Sample records for driven cargo pump

  1. 46 CFR 32.50-35 - Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Remote manual shutdown for internal combustion engine... for Cargo Handling § 32.50-35 Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels—TB/ALL. (a) Any tank vessel which is equipped with an internal combustion engine...

  2. 46 CFR 32.50-35 - Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Remote manual shutdown for internal combustion engine... for Cargo Handling § 32.50-35 Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels—TB/ALL. (a) Any tank vessel which is equipped with an internal combustion engine...

  3. 46 CFR 32.50-35 - Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Remote manual shutdown for internal combustion engine... for Cargo Handling § 32.50-35 Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels—TB/ALL. (a) Any tank vessel which is equipped with an internal combustion engine...

  4. 46 CFR 32.50-35 - Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Remote manual shutdown for internal combustion engine... for Cargo Handling § 32.50-35 Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels—TB/ALL. (a) Any tank vessel which is equipped with an internal combustion engine...

  5. 46 CFR 32.50-35 - Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Remote manual shutdown for internal combustion engine... for Cargo Handling § 32.50-35 Remote manual shutdown for internal combustion engine driven cargo pump on tank vessels—TB/ALL. (a) Any tank vessel which is equipped with an internal combustion engine...

  6. 46 CFR 95.10-5 - Fire pumps.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire pumps. 95.10-5 Section 95.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS FIRE PROTECTION EQUIPMENT Fire Main System, Details § 95.10-5 Fire pumps. (a) Vessels shall be equipped with independently driven fire...

  7. 46 CFR 154.315 - Cargo pump and cargo compressor rooms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pump and cargo compressor rooms. 154.315 Section... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Ship Arrangements § 154.315 Cargo pump and cargo compressor rooms. (a) Cargo pump rooms and cargo...

  8. 46 CFR 154.534 - Cargo pumps and cargo compressors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pumps and cargo compressors. 154.534 Section 154... SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Cargo and Process Piping Systems § 154.534 Cargo pumps and cargo compressors. Cargo pumps and...

  9. 46 CFR 111.106-13 - Cargo handling devices or cargo pump rooms handling flammable or combustible cargoes.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... pierced by fixed lights, drive shafts, and pump-engine control rods, provided that the shafts and rods are... 46 Shipping 4 2014-10-01 2014-10-01 false Cargo handling devices or cargo pump rooms handling... OSVs § 111.106-13 Cargo handling devices or cargo pump rooms handling flammable or combustible cargoes...

  10. 46 CFR 153.333 - Cargo pump discharge pressure gauge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pump discharge pressure gauge. 153.333 Section 153... SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Pumprooms § 153.333 Cargo pump discharge pressure gauge. Each cargo pump within a pump-room must...

  11. 46 CFR 153.333 - Cargo pump discharge pressure gauge.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Cargo pump discharge pressure gauge. 153.333 Section 153... SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Pumprooms § 153.333 Cargo pump discharge pressure gauge. Each cargo pump within a pump-room must...

  12. 46 CFR 153.333 - Cargo pump discharge pressure gauge.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Cargo pump discharge pressure gauge. 153.333 Section 153... SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Pumprooms § 153.333 Cargo pump discharge pressure gauge. Each cargo pump within a pump-room must...

  13. 46 CFR 153.333 - Cargo pump discharge pressure gauge.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Cargo pump discharge pressure gauge. 153.333 Section 153... SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Pumprooms § 153.333 Cargo pump discharge pressure gauge. Each cargo pump within a pump-room must...

  14. 46 CFR 153.333 - Cargo pump discharge pressure gauge.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Cargo pump discharge pressure gauge. 153.333 Section 153... SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Pumprooms § 153.333 Cargo pump discharge pressure gauge. Each cargo pump within a pump-room must...

  15. 46 CFR 36.10-1 - Cargo pump relief valves-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo pump relief valves-TB/ALL. 36.10-1 Section 36.10-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS ELEVATED TEMPERATURE CARGOES Piping, Valves, Fittings, and Accessory Equipment § 36.10-1 Cargo pump relief valves—TB/ALL. (a) Cargo pump...

  16. 46 CFR 153.285 - Valving for cargo pump manifolds.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Valving for cargo pump manifolds. 153.285 Section 153... SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.285 Valving for cargo pump manifolds. (a) When cargo...

  17. 46 CFR 153.336 - Special cargo pump or pumproom requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Special cargo pump or pumproom requirements. 153.336... CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Pumprooms § 153.336 Special cargo pump or pumproom requirements. (a) When Table 1 refers to...

  18. 46 CFR 64.89 - Cargo pump unit.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... with the product to be pumped. (d) A diesel engine that is used to drive a cargo pump must have a spark...) The cargo pump power unit must be— (1) Diesel; (2) Hydraulic; (3) Pneumatic; or (4) Electric. (c) The...

  19. 46 CFR 64.89 - Cargo pump unit.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... with the product to be pumped. (d) A diesel engine that is used to drive a cargo pump must have a spark...) The cargo pump power unit must be— (1) Diesel; (2) Hydraulic; (3) Pneumatic; or (4) Electric. (c) The...

  20. 46 CFR 64.89 - Cargo pump unit.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... with the product to be pumped. (d) A diesel engine that is used to drive a cargo pump must have a spark...) The cargo pump power unit must be— (1) Diesel; (2) Hydraulic; (3) Pneumatic; or (4) Electric. (c) The...

  1. 46 CFR 64.89 - Cargo pump unit.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... with the product to be pumped. (d) A diesel engine that is used to drive a cargo pump must have a spark...) The cargo pump power unit must be— (1) Diesel; (2) Hydraulic; (3) Pneumatic; or (4) Electric. (c) The...

  2. 46 CFR 154.476 - Cargo transfer devices and means.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of cargo transfer, such as another pump or gas pressurization. (b) If cargo is transferred by gas... SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Support System § 154.476 Cargo transfer devices and means. (a) If a cargo pump in a cargo tank is...

  3. 46 CFR 154.1010 - Electrical equipment in gas-dangerous space or zone.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... (c) A submerged cargo pump motor may be in a cargo tank if: (1) Low liquid level, motor current, or pump discharge pressure automatically shuts down power to the pump motor if the pump loses suction; (2) There is an audible and visual alarm at the cargo control station that actuates if the motor shuts down...

  4. 46 CFR 154.1010 - Electrical equipment in gas-dangerous space or zone.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... (c) A submerged cargo pump motor may be in a cargo tank if: (1) Low liquid level, motor current, or pump discharge pressure automatically shuts down power to the pump motor if the pump loses suction; (2) There is an audible and visual alarm at the cargo control station that actuates if the motor shuts down...

  5. 46 CFR 32.50-5 - Cargo pump gauges on tank vessels constructed on or after November 10, 1936-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... point visible with respect to the pump controls. [CGFR 65-50, 30 FR 16671, Dec. 30, 1965, as amended by... 46 Shipping 1 2014-10-01 2014-10-01 false Cargo pump gauges on tank vessels constructed on or... SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo...

  6. 46 CFR 32.50-5 - Cargo pump gauges on tank vessels constructed on or after November 10, 1936-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... point visible with respect to the pump controls. [CGFR 65-50, 30 FR 16671, Dec. 30, 1965, as amended by... 46 Shipping 1 2012-10-01 2012-10-01 false Cargo pump gauges on tank vessels constructed on or... SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo...

  7. 46 CFR 32.50-5 - Cargo pump gauges on tank vessels constructed on or after November 10, 1936-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... point visible with respect to the pump controls. [CGFR 65-50, 30 FR 16671, Dec. 30, 1965, as amended by... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo pump gauges on tank vessels constructed on or... SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo...

  8. 46 CFR 32.50-5 - Cargo pump gauges on tank vessels constructed on or after November 10, 1936-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... point visible with respect to the pump controls. [CGFR 65-50, 30 FR 16671, Dec. 30, 1965, as amended by... 46 Shipping 1 2013-10-01 2013-10-01 false Cargo pump gauges on tank vessels constructed on or... SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo...

  9. 46 CFR 32.50-5 - Cargo pump gauges on tank vessels constructed on or after November 10, 1936-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... point visible with respect to the pump controls. [CGFR 65-50, 30 FR 16671, Dec. 30, 1965, as amended by... 46 Shipping 1 2011-10-01 2011-10-01 false Cargo pump gauges on tank vessels constructed on or... SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo...

  10. 46 CFR 56.50-50 - Bilge and ballast piping.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... defined in 49 CFR part 173, in enclosed cargo spaces, the bilge-pumping system must be designed to ensure against inadvertent pumping of such liquids through machinery-space piping or pumps. (5) For each vessel... enclosed cargo spaces on either the bulkhead deck of a passenger vessel or the freeboard deck of a cargo...

  11. 46 CFR 56.50-50 - Bilge and ballast piping.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... defined in 49 CFR part 173, in enclosed cargo spaces, the bilge-pumping system must be designed to ensure against inadvertent pumping of such liquids through machinery-space piping or pumps. (5) For each vessel... enclosed cargo spaces on either the bulkhead deck of a passenger vessel or the freeboard deck of a cargo...

  12. 46 CFR 56.50-50 - Bilge and ballast piping.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... defined in 49 CFR part 173, in enclosed cargo spaces, the bilge-pumping system must be designed to ensure against inadvertent pumping of such liquids through machinery-space piping or pumps. (5) For each vessel... enclosed cargo spaces on either the bulkhead deck of a passenger vessel or the freeboard deck of a cargo...

  13. 46 CFR 56.50-50 - Bilge and ballast piping.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... defined in 49 CFR part 173, in enclosed cargo spaces, the bilge-pumping system must be designed to ensure against inadvertent pumping of such liquids through machinery-space piping or pumps. (5) For each vessel... enclosed cargo spaces on either the bulkhead deck of a passenger vessel or the freeboard deck of a cargo...

  14. 46 CFR 154.519 - Piping relief valves.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Cargo and... cargo that is specially approved by the Commandant (CG-522). (b) A relief valve on a cargo pump that protects the cargo piping system must discharge into the pump suction. [CGD 74-289, 44 FR 26009, May 3...

  15. 46 CFR 105.25-7 - Ventilation systems for cargo tank or pumping system compartment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Ventilation systems for cargo tank or pumping system compartment. 105.25-7 Section 105.25-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Additional Requirements-When Cargo Tanks Are Installed...

  16. 46 CFR 32.50-3 - Cargo discharge-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Cargo discharge-TB/ALL. 32.50-3 Section 32.50-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-3 Cargo discharge—TB/ALL. (a) Pumps or other...

  17. 46 CFR 32.50-3 - Cargo discharge-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Cargo discharge-TB/ALL. 32.50-3 Section 32.50-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-3 Cargo discharge—TB/ALL. (a) Pumps or other...

  18. 46 CFR 32.50-3 - Cargo discharge-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo discharge-TB/ALL. 32.50-3 Section 32.50-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-3 Cargo discharge—TB/ALL. (a) Pumps or other...

  19. 46 CFR 32.50-3 - Cargo discharge-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Cargo discharge-TB/ALL. 32.50-3 Section 32.50-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-3 Cargo discharge—TB/ALL. (a) Pumps or other...

  20. 46 CFR 32.50-3 - Cargo discharge-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Cargo discharge-TB/ALL. 32.50-3 Section 32.50-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-3 Cargo discharge—TB/ALL. (a) Pumps or other...

  1. 46 CFR 153.334 - Bilge pumping systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... pumping system must have: (1) Complete remote operating controls outside the cargo pumproom; and (2) An... 46 Shipping 5 2010-10-01 2010-10-01 false Bilge pumping systems. 153.334 Section 153.334 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING...

  2. 46 CFR 153.330 - Access.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Cargo Pumprooms § 153.330 Access. (a) The access door to a cargo pump-room must open on the weatheredeck. (b) The access way to a cargo pump-room and its valving must allow passage of a man wearing the breathing apparatus required by § 153...

  3. 46 CFR 154.1200 - Mechanical ventilation system: General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Each cargo compressor room, pump room, gas-dangerous cargo control station, and space that contains... motors for cargo handling equipment. (2) Each gas-safe cargo control station in the cargo area. (3) Each...

  4. 46 CFR 154.1200 - Mechanical ventilation system: General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Each cargo compressor room, pump room, gas-dangerous cargo control station, and space that contains... motors for cargo handling equipment. (2) Each gas-safe cargo control station in the cargo area. (3) Each...

  5. 46 CFR 154.1200 - Mechanical ventilation system: General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Each cargo compressor room, pump room, gas-dangerous cargo control station, and space that contains... motors for cargo handling equipment. (2) Each gas-safe cargo control station in the cargo area. (3) Each...

  6. 46 CFR 64.89 - Cargo pump unit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... discharges a portable tank must be— (1) Constructed of materials that are compatible with the product to be...) The cargo pump power unit must be— (1) Diesel; (2) Hydraulic; (3) Pneumatic; or (4) Electric. (c) The...

  7. 33 CFR 155.780 - Emergency shutdown.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the vessel to stop the flow of oil or hazardous material. (b) The means to stop the flow may be a pump control, a quick-acting, power actuated valve, or an operating procedure. If an emergency pump control is... through the stopped pump. (c) The means to stop the flow must be operable from the cargo deck, cargo...

  8. 33 CFR 155.780 - Emergency shutdown.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the vessel to stop the flow of oil or hazardous material. (b) The means to stop the flow may be a pump control, a quick-acting, power actuated valve, or an operating procedure. If an emergency pump control is... through the stopped pump. (c) The means to stop the flow must be operable from the cargo deck, cargo...

  9. 33 CFR 155.780 - Emergency shutdown.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the vessel to stop the flow of oil or hazardous material. (b) The means to stop the flow may be a pump control, a quick-acting, power actuated valve, or an operating procedure. If an emergency pump control is... through the stopped pump. (c) The means to stop the flow must be operable from the cargo deck, cargo...

  10. 33 CFR 155.780 - Emergency shutdown.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the vessel to stop the flow of oil or hazardous material. (b) The means to stop the flow may be a pump control, a quick-acting, power actuated valve, or an operating procedure. If an emergency pump control is... through the stopped pump. (c) The means to stop the flow must be operable from the cargo deck, cargo...

  11. 33 CFR 155.780 - Emergency shutdown.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the vessel to stop the flow of oil or hazardous material. (b) The means to stop the flow may be a pump control, a quick-acting, power actuated valve, or an operating procedure. If an emergency pump control is... through the stopped pump. (c) The means to stop the flow must be operable from the cargo deck, cargo...

  12. 46 CFR 154.554 - Cargo hose: Bursting pressure.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Cargo... cargo tank, the cargo pump discharge, or the vapor compressor discharge must have a bursting pressure of...

  13. 46 CFR 151.50-41 - Carbon disulfide (carbon bisulfide).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... emergency sounding. (d) If a cargo discharge pump is used, it shall be inserted through a cylindrical well... before attempting pump removal. (e) Water or inert gas displacement may be used for discharging cargo... discharging may be used with pressure type tanks only. (f) Adequate natural ventilation shall be provided for...

  14. 46 CFR 32.50-30 - Cargo hose-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Cargo hose-TB/ALL. 32.50-30 Section 32.50-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-30 Cargo hose—TB/ALL. Cargo hose carried on...

  15. 46 CFR 32.50-30 - Cargo hose-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Cargo hose-TB/ALL. 32.50-30 Section 32.50-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-30 Cargo hose—TB/ALL. Cargo hose carried on...

  16. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  17. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  18. 46 CFR 32.50-30 - Cargo hose-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo hose-TB/ALL. 32.50-30 Section 32.50-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-30 Cargo hose—TB/ALL. Cargo hose carried on...

  19. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  20. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  1. 46 CFR 32.50-30 - Cargo hose-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Cargo hose-TB/ALL. 32.50-30 Section 32.50-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-30 Cargo hose—TB/ALL. Cargo hose carried on...

  2. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  3. 46 CFR 32.50-30 - Cargo hose-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Cargo hose-TB/ALL. 32.50-30 Section 32.50-30 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS SPECIAL EQUIPMENT, MACHINERY, AND HULL REQUIREMENTS Pumps, Piping, and Hose for Cargo Handling § 32.50-30 Cargo hose—TB/ALL. Cargo hose carried on...

  4. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  5. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  6. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  7. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  8. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  9. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  10. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  11. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  12. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  13. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  14. 46 CFR 154.310 - Cargo piping systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Arrangements § 154.310 Cargo piping systems. Cargo liquid or vapor piping must: (a) Be separated from other...); (b) Not enter or pass through any accommodation, service, or control space; (c) Except as allowed under § 154.703, not enter or pass through a machinery space other than a cargo pump or compressor room...

  15. 46 CFR 154.310 - Cargo piping systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Arrangements § 154.310 Cargo piping systems. Cargo liquid or vapor piping must: (a) Be separated from other...); (b) Not enter or pass through any accommodation, service, or control space; (c) Except as allowed under § 154.703, not enter or pass through a machinery space other than a cargo pump or compressor room...

  16. 46 CFR 154.310 - Cargo piping systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Arrangements § 154.310 Cargo piping systems. Cargo liquid or vapor piping must: (a) Be separated from other...); (b) Not enter or pass through any accommodation, service, or control space; (c) Except as allowed under § 154.703, not enter or pass through a machinery space other than a cargo pump or compressor room...

  17. 46 CFR 154.310 - Cargo piping systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Arrangements § 154.310 Cargo piping systems. Cargo liquid or vapor piping must: (a) Be separated from other...); (b) Not enter or pass through any accommodation, service, or control space; (c) Except as allowed under § 154.703, not enter or pass through a machinery space other than a cargo pump or compressor room...

  18. 46 CFR 154.310 - Cargo piping systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Arrangements § 154.310 Cargo piping systems. Cargo liquid or vapor piping must: (a) Be separated from other...); (b) Not enter or pass through any accommodation, service, or control space; (c) Except as allowed under § 154.703, not enter or pass through a machinery space other than a cargo pump or compressor room...

  19. 46 CFR 153.1010 - Alkylene oxides.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures... another containment system; (3) Alkylene oxide is discharged only by an intank cargo pump or inert gas...

  20. 46 CFR 153.1010 - Alkylene oxides.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures... another containment system; (3) Alkylene oxide is discharged only by an intank cargo pump or inert gas...

  1. 46 CFR 153.1010 - Alkylene oxides.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures... another containment system; (3) Alkylene oxide is discharged only by an intank cargo pump or inert gas...

  2. 46 CFR 153.1010 - Alkylene oxides.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures... another containment system; (3) Alkylene oxide is discharged only by an intank cargo pump or inert gas...

  3. 33 CFR 157.126 - Pumps.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Washing (COW) System on Tank Vessels Design, Equipment, and Installation § 157.126 Pumps. (a) Crude oil must be supplied to the COW machines by COW system pumps or cargo pumps. (b) The pumps under paragraph...) A sufficient pressure and flow is supplied to allow the simultaneous operation of those COW machines...

  4. 46 CFR 154.1200 - Mechanical ventilation system: General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... gas-safe space in the cargo area. (4) Each space that contains inert gas generators, except main...) Each cargo compressor room, pump room, gas-dangerous cargo control station, and space that contains... following must have a supply-type mechanical ventilation system: (1) Each space that contains electric...

  5. 46 CFR 64.93 - Pump controls.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Pump controls. 64.93 Section 64.93 Shipping COAST GUARD... SYSTEMS Cargo Handling System § 64.93 Pump controls. (a) A pressure gauge must be installed— (1) On the pump discharge; (2) Near the pump controls; and (3) Visible to the operator. (b) A pump must have a...

  6. 46 CFR 64.93 - Pump controls.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Pump controls. 64.93 Section 64.93 Shipping COAST GUARD... SYSTEMS Cargo Handling System § 64.93 Pump controls. (a) A pressure gauge must be installed— (1) On the pump discharge; (2) Near the pump controls; and (3) Visible to the operator. (b) A pump must have a...

  7. 46 CFR 64.93 - Pump controls.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Pump controls. 64.93 Section 64.93 Shipping COAST GUARD... SYSTEMS Cargo Handling System § 64.93 Pump controls. (a) A pressure gauge must be installed— (1) On the pump discharge; (2) Near the pump controls; and (3) Visible to the operator. (b) A pump must have a...

  8. 46 CFR 64.93 - Pump controls.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Pump controls. 64.93 Section 64.93 Shipping COAST GUARD... SYSTEMS Cargo Handling System § 64.93 Pump controls. (a) A pressure gauge must be installed— (1) On the pump discharge; (2) Near the pump controls; and (3) Visible to the operator. (b) A pump must have a...

  9. 46 CFR 64.93 - Pump controls.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Pump controls. 64.93 Section 64.93 Shipping COAST GUARD... SYSTEMS Cargo Handling System § 64.93 Pump controls. (a) A pressure gauge must be installed— (1) On the pump discharge; (2) Near the pump controls; and (3) Visible to the operator. (b) A pump must have a...

  10. 46 CFR 64.95 - Piping.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... operator at the cargo pump controls. (c) Each pipe and valve in the pumping system that has an open end... with the procedures in § 50.25-10 of this chapter. (e) A non-return valve must be in the pump discharge...

  11. 46 CFR 64.95 - Piping.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... operator at the cargo pump controls. (c) Each pipe and valve in the pumping system that has an open end... with the procedures in § 50.25-10 of this chapter. (e) A non-return valve must be in the pump discharge...

  12. 46 CFR 64.95 - Piping.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... operator at the cargo pump controls. (c) Each pipe and valve in the pumping system that has an open end... with the procedures in § 50.25-10 of this chapter. (e) A non-return valve must be in the pump discharge...

  13. 46 CFR 64.95 - Piping.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... operator at the cargo pump controls. (c) Each pipe and valve in the pumping system that has an open end... with the procedures in § 50.25-10 of this chapter. (e) A non-return valve must be in the pump discharge...

  14. 46 CFR 64.95 - Piping.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... operator at the cargo pump controls. (c) Each pipe and valve in the pumping system that has an open end... with the procedures in § 50.25-10 of this chapter. (e) A non-return valve must be in the pump discharge...

  15. Container System Hardware

    DTIC Science & Technology

    1989-01-01

    7 class high - speed containerships and their subsequent conversion to a cargo configuration specifically designed for rapid load/unload of military...storage and pump modules though it could be used for general cargo and organizational property. STATUS A procurement contract for 402 shipping frames was...with a secondary role of containerized cargo transfer. The craft will be capable of carrying over 100 short tons of cargo , at a speed of 8 to 15 knots

  16. Container System Hardware Status Report 1990

    DTIC Science & Technology

    1990-01-01

    class high - speed containerships and their subsequent conversion to a cargo configuration specifically designed for rapid load/unload of military...pump modules though it could be used for general cargo and organizational property. STATUS A procurement contract for 402 shipping frames was conducted...for various cargo heights. The second type of flatrack has a maximum cargo capacity of 72 short-tons and has comer posts 13 feet high . The comer posts

  17. 46 CFR 153.520 - Special requirements for carbon disulfide.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and... carrying carbon disulfide must meet the following: (a) Each cargo pump must be of the intank type and...

  18. 46 CFR 129.540 - Remote stopping-systems on OSVs of 100 or more gross tons.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., outside the space ventilated. (4) For each fuel-oil pump, outside the space containing the pump. (5) For each cargo-transfer pump for combustible and flammable liquid, at each transfer-control station. (c...

  19. 46 CFR 129.540 - Remote stopping-systems on OSVs of 100 or more gross tons.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... pump for bilge slop or dirty oil, at the deck discharge. (3) For each powered ventilation system, outside the space ventilated. (4) For each fuel-oil pump, outside the space containing the pump. (5) For each cargo-transfer pump for combustible and flammable liquid, at each transfer-control station. (c...

  20. Transportable Pumps Could Save Oil Cargoes

    NASA Technical Reports Server (NTRS)

    Burns, R.

    1984-01-01

    Transportable pumps designed for firefighting used to salvage crude oil from tankships leaking, burning, or grounded. Pump incorporated into self-contained transportable module along with engine and controls. Module carried by helicopter, boat, or van to site of fire provides large quantities of water at high pressure in firefighting mode or pump oil into barge in salvage mode.

  1. 46 CFR 129.540 - Remote stopping-systems on OSVs of 100 or more gross tons.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... pump for bilge slop or dirty oil, at the deck discharge. (3) For each powered ventilation system, outside the space ventilated. (4) For each fuel-oil pump, outside the space containing the pump. (5) For each cargo-transfer pump for combustible and flammable liquid, at each transfer-control station. (c...

  2. 46 CFR 129.540 - Remote stopping-systems on OSVs of 100 or more gross tons.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... pump for bilge slop or dirty oil, at the deck discharge. (3) For each powered ventilation system, outside the space ventilated. (4) For each fuel-oil pump, outside the space containing the pump. (5) For each cargo-transfer pump for combustible and flammable liquid, at each transfer-control station. (c...

  3. 46 CFR 32.65-20 - Pumprooms-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... bulkhead between the pumproom and the pump-engine compartment may be pierced by fixed lights, drive shaft and pump-engine control rods, provided that the shafts and rods are fitted with stuffing boxes where... their cargo pumps isolated from all sources of vapor ignition by gastight bulkheads. Totally enclosed...

  4. 46 CFR 32.65-20 - Pumprooms-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... bulkhead between the pumproom and the pump-engine compartment may be pierced by fixed lights, drive shaft and pump-engine control rods, provided that the shafts and rods are fitted with stuffing boxes where... their cargo pumps isolated from all sources of vapor ignition by gastight bulkheads. Totally enclosed...

  5. 46 CFR 32.65-20 - Pumprooms-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... bulkhead between the pumproom and the pump-engine compartment may be pierced by fixed lights, drive shaft and pump-engine control rods, provided that the shafts and rods are fitted with stuffing boxes where... their cargo pumps isolated from all sources of vapor ignition by gastight bulkheads. Totally enclosed...

  6. 46 CFR 32.65-20 - Pumprooms-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... bulkhead between the pumproom and the pump-engine compartment may be pierced by fixed lights, drive shaft and pump-engine control rods, provided that the shafts and rods are fitted with stuffing boxes where... their cargo pumps isolated from all sources of vapor ignition by gastight bulkheads. Totally enclosed...

  7. 46 CFR 32.65-20 - Pumprooms-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... bulkhead between the pumproom and the pump-engine compartment may be pierced by fixed lights, drive shaft and pump-engine control rods, provided that the shafts and rods are fitted with stuffing boxes where... their cargo pumps isolated from all sources of vapor ignition by gastight bulkheads. Totally enclosed...

  8. 46 CFR 38.10-10 - Cargo piping-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS LIQUEFIED FLAMMABLE GASES Piping, Valves... pumps or vapor compressors, the design pressure shall not be less than the pump or compressor discharge... shall not be less than the total discharge head of the pump or compressor. (b) Piping subject to tank...

  9. 46 CFR 56.50-55 - Bilge pumps.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Type of vessel Waters navigated Power pumps (1) Hand pumps Sailing Ocean and coastwise Two (2) Manned... Vessels Vessel length, in feet Passenger vessels 1 International voyages 3 Ocean, coast-wise and Great Lakes All other waters Dry-cargo vessels 2 Ocean, coast-wise and Great Lakes All waters Tankvessels All...

  10. 46 CFR 56.50-55 - Bilge pumps.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Type of vessel Waters navigated Power pumps (1) Hand pumps Sailing Ocean and coastwise Two (2) Manned... Vessels Vessel length, in feet Passenger vessels 1 International voyages 3 Ocean, coast-wise and Great Lakes All other waters Dry-cargo vessels 2 Ocean, coast-wise and Great Lakes All waters Tank vessels All...

  11. 46 CFR 56.50-55 - Bilge pumps.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Type of vessel Waters navigated Power pumps (1) Hand pumps Sailing Ocean and coastwise Two (2) Manned... Vessels Vessel length, in feet Passenger vessels 1 International voyages 3 Ocean, coast-wise and Great Lakes All other waters Dry-cargo vessels 2 Ocean, coast-wise and Great Lakes All waters Tankvessels All...

  12. 46 CFR 56.50-55 - Bilge pumps.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Type of vessel Waters navigated Power pumps (1) Hand pumps Sailing Ocean and coastwise Two (2) Manned... Vessels Vessel length, in feet Passenger vessels 1 International voyages 3 Ocean, coast-wise and Great Lakes All other waters Dry-cargo vessels 2 Ocean, coast-wise and Great Lakes All waters Tankvessels All...

  13. 29 CFR Appendix B to Subpart B of... - Reprint of U.S. Coast Guard Regulations Referenced in Subpart B, for Determination of Coast Guard...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils...

  14. 29 CFR Appendix B to Subpart B of... - Reprint of U.S. Coast Guard Regulations Referenced in Subpart B, for Determination of Coast Guard...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils...

  15. 29 CFR Appendix B to Subpart B of... - Reprint of U.S. Coast Guard Regulations Referenced in Subpart B, for Determination of Coast Guard...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils...

  16. 29 CFR Appendix B to Subpart B of... - Reprint of U.S. Coast Guard Regulations Referenced in Subpart B, for Determination of Coast Guard...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils...

  17. 29 CFR Appendix B to Subpart B of... - Reprint of U.S. Coast Guard Regulations Referenced in Subpart B, for Determination of Coast Guard...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections... cargo tanks; or (2) Within or on the boundaries of fuel tanks; or (3) To pipe lines, heating coils...

  18. 46 CFR 153.336 - Special cargo pump or pumproom requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 153.336 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and... low pressure breathing quality air supply system for use with the breathing apparatus in the pumproom...

  19. 46 CFR 153.336 - Special cargo pump or pumproom requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 153.336 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and... low pressure breathing quality air supply system for use with the breathing apparatus in the pumproom...

  20. 46 CFR 153.336 - Special cargo pump or pumproom requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Section 153.336 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and... low pressure breathing quality air supply system for use with the breathing apparatus in the pumproom...

  1. 46 CFR 153.336 - Special cargo pump or pumproom requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 153.336 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and... low pressure breathing quality air supply system for use with the breathing apparatus in the pumproom...

  2. 46 CFR 61.20-3 - Main and auxiliary machinery and associated equipment, including fluid control systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... control for the means of stopping machinery driving forced and induced draft fans, fuel oil transfer pumps, fuel oil unit pumps, and fans in the ventilation systems serving machinery and cargo spaces shall be...

  3. 46 CFR 56.50-55 - Bilge pumps.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Each self-propelled vessel must be provided with a power-driven pump or pumps connected to the bilge... power-driven pump is required. (See Part 171 of this chapter for determination of criterion numeral.) 5... available, or where a suitable water supply is available from a power-driven pump of adequate pressure and...

  4. Local synaptic signaling enhances the stochastic transport of motor-driven cargo in neurons

    NASA Astrophysics Data System (ADS)

    Newby, Jay; Bressloff, Paul C.

    2010-09-01

    The tug-of-war model of motor-driven cargo transport is formulated as an intermittent trapping process. An immobile trap, representing the cellular machinery that sequesters a motor-driven cargo for eventual use, is located somewhere within a microtubule track. A particle representing a motor-driven cargo that moves randomly with a forward bias is introduced at the beginning of the track. The particle switches randomly between a fast moving phase and a slow moving phase. When in the slow moving phase, the particle can be captured by the trap. To account for the possibility that the particle avoids the trap, an absorbing boundary is placed at the end of the track. Two local signaling mechanisms—intended to improve the chances of capturing the target—are considered by allowing the trap to affect the tug-of-war parameters within a small region around itself. The first is based on a localized adenosine triphosphate (ATP) concentration gradient surrounding a synapse, and the second is based on a concentration of tau—a microtubule-associated protein involved in Alzheimer's disease—coating the microtubule near the synapse. It is shown that both mechanisms can lead to dramatic improvements in the capture probability, with a minimal increase in the mean capture time. The analysis also shows that tau can cause a cargo to undergo random oscillations, which could explain some experimental observations.

  5. 46 CFR 127.225 - Structural fire protection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... wheelhouses, containing accommodation, service and control spaces, facing the cargo area must be constructed of steel and comply with §§ 32.56-20, 32.56-21, and 32.56-22 of this chapter. (d) Cargo pump rooms must be separated from accommodation spaces, service spaces, and control stations by A-60 divisions. (e...

  6. 46 CFR 153.565 - Special requirement for temperature sensors.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Special requirement for temperature sensors. 153.565... Equipment Special Requirements § 153.565 Special requirement for temperature sensors. If a cargo listed in table 1 of this part refers to this section, temperature sensors must be used to monitor the cargo pump...

  7. 46 CFR 153.565 - Special requirement for temperature sensors.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Special requirement for temperature sensors. 153.565... Equipment Special Requirements § 153.565 Special requirement for temperature sensors. If a cargo listed in table 1 of this part refers to this section, temperature sensors must be used to monitor the cargo pump...

  8. 46 CFR 153.565 - Special requirement for temperature sensors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Special requirement for temperature sensors. 153.565... Equipment Special Requirements § 153.565 Special requirement for temperature sensors. If a cargo listed in table 1 of this part refers to this section, temperature sensors must be used to monitor the cargo pump...

  9. 49 CFR 178.345-9 - Pumps, piping, hoses and connections.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... there will be no leakage when connected. (d) Suitable provision must be made to allow for and prevent... any load applied by loading/unloading or charging lines connected to the cargo tank cannot cause damage resulting in loss of lading from the cargo tank. (h) Use of a nonmetallic pipe, valve or...

  10. 46 CFR 154.350 - Bilge and ballast systems in the cargo area.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., and insulation spaces must have a means of sounding the space or other means of detecting liquid leakage specially approved by the Commandant (CG-522). (b) Each hold and insulation space must have a bilge drainage system. (c) Interbarrier spaces must have an eductor or pump for removing liquid cargo...

  11. 46 CFR 154.350 - Bilge and ballast systems in the cargo area.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., and insulation spaces must have a means of sounding the space or other means of detecting liquid leakage specially approved by the Commandant (CG-522). (b) Each hold and insulation space must have a bilge drainage system. (c) Interbarrier spaces must have an eductor or pump for removing liquid cargo...

  12. 46 CFR 154.350 - Bilge and ballast systems in the cargo area.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., and insulation spaces must have a means of sounding the space or other means of detecting liquid leakage specially approved by the Commandant (CG-ENG). (b) Each hold and insulation space must have a bilge drainage system. (c) Interbarrier spaces must have an eductor or pump for removing liquid cargo...

  13. 46 CFR 154.350 - Bilge and ballast systems in the cargo area.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., and insulation spaces must have a means of sounding the space or other means of detecting liquid leakage specially approved by the Commandant (CG-ENG). (b) Each hold and insulation space must have a bilge drainage system. (c) Interbarrier spaces must have an eductor or pump for removing liquid cargo...

  14. 46 CFR 154.350 - Bilge and ballast systems in the cargo area.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., and insulation spaces must have a means of sounding the space or other means of detecting liquid leakage specially approved by the Commandant (CG-ENG). (b) Each hold and insulation space must have a bilge drainage system. (c) Interbarrier spaces must have an eductor or pump for removing liquid cargo...

  15. Transportation of Nanoscale Cargoes by Myosin Propelled Actin Filaments

    PubMed Central

    Persson, Malin; Gullberg, Maria; Tolf, Conny; Lindberg, A. Michael; Månsson, Alf; Kocer, Armagan

    2013-01-01

    Myosin II propelled actin filaments move ten times faster than kinesin driven microtubules and are thus attractive candidates as cargo-transporting shuttles in motor driven lab-on-a-chip devices. In addition, actomyosin-based transportation of nanoparticles is useful in various fundamental studies. However, it is poorly understood how actomyosin function is affected by different number of nanoscale cargoes, by cargo size, and by the mode of cargo-attachment to the actin filament. This is studied here using biotin/fluorophores, streptavidin, streptavidin-coated quantum dots, and liposomes as model cargoes attached to monomers along the actin filaments (“side-attached”) or to the trailing filament end via the plus end capping protein CapZ. Long-distance transportation (>100 µm) could be seen for all cargoes independently of attachment mode but the fraction of motile filaments decreased with increasing number of side-attached cargoes, a reduction that occurred within a range of 10–50 streptavidin molecules, 1–10 quantum dots or with just 1 liposome. However, as observed by monitoring these motile filaments with the attached cargo, the velocity was little affected. This also applied for end-attached cargoes where the attachment was mediated by CapZ. The results with side-attached cargoes argue against certain models for chemomechanical energy transduction in actomyosin and give important insights of relevance for effective exploitation of actomyosin-based cargo-transportation in molecular diagnostics and other nanotechnological applications. The attachment of quantum dots via CapZ, without appreciable modulation of actomyosin function, is useful in fundamental studies as exemplified here by tracking with nanometer accuracy. PMID:23437074

  16. Low-thrust chemical propulsion system pump technology

    NASA Technical Reports Server (NTRS)

    Sabiers, R. L.; Siebenhaar, A.

    1981-01-01

    Candidate pump and driver systems for low thrust cargo orbit transfer vehicle engines which deliver large space structures to geosynchronous equatorial orbit and beyond are evaluated. The pumps operate to 68 atmospheres (1000 psi) discharge pressure and flowrates suited to cryogenic engines using either LOX/methane or LOX/hydrogen propellants in thrust ranges from 445 to 8900 N (100 to 2000 lb F). Analysis of the various pumps and drivers indicate that the low specific speed requirement will make high fluid efficiencies difficult to achieve. As such, multiple stages are required. In addition, all pumps require inducer stages. The most attractive main pumps are the multistage centrifugal pumps.

  17. 46 CFR 132.120 - Fire pumps.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... with one self-priming power-driven fire pump capable of delivering a single stream of water from the..., the pump required by paragraph (a) of this section may be driven by one of the engines. If only one propulsion engine is installed, the pump must be driven by a source of power independent of the engine. (e...

  18. 46 CFR 132.120 - Fire pumps.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... vessel must be equipped with one self-priming power-driven fire pump capable of delivering a single... propulsion engines are installed, the pump required by paragraph (a) of this section may be driven by one of the engines. If only one propulsion engine is installed, the pump must be driven by a source of power...

  19. 46 CFR 132.120 - Fire pumps.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... vessel must be equipped with one self-priming power-driven fire pump capable of delivering a single... propulsion engines are installed, the pump required by paragraph (a) of this section may be driven by one of the engines. If only one propulsion engine is installed, the pump must be driven by a source of power...

  20. 46 CFR 132.120 - Fire pumps.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... vessel must be equipped with one self-priming power-driven fire pump capable of delivering a single... propulsion engines are installed, the pump required by paragraph (a) of this section may be driven by one of the engines. If only one propulsion engine is installed, the pump must be driven by a source of power...

  1. 49 CFR 178.345-9 - Pumps, piping, hoses and connections.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... greater of 120 psig or 4.8 times the MAWP of the cargo tank, and must be designed so that there will be no... sufficient strength, or be protected by a sacrificial device, such that any load applied by loading/unloading or charging lines connected to the cargo tank cannot cause damage resulting in loss of lading from...

  2. 49 CFR 178.345-9 - Pumps, piping, hoses and connections.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... greater of 120 psig or 4.8 times the MAWP of the cargo tank, and must be designed so that there will be no... sufficient strength, or be protected by a sacrificial device, such that any load applied by loading/unloading or charging lines connected to the cargo tank cannot cause damage resulting in loss of lading from...

  3. 49 CFR 178.345-9 - Pumps, piping, hoses and connections.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... greater of 120 psig or 4.8 times the MAWP of the cargo tank, and must be designed so that there will be no... sufficient strength, or be protected by a sacrificial device, such that any load applied by loading/unloading or charging lines connected to the cargo tank cannot cause damage resulting in loss of lading from...

  4. 49 CFR 178.345-9 - Pumps, piping, hoses and connections.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... greater of 120 psig or 4.8 times the MAWP of the cargo tank, and must be designed so that there will be no... sufficient strength, or be protected by a sacrificial device, such that any load applied by loading/unloading or charging lines connected to the cargo tank cannot cause damage resulting in loss of lading from...

  5. 46 CFR 35.35-45 - Auxiliary steam, air, or electric current-B/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Auxiliary steam, air, or electric current-B/ALL. 35.35... Cargo Handling § 35.35-45 Auxiliary steam, air, or electric current—B/ALL. When discharging cargo from one or more barges, the towing vessel may furnish steam, air, or electric current for pumps on barges...

  6. 46 CFR 35.35-45 - Auxiliary steam, air, or electric current-B/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Auxiliary steam, air, or electric current-B/ALL. 35.35... Cargo Handling § 35.35-45 Auxiliary steam, air, or electric current—B/ALL. When discharging cargo from one or more barges, the towing vessel may furnish steam, air, or electric current for pumps on barges...

  7. 46 CFR 35.35-45 - Auxiliary steam, air, or electric current-B/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Auxiliary steam, air, or electric current-B/ALL. 35.35... Cargo Handling § 35.35-45 Auxiliary steam, air, or electric current—B/ALL. When discharging cargo from one or more barges, the towing vessel may furnish steam, air, or electric current for pumps on barges...

  8. 46 CFR 35.35-45 - Auxiliary steam, air, or electric current-B/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Auxiliary steam, air, or electric current-B/ALL. 35.35... Cargo Handling § 35.35-45 Auxiliary steam, air, or electric current—B/ALL. When discharging cargo from one or more barges, the towing vessel may furnish steam, air, or electric current for pumps on barges...

  9. 46 CFR 35.35-45 - Auxiliary steam, air, or electric current-B/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Auxiliary steam, air, or electric current-B/ALL. 35.35... Cargo Handling § 35.35-45 Auxiliary steam, air, or electric current—B/ALL. When discharging cargo from one or more barges, the towing vessel may furnish steam, air, or electric current for pumps on barges...

  10. Microencapsulation and characterization of liposomal vesicles using a supercritical fluid process coupled with vacuum-driven cargo loading.

    PubMed

    Tsai, Wen-Chyan; Rizvi, Syed S H

    2017-06-01

    A new technique of liposomal microencapsulation, consisting of supercritical fluid extraction followed by rapid expansion of the supercritical solution and vacuum-driven cargo loading, was successfully developed. It is a continuous flow-through process without usage of any toxic organic solvent. For use as a coating material, the solubility of soy phospholipids in supercritical carbon dioxide was first determined using a dynamic equilibrium system and the data was correlated with the Chrastil model with good agreement. Liposomes were made with D-(+)-glucose as a cargo and their properties were characterized as functions of expansion pressure, temperature, and cargo loading rates. The highest encapsulation efficiency attained was 31.7% at the middle expansion pressure of 12.41MPa, highest expansion temperature of 90°C, and lowest cargo loading rate of 0.25mL/s. The large unilamellar vesicles and multivesicular vesicles were observed to be a majority of the liposomes produced using this eco-friendly process. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Hydrogel Walkers with Electro-Driven Motility for Cargo Transport.

    PubMed

    Yang, Chao; Wang, Wei; Yao, Chen; Xie, Rui; Ju, Xiao-Jie; Liu, Zhuang; Chu, Liang-Yin

    2015-08-28

    In this study, soft hydrogel walkers with electro-driven motility for cargo transport have been developed via a facile mould-assisted strategy. The hydrogel walkers consisting of polyanionic poly(2-acrylamido-2-methylpropanesulfonic acid-co-acrylamide) exhibit an arc looper-like shape with two "legs" for walking. The hydrogel walkers can reversibly bend and stretch via repeated "on/off" electro-triggers in electrolyte solution. Based on such bending/stretching behaviors, the hydrogel walkers can move their two "legs" to achieve one-directional walking motion on a rough surface via repeated "on/off" electro-triggering cycles. Moreover, the hydrogel walkers loaded with very heavy cargo also exhibit excellent walking motion for cargo transport. Such hydrogel systems create new opportunities for developing electro-controlled soft systems with simple design/fabrication strategies in the soft robotic field for remote manipulation and transportation.

  12. Natural Gas Engine-Driven Heat Pump Demonstration at DoD Installations: Performance and Reliability Summary

    DTIC Science & Technology

    2009-06-09

    ER D C/ CE R L TR -0 9 -1 0 Natural Gas Engine-Driven Heat Pump Demonstration at DoD Installations Performance and Reliability Summary...L ab or at or y Approved for public release; distribution is unlimited. ERDC/CERL TR-09-10 June 2009 Natural Gas Engine-Driven Heat Pump ...CERL TR-09-10 ii Abstract: Results of field testing natural gas engine-driven heat pumps (GHP) at six southwestern U.S. Department of Defense (DoD

  13. Performance of a vane driven-gear pump

    NASA Technical Reports Server (NTRS)

    Heald, R H

    1921-01-01

    Given here are the results of a test conducted in a wind tunnel on the performance of a vane-driven gear pump used to pump gasoline upward into a small tank located within the upper wing from which it flows by gravity to the engine carburetor. Information is given on the efficiency of the pump, the head resistance of the vanes, the performance and characteristics of the unit with and without housing about the vanes, the pump performance when motor driven, and resistance and power characteristics.

  14. 18. Electrically driven pumps in Armory Street Pump House. Pumps ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Electrically driven pumps in Armory Street Pump House. Pumps in background formerly drew water from the clear well. They went out of service when use of the beds was discontinued. Pumps in the foreground provide high pressure water to Hamden. - Lake Whitney Water Filtration Plant, Armory Street Pumphouse, North side of Armory Street between Edgehill Road & Whitney Avenue, Hamden, New Haven County, CT

  15. Subnanometer Motion of Cargoes Driven by Thermal Gradients Along Carbon Nanotubes

    NASA Astrophysics Data System (ADS)

    Barreiro, Amelia; Rurali, Riccardo; Hernández, Eduardo R.; Moser, Joel; Pichler, Thomas; Forró, László; Bachtold, Adrian

    2008-05-01

    An important issue in nanoelectromechanical systems is developing small electrically driven motors. We report on an artificial nanofabricated motor in which one short carbon nanotube moves relative to another coaxial nanotube. A cargo is attached to an ablated outer wall of a multiwalled carbon nanotube that can rotate and/or translate along the inner nanotube. The motion is actuated by imposing a thermal gradient along the nanotube, which allows for subnanometer displacements, as opposed to an electromigration or random walk effect.

  16. 46 CFR 153.1120 - Procedures for tank prewash: Categories A, B, and C.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... approved Procedures and Arrangements Manual for the prewash. (3) The wash water must be heated if required by § 153.1108, and water or tank washings must pass through the cargo pump and piping, including any... collected in the bottom of the tank for the pump to gain suction, and if the NLS is immiscible with water or...

  17. 46 CFR 153.1120 - Procedures for tank prewash: Categories A, B, and C.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... approved Procedures and Arrangements Manual for the prewash. (3) The wash water must be heated if required by § 153.1108, and water or tank washings must pass through the cargo pump and piping, including any... collected in the bottom of the tank for the pump to gain suction, and if the NLS is immiscible with water or...

  18. 46 CFR 153.1120 - Procedures for tank prewash: Categories A, B, and C.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... approved Procedures and Arrangements Manual for the prewash. (3) The wash water must be heated if required by § 153.1108, and water or tank washings must pass through the cargo pump and piping, including any... collected in the bottom of the tank for the pump to gain suction, and if the NLS is immiscible with water or...

  19. 46 CFR 153.1120 - Procedures for tank prewash: Categories A, B, and C.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... approved Procedures and Arrangements Manual for the prewash. (3) The wash water must be heated if required by § 153.1108, and water or tank washings must pass through the cargo pump and piping, including any... collected in the bottom of the tank for the pump to gain suction, and if the NLS is immiscible with water or...

  20. 46 CFR 153.1120 - Procedures for tank prewash: Categories A, B, and C.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... approved Procedures and Arrangements Manual for the prewash. (3) The wash water must be heated if required by § 153.1108, and water or tank washings must pass through the cargo pump and piping, including any... collected in the bottom of the tank for the pump to gain suction, and if the NLS is immiscible with water or...

  1. Gas-heat-pump development

    NASA Astrophysics Data System (ADS)

    Creswick, F. A.

    Incentives for the development of gas heat pumps are discussed. Technical progress made on several promising technologies was reviewed. The status of development of gas-engine-driven heat pumps, the absorption cycle for the near- and long-term gas heat pump systems, the Stirling engine, the small Rankine-cycle engines, and gas-turbine-driven heat pump systems were briefly reviewed. Progress in the US, Japan, and Europe is noted.

  2. 46 CFR 153.209 - Bilge pumping systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment General Vessel... spaces separated from cargo tanks by only a single bulkhead must be entirely within the locations allowed...

  3. 46 CFR 153.209 - Bilge pumping systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment General Vessel... spaces separated from cargo tanks by only a single bulkhead must be entirely within the locations allowed...

  4. 46 CFR 153.209 - Bilge pumping systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment General Vessel... spaces separated from cargo tanks by only a single bulkhead must be entirely within the locations allowed...

  5. 46 CFR 153.209 - Bilge pumping systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment General Vessel... spaces separated from cargo tanks by only a single bulkhead must be entirely within the locations allowed...

  6. 46 CFR 153.209 - Bilge pumping systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment General Vessel... spaces separated from cargo tanks by only a single bulkhead must be entirely within the locations allowed...

  7. 46 CFR 153.1040 - Carbon disulfide.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures... in § 35.01-1 of this chapter; or (2) The vapor space in the pump well is filled with water. ...

  8. 46 CFR 153.1040 - Carbon disulfide.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures... in § 35.01-1 of this chapter; or (2) The vapor space in the pump well is filled with water. ...

  9. 46 CFR 153.1040 - Carbon disulfide.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Operations Special Cargo Procedures... in § 35.01-1 of this chapter; or (2) The vapor space in the pump well is filled with water. ...

  10. A magnetically driven piston pump for ultra-clean applications

    NASA Astrophysics Data System (ADS)

    LePort, F.; Neilson, R.; Barbeau, P. S.; Barry, K.; Bartoszek, L.; Counts, I.; Davis, J.; deVoe, R.; Dolinski, M. J.; Gratta, G.; Green, M.; Díez, M. Montero; Müller, A. R.; O'Sullivan, K.; Rivas, A.; Twelker, K.; Aharmim, B.; Auger, M.; Belov, V.; Benitez-Medina, C.; Breidenbach, M.; Burenkov, A.; Cleveland, B.; Conley, R.; Cook, J.; Cook, S.; Craddock, W.; Daniels, T.; Dixit, M.; Dobi, A.; Donato, K.; Fairbank, W.; Farine, J.; Fierlinger, P.; Franco, D.; Giroux, G.; Gornea, R.; Graham, K.; Green, C.; Hägemann, C.; Hall, C.; Hall, K.; Hallman, D.; Hargrove, C.; Herrin, S.; Hughes, M.; Hodgson, J.; Juget, F.; Kaufman, L. J.; Karelin, A.; Ku, J.; Kuchenkov, A.; Kumar, K.; Leonard, D. S.; Lutter, G.; Mackay, D.; MacLellan, R.; Marino, M.; Mong, B.; Morgan, P.; Odian, A.; Piepke, A.; Pocar, A.; Prescott, C. Y.; Pushkin, K.; Rollin, E.; Rowson, P. C.; Schmoll, B.; Sinclair, D.; Skarpaas, K.; Slutsky, S.; Stekhanov, V.; Strickland, V.; Swift, M.; Vuilleumier, J.-L.; Vuilleumier, J.-M.; Wichoski, U.; Wodin, J.; Yang, L.; Yen, Y.-R.

    2011-10-01

    A magnetically driven piston pump for xenon gas recirculation is presented. The pump is designed to satisfy extreme purity and containment requirements, as is appropriate for the recirculation of isotopically enriched xenon through the purification system and large liquid xenon time projection chamber of EXO-200. The pump, using sprung polymer gaskets, is capable of pumping more than 16 standard liters per minute of xenon gas with 750 Torr differential pressure.

  11. A magnetically driven piston pump for ultra-clean applications.

    PubMed

    LePort, F; Neilson, R; Barbeau, P S; Barry, K; Bartoszek, L; Counts, I; Davis, J; deVoe, R; Dolinski, M J; Gratta, G; Green, M; Montero Díez, M; Müller, A R; O'Sullivan, K; Rivas, A; Twelker, K; Aharmim, B; Auger, M; Belov, V; Benitez-Medina, C; Breidenbach, M; Burenkov, A; Cleveland, B; Conley, R; Cook, J; Cook, S; Craddock, W; Daniels, T; Dixit, M; Dobi, A; Donato, K; Fairbank, W; Farine, J; Fierlinger, P; Franco, D; Giroux, G; Gornea, R; Graham, K; Green, C; Hägemann, C; Hall, C; Hall, K; Hallman, D; Hargrove, C; Herrin, S; Hughes, M; Hodgson, J; Juget, F; Kaufman, L J; Karelin, A; Ku, J; Kuchenkov, A; Kumar, K; Leonard, D S; Lutter, G; Mackay, D; MacLellan, R; Marino, M; Mong, B; Morgan, P; Odian, A; Piepke, A; Pocar, A; Prescott, C Y; Pushkin, K; Rollin, E; Rowson, P C; Schmoll, B; Sinclair, D; Skarpaas, K; Slutsky, S; Stekhanov, V; Strickland, V; Swift, M; Vuilleumier, J-L; Vuilleumier, J-M; Wichoski, U; Wodin, J; Yang, L; Yen, Y-R

    2011-10-01

    A magnetically driven piston pump for xenon gas recirculation is presented. The pump is designed to satisfy extreme purity and containment requirements, as is appropriate for the recirculation of isotopically enriched xenon through the purification system and large liquid xenon time projection chamber of EXO-200. The pump, using sprung polymer gaskets, is capable of pumping more than 16 standard liters per minute of xenon gas with 750 Torr differential pressure.

  12. Dustproofing Unsurfaced Areas: Facilities Technology Application Test (FTAT) Demonstration, FY 86.

    DTIC Science & Technology

    1987-08-01

    filtering systems, vehicle/aircraft turbines, and vehicle/aircraft cargo areas which increases wear and tear on the vehicles and aircraft. f. Dust... asphalt distributor, gravity-fed water truck, or any transportable liquid container tank with an external pump and spray bar or spray hose. Agitation...lubricants, providing an external lubrication system for certain types of pumps, such as that on an asphalt distributor, may be necessary. 20. A

  13. Water Permeation through the Sodium-Dependent Galactose Cotransporter vSGLT

    PubMed Central

    Choe, Seungho; Rosenberg, John M.; Abramson, Jeff; Wright, Ernest M.; Grabe, Michael

    2010-01-01

    It is well accepted that cotransporters facilitate water movement by two independent mechanisms: osmotic flow through a water channel in the protein and flow driven by ion/substrate cotransport. However, the molecular mechanism of transport-linked water flow is controversial. Some researchers believe that it occurs via cotransport, in which water is pumped along with the transported cargo, while others believe that flow is osmotic in response to an increase in intracellular osmolarity. In this letter, we report the results of a 200-ns molecular dynamics simulation of the sodium-dependent galactose cotransporter vSGLT. Our simulation shows that a significant number of water molecules cross the protein through the sugar-binding site in the presence as well as the absence of galactose, and 70–80 water molecules accompany galactose as it moves from the binding site into the intracellular space. During this event, the majority of water molecules in the pathway are unable to diffuse around the galactose, resulting in water in the inner half of the transporter being pushed into the intracellular space and replaced by extracellular water. Thus, our simulation supports the notion that cotransporters act as both passive water channels and active water pumps with the transported substrate acting as a piston to rectify the motion of water. PMID:20923633

  14. 46 CFR 56.50-30 - Boiler feed piping.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... pump may be used for other purposes. (2) If two independently driven pumps are provided, each capable... requirements. (1) Steam vessels, and motor vessels fitted with steam driven electrical generators shall have at... the necessary connections for this purpose. The arrangement of feed pumps shall be in accordance with...

  15. Chimeric microbial rhodopsins for optical activation of Gs-proteins

    PubMed Central

    Yoshida, Kazuho; Yamashita, Takahiro; Sasaki, Kengo; Inoue, Keiichi; Shichida, Yoshinori; Kandori, Hideki

    2017-01-01

    We previously showed that the chimeric proteins of microbial rhodopsins, such as light-driven proton pump bacteriorhodopsin (BR) and Gloeobacter rhodopsin (GR) that contain cytoplasmic loops of bovine rhodopsin, are able to activate Gt protein upon light absorption. These facts suggest similar protein structural changes in both the light-driven proton pump and animal rhodopsin. Here we report two trials to engineer chimeric rhodopsins, one for the inserted loop, and another for the microbial rhodopsin template. For the former, we successfully activated Gs protein by light through the incorporation of the cytoplasmic loop of β2-adrenergic receptor (β2AR). For the latter, we did not observe any G-protein activation for the light-driven sodium pump from Indibacter alkaliphilus (IndiR2) or a light-driven chloride pump halorhodopsin from Natronomonas pharaonis (NpHR), whereas the light-driven proton pump GR showed light-dependent G-protein activation. This fact suggests that a helix opening motion is common to G protein coupled receptor (GPCR) and GR, but not to IndiR2 and NpHR. Light-induced difference FTIR spectroscopy revealed similar structural changes between WT and the third loop chimera for each light-driven pump. A helical structural perturbation, which was largest for GR, was further enhanced in the chimera. We conclude that similar structural dynamics that occur on the cytoplasmic side of GPCR are needed to design chimeric microbial rhodopsins. PMID:29362703

  16. Cargos Rotate at Microtubule Intersections during Intracellular Trafficking.

    PubMed

    Gao, Yuan; Anthony, Stephen M; Yu, Yanqi; Yi, Yi; Yu, Yan

    2018-06-19

    Intracellular cargos are transported by molecular motors along actin and microtubules, but how their dynamics depends on the complex structure of the cytoskeletal network remains unclear. In this study, we investigated this longstanding question by measuring simultaneously the rotational and translational dynamics of cargos at microtubule intersections in living cells. We engineered two-faced particles that are fluorescent on one hemisphere and opaque on the other and used their optical anisotropy to report the rotation of cargos. We show that cargos undergo brief episodes of unidirectional and rapid rotation while pausing at microtubule intersections. Probability and amplitude of the cargo rotation depend on the geometry of the intersecting filaments. The cargo rotation is not random motion due to detachment from microtubules, as revealed by statistical analyses of the translational and rotational dynamics. Instead, it is an active rotation driven by motor proteins. Although cargos are known to pause at microtubule intersections, this study reveals a different dimension of dynamics at this seemingly static state and, more importantly, provides direct evidence showing the correlation between cargo rotation and the geometry of underlying microtubule intersections. Copyright © 2018 Biophysical Society. All rights reserved.

  17. 46 CFR 153.1600 - Equipment required for conducting the stripping quantity test.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS... container: (1) A wet vacuum. (2) A positive displacement pump. (3) An eductor with an air/water separator in...

  18. 46 CFR 153.1600 - Equipment required for conducting the stripping quantity test.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS... container: (1) A wet vacuum. (2) A positive displacement pump. (3) An eductor with an air/water separator in...

  19. 46 CFR 153.1600 - Equipment required for conducting the stripping quantity test.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS... container: (1) A wet vacuum. (2) A positive displacement pump. (3) An eductor with an air/water separator in...

  20. 46 CFR 153.1600 - Equipment required for conducting the stripping quantity test.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS... container: (1) A wet vacuum. (2) A positive displacement pump. (3) An eductor with an air/water separator in...

  1. Centrifugal Force Based Magnetic Micro-Pump Driven by Rotating Magnetic Fields

    NASA Astrophysics Data System (ADS)

    Kim, S. H.; Hashi, S.; Ishiyama, K.

    2011-01-01

    This paper presents a centrifugal force based magnetic micro-pump for the pumping of blood. Most blood pumps are driven by an electrical motor with wired control. To develop a wireless and battery-free blood pump, the proposed pump is controlled by external rotating magnetic fields with a synchronized impeller. Synchronization occurs because the rotor is divided into multi-stage impeller parts and NdFeB permanent magnet. Finally, liquid is discharged by the centrifugal force of multi-stage impeller. The proposed pump length is 30 mm long and19 mm in diameter which much smaller than currently pumps; however, its pumping ability satisfies the requirement for a blood pump. The maximum pressure is 120 mmHg and the maximum flow rate is 5000ml/min at 100 Hz. The advantage of the proposed pump is that the general mechanical problems of a normal blood pump are eliminated by the proposed driving mechanism.

  2. An analytical study of hybrid ejector/internal combustion engine-driven heat pumps

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murphy, R.W.

    1988-01-01

    Because ejectors can combine high reliability with low maintenance cost in a package requiring little capital investment, they may provide attractive heat pumping capability in situations where the importance of their inefficiencies is minimized. One such concept, a hybrid system in which an ejector driven by engine reject heat is used to increase the performance of an internal combustion engine-driven heat pump, was analyzed by modifying an existing ejector heat pump model and combining it with generic compressor and internal combustion engine models. Under the model assumptions for nominal cooling mode conditions, the results showed that hybrid systems could providemore » substantial performance augmentation/emdash/up to 17/percent/ increase in system coefficient of performance for a parallel arrangement of an enhanced ejector with the engine-driven compressor. 4 refs., 4 figs., 4 tabs.« less

  3. Characterization of an induced pressure pumping force for microfluidics

    NASA Astrophysics Data System (ADS)

    Jiang, Hai; Fan, Na; Peng, Bei; Weng, Xuan

    2017-05-01

    The electro-osmotic pumping and pressure-driven manipulation of fluids are considered as the most common strategies in microfluidic devices. However, both of them exhibit major disadvantages such as hard integration and high reagent consumption, and they are destructive methods for detection and photo bleaching. In this paper, an electric field-effect flow control approach, combining the electro-osmotic pumping force and the pressure-driven pumping force, was developed to generate the induced pressure-driven flow in a T-shaped microfluidic chip. Electro-osmotic flow between the T-intersection and two reservoirs was demonstrated, and it provided a stable, continuous, and electric field-free flow in the section of the microchannel without the electrodes. The velocity of the induced pressure-driven flow was linearly proportional to the applied voltages. Both numerical and experimental investigations were conducted to prove the concept, and the experimental results showed good agreement with the numerical simulations. In comparison to other induced pressure pumping methods, this approach can induce a high and controllable pressure drop in the electric field-free segment, subsequently causing an induced pressure-driven flow for transporting particles or biological cells. In addition, the generation of bubbles and the blocking of the microchannel are avoided.

  4. Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network

    PubMed Central

    Blank, Birgit; Maiser, Andreas; Emin, Derya; Prescher, Jens; Beck, Gisela; Kienzle, Christine; Bartnik, Kira; Habermann, Bianca; Pakdel, Mehrshad; Leonhardt, Heinrich; Lamb, Don C.

    2016-01-01

    Sorting and export of transmembrane cargoes and lysosomal hydrolases at the trans-Golgi network (TGN) are well understood. However, elucidation of the mechanism by which secretory cargoes are segregated for their release into the extracellular space remains a challenge. We have previously demonstrated that, in a reaction that requires Ca2+, the soluble TGN-resident protein Cab45 is necessary for the sorting of secretory cargoes at the TGN. Here, we report that Cab45 reversibly assembles into oligomers in the presence of Ca2+. These Cab45 oligomers specifically bind secretory proteins, such as COMP and LyzC, in a Ca2+-dependent manner in vitro. In intact cells, mutation of the Ca2+-binding sites in Cab45 impairs oligomerization, as well as COMP and LyzC sorting. Superresolution microscopy revealed that Cab45 colocalizes with secretory proteins and the TGN Ca2+ pump (SPCA1) in specific TGN microdomains. These findings reveal that Ca2+-dependent changes in Cab45 mediate sorting of specific cargo molecules at the TGN. PMID:27138253

  5. Development of a Compact Efficient Cooling Pump for Space Suit Life Support Systems

    NASA Technical Reports Server (NTRS)

    vanBoeyen, Roger W.; Reeh, Jonathan A.; Trevino, Luis

    2008-01-01

    With the increasing demands placed on extravehicular activity (EVA) for the International Space Station (ISS) assembly and maintenance, along with planned lunar and Martian missions, the need for increased human productivity and capability becomes ever more critical. This is most readily achieved by reduction in space suit weight and volume, and increased hardware reliability, durability, and operating lifetime. Considerable progress has been made with each successive generation of space suit design; from the Apollo A7L suit, to the current Shuttle Extravehicular Mobile Unit (EMU) suit, and the next generation Constellation Space Suit Element (CSSE). However, one area of space suit design which has continued to lag is the fluid pump used to drive the water cooling loop of the Primary Life Support System (PLSS). The two main types of fluid pumps typically used in space applications are rotodynamic pumps (pumping is achieved through a rotary vaned impeller) and displacement pumps (which includes rotary and diaphragm pumps). The rotating and moving parts found in the pumps and electric motor add significantly to the susceptibility to wear and friction, thermal mismatch, and complexity of the pumps. Electric motor-driven pumps capable of achieving high operational reliability are necessarily large, heavy, and energy inefficient. This report describes a development effort conducted for NASA by Lynntech, Inc., who recently demonstrated the feasibility of an electrochemically-driven fluid cooling pump. With no electric motor and minimal lightweight components, an electrochemically-driven pump is expected to be significantly smaller, lighter and achieve a longer life time than conventional rotodynamic and displacement pumps. By employing sulfonated polystyrene-based proton exchange membranes, rather than conventional Nafion membranes, a significant reduction in the actuator power consumption was demonstrated. It was also demonstrated that these membranes possess the necessary mechanical strength, durability, and temperature range for long life space operation. The preliminary design for a Phase II prototype pump compares very favorably to the fluid cooling pumps currently used in space suit portable life support systems (PLSS). Characteristics of the electrochemically-driven pump are described and the benefits of the technology as a replacement for electric motor pumps in mechanically pumped single-phase fluid loops (MPFLs) is discussed.

  6. Water permeation through the sodium-dependent galactose cotransporter vSGLT.

    PubMed

    Choe, Seungho; Rosenberg, John M; Abramson, Jeff; Wright, Ernest M; Grabe, Michael

    2010-10-06

    It is well accepted that cotransporters facilitate water movement by two independent mechanisms: osmotic flow through a water channel in the protein and flow driven by ion/substrate cotransport. However, the molecular mechanism of transport-linked water flow is controversial. Some researchers believe that it occurs via cotransport, in which water is pumped along with the transported cargo, while others believe that flow is osmotic in response to an increase in intracellular osmolarity. In this letter, we report the results of a 200-ns molecular dynamics simulation of the sodium-dependent galactose cotransporter vSGLT. Our simulation shows that a significant number of water molecules cross the protein through the sugar-binding site in the presence as well as the absence of galactose, and 70-80 water molecules accompany galactose as it moves from the binding site into the intracellular space. During this event, the majority of water molecules in the pathway are unable to diffuse around the galactose, resulting in water in the inner half of the transporter being pushed into the intracellular space and replaced by extracellular water. Thus, our simulation supports the notion that cotransporters act as both passive water channels and active water pumps with the transported substrate acting as a piston to rectify the motion of water. Copyright © 2010 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  7. Heat driven pulse pump

    NASA Technical Reports Server (NTRS)

    Benner, Steve M (Inventor); Martins, Mario S. (Inventor)

    2000-01-01

    A heat driven pulse pump includes a chamber having an inlet port, an outlet port, two check valves, a wick, and a heater. The chamber may include a plurality of grooves inside wall of the chamber. When heated within the chamber, a liquid to be pumped vaporizes and creates pressure head that expels the liquid through the outlet port. As liquid separating means, the wick, disposed within the chamber, is to allow, when saturated with the liquid, the passage of only liquid being forced by the pressure head in the chamber, preventing the vapor from exiting from the chamber through the outlet port. A plurality of grooves along the inside surface wall of the chamber can sustain the liquid, which is amount enough to produce vapor for the pressure head in the chamber. With only two simple moving parts, two check valves, the heat driven pulse pump can effectively function over the long lifetimes without maintenance or replacement. For continuous flow of the liquid to be pumped a plurality of pumps may be connected in parallel.

  8. Harnessing catalytic pumps for directional delivery of microparticles in microchambers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Das, Sambeeta; Shklyaev, Oleg E.; Altemose, Alicia

    The directed transport of microparticles in microfluidic devices is vital for efficient bioassays and fabrication of complex microstructures. There remains, but, a need for methods to propel and steer microscopic cargo that do not require modifying these particles. By using theory and experiments, we show that catalytic surface reactions can be used to deliver microparticle cargo to specified regions in microchambers. Here reagents diffuse from a gel reservoir and react with the catalyst-coated surface. Fluid density gradients due to the spatially varying reagent concentration induce a convective flow, which carries the suspended particles until the reagents are consumed. Consequently, themore » cargo is deposited around a specific position on the surface. The velocity and final peak location of the cargo can be tuned independently. And by increasing the local particle concentration, highly sensitive assays can be performed efficiently and rapidly. Moreover, the process can be repeated by introducing fresh reagent into the microchamber.« less

  9. Harnessing catalytic pumps for directional delivery of microparticles in microchambers

    DOE PAGES

    Das, Sambeeta; Shklyaev, Oleg E.; Altemose, Alicia; ...

    2017-02-17

    The directed transport of microparticles in microfluidic devices is vital for efficient bioassays and fabrication of complex microstructures. There remains, but, a need for methods to propel and steer microscopic cargo that do not require modifying these particles. By using theory and experiments, we show that catalytic surface reactions can be used to deliver microparticle cargo to specified regions in microchambers. Here reagents diffuse from a gel reservoir and react with the catalyst-coated surface. Fluid density gradients due to the spatially varying reagent concentration induce a convective flow, which carries the suspended particles until the reagents are consumed. Consequently, themore » cargo is deposited around a specific position on the surface. The velocity and final peak location of the cargo can be tuned independently. And by increasing the local particle concentration, highly sensitive assays can be performed efficiently and rapidly. Moreover, the process can be repeated by introducing fresh reagent into the microchamber.« less

  10. Development of a Compact, Efficient Cooling Pump for Space Suit Life Support Systems

    NASA Technical Reports Server (NTRS)

    van Boeyen, Roger; Reeh, Jonathan; Trevino, Luis

    2009-01-01

    A compact, low-power electrochemically-driven fluid cooling pump is currently being developed by Lynntech, Inc. With no electric motor and minimal lightweight components, the pump is significantly lighter than conventional rotodynamic and displacement pumps. Reliability and robustness is achieved with the absence of rotating or moving components (apart from the bellows). By employing sulfonated polystyrene-based proton exchange membranes, rather than conventional Nafion membranes, a significant reduction in the actuator power consumption was demonstrated. Lynntech also demonstrated that these membranes possess the necessary mechanical strength, durability, and temperature range for long life space operation. The preliminary design for a Phase II prototype pump compares very favorably to the fluid cooling pumps currently used in space suit primary life support systems (PLSSs). Characteristics of the electrochemically-driven pump are described and the benefits of the technology as a replacement for electric motor pumps in mechanically pumped single-phase fluid loops is discussed.

  11. The Evolution of Ion Pumps.

    ERIC Educational Resources Information Center

    Maloney, Peter C.; Wilson, T. Hastings

    1985-01-01

    Constructs an evolutionary sequence to account for the diversity of ion pumps found today. Explanations include primary ion pumps in bacteria, features and distribution of ATP-driven pumps, preference for cation transport, and proton pump reversal. The integrated evolutionary hypothesis should encourage new experimental approaches. (DH)

  12. 46 CFR 38.20-10 - Ventilation-T/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... space surrounding tanks whose manhole openings are below the weather deck in accordance with § 38.05-10... containing pumps, compressors, pipes, control spaces, etc. connected with the cargo handling facilities... located at points where concentrations of vapors may be expected. Ventilation from the weather deck shall...

  13. 46 CFR 38.20-10 - Ventilation-T/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... space surrounding tanks whose manhole openings are below the weather deck in accordance with § 38.05-10... containing pumps, compressors, pipes, control spaces, etc. connected with the cargo handling facilities... located at points where concentrations of vapors may be expected. Ventilation from the weather deck shall...

  14. 46 CFR 38.20-10 - Ventilation-T/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... space surrounding tanks whose manhole openings are below the weather deck in accordance with § 38.05-10... containing pumps, compressors, pipes, control spaces, etc. connected with the cargo handling facilities... located at points where concentrations of vapors may be expected. Ventilation from the weather deck shall...

  15. 46 CFR 38.20-10 - Ventilation-T/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... space surrounding tanks whose manhole openings are below the weather deck in accordance with § 38.05-10... containing pumps, compressors, pipes, control spaces, etc. connected with the cargo handling facilities... located at points where concentrations of vapors may be expected. Ventilation from the weather deck shall...

  16. Fluid driven reciprocating apparatus

    DOEpatents

    Whitehead, J.C.

    1997-04-01

    An apparatus is described comprising a pair of fluid driven pump assemblies in a back-to-back configuration to yield a bi-directional pump. Each of the pump assemblies includes a piston or diaphragm which divides a chamber therein to define a power section and a pumping section. An intake-exhaust valve is connected to each of the power sections of the pump chambers, and function to direct fluid, such as compressed air, into the power section and exhaust fluid therefrom. At least one of the pistons or diaphragms is connected by a rod assembly which is constructed to define a signal valve, whereby the intake-exhaust valve of one pump assembly is controlled by the position or location of the piston or diaphragm in the other pump assembly through the operation of the rod assembly signal valve. Each of the pumping sections of the pump assemblies are provided with intake and exhaust valves to enable filling of the pumping section with fluid and discharging fluid therefrom when a desired pressure has been reached. 13 figs.

  17. Fluid driven recipricating apparatus

    DOEpatents

    Whitehead, John C.

    1997-01-01

    An apparatus comprising a pair of fluid driven pump assemblies in a back-to-back configuration to yield a bi-directional pump. Each of the pump assemblies includes a piston or diaphragm which divides a chamber therein to define a power section and a pumping section. An intake-exhaust valve is connected to each of the power sections of the pump chambers, and function to direct fluid, such as compressed air, into the power section and exhaust fluid therefrom. At least one of the pistons or diaphragms is connected by a rod assembly which is constructed to define a signal valve, whereby the intake-exhaust valve of one pump assembly is controlled by the position or location of the piston or diaphragm in the other pump assembly through the operation of the rod assembly signal valve. Each of the pumping sections of the pump assemblies are provided with intake and exhaust valves to enable filling of the pumping section with fluid and discharging fluid therefrom when a desired pressure has been reached.

  18. Coupling of active motion and advection shapes intracellular cargo transport.

    PubMed

    Khuc Trong, Philipp; Guck, Jochen; Goldstein, Raymond E

    2012-07-13

    Intracellular cargo transport can arise from passive diffusion, active motor-driven transport along cytoskeletal filament networks, and passive advection by fluid flows entrained by such cargo-motor motion. Active and advective transport are thus intrinsically coupled as related, yet different representations of the same underlying network structure. A reaction-advection-diffusion system is used here to show that this coupling affects the transport and localization of a passive tracer in a confined geometry. For sufficiently low diffusion, cargo localization to a target zone is optimized either by low reaction kinetics and decoupling of bound and unbound states, or by a mostly disordered cytoskeletal network with only weak directional bias. These generic results may help to rationalize subtle features of cytoskeletal networks, for example as observed for microtubules in fly oocytes.

  19. How neurosecretory vesicles release their cargo.

    PubMed

    Scalettar, Bethe A

    2006-04-01

    Neurons and related cell types often contain two major classes of neurosecretory vesicles, synaptic vesicles (SVs) and dense-core granules (DCGs), which store and release distinct cargo. SVs store and release classic neurotransmitters, which facilitate propagation of action potentials across the synaptic cleft, whereas DCGs transport, store, and release hormones, proteins, and neuropeptides, which facilitate neuronal survival, synaptic transmission, and learning. Over the past few years, there has been a major surge in our understanding of many of the key molecular mechanisms underlying cargo release from SVs and DCGs. This surge has been driven largely by the use of fluorescence microscopy (especially total internal reflection fluorescence microscopy) to visualize SVs or DCGs in living cells. This review highlights some of the recent insights into cargo release from neurosecretory vesicles provided by fluorescence microscopy, with emphasis on DCGs.

  20. Pilot Field Demonstration of Alternative Fuels in Force Projection Petroleum and Water Distribution Equipment

    DTIC Science & Technology

    2014-09-04

    They included two Force Projection Technology (FPT) diesel driven pumping assemblies of 350 and 600 gallons per minute (GPM), and the Advanced...Army Tank Automotive Research Development and Engineering Center (TARDEC). They included two Force Projection Technology (FPT) diesel driven...research programs. The first two systems identified were Force Projection Technology (FPT) diesel -driven pumping assemblies of 350 and 600 gallons per

  1. 46 CFR 131.340 - Recommended placard for emergency instructions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Keep bilges dry to prevent loss of stability from water in bilges. Use power-driven bilge pump, hand pump, and buckets to dewater. (3) Align fire pumps to serve as bilge pumps if possible. (4) Check, for...

  2. 46 CFR 131.340 - Recommended placard for emergency instructions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Keep bilges dry to prevent loss of stability from water in bilges. Use power-driven bilge pump, hand pump, and buckets to dewater. (3) Align fire pumps to serve as bilge pumps if possible. (4) Check, for...

  3. 46 CFR 131.340 - Recommended placard for emergency instructions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Keep bilges dry to prevent loss of stability from water in bilges. Use power-driven bilge pump, hand pump, and buckets to dewater. (3) Align fire pumps to serve as bilge pumps if possible. (4) Check, for...

  4. 46 CFR 122.512 - Recommended emergency instructions format.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... in the vessel. (ii) Keep bilges dry to prevent loss of stability due to water in bilges. Use power driven bilge pump, hand pump, and buckets to dewater. (iii) Align fire pumps to use as bilge pump if...

  5. 46 CFR 122.512 - Recommended emergency instructions format.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... in the vessel. (ii) Keep bilges dry to prevent loss of stability due to water in bilges. Use power driven bilge pump, hand pump, and buckets to dewater. (iii) Align fire pumps to use as bilge pump if...

  6. 46 CFR 122.512 - Recommended emergency instructions format.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... in the vessel. (ii) Keep bilges dry to prevent loss of stability due to water in bilges. Use power driven bilge pump, hand pump, and buckets to dewater. (iii) Align fire pumps to use as bilge pump if...

  7. 46 CFR 167.30-10 - Special operating requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., (3) Within or on the boundaries of fuel tanks; or, (4) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections shall be made and... SCHOOL SHIPS Repairs or Alterations § 167.30-10 Special operating requirements. Inspection and testing...

  8. 46 CFR 167.30-10 - Special operating requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., (3) Within or on the boundaries of fuel tanks; or, (4) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections shall be made and... SCHOOL SHIPS Repairs or Alterations § 167.30-10 Special operating requirements. Inspection and testing...

  9. 46 CFR 167.30-10 - Special operating requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., (3) Within or on the boundaries of fuel tanks; or, (4) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections shall be made and... SCHOOL SHIPS Repairs or Alterations § 167.30-10 Special operating requirements. Inspection and testing...

  10. 46 CFR 167.30-10 - Special operating requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., (3) Within or on the boundaries of fuel tanks; or, (4) To pipe lines, heating coils, pumps, fittings, or other appurtenances connected to such cargo or fuel tanks. (c) Such inspections shall be made and... SCHOOL SHIPS Repairs or Alterations § 167.30-10 Special operating requirements. Inspection and testing...

  11. 46 CFR 151.45-2 - Special operating requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... cargo into the water, voids, or cofferdams nor leaks water into the tanks, voids, or cofferdams; (ii... ballasting) substantially free of water. Periodic inspections and necessary pumping shall be carried out to insure maintenance of such water-free condition in order to minimize the free surface effects, both in...

  12. 33 CFR 104.270 - Security measures for restricted areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... surveillance equipment and systems and their controls and lighting system controls; (3) Ventilation and air-conditioning systems and other similar spaces; (4) Spaces with access to potable water tanks, pumps, or... security and surveillance equipment and systems; and (6) Protect cargo and vessel stores from tampering. (b...

  13. Reiter during maintenance tasks in the FGB

    NASA Image and Video Library

    2006-08-10

    ISS013-E-65721 (10 Aug. 2006) --- European Space Agency (ESA) astronaut Thomas Reiter, Expedition 13 flight engineer, replaces the number two replaceable pump panel (SPN) in the number one loop (VGK1) of the International Space Station's Zarya functional cargo block (FGB) thermal control system with a new spare from stowage.

  14. 46 CFR 28.840 - Means for stopping pumps, ventilation, and machinery.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... pumps, ventilation, and machinery. All electrically driven fuel oil transfer pumps, fuel oil unit and service pumps, and ventilation fans shall be fitted with remote controls from a readily accessible... 46 Shipping 1 2014-10-01 2014-10-01 false Means for stopping pumps, ventilation, and machinery. 28...

  15. 46 CFR 28.840 - Means for stopping pumps, ventilation, and machinery.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... pumps, ventilation, and machinery. All electrically driven fuel oil transfer pumps, fuel oil unit and service pumps, and ventilation fans shall be fitted with remote controls from a readily accessible... 46 Shipping 1 2010-10-01 2010-10-01 false Means for stopping pumps, ventilation, and machinery. 28...

  16. 46 CFR 28.840 - Means for stopping pumps, ventilation, and machinery.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... pumps, ventilation, and machinery. All electrically driven fuel oil transfer pumps, fuel oil unit and service pumps, and ventilation fans shall be fitted with remote controls from a readily accessible... 46 Shipping 1 2013-10-01 2013-10-01 false Means for stopping pumps, ventilation, and machinery. 28...

  17. 46 CFR 28.840 - Means for stopping pumps, ventilation, and machinery.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... pumps, ventilation, and machinery. All electrically driven fuel oil transfer pumps, fuel oil unit and service pumps, and ventilation fans shall be fitted with remote controls from a readily accessible... 46 Shipping 1 2012-10-01 2012-10-01 false Means for stopping pumps, ventilation, and machinery. 28...

  18. 46 CFR 28.840 - Means for stopping pumps, ventilation, and machinery.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... pumps, ventilation, and machinery. All electrically driven fuel oil transfer pumps, fuel oil unit and service pumps, and ventilation fans shall be fitted with remote controls from a readily accessible... 46 Shipping 1 2011-10-01 2011-10-01 false Means for stopping pumps, ventilation, and machinery. 28...

  19. Fuel system for rotary distributor fuel injection pump

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klopfer, K.H.; Kelly, W.W.

    1993-06-01

    In a fuel injection pump having a drive shaft, a pump rotor driven by the drive shaft, reciprocating pumping means with periodic intake and pumping strokes to periodically receive an intake charge of fuel and deliver fuel at high pressure for fuel injection is described; a distributor head with a plurality of angularly spaced distributor outlets, the pump rotor providing a distributor rotor with a distributor port connected to the pumping means, the distributor rotor being rotatably mounted in the distributor head for sequential registration of the distributor port with the distributor outlets for distributing said high pressure delivery ofmore » fuel thereto; a fuel system for supplying fuel to the pumping means, having an end chamber at one end of the pump rotor and a fuel supply pump driven by the drive shaft and having an inlet and outlet, the supply pump outlet being connected to the end chamber for supplying fuel thereto, and a pressure regulator for regulating the fuel pressure in the end chamber; and a control valve connected between the pumping means and the end chamber and selectively opened during the intake strokes to supply fuel to the pumping means from the end chamber and during the pumping strokes to spill fuel from the pumping means into the end chamber to terminate said high pressure delivery of fuel; the improvement wherein the fuel system comprises a fuel return passage connected in series with the end chamber downstream thereof, wherein the pressure regulator is mounted in the return passage for regulating the upstream fuel pressure, including the upstream fuel pressure within the end chamber, and is connected for conducting excess fuel for return to the supply pump inlet, and wherein the supply pump is driven by the drive shaft to supply fuel at a rate exceeding the rate of said high pressure delivery of fuel for fuel injection and to provide excess fuel flow continuously through the end chamber and return passage to the pressure regulator.« less

  20. Enzyme-Powered Pumps: From Fundamentals to Applications

    NASA Astrophysics Data System (ADS)

    Ortiz-Rivera, Isamar

    Non-mechanical nano and microfluidic devices that function without the aid of an external power source, and can be tailored to meet specific needs, represent the next generation of smart devices. Recently, we have shown that surface-bound enzymes can act as pumps driving large-scale fluid flows in the presence of any substance that triggers the enzymatic reaction (e.g. substrate, co-factor, or biomarker). The fluid velocities attained in such systems depend directly on the enzymatic reaction rate and the concentration of the substance that initiates enzymatic catalysis. The use of biochemical reactions to power a micropump offers the advantages of specificity, sensitivity, and selectively, eliminating at the same time the need of an external power source, while providing biocompatibility. More importantly, these self-powered pumps overcome a significant obstacle in nano- and micro-fluidics: the need to use external pressure-driven pumps to push fluids through devices. Certainly, the development of enzyme-powered devices opens up new venues in biochemical engineering, particularly in the biomedical field. The work highlighted in this dissertation covers all the studies performed with enzyme-powered pumps, from the development of the micropump design, to the efforts invested in understanding the enzyme pump concept as a whole. The data collected to date, aims to expand our knowledge about enzyme-powered micropumps from the inside out: not only by exploring the different applications of these devices at the macroscale, but also by investigating in depth the mechanism of pump activation behind these systems. Specifically, we have focused on: (1) The general features that characterize the pumping behavior observed in enzyme-powered pumps, as well as the optimization of the device, (2) the possible mechanisms behind fluid motion, including the role of enzyme coverage and/or activity on the transduction of chemical energy into mechanical fluid flow in these devices, covering also the effect of the thermodynamics of the enzymatic reaction in the pumping behavior, and (3) the applicability of enzyme pumps as fluid flow-based inhibitor assays and as drug delivery devices. Our findings in each of these areas, gets us closer to our ultimate goal, where we aim to identify the optimal conditions needed for enzyme micropump operation, and construct a general model that could accurately predict enzyme micropump behavior for any enzyme-substrate combination. The information aforementioned has been divided in four chapters. Chapter 1 gives a quick glance into the development of enzyme-powered micropumps: from the systems and observed behaviors inspiring this work, to the first systems that were developed. The stability, duration, and extent of fluid pumping of enzyme pumps in general, are also discussed, along with the optimization of the enzyme-pump design. This chapter aims to provide a general idea of the motivation behind the concept of "enzyme-powered pumps", what are "enzyme-powered pumps", and which are the key features that characterize these systems. Chapter 2 is an extensive analysis of the mechanisms of actuation proposed for enzyme-powered micropumps. This chapter not only covers the first attempts to understand how enzyme pumps work, but also explores further the behavior of urease-powered pumps, which fluid flow patterns cannot be completely predicted only by considering thermal or solutal gradients. The findings of these studies could allow us to rationally control fluid flow for the directed delivery of payloads at designated locations. In Chapters 3 and 4, our focus was to highlight the potential application of enzyme-powered pumps for sensing and delivery. Chapter 3 explores the use of enzyme pumps as fluid flow-based inhibitor assays. At fixed concentrations of an enzyme and its substrate, the presence of an inhibitor can be detected by monitoring the decrease in fluid flow speed. Using this principle, sensors for toxic substances, like mercury, cyanide and azide, were designed using urease and catalase-powered pumps, respectively, with limits of detection well below the concentrations permitted by the Environmental Protection Agency (EPA). Chapter 4 demonstrates that, apart from their applicability as sensors, enzyme pumps can also be used for stimuli-responsive release, if the architecture applied for the design of the enzyme pump consists of a porous scaffold (e.g. hydrogel), that serves both as the platform for enzyme immobilization and as the host for guest molecules to be released. These proof-of-concept devices were developed with the idea of using the flows generated by enzymatic catalysis to power cargo release, only in the presence of the correct stimuli (e.g. release of insulin in the presence of glucose; release of antidotes in the presence of a toxic agent). In the cases studied, cargo release was directly proportional to the concentration of enzyme substrate in solution, highlighting the sensitivity of the device and its potential for drug delivery purposes. (Abstract shortened by Proquest.).

  1. Drive the Car(go)s-New Modalities to Control Cargo Trafficking in Live Cells.

    PubMed

    Mondal, Payel; Khamo, John S; Krishnamurthy, Vishnu V; Cai, Qi; Zhang, Kai

    2017-01-01

    Synaptic transmission is a fundamental molecular process underlying learning and memory. Successful synaptic transmission involves coupled interaction between electrical signals (action potentials) and chemical signals (neurotransmitters). Defective synaptic transmission has been reported in a variety of neurological disorders such as Autism and Alzheimer's disease. A large variety of macromolecules and organelles are enriched near functional synapses. Although a portion of macromolecules can be produced locally at the synapse, a large number of synaptic components especially the membrane-bound receptors and peptide neurotransmitters require active transport machinery to reach their sites of action. This spatial relocation is mediated by energy-consuming, motor protein-driven cargo trafficking. Properly regulated cargo trafficking is of fundamental importance to neuronal functions, including synaptic transmission. In this review, we discuss the molecular machinery of cargo trafficking with emphasis on new experimental strategies that enable direct modulation of cargo trafficking in live cells. These strategies promise to provide insights into a quantitative understanding of cargo trafficking, which could lead to new intervention strategies for the treatment of neurological diseases.

  2. KSC-2009-2238

    NASA Image and Video Library

    2009-03-21

    CAPE CANAVERAL, Fla. – A C-17 cargo plane arrives at the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida with its cargo of the EXPRESS Logistics Carrier for the STS-129 mission. In the background is the mate/demate device used to separate a space shuttle from the Shuttle Carrier Aircraft. The carrier is part of the payload on space shuttle Atlantis, which will deliver to the International Space Station components including two spare gyroscopes, two nitrogen tank assemblies, two pump modules, an ammonia tank assembly and a spare latching end effector for the station's robotic arm. STS-129 is targeted to launch Nov. 12. Photo credit: NASA/Tim Jacobs

  3. A study on various methods of supplying propellant to an orbit insertion rocket engine

    NASA Technical Reports Server (NTRS)

    Boretz, J. E.; Huniu, S.; Thompson, M.; Pagani, M.; Paulsen, B.; Lewis, J.; Paul, D.

    1980-01-01

    Various types of pumps and pump drives were evaluated to determine the lightest weight system for supplying propellants to a planetary orbit insertion rocket engine. From these analyses four candidate propellant feed systems were identified. Systems Nos. 1 and 2 were both battery powered (lithium-thionyl-chloride or silver-zinc) motor driven pumps. System 3 was a monopropellant gas generator powered turbopump. System 4 was a bipropellant gas generator powered turbopump. Parameters considered were pump break horsepower, weight, reliability, transient response and system stability. Figures of merit were established and the ranking of the candidate systems was determined. Conceptual designs were prepared for typical motor driven pumps and turbopump configurations for a 1000 lbf thrust rocket engine.

  4. Development of a miniature motor-driven pulsatile LVAD driven by a fuzzy controller.

    PubMed

    Okamoto, Eiji; Makino, Tsutomu; Tanaka, Shuji; Yasuda, Takahiko; Akasaka, Yuta; Tani, Makiko; Inoue, Yusuke; Mitoh, Ayumu; Mitamura, Yoshinori

    2007-01-01

    We have been developing a small, lightweight motor-driven pulsatile left ventricular assist device (LVAD) with a ball screw. The motor-driven LVAD consists of a brushless DC motor and a ball screw. The attractive magnetic force between Nd-Fe-B magnets (with a diameter of 5 mm and a thickness of 1.5 mm) mounted in holes in a silicone rubber sheet (thickness 2 mm) and an iron plate adhered onto the a diaphragm of the blood pump can provide optimum active blood filling during the pump filling phase. The LVAD has a stroke volume of 55 ml and an overall volume of 285 ml; it weighs 360 g. The controller mainly consists of a fuzzy logic position and velocity controller to apply doctors' and engineers' knowledge to control the LVAD. Each unit of the controller consists of a functionally independent program module for easy improvement of the controller's performance. The LVAD was evaluated in in vitro experiments using a mock circulation. A maximum pump outflow of 5.1 l/min was obtained at a drive rate of 95 bpm against an afterload of 95 mmHg, and active filling using the attractive magnetic force provided a pump output of 3.6 l/min at a drive rate of 75 bpm under a preload of 0 mmHg. The operating efficiency of the LVAD was measured at between 8% and 10.5%. While the LVAD can provide adequate pump outflow for cardiac assistance, further upgrading of the software and improvement of the blood pump are required to improve pump performance and efficiency.

  5. Microemulsion-Based Soft Bacteria-Driven Microswimmers for Active Cargo Delivery.

    PubMed

    Singh, Ajay Vikram; Hosseinidoust, Zeinab; Park, Byung-Wook; Yasa, Oncay; Sitti, Metin

    2017-10-24

    Biohybrid cell-driven microsystems offer unparalleled possibilities for realization of soft microrobots at the micron scale. Here, we introduce a bacteria-driven microswimmer that combines the active locomotion and sensing capabilities of bacteria with the desirable encapsulation and viscoelastic properties of a soft double-micelle microemulsion for active transport and delivery of cargo (e.g., imaging agents, genes, and drugs) to living cells. Quasi-monodisperse double emulsions were synthesized with an aqueous core that encapsulated the fluorescence imaging agents, as a proof-of-concept cargo in this study, and an outer oil shell that was functionalized with streptavidin for specific and stable attachment of biotin-conjugated Escherichia coli. Motile bacteria effectively propelled the soft microswimmers across a Transwell membrane, actively delivering imaging agents (i.e., dyes) encapsulated inside of the micelles to a monolayer of cultured MCF7 breast cancer and J744A.1 macrophage cells, which enabled real-time, live-cell imaging of cell organelles, namely mitochondria, endoplasmic reticulum, and Golgi body. This in vitro model demonstrates the proof-of-concept feasibility of the proposed soft microswimmers and offers promise for potential biomedical applications in active and/or targeted transport and delivery of imaging agents, drugs, stem cells, siRNA, and therapeutic genes to live tissue in in vitro disease models (e.g., organ-on-a-chip devices) and stagnant or low-flow-velocity fluidic regions of the human body.

  6. Design and feasibility study for a portable oil recovery turbopump

    NASA Technical Reports Server (NTRS)

    1982-01-01

    A portable oil recovery turbopump concept, using the Firefly module as primer mover, for the offloading of distressed tank vessels is examined. The demands to be met both in terms of the type of petroleum to be offloaded, as well as the operational requirements placed on the pump, are studied with respect to the capability of different pump configurations. Two configurations, one a centrifugal type and the other a screw type pump, are developed and evaluated. While the centrifugal configuration is found to be effective in a large proportion of tank vessel offloading situations, the screw type will be required where high viscosity cargoes are involved. The feasibility of the turbopump concept, with the Firefly module as prime mover, is established.

  7. An evaluation of a hubless inducer and a full flow hydraulic turbine driven inducer boost pump

    NASA Technical Reports Server (NTRS)

    Lindley, B. K.; Martinson, A. R.

    1971-01-01

    The purpose of the study was to compare the performance of several configurations of hubless inducers with a hydrodynamically similar conventional inducer and to demonstrate the performance of a full flow hydraulic turbine driven inducer boost pump using these inducers. A boost pump of this type consists of an inducer connected to a hydraulic turbine with a high speed rotor located in between. All the flow passes through the inducer, rotor, and hydraulic turbine, then into the main pump. The rotor, which is attached to the main pump shaft, provides the input power to drive the hydraulic turbine which, in turn, drives the inducer. The inducer, rotating at a lower speed, develops the necessary head to prevent rotor cavitation. The rotor speed is consistent with present main engine liquid hydrogen pump designs and the overall boost pump head rise is sufficient to provide adequate main pump suction head. This system would have the potential for operating at lower liquid hydrogen tank pressures.

  8. 46 CFR 56.97-40 - Installation tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) and 56.50-40(b), respectively. (2) Fuel oil discharge piping between the pumps and the burners, but.... (5) Any Class I, I-L, II-L piping. (6) Cargo oil piping. (7) Firemains, but not less than 150 pounds per square inch. (8) Fuel oil transfer and filling piping. (9) Class I compressed air piping. (10...

  9. Effect of fuel concentration on cargo transport by a team of Kinesin motors

    NASA Astrophysics Data System (ADS)

    Takshak, Anjneya; Mishra, Nirvantosh; Kulkarni, Aditi; Kunwar, Ambarish

    2017-02-01

    Eukaryotic cells employ specialized proteins called molecular motors for transporting organelles and vesicles from one location to another in a regulated and directed manner. These molecular motors often work collectively in a team while transporting cargos. Molecular motors use cytoplasmic ATP as fuel, which is hydrolyzed to generate mechanical force. While the effect of ATP concentration on cargo transport by single Kinesin motor function is well understood, it is still unexplored, both theoretically and experimentally, how ATP concentration would affect cargo transport by a team of Kinesin motors. For instance, how does fuel concentration affect the travel distances and travel velocities of cargo? How cooperativity of Kinesin motors engaged on a cargo is affected by ATP concentration? To answer these questions, here we develop mechano-chemical models of cargo transport by a team of Kinesin motors. To develop these models we use experimentally-constrained mechano-chemical model of a single Kinesin motor as well as earlier developed mean-field and stochastic models of load sharing for cargo transport. Thus, our new models for cargo transport by a team of Kinesin motors include fuel concentration explicitly, which was not considered in earlier models. We make several interesting predictions which can be tested experimentally. For instance, the travel distances of cargos are very large at limited ATP concentrations in spite of very small travel velocity. Velocities of cargos driven by multiple Kinesin have a Michaelis-Menten dependence on ATP concentration. Similarly, cooperativity among the engaged Kinesin motors on the cargo shows a Michaelis-Menten type dependence, which attains a maximum value near physiological ATP concentrations. Our new results can be potentially useful in controlling artificial nano-molecular shuttles precisely for targeted delivery in various nano-technological applications.

  10. 46 CFR 185.512 - Recommended emergency instructions format.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... in bilges. Use power driven bilge pump, hand pump, and buckets to dewater. (iii) Align fire pumps to... fixed extinguishing system if installed. (v) Maneuver vessel to minimize effect of wind on fire. (vi) If...

  11. Hourly simulation of a Ground-Coupled Heat Pump system

    NASA Astrophysics Data System (ADS)

    Naldi, C.; Zanchini, E.

    2017-01-01

    In this paper, we present a MATLAB code for the hourly simulation of a whole Ground-Coupled Heat Pump (GCHP) system, based on the g-functions previously obtained by Zanchini and Lazzari. The code applies both to on-off heat pumps and to inverter-driven ones. It is employed to analyse the effects of the inverter and of the total length of the Borehole Heat Exchanger (BHE) field on the mean seasonal COP (SCOP) and on the mean seasonal EER (SEER) of a GCHP system designed for a residential house with 6 apartments in Bologna, North-Center Italy, with dominant heating loads. A BHE field with 3 in line boreholes is considered, with length of each BHE either 75 m or 105 m. The results show that the increase of the BHE length yields a SCOP enhancement of about 7%, while the SEER remains nearly unchanged. The replacement of the on-off heat pump by an inverter-driven one yields a SCOP enhancement of about 30% and a SEER enhancement of about 50%. The results demonstrate the importance of employing inverter-driven heat pumps for GCHP systems.

  12. 46 CFR 28.265 - Emergency instructions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Describe your vessel: (Insert length, color, hull type, trim, masts, power, and any additional... the vessel. (ii) Keep bilges dry to prevent loss of stability due to water in bilges. Use power driven bilge pump, hand pump, and buckets to dewater. (iii) Align fire pumps to use as bilge pumps, if possible...

  13. 46 CFR 28.265 - Emergency instructions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Describe your vessel: (Insert length, color, hull type, trim, masts, power, and any additional... the vessel. (ii) Keep bilges dry to prevent loss of stability due to water in bilges. Use power driven bilge pump, hand pump, and buckets to dewater. (iii) Align fire pumps to use as bilge pumps, if possible...

  14. 46 CFR 28.265 - Emergency instructions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Describe your vessel: (Insert length, color, hull type, trim, masts, power, and any additional... the vessel. (ii) Keep bilges dry to prevent loss of stability due to water in bilges. Use power driven bilge pump, hand pump, and buckets to dewater. (iii) Align fire pumps to use as bilge pumps, if possible...

  15. 46 CFR 181.300 - Fire pumps.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Fire pumps. 181.300 Section 181.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) FIRE PROTECTION EQUIPMENT Fire Main System § 181.300 Fire pumps. (a) A self priming, power driven fire pump must be...

  16. 46 CFR 181.300 - Fire pumps.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Fire pumps. 181.300 Section 181.300 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) FIRE PROTECTION EQUIPMENT Fire Main System § 181.300 Fire pumps. (a) A self priming, power driven fire pump must be...

  17. Geothermal energy control system and method

    DOEpatents

    Matthews, Hugh B.

    1976-01-01

    A geothermal energy transfer and utilization system makes use of thermal energy stored in hot solute-bearing well water to generate super-heated steam from an injected flow of clean water; the super-heated steam is then used for operating a turbine-driven pump at the well bottom for pumping the hot solute-bearing water at high pressure and in liquid state to the earth's surface, where it is used by transfer of its heat to a closed-loop boiler-turbine-alternator combination for the generation of electrical or other power. Residual concentrated solute-bearing water is pumped back into the earth. The clean cooled water is regenerated at the surface-located system and is returned to the deep well pumping system also for lubrication of a novel bearing arrangement supporting the turbine-driven pump system.

  18. GSK-3 regulates transport of kinesin-1 driven cargos in vivo

    NASA Astrophysics Data System (ADS)

    Leidel, Christina; Weaver, Carole; Szpankowski, Lukasz; Goldstein, Lawrence S. B.; Shubeita, George T.; CenterNonlinear Dynamics, Department of Physics, University of Texas At Austin Collaboration; Hhmi, Department of Cellular; Molecular Medicine, Univ. Of California Collaboration

    2011-03-01

    The Glycogen Synthase Kinase 3 (GSK-3) has been linked to many aspects of the development of Alzheimer's disease and was proposed to play a role in the transport of the Amyloid Precursor Protein (APP) by kinesin-1 motors. Using Drosophila embryos and larvae with altered GSK-3 expression, we characterize motor transport of cargos including APP and lipid droplets using DIC microscopy, high-resolution video tracking, fluorescence, and in vivo stall force measurements with optical tweezers. By comparing cargo velocities and run lengths we find that GSK-3 is a required negative regulator of in vivo transport. Stall force measurements on lipid droplets reveal that enhanced transport under conditions of reduced GSK-3 is a result of a larger number of active motors hauling the cargo. Our findings have implications on the use of GSK-3 inhibitors in treatment of Alzheimer's disease.

  19. A Hopping Mechanism for Cargo Transport by Molecular Motors on Crowded Microtubules

    NASA Astrophysics Data System (ADS)

    Goldman, Carla

    2010-05-01

    Most models designed to study the bidirectional movement of cargos as they are driven by molecular motors rely on the idea that motors of different polarities can be coordinated by external agents if arranged into a motor-cargo complex to perform the necessary work Gross, Hither and yon: a review of bidirectional microtubule-based transport (Gross in Phys. Biol. 1:R1-R11, 2004). Although these models have provided us with important insights into these phenomena, there are still many unanswered questions regarding the mechanisms through which the movement of the complex takes place on crowded microtubules. For example (i) how does cargo-binding affect motor motility? and in connection with that - (ii) how does the presence of other motors (and also other cargos) on the microtubule affect the motility of the motor-cargo complex? We discuss these questions from a different perspective. The movement of a cargo is conceived here as a hopping process resulting from the transference of cargo between neighboring motors. In the light of this, we examine the conditions under which cargo might display bidirectional movement even if directed by motors of a single polarity. The global properties of the model in the long-time regime are obtained by mapping the dynamics of the collection of interacting motors and cargos into an asymmetric simple exclusion process (ASEP) which can be resolved using the matrix ansatz introduced by Derrida (Derrida and Evans in Nonequilibrium Statistical Mechanics in One Dimension, pp. 277-304, 1997; Derrida et al. in J. Phys. A 26:1493-1517, 1993).

  20. Development of a standardized, citywide process for managing smart-pump drug libraries.

    PubMed

    Walroth, Todd A; Smallwood, Shannon; Arthur, Karen; Vance, Betsy; Washington, Alana; Staublin, Therese; Haslar, Tammy; Reddan, Jennifer G; Fuller, James

    2018-06-15

    Development and implementation of an interprofessional consensus-driven process for review and optimization of smart-pump drug libraries and dosing limits are described. The Indianapolis Coalition for Patient Safety (ICPS), which represents 6 Indianapolis-area health systems, identified an opportunity to reduce clinically insignificant alerts that smart infusion pumps present to end users. Through a consensus-driven process, ICPS aimed to identify best practices to implement at individual hospitals in order to establish specific action items for smart-pump drug library optimization. A work group of pharmacists, nurses, and industrial engineers met to evaluate variability within and lack of scrutiny of smart-pump drug libraries. The work group used Lean Six Sigma methodologies to generate a list of key needs and barriers to be addressed in process standardization. The group reviewed targets for smart-pump drug library optimization, including dosing limits, types of alerts reviewed, policies, and safety best practices. The work group also analyzed existing processes at each site to develop a final consensus statement outlining a model process for reviewing alerts and managing smart-pump data. Analysis of the total number of alerts per device across ICPS-affiliated health systems over a 4-year period indicated a 50% decrease (from 7.2 to 3.6 alerts per device per month) after implementation of the model by ICPS member organizations. Through implementation of a standardized, consensus-driven process for smart-pump drug library optimization, ICPS member health systems reduced clinically insignificant smart-pump alerts. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

  1. 43. (Credit JTL) View down into # 3 low service ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. (Credit JTL) View down into # 3 low service pump pit from elevator car. Worthington low service pump frame on left with pumps at bottom. Tunnel opening leads to #1 low service pump pit. Electric pump housing closest to tunnel opening installed in 1943; pump could deliver 6 mgd. Certrifugal pump near steps was installed in 1947 and is driven by a shaft from a motor at the top of the pit. - McNeil Street Pumping Station, McNeil Street & Cross Bayou, Shreveport, Caddo Parish, LA

  2. 46 CFR 118.300 - Fire pumps.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire pumps. 118.300 Section 118.300 Shipping COAST GUARD... OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS FIRE PROTECTION EQUIPMENT Fire Main System § 118.300 Fire pumps. (a) A self priming, power driven fire pump must be installed on each vessel. (b) On a...

  3. 46 CFR 76.10-5 - Fire pumps.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Fire pumps. 76.10-5 Section 76.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS FIRE PROTECTION EQUIPMENT Fire Main System, Details § 76.10-5 Fire pumps. (a) Vessels shall be equipped with independently driven fire pumps in...

  4. Induced charge electroosmosis micropumps using arrays of Janus micropillars.

    PubMed

    Paustian, Joel S; Pascall, Andrew J; Wilson, Neil M; Squires, Todd M

    2014-09-07

    We report on a microfluidic AC-driven electrokinetic pump that uses Induced Charge Electro-Osmosis (ICEO) to generate on-chip pressures. ICEO flows occur when a bulk electric field polarizes a metal object to induce double layer formation, then drives electroosmotic flow. A microfabricated array of metal-dielectric Janus micropillars breaks the symmetry of ICEO flow, so that an AC electric field applied across the array drives ICEO flow along the length of the pump. When pumping against an external load, a pressure gradient forms along the pump length. The design was analyzed theoretically with the reciprocal theorem. The analysis reveals a maximum pressure and flow rate that depend on the ICEO slip velocity and micropillar geometry. We then fabricate and test the pump, validating our design concept by demonstrating non-local pressure driven flow using local ICEO slip flows. We varied the voltage, frequency, and electrolyte composition, measuring pump pressures of 15-150 Pa. We use the pump to drive flows through a high-resistance microfluidic channel. We conclude by discussing optimization routes suggested by our theoretical analysis to enhance the pump pressure.

  5. Pressure charged airlift pump

    DOEpatents

    Campbell, Gene K.

    1983-01-01

    A pumping system is described for pumping fluids, such as water with entrained mud and small rocks, out of underground cavities such as drilled wells, which can effectively remove fluids down to a level very close to the bottom of the cavity and which can operate solely by compressed air pumped down through the cavity. The system utilizes a subassembly having a pair of parallel conduit sections (44, 46) adapted to be connected onto the bottom of a drill string utilized for drilling the cavity, the drill string also having a pair of coaxially extending conduits. The subassembly includes an upper portion which has means for connection onto the drill string and terminates the first conduit of the drill string in a plenum (55). A compressed air-driven pump (62) is suspended from the upper portion. The pump sucks fluids from the bottom of the cavity and discharges them into the second conduit. Compressed air pumped down through the first conduit (46) to the plenum powers the compressed air-driven pump and aerates the fluid in the second conduit to lift it to the earth's surface.

  6. Integrated regulation of motor-driven organelle transport by scaffolding proteins.

    PubMed

    Fu, Meng-meng; Holzbaur, Erika L F

    2014-10-01

    Intracellular trafficking pathways, including endocytosis, autophagy, and secretion, rely on directed organelle transport driven by the opposing microtubule motor proteins kinesin and dynein. Precise spatial and temporal targeting of vesicles and organelles requires the integrated regulation of these opposing motors, which are often bound simultaneously to the same cargo. Recent progress demonstrates that organelle-associated scaffolding proteins, including Milton/TRAKs (trafficking kinesin-binding protein), JIP1, JIP3 (JNK-interacting proteins), huntingtin, and Hook1, interact with molecular motors to coordinate activity and sustain unidirectional transport. Scaffolding proteins also bind to upstream regulatory proteins, including kinases and GTPases, to modulate transport in the cell. This integration of regulatory control with motor activity allows for cargo-specific changes in the transport or targeting of organelles in response to cues from the complex cellular environment. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Heat generation and hemolysis at the shaft seal in centrifugal blood pumps.

    PubMed

    Araki, K; Taenaka, Y; Wakisaka, Y; Masuzawa, T; Tatsumi, E; Nakatani, T; Baba, Y; Yagura, A; Eya, K; Toda, K

    1995-01-01

    The heat and hemolysis around a shaft seal were investigated. Materials were original pumps (Nikkiso HMS-15:N-original, and 3M Delphin:D-original), vane-removed pumps (Nvane(-), Dvane(-)), and a small chamber with a shaft coiled by nichrome wire (mock pump). The original pumps were driven at 500 mmHg and 5 L/min, and vane-removed pumps were driven at the same rotation number. An electrical powers of 0, 0.5, 2, and 10 W was supplied to the mock pumps. In vitro hemolytic testing showed that hemolytic indices were 0.027 g/100 L in N-original, 0.013 in Nvane(-), 0.061 in D-original, and 0.012 in Dvane(-). Measurement of heat with a thermally insulated water chamber showed total heat within the pump of 8.62 and 10.85 W, and heat at the shaft seal of 0.87 and 0.62 W in the Nikkiso and Delphin pumps, respectively. Hemolysis and heat generation of mock pumps remained low. The results indicate that the heat generated around the shaft seal was minimal. Hemolysis at the shaft-seal was considerable but not major. Local heat did not affect hemolysis. It was concluded that the shaft-seal affected hemolysis, not by local heat but friction itself.

  8. Exciton Absorption in Semiconductor Quantum Wells Driven by a Strong Intersubband Pump Field

    NASA Technical Reports Server (NTRS)

    Liu, Ansheng; Ning, Cun-Zheng

    1999-01-01

    Optical interband excitonic absorption of semiconductor quantum wells (QW's) driven by a coherent pump field is investigated based on semiconductor Bloch equations. The pump field has a photon energy close to the intersubband spacing between the first two conduction subbands in the QW's. An external weak optical field probes the interband transition. The excitonic effects and pump-induced population redistribution within the conduction subbands in the QW system are included. When the density of the electron-hole pairs in the QW structure is low, the pump field induces an Autler-Townes splitting of the exciton absorption spectrum. The split size and the peak positions of the absorption doublet depend not only on the pump frequency and intensity but also on the carrier density. As the density of the electron-hole pairs is increased, the split contrast (the ratio between the maximum and minimum values) is decreased because the exciton effect is suppressed at higher densities due to the many-body screening.

  9. Collinear swimmer propelling a cargo sphere at low Reynolds number.

    PubMed

    Felderhof, B U

    2014-11-01

    The swimming velocity and rate of dissipation of a linear chain consisting of two or three little spheres and a big sphere is studied on the basis of low Reynolds number hydrodynamics. The big sphere is treated as a passive cargo, driven by the tail of little spheres via hydrodynamic and direct elastic interaction. The fundamental solution of Stokes equations in the presence of a sphere with a no-slip boundary condition, as derived by Oseen, is used to model the hydrodynamic interactions between the big sphere and the little spheres.

  10. KSC-06pd0924

    NASA Image and Video Library

    2006-05-23

    KENNEDY SPACE CENTER, FLA. -- From inside the payload changeout room on the rotating service structure on Launch Pad 39B, the multi-purpose logistics module Leonardo is being moved into Space Shuttle Discovery's payload bay. The payload ground-handling mechanism (PGHM) is used to transfer the module into the payload bay. Leonardo is a reusable logistics carrier. It is the primary delivery system used to resupply and return station cargo requiring a pressurized environment. Leonardo is part of the payload on mission STS-121. Other payloads include the integrated cargo carrier with the mobile transporter reel assembly and a spare pump module, and the lightweight multi-purpose experiment support structure carrier. Discovery is scheduled to launch in a window extending from July 1 through July 19. Photo credit: NASA/Jack Pfaller

  11. KSC-06pd0927

    NASA Image and Video Library

    2006-05-23

    KENNEDY SPACE CENTER, FLA. -- From inside the payload changeout room on the rotating service structure on Launch Pad 39B, the multi-purpose logistics module Leonardo is lowered into Space Shuttle Discovery's payload bay. The payload ground-handling mechanism (PGHM) is used to transfer the module into the payload bay. Leonardo is a reusable logistics carrier. It is the primary delivery system used to resupply and return station cargo requiring a pressurized environment. Leonardo is part of the payload on mission STS-121. Other payloads include the integrated cargo carrier with the mobile transporter reel assembly and a spare pump module, and the lightweight multi-purpose experiment support structure carrier. Discovery is scheduled to launch in a window extending from July 1 through July 19. Photo credit: NASA/Jack Pfaller

  12. Vanadium-pumped titanium x-ray laser

    DOEpatents

    Nilsen, J.

    1992-05-26

    A resonantly photo-pumped x-ray laser is formed of a vanadium and titanium foil combination that is driven by two beams of intense line focused optical laser radiation. Ground state neon-like titanium ions are resonantly photo-pumped by line emission from fluorine-like vanadium ions. 4 figs.

  13. Peroxidase-mediated Biodegradation of Carbon Nanotubes in vitro and in vivo

    PubMed Central

    Kotchey, Gregg P.; Zhao, Yong; Kagan, Valerian E.; Star, Alexander

    2013-01-01

    As a result of their unique electronic, optical, and mechanical properties, carbon nanotubes (CNTs) have been implemented in therapeutic and imaging applications. In an idealized situation, CNTs would be disposed of after they transport their theranostic payloads. Biodegradation represents an attractive pathway for the eliminating of CNT carriers post-delivery and may be integral in catalyzing the release of the cargo from the delivery vehicle. Accordingly, recent research efforts have focused on peroxidase-driven biodegradation of CNTs. In this review, we not only summarize recent efforts to biodegrade CNTs in the test tube, in vitro, and in vivo, but also attempt to explore the fundamental parameters underlying degradation. Encouraged by the in vivo results obtained to date, we envision a future, where carbon-based nano-containers, which are specifically designed to target organs/cells, deliver their cargo, and biodegrade via peroxidase-driven mechanism, will represent an attractive therapeutic delivery option in nanomedicine. PMID:23856412

  14. Gas Fride Heat Pumps : The Present and Future

    NASA Astrophysics Data System (ADS)

    Kurosawa, Shigekichi; Ogura, Masao

    In japan techniques for saving energy is an important goal since energy resources such as oil and nuclear power are limited. Recently gas fired absorption heat pumps and gas engine driven heat pumps have been installed in facilifies such as hotels, swimming pools and offices.
    In this article recent techniques, applications and future aspects for gas fired heat pumps are explained.

  15. Fuel savings with conventional hot water space heating systems by incorporating a natural gas powered heat pump. Preliminary project: Development of heat pump technology

    NASA Astrophysics Data System (ADS)

    Vanheyden, L.; Evertz, E.

    1980-12-01

    Compression type air/water heat pumps were developed for domestic heating systems rated at 20 to 150 kW. The heat pump is driven either by a reciprocating piston or rotary piston engine modified to operate on natural gas. Particular features of natural gas engines as prime movers, such as waste heat recovery and variable speed, are stressed. Two systems suitable for heat pump operation were selected from among five different mass produced car engines and were modified to incorporate reciprocating piston compressor pairs. The refrigerants used are R 12 and R 22. Test rig data transferred to field conditions show that the fuel consumption of conventional boilers can be reduced by 50% and more by the installation of engine driven heat pumps. Pilot heat pumps based on a 1,600 cc reciprocating piston engine were built for heating four two-family houses. Pilot pump operation confirms test rig findings. The service life of rotary piston and reciprocating piston engines was investigated. The tests reveal characteristic curves for reciprocating piston engines and include exhaust composition measurements.

  16. Evaluation of Future Fuels in a High Pressure Common Rail System - Part 1 Cummins XPI

    DTIC Science & Technology

    2012-10-01

    compressed against the underside of the pump head to maintain contact with the pump camshaft. The underside of the pump head is shown in Figure 5...Figure 5. High Pressure Pump Head Unclassified 8 The two barrel retainers located on the underside of the pump head hold the ceramic plungers...which develop the high pressures within the pump. The plungers are driven into the barrels by the tappets as the shaft turns. They are forced back out

  17. 49 CFR 178.338-17 - Pumps and compressors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.338-17 Pumps and compressors. (a) Liquid pumps and gas compressors, if used, must be of suitable design, adequately protected against breakage by collision, and kept in good condition. They may be driven by motor vehicle power take...

  18. 49 CFR 178.337-15 - Pumps and compressors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PACKAGINGS Specifications for Containers for Motor Vehicle Transportation § 178.337-15 Pumps and compressors. (a) Liquid pumps or gas compressors, if used, must be of suitable design, adequately protected against breakage by collision, and kept in good condition. They may be driven by motor vehicle power take...

  19. Decontamination of Water Containing Radiological Warfare Agents

    DTIC Science & Technology

    1975-03-01

    debris was cond~ucted undcr Project Snowball. Open tanks of water were exposed to a 500- toxi TNT explosion 2 at varying distances from grouind zero...trailhr; 4-cylinder, 4-stroke, liquid- cooled gasoline engine: aluminum evaporator-conden ser; vapor complressor; watcr pumps; heat exchanger; cngine...field consists of a 10-kw gasoline -engine-driven generator and three electric-motor-driven pumps. See Figure 21 for a photograph of the cation and anion

  20. A charge-driven molecular water pump.

    PubMed

    Gong, Xiaojing; Li, Jingyuan; Lu, Hangjun; Wan, Rongzheng; Li, Jichen; Hu, Jun; Fang, Haiping

    2007-11-01

    Understanding and controlling the transport of water across nanochannels is of great importance for designing novel molecular devices, machines and sensors and has wide applications, including the desalination of seawater. Nanopumps driven by electric or magnetic fields can transport ions and magnetic quanta, but water is charge-neutral and has no magnetic moment. On the basis of molecular dynamics simulations, we propose a design for a molecular water pump. The design uses a combination of charges positioned adjacent to a nanopore and is inspired by the structure of channels in the cellular membrane that conduct water in and out of the cell (aquaporins). The remarkable pumping ability is attributed to the charge dipole-induced ordering of water confined in the nanochannels, where water can be easily driven by external fields in a concerted fashion. These findings may provide possibilities for developing water transport devices that function without osmotic pressure or a hydrostatic pressure gradient.

  1. Efficacy and safety of strategies to preserve stable extracorporeal life support flow during simulated hypovolemia.

    PubMed

    Simons, A P; Lindelauf, A A M A; Ganushchak, Y M; Maessen, J G; Weerwind, P W

    2014-01-01

    Without volume-buffering capacity in extracorporeal life support (ELS) systems, hypovolemia can acutely reduce support flow. This study aims at evaluating efficacy and safety of strategies for preserving stable ELS during hypovolemia. Flow and/or pressure-guided servo pump control, a reserve-driven control strategy and a volume buffer capacity (VBC) device were evaluated with respect to pump flow, venous line pressure and arterial gaseous microemboli (GME) during simulated normovolemia and hypovolemia. Normovolemia resulted in a GME-free pump flow of 3.1 ± 0.0 L/min and a venous line pressure of -10 ± 1 mmHg. Hypovolemia without servo pump control resulted in a GME-loaded flow of 2.3 ± 0.4 L/min with a venous line pressure of -114 ± 52 mmHg. Servo control resulted in an unstable and GME-loaded flow of 1.5 ± 1.2 L/min. With and without servo pump control, the VBC device stabilised flow (SD = 0.2 and 0.0 L/min, respectively) and venous line pressure (SD=51 and 4 mmHg, respectively) with near-absent GME activity. Reserve-driven pump control combined with a VBC device restored a near GME-free flow of 2.7 ± 0.0 L/min with a venous line pressure of -9 ± 0 mmHg. In contrast to a reserve-driven pump control strategy combined with a VBC device, flow and pressure servo control for ELS show evident deficits in preserving stable and safe ELS flow during hypovolemia.

  2. Microtubule defects influence kinesin-based transport in vitro.

    NASA Astrophysics Data System (ADS)

    Xu, Jing

    Microtubules are protein polymers that form ``molecular highways'' for long-range transport within living cells. Molecular motors actively step along microtubules to shuttle cellular materials between the nucleus and the cell periphery; this transport is critical for the survival and health of all eukaryotic cells. Structural defects in microtubules exist, but whether these defects impact molecular motor-based transport remains unknown. Here, we report a new, to our knowledge, approach that allowed us to directly investigate the impact of such defects. Using a modified optical-trapping method, we examined the group function of a major molecular motor, conventional kinesin, when transporting cargos along individual microtubules. We found that microtubule defects influence kinesin-based transport in vitro. The effects depend on motor number: cargos driven by a few motors tended to unbind prematurely from the microtubule, whereas cargos driven by more motors tended to pause. To our knowledge, our study provides the first direct link between microtubule defects and kinesin function. The effects uncovered in our study may have physiological relevance in vivo. Supported by the UC Merced (to J.X.), NIH (NS048501 to S.J.K.), NSF (EF-1038697 to A.G.), and the James S. McDonnell Foundation (to A.G.). Work carried out at the Aspen Center for Physics was supported by NSF Grant PHY-1066293.

  3. Engine having multiple pumps driven by a single shaft

    DOEpatents

    Blass, James R.

    2001-01-01

    An engine comprises an engine housing. A first engine fluid sub-system that includes a first pump and the engine housing defining a first fluid passage is also included in the engine. The engine also includes at least one additional engine fluid sub-system that includes a second pump and the engine housing defining a second fluid passage. A rotating shaft is at least partially positioned in the engine housing, the first pump and the second pump.

  4. Gyro-effect stabilizes unstable permanent maglev centrifugal pump.

    PubMed

    Qian, Kun-Xi

    2007-03-01

    According to Earnshaw's Theorem (1839), the passive maglev cannot achieve stable equilibrium and thus an extra coil is needed to make the rotor electrically levitated in a heart pump. The author had developed a permanent maglev centrifugal pump utilizing only passive magnetic bearings, to keep the advantages but to avoid the disadvantages of the electric maglev pumps. The equilibrium stability was achieved by use of so-called "gyro-effect": a rotating body with certain high speed can maintain its rotation stably. This pump consisted of a rotor (driven magnets and an impeller), and a stator with motor coil and pump housing. Two passive magnetic bearings between rotor and stator were devised to counteract the attractive force between the motor coil iron core and the rotor driven magnets. Bench testing with saline demonstrated a levitated rotor under preconditions of higher than 3,250 rpm rotation and more than 1 l/min pumping flow. Rotor levitation was demonstrated by 4 Hall sensors on the stator, with evidence of reduced maximal eccentric distance from 0.15 mm to 0.07 mm. The maximal rotor vibration amplitude was 0.06 mm in a gap of 0.15 mm between rotor and stator. It concluded that Gyro-effect can help passive maglev bearings to achieve stabilization of permanent maglev pump; and that high flow rate indicates good hydraulic property of the pump, which helps also the stability of passive maglev pump.

  5. 33 CFR 151.13 - Special areas for Annex I of MARPOL 73/78.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... are the Mediterranean Sea area, the Baltic Sea area, the Black Sea area, the Red Sea area, the Gulfs... bilge water does not originate from cargo pump room bilges; (2) The bilge water is not mixed with oil... § 151.13 for the Red Sea area, Gulfs area, Gulf of Aden area, the Oman area of the Arabian Sea, and the...

  6. 33 CFR 151.13 - Special areas for Annex I of MARPOL 73/78.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... are the Mediterranean Sea area, the Baltic Sea area, the Black Sea area, the Red Sea area, the Gulfs... bilge water does not originate from cargo pump room bilges; (2) The bilge water is not mixed with oil... § 151.13 for the Red Sea area, Gulfs area, Gulf of Aden area, the Oman area of the Arabian Sea, and the...

  7. 33 CFR 151.13 - Special areas for Annex I of MARPOL 73/78.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... are the Mediterranean Sea area, the Baltic Sea area, the Black Sea area, the Red Sea area, the Gulfs... bilge water does not originate from cargo pump room bilges; (2) The bilge water is not mixed with oil... § 151.13 for the Red Sea area, Gulfs area, Gulf of Aden area, the Oman area of the Arabian Sea, and the...

  8. Vanadium-pumped titanium x-ray laser

    DOEpatents

    Nilsen, Joseph

    1992-01-01

    A resonantly photo-pumped x-ray laser (10) is formed of a vanadium (12) and titanium (14) foil combination (16) that is driven by two beams (18, 20) of intense line focused (22, 24) optical laser radiation. Ground state neon-like titanium ions (34) are resonantly photo-pumped by line emission from fluorine-like vanadium ions (32).

  9. Investigation of lunar base thermal control system options

    NASA Technical Reports Server (NTRS)

    Ewart, Michael K.

    1993-01-01

    Long duration human exploration missions to the Moon will require active thermal control systems which have not previously been used in space. The two technologies which are most promising for long term lunar base thermal control are heat pumps and radiator shades. Recent trade-off studies at the Johnson Space Center have focused development efforts on the most promising heat pump and radiator shade technologies. Since these technologies are in the early stages of development and many parameters used in the study are not well defined, a parametric study was done to test the sensitivity to each assumption. The primary comparison factor in these studies was the total mass system, with power requirements included in the form of a mass penalty for power. Heat pump technologies considered were thermally driven heat pumps such as metal hydride, complex compound, absorption and zeolite. Also considered were electrically driven Stirling and vapor compression heat pumps. Radiator shade concepts considered included step shaped, V-shaped and parabolic (or catenary) shades and ground covers. A further trade study compared the masses of heat pump and radiator shade systems.

  10. Characterization of a membrane-based, electrochemically driven pumping system using aqueous electrolyte solutions.

    PubMed

    Norman, Mya A; Evans, Christine E; Fuoco, Anthony R; Noble, Richard D; Koval, Carl A

    2005-10-01

    Electrokinetic flow provides a mechanism for a variety of fluid pumping schemes. The design and characterization of an electrochemically driven pump that utilizes porous carbon electrodes, iodide/triiodide redox electrolytes, and Nafion membranes is described. Fluid pumping by the cell is reversible and controlled by the cell current. Chronopotentiometry experiments indicate that the total available fluid that can be pumped in a single electrolysis without gas evolution is determined solely by the initial concentration of electrolyte and the applied current. The magnitude of the fluid flow at a given current is determined by the nature of the cation in the electrolyte and by the water absorption properties of the Nafion membrane. For 1 M aqueous electrolytes, pumping rates ranging from 1 to 14 microL/min were obtained for current densities of 10-30 mA/cm2 of membrane area. Molar volume changes for the I3-/I- redox couple and for the alkali cation migration contribute little to the observed volumetric flow rates; the magnitude of the flow is dominated by the migration-induced flow of water.

  11. Geothermal energy control system and method

    DOEpatents

    Matthews, Hugh B.

    1977-01-01

    A geothermal energy transfer and utilization system makes use of thermal energy stored in hot solute-bearing well water to generate super-heated steam from an injected flow of clean water; the super-heated steam is then used for operating a turbine-driven pump at the well bottom for pumping the hot solute-bearing water at high pressure and in liquid state to the earth's surface, where it is used by transfer of its heat to a closed-loop boiler-turbine-alternator combination for the generation of electrical or other power. Residual concentrated solute-bearing water is pumped back into the earth. The clean cooled water is regenerated at the surface-located system and is returned to the deep well pumping system also for lubrication of a novel bearing arrangement supporting the turbine-driven pump system. The bearing system employs liquid lubricated thrust and radial bearings with all bearing surfaces bathed in clean water serving as a lubricant and maintained under pressure to prevent entry into the bearings of contaminated geothermal fluid, an auxiliary thrust ball bearing arrangement comes into operation when starting or stopping the pumping system.

  12. Ballistic induced pumping of hypersonic heat current in DNA nano wire

    NASA Astrophysics Data System (ADS)

    Behnia, Sohrab; Panahinia, Robabe

    2016-12-01

    Heat shuttling properties of DNA nano-wire driven by an external force against the spontaneous heat current direction in non-zero temperature bias (non averaged) have been studied. We examined the valid region of driving amplitude and frequency to have pumping state in terms of temperature bias and the system size. It was shown that DNA could act as a high efficiency thermal pump in the hypersonic region. Amplitude-dependent resonance frequencies of DNA indicating intrinsic base pair internal vibrations have been detected. Nonlinearity implies that by increasing the driven amplitude new vibration modes are detected. To verify the results, an analytical parallel investigation based on multifractal concept has been done. By using the geometric properties of the strange attractor of the system, the threshold value to transition to the pumping state for given external amplitude has been identified. It was shown that the system undergoes a phase transition in sliding point to the pumping state. Fractal dimension demonstrates that the ballistic transport is responsible for energy pumping in the system. In the forbidden band gap, DNA could transmit the energy by exceeding the threshold amplitude. Despite of success in energy pumping, in this framework, DNA could not act as a real cooler.

  13. Fuel Delivery System.

    DTIC Science & Technology

    1996-07-24

    to fuel tank 27 aboard 23 test torpedo 26. Pressure switch 19B operates to close solenoid 24 valve 22A and concurrently open solenoid valve 22D...leading to a pump explosion. The boost pump 4 is driven by its 11 motor 14B and positive displacement pump 1 by its respective 12 motor 14A. Pressure ... switch 19A monitors the head pressure 13 created by the boost pump 4 and it will shut off the motor 14A of 14 the positive displacement pump 1 if

  14. Gas-driven pump for ground-water samples

    USGS Publications Warehouse

    Signor, Donald C.

    1978-01-01

    Observation wells installed for artificial-recharge research and other wells used in different ground-water programs are frequently cased with small-diameter steel pipe. To obtain samples from these small-diameter wells in order to monitor water quality, and to calibrate solute-transport models, a small-diameter pump with unique operating characteristics is required that causes a minimum alternation of samples during field sampling. A small-diameter gas-driven pump was designed and built to obtain water samples from wells of two-inch diameter or larger. The pump is a double-piston type with the following characteristics: (1) The water sample is isolated from the operating gas, (2) no source of electricity is ncessary, (3) operation is continuous, (4) use of compressed gas is efficient, and (5) operation is reliable over extended periods of time. Principles of operation, actual operation techniques, gas-use analyses and operating experience are described. Complete working drawings and a component list are included. Recent modifications and pump construction for high-pressure applications also are described. (Woodard-USGS)

  15. Valving for controlling a fluid-driven reciprocating apparatus

    DOEpatents

    Whitehead, John C.

    1995-01-01

    A pair of control valve assemblies for alternately actuating a pair of fluid-driven free-piston devices by using fluid pressure communication therebetween. Each control valve assembly is switched by a pressure signal depending on the state of its counterpart's piston. The communication logic is arranged to provide overlap of the forward strokes of the pistons, so that at least one of the pair will always be pressurized. Thus, uninterrupted pumping of liquid is made possible from a pair of free-piston pumps. In addition, the speed and frequency of piston stroking is entirely dependent on the mechanical power load applied. In the case of a pair of pumps, this enables liquid delivery at a substantially constant pressure over the full range of flow rates, from zero to maximum flow. Each of the valve assemblies uses an intake-exhaust valve and a signal valve with the signal valve of one pump being connected to be pressure responsive to the piston of the opposite cylinder or pump.

  16. Valving for controlling a fluid-driven reciprocating apparatus

    DOEpatents

    Whitehead, J.C.

    1995-06-27

    A pair of control valve assemblies is described for alternately actuating a pair of fluid-driven free-piston devices by using fluid pressure communication therebetween. Each control valve assembly is switched by a pressure signal depending on the state of its counterpart`s piston. The communication logic is arranged to provide overlap of the forward strokes of the pistons, so that at least one of the pair will always be pressurized. Thus, uninterrupted pumping of liquid is made possible from a pair of free-piston pumps. In addition, the speed and frequency of piston stroking is entirely dependent on the mechanical power load applied. In the case of a pair of pumps, this enables liquid delivery at a substantially constant pressure over the full range of flow rates, from zero to maximum flow. Each of the valve assemblies uses an intake-exhaust valve and a signal valve with the signal valve of one pump being connected to be pressure responsive to the piston of the opposite cylinder or pump. 15 figs.

  17. KSC-06pd0926

    NASA Image and Video Library

    2006-05-23

    KENNEDY SPACE CENTER, FLA. -- From inside the payload changeout room on the rotating service structure on Launch Pad 39B, workers maneuver the multi-purpose logistics module Leonardo into Space Shuttle Discovery's payload bay (at left). The payload ground-handling mechanism (PGHM) is used to transfer the module into the payload bay. Leonardo is a reusable logistics carrier. It is the primary delivery system used to resupply and return station cargo requiring a pressurized environment. Leonardo is part of the payload on mission STS-121. Other payloads include the integrated cargo carrier with the mobile transporter reel assembly and a spare pump module, and the lightweight multi-purpose experiment support structure carrier. Discovery is scheduled to launch in a window extending from July 1 through July 19. Photo credit: NASA/Jack Pfaller

  18. KSC-06pd0925

    NASA Image and Video Library

    2006-05-23

    KENNEDY SPACE CENTER, FLA. -- From inside the payload changeout room on the rotating service structure on Launch Pad 39B, the multi-purpose logistics module Leonardo is being moved into Space Shuttle Discovery's payload bay (at left). The payload ground-handling mechanism (PGHM) is used to transfer the module into the payload bay. Leonardo is a reusable logistics carrier. It is the primary delivery system used to resupply and return station cargo requiring a pressurized environment. Leonardo is part of the payload on mission STS-121. Other payloads include the integrated cargo carrier with the mobile transporter reel assembly and a spare pump module, and the lightweight multi-purpose experiment support structure carrier. Discovery is scheduled to launch in a window extending from July 1 through July 19. Photo credit: NASA/Jack Pfaller

  19. Navigating the plant cell: intracellular transport logistics in the green kingdom

    PubMed Central

    Geitmann, Anja; Nebenführ, Andreas

    2015-01-01

    Intracellular transport in plant cells occurs on microtubular and actin arrays. Cytoplasmic streaming, the rapid motion of plant cell organelles, is mostly driven by an actin–myosin mechanism, whereas specialized functions, such as the transport of large cargo or the assembly of a new cell wall during cell division, are performed by the microtubules. Different modes of transport are used, fast and slow, to either haul cargo over long distances or ascertain high-precision targeting, respectively. Various forms of the actin-specific motor protein myosin XI exist in plant cells and might be involved in different cellular functions. PMID:26416952

  20. Bi-stability in cooperative transport by ants in the presence of obstacles

    PubMed Central

    Pinkoviezky, Itai; Feinerman, Ofer

    2018-01-01

    To cooperatively carry large food items to the nest, individual ants conform their efforts and coordinate their motion. Throughout this expedition, collective motion is driven both by internal interactions between the carrying ants and a response to newly arrived informed ants that orient the cargo towards the nest. During the transport process, the carrying group must overcome obstacles that block their path to the nest. Here, we investigate the dynamics of cooperative transport, when the motion of the ants is frustrated by a linear obstacle that obstructs the motion of the cargo. The obstacle contains a narrow opening that serves as the only available passage to the nest, and through which single ants can pass but not with the cargo. We provide an analytical model for the ant-cargo system in the constrained environment that predicts a bi-stable dynamic behavior between an oscillatory mode of motion along the obstacle and a convergent mode of motion near the opening. Using both experiments and simulations, we show how for small cargo sizes, the system exhibits spontaneous transitions between these two modes of motion due to fluctuations in the applied force on the cargo. The bi-stability provides two possible problem solving strategies for overcoming the obstacle, either by attempting to pass through the opening, or take large excursions to circumvent the obstacle. PMID:29746457

  1. Bi-stability in cooperative transport by ants in the presence of obstacles.

    PubMed

    Ron, Jonathan E; Pinkoviezky, Itai; Fonio, Ehud; Feinerman, Ofer; Gov, Nir S

    2018-05-01

    To cooperatively carry large food items to the nest, individual ants conform their efforts and coordinate their motion. Throughout this expedition, collective motion is driven both by internal interactions between the carrying ants and a response to newly arrived informed ants that orient the cargo towards the nest. During the transport process, the carrying group must overcome obstacles that block their path to the nest. Here, we investigate the dynamics of cooperative transport, when the motion of the ants is frustrated by a linear obstacle that obstructs the motion of the cargo. The obstacle contains a narrow opening that serves as the only available passage to the nest, and through which single ants can pass but not with the cargo. We provide an analytical model for the ant-cargo system in the constrained environment that predicts a bi-stable dynamic behavior between an oscillatory mode of motion along the obstacle and a convergent mode of motion near the opening. Using both experiments and simulations, we show how for small cargo sizes, the system exhibits spontaneous transitions between these two modes of motion due to fluctuations in the applied force on the cargo. The bi-stability provides two possible problem solving strategies for overcoming the obstacle, either by attempting to pass through the opening, or take large excursions to circumvent the obstacle.

  2. 46 CFR 34.10-5 - Fire pumps-T/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Fire pumps-T/ALL. 34.10-5 Section 34.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS FIREFIGHTING EQUIPMENT Fire Main System, Details § 34.10-5 Fire pumps—T/ALL. (a) Tankships shall be equipped with independently driven fire pumps in...

  3. 46 CFR 34.10-5 - Fire pumps-T/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Fire pumps-T/ALL. 34.10-5 Section 34.10-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS FIREFIGHTING EQUIPMENT Fire Main System, Details § 34.10-5 Fire pumps—T/ALL. (a) Tankships shall be equipped with independently driven fire pumps in...

  4. Constant-Pressure Hydraulic Pump

    NASA Technical Reports Server (NTRS)

    Galloway, C. W.

    1982-01-01

    Constant output pressure in gas-driven hydraulic pump would be assured in new design for gas-to-hydraulic power converter. With a force-multiplying ring attached to gas piston, expanding gas would apply constant force on hydraulic piston even though gas pressure drops. As a result, pressure of hydraulic fluid remains steady, and power output of the pump does not vary.

  5. 46 CFR 28.820 - Fire pumps, fire mains, fire hydrants, and fire hoses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Fire pumps, fire mains, fire hydrants, and fire hoses... REQUIREMENTS FOR COMMERCIAL FISHING INDUSTRY VESSELS Aleutian Trade Act Vessels § 28.820 Fire pumps, fire mains, fire hydrants, and fire hoses. (a) Each vessel must be equipped with a self-priming, power driven fire...

  6. Thermally driven microfluidic pumping via reversible shape memory polymers

    NASA Astrophysics Data System (ADS)

    Robertson, J. M.; Rodriguez, R. X.; Holmes, L. R., Jr.; Mather, P. T.; Wetzel, E. D.

    2016-08-01

    The need exists for autonomous microfluidic pumping systems that utilize environmental cues to transport fluid within a network of channels for such purposes as heat distribution, self-healing, or optical reconfiguration. Here, we report on reversible thermally driven microfluidic pumping enabled by two-way shape memory polymers. After developing a suitable shape memory polymer (SMP) through variation in the crosslink density, thin and flexible microfluidic devices were constructed by lamination of plastic films with channels defined by laser-cutting of double-sided adhesive film. SMP blisters integrated into the devices provide thermally driven pumping, while opposing elastic blisters are used to generate backpressure for reversible operation. Thermal cycling of the device was found to drive reversible fluid flow: upon heating to 60 °C, the SMP rapidly contracted to fill the surface channels with a transparent fluid, and upon cooling to 8 °C the flow reversed and the channel re-filled with black ink. Combined with a metallized backing layer, this device results in refection of incident light at high temperatures and absorption of light (at the portions covered with channels) at low temperatures. We discuss power-free, autonomous applications ranging from thermal regulation of structures to thermal indication via color change.

  7. Enhanced Component Performance Study: Motor-Driven Pumps 1998–2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schroeder, John Alton

    2016-02-01

    This report presents an enhanced performance evaluation of motor-driven pumps at U.S. commercial nuclear power plants. The data used in this study are based on the operating experience failure reports from fiscal year 1998 through 2014 for the component reliability as reported in the Institute of Nuclear Power Operations (INPO) Consolidated Events Database (ICES). The motor-driven pump failure modes considered for standby systems are failure to start, failure to run less than or equal to one hour, and failure to run more than one hour; for normally running systems, the failure modes considered are failure to start and failure tomore » run. An eight hour unreliability estimate is also calculated and trended. The component reliability estimates and the reliability data are trended for the most recent 10-year period while yearly estimates for reliability are provided for the entire active period. Statistically significant increasing trends were identified in pump run hours per reactor year. Statistically significant decreasing trends were identified for standby systems industry-wide frequency of start demands, and run hours per reactor year for runs of less than or equal to one hour.« less

  8. Project LOCOST: Laser or Chemical Hybrid Orbital Space Transport

    NASA Technical Reports Server (NTRS)

    Dixon, Alan; Kost, Alicia; Lampshire, Gregory; Larsen, Rob; Monahan, Bob; Wright, Geoff

    1990-01-01

    A potential mission in the late 1990s is the servicing of spacecraft assets located in GEO. The Geosynchronous Operations Support Center (GeoShack) will be supported by a space transfer vehicle based at the Space Station (SS). The vehicle will transport cargo between the SS and the GeoShack. A proposed unmanned, laser or chemical hybrid orbital space transfer vehicle (LOCOST) can be used to efficiently transfer cargo between the two orbits. A preliminary design shows that an unmanned, laser/chemical hybrid vehicle results in the fuel savings needed while still providing fast trip times. The LOCOST vehicle receives a 12 MW laser beam from one Earth orbiting, solar pumped, iodide Laser Power Station (LPS). Two Energy Relay Units (ERU) provide laser beam support during periods of line-of-sight blockage by the Earth. The baseline mission specifies a 13 day round trip transfer time. The ship's configuration consist of an optical train, one hydrogen laser engine, two chemical engines, a 18 m by 29 m box truss, a mission-flexible payload module, and propellant tanks. Overall vehicle dry mass is 8,000 kg. Outbound cargo mass is 20,000 kg, and inbound cargo mass is 6,000 kg. The baseline mission needs 93,000 kg of propellants to complete the scenario. Fully fueled, outbound mission mass is 121,000 kg. A regeneratively cooled, single plasma, laser engine design producing a maximum of 768 N of thrust is utilized along with two traditional chemical engines. The payload module is designed to hold 40,000 kg of cargo, though the baseline mission specifies less. A proposed design of a laser/chemical hybrid vehicle provides a trip time and propellant efficient means to transport cargo from the SS to a GeoShack. Its unique, hybrid propulsion system provides safety through redundancy, allows baseline missions to be efficiently executed, while still allowing for the possibility of larger cargo transfers.

  9. Fossum during EVA 1

    NASA Image and Video Library

    2011-07-12

    S135-E-007656 (12 July 2011) --- NASA astronaut Mike Fossum, Expedition 28 flight engineer, waits at an International Space Station's pressurized mating adapter (PMA-2) docked to the space shuttle Atlantis, as the station's robotic system moves the failed pump module (out of frame) over to the spacewalking astronaut and the shuttle's cargo bay. Fossum and crewmate Ron Garan sent six hours and 31 minutes on their July 12 spacewalk. Photo credit: NASA

  10. Pumping approximately integrable systems

    PubMed Central

    Lange, Florian; Lenarčič, Zala; Rosch, Achim

    2017-01-01

    Weak perturbations can drive an interacting many-particle system far from its initial equilibrium state if one is able to pump into degrees of freedom approximately protected by conservation laws. This concept has for example been used to realize Bose–Einstein condensates of photons, magnons and excitons. Integrable quantum systems, like the one-dimensional Heisenberg model, are characterized by an infinite set of conservation laws. Here, we develop a theory of weakly driven integrable systems and show that pumping can induce large spin or heat currents even in the presence of integrability breaking perturbations, since it activates local and quasi-local approximate conserved quantities. The resulting steady state is qualitatively captured by a truncated generalized Gibbs ensemble with Lagrange parameters that depend on the structure but not on the overall amplitude of perturbations nor the initial state. We suggest to use spin-chain materials driven by terahertz radiation to realize integrability-based spin and heat pumps. PMID:28598444

  11. Deletion of a unique loop in the mycobacterial F-ATP synthase γ subunit sheds light on its inhibitory role in ATP hydrolysis-driven H(+) pumping.

    PubMed

    Hotra, Adam; Suter, Manuel; Biuković, Goran; Ragunathan, Priya; Kundu, Subhashri; Dick, Thomas; Grüber, Gerhard

    2016-05-01

    The F1 FO -ATP synthase is one of the enzymes that is essential to meet the energy requirement of both the proliferating aerobic and hypoxic dormant stages of the life cycle of mycobacteria. Most F-ATP synthases consume ATP in the α3 :β3 headpiece to drive the γ subunit, which couples ATP cleavage with proton pumping in the c ring of FO via the bottom of the γ subunit. ATPase-driven H(+) pumping is latent in mycobacteria. The presence of a unique 14 amino acid residue loop of the mycobacterial γ subunit has been described and aligned in close vicinity to the c-ring loop Priya R et al. (2013) J Bioenerg Biomembr 45, 121-129 Here, we used inverted membrane vesicles (IMVs) of fast-growing Mycobacterium smegmatis and a variety of covalent and non-covalent inhibitors to characterize the ATP hydrolysis activity of the F-ATP synthase inside IMVs. These vesicles formed a platform to investigate the function of the unique mycobaterial γ loop by deleting the respective loop-encoding sequence (γ166-179 ) in the genome of M. smegmatis. ATP hydrolysis-driven H(+) pumping was observed in IMVs containing the Δγ166-179 mutant protein but not for IMVs containing the wild-type F-ATP synthase. In addition, when compared to the wild-type enzyme, IMVs containing the Δγ166-179 mutant protein showed increased ATP cleavage and lower levels of ATP synthesis, demonstrating that the loop affects ATPase activity, ATPase-driven H(+) pumping and ATP synthesis. These results further indicate that the loop may affect coupling of ATP hydrolysis and synthesis in a different mode. © 2016 Federation of European Biochemical Societies.

  12. Cargo-Positioning System for Next-Generation Spacecraft

    NASA Technical Reports Server (NTRS)

    Holladay, Jon; Colton, Jonathan

    2006-01-01

    A report discusses a proposed system for mounting loaded pallets in the cargo bay of a next-generation space-shuttle-like spacecraft, such that the center of mass of the cargo would lie within a 1-in. (2.54-cm) cube that would also contain the center of mass of the spacecraft. The system would include (1) an algorithm for planning the locations of the pallets, given the geometric and weight properties of the pallets, and the geometric restrictions of the cargo bay; (2) quick-connect/quick-disconnect mounting mechanisms similar to those now used on air hoses; (3) other mounting mechanisms, comprising mostly spring-loaded pins, in a locking subsystem that would prevent shifting of the pallets under load; and (4) mechanisms for performing fine position adjustments to satisfy the center-of-mass requirement. The position- adjusting mechanisms would be motor-driven lead-screw mechanisms in groups of three - one for positioning each pin of the locking subsystem along each of three mutually perpendicular coordinate axes. The system also would include a triple-threaded screw that would provide compensation for thermal expansion or contraction of the spacecraft.

  13. Laser power transmission

    NASA Technical Reports Server (NTRS)

    Conway, Edmund J.

    1992-01-01

    An overview of previous studies related to laser power transmission is presented. Particular attention is given to the use of solar pumped lasers for space power applications. Three general laser mechanisms are addressed: photodissociation lasing driven by sunlight, photoexcitation lasing driven directly by sunlight, and photoexcitation lasing driven by thermal radiation.

  14. Custom Unit Pump Development for the EVA PLSS

    NASA Technical Reports Server (NTRS)

    Schuller, Michael; Kurwitz, Cable; Little, Frank; Oinuma, Ryoji; Larsen, Ben; Goldman, Jeff; Reinis, Filip; Trevino, Luis

    2010-01-01

    This paper describes the effort by the Texas Engineering Experiment Station (TEES) and Honeywell for NASA to design and test a pre-flight prototype pump for use in the Extra-vehicular activity (EVA) portable life support subsystem (PLSS). Major design decisions were driven by the need to reduce the pump s mass, power, and volume compared to the existing PLSS pump. In addition, the pump must accommodate a much wider range of abnormal conditions than the existing pump, including vapor/gas bubbles and increased pressure drop when employed to cool two suits simultaneously. A positive displacement, external gear type pump was selected because it offers the most compact and highest efficiency solution over the required range of flow rates and pressure drops. An additional benefit of selecting a gear pump design is that it is self priming and capable of ingesting non-condensable gas without becoming air locked. The chosen pump design consists of a 28 V DC, brushless, seal-less, permanent magnet motor driven, external gear pump that utilizes a Honeywell development that eliminates the need for magnetic coupling. The pump design was based on existing Honeywell designs, but incorporated features specifically for the PLSS application, including all of the key features of the flight pump. Testing at TEES verified that the pump meets the design requirements for range of flow rates, pressure drop, power consumption, working fluid temperature, operating time, gas ingestion, and restart capability under both ambient and vacuum conditions. The pump operated at 40 to 240 lbm/hr flow rate, 35 to 100 oF pump temperature, and 5 to 10 psid pressure rise. Power consumption of the pump controller at the nominal operating point in both ambient and vacuum conditions was 9.5 W, which was less than the 12 W predicted. Gas ingestion capabilities were tested by injecting 100 cc of air into the fluid line; the pump operated normally throughout this test.

  15. Active and passive transport of cargo in a corrugated channel: A lattice model study

    NASA Astrophysics Data System (ADS)

    Dey, Supravat; Ching, Kevin; Das, Moumita

    2018-04-01

    Inside cells, cargos such as vesicles and organelles are transported by molecular motors to their correct locations via active motion on cytoskeletal tracks and passive, Brownian diffusion. During the transportation of cargos, motor-cargo complexes (MCCs) navigate the confining and crowded environment of the cytoskeletal network and other macromolecules. Motivated by this, we study a minimal two-state model of motor-driven cargo transport in confinement and predict transport properties that can be tested in experiments. We assume that the motion of the MCC is directly affected by the entropic barrier due to confinement if it is in the passive, unbound state but not in the active, bound state where it moves with a constant bound velocity. We construct a lattice model based on a Fokker Planck description of the two-state system, study it using a kinetic Monte Carlo method and compare our numerical results with analytical expressions for a mean field limit. We find that the effect of confinement strongly depends on the bound velocity and the binding kinetics of the MCC. Confinement effectively reduces the effective diffusivity and average velocity, except when it results in an enhanced average binding rate and thereby leads to a larger average velocity than when unconfined.

  16. Fluid-driven reciprocating apparatus and valving for controlling same

    DOEpatents

    Whitehead, John C.; Toews, Hans G.

    1993-01-01

    A control valve assembly for alternately actuating a pair of fluid-driven free-piston devices by using fluid pressure communication therebetween. Each control valve is switched by a pressure signal depending on the state of its counterpart's piston. The communication logic is arranged to provide overlap of the forward strokes of the pistons, so that at least one of the pair will always be pressurized. Thus, uninterrupted pumping of liquid is made possible from a pair of free-piston pumps. In addition, the speed and frequency of piston stroking is entirely dependent on the mechanical power load applied. In the case of a pair of pumps, this enables liquid delivery at a substantially constant pressure over the full range of flow rates, from zero to maximum flow. One embodiment of the invention utilized two pairs of fluid-driven free-piston devices whereby a bipropellant liquid propulsion system may be operated, so as to provide continuous flow of both fuel and oxidizer liquids when used in rocket applications, for example.

  17. Flow pumping system for physiological waveforms.

    PubMed

    Tsai, William; Savaş, Omer

    2010-02-01

    A pulsatile flow pumping system is developed to replicate flow waveforms with reasonable accuracy for experiments simulating physiological blood flows at numerous points in the body. The system divides the task of flow waveform generation between two pumps: a gear pump generates the mean component and a piston pump generates the oscillatory component. The system is driven by two programmable servo controllers. The frequency response of the system is used to characterize its operation. The system has been successfully tested in vascular flow experiments where sinusoidal, carotid, and coronary flow waveforms are replicated.

  18. New concepts and new design of permanent maglev rotary artificial heart blood pumps.

    PubMed

    Qian, K X; Zeng, P; Ru, W M; Yuan, H Y

    2006-05-01

    According to tradition, permanent maglev cannot achieve stable equilibrium. The authors have developed, to the contrary, two stable permanent maglev impeller blood pumps. The first pump is an axially driven uni-ventricular assist pump, in which the rotor with impeller is radially supported by two passive magnetic bearings, but has one point contact with the stator axially at standstill. As the pump raises its rotating speed, the increasing hydrodynamic force of fluid acting on the impeller will make the rotor taking off from contacting point and disaffiliate from the stator. Then the rotor becomes fully suspended. The second pump is a radially driven bi-ventricular assist pump, i.e., an impeller total artificial heart. Its rotor with two impellers on both ends is supported by two passive magnetic bearings, which counteract the attractive force between rotor magnets and stator coil iron core. The rotor is affiliated to the stator radially at standstill and becomes levitated during rotation. Therefore, the rotor keeps concentric with stator during rotation but eccentric at standstill, as is confirmed by rotor position detection with Honeywell sensors. It concludes that the permanent maglev needs action of a non-magnetic force to achieve stability but a rotating magnetic levitator with high speed and large inertia can maintain its stability merely with passive magnetic bearings.

  19. Observation of the Rabi oscillation of light driven by an atomic spin wave.

    PubMed

    Chen, L Q; Zhang, Guo-Wan; Bian, Cheng-Ling; Yuan, Chun-Hua; Ou, Z Y; Zhang, Weiping

    2010-09-24

    Coherent conversion between a Raman pump field and its Stokes field is observed in a Raman process with a strong atomic spin wave initially prepared by another Raman process operated in the stimulated emission regime. The oscillatory behavior resembles the Rabi oscillation in atomic population in a two-level atomic system driven by a strong light field. The Rabi-like oscillation frequency is found to be related to the strength of the prebuilt atomic spin wave. High conversion efficiency of 40% from the Raman pump field to the Stokes field is recorded and it is independent of the input Raman pump field. This process can act as a photon frequency multiplexer and may find wide applications in quantum information science.

  20. Magnetic Heat Pump Containing Flow Diverters

    NASA Technical Reports Server (NTRS)

    Howard, Frank S.

    1995-01-01

    Proposed magnetic heat pump contains flow diverters for suppression of undesired flows. If left unchecked, undesired flows mix substantial amounts of partially heated and partially cooled portions of working fluid, effectively causing leakage of heat from heated side to cooled side. By reducing leakage of heat, flow diverters increase energy efficiency of magnetic heat pump, potentially offering efficiency greater than compressor-driven refrigerator.

  1. [Research on the feasibility of a magnetic-coupling-driven axial flow blood pump].

    PubMed

    Yu, Xiaoqing; Ding, Wenxiang; Wang, Wei; Chen, En; Jiang, Zuming; Zou, Wenyan

    2004-02-01

    A new-designed axial flow blood pump, dived by magnetic coupling and using internal hollow brushless DC motor and inlet and outlet in line with impeller, was tested in mimic circuit. The results showed good performance of the new pump and indicated that its hydrodynamic characteristic can meet the demands of clinical extracorporeal circulation and auxiliary circulation.

  2. Water Pump Development for the EVA PLSS

    NASA Technical Reports Server (NTRS)

    Schuller, Michael; Kurwitz, Cable; Goldman, Jeff; Morris, Kim; Trevino, Luis

    2009-01-01

    This paper describes the effort by the Texas Engineering Experiment Station (TEES) and Honeywell for NASA to design, fabricate, and test a preflight prototype pump for use in the Extravehicular activity (EVA) portable life support subsystem (PLSS). Major design decisions were driven by the need to reduce the pump s mass, power, and volume compared to the existing PLSS pump. In addition, the pump will accommodate a much wider range of abnormal conditions than the existing pump, including vapor/gas bubbles and increased pressure drop when employed to cool two suits simultaneously. A positive displacement, external gear type pump was selected because it offers the most compact and highest efficiency solution over the required range of flow rates and pressure drops. An additional benefit of selecting a gear pump design is that it is self priming and capable of ingesting noncondensable gas without becoming "air locked." The chosen pump design consists of a 28 V DC, brushless, sealless, permanent magnet motor driven, external gear pump that utilizes a Honeywell development that eliminates the need for magnetic coupling. Although the planned flight unit will use a sensorless motor with custom designed controller, the preflight prototype to be provided for this project incorporates Hall effect sensors, allowing an interface with a readily available commercial motor controller. This design approach reduced the cost of this project and gives NASA more flexibility in future PLSS laboratory testing. The pump design was based on existing Honeywell designs, but incorporated features specifically for the PLSS application, including all of the key features of the flight pump. Testing at TEES will simulate the vacuum environment in which the flight pump will operate. Testing will verify that the pump meets design requirements for range of flow rates, pressure rise, power consumption, working fluid temperature, operating time, and restart capability. Pump testing is currently scheduled for March, 2009, after which the pump will be delivered to NASA for further testing.

  3. FMR-driven spin pumping in Y3Fe5O12-based structures

    NASA Astrophysics Data System (ADS)

    Yang, Fengyuan; Hammel, P. Chris

    2018-06-01

    Ferromagnetic resonance driven spin pumping, a topic of steadily increasing interest since its emergence over two decades ago, remains one of the most exciting research fields in condensed matter physics. Among the many materials that have been explored for spin pumping, yttrium iron garnet (YIG) is one of the most extensively studied because of its exceptionally low magnetic damping and insulating nature. There is a great amount of literature in the spin pumping and related research fields, too broad for this review to cover. In this Topical Review, we focus on the YIG-based spin pumping results carried out by our groups, including: the mechanism and technical details of our off-axis sputtering technique for the growth of single-crystalline YIG epitaxial films with a high degree ordering, experimental evidence for the high quality of the YIG films, spin pumping results from YIG into various transition metals and their heterostructures, dynamic spin transport in YIG/antiferromagnet hybrid structures, intralayer spin pumping by localized spin wave modes confined by a micromagnetic probe, dynamic spin coupling between YIG and nitrogen-vacancy centers in diamond, parametric spin pumping from high-wavevector spin waves in YIG, and localized spin wave mode behavior in broadly tunable spatially complex magnetic configurations. These results build on the power and versatility of YIG spin pumping to improve our understanding of spin dynamics, spin currents, spin Hall physics, spin–orbit coupling, dynamic magnetic coupling, and the relationship between these phenomena in a broad range of materials, geometries, and settings.

  4. Transport Properties of Melanosomes along Microtubules Interpreted by a Tug-of-War Model with Loose Mechanical Coupling

    PubMed Central

    Bouzat, Sebastián; Levi, Valeria; Bruno, Luciana

    2012-01-01

    In this work, we explored theoretically the transport of organelles driven along microtubules by molecular motors of opposed polarities using a stochastic model that considers a Langevin dynamics for the cargo, independent cargo-motor linkers and stepping motion for the motors. It has been recently proposed that the stiffness of the motor plays an important role when multiple motors collectively transport a cargo. Therefore, we considered in our model the recently reported values for the stiffness of the cargo-motor linker determined in living cells (∼0.01 pN/nm, [1]) which is significantly lower than the motor stiffness obtained in in vitro assays and used in previous studies. Our model could reproduce the multimodal velocity distributions and typical trajectory characteristics including the properties of the reversions in the overall direction of motion observed during melanosome transport along microtubules in Xenopus laevis melanophores. Moreover, we explored the contribution of the different motility states of the cargo-motor system to the different modes of the velocity distributions and could identify the microscopic mechanisms of transport leading to trajectories compatible with those observed in living cells. Finally, by changing the attachment and detachment rates, the model could reproduce the different velocity distributions observed during melanosome transport along microtubules in Xenopus laevis melanophores stimulated for aggregation and dispersion. Our analysis suggests that active tug-of-war processes with loose mechanical coupling can account for several aspects of cargo transport along microtubules in living cells. PMID:22952716

  5. Performance Analysis of a Wind Turbine Driven Swash Plate Pump for Large Scale Offshore Applications

    NASA Astrophysics Data System (ADS)

    Buhagiar, D.; Sant, T.

    2014-12-01

    This paper deals with the performance modelling and analysis of offshore wind turbine-driven hydraulic pumps. The concept consists of an open loop hydraulic system with the rotor main shaft directly coupled to a swash plate pump to supply pressurised sea water. A mathematical model is derived to cater for the steady state behaviour of entire system. A simplified model for the pump is implemented together with different control scheme options for regulating the rotor shaft power. A new control scheme is investigated, based on the combined use of hydraulic pressure and pitch control. Using a steady-state analysis, the study shows how the adoption of alternative control schemes in a the wind turbine-hydraulic pump system may result in higher energy yields than those from a conventional system with an electrical generator and standard pitch control for power regulation. This is in particular the case with the new control scheme investigated in this study that is based on the combined use of pressure and rotor blade pitch control.

  6. Automotive and Construction Equipment for Arctic Use: Heating and Cold Starting

    DTIC Science & Technology

    1991-04-01

    heater. Catalytic combustion heaters similar to that shown in Figure 12 produce flameless heat using gasoline, benzene or a similar fuel and have... combustion chamber; physical scientist, is a • engine compartment air; and member of CRREL’s * personnel and cargo compartments. Applied Research Wind...component warping and thermal cracking. When coolant is pumped, heat is not only provided to the cylinders, thereby warming the combustion cha iber and the

  7. Jet pump assisted artery

    NASA Technical Reports Server (NTRS)

    1975-01-01

    A procedure for priming an arterial heat pump is reported; the procedure also has a means for maintaining the pump in a primed state. This concept utilizes a capillary driven jet pump to create the necessary suction to fill the artery. Basically, the jet pump consists of a venturi or nozzle-diffuser type constriction in the vapor passage. The throat of this venturi is connected to the artery. Thus vapor, gas, liquid, or a combination of the above is pumped continuously out of the artery. As a result, the artery is always filled with liquid and an adequate supply of working fluid is provided to the evaporator of the heat pipe.

  8. 29. At 1050 Gallery, Block 12, two centrifugal pumps, Buffalo ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. At 1050 Gallery, Block 12, two centrifugal pumps, Buffalo Pumps, Buffalo, NY, driven by Allis Chalmers motors (size 3 HSO, head 230, 120 cpm, 1750, rpm, Impulse dia. 15) installed in the 1960s and used for water-cooling system for 230-kv cable; the cables have been removed and the pumps are not currently used. - Columbia Basin Project, Grand Coulee Dam & Franklin D. Roosevelt Lake, Across Columbia River, Southeast of Town of Grand Coulee, Grand Coulee, Grant County, WA

  9. 46 CFR 27.301 - What are the requirements for fire pumps, fire mains, and fire hoses on towing vessels?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... must provide for your towing vessel either a self-priming, power-driven, fixed fire-pump, a fire main... fire hydrants with attached hose to reach any part of the machinery space using a single length of fire... providing a solid stream and a spray pattern. (e) The portable fire pump must be self-priming and power...

  10. 46 CFR 27.301 - What are the requirements for fire pumps, fire mains, and fire hoses on towing vessels?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... must provide for your towing vessel either a self-priming, power-driven, fixed fire-pump, a fire main... fire hydrants with attached hose to reach any part of the machinery space using a single length of fire... providing a solid stream and a spray pattern. (e) The portable fire pump must be self-priming and power...

  11. Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity.

    PubMed

    Hsu, Min-Feng; Fu, Hsu-Yuan; Cai, Chun-Jie; Yi, Hsiu-Pin; Yang, Chii-Shen; Wang, Andrew H-J

    2015-12-04

    Retinal bound light-driven proton pumps are widespread in eukaryotic and prokaryotic organisms. Among these pumps, bacteriorhodopsin (BR) proteins cooperate with ATP synthase to convert captured solar energy into a biologically consumable form, ATP. In an acidic environment or when pumped-out protons accumulate in the extracellular region, the maximum absorbance of BR proteins shifts markedly to the longer wavelengths. These conditions affect the light-driven proton pumping functional exertion as well. In this study, wild-type crystal structure of a BR with optical stability under wide pH range from a square halophilic archaeon, Haloquadratum walsbyi (HwBR), was solved in two crystal forms. One crystal form, refined to 1.85 Å resolution, contains a trimer in the asymmetric unit, whereas another contains an antiparallel dimer was refined at 2.58 Å. HwBR could not be classified into any existing subgroup of archaeal BR proteins based on the protein sequence phylogenetic tree, and it showed unique absorption spectral stability when exposed to low pH values. All structures showed a unique hydrogen-bonding network between Arg(82) and Thr(201), linking the BC and FG loops to shield the retinal-binding pocket in the interior from the extracellular environment. This result was supported by R82E mutation that attenuated the optical stability. The negatively charged cytoplasmic side and the Arg(82)-Thr(201) hydrogen bond may play an important role in the proton translocation trend in HwBR under acidic conditions. Our findings have unveiled a strategy adopted by BR proteins to solidify their defenses against unfavorable environments and maintain their optical properties associated with proton pumping. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  12. Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity*

    PubMed Central

    Hsu, Min-Feng; Fu, Hsu-Yuan; Cai, Chun-Jie; Yi, Hsiu-Pin; Yang, Chii-Shen; Wang, Andrew H.-J.

    2015-01-01

    Retinal bound light-driven proton pumps are widespread in eukaryotic and prokaryotic organisms. Among these pumps, bacteriorhodopsin (BR) proteins cooperate with ATP synthase to convert captured solar energy into a biologically consumable form, ATP. In an acidic environment or when pumped-out protons accumulate in the extracellular region, the maximum absorbance of BR proteins shifts markedly to the longer wavelengths. These conditions affect the light-driven proton pumping functional exertion as well. In this study, wild-type crystal structure of a BR with optical stability under wide pH range from a square halophilic archaeon, Haloquadratum walsbyi (HwBR), was solved in two crystal forms. One crystal form, refined to 1.85 Å resolution, contains a trimer in the asymmetric unit, whereas another contains an antiparallel dimer was refined at 2.58 Å. HwBR could not be classified into any existing subgroup of archaeal BR proteins based on the protein sequence phylogenetic tree, and it showed unique absorption spectral stability when exposed to low pH values. All structures showed a unique hydrogen-bonding network between Arg82 and Thr201, linking the BC and FG loops to shield the retinal-binding pocket in the interior from the extracellular environment. This result was supported by R82E mutation that attenuated the optical stability. The negatively charged cytoplasmic side and the Arg82–Thr201 hydrogen bond may play an important role in the proton translocation trend in HwBR under acidic conditions. Our findings have unveiled a strategy adopted by BR proteins to solidify their defenses against unfavorable environments and maintain their optical properties associated with proton pumping. PMID:26483542

  13. Phased Retrofits in Existing Homes in Florida Phase II: Shallow Plus Retrofits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sutherland, K.; Parker, D.; Martin, E.

    Originally published in February 2016, this revision contains an added section called 'Evaluation of Complete Central System Replacement with Inverter-Driven Heat Pump,' which presents the designs and energy savings evaluations of two different schemes wherein inverter-driven systems replaced a home's existing central system. Analyses for three additional retrofit measures were bolstered by longer-term data; these are described in the sections on supplemental mini-split heat pumps (MSHPs), smart thermostats, and heat pump clothes dryers. The sections on supplemental MSHPs and smart thermostats were also enhanced with larger sample sizes and projections of weather-normalized annual energy savings. Finally, peak system hour energymore » demand-reduction predictions are provided for all retrofit measures where meaningful impacts could be drawn.« less

  14. Phased Retrofits in Existing Homes in Florida Phase II: Shallow Plus Retrofits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sutherland, K.; Parker, D.; Martin, E.

    Originally published in February 2016, this revision contains an added section called 'Evaluation of Complete Central System Replacement with Inverter-Driven Heat Pump,' which presents the designs and energy savings evaluations of two different schemes wherein inverter-driven systems replaced a home’s existing central system. Analyses for three additional retrofit measures were bolstered by longer-term data; these are described in the sections on supplemental mini-split heat pumps (MSHPs), smart thermostats, and heat pump clothes dryers. The sections on supplemental MSHPs and smart thermostats were also enhanced with larger sample sizes and projections of weather-normalized annual energy savings. Finally, peak system hour energymore » demand-reduction predictions are provided for all retrofit measures where meaningful impacts could be drawn.« less

  15. M/V Elias explosion and fire at Fort Mifflin, Pa. , on 9 April 1974 with loss of life. Marine casualty report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1977-09-09

    At approximately 10 P.M. on 9 April 1974 while the M/V ELIAS was in the process of completing the discharge of a full cargo of Bachaquero crude oil at the Atlantic Richfield Oil (ARCO) Terminal, Fort Mifflin, Pennsylvania on the Delaware River the vessel sustained a series of three massive explosions, burned and sank. Nine members of the crew and four visitors (relatives of the master) perished or are missing. The M/V ELIAS was a total loss and the SS EDWARD L. STEINGER and the ARCO Terminal sustained extensive damages. The report contains the U.S. Coast Guard Marine Board ofmore » Investigation report and the Action taken by the Commandant to determine the probable cause of the casualty and the recommendations to prevent recurrence. The Commandant concurred with the Marine Board that source, and location of the initial explosion cannot be determined. Evidence of internal explosion in the after pump room, the cofferdam in the number 3 starboard cargo tanks, and in several of the cargo tanks indicate a varied path of the explosions.« less

  16. The Contribution of Compressional Magnetic Pumping to the Energization of the Earth's Outer Electron Radiation Belt During High-Speed Stream-Driven Storms

    NASA Astrophysics Data System (ADS)

    Borovsky, Joseph E.; Horne, Richard B.; Meredith, Nigel P.

    2017-12-01

    Compressional magnetic pumping is an interaction between cyclic magnetic compressions and pitch angle scattering with the scattering acting as a catalyst to allow the cyclic compressions to energize particles. Compressional magnetic pumping of the outer electron radiation belt at geosynchronous orbit in the dayside magnetosphere is analyzed by means of computer simulations, wherein solar wind compressions of the dayside magnetosphere energize electrons with electron pitch angle scattering by chorus waves and by electromagnetic ion cyclotron (EMIC) waves. The magnetic pumping is found to produce a weak bulk heating of the electron radiation belt, and it also produces an energetic tail on the electron energy distribution. The amount of energization depends on the robustness of the solar wind compressions and on the amplitude of the chorus and/or EMIC waves. Chorus-catalyzed pumping is better at energizing medium-energy (50-200 keV) electrons than it is at energizing higher-energy electrons; at high energies (500 keV-2 MeV) EMIC-catalyzed pumping is a stronger energizer. The magnetic pumping simulation results are compared with energy diffusion calculations for chorus waves in the dayside magnetosphere; in general, compressional magnetic pumping is found to be weaker at accelerating electrons than is chorus-driven energy diffusion. In circumstances when solar wind compressions are robust and when EMIC waves are present in the dayside magnetosphere without the presence of chorus, EMIC-catalyzed magnetic pumping could be the dominant energization mechanism in the dayside magnetosphere, but at such times loss cone losses will be strong.

  17. Development of a Centrifugal Pump with Improved Antithrombogenicity and Hemolytic Property for Chronic Circulatory Support.

    PubMed

    Taenaka, Yoshiyuki; Wakisaka, Yoshinari; Masuzawa, Toru; Tatsumi, Eisuke; Toda, Koichi; Miyazaki, Koji; Eya, Kazuhiro; Baba, Yuzo; Nakatani, Takeshi; Ohno, Takashi; Nishimura, Takashi; Takano, Hisateru

    1996-05-01

    A centrifugal pump with a unique structure has been developed for chronic support. The pump is driven by a magnetic coupling and has no rotating shaft, no seal around the rotating part, and a balancing hole at the center of the impeller and the thrust bearing. The pump was improved in stepwise fashion to realize good antithrombogenicity and low hemolysis. The first pump, the National Cardiovascular Center (NCVC)-O, had an impeller with 4 rectangular and curved vanes; 6 triangularly shaped curved vanes were employed in the second model, the NCVC-1, to reduce trauma to the blood. In the third design, the NCVC-2, the central hole was enlarged, and the thrust bearing shoulder was rounded so that blood washing was enhanced around the impeller; stream lines also were smoothed for improved antithrombogenicity. The hemolytic property of the device was evaluated in vitro with heparinized fresh goat blood; hemolysis indexes of the NCVC-0, -1, and -2 were 0.05, 0.01, and 0.006 g per 100 L, respectively. Antithrombogenicity of the pumps was examined in animal experiments as a left heart bypass device in goats weighing 52-75 kg. Six NCVC-0 pumps were driven for 14 to 33 (22.0 ± 7.6) days in goats receiving the antiplatelet drug cilostazol orally. Four NCVC-I pumps ran for 1 to 80 (28.5 ± 30.6) days with the same drug regimen in 2 cases and with no anticoagulation therapy in 2 cases. After 3 preliminary 1-week tests of NCVC-2 pumps in animals, the pump was installed in 3 goats; 2 pumps were still running on the 182nd and 58th pumping day. Intracorporeal implantation also was attempted successfully. The results indicate that this pump has promising features for chronic support although longer term and additional evaluations are necessary. © 1996 International Society for Artificial Organs.

  18. Development of a centrifugal pump with improved antithrombogenicity and hemolytic property for chronic circulatory support.

    PubMed

    Taenaka, Y; Wakisaka, Y; Masuzawa, T; Tatsumi, E; Toda, K; Miyazaki, K; Eya, K; Baba, Y; Nakatani, T; Ohno, T; Nishimura, T; Takano, H

    1996-06-01

    A centrifugal pump with a unique structure has been developed for chronic support. The pump is driven by a magnetic coupling and has no rotating shaft, no seal around the rotating part, and a balancing hole at the center of the impeller and the thrust bearing. The pump was improved in stepwise fashion to realize good antithrombogenicity and low hemolysis. The first pump, the National Cardiovascular Center (NCVC)-0, had an impeller with 4 rectangular and curved vanes; 6 triangularly shaped curved vanes were employed in the second model, the NCVC-1, to reduce trauma to the blood. In the third design, the NCVC-2, the central hole was enlarged, and the thrust bearing shoulder was rounded so that blood washing was enhanced around the impeller; stream lines also were smoothed for improved antithrombogenicity. The hemolytic property of the device was evaluated in vitro with heparinized fresh goat blood; hemolysis indexes of the NCVC-0, -1, and -2 were 0.05, 0.01, and 0.006 g per 100 L, respectively. Antithrombogenicity of the pumps was examined in animal experiments as a left heart bypass device in goals weighing 52-75 kg. Six NCVC-0 pumps were driven for 14 to 33 (22.0 +/- 7.6) days in goats receiving the antiplatelet drug cilostazol orally. Four NCVC-1 pumps ran for 1 to 80 (28.5 +/- 30.6) days with the same drug regimen in 2 cases and with no anticoagulation therapy in 2 cases. After 3 preliminary 1-week tests of NCVC-2 pumps in animals, the pump was installed in 3 goats; 2 pumps were still running on the 182nd and 58th pumping day. Intracorporeal implantation also was attempted successfully. The results indicate that this pump has promising features for chronic support although longer term and additional evaluations are necessary.

  19. Exergy analysis of electrically- and thermally-driven engines to drive heat pumps: An exhaustive comparative study

    DOE PAGES

    Ally, Moonis R.; Sharma, Vishaldeep; Abdelaziz, Omar

    2017-02-21

    The choice of driving a heat pump with an electrically$-$or a thermally-driven engine is a vexing question complicated by the carbon footprint and environmental impact of using electricity versus natural gas (or waste heat) as the main driver for the respective engines. The amount of useful work generated by these two distinct engines is the focal point of this paper, which addresses a key question: which engine presents a better choice for a given heat pumping application within the constraints of energy and environmental stewardship? Extensive use of energy, exergy, and availability analysis is necessary to quantify the useful workmore » and to examine the issue holistically for both types of engines. The methodology explains why the output of work from these two distinct engines to satisfy a given load is vastly different, a direct consequence of their inherent Irreversibility. Thermodynamic consistency is guaranteed by satisfaction of the First and Second Laws applied to closed systems and their subsystems. The general conclusion is that thermally-driven engines are not industrious converters of heat to mechanical work.« less

  20. Preliminary study of a gas burner-driven and ground-coupled heat pump system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hsu, P.F.

    1995-12-31

    To address the concerns for higher energy efficiency and the immediate phase out of the chlorofluorocarbons (CFCs), a new gas burner-driven, ground-coupled heat pump (GBGCHP) system is proposed for study. The new system is energy efficient and pose no environmental problem. There are three unique features in the proposed system: (1) a patented gas burner-driven compressor with a floating diaphragm piston-cylinder for energy efficiency and accommodating variable load, (2) the ground coupled water-to-air heat exchangers for high coefficient of performance (COPs), and (3) the new refrigerants based on fluoroiodocarbons (FICS) with very little ozone depletion and global warming potential. Amore » preliminary analysis of a prototype heat pump with 3 ton (10.55 kW) heating capacity is presented. The thermodynamics analysis of the system shows that the steady state COP rating higher than 7 is possible with the system operating in heating mode. Additional research work for the GBGCHP system, especially the FICs` thermodynamic properties in the superheated region, is also described.« less

  1. Exergy analysis of electrically- and thermally-driven engines to drive heat pumps: An exhaustive comparative study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ally, Moonis R.; Sharma, Vishaldeep; Abdelaziz, Omar

    The choice of driving a heat pump with an electrically$-$or a thermally-driven engine is a vexing question complicated by the carbon footprint and environmental impact of using electricity versus natural gas (or waste heat) as the main driver for the respective engines. The amount of useful work generated by these two distinct engines is the focal point of this paper, which addresses a key question: which engine presents a better choice for a given heat pumping application within the constraints of energy and environmental stewardship? Extensive use of energy, exergy, and availability analysis is necessary to quantify the useful workmore » and to examine the issue holistically for both types of engines. The methodology explains why the output of work from these two distinct engines to satisfy a given load is vastly different, a direct consequence of their inherent Irreversibility. Thermodynamic consistency is guaranteed by satisfaction of the First and Second Laws applied to closed systems and their subsystems. The general conclusion is that thermally-driven engines are not industrious converters of heat to mechanical work.« less

  2. From diffusion pumps to cryopumps: The conversion of GSFC's space environment simulator

    NASA Technical Reports Server (NTRS)

    Cary, Ron

    1992-01-01

    The SES (Space Environmental Simulator), largest of the Thermal Vacuum Facilities at The Goddard Space Flight Center, recently was converted from an oil diffusion pumped chamber to a Cryopumped chamber. This modification was driven by requirements of flight projects. The basic requirement was to retain or enhance the operational parameters of the chamber such as pumping speed, ultimate vacuum, pump down time, and thermal system performance. To accomplish this task, seventeen diffusion pumps were removed and replaced with eight 1.2 meter (48 inch) diameter cryopumps and one 0.5 meter (20 inch) turbomolecular pump. The conversion was accomplished with a combination of subcontracting and in-house efforts to maximize the efficiency of implementation.

  3. Epididymosomes: transfer of fertility-modulating proteins to the sperm surface

    PubMed Central

    Martin-DeLeon, Patricia A

    2015-01-01

    A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation. These proteins serve roles in immunoprotection and in key steps of fertilization such as capacitation, acrosomal exocytosis and sperm-egg interactions. Their acquisition on sperm cells is mediated both by membrane vesicles (epididymosomes, EP) which were first reported to dock on the sperm surface, and by lipid carriers which facilitate the transfer of proteins associated with the membrane-free fraction of ELF. While the nonvesicular fraction is more efficient, both pathways are dependent on hydrophobic interactions between the GPI-anchor and the external lipid layer of the sperm surface. More recently proteomic and hypothesis-driven studies have shown that EP from several mammals carry transmembrane (TM) proteins, including plasma membrane Ca2+-ATPase 4 (PMCA4). Synthesized in the testis, PMCA4 is an essential protein and the major Ca2+ efflux pump in murine spermatozoa. Delivery of PMCA4 to spermatozoa from bovine and mouse EP during epididymal maturation and in vitro suggests that the docking of EP on the sperm surface precedes fusion, and experimental evidence supports a fusogenic mechanism for TM proteins. Fusion is facilitated by CD9, which generates fusion–competent sites on membranes. On the basis of knowledge of PMCA4's interacting partners a number of TM and membrane-associated proteins have been identified or are predicted to be present, in the epididymosomal cargo deliverable to spermatozoa. These Ca2+-dependent proteins, undetected in proteomic studies, play essential roles in sperm motility and fertility, and their detection highlights the usefulness of the hypothesis-driven approach. PMID:26112481

  4. Epididymosomes: transfer of fertility-modulating proteins to the sperm surface.

    PubMed

    Martin-DeLeon, Patricia A

    2015-01-01

    A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation. These proteins serve roles in immunoprotection and in key steps of fertilization such as capacitation, acrosomal exocytosis and sperm-egg interactions. Their acquisition on sperm cells is mediated both by membrane vesicles (epididymosomes, EP) which were first reported to dock on the sperm surface, and by lipid carriers which facilitate the transfer of proteins associated with the membrane-free fraction of ELF. While the nonvesicular fraction is more efficient, both pathways are dependent on hydrophobic interactions between the GPI-anchor and the external lipid layer of the sperm surface. More recently proteomic and hypothesis-driven studies have shown that EP from several mammals carry transmembrane (TM) proteins, including plasma membrane Ca 2 + -ATPase 4 (PMCA4). Synthesized in the testis, PMCA4 is an essential protein and the major Ca 2 + efflux pump in murine spermatozoa. Delivery of PMCA4 to spermatozoa from bovine and mouse EP during epididymal maturation and in vitro suggests that the docking of EP on the sperm surface precedes fusion, and experimental evidence supports a fusogenic mechanism for TM proteins. Fusion is facilitated by CD9, which generates fusion-competent sites on membranes. On the basis of knowledge of PMCA4's interacting partners a number of TM and membrane-associated proteins have been identified or are predicted to be present, in the epididymosomal cargo deliverable to spermatozoa. These Ca 2 + -dependent proteins, undetected in proteomic studies, play essential roles in sperm motility and fertility, and their detection highlights the usefulness of the hypothesis-driven approach.

  5. Directed and persistent movement arises from mechanochemistry of the ParA/ParB system.

    PubMed

    Hu, Longhua; Vecchiarelli, Anthony G; Mizuuchi, Kiyoshi; Neuman, Keir C; Liu, Jian

    2015-12-22

    The segregation of DNA before cell division is essential for faithful genetic inheritance. In many bacteria, segregation of low-copy number plasmids involves an active partition system composed of a nonspecific DNA-binding ATPase, ParA, and its stimulator protein ParB. The ParA/ParB system drives directed and persistent movement of DNA cargo both in vivo and in vitro. Filament-based models akin to actin/microtubule-driven motility were proposed for plasmid segregation mediated by ParA. Recent experiments challenge this view and suggest that ParA/ParB system motility is driven by a diffusion ratchet mechanism in which ParB-coated plasmid both creates and follows a ParA gradient on the nucleoid surface. However, the detailed mechanism of ParA/ParB-mediated directed and persistent movement remains unknown. Here, we develop a theoretical model describing ParA/ParB-mediated motility. We show that the ParA/ParB system can work as a Brownian ratchet, which effectively couples the ATPase-dependent cycling of ParA-nucleoid affinity to the motion of the ParB-bound cargo. Paradoxically, this resulting processive motion relies on quenching diffusive plasmid motion through a large number of transient ParA/ParB-mediated tethers to the nucleoid surface. Our work thus sheds light on an emergent phenomenon in which nonmotor proteins work collectively via mechanochemical coupling to propel cargos-an ingenious solution shaped by evolution to cope with the lack of processive motor proteins in bacteria.

  6. 50. (Credit JTL) Locomotivetype steam driven air compressor built by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. (Credit JTL) Locomotive-type steam driven air compressor built by Westinghouse Air Brake Company and located on west wall of old high service room. - McNeil Street Pumping Station, McNeil Street & Cross Bayou, Shreveport, Caddo Parish, LA

  7. [Improved design of permanent maglev impeller assist heart].

    PubMed

    Qian, Kunxi; Zeng, Pei; Ru, Weimin; Yuan, Haiyu

    2002-12-01

    Magnetic bearing has no mechanical contact between the rotor and stator. And a rotary pump with magnetic bearing has therefore no mechanical wear and thrombosis due to bearing. The available magnetic bearings, however, are devised with electric magnets, need complicated control and remarkable energy consumption. Resultantly, it is difficult to apply an electric magnetic bearing to rotary pump without disturbing its simplicity, implantability and reliability. The authors have developed a levitated impeller pump merely with permanent magnets. The rotor is supported by permanent magnetic forces radially. On one side of the rotor, the impeller is fixed; and on the other side of the rotor, the driven magnets are mounted. Opposite to this driven magnets, a driving motor coil with iron corn magnets is fastened to the motor axis. Thereafter, the motor drives the rotor via a rotating magnetic field. By laboratory tests with saline, if the rotor stands still or rotates under 4,000 rpm, the rotor has one-point contact axially with the driving motor coil. The contacting point is located in the center of the rotor. As the rotating speed increases gradually to more than 4,000 rpm, the rotor will detache from the stator axially. Then the rotor will be fully levitated. Since the axial levitation is produced by hydraulic force and the driven magnets have a gyro-effect, the rotor rotates very steadly during levitation. As a left ventricular assist device, the pump works in a rotating speed range of 5,000-8,000 rpm, the levitation of the impeller hence is ensured by practical use of the pump.

  8. Design, manufacture, and test of coolant pump-motor assembly for Brayton power conversion system

    NASA Technical Reports Server (NTRS)

    Gabacz, L. E.

    1973-01-01

    The design, development, fabrication, and testing of seven coolant circulating pump-motor assemblies are discussed. The pump-motor assembly is driven by the nominal 44.4-volt, 400-Hz, 3-phase output of a nominal 56-volt dc input inverter. The pump-motor assembly will be used to circulate Dow Corning 200 liquid coolant for use in a Brayton cycle space power system. The pump-motor assembly develops a nominal head of 70 psi at 3.7 gpm with an over-all efficiency of 26 percent. The design description, drawings, photographs, reliability results, and developmental and acceptance test results are included.

  9. 46 CFR 108.415 - Fire pump: General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... have at least two independently driven fire pumps that can each deliver water at a continuous pitot tube pressure of at least 3.5 kilograms per square centimeter (approximately 50 pounds per square inch) at least two fire hose nozzles that are connected to the highest two fire hydrants on the unit...

  10. 46 CFR 108.415 - Fire pump: General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... have at least two independently driven fire pumps that can each deliver water at a continuous pitot tube pressure of at least 3.5 kilograms per square centimeter (approximately 50 pounds per square inch) at least two fire hose nozzles that are connected to the highest two fire hydrants on the unit...

  11. 46 CFR 108.415 - Fire pump: General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... have at least two independently driven fire pumps that can each deliver water at a continuous pitot tube pressure of at least 3.5 kilograms per square centimeter (approximately 50 pounds per square inch) at least two fire hose nozzles that are connected to the highest two fire hydrants on the unit...

  12. 46 CFR 108.415 - Fire pump: General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... have at least two independently driven fire pumps that can each deliver water at a continuous pitot tube pressure of at least 3.5 kilograms per square centimeter (approximately 50 pounds per square inch) at least two fire hose nozzles that are connected to the highest two fire hydrants on the unit...

  13. 46 CFR 108.415 - Fire pump: General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... have at least two independently driven fire pumps that can each deliver water at a continuous pitot tube pressure of at least 3.5 kilograms per square centimeter (approximately 50 pounds per square inch) at least two fire hose nozzles that are connected to the highest two fire hydrants on the unit...

  14. Twin-spool turbopumps for ''low'' net positive suction pressure operations

    NASA Technical Reports Server (NTRS)

    Bair, E. K.; Campbell, W. E.; Ford, O. I.

    1970-01-01

    Modified single-shaft turbopump incorporates inducer and main pump, each separately driven at different speeds through coaxial-shaft arrangement. Inducer operates at low speed for low net positive suction pressure, main pump operates at high speed to generate high pressure. This arrangement requires no external control for the inducer.

  15. Improved Design Process Part of the Ship Producibility Program of the National Shipbuilding Research Program

    DTIC Science & Technology

    1977-04-01

    Exh and Escape Fresh Water Feed Treatment Cargo Oil Tank Cleaning Diesel Generator Piping Piping Material Schedule List of Motors and... tank length frame and stiffener spacing, etc. One yard buys only mill edge plates, and one yard buys only cold flange quality plates. 2-13 C. POST...gage boards, all interconnecting piping and valves, and all mounted on a common foundation, or a pump room assembled on a tank top unit. Use of packages

  16. Modification of ocean-estuary salt fluxes by density-driven advection of a headland eddy

    NASA Astrophysics Data System (ADS)

    Fram, J. P.; Stacey, M. T.

    2005-05-01

    Scalar exchange between San Francisco Bay and the coastal ocean is examined using shipboard observations made across the Golden Gate Channel. Ocean-estuary exchange is often described as a combination of two independent types of mechanisms: density-driven exchange such as gravitational circulation and tidal asymmetries such as tidal trapping. In this study we found that exchange is also governed by an interaction between these mechanisms. Tidally trapped eddies created in shallow shoals are mixed into the main channel earlier in the tidal cycle during the rainy season because the eddies are pushed seaward by gravitational circulation. This interaction increases the tidally averaged dispersive salt flux into the bay. The study consists of experiments during each of three 'seasons': winter/spring runoff (March 2002), summer upwelling (July 2003), and fall relaxation (October 2002). Within each experiment, transects across the channel were repeated approximately every 12 minutes for 25 hours during both spring tide and the following neap tide. Velocity was measured from a boat-mounted ADCP. Scalar concentrations were measured from a tow-yoed SeaSciences Acrobat. Salinity exchange over each spring-neap cycle is quantified with harmonic analysis. Harmonic results are decomposed into flux mechanisms using temporal and spatial correlations. The temporal correlation of cross-sectional averaged salinity and velocity (tidal pumping flux) is the largest part of the dispersive flux of salinity into the bay. From the tidal pumping portion of the dispersive flux, it is shown that there is less exchange than was found in earlier studies. Furthermore, tidal pumping flux scales strongly with flow due to density-driven movement of tidally trapped eddies and density-driven increases in ebb-flood frictional phasing. Complex bathymetry makes salinity exchange scale differently with flow than would be expected from simple tidal pumping and gravitational circulation models.

  17. Technology Solutions Case Study: Field Performance of Inverter-Driven Heat Pumps in Cold Climates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. Williamson and R. Aldrich

    2015-09-01

    To better understand and characterize heating performance, the U.S. Department of Energy Building America team, Consortium for Advanced Residential Buildings (CARB), monitored seven inverter-driven ASHPs across the northeast United States during the winter of 2013–2014.

  18. Resonantly photo-pumped nickel-like erbium X-ray laser

    DOEpatents

    Nilsen, Joseph

    1990-01-01

    A resonantly photo-pumped X-ray laser (10) that enhances the gain of seve laser lines that also lase because of collisional excitations and recombination processes, is described. The laser comprises an aluminum (12) and erbium (14) foil combination (16) that is driven by two beams (18, 20) of intense line focused (22, 24) optical laser radiation. Ground state nickel-like erbium ions (34) are resonantly photo-pumped by line emission from hydrogen-like aluminum ions (32).

  19. Control of a rotary pulsatile cardiac assist pump driven by an electric motor without a pressure sensor to avoid collapse of the pump inlet.

    PubMed

    Trinkl, J; Havlik, P; Mesana, T; Mitsui, N; Morita, S; Demunck, J L; Tourres, J L; Monties, J R

    1993-01-01

    Our ventricular assist device uses a valveless volumetric pump operating on the Maillard-Wankel rotary principle. It is driven by an electric motor and provides a semi pulsatile flow. At each cycle, blood is actively aspirated into the device, and overpumping results in collapse at the pump inlet. To prevent overpumping, it is necessary to ensure that pump intake does not exceed venous return. Poor long-term reliability rules out the use of current implantable pressure sensors for this purpose. To resolve this problem, we have developed a method of control based on monitoring of the intensity of electric current consumed by the motor. The method consists of real time monitoring of current intensity at the beginning of each pump cycle. A sudden change in intensity indicates underfilling, and motor speed is reduced to prevent collapse. The current consumed by the motor also depends on the afterload, but the form of the signal remains the same when afterload changes. After demonstrating the feasibility of this technique in a simulator, we are now testing it in animals. We were able to detect and prevent collapse due to overpumping by the cardiac assist device. This system also enables us to know the maximum possible assistance and to thus adapt assistance to the user.

  20. Ocean Fertilization for Sequestration of Carbon Dioxide from the Atmosphere

    NASA Astrophysics Data System (ADS)

    Boyd, Philip W.

    The ocean is a major sink for both preindustrial and anthropogenic carbon dioxide. Both physically and biogeochemically driven pumps, termed the solubility and biological pump, respectively Fig.5.1) are responsible for the majority of carbon sequestration in the ocean's interior [1]. The solubility pump relies on ocean circulation - specifically the impact of cooling of the upper ocean at high latitudes both enhances the solubility of carbon dioxide and the density of the waters which sink to great depth (the so-called deepwater formation) and thereby sequester carbon in the form of dissolved inorganic carbon (Fig.5.1). The biological pump is driven by the availability of preformed plant macronutrients such as nitrate or phosphate which are taken up by phytoplankton during photosynthetic carbon fixation. A small but significant proportion of this fixed carbon sinks into the ocean's interior in the form of settling particles, and in order to maintain equilibrium carbon dioxide from the atmosphere is transferred across the air-sea interface into the ocean (the so-called carbon drawdown) thereby decreasing atmospheric carbon dioxide (Fig.5.1).Fig.5.1

  1. F"orster-type mechanism of the redox-driven proton pump

    NASA Astrophysics Data System (ADS)

    Mourokh, Lev; Smirnov, Anatoly; Nori, Franco

    2007-03-01

    We propose a model to describe an electronically-driven proton pump in the cytochrome c oxidase (CcO). We examine the situation when the electron transport between the two sites embedded into the inner membrane of the mitochondrion occurs in parallel with the proton transfer from the protonable site that is close to the negative (inner) side of the membrane to the other protonable site located nearby the positive (outer) surface of the membrane. In addition to the conventional electron and proton tunnelings between the sites, the Coulomb interaction between electrons and protons localized on the corresponding sites leads to so-called F"orster transfer, i.e. to the process when the simultaneous electron and proton tunnelings are accompanied by the resonant energy transfer between the electrons and protons. Our calculations based on reasonable parameters have demonstrated that the F"orster process facilitates the proton pump at physiological temperatures. We have examined the effects of an electron voltage build-up, external temperature, and molecular electrostatics driving the electron and proton energies to the resonant conditions, and have shown that these parameters can control the proton pump operation.

  2. Advanced solar energy conversion. [solar pumped gas lasers

    NASA Technical Reports Server (NTRS)

    Lee, J. H.

    1981-01-01

    An atomic iodine laser, a candidate for the direct solar pumped lasers, was successfully excited with a 4 kW beam from a xenon arc solar simulator, thus proving the feasibility of the concept. The experimental set up and the laser output as functions of operating conditions are presented. The preliminary results of the iodine laser amplifier pumped with the HCP array to which a Q switch for giant pulse production was coupled are included. Two invention disclosures - a laser driven magnetohydrodynamic generator for conversion of laser energy to electricity and solar pumped gas lasers - are also included.

  3. Effect of additional optical pumping injection into the ground-state ensemble on the gain and the phase recovery acceleration of quantum-dot semiconductor optical amplifiers

    NASA Astrophysics Data System (ADS)

    Kim, Jungho

    2014-02-01

    The effect of additional optical pumping injection into the ground-state ensemble on the ultrafast gain and the phase recovery dynamics of electrically-driven quantum-dot semiconductor optical amplifiers is numerically investigated by solving 1088 coupled rate equations. The ultrafast gain and the phase recovery responses are calculated with respect to the additional optical pumping power. Increasing the additional optical pumping power can significantly accelerate the ultrafast phase recovery, which cannot be done by increasing the injection current density.

  4. Power- or frequency-driven hysteresis for continuous-wave optically injected distributed-feedback semiconductor lasers.

    PubMed

    Blin, Stéphane; Vaudel, Olivier; Besnard, Pascal; Gabet, Renaud

    2009-05-25

    Bistabilities between a steady (or pulsating, chaotic) and different pulsating regimes are investigated for an optically injected semi-conductor laser. Both numerical and experimental studies are reported for continuous-wave single-mode semiconductor distributed-feedback lasers emitting at 1.55 microm. Hysteresis are driven by either changing the optically injected power or the frequency difference between both lasers. The effect of the injected laser pumping rate is also examined. Systematic mappings of the possible laser outputs (injection locking, bimodal, wave mixing, chaos or relaxation oscillations) are carried out. At small pumping rates (1.2 times threshold), only locking and bimodal regimes are observed. The extent of the bistable area is either 11 dB or 35 GHz, depending on the varying parameters. At high pumping rates (4 times threshold), numerous injection regimes are observed. Injection locking and its bistabilities are also reported for secondary longitudinal modes.

  5. Quantum statistics and squeezing for a microwave-driven interacting magnon system.

    PubMed

    Haghshenasfard, Zahra; Cottam, Michael G

    2017-02-01

    Theoretical studies are reported for the statistical properties of a microwave-driven interacting magnon system. Both the magnetic dipole-dipole and the exchange interactions are included and the theory is developed for the case of parallel pumping allowing for the inclusion of the nonlinear processes due to the four-magnon interactions. The method of second quantization is used to transform the total Hamiltonian from spin operators to boson creation and annihilation operators. By using the coherent magnon state representation we have studied the magnon occupation number and the statistical behavior of the system. In particular, it is shown that the nonlinearities introduced by the parallel pumping field and the four-magnon interactions lead to non-classical quantum statistical properties of the system, such as magnon squeezing. Also control of the collapse-and-revival phenomena for the time evolution of the average magnon number is demonstrated by varying the parallel pumping amplitude and the four-magnon coupling.

  6. Device and method to relieve cordelle action in a chain driven pump

    DOEpatents

    Dysarz, Edward D.

    1994-01-01

    A cordelle action relief apparatus or device for use in sucker rod pumps in a petroleum or water well. The device is incorporated in a chain driven pump to prevent the chain from forming a bow or archlike configuration as the chain rolls off of the sprocket and down into the well. When the chain is allowed to form this bow or arch it could damage the well and well casing. The device includes a first rod on the side of the chain and a second rod on the second side of the chain that will allow the rollers of the chain to roll on the rod and further prevent the chain from bowing or arching and will further allow the rollers on the chain to roll on the rods which will further prevent damage to the well casing, the well, and the chain.

  7. Japanese power electronics inverter technology and its impact on the American air conditioning industry

    NASA Astrophysics Data System (ADS)

    Ushimaru, Kenji

    1990-08-01

    Since 1983, technological advances and market growth of inverter-driven variable-speed heat pumps in Japan have been dramatic. The high level of market penetration was promoted by a combination of political, economic, and trade policies in Japan. A unique environment was created in which the leading domestic industries, microprocessor manufacturing, compressors for air conditioning and refrigerators, and power electronic devices, were able to direct the development and market success of inverter-driven heat pumps. As a result, leading U.S. variable-speed heat pump manufacturers should expect a challenge from the Japanese producers of power devices and microprocessors. Because of the vertically-integrated production structure in Japan, in contrast to the out-sourcing culture of the United States, price competition at the component level (such as inverters, sensors, and controls) may impact the structure of the industry more severely than final product sales.

  8. Detection of pure inverse spin-Hall effect induced by spin pumping at various excitation

    NASA Astrophysics Data System (ADS)

    Inoue, H. Y.; Harii, K.; Ando, K.; Sasage, K.; Saitoh, E.

    2007-10-01

    Electric-field generation due to the inverse spin-Hall effect (ISHE) driven by spin pumping was detected and separated experimentally from the extrinsic magnetogalvanic effects in a Ni81Fe19/Pt film. By applying a sample-cavity configuration in which the extrinsic effects are suppressed, the spin pumping using ferromagnetic resonance gives rise to a symmetric spectral shape in the electromotive force spectrum, indicating that the motive force is due entirely to ISHE. This method allows the quantitative analysis of the ISHE and the spin-pumping effect. The microwave-power dependence of the ISHE amplitude is consistent with the prediction of a direct current-spin-pumping scenario.

  9. Vibrational pumping and heating under SERS conditions: fact or myth?

    PubMed

    Le Ru, E C; Etchegoin, P G

    2006-01-01

    We address in this paper the long debated issue of the possibility of vibrational pumping under Surface Enhanced Raman Scattering (SERS) conditions, both theoretically and experimentally. We revisit with simple theoretical models the mechanisms of vibrational pumping and its relation to heating. This presentation provides a clear classification of the various regimes of heating/pumping, from simple global laser heating to selective pumping of a single vibrational mode. We also propose the possibility of extreme pumping driven by stimulated phonon emission, and we introduce and apply a new experimental technique to study these effects in SERS. Our method relies on correlations between Raman peak parameters, and cross-correlation for two Raman peaks. We find strong evidence for local and dynamical heating, but no convincing evidence for selective pumping under our specific experimental SERS conditions.

  10. IEA HPT ANNEX 41 – Cold climate heat pumps: US country report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Groll, Eckhard A.; Baxter, Van D.

    In 2012 the International Energy Agency (IEA) Heat Pump Programme (now the Heat Pump Technologies (HPT) program) established Annex 41 to investigate technology solutions to improve performance of heat pumps for cold climates. Four IEA HPT member countries are participating in the Annex – Austria, Canada, Japan, and the United States (U.S.). The principal focus of Annex 41 is on electrically driven air-source heat pumps (ASHP) since that system type has the lowest installation cost of all heat pump alternatives. They also have the most significant performance challenges given their inherent efficiency and capacity issues at cold outdoor temperatures. Availabilitymore » of ASHPs with improved low ambient performance would help bring about a much stronger heat pump market presence in cold areas, which today rely predominantly on fossil fuel furnace heating systems.« less

  11. Pathways of proton transfer in the light-driven pump bacteriorhodopsin

    NASA Technical Reports Server (NTRS)

    Lanyi, J. K.

    1993-01-01

    The mechanism of proton transport in the light-driven pump bacteriorhodopsin is beginning to be understood. Light causes the all-trans to 13-cis isomerization of the retinal chromophore. This sets off a sequential and directed series of transient decreases in the pKa's of a) the retinal Schiff base, b) an extracellular proton release complex which includes asp-85, and c) a cytoplasmic proton uptake complex which includes asp-96. The timing of these pKa changes during the photoreaction cycle causes sequential proton transfers which result in the net movement of a proton across the protein, from the cytoplasmic to the extracellular surface.

  12. White-light parametric instabilities in plasmas.

    PubMed

    Santos, J E; Silva, L O; Bingham, R

    2007-06-08

    Parametric instabilities driven by partially coherent radiation in plasmas are described by a generalized statistical Wigner-Moyal set of equations, formally equivalent to the full wave equation, coupled to the plasma fluid equations. A generalized dispersion relation for stimulated Raman scattering driven by a partially coherent pump field is derived, revealing a growth rate dependence, with the coherence width sigma of the radiation field, scaling with 1/sigma for backscattering (three-wave process), and with 1/sigma1/2 for direct forward scattering (four-wave process). Our results demonstrate the possibility to control the growth rates of these instabilities by properly using broadband pump radiation fields.

  13. Enhancement of survival and electricity production in an engineered bacterium by light-driven proton pumping.

    PubMed

    Johnson, Ethan T; Baron, Daniel B; Naranjo, Belén; Bond, Daniel R; Schmidt-Dannert, Claudia; Gralnick, Jeffrey A

    2010-07-01

    Microorganisms can use complex photosystems or light-dependent proton pumps to generate membrane potential and/or reduce electron carriers to support growth. The discovery that proteorhodopsin is a light-dependent proton pump that can be expressed readily in recombinant bacteria enables development of new strategies to probe microbial physiology and to engineer microbes with new light-driven properties. Here, we describe functional expression of proteorhodopsin and light-induced changes in membrane potential in the bacterium Shewanella oneidensis strain MR-1. We report that there were significant increases in electrical current generation during illumination of electrochemical chambers containing S. oneidensis expressing proteorhodopsin. We present evidence that an engineered strain is able to consume lactate at an increased rate when it is illuminated, which is consistent with the hypothesis that proteorhodopsin activity enhances lactate uptake by increasing the proton motive force. Our results demonstrate that there is coupling of a light-driven process to electricity generation in a nonphotosynthetic engineered bacterium. Expression of proteorhodopsin also preserved the viability of the bacterium under nutrient-limited conditions, providing evidence that fulfillment of basic energy needs of organisms may explain the widespread distribution of proteorhodopsin in marine environments.

  14. Study toward high-performance thermally driven air-conditioning systems

    NASA Astrophysics Data System (ADS)

    Miyazaki, Takahiko; Miyawaki, Jin; Ohba, Tomonori; Yoon, Seong-Ho; Saha, Bidyut Baran; Koyama, Shigeru

    2017-01-01

    The Adsorption heat pump is a technology for cooling and heating by using hot water as a driving heat source. It will largely contribute to energy savings when it is driven by solar thermal energy or waste heat. The system is available in the market worldwide, and there are many examples of application to heat recovery in factories and to solar cooling systems. In the present system, silica gel and zeolite are popular adsorbents in combination with water refrigerant. Our study focused on activated carbon-ethanol pair for adsorption cooling system because of the potential to compete with conventional systems in terms of coefficient of performance. In addition, activated-ethanol pair can generally produce larger cooling effect by an adsorption-desorption cycle compared with that of the conventional pairs in terms of cooling effect per unit adsorbent mass. After the potential of a commercially available activated carbon with highest level specific surface area was evaluated, we developed a new activated carbon that has the optimum pore characteristics for the purpose of solar or waste heat driven cooling systems. In this paper, comparison of refrigerants for adsorption heat pump application is presented, and a newly developed activated carbon for ethanol adsorption heat pump is introduced.

  15. Do Europa's Mountains Have Roots? Erosion of Topography at the Ice-Water Interface via the "Ice Pump"

    NASA Astrophysics Data System (ADS)

    Goodman, J. C.

    2016-12-01

    Are topographic features on the surface of Europa and other icy worlds isostatically compensated by variations in shell thickness (Airy isostasy)? This is only possible if variations in shell thickness can remain stable over geologic time. Here we show that melting and freezing driven by the pressure dependence of the melting point of water - the "ice pump" - can rapidly erase topography at the ice/water interface. We consider ice pumps driven by both tidal action and buoyancy-driven flow. We first show that as tidal action drives the ocean up and down along a sloping interface, ice will be melted from areas where it's thickest and deposited where the ice is thinnest. We show that this process causes the ice interface topography to relax according to a simple "diffusion" linear partial differential equation. We estimate that a 10-km-wide topographic feature would be erased by the tidal ice pump in 3000 years if Europa's tidal current amplitude is 1 cm/s; however, this timescale is inversely proportional to the cube of the tidal velocity! Next, we consider an ice pump powered by ascent of meltwater along a sloping ice-water interface. We consider layer-averaged budgets for heat, mass, and momentum, along with turbulent mixing of the meltwater layer with underlying seawater via a Richardson number dependent entrainment process, and use these to estimate the thickness and mass flux of the meltwater layer. From this we estimate the rate of melting and freezing at the interface. These two ice pump processes combine with the glacial flow of warm basal ice to rapidly flatten out any variations in the height of the ice-water interface: Europa's ice/water interface may be perfectly flat! If so, topography at Europa's surface can only be supported by variations in density of the shell or the strength of the brittle surface ice.

  16. Waste-Heat-Driven Cooling Using Complex Compound Sorbents

    NASA Technical Reports Server (NTRS)

    Rocketfeller, Uwe; Kirol, Lance; Khalili, Kaveh

    2004-01-01

    Improved complex-compound sorption pumps are undergoing development for use as prime movers in heat-pump systems for cooling and dehumidification of habitats for humans on the Moon and for residential and commercial cooling on Earth. Among the advantages of sorption heat-pump systems are that they contain no moving parts except for check valves and they can be driven by heat from diverse sources: examples include waste heat from generation of electric power, solar heat, or heat from combustion of natural gas. The use of complex compound sorbents in cooling cycles is not new in itself: Marketing of residential refrigerators using SrCl2 was attempted in the 1920s and 30s and was abandoned because heat- and mass-transfer rates of the sorbents were too low. Addressing the issue that gave rise to the prior abandonment of complex compound sorption heat pumps, the primary accomplishment of the present development program thus far has been the characterization of many candidate sorption media, leading to large increases in achievable heat- and mass-transfer rates. In particular, two complex compounds (called "CC260-1260" and "CC260-2000") were found to be capable of functioning over the temperature range of interest for the lunar-habitat application and to offer heat- and mass-transfer rates and a temperature-lift capability adequate for that application. Regarding the temperature range: A heat pump based on either of these compounds is capable of providing a 95-K lift from a habitable temperature to a heat-rejection (radiator) temperature when driven by waste heat at an input temperature .500 K. Regarding the heat- and mass-transfer rates or, more precisely, the power densities made possible by these rates: Power densities observed in tests were 0.3 kilowatt of cooling per kilogram of sorbent and 2 kilowatts of heating per kilogram of sorbent. A prototype 1-kilowatt heat pump based on CC260-2000 has been built and demonstrated to function successfully.

  17. Velocity pump reaction turbine

    DOEpatents

    House, Palmer A.

    1982-01-01

    An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.

  18. Velocity pump reaction turbine

    DOEpatents

    House, Palmer A.

    1984-01-01

    An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.

  19. Spectral linewidth preservation in parametric frequency combs seeded by dual pumps.

    PubMed

    Tong, Zhi; Wiberg, Andreas O J; Myslivets, Evgeny; Kuo, Bill P P; Alic, Nikola; Radic, Stojan

    2012-07-30

    We demonstrate new technique for generation of programmable-pitch, wideband frequency combs with low phase noise. The comb generation was achieved using cavity-less, multistage mixer driven by two tunable continuous-wave pump seeds. The approach relies on phase-correlated continuous-wave pumps in order to cancel spectral linewidth broadening inherent to parametric comb generation. Parametric combs with over 200-nm bandwidth were obtained and characterized with respect to phase noise scaling to demonstrate linewidth preservation over 100 generated tones.

  20. Velocity pump reaction turbine

    DOEpatents

    House, P.A.

    An expanding hydraulic/two-phase velocity pump reaction turbine including a dual concentric rotor configuration with an inter-rotor annular flow channel in which the inner rotor is mechanically driven by the outer rotor. In another embodiment, the inner rotor is immobilized and provided with gas recovery ports on its outer surface by means of which gas in solution may be recovered. This velocity pump reaction turbine configuration is capable of potential energy conversion efficiencies of up to 70%, and is particularly suited for geothermal applications.

  1. Zigzag laser with reduced optical distortion

    DOEpatents

    Albrecht, G.F.; Comaskey, B.; Sutton, S.B.

    1994-04-19

    The architecture of the present invention has been driven by the need to solve the beam quality problems inherent in Brewster's angle tipped slab lasers. The entrance and exit faces of a solid state slab laser are cut perpendicular with respect to the pump face, thus intrinsically eliminating distortion caused by the unpumped Brewster's angled faces. For a given zigzag angle, the residual distortions inherent in the remaining unpumped or lightly pumped ends may be reduced further by tailoring the pump intensity at these ends. 11 figures.

  2. Zigzag laser with reduced optical distortion

    DOEpatents

    Albrecht, Georg F.; Comaskey, Brian; Sutton, Steven B.

    1994-01-01

    The architecture of the present invention has been driven by the need to solve the beam quality problems inherent in Brewster's angle tipped slab lasers. The entrance and exit faces of a solid state slab laser are cut perpendicular with respect to the pump face, thus intrinsically eliminating distortion caused by the unpumped Brewster's angled faces. For a given zigzag angle, the residual distortions inherent in the remaining unpumped or lightly pumped ends may be reduced further by tailoring the pump intensity at these ends.

  3. Geothermal down well pumping system

    NASA Technical Reports Server (NTRS)

    Matthews, H. B.; Mcbee, W. D.

    1974-01-01

    A key technical problem in the exploitation of hot water geothermal energy resources is down-well pumping to inhibit mineral precipitation, improve thermal efficiency, and enhance flow. A novel approach to this problem involves the use of a small fraction of the thermal energy of the well water to boil and super-heat a clean feedwater flow in a down-hole exchanger adjacent to the pump. This steam powers a high-speed turbine-driven pump. The exhaust steam is brought to the surface through an exhaust pipe, condensed, and recirculated. A small fraction of the high-pressure clean feedwater is diverted to lubricate the turbine pump bearings and prevent leakage of brine into the turbine-pump unit. A project demonstrating the feasibility of this approach by means of both laboratory and down-well tests is discussed.

  4. Advanced Solar-propelled Cargo Spacecraft for Mars Missions

    NASA Technical Reports Server (NTRS)

    Auziasdeturenne, Jacqueline; Beall, Mark; Burianek, Joseph; Cinniger, Anna; Dunmire, Barbrina; Haberman, Eric; Iwamoto, James; Johnson, Stephen; Mccracken, Shawn; Miller, Melanie

    1989-01-01

    Three concepts for an unmanned, solar powered, cargo spacecraft for Mars support missions were investigated. These spacecraft are designed to carry a 50,000 kg payload from a low Earth orbit to a low Mars orbit. Each design uses a distinctly different propulsion system: A Solar Radiation Absorption (SRA) system, a Solar-Pumped Laser (SPL) system and a solar powered magnetoplasmadynamic (MPD) arc system. The SRA directly converts solar energy to thermal energy in the propellant through a novel process. In the SPL system, a pair of solar-pumped, multi-megawatt, CO2 lasers in sunsynchronous Earth orbit converts solar energy to laser energy. The MPD system used indium phosphide solar cells to convert sunlight to electricity, which powers the propulsion system. Various orbital transfer options are examined for these concepts. In the SRA system, the mother ship transfers the payload into a very high Earth orbit and a small auxiliary propulsion system boosts the payload into a Hohmann transfer to Mars. The SPL spacecraft and the SPL powered spacecraft return to Earth for subsequent missions. The MPD propelled spacecraft, however, remains at Mars as an orbiting space station. A patched conic approximation was used to determine a heliocentric interplanetary transfer orbit for the MPD propelled spacecraft. All three solar-powered spacecraft use an aerobrake procedure to place the payload into a low Mars parking orbit. The payload delivery times range from 160 days to 873 days (2.39 years).

  5. A novel miniature dynamic microfluidic cell culture platform using electro-osmosis diode pumping.

    PubMed

    Chang, Jen-Yung; Wang, Shuo; Allen, Jeffrey S; Lee, Seong Hyuk; Chang, Suk Tai; Choi, Young-Ki; Friedrich, Craig; Choi, Chang Kyoung

    2014-07-01

    An electro-osmosis (EOS) diode pumping platform capable of culturing cells in fluidic cellular micro-environments particularly at low volume flow rates has been developed. Diode pumps have been shown to be a viable alternative to mechanically driven pumps. Typically electrokinetic micro-pumps were limited to low-concentration solutions (≤10 mM). In our approach, surface mount diodes were embedded along the sidewalls of a microchannel to rectify externally applied alternating current into pulsed direct current power across the diodes in order to generate EOS flows. This approach has for the first time generated flows at ultra-low flow rates (from 2.0 nl/s to 12.3 nl/s) in aqueous solutions with concentrations greater than 100 mM. The range of flow was generated by changing the electric field strength applied to the diodes from 0.5 Vpp/cm to 10 Vpp/cm. Embedding an additional diode on the upper surface of the enclosed microchannel increased flow rates further. We characterized the diode pump-driven fluidics in terms of intensities and frequencies of electric inputs, pH values of solutions, and solution types. As part of this study, we found that the growth of A549 human lung cancer cells was positively affected in the microfluidic diode pumping system. Though the chemical reaction compromised the fluidic control overtime, the system could be maintained fully functional over a long time if the solution was changed every hour. In conclusion, the advantage of miniature size and ability to accurately control fluids at ultra-low volume flow rates can make this diode pumping system attractive to lab-on-a-chip applications and biomedical engineering in vitro studies.

  6. A novel miniature dynamic microfluidic cell culture platform using electro-osmosis diode pumping

    PubMed Central

    Chang, Jen-Yung; Wang, Shuo; Allen, Jeffrey S.; Lee, Seong Hyuk; Chang, Suk Tai; Choi, Young-Ki; Friedrich, Craig; Choi, Chang Kyoung

    2014-01-01

    An electro-osmosis (EOS) diode pumping platform capable of culturing cells in fluidic cellular micro-environments particularly at low volume flow rates has been developed. Diode pumps have been shown to be a viable alternative to mechanically driven pumps. Typically electrokinetic micro-pumps were limited to low-concentration solutions (≤10 mM). In our approach, surface mount diodes were embedded along the sidewalls of a microchannel to rectify externally applied alternating current into pulsed direct current power across the diodes in order to generate EOS flows. This approach has for the first time generated flows at ultra-low flow rates (from 2.0 nl/s to 12.3 nl/s) in aqueous solutions with concentrations greater than 100 mM. The range of flow was generated by changing the electric field strength applied to the diodes from 0.5 Vpp/cm to 10 Vpp/cm. Embedding an additional diode on the upper surface of the enclosed microchannel increased flow rates further. We characterized the diode pump-driven fluidics in terms of intensities and frequencies of electric inputs, pH values of solutions, and solution types. As part of this study, we found that the growth of A549 human lung cancer cells was positively affected in the microfluidic diode pumping system. Though the chemical reaction compromised the fluidic control overtime, the system could be maintained fully functional over a long time if the solution was changed every hour. In conclusion, the advantage of miniature size and ability to accurately control fluids at ultra-low volume flow rates can make this diode pumping system attractive to lab-on-a-chip applications and biomedical engineering in vitro studies. PMID:25379101

  7. 76 FR 77565 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... assure that the emergency diesel generator's diesel driven cooling water pumps perform their required... generators will provide required electrical power as assumed in the accident analyses and the cooling water... Technical Specifications to require an adequate emergency diesel generator and diesel driven cooling water...

  8. A micro surface tension pump (MISPU) in a glass microchip.

    PubMed

    Peng, Xing Yue Larry

    2011-01-07

    A non-membrane micro surface tension pump (MISPU) was fabricated on a glass microchip by one-step glass etching. It needs no material other than glass and is driven by digital gas pressure. The MISPU can be seen working like a piston pump inside the glass microchip under a microscope. The design of the valves (MISVA) and pistons (MISTON) was based on the surface tension theory of the micro surface tension alveolus (MISTA). The digital gas pressure controls the moving gas-liquid interface to open or close the input and output MISVAs to refill or drive the MISTON for pumping a liquid. Without any moving parts, a MISPU is a kind of long-lasting micro pump for micro chips that does not lose its water pumping efficiency over a 20-day period. The volumetric pump output varied from 0 to 10 nl s(-1) when the pump cycle time decreased from 5 min to 15 s. The pump head pressure was 1 kPa.

  9. Long pulse production from short pulses

    DOEpatents

    Toeppen, J.S.

    1994-08-02

    A method of producing a long output pulse from a short pump pulse is disclosed, using an elongated amplified fiber having a doped core that provides an amplifying medium for light of one color when driven into an excited state by light of a shorter wavelength and a surrounding cladding. A seed beam of the longer wavelength is injected into the core at one end of the fiber and a pump pulse of the shorter wavelength is injected into the cladding at the other end of the fiber. The counter-propagating seed beam and pump pulse will produce an amplified output pulse having a time duration equal to twice the transit time of the pump pulse through the fiber plus the length of the pump pulse. 3 figs.

  10. Experimental Simulation of Turbine-Exhaust Oxygen Recovery

    NASA Technical Reports Server (NTRS)

    Clark, Jim A.; Branch, Ryan W.

    2004-01-01

    In some liquid-propellant rocket engines, the liquid-oxygen boost pump is driven by a turbine that is powered by high-pressure gaseous oxygen. Once it exits the turbine, this gaseous oxygen can be salvaged by injecting it into the subcooled liquid oxygen exiting the boost pump. If the main LOX pump is to function correctly under these circumstances, complete condensation of the gaseous oxygen must quickly follow its injection into the boost-pump discharge. The current investigation uses steam and water in a simple rig that allows the condensation process to be visualized and quantified. This paper offers dimensionless-parameter correlations of the data and trends observed.

  11. All0809/8/7 is a DevBCA-like ABC-type efflux pump required for diazotrophic growth in Anabaena sp. PCC 7120.

    PubMed

    Staron, Peter; Maldener, Iris

    2012-10-01

    Efflux pumps export a wide variety of proteinaceous and non-proteinaceous substrates across the Gram-negative cell wall. For the filamentous cyanobacterium Anabaena sp. strain PCC 7120, the ATP-driven glycolipid efflux pump DevBCA-TolC has been shown to be crucial for the differentiation of N(2)-fixing heterocysts from photosynthetically active vegetative cells. In this study, a homologous system was described. All0809/8/7-TolC form a typical ATP-driven efflux pump as shown by surface plasmon resonance. This putative exporter is also involved in diazotrophic growth of Anabaena sp. PCC 7120. A mutant in all0809 encoding the periplasmic membrane fusion protein of the pump was not able to grow without combined nitrogen. Although heterocysts of this mutant were not distinguishable from those of the wild-type in light and electron micrographs, they were impaired in providing the microoxic environment necessary for N(2) fixation. RT-PCR of all0809 transcripts and localization studies on All0807-GFP revealed that All0809/8/7 was initially downregulated during heterocyst maturation and upregulated at later stages of heterocyst formation in all cells of the filament. A substrate of the efflux pump could not be identified in ATP hydrolysis assays. We discuss a role for All0809/8/7-TolC in maintaining the continuous periplasm and how this would be of special importance for heterocyst differentiation.

  12. Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast

    PubMed Central

    Huckaba, Thomas M.; Lipkin, Thomas; Pon, Liza A.

    2006-01-01

    Retrograde flow of cortical actin networks and bundles is essential for cell motility and retrograde intracellular movement, and for the formation and maintenance of microvilli, stereocilia, and filopodia. Actin cables, which are F-actin bundles that serve as tracks for anterograde and retrograde cargo movement in budding yeast, undergo retrograde flow that is driven, in part, by actin polymerization and assembly. We find that the actin cable retrograde flow rate is reduced by deletion or delocalization of the type II myosin Myo1p, and by deletion or conditional mutation of the Myo1p motor domain. Deletion of the tropomyosin isoform Tpm2p, but not the Tpm1p isoform, increases the rate of actin cable retrograde flow. Pretreatment of F-actin with Tpm2p, but not Tpm1p, inhibits Myo1p binding to F-actin and Myo1p-dependent F-actin gliding. These data support novel, opposing roles of Myo1p and Tpm2 in regulating retrograde actin flow in budding yeast and an isoform-specific function of Tpm1p in promoting actin cable function in myosin-driven anterograde cargo transport. PMID:17178912

  13. Stochastic driven systems far from equilibrium

    NASA Astrophysics Data System (ADS)

    Kim, Kyung Hyuk

    We study the dynamics and steady states of two systems far from equilibrium: a 1-D driven lattice gas and a driven Brownian particle with inertia. (1) We investigate the dynamical scaling behavior of a 1-D driven lattice gas model with two species of particles hopping in opposite directions. We confirm numerically that the dynamic exponent is equal to z = 1.5. We show analytically that a quasi-particle representation relates all phase points to a special phase line directly related to the single-species asymmetric simple exclusion process. Quasi-particle two-point correlations decay exponentially, and in such a manner that quasi-particles of opposite charge dynamically screen each other with a special balance. The balance encompasses all over the phase space. These results indicate that the model belongs to the Kardar-Parisi-Zhang (KPZ) universality class. (2) We investigate the non-equilibrium thermodynamics of a Brownian particle with inertia under feedback control of its inertia. We find such open systems can act as a molecular refrigerator due to an entropy pumping mechanism. We extend the fluctuation theorems to the refrigerator. The entropy pumping modifies both the Jarzynski equality and the fluctuation theorems. We discover that the entropy pumping has a dual role of work and heat. We also investigate the thermodynamics of the particle under a hydrodynamic interaction described by a Langevin equation with a multiplicative noise. The Stratonovich stochastic integration prescription involved in the definition of heat is shown to be the unique physical choice.

  14. Fire safety evaluation of aircraft lavatory and cargo compartments

    NASA Technical Reports Server (NTRS)

    Kourtides, D. A.; Parker, J. A.; Hilado, C. J.; Anderson, R. A.; Tustin, E.; Arnold, D. B.; Gaume, J. G.; Binding, A. T.; Mikeska, J. L.

    1976-01-01

    A program of experimental fires has been carried out to assess fire containment and other fire hazards in lavatory and cargo compartments of wide-body jet aircraft by evaluation of ignition time, burn-through time, fire spread rate, smoke density, evolution of selected combustible and toxic gases, heat flux, and detector response. Two tests were conducted: one involving a standard Boeing 747 lavatory and one involving a simulated DC-10 cargo compartment. A production lavatory module was furnished with conventional materials and was installed in an enclosure. The ignition load was four polyethylene bags containing paper and plastic waste materials representive of a maximum flight cabin waste load. Standard aircraft ventilation conditions were utilized and the lavatory door was closed during the test. Lavatory wall and ceiling panels contained the fire spread during the 30-minute test. Smoke was driven into the enclosure primarily through the ventilation grille in the door and through the gaps between the bifold door and the jamb where the door distorted from the heat earlier in the test. The interior of the lavatory was almost completely destroyed by the fire.

  15. Chemically generated convective transport in microfluidic system

    NASA Astrophysics Data System (ADS)

    Shklyaev, Oleg; Das, Sambeeta; Altemose, Alicia; Shum, Henry; Balazs, Anna; Sen, Ayusman

    High precision manipulation of small volumes of fluid, containing suspended micron sized objects like cells, viruses, and large molecules, is one of the main goals in designing modern lab-on-a-chip devices which can find a variety of chemical and biological applications. To transport the cargo toward sensing elements, typical microfluidic devices often use pressure driven flows. Here, we propose to use enzymatic chemical reactions which decompose reagent into less dense products and generate flows that can transport particles. Density variations that lead to flow in the assigned direction are created between the place where reagent is fed into the solution and the location where it is decomposed by enzymes attached to the surface of the microchannel. When the reagent is depleted, the fluid motion stops and particles sediment to the bottom. We demonstrate how the choice of chemicals, leading to specific reaction rates, can affect the transport properties. In particular, we show that the intensity of the fluid flow, the final location of cargo, and the time for cargo delivery are controlled by the amount and type of reagent in the system.

  16. Experimental study of operation performance for hydrocarbon fuel pump with low specific speed

    NASA Astrophysics Data System (ADS)

    Wu, Xianyu; Yang, Jun; Jin, Xuan

    2017-10-01

    In this paper, a small flow rate hydrocarbon turbine pump was used to pressurize the fuel supply system of scramjet engine. Some experiments were carried out to investigate the characteristics of turbine pump driven by nitrogen or combustion gas under different operating conditions. A experimental database with regard to the curves of the rotational speed, mass flow rate and net head with regard to centrifugal pump were plotted. These curves were represented as functions of the pressure and temperature at turbine inlet/outlet and the throttle diameter at downstream of centrifugal pump. A sensitivity study has been carried out based on design of experiments. The experimental was employed to analyze net head of centrifugal and throttle characteristics. The research results can accumulate foundations for the close loop control system of turbine pump.

  17. Distinct cargo-specific response landscapes underpin the complex and nuanced role of galectin-glycan interactions in clathrin-independent endocytosis.

    PubMed

    Mathew, Mohit P; Donaldson, Julie G

    2018-05-11

    Clathrin-independent endocytosis (CIE) is a form of endocytosis that lacks a defined cytoplasmic machinery. Here, we asked whether glycan interactions, acting from the outside, could be a part of that endocytic machinery. We show that the perturbation of global cellular patterns of protein glycosylation by modulation of metabolic flux affects CIE. Interestingly, these changes in glycosylation had cargo-specific effects. For example, in HeLa cells, GlcNAc treatment, which increases glycan branching, increased major histocompatibility complex class I (MHCI) internalization but inhibited CIE of the glycoprotein CD59 molecule (CD59). The effects of knocking down the expression of galectin 3, a carbohydrate-binding protein and an important player in galectin-glycan interactions, were also cargo-specific and stimulated CD59 uptake. By contrast, inhibition of all galectin-glycan interactions by lactose inhibited CIE of both MHCI and CD59. None of these treatments affected clathrin-mediated endocytosis, implying that glycosylation changes specifically affect CIE. We also found that the galectin lattice tailors membrane fluidity and cell spreading. Furthermore, changes in membrane dynamics mediated by the galectin lattice affected macropinocytosis, an altered form of CIE, in HT1080 cells. Our results suggest that glycans play an important and nuanced role in CIE, with each cargo being affected uniquely by alterations in galectin and glycan profiles and their interactions. We conclude that galectin-driven effects exist on a continuum from stimulatory to inhibitory, with distinct CIE cargo proteins having unique response landscapes and with different cell types starting at different positions on these conceptual landscapes.

  18. KSC-2009-2239

    NASA Image and Video Library

    2009-03-21

    CAPE CANAVERAL, Fla. – On the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida, a truck carrying the EXPRESS Logistics Carrier for the STS-129 mission drives out of the open rear of the C-17 cargo plane. The carrier is part of the payload on space shuttle Atlantis, which will deliver to the International Space Station components including two spare gyroscopes, two nitrogen tank assemblies, two pump modules, an ammonia tank assembly and a spare latching end effector for the station's robotic arm. STS-129 is targeted to launch Nov. 12. Photo credit: NASA/Tim Jacobs

  19. KSC-2009-2240

    NASA Image and Video Library

    2009-03-21

    CAPE CANAVERAL, Fla. – The truck carrying the EXPRESS Logistics Carrier for the STS-129 mission pulls away from the C-17 cargo plane that delivered it to NASA's Kennedy Space Center in Florida. The carrier is part of the payload on space shuttle Atlantis, which will deliver to the International Space Station components including two spare gyroscopes, two nitrogen tank assemblies, two pump modules, an ammonia tank assembly and a spare latching end effector for the station's robotic arm. STS-129 is targeted to launch Nov. 12. Photo credit: NASA/Tim Jacobs

  20. Possible roles of two quinone molecules in direct and indirect proton pumps of bovine heart NADH-quinone oxidoreductase (complex I).

    PubMed

    Ohnishi, S Tsuyoshi; Salerno, John C; Ohnishi, Tomoko

    2010-12-01

    In many energy transducing systems which couple electron and proton transport, for example, bacterial photosynthetic reaction center, cytochrome bc(1)-complex (complex III) and E. coli quinol oxidase (cytochrome bo(3) complex), two protein-associated quinone molecules are known to work together. T. Ohnishi and her collaborators reported that two distinct semiquinone species also play important roles in NADH-ubiquinone oxidoreductase (complex I). They were called SQ(Nf) (fast relaxing semiquinone) and SQ(Ns) (slow relaxing semiquinone). It was proposed that Q(Nf) serves as a "direct" proton carrier in the semiquinone-gated proton pump (Ohnishi and Salerno, FEBS Letters 579 (2005) 4555), while Q(Ns) works as a converter between one-electron and two-electron transport processes. This communication presents a revised hypothesis in which Q(Nf) plays a role in a "direct" redox-driven proton pump, while Q(Ns) triggers an "indirect" conformation-driven proton pump. Q(Nf) and Q(Ns) together serve as (1e(-)/2e(-)) converter, for the transfer of reducing equivalent to the Q-pool. Copyright © 2010 Elsevier B.V. All rights reserved.

  1. Non-Covalent Microgel Particles Containing Functional Payloads: Coacervation of PEG-Based Triblocks via Microfluidics.

    PubMed

    Wang, Cynthia X; Utech, Stefanie; Gopez, Jeffrey D; Mabesoone, Mathijs F J; Hawker, Craig J; Klinger, Daniel

    2016-07-06

    Well-defined microgel particles were prepared by combining coacervate-driven cross-linking of ionic triblock copolymers with the ability to control particle size and encapsulate functional cargos inherent in microfluidic devices. In this approach, the efficient assembly of PEO-based triblock copolymers with oppositely charged end-blocks allows for bioinspired cross-linking under mild conditions in dispersed aqueous droplets. This strategy enables the integration of charged cargos into the coacervate domains (e.g., the loading of anionic model compounds through electrostatic association with cationic end-blocks). Distinct release profiles can be realized by systematically varying the chemical nature of the payload and the microgel dimensions. This mild and noncovalent assembly method represents a promising new approach to tunable microgels as scaffolds for colloidal biomaterials in therapeutics and regenerative medicine.

  2. Controlling the light propagation in one-dimensional photonic crystal via incoherent pump and interdot tunneling

    NASA Astrophysics Data System (ADS)

    Abbasabadi, Majid; Sahrai, Mostafa

    2018-01-01

    We investigated the propagation of an electromagnetic pulse through a one-dimensional photonic crystal doped with quantum-dot (QD) molecules in a defect layer. The QD molecules behave as a three-level quantum system and are driven by a coherent probe laser field and an incoherent pump field. No coherent coupling laser fields were introduced, and the coherence was created by the interdot tunnel effect. Further studied was the effect of tunneling and incoherent pumping on the group velocity of the transmitted and reflected probe pulse.

  3. Flushing of a polluted lagoon in Canc'un, using a SIBEO wave-driven seawater pump

    NASA Astrophysics Data System (ADS)

    Czitrom, Steven; Carbajal, Noel

    2006-11-01

    The coastal lagoon which adorns the seaside resort at Canc'un, Mexico, is heavily polluted as a result of decades of intense tourist activity development and overwhelmed inadequate planning. The natural flushing time of the lagoon, estimated at 2 to 4 years, is insufficient to cope with the waste that is being dumped and a thick layer of organic matter has accumulated on the lagoon bed. Appropriate legal and sewage treatment measures are imperative to curb further dumping and thus attack the root cause of the problem. This aside, however, the existing situation requires additional technical solutions to restore the ecosystem to a less altered state. A wave and tide driven seawater pump, invented and developed at the National University of Mexico, has been proposed to flush the lagoon with an average 0.2 m^3/s of clean and oxygen rich seawater from the neighboring ocean. This flow would reduce the residence time of the lagoon to around 6 months, promoting long term recovery of the ecosystem. The effect and distribution of the pumped water is being studied using a wind and tide driven 3D numerical model of the lagoon hydrodynamics. Some results from this study are presented here.

  4. Dynamically balanced, hydraulically driven compressor/pump apparatus for resonant free piston Stirling engines

    DOEpatents

    Corey, John A.

    1984-05-29

    A compressor, pump, or alternator apparatus is designed for use with a resonant free piston Stirling engine so as to isolate apparatus fluid from the periodically pressurized working fluid of the Stirling engine. The apparatus housing has a first side closed by a power coupling flexible diaphragm (the engine working member) and a second side closed by a flexible diaphragm gas spring. A reciprocally movable piston is disposed in a transverse cylinder in the housing and moves substantially at right angles relative to the flexible diaphragms. An incompressible fluid fills the housing which is divided into two separate chambers by suitable ports. One chamber provides fluid coupling between the power diaphragm of the RFPSE and the piston and the second chamber provides fluid coupling between the gas spring diaphragm and the opposite side of the piston. The working members of a gas compressor, pump, or alternator are driven by the piston. Sealing and wearing parts of the apparatus are mounted at the external ends of the transverse cylinder in a double acting arrangement for accessibility. An annular counterweight is mounted externally of the reciprocally movable piston and is driven by incompressible fluid coupling in a direction opposite to the piston so as to damp out transverse vibrations.

  5. Custom Unit Pump Design and Testing for the EVA PLSS

    NASA Technical Reports Server (NTRS)

    Schuller, Michael; Kurwitz, Cable; Goldman, Jeff; Morris, Kim; Trevino, Luis

    2009-01-01

    This paper describes the effort by the Texas Engineering Experiment Station (TEES) and Honeywell for NASA to design and test a pre-flight prototype pump for use in the Extra-vehicular activity (EVA) portable life support subsystem (PLSS). Major design decisions were driven by the need to reduce the pump s mass, power, and volume compared to the existing PLSS pump. In addition, the pump must accommodate a much wider range of abnormal conditions than the existing pump, including vapor/gas bubbles and increased pressure drop when employed to cool two suits simultaneously. A positive displacement, external gear type pump was selected because it offers the most compact and highest efficiency solution over the required range of flow rates and pressure drops. An additional benefit of selecting a gear pump design is that it is self priming and capable of ingesting non-condensable gas without becoming air locked. The chosen pump design consists of a 28 V DC, brushless, sealless, permanent magnet motor driven, external gear pump that utilizes a Honeywell development that eliminates the need for magnetic coupling. Although the planned flight unit will use a sensorless motor with custom designed controller, the pre-flight prototype to be provided for this project incorporates Hall effect sensors, allowing an interface with a readily available commercial motor controller. This design approach reduced the cost of this project and gives NASA more flexibility in future PLSS laboratory testing. The pump design was based on existing Honeywell designs, but incorporated features specifically for the PLSS application, including all of the key features of the flight pump. Testing at TEES verified that the pump meets the design requirements for range of flow rates, pressure drop, power consumption, working fluid temperature, operating time, gas ingestion , and restart capability under both ambient and vacuum conditions. The pump operated between 40 and 240 lbm/hr flowrate, 35 to 100 F pump temperature range, and 5 to 10 psid pressure rise. Power consumption of the pump controller at the nominal operating point in both ambient and vacuum conditions was 9.5 W, which was less than the 12 W predicted. Gas ingestion capabilities were tested by injecting 100 cc of air into the fluid line; the pump operated normally throughout this test. The test results contained a number of anomalies, specifically power increases and a few flow stoppages, that prompted TEES and Honeywell to disassemble and inspect the pump. Inspection indicated contamination in the pump and fit issues may have played roles in the observed anomalies. Testing following reassembly indicated that the performance of the pump 1) matched both the predicted performance values, 2) the performance values measured prior to disassembly, and 3) was free of the anomalies noted in the pre-disassembly testing.

  6. Bose-Einstein condensation of spin wave quanta at room temperature.

    PubMed

    Dzyapko, O; Demidov, V E; Melkov, G A; Demokritov, S O

    2011-09-28

    Spin waves are delocalized excitations of magnetic media that mainly determine their magnetic dynamics and thermodynamics at temperatures far below the critical one. The quantum-mechanical counterparts of spin waves are magnons, which can be considered as a gas of weakly interacting bosonic quasi-particles. Here, we discuss the room-temperature kinetics and thermodynamics of the magnon gas in yttrium iron garnet films driven by parametric microwave pumping. We show that for high enough pumping powers, the thermalization of the driven gas results in a quasi-equilibrium state described by Bose-Einstein statistics with a non-zero chemical potential. Further increases of the pumping power cause a Bose-Einstein condensation documented by an observation of the magnon accumulation at the lowest energy level. Using the sensitivity of the Brillouin light scattering spectroscopy to the degree of coherence of the scattering magnons, we confirm the spontaneous emergence of coherence of the magnons accumulated at the bottom of the spectrum, occurring if their density exceeds a critical value.

  7. Cooling system for high speed aircraft

    NASA Technical Reports Server (NTRS)

    Lawing, P. L.; Pagel, L. L. (Inventor)

    1981-01-01

    The system eliminates the necessity of shielding an aircraft airframe constructed of material such as aluminum. Cooling is accomplished by passing a coolant through the aircraft airframe, the coolant acting as a carrier to remove heat from the airframe. The coolant is circulated through a heat pump and a heat exchanger which together extract essentially all of the added heat from the coolant. The heat is transferred to the aircraft fuel system via the heat exchanger and the heat pump. The heat extracted from the coolant is utilized to power the heat pump. The heat pump has associated therewith power turbine mechanism which is also driven by the extracted heat. The power turbines are utilized to drive various aircraft subsystems, the compressor of the heat pump, and provide engine cooling.

  8. The impact of the weather conditions on the cooling performance of the heat pump driven by an internal natural gas combustion engine

    NASA Astrophysics Data System (ADS)

    Janovcová, Martina; Jandačka, Jozef; Malcho, Milan

    2015-05-01

    Market with sources of heat and cold offers unlimited choice of different power these devices, design technology, efficiency and price categories. New progressive technologies are constantly discovering, about which is still little information, which include heat pumps powered by a combustion engine running on natural gas. A few pieces of these installations are in Slovakia, but no studies about their work and effectiveness under real conditions. This article deals with experimental measurements of gas heat pump efficiency in cooling mode. Since the gas heat pump works only in system air - water, air is the primary low - energy source, it is necessary to monitor the impact of the climate conditions for the gas heat pump performance.

  9. High-Pressure Open-Channel On-Chip Electroosmotic Pump for Nanoflow High Performance Liquid Chromatography

    PubMed Central

    2015-01-01

    Here, we construct an open-channel on-chip electroosmotic pump capable of generating pressures up to ∼170 bar and flow rates up to ∼500 nL/min, adequate for high performance liquid chromatographic (HPLC) separations. A great feature of this pump is that a number of its basic pump units can be connected in series to enhance its pumping power; the output pressure is directly proportional to the number of pump units connected. This additive nature is excellent and useful, and no other pumps can work in this fashion. We demonstrate the feasibility of using this pump to perform nanoflow HPLC separations; tryptic digests of bovine serum albumin (BSA), transferrin factor (TF), and human immunoglobulins (IgG) are utilized as exemplary samples. We also compare the performance of our electroosmotic (EO)-driven HPLC with Agilent 1200 HPLC; comparable efficiencies, resolutions, and peak capacities are obtained. Since the pump is based on electroosmosis, it has no moving parts. The common material and process also allow this pump to be integrated with other microfabricated functional components. Development of this high-pressure on-chip pump will have a profound impact on the advancement of lab-on-a-chip devices. PMID:24495233

  10. Development of a proof of concept low temperature 4He Superfluid Magnetic Pump

    NASA Astrophysics Data System (ADS)

    Jahromi, Amir E.; Miller, Franklin K.

    2017-03-01

    We describe the development and experimental results of a proof of concept Superfluid Magnetic Pump in this work. This novel low temperature, no moving part pump can replace the existing bellows-piston driven 4He or 3He-4He mixture compressor/circulators used in various sub Kelvin refrigeration systems such as dilution, Superfluid pulse tube, Stirling, or active magnetic regenerative refrigerators. Due to the superior thermal transport properties of sub-Lambda 4He this pump can also be used as a simple circulator to distribute cooling over large surface areas. Our pump was experimentally shown to produce a maximum flow rate of 440 mg/s (averaged over cycle), 665 mg/s (peak) and produced a maximum pressure difference of 2323 Pa using only the more common isotope of helium, 4He. This pump worked in an ;ideal; thermodynamic state: The experimental results matched with the theoretical values predicted by a computer model. Pump curves were developed to map the performance of this pump. This successful demonstration will enable this novel pump to be implemented in suitable sub Kelvin refrigeration systems.

  11. A seal-less centrifugal pump (Baylor Gyro Pump) for application to long-term circulatory support.

    PubMed

    Minato, N; Sakuma, I; Sasaki, T; Shiono, M; Ohara, Y; Takatani, S; Noon, G P; Nosé, Y

    1993-01-01

    We are developing a new centrifugal pump, the Baylor Gyro Centrifugal Pump (Gyro Pump), which can function for more than 2 weeks. The concept of the Gyro Pump is that a one-piece rotor-impeller with embedded permanent magnets, driven directly by a brushless direct current motor stator placed outside, rotates like a "gyroscope," and the rotor-impeller is supported by one pivot bearing at the bottom in accordance with the gyroscopic principle. This concept enables us to eliminate a driving shaft and a seal between the driving shaft and the blood chamber, which results in extending the life of the centrifugal pump. The blood passes through the space between the motor stator and the rotor to the impeller portion. In this preliminary phase, two pivot bearings were applied to support the rotor-impeller at the top and the bottom inside the blood chamber. Both pivot bearings showed less blood trauma and less thrombogenicity in in vitro and in vivo studies. The Gyro Pump is a promising second-generation centrifugal pump for long-term circulatory support in the near future.

  12. Fluoride-fiber-based side-pump coupler for high-power fiber lasers at 2.8  μm.

    PubMed

    Schäfer, C A; Uehara, H; Konishi, D; Hattori, S; Matsukuma, H; Murakami, M; Shimizu, S; Tokita, S

    2018-05-15

    A side-pump coupler made of fluoride fibers was fabricated and tested. The tested device had a coupling efficiency of 83% and was driven with an incident pump power of up to 83.5 W, demonstrating high-power operation. Stable laser output of 15 W at a wavelength of around 2.8 μm was achieved over 1 h when using an erbium-doped double-clad fiber as the active medium. To the best of our knowledge, this is the first time a fluoride-glass-fiber-based side-pump coupler has been developed. A test with two devices demonstrated further power scalability.

  13. National Dam Safety Program. Water Works Lake Dam (MO 10006), Grand - Chariton River Basin, Randolph County, Missouri. Phase I Inspection Report.

    DTIC Science & Technology

    1979-11-01

    Engineering Consultants, Inc. Hydraulics & Hydrology Kevin Blume Consoer, Townsend & Assoc., Ltd. Civil and Structural Oran Patrick City of Moberly, Missouri...structure. Photo 13. - View of the diesel powered pump. Photo 14. - View of the electric driven pump. -4 .... Waer 4ork- I’ n Photo lPhotn Wot cr w-.’)rks

  14. 25. Hot well, as seen from port side aft. Waste ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Hot well, as seen from port side aft. Waste water overflow pipe appears at left, behind which is bilge pump. At base of hot well on either side are reciprocating boiler feedwater pumps driven from hot well crosshead. (Labels were applied by HAER recording team and are not original to equipment.) - Steamboat TICONDEROGA, Shelburne Museum Route 7, Shelburne, Chittenden County, VT

  15. A model investigation of turbulence-driven pressure-pumping effects on the rate of diffusion of CO2, N2O, and CH4 through layered snowpacks

    Treesearch

    W. J. Massman; R. A. Sommerfeld; A. R. Mosier; K. F. Zeller; T.J . Hehn; S. G. Rochelle

    1997-01-01

    Pressure pumping at the Earth's surface is caused by short-period atmospheric turbulence, longer-period barometric changes, and quasi-static pressure fields induced by wind blowing across irregular topography. These naturally occurring atmospheric pressure variations induce periodic fluctuations in airflow through snowpacks, soils, and any other porous media at...

  16. StarTram: An Ultra Low Cost Launch System to Enable Large Scale Exploration of the Solar System

    NASA Astrophysics Data System (ADS)

    Powell, James; Maise, George; Paniagua, John

    2006-01-01

    StarTram is a new approach for low launch to space using Maglev technology. Spacecraft are magnetically levitated and accelerated without propellants to orbital speeds in an evacuated tunnel at ground level using only electrical energy. The cost of the electric energy for acceleration to 8 kilometers per second is only 60 cents per kilogram of payload. After reaching orbital speed, the StarTram spacecraft coast upwards inside an evacuated levitated launch tube to an altitude, of 10 kilometers or more, where they enter the low-pressure ambient atmosphere. The launch tube is magnetically levitated by the repulsive force between a set of high current superconducting cables on it and oppositely directed currents in a set of superconducting cables on the ground beneath. High strength Kevlar tethers anchor the launch tube against crosswinds and prevent it from moving laterally or vertically. A Magneto Hydro Dynamic (MHD) pump at the exit of the evacuated launch tube prevents air from entering the tube. Two StarTram systems are described, a high G (30G) system for cargo only launch and a moderate G (2.5 G) system for passenger/cargo spacecraft. StarTram's projected unit cost is $30 per kilogram of payload launched, including operating and amortization costs. A single StarTram facility could launch more than 100,000 tons of cargo per year and many thousands of passengers. StarTram would use existing superconductors and materials, together with Maglev technology similar to that now operating. The StarTram cargo launch system could be implemented by 2020 AD and the passenger system by 2030 AD.

  17. The dynamic ocean biological pump: Insights from a global compilation of particulate organic carbon, CaCO3, and opal concentration profiles from the mesopelagic

    NASA Astrophysics Data System (ADS)

    Lam, Phoebe J.; Doney, Scott C.; Bishop, James K. B.

    2011-09-01

    We have compiled a global data set of 62 open ocean profiles of particulate organic carbon (POC), CaCO3, and opal concentrations collected by large volume in situ filtration in the upper 1000 m over the last 30 years. We define concentration-based metrics for the strength (POC concentration at depth) and efficiency (attenuation of POC with depth in the mesopelagic) of the biological pump. We show that the strength and efficiency of the biological pump are dynamic and are characterized by a regime of constant and high transfer efficiency at low to moderate surface POC and a bloom regime where the height of the bloom is characterized by a weak deep biological pump and low transfer efficiency. The variability in POC attenuation length scale manifests in a clear decoupling between the strength of the shallow biological pump (e.g., POC at the export depth) and the strength of the deep biological pump (POC at 500 m). We suggest that the paradigm of diatom-driven export production is driven by a too restrictive perspective on upper mesopelagic dynamics. Indeed, our full mesopelagic analysis suggests that large, blooming diatoms have low transfer efficiency and thus may not export substantially to depth; rather, our analysis suggests that ecosystems characterized by smaller cells and moderately high %CaCO3 have a high mesopelagic transfer efficiency and can have higher POC concentrations in the deep mesopelagic even with relatively low surface or near-surface POC. This has negative implications for the carbon sequestration prospects of deliberate iron fertilization.

  18. Simulation of Solar Heat Pump Dryer Directly Driven by Photovoltaic Panels

    NASA Astrophysics Data System (ADS)

    Houhou, H.; Yuan, W.; Wang, G.

    2017-05-01

    This paper investigates a new type of solar heat pump dryer directly driven by photovoltaic panels. In order to design this system, a mathematical model has been established describing the whole drying process, including models of key components and phenomena of heat and mass transfer at the product layer and the air. The results of simulation at different drying air temperatures and velocities have been calculated and it indicate that the temperature of drying air is crucial external parameter compared to the velocity, with the increase of drying temperature from 45°C to 55°C, the product moisture content (Kg water/Kg dry product) decreased from 0.75 Kg/Kg to 0.3 Kg/Kg.

  19. Baylor Gyro Pump: a completely seal-less centrifugal pump aiming for long-term circulatory support.

    PubMed

    Ohara, Y; Sakuma, I; Makinouchi, K; Damm, G; Glueck, J; Mizuguchi, K; Naito, K; Tasai, K; Orime, Y; Takatani, S

    1993-07-01

    A seal-less centrifugal pump aiming for long-term circulatory support has been developed. In this model, shaft seals that cause thrombus formation and blood leakage were eliminated. A brushless direct current motor was incorporated as a driving unit, and pivot bearings were used to support the impeller. With reference to its motor-driven system, this pump was named the M-Gyro Pump. The first model (M1) yielded an index of hemolysis of 0.005 g/100 L using bovine blood and demonstrated satisfactory performance as a right heart assist for 2 days (4 L/min, 60 mm Hg, 1,800 rpm). The second model (M2) has been developed for left heart assist by employing a stronger motor. The pump capacity was improved to 6 L/min against 240 mm Hg at 1,800 rpm, but significant heat generation was observed. By optimization of motor efficiency, the M2 model can be improved to meet the requirements of a pump for left heart assist.

  20. Satellite Propellant Pump Research

    NASA Technical Reports Server (NTRS)

    Schneider, Steven J.; Veres, Joseph P.; Hah, Chunill; Nerone, Anthony L.; Cunningham, Cameron C.; Kraft, Thomas G.; Tavernelli, Paul F.; Fraser, Bryan

    2005-01-01

    NASA Glenn initiated a satellite propellant pump technology demonstration program. The goal was to demonstrate the technologies for a 60 percent efficient pump at 1 gpm flow rate and 500 psia pressure rise. The pump design and analysis used the in-house developed computer codes named PUMPA and HPUMP3D. The requirements lead to a 4-stage impeller type pump design with a tip diameter of 0.54 inches and a rotational speed of 57,000 rpm. Analyses indicated that flow cavitation was not a problem in the design. Since the flow was incompressible, the stages were identical. Only the 2-stage pump was designed, fabricated, assembled, and tested for demonstration. Water was selected as the surrogate fluid for hydrazine in this program. Complete mechanical design including stress and dynamic analyses were conducted. The pump was driven by an electric motor directly coupled to the impellers. Runs up to 57,000 rpm were conducted, where a pressure rise of 200 psia at a flow rate of 0.8 gpm was measured to validate the design effort.

  1. Dual-channel current valve in a three terminal zigzag graphene nanoribbon junction

    NASA Astrophysics Data System (ADS)

    Zhang, L.

    2017-02-01

    We theoretically propose a dual-channel current valve based on a three terminal zigzag graphene nanoribbon (ZGNR) junction driven by three asymmetric time-dependent pumping potentials. By means of the Keldysh Green’s function method, we show that two asymmetric charge currents can be pumped in the different left-right terminals of the device at a zero bias, which mainly stems from the single photon-assisted pumping approximation and the valley valve effect in a ZGNR p-n junction. The ON and OFF states of pumped charge currents are crucially dependent on the even-odd chain widths of the three electrodes, the pumping frequency, the lattice potential and the Fermi level. Two-tunneling spin valves are also considered to spatially separate and detect 100% polarized spin currents owing to the combined spin pump effect and the valley selective transport in a three terminal ZGNR ferromagnetic junction. Our investigations might be helpful to control the spatial and spin degrees of freedom of electrons in graphene pumping devices.

  2. Traffic Flow of Interacting Self-Driven Particles: Rails and Trails, Vehicles and Vesicles

    NASA Astrophysics Data System (ADS)

    Chowdhury, Debashish

    One common feature of a vehicle, an ant and a kinesin motor is that they all convert chemical energy, derived from fuel or food, into mechanical energy required for their forward movement; such objects have been modelled in recent years as self-driven particles. Cytoskeletal filaments, e.g., microtubules, form a rail network for intra-cellular transport of vesicular cargo by molecular motors like, for example, kinesins. Similarly, ants move along trails while vehicles move along lanes. Therefore, the traffic of vehicles and organisms as well as that of molecular motors can be modelled as systems of interacting self-driven particles; these are of current interest in non-equilibrium statistical mechanics. In this paper we point out the common features of these model systems and emphasize the crucial differences in their physical properties.

  3. Deposition of amorphous carbon nitride films on flexible substrates by reactive sputtering for applications in light-driven active devices

    NASA Astrophysics Data System (ADS)

    Aono, Masami; Harata, Tomo; Odawara, Taku; Asai, Shinnosuke; Orihara, Dai; Nogi, Masaya

    2018-01-01

    Amorphous carbon nitride (a-CN x ) thin films deposited by reactive sputtering have great potential for driving source applications of light-driven active devices. We demonstrate, for the first time, the photoinduced deformation of a-CN x deposited on flexible substrates, namely, poly(ethylene naphthalate) (PEN) films and transparent cellulose nanopaper. a-CN x films without delamination were obtained on both substrates. By decreasing the thickness of PEN films, the photoinduced deformation became extremely large. A light-driven pump was fabricated using a-CN x -coated PEN films, and then the pumping motion was observed up to 10 Hz. When a He-Ne laser traced the surface of a-CN x films deposited on the nanopaper, the sample moved to the opposite side of the laser spot. The motion involved repeated expansions and contractions similar to the motion of caterpillars occurring owing to the temporary photoinduced deformation of a-CN x films.

  4. Transient many-body instability in driven Dirac materials

    NASA Astrophysics Data System (ADS)

    Pertsova, Anna; Triola, Christopher; Balatsky, Alexander

    The defining feature of a Dirac material (DM) is the presence of nodes in the low-energy excitation spectrum leading to a strong energy dependence of the density of states (DOS). The vanishing of the DOS at the nodal point implies a very low effective coupling constant which leads to stability of the node against electron-electron interactions. Non-equilibrium or driven DM, in which the DOS and hence the effective coupling can be controlled by external drive, offer a new platform for investigating collective instabilities. In this work, we discuss the possibility of realizing transient collective states in driven DMs. Motivated by recent pump-probe experiments which demonstrate the existence of long-lived photo-excited states in DMs, we consider an example of a transient excitonic instability in an optically-pumped DM. We identify experimental signatures of the transient excitonic condensate and provide estimates of the critical temperatures and lifetimes of these states for few important examples of DMs, such as single-layer graphene and topological-insulator surfaces.

  5. Long pulse production from short pulses

    DOEpatents

    Toeppen, John S.

    1994-01-01

    A method of producing a long output pulse (SA) from a short pump pulse (P), using an elongated amplified fiber (11) having a doped core (12) that provides an amplifying medium for light of one color when driven into an excited state by light of a shorter wavelength and a surrounding cladding 13. A seed beam (S) of the longer wavelength is injected into the core (12) at one end of the fiber (11) and a pump pulse (P) of the shorter wavelength is injected into the cladding (13) at the other end of the fiber (11). The counter-propagating seed beam (S) and pump pulse (P) will produce an amplified output pulse (SA) having a time duration equal to twice the transit time of the pump pulse (P) through the fiber (11) plus the length of the pump pulse (P).

  6. Use and engineering of efflux pumps for the export of olefins in microbes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mukhopadhyay, Aindrila

    2016-07-14

    The scope of the project is to investigate efflux pump systems in engineered host microorganisms, such as E. coli, and develop a pump engineered to export a target compound. To initiate the project in coordination with other TOTAL driven projects, the first target compound to be studied was 1-hexene. However, we were investigating other chemicals as Styrene. The main goal of the project was to generate a set of optimized efflux pump systems for microorganisms (E. coli and Streptomyces or other host) engineered to contain biosynthetic pathways to export large titers of target compounds that are toxic (or accumulate andmore » push back biosynthesis) to the host cell. An optimized microbial host will utilize specific and efficient cell wall located pumps to extrude harmful target compounds and enable greater production of these compounds.« less

  7. Theoretical and experimental studies of a magnetically actuated valveless micropump

    NASA Astrophysics Data System (ADS)

    Ashouri, Majid; Behshad Shafii, Mohammad; Moosavi, Ali

    2017-01-01

    This paper presents the prototype design, fabrication, and characterization of a magnetically actuated micropump. The pump body consists of three nozzle/diffuser elements and two pumping chambers connected to the ends of a flat-wall pumping cylinder. A cylindrical permanent magnet placed inside the pumping cylinder acts as a piston which reciprocates by using an external magnetic actuator driven by a motor. The magnetic piston is covered by a ferrofluid to provide self-sealing capability. A prototype composed of three bonded layers of polymethyl-methacrylate (PMMA) has been fabricated. Water has been successfully pumped at pressures of up to 750 Pa and flow rates of up to 700 µl min-1 while working at the piston actuation frequency of 4 and 5 Hz, respectively. 3D numerical simulations are also carried out to study the performance of the pump. The best experimental and numerical volumetric efficiency of the pump are about 7 and 8%, respectively, at the piston speed of 0.03 m s-1. The contactless external actuation feature of the design enables integration of the pump with other PMMA-based microfluidic systems with low cost and disposability.

  8. Reaction pathways of photoexcited retinal in proteorhodopsin studied by pump-dump-probe spectroscopy.

    PubMed

    Rupenyan, Alisa; van Stokkum, Ivo H M; Arents, Jos C; van Grondelle, Rienk; Hellingwerf, Klaas J; Groot, Marie Louise

    2009-12-17

    Proteorhodopsin (pR) is a membrane-embedded proton pump from the microbial rhodopsin family. Light absorption by its retinal chromophore initiates a photocycle, driven by trans/cis isomerization on the femtosecond to picosecond time scales. Here, we report a study on the photoisomerization dynamics of the retinal chromophore of pR, using dispersed ultrafast pump-dump-probe spectroscopy. The application of a pump pulse initiates the photocycle, and with an appropriately tuned dump pulse applied at a time delay after the dump, the molecules in the initial stages of the photochemical process can be de-excited and driven back to the ground state. In this way, we were able to resolve an intermediate on the electronic ground state that represents chromophores that are unsuccessful in isomerization. In particular, the fractions of molecules that undergo slow isomerization (20 ps) have a high probability to enter this state rather than the isomerized K-state. On the ground state reaction surface, return to the stable ground state conformation via a structural or vibrational relaxation occurs in 2-3 ps. Inclusion of this intermediate in the kinetic scheme led to more consistent spectra of the retinal-excited state, and to a more accurate estimation of the quantum yield of isomerization (Phi = 0.4 at pH 6).

  9. Nafion-coating of the electrodes improves the flow-stability of the Ag/SiO2/Ag2O electroosmotic pump.

    PubMed

    Shin, Woonsup; Zhu, Enhua; Nagarale, Rajaram Krishna; Kim, Chang Hwan; Lee, Jong Myung; Shin, Samuel Jaeho; Heller, Adam

    2011-06-15

    When a current or a voltage is applied across the ceramic membrane of the nongassing Ag/Ag(2)O-SiO(2)-Ag/Ag(2)O pump, protons produced in the anodic reaction 2Ag(s) + H(2)O → Ag(2)O(s) + 2H(+) + 2e(-) are driven to the cathode, where they are consumed by the reaction Ag(2)O(s) + H(2)O + 2e(-) → 2Ag(s) + 2 OH(-). The flow of water is induced by momentum transfer from the electric field-driven proton-sheet at the surface of the ceramic membrane. About 10(4) water molecules flowed per reacted electron. Because dissolved ions decrease the field at the membrane surface, the flow decreases upon increasing the ionic strength. For this reason Ag(+) ions introduced through the anodic reaction and by dissolution of Ag(2)O decrease the flow. Their accumulation is reduced by applying Nafion-films to the electrodes. The 20 μL min(-1) flow rate of 6 mm i.d. pumps with Nafion coated electrodes operate daily for 5 min at 1 V for 1 month, for 70 h when the pump is pulsed for 30 s every 30 min, and for 2 h when operating continuously.

  10. Dync1h1 Mutation Causes Proprioceptive Sensory Neuron Loss and Impaired Retrograde Axonal Transport of Dorsal Root Ganglion Neurons.

    PubMed

    Zhao, Jing; Wang, Yi; Xu, Huan; Fu, Yuan; Qian, Ting; Bo, Deng; Lu, Yan-Xin; Xiong, Yi; Wan, Jun; Zhang, Xiang; Dong, Qiang; Chen, Xiang-Jun

    2016-07-01

    Sprawling (Swl) is a radiation-induced mutation which has been identified to have a nine base pair deletion in dynein heavy chain 1 (DYNC1H1: encoded by a single gene Dync1h1). This study is to investigate the phenotype and the underlying mechanism of the Dync1h1 mutant. To display the phenotype of Swl mutant mice, we examined the embryos of homozygous (Swl/Swl) and heterozygous (Swl/+) mice and their postnatal dorsal root ganglion (DRG) of surviving Swl/+ mice. The Swl/+ mice could survive for a normal life span, while Swl/Swl could only survive till embryonic (E) 8.5 days. Excessive apoptosis of Swl/+ DRG neurons was revealed during E11.5-E15.5 days, and the peak rate was at E13.5 days. In vitro study of mutated DRG neurons showed impaired retrograde transport of dynein-driven nerve growth factor (NGF). Mitochondria, another dynein-driven cargo, demonstrated much slower retrograde transport velocity in Swl/+ neurons than in wild-type (WT) neurons. Nevertheless, the Swl, Loa, and Cra mutations did not affect homodimerization of DYNC1H1. The Swl/Swl mutation of Dync1h1 gene led to embryonic mal-development and lethality, whereas the Swl/+ DRG neurons demonstrated deficient retrograde transport in dynein-driven cargos and excessive apoptosis during mid- to late-developmental stages. The underlying mechanism of the mutation may not be due to impaired homodimerization of DYNC1H1. © 2016 John Wiley & Sons Ltd.

  11. Engineered tug-of-war between kinesin and dynein controls direction of microtubule transport in vivo

    PubMed Central

    Rezaul, Karim; Gupta, Dipika; Semenova, Irina; Ikeda, Kazuho; Kraikivski, Pavel; Yu, Ji; Cowan, Ann; Zaliapin, Ilya; Rodionov, Vladimir

    2017-01-01

    Bidirectional transport of membrane organelles along microtubules (MTs) is driven by plus-end directed kinesins and minus-end directed dynein bound to the same cargo. Activities of opposing MT motors produce bidirectional movement of membrane organelles and cytoplasmic particles along MT transport tracks. Directionality of MT-based transport might be controlled by a protein complex that determines which motor type is active at any given moment of time, or determined by the outcome of a tug-of-war between MT motors dragging cargo organelles in opposite directions. However, evidence in support of each mechanisms of regulation is based mostly on the results of theoretical analyses or indirect experimental data. Here, we test whether the direction of movement of membrane organelles in vivo can be controlled by the tug-of-war between opposing MT motors alone, by attaching large number of kinesin-1 motors to organelles transported by dynein to minus-ends of MTs. We find that recruitment of kinesin significantly reduces the length and velocity of minus-end-directed dynein-dependent MT runs, leading to a reversal of the overall direction of dynein-driven organelles in vivo. Therefore in the absence of external regulators tug-of-war between opposing MT motors alone is sufficient to determine the directionality of MT transport in vivo. PMID:26843027

  12. Optical gain in an optically driven three-level ? system in atomic Rb vapor

    NASA Astrophysics Data System (ADS)

    Ballmann, C. W.; Yakovlev, V. V.

    2018-06-01

    In this work, we report experimentally achieved optical gain of a weak probe beam in a three-level ? system in a low density Rubidium vapor cell driven by a single pump beam. The maximum measured gain of the probe beam was about 0.12%. This work could lead to new approaches for enhancing molecular spectroscopy applications.

  13. Mimicking Nonequilibrium Steady States with Time-Periodic Driving

    NASA Astrophysics Data System (ADS)

    Raz, O.; Subaşı, Y.; Jarzynski, C.

    2016-04-01

    Under static conditions, a system satisfying detailed balance generically relaxes to an equilibrium state in which there are no currents. To generate persistent currents, either detailed balance must be broken or the system must be driven in a time-dependent manner. A stationary system that violates detailed balance evolves to a nonequilibrium steady state (NESS) characterized by fixed currents. Conversely, a system that satisfies instantaneous detailed balance but is driven by the time-periodic variation of external parameters—also known as a stochastic pump (SP)—reaches a periodic state with nonvanishing currents. In both cases, these currents are maintained at the cost of entropy production. Are these two paradigmatic scenarios effectively equivalent? For discrete-state systems, we establish a mapping between nonequilibrium stationary states and stochastic pumps. Given a NESS characterized by a particular set of stationary probabilities, currents, and entropy production rates, we show how to construct a SP with exactly the same (time-averaged) values. The mapping works in the opposite direction as well. These results establish a proof of principle: They show that stochastic pumps are able to mimic the behavior of nonequilibrium steady states, and vice versa, within the theoretical framework of discrete-state stochastic thermodynamics. Nonequilibrium steady states and stochastic pumps are often used to model, respectively, biomolecular motors driven by chemical reactions and artificial molecular machines steered by the variation of external, macroscopic parameters. Our results loosely suggest that anything a biomolecular machine can do, an artificial molecular machine can do equally well. We illustrate this principle by showing that kinetic proofreading, a NESS mechanism that explains the low error rates in biochemical reactions, can be effectively mimicked by a constrained periodic driving.

  14. Numerical Calculation and Experiment of Coupled Dynamics of the Differential Velocity Vane Pump Driven by the Hybrid Higher-order Fourier Non-circular Gears

    NASA Astrophysics Data System (ADS)

    Xu, Gaohuan; Chen, Jianneng; Zhao, Huacheng

    2018-06-01

    The transmission systems of the differential velocity vane pumps (DVVP) have periodic vibrations under loads. And it is not easy to find the reason. In order to optimize the performance of the pump, the authors proposed DVVP driven by the hybrid Higher-order Fourier non-circular gears and tested it. There were also similar periodic vibrations and noises under loads. Taking into account this phenomenon, the paper proposes fluid mechanics and solid mechanics simulation methodology to analyze the coupling dynamics between fluid and transmission system and reveals the reason. The results show that the pump has the reverse drive phenomenon, which is that the blades drive the non-circular gears when the suction and discharge is alternating. The reverse drive phenomenon leads the sign of the shaft torque to be changed in positive and negative way. So the transmission system produces torsional vibrations. In order to confirm the simulation results, micro strains of the input shaft of the pump impeller are measured by the Wheatstone bridge and wireless sensor technology. The relationships between strain and torque are obtained by experimental calibration, and then the true torque of input shaft is calculated indirectly. The experimental results are consistent to the simulation results. It is proven that the periodic vibrations are mainly caused by fluid solid coupling, which leads to periodic torsional vibration of the transmission system.

  15. Solar-powered Rankine heat pump for heating and cooling

    NASA Technical Reports Server (NTRS)

    Rousseau, J.

    1978-01-01

    The design, operation and performance of a familyy of solar heating and cooling systems are discussed. The systems feature a reversible heat pump operating with R-11 as the working fluid and using a motor-driven centrifugal compressor. In the cooling mode, solar energy provides the heat source for a Rankine power loop. The system is operational with heat source temperatures ranging from 155 to 220 F; the estimated coefficient of performance is 0.7. In the heating mode, the vapor-cycle heat pump processes solar energy collected at low temperatures (40 to 80 F). The speed of the compressor can be adjusted so that the heat pump capacity matches the load, allowing a seasonal coefficient of performance of about 8 to be attained.

  16. An accessible micro-capillary electrophoresis device using surface-tension-driven flow

    PubMed Central

    Mohanty, Swomitra K.; Warrick, Jay; Gorski, Jack; Beebe, David J.

    2010-01-01

    We present a rapidly fabricated micro-capillary electrophoresis chip that utilizes surface-tension-driven flow for sample injection and extraction of DNA. Surface-tension-driven flow (i.e. passive pumping) injects a fixed volume of sample that can be predicted mathematically. Passive pumping eliminates the need for tubing, valves, syringe pumps, and other equipment typically needed for interfacing with microelectrophoresis chips. This method requires a standard micropipette to load samples before separation, and remove the resulting bands after analysis. The device was made using liquid phase photopolymerization to rapidly fabricate the chip without the need of special equipment typically associated with the construction of microelectrophoresis chips (e.g. cleanroom). Batch fabrication time for the device presented here was 1.5 h including channel coating time to suppress electroosmotic flow. Devices were constructed out of poly-isobornyl acrylate and glass. A standard microscope with a UV source was used for sample detection. Separations were demonstrated using Promega BenchTop 100 bp ladder in hydroxyl ethyl cellulose (HEC) and oligonucleotides of 91 and 118 bp were used to characterize sample injection and extraction of DNA bands. The end result was an inexpensive micro-capillary electrophoresis device that uses tools (e.g. micropipette, electrophoretic power supplies, and microscopes) already present in most labs for sample manipulation and detection, making it more accessible for potential end users. PMID:19425002

  17. KSC-2009-2241

    NASA Image and Video Library

    2009-03-21

    CAPE CANAVERAL, Fla. – On the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida, a worker removes a cover from the EXPRESS Logistics Carrier for the STS-129 mission. The truck and carrier arrived on the C-17 cargo plane in the background. The carrier is part of the payload on space shuttle Atlantis, which will deliver to the International Space Station components including two spare gyroscopes, two nitrogen tank assemblies, two pump modules, an ammonia tank assembly and a spare latching end effector for the station's robotic arm. STS-129 is targeted to launch Nov. 12. Photo credit: NASA/Tim Jacobs

  18. Space shuttle safety - A hybrid vehicle breeds new problems.

    NASA Technical Reports Server (NTRS)

    Pinkel, I. I.

    1971-01-01

    Discussion of a few novel problems raised by the design and flight plan of the space shuttle and by the dangerous cargos it might carry. Among the problems cited are those connected with the inspection of the bearings of the propellant turbopumps, particularly those of the hydrogen pump, for evidence of spalling, as well as problems arising in the inspection of the high-temperature parts of the combustor and turbine section of the airbreathing turbofan for shuttle booster and orbiter, and problems resulting from the possibility of fire hazard due to spontaneous ignition of fuel vapor in the fuel tank vapor space.

  19. In vivo experimental testing of a microaxial blood pump for right ventricular support.

    PubMed

    Christiansen, Stefan; Perez-Bouza, Alberto; Reul, Helmut; Autschbach, Rüdiger

    2006-02-01

    The incidence of isolated right ventricular (RV) failure is rare in postcardiotomy patients, but high in patients undergoing implantation of a left ventricular assist device or cardiac transplantation. Therefore, we have developed a new microaxial flow device and report on our first in vivo animal trials. Six healthy adult female sheep weighing 80-90 kg underwent implantation of the microaxial blood pump for partial unloading of the right ventricle. This pump is a miniaturized rotary blood pump with a diameter of only 6.4 mm and a weight of 11 g. The inner volume of the pump is limited to 12 mL, and the inner artificial blood contacting surface is 65 cm(2). The pump consists of a rotor driven by an incorporated brushless direct current motor, the housing of the rotor, the inflow cage, the outflow cannula, and the driveline. At the maximum speed of 32,500 rotations/min, a flow of 6 L/min can be delivered. The inflow and outflow conduit were anastomosed to the right atrium and the main pulmonary artery, respectively. Hemodynamic and echocardiographic data as well as blood samples were measured over the whole test period of 7 days. The hearts and lungs as well as the pump were explanted for a thorough examination at the end of the trial. Systemic arterial blood pressures remained unchanged during the entire test period. RV cardiac output was diminished significantly as demonstrated by the echocardiographic studies. The number of platelets decreased perioperatively, but recovered within the test period. The free hemoglobin was not enhanced postoperatively indicating no significant hemolysis. Liver function was only slightly impaired due to operative reasons (increase in bilirubin on the first postoperative day but normalization within the test period). The pathologic examination revealed some clots at the inflow cage and fibrin depositions on the impeller as well as on the inner surface of the outflow graft without an impairment of pump function. Our results demonstrate that this newly developed microaxial blood pump is a promising device for RV support, but it cannot be driven without any anticoagulation.

  20. Mechanistic Insights from Structural Analyses of Ran-GTPase-Driven Nuclear Export of Proteins and RNAs.

    PubMed

    Matsuura, Yoshiyuki

    2016-05-22

    Understanding how macromolecules are rapidly exchanged between the nucleus and the cytoplasm through nuclear pore complexes is a fundamental problem in biology. Exportins are Ran-GTPase-dependent nuclear transport factors that belong to the karyopherin-β family and mediate nuclear export of a plethora of proteins and RNAs, except for bulk mRNA nuclear export. Exportins bind cargo macromolecules in a Ran-GTP-dependent manner in the nucleus, forming exportin-cargo-Ran-GTP complexes (nuclear export complexes). Transient weak interactions between exportins and nucleoporins containing characteristic FG (phenylalanine-glycine) repeat motifs facilitate nuclear pore complex passage of nuclear export complexes. In the cytoplasm, nuclear export complexes are disassembled, thereby releasing the cargo. GTP hydrolysis by Ran promoted in the cytoplasm makes the disassembly reaction virtually irreversible and provides thermodynamic driving force for the overall export reaction. In the past decade, X-ray crystallography of some of the exportins in various functional states coupled with functional analyses, single-particle electron microscopy, molecular dynamics simulations, and small-angle solution X-ray scattering has provided rich insights into the mechanism of cargo binding and release and also begins to elucidate how exportins interact with the FG repeat motifs. The knowledge gained from structural analyses of nuclear export is being translated into development of clinically useful inhibitors of nuclear export to treat human diseases such as cancer and influenza. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Properties of the anion-binding site of pharaonis Halorhodopsin studied by ultrafast pump-probe spectroscopy and low-temperature FTIR spectroscopy.

    PubMed

    Nakashima, Keisuke; Nakamura, Takumi; Takeuchi, Satoshi; Shibata, Mikihiro; Demura, Makoto; Tahara, Tahei; Kandori, Hideki

    2009-06-18

    Halorhodopsin (HR) is a light-driven chloride pump. Cl(-) is bound in the Schiff base region of the retinal chromophore, and unidirectional Cl(-) transport is probably enforced by the specific hydrogen-bonding interaction with the protonated Schiff base and internal water molecules. It is known that HR from Natronobacterium pharaonis (pHR) also pumps NO(3)(-) with similar efficiency, suggesting that NO(3)(-) binds to the Cl(-)-binding site. In the present study, we investigated the properties of the anion-binding site by means of ultrafast pump-probe spectroscopy and low-temperature FTIR spectroscopy. The obtained data were surprisingly similar between pHR-NO(3)(-) and pHR-Cl(-), even though the shapes and sizes of the two anions are quite different. Femtosecond pump-probe spectroscopy showed very similar excited-state dynamics between pHR-NO(3)(-) and pHR-Cl(-). Low-temperature FTIR spectroscopy of unlabeled and [zeta-(15)N]Lys-labeled pHR revealed almost identical hydrogen-bonding strengths of the protonated retinal Schiff base between pHR-NO(3)(-) and pHR-Cl(-), which is similarly strengthened after retinal isomerization. There were spectral variations for water stretching vibrations between pHR-NO(3)(-) and pHR-Cl(-), suggesting that the water molecules hydrate each anion. Nevertheless, the overall spectral features were similar for the two species. These observations strongly suggest that the anion-binding site has a flexible structure and that the interaction between retinal and the anions is weak, despite the presence of an electrostatic interaction. Such a flexible hydrogen-bonding network in the Schiff base region in HR appears to be in remarkable contrast to that in light-driven proton-pumping proteins.

  2. Enhanced mixing in polyacrylamide gels containing embedded silica nanoparticles as internal electroosmotic pumps.

    PubMed

    Matos, Marvi A; White, Lee R; Tilton, Robert D

    2008-02-15

    Many biosensors, including those based on sensing agents immobilized inside hydrogels, suffer from slow response dynamics due to mass transfer limitations. Here we present an internal pumping strategy to promote convective mixing inside crosslinked polymer gels. This is envisioned as a potential tool to enhance biosensor response dynamics. The method is based on electroosmotic flows driven by non-uniform, oscillating electric fields applied across a polyacrylamide gel that has been doped with charged colloidal silica inclusions. Evidence for enhanced mixing was obtained from florescence recovery after photobleaching (FRAP) measurements with fluorescein tracer dyes dissolved in the gel. Mixing rates in silica-laden gels under the action of the applied electric fields were more than an order of magnitude faster than either diffusion or electrophoretically driven mixing in gels that did not contain silica. The mixing enhancement was due in comparable parts to the electroosmotic pumping and to the increase in gel swelling caused by the presence of the silica inclusions. The latter had the effect of increasing tracer mobility in the silica-laden gels.

  3. SS Edgar M. Queeny collision with the Liberian S/T Corinthos, Marcus Hook, Pennsylvania, 31 January 1975. Marine casualty report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1977-10-27

    At 0029, on January 31, 1975, the U.S. Registered tankship SS EDGAR M. QUEENY, laden with chemical and petroleum products, was maneuvering into Marcus Hook channel of the Delaware River in Pennsylvania, when it collided with the Liberian tanker S/T CORINTHOS which was moored and discharging a bulk cargo of crude oil at the British Petroleum Company dock. The port anchor of the QUEENY slightly penetrated the port side plating of the CORINTHOS at an angle of about 39 deg. into one or more of the wing cargo tanks, which were being pumped and were approximately half full. Almost immediately,more » a series of increasingly intense explosions began in the CORINTHOS, and the vessel was engulfed in flames. Twenty-six persons were killed or are missing and 11 were injured in this accident. The QUEENY suffered minor damage but the CORINTHOS was destroyed. The Delaware River was polluted by oil about Marcus Hook. Property damage was estimated to be $20 million.« less

  4. Low-thrust chemical propulsion system pump technology

    NASA Technical Reports Server (NTRS)

    Meadville, J. W.

    1980-01-01

    A study was conducted within the thrust range 450 to 9000 N (100 to 2000 pounds). Performance analyses were made on centrifugal, pitot, Barske, drag, Tesla, gear, piston, lobe, and vane pumps with liquid hydrogen, liquid methane, and liquid oxygen as propellants. Gaseous methane and hydrogen driven axial impulse turbines, vane expanders, piston expanders, and electric motors were studied as drivers. Data are presented on performance, sizes, weights, and estimated service lives and costs.

  5. Jet pump assisted arterial heat pipe

    NASA Technical Reports Server (NTRS)

    Bienert, W. B.; Ducao, A. S.; Trimmer, D. S.

    1978-01-01

    This paper discusses the concept of an arterial heat pipe with a capillary driven jet pump. The jet pump generates a suction which pumps vapor and noncondensible gas from the artery. The suction also forces liquid into the artery and maintains it in a primed condition. A theoretical model was developed which predicts the existence of two stable ranges. Up to a certain tilt the artery will prime by itself once a heat load is applied to the heat pipe. At higher tilts, the jet pump can maintain the artery in a primed condition but self-priming is not possible. A prototype heat pipe was tested which self-primed up to a tilt of 1.9 cm, with a heat load of 500 watts. The heat pipe continued to prime reliably when operated as a VCHP, i.e., after a large amount of noncondensible gas was introduced.

  6. Development of a jet pump-assisted arterial heat pipe

    NASA Technical Reports Server (NTRS)

    Bienert, W. B.; Ducao, A. S.; Trimmer, D. S.

    1977-01-01

    The development of a jet pump assisted arterial heat pipe is described. The concept utilizes a built-in capillary driven jet pump to remove vapor and gas from the artery and to prime it. The continuous pumping action also prevents depriming during operation of the heat pipe. The concept is applicable to fixed conductance and gas loaded variable conductance heat pipes. A theoretical model for the jet pump assisted arterial heat pipe is presented. The model was used to design a prototype for laboratory demonstration. The 1.2 m long heat pipe was designed to transport 500 watts and to prime at an adverse elevation of up to 1.3 cm. The test results were in good agreement with the theoretical predictions. The heat pipe carried as much as 540 watts and was able to prime up to 1.9 cm. Introduction of a considerable amount of noncondensible gas had no adverse effect on the priming capability.

  7. Remotely powered distributed microfluidic pumps and mixers based on miniature diodes.

    PubMed

    Chang, Suk Tai; Beaumont, Erin; Petsev, Dimiter N; Velev, Orlin D

    2008-01-01

    We demonstrate new principles of microfluidic pumping and mixing by electronic components integrated into a microfluidic chip. The miniature diodes embedded into the microchannel walls rectify the voltage induced between their electrodes from an external alternating electric field. The resulting electroosmotic flows, developed in the vicinity of the diode surfaces, were utilized for pumping or mixing of the fluid in the microfluidic channel. The flow velocity of liquid pumped by the diodes facing in the same direction linearly increased with the magnitude of the applied voltage and the pumping direction could be controlled by the pH of the solutions. The transverse flow driven by the localized electroosmotic flux between diodes oriented oppositely on the microchannel was used in microfluidic mixers. The experimental results were interpreted by numerical simulations of the electrohydrodynamic flows. The techniques may be used in novel actively controlled microfluidic-electronic chips.

  8. SSME structural dynamic model development

    NASA Technical Reports Server (NTRS)

    Foley, Michael J.

    1989-01-01

    The high pressure fuel turbopump (HPFTP) is a major component of the Space Shuttle Main Engine (SSME) powerhead. The device is a three stage centrifugal pump that is directly driven by a two stage hot gas turbine. The purpose of the pump is to deliver fuel (liquid hydrogen) from the low pressure fuel turbopump (LPFTP) through the main fuel valve (MFV) to the thrust chamber coolant circuits. In doing so, the pump pressurizes the fuel from an inlet pressure of approximately 178 psi to a discharge pressure of over 6000 psi. At full power level (FPL), the pump rotates at a speed of over 37,000 rpm while generating approximately 77,000 horsepower. Obviously, a pump failure at these speeds and power levels could jeopardize the mission. Results are summarized for work in which the solutions obtained from analytical models of the fuel turbopump impellers are compared with the results obtained from dynamic tests.

  9. Refrigerant charge management in a heat pump water heater

    DOEpatents

    Chen, Jie; Hampton, Justin W.

    2014-06-24

    Heat pumps that heat or cool a space and that also heat water, refrigerant management systems for such heat pumps, methods of managing refrigerant charge, and methods for heating and cooling a space and heating water. Various embodiments deliver refrigerant gas to a heat exchanger that is not needed for transferring heat, drive liquid refrigerant out of that heat exchanger, isolate that heat exchanger against additional refrigerant flowing into it, and operate the heat pump while the heat exchanger is isolated. The heat exchanger can be isolated by closing an electronic expansion valve, actuating a refrigerant management valve, or both. Refrigerant charge can be controlled or adjusted by controlling how much liquid refrigerant is driven from the heat exchanger, by letting refrigerant back into the heat exchanger, or both. Heat pumps can be operated in different modes of operation, and segments of refrigerant conduit can be interconnected with various components.

  10. Sizing and modelling of photovoltaic water pumping system

    NASA Astrophysics Data System (ADS)

    Al-Badi, A.; Yousef, H.; Al Mahmoudi, T.; Al-Shammaki, M.; Al-Abri, A.; Al-Hinai, A.

    2018-05-01

    With the decline in price of the photovoltaics (PVs) their use as a power source for water pumping is the most attractive solution instead of using diesel generators or electric motors driven by a grid system. In this paper, a method to design a PV pumping system is presented and discussed, which is then used to calculate the required size of the PV for an existing farm. Furthermore, the amount of carbon dioxide emissions saved by the use of PV water pumping system instead of using diesel-fuelled generators or electrical motor connected to the grid network is calculated. In addition, an experimental set-up is developed for the PV water pumping system using both DC and AC motors with batteries. The experimental tests are used to validate the developed MATLAB model. This research work demonstrates that using the PV water pumping system is not only improving the living conditions in rural areas but it is also protecting the environment and can be a cost-effective application in remote locations.

  11. Carbon fluxes in the Arabian Sea: Export versus recycling

    NASA Astrophysics Data System (ADS)

    Rixen, Tim; Gaye, Birgit; Ramaswamy, Venkitasubramani

    2016-04-01

    The organic carbon pump strongly influences the exchange of carbon between the ocean and the atmosphere. It is known that it responds to global change but the magnitude and the direction of change are still unpredictable. Sediment trap experiments carried out at various sites in the Arabian Sea between 1986 and 1998 have shown differences in the functioning of the organic carbon pump (OCP). An OCP driven by eukaryotic phytoplankton operated in the upwelling region off Oman and during the spring bloom in the northern Arabian Sea. Cyanobacteria capable of fixing nitrogen seem to dominate the phytoplankton community during all other seasons. The export driven by cyanobacteria was much lower than the export driven by eukaryotic phytoplankton. Productivity and nutrient availability seems to be a main factor controlling fluxes during blooms of eukaryotic phytoplankton. The ballast effect caused by inputs of dust into the ocean and its incorporation into sinking particles seems to be the main factor controlling the export during times when cyanobacteria dominate the phytoplankton community. C/N ratios of organic matter exported from blooms dominated by nitrogen fixing cyanobacteria are enhanced and, furthermore, indicate a more efficient recycling of nutrients at shallower water depth. This implies that the bacterial-driven OCP operates more in a recycling mode that keeps nutrients closer to the euphotic zone whereas the OCP driven by eukaryotic phytoplankton reduces the recycling of nutrients by exporting them into greater water-depth.

  12. A compact centrifugal blood pump for extracorporeal circulation: design and performance.

    PubMed

    Tanaka, S; Yamamoto, S; Yamakoshi, K; Kamiya, A

    1987-08-01

    A new compact centrifugal blood pump driven by a miniature DC servomotor has been designed for use for short-term extra corporeal and cardiac-assisted circulation. The impeller of the pump was connected directly to the motor by using a simple-gear coupling. The shaft for the impeller was sealed from blood by both a V-ring and a seal bearing. Either pulsatile or nonpusatile flow was produced by controlling the current supply to the motor. The pump characteristics and the degree of hemolysis were evaluated with regard to the configuration of the impeller with a 38-mm outer diameter in vitro tests; the impeller having the blade angles at the inlet of 20 deg and at the outlet of 50 deg was the most appropriate as a blood pump. The performance in an operation, hemolysis and thrombus formation in the pump were assessed by a left ventricular bypass experiment in dogs. It was suggested by this study that this prototype pump appears promising for use not only in animal experiments but also in clinical application.

  13. STDCE, Payload Specialist Fred Leslie works at the STDCE rack in USML-2 Spacelab

    NASA Image and Video Library

    1995-11-05

    STS073-103-015 (20 October-5 November 1995) --- Payload specialist Fred W. Leslie works with the Surface Tension Driven Convection Experiment (STDCE) aboard the science module in the cargo bay of the Earth-orbiting Space Shuttle Columbia. Leslie joined another guest researcher and five NASA astronauts for 16 full days of in-space research in support of the United States Microgravity Laboratory (USML-2) mission.

  14. Navigating the plant cell: intracellular transport logistics in the green kingdom.

    PubMed

    Geitmann, Anja; Nebenführ, Andreas

    2015-10-01

    Intracellular transport in plant cells occurs on microtubular and actin arrays. Cytoplasmic streaming, the rapid motion of plant cell organelles, is mostly driven by an actin-myosin mechanism, whereas specialized functions, such as the transport of large cargo or the assembly of a new cell wall during cell division, are performed by the microtubules. Different modes of transport are used, fast and slow, to either haul cargo over long distances or ascertain high-precision targeting, respectively. Various forms of the actin-specific motor protein myosin XI exist in plant cells and might be involved in different cellular functions. © 2015 Geitmann and Nebenführ. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  15. On the Mysterious Propulsion of Synechococcus

    PubMed Central

    Ehlers, Kurt; Oster, George

    2012-01-01

    We propose a model for the self-propulsion of the marine bacterium Synechococcus utilizing a continuous looped helical track analogous to that found in Myxobacteria [1]. In our model cargo-carrying protein motors, driven by proton-motive force, move along a continuous looped helical track. The movement of the cargo creates surface distortions in the form of small amplitude traveling ridges along the S-layer above the helical track. The resulting fluid motion adjacent to the helical ribbon provides the propulsive thrust. A variation on the helical rotor model of [1] allows the motors to be anchored to the peptidoglycan layer, where they drive rotation of the track creating traveling helical waves along the S-layer. We derive expressions relating the swimming speed to the amplitude, wavelength, and velocity of the surface waves induced by the helical rotor, and show that they fall in reasonable ranges to explain the velocity and rotation rate of swimming Synechococcus. PMID:22567124

  16. Liposome-Cross-Linked Hybrid Hydrogels for Glutathione-Triggered Delivery of Multiple Cargo Molecules.

    PubMed

    Liang, Yingkai; Kiick, Kristi L

    2016-02-08

    Novel, liposome-cross-linked hybrid hydrogels cross-linked by the Michael-type addition of thiols with maleimides were prepared via the use of maleimide-functionalized liposome cross-linkers and thiolated polyethylene glycol (PEG) polymers. Gelation of the materials was confirmed by oscillatory rheology experiments. These hybrid hydrogels are rendered degradable upon exposure to thiol-containing molecules such as glutathione (GSH), via the incorporation of selected thioether succinimide cross-links between the PEG polymers and liposome nanoparticles. Dynamic light scattering (DLS) characterization confirmed that intact liposomes were released upon network degradation. Owing to the hierarchical structure of the network, multiple cargo molecules relevant for chemotherapies, namely doxorubicin (DOX) and cytochrome c, were encapsulated and simultaneously released from the hybrid hydrogels, with differential release profiles that were driven by degradation-mediated release and Fickian diffusion, respectively. This work introduces a facile approach for the development of advanced, hybrid drug delivery vehicles that exhibit novel chemical degradation.

  17. Thermal-Error Regime in High-Accuracy Gigahertz Single-Electron Pumping

    NASA Astrophysics Data System (ADS)

    Zhao, R.; Rossi, A.; Giblin, S. P.; Fletcher, J. D.; Hudson, F. E.; Möttönen, M.; Kataoka, M.; Dzurak, A. S.

    2017-10-01

    Single-electron pumps based on semiconductor quantum dots are promising candidates for the emerging quantum standard of electrical current. They can transfer discrete charges with part-per-million (ppm) precision in nanosecond time scales. Here, we employ a metal-oxide-semiconductor silicon quantum dot to experimentally demonstrate high-accuracy gigahertz single-electron pumping in the regime where the number of electrons trapped in the dot is determined by the thermal distribution in the reservoir leads. In a measurement with traceability to primary voltage and resistance standards, the averaged pump current over the quantized plateau, driven by a 1-GHz sinusoidal wave in the absence of a magnetic field, is equal to the ideal value of e f within a measurement uncertainty as low as 0.27 ppm.

  18. Kinking and Torsion Can Significantly Improve the Efficiency of Valveless Pumping in Periodically Compressed Tubular Conduits. Implications for Understanding of the Form-Function Relationship of Embryonic Heart Tubes.

    PubMed

    Hiermeier, Florian; Männer, Jörg

    2017-11-19

    Valveless pumping phenomena (peristalsis, Liebau-effect) can generate unidirectional fluid flow in periodically compressed tubular conduits. Early embryonic hearts are tubular conduits acting as valveless pumps. It is unclear whether such hearts work as peristaltic or Liebau-effect pumps. During the initial phase of its pumping activity, the originally straight embryonic heart is subjected to deforming forces that produce bending, twisting, kinking, and coiling. This deformation process is called cardiac looping. Its function is traditionally seen as generating a configuration needed for establishment of correct alignments of pulmonary and systemic flow pathways in the mature heart of lung-breathing vertebrates. This idea conflicts with the fact that cardiac looping occurs in all vertebrates, including gill-breathing fishes. We speculate that looping morphogenesis may improve the efficiency of valveless pumping. To test the physical plausibility of this hypothesis, we analyzed the pumping performance of a Liebau-effect pump in straight and looped (kinked) configurations. Compared to the straight configuration, the looped configuration significantly improved the pumping performance of our pump. This shows that looping can improve the efficiency of valveless pumping driven by the Liebau-effect. Further studies are needed to clarify whether this finding may have implications for understanding of the form-function relationship of embryonic hearts.

  19. Demand thrust pumped propulsion with automatic warm gas valving

    NASA Astrophysics Data System (ADS)

    Whitehead, J. C.

    1992-06-01

    Operation of a thrust-on-demand, monopropellant rocket propulsion system which uses lightweight low-pressure tankage, free-piston pumps, and a small high-pressure thrust chamber, is explained. The pump intake-exhaust valves use warm gas pneumatic signals to ensure that two reciprocating pumps are alternately pressurized, with overlap during switchover to permit uninterrupted propellant flow. Experiments demonstrate that the miniature pumps operate at any speed depending on downstream demand, and can deliver nearly their own mass in hydrazine per second, at 7 MPa (1000 psi). The valves, which use the alternating layers of metal and graphite to mitigate the effects of differential thermal expansion, have been warm-gas tested for thousands of cycles. For biopropellant operation, a pair of reciprocating oxidizer pumps would be slaved to the fuel pumps' pneumatic oscillator, to provide for pulsed or continuous demand-driven flow of both liquids. Mass ratios and thrust-to-weight ratios of demand-thrust pumped propulsion systems compare quite favorably to those of pressure-fed and turbo-pumped systems. Due to the relatively high densities of storable propellants, liquid mass fractions greater than 0.95 are attainable with these novel pumps, with thrust/weight ratios above 10. The high performance potential of small propulsion systems which use reciprocating pumps suggests that this technology can significantly increase the capability of many types of small spacecraft.

  20. Kinking and Torsion Can Significantly Improve the Efficiency of Valveless Pumping in Periodically Compressed Tubular Conduits. Implications for Understanding of the Form-Function Relationship of Embryonic Heart Tubes

    PubMed Central

    Hiermeier, Florian; Männer, Jörg

    2017-01-01

    Valveless pumping phenomena (peristalsis, Liebau-effect) can generate unidirectional fluid flow in periodically compressed tubular conduits. Early embryonic hearts are tubular conduits acting as valveless pumps. It is unclear whether such hearts work as peristaltic or Liebau-effect pumps. During the initial phase of its pumping activity, the originally straight embryonic heart is subjected to deforming forces that produce bending, twisting, kinking, and coiling. This deformation process is called cardiac looping. Its function is traditionally seen as generating a configuration needed for establishment of correct alignments of pulmonary and systemic flow pathways in the mature heart of lung-breathing vertebrates. This idea conflicts with the fact that cardiac looping occurs in all vertebrates, including gill-breathing fishes. We speculate that looping morphogenesis may improve the efficiency of valveless pumping. To test the physical plausibility of this hypothesis, we analyzed the pumping performance of a Liebau-effect pump in straight and looped (kinked) configurations. Compared to the straight configuration, the looped configuration significantly improved the pumping performance of our pump. This shows that looping can improve the efficiency of valveless pumping driven by the Liebau-effect. Further studies are needed to clarify whether this finding may have implications for understanding of the form-function relationship of embryonic hearts. PMID:29367548

  1. Lifelike Vascular Reperfusion of a Thiel-Embalmed Pig Model and Evaluation as a Surgical Training Tool.

    PubMed

    Willaert, Wouter; Tozzi, Francesca; Van Hoof, Tom; Ceelen, Wim; Pattyn, Piet; D''Herde, Katharina

    2016-01-01

    Vascular reperfusion of Thiel cadavers can aid surgical and anatomical instruction. This study investigated whether ideal embalming circumstances provide lifelike vascular flow, enabling surgical practice and enhancing anatomical reality. Pressure-controlled pump-driven administration of blue embalming solution was assessed directly postmortem in a pig model (n = 4). Investigation of subsequent pump-driven vascular injection of red paraffinum perliquidum (PP) included assessment of flow parameters, intracorporeal distribution, anatomical alterations, and feasibility for surgical training. The microscopic distribution of PP was analyzed in pump-embalmed pig and gravity-embalmed human small intestines. Embalming lasted 50-105 min, and maximum arterial pressure was 65 mm Hg. During embalming, the following consecutive alterations were observed: arterial filling, organ coloration, venous perfusion, and further tissue coloration during the next weeks. Most organs were adequately preserved. PP generated low arterial pressures (<30 mm Hg) and drained through the venous cannula. Generally, realistic reperfusion and preservation of original anatomy were observed, but leakage in the pleural, abdominal, and retroperitoneal cavities occurred, and computed tomography showed edematous spleen and liver. Reduction of arterial flow rates after venous drainage is a prerequisite to prevent anatomical deformation, allowing simulation of various surgeries. In pump-embalmed pig small intestines, PP flowed from artery to vein through the capillaries without extravasation. In contrast, arterioles were blocked in gravity-embalmed human tissues. In a pig model, immediate postmortem pressure-controlled pump embalming generates ideal circumstances for (micro)vascular reperfusion with PP, permitting lifelike anatomy instruction and surgical training. © 2016 S. Karger AG, Basel.

  2. Voltage-Driven Magnetization Switching and Spin Pumping in Weyl Semimetals

    NASA Astrophysics Data System (ADS)

    Kurebayashi, Daichi; Nomura, Kentaro

    2016-10-01

    We demonstrate electrical magnetization switching and spin pumping in magnetically doped Weyl semimetals. The Weyl semimetal is a three-dimensional gapless topological material, known to have nontrivial coupling between the charge and the magnetization due to the chiral anomaly. By solving the Landau-Lifshitz-Gilbert equation for a multilayer structure of a Weyl semimetal, an insulator and a metal while taking the charge-magnetization coupling into account, magnetization dynamics is analyzed. It is shown that the magnetization dynamics can be driven by the electric voltage. Consequently, switching of the magnetization with a pulsed electric voltage can be achieved, as well as precession motion with an applied oscillating electric voltage. The effect requires only a short voltage pulse and may therefore be energetically favorable for us in spintronics devices compared to conventional spin-transfer torque switching.

  3. Relative Advantages of Direct and Indirect Drive for an Inertial Fusion Energy Power Plant Driven by a Diode-Pumped Solid-State Laser

    NASA Astrophysics Data System (ADS)

    Orth, C. D.

    2001-03-01

    This paper reviews our current understanding of the relative advantages of direct drive (DD) and indirect drive (ID) for a 1 GWe inertial fusion energy (IFE) power plant driven by a diode-pumped solid-state laser (DPSSL). This comparison is motivated by a recent study (1) that shows that the projected cost of electricity (COE) for DD is actually about the same as that for ID even though the target gain for DD can be much larger. We can therefore no longer assume that DD is the ultimate targeting scenario for IFE, and must begin a more rigorous comparison of these two drive options. The comparison begun here shows that ID may actually end up being preferred, but the uncertainties are still rather large.

  4. AC motor and generator requirements for isolated WECS

    NASA Technical Reports Server (NTRS)

    Park, G. L.; Mccleer, P. J.; Hanson, B.; Weinberg, B.; Krauss, O.

    1985-01-01

    After surveying electrically driven loads used on productive farms, the investigators chose three pumps for testing at voltages and frequencies far outside the normal operating range. These loads extract and circulate water and move heat via air, and all are critical to farm productivity. The object was to determine the envelope of supply voltage and frequency over which these loads would operate stably for time intervals under 1 hour. This information is among that needed to determine the feasibility of supplying critical loads, in case of a utility outage, from a wind driven alternator whose output voltage and frequency will vary dramatically in most continental wind regimes. Other related work is surveyed. The salient features and limitations of the test configurations used and the data reduction are described. The development of simulation models suitable for a small computer are outlined. The results are primarily displayed on the voltage frequency plane with the general conclusion that the particular pump models considered will operate over the range of 50 to 90 Hz and a voltage band which starts below rated, decreases as frequency decreases, and is limited on the high side by excessive motor heating. For example, centrifugal pump operating voltage ranges as extensive .4 to 1.4 appear possible. Particular problems with starting, stalling due to lack of motor torque, high speed cavitation, and likely overheating are addressed in a listing of required properties for wind driven alternators and their controllers needed for use in the isolated or stand alone configuration considered.

  5. Bio-inspired polymer composite actuator and generator driven by water gradients.

    PubMed

    Ma, Mingming; Guo, Liang; Anderson, Daniel G; Langer, Robert

    2013-01-11

    Here we describe the development of a water-responsive polymer film. Combining both a rigid matrix (polypyrrole) and a dynamic network (polyol-borate), strong and flexible polymer films were developed that can exchange water with the environment to induce film expansion and contraction, resulting in rapid and continuous locomotion. The film actuator can generate contractile stress up to 27 megapascals, lift objects 380 times heavier than itself, and transport cargo 10 times heavier than itself. We have assembled a generator by associating this actuator with a piezoelectric element. Driven by water gradients, this generator outputs alternating electricity at ~0.3 hertz, with a peak voltage of ~1.0 volt. The electrical energy is stored in capacitors that could power micro- and nanoelectronic devices.

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Galambos, Paul C.

    This is the latest in a series of LDRD's that we have been conducting with Florida State University/Florida A&M University (FSU/FAMU) under the campus executive program. This research builds on the earlier projects; ''Development of Highly Integrated Magnetically and Electrostatically Actuated Micropumps'' (SAND2003-4674) and ''Development of Magnetically and Electrostatically Driven Surface Micromachined Pumps'' (SAND2002-0704P). In this year's LDRD we designed 2nd generation of surface micromachined (SMM) gear and viscous pumps. Two SUMMiT{trademark} modules full of design variations of these pumps were fabricated and one SwIFT{trademark} module is still in fabrication. The SwIFT{trademark} fabrication process results in a transparent pump housingmore » cover that will enable visualization inside the pumps. Since the SwIFT{trademark} pumps have not been tested as they are still in fabrication, this report will focus on the 2nd generation SUMMiT{trademark} designs. Pump testing (pressure vs. flow) was conducted on several of the SUMMiT{trademark} designs resulting in the first pump curve for this class of SMM pumps. A pump curve was generated for the higher torque 2nd generation gear pump designed by Jason Hendrix of FSU. The pump maximum flow rate at zero head was 6.5 nl/s for a 30V, 30 Hz square wave signal. This level of flow rate would be more than adequate for our typical SMM SUMMiT{trademark} or SwIFT{trademark} channels which have typical volumes on the order of 50 pl.« less

  7. NanoShuttles: Harnessing Motor Proteins to Transport Cargo in Synthetic Environments

    NASA Astrophysics Data System (ADS)

    Vogel, V.; Hess, H.

    Motors have become a crucial commodity in our daily lives, from transportation to driving conveyor belts that enable the sequential assembly of cars and other industrial machines. For the sequential assembly of building blocks at the nanoscale that would not assemble spontaneously into larger functional systems, however, active transport systems are not yet available. In contrast, cells have evolved sophisticated molecular machinery that drives movement and active transport. Driven by the conversion of chemical into mechanical energy, namely through hydrolysis of the biological fuel ATP, molecular motors enable cells to operate far away from equilibrium by transporting organelles and molecules to designated locations within the cell, often against concentration gradients. Inspired by the biological concept of active transport, major efforts are underway to learn how to build nanoscale transport systems that are driven by molecular motors. Emerging engineering principles are discussed of how to build tracks and junctions to guide such nanoshuttles, how to load them with cargo and control their speed, how to use active transport to assemble mesoscopic structures that would otherwise not assemble spontaneously and what polymeric materials to choose to integrate motors into MEMS and other biohybrid devices. Finally, two applications that exploit the physical properties of microtubules are discussed, surface imaging by a swarm of microtubules and a self-assembled picoNewton force meter to probe receptor-ligand interactions.

  8. Synthetic Nano- and Micromachines in Analytical Chemistry: Sensing, Migration, Capture, Delivery, and Separation.

    PubMed

    Duan, Wentao; Wang, Wei; Das, Sambeeta; Yadav, Vinita; Mallouk, Thomas E; Sen, Ayusman

    2015-01-01

    Synthetic nano- and microscale machines move autonomously in solution or drive fluid flows by converting sources of energy into mechanical work. Their sizes are comparable to analytes (sub-nano- to microscale), and they respond to signals from each other and their surroundings, leading to emergent collective behavior. These machines can potentially enable hitherto difficult analytical applications. In this article, we review the development of different classes of synthetic nano- and micromotors and pumps and indicate their possible applications in real-time in situ chemical sensing, on-demand directional transport, cargo capture and delivery, as well as analyte isolation and separation.

  9. Structural basis for nuclear import complex dissociation by RanGTP.

    PubMed

    Lee, Soo Jae; Matsuura, Yoshiyuki; Liu, Sai Man; Stewart, Murray

    2005-06-02

    Nuclear protein import is mediated mainly by the transport factor importin-beta that binds cytoplasmic cargo, most often via the importin-alpha adaptor, and then transports it through nuclear pore complexes. This active transport is driven by disassembly of the import complex by nuclear RanGTP. The switch I and II loops of Ran change conformation with nucleotide state, and regulate its interactions with nuclear trafficking components. Importin-beta consists of 19 HEAT repeats that are based on a pair of antiparallel alpha-helices (referred to as the A- and B-helices). The HEAT repeats stack to yield two C-shaped arches, linked together to form a helicoidal molecule that has considerable conformational flexibility. Here we present the structure of full-length yeast importin-beta (Kap95p or karyopherin-beta) complexed with RanGTP, which provides a basis for understanding the crucial cargo-release step of nuclear import. We identify a key interaction site where the RanGTP switch I loop binds to the carboxy-terminal arch of Kap95p. This interaction produces a change in helicoidal pitch that locks Kap95p in a conformation that cannot bind importin-alpha or cargo. We suggest an allosteric mechanism for nuclear import complex disassembly by RanGTP.

  10. Optical silencing of body wall muscles induces pumping inhibition in Caenorhabditis elegans

    PubMed Central

    Takahashi, Megumi

    2017-01-01

    Feeding, a vital behavior in animals, is modulated depending on internal and external factors. In the nematode Caenorhabditis elegans, the feeding organ called the pharynx ingests food by pumping driven by the pharyngeal muscles. Here we report that optical silencing of the body wall muscles, which drive the locomotory movement of worms, affects pumping. In worms expressing the Arch proton pump or the ACR2 anion channel in the body wall muscle cells, the pumping rate decreases after activation of Arch or ACR2 with light illumination, and recovers gradually after terminating illumination. Pumping was similarly inhibited by illumination in locomotion-defective mutants carrying Arch, suggesting that perturbation of locomotory movement is not critical for pumping inhibition. Analysis of mutants and cell ablation experiments showed that the signals mediating the pumping inhibition response triggered by activation of Arch with weak light are transferred mainly through two pathways: one involving gap junction-dependent mechanisms through pharyngeal I1 neurons, which mediate fast signals, and the other involving dense-core vesicle-dependent mechanisms, which mediate slow signals. Activation of Arch with strong light inhibited pumping strongly in a manner that does not rely on either gap junction-dependent or dense-core vesicle-dependent mechanisms. Our study revealed a new aspect of the neural and neuroendocrine controls of pumping initiated from the body wall muscles. PMID:29281635

  11. In-situ Condition Monitoring of Components in Small Modular Reactors Using Process and Electrical Signature Analysis. Final report, volume 1. Development of experimental flow control loop, data analysis and plant monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Upadhyaya, Belle; Hines, J. Wesley; Damiano, Brian

    The research and development under this project was focused on the following three major objectives: Objective 1: Identification of critical in-vessel SMR components for remote monitoring and development of their low-order dynamic models, along with a simulation model of an integral pressurized water reactor (iPWR). Objective 2: Development of an experimental flow control loop with motor-driven valves and pumps, incorporating data acquisition and on-line monitoring interface. Objective 3: Development of stationary and transient signal processing methods for electrical signatures, machinery vibration, and for characterizing process variables for equipment monitoring. This objective includes the development of a data analysis toolbox. Themore » following is a summary of the technical accomplishments under this project: - A detailed literature review of various SMR types and electrical signature analysis of motor-driven systems was completed. A bibliography of literature is provided at the end of this report. Assistance was provided by ORNL in identifying some key references. - A review of literature on pump-motor modeling and digital signal processing methods was performed. - An existing flow control loop was upgraded with new instrumentation, data acquisition hardware and software. The upgrading of the experimental loop included the installation of a new submersible pump driven by a three-phase induction motor. All the sensors were calibrated before full-scale experimental runs were performed. - MATLAB-Simulink model of a three-phase induction motor and pump system was completed. The model was used to simulate normal operation and fault conditions in the motor-pump system, and to identify changes in the electrical signatures. - A simulation model of an integral PWR (iPWR) was updated and the MATLAB-Simulink model was validated for known transients. The pump-motor model was interfaced with the iPWR model for testing the impact of primary flow perturbations (upsets) on plant parameters and the pump electrical signatures. Additionally, the reactor simulation is being used to generate normal operation data and data with instrumentation faults and process anomalies. A frequency controller was interfaced with the motor power supply in order to vary the electrical supply frequency. The experimental flow control loop was used to generate operational data under varying motor performance characteristics. Coolant leakage events were simulated by varying the bypass loop flow rate. The accuracy of motor power calculation was improved by incorporating the power factor, computed from motor current and voltage in each phase of the induction motor.- A variety of experimental runs were made for steady-state and transient pump operating conditions. Process, vibration, and electrical signatures were measured using a submersible pump with variable supply frequency. High correlation was seen between motor current and pump discharge pressure signal; similar high correlation was exhibited between pump motor power and flow rate. Wide-band analysis indicated high coherence (in the frequency domain) between motor current and vibration signals. - Wide-band operational data from a PWR were acquired from AMS Corporation and used to develop time-series models, and to estimate signal spectrum and sensor time constant. All the data were from different pressure transmitters in the system, including primary and secondary loops. These signals were pre-processed using the wavelet transform for filtering both low-frequency and high-frequency bands. This technique of signal pre-processing provides minimum distortion of the data, and results in a more optimal estimation of time constants of plant sensors using time-series modeling techniques.« less

  12. Basic fluid system trainer

    DOEpatents

    Semans, Joseph P.; Johnson, Peter G.; LeBoeuf, Jr., Robert F.; Kromka, Joseph A.; Goron, Ronald H.; Hay, George D.

    1993-01-01

    A trainer, mounted and housed within a mobile console, is used to teach and reinforce fluid principles to students. The system trainer has two centrifugal pumps, each driven by a corresponding two-speed electric motor. The motors are controlled by motor controllers for operating the pumps to circulate the fluid stored within a supply tank through a closed system. The pumps may be connected in series or in parallel. A number of valves are also included within the system to effect different flow paths for the fluid. In addition, temperature and pressure sensing instruments are installed throughout the closed system for measuring the characteristics of the fluid, as it passes through the different valves and pumps. These measurements are indicated on a front panel mounted to the console, as a teaching aid, to allow the students to observe the characteristics of the system.

  13. Changes in ocean circulation and carbon storage are decoupled from air-sea CO2 fluxes

    NASA Astrophysics Data System (ADS)

    Marinov, I.; Gnanadesikan, A.

    2011-02-01

    The spatial distribution of the air-sea flux of carbon dioxide is a poor indicator of the underlying ocean circulation and of ocean carbon storage. The weak dependence on circulation arises because mixing-driven changes in solubility-driven and biologically-driven air-sea fluxes largely cancel out. This cancellation occurs because mixing driven increases in the poleward residual mean circulation result in more transport of both remineralized nutrients and heat from low to high latitudes. By contrast, increasing vertical mixing decreases the storage associated with both the biological and solubility pumps, as it decreases remineralized carbon storage in the deep ocean and warms the ocean as a whole.

  14. Changes in ocean circulation and carbon storage are decoupled from air-sea CO2 fluxes

    NASA Astrophysics Data System (ADS)

    Marinov, I.; Gnanadesikan, A.

    2010-11-01

    The spatial distribution of the air-sea flux of carbon dioxide is a poor indicator of the underlying ocean circulation and of ocean carbon storage. The weak dependence on circulation arises because mixing-driven changes in solubility-driven and biologically-driven air-sea fluxes largely cancel out. This cancellation occurs because mixing driven increases in the poleward residual mean circulation results in more transport of both remineralized nutrients and heat from low to high latitudes. By contrast, increasing vertical mixing decreases the storage associated with both the biological and solubility pumps, as it decreases remineralized carbon storage in the deep ocean and warms the ocean as a whole.

  15. TEM Pump With External Heat Source And Sink

    NASA Technical Reports Server (NTRS)

    Nesmith, Bill J.

    1991-01-01

    Proposed thermoelectric/electromagnetic (TEM) pump driven by external source of heat and by two or more heat pipe radiator heat sink(s). Thermoelectrics generate electrical current to circulate liquid metal in secondary loop of two-fluid-loop system. Intended for use with space and terrestrial dual loop liquid metal nuclear reactors. Applications include spacecraft on long missions or terrestrial beacons or scientific instruments having to operate in remote areas for long times. Design modified to include multiple radiators, converters, and ducts, as dictated by particular application.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Demidov, V. E.; Dzyapko, O.; Demokritov, S. O.

    The room-temperature dynamics of a magnon gas driven by short microwave pumping pulses is studied. An overpopulation of the lowest energy level of the system following the pumping is observed. Using the sensitivity of the Brillouin light scattering technique to the coherence degree of the scattering magnons we demonstrate the spontaneous emergence of coherence of the magnons at the lowest level, if their density exceeds a critical value. This finding is clear proof of the quantum nature of the observed phenomenon and direct evidence of Bose-Einstein condensation of magnons at room temperature.

  17. Simulation of an ammonia-water heat pump water heater with combustion products-driven evaporator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perez-Blanco, Horacio; Gluesenkamp, K.; Ally, Moonis Raza

    Here, the objective of this work is to simulate a single effct (SE) ammonia-water heat pump for domestic water heating, with innovative aspects for cycle simulation and eventual implementation. Seasonal temperature variations demand verfication of distillation column viability. For the given application and temperature ranges, it is found that some variables need to be controlled if the same column is to be used all year round. In addition, a number of simplifications are considered in this work: an advanced evaporator requireing minimal gas flow and surface area, subcooling at two crucial spots of the cycle and the viability of somemore » pump designs to assuage cavitation issues.« less

  18. Simulation of an ammonia-water heat pump water heater with combustion products-driven evaporator

    DOE PAGES

    Perez-Blanco, Horacio; Gluesenkamp, K.; Ally, Moonis Raza

    2016-12-19

    Here, the objective of this work is to simulate a single effct (SE) ammonia-water heat pump for domestic water heating, with innovative aspects for cycle simulation and eventual implementation. Seasonal temperature variations demand verfication of distillation column viability. For the given application and temperature ranges, it is found that some variables need to be controlled if the same column is to be used all year round. In addition, a number of simplifications are considered in this work: an advanced evaporator requireing minimal gas flow and surface area, subcooling at two crucial spots of the cycle and the viability of somemore » pump designs to assuage cavitation issues.« less

  19. Effect of collisions on amplification of laser beams by Brillouin scattering in plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Humphrey, K. A.; Speirs, D. C.; Trines, R. M. G. M.

    2013-10-15

    We report on particle in cell simulations of energy transfer between a laser pump beam and a counter-propagating seed beam using the Brillouin scattering process in uniform plasma including collisions. The results presented show that the ion acoustic waves excited through naturally occurring Brillouin scattering of the pump field are preferentially damped without affecting the driven Brillouin scattering process resulting from the beating of the pump and seed fields together. We find that collisions, including the effects of Landau damping, allow for a more efficient transfer of energy between the laser beams, and a significant reduction in the amount ofmore » seed pre-pulse produced.« less

  20. Biphoton Generation Driven by Spatial Light Modulation: Parallel-to-Series Conversion

    NASA Astrophysics Data System (ADS)

    Zhao, Luwei; Guo, Xianxin; Sun, Yuan; Su, Yumian; Loy, M. M. T.; Du, Shengwang

    2016-05-01

    We demonstrate the generation of narrowband biphotons with controllable temporal waveform by spontaneous four-wave mixing in cold atoms. In the group-delay regime, we study the dependence of the biphoton temporal waveform on the spatial profile of the pump laser beam. By using a spatial light modulator, we manipulate the spatial profile of the pump laser and map it onto the two-photon entangled temporal wave function. This parallel-to-series conversion (or spatial-to-temporal mapping) enables coding the parallel classical information of the pump spatial profile to the sequential temporal waveform of the biphoton quantum state. The work was supported by the Hong Kong RGC (Project No. 601113).

  1. The HALNA project: Diode-pumped solid-state laser for inertial fusion energy

    NASA Astrophysics Data System (ADS)

    Kawashima, T.; Ikegawa, T.; Kawanaka, J.; Miyanaga, N.; Nakatsuka, M.; Izawa, Y.; Matsumoto, O.; Yasuhara, R.; Kurita, T.; Sekine, T.; Miyamoto, M.; Kan, H.; Furukawa, H.; Motokoshi, S.; Kanabe, T.

    2006-06-01

    High-enery, rep.-rated, diode-pumped solid-state laser (DPSSL) is one of leading candidates for inertial fusion energy driver (IFE) and related laser-driven high-field applications. The project for the development of IFE laser driver in Japan, HALNA (High Average-power Laser for Nuclear Fusion Application) at ILE, Osaka University, aims to demonstrate 100-J pulse energy at 10 Hz rep. rate with 5 times diffraction limited beam quality. In this article, the advanced solid-state laser technologies for one half scale of HALNA (50 J, 10 Hz) are presented including thermally managed slab amplifier of Nd:phosphate glass and zig-zag optical geometry, and uniform, large-area diode-pumping.

  2. Challenges in realizing a self-contained hydraulically-driven contractile fiber actuator.

    PubMed

    Smela, Elisabeth

    2017-07-01

    The field of soft robots would benefit from electrically controlled contractile actuators in the form of fibers that achieve a strain of 20% in less than a second while exerting high force. This work explores possible designs for achieving this goal using self-contained electroosmotic fluid pumping within a tube-shaped structure. The most promising configuration is a combination of a bellows and a McKibben-type muscle, since pumping fluid from the former to the latter results in contraction of both portions. Realizing such a device entails challenges in fabrication and electrokinetic fluid pumping in closed systems. Further studies of electroosmotic flow in salt-free organic solvents are needed.

  3. Chevrons, filaments, spinning clusters and phase coexistence: emergent dynamics of 2- and 3-d particle suspensions driven by multiaxial magnetic fields

    DOE PAGES

    Solis, Kyle J.; Martin, James E.

    2017-07-06

    In recent years a rich variety of emergent phenomena have been observed when suspensions of magnetic particles are subjected to alternating magnetic fields. These particle assemblies often exhibit vigorous dynamics due to the injection of energy from the field. These include surface and interface phenomena, such as highly organized, segmented “snakes” that can be induced to swim by structural symmetry breaking, and “asters” and “anti-asters,” particle assemblies that can be manipulated to capture and transport cargo. In bulk suspensions of magnetic platelets subjected to multiaxial alternating fields, advection lattices and even vortex lattices have been created, and a variety ofmore » biomimetic dynamics – serpents, bees and amoebas – have been discovered in magnetic fluids suspended in an immiscible liquid. In this paper several new driven phases are presented, including flying chevrons, dense spinning clusters, filaments, and examples of phase coexistence in driven phases. These observations broaden the growing field of driven magnetic suspensions and present new challenges to those interested in simulating the dynamics of these complex systems.« less

  4. Impact of anatase and rutile titanium dioxide nanoparticles on uptake carriers and efflux pumps in Caco-2 gut epithelial cells.

    PubMed

    Dorier, M; Brun, E; Veronesi, G; Barreau, F; Pernet-Gallay, K; Desvergne, C; Rabilloud, T; Carapito, C; Herlin-Boime, N; Carrière, M

    2015-04-28

    TiO2 microparticles are widely used in food products, where they are added as a white food colouring agent. This food additive contains a significant amount of nanoscale particles; still the impact of TiO2 nanoparticles (TiO2-NPs) on gut cells is poorly documented. Our study aimed at evaluating the impact of rutile and anatase TiO2-NPs on the main functions of enterocytes, i.e. nutrient absorption driven by solute-liquid carriers (SLC transporters) and protection against other xenobiotics driven by efflux pumps from the ATP-binding cassette (ABC) family. We show that acute exposure of Caco-2 cells to both anatase (12 nm) and rutile (20 nm) TiO2-NPs induce early upregulation of a battery of efflux pumps and nutrient transporters. In addition they cause overproduction of reactive oxygen species and misbalance redox repair systems, without inducing cell mortality or DNA damage. Taken together, these data suggest that TiO2-NPs may increase the functionality of gut epithelial cells, particularly their property to form a protective barrier against exogenous toxicants and to absorb nutrients.

  5. Heating and thermal squeezing in parametrically driven oscillators with added noise.

    PubMed

    Batista, Adriano A

    2012-11-01

    In this paper we report a theoretical model based on Green's functions, Floquet theory, and averaging techniques up to second order that describes the dynamics of parametrically driven oscillators with added thermal noise. Quantitative estimates for heating and quadrature thermal noise squeezing near and below the transition line of the first parametric instability zone of the oscillator are given. Furthermore, we give an intuitive explanation as to why heating and thermal squeezing occur. For small amplitudes of the parametric pump the Floquet multipliers are complex conjugate of each other with a constant magnitude. As the pump amplitude is increased past a threshold value in the stable zone near the first parametric instability, the two Floquet multipliers become real and have different magnitudes. This creates two different effective dissipation rates (one smaller and the other larger than the real dissipation rate) along the stable manifolds of the first-return Poincaré map. We also show that the statistical average of the input power due to thermal noise is constant and independent of the pump amplitude and frequency. The combination of these effects causes most of heating and thermal squeezing. Very good agreement between analytical and numerical estimates of the thermal fluctuations is achieved.

  6. Excitonic gap formation in pumped Dirac materials

    NASA Astrophysics Data System (ADS)

    Triola, Christopher; Pertsova, Anna; Markiewicz, Robert S.; Balatsky, Alexander V.

    2017-05-01

    Recent pump-probe experiments demonstrate the possibility that Dirac materials may be driven into transient excited states describable by two chemical potentials, one for the electrons and one for the holes. Given the Dirac nature of the spectrum, such an inverted population allows the optical tunability of the density of states of the electrons and holes, effectively offering control of the strength of the Coulomb interaction. Here we discuss the feasibility of realizing transient excitonic instabilities in optically pumped Dirac materials. We demonstrate, theoretically, the reduction of the critical coupling leading to the formation of a transient condensate of electron-hole pairs and identify signatures of this state. Furthermore, we provide guidelines for experiments by both identifying the regimes in which such exotic many-body states are more likely to be observed and estimating the magnitude of the excitonic gap for a few important examples of existing Dirac materials. We find a set of material parameters for which our theory predicts large gaps and high critical temperatures and which could be realized in future Dirac materials. We also comment on transient excitonic instabilities in three-dimensional Dirac and Weyl semimetals. This study provides an example of a transient collective instability in driven Dirac materials.

  7. Atomic Force Microscope Mediated Chromatography

    NASA Technical Reports Server (NTRS)

    Anderson, Mark S.

    2013-01-01

    The atomic force microscope (AFM) is used to inject a sample, provide shear-driven liquid flow over a functionalized substrate, and detect separated components. This is demonstrated using lipophilic dyes and normal phase chromatography. A significant reduction in both size and separation time scales is achieved with a 25-micron-length column scale, and one-second separation times. The approach has general applications to trace chemical and microfluidic analysis. The AFM is now a common tool for ultra-microscopy and nanotechnology. It has also been demonstrated to provide a number of microfluidic functions necessary for miniaturized chromatography. These include injection of sub-femtoliter samples, fluidic switching, and sheardriven pumping. The AFM probe tip can be used to selectively remove surface layers for subsequent microchemical analysis using infrared and tip-enhanced Raman spectroscopy. With its ability to image individual atoms, the AFM is a remarkably sensitive detector that can be used to detect separated components. These diverse functional components of microfluidic manipulation have been combined in this work to demonstrate AFM mediated chromatography. AFM mediated chromatography uses channel-less, shear-driven pumping. This is demonstrated with a thin, aluminum oxide substrate and a non-polar solvent system to separate a mixture of lipophilic dyes. In conventional chromatographic terms, this is analogous to thin-layer chromatography using normal phase alumina substrate with sheardriven pumping provided by the AFM tip-cantilever mechanism. The AFM detection of separated components is accomplished by exploiting the variation in the localized friction of the separated components. The AFM tip-cantilever provides the mechanism for producing shear-induced flows and rapid pumping. Shear-driven chromatography (SDC) is a relatively new concept that overcomes the speed and miniaturization limitations of conventional liquid chromatography. SDC is based on a sliding plate system, consisting of two flat surfaces, one of which has a recessed channel. A fluid flow is produced by axially sliding one plate past another, where the fluid has mechanical shear forces imposed at each point along the channel length. The shear-induced flow rates are very reproducible, and do not have pressure or voltage gradient limitations. SDC opens up a new range of enhanced separation kinetics by permitting the sample confinement with submicron dimensions. Small, highly confined liquid is advantageous for chromatographic separation because the separation rate is known to scale according to the square of the confined sample diameter. In addition, because shear-driven flows are not limited by fluid velocity, shear-driven liquid chromatography may provide up to 100,000 plate efficiency.

  8. Optimizing the longitudinal and transverse electroosmotic pumping in a rectangular channel with horizontal baffle plates

    NASA Astrophysics Data System (ADS)

    Lai, Anison K. R.; Chang, Chien-Cheng; Wang, Chang-Yi

    2018-04-01

    This paper presents a continued study to our previous work on electroosmotic (EO) flow in a channel with vertical baffle plates by further investigating EO flow through an array of baffle plates arranged in parallel to the channel walls. The flow may be driven either in the direction along or in the direction transverse to the plates, thus distinguishing the longitudinal EO pumping (LEOP) and the transverse EO pumping (TEOP). In both types of EO pumping, it is more interesting to examine the cases when the baffle plates develop a higher zeta potential (denoted by α) than that on the channel walls (β). This semi-analytical study enables us to compare between LEOP and TEOP in the pumping efficiency under similar conditions. The TEOP case is more difficult to solve due to the higher order governing partial differential equations caused by the induced non-uniform pressure gradient distribution. In particular, we examine how the EO pumping rates deviate from those predicted by the Helmholtz-Smoluchowski velocity and illustrate the general trend of optimizing the EO pumping rates with respect to the physical and geometric parameters involved.

  9. Development of a programmable piggyback syringe pump and four-times-a-day injection regimen for superovulation in non-lactating Holstein cows

    PubMed Central

    IRSHAD, Abdul Razaq; SASAKI, Taihei; KUBO, Tomoaki; ODASHIMA, Naoyuki; KATANO, Keiji; OSAWA, Takeshi; TAKAHASHI, Toru; IZAIKE, Yoshiaki

    2015-01-01

    The objectives of the present study were to develop a programmable piggyback syringe pump for bovine superovulation and to evaluate the effects of a four-times-a-day injection regimen using the pump. Non-lactating Holstein cows were treated with a total of 30 armour units of porcine FSH by injection four times a day with the pump (study, n = 9) or injection twice a day manually (control, n = 9) for four consecutive days from D10 of the estrous cycle. The pump-driven program successfully induced superovulation in all cows tested. The numbers of small (3– < 5 mm in diameter) and large (≥ 10 mm in diameter) follicles were greater in the study group on D11-13 and D14, respectively. There were fewer unovulated follicles detected on D21 (7 days after estrus) in the study group than in the control group (1.2 ± 0.4 and 3.2 ± 0.6, respectively). PMID:26052155

  10. Development of a programmable piggyback syringe pump and four-times-a-day injection regimen for superovulation in non-lactating Holstein cows.

    PubMed

    Irshad, Abdul Razaq; Sasaki, Taihei; Kubo, Tomoaki; Odashima, Naoyuki; Katano, Keiji; Osawa, Takeshi; Takahashi, Toru; Izaike, Yoshiaki

    2015-01-01

    The objectives of the present study were to develop a programmable piggyback syringe pump for bovine superovulation and to evaluate the effects of a four-times-a-day injection regimen using the pump. Non-lactating Holstein cows were treated with a total of 30 armour units of porcine FSH by injection four times a day with the pump (study, n = 9) or injection twice a day manually (control, n = 9) for four consecutive days from D10 of the estrous cycle. The pump-driven program successfully induced superovulation in all cows tested. The numbers of small (3- < 5 mm in diameter) and large (≥ 10 mm in diameter) follicles were greater in the study group on D11-13 and D14, respectively. There were fewer unovulated follicles detected on D21 (7 days after estrus) in the study group than in the control group (1.2 ± 0.4 and 3.2 ± 0.6, respectively).

  11. Matter wave coupling of spatially separated and unequally pumped polariton condensates

    NASA Astrophysics Data System (ADS)

    Kalinin, Kirill P.; Lagoudakis, Pavlos G.; Berloff, Natalia G.

    2018-03-01

    Spatial quantum coherence between two separated driven-dissipative polariton condensates created nonresonantly and with a different occupation is studied. We identify the regions where the condensates remain coherent with the phase difference continuously changing with the pumping imbalance and the regions where each condensate acquires its own chemical potential with phase differences exhibiting time-dependent oscillations. We show that in the mutual coherence limit the coupling consists of two competing contributions: a symmetric Heisenberg exchange and the Dzyloshinskii-Moriya asymmetric interactions that enable a continuous tuning of the phase relation across the dyad and derive analytic expressions for these types of interactions. The introduction of nonequal pumping increases the complexity of the type of problems that can be solved by polariton condensates arranged in a graph configuration. If equally pumped polaritons condensates arrange their phases to solve the constrained quadratic minimisation problem with a real symmetric matrix, the nonequally pumped condensates solve that problem for a general Hermitian matrix.

  12. A Superfluid Pulse Tube Refrigerator Without Moving Parts for Sub-Kelvin Cooling

    NASA Technical Reports Server (NTRS)

    Miller, Franklin K.

    2012-01-01

    A report describes a pulse tube refrigerator that uses a mixture of He-3 and superfluid He-4 to cool to temperatures below 300 mK, while rejecting heat at temperatures up to 1.7 K. The refrigerator is driven by a novel thermodynamically reversible pump that is capable of pumping the He-3 He-4 mixture without the need for moving parts. The refrigerator consists of a reversible thermal magnetic pump module, two warm heat exchangers, a recuperative heat exchanger, two cold heat exchangers, two pulse tubes, and an orifice. It is two superfluid pulse tubes that run 180 out of phase. All components of this machine except the reversible thermal pump have been demonstrated at least as proof-of-concept physical models in previous superfluid Stirling cycle machines. The pump consists of two canisters packed with pieces of gadolinium gallium garnet (GGG). The canisters are connected by a superleak (a porous piece of VYCOR glass). A superconducting magnetic coil surrounds each of the canisters.

  13. Metal-Organic Frameworks in Adsorption-Driven Heat Pumps: The Potential of Alcohols as Working Fluids.

    PubMed

    de Lange, Martijn F; van Velzen, Benjamin L; Ottevanger, Coen P; Verouden, Karlijn J F M; Lin, Li-Chiang; Vlugt, Thijs J H; Gascon, Jorge; Kapteijn, Freek

    2015-11-24

    A large fraction of global energy is consumed for heating and cooling. Adsorption-driven heat pumps and chillers could be employed to reduce this consumption. MOFs are often considered to be ideal adsorbents for heat pumps and chillers. While most published works to date on this topic have focused on the use of water as a working fluid, the instability of many MOFs to water and the fact that water cannot be used at subzero temperatures pose certain drawbacks. The potential of using alcohol-MOF pairs in adsorption-driven heat pumps and chillers is investigated. To this end, 18 different selected MOF structures in combination with either methanol or ethanol as a working fluid are considered, and their potential is assessed on the basis of adsorption measurements and thermodynamic efficiencies. If alcohols are used instead of water, then (1) adsorption occurs at lower relative pressures for methanol and even lower pressure for ethanol, (2) larger pores can be utilized efficiently, as hysteresis is absent for pores smaller than 3.4 nm (2 nm for water), (3) larger pore sizes need to be employed to ensure the desired stepwise adsorption, (4) the effect of (polar/apolar) functional groups in the MOF is far less pronounced, (5) the energy released or taken up per cycle is lower, but heat and mass transfer may be enhanced, (6) stability of MOFs seems to be less of an issue, and (7) cryogenic applications (e.g., ice making) become feasible. From a thermodynamic perspective, UiO-67, CAU-3, and ZIF-8 seem to be the most promising MOFs for both methanol and ethanol as working fluids. Although UiO-67 might not be completely stable, both CAU-3 and ZIF-8 have the potential to be applied, especially in subzero-temperature adsorption chillers (AC).

  14. Heat transfer implications in the first MEMS fabricated thermal transiration-driven vacuum pump for gases

    NASA Technical Reports Server (NTRS)

    Vargo, S. E.; Green, A. A.; Muntz, E. P.

    2000-01-01

    The success of NASA's future space missions and the development of portable, commercial instrument packages will depend greatly on miniaturized components enabled by the use of microelectromechanical systems (MEMS).

  15. 46 CFR 131.340 - Recommended placard for emergency instructions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Keep bilges dry to prevent loss of stability from water in bilges. Use power-driven bilge pump, hand... any fixed extinguishing-system. (5) Maneuver the vessel to minimize the effect of wind on the fire. (6...

  16. Light energy conservation processes in Halobacterium halobium cells

    NASA Technical Reports Server (NTRS)

    Bogomolni, R. A.

    1977-01-01

    Proton pumping driven by light or by respiration generates an electrochemical potential difference across the membrane in Halobacterium halobium. The pH changes induced by light or by respiration in cell suspensions are complicated by proton flows associated with the functioning of the cellular energy transducers. A proton-per-ATP ratio of about 3 is calculated from simultaneous measurements of phosphorylation and the proton inflow. This value is compatible with the chemiosmotic coupling hypothesis. The time course of the light-induced changes in membrane potential indicates that light-driven pumping increases a dark pre-existing potential of about 130 mV only by a small amount (20 to 30 mV). The complex kinetic features of the membrane potential changes do not closely follow those of the pH changes, which suggests that flows of ions other than protons are involved. A qualitative model consistent with the available data is presented.

  17. Gas engine heat pump cycle analysis. Volume 1: Model description and generic analysis

    NASA Astrophysics Data System (ADS)

    Fischer, R. D.

    1986-10-01

    The task has prepared performance and cost information to assist in evaluating the selection of high voltage alternating current components, values for component design variables, and system configurations and operating strategy. A steady-state computer model for performance simulation of engine-driven and electrically driven heat pumps was prepared and effectively used for parametric and seasonal performance analyses. Parametric analysis showed the effect of variables associated with design of recuperators, brine coils, domestic hot water heat exchanger, compressor size, engine efficiency, insulation on exhaust and brine piping. Seasonal performance data were prepared for residential and commercial units in six cities with system configurations closely related to existing or contemplated hardware of the five GRI engine contractors. Similar data were prepared for an advanced variable-speed electric unit for comparison purposes. The effect of domestic hot water production on operating costs was determined. Four fan-operating strategies and two brine loop configurations were explored.

  18. A Simplified Method for Sampling and Analysis of High Volume Surface Water for Organic Contaminants Using XAD-2

    USGS Publications Warehouse

    Datta, S.; Do, L.V.; Young, T.M.

    2004-01-01

    A simple compressed-gas driven system for field processing and extracting water for subsequent analyses of hydrophobic organic compounds is presented. The pumping device is a pneumatically driven pump and filtration system that can easily clarify at 4L/min. The extraction device uses compressed gas to drive filtered water through two parallel XAD-2 resin columns, at about 200 mL/min. No batteries or inverters are required for water collection or processing. Solvent extractions were performed directly in the XAD-2 glass columns. Final extracts are cleaned-up on Florisil cartridges without fractionation and contaminants analyzed by GC-MS. Method detection limits (MDLs) and recoveries for dissolved organic contaminants, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and pesticides are reported along with results of surface water analysis for the San Francisco Bay, CA.

  19. Space-based laser-powered orbital transfer vehicle (Project SLICK)

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A conceptual design study of a laser-powered orbital transfer vehicle (LOTV) is presented. The LOTV, nicknamed SLICK (Space Laser Interorbital Cargo Kite), will be utilized for the transfer of 16000 kg of cargo between Low Earth Orbit (LEO) and either Geosynchronous Earth Orbit (GEO) or Low Lunar Orbit (LLO). This design concentrates primarily on the LEO/GEO scenario, which will have typical LEO-to-GEO trip time of 6 days and two return versions. One version uses an all propulsive return while the other utilizes a ballute aerobrake for the return trip. Furthermore, three return cargo options of 16000 kg, 5000 kg (standard option), and 1600 kg are considered for this scenario. The LEO/LLO scenario uses only a standard, aerobraked version. The basic concept behind the LOTV is that the power for the propulsion system is supplied by a source separate from the LOTV itself. For the LEO/GEO scenario the LOTV utilizes a direct solar-pumped iodide laser and possibly two relay stations, all orbiting at an altitude of one Earth radius and zero inclination. An additional nuclear-powered laser is placed on the Moon for the LEO/LLO scenario. The propulsion system of the LOTV consists of a single engine fueled with liquid hydrogen. The laser beam is captured and directed by a four mirror optical system through a window in the thrust chamber of the engine. There, seven plasmas are created to convert the laser beam energy into thermal energy at an efficiency of at least 50 percent. For the LEO/LLO scenario the laser propulsion is supplemented by LH2/LOX chemical thrusters.

  20. Comparison Between Individually and Group-Based Insulin Pump Initiation by Time-Driven Activity-Based Costing

    PubMed Central

    Ridderstråle, Martin

    2017-01-01

    Background: Depending on available resources, competencies, and pedagogic preference, initiation of insulin pump therapy can be performed on either an individual or a group basis. Here we compared the two models with respect to resources used. Methods: Time-driven activity-based costing (TDABC) was used to compare initiating insulin pump treatment in groups (GT) to individual treatment (IT). Activities and cost drivers were identified, timed, or estimated at location. Medical quality and patient satisfaction were assumed to be noninferior and were not measured. Results: GT was about 30% less time-consuming and 17% less cost driving per patient and activity compared to IT. As a batch driver (16 patients in one group) GT produced an upward jigsaw-shaped accumulative cost curve compared to the incremental increase incurred by IT. Taking the alternate cost for those not attending into account, and realizing the cost of opportunity gained, suggested that GT was cost neutral already when 5 of 16 patients attended, and that a second group could be initiated at no additional cost as the attendance rate reached 15:1. Conclusions: We found TDABC to be effective in comparing treatment alternatives, improving cost control and decision making. Everything else being equal, if the setup is available, our data suggest that initiating insulin pump treatment in groups is far more cost effective than on an individual basis and that TDABC may be used to find the balance point. PMID:28366085

  1. Self-powered enzyme micropumps

    NASA Astrophysics Data System (ADS)

    Sengupta, Samudra; Patra, Debabrata; Ortiz-Rivera, Isamar; Agrawal, Arjun; Shklyaev, Sergey; Dey, Krishna K.; Córdova-Figueroa, Ubaldo; Mallouk, Thomas E.; Sen, Ayusman

    2014-05-01

    Non-mechanical nano- and microscale pumps that function without the aid of an external power source and provide precise control over the flow rate in response to specific signals are needed for the development of new autonomous nano- and microscale systems. Here we show that surface-immobilized enzymes that are independent of adenosine triphosphate function as self-powered micropumps in the presence of their respective substrates. In the four cases studied (catalase, lipase, urease and glucose oxidase), the flow is driven by a gradient in fluid density generated by the enzymatic reaction. The pumping velocity increases with increasing substrate concentration and reaction rate. These rechargeable pumps can be triggered by the presence of specific analytes, which enables the design of enzyme-based devices that act both as sensor and pump. Finally, we show proof-of-concept enzyme-powered devices that autonomously deliver small molecules and proteins in response to specific chemical stimuli, including the release of insulin in response to glucose.

  2. Apparatus for the conversion of power strokes of a random sequence and of random lengths of strokes into potential energy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elkuch, E.

    1984-01-17

    The apparatus comprises at least one positive displacement pump, which is driven by the sea waves. The quantity of delivery of this pump is adjustable in accordance with the lengths of strokes made by the ocean waves. This is made possible in that the positive displacement pump comprises pistons having different volume displacements. The height of the incoming waves is measured by a membrane box connected to a transducer which generates signals such that only that piston of the plurality of pistons is made to operate, which has by design a volume displacement which gives the optimal recovery of themore » energy of the ocean waves. The or these pistons pump a working fluid into a storage vessel, which allows the generation of peak load as well as base load electrical energy.« less

  3. Bio-inspired Polymer Composite Actuator and Generator Driven by Water Gradients

    PubMed Central

    Ma, Mingming; Guo, Liang; Anderson, Daniel G.; Langer, Robert

    2013-01-01

    Here we describe the development of a water-responsive polymer film; combining both a rigid matrix (polypyrrole) and a dynamic network (polyol-borate), strong and flexible polymer films were developed that can exchange water with the environment to induce film expansion and contraction, resulting in rapid and continuous locomotion. The film actuator can generate contractile stress up to 27 MPa, lift objects 380 times heavier than itself, and transport cargo 10 times heavier than itself. We have assembled a generator by associating this actuator with a piezoelectric element. Driven by water gradients, this generator outputs alternating electricity at ∼0.3 Hz, with a peak voltage of ∼1.0 V. The electrical energy is stored in capacitors that could power micro- and nano-electronic devices. PMID:23307738

  4. Small hydraulic turbine drives

    NASA Technical Reports Server (NTRS)

    Rostafinski, W. A.

    1970-01-01

    Turbine, driven by the fluid being pumped, requires no external controls, is completely integrated into the flow system, and has bearings which utilize the main fluid for lubrication and cooling. Torque capabilities compare favorably with those developed by positive displacement hydraulic motors.

  5. Credit BG. Interior of Deluge Water Booster Station displaying highcapacity ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. Interior of Deluge Water Booster Station displaying high-capacity electrically driven water pumps for fire fighting service - Edwards Air Force Base, North Base, Deluge Water Booster Station, Northeast of A Street, Boron, Kern County, CA

  6. Inductive detection of fieldlike and dampinglike ac inverse spin-orbit torques in ferromagnet/normal-metal bilayers

    NASA Astrophysics Data System (ADS)

    Berger, Andrew J.; Edwards, Eric R. J.; Nembach, Hans T.; Karenowska, Alexy D.; Weiler, Mathias; Silva, Thomas J.

    2018-03-01

    Functional spintronic devices rely on spin-charge interconversion effects, such as the reciprocal processes of electric field-driven spin torque and magnetization dynamics-driven spin and charge flow. Both dampinglike and fieldlike spin-orbit torques have been observed in the forward process of current-driven spin torque and dampinglike inverse spin-orbit torque has been well studied via spin pumping into heavy metal layers. Here, we demonstrate that established microwave transmission spectroscopy of ferromagnet/normal metal bilayers under ferromagnetic resonance can be used to inductively detect the ac charge currents driven by the inverse spin-charge conversion processes. This technique relies on vector network analyzer ferromagnetic resonance (VNA-FMR) measurements. We show that in addition to the commonly extracted spectroscopic information, VNA-FMR measurements can be used to quantify the magnitude and phase of all ac charge currents in the sample, including those due to spin pumping and spin-charge conversion. Our findings reveal that Ni80Fe20/Pt bilayers exhibit both dampinglike and fieldlike inverse spin-orbit torques. While the magnitudes of both the dampinglike and fieldlike inverse spin-orbit torque are of comparable scale to prior reported values for similar material systems, we observed a significant dependence of the dampinglike magnitude on the order of deposition. This suggests interface quality plays an important role in the overall strength of the dampinglike spin-to-charge conversion.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Solis, Kyle J.; Martin, James E.

    In recent years a rich variety of emergent phenomena have been observed when suspensions of magnetic particles are subjected to alternating magnetic fields. These particle assemblies often exhibit vigorous dynamics due to the injection of energy from the field. These include surface and interface phenomena, such as highly organized, segmented “snakes” that can be induced to swim by structural symmetry breaking, and “asters” and “anti-asters,” particle assemblies that can be manipulated to capture and transport cargo. In bulk suspensions of magnetic platelets subjected to multiaxial alternating fields, advection lattices and even vortex lattices have been created, and a variety ofmore » biomimetic dynamics – serpents, bees and amoebas – have been discovered in magnetic fluids suspended in an immiscible liquid. In this paper several new driven phases are presented, including flying chevrons, dense spinning clusters, filaments, and examples of phase coexistence in driven phases. These observations broaden the growing field of driven magnetic suspensions and present new challenges to those interested in simulating the dynamics of these complex systems.« less

  8. Design of a high-pressure circulating pump for viscous liquids.

    PubMed

    Seifried, Bernhard; Temelli, Feral

    2009-07-01

    The design of a reciprocating dual action piston pump capable of circulating viscous fluids at pressures of up to 34 MPa (5000 psi) and temperatures up to 80 degrees C is described. The piston of this pump is driven by a pair of solenoids energized alternatively by a 12 V direct current power supply controlled by an electronic controller facilitating continuously adjustable flow rates. The body of this seal-less pump is constructed using off-the-shelf parts eliminating the need for custom made parts. Both the electronic controller and the pump can be assembled relatively easily. Pump performance has been evaluated at room temperature (22 degrees C) and atmospheric pressure using liquids with low and moderately high viscosities, such as ethanol and corn oil, respectively. At ambient conditions, the pump delivered continuous flow of ethanol and corn oil at a flow rate of up to 170 and 17 cm3/min, respectively. For pumping viscous fluids comparable to corn oil, an optimum reciprocation frequency was ascertained to maximize flow rate. For low viscosity liquids such as ethanol, a linear relationship between the flow rate and reciprocation frequency was determined up to the maximum reciprocation frequency of the pump. Since its fabrication, the pump has been used in our laboratory for circulating triglycerides in contact with supercritical carbon dioxide at pressures of up to 25 MPa (3600 psi) and temperatures up to 70 degrees C on a daily basis for a total of more than 1500 h of operation functioning trouble free.

  9. First Evidence of Vibrationally Driven Bimolecular Reactions in Solution: Reactions of Br Atoms with Dimethylsulfoxide and Methanol.

    PubMed

    Shin, Jae Yoon; Shaloski, Michael A; Crim, F Fleming; Case, Amanda S

    2017-03-23

    We present evidence for vibrational enhancement of the rate of bimolecular reactions of Br atoms with dimethylsulfoxide (DMSO) and methanol (CH 3 OH) in the condensed phase. The abstraction of a hydrogen atom from either of these solvents by a Br atom is highly endoergic: 3269 cm -1 for DMSO and 1416 or 4414 cm -1 for CH 3 OH, depending on the hydrogen atom abstracted. Thus, there is no thermal abstraction reaction at room temperature. Broadband electronic transient absorption shows that following photolysis of bromine precursors Br atoms form van der Waals complexes with the solvent molecules in about 5 ps and this Br • -solvent complex undergoes recombination. To explore the influence of vibrational energy on the abstraction reactions, we introduce a near-infrared (NIR) pump pulse following the photolysis pulse to excite the first overtone of the C-H (or O-H) stretch of the solvent molecules. Using single-wavelength detection, we observe a loss of the Br • -solvent complex that requires the presence of both photolysis and NIR pump pulses. Moreover, the magnitude of this loss depends on the NIR wavelength. Although this loss of reactive Br supports the notion of vibrationally driven chemistry, it is not concrete evidence of the hydrogen-abstraction reaction. To verify that the loss of reactive Br results from the vibrationally driven bimolecular reaction, we examine the pH dependence of the solution (as a measure of the formation of the HBr product) following long-time irradiation of the sample with both photolysis and NIR pump beams. We observe that when the NIR beam is on-resonance, the hydronium ion concentration increases fourfold as compared to that when it is off-resonance, suggesting the formation of HBr via a vibrationally driven hydrogen-abstraction reaction in solution.

  10. Enhancement of Survival and Electricity Production in an Engineered Bacterium by Light-Driven Proton Pumping▿ †

    PubMed Central

    Johnson, Ethan T.; Baron, Daniel B.; Naranjo, Belén; Bond, Daniel R.; Schmidt-Dannert, Claudia; Gralnick, Jeffrey A.

    2010-01-01

    Microorganisms can use complex photosystems or light-dependent proton pumps to generate membrane potential and/or reduce electron carriers to support growth. The discovery that proteorhodopsin is a light-dependent proton pump that can be expressed readily in recombinant bacteria enables development of new strategies to probe microbial physiology and to engineer microbes with new light-driven properties. Here, we describe functional expression of proteorhodopsin and light-induced changes in membrane potential in the bacterium Shewanella oneidensis strain MR-1. We report that there were significant increases in electrical current generation during illumination of electrochemical chambers containing S. oneidensis expressing proteorhodopsin. We present evidence that an engineered strain is able to consume lactate at an increased rate when it is illuminated, which is consistent with the hypothesis that proteorhodopsin activity enhances lactate uptake by increasing the proton motive force. Our results demonstrate that there is coupling of a light-driven process to electricity generation in a nonphotosynthetic engineered bacterium. Expression of proteorhodopsin also preserved the viability of the bacterium under nutrient-limited conditions, providing evidence that fulfillment of basic energy needs of organisms may explain the widespread distribution of proteorhodopsin in marine environments. PMID:20453141

  11. Proposal of laser-driven automobile

    NASA Astrophysics Data System (ADS)

    Yabe, Takashi; Oozono, Hirokazu; Taniguchi, Kazumoto; Ohkubo, Tomomasa; Miyazaki, Sho; Uchida, Shigeaki; Baasandash, Choijil

    2004-09-01

    We propose an automobile driven by piston motion, which is driven by water-laser coupling. The automobile can load a solar-pumped fiber laser or can be driven by ground-based lasers. The vehicle is much useful for the use in other planet in which usual combustion engine cannot be used. The piston is in a closed system and then the water will not be exhausted into vacuum. In the preliminary experiment, we succeeded to drive the cylindrical piston of 0.2g (6mm in diameter) on top of water placed inside the acrylic pipe of 8 mm in inner diameter and the laser is incident from the bottom and focused onto the upper part of water by the lens (f=8mm) attached to the bottom edge.

  12. Active control system for high speed windmills

    DOEpatents

    Avery, D.E.

    1988-01-12

    A pump stroke is matched to the operating speed of a high speed windmill. The windmill drives a hydraulic pump for a control. Changes in speed of a wind driven shaft open supply and exhaust valves to opposite ends of a hydraulic actuator to lengthen and shorten an oscillating arm thereby lengthening and shortening the stroke of an output pump. Diminishing wind to a stall speed causes the valves to operate the hydraulic cylinder to shorten the oscillating arm to zero. A pressure accumulator in the hydraulic system provides the force necessary to supply the hydraulic fluid under pressure to drive the actuator into and out of the zero position in response to the windmill shaft speed approaching and exceeding windmill stall speed. 4 figs.

  13. Active control system for high speed windmills

    DOEpatents

    Avery, Don E.

    1988-01-01

    A pump stroke is matched to the operating speed of a high speed windmill. The windmill drives a hydraulic pump for a control. Changes in speed of a wind driven shaft open supply and exhaust valves to opposite ends of a hydraulic actuator to lengthen and shorten an oscillating arm thereby lengthening and shortening the stroke of an output pump. Diminishing wind to a stall speed causes the valves to operate the hydraulic cylinder to shorten the oscillating arm to zero. A pressure accumulator in the hydraulic system provides the force necessary to supply the hydraulic fluid under pressure to drive the actuator into and out of the zero position in response to the windmill shaft speed approaching and exceeding windmill stall speed.

  14. Pumping Performance or RBCC Engine under Sea Level Static Condition

    NASA Astrophysics Data System (ADS)

    Kouchi, Toshinori; Tomioka, Sadatake; Kanda, Takeshi

    Numerical simulations were conducted to predict the ejector pumping performance of a rocket-ramjet combined-cycle engine under a take-off condition. The numerical simulations revealed that the suction airflow was chocked at the exit of the engine throat when the ejector rocket was driven by cold N2 gas at the chamber pressure of 3MPa. When the ejector-driving gas was changed from cold N2 gas to hot combustion gas, the suction performance decreased remarkably. Mach contours in the engine revealed that the rocket plume constricted when the driving gas was the hot combustion gas. The change of the area of the stream tube area seemed to induce the pressure rise in the duct and decreasing in the pumping performance.

  15. Current fluctuations in periodically driven systems

    NASA Astrophysics Data System (ADS)

    Barato, Andre C.; Chetrite, Raphael

    2018-05-01

    Small nonequelibrium systems driven by an external periodic protocol can be described by Markov processes with time-periodic transition rates. In general, current fluctuations in such small systems are large and may play a crucial role. We develop a theoretical formalism to evaluate the rate of such large deviations in periodically driven systems. We show that the scaled cumulant generating function that characterizes current fluctuations is given by a maximal Floquet exponent. Comparing deterministic protocols with stochastic protocols, we show that, with respect to large deviations, systems driven by a stochastic protocol with an infinitely large number of jumps are equivalent to systems driven by deterministic protocols. Our results are illustrated with three case studies: a two-state model for a heat engine, a three-state model for a molecular pump, and a biased random walk with a time-periodic affinity.

  16. Experiments on pumping of liquids using arrays of microelectrodes subjected to travelling wave potentials

    NASA Astrophysics Data System (ADS)

    García-Sánchez, P.; Ramos, A.; Green, Nicolas G.; Morgan, H.

    2008-12-01

    Net fluid flow of electrolytes driven on an array of microelectrodes subjected to a travelling-wave potential is presented. Two sizes of platinum microelectrodes have been studied. In both arrays, at low voltages the liquid flows according to the prediction given by ac electroosmotic theory. At voltages above a threshold the fluid flow is reversed. Measurements of the electrical current when the microelectrode array is pumping the liquid are also reported. Transient behaviours in both electrical current and fluid velocity have been observed.

  17. Impact of anatase and rutile titanium dioxide nanoparticles on uptake carriers and efflux pumps in Caco-2 gut epithelial cells

    NASA Astrophysics Data System (ADS)

    Dorier, M.; Brun, E.; Veronesi, G.; Barreau, F.; Pernet-Gallay, K.; Desvergne, C.; Rabilloud, T.; Carapito, C.; Herlin-Boime, N.; Carrière, M.

    2015-04-01

    TiO2 microparticles are widely used in food products, where they are added as a white food colouring agent. This food additive contains a significant amount of nanoscale particles; still the impact of TiO2 nanoparticles (TiO2-NPs) on gut cells is poorly documented. Our study aimed at evaluating the impact of rutile and anatase TiO2-NPs on the main functions of enterocytes, i.e. nutrient absorption driven by solute-liquid carriers (SLC transporters) and protection against other xenobiotics driven by efflux pumps from the ATP-binding cassette (ABC) family. We show that acute exposure of Caco-2 cells to both anatase (12 nm) and rutile (20 nm) TiO2-NPs induce early upregulation of a battery of efflux pumps and nutrient transporters. In addition they cause overproduction of reactive oxygen species and misbalance redox repair systems, without inducing cell mortality or DNA damage. Taken together, these data suggest that TiO2-NPs may increase the functionality of gut epithelial cells, particularly their property to form a protective barrier against exogenous toxicants and to absorb nutrients.TiO2 microparticles are widely used in food products, where they are added as a white food colouring agent. This food additive contains a significant amount of nanoscale particles; still the impact of TiO2 nanoparticles (TiO2-NPs) on gut cells is poorly documented. Our study aimed at evaluating the impact of rutile and anatase TiO2-NPs on the main functions of enterocytes, i.e. nutrient absorption driven by solute-liquid carriers (SLC transporters) and protection against other xenobiotics driven by efflux pumps from the ATP-binding cassette (ABC) family. We show that acute exposure of Caco-2 cells to both anatase (12 nm) and rutile (20 nm) TiO2-NPs induce early upregulation of a battery of efflux pumps and nutrient transporters. In addition they cause overproduction of reactive oxygen species and misbalance redox repair systems, without inducing cell mortality or DNA damage. Taken together, these data suggest that TiO2-NPs may increase the functionality of gut epithelial cells, particularly their property to form a protective barrier against exogenous toxicants and to absorb nutrients. Electronic supplementary information (ESI) available: Nanoparticle physico-chemical characterization: size distribution in exposure medium, as measured by DLS (Fig. S1), and X-ray diffraction patterns of A12 and R20 (Fig. S2); characterization of the protein corona on A12 and R20 (Table S1-S4 and experimental). See DOI: 10.1039/c5nr00505a

  18. INTERIOR OF BOILER BUILDING, FIRST LEVEL, EAST SIDE, SHOWING STEAMDRIVEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR OF BOILER BUILDING, FIRST LEVEL, EAST SIDE, SHOWING STEAM-DRIVEN PISTON PUMPS FOR FUEL OIL, CAMERA FACING EAST. - New Haven Rail Yard, Central Steam Plant and Oil Storage, Vicinity of Union Avenue, New Haven, New Haven County, CT

  19. KSC-06pd0840

    NASA Image and Video Library

    2006-05-17

    KENNEDY SPACE CENTER, FLA. -- The payload canister passes NASA's Vehicle Assembly Building and Launch Control Center on its way to Launch Pad 39B. Inside are the payloads for mission STS-121: the multi-purpose logistics module Leonardo, with supplies and equipment for the International Space Station; the lightweight multi-purpose experiment support structure carrier; and the integrated cargo carrier, with the mobile transporter reel assembly and a spare pump module. The payload will be transferred from the canister to Space Shuttle Discovery's payload bay at the pad. Discovery is scheduled to launch on mission STS-121 from Launch Pad 39B in a window that opens July 1 and extends to July 19. Photo credit: NASA/Kim Shiflett

  20. KSC-06pd0845

    NASA Image and Video Library

    2006-05-17

    KENNEDY SPACE CENTER, FLA. -- The payload canister passes NASA's Vehicle Assembly Building and Launch Control Center on its way to Launch Pad 39B. Inside are the payloads for mission STS-121: the multi-purpose logistics module Leonardo, with supplies and equipment for the International Space Station; the lightweight multi-purpose experiment support structure carrier; and the integrated cargo carrier, with the mobile transporter reel assembly and a spare pump module. The payload will be transferred from the canister to Space Shuttle Discovery's payload bay at the pad. Discovery is scheduled to launch on mission STS-121 from Launch Pad 39B in a window that opens July 1 and extends to July 19. Photo credit: NASA/Troy Cryder

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