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Sample records for du transport actif

  1. Modélisation du transportactif en milieu poreux : schéma itératif associé à une combinaison d'éléments finis discontinus et mixtes-hybridesModelling reactive transport in porous media: iterative scheme and combination of discontinuous and mixed-hybrid finite elements

    NASA Astrophysics Data System (ADS)

    Carrayrou, Jérôme; Mosé, Robert; Behra, Philippe

    2003-03-01

    The sequential iterative approach (SIA) scheme is the most efficient method for modelling reactive transport in porous media with the operator-splitting approach. A combination of finite discontinuous and finite mixed-hybrid elements is a powerful method for solving solute transport in porous media, but the use of this method for SIA scheme induces numerical difficulties. In this paper, a new method is developed to solve reactive transport by using both the SIA scheme and a combination of finite discontinuous and finite mixed elements. The proposed method is tested by modelling a column experiment. To cite this article: J. Carrayrou et al., C. R. Mecanique 331 (2003).

  2. Les noyaux actifs de galaxies

    NASA Astrophysics Data System (ADS)

    Camenzind, Max; Boucher, A.

    Découverts il y a plus de 30 ans, les quasars et les radiogalaxies sont des galaxies particulières qui manifestent en leur centre une activité intense. Cet ouvrage se consacre aux principales questions de la physique des noyaux actifs en les illustrant par de récentes données. Y sont traités les domaines suivants: les noyaux des galaxies actives, la théorie des trous noirs en rotation et de leurs disques d'accrétion, l'origine des raies d'émission et les jets des galaxies actives. Fournissant une introduction génerale à la terminologie, cet ouvrage s'adresse aussi bien aux étudiants en astronomie qu'aux astrophysiciens.

  3. Dysfonctionnements radio-induits du transport colique chez le rat

    NASA Astrophysics Data System (ADS)

    François, A.; Lebrun, F.; Ksas, B.; Aigueperse, J.; Gourmelon, P.; MacNaughton, W. K.; Griffiths, N. M.

    1998-04-01

    The symptom commonly associated with whole body irradiation is diarrhoea, a still quite obscure phenomenon, which leads to decreased chance of cure of irradiated people. The aim of this study was to provide evidence for dysfunction of intestinal water and electrolyte transport regulation by the enteric nervous system after exposure to ionising radiation. This study shows decreased capacity of enteric nervous system to influence colonic transport 3days after irradiation, correlated to a diminished response to a neurotransmitter: serotonin. Radio-induced diarrhea may result from epithelial structural injury but also from impaired regulatory processes of intestinal transport. L'un des symptômes majeurs d'une irradiation corporelle totale ou abdominale est l'apparition de diarrhées, dont les causes sont encore mal connues, et qui mettent en jeu le pronostique vital de l'individu irradié. Cette étude vise à mettre en évidence l'atteinte de la régulation du transport intestinal d'eau et d'électrolytes par les rayonnements ionisants. On observe une diminution de la capacité du système nerveux entérique à influencer le transport colique 3jours après irradiation, corrélée à une diminution de la réponse épithéliale à un neurotransmetteur : la sérotonine. Les diarrhées radio-induites résulteraient d'une atteinte structurelle de l'épithélium mais également des processus de régulation du transport intestinal.

  4. Conception d'un controleur actif pour le retard de la transition de l'ecoulement laminaire au turbulent sur une aile a geometrie du profil variable dans le tunnel a vent

    NASA Astrophysics Data System (ADS)

    Popov, Andrei Vladimir

    The aerospace industry is motivated to reduce fuel consumption in large transport aircraft, mainly through drag reduction. The main objective of the global project is the development of an active control system of wing airfoil geometry during flight in order to allow drag reduction. Drag reduction on a wing can be achieved through modifications in the laminar-to-turbulent flow transition point position, which should be situated as close as possible to the trailing edge of the airfoil wing. As the transition point plays a crucial part in this project, this work focuses on the control of its position on the airfoil, as an effect of controlling the deflection of a morphing wing airfoil equipped with a flexible skin. The paper presents the modeling and the experimental testing of the aerodynamic performance of a morphing wing, starting from the design concept phase all the way to the bench and wind tunnel tests phases. Several wind tunnel test runs for various Mach numbers and angles of attack were performed in the 6 x 9 ft2 wind tunnel at the Institute for Aerospace Research at the National Research Council Canada. A rectangular finite aspect ratio wing, having a morphing airfoil cross-section due to a flexible skin installed on the upper surface of the wing, was instrumented with Kulite transducers. The Mach number varied from 0.2 to 0.3 and the angle of attack between -1° and 2°. Unsteady pressure signals were recorded and analyzed and a thorough comparison, in terms of mean pressure coefficients and their standard deviations, was performed against theoretical predictions, using the XFoil computational fluid dynamics code. The acquired pressure data was analyzed through custom-made software created with Matlab/Simulink in order to detect the noise magnitude in the surface airflow and to localize the transition point position on the wing upper surface. This signal processing was necessary in order to detect the Tollmien-Schlichting waves responsible for triggering

  5. Filtrage actif des harmoniques en courant et en tension des reseaux électriques : modélisation, simulation numérique et expérimentation

    NASA Astrophysics Data System (ADS)

    Lott, C.; Lapierre, O.; Pouliquen, H.; Saadate, S.

    1997-12-01

    Static converters generate harmonic currents and consume reactive power. These new phenomena on the mains generate some perturbations going from malfunction to destruction of the connected sensible equipments. In this paper disturbances generated by static converters are studied. Some solutions based on passive and active filtering are presented. Some passive filter design elements are given. Active filter is then studied. Both structures, current and voltage, are studied and voltage source structure is chosen. Different active filter control principles are presented. The active and reactive instantaneous power theory give good results for harmonic identification. Some numerical simulation are realized. A 100kVA prototype is realized and tested on an industrial site. The GTO prototype shows good results for harmonic filtering. The voltage active filtering is also presented. The active filter eliminates voltage harmonics on 400 V busbar generated by a MVA SCR bridge connected on 15kV busbar. Les convertisseurs statiques absorbent des courants non sinusoïdidaux et consomment généralement de la puissance réactive. Ces deux phénomènes nouveaux sur le réseau ont engendré un certain nombre de perturbations allant du dysfonctionnement d'un équipement jusqu'à la destruction d'une partie des équipements connectés. Dans cet article, les problèmes liés aux perturbations générées par les convertisseurs statiques ont été étudiés et des solutions visant à les éliminer ont été présentées. Elles portent sur les méthodes de filtrage passif et actif. Quelques éléments de définition et de dimensionnement de filtres passifs sont donnés. Le filtrage actif est ensuite traité. Les deux structures, courant et tension, sont étudiées et la structure tension a été retenue pour la suite de l'article. Différents principes de contrôle du filtre actif à structure tension ont été présentés. La méthode d'identification des harmoniques par le principe du

  6. Katimavik Participant's Manual, Book IX, Active Leisure = Katimavik manuel du participant, cahier IX, loisirs actifs.

    ERIC Educational Resources Information Center

    Crelinsten, Michael, Ed.

    The bilingual student manual, devoted to the active leisure learning activity portion of Katimavik (the nine-month volunteer community service and experiential learning program for 17 to 21 year old Canadians) contains sections on learning program objectives and trimester guidelines; optional activities; resume recordkeeping; general information…

  7. Les accidents du travail dans le transport urbain en commun de la ville province de Kinshasa, République Démocratique du Congo: une étude transversale descriptive

    PubMed Central

    Wangata, Jemima; Elenge, Myriam; De Brouwer, Christophe

    2014-01-01

    Introduction Le transport en commun urbain constitue un secteur où les travailleurs sont très exposés aux accidents du travail. Cette étude visait une description épidémiologique des accidents du travail dans le secteur informel du transport en commun à Kinshasa en vue d'apporter les pistes d'amélioration de la sécurité des travailleurs dans cette activité. Méthodes Un questionnaire sur les accidents du travail, administré en Décembre 2012 a permis d'explorer les tendances significatives entre les accidents et leurs circonstances, leurs facteurs associés, leurs conséquences au sein d'une population des travailleurs (n = 472) du transport en commun à Kinshasa. Résultats Durant les 12 derniers précédant l’étude 76.5% des travailleurs ont connu au moins un accident du travail, 54,8% ont connu un arrêt d'au moins 1jour. Les accidents liés à la circulation routière étaient plus important suivis des chutes. Les facteurs ayant montré des différences significatives étaient le travail sous l'influence de l'alcool et le port des équipements de protection individuelle. Les plaies (46,3%) et les contusions (39,4%) étaient les lésions les plus courantes. Les membres supérieurs (51,3%) et inférieurs (30,7%) étaient les plus atteints. 76,6% des travailleurs ont assumé seuls leur prise en charge médicale. Conclusion L'incidence des accidents du travail dans ce secteur est très élevée. La mise en place d'une politique de prévention et gestion de différents facteurs associés ainsi qu'un système de déclaration d'accidents est nécessaire dans ce secteur. Les patrons ainsi que les politiques devraient veiller à une prise en charge médicale correcte pour des travailleurs accidentés. PMID:25667703

  8. Étude de l'élimination de bleu de méthylène dans l'eau par le charbon actif commercial CECA40

    NASA Astrophysics Data System (ADS)

    Houas, A.; Bakir, I.; Ksibi, M.; Elaloui, E.

    1999-03-01

    The removal of methylene blue(BM) through adsorption over the commercial actived charcoal ( CECA40) was studied in a static batch reactor. At constant pH and temperature the adsorption equilibrium time is equal to 5 hours regardless of the initial concentration of metylene blue (BM). The adsorption in this case follows a Langmuir isotherm of the first type with an ultimate adsorption capacity of about 367,6mg of methylene blue for each gram of CECA40. Moreover, we observed no significant influence of temperature on the adsorption equilibrium. The adsorption and the Intraparticular diffusion kinectics were studied. Adsorption is clearly higher in an alcaline environment than in the acid one. This adsorption is further improved by the use of finer granulometry. L'élimination du bleu de méthylène (BM) en solution aqueuse par adsorption sur le charbon actif commercial CECA 40 a été étudiée en réacteur statique clos. A pH et Température constants, le temps d'équilibre d'adsorption est indépendant de la concentration initiale du bleu de méthylène et égal à 5 heures. L'adsorption de ce colorant obéit à une isotherme de Langmuir de type I avec une capacité ultime d'adsorption de l'ordre de 367,6 mg de BM par gramme de CECA40. On note également l'absence d'effet important de la température sur l'équilibre d'adsorption. Les cinétiques d'adsorption et de diffusion intraparticulaire ont été étudiées L'adsorption est nettement meilleure en milieu basique qu'en milieu acide .Elle est meilleure, également, pour la granulométrie la plus fine.

  9. Comparison of inhibitory potency by nonpeptide angiotensin II receptor antagonists PD123177 and DuP 753 on proximal nephron and renal transport.

    PubMed

    Cogan, M G; Liu, F Y; Wong, P C; Timmermans, P B

    1991-11-01

    The nonpeptide angiotensin II receptor antagonists, DuP 753 and PD123177, have been recently proposed to efficiently discriminate between two receptor subtypes. Because angiotensin II uses two signaling systems to control transport in the proximal tubule, the hypothesis was entertained that angiotensin-regulated proximal reabsorption might be transduced through two receptor subtypes and, therefore, have two components, sensitive to either DuP 753 or PD123177. Using in vivo microperfusion in the rat, a maximally effective dose of PD123177 (60 or 120 mg/kg, i.v.) had a powerful inhibitory effect on transport in the S1 proximal tubule, significantly (P less than .001) reducing bicarbonate absorption by 50% (360 +/- 4 to 179 +/- 8 peq/mm.min), chloride absorption by 38% (211 +/- 1 to 131 +/- 4 peq/mm.min) and sodium and water absorption by 32% (5.7 +/- 0.1 to 3.9 +/- 0.5 nl/mm.min). These results were only slightly different than previously reported effects on proximal solute and water absorption by DuP 753 (10 mg/kg). The two drugs demonstrated virtually no additivity in their transport inhibitory effects. Although downstream reabsorptive elements compensate for the powerful action of PD123177 in the earliest segment of the nephron, we also showed, using free-flow micropuncture and clearance techniques, that PD123177 induces a substantial diuresis, natriuresis and chloruresis, again similar in magnitude to DuP 753. These results suggest PD123177 has diuretic potency roughly equivalent to that of DuP 753, but do not lend support to the simple thesis that there are two separately acting receptor-signal transduction systems in the proximal tubule for angiotensin II.

  10. Transport du cuivre à travers un film mince d'or protecteur

    NASA Astrophysics Data System (ADS)

    Gillet, M.; Guglielmacci, J. M.; Benhenda, S.; Pech, T.

    Thin gold films were deposited by "sputtering" onto thick copper substrate. The crystalline structure and topography of the deposits were investigated by scanning and transmission electron microscopy. A scanning Auger microanalysis was performed on the surface and in depth on the gold deposit before and after heating. The observations reveal that the copper arrives at the gold surface especially via holes. The transport rate of the copper via theses holes is very fast compared to the diffusion via grain boundaries. The origin of the holes is discussed: they result of strains due to the gold epitaxial growth on copper grains.

  11. Modelisation par elements finis du muscle strie

    NASA Astrophysics Data System (ADS)

    Leonard, Mathieu

    Ce present projet de recherche a permis. de creer un modele par elements finis du muscle strie humain dans le but d'etudier les mecanismes engendrant les lesions musculaires traumatiques. Ce modele constitue une plate-forme numerique capable de discerner l'influence des proprietes mecaniques des fascias et de la cellule musculaire sur le comportement dynamique du muscle lors d'une contraction excentrique, notamment le module de Young et le module de cisaillement de la couche de tissu conjonctif, l'orientation des fibres de collagene de cette membrane et le coefficient de poisson du muscle. La caracterisation experimentale in vitro de ces parametres pour des vitesses de deformation elevees a partir de muscles stries humains actifs est essentielle pour l'etude de lesions musculaires traumatiques. Le modele numerique developpe est capable de modeliser la contraction musculaire comme une transition de phase de la cellule musculaire par un changement de raideur et de volume a l'aide des lois de comportement de materiau predefinies dans le logiciel LS-DYNA (v971, Livermore Software Technology Corporation, Livermore, CA, USA). Le present projet de recherche introduit donc un phenomene physiologique qui pourrait expliquer des blessures musculaires courantes (crampes, courbatures, claquages, etc.), mais aussi des maladies ou desordres touchant le tissu conjonctif comme les collagenoses et la dystrophie musculaire. La predominance de blessures musculaires lors de contractions excentriques est egalement exposee. Le modele developpe dans ce projet de recherche met ainsi a l'avant-scene le concept de transition de phase ouvrant la porte au developpement de nouvelles technologies pour l'activation musculaire chez les personnes atteintes de paraplegie ou de muscles artificiels compacts pour l'elaboration de protheses ou d'exosquelettes. Mots-cles Muscle strie, lesion musculaire, fascia, contraction excentrique, modele par elements finis, transition de phase

  12. Optimisation des conditions de fonctionnement d'un pilote plasma de 25kW pour la purification du silicium

    NASA Astrophysics Data System (ADS)

    Erin, J.; Morvan, D.; Amouroux, J.

    1995-05-01

    The development of the silicon purification process by melting under reactive thermal plasma, in progress to industrial transfer (100 kW level), requires to take into account the best energetic conditions to achieve a material with good photovoltaic properties. This study concerns the energy balance of a plasma pilot at 25 kW. the results point out the effect of gas composition (Ar or Ar-H{2}) and gas injection mode in the plasma torch (single or double flow) on the energy conversion and melting rate. Le développement du procédé de purification du silicium par fusion sous plasma thermique réactif, en cours de transfert industriel, exige de fixer les conditions énergétiques optimales de fonctionnement tout en respectant l'objectif qui consiste à élaborer un matériau présentant les meilleures photovoltaïques. L'étude présentée concerne les bilans énergétiques d'un pilote plasma de 25 kW. Les résultats soulignent le rôle de la composition du mélange plasmagène (Ar ou Ar-H{2}) et du mode d'injection des gaz dans l'applicateur plasma (simple ou double flux) vis à vis du rendement énergétique et de la vitesse de fusion.

  13. Reconstruction de la surface de Fermi dans l'etat normal d'un supraconducteur a haute Tc: Une etude du transport electrique en champ magnetique intense

    NASA Astrophysics Data System (ADS)

    Le Boeuf, David

    Des mesures de resistance longitudinale et de resistance de Hall en champ magnetique intense transverse (perpendiculaire aux plans CuO2) ont ete effectuees au sein de monocristaux de YBa2Cu3Oy (YBCO) demacles, ordonnes et de grande purete, afin d'etudier l'etat fondamental des supraconducteurs a haute Tc dans le regime sous-dope. Cette etude a ete realisee en fonction du dopage et de l'orientation du courant d'excitation J par rapport a l'axe orthorhombique b de la structure cristalline. Les mesures en champ magnetique intense revelent par suppression de la supraconductivite des oscillations magnetiques des resistances longitudinale et de Hall dans YBa2Cu 3O6.51 et YBa2Cu4O8. La conformite du comportement de ces oscillations quantiques au formalisme de Lifshitz-Kosevich, apporte la preuve de l'existence d'une surface de Fermi fermee a caractere quasi-2D, abritant des quasiparticules coherentes respectant la statistique de Fermi-Dirac, dans la phase pseudogap d'YBCO. La faible frequence des oscillations quantiques, combinee avec l'etude de la partie monotone de la resistance de Hall en fonction de la temperature indique que la surface de Fermi d'YBCO sous-dope comprend une petite poche de Fermi occupee par des porteurs de charge negative. Cette particularite de la surface de Fermi dans le regime sous-dope incompatible avec les calculs de structure de bande est en fort contraste avec la structure electronique presente dans le regime surdope. Cette observation implique ainsi l'existence d'un point critique quantique dans le diagramme de phase d'YBCO, au voisinage duquel la surface de Fermi doit subir une reconstruction induite par l'etablissement d'une brisure de la symetrie de translation du reseau cristallin sous-jacent. Enfin, l'etude en fonction du dopage de la resistance de Hall et de la resistance longitudinale en champ magnetique intense suggere qu'un ordre du type onde de densite (DW) est responsable de la reconstruction de la surface de Fermi. L'analogie de

  14. Modèle d'aide à la gestion des eaux souterraines (MAGES). 2. Validation numérique du modèle de transport

    NASA Astrophysics Data System (ADS)

    Porel, Gilles; Delay, Frédérick; Banton, Olivier

    1998-11-01

    MAGES is a software developed at INRS-Eau (Canada) for forecasting pollution hazards in groundwater. The transport model uses stationary truncated temporal moment equations instead of the classical time dependent advection-dispersion equation. The aim of this work is to propose a numerical validation of the method by comparison with both analytical solutions in homogeneous medium and a sophisticated lagrangian model of transport in heterogeneous medium. It is shown that the temporal moment equations perform well, while saving on computation. This gives MAGES some abilities in water management problems which compensate for the poor knowledge of the transport parameters through numerous stochastic simulations.

  15. "Cirque du Freak."

    ERIC Educational Resources Information Center

    Rivett, Miriam

    2002-01-01

    Considers the marketing strategies that underpin the success of the "Cirque du Freak" series. Describes how "Cirque du Freak" is an account of events in the life of schoolboy Darren Shan. Notes that it is another reworking of the vampire narrative, a sub-genre of horror writing that has proved highly popular with both adult and child readers. (SG)

  16. Transportation.

    ERIC Educational Resources Information Center

    Crank, Ron

    This instructional unit is one of 10 developed by students on various energy-related areas that deals specifically with transportation and energy use. Its objective is for the student to be able to discuss the implication of energy usage as it applies to the area of transportation. Some topics covered are efficiencies of various transportation…

  17. Modèle multi-échelle du transport de fluide dans un milieu poreux chargé avec échanges cationiques : application aux tissus osseux

    NASA Astrophysics Data System (ADS)

    Kaiser, Joanna; Lemaire, Thibault; Naili, Salah; Sansalone, Vittorio

    2009-11-01

    To better understand the bone diseases, many models of porous cortical bone have been developed to simulate its in vivo behaviour. Thus we proposed multiscale models including multiphysical phenomena governing the hydraulic response of bone. However, all these models neglected the possible ionic exchanges at the cellular level. Since such chemical reactions directly change the physico-chemical properties of the tissue, the interstitial flow is also modified. The aim of this study is so to include these ionic exchanges in the bone fluid transport description by deriving their consequences at the macroscale. To cite this article: J. Kaiser et al., C. R. Mecanique 337 (2009).

  18. Reactive transport modeling of uranium 238 and radium 226 in groundwater of the Königstein uranium mine, Germany

    NASA Astrophysics Data System (ADS)

    Nitzsche, O.; Merkel, B.

    prises en compte pour obtenir des prédictions fiables concernant le transport des nucléides primaires dans les eaux souterraines. Ce papier montre la nécessité d'établir des stratégies de réhabilitation avant la fermeture de la mine d'uranium de Knigstein, près de Dresde (Allemagne). Des expériences de lessivage en colonne sur des carottes avec de l'eau enrichie en uranium fournissent des données sur le comportement de l'échange de l'uranium. La restitution de l'uranium a été observée après un lessivage par un volume supérieur à 20 fois celui des pores. Ce fort retard est dûà l'échange d'ions uranium positifs. Le code TReAC est un code de transportactif en 1D, 2D et 3D, qui a été modifié pour prendre en compte la décroissance radioactive de l'uranium et les principaux nucléides descendants, et pour introduire l'écoulement dans un milieu à double porosité. TReAC a simulé de façon satisfaisante les courbes de restitution des expériences sur colonne et a fourni une première approche des paramètres de l'échange. L'écoulement souterrain dans la région de la mine de Knigstein a été simulé au moyen du code FLOWPATH. Le comportement du transportactif a été simulé avec TReAC en une dimension, le long d'un axe d'écoulement long de 6000 m. Les résultats montrent que la migration de l'uranium est relativement lente ; mais du fait de la décroissance radioactive de l'uranium, la concentration en radium le long de cet axe augmente. Les résultats sont très sensibles à l'influence de l'écoulement en milieu à double porosité.

  19. L’utilisation du prémélange de monensin chez les vaches laitières : un suivi simple et essentiel pour s’assurer d’une utilisation adéquate

    PubMed Central

    Dubuc, Jocelyn; Baril, Jean; DesCôteaux, Luc

    2009-01-01

    Le prémélange de monensin est utilisé fréquemment sur les fermes laitières canadiennes. L’ingrédient actif de ce produit est le monensin sodique. Bien que son utilisation chez les vaches laitières soit sécuritaire, des cas de surdose ont été rapportés à la suite de consommation de niveaux de monensin plus élevés que ceux recommandés. Un suivi hebdomadaire du pourcentage de matières grasses du réservoir de lait de la ferme devrait être fait de routine suite à la livraison d’aliment médicamenteux contenant du monensin pour détecter rapidement les situations de surdose. L’observation d’une baisse soudaine de la consommation volontaire de matière sèche et l’apparition de diarrhée dans un troupeau sont d’autres signes cliniques de surdose de monensin. Une détection rapide de ces cas permettra de corriger la situation. PMID:19721781

  20. Les enzymes de l'espace extra-cellulaire du stratum corneum.

    PubMed

    Forestier, J P

    1992-04-01

    Synopsis Bien que le stratum corneum soit composé de cellules 'mortes', il est le siège d'une activité métabolique très importante. Mais, contrairement à la plupart d'autres tissus, cette activité a la particularité d'étre extra-cellulaire. Elle est due à des enzymes excrétées par les Corps d'Odland avec les bicouches céramidiques. Ces enzymes sont des hydrolases, elles sont identiques ou très proches de celles des lysosomes. Les principales activités observées correspondent à une (ou des) glycosidase(s), une phospholipase, une sphingomyélinase, une phosphatase, une (ou des) estérase(s), des sulfatases, des protéases. Comme les hydrolases des lysosomes, elles semblent peu spécifiques. Ce pool enzymatique pourrait jouer plusieurs rôles fondamentaux, notamment: 1. La transformation des bicouches gluco-céramidiques en bicouches ceramidiques plus lipophiles; 2. L'élimination de la membrane plasmique, dont certains produits du catabolisme, comme les acides gras et les céramides, peuvent être intégrés aux bicouches céramidiques; 3. La diminution de la cohésion entre les cornéocytes; 4. La protection contre l'intrusion de corps étrangers. Comme tout système enzymatique, les hydrolases extra-cellulaires, sont certainement soumises à des régulations. Plusieurs de ces régulations sont envisagées. A partir de considérations d'enzymologie, le pH de la base du stratum corneum peut être estiméà environ 5. En cosmétologie, les enzymes du stratum corneum sont mises à contribution pour rendre actifs des précurseurs. L'étude des conséquences des modifications de l'activité enzymatique sur l'état de la peau pourrait constituer une future voie de recherche extrêmement prometteuse.

  1. Cri du Chat syndrome

    PubMed Central

    Cerruti Mainardi, Paola

    2006-01-01

    The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics, and severe psychomotor and mental retardation. Malformations, although not very frequent, may be present: cardiac, neurological and renal abnormalities, preauricular tags, syndactyly, hypospadias, and cryptorchidism. Molecular cytogenetic analysis has allowed a cytogenetic and phenotypic map of 5p to be defined, even if results from the studies reported up to now are not completely in agreement. Genotype-phenotype correlation studies showed a clinical and cytogenetic variability. The identification of phenotypic subsets associated with a specific size and type of deletion is of diagnostic and prognostic relevance. Specific growth and psychomotor development charts have been established. Two genes, Semaphorin F (SEMAF) and δ-catenin (CTNND2), which have been mapped to the "critical regions", are potentially involved in cerebral development and their deletion may be associated with mental retardation in CdCS patients. Deletion of the telomerase reverse transcriptase (hTERT) gene, localised to 5p15.33, could contribute to the phenotypic changes in CdCS. The critical regions were recently refined by using array comparative genomic hybridisation. The cat-like cry critical region was further narrowed using quantitative polymerase chain reaction (PCR) and three candidate genes were characterised in this region. The diagnosis is based on typical clinical manifestations. Karyotype analysis and, in doubtful cases, FISH analysis will confirm the diagnosis. There is no specific therapy for CdCS but early rehabilitative and educational interventions improve the prognosis and considerable progress has been made in

  2. L'Aventure du LHC

    SciTech Connect

    2010-06-11

    Cette présentation s’adressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problèmes sont apparus en cours de route. Tous ont été résolus grâce au dévouement et à l’engagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les réussites qui ont marqués ces 15 dernières années et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.

  3. Etude de l'affaiblissement du comportement mecanique du pergelisol du au rechauffement climatique

    NASA Astrophysics Data System (ADS)

    Buteau, Sylvie

    Le rechauffement climatique predit pour les prochaines decennies, aura des impacts majeurs sur le pergelisol qui sont tres peu documentes pour l'instant. La presente etude a pour but d'evaluer ces impacts sur les proprietes mecaniques du pergelisol et sa stabilite a long terme. Une nouvelle technique d'essai de penetration au cone a taux de deformation controle, a ete developpee pour caracteriser en place le pergelisol. Ces essais geotechniques et la mesure de differentes proprietes physiques ont ete effectues sur une butte de pergelisol au cours du printemps 2000. Le developpement et l'utilisation d'un modele geothermique 1D tenant compte de la thermodependance du comportement mecanique ont permis d'evaluer que les etendues de pergelisol chaud deviendraient instables a la suite d'un rechauffement de l'ordre de 5°C sur cent ans. En effet, la resistance mecanique du pergelisol diminuera alors rapidement jusqu'a 11,6 MPa, ce qui correspond a une perte relative de 98% de la resistance par rapport a un scenario sans rechauffement.

  4. L'Aventure du LHC

    ScienceCinema

    None

    2016-07-12

    Cette présentation s’adressera principalement aux personnes qui ont construit le LHC. La construction du LHC fut longue et difficile. De nombreux problèmes sont apparus en cours de route. Tous ont été résolus grâce au dévouement et à l’engagement du personnel et des collaborateurs. Je reviendrai sur les coups durs et les réussites qui ont marqués ces 15 dernières années et je vous montrerai combien cette machine, le fruit de vos efforts, est extraordinaire.

  5. Modèle d'aide à la gestion des eaux souterraines (MAGES). 1. Théorie du modèle numérique de transport des contaminants

    NASA Astrophysics Data System (ADS)

    Delay, Frédérick; Banton, Olivier; Porel, Gilles

    1998-08-01

    MAGES is software for forecasting pollution hazards of groundwater which is in the process of development at INRS-Eau (Canada). The main distinctive feature of the model is the use of stationary truncated temporal moment equations instead of the classical time dependent advection-dispersion equation to solve the transport of contaminants. The aim of this work is to describe the theory of truncated temporal moment equations and to show how the curves of the concentration versus time can be calculated from temporal moments. The discrete method used to solve the equations and its stability is also discussed.

  6. Distribution and partitioning of depleted uranium (DU) in soils at weapons test ranges - investigations combining the BCR extraction scheme and isotopic analysis.

    PubMed

    Oliver, Ian W; Graham, Margaret C; Mackenzie, Angus B; Ellam, Robert M; Farmer, John G

    2008-06-01

    Depleted uranium (DU) has become a soil contaminant of considerable concern in many combat zones and weapons-testing sites around the world, including locations in Europe, the Middle East and the USA, arising from its dispersion via the application of DU-bearing munitions. Once DU is released into the environment its mobility and bioavailability will, like that of other contaminants, largely depend on the type of associations it forms in soil and on the nature of the soil components to which it binds. In this study we used the BCR sequential extraction scheme to determine the partitioning of DU amongst soil fractions of texturally varying soils from locations affected by weapons-testing activities. Isotopic analyses (MC-ICP-MS and alpha-spectrometry) were performed to verify the presence of DU in whole soils and soil fractions and to determine any preferential partitioning of the contaminant. Results identified soil organic matter as being consistently the most important component in terms of DU retention, accounting for 30-100% of DU observed in the soils examined. However, at greater distances from known contamination points, DU was also found to be largely associated with the exchangeable fraction, suggesting that DU can be mobilised and transported by surface and near-surface water and does remain in an exchangeable (and thus potentially bioavailable) form in soils.

  7. Étude ethnobotanique des plantes utilisées dans le traitement du diabète dans la médecine traditionnelle de la région Maritime du Togo

    PubMed Central

    Holaly, Gbekley Efui; Simplice, Karou Damintoti; Charlemagne, Gnoula; Kodjovi, Agbodeka; Kokou, Anani; Tchadjobo, Tchacondo; Amegnona, Agbonon; Komlan, Batawila; Jacques, Simpore

    2015-01-01

    Introduction Les plantes constituent une grande source de principes actifs qui peuvent être utilisés pour traiter de nombreuses maladies, dont le diabète. L'objectif de cette étude était de recenser les plantes utilisées en médecine traditionnelle pour traiter le diabète dans la région Maritime du Togo. Méthodes De janvier 2013 à juin 2014, une enquête ethnobotanique a été réalisée auprès de 164 guérisseurs traditionnels dans la région Maritime par des interviews directes à l'aide d'un questionnaire semi structuré. Résultats Les données recueillies ont permis d'identifier 112 espèces végétales appartenant à 51 familles. Les familles les plus représentées ont été les Caesalpiniaceae / Fabaceae avec 9 espèces, suivie des Euphorbiaceae et des Compositae avec 8 espèces chacune. Les espèces les plus citées ont été Allium sativum, Alium cepa, Guilandina bonduc, Moringa oleifera et de Picralima nitida qui ont eu une valeur usuelle de 0,05. En termes de recettes, 132 recettes sont préparées à partir des 112 espèces de plantes. Les recettes à plantes uniques ont été au nombre de 78, tandis que 54 recettes sont obtenues par des associations de plantes. Les parties de plantes les plus utilisées ont été les feuilles suivies par les racines. La principale méthode de préparation reste la décoction. Conclusion La région maritime du Togo dispose d'une biodiversité floristique importante en matière de plantes antidiabétiques. Ces résultats constituent une bonne base de données pour le criblage biologique dans la recherche de molécules antidiabétiques à base des plantes. PMID:26309469

  8. Les Noyaux Actifs de Galaxies en interférométrie optique à très longue base - Projet 'OHANA

    NASA Astrophysics Data System (ADS)

    Woillez, Julien

    2003-12-01

    on the different adaptive optics systems. Then I present the 'OHANA beam combiner that is about to be used in the demonstration phase (phase II). This combiner is based on a new concept where the two interferometric outputs of a single mode coaxial combination are combined in a multiaxial scheme in order to obtain a single output, with only one coupler. The interferogram is then temporally coded and the photometry spatially. I present the ongoing developments of pahse II, namely a gaussian beam delay line and 2×300 m long single mode fibers, in J, H and K bands, used for the coherent transport.

  9. Modeling erosion and transport of depleted uranium, Yuma Proving Ground, Arizona

    SciTech Connect

    Ward, T.J.; Stevens, K.A.

    1994-06-01

    The high density, relative abundance, and metallic properties have made depleted uranium (DU) an obvious choice for high energy ballistic projectiles. The U.S. Army`s Yuma Proving Ground (YPG) in southwest Arizona tests DU projectiles. When DU projectiles strike a target or the downrange ground surface, they fragment. Most of the fragments are collected after the test firings, but some are either too small or too dispersed to be easily found. Unfortunately, DU has some undesirable characteristics, it is a radioactive material (alpha particle emitter) and a toxic metal. Therefore, the fragments not found pose a potential environmental hazard at the YPG and to surrounding areas. The U.S. Army has contracted with the Los Alamos National Laboratory (LANL) to study the fate of DU at the YPG. In turn, LANL has contracted with New Mexico State University (NMSU) to investigate water transport of DU during rainfall-runoff events. Nine simulation runs were made on YPG soil containing DU fragments from the impact areas. The nine simulations consisted of three groups of three: rainfall simulation only, overland flow only, and rainfall/overland flow combination. Infiltration rates in the DU ballistic impact areas at YPG were very close to zero. Larger concentrations of DU were contained in the impact area soil which was retained by the 1 mm and 0.5 mm sieves when grain-size analysis was performed. After all nine simulations were completed, a mass balance of the uranium showed most DU remained in the soil box even under extreme hydraulic conditions, though about 7% (by weight) did exit the box. No DU was found in the suspended sediment samples and this suggests that most transport of DU is restricted to contact or bed-load movement during overland flow. Because the experiments were conducted to simulate extreme rainfall-runoff conditions, the probability of significant transport of DU from land surface appears to be low.

  10. Les déterminants du statut “perdu de vue” chez les patients pris en charge pour cancer au Maroc: situation avant le Plan Cancer

    PubMed Central

    Najdi, Adil; Berraho, Mohamed; Bendahhou, Karima; Obtel, Majdouline; Zidouh, Ahmed; Errihani, Hassan; Nejjari, Chakib

    2014-01-01

    Introduction Le cancer au Maroc représente un problème majeur de santé publique, sa prise en charge doit être globale, active et complète pour tous les patients. L'objectif de ce travail était d'estimer la fréquence des perdus de vue « PDV » en oncologie au Maroc durant la première année de suivi et de déterminer les facteurs associés à ce problème. Méthodes Par une étude rétrospective portant sur 2854 dossiers de malades hospitalisés dans les trois principaux centres d'oncologie au Maroc depuis janvier 2003 jusqu’à juin 2007 et concernant les cinq principales localisations de cancer au Maroc, nous avons cherché la date des dernières nouvelles des patients ayant un recul de 18 mois minimum afin de déterminer le statut de ces malades après un an de suivi. Résultats La moyenne d’âge était de 52±14 ans, une proportion féminine de 63%, les sujets actifs constituaient 28%, les mariés 71%, les analphabètes 51%, 70% des patients habitaient en milieu urbain et seulement 11% des malades disposaient d'une couverture sociale. La localisation cancéreuse la plus fréquente était le poumon (23,8%) suivie du colon-rectum (23,5%) puis le col (21,9%), le sein (20,4%) et les lymphomes (10,4%). Le taux des «PDV» à un an de suivi était de 48%, ce statut était significativement lié au sexe, à l’âge, au NSE et au statut matrimonial. Sur le plan médical, le statut «PDV» était lié à la localisation du cancer, au stade de diagnostic et au type de traitement reçu. Conclusion Notre étude a mis en évidence la grande ampleur du problème des PDV en cancérologie au Maroc ainsi que ces déterminants. Ces résultats incitent tous les acteurs dans le domaine de la cancérologie à collaborer ensemble pour prendre les mesures qui s'imposent pour y pallier PMID:25400850

  11. Approche de prise en charge du trouble du spectre de l’autisme

    PubMed Central

    Lee, Patrick F.; Thomas, Roger E.; Lee, Patricia A.

    2015-01-01

    Résumé Objectif Se pencher sur les critères diagnostiques du trouble du spectre de l’autisme (TSA) comme les définit le Manuel diagnostique et statistique des troubles mentaux, cinquième édition (DSM-V), et concevoir une approche de prise en charge du TSA à l’aide du cadre CanMEDS–Médecine familiale (CanMEDS-MF). Sources d’information Le DSM-V, publié par l’American Psychiatric Association en mai 2013, énonce de nouveaux critères diagnostiques du TSA. Le cadre CanMEDS-MF du Collège des médecins de famille du Canada fournit un plan d’orientation pour la prise en charge complexe du TSA. Nous avons utilisé des données recueillies par le Centers for Disease Control and Prevention afin de déterminer la prévalence du TSA, ainsi que la revue systématique et méta-analyse détaillée effectuée par le National Institute for Health and Care Excellence du R.-U. pour ses lignes directrices sur le TSA dans le but d’évaluer les données probantes issues de plus de 100 interventions. Message principal Selon les données du Centers for Disease Control and Prevention, la prévalence du TSA se chiffrait à 1 sur 88 en 2008 aux États-Unis. La classification du TSA dans la quatrième édition du DSM incluait l’autisme, le syndrome d’Asperger, le trouble envahissant du développement et le trouble désintégratif de l’enfance. La dernière révision du DSM-V réunit tous ces troubles sous la mention TSA, avec différents niveaux de sévérité. La prise en charge du TSA est complexe; elle exige les efforts d’une équipe multidisciplinaire ainsi que des soins continus. Les rôles CanMEDS-MF fournissent un cadre de prise en charge. Conclusion Les médecins de famille sont au cœur de l’équipe de soins multidisciplinaire pour le TSA, et le cadre CanMEDS-MF tient lieu de plan détaillé pour guider la prise en charge d’un enfant atteint de TSA et aider la famille de cet enfant.

  12. Les plaies du tendon patellaire

    PubMed Central

    Mechchat, Atif; Elidrissi, Mohammed; Mardy, Abdelhak; Elayoubi, Abdelghni; Shimi, Mohammed; Elibrahimi, Abdelhalim; Elmrini, Abdelmajid

    2014-01-01

    Les plaies du tendon patellaire sont peu fréquentes et sont peu rapportés dans la littérature, contrairement aux ruptures sous cutanées. Les sections du tendon patellaire nécessitent une réparation immédiate afin de rétablir l'appareil extenseur et de permettre une récupération fonctionnelle précoce. A travers ce travail rétrospectif sur 13 cas, nous analysons les aspects épidémiologiques, thérapeutiques et pronostiques de ce type de pathologie en comparant différents scores. L’âge moyen est de 25 ans avec une prédominance masculine. Les étiologies sont dominées par les accidents de la voie publique (68%) et les agressions par agent tranchant (26%) et contendant (6 %). Tous nos patients ont bénéficié d'un parage chirurgical avec suture tendineuse direct protégée par un laçage au fils d'aciers en légère flexion. La rééducation est débutée après sédation des phénomènes inflammatoires. Au dernier recul les résultats sont excellents et bon à 92%. Nous n'avons pas noté de différence de force musculaire et d'amplitude articulaire entre le genou sain et le genou lésé. Les lésions ouvertes du tendon patellaire est relativement rare. La prise en charge chirurgicale rapide donne des résultats assez satisfaisants. La réparation est généralement renforcée par un semi-tendineux, synthétique ou métallique en forme de cadre de renfort pour faciliter la réadaptation et réduire le risque de récidive après la fin de l'immobilisation. PMID:25170379

  13. Learning about Cri du Chat Syndrome

    MedlinePlus

    ... chat syndrome - also known as 5p- syndrome and cat cry syndrome - is a rare genetic condition that ... du chat syndrome usually include a high-pitched cat-like cry, mental retardation, delayed development, distinctive facial ...

  14. Long-term corrosion and leaching of depleted uranium (DU) in soil.

    PubMed

    Schimmack, W; Gerstmann, U; Schultz, W; Geipel, G

    2007-08-01

    Corrosion and leaching of depleted uranium (DU) was investigated for 3 years using six DU munitions (145-264 g DU) each buried in a column with a soil core of about 3.3 kg dry soil mass. The columns were installed in an air-conditioned laboratory. Each week they were irrigated and (238)U was determined in the effluents by inductively coupled plasma mass spectrometry. In addition, (235)U was measured occasionally to assure that the (238)U was predominantly from the DU munition. On average, 14.5 g corresponding to 7.9% of the initial DU mass was corroded after 3 years, indicating an increased corrosion as compared to the first year of observation. The leaching rates increased much stronger than the corrosion rates by factors of more than 100, resulting in a mean total amount of leached (238)U of 13 mg as compared to 0.03 mg after the first year. Uranium species identified in the seepage water by time-resolved laser-induced fluorescence spectroscopy were mainly hydroxo and carbonate compounds, while those in the corroded material were phosphate compounds. It is concluded that the dramatic increase of the leaching and its large temporal variability do not allow any extrapolation for the future. However, the high (238)U concentrations observed in the seepage water highlight the need for further investigations on the transport of (238)U through soil, in particular with regard to the potential future (238)U contamination of groundwater in areas affected by DU weapons. PMID:17549506

  15. Long-term corrosion and leaching of depleted uranium (DU) in soil.

    PubMed

    Schimmack, W; Gerstmann, U; Schultz, W; Geipel, G

    2007-08-01

    Corrosion and leaching of depleted uranium (DU) was investigated for 3 years using six DU munitions (145-264 g DU) each buried in a column with a soil core of about 3.3 kg dry soil mass. The columns were installed in an air-conditioned laboratory. Each week they were irrigated and (238)U was determined in the effluents by inductively coupled plasma mass spectrometry. In addition, (235)U was measured occasionally to assure that the (238)U was predominantly from the DU munition. On average, 14.5 g corresponding to 7.9% of the initial DU mass was corroded after 3 years, indicating an increased corrosion as compared to the first year of observation. The leaching rates increased much stronger than the corrosion rates by factors of more than 100, resulting in a mean total amount of leached (238)U of 13 mg as compared to 0.03 mg after the first year. Uranium species identified in the seepage water by time-resolved laser-induced fluorescence spectroscopy were mainly hydroxo and carbonate compounds, while those in the corroded material were phosphate compounds. It is concluded that the dramatic increase of the leaching and its large temporal variability do not allow any extrapolation for the future. However, the high (238)U concentrations observed in the seepage water highlight the need for further investigations on the transport of (238)U through soil, in particular with regard to the potential future (238)U contamination of groundwater in areas affected by DU weapons.

  16. Pru du 2S albumin or Pru du vicilin?

    PubMed

    Garino, Cristiano; De Paolis, Angelo; Coïsson, Jean Daniel; Arlorio, Marco

    2015-06-01

    A short partial sequence of 28 amino acids is all the information we have so far about the putative allergen 2S albumin from almond. The aim of this work was to analyze this information using mainly bioinformatics tools, in order to verify its rightness. Based on the results reported in the paper describing this allergen from almond, we analyzed the original data of amino acids sequencing through available software. The degree of homology of the almond 12kDa protein with any other known 2S albumin appears to be much lower than the one reported in the paper that firstly described it. In a publicly available cDNA library we discovered an expressed sequence tag which translation generates a protein that perfectly matches both of the sequencing outputs described in the same paper. A further analysis indicated that the latter protein seems to belong to the vicilin superfamily rather than to the prolamin one. The fact that also vicilins are seed storage proteins known to be highly allergenic would explain the IgE reactivity originally observed. Based on our observations we suggest that the IgE reactive 12kDa protein from almond currently known as Pru du 2S albumin is in reality the cleaved N-terminal region of a 7S vicilin like protein.

  17. Biokinetics and dosimetry of depleted uranium (DU) in rats implanted with DU fragments.

    SciTech Connect

    Guilmette, Ray A.; Hahn, Fletcher F.; Durbin, P. W.

    2004-01-01

    A number of U. S. veterans of the Persian Gulf War were wounded with depleted uranium (DU) metal fragments as a result of 'friendly fire' incidents, in which Abrams tanks and Bradley fighting vehicles were struck by DU anti-armor munitions. Some of the crew members who survived were left with multiple small fragments of DU in their muscles and soft tissues. The number, size and location of the fragments made them inoperable in general, and therefore subject to long-term retention. Because there was inadequate data to predict the potential carcinogenicity of DU fragments in soft tissues, Hahn et al. (2003) conducted a lifespan cancer study in rats. As part of that study, a number of rats were maintained to study the biokinetics and dosimetry of DU implanted intramuscularly in male Wistar rats. Typically, four metal fragments, either as cylindrical pellets or square wafers were implanted into the biceps femoris muscles of the rats. Urine samples were collected periodically during their lifespans, and DU was analyzed in kidneys and eviscerated carcass (minus the implant sites) at death. The daily DU urinary excretion rate increased steeply during the first 30 d after implantation peaking at about 90 d at 3-10 x 10{sup -3}%/d. During the first 150 d, the average excretion rate was 2.4 x 10{sup -3}%/d, decreasing thereafter to about 1 x 10{sup -3}%/d. Serial radiographs were made of the wound sites to monitor gross morphologic changes in the DU implant and the surrounding tissue. As early as 1 w after implantation, radiographs showed the presence of surface corrosion and small, dense bodies near the original implant, presumably DU. This corrosion from the surface of the implant continued with time, but did not result in an increasing amount of DU reaching the blood and urine after the first 3 mo. During this 3-mo period, connective tissue capsules formed around the implants, and are hypothesized to have reduced the access of DU to tissue fluids by limiting the diffusion

  18. Résultats du traitement du synovialosarcome des members

    PubMed Central

    Lukulunga, Loubet Unyendje; Moussa, Abdou Kadri; Mahfoud, Mustapha; El Bardouni, Ahmed; Ismail, Farid; Kharmaz, Mohammed; Berrada, Mohamed Saleh; El Yaacoubi, Moradh

    2014-01-01

    Les synovialosarcomes, sarcomes de haut grade, sont de diagnostic tardif et le traitement est complexe et onéreux, nécessitant la mise en œuvre d'une équipe pluridisciplinaire. Le but de ce travail était d'apprécier les résultats de l'association de la chirurgie à la radio chimiothérapie des synovialosarcomes des membres. Il s'agissait d'une étude rétrospective portant sur des patients présentant de synovialosarcomes des membres pris en charge dans le service de chirurgie orthopédique et traumatologique du CHU Ibn SINA de Rabat allant de Janvier 2006 à Décembre 2011 (6 ans). Nous avons inclus les malades présentant de synovialosarcomes des membres dont la clinique et l'imagerie médicale étaient en faveur, confirmés par l'examen anatomopathologique et la prise en charge effectuée dans le service. Les patients ont été revus avec un recul moyen de 3 ans. Nous n'avons pas retenu les patients dont les dossiers étaient incomplets, perdus de vue. Nous avons apprécié les résultats selon les critères carcinologiques et le score MSTS (Musculoskeletal Tumor Society). La saisie et l'analyse des données ont été faites sur le logiciel SPSS Stastic 17.0 Nous avons colligé 20 cas de synovialosarcome des membres dans le Service de Chirurgie Orthopédique et Traumatologique au CHU Ibn SINA de Rabat Le sexe masculin a prédominé avec 65% (n = 13) avec un sex ratio 1,85. L’âge moyen a été de 42,6 ans avec des extrêmes allant de 20 ans et 70 ans. Notre délai moyen de consultation était de 14,42 mois. Tous les malades ont consulté pour une tuméfaction dans 100% (localisée au membre inférieur dans 65% (n = 13), membre supérieur dans 35% (n = 7). La douleur était associée à la tuméfaction dans 55% (n = 11), quant à l'altération de l’état général et l'ulcération de la masse, elles ont été notées dans 3 cas chacune. Nous avons réalisé un bilan d'imagerie médicale comprenant: radiographie standard, échographie, écho doppler

  19. Cirque du Monde as a health intervention

    PubMed Central

    Fournier, Cynthia; Drouin, Mélodie-Anne; Marcoux, Jérémie; Garel, Patricia; Bochud, Emmanuel; Théberge, Julie; Aubertin, Patrice; Favreau, Gil; Fleet, Richard

    2014-01-01

    Abstract Objective To present Cirque du Soleil’s social circus program, Cirque du Monde, to explore its potential as a primary health care tool for family physicians. Data sources A review of the literature in PubMed, the Cochrane Library, PsycINFO, LaPresse, Eureka, Google Scholar, and Érudit using the key words circus, social circus, Cirque du Monde, and Cirque du Soleil; a Montreal-based initiative, Espace Transition, modeled on Cirque du Monde; and personal communication with Cirque du Soleil’s Social Circus Training Advisor. Study selection The first 50 articles or websites identified for each key word in each of the databases were examined on the basis of their titles and abstracts in the case of articles, and on the basis of their titles and page content in the case of websites. Articles and websites that explored an aspect of social circuses or that described an intervention that involved circuses were then retained for analysis. Because all literature on social circuses was searched, no criterion for year of publication was used. Synthesis No articles on the social circus as a health intervention were found. One study on the use of the circus as an intervention in schools was identified. It demonstrated an increase in self-esteem in the children who took part. One study on the use of the circus in a First Nations community was found; it contained nonspecific, qualitative findings. The other articles identified were merely descriptions of social circuses. One website was identified on the use of the social circus to help youth who had been treated in a hospital setting for major psychiatric disorders to re-enter the community. The team in the pediatric psychiatry department at Centre Hospitalier Universitaire Sainte-Justine, the children’s hospital in Montreal, Que, was contacted; they were leading this project, called Espace Transition. The unpublished preliminary findings of its pilot project demonstrate substantial improvements in overall patient

  20. Unilateral hyperhydrosis in Pourfour du Petit syndrome.

    PubMed

    Kara, Murat; Dikmen, Erkan; Akarsu, Cengiz; Birol, Ahu

    2004-08-01

    Upper limp hyperhydrosis is an idiopathic disease with bilateral involvement. However, Pourfour du Petit syndrome, the opposite of Horner syndrome, may result in unilateral upper limb hyperhydrosis. It occurs following hyperactivity of the sympathetic cervical chain as a consequence of irritation secondary to trauma. We report herein two cases with Pourfour du Petit syndrome showing unilateral upper limb hyperhydrosis. The patients presented with right-sided mydriasis and ipsilateral hemifacial hyperhydrosis. The onset of disease was followed by a trauma in both patients. They underwent upper thoracic sympathectomy with favorable outcome. A history of an antecedent trauma in patients with unilateral upper limb hyperhydrosis and anisocoria may imply a possible diagnosis of Pourfour du Petit syndrome. PMID:15296919

  1. Processus mis en jeu dans l'evolution morpho-dynamique de Roberts Bank (Delta du Fraser): Observation et modelisation hydrodynamiques et sedimentaires

    NASA Astrophysics Data System (ADS)

    Meule, Samuel

    Roberts Bank couvre le delta intertidal entre le bras principal du fleuve Fraser et la pointe du Cap Roberts en Colombie Britannique, Canada. Sous la pression du developpement urbain et la modification du regime sedimentaire, cette plage de sable fin est soumise a une erosion significative. L'identification des forces hydrodynamiques, leur importance et leur interaction permettent de determiner les zones de transport, et donc la stabilite de Roberts Bank. Deux periodes de mesures associees a des phases de modelisation de la houle et des courants ont ete effectuees lors de ce travail. La premiere periode de mesure, entre le 29 juin et le 8 juillet 2001, a permis l'identification de processus hydrodynamiques et sedimentaires associes aux forts courants de maree presents le long de Roberts Bank. La seconde phase de mesure, entre le 1er mars et le 26 mars 2002, a permis d'etudier les processus de remise en suspension associes a la houle. Des phases de modelisation ont ete menees a partir des connaissances acquises sur le terrain, afin d'affiner la comprehension des processus sedimentaires et notamment les interactions houle - courant - sediment. Les mecanismes, mis en evidence dans cette etude, participent au faconnage de Roberts Bank, contribuent a son erosion et a la mise en place de nouvelles structures sedimentaires. Les courants de flot de maree vont initier la creation de nuages de resuspension de sediment depuis le fond. En eau peu profonde, la composante " onshore" du courant de maree induit un transport a la cote, tandis qu'en eau plus profonde une faible composante " offshore" du courant peut favoriser un transport au large le long de la pente. Les chenaux, les dunes subaquatiques et les surfaces d'erosion affleurantes fournissent une rugosite de fond suffisante a la generation de turbulence et donc de nuages de sediment en suspension. Lors de la maree de jusant, les sediments resuspendus en eau peu profonde, sont transportes vers le large a partir d

  2. Sign Communication in Cri du Chat Syndrome

    ERIC Educational Resources Information Center

    Erlenkamp, Sonja; Kristoffersen, Kristian Emil

    2010-01-01

    This paper presents findings from a study on the use of sign supported Norwegian (SSN) in two individuals with Cri du chat syndrome (CCS). The study gives a first account of some selected aspects of production and intelligibility of SSN in CCS. Possible deviance in manual parameters, in particular inter- and/or intra-subject variation in the use…

  3. Prejudice: From Allport to DuBois.

    ERIC Educational Resources Information Center

    Gaines, Stanley O., Jr.; Reed, Edward S.

    1995-01-01

    Examines the differences between Gordon Allport's and W. E. B. DuBois's theories on the origins of prejudice and the impact of discrimination on the personality and social development of blacks. The article argues that prejudice is a historically developed process, not a universal feature of human psychology. Implications for U.S. race relations…

  4. Structural credit for depleted uranium used in transport casks

    SciTech Connect

    Salzbrenner, R.; Wellman, G.W.; Sorenson, K.B.; McConnell, P.

    1992-02-01

    Depleted uranium (DU) is used in high level radioactive waste transport containers as a gamma shield. The mechanical response of this material has generally not been included in calculations intended to assure that these casks will maintain their containment function during all normal use and accident conditions. If DU could be qualified as a structural component, the thickness of other materials (e.g. stainless steel) in the primary containment boundary could be reduced, thereby allowing a reduction in cask mass and/or an increase in payload capacity. This study was conducted to determine the mechanical behavior of a range of DU alloys in order to extend the limited set of mechanical properties reported in the literature. These mechanical properties were used as the basis for finite element calculations to quantify the potential for claiming structural credit for DU.

  5. Structural credit for depleted uranium used in transport casks

    SciTech Connect

    Salzbrenner, R.; Wellman, G.W.; Sorenson, K.B. ); McConnell, P. )

    1992-01-01

    Depleted uranium (DU) is used in high level radioactive waste transport containers as a gamma shield. The mechanical response of this material has generally not been included in calculations intended to assure that these casks will maintain their containment function during all normal use and accident conditions. If DU could be qualified as a structural component, the thickness of other materials (e.g. stainless steel) in the primary containment boundary could be reduced, thereby allowing a reduction in cask mass and/or an increase in payload capacity. This study was conducted to determine the mechanical behavior of a range of DU alloys in order to extend the limited set of mechanical properties reported in the literature. These mechanical properties were used as the basis for finite element calculations to quantify the potential for claiming structural credit for DU.

  6. DU-AGG pilot plant design study

    SciTech Connect

    Lessing, P.A.; Gillman, H.

    1996-07-01

    The Idaho National Engineering Laboratory (INEL) is developing new methods to produce high-density aggregate (artificial rock) primarily consisting of depleted uranium oxide. The objective is to develop a low-cost method whereby uranium oxide powder (UO[sub 2], U[sub 3]O[sub ]8, or UO[sub 3]) can be processed to produce high-density aggregate pieces (DU-AGG) having physical properties suitable for disposal in low-level radioactive disposal facilities or for use as a component of high-density concrete used as shielding for radioactive materials. A commercial company, G-M Systems, conducted a design study for a manufacturing pilot plant to process DU-AGG. The results of that study are included and summarized in this report. Also explained are design considerations, equipment capacities, the equipment list, system operation, layout of equipment in the plant, cost estimates, and the proposed plan and schedule.

  7. Mars' 1995 opposition from PIC du Midi

    NASA Astrophysics Data System (ADS)

    Erard, S.

    1997-03-01

    The last Martian apparition was observed from Pic du Midi between October 1994 and March 1995. Earth-based observation remains the only practicable way to perform continuous surveys of the planets, as opposed to orbital (HST) or space-borne observation. A good planetary site with limited demand for observational time like the 1-m telescope at Pic du Midi provides the optimal opportunity to monitor planetary activity, including atmospheric phenomena, surface variations, and polar caps recession. For instance, HST observations of Mars during this period, though yielding a much better spatial resolution, are limited to very few sessions and do not make it possible to monitor quick processes along a whole Martian season.

  8. Sustainable growth, the DuPont way.

    PubMed

    Holliday, C

    2001-09-01

    Like many manufacturers, DuPont traditionally has grown by making more and more "stuff." And its business growth has been proportional to the amount of raw materials and energy used--as well as the resulting waste and emissions from operations. Over the years, though, DuPont became aware that cheap supplies of nonrenewable resources wouldn't be endlessly available and that the earth's ecosystems couldn't indefinitely absorb the waste and emissions of production and consumption. Chad Holliday, chairman and CEO of DuPont, believes strongly in the challenge of sustainable growth and makes the business case for it: By using creativity and scientific knowledge effectively, he says, companies can provide strong returns for shareholders and grow their businesses--while also meeting the human needs of societies around the world and reducing the environmental footprint of their operations and products. In fact, a focus on sustainability can help identify new products, markets, partnerships, and intellectual property and lead to substantial business growth. Holliday describes how DuPont developed a three-pronged strategy to translate the concept of sustainability into nuts-and-bolts business practices. Focusing on integrated science, knowledge intensity, and productivity improvement, the strategy was accompanied by a new way to measure progress quantitatively. Sustainable growth should be viewed not as a program for stepped-up environmental performance but as a comprehensive way of doing business, one that delivers tremendous economic value and opens up new opportunities. Ultimately, companies will find that they can generate substantial business value through sustainability while both enhancing the quality of life around the world and protecting the environment.

  9. Sustainable growth, the DuPont way.

    PubMed

    Holliday, C

    2001-09-01

    Like many manufacturers, DuPont traditionally has grown by making more and more "stuff." And its business growth has been proportional to the amount of raw materials and energy used--as well as the resulting waste and emissions from operations. Over the years, though, DuPont became aware that cheap supplies of nonrenewable resources wouldn't be endlessly available and that the earth's ecosystems couldn't indefinitely absorb the waste and emissions of production and consumption. Chad Holliday, chairman and CEO of DuPont, believes strongly in the challenge of sustainable growth and makes the business case for it: By using creativity and scientific knowledge effectively, he says, companies can provide strong returns for shareholders and grow their businesses--while also meeting the human needs of societies around the world and reducing the environmental footprint of their operations and products. In fact, a focus on sustainability can help identify new products, markets, partnerships, and intellectual property and lead to substantial business growth. Holliday describes how DuPont developed a three-pronged strategy to translate the concept of sustainability into nuts-and-bolts business practices. Focusing on integrated science, knowledge intensity, and productivity improvement, the strategy was accompanied by a new way to measure progress quantitatively. Sustainable growth should be viewed not as a program for stepped-up environmental performance but as a comprehensive way of doing business, one that delivers tremendous economic value and opens up new opportunities. Ultimately, companies will find that they can generate substantial business value through sustainability while both enhancing the quality of life around the world and protecting the environment. PMID:11550629

  10. Du Pont Classifications of 6 Supernovae

    NASA Astrophysics Data System (ADS)

    Morrell, N.; Shappee, Benjamin J.

    2016-06-01

    We report optical spectroscopy (range 370-910 nm) of six supernovae from the Backyard Observatory Supernova Search (BOSS) and the All-Sky Automated Survey for Supernovae (ASAS-SN) using the du Pont 2.5-m telescope (+ WFCCD) at Las Campanas Observatory on June 17 2016 UT. We performed a cross-correlation with a library of supernova spectra using the "Supernova Identification" code (SNID; Blondin and Tonry 2007, Ap.J.

  11. CCD images of Mars with the 1 M reflector atop Pic-du-Midi

    NASA Astrophysics Data System (ADS)

    Lecacheux, J.; Drossart, P.; Buil, C.; Laques, P.; Thouvenot, E.; Guerin, P.

    1991-02-01

    CCD images of high spatial resolution, in red filters near 800 nm, have been taken from the 1 m reflector of Pic-du-Midi Observatory during the opposition of Mars, between August and October 1988. In several of the images a bright elongated feature is observed with a longitudinal extension of more than 100 deg. Comparison with Viking mosaics shows that small variations of albedo may be attributed to wind transportation of surface deposits by the strong winds of Mars. Small changes observed between the 2 months observation may be attributed to localized dust clouds on Mars.

  12. Électrooxydation du mésoérythritol sur platine, modifié ou non par des adatomes, en milieu acide

    NASA Astrophysics Data System (ADS)

    Cherqaoui, A.; Chbihi, M. El M.; Takky, D.; Kokoh, K. B.; Leger, J.-M.; Lamy, C.

    1999-03-01

    The electrocatalytic oxidation of meso-erythritol has been studied in 0.1 M HClO4 on platinum and on adatoms modified platinum. Preliminary investigations by cyclic voltammetry showed that erythritol was not reactive on a Pt electrode. Underpotential deposition of lead or thallium adatoms at platinum allowed to increase significantly the current densities. Long-time electrolyses were carried out using a three potential plateau program with different values of the oxidation potentials. Chromatographic analyses showed that the oxidation of erythritol led mainly to erythrose, erythrulose and to erythronic acid. Otherwise, electrolysis of erythritol on a Pt-Tl modified electrode orientated selectively the distribution of the reaction products towards the formation of erythrulose. L'oxydation électrocatalytique du mésoérythrytol a été étudiée en milieu acide HClO4 0,1 M sur le platine modifié ou non par des adatomes métalliques. Les études préliminaires réalisées par voltammétrie cyclique montrent que l'érythritol est très peu réactif sur le platine seul. La modification de la surface de l'électrode par dépôt en sous-tension d'adatomes de plomb et de thallium permet d'augmenter les densités de courant. Les électrolyses prolongées sont réalisées à l'aide d'un programme à trois paliers de potentiel et pour différentes valeurs de potentiel d'oxydation. Les analyses chromatographiques montrent que les produits d'oxydation sont l'érythrose, l'érythrulose et l'acide érythronique. D'autre part l'oxydation de l'érythritol sur le platine modifié par des adatomes de thallium conduit à une production sélective d'érythrulose.

  13. La reconstruction du sourcil par greffon composite du cuir chevelu: une astuce pour faciliter la technique

    PubMed Central

    El Omari, Mounia; El Mazouz, Samir; Gharib, Noureddine; EL Abbassi, Abdallah

    2015-01-01

    Les sourcils jouent un rôle important dans l’équilibre esthétique du visage. Leur reconstruction ou ophriopoïése, après séquelle de brûlure fait partie intégrante du programme de réhabilitation de la face brûlée. Plusieurs techniques ont été décrites. Nous insistons ici sur l'intérêt d'une technique simple, à la portée de tous les chirurgiens, et dont la méthode et les résultats peuvent être améliorés par un dessin bien planifié des zones donneuse et receveuse: la greffe composite prélevée au niveau du cuir chevelu dessinée à l'aide d'un calque du sourcil controlatéral. PMID:26401195

  14. Suivi après le traitement du cancer du sein

    PubMed Central

    Sisler, Jeffrey; Chaput, Geneviève; Sussman, Jonathan; Ozokwelu, Emmanuel

    2016-01-01

    Résumé Objectif Offrir aux médecins de famille un résumé des recommandations fondées sur les données probantes pour guider les soins aux survivantes traitées pour le cancer du sein. Qualité des données Une recherche documentaire a été effectuée dans MEDLINE entre 2000 et 2016 à l’aide des mots-clés anglais suivants : breast cancer, survivorship, follow-up care, aftercare, guidelines et survivorship care plans, en se concentrant sur la revue des lignes directrices publiées récemment par les organismes nationaux de cancérologie. Les données étaient de niveaux I à III. Message principal Les soins aux survivantes comportent 4 facettes : surveillance et dépistage, prise en charge des effets à long terme, promotion de la santé et coordination des soins. La surveillance des récidives ne se traduit que par une mammographie annuelle, et le dépistage d’autres cancers doit suivre les lignes directrices basées sur la population. La prise en charge des effets à long terme du cancer et de son traitement aborde des problèmes courants tels la douleur, la fatigue, le lymphœdème, la détresse et les effets indésirables des médicaments, de même que les préoccupations à long terme comme la santé du cœur et des os. La promotion de la santé met en relief les bienfaits de l’activité chez les survivantes du cancer, avec l’accent mis sur l’activité physique. Les soins aux survivantes sont de meilleure qualité lorsque divers services et professionnels de la santé participent aux soins, et le médecin de famille joue un rôle important dans la coordination des soins. Conclusion Les médecins de famille sont de plus en plus souvent les principaux fournisseurs de soins de suivi après le traitement du cancer du sein. Le cancer du sein doit être considéré comme une affection médicale chronique, même chez les femmes en rémission, et les patientes profitent de la même approche que celle utilisée pour les autres affections chroniques en

  15. ASNT certification of thermographers at DuPont Company

    NASA Astrophysics Data System (ADS)

    Eads, Lowry G.; Spring, Robert W.

    1996-03-01

    DuPont is one of the world's largest petrochemical firms. Infrared thermography has been a key nondestructive test method used in the predictive/preventive maintenance (PPM) areas for many years. This paper discusses the reasons why DuPont chooses to use the qualification and certification standards of the American Society for Nondestructive Testing (ASNT) to establish a certification program for thermographers.

  16. Oncoplastie avec conservation mammaire dans le traitement du cancer du sein: à propos de 16 cas

    PubMed Central

    Bouzoubaa, Wail; Laadioui, Meryam; Jayi, Sofia; Alaoui, Fatime Zahra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Moulay Abdelilah

    2015-01-01

    Le cancer du sein est actuellement le cancer le plus fréquent chez la femme, et pose un véritable problème diagnostique et thérapeutique. Le dépistage des lésions à un stade de plus en plus précoce, a permis une extension des indications du traitement conservateur radiochirurgical, qui était initialement limitées aux tumeurs de moins de 3 cm, unifocales, non inflammatoires. Par ailleurs, l'utilisation de traitements préopératoires permet d’étendre les indications du traitement conservateur à des tumeurs plus volumineuses. Parallèlement à cette extension des indications de conservation mammaire, on a observé le développement de nouvelles approches thérapeutiques notamment la chirurgie oncoplastique, technique du ganglion sentinelle et chirurgie stéréotaxique, dont les résultats initiaux sont très encouragent. A travers cette étude réalisée dans le service de gynécologie et obstétrique II du CHU HASSAN II de FES au MAROC, après l'analyse rétrospective de 16 patientes traitées par traitement conservateur et oncoplastie, nous avons voulus montrer notre aptitude a réalisé ses techniques chirurgicales et a bien prendre en charge ces patientes, mais aussi évaluer ces techniques en termes de résultat carcinologique et de résultat esthétique, aussi en terme de survie globale, survie sans métastase et en termes de récidive locale entre les plasties mammaires et les traitements usuels: mastectomie et traitement conservateur classique. PMID:26430477

  17. La fin du jeûne?

    PubMed Central

    Naugler, Christopher; Sidhu, Davinder

    2014-01-01

    Résumé Objectif Présenter une mise à jour sur l’utilité clinique de ne pas être à jeun par rapport à l’être pour l’analyse des lipides dans le but d’améliorer l’observance par les patients, leur sécurité et l’évaluation clinique dans les tests du cholestérol. Qualité des données Les recommandations sont classées comme étant fondées sur des données probantes fortes, acceptables ou faibles (conflictuelles ou insuffisantes), selon les classifications adoptées par le Groupe d’étude canadien sur les soins de santé préventifs. Message principal Le dépistage de la dyslipidémie comme facteur de risque de coronaropathie et la prescription de médicaments hypolipidémiants sont des activités importantes en soins primaires. De récentes données probantes remettent en question la nécessité d’être à jeun pour la mesure des lipides. Dans des études sur la population, le cholestérol total, le cholestérol à lipoprotéines de haute densité et le cholestérol à lipoprotéines autres qu’à haute densité variaient tous d’en moyenne 2 % à jeun. Pour un dépistage de routine, la mesure du cholestérol sans être à jeun est maintenant une option de rechange raisonnable à l’analyse à jeun. Pour les patients diabétiques, l’exigence d’être à jeun peut représenter un important problème de sécurité en raison des possibilités d’hypoglycémie. Pour la surveillance des triglycérides et du cholestérol à lipoprotéines de basse densité chez les patients qui prennent des médicaments hypolipidémiants, le jeûne devient important. Conclusion Être à jeun pour la détermination routinière des niveaux lipidiques est largement inutile et il est improbable que le jeûne influence la stratification du risque clinique chez le patient, tandis que la mesure sans être à jeun pourrait améliorer l’observance par le patient et sa sécurité.

  18. Mesure du taux de la capture radiative du muon par l'hydrogene liquide

    NASA Astrophysics Data System (ADS)

    Jonkmans, Guy

    À basse énergie, l'interaction faible entre leptons et quarks est décrite par une interaction de la forme courant × courant de type V - A. La présence de l'interaction forte induit des couplages additionnels qui doivent être déterminés expérimentalement. De ceux-ci, le couplage pseudoscalaire induit, gp , est mesuré avec la plus grande incertitude et fait l'objet de la présente recherche. L'hypothèse du Courant Axial Partiellement Conservé (CAPC) et l'usage de la relation de Goldberger-Treiman relie gp au couplage axial ga . Cette relation a été vérifiée traditionnellement par la Capture Ordinaire du Muon (COM) à une valeur fixe du moment de transfert q. La Capture Radiative du Muon (CRM), m- p-->nnmg , est un meilleur outil pour l'étude de gp à cause de sa dépendance variable en q2 qui offre une plus grande sensibilité dans la partie à haute énergie du spectre des photons. Toutefois, le petit rapport d'embranchement (~10-8) de la CRM par rapport à la désintégration du muon a retardé cette mesure jusqu'à ce jour. La théorie et les difficultés expérimentales associées à la détection des photons de CRM sont présentées au deuxième chapitre. On décrit ensuite, au troisième chapitre, les composantes du système de détection. Ce détecteur est un spectromètre à paires de grand angle solide (~3p) et qui permet l'observation des photons par l'analyse des électrons et des positrons de photo-conversion. Ainsi, le bruit de fond important des neutrons de la COM ne constitue pas un problème pour cette mesure. Nous décrivons, au quatrième chapitre, toutes les étapes de l'analyse, nécessaires pour la réduction des multiples bruits de fond. Le cinquième chapitre présente le calcul des efficacités ainsi que l'estimation des erreurs systématiques. Le sixième chapitre démontre comment l'on extrait le rapport d'embranchement pour la CRM ainsi que la valeur ae gp . On insiste sur la dépendance de gp en fonction de la valeur de

  19. The Pic du Midi solar survey

    NASA Astrophysics Data System (ADS)

    Koechlin, L.

    2015-12-01

    We carry a long term survey of the solar activity with our coronagraphic system at Pic du Midi de Bigorre in the French Pyrenees (CLIMSO). It is a set of two solar telescopes and two coronagraphs, taking one frame per minute for each of the four channels : Solar disk in H-α (656.28 nm), prominences in H-α, disk in Ca II (393.3 nm), prominences in He I (1083 nm), all year long, weather permitting. Since 2015 we also take images of the FeXIII corona (1074.7 nm) at the rate of one every 10 minutes. These images cover a large field: 1.25 solar diameter, 2k*2K pixels, and are freely downloadable form a database. The improvements made since 2015 concern an autoguiding system for better centering of the solar disk behind the coronagraphic masks, and a new Fe XIII channel at λ=1074.7 nm. In the near future we plan to provide radial velocity maps of the disc and polarimetry maps of the disk and corona. This survey took its present form in 2007 and we plan to maintain image acquisition in the same or better experimental conditions for a long period: one or several solar cycles if possible. During the partial solar eclipse of March 20, 2015, the CLIMSO instruments and the staff at Pic du Midi operating it have provided several millions internet users with real time images of the Sun and Moon during all the phenomenon.

  20. Le spasme du sanglot chez les nourrissons

    PubMed Central

    Goldman, Ran D.

    2015-01-01

    Résumé Question Des enfants qui fréquentent ma clinique ont des épisodes semblables à des convulsions pendant lesquels ils pleurent et retiennent leur souffle au point de faire survenir une cyanose et de perdre conscience. Les résultats à l’examen ou aux investigations sont normaux et les pédiatres consultés ne font pas d’autres investigations. Les spasmes du sanglot sont-ils communs et quels genres d’investigations faut-il faire? Réponse Le spasme du sanglot est un trouble non épileptique paroxysmal bénin qui se produit chez les enfants en santé de six à 48 mois. Les épisodes commencent par une provocation, comme un bouleversement émotionnel ou une blessure mineure, et peuvent progresser en une retenue de la respiration, une cyanose et une syncope. Les épisodes sont extrêmement effrayants à regarder mais ont des conséquences bénignes. Une fois le diagnostic clinique posé, on recommande de faire passer un électrocardiogramme et d’exclure la possibilité d’une anémie, mais aucune autre investigation ou demande de consultation n’est nécessaire.

  1. Élimination du bore du silicium par plasma inductif sous champ électrique

    NASA Astrophysics Data System (ADS)

    Combes, R.; Morvan, D.; Picard, G.; Amouroux, J.

    1993-05-01

    We analyzed purification mechanisms of silicon by inductive plasma with a fluoride slag. The aim is to study boron elimination from doped electronic grade silicon in function of the nature of the slag to obtain a photovoltaic grade silicon. The steady began with the calculation and the comparison of the stability diagram of boron compounds in presence of CaF2, BaF2 and MgF2. This study led us to conclude that BaF2 is the better slag for silicon purification. This has been confirmed by experience. In a second time, we made purifications under electric bias to enhance slag efficiency. We noticed that BaF2 is more sensitive to electric bias than other slags. Nous avons analysé le mécanisme de purification du silicium sous plasma inductif en présence d'un laitier fluoré. L'objectif principal est d'étudier l'élimination du bore du silicium électronique dopé en fonction de la nature du fluorure pour obtenir un silicium de qualité photovoltaïque. L'étude a commencé par l'établissement et la comparaison de diagrammes des composés du bore en présence de CaF2, de MgF2 et de BaF2. Nous avons déduit de cette première étude que BaF2 est le meilleur laitier pour la purification du silicium. Ceci a été corroboré par l'expérience. Nous avons ensuite opéré en présence d'un champ électrique dans le but d'améliorer encore l'efficacité des laitiers. Nous avons constaté que BaF2 est plus sensible au champ électrique que les deux autres laitiers utilisés.

  2. Brain stem hypoplasia associated with Cri-du-Chat syndrome.

    PubMed

    Hong, Jin Ho; Lee, Ha Young; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu

    2013-01-01

    Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries. PMID:24265573

  3. Brain Stem Hypoplasia Associated with Cri-du-Chat Syndrome

    PubMed Central

    Hong, Jin Ho; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu

    2013-01-01

    Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries. PMID:24265573

  4. Depleted uranium (DU): a holistic consideration of DU and related matters.

    PubMed

    Hamilton, E I

    2001-12-17

    Following the use of depleted uranium (DU) during the Gulf and Balkan conflicts, unnecessary and costly confusion has existed for some 11 years concerning the hazard it constitutes, despite the fact that sufficient data are available to answer most of the relevant questions. In tracing the significance of uranium in the environment and humans, too much reliance is still placed upon the extrapolation of animal data. The existing radiological nomenclature is far too involved and complex to understand, let alone implement. The excellence of early health physics seems to have been lost, and hence there is a failure to utilise the large body of knowledge, and the manner in which it was obtained, in other disciplines. Health physics has failed to understand the nature of some natural processes that ultimately control radiation dose to the environment and humans. Examination of three types of DU, in particular the highly radioactive and potentially hazardous unprocessed, spent-reactor uranium fuel debris (UDU), alluded to as hot particles, has been poorly studied on the basis of scarcity in the environment. Fundamental geological processes are described which illustrate that, as a consequence of routine operation of nuclear reprocessing plants, especially in the past, and following reactor accidents, natural processes can result in an enrichment of DU particles in most types of sediment. Failure to grasp essential geological processes in relation to the dispersion of radionuclides in the environment is detrimental to public acceptance of an essential form of energy in association with others.

  5. Radiation Transport

    SciTech Connect

    Urbatsch, Todd James

    2015-06-15

    We present an overview of radiation transport, covering terminology, blackbody raditation, opacities, Boltzmann transport theory, approximations to the transport equation. Next we introduce several transport methods. We present a section on Caseology, observing transport boundary layers. We briefly broach topics of software development, including verification and validation, and we close with a section on high energy-density experiments that highlight and support radiation transport.

  6. Carte du Ciel, San Fernando zone

    NASA Astrophysics Data System (ADS)

    Abad, C.

    2014-06-01

    An updated summary of a future large astrometric catalogue is presented, based on the two most important astrometric projects carried out by the Real Instituto y Observatorio de la Armada de San Fernando (ROA). The goal is to make a catalogue of positions and proper motions based on ROA's Cart du Ciel (CdC) and the Astrographic Catalogue (AC) San Fernando zone plates, and the HAMC2 meridian circle catalogue. The CdC and AC plates are being reduced together to provide first-epoch positions while HAMC2 will provide second-epoch ones. New techniques have been applied, that range from using a commercial flatbed scanner to the proper reduction schemes to avoid systematics from it. Only thirty plates (out of 540) remain to be processed, due to scanning problems that are being solved.

  7. Le mouvement du pôle

    NASA Astrophysics Data System (ADS)

    Bizouard, Christian

    2012-03-01

    Les variations de la rotation terrestre. En conditionnant à la fois notre vie quotidienne, notre perception du ciel, et bon nombre de phénomènes géophysiques comme la formation des cyclones, la rotation de la Terre se trouve au croisement de plusieurs disciplines. Si le phenomena se faisait uniformément, le sujet serait vite discuté, mais c'est parce que la rotation terrestre varie, même imperceptiblement pour nos sens, dans sa vitesse angulaire comme dans la direction de son axe, qu'elle suscite un grand intérêt. D'abord pour des raisons pratiques : non seulement les aléas de la rotation terrestre modi_ent à la longue les pointés astrométriques à un instant donné de la journée mais in_uencent aussi les mesures opérées par les techniques spatiales ; en consequence l'exploitation de ces mesures, par exemple pour déterminer les orbites des satellites impliqués ou pratiquer le positionnement au sol, nécessite une connaissance précise de ces variations. Plus fondamentalement, elles traduisent les propriétés globales de la Terre comme les processus physiques qui s'y déroulent, si bien qu'en analysant les causes des fluctuations observées, on dispose d'un moyen de mieux connaître notre globe. La découverte progressive des fluctuations de la rotation de la Terre a une longue histoire. Sous l'angle des techniques d'observation, trois époques se pro-celle du pointé astrométrique à l'oeil nu, à l'aide d'instruments en bois ou métalliques (quart de cercle muraux par exemple). À partir du XVIIe siècle débute l'astrométrie télescopique dont les pointés sont complétés par des datations de plus en plus précises grâce à l'invention d'horloges régulées par balancier. Cette deuxième époque se termine vers 1960, avec l'avènement des techniques spatiales : les pointés astrométriques sont délaissés au profit de la mesure ultra-précise de durées ou de fréquences de signaux électromagnétiques, grâce à l'invention des horloges

  8. Impact socio professionnel de la libération chirurgicale du syndrome du canal carpien

    PubMed Central

    Kraiem, Aouatef Mahfoudh; Hnia, Hajer; Bouzgarrou, Lamia; Henchi, Mohamed Adnène; Khalfallah, Taoufik

    2016-01-01

    L’objectif de notre travail était d’étudier les conséquences socioprofessionnelles d’une libération chirurgicale du SCC. Il s’agit d’une étude transversale portant sur les sujets opérés pour un SCC d’origine professionnelle ; recensés dans le Service de Médecine de Travail et de Pathologies Professionnelles au CHU Tahar Sfar de Mahdia en Tunisie sur une période de 8 ans allant du 1 Janvier 2006 au mois Décembre 2013. Le recueil des données s’est basé sur une fiche d’enquête, portant sur la description des caractéristiques socioprofessionnelles, médicales, et sur le devenir professionnel des participants. Pour étudier les contraintes psychosociales au travail, nous avons adopté le questionnaire de Karasek. La durée d’arrêt de travail après libération chirurgicale du SCC était significativement liée à l’existence d’autres troubles musculo-squelettiques autre que le SCC, la déclaration du SCC en maladie professionnelle et à l’ancienneté professionnelle des salariés. Quant au devenir professionnel des salariés opérés, 50,7% ont gardé le même poste, 15,3% ont bénéficié d’un aménagement de poste et 33,8% ont bénéficié d’un changement de poste dans la même entreprise. Le devenir professionnel de ces salariés était corrélé à leurs qualifications professionnelles et au type de l’atteinte sensitive et/ou motrice du nerf médian à l’EMG. Un certain nombre de facteurs non lésionnels déterminaient la durée de l’arrêt de travail, alors que le devenir professionnel des opérés pour SCC dépendait essentiellement de leurs qualifications professionnelles et des données de l’électromyogramme. Il est certain que des travaux beaucoup plus larges permettraient d’affiner encore ces résultats. PMID:27800089

  9. Classification moléculaire du cancer du sein au Maroc

    PubMed Central

    Fouad, Abbass; Yousra, Akasbi; Kaoutar, Znati; Omar, El Mesbahi; Afaf, Amarti; Sanae, Bennis

    2012-01-01

    Introduction La classification moléculaire des cancers du sein basée sur l'expression génique puis sur le profil protéique a permis de distinguer cinq groupes moléculaires: luminal A, luminal B, Her2/neu, basal-like et non-classées. L'objectif de cette étude réalisée au CHU Hassan II de Fès est de classer 335 cancers du sein infiltrant en groupes moléculaires, puis de les corréler avec les caractéristiques clinicopathologiques. Méthodes Etude rétrospective étalée sur 45 mois, comportant 335 patientes colligées au CHU pour le diagnostic et le suivi. Les tumeurs sont analysées histologiquement et classées après une étude immunohistochimique en groupes: luminal A, luminal B, Her2+, basal-like et non-classées. Résultats 54.3% des tumeurs sont du groupe luminal A, 16% luminal B, 11.3% Her2+, 11.3% basal-like et 7% non-classées. Le groupe luminal A renferme le plus faible taux de grade III, d'emboles vasculaires ainsi que de métastases; alors que le groupe des non-classées et basal-like représentent un taux élevé de grade III, une faible proportion d'emboles vasculaires et d'envahissement ganglionnaire. Ces facteurs sont significativement élevés dans les groupes luminal B et Her2+ avec un taux de survie globale de 78% et 76% respectivement. Dans le groupe luminal A, la survie globale des patientes est élevée (87%) alors qu'elle n'est que de 49% dans le groupe des triples négatifs (basal-like et non-classés). Conclusion Le groupe luminal B est différent du luminal A et il est de pronostic péjoratif vis à vis du groupe Her2+. Les caractéristiques clinicopathologiques concordent avec le profil moléculaire donc devraient être pris en considération comme facteurs pronostiques. PMID:23396646

  10. Chamber transport

    SciTech Connect

    OLSON,CRAIG L.

    2000-05-17

    Heavy ion beam transport through the containment chamber plays a crucial role in all heavy ion fusion (HIF) scenarios. Here, several parameters are used to characterize the operating space for HIF beams; transport modes are assessed in relation to evolving target/accelerator requirements; results of recent relevant experiments and simulations of HIF transport are summarized; and relevant instabilities are reviewed. All transport options still exist, including (1) vacuum ballistic transport, (2) neutralized ballistic transport, and (3) channel-like transport. Presently, the European HIF program favors vacuum ballistic transport, while the US HIF program favors neutralized ballistic transport with channel-like transport as an alternate approach. Further transport research is needed to clearly guide selection of the most attractive, integrated HIF system.

  11. 76 FR 68124 - Television Broadcasting Services; Fond du Lac, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Fond du Lac, WI AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: In this document, the Commission denies a petition...

  12. 1. Historic American Buildings Survey, drawn by Pierre du Simitiere ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey, drawn by Pierre du Simitiere (papers in Philadelphia Library) DRAWING OF REDWOOD LIBRARY IN 1768. - Redwood Library, 50 Bellevue Avenue, Newport, Newport County, RI

  13. The Cri-Du-Chat Syndrome: A Case Study.

    ERIC Educational Resources Information Center

    Sykes, Stewart C.; Christie, Margarette A.

    1987-01-01

    The developmental history of a 14-year-old girl with Cri-Du-Chat Syndrome (a genetic disorder characterized by a distinctive cry and severe physical and intellectual disabilities) is reported. (Author/DB)

  14. Lymphome primitif du sein: à propos d'un cas

    PubMed Central

    Njoumi, Noureddine; Najih, Mohamed; Haqqi, Laila; Atolou, Gilles; Bougtab, Abdessalm; Hachi, Hafid; Benjelloun, Samir

    2012-01-01

    Le lymphome primitif du sein est une entité histologique très rare du cancer du sein. Les aspects cliniques et radiologiques ne présentent pas de spécificités particulières. Le diagnostic est souvent retardé. Le traitement se base essentiellement sur la chimiothérapie. Le pronostic est globalement péjoratif. Nous rapportons un cas de lymphome malin non Hodgkinien primitif du sein chez une patiente de 38 ans. Parallèlement une revue de la littérature est entreprise évoquant les aspects épidémiologiques, cliniques, histologiques et thérapeutiques de ce néoplasme. PMID:22937198

  15. Peters anomaly in cri-du-chat syndrome.

    PubMed

    Hope, William C; Cordovez, Jose A; Capasso, Jenina E; Hammersmith, Kristin M; Eagle, Ralph C; Lall-Trail, Joel; Levin, Alex V

    2015-06-01

    The cri-du-chat syndrome is a rare genetic disorder caused by deletions in the short arm of chromosome 5. It presents with a distinctive catlike high-pitched cry, psychomotor delays, microcephaly, craniofacial abnormalities, and, in many cases, ocular findings. We report the first child with cri-du-chat and the findings of unilateral corneal staphyloma due to Peters anomaly and retinal dysplasia. PMID:26059676

  16. Determination of periodontopathogens in patients with Cri du chat syndrome

    PubMed Central

    Ballesta-Mudarra, Sofía; Torres-Lagares, Daniel; Rodríguez-Caballero, Ángela; Yáñez-Vico, Rosa M.; Solano-Reina, Enrique; Perea-Pérez, Evelio

    2013-01-01

    Objectives: Cri du chat syndrome is a genetic alteration associated with some oral pathologies. However, it has not been described previously any clinical relationship between the periodontal disease and the syndrome. The purpose of this comparative study was to compare periodontopathogenic flora in a group with Cri du chat syndrome and another without the síndrome, to assess a potential microbiological predisposition to suffer a periodontitis. Study Design: The study compared nineteen subjects with Cri du chat Syndrome with a control group of nineteen patients without it. All patients were clinically evaluated by periodontal probing, valuing the pocket depth, the clinical attachmente level and bleeding on probing. There were no significant differences between both groups. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia and Treponema denticola were detected by multiplex-PCR using 16S rDNA (microIDENT). Results: When A. actinomycetemcomitans, P. gingivalis, P. intermedia and T. denticola were compared, no statistically significant differences were found between the two groups (p>0.05). The value of T. forsythia was significantly higher for Cri du chat syndrome (31.6%) than for the control group (5.3%). The odds ratio for T. forsythia was 8.3. Conclusions: In the present study T. forsythia is associated with Cri du chat syndrome subjects and not with healthy subjects. Key words:Cri du Chat syndrome, periodontal health, microbiology, special care dentistry. PMID:24121919

  17. Transport proteins.

    PubMed

    Thatcher, Jack D

    2013-04-16

    This Teaching Resource provides and describes two animated lessons that illustrate general properties of transport proteins. The lesson called "transport protein classes" depicts major classes and subclasses of transport proteins. The "transporters, mechanism of action" lesson explains how transporters and P class ATPase (adenosine triphosphatase) pumps function. These animations serve as valuable resources for any collegiate-level course that describes these important factors. Courses that might use them include introductory biology, biochemistry, cell biology, physiology, and biophysics.

  18. Mise à jour sur le nouveau vaccin 9-valent pour la prévention du virus du papillome humain

    PubMed Central

    Yang, David Yi; Bracken, Keyna

    2016-01-01

    Résumé Objectif Informer les médecins de famille quant à l’efficacité, à l’innocuité, aux effets sur la santé publique et à la rentabilité du vaccin 9-valent contre le virus du papillome humain (VPH). Qualité des données Des articles pertinents publiés dans PubMed jusqu’en mai 2015 ont été examinés et analysés. La plupart des données citées sont de niveau I (essais randomisés et contrôlés et méta-analyses) ou de niveau II (études transversales, cas-témoins et épidémiologiques). Des rapports et recommandations du gouvernement sont aussi cités en référence. Message principal Le vaccin 9-valent contre le VPH, qui offre une protection contre les types 6, 11, 16, 18, 31, 33, 45, 52 et 58 du VPH, est sûr et efficace et réduira encore plus l’incidence des infections à VPH, de même que les cas de cancer lié au VPH. Il peut également protéger indirectement les personnes non immunisées par l’entremise du phénomène d’immunité collective. Un programme d’immunisation efficace peut prévenir la plupart des cancers du col de l’utérus. Les analyses montrent que la rentabilité du vaccin 9-valent chez les femmes est comparable à celle du vaccin quadrivalent original contre le VPH (qui protège contre les types 6, 11, 16 et 18 du VPH) en usage à l’heure actuelle. Toutefois, il faut investiguer plus en profondeur l’utilité d’immuniser les garçons avec le vaccin 9-valent contre le VPH. Conclusion en plus d’être sûr, le vaccin 9-valent protège mieux contre le VPH que le vaccin quadrivalent. Une analyse coûtefficacité en favorise l’emploi, du moins chez les adolescentes. Ainsi, les médecins devraient recommander le vaccin 9-valent à leurs patients plutôt que le vaccin quadrivalent contre le VPH.

  19. School Transportation.

    ERIC Educational Resources Information Center

    Executive Educator, 1990

    1990-01-01

    This special section on student transportation offers a case study of a school system that recycles buses for safety drills; articles on fuel-saving strategies, the pros and cons of contracting for transportation services or operating a publicly owned bus fleet, and advice on full cost accounting for transportation costs; and a transportation…

  20. Transport Experiments

    NASA Technical Reports Server (NTRS)

    Hall, Timothy M.; Wuebbles, Donald J.; Boering, Kristie A.; Eckman, Richard S.; Lerner, Jean; Plumb, R. Alan; Rind, David H.; Rinsland, Curtis P.; Waugh, Darryn W.; Wei, Chu-Feng

    1999-01-01

    MM II defined a series of experiments to better understand and characterize model transport and to assess the realism of this transport by comparison to observations. Measurements from aircraft, balloon, and satellite, not yet available at the time of MM I [Prather and Remsberg, 1993], provide new and stringent constraints on model transport, and address the limits of our transport modeling abilities. Simulations of the idealized tracers the age spectrum, and propagating boundary conditions, and conserved HSCT-like emissions probe the relative roles of different model transport mechanisms, while simulations of SF6 and C02 make the connection to observations. Some of the tracers are related, and transport diagnostics such as the mean age can be derived from more than one of the experiments for comparison to observations. The goals of the transport experiments are: (1) To isolate the effects of transport in models from other processes; (2) To assess model transport for realistic tracers (such as SF6 and C02) for comparison to observations; (3) To use certain idealized tracers to isolate model mechanisms and relationships to atmospheric chemical perturbations; (4) To identify strengths and weaknesses of the treatment of transport processes in the models; (5) To relate evaluated shortcomings to aspects of model formulation. The following section are included:Executive Summary, Introduction, Age Spectrum, Observation, Tropical Transport in Models, Global Mean Age in Models, Source-Transport Covariance, HSCT "ANOY" Tracer Distributions, and Summary and Conclusions.

  1. Une étude rétrospective sur l'incidence de l'insuffisance rénale chronique dans le service de Médecine Interne et Néphrologie du Centre Hospitalier Universitaire d'Antananarivo

    PubMed Central

    Ramilitiana, Benja; Ranivoharisoa, Eliane Mikkelsen; Dodo, Mihary; Razafimandimby, Evanirina; Randriamarotia, Willy Franck

    2016-01-01

    L'insuffisance rénale chronique est un problème de santé publique au niveau mondial. Dans les pays développés, cette affection survient essentiellement chez les sujets âgés, mais en Afrique, elle s'installe plutôt chez les sujets jeunes actifs. C'est une affection de lourde prise en charge dans un pays à faible revenu à cause de ses coûts. Notre but est de décrire les aspects épidémiologiques des nouveaux cas d'insuffisance rénale chronique à Madagascar. Il s'agit d'une étude rétrospective descriptive de 3 ans partant du 1er janvier 2007 au 31 décembre 2009 dans le service de Médecine Interne et Néphrologie du Centre Hospitalier Universitaire d'Antananarivo portant sur 239 patients diagnostiqués comme une insuffisance rénale chronique. L'incidence était de 8,51% parmi les patients hospitalisés dans le service. L’âge moyen des patients était de 45,4 ans avec des extrêmes de 16 et 82 ans et un sex-ratio de 1,46. Le principal antécédent était l'hypertension artérielle (59,8%). L'insuffisance rénale chronique était terminale dans 75,31% des cas (n=180). Les causes de l'insuffisance rénale chronique étaient dominées par la glomérulonéphrite chronique (40,1%), la néphroangiosclérose (35,5%). L'hémodialyse était réalisée chez 3 patients (1,26%), aucun patient n’était pas programmé pour une greffe rénale. Le taux de mortalité dans le service était de 28,87%. L'insuffisance rénale chronique est une maladie de pronostic redoutable et handicapante qui affecte les sujets jeunes à Madagascar. Son traitement reste inaccessible dans la majorité des patients. L'accent doit donc être mis principalement sur la prévention notamment une bonne prise en charge précoce des infections, de l'hypertension artérielle et du diabète pour réduire ses impacts négatifs sur la santé communautaire et publique. Le projet de la transplantation rénale - donneur vivant, traitement efficace et moins coûteux par rapport à l

  2. Modelisation du Signal Radar EN Milieu Stratifie et Evaluation de Techniques de Mesure de L'humidite du Sol

    NASA Astrophysics Data System (ADS)

    Boisvert, Johanne

    La presente etude se penche sur des problemes relies a l'echantillonnage de l'humidite de sol et a l'estimation du signal radar sur sols nus. Le travail se divise en deux volets. Le volet 1 evalue trois techniques de mesure de l'humidite du sol (gravimetrie, reflectometrie temporelle et sonde dielectrique) et deux protocoles d'echantillonnage. Dans le volet 2, un modele de simulation du signal en milieu stratifie est developpe, et les estimes de signal obtenus sont compares aux estimes bases uniquement sur une valeur moyenne d'humidite du sol prise sur une profondeur fixe d'echantillonnage. Les differences entre les deux estimes dependent de la frequence et du choix judicieux de la profondeur d'echantillonnage; elles sont plus importantes aux faibles angles et en polarisation HV, puis VV. Le modele de simulation a aussi ete utilise pour etudier la profondeur de penetration du signal et en deduire la profondeur optimale d'echantillonnage en tenant compte des caracteristiques du signal. Une variation de 25 ^circ de l'angle d'incidence a peu d'effet sur la profondeur de penetration en bande Ku; l'ecart reste inferieur ou egal a 0,5 cm en bande C mais peut atteindre 1,3 cm en bande L. L'impact de la polarisation est nul en bande Ku mais croi t avec l'angle d'incidence en bande C et L. A 50^circ, il est, en moyenne de 1 cm en bande C et de 2 cm en bande L. En polarisation VV, la profondeur croi t avec une augmentation de l'angle alors que l'effet est inverse en polarisation HH. Deux methodes pour estimer la profondeur d'echantillonnage en conditions operationnelles sont presentees. Lorsqu'on inverse un modele pour estimer l'humidite du sol a partir du signal, ces methodes permettent aussi d'estimer l'epaisseur de sol representee par l'humidite ainsi estimee.

  3. La chirurgie du diaphragme sous aortique

    PubMed Central

    Moutakiallah, Younes; Maaroufi, Ilham; Aithoussa, Mahdi; Bamous, Mehdi; Abdou, Abdessamad; Atmani, Noureddine; Hatim, Abdedaïm; Amahzoune, Brahim; Bekkali, Youssef El; Boulahya, Abdelatif

    2016-01-01

    Le diaphragme sous aortique se caractérise par une certaine latence clinique et une faible morbi-mortalité. La chirurgie reste le traitement de choix malgré un réel risque de récurrence à long terme. Nous rapportons 18 patients opérés entre Avril 1994 et Mars 2011 pour diaphragme sous aortique d’âge moyen de 18,1±9,7 ans avec 11 patients de sexe masculin. Le diaphragme était de nature fibreuse chez 13 patients et fibro-musculaire chez 5 patients. Tous les patients ont été opérés par résection de diaphragme associée à une myectomie, une plastie aortique, une fermeture de communication interventriculaire et une ligature de canal artériel perméable respectivement chez 3, 3, 2 et 2 patients. La Mortalité opératoire était nulle et sans aucun cas de trouble de conduction postopératoire. Le suivi a duré en moyenne 44,3±36,8 mois sans aucun décès tardif. Deux patients ont présenté une récidive de diaphragme qui a nécessité une réopération avec bonne évolution. La tendance actuelle dans la chirurgie du diaphragme se fait vers des interventions précoces et des résections plus extensives. Cependant, le risque de récidive impose une surveillance échographique systématique et rapprochée. PMID:27516830

  4. Les rivières et les sources de la Plaine du Cul-de-Sac: extrait du rapport sur les eaux souterraines de la Plaine du Cul-de-Sac

    USGS Publications Warehouse

    Taylor, George C.; Lemoine, Rémy C.

    1949-01-01

    Les principales rivières de la Plaine du Cul-de-Sac, la Rivière Grise ou Grande Rivière du Cul-de-Sac et la Rivière Blanche, prennent naissance sur le flanc Nord du Massif de la Selle à des altitudes de 1,300 à 1,800 mètres au dessus du niveau de la mer. Elles coulent à l’amont à travers des gorges profondes et sont éloignées de 9 Kms. dans la partie central de la bordure Sud de la plaine.

  5. Du pont ''Freon'' helps tap geothermal wells for power

    SciTech Connect

    Not Available

    1984-07-01

    Low-grade heat from geothermal wells can now be harnessed to produce electricity by using Du Pont ''Freon'' IF as the power conversion fluid. The new system was developed by Turbonetics Energy Inc. The company's Organic Rankine Cycle (ORC) system takes advantage of the low boiling point (117F) of Du Pont ''Freon'' TF. Geothermal energy is harnessed by utilizing the heat from 200F to 400F water to vaporize the ''Freon'' power fluid. Then the fluid expands through a turbine and drives a generator. The system can produce from 600 kW of electric power.

  6. Baisse du HDL-cholestérol indicateur du stress oxydatif dans le diabète de type 2

    PubMed Central

    Kabamba, Arsène Tshikongo; Bakari, Salvius Amuri; Longanga, Albert Otshudi; Lukumwena, Zet Kalala

    2014-01-01

    L'hypercholestérolémie est étroitement liée au stress oxydatif. Lorsqu'il y a trop de cholestérol qui circule dans le sang, il n'est pas utilisé en totalité par les cellules et il risque de s'accumuler dans les vaisseaux sanguins. Cela peut entrainer la formation des plaques d'athérosclérose qui gênent la circulation sanguine et provoquent des accidents cardiovasculaires. Le stress oxydatif apparait très tôt dans l'histoire des complications du diabète de type 2, et est lié à l'oxydation du glucose mais aussi à la peroxydation lipidique. Le cholestérol-HDL est un marqueur important du stress oxydatif par sa capacité à faciliter la métabolisation du cholestérol, sa baisse est souvent considérée comme la source de beaucoup d'inquiétudes. L'objectif est l’évaluation de la variation du taux de cholestérol-HDL, marqueur du stress oxydatif, chez les patients diabétiques de type 2 dans la population congolaise. Nous avons inclus dans cette étude prospective des cas témoins des patients diabétiques de type 2 reconnus et diagnostiqués, et des témoins non diabétiques appariés selon l’âge et le sexe. Parallèlement au bilan biologique classique, une analyse d'un des facteurs de risque du stress oxydatif a été réalisée: baisse de HDL-Cholestérol. L’âge moyen des 30 patients diabétiques (47,77±10,78 ans) était comparable à celui des 30 témoins (48,83±10,73 ans). Une baisse significative du cholestérol-HDL dans le sang était observée chez 100% des diabétiques et 50% des témoins (p=0,0000). L'augmentation du HDL cholestérol permet d’éliminer le mauvais cholestérol en excès en nettoyant les tissus et en ramenant le cholestérol vers le foie. Lors du diabète de type 2 on constate une baisse sanguine sensible du taux de HDL-cholestérol, qui est signe indicateur du stress oxydatif. PMID:25767660

  7. Influence du chrome et du niobium sur l'équilibre α-γ dans les aluminiures de titane

    NASA Astrophysics Data System (ADS)

    Daloz, D.; Hazotte, A.; Lacaze, J.; Charpentier, M.

    2004-12-01

    L’influence du chrome et du niobium sur les transformations et équilibres de phases des aluminiures de titane dans le domaine biphasé a/g est étudiée par analyse thermique différentielle, dilatomètrie, et métallographie quantitative après traitements thermiques suivis de trempe. Les compositions et les taux de phases à l’équilibre sont déterminés pour différentes températures du domaine biphasé a/g. Les résultats sont comparés aux calculs thermodynamiques réalisés à l’aide d’une banque de données relative aux intermétalliques de base Ti-Al.

  8. Le traitement conservateur du cancer du sein: expérience d'une équipe tunisienne

    PubMed Central

    Dimassi, Kaouther; Gharsa, Anissa; Chanoufi, Mohammed Badis; Sfar, Ezzeddine; Chelli, Dalenda

    2014-01-01

    En Tunisie, le cancer du sein touche des femmes jeunes avec une taille moyenne au moment du diagnostic à 5 cm. Ces particularités font que la chirurgie radicale reste prédominante. Nous présentons dans ce travail l'expérience de notre équipe en matière de chirurgie conservatrice du cancer du sein. Le but de ce travail est d’évaluer les résultats de ce traitement. Etude rétrospective longitudinale, sur une période de 75 mois. Nous avons inclus toutes les patientes ayant bénéficié d'un traitement conservateur pour une tumeur maligne du sein. Ont été analysés: les caractéristiques épidémiologiques, les aspects radiologiques et histologiques. Le suivi des malades s'est basé sur la détection des récidives. Nous avons évalué le résultat esthétique à la fin de la radiothérapie. Le traitement conservateur a été réalisé dans 23.8% des cas. Le taux de récidives locales était de 6.8% avec une corrélation significative pour une taille tumorale > 30 mm (p= 0.009), l'association d'une composante intracanalaire (p= 0.035), le statut triple négatif (p= 0.003) et des marges d'exérèse < 5mm sans recoupes per-opératoires (p = 0.045). Les facteurs suivants étaient significativement liés au risque de survenue de métastases à distance: le statut triple négatif (p= 0.003), taille tumorale > 30mm (p = 0.006) et l'atteinte ganglionnaire (p = 0.001). Le résultat esthétique était satisfaisant dans 90% des cas. L'augmentation du nombre de patientes pouvant bénéficier d'une chirurgie conservatrice, doit passer impérativement par le développement et la promotion du diagnostic précoce et du dépistage par la mammographie. PMID:25810795

  9. Consequences experimentales des effets des fluctuations du vide sur la fluorescence parametrique et la generation du second harmonique en milieu confine

    NASA Astrophysics Data System (ADS)

    Robichaud, Luc

    Les fluctuations du vide, qui consistent en l'apparition momentanee de particules, ce qui est permit par le principe d'incertitude de Heisenberg, joue un role primordial dans les processus photoniques, en particulier les processus non-lineaires. Par la manipulation de ces fluctuations du vide a l'aide de confinement optique, on retrouve deux phenomenes particuliers : l'intensification de la fluorescence parametrique (Walker, 2008) et l'inhibition de la generation du second harmonique (Collette, 2013). Dans ce travail, on presente les resultats dans le cas classique ; c'est-a-dire sans fluctuations du vide et confinement. Par la suite, on presente les effets des fluctuations du vide et du confinement, ce qui mene aux deux effets mentionnes. Dans le cas de la fluorescence parametrique, le bruit quantique sur le champ interne et externe est calcule, le role du desaccord de phase dans le modele est expose et une generalisation tridimensionnelle est etudiee afin de generaliser la conception du modele d'un cas unidimensionnel a un cas tridimensionnel planaire. Dans le cas de la generation du second harmonique, les difficultes d'un modele purement tridimensionnel sont exposees et ensuite le cas limite planaire est etudie.

  10. Past Tense Morphology in Cri Du Chat Syndrome: Experimental Evidence

    ERIC Educational Resources Information Center

    Wium, Kristin; Kristoffersen, Kristian Emil

    2008-01-01

    It has been observed that persons with Cri du chat syndrome (CDCS) have poor language production. However, very few studies have addressed the question whether all aspects of language production are equally afflicted, or whether there are differences between for instance phonological and morphological abilities. The present study was aimed at…

  11. Consonants in Cri du Chat Syndrome: A Case Study

    ERIC Educational Resources Information Center

    Kristoffersen, Kristian Emil

    2008-01-01

    This article reports on a longitudinal case study of consonant productions in one Norwegian girl with Cri du chat syndrome from age 4;6 to age 9;4. It was shown that she had many articulation errors throughout the period of observation. Furthermore, these errors were shown to fall into three main categories: (1) errors of differentiation and…

  12. College of DuPage Administrative Internship Program.

    ERIC Educational Resources Information Center

    College of DuPage, Glen Ellyn, IL.

    This paper describes the objectives, policies, and procedures of the College of DuPage's Administrative Internship Program, whereby faculty members can gain broad administrative experience in key administrative areas of the college. The program seeks not only to broaden the experience of the individual intern, but to promote empathy among faculty…

  13. W. E. B. Du Bois: Reform, Will, and the Veil

    ERIC Educational Resources Information Center

    England, Lynn; Warner, W. Keith

    2013-01-01

    While W. E. B. Du Bois is widely recognized for his contributions to the sociology of race, his contributions to the foundations of sociology are largely ignored. His sociology is based on African American reformism, a version of pragmatism, and a contingent historicism. The basic view of sociology is one that emphasizes the role of chance and…

  14. College of DuPage Student Portrait, Fall Quarter 1999.

    ERIC Educational Resources Information Center

    College of DuPage, Glen Ellyn, IL. Office of Research and Planning.

    The report profiles the College of DuPage's (COD) fall quarter 1999 student body. It presents a brief history of the college's enrollment and a comparison of enrollments with other Illinois community colleges. It also provides demographic information on current students. Additionally, enrollment information is included by program, division, and…

  15. "The Moon Ring": A Conversation with Randy DuBurke.

    ERIC Educational Resources Information Center

    Pearson, Susan

    2003-01-01

    Discusses how the author, currently Editor-at-Large of Chronicle Books, chooses books to publish and discusses four attributes in a book that catch her eye. Presents an interview with Randy DuBurke and a conversation about his first picture book, "The Moon Ring." (SG)

  16. The first Pic du Midi photographs of Mars, 1909

    NASA Astrophysics Data System (ADS)

    Dollfus, A.

    2010-08-01

    This short paper comprises an English translation of the article '1909; Premieres photographies de Mars au Pic du Midi', by Audouin Dollfus, published in l'Astronomie, 2009 November, pp. 27-30, and printed here with the assistance of the Director of the BAA Mars Section, Dr Richard McKim.

  17. College of DuPage Institutional Portrait, 1999-2000.

    ERIC Educational Resources Information Center

    College of DuPage, Glen Ellyn, IL. Office of Research and Planning.

    This report profiles the College of DuPage (Illinois) and provides a quick reference regarding the institution. It contains information on facilities and land, finance, staff, college/student services, the Library, athletics, academic calendars, maps, and instructional programs. This report reflects the college structure as of September 1999 and…

  18. Transport Phenomena.

    ERIC Educational Resources Information Center

    McCready, Mark J.; Leighton, David T.

    1987-01-01

    Discusses the problems created in graduate chemical engineering programs when students enter with a wide diversity of understandings of transport phenomena. Describes a two-semester graduate transport course sequence at the University of Notre Dame which focuses on fluid mechanics and heat and mass transfer. (TW)

  19. Cost-Effective Remediation of Depleted Uranium (DU) at Environmental Restoration Sites

    SciTech Connect

    MILLER,MARK; GALLOWAY,ROBERT B.; VANDERPOEL,GLENN; JOHNSON,ED; COPLAND,JOHN; SALAZAR,MICHAEL

    1999-11-03

    Numerous sites in the United States and around the world are contaminated with depleted uranium (DU) in various forms. A prevalent form is fragmented DU originating from various scientific tests involving high explosives and DU during weapon-development programs, at firing practice ranges, or in war theaters where DU was used in armor-piercing projectiles. The contamination at these sites is typically very heterogeneous, with discrete, visually identifiable DU fragments mixed with native soil. The bulk-averaged DU activity is quite low, whereas DU fragments, which are distinct from the soil matrix, have much higher specific activity. DU is best known as a dark metal that is nearly twice as dense as lead, but DU in the environment readily weathers (oxidizes) to a distinctive bright yellow color that is quite visible. While the specific activity (amount of radioactivity per mass of soil) of DU is relatively low and presents only a minor radiological hazard, the fact that DU is radioactive and visually identifiable makes it desirable to remove the DU ''contamination'' from the environment. The typical approach to conducting this DU remediation is to use radiation-detection instruments to identify the contaminant and then to separate it from the adjacent soil, packaging it for disposal as radioactive waste. This process can be performed manually or by specialized, automated equipment. Alternatively, a more cost-effective approach might be simple mechanical or gravimetric separation of the DU fragments from the host soil matrix. At SNL/NM, both the automated and simple mechanical approaches have recently been employed. This paper discusses the pros/cons of the two approaches.

  20. Gated proton transport in aligned mesoporous silica films

    NASA Astrophysics Data System (ADS)

    Fan, Rong; Huh, Seong; Yan, Ruoxue; Arnold, John; Yang, Peidong

    2008-04-01

    Modulated proton transport plays significant roles in biological processes such as ATP synthesis as well as in technologically important applications including, for example, hydrogen fuel cells. The state-of-the-art proton-exchange membrane is the sulphonated tetrafluoroethylene copolymer Nafion developed by DuPont in the late 1960s, with a high proton conductivity. However, actively switchable proton conduction, a functional mimic of the ion transport within a cell membrane, has yet to be realized. Herein, we report the electrostatic gating of proton transport within aligned mesoporous silica thin film. It is observed that surface-charge-mediated transport is dominant at low proton concentrations. We have further demonstrated that the proton conduction can be actively modulated by two-fourfold with a gate voltage as low as 1V. Such artificial gatable ion transport media could have potential applications in nanofluidic chemical processors, biomolecular separation and electrochemical energy conversion.

  1. Intercellular transport.

    PubMed

    Thatcher, Jack D

    2013-04-16

    These animations depict generalities of intercellular transport. The animation called "permeability and transport" demonstrates the permeability of four classes of molecules. The "gap junctions" animation shows how these intercellular complexes exclude large factors while they allow small factors to diffuse between cells. These animations serve as useful resources for any collegiate-level course that describes these processes. Courses that might use them include biochemistry, biophysics, cell biology, introductory biology, and physiology.

  2. Les inconvénients de perdre du poids

    PubMed Central

    Bosomworth, N. John

    2012-01-01

    Résumé Objectif Explorer les raisons pour lesquelles la perte de poids à long terme échoue la plupart du temps et évaluer les conséquences de diverses trajectoires pondérales, y compris la stabilité, la perte et le gain. Source des données Les études qui évaluent les paramètres pondéraux dans la population sont en majorité observationnelles. Des données probantes de niveau I ont été publiées pour évaluer l’influence des interventions relatives au poids sur la mortalité et la qualité de vie. Message principal Seulement un petit pourcentage des personnes qui désirent perdre du poids réussissent à le faire de manière durable. La mortalité est la plus faible chez les personnes se situant dans la catégorie de poids élevé-normal et surpoids. La trajectoire pondérale la plus sécuritaire est la stabilité du poids avec une optimisation de la condition physique et métabolique. Il est démontré que la mortalité est plus faible chez les personnes ayant des comorbidités reliées à l’obésité si elles perdent du poids. Il est aussi établi que la qualité de vie sur le plan de la santé est meilleure chez les personnes obèses qui perdent du poids. Par contre, la perte de poids chez une personne obèse autrement en santé est associée à une mortalité accrue. Conclusion La perte de poids est recommandable seulement chez les personnes qui ont des comorbidités reliées à l’obésité. Les personnes obèses en santé qui veulent perdre du poids devraient être informées qu’il peut y avoir des risques à le faire. Une stratégie qui se traduit par un indice de masse corporelle stable avec une condition physique et métabolique optimisée, peu importe le poids, est l’option d’intervention la plus sécuritaire en ce qui concerne le poids.

  3. Participation des médecins généralistes de la province de Benimellal (Maroc) dans le dépistage du cancer du col

    PubMed Central

    Nani, Samira; Benallal, Mohamed; Hassoune, Samira; Kissi, Dounia; Maaroufi, Abderrahmane

    2013-01-01

    Introduction Au Maroc, chaque année il y aurait environ 2000 nouveaux cas de cancer du col et les 2/3 des cas sont pris en charge à un stade très avancé. Nous avons mené une étude transversale, exhaustive incluant les 71 médecins généralistes exerçant dans les établissements de soins de santé de base du secteur public et privé de la province de Benimellal. Le but était d’évaluer leurs connaissances et leur participation au dépistage du cancer du col. Méthodes Nous avons mené une étude transversale, exhaustive incluant les 71 médecins généralistes exerçant dans les établissements de soins de santé de base du secteur public et privé de la province de Benimellal. Le but était d’évaluer leurs connaissances et leur participation au dépistage du cancer du col. Résultats Le niveau de connaissance était relativement modeste, 22 médecins généraliste avaient répondu à la question sur l'incidence du cancer du col au Maroc, Parmi eux (81,8%) avaient donné une réponse incorrecte. L'Herpes Papilloma virus comme facteur de risque du cancer du col a été identifié par seulement 21% des médecins généralistes. La participation au dépistage était également défaillante, 92,8% n'avaient jamais pratiqué le FCV chez leurs patientes à cause principalement du manque de formation (95,5%). Conclusion Les résultats montrent la nécessité d'améliorer les connaissances théoriques et pratique des médecins généralistes concernant le dépistage du cancer du col. PMID:23785557

  4. Transport and metabolism of glucose and arabinose in Bifidobacterium breve.

    PubMed

    Degnan, B A; Macfarlane, G T

    1993-01-01

    Glucose was required for the transport of arabinose into Bifidobacterium breve. The non-metabolisable glucose analogue 2-deoxy-D-glucose (2-DG) did not facilitate assimilation of arabinose. Studies using D-[U-14C]-labelled arabinose showed that it was fermented to pyruvate, formate, lactate and acetate, whereas the principal metabolic products of D-[U-14C]-labelled glucose were acetate and formate. In contrast to glucose, arabinose was not incorporated into cellular macromolecules. A variety of metabolic inhibitors and inhibitors of sugar transport (proton ionophores, metal ionophores, compounds associated with electron transport) were used to investigate the mechanisms of sugar uptake. Only NaF, an inhibitor of substrate level phosphorylation, and 2-DG inhibited glucose assimilation. 2-DC had no effect on arabinose uptake, but NaF was stimulatory. High levels of phosphorylation of glucose and 2-DC by PEP and to a lesser degree, ATP were seen in phosphoenolpyruvate: phosphotransferase (PEP:PTS) assays. These data together with strong inhibition of glucose uptake by NaF suggest a role for phosphorylation in the transport process. Arabinose uptake in B. breve was not directly dependent on phosphorylation or any other energy-linked form of transport but may be assimilated by glucose-dependent facilitated diffusion.

  5. Rupture simultanée du ligament croisé antérieur et du ligament patellaire: à propos d'un cas

    PubMed Central

    Achkoun, Abdessalam; Houjairi, Khalid; Quahtan, Omar; Hassoun, Jalal; Arssi, Mohamed; Rahmi, Mohamed; Garch, Abdelhak

    2016-01-01

    La rupture simultanée du tendon rotulien et du ligament croisé antérieur est une lésion relativement rare. Son diagnostic peut facilement manquer lors de l'examen initial. Les options de traitement incluent la réparation immédiate du tendon rotulien avec soit la reconstruction simultanée ou différée de ligament croisé antérieur. Nous rapportons le cas d'une rupture combinée du tendon rotulien et du ligament croisé antérieur chez un jeune footballeur de 22 ans. Une approche de traitement en deux temps a été effectuée avec un excellent résultat fonctionnel. PMID:27366288

  6. DuPont cuts energy consumption 8% -- for starters

    SciTech Connect

    Wiseman, K.

    1998-07-01

    DuPont`s Corporate Energy Leadership Team (CELT) faced a difficult challenge at its inception in 1991--reducing the industry giant`s $900 million annual domestic energy bill. Seven years later, DuPont`s annual energy costs are down to $800 million, and energy consumption has shrunk by more than 8%. The team is on track toward future reduction goals. Key to persuading the company was the team`s 1992 Jump Start commitment to reduce out-of-pocket energy expenditures immediately. Over a four-month period, the goal was to save $6 million out-of-pocket on energy costs. The company actually ended up doubling that, saving over $12 million. The greatest savings--26% of the total--came from shutting down spare or unneeded equipment. Equipment tune-ups to improve performance and renegotiation of fuel contracts also lowered energy costs. The paper discusses how it was done.

  7. A Conversation with Lee Alvin DuBridge - Part I

    NASA Astrophysics Data System (ADS)

    Goodstein, Judith R.

    Physicist Lee A. DuBridge became president of the California Institute of Technology in 1946. In this interview he recalls the immediate problems he faced, including his dealings with Robert A. Millikan, whom he replaced as chief administrator of the institute; institute financing and inadequate salaries. DuBridge also talks about the advent of federal support for peacetime science and Millikan's distaste for it; his close working relationship with Robert F. Bacher, who came to the institute in 1949 as chairman of the Division of Physics, Mathematics, and Astronomy; his recollections of the meteorologist Irving P. Krick, the physicist Alexander Goetz, and the chemist Linus Pauling; and his attempts to build up the Humanities Division.

  8. Du Pont Classifications of 2 ASAS-SN Supernovae

    NASA Astrophysics Data System (ADS)

    Shappee, Benjamin J.; Prieto, J. L.; Rich, J.; Madore, B.; Poetrodjojo, Henry; D'Agostino, Joshua

    2016-09-01

    We report optical spectroscopy (range 370-910 nm) of two supernovae discovered by the All-Sky Automated Survey for Supernovae (ASAS-SN; Shappee et al. 2014, ApJ, 788, 48) using the du Pont 2.5-m telescope (+ WFCCD) at Las Campanas Observatory on Aug. 30 and Sep. 1 2016 UT. We performed a cross-correlation with a library of supernova spectra using the "Supernova Identification" code (SNID; Blondin and Tonry 2007, Ap.J.

  9. Du Pont Classifications of 4 ASAS-SN Supernovae

    NASA Astrophysics Data System (ADS)

    Morrell, N.; Shappee, Benjamin J.

    2016-08-01

    We report optical spectroscopy (range 370-910 nm) of four supernovae discovered by the All-Sky Automated Survey for Supernovae (ASAS-SN; Shappee et al. 2014, ApJ, 788, 48) using the du Pont 2.5-m telescope (+ WFCCD) at Las Campanas Observatory on July 31 and Aug. 01 2016 UT. We performed a cross-correlation with a library of supernova spectra using the "Supernova Identification" code (SNID; Blondin and Tonry 2007, Ap.J.

  10. DuPage County chilled water storage project

    SciTech Connect

    Grumman, D.L.

    1998-10-01

    Between 1992 and 1995, the DuPage County Governmental Center in Wheaton, Illinois, commissioned a detailed analysis of its chilled water plant and distribution system, as well as its future needs and options for meeting those needs. The result was a 10,000 ton-hour (35,170 kWh) chilled water storage tank with associated components and controls. This paper describes that process and the system that resulted.

  11. DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ.

    PubMed

    Cardoso-Weide, L C; Cardoso-Penha, R C; Costa, M W; Ferreira, A C F; Carvalho, D P; Santisteban, P S

    2015-03-01

    The production of H2O2, which is essential to thyroid hormone synthesis, involves two NADPH oxidases: dual oxidases 1 and 2 (DuOx1 and DuOx2). A functional study with human DuOx genes and their 5'-flanking regions showed that DuOx1 and -2 promoters are different from thyroid-specific gene promoters. Furthermore, their transcriptional activities are not restricted to thyroid cells. While regulation of Tg (thyroglobulin) and TPO (thyroperoxidase) expression have been extensively studied, DuOx2 promoter regulation by hormones and transcriptional factors need to be more explored. Herein we investigated the role of TSH, insulin and insulin-like growth factor 1 (IGF-1), as well as the cAMP effect on DuOx2 promoter (ptx41) activity in transfected rat thyroid cell lines (PCCL3). We also assessed DuOx2 promoter activity in the presence of transcriptional factors crucial to thyroid development such as TTF-1 (thyroid transcription factor 1), PAX8, CREB, DREAM, Nkx2.5 and the coactivator TAZ in HeLa and HEK 293T-transfected cells. Our results show that TSH and forskolin, which increase cAMP in thyroid cells, stimulated DuOx2 promoter activity. IGF-1 led to pronounced stimulation, while insulin induction was not statistically different from DuOx2 promoter basal activity. All transcriptional factors selected for this work and coactivator TAZ, except DREAM, stimulated DuOx2 promoter activity. Moreover, Nkx2.5 and TAZ synergistically increased DuOx2 promoter activity. In conclusion, we show that DuOx2 expression is regulated by hormones and transcription factors involved in thyroid organogenesis and carcinogenesis, reinforcing the importance of the control of H2O2 generation in the thyroid. PMID:25960956

  12. Une cause rare de plexopathie brachiale: une metastase d'un cancer du sein

    PubMed Central

    Maâroufi, Mustapha; Kamaoui, Imane; Boubbou, Meriem; Sqalli, Nadia; Tizniti, Siham

    2014-01-01

    Nous rapportons le cas d'une patiente de 50 ans ayant une histoire de cancer du sein et qui accuse une symptomatologie d'atteinte du plexus brachial. L'IRM montre une masse qui envahie le plexus brachial compatible avec une métastase. L'IRM est très utile pour le diagnostic et l'orientation thérapeutique des plexopathies brachiales chez les femmes présentant un cancer du sein PMID:25360196

  13. Une forme exceptionnelle de la luxation perilunaire du carpe

    PubMed Central

    Elouakili, Issam; Ouchrif, Younes; Najib, Abdeljaouad; Ouakrim, Redouane; Lamrani, Omar; Kharmaz, Mohammed; Ismael, Farid; Lahlou, Abdo; Elouadghiri, Mohammed; El Bardouni, Ahmed; Mahfoud, Mustapha; Berrada, Mohammed Saleh; El Yaccoubi, Mouradh

    2014-01-01

    Les luxations périlunaires (LPL) du carpe sont des lésions extrêmement rares, qui peuvent passer inaperçue en raison d'un tableau clinique souvent trompeur, des radiographies en profil non strict ou d'interprétation difficile. Nous rapportons l'observation d'une luxation périlunaire stade III selon la classification de Witvoët et Allieu chez un patient de 32 ans, il s'agit d'une forme encore plus rare voire exceptionnelle et qui peut induire de sérieux problèmes en raison de la sévérité des dommages ligamentaires et du risque de nécrose du semilunaire plus important dans ce type de lésions. Le traitement est toujours chirurgical et doit être réalisé dans les plus brefs délais afin d’éviter les complications. PMID:25404968

  14. La Carte du Ciel, histoire et actualité d'un projet scientifique international

    NASA Astrophysics Data System (ADS)

    Lamy, J.

    2008-06-01

    Cet ouvrage collectif analyse la genèse, le déploiement, l'abandon et les résurgences récentes de la Carte du Ciel. Au-delà de son échec avéré, la Carte du Ciel fut en effet le premier projet international astronomique de grande envergure, remarquable notamment par son organisation à l'échelle du globe. Bien plus que par son objet ou les techniques mobilisées pour sa réalisation, c'est par cette vision que la Carte du Ciel ouvre une nouvelle ère pour l'astronomie.

  15. A Coupled Modeling Approach for Root-Soil Interaction Processes Using DuMuX

    NASA Astrophysics Data System (ADS)

    Schröder, N.; Helmig, R.; Flemisch, B.; Koch, T.

    2015-12-01

    The water and nutrient uptake of plant roots in soils have a crucial influence on soil physical processes. The interacting processes between plant roots and soil are important for several agricultural problems, for example water management or leaching of pesticides. However, the coupled mechanisms of local soil and root water flow, transport of dissolved substances, root growth, and root uptake are difficult to measure and thus experimental data are rare. Numerical models can be used to understand these complex soil-root systems and help to analyze and interpret experimental measurements. The model approach presented here couples a root system and a soil model. Crucial for this approach is the 1D-3D grid coupling which combines a 1D network grid (root system) with the 3D soil grid. Based on that grid coupling, local processes are defined, for instance the local water uptake of a single root segment. Here, the interface conditions between roots and soil play a major role and we use local grid refinement strategies to better resolve these interface processes. This grid refinement of the 3D soil grid is based on the root network (1D grid) and adapts if root growth occurs. It offers the possibility to describe processes in the soil-plant continuum in a more physical manner avoiding empirical descriptions of root water uptake as a function of bulk matric potential, osmotic potential, root length density, and transpiration rate. Our coupling approach is included into the framework of DuMux, an open-source simulator for flow and transport processes in porous media. This implementation combines biological, chemical and physical processes in soil, inside roots, and at root-soil interfaces, and is contained in a sustainable and consistent framework for the implementation. We will show example simulations describing water flow, solute transport and root growth in a soil-root system.

  16. Pupil Transportation.

    ERIC Educational Resources Information Center

    Bete, Tim, Ed.

    1998-01-01

    Presents the opinions of four transportation experts on issues related to school buses. The experts respond to the following questions: will advertisements placed on buses be used to generate district revenue; will compressed natural gas or liquefied natural gas become standard fuel for school buses; and will school bus seat belts be mandatory and…

  17. Membrane Transport

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The selective movement and redistribution of ions and small organic molecules is essential for plant growth and cellular homeostasis. Because of this, plants have evolved numerous proteins that facilitate the transport of minerals, sugars, metabolites, and other compounds through the limiting membra...

  18. Connaissances des médecins généralistes de Mohammedia (Maroc) concernant le dépistage du cancer du sein

    PubMed Central

    Zine, Karima; Nani, Samira; Lahmadi, Imad Ait; Maaroufi, Abderrahmane

    2016-01-01

    Introduction Le cancer du sein représente un problème de santé publique majeur au Maroc. C'est le premier cancer chez la femme. L'objectif de ce travail était d'évaluer les connaissances des médecins généralistes (MG) en matière de dépistage du cancer du sein dans la préfecture de Mohammedia Maroc. Méthodes Nous avons mené une étude transversale, descriptive, exhaustive incluant les 97 MG exerçant dans les établissements de soins de santé de base du secteur public et privé de la province de Mohammedia. Résultats Le taux de participation était de 87%. L'âge moyen des MG était de 49,6 ± 8,1. Quatre-vingt pour cent (n=55) des MG ont donné une incidence incorrecte, 77,6% (n=85) ont reconnu l'existence d'un plan national de prévention et de contrôle du cancer (PNPCC) au Maroc, et 67,1 des MG ont rapporté l'existence d'un registre du cancer au Maroc. Le secteur d'activité était associé significativement avec les connaissances des MG sur le PNPCC et sur l'existence d'un guide de détection précoce du cancer du sein avec respectivement (p=0,003 et p=0,001). Une association significative entre l'ancienneté et l'existence d'un guide de détection précoce du cancer du sein et d'un registre du cancer du sein a été retrouvée avec (respectivement p=0,005 et p=0.002). Conclusion À la lumière de ces résultats il faudra renforcer les connaissances et les pratiques des MG par la promotion de la formation initiale et continue sur le dépistage. PMID:27800098

  19. Le cancer en Mauritanie : résultats sur 10 ans du registre hospitalier de Nouakchott

    PubMed Central

    Baba, Nacer Dine Ould Mohamed; Sauvaget, Catherine

    2013-01-01

    Le fardeau du cancer reste mal connu en Mauritanie. Il n'est basé que sur des extrapolations de l'incidence des cancers des pays avoisinants. Les données du registre de l'hôpital national permettent de décrire les cas avec un diagnostic histologique. Tous les cas de cancers enregistrés par le service d'anatomo-pathologie de l'hôpital national de Nouakchott de 2000 à 2009 ont été analysés. En 10 ans, 3305 prélèvements histologiques ont été analysés (hommes:42%, femmes:58%). Chez l'homme, le cancer le plus fréquemment analysé était le cancer de la peau (218 cas au total, 189 cas en excluant mélanome), suivi de la prostate (203), des cancers digestifs (179, colorectal et ‘sophage), et des lymphomes (151). Chez la femme, un quart des biopsies était des cancers du sein (485), suivi du col utérin (344), de la sphère gynécologique (218, ovaire et corps utérin), et de la peau (114). Les cancers du foie, du poumon ou de la vessie étaient peu fréquents. Ces résultats ne reflètent pas l'incidence ni l'actuel fardeau du cancer en Mauritanie puisque de nombreux patients diagnostiqués avec un cancer ne reçoivent pas d'examen anatomopathologique. Si, comme dans les pays avoisinants du Maroc et du Mali, les cancers du col et du sein sont les pathologies les plus fréquentes chez la femme, la distribution des cancers chez l'homme dans ce registre hospitalier diffère des résultats des registres de population du Maroc et du Mali où les cancers du poumon, du foie, de la prostate et de la vessie dominent. PMID:23785554

  20. LNG transportation

    SciTech Connect

    Picard, J.

    1988-01-01

    In the beginning of 1965, the participants to the starting up of first French LNG transportation system between ARZEW and LE HAVRE were indeed pioneers when they started the cool-down of the three tanks of LE HAVRE, with a LNG freight delivered by old liberty-ship ''BEAUVAIS''. Could they forecast the development of LNG industry in FRANCE and in the world and imagine that modest 'JULES VERNE' and his two english brothers would have, 25 years later, 80 successors - more than five times as big, for the main part of them, that 12 liquefaction plants would be running in the world, supplying about twenty LNG terminals. For the first time, a country - FRANCE - can draw the lessons from the exploitation of the 3 LNG transportation systems during a long period. That is the subject of the present paper.

  1. Copper transport.

    PubMed

    Linder, M C; Wooten, L; Cerveza, P; Cotton, S; Shulze, R; Lomeli, N

    1998-05-01

    In adult humans, the net absorption of dietary copper is approximately 1 mg/d. Dietary copper joins some 4-5 mg of endogenous copper flowing into the gastrointestinal tract through various digestive juices. Most of this copper returns to the circulation and to the tissues (including liver) that formed them. Much lower amounts of copper flow into and out of other major parts of the body (including heart, skeletal muscle, and brain). Newly absorbed copper is transported to body tissues in two phases, borne primarily by plasma protein carriers (albumin, transcuprein, and ceruloplasmin). In the first phase, copper goes from the intestine to the liver and kidney; in the second phase, copper usually goes from the liver (and perhaps also the kidney) to other organs. Ceruloplasmin plays a role in this second phase. Alternatively, liver copper can also exit via the bile, and in a form that is less easily reabsorbed. Copper is also present in and transported by other body fluids, including those bathing the brain and central nervous system and surrounding the fetus in the amniotic sac. Ceruloplasmin is present in these fluids and may also be involved in copper transport there. The concentrations of copper and ceruloplasmin in milk vary with lactational stage. Parallel changes occur in ceruloplasmin messenger RNA expression in the mammary gland (as determined in pigs). Copper in milk ceruloplasmin appears to be particularly available for absorption, at least in rats. PMID:9587137

  2. Copper transport.

    PubMed

    Linder, M C; Wooten, L; Cerveza, P; Cotton, S; Shulze, R; Lomeli, N

    1998-05-01

    In adult humans, the net absorption of dietary copper is approximately 1 mg/d. Dietary copper joins some 4-5 mg of endogenous copper flowing into the gastrointestinal tract through various digestive juices. Most of this copper returns to the circulation and to the tissues (including liver) that formed them. Much lower amounts of copper flow into and out of other major parts of the body (including heart, skeletal muscle, and brain). Newly absorbed copper is transported to body tissues in two phases, borne primarily by plasma protein carriers (albumin, transcuprein, and ceruloplasmin). In the first phase, copper goes from the intestine to the liver and kidney; in the second phase, copper usually goes from the liver (and perhaps also the kidney) to other organs. Ceruloplasmin plays a role in this second phase. Alternatively, liver copper can also exit via the bile, and in a form that is less easily reabsorbed. Copper is also present in and transported by other body fluids, including those bathing the brain and central nervous system and surrounding the fetus in the amniotic sac. Ceruloplasmin is present in these fluids and may also be involved in copper transport there. The concentrations of copper and ceruloplasmin in milk vary with lactational stage. Parallel changes occur in ceruloplasmin messenger RNA expression in the mammary gland (as determined in pigs). Copper in milk ceruloplasmin appears to be particularly available for absorption, at least in rats.

  3. Luxation de l’épaule compliquée de paralysie du plexus brachial

    PubMed Central

    Lukulunga, Loubet Unyendje; Moussa, Abdou Kadri; Mahfoud, Mustapha; EL Bardouni, Ahmed; Berrada, Mohamed Saleh; El Yaacoubi, Moradh

    2014-01-01

    Les auteurs rapportent l'observation d'une paralysie totale du plexus brachial survenue trois mois après un épisode de luxation antéro-interne sous coracoïdienne associée à une fracture du trochiter chez une patiente âgée de 88 ans. PMID:25426187

  4. Prevalence of Autism Spectrum Phenomenology in Cornelia de Lange and Cri du Chat Syndromes

    ERIC Educational Resources Information Center

    Moss, Joanna F.; Oliver, Chris; Berg, Katy; Kaur, Gurmeash; Jephcott, Lesley; Cornish, Kim

    2008-01-01

    Autism spectrum disorder characteristics have not been evaluated in Cornelia de Lange and Cri du Chat syndromes using robust assessments. The Autism Diagnostic Observation Schedule and Social Communication Questionnaire were administered to 34 participants with Cornelia de Lange syndrome and a comparison group of 23 participants with Cri du Chat…

  5. Non-destructive analysis of DU content in the NIF hohlraums

    SciTech Connect

    Gharibyan, Narek; Moody, Ken J.; Shaughnessy, Dawn A.

    2015-12-16

    The advantage of using depleted uranium (DU) hohlraums in high-yield deuterium-tritium (DT) shots at the National Ignition Facility (NIF) is addressed by Döppner, et al., in great detail [1]. This DU based hohlraum incorporates a thin layer of DU, ~7 μm thick, on the inner surface along with a thin layer of a gold coating, ~0.7 μm thick, while the outer layer is ~22 μm thick gold. A thickness measurement of the DU layer can be performed using an optical microscope where the total DU weight can be computed provided a uniform DU layer. However, the uniformity of the thickness is not constant throughout the hohlraum since CAD drawing calculations of the DU weight do not agree with the computed values from optical measurements [2]. Therefore, a non-destructive method for quantifying the DU content in hohlraums has been established by utilizing gamma-ray spectroscopy. The details of this method, along with results from several hohlraums, are presented in this report.

  6. Association between Fatigue and Autistic Symptoms in Children with Cri du Chat Syndrome

    ERIC Educational Resources Information Center

    Claro, Anthony; Cornish, Kim; Gruber, Reut

    2011-01-01

    In the current study, the authors examined whether the fatigue level of children diagnosed with cri du chat syndrome was associated with the expression of autistic symptoms. Sixty-nine children with cri du chat syndrome were compared with 47 children with moderate to severe intellectual disabilities who did not differ on intellectual severity.…

  7. 78 FR 45556 - Notice of Intent to Prepare an Environmental Impact Statement for the Proposed Lac du Flambeau...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    ... Lac du Flambeau Band Fee-to-Trust Acquisition and Casino Project in Shullsburg, Wisconsin AGENCY... fee-to-trust transfer and casino project in the City of Shullsburg, Wisconsin, proposed by the Lac du... address and the caption specifying ``Scoping Comments for Proposed Lac du Flambeau Band Casino'' on...

  8. Transport quantique dans des nanostructures

    NASA Astrophysics Data System (ADS)

    Naud, C.

    2002-09-01

    Quantum transport in nanostructures This work is devoted to the design, fabrication and magnetotransport investigations of mesoscopic devices. The sample are obtain by e-beam lithography and the measurements are performed at low temperature in a dilution refrigerator in the presence of a magnetic field. We have used MBE grown AlGaAs/GaAs heterojonctions as starting material to fabricate a bipartite tiling of rhombus called mathcal{T}3 lattice. We observe for the first time large amplitude h/e oscillations in this network as compared to the one measured in square lattices of similar size. These oscillations are the signature of a recently predited localization phenomenon induced by Aharonov-Bohm interferences on this peculiar topology. For particular values of the magnetic field the propagation of the electron wave function is bounded in a small number of cells, called Aharonov-Bohm cages. More strikingly, at high magnetic field, h/2e oscillations appear whose amplitude can be much higher than the fundamental period. Their temperature dependence is similar to that of the h/e signal. These observations withdraw a simple interpretation in terms of harmonics generation. The origin of this phenomenon is still unclear and needs more investigations. The influence electrical width of the wire defining the network and so the rule of the number of channels can be studied using a gate deposited over the lattice. In particular we have measured the amplitude dependence of the h/e and h/2e signal versus the gate voltage. Ce travail est consacré à la réalisation d'échantillons mésoscopiques à partir de la lithographie électronique ainsi qu'à leur caractérisation à très basse température en magnétotransport. Nous avons pour cela exploité le gaz bidimensionnel d'électrons situé à l'interface d'une hétérojonction AlGaAs/GaAs pour réaliser un réseau de boucle d'une géométrie particulière baptisée la géométrie mathcal{T}3. Nous avons observé sur cette

  9. Cancer du sein historique à propos d'un cas!!! Comment réagir

    PubMed Central

    Laghzaoui, Omar

    2016-01-01

    Le cancer du sein localement avancé est une entité qui se fait rare dans les pays développés alors qu'on continue de recevoir des patientes à un stade avancé dans les pays africains. Nous proposant le cas d'une patiente intellectuelle prise en charge à l'hôpital militaire, Meknès, Maroc; qui a décelé la présence d'un nodule du sein droit par l'autopalpation mais elle n'a consulté le médecin que six mois après, dans un état historique de cancer du sein localement avancé. Le but de notre publication est donc de soulever les anomalies contemporaines aboutissant au retard diagnostic du cancer du sein et de proposer des solutions pour mieux sensibiliser la population. PMID:27642397

  10. The association between Cri du chat syndrome and dental anomalies.

    PubMed

    Hall, Charmaine; Hallett, Kerrod; Manton, David

    2014-01-01

    Cri du chat syndrome (CdcS), also known as 5p deletion syndrome is a genetic disorder caused by the partial deletion of chromatin from the short arm of chromosome 5. There is a paucity of literature on the dental manifestations in CdcS. The purposes of this report are to present the case of a nine-year-old girl with the syndrome, CdcS and to review its dental and clinical manifestations and their management in children. PMID:25514263

  11. Quantification du champ electromagnetique et description quantique de la generation du second harmonique a l'interieur d'une microcavite

    NASA Astrophysics Data System (ADS)

    Collette, Marc

    L'existence de particules virtuelles qui surgissent spontanement du vide pour disparaitre tres peu de temps apres leur apparition (les fluctuations du vide) trouve son origine dans le principe d'incertitude de Heisenberg. Par ailleurs, on sait que le phenomene de resonance par confinement explique l'amplification de l'intensite lumineuse a l'interieur d'une cavite ouverte aux frequences de resonances de celle-ci. C'est pourquoi le taux d'apparition des photons virtuels au sein des modes propres d'une cavite est lui aussi amplifie par le resonateur. Mathematiquement, cet effet quantique est decrit par l'existence d'un commutateur " anomal " entre les operateurs d'annihilation et de creation des photons. Nous decrivons les consequences de ce commutateur sur la generation du second harmonique optique (GSH), un processus photonique ou, dans un materiau optiquement non lineaire, deux photons de meme energie fusionnent pour n'en former qu'un seul. On commence ce travail avec un traitement complet et original sur la quantification du champ electromagnetique. On montre ensuite que les fluctuations du vide stimulent le signal de la GSH a l'interieur du milieu confine. Cependant, on constate aussi que les fluctuations du vide jouent le role d'un inhibiteur au declenchement du processus, c'est-a-dire que le seuil de la GSH augmente (il est superieur au seuil minimal de deux photons seulement). En conclusion, les mecanismes intimes de certains processus optiques non lineaires doivent etre reconsideres lorsqu'ils surviennent en presence d'un confinement electromagnetique.

  12. Properties, use and health effects of depleted uranium (DU): a general overview.

    PubMed

    Bleise, A; Danesi, P R; Burkart, W

    2003-01-01

    Depleted uranium (DU), a waste product of uranium enrichment, has several civilian and military applications. It was used as armor-piercing ammunition in international military conflicts and was claimed to contribute to health problems, known as the Gulf War Syndrome and recently as the Balkan Syndrome. This led to renewed efforts to assess the environmental consequences and the health impact of the use of DU. The radiological and chemical properties of DU can be compared to those of natural uranium, which is ubiquitously present in soil at a typical concentration of 3 mg/kg. Natural uranium has the same chemotoxicity, but its radiotoxicity is 60% higher. Due to the low specific radioactivity and the dominance of alpha-radiation no acute risk is attributed to external exposure to DU. The major risk is DU dust, generated when DU ammunition hits hard targets. Depending on aerosol speciation, inhalation may lead to a protracted exposure of the lung and other organs. After deposition on the ground, resuspension can take place if the DU containing particle size is sufficiently small. However, transfer to drinking water or locally produced food has little potential to lead to significant exposures to DU. Since poor solubility of uranium compounds and lack of information on speciation precludes the use of radioecological models for exposure assessment, biomonitoring has to be used for assessing exposed persons. Urine, feces, hair and nails record recent exposures to DU. With the exception of crews of military vehicles having been hit by DU penetrators, no body burdens above the range of values for natural uranium have been found. Therefore, observable health effects are not expected and residual cancer risk estimates have to be based on theoretical considerations. They appear to be very minor for all post-conflict situations, i.e. a fraction of those expected from natural radiation.

  13. Portage vaginal du streptocoque du groupe B chez la femme enceinte au niveau de la région de Marrakech

    PubMed Central

    Bassir, Ahlam; Dhibou, Hanane; Farah, Majdi; Mohamed, Lharmis; Amal, Addebous; Nabila, Souraa; Abderahim, Aboulfalah; Asmouki, Hamid; Soummani, Abderraouf

    2016-01-01

    Introduction Le streptocoque du groupe B est le principal agent impliqué dans les infections materno-fœtales, les septicémies et les méningites du nouveau-né à terme. L'objectif est de déterminer le taux de portage maternel du streptocoque du groupe B (SGB) à terme. Méthodes Un prélèvement vaginal a été réalisé de manière prospective chez 275 parturientes lors de l'entrée en salle d'accouchement sur une période de 06 mois. Résultats Le taux de portage était de 20,2%. Le portage était variable en fonction de l’âge gestationnel, il constitue 57.5% entre 37 et 38 semaines d'aménorrhée. Aucun des facteurs de risque n'a était statistiquement prédictif du portage maternel du SGB. Conclusion Le dépistage doit être réalisé à partir de 37 semaines d'aménorrhée, et comme le portage est intermittent, un prélèvement négatif ne garantirait pas que le portage soit négatif à l'accouchement. PMID:27222693

  14. Mobile Transporter

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The Space Shuttle Atlantis, STS-110 mission, deployed this railcar, called the Mobile Transporter, and an initial 43-foot section of track, the S0 (S-zero) truss, preparing the International Space Station (ISS) for future spacewalks. The first railroad in space, the Mobile Transporter will allow the Station's robotic arm to travel up and down the finished truss for future assembly and maintenance. The 27,000-pound S0 truss is the first of 9 segments that will make up the Station's external framework that will eventually stretch 356 feet (109 meters), or approximately the length of a football field. The completed truss structure will hold solar arrays and radiators to provide power and cooling for additional international research laboratories from Japan and Europe that will be attached to the Station. The Space Shuttle Orbiter Atlantis, STS-110 mission, was launched April 8, 2002 and returned to Earth April 19, 2002. STS-110's Extravehicular Activity (EVA) marked the first use of the Station's robotic arm to maneuver spacewalkers around the Station.

  15. Proton Transport

    NASA Technical Reports Server (NTRS)

    Pohorille, Andrew; DeVincenzi, Donald L. (Technical Monitor)

    2001-01-01

    The transport of protons across membranes is an essential process for both bioenergetics of modern cells and the origins of cellular life. All living systems make use of proton gradients across cell walls to convert environmental energy into a high-energy chemical compound, adenosine triphosphate (ATP), synthesized from adenosine diphosphate. ATP, in turn, is used as a source of energy to drive many cellular reactions. The ubiquity of this process in biology suggests that even the earliest cellular systems were relying on proton gradient for harvesting environmental energy needed to support their survival and growth. In contemporary cells, proton transfer is assisted by large, complex proteins embedded in membranes. The issue addressed in this Study was: how the same process can be accomplished with the aid of similar but much simpler molecules that could have existed in the protobiological milieu? The model system used in the study contained a bilayer membrane made of phospholipid, dimyristoylphosphatidylcholine (DMPC) which is a good model of the biological membranes forming cellular boundaries. Both sides of the bilayer were surrounded by water which simulated the environment inside and outside the cell. Embedded in the membrane was a fragment of the Influenza-A M$_2$ protein and enough sodium counterions to maintain system neutrality. This protein has been shown to exhibit remarkably high rates of proton transport and, therefore, is an excellent model to study the formation of proton gradients across membranes. The Influenza M$_2$ protein is 97 amino acids in length, but a fragment 25 amino acids long. which contains a transmembrane domain of 19 amino acids flanked by three amino acids on each side. is sufficient to transport protons. Four identical protein fragments, each folded into a helix, aggregate to form small channels spanning the membrane. Protons are conducted through a narrow pore in the middle of the channel in response to applied voltage. This

  16. Les astronomes de l'Empire du Milieu

    NASA Astrophysics Data System (ADS)

    Bonnet-Bidaud, J. M.

    2007-02-01

    Explosions d'étoiles, comètes, durée du jour, taches solaires, dans tous ces domaines, des observations chinoises datant de plusieurs siècles sont encore utilisées aujourd'hui. Pendant plus de 4000 ans, les astronomes de l'Empire du Milieu, organisés dans les grands observatoires impériaux, ont noté jour après jour, mois après mois, avec la plus grande précision tous les phénomènes célestes. Et ce sont des milliers de textes couvrant des périodes depuis au moins le Ve siècle avant l'ère moderne jusqu'à fin de la dernière dynastie des Qing en 1911, qui ont été conservés et dont une grande partie n'a pu encore être véritablement étudiée. Un véritable trésor, malheureusement très mal connu en Europe et, de façon incompréhensible, largement ignoré par l'histoire moderne des sciences.

  17. Anévrysme ventriculaire gauche et communication interventriculaire compliquant un infarctus du myocarde

    PubMed Central

    Belkhadir, Mohammed; MoutakiAllah, Younes; Raissouni, Zainab; Abdou, Abdessamad; Bamous, Mehdi; Nya, Fouad; Atmani, Noureddine; Houssa, Mahdi Ait; El Bekkali, Youssef; Boulahya, Abdellatif

    2014-01-01

    L'association d'une communication interventriculaire post infarctus du myocarde et d'un anévrysme du ventricule gauche chez un même patient est extrêmement rare et survient habituellement durant la première semaine qui suit un infarctus du myocarde. Nous rapportons le cas insolite d'un patient âgé de 63 ans, admis pour choc cardiogénique en rapport avec une communication inter ventriculaire apicale et un anévrysme ventriculaire gauche causés par un infarctus du myocarde antérieur. La correction chirurgicale a consisté en une fermeture du défect septal par un patch en dacron via une ventriculotomie gauche associée à une anévrysectomie et un mono pontage coronaire. Cette observation illustre d'une part la rareté de l'association communication inter ventriculaire-anévrysme ventriculaire gauche post infarctus du myocarde, et d'autre part l'efficacité du traitement chirurgical qui reste la seule option salvatrice pour cette pathologie. PMID:25328617

  18. Carcinome colloïde du sein: à propos d'un cas

    PubMed Central

    Laabadi, Kamilia; Jayi, Sofia; Alaoui, Fatimazohra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, My Abdelilah

    2013-01-01

    Nous rapportons le cas d'une tumeur colloïde du sein chez un homme. Cette situation rare interpelle par son mode de découverte. Nous avons pris en charge un homme de 60 ans atteint d'une lésion rétro-aréolaire droite classée cliniquement T4b N1 M0 et suspecte radiologiquement. L'analyse histologique (microbiopsie) a conclu à un carcinome colloïde muqueux associé à une petite composante canalaire classique de grade I de SBR du sein. Les traitements complémentaires associent mastectomie, curage, chimiothérapie, radiothérapie et hormonothérapie. Le cancer du sein est rare chez l'homme. Le carcinome colloïde est exceptionnel puisqu'il représente seulement 1 à 6% de l'ensemble des cancers du sein. Il est encore plus rare chez l'homme. Ces tumeurs touchent une population spécifique et ont un meilleur pronostic que les autres types prépondérant dans les cancers du sein chez l'homme. A travers cette observation et une revue de la littérature, nous essaierons de discuter les principales caractéristiques anatomo-cliniques et évolutives de cette forme rare du cancer du sein. PMID:24772222

  19. A systematic review of the oral and craniofacial manifestations of cri du chat syndrome.

    PubMed

    Corcuera-Flores, José-Ramón; Casttellanos-Cosano, Lizett; Torres-Lagares, Daniel; Serrera-Figallo, María Ángeles; Rodríguez-Caballero, Ángela; Machuca-Portillo, Guillermo

    2016-07-01

    Cri du chat syndrome is an autosomal disorder. Because it affects few people in the population it is considered a rare disease, yet it is one of the most common autosomal chromosomal syndromes in humans. It entails pathognomonic alterations that affect the craniofacial and oral anatomy of patients. The aim of this study is to review these craniofacial and oral abnormalities in patients with Cri du chat syndrome. The PubMed Medline database was searched using two different strategies. First, we used "Dentistry" and "Cri du chat" as keywords; second, we used "Cri du chat" and "craniofacial." Seven articles in which the main orofacial and cranio-skeletal characteristics of patients with Cri du chat syndrome were described were selected according to the inclusion and exclusion criteria. Cri du Chat syndrome entails pathognomonic characteristics in the craniofacial area (epicanthus, short philtrum, and wide nasal bridge), the oral area (mandibular retrognathism and anterior open bite) and the cranial region (alterations at the cranial base angle and a small upper airway). However, more studies on larger samples are needed to specify the orofacial and craniofacial characteristics of patients with Cri du chat syndrome more accurately. Clin. Anat. 29:555-560, 2016. © 2015 Wiley Periodicals, Inc. PMID:26457586

  20. The Contributions of Chemistry and Transport to Low Arctic Ozone in March 2011 Derived from Aura MLS Observations

    NASA Technical Reports Server (NTRS)

    Strahan, S. E.; Douglass, A. R.; Newman, P. A.

    2012-01-01

    Stratospheric and total columns of Arctic O3 (63-90 N) in late March 2011 averaged 320 and 349 DU, respectively. These values are 74 DU lower than averages for the previous 6 years. We use Aura MLS O3 observations to quantify the roles of chemistry and transport and find there are two major reasons for low O3 in March 2011: heterogeneous chemical loss and a late final warming that delayed the resupply of O3 until April. Daily vortex-averaged partial columns in the lowermost stratosphere (p greater than 133 hPa) and middle stratosphere (p less than 29 hPa) are unaffected by local heterogeneous chemistry and show a near total lack of transport into the vortex between late January and late March, contributing to the observed low column. The lower stratospheric (LS) column (133-29 hPa) is affected by both heterogeneous chemistry and transport. Low interannual variability of Aura MLS 0 3 columns and temperature inside the Arctic vortex (2004-2011) shows that the transport contribution to vortex O3 in fall and early winter is nearly the same each year. The descent of MLS N2O vortex profiles in 2011 provides an estimate of O3 transported into the LS column during late winter. By quantifying the role of transport we determine that PSC-driven chemical loss causes 80 (plus or minus 10) DU of vortex-averaged O3 loss by late March 2011. Without heterogeneous chemical loss, March 2011 vortex O3 would have been 40 DU lower than normal due to the late final warming and resupply of O3 which did not occur until April.

  1. Localisation inhabituelle de la tuberculose: ostéoarthrite tuberculose du pouce

    PubMed Central

    Mortaji, Aziz; Koulali, Khalid; Galuia, Farid

    2014-01-01

    L'ostéoarthrite tuberculose est rare au niveau des doigts. Nous rapportons une observation d'atteinte du pouce chez un patient de 55 ans. Il avait présenté une tuméfaction douloureuse du pouce droit suite à un traumatisme du pouce. L’étude bactériologique et une biopsie avaient permis de confirmer le diagnostic. Un traitement antibacillaire de 12 mois avait donné des résultats satisfaisants. Les particularités de la prise en charge sont discutées par rapport aux données de la littérature. PMID:25932075

  2. Détermination de régimes transitoires des moteurs à induction par une nouvelle méthode de couplage des champs magnétiques du stator et du rotor

    NASA Astrophysics Data System (ADS)

    Bock, J. P.; Laporte, B.; Vinsard, G.

    1995-10-01

    A model allowing the effective computation of the transient behaviour of deep squirrel cage induction motors is detailed. The principle of the model is that the coupling between the rotor and the stator is made only by the fundamental space harmonic, the other harmonics are forced to vanish through the air gap. The main interest is that in the time step method only the fundamental space harmonic has to be transferred, which allows larger steps than in a punctual transfer. This method can be used when non linearities exist but it is detailed in the paper in the linear case. Nous présentons la modélisation d'un moteur à induction à cage profonde dont la vitesse est donnée et que l'on alimente, à partir d'un instant donné, par des courants qui sont des fonctions connues du temps. Les champs statoriques et rotoriques sont couplés par leur premier harmonique d'espace. L'intérêt de cette méthode est que seul le premier harmonique d'espace est transporté dans le suivi simultané du mouvement et de l'évolution des courants, ce qui autorise des rotations élémentaires plus importantes et donc un temps de calcul nettement réduit. La méthode, généralisable au cas non linéaire, est développée ici dans le cas linéaire.

  3. Polymorphisme de l'apolipoprotéine E dans la population du nord du Maroc: fréquence et influence sur les paramètres lipidiques

    PubMed Central

    Benyahya, Fatiha; Barakat, Amina; Ghailani, Naima; Bennani, Mohcine

    2013-01-01

    Introduction L'objectif de ce travail est de déterminer les fréquences alléliques et génotypiques des sites polymorphes situés dans le gène de l'apolipoprotéine E (apo E) ainsi que leur impact sur les paramètres cliniques et lipidiques dans un échantillon de la population du nord du Maroc cliniquement diagnostiqué ADH. Méthodes Le génotype de l'apo E a été analysé par séquençage direct chez 46 patients cliniquement diagnostiqués ADH selon les critères standards. Résultats Les fréquences des allèles epsilon 3, epsilon 2 et epsilon 4 ont été respectivement 78.3%, 2.2% et 19.6%. La fréquence de l'allèle epsilon 4 est très élevée chez la population du nord du Maroc en comparaison avec les populations des autres régions marocaines. Elle est similaire à celle rapportée dans les pays de l'Europe du nord. Les taux du cholestérol total, du cholestérol LDL ainsi que la présence des xanthomes et les maladies cardiovasculaires ne différent pas entre les génotypes de l'apoE. En revanche, les résultats ont montré une influence de l'allèle epsilon4 sur le taux des triglycérides chez les sujets obèses. Conclusion Le génotype de l'apoE ne peut expliquer le phénotype clinique et biochimique présenté par des patients du Nord du Maroc cliniquement diagnostiqués ADH. PMID:24396563

  4. Proceedings of a workshop on uses of depleted uranium in storage, transportation and repository facilities

    SciTech Connect

    1997-12-31

    A workshop on the potential uses of depleted uranium (DU) in the repository was organized to coordinate the planning of future activities. The attendees, the original workshop objective and the agenda are provided in Appendices A, B and C. After some opening remarks and discussions, the objectives of the workshop were revised to: (1) exchange information and views on the status of the Department of Energy (DOE) activities related to repository design and planning; (2) exchange information on DU management and planning; (3) identify potential uses of DU in the storage, transportation, and disposal of high-level waste and spent fuel; and (4) define the future activities that would be needed if potential uses were to be further evaluated and developed. This summary of the workshop is intended to be an integrated resource for planning of any future work related to DU use in the repository. The synopsis of the first day`s presentations is provided in Appendix D. Copies of slides from each presenter are presented in Appendix E.

  5. Transport de paires EPR dans des structures mesoscopiques

    NASA Astrophysics Data System (ADS)

    Dupont, Emilie

    Dans cette these, nous nous sommes particulierement interesses a la propagation de paires EPR1 delocalisees et localisees, et a l'influence d'un supraconducteur sur le transport de ces paires. Apres une introduction de cette etude, ainsi que du cadre scientifique qu'est l'informatique quantique dans lequel elle s'inscrit, nous allons dans le chapitre 1 faire un rappel sur le systeme constitue de deux points quantiques normaux entoures de deux fils supraconducteurs. Cela nous permettra d'introduire une methode de calcul qui sera reutilisee par la suite, et de trouver egalement le courant Josephson produit par ce systeme transforme en SQUID-dc par l'ajout d'une jonction auxiliaire. Le SQUID permet de mesurer l'etat de spin (singulet ou triplet), et peut etre forme a partir d'autres systemes que nous etudierons ensuite. Dans le chapitre 2, nous rappellerons l'etude detaillee d'un intricateur d'Andreev faite par un groupe de Bale. La matrice T, permettant d'obtenir le courant dans les cas ou les electrons sont separes spatialement ou non, sera etudiee en detail afin d'en faire usage au chapitre suivant. Le chapitre 3 est consacre a l'etude de l'influence du bruit sur le fonctionnement de l'intricateur d'Andreev. Ce bruit modifie la forme du courant jusqu'a aboutir a d'autres conditions de fonctionnement de l'intricateur. En effet, le bruit present sur les points quantiques peut perturber le transport des paires EPR par l'intermediaire des degres de liberte. Nous montrerons que, du fait de l'"intrication" entre la charge de la paire et le bruit, la paire est detruite pour des temps longs. Cependant, le resultat le plus important sera que le bruit perturbe plus le transport des paires delocalisees, qui implique une resonance de Breit-Wigner a deux particules. Le transport parasite n'implique pour sa part qu'une resonance de Breit-Wigner a une particule. Dans le chapitre 4, nous reviendrons au systeme constitue de deux points quantiques entoures de deux fils

  6. Robotic transportation.

    PubMed

    Lob, W S

    1990-09-01

    Mobile robots perform fetch-and-carry tasks autonomously. An intelligent, sensor-equipped mobile robot does not require dedicated pathways or extensive facility modification. In the hospital, mobile robots can be used to carry specimens, pharmaceuticals, meals, etc. between supply centers, patient areas, and laboratories. The HelpMate (Transitions Research Corp.) mobile robot was developed specifically for hospital environments. To reach a desired destination, Help-Mate navigates with an on-board computer that continuously polls a suite of sensors, matches the sensor data against a pre-programmed map of the environment, and issues drive commands and path corrections. A sender operates the robot with a user-friendly menu that prompts for payload insertion and desired destination(s). Upon arrival at its selected destination, the robot prompts the recipient for a security code or physical key and awaits acknowledgement of payload removal. In the future, the integration of HelpMate with robot manipulators, test equipment, and central institutional information systems will open new applications in more localized areas and should help overcome difficulties in filling transport staff positions.

  7. Robotic transportation.

    PubMed

    Lob, W S

    1990-09-01

    Mobile robots perform fetch-and-carry tasks autonomously. An intelligent, sensor-equipped mobile robot does not require dedicated pathways or extensive facility modification. In the hospital, mobile robots can be used to carry specimens, pharmaceuticals, meals, etc. between supply centers, patient areas, and laboratories. The HelpMate (Transitions Research Corp.) mobile robot was developed specifically for hospital environments. To reach a desired destination, Help-Mate navigates with an on-board computer that continuously polls a suite of sensors, matches the sensor data against a pre-programmed map of the environment, and issues drive commands and path corrections. A sender operates the robot with a user-friendly menu that prompts for payload insertion and desired destination(s). Upon arrival at its selected destination, the robot prompts the recipient for a security code or physical key and awaits acknowledgement of payload removal. In the future, the integration of HelpMate with robot manipulators, test equipment, and central institutional information systems will open new applications in more localized areas and should help overcome difficulties in filling transport staff positions. PMID:2208684

  8. Mechanisms controlling lateral and vertical porewater migration of depleted uranium (DU) at two UK weapons testing sites.

    PubMed

    Graham, Margaret C; Oliver, Ian W; MacKenzie, Angus B; Ellam, Robert M; Farmer, John G

    2011-04-15

    Uranium associations with colloidal and truly dissolved soil porewater components from two Ministry of Defence Firing Ranges in the UK were investigated. Porewater samples from 2-cm depth intervals for three soil cores from each of the Dundrennan and Eskmeals ranges were fractionated using centrifugal ultrafiltration (UF) and gel electrophoresis (GE). Soil porewaters from a transect running downslope from the Dundrennan firing area towards a stream (Dunrod Burn) were examined similarly. Uranium concentrations and isotopic composition were determined using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) and Multi-Collector-Inductively Coupled Plasma-Mass Spectrometry (MC-ICP-MS), respectively. The soils at Dundrennan were Fe- and Al-rich clay-loam soils whilst at Eskmeals, they were Fe- and Al-poor sandy soils; both, however, had similar organic matter contents due to the presence of a near-surface peaty layer at Eskmeals. These compositional features influenced the porewater composition and indeed the associations of U (and DU). In general, at Dundrennan, U was split between large (100kDa-0.2μm) and small (3-30kDa) organic colloids whilst at Eskmeals, U was mainly in the small colloidal and truly dissolved fractions. Especially below 10cm depth, association with large Fe/Al/organic colloids was considered to be a precursor to the removal of U from the Dundrennan porewaters to the solid phase. In contrast, the association of U with small organic colloids was largely responsible for inhibiting attenuation in the Eskmeals soils. Lateral migration of U (and DU) through near-surface Dundrennan soils will involve both large and small colloids but, at depth, transport of the smaller amounts of U remaining in the porewaters may involve large colloids only. For one of the Dundrennan cores the importance of redox-related processes for the re-mobilisation of DU was also indicated as Mn(IV) reduction resulted in the release of both Mn(II) and U(VI) into the truly

  9. Cirque du Monde en tant qu’intervention en santé

    PubMed Central

    Fournier, Cynthia; Drouin, Mélodie-Anne; Marcoux, Jérémie; Garel, Patricia; Bochud, Emmanuel; Théberge, Julie; Aubertin, Patrice; Favreau, Gil; Fleet, Richard

    2014-01-01

    Résumé Objectif Présenter le programme Cirque du Monde du Cirque du Soleil et son potentiel en tant qu’intervention en soins de santé de première ligne pour les médecins de famille. Sources des données Une revue de la littérature menée dans les bases de données PubMed, Cochrane Library, PsycINFO, La Presse, Eureka, Google Scholar et Érudit à l’aide des mots-clés circus, social circus, Cirque du Monde et Cirque du Soleil. Une initiative à Montréal nommée Espace Transition qui s’inspire directement de Cirque du Monde. Communication personnelle avec le conseiller principal en formation en cirque social du Cirque du Soleil. Sélection d’études Les 50 premiers articles ou sites Internet répertoriés pour chaque mot-clé dans chacune des bases de données ciblées ont été révisés sur la base des titres et des résumés, s’il s’agissait d’un article, ou sur la base du titre et du contenu de la page, s’il s’agissait d’une page Internet. Ensuite, les articles et les sites Internet qui étudiaient un aspect du cirque social ou qui présentaient une intervention impliquant le cirque étaient retenus pour une révision. Aucune contrainte d’année de publication n’a été appliquée étant donné qu’on cherchait une littérature générale sur le cirque social. Synthèse Aucun article n’a été trouvé sur le cirque social en tant qu’intervention en santé. Nous avons trouvé une étude sur l’utilisation du cirque en tant qu’intervention en milieu scolaire. Cette étude a démontré une augmentation de l’estime personnelle des enfants grâce à l’intervention. Nous avons trouvé une étude sur l’utilisation du cirque en tant qu’intervention sur une réserve amérindienne. Cette étude présente des résultats qualitatifs non spécifiques au programme du cirque social. Les autres articles répertoriés n’étaient que des descriptions du cirque social. Un site web concernant l’utilisation du cirque social pour

  10. Consonant production and intelligibility in cri du chat syndrome.

    PubMed

    Kristoffersen, Kristian E; Garmann, Nina Gram; Simonsen, Hanne Gram

    2014-10-01

    This article focuses on consonant productions by a group of children with cri du chat syndrome (CdCS) and examines how various aspects of these productions contribute to these children's overall intelligibility. Eight children and adolescents with CdCS participated in the study, and the following four questions were addressed: (1) What are the characteristic features of the consonant inventories of the subjects in terms of size and types of consonants; (2) how do the subjects render the consonant phonemes of the target language; (3) to what degree do the subjects produce target-like words; and (4) what is the relationship between consonant production and intelligibility? For the majority of our subjects, we found low proportions of correctly produced consonants, small consonant inventories with several recurrent types of deviant consonants, inaccuracy in realization of target phonemes and variable similarity to target words, all of which may contribute to reduced intelligibility. PMID:24689530

  11. Cri du chat syndrome: a series of five cases.

    PubMed

    Dangare, Harsha M; Oommen, Samuel P; Sheth, Amisha N; Koshy, Beena; Roshan, Reeba; Thomas, Maya M; Danda, Sumita; Srivastava, Vivi M

    2012-01-01

    The cri du chat syndrome (CdCS) is a chromosomal deletion syndrome associated with a partial deletion of the short (p) arm of chromosome 5. We describe five children who were diagnosed to have CdCS by conventional cytogenetic analysis. The deletion was at 5p15 in four patients, whereas the fifth had a larger, more proximal deletion at 5p14. Fluorescence in situ hybridization (FISH) analysis confirmed the deletion of the CdCS critical region at 5p15.2. All five children had global developmental delay and dysmorphism with microcephaly. The other clinical features were variable. Since the clinical diagnosis of CdCS may not always be evident because of the phenotypic heterogeneity, cytogenetic analysis is necessary to establish the diagnosis and confirm that the deletion involves the CdCS critical region. This will enable early intervention which plays an important role in improving the outcome. PMID:23455788

  12. Nondestructive Testing Qualification of Main Circulatory Tube Pipes DU 500

    SciTech Connect

    Tabakova, Bojana M.; Tzokov, Petio

    2004-07-01

    The criteria for safe operation of nuclear energetic installations is given a higher priority in the policy of Kozloduy Nuclear Power Plant. An efficient non-destructive inspection is the key point for the safe service. Kozloduy NPP keeps on making investments in equipment and qualification of specialists in this field. The processes of qualification of the NDT components, important for the nuclear and radiation safety, make considerable improvement in Kozloduy NPP, thanks to the accumulated in the years experience in the activities of NDT inspection qualification, and to the help of our partners Serco Assurance and the Institute of Rzes. The results obtained by ultrasonic non-destructive inspection of circulation tube mains DU 500 WWER 440 type are under discussion in this report. (authors)

  13. Restauration fonctionnelle du rachis : effet du niveau initial de douleur sur les performances des sujets lombalgiques chroniques

    PubMed Central

    Caby, Isabelle; Olivier, N; Mendelek, F; Kheir, R Bou; Vanvelcenaher, J; Pelayo, P

    2014-01-01

    HISTORIQUE : La lombalgie chronique est une douleur lombaire persistante d’origine multifactorielle. Le niveau de douleur initial reste faiblement utilisé pour analyser et comparer les réponses des patients lombalgiques au programme de reconditionnement. OBJECTIFS : Apprécier et évaluer les réponses des sujets lombalgiques chroniques très douloureux à une prise en charge dynamique et intensive. MÉTHODOLOGIE : 144 sujets atteints de lombalgie chronique ont été inclus dans un programme de restauration fonctionnelle du rachis de 5 semaines. Les sujets ont été classés en deux groupes de niveau de douleur: un groupe atteint de douleur sévère (n = 28) et un groupe atteint de douleur légère à modérée (n = 106). L’ensemble des sujets ont bénéficié d’une prise en charge identique comprenant principalement de la kinésithérapie, de l’ergothérapie, du reconditionnement musculaire et cardio-vasculaire ainsi qu’un suivi psychologique. Les paramètres physiques (flexibilité, force musculaire) et psychologiques (qualité de vie) ont été mesurés avant (T0) et après le programme (T5sem). RÉSULTATS : L’ensemble des performances physiques et fonctionnelles des sujets très douloureux sont moins bonnes et le retentissement de la lombalgie sur la qualité de vie, pour ces mêmes sujets, est majoré à T0. Toutes les différences significatives constatées à T0 entre les deux groupes s’effacent à T5sem. CONCLUSIONS : Les sujets lombalgiques chroniques très douloureux répondent favorablement au programme dynamique et intensif. L’intensité douloureuse de la lombalgie n’aurait pas d’effet sur les réponses au programme. La restauration fonctionnelle du rachis apporterait aux sujets la possibilité de mieux gérer leur douleur quel que soit son niveau. PMID:25299476

  14. Etude de quelques fonctionnelles du mouvement brownien et de certaines propriétés de la diffusion unidimensionnelle en milieu aléatoire

    NASA Astrophysics Data System (ADS)

    Monthus, Cécile

    This paper deals with functionals of Brownian motion that appear in various contexts, and with some properties of anomalous diffusion in a one-dimensional random environment. Section 2 explains why path integrals provide a powerful framework to compute probability distribution of functionals of Brownian motion. This approach is used to study winding properties of planar Brownian motion. Section 3 is devoted to an exponential functional of Brownian motion, which arise in particular in the study of transport properties of classical diffusion in a one-dimensional disordered system of finite length. This functional belongs to the field of multiplicative stochastic processes. Cet article porte sur l'étude des distributions de probabilité de quelques fonctionnelles du mouvement brownien qui interviennent dans divers contextes physiques. Le paragraphe 2 présente une méthode d'intégrale de chemin qui relieles distributions de probabilité de certaines fonctionnelles du mouvement brownien, à des fonctions de Green euclidiennes de la mécanique quantique. Cette approche permet notamment d'étudier certaines propriétés d'enroulementdu mouvement brownien plan, qu'il soit libre ou soumis à l'action d'un potentiel extérieur. Les fonctions d'échelle et les formes des lois asymptotiques à grand temps de l'enroulement autour d'un point dépendent des propriétés spectrales de basse énergied'une famille d'hamiltoniens contenant un potentiel vecteur de type Aharonov-Bohm.Le paragraphe 3 a pour l'objet l'étude de la loi de probabilité d'une fonctionnelle exponentielle du mouvement brownien qui intervient dans le cadnG de la diffusion unidimensionnelle aléatoire. Celle-ci apparaît notamment lorsque l'on s'intéresse à la distribution du flux de particules quitraverse un échantillon désordonné de taille finie, lorsque les particules diffusent classiquement, sous l'action d'une force aléatoire gelée distribuée comme un bruit blanc gaussien. Le spectre de

  15. 76 FR 33401 - Environmental Impact Statement: Cook and DuPage Counties, Illinois

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... will be prepared for the Elgin O'Hare--West Bypass in Cook and DuPage Counties, Illinois. FOR FURTHER...-- West Bypass. The study area for the EIS is along the Elgin-O'Hare Expressway/Thorndale Avenue...

  16. Lymphome malin non hodgkinien du cavum: protocoles thérapeutiques et facteurs pronostiques

    PubMed Central

    Ouraini, Saloua; Nakkabi, Ismail; Benariba, Fouad

    2015-01-01

    Le lymphome malin non hodgkinien est une entité histologique rare parmi les cancers du cavum, la plupart des tumeurs du nasopharynx étant des carcinomes indifférenciés ou Undifferencied Carcinoma of Nasopharyngeal Type (UCNT); Il pose souvent un problème de diagnostic positif clinique et histologique. La symptomatologie est généralement peu spécifique et la démarche étiologique repose sur la biopsie du cavum faite à l'examen endoscopique avec examen immuno-histochimique. Nous rapportons le cas d'un lymphome non hodgkinien avec atteinte du nasopharynx, l'analyse anatomopathologique est en faveur d'un lymphome malin non hodgkinien de phénotype B. Les aspects cliniques, radiologiques, histologiques et thérapeutiques sont décrits. PMID:26889334

  17. ON NONLINEAR EQUATIONS OF THE FORM F(x,\\, u,\\, Du,\\, \\Delta u) = 0

    NASA Astrophysics Data System (ADS)

    Soltanov, K. N.

    1995-02-01

    The Dirichlet problem for equations of the form F(x,\\, u,\\, Du,\\, \\Delta u) = 0 and also the initial boundary value problem for a parabolic equation with a nonlinearity are studied.Bibliography: 11 titles.

  18. Une angiocholite secondaire à un thrombus tumoral d'une tumeur neuroendocrine primitive du foie

    PubMed Central

    Baba, Hicham; Allaoui, Mohamed; Elfahssi, Mohammed; Bounaim, Ahmed; Ali, Abdelmounaim Ait; Oukabli, Mohamed; Sair, Khalid; Zentar, Aziz

    2015-01-01

    Nous rapportons le cas exceptionnel d'une patiente de 54 ans prise en charge pour une angiocholite due à un thrombus tumoral, d'une tumeur neuroendocrine primitive (TNE Ive) du foie, dans la voie biliaire principale. PMID:26966504

  19. Transporting particulate material

    DOEpatents

    Aldred, Derek Leslie; Rader, Jeffrey A.; Saunders, Timothy W.

    2011-08-30

    A material transporting system comprises a material transporting apparatus (100) including a material transporting apparatus hopper structure (200, 202), which comprises at least one rotary transporting apparatus; a stationary hub structure (900) constraining and assisting the at least one rotary transporting apparatus; an outlet duct configuration (700) configured to permit material to exit therefrom and comprising at least one diverging portion (702, 702'); an outlet abutment configuration (800) configured to direct material to the outlet duct configuration; an outlet valve assembly from the material transporting system venting the material transporting system; and a moving wall configuration in the material transporting apparatus capable of assisting the material transporting apparatus in transporting material in the material transporting system. Material can be moved from the material transporting apparatus hopper structure to the outlet duct configuration through the at least one rotary transporting apparatus, the outlet abutment configuration, and the outlet valve assembly.

  20. Transporting Handicapped Students.

    ERIC Educational Resources Information Center

    Turner, Dayton Ray

    The book presents guidelines for adaptive transportation measures for handicapped students. Part 1 considers the transportation cycle as a means to evaluate individual student competencies at all logical points during the transportation experience. The transportation cycle is reviewed from deciding to transport the student to gaining access to…

  1. A yeast artificial chromosome contig of the critical region for cri-du-chat syndrome

    SciTech Connect

    Goodart, S.A.; Rojas, K.; Overhauser, J.

    1994-11-01

    Cri-du-chat is a chromosomal deletion syndrome characterized by partial deletion of the short arm of chromosome 5. The clinical symptoms include growth and mental retardation, microcephaly, hypertelorism, epicanthal folds, hyptonia, and a high-pitched monochromatic cry that is usually considered diagnostic for the syndrome. Recently, a correlation between clinical features and the extent of the chromosome 5 deletions has identified two regions of the short arm that appear to be critical for the abnormal development manifested in this syndrome. Loss of a small region in 5p15.2 correlates with all of the clinical features of cri-du-chat with the exception of the cat-like cry, which maps to 5p15.3. Here the authors report the construction of a YAC contig that spans the chromosomal region in 5p15.2 that plays a major role in the etiology of the cri-du-chat syndrome. YACs that span the 2-Mb cri-du-chat critical region have been identified and characterized. This YAC contig lays the groundwork for the construction of a transcriptional map of this region and the eventual identification of genes involved in the clinical features associated with the cri-du-chat syndrome. It also provides a new diagnostic tool for cri-du-chat in the shape of a YAC clone that may span the entire critical region. 24 refs., 4 figs., 2 tabs.

  2. Water-quality along selected flowpaths in the Prairie du Chien-Jordan aquifer, southeastern Minnesota

    SciTech Connect

    Smith, S.E. )

    1994-04-01

    The Prairie du Chien-Jordan aquifer in southeastern Minnesota is comprised of the dolomitic Prairie du Chien Group and the underlying Jordan Sandstone. Differences in water quality between the Prairie du Chien and the Jordan parts of the aquifer were investigated by sampling 139 wells in six study areas within Hennepin, Dakota, and Olmsted Counties. The study areas, which represent paths of groundwater flow through the aquifer, averaged 13 miles long and 3 miles wide. The wells were screened in the Jordan, Prairie du Chien, and overlying aquifers. Concentrations of tritium, nitrite plus nitrate nitrogen, and chloride were useful indicators of the actual and potential extent of human-related contamination of the aquifer. Differences in water quality were related to land use, aquifer permeability, thickness and lithology of overlying units, presence of confining units, flow path length, and well construction. Water samples from wells completed in the Jordan aquifer have lower tritium, nitrite plus nitrate nitrogen, and chloride concentrations than samples from wells completed in the overlying Prairie du Chien, St. Peter, and glacial drift aquifers. The distribution of these indicators on vertical sections of the aquifer, geochemical analysis of saturation indices (WATEQF), piper diagrams, and statistical analyses were used to analyze the hydrogeology and sensitivity to contamination of the Prairie du Chien-Jordan aquifer.

  3. Prise en charge des traumatismes graves du rein

    PubMed Central

    Lakmichi, Mohamed Amine; Jarir, Redouane; Sadiki, Bader; Zehraoui; Bentani; Wakrim, Bader; Dahami, Zakaria; Moudouni; Sarf, Ismail

    2015-01-01

    Les traumatismes graves du rein de grade III, IV et V selon la classification de l'Amercan Society for Surgery For Trauma (ASST) sont plus rares et se retrouvent dans 5% des cas en moyenne. Leur prise en charge est souvent délicate, nécessitant alors des centres expérimentés dotés de moyen adéquats d'imagerie (scanner spiralé). Cependant, durant ces dernières années, la prise en charge de ces traumatismes a évolué vers une attitude de moins en moins chirurgicale grâce à l’évolution des techniques de la radiologie interventionnelle, de l'endourologie et des moyens de surveillance aux urgences et de réanimation. L'objectif de cette étude est d’évaluer notre expérience dans la prise en charge des traumatismes rénaux de haut grade. Notre étude rétrospective porte sur 25 cas de traumatismes grave du rein de grade III, IV et V selon la classification de l'ASST, colligés entre Janvier 2002 et Juin 2009 au service d'urologie du centre Hospitalier Universitaire Mohammed VI, Université Cadi Ayyad de Marrakech, Maroc. Nous avons étudié les données épidémiologiques, les signes cliniques et biologiques à l'admission (état de choc hémorragique, taux d'hémoglobine), les données radiologiques (échographie et scanner), les lésions associées, la prise en charge thérapeutique et les complications. L’âge moyen de nos patients était de 24,9 ans 15 et 58 ans, avec une prédominance masculine (sex-ratio = 7, 3). Le rein droit était intéressé dans 15 cas (60%). Le traumatisme rénal était fermé dans 15 cas, et ouvert par arme blanche dans 10 cas. Huit patients se sont présentés en état de choc hémorragique (32%). Une anémie inférieur à 10g /100ml a été observée dans 10 cas (40%). L'uroscanner fait systématiquement à l'admission a retrouvé un grade III (10 cas), grade IV (13 cas) et grade V (2 cas). La prise en charge a consisté en une exploration chirurgicale avec néphrectomie chez 2 cas de Grade IV pour une instabilité h

  4. Moving beyond alternative fuel hype to decarbonize transportation

    NASA Astrophysics Data System (ADS)

    Melton, Noel; Axsen, Jonn; Sperling, Daniel

    2016-03-01

    In the past three decades, government, industry and other stakeholders have repeatedly been swept up with the ‘fuel du jour’, claiming that a particular alternative fuel vehicle (AFV) technology can succeed in replacing conventional gasoline-powered vehicles. However, AFV technologies have experienced relatively little success, with fossil fuels still accounting for about 95% of global transport energy use. Here, using the US as a case study, we conduct a media analysis to show how society’s attention has skipped among AFV types between 1980 and 2013, including methanol, natural gas, plug-in electric, hybrid electric, hydrogen and biofuels. Although our results provide no indication as to whether hype ultimately has a net positive or negative impact on AFV innovation, we offer several recommendations that governments can follow to move past hype to support significant AFV adoption and displace fossil fuel use in the transportation sector.

  5. Etude du champ magnetique dans les nuages moleculaires

    NASA Astrophysics Data System (ADS)

    Houde, Martin

    2001-12-01

    Ce travail est une étude du champ magnétique duns l'environnement circumstellaire des étoiles jeunes. Il a pour origine la certitude qu'avait l'auteur qu'il se devait d'être possible de détecter la présence d'un champ magnétique, et de possiblement le caractériser, par le biais d'observations de profils spectraux d'espèces moléculaires ioniques. Il en découle donc qu'un des buts principaux était de prouver que cela est effectivement possible. La thèse comporte alors des éléments théoriques et expérimentaux qui sont à la fois complémentaires et intimement liés. L'aspect théorique est basé sur l'interaction mutuelle que des particules neutres et chargées peuvent avoir l'une sur l'autre daps un plasma faiblement ionisé comme ceux existants daps les nuages moléculaires sites de formation stellaire. Il appert que la présence d'un champ magnétique a un effet direct sur le comportement des ions (via la force de Lorentz) et indirect sur les molécules neutres (via les nombreuses collisions entre les deux types de particules). Une telle interaction est, comme il est maintenant bien connu, présente dans les premières étapes de la formation dune étoile. Il s'agit bien sûr de la diffusion ambipolaire. Nous montrerons qu'il existe cependant un autre type de diffusion, jusqu'ici inconnue, qui se manifeste plus tard au tours de l'évolution des nuages moléculaires. Celle-ci peut avoir un effet dramatique sur l'apparence des profils spectraux (de rotation moléculaire) des espèces ioniques lorsque comparés à ceux qu'exhibent des espèces neutres coexistantes. Mais pour ce faire, il doit y avoir existence de mouvements organisés (des flots ou jets) de matière ou encore la présence de turbulence dans les régions considérées. Une distribution de vélocité du type maxwellienne ne révèlera pas la présence du champ magnétique. Les observations, qui ont pour but de confirmer la théorie, se situent dans le domaine des longueurs d

  6. Enhanced SO2 Concentrations Observed over Northern India: Role of Long-range Transport

    SciTech Connect

    Mallik, C.; Lal, S.; Naja, M.; Chand, Duli; Venkataramani, S.; Joshi, H.; Pant, P.

    2013-01-17

    Volcanic emissions and coal burning are among the major sources of SO2 over the continental environment. In this study, we show episodes of long-range transport of volcanic SO2 from Africa to Northern India using satellite observations. Monthly averaged SO2 from OMI were of the order of 0.6-0.9 DU during November, 2008 over the Indo-Gangetic Plain (IGP), which far exceeded background values (<0.3 DU) retrieved from observations across different locations over North India during 2005-2010. The columnar SO2 loadings were much higher on November 6 over most of the IGP and even exceeded 6 DU, a factor of 10 higher than background levels at some places. These enhanced SO2 levels were, however, not reciprocated in satellite derived NO2 or CO columns, indicating transport from a non-anthropogenic source of SO2. Backward trajectory analysis revealed strong winds in the free troposphere, which originated from the Dalaffilla volcanic eruption over the Afar region of Ethiopia during November 4-6, 2008. Wind streams and stable atmospheric conditions were conducive to the long-range transport of volcanic plume into the IGP. As most of the local aerosols over IGP region are below 3 km, a well separated layer at 4-5 km is observed from CALIPSO, most likely as a result of this transport. Apart from known anthropogenic sources, the additional transport of volcanic SO2 over the IGP region would have implications to air quality and radiation balance over this region.

  7. Role and mechanism of Twist1 in modulating the chemosensitivity of FaDu cells.

    PubMed

    Lu, Sumei; Yu, Liang; Mu, Yakui; Ma, Juke; Tian, Jiajun; Xu, Wei; Wang, Haibo

    2014-07-01

    Multidrug resistance (MDR) is one of the most important obstacles affecting the efficacy of chemotherapy treatments for numerous types of cancer. In the present study, we have demonstrated the possible function of Twist1 in the chemosensitivity of head and neck squamous cell carcinoma (HNSCC) and have identified that its mechanism maybe associated with MDR1/P-gp regulation. To investigate this, the hypopharyngeal cancer cell line, FaDu, and its MDR cell line induced by taxol, FaDu/T, were employed. Stable transfectants targeted to Twist1 overexpression and Twist1 silencing based on FaDu were also conducted. Morphological observation, flow cytometry, reverse transcription-polymerase chain reaction (RT-PCR), western blotting and laser scanning confocal microscope detection were utilized to detect the associations between Twist1 and the chemosensitivity of FaDu cells. Our results demonstrated that Twist1 and MDR1/P-gp were upregulated in FaDu/T cells in a MDR dose-dependent manner. The anti-apoptotic capabilities of FaDu/T cells were enhanced during MDR progression, with apoptosis-related proteins (Bcl-2, Bax, activated caspase-3 and caspase-9) changing to resist apoptosis. Twist1 overexpression decreased the sensitivity of cells to taxol as revealed by a significant increase in MDR1/P-gp and IC50 (P<0.05). This overexpression also enhanced the resistance to apoptosis, with apoptotic proteins changing to resist cell death, and inhibited Ca2+ release induced by taxol (P<0.05). Detections in Twist1 silencing cells also confirmed this result. This study provided evidence that alterations of Twist1 expression modulates the chemosensitivity of FaDu cells to taxol. Therefore, Twist1 knockdown may be a promising treatment regimen for advanced hypopharyngeal carcinoma patients with MDR.

  8. Berberine-induced anticancer activities in FaDu head and neck squamous cell carcinoma cells.

    PubMed

    Seo, Yo-Seob; Yim, Min-Ji; Kim, Bok-Hee; Kang, Kyung-Rok; Lee, Sook-Young; Oh, Ji-Su; You, Jae-Seek; Kim, Su-Gwan; Yu, Sang-Joun; Lee, Gyeong-Je; Kim, Do Kyung; Kim, Chun Sung; Kim, Jin-Soo; Kim, Jae-Sung

    2015-12-01

    In the present study, we investigated berberine‑induced apoptosis and the signaling pathways underlying its activity in FaDu head and neck squamous cell carcinoma cells. Berberine did not affect the viability of primary human normal oral keratinocytes. In contrast, the cytotoxicity of berberine was significantly increased in FaDu cells stimulated with berberine for 24 h. Furthermore, berberine increased nuclear condensation and apoptosis rates in FaDu cells than those in untreated control cells. Berberine also induced the upregulation of apoptotic ligands, such as FasL and TNF-related apoptosis-inducing ligand, and triggered the activation of caspase-8, -7 and -3, and poly(ADP ribose) polymerase, characteristic of death receptor-dependent extrinsic apoptosis. Moreover, berberine activated the mitochondria‑dependent apoptotic signaling pathway by upregulating pro-apoptotic factors, such as Bax, Bad, Apaf-1, and the active form of caspase-9, and downregulating anti-apoptotic factors, such as Bcl-2 and Bcl-xL. In addition, berberine increased the expression of the tumor suppressor p53 in FaDu cells. The pan-caspase inhibitor Z-VAD-fmk suppressed the activation of caspase-3 and prevented cytotoxicity in FaDu cells treated with berberine. Interestingly, berberine suppressed cell migration through downregulation of vascular endothelial growth factor (VEGF), matrix metalloproteinase (MMP)-2, and MMP-9. Moreover, the phosphorylation of extracellular signal-regulated kinase (ERK1/2) and p38, components of the mitogen-activated protein kinase pathway that are associated with the expression of MMP and VEGF, was suppressed in FaDu cells treated with berberine for 24 h. Therefore, these data suggested that berberine exerted anticancer effects in FaDu cells through induction of apoptosis and suppression of migration. Berberine may have potential applications as a chemotherapeutic agent for the management of head and neck squamous carcinoma.

  9. Antimicrobial activity of DU-6681a, a parent compound of novel oral carbapenem DZ-2640.

    PubMed Central

    Tanaka, M; Hohmura, M; Nishi, T; Sato, K; Hayakawa, I

    1997-01-01

    The in vitro antibacterial activity of DU-6681a, a parent compound of DZ-2640, against gram-positive and -negative bacteria was compared with those of penems and cephalosporins currently available. MICs at which 90% of the isolates are inhibited (MIC90s) of the compound for clinical isolates of methicillin-susceptible and -resistant Staphylococcus aureus and Staphylococcus epidermidis, including methicillin-susceptible and -resistant strains, were 0.10, 25, and 12.5 microg/ml, respectively. DU-6681a inhibited the growth of all strains of Streptococcus pyogenes and of penicillin-susceptible and -insusceptible Streptococcus pneumoniae at 0.006, 0.025, and 0.20 microg/ml, respectively, and MIC90s of the compound were 6.25 and >100 microg/ml for Enterococcus faecalis and Enterococcus faecium, respectively. MIC90s of DU-6681a were 0.20, 0.10, and 0.025 microg/ml for Haemophilus influenzae, Moraxella catarrhalis, and Neisseria gonorrhoeae, respectively. For Pseudomonas aeruginosa, the MIC50 and MIC90 of DU-6681a were 25 and 50 microg/ml, respectively. DU-6681a activity was not affected by different media, varied inoculum size (10(4) to 10(7) CFU), or the addition of human serum but was decreased under acidic conditions against gram-negative bacteria, under alkaline conditions against gram-positive bacteria, and in human urine, as was the activity of the other antibiotics tested. The frequency of spontaneous resistance to DU-6681a was less than or equal to those of the reference compounds. Time-kill curve studies demonstrated the bactericidal action of DU-6681a against S. aureus, S. pneumoniae, Escherichia coli, and H. influenzae. PMID:9174181

  10. Une tumeur rare et distincte du cancer du sein: le carcinosarcome, à propos de huit cas et revue de la littérature

    PubMed Central

    Ghanem, Samia; Khoyaali, Siham; Naciri, Sara; Glaoui, Meriem; Mesmoudi, Mohamed; Errihani, Hassan

    2013-01-01

    Le carcinosarcome du sein souvent appelé carcinome métaplasique du sein, est une tumeur maligne rare composée de deux lignées cellulaires distinctes, il est décrit comme un cancer du sein de type canalaire avec un composant de type sarcome. Il représente 0,08-0.2% de toutes les tumeurs malignes du sein. Il s'agit d'une étude rétrospective étalée sur un an, huit cas des carcinosarcomes mammaires ont été colligés à l'Institut national d'oncologie au Maroc durant l'année 2007. La médiane d’âge était de 49,5 ans, toutes les tumeurs étaient de haut grade, cliniquement 5 cas ont été classé t2 ou t3, et 3 cas classé sein localement avancé. Le traitement envisagé était basé sur une chirurgie mammaire suivie d'une radiothérapie et d'une chimiothérapie pour les cas adjuvants, l'envahissement ganglionnaire a été noté dans un cas, les récepteurs œstrogèniques sont négatifs, alors que les récepteurs progesteroniques sont positifs dans 4 cas, l'expression d'Her2 est absente dans tous les cas, le traitement des carcinosarcomes mammaires métastatiques était basé sur une chimiothérapie palliative. A 20 mois de médiane follow-up, la survie sans progression(SSP) pour le groupe entier est de 62,5%. Dans la limite de ce suivi, une rechute locorégionale a été détectée dans un cas, les deux patientes métastatiques sont décédées. Le carcinosarcome du sein est un sous-type rare du cancer du sein qui a un profil particulier et agressif, il a souvent un caractère triple négatif. Il est nécessaire de développer d'autres voies de recherche comme cibler le Récepteur HER1/EGFR. PMID:23734272

  11. When Cri du chat syndrome meets Edwards syndrome.

    PubMed

    Xie, Yingjun; Zhou, Yi; Wu, Jianzhu; Sun, Yunxia; Chen, Yongzhen; Chen, Baojiang

    2015-03-01

    It has been well established that the 5p deletion causes Cri du chat syndrome, typically characterized by a cat‑like cry, and that duplication of 18q causes Edwards syndrome; the two are rare genetic abnormalities that separately lead to physical and mental impairments. However, the severity of the clinicopathological characteristics that arise when these two aberrations occur in one patient is unknown. Here, the first case in our knowledge of a single patient (a two‑year‑old female) with 5p partial monosomy and 18q partial trisomy is described. In the present study, chromosome microarray analysis was performed, which identified the imbalance of chromosomes 5 and 18 in the patient. The chromosome aberrations were further confirmed by fluorescence in situ hybridization. By comparing the phenotypes of combined case with those of the individual syndromes, severe clinical phenotypes of the 5p (5p15.33‑p13.3) deletion were confirmed, however, the net effect of the duplication of 18q22.3‑q23 was not determined, as this duplication only appeared to have a weak effect on the patient's phenotypes. The correlation between these chromosomal aberrations and their clinical features has implications for the identification of critical regions of 5p and 18q, particularly for the functional mapping of chromosome 18. PMID:25385231

  12. Identification d'une loi thermo-élasto-viscoplastique en vue de la modélisation du laminage à chaud du cuivre

    NASA Astrophysics Data System (ADS)

    Moureaux, P.; Moto Mpong, S.; Remy, M.; Bouffioux, C.; Lecomte-Beckers, J.; Habraken, A. M.

    2002-12-01

    la mise au point d'un modèle de simulation de la dernière passe du laminage à chaud du cuivre ne présente à priori pas de problème du point de vue numérique pour un code d'éléments finis non linéaire. La collecte d'informations précises tant sur le procédé industriel que sur le comportement du matériau est par contre une opération non triviale. Cet article présente les diverses méthodes expérimentales mises en œuvre pour caractériser le matériau : essais de compression à chaud, mesures d'analyse thermique différentielle, essais de dilatométrie et de diffusivité. Les méthodes permettant d'identifier les paramètres de la loi élasto-visco-plastique de type Norton-Hoff à partir des essais sont présentées et une analyse bibliographique investigue le problème de la détermination du module de Young à haute température. Tant les hypothèses supplémentaires relatives au procédé et nécessaires au modèle que les résultats finaux sont résumés.

  13. Increase of human prostate cancer cell (DU145) apoptosis by telmisartan through PPAR-delta pathway.

    PubMed

    Wu, Tony Tong-Lin; Niu, Ho-Shan; Chen, Li-Jen; Cheng, Juei-Tang; Tong, Yat-Ching

    2016-03-15

    The effect of telmisartan on prostate cancer DU145 cell survival and the underlying mechanism of apoptosis involving peroxisome proliferator-activated receptor (PPAR) pathway were investigated. Cultured DU145 cells were treated pharmacologically with telmisartan and GSK0660 (a PPAR-delta antagonist); or by RNA interference with siRNA of PPAR-delta. The treatment effects on cell survival were evaluated with cell viability assay, life and dead cell staining and flow cytometry. Western blot analysis for PPAR-delta protein expression was also performed. The results showed that telmisartan (0-80 µm) dose-dependently reduced DU145 cell survival. Flow cytometry demonstrated cancer cell cycle arrest with increase of sub-G1 phase. GSK0660 partially but significantly restored the telmisartan-treated cell viability. Similarly, siRNA of PPAR-delta significantly reversed the telmisartan-induced apoptosis. Western blot showed that telmisartan significantly increased DU145 cell PPAR-delta protein expression. Co-incubation with siRNA of PPAR-delta inhibited the telmisartan effect of PPAR-delta up-regulation. In conclusion, telmisartan induces prostate cancer DU145 cells apoptosis through the up-regulation of PPAR-delta protein expression. Pharmacological inhibition or genetic silencing of PPAR-delta activity can both reverse the telmisartan-induced apoptotic effect. Thus the PPAR-delta pathway might be a potential target for the treatment of prostate cancer.

  14. Autre cause de mort subite du nourrisson: à propos d'un cas clinique de syndrome du QT long congenital

    PubMed Central

    Seka, Zena; Mols, Pierre; Gobin, Eric; Ngatchou, William

    2014-01-01

    Le syndrome du QT long congénital est une maladie rythmique liée à une mutation génétique et caractérisée par un espace QT allongé sur l’électrocardiogramme, des arythmies malignes type torsade de pointe et fibrillation ventriculaire entraînant une mort subite. Les gènes impliqués dans ces mutations codent pour des sous unités des canaux ioniques responsables de l'activité électrique cardiaque. Le diagnostic est basé sur l’électrocardiogramme, une enquête familiale et l’étude génétique. Le traitement repose sur les bêtabloquants, la sympathectomie et le stimulateur cardiaque. Nous rapportons le cas d'un nourrisson de 2 ans retrouvé en état de mort apparente. Nous discutons de sa prise en charge initiale, de l'enquête familiale et de son suivi ultérieur. PMID:25667708

  15. Cancer du sein bilatéral synchrone au Maroc: caractéristiques épidémiologiques et cliniques

    PubMed Central

    Boufettal, Houssine; Samouh, Naïma

    2015-01-01

    Préciser la fréquence, les facteurs de risque et le pronostic du cancer du sein bilatéral, à partir d'une étude rétrospective de 22 cas de cancer du sein bilatéral synchrone dans un pays du Maghreb. De 2002 à 2010, 625 patientes étaient prises en charge pour cancer du sein au service de Gynécologie-Obstétrique «C» du centre hospitalier universitaire de Casablanca. 22 cas de cancer bilatéral synchrone étaient diagnostiqués. Nos résultats sont comparés avec ceux de la littérature. La fréquence de la bilatéralité du cancer du sein synchrone était de 3,52% (22/625). L'intervalle de temps moyen entre les deux cancers est de 4 mois (0 à 6 mois). Les patientes âgées de moins de 40 ans lors du premier cancer avaient six fois plus de risque de développer un cancer au niveau du sein controlatéral que les femmes âgées de plus de 40 ans. Les patientes atteintes d'une tumeur T3 ou T4 avaient un risque neuf fois plus élevé que les autres. 90,9% (2/22) des cas des premiers cancers sont des adénocarcinomes infiltrants. Les types histologiques du premier et du douzième cancer étaient identiques dans 86,4% (19/22) des cas. Quant au pronostic, il dépend à la fois du stade du premier et du deuxième cancer et le traitement de ce dernier doit obéir aux mêmes règles du traitement du premier cancer. L'incidence du cancer bilatéral synchrone du sein est de 3,52% dans notre série. Le cancer du sein unilatéral constitue un facteur de risque de développement d'un cancer du sein controlatéral. Une surveillance à vie est nécessaire au cours d'un cancer du sein pour détecter un cancer controlatéral. PMID:26090066

  16. A Description of Adaptive and Maladaptive Behaviour in Children and Adolescents with Cri-du-Chat Syndrome

    ERIC Educational Resources Information Center

    Teixeira, M. C. T. V.; Emerich, D. R.; Orsati, F. T.; Rimerio, R. C.; Gatto, K. R.; Chappaz, I. O.; Kim, C. A.

    2011-01-01

    Background: Psychological tests can be useful to record adaptive and maladaptive behaviours of children with intellectual disability. The objective of this study was to describe the adaptive and maladaptive behaviour of children and adolescents with Cri-du-chat syndrome. Methods: The sample consisted of 10 children and adolescents with Cri-du-chat…

  17. Transportation Technology: Rail Transport and Logistics

    ERIC Educational Resources Information Center

    Lang, Aaron B.

    2011-01-01

    Transportation can simply be defined as the movement of goods, services, and people from one location to another. Without an efficient means to transport goods from place to place, the economy would be nothing like it is today. Throughout the history of the United States, American railroads have paved the way toward creating a nation of great…

  18. La genèse du concept de champ quantique

    NASA Astrophysics Data System (ADS)

    Darrigol, O.

    This is a historical study of the roots of a concept which has proved to be essential in modern particle physics : the concept of quantum field. The first steps were accomplished by two young theoreticians : Pascual Jordan quantized the free electromagnetic field in 1925 by means of the formal rules of the just discovered matrix mechanics, and Paul Dirac quantized the whole system charges + field in 1927. Using Dirac's equation for electrons (1928) and Jordan's idea of quantized matter waves (second quantization), Werner Heisenberg and Wolfgang Pauli provided in 1929-1930 an extension of Dirac's radiation theory and the proof of its relativistic invariance. Meanwhile Enrico Fermi discovered independently a more elegant and pedagogical formulation. To appreciate the degree of historical necessity of the quantization of fields, and the value of contemporaneous critics to this approach, it was necessary to investigate some of the history of the old radiation theory. We present the various arguments however provisional or naïve or wrong they could be in retrospect. So we hope to contribute to a more vivid picture of notions which, once deprived of their historical setting, might seem abstruse to the modern user. Nous présentons une étude historique des origines d'un concept devenu essentiel dans la physique moderne des particules : le concept de champ quantique. Deux jeunes théoriciens franchirent les premières étapes : Pascual Jordan quantifia le champ électromagnétique en 1925 grâce aux règles formelles de la mécanique des matrices naissante, et Paul Dirac quantifia le système complet charges + champ en 1927. Au moyen de l'équation de l'électron de Dirac (1928) et de l'idée de Jordan d'ondes de matière quantifiées (deuxième quantification), Werner Heisenberg et Wolfgang Pauli donnèrent en 1929-1930 une extension de la théorie du rayonnement de Dirac et la preuve de son invariance relativiste. Pendant ce temps Enrico Fermi découvrit ind

  19. Contribution de l'altimetrie satellitaire a l'etude de la variabilite du niveau d'eau du Delta interieur du fleuve Niger

    NASA Astrophysics Data System (ADS)

    Telly Diepkile, Adama

    measurements were then corrected to bring them in the same altimetry reference level as Topex/Poseidon, thereby producing time series of 17 years (1992-2009). Following this analysis, we proposed a waveform retracking algorithm that integrates the backscattering coefficient to the time scale of penetration of the radar pulse in a medium with a presence of vegetation. The idea here is to consider the heterogeneity of a medium such as the Delta, which can be covered with vegetation. For this, we introduce into the equation of the waveform, the backscattering coefficient estimated from the so called water cloud model, to create a new algorithm called retracking algorithm of water cloud. This algorithm was applied to the Envisat and OSTM/Jason-2 data. The results of the algorithm were validated with in situ measurements of the Direction Nationale de l'Hydraulique du Mali and also with measurements acquired during a campaign of data collection conducted between August and October 2009. The observed differences are generally small (<+/- 1 m). The retracking algorithm of water cloud was compared to other existing algorithms. It shows a strong correlation with Ice-1 (R 2 = 0,84). Finally, we analyzed the influence of precipitation on the variations of the altimetry-derived water levels. Three sources of precipitations from satellite measurements and reanalysis data were considered in three catchments (basin Fouta Djallon in upstream, Bani basin and the inner basin in Mali). The analysis reveals the importance of precipitations, particularly in the basin of Fouta Djallon. Approximately 70% of sites analyzed in the Delta show a relatively strong correlation (R2 > 0,40) with the cumulative precipitations in the basins considered. Keywords : Remote Sensing, Satellite altimetry, Continental waters, Water level, Long term analysis, Inner Delta of Niger River, Water-cloud model, Envisat, Topex/Poseidon.

  20. Coronagraphy at Pic du Midi: Present state and future projects

    NASA Astrophysics Data System (ADS)

    Koechlin, L.

    2012-12-01

    The Pic du Midi coronagraph (CLIMSO) is a group of four instruments in parallel, taking images of the whole solar photosphere and low corona. It provides series of 2048*2048 pixels images taken nominally at 1 minute time intervals, all year long, weather permitting. A team of ≃q 60 persons, by groups of 2 or 3 each week, operate the instruments. Their work is programmed in collaboration with Institut de Recherches en astrophysique et planétologie (IRAP) of Observatoire Midi Pyrénées (OMP), and with Programme National Soleil Terre (PNST). The four instruments of CLIMSO (L1, C1, L2 and C2) collect images of the Sun as following: 1) L1 : photosphere in H-α (656.28 nm) ; 2) L2 : photosphere in Ca-II (393.37 nm) ; 3) C1 : prominences in H-α ; 4) C2 : prominences in He-I (1083.0 nm). The data taken are stored in fits format images and mpeg films. They are available publicly on data bases such as BASS 2000 Meudon ({http://bass2000.obspm.fr/home.php?lang=en} and BASS2000 Tarbes ({http://bass2000.bagn.obs-mip.fr/base/sun/index.php}). Several solar studies are carried in relation with these data. In addition to the raw fits images, new images will soon be sent to the data bases: they will be calibrated in solar surface emittance, expressed in W/m^2/nm/steradian. Series of mpeg films for each day are presented in superposed color layers, so as to visualize the multispectral information better. New instrumental developments are planned for the next years and already financed. They will use spectropolarimetry to measure the magnetic field and radial velocities in the photosphere and corona. The data will cover the entire solar disc and have a sample rate of one map per minute.

  1. Purification, identification and preliminary crystallographic studies of Pru du amandin, an allergenic protein from Prunus dulcis

    SciTech Connect

    Gaur, Vineet; Sethi, Dhruv K.; Salunke, Dinakar M.

    2008-01-01

    The purification, identification, crystallization and preliminary crystallographic studies of an allergy-related protein, Pru du amandin, from P. dulcis nuts are reported. Food allergies appear to be one of the foremost causes of hypersensitivity reactions. Nut allergies account for most food allergies and are often permanent. The 360 kDa hexameric protein Pru du amandin, a known allergen, was purified from almonds (Prunus dulcis) by ammonium sulfate fractionation and ion-exchange chromatography. The protein was identified by a BLAST homology search against the nonredundant sequence database. Pru du amandin belongs to the 11S legumin family of seed storage proteins characterized by the presence of a cupin motif. Crystals were obtained by the hanging-drop vapour-diffusion method. The crystals belong to space group P4{sub 1} (or P4{sub 3}), with unit-cell parameters a = b = 150.7, c = 164.9 Å.

  2. Expression, purification, and characterization of almond (Prunus dulcis) allergen Pru du 4.

    PubMed

    Zhang, Yuzhu; Du, Wen-Xian; Fregevu, Cécile; Kothary, Mahendra H; Harden, Leslie; McHugh, Tara H

    2014-12-31

    Biochemical characterizations of food allergens are required for understanding the allergenicity of food allergens. Such studies require a relatively large amount of highly purified allergens. The level of Pru du 4 in almond is low, and its expression in a soluble form in Escherichia coli required an expression tag. An MBP tag was used to enhance its expression and solubility. Sumo was used for the first time as a peptidase recognition site. The expression tag was removed with a sumo protease, and the resulting wild-type Pru du 4 was purified chromatographically. The stability of the allergen was investigated with chemical denaturation. The Gibbs free energy of Pru du 4 folding-unfolding transition was determined to be 5.4 ± 0.7 kcal/mol.

  3. Secure Transportation Management

    SciTech Connect

    Gibbs, P. W.

    2014-10-15

    Secure Transport Management Course (STMC) course provides managers with information related to procedures and equipment used to successfully transport special nuclear material. This workshop outlines these procedures and reinforces the information presented with the aid of numerous practical examples. The course focuses on understanding the regulatory framework for secure transportation of special nuclear materials, identifying the insider and outsider threat(s) to secure transportation, organization of a secure transportation unit, management and supervision of secure transportation units, equipment and facilities required, training and qualification needed.

  4. Evaluation du niveau de connaissance des patients sur la gestion du traitement par les antis vitamines K dans le service de cardiologie de Ouagadougou

    PubMed Central

    Samadoulougou, André; Temoua Naibe, Dangwé; Mandi, Germain; Yameogo, Relwendé Aristide; Kabore, Elisé; Millogo, Georges; Yameogo, Nobila Valentin; Kologo, Jonas Koudougou; Thiam/Tall, Anna; Toguyeni, Boubacar Jean Yves; Zabsonre, Patrice

    2014-01-01

    Introduction Les antivitamines K (AVK), traitement anticoagulant oral le plus largement prescrit, posent un réel problème de santé publique du fait de leur risque iatrogène. L'objectif de cette étude était de préciser le niveau de connaissance des patients sur la gestion de leur traitement par les AVK. Méthodes Il s'est agi d'une enquête transversale descriptive réalisée au CHU-Yalgado Ouédraogo, sur une période de 03 mois : du 1er mars au 31 mai 2012. Un questionnaire a été administré aux patients bénéficiant d'un traitement AVK depuis au moins un mois. Résultats Soixante-dix patients ont été inclus dans l'étude dont 30 hommes. L'âge moyen était de 49 ans ± 16 ans. Les cardiopathies et la maladie thromboembolique veineuse justifiant l'institution du traitement AVK étaient retrouvées respectivement dans 58,6% et 41,4% des cas. Le nom de l'AVK et la raison exacte du traitement étaient connus respectivement dans 91,4% et 67,1% des cas. Plus de la moitié des patients (68,6%) savaient que les AVK rendaient le sang plus fluide. Quarante-six patients (65,7%) citaient l'INR comme examen biologique de surveillance du traitement et seulement 28 patients (40%) connaissaient les valeurs cibles. La majorité des patients ne connaissait pas les risques encourus en cas de surdosage (72,8%) et de sous-dosage (71,4%). Une automédication par anti-inflammatoire non stéroïdien était signalée par 18 patients (25,7%). Les choux (74,3%) et la laitue (62,9%), aliments à consommer avec modération, étaient les plus cités. Conclusion Les connaissances des patients sur la gestion des AVK étaient fragmentaires et insuffisantes pour assurer la sécurité et l'efficacité du traitement. La création d'un programme d'éducation thérapeutique sur les AVK s'avère alors nécessaire. PMID:25870741

  5. In vitro and in vivo antimycobacterial activities of a new quinolone, DU-6859a.

    PubMed

    Saito, H; Tomioka, H; Sato, K; Dekio, S

    1994-12-01

    A new fluoroquinolone, DU-6859a, was studied for its in vitro and in vivo antimycobacterial activities. MIC determination by the agar dilution method with 7H11 medium revealed that DU-6859a had MICs at which 90% of M. kansasii (0.78 microgram/ml), M. marinum (1.56 micrograms/ml), M. scrofulaceum (1.56 micrograms/ml), M. fortuitum (0.39 microgram/ml), M. chelonae subsp. abscessus (6.25 micrograms/ml), and M. chelonae subsp. chelonae (1.56 micrograms/ml) were inhibited were 4 to 32 times lower than those of ofloxacin and sparfloxacin. The MICs of DU-6859a at which 90% of M. tuberculosis (0.2 microgram/ml) and M. avium-M. intracellulare complex (12.5 micrograms/ml each) were inhibited were comparable to those of sparfloxacin but were four- to eightfold lower than those of ofloxacin. Thus, DU-6859a possessed more potent in vitro activity than sparfloxacin and ofloxacin against most mycobacterial species. DU-6859a exerted significant efficacy against infections caused by M. intracellulare and M. chelonae subsp. abscessus induced in mice when it was given at a dose of 1 mg per mouse (ca. 50 mg/kg of body weight) in terms of reducing the frequency of occurrence and the degree of gross pulmonary or renal lesions and bacterial loads in the lungs, spleens, or kidneys. The efficacy of DU-6859a was greater than that of ofloxacin and was more pronounced against M. chelonae infections than against M. intracellulare infections. PMID:7695276

  6. Dépistage précoce des retards du développement moteur

    PubMed Central

    Harris, Susan R.

    2016-01-01

    Résumé Objectif Décrire le test HINT (Harris Infant Neuromotor Test), un test d’évaluation du développement neuromoteur chez les nourrissons publié en 2010, qui s’appuie sur les normes canadiennes et peut être utilisé pour dépister les retards du développement moteur durant la première année de la vie. Qualité des données D’abondantes recherches ont été publiées sur la fiabilité intra-évaluateur, inter-évaluateur et test-retest ainsi que sur la validité convergente, prédictive, du contenu et des groupes connus du test HINT, de même que sur la sensibilité, la spécificité et les valeurs prédictives négatives et positives des inquiétudes des parents, telles qu’évaluées par le test HINT. La plupart des données probantes sont de niveau II. Message principal Il est important de diagnostiquer les retards du développement moteur durant la première année de vie, car ils sont souvent le signe de retards du développement généralisés ou de déficiences précises, telles que la paralysie cérébrale. Les inquiétudes des parents quant au développement moteur de leur enfant sont une valeur prédictive robuste de diagnostics subséquents de retard du développement moteur. Conclusion Seul le dépistage précoce des retards du développement moteur, initialement par l’entremise d’outils de dépistage comme le test HINT, permet de recommander le patient à une intervention précoce qui profiterait tant à l’enfant qu’à sa famille. PMID:27521405

  7. Intubation Difficile Chez le Brule de la Face et du Cou a la Phase de Sequelles

    PubMed Central

    Siah, S.; El Wali, A.; Ababou, K.; Nassim Sabah, T.; Drissi, N.K.; Ihrai, I.

    2006-01-01

    Summary L'intubation trachéale chez le brûlé de la face et du cou au stade de séquelles peut être difficile voire impossible chez certains patients. La technique de ventilation à l'aide d'un masque laryngé ou d'intubation avec un fibroscope bronchique permet de résoudre la plupart des problèmes d'intubation difficile. Les Auteurs rapportent deux observations chez deux patientes porteuses de séquelles de brûlures de la face et du cou. PMID:21991028

  8. Strangulation du colon sigmoïdien par un testicule ectopique géant

    PubMed Central

    Sanogo, Zimogo; Koita, Adama; Camara, Moussa; Soumaré, Lamine; Kamaté, Bakarou; Doumbia, Dieneba; Ouattara, Zanafon; Tembely, Ali; Yena, Sadio; Coulibaly, Youssouf; Sangaré, Djibril

    2012-01-01

    Les causes de volvulus du colon sigmoïde sont variées et parmi elles la strangulation est des plus fréquentes dans notre contexte d’exercice. Les lésions vues tard permettent très rarement un traitement sans résection. La survenue d’un volvulus du colon sigmoïde autour d’un pédicule de testicule géant ectopique est une première que nous rapportons dans cette étude de cas. PMID:22593796

  9. Docetaxel induces Bcl-2- and pro-apoptotic caspase-independent death of human prostate cancer DU145 cells

    PubMed Central

    OGURA, TAKEHARU; TANAKA, YOSHIYUKI; TAMAKI, HIROKI; HARADA, MAMORU

    2016-01-01

    Docetaxel is a useful chemotherapeutic agent for the first-line treatment of hormone-refractory prostate cancer. Abnormal expression of Bcl-2 is commonly found in cancer cells, which increases their anti-apoptotic potency and chemo-resistance. We investigated the effects of Bcl-2 expression status on the susceptibility of DU145 cells, an androgen-independent human prostate cancer cell line, to docetaxel and other anticancer agents. A panel of Bcl-2-expressing DU145 cell lines was established. Bcl-2 expression levels were unrelated to the susceptibility of DU145 cells to docetaxel. The sensitivity of DU145 cells to cisplatin fluctuated, and the sensitivity to tumor necrosis factor (TNF)-α was decreased by Bcl-2 overexpression. In a xenograft mouse model, overexpression of Bcl-2 drastically decreased the sensitivity of DU145 cells to cisplatin and TNF-α; however, there was no change in the response to docetaxel. Fluorescent microscopy revealed that Bcl-2-overexpression had no effect on the docetaxel-induced death of DU145 cells, but significantly decreased DU145 cell death induced by cisplatin or TNF-α. Interestingly, docetaxel hardly induced caspase-3/7 activation in control or Bcl-2-overexpressing DU145 cells, but did at a low level in LNCaP cells, another prostate cancer cell line. Moreover, in contrast to LNCaP cells, the reduced viabilities of docetaxel-treated control and Bcl-2-overexpressing DU145 cells were not restored by the addition of either a Bid inhibitor or a panel of pro-apoptotic caspase inhibitors. These findings indicate that the antitumor effects of docetaxel on DU145 cells are independent of both Bcl-2 and pro-apoptotic caspases. PMID:27082738

  10. Transportation Management Workshop: Proceedings

    SciTech Connect

    Not Available

    1993-10-01

    This report is a compilation of discussions presented at the Transportation Management Workshop held in Gaithersburg, Maryland. Topics include waste packaging, personnel training, robotics, transportation routing, certification, containers, and waste classification.

  11. Transportation and handling loads

    NASA Technical Reports Server (NTRS)

    Ostrem, F. E.

    1971-01-01

    Criteria and recommended practices are presented for the prediction and verification of transportation and handling loads for the space vehicle structure and for monitoring these loads during transportation and handling of the vehicle or major vehicle segments. Elements of the transportation and handling systems, and the forcing functions and associated loads are described. The forcing functions for common carriers and typical handling devices are assessed, and emphasis is given to the assessment of loads at the points where the space vehicle is supported during transportation and handling. Factors which must be considered when predicting the loads include the transportation and handling medium; type of handling fixture; transport vehicle speed; types of terrain; weather (changes in pressure of temperature, wind, etc.); and dynamics of the transportation modes or handling devices (acceleration, deceleration, and rotations of the transporter or handling device).

  12. Thermodynamics of nuclear transport

    NASA Astrophysics Data System (ADS)

    Wang, Ching-Hao; Mehta, Pankaj; Elbaum, Michael

    Molecular transport across the nuclear envelope is important for eukaryotes for gene expression and signaling. Experimental studies have revealed that nuclear transport is inherently a nonequilibrium process and actively consumes energy. In this work we present a thermodynamics theory of nuclear transport for a major class of nuclear transporters that are mediated by the small GTPase Ran. We identify the molecular elements responsible for powering nuclear transport, which we term the ``Ran battery'' and find that the efficiency of transport, measured by the cargo nuclear localization ratio, is limited by competition between cargo molecules and RanGTP to bind transport receptors, as well as the amount of NTF2 (i.e. RanGDP carrier) available to circulate the energy flow. This picture complements our current understanding of nuclear transport by providing a comprehensive thermodynamics framework to decipher the underlying biochemical machinery. Pm and CHW were supported by a Simons Investigator in the Mathematical Modeling in Living Systems grant (to PM).

  13. Mixing and Transport.

    PubMed

    Chang, Chein-Chi; Chapman, Tom; Siverts-Wong, Elena; Wei, Li; Mei, Ying

    2016-10-01

    This section covers research published during the calendar year 2015 on mixing and transport processes. The review covers mixing of anaerobic digesters, mixing of heat transfer, and environmental fate and transport. PMID:27620101

  14. Basic Transportation Economics

    NASA Technical Reports Server (NTRS)

    Kneafsey, J. T.

    1972-01-01

    Transportation economics is an integral part of all transportation activities. Refined, detailed, and careful economic analyses consider conduct-performance methodology and the specifications of production, cost and demand functions.

  15. Transport aérien longue distance des brûlés graves: revue de la littérature et application pratique

    PubMed Central

    Leclerc, T.; Hoffmann, C.; Forsans, E.; Cirodde, A.; Boutonnet, M.; Jault, P.; Tourtier, J.-P.; Bargues, L.; Donat, N.

    2015-01-01

    Summary Les brûlés graves nécessitent une prise en charge multidisciplinaire dans des centres hautement spécialisés. La rareté de ces centres impose souvent le transport aérien médicalisé longue distance. Cependant, il y a peu de données publiées sur ces transferts. Dans cette mise au point, pour optimiser la prise en charge des brûlés dès qu’un transport aérien est décidé ou même seulement envisagé, nous proposons d’extraire de cette littérature limitée des principes simples s’appuyant aussi sur l’expérience pratique du Service de Santé des Armées françaises. Nous décrivons d’abord comment les contraintes aéronautiques peuvent affecter le transport de brûlés graves à bord d’aéronefs. Nous abordons ensuite la régulation de ces missions, en analysant les risques associés au transport aérien des brûlés graves et leurs implications sur les indications, la chronologie et les modalités du transport. Enfin, nous développons la conduite de la mission, comprenant la préparation du matériel et des consommables avant le vol, l’évaluation et la mise en condition du patient avant l’embarquement, et la poursuite de la prise en charge en vol. PMID:26668564

  16. Subseabed disposal transportation system

    SciTech Connect

    Allen, Jr., G. C.; Vernon, M. E.; Anderson, D. R.

    1980-01-01

    Transportation requirements and interfaces are being considered in the evaluation of the seabed disposal option. Technical direction and planning are on-going to ensure the development of major transportation systems in support of the seabed disposal option. Factors which affect the risk and effectiveness of transportation are being included in site selection criteria. However, detailed development of port facilities and transport/emplacement equipment is still several years into the future. (DMC)

  17. Étude de la condensation par convection forcée du R113, R152a et du R12 sur une plaque plane horizontale

    NASA Astrophysics Data System (ADS)

    Louahlia, H.; Panday, P. K.

    1996-07-01

    Forced convection condensation of pure vapour flowing between two horizontal parallel plates with the bottom plate cooled is analysed numerically. The coupled boundary layer equations for the two phases are solved using an implicite finite difference procedure. The pressure gradient, shear stress, inertia and enthalpy convection terms, and turbulence in the two phases are retained in this analysis. The laminar model and the turbulent models of Pletcher [19] and Koyama et al. [20] are compared for condensation of R113. The mean heat transfer coefficients predicted with the model of Pletcher [19] are in good agreement with the experimental results of Lu and Suryanarayana [18]. The thermal performances of R152a and R12 are also compared. For the condensation of R152a, the pressure drop is 18% smaller and the mean heat transfer coefficients are 24% higher compared to those of R12. These results are in line with the experimental work of Cheng and Tao [12]. The influence of the temperature difference and inclination of the plate on the condensate film thikness are also reported. The results of the present calculations for the condensation of R12, R152a and R113 are represented by a non-dimensional equation. La condensation en film par convection forcée est analysé numériquement pour un écoulement de vapeur pure saturée entre deux plaques planes horizontales. Le condensat se forme uniquement sur une plaque inférieure. Les équations de la couche limite appliquées dans les deux phases sont couplées et résolues par une méthode des différences finies implicite. Le gradient de pression, les contraintes tangentielles, les termes d'inertie et de convection d'enthalpie ainsi que la turbulence dans les deux phases sont pris en compte. Le modèle laminaire ainsi que les modèles de turbulence de Pletcher [19] et de Koyama et al. [20] sont comparés pour la condensation du R113. Les coefficients d'échange thermique moyens prédits avec le modèle de Pletcher, s

  18. Cabrillo College Transportation Study.

    ERIC Educational Resources Information Center

    Willett, Terrence

    This report provides results of the survey and other sources of information which have been used to develop a transportation management plan at Cabrillo College (California). In 2000, Cabrillo College organized a Transportation Management Committee to review the existing transportation situation and develop and implement a plan with the goal of…

  19. Transportation in African Development.

    ERIC Educational Resources Information Center

    Altschul, Robert D.

    1980-01-01

    Examines the structure, role, and needs of Africa's national and intracontinental transportation system. Characteristics of rail, water, road, and air transportation are examined. The conclusion is that high investment in transportation systems is essential to the development process. (Author/KC)

  20. Ossification post-traumatique du ligament collatéral médial du genou: à propos d’un cas

    PubMed Central

    Arabi, Hafid; Sellahi, Hicham

    2016-01-01

    L’ossification hétérotopique est une ossification pathologique des parties molles. C’est une affection bénigne, récidivante et de survenue imprévisible. On décrit le cas d’un patient, traité pour une fracture du plateau tibial gauche avec mise en place d’une plaque vissée. A deux mois de l’opération, le patient a présenté une raideur du genou gauche. Le bilan radiologique standard a révélé une ossification du ligament latéral interne (LLI), confirmée par la tomodensitométrie. On ne sait pas actuellement les facteurs déterminant l’ossification des ligaments et tendons. Bien que les cliniciens prescrivent souvent des médicaments prophylactiques tels que les anti-inflammatoires et des séances de radiothérapie pour prévenir l’ossification hétérotopique des parties molles; la physiopathologie de l’ossification hétérotopique est peu connue. PMID:27800107

  1. Rapport sur l'état du patrimoine astronomique dans les observatoires français de la fin du XIXè siècle

    NASA Astrophysics Data System (ADS)

    Damm, E.; Pécontal, E.

    2012-12-01

    Suite au colloque sur la sauvegarde du patrimoine astronomique organisé par le MAEE et la SAF, sous l'égide de l'UNESCO, qui a conduit à l'adoption de la Déclaration de Paris, les directeurs d'observatoires institutionnels qui étaient absents du colloque ont ressenti le besoin de discuter de ces conclusions prises en leur nom. L'initiative d'organiser une réunion des directeurs des Observatoires des Sciences de l'Univers (OSU) à ce sujet le 30 janvier 2012 a été prise par François Vernotte, directeur de l'Observatoire de Besançon. Le présent compte-rendu de visite résulte d'une initiative spontanée d'Emmanuel Pécontal, astronome responsable du Patrimoine à l'observatoire de Lyon, et d'Evelyne Damm, membre de la Commission Nationale de classement des Monuments Historiques (CNMH) et élue à la communauté d'agglomération des Portes de l'Essonne oû est sis l'observatoire de Camille Flammarion.

  2. Aspects épidémiologiques du suicide à Dakar

    PubMed Central

    Soumah, Mohamed Maniboliot; Eboué, Brice Angwé; Ndiaye, Mor; Sow, Mamadou Lamine

    2013-01-01

    Introduction Le suicidé est le sujet mort par suicide et le suicidant est la personne ayant fait des tentatives de suicide. L'objectif de cette étude porte sur l'analyse épidémiologique des suicides dans la région de Dakar. Méthodes Par une étude rétrospective portant sur les registres du service d'anatomie pathologique de l'Hôpital Aristide Le Dantec, nous rapportons 143 suicides sur 10 ans. Le traitement et l'analyse des données ont été faits sur Epidata version 2.1 b pour la saisie et Epiinfo version 6.04 fr pour l'analyse. Résultats A Dakar, les morts par suicide restent peu fréquentes au regard de la mortalité générale. Les hommes se suicident deux fois plus que les femmes et le suicide reste l'apanage de l'adulte jeune dont l'âge se situe entre 21 et 30 ans. Les suicidés résident le plus souvent en zone périurbaine et ils commettent cet acte dans la majorité des cas en période de froid (pendant les mois de janvier, février et mars), plus avant midi et en soirée qu'en après-midi. Aussi 97.2% des suicidés ont utilisé un seul moyen pour se suicider et le suicide complexe (utilisation de plusieurs moyens) a concerné seulement un cas dans notre étude. La pendaison reste le mode le plus utilisé. Conclusion Les hommes préfèrent donc des moyens de suicides violents (pendaison, arme à feu et arme blanche) alors que les femmes et les adolescents (tout sexe confondu) utilisent les intoxications. Le recueil des facteurs concourant au suicide permettrait une prévention de ce dernier. PMID:23847707

  3. Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition.

    PubMed

    Mikkaichi, Tsuyoshi; Yoshigae, Yasushi; Masumoto, Hiroshi; Imaoka, Tomoki; Rozehnal, Veronika; Fischer, Thomas; Okudaira, Noriko; Izumi, Takashi

    2014-04-01

    Edoxaban (the free base of DU-176b), an oral direct factor Xa inhibitor, is mainly excreted unchanged into urine and feces. Because active membrane transport processes such as active renal secretion, biliary excretion, and/or intestinal secretion, and the incomplete absorption of edoxaban after oral administration have been observed, the involvement of drug transporters in the disposition of edoxaban was investigated. Using a bidirectional transport assay in human colon adenocarcinoma Caco-2 cell monolayers, we observed the vectorial transport of [(14)C]edoxaban, which was completely inhibited by verapamil, a strong P-glycoprotein (P-gp) inhibitor. In an in vivo study, an increased distribution of edoxaban to the brain was observed in Mdr1a/1b knockout mice when compared with wild-type mice, indicating that edoxaban is a substrate for P-gp. However, there have been no observations of significant transport of edoxaban by renal or hepatic uptake transporters, organic anion transporter (OAT)1, OAT3, organic cation transporter (OCT)2, or organic anion transporting polypeptide (OATP)1B1. Edoxaban exhibited no remarkable inhibition of OAT1, OAT3, OCT1, OCT2, OATP1B1, OATP1B3, or P-gp up to 30 μM; therefore, the risk of clinical drug-drug interactions due to any edoxaban-related transporter inhibition seems to be negligible. Our results demonstrate that edoxaban is a substrate of P-gp but not of other major uptake transporters tested. Because metabolism is a minor contributor to the total clearance of edoxaban and strong P-gp inhibitors clearly impact edoxaban transport, the P-gp transport system is a key factor for edoxaban's disposition.

  4. Theory of contributon transport

    SciTech Connect

    Painter, J.W.; Gerstl, S.A.W.; Pomraning, G.C.

    1980-10-01

    A general discussion of the physics of contributon transport is presented. To facilitate this discussion, a Boltzmann-like transport equation for contributons is obtained, and special contributon cross sections are defined. However, the main goal of this study is to identify contributon transport equations and investigate possible deterministic solution techniques. Four approaches to the deterministic solution of the contributon transport problem are investigated. These approaches are an attempt to exploit certain attractive properties of the contributon flux, psi = phi phi/sup +/, where phi and phi/sup +/ are the solutions to the forward and adjoint Boltzmann transport equations.

  5. Pharmacology of Iron Transport

    PubMed Central

    Byrne, Shaina L.; Krishnamurthy, Divya; Wessling-Resnick, Marianne

    2013-01-01

    Elucidating the molecular basis for the regulation of iron uptake, storage, and distribution is necessary to understand iron homeostasis. Pharmacological tools are emerging to identify and distinguish among different iron transport pathways. Stimulatory or inhibitory small molecules with effects on iron uptake can help characterize the mechanistic elements of iron transport and the roles of the transporters involved in these processes. In particular, iron chelators can serve as potential pharmacological tools to alleviate diseases of iron overload. This review focuses on the pharmacology of iron transport, introducing iron transport membrane proteins and known inhibitors. PMID:23020294

  6. Transportation Business Plan

    SciTech Connect

    Not Available

    1986-01-01

    The Transportation Business Plan is a step in the process of procuring the transportation system. It sets the context for business strategy decisions by providing pertinent background information, describing the legislation and policies governing transportation under the NWPA, and describing requirements of the transportation system. Included in the document are strategies for procuring shipping casks and transportation support services. In the spirit of the NWPA directive to utilize the private sector to the maximum extent possible, opportunities for business ventures are obvious throughout the system development cycle.

  7. Transportation safety training

    SciTech Connect

    Jones, E.

    1990-01-01

    Over the past 25 years extensive federal legislation involving the handling and transport of hazardous materials/waste has been passed that has resulted in numerous overlapping regulations administered and enforced by different federal agencies. The handling and transport of hazardous materials/waste involves a significant number of workers who are subject to a varying degree of risk should an accident occur during handling or transport. Effective transportation training can help workers address these risks and mitigate them, and at the same time enable ORNL to comply with the federal regulations concerning the transport of hazardous materials/waste. This presentation will outline how the Environmental and Health Protection Division's Technical Resources and Training Section at the Oak Ridge National Laboratory, working with transportation and waste disposal personnel, have developed and implemented a comprehensive transportation safety training program to meet the needs of our workers while satisfying appropriate federal regulations. 8 refs., 3 tabs.

  8. Urban public transport today

    SciTech Connect

    Simpson, B. )

    1994-01-01

    It is widely recognized that there are many people for whom public transport is essential, particularly among the elderly, children and teenagers. Less obvious is the dependence of our cities for their existence on high capacity public transport. Although there is still a prevalent view that local public transport is only for those who do not have a car, we are slowly beginning to realize that we need to find ways of restricting use of the private car more severely and that will involve some transfer to public transport. Urban Public Transport Today gives an honest appraisal of the pros and cons of new public transport technologies. It shows how public transport can be made a less unacceptable alternative to the private car than it is now.

  9. Transportation System Requirements Document

    SciTech Connect

    Not Available

    1993-09-01

    This Transportation System Requirements Document (Trans-SRD) describes the functions to be performed by and the technical requirements for the Transportation System to transport spent nuclear fuel (SNF) and high-level radioactive waste (HLW) from Purchaser and Producer sites to a Civilian Radioactive Waste Management System (CRWMS) site, and between CRWMS sites. The purpose of this document is to define the system-level requirements for Transportation consistent with the CRWMS Requirement Document (CRD). These requirements include design and operations requirements to the extent they impact on the development of the physical segments of Transportation. The document also presents an overall description of Transportation, its functions, its segments, and the requirements allocated to the segments and the system-level interfaces with Transportation. The interface identification and description are published in the CRWMS Interface Specification.

  10. Negotiating Legacies: Audre Lorde, W.E.B. Du Bois, Marlon Riggs, and Me.

    ERIC Educational Resources Information Center

    Price-Spratley, Townsand

    1996-01-01

    Demonstrates how the writing of Audre Lorde, W. E. B. Du Bois, and Marlon Riggs contributed to the author's personal and professional development as a homosexual scholar of African descent. Describes negotiating legacies as the process of understanding the contexts and contributions of cultural ancestors. (SK)

  11. Valeria Fike: College of DuPage Library, Glen Ellyn, IL

    ERIC Educational Resources Information Center

    Berry, John N., III

    2006-01-01

    In this article, the author profiles Valeria Fike, supervisor of reference support and College and Career Information Center services at the College of DuPage Library (CODL), Glen Ellyn, Illinois. Valeria Fike, who supervises some 21 paraprofessionals at CODL, modestly attributes her successful career there to her being "simply in the right place…

  12. Speech and Language Development in Cri Du Chat Syndrome: A Critical Review

    ERIC Educational Resources Information Center

    Kristoffersen, Kristian Emil

    2008-01-01

    This article reviews research on speech and language abilities in people with cri du chat syndrome (CCS). CCS is a rare genetic disorder, with an estimated incidence between 1 in 15,000 and 1 in 50,000 births, resulting from a deletion on the short arm of chromosome 5. In general, individuals have delayed speech and language development, and some…

  13. Sleep in Individuals with Cri du Chat Syndrome: A Comparative Study

    ERIC Educational Resources Information Center

    Maas, A. P. H. M.; Didden, R.; Korzilius, H.; Braam, W.; Smits, M. G.; Curfs, L. M. G.

    2009-01-01

    Background: Sleep problems are common in individuals with intellectual disability. Little is known about sleep in children and adults with Cri du Chat syndrome (CDC). Method: Sleep was investigated in 30 individuals with CDC using a sleep questionnaire. Sleep problems and sleep behaviours in individuals with CDC were compared with individuals with…

  14. 76 FR 78968 - Environmental Impact Statement: Cook and DuPage Counties, IL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-20

    ... Statement will be prepared for the Elgin O'Hare--West Bypass in Cook and DuPage Counties, Illinois. FOR... Statement (EIS) for the proposed Elgin O'Hare--West Bypass. The ISTHA is being added as a joint lead...

  15. Anthocyanin Induces Apoptosis of DU-145 Cells In Vitro and Inhibits Xenograft Growth of Prostate Cancer

    PubMed Central

    Ha, U-Syn; Bae, Woong Jin; Kim, Su Jin; Yoon, Byung Il; Hong, Sung Hoo; Lee, Ji Youl; Hwang, Tae-Kon; Hwang, Sung Yeoun; Wang, Zhiping

    2015-01-01

    Purpose To investigate the effects of anthocyanins extracted from black soybean, which have antioxidant activity, on apoptosis in vitro (in hormone refractory prostate cancer cells) and on tumor growth in vivo (in athymic nude mouse xenograft model). Materials and Methods The growth and viability of DU-145 cells treated with anthocyanins were assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and apoptosis was assessed by DNA laddering. Immunoblotting was conducted to evaluate differences in the expressions of p53, Bax, Bcl, androgen receptor (AR), and prostate specific antigen (PSA). To study the inhibitory effects of anthocyanins on tumor growth in vivo, DU-145 tumor xenografts were established in athymic nude mice. The anthocyanin group was treated with daily oral anthocyanin (8 mg/kg) for 14 weeks. After 2 weeks of treatment, DU-145 cells (2×106) were inoculated subcutaneously into the right flank to establish tumor xenografts. Tumor dimensions were measured twice a week using calipers and volumes were calculated. Results Anthocyanin treatment of DU-145 cells resulted in 1) significant increase in apoptosis in a dose-dependent manner, 2) significant decrease in p53 and Bcl-2 expressions (with increased Bax expression), and 3) significant decrease in PSA and AR expressions. In the xenograft model, anthocyanin treatment significantly inhibit tumor growth. Conclusion This study suggests that anthocyanins from black soybean inhibit the progression of prostate cancer in vitro and in a xenograft model. PMID:25510742

  16. Developing a Computer Literate Faculty at College of DuPage.

    ERIC Educational Resources Information Center

    Carlson, Bart

    Until 1978, academic and administrative departments at College of DuPage, an Illinois community college, bought computer related equipment and software without an overall plan or coordination. The development of a coordination plan focused on finding an internal mechanism to solve two problems: individual departments buying computer-related…

  17. DuPont extends CFC production after EPA warns of scarcity

    SciTech Connect

    Kirschner, E.

    1994-01-05

    DuPont reversed its voluntary commitment to phase out CFC production at the end of 1994 to prevent a possible shortage for automotive air conditioning repairs. In a December letter, the US EPA asked Dupont to continue producing its full 1995 allowance of 76 million tons of CFC-12 under the Montreal Protocol.

  18. The Double-Consciousness of Du Bois & the "Mestiza Consciousness" of Anzaldua.

    ERIC Educational Resources Information Center

    Martinez, Theresa A.

    2002-01-01

    Suggests that W.E.B. Du Bois' concept of the "double-consciousness" and Gloria Anzaldua's concept of the "mestiza consciousness" are significant forms of oppositional culture and consciousness. Asserts that their two concepts are linked and nuanced ideas that describe interlocking systems of oppression spanning two centuries and arguably binding…

  19. 77 FR 2774 - Notice of Intent To Prepare a Supplemental Environmental Impact Statement: Fond du Lac...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... Statement: Fond du Lac & Sheboygan Counties, WI AGENCY: Federal Highway Administration (FHWA), DOT. ACTION... Road, Suite 8000, Madison, WI 53717-2157; Telephone: (608) 662-2119. You may also contact Rebecca...., Madison, WI 53704-2549; Telephone (608) 246-5399. SUPPLEMENTARY INFORMATION: The FHWA, in cooperation...

  20. Perceptions of the Impacts of the "Arts du Cirque" Program: A Case Study

    ERIC Educational Resources Information Center

    Deslandes, Rollande; Rivard, Marie-Claude; Joyal, France; Trudeau, Francois

    2010-01-01

    This qualitative study used focus groups to identify the knowledge about the "Arts du Cirque" Program implemented in a primary school and to explore perceptions of its impacts. Data are based on the discourse of school staff members, parents and other members of the community of an elementary school. The impacts on students are illustrated in…

  1. KHAN DU! II. Final Project Performance Report, November 1, 1978-September 30, 1979.

    ERIC Educational Resources Information Center

    KLRN/KLRU-TV, Austin, TX.

    This KHAN DU! project produced four half-hour television programs in the area of career education with emphasis on the handicapped, plus an extra nonbroadcast program designed for teachers. The four-program series was designed for children aged eight to eleven, although older children have responded favorably. The goals of the series were (1) to…

  2. Conducting Approaches and Recommendations for the Performance of Igor Stravinsky's "L'Histoire du Soldat"

    ERIC Educational Resources Information Center

    Denti, Joseph R.

    2013-01-01

    This study examines "L'Histoire du Soldat" from the conductor's perspective. The review of literature examines texts on score study and conducting technique, analyzes writing on the interpretation of Stravinsky's conducting approach and his view on conductors, and provides works on the history and analysis of "L'Histoire du…

  3. Problem Behaviors Associated with Deletion Prader-Willi, Smith-Magenis, and Cri Du Chat Syndromes.

    ERIC Educational Resources Information Center

    Clarke, David J.; Boer, Harm

    1998-01-01

    Problem behaviors of 38 individuals with Cri-du-Chat syndrome, 55 individuals with Prader Willi syndrome, and 21 individuals with Smith-Magenis syndrome were investigated. All three disorders were Associated with greater ratings of problem behaviors (besides eating abnormalities and sleep abnormalities) than comparison groups. (Author/CR)

  4. Grammatical Constructions in Cri du Chat Syndrome--Findings from a Case Study

    ERIC Educational Resources Information Center

    Kristoffersen, Kristian Emil

    2009-01-01

    The literature on grammatical skills in persons with Cri du chat syndrome (CCS) is very limited, and the need for more knowledge in this area is thus evident, in particular for speech and language therapists working with individuals with this syndrome. This case study report describes the syntactic skills of a 14-year-old Norwegian girl with CCS.…

  5. Receptive and Expressive Language Skills in Children with Cri-du-Chat Syndrome.

    ERIC Educational Resources Information Center

    Cornish, K. M.; Munir, F.

    1998-01-01

    Receptive and expressive language skills were assessed in 13 British children (ages 4-14) with cri-du-chat syndrome. Results found a discrepancy between the children's chronological ages and their presumed language ages and a receptive-expressive discrepancy, with reduced expressive skills compared to receptive skills. Remediation that focuses on…

  6. Young Children with Cri-du-Chat: Genetic, Developmental, and Behavioral Profiles.

    ERIC Educational Resources Information Center

    Baird, Samera M.; Campbell, Dennis; Ingram, Rebecca; Gomez, Caroline

    2001-01-01

    This paper describes the developmental and behavioral patterns of 13 prelinguistic children (ages 11 to 47 months) with Cri-du-chat syndrome (CDCS). Parents provided demographic and genetic information, descriptions of their child's typical behavior, and completed a developmental checklist. Developmental, behavioral, and genetic profiles are…

  7. Inflectional Morphology in Cri du Chat Syndrome--A Case Study

    ERIC Educational Resources Information Center

    Kristoffersen, Kristian Emil

    2012-01-01

    This study examined morphological skills in a girl with cri du chat syndrome, addressing three questions: (1) To what extent does the subject inflect words? (2) To what extent are words inflected correctly? (3) To what extent do the inflected words reflect productive morphological rules, and to what extent can they be considered to be…

  8. Phonatory and Phonetic Characteristics of Prelinguistic Vocal Development in Cri Du Chat Syndrome.

    ERIC Educational Resources Information Center

    Sohner, Linda; Mitchell, Pamela

    1991-01-01

    Vocal samples were collected from a child with cri du chat syndrome from the age of 8 to 26 months. Analyses indicated that the high vocal fundamental was characteristic of comfort state vocalizations of the child. There was a predominance of falling intonation contours and limited interutterance variation of fundamental frequency, and phonetic…

  9. Psychic Duality of Afro-Americans in Novels of W. E. B. DuBois.

    ERIC Educational Resources Information Center

    Stewart, James B.

    1983-01-01

    Examines treatment of "double-consciousness" in DuBois' novels in the light of (1) the extent to which it provides Blacks with a vision unavailable to non-Blacks; (2) the nature and strength of cultural ties that bind Blacks together; and (3) the process by which liberation of the Black psyche is achieved. (CMG)

  10. The Legacy of W. E. B. DuBois for Contemporary Black Studies.

    ERIC Educational Resources Information Center

    Stewart, James B.

    1984-01-01

    Analyzes the writings and career of W.E.B. DuBois to reconstruct an historical exemplar for Black Studies. Emphasizes the diversity of the leader's thought and roles in relation to the various methodologies used in Black Studies. Argues that such "restoration" work is needed to facilitate further maturation of the discipline. (KH)

  11. Student Profile, College of DuPage, Fall 1986-1989. Topical Paper.

    ERIC Educational Resources Information Center

    Rice, Gary

    Prepared to provide staff with a more comprehensive profile of the student body of the College of DuPage (COD), Illinois, this report looks at changes in the student body and its increasing diversity over the last 5 years, and raises issues for staff discussion and planning. The report is divided into 18 sections, each consisting of an…

  12. College of DuPage District 502 Educational Needs Assessment (Total Sample Summary).

    ERIC Educational Resources Information Center

    Rice, Gary

    In spring 1987, the Gallup Organization conducted a telephone survey for the College of DuPage (COD) in Illinois to determine community perceptions of the college's role in the community; community awareness of COD and its competitors; perceptions of current college services; importance of factors in selecting an educational program; interest in…

  13. Kyste épidermoïde du testicule : Étude de cas

    PubMed Central

    Diarra, Alkadri; Elammari, Jalal Eddine; Kassogue, Amadou; El Fassi, Mohammed Jamal; Farih, My Hassan

    2013-01-01

    Résumé Le kyste épidermoïde (KE) du testicule est une tumeur bénigne rare. Le diagnostic peut être évoqué par l’échographie et l’IRM. En cas de lésion unique de petite taille, il est possible d’effectuer une chirurgie conservatrice. Ce traitement nécessite une confirmation anatomopathologique. Le présent article fait état de l’observation d’un patient de 34 ans ayant été admis en consultation d’urologie pour désir d’enfant. Le diagnostic de KE associé à une varicocèle gauche a été retenu. L’énucléation du kyste avec cure de varicocèle a été réalisée sans complications postopératoires. Une revue de la littérature nous a permis de mettre en évidence les différents aspects du KE du testicule et les méthodes thérapeutiques envisageables. PMID:24282476

  14. College of DuPage Information Technology Plan, Fiscal Year 1994-95.

    ERIC Educational Resources Information Center

    College of DuPage, Glen Ellyn, IL.

    Building upon four previous planning documents for computing at College of DuPage in Illinois, this plan for fiscal year 1995 (FY95) provides a starting point for future plans to address all activities that relate to the use of information technology on campus. The FY95 "Information Technology Plan" is divided into six sections, each providing an…

  15. Traitement chirurgical des fractures articulaires du calcanéum par plaque vissée

    PubMed Central

    Hammou, Nassreddine; Abid, Hatim; Shimi, Mohammed; El Ibrahimi, Abdelhalim; El Mrini, Abdelmajid

    2015-01-01

    Les fractures du calcanéum sont peu fréquentes mais le plus souvent graves. Le traitement chirurgical par plaque vissée est ardemment défendu. L'objectif de notre travail rétrospectif est d’évaluer les résultats du traitement chirurgical des fractures articulaires du calcanéum à travers une série de 12 patients opérée aux service d'orthopédie du CHU Hassan II de Fès sur une durée de 3 ans, et les comparer aux données de la littérature. L’âge moyen dans notre série était de 34 ans, le geste opératoire était réalisé au 7ème jour. Tous nos patient ont bénéficie d'une réduction à foyer ouvert avec une ostéosynthèse par plaques vissées. Le recul moyen était de 12 mois et les résultats fonctionnels ont été évaluer selon le score de Kitaoka. PMID:26161214

  16. Traitement des Images pour la Reconnaissance de Formes EN Presence de Bruit Dependant du Signal

    NASA Astrophysics Data System (ADS)

    Terrillon, Jean-Christophe

    En traitement d'images, tres peu de recherches ont jusqu'a present considere le probleme de la reconnaissance de formes en presence de bruit dependant du signal. L'originalite de ce travail reside d'une part dans l'etude de la reconnaissance de formes par correlation, invariante sous translation et invariante simultanement sous rotation et translation, en presence de bruit dependant du signal et, d'autre part, dans le developpement de nouvelles methodes de traitement d'images qui preservent la reconnaissance en presence du bruit lorsque les methodes existantes ont echoure. Nous considerons principalement le speckle, qui peut se manifester dans les correlateurs optiques operant en eclairement coherent. Les nouvelles methodes que nous proposons consistent en un pre-traitement des images bruitees base sur la theorie de l'estimation. Au moyen de simulations numeriques et d'une analyse statistique, nous montrons les avantages du pre-traitement, en particulier pour la reconnaissance avec les filtres de correlation invariants sous rotation et translation.

  17. Of Faith and Fiction: Teaching W. E. B. Du Bois and Religion

    ERIC Educational Resources Information Center

    Sinitiere, Phillip Luke

    2012-01-01

    W. E. B. Du Bois (1868-1963) is widely known as a champion for the political rights of African Americans, founder of the National Association for the Advancement of Colored People (NAACP), aggressive advocate of Pan-Africanism, staunch supporter of female suffrage, and one of the creative forces behind the Harlem Renaissance. Further still, Du…

  18. W.E.B. DuBois's Challenge to Scientific Racism.

    ERIC Educational Resources Information Center

    Taylor, Carol M.

    1981-01-01

    Proposes that a direct and authoritative challenge to the scientific racism of the late eighteenth and early twentieth centuries was urgently needed, and was one of the leading rhetorical contributions of W.E.B. DuBois. Specifically examines three issues: social Darwinism, the eugenics movement, and psychologists' measurement of intelligence.…

  19. Office Automation Pilot: A Paperless Approach at College of DuPage.

    ERIC Educational Resources Information Center

    Carlson, Bart

    The pilot project described in this report was undertaken by the College of DuPage (CD) to increase the clerical efficiency of seven administrative offices through the installation of a computerized word processing and data transmission system. The first section of the report provides background information detailing: the history of computer…

  20. Restructuring dynamics of DU 145 and LNCaP prostate cancer spheroids.

    PubMed

    Song, Hong; Jain, Shamik K; Enmon, Richard M; O'Connor, Kim C

    2004-01-01

    Neoplastic cells acquire multidrug resistance as they assemble into multicellular spheroids. Image analysis and Monte Carlo simulation provided an insight into the adhesion and motility events during spheroid restructuring in liquid-overlay culture of DU 145 and LNCaP human prostate cancer cells. Irregularly shaped, two-dimensional aggregates restructured through incremental cell movements into three-dimensional spheroids. Of the two cultures examined, restructuring was more pronounced for DU 145 aggregates. Motile DU 145 cells formed spheroids with a minimum cell overlay of 30% for 25-mers as estimated by simulation versus 5% for adhesive LNCaP cells in aggregates of the same size. Over 72 h, the texture ratio increased from 0.55 +/- 0.05 for DU 145 aggregates with projected areas exceeding 2000 microm2 to a value approaching 0.75 +/- 0.02 (P < 0.05). For LNCaP aggregates of comparable size, the increase in texture ratio was more modest, less than 15% during the same time period (P < 0.05). Combined, these data suggest that motility events govern the overall rate of spheroid restructuring. This information has application to the chemosensitization of solid tumors and kinetic modeling of spheroid production. PMID:15723561

  1. Acceptabilité du test VIH proposé aux nourrissons dans les services pédiatriques, en Côte d'Ivoire, Significations pour la couverture du diagnostic pédiatrique

    PubMed Central

    Oga, Maxime; Brou, Hermann; Dago-Akribi, Hortense; Coffie, Patrick; Amani-Bossé, Clarisse; Ékouévi, Didier; Yapo, Vincent; Menan, Hervé; Ndondoki, Camille; Timité-Konan, M.; Leroy, Valériane

    2014-01-01

    Résumé Problème: Le dépistage VIH chez les enfants a rarement été au centre des préoccupations des chercheurs. Quand le dépistage pédiatrique a retenu l'attention, cela a été pour éclairer seulement sur les performances diagnostiques en ignorant même que le test pédiatrique comme bien d'autres peut s'accepter ou se refuser. Cet article met au cœur de son analyse les raisons qui peuvent expliquer qu'on accepte ou qu'on refuse de faire dépister son enfant. Objectif: Etudier chez les parents, les mères, les facteurs explicatifs de l'acceptabilité du test VIH des nourrissons de moins de six mois. Méthodes: Entretien semi-directif à passages répétés avec les parents de nourrissons de moins de six mois dans les formations sanitaires pour la pesée/vaccination et les consultations pédiatriques avec proposition systématique d'un test VIH pour leur nourrisson. Résultats: Nous retenons que la réalisation effective du test pédiatrique du VIH chez le nourrisson repose sur trois éléments. Primo, le personnel de santé par son discours (qui dénote de ses connaissances et perceptions même sur l'infection) orienté vers les mères influence leur acceptation ou non du test. Secundo, la mère qui par ses connaissances et perceptions même sur le VIH, dont le statut particulier, l'impression de bien-être chez elle et son enfant influence toute réalisation du test pédiatrique VIH. Tertio, l'environnement conjugal de la mère, particulièrement caractérisé par les rapports au sein du couple, sur la facilité de parler du test VIH et sa réalisation chez les deux parents ou chez la mère seulement sont autant de facteurs qui influencent la réalisation effective du dépistage du VIH chez l'enfant. Le principe préventif du VIH, et le désir de faire tester l'enfant ne suffisent pas à eux seuls pour aboutir à sa réalisation effective, selon certaines mères confrontées au refus du conjoint. A l'opposé, les autres mères refusant la r

  2. Analyse de la prise en charge du nouveau-né dans le cadre de la stratégie nationale de subvention des accouchements et des soins obstétricaux et néonatals d'urgence au Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou (Burkina Faso)

    PubMed Central

    Ouédraogo, Solange Odile Yugbaré; Yougbaré, Nestor; Kouéta, Fla; Dao; Ouédraogo, Moussa; Lougué, Claudine; Ludovic, Kam; Traoré, Ramata Ouédraogo; Yé, Diarra

    2015-01-01

    Introduction Il s'agit d'analyser la prise en charge du nouveau-né dans le cadre de la stratégie na-tionale de subvention des accouchements et des soins obstétricaux et néonatals d'urgence mis en place par le gouvernement du Burkina Faso en 2006. Méthodes Nous avons menée une étude à visée descriptive et analytique comportant un volet ré-trospectif du 01 janvier 2006 au 31 décembre 2010 portant sur les paramètres épidémiologiques, cliniques des nouveau-nés hospitalisés et un volet prospectif du 3 octobre 2011 au 29 février 2012 par une entrevue des accompagnateurs des nouveau-nés et des prestataires des services de santé. Résultats Les hospitalisations ont augmenté de 43,65% entre 2006 à 2010 Le taux de mortalité néo-natale hospitalière qui était de 11,04% a connu une réduction moyenne annuelle de 3,95%. L'entrevue a porté sur 110 accompagnateurs et 76 prestataires. La majorité des prestataires (97,44%) et des ac-compagnateurs (88,18%) étaient informés de la stratégie mais n'avait pas une connaissance exacte de sa définition. Les prestataires (94,74%) ont signalé des ruptures de médicaments, consommables médicaux et des pannes d’ appareils de laboratoire et d'imagerie. Parmi les accompagnateurs (89%) disaient être satisfaits des services offerts et (72,89%) trouvaient les coûts abordables mais évoquaient les difficultés du transport. Conclusion: La subvention a amélioré la prise en charge du nou-veau-né mais son optimisation nécessiterait une meilleur information et implication de tous les acteurs. Conclusion La subvention a amélioré la prise en charge du nouveau-né mais son optimisation nécessiterait une meilleur information et implication de tous les acteurs. PMID:26161166

  3. Etude des facteurs de risque du retard de croissance intra-utérin à Lubumbashi

    PubMed Central

    Moyambe, Jules Ngwe Thaba; Bernard, Pierre; Khang'Mate, Faustin; Nkoy, Albert Mwembo Tambwe A; Mukalenge, Faustin Chenge; Makanda, Daudet; Twite, Eugene; Ndudula, Arthur Munkana; Lubamba, Cham; Kadingi, Arnauld Kabulu; Kayomb, Mutach; Kayamba, Prosper Kalenga Muenze

    2013-01-01

    Introduction Dans notre milieu, il n'existe aucune politique de prévention du Retard de Croissance Intra-Utérin (RCIU) clairement défini. L'objectif de ce travail était d'identifier les facteurs de risque de RCIU afin de proposer une stratégie de lutte contre cette pathologie en agissant surtout sur des facteurs pouvant faire l'objet d'une action préventive. Méthodes Une étude cas-témoins a été menée dans 11 centres hospitaliers de Lubumbashi en République Démocratique du Congo, de Janvier 2010 à Juin 2011, dans le but d'identifier les facteurs de risque du retard de croissance intra-utérin (RCIU). Au total 420 gestantes (cas et témoins) avec grossesse monofoetale d'au moins 24 semaines d'aménorrhée ont été inclues dans l'étude. Les cas correspondaient aux gestantes dont le poids du fœtus était resté inférieur au 10 eme percentile des courbes de référence d'Alexander, après 2 échographies successives réalisées à intervalle de 4 semaines. Les témoins correspondaient aux gestantes dont le poids du fœtus était supérieur ou égal au 10 eme percentile de mêmes courbes. A chaque cas a été apparié un témoin de même parité porteur d'une grossesse de même âge. Résultats L'analyse univariée a identifié comme facteurs de risque: la taille maternelle. Conclusion L'amélioration du niveau socio-économique des populations, la lutte contre le paludisme et les consultations prénatales mieux organisées couplées à une meilleure éducation sanitaire et nutritionnelle peuvent contribuer sensiblement à la réduction de la fréquence du RCIU à Lubumbashi. PMID:23504392

  4. Partial purification and characterization of bacteriocin produced by Enterococcus faecalis DU10 and its probiotic attributes.

    PubMed

    Perumal, Venkatesh; Repally, Ayyanna; Dasari, Ankaiah; Venkatesan, Arul

    2016-10-01

    A novel bacteriocin produced by avian duck isolated lactic acid bacterium Enterococcus faecalis DU10 was isolated. This bacteriocin showed a broad spectrum of antibacterial activity against important food-borne pathogens and was purified by size exclusion chromatography followed by reverse-phase high-performance liquid chromatography in a C-18 column. Tricine-SDS PAGE revealed the presence of a band with an estimated molecular mass of 6.3 kDa. The zymogram clearly linked the antimicrobial activity with this band. This result was further confirmed by mass-assisted laser desorption ionization time-of-flight mass spectrometry, since a sharp peak corresponding to 6.313 kDa was detected and the functional groups were revealed by Fourier transform infrared spectroscopy. Bacteriocin DU10 activity was found sensitive to proteinase-K and pepsin and partially affected by trypsin and α-chymotrypsin. The activity of bacteriocin DU10 was partially resistant to heat treatments ranging from 30 to 90°C for 30 min. It also withstood a treatment at 121°C for 10 min. Cytotoxicity of bacteriocin DU10 by methyl-thiazolyl-diphenyl-tetrazolium bromide assay showed that the viability of HT-29 and HeLa cells decreased 60 ± 0.7% and 43 ± 4.8%, respectively, in the presence of 3,200 AU/mL of bacteriocin. The strain withstood 0.3% w/v of bile oxgall and pH 2 affected the bacterial growth between 2 and 4 hr of incubation. Adhesion properties examined with HT-29 cell line showed 69.85% initial population of strain E. faecalis DU10, which was found to be strongly adhered to this cell line. These results conclude bacteriocin DU10 may be used as a potential biopreservative and E. faecalis DU10 may be used as a potential probiont to control Salmonella infections. PMID:26786752

  5. Partial purification and characterization of bacteriocin produced by Enterococcus faecalis DU10 and its probiotic attributes.

    PubMed

    Perumal, Venkatesh; Repally, Ayyanna; Dasari, Ankaiah; Venkatesan, Arul

    2016-10-01

    A novel bacteriocin produced by avian duck isolated lactic acid bacterium Enterococcus faecalis DU10 was isolated. This bacteriocin showed a broad spectrum of antibacterial activity against important food-borne pathogens and was purified by size exclusion chromatography followed by reverse-phase high-performance liquid chromatography in a C-18 column. Tricine-SDS PAGE revealed the presence of a band with an estimated molecular mass of 6.3 kDa. The zymogram clearly linked the antimicrobial activity with this band. This result was further confirmed by mass-assisted laser desorption ionization time-of-flight mass spectrometry, since a sharp peak corresponding to 6.313 kDa was detected and the functional groups were revealed by Fourier transform infrared spectroscopy. Bacteriocin DU10 activity was found sensitive to proteinase-K and pepsin and partially affected by trypsin and α-chymotrypsin. The activity of bacteriocin DU10 was partially resistant to heat treatments ranging from 30 to 90°C for 30 min. It also withstood a treatment at 121°C for 10 min. Cytotoxicity of bacteriocin DU10 by methyl-thiazolyl-diphenyl-tetrazolium bromide assay showed that the viability of HT-29 and HeLa cells decreased 60 ± 0.7% and 43 ± 4.8%, respectively, in the presence of 3,200 AU/mL of bacteriocin. The strain withstood 0.3% w/v of bile oxgall and pH 2 affected the bacterial growth between 2 and 4 hr of incubation. Adhesion properties examined with HT-29 cell line showed 69.85% initial population of strain E. faecalis DU10, which was found to be strongly adhered to this cell line. These results conclude bacteriocin DU10 may be used as a potential biopreservative and E. faecalis DU10 may be used as a potential probiont to control Salmonella infections.

  6. Cancer du sein de l'homme: à propos de 6 cas

    PubMed Central

    Laabadi, Kamilia; Jayi, Sofia; Alaoui, Fatimazohra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, My Abdelilah; Hassani, Karim Ibn Majdoub; Laalim, Said Ait; Anoun, Hicham; Toughrai, Imane; Mazaz, Khalid

    2013-01-01

    Le but de ce travail était d'analyser les caractéristiques cliniques, histologiques, thérapeutiques et pronostiques du cancer du sein chez l'homme. Il s'agissait d'une étude rétrospective portant sur six patients colligés au service de gynécologie obstétrique II, CHU Hassan II durant la période 2009-2012. L’âge moyen de nos patients est de 65.3 ans. Il s'agit dans 83.3% des cas, d'une tumeur rétroaréolaire dont la taille moyenne est de 44.16 mm. Nous avons retrouvé 4 (66.7%) T4, 1 (16.7%) T3 et dans un cas, une tumeur inclassable. Le type histologique le plus représenté est le carcinome canalaire infiltrant (66.7%). Le taux d'envahissement ganglionnaire axillaire est de 66.7%. L'hormonodépendance de ces tumeurs est prouvée dans 100% des cas. La survie à cinq ans est en cours d’évaluation. L'envahissement ganglionnaire, l'invasion du derme, le stade clinique TNM sont des facteurs qui influencent significativement la survenue de métastases. Aucun de ces facteurs de risque n'est apparu significatif en termes de survie globale. Le cancer du sein chez l'homme est une maladie rare (environ 1% des cancers du sein) au pronostic sombre. Le diagnostic est le plus souvent tardif et les lésions sont traitées à des stades avancés. PMID:24711870

  7. Long-range transport of volcanic SO2 over Northern India

    NASA Astrophysics Data System (ADS)

    Mallik, Chinmay; Joshi, Hema; Chand, D.; Lal, Shyam; Naja, Manish; Venkataramani, S.; Pant, P.

    2012-07-01

    Anthropogenic activities contribute to more than 70% of global sulfur dioxide (SO2) emissions. Among the natural sources of SO2, volcanic emissions can be significant but sporadic contributors. Apart from releasing a plethora of pollutant gases, volcanoes can also impact atmospheric temperatures and radiation balance as was observed after El Chichon (1982) and Mt. Pinatubo (1991) eruptions. The present study deals with episodes of long-range transport of SO2 from Africa to Northern India using multiple satellite observations. Monthly averaged SO2 from OMI were of the order of 0.6-0.9 DU during November, 2008 over the Indo-Gangetic Plain (IGP). In contrast, SO2 monthly averages retrieved from observations across different locations over North India had never exceeded 0.3 DU during the six year period of 2005-2010. The columnar SO2 loadings were a factor of 10 higher than background levels over most of the IGP on the day of impact. These enhanced SO2 levels were, however, not reciprocated in satellite derived NO2 or CO columns, indicating transport from a non-anthropogenic source of SO2. Back-trajectory analysis revealed strong winds in the free troposphere, which originated from a volcanic eruption over Ethiopia. Wind streams and stable atmospheric conditions were conducive to the long-range transport of volcanic plume over the IGP. Increase in aerosol optical depths were observed both from ground-based measurements as well as satellite observations. A well separated layer of aerosols above the boundary layer was observed from CALIPSO, most likely as a result of this transport. Apart from known anthropogenic sources, the additional transport of volcanic SO2 over the IGP region would have implications to air quality and radiation balance over this region. Details of this episode of transport in terms of meteorology and dynamics will be presented during the assembly.

  8. EBS Radionuclide Transport Abstraction

    SciTech Connect

    J. Prouty

    2006-07-14

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment (TSPA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers advective transport and diffusive transport

  9. Transportation technology at Sandia

    SciTech Connect

    1994-12-31

    Industrial and military activities in the US produce large amounts of hazardous mixed waste, which includes both radioactive and toxic substances. The already overburdened environment is faced with the task of safely disposing of these complex wastes. A very important aspect of this effort is the safe and economical transportation of radioactive and toxic chemical wastes to projected repositories. Movement of wastes to the repository sites is accomplished by a combination of truck, rail, ship, and air. The DOE directs transportation activities including cask development technology for use in single or multimode transport. Sandia National Laboratories` Transportation Technology programs provide the technology and know-how to support DOE in achieving safe, efficient, and economical packaging and transportation of nuclear and other hazardous waste materials. This brochure describes the Transportation Technology programs and the specialized techniques and capabilities they offer to prospective users.

  10. Payload transportation system study

    NASA Technical Reports Server (NTRS)

    1976-01-01

    A standard size set of shuttle payload transportation equipment was defined that will substantially reduce the cost of payload transportation and accommodate a wide range of payloads with minimum impact on payload design. The system was designed to accommodate payload shipments between the level 4 payload integration sites and the launch site during the calendar years 1979-1982. In addition to defining transportation multi-use mission support equipment (T-MMSE) the mode of travel, prime movers, and ancillary equipment required in the transportation process were also considered. Consistent with the STS goals of low cost and the use of standardized interfaces, the transportation system was designed to commercial grade standards and uses the payload flight mounting interfaces for transportation. The technical, cost, and programmatic data required to permit selection of a baseline system of MMSE for intersite movement of shuttle payloads were developed.

  11. Coal transportation and handling

    SciTech Connect

    Mahr, D.

    1985-11-01

    Coal transport is represented here as a major cost in energy production. The system, itself, is complex but thorough analysis can produce positive results. Minemouth costs increase as do transportation costs, and the understanding of the system can lead to costs control. Short hauls represent major savings, longer ones more expenses. Some terminals blend various coals to benefit power companies, according to need. Specific examples are given, as are differentials between shipping and railroad transportation. For instance, significant savings can be achieved between railroad-owned and transporter-owned railcar.

  12. Transportation Baseline Schedule

    SciTech Connect

    Fawcett, Ricky Lee; John, Mark Earl

    2000-01-01

    The “1999 National Transportation Program - Transportation Baseline Report” presents data that form a baseline to enable analysis and planning for future Department of Energy (DOE) Environmental Management (EM) waste/material transportation. The companion “1999 Transportation ‘Barriers’ Analysis” analyzes the data and identifies existing and potential problems that may prevent or delay transportation activities based on the data presented. The “1999 Transportation Baseline Schedule” (this report) uses the same data to provide an overview of the transportation activities of DOE EM waste/materials. This report can be used to identify areas where stakeholder interface is needed, and to communicate to stakeholders the quantity/schedule of shipments going through their area. Potential bottlenecks in the transportation system can be identified; the number of packages needed, and the capacity needed at receiving facilities can be planned. This report offers a visualization of baseline DOE EM transportation activities for the 11 major sites and the “Geologic Repository Disposal” site (GRD).

  13. Thermodynamics of ABC transporters.

    PubMed

    Zhang, Xuejun C; Han, Lei; Zhao, Yan

    2016-01-01

    ABC transporters form the largest of all transporter families, and their structural study has made tremendous progress over recent years. However, despite such advances, the precise mechanisms that determine the energy-coupling between ATP hydrolysis and the conformational changes following substrate binding remain to be elucidated. Here, we present our thermodynamic analysis for both ABC importers and exporters, and introduce the two new concepts of differential-binding energy and elastic conformational energy into the discussion. We hope that the structural analysis of ABC transporters will henceforth take thermodynamic aspects of transport mechanisms into account as well.

  14. Space Transportation Propulsion Systems

    NASA Technical Reports Server (NTRS)

    Liou, Meng-Sing; Stewart, Mark E.; Suresh, Ambady; Owen, A. Karl

    2001-01-01

    This report outlines the Space Transportation Propulsion Systems for the NPSS (Numerical Propulsion System Simulation) program. Topics include: 1) a review of Engine/Inlet Coupling Work; 2) Background/Organization of Space Transportation Initiative; 3) Synergy between High Performance Computing and Communications Program (HPCCP) and Advanced Space Transportation Program (ASTP); 4) Status of Space Transportation Effort, including planned deliverables for FY01-FY06, FY00 accomplishments (HPCCP Funded) and FY01 Major Milestones (HPCCP and ASTP); and 5) a review current technical efforts, including a review of the Rocket-Based Combined-Cycle (RBCC), Scope of Work, RBCC Concept Aerodynamic Analysis and RBCC Concept Multidisciplinary Analysis.

  15. UZ Colloid Transport Model

    SciTech Connect

    M. McGraw

    2000-04-13

    The UZ Colloid Transport model development plan states that the objective of this Analysis/Model Report (AMR) is to document the development of a model for simulating unsaturated colloid transport. This objective includes the following: (1) use of a process level model to evaluate the potential mechanisms for colloid transport at Yucca Mountain; (2) Provide ranges of parameters for significant colloid transport processes to Performance Assessment (PA) for the unsaturated zone (UZ); (3) Provide a basis for development of an abstracted model for use in PA calculations.

  16. WASTE PACKAGE TRANSPORTER DESIGN

    SciTech Connect

    D.C. Weddle; R. Novotny; J. Cron

    1998-09-23

    The purpose of this Design Analysis is to develop preliminary design of the waste package transporter used for waste package (WP) transport and related functions in the subsurface repository. This analysis refines the conceptual design that was started in Phase I of the Viability Assessment. This analysis supports the development of a reliable emplacement concept and a retrieval concept for license application design. The scope of this analysis includes the following activities: (1) Assess features of the transporter design and evaluate alternative design solutions for mechanical components. (2) Develop mechanical equipment details for the transporter. (3) Prepare a preliminary structural evaluation for the transporter. (4) Identify and recommend the equipment design for waste package transport and related functions. (5) Investigate transport equipment interface tolerances. This analysis supports the development of the waste package transporter for the transport, emplacement, and retrieval of packaged radioactive waste forms in the subsurface repository. Once the waste containers are closed and accepted, the packaged radioactive waste forms are termed waste packages (WP). This terminology was finalized as this analysis neared completion; therefore, the term disposal container is used in several references (i.e., the System Description Document (SDD)) (Ref. 5.6). In this analysis and the applicable reference documents, the term ''disposal container'' is synonymous with ''waste package''.

  17. FY2008 Report on GADRAS Radiation Transport Methods.

    SciTech Connect

    Mattingly, John.; Mitchell, Dean J; Harding, Lee T.; Varley, Eric S.; Hilton, Nathan R.

    2008-10-01

    The primary function of the Gamma Detector Response and Analysis Software (GADRAS) is the solution of inverse radiation transport problems, by which the con-figuration of an unknown radiation source is inferred from one or more measured radia-tion signatures. GADRAS was originally developed for the analysis of gamma spec-trometry measurements. During fiscal years 2007 and 2008, GADRAS was augmented to implement the simultaneous analysis of neutron multiplicity measurements. This report describes the radiation transport methods developed to implement this new capability. This work was performed at the direction of the National Nuclear Security Administration's Office of Nonproliferation Research and Development. It was executed as an element of the Proliferation Detection Program's Simulation, Algorithm, and Modeling element. Acronyms BNL Brookhaven National Laboratory CSD Continuous Slowing-Down DU depleted uranium ENSDF Evaluated Nuclear Structure Data Files GADRAS Gamma Detector Response and Analysis Software HEU highly enriched uranium LANL Los Alamos National Laboratory LLNL Lawrence Livermore National Laboratory NA-22 Office of Nonproliferation Research and Development NNDC National Nuclear Data Center NNSA National Nuclear Security Administration ODE ordinary differential equation ONEDANT One-dimensional diffusion accelerated neutral particle transport ORNL Oak Ridge National Laboratory PARTISN Parallel time-dependent SN PDP Proliferation Detection Program RADSAT Radiation Scenario Analysis Toolkit RSICC Radiation Safety Information Computational Center SAM Simulation, Algorithms, and Modeling SNL Sandia National Laboratories SNM special nuclear material ToRI Table of Radioactive Isotopes URI uniform resource identifier XML Extensible Markup Language

  18. Étude théorique et expérimentale du transfert du dioctyl phtalate à partir d'un disque de PVC plastifié plongé dans une huile comestible

    NASA Astrophysics Data System (ADS)

    Djilani, S.-E.; Toubal, A. A.; Messadi, D.

    1998-10-01

    When polymer and liquid are contacted with each other, as in packaging, some mass exchanges may occur, which constitute a major drawback when the liquid is a foodstuff or blood. However, these mass transfers in the polymers can appear as very interesting from the industrial point of view, if one is able to use and control them. It is then necessary to have a good knowledge of these transfer processes which are controlled by diffusion. Dioctyl phthalate (DOP) migration into an edible oil was studied under worst conditions: high plasticization level (50% by weight) and temperature(30 circC). The quantitative analysis of DOP in a such complex liquid medium and in the PVC itself was made easy by the use of the radioactive tracer technique. A simplified mathematical model, obtained by neglecting the oil transport in the PVC, was evaluated. This model based on the research of a finite differences explicit solution allows to reproduce for the DOP, the concentration profiles in the polymer and the kinetics of transfer in the oil, with a P-value ≥ 0.001. La mise en contact polymère-liquide se traduit généralement par des échanges de matière entre les 2 milieux considérés, ce qui constitue un inconvénient majeur lorsque le liquide est un aliment ou le sang. Cependant, ces transferts de matière dans les polymères peuvent apparaître comme très intéressants sur le plan industriel, si l'on est capable de les utiliser et de les contrôler. Il est donc nécessaire d'avoir une bonne connaissance de ces processus de transfert qui sont contrôlés par diffusion. Nous avons étudié la migration du dioctyl phtalate (DOP) dans une huile comestible en nous plaçant dans les conditions les plus défavorables: taux de plastification (50% en poids) et température (30°C) élevés. L'analyse quantitative du DOP dans un milieu liquide aussi complexe et dans le PVC lui- même a été facilitée par l'utilisation de la technique des traceurs radioactifs. Un modèle math

  19. Agrobacterium radiobacter and related organisms take up fructose via a binding-protein-dependent active-transport system.

    PubMed

    Williams, S G; Greenwood, J A; Jones, C W

    1995-10-01

    Washed cells of Agrobacterium radiobacter prepared from a fructose-limited continuous culture (D 0.045 h-1) transported D(-)[U-14C]fructose in a linear manner for up to 4 min at a rate several-fold higher than the rate of fructose utilization by the growing culture. D(-)[U-14C]Fructose transport exhibited a high affinity for fructose (KT < 1 microM) and was inhibited to varying extents by osmotic shock, by the uncoupling agent carbonyl cyanide p-trifluoromethoxyphenylhydrazone, and by unlabelled sugars (D-fructose/D-mannose > D-ribose > D-sorbose > D-glucose/D-galactose/D-xylose; no inhibition by D-arabinose). Prolonged growth of A. radiobacter in fructose-limited continuous culture led to the selection of a novel strain (AR100) which overproduced a fructose-binding protein (FBP) and showed an increased rate of fructose transport. FBP was purified from osmotic-shock fluid using anion-exchange fast protein liquid chromatography (FPLC). The monomeric protein (M(r) 34,200 by SDS-PAGE and 37,700 by gel-filtration FPLC) bound D-[U-14C]-fructose stoichiometrically (1.17 nmol nmol FBP-1) and with high affinity (KD 0.49 microM) as shown by equilibrium dialysis. Binding of D-[U-14C]fructose by FBP was variably inhibited by unlabelled sugars (D-fructose/D-mannose > D-ribose > D-sorbose; no inhibition by D-glucose, D-galactose or D-arabinose). The N-terminal amino acid sequence of FBP (ADTSVCLI-) was similar to that of several sugar-binding proteins from other species of bacteria. Fructose transport and FBP were variably induced in batch cultures of A. radiobacter by growth on different carbon sources (D-fructose > D-ribose/D-mannose > D-glucose; no induction by succinate). An immunologically similar protein to FBP was produced by Agrobacterium tumefaciens and various species of Rhizobium following growth on fructose. It is concluded that fructose is transported into A. radiobacter and related organisms via a periplasmic fructose/mannose-binding-protein-dependent active-transport

  20. Characterization of DuPont 9015, aqueous processable dry film photoresist for printed wiring boards. Topical report

    SciTech Connect

    Goldammer, S.

    1995-04-01

    This report describes the evaluation of DuPont`s Riston 9015, fully aqueous processable dry film photoresist as a mask for gold plating, tin/lead plating, and print and etch patterning for printed circuit board products.

  1. Technology Demonstration Summary. DuPont/Oberlin Microfiltration System. Palmerton, Pennsylvania (EPA/540/S5-90/007)

    EPA Science Inventory

    In April and May 1990, the U.S. Environmental Protection Agency (EPA), under the Superfund Innovative Technology Evaluation (SITE) program, demonstrated DuPont/Oberlin's microfiltration system at the Palmerton Zinc Superfund (PZS) site In Palmerton, Pennsylvania. The microfiltr...

  2. Acceptabilité du test VIH proposé aux nourrissons dans les services pédiatriques, en Côte d'Ivoire, Significations pour la couverture du diagnostic pédiatrique

    PubMed Central

    Oga, Maxime; Brou, Hermann; Dago-Akribi, Hortense; Coffie, Patrick; Amani-Bossé, Clarisse; Ékouévi, Didier; Yapo, Vincent; Menan, Hervé; Ndondoki, Camille; Timité-Konan, M.; Leroy, Valériane

    2014-01-01

    Résumé Problème: Le dépistage VIH chez les enfants a rarement été au centre des préoccupations des chercheurs. Quand le dépistage pédiatrique a retenu l'attention, cela a été pour éclairer seulement sur les performances diagnostiques en ignorant même que le test pédiatrique comme bien d'autres peut s'accepter ou se refuser. Cet article met au cœur de son analyse les raisons qui peuvent expliquer qu'on accepte ou qu'on refuse de faire dépister son enfant. Objectif: Etudier chez les parents, les mères, les facteurs explicatifs de l'acceptabilité du test VIH des nourrissons de moins de six mois. Méthodes: Entretien semi-directif à passages répétés avec les parents de nourrissons de moins de six mois dans les formations sanitaires pour la pesée/vaccination et les consultations pédiatriques avec proposition systématique d'un test VIH pour leur nourrisson. Résultats: Nous retenons que la réalisation effective du test pédiatrique du VIH chez le nourrisson repose sur trois éléments. Primo, le personnel de santé par son discours (qui dénote de ses connaissances et perceptions même sur l'infection) orienté vers les mères influence leur acceptation ou non du test. Secundo, la mère qui par ses connaissances et perceptions même sur le VIH, dont le statut particulier, l'impression de bien-être chez elle et son enfant influence toute réalisation du test pédiatrique VIH. Tertio, l'environnement conjugal de la mère, particulièrement caractérisé par les rapports au sein du couple, sur la facilité de parler du test VIH et sa réalisation chez les deux parents ou chez la mère seulement sont autant de facteurs qui influencent la réalisation effective du dépistage du VIH chez l'enfant. Le principe préventif du VIH, et le désir de faire tester l'enfant ne suffisent pas à eux seuls pour aboutir à sa réalisation effective, selon certaines mères confrontées au refus du conjoint. A l'opposé, les autres mères refusant la r

  3. Effects of HPV-16 infection on hypopharyngeal squamous cell carcinoma and FaDu cells.

    PubMed

    Lu, Wuhao; Feng, Long; Li, Ping; Wang, Yuanyuan; Du, Yuwen; Chen, Xiaonan; Wu, Shujun; Zhao, Guoqiang; Lou, Weihua

    2016-01-01

    Hypopharyngeal squamous cell carcinoma is a common type of malignant tumor among head and neck squamous cell carcinomas (HNSCCs). Heavy smoking and/or drinking is associated with the development of HNSCC. However, HNSCC also occurs in individuals that do not drink or smoke, possibly due to infection with the human papilloma virus (HPV). HPV-16 has been shown to be closely associated with the occurrence of several types of cancers. However, its role in hypopharyngeal squamous cell carcinoma remains unclear. In the present study, we investigated the effects of HPV-16 on hypopharyngeal squamous cell carcinoma and FaDu cells. Lentiviral vectors were used to establish FaDu cells that expressed the E6 and E7 proteins of HPV-16. We used quantitative reverse transcription-polymerase chain reaction (qRT-PCR) assays and western blotting to detect and determine the levels of expression for E6-E7 mRNAs and proteins. Cell Counting Kit-8 (CCK-8) assays, enzyme-linked immunosorbent assays (ELISA), Transwell assays, and flow cytometry were used to assess the effects of HPV-16 E6-E7 on the proliferation, invasion, metastasis and apoptosis of FaDu cells. Expression of microRNAs was analyzed by qRT-PCR. We found that the expression levels of HPV-16 E6-E7 were increased in FaDu cells transfected with the lentiviral vector compared with that observed in the control cells. In addition, the rates of apoptosis were decreased in the transfected cells, while proliferation was increased. The average numbers of cells penetrating the Matrigel were significantly higher than those for the controls. We detected miR-363 and miR-15a, and their expression levels were significantly increased in the HPV-16-positive patients and in FaDu cells expressing HPV-16 E6-E7. We found that HPV-16 E6-E7 appeared to inhibit apoptosis, and to increase cell proliferation, invasion and metastasis. Furthermore, miR-363 and miR-15a were overexpressed in the hypopharyngeal squamous cell carcinoma samples infected with

  4. Etude échographique du diamètre de l'enveloppe du nerf optique chez l'enfant noir africain sain

    PubMed Central

    de Tové, Kofi-Mensa Savi; Biaou, Olivier; Adedemy, Julien Didier; Fatigba, Olatoundji Holden; Yèkpè, Patricia; Boco, Vicentia; Agossou-Voyeme, Augustin Karl

    2014-01-01

    Introduction L'objectif de cette étude était de déterminer le diamètre échographique de l'enveloppe du nerf optique (DENO) dans une population d'enfants sains noirs Africains au Bénin. Méthodes Une étude transversale descriptive a été menée sur une période de 6mois. Le DENO a été mesuré chez 304 enfants sains. Deux mesures échographiques du DENO (coupe transversale et sagittale) ont été réalisées 3mm en arrière de la papille sur chaque œil. Le DENO d'un patient est égal à la moyenne des quatre mesures. Résultats L’âge moyen était de 35, 72 ± 35,38 mois et la sex-ratio H/F de 0,96. La mesure moyenne du DENO était de 3, 31±0,54mm avec des extrêmes de 2,02 et de 4,44mm. Le DENO croît avec l’âge avec une moyenne corrélation significative (r = 0,58 et p < 0,0001). Cette croissance est plus marquée pendant les 48 premiers mois de vie. Il n'y avait pas de différence entre les garçons et les filles (p = 0, 45). Conclusion Les valeurs retrouvées dans cette étude ne diffèrent pas de ce qui est classiquement décrit dans les autres populations. Un DENO supérieur à 4,40 (IC 95%) doit être considéré comme anormal. PMID:25870740

  5. Superposition tridimensionnelle (3-D) sur la base du crâne pour l’évaluation longitudinale des effets de la croissance et du traitement

    PubMed Central

    Cevidanes, Lucia H.S.; Styner, Martin; Proffit, William R.; Ngom, Traduit par Papa Ibrahima

    2010-01-01

    RÉSUMÉ – Pour évaluer les modifications liées à la croissance ou au traitement, il est nécessaire de superposer les céphalogrammes successifs sur une structure stable. En céphalométrie bidimensionnelle (2-D), la base du crâne est souvent utilisée pour les superpositions parce que les changements qu’elle subit après le développement cérébral sont mineurs. Toutefois, sur les céphalogrammes de profil et de face, les points de repère basicraniens sont peu fiables. Dans cet article, nous présentons une nouvelle méthode de superposition tridimensionnelle (3-D) basée sur un enregistrement entièrement automatisé des intensités de voxels, au niveau de la surface de la base du crâne. Le progiciel utilisé permet l’évaluation quantitative des modifications qui apparaissent dans le temps, grâce au calcul de la distance euclidienne entre les surfaces du modèle tridimensionnel. Il permet également l’appréciation visuelle de l’emplacement et de l’importance des modifications au niveau des maxillaires, grâce à une surimpression graphique. Les modifications sont visualisées par comparaison à des tables de correspondance de couleur. On peut ainsi réaliser une étude détaillée des modes d’adaptation chez les patients dont la croissance et/ou le traitement ont provoqué des modifications squelettiques cliniquement significatives. PMID:19954732

  6. World heritage site - Bien du Patrimoine Mondial - Kluane/Wrangell-St. Elias/Glacier Bay/Tatshenshini-Alsek

    USGS Publications Warehouse

    Labay, Keith A.; Wilson, Frederic H.

    2004-01-01

    The four parks depicted on this map make up a single World Heritage Site that covers 24.3 million acres. Together, they comprise the largest internationally protected land-based ecosystem on the planet. The United Nations Educational, Scientific and Cultural Organization (UNESCO) established the World Heritage Program in 1972 for the identification and protection of the world?s irreplaceable natural and cultural resources. World Heritage Sites are important as storehouses of memory and evolution, as anchors for sustainable tourism and community, and as laboratories for the study and understanding of the earth and culture. This World Heritage Site protects the prominent mountain ranges of Kluane, Wrangell, Saint Elias, and Chugach. It includes many of the tallest peaks on the continent, the world's largest non-polar icefield, extensive glaciers, vital watersheds, and expanses of dramatic wilderness. [Les quatre parcs figurant sur cette carte ne constituent qu?un seul site du patrimoine mondial recouvrant plus de 99 millions de km2, ce qui en fait le plus grand ecosysteme terrestre protege par loi internationale. En 1972, L?UNESCO (l?organisation des Nations Unies pour les sciences, l'education et la culture) a etabli le programme du patrimoine mondial afin d?identifier et de proteger les ressources naturelles et culturelles irremplacables de notre plan?te. Si les sites du patrimoine mondial sont si importants c'est parce qu'ils representent a la fois des livres ouverts sur l?histoire de la Terre, le point de depart du tourisme durable et du developpement des collectivites, des laboratoires pour etudier et comprendre la nature et la culture. Ce site du patrimoine mondial assure la protection des chaines de montagnes de Kluane, Wrangell, Saint Elias, et Chugach. On y trouve plusieurs des plus hauts sommets du continent, le plus grand champ de glace non-polaire du monde, d?immenses glaciers, des bassins hydrologiques essentiels, et de la nature sauvage a perte de vue.

  7. Eucommia bark (Du-Zhong) improves diabetic nephropathy without altering blood glucose in type 1-like diabetic rats

    PubMed Central

    Niu, Ho-Shan; Liu, I-Min; Niu, Chiang-Shan; Ku, Po-Ming; Hsu, Chao-Tien; Cheng, Juei-Tang

    2016-01-01

    Background Eucommia bark, Eucommia ulmoides Oliver barks (Du-Zhong in Mandarin), is an herb used for renal dysfunction in Chinese traditional medicine. In an attempt to develop this herb as a treatment for diabetic nephropathy (DN), we investigated the effects of Du-Zhong on renal dysfunction in type 1-like diabetic rats. Methods Streptozotocin (STZ) was used to induce type 1-like diabetes in rats (STZ-diabetic rats). In addition to hyperglycemia, STZ-diabetic rats showed significant nephropathy, including higher plasma levels of blood urea nitrogen, creatinine, and renal fibrosis. Western blot analysis of renal cortical tissue was applied to characterize the changes in potential signals related to nephropathy. Results Oral administration of Du-Zhong (1 g/kg/day) to STZ-diabetic rats for 20 days not only decreased the plasma levels of blood urea nitrogen and creatinine but also improved renal fibrosis, whereas the plasma glucose level was not changed. The higher expressions of protein levels of transforming growth factor-beta (TGF-β) and connective tissue growth factor in diabetic rats were markedly attenuated by Du-Zhong. The increased phosphorylation of Smad2/3 in STZ-diabetic rats was also reduced by Du-Zhong. However, Du-Zhong cannot reverse the hyperglycemia-induced overproduction of signal transducers and activators of transcription 3 in the diabetic kidney. Conclusion Oral administration of Du-Zhong improves STZ-induced DN in rats by inhibiting TGF-β/Smad signaling and suppressing TGF-β/connective tissue growth factor expression. Therefore, active principle from Du-Zhong is suitable to develop as new agent for DN in the future. PMID:27041999

  8. Transport characteristics of urea transporter-B.

    PubMed

    Yang, Baoxue

    2014-01-01

    UT-B represents the major urea transporter in erythrocytes, in addition to being expressed in kidney descending vasa recta, brain, spleen, ureter, bladder, and testis. Expression of urea transporter UT-B confers high urea permeability to mammalian erythrocytes. Erythrocyte membranes are also permeable to various urea analogues, suggesting common transport pathways for urea and structurally similar solutes. UT-B is highly permeable to urea and the chemical analogues formamide, acetamide, methylurea, methylformamide, ammonium carbamate, and acrylamide, each with a Ps > 5.0 × 10(-6) cm/s at 10 °C. The amides formamide, acetamide, acrylamide, and butyramide efficiently diffuse across lipid bilayers. The urea analogues dimethylurea, acryalmide, methylurea, thiourea, and methylformamide inhibit UT-B-mediated urea transport by >60 % by a pore-blocking mechanism. UT-B is also a water channel in erythrocytes and has a single-channel water permeability that is similar to aquaporin-1. Whether UT-B is an NH3 channel still needs further study. Urea permeability (Purea) in erythrocytes differs between different mammals. Carnivores (dog, fox, cat) exhibit high Purea. In contrast, herbivores (cow, donkey, sheep) show much lower Purea. Erythrocyte Purea in human and pig (omnivores) was intermediate. Rodents and lagomorphs (mouse, rat, rabbit) have Purea intermediate between carnivores and omnivores. Birds that do not excrete urea and do not express UT-B in their erythrocytes have very low values. In contrast to Purea, water permeability is relatively similar in all mammals studied. This chapter will provide information about the transporter characteristics of UT-B. PMID:25298342

  9. Transport characteristics of urea transporter-B.

    PubMed

    Yang, Baoxue

    2014-01-01

    UT-B represents the major urea transporter in erythrocytes, in addition to being expressed in kidney descending vasa recta, brain, spleen, ureter, bladder, and testis. Expression of urea transporter UT-B confers high urea permeability to mammalian erythrocytes. Erythrocyte membranes are also permeable to various urea analogues, suggesting common transport pathways for urea and structurally similar solutes. UT-B is highly permeable to urea and the chemical analogues formamide, acetamide, methylurea, methylformamide, ammonium carbamate, and acrylamide, each with a Ps > 5.0 × 10(-6) cm/s at 10 °C. The amides formamide, acetamide, acrylamide, and butyramide efficiently diffuse across lipid bilayers. The urea analogues dimethylurea, acryalmide, methylurea, thiourea, and methylformamide inhibit UT-B-mediated urea transport by >60 % by a pore-blocking mechanism. UT-B is also a water channel in erythrocytes and has a single-channel water permeability that is similar to aquaporin-1. Whether UT-B is an NH3 channel still needs further study. Urea permeability (Purea) in erythrocytes differs between different mammals. Carnivores (dog, fox, cat) exhibit high Purea. In contrast, herbivores (cow, donkey, sheep) show much lower Purea. Erythrocyte Purea in human and pig (omnivores) was intermediate. Rodents and lagomorphs (mouse, rat, rabbit) have Purea intermediate between carnivores and omnivores. Birds that do not excrete urea and do not express UT-B in their erythrocytes have very low values. In contrast to Purea, water permeability is relatively similar in all mammals studied. This chapter will provide information about the transporter characteristics of UT-B.

  10. Transport Version 3

    2008-05-16

    The Transport version 3 (T3) system uses the Network News Transfer Protocol (NNTP) to move data from sources to a Data Reporisoty (DR). Interested recipients subscribe to newsgroups to retrieve data. Data in transport is protected by AES-256 and RSA cryptographic services provided by the external OpenSSL cryptographic libraries.

  11. Transportation: Topic Paper E.

    ERIC Educational Resources Information Center

    National Council on the Handicapped, Washington, DC.

    As one of a series of topic papers assessing federal laws and programs affecting persons with disabilities, this paper reviews the issue of transportation services. In the area of urban mass transit, four relevant pieces of legislation and public transportation accessibility regulations are cited, and cost issues are explored. Paratransit systems,…

  12. Issues in Pupil Transportation.

    ERIC Educational Resources Information Center

    Association of School Business Officials International, Reston, VA.

    The primary purpose of this book is to present the critical issues in pupil transportation that will confront pupil transportation supervisors in local school districts. The following issues are discussed: (1) demands for extended service from community pressure groups; (2) reductions in budget requests by governing bodies; (3) unrest among driver…

  13. Pupil Transportation Management.

    ERIC Educational Resources Information Center

    Miller, Anthony R.

    The safest means of transportation in the United States is the school bus fleet. Each school day, over 350,000 school buses transport about 22,000,000 children ages 3 to 21--from wheelchair pupils to varsity football players--to and from school in weather conditions ranging from those for Fairbanks, Alaska, to those typical of Cave Creek, Arizona.…

  14. Transport of sugars.

    PubMed

    Chen, Li-Qing; Cheung, Lily S; Feng, Liang; Tanner, Widmar; Frommer, Wolf B

    2015-01-01

    Soluble sugars serve five main purposes in multicellular organisms: as sources of carbon skeletons, osmolytes, signals, and transient energy storage and as transport molecules. Most sugars are derived from photosynthetic organisms, particularly plants. In multicellular organisms, some cells specialize in providing sugars to other cells (e.g., intestinal and liver cells in animals, photosynthetic cells in plants), whereas others depend completely on an external supply (e.g., brain cells, roots and seeds). This cellular exchange of sugars requires transport proteins to mediate uptake or release from cells or subcellular compartments. Thus, not surprisingly, sugar transport is critical for plants, animals, and humans. At present, three classes of eukaryotic sugar transporters have been characterized, namely the glucose transporters (GLUTs), sodium-glucose symporters (SGLTs), and SWEETs. This review presents the history and state of the art of sugar transporter research, covering genetics, biochemistry, and physiology-from their identification and characterization to their structure, function, and physiology. In humans, understanding sugar transport has therapeutic importance (e.g., addressing diabetes or limiting access of cancer cells to sugars), and in plants, these transporters are critical for crop yield and pathogen susceptibility.

  15. International Air Transport Policy

    NASA Technical Reports Server (NTRS)

    Butler, C.

    1972-01-01

    The actions of the Civil Aviation Board in providing assistance and advice to the State Department regarding international air transport policy are discussed. The policies and guidelines of the Civil Aviation Board are defined. The relationship with the policies of the Executive Branch of the Government and the interpretations of the Department of Transportation are reported.

  16. Transportation energy conservation fairs

    SciTech Connect

    Not Available

    1981-01-01

    An energy conservation fair sponsored by the Department of Transportation was described. It demonstrated how average drivers can save transportation dollars by changing driving habits at little or no cost. Exhibitors are listed. Methods for disseminating information and recommendations on how to set up such fairs are discussed. (MCW)

  17. Conservation in transportation

    SciTech Connect

    1980-05-30

    A nationwide examination was made of grassroots energy conservation programs related to transportation. Information compiled from civic groups, trade associations, and corporations is included on driver awareness/mass transit; travel; and ride sharing. It is concluded that a willingness by the public to cooperate in transportation energy conservation exists and should be exploited. (LCL)

  18. Trajectory structures and transport

    SciTech Connect

    Vlad, Madalina; Spineanu, Florin

    2004-11-01

    The special problem of transport in two-dimensional divergence-free stochastic velocity fields is studied by developing a statistical approach, the nested subensemble method. The nonlinear process of trapping determined by such fields generates trajectory structures whose statistical characteristics are determined. These structures strongly influence the transport.

  19. Nouvelles approches en theorie du champ moyen dynamique: le cas du pouvoir thermoelectrique et celui de l'effet orbital d'un champ magnetique

    NASA Astrophysics Data System (ADS)

    Arsenault, Louis-Francois

    Les applications reliees a la generation d'energie motivent la recherche de materiaux ayant un fort pouvoir thermoelectrique (S). De plus, S nous renseigne sur certaines proprietes fondamentales des materiaux, comme, par exemple, la transition entre l'etat coherent et incoherent des quasi-particules lorsque la temperature augmente. Empiriquement, la presence de fortes interactions electron-electron peut mener a un pouvoir thermoelectrique geant. Nous avons donc etudie le modele le plus simple qui tient compte de ces fortes interactions, le modele de Hubbard. La theorie du champ moyen dynamique (DMFT) est tout indiquee dans ce cas. Nous nous sommes concentres sur un systeme tridimensionnel (3d) cubique a face centree (fcc), et ce, pour plusieurs raisons. A) Ce type de cristal est tres commun dans la nature. B) La DMFT donne de tres bons resultats en 3d et donc ce choix sert aussi de preuve de principe de la methode. C) Finalement, a cause de la frustration electronique intrinseque au fcc, celui-ci ne presente pas de symetrie particule-trou, ce qui est tres favorable a l'apparition d'une grande valeur de S. Ce travail demontre que lorsque le materiau est un isolant a demi-remplissage a cause des fortes interactions (isolant de Mott), il est possible d'obtenir de grands pouvoirs thermoelectriques en le dopant legerement. C'est un resultat pratique important. Du point de vue methodologique, nous avons montre comment la limite de frequence infinie de S et l'approche dite de Kelvin, qui considere la limite de frequence nulle avant la limite thermodynamique pour S, donnent des estimations fiables de la vraie limite continue (DC) dans les domaines de temperature appropriee. Ces deux approches facilitent grandement les calculs en court-circuit ant la necessite de recourir a de problematiques prolongements analytiques. Nous avons trouve que la methode de calcul a frequence infinie fonctionne bien lorsque les echelles d'energie sont relativement faibles. En d'autres termes

  20. Les effets bénéfiques de l'accompagnement du patient cancéreux: particularités du Maroc

    PubMed Central

    Lkhoyaali, Sihame; Aitelhaj, Meryem; Errihani, Hassan

    2014-01-01

    Au Maroc la majorité des patients âgés cancéreux sont pris en charge par leurs proches l'accompagnement des patients est à l'origine de conséquences émotionnelles psychiques et financières négatives mais en contrepartie il est à l'origine de plusieurs effets bénéfiques à savoir un resserrement des liens familiaux, une surestime du soi et il est la source d'un bien-être affectif et spirituel qui permet de faire face à la maladie. PMID:25722766

  1. Cooperative transport in nanochannels.

    PubMed

    Bauer, Wolfgang R; Nadler, Walter

    2013-07-01

    Channel transport of different species of particles is viewed usually only in terms of competition and selectivity. In this paper we show that transport of one species may be promoted by the presence of another and that both may even mutually cooperate. We investigate a discretized Markovian model of nanochannel transport via in-channel sites, allowing for the simultaneous transport of several different species of particles; interaction between transported particles is included via the condition of single occupancy on a channel site. By numerically solving the model exactly, particularly an analysis of situations of crowding in the channel is possible and we observe three situations: mutual cooperation, promotion of one species at the cost of the other, and mutual competition. The physical situation has a strong nonequilibrium character as Onsager's relations on coupled flows do not hold.

  2. Organic Anion Transporting Polypeptides

    PubMed Central

    Stieger, Bruno; Hagenbuch, Bruno

    2013-01-01

    Organic anion transporting polypeptides or OATPs are central transporters in the disposition of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of endogenous substrates. The critical role of OATPs in drug disposition has spurred research both in academia and in the pharmaceutical industry. Translational aspects with clinical questions are the focus in academia, while the pharmaceutical industry tries to define and understand the role these transporters play in pharmacotherapy. The present overview summarizes our knowledge on the interaction of food constituents with OATPs, and on the OATP transport mechanisms. Further, it gives an update on the available information on the structure-function relationship of the OATPs, and finally, covers the transcriptional and posttranscriptional regulation of OATPs. PMID:24745984

  3. Undulator Transportation Test Results

    SciTech Connect

    Wolf, Zachary; Horton, Nick; Kharakh, David; Levashov, Yurii; Nuhn, Heinz-Dieter; Poling, Ben; Reese, Ed; /SLAC

    2010-11-17

    A test was performed to determine whether transporting and handling the undulators makes any changes to their properties. This note documents the test. No significant changes to the test undulator were observed. After the LCLS undulators are tuned and fiducialized in the Magnetic Measurement Facility (MMF), they must be transported to storage buildings and transported to the tunnel. It has been established that the undulators are sensitive to temperature. We wish to know whether the undulators are also sensitive to the vibrations and shocks of transportation. To study this issue, we performed a test in which an undulator was measured in the MMF, transported to the tunnel, brought back to the MMF, and re-measured. This note documents the test and the results.

  4. [Herbological study of the botanical origin of Chinese crude drugs "Du-hua" and "Qiang-hua" in ancient China].

    PubMed

    Mikage, Masayuki; Ochimori, Akane

    2007-01-01

    The Chinese crude drug Qiang-hua was listed as an alias of Du-hua in Shen-nong-ben-cao-jing, an herbal journal written during the Han Dynasty, China. Du-hua and Qiang-hua are recognized as different herbs in China these days; the main botanical origin of Du-hua is Angelica spp. and that of Qiang-hua is Notopterygium spp., of the family Umbelliferae. To make clear the botanical origins of Du-hua and Qiang-hua in ancient China, the authors made a herbological study. The findings were as follows: the name of Qiang-hua was given to the genuine Du-hua, which is produced in Qiang Province, an ancient province located in northwest China; the botanical origin of Qiang-hua is presumed to be Notopterygium incisum Ting ex H.T. Chang and N. forbesii Boissieu based on both the morphology and habitat written in ancient herbal journals. Both species are prescribed as having the plant origin of Qiang-hua in the present Chinese Pharmacopoeia. Therefore, we concluded that Du-hua and Qiang-hua were essentially the same drug, and were originally derived from the Notopterygium species in ancient China.

  5. Etude des phenomenes dynamiques ultrarapides et des caracteristiques impulsionnelles d'emission terahertz du supraconducteur YBCO

    NASA Astrophysics Data System (ADS)

    Savard, Stephane

    Les premieres etudes d'antennes a base de supraconducteurs a haute temperature critique emettant une impulsion electromagnetique dont le contenu en frequence se situe dans le domaine terahertz remontent a 1996. Une antenne supraconductrice est formee d'un micro-pont d'une couche mince supraconductrice sur lequel un courant continu est applique. Un faisceau laser dans le visible est focalise sur le micro-pont et place le supraconducteur dans un etat hors-equilibre ou des paires sont brisees. Grace a la relaxation des quasiparticules en surplus et eventuellement de la reformation des paires supraconductrices, nous pouvons etudier la nature de la supraconductivite. L'analyse de la cinetique temporelle du champ electromagnetique emis par une telle antenne terahertz supraconductrice s'est averee utile pour decrire qualitativement les caracteristiques de celle-ci en fonction des parametres d'operation tels que le courant applique, la temperature et la puissance d'excitation. La comprehension de l'etat hors-equilibre est la cle pour comprendre le fonctionnement des antennes terahertz supraconductrices a haute temperature critique. Dans le but de comprendre ultimement cet etat hors-equilibre, nous avions besoin d'une methode et d'un modele pour extraire de facon plus systematique les proprietes intrinseques du materiau qui compose l'antenne terahertz a partir des caracteristiques d'emission de celle-ci. Nous avons developpe une procedure pour calibrer le spectrometre dans le domaine temporel en utilisant des antennes terahertz de GaAs bombarde aux protons H+ comme emetteur et detecteur. Une fois le montage calibre, nous y avons insere une antenne emettrice dipolaire de YBa 2Cu3O7-delta . Un modele avec des fonctions exponentielles de montee et de descente du signal est utilise pour lisser le spectre du champ electromagnetique de l'antenne de YBa 2Cu3O7-delta, ce qui nous permet d'extraire les proprietes intrinseques de ce dernier. Pour confirmer la validite du modele

  6. FROST - FReezing Of coated and uncoated duST particles

    NASA Astrophysics Data System (ADS)

    Wex, H.

    2009-04-01

    In April 2008, the measurement campaign FROST (FReezing Of coated and uncoated duST particles) was conducted at the ACCENT (Atmospheric Composition Change - the European NeTwork of excellence) infrastructure site LACIS (Leipzig Aerosol Cloud Interaction Simulator). During the campaign, size selected coated and uncoated Arizona Test Dust (ATD) particles were characterized with respect to shape, chemical composition, hygroscopic growth and activation, and their ability to act as IN (Ice Nuclei). The ATD particles were dispersed by means of a fluidized bed generator. Coatings were applied in different furnaces, operated at different temperatures. The coatings were either succinic acid, sulphuric acid, or ammonium sulphate. A DMA (Differential Mobility Analyzer) was used for selecting particles with a mobility diameter of 300 nm. The following measurements were done: Three AMS (Aerosol Mass Spectrometers, e.g. Schneider et al. (2005) and references therein) were used to determine particle composition. Particles were collected on grids for subsequent TEM (Transmission Electron Micoscropy) analysis. Hygroscopic growth factors were determined by means of a HH-TDMA (High Humidity Tandem Differential Mobility Analyzer) that measured up to relative humidities (RH) of 98% (Hennig et al. (2005)). The critical super-saturations needed for the activation of the investigated particles into cloud droplets were measured with a continuous flow CCNc (Cloud Condensation Nucleus counter) from DMT (Droplet Measurement Technologies, Roberts and Nenes (2005)). The LACIS flow tube was extended to a length of 8 m, so LACIS could be used to examine the immersion freezing behaviour of the coated and uncoated ATD particles. By a bulk analysis and by the AMS measurements, the ATD particles were found to contain water soluble material, however in small quantities. By means of the online AMS measurements, it was possible to distinguish between thin and thick H2SO4 coatings. For the thin coatings

  7. Paralysie du nerf abducens droit révélant une pansinusite

    PubMed Central

    Bouzidi, Adil; Iferkhass, Said; Hansali, Zine El Abidine; Elmallaoui, Mohammed; Laktaoui, Abdelkader

    2015-01-01

    L'association entre la sinusite, en particulier, sphénoïdale et la paralysie oculomotrice a été déjà décrite dans la littérature, mais reste très rare. Nous rapportons un cas d'une patiente âgée de 14 ans sans antécédents pathologiques particuliers consultant pour une une paralysie du VI gauche survenant dans un contexte fébrile. L'examen ophtalmologiquet complété par un bilan radiologique, à révélé une pansunisite du même coté. Les auteures suggèrent que devant toute paralysie oculomotrice, et après avoir éliminé une étiologie tumorale, il faut rechercher à un foyer infectieux locorégional et le bien traite. PMID:26327958

  8. Active Interrogation Observables for Enrichment Determination of DU Shielded HEU Metal Assemblies with Limited Geometrical Information

    SciTech Connect

    Pena, Kirsten E; McConchie, Seth M; Crye, Jason Michael; Mihalczo, John T

    2011-01-01

    Determining the enrichment of highly enriched uranium (HEU) metal assemblies shielded by depleted uranium (DU) proves a unique challenge to currently employed measurement techniques. Efforts to match time-correlated neutron distributions obtained through active interrogation to Monte Carlo simulations of the assemblies have shown promising results, given that the exact geometries of both the HEU metal assemblies and DU shields are known from imaging and fission site mapping. In certain situations, however, it is desirable to obtain enrichment with limited or no geometrical information of the assemblies being measured. This paper explores the possibility that the utilization of observables in the interrogation of assemblies by time-tagged D-T neutrons, including time-correlated distribution of neutrons and gammas using liquid scintillators operating on the fission chain time scale, can lead to enrichment determination without a complete set of geometrical information.

  9. Association between fatigue and autistic symptoms in children with cri du chat syndrome.

    PubMed

    Claro, Anthony; Cornish, Kim; Gruber, Reut

    2011-07-01

    In the current study, the authors examined whether the fatigue level of children diagnosed with cri du chat syndrome was associated with the expression of autistic symptoms. Sixty-nine children with cri du chat syndrome were compared with 47 children with moderate to severe intellectual disabilities who did not differ on intellectual severity. Participants were assessed using the Infant Sleep Questionnaire ( J. M. B. Morrell, 1999 ) for fatigue-level rating and the Childhood Autism Rating Scale ( E. Schopler, R. J. Reichler, & B. R. Renner, 1988 ) for autism-level rating. In support of the authors' hypothesis, results indicated that children who exhibited high levels of fatigue were more likely to express high levels of autistic symptoms. Contrary to the authors' hypothesis, children in the comparison group who exhibited high levels of fatigue conferred the greatest vulnerability to the expression of autistic symptoms. PMID:21740256

  10. Association between fatigue and autistic symptoms in children with cri du chat syndrome.

    PubMed

    Claro, Anthony; Cornish, Kim; Gruber, Reut

    2011-07-01

    In the current study, the authors examined whether the fatigue level of children diagnosed with cri du chat syndrome was associated with the expression of autistic symptoms. Sixty-nine children with cri du chat syndrome were compared with 47 children with moderate to severe intellectual disabilities who did not differ on intellectual severity. Participants were assessed using the Infant Sleep Questionnaire ( J. M. B. Morrell, 1999 ) for fatigue-level rating and the Childhood Autism Rating Scale ( E. Schopler, R. J. Reichler, & B. R. Renner, 1988 ) for autism-level rating. In support of the authors' hypothesis, results indicated that children who exhibited high levels of fatigue were more likely to express high levels of autistic symptoms. Contrary to the authors' hypothesis, children in the comparison group who exhibited high levels of fatigue conferred the greatest vulnerability to the expression of autistic symptoms.

  11. VizieR Online Data Catalog: Cordoba Carte du Ciel-Astrographic Catalog, CCAC (Orellana+, 2010)

    NASA Astrophysics Data System (ADS)

    Orellana, R. B.; de Biasi, M. S.; Bustos Fierro, I. H.; Calderon, J. H.

    2010-07-01

    This is Cordoba Carte du Ciel-Astrographic Catalog (CCAC) constructed from four Carte du Ciel and one Astrographic Catalog photographic plates for first epoch positions in the region of the open cluster Collinder 132. The plates were digitized using the MAMA measuring machine from the Paris Observatory. Stars from Tycho-2 catalogue (Hog et al., 2000, Cat. I/259) were used as reference stars. Every plate was reduced independently from the others adopting a first order polynomial in the measured coordinates. Proper motions were calculated using the CCAC positions as first epoch, and as second epoch the positions given by UCAC2 (Zacharias et al., 2004, Cat. I/289) and USNO-B1.0 (Monet et al., 2003, Cat. I/284). (2 data files).

  12. Du Pont Classification of ASASSN-16jc as a Young SN Ia

    NASA Astrophysics Data System (ADS)

    Shappee, Benjamin J.; Prieto, J. L.; Rich, J.; Seibert, M.; Madore, B.; Poetrodjojo, Henry; D'Agostino, Joshua

    2016-08-01

    We report optical spectroscopy (range 370-910 nm) of ASASSN-16jc discovered by the All-Sky Automated Survey for Supernovae (ASAS-SN; Shappee et al. 2014, ApJ, 788, 48) using the du Pont 2.5-m telescope (+ WFCCD) at Las Campanas Observatory on Aug. 24 2016 UT. We performed a cross-correlation with a library of supernova spectra using the "Supernova Identification" code (SNID; Blondin and Tonry 2007, Ap.J. 666, 1024).

  13. Watershed Data Management (WDM) Database for Salt Creek Streamflow Simulation, DuPage County, Illinois

    USGS Publications Warehouse

    Murphy, Elizabeth A.; Ishii, Audrey

    2006-01-01

    The U.S. Geological Survey (USGS), in cooperation with DuPage County Department of Engineering, Stormwater Management Division, maintains a database of hourly meteorologic and hydrologic data for use in a near real-time streamflow simulation system, which assists in the management and operation of reservoirs and other flood-control structures in the Salt Creek watershed in DuPage County, Illinois. The majority of the precipitation data are collected from a tipping-bucket rain-gage network located in and near DuPage County. The other meteorologic data (wind speed, solar radiation, air temperature, and dewpoint temperature) are collected at Argonne National Laboratory in Argonne, Illinois. Potential evapotranspiration is computed from the meteorologic data. The hydrologic data (discharge and stage) are collected at USGS streamflow-gaging stations in DuPage County. These data are stored in a Watershed Data Management (WDM) database. This report describes a version of the WDM database that was quality-assured and quality-controlled annually to ensure the datasets were complete and accurate. This version of the WDM database contains data from January 1, 1997, through September 30, 2004, and is named SEP04.WDM. This report provides a record of time periods of poor data for each precipitation dataset and describes methods used to estimate the data for the periods when data were missing, flawed, or snowfall-affected. The precipitation dataset data-filling process was changed in 2001, and both processes are described. The other meteorologic and hydrologic datasets in the database are fully described in the annual U.S. Geological Survey Water Data Report for Illinois and, therefore, are described in less detail than the precipitation datasets in this report.

  14. Rainfall in and near Du Page County, Illinois, February 1986-September 1991

    USGS Publications Warehouse

    Duncker, J.J.; Vail, T.J.; Earle, J.D.

    1993-01-01

    Rainfall for 14 rainfall-gaging stations located in and near Du Page County, Illinois, are presented. The rainfall data were collected from February 1986 through September 1991 as part of an on-going cooperative rainfall-runoff investigation. Station descriptions identify the location of and equpiment installed at each rainfall-gaging station. Total daily rainfall is tabulated for each rainfall-gaging staion for each water year. Periods of missing record and snow-affected precipitation totals are identified.

  15. Rainfall in and near Du Page County, Illinois, October 1991-September 1995

    USGS Publications Warehouse

    Straub, T.D.; Hornewer, N.J.; Duncker, J.J.

    1998-01-01

    Twenty-four hour rainfall data are presented for 11 rain gages in and near Du Page County, Illinois. Daily rainfall totals were recorded from October 1, 1991, to September 30, 1995. Station descriptions include site identifiers, locations, drainage basins, types of instrumentation, accuracy, and periods of record. Missing and partial rainfall data, and precipitation totals affected by snowfall have been noted for the periods of record.

  16. Diagnostic du plasma d'ablation laser pour lacroissance de couches minces

    NASA Astrophysics Data System (ADS)

    Basillais, A.; Benzerga, R.; Le Menn, E.; Mathias, J.; Boulmer-Leborgne, C.; Perrière, J.

    2003-06-01

    Dans ce travail, nous nous sommes intéressés à la croissance de films de nitrure d'aluminium par ablation laser d'une cible d'aluminium assistée par un plasma d'azote créé par une décharge RF. Parallèlement, la spectroscopie d'émission a été largement utilisée pour le diagnostic de la plume plasma et du plasma de décharge RF afin de trouver des informations permettant de suivre le phénomène de croissance et qui seraient la signature d'un film de bonne stœchiométrie et qualité cristalline ou son contraire. Ainsi, l'étude de l'émission de la raie d'oxygène à 777nm dans le plasma d'ablation laser a permis d'expliquer le mécanisme de contamination des films par l'oxygène. De la même façon, nous nous sommes intéressés à l'émission de l'azote atomique dans la plume plasma et proche du substrat, dans la zone sombre où ces espèces participent directement à la croissance du film. Ainsi l'étude parallèle de l'influence des paramètres expérimentaux sur la qualité des films et sur la composition du plasma nous a permis d'optimiser le dispositif expérimental.

  17. Cri du chat syndrome and primary ciliary dyskinesia: a common genetic cause on chromosome 5p.

    PubMed

    Shapiro, Adam J; Weck, Karen E; Chao, Kay C; Rosenfeld, Margaret; Nygren, Anders O H; Knowles, Michael R; Leigh, Margaret W; Zariwala, Maimoona A

    2014-10-01

    Cri du chat syndrome (CdCS) and primary ciliary dyskinesia (PCD) are rare diseases that present with frequent respiratory symptoms. PCD can be caused by hemizygous DNAH5 mutation in combination with a 5p segmental deletion attributable to CdCS on the opposite chromosome. Chronic oto-sino-pulmonary symptoms or organ laterality defects in CdCS should prompt an evaluation for PCD. PMID:25066065

  18. Cri du Chat Syndrome and Primary Ciliary Dyskinesia: A Common Genetic Cause on Chromosome 5p

    PubMed Central

    Shapiro, Adam J.; Weck, Karen E.; Chao, Kay C.; Rosenfeld, Margaret; Nygren, Anders O. H.; Knowles, Michael R.; Leigh, Margaret W.; Zariwala, Maimoona A.

    2014-01-01

    Cri du chat syndrome (CdCS) and primary ciliary dyskinesia (PCD) are rare diseases that present with frequent respiratory symptoms. PCD can be caused by hemizygous DNAH5 mutation in combination with a 5p segmental deletion attributable to CdCS on the opposite chromosome. Chronic oto-sino-pulmonary symptoms or organ laterality defects in CdCS should prompt an evaluation for PCD. PMID:25066065

  19. Décompression chirurgicale du syndrome de défilé thoraco-brachial

    PubMed Central

    Lukulunga, Loubet Unyendje; Moussa, Abdou Kadri; Mahfoud, Mustapha; Ismael, Farid; Berrada, Mohamed Saleh; El Yaacoubi, Moradh

    2014-01-01

    Le syndrome de défilé thoraco-brachial est une pathologie souvent méconnue à cause de diagnostic difficile par manque des signes pathognomoniques conduisant souvent à des errances. Les manifestations cliniques dépendent selon qu'il s'agit d'une compression nerveuse, vasculaire ou vasculo-nerveuse. Le but de cette étude est de décrire certains aspects cliniques particuliers et évaluer le résultat fonctionnel après la décompression chirurgicale du paquet vasculo-nerveux. Notre étude rétrospective a porté sur l'analyse des données cliniques, radiologiques, IRM et EMG sur les patients opérés entre janvier 2010 et juillet 2013 du syndrome de défilé thoraco-brachial dans le service de traumatologie orthopédie de l'hôpital Ibn Sina de Rabat. 15 cas ont été colligés: 12 cas post traumatiques (fracture de la clavicule) et 3 cas d'origines congénitales, dont l’âge moyen était 35 ans (20 à 50 ans) avec 9 femmes et 6 hommes. A la fin du traitement, le score de Dash est passé de 109 (46% Normal=0) à 70 (20%), et le stress test de Roos était de 70/100 à 80/100. Le résultat était excellent dans 12 cas soit (80%) et moins bon dans dans 3 cas (20%). En définitive, la résection de malformations osseuses, l'excision des brides et la neurolyse du plexus brachial suivie de la rééducation a donné une bonne évolution fonctionnelle. PMID:25709735

  20. LA TRANSPLANTATION HÉPATIQUE ORTHOTOPIQUE À L’UNIVERSITÉ DU COLORADO

    PubMed Central

    Corman, J.; Starzl, T. E.

    2010-01-01

    Ce travail a été réalisé grâce aux fonds de recherche de la Veterans Administration, aux fonds RR-00051 et RR-00069 du programme des centres de recherche clinique générale de la Division of Research Resources, National Institutes of Health, et aux fonds AI-10176-01, AI-AM-08898, et AM-07772. PMID:21572894

  1. L'effet des deformations plastiques severes sur les proprietes d'hydruration du magnesium

    NASA Astrophysics Data System (ADS)

    Lang, Julien

    Le travail de recherche effectue durant mon projet de maitrise en physique a l'Universite du Quebec a Trois-Rivieres dans les laboratoires de l'Institut de Recherche sur l'Hydrogene etait de comparer l'effet du laminage a froid de la poudre de MgH2 avec celui du broyage mecanique. Nous avons etudie cette nouvelle technique en utilisant un laminoir vertical concu specialement pour laminer de la poudre. Nous avons lamine la poudre de MgH2 5, 25, 50 et 100 fois. La comparaison de la morphologie de la poudre de MgH 2 telle que recu du manufacturier et broye mecaniquement pendant 30 minutes avec celle de la poudre laminee ete faite a l'aide d'un microscope electronique a balayage. Nous avons par la suite mesure les proprietes de sorption d'hydrogene grace un appareil PCT de type Sievert. Nous avons aussi determine la structure cristalline par diffraction de rayons X. A partir de ces resultats, nous avons constate que le nombre optimal de laminages est de cinq et a les caracteristiques d'absorption/desorption d'hydrogene similaires a un broyage mecanique de 30 minutes. Nous avons aussi utilise les courbes de cinetiques d'absorption et de desorption d'hydrogene pour calculer l'etape limitative dans les reactions de sorption des echantillons lamines. Comme cinq laminages se font en environ 10 secondes, on voit que le laminage a froid est une technique plus interessante industriellement que le broyage mecanique a cause de l'important gain en temps et en energie.

  2. Malformations vasculaires au cours du syndrome de Williams-Beuren: à propos de trois nouvelles observations

    PubMed Central

    Sator, Hicham; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Dafiri, Rachida; Chat, Latifa

    2016-01-01

    Le syndrome de Williams-Beuren est une maladie génétique rare, il associe classiquement une dysmorphie faciale assez spécifique, des malformations cardiovasculaires et un profil neuropsychologique particulier. Nous rapportons les observations de trois enfants atteints du syndrome de Williams-Beuren en insistant surtout sur les anomalies vasculaires observées sur l'angio-scanner et angio-IRM. PMID:27200143

  3. Nucleocytoplasmic transport of macromolecules.

    PubMed Central

    Corbett, A H; Silver, P A

    1997-01-01

    Nucleocytoplasmic transport is a complex process that consists of the movement of numerous macromolecules back and forth across the nuclear envelope. All macromolecules that move in and out of the nucleus do so via nuclear pore complexes that form large proteinaceous channels in the nuclear envelope. In addition to nuclear pores, nuclear transport of macromolecules requires a number of soluble factors that are found both in the cytoplasm and in the nucleus. A combination of biochemical, genetic, and cell biological approaches have been used to identify and characterize the various components of the nuclear transport machinery. Recent studies have shown that both import to and export from the nucleus are mediated by signals found within the transport substrates. Several studies have demonstrated that these signals are recognized by soluble factors that target these substrates to the nuclear pore. Once substrates have been directed to the pore, most transport events depend on a cycle of GTP hydrolysis mediated by the small Ras-like GTPase, Ran, as well as other proteins that regulate the guanine nucleotide-bound state of Ran. Many of the essential factors have been identified, and the challenge that remains is to determine the exact mechanism by which transport occurs. This review attempts to present an integrated view of our current understanding of nuclear transport while highlighting the contributions that have been made through studies with genetic organisms such as the budding yeast, Saccharomyces cerevisiae. PMID:9184010

  4. Bile acid transporters

    PubMed Central

    Dawson, Paul A.; Lan, Tian; Rao, Anuradha

    2009-01-01

    In liver and intestine, transporters play a critical role in maintaining the enterohepatic circulation and bile acid homeostasis. Over the past two decades, there has been significant progress toward identifying the individual membrane transporters and unraveling their complex regulation. In the liver, bile acids are efficiently transported across the sinusoidal membrane by the Na+ taurocholate cotransporting polypeptide with assistance by members of the organic anion transporting polypeptide family. The bile acids are then secreted in an ATP-dependent fashion across the canalicular membrane by the bile salt export pump. Following their movement with bile into the lumen of the small intestine, bile acids are almost quantitatively reclaimed in the ileum by the apical sodium-dependent bile acid transporter. The bile acids are shuttled across the enterocyte to the basolateral membrane and effluxed into the portal circulation by the recently indentified heteromeric organic solute transporter, OSTα-OSTβ. In addition to the hepatocyte and enterocyte, subgroups of these bile acid transporters are expressed by the biliary, renal, and colonic epithelium where they contribute to maintaining bile acid homeostasis and play important cytoprotective roles. This article will review our current understanding of the physiological role and regulation of these important carriers. PMID:19498215

  5. SLC4A Transporters

    PubMed Central

    Choi, Inyeong

    2016-01-01

    SLC4A gene family proteins include bicarbonate transporters that move HCO3− across the plasma membrane and regulate intracellular pH and transepithelial movement of acid–base equivalents. These transporters are Cl/HCO3 exchangers, electrogenic Na/HCO3 cotransporters, electroneutral Na/HCO3 cotransporters, and Na+-driven Cl/HCO3 exchanger. Studies of the bicarbonate transporters in vitro and in vivo have demonstrated their physiological importance for acid–base homeostasis at the cellular and systemic levels. Recent advances in structure/function analysis have also provided valuable information on domains or motifs critical for regulation, ion translocation, and protein topology. This chapter focuses on the molecular mechanisms of ion transport along with associated structural aspects from mutagenesis of particular residues and from chimeric constructs. Structure/function studies have helped to understand the mechanism by which ion substrates are moved via the transporters. This chapter also describes some insights into the structure of SLC4A1 (AE1) and SLC4A4 (NBCe1) transporters. Finally, as some SLC4A transporters exist in concert with other proteins in the cells, the structural features associated with protein–protein interactions are briefly discussed. PMID:23177984

  6. Legal Aspects of Pupil Transportation.

    ERIC Educational Resources Information Center

    Mawdsley, Ralph D.

    The legal aspects of pupil transportation are examined, including the liability of various factions for transportation decisions and the duty of school districts to provide adequate transportation. Discussed are court decisions dealing with such complex topics as transportation of special education students, transportation for purpose of…

  7. VIEW OF CRAWLER TRANSPORTER NO. 1 (LEFT) AND CRAWLER TRANSPORTER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF CRAWLER TRANSPORTER NO. 1 (LEFT) AND CRAWLER TRANSPORTER NO. 2 (RIGHT) AT PARKING/MAINTENANCE SITE. - Cape Canaveral Air Force Station, Launch Complex 39, Crawler Transporters, Launcher Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  8. The DuPont Conference: Implications for the Chemical Technology Curriculum

    NASA Astrophysics Data System (ADS)

    Kenkel, John; Rutledge, Sue; Kelter, Paul B.

    1998-05-01

    Southeast Community College (SCC) hosted the first DuPont Conference for Chemical Technology Education at its Lincoln, Nebraska campus October 4-6, 1997. The conference brought together fourteen practicing chemists and chemistry technicians and five college and university faculty members for the express purpose of suggesting new laboratory activities that would help relate the real world of work to the education of chemical laboratory technicians in community colleges. Participants included seven men and seven women from DuPont, Procter & Gamble, Eastman Chemical, Eastman Kodak, Dow Chemical, Air Products and Chemicals, Monsanto, Union Carbide, the Nebraska Agriculture Laboratory, and the University of Nebraska Biological Process Development Facility, Department of Food Science. The conference, sponsored by the E. I. DuPont DeNemours & Company through a grant awarded to SCC in June 1997, was intended to help further the goals of the two major projects underway at SCC, funded by the National Science Foundation's Advanced Technological Education Program. These projects, dubbed "Assignment: Chemical Technology I and II", or ACT-I and ACT-II, are curriculum and materials development projects. The invited scientists had between 2 and 32 years of experience that ranged from bench work to management levels. Many are or have been active on the national scene as members and officers of the American Chemical Society's Division of Chemical Technicians and the ACS Committee on Technician Activities.

  9. Assessment of low-flow water quality in the Du Page River, Illinois

    USGS Publications Warehouse

    Freeman, W.O.; Schmidt, A.R.; Stamer, J.K.

    1986-01-01

    The relations of several stream processes to concentrations of dissolved oxygen and other constituents during low-flow periods were evaluated for a 70.3-mile reach of the Du Page River in northeastern Illinois, using measured data and computer simulations. Reaeration rates and traveltimes were measured at various flow rates using a steady-state gas-tracer technique. Stream discharge, stage, temperature, and chemical constituent concentrations were measured during two 24-hour periods in July and August 1983. These data were used to describe water quality and to calibrate and verify the QUAL-II one dimensional, steady-state, water quality model. Dissolved oxygen concentrations did not meet the State water quality standards in several subreaches of the Du Page River. Concentrations were consistently below the State minimum dissolved oxygen standard in the downstream 8 miles of the East Branch Du Page River. Model simulations indicate that although ammonia oxidation played a role in the dissolved oxygen depletion, the primary factor was sediment oxygen demand. Other measured chemical constituents that did not comply with the State water quality standards in several subreaches of the river included ammonia, iron, fluoride, and total dissolved solids. (USGS)

  10. Cancer du sein sur tissu mammaire ectopique: à propos de 2 cas

    PubMed Central

    Haddad, Houssam; Bourhaleb, Zouhour; El Harroudi, Tijani; Mezouar, Loubna; El Hfid, Mohamed

    2012-01-01

    Le cancer du sein sur tissu mammaire ectopique est une tumeur rare qui représente 0,2 à 0,6% de l′ensemble des cancers du sein. Les auteurs en rapportent 2 cas pris en charge dans 2 centres d′oncologie marocains. Il s′agit de 2 patientes âgées de 31 ans et 47 ans présentant un cancer du sein sur tissu mammaire ectopique en situation axillaire. Une tumorectomie avec curage ganglionnaire axillaire homolatéral a été réalisée chez les 2 patientes dont une après une chimiothérapie néoadjuvante. Le traitement adjuvant a compris une chimiothérapie, radiothérapie puis une hormonothérapie. Après un recul de 12 mois et 20 mois respectivement, les 2 patientes sont en rémission complète. PMID:23330041

  11. Miners, masculinity and the "Bataille du Charbon" in France, 1944-1948.

    PubMed

    Diamond, Hanna

    2011-01-01

    In 1944, the French provisional government, backed by the Parti communiste français and the Confédération générale du travail, undertook an aggressive propaganda campaign to persuade miners to embark upon a 'battle for coal' which raised their efforts in extracting coal to that of a national endeavour. At the same time, miners had great hopes that nationalisation of the coal industry, under discussion at this time, would bring significant improvement to their working lives. In identifying the ways in which publicists posited miners as an ideal of working-class manhood, this article will argue that "la bataille du charbon" marks a crucial moment in the celebration of working-class masculinity and that the "statut des mineurs" which was passed in 1946 as a part of nationalisation enshrined many of the existing gender assumptions about mining life. What does an incorporation of gender to an analysis of the treatment of miners in the years 1944-1948 add to our understandings of the various economic, political and social dynamics around "la bataille du charbon"? How do these insights inform our perceptions of French coalfield societies in the mid-twentieth century?

  12. Inositol transport proteins.

    PubMed

    Schneider, Sabine

    2015-04-28

    The cyclic polyol myo-inositol is a key molecule in many different metabolic pathways among all organisms; in addition, it is fundamental for osmotic balance in the mammalian brain. This review sums up inositol transporters from eukaryotic organisms, elucidating their vital role in regulating the intracellular distribution and uptake of inositol. They can be divided into two groups according to their transport mechanisms: (1) sodium ion coupled inositol transporters that belong to the Solute Carrier Families 5 and 6-like Superfamily and, (2) proton coupled inositol symporters that are members of the Major Facilitator Superfamily. Intriguingly members of both families offer promising targets for medical treatment of a variety of diseases.

  13. Fuels for transportation.

    PubMed

    Fredholm, Bertil B; Nordén, Bengt

    2010-01-01

    There is a need to reduce the amount of fossil energy used for transport, both because of the easily available fossil fuel is becoming sparser and because of climate concerns. In this article, the concept of "peak oil" is briefly presented. Second, a practical approach to reduction of fossil fuel use for transport elaborated by two British commissions is presented. A key feature is the introduction of electric cars. This raises the third issue covered in this article: namely, how battery technology is going to meet the increasing needs posed by the transport sector. PMID:20873684

  14. DUSCOBS - a depleted-uranium silicate backfill for transport, storage, and disposal of spent nuclear fuel

    SciTech Connect

    Forsberg, C.W.; Pope, R.B.; Ashline, R.C.; DeHart, M.D.; Childs, K.W.; Tang, J.S.

    1995-11-30

    A Depleted Uranium Silicate COntainer Backfill System (DUSCOBS) is proposed that would use small, isotopically-depleted uranium silicate glass beads as a backfill material inside storage, transport, and repository waste packages containing spent nuclear fuel (SNF). The uranium silicate glass beads would fill all void space inside the package including the coolant channels inside SNF assemblies. Based on preliminary analysis, the following benefits have been identified. DUSCOBS improves repository waste package performance by three mechanisms. First, it reduces the radionuclide releases from SNF when water enters the waste package by creating a local uranium silicate saturated groundwater environment that suppresses (1) the dissolution and/or transformation of uranium dioxide fuel pellets and, hence, (2) the release of radionuclides incorporated into the SNF pellets. Second, the potential for long-term nuclear criticality is reduced by isotopic exchange of enriched uranium in SNF with the depleted uranium (DU) in the glass. Third, the backfill reduces radiation interactions between SNF and the local environment (package and local geology) and thus reduces generation of hydrogen, acids, and other chemicals that degrade the waste package system. In addition, the DUSCOBS improves the integrity of the package by acting as a packing material and ensures criticality control for the package during SNF storage and transport. Finally, DUSCOBS provides a potential method to dispose of significant quantities of excess DU from uranium enrichment plants at potential economic savings. DUSCOBS is a new concept. Consequently, the concept has not been optimized or demonstrated in laboratory experiments.

  15. EBS Radionuclide Transport Abstraction

    SciTech Connect

    J.D. Schreiber

    2005-08-25

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in ''Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration'' (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment for the license application (TSPA-LA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA-LA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers

  16. Fentes labiopalatines dans la province du Katanga en République Démocratique du Congo: Aspects épidémiologiques, anatomocliniques et thérapeutiques

    PubMed Central

    Sangwa, Cedrick Milindi; Mukuku, Olivier; Tshisuz, Christian; Panda, Jules Mulefu; Kakinga, Mireille; Kitembo, Marius Feruzi; Mutomb, Jean-Felix; Odimba, Bwana Fwamba

    2014-01-01

    Les fentes labiopalatines sont les malformations les plus rencontrées de la sphère orofaciale. L'objectif est de décrire le profil épidémiologique, anatomoclinique et thérapeutique des fentes labiopalatines observées dans la province minière du Katanga au sud-est de la République Démocratique du Congo. Il s'agit d'une étude transversale réalisée dans quatre institutions hospitalières de la province du Katanga dans des districts sanitaires différents (Hôpital Jason Sendwe à Lubumbashi, Hôpital Gécamines Panda à Likasi, Hôpital Gécamines du personnel à Kolwezi, Hôpital General de référence de Kamina) et qui a porté sur 154 cas de fentes labiopalatines enregistrés au cours de la période allant du 1er mai 2010 au 30 septembre 2012. L'âge moyen de consultation était de 11,8 ans et une prédominance masculine (55,2%) était notée. Un pic était noté chez les deux premiers nés de la famille (55,8%). Nous avons enregistré 20,7% des cas de consanguinité dont 54,2% de premier degré. La fréquence des différents types de fentes labiopalatines diminue au fur à mesure que la fente s'étend de la lèvre supérieure au palais en passant par l'alvéole : 72% (labiales), 21,4% (labiopalatines) et 7,7% (palatines). Les variétés unilatérales sont plus fréquentes (76,7%) que les bilatérales (16,1%). Dans les formes unilatérales, le côté gauche est plus concerné (47,1%) par rapport au côté droit (38,6%). L'évaluation de la gravité selon Anastassov montre que 50,6% de nos patients étaient de degré moyen et 16,2% étaient à un degré sévère. Les malformations associées ont été retrouvées dans 5% des cas et elles sont à prédominance squelettique. C'est la technique de Millard qui a été la plus pratiquée (72/130). Les résultats étaient excellents dans 71,5% contre 1,5% de mauvais. Le séjour d'hospitalisation était de 3 jours et le taux de complications post opératoire était de 2,98%. PMID:25328615

  17. Évolution nycthémérale des composantes biochimiques du phytoplancton de la retenue du barrage Idriss premier (Fès, Maroc)

    NASA Astrophysics Data System (ADS)

    Bahhou, J.; Alaoui Mhamdi, M.

    1999-03-01

    The diel changes of the biochemical composition of the phytoplankton were studied in the Idriss first reservoir (located on the Inaouen river at thirty Km from the city of Fes, Morrocco) during September 1994. Several biomass and metabolic indicators (proteins, carbohydrates, lipids, chlorophyll a and primary production) were assessed every fourth hour over tow days (7, 8 and 9 September). Since the Protein/Carbohydrates ratio (P/C) is largely recognised as a good integrator of the metabolic functions of the cells, we examined its distribution pattern concomitantly with aforementioned parameters. The results demonstrated enhanced P/C ratios clearly indicating that nutrients were sufficiently available for growth. In addition, this index showed a diel significant variation with levels higher in the night than in the day. Moreover, these results suggest that phytoplankton species during the night used the day-synthesised carbohydrates to insure the cell metabolic functioning. The P/C presents relatively high values in proposition to the ones that have been recorded in temperate regions, and seems to be related to azotic inputs of the Inaouen river. Dans le but de parfaire nos connaissances sur le fonctionnement du sous écosystème phytoplancton, nous nous sommes intéressés à étudier son cycle nycthéméral et son métabolisme cellulaire dans la retenue du barrage Idriss premier. Cette dernière, construite sur l'Oued Inaouène, est située à une trentaine de Km de la ville de Fès. Au cours de ce cycle, les prélèvements ont été effectués selon une séquence temporelle de 4 heures pendant 48 heures, les 7, 8 et 9 septembre 1994. L'étude de l'évolution des composantes biochimiques des cellules phytoplanctoniques à savoir les protéines, les glucides et les lipides a permis de mettre en évidence des variations nycthémérales importantes. Ces variations sont d'autant plus importantes que les variations spatiales observées entre les profondeurs. De plus

  18. Accident resistant transport container

    DOEpatents

    Anderson, J.A.; Cole, K.K.

    The invention relates to a container for the safe air transport of plutonium having several intermediate wood layers and a load spreader intermediate an inner container and an outer shell for mitigation of shock during a hypothetical accident.

  19. Accident resistant transport container

    DOEpatents

    Andersen, John A.; Cole, James K.

    1980-01-01

    The invention relates to a container for the safe air transport of plutonium having several intermediate wood layers and a load spreader intermediate an inner container and an outer shell for mitigation of shock during a hypothetical accident.

  20. Crew Transportation Operations Standards

    NASA Technical Reports Server (NTRS)

    Mango, Edward J.; Pearson, Don J. (Compiler)

    2013-01-01

    The Crew Transportation Operations Standards contains descriptions of ground and flight operations processes and specifications and the criteria which will be used to evaluate the acceptability of Commercial Providers' proposed processes and specifications.

  1. Rotorcraft air transportation

    NASA Technical Reports Server (NTRS)

    Gilbert, G. A.

    1983-01-01

    Intermodal relationships and the particular ways in which they affect public transportation applications of rotorcraft are addressed. Some aspects of integrated services and general comparisons with other transportation modes are reviewed. Two potential application scenarios are discussed: down-to-downtown rotorcraft service and urban public transport rotorcraft service. It is concluded that to integrate well with ground access modes community rotorcraft service should be limited stop service with published schedules, and operate on a few specific routes between a few specific destinations. For downtown-to-downtown service, time savings favorable to rotorcraft are benefits that reflect its more direct access, relatively higher line-haul travel speeds, and less circuitous travel. For the scenario of public transport within urban areas, first, improving cruise speeds has a limited potential due to allowing for a ""station spacing'' effect. Secondly, public acceptance of higher acceleration/deceleration rates may be just as effective as a technological innovation as achieving higher cruise speeds.

  2. Biofuel Ethanol Transport Risk

    EPA Science Inventory

    Ethanol production has increased rapidly over the last 10 years and many communities lack awareness of the increased and growing extent of biofuel transportation through their jurisdictions. These communities and their emergency responders may not have the information and resour...

  3. Transportation Baseline Report

    SciTech Connect

    Fawcett, Ricky Lee; Kramer, George Leroy Jr.

    1999-12-01

    The National Transportation Program 1999 Transportation Baseline Report presents data that form a baseline to enable analysis and planning for future Department of Energy (DOE) Environmental Management (EM) waste and materials transportation. In addition, this Report provides a summary overview of DOE’s projected quantities of waste and materials for transportation. Data presented in this report were gathered as a part of the IPABS Spring 1999 update of the EM Corporate Database and are current as of July 30, 1999. These data were input and compiled using the Analysis and Visualization System (AVS) which is used to update all stream-level components of the EM Corporate Database, as well as TSD System and programmatic risk (disposition barrier) information. Project (PBS) and site-level IPABS data are being collected through the Interim Data Management System (IDMS). The data are presented in appendices to this report.

  4. Air transportation energy efficiency

    NASA Technical Reports Server (NTRS)

    Williams, L. J.

    1977-01-01

    The energy efficiency of air transportation, results of the recently completed RECAT studies on improvement alternatives, and the NASA Aircraft Energy Efficiency Research Program to develop the technology for significant improvements in future aircraft were reviewed.

  5. Animal transportation networks.

    PubMed

    Perna, Andrea; Latty, Tanya

    2014-11-01

    Many group-living animals construct transportation networks of trails, galleries and burrows by modifying the environment to facilitate faster, safer or more efficient movement. Animal transportation networks can have direct influences on the fitness of individuals, whereas the shape and structure of transportation networks can influence community dynamics by facilitating contacts between different individuals and species. In this review, we discuss three key areas in the study of animal transportation networks: the topological properties of networks, network morphogenesis and growth, and the behaviour of network users. We present a brief primer on elements of network theory, and then discuss the different ways in which animal groups deal with the fundamental trade-off between the competing network properties of travel efficiency, robustness and infrastructure cost. We consider how the behaviour of network users can impact network efficiency, and call for studies that integrate both network topology and user behaviour. We finish with a prospectus for future research.

  6. Commercial jet transport crashworthiness

    NASA Technical Reports Server (NTRS)

    Widmayer, E.; Brende, O. B.

    1982-01-01

    The results of a study to identify areas of research and approaches that may result in improved occupant survivability and crashworthiness of transport aircraft are given. The study defines areas of structural crashworthiness for transport aircraft which might form the basis for a research program. A 10-year research and development program to improve the structural impact resistance of general aviation and commercial jet transport aircraft is planned. As part of this program parallel studies were conducted to review the accident experience of commercial transport aircraft, assess the accident performance of structural components and the status of impact resistance technology, and recommend areas of research and development for that 10-year plan. The results of that study are also given.

  7. Transportation Network Topologies

    NASA Technical Reports Server (NTRS)

    Alexandrov, Natalia (Editor)

    2004-01-01

    The existing U.S. hub-and-spoke air transportation system is reaching saturation. Major aspects of the current system, such as capacity, safety, mobility, customer satisfaction, security, communications, and ecological effects, require improvements. The changing dynamics - increased presence of general aviation, unmanned autonomous vehicles, military aircraft in civil airspace as part of homeland defense - contributes to growing complexity of airspace. The system has proven remarkably resistant to change. NASA Langley Research Center and the National Institute of Aerospace conducted a workshop on Transportation Network Topologies on 9-10 December 2003 in Williamsburg, Virginia. The workshop aimed to examine the feasibility of traditional methods for complex system analysis and design as well as potential novel alternatives in application to transportation systems, identify state-of-the-art models and methods, conduct gap analysis, and thus to lay a foundation for establishing a focused research program in complex systems applied to air transportation.

  8. Animal transportation networks

    PubMed Central

    Perna, Andrea; Latty, Tanya

    2014-01-01

    Many group-living animals construct transportation networks of trails, galleries and burrows by modifying the environment to facilitate faster, safer or more efficient movement. Animal transportation networks can have direct influences on the fitness of individuals, whereas the shape and structure of transportation networks can influence community dynamics by facilitating contacts between different individuals and species. In this review, we discuss three key areas in the study of animal transportation networks: the topological properties of networks, network morphogenesis and growth, and the behaviour of network users. We present a brief primer on elements of network theory, and then discuss the different ways in which animal groups deal with the fundamental trade-off between the competing network properties of travel efficiency, robustness and infrastructure cost. We consider how the behaviour of network users can impact network efficiency, and call for studies that integrate both network topology and user behaviour. We finish with a prospectus for future research. PMID:25165598

  9. Transportation Security Administration

    MedlinePlus

    ... content Official website of the Department of Homeland Security Transportation Security Administration A - Z Index What Can I Bring? Search form Apples Main menu Administrator Travel Security Screening Special Procedures TSA Pre✓® Passenger Support Travel ...

  10. Transportation Network Topologies

    NASA Technical Reports Server (NTRS)

    Holmes, Bruce J.; Scott, John M.

    2004-01-01

    A discomforting reality has materialized on the transportation scene: our existing air and ground infrastructures will not scale to meet our nation's 21st century demands and expectations for mobility, commerce, safety, and security. The consequence of inaction is diminished quality of life and economic opportunity in the 21st century. Clearly, new thinking is required for transportation that can scale to meet to the realities of a networked, knowledge-based economy in which the value of time is a new coin of the realm. This paper proposes a framework, or topology, for thinking about the problem of scalability of the system of networks that comprise the aviation system. This framework highlights the role of integrated communication-navigation-surveillance systems in enabling scalability of future air transportation networks. Scalability, in this vein, is a goal of the recently formed Joint Planning and Development Office for the Next Generation Air Transportation System. New foundations for 21PstP thinking about air transportation are underpinned by several technological developments in the traditional aircraft disciplines as well as in communication, navigation, surveillance and information systems. Complexity science and modern network theory give rise to one of the technological developments of importance. Scale-free (i.e., scalable) networks represent a promising concept space for modeling airspace system architectures, and for assessing network performance in terms of scalability, efficiency, robustness, resilience, and other metrics. The paper offers an air transportation system topology as framework for transportation system innovation. Successful outcomes of innovation in air transportation could lay the foundations for new paradigms for aircraft and their operating capabilities, air transportation system architectures, and airspace architectures and procedural concepts. The topology proposed considers air transportation as a system of networks, within

  11. Transportation Network Topologies

    NASA Technical Reports Server (NTRS)

    Holmes, Bruce J.; Scott, John

    2004-01-01

    A discomforting reality has materialized on the transportation scene: our existing air and ground infrastructures will not scale to meet our nation's 21st century demands and expectations for mobility, commerce, safety, and security. The consequence of inaction is diminished quality of life and economic opportunity in the 21st century. Clearly, new thinking is required for transportation that can scale to meet to the realities of a networked, knowledge-based economy in which the value of time is a new coin of the realm. This paper proposes a framework, or topology, for thinking about the problem of scalability of the system of networks that comprise the aviation system. This framework highlights the role of integrated communication-navigation-surveillance systems in enabling scalability of future air transportation networks. Scalability, in this vein, is a goal of the recently formed Joint Planning and Development Office for the Next Generation Air Transportation System. New foundations for 21st thinking about air transportation are underpinned by several technological developments in the traditional aircraft disciplines as well as in communication, navigation, surveillance and information systems. Complexity science and modern network theory give rise to one of the technological developments of importance. Scale-free (i.e., scalable) networks represent a promising concept space for modeling airspace system architectures, and for assessing network performance in terms of scalability, efficiency, robustness, resilience, and other metrics. The paper offers an air transportation system topology as framework for transportation system innovation. Successful outcomes of innovation in air transportation could lay the foundations for new paradigms for aircraft and their operating capabilities, air transportation system architectures, and airspace architectures and procedural concepts. The topology proposed considers air transportation as a system of networks, within which

  12. Fluid transport container

    DOEpatents

    DeRoos, Bradley G.; Downing, Jr., John P.; Neal, Michael P.

    1995-01-01

    An improved fluid container for the transport, collection, and dispensing of a sample fluid that maintains the fluid integrity relative to the conditions of the location at which it is taken. More specifically, the invention is a fluid sample transport container that utilizes a fitment for both penetrating and sealing a storage container under controlled conditions. Additionally, the invention allows for the periodic withdrawal of portions of the sample fluid without contamination or intermixing from the environment surrounding the sample container.

  13. Fluid transport container

    DOEpatents

    DeRoos, B.G.; Downing, J.P. Jr.; Neal, M.P.

    1995-11-14

    An improved fluid container for the transport, collection, and dispensing of a sample fluid that maintains the fluid integrity relative to the conditions of the location at which it is taken. More specifically, the invention is a fluid sample transport container that utilizes a fitting for both penetrating and sealing a storage container under controlled conditions. Additionally, the invention allows for the periodic withdrawal of portions of the sample fluid without contamination or intermixing from the environment surrounding the sample container. 13 figs.

  14. Tape transport mechanism

    DOEpatents

    Groh, Edward F.; McDowell, William; Modjeski, Norbert S.; Keefe, Donald J.; Groer, Peter

    1979-01-01

    A device is provided for transporting, in a stepwise manner, tape between a feed reel and takeup reel. An indexer moves across the normal path of the tape displacing it while the tape on the takeup reel side of the indexer is braked. After displacement, the takeup reel takes up the displaced tape while the tape on the feed reel side of the indexer is braked, providing stepwise tape transport in precise intervals determined by the amount of displacement caused by the indexer.

  15. [Recommendations for neonatal transport].

    PubMed

    Moreno Hernando, J; Thió Lluch, M; Salguero García, E; Rite Gracia, S; Fernández Lorenzo, J R; Echaniz Urcelay, I; Botet Mussons, F; Herranz Carrillo, G; Sánchez Luna, M

    2013-08-01

    During pregnancy, it is not always possible to identify maternal or foetal risk factors. Infants requiring specialised medical care are not always born in centres providing intensive care and will need to be transferred to a referral centre where intensive care can be provided. Therefore Neonatal Transport needs to be considered as part of the organisation of perinatal health care. The aim of Neonatal Transport is to transfer a newborn infant requiring intensive care to a centre where specialised resources and experience can be provided for the appropriate assessment and continuing treatment of a sick newborn infant. Intrauterine transfer is the ideal mode of transport when the birth of an infant with risk factors is diagnosed. Unfortunately, not all problems can be detected in advance with enough time to safely transfer a pregnant woman. Around 30- 50% of risk factors will be diagnosed during labour or soon after birth. Therefore, it is important to have the knowledge and resources to resuscitate and stabilise a newborn infant, as well as a specialised neonatal transport system. With this specialised transport it is possible to transfer newly born infants with the same level of care that they would receive if they had been born in a referral hospital, without increasing their risks or affecting the wellbeing of the newborn. The Standards Committee of the Spanish Society of Neonatology reviewed and updated recommendations for intrauterine transport and indications for neonatal transfer. They also reviewed organisational and logistic factors involved with performing neonatal transport. The Committee review included the type of personnel who should be involved; communication between referral and receiving hospitals; documentation; mode of transport; equipment to stabilise newly born infants; management during transfer, and admission at the referral hospital.

  16. Membrane Transport Phenomena (MTP)

    NASA Technical Reports Server (NTRS)

    Mason, Larry W.

    1997-01-01

    The third semi-annual period of the MTP project has been involved with performing experiments using the Membrane Transport Apparatus (MTA), development of analysis techniques for the experiment results, analytical modeling of the osmotic transport phenomena, and completion of a DC-9 microgravity flight to test candidate fluid cell geometries. Preparations were also made for the MTP Science Concept Review (SCR), held on 13 June 1997 at Lockheed Martin Astronautics in Denver. These activities are detailed in the report.

  17. Modelisation et simulation du comportement des alliages de magnesium lors de la deformation a chaud

    NASA Astrophysics Data System (ADS)

    Levesque, Julie

    Les alliages de magnesium sont de plus en plus utilises dans l'industrie automobile. Leur faible masse volumique permet d'alleger les vehicules, donc de diminuer l'utilisation de carburant et les emissions de gaz a effet de serre. La ductilite du magnesium a temperature ambiante est faible, mais une augmentation de celle-ci permet l'activation de systemes de glissement supplementaires et une meilleure formabilite. L'hydroformage a chaud pourrait donc permettre de fabriquer des pieces en alliages de magnesium destinees a l'industrie automobile. L'objectif de ce travail etait de developper un modele numerique permettant de simuler le comportement des alliages de magnesium deformes a temperature moderee (200°C). Les principales difficultes resident dans le fait que le magnesium ne se deforme pas seulement par glissement, mais aussi par maclage. En plus de reorienter les mailles cristallines, le maclage amene egalement un schema de durcissement complexe. Le modele utilise en est un de plasticite cristalline, qui tient compte de l'evolution de la texture lors de la deformation. Le modele de depart a ete adapte au magnesium en y incluant le maclage. Il tient compte de la reorientation des mailles cristallines, ainsi que du durcissement cause par les joints de macles. Le modele a d'abord ete calibre grace aux courbes de traction et de compression uniaxiale, puis a ete valide par la simulation de l'essai de deformation circonferentielle. L'evolution de texture observee a aussi permis de valider le modele. Des equations permettant d'ajuster les parametres du modele en fonction du taux de deformation ont egalement ete developpees. Les diagrammes des limites de formage dans les directions conventionnelle et d'hydroformage ont ete traces. Le maclage semble contribuer legerement a la formabilite des alliages de magnesium a la temperature etudiee. Une augmentation de l'index de sensibilite a la vitesse de deformation a aussi un effet positif sur la formabilite. Les resultats

  18. Regional rainfall-runoff relations for simulation of streamflow for watersheds in Du Page County, Illinois

    USGS Publications Warehouse

    Duncker, James J.; Melching, Charles S.

    1998-01-01

    Rainfall and streamflow data collected from July 1986 through September 1993 were utilized to calibrate and verify a continuous-simulation rainfall-runoff model for three watersheds (11.8--18.0 square miles in area) in Du Page County. Classification of land cover into three categories of pervious (grassland, forest/wetland, and agricultural land) and one category of impervious subareas was sufficient to accurately simulate the rainfall-runoff relations for the three watersheds. Regional parameter sets were obtained by calibrating jointly all parameters except fraction of ground-water inflow that goes to inactive ground water (DEEPFR), interflow recession constant (IRC), and infiltration (INFILT) for runoff from all three watersheds. DEEPFR and IRC varied among the watersheds because of physical differences among the watersheds. Two values of INFILT were obtained: one representing the rainfall-runoff process on the silty and clayey soils on the uplands and lake plains that characterize Sawmill Creek, St. Joseph Creek, and eastern Du Page County; and one representing the rainfall-runoff process on the silty soils on uplands that characterize Kress Creek and parts of western Du Page County. Regional rainfall-runoff relations, defined through joint calibration of the rainfall-runoff model and verified for independent periods, presented in this report, allow estimation of runoff for watersheds in Du Page County with an error in the total water balance less than 4.0 percent; an average absolute error in the annual-flow estimates of 17.1 percent with the error rarely exceeding 25 percent for annual flows; and correlation coefficients and coefficients of model-fit efficiency for monthly flows of at least 87 and 76 percent, respectively. Close reproduction of the runoff-volume duration curves was obtained. A frequency analysis of storm-runoff volume indicates a tendency of the model to undersimulate large storms, which may result from underestimation of the amount of

  19. Facteurs de risque cardiovasculaires au cours du lupus systémique

    PubMed Central

    Harzallah, Amel; Hajji, Mariem; Kaaroud, Hayet; Hamida, Fethi Ben; Abdallah, Taieb Ben

    2015-01-01

    Cette étude a pour objectif d’évaluer la fréquence des facteurs de risque cardiovasculaires au cours du lupus et de préciser leur prévalence. Etude rétrospective portant sur 250 patients ayant un lupus, diagnostiqué selon les critères de l'ACR, hospitalisés entre 1970 et 2013. Les données cliniques et para cliniques ont été recueillies à partir des observations médicales. Il s'agit de 228 femmes et 22 hommes d’âge moyen au diagnostic du lupus de 30, 32 ans (extrêmes: 16-69). La durée moyenne du suivi des patients était de 64 mois (extrêmes: 7 jours- 382mois). Quatre vingt dix patients (36%) étaient hypertendus, 74% avaient une hypercholestérolémie et 22% étaient diabétiques. Pour les autres facteurs de risque cardiovasculaire traditionnels, un âge > 50 ans a été retrouvé dans 40% des cas, le sexe masculin dans 8% des cas, l'obésité dans 76% des cas et le tabagisme dans 11% des cas. Les facteurs de risque surajoutés sont représentés par la présence des anticorps antiphospholipides (47% des cas), la néphropathie lupique (49% des cas), l'insuffisance rénale (42% des cas), la corticothérapie au long cours (74% des cas) et la chronicité de la maladie dans 35% des cas. Les complications cardiovasculaires retrouvées dans notre série étaient: les accidents vasculaires cérébraux (2%) et l'insuffisance coronarienne (5,6%). Devant l'importance du risque cardiovasculaire au cours du lupus, une surveillance rapprochée des facteurs de risque cardio-vasculaires semble primordiale chez les lupiques. PMID:27022427

  20. Transporting Forensic Psychiatric Patients.

    PubMed

    Dike, Charles C; Nicholson, Elizabeth; Young, John L

    2015-12-01

    Patients in a forensic psychiatric facility often require escorted transport to medical facilities for investigations or treatments of physical health ailments. Transporting these patients presents significant safety and custody challenges because of the nature of patients housed in forensic psychiatric facilities. A significant proportion of these patients may be transfers from the Department of Corrections (DOC) under legal mandates for psychiatric evaluation and treatment better provided in a hospital setting, and most of them will return to the DOC. Although departments of correction have protocols for escorting these potentially dangerous individuals, it is unclear whether receiving psychiatric hospitals have established procedures for maintaining the safety of others and custody of these individuals during transportation outside the hospital facility. The literature is sparse on precautions to be observed when transporting dangerous forensic psychiatric patients, including those with high escape risk. In this article, we describe one forensic inpatient facility's procedure for determining the appropriate level needed to transport these individuals outside of the forensic facility. We also describe the risk assessment procedure for determining level of transport. These are quality improvement measures resulting from a critical review of an incident of escape from the forensic facility several years ago.

  1. Organellar Channels and Transporters

    PubMed Central

    Xu, Haoxing; Martinoia, Enrico; Szabo, Ildiko

    2015-01-01

    Decades of intensive research has led to the discovery of most plasma membrane ion channels and transporters and the characterization of their physiological functions. In contrast, although over 80% of transport processes occur inside the cells, the ion flux mechanisms across intracellular membranes (the endoplasmic reticulum, Golgi apparatus, endosomes, lysosomes, mitochondria, chloroplasts, and vacuoles) are difficult to investigate and remain poorly understood. Recent technical advances in super-resolution microscopy, organellar electrophysiology, organelle-targeted fluorescence imaging, and organelle proteomics have pushed a large step forward in the research of intracellular ion transport. Many new organellar channels are molecularly identified and electrophysiologically characterized. Additionally, molecular identification of many of these ion channels/transporters has made it possible to study their physiological functions by genetic and pharmacological means. For example, organellar channels have been shown to regulate important cellular processes such as programmed cell death and photosynthesis, and are involved in many different pathologies. This Special Issue (SI) on Organellar Channels and Transporters aims to provide a forum to discuss the recent advances and to define the standard and open questions in this exciting and rapidly-developing field. Along this line, a new Gordon Research Conference dedicated to the multidisciplinary study of intracellular membrane transport proteins will be launched this coming summer. PMID:25795199

  2. Ion transport in pigmentation

    PubMed Central

    Bellono, Nicholas W.; Oancea, Elena V.

    2014-01-01

    Skin melanocytes and ocular pigment cells contain specialized organelles called melanosomes, which are responsible for the synthesis of melanin, the major pigment in mammals. Defects in the complex mechanisms involved in melanin synthesis and regulation result in vision and pigmentation deficits, impaired development of the visual system,, and increased susceptibility to skin and eye cancers. Ion transport across cellular membranes is critical for many biological processes, including pigmentation, but the molecular mechanisms by which it regulates melanin synthesis, storage, and transfer are not understood. In this review we first discuss ion channels and transporters that function at the plasma membrane of melanocytes; in the second part we consider ion transport across the membrane of intracellular organelles, with emphasis on melanosomes. We discuss recently characterized lysosomal and endosomal ion channels and transporters associated with pigmentation phenotypes. We then review the evidence for melanosomal channels and transporters critical for pigmentation, discussing potential molecular mechanisms mediating their function. The studies investigating ion transport in pigmentation physiology open new avenues for future research and could reveal novel molecular mechanisms underlying melanogenesis. PMID:25034214

  3. Moss hair water transport

    NASA Astrophysics Data System (ADS)

    Pan, Zhao; Wu, Nan; Hurd, Randy; Thomson, Scott; Pitt, William; Truscott, Tadd

    2013-11-01

    We present an investigation of water transportation on a moss (Syntrichia caninervis) indigenous to temperate deserts. The moss typically appears to be in a dry, brown state, but is rehydrated by water during the wet season, making the desert green. Small hairs (500-2000 μm in length, and 40 μm in diameter, d) growing out from the tip of the moss leaves transport water back to the leaves. Through high speed observations and mathematical modeling it appears that this transportation is driven by two different mechanisms. 1) Droplet transport is achieved in three ways: i) A large (10d) droplet attached between two intersecting fibers will move toward the bases of the leaves by the changing angle between the two hairs. ii) The shape of the moss hair is conical, thicker at the base, producing a gradient that moves fluid (5d) toward the leaf similar to cactus spines. iii) We also observe that in some cases a Plateau-Rayleigh instability trigger a series of droplets moving toward the base. 2) Micro-grooves on the moss hair transport a film of water along the moss hair when larger droplets are not available. These various water transportation strategies combine to help the moss to survive in the desert and provide valuable insight.

  4. Transporting Forensic Psychiatric Patients.

    PubMed

    Dike, Charles C; Nicholson, Elizabeth; Young, John L

    2015-12-01

    Patients in a forensic psychiatric facility often require escorted transport to medical facilities for investigations or treatments of physical health ailments. Transporting these patients presents significant safety and custody challenges because of the nature of patients housed in forensic psychiatric facilities. A significant proportion of these patients may be transfers from the Department of Corrections (DOC) under legal mandates for psychiatric evaluation and treatment better provided in a hospital setting, and most of them will return to the DOC. Although departments of correction have protocols for escorting these potentially dangerous individuals, it is unclear whether receiving psychiatric hospitals have established procedures for maintaining the safety of others and custody of these individuals during transportation outside the hospital facility. The literature is sparse on precautions to be observed when transporting dangerous forensic psychiatric patients, including those with high escape risk. In this article, we describe one forensic inpatient facility's procedure for determining the appropriate level needed to transport these individuals outside of the forensic facility. We also describe the risk assessment procedure for determining level of transport. These are quality improvement measures resulting from a critical review of an incident of escape from the forensic facility several years ago. PMID:26668224

  5. Ion transport in pigmentation.

    PubMed

    Bellono, Nicholas W; Oancea, Elena V

    2014-12-01

    Skin melanocytes and ocular pigment cells contain specialized organelles called melanosomes, which are responsible for the synthesis of melanin, the major pigment in mammals. Defects in the complex mechanisms involved in melanin synthesis and regulation result in vision and pigmentation deficits, impaired development of the visual system, and increased susceptibility to skin and eye cancers. Ion transport across cellular membranes is critical for many biological processes, including pigmentation, but the molecular mechanisms by which it regulates melanin synthesis, storage, and transfer are not understood. In this review we first discuss ion channels and transporters that function at the plasma membrane of melanocytes; in the second part we consider ion transport across the membrane of intracellular organelles, with emphasis on melanosomes. We discuss recently characterized lysosomal and endosomal ion channels and transporters associated with pigmentation phenotypes. We then review the evidence for melanosomal channels and transporters critical for pigmentation, discussing potential molecular mechanisms mediating their function. The studies investigating ion transport in pigmentation physiology open new avenues for future research and could reveal novel molecular mechanisms underlying melanogenesis.

  6. L'Abondance du Deutérium, de l'Ultraviolet au Visible

    NASA Astrophysics Data System (ADS)

    Hébrard, Guillaume

    2000-12-01

    Dans le cadre du modèle standard du Big Bang, le deutérium est l'élément dont l'abondance primordiale est la plus sensible à la densité baryonique de l'Univers. Cet élément est uniquement créé lors de la nucléosynthèse primordiale, quelques minutes après le Big Bang ; aucune théorie standard n'en prédit actuellement d'autres sources significatives. Au contraire, étant brûlé dans les étoiles, son abondance D/H décroît au cours de l'évolution cosmique. Les mesures de D/H apportent ainsi des contraintes sur les modèles de Big Bang et d'évolution chimique des galaxies. On peut distinguer trois types de mesures de D/H: les abondances primordiale, proto-solaire et interstellaire, respectivement représentatives de l'Univers il y a environ 15 milliards d'années, 4.5 milliards d'années et à l'époque actuelle. Si l'évolution du deutérium semble qualitativement claire, les résultats concernant ces trois types d'abondance ne convergent pas pour l'instant vers trois valeurs bien définies. Les travaux entrepris durant cette thèse sont reliés à la mesure de l'abondance interstellaire du deutérium. Celle-ci s'obtient habituellement par l'observation spectroscopique en absorption des séries de Lyman de l'hydrogène et du deutérium. Ces observations se font dans le domaine ultraviolet, au moyen d'observatoires spatiaux. Les résultats présentés ici ont été obtenus avec le Télescope spatial Hubble puis le satellite FUSE, récemment mis en orbite. D'autre part, une nouvelle méthode d'observation du deutérium a été proposée, dans le domaine visible à partir de télescopes au sol. Ce travail a mené aux premières détections et à l'identification de la série de Balmer du deutérium, observée en émission dans des régions HII avec le Télescope Canada-France-Hawaii et le Very Large Telescope. On-line Thesis, Guillaume Hébrard

  7. Cultural Heritage Documentation and Integrated Geomatics Techniques in AN Educational Context: Case Bois-Du (belgium)

    NASA Astrophysics Data System (ADS)

    Stal, C.; Goossens, R.; Carlier, L.; Debie, J.; Haoudy, K.; Nuttens, T.; De Wulf, A.

    2013-07-01

    The Walloon Region in Belgium played a leading role in the world economy and in the industrial sciences and engineering since the 19th century. Several relicts, such as important industrial buildings or sites, are spread over a large area and are still dominating the current landscape. Some of these remnants are preserved as monuments, representing the industrial, cultural and ecological transition of the region during the last two centuries. Since 2012, UNESCO recognized the importance of four of the best preserved 19th and 20th century coal mining sites and classified them as World Heritage ("Major Mining Sites of Wallonia", Le Grand-Hornu, Bois-du- Luc, Le Bois du Cazier and Blegny Mine). The four recognised mining sites together form a strip of about 170 km long, containing important examples of the so-called 'neo classical architecture' from the early periods of the industrial era in continental Europe. Motivated by this recognition and by the huge touristic and educational potential of the sites, a partnership between the Walloon government and Ghent University was organized. In this first stage, the collaboration focuses on the site of Bois-du-Luc in the municipality of La Louvière, containing a large series of dwellings, several equipments built between 1853 and 1923 by the Société des Charbonnages du Bois-du-Luc, workshops and heaps. Consisting of numerous buildings dating back to the period between 1838 and 1923, this site is one of Europe's oldest collieries. The collaboration between the Walloon government and Ghent University - Department of Geography fits in the hands-on training which students in land surveying and geomatics receive during their Bachelor studies. For the students it is very interesting that their practical exercises are not limited to the university campus, but that they are involved in a real measurement campaign. The project consists of a series of intensive land surveying campaigns, resulting in highly detailed and accurate

  8. Transport of rimsulfuron and its metabolites in soil columns

    PubMed

    Martins; Mermoud

    1999-02-01

    This paper presents a study on degradation, sorption and transport of the sulfonylurea herbicide rimsulfuron and its major metabolites in alluvial soil columns. The formulation of rimsulfuron was found to strongly affect its degradability. Hydrolysis of pure rimsulfuron takes place rapidly in distilled water (t(1/2)=2.2 days) or indeed instantaneously in alkaline solution. The formulated rimsulfuron (Titus, 25% rimsulfuron, Du Pont De Nemours) is more persistent in alluvial soil suspensions (t(1/2)=7.5 days). The study of sorption of Titus and its two major metabolites (1 and 2) revealed that these three chemicals are potentially highly mobile in the studied soil: in suspension distribution coefficients of 0.0028, 0.125 and 0.149 cm3 g(-1) were obtained respectively. Given the instability of rimsulfuron in alkaline solutions, the pH effect was evaluated with metabolite 2 in water saturated Fontainebleau sand columns at pH 6, 8 and 10. Transport was found to be strongly dependent on pH; a linear relationship was obtained between pH and the retardation factor or the dispersion coefficient. In alluvial soil columns, rimsulfuron from Titus was found to be very mobile (R=1.2) and rapidly degraded into metabolites 1 and 2, which were transported at a similar velocity. Nevertheless, the risks of groundwater contamination by rimsulfuron seem very low, as it is rapidly degraded under dynamic conditions (t(1,2)=1.4 days). On the other hand the relatively stable metabolite 2 seems likely to persist in the soil and to be transported to the groundwater. Special attention should thus be given to this compound at least as long as its harmlessness is not demonstrated.

  9. Transportation Anslysis Simulation System

    SciTech Connect

    2004-08-23

    TRANSIMS version 3.1 is an integrated set of analytical and simulation models and supporting databases. The system is designed to create a virtual metropolitan region with representation of each of the region’s individuals, their activities and the transportation infrastructure they use. TRANSIMS puts into practice a new, disaggregate approach to travel demand modeling using agent-based micro-simulation technology. TRANSIMS methodology creates a virtual metropolitan region with representation of the transportation infrastructure and the population, at the level of households and individual travelers. Trips a planned to satisfy the population’s activity pattems at the individual traveler level. TRANSIMS then simulates the movement of travelers and vehicles across the transportation network using multiple modes, including car, transit, bike and walk, on a second-by-second basis. Metropolitan planners must plan growth of their cities according to the stringent transportation system planning requirements of the Interniodal Surface Transportation Efficiency Act of 1991, the Clean Air Act Amendments of 1990 and other similar laws and regulations. These require each state and its metropotitan regions to work together to develop short and long term transportation improvement plans. The plans must (1) estimate the future transportation needs for travelers and goods movements, (2) evaluate ways to manage and reduce congestion, (3) examine the effectiveness of building new roads and transit systems, and (4) limit the environmental impact of the various strategies. The needed consistent and accurate transportation improvement plans require an analytical capability that properly accounts for travel demand, human behavior, traffic and transit operations, major investments, and environmental effects. Other existing planning tools use aggregated information and representative behavior to predict average response and average use of transportation facilities. They do not account

  10. Transportation Anslysis Simulation System

    2004-08-23

    TRANSIMS version 3.1 is an integrated set of analytical and simulation models and supporting databases. The system is designed to create a virtual metropolitan region with representation of each of the region’s individuals, their activities and the transportation infrastructure they use. TRANSIMS puts into practice a new, disaggregate approach to travel demand modeling using agent-based micro-simulation technology. TRANSIMS methodology creates a virtual metropolitan region with representation of the transportation infrastructure and the population, at themore » level of households and individual travelers. Trips a planned to satisfy the population’s activity pattems at the individual traveler level. TRANSIMS then simulates the movement of travelers and vehicles across the transportation network using multiple modes, including car, transit, bike and walk, on a second-by-second basis. Metropolitan planners must plan growth of their cities according to the stringent transportation system planning requirements of the Interniodal Surface Transportation Efficiency Act of 1991, the Clean Air Act Amendments of 1990 and other similar laws and regulations. These require each state and its metropotitan regions to work together to develop short and long term transportation improvement plans. The plans must (1) estimate the future transportation needs for travelers and goods movements, (2) evaluate ways to manage and reduce congestion, (3) examine the effectiveness of building new roads and transit systems, and (4) limit the environmental impact of the various strategies. The needed consistent and accurate transportation improvement plans require an analytical capability that properly accounts for travel demand, human behavior, traffic and transit operations, major investments, and environmental effects. Other existing planning tools use aggregated information and representative behavior to predict average response and average use of transportation facilities. They do not

  11. Bioreactor Mass Transport Studies

    NASA Technical Reports Server (NTRS)

    Kleis, Stanley J.; Begley, Cynthia M.

    1997-01-01

    The objectives of the proposed research efforts were to develop both a simulation tool and a series of experiments to provide a quantitative assessment of mass transport in the NASA rotating wall perfused vessel (RWPV) bioreactor to be flown on EDU#2. This effort consisted of a literature review of bioreactor mass transport studies, the extension of an existing scalar transport computer simulation to include production and utilization of the scalar, and the evaluation of experimental techniques for determining mass transport in these vessels. Since mass transport at the cell surface is determined primarily by the relative motion of the cell assemblage and the surrounding fluid, a detailed assessment of the relative motion was conducted. Results of the simulations of the motion of spheres in the RWPV under microgravity conditions are compared with flight data from EDU#1 flown on STS-70. The mass transport across the cell membrane depends upon the environment, the cell type, and the biological state of the cell. Results from a literature review of cell requirements of several scalars are presented. As a first approximation, a model with a uniform spatial distribution of utilization or production was developed and results from these simulations are presented. There were two candidate processes considered for the experimental mass transport evaluations. The first was to measure the dissolution rate of solid or gel beads. The second was to measure the induced fluorescence of beads as a stimulant (for example hydrogen peroxide) is infused into the vessel. Either technique would use video taped images of the process for recording the quantitative results. Results of preliminary tests of these techniques are discussed.

  12. Cri-du-Chat Syndrome Cytogenetically Cryptic Recombination Aneusomy of Chromosome 5: Implications in Recurrence Risk Estimation.

    PubMed

    Ohnuki, Y; Torii, C; Kosaki, R; Yagihashi, T; Sago, H; Hayashi, K; Yasukawa, K; Takahashi, T; Kosaki, K

    2010-01-01

    Cri-du-chat syndrome is caused by haploinsufficiency of the genes on the distal part of the short arm of chromosome 5, and characteristic features include microcephaly, developmental delays, and a distinctive high-pitched mewing cry. Most cri-du-chat syndrome cases result from a sporadic de novo deletion that is associated with a low recurrence risk. On rare occasions, however, cri-du-chat syndrome with 5p monosomy can be accompanied by 5q trisomy. This combination is virtually always associated with parental large pericentric inversions. Among previously reported cri-du-chat syndrome cases with 5p monosomy accompanied by 5q trisomy, the aneusomy of chromosome 5 in all but one case was cytogenetically visible using G-banding. When an accompanying 5q trisomy is detected, a significant recurrence risk is expected. We here report on a patient with cri-du-chat syndrome phenotype who initially exhibited a normal karyotype on G-banding but in whom molecular analysis using multiplex ligation-dependent probe amplification and array comparative genomic hybridization revealed a 5p deletion accompanied by a 5q duplication. Parental chromosomal testing led to the identification of a very large pericentric inversion, of which breakpoints resided at the terminal regions of 5p15.31 and 5q35.1. This information was vital for counseling the family regarding the significantly high recurrence risk. PMID:21045963

  13. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira; Lei Zhou

    2000-01-30

    This is the second quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between Oct 1, 2000 and December 31, 2000. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 2: Addition of a foam generation and breaker system), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (d) Research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (e) Research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Research on instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), and Foam properties while transporting cuttings. (Task 12), (h) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members. The tasks Completed During This Quarter are Task 7 and Task 8.

  14. ABC transporters: bacterial exporters.

    PubMed Central

    Fath, M J; Kolter, R

    1993-01-01

    The ABC transporters (also called traffic ATPases) make up a large superfamily of proteins which share a common function and a common ATP-binding domain. ABC transporters are classified into three major groups: bacterial importers (the periplasmic permeases), eukaryotic transporters, and bacterial exporters. We present a comprehensive review of the bacterial ABC exporter group, which currently includes over 40 systems. The bacterial ABC exporter systems are functionally subdivided on the basis of the type of substrate that each translocates. We describe three main groups: protein exporters, peptide exporters, and systems that transport nonprotein substrates. Prototype exporters from each group are described in detail to illustrate our current understanding of this protein family. The prototype systems include the alpha-hemolysin, colicin V, and capsular polysaccharide exporters from Escherichia coli, the protease exporter from Erwinia chrysanthemi, and the glucan exporters from Agrobacterium tumefaciens and Rhizobium meliloti. Phylogenetic analysis of the ATP-binding domains from 29 bacterial ABC exporters indicates that the bacterial ABC exporters can be divided into two primary branches. One branch contains the transport systems where the ATP-binding domain and the membrane-spanning domain are present on the same polypeptide, and the other branch contains the systems where these domains are found on separate polypeptides. Differences in substrate specificity do not correlate with evolutionary relatedness. A complete survey of the known and putative bacterial ABC exporters is included at the end of the review. PMID:8302219

  15. Pyrophosphate Transport and Stones

    NASA Astrophysics Data System (ADS)

    Sayer, John A.; Carr, Georgina; Moochhala, Shabbir H.; Simmons, Nicholas L.

    2008-09-01

    Since the 1960's, inorganic pyrophosphate (PPi) has been known to inhibit apatite precipitation. Recent findings suggest that PPi plays a central role in the control of normal bone mineralization. Knockout mice have established the functional importance of PPi transmembrane transport, via the pyrophosphate transporter ANKH. The molecular nature and transport function of ANKH are reviewed. PPi is present in urine and ANKH is expressed in the cortical collecting duct where PPi transport to both the tubular lumen and renal interstitium may occur. Arginine vasopressin stimulation of cortical collecting duct cells grown on semi-permeable supports appears to upregulate apical ANKH expression, which we postulate may be a mechanism of stone inhibition during urinary concentration and supersaturation of calcium salts. Hypopyrophosphaturia may be a forgotten metabolic risk factor for stone formation and polymorphisms of the ANKH gene may underlie this defect. The physiological importance and clinical significance of PPi generation and transport in preventing idiopathic renal stone disease and nephrocalcinosis now needs to be established.

  16. Characterization of printing and laser trimming of DuPont 2000 series resistors on DuPont 951 {open_quotes}Green Tape{trademark}{close_quotes}

    SciTech Connect

    Morgenstern, H.; Bandler, S.; Barner, G.

    1996-10-01

    DuPont 2000 series resistors were reviewed and found to come closest to our requirement of 1% resistor tolerance over the expected 30-year life of our products. The evaluation performed involved the characterization of both the printing and trimming processes. The printing process was characterized for firing temperature print thickness, print direction, resistor geometry and encapsulant effect. Laser trimming was characterized by first finding an operating envelope and then selecting an operating point. The envelope was located by varying the trimming parameters and determining their acceptability to electrical and visual criteria. Samples from both the envelope and operating point were environmentally conditioned The conditioning included thermal shock temperature cycle, 1000-hour temperature aging, 1000-hour humidity aging, and a simulated gold/tin solder reflow.

  17. Prédiction des vibrations du stator d'une machine à réluctance variable en fonction du courant absorbé

    NASA Astrophysics Data System (ADS)

    Camus, F.; Gabsi, M.; Multon, B.

    1997-02-01

    In order to predict the radial vibration of the stator core of a Doubly Salient Switched Reluctance Motor (D.S.S.R.M.), different causes of vibrations are considered. In this kind of machine, electromagnetic stress is found to be the most significant cause of vibrations. The local magnetic stress distribution, depending on magnetic field and finally on the phase current, is calculated in the case of an unsatured operation. This magnetic stress acts in two ways: a tangential force (torque) and a radial attractive force. This radial force excites the vibration modes of the stator, this vibration behaviour is measured in the aligned position and is identified as a transfert function. Finally several experiments show the good accuracy of this simple model. This model will be later used to study the effect of phase current and of static converter on vibration and acoustic noise emitted by the D.S.S.R.M. L'étude du bruit et des vibrations dans le matériel électrique fait intervenir plusieurs systèmes physiques couplés. Le modèle complet est complexe et ne permet pas d'études paramétriques simples de la structure de la machine, de son alimentation et cela pour différents points de fonctionnement. Dans cet article est présenté un modèle simple permettant de prédire l'accélération radiale d'un Moteur à Réluctance Variable à Double Saillance (M.R.V.D.S.) en fonction du courant d'alimentation. Ce modèle permettra d'étudier ultérieurement l'influence de l'alimentation sur le comportement vibratoire de la machine. En premier lieu, les différentes sources de vibrations d'une machine tournante sont évoquées, pour finalement ne s'intéresser qu'aux efforts d'origine magnétique qui sont prépondérants dans les M.R.V.D.S. Le calcul de ces efforts en fonction du courant est présenté dans le cas d'une machine fonctionnant en régime linéaire (sans saturation magnétique). Ces efforts sont décomposés en une force tangentielle créant le couple de rotation

  18. The High Cost of Transportation.

    ERIC Educational Resources Information Center

    Rasicot, Julie

    1996-01-01

    Describes how school districts, faced with shrinking resources, have cut costs for student transportation. To combat rising transportation costs, districts have charged fees for student transportation, entered into private contracts, cut transportation services, used alternative fuels, and streamlined bus routes and schedules. (LMI)

  19. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Ergun Kuru; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Len Volk; Mark Pickell; Evren Ozbayoglu; Barkim Demirdal; Paco Vieira; Affonso Lourenco

    1999-10-15

    This report includes a review of the progress made in ACTF Flow Loop development and research during 90 days pre-award period (May 15-July 14, 1999) and the following three months after the project approval date (July15-October 15, 1999) The report presents information on the following specific subjects; (a) Progress in Advanced Cuttings Transport Facility design and development, (b) Progress report on the research project ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (c) Progress report on the research project ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (d) Progress report on the research project ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (e) Progress report on the research project ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Progress report on the instrumentation tasks (Tasks 11 and 12) (g) Activities towards technology transfer and developing contacts with oil and service company members.

  20. Transportation Institutional Plan

    SciTech Connect

    Not Available

    1986-08-01

    This Institutional Plan is divided into three chapters. Chapter 1 provides background information, discusses the purposes of the Plan and the policy guidance for establishing the transportation system, and describes the projected system and the plans for its integrated development. Chapter 2 discusses the major participants who must interact to build the system. Chapter 3 suggests mechanisms for interaction that will foster wide participation in program planning and implementation and provides a framework for managing and resolving the issues related to development and operation of the transportation system. A list of acronyms and a glossary are included for the reader's convenience. Also included in this Plan are four appendices. Of particular importance is Appendix A, which includes detailed discussion of specific transportation issues. Appendices B, C, and D provide supporting material to assist the reader in understanding the roles of the involved institutions.

  1. Lunar material transport vehicle

    NASA Technical Reports Server (NTRS)

    Fisher, Charles D.; Lyons, Douglas; Wilkins, W. Allen, Jr.; Whitehead, Harry C., Jr.

    1988-01-01

    The proposed vehicle, the Lunar Material Transport Vehicle (LMTV), has a mission objective of efficient lunar soil material transport. The LMTV was designed to meet a required set of performance specifications while operating under a given set of constraints. The LMTV is essentially an articulated steering, double-ended dump truck. The vehicle moves on four wheels and has two identical chassis halves. Each half consists of a chassis frame, a material bucket, two wheels with integral curvilinear synchronous motors, a fuel cell and battery arrangement, an electromechanically actuated dumping mechanism, and a powerful microprocessor. The vehicle, as designed, is capable of transporting up to 200 cu ft of material over a one mile round trip per hour. The LMTV is capable of being operated from a variety of sources. The vehicle has been designed as simply as possible with attention also given to secondary usage of components.

  2. Preface: Nonclassical Transport

    SciTech Connect

    Bolshov, L.; Kondratenko, P.; Pruess, K.

    2008-09-01

    Transport phenomena in highly heterogeneous media can be dramatically different from those in homogeneous media and therefore are of great fundamental and practical interest. Anomalous transport occurs in semiconductor physics, plasma physics, astrophysics, biology, and other areas. It plays an especially important role in hydrogeology because it may govern the rate of migration and degree of dispersion of groundwater contaminants from hazardous waste sites. The series of four articles in this special section of Vadose Zone Journal is devoted to transport phenomena in heterogeneous media in the context of geologic disposal of radioactive waste. It contains the results of joint investigations performed at the Nuclear Safety Institute of the Russian Academy of Sciences and Lawrence Berkeley National Laboratory in California. The work was supported by the U.S. DOE (under Contract No. DEAC02-05CH11231). The problems addressed in this research involve a broad range of space and time scales and were approached using modern methods of theoretical and computational physics, such as scaling analysis and diagrammatic techniques used before in critical phenomena theory. Special attention is paid to the asymptotics of concentration behavior (concentration tails). This issue is exceptionally important for the reliability assessments of radioactive waste disposal because, depending on the structure of the tails, concentrations at large distances from the source can differ by many orders of magnitude. In the first paper of this special section, Bolshov et al. (2008b) present an overview of field and laboratory observations that demonstrate nonclassical flow and transport behavior in geologic media. It is recognized that natural fracture networks as a rule have fractal geometry and can be classified as percolation systems. This is one of the main factors giving rise to anomalous transport in geologic media. Another important factor is the presence of contaminant traps provided by

  3. Intermodal Transportation, USACE Style

    SciTech Connect

    Grumski, K. M.; Coutts, P. W.

    2002-02-27

    The US Army Corps of Engineers (USACE) has developed project management techniques with a proven track record for safe and successful results for constructing large scale and massive projects such as improving our nations water transportation systems, flood control, bridges and dams. Applying many of these techniques to the Formerly Utilized Sites Remedial Action Program (FUSRAP) managed by USACE to remediate the environment is achieving the same safe and successful results as their construction projects. This paper examines the additional economics and improved safety results of using intermodal containers and a combination of rail and truck transportation conveyances to transport the contaminated soil and debris from the Linde FUSRAP site, located in Tonawanda, New York.

  4. Solute transport in groundwater

    NASA Astrophysics Data System (ADS)

    Dougherty, David E.

    Continued research interest in transport in the subsurface was demonstrated at the “Solute Transport in Groundwater” session held at the 1985 AGU Spring Meeting in Baltimore. This session, following on the heels of the very successful special symposium on “Coupling Geochemical and Hydrologic Models for Subsurface Solute Transport,” was organized by Lenny Konikow of the U.S. Geological Survey (USGS, Reston, Va.) and copresided by Steve Gorelick (USGS, Menlo Park, Calif.) and David Dougherty (Princeton University, Princeton, N.J.). Participation was strong, with 12 contributed papers and about 150 attendees. The papers addressed a wide variety of topics, ranging from the theoretical to the applied, from physics to numerical methods.

  5. Payload transportation at KSC

    NASA Technical Reports Server (NTRS)

    Donahue, M. E.

    1985-01-01

    Cargo ground processing at John F. Kennedy Space Center (KSC) involves either a horizointal or vertical mode of assembly and processing of the STS payloads. Consequently, cargos are commonly referred to as horizontal or vertical payloads. The process flow for each mode requires different facilities and transportation requirements. Occasionally, a mixed mission cargo containing both horizontal and vertical payload elements will require a combination of horizontal and vertical transportation between facilities. Some of the engineering challenges and innovative solutions to satisy the unique on-site payload transportation requirements at KSC. In particular, some of the more demanding design requirements of the multiuse mission support equipment are presented, and the resulting engineering designs and unique solutions are outlined.

  6. Prioritized Contact Transport Stream

    NASA Technical Reports Server (NTRS)

    Hunt, Walter Lee, Jr. (Inventor)

    2015-01-01

    A detection process, contact recognition process, classification process, and identification process are applied to raw sensor data to produce an identified contact record set containing one or more identified contact records. A prioritization process is applied to the identified contact record set to assign a contact priority to each contact record in the identified contact record set. Data are removed from the contact records in the identified contact record set based on the contact priorities assigned to those contact records. A first contact stream is produced from the resulting contact records. The first contact stream is streamed in a contact transport stream. The contact transport stream may include and stream additional contact streams. The contact transport stream may be varied dynamically over time based on parameters such as available bandwidth, contact priority, presence/absence of contacts, system state, and configuration parameters.

  7. Mars surface transportation options

    NASA Technical Reports Server (NTRS)

    Leitner, Jeffrey M.; Alred, John W.

    1986-01-01

    As the number of scientific experiments for the surface of Mars grows, the need for effective surface transportation becomes critical. Because of the diversity of the experiments proposed, as well as the desire to explore Mars from the equator to the poles, the optimum surface vehicle configuration is not obvious. Five candidate vehicles are described, with an estimate of their size and performance. In order to maximize the success of a manned Mars mission, it appears that two vehicles should be designed for surface transportation: an advanced long-range rover, and a remotely-piloted airplane.

  8. Design objectives - Air transportation

    NASA Technical Reports Server (NTRS)

    Beheim, M. A.

    1974-01-01

    The mainline of air transportation is expected to continue to be based on the medium to long haul turbine powered subsonic aircraft. With greater emphasis on energy conservation, there will be considerable interest in making additional progress in propulsion system efficiency. Continued improvement in turbofan engines is expected to occur, but there may be a less conventional approach in the background. Opportunities for expanding short haul air services will certainly materialize. The outlook for supersonic air transport is less clear because of complex political and economic factors.

  9. FAA Smoke Transport Code

    SciTech Connect

    Domino, Stefan; Luketa-Hanlin, Anay; Gallegos, Carlos

    2006-10-27

    FAA Smoke Transport Code, a physics-based Computational Fluid Dynamics tool, which couples heat, mass, and momentum transfer, has been developed to provide information on smoke transport in cargo compartments with various geometries and flight conditions. The software package contains a graphical user interface for specification of geometry and boundary conditions, analysis module for solving the governing equations, and a post-processing tool. The current code was produced by making substantial improvements and additions to a code obtained from a university. The original code was able to compute steady, uniform, isothermal turbulent pressurization. In addition, a preprocessor and postprocessor were added to arrive at the current software package.

  10. Mobile transporter path planning

    NASA Technical Reports Server (NTRS)

    Baffes, Paul; Wang, Lui

    1990-01-01

    The use of a genetic algorithm (GA) for solving the mobile transporter path planning problem is investigated. The mobile transporter is a traveling robotic vehicle proposed for the space station which must be able to reach any point of the structure autonomously. Elements of the genetic algorithm are explored in both a theoretical and experimental sense. Specifically, double crossover, greedy crossover, and tournament selection techniques are examined. Additionally, the use of local optimization techniques working in concert with the GA are also explored. Recent developments in genetic algorithm theory are shown to be particularly effective in a path planning problem domain, though problem areas can be cited which require more research.

  11. The Trojan. [supersonic transport

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Trojan is the culmination of thousands of engineering person-hours by the Cones of Silence Design Team. The goal was to design an economically and technologically viable supersonic transport. The Trojan is the embodiment of the latest engineering tools and technology necessary for such an advanced aircraft. The efficient design of the Trojan allows for supersonic cruise of Mach 2.0 for 5,200 nautical miles, carrying 250 passengers. The per aircraft price is placed at $200 million, making the Trojan a very realistic solution for tomorrows transportation needs. The following is a detailed study of the driving factors that determined the Trojan's super design.

  12. Coupled transport protein systems.

    PubMed

    Thatcher, Jack D

    2013-04-16

    This set of animated lessons provides examples of how transport proteins interact in coupled systems to produce physiologic effects. The gastric pumps animation depicts the secretion of hydrochloric acid into the gastric lumen. The animation called glucose absorption depicts glucose absorption by intestinal epithelial cells. The CFTR animation explains how the cystic fibrosis conductance transmembrane regulator (CFTR) functions as a key component of a coupled system of transport proteins that clears the pulmonary system of mucus and inhaled particulates. These animations serve as valuable resources for any collegiate-level course that describes these processes. Courses that might use them include introductory biology, biochemistry, biophysics, cell biology, pharmacology, and physiology.

  13. Automated transportable mass spectrometer

    NASA Astrophysics Data System (ADS)

    Echo, M. W.

    1981-09-01

    The need was identified for a mass spectrometer (MS) which can be conveniently transported among several facilities for rapid verification of the isotopic composition of special nuclear material. This requirement for a light weight, transportable MS for U and Pu mass analysis was met by deleting the gas chromograph (GC) portions of a Hewlett-Packard Model 5992 Quadrupole GCMS and substituting a vacuum lock sample entry system. A programmable power supply and vacuum gauge were added and circuitry modifications were made to enable use of the supplied software.

  14. Introduction to radiation transport

    SciTech Connect

    Olson, G.L.

    1998-12-31

    This lecture will present time-dependent radiation transport where the radiation is coupled to a static medium, i.e., the material is not in motion. In reality, radiation exerts a pressure on the materials it propagates through and will accelerate the material in the direction of the radiation flow. This fully coupled problem with radiation transport and materials in motion is referred to as radiation-hydrodynamics (or in a shorthand notation: rad-hydro) and is beyond the scope of this lecture.

  15. Smart vehicular transportation systems

    SciTech Connect

    Little, C.Q.; Wilson, C.W.

    1997-05-01

    This work builds upon established Sandia intelligent systems technology to develop a unique approach for the integration of intelligent system control into the US Highway and urban transportation systems. The Sandia developed concept of the COPILOT controller integrates a human driver with computer control to increase human performance while reducing reliance on detailed driver attention. This research extends Sandia expertise in sensor based, real-time control of robotics systems to high speed transportation systems. Knowledge in the form of maps and performance characteristics of vehicles provides the automatic decision making intelligence needed to plan optimum routes, maintain safe driving speeds and distances, avoid collisions, and conserve fuel.

  16. W.E.B. Du Bois and Filipino/a American Exposure Programs to the Philippines: Race Class Analysis in an Epoch of "Global Apartheid"

    ERIC Educational Resources Information Center

    Viola, Michael Joseph

    2016-01-01

    The article highlights the ongoing relevance of W.E.B. Du Bois for the global analysis of race and class. Engaging scholarly debates that have ensued within the educational subfields of critical race theory (CRT) and (revolutionary) critical pedagogy, the article explores how a deeper engagement with Du Bois's ideas contributes theoretically and…

  17. The W. E. B. DuBois and Booker T. Washington Debate: Effects upon African American Roles in Engineering and Engineering Technology

    ERIC Educational Resources Information Center

    Johnson, Keith V.; Watson, Elwood

    2004-01-01

    The messages of Booker T. Washington and W. E. B. DuBois could not have been more diverse. The philosophical rivalry between Washington and DuBois has deep historical roots. To be on the same side fighting for the same purpose, progress, and uplifting of the Black race, these two Black intellectuals harbored radically divergent views on how to…

  18. Actes du colloque sur le bilinguisme, Universite de Neuchatel, 14/15 Septembre, 1981 (Proceedings of the Colloquium on Bilingualism, University of Neuchatel, September 14-15, 1981).

    ERIC Educational Resources Information Center

    TRANEL, 1982

    1982-01-01

    This issue contains proceedings of a colloquium on linguistics at the University of Neuchatel: (1) "Propositions epistemologiques pour une etude du bilinguisme (Epistemological Propositions for a Study of Bilingualism)," by B. Py; (2) "Comment on di ca? Prolegomenes a une etude de la composante semantique du langage des migrants (How Do You Say…

  19. Evaluation de la tenue du partogramme dans une maternité universitaire

    PubMed Central

    Limam, Manel; Zedini, Chekib; El Ghardallou, Meriem; Mellouli, Menel; Bougmiza, Iheb; Sahli, Jihène; Khairi, Hédi; Mtiraoui, Ali; Ajmi, Thouraya Nabli

    2015-01-01

    Introduction La mortalité maternelle est un problème majeur de santé mondiale. Une grande proportion de ces décès serait évitable par des soins adéquats, une aide à l'accouchement, la disponibilité des soins d'urgence et l'utilisation des outils d'aide à la décision tels que le partogramme. L'objectif était d’évaluer l’écart entre ce qui est censé être fait et ce qui est fait réellement pour les différents paramètres situés dans le partogramme au sein d'une maternité de 3ème niveau et élaborer des recommandations pour la mise en place d'un plan d'action. Méthodes Il s'agit d'une étude descriptive rétrospective par audit clinique, effectuée sur un échantillon de 400 dossiers obstétricaux des parturientes ayant accouchées dans la maternité du CHU Farhat Hached durant l'année 2011. Le référentiel utilisé est celui réalisé par l'Agence Nationale d'Accréditation et d'Evaluation en Santé en l'an 2000, concernant la qualité de la tenue du partogramme. Résultats La majorité des critères d’évaluation portant sur la présentation du partogramme était conforme. Deux critères concernant la variété de la présentation et le rythme cardiaque fœtal étaient non conformes parmi ceux portant sur la surveillance du fœtus. Plusieurs critères en rapport avec la surveillance de la mère étaient non conformes. Aucun des critères portant sur les traitements administrés et les marqueurs d’évènements n'est conforme. Les critères portant sur la naissance et la surveillance immédiate qui étaient non conformes sont: le début des efforts expulsifs, le mode d'accouchement, l’état du périnée, la délivrance et la révision utérine. Conclusion La véritable démarche de l'audit clinique se doit d'aller au-delà du recueil et de l'analyse des données, le but final étant l'amélioration des pratiques. PMID:26516400

  20. Pleurésie massive après chirurgie du cancer de sein et arrêt précoce du Tamoxifène: à propos d’‘une observation

    PubMed Central

    Ngombe, Léon Kabamba; Kangulu, Ignace Bwana; Nday, Chantal Mwenze; Tshanda, Migrette Ngalula; Ngoy Lumbule, John; Matanga, Pierre Mbayo; Sampatwa, Olivier Ngoy; Nzaji, Michel Kabamba

    2014-01-01

    Nous rapportons un cas de pleurésie massive droite probablement métastasique accompagnée d'un lymphœdème du membre supérieur droit ayant fait suite à une mastectomie et curage ganglionnaire indiqués pour un carcinome lobulaire du sein droit, associée à un arrêt précoce de la prise de Tamoxifène, vécu à Lubumbashi. PMID:25374634

  1. Carcinoïde primitif du rein métastasant après 12 ans

    PubMed Central

    Bacha, Dhouha; Lahmar, Ahlem; Gharbi, Lassad; Slama, Sana Ben; Bouraoui, Saadia; Chatti, Samia; Regaya, Sabeh Mzabi

    2016-01-01

    Les carcinoïdes primitifs du rein sont rares avec une centaine de cas rapportés dans la littérature. Sur le plan histologique, il s'agit d'une tumeur bien différenciée dont la morphologie rejoint souvent celle des carcinoïdes dans les autres localisations. Nous rapportons un cas de carcinoïde primitif du rein survenant chez un homme de 41 ans, découvert à la suite de métastases hépatiques. La tumeur était particulière par son architecture tubulo-papillaire, suggérant à tort le diagnostic de carcinome papillaire du rein. Ce diagnostic a été redressé 12 ans après, à la suite de l'apparition d'autres métastases hépatiques, osseuses et pulmonaires. PMID:27217899

  2. Lipome du corps calleux: à propos d'un cas avec revue de littérature

    PubMed Central

    Zhari, Bouchra; Mattiche, Houda; Boumdine, Hassan; Amil, Touriya; Ennouali, Hassan

    2015-01-01

    Le lipome du corps calleux est une malformation congénitale très rare, qui peut être associée à des degrés divers de dysgénésie du corps calleux. Son extension dans le ventricule latéral est encore plus rare. Il est souvent asymptomatique, mais peut se présenter par une épilepsie, hémiplégie, démence ou de simples céphalées. La tomodensitométrie et l'imagerie par résonance magnétique permettent facilement le diagnostic. Nous rapportons le cas d'une jeune fille de 14 ans, souffrant de simples céphalées, chez qui on découvre un lipome du corps calleux avec extension au ventricule latéral. PMID:26526933

  3. Carcinome épidermoïde du sein: à propos d’un cas et revue de la literature

    PubMed Central

    Ziyadi, Mounia; Boujoual, Majdouline; Raiteb, Hanane; Babahabib, My Abdellah; Kouach, Jawad; Moussaoui, Driss Rahali; Dehayni, Mohammed

    2016-01-01

    Le carcinome épidermoïde du sein est une tumeur rare, d'origine métaplasique l'ethiopathogénie est controversé, le diagnostic est histologique après avoir éliminé l'origine métastatique, la clinique et la radiologie ne sont pas spécifique le traitement rejoint celui du carcinome canalaire infiltrant, le pronostic est péjoratif liée à la taille tumorale et à l'envahissement ganglionnaire, on rapporte un cas de carcinome épidermoïde du sein chez une patiente de 39 ans ayant consulté au service de gynécologie obstétrique de hôpital militaire de Rabat, et à travers cette observation on va mettre le point sur les différentes caractéristiques de cette entité qui reste rare.

  4. Celecoxib Induced Tumor Cell Radiosensitization by Inhibiting Radiation Induced Nuclear EGFR Transport and DNA-Repair: A COX-2 Independent Mechanism

    SciTech Connect

    Dittmann, Klaus H. Mayer, Claus; Ohneseit, Petra A.; Raju, Uma; Andratschke, Nickolaus H.; Milas, Luka; Rodemann, H. Peter

    2008-01-01

    Purpose: The purpose of the study was to elucidate the molecular mechanisms mediating radiosensitization of human tumor cells by the selective cyclooxygenase (COX)-2 inhibitor celecoxib. Methods and Materials: Experiments were performed using bronchial carcinoma cells A549, transformed fibroblasts HH4dd, the FaDu head-and-neck tumor cells, the colon carcinoma cells HCT116, and normal fibroblasts HSF7. Effects of celecoxib treatment were assessed by clonogenic cell survival, Western analysis, and quantification of residual DNA damage by {gamma}H{sub 2}AX foci assay. Results: Celecoxib treatment resulted in a pronounced radiosensitization of A549, HCT116, and HSF7 cells, whereas FaDu and HH4dd cells were not radiosensitized. The observed radiosensitization could neither be correlated with basal COX-2 expression pattern nor with basal production of prostaglandin E2, but was depended on the ability of celecoxib to inhibit basal and radiation-induced nuclear transport of epidermal growth factor receptor (EGFR). The nuclear EGFR transport was strongly inhibited in A549-, HSF7-, and COX-2-deficient HCT116 cells, which were radiosensitized, but not in FaDu and HH4dd cells, which resisted celecoxib-induced radiosensitization. Celecoxib inhibited radiation-induced DNA-PK activation in A549, HSF7, and HCT116 cells, but not in FaDu and HH4dd cells. Consequentially, celecoxib increased residual {gamma}H2AX foci after irradiation, demonstrating that inhibition of DNA repair has occurred in responsive A549, HCT116, and HSF7 cells only. Conclusions: Celecoxib enhanced radiosensitivity by inhibition of EGFR-mediated mechanisms of radioresistance, a signaling that was independent of COX-2 activity. This novel observation may have therapeutic implications such that COX-2 inhibitors may improve therapeutic efficacy of radiation even in patients whose tumor radioresistance is not dependent on COX-2.

  5. Evolution des quasiparticules nodales du cuprate supraconducteur YBa2Cu3Oy en conductivite thermique

    NASA Astrophysics Data System (ADS)

    Rene de Cotret, Samuel

    Ce memoire presente des mesures de conductivite thermique sur les supraconducteurs YBCO et Tl-2201 afin de statuer sur la presence possible d'un point critique quantique (QCP) dans le diagramme de phase de cuprates. Ce point critique quantique serait a l'origine de la reconstruction de la surface de Fermi, d'un large cylindre de trous en de petites poches de trous et d'electrons. La conductivite thermique dans le regime T → 0 permet d'extraire une quantite purement electronique liee aux vitesses de Fermi et du gap, au noeud. Une discontinuite dans cette quantite pourrait signaler la traversee du dopage critique qui reconstruit la surface de Fermi. Plusieurs sondes experimentales distinguent une transition de phase ou un crossover a T* a temperature finie. D'autres sondes mettent en evidence une transition de phase sous l'effet d'un champ magnetique. La presence ou non de cet ordre, a temperature et champ magnetique nul questionne la communaute depuis plusieurs annees. Dans cette etude, nous detectons une variation brusque de kappa0/T a p = 0.18 dans YBCO et a p = 0.20 dans Tl-2201. Ces sauts sont interpretes comme un signe de la transition a temperature nulle et sont en faveur d'un QCP. Le manque de donnees d'un meme materiau a ces dopages ne permet pas de valider hors de tout doute l'existence d'un point critique quantique. Le modele theorique YRZ decrit aussi bien les donnees de conductivite thermique. Des pistes de travaux experimentaux a poursuivre sont proposees pour determiner la presence ou non du QCP de facon franche. Mots-cles : Supraconducteurs, cuprates, conductivite thermique, point critique quantique.

  6. Les ruptures traumatiques du tendon quadricipital: à propos de 3 cas

    PubMed Central

    Benyass, Youssef; Chafry, Bouchaib; Koufagued, Kaldadak; Bouabid, Salim; Chagar, Belkacem

    2015-01-01

    Les ruptures traumatiques du tendon quadricipital sont rares, elles surviennent préférentiellement après 40 ans, suite à un traumatisme indirect chez le sportif (flexion contrariée du genou) ou traumatisme banal chez le sédentaire. La tendinopathie préexistante est fréquente. La rupture est le plus souvent totale et siège au corps du tendon 60% des cas ou décallotement quadricipital au bord supérieur de la rotule (40% des cas). Le diagnostic est essentiellement clinique. Les examens complémentaires (échographie et imagerie par résonance magnétique) sont utiles et appuient le diagnostique, mais sont souvent faussement rassurants hormis la radiographie qui montre une rotule basse. Le traitement essentiellement chirurgical associé à la rééducation fonctionnelle donne des résultats largement meilleurs. Le délai d'intervention est un facteur pronostic très important. Les auteurs rapportent 03cas de rupture de tendon quadricipital. L’âge moyen est de 50ans. Ils ont été traités chirurgicalement et revus régulièrement, avec un recul de 16 mois pour apprécier l’évolution. Les résultats ont été très bons chez 02 cas et bon chez 01 cas. L'amélioration a été très nette selon les critères: marche, douleur et reprise d'activité physique. PMID:26985261

  7. Physical mapping in the Cri du Chat region on human chromosome 5

    SciTech Connect

    Church, D.M.; Bengtsson, U.; Niebuhr, E.

    1994-09-01

    The Cri du Chat syndrome is a segmental aneusomy associated with deletions in the short arm of human chromosome 5. More specifically, the cytogenetic band 5p15.2 must be deleted in order to manifest the typical phenotypic signs. We have studied several cell lines from individuals who have chromosomal abnormalities within this cytogenetic band but who do not have typical Cri du Chat syndrome. In fact, several individual studied have no discernible features of this syndrome. Using fluorescent in situ hybridization (FISH) analysis and PCR analysis on somatic cell hybrids we have mapped the breakpoints relative to each other within this band. There is a great degree of phenotypic heterogeneity between several of the patients, even those which share common breakpoints. This heterogeneity makes it very difficult to narrow the region of interest to a very small (<1 Mb) region. In order to more thoroughly analyze this region, we have assembled a yeast artificial chromosome (YAC) contig of part of this region. This contig has been analyzed for STS content and covers approximately a 1.5-2.0 Mb region within 5p15.2. In addition, we have constructed a radiation hybrid map of the region. The YACs contained within the minimal contig have been used as hybridization probes to isolate corresponding cosmid clones within the region of interest. These cosmids, in turn, are being utilized to obtain potential exons using exon amplification. Several cosmids within this region have been isolated by STS content and potential exons have been isolated from them. These exons have been used as probes to isolate cDNA clones from the region. It is our hope that isolation of genes throughout the region of interest will allow a better understanding of the etiology of Cri du Chat.

  8. Application du concept de maillon faible à un critère d'endurance multiaxial

    NASA Astrophysics Data System (ADS)

    Flacelière, L.; Morel, F.; Palin-Luc, T.

    2002-12-01

    En fatigue à grand nombre de cycle, il est aujourd'hui admis que la distribution des contraintes, ainsi que la taille des composants, sont responsables de variations de la limite de fatigue. Sous chargement uniaxial ou multiaxial, on peut montrer qu'une approche statistique dite du maillon le plus faible, combiné à un critère multiaxial d'endurance basé sur une analyse micro plastique, permet de prédire la limite de fatigue de plusieurs matériaux métalliques. Quatre types de chargement sont analysés (traction-compression, torsion, flexion rotative et flexion plane), puis comparées aux résultats expérimentaux, pour une fonte et deux aciers haute résistance. L'approche statistique proposée permet d'intégrer un certain nombre d'aspects: la dispersion des données pour tous types de chargement, l'effet de gradient et l'influence de la présence de défauts matériaux. Enfin, ce modèle rend également compte de la diminution de la limite de fatigue avec l'augmentation du volume contraint. Les prédictions des probabilités de rupture sont raisonnables bien que seules des limites de fatigue relatives à des probabilités de rupture de 50% soient utilisées pour l'identification des paramètres du modèle.

  9. Diagnostic étiologique du diabète insipide central: à propos de 41 cas

    PubMed Central

    Chaker, Fatma; Chihaoui, Melika; Yazidi, Meriem; Slimane, Hedia

    2016-01-01

    La survenue d'un syndrome polyuro-polydipsiqueavec des urines hypotoniques nécessite une stratégie diagnostique rigoureuse. Le but de cette étude était d’étudier les modalités de diagnostic du diabète insipide central. A travers une étude rétrospective de 41 cas de diabète insipide central(DIC) colligés au service d'Endocrinologie à l'hôpital de la Rabta de Tunis, allant de l'année 1990 à l'an 2013, nous avons relevé les circonstances de découverte du DIC, les anomalies du bilan anté-hypophysaire etde l'imagerie hypophysaire. Le DIC était post opératoire chez 20 patients. La diurèse moyenne de 24 heures était significativement plus élevée chez les patients ayant un DIC en dehors d'un contexte chirurgical. L’épreuve de restriction hydrique était concluante chez tous les patients qui en ont bénéficié. En dehors d'un contexte neurochirurgical, les causes infiltratives étaient retrouvées chez 6 patientset les causes tumorales chez 6 patients. Le DIC était associé à une selle turcique vide dans 1 cas et idiopathique chez 3 malades. L'imagerie par résonnance magnétique hypothalamo-hypophysaire et le bilan anté-hypophysaire sont systématiques en dehors d'un contexte de chirurgie hypophysaire et d'une polydipsie primaire évidente. PMID:27642481

  10. DuPont/Oberlin microfiltration technology. Applications analysis report. Final report

    SciTech Connect

    Not Available

    1991-10-01

    The DuPont/Oberlin microfiltration technology demonstration was conducted under the SITE program at the Palmerton Zinc Superfund site in Palmerton, Pennsylvania, in April and May 1990. During the demonstration, the microfiltration system achieved zinc and total suspended solids (TSS) removal efficiencies of about 99.95 percent, and a filter cake solids content of 41 percent. The filter cake contained no free liquids, and a composite sample from all the demonstration runs passed both the extraction procedure toxicity characteristic leaching procedure (TCLP) test. The filtrate met applicable National Pollutant Discharge Elimination System permit limits for metals and TSS.

  11. Xenotransplanted human prostate carcinoma (DU145) cells develop into carcinomas and cribriform carcinomas: ultrastructural aspects.

    PubMed

    Gilloteaux, Jacques; Jamison, James M; Neal, Deborah R; Summers, Jack L; Taper, Henryk S

    2012-10-01

    Androgen-independent, human prostate carcinoma cells (DU145) develop into solid, carcinomatous xenotransplants on the diaphragm of nu/nu mice. Tumors encompass at least two poorly differentiated cell types: a rapidly dividing, eosinophilic cell comprises the main cell population and a few, but large basophilic cells able to invade the peritoneal stroma, the muscular tissue, lymph vessels. Poor cell contacts, intracytoplasmic lumina, and signet cells are noted. Lysosomal activities are reflected by entoses and programmed cell deaths forming cribriform carcinomas. In large tumors, degraded cells may align with others to facilitate formation of blood supply routes. Malignant cells would spread via ascites and through lymphatics.

  12. Lac du Flambeau Band of Lake Superior Chippewa Indians Strategic Energy Plan

    SciTech Connect

    Bryan Hoover

    2009-11-16

    This plan discusses the current energy use on the Lac du Flambeau Reservation, the current status of the Tribe's energy program, as well as the issues and concerns with energy on the reservation. This plan also identifies and outlines energy opportunities, goals, and objectives for the Tribe to accomplish. The overall goal of this plan is to address the energy situation of the reservation in a holistic manner for the maximum benefit to the Tribe. This plan is an evolving document that will be re-evaluated as the Tribe's energy situation changes.

  13. Curiethérapie dans le traitement palliatif du cancer de l’œsophage

    PubMed Central

    Toulba, Ahmedou; Bakkali, Hanae; Boutayeb, Salwa; Kebdani, Tayeb; Ahid, Samir; Benjaafar, Noureddine

    2015-01-01

    Les patients atteints du cancer de l’œsophage ont souvent une maladie localement avancée, la dysphagie est le symptôme majeur chez la plupart de ces patients, plusieurs modalités thérapeutiques ont été utilisées pour améliorer cette dysphagie. Le but de ce travail est d’étudier l'efficacité et la tolérance de la curiethérapie haut débit de dose (HDR) endo-luminale dans le traitement palliatif des cancers de l’œsophage inopérable. Sur une période de 15 ans, l’étude a inclus les patients atteints de cancer de l’œsophage inopérable et/ou métastatique avec une dysphagie, sans extension à l'hypopharynx ou a la trachée et qui ont bénéficié d'une curiethérapie HDR avec ou sans radiothérapie externe à visée palliative. Au total 46 patients ont été inclus dans l’étude, 58,7% étaient des hommes, 42,2% avaient une dysphagie grade 2 et 37,8% étaient aphagiques, 78,6% des patients étaient performance satus PS 2, l'amaigrissement à été trouvé chez 81,4%, la localisation de la tumeur était surtout au niveau du tiers moyen et inférieur dans 97,8%, la hauteur médiane de la tumeur était de 7 cm (5,5-9), le carcinome épidermoïde était le type histologique le plus fréquent chez 31 patients (70,5%). Après un médiane de suivi de 5 mois, l'amélioration de la dysphagie a été retrouvée chez 76% des malades (p1]. L′incidence la plus élevée est observée dans certains pays notamment en Asie et en Afrique, et l′incidence dans les pays développés occidentaux est en augmentation [2]. Selon le registre du cancer de Rabat 2006-2008, le cancer de l’œsophage est rare et constitue 1,5% de tous les cancers chez l'homme [3]. Le taux de survie globale à 5 ans est de 8%, avec 80% des décès liés à l’évolution locale de la maladie [4]. Pour la minorité des patients avec une maladie localisée, le traitement par radiochimiothérapie concomitante avec ou sans chirurgie permet une amélioration de la survie [5]. Plus de 50

  14. Aspects cliniques des cancers bronchopulmonaires primitifs au service d'oncologie du CHUA-HUJRA Antananarivo

    PubMed Central

    Refeno, Valéry; Hasiniatsy, Nomeharisoa Rodrigue Emile; Andrianandrasana, Ny Ony Tiana Florence; Ramahandrisoa, Andriatsihoarana Voahary Nasandratriniavo; Rakotonarivo, Jean Marc; Maevazaka, Joée Larissa; Rakotovao, Hanitrala Jean Louis; Rafaramino, Florine

    2015-01-01

    Le retard de diagnostic des cancers broncho-pulmonaires est l'une des sources du retard de leur prise en charge dans les pays en développement. A notre connaissance, l'aspect clinique des cancers broncho-pulmonaires au Centre Hospitalier Universitaire d'Antananarivo-Hôpital Universitaire Joseph Ravoahangy Andrianavalona (CHUA-HUJRA) n'a jamais été étudié. L'objectif était de décrire les aspects cliniques des cancers broncho-pulmonaires primitifs dans le plus grand centre de cancérologie de Madagascar. C'est une étude rétrospective et descriptive des patients atteints de cancers broncho-pulmonaires primitifs vus au service d'oncologie du CHUA-HUJRA du 1er janvier 2008 au 31 décembre 2013. Nous avons recensé 101 patients (80 hommes et 21 femmes). Les circonstances de découverte sont principalement la toux chronique (n = 29), la dyspnée (n = 16) et l'association d'une hémoptysie à la toux chronique (n = 12). Soixante et onze patients avaient un index de performans status ≥ à 2 au moment du diagnostic. On a retrouvé des bacilles de Koch actives dans le crachat de deux patients. Le délai moyen entre l'apparition des premiers signes et la première consultation était de 11 mois. Le délai moyen entre la première consultation et le diagnostic anatomopathologique était de 3 mois. Le cancer broncho-pulmonaire peut avoir des manifestations cliniques non spécifiques parfois trompeuses qui peuvent retarder leur prise en charge. De ce fait, il doit être recherché devant tout signe respiratoire persistant. Par ailleurs, le délai de prise en charge pré-hospitalière et hospitalière de ces cancers doit être amélioré. PMID:26958134

  15. Albumin activation of urinary amylase as determined with the Du Pont aca.

    PubMed

    Garber, C C; Carey, R N

    1978-04-01

    Protein activation of urinary alpha-amylase (EC 3.2.1.1) activity was observed during an evaluation of the Du Pont aca procedure for the determination of urinary alpha-amylase. This activation effect became constant for urinary albumin concentrations exceeding 1.50 g/liter. It is recommended that urinary alpha-amylase be analyzed with sufficient albumin added to maximize this effect. The aca alpha-amylase procedure is compared to an amyloclastic method for both serum and urine analysis. Expected ranges are presented for the aca method for serum and urinary amylase, amylase clearance, and the amylase clearance/creatinine clearance ratio.

  16. [[The Lactéol's laboratory of Dr Boucard (Laboratoire du Dr Boucard].

    PubMed

    Raynal, Cécile; Lefebvre, Thierry

    2016-03-01

    Shortly before 1910, Dr Boucard creates his laboratory in Paris. It manufactures and sells a drug based on lactic ferments the " Lactéol du Dr Boucard" (Dr's Boucard Lactéol) that will make the fortune of the physician. The article explains Dr Boucard's life and his relationship with the arts (painting and photography), and tells the story of his laboratory until the 2000s, referring to the pharmacists who succeeded them, as well as the various buildings where were elaborated Lactéol's variants. PMID:27281930

  17. La luxation chronique du coude chez l'enfant: à propos de 20 cas

    PubMed Central

    Atarraf, Karima; Arroud, Mounir; Chater, Lamiae; Afifi, My Abderrahmane

    2014-01-01

    La luxation négligée du coude chez l'enfant est peu fréquente dans les pays industrialisés, elle n'est pas en revanche rare dans notre contexte. Nous rapportons une série de 20 cas, colligée au service d'Orthopédie Pédiatrique du CHU HASSAN II de Fès, sur une période de 4 ans. En effet, 14 malades étaient de sexe masculin, avec un âge moyen de 8,5 ans. Le mécanisme principal était la chute d'olivier. Le délai de consultation était très variable. 19 enfants ont été traités traditionnellement. La raideur constituait le motif principal de consultation. Avec une flexion inférieure à 70°. Un seul malade avait présenté un syndrome de Volkmann. La luxation était isolée et postéro-externe dans la majorité des cas. La voie d'abord médiane postérieure était adoptée chez tous nos malades. 15 patients ont bénéficié d'une arthrolyse avec arthrodèse provisoire. La rééducation était systématique. Le résultat a été bon avec une flexion à 90° et un secteur de mobilité supérieur à 60° chez 9 de nos malades sur un recul de 3 ans. En définitive, la luxation invétérée du coude est une pathologie du milieu rural; la facilité d'accès au soin reste la meilleure prévention. PMID:25574324

  18. [The Bulletin du cancer: the years before the First World War].

    PubMed

    Bernaudin, Jean-François

    2013-12-01

    Three years after its founding in 1909, the Association française pour l'étude du cancer is a major scientific society developing transdisciplinary debates particularly on innovative therapeutics in cancer, such as the developing use of radium. The Association at that time assembles together all the French medical elite. Reading the Bulletin offers a clear view of the brilliant monthly debates. First World War stopped the life of the Association for four years. After this break, the set up of dedicated centers for cancer treatment was responsible for a major turn in the Association's life.

  19. O'Connell Effect in Early-Type Contact(?) Binaries: du Boo and AG Vir

    NASA Astrophysics Data System (ADS)

    Pribulla, Theodor; Vaňko, Martin; Chochol, Drahomír; Hambálek, L'ubomıır; Parimucha, Štefan

    2010-12-01

    O'Connell effect in early-type close eclipsing binaries is not caused by solar-type spots. In most early-type contact binaries it has the same sign: maximum following the primary minimum being the brighter of the two. Broadening functions of two early-type systems, DU Boo and AG Vir, do not show presence of dark solar-type spots in spite of strong light-curve asymmetry but indicate departures from the Roche model and/or possibly additional structures (stream, disc, etc.).

  20. A case of recurrent facial pain associated with a Pourfour du Petit syndrome: a new entity?

    PubMed

    Collongues, Nicolas; Labouret, Pascale; Speeg, Claude; de Seze, Jérôme

    2014-02-01

    We report the case of a 38-year-old woman with a history of migraine who experienced an association of recurrent unilateral facial pain and Pourfour du Petit syndrome. The episodes occurred for between a few seconds and up to 3 minutes up to 6 times a day mimicking short-lasting unilateral neuralgiform headaches with cranial autonomic symptoms. No lesional cause was found and the use of topiramate led to a nearly complete disappearance of the episodes. This new entity raises the question of a novel autonomic dysfunction in short-lasting unilateral neuralgiform headaches with cranial autonomic symptoms or an unexpected presentation of migraine.

  1. Etude descriptive et analytique du cancer de l’œsophage au Togo

    PubMed Central

    Oumboma, Bouglouga; Mawuli, Lawson-Ananissoh Laté; Aklesso, Bagny; Laconi, Kaaga; Datouda, Redah

    2014-01-01

    Introduction Décrire les aspects épidémiologiques, cliniques, endoscopiques et histologiques du cancer de l’œsophage (CO) au Togo. Méthodes Il s'agit d'une étude rétrospective descriptive et analytique menée sur 8 ans (Janvier 2005-Décembre 2012) dans le service d'hépato-gastroentérologie (HGE) du CHU Campus de Lomé. Etaient inclus les dossiers des patients hospitalisés pour CO confirmé histologiquement. Résultats Sur 8 ans, 24 patients remplissant nos critères d'inclusion ont été retenus soit 3cas de CO par an et 0,55% des hospitalisations. L’âge moyen des patients était de 57,08 ans (extrêmes: 32 et 82 ans). La dysphagie et l’épigastralgie étaient les motifs d'hospitalisation les plus rencontrés. L'alcool (n=15), le tabac (n=13) étaient les facteurs de risque les plus présents. A la fibroscopie, les lésions étaient ulcéro-bourgeonnantes et hémorragiques (n=12), ulcéro-bourgeonnantes (n=5); ces lésions siégeaient au niveau du 1/3 inférieur (n= 11), à l'union 1/3 supérieur 1/3moyen de l’œsophage (n= 13) et aucun au niveau du 1/3 supérieur. Seize lésions étaient des carcinomes épidermoïdes et 3 des adénocarcinomes. L’évolution dans le service a été fatale dans 2cas; 16 patients avaient été transférés en chirurgie pour des soins palliatifs et 5 patients (20,8%) étaient perdus de vue. Conclusion Le CO semble en augmentation au Togo. L'alcool et le tabac sont les facteurs de risque et le pronostic sévère dans notre série est lié au retard diagnostic. Son dépistage précoce passe par une consultation rapide devant toute dysphagie chez un sujet de 50 ans et plus. PMID:25883742

  2. L’identification et traitement du trouble panique avec ou sans agoraphobie

    PubMed Central

    Foldes-Busque, Guillaume; Marchand, André; Landry, Pierre

    2007-01-01

    RÉSUMÉ OBJECTIF Renseigner les médecins de première ligne au sujet de l’identification précoce, du diagnostic et du traitement du trouble panique avec ou sans agoraphobie (TP/A). QUALITÉ DES DONNÉES Les données et recommandations présentées proviennent d’une recension des écrits scientifiques réalisée via les banques de données PsycLIT, PsyINFO et MEDLINE (1985 à 2006) en utilisant les descripteurs panic disorder, psychotherapy, psychosocial treatment, treatment et pharmacotherapy. Les recommandations formulées par les auteurs s’appuient sur des données probantes provenant d’études d’excellente qualité. Les informations concernant le diagnostic et l’évaluation du TP/A proviennent d’études épidémiologiques récentes, de consensus et d’opinions d’experts. PRINCIPAL MESSAGE Le TP/A est un trouble psychiatrique souvent rencontré en médecine de première ligne, mais il est fréquemment sous-diagnostiqué et sous-traité. L’identification précoce de ce trouble demande une attention particulière aux symptômes médicalement inexpliqués et, le cas échéant, le médecin doit utiliser des questions spécifiques permettant d’identifier d’éventuelles attaques de panique et de cerner leur signification pour le patient. Le traitement de premier choix pour ce trouble est une psychothérapie d’orientation cognitivo-comportementale administrée par un psychologue ou un psychiatre spécialisé. Si de telles ressources ne sont pas disponibles, le médecin peut opter pour un traitement psychopharmacologique. CONCLUSION Les médecins de famille peuvent jouer un rôle central dans l’identification et le traitement des patients souffrant d’un TP/A. PMID:17934032

  3. Cause inhabituelle d'une infection respiratoire récidivante: hypoplasie du poumon gauche

    PubMed Central

    Zidane, Abdelfettah; Lahkim, Mohammed; Chafik, AChafik

    2013-01-01

    L'hypoplasie pulmonaire unilatérale est une malformation congénitale rare qui peut être découverte à l'âge adulte de façon fortuite ou par une infection respiratoire récidivante. Son diagnostic est établi par la tomodensitométrie thoracique avec injection du produit de contraste, et son traitement est essentiellement conservateur. Nous rapportons un cas d'hypoplasie pulmonaire gauche révélée chez un jeune de 20 ans par une infection respiratoire récidivante. PMID:24396564

  4. VizieR Online Data Catalog: RM AGNs accretion rates and BH masses (Du+, 2016)

    NASA Astrophysics Data System (ADS)

    Du, P.; Wang, J.-M.; Hu, C.; Ho, L. C.; Li, Y.-R.; Bai, J.-M.

    2016-05-01

    We select all AGNs with reverberation mapping (RM) data (here only broad Hβ line), which yield robust BH mass estimates needed for our analysis. All RM AGNs before 2013 are summarized by Bentz et al. (2013ApJ...767..149B). Our project to search for super-Eddington accreting massive black holes (SEAMBHs) has monitored about 25 candidates and successfully measured Hβ lags ({tau}Hβ) in 14 AGNs to date (Du et al. 2015, J/ApJ/806/22) and other five objects monitored between 2014 and 2015 (to be submitted). See section 2 for further explanations. (2 data files).

  5. Aplasie cutanée circonscrite du cuir chevelu chez un enfant rwandais: a propos d'une observation

    PubMed Central

    Ntumba-Tshitenge, Olga; Kaputu-Kalala-Malu, Célestin; Mukampunga, Caritas; Mukendi, Kavulu Mayamba

    2014-01-01

    L'aplasie cutanée circonscrite du cuir chevelu ou aplasia cutis congenita, en nomenclature latine, est une malformation rare du cuir chevelu caractérisée par une absence de ce dernier. Elle peut intéresser l’épiderme ou toute la peau. La prise en charge d'une telle malformation est assez délicate. Elle est généralement chirurgicale et le pronostic dépend en grande partie de malformations vasculaires associées. Le risque infectieux et/ou hémorragique est élevé. Cette malformation peut être isolée, ne se limitant qu’à la peau du cuir chevelu; tout comme elle peut faire partie d'un syndrome polymalformatif associant l'atteinte d'autres tissus ou organes tel qu'on peut l'observer dans le syndrome d'Adams-Oliver. Nous rapportons le cas d'un nouveau-né rwandais chez qui on a constaté, à la naissance, une absence du cuir chevelu, parcellaire, intéressant une grande partie du vertex fronto-pariétal et la région pariétale gauche. Une IRM avec séquences angiograpiques réalisée plusieurs jours plus tard, montre une agénésie de la partie frontale du sinus longitudinal supérieur. A notre connaissance, aucune observation faisant état de cette malformation n'a jamais été publiée en Afrique Centrale. PMID:25838854

  6. EPAct Transportation Regulatory Activities

    SciTech Connect

    2011-11-21

    The U.S. Department of Energy's (DOE) Vehicle Technologies Program manages several transportation regulatory activities established by the Energy Policy Act of 1992 (EPAct), as amended by the Energy Conservation Reauthorization Act of 1998, EPAct 2005, and the Energy Independence and Security Act of 2007 (EISA).

  7. Orbit to orbit transportation

    NASA Astrophysics Data System (ADS)

    Bergeron, R. P.

    1980-07-01

    Orbital transfer vehicle propulsion options for SPS include both chemical (COTV) and electrical (EOTV) options. The proposed EOTV construction method is similar to that of the SPS and, by the addition of a transmitting antenna, may serve as a demonstration or precursor satellite option. The results of the studies led to the selection of a single stage COTV for crew and priority cargo transfer. An EOTV concept is favored for cargo transfer because of the more favorable orbital burden factor over chemical systems. The gallium arsenide solar array is favored over the silicon array because of its self annealing characteristics of radiation damage encountered during multiple transitions through the Van Allen radiation belt. Transportation system operations are depicted. A heavy lift launch vehicle (HLLV) delivers cargo and propellants to LEO, which are transferred to a dedicated EOTV by means of an intraorbit transfer vehicle (IOTV) for subsequent transfer to GEO. The space shuttle is used for crew transfer from Earth to LEO. At the LEO base, the crew module is removed from the shuttle cargo bay and mated to a COTV for transfer to GEO. Upon arrival at GEO, the SPS construction cargo is transferred from the EOTV to the SPS construction base by IOTV. Crew consumables and resupply propellants are transported to GEO by the EOTV. Transportation requirements are dominated by the vast quantity of materials to be transported to LEO and GEO.

  8. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Affonso Lourenco; Evren Ozbayoglu; Lei Zhou

    2002-01-30

    This is the second quarterly progress report for Year 3 of the ACTS project. It includes a review of progress made in: (1) Flow Loop development and (2) research tasks during the period of time between Oct 1, 2001 and Dec. 31, 2001. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Collection System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), and Foam properties while transporting cuttings. (Task 12), (f) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  9. Neoclassical transport in stellarators

    SciTech Connect

    Ho, D.D.M.; Kulsrud, R.M.

    1985-09-01

    The stellarator neoclassical transport due to particles trapped in local helical wells is calculated in the low-collisionality regime using a systematic expansion. The behavior of electron transport is found to be the same over a wide range of energies, but the behavior of ion transport for low energy ions is found to be different than that for high energy ions. Furthermore, the electron fluxes do not vary with the change in the radial ambipolar electric field nearly as much as do the ion fluxes. Thus, the particle diffusion is controlled by the electrons. A nonradial ambipolar electric field is induced by ion drift. This electric field enhances the transport by about 15 to 20%. A convenient graphical method that allows one to determine the magnitude of the radial ambipolar field for machines with different parameters is presented. Numerical examples show that electron energy confinement time is comparable to the ion energy confinement time for all the different size stellarators studied. Although the neoclassical losses are large, it is shown that ignition can be achieved in a reasonably sized stellarator reactor. Finally, from the standpoint of reactor economics, the confinement scaling law shows that in order to increase n tau, it is better to increase the aspect ratio than the overall dimensions of the reactor.

  10. Slurry transport medium

    SciTech Connect

    Rosenthal, W.; Schiffman, L.

    1980-06-03

    This invention provides for an improvement in slurry transport systems, especially coal slurry lines. Instead of the usual use of fresh water resources which, in some geographic areas, are scarce for slurry transport, concentrated brine is used which is prepared from abundant salt water resources. Because of the higher density of this concentrated brine, it is a superior carrier of pulverized material. It diminishes the separation and settling tendency of slurry components during transport and particularly during shutdown. Other advantages in the use of concentrated brine include: freezing point depression which permits ease of transport during winter and at lower temperatures; dust suppression of stored coal; avoidance of spontaneous combustion of stored coal; inhibit freeze packing of dewatered pipeline coal; and diminished extent of corrosion in ferrous metal pipelines as compared to that which might occur with lower concentration brines. Important in the economy of the process is that the concentrated brine can be recycled. An inexpensive method for producing the concentrated brine is given.

  11. Mixing and Transport.

    ERIC Educational Resources Information Center

    Ditmars, John D.

    1978-01-01

    Presents a literature review of longitudinal dispersion, mixing and transport in streams, rivers, lakes, reservoirs, estuaries, and oceans. This review covers also: (1) fluid-solid mixtures and (2) oil spill behavior. A list of 189 references published in 1976 and 1977 is presented. (HM)

  12. TRANSPORTATION LONG AGO.

    ERIC Educational Resources Information Center

    George Washington Univ., Washington, DC.

    THIS HISTORICAL REVIEW OF TRANSPORTATION REPRESENTS AN EXPERIMENTAL BOOKLET OF ILLUSTRATIONS AND SINGLE TEXT FOR USE BY TEACHERS TO STIMULATE INTEREST IN READING AND IN RELATED MECHANICAL SUBJECT MATTER AREAS. IT AIMS TO HELP YOUNG PEOPLE LEARN BASIC PRINCIPLES AND CONCEPTS OF MECHANICS AND TECHNOLOGY. PHOTOGRAPHS AND ILLUSTRATIONS, SELECTED FROM…

  13. Charging up Transportation.

    ERIC Educational Resources Information Center

    Vail, Kathleen R.

    1994-01-01

    In Antelope Valley, California, a regional transportation consortium, cooperatively run by six adjacent school districts, is operating an electric-powered school bus as a pilot project. Although the prototype bus cost nearly six times more than a traditional school bus, lower operating and maintenance expenses and safety factors appeal to many…

  14. Training Guide: Road Transport.

    ERIC Educational Resources Information Center

    Kogan Page, Ltd., London (England).

    The third in a series of guides to British industrial training, this publication begins with a survey of training issues and tasks confronting the Road Transport Industry Training Board (RTITB). This is followed by information on RTITB policies and provisions; RTITB members, officers, and committees; apprenticeships and other training schemes;…

  15. School Transportation: Administrator's Handbook

    ERIC Educational Resources Information Center

    Missouri Department of Elementary and Secondary Education, 2008

    2008-01-01

    Pupil transportation is an essential part of the overall school program, which requires constant supervision and direction. Perhaps no other phase of the school program is more closely observed by the public or has a greater tendency to mold public opinion about the schools than the school bus system. The success of any school district pupil…

  16. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Evren Ozbayoglu; Lei Zhou

    2002-04-30

    This is the third quarterly progress report for Year 3 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between Jan. 1, 2002 and Mar. 31, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Separation System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 9b): ''Study of Foam Flow Behavior Under EPET Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings. (Task 12), and Viscosity of Foam under EPET (Task 9b); (f) Development of a Safety program for the ACTS Flow Loop, progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S); and (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  17. Technology transfer-transportation

    NASA Technical Reports Server (NTRS)

    Anyos, T.; Lizak, R.; Wilhelm, J.; Hirschberg, K.

    1974-01-01

    The application of aerospace technology to the solution of urban public transportation problems is considered. Data are given on highway and railway systems with particular attention given to safety devices, fuel economy, and measures for profiling railways and highways. The development of streamlined truck bodies, to reduce air drag, and efficient brake systems for light trucks and other vehicles was also dealt with.

  18. Transportation and platforms perspective

    NASA Technical Reports Server (NTRS)

    Bennett, Gary L.

    1992-01-01

    The topics covered are presented in viewgraph form and include the following: Office of Aeronautics and Space Technology; space research and technology (R&T); space R&T mission statement; Space R&T program development; R&T strategy; Office of Space Science and Applications (OSSA) technology needs; transportation technology; and space platforms technology.

  19. Platelet transport in microchannels

    NASA Astrophysics Data System (ADS)

    Reyssat, Mathilde; Le Goff, Anne; Blin, Antoine; Pujos, Justine; Magniez, Aurélie; Baruch, Dominique

    2013-11-01

    Blood platelets are small enucleated cells responsible for the arrest of bleeding. These cells have the ability to tether and translocate on injured vascular endothelium, thanks to a specific interaction between a receptor of their membrane and a protein expressed by the cells composing the inner wall of the vessel, the von Willebrand factor (VWF). Others cells have such abilities of rolling. Leucocytes, for example, translocate on surface due to a specific interaction between selectin molecules and their respective glycoprotein ligands. These kinds of cells present two modes of transport: they can either be advected by the flux, or translocate on surfaces due to specific ligand-receptor interactions. Our work consists first in studying experimentally the transport of platelets along a microchannel and then in modeling this particular cell transport. Due to these two modes of transport along a channel, platelets adhering to the surface are not equally distributed along the channel axis. We describe the evolution of the density of platelets with time and distance.

  20. Child Transportation Safety Tips.

    ERIC Educational Resources Information Center

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    This document presents nine tips regarding safe infant and child transportation, each tip explained in one to two pages. The tips are as follows: (1) quick safety seat checkup; (2) where should your child ride? (3) how to protect your new baby in the car; (4) what safety seat to use for a big baby or toddler? (5) how should preschool and school…

  1. Technology transfer-transportation

    NASA Technical Reports Server (NTRS)

    Anyos, T.; Lizak, R.; Wilhelm, J.

    1974-01-01

    Problems in the public transportation industry and refining methods for decreasing the time gap between the development and the marketing of new technology are considered. Eight NASA innovations are either being adapted for use on highways, railways, or rapid transit, or are already entering the marketplace. Chronologies for three of these programs are provided.

  2. Alternate Transportation Routes

    ERIC Educational Resources Information Center

    Vogel, Carl

    2009-01-01

    Since last school year, the St. Lucie County (Florida) Public Schools reduced the number of buses it operates from 399 to 362, despite opening two new schools. Add in some other smart changes in policy, and the district lowered its annual transportation costs by more than $3 million over last year. Saving $3 million a year does not come easily,…

  3. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira

    2000-10-30

    This is the first quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between July 14, 2000 and September 30, 2000. This report presents information on the following specific tasks: (a) Progress in Advanced Cuttings Transport Facility design and development (Task 2), (b) Progress on research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (c) Progress on research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (d) Progress on research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (e) Progress on research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Initiate research on project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Progress on instrumentation tasks to measure: Cuttings concentration and distribution (Tasks 11), and Foam properties (Task 12), (h) Initiate a comprehensive safety review of all flow-loop components and operational procedures. Since the previous Task 1 has been completed, we will now designate this new task as: (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  4. A corporate supersonic transport

    NASA Technical Reports Server (NTRS)

    Greene, Randall; Seebass, Richard

    1996-01-01

    This talk address the market and technology for a corporate supersonic transport. It describes a candidate configuration. There seems to be a sufficient market for such an aircraft, even if restricted to supersonic operation over water. The candidate configuration's sonic boom overpressure may be small enough to allow overland operation as well.

  5. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Lei Zhou; Zhu Chen; Crystal Redden; Aimee Washington

    2003-01-30

    This is the second quarterly progress report for Year-4 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between October 1, 2002 and December 30, 2002. This report presents a review of progress on the following specific tasks. (a) Design and development of an Advanced Cuttings Transport Facility Task 3: Addition of a Cuttings Injection/Separation System, Task 4: Addition of a Pipe Rotation System. (b) New research project (Task 9b): ''Development of a Foam Generator/Viscometer for Elevated Pressure and Elevated Temperature (EPET) Conditions''. (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions''. (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings. (Task 12), and Viscosity of Foam under EPET (Task 9b). (f) New Research project (Task 13): ''Study of Cuttings Transport with Foam under Elevated Pressure and Temperature Conditions''. (g) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (h) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  6. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Evren Ozbayoglu; Lei Zhou

    2002-07-30

    This is the fourth quarterly progress report for Year-3 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between April 1, 2002 and June 30, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Separation System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)''; (c) Research project (Task 9b): ''Study of Foam Flow Behavior Under EPET Conditions''; (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions''; (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings. (Task 12), and Viscosity of Foam under EPET (Task 9b); (f) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S); (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  7. Transportation: Destination Mars

    NASA Technical Reports Server (NTRS)

    Eoff, Bill

    1998-01-01

    As the agency space transportation lead center, Marshall Space Flight Center has been conducting transportation assessments for future robotic and human Mars missions to identify critical technologies. Five human Mars options are currently under assessment with each option including all transportation requirements from Earth to Mars and return. The primary difference for each option is the propulsion source from Earth to Mars. In case any of the options require heavy launch capability that is not currently projected as available, an in-house study has been initiated to determine the most cost effective means of providing such launch capability. This assessment is only considering launch architectures that support the overall human Mars mission cost goal of $25B. The guidelines for the launch capability study included delivery of 80 metric ton (176 KLB) payloads, 25 feet diameter x 92 feet long, to 220 nmi orbits at 28.5 degrees. The launch vehicle concept of the study was designated "Magnum" to differentiate from prior heavy launch vehicle assessments. This assessment along with the assessment of options for all transportation phases of a Mars mission are on-going.

  8. School Planning Safe Transporting.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Education, Trenton. Bureau of Pupil Transportation.

    Prepared for boards of education and municipal planning authorities, school site selection is related to school bus safety. Consideration of direction and density of traffic flow, street crossings, curbing, drainage, road width, parking areas, number of pupils and personnel, number of buses, method of transportation, schedules and extra-curricular…

  9. TRANSPORTATION TODAY AND TOMORROW.

    ERIC Educational Resources Information Center

    DAILEY, JOHN T.; NEYMAN, CLINTON A., JR.

    THIS READING TEXT WAS DEVELOPED IN A CURRICULUM PROJECT, DESCRIBED IN VT 004 454, ALONG WITH OTHER MATERIALS TO STIMULATE READING ABOUT MECHANICAL AND TECHNOLOGICAL TOPICS AND TO TEACH BASIC VOCATIONAL TALENTS. THE ORGANIZING THEME OF THE TEXT IS TRANSPORTATION AND POWER. MAJOR PORTIONS OF THE BOOK ARE DEVOTED TO PICTURES AND EASY-READING…

  10. Pipeline transport of biomass.

    PubMed

    Kumar, Amit; Cameron, Jay B; Flynn, Peter C

    2004-01-01

    The cost of transporting wood chips by truck and by pipeline as a water slurry was determined. In a practical application of field delivery by truck of biomass to a pipeline inlet, the pipeline will only be economical at large capacity ( >0.5 million dry t/yr for a one-way pipeline, and >1.25 million dry t/yr for a two-way pipeline that returns the carrier fluid to the pipeline inlet), and at medium to long distances ( >75 km [one-way] and >470 km [two-way] at a capacity of 2 million dry t/yr). Mixed hardwood and softwood chips in western Canada rise in moisture level from about 50% to 67% when transported in water; the loss in lower heating value (LHV) would preclude the use of water slurry pipelines for direct combustion applications. The same chips, when transported in a heavy gas oil, take up as much as 50% oil by weight and result in a fuel that is >30% oil on mass basis and is about two-thirds oil on a thermal basis. Uptake of water by straw during slurry transport is so extreme that it has effectively no LHV. Pipeline-delivered biomass could be used in processes that do not produce contained water as a vapor, such as supercritical water gasification.

  11. High speed civil transport

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This report discusses the design and marketability of a next generation supersonic transport. Apogee Aeronautics Corporation has designated its High Speed Civil Transport (HSCT): Supercruiser HS-8. Since the beginning of the Concorde era, the general consensus has been that the proper time for the introduction of a next generation Supersonic Transport (SST) would depend upon the technical advances made in the areas of propulsion (reduction in emissions) and material composites (stronger, lighter materials). It is believed by many in the aerospace industry that these beforementioned technical advances lie on the horizon. With this being the case, this is the proper time to begin the design phase for the next generation HSCT. The design objective for a HSCT was to develop an aircraft that would be capable of transporting at least 250 passengers with baggage at a distance of 5500 nmi. The supersonic Mach number is currently unspecified. In addition, the design had to be marketable, cost effective, and certifiable. To achieve this goal, technical advances in the current SST's must be made, especially in the areas of aerodynamics and propulsion. As a result of these required aerodynamic advances, several different supersonic design concepts were reviewed.

  12. Space station mobile transporter

    NASA Technical Reports Server (NTRS)

    Renshall, James; Marks, Geoff W.; Young, Grant L.

    1988-01-01

    The first quarter of the next century will see an operational space station that will provide a permanently manned base for satellite servicing, multiple strategic scientific and commercial payload deployment, and Orbital Maneuvering Vehicle/Orbital Transfer Vehicle (OMV/OTV) retrieval replenishment and deployment. The space station, as conceived, is constructed in orbit and will be maintained in orbit. The construction, servicing, maintenance and deployment tasks, when coupled with the size of the station, dictate that some form of transportation and manipulation device be conceived. The Transporter described will work in conjunction with the Orbiter and an Assembly Work Platform (AWP) to construct the Work Station. The Transporter will also work in conjunction with the Mobile Remote Servicer to service and install payloads, retrieve, service and deploy satellites, and service and maintain the station itself. The Transporter involved in station construction when mounted on the AWP and later supporting a maintenance or inspection task with the Mobile Remote Servicer and the Flight Telerobotic Servicer is shown.

  13. Cutting Transportation Costs.

    ERIC Educational Resources Information Center

    Lewis, Barbara

    1982-01-01

    Beginning on the front cover, this article tells how school districts are reducing their transportation costs. Particularly effective measures include the use of computers for bus maintenance and scheduling, school board ownership of buses, and the conversion of gasoline-powered buses to alternative fuels. (Author/MLF)

  14. High speed civil transport

    NASA Technical Reports Server (NTRS)

    Mcknight, R. L.

    1992-01-01

    The design requirements of the High Speed Civil Transport (HSCT) are discussed. The following design concerns are presented: (1) environmental impact (emissions and noise); (2) critical components (the high temperature combustor and the lightweight exhaust nozzle); and (3) advanced materials (high temperature ceramic matrix composites (CMC's)/intermetallic matrix composites (IMC's)/metal matrix composites (MMC's)).

  15. Urban Mass Transportation.

    ERIC Educational Resources Information Center

    Mervine, K. E.

    This bibliography is part of a series of Environmental Resource Packets prepared under a grant from EXXON Education Foundation. The most authoritative and accessible references in the urban transportation field are reviewed. The authors, publisher, point of view, level, and summary are given for each reference. The references are categorized…

  16. Storing and transporting energy

    DOEpatents

    McClaine, Andrew W.; Brown, Kenneth

    2010-09-07

    Among other things, hydrogen is released from water at a first location using energy from a first energy source; the released hydrogen is stored in a metal hydride slurry; and the metal hydride slurry is transported to a second location remote from the first location.

  17. A lunar transportation system

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Due to large amounts of oxygen required for space travel, a method of mining, transporting, and storing this oxygen in space would facilitate further space exploration. The following project deals specifically with the methods for transporting liquid oxygen from the lunar surface to the Lunar Orbit (LO) space station, and then to the Lower Earth Orbit (LEO) space station. Two vehicles were designed for operation between the LEO and LO space stations. The first of these vehicles is an aerobraked design vehicle. The Aerobrake Orbital Transfer Vehicle (OTV) is capable of transporting 5000 lbm of payload to LO while returning to LEO with 60,000 lbm of liquid oxygen, and thus meet mission requirements. The second vehicle can deliver 18,000 lbm of payload to LO and is capable of bringing 60,000 lbm of liquid oxygen back to LEO. A lunar landing vehicle was also designed for operation between LO and the established moon base. The use of an electromagnetic railgun as a method for launching the lunar lander was also investigated. The feasibility of the railgun is doubtful at this time. A system of spheres was also designed for proper storing and transporting of the liquid oxygen. The system assumes a safe means for transferring the liquid oxygen from tank to tank is operational. A sophisticated life support system was developed for both the OTV and the lunar lander. This system focuses on such factors as the vehicle environment, waste management, water requirements, food requirements, and oxygen requirements.

  18. Artificial oxygen transport protein

    DOEpatents

    Dutton, P. Leslie

    2014-09-30

    This invention provides heme-containing peptides capable of binding molecular oxygen at room temperature. These compounds may be useful in the absorption of molecular oxygen from molecular oxygen-containing atmospheres. Also included in the invention are methods for treating an oxygen transport deficiency in a mammal.

  19. Draft Transportation Institutional Plan

    SciTech Connect

    Not Available

    1985-09-01

    The Department of Energy recognizes that the success of its program to develop and implement a national system for nuclear waste management and disposal depends on broad-based public understanding and acceptance. While each program element has its particular sensitivity, the transportation of the waste may potentially affect the greatest number of people, and accordingly is highly visible and potentially issue-laden. Therefore, the Office of Civilian Radioactive Waste Management has developed this Transportation Institutional Plan to lay the foundation for interaction among all interested parties for the purpose of identifying and resolving issues of concern. The Plan is divided into four chapters. Chapter 1 provides bachground information and discusses the purpose of the Plan and the policy guidance for establishing the transportation system. Chapter 2 introduces the major participants who must interact to build both the system itself and the consensus philosophy that is essential for effective operations. Chapter 3 suggests mechanisms for interaction that will ensure wide participation in program planning and implementation. And, finally, Chapter 4 suggests a framework for managing and resolving the issues related to development and operation of the transportation system. A list of acronyms and a glossary are included for the reader's convenience. The Plan's appendices provide supporting material to assist the reader in understanding the roles of the involved institutions. 4 figs., 1 tab.

  20. Saturated Zone Colloid Transport

    SciTech Connect

    H. S. Viswanathan

    2004-10-07

    This scientific analysis provides retardation factors for colloids transporting in the saturated zone (SZ) and the unsaturated zone (UZ). These retardation factors represent the reversible chemical and physical filtration of colloids in the SZ. The value of the colloid retardation factor, R{sub col} is dependent on several factors, such as colloid size, colloid type, and geochemical conditions (e.g., pH, Eh, and ionic strength). These factors are folded into the distributions of R{sub col} that have been developed from field and experimental data collected under varying geochemical conditions with different colloid types and sizes. Attachment rate constants, k{sub att}, and detachment rate constants, k{sub det}, of colloids to the fracture surface have been measured for the fractured volcanics, and separate R{sub col} uncertainty distributions have been developed for attachment and detachment to clastic material and mineral grains in the alluvium. Radionuclides such as plutonium and americium sorb mostly (90 to 99 percent) irreversibly to colloids (BSC 2004 [DIRS 170025], Section 6.3.3.2). The colloid retardation factors developed in this analysis are needed to simulate the transport of radionuclides that are irreversibly sorbed onto colloids; this transport is discussed in the model report ''Site-Scale Saturated Zone Transport'' (BSC 2004 [DIRS 170036]). Although it is not exclusive to any particular radionuclide release scenario, this scientific analysis especially addresses those scenarios pertaining to evidence from waste-degradation experiments, which indicate that plutonium and americium may be irreversibly attached to colloids for the time scales of interest. A section of this report will also discuss the validity of using microspheres as analogs to colloids in some of the lab and field experiments used to obtain the colloid retardation factors. In addition, a small fraction of colloids travels with the groundwater without any significant retardation

  1. Liposome reconstitution and transport assay for recombinant transporters.

    PubMed

    Johnson, Zachary Lee; Lee, Seok-Yong

    2015-01-01

    Secondary active transporters are responsible for the cellular uptake of many biologically important molecules, including neurotransmitters, nutrients, and drugs. Because of their physiological and clinical importance, a method for assessing their transport activity in vitro is necessary to gain a better understanding of how these transporters function at the molecular level. In this chapter, we describe a protocol for reconstituting the concentrative nucleoside transporter from Vibrio cholerae into proteoliposomes. We then describe a radiolabeled substrate uptake assay that can be used to functionally characterize the transporter. These methods are relatively common and can be applied to other secondary active transporters, with or without some modification.

  2. Cancer du sein au Cameroun, profil histo-épidémiologique: à propos de 3044 cas

    PubMed Central

    Engbang, Jean Paul Ndamba; Essome, Henri; Koh, Valère Mve; Simo, Godefroy; Essam, Jean Daniel Sime; Mouelle, Albert Sone; Essame, Jean Louis Oyono

    2015-01-01

    Décrire les caractéristiques épidémiologiques et histo-pathologiques des tumeurs malignes du sein au Cameroun. Il s'agissait d'une étude rétrospective descriptive portant sur les tumeurs malignes du sein, colligées, dans les registres des différents laboratoires d'Anatomie Pathologique publiques et privés repartis dans cinq régions (centre, littoral, Ouest, Nord-ouest, Sud-ouest), pendant une période de 10 ans (2004-2013). Les paramètres étudiés étaient la fréquence, l’âge, le sexe, la localisation, le type et le grade histologique, et les récepteurs hormonaux. Un total de 3044 cas de cancers du sein a été recensé, soit une fréquence annuelle de 304,4 cas en moyenne. Le sexe féminin était le plus représenté avec 2971 cas (97,60%) et les hommes avec 73 cas (2,40%), soit un sexe ratio (H/F) de 0,02. L’âge moyen des patients était de 46±15,87 ans, avec des extrêmes de 13 et 95 ans. Selon la localisation, le sein gauche était atteint dans 1244 cas (52%) et le sein droit dans 1115 cas (47%). Au plan histologique, on retrouvait essentiellement des carcinomes avec 96,50% des cas, des sarcomes 1,39%, des lymphomes 1,07% et la maladie de Paget du mamelon, 1,03%. Les tumeurs épithéliales étaient infiltrantes dans 2049 cas (84,46%), avec une prédominance du carcinome canalaire infiltrant (1870 cas) et non infiltrantes dans 377 cas (15,54%). Le grade histo-pronostic de SBR avait révélé une prédominance du grade II dans 66% des cas. Les cancers du sein restent une pathologie fréquente au Cameroun et atteignent principalement la population féminine en âge de procréer. Ils sont caractérisés par la prédominance du carcinome canalaire infiltrant. PMID:26523182

  3. (Cent ans après...) Hipparcos, une troisième dimension pour la Carte du Ciel

    NASA Astrophysics Data System (ADS)

    Arenou, F.; Turon, C.

    2008-06-01

    At the beginning of the Carte du Ciel project, a few stellar parallaxes were known only. At the end of the project, Hipparcos/Tycho takes the lead of the study of the dimension of the nearby universe. Hipparcos is - and Gaia will also be - a revenge of astrometry as an irreplaceable tool for astrophysics; they are also, with Tycho-2, a one hundred years bridge with the Carte du Ciel. After describing the context in astrometry, we comment in details the content, use, and success of these projects.

  4. Sirénomélie (Mermaid Syndrome): description du premier cas Congolais et revue de la literature

    PubMed Central

    Lubala, Toni Kasole; Mukuku, Olivier; Mutombo, Augustin Mulangu

    2014-01-01

    La sirénomélie est une forme rare de dysgénésie caudale généralement incompatible avec la vie du fait des malformations rénales graves qui y sont associées. En Afrique, elle est associée à des considérations mystico-religieuses et à la sorcellerie et expose la famille à une stigmatisation violente. Son étiologie est encore très controversée. A notre connaissance, il s'agit du premier cas congolais rapporté dans la littérature. PMID:25120875

  5. Surgical Position, Cause of Extracranial Internal Carotid Artery Dissection, Presenting as Pourfour Du Petit Syndrome: Case Report and Literature Review.

    PubMed

    Villalba Martinez, Gloria; Navalpotro Gomez, Irene; Serrano Perez, Laura; Gonzalez Ortiz, Sofia; Fernández-Candil, Juan L; Steinhauer, Eva Giralt

    2015-01-01

    Dissection of the internal carotid artery is a rare cause of stroke overall, but causes 22% of strokes in younger patients. A common clinical presentation is as Claude Bernard Horner syndrome. We report a craniotomy with 30 degrees rotation of the neck (standard position) in a patient with no major risk factors for carotid dissection, who showed a Pourfour du Petit syndrome due to a dissection of the internal carotid artery. To the best of our knowledge, this is the first reported case in which a common surgical position causes an internal carotid artery dissection in a patient without relevant risk factors. The presentation with Pourfour du Petit syndrome is extremely unusual.

  6. Visually Exploring Transportation Schedules.

    PubMed

    Palomo, Cesar; Guo, Zhan; Silva, Cláudio T; Freire, Juliana

    2016-01-01

    Public transportation schedules are designed by agencies to optimize service quality under multiple constraints. However, real service usually deviates from the plan. Therefore, transportation analysts need to identify, compare and explain both eventual and systemic performance issues that must be addressed so that better timetables can be created. The purely statistical tools commonly used by analysts pose many difficulties due to the large number of attributes at trip- and station-level for planned and real service. Also challenging is the need for models at multiple scales to search for patterns at different times and stations, since analysts do not know exactly where or when relevant patterns might emerge and need to compute statistical summaries for multiple attributes at different granularities. To aid in this analysis, we worked in close collaboration with a transportation expert to design TR-EX, a visual exploration tool developed to identify, inspect and compare spatio-temporal patterns for planned and real transportation service. TR-EX combines two new visual encodings inspired by Marey's Train Schedule: Trips Explorer for trip-level analysis of frequency, deviation and speed; and Stops Explorer for station-level study of delay, wait time, reliability and performance deficiencies such as bunching. To tackle overplotting and to provide a robust representation for a large numbers of trips and stops at multiple scales, the system supports variable kernel bandwidths to achieve the level of detail required by users for different tasks. We justify our design decisions based on specific analysis needs of transportation analysts. We provide anecdotal evidence of the efficacy of TR-EX through a series of case studies that explore NYC subway service, which illustrate how TR-EX can be used to confirm hypotheses and derive new insights through visual exploration.

  7. Merging a Terrain-Based Parameter and Snow Particle Counter Data for the Assessment of Snow Redistribution in the Col du Lac Blanc Area

    NASA Astrophysics Data System (ADS)

    Schön, Peter; Prokop, Alexander; Naaim-Bouvet, Florence; Vionnet, Vincent; Guyomarc'h, Gilbert; Heiser, Micha; Nishimura, Kouichi

    2015-04-01

    Wind and the associated snow drift are dominating factors determining the snow distribution and accumulation in alpine areas, resulting in a high spatial variability of snow depth that is difficult to evaluate and quantify. The terrain-based parameter Sx characterizes the degree of shelter or exposure of a grid point provided by the upwind terrain, without the computational complexity of numerical wind field models. The parameter has shown to qualitatively predict snow redistribution with good reproduction of spatial patterns. It does not, however, provide a quantitative estimate of changes in snow depths. The objective of our research was to introduce a new parameter to quantify changes in snow depths in our research area, the Col du Lac Blanc in the French Alps. The area is at an elevation of 2700 m and particularly suited for our study due to its consistently bi-modal wind directions. Our work focused on two pronounced, approximately 10 m high terrain breaks, and we worked with 1 m resolution digital snow surface models (DSM). The DSM and measured changes in snow depths were obtained with high-accuracy terrestrial laser scan (TLS) measurements. First we calculated the terrain-based parameter Sx on a digital snow surface model and correlated Sx with measured changes in snow-depths (Δ SH). Results showed that Δ SH can be approximated by Δ SHestimated = α * Sx, where α is a newly introduced parameter. The parameter α has shown to be linked to the amount of snow deposited influenced by blowing snow flux. At the Col du Lac Blanc test side, blowing snow flux is recorded with snow particle counters (SPC). Snow flux is the number of drifting snow particles per time and area. Hence, the SPC provide data about the duration and intensity of drifting snow events, two important factors not accounted for by the terrain parameter Sx. We analyse how the SPC snow flux data can be used to estimate the magnitude of the new variable parameter α . To simulate the development

  8. Structural diversity of ABC transporters

    PubMed Central

    ter Beek, Josy; Guskov, Albert

    2014-01-01

    ATP-binding cassette (ABC) transporters form a large superfamily of ATP-dependent protein complexes that mediate transport of a vast array of substrates across membranes. The 14 currently available structures of ABC transporters have greatly advanced insight into the transport mechanism and revealed a tremendous structural diversity. Whereas the domains that hydrolyze ATP are structurally related in all ABC transporters, the membrane-embedded domains, where the substrates are translocated, adopt four different unrelated folds. Here, we review the structural characteristics of ABC transporters and discuss the implications of this structural diversity for mechanistic diversity. PMID:24638992

  9. Transporter taxonomy - a comparison of different transport protein classification schemes.

    PubMed

    Viereck, Michael; Gaulton, Anna; Digles, Daniela; Ecker, Gerhard F

    2014-06-01

    Currently, there are more than 800 well characterized human membrane transport proteins (including channels and transporters) and there are estimates that about 10% (approx. 2000) of all human genes are related to transport. Membrane transport proteins are of interest as potential drug targets, for drug delivery, and as a cause of side effects and drug–drug interactions. In light of the development of Open PHACTS, which provides an open pharmacological space, we analyzed selected membrane transport protein classification schemes (Transporter Classification Database, ChEMBL, IUPHAR/BPS Guide to Pharmacology, and Gene Ontology) for their ability to serve as a basis for pharmacology driven protein classification. A comparison of these membrane transport protein classification schemes by using a set of clinically relevant transporters as use-case reveals the strengths and weaknesses of the different taxonomy approaches.

  10. [The image of animal magnetism in fictional literature: the cases of Poe, Doyle and Du Maurier].

    PubMed

    Bonet Safont, Juan Marcos

    2014-01-01

    In this article, we focus on the social image of the phenomenon known as mesmerism, or animal magnetism, through analysis of the works: The Facts in the Case of M. Valdemar (1845) by Edgar Allan Poe, The Great Keinplatz Experiment (1885) by Conan Doyle and Trilby (1894) by George Du Maurier. We describe the stereotype of the mesmerist and the uses of mesmerism observed. We pay attention to the spaces and actors of the mesmeric transcript presented in the stories. We consider the reception of these stories by the public and the relationship of the authors with mesmeric and hypnotic knowledge. Nowadays, academic researchers in the discipline of psychology publish articles and books on popular myths about hypnosis in attempts to depict the distorted images related to this phenomenon. This distorted image of the hypnotic process and the hypnotist derives from "circus" hypnotism shows (stage hypnosis), the cinema, television and fictional literature. Works of fiction represent a unique and invaluable source of information, ideas, speculations, concerns and opportunities around animal magnetism and hypnosis, and the exploration and analysis of this literature is an essential chapter in any historical study of this topic. We see how the literary use of mesmerism by Poe, Doyle and Du Maurier is not chance or peripheral, with all three being intellectually interested in and stimulated by these ideas.

  11. [The image of animal magnetism in fictional literature: the cases of Poe, Doyle and Du Maurier].

    PubMed

    Bonet Safont, Juan Marcos

    2014-01-01

    In this article, we focus on the social image of the phenomenon known as mesmerism, or animal magnetism, through analysis of the works: The Facts in the Case of M. Valdemar (1845) by Edgar Allan Poe, The Great Keinplatz Experiment (1885) by Conan Doyle and Trilby (1894) by George Du Maurier. We describe the stereotype of the mesmerist and the uses of mesmerism observed. We pay attention to the spaces and actors of the mesmeric transcript presented in the stories. We consider the reception of these stories by the public and the relationship of the authors with mesmeric and hypnotic knowledge. Nowadays, academic researchers in the discipline of psychology publish articles and books on popular myths about hypnosis in attempts to depict the distorted images related to this phenomenon. This distorted image of the hypnotic process and the hypnotist derives from "circus" hypnotism shows (stage hypnosis), the cinema, television and fictional literature. Works of fiction represent a unique and invaluable source of information, ideas, speculations, concerns and opportunities around animal magnetism and hypnosis, and the exploration and analysis of this literature is an essential chapter in any historical study of this topic. We see how the literary use of mesmerism by Poe, Doyle and Du Maurier is not chance or peripheral, with all three being intellectually interested in and stimulated by these ideas. PMID:25481969

  12. [The image of animal magnetism in fictional literature: the cases of Poe, Doyle and Du Maurier].

    PubMed

    Bonet Safont, Juan Marcos

    2014-01-01

    In this article, we focus on the social image of the phenomenon known as mesmerism, or animal magnetism, through analysis of the works: The Facts in the Case of M. Valdemar (1845) by Edgar Allan Poe, The Great Keinplatz Experiment (1885) by Conan Doyle and Trilby (1894) by George Du Maurier. We describe the stereotype of the mesmerist and the uses of mesmerism observed. We pay attention to the spaces and actors of the mesmeric transcript presented in the stories. We consider the reception of these stories by the public and the relationship of the authors with mesmeric and hypnotic knowledge. Nowadays, academic researchers in the discipline of psychology publish articles and books on popular myths about hypnosis in attempts to depict the distorted images related to this phenomenon. This distorted image of the hypnotic process and the hypnotist derives from "circus" hypnotism shows (stage hypnosis), the cinema, television and fictional literature. Works of fiction represent a unique and invaluable source of information, ideas, speculations, concerns and opportunities around animal magnetism and hypnosis, and the exploration and analysis of this literature is an essential chapter in any historical study of this topic. We see how the literary use of mesmerism by Poe, Doyle and Du Maurier is not chance or peripheral, with all three being intellectually interested in and stimulated by these ideas. PMID:25508821

  13. Phonatory and phonetic characteristics of prelinguistic vocal development in cri du chat syndrome.

    PubMed

    Sohner, L; Mitchell, P

    1991-02-01

    A longitudinal case study of a child with cri du chat syndrome was undertaken to provide descriptive data on early phonatory and phonetic development in comfort state vocalizations. Vocal samples collected when the child was between 8 and 26 months of age were analyzed using perceptual and acoustic methods. Results indicated that the high vocal fundamental frequently documented in cries of infants with cri du chat syndrome was also a characteristic of comfort state vocalizations of this child. An analysis of intonation patterns indicated there was a predominance of falling intonation contours and limited interutterance variation of fundamental frequency. Phonetic development was quite delayed, with major acquisitions in babbling showing marked delay relative to chronological age. Acquisition of the first spoken word had not occurred by the age of twenty-six months. Results suggest that significant cognitive and/or motor delays may have an influence on the integrity of early vocal development, which calls into question the notion that babbling development proceeds relatively independently of other developmental domains.

  14. The Reality of Neandertal Symbolic Behavior at the Grotte du Renne, Arcy-sur-Cure, France

    PubMed Central

    Caron, François; d'Errico, Francesco; Del Moral, Pierre; Santos, Frédéric; Zilhão, João

    2011-01-01

    Background The question of whether symbolically mediated behavior is exclusive to modern humans or shared with anatomically archaic populations such as the Neandertals is hotly debated. At the Grotte du Renne, Arcy-sur-Cure, France, the Châtelperronian levels contain Neandertal remains and large numbers of personal ornaments, decorated bone tools and colorants, but it has been suggested that this association reflects intrusion of the symbolic artifacts from the overlying Protoaurignacian and/or of the Neandertal remains from the underlying Mousterian. Methodology/Principal Findings We tested these hypotheses against the horizontal and vertical distributions of the various categories of diagnostic finds and statistically assessed the probability that the Châtelperronian levels are of mixed composition. Our results reject that the associations result from large or small scale, localized or generalized post-depositional displacement, and they imply that incomplete sample decontamination is the parsimonious explanation for the stratigraphic anomalies seen in the radiocarbon dating of the sequence. Conclusions/Significance The symbolic artifacts in the Châtelperronian of the Grotte du Renne are indeed Neandertal material culture. PMID:21738702

  15. Curiethérapie dans le traitement palliatif du cancer de l’œsophage

    PubMed Central

    Toulba, Ahmedou; Bakkali, Hanae; Boutayeb, Salwa; Kebdani, Tayeb; Ahid, Samir; Benjaafar, Noureddine

    2015-01-01

    Les patients atteints du cancer de l’œsophage ont souvent une maladie localement avancée, la dysphagie est le symptôme majeur chez la plupart de ces patients, plusieurs modalités thérapeutiques ont été utilisées pour améliorer cette dysphagie. Le but de ce travail est d’étudier l'efficacité et la tolérance de la curiethérapie haut débit de dose (HDR) endo-luminale dans le traitement palliatif des cancers de l’œsophage inopérable. Sur une période de 15 ans, l’étude a inclus les patients atteints de cancer de l’œsophage inopérable et/ou métastatique avec une dysphagie, sans extension à l'hypopharynx ou a la trachée et qui ont bénéficié d'une curiethérapie HDR avec ou sans radiothérapie externe à visée palliative. Au total 46 patients ont été inclus dans l’étude, 58,7% étaient des hommes, 42,2% avaient une dysphagie grade 2 et 37,8% étaient aphagiques, 78,6% des patients étaient performance satus PS 2, l'amaigrissement à été trouvé chez 81,4%, la localisation de la tumeur était surtout au niveau du tiers moyen et inférieur dans 97,8%, la hauteur médiane de la tumeur était de 7 cm (5,5-9), le carcinome épidermoïde était le type histologique le plus fréquent chez 31 patients (70,5%). Après un médiane de suivi de 5 mois, l'amélioration de la dysphagie a été retrouvée chez 76% des malades (p1]. L′incidence la plus élevée est observée dans certains pays notamment en Asie et en Afrique, et l′incidence dans les pays développés occidentaux est en augmentation [2]. Selon le registre du cancer de Rabat 2006-2008, le cancer de l’œsophage est rare et constitue 1,5% de tous les cancers chez l'homme [3]. Le taux de survie globale à 5 ans est de 8%, avec 80% des décès liés à l’évolution locale de la maladie [4]. Pour la minorité des patients avec une maladie localisée, le traitement par radiochimiothérapie concomitante avec ou sans chirurgie permet une amélioration de la survie [5]. Plus de 50

  16. Prise en Charge du Syndrome de Lyell ou Necrolyse Epidermique Toxique

    PubMed Central

    Siah, S.; Baite, A.; Bakkali, H.; Atmani, M.; Ababou, K.; Ihrai, H.

    2009-01-01

    Summary Le syndrome de Lyell ou nécrolyse épidermique toxique (NET) est une pathologie très grave des dermatoses bulleuses d'étiologie médicamenteuse. Il se caractérise par une nécrose aiguë de l'épiderme sur toute la hauteur du corps muqueux. L'aspect clinique de la NET est celui d'une brûlure étendue du deuxième degré profond. A ce tableau s'associent constamment des lésions muqueuses et une atteinte multiviscérale qui aggrave le pronostic. Nous rapportons deux cas de NET qui illustrent l'importance d'une prise en charge précoce et multidisciplinaire de ces patients atteints au sein d'un service de réanimation des brûlés, dont les fondements reposent sur l'asepsie rigoureuse, l'apport hydroélectrolytique et nutritionnel, la prévention de l'infection et son traitement par une antibiothérapie adaptée, et un nursing et des soins locaux. L'efficacité supposée des immunoglobulines intraveineuses ne repose que sur des cas isolés et il n'y a pas encore d'études randomisées. PMID:21991170

  17. O'Connell effect in early-type contact binaries: du Boo and AG Vir

    NASA Astrophysics Data System (ADS)

    Pribulla, T.; Vaňko, M.; Chochol, D.; Hambálek, Ľ.; Parimucha, Š.

    2011-07-01

    The paper presents new photoelectric observations of the eclipsing binary systems DU Boo and AG Vir. The systems are somewhat similar - both are A-type contact binaries with the maximum following the primary minimum being the brighter one. This light curve asymmetry is extremely temporally stable. The phase dependence of the color indices is unexpectedly small for the observed amplitude of the O'Connell effect, amounting to about 0.1 mag in the optical wavelength range which indicates a very large heated area with a temperature contrast of {Δ T ≈} 1000-1500 K. The broadening functions (BFs) of the systems do not show any dark solar-type photospheric spots. On the other hand, there are significant differences of BFs between the quadratures (surprisingly similar in both systems) indicative of stream of matter or bright region causing additional emission seen between the components around the phase 0.25. Absolute parameters of the components slightly depend on the adopted model. Long orbital period of both contact binaries combined with late spectral type indicate that the primary components of either of the systems (but particularly in case of DU Boo) already evolved off the main sequence. Based on spectroscopic data from the David Dunlap Observatory, University of Toronto

  18. Wetlands of Argonne National Laboratory-East DuPage County, Illinois

    SciTech Connect

    Van Lonkhuyzen, R.A.; LaGory, K.E.

    1994-03-01

    Jurisdictional wetlands of the Argonne National Laboratory-East (ANL-E) site in DuPage County, Illinois, were delineated in the summer and autumn of 1993 in accordance with the 1987 US Army Corps of Engineers methodology. Potential wetland sites with an area greater than 500 m{sup 2} (0.05 ha [0.124 acre]) were identified for delineation on the basis of aerial photographs, the DuPage County soil survey, and reconnaissance-level field studies. To qualify as a jurisdictional wetland, an area had to support a predominance of hydrophytic vegetation as well as have hydric soil and wetland hydrology. Thirty-five individual jurisdictional wetlands were delineated at ANL-E, totaling 180,604 m{sup 2} (18.1 ha [44.6 acres]). These wetlands were digitized onto the ANL-E site map for use in project planning. Characteristics of each wetland are presented -- including size, dominant plant species and their indicator status, hydrologic characteristics (including water source), and soil characteristics.

  19. History of planetary science. The Pic du Midi Planetary Observation Project : 1941-1971

    NASA Astrophysics Data System (ADS)

    Dollfus, Audouin

    1998-08-01

    When, in 1941, Bernard Lyot attempted to observe planet Mars at Pic du Midi, he experienced unusual viewing conditions. He realized that this circumstance was not at all exceptional for the Pic but representative of a remarkable property of the high altitude site. He decided to design, and put into operation at the top of the mountain a refractor, 60 cm in diameter, specially conceived for high angular resolution. With such a capability, Henry Camichel, Jean Focas and Audouin Dollfus initiated a deep and long-term research project based upon planetary surface exploration, with high telescopic magnification. Visual analysis, photographic work, double image micrometry, photometric and polarimetric sensing were the most frequently used techniques and they were combined. Full exploitation of all these approaches required 30 years of continuous work, essentially coordinated by Observatoire de Paris at Meudon. The project was completed almost at the time when spacecraft missions within the Solar System began to replace telescopic work for planetary physics. At this time, the Pic du Midi work have released new basic physical properties about planets and satellites. Knowledge was acquired and fundamental problems settled, which are reviewed.

  20. Lymphome malin non Hodgkinien primitif du larynx: à propos d'un cas

    PubMed Central

    Elmazghi, Abderrahman; Elkacemi, Hanan; Lalya, Issam; Zaidi, Hanan; Harmouch, Amal; Kanouni, Lamia; Kebdani, Taieb; Hassouni, Khalid; Benjaafar, Noureddine; Elgueddari, Brahim

    2011-01-01

    Le lymphome malin non hodgkinien (LMNH) primitif laryngé est une entité rare qui représente moins de 1% des cancers du larynx. Nous rapportons un nouveau cas, chez un homme de 24 ans qui avait présenté une dysphonie et une dysphagie d'installations progressives. La laryngoscopie a révélé une lésion bourgeonnante de la bande ventriculaire gauche. L'histologie a objectivé un lymphome T, CD3 positif, qui a bien évolué après traitement par quatre cures de CHOP (cyclophosphamide, doxorubicine, vincristine, et prednisone), suivies d'une radiothérapie sur le larynx et le médiastin supérieur à la dose totale de 40Gy. Malgré sa rareté relative, cette pathologie de diagnostic difficile, nécessite une vigilance particulière et devrait être gérée selon les tendances actuelles du traitement pour les LMNH ganglionnaires. PMID:22355427

  1. Le contrôle des infections au cabinet du pédiatre

    PubMed Central

    2008-01-01

    RÉSUMÉ La transmission des infections au cabinet du pédiatre est de plus en plus préoccupante. Le présent document expose les voies de transmission des infections et les principes sous-jacents aux mesures actuelles pour contrôler les infections. Pour prévenir les infections, il faut bien concevoir le cabinet et adopter des politiques administratives et de triage convenables, de même que des pratiques de base pour les soins de tous les patients (p. ex., hygiène des mains, port de gants, de masques, de lunettes de protection et d’une blouse d’hôpital pour des interventions précises; nettoyage, désinfection et stérilisation convenables des surfaces et du matériel, y compris les jouets, et techniques d’asepsie en cas d’interventions effractives) et des précautions additionnelles en cas d’infections précises. Le personnel doit avoir reçu les vaccins pertinents, et les personnes infectées doivent respecter les politiques de restriction au travail.

  2. Syndrome de Gougerot-Sjögren primitif du sujet âgé: caractéristiques cliniques et immunologiques

    PubMed Central

    Chebbi, Wafa; Ben Salem, Wafa; Klii, Rim; Kessomtini, Wassia; Jerbi, Saida; Sfar, Mohamed Habib

    2015-01-01

    Les objectifs de notre étude est d’étudier les caractéristiques cliniques et immunologiques du syndrome de Gougerot Sjogren primitif (SGSp) du sujet âgé et les comparer à une population témoin plus jeune. Nous avons analysé rétrospectivement les dossiers de 60 patients atteints de SGSp consécutifs, suivis au service de Médecine interne du CHU Taher Sfar de Mahdia, en Tunisie, durant une période de 7 ans (janvier 2007 à décembre 2013). Les patients avec SGSp étaient classés en deux groupes selon l’âge de début de la maladie: groupe de sujets âgés (≥ 65 ans) et groupe de sujets jeunes (<65 ans). Chez 18 patients (30%), le SGSp a débuté après 65 ans. Il s'agissait de 17 femmes (94,5%) et un homme (5,5%). L’âge moyen du début du SGSp était de 70,5 ans ±3,1. Le délai moyen du diagnostic était de 38,6 mois ±26,8. Les manifestations glandulaires étaient constantes. La comparaison entre le groupe du SGSp du sujet âgé et celui du sujet jeune montrait que le délai moyen du diagnostic du SGSp était significativement plus long chez les sujets âgés. Les manifestations pulmonaires étaient significativement plus fréquentes chez les sujets âgés. En revanche, les fréquences des anticorps antinucléaires, anti-SSA et anti-SSB étaient significativement plus élevées chez les sujets jeunes. Bien que le SGSp soit une maladie typique d'adultes d’âge moyen, les cliniciens ne devraient pas ignorer que cette maladie peut être diagnostiquée aussi chez les patients âgés. Notre étude montre que l’âge du début avancé influence le profil clinique et immunologique du SGSp. PMID:25995805

  3. Mass Transport within Soils

    SciTech Connect

    McKone, Thomas E.

    2009-03-01

    Contaminants in soil can impact human health and the environment through a complex web of interactions. Soils exist where the atmosphere, hydrosphere, geosphere, and biosphere converge. Soil is the thin outer zone of the earth's crust that supports rooted plants and is the product of climate and living organisms acting on rock. A true soil is a mixture of air, water, mineral, and organic components. The relative proportions of these components determine the value of the soil for agricultural and for other human uses. These proportions also determine, to a large extent, how a substance added to soil is transported and/or transformed within the soil (Spositio, 2004). In mass-balance models, soil compartments play a major role, functioning both as reservoirs and as the principal media for transport among air, vegetation, surface water, deeper soil, and ground water (Mackay, 2001). Quantifying the mass transport of chemicals within soil and between soil and atmosphere is important for understanding the role soil plays in controlling fate, transport, and exposure to multimedia pollutants. Soils are characteristically heterogeneous. A trench dug into soil typically reveals several horizontal layers having different colors and textures. As illustrated in Figure 1, these multiple layers are often divided into three major horizons: (1) the A horizon, which encompasses the root zone and contains a high concentration of organic matter; (2) the B horizon, which is unsaturated, lies below the roots of most plants, and contains a much lower organic carbon content; and (3) the C horizon, which is the unsaturated zone of weathered parent rock consisting of bedrock, alluvial material, glacial material, and/or soil of an earlier geological period. Below these three horizons lies the saturated zone - a zone that encompasses the area below ground surface in which all interconnected openings within the geologic media are completely filled with water. Similarly to the unsaturated zone

  4. Transport mechanism of a glutamate transporter homologue GltPh

    PubMed Central

    Ji, Yurui; Postis, Vincent L.G.; Wang, Yingying; Bartlam, Mark; Goldman, Adrian

    2016-01-01

    Glutamate transporters are responsible for uptake of the neurotransmitter glutamate in mammalian central nervous systems. Their archaeal homologue GltPh, an aspartate transporter isolated from Pyrococcus horikoshii, has been the focus of extensive studies through crystallography, MD simulations and single-molecule FRET (smFRET). Here, we summarize the recent research progress on GltPh, in the hope of gaining some insights into the transport mechanism of this aspartate transporter. PMID:27284058

  5. Geology and ground-water resources of Fond du Lac County, Wisconsin

    USGS Publications Warehouse

    Newport, Thomas G.

    1962-01-01

    The principal water-bearing rocks underlying Fond du Lac County, Wis., are sandstones of Cambrian and Ordovician age and dolomite of Silurian age. Other aquifers include dolomite of Ordovician age and sand. and gravel of Quaternary age. Crystalline rocks of Precambrian age, which underlie all the water-bearing formations, form a practically impermeable basement complex and yield little or no water to wells. Ground water is the source of all public and most private and industrial water supplies in the county. The municipalities and industries obtain water chiefly from wells that penetrate the sandstones of Cambrian and Ordorician age. The Platteville formation and Galena dolomite of Ordovician age and the Niagara dolomite of Silurian age supply water to most domestic and stock wells and to a few industrial wells. Several buried valleys in the bedrock surface contain water-bearing deposits of sand and gravel. The source of the ground water in Fond du Lac County is local precipitation. Recharge to the water-bearing beds occurs in most of the county but is greatest where the bedrock formations are near the surface. Ground water is discharged by seeps and springs, by evaporation and transpiration, and by wells. Ground-water levels in wells fluctuate in response to recharge and to natural discharge and pumping. In areas not affected by pumping, water levels generally decline through the summer months because of natural discharge and lack of recharge, recover slightly in the fall after the first killing frost, decline during the winter, and recover in the spring when recharge is greatest. In areas of heavy pumping, the water levels are lowest in late summer and highest in late winter. Water levels in wells in the Fond du Lac area were about 5 to 50 feet above the land surface in 1885, but they had declined to as low as 185 feet below the land surface by 1957. Coefficients of transmissibility and storage of the sandstones of Cambrian and Ordovician age were determined by

  6. L’effet du yoga chez les patients atteints de cancer

    PubMed Central

    Côté, Andréanne; Daneault, Serge

    2012-01-01

    Résumé Objectif Déterminer si le yoga thérapeutique améliore la qualité de vie de patients atteints de cancer. Sources des données Recherche effectuée avec la base de données MEDLINE (1950–2010) en utilisant les mots-clés yoga, cancer et quality of life. Sélection des études Priorité accordée aux études cliniques randomisées contrôlées évaluant l’effet du yoga sur différents symptômes susceptibles de se présenter chez des patients atteints de cancer en Amérique du Nord. Synthèse Quatre études cliniques randomisées contrôlées ont d’abord été analysées, puis 2 études sans groupe-contrôle. Trois études réalisées en Inde et au Proche-Orient ont également apporté des éléments intéressants au plan méthodologique. Les interventions proposées comprenaient des séances de yoga d’une durée et d’une fréquence variables. Les paramètres mesurés variaient également d’une étude à l’autre. Plusieurs symptômes ont connu des améliorations significatives avec le yoga (meilleure qualité du sommeil, diminution des symptômes anxieux ou dépressifs, amélioration du bien-être spirituel, etc.). Il a aussi semblé que la qualité de vie, dans sa globalité ou dans certaines de ses composantes spécifiques, s’améliorait. Conclusion La variété des effets bénéfiques produits, l’absence d’effet secondaire et le rapport coût-bénéfice avantageux du yoga thérapeutique en fait une intervention intéressante à suggérer par les médecins de famille aux patients atteints de cancer. Certaines lacunes méthodologiques ont pu diminuer la puissance statistique des études présentées, à commencer par la taille restreinte des échantillons et par l’assiduité variable des patients soumis à l’intervention. Il est également possible que les échelles de mesure utilisées ne convenaient pas à ce type de situation et de clientèle pour qu’en soit dégagé un effet significatif. Toutefois, les commentaires

  7. Soil Transport Implement

    NASA Technical Reports Server (NTRS)

    Dixon, William; Fan, William; Lloyd, Joey; Pham, Nam-Anh; Stevens, Michael

    1988-01-01

    The design of the Soil Transport Implement (STI) for SKITTER is presented. The purpose of STI is to provide a protective layer of lunar soil for the lunar modules. The objective is to cover the lunar module with a layer of soil approximately two meters thick within a two week period. The amount of soil required to cover the module is roughly 77 dump truck loads or three million earth pounds. A spinning disk is employed to accomplish its task. STI is an autonomous, teleoperated system. The design incorporates the latest advances in composite materials and high strength, light weight alloys to achieve a high strength to weight ratio. The preliminary design should only be used to assess the feasibility of employing a spinning wheel as a soil transport implement. A mathematical model of the spinning wheel was used to evaluate the performance of this design.

  8. Transportation Systems Evaluation

    NASA Technical Reports Server (NTRS)

    Fanning, M. L.; Michelson, R. A.

    1972-01-01

    A methodology for the analysis of transportation systems consisting of five major interacting elements is reported. The analysis begins with the causes of travel demand: geographic, economic, and demographic characteristics as well as attitudes toward travel. Through the analysis, the interaction of these factors with the physical and economic characteristics of the transportation system is determined. The result is an evaluation of the system from the point of view of both passenger and operator. The methodology is applicable to the intraurban transit systems as well as major airlines. Applications of the technique to analysis of a PRT system and a study of intraurban air travel are given. In the discussion several unique models or techniques are mentioned: i.e., passenger preference modeling, an integrated intraurban transit model, and a series of models to perform airline analysis.

  9. Arsenite transport in plants.

    PubMed

    Ali, Waqar; Isayenkov, Stanislav V; Zhao, Fang-Jie; Maathuis, Frans J M

    2009-07-01

    Arsenic is a metalloid which is toxic to living organisms. Natural occurrence of arsenic and human activities have led to widespread contamination in many areas of the world, exposing a large section of the human population to potential arsenic poisoning. Arsenic intake can occur through consumption of contaminated crops and it is therefore important to understand the mechanisms of transport, metabolism and tolerance that plants display in response to arsenic. Plants are mainly exposed to the inorganic forms of arsenic, arsenate and arsenite. Recently, significant progress has been made in the identification and characterisation of proteins responsible for movement of arsenite into and within plants. Aquaporins of the NIP (nodulin26-like intrinsic protein) subfamily were shown to transport arsenite in planta and in heterologous systems. In this review, we will evaluate the implications of these new findings and assess how this may help in developing safer and more tolerant crops.

  10. Renewable transportation technologies

    SciTech Connect

    Bull, S.R.

    1995-12-31

    The need for alternative and renewable transportation fuels continues to be high on the nation`s agenda. Substituting these fuels for petroleum can reduce dependence on foreign oil imports, improve air quality, and mitigate greenhouse gases. Renewable fuels offer the same advantages as nonrenewable alternative fuels, and, in addition, provide an inexhaustible supply. The largest potential for significant quantities of liquid renewable fuels is from the production of biofuels from cellulosic biomass such as wastes and energy crops. Advanced vehicles will provide dramatic fuel efficiency improvements and will likely have electric drive systems. An evolution of vehicles is expected to occur, beginning with an electric vehicle that fills niche markets in the near term, to hybrid vehicles by the year 2000, to fuel cell vehicles after the year 2005. With the combination of renewable fuels and high efficiency, advanced vehicles can move the nation toward a sustainable transportation system.

  11. Saturated Zone Colloid Transport

    SciTech Connect

    H. Viswanathan; P. Reimus

    2003-09-05

    Colloid retardation is influenced by the attachment and detachment of colloids from immobile surfaces. This analysis demonstrates the development of parameters necessary to estimate attachment and detachment of colloids and, hence, retardation in both fractured tuff and porous alluvium. Field and experimental data specific to fractured tuff are used for the analysis of colloid retardation in fractured tuff. Experimental data specific to colloid transport in alluvial material from Yucca Mountain as well as bacteriophage field studies in alluvial material, which are thought to be good analogs for colloid transport, are used to estimate attachment and detachment of colloids in the alluvial material. There are no alternative scientific approaches or technical methods for calculating these retardation factors.

  12. Transportation and the marketplace

    SciTech Connect

    Soeoet, S.

    1996-12-31

    In the Chicago six-county metropolitan area, the number of registered vehicles grew by over 800,000 vehicles in the 1980s; by contrast the population increased by just over 150,000 during the same time. This ratio of growth in automobiles versus population (five to one) has contributed to overall increases in travel, congestion and energy use. The objective of this report is to examine how and why this has occurred and what we might expect in the near future to address the growing traffic problems and energy use. Specifically, the focus is on energy use by household vehicles and other forms of passenger travel. Data on population trends, gasoline prices, commuting and transit use, and transportation energy use are presented and interpreted. Intelligent transportation systems and decreased single vehicle emissions are briefly described as methods to decrease congestion and pollution. 9 figs., 2 tabs.

  13. High speed civil transport

    NASA Technical Reports Server (NTRS)

    Bogardus, Scott; Loper, Brent; Nauman, Chris; Page, Jeff; Parris, Rusty; Steinbach, Greg

    1990-01-01

    The design process of the High Speed Civil Transport (HSCT) combines existing technology with the expectation of future technology to create a Mach 3.0 transport. The HSCT was designed to have a range in excess of 6000 nautical miles and carry up to 300 passengers. This range will allow the HSCT to service the economically expanding Pacific Basin region. Effort was made in the design to enable the aircraft to use conventional airports with standard 12,000 foot runways. With a takeoff thrust of 250,000 pounds, the four supersonic through-flow engines will accelerate the HSCT to a cruise speed of Mach 3.0. The 679,000 pound (at takeoff) HSCT is designed to cruise at an altitude of 70,000 feet, flying above most atmospheric disturbances.

  14. FAA Smoke Transport Code

    2006-10-27

    FAA Smoke Transport Code, a physics-based Computational Fluid Dynamics tool, which couples heat, mass, and momentum transfer, has been developed to provide information on smoke transport in cargo compartments with various geometries and flight conditions. The software package contains a graphical user interface for specification of geometry and boundary conditions, analysis module for solving the governing equations, and a post-processing tool. The current code was produced by making substantial improvements and additions to a codemore » obtained from a university. The original code was able to compute steady, uniform, isothermal turbulent pressurization. In addition, a preprocessor and postprocessor were added to arrive at the current software package.« less

  15. Cellular iron transport.

    PubMed

    Garrick, Michael D; Garrick, Laura M

    2009-05-01

    Iron has a split personality as an essential nutrient that also has the potential to generate reactive oxygen species. We discuss how different cell types within specific tissues manage this schizophrenia. The emphasis in enterocytes is on regulating the body's supply of iron by regulating transport into the blood stream. In developing red blood cells, adaptations in transport manage the body's highest flux of iron. Hepatocytes buffer the body's stock of iron. Macrophage recycle the iron from effete red cells among other iron management tasks. Pneumocytes provide a barrier to prevent illicit entry that, when at risk of breaching, leads to a need to handle the dangers in a fashion essentially shared with macrophage. We also discuss or introduce cell types including renal cells, neurons, other brain cells, and more where our ignorance, currently still vast, needs to be removed by future research. PMID:19344751

  16. Mars transportation system

    NASA Technical Reports Server (NTRS)

    Garrard, William; Vano, Andrew; Rutherford, Dave

    1992-01-01

    The University of Minnesota Advanced Space Design Program has developed a sample Mars exploration scenario. The purpose of the design project is to enhance NASA and university interaction, to provide fresh ideas to NASA, and to provide real world design problems to engineering students. The Mars Transportation System in this paper is designed to transport a crew of six astronauts to the Martian surface and return them to Low Earth Orbit (LEO) starting in the year 2016. The proposed vehicle features such advanced technologies as nuclear propulsion, nuclear power generation, and aerobraking. Three missions are planned. Orbital trajectories are of the conjunction class with an inbound Venus swingby providing a 60-day surface stay at Mars and an average total trip time of 520 days.

  17. Nonlinear chiral transport phenomena

    NASA Astrophysics Data System (ADS)

    Chen, Jiunn-Wei; Ishii, Takeaki; Pu, Shi; Yamamoto, Naoki

    2016-06-01

    We study the nonlinear responses of relativistic chiral matter to the external fields such as the electric field E , gradients of temperature and chemical potential, ∇T and ∇μ . Using the kinetic theory with Berry curvature corrections under the relaxation time approximation, we compute the transport coefficients of possible new electric currents that are forbidden in usual chirally symmetric matter but are allowed in chirally asymmetric matter by parity. In particular, we find a new type of electric current proportional to ∇μ ×E due to the interplay between the effects of the Berry curvature and collisions. We also derive an analog of the "Wiedemann-Franz" law specific for anomalous nonlinear transport in relativistic chiral matter.

  18. Fuel cell water transport

    DOEpatents

    Vanderborgh, Nicholas E.; Hedstrom, James C.

    1990-01-01

    The moisture content and temperature of hydrogen and oxygen gases is regulated throughout traverse of the gases in a fuel cell incorporating a solid polymer membrane. At least one of the gases traverses a first flow field adjacent the solid polymer membrane, where chemical reactions occur to generate an electrical current. A second flow field is located sequential with the first flow field and incorporates a membrane for effective water transport. A control fluid is then circulated adjacent the second membrane on the face opposite the fuel cell gas wherein moisture is either transported from the control fluid to humidify a fuel gas, e.g., hydrogen, or to the control fluid to prevent excess water buildup in the oxidizer gas, e.g., oxygen. Evaporation of water into the control gas and the control gas temperature act to control the fuel cell gas temperatures throughout the traverse of the fuel cell by the gases.

  19. Rail transportation update

    SciTech Connect

    Buchsbaum, L.

    2009-01-15

    Record western coal shipments and lucrative export traffic lead America's railroad to their fourth most profitable year in history. But with the coal boom going bust, higher rates, and a new administration and congress, what sort of transportation year can coal mines and shippers expect in 2009? The article gives the opinions of company executives and discusses findings of the recent so-called Christenson Report which investigated growing railroad market power. 1 ref., 1 fig.

  20. Heat transport system

    DOEpatents

    Pierce, Bill L.

    1978-01-01

    A heat transport system of small size which can be operated in any orientation consists of a coolant loop containing a vaporizable liquid as working fluid and includes in series a vaporizer, a condenser and two one-way valves and a pressurizer connected to the loop between the two valves. The pressurizer may be divided into two chambers by a flexible diaphragm, an inert gas in one chamber acting as a pneumatic spring for the system.

  1. Space Transportation Main Engine

    NASA Technical Reports Server (NTRS)

    Monk, Jan C.

    1992-01-01

    The topics are presented in viewgraph form and include the following: Space Transportation Main Engine (STME) definition, design philosophy, robust design, maximum design condition, casting vs. machined and welded forgings, operability considerations, high reliability design philosophy, engine reliability enhancement, low cost design philosophy, engine systems requirements, STME schematic, fuel turbopump, liquid oxygen turbopump, main injector, and gas generator. The major engine components of the STME and the Space Shuttle Main Engine are compared.

  2. Saltation transport on Mars.

    PubMed

    Parteli, Eric J R; Herrmann, Hans J

    2007-05-11

    We present the first calculation of saltation transport and dune formation on Mars and compare it to real dunes. We find that the rate at which grains are entrained into saltation on Mars is 1 order of magnitude higher than on Earth. With this fundamental novel ingredient, we reproduce the size and different shapes of Mars dunes, and give an estimate for the wind velocity on Mars.

  3. Transportation Systems Center

    SciTech Connect

    Greer, G.S.

    1992-07-01

    The Transportation Systems Center at Sandia Laboratory performs research, development, and implementation of technologies that enhance the safe movement of people, goods, and information. Our focus is on systems engineering. However, we realize that to understand the puzzle, you must also understand the pieces. This brochure describes some of the activities currently underway at the Center and presents the breadth and depth of our capabilities. Please contact the noted, individuals for more, information.

  4. Technology transfer: Transportation

    NASA Technical Reports Server (NTRS)

    Anyos, T.; Christy, L.; Lizak, R.; Wilhelm, J.

    1978-01-01

    The successful application of aerospace technology to problems related to highways and rail and rapid transit systems is described with emphasis on the use of corrosion resistant paints, fire retardant materials, and law enforcement. Possible areas for the use of spinoff from NASA technology by the California State Department of Corrections are identified. These include drug detection, security and warning systems, and the transportation and storage of food. A communication system for emergency services is also described.

  5. Space Shuttle Debris Transport

    NASA Technical Reports Server (NTRS)

    Gomez, Reynaldo J., III

    2010-01-01

    This slide presentation reviews the assessment of debris damage to the Space Shuttle, and the use of computation to assist in the space shuttle applications. The presentation reviews the sources of debris, a mechanism for determining the probability of damaging debris impacting the shuttle, tools used, eliminating potential damaging debris sources, the use of computation to assess while inflight damage, and a chart showing the applications that have been used on increasingly powerful computers simulate the shuttle and the debris transport.

  6. Epidémiologie et prise en charge des infections du per-partum à la maternité du centre hospitalier départemental de l'Ouémé-Plateau au Bénin

    PubMed Central

    Saizonou, Jacques; Ouédraogo, Laurent; Paraiso, Moussiliou Noël; Ayélo, Paul; Kpozèhouen, Alphonse; Daraté, René; Traoré, Esther

    2014-01-01

    Introduction La présente étude avait pour objectif de mesurer l'ampleur des infections du per-partum à la maternité du Centre Hospitalier Départemental de l'Ouémé-Plateau d'analyser les conditions de survenue et de prise en charge dans la perspective de l'amélioration des soins et services maternels et néonataux. Méthodes Une étude descriptive et analytique a été conduite de Août 2009 à Février 2010 et a impliqué 110 mères victimes d'infections du per-partum; elles ont été soumises à un questionnaire durant tout leur séjour hospitalier; des observations des pratiques de prise en charge des prestataires de soins ont été menées et des registres et autres supports de données sanitaires ont été exploités. L'analyse des données a été effectuée à l'aide du logiciel Epi Info 6.4 dans sa version française. Résultats L'incidence des infections du per-partum était de 5,9 pour 100 accouchements (110/ 1875); les types d'infections les plus incriminés étaient les endométrites (27,3%), les chorioamniotites (18,2%), les infections du site opératoire (12,7%) et les infections urinaires (2,7%). Les examens cliniques ont été relativement acceptables. En revanche, les examens biologiques ont été très insuffisants expliquant l'imprécision importante au niveau des diagnostics. L'antibiothérapie a été instaurée systématiquement. Le taux de mortinaissance était de 25,6% et les enfants de petit poids représentaient 23,2%. Conclusion L'incidence des infections du per-partum dans la présente étude était assez élevée. Des efforts de préventions et de dépistage de ces infections sont nécessaire afin d'améliorer la qualité des soins PMID:25120854

  7. Transportation of medical isotopes

    SciTech Connect

    Nielsen, D.L.

    1997-11-19

    A Draft Technical Information Document (HNF-1855) is being prepared to evaluate proposed interim tritium and medical isotope production at the Fast Flux Test Facility (FFTF). This assessment examines the potential health and safety impacts of transportation operations associated with the production of medical isotopes. Incident-free and accidental impacts are assessed using bounding source terms for the shipment of nonradiological target materials to the Hanford Site, the shipment of irradiated targets from the FFTF to the 325 Building, and the shipment of medical isotope products from the 325 Building to medical distributors. The health and safety consequences to workers and the public from the incident-free transportation of targets and isotope products would be within acceptable levels. For transportation accidents, risks to works and the public also would be within acceptable levels. This assessment is based on best information available at this time. As the medical isotope program matures, this analysis will be revised, if necessary, to support development of a final revision to the Technical Information Document.

  8. Multiscale thermal transport.

    SciTech Connect

    Graham, Samuel Jr.; Wong, C. C.; Piekos, Edward Stanley

    2004-02-01

    A concurrent computational and experimental investigation of thermal transport is performed with the goal of improving understanding of, and predictive capability for, thermal transport in microdevices. The computational component involves Monte Carlo simulation of phonon transport. In these simulations, all acoustic modes are included and their properties are drawn from a realistic dispersion relation. Phonon-phonon and phonon-boundary scattering events are treated independently. A new set of phonon-phonon scattering coefficients are proposed that reflect the elimination of assumptions present in earlier analytical work from the simulation. The experimental component involves steady-state measurement of thermal conductivity on silicon films as thin as 340nm at a range of temperatures. Agreement between the experiment and simulation on single-crystal silicon thin films is excellent, Agreement for polycrystalline films is promising, but significant work remains to be done before predictions can be made confidently. Knowledge gained from these efforts was used to construct improved semiclassical models with the goal of representing microscale effects in existing macroscale codes in a computationally efficient manner.

  9. Ozone transport commission developments

    SciTech Connect

    Joyce, K.M.

    1995-08-01

    On September 27, 1994, the states of the Ozone Transport Commission (OTC) signed an important memorandum of understanding (MOU) agreeing to develop a regional strategy for controlling stationary sources of nitrogen oxide emissions. Specifically, the states of the Ozone Transport Region, OTR, agreed to propose regulations for the control of NOx emissions from boilers and other indirect heat exchangers with a maximum gross heat input rate of at least 250 million BTU per hour. The Ozone Transport Region was divided into Inner, Outer and Northern Zones. States in the Outer Zone agreed to reduce NOx emissions by 55%. States in the Inner Zone agreed to reduce NOx emissions 65%. Facilities in both zones have the option to emit NOx at a rate no greater than 0.2 pounds per million Btu by May 1, 1999. This option provides fairness for the gas-fired plants which already have relatively low NOx emissions. Additionally, States in the Inner and Outer Zones agreed to reduce their NOx emissions by 75% or to emit NOx at a rate no greater than 0.15 pounds per million BTU by May 1, 2003. The Northern Zone States agree to reduce their rate of NOx emissions by 55% from base year levels by May 1, 2003, or to emit NOx at a rate no greater than 0.2 pounds per million BTU. As part of this MOU, States also agreed to develop a regionwide trading mechanism to provide a cost-effective mechanism for implementing the reductions.

  10. Space Transportation Systems Technologies

    NASA Technical Reports Server (NTRS)

    Laue, Jay H.

    2001-01-01

    This document is the final report by the Science Applications International Corporation (SAIC) on contracted support provided to the National Aeronautics and Space Administration (NASA) under Contract NAS8-99060, 'Space Transportation Systems Technologies'. This contract, initiated by NASA's Marshall Space Flight Center (MSFC) on February 8, 1999, was focused on space systems technologies that directly support NASA's space flight goals. It was awarded as a Cost-Plus-Incentive-Fee (CPIF) contract to SAIC, following a competitive procurement via NASA Research Announcement, NRA 8-21. This NRA was specifically focused on tasks related to Reusable Launch Vehicles (RLVs). Through Task Area 3 (TA-3), "Other Related Technology" of this NRA contract, SAIC extensively supported the Space Transportation Directorate of MSFC in effectively directing, integrating, and setting its mission, operations, and safety priorities for future RLV-focused space flight. Following an initially contracted Base Year (February 8, 1999 through September 30, 1999), two option years were added to the contract. These were Option Year 1 (October 1, 1999 through September 30, 2000) and Option Year 2 (October 1, 2000 through September 30, 2001). This report overviews SAIC's accomplishments for the Base Year, Option Year 1, and Option Year 2, and summarizes the support provided by SAIC to the Space Transportation Directorate, NASA/MSFC.

  11. Surety applications in transportation

    SciTech Connect

    Matalucci, R.V.; Miyoshi, D.S.

    1998-01-01

    Infrastructure surety can make a valuable contribution to the transportation engineering industry. The lessons learned at Sandia National Laboratories in developing surety principles and technologies for the nuclear weapons complex and the nuclear power industry hold direct applications to the safety, security, and reliability of the critical infrastructure. This presentation introduces the concepts of infrastructure surety, including identification of the normal, abnormal, and malevolent threats to the transportation infrastructure. National problems are identified and examples of failures and successes in response to environmental loads and other structural and systemic vulnerabilities are presented. The infrastructure surety principles developed at Sandia National Laboratories are described. Currently available technologies including (a) three-dimensional computer-assisted drawing packages interactively combined with virtual reality systems, (b) the complex calculational and computational modeling and code-coupling capabilities associated with the new generation of supercomputers, and (c) risk-management methodologies with application to solving the national problems associated with threats to the critical transportation infrastructure are discussed.

  12. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk, Mike Volk; Lei Zhou; Zhu Chen; Crystal Redden; Aimee Washington

    2002-10-30

    This is the first quarterly progress report for Year-4 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between July 1, 2002 and Sept. 30, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility Task 3: Addition of a Cuttings Injection/Separation System, Task 4: Addition of a Pipe Rotation System, (b) New Research project (Task 9b): ''Development of a Foam Generator/Viscometer for Elevated Pressure and Elevated Temperature (EPET) Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings (Task 12), Viscosity of Foam under EPET (Task 9b). (f) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  13. Lunar transportation system

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The University Space Research Association (USRA) requested the University of Minnesota Spacecraft Design Team to design a lunar transportation infrastructure. This task was a year long design effort culminating in a complete conceptual design and presentation at Johnson Space Center. The mission objective of the design group was to design a system of vehicles to bring a habitation module, cargo, and crew to the lunar surface from LEO and return either or both crew and cargo safely to LEO while emphasizing component commonality, reusability, and cost effectiveness. During the course of the design, the lunar transportation system (LTS) has taken on many forms. The final design of the system is composed of two vehicles, a lunar transfer vehicle (LTV) and a lunar excursion vehicle (LEV). The LTV serves as an efficient orbital transfer vehicle between the earth and the moon while the LEV carries crew and cargo to the lunar surface. Presented in the report are the mission analysis, systems layout, orbital mechanics, propulsion systems, structural and thermal analysis, and crew systems, avionics, and power systems for this lunar transportation concept.

  14. Etude de facteurs de risque de la transmission du VIH de la mère à l'enfant dans la stratégie « option A » à Lubumbashi, République Démocratique du Congo

    PubMed Central

    Ngwej, Dieudonné Tshikwej; Mukuku, Olivier; Mudekereza, Rachel; Karaj, Eugénie; Odimba, Etienne Bwana Fwamba; Luboya, Oscar Numbi; Kakoma, Jean-Baptiste Sakatolo; Wembonyama, Stanis Okitotshio

    2015-01-01

    Introduction L'infection à VIH chez la femme enceinte a pour principal risque la contamination du nouveau-né. L'objectif est de déterminer le taux de transmission du VIH de la mère à l'enfant (TME) dans la ville de Lubumbashi et en évaluer les facteurs de risque. Méthodes Il s'agissait d'une étude prospective transversale à visée analytique de 157 accouchées séropositives au VIH et de leurs enfants dans 12 structures sanitaires de Lubumbashi (RDCongo) du 1er octobre 2012 au 31 décembre 2013. Les paramètres sociodémographiques, cliniques et les données relatives aux activités de PTME du VIH ont été étudiés. Les statistiques usuelles ont été utilisées pour analyser les résultats. Le seuil de significativité a été fixé à une valeur de p < 0,05. Résultats Le taux de transmission verticale du VIH était de 12,7% (20/157). Il n'y avait pas d'association significative entre les caractéristiques sociodémographiques maternelles telles que l’âge, la parité, le niveau d’étude, la profession et l’état-civil et la TME (p>0,05). La transmission verticale du VIH était significativement associée aux facteurs suivants: le stade clinique 3 de l'OMS (OR=5,18 (1,5-18,1)), la présence d'infection opportuniste (OR=8,7 (2,7-27,8)), le dépistage lors de l'accouchement (OR=6,3 (1,0-39,0)) ou au cours de l'allaitement (OR=7,1 (1,1-76,7)), au taux de CD4 maternel <350/mm3 (OR=2,9 (1,1-7,7)), l'absence de thérapie antirétrovirale chez la mère (OR=19,9 (4,8-81,9)), la naissance avant terme (OR=4,7 (1,4-16,0)), la rupture prématurée de membranes (OR=45,0 (7,4-454,6)), le faible poids de naissance (OR=5,6 (1,9-16,7)), la notion de réanimation néonatale (OR=12,4 (3,8-40,1)), la non administration de la névirapine à la naissance (OR=26,4 (7,6-92,3)) et l'alimentation mixte (OR=12,6 (1,3-115,9)). Le sexe du nourrisson et le mode d'accouchement n’étaient pas non plus associés à la transmission verticale du VIH (p>0,05). Conclusion Le taux

  15. Trafficking of Vesicular Neurotransmitter Transporters

    PubMed Central

    Fei, Hao; Grygoruk, Anna; Brooks, Elizabeth S.; Chen, Audrey; Krantz, David E.

    2010-01-01

    Vesicular neurotransmitter transporters are required for the storage of all classical and amino acid neurotransmitters in secretory vesicles. Transporter expression can influence neurotransmitter storage and release, and trafficking targets the transporters to different types of secretory vesicles. Vesicular transporters traffic to synaptic vesicles as well as large dense core vesicles, and are recycled to synaptic vesicles at the nerve terminal. Some of the intrinsic signals for these trafficking events have been defined and include a dileucine motif present in multiple transporter subtypes, an acidic cluster in the neural isoform of the vesicular monoamine transporter (VMAT2) and a polyproline motif in the vesicular glutamate transporter VGLUT1. The sorting of VMAT2 and the vesicular acetylcholine transporter (VAChT) to secretory vesicles is regulated by phosphorylation. In addition, VGLUT1 uses alternative endocytic pathways for recycling back to synaptic vesicles following exocytosis. Regulation of these sorting events has the potential to influence synaptic transmission and behavior. PMID:18507811

  16. FLUID TRANSPORT THROUGH POROUS MEDIA

    EPA Science Inventory

    Fluid transport through porous media is a relevant topic to many scientific and engineering fields. Soil scientists, civil engineers, hydrologists and hydrogeologists are concerned with the transport of water, gases and nonaqueous phase liquid contaminants through porous earth m...

  17. Nanoscale thermal transport.

    SciTech Connect

    Cahill, D. G.; Ford, W. K.; Goodson, K. E.; Mahan, G. D.; Majumdar, A.; Maris, H. J.; Merlin, R.; Phillpot, S. R.; Materials Science Division; Univ. of Illinois; Intel Corp.; Stanford Univ.; Penn State Univ.; Univ. of California at Berkeley; Brown Univ.; Univ. of Michigan

    2003-01-15

    Rapid progress in the synthesis and processing of materials with structure on nanometer length scales has created a demand for greater scientific understanding of thermal transport in nanoscale devices, individual nanostructures, and nanostructured materials. This review emphasizes developments in experiment, theory, and computation that have occurred in the past ten years and summarizes the present status of the field. Interfaces between materials become increasingly important on small length scales. The thermal conductance of many solid-solid interfaces have been studied experimentally but the range of observed interface properties is much smaller than predicted by simple theory. Classical molecular dynamics simulations are emerging as a powerful tool for calculations of thermal conductance and phonon scattering, and may provide for a lively interplay of experiment and theory in the near term. Fundamental issues remain concerning the correct definitions of temperature in nonequilibrium nanoscale systems. Modern Si microelectronics are now firmly in the nanoscale regime--experiments have demonstrated that the close proximity of interfaces and the extremely small volume of heat dissipation strongly modifies thermal transport, thereby aggravating problems of thermal management. Microelectronic devices are too large to yield to atomic-level simulation in the foreseeable future and, therefore, calculations of thermal transport must rely on solutions of the Boltzmann transport equation; microscopic phonon scattering rates needed for predictive models are, even for Si, poorly known. Low-dimensional nanostructures, such as carbon nanotubes, are predicted to have novel transport properties; the first quantitative experiments of the thermal conductivity of nanotubes have recently been achieved using microfabricated measurement systems. Nanoscale porosity decreases the permittivity of amorphous dielectrics but porosity also strongly decreases the thermal conductivity. The

  18. Social Behavior and Characteristics of Autism Spectrum Disorder in Angelman, Cornelia de Lange, and Cri du Chat Syndromes

    ERIC Educational Resources Information Center

    Moss, Joanna; Howlin, Patricia; Hastings, Richard Patrick; Beaumont, Sarah; Griffith, Gemma M.; Petty, Jane; Tunnicliffe, Penny; Yates, Rachel; Villa, Darrelle; Oliver, Chris

    2013-01-01

    We evaluated autism spectrum disorder (ASD) characteristics and social behavior in Angelman (AS; "n" ?=? 19; mean age ?=?10.35 years), Cornelia de Lange (CdLS; "n" ?=? 15; mean age ?=?12.40 years), and Cri du Chat (CdCS, also known as 5 p-syndrome; "n" ?=? 19; mean age ?=? 8.80 years) syndromes. The proportion of…

  19. Cytotoxic evaluation of different fractions of Salvia chorassanica Bunge on MCF-7 and DU 145 cell lines

    PubMed Central

    Golshan, Alireza; Amini, Elaheh; Emami, Seyed Ahmad; Asili, Javad; Jalali, Zahra; Sabouri-Rad, Sarvenaz; Sanjar-Mousavi, Naghmeh; Tayarani-Najaran, Zahra

    2016-01-01

    Because of antimicrobial, antioxidant, and anticancer potential, Salvia chorassanica Bunge (Lamiaceae) has been considered as a popular herb in Iranian traditional medicine. Previous studies have shown remarkable cytotoxic properties of the methanol, n-hexane and dichloromethane extract of S. chorassanica on human cervical cancer cells. To seek the therapeutic potentials of S. chorassanica, this study was undertaken to evaluate the cytotoxic activities of various extracts of this plant on human breast MCF-7 and prostate cancer DU 145 cells. The DU 145 cells were exposed to different concentrations of plant extracts (1-200 μg/ml). Cytotoxic activities were examined using alamarBlue® assay and apoptosis was assessed by acridine orange/propodium iodide double staining and evaluation of DNA fragmentation by flow cytometry. Our findings indicated that n-hexane and dichloromethane extracts had more cytotoxic activities against DU 145 and MCF-7 cell lines compared with other extracts (P<0.05). The acridine orange/propodium iodide staining showed apoptogenic properties of n-hexane and dichloromethane extracts which was consequently confirmed by flow cytometric histogram that exhibited an increase in sub-G1 peak in treated cells as compared with untreated cancer cell lines. Taken together, these observations demonstrated cytotoxic effects of S. chorassanica extracts on MCF-7 and DU 145 cell lines which is most likely exerted via apoptosis cell death. Therefore, further investigations on S. chorassanica extracts as potential chemotherapeutic agents are warranted. PMID:27051435

  20. Program Evaluation: Outcomes of Participation in Lac Du Bois, the French Language Village of Concordia Language Villages

    ERIC Educational Resources Information Center

    Clementi, Donna L.

    2012-01-01

    The purpose of this study was to describe perceptions of stakeholders (leadership of Concordia Language Villages, staff members and villagers of "Lac du Bois", the French Language Village of Concordia Language Villages), related to achievement of the mission statement. The research question was: How do stakeholders in "Lac du…