Dual-domain point diffraction interferometer
Naulleau, Patrick P.; Goldberg, Kenneth Alan
2000-01-01
A hybrid spatial/temporal-domain point diffraction interferometer (referred to as the dual-domain PS/PDI) that is capable of suppressing the scattered-reference-light noise that hinders the conventional PS/PDI is provided. The dual-domain PS/PDI combines the separate noise-suppression capabilities of the widely-used phase-shifting and Fourier-transform fringe pattern analysis methods. The dual-domain PS/PDI relies on both a more restrictive implementation of the image plane PS/PDI mask and a new analysis method to be applied to the interferograms generated and recorded by the modified PS/PDI. The more restrictive PS/PDI mask guarantees the elimination of spatial-frequency crosstalk between the signal and the scattered-light noise arising from scattered-reference-light interfering with the test beam. The new dual-domain analysis method is then used to eliminate scattered-light noise arising from both the scattered-reference-light interfering with the test beam and the scattered-reference-light interfering with the "true" pinhole-diffracted reference light. The dual-domain analysis method has also been demonstrated to provide performance enhancement when using the non-optimized standard PS/PDI design. The dual-domain PS/PDI is essentially a three-tiered filtering system composed of lowpass spatial-filtering the test-beam electric field using the more restrictive PS/PDI mask, bandpass spatial-filtering the individual interferogram irradiance frames making up the phase-shifting series, and bandpass temporal-filtering the phase-shifting series as a whole.
Meneses, Diogenes; Gunasekara, Dulan B.; Pichetsurnthorn, Pann; da Silva, José A. F.; de Abreu, Fabiane C.; Lunte, Susan M.
2015-01-01
In-channel amperometric detection combined with dual-channel microchip electrophoresis is evaluated using a two-electrode isolated potentiostat for reverse polarity separations. The device consists of two separate channels with the working and reference electrodes placed at identical positions relative to the end of the channel, enabling noise subtraction. In previous reports of this configuration, normal polarity and a three-electrode detection system were used. In the two-electrode detection system described here, the electrode in the reference channel acts as both the counter and reference. The effect of electrode placement in the channels on noise and detector response was investigated using nitrite, tyrosine, and hydrogen peroxide as model compounds. The effects of electrode material and size and type of reference electrode on noise and the potential shift of hydrodynamic voltammograms for the model compounds were determined. In addition, the performance of two- and three-electrode configurations using Pt and Ag/AgCl reference electrodes was compared. Although the signal was attenuated with the Pt reference, the noise was also significantly reduced. It was found that lower LOD were obtained for all three compounds with the dual-channel configuration compared to single-channel, in-channel detection. The dual-channel method was then used for the detection of nitrite in a dermal microdialysis sample obtained from a sheep following nitroglycerin administration. PMID:25256669
NASA Technical Reports Server (NTRS)
McGuire, Mary Kathleen
2011-01-01
NASA has been recently updating design reference missions for the human exploration of Mars and evaluating the technology investments required to do so. The first of these started in January 2007 and developed the Mars Design Reference Architecture 5.0 (DRA5). As part of DRA5, Thermal Protection System (TPS) sizing analysis was performed on a mid L/D rigid aeroshell undergoing a dual heat pulse (aerocapture and atmospheric entry) trajectory. The DRA5 TPS subteam determined that using traditional monolithic ablator systems would be mass expensive. They proposed a new dual-layer TPS concept utilizing an ablator atop a low thermal conductivity insulative substrate to address the issue. Using existing thermal response models for an ablator and insulative tile, preliminary hand analysis of the dual layer concept at a few key heating points indicated that the concept showed potential to reduce TPS masses and warranted further study. In FY09, the followon Entry, Descent and Landing Systems Analysis (EDL-SA) project continued by focusing on Exploration-class cargo or crewed missions requiring 10 to 50 metric tons of landed payload. The TPS subteam advanced the preliminary dual-layer TPS analysis by developing a new process and updated TPS sizing code to rapidly evaluate mass-optimized, full body sizing for a dual layer TPS that is capable of dual heat pulse performance. This paper describes the process and presents the results of the EDL-SA FY09 dual-layer TPS analyses on the rigid mid L/D aeroshell. Additionally, several trade studies were conducted with the sizing code to evaluate the impact of various design factors, assumptions and margins.
Dynamic balancing of dual-rotor system with very little rotating speed difference.
Yang, Jian; He, Shi-zheng; Wang, Le-qin
2003-01-01
Unbalanced vibration in dual-rotor rotating machinery was studied with numerical simulations and experiments. A new method is proposed to separate vibration signals of inner and outer rotors for a system with very little difference in rotating speeds. Magnitudes and phase values of unbalance defects can be obtained directly by sampling the vibration signal synchronized with reference signal. The balancing process is completed by the reciprocity influence coefficients of inner and outer rotors method. Results showed the advantage of such method for a dual-rotor system as compared with conventional balancing.
Vision sensor and dual MEMS gyroscope integrated system for attitude determination on moving base
NASA Astrophysics Data System (ADS)
Guo, Xiaoting; Sun, Changku; Wang, Peng; Huang, Lu
2018-01-01
To determine the relative attitude between the objects on a moving base and the base reference system by a MEMS (Micro-Electro-Mechanical Systems) gyroscope, the motion information of the base is redundant, which must be removed from the gyroscope. Our strategy is to add an auxiliary gyroscope attached to the reference system. The master gyroscope is to sense the total motion, and the auxiliary gyroscope is to sense the motion of the moving base. By a generalized difference method, relative attitude in a non-inertial frame can be determined by dual gyroscopes. With the vision sensor suppressing accumulative drift of the MEMS gyroscope, the vision and dual MEMS gyroscope integration system is formed. Coordinate system definitions and spatial transform are executed in order to fuse inertial and visual data from different coordinate systems together. And a nonlinear filter algorithm, Cubature Kalman filter, is used to fuse slow visual data and fast inertial data together. A practical experimental setup is built up and used to validate feasibility and effectiveness of our proposed attitude determination system in the non-inertial frame on the moving base.
Compact reflection holographic recording system with high angle multiplexing
NASA Astrophysics Data System (ADS)
Kanayasu, Mayumi; Yamada, Takehumi; Takekawa, Shunsuke; Akieda, Kensuke; Goto, Akiyo; Yamamoto, Manabu
2011-02-01
Holographic memory systems have been widely researched since 1963. However, the size of the drives required and the deterioration of reconstructed data resulting from shrinkage of the medium have made practical use of a hologram memory difficult. In light of this, we propose a novel holographic recording/reconstructing system: a dual-reference beam reflection system that is smaller than conventional systems such as the off-axis or co-axis types, and which is expected to increase the number of multiplexing in angle multiplexed recording. In this multiplex recording system, two laser beams are used as reference beams, and the recorded data are reconstructed stably, even if there is shrinkage of the recording medium. In this paper, a reflection holographic memory system is explained in detail. In addition, the change in angle selectivity resulting from shrinkage of the medium is analyzed using the laminated film three-dimensional simulation method. As a result, we demonstrate that a dual-reference beam multiplex recording system is effective in reducing the influence of medium shrinkage.
Density Measurement System for Weights of 1 kg to 20 kg Using Hydrostatic Weighing
NASA Astrophysics Data System (ADS)
Lee, Yong Jae; Lee, Woo Gab; Abdurahman, Mohammed; Kim, Kwang Pyo
This paper presents a density measurement system to determine density of weights from 1 kg to 20 kg using hydrostatic weighing. The system works based on Archimedes principle. The density of reference liquid is determined using this setup while determining the density of the test weight. Density sphere is used as standard density ball to determine density of the reference liquid. A new immersion pan is designed for dual purpose to carry the density sphere and the cylindrical test weight for weighing in liquid. Main parts of the setup are an electronic balance, a thermostat controlled liquid bath, reference weights designed for bottom weighing, dual purpose immersion pans and stepping motors to load and unload in weighing process. The results of density measurement will be evaluated as uncertainties for weights of 1 kg to 20 kg.
Dual-Fuel Propulsion in Single-Stage Advanced Manned Launch System Vehicle
NASA Technical Reports Server (NTRS)
Lepsch, Roger A., Jr.; Stanley, Douglas O.; Unal, Resit
1995-01-01
As part of the United States Advanced Manned Launch System study to determine a follow-on, or complement, to the Space Shuttle, a reusable single-stage-to-orbit concept utilizing dual-fuel rocket propulsion has been examined. Several dual-fuel propulsion concepts were investigated. These include: a separate-engine concept combining Russian RD-170 kerosene-fueled engines with space shuttle main engine-derivative engines: the kerosene- and hydrogen-fueled Russian RD-701 engine; and a dual-fuel, dual-expander engine. Analysis to determine vehicle weight and size characteristics was performed using conceptual-level design techniques. A response-surface methodology for multidisciplinary design was utilized to optimize the dual-fuel vehicles with respect to several important propulsion-system and vehicle design parameters, in order to achieve minimum empty weight. The tools and methods employed in the analysis process are also summarized. In comparison with a reference hydrogen- fueled single-stage vehicle, results showed that the dual-fuel vehicles were from 10 to 30% lower in empty weight for the same payload capability, with the dual-expander engine types showing the greatest potential.
NASA Astrophysics Data System (ADS)
Chandra, C. V.; Moisseev, D. N.; Baldini, L.; Bechini, R.; Cremonini, R.; Wolff, D. B.; Petersen, W. A.; Junyent, F.; Chen, H.; Beauchamp, R.
2016-12-01
Dual-polarization weather radars have been widely used for rainfall measurement applications and studies of the microphysical characteristics of precipitation. Ground-based, dual-polarization radar systems form the cornerstones of national severe weather warning and forecasting infrastructure in many developed countries. As a result of the improved performance of dual-polarization radars for these applications, large scale dual-polarization upgrades are being planned for India and China. In addition to national forecast and warning operations, dual-polarization radars have also been used for satellite ground validation activities. The operational Dual-Polarization radars in the US are mostly S band systems whereas in Europe are mostly C band systems. In addition a third class of systems is emerging in urban regions where networks of X band systems are being deployed operationally. There are successful networks planned or already deployed in big cities such as Dallas Fort Worth, Tokyo or Beijing. These X band networks are developing their own operational domain. In summary a large infrastructure in terms of user specified products and dual use of operational research applications are also emerging in these systems. This paper will discuss some of the innovative uses of the operational dual-polarization radar networks for research purposes, with references to calibration, hydrometeor classification and quantitative precipitation estimation. Additional application to the study of precipitation processes will also be discussed.
Dual-view-zone tabletop 3D display system based on integral imaging.
He, Min-Yang; Zhang, Han-Le; Deng, Huan; Li, Xiao-Wei; Li, Da-Hai; Wang, Qiong-Hua
2018-02-01
In this paper, we propose a dual-view-zone tabletop 3D display system based on integral imaging by using a multiplexed holographic optical element (MHOE) that has the optical properties of two sets of microlens arrays. The MHOE is recorded by a reference beam using the single-exposure method. The reference beam records the wavefronts of a microlens array from two different directions. Thus, when the display beam is projected on the MHOE, two wavefronts with the different directions will be rebuilt and the 3D virtual images can be reconstructed in two viewing zones. The MHOE has angle and wavelength selectivity. Under the conditions of the matched wavelength and the angle of the display beam, the diffraction efficiency of the MHOE is greatest. Because the unmatched light just passes through the MHOE, the MHOE has the advantage of a see-through display. The experimental results confirm the feasibility of the dual-view-zone tabletop 3D display system.
Application of dual-fuel propulsion to a single stage AMLS vehicle
NASA Technical Reports Server (NTRS)
Lepsch, Roger A., Jr.; Stanley, Douglas O.; Unal, Resit
1993-01-01
As part of NASA's Advanced Manned Launch System (AMLS) study to determine a follow-on, or complement, to the Space Shuttle, a reusable single-stage-to-orbit concept utilizing dual-fuel rocket propulsion has been examined. Several dual-fuel propulsion concepts were investigated. These include: a separate engine concept combining Russian RD-170 kerosene-fueled engines with SSME-derivative engines; the kerosene and hydrogen-fueled Russian RD-701 engine concept; and a dual-fuel, dual-expander engine concept. Analysis to determine vehicle weight and size characteristics was performed using conceptual level design techniques. A response surface methodology for multidisciplinary design was utilized to optimize the dual-fuel vehicle concepts with respect to several important propulsion system and vehicle design parameters in order to achieve minimum empty weight. Comparisons were then made with a hydrogen-fueled reference, single-stage vehicle. The tools and methods employed in the analysis process are also summarized.
NASA Technical Reports Server (NTRS)
Hruby, R. J.; Bjorkman, W. S.
1977-01-01
Flight test results of the strapdown inertial reference unit (SIRU) navigation system are presented. The fault-tolerant SIRU navigation system features a redundant inertial sensor unit and dual computers. System software provides for detection and isolation of inertial sensor failures and continued operation in the event of failures. Flight test results include assessments of the system's navigational performance and fault tolerance.
Flight test results of the strapdown hexad inertial reference unit (SIRU). Volume 2: Test report
NASA Technical Reports Server (NTRS)
Hruby, R. J.; Bjorkman, W. S.
1977-01-01
Results of flight tests of the Strapdown Inertial Reference Unit (SIRU) navigation system are presented. The fault tolerant SIRU navigation system features a redundant inertial sensor unit and dual computers. System software provides for detection and isolation of inertial sensor failures and continued operation in the event of failures. Flight test results include assessments of the system's navigational performance and fault tolerance. Performance shortcomings are analyzed.
Interferometric at-wavelength flare characterization of EUV optical systems
Naulleau, Patrick P.; Goldberg, Kenneth Alan
2001-01-01
The extreme ultraviolet (EUV) phase-shifting point diffraction interferometer (PS/PDI) provides the high-accuracy wavefront characterization critical to the development of EUV lithography systems. Enhancing the implementation of the PS/PDI can significantly extend its spatial-frequency measurement bandwidth. The enhanced PS/PDI is capable of simultaneously characterizing both wavefront and flare. The enhanced technique employs a hybrid spatial/temporal-domain point diffraction interferometer (referred to as the dual-domain PS/PDI) that is capable of suppressing the scattered-reference-light noise that hinders the conventional PS/PDI. Using the dual-domain technique in combination with a flare-measurement-optimized mask and an iterative calculation process for removing flare contribution caused by higher order grating diffraction terms, the enhanced PS/PDI can be used to simultaneously measure both figure and flare in optical systems.
Black start research of the wind and storage system based on the dual master-slave control
NASA Astrophysics Data System (ADS)
Leng, Xue; Shen, Li; Hu, Tian; Liu, Li
2018-02-01
Black start is the key to solving the problem of large-scale power failure, while the introduction of new renewable clean energy as a black start power supply was a new hotspot. Based on the dual master-slave control strategy, the wind and storage system was taken as the black start reliable power, energy storage and wind combined to ensure the stability of the micorgrid systems, to realize the black start. In order to obtain the capacity ratio of the storage in the small system based on the dual master-slave control strategy, and the black start constraint condition of the wind and storage combined system, obtain the key points of black start of wind storage combined system, but also provide reference and guidance for the subsequent large-scale wind and storage combined system in black start projects.
Extended development of a sodium hydroxide thermal energy storage module
NASA Technical Reports Server (NTRS)
Rice, R. E.; Rowny, P. E.; Cohen, B. M.
1980-01-01
The post-test evaluation of a single heat exchanger sodium hydroxide thermal energy storage module for use in solar electric generation is reported. Chemical analyses of the storage medium used in the experimental model are presented. The experimental verification of the module performance using an alternate heat transfer fluid, Caloria HT-43, is described. Based on these results, a design analysis of a dual heat exchanger concept within the storage module is presented. A computer model and a reference design for the dual system (storage working fluid/power cycle working fluid) were completed. The dual system is estimated to have a capital cost of approximately one half that of the single heat exchanger concept.
Pardue, R.M.; Williams, R.R.
1980-09-12
A double-pass interferometer is provided which allows direct measurement of relative displacement between opposed surfaces. A conventional plane mirror interferometer may be modified by replacing the beam-measuring path cube-corner reflector with an additional quarterwave plate. The beam path is altered to extend to an opposed plane mirrored surface and the reflected beam is placed in interference with a retained reference beam split from dual-beam source and retroreflected by a reference cube-corner reflector mounted stationary with the interferometer housing. This permits direct measurement of opposed mirror surfaces by laser interferometry while doubling the resolution as with a conventional double-pass plane mirror laser interferometer system.
Pardue, Robert M.; Williams, Richard R.
1982-01-01
A double-pass interferometer is provided which allows direct measurement of relative displacement between opposed surfaces. A conventional plane mirror interferometer may be modified by replacing the beam-measuring path cube-corner reflector with an additional quarter-wave plate. The beam path is altered to extend to an opposed plane mirrored surface and the reflected beam is placed in interference with a retained reference beam split from dual-beam source and retroreflected by a reference cube-corner reflector mounted stationary with the interferometer housing. This permits direct measurement of opposed mirror surfaces by laser interferometry while doubling the resolution as with a conventional double-pass plane mirror laser interferometer system.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dall'Anese, Emiliano; Dhople, Sairaj V.; Giannakis, Georgios B.
2015-07-01
This paper considers a collection of networked nonlinear dynamical systems, and addresses the synthesis of feedback controllers that seek optimal operating points corresponding to the solution of pertinent network-wide optimization problems. Particular emphasis is placed on the solution of semidefinite programs (SDPs). The design of the feedback controller is grounded on a dual e-subgradient approach, with the dual iterates utilized to dynamically update the dynamical-system reference signals. Global convergence is guaranteed for diminishing stepsize rules, even when the reference inputs are updated at a faster rate than the dynamical-system settling time. The application of the proposed framework to the controlmore » of power-electronic inverters in AC distribution systems is discussed. The objective is to bridge the time-scale separation between real-time inverter control and network-wide optimization. Optimization objectives assume the form of SDP relaxations of prototypical AC optimal power flow problems.« less
General equilibrium characteristics of a dual-lift helicopter system
NASA Technical Reports Server (NTRS)
Cicolani, L. S.; Kanning, G.
1986-01-01
The equilibrium characteristics of a dual-lift helicopter system are examined. The system consists of the cargo attached by cables to the endpoints of a spreader bar which is suspended by cables below two helicopters. Results are given for the orientation angles of the suspension system and its internal forces, and for the helicopter thrust vector requirements under general circumstances, including nonidentical helicopters, any accelerating or static equilibrium reference flight condition, any system heading relative to the flight direction, and any distribution of the load to the two helicopters. Optimum tether angles which minimize the sum of the required thrust magnitudes are also determined. The analysis does not consider the attitude degrees of freedom of the load and helicopters in detail, but assumes that these bodies are stable, and that their aerodynamic forces in equilibrium flight can be determined independently as functions of the reference trajectory. The ranges of these forces for sample helicopters and loads are examined and their effects on the equilibrium characteristics are given parametrically in the results.
Wang, Jing-Min; Lu, Chia-Liang
2013-03-06
The dual threats of energy depletion and global warming place the development of methods for harnessing renewable energy resources at the center of public interest. Solar energy is one of the most promising renewable energy resources. Sun trackers can substantially improve the electricity production of a photovoltaic (PV) system. This paper proposes a novel design of a dual-axis solar tracking PV system which utilizes the feedback control theory along with a four-quadrant light dependent resistor (LDR) sensor and simple electronic circuits to provide robust system performance. The proposed system uses a unique dual-axis AC motor and a stand-alone PV inverter to accomplish solar tracking. The control implementation is a technical innovation that is a simple and effective design. In addition, a scaled-down laboratory prototype is constructed to verify the feasibility of the scheme. The effectiveness of the Sun tracker is confirmed experimentally. To conclude, the results of this study may serve as valuable references for future solar energy applications.
Wang, Jing-Min; Lu, Chia-Liang
2013-01-01
The dual threats of energy depletion and global warming place the development of methods for harnessing renewable energy resources at the center of public interest. Solar energy is one of the most promising renewable energy resources. Sun trackers can substantially improve the electricity production of a photovoltaic (PV) system. This paper proposes a novel design of a dual-axis solar tracking PV system which utilizes the feedback control theory along with a four-quadrant light dependent resistor (LDR) sensor and simple electronic circuits to provide robust system performance. The proposed system uses a unique dual-axis AC motor and a stand-alone PV inverter to accomplish solar tracking. The control implementation is a technical innovation that is a simple and effective design. In addition, a scaled-down laboratory prototype is constructed to verify the feasibility of the scheme. The effectiveness of the Sun tracker is confirmed experimentally. To conclude, the results of this study may serve as valuable references for future solar energy applications. PMID:23467030
Line-scan spectrum-encoded imaging by dual-comb interferometry.
Wang, Chao; Deng, Zejiang; Gu, Chenglin; Liu, Yang; Luo, Daping; Zhu, Zhiwei; Li, Wenxue; Zeng, Heping
2018-04-01
Herein, the method of spectrum-encoded dual-comb interferometry is introduced to measure a three-dimensional (3-D) profile with absolute distance information. By combining spectral encoding for wavelength-to-space mapping, dual-comb interferometry for decoding and optical reference for calibration, this system can obtain a 3-D profile of an object at a stand-off distance of 114 mm with a depth precision of 12 μm. With the help of the reference arm, the absolute distance, reflectivity distribution, and depth information are simultaneously measured at a 5 kHz line-scan rate with free-running carrier-envelope offset frequencies. To verify the concept, experiments are conducted with multiple objects, including a resolution test chart, a three-stair structure, and a designed "ECNU" letter chain. The results show a horizontal resolution of ∼22 μm and a measurement range of 1.93 mm.
Comments on dual-mode nuclear space power and propulsion system concepts
NASA Technical Reports Server (NTRS)
Layton, J. Preston; Grey, Jerry
1991-01-01
Some form of Dual-Mode Nuclear Space Power & Propulsion System (D-MNSP&PS) will be essential to spacefaring throughout teh solar system and that such systems must evolve as mankind moves into outer space. The initial D-MNPSP&PS Reference System should be based on (1) present (1990), and (2) advanced (1995) technology for use on comparable mission in the 2000 and 2005 time period respectively. D-MNSP&PS can be broken down into a number of subsystems: Nuclear subsystems including the energy source and controls for the release of thermal power at elevated temperatures; power conversion subsystems; waste heat rejection subsystems; and control and safety subsystems. These systems are briefly detailed.
1993-11-01
In this section, we recall definitions of dual linear incoherent KH,’ radar measurables, rainfall rate and the specific attenuation (7) due to...reflectivity data. Two different path lengths (d1,) 10 and 20 from a C-band dual linear polarization radar measurements, Km., have been considered...model for simulation of dual linear polarization radar 7. REFERENCES measurement fields", to be published on lEE 1. Leitao, M. J. and P. A. Watson
Liang, Chenju; He, Boyu
2018-05-01
The use of a dual oxidation system, which combines sodium persulfate (Na 2 S 2 O 8 , SPS) and hydrogen peroxide (H 2 O 2 , HP) is increasing as an in-situ chemical oxidation (ISCO) process for soil and groundwater remediation. An analytical method was assessed in this study for determining individual oxidant concentration in order to understand the interactions, and variations in the concentrations, of SPS and HP in aqueous systems containing both SPS and HP. The iodometric titration method was demonstrated to be capable of measuring total oxidant (SPS + HP) concentration; while the ceric sulfate titration method can be used specifically for measuring HP in the dual oxidation system without interfering with the iodometric titration. Therefore, SPS concentration can be deduced by subtraction of the HP concentration from the total oxidant concentration. Direct iodometric titration for determination of total oxidant at concentration above 20 mM exhibited <8% concentration. Based on the results of indirect determination of SPS in the dual oxidation system, an approximate 10% concentration variation was expected. This research may serve as a reference for measuring oxidant variations in this ISCO dual oxidant application. Copyright © 2018. Published by Elsevier Ltd.
System engineering approach to GPM retrieval algorithms
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rose, C. R.; Chandrasekar, V.
2004-01-01
System engineering principles and methods are very useful in large-scale complex systems for developing the engineering requirements from end-user needs. Integrating research into system engineering is a challenging task. The proposed Global Precipitation Mission (GPM) satellite will use a dual-wavelength precipitation radar to measure and map global precipitation with unprecedented accuracy, resolution and areal coverage. The satellite vehicle, precipitation radars, retrieval algorithms, and ground validation (GV) functions are all critical subsystems of the overall GPM system and each contributes to the success of the mission. Errors in the radar measurements and models can adversely affect the retrieved output values. Groundmore » validation (GV) systems are intended to provide timely feedback to the satellite and retrieval algorithms based on measured data. These GV sites will consist of radars and DSD measurement systems and also have intrinsic constraints. One of the retrieval algorithms being studied for use with GPM is the dual-wavelength DSD algorithm that does not use the surface reference technique (SRT). The underlying microphysics of precipitation structures and drop-size distributions (DSDs) dictate the types of models and retrieval algorithms that can be used to estimate precipitation. Many types of dual-wavelength algorithms have been studied. Meneghini (2002) analyzed the performance of single-pass dual-wavelength surface-reference-technique (SRT) based algorithms. Mardiana (2003) demonstrated that a dual-wavelength retrieval algorithm could be successfully used without the use of the SRT. It uses an iterative approach based on measured reflectivities at both wavelengths and complex microphysical models to estimate both No and Do at each range bin. More recently, Liao (2004) proposed a solution to the Do ambiguity problem in rain within the dual-wavelength algorithm and showed a possible melting layer model based on stratified spheres. With the No and Do calculated at each bin, the rain rate can then be calculated based on a suitable rain-rate model. This paper develops a system engineering interface to the retrieval algorithms while remaining cognizant of system engineering issues so that it can be used to bridge the divide between algorithm physics an d overall mission requirements. Additionally, in line with the systems approach, a methodology is developed such that the measurement requirements pass through the retrieval model and other subsystems and manifest themselves as measurement and other system constraints. A systems model has been developed for the retrieval algorithm that can be evaluated through system-analysis tools such as MATLAB/Simulink.« less
Gas Sensors Based on Single-Arm Waveguide Interferometers
NASA Technical Reports Server (NTRS)
Sarkisov, Sergey; Curley, Michael; Diggs, Darnell; Adamovsky, Grigory
1998-01-01
Various optical technologies can be implemented in chemical sensing. Sensitive, rugged, and compact systems will be more likely built using interferometric waveguide sensors. Currently existing sensors comprise dual-arm systems with external reference arm, dual-arm devices with internal reference arm such as integrated Mach-Zehnder interferometer, and single-arm systems which employ the interference between different waveguide modes. These latter ones are the most compact and rugged but still sensitive enough to monitor volatile pollutants such as NH3 coming out of industrial refrigerators and fertilizer plants and stocks, NO, NO2, SO2, emitted by industrial burning processes. Single-arm devices in planar waveguide configuration most frequently use two orthogonally polarized modes TE (sub i) and TM (sub i) of the same order i. Sensing effect is based on the difference in propagation conditions for the modes caused by the environment. However, dual-mode single-order interferometers still have relatively low sensitivity with respect to the environment related changes in the waveguide core because of small difference between propagation constants of TE (sub i) and TM (sub i) modes of the same order. Substantial sensitivity improvement without significant complication can be achieved for planar waveguide interferometers using modes of different orders with much greater difference between propagation constants.
A dual-channel fusion system of visual and infrared images based on color transfer
NASA Astrophysics Data System (ADS)
Pei, Chuang; Jiang, Xiao-yu; Zhang, Peng-wei; Liang, Hao-cong
2013-09-01
A dual-channel fusion system of visual and infrared images based on color transfer The increasing availability and deployment of imaging sensors operating in multiple spectrums has led to a large research effort in image fusion, resulting in a plethora of pixel-level image fusion algorithms. However, most of these algorithms have gray or false color fusion results which are not adapt to human vision. Transfer color from a day-time reference image to get natural color fusion result is an effective way to solve this problem, but the computation cost of color transfer is expensive and can't meet the request of real-time image processing. We developed a dual-channel infrared and visual images fusion system based on TMS320DM642 digital signal processing chip. The system is divided into image acquisition and registration unit, image fusion processing unit, system control unit and image fusion result out-put unit. The image registration of dual-channel images is realized by combining hardware and software methods in the system. False color image fusion algorithm in RGB color space is used to get R-G fused image, then the system chooses a reference image to transfer color to the fusion result. A color lookup table based on statistical properties of images is proposed to solve the complexity computation problem in color transfer. The mapping calculation between the standard lookup table and the improved color lookup table is simple and only once for a fixed scene. The real-time fusion and natural colorization of infrared and visual images are realized by this system. The experimental result shows that the color-transferred images have a natural color perception to human eyes, and can highlight the targets effectively with clear background details. Human observers with this system will be able to interpret the image better and faster, thereby improving situational awareness and reducing target detection time.
Attitude Heading Reference System Using MEMS Inertial Sensors with Dual-Axis Rotation
Kang, Li; Ye, Lingyun; Song, Kaichen; Zhou, Yang
2014-01-01
This paper proposes a low cost and small size attitude and heading reference system based on MEMS inertial sensors. A dual-axis rotation structure with a proper rotary scheme according to the design principles is applied in the system to compensate for the attitude and heading drift caused by the large gyroscope biases. An optimization algorithm is applied to compensate for the installation angle error between the body frame and the rotation table's frame. Simulations and experiments are carried out to evaluate the performance of the AHRS. The results show that the proper rotation could significantly reduce the attitude and heading drifts. Moreover, the new AHRS is not affected by magnetic interference. After the rotation, the attitude and heading are almost just oscillating in a range. The attitude error is about 3° and the heading error is less than 3° which are at least 5 times better than the non-rotation condition. PMID:25268911
Using Dual Process Models to Examine Impulsivity Throughout Neural Maturation.
Leshem, Rotem
2016-01-01
The multivariate construct of impulsivity is examined through neural systems and connections that comprise the executive functioning system. It is proposed that cognitive and behavioral components of impulsivity can be divided into two distinct groups, mediated by (1) the cognitive control system: deficits in top-down cognitive control processes referred to as action/cognitive impulsivity and (2) the socioemotional system: related to bottom-up affective/motivational processes referred to as affective impulsivity. Examination of impulsivity from a developmental viewpoint can guide future research, potentially enabling the selection of more effective interventions for impulsive individuals, based on the cognitive components requiring improvement.
Imboden, Mary T; Welch, Whitney A; Swartz, Ann M; Montoye, Alexander H K; Finch, Holmes W; Harber, Matthew P; Kaminsky, Leonard A
2017-01-01
Dual energy x-ray absorptiometry (DXA) is an established technique for the measurement of body composition. Reference values for these variables, particularly those related to fat mass, are necessary for interpretation and accurate classification of those at risk for obesity-related health complications and in need of lifestyle modifications (diet, physical activity, etc.). Currently, there are no reference values available for GE-Healthcare DXA systems and it is known that whole-body and regional fat mass measures differ by DXA manufacturer. To develop reference values by age and sex for DXA-derived fat mass measurements with GE-Healthcare systems. A de-identified sample of 3,327 participants (2,076 women, 1,251 men) was obtained from Ball State University's Clinical Exercise Physiology Laboratory and University of Wisconsin-Milwaukee's Physical Activity & Health Research Laboratory. All scans were completed using a GE Lunar Prodigy or iDXA and data reported included percent body fat (%BF), fat mass index (FMI), and ratios of android-to-gynoid (A/G), trunk/limb, and trunk/leg fat measurements. Percentiles were calculated and a factorial ANOVA was used to determine differences in the mean values for each variable between age and sex. Normative reference values for fat mass variables from DXA measurements obtained from GE-Healthcare DXA systems are presented as percentiles for both women and men in 10-year age groups. Women had higher (p<0.01) mean %BF and FMI than men, whereas men had higher (p<0.01) mean ratios of A/G, trunk/limb, and trunk/leg fat measurements than women. These reference values provide clinicians and researchers with a resource for interpretation of DXA-derived fat mass measurements specific to use with GE-Healthcare DXA systems.
ERIC Educational Resources Information Center
James, Carl
1993-01-01
Ostensive and expository definitions of applied linguistics are assessed. It is suggested that the key to a meaningful definition lies in the dual articulation of applied linguistics: it is an interface between linguistics and practicality. Its role as an "expert system" is suggested. (45 references) (Author/LB)
Implications of Dual Practice among Health Workers: A Systematic Review
MOGHRI, Javad; RASHIDIAN, Arash; ARAB, Mohammad; AKBARI SARI, Ali
2017-01-01
Background: Mixed health care systems to work simultaneously on both public and private facilities, is common today. This phenomenon referred to as dual practice (DP), has potential implications for access, quality, cost and equity of health services. This paper aimed to review systematically studies that assess the implications of DP among health workers. Methods: MEDLINE, EMBASE, and The Cochrane library were searched for obtaining published literature between Feb 1990 and May 2014. Google and Google Scholars, organizational websites, and reference lists of relevant papers searched to get grey literature. Only studies concentrated on consequences and impacts of DP among health professionals and conducted using “randomized controlled trials”, “non-randomized controlled trials”, “controlled before and after studies”, or “interrupted time series” were eligible for inclusion. Results: From 3242 records, we focused on 19 studies, which aimed to assess effects and impacts of dual practice. After that, the current understanding of DP positive and negative implications was categorized and discussed based on two perspectives. Conclusion: There has been a propensity to over-reliance on theoretical methods in predicting the implications of this phenomenon. Almost all of the mentioned implications are based on theoretical predictions undermined in the broader literature. Furthermore, assessing the current literature showed positive and negative impacts of DP on different parts of the health system and various dimensions of service delivery. These implications are contexted specific and may vary from system to system. PMID:28451549
Fringe formation in dual-hologram interferometry
NASA Technical Reports Server (NTRS)
Burner, A. W.
1990-01-01
Reference-fringe formation in nondiffuse dual-hologram interferometry is described by combining a first-order geometrical hologram treatment with interference fringes generated by two point sources. The first-order imaging relationships can be used to describe reference-fringe patterns for the geometry of the dual-hologram interferometry. The process can be completed without adjusting the two holograms when the reconstructing wavelength is less than the exposing wavelength, and the process is found to facilitate basic intereferometer adjustments.
Zhang, Tao; Gao, Feng; Jiang, Xiangqian
2017-10-02
This paper proposes an approach to measure double-sided near-right-angle structured surfaces based on dual-probe wavelength scanning interferometry (DPWSI). The principle and mathematical model is discussed and the measurement system is calibrated with a combination of standard step-height samples for both probes vertical calibrations and a specially designed calibration artefact for building up the space coordinate relationship of the dual-probe measurement system. The topography of the specially designed artefact is acquired by combining the measurement results with white light scanning interferometer (WLSI) and scanning electron microscope (SEM) for reference. The relative location of the two probes is then determined with 3D registration algorithm. Experimental validation of the approach is provided and the results show that the method is able to measure double-sided near-right-angle structured surfaces with nanometer vertical resolution and micrometer lateral resolution.
Wentzensen, Nicolas; Fetterman, Barbara; Tokugawa, Diane; Schiffman, Mark; Castle, Philip E; Wood, Shannon N; Stiemerling, Eric; Poitras, Nancy; Lorey, Thomas; Kinney, Walter
2014-12-01
Dual-stain cytology for p16 and Ki-67 has been proposed as a biomarker in cervical cancer screening. The authors evaluated the reproducibility and accuracy of dual-stain cytology among 10 newly trained evaluators. In total, 480 p16/Ki-67-stained slides from human papillomavirus-positive women were evaluated in masked fashion by 10 evaluators. None of the evaluators had previous experience with p16 or p16/Ki-67 cytology. All participants underwent p16/Ki-67 training and subsequent proficiency testing. Reproducibility of dual-stain cytology was measured using the percentage agreement, individual and aggregate κ values, as well as McNemar statistics. Clinical performance for the detection of cervical intraepithelial neoplasia grade 2 or greater (CIN2+) was evaluated for each individual evaluator and for all evaluators combined compared with the reference evaluation by a cytotechnologist who had extensive experience with dual-stain cytology. The percentage agreement of individual evaluators with the reference evaluation ranged from 83% to 91%, and the κ values ranged from 0.65 to 0.81. The combined κ value was 0.71 for all evaluators and 0.73 for cytotechnologists. The average sensitivity and specificity for the detection of CIN2+ among novice evaluators was 82% and 64%, respectively; whereas the reference evaluation had 84% sensitivity and 63% specificity, respectively. Agreement on dual-stain positivity increased with greater numbers of p16/Ki-67-positive cells on the slides. Good to excellent reproducibility of p16/Ki-67 dual-stain cytology was observed with almost identical clinical performance of novice evaluators compared with reference evaluations. The current findings suggest that p16/Ki-67 dual-stain evaluation can be implemented in routine cytology practice with limited training. © 2014 American Cancer Society.
NASA Astrophysics Data System (ADS)
Krzan, Grzegorz; Stępniak, Katarzyna
2017-09-01
In high-accuracy positioning using GNSS, the most common solution is still relative positioning using double-difference observations of dual-frequency measurements. An increasingly popular alternative to relative positioning are undifferenced approaches, which are designed to make full use of modern satellite systems and signals. Positions referenced to global International Terrestrial Reference Frame (ITRF2008) obtained from Precise Point Positioning (PPP) or Undifferenced (UD) network solutions have to be transformed to national (regional) reference frame, which introduces additional bases related to the transformation process. In this paper, satellite observations from two test networks using different observation time series were processed. The first test concerns the positioning accuracy from processing one year of dual-frequency GPS observations from 14 EUREF Permanent Network (EPN) stations using NAPEOS 3.3.1 software. The results were transformed into a national reference frame (PL-ETRF2000) and compared to positions from an EPN cumulative solution, which was adopted as the true coordinates. Daily observations were processed using PPP and UD multi-station solutions to determine the final accuracy resulting from satellite positioning, the transformation to national coordinate systems and Eurasian intraplate plate velocities. The second numerical test involved similar processing strategies of post-processing carried out using different observation time series (30 min., 1 hour, 2 hours, daily) and different classes of GNSS receivers. The centimeter accuracy of results presented in the national coordinate system satisfies the requirements of many surveying and engineering applications.
Image registration for a UV-Visible dual-band imaging system
NASA Astrophysics Data System (ADS)
Chen, Tao; Yuan, Shuang; Li, Jianping; Xing, Sheng; Zhang, Honglong; Dong, Yuming; Chen, Liangpei; Liu, Peng; Jiao, Guohua
2018-06-01
The detection of corona discharge is an effective way for early fault diagnosis of power equipment. UV-Visible dual-band imaging can detect and locate corona discharge spot at all-weather condition. In this study, we introduce an image registration protocol for this dual-band imaging system. The protocol consists of UV image denoising and affine transformation model establishment. We report the algorithm details of UV image preprocessing, affine transformation model establishment and relevant experiments for verification of their feasibility. The denoising algorithm was based on a correlation operation between raw UV images, a continuous mask and the transformation model was established by using corner feature and a statistical method. Finally, an image fusion test was carried out to verify the accuracy of affine transformation model. It has proved the average position displacement error between corona discharge and equipment fault at different distances in a 2.5m-20 m range are 1.34 mm and 1.92 mm in the horizontal and vertical directions, respectively, which are precise enough for most industrial applications. The resultant protocol is not only expected to improve the efficiency and accuracy of such imaging system for locating corona discharge spot, but also supposed to provide a more generalized reference for the calibration of various dual-band imaging systems in practice.
Coordinated Control of a Planar Dual-Crane Non-Fully Restrained System
2008-12-01
Support Over-The-Shore (HSOTS) 2007 in Puerto Quetzal , Guatemala. . . . . . . . . . . . . . 30 Figure 27. Reference frame and coordinate definitions...2007 in Puerto Quetzal , Guatemala. 30 require the construction an inverse of the Jacobian, but rather the transpose only. It is noted that the effector
Hydrophobic interaction chromatography in dual salt system increases protein binding capacity.
Senczuk, Anna M; Klinke, Ralph; Arakawa, Tsutomu; Vedantham, Ganesh; Yigzaw, Yinges
2009-08-01
Hydrophobic interaction chromatography (HIC) uses weakly hydrophobic resins and requires a salting-out salt to promote protein-resin interaction. The salting-out effects increase with protein and salt concentration. Dynamic binding capacity (DBC) is dependent on the binding constant, as well as on the flow characteristics during sample loading. DBC increases with the salt concentration but decreases with increasing flow rate. Dynamic and operational binding capacity have a major raw material cost/processing time impact on commercial scale production of monoclonal antibodies. In order to maximize DBC the highest salt concentration without causing precipitation is used. We report here a novel method to maintain protein solubility while increasing the DBC by using a combination of two salting-out salts (referred to as dual salt). In a series of experiments, we explored the dynamic capacity of a HIC resin (TosoBioscience Butyl 650M) with combinations of salts. Using a model antibody, we developed a system allowing us to increase the dynamic capacity up to twofold using the dual salt system over traditional, single salt system. We also investigated the application of this novel approach to several other proteins and salt combinations, and noted a similar protein solubility and DBC increase. The observed increase in DBC in the dual salt system was maintained at different linear flow rates and did not impact selectivity.
Luo, Ying; Chen, Yangquan; Pi, Youguo
2010-10-01
Cogging effect which can be treated as a type of position-dependent periodic disturbance, is a serious disadvantage of the permanent magnetic synchronous motor (PMSM). In this paper, based on a simulation system model of PMSM position servo control, the cogging force, viscous friction, and applied load in the real PMSM control system are considered and presented. A dual high-order periodic adaptive learning compensation (DHO-PALC) method is proposed to minimize the cogging effect on the PMSM position and velocity servo system. In this DHO-PALC scheme, more than one previous periods stored information of both the composite tracking error and the estimate of the cogging force is used for the control law updating. Asymptotical stability proof with the proposed DHO-PALC scheme is presented. Simulation is implemented on the PMSM servo system model to illustrate the proposed method. When the constant speed reference is applied, the DHO-PALC can achieve a faster learning convergence speed than the first-order periodic adaptive learning compensation (FO-PALC). Moreover, when the designed reference signal changes periodically, the proposed DHO-PALC can obtain not only faster convergence speed, but also much smaller final error bound than the FO-PALC. Copyright © 2010 ISA. Published by Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1982-01-01
Some of the conclusions reached as a result of this study are summarized. Waste form parameters for the reference cermet waste form are available only by analogy. Detail design of the waste payload would require determination of actual waste form properties. The billet configuration constraints for the cermet waste form limit the packing efficiency to slightly under 75% net volume. The effect of this packing inefficiency in reducing the net waste form per waste payload can be seen graphically. The cermet waste form mass per unit mass of waste payload is lower than that of the iodine waste form evenmore » though the cermet has a higher density (6.5 versus 5.5). This is because the lead iodide is cast achieving almost 100% efficiency in packing. This inefficiency in the packing of the cermet results in a 20% increase in number of flights which increases both cost and risk. Alternative systems for waste mixes requiring low flight rates (technetium-99, iodine-129) can make effective use of the existing 65K space transportation system in either single- or dual-launch scenarios. A comprehensive trade study would be required to select the optimum orbit transfer system for low-launch-rate systems. This study was not conducted as part of the present effort due to selection of the cermet waste form as the reference for the study. Several candidates look attractive for both single- and dual-launch systems (see sec. 4.4), but due to the relatively small number of missions, a comprehensive comparison of life cycle costs including DDT and E would be required to select the best system. The reference system described in sections 5.0, 6.0, 7.0, and 8.0 offers the best combination of cost, risk, and alignment with ongoing NASA technology development efforts for disposal of the reference cermet waste form.« less
Laser-based ultrasonics by dual-probe interferometer detection and narrow-band ultrasound generation
NASA Astrophysics Data System (ADS)
Huang, Jin
1993-01-01
Despite the advantages of laser-based ultrasonic (LBU) systems, the overall sensitivity of LBU systems needs to be improved for practical applications. Progress is reported to achieve better LBU detection accuracy and sensitivity for applications with surface waves and Lamb waves. A novel dual-probe laser interferometer has been developed to measure the same signal at two points. The dual-probe interferometer is a modification of a conventional single-probe interferometer in that the reference beam is guided to a second detecting point on the specimen surface to form a differential measurement mode, which measure the difference of the displacements at the two points. This dual-probe interferometer is particularly useful for accurate measurements of the speed and attenuation of surface waves and Lamb waves. The dual-probe interferometer has been applied to obtain accurate measurements of the surface wave speed and attenuation on surfaces of increasing surface roughness. It has also been demonstrated that with an appropriate signal processing method, namely, the power cepstrum method, the dual-probe interferometer is applicable to measure the local surface wave speed even when the probe separation is so small that the two waveforms in the interferometer output signal overlap in the time domain. Narrow-band signal generation and detection improve the sensitivity of LBU systems. It is proposed to use a diffraction grating to form an array of illuminating strips which form a source of narrowband surface and Lamb waves. The line-array of thermoelastic sources generates narrow-band signals whose frequency and bandwidth can be easily controlled. The optimum line-array parameters, such as width, spacing and the number of lines in the array have been derived theoretically and verified experimentally. Narrow-band signal generation with optimum parameters has been demonstrated. The enhanced LBU system with dual-probe detection and narrowband signal generation has been successfully applied to the detection of cracks emanating from rivet holes in aircraft fuselage panel samples. A compact fiber-optic dual-probe interferometer has also been developed and applied to the above mentioned problem of crack detection. Results agree well with those obtained with a bulk LBU system.
Holographic interferometry with an injection seeded Nd:YAG laser and two reference beams
NASA Technical Reports Server (NTRS)
Decker, Arthur J.
1989-01-01
The performance of twin injection seeded Nd:YAG lasers is compared with the performance of an argon-ion laser for recording dual-reference-beam holograms in AGFA 8E56 emulsion. Optical heterodyning is used to measure interference, and the results are expressed in terms of heterodyning signal level and intensity signal-to-noise. The Nd:YAG laser system is to be used for optical inspections of structures for cracks, defects, gas leaks, and structural changes.
GR712RC- Dual-Core Processor- Product Status
NASA Astrophysics Data System (ADS)
Sturesson, Fredrik; Habinc, Sandi; Gaisler, Jiri
2012-08-01
The GR712RC System-on-Chip (SoC) is a dual core LEON3FT system suitable for advanced high reliability space avionics. Fault tolerance features from Aeroflex Gaisler’s GRLIB IP library and an implementation using Ramon Chips RadSafe cell library enables superior radiation hardness.The GR712RC device has been designed to provide high processing power by including two LEON3FT 32- bit SPARC V8 processors, each with its own high- performance IEEE754 compliant floating-point-unit and SPARC reference memory management unit.This high processing power is combined with a large number of serial interfaces, ranging from high-speed links for data transfers to low-speed control buses for commanding and status acquisition.
Fan, Bo; Shepherd, John A; Levine, Michael A; Steinberg, Dee; Wacker, Wynn; Barden, Howard S; Ergun, David; Wu, Xin P
2014-01-01
The National Health and Nutrition Examination Survey (NHANES 1999-2004) includes adult and pediatric comparisons for total body bone and body composition results. Because dual-energy x-ray absorptiometry (DXA) measurements from different manufacturers are not standardized, NHANES reference values currently are applicable only to a single make and model of Hologic DXA system. The purpose of this study was to derive body composition reference curves for GE Healthcare Lunar DXA systems. Published values from the NHANES 1999-2004 survey were acquired from the Centers for Disease Control and Prevention website. Using previously reported cross-calibration equations between Hologic and GE-Lunar, we converted the total body and regional bone and soft-tissue measurements from NHANES 1999-2004 to GE-Lunar values. The LMS (LmsChartMaker Pro Version 3.5) curve fitting method was used to generate GE-Lunar reference curves. Separate curves were generated for each sex and ethnicity. The reference curves were also divided into pediatric (≤20 years old) and adult (>20 years old) groups. Adult reference curves were derived as a function of age. Additional relationships of pediatric DXA values were derived as a function of height, lean mass, and bone area. Robustness was tested between Hologic and GE-Lunar Z-score values. The NHANES 1999-2004 survey included a sample of 20,672 participants' (9630 female) DXA scans. A total of 8056 participants were younger than 20 yr and were included in the pediatric reference data set. Participants enrolled in the study who weighed more than 136 kg (over scanner table limit) were excluded. The average Z-scores comparing the new GE-Lunar reference curves are close to zero, and the standard deviation of the Z-scores are close to one for all variables. As expected, all measurements on the GE-Lunar reference curves for participants younger than 20 yr increase monotonically with age. In the adult population, most of the curves are constant at younger age and drop moderately as age increases. We have presented NHANES reference curves applicable to DXA whole-body scans acquired on GE Healthcare Lunar systems by age, sex and ethnicity. Users of GE Healthcare GE-Lunar DXA systems can now benefit from the large body composition reference data set collected in the NHANES 1999-2004 study. Copyright © 2014 The International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.
Basic Needs and the Development of Interest and Intrinsic Motivational Orientations
ERIC Educational Resources Information Center
Krapp, Andreas
2005-01-01
From the perspective of the ''person-object-theory of interest'' (POI) the development of interest and interest-related motivational orientations can be explained at the level of functional principles by referring to a dual regulation system that consists of both, cognitive-rational and partly subconscious emotional control mechanisms. Within this…
Canadian Schools in Transition: Moving from Dual Education Systems to Inclusive Schools.
ERIC Educational Resources Information Center
Lupart, Judy; Webber, Charles
2002-01-01
This article analyzes the many meanings of school restructuring and highlights the ongoing nature of school reform in Canadian schools. Following a selective chronology of general and special education reform, it attempts to capture what appear to be the key features of school reform and progressive inclusion. (Contains references.) (Author/CR)
Dual Enrollment Programs. What Works Clearinghouse Intervention Report
ERIC Educational Resources Information Center
What Works Clearinghouse, 2017
2017-01-01
"Dual enrollment" programs allow high school students to take college courses and earn college credits while still attending high school. Such programs, also referred to as "dual credit" or early college programs, are designed to boost college access and degree attainment, especially for students typically underrepresented in…
NASA Astrophysics Data System (ADS)
Gozzard, David R.; Schediwy, Sascha W.; Dodson, Richard; Rioja, María J.; Hill, Mike; Lennon, Brett; McFee, Jock; Mirtschin, Peter; Stevens, Jamie; Grainge, Keith
2017-07-01
In order to meet its cutting-edge scientific objectives, the Square Kilometre Array (SKA) telescope requires high-precision frequency references to be distributed to each of its antennas. The frequency references are distributed via fiber-optic links and must be actively stabilized to compensate for phase noise imposed on the signals by environmental perturbations on the links. SKA engineering requirements demand that any proposed frequency reference distribution system be proved in “astronomical verification” tests. We present results of the astronomical verification of a stabilized frequency reference transfer system proposed for SKA-mid. The dual-receiver architecture of the Australia Telescope Compact Array was exploited to subtract the phase noise of the sky signal from the data, allowing the phase noise of observations performed using a standard frequency reference, as well as the stabilized frequency reference transfer system transmitting over 77 km of fiber-optic cable, to be directly compared. Results are presented for the fractional frequency stability and phase drift of the stabilized frequency reference transfer system for celestial calibrator observations at 5 and 25 GHz. These observations plus additional laboratory results for the transferred signal stability over a 166 km metropolitan fiber-optic link are used to show that the stabilized transfer system under test exceeds all SKA phase-stability requirements within a broad range of observing conditions. Furthermore, we have shown that alternative reference dissemination systems that use multiple synthesizers to supply reference signals to sub-sections of an array may limit the imaging capability of the telescope.
Increased integrity of white matter pathways after dual n-back training.
Salminen, Tiina; Mårtensson, Johan; Schubert, Torsten; Kühn, Simone
2016-06-01
Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training study showed increased white matter integrity in the parietal lobe as well as the anterior part of the corpus callosum after visual n-back training. We investigated dual n-back training-related changes in white matter pathways. We anticipated dual n-back training to increase white matter integrity in pathways that connect brain regions related to WM processes. Additionally, we hypothesized that dual n-back training would produce more brain-wide white matter changes than single n-back training because of the involvement of two modalities and the additional dual-task coordination component of the task. The dual n-back training group showed increased white matter integrity (reflected as increased fractional anisotropy, FA) after training. The effects were mostly left lateralized as compared with changes from pretest to posttest in the passive and active control groups. Additionally, significant effects were observed in the anterior part of the corpus callosum, when the training group was compared with the passive control group. There were no changes in pretest to posttest FA changes between the passive and active control groups. The results therefore show that dual n-back training produces increased integrity in white matter pathways connecting different brain regions. The results are discussed in reference to the bi-modal dual-task component of the training task. Copyright © 2016 Elsevier Inc. All rights reserved.
Recalibrating Reference within a Dual-Space Interaction Environment
ERIC Educational Resources Information Center
Zemel, Alan; Koschmann, Timothy
2013-01-01
In this paper we examine how two groups of middle school students arrive at shared understandings of and solutions to mathematical problems. Our data consists of logs of student participation in the Virtual Math Teams (VMT) system as they work on math problems. The project supports interaction both through chat and through a virtual whiteboard. We…
Publications - GMC 429 | Alaska Division of Geological & Geophysical
DGGS GMC 429 Publication Details Title: Quantitative Fluorescence Technology - Dual Wavelength (QFT2 Bibliographic Reference Canrig Drilling Technology Ltd., 2014, Quantitative Fluorescence Technology - Dual
Effect of inertia properties on attitude stability of nonrigid spin-stabilized spacecraft
NASA Technical Reports Server (NTRS)
Lang, W. E.; Young, J. P.
1974-01-01
The phenomenon of energy dissipation in spinning spacecraft is discussed with particular reference to its dependence on spacecraft inertia properties. Specific dissipation mechanisms are identified. The effect of external environmental factors on spin stability is also discussed. Generalized curves are presented relating system stability to the principal inertia ratio for various forms of energy dissipation. Dual-spin systems and the effect of lateral inertia asymmetry are also reviewed.
Fringe Formation in Dual-Hologram Interferometry
NASA Technical Reports Server (NTRS)
Burner, A. W.
1989-01-01
A first order geometrical optics treatment of holograms combined with the generation of interference fringes by two point sources is used to describe reference fringe formation in non-diffuse dual-hologram interferometry.
Comparison of Kinetic Models for Dual-Tracer Receptor Concentration Imaging in Tumors
Hamzei, Nazanin; Samkoe, Kimberley S; Elliott, Jonathan T; Holt, Robert W; Gunn, Jason R; Hasan, Tayyaba; Pogue, Brian W; Tichauer, Kenneth M
2014-01-01
Molecular differences between cancerous and healthy tissue have become key targets for novel therapeutics specific to tumor receptors. However, cancer cell receptor expression can vary within and amongst different tumors, making strategies that can quantify receptor concentration in vivo critical for the progression of targeted therapies. Recently a dual-tracer imaging approach capable of providing quantitative measures of receptor concentration in vivo was developed. It relies on the simultaneous injection and imaging of receptor-targeted tracer and an untargeted tracer (to account for non-specific uptake of the targeted tracer). Early implementations of this approach have been structured on existing “reference tissue” imaging methods that have not been optimized for or validated in dual-tracer imaging. Using simulations and mouse tumor model experimental data, the salient findings in this study were that all widely used reference tissue kinetic models can be used for dual-tracer imaging, with the linearized simplified reference tissue model offering a good balance of accuracy and computational efficiency. Moreover, an alternate version of the full two-compartment reference tissue model can be employed accurately by assuming that the K1s of the targeted and untargeted tracers are similar to avoid assuming an instantaneous equilibrium between bound and free states (made by all other models). PMID:25414912
System-level Analysis of Food Moisture Content Requirements for the Mars Dual Lander Transit Mission
NASA Technical Reports Server (NTRS)
Levri, Julie A.; Perchonok, Michele H.
2004-01-01
In order to ensure that adequate water resources are available during a mission, any net water loss from the habitat must be balanced with an equivalent amount of required makeup water. Makeup water may come from a variety of sources, including water in shipped tanks, water stored in prepackaged food, product water from fuel cells, and in-situ water resources. This paper specifically addresses the issue of storing required makeup water in prepackaged food versus storing the water in shipped tanks for the Mars Dual Lander Transit Mission, one of the Advanced Life Support Reference Missions. In this paper, water mass balances have been performed for the Dual Lander Transit Mission, to determine the necessary requirement of makeup water under nominal operation (i.e. no consideration of contingency needs), on a daily basis. Contingency issues are briefly discussed with respect to impacts on makeup water storage (shipped tanks versus storage in prepackaged food). The Dual Lander Transit Mission was selected for study because it has been considered by the Johnson Space Center Exploration Office in enough detail to define a reasonable set of scenario options for nominal system operation and contingencies. This study also illustrates the concept that there are multiple, reasonable life support system scenarios for any one particular mission. Thus, the need for a particular commodity can depend upon many variables in the system. In this study, we examine the need for makeup water as it depends upon the configuration of the rest of the life support system.
Scolaro, Loretta; Lorenser, Dirk; Madore, Wendy-Julie; Kirk, Rodney W.; Kramer, Anne S.; Yeoh, George C.; Godbout, Nicolas; Sampson, David D.; Boudoux, Caroline; McLaughlin, Robert A.
2015-01-01
Molecular imaging using optical techniques provides insight into disease at the cellular level. In this paper, we report on a novel dual-modality probe capable of performing molecular imaging by combining simultaneous three-dimensional optical coherence tomography (OCT) and two-dimensional fluorescence imaging in a hypodermic needle. The probe, referred to as a molecular imaging (MI) needle, may be inserted tens of millimeters into tissue. The MI needle utilizes double-clad fiber to carry both imaging modalities, and is interfaced to a 1310-nm OCT system and a fluorescence imaging subsystem using an asymmetrical double-clad fiber coupler customized to achieve high fluorescence collection efficiency. We present, to the best of our knowledge, the first dual-modality OCT and fluorescence needle probe with sufficient sensitivity to image fluorescently labeled antibodies. Such probes enable high-resolution molecular imaging deep within tissue. PMID:26137379
Postmortem validation of breast density using dual-energy mammography
Molloi, Sabee; Ducote, Justin L.; Ding, Huanjun; Feig, Stephen A.
2014-01-01
Purpose: Mammographic density has been shown to be an indicator of breast cancer risk and also reduces the sensitivity of screening mammography. Currently, there is no accepted standard for measuring breast density. Dual energy mammography has been proposed as a technique for accurate measurement of breast density. The purpose of this study is to validate its accuracy in postmortem breasts and compare it with other existing techniques. Methods: Forty postmortem breasts were imaged using a dual energy mammography system. Glandular and adipose equivalent phantoms of uniform thickness were used to calibrate a dual energy basis decomposition algorithm. Dual energy decomposition was applied after scatter correction to calculate breast density. Breast density was also estimated using radiologist reader assessment, standard histogram thresholding and a fuzzy C-mean algorithm. Chemical analysis was used as the reference standard to assess the accuracy of different techniques to measure breast composition. Results: Breast density measurements using radiologist reader assessment, standard histogram thresholding, fuzzy C-mean algorithm, and dual energy were in good agreement with the measured fibroglandular volume fraction using chemical analysis. The standard error estimates using radiologist reader assessment, standard histogram thresholding, fuzzy C-mean, and dual energy were 9.9%, 8.6%, 7.2%, and 4.7%, respectively. Conclusions: The results indicate that dual energy mammography can be used to accurately measure breast density. The variability in breast density estimation using dual energy mammography was lower than reader assessment rankings, standard histogram thresholding, and fuzzy C-mean algorithm. Improved quantification of breast density is expected to further enhance its utility as a risk factor for breast cancer. PMID:25086548
Postmortem validation of breast density using dual-energy mammography
DOE Office of Scientific and Technical Information (OSTI.GOV)
Molloi, Sabee, E-mail: symolloi@uci.edu; Ducote, Justin L.; Ding, Huanjun
2014-08-15
Purpose: Mammographic density has been shown to be an indicator of breast cancer risk and also reduces the sensitivity of screening mammography. Currently, there is no accepted standard for measuring breast density. Dual energy mammography has been proposed as a technique for accurate measurement of breast density. The purpose of this study is to validate its accuracy in postmortem breasts and compare it with other existing techniques. Methods: Forty postmortem breasts were imaged using a dual energy mammography system. Glandular and adipose equivalent phantoms of uniform thickness were used to calibrate a dual energy basis decomposition algorithm. Dual energy decompositionmore » was applied after scatter correction to calculate breast density. Breast density was also estimated using radiologist reader assessment, standard histogram thresholding and a fuzzy C-mean algorithm. Chemical analysis was used as the reference standard to assess the accuracy of different techniques to measure breast composition. Results: Breast density measurements using radiologist reader assessment, standard histogram thresholding, fuzzy C-mean algorithm, and dual energy were in good agreement with the measured fibroglandular volume fraction using chemical analysis. The standard error estimates using radiologist reader assessment, standard histogram thresholding, fuzzy C-mean, and dual energy were 9.9%, 8.6%, 7.2%, and 4.7%, respectively. Conclusions: The results indicate that dual energy mammography can be used to accurately measure breast density. The variability in breast density estimation using dual energy mammography was lower than reader assessment rankings, standard histogram thresholding, and fuzzy C-mean algorithm. Improved quantification of breast density is expected to further enhance its utility as a risk factor for breast cancer.« less
NASA Astrophysics Data System (ADS)
Delay, Frederick; Badri, Hamid; Fahs, Marwan; Ackerer, Philippe
2017-12-01
Dual porosity models become increasingly used for simulating groundwater flow at the large scale in fractured porous media. In this context, model inversions with the aim of retrieving the system heterogeneity are frequently faced with huge parameterizations for which descent methods of inversion with the assistance of adjoint state calculations are well suited. We compare the performance of discrete and continuous forms of adjoint states associated with the flow equations in a dual porosity system. The discrete form inherits from previous works by some of the authors, as the continuous form is completely new and here fully differentiated for handling all types of model parameters. Adjoint states assist descent methods by calculating the gradient components of the objective function, these being a key to good convergence of inverse solutions. Our comparison on the basis of synthetic exercises show that both discrete and continuous adjoint states can provide very similar solutions close to reference. For highly heterogeneous systems, the calculation grid of the continuous form cannot be too coarse, otherwise the method may show lack of convergence. This notwithstanding, the continuous adjoint state is the most versatile form as its non-intrusive character allows for plugging an inversion toolbox quasi-independent from the code employed for solving the forward problem.
Seat, H C; Chawah, P; Cattoen, M; Sourice, A; Plantier, G; Boudin, F; Chéry, J; Brunet, C; Bernard, P; Suleiman, M
2012-07-15
This Letter describes a dual-amplitude modulation technique incorporated into a double reflection extrinsic-type fiber Fabry-Perot interferometer to measure periodic, nonperiodic as well as quasi-static displacements. The modulation scheme simultaneously maintains the interference signal pair in quadrature and provides a reference signal for displacements inferior to a quarter of the source wavelength. The control and phase demodulation of the interferometer carried out via software enable quasi-real-time measurement and facilitates sensor alignment. The sensor system can be exploited in the low frequency range from 10(-3) to ∼500 Hz and has a resolution better than 2.2 nm, targeting applications in geophysics.
System-independent characterization of materials using dual-energy computed tomography
Azevedo, Stephen G.; Martz, Jr., Harry E.; Aufderheide, III, Maurice B.; ...
2016-02-01
In this study, we present a new decomposition approach for dual-energy computed tomography (DECT) called SIRZ that provides precise and accurate material description, independent of the scanner, over diagnostic energy ranges (30 to 200 keV). System independence is achieved by explicitly including a scanner-specific spectral description in the decomposition method, and a new X-ray-relevant feature space. The feature space consists of electron density, ρ e, and a new effective atomic number, Z e, which is based on published X-ray cross sections. Reference materials are used in conjunction with the system spectral response so that additional beam-hardening correction is not necessary.more » The technique is tested against other methods on DECT data of known specimens scanned by diverse spectra and systems. Uncertainties in accuracy and precision are less than 3% and 2% respectively for the (ρ e, Z e) results compared to prior methods that are inaccurate and imprecise (over 9%).« less
Wind-Tunnel Tests of Single- and Dual-Rotating Pusher Propellers Having from Three to Eight Blades
1942-02-01
propellor, dual rotation ch.arnctorlstic curves for elx-blade propollor, sin~lo rotnt%on -charnctoristlc curves for six-l) lado propollor, (dual...results of the “pusher tests are in general agreo- “ment“with” the traetior “tests previously Feportsd (refer- ences 1 End 2) a,e regarde the effect of
Fu, Wei; Wei, Shuang; Wang, Chenguang; Du, Zhixin; Zhu, Pengyu; Wu, Xiyang; Wu, Gang; Zhu, Shuifang
2017-08-15
High throughput screening systems are the preferred solution to meet the urgent requirement of increasing number of genetically modified organisms (GMOs). In this study, we have successfully developed a multiplex GMO element screening system with dual priming oligonucleotide (DPO) primers. This system can detect the cauliflower mosaic virus 35S (CaMV 35S), terminator of nopaline synthase gene (NOS), figwort mosaic virus 35S (FMV 35S) promoter, neomycin phosphotransferaseII (NPTII), Bt Cry 1Ab, phosphinothricin acetyltransferase genes (bar) and Streptomyces viridochromogenes (pat) simultaneously, which covers more than 90% of all authorized GMO species worldwide. This system exhibits a high tolerance to annealing temperatures, high specificity and a limit of detection equal to conventional PCR. A total of 214 samples from markets, national entry-exit agencies, the Institute for Reference Materials and Measurement (IRMM) and the American Oil Chemists' Society (AOCS) were also tested for applicability. This screening system is therefore suitable for GMO screening. Copyright © 2017 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
MacQueen, David A.; Dalrymple, Savannah R.; Drobes, David J.; Diamond, David M.
2016-01-01
Developed as a tool to assess working memory capacity in rodents, the odor span task (OST) has significant potential to advance drug discovery in animal models of psychiatric disorders. Prior investigations indicate OST performance is impaired by systemic administration of N-methyl-D-aspartate receptor (NMDA-r) antagonists and is sensitive to…
Tactical Unmanned Ground Vehicle Related Research References (BTA Study)
1993-03-01
draw bar pull - 4,297 lbs; Engine - 65 hp air cooled diesel engine ; dual electrical motors, hydrostatic drive; Observation - three closed-circuit...8217 Munitions and Chemical Command. Commander, U. S. Army Chemical Research, Development, and Engineering Center. 40..... "Unmanned Air Vehicles Payloads...8217 Larry Brantley Advanced Systems Concepts Office Research, Development, and Engineering Center MARCH 1993 edetone qArs nal, Alabama 35898-5000
Patient Satisfaction in Military Dental Treatment Facilities
2006-03-07
assessing satisfaction. Dental Patient Satisfaction 58 References Abidi, H. (2003). Encyclopedia of Social Sciences Research Methods . Thousand Oaks (CA...Care System that gave me the opportunity to attend the Baylor Program and to complete the dual Masters in Business Administration program at The...Patient satisfaction is an integral component of the report cards and thus military dentistry had to develop a method of standardizing the assessment of
NASA Astrophysics Data System (ADS)
Fard, Ali M.; Gardecki, Joseph A.; Ughi, Giovanni J.; Hyun, Chulho; Tearney, Guillermo J.
2016-02-01
Intravascular optical coherence tomography (OCT) is a high-resolution catheter-based imaging method that provides three-dimensional microscopic images of coronary artery in vivo, facilitating coronary artery disease treatment decisions based on detailed morphology. Near-infrared spectroscopy (NIRS) has proven to be a powerful tool for identification of lipid-rich plaques inside the coronary walls. We have recently demonstrated a dual-modality intravascular imaging technology that integrates OCT and NIRS into one imaging catheter using a two-fiber arrangement and a custom-made dual-channel fiber rotary junction. It therefore enables simultaneous acquisition of microstructural and composition information at 100 frames/second for improved diagnosis of coronary lesions. The dual-modality OCT-NIRS system employs a single wavelength-swept light source for both OCT and NIRS modalities. It subsequently uses a high-speed photoreceiver to detect the NIRS spectrum in the time domain. Although use of one light source greatly simplifies the system configuration, such light source exhibits pulse-to-pulse wavelength and intensity variation due to mechanical scanning of the wavelength. This can be in particular problematic for NIRS modality and sacrifices the reliability of the acquired spectra. In order to address this challenge, here we developed a robust data acquisition and processing method that compensates for the spectral variations of the wavelength-swept light source. The proposed method extracts the properties of the light source, i.e., variation period and amplitude from a reference spectrum and subsequently calibrates the NIRS datasets. We have applied this method on datasets obtained from cadaver human coronary arteries using a polygon-scanning (1230-1350nm) OCT system, operating at 100,000 sweeps per second. The results suggest that our algorithm accurately and robustly compensates the spectral variations and visualizes the dual-modality OCT-NIRS images. These findings are therefore crucial for the practical application and clinical translation of dual-modality intravascular OCT-NIRS imaging when the same swept sources are used for both OCT and spectroscopy.
Networked differential GPS system
NASA Technical Reports Server (NTRS)
Sheynblat, Leonid (Inventor); Kalafus, Rudolph M. (Inventor); Loomis, Peter V. W. (Inventor); Mueller, K. Tysen (Inventor)
1994-01-01
An embodiment of the present invention relates to a worldwide network of differential GPS reference stations (NDGPS) that continually track the entire GPS satellite constellation and provide interpolations of reference station corrections tailored for particular user locations between the reference stations Each reference station takes real-time ionospheric measurements with codeless cross-correlating dual-frequency carrier GPS receivers and computes real-time orbit ephemerides independently. An absolute pseudorange correction (PRC) is defined for each satellite as a function of a particular user's location. A map of the function is constructed, with iso-PRC contours. The network measures the PRCs at a few points, so-called reference stations and constructs an iso-PRC map for each satellite. Corrections are interpolated for each user's site on a subscription basis. The data bandwidths are kept to a minimum by transmitting information that cannot be obtained directly by the user and by updating information by classes and according to how quickly each class of data goes stale given the realities of the GPS system. Sub-decimeter-level kinematic accuracy over a given area is accomplished by establishing a mini-fiducial network.
Colombo, Giorgio L; Andreis, Ivo A Bergamo; Di Matteo, Sergio; Bruno, Giacomo M; Mondellini, Claudio
2013-01-01
The utilization of diagnostic imaging has substantially increased over the past decade in Europe and North America and continues to grow worldwide. The purpose of this study was to develop an economic evaluation of a syringeless power injector (PI) versus a dual-syringe PI for contrast enhanced computed tomography (CECT) in a hospital setting. Patients (n=2379) were enrolled at the Legnano Hospital between November 2012 and January 2013. They had been referred to the hospital for a CECT analysis and were randomized into two groups. The first group was examined with a 256-MDCT (MultiDetector Computed Tomography) scanner using a syringeless power injector, while the other group was examined with a 64-MDCT scanner using a dual-syringe. Data on the operators' time required in the patient analysis steps as well as on the quantity of consumable materials used were collected. The radiologic technologists' satisfaction with the use of the PIs was rated on a 10-point scale. A budget impact analysis and sensitivity analysis were performed under the base-case scenario. A total of 1,040 patients were examined using the syringeless system, and 1,339 with the dual-syringe system; the CECT examination quality was comparable for both PI systems. Equipment preparation time and releasing time per examination for syringeless PIs versus dual-syringe PIs were 100±30 versus 180±30 seconds and 90±30 and 140±20 seconds, respectively. On average, 10±3 mL of contrast media (CM) wastage per examination was observed with the dual-syringe PI and 0±1 mL with the syringeless PI. Technologists had higher satisfaction with the syringeless PI than with the dual-syringe system (8.8 versus 8.0). The syringeless PI allows a saving of about €6.18 per patient, both due to the lower cost of the devices and to the better performance of the syringeless system. The univariate sensitivity analysis carried out on the base-case results within the standard deviation range confirmed the saving generated by using the syringeless device, with saving values between €5.40 and €6.20 per patient. The syringeless PI was found to be more user-friendly and efficient, minimizing contrast wastage and providing similar contrast enhancement quality compared to the dual-syringe injector, with comparable CECT examination quality.
ERIC Educational Resources Information Center
Klimitchek, Michelle Leigh
2017-01-01
Texas House Bill 505 expanded dual credit programs to include high school freshmen and sophomores. This study examined the relationship of high school student characteristics and academic success in first attempt dual credit courses. Characteristics refer to year in high school, gender, and high school size. Success is passing scores in English,…
ERIC Educational Resources Information Center
Salerno, Mitchell Acri
2011-01-01
A phenomenological study utilizing the Consensual Qualitative Research method was conducted to understand the motivation of high school students dually enrolled in high school and college, commonly referred to as dual enrollment, in relation to the Self-Determination Theory and to connect this motivation to research on personal calling. This…
van der Gijp, Anouk; Webb, Emily M; Naeger, David M
2017-06-01
Scholars have identified two distinct ways of thinking. This "Dual Process Theory" distinguishes a fast, nonanalytical way of thinking, called "System 1," and a slow, analytical way of thinking, referred to as "System 2." In radiology, we use both methods when interpreting and reporting images, and both should ideally be emphasized when educating our trainees. This review provides practical tips for improving radiology education, by enhancing System 1 and System 2 thinking among our trainees. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.
Dual Mode Green Propulsion for Revolutionary Performance Gains with Minimal Recurring Investments
NASA Astrophysics Data System (ADS)
Dankanich, J. W.; Lozano, P. C.
2017-02-01
Dual mode green propulsion has potential to supplant state of the art alternatives. Mission potential includes doubling science payloads for reference missions, increasing targets for a Trojan tour, and enabling missions such as Ceres Sample Return.
Archetype-based semantic integration and standardization of clinical data.
Moner, David; Maldonado, Jose A; Bosca, Diego; Fernandez, Jesualdo T; Angulo, Carlos; Crespo, Pere; Vivancos, Pedro J; Robles, Montserrat
2006-01-01
One of the basic needs for any healthcare professional is to be able to access to clinical information of patients in an understandable and normalized way. The lifelong clinical information of any person supported by electronic means configures his/her Electronic Health Record (EHR). This information is usually distributed among several independent and heterogeneous systems that may be syntactically or semantically incompatible. The Dual Model architecture has appeared as a new proposal for maintaining a homogeneous representation of the EHR with a clear separation between information and knowledge. Information is represented by a Reference Model which describes common data structures with minimal semantics. Knowledge is specified by archetypes, which are formal representations of clinical concepts built upon a particular Reference Model. This kind of architecture is originally thought for implantation of new clinical information systems, but archetypes can be also used for integrating data of existing and not normalized systems, adding at the same time a semantic meaning to the integrated data. In this paper we explain the possible use of a Dual Model approach for semantic integration and standardization of heterogeneous clinical data sources and present LinkEHR-Ed, a tool for developing archetypes as elements for integration purposes. LinkEHR-Ed has been designed to be easily used by the two main participants of the creation process of archetypes for clinical data integration: the Health domain expert and the Information Technologies domain expert.
Anthropomorphic Telemanipulation System in Terminus Control Mode
NASA Technical Reports Server (NTRS)
Jau, Bruno M.; Lewis, M. Anthony; Bejczy, Antal K.
1994-01-01
This paper describes a prototype anthropomorphic kinesthetic telepresence system that is being developed at JPL. It utilizes dexterous terminus devices in the form of an exoskeleton force-sensing master glove worn by the operator and a replica four finger anthropomorphic slave hand. The newly developed master glove is integrated with our previously developed non-anthropomorphic six degree of freedom (DOF) universal force-reflecting hand controller (FRHC). The mechanical hand and forearm are mounted to an industrial robot (PUMA 560), replacing its standard forearm. The notion of 'terminus control mode' refers to the fact that only the terminus devices (glove and robot hand) are of anthropomorphic nature, and the master and slave arms are non-anthropomorphic. The system is currently being evaluated, focusing on tool handling and astronaut equivalent task executions. The evaluation revealed the system's potential for tool handling but it also became evident that hand tool manipulations and space operations require a dual arm robot. This paper describes the system's principal components, its control and computing architecture, discusses findings of the tool handling evaluation, and explains why common tool handling and EVA space tasks require dual arm robots.
Gaeta, Michele; Scribano, Emanuele; Mileto, Achille; Mazziotti, Silvio; Rodolico, Carmelo; Toscano, Antonio; Settineri, Nicola; Ascenti, Giorgio; Blandino, Alfredo
2011-05-01
To prospectively evaluate the muscle fat fraction (MFF) measured with dual-echo dual-flip-angle spoiled gradient-recalled acquisition in the steady state (SPGR) magnetic resonance (MR) imaging technique by using muscle biopsy as the reference standard. After ethics approval, written informed consent from all patients was obtained. Twenty-seven consecutive patients, evaluated at the Neuromuscular Disorders Center with a possible diagnosis of neuromuscular disorder, were prospectively studied with MR imaging of the lower extremities to quantify muscle fatty infiltration by means of MFF calculation. Spin-density- and T1-weighted fast SPGR in-phase and opposed-phase dual-echo sequences were performed, respectively, with 20° and 80° flip angles. Round regions of interest were drawn by consensus on selected MR sections corresponding to anticipated biopsy sites. These were marked on the patient's skin with a pen by using the infrared spider light of the system, and subsequent muscle biopsy was performed. MR images with regions of interest were stored on a secondary console where the MFF calculation was performed by another radiologist blinded to the biopsy results. MFFs calculated with dual-echo dual-flip-angle SPGR MR imaging and biopsy were compared by using a paired t test, Pearson correlation coefficient, and Bland-Altman plots. P value of < .05 was considered to indicate a statistically significant difference. The mean MFFs obtained with dual-echo dual-flip-angle SPGR MR imaging and biopsy were 20.3% (range, 1.7%-45.1%) and 20.6% (range, 3%-46.1%), respectively. The mean difference, standard deviation of the difference, and t value were -0.3, 1.3, and -1.3 (P > .2), respectively. The Pearson correlation coefficient was 0.995; with the Bland-Altman method, all data points were within the ± 2 SDs limits of agreement. The results show that dual-echo dual-flip-angle SPGR MR imaging technique provides reliable calculation of MFF, consistent with biopsy measurements. RSNA, 2011
Computational multiheterodyne spectroscopy
Burghoff, David; Yang, Yang; Hu, Qing
2016-01-01
Dual-comb spectroscopy allows for high-resolution spectra to be measured over broad bandwidths, but an essential requirement for coherent integration is the availability of a phase reference. Usually, this means that the combs’ phase and timing errors must be measured and either minimized by stabilization or removed by correction, limiting the technique’s applicability. We demonstrate that it is possible to extract the phase and timing signals of a multiheterodyne spectrum completely computationally, without any extra measurements or optical elements. These techniques are viable even when the relative linewidth exceeds the repetition rate difference and can tremendously simplify any dual-comb system. By reconceptualizing frequency combs in terms of the temporal structure of their phase noise, not their frequency stability, we can greatly expand the scope of multiheterodyne techniques. PMID:27847870
A bilayer Double Semion model with symmetry-enriched topological order
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ortiz, L., E-mail: lauraort@ucm.es; Martin-Delgado, M.A.
2016-12-15
We construct a new model of two-dimensional quantum spin systems that combines intrinsic topological orders and a global symmetry called flavour symmetry. It is referred as the bilayer Doubled Semion model (bDS) and is an instance of symmetry-enriched topological order. A honeycomb bilayer lattice is introduced to combine a Double Semion Topological Order with a global spin–flavour symmetry to get the fractionalization of its quasiparticles. The bDS model exhibits non-trivial braiding self-statistics of excitations and its dual model constitutes a Symmetry-Protected Topological Order with novel edge states. This dual model gives rise to a bilayer Non-Trivial Paramagnet that is invariantmore » under the flavour symmetry and the well-known spin flip symmetry.« less
Dual infections with different Legionella strains.
Wewalka, G; Schmid, D; Harrison, T G; Uldum, S A; Lück, C
2014-01-01
In 2010 a case of a dual infection with Legionella pneumophila serogroup (sg) 1 and sg 3 was identified by culture of a blood sample collected from a female Austrian patient with septic pneumonia. Subsequently all 35 European National Legionella Reference Laboratories were interviewed regarding the frequency of dual infections in legionellosis. The Reference Laboratories in Denmark, the UK and Germany reported the detection of another 14 cases of dual infections with different Legionella strains between 2002 and 2012. Among the 15 cases, there were four cases with different Legionella species, six cases with different L. pneumophila serogroups, and five cases of dual infections with L. pneumophila sg 1 with different MAb-types. The median age of the 15 cases was 56 years and the male to female ratio 1:1.14. Six of the 15 patients were receiving immunosuppressive treatment following organ transplantation (n = 3) or for underlying haematological and solid malignancies (n = 3). Five of the 15 cases died within 30 days following diagnosis. Efforts to detect dual infections with different Legionella strains will improve our ability to correctly elucidate the causative sources of infection and enhance our understanding of the epidemiology of Legionella infections. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.
ERIC Educational Resources Information Center
Makoe, Mpine
2018-01-01
Although education policies in many African countries refer to the need for distance education to widen participation in universities, they have not articulated guidelines on how they plan to develop systems and structures that will support it. The purpose of this study was to develop a policy framework specific for distance education provision in…
Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo
Davis, Scott C.; Samkoe, Kimberley S.; Tichauer, Kenneth M.; Sexton, Kristian J.; Gunn, Jason R.; Deharvengt, Sophie J.; Hasan, Tayyaba; Pogue, Brian W.
2013-01-01
The up-regulation of cell surface receptors has become a central focus in personalized cancer treatment; however, because of the complex nature of contrast agent pharmacokinetics in tumor tissue, methods to quantify receptor binding in vivo remain elusive. Here, we present a dual-tracer optical technique for noninvasive estimation of specific receptor binding in cancer. A multispectral MRI-coupled fluorescence molecular tomography system was used to image the uptake kinetics of two fluorescent tracers injected simultaneously, one tracer targeted to the receptor of interest and the other tracer a nontargeted reference. These dynamic tracer data were then fit to a dual-tracer compartmental model to estimate the density of receptors available for binding in the tissue. Applying this approach to mice with deep-seated gliomas that overexpress the EGF receptor produced an estimate of available receptor density of 2.3 ± 0.5 nM (n = 5), consistent with values estimated in comparative invasive imaging and ex vivo studies. PMID:23671066
Multi-species trace gas sensing with dual-wavelength QCLs
NASA Astrophysics Data System (ADS)
Hundt, P. Morten; Tuzson, Béla; Aseev, Oleg; Liu, Chang; Scheidegger, Philipp; Looser, Herbert; Kapsalidis, Filippos; Shahmohammadi, Mehran; Faist, Jérôme; Emmenegger, Lukas
2018-06-01
Instrumentation for environmental monitoring of gaseous pollutants and greenhouse gases tends to be complex, expensive, and energy demanding, because every compound measured relies on a specific analytical technique. This work demonstrates an alternative approach based on mid-infrared laser absorption spectroscopy with dual-wavelength quantum cascade lasers (QCLs). The combination of two dual- and one single-DFB QCL yields high-precision measurements of CO (0.08 ppb), CO2 (100 ppb), NH3 (0.02 ppb), NO (0.4 ppb), NO2 (0.1 ppb), N2O (0.045 ppb), and O3 (0.11 ppb) simultaneously in a compact setup (45 × 45 cm2). The lasers are driven time-multiplexed in intermittent continuous wave mode with a repetition rate of 1 kHz. The individual spectra are real-time averaged (1 s) by an FPGA-based data acquisition system. The instrument was assessed for environmental monitoring and benchmarked with reference instrumentation to demonstrate its potential for compact multi-species trace gas sensing.
Results of the 1995 JPL balloon flight solar cell calibration program
NASA Technical Reports Server (NTRS)
Anspaugh, B. E.; Weiss, R. S.
1995-01-01
The Jet Propulsion Laboratory (JPL) solar cell calibration program was conceived to produce reference standards for the purpose of accurately setting solar simulator intensities. The concept was to fly solar cells on a high-altitude balloon, to measure their output at altitudes near 120,000 ft (36.6 km), to recover the cells, and to use them as reference standards. The procedure is simple. The reference cell is placed in the simulator beam, and the beam intensity is adjusted until the reference cell reads the same as it read on the balloon. As long as the reference cell has the same spectral response as the cells or panels to be measured, this is a very accurate method of setting the intensity. But as solar cell technology changes, the spectral response of the solar cells changes also, and reference standards using the new technology must be built and calibrated. Until the summer of 1985, there had always been a question as to how much the atmosphere above the balloon modified the solar spectrum. If the modification was significant, the reference cells might not have the required accuracy. Solar cells made in recent years have increasingly higher blue responses, and if the atmosphere has any effect at all, it would be expected to modify the calibration of these newer blue cells much more so than for cells made in the past. JPL has been flying calibration standards on high-altitude balloons since 1963 and continues to organize a calibration balloon flight at least once a year. The 1995 flight was the 48th flight in this series. The 1995 flight incorporated 46 solar cell modules from 7 different participants. The payload included Si, amorphous Si, GaAs, GaAs/Ge, dual junction cells, top and bottom sections of dual junction cells, and a triple junction cell. A new data acquisition system was built for the balloon flights and flown for the first time on the 1995 flight. This system allows the measurement of current-voltage (I-V) curves for 20 modules in addition to measurement of modules with fixed loads as had been done in the past.
A study of the transmission characteristics of suppressor nozzles
NASA Technical Reports Server (NTRS)
Ahuja, K. K.; Salikuddin, M.; Burrin, R. H.; Plumbee, H. E., Jr.
1980-01-01
The internal noise radiation characteristics for a single stream 12 lobe 24 tube suppressor nozzle, and for a dual stream 36 chute suppressor nozzle were investigated. An equivalent single round conical nozzle and an equivalent coannular nozzle system were also tested to provide a reference for the two suppressors. The technique utilized a high voltage spark discharge as a noise source within the test duct which permitted separation of the incident, reflected and transmitted signals in the time domain. These signals were then Fourier transformed to obtain the nozzle transmission coefficient and the power transfer function. These transmission parameters for the 12 lobe, 24 tube suppressor nozzle and the reference conical nozzle are presented as a function of jet Mach number, duct Mach number polar angle and temperature. Effects of simulated forward flight are also considered for this nozzle. For the dual stream, 36 chute suppressor, the transmission parameters are presented as a function of velocity ratios and temperature ratios. Possible data for the equivalent coaxial nozzle is also presented. Jet noise suppression by these nozzles is also discussed.
Development of a Flow Injection Based High Frequency Dual Channel Quartz Crystal Microbalance
Liang, Jinxing; Zhang, Jing; Zhou, Wenxiang; Ueda, Toshitsugu
2017-01-01
When the quartz crystal microbalance (QCM) is used in liquid for adsorption or desorption monitoring based bio- or chemical sensing applications, the frequency shift is not only determined by the surface mass change, but also by the change of liquid characteristics, such as density and viscosity, which are greatly affected by the liquid environmental temperature. A monolithic dual-channel QCM is designed and fabricated by arranging two QCM resonators on one single chip for cancelling the fluctuation induced by environmental factors. In actual applications, one QCM works as a specific sensor by modifying with functional membranes and the other acts as a reference, only measuring the liquid property. The dual-channel QCM is designed with an inverted-mesa structure, aiming to realize a high frequency miniaturized chip and suppress the frequency interference between the neighbored QCM resonators. The key problem of dual-channel QCMs is the interference between two channels, which is influenced by the distance of adjacent resonators. The diameter of the reference electrode has been designed into several values in order to find the optimal parameter. Experimental results demonstrated that the two QCMs could vibrate individually and the output frequency stability and drift can be greatly improved with the aid of the reference QCM. PMID:28509851
Weare, Jonathan; Dinner, Aaron R.; Roux, Benoît
2016-01-01
A multiple time-step integrator based on a dual Hamiltonian and a hybrid method combining molecular dynamics (MD) and Monte Carlo (MC) is proposed to sample systems in the canonical ensemble. The Dual Hamiltonian Multiple Time-Step (DHMTS) algorithm is based on two similar Hamiltonians: a computationally expensive one that serves as a reference and a computationally inexpensive one to which the workload is shifted. The central assumption is that the difference between the two Hamiltonians is slowly varying. Earlier work has shown that such dual Hamiltonian multiple time-step schemes effectively precondition nonlinear differential equations for dynamics by reformulating them into a recursive root finding problem that can be solved by propagating a correction term through an internal loop, analogous to RESPA. Of special interest in the present context, a hybrid MD-MC version of the DHMTS algorithm is introduced to enforce detailed balance via a Metropolis acceptance criterion and ensure consistency with the Boltzmann distribution. The Metropolis criterion suppresses the discretization errors normally associated with the propagation according to the computationally inexpensive Hamiltonian, treating the discretization error as an external work. Illustrative tests are carried out to demonstrate the effectiveness of the method. PMID:26918826
Vakalis, Stergios; Caligiuri, Carlo; Moustakas, Konstantinos; Malamis, Dimitris; Renzi, Massimiliano; Baratieri, Marco
2018-03-12
There is a growing market demand for small-scale biomass gasifiers that is driven by the economic incentives and the legislative framework. Small-scale gasifiers produce a gaseous fuel, commonly referred to as producer gas, with relatively low heating value. Thus, the most common energy conversion systems that are coupled with small-scale gasifiers are internal combustion engines. In order to increase the electrical efficiency, the operators choose dual fuel engines and mix the producer gas with diesel. The Wiebe function has been a valuable tool for assessing the efficiency of dual fuel internal combustion engines. This study introduces a thermodynamic model that works in parallel with the Wiebe function and calculates the emissions of the engines. This "vis-à-vis" approach takes into consideration the actual conditions inside the cylinders-as they are returned by the Wiebe function-and calculates the final thermodynamic equilibrium of the flue gases mixture. This approach aims to enhance the operation of the dual fuel internal combustion engines by identifying the optimal operating conditions and-at the same time-advance pollution control and minimize the environmental impact.
R-parametrization and its role in classification of linear multivariable feedback systems
NASA Technical Reports Server (NTRS)
Chen, Robert T. N.
1988-01-01
A classification of all the compensators that stabilize a given general plant in a linear, time-invariant multi-input, multi-output feedback system is developed. This classification, along with the associated necessary and sufficient conditions for stability of the feedback system, is achieved through the introduction of a new parameterization, referred to as R-Parameterization, which is a dual of the familiar Q-Parameterization. The classification is made to the stability conditions of the compensators and the plant by themselves; and necessary and sufficient conditions are based on the stability of Q and R themselves.
A Low-Cost and Portable Dual-Channel Fiber Optic Surface Plasmon Resonance System.
Liu, Qiang; Liu, Yun; Chen, Shimeng; Wang, Fang; Peng, Wei
2017-12-04
A miniaturization and integration dual-channel fiber optic surface plasmon resonance (SPR) system was proposed and demonstrated in this paper. We used a yellow light-emitting diode (LED, peak wavelength 595 nm) and built-in web camera as a light source and detector, respectively. Except for the detection channel, one of the sensors was used as a reference channel to compensate nonspecific binding and physical absorption. We packaged the LED and surface plasmon resonance (SPR) sensors together, which are flexible enough to be applied to mobile devices as a compact and portable system. Experimental results show that the normalized intensity shift and refractive index (RI) of the sample have a good linear relationship in the RI range from 1.328 to 1.348. We used this sensor to monitor the reversible, specific interaction between lectin concanavalin A (Con A) and glycoprotein ribonuclease B (RNase B), which demonstrate its capabilities of specific identification and biochemical samples concentration detection. This sensor system has potential applications in various fields, such as medical diagnosis, public health, food safety, and environment monitoring.
The Orbiter camera payload system's large-format camera and attitude reference system
NASA Technical Reports Server (NTRS)
Schardt, B. B.; Mollberg, B. H.
1985-01-01
The Orbiter camera payload system (OCPS) is an integrated photographic system carried into earth orbit as a payload in the Space Transportation System (STS) Orbiter vehicle's cargo bay. The major component of the OCPS is a large-format camera (LFC), a precision wide-angle cartographic instrument capable of producing high-resolution stereophotography of great geometric fidelity in multiple base-to-height ratios. A secondary and supporting system to the LFC is the attitude reference system (ARS), a dual-lens stellar camera array (SCA) and camera support structure. The SCA is a 70 mm film system that is rigidly mounted to the LFC lens support structure and, through the simultaneous acquisition of two star fields with each earth viewing LFC frame, makes it possible to precisely determine the pointing of the LFC optical axis with reference to the earth nadir point. Other components complete the current OCPS configuration as a high-precision cartographic data acquisition system. The primary design objective for the OCPS was to maximize system performance characteristics while maintaining a high level of reliability compatible with rocket launch conditions and the on-orbit environment. The full OCPS configuration was launched on a highly successful maiden voyage aboard the STS Orbiter vehicle Challenger on Oct. 5, 1984, as a major payload aboard the STS-41G mission.
Assessing FAO-56 dual crop coefficients using eddy covariance flux partitioning
USDA-ARS?s Scientific Manuscript database
Current approaches to scheduling crop irrigation using reference evapotranspiration (ET0) recommend using a dual-coefficient approach using basal (Kcb) and soil (Ke) coefficients along with a stress coefficient (Ks) to model crop evapotranspiration (ETc), [e.g. ETc=(Ks*Kcb+Ke)*ET0]. However, determi...
Individual Differences in Dual Task Performance. Final Report.
ERIC Educational Resources Information Center
Lansman, Marcy; Hunt, Earl
This report summarizes the research results and provides a reference. The basic question addressed was, "Is performance on multi-component tasks predicted by performance on the individual components performed separately?" In the first series of experiments, a dual task involving memory and verbal processing components to predict a…
NASA Technical Reports Server (NTRS)
Meneghini, Robert; Kim, Hyokyung; Liao, Liang; Jones, Jeffrey A.; Kwiatkowski, John M.
2015-01-01
It has long been recognized that path-integrated attenuation (PIA) can be used to improve precipitation estimates from high-frequency weather radar data. One approach that provides an estimate of this quantity from airborne or spaceborne radar data is the surface reference technique (SRT), which uses measurements of the surface cross section in the presence and absence of precipitation. Measurements from the dual-frequency precipitation radar (DPR) on the Global Precipitation Measurement (GPM) satellite afford the first opportunity to test the method for spaceborne radar data at Ka band as well as for the Ku-band-Ka-band combination. The study begins by reviewing the basis of the single- and dual-frequency SRT. As the performance of the method is closely tied to the behavior of the normalized radar cross section (NRCS or sigma(0)) of the surface, the statistics of sigma(0) derived from DPR measurements are given as a function of incidence angle and frequency for ocean and land backgrounds over a 1-month period. Several independent estimates of the PIA, formed by means of different surface reference datasets, can be used to test the consistency of the method since, in the absence of error, the estimates should be identical. Along with theoretical considerations, the comparisons provide an initial assessment of the performance of the single- and dual-frequency SRT for the DPR. The study finds that the dual-frequency SRT can provide improvement in the accuracy of path attenuation estimates relative to the single-frequency method, particularly at Ku band.
Reference Letters and the Uninformed Business Educator: A U.S. Legal Perspective
ERIC Educational Resources Information Center
Compton, Nina; Albinsson, Pia A.
2013-01-01
While providing references to students, business professors have to meet dual demands of giving sincere references to prospective employers while avoiding any potential litigation claims of "defamation" and "violation of privacy" from the students. While the approach of providing bare minimum information may seem to mitigate…
1989-08-15
literature. The perovskites lanthanum gallate (LaGaO3) (see Reference 1) and lanthanum aluminate (LaAIO 3) (see Reference 2) provide a good lattice match to...reported to be significantly reduced in doped gallate substrates (e.g., La 0.95Gd 0.05GaO 3) (see Reference 5). Doping serves the dual role of
Singh, Vimal; Pfeuffer, Josef; Zhao, Tiejun; Ress, David
2018-04-01
High-resolution functional magnetic resonance imaging of human subcortical brain structures is challenging because of their deep location in the cranium, and their comparatively weak blood oxygen level dependent responses to strong stimuli. Magnetic resonance imaging data for subcortical brain regions exhibit both low signal-to-noise ratio and low functional contrast-to-noise ratio. To overcome these challenges, this work evaluates the use of dual-echo spiral variants that combine outward and inward trajectories. Specifically, in-in, in-out, and out-out combinations are evaluated. For completeness, single-echo spiral-in and parallel-receive-accelerated echo-planar-imaging sequences are also evaluated. Sequence evaluation was based on comparison of functional contrast-to-noise ratio within retinotopically predefined regions of interest. Superior colliculus was chosen as sample subcortical brain region because it exhibits a strong visual response. All sequences were compared relative to a single-echo spiral-out trajectory to establish a within-session reference. In superior colliculus, the dual-echo out-out outperformed the reference trajectory by 55% in contrast-to-noise ratio, while all other trajectories had performance similar to the reference. The sequences were also compared in early visual cortex. Here, both dual-echo spiral out-out and in-out outperformed the reference by ∼25%. Dual-echo spiral variants offer improved contrast-to-noise ratio performance for high-resolution imaging for both superior colliculus and cortex. Magn Reson Med 79:1931-1940, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.
Yang, Lingang; Cui, Chuanfeng; Wang, Lingzhi; Lei, Juying; Zhang, Jinlong
2016-07-27
The rational design and controlled synthesis of a smart device with flexibly tailored response ability is all along desirable for bioapplication but long remains a considerable challenge. Here, a pH-stimulated valve system with a visualized "on-off" mode is constructed through a dual-shell fluorescence resonance energy transfer (FRET) strategy. The dual shells refer to carbon dots and fluorescent molecules embedded polymethacrylic acid (F-PMAA) layers successively coating around a SiO2 core (ca. 120 nm), which play the roles as energy donor and acceptor, respectively. The total thickness of the dual-shell in the solid composite is ca. 10 nm. The priorities of this dual-shell FRET nanovalve stem from three facts: (1) the thin shell allows the formation of efficient FRET system without chemical bonding between energy donor and acceptor; (2) the maximum emission wavelength of CD layer is tunable in the range of 400-600 nm, thus providing a flexible energy donor for a wide variety of energy acceptors; (3) the outer F-PMAA shell with a pH-sensitive swelling-shrinking (on-off) behavior functions as a valve for regulating the FRET process. As such, a sensitive and stable pH ratiometric sensor with a working pH range of 3-6 has been built by simply encapsulating pH-responsive fluorescein isothiocyanate (FITC) into PMAA; a pH-dependent swelling-shrinking shuttle carrier with a finely controllable molecule-release behavior has been further fabricated using rhodamine B isothiocyanate (RBITC) as the energy donor and model guest molecule. Significantly, the controlled releasing process is visually self-monitorable.
Dual wavelength multiple-angle light scattering system for cryptosporidium detection
NASA Astrophysics Data System (ADS)
Buaprathoom, S.; Pedley, S.; Sweeney, S. J.
2012-06-01
A simple, dual wavelength, multiple-angle, light scattering system has been developed for detecting cryptosporidium suspended in water. Cryptosporidium is a coccidial protozoan parasite causing cryptosporidiosis; a diarrheal disease of varying severity. The parasite is transmitted by ingestion of contaminated water, particularly drinking-water, but also accidental ingestion of bathing-water, including swimming pools. It is therefore important to be able to detect these parasites quickly, so that remedial action can be taken to reduce the risk of infection. The proposed system combines multiple-angle scattering detection of a single and two wavelengths, to collect relative wavelength angle-resolved scattering phase functions from tested suspension, and multivariate data analysis techniques to obtain characterizing information of samples under investigation. The system was designed to be simple, portable and inexpensive. It employs two diode lasers (violet InGaN-based and red AlGaInP-based) as light sources and silicon photodiodes as detectors and optical components, all of which are readily available. The measured scattering patterns using the dual wavelength system showed that the relative wavelength angle-resolved scattering pattern of cryptosporidium oocysts was significantly different from other particles (e.g. polystyrene latex sphere, E.coli). The single wavelength set up was applied for cryptosporidium oocysts'size and relative refractive index measurement and differential measurement of the concentration of cryptosporidium oocysts suspended in water and mixed polystyrene latex sphere suspension. The measurement results showed good agreement with the control reference values. These results indicate that the proposed method could potentially be applied to online detection in a water quality control system.
The openEHR Java reference implementation project.
Chen, Rong; Klein, Gunnar
2007-01-01
The openEHR foundation has developed an innovative design for interoperable and future-proof Electronic Health Record (EHR) systems based on a dual model approach with a stable reference information model complemented by archetypes for specific clinical purposes.A team from Sweden has implemented all the stable specifications in the Java programming language and donated the source code to the openEHR foundation. It was adopted as the openEHR Java Reference Implementation in March 2005 and released under open source licenses. This encourages early EHR implementation projects around the world and a number of groups have already started to use this code. The early Java implementation experience has also led to the publication of the openEHR Java Implementation Technology Specification. A number of design changes to the specifications and important minor corrections have been directly initiated by the implementation project over the last two years. The Java Implementation has been important for the validation and improvement of the openEHR design specifications and provides building blocks for future EHR systems.
NASA Technical Reports Server (NTRS)
Livas, Jeffrey (Inventor); Thorpe, James I. (Inventor); Numata, Kenji (Inventor)
2011-01-01
A method and system for stabilizing a laser to a frequency reference with an adjustable offset. The method locks a sideband signal generated by passing an incoming laser beam through the phase modulator to a frequency reference, and adjusts a carrier frequency relative to the locked sideband signal by changing a phase modulation frequency input to the phase modulator. The sideband signal can be a single sideband (SSB), dual sideband (DSB), or an electronic sideband (ESB) signal. Two separate electro-optic modulators can produce the DSB signal. The two electro-optic modulators can be a broadband modulator and a resonant modulator. With a DSB signal, the method can introduce two sinusoidal phase modulations at the phase modulator. With ESB signals, the method can further drive the optical phase modulator with an electrical signal with nominal frequency OMEGA(sub 1) that is phase modulated at a frequency OMEGA(sub 2)
Normal range of hepatic fat fraction on dual- and triple-echo fat quantification MR in children.
Shin, Hyun Joo; Kim, Hyun Gi; Kim, Myung-Joon; Koh, Hong; Kim, Ha Yan; Roh, Yun Ho; Lee, Mi-Jung
2015-01-01
To evaluate hepatic fat fraction on dual- and triple-echo gradient-recalled echo MRI sequences in healthy children. We retrospectively reviewed the records of children in a medical check-up clinic from May 2012 to November 2013. We excluded children with abnormal laboratory findings or those who were overweight. Hepatic fat fraction was measured on dual- and triple-echo sequences using 3T MRI. We compared fat fractions using the Wilcoxon signed rank test and the Bland-Altman 95% limits of agreement. The correlation between fat fractions and clinical and laboratory findings was evaluated using Spearman's correlation test, and the cut-off values of fat fractions for diagnosing fatty liver were obtained from reference intervals. In 54 children (M:F = 26:28; 5-15 years; mean 9 years), the dual fat fraction (0.1-8.0%; median 1.6%) was not different from the triple fat fraction (0.4-6.5%; median 2.7%) (p = 0.010). The dual- and triple-echo fat fractions showed good agreement using a Bland-Altman plot (-0.6 ± 2.8%). Eight children (14.8%) on dual-echo sequences and six (11.1%) on triple-echo sequences had greater than 5% fat fraction. From these children, six out of eight children on dual-echo sequences and four out of six children on triple-echo sequences had a 5-6% hepatic fat fraction. When using a cut-off value of a 6% fat fraction derived from a reference interval, only 3.7% of children were diagnosed with fatty liver. There was no significant correlation between clinical and laboratory findings with dual and triple-echo fat fractions. Dual fat fraction was not different from triple fat fraction. We suggest a cut-off value of a 6% fat fraction is more appropriate for diagnosing fatty liver on both dual- and triple-echo sequences in children.
Desse, Jean-Michel; Olchewsky, François
2018-04-15
This Letter proposes a dual-reference digital holographic interferometer for analyzing the high refractive index encountered in transonic and supersonic flows. For that, a Wollaston prism is inserted in the reference arm in order to simultaneously generate two orthogonally polarized reference waves. As a consequence, recorded interferograms contain two crossed and perpendicular interference patterns that give two orders fully separated in the Fourier spectrum. It is then possible to analyze a transparent object regardless of the orientation of the refractive index gradient using the two phase maps reconstructed with each of the two first interference orders. Fusion of the phase maps yields a single phase map in which the phase singularities are removed. Experimental results demonstrate the suitability of the proposed approach for analyzing shock waves in the unsteady wake flow around a circular cylinder at Mach 0.75.
NASA Astrophysics Data System (ADS)
Boudousq, V.; Bordy, T.; Gonon, G.; Dinten, J. M.
2005-04-01
The LEXXOS (DMS, Montpellier, France) is the first axial and total body cone beam bone densitometer using a 2D digital radiographic detector. Technical principles and performances for BMD measurements have been presented in previous papers. Bone densitometers are also used on small animals for drug development. In this paper, we show how the LEXXOS system can be adapted to small animals examinations, and its performances are evaluated. At first, in order to take advantage of the whole area of the digital flat panel X-ray detector, the geometrical configuration has been adapted. Secondly, as small animals present low BMD, a specific dual energy calibration has been defined. This adapted system has then been evaluated on two sets of mice: six reference mice and six ovariectomized mice. Each month, these two populations have been examined and the total body BMD has been measured. This evaluation has shown that the right order of BMD magnitude has been obtained and, as expected, BMD increases on the two sets until age of puberty and after this period, decreases significantly for the ovariectomized set. Moreover, the bone image obtained by dual energy processing on LEXXOS presents a radiographic image quality providing with useful complementary information on bone morphometry and architecture.
Progress on a Multichannel, Dual-Mixer Stability Analyzer
NASA Technical Reports Server (NTRS)
Kirk, Albert; Cole, Steven; Stevens, Gary; Tucker, Blake; Greenhall, Charles
2005-01-01
Several documents describe aspects of the continuing development of a multichannel, dual-mixer system for simultaneous characterization of the instabilities of multiple precise, low-noise oscillators. One of the oscillators would be deemed to be a reference oscillator, its frequency would be offset by an amount (100 Hz) much greater than the desired data rate, and each of the other oscillators would be compared with the frequency-offset signal by operation of a combination of hardware and software. A high-rate time-tag counter would collect zero-crossing times of the approximately equal 100-Hz beat notes. The system would effect a combination of interpolation and averaging to process the time tags into low-rate phase residuals at the desired grid times. Circuitry that has been developed since the cited prior article includes an eight-channel timer board to replace an obsolete commercial time-tag counter, plus a custom offset generator, cleanup loop, distribution amplifier, zero-crossing detector, and frequency divider.
NASA Technical Reports Server (NTRS)
Maleki, Lutfollah (Inventor)
1993-01-01
Two different carrier frequencies modulated by a reference frequency are transmitted to each receiver to be synchronized therewith. Each receiver responds to local phase differences between the two received signals to correct the phase of one of them so as to maintain the corrected signal as a reliable synchronization reference.
Rhee, Ye-Kyu; Huh, Yoon-Hyuk; Cho, Lee-Ra; Park, Chan-Jin
2015-12-01
The aim of this study is to evaluate the appropriate impression technique by analyzing the superimposition of 3D digital model for evaluating accuracy of conventional impression technique and digital impression. Twenty-four patients who had no periodontitis or temporomandibular joint disease were selected for analysis. As a reference model, digital impressions with a digital impression system were performed. As a test models, for conventional impression dual-arch and full-arch, impression techniques utilizing addition type polyvinylsiloxane for fabrication of cast were applied. 3D laser scanner is used for scanning the cast. Each 3 pairs for 25 STL datasets were imported into the inspection software. The three-dimensional differences were illustrated in a color-coded map. For three-dimensional quantitative analysis, 4 specified contact locations(buccal and lingual cusps of second premolar and molar) were established. For twodimensional quantitative analysis, the sectioning from buccal cusp to lingual cusp of second premolar and molar were acquired depending on the tooth axis. In color-coded map, the biggest difference between intraoral scanning and dual-arch impression was seen (P<.05). In three-dimensional analysis, the biggest difference was seen between intraoral scanning and dual-arch impression and the smallest difference was seen between dual-arch and full-arch impression. The two- and three-dimensional deviations between intraoral scanner and dual-arch impression was bigger than full-arch and dual-arch impression (P<.05). The second premolar showed significantly bigger three-dimensional deviations than the second molar in the three-dimensional deviations (P>.05).
Rhee, Ye-Kyu
2015-01-01
PURPOSE The aim of this study is to evaluate the appropriate impression technique by analyzing the superimposition of 3D digital model for evaluating accuracy of conventional impression technique and digital impression. MATERIALS AND METHODS Twenty-four patients who had no periodontitis or temporomandibular joint disease were selected for analysis. As a reference model, digital impressions with a digital impression system were performed. As a test models, for conventional impression dual-arch and full-arch, impression techniques utilizing addition type polyvinylsiloxane for fabrication of cast were applied. 3D laser scanner is used for scanning the cast. Each 3 pairs for 25 STL datasets were imported into the inspection software. The three-dimensional differences were illustrated in a color-coded map. For three-dimensional quantitative analysis, 4 specified contact locations(buccal and lingual cusps of second premolar and molar) were established. For twodimensional quantitative analysis, the sectioning from buccal cusp to lingual cusp of second premolar and molar were acquired depending on the tooth axis. RESULTS In color-coded map, the biggest difference between intraoral scanning and dual-arch impression was seen (P<.05). In three-dimensional analysis, the biggest difference was seen between intraoral scanning and dual-arch impression and the smallest difference was seen between dual-arch and full-arch impression. CONCLUSION The two- and three-dimensional deviations between intraoral scanner and dual-arch impression was bigger than full-arch and dual-arch impression (P<.05). The second premolar showed significantly bigger three-dimensional deviations than the second molar in the three-dimensional deviations (P>.05). PMID:26816576
Dual-Use system architecture for a space situational awareness system in Japan
NASA Astrophysics Data System (ADS)
Otani, Y.; Kohtake, N.; Ohkami, Y.
The use of outer space plays a vital role in both defense and civil fields. Since the separation of space activities between civil and defense applications is extremely inefficient, the Dual-Use concept has been considered fundamental for promoting the effective use of space. To the best of the authors' knowledge, most previous studies on Dual-Use focused on the technological aspects, and very few on a system engineering approach to Dual-Use. This left some important issues untouched such as the operational aspects of a system of systems, which need to be understood in a more generic context. This paper presents the results of a conceptual study, system design and management analysis of Dual-Use system architecture. First, an outline of the Dual-Use concept will be described and a definition of Dual-Use given. The effectiveness of applying the Dual-Use system concept to Space Situational Awareness (SSA) for both defense and civil users as a system of systems will then be discussed and investigated with a stakeholders analysis, context diagram and design structure matrix method. It has demonstrated that there is a need for a Dual-Use SSA Data Center which works as a binder between defense and civil systems as well as a data policy for constructing a Dual-Use SSA system.
Dual Mission Scenarios for the Human Lunar Campaign - Performance, Cost and Risk Benefits
NASA Technical Reports Server (NTRS)
Saucillo, Rudolph J.; Reeves, David M.; Chrone, Jonathan D.; Stromgren, Chel; Reeves, John D.; North, David D.
2008-01-01
Scenarios for human lunar operations with capabilities significantly beyond Constellation Program baseline missions are potentially feasible based on the concept of dual, sequential missions utilizing a common crew and a single Ares I/CEV (Crew Exploration Vehicle). For example, scenarios possible within the scope of baseline technology planning include outpost-based sortie missions and dual sortie missions. Top level cost benefits of these dual sortie scenarios may be estimated by comparison to the Constellation Program reference two-mission-per-year lunar campaign. The primary cost benefit is the accomplishment of Mission B with a "single launch solution" since no Ares I launch is required. Cumulative risk to the crew is lowered since crew exposure to launch risks and Earth return risks are reduced versus comparable Constellation Program reference two-mission-per-year scenarios. Payload-to-the-lunar-surface capability is substantially increased in the Mission B sortie as a result of additional propellant available for Lunar Lander #2 descent. This additional propellant is a result of EDS #2 transferring a smaller stack through trans-lunar injection and using remaining propellant to perform a portion of the lunar orbit insertion (LOI) maneuver. This paper describes these dual mission concepts, including cost, risk and performance benefits per lunar sortie site, and provides an initial feasibility assessment.
Thomas, Christoph; Heuschmid, Martin; Schilling, David; Ketelsen, Dominik; Tsiflikas, Ilias; Stenzl, Arnulf; Claussen, Claus D; Schlemmer, Heinz-Peter
2010-11-01
To retrospectively evaluate radiation dose, image quality, and the ability to differentiate urinary calculi of differing compositions by using low-dose dual-energy computed tomography (CT). The institutional review board approved this retrospective study; informed consent was waived. A low-dose dual-energy CT protocol (tube voltage and reference effective tube current-time product, 140 kV and 23 mAs and 80 kV and 105 mAs; collimation, 64 × 0.6 mm; pitch, 0.7) for the detection of urinary calculi was implemented into routine clinical care. All patients (n = 112) who were examined with this protocol from July 2008 to August 2009 were included. The composition of urinary calculi was assessed by using commercially available postprocessing software and was compared with results of the reference standard (ex vivo infrared spectroscopy) in 40 patients for whom the reference standard was available. Effective doses were calculated. Image quality was rated subjectively and objectively and was correlated with patient size expressed as body cross-sectional area at the level of acquisition by using Spearman correlation coefficients. One calcified concrement in the distal ureter of an obese patient was mistakenly interpreted as mixed calcified and uric acid. One struvite calculus was falsely interpreted as cystine. All other uric acid, cystine, and calcium-containing calculi were correctly identified by using dual-energy CT. The mean radiation dose was 2.7 mSv. The average image quality was rated as acceptable, with a decrease in image quality in larger patients. Low-dose unenhanced dual-source dual-energy CT can help differentiate between calcified, uric acid, and cystine calculi at a radiation dose comparable to that of conventional intravenous pyelography. Because of decreased image quality in obese patients, only nonobese patients should be examined with this protocol. © RSNA, 2010.
Comb-Resolved Dual-Comb Spectroscopy Stabilized by Free-Running Continuous-Wave Lasers
NASA Astrophysics Data System (ADS)
Kuse, Naoya; Ozawa, Akira; Kobayashi, Yohei
2012-11-01
We demonstrate dual-comb spectroscopy with relatively phase-locked two frequency combs, instead of frequency combs firmly fixed to the absolute frequency references. By stabilizing two beat frequencies between two mode-locked lasers at different wavelengths observed via free-running continuous-wave (CW) lasers, two combs are tightly phase locked to each other. The frequency noise of the CW lasers barely affects the performance of dual-comb spectroscopy because of the extremely fast common-mode noise rejection. Transform-limited comb-resolved dual-comb spectroscopy with a 6 Hz radio frequency linewidth is demonstrated by the use of Yb-fiber oscillators.
NASA Astrophysics Data System (ADS)
Feria, Erlan H.
2008-04-01
In this third of a multi-paper series the discovery of a space dual for the laws of motion is reported and named the laws of retention. This space-time duality in physics is found to inherently surface from a latency-information theory (LIT) that is treated in the first two papers of this multi-paper series. A motion-coder and a retention-coder are fundamental elements of a LIT's recognition-communication system. While a LIT's motion-coder addresses motion-time issues of knowledge motion, a LIT's retention-coder addresses retention-space issues of knowledge retention. For the design of a motion-coder, such as a modulation-antenna system, the laws of motion in physics are used while for the design of a retention-coder, such as a write/read memory, the newly advanced laws of retention can be used. Furthermore, while the laws of motion reflect a configuration of space certainty, the laws of retention reflect a passing of time uncertainty. Since the retention duals of motion concepts are too many to cover in a single publication, the discussion will be centered on the retention duals for Newton's Principia and the gravitational law, Coulomb's electrical law, Maxwell's equations, Einstein's relativity theory, quantum mechanics, and the uncertainty principle. Furthermore the retention duals will be illustrated with an uncharged and non-rotating black hole (UNBH). A UNBH is the retention dual of a vacuum since the UNBH and vacuum offer, from a theoretical perspective, the least resistance to knowledge retention and motion, respectively. Using this space-time duality insight it will be shown that the speed of light in a vacuum of c M=2.9979 x 10 8 meters/sec has a retention dual, herein called the pace of dark in a UNBH of c R=6.1123 x 10 63 secs/m 3 where 'pace' refers to the expected retention-time per retention-space for the 'dark' knowledge residing in a black hole.
Tichauer, K M; Samkoe, K S; Klubben, W S; Hasan, T; Pogue, B W
2012-01-01
The quantification of tumor molecular expression in vivo could have a significant impact for informing and monitoring immerging targeted therapies in oncology. Molecular imaging of targeted tracers can be used to quantify receptor expression in the form of a binding potential (BP) if the arterial input curve or a surrogate of it is also measured. However, the assumptions of the most common approaches (reference tissue models) may not be valid for use in tumors. In this study, the validity of reference tissue models is investigated for use in tumors experimentally and in simulations. Three different tumor lines were grown subcutaneously in athymic mice and the mice were injected with a mixture of an epidermal growth factor receptor- (EGFR-) targeted fluorescent tracer and an untargeted fluorescent tracer. A one-compartment plasma input model demonstrated that the transport kinetics of both tracers were significantly different between tumors and all potential reference tissues, and using the reference tissue model resulted in a theoretical underestimation in BP of 50 ± 37%. On the other hand, the targeted and untargeted tracers demonstrated similar transport kinetics, allowing a dual-tracer approach to be employed to accurately estimate binding potential (with a theoretical error of 0.23 ± 9.07%). These findings highlight the potential for using a dual-tracer approach to quantify receptor expression in tumors with abnormal hemodynamics, possibly to inform the choice or progress of molecular cancer therapies. PMID:23022732
Easterbrooks, Susan R; Handley, C Michele
The broad term pervasive developmental disorder (PPD) describes a set of symptoms that occur along a continuum of severity; these symptoms are often referred to as autism spectrum disorders (ASDs). Little is known about the incidence and prevalence of ASDs among students who are deaf or hard of hearing (DHH). Teachers of DHH students, who must work with individuals with dual diagnoses, are at a loss for guidance from the literature. The authors review the literature on ASDs (also referred to as PDD) within the DHH population, provide results of a single-subject study to reduce PDD-type behaviors in a child with hearing loss, and argue that teachers of students who are DHH must learn about practices associated with applied behavior analysis as an tool for intervening therapeutically with children with dual diagnoses of hearing loss plus an ASD.
An impedance bridge measuring the capacitance ratio in the high frequency range up to 1 MHz
NASA Astrophysics Data System (ADS)
Bee Kim, Dan; Kew Lee, Hyung; Kim, Wan-Seop
2017-02-01
This paper describes a 2-terminal-pair impedance bridge, measuring the capacitance ratio in the high frequency range up to 1 MHz. The bridge was configured with two voltage sources and a phase control unit which enabled the bridge balance by synchronizing the voltage sources with an enhanced phase resolution. Without employing the transformers such as inductive voltage divider, injection and detection transformers, etc, the bridge system is quite simple to set up, and the balance procedure is quick and easy. Using this dual-source coaxial bridge, the 1:1 and 10:1 capacitance ratios were measured with 1 pF-1 nF capacitors in the frequency range from 1 kHz to 1 MHz. The measurement values obtained by the dual-source bridge were then compared with reference values measured using a commercial precision capacitance bridge of AH2700A, the Z-matrix method developed by ourselves, and the 4-terminal-pair coaxial bridge by the Czech Metrological Institute. All the measurements agreed within the reference uncertainty range of an order of 10-6-10-5, proving the bridge ability as a trustworthy tool for measuring the capacitance ratio in the high frequency range.
NASA Technical Reports Server (NTRS)
Craft, D. William
1992-01-01
A facility for the precise calibration of mass fuel flowmeters and turbine flowmeters located at AMETEK Aerospace Products Inc., Wilmington, Massachusetts is described. This facility is referred to as the Test and Calibration System (TACS). It is believed to be the most accurate test facility available for the calibration of jet engine fuel density measurement. The product of the volumetric flow rate measurement and the density measurement, results in a true mass flow rate determination. A dual-turbine flowmeter was designed during this program. The dual-turbine flowmeter was calibrated on the TACS to show the characteristics of this type of flowmeter. An angular momentum flowmeter was also calibrated on the TACS to demonstrate the accuracy of a true mass flowmeter having a 'state-of-the-art' design accuracy.
Experimental results for a two-dimensional supersonic inlet used as a thrust deflecting nozzle
NASA Technical Reports Server (NTRS)
Johns, Albert L.; Burstadt, Paul L.
1984-01-01
Nearly all supersonic V/STOL aircraft concepts are dependent on the thrust deflecting capability of a nozzle. In one unique concept, referred to as the reverse flow dual fan, not only is there a thrust deflecting nozzle for the fan and core engine exit flow, but because of the way the propulsion system operates during vertical takeoff and landing, the supersonic inlet is also used as a thrust deflecting nozzle. This paper presents results of an experimental study to evaluate the performance of a supersonic inlet used as a thrust deflecting nozzle for this reverse flow dual fan concept. Results are presented in terms of nozzle thrust coefficient and thrust vector angle for a number of inlet/nozzle configurations. Flow visualization and nozzle exit flow survey results are also shown.
Multifunctional quantum dots and liposome complexes in drug delivery
Wang, Qi; Chao, Yimin
2018-01-01
Incorporating both diagnostic and therapeutic functions into a single nanoscale system is an effective modern drug delivery strategy. Combining liposomes with semiconductor quantum dots (QDs) has great potential to achieve such dual functions, referred to in this review as a liposomal QD hybrid system (L-QD). Here we review the recent literature dealing with the design and application of L-QD for advances in bio-imaging and drug delivery. After a summary of L-QD synthesis processes and evaluation of their properties, we will focus on their multifunctional applications, ranging from in vitro cell imaging to theranostic drug delivery approaches. PMID:28866655
Multifunctional quantum dots and liposome complexes in drug delivery.
Wang, Qi; Chao, Yi-Min
2017-09-03
Incorporating both diagnostic and therapeutic functions into a single nanoscale system is an effective modern drug delivery strategy. Combining liposomes with semiconductor quantum dots (QDs) has great potential to achieve such dual functions, referred to in this review as a liposomal QD hybrid system (L-QD). Here we review the recent literature dealing with the design and application of L-QD for advances in bio-imaging and drug delivery. After a summary of L-QD synthesis processes and evaluation of their properties, we will focus on their multifunctional applications, ranging from in vitro cell imaging to theranostic drug delivery approaches.
Dual motor drive vehicle speed synchronization and coordination control strategy
NASA Astrophysics Data System (ADS)
Huang, Hao; Tu, Qunzhang; Jiang, Chenming; Ma, Limin; Li, Pei; Zhang, Hongxing
2018-04-01
Multi-motor driven systems are more and more widely used in the field of electric engineering vehicles, as a result of the road conditions and the variable load of engineering vehicles, makes multi-motors synchronization coordinated control system as a key point of the development of the electric vehicle drive system. This paper based on electrical machinery transmission speed in the process of engineering vehicles headed for coordinated control problem, summarized control strategies at home and abroad in recent years, made analysis and comparison of the characteristics, finally discussed the trend of development of the multi-motor coordination control, provided a reference for synchronized control system research of electric drive engineering vehicles.
ERIC Educational Resources Information Center
Werner, S.; Stawski, M.
2012-01-01
Background: Dual diagnosis (DD) refers to the coexistence of intellectual disability and psychiatric disorder. In order to provide individuals with DD with adequate care, it is essential for mental health workers to have adequate knowledge and positive attitudes. These may be achieved through proper training. Aims: To summarise the available…
Dual Language Development and Disorders: A Handbook on Bilingualism and Second Language Learning
ERIC Educational Resources Information Center
Genesee, Fred; Paradis, Johanne; Crago, Martha B.
2004-01-01
This book dispels many myths about dual language development and answers key questions that might arise as you work with children and their parents. Student profiles, definitions of key terms, and "clinical implications" sections for selected chapters make this a valuable reference for in-practice SLPs and educators, an accessible resource for…
A dual-cavity ruby maser for the Ka-band link experiment
NASA Technical Reports Server (NTRS)
Shell, J.; Quinn, R. B.
1994-01-01
A 33.68-GHz dual-cavity ruby maser was built to support the Ka-Band Link Experiment (KABLE) conducted with the Mars Observer spacecraft. It has 25 dB of net gain and a 3-dB bandwidth of 85 MHz. Its noise temperature in reference to the cooled feedhorn aperture is 5 K.
Imboden, Mary T.; Swartz, Ann M.; Finch, Holmes W.; Harber, Matthew P.; Kaminsky, Leonard A.
2017-01-01
Body composition assessments commonly focus predominantly on fat mass, however lean mass (LM) measurements also provide useful information regarding clinical and nutritional status. LM measurements help predict health outcomes and diagnose sarcopenia, which has been associated with frailty. Dual energy x-ray absorptiometry (DXA) is an established technique used in clinical and research settings to assess body composition including total and regional LM. Currently, there are no reference values available that were derived from GE-Healthcare DXA systems directly for US adults for LM, LM index (LMI), percent LM (%LM), and appendicular lean mass index (ALMI) and it is known that whole-body and regional LM measures differ by DXA manufacturer. Objective To develop reference values by age and sex for LM measures using GE-Healthcare DXA systems. Methods A de-identified sample was obtained from Ball State University’s Clinical Exercise Physiology Laboratory and University of Wisconsin-Milwaukee’s Physical Activity & Health Research Laboratory. DXA scans of 2,076 women and 1,251 men were completed using a GE Lunar Prodigy or iDXA. Percentiles (%ile) were calculated for all variables of interest (LM, LMI, %LM, and ALMI) and a factorial ANOVA was used to assess differences for each variable between 10-year age groups and sex, as well as the interaction between age and sex. Results Men had higher mean total LM, %LM, LMI, and ALMI than women (p<0.01), across all age groups. All LM variables decreased significantly over the 5 decades in men, however in women only total LM, %LM, and ALMI decreased from the youngest to oldest age groups (p<0.01). Conclusion These reference values provide for a more accurate interpretation of GE-Healthcare DXA-derived LM measurements offering clinicians and researchers with an initial resource to aid in the early detection and assessment of LM deficits. PMID:28426779
Construction and application of a new dual-hybrid random phase approximation.
Mezei, Pál D; Csonka, Gábor I; Ruzsinszky, Adrienn; Kállay, Mihály
2015-10-13
The direct random phase approximation (dRPA) combined with Kohn-Sham reference orbitals is among the most promising tools in computational chemistry and applicable in many areas of chemistry and physics. The reason for this is that it scales as N(4) with the system size, which is a considerable advantage over the accurate ab initio wave function methods like standard coupled-cluster. dRPA also yields a considerably more accurate description of thermodynamic and electronic properties than standard density-functional theory methods. It is also able to describe strong static electron correlation effects even in large systems with a small or vanishing band gap missed by common single-reference methods. However, dRPA has several flaws due to its self-correlation error. In order to obtain accurate and precise reaction energies, barriers and noncovalent intra- and intermolecular interactions, we construct a new dual-hybrid dRPA (hybridization of exact and semilocal exchange in both the energy and the orbitals) and test the performance of this new functional on isogyric, isodesmic, hypohomodesmotic, homodesmotic, and hyperhomodesmotic reaction classes. We also use a test set of 14 Diels-Alder reactions, six atomization energies (AE6), 38 hydrocarbon atomization energies, and 100 reaction barrier heights (DBH24, HT-BH38, and NHT-BH38). For noncovalent complexes, we use the NCCE31 and S22 test sets. To test the intramolecular interactions, we use a set of alkane, cysteine, phenylalanine-glycine-glycine tripeptide, and monosaccharide conformers. We also discuss the delocalization and static correlation errors. We show that a universally accurate description of chemical properties can be provided by a large, 75% exact exchange mixing both in the calculation of the reference orbitals and the final energy.
Wang, Huai-Yung; Chi, Yu-Chieh; Lin, Gong-Ru
2016-08-08
A novel millimeter-wave radio over fiber (MMW-RoF) link at carrier frequency of 35-GHz is proposed with the use of remotely beating MMW generation from reference master and injected slave colorless laser diode (LD) carriers at orthogonally polarized dual-wavelength injection-locking. The slave colorless LD supports lasing one of the dual-wavelength master modes with orthogonal polarizations, which facilitates the single-mode direct modulation of the quadrature amplitude modulation (QAM) orthogonal frequency division multiplexing (OFDM) data. Such an injected single-carrier encoding and coupled dual-carrier transmission with orthogonal polarization effectively suppresses the cross-heterodyne mode-beating intensity noise, the nonlinear modulation (NLM) and four-wave mixing (FWM) sidemodes during injection locking and fiber transmission. In 25-km single-mode fiber (SMF) based wireline system, the dual-carrier under single-mode encoding provides baseband 24-Gbit/s 64-QAM OFDM transmission with an error vector magnitude (EVM) of 8.8%, a bit error rate (BER) of 3.7 × 10-3, a power penalty of <1.5 dB. After remotely self-beating for wireless transmission, the beat MMW carrier at 35 GHz can deliver the passband 16-QAM OFDM at 4 Gbit/s to show corresponding EVM and BER of 15.5% and 1.4 × 10-3, respectively, after 25-km SMF and 1.6-m free-space transmission.
Nondestructive detection of pork quality based on dual-band VIS/NIR spectroscopy
NASA Astrophysics Data System (ADS)
Wang, Wenxiu; Peng, Yankun; Li, Yongyu; Tang, Xiuying; Liu, Yuanyuan
2015-05-01
With the continuous development of living standards and the relative change of dietary structure, consumers' rising and persistent demand for better quality of meat is emphasized. Colour, pH value, and cooking loss are important quality attributes when evaluating meat. To realize nondestructive detection of multi-parameter of meat quality simultaneously is popular in production and processing of meat and meat products. The objectives of this research were to compare the effectiveness of two bands for rapid nondestructive and simultaneous detection of pork quality attributes. Reflectance spectra of 60 chilled pork samples were collected from a dual-band visible/near-infrared spectroscopy system which covered 350-1100 nm and 1000-2600 nm. Then colour, pH value and cooking loss were determined by standard methods as reference values. Standard normal variables transform (SNVT) was employed to eliminate the spectral noise. A spectrum connection method was put forward for effective integration of the dual-band spectrum to make full use of the whole efficient information. Partial least squares regression (PLSR) and Principal component analysis (PCA) were applied to establish prediction models using based on single-band spectrum and dual-band spectrum, respectively. The experimental results showed that the PLSR model based on dual-band spectral information was superior to the models based on single band spectral information with lower root means quare error (RMSE) and higher accuracy. The PLSR model based on dual-band (use the overlapping part of first band) yielded the best prediction result with correlation coefficient of validation (Rv) of 0.9469, 0.9495, 0.9180, 0.9054 and 0.8789 for L*, a*, b*, pH value and cooking loss, respectively. This mainly because dual-band spectrum can provide sufficient and comprehensive information which reflected the quality attributes. Data fusion from dual-band spectrum could significantly improve pork quality parameters prediction performance. The research also indicated that multi-band spectral information fusion has potential to comprehensively evaluate other quality and safety attributes of pork.
Gauge-gravity duality and the black hole interior.
Marolf, Donald; Polchinski, Joseph
2013-10-25
We present a further argument that typical black holes with field theory duals have firewalls at the horizon. This argument makes no reference to entanglement between the black hole and any distant system, and so is not evaded by identifying degrees of freedom inside the black hole with those outside. We also address the Einstein-Rosen=Einstein-Podolsky-Rosen conjecture of Maldacena and Susskind, arguing that the correlations in generic highly entangled states cannot be geometrized as a smooth wormhole.
46 CFR 111.05-29 - Dual voltage direct current systems.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Dual voltage direct current systems. Each dual voltage direct current system must have a suitably sensitive ground detection system which indicates current in the ground connection, has a range of at least... 46 Shipping 4 2010-10-01 2010-10-01 false Dual voltage direct current systems. 111.05-29 Section...
46 CFR 111.05-29 - Dual voltage direct current systems.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Dual voltage direct current systems. Each dual voltage direct current system must have a suitably sensitive ground detection system which indicates current in the ground connection, has a range of at least... 46 Shipping 4 2011-10-01 2011-10-01 false Dual voltage direct current systems. 111.05-29 Section...
Balazik, Matthew T.; Farrae, Daniel J.; Darden, Tanya L.; Garman, Greg C.
2017-01-01
Atlantic sturgeon (Acipenser oxyrinchus oxyrinchus, Acipenseridae) populations are currently at severely depleted levels due to historic overfishing, habitat loss, and pollution. The importance of biologically correct stock structure for effective conservation and management efforts is well known. Recent improvements in our understanding of Atlantic sturgeon migrations, movement, and the occurrence of putative dual spawning groups leads to questions regarding the true stock structure of this endangered species. In the James River, VA specifically, captures of spawning Atlantic sturgeon and accompanying telemetry data suggest there are two discrete spawning groups of Atlantic sturgeon. The two putative spawning groups were genetically evaluated using a powerful microsatellite marker suite to determine if they are genetically distinct. Specifically, this study evaluates the genetic structure, characterizes the genetic diversity, estimates effective population size, and measures inbreeding of Atlantic sturgeon in the James River. The results indicate that fall and spring spawning James River Atlantic sturgeon groups are genetically distinct (overall FST = 0.048, F’ST = 0.181) with little admixture between the groups. The observed levels of genetic diversity and effective population sizes along with the lack of detected inbreeding all indicated that the James River has two genetically healthy populations of Atlantic sturgeon. The study also demonstrates that samples from adult Atlantic sturgeon, with proper sample selection criteria, can be informative when creating reference population databases. The presence of two genetically-distinct spawning groups of Atlantic sturgeon within the James River raises concerns about the current genetic assignment used by managers. Other nearby rivers may also have dual spawning groups that either are not accounted for or are pooled in reference databases. Our results represent the second documentation of genetically distinct dual spawning groups of Atlantic sturgeon in river systems along the U.S. Atlantic coast, suggesting that current reference population database should be updated to incorporate both new samples and our increased understanding of Atlantic sturgeon life history. PMID:28686610
Dual-fuel, dual-throat engine preliminary analysis
NASA Technical Reports Server (NTRS)
Obrien, C. J.
1979-01-01
A propulsion system analysis of the dual fuel, dual throat engine for launch vehicle applications was conducted. Basic dual throat engine characterization data were obtained to allow vehicle optimization studies to be conducted. A preliminary baseline engine system was defined.
14 CFR 23.399 - Dual control system.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Dual control system. 23.399 Section 23.399 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Loads § 23.399 Dual control system. (a) Each dual control system must be designed to withstand the force...
14 CFR 23.399 - Dual control system.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Dual control system. 23.399 Section 23.399 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Loads § 23.399 Dual control system. (a) Each dual control system must be designed to withstand the force...
14 CFR 23.399 - Dual control system.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Dual control system. 23.399 Section 23.399 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Loads § 23.399 Dual control system. (a) Each dual control system must be designed to withstand the force...
14 CFR 23.399 - Dual control system.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Dual control system. 23.399 Section 23.399 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Loads § 23.399 Dual control system. (a) Each dual control system must be designed to withstand the force...
14 CFR 23.399 - Dual control system.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Dual control system. 23.399 Section 23.399 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Loads § 23.399 Dual control system. (a) Each dual control system must be designed to withstand the force...
Voyager Saturn encounter attitude and articulation control experience
NASA Technical Reports Server (NTRS)
Carlisle, G.; Hill, M.
1981-01-01
The Voyager attitude and articulation control system is designed for a three-axis stabilized spacecraft; it uses a biasable sun sensor and a Canopus Star Tracker (CST) for celestial control, as well as a dry inertial reference unit, comprised of three dual-axis dry gryos, for inertial control. A series of complex maneuvers was required during the first of two Voyager spacecraft encounters with Saturn (November 13, 1980); these maneuvers involved rotating the spacecraft simultaneously about two or three axes while maintaining accurate pointing of the scan platform. Titan and Saturn earth occulation experiments and a ring scattering experiment are described. Target motion compensation and the effects of celestial sensor interference are also considered. Failure of the CST, which required an extensive reevaluation of the star reference and attitude control mode strategy, is discussed. Results analyzed thus far show that the system performed with high accuracy, gathering data deeper into Saturn's atmosphere than on any previous planetary encounter.
Improved dual-loop detection system for collecting real-time truck data
DOT National Transportation Integrated Search
2005-02-01
The WSDOTs dual-loop detectors capability of measuring vehicle lengths makes the dual-loop detection system a potential real-time truck data source for freight movement study. However, a previous study found the WSDOT dual-loop detection system...
ERIC Educational Resources Information Center
Cridland, Elizabeth K.; Deane, Frank P.; Hsu, Ching-I; Kelly, Peter J.
2012-01-01
The co-occurrence of substance use and mental health problems, often referred to as dual diagnosis (DD), is increasingly recognised as commonplace within substance abuse treatment programs. Two-hundred and thirty-four individuals from 9 Australian Salvation Army drug and alcohol rehabilitation programs completed a 3-month post-discharge telephone…
Morency, Christina
2014-12-12
This file contains a list of relevant references on the Biot theory (forward and inverse approaches), the double-porosity and dual-permeability theory, and seismic wave propagation in fracture porous media, in RIS format, to approach seismic monitoring in a complex fractured porous medium such as Brady?s Geothermal Field.
Philosophical aspects of dual use technologies.
Pustovit, Svitlana V; Williams, Erin D
2010-03-01
The term dual use technologies refers to research and technology with the potential both to yield valuable scientific knowledge and to be used for nefarious purposes with serious consequences for public health or the environment. There are two main approaches to assessing dual use technologies: pragmatic and metaphysical. A pragmatic approach relies on ethical principles and norms to generate specific guidance and policy for dual use technologies. A metaphysical approach exhorts us to the deeper study of human nature, our intentions, goals, values ideals and social relations when considering dual use technology. Use of science and technology (S and T) is determined by two components of human nature: human intentions and choices. We have drawn a distinction between specific measures, goals and intentions with respect to technologies in order to show that moral judgment about technologies must precede their use. Understanding of our intentionality and values, and our moral ideals, as a measurable, tangible part of the real world is important for the prevention of any possible harm from S and T. In the context of dual use technologies, we stress the importance of three main understandings of human nature: vulnerability, responsibility and narrative identity. These can become a strong ontological "antidote" to technology's poisoning of modern man. Each new technology can be measured and compared with man's values, traditions and societal norms. This can be done bearing in mind the concept that human nature is not dualistic, but pluralistic. A system of ethical principles that includes the principles of good intentions, the correspondence of goals and means, the balancing of risks and benefits, simplicity, and contextuality, will help ensure that technologies are more humanistic and friendly to human beings.
Development of dual PZT transducers for reference-free crack detection in thin plate structures.
Sohn, Hoon; Kim, Seuno Bum
2010-01-01
A new Lamb-wave-based nondestructive testing (NDT) technique, which does not rely on previously stored baseline data, is developed for crack monitoring in plate structures. Commonly, the presence of damage is identified by comparing "current data" measured from a potentially damaged stage of a structure with "baseline data" previously obtained at the intact condition of the structure. In practice, structural defects typically take place long after collection of the baseline data, and the baseline data can be also affected by external loading, temperature variations, and changing boundary conditions. To eliminate the dependence on the baseline data comparison, the authors previously developed a reference-free NDT technique using 2 pairs of collocated lead zirconate titanate (PZT) transducers placed on both sides of a plate. This reference-free technique is further advanced in the present study by the necessity of attaching transducers only on a single surface of a structure for certain applications such as aircraft. To achieve this goal, a new design of PZT transducers called dual PZT transducers is proposed. Crack formation creates Lamb wave mode conversion due to a sudden thickness change of the structure. This crack appearance is instantly detected from the measured Lamb wave signals using the dual PZT transducers. This study also suggests a reference-free statistical approach that enables damage classification using only the currently measured data set. Numerical simulations and experiments were conducted using an aluminum plate with uniform thickness and fundamental Lamb waves modes to demonstrate the applicability of the proposed technique to reference-free crack detection.
Dual-detection confocal fluorescence microscopy: fluorescence axial imaging without axial scanning.
Lee, Dong-Ryoung; Kim, Young-Duk; Gweon, Dae-Gab; Yoo, Hongki
2013-07-29
We propose a new method for high-speed, three-dimensional (3-D) fluorescence imaging, which we refer to as dual-detection confocal fluorescence microscopy (DDCFM). In contrast to conventional beam-scanning confocal fluorescence microscopy, where the focal spot must be scanned either optically or mechanically over a sample volume to reconstruct a 3-D image, DDCFM can obtain the depth of a fluorescent emitter without depth scanning. DDCFM comprises two photodetectors, each with a pinhole of different size, in the confocal detection system. Axial information on fluorescent emitters can be measured by the axial response curve through the ratio of intensity signals. DDCFM can rapidly acquire a 3-D fluorescent image from a single two-dimensional scan with less phototoxicity and photobleaching than confocal fluorescence microscopy because no mechanical depth scans are needed. We demonstrated the feasibility of the proposed method by phantom studies.
Wang, Xiaochen; Zhao, Xinhua; Peng, Chenrui; Zhang, Xinbo; Wang, Jianghai
2013-01-01
The objectives of this study are to investigate the impact of different factors on the nutrient pollutant concentrations in green roof runoff and to provide reference data for the engineering design of dual substrate layer green roofs. The data were collected from eight different trays under three kinds of artificial rains. The results showed that except for total phosphorus, dual substrate layer green roofs behaved as a sink for most of the nutrient pollutants (significant at p < 0.05), and the first-flush effect did not occur during the 27 simulated rain events. The results also revealed that the concentration of these nutrient pollutants in the runoff strongly depended on the features of the nutrient substrates used in the green roof and the depth of the adsorption substrates. Compared with the influence of the substrates, the influence of the plant density and drainage systems was small.
NASA Astrophysics Data System (ADS)
Yang, Qingchun; Wang, Hongxin; Chetehouna, Khaled; Gascoin, Nicolas
2017-01-01
The supersonic combustion ramjet (scramjet) engine remains the most promising airbreathing engine cycle for hypersonic flight, particularly the high-performance dual-mode scramjet in the range of flight Mach number from 4 to 7, because it can operates under different combustion modes. Isolator is a very key component of the dual-mode scramjet engine. In this paper, nonlinear characteristics of combustion mode transition is theoretically analyzed. The discontinuous sudden changes of static pressure and Mach number are obtained as the mode transition occurs, which emphasizing the importance of predication and control of combustion modes. In this paper, a predication model of different combustion modes is developed based on these these nonlinear features in the isolator flow field. it can provide a valuable reference for control system design of the scramjet-powered aerospace vehicle.
Muralikrishnan, Bala; Rachakonda, Prem; Lee, Vincent; Shilling, Meghan; Sawyer, Daniel; Cheok, Geraldine; Cournoyer, Luc
2017-12-01
Terrestrial laser scanners (TLS) are a class of 3D imaging systems that produce a 3D point cloud by measuring the range and two angles to a point. The fundamental measurement of a TLS is range. Relative range error is one component of the overall range error of TLS and its estimation is therefore an important aspect in establishing metrological traceability of measurements performed using these systems. Target geometry is an important aspect to consider when realizing the relative range tests. The recently published ASTM E2938-15 mandates the use of a plate target for the relative range tests. While a plate target may reasonably be expected to produce distortion free data even at far distances, the target itself needs careful alignment at each of the relative range test positions. In this paper, we discuss relative range experiments performed using a plate target and then address the advantages and limitations of using a sphere target. We then present a novel dual-sphere-plate target that draws from the advantages of the sphere and the plate without the associated limitations. The spheres in the dual-sphere-plate target are used simply as fiducials to identify a point on the surface of the plate that is common to both the scanner and the reference instrument, thus overcoming the need to carefully align the target.
The German Dual Apprenticeship System: An Analysis of Its Evolution and Present Challenges.
ERIC Educational Resources Information Center
Tremblay, Diane-Gabrielle; Le Bot, Irene
The evolution of Germany's dual apprenticeship system and the challenges now facing it were reviewed. The following topics were considered: (1) the progression from craft guilds to vocational training; (2) the history of Germany's dual apprenticeship system from its organization in the 1970s; (4) apprenticeship in the dual system; (3) Germany's…
Breast Tissue Characterization with Photon-counting Spectral CT Imaging: A Postmortem Breast Study
Ding, Huanjun; Klopfer, Michael J.; Ducote, Justin L.; Masaki, Fumitaro
2014-01-01
Purpose To investigate the feasibility of breast tissue characterization in terms of water, lipid, and protein contents with a spectral computed tomographic (CT) system based on a cadmium zinc telluride (CZT) photon-counting detector by using postmortem breasts. Materials and Methods Nineteen pairs of postmortem breasts were imaged with a CZT-based photon-counting spectral CT system with beam energy of 100 kVp. The mean glandular dose was estimated to be in the range of 1.8–2.2 mGy. The images were corrected for pulse pile-up and other artifacts by using spectral distortion corrections. Dual-energy decomposition was then applied to characterize each breast into water, lipid, and protein contents. The precision of the three-compartment characterization was evaluated by comparing the composition of right and left breasts, where the standard error of the estimations was determined. The results of dual-energy decomposition were compared by using averaged root mean square to chemical analysis, which was used as the reference standard. Results The standard errors of the estimations of the right-left correlations obtained from spectral CT were 7.4%, 6.7%, and 3.2% for water, lipid, and protein contents, respectively. Compared with the reference standard, the average root mean square error in breast tissue composition was 2.8%. Conclusion Spectral CT can be used to accurately quantify the water, lipid, and protein contents in breast tissue in a laboratory study by using postmortem specimens. © RSNA, 2014 PMID:24814180
The Goddard Space Flight Center (GSFC) robotics technology testbed
NASA Technical Reports Server (NTRS)
Schnurr, Rick; Obrien, Maureen; Cofer, Sue
1989-01-01
Much of the technology planned for use in NASA's Flight Telerobotic Servicer (FTS) and the Demonstration Test Flight (DTF) is relatively new and untested. To provide the answers needed to design safe, reliable, and fully functional robotics for flight, NASA/GSFC is developing a robotics technology testbed for research of issues such as zero-g robot control, dual arm teleoperation, simulations, and hierarchical control using a high level programming language. The testbed will be used to investigate these high risk technologies required for the FTS and DTF projects. The robotics technology testbed is centered around the dual arm teleoperation of a pair of 7 degree-of-freedom (DOF) manipulators, each with their own 6-DOF mini-master hand controllers. Several levels of safety are implemented using the control processor, a separate watchdog computer, and other low level features. High speed input/output ports allow the control processor to interface to a simulation workstation: all or part of the testbed hardware can be used in real time dynamic simulation of the testbed operations, allowing a quick and safe means for testing new control strategies. The NASA/National Bureau of Standards Standard Reference Model for Telerobot Control System Architecture (NASREM) hierarchical control scheme, is being used as the reference standard for system design. All software developed for the testbed, excluding some of simulation workstation software, is being developed in Ada. The testbed is being developed in phases. The first phase, which is nearing completion, and highlights future developments is described.
1976-04-15
System, Dual-System, Single-Mode, and Dual-Mode configurations. Tests were conducted to determine the feasibility of incorporating modular hardware on a...and 11-1/2 feet OFF-CENTER with the BAK-12 configured in the Single and Dual Mode to determine the effect of engaging the aircraft arresting-hook...cable OFF-CENTER. 90,000- pound deadload arrestments were conducted ON-CENTER in the Dual Mode to determine system performance with high-energy
A dual slope charge sampling analog front-end for a wireless neural recording system.
Lee, Seung Bae; Lee, Byunghun; Gosselin, Benoit; Ghovanloo, Maysam
2014-01-01
This paper presents a novel dual slope charge sampling (DSCS) analog front-end (AFE) architecture, which amplifies neural signals by taking advantage of the charge sampling concept for analog signal conditioning, such as amplification and filtering. The presented DSCS-AFE achieves amplification, filtering, and sampling in a simultaneous fashion, while consuming very small amount of power. The output of the DSCS-AFE produces a pulse width modulated (PWM) signal that is proportional to the input voltage amplitude. A circular shift register (CSR) utilizes time division multiplexing (TDM) of the PWM pulses to create a pseudo-digital TDM-PWM signal that can feed a wireless transmitter. The 8-channel system-on-a-chip was fabricated in a 0.35-μm CMOS process, occupying 2.4 × 2.1 mm(2) and consuming 255 μW from a 1.8V supply. Measured input-referred noise for the entire system, including the FPGA in order to recover PWM signal is 6.50 μV(rms) in the 288 Hz~10 kHz range. For each channel, sampling rate is 31.25 kHz, and power consumption is 31.8 μW.
Dual-channel (green and red) fluorescence microendoscope with subcellular resolution
NASA Astrophysics Data System (ADS)
de Paula D'Almeida, Camila; Fortunato, Thereza Cury; Teixeira Rosa, Ramon Gabriel; Romano, Renan Arnon; Moriyama, Lilian Tan; Pratavieira, Sebastião.
2018-02-01
Usually, tissue images at cellular level need biopsies to be done. Considering this, diagnostic devices, such as microendoscopes, have been developed with the purpose of do not be invasive. This study goal is the development of a dual-channel microendoscope, using two fluorescent labels: proflavine and protoporphyrin IX (PpIX), both approved by Food and Drug Administration. This system, with the potential to perform a microscopic diagnosis and to monitor a photodynamic therapy (PDT) session, uses a halogen lamp and an image fiber bundle to perform subcellular image. Proflavine fluorescence indicates the nuclei of the cell, which is the reference for PpIX localization on image tissue. Preliminary results indicate the efficacy of this optical technique to detect abnormal tissues and to improve the PDT dosimetry. This was the first time, up to our knowledge, that PpIX fluorescence was microscopically observed in vivo, in real time, combined to other fluorescent marker (Proflavine), which allowed to simultaneously observe the spatial localization of the PpIX in the mucosal tissue. We believe this system is very promising tool to monitor PDT in mucosa as it happens. Further experiments have to be performed in order to validate the system for PDT monitoring.
A Dual Slope Charge Sampling Analog Front-End for a Wireless Neural Recording System
Lee, Seung Bae; Lee, Byunghun; Gosselin, Benoit
2015-01-01
This paper presents a novel dual slope charge sampling (DSCS) analog front-end (AFE) architecture, which amplifies neural signals by taking advantage of the charge sampling concept for analog signal conditioning, such as amplification and filtering. The presented DSCS-AFE achieves amplification, filtering, and sampling in a simultaneous fashion, while consuming very small amount of power. The output of the DSCS-AFE produces a pulse width modulated (PWM) signal that is proportional to the input voltage amplitude. A circular shift register (CSR) utilizes time division multiplexing (TDM) of the PWM pulses to create a pseudo-digital TDM-PWM signal that can feed a wireless transmitter. The 8-channel system-on-a-chip was fabricated in a 0.35-µm CMOS process, occupying 2.4 × 2.1 mm2 and consuming 255 µW from a 1.8V supply. Measured input-referred noise for the entire system, including the FPGA in order to recover PWM signal is 6.50 µVrms in the 288 Hz~10 kHz range. For each channel, sampling rate is 31.25 kHz, and power consumption is 31.8 µW. PMID:25570655
NASA Technical Reports Server (NTRS)
Stutzman, Warren L.
1989-01-01
This paper reviews the effects of precipitation on earth-space communication links operating the 10 to 35 GHz frequency range. Emphasis is on the quantitative prediction of rain attenuation and depolarization. Discussions center on the models developed at Virginia Tech. Comments on other models are included as well as literature references to key works. Also included is the system level modeling for dual polarized communication systems with techniques for calculating antenna and propagation medium effects. Simple models for the calculation of average annual attenuation and cross-polarization discrimination (XPD) are presented. Calculation of worst month statistics are also presented.
ERIC Educational Resources Information Center
She, Hsiao-Ching
2002-01-01
Examines the process of students' conceptual changes with regard to air pressure and buoyancy as a result of teaching with the dual situated learning model. Uses a model designed according to the students' ontological viewpoint on science concepts as well as the nature of these concepts. (Contains 40 references.) (Author/YDS)
Improving Adolescent Judgment and Decision Making
Dansereau, Donald F.; Knight, Danica K.; Flynn, Patrick M.
2013-01-01
Human judgment and decision making (JDM) has substantial room for improvement, especially among adolescents. Increased technological and social complexity “ups the ante” for developing impactful JDM interventions and aids. Current explanatory advances in this field emphasize dual processing models that incorporate both experiential and analytic processing systems. According to these models, judgment and decisions based on the experiential system are rapid and stem from automatic reference to previously stored episodes. Those based on the analytic system are viewed as slower and consciously developed. These models also hypothesize that metacognitive (self-monitoring) activities embedded in the analytic system influence how and when the two systems are used. What is not included in these models is the development of an intersection between the two systems. Because such an intersection is strongly suggested by memory and educational research as the basis of wisdom/expertise, the present paper describes an Integrated Judgment and Decision-Making Model (IJDM) that incorporates this component. Wisdom/expertise is hypothesized to contain a collection of schematic structures that can emerge from the accumulation of similar episodes or repeated analytic practice. As will be argued, in comparisons to dual system models, the addition of this component provides a broader basis for selecting and designing interventions to improve adolescent JDM. Its development also has implications for generally enhancing cognitive interventions by adopting principles from athletic training to create automated, expert behaviors. PMID:24391350
Phase inverter provides variable reference push-pull output
NASA Technical Reports Server (NTRS)
1966-01-01
Dual-transistor difference amplifier provides a push-pull output referenced to a dc potential which can be varied without affecting the signal levels. The amplifier is coupled with a feedback circuit which can vary the operating points of the transistors by equal amounts to provide the variable reference potentials.
Anantharaman, Rahul; Peters, Thijs; Xing, Wen; Fontaine, Marie-Laure; Bredesen, Rune
2016-10-20
Dual phase membranes are highly CO 2 -selective membranes with an operating temperature above 400 °C. The focus of this work is to quantify the potential of dual phase membranes in pre- and post-combustion CO 2 capture processes. The process evaluations show that the dual phase membranes integrated with an NGCC power plant for CO 2 capture are not competitive with the MEA process for post-combustion capture. However, dual phase membrane concepts outperform the reference Selexol technology for pre-combustion CO 2 capture in an IGCC process. The two processes evaluated in this work, post-combustion NGCC and pre-combustion IGCC, represent extremes in CO 2 partial pressure fed to the separation unit. Based on the evaluations it is expected that dual phase membranes could be competitive for post-combustion capture from a pulverized coal fired power plant (PCC) and pre-combustion capture from an Integrated Reforming Cycle (IRCC).
Portable real-time color night vision
NASA Astrophysics Data System (ADS)
Toet, Alexander; Hogervorst, Maarten A.
2008-03-01
We developed a simple and fast lookup-table based method to derive and apply natural daylight colors to multi-band night-time images. The method deploys an optimal color transformation derived from a set of samples taken from a daytime color reference image. The colors in the resulting colorized multiband night-time images closely resemble the colors in the daytime color reference image. Also, object colors remain invariant under panning operations and are independent of the scene content. Here we describe the implementation of this method in two prototype portable dual band realtime night vision systems. One system provides co-aligned visual and near-infrared bands of two image intensifiers, the other provides co-aligned images from a digital image intensifier and an uncooled longwave infrared microbolometer. The co-aligned images from both systems are further processed by a notebook computer. The color mapping is implemented as a realtime lookup table transform. The resulting colorised video streams can be displayed in realtime on head mounted displays and stored on the hard disk of the notebook computer. Preliminary field trials demonstrate the potential of these systems for applications like surveillance, navigation and target detection.
46 CFR 129.326 - Dual-voltage generators.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Dual-voltage generators. 129.326 Section 129.326... INSTALLATIONS Power Sources and Distribution Systems § 129.326 Dual-voltage generators. If a dual-voltage generator is installed on an OSV— (a) The neutral of the dual-voltage system must be solidly grounded at the...
NASA Astrophysics Data System (ADS)
Sabol, John M.; Avinash, Gopal B.; Nicolas, Francois; Claus, Bernhard E. H.; Zhao, Jianguo; Dobbins, James T., III
2001-06-01
Dual-energy subtraction imaging increases the sensitivity and specificity of pulmonary nodule detection in chest radiography by reducing the contrast of overlying bone structures. Recent development of a fast, high-efficiency detector enables dual-energy imaging to be integrated into the traditional workflow. We have modified a GE RevolutionTM XQ/i chest imaging system to construct a dual-energy imaging prototype system. Here we describe the operating characteristics of this prototype and evaluate image quality. Empirical results show that the dual-energy CNR is maximized if the dose is approximately equal for both high and low energy exposures. Given the high detector DQE, and allocation of dose between the two views, we can acquire dual-energy PA and conventional lateral images with total dose equivalent to a conventional two-view film chest exam. Calculations have shown that the dual-exposure technique has superior CNR and tissue cancellation than single-exposure CR systems. Clinical images obtained on a prototype dual-energy imaging system show excellent tissue contrast cancellation, low noise, and modest motion artefacts. In summary, a prototype dual-energy system has been constructed which enables rapid, dual-exposure imaging of the chest using a commercially available high-efficiency, flat-panel x-ray detector. The quality of the clinical images generated with this prototype exceeds that of CR techniques and demonstrates the potential for improved detection and characterization of lung disease through dual-energy imaging.
The concreteness effect: evidence for dual coding and context availability.
Jessen, F; Heun, R; Erb, M; Granath, D O; Klose, U; Papassotiropoulos, A; Grodd, W
2000-08-01
The term concreteness effect refers to the observation that concrete nouns are processed faster and more accurately than abstract nouns in a variety of cognitive tasks. Two models have been proposed to explain the neuronal basis of the concreteness effect. The dual-coding theory attributes the advantage to the access of a right hemisphere image based system in addition to a verbal system by concrete words. The context availability theory argues that concrete words activate a broader contextual verbal support, which results in faster processing, but do not access a distinct image based system. We used event-related fMRI to detect the brain regions that subserve to the concreteness effect. We found greater activation in the lower right and left parietal lobes, in the left inferior frontal lobe and in the precuneus during encoding of concrete compared to abstract nouns. This makes a single exclusive theory unlikely and rather suggests a combination of both models. Superior encoding of concrete words in the present study may result from (1) greater verbal context resources reflected by the activation of left parietal and frontal associative areas, and (2) the additional activation of a non-verbal, perhaps spatial imagery-based system, in the right parietal lobe. Copyright 2000 Academic Press.
Abera, Goitom Gigar; Alemayehu, Yibeltal Kiflie; Herrin, Jeph
2017-11-10
Physicians who work in the private sector while also holding a salaried job in a public hospital, known as "dual practice," is one of the main retention strategies adopted by the government of Ethiopia. Dual practice was legally endorsed in Tigray National Regional State, Ethiopia in 2010. Therefore, the aim of this study was to explore the extent of dual practice, reasons why physicians engage in it, and its effects on public hospital services in this state in northern Ethiopia. A cross-sectional study using mixed methods was conducted from February to March 2011 in six geographically representative public hospitals of Tigray National Regional State. A semi-structured, self-administered questionnaire was distributed to all physicians working in the study hospitals, and an interviewer-administered, structured questionnaire was used to collect data from admitted patients. Focus group discussions were conducted with hospital governing boards. Quantitative and qualitative data were used in the analysis. Data were collected from 31 physicians and 449 patients in the six study hospitals. Six focus group discussions were conducted. Twenty-eight (90.3%) of the physicians were engaged in dual practice to some extent: 16 (51.6%) owned private clinics outside the public hospital, 5 (16.1%) worked part-time in outside private clinics, and 7 (22.6%) worked in the private wing of public hospitals. Income supplementation was the primary reason for engaging in dual practice, as reported by 100% of the physicians. The positive effects of dual practice from both managers' and physicians' perspectives were physician retention in the public sector. Ninety-one patients (20.3%) had been referred from a private clinic immediately prior to their current admission-a circular diversion pattern. Eighteen (19.8%) of the diverted patients reported that health workers in the public hospitals diverted them. Circular diversion pattern of referral system is the key negative consequence of dual practice. Physicians and hospital managers agreed that health worker retention was the main positive consequence of dual practice upon the public sector, and banning dual practice would result in a major loss of senior physicians. The motive behind the circular diversion pattern described by patients should be studied further.
Economic Efficiency and Investment Timing for Dual Water Systems
NASA Astrophysics Data System (ADS)
Leconte, Robert; Hughes, Trevor C.; Narayanan, Rangesan
1987-10-01
A general methodology to evaluate the economic feasibility of dual water systems is presented. In a first step, a static analysis (evaluation at a single point in time) is developed. The analysis requires the evaluation of consumers' and producer's surpluses from water use and the capital cost of the dual (outdoor) system. The analysis is then extended to a dynamic approach where the water demand increases with time (as a result of a population increase) and where the dual system is allowed to expand. The model determines whether construction of a dual system represents a net benefit, and if so, what is the best time to initiate the system (corresponding to maximization of social welfare). Conditions under which an analytic solution is possible are discussed and results of an application are summarized (including sensitivity to different parameters). The analysis allows identification of key parameters influencing attractiveness of dual water systems.
Men, Kuo; Dai, Jianrong; Chen, Xinyuan; Li, Minghui; Zhang, Ke; Huang, Peng
2017-04-01
To improve the image quality and accuracy of dose calculation for cone-beam computed tomography (CT) images through implementation of a dual-energy cone-beam computed tomography method (DE-CBCT), and evaluate the improvement quantitatively. Two sets of CBCT projections were acquired using the X-ray volumetric imaging (XVI) system on a Synergy (Elekta, Stockholm, Sweden) system with 120kV (high) and 70kV (low) X-rays, respectively. Then, the electron density relative to water (relative electron density (RED)) of each voxel was calculated using a projection-based dual-energy decomposition method. As a comparison, single-energy cone-beam computed tomography (SE-CBCT) was used to calculate RED with the Hounsfield unit-RED calibration curve generated by a CIRS phantom scan with identical imaging parameters. The imaging dose was measured with a dosimetry phantom. The image quality was evaluated quantitatively using a Catphan 503 phantom with the evaluation indices of the reproducibility of the RED values, high-contrast resolution (MTF 50% ), uniformity, and signal-to-noise ratio (SNR). Dose calculation of two simulated volumetric-modulated arc therapy plans using an Eclipse treatment-planning system (Varian Medical Systems, Palo Alto, CA, USA) was performed on an Alderson Rando Head and Neck (H&N) phantom and a Pelvis phantom. Fan-beam planning CT images for the H&N and Pelvis phantom were set as the reference. A global three-dimensional gamma analysis was used to compare dose distributions with the reference. The average gamma values for targets and OAR were analyzed with paired t-tests between DE-CBCT and SE-CBCT. In two scans (H&N scan and body scan), the imaging dose of DE-CBCT increased by 1.0% and decreased by 1.3%. It had a better reproducibility of the RED values (mean bias: 0.03 and 0.07) compared with SE-CBCT (mean bias: 0.13 and 0.16). It also improved the image uniformity (57.5% and 30.1%) and SNR (9.7% and 2.3%), but did not affect the MTF 50% . Gamma analyses of the 3D dose distribution with criteria of 1%/1mm showed a pass rate of 99.0-100% and 85.3-97.6% for DE-CBCT and 73.5-99.1% and 80.4-92.7% for SE-CBCT. The average gamma values were reduced significantly by DE-CBCT (p< 0.05). Gamma index maps showed that matching of the dose distribution between CBCT-based and reference was improved by DE-CBCT. DE-CBCT can achieve both better image quality and higher accuracy of dose calculation, and could be applied to adaptive radiotherapy. Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Ma, Chopo; MacMillan, Daniel; Gordon, David
2015-08-01
The Second Realization of the International Celestial Reference Frame (ICRF) used dual-frequency VLBI data acquired for geodetic and astrometric purposes from 1979-2009 by organizations now coordinated by the International VLBI Service for Geodesy and Astrometry (IVS) and analyzed according to the Conventions of the International Earth Rotation and Reference Systems Service (IERS). Since 2009 the data set has been significantly broadened, especially by observations in the Southern Hemisphere, and modeling of astronomical, geophysical and tropospheric effects has progressed. The new southern data appear to cause a systematic zonal declination change in the catalog positions. Over the three decades of the ICRF data set the effect of galactic aberration may be significant. Geophysical and tropospheric models also may affect the source positions. All these effects need to be addressed in preparation for ICRF-3.
Nonequilibrium thermodynamics of single DNA hairpins in a dual-trap optical tweezers setup
NASA Astrophysics Data System (ADS)
Crivellari, M. Ribezzi; Huguet, J. M.; Ritort, F.
2011-03-01
We use two counter propagating laser beams to create a dual trap optical tweezers setup which is free from cross interference between the beams and provides great instrumental stability. This setup works by direct measurement of light momentum, separately for each trap, and is based on the Minitweezers design [1]. The dual trap setup has many applications: it can be used to study the force-dependent unfolding kinetics of single molecules and to address fundamental problems in nonequilibrium thermodynamics of small systems [2]. Recent progress in statistical physics has shown the importance of considering large energy deviations in the beahvior of systems that are driven out-of-equilibrium by time-dependent forces. Prominent examples are nonequilibrium work relations (e.g. the Jarzynski equality [3]) and fluctuation theorems. By repeated measurement of the irreversible work the Jarzynski equality allows us to recover the free energy difference between two thermodynamic states, AF, by taking exponential averages of the work W done by the external agent on the system, e-βΔF =
1988-05-01
compensatory operations as a dual-mods control -- a form where the control exerted is Initiated and largely accomplished by the precognitive action and then...function. Fig. 3.2 Compensatory control structure for 4-7 precognitive operation occur in a "dual- quality criteria one is referred to mode" control... precognitive action Tesil itatieet rpoas f and then completed with compensatory error- mil quent ei to eure a reduction operations (Ref. 11). certary eqe mso
Ou, Huang-Tz; Chen, Yen-Ting; Liu, Ya-Ming; Wu, Jin-Shang
2016-06-01
To assess the cost-effectiveness of metformin-based dual therapies associated with cardiovascular disease (CVD) risk in a Chinese population with type 2 diabetes. We utilized Taiwan's National Health Insurance Research Database (NHIRD) 1997-2011, which is derived from the claims of National Health Insurance, a mandatory-enrollment single-payer system that covers over 99% of Taiwan's population. Four metformin-based dual therapy cohorts were used, namely a reference group of metformin plus sulfonylureas (Metformin-SU) and metformin plus acarbose, metformin plus thiazolidinediones (Metformin-TZD), and metformin plus glinides (Metformin-glinides). Using propensity scores, each subject in a comparison cohort was 1:1 matched to a referent. The effectiveness outcome was CVD risk. Only direct medical costs were included. The Markov chain model was applied to project lifetime outcomes, discounted at 3% per annum. The bootstrapping technique was performed to assess uncertainty in analysis. Metformin-glinides was most cost-effective in the base-case analysis; Metformin-glinides saved $194 USD for one percentage point of reduction in CVD risk, as compared to Metformin-SU. However, for the elderly or those with severe diabetic complications, Metformin-TZD, especially pioglitazone, was more suitable; as compared to Metformin-SU, Metformin-TZD saved $840.1 USD per percentage point of reduction in CVD risk. Among TZDs, Metformin-pioglitazone saved $1831.5 USD per percentage point of associated CVD risk reduction, as compared to Metformin-rosiglitazone. When CVD is considered an important clinical outcome, Metformin-pioglitazone is cost-effective, in particular for the elderly and those with severe diabetic complications. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Sohrabi, Mehdi; Parsi, Masoumeh; Sina, Sedigheh
2018-05-17
A diagnostic reference level is an advisory dose level set by a regulatory authority in a country as an efficient criterion for protection of patients from unwanted medical exposure. In computed tomography, the direct dose measurement and data collection methods are commonly applied for determination of diagnostic reference levels. Recently, a new quality-control-based dose survey method was proposed by the authors to simplify the diagnostic reference-level determination using a retrospective quality control database usually available at a regulatory authority in a country. In line with such a development, a prospective dual-purpose quality control dosimetry protocol is proposed for determination of diagnostic reference levels in a country, which can be simply applied by quality control service providers. This new proposed method was applied to five computed tomography scanners in Shiraz, Iran, and diagnostic reference levels for head, abdomen/pelvis, sinus, chest, and lumbar spine examinations were determined. The results were compared to those obtained by the data collection and quality-control-based dose survey methods, carried out in parallel in this study, and were found to agree well within approximately 6%. This is highly acceptable for quality-control-based methods according to International Atomic Energy Agency tolerance levels (±20%).
Analysis of Dual Mode Systems in an Urban Area : Volume 2. Study Results.
DOT National Transportation Integrated Search
1973-12-01
Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...
Analysis of Dual Mode Systems in an Urban Area : Volume 1. Summary.
DOT National Transportation Integrated Search
1973-12-01
Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...
Dual mode nuclear rocket system applications.
NASA Technical Reports Server (NTRS)
Boretz, J. E.; Bell, J. M.; Plebuch, R. K.; Priest, C. C.
1972-01-01
Mission areas where the dual-mode nuclear rocket system is superior to nondual-mode systems are demonstrated. It is shown that the dual-mode system is competitive with the nondual-mode system even for those specific missions and particular payload configurations where it does not have a clear-cut advantage.
A Competing Neurobehavioral Decision Systems Model of SES-Related Health and Behavioral Disparities
Bickel, W. K.; Moody, L.; Quisenberry, A. J.; Ramey, C. T.; Sheffer, C. E.
2014-01-01
We propose that executive dysfunction is an important component relating the socioeconomic status gradient of select health behaviors. We review and find evidence supporting an SES gradient associated with (1) negative health behaviors (e.g., obesity, excessive use of alcohol, tobacco and other substances), and (2) executive dysfunction. Moreover, the evidence supports that stress and insufficient cognitive resources contribute to executive dysfunction and that executive dysfunction is evident among individuals who smoke cigarettes, are obese, abuse alcohol, and use illicit drugs. Collectively these data supports the dual system model of cognitive control, referred to here as the Competing Neurobehavioral Decision Systems hypothesis. The implications of these relationships for intervention and social justice considerations are discussed. PMID:25008219
NASA Technical Reports Server (NTRS)
Mollberg, Bernard H.; Schardt, Bruton B.
1988-01-01
The Orbiter Camera Payload System (OCPS) is an integrated photographic system which is carried into earth orbit as a payload in the Space Transportation System (STS) Orbiter vehicle's cargo bay. The major component of the OCPS is a Large Format Camera (LFC), a precision wide-angle cartographic instrument that is capable of producing high resolution stereo photography of great geometric fidelity in multiple base-to-height (B/H) ratios. A secondary, supporting system to the LFC is the Attitude Reference System (ARS), which is a dual lens Stellar Camera Array (SCA) and camera support structure. The SCA is a 70-mm film system which is rigidly mounted to the LFC lens support structure and which, through the simultaneous acquisition of two star fields with each earth-viewing LFC frame, makes it possible to determine precisely the pointing of the LFC optical axis with reference to the earth nadir point. Other components complete the current OCPS configuration as a high precision cartographic data acquisition system. The primary design objective for the OCPS was to maximize system performance characteristics while maintaining a high level of reliability compatible with Shuttle launch conditions and the on-orbit environment. The full-up OCPS configuration was launched on a highly successful maiden voyage aboard the STS Orbiter vehicle Challenger on October 5, 1984, as a major payload aboard mission STS 41-G. This report documents the system design, the ground testing, the flight configuration, and an analysis of the results obtained during the Challenger mission STS 41-G.
Dual redundant arm system operational quality measures and their applications - Static measures
NASA Technical Reports Server (NTRS)
Lee, Sukhan; Kim, Sungbok
1990-01-01
The authors present dual-arm system static operational quality measures which quantify the efficiency and capability of a dual-arm system in generating Cartesian velocities and static forces. First, they define and analyze the kinematic interactions between the two arms incurred by the various modes of dual-arm cooperation, such as transport, assembly, and grasping modes of cooperation, and specify the kinematic constraints imposed on individual arms in Cartesian space due to the kinematic interactions. Dual-arm static manipulability is presented. Finally, dual-arm operational quality is scaled by a task-oriented operational quality measure (TOQs) obtained by the comparison between the desired and actual static manipulabilities. TOQs is used in the optimization of dual-arm joint configurations. Simulation results are shown.
Lin, Zhuchong; Liu, Kun; Zhang, Li; Zeng, Delin
2016-09-01
Maglev dual-stage inertially stabilization (MDIS) system is a newly proposed system which combines a conventional two-axis gimbal assembly and a 5-DOF (degree of freedom) magnetic bearing with vernier tilting capacity to perform dual-stage stabilization for the LOS of the suspended optical instrument. Compared with traditional dual-stage system, maglev dual-stage system exhibits different characteristics due to the negative position stiffness of the magnetic forces, which introduces additional coupling in the dual stage control system. In this paper, the coupling effect on the system performance is addressed based on frequency-domain analysis, including disturbance rejection, fine stage saturation and coarse stage structural resonance suppression. The difference between various control strategies is also discussed, including pile-up(PU), stabilize-follow (SF) and stabilize-compensate (SC). A number of principles for the design of a maglev dual stage system are proposed. A general process is also suggested, which leads to a cost-effective design striking a balance between high performance and complexity. At last, a simulation example is presented to illustrate the arguments in the paper. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.
Numata, Keiji; Yamazaki, Shoya; Naga, Naofumi
2012-05-14
We developed a facile and quick ethanol-based method for preparing silk nanoparticles and then fabricated a biodegradable and biocompatible dual-drug release system based on silk nanoparticles and the molecular networks of silk hydrogels. Model drugs incorporated in the silk nanoparticles and silk hydrogels showed fast and constant release, respectively, indicating successful dual-drug release from silk hydrogel containing silk nanoparticles. The release behaviors achieved by this dual-drug release system suggest to be regulated by physical properties (e.g., β-sheet contents and size of the silk nanoparticles and network size of the silk hydrogels), which is an important advantage for biomedical applications. The present silk-based system for dual-drug release also demonstrated no significant cytotoxicity against human mesenchymal stem cells (hMSCs), and thus, this silk-based dual-drug release system has potential as a versatile and useful new platform of polymeric materials for various types of dual delivery of bioactive molecules.
Machine learning-based dual-energy CT parametric mapping
NASA Astrophysics Data System (ADS)
Su, Kuan-Hao; Kuo, Jung-Wen; Jordan, David W.; Van Hedent, Steven; Klahr, Paul; Wei, Zhouping; Helo, Rose Al; Liang, Fan; Qian, Pengjiang; Pereira, Gisele C.; Rassouli, Negin; Gilkeson, Robert C.; Traughber, Bryan J.; Cheng, Chee-Wai; Muzic, Raymond F., Jr.
2018-06-01
The aim is to develop and evaluate machine learning methods for generating quantitative parametric maps of effective atomic number (Zeff), relative electron density (ρ e), mean excitation energy (I x ), and relative stopping power (RSP) from clinical dual-energy CT data. The maps could be used for material identification and radiation dose calculation. Machine learning methods of historical centroid (HC), random forest (RF), and artificial neural networks (ANN) were used to learn the relationship between dual-energy CT input data and ideal output parametric maps calculated for phantoms from the known compositions of 13 tissue substitutes. After training and model selection steps, the machine learning predictors were used to generate parametric maps from independent phantom and patient input data. Precision and accuracy were evaluated using the ideal maps. This process was repeated for a range of exposure doses, and performance was compared to that of the clinically-used dual-energy, physics-based method which served as the reference. The machine learning methods generated more accurate and precise parametric maps than those obtained using the reference method. Their performance advantage was particularly evident when using data from the lowest exposure, one-fifth of a typical clinical abdomen CT acquisition. The RF method achieved the greatest accuracy. In comparison, the ANN method was only 1% less accurate but had much better computational efficiency than RF, being able to produce parametric maps in 15 s. Machine learning methods outperformed the reference method in terms of accuracy and noise tolerance when generating parametric maps, encouraging further exploration of the techniques. Among the methods we evaluated, ANN is the most suitable for clinical use due to its combination of accuracy, excellent low-noise performance, and computational efficiency.
Machine learning-based dual-energy CT parametric mapping.
Su, Kuan-Hao; Kuo, Jung-Wen; Jordan, David W; Van Hedent, Steven; Klahr, Paul; Wei, Zhouping; Al Helo, Rose; Liang, Fan; Qian, Pengjiang; Pereira, Gisele C; Rassouli, Negin; Gilkeson, Robert C; Traughber, Bryan J; Cheng, Chee-Wai; Muzic, Raymond F
2018-06-08
The aim is to develop and evaluate machine learning methods for generating quantitative parametric maps of effective atomic number (Z eff ), relative electron density (ρ e ), mean excitation energy (I x ), and relative stopping power (RSP) from clinical dual-energy CT data. The maps could be used for material identification and radiation dose calculation. Machine learning methods of historical centroid (HC), random forest (RF), and artificial neural networks (ANN) were used to learn the relationship between dual-energy CT input data and ideal output parametric maps calculated for phantoms from the known compositions of 13 tissue substitutes. After training and model selection steps, the machine learning predictors were used to generate parametric maps from independent phantom and patient input data. Precision and accuracy were evaluated using the ideal maps. This process was repeated for a range of exposure doses, and performance was compared to that of the clinically-used dual-energy, physics-based method which served as the reference. The machine learning methods generated more accurate and precise parametric maps than those obtained using the reference method. Their performance advantage was particularly evident when using data from the lowest exposure, one-fifth of a typical clinical abdomen CT acquisition. The RF method achieved the greatest accuracy. In comparison, the ANN method was only 1% less accurate but had much better computational efficiency than RF, being able to produce parametric maps in 15 s. Machine learning methods outperformed the reference method in terms of accuracy and noise tolerance when generating parametric maps, encouraging further exploration of the techniques. Among the methods we evaluated, ANN is the most suitable for clinical use due to its combination of accuracy, excellent low-noise performance, and computational efficiency.
Wireless recording systems: from noninvasive EEG-NIRS to invasive EEG devices.
Sawan, Mohamad; Salam, Muhammad T; Le Lan, Jérôme; Kassab, Amal; Gelinas, Sébastien; Vannasing, Phetsamone; Lesage, Frédéric; Lassonde, Maryse; Nguyen, Dang K
2013-04-01
In this paper, we present the design and implementation of a wireless wearable electronic system dedicated to remote data recording for brain monitoring. The reported wireless recording system is used for a) simultaneous near-infrared spectrometry (NIRS) and scalp electro-encephalography (EEG) for noninvasive monitoring and b) intracerebral EEG (icEEG) for invasive monitoring. Bluetooth and dual radio links were introduced for these recordings. The Bluetooth-based device was embedded in a noninvasive multichannel EEG-NIRS system for easy portability and long-term monitoring. On the other hand, the 32-channel implantable recording device offers 24-bit resolution, tunable features, and a sampling frequency up to 2 kHz per channel. The analog front-end preamplifier presents low input-referred noise of 5 μ VRMS and a signal-to-noise ratio of 112 dB. The communication link is implemented using a dual-band radio frequency transceiver offering a half-duplex 800 kb/s data rate, 16.5 mW power consumption and less than 10(-10) post-correction Bit-Error Rate (BER). The designed system can be accessed and controlled by a computer with a user-friendly graphical interface. The proposed wireless implantable recording device was tested in vitro using real icEEG signals from two patients with refractory epilepsy. The wirelessly recorded signals were compared to the original signals recorded using wired-connection, and measured normalized root-mean square deviation was under 2%.
DOT National Transportation Integrated Search
1973-12-01
Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...
DOT National Transportation Integrated Search
1973-12-01
Various forms of Dual Mode transportation were analyzed in order to assess the economic viability of the dual mode concept. Specially designed new small Dual Mode vehicles, modifications of existing automobiles, and pallet systems, all operating in c...
NASA Astrophysics Data System (ADS)
Gooden, Matthew Edgell
A joint collaboration between the Triangle Universities Nuclear Laboratory (TUNL), Los Alamos National Laboratory (LANL) and Lawrence Livermore National Laboratory (LLNL) has performed a set of absolute Fission Product Yield (FPY) measurements. Using monoenergetic neutron at energies between 0.5 and 14.8 MeV, the excitation functions of a number of fission products from 235U, 238U and 239Pu have begun to be mapped out. This work has practical applications for the determination of weapon yields and the rate of burn-up in nuclear reactors, while also providing important insight into the fission process. Combining the use of a dual-fission ionization chamber and gamma-ray spectroscopy, absolute FPYs have been determined for approximately 15 different fission products. The dual-fission chamber is a back-to-back ionization chamber system with a 'thin' actinide foil in each chamber as a monitor or reference foil. The chamber holds a 'thick' target in the center of the system such that the target and reference foils are of the same actinide isotope. This allows for simple mass scaling between the recorded number of fissions in the individual chambers and the number of fissions in the center thick target, eliminating the need for the knowledge of the absolute fission cross section and its uncertainty. The 'thick' target was removed after activation and gamma-rays counted with well shielded High Purity Germanium (HPGe) detectors for a period of 1.5 - 2 months.
ATS-1/ATS-3 dual satellite navigation study
NASA Technical Reports Server (NTRS)
Hoover, W. M.
1971-01-01
A study which illustrated the feasibility of implementing an on-board aircraft navigation system based on using the ATS-1 and ATS-3 satellites, the modified Omega Position Location Equipment (OPLE) Control Center, and a suitable aircraft terminal was conducted. The report provides: (1) a consideration of the problems of satellite navigation and an objective definition of the optimum system under the constraints of its specified components, (2) a description of the necessary modifications to the OPLE Control Center, the design of an aircraft terminal, and the design of ground reference terminals, and (3) an outline of an experiment plan and an estimate of the cost to be expected in conducting the program.
D'estanque, Emmanuel; Hedon, Christophe; Lattuca, Benoît; Bourdon, Aurélie; Benkiran, Meriem; Verd, Aurélie; Roubille, François; Mariano-Goulart, Denis
2017-08-01
Dual-isotope 201 Tl/ 123 I-MIBG SPECT can assess trigger zones (dysfunctions in the autonomic nervous system located in areas of viable myocardium) that are substrate for ventricular arrhythmias after STEMI. This study evaluated the necessity of delayed acquisition and scatter correction for dual-isotope 201 Tl/ 123 I-MIBG SPECT studies with a CZT camera to identify trigger zones after revascularization in patients with STEMI in routine clinical settings. Sixty-nine patients were prospectively enrolled after revascularization to undergo 201 Tl/ 123 I-MIBG SPECT using a CZT camera (Discovery NM 530c, GE). The first acquisition was a single thallium study (before MIBG administration); the second and the third were early and late dual-isotope studies. We compared the scatter-uncorrected and scatter-corrected (TEW method) thallium studies with the results of magnetic resonance imaging or transthoracic echography (reference standard) to diagnose myocardial necrosis. Summed rest scores (SRS) were significantly higher in the delayed MIBG studies than the early MIBG studies. SRS and necrosis surface were significantly higher in the delayed thallium studies with scatter correction than without scatter correction, leading to less trigger zone diagnosis for the scatter-corrected studies. Compared with the scatter-uncorrected studies, the late thallium scatter-corrected studies provided the best diagnostic values for myocardial necrosis assessment. Delayed acquisitions and scatter-corrected dual-isotope 201 Tl/ 123 I-MIBG SPECT acquisitions provide an improved evaluation of trigger zones in routine clinical settings after revascularization for STEMI.
Okudan, Berna; Smitherman, Thomas C
2004-06-01
Myocardial perfusion scintigraphy is an established method in cardiology for the diagnosis and evaluation of coronary artery disease (CAD). Thallium-201 and Tc-99m sestamibi myocardial perfusion imaging has been widely accepted as non-invasive diagnostic procedure for detection of CAD, risk stratification and myocardial viability assessment. But, standard Tl-201 redistribution and same day or 2-day rest/stress Tc-99m sestamibi protocols are time-consuming. Hence, the dual isotope rest thallium-201/stress technetium-99m sestamibi gated single-photon emission tomography protocol has gained increasing popularity for these applications. Combining the use of thallium-201 with technetium-99m agents permits optimal image resolution and simultaneous assessment of viability. Dual-isotope imaging may be separate or simultaneous acquisition set-up. The more rapid completion of these studies is appreciated as an advantage by patients, technologists, interpreting and referring physicians, nurses and hospital management. Simultaneous imaging has the potential advantages of precise pixel registration and artifacts, if present, are identical in both thallium and sestamibi, and require only one set of imaging. Also, there are some disadvantages of spillover of activity from the Tc-99m to the Tl-201 window. Fortunately, despite this problem it can be overcome. Separate acquisition dual isotope also has some disadvantages. Difference in defect resolution in attenuation and scatter between T-201 and Tc-99m sestamibi potentially results in interpretation problems. But, studies about cost-effectiveness of dual isotope imaging showed that some selective elimination of the rest studies may decrease the cost of the nuclear procedures and should be considered in the current care health system.
Accelerating a MPEG-4 video decoder through custom software/hardware co-design
NASA Astrophysics Data System (ADS)
Díaz, Jorge L.; Barreto, Dacil; García, Luz; Marrero, Gustavo; Carballo, Pedro P.; Núñez, Antonio
2007-05-01
In this paper we present a novel methodology to accelerate an MPEG-4 video decoder using software/hardware co-design for wireless DAB/DMB networks. Software support includes the services provided by the embedded kernel μC/OS-II, and the application tasks mapped to software. Hardware support includes several custom co-processors and a communication architecture with bridges to the main system bus and with a dual port SRAM. Synchronization among tasks is achieved at two levels, by a hardware protocol and by kernel level scheduling services. Our reference application is an MPEG-4 video decoder composed of several software functions and written using a special C++ library named CASSE. Profiling and space exploration techniques were used previously over the Advanced Simple Profile (ASP) MPEG-4 decoder to determinate the best HW/SW partition developed here. This research is part of the ARTEMI project and its main goal is the establishment of methodologies for the design of real-time complex digital systems using Programmable Logic Devices with embedded microprocessors as target technology and the design of multimedia systems for broadcasting networks as reference application.
MacQueen, David A; Dalrymple, Savannah R; Drobes, David J; Diamond, David M
2016-06-01
Developed as a tool to assess working memory capacity in rodents, the odor span task (OST) has significant potential to advance drug discovery in animal models of psychiatric disorders. Prior investigations indicate OST performance is impaired by systemic administration of N-methyl-d-aspartate receptor (NMDA-r) antagonists and is sensitive to cholinergic manipulations. The present study sought to determine whether an impairment in OST performance can be produced by systemic administration of the competitive NMDA-r antagonist 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP; 3, 10, 17 mg/kg i.p.) in a unique dual-component variant of the OST, and whether this impairment is ameliorated by nicotine (0.75 mg/kg i.p.). Male Sprague-Dawley rats were trained to asymptotic level of performance on a 24-trial two-comparison incrementing nonmatching to sample OST. In addition, rats were administered a two-comparison olfactory reference memory (RM) task, which was integrated into the OST. The RM task provided an assessment of the effects of drug administration on global behavioral measures, long-term memory and motivation. Several measures of working memory (span, longest run, and accuracy) were dose dependently impaired by CPP without adversely affecting RM. Analysis of drug effects across trial blocks demonstrated a significant impairment of performance even at low memory loads, suggesting a CPP-induced deficit of olfactory short-term memory that is not load-dependent. Although nicotine did not ameliorate CPP-induced impairments in span or accuracy, it did block the impairment in longest run produced by the 10 mg/kg dose of CPP. Overall, our results indicate that performance in our 24 odor two-comparison OST is capacity dependent and that CPP impaired OST working, but not reference, memory. © 2016 MacQueen et al.; Published by Cold Spring Harbor Laboratory Press.
Dual-Modulation, Dual-Wavelength, Optical Polarimetry System for Glucose Monitoring
2016-08-26
dual-wavelength, optical polarimetry system for glucose monitoring 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) 5d...JBO.21.8.087001] 14. ABSTRACT A dual modulation optical polarimetry system utilizing both laser intensity and polarization modulation was designed...varying birefringence, which is one of the major limitations to the realization of polarimetry for glucose monitoring in the eye. The high-speed less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Huberts, Garlan J.; Qu, Qiuping; Czekala, Michael Damian
2017-03-28
A dual coil ignition system is provided. The dual coil ignition system includes a first inductive ignition coil including a first primary winding and a first secondary winding, and a second inductive ignition coil including a second primary winding and a second secondary winding, the second secondary winding connected in series to the first secondary winding. The dual coil ignition system further includes a diode network including a first diode and a second diode connected between the first secondary winding and the second secondary winding.
The Semigeostrophic Equations Discretized in Reference and Dual Variables
NASA Astrophysics Data System (ADS)
Cullen, Mike; Gangbo, Wilfrid; Pisante, Giovanni
2007-08-01
We study the evolution of a system of n particles {\\{(x_i, v_i)\\}_{i=1}n} in {mathbb{R}^{2d}} . That system is a conservative system with a Hamiltonian of the form {H[μ]=W22(μ, νn)} , where W 2 is the Wasserstein distance and μ is a discrete measure concentrated on the set {\\{(x_i, v_i)\\}_{i=1}n} . Typically, μ(0) is a discrete measure approximating an initial L ∞ density and can be chosen randomly. When d = 1, our results prove convergence of the discrete system to a variant of the semigeostrophic equations. We obtain that the limiting densities are absolutely continuous with respect to the Lebesgue measure. When {\\{ν^n\\}_{n=1}^infty} converges to a measure concentrated on a special d-dimensional set, we obtain the Vlasov-Monge-Ampère (VMA) system. When, d = 1 the VMA system coincides with the standard Vlasov-Poisson system.
Dual instrument for in vivo and ex vivo OCT imaging in an ENT department
Cernat, Ramona; Tatla, Taran S.; Pang, Jingyin; Tadrous, Paul J.; Bradu, Adrian; Dobre, George; Gelikonov, Grigory; Gelikonov, Valentin; Podoleanu, Adrian Gh.
2012-01-01
A dual instrument is assembled to investigate the usefulness of optical coherence tomography (OCT) imaging in an ear, nose and throat (ENT) department. Instrument 1 is dedicated to in vivo laryngeal investigation, based on an endoscope probe head assembled by compounding a miniature transversal flying spot scanning probe with a commercial fiber bundle endoscope. This dual probe head is used to implement a dual channel nasolaryngeal endoscopy-OCT system. The two probe heads are used to provide simultaneously OCT cross section images and en face fiber bundle endoscopic images. Instrument 2 is dedicated to either in vivo imaging of accessible surface skin and mucosal lesions of the scalp, face, neck and oral cavity or ex vivo imaging of the same excised tissues, based on a single OCT channel. This uses a better interface optics in a hand held probe. The two instruments share sequentially, the swept source at 1300 nm, the photo-detector unit and the imaging PC. An aiming red laser is permanently connected to the two instruments. This projects visible light collinearly with the 1300 nm beam and allows pixel correspondence between the en face endoscopy image and the cross section OCT image in Instrument 1, as well as surface guidance in Instrument 2 for the operator. The dual channel instrument was initially tested on phantom models and then on patients with suspect laryngeal lesions in a busy ENT practice. This feasibility study demonstrates the OCT potential of the dual imaging instrument as a useful tool in the testing and translation of OCT technology from the lab to the clinic. Instrument 1 is under investigation as a possible endoscopic screening tool for early laryngeal cancer. Larger size and better quality cross-section OCT images produced by Instrument 2 provide a reference base for comparison and continuing research on imaging freshly excised tissue, as well as in vivo interrogation of more superficial skin and mucosal lesions in the head and neck patient. PMID:23243583
NASA Astrophysics Data System (ADS)
Tian, Hongchun; Zhang, Sa; Hou, Zhiyun; Xia, Changming; Zhou, Guiyao; Zhang, Wei; Liu, Jiantao; Wu, Jiale; Fu, Jian
2016-06-01
A stable dual-wavelength ytterbium-doped photonic crystal fiber laser pumped by a 976 nm laser diode has been demonstrated at room temperature. Single-wavelength, dual-wavelength laser oscillations are observed when the fiber laser operates under different pump power by using different length of fibers. Stable dual-wavelength radiation around 1045 nm and 1075 nm has been generated simultaneously at a high pump power directly from an ytterbium-doped fiber laser without using any spectral control mechanism. A small core ytterbium-doped PCF fabricated by the powder sinter direction drawn rod technology is used as gain medium. The pump power and fiber length which can affect the output characteristics of dual-wavelength fiber laser are analyzed in the experiment. Experiments confirm that higher pump power and longer fiber length favors 1075 nm output; lower pump power and shorter fiber length favors 1045 nm output. Those results have a good reference in multi-wavelength fiber laser.
A dual-band reconfigurable Yagi-Uda antenna with diverse radiation patterns
NASA Astrophysics Data System (ADS)
Saurav, Kushmanda; Sarkar, Debdeep; Srivastava, Kumar Vaibhav
2017-07-01
In this paper, a dual-band pattern reconfigurable antenna is proposed. The antenna comprises of a dual-band complementary split ring resonators (CSRRs) loaded dipole as the driven element and two copper strips with varying lengths as parasitic segments on both sides of the driven dipole. PIN diodes are used with the parasitic elements to control their electrical length. The CSRRs loading provide a lower order mode in addition to the reference dipole mode, while the parasitic elements along with the PIN diodes are capable of switching the omni-directional radiation of the dual-band driven element to nine different configurations of radiation patterns which include bi-directional end-fire, broadside, and uni-directional end-fire in both the operating bands. A prototype of the designed antenna together with the PIN diodes and DC bias lines is fabricated to validate the concept of dual-band radiation pattern diversity. The simulation and measurement results are in good agreement. The proposed antenna can be used in wireless access points for PCS and WLAN applications.
Design of dual action antibiotics as an approach to search for new promising drugs
NASA Astrophysics Data System (ADS)
Tevyashova, A. N.; Olsufyeva, E. N.; Preobrazhenskaya, M. N.
2015-01-01
The review is devoted to the latest achievements in the design of dual action antibiotics — heterodimeric (chimeric) structures based on antibacterial agents of different classes (fluoroquinolones, anthracyclines, oxazolidines, macrolides and so on). Covalent binding can make the pharmacokinetic characteristics of these molecules more predictable and improve the penetration of each component into the cell. Consequently, not only does the drug efficacy increase owing to inhibition of two targets but also the resistance to one or both antibiotics can be overcome. The theoretical grounds of elaboration, design principles and methods for the synthesis of dual action antibiotics are considered. The structures are classified according to the type of covalent spacer (cleavable or not) connecting the moieties of two agents. Dual action antibiotics with a spacer that can be cleaved in a living cell are considered as dual action prodrugs. Data on the biological action of heterodimeric compounds are presented and structure-activity relationships are analyzed. The bibliography includes 225 references.
Dual-modality arterial pulse monitoring system for continuous blood pressure measurement.
Wen-Xuan Dai; Yuan-Ting Zhang; Jing Liu; Xiao-Rong Ding; Ni Zhao
2016-08-01
Accurate and ambulatory measurement of blood pressure (BP) is essential for efficient diagnosis, management and prevention of cardiovascular diseases (CVDs). However, traditional cuff-based BP measurement methods provide only intermittent BP readings and can cause discomfort with the occlusive cuff. Although pulse transit time (PTT) method is promising for cuffless and continuous BP measurement, its pervasive use is restricted by its limited accuracy and requirement of placing sensors on multiple body sites. To tackle these issues, we propose a novel dual-modality arterial pulse monitoring system for continuous blood pressure measurement, which simultaneously records the pressure and photoplethysmography (PPG) signals of radial artery. The obtained signals can be used to generate a pressure-volume curve, from which the elasticity index (EI) and viscosity index (VI) can be extracted. Experiments were carried out among 7 healthy subjects with their PPG, ECG, arterial pressure wave and reference BP collected to examine the effectiveness of the proposed indexes. The results of this study demonstrate that a linear regression model combining EI and VI has significantly higher BP tracking correlation coefficient as compared to the PTT method. This suggests that the proposed system and method can potentially be used for convenient and continuous blood pressure estimation with higher accuracy.
Evaluation of the Environmental Instruments, Incorporated Series 200 Dual Component Wind Set.
1980-09-01
elements is sensed to derive the sign (+ or -), which indicates the wind direction across the element pair. The reference arm of the Wheatstone bridge...Csine a for the crosswind axis, r and PF=a Vw Sine a for the headwind axis, r where Pa is the ambient air density, Pr is reference density at standard...pressure transducer is a hybrid linear silicon device which consists of a diaphragm and pressure reference , piezoresistive sensor, signal discriminator
Dynamic dual-tracer PET reconstruction.
Gao, Fei; Liu, Huafeng; Jian, Yiqiang; Shi, Pengcheng
2009-01-01
Although of important medical implications, simultaneous dual-tracer positron emission tomography reconstruction remains a challenging problem, primarily because the photon measurements from dual tracers are overlapped. In this paper, we propose a simultaneous dynamic dual-tracer reconstruction of tissue activity maps based on guidance from tracer kinetics. The dual-tracer reconstruction problem is formulated in a state-space representation, where parallel compartment models serve as continuous-time system equation describing the tracer kinetic processes of dual tracers, and the imaging data is expressed as discrete sampling of the system states in measurement equation. The image reconstruction problem has therefore become a state estimation problem in a continuous-discrete hybrid paradigm, and H infinity filtering is adopted as the estimation strategy. As H infinity filtering makes no assumptions on the system and measurement statistics, robust reconstruction results can be obtained for the dual-tracer PET imaging system where the statistical properties of measurement data and system uncertainty are not available a priori, even when there are disturbances in the kinetic parameters. Experimental results on digital phantoms, Monte Carlo simulations and physical phantoms have demonstrated the superior performance.
NASA Astrophysics Data System (ADS)
Pantelić, Dejan V.; Grujić, Dušan Ž.; Vasiljević, Darko M.
2014-12-01
We describe a method for dual-view biomechanical strain measurements of highly asymmetrical biological objects, like teeth or bones. By using a spherical mirror, we were able to simultaneously record a digital hologram of the object itself and the mirror image of its (otherwise invisible) rear side. A single laser beam was sufficient to illuminate both sides of the object, and to provide a reference beam. As a result, the system was mechanically very stable, enabling long exposure times (up to 2 min) without the need for vibration isolation. The setup is simple to construct and adjust, and can be used to interferometrically observe any object that is smaller than the mirror diameter. Parallel data processing on a CUDA-enabled (compute unified device architecture) graphics card was used to reconstruct digital holograms and to further correct image distortion. We used the setup to measure the deformation of a tooth due to mastication forces. The finite-element method was used to compare experimental results and theoretical predictions.
Pantelić, Dejan V; Grujić, Dušan Ž; Vasiljević, Darko M
2014-12-01
We describe a method for dual-view biomechanical strain measurements of highly asymmetrical biological objects, like teeth or bones. By using a spherical mirror, we were able to simultaneously record a digital hologram of the object itself and the mirror image of its (otherwise invisible) rear side. A single laser beam was sufficient to illuminate both sides of the object, and to provide a reference beam. As a result, the system was mechanically very stable, enabling long exposure times (up to 2 min) without the need for vibration isolation. The setup is simple to construct and adjust, and can be used to interferometrically observe any object that is smaller than the mirror diameter. Parallel data processing on a CUDA-enabled (compute unified device architecture) graphics card was used to reconstruct digital holograms and to further correct image distortion. We used the setup to measure the deformation of a tooth due to mastication forces. The finite-element method was used to compare experimental results and theoretical predictions.
Self-corrected chip-based dual-comb spectrometer.
Hébert, Nicolas Bourbeau; Genest, Jérôme; Deschênes, Jean-Daniel; Bergeron, Hugo; Chen, George Y; Khurmi, Champak; Lancaster, David G
2017-04-03
We present a dual-comb spectrometer based on two passively mode-locked waveguide lasers integrated in a single Er-doped ZBLAN chip. This original design yields two free-running frequency combs having a high level of mutual stability. We developed in parallel a self-correction algorithm that compensates residual relative fluctuations and yields mode-resolved spectra without the help of any reference laser or control system. Fluctuations are extracted directly from the interferograms using the concept of ambiguity function, which leads to a significant simplification of the instrument that will greatly ease its widespread adoption and commercial deployment. Comparison with a correction algorithm relying on a single-frequency laser indicates discrepancies of only 50 attoseconds on optical timings. The capacities of this instrument are finally demonstrated with the acquisition of a high-resolution molecular spectrum covering 20 nm. This new chip-based multi-laser platform is ideal for the development of high-repetition-rate, compact and fieldable comb spectrometers in the near- and mid-infrared.
A bilayer Double Semion Model with Symmetry-Enriched Topological Order
NASA Astrophysics Data System (ADS)
Ortiz, Laura; Martin-Delgado, Miguel Angel
We construct a new model of two-dimensional quantum spin systems that combines intrinsic topological orders and a global symmetry called flavour symmetry. It is referred as the bilayer Doubled Semion model (bDS) and is an instance of symmetry-enriched topological order. A honeycomb bilayer lattice is introduced to combine a Double Semion Topolgical Order with a global spin-flavour symmetry to get the fractionalization of its quasiparticles. The bDS model exhibits non-trival braiding self-statistics of excitations and its dual model constitutes a Symmetry-Protected Topological Order with novel edge states. This dual model gives rise to a bilayer Non-Trivial Paramagnet that is invariant under the flavour symmetry and the well-known spin flip symmetry. We acknowledge financial support from the Spanish MINECO Grants FIS2012-33152, FIS2015-67411, and the CAM research consortium QUITEMAD+, Grant No. S2013/ICE-2801. The research of M.A.M.-D. has been supported in part by the U.S. Army Research Office throu.
Jin, Hui; Gui, Rijun; Yu, Jianbo; Lv, Wei; Wang, Zonghua
2017-05-15
Previously developed electrochemical biosensors with single-electric signal output are probably affected by intrinsic and extrinsic factors. In contrast, the ratiometric electrochemical biosensors (RECBSs) with dual-electric signal outputs have an intrinsic built-in correction to the effects from system or background electric signals, and therefore exhibit a significant potential to improve the accuracy and sensitivity in electrochemical sensing applications. In this review, we systematically summarize the fabrication strategies, sensing modes and analytical applications of RECBSs. First, the different fabrication strategies of RECBSs were introduced, referring to the analytes-induced single- and dual-dependent electrochemical signal strategies for RECBSs. Second, the different sensing modes of RECBSs were illustrated, such as differential pulse voltammetry, square wave voltammetry, cyclic voltammetry, alternating current voltammetry, electrochemiluminescence, and so forth. Third, the analytical applications of RECBSs were discussed based on the types of target analytes. Finally, the forthcoming development and future prospects in the research field of RECBSs were also highlighted. Copyright © 2017 Elsevier B.V. All rights reserved.
Modelling and simulation of a thermally induced optical transparency in a dual micro-ring resonator
2017-01-01
This paper introduces the simulation and modelling of a novel dual micro-ring resonator. The geometric configuration of the resonators, and the implementation of a simulated broadband excitation source, results in the realization of optical transparencies in the combined through port output spectrum. The 130 nm silicon on insulator rib fabrication process is adopted for the simulation of the dual-ring configuration. Two titanium nitride heaters are positioned over the coupling regions of the resonators, which can be operated independently, to control the spectral position of the optical transparency. A third heater, centrally located above the dual resonator rings, can be used to red shift the entire spectrum to a required reference resonant wavelength. The free spectral range with no heater currents applied is 4.29 nm. For a simulated heater current of 7 mA (55.7 mW heater power) applied to one of the through coupling heaters, the optical transparency exhibits a red shift of 1.79 nm from the reference resonant wavelength. The ring-to-ring separation of approximately 900 nm means that it can be assumed that there is a zero ring-to-ring coupling field in this model. This novel arrangement has potential applications as a gas mass airflow sensor or a gas species identification sensor. PMID:28791167
Modelling and simulation of a thermally induced optical transparency in a dual micro-ring resonator.
Lydiate, Joseph
2017-07-01
This paper introduces the simulation and modelling of a novel dual micro-ring resonator. The geometric configuration of the resonators, and the implementation of a simulated broadband excitation source, results in the realization of optical transparencies in the combined through port output spectrum. The 130 nm silicon on insulator rib fabrication process is adopted for the simulation of the dual-ring configuration. Two titanium nitride heaters are positioned over the coupling regions of the resonators, which can be operated independently, to control the spectral position of the optical transparency. A third heater, centrally located above the dual resonator rings, can be used to red shift the entire spectrum to a required reference resonant wavelength. The free spectral range with no heater currents applied is 4.29 nm. For a simulated heater current of 7 mA (55.7 mW heater power) applied to one of the through coupling heaters, the optical transparency exhibits a red shift of 1.79 nm from the reference resonant wavelength. The ring-to-ring separation of approximately 900 nm means that it can be assumed that there is a zero ring-to-ring coupling field in this model. This novel arrangement has potential applications as a gas mass airflow sensor or a gas species identification sensor.
Pandolfo, Ignazio; Vinci, Sergio; Salamone, Ignazio; Granata, Francesca; Mazziotti, Silvio
2007-06-01
Our purpose is to codify the anterior ethmoidal artery (AEA) course and its relationship with adjacent structures. Twenty patients with cerebrovascular disease underwent selective internal carotid dual volume angiography. Fusion of the vascular and bony images was obtained successively on a second console. MDCT of the cranium was performed in all patients. To identify the AEA course, multiplanar CT reformations were obtained. In all cases the entry-point of AEA and its course were identified by means of dual volume angiography. The information was confirmed by MDCT. In a second phase, we studied another 78 patients affected by inflammatory disease and polyposis only by means of MDCT, in order to confirm the previous data obtained by comparison between angiography and MDCT. In this second phase, 110/156 vessels were indirectly detected by means of visualization of the ethmoidal entry point. In the remaining cases, AEA was directly shown due to integrity of the thin ethmoidal bone lamellae or bony canal. Dual volume angiography is essential to identify the course of the AEA (standard of reference for the interpretation of CT). In patients with benign rhinosinusal pathology, where invasivity techniques are not justified, MPR reconstructions were of pivotal importance in the evaluation of the course of the artery with particular reference to its relationship with the frontal recess.
Dual-energy digital mammography for calcification imaging: scatter and nonuniformity corrections.
Kappadath, S Cheenu; Shaw, Chris C
2005-11-01
Mammographic images of small calcifications, which are often the earliest signs of breast cancer, can be obscured by overlapping fibroglandular tissue. We have developed and implemented a dual-energy digital mammography (DEDM) technique for calcification imaging under full-field imaging conditions using a commercially available aSi:H/CsI:Tl flat-panel based digital mammography system. The low- and high-energy images were combined using a nonlinear mapping function to cancel the tissue structures and generate the dual-energy (DE) calcification images. The total entrance-skin exposure and mean-glandular dose from the low- and high-energy images were constrained so that they were similar to screening-examination levels. To evaluate the DE calcification image, we designed a phantom using calcium carbonate crystals to simulate calcifications of various sizes (212-425 microm) overlaid with breast-tissue-equivalent material 5 cm thick with a continuously varying glandular-tissue ratio from 0% to 100%. We report on the effects of scatter radiation and nonuniformity in x-ray intensity and detector response on the DE calcification images. The nonuniformity was corrected by normalizing the low- and high-energy images with full-field reference images. Correction of scatter in the low- and high-energy images significantly reduced the background signal in the DE calcification image. Under the current implementation of DEDM, utilizing the mammography system and dose level tested, calcifications in the 300-355 microm size range were clearly visible in DE calcification images. Calcification threshold sizes decreased to the 250-280 microm size range when the visibility criteria were lowered to barely visible. Calcifications smaller than approximately 250 microm were usually not visible in most cases. The visibility of calcifications with our DEDM imaging technique was limited by quantum noise, not system noise.
Dual-energy digital mammography for calcification imaging: Scatter and nonuniformity corrections
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kappadath, S. Cheenu; Shaw, Chris C.
Mammographic images of small calcifications, which are often the earliest signs of breast cancer, can be obscured by overlapping fibroglandular tissue. We have developed and implemented a dual-energy digital mammography (DEDM) technique for calcification imaging under full-field imaging conditions using a commercially available aSi:H/CsI:Tl flat-panel based digital mammography system. The low- and high-energy images were combined using a nonlinear mapping function to cancel the tissue structures and generate the dual-energy (DE) calcification images. The total entrance-skin exposure and mean-glandular dose from the low- and high-energy images were constrained so that they were similar to screening-examination levels. To evaluate the DEmore » calcification image, we designed a phantom using calcium carbonate crystals to simulate calcifications of various sizes (212-425 {mu}m) overlaid with breast-tissue-equivalent material 5 cm thick with a continuously varying glandular-tissue ratio from 0% to 100%. We report on the effects of scatter radiation and nonuniformity in x-ray intensity and detector response on the DE calcification images. The nonuniformity was corrected by normalizing the low- and high-energy images with full-field reference images. Correction of scatter in the low- and high-energy images significantly reduced the background signal in the DE calcification image. Under the current implementation of DEDM, utilizing the mammography system and dose level tested, calcifications in the 300-355 {mu}m size range were clearly visible in DE calcification images. Calcification threshold sizes decreased to the 250-280 {mu}m size range when the visibility criteria were lowered to barely visible. Calcifications smaller than {approx}250 {mu}m were usually not visible in most cases. The visibility of calcifications with our DEDM imaging technique was limited by quantum noise, not system noise.« less
Picometer-resolution dual-comb spectroscopy with a free-running fiber laser.
Zhao, Xin; Hu, Guoqing; Zhao, Bofeng; Li, Cui; Pan, Yingling; Liu, Ya; Yasui, Takeshi; Zheng, Zheng
2016-09-19
Dual-comb spectroscopy holds the promise as real-time, high-resolution spectroscopy tools. However, in its conventional schemes, the stringent requirement on the coherence between two lasers requires sophisticated control systems. By replacing control electronics with an all-optical dual-comb lasing scheme, a simplified dual-comb spectroscopy scheme is demonstrated using one dual-wavelength, passively mode-locked fiber laser. Pulses with a intracavity-dispersion-determined repetition-frequency difference are shown to have good mutual coherence and stability. Capability to resolve the comb teeth and a picometer-wide optical spectral resolution are demonstrated using a simple data acquisition system. Energy-efficient, free-running fiber lasers with a small comb-tooth-spacing could enable low-cost dual-comb systems.
Status of NGS CORS Network and Its Contribution to the GGOS Infrastructure
NASA Astrophysics Data System (ADS)
Choi, K. K.; Haw, D.; Sun, L.
2017-12-01
Recent advancement of Satellite Geodesy techniques can now contribute to the global frame realization needed to improve worldwide accuracies. These techniques rely on coordinates computed using continuously observed GPS data and corresponding satellite orbits. The GPS-based reference system continues to depend on the physical stability of a ground-based network of points as the primary foundation for these observations. NOAA's National Geodetic Survey (NGS) has been operating Continuously Operating Reference Stations (CORS) to provide direct access to the National Spatial Reference System (NSRS). By virtue of NGS' scientific reputation and leadership in national and international geospatial issues, NGS has determined to increase its participation in the maintenance of the U.S. component of the global GPS tracking network in order to realize a long-term stable national terrestrial reference frame. NGS can do so by leveraging its national leadership role coupled with NGS' scientific expertise, in designating and upgrading a subset of the current tracking network for this purpose. This subset of stations must have the highest operational standards to serve the dual functions: being the U.S. contribution to the international frame, along with providing the link to the national datum. These stations deserve special attention to ensure that the highest possible levels of quality and stability are maintained. To meet this need, NGS is working with the international scientific groups to add and designate these reference stations based on scientific merit such as: colocation with other geodetic techniques, geographic area, and monumentation stability.
NASA Astrophysics Data System (ADS)
Chen, Xilun; Wang, Xiangchuan; Pan, Shilong
2017-03-01
An implementation of a distance measurement system using double-sideband with suppressed carrier modulation (DSB-SC) frequency scanning interferometry is proposed to reduce the variations in the optical path and improve the measurement accuracy. In this proposed system, the electro-optic DSB-SC is used to create dual-swept signals with opposite scanning directions. For each swept signal, the relative distance between the reference arm and the measuring arm is determined by the beat frequency of signals from two arms. By multiplying both beat signals, measurement errors caused by variations in the optical path can be greatly reduced. As an experimental demonstration, a vibration was introduced in the optical path length. The experimental results show that the variations can be suppressed for over 19.9 dB.
Balhara, Yatan Pal Singh; Lev-Ran, Shaul; Martínez-Raga, José; Benyamina, Amine; Singh, Shalini; Blecha, Lisa; Szerman, Nestor
2016-01-01
This article overviews training, clinical services, and research on dual disorders across four countries: France, India, Israel, and Spain. The current dual disorders systems in each of the four countries were reviewed, with a focus on strengths and limitations of each. In France, psychiatric care occurs within the public health care system and involves little training of medical graduates for managing dual disorders. Special courses and forums for specialists have recently started to meet the growing interest of physicians in learning how to manage dual disorders. The Indian health care system grapples with a large treatment gap for mental disorders, and while some treatment services for dual disorders exist, specific research and training efforts on dual disorders are just beginning. Israel has both public- and private sector services for patients with dual disorders, with specialized inpatient and emergency care for the acutely ill as well as day care and therapeutic communities for long-term management. Interest by researchers is growing, but training and education efforts in dual disorders are, however, minimal. Similar to the other countries, addiction and psychiatry disciplines are governed by separate divisions within the National Health System in Spain. There are some dual disorders services available, but they are limited in scope. While medical professionals clearly recognize the importance of dual disorders, there is no such recognition by the national and regional governing bodies. The common thread in various aspects of dual disorder management in each of these four countries is that there is a lower-than-desirable level of attention to dual disorders in terms of care, policy, research, and training. There are growing opportunities for training and continuing education in dual disorders management. We suggest that nations could learn from each other's experiences on how to address the issue of dual disorders.
Kinnunen, Suna Pirita; Windmann, Sabine
2013-01-01
Altruism refers to an other-benefiting behavior that is costly but bears no direct profit to oneself. At least three different forms can be distinguished: help giving, altruistic punishment, and moral courage. We investigated the differential impact of two thinking modes, intuitive (System 1) and rational (System 2), on these three altruistic behaviors. Situational (state-related) thinking style was manipulated via experimental instructions and generally preferred thinking style (trait-related) was assessed via questionnaires. We found that of the subjectively preferred thinking styles (trait), faith in intuition (System 1) promoted sharing and altruistic punishment, whereas need for cognition (System 2) promoted volunteering in a situation that required moral courage. By contrast, we did not find a significant effect of situational thinking style (state) on any of the altruistic behaviors, although manipulation checks were positive. Results elucidate the affective-motivational underpinnings of different types of altruistic behaviors. PMID:23616778
Dual Logic and Cerebral Coordinates for Reciprocal Interaction in Eye Contact
Lee, Ray F.
2015-01-01
In order to scientifically study the human brain’s response to face-to-face social interaction, the scientific method itself needs to be reconsidered so that both quantitative observation and symbolic reasoning can be adapted to the situation where the observer is also observed. In light of the recent development of dyadic fMRI which can directly observe dyadic brain interacting in one MRI scanner, this paper aims to establish a new form of logic, dual logic, which provides a theoretical platform for deductive reasoning in a complementary dual system with emergence mechanism. Applying the dual logic in the dfMRI experimental design and data analysis, the exogenous and endogenous dual systems in the BOLD responses can be identified; the non-reciprocal responses in the dual system can be suppressed; a cerebral coordinate for reciprocal interaction can be generated. Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system. Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature. Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction. PMID:25885446
Costs and energy efficiency of a dual-mode system
NASA Technical Reports Server (NTRS)
Heft, R. C.
1977-01-01
The life cycle costs of a dual mode system for both public and semiprivate ownership are examined, and the costs in terms of levelized required revenue per passenger mile are presented. The energy use of the dual mode vehicle is analyzed by means of a detailed vehicle simulation program for the control policy and guideway system. Several different propulsion systems are considered.
The Dual System of Vocational Training in Germany. BASIS-INFO 11-1995. Social Policy.
ERIC Educational Resources Information Center
Kraemer, Dagmar
The dual system of vocational training is a joint government-industry program and part of the general educational system in Germany. It provides hands-on training in private businesses coupled with specialized instruction in public vocational schools at no cost to students. The objective of the dual system is to provide young people with the best…
Dual-systems and the development of reasoning: competence-procedural systems.
Overton, Willis F; Ricco, Robert B
2011-03-01
Dual-system, dual-process, accounts of adult cognitive processing are examined in the context of a self-organizing relational developmental systems approaches to cognitive growth. Contemporary adult dual-process accounts describe a linear architecture of mind entailing two split-off, but interacting systems; a domain general, content-free 'analytic' system (system 2) and a domain specific highly contextualized 'heuristic' system (system 1). In the developmental literature on deductive reasoning, a similar distinction has been made between a domain general competence (reflective, algorithmic) system and a domain specific procedural system. In contrast to the linear accounts offered by empiricist, nativist, and/or evolutionary explanations, the dual competence-procedural developmental perspective argues that the mature systems emerge through developmental transformations as differentiations and intercoordinations of an early relatively undifferentiated action matrix. This development, whose microscopic mechanism is action-in-the-world, is characterized as being embodied, nonlinear, and epigenetic. WIREs Cogni Sci 2011 2 231-237 DOI: 10.1002/wcs.120 For further resources related to this article, please visit the WIREs website. © 2010 John Wiley & Sons, Ltd.
Sen. Lugar, Richard G. [R-IN
2011-01-25
Senate - 01/25/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Dual-band plasmonic resonator based on Jerusalem cross-shaped nanoapertures
NASA Astrophysics Data System (ADS)
Cetin, Arif E.; Kaya, Sabri; Mertiri, Alket; Aslan, Ekin; Erramilli, Shyamsunder; Altug, Hatice; Turkmen, Mustafa
2015-06-01
In this paper, we both experimentally and numerically introduce a dual-resonant metamaterial based on subwavelength Jerusalem cross-shaped apertures. We numerically investigate the physical origin of the dual-resonant behavior, originating from the constituting aperture elements, through finite difference time domain calculations. Our numerical calculations show that at the dual-resonances, the aperture system supports large and easily accessible local electromagnetic fields. In order to experimentally realize the aperture system, we utilize a high-precision and lift-off free fabrication method based on electron-beam lithography. We also introduce a fine-tuning mechanism for controlling the dual-resonant spectral response through geometrical device parameters. Finally, we show the aperture system's highly advantageous far- and near-field characteristics through numerical calculations on refractive index sensitivity. The quantitative analyses on the availability of the local fields supported by the aperture system are employed to explain the grounds behind the sensitivity of each spectral feature within the dual-resonant behavior. Possessing dual-resonances with large and accessible electromagnetic fields, Jerusalem cross-shaped apertures can be highly advantageous for wide range of applications demanding multiple spectral features with strong nearfield characteristics.
Hybrid Nanoparticles for Detection and Treatment of Cancer
Sailor, Michael J.; Park, Ji-Ho
2012-01-01
There is currently considerable effort to incorporate both diagnostic and therapeutic functions into a single nanoscale system for the more effective treatment of cancer. Nanoparticles have great potential to achieve such dual functions, particularly if more than one type of nanostructure can be incorporated in a nanoassembly—referred to in this review as a hybrid nanoparticle. Here we review recent developments in the synthesis and evaluation of such hybrid nanoparticles based on two design strategies (barge vs. tanker), in which liposomal, micellar, porous silica, polymeric, viral, noble metal, and nanotube systems are incorporated either within (barge) or at the surface of (tanker) a nanoparticle. We highlight the design factors that should be considered to obtain effective nanodevices for cancer detection and treatment. PMID:22610698
NASA Technical Reports Server (NTRS)
Liu, H. K.
1978-01-01
A phase modulated triple exposure technique was incorporated into a holographic nondestructive test (HNDT) system. The technique was able to achieve a goal of simultaneously identifying the zero-order fringe and determining the direction of motion (or displacement). Basically, the technique involves the addition of one more exposure, during the loading of the tested object, to the conventional double-exposure hologram. A phase shifter is added to either the object beam or the reference beam during the second and third exposure. Theoretical analysis with the assistance of computer simulation illustrated the feasibility of implementing the phase modulation and triple-exposure in the HNDT systems. Main advantages of the technique are the enhancement of accuracy in data interpretation and a better determination of the nature of the flaws in the tested object.
NASA Astrophysics Data System (ADS)
Curry, Nicholas; Markocsan, Nicolaie; Östergren, Lars; Li, Xin-Hai; Dorfman, Mitch
2013-08-01
The aim of this study was the further development of dysprosia-stabilized zirconia coatings for gas turbine applications. The target for these coatings was a longer lifetime and higher insulating performance compared to today's industrial standard thermal barrier coating. Two morphologies of ceramic top coat were studied: one using a dual-layer system and the second using a polymer to generate porosity. Evaluations were carried out using a laser flash technique to measure thermal properties. Lifetime testing was conducted using thermo-cyclic fatigue testing. Microstructure was assessed with SEM and Image analysis was used to characterize porosity content. The results show that coatings with an engineered microstructure give performance twice that of the present reference coating.
Supporting College Success Through Dual Enrollment Act
Sen. Sanders, Bernard [I-VT
2014-05-15
Senate - 05/15/2014 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Inoue, Takashi; Namiki, Shu
2013-12-02
We find that an adaptive equalizer and a phase-locked loop operating with decision-directed mode exhibit degraded performances when they are used in a digital coherent receiver to demodulate a 16QAM signal with intrinsically distorted constellation, and that the degradation is more significant for the dual-polarization case. We then propose a scheme to correctly demodulate such a distorted 16QAM signal, where the reference constellation and the threshold for the decision are adaptively adjusted such that they fit to the distorted ones. We experimentally confirm the improved performance of the proposed scheme over the conventional one for single-and dual-polarization 16QAM signals with distortion. We also investigate the applicable range of the proposed scheme for the degree of distortion of the signal.
Ionospheric error contribution to GNSS single-frequency navigation at the 2014 solar maximum
NASA Astrophysics Data System (ADS)
Orus Perez, Raul
2017-04-01
For single-frequency users of the global satellite navigation system (GNSS), one of the main error contributors is the ionospheric delay, which impacts the received signals. As is well-known, GPS and Galileo transmit global models to correct the ionospheric delay, while the international GNSS service (IGS) computes precise post-process global ionospheric maps (GIM) that are considered reference ionospheres. Moreover, accurate ionospheric maps have been recently introduced, which allow for the fast convergence of the real-time precise point position (PPP) globally. Therefore, testing of the ionospheric models is a key issue for code-based single-frequency users, which constitute the main user segment. Therefore, the testing proposed in this paper is straightforward and uses the PPP modeling applied to single- and dual-frequency code observations worldwide for 2014. The usage of PPP modeling allows us to quantify—for dual-frequency users—the degradation of the navigation solutions caused by noise and multipath with respect to the different ionospheric modeling solutions, and allows us, in turn, to obtain an independent assessment of the ionospheric models. Compared to the dual-frequency solutions, the GPS and Galileo ionospheric models present worse global performance, with horizontal root mean square (RMS) differences of 1.04 and 0.49 m and vertical RMS differences of 0.83 and 0.40 m, respectively. While very precise global ionospheric models can improve the dual-frequency solution globally, resulting in a horizontal RMS difference of 0.60 m and a vertical RMS difference of 0.74 m, they exhibit a strong dependence on the geographical location and ionospheric activity.
Evaluation of a New 1H/31P Dual-Tuned Birdcage Coil for 31P Spectroscopy
Potter, WM; Wang, L; McCully, KK; Zhao, Q
2013-01-01
We introduce a new dual-tuned Hydrogen/Phosphorus (1H/31P) birdcage coil, referred to as split birdcage coil, and evaluate its performance using both simulations and magnetic resonance (MR) experiments on a 3 T MR scanner. The proposed coil simplifies the practical matters of tuning and matching, which makes the coil easily reproducible. Simulations were run with the Finite Difference in Time Domain (FDTD) method to evaluate the sensitivity and homogeneity of the magnetic field generated by the proposed 1H coils. Following simulations, MR experiments were conducted using both a phantom and human thigh to compare the proposed design with a currently available commercial dual-tuned flexible surface coil, referred to as flex surface coil, for signal to noise ratio (SNR) as well as homogeneity for the 31P coil. At regions deep within the human thigh, the split birdcage coil was able to acquire spectroscopic signal with a higher average SNR than the flex surface coil. For all regions except those close to the flex surface coil, the split birdcage coil matched or exceeded the performance of the flex surface coil. PMID:24039555
NASA Astrophysics Data System (ADS)
Zou, X.; Deng, Z.; Ge, M.; Dick, G.; Jiang, W.; Liu, J.
2010-07-01
In order to obtain crustal deformations of higher spatial resolution, existing GPS networks must be densified. This densification can be carried out using single-frequency receivers at moderate costs. However, ionospheric delay handling is required in the data processing. We adapt the Satellite-specific Epoch-differenced Ionospheric Delay model (SEID) for GPS networks with mixed single- and dual-frequency receivers. The SEID model is modified to utilize the observations from the three nearest dual-frequency reference stations in order to avoid contaminations from more remote stations. As data of only three stations are used, an efficient missing data constructing approach with polynomial fitting is implemented to minimize data losses. Data from large scale reference networks extended with single-frequency receivers can now be processed, based on the adapted SEID model. A new data processing scheme is developed in order to make use of existing GPS data processing software packages without any modifications. This processing scheme is evaluated using a sub-network of the German SAPOS network. The results verify that the new scheme provides an efficient way to densify existing GPS networks with single-frequency receivers.
A Dual System Model of Preferences under Risk
ERIC Educational Resources Information Center
Mukherjee, Kanchan
2010-01-01
This article presents a dual system model (DSM) of decision making under risk and uncertainty according to which the value of a gamble is a combination of the values assigned to it independently by the affective and deliberative systems. On the basis of research on dual process theories and empirical research in Hsee and Rottenstreich (2004) and…
The German 'Dual System' of Occupational Training: A Much-Replicated but Oft-Failed Transfer.
ERIC Educational Resources Information Center
Wilson, David N.
Germany's Dual System, which consists of in-school and in-enterprise components, facilitates entry into 374 recognized technical, white-collar and blue-collar occupations listed in training regulations that are grounded in legislation. The Dual System's origins and development in Germany were examined along with several attempts to replicate the…
Dual Vector Spaces and Physical Singularities
NASA Astrophysics Data System (ADS)
Rowlands, Peter
Though we often refer to 3-D vector space as constructed from points, there is no mechanism from within its definition for doing this. In particular, space, on its own, cannot accommodate the singularities that we call fundamental particles. This requires a commutative combination of space as we know it with another 3-D vector space, which is dual to the first (in a physical sense). The combination of the two spaces generates a nilpotent quantum mechanics/quantum field theory, which incorporates exact supersymmetry and ultimately removes the anomalies due to self-interaction. Among the many natural consequences of the dual space formalism are half-integral spin for fermions, zitterbewegung, Berry phase and a zero norm Berwald-Moor metric for fermionic states.
NASA Astrophysics Data System (ADS)
Yang, Ruitao; Pollinger, Florian; Meiners-Hagen, Karl; Krystek, Michael; Tan, Jiubin; Bosse, Harald
2015-08-01
We present a dual-comb-based heterodyne multi-wavelength absolute interferometer capable of long distance measurements. The phase information of the various comb modes is extracted in parallel by a multi-channel digital lock-in phase detection scheme. Several synthetic wavelengths of the same order are constructed and the corresponding phases are averaged to deduce the absolute lengths with significantly reduced uncertainty. Comparison experiments with an incremental HeNe reference interferometer show a combined relative measurement uncertainty of 5.3 × 10-7 at a measurement distance of 20 m. Combining the advantage of synthetic wavelength interferometry and dual-comb interferometry, our compact and simple approach provides sufficient precision for many industrial applications.
Longitudinal effects of bilingualism on dual-tasking
Josefsson, Maria; Marsh, John E.; Hansson, Patrik; Ljungberg, Jessica K.
2017-01-01
An ongoing debate surrounds whether bilinguals outperform monolinguals in tests of executive processing. The aim of this study was to investigate if there are long-term (10 year) bilingual advantages in executive processing, as indexed by dual-task performance, in a sample that were 40–65 years at baseline. The bilingual (n = 24) and monolingual (n = 24) participants were matched on age, sex, education, fluid intelligence, and study sample. Participants performed free-recall for a 12-item list in three dual-task settings wherein they sorted cards either during encoding, retrieval, or during both encoding and retrieval of the word-list. Free recall without card sorting was used as a reference to compute dual-task costs. The results showed that bilinguals significantly outperformed monolinguals when they performed card-sorting during both encoding and retrieval of the word-list, the condition that presumably placed the highest demands on executive functioning. However, dual-task costs increased over time for bilinguals relative to monolinguals, a finding that is possibly influenced by retirement age and limited use of second language in the bilingual group. PMID:29281654
Technology, Applications, and Process Challenges of Dual Chamber Systems.
Werk, Tobias; Ludwig, Imke S; Luemkemann, Joerg; Mahler, Hanns-Christian; Huwyler, Joerg; Hafner, Mathias
2016-01-01
Dual-chamber systems provide an option as a drug and device combination product, when home care and emergency lyophilized products are intended. Nevertheless, until today, there are only a few products on the market, due to the challenges and limitations in manufacturability, product formulation, and product stability in a dual-chamber configuration, as well as economic considerations. This review serves to describe currently available dual-chamber systems and to discuss factors to be considered for appropriate selection and establishing fill-finish processes. Copyright © 2016. Published by Elsevier Inc.
NASA Astrophysics Data System (ADS)
Hara, Toshitsugu
Elementary education program for engineering by the dual system combined with workshop program and teaching program with practical subject was discussed. The dual system which consists of several workshop programs and fundamental subjects (such as mathematics, English and physics) with practical material has been performed for the freshmen. The elementary workshop program (primary course) has four workshops and the related lectures. Fundamental subjects are taught with the practical or engineering texts. English subjects are taught by specified teachers who have ever worked in engineering field with English. The dual system was supported by such systems as the center for success initiative and the English education center.
NASA Astrophysics Data System (ADS)
Deng, Shi-ting; Yu, Hong; Liu, Di; Bi, Yong-guang
2017-10-01
To investigate how a dual- or single-frequency ultrasonic reactor changes the morphology and phase composition of hydroxyapatite nanoparticles (nHAPs), we designed and constructed the preparation of nHAPs using dual- or single-frequency ultrasonic devices, i.e., the single frequency ultrasonic generator with ultrasonic horn (25 kHz), the ultrasonic bath (40 kHz) and the dual-frequency sonochemical systems combined with the ultrasonic horn and the ultrasonic bath simultaneously (25 + 40 kHz). The results showed that the sonicated samples displayed a more uniform shape with less agglomeration than non-sonicated sample. The rod-shaped particles with 1.66 stoichiometry and without a second phase were synthesized successfully in the ultrasonic bath or horn systems. The nHAPs obtained from the dual-frequency ultrasonic systems exhibited a regular rod-shaped structure with better dispersion and more uniform shapes than those of obtained in either ultrasonic bath or horn systems. Additionally, the size of rod-shaped particles obtained in the dual-frequency ultrasound with a mean width of 35 nm and a mean length of 64 nm was smaller than other samples. A possible mechanism is that the dual-frequency ultrasound significantly enhances the cavitation yield over single frequency ultrasound and thus improves the dispersion of particles and reduces the size of the crystals. In addition, irregular holes can be observed in the nanoparticles obtained in the dual-frequency ultrasound. Therefore, the dual-frequency ultrasonic systems are expected to become a convenient, efficient and environmentally friendly synthetic technology to obtain well-defined nHAPs for specific biomedical applications.
Design of a dual-mode electrochemical measurement and analysis system.
Yang, Jr-Fu; Wei, Chia-Ling; Wu, Jian-Fu; Liu, Bin-Da
2013-01-01
A dual-mode electrochemical measurement and analysis system is proposed. This system includes a dual-mode chip, which was designed and fabricated by using TSMC 0.35 µm 3.3 V/5 V 2P4M mixed-signal CMOS process. Two electrochemical measurement and analysis methods, chronopotentiometry and voltammetry, can be performed by using the proposed chip and system. The proposed chip and system are verified successfully by performing voltammetry and chronopotentiometry on solutions.
New Processes for Freeze-Drying in Dual-Chamber Systems.
Werk, T; Ludwig, I S; Luemkemann, J; Huwyler, J; Mahler, H-C; Haeuser, C R; Hafner, M
2016-01-01
Dual-chamber systems can offer self-administration and home care use for lyophilized biologics. Only a few products have been launched in dual-chamber systems so far-presumably due to dual-chamber systems' complex and costly drug product manufacturing process. Within this paper, two improved processes (both based on tray filling technology) for freeze-drying pharmaceuticals in dual-chamber systems are described. Challenges with regards to heat transfer were tackled by (1) performing the freeze-drying step in a needle-down orientation in combination with an aluminum block, or (2) freeze-drying the drug product "externally" in a metal cartridge with subsequent filling of the lyophilized cake into the dual-chamber system. Metal-mediated heat transfer was shown to be efficient in both cases and batch (unit-to-unit) homogeneity with regards to sublimation rate was increased. It was difficult to influence ice crystal size using different methods when in use with an aluminum block due to its heat capacity. Using such a metal carrier implies a large heat capacity leading to relatively small ice crystals. Compared to the established process, drying times were reduced by half using the new processes. The drying time was, however, longer for syringes compared to vials due to the syringe design (long and slim). The differences in drying times were less pronounced for aggressive drying cycles. The proposed processes may help to considerably decrease investment costs into dual-chamber system fill-finish equipment. Dual-chamber syringes offer self-administration and home care use for freeze-dried pharmaceuticals. Only a few products have been launched in dual-chamber syringes so far-presumably due to their complex and costly drug product manufacturing process. In this paper two improved processes for freeze-drying pharmaceuticals in dual-chamber syringes are described. The major challenge of freeze-drying is to transfer heat through a vacuum. The proposed processes cope with this challenge by (1) freeze-drying the drug product in the syringe in an orientation in which the product is closest to the heat source, or (2) freeze-drying the drug product outside the syringe in a metal tube. The latter requires filling the freeze-dried product subsequently into the dual-chamber syringe. Both processes were very efficient and promised to achieve similar freeze-drying conditions for all dual-chamber syringes within one production run. The proposed processes may help to considerably decrease investment costs into dual-chamber syringe fill-finish equipment. © PDA, Inc. 2016.
Flight code validation simulator
NASA Astrophysics Data System (ADS)
Sims, Brent A.
1996-05-01
An End-To-End Simulation capability for software development and validation of missile flight software on the actual embedded computer has been developed utilizing a 486 PC, i860 DSP coprocessor, embedded flight computer and custom dual port memory interface hardware. This system allows real-time interrupt driven embedded flight software development and checkout. The flight software runs in a Sandia Digital Airborne Computer and reads and writes actual hardware sensor locations in which Inertial Measurement Unit data resides. The simulator provides six degree of freedom real-time dynamic simulation, accurate real-time discrete sensor data and acts on commands and discretes from the flight computer. This system was utilized in the development and validation of the successful premier flight of the Digital Miniature Attitude Reference System in January of 1995 at the White Sands Missile Range on a two stage attitude controlled sounding rocket.
Photovoltaic Inverter Controllers Seeking AC Optimal Power Flow Solutions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dall'Anese, Emiliano; Dhople, Sairaj V.; Giannakis, Georgios B.
This paper considers future distribution networks featuring inverter-interfaced photovoltaic (PV) systems, and addresses the synthesis of feedback controllers that seek real- and reactive-power inverter setpoints corresponding to AC optimal power flow (OPF) solutions. The objective is to bridge the temporal gap between long-term system optimization and real-time inverter control, and enable seamless PV-owner participation without compromising system efficiency and stability. The design of the controllers is grounded on a dual ..epsilon..-subgradient method, while semidefinite programming relaxations are advocated to bypass the non-convexity of AC OPF formulations. Global convergence of inverter output powers is analytically established for diminishing stepsize rules formore » cases where: i) computational limits dictate asynchronous updates of the controller signals, and ii) inverter reference inputs may be updated at a faster rate than the power-output settling time.« less
Achievable flatness in a large microwave power transmitting antenna
NASA Technical Reports Server (NTRS)
Ried, R. C.
1980-01-01
A dual reference SPS system with pseudoisotropic graphite composite as a representative dimensionally stable composite was studied. The loads, accelerations, thermal environments, temperatures and distortions were calculated for a variety of operational SPS conditions along with statistical considerations of material properties, manufacturing tolerances, measurement accuracy and the resulting loss of sight (LOS) and local slope distributions. A LOS error and a subarray rms slope error of two arc minutes can be achieved with a passive system. Results show that existing materials measurement, manufacturing, assembly and alignment techniques can be used to build the microwave power transmission system antenna structure. Manufacturing tolerance can be critical to rms slope error. The slope error budget can be met with a passive system. Structural joints without free play are essential in the assembly of the large truss structure. Variations in material properties, particularly for coefficient of thermal expansion from part to part, is more significant than actual value.
Performance evaluation of a LYSO-based PET scanner for monitoring of dose delivery in hadrontherapy
NASA Astrophysics Data System (ADS)
Fabbiani, E.; Belcari, N.; Camarlinghi, N.; Del Guerra, A.; Ferretti, S.; Kraan, A.; Panetta, D.; Sportelli, G.; Rosso, V.
2015-12-01
The DoPET scanner is a compact positron emission tomography (PET) device. It has been developed for monitoring the range of charged particles during therapy with hadron beams. Previous works have focused on the development and upgrade of the device and on data analysis. In this paper, a full performance characterization of the DoPET system in terms of the energy resolution, spatial resolution, sensitivity, uniformity, and noise equivalent count rate is reported. All measurements refer to an adapted version of the National Electrical Manufacturers Association (NEMA) NU 4 - 2008 protocol, which was written originally for small animal PET systems. Since DoPET is a dual head planar system, it requires a modified characterisation procedure with respect to those described for ring geometries as in the NEMA NU 4 - 2008 protocol. The presented procedure may be of interest for any other PET system with a similar geometry as DoPET.
Econometric comparisons of liquid rocket engines for dual-fuel advanced earth-to-orbit shuttles
NASA Technical Reports Server (NTRS)
Martin, J. A.
1978-01-01
Econometric analyses of advanced Earth-to-orbit vehicles indicate that there are economic benefits from development of new vehicles beyond the space shuttle as traffic increases. Vehicle studies indicate the advantage of the dual-fuel propulsion in single-stage vehicles. This paper shows the economic effect of incorporating dual-fuel propulsion in advanced vehicles. Several dual-fuel propulsion systems are compared to a baseline hydrogen and oxygen system.
Terrier, Alexandre; Latypova, Adeliya; Guillemin, Maika; Parvex, Valérie; Guyen, Olivier
2017-03-01
Constrained devices, standard implants with large heads, and dual mobility systems have become popular options to manage instability after total hip arthroplasty (THA). Clinical results with these options have shown variable success rates and significant higher rates of aseptic loosening and mechanical failures with constrained implants. Literature suggests potential advantages of dual mobility, however little is known about its biomechanics. We present a comparative biomechanical study of a standard implant, a constrained implant, and a dual mobility system. A finite element analysis was developed to assess and compare these acetabular options with regard to the range of motion (ROM) to impingement, the angle of dislocation, the resistive torque, the volume of polyethylene (PE) with a stress above 80% of the elastic limit, and the interfacial cup/bone stress. Dual mobility implants provided the greatest ROM to impingement and allowed delaying subluxation and dislocation when compared to standard and constrained implants. Dual mobility also demonstrated the lowest resistive torque at subluxation while the constrained implant provided the greatest one. The lowest critical PE volume was observed with the dual mobility implant, and the highest stress at the interfaces was observed with the constrained implant. This study highlights the biomechanical advantages of dual mobility systems over constrained and standard implants, and is supported by the clinical results reported. Therefore, the use of dual mobility systems in situations at risk for instability should be advocated and constrained implants should be restricted to salvage situations.
NASA Astrophysics Data System (ADS)
Nishino, Hitoshi; Rajpoot, Subhash
2018-03-01
We formulate an N = (2 , 0) system in D = 3 + 3 dimensions consisting of a Yang-Mills (YM)-multiplet (ˆ μ ˆ IA, λˆI), a self-dual non-Abelian tensor multiplet (ˆ μ ˆ ν ˆ IB, χˆI ,φˆI), and an extra vector multiplet (C ˆ μ ˆ IC, ρˆI). We next perform the dimensional reductions of this system into D = 2 + 2, and obtain N = (1 , 1) systems with a self-dual YM-multiplet (AIμ ,λI), a self-dual tensor multiplet (BIμν , χI , φI), and an extra vector multiplet (CIμ , ρI). In D = 2 + 2, we reach two distinct theories: 'Theory-I' and 'Theory-II'. The former has the self-dual field-strength Hμν(+)I of CIμ already presented in our recent paper, while the latter has anti-self-dual field strength Hμν(-)I. As an application, we show that Theory-II actually generates supersymmetric-KdV equations in D = 1 + 1. Our result leads to a new conclusion that the D = 3 + 3 theory with non-Abelian tensor multiplet can be a 'Grand Master Theory' for self-dual multiplet and self-dual YM-multiplet in D = 2 + 2, that in turn has been conjectured to be the 'Master Theory' for all supersymmetric integrable theories in D ≤ 3.
46 CFR 120.324 - Dual voltage generators.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Dual voltage generators. 120.324 Section 120.324... INSTALLATION Power Sources and Distribution Systems § 120.324 Dual voltage generators. (a) A dual voltage generator installed on a vessel shall be of the grounded type, where: (1) The neutral of a dual voltage...
Pitfalls in the measurement of muscle mass: a need for a reference standard
Landi, Francesco; Cesari, Matteo; Fielding, Roger A.; Visser, Marjolein; Engelke, Klaus; Maggi, Stefania; Dennison, Elaine; Al‐Daghri, Nasser M.; Allepaerts, Sophie; Bauer, Jurgen; Bautmans, Ivan; Brandi, Maria Luisa; Bruyère, Olivier; Cederholm, Tommy; Cerreta, Francesca; Cherubini, Antonio; Cooper, Cyrus; Cruz‐Jentoft, Alphonso; McCloskey, Eugene; Dawson‐Hughes, Bess; Kaufman, Jean‐Marc; Laslop, Andrea; Petermans, Jean; Reginster, Jean‐Yves; Rizzoli, René; Robinson, Sian; Rolland, Yves; Rueda, Ricardo; Vellas, Bruno; Kanis, John A.
2018-01-01
Abstract Background All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the best technique for measuring lean body mass. Thus, the objective measurement of sarcopenia is hampered by limitations intrinsic to assessment tools. The aim of this study was to review the methods to assess muscle mass and to reach consensus on the development of a reference standard. Methods Literature reviews were performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis working group on frailty and sarcopenia. Face‐to‐face meetings were organized for the whole group to make amendments and discuss further recommendations. Results A wide range of techniques can be used to assess muscle mass. Cost, availability, and ease of use can determine whether the techniques are better suited to clinical practice or are more useful for research. No one technique subserves all requirements but dual energy X‐ray absorptiometry could be considered as a reference standard (but not a gold standard) for measuring muscle lean body mass. Conclusions Based on the feasibility, accuracy, safety, and low cost, dual energy X‐ray absorptiometry can be considered as the reference standard for measuring muscle mass. PMID:29349935
A dynamic dual process model of risky decision making.
Diederich, Adele; Trueblood, Jennifer S
2018-03-01
Many phenomena in judgment and decision making are often attributed to the interaction of 2 systems of reasoning. Although these so-called dual process theories can explain many types of behavior, they are rarely formalized as mathematical or computational models. Rather, dual process models are typically verbal theories, which are difficult to conclusively evaluate or test. In the cases in which formal (i.e., mathematical) dual process models have been proposed, they have not been quantitatively fit to experimental data and are often silent when it comes to the timing of the 2 systems. In the current article, we present a dynamic dual process model framework of risky decision making that provides an account of the timing and interaction of the 2 systems and can explain both choice and response-time data. We outline several predictions of the model, including how changes in the timing of the 2 systems as well as time pressure can influence behavior. The framework also allows us to explore different assumptions about how preferences are constructed by the 2 systems as well as the dynamic interaction of the 2 systems. In particular, we examine 3 different possible functional forms of the 2 systems and 2 possible ways the systems can interact (simultaneously or serially). We compare these dual process models with 2 single process models using risky decision making data from Guo, Trueblood, and Diederich (2017). Using this data, we find that 1 of the dual process models significantly outperforms the other models in accounting for both choices and response times. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
NASA Astrophysics Data System (ADS)
Geng, Ying; Li, Shenping; Li, Ming-Jun; Sutton, Clifford G.; McCollum, Robert L.; McClure, Randy L.; Koklyushkin, Alexander V.; Matthews, Karen I.; Luther, James P.; Butler, Douglas L.
2015-03-01
A complete single mode dual-core fiber system for short-reach optical interconnects is fabricated and tested for high-speed data transmission. It includes dual-core fibers capable of bi-directional data transmission, dual-core simplex LC connectors, and fan-outs. The transmission system offers simplified bi-directional traffic engineering with integrated bidirectional transceivers and compact system design, utilizing simplex dual-core LC connectors that use half the space while increasing the bandwidth density by a factor of two. The fiber has two cores that are compatible with single mode fiber and conforms to the industry standard outer diameter of 125 μm. This reduces operational complexity by reducing the size and number of fibers, cables and connectors. Measured OTDR loss for both cores was 0.34 dB/km at 1310 nm and 0.19 dB/km at 1550 nm. Crosstalk for a piece of 5.8 km long dual-core fiber was measured to be below -75 dB at 1310 nm, and below -40 dB at 1550 nm. Both free-space optics fan-outs and tapered-fiber-coupler based MCF fan-outs were evaluated for the transmission system. Error-free and penalty-free 25 Gb/s bi-directional transmission performance was demonstrated for three different fiber lengths, 200 m, 2 km and 10 km, using the complete all-fiber-based system including connectors and fan-outs. This single mode, dual-core fiber transmission system adds complementary value to systems where additional increases in bandwidth density can come from wavelength division multiplexing and multiple bits per symbol.
Dual education and industrial cooperation in electrical engineering
NASA Astrophysics Data System (ADS)
Váradiné Szarka, A.
2016-11-01
Dual education in higher education is a new system in Hungary introduced by Mercedes Benz with cooperation of Kecskemet College. In the new system companies support certain number of students and provide them strong practical education in their field. Students applying successfully for dual education study together with non-dual students at the university, so they go through the same university courses as their non-dual colleagues, but while non-dual students’ academic year includes 2×14 weeks active semester and 2×6 weeks exam session, all over 40 weeks, dual students have 48 working weeks including study at the university and practicing at the company. The main question of the success which one is the most effective model to be applied. This paper summarises 2 models of dual education with their advantages and disadvantages and also it presents practical realization at the University of Debrecen with special attention to measurement and instrumentation. Dual education in BSc level electrical engineering course cooperates with 6 multinational companies of the region in four specialization. Dual education also has great impact to the modernisation of engineering education. Detailed study of dual education in field of instrumentation and measurement is provided in the paper.
40 CFR 270.25 - Specific part B information requirements for equipment.
Code of Federal Regulations, 2011 CFR
2011-07-01
... detection and repair” or “equipped with dual mechanical seals”). (b) For facilities that cannot install a... by reference as specified in § 270.6) or other engineering texts acceptable to the Regional...
NASA Astrophysics Data System (ADS)
Liu, Shuangquan; Zhang, Bin; Wang, Xin; Li, Lin; Chen, Yan; Liu, Xin; Liu, Fei; Shan, Baoci; Bai, Jing
2011-02-01
A dual-modality imaging system for simultaneous fluorescence molecular tomography (FMT) and positron emission tomography (PET) of small animals has been developed. The system consists of a noncontact 360°-projection FMT module and a flat panel detector pair based PET module, which are mounted orthogonally for the sake of eliminating cross interference. The FMT images and PET data are simultaneously acquired by employing dynamic sampling mode. Phantom experiments, in which the localization and range of radioactive and fluorescence probes are exactly indicated, have been carried out to verify the feasibility of the system. An experimental tumor-bearing mouse is also scanned using the dual-modality simultaneous imaging system, the preliminary fluorescence tomographic images and PET images demonstrate the in vivo performance of the presented dual-modality system.
NASA Astrophysics Data System (ADS)
Kartashov, E. M.
1986-10-01
Analytical methods for solving boundary value problems for the heat conduction equation with heterogeneous boundary conditions on lines, on a plane, and in space are briefly reviewed. In particular, the method of dual integral equations and summator series is examined with reference to stationary processes. A table of principal solutions to dual integral equations and pair summator series is proposed which presents the known results in a systematic manner. Newly obtained results are presented in addition to the known ones.
Dual throat engine design for a SSTO launch vehicle
NASA Technical Reports Server (NTRS)
Obrien, C. J.; Salmon, J. W.
1980-01-01
A propulsion system analysis of a dual fuel, dual throat engine for launch vehicle application was conducted. Basic dual throat engine characterization data are presented to allow vehicle optimization studies to be conducted. A preliminary baseline engine system was defined. Dual throat engine performance, envelope, and weight parametric data were generated over the parametric range of thrust from 890 to 8896 KN (200K to 2M lb-force), chamber pressure from 6.89 million to 34.5 million N/sq m (1000 to 5000 psia) thrust ratio from 1.2 to 5, and a range of mixture ratios for the two tripropellant combinations: LO2/RP-1 + LH2 and LO2/LCH4 + LH2. The results of the study indicate that the dual fuel dual throat engine is a viable single stage to orbit candidate.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, W.W.; Layton, J.P.
1976-09-13
The three-volume report describes a dual-mode nuclear space power and propulsion system concept that employs an advanced solid-core nuclear fission reactor coupled via heat pipes to one of several electric power conversion systems. The NUROC3A systems analysis code was designed to provide the user with performance characteristics of the dual-mode system. Volume 3 describes utilization of the NUROC3A code to produce a detailed parameter study of the system.
Turk, Gregory C; Sharpless, Katherine E; Cleveland, Danielle; Jongsma, Candice; Mackey, Elizabeth A; Marlow, Anthony F; Oflaz, Rabia; Paul, Rick L; Sieber, John R; Thompson, Robert Q; Wood, Laura J; Yu, Lee L; Zeisler, Rolf; Wise, Stephen A; Yen, James H; Christopher, Steven J; Day, Russell D; Long, Stephen E; Greene, Ella; Harnly, James; Ho, I-Pin; Betz, Joseph M
2013-01-01
Standard Reference Material 3280 Multivitamin/ Multielement Tablets was issued by the National Institute of Standards and Technology in 2009, and has certified and reference mass fraction values for 13 vitamins, 26 elements, and two carotenoids. Elements were measured using two or more analytical methods at NIST with additional data contributed by collaborating laboratories. This reference material is expected to serve a dual purpose: to provide quality assurance in support of a database of dietary supplement products and to provide a means for analysts, dietary supplement manufacturers, and researchers to assess the appropriateness and validity of their analytical methods and the accuracy of their results.
NASA Astrophysics Data System (ADS)
Jerbi, Chahir; Fourno, André; Noetinger, Benoit; Delay, Frederick
2017-05-01
Single and multiphase flows in fractured porous media at the scale of natural reservoirs are often handled by resorting to homogenized models that avoid the heavy computations associated with a complete discretization of both fractures and matrix blocks. For example, the two overlapping continua (fractures and matrix) of a dual porosity system are coupled by way of fluid flux exchanges that deeply condition flow at the large scale. This characteristic is a key to realistic flow simulations, especially for multiphase flow as capillary forces and contrasts of fluid mobility compete in the extraction of a fluid from a capacitive matrix then conveyed through the fractures. The exchange rate between fractures and matrix is conditioned by the so-called mean matrix block size which can be viewed as the size of a single matrix block neighboring a single fracture within a mesh of a dual porosity model. We propose a new evaluation of this matrix block size based on the analysis of discrete fracture networks. The fundaments rely upon establishing at the scale of a fractured block the equivalence between the actual fracture network and a Warren and Root network only made of three regularly spaced fracture families parallel to the facets of the fractured block. The resulting matrix block sizes are then compared via geometrical considerations and two-phase flow simulations to the few other available methods. It is shown that the new method is stable in the sense it provides accurate sizes irrespective of the type of fracture network investigated. The method also results in two-phase flow simulations from dual porosity models very close to that from references calculated in finely discretized networks. Finally, calculations of matrix block sizes by this new technique reveal very rapid, which opens the way to cumbersome applications such as preconditioning a dual porosity approach applied to regional fractured reservoirs.
Single vs. dual color fire detection systems: operational tradeoffs
NASA Astrophysics Data System (ADS)
Danino, Meir; Danan, Yossef; Sinvani, Moshe
2017-10-01
In attempt to supply a reasonable fire plume detection, multinational cooperation with significant capital is invested in the development of two major Infra-Red (IR) based fire detection alternatives, single-color IR (SCIR) and dual-color IR (DCIR). False alarm rate was expected to be high not only as a result of real heat sources but mainly due to the IR natural clutter especially solar reflections clutter. SCIR uses state-of-the-art technology and sophisticated algorithms to filter out threats from clutter. On the other hand, DCIR are aiming at using additional spectral band measurements (acting as a guard), to allow the implementation of a simpler and more robust approach for performing the same task. In this paper we present the basics of SCIR & DCIR architecture and the main differences between them. In addition, we will present the results from a thorough study conducted for the purpose of learning about the added value of the additional data available from the second spectral band. Here we consider the two CO2 bands of 4-5 micron and of 2.5-3 micron band as well as off peak band (guard). The findings of this study refer also to Missile warning systems (MWS) efficacy, in terms of operational value. We also present a new approach for tunable filter to such sensor.
High-accuracy self-calibration method for dual-axis rotation-modulating RLG-INS
NASA Astrophysics Data System (ADS)
Wei, Guo; Gao, Chunfeng; Wang, Qi; Wang, Qun; Long, Xingwu
2017-05-01
Inertial navigation system has been the core component of both military and civil navigation systems. Dual-axis rotation modulation can completely eliminate the inertial elements constant errors of the three axes to improve the system accuracy. But the error caused by the misalignment angles and the scale factor error cannot be eliminated through dual-axis rotation modulation. And discrete calibration method cannot fulfill requirements of high-accurate calibration of the mechanically dithered ring laser gyroscope navigation system with shock absorbers. This paper has analyzed the effect of calibration error during one modulated period and presented a new systematic self-calibration method for dual-axis rotation-modulating RLG-INS. Procedure for self-calibration of dual-axis rotation-modulating RLG-INS has been designed. The results of self-calibration simulation experiment proved that: this scheme can estimate all the errors in the calibration error model, the calibration precision of the inertial sensors scale factor error is less than 1ppm and the misalignment is less than 5″. These results have validated the systematic self-calibration method and proved its importance for accuracy improvement of dual -axis rotation inertial navigation system with mechanically dithered ring laser gyroscope.
The Minkowski sum of a zonotope and the Voronoi polytope of the root lattice E{sub 7}
DOE Office of Scientific and Technical Information (OSTI.GOV)
Grishukhin, Vyacheslav P
2012-11-30
We show that the Minkowski sum P{sub V}(E{sub 7})+Z(U) of the Voronoi polytope P{sub V}(E{sub 7}) of the root lattice E{sub 7} and the zonotope Z(U) is a 7-dimensional parallelohedron if and only if the set U consists of minimal vectors of the dual lattice E{sub 7}{sup *} up to scalar multiplication, and U does not contain forbidden sets. The minimal vectors of E{sub 7} are the vectors r of the classical root system E{sub 7}. If the r{sup 2}-norm of the roots is set equal to 2, then the scalar products of minimal vectors from the dual lattice onlymore » take the values {+-}1/2. A set of minimal vectors is referred to as forbidden if it consists of six vectors, and the directions of some of these vectors can be changed so as to obtain a set of six vectors with all the pairwise scalar products equal to 1/2. Bibliography: 11 titles.« less
Saunders, Gabrielle H; Echt, Katharina V
2012-01-01
Combat exposures to blast can result in both peripheral damage to the ears and eyes and central damage to the auditory and visual processing areas in the brain. The functional effects of the latter include visual, auditory, and cognitive processing difficulties that manifest as deficits in attention, memory, and problem solving--symptoms similar to those seen in individuals with visual and auditory processing disorders. Coexisting damage to the auditory and visual system is referred to as dual sensory impairment (DSI). The number of Operation Iraqi Freedom/Operation Enduring Freedom Veterans with DSI is vast; yet currently no established models or guidelines exist for assessment, rehabilitation, or service-delivery practice. In this article, we review the current state of knowledge regarding blast exposure and DSI and outline the many unknowns in this area. Further, we propose a model for clinical assessment and rehabilitation of blast-related DSI that includes development of a coordinated team-based approach to target activity limitations and participation restrictions in order to enhance reintegration, recovery, and quality of life.
Dual- versus single-coil implantable defibrillator leads: review of the literature.
Neuzner, Jörg; Carlsson, Jörg
2012-04-01
The preferred use of dual-coil implantable defibrillator lead systems in current implantable defibrillator therapy is likely based on data showing statistically lower defibrillation thresholds with dual-coil defibrillator lead systems. The following review will summarize the clinical data for dual- versus single-coil defibrillator leads in the left and right pectoral implant locations, and will then discuss the clinical implications of single- versus dual-coil usage for atrial defibrillation, venous complications, and the risks associated with lead extraction. It will be noted that there are no comparative clinical studies on the use and outcomes of single- versus dual-coil lead systems in implantable defibrillator therapy over a long-term follow-up. The limited long-term reliability of defibrillator leads is a major concern in implantable defibrillator and cardiac resynchronization therapy. A simpler single-coil defibrillator lead system may improve the long-term performance of implanted leads. Furthermore, the superior vena cava coil is suspected to increase interventional risk in transvenous lead extraction. Therefore, the need for objective data on extractions and complications will be emphasized.
A dual sensor for real-time monitoring of glucose and oxygen
Zhang, Liqiang; Su, Fengyu; Buizer, Sean; Lu, Hongguang; Gao, Weimin; Tian, Yanqing; Meldrum, Deirdre
2013-01-01
A dual glucose and oxygen sensor in a polymer format was developed. The dual sensor composed of a blue emitter as the glucose probe, a red emitter as an oxygen probe, and a yellow emitter as a built-in reference probe which does not respond to either glucose or oxygen. All the three probes were chemically immobilized in a polyacrylamide-based matrix. Therefore, the dual sensor possesses three well separated emission colors and ratiometric approach is applicable for analysis of the glucose and oxygen concentration at biological conditions. The sensor was applied for real-time monitoring of glucose and oxygen consumption of bacterial cells, Escherichia coli (E. coli) and Bacillus subtilis (B. subtilis), and mammalian cells of mouse macrophage J774 and human cervical cancer HeLa cell lines. On the other hand, in order to achieve satisfactory sensing performance for glucose, compositions of the matrices among poly(2-hydroxyethyl methacrylate), polyacrylamide, and poly(6-aminohexyl methacrylamide) which is a linker polymer for grafting the glucose probe, were optimized. PMID:24090834
ERIC Educational Resources Information Center
Gessler, Michael
2017-01-01
The apprenticeship system in Germany is carried out both by companies and vocational schools (the Dual System). The question of whether the German Dual System is transferable is currently being asked in vocational education and training research. The analysis of current transfer discourses alludes to a research desideratum: the actual approaches…
Managerial Support for Dual-Career Relocation Dilemmas.
ERIC Educational Resources Information Center
Eby, Lillian T.; Douthitt, Shane S.; Perrin, Towers; Noble, Carrie L.; Atchley, Kate P.; Ladd, Robert T.
2002-01-01
Managers (n=143) completed a simulation exercise involving requests for employment assistance for the spouses of relocating employees. About one-third authorized specific actions. However, managers offered more extensive assistance to the spouses of female employees. (Contains 60 references.) (SK)
46 CFR 129.326 - Dual-voltage generators.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 4 2013-10-01 2013-10-01 false Dual-voltage generators. 129.326 Section 129.326 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Power Sources and Distribution Systems § 129.326 Dual-voltage generators. If a dual-voltage...
46 CFR 129.326 - Dual-voltage generators.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 4 2012-10-01 2012-10-01 false Dual-voltage generators. 129.326 Section 129.326 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Power Sources and Distribution Systems § 129.326 Dual-voltage generators. If a dual-voltage...
46 CFR 129.326 - Dual-voltage generators.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 4 2014-10-01 2014-10-01 false Dual-voltage generators. 129.326 Section 129.326 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Power Sources and Distribution Systems § 129.326 Dual-voltage generators. If a dual-voltage...
46 CFR 129.326 - Dual-voltage generators.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 4 2011-10-01 2011-10-01 false Dual-voltage generators. 129.326 Section 129.326 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS Power Sources and Distribution Systems § 129.326 Dual-voltage generators. If a dual-voltage...
2012-01-01
Introduction The purpose of this study was to compare the diagnostic accuracy of dual-energy contrast-enhanced digital mammography (CEDM) as an adjunct to mammography (MX) ± ultrasonography (US) with the diagnostic accuracy of MX ± US alone. Methods One hundred ten consenting women with 148 breast lesions (84 malignant, 64 benign) underwent two-view dual-energy CEDM in addition to MX and US using a specially modified digital mammography system (Senographe DS, GE Healthcare). Reference standard was histology for 138 lesions and follow-up for 12 lesions. Six radiologists from 4 institutions interpreted the images using high-resolution softcopy workstations. Confidence of presence (5-point scale), probability of cancer (7-point scale), and BI-RADS scores were evaluated for each finding. Sensitivity, specificity and ROC curve areas were estimated for each reader and overall. Visibility of findings on MX ± CEDM and MX ± US was evaluated with a Likert scale. Results The average per-lesion sensitivity across all readers was significantly higher for MX ± US ± CEDM than for MX ± US (0.78 vs. 0.71 using BIRADS, p = 0.006). All readers improved their clinical performance and the average area under the ROC curve was significantly superior for MX ± US ± CEDM than for MX ± US ((0.87 vs 0.83, p = 0.045). Finding visibility was similar or better on MX ± CEDM than MX ± US in 80% of cases. Conclusions Dual-energy contrast-enhanced digital mammography as an adjunct to MX ± US improves diagnostic accuracy compared to MX ± US alone. Addition of iodinated contrast agent to MX facilitates the visualization of breast lesions. PMID:22697607
NASA Astrophysics Data System (ADS)
Schonberg, William P.
1993-04-01
Results are presented from an experimental study in which Al dual-wall structures were tested, under various high-speed impact conditions, with a view to the effect of multilayer insulation thickness and location on perforation resistance. Attention is given to comparisons of the damage sustained by dual-wall systems with multilayer insulation blankets of various thicknesses and at various locations within the dual-wall system, under comparable impact loading conditions. The placement of the insulation has a significant effect on the ballistic limit of the dual-wall structures considered, while reducing insulation thickness by as much as a third did not.
NASA Astrophysics Data System (ADS)
Schonberg, William P.
Traditional perforation-resistant wall design for long-duration spacecraft consists of a "bumper" that is placed a small distance away from the main "pressure wall" of a spacecraft compartment or module. This concept has been studied extensively as a means of reducing the perforation threat of hypervelocity projectiles such as meteoroids and orbital debris. If a dual-wall system is employed on an earth-orbiting spacecraft, then a blanket of multi-layer insulation (MLI) will typically be included within the dual-wall system for thermal protection purposes. This paper presents the results of an experimental study in which aluminum dual-wall structures were tested under a variety of high-speed impact conditions to study the effect of MLI thickness and location on perforation resistance. The results presented consist of test-by-test comparisons of the damage sustained by similar dual-wall systems with blanket MLI of various thicknesses and at various locations within the dual-wall systems under similar impact loading conditions. The analyses performed revealed that the placement of the MLI had a significant effect on the ballistic limit of the dual-wall structures considered while reducing the thickness of the MLI by as much as 1/3 did not.
Lundin, Margareta; Lidén, Mats; Magnuson, Anders; Mohammed, Ahmed Abdulilah; Geijer, Håkan; Andersson, Torbjörn; Persson, Anders
2012-07-01
Dual-energy computed tomography (DECT) has been shown to be useful for subtracting bone or calcium in CT angiography and gives an opportunity to produce a virtual non-contrast-enhanced (VNC) image from a series where contrast agents have been given intravenously. High noise levels and low resolution have previously limited the diagnostic value of the VNC images created with the first generation of DECT. With the recent introduction of a second generation of DECT, there is a possibility of obtaining VNC images with better image quality at hopefully lower radiation dose compared to the previous generation. To compare the image quality of the single-energy series to a VNC series obtained with a two generations of DECT scanners. CT of the urinary tract was used as a model. Thirty patients referred for evaluation of hematuria were examined with an older system (Somatom Definition) and another 30 patients with a new generation (Somatom Definition Flash). One single-energy series was obtained before and one dual-energy series after administration of intravenous contrast media. We created a VNC series from the contrast-enhanced images. Images were assessed concerning image quality with a visual grading scale evaluation of the VNC series with the single-energy series as gold standard. The image quality of the VNC images was rated inferior to the single-energy variant for both scanners, OR 11.5-67.3 for the Definition and OR 2.1-2.8 for the Definition Flash. Visual noise and overall quality were regarded as better with Flash than Definition. Image quality of VNC images obtained with the new generation of DECT is still slightly inferior compared to native images. However, the difference is smaller with the new compared to the older system.
Arrhythmia discrimination by physician and defibrillator: importance of atrial channel.
Diemberger, Igor; Martignani, Cristian; Biffi, Mauro; Frabetti, Lorenzo; Valzania, Cinzia; Cooke, Robin M T; Rapezzi, Claudio; Branzi, Angelo; Boriani, Giuseppe
2012-01-26
Many ICD carriers experience inappropriate shocks, but the relative merits of dual- /single-chamber devices for arrhythmia discrimination still remain unclear. We explored possible advantages of the atrial data provided by dual-chamber implantable defibrillators (ICD) for discrimination of real-life supraventricular/ventricular tachyarrhythmias (SVT/VT). 100 dual-chamber traces from 24 ICD were blindly reviewed in dual-chamber and simulated single-chamber (with/without discriminator data) reading modes by five electrophysiologists who determined chamber of origin and provided Likert-scale "confidence" ratings. We assessed 1) intra/interobserver concordance; 2) diagnostic accuracy, using expert diagnoses as a reference standard; 3) ROC curves of sensitivity/specificity of "likelihood perception" scores, generated by combining chamber-of-origin diagnostic judgments with Likert-scale "confidence" ratings. We also assessed diagnostic accuracy of automated discrimination by all possible dual-/single-chamber algorithm configurations. Interobserver concordance was "substantial" (modified Cohen kappa-test values for dual-/single-chamber, 0.79/0.68); intraobserver concordance "almost complete" (kappa ≥ 0.89). Dual-chamber mode provided best diagnostic sensitivity/specificity (99%/92%) and highest reader confidence (p<0.001). Area under ROC curves of sensitivity/specificity values for the "likelihood perception" score (representing electrophysiologists' perceptions of the likelihood that an episode was of ventricular origin) was highest in dual-chamber mode (0.98 vs. 0.93 for both single-chamber modes; p<0.001). Regarding automated discrimination, all four dual-chamber configurations conferred 100% sensitivity (specificity values ranged 39%-88%), whereas single-chamber configurations appeared inferior (best sensitivity/specificity combination, 89%/64%). Availability of the atrial channel helps in reducing inappropriate ICD therapies by providing relevant advantages in terms of both appropriate cardiologist's post-hoc discrimination of SVT/VT (improving program tailoring) and automated arrhythmia discrimination. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
p16/Ki-67 Dual Stain Cytology for Detection of Cervical Precancer in HPV-Positive Women
Fetterman, Barbara; Castle, Philip E.; Schiffman, Mark; Wood, Shannon N.; Stiemerling, Eric; Tokugawa, Diane; Bodelon, Clara; Poitras, Nancy; Lorey, Thomas; Kinney, Walter
2015-01-01
Background: Human papillomavirus (HPV)–based cervical cancer screening requires triage markers to decide who should be referred to colposcopy. p16/Ki-67 dual stain cytology has been proposed as a biomarker for cervical precancers. We evaluated the dual stain in a large population of HPV-positive women. Methods: One thousand five hundred and nine HPV-positive women screened with HPV/cytology cotesting at Kaiser Permanente California were enrolled into a prospective observational study in 2012. Dual stain cytology was performed on residual Surepath material, and slides were evaluated for dual stain–positive cells. Disease endpoints were ascertained from the clinical database at KPNC. We evaluated the clinical performance of the assay among all HPV-positive women and among HPV-positive, cytology-negative women. We used internal benchmarks for clinical management to evaluate the clinical relevance of the dual stain assay. We evaluated sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the dual stain compared with Pap cytology. All statistical tests were two-sided. Results: The dual stain had lower positivity (45.9%) compared with cytology at an ASC-US threshold (53.4%). For detection of CIN2+, the dual stain had similar sensitivity (83.4% vs 76.6%, P = .1), and statistically higher specificity (58.9% vs 49.6%, P < .001), PPV (21.0% vs 16.6%, P < .001), and NPV (96.4% vs 94.2%, P = .01) compared with cytology. Similar patterns were observed for CIN3+. Women with a positive test had high enough risk for referral to colposcopy, while the risk for women with negative tests was below a one-year return threshold based on current US management guidelines. Conclusion: Dual stain cytology showed good risk stratification for all HPV-positive women and for HPV-positive women with normal cytology. Additional follow-up is needed to determine how long dual stain negative women remain at low risk of precancer. PMID:26376685
Pänkäälä, Mikko; Paasio, Ari
2014-01-01
Both respiratory and cardiac motions reduce the quality and consistency of medical imaging specifically in nuclear medicine imaging. Motion artifacts can be eliminated by gating the image acquisition based on the respiratory phase and cardiac contractions throughout the medical imaging procedure. Electrocardiography (ECG), 3-axis accelerometer, and respiration belt data were processed and analyzed from ten healthy volunteers. Seismocardiography (SCG) is a noninvasive accelerometer-based method that measures accelerations caused by respiration and myocardial movements. This study was conducted to investigate the feasibility of the accelerometer-based method in dual gating technique. The SCG provides accelerometer-derived respiratory (ADR) data and accurate information about quiescent phases within the cardiac cycle. The correct information about the status of ventricles and atria helps us to create an improved estimate for quiescent phases within a cardiac cycle. The correlation of ADR signals with the reference respiration belt was investigated using Pearson correlation. High linear correlation was observed between accelerometer-based measurement and reference measurement methods (ECG and Respiration belt). Above all, due to the simplicity of the proposed method, the technique has high potential to be applied in dual gating in clinical cardiac positron emission tomography (PET) to obtain motion-free images in the future. PMID:25120563
Koch, Iring; Poljac, Edita; Müller, Hermann; Kiesel, Andrea
2018-06-01
Numerous studies showed decreased performance in situations that require multiple tasks or actions relative to appropriate control conditions. Because humans often engage in such multitasking activities, it is important to understand how multitasking affects performance. In the present article, we argue that research on dual-task interference and sequential task switching has proceeded largely separately using different experimental paradigms and methodology. In our article we aim at organizing this complex set of research in terms of three complementary research perspectives on human multitasking. One perspective refers to structural accounts in terms of cognitive bottlenecks (i.e., critical processing stages). A second perspective refers to cognitive flexibility in terms of the underlying cognitive control processes. A third perspective emphasizes cognitive plasticity in terms of the influence of practice on human multitasking abilities. With our review article we aimed at highlighting the value of an integrative position that goes beyond isolated consideration of a single theoretical research perspective and that broadens the focus from single experimental paradigms (dual task and task switching) to favor instead a view that emphasizes the fundamental similarity of the underlying cognitive mechanisms across multitasking paradigms. (PsycINFO Database Record (c) 2018 APA, all rights reserved).
Microwave time delays for the dual L-C-band feed system
NASA Technical Reports Server (NTRS)
Chen, J.
1989-01-01
A new dual-frequency feed system at Goldstone is designed to receive the Phobos spacecraft signal at L-band (1668 + or - 40 MHz) and transmit to the spacecraft at C-band (5008.75 + or - 5.00 MHz) simultaneously. Hence, calculations of the time delay from the C-band range calibration coupler to the phase center of the L-C dual feed and back to the L-band range calibration coupler are required to correct the range measurements. Time delays of the elements in the dual-frequency feed system are obtained mostly from computer calculations and partly from experimental measurements. The method used and results obtained are described.
Risen, Jane L
2016-03-01
Traditionally, research on superstition and magical thinking has focused on people's cognitive shortcomings, but superstitions are not limited to individuals with mental deficits. Even smart, educated, emotionally stable adults have superstitions that are not rational. Dual process models--such as the corrective model advocated by Kahneman and Frederick (2002, 2005), which suggests that System 1 generates intuitive answers that may or may not be corrected by System 2--are useful for illustrating why superstitious thinking is widespread, why particular beliefs arise, and why they are maintained even though they are not true. However, to understand why superstitious beliefs are maintained even when people know they are not true requires that the model be refined. It must allow for the possibility that people can recognize--in the moment--that their belief does not make sense, but act on it nevertheless. People can detect an error, but choose not to correct it, a process I refer to as acquiescence. The first part of the article will use a dual process model to understand the psychology underlying magical thinking, highlighting features of System 1 that generate magical intuitions and features of the person or situation that prompt System 2 to correct them. The second part of the article will suggest that we can improve the model by decoupling the detection of errors from their correction and recognizing acquiescence as a possible System 2 response. I suggest that refining the theory will prove useful for understanding phenomena outside of the context of magical thinking. (c) 2016 APA, all rights reserved).
Dual redundant arm system operational quality measures and their applications - Dynamic measures
NASA Technical Reports Server (NTRS)
Lee, Sukhan; Kim, Sungbok
1990-01-01
Dual-arm dynamic operation quality measures are presented which quantify the efficiency and capability of generating Cartesian accelerations by two cooperative arms based on the analysis of dual-arm dynamic interactions. Dual-arm dynamic manipulability is defined as the efficiency of generating Cartesian accelerations under the dynamic and kinematic interactions between individual arms and an object under manipulation. The analysis of dual-arm dynamic interactions is based on the so-called Cartesian space agent model of an arm, which represents an individual arm as a force source acting upon a point mass with the effective Cartesian space arm dynamics and an environment or an object under manipulation. The Cartesian space agent model of an arm makes it possible to derive the dynamic and kinematic constraints involved in the transport, assembly and grasping modes of dual-arm cooperation. A task-oriented operational quality measure, (TOQd) is defined by evaluating dual-arm dynamic manipulability in terms of given task requirements. TOQd is used in dual-arm joint configuration optimization. Simulation results are shown. A complete set of forward dynamic equations for a dual-arm system is derived, and dual-arm dynamic operational quality measures for various modes of dual-arm cooperation allowing sliding contacts are established.
Harvey, S Marie; Henderson, Jillian T; Branch, Meredith Roberts
2004-01-01
Although male condoms are the best form of protection against HIV/STDs, they are not the most effective method for preventing unintended pregnancy. Consequently, use of condoms and a highly effective contraceptive-referred to as dual use-is recommended as the optimal protection against both disease and pregnancy. However, little is known about the factors that promote dual use. This study examined associations of dual method use with women's background characteristics, intrapersonal factors, and relationship characteristics. Data are from a random sample of women selected from a large managed care organization in the Pacific Northwest. The analytic sample contained 371 women who completed a telephone survey and reported use of contraceptives in the past 3 months. Three mutually exclusive method use groups were constructed: effective contraceptive only (hormonal methods, intrauterine device, surgical sterilization) (59%), condom only (24%), and dual use (18%). Variables hypothesized to influence dual use were compared across the three groups in bivariate and multivariate analyses. Findings indicate that women who were younger, reported more than one sexual partner in the past year, and were highly motivated to avoid HIV/STDs--were more likely to use dual methods rather than condoms only or an effective contraceptive method. Women confident about using condoms without feeling embarrassed or breaking the sexual mood were more likely to use dual methods rather than a single effective method. Finally, women with confidence in their ability to use condoms correctly are more likely to rely solely on condoms. Policy and practice implications are discussed.
Ha, Yejin; Myung, Dongshin; Shim, Jun Ho; Kim, Myung Hwa; Lee, Youngmi
2013-09-21
In this study, a dual microsensing electrochemical probe for measuring oxygen (O2) and pH levels was developed based on a dual recessed Pt disk electrode (each disk diameter, 10 μm) with the use of two Ag/AgCl reference electrodes (one for each disk of the dual electrode). One of the recessed Pt disks of the dual electrode was electrodeposited with a porous Pt layer and then coated with a hydrophobic photocured polymer (partially fluorinated epoxy diacrylate, abbreviated as FED). The Pt-FED covered disk was used as an amperometric O2 sensor and exhibited a linear current increase that was proportional to the PO2 level (partial O2 pressure) with high sensitivity (168.4 ± 33.8 pA mmHg(-1)) and fast response time (t90% = 0.17 ± 0.05 s). The other recessed Pt disk was electrodeposited with an IrO2 layer. The potential between the IrO2 deposited electrode and the Ag/AgCl reference electrode produced a reliable Nernstian response to pH changes (58.3 ± 1.5 mV pH(-1)) with a t90% of 0.43 ± 0.09 s. The sensor displayed high stability in the in vitro organ tissue measurements for at least 2.5 h. By using the developed dual O2/pH microsensor as a probe tip for scanning electrochemical microscopy, the two-dimensional images of the location-dependent PO2 and pH levels were simultaneously acquired and could be used to assess the surface of a rat kidney tissue slice. When compared to the corresponding medullary levels, both PO2 and pH were observed to be higher in the cortex area, while the modest level gradient was observed near the cortex-medulla border. This finding suggests that there is a direct relationship between the tissue O2 supply/consumption and pH, which is mainly determined by metabolite, such as CO2, production.
Development of a dual-field heteropoplar power converter
NASA Technical Reports Server (NTRS)
Eisenhaure, D. B.; Johnson, B.; Bliamptis, T.; St. George, E.
1981-01-01
The design and testing of a 400 watt, dual phase, dual rotor, field modulated inductor alternator is described. The system is designed for use as a flywheel to ac utility line or flywheel to dc bus (electric vehicle) power converter. The machine is unique in that it uses dual rotors and separately controlled fields to produce output current and voltage which are in phase with each other. Having the voltage and current in phase allows the power electronics to be made of simple low cost components. Based on analytical predictions and experimental results, development of a complete 22 kilowatt (30 Hp) power conversion system is recommended. This system would include power electronics and controls and would replace the inductor alternator with an improved electromagnetic conversion system.
Dual frequency comb metrology with one fiber laser
NASA Astrophysics Data System (ADS)
Zhao, Xin; Takeshi, Yasui; Zheng, Zheng
2016-11-01
Optical metrology techniques based on dual optical frequency combs have emerged as a hotly studied area targeting a wide range of applications from optical spectroscopy to microwave and terahertz frequency measurement. Generating two sets of high-quality comb lines with slightly different comb-tooth spacings with high mutual coherence and stability is the key to most of the dual-comb schemes. The complexity and costs of such laser sources and the associated control systems to lock the two frequency combs hinder the wider adoption of such techniques. Here we demonstrate a very simple and rather different approach to tackle such a challenge. By employing novel laser cavity designs in a mode-locked fiber laser, a simple fiber laser setup could emit dual-comb pulse output with high stability and good coherence between the pulse trains. Based on such lasers, comb-tooth-resolved dual-comb optical spectroscopy is demonstrated. Picometer spectral resolving capability could be realized with a fiber-optic setup and a low-cost data acquisition system and standard algorithms. Besides, the frequency of microwave signals over a large range can be determined based on a simple setup. Our results show the capability of such single-fiber-laser-based dual-comb scheme to reduce the complexity and cost of dual-comb systems with excellent quality for different dual-comb applications.
Implementation of Size-Dependent Local Diagnostic Reference Levels for CT Angiography.
Boere, Hub; Eijsvoogel, Nienke G; Sailer, Anna M; Wildberger, Joachim E; de Haan, Michiel W; Das, Marco; Jeukens, Cecile R L P N
2018-05-01
Diagnostic reference levels (DRLs) are established for standard-sized patients; however, patient dose in CT depends on patient size. The purpose of this study was to introduce a method for setting size-dependent local diagnostic reference levels (LDRLs) and to evaluate these LDRLs in comparison with size-independent LDRLs and with respect to image quality. One hundred eighty-four aortic CT angiography (CTA) examinations performed on either a second-generation or third-generation dual-source CT scanner were included; we refer to the second-generation dual-source CT scanner as "CT1" and the third-generation dual-source CT scanner as "CT2." The volume CT dose index (CTDI vol ) and patient diameter (i.e., the water-equivalent diameter) were retrieved by dose-monitoring software. Size-dependent DRLs based on a linear regression of the CTDI vol versus patient size were set by scanner type. Size-independent DRLs were set by the 5th and 95th percentiles of the CTDI vol values. Objective image quality was assessed using the signal-to-noise ratio (SNR), and subjective image quality was assessed using a 4-point Likert scale. The CTDI vol depended on patient size and scanner type (R 2 = 0.72 and 0.78, respectively; slope = 0.05 and 0.02 mGy/mm; p < 0.001). Of the outliers identified by size-independent DRLs, 30% (CT1) and 67% (CT2) were adequately dosed when considering patient size. Alternatively, 30% (CT1) and 70% (CT2) of the outliers found with size-dependent DRLs were not identified using size-independent DRLs. A negative correlation was found between SNR and CTDI vol (R 2 = 0.36 for CT1 and 0.45 for CT2). However, all outliers had a subjective image quality score of sufficient or better. We introduce a method for setting size-dependent LDRLs in CTA. Size-dependent LDRLs are relevant for assessing the appropriateness of the radiation dose for an individual patient on a specific CT scanner.
Doctor of Nursing Practice and Doctor of Pharmacy Dual Degree Program Act of 2011
Sen. Inouye, Daniel K. [D-HI
2011-01-25
Senate - 01/25/2011 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Doctor of Nursing Practice and Doctor of Pharmacy Dual Degree Program Act of 2010
Sen. Inouye, Daniel K. [D-HI
2010-09-28
Senate - 09/28/2010 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Synthesis of monomethyl 5,5'-dehydrodiferulic acid
USDA-ARS?s Scientific Manuscript database
Synthesis of the internal reference compound, monomethyl 5,5’-dehydrodiferulic acid, is described. The synthetic scheme relies on a selective monomethylation of the known compound 5,5-dehydrodivanillin, followed by elaboration into the dehydrodiferulic framework through a dual Horner-Emmons-Wadswort...
46 CFR 183.324 - Dual voltage generators.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 7 2010-10-01 2010-10-01 false Dual voltage generators. 183.324 Section 183.324... TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.324 Dual voltage generators. (a) A dual voltage generator installed on a vessel shall be of the grounded type, where: (1) The...
Effect of Operating Parameters on a Dual-Stage High Velocity Oxygen Fuel Thermal Spray System
NASA Astrophysics Data System (ADS)
Khan, Mohammed N.; Shamim, Tariq
2014-08-01
High velocity oxygen fuel (HVOF) thermal spray systems are being used to apply coatings to prevent surface degradation. The coatings of temperature sensitive materials such as titanium and copper, which have very low melting points, cannot be applied using a single-stage HVOF system. Therefore, a dual-stage HVOF system has been introduced and modeled computationally. The dual-spray system provides an easy control of particle oxidation by introducing a mixing chamber. In addition to the materials being sprayed, the thermal spray coating quality depends to a large extent on flow behavior of reacting gases and the particle dynamics. The present study investigates the influence of various operating parameters on the performance of a dual-stage thermal spray gun. The objective is to develop a predictive understanding of various parameters. The gas flow field and the free jet are modeled by considering the conservation of mass, momentum, and energy with the turbulence and the equilibrium combustion sub models. The particle phase is decoupled from the gas phase due to very low particle volume fractions. The results demonstrate the advantage of a dual-stage system over a single-stage system especially for the deposition of temperature sensitive materials.
Braking System Integration in Dual Mode Systems
DOT National Transportation Integrated Search
1974-05-01
An optimal braking system for Dual Mode is a complex product of vast number of multivariate, interdependent parameters that encompass on-guideway and off-guideway operation as well as normal and emergency braking. : Details of, and interralations amo...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, H.; Higuchi, T.; Nishioki, N.
1997-01-01
A dual tunneling-unit scanning tunneling microscope (DTU STM) was developed for nm order length measurement with wide scan range. The crystalline lattice of highly oriented pyrolitic graphite (HOPG) was used as reference scale. A reference unit was set up on top of a test unit. The reference sample holder and the probe tip of test unit were attached to one single XY scanner on either surface, while the test sample holder was open. This enables simultaneous acquisition of wide images of HOPG and test sample. The length in test sample image was measured by counting the number of HOPG lattices.more » An inchworm actuator and an impact drive mechanism were introduced to roughly position probe tips. The XY scanner was designed to be elastic to eliminate image distortion. Some comparison experiments using two HOPG chips were carried out in air. The DTU STM is confirmed to be a stable and more powerful device for length measurement which has nanometer accuracy when covering a wide scan range up to several micrometers, and is capable of measuring comparatively large and heavy samples. {copyright} {ital 1997 American Vacuum Society.}« less
Thermodynamic analysis of a new dual evaporator CO2 transcritical refrigeration cycle
NASA Astrophysics Data System (ADS)
Abdellaoui, Ezzaalouni Yathreb; Kairouani, Lakdar Kairouani
2017-03-01
In this work, a new dual-evaporator CO2 transcritical refrigeration cycle with two ejectors is proposed. In this new system, we proposed to recover the lost energy of condensation coming off the gas cooler and operate the refrigeration cycle ejector free and enhance the system performance and obtain dual-temperature refrigeration simultaneously. The effects of some key parameters on the thermodynamic performance of the modified cycle are theoretically investigated based on energetic and exergetic analysis. The simulation results for the modified cycle indicate more effective system performance improvement than the single ejector in the CO2 vapor compression cycle using ejector as an expander ranging up to 46%. The exergetic analysis for this system is made. The performance characteristics of the proposed cycle show its promise in dual-evaporator refrigeration system.
Dual energy CT of the chest: how about the dose?
Schenzle, Jan C; Sommer, Wieland H; Neumaier, Klement; Michalski, Gisela; Lechel, Ursula; Nikolaou, Konstantin; Becker, Christoph R; Reiser, Maximilian F; Johnson, Thorsten R C
2010-06-01
New generation Dual Source computed tomography (CT) scanners offer different x-ray spectra for Dual Energy imaging. Yet, an objective, manufacturer independent verification of the dose required for the different spectral combinations is lacking. The aim of this study was to assess dose and image noise of 2 different Dual Energy CT settings with reference to a standard chest scan and to compare image noise and contrast to noise ratios (CNR). Also, exact effective dose length products (E/DLP) conversion factors were to be established based on the objectively measured dose. An anthropomorphic Alderson phantom was assembled with thermoluminescent detectors (TLD) and its chest was scanned on a Dual Source CT (Siemens Somatom Definition) in dual energy mode at 140 and 80 kVp with 14 x 1.2 mm collimation. The same was performed on another Dual Source CT (Siemens Somatom Definition Flash) at 140 kVp with 0.8 mm tin filter (Sn) and 100 kVp at 128 x 0.6 mm collimation. Reference scans were obtained at 120 kVp with 64 x 0.6 mm collimation at equivalent CT dose index of 5.4 mGy*cm. Syringes filled with water and 17.5 mg iodine/mL were scanned with the same settings. Dose was calculated from the TLD measurements and the dose length products of the scanner. Image noise was measured in the phantom scans and CNR and spectral contrast were determined in the iodine and water samples. E/DLP conversion factors were calculated as ratio between the measured dose form the TLDs and the dose length product given in the patient protocol. The effective dose measured with TLDs was 2.61, 2.69, and 2.70 mSv, respectively, for the 140/80 kVp, the 140 Sn/100 kVp, and the standard 120 kVp scans. Image noise measured in the average images of the phantom scans was 11.0, 10.7, and 9.9 HU (P > 0.05). The CNR of iodine with optimized image blending was 33.4 at 140/80 kVp, 30.7 at 140Sn/100 kVp and 14.6 at 120 kVp. E/DLP conversion factors were 0.0161 mSv/mGy*cm for the 140/80 kVp protocol, 0.0181 mSv/mGy*cm for the Sn140/100 kVp mode and 0.0180 mSv/mGy*cm for the 120 kVp examination. Dual Energy CT is feasible without additional dose. There is no significant difference in image noise, while CNR can be doubled with optimized dual energy CT reconstructions. A restriction in collimation is required for dose-neutrality at 140/80 kVp, whereas this is not necessary at 140 Sn/100 kVp. Thus, CT can be performed routinely in Dual Energy mode without additional dose or compromises in image quality.
Dual nozzle aerodynamic and cooling analysis study. [dual throat and dual expander nozzles
NASA Technical Reports Server (NTRS)
Meagher, G. M.
1980-01-01
Geometric, aerodynamic flow field, performance prediction, and heat transfer analyses are considered for two advanced chamber nozzle concepts applicable to Earth-to-orbit engine systems. Topics covered include improvements to the dual throat aerodynamic and performance prediction program; geometric and flow field analyses of the dual expander concept; heat transfer analysis of both concepts, and engineering analysis of data from the NASA/MSFC hot-fire testing of a dual throat thruster model thrust chamber assembly. Preliminary results obtained are presented in graphs.
ERIC Educational Resources Information Center
Weale, Gillian
2010-01-01
Since the start of the academic session 2007-08, the University of Exeter has been operating a unique system of governance known as dual assurance, which has replaced a more traditional system of committees sitting under Council, the governing body. This paper describes the background to the development of dual assurance at Exeter, and the reasons…
Chang, Ye; Hui, Zhipeng; Wang, Xiayu; Qu, Hemi; Pang, Wei
2018-01-01
In this paper, we develop a novel dual-mode gas sensor system which comprises a silicon nanoribbon field effect transistor (Si-NR FET) and a film bulk acoustic resonator (FBAR). We investigate their sensing characteristics using polar and nonpolar organic compounds, and demonstrate that polarity has a significant effect on the response of the Si-NR FET sensor, and only a minor effect on the FBAR sensor. In this dual-mode system, qualitative discrimination can be achieved by analyzing polarity with the Si-NR FET and quantitative concentration information can be obtained using a polymer-coated FBAR with a detection limit at the ppm level. The complementary performance of the sensing elements provides higher analytical efficiency. Additionally, a dual mixture of two types of freons (CFC-113 and HCFC-141b) is further analyzed with the dual-mode gas sensor. Owing to the small size and complementary metal-oxide semiconductor (CMOS)-compatibility of the system, the dual-mode gas sensor shows potential as a portable integrated sensing system for the analysis of gas mixtures in the future. PMID:29370109
Chang, Ye; Hui, Zhipeng; Wang, Xiayu; Qu, Hemi; Pang, Wei; Duan, Xuexin
2018-01-25
In this paper, we develop a novel dual-mode gas sensor system which comprises a silicon nanoribbon field effect transistor (Si-NR FET) and a film bulk acoustic resonator (FBAR). We investigate their sensing characteristics using polar and nonpolar organic compounds, and demonstrate that polarity has a significant effect on the response of the Si-NR FET sensor, and only a minor effect on the FBAR sensor. In this dual-mode system, qualitative discrimination can be achieved by analyzing polarity with the Si-NR FET and quantitative concentration information can be obtained using a polymer-coated FBAR with a detection limit at the ppm level. The complementary performance of the sensing elements provides higher analytical efficiency. Additionally, a dual mixture of two types of freons (CFC-113 and HCFC-141b) is further analyzed with the dual-mode gas sensor. Owing to the small size and complementary metal-oxide semiconductor (CMOS)-compatibility of the system, the dual-mode gas sensor shows potential as a portable integrated sensing system for the analysis of gas mixtures in the future.
NASA Astrophysics Data System (ADS)
Zhang, Wen; Hao, Jiaqi; Lou, Xiaoping; Dong, Mingli; Zhu, Lianqing
2018-03-01
An all-fiber dual-parameter sensor based on cascaded long period grating pair fabricated by femtosecond laser and CO2 laser has been proposed and realized both theoretically and experimentally. The resonant wavelengths of LPFGs are 1557.80 nm and 1590.88 nm. In the strain range of 0-400 με, strain sensitivities are -7.2 pm/με for C-LPFG and -1.6 pm/με for F-LPFG. In the temperature range of 30-70°C, temperature sensitivities are -41.1 pm/°C for C-LPFG and -21.2 pm/°C for F-LPFG. By analyzing the resonant wavelength characterization, the proposed sensor can be efficiently used for dual-parameters measurement with promising application prospect and great research reference value.
Gelatt, Julia
2013-01-01
Foundational theories of international migration rest on the assumption that immigrants maintain reference groups in their country of origin even after settling in a new place, while the transnationalism perspective suggests that immigrants maintain a dual frame of reference. This paper uses the nationally-representative National Latino and Asian American Survey to test the location of immigrants’ reference groups. I find that the relationship between various measures of subjective social standing and subjective well-being suggests that immigrants maintain simultaneous reference groups in both the United States and the country of origin, supporting transnational theories, and refuting earlier theories. PMID:24151347
Agricultural Land Cover from Multitemporal C-Band SAR Data
NASA Astrophysics Data System (ADS)
Skriver, H.
2013-12-01
Henning Skriver DTU Space, Technical University of Denmark Ørsteds Plads, Building 348, DK-2800 Lyngby e-mail: hs@space.dtu.dk Problem description This paper focuses on land cover type from SAR data using high revisit acquisitions, including single and dual polarisation and fully polarimetric data, at C-band. The data set were acquired during an ESA-supported campaign, AgriSAR09, with the Radarsat-2 system. Ground surveys to obtain detailed land cover maps were performed during the campaign. Classification methods using single- and dual-polarisation data, and fully polarimetric data are used with multitemporal data with short revisit time. Results for airborne campaigns have previously been reported in Skriver et al. (2011) and Skriver (2012). In this paper, the short revisit satellite SAR data will be used to assess the trade-off between polarimetric SAR data and data as single or dual polarisation SAR data. This is particularly important in relation to the future GMES Sentinel-1 SAR satellites, where two satellites with a relatively wide swath will ensure a short revisit time globally. Questions dealt with are: which accuracy can we expect from a mission like the Sentinel-1, what is the improvement of using polarimetric SAR compared to single or dual polarisation SAR, and what is the optimum number of acquisitions needed. Methodology The data have sufficient number of looks for the Gaussian assumption to be valid for the backscatter coefficients for the individual polarizations. The classification method used for these data is therefore the standard Bayesian classification method for multivariate Gaussian statistics. For the full-polarimetric cases two classification methods have been applied, the standard ML Wishart classifier, and a method based on a reversible transform of the covariance matrix into backscatter intensities. The following pre-processing steps were performed on both data sets: The scattering matrix data in the form of SLC products were coregistered, converted to covariance matrix format and multilooked to a specific equivalent number of looks. Results The multitemporal data improve significantly the classification results, and single acquisition data cannot provide the necessary classification performance. The multitemporal data are especially important for the single and dual polarization data, but less important for the fully polarimetric data. The satellite data set produces realistic classification results based on about 2000 fields. The best classification results for the single-polarized mode provide classification errors in the mid-twenties. Using the dual-polarized mode reduces the classification error with about 5 percentage points, whereas the polarimetric mode reduces it with about 10 percentage points. These results show, that it will be possible to obtain reasonable results with relatively simple systems with short revisit time. This very important result shows that systems like the Sentinel-1 mission will be able to produce fairly good results for global land cover classification. References Skriver, H. et al., 2011, 'Crop Classification using Short-Revisit Multitemporal SAR Data', IEEE J. Sel. Topics in Appl. Earth Obs. Rem. Sens., vol. 4, pp. 423-431. Skriver, H., 2012, 'Crop classification by multitemporal C- and L-band single- and dual-polarization and fully polarimetric SAR', IEEE Trans. Geosc. Rem. Sens., vol. 50, pp. 2138-2149.
Dual-comb spectroscopy of water vapor with a free-running semiconductor disk laser.
Link, S M; Maas, D J H C; Waldburger, D; Keller, U
2017-06-16
Dual-comb spectroscopy offers the potential for high accuracy combined with fast data acquisition. Applications are often limited, however, by the complexity of optical comb systems. Here we present dual-comb spectroscopy of water vapor using a substantially simplified single-laser system. Very good spectroscopy measurements with fast sampling rates are achieved with a free-running dual-comb mode-locked semiconductor disk laser. The absolute stability of the optical comb modes is characterized both for free-running operation and with simple microwave stabilization. This approach drastically reduces the complexity for dual-comb spectroscopy. Band-gap engineering to tune the center wavelength from the ultraviolet to the mid-infrared could optimize frequency combs for specific gas targets, further enabling dual-comb spectroscopy for a wider range of industrial applications. Copyright © 2017, American Association for the Advancement of Science.
Nursing home 5-star rating system exacerbates disparities in quality, by payer source.
Konetzka, R Tamara; Grabowski, David C; Perraillon, Marcelo Coca; Werner, Rachel M
2015-05-01
Market-based reforms in health care, such as public reporting of quality, may inadvertently exacerbate disparities. We examined how the Centers for Medicare and Medicare Services' five-star rating system for nursing homes has affected residents who are dually enrolled in Medicare and Medicaid ("dual eligibles"), a particularly vulnerable and disadvantaged population. Specifically, we assessed the extent to which dual eligibles and non-dual eligibles avoided the lowest-rated nursing homes and chose the highest-rated homes once the five-star rating system began, in late 2008. We found that both populations resided in better-quality homes over time but that by 2010 the increased likelihood of choosing the highest-rated homes was substantially smaller for dual eligibles than for non-dual eligibles. Thus, the gap in quality, as measured by a nursing home's star rating, grew over time. Furthermore, we found that the benefit of the five-star system to dual eligibles was largely due to providers' improving their ratings, not to consumers' choosing different providers. We present evidence suggesting that supply constraints play a role in limiting dual eligibles' responses to quality ratings, since high-quality providers tend to be located close to relatively affluent areas. Increases in Medicaid payment rates for nursing home services may be the only long-term solution. Project HOPE—The People-to-People Health Foundation, Inc.
Comparison study of noise reduction algorithms in dual energy chest digital tomosynthesis
NASA Astrophysics Data System (ADS)
Lee, D.; Kim, Y.-S.; Choi, S.; Lee, H.; Choi, S.; Kim, H.-J.
2018-04-01
Dual energy chest digital tomosynthesis (CDT) is a recently developed medical technique that takes advantage of both tomosynthesis and dual energy X-ray images. However, quantum noise, which occurs in dual energy X-ray images, strongly interferes with diagnosis in various clinical situations. Therefore, noise reduction is necessary in dual energy CDT. In this study, noise-compensating algorithms, including a simple smoothing of high-energy images (SSH) and anti-correlated noise reduction (ACNR), were evaluated in a CDT system. We used a newly developed prototype CDT system and anthropomorphic chest phantom for experimental studies. The resulting images demonstrated that dual energy CDT can selectively image anatomical structures, such as bone and soft tissue. Among the resulting images, those acquired with ACNR showed the best image quality. Both coefficient of variation and contrast to noise ratio (CNR) were the highest in ACNR among the three different dual energy techniques, and the CNR of bone was significantly improved compared to the reconstructed images acquired at a single energy. This study demonstrated the clinical value of dual energy CDT and quantitatively showed that ACNR is the most suitable among the three developed dual energy techniques, including standard log subtraction, SSH, and ACNR.
Theoretical study of a dual harmonic system and its application to the CSNS/RCS
NASA Astrophysics Data System (ADS)
Yuan, Yao-Shuo; Wang, Na; Xu, Shou-Yan; Yuan, Yue; Wang, Sheng
2015-12-01
Dual harmonic systems have been widely used in high intensity proton synchrotrons to suppress the space charge effect, as well as reduce the beam loss. To investigate the longitudinal beam dynamics in a dual rf system, the potential well, the sub-buckets in the bunch and the multi-solutions of the phase equation are studied theoretically in this paper. Based on these theoretical studies, optimization of bunching factor and rf voltage waveform are made for the dual harmonic rf system in the upgrade phase of the China Spallation Neutron Source Rapid Cycling Synchrotron (CSNS/RCS). In the optimization process, the simulation with space charge effect is done using a newly developed code, C-SCSIM. Supported by National Natural Science Foundation of China (11175193)
Pitfalls in the measurement of muscle mass: a need for a reference standard.
Buckinx, Fanny; Landi, Francesco; Cesari, Matteo; Fielding, Roger A; Visser, Marjolein; Engelke, Klaus; Maggi, Stefania; Dennison, Elaine; Al-Daghri, Nasser M; Allepaerts, Sophie; Bauer, Jurgen; Bautmans, Ivan; Brandi, Maria Luisa; Bruyère, Olivier; Cederholm, Tommy; Cerreta, Francesca; Cherubini, Antonio; Cooper, Cyrus; Cruz-Jentoft, Alphonso; McCloskey, Eugene; Dawson-Hughes, Bess; Kaufman, Jean-Marc; Laslop, Andrea; Petermans, Jean; Reginster, Jean-Yves; Rizzoli, René; Robinson, Sian; Rolland, Yves; Rueda, Ricardo; Vellas, Bruno; Kanis, John A
2018-04-01
All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the best technique for measuring lean body mass. Thus, the objective measurement of sarcopenia is hampered by limitations intrinsic to assessment tools. The aim of this study was to review the methods to assess muscle mass and to reach consensus on the development of a reference standard. Literature reviews were performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis working group on frailty and sarcopenia. Face-to-face meetings were organized for the whole group to make amendments and discuss further recommendations. A wide range of techniques can be used to assess muscle mass. Cost, availability, and ease of use can determine whether the techniques are better suited to clinical practice or are more useful for research. No one technique subserves all requirements but dual energy X-ray absorptiometry could be considered as a reference standard (but not a gold standard) for measuring muscle lean body mass. Based on the feasibility, accuracy, safety, and low cost, dual energy X-ray absorptiometry can be considered as the reference standard for measuring muscle mass. © 2018 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders.
NASA Astrophysics Data System (ADS)
Odeyemi, Kehinde O.; Owolawi, Pius A.; Srivastava, Viranjay M.
2017-11-01
Dual-hops transmission is a growing interest technique that can be used to mitigate against atmospheric turbulence along the Free Space Optical (FSO) communication links. This paper analyzes the performance of Decode-and-Forward (DF) dual-hops FSO systems in-conjunction with spatial modulation and diversity combiners over a Gamma-Gamma atmospheric turbulence channel using heterodyne detection. Maximum Ratio Combiner (MRC), Equal Gain Combiner (EGC) and Selection Combiner (SC) are considered at the relay and destination as mitigation tools to improve the system error performance. Power series expansion of modified Bessel function is used to derive the closed form expression for the end-to-end Average Pairwise Error Probability (APEP) expressions for each of the combiners under study and a tight upper bound on the Average Bit Error Rate (ABER) per hop is given. Thus, the overall end-to-end ABER for the dual-hops FSO system is then evaluated. The numerical results depicted that dual-hops transmission systems outperformed the direct link systems. Moreover, the impact of having the same and different combiners at the relay and destination are also presented. The results also confirm that the combination of dual hops transmission with spatial modulation and diversity combiner significantly improves the systems error rate with the MRC combiner offering an optimal performance with respect to variation in atmospheric turbulence, change in links average received SNR and link range of the system.
DOT National Transportation Integrated Search
1973-12-01
Various forms of Dual Mode Transportation were analyzed in order to assess the economic viability of the Dual Mode concept. A Dual Mode vehicle is one which operates under manual control on a streee network for some portionof its trip, and operates u...
Tjalma, Wiebren A A
2017-03-01
Cervical cancer screening saves lives. Secondary prevention in cervical cancer screening relies on the results of primary cytology and/or HPV testing. However, primary screening with cytology has a low sensitivity, and HPV screening has a low specificity. This means that either cancers are missed, or women are over-treated. To improve performance outcomes, the concept of dual-stain cytology (CINtec ® PLUS Cytology test) has been introduced. In this approach, additional staining with p16/Ki-67 is performed in cases where cytology results are abnormal (LSIL or ASCUS) and/or HPV-positive. Another way to describe this approach might be "diagnostic" cytology. In order to assess the value of this "diagnostic cytology", a systematic literature review was conducted of dual-stain cytology performance across multiple studies until May 2016. In a Belgian screening population (women age 25-65 years), dual-stain cytology was significantly more sensitive (66%) and slightly less specific (-1.0%) than cytology. In the population referred to colposcopy or with abnormal cytology (ASCUS, LSIL), dual-staining showed a significantly higher increase in specificity, and a slightly lower sensitivity than HPV testing. Specificity gains resulted in fewer false positives and an increase in the number of correct referrals to colposcopy. Dual-staining with p16/Ki-67 cytology is an attractive biomarker approach for triage in cervical cancer screening. Copyright © 2017 Elsevier B.V. All rights reserved.
Dual delivery of biological therapeutics for multimodal and synergistic cancer therapies.
Jang, Bora; Kwon, Hyokyoung; Katila, Pramila; Lee, Seung Jin; Lee, Hyukjin
2016-03-01
Cancer causes >8.2 million deaths annually worldwide; thus, various cancer treatments have been investigated over the past decades. Among them, combination drug therapy has become extremely popular, and treatment with more than one drug is often necessary to achieve appropriate anticancer efficacy. With the development of nanoformulations and nanoparticulate-based drug delivery, researchers have explored the feasibility of dual delivery of biological therapeutics to overcome the current drawbacks of cancer therapy. Compared with the conventional single drug therapy, dual delivery of therapeutics has provided various synergistic effects in addition to offering multimodality to cancer treatment. In this review, we highlight and summarize three aspects of dual-delivery systems for cancer therapy. These include (1) overcoming drug resistance by the dual delivery of chemical drugs with biological therapeutics for synergistic therapy, (2) targeted and controlled drug release by the dual delivery of drugs with stimuli-responsive nanomaterials, and (3) multimodal theranostics by the dual delivery of drugs and molecular imaging probes. Furthermore, recent developments, perspectives, and new challenges regarding dual-delivery systems for cancer therapy are discussed. Copyright © 2015 Elsevier B.V. All rights reserved.
Dual-mode capability for hardware-in-the-loop
NASA Astrophysics Data System (ADS)
Vamivakas, A. N.; Jackson, Ron L.
2000-07-01
This paper details a Hardware-in-the-Loop Facility (HIL) developed for evaluation and verification of a missile system with dual mode capability. The missile has the capability of tracking and intercepting a target using either an RF antenna or an IR sensor. The testing of a dual mode system presents a significant challenge in the development of the HIL facility. An IR and RF target environment must be presented simultaneously to the missile under test. These targets, simulated by IR and RF sources, must be presented to the missile under test without interference from each other. The location of each source is critical in the development of the HIL facility. The requirements for building a HIL facility with dual mode capability and the methodology for testing the dual mode system are defined within this paper. Methods for the verification and validation of the facility are discussed.
Study of removal of ammonia from urine vapor by dual catalyst
NASA Technical Reports Server (NTRS)
Budininkas, P.
1976-01-01
The feasibility of ammonia removal from urine vapor by a low temperature dual-catalyst system was investigated. The process is based on the initial catalytic oxidation of ammonia present in urine vapor to nitrogen and nitrous oxide, followed by a catalytic decomposition of the nitrous oxide formed into its elements. The most active catalysts for the oxidation of ammonia and for the decomposition of N2O, identified in screening tests, were then combined into dual catalyst systems and tested to establish their overall efficiencies for the removal of ammonia from artificial gas mixtures. Dual catalyst systems capable of ammonia removal from the artificial gas mixtures were then tested with the actual urine vapor produced by boiling untreated urine. A suitable dual catalyst bed arrangement was found that achieved the removal of ammonia and organic carbon, and recovered water of good quality from urine vapor.
A dual-systems perspective on addiction: contributions from neuroimaging and cognitive training.
McClure, Samuel M; Bickel, Warren K
2014-10-01
Dual-systems theories explain lapses in self-control in terms of a conflict between automatic and deliberative modes of behavioral control. Numerous studies have now tested whether the brain areas that control behavior are organized in a manner consistent with dual-systems models. Brain regions directly associated with the mesolimbic dopamine system, the nucleus accumbens and ventromedial prefrontal cortex in particular, capture some of the features assumed by automatic processing. Regions in the lateral prefrontal cortex are more closely linked to deliberative processing and the exertion of self-control in the suppression of impulses. While identifying these regions crudely supports dual-systems theories, important modifications to what constitutes automatic and deliberative behavioral control are also suggested. Experiments have identified various means by which automatic processes may be sculpted. Additional work decomposes deliberative processes into component functions such as generalized working memory, reappraisal of emotional stimuli, and prospection. The importance of deconstructing dual-systems models into specific cognitive processes is clear for understanding and treating addiction. We discuss intervention possibilities suggested by recent research, and focus in particular on cognitive training approaches to bolster deliberative control processes that may aid quit attempts. © 2014 New York Academy of Sciences.
A dual-systems perspective on addiction: contributions from neuroimaging and cognitive training
McClure, Samuel M.; Bickel, Warren K.
2014-01-01
Dual-systems theories explain lapses in self-control in terms of a conflict between automatic and deliberative modes of behavioral control. Numerous studies have now tested whether the brain areas that control behavior are organized in a manner consistent with dual-systems models. Brain regions directly associated with the mesolimbic dopamine system, the nucleus accumbens (NAcc) and ventromedial prefrontal cortex (vmPFC) in particular, capture some of the features assumed by automatic processing. Regions in the lateral prefrontal cortex (lPFC) are more closely linked to deliberative processing and the exertion of self-control in the suppression of impulses. While identifying these regions crudely supports dual-system theories, important modifications to what constitutes automatic and deliberative behavioral control are also suggested. Experiments have identified various means by which automatic processes may be sculpted. Additional work decomposes deliberative processes into component functions such as generalized working memory, reappraisal of emotional stimuli, and prospection. The importance of deconstructing dual-systems models into specific cognitive processes is clear for understanding and treating addiction. We discuss intervention possibilities suggested by recent research, and focus in particular on cognitive training approaches to bolster deliberative control processes that may aid quit attempts. PMID:25336389
Solar Power Satellite (SPS) fiber optic link assessment
NASA Technical Reports Server (NTRS)
1980-01-01
A feasibility demonstration of a 980 MHz fiber optic link for the Solar Power Satellite (SPS) phase reference distribution system was accomplished. A dual fiber-optic link suitable for a phase distribution frequency of 980 MHz was built and tested. The major link components include single mode injection laser diodes, avalanche photodiodes, and multimode high bandwidth fibers. Signal throughput was demonstrated to be stable and of high quality in all cases. For a typical SPS link length of 200 meters, the transmitted phase at 980 MHz varies approximately 2.5 degrees for every deg C of fiber temperature change. This rate is acceptable because of the link length compensation feature of the phase control design.
Jang, Yongwon; Noh, Hyung Wook; Lee, I B; Jung, Ji-Wook; Song, Yoonseon; Lee, Sooyeul; Kim, Seunghwan
2012-01-01
A patch type embedded cardiac function monitoring system was developed to detect arrhythmias such as PVC (Premature Ventricular Contraction), pause, ventricular fibrillation, and tachy/bradycardia. The overall system is composed of a main module including a dual processor and a Bluetooth telecommunication module. The dual microprocessor strategy minimizes power consumption and size, and guarantees the resources of embedded software programs. The developed software was verified with standard DB, and showed good performance.
NASA Technical Reports Server (NTRS)
Obrien, C. J.
1982-01-01
Dual-nozzle engines, such as the dual-throat and dual-expander engines, are being evaluated for advanced earth-to-orbit transportation systems. Potential derivatives of the Space Shuttle and completely new vehicles might benefit from these advanced engines. In this paper, progress in the design of single-fuel and dual-fuel dual-nozzle engines is summarized. Dual-nozzle engines include those burning propellants such as LOX/RP-1/LH2, LOX/LC3H8/LH2, LOX/LCH4/LH2, LOX/LH2/LH2, LOX/LCH4/LCH4, LOX/LC3H8/C3H8 and N2O4/MMH/LH2. Engine data are applicable for thrust levels from 200,000 through 670,000 lbF. The results indicate that several versions of these engines utilize state-of-the-art technology and that even advanced versions of these engines do not require a major breakthrough in technology.
Hussain, Tarique; Mathur, Sujeev; Peel, Sarah A; Valverde, Israel; Bilska, Karolina; Henningsson, Markus; Botnar, Rene M; Simpson, John; Greil, Gerald F
2015-10-27
The purpose of this study was to see how coronary magnetic resonance angiography (CMRA) compared to echocardiography for the detection of coronary artery origins and to compare CMRA measurements for coronary dimensions in children with published echocardiographic reference values. Enrolled patients underwent dual cardiac phase CMRA and echocardiography under the same anesthetic. Echocardiographic measurements of the right coronary artery (RCA), left anterior descending (LAD) and left main (LM) were made. CMRA dimensions were assessed manually at the same points as the echocardiographic measurements. The number of proximal LAD branches imaged was also recorded in order to give an estimate of distal coronary tree visualization. Fifty patients (24 boys, mean age 4.0 years (range 18 days to 18 years)) underwent dual-phase CMRA. Coronary origins were identified in 47/50 cases for CMRA (remaining 3 were infants aged 3, 9 and 11 months). In comparison, origins were identified in 41/50 cases for echo (remaining were all older children). CMRA performed better than echocardiography in terms of distal visualization of the coronary tree (median 1 LAD branch vs. median 0; p = 0.001). Bland-Altman plots show poor agreement between echocardiography and CMRA for coronary measurements. CMRA measurements did vary according to cardiac phase (systolic mean 1.90, s.d. 0.05 mm vs. diastolic mean 1.84, s.d. 0.05 mm; p = 0.002). Dual-phase CMRA has an excellent (94 %) success rate for the detection of coronary origins in children. Newborn infants remain challenging and echocardiography remains the accepted imaging modality for this age group. Echocardiographic reference ranges are not applicable to CMRA measurements as agreement was poor between modalities. Future coronary reference values, using any imaging modality, should quote the phase in which it was measured.
Dual-Polarization Observations of Slowly Varying Solar Emissions from a Mobile X-Band Radar
Gabella, Marco; Leuenberger, Andreas
2017-01-01
The radio noise that comes from the Sun has been reported in literature as a reference signal to check the quality of dual-polarization weather radar receivers for the S-band and C-band. In most cases, the focus was on relative calibration: horizontal and vertical polarizations were evaluated versus the reference signal mainly in terms of standard deviation of the difference. This means that the investigated radar receivers were able to reproduce the slowly varying component of the microwave signal emitted by the Sun. A novel method, aimed at the absolute calibration of dual-polarization receivers, has recently been presented and applied for the C-band. This method requires the antenna beam axis to be pointed towards the center of the Sun for less than a minute. Standard deviations of the difference as low as 0.1 dB have been found for the Swiss radars. As far as the absolute calibration is concerned, the average differences were of the order of −0.6 dB (after noise subtraction). The method has been implemented on a mobile, X-band radar, and this paper presents the successful results that were obtained during the 2016 field campaign in Payerne (Switzerland). Despite a relatively poor Sun-to-Noise ratio, the “small” (~0.4 dB) amplitude of the slowly varying emission was captured and reproduced; the standard deviation of the difference between the radar and the reference was ~0.2 dB. The absolute calibration of the vertical and horizontal receivers was satisfactory. After the noise subtraction and atmospheric correction a, the mean difference was close to 0 dB. PMID:28531164
Dual-Polarization Observations of Slowly Varying Solar Emissions from a Mobile X-Band Radar.
Gabella, Marco; Leuenberger, Andreas
2017-05-22
The radio noise that comes from the Sun has been reported in literature as a reference signal to check the quality of dual-polarization weather radar receivers for the S-band and C-band. In most cases, the focus was on relative calibration: horizontal and vertical polarizations were evaluated versus the reference signal mainly in terms of standard deviation of the difference. This means that the investigated radar receivers were able to reproduce the slowly varying component of the microwave signal emitted by the Sun. A novel method, aimed at the absolute calibration of dual-polarization receivers, has recently been presented and applied for the C-band. This method requires the antenna beam axis to be pointed towards the center of the Sun for less than a minute. Standard deviations of the difference as low as 0.1 dB have been found for the Swiss radars. As far as the absolute calibration is concerned, the average differences were of the order of -0.6 dB (after noise subtraction). The method has been implemented on a mobile, X-band radar, and this paper presents the successful results that were obtained during the 2016 field campaign in Payerne (Switzerland). Despite a relatively poor Sun-to-Noise ratio, the "small" (~0.4 dB) amplitude of the slowly varying emission was captured and reproduced; the standard deviation of the difference between the radar and the reference was ~0.2 dB. The absolute calibration of the vertical and horizontal receivers was satisfactory. After the noise subtraction and atmospheric correction a, the mean difference was close to 0 dB.
Haderslev, Kent Valentin; Jeppesen, Paller Bekker; Sorensen, Henrik Ancher; Mortensen, Per Brobech; Staun, Michael
2003-07-01
Patients who have undergone resection of the small intestine have lower body weight than do healthy persons. It remains unclear whether it is the body fat mass or the lean tissue mass that is reduced. We compared body-composition values in patients who had undergone small-intestinal resection with reference values obtained in healthy volunteers, and we studied the relation between body-composition estimates and the net intestinal absorption of energy. In a cross-sectional study, we included 20 men and 24 women who had undergone small-intestinal resection and had malabsorption of energy > 2000 kJ/d. Diagnoses were Crohn disease (n = 37) and other conditions (n = 7). Body composition was estimated by dual-energy X-ray absorptiometry, and data were compared with those from a reference group of 173 healthy volunteers. Energy absorption was measured during 48-h balance studies by using bomb calorimetry, and individual values were expressed relative to the basal metabolic rate. Body weight and body mass index in patients were significantly (P < 0.05) lower than the reference values. Fat mass was 6.4 kg (30%) lower (95% CI: -8.8, -3.9 kg), but lean tissue mass was only slightly and insignificantly lower (1.5 kg, or 3.3%; 95% CI: -3.7, 0.60 kg). Weight, body mass index, and body-composition estimates by dual-energy X-ray absorptiometry did not correlate significantly with the net energy absorption relative to the basal metabolic rate, expressed as a percentage. Patients who had undergone small-intestinal resection had significantly lower body weights and body mass indexes than did healthy persons, and they had significant changes in body composition, mainly decreased body fat mass.
Bone images from dual-energy subtraction chest radiography in the detection of rib fractures.
Szucs-Farkas, Zsolt; Lautenschlager, Katrin; Flach, Patricia M; Ott, Daniel; Strautz, Tamara; Vock, Peter; Ruder, Thomas D
2011-08-01
To assess the sensitivity and image quality of chest radiography (CXR) with or without dual-energy subtracted (ES) bone images in the detection of rib fractures. In this retrospective study, 39 patients with 204 rib fractures and 24 subjects with no fractures were examined with a single exposure dual-energy subtraction digital radiography system. Three blinded readers first evaluated the non-subtracted posteroanterior and lateral chest radiographs alone, and 3 months later they evaluated the non-subtracted images together with the subtracted posteroanterior bone images. The locations of rib fractures were registered with confidence levels on a 3-grade scale. Image quality was rated on a 5-point scale. Marks by readers were compared with fracture localizations in CT as a standard of reference. The sensivity for fracture detection using both methods was very similar (34.3% with standard CXR and 33.5% with ES-CXR, p=0.92). At the patient level, both sensitivity (71.8%) and specificity (92.9%) with or without ES were identical. Diagnostic confidence was not significantly different (2.61 with CXR and 2.75 with ES-CXR, p=0.063). Image quality with ES was rated higher than that on standard CXR (4.08 vs. 3.74, p<0.001). Despite a better image quality, adding ES bone images to standard radiographs of the chest does not provide better sensitivity or improved diagnostic confidence in the detection of rib fractures. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shiinoki, T; Shibuya, K; Sawada, A
Purpose: The new real-time tumor-tracking radiotherapy (RTRT) system was installed in our institution. This system consists of two x-ray tubes and color image intensifiers (I.I.s). The fiducial marker which was implanted near the tumor was tracked using color fluoroscopic images. However, the implantation of the fiducial marker is very invasive. Color fluoroscopic images enable to increase the recognition of the tumor. However, these images were not suitable to track the tumor without fiducial marker. The purpose of this study was to investigate the feasibility of markerless tracking using dual energy colored fluoroscopic images for real-time tumor-tracking radiotherapy system. Methods: Themore » colored fluoroscopic images of static and moving phantom that had the simulated tumor (30 mm diameter sphere) were experimentally acquired using the RTRT system. The programmable respiratory motion phantom was driven using the sinusoidal pattern in cranio-caudal direction (Amplitude: 20 mm, Time: 4 s). The x-ray condition was set to 55 kV, 50 mA and 105 kV, 50 mA for low energy and high energy, respectively. Dual energy images were calculated based on the weighted logarithmic subtraction of high and low energy images of RGB images. The usefulness of dual energy imaging for real-time tracking with an automated template image matching algorithm was investigated. Results: Our proposed dual energy subtraction improve the contrast between tumor and background to suppress the bone structure. For static phantom, our results showed that high tracking accuracy using dual energy subtraction images. For moving phantom, our results showed that good tracking accuracy using dual energy subtraction images. However, tracking accuracy was dependent on tumor position, tumor size and x-ray conditions. Conclusion: We indicated that feasibility of markerless tracking using dual energy fluoroscopic images for real-time tumor-tracking radiotherapy system. Furthermore, it is needed to investigate the tracking accuracy using proposed dual energy subtraction images for clinical cases.« less
Information of Complex Systems and Applications in Agent Based Modeling.
Bao, Lei; Fritchman, Joseph C
2018-04-18
Information about a system's internal interactions is important to modeling the system's dynamics. This study examines the finer categories of the information definition and explores the features of a type of local information that describes the internal interactions of a system. Based on the results, a dual-space agent and information modeling framework (AIM) is developed by explicitly distinguishing an information space from the material space. The two spaces can evolve both independently and interactively. The dual-space framework can provide new analytic methods for agent based models (ABMs). Three examples are presented including money distribution, individual's economic evolution, and artificial stock market. The results are analyzed in the dual-space, which more clearly shows the interactions and evolutions within and between the information and material spaces. The outcomes demonstrate the wide-ranging applicability of using the dual-space AIMs to model and analyze a broad range of interactive and intelligent systems.
Kang, Bo-Kyeong; Yu, Eun Sil; Lee, Seung Soo; Lee, Youngjoo; Kim, Namkug; Sirlin, Claude B; Cho, Eun Yoon; Yeom, Suk Keu; Byun, Jae Ho; Park, Seong Ho; Lee, Moon-Gyu
2012-06-01
The aims of this study were to assess the confounding effects of hepatic iron deposition, inflammation, and fibrosis on hepatic steatosis (HS) evaluation by magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) and to assess the accuracies of MRI and MRS for HS evaluation, using histology as the reference standard. In this institutional review board-approved prospective study, 56 patients gave informed consents and underwent chemical-shift MRI and MRS of the liver on a 1.5-T magnetic resonance scanner. To estimate MRI fat fraction (FF), 4 analysis methods were used (dual-echo, triple-echo, multiecho, and multi-interference), and MRS FF was calculated with T2 correction. Degrees of HS, iron deposition, inflammation, and fibrosis were analyzed in liver resection (n = 37) and biopsy (n = 19) specimens. The confounding effects of histology on fat quantification were assessed by multiple linear regression analysis. Using the histologic degree of HS as the reference standard, the accuracies of each method in estimating HS and diagnosing an HS of 5% or greater were determined by linear regression and receiver operating characteristic analyses. Iron deposition significantly confounded estimations of FF by the dual-echo (P < 0.001) and triple-echo (P = 0.033) methods, whereas no histologic feature confounded the multiecho and multi-interference methods or MRS. The MRS (r = 0.95) showed the strongest correlation with histologic degree of HS, followed by the multiecho (r = 0.92), multi-interference (r = 0.91), triple-echo (r = 0.90), and dual-echo (r = 0.85) methods. For diagnosing HS, the areas under the curve tended to be higher for MRS (0.96) and the multiecho (0.95), multi-interference (0.95), and triple-echo (0.95) methods than for the dual-echo method (0.88) (P ≥ 0.13). The multiecho and multi-interference MRI methods and MRS can accurately quantify hepatic fat, with coexisting histologic abnormalities having no confounding effects.
Dual chain perturbation theory: A new equation of state for polyatomic molecules
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marshall, Bennett D., E-mail: bennett.d.marshall@exxonmobil.com
In the development of equations of state for polyatomic molecules, thermodynamic perturbation theory (TPT) is widely used to calculate the change in free energy due to chain formation. TPT is a simplification of a more general and exact multi-density cluster expansion for associating fluids. In TPT, all contributions to the cluster expansion which contain chain–chain interactions are neglected. That is, all inter-chain interactions are treated at the reference fluid level. This allows for the summation of the cluster theory in terms of reference system correlation functions only. The resulting theory has been shown to be accurate and has been widelymore » employed as the basis of many engineering equations of state. While highly successful, TPT has many handicaps which result from the neglect of chain–chain contributions. The subject of this document is to move beyond the limitations of TPT and include chain–chain contributions to the equation of state.« less
Higher-order ionospheric error at Arecibo, Millstone, and Jicamarca
NASA Astrophysics Data System (ADS)
Matteo, N. A.; Morton, Y. T.
2010-12-01
The ionosphere is a dominant source of Global Positioning System receiver range measurement error. Although dual-frequency receivers can eliminate the first-order ionospheric error, most second- and third-order errors remain in the range measurements. Higher-order ionospheric error is a function of both electron density distribution and the magnetic field vector along the GPS signal propagation path. This paper expands previous efforts by combining incoherent scatter radar (ISR) electron density measurements, the International Reference Ionosphere model, exponential decay extensions of electron densities, the International Geomagnetic Reference Field, and total electron content maps to compute higher-order error at ISRs in Arecibo, Puerto Rico; Jicamarca, Peru; and Millstone Hill, Massachusetts. Diurnal patterns, dependency on signal direction, seasonal variation, and geomagnetic activity dependency are analyzed. Higher-order error is largest at Arecibo with code phase maxima circa 7 cm for low-elevation southern signals. The maximum variation of the error over all angles of arrival is circa 8 cm.
Vaezghasemi, Masoud; Öhman, Ann; Eriksson, Malin; Hakimi, Mohammad; Weinehall, Lars; Kusnanto, Hari; Ng, Nawi
2014-01-01
Introduction The paradoxical phenomenon of the coexistence of overweight and underweight individuals in the same household, referred to as the “dual burden of malnutrition”, is a growing nutrition dilemma in low- and middle-income countries (LMICs). Aims The objectives of this study were (i) to examine the extent of the dual burden of malnutrition across different provinces in Indonesia and (ii) to determine how gender, community social capital, place of residency and other socio-economic factors affect the prevalence of the dual burden of malnutrition. Methods The current study utilized data from the fourth wave of the Indonesian Family Life Survey (IFLS) conducted between November 2007 and April 2008. The dataset contains information from 12,048 households and 45,306 individuals of all ages. This study focused on households with individuals over two years old. To account for the multilevel nature of the data, a multilevel multiple logistic regression was conducted. Results Approximately one-fifth of all households in Indonesia exhibited the dual burden of malnutrition, which was more prevalent among male-headed households, households with a high Socio-economic status (SES), and households in urban areas. Minimal variation in the dual burden of malnutrition was explained by the community level differences (<4%). Living in households with a higher SES resulted in higher odds of the dual burden of malnutrition but not among female-headed households and communities with the highest social capital. Conclusion To improve household health and reduce the inequality across different SES groups, this study emphasizes the inclusion of women's empowerment and community social capital into intervention programs addressing the dual burden of malnutrition. PMID:25153321
Design integration for minimal energy and cost
DOE Office of Scientific and Technical Information (OSTI.GOV)
Halldane, J.E.
The authors present requirements for creating alternative energy conserving designs including energy management and architectural, plumbing, mechanical, electrical, electronic and optical design. Parameters of power, energy, life cycle costs and benefit for resource for an evaluation by the interested parties are discussed. They present an analysis of power systems through a seasonal power distribution diagram. An analysis of cost systems includes capital cost from the power components, annual costs from the utility energy use, and finance costs with loans, taxes, settlement and design fees. Equations are transposed to the evaluative parameter and are uniquely explicit with consistent symbols, parameter definitions,more » dual and balanced units, unit conversions, criteria for operation, incorporated constants for rapid calculations, references to data in the handbook, other common terms, and instrumentation for the measurement. Each component equation has a key power diagram.« less
Kalkwarf, Heidi J.; Gilsanz, Vicente; Lappe, Joan M.; Oberfield, Sharon; Shepherd, John A.; Frederick, Margaret M.; Huang, Xiangke; Lu, Ming; Mahboubi, Soroosh; Hangartner, Thomas; Winer, Karen K.
2011-01-01
Context: Deficits in bone acquisition during growth may increase fracture risk. Assessment of bone health during childhood requires appropriate reference values relative to age, sex, and population ancestry to identify bone deficits. Objective: The objective of this study was to provide revised and extended reference curves for bone mineral content (BMC) and areal bone mineral density (aBMD) in children. Design: The Bone Mineral Density in Childhood Study was a multicenter longitudinal study with annual assessments for up to 7 yr. Setting: The study was conducted at five clinical centers in the United States. Participants: Two thousand fourteen healthy children (992 males, 22% African-Americans) aged 5–23 yr participated in the study. Intervention: There were no interventions. Main Outcome Measures: Reference percentiles for BMC and aBMD of the total body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry for Black and non-Black children. Adjustment factors for height status were also calculated. Results: Extended reference curves for BMC and aBMD of the total body, total body less head, lumbar spine, total hip, femoral neck, and forearm for ages 5–20 yr were constructed relative to sex and age for Black and non-Black children. Curves are similar to those previously published for 7–17 year olds. BMC and aBMD values were greater for Black vs. non-Black children at all measurement sites. Conclusions: We provide here dual-energy x-ray absorptiometry reference data on a well-characterized cohort of 2012 children and adolescents. These reference curves provide the most robust reference values for the assessment and monitoring of bone health in children and adolescents in the literature to date. PMID:21917867
Comerford, Julia M.; Pooley, David; Barrows, R. Scott; ...
2015-06-19
Dual active galactic nuclei (AGNs) and offset AGNs are kpc-scale separation supermassive black holes pairs created during galaxy mergers, where both or one of the black holes are AGNs, respectively. These dual and offset AGNs are valuable probes of the link between mergers and AGNs but are challenging to identify. Here we present Chandra/ACIS observations of 12 optically selected dual AGN candidates atmore » $$z\\lt 0.34$$, where we use the X-rays to identify AGNs. We also present Hubble Space Telescope/Wide Field Camera 3 observations of 10 of these candidates, which reveal any stellar bulges accompanying the AGNs. We discover a dual AGN system with separation $${\\rm \\Delta }x=2.2$$ kpc, where the two stellar bulges have coincident [O iii] λ5007 and X-ray sources. This system is an extremely minor merger (460:1) that may include a dwarf galaxy hosting an intermediate mass black hole. We also find six single AGNs, and five systems that are either dual or offset AGNs with separations $${\\rm \\Delta }x\\lt 10$$ kpc. Four of the six dual AGNs and dual/offset AGNs are in ongoing major mergers, and these AGNs are 10 times more luminous, on average, than the single AGNs in our sample. This hints that major mergers may preferentially trigger higher luminosity AGNs. Further, we find that confirmed dual AGNs have hard X-ray luminosities that are half of those of single AGNs at fixed [O III] λ5007 luminosity, on average. Lastly, this could be explained by high densities of gas funneled to galaxy centers during mergers, and emphasizes the need for deeper X-ray observations of dual AGN candidates.« less
Srivastava, Abneesh; Michael Verkouteren, R
2018-07-01
Isotope ratio measurements have been conducted on a series of isotopically distinct pure CO 2 gas samples using the technique of dual-inlet isotope ratio mass spectrometry (DI-IRMS). The influence of instrumental parameters, data normalization schemes on the metrological traceability and uncertainty of the sample isotope composition have been characterized. Traceability to the Vienna PeeDee Belemnite(VPDB)-CO 2 scale was realized using the pure CO 2 isotope reference materials(IRMs) 8562, 8563, and 8564. The uncertainty analyses include contributions associated with the values of iRMs and the repeatability and reproducibility of our measurements. Our DI-IRMS measurement system is demonstrated to have high long-term stability, approaching a precision of 0.001 parts-per-thousand for the 45/44 and 46/44 ion signal ratios. The single- and two-point normalization bias for the iRMs were found to be within their published standard uncertainty values. The values of 13 C/ 12 C and 18 O/ 16 O isotope ratios are expressed relative to VPDB-CO 2 using the [Formula: see text] and [Formula: see text] notation, respectively, in parts-per-thousand (‰ or per mil). For the samples, value assignments between (-25 to +2) ‰ and (-33 to -1) ‰ with nominal combined standard uncertainties of (0.05, 0.3) ‰ for [Formula: see text] and [Formula: see text], respectively were obtained. These samples are used as laboratory reference to provide anchor points for value assignment of isotope ratios (with VPDB traceability) to pure CO 2 samples. Additionally, they serve as potential parent isotopic source material required for the development of gravimetric based iRMs of CO 2 in CO 2 -free dry air in high pressure gas cylinder packages at desired abundance levels and isotopic composition values. Graphical abstract CO 2 gas isotope ratio metrology.
Image quality and absorbed dose comparison of single- and dual-source cone-beam computed tomography.
Miura, Hideharu; Ozawa, Shuichi; Okazue, Toshiya; Kawakubo, Atsushi; Yamada, Kiyoshi; Nagata, Yasushi
2018-05-01
Dual-source cone-beam computed tomography (DCBCT) is currently available in the Vero4DRT image-guided radiotherapy system. We evaluated the image quality and absorbed dose for DCBCT and compared the values with those for single-source CBCT (SCBCT). Image uniformity, Hounsfield unit (HU) linearity, image contrast, and spatial resolution were evaluated using a Catphan phantom. The rotation angle for acquiring SCBCT and DCBCT images is 215° and 115°, respectively. The image uniformity was calculated using measurements obtained at the center and four peripheral positions. The HUs of seven materials inserted into the phantom were measured to evaluate HU linearity and image contrast. The Catphan phantom was scanned with a conventional CT scanner to measure the reference HU for each material. The spatial resolution was calculated using high-resolution pattern modules. Image quality was analyzed using ImageJ software ver. 1.49. The absorbed dose was measured using a 0.6-cm 3 ionization chamber with a 16-cm-diameter cylindrical phantom, at the center and four peripheral positions of the phantom, and calculated using weighted cone-beam CT dose index (CBCTDI w ). Compared with that of SCBCT, the image uniformity of DCBCT was slightly reduced. A strong linear correlation existed between the measured HU for DCBCT and the reference HU, although the linear regression slope was different from that of the reference HU. DCBCT had poorer image contrast than did SCBCT, particularly with a high-contrast material. There was no significant difference between the spatial resolutions of SCBCT and DCBCT. The absorbed dose for DCBCT was higher than that for SCBCT, because in DCBCT, the two x-ray projections overlap between 45° and 70°. We found that the image quality was poorer and the absorbed dose was higher for DCBCT than for SCBCT in the Vero4DRT. © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.
Imboden, Mary T; Swartz, Ann M; Finch, Holmes W; Harber, Matthew P; Kaminsky, Leonard A
2017-01-01
To develop reference values by age and sex for LM measures using GE-Healthcare DXA systems. A de-identified sample was obtained from Ball State University's Clinical Exercise Physiology Laboratory and University of Wisconsin-Milwaukee's Physical Activity & Health Research Laboratory. DXA scans of 2,076 women and 1,251 men were completed using a GE Lunar Prodigy or iDXA. Percentiles (%ile) were calculated for all variables of interest (LM, LMI, %LM, and ALMI) and a factorial ANOVA was used to assess differences for each variable between 10-year age groups and sex, as well as the interaction between age and sex. Men had higher mean total LM, %LM, LMI, and ALMI than women (p<0.01), across all age groups. All LM variables decreased significantly over the 5 decades in men, however in women only total LM, %LM, and ALMI decreased from the youngest to oldest age groups (p<0.01). These reference values provide for a more accurate interpretation of GE-Healthcare DXA-derived LM measurements offering clinicians and researchers with an initial resource to aid in the early detection and assessment of LM deficits.
Management and Leadership: A Dual Role in Nursing Education.
ERIC Educational Resources Information Center
Calpin-Davies, Philomena J.
2003-01-01
Caring is the end purpose of nursing. The management and leadership of education for empowered caring requires teaching and learning that develop creative, flexible, interdependent nurses. Key issues are investing in technology, supporting lifelong learning, and creating a community workplace. (Contains 68 references.) (SK)
Hypermedia Concepts and Research: An Overview.
ERIC Educational Resources Information Center
Burton, John K.; And Others
1995-01-01
Provides an overview of hypermedia, including a history of hypertext and multimedia, and discusses how they have been combined into the term hypermedia; a cognitive overview; dual coding and cue summation; and theories related to learners, including field dependence-independence, memory, and metacognition. Contains 156 references. (LRW)
How Geographic Maps Increase Recall of Instructional Text.
ERIC Educational Resources Information Center
Kulhavy, Raymond W.; And Others
1993-01-01
Reviews research on how geographic maps influence the recall of associated text and describes a theoretical model of map-text learning based on dual-coding theory and working memory operations. Instructional implications are explained, and recommendations for instructional applications are given. (Contains 84 references.) (LRW)
NASA Astrophysics Data System (ADS)
Hennig, Georg; Vogeser, Michael; Holdt, Lesca M.; Homann, Christian; Großmann, Michael; Stepp, Herbert; Gruber, Christian; Erdogan, Ilknur; Hasmüller, Stephan; Hasbargen, Uwe; Brittenham, Gary M.
2014-02-01
Erythrocyte zinc protoporphyrin-IX (ZnPP) and protoporphyrin-IX (PPIX) accumulate in a variety of disorders that restrict or disrupt the biosynthesis of heme, including iron deficiency and various porphyrias. We describe a reagent-free spectroscopic method based on dual-wavelength excitation that can measure simultaneously both ZnPP and PPIX fluorescence from unwashed whole blood while virtually eliminating background fluorescence. We further aim to quantify ZnPP and PPIX non-invasively from the intact oral mucosa using dual-wavelength excitation to reduce the strong tissue background fluorescence while retaining the faint porphyrin fluorescence signal originating from erythrocytes. Fluorescence spectroscopic measurements were made on 35 diluted EDTA blood samples using a custom front-face fluorometer. The difference spectrum between fluorescence at 425 nm and 407 nm excitation effectively eliminated background autofluorescence while retaining the characteristic porphyrin peaks. These peaks were evaluated quantitatively and the results compared to a reference HPLC-kit method. A modified instrument using a single 1000 μm fiber for light delivery and detection was used to record fluorescence spectra from oral mucosa. For blood measurements, the ZnPP and PPIX fluorescence intensities from the difference spectra correlated well with the reference method (ZnPP: Spearman's rho rs = 0.943, p < 0.0001; PPIX: rs = 0.959, p < 0.0001). In difference spectra from oral mucosa, background fluorescence was reduced significantly, while porphyrin signals remained observable. The dual-wavelength excitation method evaluates quantitatively the ZnPP/heme and PPIX/heme ratios from unwashed whole blood, simplifying clinical laboratory measurements. The difference technique reduces the background fluorescence from measurements on oral mucosa, allowing for future non-invasive quantitation of erythrocyte ZnPP and PPIX.
A high-precision, distributed geodetic strainmeter based on dual coaxial cable Bragg gratings
NASA Astrophysics Data System (ADS)
Fu, J.; Wei, T.; Wei, M.; Shen, Y.
2014-12-01
Observations of surface deformation are essential for understanding a wide range of geophysical problems, including earthquakes, volcanoes, landslides, and glaciers. Current geodetic technologies, such as GPS, InSAR, borehole and laser strainmeters, are costly and limited in their temporal or spatial resolution. Here we present a new type of strainmeter based on coaxial cable Bragg grating (CCBG) sensing technology that provides high-precision, distributed strain measurements at a moderate cost. The coaxial-cable-based strainmeter is designed to cover a long distance (~ km) under harsh environmental conditions such as extreme temperatures. To minimize the environmental noises, two CCBGs are introduced into the geodetic strainmeter: one is used to measure the strain applied on it, and the other acts as a reference only to detect the environmental noises. The environmental noises are removed using the inputs from the strained CCBG and the reference CCBG in a frequency mixer. The test results show that the geodetic strainmeter with dual CCBGs has micron-strain accuracy in the lab.
Critical Analysis of Dual-Probe Heat-Pulse Technique Applied to Measuring Thermal Diffusivity
NASA Astrophysics Data System (ADS)
Bovesecchi, G.; Coppa, P.; Corasaniti, S.; Potenza, M.
2018-07-01
The paper presents an analysis of the experimental parameters involved in application of the dual-probe heat pulse technique, followed by a critical review of methods for processing thermal response data (e.g., maximum detection and nonlinear least square regression) and the consequent obtainable uncertainty. Glycerol was selected as testing liquid, and its thermal diffusivity was evaluated over the temperature range from - 20 °C to 60 °C. In addition, Monte Carlo simulation was used to assess the uncertainty propagation for maximum detection. It was concluded that maximum detection approach to process thermal response data gives the closest results to the reference data inasmuch nonlinear regression results are affected by major uncertainties due to partial correlation between the evaluated parameters. Besides, the interpolation of temperature data with a polynomial to find the maximum leads to a systematic difference between measured and reference data, as put into evidence by the Monte Carlo simulations; through its correction, this systematic error can be reduced to a negligible value, about 0.8 %.
On-chip dual-comb source for spectroscopy.
Dutt, Avik; Joshi, Chaitanya; Ji, Xingchen; Cardenas, Jaime; Okawachi, Yoshitomo; Luke, Kevin; Gaeta, Alexander L; Lipson, Michal
2018-03-01
Dual-comb spectroscopy is a powerful technique for real-time, broadband optical sampling of molecular spectra, which requires no moving components. Recent developments with microresonator-based platforms have enabled frequency combs at the chip scale. However, the need to precisely match the resonance wavelengths of distinct high quality-factor microcavities has hindered the development of on-chip dual combs. We report the simultaneous generation of two microresonator combs on the same chip from a single laser, drastically reducing experimental complexity. We demonstrate broadband optical spectra spanning 51 THz and low-noise operation of both combs by deterministically tuning into soliton mode-locked states using integrated microheaters, resulting in narrow (<10 kHz) microwave beat notes. We further use one comb as a reference to probe the formation dynamics of the other comb, thus introducing a technique to investigate comb evolution without auxiliary lasers or microwave oscillators. We demonstrate high signal-to-noise ratio absorption spectroscopy spanning 170 nm using the dual-comb source over a 20-μs acquisition time. Our device paves the way for compact and robust spectrometers at nanosecond time scales enabled by large beat-note spacings (>1 GHz).
Advanced Laser Based Measurements in Porous Media Combustion
NASA Technical Reports Server (NTRS)
Tedder, Sarah A.
2009-01-01
We present measurements using dual-pump dual-broadband coherent anti-Stokes Raman scattering spectroscopy (DP-DBB-CARS) inside a porous media burner. This work continues our previous measurements in such combustion systems. The existing setup was significantly modified with the aim of providing improved data quality and data rate, reduction of interferences and additional species information. These changes are presented and discussed in detail. The CARS technique was expanded to a dual-pump dual-broadband CARS system which in principle enables acquisition of temperatures together with relative H2/N2- and O2/N2- species concentrations. Experimental complexity was reduced by the use of a modified spectrometer enabling the detection of both signals, vibrational and rotational CARS, with only one detection system.
Design of an ultra-thin dual band infrared system
NASA Astrophysics Data System (ADS)
Du, Ke; Cheng, Xuemin; Lv, Qichao; Hu, YiFei
2014-11-01
The ultra-thin imaging system using reflective multiple-fold structure has smaller volume and less weight while maintaining high resolution compared with conventional optical systems. The multi-folded approach can significantly extend focal distance within wide spectral range without incurring chromatic aberrations. In this paper, we present a dual infrared imaging system of four-folded reflection with two air-spaced concentric reflective surfaces. The dual brand IR system has 107mm effective focal length, 0.7NA, +/-4° FOV, and 50mm effective aperture with 80mm outer diameter into a 25mm total thickness, which spectral response is 3~12μm.
NASA Astrophysics Data System (ADS)
Buksa, John J.; Kirk, William L.; Cappiello, Michael W.
A preliminary assessment of the technical feasibility and mass competitiveness of a dual-mode nuclear propulsion and power system based on the NERVA rocket engine has been completed. Results indicate that the coupling of the Rover reactor to a direct Brayton power conversion system can be accomplished through a number of design features. Furthermore, based on previously published and independently calculated component masses, the dual-mode system was found to have the potential to be mass competitive with propulsion/power systems that use separate reactors. The uncertainties of reactor design modification and shielding requirements were identified as important issues requiring future investigation.
Counter sniper: a localization system based on dual thermal imager
NASA Astrophysics Data System (ADS)
He, Yuqing; Liu, Feihu; Wu, Zheng; Jin, Weiqi; Du, Benfang
2010-11-01
Sniper tactics is widely used in modern warfare, which puts forward the urgent requirement of counter sniper detection devices. This paper proposed the anti-sniper detection system based on a dual-thermal imaging system. Combining the infrared characteristics of the muzzle flash and bullet trajectory of binocular infrared images obtained by the dual-infrared imaging system, the exact location of the sniper was analyzed and calculated. This paper mainly focuses on the system design method, which includes the structure and parameter selection. It also analyzes the exact location calculation method based on the binocular stereo vision and image analysis, and give the fusion result as the sniper's position.
Dual linear accelerator system for use in sterilization of medical disposable supplies
NASA Astrophysics Data System (ADS)
Sadat, Theo
1991-05-01
Accelerators can be used for sterilization or decontamination (medical disposables, food, plastics, hospital waste, etc.). Most of these accelerators are located in an industrial environment and must have a high availability. A dual accelerator system (composed of two accelerators) offers optimal flexibility and reliability. The main advantage of this system is "all-in all-out" because it does not need a turnover of products. Such a dual system, composed of two 10 MeV 20 kW linear accelerators (instead of one 40 kW linac), has been chosen by a Swedish company (Mölnlycke).
Robles-Martínez, María; García-Carretero, Miguel Ángel; Gibert, Juan; Palma-Álvarez, Raúl Felipe; Abad, Alfonso Carlos; Sorribes, Marta; Roncero, Carlos
2018-01-23
Dual diagnosis is the coexistence of an addictive disorder and another mental disorder. The objective is to estimate cravings and self-reported quality of life in a sample of patients with alcoholic dependence, with or without dual pathology, who attend an outpatient treatment centre. A cross-sectional study of 112 patients (56 dual and 56 non-dual), diagnosed with alcohol dependence according to DSM-IV-TR. The presence of cravings is determined by the Multidimensional Alcohol Craving Scale and quality of life through the SF-36 Health Questionnaire. There are no statistically significant differences in cravings in either subgroup; the latter tend to refer to lower alcohol cravings than non-dual patients. The dual patients have a worse quality of life in all categories evaluated, highlighting a worse quality of life in the categories: social function, emotional role, vitality and general health. Females present a lower quality of life emphasising those of social function and emotional role. No differences were detected in relation to cravings between the 2 groups. In order to perform a correct clinical and therapeutic approach for patients with alcohol dependence, we should consider focusing on the evaluation of cravings and quality of life. In order to perform a correct clinical and therapeutic approach for patients with alcohol dependence, it is necessary to consider cravings and quality of life, since these parameters are important for the evaluation of patients with alcohol dependence. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.
Safety and Crashworthiness of Dual Mode Vehicles
DOT National Transportation Integrated Search
1974-01-01
Safety features and the degree of safety expected of dual-mode systems are reviewed. Some of the inherent advantages and disadvantages of dual-mode transportation are also outlined. Possible categories of vehicle safety are defined to aid in developi...
Demagnetization monitoring and life extending control for permanent magnet-driven traction systems
NASA Astrophysics Data System (ADS)
Niu, Gang; Liu, Senyi
2018-03-01
This paper presents a novel scheme of demagnetization monitoring and life extending control for traction systems driven by permanent magnet synchronous motors (PMSMs). Firstly, the offline training is carried to evaluate fatigue damage of insulated gate bipolar transistors (IGBTs) under different flux loss based on first-principle modeling. Then an optimal control law can be extracted by turning down the power distribution factor of the demagnetizing PMSM until all damages of IGBTs turn to balance. Next, the similarity-based empirical modeling is employed to online estimate remaining flux of PMSMs, which is used to update the power distribution factor by referring the optimal control law for the health-oriented autonomous control. The proposed strategy can be demonstrated by a case study of traction drive system coupled with dual-PMSMs. Compared with traditional control strategy, the results show that the novel scheme can not only guarantee traction performance but also extend remaining useful life (RUL) of the system after suffering demagnetization fault.
Dual redundant core memory systems
NASA Technical Reports Server (NTRS)
Hull, F. E.
1972-01-01
Electronic memory system consisting of series redundant drive switch circuits, triple redundant majority voted memory timing functions, and two data registers to provide functional dual redundancy is described. Signal flow through the circuits is illustrated and equence of events which occur within the memory system is explained.
NASA Technical Reports Server (NTRS)
Kobayashi, Takahisa; Simon, Donald L.
2008-01-01
In this paper, an enhanced on-line diagnostic system which utilizes dual-channel sensor measurements is developed for the aircraft engine application. The enhanced system is composed of a nonlinear on-board engine model (NOBEM), the hybrid Kalman filter (HKF) algorithm, and fault detection and isolation (FDI) logic. The NOBEM provides the analytical third channel against which the dual-channel measurements are compared. The NOBEM is further utilized as part of the HKF algorithm which estimates measured engine parameters. Engine parameters obtained from the dual-channel measurements, the NOBEM, and the HKF are compared against each other. When the discrepancy among the signals exceeds a tolerance level, the FDI logic determines the cause of discrepancy. Through this approach, the enhanced system achieves the following objectives: 1) anomaly detection, 2) component fault detection, and 3) sensor fault detection and isolation. The performance of the enhanced system is evaluated in a simulation environment using faults in sensors and components, and it is compared to an existing baseline system.
Asymmetric Dual-Band Tracking Technique for Optimal Joint Processing of BDS B1I and B1C Signals
Wang, Chuhan; Cui, Xiaowei; Ma, Tianyi; Lu, Mingquan
2017-01-01
Along with the rapid development of the Global Navigation Satellite System (GNSS), satellite navigation signals have become more diversified, complex, and agile in adapting to increasing market demands. Various techniques have been developed for processing multiple navigation signals to achieve better performance in terms of accuracy, sensitivity, and robustness. This paper focuses on a technique for processing two signals with separate but adjacent center frequencies, such as B1I and B1C signals in the BeiDou global system. The two signals may differ in modulation scheme, power, and initial phase relation and can be processed independently by user receivers; however, the propagation delays of the two signals from a satellite are nearly identical as they are modulated on adjacent frequencies, share the same reference clock, and undergo nearly identical propagation paths to the receiver, resulting in strong coherence between the two signals. Joint processing of these signals can achieve optimal measurement performance due to the increased Gabor bandwidth and power. In this paper, we propose a universal scheme of asymmetric dual-band tracking (ASYM-DBT) to take advantage of the strong coherence, the increased Gabor bandwidth, and power of the two signals in achieving much-reduced thermal noise and more accurate ranging results when compared with the traditional single-band algorithm. PMID:29035350
NASA Astrophysics Data System (ADS)
Jakovetic, Dusan; Xavier, João; Moura, José M. F.
2011-08-01
We study distributed optimization in networked systems, where nodes cooperate to find the optimal quantity of common interest, x=x^\\star. The objective function of the corresponding optimization problem is the sum of private (known only by a node,) convex, nodes' objectives and each node imposes a private convex constraint on the allowed values of x. We solve this problem for generic connected network topologies with asymmetric random link failures with a novel distributed, decentralized algorithm. We refer to this algorithm as AL-G (augmented Lagrangian gossiping,) and to its variants as AL-MG (augmented Lagrangian multi neighbor gossiping) and AL-BG (augmented Lagrangian broadcast gossiping.) The AL-G algorithm is based on the augmented Lagrangian dual function. Dual variables are updated by the standard method of multipliers, at a slow time scale. To update the primal variables, we propose a novel, Gauss-Seidel type, randomized algorithm, at a fast time scale. AL-G uses unidirectional gossip communication, only between immediate neighbors in the network and is resilient to random link failures. For networks with reliable communication (i.e., no failures,) the simplified, AL-BG (augmented Lagrangian broadcast gossiping) algorithm reduces communication, computation and data storage cost. We prove convergence for all proposed algorithms and demonstrate by simulations the effectiveness on two applications: l_1-regularized logistic regression for classification and cooperative spectrum sensing for cognitive radio networks.
Asymmetric Dual-Band Tracking Technique for Optimal Joint Processing of BDS B1I and B1C Signals.
Wang, Chuhan; Cui, Xiaowei; Ma, Tianyi; Zhao, Sihao; Lu, Mingquan
2017-10-16
Along with the rapid development of the Global Navigation Satellite System (GNSS), satellite navigation signals have become more diversified, complex, and agile in adapting to increasing market demands. Various techniques have been developed for processing multiple navigation signals to achieve better performance in terms of accuracy, sensitivity, and robustness. This paper focuses on a technique for processing two signals with separate but adjacent center frequencies, such as B1I and B1C signals in the BeiDou global system. The two signals may differ in modulation scheme, power, and initial phase relation and can be processed independently by user receivers; however, the propagation delays of the two signals from a satellite are nearly identical as they are modulated on adjacent frequencies, share the same reference clock, and undergo nearly identical propagation paths to the receiver, resulting in strong coherence between the two signals. Joint processing of these signals can achieve optimal measurement performance due to the increased Gabor bandwidth and power. In this paper, we propose a universal scheme of asymmetric dual-band tracking (ASYM-DBT) to take advantage of the strong coherence, the increased Gabor bandwidth, and power of the two signals in achieving much-reduced thermal noise and more accurate ranging results when compared with the traditional single-band algorithm.
Teaching with a Dual-Channel Classroom Feedback System in the Digital Classroom Environment
ERIC Educational Resources Information Center
Yu, Yuan-Chih
2017-01-01
Teaching with a classroom feedback system can benefit both teaching and learning practices of interactivity. In this paper, we propose a dual-channel classroom feedback system integrated with a back-end e-Learning system. The system consists of learning agents running on the students' computers and a teaching agent running on the instructor's…
NASA Astrophysics Data System (ADS)
Liu, WenXiang; Mou, WeiHua; Wang, FeiXue
2012-03-01
As the introduction of triple-frequency signals in GNSS, the multi-frequency ionosphere correction technology has been fast developing. References indicate that the triple-frequency second order ionosphere correction is worse than the dual-frequency first order ionosphere correction because of the larger noise amplification factor. On the assumption that the variances of three frequency pseudoranges were equal, other references presented the triple-frequency first order ionosphere correction, which proved worse or better than the dual-frequency first order correction in different situations. In practice, the PN code rate, carrier-to-noise ratio, parameters of DLL and multipath effect of each frequency are not the same, so three frequency pseudorange variances are unequal. Under this consideration, a new unequal-weighted triple-frequency first order ionosphere correction algorithm, which minimizes the variance of the pseudorange ionosphere-free combination, is proposed in this paper. It is found that conventional dual-frequency first-order correction algorithms and the equal-weighted triple-frequency first order correction algorithm are special cases of the new algorithm. A new pseudorange variance estimation method based on the three carrier combination is also introduced. Theoretical analysis shows that the new algorithm is optimal. The experiment with COMPASS G3 satellite observations demonstrates that the ionosphere-free pseudorange combination variance of the new algorithm is smaller than traditional multi-frequency correction algorithms.
Truong, Quynh A; Knaapen, Paul; Pontone, Gianluca; Andreini, Daniele; Leipsic, Jonathon; Carrascosa, Patricia; Lu, Bin; Branch, Kelley; Raman, Subha; Bloom, Stephen; Min, James K
2015-10-01
Dual-energy CT (DECT) has potential to improve myocardial perfusion for physiologic assessment of coronary artery disease (CAD). Diagnostic performance of rest-stress DECT perfusion (DECTP) is unknown. DECIDE-Gold is a prospective multicenter study to evaluate the accuracy of DECT to detect hemodynamic (HD) significant CAD, as compared to fractional flow reserve (FFR) as a reference standard. Eligible participants are subjects with symptoms of CAD referred for invasive coronary angiography (ICA). Participants will undergo DECTP, which will be performed by pharmacological stress, and participants will subsequently proceed to ICA and FFR. HD-significant CAD will be defined as FFR ≤ 0.80. In those undergoing myocardial stress imaging (MPI) by positron emission tomography (PET), single photon emission computed tomography (SPECT) or cardiac magnetic resonance (CMR) imaging, ischemia will be graded by % ischemic myocardium. Blinded core laboratory interpretation will be performed for CCTA, DECTP, MPI, ICA, and FFR. Primary endpoint is accuracy of DECTP to detect ≥1 HD-significant stenosis at the subject level when compared to FFR. Secondary and tertiary endpoints are accuracies of combinations of DECTP at the subject and vessel levels compared to FFR and MPI. DECIDE-Gold will determine the performance of DECTP for diagnosing ischemia.
NASA Astrophysics Data System (ADS)
Ramm, Daniel
2018-02-01
Three dimensional dosimetry by optical CT readout of radiosensitive gels or solids has previously been indicated as a solution for measurement of radiotherapy 3D dose distributions. The clinical uptake of these dosimetry methods has been limited, partly due to impracticalities of the optical readout such as the expertise and labour required for refractive index fluid matching. In this work a fast laser beam optical CT scanner is described, featuring fluid-less and dual wavelength operation. A second laser with a different wavelength is used to provide an alternative reference scan to the commonly used pre-irradiation scan. Transmission data for both wavelengths is effectively acquired simultaneously, giving a single scan process. Together with the elimination of refractive index fluid matching issues, scanning practicality is substantially improved. Image quality and quantitative accuracy were assessed for both dual and single wavelength methods. The dual wavelength scan technique gave improvements in uniformity of reconstructed optical attenuation coefficients in the sample 3D volume. This was due to a reduction of artefacts caused by scan to scan changes. Optical attenuation measurement accuracy was similar for both dual and single wavelength modes of operation. These results established the basis for further work on dosimetric performance.
Assessment of the Performance of a Dual-Frequency Surface Reference Technique
NASA Technical Reports Server (NTRS)
Meneghini, Robert; Liao, Liang; Tanelli, Simone; Durden, Stephen
2013-01-01
The high correlation of the rain-free surface cross sections at two frequencies implies that the estimate of differential path integrated attenuation (PIA) caused by precipitation along the radar beam can be obtained to a higher degree of accuracy than the path-attenuation at either frequency. We explore this finding first analytically and then by examining data from the JPL dual-frequency airborne radar using measurements from the TC4 experiment obtained during July-August 2007. Despite this improvement in the accuracy of the differential path attenuation, solving the constrained dual-wavelength radar equations for parameters of the particle size distribution requires not only this quantity but the single-wavelength path attenuation as well. We investigate a simple method of estimating the single-frequency path attenuation from the differential attenuation and compare this with the estimate derived directly from the surface return.
Response simulation and theoretical calibration of a dual-induction resistivity LWD tool
NASA Astrophysics Data System (ADS)
Xu, Wei; Ke, Shi-Zhen; Li, An-Zong; Chen, Peng; Zhu, Jun; Zhang, Wei
2014-03-01
In this paper, responses of a new dual-induction resistivity logging-while-drilling (LWD) tool in 3D inhomogeneous formation models are simulated by the vector finite element method (VFEM), the influences of the borehole, invaded zone, surrounding strata, and tool eccentricity are analyzed, and calibration loop parameters and calibration coefficients of the LWD tool are discussed. The results show that the tool has a greater depth of investigation than that of the existing electromagnetic propagation LWD tools and is more sensitive to azimuthal conductivity. Both deep and medium induction responses have linear relationships with the formation conductivity, considering optimal calibration loop parameters and calibration coefficients. Due to the different depths of investigation and resolution, deep induction and medium induction are affected differently by the formation model parameters, thereby having different correction factors. The simulation results can provide theoretical references for the research and interpretation of the dual-induction resistivity LWD tools.
Volpe, Massimo; Danser, A H Jan; Menard, Joël; Waeber, Bernard; Mueller, Dominik N; Maggioni, Aldo P; Ruilope, Luis M
2012-04-01
Antagonism of renin-angiotensin-aldosterone system is exerted through angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists, renin inhibitors and mineralocorticoid receptor antagonists. These drugs have been successfully tested in numerous trials and in different clinical settings. The original indications of renin-angiotensin-aldosterone system blockers have progressively expanded from the advanced stages to the earlier stages of cardiorenal continuum. To optimize the degree of blockade of renin-angiotensin-aldosterone system, dose uptitrations of angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists or the use of a dual blockade, initially identified with the combination of angiotensin-converting enzyme inhibitors and angiotensin receptor antagonists, have been proposed. The data from the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial (ONTARGET) study do not support this specific dual blockade approach. However, the dual blockade of angiotensin-converting enzyme inhibitors/angiotensin receptor antagonists with direct renin inhibitors is currently under investigation while that based on an aldosterone blocker with any of the previous three drugs requires more evidence beyond heart failure. In this review, we revisited potential advantages of dual blockade of renin-angiotensin-aldosterone system in arterial hypertension and diabetes.
A dual cone-beam CT system for image guided radiotherapy: initial performance characterization.
Li, Hao; Giles, William; Bowsher, James; Yin, Fang-Fang
2013-02-01
The purpose of this study is to evaluate the performance of a recently developed benchtop dual cone-beam computed tomography (CBCT) system with two orthogonally placed tube∕detector sets. The benchtop dual CBCT system consists of two orthogonally placed 40 × 30 cm flat-panel detectors and two conventional x-ray tubes with two individual high-voltage generators sharing the same rotational axis. The x-ray source to detector distance is 150 cm and x-ray source to rotational axis distance is 100 cm for both subsystems. The objects are scanned through 200° of rotation. The dual CBCT system utilized 110° of projection data from one detector and 90° from the other while the two individual single CBCTs utilized 200° data from each detector. The system performance was characterized in terms of uniformity, contrast, spatial resolution, noise power spectrum, and CT number linearity. The uniformities, within the axial slice and along the longitudinal direction, and noise power spectrum were assessed by scanning a water bucket; the contrast and CT number linearity were measured using the Catphan phantom; and the spatial resolution was evaluated using a tungsten wire phantom. A skull phantom and a ham were also scanned to provide qualitative evaluation of high- and low-contrast resolution. Each measurement was compared between dual and single CBCT systems. Compared to single CBCT, the dual CBCT presented: (1) a decrease in uniformity by 1.9% in axial view and 1.1% in the longitudinal view, as averaged for four energies (80, 100, 125, and 150 kVp); (2) comparable or slightly better contrast (0∼25 HU) for low-contrast objects and comparable contrast for high-contrast objects; (3) comparable spatial resolution; (4) comparable CT number linearity with R(2) ≥ 0.99 for all four tested energies; (5) lower noise power spectrum in magnitude. Dual CBCT images of the skull phantom and the ham demonstrated both high-contrast resolution and good soft-tissue contrast. The performance of a benchtop dual CBCT imaging system has been characterized and is comparable to that of a single CBCT.
ERIC Educational Resources Information Center
Ricco, Robert B.; Overton, Willis F.
2011-01-01
Many current psychological models of reasoning minimize the role of deductive processes in human thought. In the present paper, we argue that deduction is an important part of ordinary cognition and we propose that a dual systems Competence [image omitted] Procedural processing model conceptualized within relational developmental systems theory…
p16/Ki-67 Dual Stain Cytology for Detection of Cervical Precancer in HPV-Positive Women.
Wentzensen, Nicolas; Fetterman, Barbara; Castle, Philip E; Schiffman, Mark; Wood, Shannon N; Stiemerling, Eric; Tokugawa, Diane; Bodelon, Clara; Poitras, Nancy; Lorey, Thomas; Kinney, Walter
2015-12-01
Human papillomavirus (HPV)-based cervical cancer screening requires triage markers to decide who should be referred to colposcopy. p16/Ki-67 dual stain cytology has been proposed as a biomarker for cervical precancers. We evaluated the dual stain in a large population of HPV-positive women. One thousand five hundred and nine HPV-positive women screened with HPV/cytology cotesting at Kaiser Permanente California were enrolled into a prospective observational study in 2012. Dual stain cytology was performed on residual Surepath material, and slides were evaluated for dual stain-positive cells. Disease endpoints were ascertained from the clinical database at KPNC. We evaluated the clinical performance of the assay among all HPV-positive women and among HPV-positive, cytology-negative women. We used internal benchmarks for clinical management to evaluate the clinical relevance of the dual stain assay. We evaluated sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the dual stain compared with Pap cytology. All statistical tests were two-sided. The dual stain had lower positivity (45.9%) compared with cytology at an ASC-US threshold (53.4%). For detection of CIN2+, the dual stain had similar sensitivity (83.4% vs 76.6%, P = .1), and statistically higher specificity (58.9% vs 49.6%, P < .001), PPV (21.0% vs 16.6%, P < .001), and NPV (96.4% vs 94.2%, P = .01) compared with cytology. Similar patterns were observed for CIN3+. Women with a positive test had high enough risk for referral to colposcopy, while the risk for women with negative tests was below a one-year return threshold based on current US management guidelines. Dual stain cytology showed good risk stratification for all HPV-positive women and for HPV-positive women with normal cytology. Additional follow-up is needed to determine how long dual stain negative women remain at low risk of precancer. Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.
Assimilation of Dual-Polarimetric Radar Observations with WRF GSI
NASA Technical Reports Server (NTRS)
Li, Xuanli; Mecikalski, John; Fehnel, Traci; Zavodsky, Bradley; Srikishen, Jayanthi
2014-01-01
Dual-polarimetric (dual-pol) radar typically transmits both horizontally and vertically polarized radio wave pulses. From the two different reflected power returns, more accurate estimate of liquid and solid cloud and precipitation can be provided. The upgrade of the traditional NWS WSR-88D radar to include dual-pol capabilities will soon be completed for the entire NEXRAD network. Therefore, the use of dual-pol radar network will have a broad impact in both research and operational communities. The assimilation of dual-pol radar data is especially challenging as few guidelines have been provided by previous research. It is our goal to examine how to best use dual-pol radar data to improve forecast of severe storm and forecast initialization. In recent years, the Development Testbed Center (DTC) has released the community Gridpoint Statistical Interpolation (GSI) DA system for the Weather Research and Forecasting (WRF) model. The community GSI system runs in independently environment, yet works functionally equivalent to operational centers. With collaboration with the NASA Short-term Prediction Research and Transition (SPoRT) Center, this study explores regional assimilation of the dual-pol radar variables from the WSR-88D radars for real case storms. Our presentation will highlight our recent effort on incorporating the horizontal reflectivity (ZH), differential reflectivity (ZDR), specific differential phase (KDP), and radial velocity (VR) data for initializing convective storms, with a significant focus being on an improved representation of hydrometeor fields. In addition, discussion will be provided on the development of enhanced assimilation procedures in the GSI system with respect to dual-pol variables. Beyond the dual-pol variable assimilation procedure developing within a GSI framework, highresolution (=1 km) WRF model simulations and storm scale data assimilation experiments will be examined, emphasizing both model initialization and short-term forecast of precipitation fields and processes. Further details of the methodology of data assimilation, the impact of different dual-pol variables, the influence on precipitation forecast will be presented at the conference.
Human Factors Engineering: Current and Emerging Dual-Use Applications
NASA Technical Reports Server (NTRS)
Chandlee, G. O.; Goldsberry, B. S.
1994-01-01
Human Factors Engineering is a multidisciplinary endeavor in which information pertaining to human characteristics is used in the development of systems and machines. Six representatives considered to be experts from the public and private sectors were surveyed in an effort to identify the potential dual-use of human factors technology. Each individual was asked to provide a rating as to the dual-use of 85 identified NASA technologies. Results of the survey were as follows: nearly 75 percent of the technologies were identified at least once as high dual-use by one of the six survey respondents, and nearly 25 percent of the identified NASA technologies were identified as high dual-use technologies by a majority of the respondents. The perceived level of dual-use appeared to be independent of the technology category. Successful identification of dual-use technology requires expanded input from industry. As an adjunct, cost-benefit analysis should be conducted to identify the feasibility of the dual-use technology. Concurrent with this effort should be an examination of precedents established by other technologies in other industrial settings. Advances in human factors and systems engineering are critical to reduce risk in any workplace and to enhance industrial competitiveness.
NASA Astrophysics Data System (ADS)
Al-Durgham, Kaleel; Lichti, Derek D.; Kuntze, Gregor; Ronsky, Janet
2017-06-01
High-speed biplanar videoradiography, or clinically referred to as dual fluoroscopy (DF), imaging systems are being used increasingly for skeletal kinematics analysis. Typically, a DF system comprises two X-ray sources, two image intensifiers and two high-speed video cameras. The combination of these elements provides time-series image pairs of articulating bones of a joint, which permits the measurement of bony rotation and translation in 3D at high temporal resolution (e.g., 120-250 Hz). Assessment of the accuracy of 3D measurements derived from DF imaging has been the subject of recent research efforts by several groups, however with methodological limitations. This paper presents a novel and simple accuracy assessment procedure based on using precise photogrammetric tools. We address the fundamental photogrammetry principles for the accuracy evaluation of an imaging system. Bundle adjustment with selfcalibration is used for the estimation of the system parameters. The bundle adjustment calibration uses an appropriate sensor model and applies free-network constraints and relative orientation stability constraints for a precise estimation of the system parameters. A photogrammetric intersection of time-series image pairs is used for the 3D reconstruction of a rotating planar object. A point-based registration method is used to combine the 3D coordinates from the intersection and independently surveyed coordinates. The final DF accuracy measure is reported as the distance between 3D coordinates from image intersection and the independently surveyed coordinates. The accuracy assessment procedure is designed to evaluate the accuracy over the full DF image format and a wide range of object rotation. Experiment of reconstruction of a rotating planar object reported an average positional error of 0.44 +/- 0.2 mm in the derived 3D coordinates (minimum 0.05 and maximum 1.2 mm).
May, Matthias S; Wüst, Wolfgang; Brand, Michael; Stahl, Christian; Allmendinger, Thomas; Schmidt, Bernhard; Uder, Michael; Lell, Michael M
2011-07-01
We sought to evaluate the image quality of iterative reconstruction in image space (IRIS) in half-dose (HD) datasets compared with full-dose (FD) and HD filtered back projection (FBP) reconstruction in abdominal computed tomography (CT). To acquire data with FD and HD simultaneously, contrast-enhanced abdominal CT was performed with a dual-source CT system, both tubes operating at 120 kV, 100 ref.mAs, and pitch 0.8. Three different image datasets were reconstructed from the raw data: Standard FD images applying FBP which served as reference, HD images applying FBP and HD images applying IRIS. For the HD data sets, only data from 1 tube detector-system was used. Quantitative image quality analysis was performed by measuring image noise in tissue and air. Qualitative image quality was evaluated according to the European Guidelines on Quality criteria for CT. Additional assessment of artifacts, lesion conspicuity, and edge sharpness was performed. : Image noise in soft tissue was substantially decreased in HD-IRIS (-3.4 HU, -22%) and increased in HD-FBP (+6.2 HU, +39%) images when compared with the reference (mean noise, 15.9 HU). No significant differences between the FD-FBP and HD-IRIS images were found for the visually sharp anatomic reproduction, overall diagnostic acceptability (P = 0.923), lesion conspicuity (P = 0.592), and edge sharpness (P = 0.589), while HD-FBP was rated inferior. Streak artifacts and beam hardening was significantly more prominent in HD-FBP while HD-IRIS images exhibited a slightly different noise pattern. Direct intrapatient comparison of standard FD body protocols and HD-IRIS reconstruction suggest that the latest iterative reconstruction algorithms allow for approximately 50% dose reduction without deterioration of the high image quality necessary for confident diagnosis.
Compact wearable dual-mode imaging system for real-time fluorescence image-guided surgery.
Zhu, Nan; Huang, Chih-Yu; Mondal, Suman; Gao, Shengkui; Huang, Chongyuan; Gruev, Viktor; Achilefu, Samuel; Liang, Rongguang
2015-09-01
A wearable all-plastic imaging system for real-time fluorescence image-guided surgery is presented. The compact size of the system is especially suitable for applications in the operating room. The system consists of a dual-mode imaging system, see-through goggle, autofocusing, and auto-contrast tuning modules. The paper will discuss the system design and demonstrate the system performance.
Development of the Dual Aerodynamic Nozzle Model for the NTF Semi-Span Model Support System
NASA Technical Reports Server (NTRS)
Jones, Greg S.; Milholen, William E., II; Goodliff, Scott L.
2011-01-01
The recent addition of a dual flow air delivery system to the NASA Langley National Transonic Facility was experimentally validated with a Dual Aerodynamic Nozzle semi-span model. This model utilized two Stratford calibration nozzles to characterize the weight flow system of the air delivery system. The weight flow boundaries for the air delivery system were identified at mildly cryogenic conditions to be 0.1 to 23 lbm/sec for the high flow leg and 0.1 to 9 lbm/sec for the low flow leg. Results from this test verified system performance and identified problems with the weight-flow metering system that required the vortex flow meters to be replaced at the end of the test.
Development of self-control in children aged 3 to 9 years: Perspective from a dual-systems model
Tao, Ting; Wang, Ligang; Fan, Chunlei; Gao, Wenbin
2014-01-01
The current study tested a set of interrelated theoretical propositions based on a dual-systems model of self-control. Data were collected from 2135 children aged 3 to 9 years. The results suggest that (a) there was positive growth in good self-control, whereas poor control remained relatively stable; and (b) girls performed better than boys on tests of good self-control. The results are discussed in terms of their implications for a dual-systems model of self-control theory and future empirical work. PMID:25501669
Can Questions Facilitate Learning from Illustrated Science Texts?
ERIC Educational Resources Information Center
Iding, Marie K.
1997-01-01
Examines the effectiveness of using questions to facilitate processing of diagrams in science texts. Investigates three different elements in experiments on college students. Finds that questions about illustrations do not facilitate learning. Discusses findings with reference to cognitive load theory, the dual coding perspective, and the…
Interactive Video: One Monitor or Two?
ERIC Educational Resources Information Center
Cline, William J.
1991-01-01
Analysis of the effects of an interactive video workstation during lessons about Spanish culture suggested that the use of single or dual monitors was not an important factor in student learning, although there were some cost advantages associated with the two-monitor workstation design. (seven references) (Author/CB)
DSLM Instructional Approach to Conceptual Change Involving Thermal Expansion.
ERIC Educational Resources Information Center
She, Hsiao-Ching
2003-01-01
Examines the process of student conceptual change regarding thermal expansion using the Dual Situated Learning Model (DSLM) as an instructional approach. Indicates that DSLM promotes conceptual change and holds great potential to facilitate the process through classroom instruction at all levels. (Contains 38 references.) (Author/NB)
Noh, G; Jang, E H
2014-01-01
Specific oral tolerance induction (SOTI) for IgE-mediated food allergy (IFA) can be successfully achieved using interfero gamma (classic SOTI). In this study, a tolerable dose was introduced during tolerance induction with interferon gamma (dual SOTI), and its effectiveness was evaluated. The study population comprised 25 IFA patients. Blood samples were taken for analysis, including complete blood count with differential counts of eosinophils, serum total IgE levels, and specific IgE for allergenic foods. Skin prick tests were conducted with the allergens. Oral food challenges were performed to diagnose IFA. Ten patients received dual SOTI, 5 received classic SOTI, 5 received SOTI without interferon gamma (original SOTI), and 5 were not treated (controls). Patients treated with dual SOTI and classic SOTI using interferon gamma became tolerant to the allergenic food. The tolerable dose was introduced successfully in dual SOTI. It was difficult to proceed with the same dosing protocol used for classic SOTI in cases treated with original SOTI. Following dual SOTI, the systemic reaction to oral intake subsided, but the local skin reaction to contact with the allergenic food persisted. Dual SOTI is an improved protocol for SOTI using interferon gamma for IFA.The local skin reaction and systemic reaction to oral intake were dissociated following dual SOTI. In cases of food allergy, tolerance appears to result from desensitization to allergens.
Dual renin-angiotensin-aldosterone system blockade for diabetic kidney disease.
Pichler, Raimund H; de Boer, Ian H
2010-08-01
Blockade of the renin-angiotensin-aldosterone system (RAAS) prevents the development and progression of diabetic kidney disease (DKD). It is controversial whether the simultaneous use of two RAAS inhibitors (ie, dual RAAS blockade) further improves renal outcomes. This review examines the scientific rationale and current clinical evidence addressing the use of dual RAAS blockade to prevent and treat DKD. It is concluded that dual RAAS blockade should not be routinely applied to patients with low or moderate risk of progressive kidney disease (normoalbuminuria or microalbuminuria with preserved glomerular filtration rate). For patients with high risk of progressive kidney disease (substantial albuminuria or impaired glomerular filtration rate), clinicians should carefully weigh the potential risks and benefits of dual RAAS blockade on an individual basis until ongoing clinical trials provide further insight.
On-chip dual-comb based on quantum cascade laser frequency combs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Villares, G., E-mail: gustavo.villares@phys.ethz.ch; Wolf, J.; Kazakov, D.
2015-12-21
Dual-comb spectroscopy is emerging as an appealing application of mid-infrared frequency combs for high-resolution molecular spectroscopy, as it leverages on the unique coherence properties of frequency combs. Here, we present an on-chip dual-comb source based on mid-infrared quantum cascade laser frequency combs. Control of the combs repetition and offset frequencies is obtained by integrating micro-heaters next to each laser. We show that a full control of the dual-comb system is possible, by measuring a multi-heterodyne beating corresponding to an optical bandwidth of 32 cm{sup −1} centered at 1330 cm{sup −1} (7.52 μm), demonstrating that this device represents a critical step towards compact dual-combmore » systems.« less
NASA Astrophysics Data System (ADS)
Chen, Dechao; Zhang, Yunong
2017-10-01
Dual-arm redundant robot systems are usually required to handle primary tasks, repetitively and synchronously in practical applications. In this paper, a jerk-level synchronous repetitive motion scheme is proposed to remedy the joint-angle drift phenomenon and achieve the synchronous control of a dual-arm redundant robot system. The proposed scheme is novelly resolved at jerk level, which makes the joint variables, i.e. joint angles, joint velocities and joint accelerations, smooth and bounded. In addition, two types of dynamics algorithms, i.e. gradient-type (G-type) and zeroing-type (Z-type) dynamics algorithms, for the design of repetitive motion variable vectors, are presented in detail with the corresponding circuit schematics. Subsequently, the proposed scheme is reformulated as two dynamical quadratic programs (DQPs) and further integrated into a unified DQP (UDQP) for the synchronous control of a dual-arm robot system. The optimal solution of the UDQP is found by the piecewise-linear projection equation neural network. Moreover, simulations and comparisons based on a six-degrees-of-freedom planar dual-arm redundant robot system substantiate the operation effectiveness and tracking accuracy of the robot system with the proposed scheme for repetitive motion and synchronous control.
Chen, Haiping; Li, Meina; Dai, Zhixin; Deng, Qiangyu; Zhang, Lulu
2016-01-01
Dual practice is defined as a physician's performance of medical activities in different health care institutions (two or more) simultaneously. This study aimed to examine the perception and acceptance of medical staff and outpatients of dual practice and explore the possible factors affecting people's perception. A cross-sectional study was conducted in 13 public hospitals in Shanghai. Participants included medical staff and outpatients. We distributed 1,000 questionnaires to each participant group, and the response rates were 66.7% and 69.4%, respectively. Statistical differences in variables were tested, and multinomial logistic regression methods were employed for statistical analysis. The study included two parts: medical staff survey and outpatient survey. The results of medical staff survey showed that 63.0% of the respondents supported dual practice. Medical staff who belonged to the surgical department or held positive belief of dual practice were more willing to participate in dual practice. Moreover, the publicity activities of dual practice and hospitals' human resource management system were important factors affecting the willingness of the medical staff. The results of outpatient survey showed that 44.5% of respondents believed that dual practice could reduce difficulty in consulting a doctor. Regarding the perceived benefits of dual practice, the proportion of outpatients who believed that dual practice could meet the demand for health convenience, minor illness, and chronic disease were 45.4%, 42.4%, and 53.7%, respectively. Additionally, demographic characteristics significantly influenced the perception of outpatients. This study confirmed that both medical staff and outpatients generally held positive attitudes toward dual practice. Medical staff who belonged to the surgical department or held positive belief of dual practice were more willing to participate in dual practice. Moreover, the existence of publicity activities and more flexible management system of hospitals' human resource would promote physicians' willingness to participate in dual practice. In addition, perception of outpatients of dual practice was affected by demographic characteristics.
Chen, Haiping; Li, Meina; Dai, Zhixin; Deng, Qiangyu; Zhang, Lulu
2016-01-01
Objective Dual practice is defined as a physician’s performance of medical activities in different health care institutions (two or more) simultaneously. This study aimed to examine the perception and acceptance of medical staff and outpatients of dual practice and explore the possible factors affecting people’s perception. Methods A cross-sectional study was conducted in 13 public hospitals in Shanghai. Participants included medical staff and outpatients. We distributed 1,000 questionnaires to each participant group, and the response rates were 66.7% and 69.4%, respectively. Statistical differences in variables were tested, and multinomial logistic regression methods were employed for statistical analysis. Results The study included two parts: medical staff survey and outpatient survey. The results of medical staff survey showed that 63.0% of the respondents supported dual practice. Medical staff who belonged to the surgical department or held positive belief of dual practice were more willing to participate in dual practice. Moreover, the publicity activities of dual practice and hospitals’ human resource management system were important factors affecting the willingness of the medical staff. The results of outpatient survey showed that 44.5% of respondents believed that dual practice could reduce difficulty in consulting a doctor. Regarding the perceived benefits of dual practice, the proportion of outpatients who believed that dual practice could meet the demand for health convenience, minor illness, and chronic disease were 45.4%, 42.4%, and 53.7%, respectively. Additionally, demographic characteristics significantly influenced the perception of outpatients. Conclusion This study confirmed that both medical staff and outpatients generally held positive attitudes toward dual practice. Medical staff who belonged to the surgical department or held positive belief of dual practice were more willing to participate in dual practice. Moreover, the existence of publicity activities and more flexible management system of hospitals’ human resource would promote physicians’ willingness to participate in dual practice. In addition, perception of outpatients of dual practice was affected by demographic characteristics. PMID:27621600
Gravity sensing using Very Long Baseline Atom Interferometry
NASA Astrophysics Data System (ADS)
Schlippert, D.; Wodey, E.; Meiners, C.; Tell, D.; Schubert, C.; Ertmer, W.; Rasel, E. M.
2017-12-01
Very Long Baseline Atom Interferometry (VLBAI) has applications in high-accuracy absolute gravimetry, gravity-gradiometry, and for tests of fundamental physics. Thanks to the quadratic scaling of the phase shift with increasing free evolution time, extending the baseline of atomic gravimeters from tens of centimeters to meters puts resolutions of 10-13g and beyond in reach.We present the design and progress of key elements of the VLBAI-test stand: a dual-species source of Rb and Yb, a high-performance two-layer magnetic shield, and an active vibration isolation system allowing for unprecedented stability of the mirror acting as an inertial reference. We envisage a vibration-limited short-term sensitivity to gravitational acceleration of 1x10-8 m/s-2Hz-1/2 and up to a factor of 25 improvement when including additional correlation with a broadband seismometer. Here, the supreme long-term stability of atomic gravity sensors opens the route towards competition with superconducting gravimeters. The operation of VLBAI as a differential dual-species gravimeter using ultracold mixtures of Yb and Rb atoms enables quantum tests of the universality of free fall (UFF) at an unprecedented level of <10-13, potentially surpassing the best experiments to date.
Gravity sensing using Very Long Baseline Atom Interferometry
NASA Astrophysics Data System (ADS)
Schlippert, Dennis; Wodey, Étienne; Meiners, Christian; Tell, Dorothee; Schubert, Christian; Ertmer, Wolfgang; Rasel, Ernst M.
2017-04-01
Very Long Baseline Atom Interferometry (VLBAI) has applications in high-accuracy absolute gravimetry, gravity-gradiometry, and for tests of fundamental physics. Thanks to the quadratic scaling of the phase shift with increasing free evolution time, extending the baseline of atomic gravimeters from tens of centimeters to meters puts resolutions of 10-13 g and beyond in reach. We present the design and progress of key elements of the VLBAI-test stand: a dual-species source of Rb and Yb, a high-performance two-layer magnetic shield, and an active vibration isolation system allowing for unprecedented stability of the mirror acting as an inertial reference. We envisage a vibration-limited short-term sensitivity to gravitational acceleration of 1 .10-8 m/s2 / Hz1/2 and up to a factor of 25 improvement when including additional correlation with a broadband seismometer. Here, the supreme long-term stability of atomic gravity sensors opens the route towards competition with superconducting gravimeters. The operation of VLBAI as a differential dual-species gravimeter using ultracold mixtures of Yb and Rb atoms enables quantum tests of the universality of free fall (UFF) at an unprecedented level of <=10-13 , potentially surpassing the best experiments to date.
GOES-16 On-Orbit Dual Isolation Performance Characterization Results
NASA Technical Reports Server (NTRS)
Carter, Delano; Clapp, Brian; Early, Derrick; Freesland, Douglas; Chapel, Jim; Bailey, Robert; Krimchansky, Alexander
2016-01-01
The Geostationary Operational Environmental Satellite-R Series (GOES-R) is the first of the next generation geostationary weather satellites. GOES-R successfully launched on November19, 2016 and renamed GOES-16 upon entering geostationary orbit. Subsequently, GOES-16post-launch testing began. This paper presents the GOES-16 Satellite Dynamic Interaction Characterization results for the Earth Pointed Platform (EPP) stowed, referred to as the Reaction Wheel Assembly (RWA) Isolation Only configuration, and deployed, referred to as the Dual Isolation configuration. GOES-R represents a quantum increase in Earth and solar weather observation capabilities, with 4 times the resolution, 5 times the observation rate, and 3 times the number of spectral bands for Earth observations. With the improved resolution, comes the instrument suites increased sensitivity to disturbances over a broad spectrum 0-512Hz. Sources of disturbance include reaction wheels, thruster firings for station keeping and momentum management, gimbal motion, and internal instrument disturbances. To minimize the impact of these disturbances, the baseline design included an EPP, a stiff optical bench to which the two nadir pointed instruments are collocated together with the Guidance Navigation Control (GNC) star trackers and Inertial Measurement Units (IMUs). The EPP is passively isolated from the spacecraft bus with Honeywell D-Strut isolators providing attenuation for frequencies above 5 Hz in all six degrees-of-freedom. To reduce the risk of wheel disturbances impacting performance, a secondary passive isolation system manufactured by Moog CSA Engineering was incorporated under each of the six 160 Nms reaction wheels, tuned to provide attenuation at frequencies above 50 Hz. Integrated wheel and isolator testing was performed on a Kistler table at NASA Goddard Space Flight Center. Pre-launch Satellite Dynamic Interaction Characterization high-fidelity simulations and ground testing were conducted to evaluate jitter performance for two cases: 1) deployed EPP and reaction wheel (Dual Isolation) and 2) EPP hard mounted (RWA Isolation Only) to the spacecraft. A comparison of pre-launch to post-launch Satellite Dynamic Interaction Characterization results are also presented in this paper.
Behavioral interventions for improving dual-method contraceptive use.
Lopez, Laureen M; Stockton, Laurie L; Chen, Mario; Steiner, Markus J; Gallo, Maria F
2014-03-30
Dual-method contraception refers to using condoms as well as another modern method of contraception. The latter (usually non-barrier) method is commonly hormonal (e.g., oral contraceptives) or a non-hormonal intrauterine device. Use of two methods can better prevent pregnancy and the transmission of HIV and other sexually transmitted infections (STIs) compared to single-method use. Unprotected sex increases risk for disease, disability, and mortality in many areas due to the prevalence and incidence of HIV/STI. Millions of women, especially in lower-resource areas, also have an unmet need for protection against unintended pregnancy. We examined comparative studies of behavioral interventions for improving use of dual methods of contraception. Dual-method use refers to using condoms as well as another modern contraceptive method. Our intent was to identify effective interventions for preventing pregnancy as well as HIV/STI transmission. Through January 2014, we searched MEDLINE, CENTRAL, POPLINE, EMBASE, COPAC, and Open Grey. In addition, we searched ClinicalTrials.gov and ICTRP for current trials and trials with relevant data or reports. We examined reference lists of pertinent papers, including review articles, for additional reports. Studies could be either randomized or non-randomized. They examined a behavioral intervention with an educational or counseling component to encourage or improve the use of dual methods, i.e., condoms and another modern contraceptive. The intervention had to address preventing pregnancy as well as the transmission of HIV/STI. The program or service could be targeted to individuals, couples, or communities. The comparison condition could be another behavioral intervention to improve contraceptive use, usual care, other health education, or no intervention.Studies had to report use of dual methods, i.e., condoms plus another modern contraceptive method. We focused on the investigator's assessment of consistent dual-method use or use at last sex. Outcomes had to be measured at least three months after the behavioral intervention began. Two authors evaluated abstracts for eligibility and extracted data from included studies. For the dichotomous outcomes, the Mantel-Haenszel odds ratio (OR) with 95% CI was calculated using a fixed-effect model. Where studies used adjusted analysis, we presented the results as reported by the investigators. No meta-analysis was conducted due to differences in interventions and outcome measures. We identified four studies that met the inclusion criteria: three randomized controlled trials and a pilot study for one of the included trials. The interventions differed markedly: computer-delivered, individually tailored sessions; phone counseling added to clinic counseling; and case management plus a peer-leadership program. The latter study, which addressed multiple risks, showed an effect on contraceptive use. Compared to the control group, the intervention group was more likely to report consistent dual-method use, i.e., oral contraceptives and condoms. The reported relative risk was 1.58 at 12 months (95% CI 1.03 to 2.43) and 1.36 at 24 months (95% CI 1.01 to 1.85). The related pilot study showed more reporting of consistent dual-method use for the intervention group compared to the control group (reported P value = 0.06); the investigators used a higher alpha (P < 0.10) for this pilot study. The other two trials did not show any significant difference between the study groups in reported dual-method use or in test results for pregnancy or STIs at 12 or 24 months. We found few behavioral interventions for improving dual-method contraceptive use and little evidence of effectiveness. A multifaceted program showed some effect but only had self-reported outcomes. Two trials were more applicable to clinical settings and had objective outcomes measures, but neither showed any effect. The included studies had adequate information on intervention fidelity and sufficient follow-up periods for change to occur. However, the overall quality of evidence was considered low. Two trials had design limitations and two had high losses to follow up, as often occurs in contraceptive trials. Good quality studies are still needed of carefully designed and implemented programs or services.
Manfredi, Roberto; Calza, Leonardo; Chiodo, Francesco
2002-12-01
A case report of a patient who discovered his HIV infection concurrently with an advanced immunodeficiency and a dual Candida albicans and Cryptococcus neoformans fungaemia is discussed with reference to the changing epidemiology and clinical features of HIV infection and AIDS in the highly active antiretroviral therapy (HAART) era. The tendency to develop multiple concomitant AIDS-defining illnesses at the time of first hospitalisation seems to be an increasing feature in patients who remain unaware of or neglect their HIV disease and who are still at risk of opportunist infections even with the availability of HAART.
Development of anti-scale poly(aspartic acid-citric acid) dual polymer systems for water treatment.
Nayunigari, Mithil Kumar; Gupta, Sanjay Kumar; Kokkarachedu, Varaprasad; Kanny, K; Bux, F
2014-01-01
The formation of calcium sulphate and calcium carbonate scale poses major problems in heat exchangers and water cooling systems, thereby affecting the performance of these types of equipment. In order to inhibit these scale formations, new types of biodegradable water soluble single polymer and dual poly(aspartic acid-citric acid) polymers were developed and tested. The effectiveness of single polymer and four different compositions of poly aspartic acid and citric acid dual polymer systems as scale inhibitors were evaluated. Details of the synthesis, thermal stability, scale inhibition and the morphological characterization of single and dual polymers are presented in this scientific paper. It was found that the calcium sulphate scale inhibition rate was in the range 76.06-91.45%, while the calcium carbonate scale inhibition rate observed was in the range 23.37-30.0% at 65-70 °C. The finding suggests that the water soluble dual polymers are very effective in sulphate scale inhibition in comparison of calcium carbonate scale inhibition.
Pope, Charlene A.; Davis, Boyd H.; Wine, Leticia; Nemeth, Lynne S.; Axon, Robert N.
2018-01-01
Among Veterans, heart failure (HF) contributes to frequent emergency department visits and hospitalization. Dual health care system use (dual use) occurs when Veterans Health Administration (VA) enrollees also receive care from non-VA sources. Mounting evidence suggests that dual use decreases efficiency and patient safety. This qualitative study used constructivist grounded theory and content analysis to examine decision making among 25 Veterans with HF, for similarities and differences between all-VA users and dual users. In general, all-VA users praised specific VA providers, called services helpful, and expressed positive capacity for managing HF. In addition, several Veterans who described inadvertent one-time non-VA health care utilization in emergent situations more closely mirrored all-VA users. By contrast, committed dual users more often reported unmet needs, nonresponse to VA requests, and faster services in non-VA facilities. However, a primary trigger for dual use was VA telephone referral for escalating symptoms, instead of care coordination or primary/specialty care problem-solving. PMID:29482411
Naeem, Muhammad; Cao, Jiafu; Choi, Moonjeong; Kim, Woo Seong; Moon, Hyung Ryong; Lee, Bok Luel; Kim, Min-Soo; Jung, Yunjin; Yoo, Jin-Wook
2015-01-01
Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitive nanoparticles using enzyme-sensitive azo-polyurethane and pH-sensitive methacrylate copolymer for the treatment of colitis. The therapeutic potential of the enzyme/pH dual-sensitive nanoparticles was evaluated using a rat colitis model and compared to single pH-triggered nanoparticles. Clinical activity scores, colon/body weight ratios, myeloperoxidase activity, and proinflammatory cytokine levels were markedly decreased by dual-sensitive nanoparticles compared to single pH-triggered nanoparticles and budesonide solution. Moreover, dual-sensitive nanoparticles accumulated selectively in inflamed segments of the colon. In addition, dual-sensitive nanoparticle plasma concentrations were lower than single pH-triggered nanoparticles, and no noticeable in vitro or in vivo toxicity was observed. Our results demonstrate that enzyme/pH dual-sensitive nanoparticles are an effective and safe colon-targeted delivery system for colitis therapy.
Naeem, Muhammad; Cao, Jiafu; Choi, Moonjeong; Kim, Woo Seong; Moon, Hyung Ryong; Lee, Bok Luel; Kim, Min-Soo; Jung, Yunjin; Yoo, Jin-Wook
2015-01-01
Current colon-targeted drug-delivery approaches for colitis therapy often utilize single pH-triggered systems, which are less reliable due to the variation of gut pH in individuals and in disease conditions. Herein, we prepared budesonide-loaded dual-sensitive nanoparticles using enzyme-sensitive azo-polyurethane and pH-sensitive methacrylate copolymer for the treatment of colitis. The therapeutic potential of the enzyme/pH dual-sensitive nanoparticles was evaluated using a rat colitis model and compared to single pH-triggered nanoparticles. Clinical activity scores, colon/body weight ratios, myeloperoxidase activity, and proinflammatory cytokine levels were markedly decreased by dual-sensitive nanoparticles compared to single pH-triggered nanoparticles and budesonide solution. Moreover, dual-sensitive nanoparticles accumulated selectively in inflamed segments of the colon. In addition, dual-sensitive nanoparticle plasma concentrations were lower than single pH-triggered nanoparticles, and no noticeable in vitro or in vivo toxicity was observed. Our results demonstrate that enzyme/pH dual-sensitive nanoparticles are an effective and safe colon-targeted delivery system for colitis therapy. PMID:26213469
Construction of Polarimetric Radar-Based Reference Rain Maps for the Iowa Flood Studies Campaign
NASA Technical Reports Server (NTRS)
Petersen, Walter; Wolff, David; Krajewski, Witek; Gatlin, Patrick
2015-01-01
The Global Precipitation Measurement (GPM) Mission Iowa Flood Studies (IFloodS) campaign was conducted in central and northeastern Iowa during the months of April-June, 2013. Specific science objectives for IFloodS included quantification of uncertainties in satellite and ground-based estimates of precipitation, 4-D characterization of precipitation physical processes and associated parameters (e.g., size distributions, water contents, types, structure etc.), assessment of the impact of precipitation estimation uncertainty and physical processes on hydrologic predictive skill, and refinement of field observations and data analysis approaches as they pertain to future GPM integrated hydrologic validation and related field studies. In addition to field campaign archival of raw and processed satellite data (including precipitation products), key ground-based platforms such as the NASA NPOL S-band and D3R Ka/Ku-band dual-polarimetric radars, University of Iowa X-band dual-polarimetric radars, a large network of paired rain gauge platforms, and a large network of 2D Video and Parsivel disdrometers were deployed. In something of a canonical approach, the radar (NPOL in particular), gauge and disdrometer observational assets were deployed to create a consistent high-quality distributed (time and space sampling) radar-based ground "reference" rainfall dataset, with known uncertainties, that could be used for assessing the satellite-based precipitation products at a range of space/time scales. Subsequently, the impact of uncertainties in the satellite products could be evaluated relative to the ground-benchmark in coupled weather, land-surface and distributed hydrologic modeling frameworks as related to flood prediction. Relative to establishing the ground-based "benchmark", numerous avenues were pursued in the making and verification of IFloodS "reference" dual-polarimetric radar-based rain maps, and this study documents the process and results as they pertain specifically to efforts using the NPOL radar dataset. The initial portions of the "process" involved dual-polarimetric quality control procedures which employed standard phase and correlation-based approaches to removal of clutter and non-meteorological echo. Calculation of a scale-adaptive KDP was accomplished using the method of Wang and Chandrasekar (2009; J. Atmos. Oceanic Tech.). A dual-polarimetric blockage algorithm based on Lang et al. (2009; J. Atmos. Oceanic Tech.) was then implemented to correct radar reflectivity and differential reflectivity at low elevation angles. Next, hydrometeor identification algorithms were run to identify liquid and ice hydrometeors. After the quality control and data preparation steps were completed several different dual-polarimetric rain estimation algorithms were employed to estimate rainfall rates using rainfall scans collected approximately every two to three minutes throughout the campaign. These algorithms included a polarimetrically-tuned Z-R algorithm that adjusts for drop oscillations (via Bringi et al., 2004, J. Atmos. Oceanic Tech.), and several different hybrid polarimetric variable approaches, including one that made use of parameters tuned to IFloodS 2D Video Disdrometer measurements. Finally, a hybrid scan algorithm was designed to merge the rain rate estimates from multiple low level elevation angle scans (where blockages could not be appropriately corrected) in order to create individual low-level rain maps. Individual rain maps at each time step were subsequently accumulated over multiple time scales for comparison to gauge network data. The comparison results and overall error character depended strongly on rain event type, polarimetric estimator applied, and range from the radar. We will present the outcome of these comparisons and their impact on constructing composited "reference" rainfall maps at select time and space scales.
Use of the dual force system to correct chronic knee deformities due to severe haemophilia.
Kale, J S; Ghosh, K; Mohanty, D; Pathare, A V; Jijina, F
2000-05-01
In this study, the use of the dual force system to correct recent or relatively longstanding knee deformities in ten patients is described. (Nine of the patients had severe haemophilia and one had severe von Willebrand's disease.) The mean duration of deformity in these patients was 10 months. The mean range of movement at the affected knee joints increased from 50 degrees at pre-intervention to 110 degrees following 6 weeks of application of the dual force system. In nine of ten patients (90%) the residual flexion deformity ranged from 0 degrees to 10 degrees. The dual force system offers an easily affordable and effective means of correcting a flexion deformity of the knee joint in severely affected haemophilia and allied disorders. More extensive use of this technique in different centres is required to determine its place in the day-to-day management of such patients.
Li, Jianbo; Zhang, Jinjie; Fu, Yao; Sun, Xun; Gong, Tao; Jiang, Jinghui; Zhang, Zhirong
2015-08-28
To inhibit both the local and systemic complications with acute pancreatitis, an effective therapy requires a drug delivery system that can efficiently overcome the blood-pancreas barrier while achieving lung-specific accumulation. Here, we report the first dual pancreas- and lung-targeting therapeutic strategy mediated by a phenolic propanediamine moiety for the treatment of acute pancreatitis. Using the proposed dual-targeting ligand, an anti-inflammatory compound Rhein has been tailored to preferentially accumulate in the pancreas and lungs with rapid distribution kinetics, excellent tissue-penetrating properties and minimum toxicity. Accordingly, the drug-ligand conjugate remarkably downregulated the proinflammatory cytokines in the target organs thus effectively inhibiting local pancreatic and systemic inflammation in rats. The dual-specific targeting therapeutic strategy may help pave the way for targeted drug delivery to treat complicated inflammatory diseases. Copyright © 2015 Elsevier B.V. All rights reserved.
Yang, Jian-Feng; Zhao, Zhen-Hua; Zhang, Yu; Zhao, Li; Yang, Li-Ming; Zhang, Min-Ming; Wang, Bo-Yin; Wang, Ting; Lu, Bao-Chun
2016-04-07
To investigate the feasibility of a dual-input two-compartment tracer kinetic model for evaluating tumorous microvascular properties in advanced hepatocellular carcinoma (HCC). From January 2014 to April 2015, we prospectively measured and analyzed pharmacokinetic parameters [transfer constant (Ktrans), plasma flow (Fp), permeability surface area product (PS), efflux rate constant (kep), extravascular extracellular space volume ratio (ve), blood plasma volume ratio (vp), and hepatic perfusion index (HPI)] using dual-input two-compartment tracer kinetic models [a dual-input extended Tofts model and a dual-input 2-compartment exchange model (2CXM)] in 28 consecutive HCC patients. A well-known consensus that HCC is a hypervascular tumor supplied by the hepatic artery and the portal vein was used as a reference standard. A paired Student's t-test and a nonparametric paired Wilcoxon rank sum test were used to compare the equivalent pharmacokinetic parameters derived from the two models, and Pearson correlation analysis was also applied to observe the correlations among all equivalent parameters. The tumor size and pharmacokinetic parameters were tested by Pearson correlation analysis, while correlations among stage, tumor size and all pharmacokinetic parameters were assessed by Spearman correlation analysis. The Fp value was greater than the PS value (FP = 1.07 mL/mL per minute, PS = 0.19 mL/mL per minute) in the dual-input 2CXM; HPI was 0.66 and 0.63 in the dual-input extended Tofts model and the dual-input 2CXM, respectively. There were no significant differences in the kep, vp, or HPI between the dual-input extended Tofts model and the dual-input 2CXM (P = 0.524, 0.569, and 0.622, respectively). All equivalent pharmacokinetic parameters, except for ve, were correlated in the two dual-input two-compartment pharmacokinetic models; both Fp and PS in the dual-input 2CXM were correlated with Ktrans derived from the dual-input extended Tofts model (P = 0.002, r = 0.566; P = 0.002, r = 0.570); kep, vp, and HPI between the two kinetic models were positively correlated (P = 0.001, r = 0.594; P = 0.0001, r = 0.686; P = 0.04, r = 0.391, respectively). In the dual input extended Tofts model, ve was significantly less than that in the dual input 2CXM (P = 0.004), and no significant correlation was seen between the two tracer kinetic models (P = 0.156, r = 0.276). Neither tumor size nor tumor stage was significantly correlated with any of the pharmacokinetic parameters obtained from the two models (P > 0.05). A dual-input two-compartment pharmacokinetic model (a dual-input extended Tofts model and a dual-input 2CXM) can be used in assessing the microvascular physiopathological properties before the treatment of advanced HCC. The dual-input extended Tofts model may be more stable in measuring the ve; however, the dual-input 2CXM may be more detailed and accurate in measuring microvascular permeability.
Soliton microcomb range measurement
NASA Astrophysics Data System (ADS)
Suh, Myoung-Gyun; Vahala, Kerry J.
2018-02-01
Laser-based range measurement systems are important in many application areas, including autonomous vehicles, robotics, manufacturing, formation flying of satellites, and basic science. Coherent laser ranging systems using dual-frequency combs provide an unprecedented combination of long range, high precision, and fast update rate. We report dual-comb distance measurement using chip-based soliton microcombs. A single pump laser was used to generate dual-frequency combs within a single microresonator as counterpropagating solitons. We demonstrated time-of-flight measurement with 200-nanometer precision at an averaging time of 500 milliseconds within a range ambiguity of 16 millimeters. Measurements at distances up to 25 meters with much lower precision were also performed. Our chip-based source is an important step toward miniature dual-comb laser ranging systems that are suitable for photonic integration.
Reddy, Nagam Raja; Reddy, Jakranpally Sathya; Padmaja, Bramha Josyula Indira; Reddy, Budigi Madan Mohan; Sunil, Motupalli; Reddy, Bommireddy Tejeswar
2016-01-01
To evaluate the accuracy of dies made from dual arch impressions using different sectional dual arch trays, combinations of elastomeric impression materials, and the sequence of pour of dies. The dual arch impression materials were grouped into three groups depending on the combination of impression materials used and each group is subdivided into four subgroups. A sample size of 8 in each subgroup yielding a total 96 impressions will be made into three groups of 32 each (Group I, II, and III). Group I constitute impressions made using monophase (M) impression material, Group II constitute impressions made using combination of heavy body and light body (HL), and Group III constitute impressions made using combination of putty and light body (PL). Dies obtained were evaluated with a travelling microscope to measure the buccolingual width of the tooth at the margin by using the sharp corners of the notches as reference points. Descriptive analysis namely mean and standard deviation, one-way analysis of variance test. The results obtained in this study indicate that though not statistically significant, the metal dual arch trays performed better when compared to the plastic trays in reproducing die dimensions. From the results obtained, dies poured from combination of heavy body and light body impressions using plastic or metal dual arch trays showed least variation in bucco-lingual dimension from master model.
Reddy, Nagam Raja; Reddy, Jakranpally Sathya; Padmaja, Bramha Josyula Indira; Reddy, Budigi Madan Mohan; Sunil, Motupalli; Reddy, Bommireddy Tejeswar
2016-01-01
Aims: To evaluate the accuracy of dies made from dual arch impressions using different sectional dual arch trays, combinations of elastomeric impression materials, and the sequence of pour of dies. Subjects and Methods: The dual arch impression materials were grouped into three groups depending on the combination of impression materials used and each group is subdivided into four subgroups. A sample size of 8 in each subgroup yielding a total 96 impressions will be made into three groups of 32 each (Group I, II, and III). Group I constitute impressions made using monophase (M) impression material, Group II constitute impressions made using combination of heavy body and light body (HL), and Group III constitute impressions made using combination of putty and light body (PL). Dies obtained were evaluated with a travelling microscope to measure the buccolingual width of the tooth at the margin by using the sharp corners of the notches as reference points. Statistical Analysis Used: Descriptive analysis namely mean and standard deviation, one-way analysis of variance test. Results: The results obtained in this study indicate that though not statistically significant, the metal dual arch trays performed better when compared to the plastic trays in reproducing die dimensions. Conclusions: From the results obtained, dies poured from combination of heavy body and light body impressions using plastic or metal dual arch trays showed least variation in bucco-lingual dimension from master model. PMID:27141172
NASA Astrophysics Data System (ADS)
Hu, X.; Zhan, L.; Xia, Y.
2009-03-01
A novel optical filter based on enhanced transmission through metallic nano-slit is proposed for dual-wavelength fluorescence-spectrometry. A special structure, sampled-period slit array, is utilized to meet the requirement of dual-wavelength transmission in this system. Structure parameters on the transmission property are analyzed by means of Fourier transformation. With the features both to enhance the fluorescence generation and to enhance light transmission, in addition with the feasibility for miniaturization, integration on one chip, and mass production, the proposed filters are promising for the realization of dual-wavelength fluorescence-spectrometry in micro-total-analysis-system.
Dual-modality imaging of function and physiology
NASA Astrophysics Data System (ADS)
Hasegawa, Bruce H.; Iwata, Koji; Wong, Kenneth H.; Wu, Max C.; Da Silva, Angela; Tang, Hamilton R.; Barber, William C.; Hwang, Andrew B.; Sakdinawat, Anne E.
2002-04-01
Dual-modality imaging is a technique where computed tomography or magnetic resonance imaging is combined with positron emission tomography or single-photon computed tomography to acquire structural and functional images with an integrated system. The data are acquired during a single procedure with the patient on a table viewed by both detectors to facilitate correlation between the structural and function images. The resulting data can be useful for localization for more specific diagnosis of disease. In addition, the anatomical information can be used to compensate the correlated radionuclide data for physical perturbations such as photon attenuation, scatter radiation, and partial volume errors. Thus, dual-modality imaging provides a priori information that can be used to improve both the visual quality and the quantitative accuracy of the radionuclide images. Dual-modality imaging systems also are being developed for biological research that involves small animals. The small-animal dual-modality systems offer advantages for measurements that currently are performed invasively using autoradiography and tissue sampling. By acquiring the required data noninvasively, dual-modality imaging has the potential to allow serial studies in a single animal, to perform measurements with fewer animals, and to improve the statistical quality of the data.
NASA Technical Reports Server (NTRS)
Johnson, Paul K.
2007-01-01
NASA Glenn Research Center (GRC) contracted Barber-Nichols, Arvada, CO to construct a dual Brayton power conversion system for use as a hardware proof of concept and to validate results from a computational code known as the Closed Cycle System Simulation (CCSS). Initial checkout tests were performed at Barber- Nichols to ready the system for delivery to GRC. This presentation describes the system hardware components and lists the types of checkout tests performed along with a couple issues encountered while conducting the tests. A description of the CCSS model is also presented. The checkout tests did not focus on generating data, therefore, no test data or model analyses are presented.
Compact wearable dual-mode imaging system for real-time fluorescence image-guided surgery
Zhu, Nan; Huang, Chih-Yu; Mondal, Suman; Gao, Shengkui; Huang, Chongyuan; Gruev, Viktor; Achilefu, Samuel; Liang, Rongguang
2015-01-01
Abstract. A wearable all-plastic imaging system for real-time fluorescence image-guided surgery is presented. The compact size of the system is especially suitable for applications in the operating room. The system consists of a dual-mode imaging system, see-through goggle, autofocusing, and auto-contrast tuning modules. The paper will discuss the system design and demonstrate the system performance. PMID:26358823
Parallel Algorithms for Computational Models of Geophysical Systems
NASA Astrophysics Data System (ADS)
Carrillo Ledesma, A.; Herrera, I.; de la Cruz, L. M.; Hernández, G.; Grupo de Modelacion Matematica y Computacional
2013-05-01
Mathematical models of many systems of interest, including very important continuous systems of Earth Sciences and Engineering, lead to a great variety of partial differential equations (PDEs) whose solution methods are based on the computational processing of large-scale algebraic systems. Furthermore, the incredible expansion experienced by the existing computational hardware and software has made amenable to effective treatment problems of an ever increasing diversity and complexity, posed by scientific and engineering applications. Parallel computing is outstanding among the new computational tools and, in order to effectively use the most advanced computers available today, massively parallel software is required. Domain decomposition methods (DDMs) have been developed precisely for effectively treating PDEs in paralle. Ideally, the main objective of domain decomposition research is to produce algorithms capable of 'obtaining the global solution by exclusively solving local problems', but up-to-now this has only been an aspiration; that is, a strong desire for achieving such a property and so we call it 'the DDM-paradigm'. In recent times, numerically competitive DDM-algorithms are non-overlapping, preconditioned and necessarily incorporate constraints which pose an additional challenge for achieving the DDM-paradigm. Recently a group of four algorithms, referred to as the 'DVS-algorithms', which fulfill the DDM-paradigm, was developed. To derive them a new discretization method, which uses a non-overlapping system of nodes (the derived-nodes), was introduced. This discretization procedure can be applied to any boundary-value problem, or system of such equations. In turn, the resulting system of discrete equations can be treated using any available DDM-algorithm. In particular, two of the four DVS-algorithms mentioned above were obtained by application of the well-known and very effective algorithms BDDC and FETI-DP; these will be referred to as the DVS-BDDC and DVS-FETI-DP algorithms. The other two, which will be referred to as the DVS-PRIMAL and DVS-DUAL algorithms, were obtained by application of two new algorithms that had not been previously reported in the literature. As said before, the four DVS-algorithms constitute a group of preconditioned and constrained algorithms that, for the first time, fulfill the DDM-paradigm. Both, BDDC and FETI-DP, are very well-known; and both are highly efficient. Recently, it was established that these two methods are closely related and its numerical performance is quite similar. On the other hand, through numerical experiments, we have established that the numerical performances of each one of the members of DVS-algorithms group (DVS-BDDC, DVS-FETI-DP, DVS-PRIMAL and DVS-DUAL) are very similar too. Furthermore, we have carried out comparisons of the performances of the standard versions of BDDC and FETI-DP with DVS-BDDC and DVS-FETI-DP, and in all such numerical experiments the DVS algorithms have performed significantly better.
Dimai, Hans P
2017-11-01
Dual-energy X-ray absorptiometry (DXA) is a two-dimensional imaging technology developed to assess bone mineral density (BMD) of the entire human skeleton and also specifically of skeletal sites known to be most vulnerable to fracture. In order to simplify interpretation of BMD measurement results and allow comparability among different DXA-devices, the T-score concept was introduced. This concept involves an individual's BMD which is then compared with the mean value of a young healthy reference population, with the difference expressed as a standard deviation (SD). Since the early nineties of the past century, the diagnostic categories "normal, osteopenia, and osteoporosis", as recommended by a WHO working Group, are based on this concept. Thus, DXA is still the globally accepted "gold-standard" method for the noninvasive diagnosis of osteoporosis. Another score obtained from DXA measurement, termed Z-score, describes the number of SDs by which the BMD in an individual differs from the mean value expected for age and sex. Although not intended for diagnosis of osteoporosis in adults, it nevertheless provides information about an individual's fracture risk compared to peers. DXA measurement can either be used as a "stand-alone" means in the assessment of an individual's fracture risk, or incorporated into one of the available fracture risk assessment tools such as FRAX® or Garvan, thus improving the predictive power of such tools. The issue which reference databases should be used by DXA-device manufacturers for T-score reference standards has been recently addressed by an expert group, who recommended use National Health and Nutrition Examination Survey III (NHANES III) databases for the hip reference standard but own databases for the lumbar spine. Furthermore, in men it is recommended use female reference databases for calculation of the T-score and use male reference databases for calculation of Z-score. Copyright © 2017 Elsevier Inc. All rights reserved.
Availability Analysis of Dual Mode Systems
DOT National Transportation Integrated Search
1974-04-01
The analytical procedures presented define a method of evaluating the effects of failures in a complex dual-mode system based on a worst case steady-state analysis. The computed result is an availability figure of merit and not an absolute prediction...
77 FR 19175 - Atlantic Highly Migratory Species; 2012 Atlantic Bluefin Tuna Quota Specifications
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-30
...-XA920 Atlantic Highly Migratory Species; 2012 Atlantic Bluefin Tuna Quota Specifications AGENCY... INFORMATION: Atlantic bluefin tuna, bigeye tuna, albacore tuna, yellowfin tuna, and skipjack tuna (hereafter referred to as ``Atlantic tunas'') are managed under the dual authority of the Magnuson-Stevens Fishery...
Reference Determinant Dependence of the Random Phase Approximation in 3d Transition Metal Chemistry.
Bates, J E; Mezei, P D; Csonka, G I; Sun, J; Ruzsinszky, A
2017-01-10
Without extensive fitting, accurate prediction of transition metal chemistry is a challenge for semilocal and hybrid density funcitonals. The Random Phase Approximation (RPA) has been shown to yield superior results to semilocal functionals for main group thermochemistry, but much less is known about its performance for transition metals. We have therefore analyzed the behavior of reaction energies, barrier heights, and ligand dissociation energies obtained with RPA and compare our results to several semilocal and hybrid functionals. Particular attention is paid to the reference determinant dependence of RPA. We find that typically the results do not vary much between semilocal or hybrid functionals as a reference, as long as the fraction of exact exchange (EXX) mixing in the hybrid functional is small. For large fractions of EXX mixing, however, the Hartree-Fock-like nature of the determinant can severely degrade the performance. Overall, RPA systematically reduces the errors of semilocal functionals and delivers excellent performance from a single reference determinant for inherently multireference reactions. The behavior of dual hybrids that combine RPA correlation with a hybrid exchange energy was also explored, but ultimately did not lead to a systematic improvement compared to traditional RPA for these systems. We rationalize this conclusion by decomposing the contributions to the reaction energies, and briefly discuss the possible implications for double-hybrid functionals based on RPA. The correlation between EXX mixing and spin-symmetry breaking is also discussed.
46 CFR 183.324 - Dual voltage generators.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 7 2013-10-01 2013-10-01 false Dual voltage generators. 183.324 Section 183.324 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.324 Dual voltage generators...
46 CFR 183.324 - Dual voltage generators.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 7 2011-10-01 2011-10-01 false Dual voltage generators. 183.324 Section 183.324 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.324 Dual voltage generators...
46 CFR 183.324 - Dual voltage generators.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 7 2014-10-01 2014-10-01 false Dual voltage generators. 183.324 Section 183.324 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.324 Dual voltage generators...
46 CFR 183.324 - Dual voltage generators.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 7 2012-10-01 2012-10-01 false Dual voltage generators. 183.324 Section 183.324 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION Power Sources and Distribution Systems § 183.324 Dual voltage generators...
ERIC Educational Resources Information Center
Stephenson, Lisa G.
2013-01-01
Credit-based transition programs provide high school students with opportunities to jump start their college education. The Kentucky Community and Technical College System (KCTCS) offers college credit through dual-credit programs. While KCTCS dual-credit offerings have been successful in helping high school students start their college education…
Dual-spin attitude control for outer planet missions
NASA Technical Reports Server (NTRS)
Ward, R. S.; Tauke, G. J.
1977-01-01
The applicability of dual-spin technology to a Jupiter orbiter with probe mission was investigated. Basic mission and system level attitude control requirements were established and preliminary mechanization and control concepts developed. A comprehensive 18-degree-of-freedom digital simulation was utilized extensively to establish control laws, study dynamic interactions, and determined key sensitivities. Fundamental system/subsystem constraints were identified, and the applicability of dual-spin technology to a Jupiter orbiter with probe mission was validated.
Nonlocal symmetries and Bäcklund transformations for the self-dual Yang-Mills system
NASA Astrophysics Data System (ADS)
Papachristou, C. J.; Harrison, B. Kent
1988-01-01
The observation is made that generalized evolutionary isovectors of the self-dual Yang-Mills equation, obtained by ``verticalization'' of the geometrical isovectors derived in a previous paper [J. Math. Phys. 28, 1261 (1987)], generate Bäcklund transformations for the self-dual system. In particular, new Bäcklund transformations are obtained by ``verticalizing'' the generators of point transformations on the solution manifold. A geometric ansatz for the derivation of such (generally nonlocal) symmetries is proposed.
On the manipulability of dual cooperative robots
NASA Technical Reports Server (NTRS)
Chiacchio, P.; Chiaverini, S.; Sciavicco, L.; Siciliano, B.
1989-01-01
The definition of manipulability ellipsoids for dual robot systems is given. A suitable kineto-static formulation for dual cooperative robots is adopted which allows for a global task space description of external and internal forces, and relative velocities. The well known concepts of force and velocity manipulability ellipsoids for a single robot are formally extended and the contributions of the two single robots to the cooperative system ellipsoids are illustrated. Duality properties are discussed. A practical case study is developed.
Intelligent fault diagnosis and failure management of flight control actuation systems
NASA Technical Reports Server (NTRS)
Bonnice, William F.; Baker, Walter
1988-01-01
The real-time fault diagnosis and failure management (FDFM) of current operational and experimental dual tandem aircraft flight control system actuators was investigated. Dual tandem actuators were studied because of the active FDFM capability required to manage the redundancy of these actuators. The FDFM methods used on current dual tandem actuators were determined by examining six specific actuators. The FDFM capability on these six actuators was also evaluated. One approach for improving the FDFM capability on dual tandem actuators may be through the application of artificial intelligence (AI) technology. Existing AI approaches and applications of FDFM were examined and evaluated. Based on the general survey of AI FDFM approaches, the potential role of AI technology for real-time actuator FDFM was determined. Finally, FDFM and maintainability improvements for dual tandem actuators were recommended.
[The Yin and Yang movement in the cosmology of Chinese medicine].
Coutinho, Bernardo Diniz; Dulcetti, Pérola Goretti Sichero
2015-01-01
After being developed in the East, based on Taoist cosmology, Chinese medicine has been practiced in the West based on scientific foundations and biomedical paradigms. Some traditional elements of this philosophy were abandoned, such as the theory of Yin and Yang, knowledge that is essential for understanding the health-disease process resulting from the circulation of the body's energy flow. This article studies the movement of the dual elements of Yin and Yang in Chinese medical teaching, seeking to understand how this line of thought developed and how it has contributed towards establishing a system of diagnosis and therapy. The methodology employed was to analyze literature on the subject, based on theoretical references to Taoist thought and traditional Chinese medicine.
What Contributes to the (Im)Balanced Division of Family Work Between the Sexes?
Lothaller, Harald; Mikula, Gerold; Schoebi, Dominik
2011-01-01
This study examines a comprehensive set of variables that have been proposed as explaining the imbalance of the division of family work between the sexes. The analyses use survey data of 735 dual-earner couples from Austria, the Netherlands, and Portugal. The results support theoretical explanations referring to time availability, gender ideology, relative resources, and the importance of characteristics of the family system. No support was obtained for the doing-gender perspective. Additional findings suggest that increased consideration of psychological concepts adds to the understanding of why women do more family work than men. The analyses revealed similarities, but also differences between the factors that contribute to the division of household labor and childcare. PMID:22318972
Preliminary results from BCG and ECG measurements in the heart failure clinic.
Giovangrandi, Laurent; Inan, Omer T; Banerjee, Dipanjan; Kovacs, Gregory T A
2012-01-01
We report on the preliminary deployment of a bathroom scale-based ballistocardiogram (BCG) system for the in-hospital monitoring of patients with heart failure. These early trials provided valuable insights into the challenges and opportunities for such monitoring. In particular, the need for robust algorithms and adapted BCG metric is suggested. The system was designed to be robust and user-friendly, with dual ballistocardiogram (BCG) and electrocardiogram (ECG) capabilities. The BCG was measured from a modified bathroom scale, while the ECG (used as timing reference) was measured using dry handlebar electrodes. The signal conditioning and digitization circuits were USB-powered, and data acquisition performed using a netbook. Four patients with a NYHA class III at admission were measured daily for the duration of their treatment at Stanford hospital. A measure of BCG quality, in essence a quantitative implementation of the BCG classes originally defined in the 1950s, is proposed as a practical parameter.
Liu, Hongliang; Li, Yingying; Sun, Kang; Fan, Junbing; Zhang, Pengchao; Meng, Jingxin; Wang, Shutao; Jiang, Lei
2013-05-22
Artificial stimuli-responsive surfaces that can mimic the dynamic function of living systems have attracted much attention. However, there exist few artificial systems capable of responding to dual- or multistimulation as the natural system does. Herein, we synthesize a pH and glucose dual-responsive surface by grafting poly(acrylamidophenylboronic acid) (polyAAPBA) brush from aligned silicon nanowire (SiNW) array. The as-prepared surface can reversibly capture and release targeted cancer cells by precisely controlling pH and glucose concentration, exhibiting dual-responsive AND logic. In the presence of 70 mM glucose, the surface is pH responsive, which can vary from a cell-adhesive state to a cell-repulsive state by changing the pH from 6.8 to 7.8. While keeping the pH at 7.8, the surface becomes glucose responsive--capturing cells in the absence of glucose and releasing cells by adding 70 mM glucose. Through simultaneously changing the pH and glucose concentration from pH 6.8/0 mM glucose to pH 7.8/70 mM glucose, the surface is dual responsive with the capability to switch between cell capture and release for at least 5 cycles. The cell capture and release process on this dual-responsive surface is noninvasive with cell viability higher than 95%. Moreover, topographical interaction between the aligned SiNW array and cell protrusions greatly amplifies the responsiveness and accelerates the response rate of the dual-responsive surface between cell capture and release. The responsive mechanism of the dual-responsive surface is systematically studied using a quartz crystal microbalance, which shows that the competitive binding between polyAAPBA/sialic acid and polyAAPBA/glucose contributes to the dual response. Such dual-responsive surface can significantly impact biomedical and biological applications including cell-based diagnostics, in vivo drug delivery, etc.
Li, Na; Takagaki, Tomohiro; Sadr, Alireza; Waidyasekera, Kanchana; Ikeda, Masaomi; Chen, Jihua; Nikaido, Toru; Tagami, Junji
2011-12-01
To evaluate the microtensile bond strength (μTBS) and acid-base resistant zone (ABRZ) of two dualcuring core systems to dentin using four curing modes. Sixty-four caries-free human molars were randomly divided into two groups according to two dual-curing resin core systems: (1) Clearfil DC Core Automix; (2) Estelite Core Quick. For each core system, four different curing modes were applied to the adhesive and core resin: (1) dual-cured and dual-cured (DD); (2) chemically cured and dual-cured (CD); (3) dual-cured and chemically cured (DC); (4) chemically cured and chemically cured (CC). The specimens were sectioned into sticks (n = 20 for each group) for the microtensile bond test. μTBS data were analyzed using two-way ANOVA and the Dunnett T3 test. Failure patterns were examined with scanning electron microscopy (SEM) to determine the proportion of each mode. Dentin sandwiches were produced and subjected to an acid-base challenge. After argon-ion etching, the ultrastructure of ABRZ was observed using SEM. For Clearfil DC Core Automix, the μTBS values in MPa were as follows: DD: 29.1 ± 5.4, CD: 21.6 ± 5.6, DC: 17.9 ± 2.8, CC: 11.5 ± 3.2. For Estelite Core Quick, they were: DD: 48.9 ±5.7, CD: 20.5 ± 4.7, DC: 41.4 ± 8.3, CC: 19.1 ± 6.0. The bond strength was affected by both material and curing mode, and the interaction of the two factors was significant (p < 0.001). Within both systems, there were significant differences among groups, and the DD group showed the highest μTBS (p < 0.05). ABRZ morphology was not affected by curing mode, but it was highly adhesive-material dependent. The curing mode of dual-curing core systems affects bond strength to dentin, but has no significant effect on the formation of ABRZ.
The dilemma of dual use biological research: Polish perspective.
Czarkowski, Marek
2010-03-01
Biological research with legitimate scientific purpose that may be misused to pose a biological threat to public health and/or national security is termed dual use. In Poland there are adequate conditions for conducting experiments that could be qualified as dual use research, and therefore, a risk of attack on Poland or other countries exists. Optimal solutions for limiting such threats are required, and the national system of biosecurity should enable early, reliable, and complete identification of this type of research. Scientists should have a fundamental role in this process, their duty being to immediately, upon identification, report research with dual use potential. An important entity in the identification system of dual use research should also be the Central Register of Biological and Biomedical Research, which gathers information about all biological and biomedical research being conducted in a given country. Publishers, editors, and review committees of journals and other scientific publications should be involved in evaluating results of clinical trials. The National Council of Biosecurity should be the governmental institution responsible for developing a system of dual use research threat prevention. Its role would be to develop codes of conduct, form counsel of expertise, and monitor the problem at national level, while the Dual Use Research Committee would be responsible for individual cases. In Poland, current actions aiming to provide biological safety were based on developing and passing an act about genetically modified organisms (GMO's) and creating a GMO Committee. Considering experiences of other nations, one should view these actions as fragmentary, and thus insufficient protection against dual use research threats.
ERIC Educational Resources Information Center
Hongzhi, Long
2017-01-01
Dual-language education models are theoretical and practical systems formed through the process of dual-language education and centered on study and teaching. The language environment is the basis for developing and reforming dual-language education models. The author takes Xiahe County in Gannan Tibetan Autonomous Prefecture as an example and…
Control Activity in Support of NASA Turbine Based Combined Cycle (TBCC) Research
NASA Technical Reports Server (NTRS)
Stueber, Thomas J.; Vrnak, Daniel R.; Le, Dzu K.; Ouzts, Peter J.
2010-01-01
Control research for a Turbine Based Combined Cycle (TBCC) propulsion system is the current focus of the Hypersonic Guidance, Navigation, and Control (GN&C) discipline team. The ongoing work at the NASA Glenn Research Center (GRC) supports the Hypersonic GN&C effort in developing tools to aid the design of control algorithms to manage a TBCC airbreathing propulsion system during a critical operating period. The critical operating period being addressed in this paper is the span when the propulsion system transitions from one cycle to another, referred to as mode transition. One such tool, that is a basic need for control system design activities, is computational models (hereto forth referred to as models) of the propulsion system. The models of interest for designing and testing controllers are Control Development Models (CDMs) and Control Validation Models (CVMs). CDMs and CVMs are needed for each of the following propulsion system elements: inlet, turbine engine, ram/scram dual-mode combustor, and nozzle. This paper presents an overall architecture for a TBCC propulsion system model that includes all of the propulsion system elements. Efforts are under way, focusing on one of the propulsion system elements, to develop CDMs and CVMs for a TBCC propulsion system inlet. The TBCC inlet aerodynamic design being modeled is that of the Combined-Cycle Engine (CCE) Testbed. The CCE Testbed is a large-scale model of an aerodynamic design that was verified in a small-scale screening experiment. The modeling approach includes employing existing state-of-the-art simulation codes, developing new dynamic simulations, and performing system identification experiments on the hardware in the NASA GRC 10 by10-Foot Supersonic Wind Tunnel. The developed CDMs and CVMs will be available for control studies prior to hardware buildup. The system identification experiments on the CCE Testbed will characterize the necessary dynamics to be represented in CDMs for control design. These system identification models will also be the reference models to validate the CDM and CVM models. Validated models will give value to the tools used to develop the models.
Special Education Teacher Preparation in Singapore's Dual Education System
ERIC Educational Resources Information Center
Walker, Zachary
2016-01-01
Global comparisons of teacher education programs should start with an understanding of the school systems that teachers are being prepared for in their local contexts. The purpose of this article is to describe Singapore's dual education system as well as teacher preparation in a country that educates many students with disabilities in a separate…
NASA Astrophysics Data System (ADS)
Cho, M.; Lim, K.-t.; Kim, H.; Yeom, J.-y.; Kim, J.; Lee, C.; Choi, H.; Cho, G.
2017-01-01
In most cases, a PET system has numerous electrical components and channel circuits and thus it would rather be a bulky product. Also, most existing systems receive analog signals from detectors which make them vulnerable to signal distortions. For these reasons, channel reduction techniques are important. In this work, an ASIC for PET module is being proposed. An ASIC chip for 16 PET detector channels, VSSPDC, has been designed and simulated. The main function of the chip is 16-to-1 channel reduction, i.e., finding the position of only the valid signals, signal timing, and magnitudes in all 16 channels at every recorded event. The ASIC comprises four of 4-channel modules and a 2nd 4-to-1 router. A single channel module comprises a transimpedance amplifier for the silicon photomultipliers, dual comparators with high and low level references, and a logic circuitry. While the high level reference was used to test the validity of the signal, the low level reference was used for the timing. The 1-channel module of the ASIC produced an energy pulse by time-over-threshold method and it also produced a time pulse with a fixed delayed time. Since the ASIC chip outputs only a few digital pulses and does not require an external clock, it has an advantage over noise properties. The cadence simulation showed the good performance of the chip as designed.
Di Fusco, Massimo; Federico, Rodolfo; Boffi, Alberto; Macone, Alberto; Favero, Gabriele; Mazzei, Franco
2011-08-01
In this work, we have characterized a diamine oxidase (DAO) from Lathyrus sativus and evaluated its use, for the first time, as biocatalytic component of an electrochemical biosensor for the determination of biogenic amines index in wine and beer samples. Firstly, DAO was electrokinetically characterized free in solution by means of a platinum electrode and then immobilized by using polyazetidine prepolimer on the surface of screen-printed electrodes constituted of two gold working electrodes. The amperometric measurements were carried out by using a flow system at a fixed potential of +600 mV vs the internal silver pseudo reference in phosphate buffer solution (0.1 mol l(-1), pH = 7.4). The analysis of wine and beer samples were performed in flow injection system using the dual channel transducer providing simultaneous detection of sample and blank signal, and the resulting signal (after subtraction of the blank signal) was referred to that of putrescine. The results were compared with those obtained using a modified reference method based on gas chromatography-mass spectrometry analysis on the same samples. The results obtained in the analysis of Italian wines shows the better suitability of DAO-based biosensor in the determination of the biogenic amines (BAs) index expressed as putrescine equivalent in both red and white wines, being less efficient in beer samples where it underestimates by about 50% the BAs content.
Dual PECCS: a cognitive system for conceptual representation and categorization
NASA Astrophysics Data System (ADS)
Lieto, Antonio; Radicioni, Daniele P.; Rho, Valentina
2017-03-01
In this article we present an advanced version of Dual-PECCS, a cognitively-inspired knowledge representation and reasoning system aimed at extending the capabilities of artificial systems in conceptual categorization tasks. It combines different sorts of common-sense categorization (prototypical and exemplars-based categorization) with standard monotonic categorization procedures. These different types of inferential procedures are reconciled according to the tenets coming from the dual process theory of reasoning. On the other hand, from a representational perspective, the system relies on the hypothesis of conceptual structures represented as heterogeneous proxytypes. Dual-PECCS has been experimentally assessed in a task of conceptual categorization where a target concept illustrated by a simple common-sense linguistic description had to be identified by resorting to a mix of categorization strategies, and its output has been compared to human responses. The obtained results suggest that our approach can be beneficial to improve the representational and reasoning conceptual capabilities of standard cognitive artificial systems, and - in addition - that it may be plausibly applied to different general computational models of cognition. The current version of the system, in fact, extends our previous work, in that Dual- PECCS is now integrated and tested into two cognitive architectures, ACT-R and CLARION, implementing different assumptions on the underlying invariant structures governing human cognition. Such integration allowed us to extend our previous evaluation.
Active-passive hybrid piezoelectric actuators for high-precision hard disk drive servo systems
NASA Astrophysics Data System (ADS)
Chan, Kwong Wah; Liao, Wei-Hsin
2006-03-01
Positioning precision is crucial to today's increasingly high-speed, high-capacity, high data density, and miniaturized hard disk drives (HDDs). The demand for higher bandwidth servo systems that can quickly and precisely position the read/write head on a high track density becomes more pressing. Recently, the idea of applying dual-stage actuators to track servo systems has been studied. The push-pull piezoelectric actuated devices have been developed as micro actuators for fine and fast positioning, while the voice coil motor functions as a large but coarse seeking. However, the current dual-stage actuator design uses piezoelectric patches only without passive damping. In this paper, we propose a dual-stage servo system using enhanced active-passive hybrid piezoelectric actuators. The proposed actuators will improve the existing dual-stage actuators for higher precision and shock resistance, due to the incorporation of passive damping in the design. We aim to develop this hybrid servo system not only to increase speed of track seeking but also to improve precision of track following servos in HDDs. New piezoelectrically actuated suspensions with passive damping have been designed and fabricated. In order to evaluate positioning and track following performances for the dual-stage track servo systems, experimental efforts are carried out to implement the synthesized active-passive suspension structure with enhanced piezoelectric actuators using a composite nonlinear feedback controller.
Design of a dual-band radiation system for a complex magnetically insulated line oscillator
NASA Astrophysics Data System (ADS)
Yu, Yuanqiang; Wang, Xiaoyu; Fan, Yuwei; Li, Ankun; Li, Sirui
2018-05-01
In this paper, a dual-band radiation system for a complex magnetically insulated line oscillator (MILO) is designed and investigated numerically. The radiation system comprises a coaxial plate-inserted mode converter, a power combiner and a conical horn antenna. The mode converter converts the coaxial TEM mode microwaves (1.775 GHz and 3.175 GHz) which are generated by the complex MILO into the coaxial TE11 mode microwaves, and then the coaxial TE11 mode microwaves are combined by the power combiner in a circular waveguide. Lastly, the microwaves are radiated by a conical horn antenna into the air. The gains of the dual-band radiation system are calculated to be 17.8 dB at 1.775 GHz and 18.9 dB at 3.175 GHz. The 3 dB beam widths are 20.5° in E-plane, 26.4° in H-plane at 1.775 GHz and 20.8° in E-plane, 15.1° in H-plane at 3.175 GHz. The power transmission efficiencies of the dual-band radiation system are 98.5% at 1.775 GHz and 95.7% at 3.175 GHz respectively. The power handling capacities of the dual-band radiation system are 4.2 GW at 1.775 GHz and 4.7 GW at 3.175 GHz, respectively.
Dual-mode ultraflow access networks: a hybrid solution for the access bottleneck
NASA Astrophysics Data System (ADS)
Kazovsky, Leonid G.; Shen, Thomas Shunrong; Dhaini, Ahmad R.; Yin, Shuang; De Leenheer, Marc; Detwiler, Benjamin A.
2013-12-01
Optical Flow Switching (OFS) is a promising solution for large Internet data transfers. In this paper, we introduce UltraFlow Access, a novel optical access network architecture that offers dual-mode service to its end-users: IP and OFS. With UltraFlow Access, we design and implement a new dual-mode control plane and a new dual-mode network stack to ensure efficient connection setup and reliable and optimal data transmission. We study the impact of the UltraFlow system's design on the network throughput. Our experimental results show that with an optimized system design, near optimal (around 10 Gb/s) OFS data throughput can be attained when the line rate is 10Gb/s.
NASA Technical Reports Server (NTRS)
Kobayashi, Takahisa; Simon, Donald L.
2008-01-01
In this paper, a baseline system which utilizes dual-channel sensor measurements for aircraft engine on-line diagnostics is developed. This system is composed of a linear on-board engine model (LOBEM) and fault detection and isolation (FDI) logic. The LOBEM provides the analytical third channel against which the dual-channel measurements are compared. When the discrepancy among the triplex channels exceeds a tolerance level, the FDI logic determines the cause of the discrepancy. Through this approach, the baseline system achieves the following objectives: (1) anomaly detection, (2) component fault detection, and (3) sensor fault detection and isolation. The performance of the baseline system is evaluated in a simulation environment using faults in sensors and components.
NASA Astrophysics Data System (ADS)
Lefebvre, Joël.; Castonguay, Alexandre; Lesage, Frédéric
2018-02-01
High resolution imaging of whole rodent brains using serial OCT scanners is a promising method to investigate microstructural changes in tissue related to the evolution of neuropathologies. Although micron to sub-micron sampling resolution can be obtained by using high numerical aperture objectives and dynamic focusing, such an imaging system is not adapted to whole brain imaging. This is due to the large amount of data it generates and the significant computational resources required for reconstructing such volumes. To address this limitation, a dual resolution serial OCT scanner was developed. The optical setup consists in a swept-source OCT made of two sample and reference arms, each arm being coupled with different microscope objectives (3X / 40X). Motorized flip mirrors were used to switch between each OCT arm, thus allowing low and high resolution acquisitions within the same sample. The low resolution OCT volumes acquired with the 3X arm were stitched together, providing a 3D map of the whole mouse brain. This brain can be registered to an OCT brain template to enable neurological structures localization. The high resolution volumes acquired with the 40X arm were also stitched together to create local high resolution 3D maps of the tissue microstructure. The 40X data can be acquired at any arbitrary location in the sample, thus limiting storage-heavy high resolution data to application restricted to specific regions of interest. By providing dual-resolution OCT data, this setup can be used to validate diffusion MRI with tissue microstructure derived metrics measured at any location in ex vivo brains.
Does It Really Matter Where You Look When Walking on Stairs? Insights from a Dual-Task Study
Miyasike-daSilva, Veronica; McIlroy, William E.
2012-01-01
Although the visual system is known to provide relevant information to guide stair locomotion, there is less understanding of the specific contributions of foveal and peripheral visual field information. The present study investigated the specific role of foveal vision during stair locomotion and ground-stairs transitions by using a dual-task paradigm to influence the ability to rely on foveal vision. Fifteen healthy adults (26.9±3.3 years; 8 females) ascended a 7-step staircase under four conditions: no secondary tasks (CONTROL); gaze fixation on a fixed target located at the end of the pathway (TARGET); visual reaction time task (VRT); and auditory reaction time task (ART). Gaze fixations towards stair features were significantly reduced in TARGET and VRT compared to CONTROL and ART. Despite the reduced fixations, participants were able to successfully ascend stairs and rarely used the handrail. Step time was increased during VRT compared to CONTROL in most stair steps. Navigating on the transition steps did not require more gaze fixations than the middle steps. However, reaction time tended to increase during locomotion on transitions suggesting additional executive demands during this phase. These findings suggest that foveal vision may not be an essential source of visual information regarding stair features to guide stair walking, despite the unique control challenges at transition phases as highlighted by phase-specific challenges in dual-tasking. Instead, the tendency to look at the steps in usual conditions likely provides a stable reference frame for extraction of visual information regarding step features from the entire visual field. PMID:22970297
A low-power current-reuse dual-band analog front-end for multi-channel neural signal recording.
Sepehrian, H; Gosselin, B
2014-01-01
Thoroughly studying the brain activity of freely moving subjects requires miniature data acquisition systems to measure and wirelessly transmit neural signals in real time. In this application, it is mandatory to simultaneously record the bioelectrical activity of a large number of neurons to gain a better knowledge of brain functions. However, due to limitations in transferring the entire raw data to a remote base station, employing dedicated data reduction techniques to extract the relevant part of neural signals is critical to decrease the amount of data to transfer. In this work, we present a new dual-band neural amplifier to separate the neuronal spike signals (SPK) and the local field potential (LFP) simultaneously in the analog domain, immediately after the pre-amplification stage. By separating these two bands right after the pre-amplification stage, it is possible to process LFP and SPK separately. As a result, the required dynamic range of the entire channel, which is determined by the signal-to-noise ratio of the SPK signal of larger bandwidth, can be relaxed. In this design, a new current-reuse low-power low-noise amplifier and a new dual-band filter that separates SPK and LFP while saving capacitors and pseudo resistors. A four-channel dual-band (SPK, LFP) analog front-end capable of simultaneously separating SPK and LFP is implemented in a TSMC 0.18 μm technology. Simulation results present a total power consumption per channel of 3.1 μw for an input referred noise of 3.28 μV and a NEF for 2.07. The cutoff frequency of the LFP band is fc=280 Hz, and fL=725 Hz and fL=11.2 KHz for SPK, with 36 dB gain for LFP band 46 dB gain for SPK band.
NASA Astrophysics Data System (ADS)
Gu, Defeng; Liu, Ye; Yi, Bin; Cao, Jianfeng; Li, Xie
2017-12-01
An experimental satellite mission termed atmospheric density detection and precise orbit determination (APOD) was developed by China and launched on 20 September 2015. The micro-electro-mechanical system (MEMS) GPS receiver provides the basis for precise orbit determination (POD) within the range of a few decimetres. The in-flight performance of the MEMS GPS receiver was assessed. The average number of tracked GPS satellites is 10.7. However, only 5.1 GPS satellites are available for dual-frequency navigation because of the loss of many L2 observations at low elevations. The variations in the multipath error for C1 and P2 were estimated, and the maximum multipath error could reach up to 0.8 m. The average code noises are 0.28 m (C1) and 0.69 m (P2). Using the MEMS GPS receiver, the orbit of the APOD nanosatellite (APOD-A) was precisely determined. Two types of orbit solutions are proposed: a dual-frequency solution and a single-frequency solution. The antenna phase center variations (PCVs) and code residual variations (CRVs) were estimated, and the maximum value of the PCVs is 4.0 cm. After correcting the antenna PCVs and CRVs, the final orbit precision for the dual-frequency and single-frequency solutions were 7.71 cm and 12.91 cm, respectively, validated using the satellite laser ranging (SLR) data, which were significantly improved by 3.35 cm and 25.25 cm. The average RMS of the 6-h overlap differences in the dual-frequency solution between two consecutive days in three dimensions (3D) is 4.59 cm. The MEMS GPS receiver is the Chinese indigenous onboard receiver, which was successfully used in the POD of a nanosatellite. This study has important reference value for improving the MEMS GPS receiver and its application in other low Earth orbit (LEO) nanosatellites.
Dual resonant frequencies effects on an induction-based oil palm fruit sensor.
Harun, Noor Hasmiza; Misron, Norhisam; Mohd Sidek, Roslina; Aris, Ishak; Wakiwaka, Hiroyuki; Tashiro, Kunihisa
2014-11-19
As the main exporter in the oil palm industry, the need to improve the quality of palm oil has become the main interest among all the palm oil millers in Malaysia. To produce good quality palm oil, it is important for the miller to harvest a good oil palm Fresh Fruit Bunch (FFB). Conventionally, the main reference used by Malaysian harvesters is the manual grading standard published by the Malaysian Palm Oil Board (MPOB). A good oil palm FFB consists of all matured fruitlets, aged between 18 to 21 weeks of antheses (WAA). To expedite the harvesting process, it is crucial to implement an automated detection system for determining the maturity of the oil palm FFB. Various automated detection methods have been proposed by researchers in the field to replace the conventional method. In our preliminary study, a novel oil palm fruit sensor to detect the maturity of oil palm fruit bunch was proposed. The design of the proposed air coil sensor based on the inductive sensor was further investigated mainly in the context of the effect of coil diameter to improve its sensitivity. In this paper, the sensitivity of the inductive sensor was further examined with a dual flat-type shape of air coil. The dual air coils were tested on fifteen samples of fruitlet from two categories, namely ripe and unripe. Samples were tested within 20 Hz to 10 MHz while evaluations on both peaks were done separately before the gap between peaks was analyzed. A comparative analysis was conducted to investigate the improvement in sensitivity of the induction-based oil palm fruit sensor as compared to previous works. Results from the comparative study proved that the inductive sensor using a dual flat-type shape air coil has improved by up to 167%. This provides an indication in the improvement in the coil sensitivity of the palm oil fruit sensor based on the induction concept.
Reddy, T; McLaughlin, P D; Mallinson, P I; Reagan, A C; Munk, P L; Nicolaou, S; Ouellette, H A
2015-02-01
The purpose of this study is to describe our initial clinical experience with dual-energy computed tomography (DECT) virtual non-calcium (VNC) images for the detection of bone marrow (BM) edema in patients with suspected hip fracture following trauma. Twenty-five patients presented to the emergency department at a level 1 trauma center between January 1, 2011 and January 1, 2013 with clinical suspicion of hip fracture and normal radiographs were included. All CT scans were performed on a dual-source, dual-energy CT system. VNC images were generated using prototype software and were compared to regular bone reconstructions by two musculoskeletal radiologists in consensus. Radiological and/or clinical diagnosis of fracture at 30-day follow-up was used as the reference standard. Twenty-one patients were found to have DECT-VNC signs of bone marrow edema. Eighteen of these 21 patients were true positive and three were false positive. A concordant fracture was clearly seen on bone reconstruction images in 15 of the 18 true positive cases. In three cases, DECT-VNC was positive for bone marrow edema where bone reconstruction CT images were negative. Four patients demonstrated no DECT-VNC signs of bone marrow edema: two cases were true negative, two cases were false negative. When compared with the gold standard of hip fracture determined at retrospective follow-up, the sensitivity of DECT-VNC images of the hip was 90 %, specificity was 40 %, positive predictive value was 86 %, and negative predictive value was 50 %. Our initial experience would suggest that DECT-VNC is highly sensitive but poorly specific in the diagnosis of hip fractures in patients with normal radiographs. The value of DECT-VNC primarily lies in its ability to help detect fractures which may be subtle or undetectable on bone reconstruction CT images.
Dual Resonant Frequencies Effects on an Induction-Based Oil Palm Fruit Sensor
Harun, Noor Hasmiza; Misron, Norhisam; Sidek, Roslina Mohd; Aris, Ishak; Wakiwaka, Hiroyuki; Tashiro, Kunihisa
2014-01-01
As the main exporter in the oil palm industry, the need to improve the quality of palm oil has become the main interest among all the palm oil millers in Malaysia. To produce good quality palm oil, it is important for the miller to harvest a good oil palm Fresh Fruit Bunch (FFB). Conventionally, the main reference used by Malaysian harvesters is the manual grading standard published by the Malaysian Palm Oil Board (MPOB). A good oil palm FFB consists of all matured fruitlets, aged between 18 to 21 weeks of antheses (WAA). To expedite the harvesting process, it is crucial to implement an automated detection system for determining the maturity of the oil palm FFB. Various automated detection methods have been proposed by researchers in the field to replace the conventional method. In our preliminary study, a novel oil palm fruit sensor to detect the maturity of oil palm fruit bunch was proposed. The design of the proposed air coil sensor based on the inductive sensor was further investigated mainly in the context of the effect of coil diameter to improve its sensitivity. In this paper, the sensitivity of the inductive sensor was further examined with a dual flat-type shape of air coil. The dual air coils were tested on fifteen samples of fruitlet from two categories, namely ripe and unripe. Samples were tested within 20 Hz to 10 MHz while evaluations on both peaks were done separately before the gap between peaks was analyzed. A comparative analysis was conducted to investigate the improvement in sensitivity of the induction-based oil palm fruit sensor as compared to previous works. Results from the comparative study proved that the inductive sensor using a dual flat-type shape air coil has improved by up to 167%. This provides an indication in the improvement in the coil sensitivity of the palm oil fruit sensor based on the induction concept. PMID:25414970
TRESP II testing of AFS dual fuel system.
DOT National Transportation Integrated Search
2013-11-01
A dual fuel CNG and diesel system was retrofitted to a 13 L Volvo semi tractor for testing to verify the : fuel economy and CNG substitution rate. The semi tractor was tested on interstate and mountainous : highway routes with a loaded trailer. Fuel ...
Lesaint, Florian; Sigaud, Olivier; Khamassi, Mehdi
2014-01-01
Animals, including Humans, are prone to develop persistent maladaptive and suboptimal behaviours. Some of these behaviours have been suggested to arise from interactions between brain systems of Pavlovian conditioning, the acquisition of responses to initially neutral stimuli previously paired with rewards, and instrumental conditioning, the acquisition of active behaviours leading to rewards. However the mechanics of these systems and their interactions are still unclear. While extensively studied independently, few models have been developed to account for these interactions. On some experiment, pigeons have been observed to display a maladaptive behaviour that some suggest to involve conflicts between Pavlovian and instrumental conditioning. In a procedure referred as negative automaintenance, a key light is paired with the subsequent delivery of food, however any peck towards the key light results in the omission of the reward. Studies showed that in such procedure some pigeons persisted in pecking to a substantial level despite its negative consequence, while others learned to refrain from pecking and maximized their cumulative rewards. Furthermore, the pigeons that were unable to refrain from pecking could nevertheless shift their pecks towards a harmless alternative key light. We confronted a computational model that combines dual-learning systems and factored representations, recently developed to account for sign-tracking and goal-tracking behaviours in rats, to these negative automaintenance experimental data. We show that it can explain the variability of the observed behaviours and the capacity of alternative key lights to distract pigeons from their detrimental behaviours. These results confirm the proposed model as an interesting tool to reproduce experiments that could involve interactions between Pavlovian and instrumental conditioning. The model allows us to draw predictions that may be experimentally verified, which could help further investigate the neural mechanisms underlying theses interactions. PMID:25347531
A Three-Level Analysis of Collaborative Learning in Dual-Interaction Spaces
ERIC Educational Resources Information Center
Lonchamp, Jacques
2009-01-01
CSCL systems which follow the dual-interaction spaces paradigm support the synchronous construction and discussion of shared artifacts by distributed or colocated small groups of learners. The most recent generic dual-interaction space environments, either model based or component based, can be deeply customized by teachers for supporting…
Calibration of a dual-PTZ camera system for stereo vision
NASA Astrophysics Data System (ADS)
Chang, Yau-Zen; Hou, Jung-Fu; Tsao, Yi Hsiang; Lee, Shih-Tseng
2010-08-01
In this paper, we propose a calibration process for the intrinsic and extrinsic parameters of dual-PTZ camera systems. The calibration is based on a complete definition of six coordinate systems fixed at the image planes, and the pan and tilt rotation axes of the cameras. Misalignments between estimated and ideal coordinates of image corners are formed into cost values to be solved by the Nelder-Mead simplex optimization method. Experimental results show that the system is able to obtain 3D coordinates of objects with a consistent accuracy of 1 mm when the distance between the dual-PTZ camera set and the objects are from 0.9 to 1.1 meters.
Analyzing the biosensor signal in flows: studies with glucose optrodes.
Kivirand, K; Floren, A; Kagan, M; Avarmaa, T; Rinken, T; Jaaniso, R
2015-01-01
Responses of enzymatic bio-optrodes in flow regime were studied and an original model was proposed with the aim of establishing a reliable method for a quick determination of biosensor signal parameters, applicable for biosensor calibration. A dual-optrode glucose biosensor, comprising of a glucose bio-optrode and a reference oxygen optrode, both placed into identical flow channels, was developed and used as a model system. The signal parameters of this biosensor at different substrate concentrations were not dependent on the speed of the probe flow and could be determined from the initial part of the biosensor transient phase signal, providing a valuable tool for rapid analysis. In addition, the model helped to design the biosensor system with reduced impact of enzyme inactivation to the system stability (20% decrease of the enzyme activity lead to only a 1% decrease of the slope of the calibration curve) and hence significantly prolong the effective lifetime of bio-optrodes. Copyright © 2014 Elsevier B.V. All rights reserved.
Trace explosives sensor testbed (TESTbed)
NASA Astrophysics Data System (ADS)
Collins, Greg E.; Malito, Michael P.; Tamanaha, Cy R.; Hammond, Mark H.; Giordano, Braden C.; Lubrano, Adam L.; Field, Christopher R.; Rogers, Duane A.; Jeffries, Russell A.; Colton, Richard J.; Rose-Pehrsson, Susan L.
2017-03-01
A novel vapor delivery testbed, referred to as the Trace Explosives Sensor Testbed, or TESTbed, is demonstrated that is amenable to both high- and low-volatility explosives vapors including nitromethane, nitroglycerine, ethylene glycol dinitrate, triacetone triperoxide, 2,4,6-trinitrotoluene, pentaerythritol tetranitrate, and hexahydro-1,3,5-trinitro-1,3,5-triazine. The TESTbed incorporates a six-port dual-line manifold system allowing for rapid actuation between a dedicated clean air source and a trace explosives vapor source. Explosives and explosives-related vapors can be sourced through a number of means including gas cylinders, permeation tube ovens, dynamic headspace chambers, and a Pneumatically Modulated Liquid Delivery System coupled to a perfluoroalkoxy total-consumption microflow nebulizer. Key features of the TESTbed include continuous and pulseless control of trace vapor concentrations with wide dynamic range of concentration generation, six sampling ports with reproducible vapor profile outputs, limited low-volatility explosives adsorption to the manifold surface, temperature and humidity control of the vapor stream, and a graphical user interface for system operation and testing protocol implementation.
Design of a Nested Eight-Channel Sodium and Four-Channel Proton Coil for 7 Tesla Knee Imaging
Brown, Ryan; Madelin, Guillaume; Lattanzi, Riccardo; Chang, Gregory; Regatte, Ravinder R.; Sodickson, Daniel K.; Wiggins, Graham C.
2012-01-01
The critical design aim for a dual-tuned sodium/proton coil is to maximize sodium sensitivity and transmit field (B1+) homogeneity while simultaneously providing adequate proton sensitivity and homogeneity. While most dual-frequency coils utilize lossy high-impedance trap circuits or PIN diodes to allow dual-resonance, we explored a nested-coil design for sodium/proton knee imaging at 7T. A stand-alone eight-channel sodium receive array was implemented without standard dual-resonance circuitry to provide improved sodium signal-to-noise ratio (SNR) over a volume coil. A detunable sodium birdcage was added for homogeneous sodium excitation and a four-channel proton transmit-receive array was added to provide anatomical reference imaging and B0 shimming capability. Both modules were implemented with minimal disturbance to the eight-channel sodium array by managing their respective resonances and geometrical arrangement. In vivo sodium SNR was 1.2 to 1.7 times greater in the developed eight-channel array than in a mono-nuclear sodium birdcage coil, while the developed four-channel proton array provided SNR similar to that of a commercial mono-nuclear proton birdcage coil. PMID:22887123
On-chip dual-comb source for spectroscopy
Dutt, Avik; Joshi, Chaitanya; Ji, Xingchen; Cardenas, Jaime; Okawachi, Yoshitomo; Luke, Kevin; Gaeta, Alexander L.; Lipson, Michal
2018-01-01
Dual-comb spectroscopy is a powerful technique for real-time, broadband optical sampling of molecular spectra, which requires no moving components. Recent developments with microresonator-based platforms have enabled frequency combs at the chip scale. However, the need to precisely match the resonance wavelengths of distinct high quality-factor microcavities has hindered the development of on-chip dual combs. We report the simultaneous generation of two microresonator combs on the same chip from a single laser, drastically reducing experimental complexity. We demonstrate broadband optical spectra spanning 51 THz and low-noise operation of both combs by deterministically tuning into soliton mode-locked states using integrated microheaters, resulting in narrow (<10 kHz) microwave beat notes. We further use one comb as a reference to probe the formation dynamics of the other comb, thus introducing a technique to investigate comb evolution without auxiliary lasers or microwave oscillators. We demonstrate high signal-to-noise ratio absorption spectroscopy spanning 170 nm using the dual-comb source over a 20-μs acquisition time. Our device paves the way for compact and robust spectrometers at nanosecond time scales enabled by large beat-note spacings (>1 GHz). PMID:29511733
Temperature dependence of corrosion of ferritic stainless steel in dual atmosphere at 600-800 °C
NASA Astrophysics Data System (ADS)
Alnegren, Patrik; Sattari, Mohammad; Svensson, Jan-Erik; Froitzheim, Jan
2018-07-01
The ferritic stainless steel AISI 441 (EN 1.4509) is exposed for 1000 h to air - 3% H2O on one side and to Ar - 5% H2 - 3% H2O on the other at temperatures 600, 700, and 800 °C. Conditions are chosen to mimic the environment of metallic interconnects in an operating solid oxide fuel cell (SOFC). At 600 °C, ∼25 μm thick Fe2O3/(Fe,Cr)3O4 forms on large parts of the air side of the samples. Reference samples exposed to air - 3% H2O on both sides form thin protective layers of (Cr,Mn)3O4/Cr2O3 at the same temperature. At higher temperatures, 700 and 800 °C, all samples form protective layers of (Cr,Mn)3O4/Cr2O3 regardless of exposure to single or dual atmosphere. It is concluded that corrosion resistance in a dual atmosphere has an inverse dependence on temperature. Different hypotheses for the underlying cause for the dual atmosphere effect are discussed and compared to the experimental data.
Virtual identification of novel PPARα/γ dual agonists by scaffold hopping of saroglitazar.
Jia, Wen-Qing; Jing, Zhi; Liu, Xin; Feng, Xiao-Yan; Liu, Ya-Ya; Wang, Shu-Qing; Xu, Wei-Ren; Liu, Jian-Wen; Cheng, Xian-Chao
2017-10-28
The thiazolidinedione class PPARγ agonists as antidiabetic agents are restricted in clinical use because of the side effects such as edema, weight gain, and heart failure. The single and selective agonism of PPARγ is the main cause of side effects. The multi-target cooperative PPARα/γ dual agonist development is a hot topic in the antidiabetic medicinal chemistry field. Saroglitazar is the first approved PPARα/γ dual agonist, available in India for the treatment of diabetic dyslipidemia. It got rid of these side effects. With the aim of finding more protent PPARα/γ dual agonists, the scaffold hopping was used to replace α-o phenylpropionic acid skeleton of saroglitazar with L-tyrosine skeleton. Then, the structural modification was carried out designing 72 compounds. Considering the importance of chirality, opposite configuration of 72 compounds was also studied. 12 compounds with better -cdocker energy were screened by molecular docking. Subsequently, the pharmacokinetic properties and toxicity evaluated by ADMET prediction, 11 of them showed better properties. Comp#L-17-1 and comp#L-3-1 were regarded as representatives to study the binding stability by molecular dynamics (MD) simulations. The MD simulation results of comp#L-17-1-PPARs (α, γ) and comp#L-3-1-PPARs (α, γ) provided structure reference for the research and development of novel PPARα/γ dual agonists.
The Calibration of AVHRR Visible Dual Gain using Meteosat-8 for NOAA-16 to 18
NASA Technical Reports Server (NTRS)
Doelling, David R.; Garber, Donald P.; Avey, L. A.; Nguyen, Louis; Minnis, Patrick
2007-01-01
The NOAA AVHRR program has given the remote sensing community over 25 years of imager radiances to retrieve global cloud, vegetation, and aerosol properties. This dataset can be used for long-term climate research, if the AVHRR instrument is well calibrated. Unfortunately, the AVHRR instrument does not have onboard visible calibration and does degrade over time. Vicarious post-launch calibration is necessary to obtain cloud properties that are not biased over time. The recent AVHRR-3 instrument has a dual gain in the visible channels in order to achieve greater radiance resolution in the clear-sky. This has made vicarious calibration of the AVHRR-3 more difficult to unravel. Reference satellite radiances from well-calibrated instruments, usually equipped with solar diffusers, such as MODIS, have been used to successfully vicariously calibrate other visible instruments. Transfer of calibration from one satellite to another using co-angled, collocated, coincident radiances has been well validated. Terra or Aqua MODIS and AVHRR comparisons can only be performed over the poles during summer. However, geostationary satellites offer a transfer medium that captures both parts of the dual gain. This AVHRR-3 calibration strategy uses, calibrated with MODIS, Meteosat-8 radiances simultaneously to determine the dual gains using 50km regions. The dual gain coefficients will be compared with the nominal coefficients. Results will be shown for all visible channels for NOAA-17.
2014-01-01
Background Many full-time Ugandan government health providers take on additional jobs – a phenomenon called dual practice. We describe the complex patterns that characterize the evolution of dual practice in Uganda, and the local management practices that emerged in response, in five government facilities. An in-depth understanding of dual practice can contribute to policy discussions on improving public sector performance. Methods A multiple case study design with embedded units of analysis was supplemented by interviews with policy stakeholders and a review of historical and policy documents. Five facility case studies captured the perspective of doctors, nurses, and health managers through semi-structured in-depth interviews. A causal loop diagram illustrated interactions and feedback between old and new actors, as well as emerging roles and relationships. Results The causal loop diagram illustrated how feedback related to dual practice policy developed in Uganda. As opportunities for dual practice grew and the public health system declined over time, government providers increasingly coped through dual practice. Over time, government restrictions to dual practice triggered policy resistance and protest from government providers. Resulting feedback contributed to compromising the supply of government providers and, potentially, of service delivery outcomes. Informal government policies and restrictions replaced the formal restrictions identified in the early phases. In some instances, government health managers, particularly those in hospitals, developed their own practices to cope with dual practice and to maintain public sector performance. Management practices varied according to the health manager’s attitude towards dual practice and personal experience with dual practice. These practices were distinct in hospitals. Hospitals faced challenges managing internal dual practice opportunities, such as those created by externally-funded research projects based within the hospital. Private wings’ inefficiencies and strict fee schedule made them undesirable work locations for providers. Conclusions Dual practice prevails because public and private sector incentives, non-financial and financial, are complementary. Local management practices for dual practice have not been previously documented and provide learning opportunities to inform policy discussions. Understanding how dual practice evolves and how it is managed locally is essential for health workforce policy, planning, and performance discussions in Uganda and similar settings. PMID:25134522
ERIC Educational Resources Information Center
Jacobs, Jonathan; North, Tom
2008-01-01
A dual credit course is a college/university level course that is taught at a high school, by a high school teacher, in partnership with a community college (CCWD) or Oregon University System (OUS) institution. Successful completion of a dual credit course counts as credit for both high school and college. In 2005-06, about 12,000 students took…
Using dual-purpose crops in sheep-grazing systems.
Dove, Hugh; Kirkegaard, John
2014-05-01
The utilisation of dual-purpose crops, especially wheat and canola grown for forage and grain production in sheep-grazing systems, is reviewed. When sown early and grazed in winter before stem elongation, later-maturing wheat and canola crops can be grazed with little impact on grain yield. Recent research has sought to develop crop- and grazing-management strategies for dual-purpose crops. Aspects examined have been grazing effects on crop growth, recovery and yield development along with an understanding of the grazing value of the crop fodder, its implications for animal nutrition and grazing management to maximise live-weight gain. By alleviating the winter 'feed gap', the increase in winter stocking rate afforded by grazing crops allows crop and livestock production to be increased simultaneously on the same farm. Integration of dual-purpose wheat with canola on mixed farms provides further systems advantages related to widened operational windows, weed and disease control and risk management. Dual-purpose crops are an innovation that has potential to assist in addressing the global food-security challenge. © 2013 Society of Chemical Industry.
Technology requirements for advanced earth-orbital transportation systems, dual-mode propulsion
NASA Technical Reports Server (NTRS)
Haefeli, R. C.; Littler, E. G.; Hurley, J. B.; Winter, M. G.
1977-01-01
The application of dual-mode propulsion concepts to fully reusable single-stage-to-orbit (SSTO) vehicles is discussed. Dual-mode propulsion uses main rocket engines that consume hydrocarbon fuels as well as liquid hydrogen fuel. Liquid oxygen is used as the oxidizer. These engine concepts were integrated into transportation vehicle designs capable of vertical takeoff, delivering a payload to earth orbit, and return to earth with a horizontal landing. Benefits of these vehicles were assessed and compared with vehicles using single-mode propulsion (liquid hydrogen and oxygen engines). Technology requirements for such advanced transportation systems were identified. Figures of merit, including life-cycle cost savings and research costs, were derived for dual-mode technology programs, and were used for assessments of potential benefits of proposed technology activities. Dual-mode propulsion concepts display potential for significant cost and performance benefits when applied to SSTO vehicles.
Xu, Tong; Ducote, Justin L.; Wong, Jerry T.; Molloi, Sabee
2011-01-01
Dual-energy chest radiography has the potential to provide better diagnosis of lung disease by removing the bone signal from the image. Dynamic dual-energy radiography is now possible with the introduction of digital flat panel detectors. The purpose of this study is to evaluate the feasibility of using dynamic dual-energy chest radiography for functional lung imaging and tumor motion assessment. The dual energy system used in this study can acquire up to 15 frame of dual-energy images per second. A swine animal model was mechanically ventilated and imaged using the dual-energy system. Sequences of soft-tissue images were obtained using dual-energy subtraction. Time subtracted soft-tissue images were shown to be able to provide information on regional ventilation. Motion tracking of a lung anatomic feature (a branch of pulmonary artery) was performed based on an image cross-correlation algorithm. The tracking precision was found to be better than 1 mm. An adaptive correlation model was established between the above tracked motion and an external surrogate signal (temperature within the tracheal tube). This model is used to predict lung feature motion using the continuous surrogate signal and low frame rate dual-energy images (0.1 to 3.0 frames /sec). The average RMS error of the prediction was (1.1 ± 0.3) mm. The dynamic dual-energy was shown to be potentially useful for lung functional imaging such as regional ventilation and kinetic studies. It can also be used for lung tumor motion assessment and prediction during radiation therapy. PMID:21285477
Xu, Tong; Ducote, Justin L; Wong, Jerry T; Molloi, Sabee
2011-02-21
Dual-energy chest radiography has the potential to provide better diagnosis of lung disease by removing the bone signal from the image. Dynamic dual-energy radiography is now possible with the introduction of digital flat-panel detectors. The purpose of this study is to evaluate the feasibility of using dynamic dual-energy chest radiography for functional lung imaging and tumor motion assessment. The dual-energy system used in this study can acquire up to 15 frames of dual-energy images per second. A swine animal model was mechanically ventilated and imaged using the dual-energy system. Sequences of soft-tissue images were obtained using dual-energy subtraction. Time subtracted soft-tissue images were shown to be able to provide information on regional ventilation. Motion tracking of a lung anatomic feature (a branch of pulmonary artery) was performed based on an image cross-correlation algorithm. The tracking precision was found to be better than 1 mm. An adaptive correlation model was established between the above tracked motion and an external surrogate signal (temperature within the tracheal tube). This model is used to predict lung feature motion using the continuous surrogate signal and low frame rate dual-energy images (0.1-3.0 frames per second). The average RMS error of the prediction was (1.1 ± 0.3) mm. The dynamic dual energy was shown to be potentially useful for lung functional imaging such as regional ventilation and kinetic studies. It can also be used for lung tumor motion assessment and prediction during radiation therapy.
Isotopic signals of denitrification in a northern hardwood forested catchment
NASA Astrophysics Data System (ADS)
Wexler, Sarah; Goodale, Christine
2013-04-01
Water samples from streams, groundwater and precipitation were collected during summer from the hydrologic reference watershed (W3) at Hubbard Brook Experimental Forest in the White Mountains, New Hampshire, and analysed for d15N-NO3 and d18O-NO3. Despite very low nitrate concentrations (<0.5 to 8.8 uM NO3-) dual-isotopic signals of sources and processes were clearly distinguishable. The isotopic composition of nitrate from shallow groundwater showed evidence of dual isotopic fractionation in line with denitrification, with a positive relationship between nitrogen and oxygen isotopic composition, a regression line slope of 0.76 (r2 = 0.68), and an empirical isotope enrichment factor of ɛP-S 15N-NO3 -12.7%. The isotopic composition of riparian groundwater nitrate from time-series samples showed variation in processes over a small spatial scale. The expected isotopic composition of nitrate sources in the watershed was used to distinguish nitrate in rain and nitrate from nitrification of both rainfall ammonium and ammonium from mineralised soil organic nitrogen. Evidence of oxygen exchange with water during nitrification was seen in the isotopic composition of stream and shallow groundwater nitrate. The isotopic composition of streamwater nitrate following a period of storms indicated that 25% of nitrate in the streamwater was of atmospheric origin. This suggests rapid infiltration of rainfall via vertical bypass flow to the saturated zone, enabling transport of atmospheric nitrate to the stream channels. Across the Hubbard Brook basin, the isotopic composition of nitrate from paired samples from watersheds 4-7 indicated a switch between a nitrification and assimilation dominated system, to a system influenced by rainfall nitrogen inputs and denitrification. The dual isotope approach has revealed evidence of denitrification of nitrate from different sources at low concentrations at Hubbard Brook during summer. This isotopic evidence deepens our understanding of the significance and spatial variability of denitrification in environments with low levels of nitrate, represented by this northern hardwood forested catchment.
NASA Astrophysics Data System (ADS)
Yousefian Jazi, Nima
Spatial filtering and directional discrimination has been shown to be an effective pre-processing approach for noise reduction in microphone array systems. In dual-microphone hearing aids, fixed and adaptive beamforming techniques are the most common solutions for enhancing the desired speech and rejecting unwanted signals captured by the microphones. In fact, beamformers are widely utilized in systems where spatial properties of target source (usually in front of the listener) is assumed to be known. In this dissertation, some dual-microphone coherence-based speech enhancement techniques applicable to hearing aids are proposed. All proposed algorithms operate in the frequency domain and (like traditional beamforming techniques) are purely based on the spatial properties of the desired speech source and does not require any knowledge of noise statistics for calculating the noise reduction filter. This benefit gives our algorithms the ability to address adverse noise conditions, such as situations where interfering talker(s) speaks simultaneously with the target speaker. In such cases, the (adaptive) beamformers lose their effectiveness in suppressing interference, since the noise channel (reference) cannot be built and updated accordingly. This difference is the main advantage of the proposed techniques in the dissertation over traditional adaptive beamformers. Furthermore, since the suggested algorithms are independent of noise estimation, they offer significant improvement in scenarios that the power level of interfering sources are much more than that of target speech. The dissertation also shows the premise behind the proposed algorithms can be extended and employed to binaural hearing aids. The main purpose of the investigated techniques is to enhance the intelligibility level of speech, measured through subjective listening tests with normal hearing and cochlear implant listeners. However, the improvement in quality of the output speech achieved by the algorithms are also presented to show that the proposed methods can be potential candidates for future use in commercial hearing aids and cochlear implant devices.
Dual fuel injection piggyback controller system
NASA Astrophysics Data System (ADS)
Muji, Siti Zarina Mohd.; Hassanal, Muhammad Amirul Hafeez; Lee, Chua King; Fawzi, Mas; Zulkifli, Fathul Hakim
2017-09-01
Dual-fuel injection is an effort to reduce the dependency on diesel and gasoline fuel. Generally, there are two approaches to implement the dual-fuel injection in car system. The first approach is changing the whole injector of the car engine, the consequence is excessive high cost. Alternatively, it also can be achieved by manipulating the system's control signal especially the Electronic Control Unit (ECU) signal. Hence, the study focuses to develop a dual injection timing controller system that likely adopted to control injection time and quantity of compressed natural gas (CNG) and diesel fuel. In this system, Raspberry Pi 3 reacts as main controller unit to receive ECU signal, analyze it and then manipulate its duty cycle to be fed into the Electronic Driver Unit (EDU). The manipulation has changed the duty cycle to two pulses instead of single pulse. A particular pulse mainly used to control injection of diesel fuel and another pulse controls injection of Compressed Natural Gas (CNG). The test indicated promising results that the system can be implemented in the car as piggyback system. This article, which was originally published online on 14 September 2017, contained an error in the acknowledgment section. The corrected acknowledgment appears in the Corrigendum attached to the pdf.
Implementation and applications of dual-modality imaging
NASA Astrophysics Data System (ADS)
Hasegawa, Bruce H.; Barber, William C.; Funk, Tobias; Hwang, Andrew B.; Taylor, Carmen; Sun, Mingshan; Seo, Youngho
2004-06-01
In medical diagnosis, functional or physiological data can be acquired using radionuclide imaging with positron emission tomography or with single-photon emission computed tomography. However, anatomical or structural data can be acquired using X-ray computed tomography. In dual-modality imaging, both radionuclide and X-ray detectors are incorporated in an imaging system to allow both functional and structural data to be acquired in a single procedure without removing the patient from the imaging system. In a clinical setting, dual-modality imaging systems commonly are used to localize radiopharmaceutical uptake with respect to the patient's anatomy. This helps the clinician to differentiate disease from regions of normal radiopharmaceutical accumulation, to improve diagnosis or cancer staging, or to facilitate planning for radiation therapy or surgery. While initial applications of dual-modality imaging were developed for clinical imaging on humans, it now is recognized that these systems have potentially important applications for imaging small animals involved in experimental studies including basic investigations of mammalian biology and development of new pharmaceuticals for diagnosis or treatment of disease.
Dual-energy micro-CT with a dual-layer, dual-color, single-crystal scintillator.
Maier, Daniel Simon; Schock, Jonathan; Pfeiffer, Franz
2017-03-20
A wide range of X-ray imaging applications demand micrometer spatial resolution. In material science and biology especially, there is a great interest in material determination and material separation methods. Here we present a new detector design that allows the recording of a low- and a high-energy radiography image simultaneously with micrometer spatial resolution. The detector system is composed of a layered scintillator stack, two CCDs and an optical system to image the scintillator responses onto the CCDs. We used the detector system with a standard laboratory microfocus X-ray tube to prove the working principle of the system and derive important design characteristics. With the recorded and registered dual-energy data set, the material separation and determination could be shown at an X-ray tube peak energy of up to 160 keV with a spatial resolution of 12 μm. The detector design shows a great potential for further development and a wide range of possible applications.
Two-stage earth-to-orbit vehicles with dual-fuel propulsion in the Orbiter
NASA Technical Reports Server (NTRS)
Martin, J. A.
1982-01-01
Earth-to-orbit vehicle studies of future replacements for the Space Shuttle are needed to guide technology development. Previous studies that have examined single-stage vehicles have shown advantages for dual-fuel propulsion. Previous two-stage system studies have assumed all-hydrogen fuel for the Orbiters. The present study examined dual-fuel Orbiters and found that the system dry mass could be reduced with this concept. The possibility of staging the booster at a staging velocity low enough to allow coast-back to the launch site is shown to be beneficial, particularly in combination with a dual-fuel Orbiter. An engine evaluation indicated the same ranking of engines as did a previous single-stage study. Propane and RP-1 fuels result in lower vehicle dry mass than methane, and staged-combustion engines are preferred over gas-generator engines. The sensitivity to the engine selection is less for two-stage systems than for single-stage systems.
[Production of sugar syrup containing rare sugar using dual-enzyme coupled reaction system].
Han, Wenjia; Zhu, Yueming; Bai, Wei; Izumori, Ken; Zhang, Tongcun; Sun, Yuanxia
2014-01-01
Enzymatic conversion is very important to produce functional rare sugars, but the conversion rate of single enzymes is generally low. To increase the conversion rate, a dual-enzyme coupled reaction system was developed. Dual-enzyme coupled reaction system was constructed using D-psicose-3-epimerase (DPE) and L-rhamnose isomerase (L-RhI), and used to convert D-fructose to D-psicose and D-allose. The ratio of DPE and L-RhI was 1:10 (W/W), and the concentration of DPE was 0.05 mg/mL. The optimum temperature was 60 degrees C and pH was 9.0. When the concentration of D-fructose was 2%, the reaction reached its equilibrium after 10 h, and the yield of D-psicose and D-allose was 5.12 and 2.04 g/L, respectively. Using the dual-enzymes coupled system developed in the current study, we could obtain sugar syrup containing functional rare sugar from fructose-rich raw material, such as high fructose corn syrup.
ERIC Educational Resources Information Center
Zholdasbekova, Saule; Nurzhanbayeva, Zhanet; Mavedov, Rixsibai; Saipov, Amangeldi; Zhiyentayeva, Begaim; Tlemissova, Alja
2016-01-01
The purpose of the article consists in representation to discussion by specialists of the revealed didactic conditions of enhancement of preparation of the pedagogical personnel in higher education institution to dual training in the system of vocational and educational training. Modeling, aspect system, comparative and structural analyses…
ERIC Educational Resources Information Center
Sager, Fritz
2008-01-01
The dual system of vocational training, utilising both company training and vocational school attendance, is generally acknowledged to be a successful model for reducing youth unemployment. However, the decreasing number of training opportunities in countries with this system poses a crisis for the approach. One strategy for overcoming the problem…
Efficient sidelobe ASK based dual-function radar-communications
NASA Astrophysics Data System (ADS)
Hassanien, Aboulnasr; Amin, Moeness G.; Zhang, Yimin D.; Ahmad, Fauzia
2016-05-01
Recently, dual-function radar-communications (DFRC) has been proposed as means to mitigate the spectrum congestion problem. Existing amplitude-shift keying (ASK) methods for information embedding do not take full advantage of the highest permissable sidelobe level. In this paper, a new ASK-based signaling strategy for enhancing the signal-to-noise ratio (SNR) at the communication receiver is proposed. The proposed method employs one reference waveform and simultaneously transmits a number of orthogonal waveforms equals to the number of 1's in the binary sequence being embedded. 3 dB SNR gain is achieved using the proposed method as compared to existing sidelobe ASK methods. The effectiveness of the proposed information embedding strategy is verified using simulations examples.
Poder, Thomas G; Godbout, Sylvie T; Bellemare, Christian
This paper describes a comparative study of clinical coding by Archivists (also known as Clinical Coders in some other countries) using single and dual computer monitors. In the present context, processing a record corresponds to checking the available information; searching for the missing physician information; and finally, performing clinical coding. We collected data for each Archivist during her use of the single monitor for 40 hours and during her use of the dual monitor for 20 hours. During the experimental periods, Archivists did not perform other related duties, so we were able to measure the real-time processing of records. To control for the type of records and their impact on the process time required, we categorised the cases as major or minor, based on whether acute care or day surgery was involved. Overall results show that 1,234 records were processed using a single monitor and 647 records using a dual monitor. The time required to process a record was significantly higher (p= .071) with a single monitor compared to a dual monitor (19.83 vs.18.73 minutes). However, the percentage of major cases was significantly higher (p= .000) in the single monitor group compared to the dual monitor group (78% vs. 69%). As a consequence, we adjusted our results, which reduced the difference in time required to process a record between the two systems from 1.1 to 0.61 minutes. Thus, the net real-time difference was only 37 seconds in favour of the dual monitor system. Extrapolated over a 5-year period, this would represent a time savings of 3.1% and generate a net cost savings of $7,729 CAD (Canadian dollars) for each workstation that devoted 35 hours per week to the processing of records. Finally, satisfaction questionnaire responses indicated a high level of satisfaction and support for the dual-monitor system. The implementation of a dual-monitor system in a hospital archiving department is an efficient option in the context of scarce human resources and has the strong support of Archivists.
Playgroups as Protective Environments for Refugee Children at Risk of Trauma
ERIC Educational Resources Information Center
Jackson, Dianne
2006-01-01
Refugee families in Australia generally have a dual challenge--dealing with past traumatic experiences while facing the struggles of integrating with a new and unfamiliar society. For children and their families who have experienced war-related trauma and disruption, the resettlement process is being referred to as "secondary trauma" to…
Postsecondary Enrollment Options (PSEO) Reference Guide
ERIC Educational Resources Information Center
Minnesota Department of Education, 2017
2017-01-01
The PSEO program is a dual credit program that allows high school students to simultaneously earn high school and college credit through enrollment in and successful completion of college-level courses on a college campus or online. Students may take PSEO courses on a full- or part-time basis. The PSEO program provides students with a greater…
30 CFR 206.176 - How do I perform accounting for comparison?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I perform accounting for comparison? 206... REVENUE MANAGEMENT PRODUCT VALUATION Indian Gas § 206.176 How do I perform accounting for comparison? (a... requires accounting for comparison (also referred to as actual dual accounting). Except as provided in...
USDA-ARS?s Scientific Manuscript database
Current approaches to scheduling crop irrigation using reference evapotranspiration (ET0) recommend using a dual-coefficient approach using basal (Kcb) and soil (Ke) coefficients along with a stress coefficient (Ks) to model crop evapotranspiration (ETc), [e.g. ETc=(Ks*Kcb+Ke)*ET0]. However, indepe...
ERIC Educational Resources Information Center
Ziegler, Nicholas Allan
2014-01-01
The European Language Portfolio (ELP) is an alternative assessment used in foreign language classes throughout Europe to support and record language learning. Directly linked to the Common European Framework of Reference for Languages (Council of Europe, 2001) proficiency guidelines, it is designed to achieve an ambitious dual goal: document…
ERIC Educational Resources Information Center
Biegel, David E.; Stevenson, Lauren D.; Beimers, David; Ronis, Robert J.; Boyle, Patrick
2010-01-01
Objectives: This study examines consumer and agency level predictors of competitive employment for consumers with co-occurring disorders. Methods: The study sample included 191 consumers from mental health agencies receiving Integrated Dual Diagnosis Treatment services, including a subgroup which was referred for Supported Employment Services.…
Haidar, Ahmad; Messier, Virginie; Legault, Laurent; Ladouceur, Martin; Rabasa-Lhoret, Rémi
2017-05-01
To assess whether the dual-hormone (insulin and glucagon) artificial pancreas reduces hypoglycaemia compared to the single-hormone (insulin alone) artificial pancreas in outpatient settings during the day and night. In a randomized, three-way, crossover trial we compared the dual-hormone artificial pancreas, the single-hormone artificial pancreas and sensor-augmented pump therapy (control) in 23 adults with type 1 diabetes. Each intervention was applied from 8 AM Day 1 to 8 PM Day 3 (60 hours) in outpatient free-living conditions. The primary outcome was time spent with sensor glucose levels below 4.0 mmol/L. A P value of less than .017 was regarded as significant. The median difference between the dual-hormone system and the single-hormone system was -2.3% (P = .072) for time spent below 4.0 mmol/L, -1.3% (P = .017) for time below 3.5 mmol/L, and -0.7% (P = .031) for time below 3.3 mmol/L. Both systems reduced (P < .017) hypoglycaemia below 4.0, 3.5 and 3.3 mmol/L compared to control therapy, but reductions were larger with the dual-hormone system than with the single-hormone system (medians -4.0% vs -3.4% for 4.0 mmol/L; -2.7% vs -2.2% for 3.5 mmol/L; and -2.2% vs -1.2% for 3.3 mmol/L). There were 34 hypoglycaemic events (<3.0 mmol/L for 20 minutes) with control therapy, 14 with the single-hormone system and 6 with the dual-hormone system. These differences in hypoglycaemia were observed while mean glucose level was low and comparable in all interventions (P = NS). The dual-hormone artificial pancreas had the lowest risk of hypoglycaemia, but the differences were not statistically significant. Larger studies are needed. © 2017 John Wiley & Sons Ltd.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Khare, Surhud; Somasekhar, Dinesh; More, Ankit
Described is an apparatus which comprises: a Network-On-Chip fabric using crossbar switches, having distributed ingress and egress ports; and a dual-mode network interface coupled to at least one crossbar switch, the dual-mode network interface is to include: a dual-mode circuitry; a controller operable to: configure the dual-mode circuitry to transmit and receive differential signals via the egress and ingress ports, respectively, and configure the dual-mode circuitry to transmit and receive signal-ended signals via the egress and ingress ports, respectively.
Chiang, Mao-Hsiung
2010-01-01
This study aims to develop a X-Y dual-axial intelligent servo pneumatic-piezoelectric hybrid actuator for position control with high response, large stroke (250 mm, 200 mm) and nanometer accuracy (20 nm). In each axis, the rodless pneumatic actuator serves to position in coarse stroke and the piezoelectric actuator compensates in fine stroke. Thus, the overall control systems of the single axis become a dual-input single-output (DISO) system. Although the rodless pneumatic actuator has relatively larger friction force, it has the advantage of mechanism for multi-axial development. Thus, the X-Y dual-axial positioning system is developed based on the servo pneumatic-piezoelectric hybrid actuator. In addition, the decoupling self-organizing fuzzy sliding mode control is developed as the intelligent control strategies. Finally, the proposed novel intelligent X-Y dual-axial servo pneumatic-piezoelectric hybrid actuators are implemented and verified experimentally.
Adapting Nielsen’s Design Heuristics to Dual Processing for Clinical Decision Support
Taft, Teresa; Staes, Catherine; Slager, Stacey; Weir, Charlene
2016-01-01
The study objective was to improve the applicability of Nielson’s standard design heuristics for evaluating electronic health record (EHR) alerts and linked ordering support by integrating them with Dual Process theory. Through initial heuristic evaluation and a user study of 7 physicians, usability problems were identified. Through independent mapping of specific usability criteria to support for each of the Dual Cognitive processes (S1 and S2) and deliberation, agreement was reached on mapping criteria. Finally, usability errors from the heuristic and user study were mapped to S1 and S2. Adding a dual process perspective to specific heuristic analysis increases the applicability and relevance of computerized health information design evaluations. This mapping enables designers to measure that their systems are tailored to support attention allocation. System 1 will be supported by improving pattern recognition and saliency, and system 2 through efficiency and control of information access. PMID:28269915
Chiang, Mao-Hsiung
2010-01-01
This study aims to develop a X-Y dual-axial intelligent servo pneumatic-piezoelectric hybrid actuator for position control with high response, large stroke (250 mm, 200 mm) and nanometer accuracy (20 nm). In each axis, the rodless pneumatic actuator serves to position in coarse stroke and the piezoelectric actuator compensates in fine stroke. Thus, the overall control systems of the single axis become a dual-input single-output (DISO) system. Although the rodless pneumatic actuator has relatively larger friction force, it has the advantage of mechanism for multi-axial development. Thus, the X-Y dual-axial positioning system is developed based on the servo pneumatic-piezoelectric hybrid actuator. In addition, the decoupling self-organizing fuzzy sliding mode control is developed as the intelligent control strategies. Finally, the proposed novel intelligent X-Y dual-axial servo pneumatic-piezoelectric hybrid actuators are implemented and verified experimentally. PMID:22319266
Adapting Nielsen's Design Heuristics to Dual Processing for Clinical Decision Support.
Taft, Teresa; Staes, Catherine; Slager, Stacey; Weir, Charlene
2016-01-01
The study objective was to improve the applicability of Nielson's standard design heuristics for evaluating electronic health record (EHR) alerts and linked ordering support by integrating them with Dual Process theory. Through initial heuristic evaluation and a user study of 7 physicians, usability problems were identified. Through independent mapping of specific usability criteria to support for each of the Dual Cognitive processes (S1 and S2) and deliberation, agreement was reached on mapping criteria. Finally, usability errors from the heuristic and user study were mapped to S1 and S2. Adding a dual process perspective to specific heuristic analysis increases the applicability and relevance of computerized health information design evaluations. This mapping enables designers to measure that their systems are tailored to support attention allocation. System 1 will be supported by improving pattern recognition and saliency, and system 2 through efficiency and control of information access.
Dual-processing accounts of reasoning, judgment, and social cognition.
Evans, Jonathan St B T
2008-01-01
This article reviews a diverse set of proposals for dual processing in higher cognition within largely disconnected literatures in cognitive and social psychology. All these theories have in common the distinction between cognitive processes that are fast, automatic, and unconscious and those that are slow, deliberative, and conscious. A number of authors have recently suggested that there may be two architecturally (and evolutionarily) distinct cognitive systems underlying these dual-process accounts. However, it emerges that (a) there are multiple kinds of implicit processes described by different theorists and (b) not all of the proposed attributes of the two kinds of processing can be sensibly mapped on to two systems as currently conceived. It is suggested that while some dual-process theories are concerned with parallel competing processes involving explicit and implicit knowledge systems, others are concerned with the influence of preconscious processes that contextualize and shape deliberative reasoning and decision-making.
Mini-cavity plasma core reactors for dual-mode space nuclear power/propulsion systems. M.S. Thesis
NASA Technical Reports Server (NTRS)
Chow, S.
1976-01-01
A mini-cavity plasma core reactor is investigated for potential use in a dual-mode space power and propulsion system. In the propulsive mode, hydrogen propellant is injected radially inward through the reactor solid regions and into the cavity. The propellant is heated by both solid driver fuel elements surrounding the cavity and uranium plasma before it is exhausted out the nozzle. The propellant only removes a fraction of the driver power, the remainder is transferred by a coolant fluid to a power conversion system, which incorporates a radiator for heat rejection. Neutronic feasibility of dual mode operation and smaller reactor sizes than those previously investigated are shown to be possible. A heat transfer analysis of one such reactor shows that the dual-mode concept is applicable when power generation mode thermal power levels are within the same order of magnitude as direct thrust mode thermal power levels.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Medros, F.G.; Eldridge, J.W.; Kittrell, J.R.
1989-08-01
The objective of the research discussed in this paper was to determine if a dual-catalyst system for NO reduction with NH/sub 3/ can achieve a given percent NO reduction over a wider range of temperatures and space velocities than either catalyst used alone in the same total reactor volume. Hydrogen mordenite (20/32 mesh) and copper-ion-exchanged hydrogen mordenite (2.2% Cu) were used in series at temperatures from 200 to 600 {sup 0}C and space velocities from 1000000 to 450000 h/sup -1/ (STP). The superiority of the dual-catalyst system was demonstrated experimentally, and a model was developed which predicted its performance verymore » well from data on the individual catalysts. A technique was then developed for predicting quantitatively the dual-catalyst enhancement of the space velocity versus temperature window for achieving a given percent NO conversion.« less
Soliton microcomb range measurement.
Suh, Myoung-Gyun; Vahala, Kerry J
2018-02-23
Laser-based range measurement systems are important in many application areas, including autonomous vehicles, robotics, manufacturing, formation flying of satellites, and basic science. Coherent laser ranging systems using dual-frequency combs provide an unprecedented combination of long range, high precision, and fast update rate. We report dual-comb distance measurement using chip-based soliton microcombs. A single pump laser was used to generate dual-frequency combs within a single microresonator as counterpropagating solitons. We demonstrated time-of-flight measurement with 200-nanometer precision at an averaging time of 500 milliseconds within a range ambiguity of 16 millimeters. Measurements at distances up to 25 meters with much lower precision were also performed. Our chip-based source is an important step toward miniature dual-comb laser ranging systems that are suitable for photonic integration. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
[Treatment program for dual-diagnosis substance abusers].
Kandel, Isack
2007-01-01
Dual-diagnosis mentally ill patients, i.e. those characterized with substance abuse problems combined with mental health problems, are a challenge both for systems treating substance abusers and for mental health services. These patients are not easily integrated in either of these healthcare systems and/or are treated only for one aspect of their problem by each of these systems. For such patients it is necessary to create a separate treatment model, combining care of the problem of substance abuse and attention to the patient's mental pathology, according to his individual personality traits. For purposes of this programme a treatment setting operating on the model of a therapeutic community is proposed. This setting will open an affiliated treatment programme for dual-diagnosed patients in a separate treatment programme that is not part of the therapeutic community but will be affiliated with it and will accept dual-diagnosis patients.
Dual-Doppler Feasibility Study
NASA Technical Reports Server (NTRS)
Huddleston, Lisa L.
2012-01-01
When two or more Doppler weather radar systems are monitoring the same region, the Doppler velocities can be combined to form a three-dimensional (3-D) wind vector field thus providing for a more intuitive analysis of the wind field. A real-time display of the 3-D winds can assist forecasters in predicting the onset of convection and severe weather. The data can also be used to initialize local numerical weather prediction models. Two operational Doppler Radar systems are in the vicinity of Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS); these systems are operated by the 45th Space Wing (45 SW) and the National Weather Service Melbourne, Fla. (NWS MLB). Dual-Doppler applications were considered by the 45 SW in choosing the site for the new radar. Accordingly, the 45th Weather Squadron (45 WS), NWS MLB and the National Aeronautics and Space Administration tasked the Applied Meteorology Unit (AMU) to investigate the feasibility of establishing dual-Doppler capability using the two existing systems. This study investigated technical, hardware, and software requirements necessary to enable the establishment of a dual-Doppler capability. Review of the available literature pertaining to the dual-Doppler technique and consultation with experts revealed that the physical locations and resulting beam crossing angles of the 45 SW and NWS MLB radars make them ideally suited for a dual-Doppler capability. The dual-Doppler equations were derived to facilitate complete understanding of dual-Doppler synthesis; to determine the technical information requirements; and to determine the components of wind velocity from the equation of continuity and radial velocity data collected by the two Doppler radars. Analysis confirmed the suitability of the existing systems to provide the desired capability. In addition, it is possible that both 45 SW radar data and Terminal Doppler Weather Radar data from Orlando International Airport could be used to alleviate any radar geometry issues at the NWS MLB radar, such as the "cone of silence" or beam blockage. In the event of a radar outage at one of the sites, the multi-radar algorithms would provide continuing coverage of the area through use of the data from the remaining operational radar sites. There are several options to collect, edit, synthesize and display dual-Doppler data sets. These options include commercial packages available for purchase and a variety of freeware packages available from the National Center for Atmospheric Research (NCAR) for processing raw radar data. However, evaluation of the freeware packages revealed that they do not have sufficient documentation and configuration control to be certified for 45 SW use. Additionally, a TI data line must be installed/leased from the NWS MLB office and CCAFS to enable the receipt of NWS MLB raw radar data to use in the dual-Doppler synthesis. Integration of the TI data line into the Eastern Range infrastructure that will meet the security requirements necessary for 45 SW use is time-consuming and costly. Overall evaluation indicates that establishment of the dual-Doppler capability using the existing operational radar systems is desirable and feasible with no technical concerns. Installation of such a system represents a significant enhancement to forecasting capabilities at the 45 WS and at NWS MLB. However, data security and cost considerations must be evaluated in light of current budgetary constraints. In any case, gaining the dual-Doppler capability will provide opportunities for better visualization of the wind field and better forecasting of the onset of convection and severe weather events to support space launch operations at KSC and CCAFS.
Low-loss off-axis feeds for symmetric dual-reflector antennas
NASA Technical Reports Server (NTRS)
Veruttipong, T.; Galindo-Israel, V.; Imbriale, W.
1986-01-01
Circularly symmetric, dual reflector, high gain antenna systems often require feeds placed off the system's axis because of the need for multiple feeds to use the reflector antenna. Also, the constraint requiring the hyperboloid or shaped subreflector to remain circularly symmetric is sometimes added. In a Cassegrainian system, the subreflector and feed may be rotated off axis around the paraboloid focus and retain main reflector focusing. However, substantial spillover results in considerable noise with a high gain/low noise temperature system. In a shaped system, the tilt of the shaped subreflector and feed together results in substantial defocusing as well as spillover noise. If the subreflector is tilted approximately one-half the angle of the feed tilt in either the Cassegrainian or the dual shaped reflector antenna, it is found that spillover and noise are substantially reduced with tolerable defocusing. An extensive numerical analysis of these effects was conducted to determine the characteristics of a planned 70-meter, dual shaped reflector versus Cassegrainian antenna and to gain some understanding of the cause of the observed effects.
Osman, Magda; Stavy, Ruth
2006-12-01
Theories of adult reasoning propose that reasoning consists of two functionally distinct systems that operate under entirely different mechanisms. This theoretical framework has been used to account for a wide range of phenomena, which now encompasses developmental research on reasoning and problem solving. We begin this review by contrasting three main dual-system theories of adult reasoning (Evans & Over, 1996; Sloman, 1996; Stanovich & West, 2000) with a well-established developmental account that also incorporates a dual-system framework (Brainerd & Reyna, 2001). We use developmental studies of the formation and application of intuitive rules in science and mathematics to evaluate the claims that these theories make. Overall, the evidence reviewed suggests that what is crucial to understanding how children reason is the saliency of the features that are presented within a task. By highlighting the importance of saliency as a way of understanding reasoning, we aim to provide clarity concerning the benefits and limitations of adopting a dual-system framework to account for evidence from developmental studies of intuitive reasoning.
Vibration isolation and dual-stage actuation pointing system for space precision payloads
NASA Astrophysics Data System (ADS)
Kong, Yongfang; Huang, Hai
2018-02-01
Pointing and stability requirements for future space missions are becoming more and more stringent. This work follows the pointing control method which consists of a traditional spacecraft attitude control system and a payload active pointing loop, further proposing a vibration isolation and dual-stage actuation pointing system for space precision payloads based on a soft Stewart platform. Central to the concept is using the dual-stage actuator instead of the traditional voice coil motor single-stage actuator to improve the payload active pointing capability. Based on a specified payload, the corresponding platform was designed to be installed between the spacecraft bus and the payload. The performance of the proposed system is demonstrated by preliminary closed-loop control investigations in simulations. With the ordinary spacecraft bus, the line-of-sight pointing accuracy can be controlled to below a few milliarcseconds in tip and tilt. Meanwhile, utilizing the voice coil motor with the softening spring in parallel, which is a portion of the dual-stage actuator, the system effectively achieves low-frequency motion transmission and high-frequency vibration isolation along the other four degree-of-freedom directions.
Toda, Yasunori; Kaku, Wakatake; Tsuruoka, Makoto; Shinogaki, Sho; Abe, Tomoka; Kamiya, Hideaki; Kikuchi, Ayaka; Itoh, Kennosuke; Suga, Hiroyuki
2018-05-04
A dual catalytic system, dirhodium tetrapivalate/ytterbium(III) triflate, enables the three-component reactions of α-alkyl-α-diazoesters, aromatic aldehydes, and N-benzylidenebenzylamine derivatives to afford the corresponding β-amino alcohols in good yields after hydrolysis of the oxazolidine cycloadducts, whereas no β-amino alcohols are obtained in the absence of ytterbium(III) triflate. A similar dual catalytic system, dirhodium tetraacetate/ytterbium(III) triflate, is found to be effective in accelerating the reactions of α-aryl-α-diazoesters in high yields. Furthermore, the reactions using dimethyl diazomalonate are described.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Limborg-Deprey, C
Final dimensions for the LCLS RF gun are described. This gun, referred to as the LCLS gun, is a modified version of the UCLA/BNL/SLAC 1.6 cell S-Band RF gun [1], referred to as the prototype gun. The changes include a larger mode separation (15 MHz for the LCLS gun vs. 3.5 MHz for the prototype gun), a larger radius at the iris between the 2 cells, a reduced surface field on the curvature of the iris between the two cells, Z power coupling, increased cooling channels for operation at 120 Hz, dual rf feed, deformation tuning of the full cell,more » and field probes in both cells. Temporal shaping of the klystron pulse, to reduce the average power dissipated in the gun, has also been adopted. By increasing the mode separation, the amplitude of the 0-mode electric field on the cathode decreases from 10% of the peak on axis field for the prototype gun to less than 3% for the LCLS gun for the steady state fields. Beam performance is improved as shown by the PARMELA simulations. The gun should be designed to accept a future load lock system. Modifications follow the recommendations of our RF review committee [2]. Files and reference documents are compiled in Section IV.« less
Method and system for dual resolution translation stage
Halpin, John Michael
2014-04-22
A dual resolution translation stage includes a stage assembly operable to receive an optical element and a low resolution adjustment device mechanically coupled to the stage assembly. The dual resolution stage also includes an adjustable pivot block mechanically coupled to the stage assembly. The adjustable pivot block includes a pivot shaft. The dual resolution stage further includes a lever arm mechanically coupled to the adjustable pivot block. The lever arm is operable to pivot about the pivot shaft. The dual resolution stage additionally includes a high resolution adjustment device mechanically coupled to the lever arm and the stage assembly.
40 CFR 65.119 - Recordkeeping provisions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... agitators equipped with a dual mechanical seal system that includes barrier fluid system, the owner or... assessment that identifies the representative composition of the process fluid. The assessment shall be based... pump visual inspections as specified in § 65.107(b)(4). (ii) Documentation of dual mechanical seal pump...
WinHPC System Configuration | High-Performance Computing | NREL
CPUs with 48GB of memory. Node 04 has dual Intel Xeon E5530 CPUs with 24GB of memory. Nodes 05-20 have dual AMD Opteron 2374 HE CPUs with 16GB of memory. Nodes 21-30 have been decommissioned. Nodes 31-35 have dual Intel Xeon X5675 CPUs with 48GB of memory. Nodes 36-37 have dual Intel Xeon E5-2680 CPUs with
NASA Technical Reports Server (NTRS)
Jones, Daniel S.; Ruf, Joseph H.; Bui, Trong T.; Martinez, Martel; St. John, Clinton W.
2014-01-01
The dual-bell rocket nozzle was first proposed in 1949, offering a potential improvement in rocket nozzle performance over the conventional-bell nozzle. Despite the performance advantages that have been predicted, both analytically and through static test data, the dual-bell nozzle has still not been adequately tested in a relevant flight environment. In 2013 a proposal was constructed that offered a NASA F-15 airplane as the flight testbed, with the plan to operate a dual-bell rocket nozzle during captive-carried flight. If implemented, this capability will permit nozzle operation into an external flow field similar to that of a launch vehicle, and facilitate an improved understanding of dual-bell nozzle plume sensitivity to external flow-field effects. More importantly, this flight testbed can be utilized to help quantify the performance benefit with the dual-bell nozzle, as well as to advance its technology readiness level. Toward this ultimate goal, this paper provides plans for future flights to quantify the external flow field of the airplane near the nozzle experiment, as well as details on the conceptual design for the dual-bell nozzle cold-flow propellant feed system integration within the NASA F-15 Propulsion Flight Test Fixture. The current study shows that this concept of flight research is feasible, and could result in valuable flight data for the dual-bell nozzle.
A framework for optimizing micro-CT in dual-modality micro-CT/XFCT small-animal imaging system
NASA Astrophysics Data System (ADS)
Vedantham, Srinivasan; Shrestha, Suman; Karellas, Andrew; Cho, Sang Hyun
2017-09-01
Dual-modality Computed Tomography (CT)/X-ray Fluorescence Computed Tomography (XFCT) can be a valuable tool for imaging and quantifying the organ and tissue distribution of small concentrations of high atomic number materials in small-animal system. In this work, the framework for optimizing the micro-CT imaging system component of the dual-modality system is described, either when the micro-CT images are concurrently acquired with XFCT and using the x-ray spectral conditions for XFCT, or when the micro-CT images are acquired sequentially and independently of XFCT. This framework utilizes the cascaded systems analysis for task-specific determination of the detectability index using numerical observer models at a given radiation dose, where the radiation dose is determined using Monte Carlo simulations.
Humoral response to calicivirus in captive tigers given a dual-strain vaccine.
Harrison, Tara M; Harrison, Scott H; Sikarskie, James G; Armstrong, Douglas
2014-03-01
The current feline vaccine with a single strain of calicivirus has been used for captive tigers, yet it may not protect against virulent systemic calicivirus infections. A cross-institutional study investigated the humoral response to a new dual-strain, killed-virus calicivirus vaccine for nine captive tigers. The subspecies of these tigers were Amur (Panthera tigris altaica), Bengal (Panthera tigris tigris), and Malayan (Panthera tigris jacksoni). Serum neutralization titers for virulent feline calicivirus strain FCV-DD1 were higher following dual-strain vaccine administration. There were no reports of adverse vaccine reactions. Dual-strain vaccination may afford broadened cross-protection against different calicivirus strains and is desirable to reduce the risk of virulent systemic calicivirus disease in tigers.
Govender, Mershen; Choonara, Yahya E; van Vuuren, Sandy; Kumar, Pradeep; du Toit, Lisa C; Pillay, Viness
2016-09-01
A delayed-release dual delivery system for amoxicillin and the probiotic Lactobacillus acidophilus was developed and evaluated. Statistical optimization of a cross-linked denatured ovalbumin protective matrix was first synthesized using a Box-Behnken experimental design prior to encapsulation with glyceryl monostereate. The encapsulated ovalbumin matrix was thereafter incorporated with amoxicillin in a gastro-resistant capsule. In vitro characterization and stability analysis of the ovalbumin and encapsulated components were also performed Results: Protection of L. acidophilus probiotic against the bactericidal effects of amoxicillin within the dual formulation was determined. The dual formulation in this study proved effective and provides insight into current microbiome research to identify, classify and use functional healthy bacteria to develop novel probiotic delivery technologies.
NASA Astrophysics Data System (ADS)
Alonso, R.; Villuendas, F.; Borja, J.; Barragán, L. A.; Salinas, I.
2003-05-01
A versatile, low-cost, digital signal processor (DSP) based lock-in module with external reference is described. This module is used to implement an industrial spectrophotometer for measuring spectral transmission and reflection of automotive and architectonic coating glasses over the ultraviolet, visible and near-infrared wavelength range. The light beams are modulated with an optical chopper. A digital phase-locked loop (DPLL) is used to lock the lock-in to the chop frequency. The lock-in rejects the ambient radiation and permits the spectrophotometer to work in the presence of ambient light. The algorithm that implements the dual lock-in and the DPLL in the DSP56002 evaluation module from Motorola is described. The use of a DSP allows implementation of the lock-in and DPLL by software, which gives flexibility and programmability to the system. Lock-in module cost, under 300 euro, is an important parameter taking into account that two modules are used in the system. Besides, the algorithms implemented in this DSP can be directly implemented in the latest DSP generations. The DPLL performance and the spectrophotometer are characterized. Capture and lock DPLL ranges have been measured and checked to be greater than the chop frequency drifts. The lock-in measured frequency response shows that the lock-in performs as theoretically predicted.