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Sample records for dutch elm disease

  1. Elm genetic diversity and hybridization in the presence of Dutch elm disease

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dutch elm disease (DED) has devastated native North American elm species for more than 75 years. The impact of DED on the genetic diversity of one native elm species, U. rubra or slippery elm, is summarized and its potential impact on the genetic diversity of the other four North American native elm...

  2. Birds and Dutch elm disease control

    USGS Publications Warehouse

    DeWitt, J.B.

    1958-01-01

    Brief, factual review of information on effect of DDT and other insecticides on birds. One program for control of elm disease caused 22% decrease in number of adult birds and 56% mortality of nestlings. Quail fed 3 oz. of DDT per ton of food had 16% reduction in young hatched and 500% increase in defective chicks. Quail fed same dosage during winter and breeding seasons had 30% decrease in fertile eggs and 800% increase in defective chicks. More than 90% of their chicks died in first 6 weeks although fed no insecticide. Almost equally bad results came from feeding Pheasants diets with about 1 oz. DDT per ton. Other common insecticides (chlorinated hydrocarbons) also caused lowered chick survival and higher percentages of crippled chicks. From field data we know that 2 lbs. DDT/acre can affect birds and has even worse effects on cold-blooded animals. Efforts to control elm disease have left as much as 196 lbs. DDT/acre in top 3 inches of soil. Earthworms concentrate DDT in their tissues. Thus the treated areas can be traps for birds and other animals. What can be done? 1) In control of elm disease, use minimum effective amount of insecticide; mist blowers use less than sprayers. 2) Avoid applications during migration and nesting seasons. It has been reported that adequate control can be obtained with dormant sprays and that foliar applications may not be required. Tables of this paper show effects of DDT on reproduction of Quail, relative toxicity to quail of 8 insecticides, and amounts of 7 insecticides required to cause 40% or more decrease in Quail reproduction. These comparisons demonstrate that Aldrin, Endrin, and Dieldrin are 20 to 200 times as toxic as DDT and that Heptachlor and Chlordane are only slightly less toxic than Dieldrin. Methoxychlor and Strobane are less toxic to Quail than is DDT.

  3. Leaf trait dissimilarities between Dutch elm hybrids with a contrasting tolerance to Dutch elm disease

    PubMed Central

    Ďurkovič, Jaroslav; Čaňová, Ingrid; Lagaňa, Rastislav; Kučerová, Veronika; Moravčík, Michal; Priwitzer, Tibor; Urban, Josef; Dvořák, Miloň; Krajňáková, Jana

    2013-01-01

    Background and Aims Previous studies have shown that Ophiostoma novo-ulmi, the causative agent of Dutch elm disease (DED), is able to colonize remote areas in infected plants of Ulmus such as the leaf midrib and secondary veins. The objective of this study was to compare the performances in leaf traits between two Dutch elm hybrids ‘Groeneveld’ and ‘Dodoens’ which possess a contrasting tolerance to DED. Trait linkages were also tested with leaf mass per area (LMA) and with the reduced Young's modulus of elasticity (MOE) as a result of structural, developmental or functional linkages. Methods Measurements and comparisons were made of leaf growth traits, primary xylem density components, gas exchange variables and chlorophyll a fluorescence yields between mature plants of ‘Groeneveld’ and ‘Dodoens’ grown under field conditions. A recently developed atomic force microscopy technique, PeakForce quantitative nanomechanical mapping, was used to reveal nanomechanical properties of the cell walls of tracheary elements such as MOE, adhesion and dissipation. Key Results ‘Dodoens’ had significantly higher values for LMA, leaf tissue thickness variables, tracheary element lumen area (A), relative hydraulic conductivity (RC), gas exchange variables and chlorophyll a fluorescence yields. ‘Groeneveld’ had stiffer cell walls of tracheary elements, and higher values for water-use efficiency and leaf water potential. Leaves with a large carbon and nutrient investment in LMA tended to have a greater leaf thickness and a higher net photosynthetic rate, but LMA was independent of RC. Significant linkages were also found between the MOE and some vascular traits such as RC, A and the number of tracheary elements per unit area. Conclusions Strong dissimilarities in leaf trait performances were observed between the examined Dutch elm hybrids. Both hybrids were clearly separated from each other in the multivariate leaf trait space. Leaf growth, vascular and gas

  4. Do mites phoretic on elm bark beetles contribute to the transmission of Dutch elm disease?

    PubMed

    Moser, John C; Konrad, Heino; Blomquist, Stacy R; Kirisits, Thomas

    2010-02-01

    Dutch elm disease (DED) is a destructive vascular wilt disease of elm (Ulmus) trees caused by the introduced Ascomycete fungus Ophiostoma novo-ulmi. In Europe, this DED pathogen is transmitted by elm bark beetles in the genus Scolytus. These insects carry phoretic mites to new, suitable habitats. The aim of this study was to record and quantify conidia and ascospores of O. novo-ulmi on phoretic mites on the three elm bark beetle species Scolytus multistriatus, Scolytus pygmaeus, and Scolytus scolytus. Spores of O. novo-ulmi were found on four of the ten mite species phoretic on Scolytus spp. These included Elattoma fraxini, Proctolaelaps scolyti, Pseudotarsonemoides eccoptogasteri, and Tarsonemus crassus. All four species had spores attached externally to their body surfaces. However, T. crassus carried most spores within its sporothecae, two paired pocket-like structures adapted for fungal transmission. Individuals of Pr. scolyti also had O. novo-ulmi conidia and ascospores frequently in their digestive system, where they may remain viable. While E. fraxini and P. eccoptogasteri rarely had spores attached to their bodies, large portions of Pr. scolyti and T. crassus carried significant numbers of conidia and/or ascospores of O. novo-ulmi. P. scolyti and T. crassus, which likely are fungivores, may thus contribute to the transmission of O. novo-ulmi, by increasing the spore loads of individual Scolytus beetles during their maturation feeding on twigs of healthy elm trees, enhancing the chance for successful infection with the pathogen. Only S. scolytus, which is the most efficient vector of O. novo-ulmi in Europe, carried high numbers of Pr. scolyti and T. crassus, in contrast to S. multistriatus and S. pygmaeus, which are known as less efficient vectors. The high efficiency of S. scolytus in spreading Dutch elm disease may be partly due to its association with these two mites and the hyperphoretic spores of O. novo-ulmi they carry.

  5. Do mites phoretic on elm bark beetles contribute to the transmission of Dutch elm disease?

    NASA Astrophysics Data System (ADS)

    Moser, John C.; Konrad, Heino; Blomquist, Stacy R.; Kirisits, Thomas

    2010-02-01

    Dutch elm disease (DED) is a destructive vascular wilt disease of elm ( Ulmus) trees caused by the introduced Ascomycete fungus Ophiostoma novo-ulmi. In Europe, this DED pathogen is transmitted by elm bark beetles in the genus Scolytus. These insects carry phoretic mites to new, suitable habitats. The aim of this study was to record and quantify conidia and ascospores of O. novo-ulmi on phoretic mites on the three elm bark beetle species Scolytus multistriatus, Scolytus pygmaeus, and Scolytus scolytus. Spores of O. novo-ulmi were found on four of the ten mite species phoretic on Scolytus spp. These included Elattoma fraxini, Proctolaelaps scolyti, Pseudotarsonemoides eccoptogasteri, and Tarsonemus crassus. All four species had spores attached externally to their body surfaces. However, T. crassus carried most spores within its sporothecae, two paired pocket-like structures adapted for fungal transmission. Individuals of Pr. scolyti also had O. novo-ulmi conidia and ascospores frequently in their digestive system, where they may remain viable. While E. fraxini and P. eccoptogasteri rarely had spores attached to their bodies, large portions of Pr. scolyti and T. crassus carried significant numbers of conidia and/or ascospores of O. novo-ulmi. P. scolyti and T. crassus, which likely are fungivores, may thus contribute to the transmission of O. novo-ulmi, by increasing the spore loads of individual Scolytus beetles during their maturation feeding on twigs of healthy elm trees, enhancing the chance for successful infection with the pathogen. Only S. scolytus, which is the most efficient vector of O. novo-ulmi in Europe, carried high numbers of Pr. scolyti and T. crassus, in contrast to S. multistriatus and S. pygmaeus, which are known as less efficient vectors. The high efficiency of S. scolytus in spreading Dutch elm disease may be partly due to its association with these two mites and the hyperphoretic spores of O. novo-ulmi they carry.

  6. Resistance to Dutch Elm Disease Reduces Presence of Xylem Endophytic Fungi in Elms (Ulmus spp.)

    PubMed Central

    Martín, Juan A.; Witzell, Johanna; Blumenstein, Kathrin; Rozpedowska, Elzbieta; Helander, Marjo; Sieber, Thomas N.; Gil, Luis

    2013-01-01

    Efforts to introduce pathogen resistance into landscape tree species by breeding may have unintended consequences for fungal diversity. To address this issue, we compared the frequency and diversity of endophytic fungi and defensive phenolic metabolites in elm (Ulmus spp.) trees with genotypes known to differ in resistance to Dutch elm disease. Our results indicate that resistant U. minor and U. pumila genotypes exhibit a lower frequency and diversity of fungal endophytes in the xylem than susceptible U. minor genotypes. However, resistant and susceptible genotypes showed a similar frequency and diversity of endophytes in the leaves and bark. The resistant and susceptible genotypes could be discriminated on the basis of the phenolic profile of the xylem, but not on basis of phenolics in the leaves or bark. As the Dutch elm disease pathogen develops within xylem tissues, the defensive chemistry of resistant elm genotypes thus appears to be one of the factors that may limit colonization by both the pathogen and endophytes. We discuss a potential trade-off between the benefits of breeding resistance into tree species, versus concomitant losses of fungal endophytes and the ecosystem services they provide. PMID:23468900

  7. Dutch elm disease. (Latest citations from the Life Sciences Collection database). Published Search

    SciTech Connect

    Not Available

    1994-03-01

    The bibliography contains citations concerning the spread and control of Dutch elm disease. Dutch elm disease is a lethal fungal disease in elm trees which is transmitted via bark beetles. Topics included methods to treat the disease and to control the disease-carrying beetle, biochemistry and genetic information on the disease fungus and its phytotoxin, ecological effects of the disease, evidence of fungicide tolerance by the disease fungus, and attempts to breed disease resistant elm trees. Distribution of Dutch elm disease in Iran, Scotland, the United States, Yugoslavia, and Sweden is described. This information is useful, for example, in the development of methods for detection and treatment of Dutch elm disease. (Contains a minimum of 128 citations and includes a subject term index and title list.)

  8. Bird mortality following DDT spray for Dutch elm disease

    USGS Publications Warehouse

    Wurster, D.H.; Wurster, C.F.; Strickland, W.N.

    1965-01-01

    Avian populations in Hanover, N. H., a town that has sprayed its elms with DDT for many years in an attempt to control Dutch elm disease, were compared with those in Norwich, Vt., a town 1 mile (1.6 km) west of Hanover that has never sprayed. Hanover applied 109 lb DDT/acre (2.1 kg/hectare) in April 1963, then used Methoxychlor in April 1964. Population surveys were taken regularly during spring and early summer of these years, dead birds were collected in both towns, and 106 birds were analyzed for DDT, DDE, and DDD. Severe mortality of both resident and migrant birds occurred in Hanover during spring 1963, and the evidence implicates DDT as its cause. Robin loss was estimated at 70% of the resident population, or 350 to 400 individuals, but mortality among other species of widely varied feeding habits was also substantial. Feeding habits suggest that some birds acquired the toxicant by eating living insects carrying DDT, presenting the paradox of survival of the intended DDT victims, and death, instead, of insectivorous birds. Organ and whole bird analyses are presented and criteria for establishing cause of death are discussed. Most of the DDT had been converted to DDE and DDD, and residues were found in all organs analyzed. Robin mortality was reduced, but not eliminated following Methoxychlor application in 1964; these losses were believed caused by residual DDT in the soil. There was no evidence DDT poisoning among other species in 1964, though the dead birds collected were not analyzed.

  9. Host responses and metabolic profiles of wood components in Dutch elm hybrids with a contrasting tolerance to Dutch elm disease

    PubMed Central

    Ďurkovič, Jaroslav; Kačík, František; Olčák, Dušan; Kučerová, Veronika; Krajňáková, Jana

    2014-01-01

    Background and Aims Changes occurring in the macromolecular traits of cell wall components in elm wood following attack by Ophiostoma novo-ulmi, the causative agent of Dutch elm disease (DED), are poorly understood. The purpose of this study was to compare host responses and the metabolic profiles of wood components for two Dutch elm (Ulmus) hybrids, ‘Groeneveld’ (a susceptible clone) and ‘Dodoens’ (a tolerant clone), that have contrasting survival strategies upon infection with the current prevalent strain of DED. Methods Ten-year-old plants of the hybrid elms were inoculated with O. novo-ulmi ssp. americana × novo-ulmi. Measurements were made of the content of main cell wall components and extractives, lignin monomer composition, macromolecular traits of cellulose and neutral saccharide composition. Key Results Upon infection, medium molecular weight macromolecules of cellulose were degraded in both the susceptible and tolerant elm hybrids, resulting in the occurrence of secondary cell wall ruptures and cracks in the vessels, but rarely in the fibres. The 13C nuclear magnetic resonance spectra revealed that loss of crystalline and non-crystalline cellulose regions occurred in parallel. The rate of cellulose degradation was influenced by the syringyl:guaiacyl ratio in lignin. Both hybrids commonly responded to the medium molecular weight cellulose degradation with the biosynthesis of high molecular weight macromolecules of cellulose, resulting in a significant increase in values for the degree of polymerization and polydispersity. Other responses of the hybrids included an increase in lignin content, a decrease in relative proportions of d-glucose, and an increase in proportions of d-xylose. Differential responses between the hybrids were found in the syringyl:guaiacyl ratio in lignin. Conclusions In susceptible ‘Groeneveld’ plants, syringyl-rich lignin provided a far greater degree of protection from cellulose degradation than in ‘Dodoens’, but

  10. Simultaneous induction of jasmonic acid and disease-responsive genes signifies tolerance of American elm to Dutch elm disease

    PubMed Central

    Sherif , S. M.; Shukla, M. R.; Murch, S. J.; Bernier, L.; Saxena, P. K.

    2016-01-01

    Dutch elm disease (DED), caused by three fungal species in the genus Ophiostoma, is the most devastating disease of both native European and North American elm trees. Although many tolerant cultivars have been identified and released, the tolerance mechanisms are not well understood and true resistance has not yet been achieved. Here we show that the expression of disease-responsive genes in reactions leading to tolerance or susceptibility is significantly differentiated within the first 144 hours post-inoculation (hpi). Analysis of the levels of endogenous plant defense molecules such as jasmonic acid (JA) and salicylic acid (SA) in tolerant and susceptible American elm saplings suggested SA and methyl-jasmonate as potential defense response elicitors, which was further confirmed by field observations. However, the tolerant phenotype can be best characterized by a concurrent induction of JA and disease-responsive genes at 96 hpi. Molecular investigations indicated that the expression of fungal genes (i.e. cerato ulmin) was also modulated by endogenous SA and JA and this response was unique among aggressive and non-aggressive fungal strains. The present study not only provides better understanding of tolerance mechanisms to DED, but also represents a first, verified template for examining simultaneous transcriptomic changes during American elm-fungus interactions. PMID:26902398

  11. Bird mortality after spraying for Dutch elm disease with DDT

    USGS Publications Warehouse

    Wurster, C.F.; Wurster, D.H.; Strickland, W.N.

    1965-01-01

    In Hanover, New Hampshire, where elms were sprayed with DDT, 151 dead birds were found; 10 dead birds were found in Norwich, Vermont, where no DDT was used. Chemical analyses of dead birds, observation of symptoms of DDT poisoning, and a population decline after spraying all indicate severe mortality among certain species in Hanover.

  12. Control of yeast-mycelium dimorphism in vitro in Dutch elm disease fungi by manipulation of specific external stimuli.

    PubMed

    Naruzawa, Erika Sayuri; Bernier, Louis

    2014-11-01

    Dutch elm disease (DED) fungi exhibit yeast-mycelium dimorphism both in planta and in vitro. However, previously published data on the transition between these two growth forms in vitro were mostly obtained from a single strain. We examined the effect of six factors on yeast-mycelium dimorphism in vitro in ten strains of Ophiostoma ulmi, Ophiostoma novo-ulmi and Ophiostoma himal-ulmi. Nitrogen sources, calcium, and yeast extract, altogether with inhibitors of phosphodiesterase (caffeine) and dioxygenases (propyl gallate and salicylic acid) were tested in defined culture media. Morphological response to manipulation of several of these factors varied according to the strain of Ophiostoma being analysed. Responses ranged from no statistical differences in morphological transitions to stimulation or reversion of yeast-mycelium dimorphism with the treatments that were tested. These results suggest that different mechanisms and pathways operate in the control of the yeast-mycelium transition in DED pathogens. Oxylipins could be involved in the yeast-to-mycelium transition, since the addition of a dioxygenase inhibitor, salicylic acid, reduced mycelium production in all strains that were tested.

  13. Can vessel dimension explain tolerance toward fungal vascular wilt diseases in woody plants? Lessons from Dutch elm disease and esca disease in grapevine

    PubMed Central

    Pouzoulet, Jérôme; Pivovaroff, Alexandria L.; Santiago, Louis S.; Rolshausen, Philippe E.

    2014-01-01

    This review illuminates key findings in our understanding of grapevine xylem resistance to fungal vascular wilt diseases. Grapevine (Vitis spp.) vascular diseases such as esca, botryosphaeria dieback, and eutypa dieback, are caused by a set of taxonomically unrelated ascomycete fungi. Fungal colonization of the vascular system leads to a decline of the plant host because of a loss of the xylem function and subsequent decrease in hydraulic conductivity. Fungal vascular pathogens use different colonization strategies to invade and kill their host. Vitis vinifera cultivars display different levels of tolerance toward vascular diseases caused by fungi, but the plant defense mechanisms underlying those observations have not been completely elucidated. In this review, we establish a parallel between two vascular diseases, grapevine esca disease and Dutch elm disease, and argue that the former should be viewed as a vascular wilt disease. Plant genotypes exhibit differences in xylem morphology and resistance to fungal pathogens causing vascular wilt diseases. We provide evidence that the susceptibility of three commercial V. vinifera cultivars to esca disease is correlated to large vessel diameter. Additionally, we explore how xylem morphological traits related to water transport are influenced by abiotic factors, and how these might impact host tolerance of vascular wilt fungi. Finally, we explore the utility of this concept for predicting which V. vinifera cultivars are most vulnerable of fungal vascular wilt diseases and propose new strategies for disease management. PMID:24971084

  14. Can vessel dimension explain tolerance toward fungal vascular wilt diseases in woody plants? Lessons from Dutch elm disease and esca disease in grapevine.

    PubMed

    Pouzoulet, Jérôme; Pivovaroff, Alexandria L; Santiago, Louis S; Rolshausen, Philippe E

    2014-01-01

    This review illuminates key findings in our understanding of grapevine xylem resistance to fungal vascular wilt diseases. Grapevine (Vitis spp.) vascular diseases such as esca, botryosphaeria dieback, and eutypa dieback, are caused by a set of taxonomically unrelated ascomycete fungi. Fungal colonization of the vascular system leads to a decline of the plant host because of a loss of the xylem function and subsequent decrease in hydraulic conductivity. Fungal vascular pathogens use different colonization strategies to invade and kill their host. Vitis vinifera cultivars display different levels of tolerance toward vascular diseases caused by fungi, but the plant defense mechanisms underlying those observations have not been completely elucidated. In this review, we establish a parallel between two vascular diseases, grapevine esca disease and Dutch elm disease, and argue that the former should be viewed as a vascular wilt disease. Plant genotypes exhibit differences in xylem morphology and resistance to fungal pathogens causing vascular wilt diseases. We provide evidence that the susceptibility of three commercial V. vinifera cultivars to esca disease is correlated to large vessel diameter. Additionally, we explore how xylem morphological traits related to water transport are influenced by abiotic factors, and how these might impact host tolerance of vascular wilt fungi. Finally, we explore the utility of this concept for predicting which V. vinifera cultivars are most vulnerable of fungal vascular wilt diseases and propose new strategies for disease management.

  15. Massive sequencing of Ulmus minor’s transcriptome provides new molecular tools for a genus under the constant threat of Dutch elm disease

    PubMed Central

    Perdiguero, Pedro; Venturas, Martin; Cervera, María Teresa; Gil, Luis; Collada, Carmen

    2015-01-01

    Elms, especially Ulmus minor and U. americana, are carrying out a hard battle against Dutch elm disease (DED). This vascular wilt disease, caused by Ophiostoma ulmi and O. novo-ulmi, appeared in the twentieth century and killed millions of elms across North America and Europe. Elm breeding and conservation programmes have identified a reduced number of DED tolerant genotypes. In this study, three U. minor genotypes with contrasted levels of tolerance to DED were exposed to several biotic and abiotic stresses in order to (i) obtain a de novo assembled transcriptome of U. minor using 454 pyrosequencing, (ii) perform a functional annotation of the assembled transcriptome, (iii) identify genes potentially involved in the molecular response to environmental stress, and (iv) develop gene-based markers to support breeding programmes. A total of 58,429 putative unigenes were identified after assembly and filtering of the transcriptome. 32,152 of these unigenes showed homology with proteins identified in the genome from the most common plant model species. Well-known family proteins and transcription factors involved in abiotic, biotic or both stresses were identified after functional annotation. A total of 30,693 polymorphisms were identified in 7,125 isotigs, a large number of them corresponding to single nucleotide polymorphisms (SNPs; 27,359). In a subset randomly selected for validation, 87% of the SNPs were confirmed. The material generated may be valuable for future Ulmus gene expression, population genomics and association genetics studies, especially taking into account the scarce molecular information available for this genus and the great impact that DED has on elm populations. PMID:26257751

  16. Functional Annotation of the Ophiostoma novo-ulmi Genome: Insights into the Phytopathogenicity of the Fungal Agent of Dutch Elm Disease

    PubMed Central

    Comeau, André M.; Dufour, Josée; Bouvet, Guillaume F.; Jacobi, Volker; Nigg, Martha; Henrissat, Bernard; Laroche, Jérôme; Levesque, Roger C.; Bernier, Louis

    2015-01-01

    The ascomycete fungus Ophiostoma novo-ulmi is responsible for the pandemic of Dutch elm disease that has been ravaging Europe and North America for 50 years. We proceeded to annotate the genome of the O. novo-ulmi strain H327 that was sequenced in 2012. The 31.784-Mb nuclear genome (50.1% GC) is organized into 8 chromosomes containing a total of 8,640 protein-coding genes that we validated with RNA sequencing analysis. Approximately 53% of these genes have their closest match to Grosmannia clavigera kw1407, followed by 36% in other close Sordariomycetes, 5% in other Pezizomycotina, and surprisingly few (5%) orphans. A relatively small portion (∼3.4%) of the genome is occupied by repeat sequences; however, the mechanism of repeat-induced point mutation appears active in this genome. Approximately 76% of the proteins could be assigned functions using Gene Ontology analysis; we identified 311 carbohydrate-active enzymes, 48 cytochrome P450s, and 1,731 proteins potentially involved in pathogen–host interaction, along with 7 clusters of fungal secondary metabolites. Complementary mating-type locus sequencing, mating tests, and culturing in the presence of elm terpenes were conducted. Our analysis identified a specific genetic arsenal impacting the sexual and vegetative growth, phytopathogenicity, and signaling/plant–defense–degradation relationship between O. novo-ulmi and its elm host and insect vectors. PMID:25539722

  17. Hybridization and introgression between the exotic Siberian elm, Ulmus pumila, and the native Field elm, U. minor, in Italy

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In response to the first Dutch elm disease (DED) pandemic, Siberian elm, Ulmus pumila, was planted to replace the native elm, U. minor, in Italy. The potential for hybridization between these two species is high and repeated hybridization could result in the genetic swamping of the native species an...

  18. Long-term impact of Ophiostoma novo-ulmi on leaf traits and transpiration of branches in the Dutch elm hybrid ‘Dodoens’

    PubMed Central

    Plichta, Roman; Urban, Josef; Gebauer, Roman; Dvořák, Miloň; Ďurkovič, Jaroslav

    2016-01-01

    To better understand the long-term impact of Ophiostoma novo-ulmi Brasier on leaf physiology in ‘Dodoens’, a Dutch elm disease-tolerant hybrid, measurements of leaf area, leaf dry mass, petiole anatomy, petiole hydraulic conductivity, leaf and branch water potential, and branch sap flow were performed 3 years following an initial artificial inoculation. Although fungal hyphae were detected in fully expanded leaves, neither anatomical nor morphological traits were affected, indicating that there was no impact from the fungal hyphae on the leaves during leaf expansion. In contrast, however, infected trees showed both a lower transpiration rate of branches and a lower sap flow density. The long-term persistence of fungal hyphae inside vessels decreased the xylem hydraulic conductivity, but stomatal regulation of transpiration appeared to be unaffected as the leaf water potential in both infected and non-infected trees was similarly driven by the transpirational demands. Regardless of the fungal infection, leaves with a higher leaf mass per area ratio tended to have a higher leaf area-specific conductivity. Smaller leaves had an increased number of conduits with smaller diameters and thicker cell walls. Such a pattern could increase tolerance towards hydraulic dysfunction. Measurements of water potential and theoretical xylem conductivity revealed that petiole anatomy could predict the maximal transpiration rate. Three years following fungal inoculation, phenotypic expressions for the majority of the examined traits revealed a constitutive nature for their possible role in Dutch elm disease tolerance of ‘Dodoens’ trees. PMID:26843210

  19. Long-term impact of Ophiostoma novo-ulmi on leaf traits and transpiration of branches in the Dutch elm hybrid 'Dodoens'.

    PubMed

    Plichta, Roman; Urban, Josef; Gebauer, Roman; Dvořák, Miloň; Ďurkovič, Jaroslav

    2016-03-01

    To better understand the long-term impact of Ophiostoma novo-ulmi Brasier on leaf physiology in 'Dodoens', a Dutch elm disease-tolerant hybrid, measurements of leaf area, leaf dry mass, petiole anatomy, petiole hydraulic conductivity, leaf and branch water potential, and branch sap flow were performed 3 years following an initial artificial inoculation. Although fungal hyphae were detected in fully expanded leaves, neither anatomical nor morphological traits were affected, indicating that there was no impact from the fungal hyphae on the leaves during leaf expansion. In contrast, however, infected trees showed both a lower transpiration rate of branches and a lower sap flow density. The long-term persistence of fungal hyphae inside vessels decreased the xylem hydraulic conductivity, but stomatal regulation of transpiration appeared to be unaffected as the leaf water potential in both infected and non-infected trees was similarly driven by the transpirational demands. Regardless of the fungal infection, leaves with a higher leaf mass per area ratio tended to have a higher leaf area-specific conductivity. Smaller leaves had an increased number of conduits with smaller diameters and thicker cell walls. Such a pattern could increase tolerance towards hydraulic dysfunction. Measurements of water potential and theoretical xylem conductivity revealed that petiole anatomy could predict the maximal transpiration rate. Three years following fungal inoculation, phenotypic expressions for the majority of the examined traits revealed a constitutive nature for their possible role in Dutch elm disease tolerance of 'Dodoens' trees.

  20. How contagious is Dutch disease

    SciTech Connect

    Laney, L.O.

    1982-03-01

    Into the vernacular of economists has come the term Dutch Disease from the Netherland's experience as a net energy exporter. After outlining characterisics of the affliction and the ways in which it can be manifested, this article looks at the economies of United Kingdom, Norway, and Mexico. While the stage of economic development, the structure of the balance of payments, and the exchange-rate regime are at least somewhat different for each, all have economies that are feeling the impact of the energy sector. Common factors are a higher value for the exchange rate than would otherwise be the case and a squeeze on nonenergy sectors of the economy. 4 figures.

  1. Elm leaf beetle performance on ozone-fumigated elm. Forest Service research paper (Final)

    SciTech Connect

    Barger, J.H.; Hall, R.W.; Townsend, A.M.

    1992-01-01

    Leaves (1986) from elm hybrids ('Pioneer', 'Homestead', '970') previously fumigated in open-top chambers with ozone or with charcoal-filtered air (CFA) were evaluated for water and nitrogen content or were fed to adult elm leaf beetles (ELB), Xanthogaleruca = (Pyrrhalta) luteola (Muller), to determine host suitability for beetle fecundity and survivorship. ELB females fed ozone-fumigated leaves laid significantly fewer eggs than females fed CFA-fumigated leaves. Leaf nitrogen or water content was unaffected. Hybrid '970' (1988) was fumigated with CFA or with ozone concentrations to determine effects on ELB fecundity, leaf consumption, and survivorship. Significantly fewer eggs were laid at the higher concentration of ozone. Because higher levels of ozone are found in urban areas and because municipalities often replace American elms, Ulmus americana L., with Dutch elm disease-resistant elm hybrids that are susceptible to ELB defoliation, it is important to explore the relationships between ozone sensitivity of elm and susceptibility to ELB herbivory before recommending replacement use of these elms to municipal arborists. The study was conducted to determine whether ozone pollution influences host quality of elm for ELB and how ELB fecundity, leaf consumption rate, and survivorship are affected.

  2. Trap trees for elm bark beetles : Augmentation with pheromone baits and chlorpyrifos.

    PubMed

    Lanier, G N; Jones, A H

    1985-01-01

    European elm bark beetles,Scolytus multistriatus (Marsh.), were strongly attracted to American elms,Ulmus americana L., baited with theS. multistriatus attractant, multilure, or killed by injection of the arboricide, cacodylic acid; a combination of the two treatments was most attractive. Comparisons of beetle catches on sticky bands affixed to the trees with samples of bark from the same trees showed that the number of beetles landing on cacodylic acid-treated trees was approximately 40 times greater than the number boring into them. Spraying the bark with the insecticide chlorpyrifos had no direct effect on attraction. No live bark beetle brood was found in trees that had been treated with cacodylic acid or chlorpyrifos, but trees that were only baited or left untreated (check) were attacked, killed, and colonized. We suggest that the contribution of the cacodylic acid trap tree technique to Dutch elm disease control will be enhanced by baiting treated trees with multilure and spraying their lower boles with 0.5% chlorpyrifos. This treatment will eliminate diseased and unwanted elms as potential breeding material and kill large numbers of elm bark beetles that might otherwise innoculate healthy elms with the Dutch elm disease fungus.

  3. Conservation of genetic diversity in slippery elm (Ulmus rubra) in Wisconsin despite the devastating impact of Dutch elm disease

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Forest trees tend to be genetically diverse, a condition related to their longevity, outcrossing mating system and extensive gene flow that maintains high levels of genetic diversity within populations. Forest pest epidemics are responsible for many historic and contemporary population declines repo...

  4. PERKINELMER ELM

    EPA Science Inventory

    The PerkinElmer Elm (formerly the AirBase CanarIT) is a multi-sensor air quality monitoring device that measures particulate matter (PM), total volatile organic compounds (VOCs), nitrogen dioxide (NO2), and several other atmospheric components. PM, VOCs, and NO2

  5. Progress and issues in understanding the physics of ELM dynamics, ELM mitigation, and ELM control

    NASA Astrophysics Data System (ADS)

    Oyama, N.

    2008-07-01

    Recent experimental progress in understanding the dynamics of type I ELM, small/no ELM regimes to achieve ELM mitigation and active ELM controls is reviewed. As for the type I ELM dynamics, the smaller growth rate of the ELM precursor relative to the Alfvén frequency, the importance of ELM filaments to evaluate the ELM heat load, the evolution of pedestal pressure in the recovery phase, and the effects of edge toroidal rotation and toroidal field ripple on ELM energy loss have been observed in many devices. In low collisionality (ve*) small/no ELM regimes, the type V ELM has been obtained with one or two filaments in ve*<1 condition. Small normalized ELM energy loss less than 1% has been achieved in the grassy ELM regime in non-rotating plasmas. The highest pedestal pressure has been achieved with smaller edge toroidal rotation counter to the plasma current in the QH-mode. ELM control/suppression by pellet pacing and external magnetic field perturbation has been demonstrated, and so that a design activity of ELM control coils for ITER has started. Various effects of the edge toroidal rotation upon ELM characteristics have been found such as ELM energy loss (ELM frequency) in the type I ELM regime and the grassy ELM regime, changes in edge harmonic oscillation and achievable pedestal pressure in the QH-mode regime, and a screening effect in evaluation of island formation by ELM control coils.

  6. VIEW OF ELM DRIVE FROM ITS INTERSECTION WITH ELM CIRCLE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF ELM DRIVE FROM ITS INTERSECTION WITH ELM CIRCLE. VIEW FACING SOUTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Intersection of Acacia Road and Brich Circle, Pearl City, Honolulu County, HI

  7. Compliance of Disease Awareness Campaigns in Printed Dutch Media with National and International Regulatory Guidelines

    PubMed Central

    Leonardo Alves, Teresa; Martins de Freitas, Auramarina F.; van Eijk, Martine E. C.; Mantel-Teeuwisse, Aukje K.

    2014-01-01

    Background The European legislation prohibits prescription-only medicines' advertising but allows pharmaceutical companies to provide information to the public on health and diseases, provided there is no direct or indirect reference to a pharmaceutical product. Various forms of promotion have become increasingly common in Europe including “disease-oriented” campaigns. Objectives To explore examples of disease awareness campaigns by pharmaceutical companies in the Netherlands, by assessing their compliance with the World Health Organization (WHO) Ethical Criteria for medicinal drug promotion and the Dutch guidelines for provision of information by pharmaceutical companies. Methods Materials referring to health/disease and treatments published in the most widely circulated newspapers and magazines were collected from March to May 2012. An evaluation tool was developed based on relevant underlying principles from the WHO ethical criteria and Dutch self-regulation guidelines. Collected disease awareness advertisements were used to pilot the evaluation tool and to explore the consistency of information provided with the WHO and Dutch criteria. Findings Eighty materials met our inclusion criteria; 71 were published in newspapers and 9 in magazines. The large majority were news items but 21 were disease awareness advertisements, of which 5 were duplicates. Fifteen out of the 16 disease awareness campaigns were non-compliant with current guidelines mainly due to lack of balance (n = 12), absence of listed author and/or sponsor (n = 8), use of misleading or incomplete information (n = 5) and use of promotional information (n = 5). None mentioned a pharmaceutical product directly. Conclusion Disease Awareness Campaigns are present in Dutch printed media. Although no brand names were mentioned, the lack of compliance of disease awareness campaigns with the current regulations is alarming. There were information deficiencies and evidence of information

  8. Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease

    SciTech Connect

    van Duinen, S.G.; Castano, E.M.; Prelli, F.; Bots, G.T.A.B.; Luyendijk, W.; Frangione, B.

    1987-08-01

    Hereditary cerebral hemorrhage with amyloidosis in Dutch patients is an autosomal dominant form of vascular amyloidosis restricted to the leptomeninges and cerebral cortex. Clinically the disease is characterized by cerebral hemorrhages leading to an early death. Immunohistochemical studies of five patients revealed that the vascular amyloid deposits reacted intensely with an antiserum raised against a synthetic peptide homologous to the Alzheimer disease-related ..beta..-protein. Silver stain-positive, senile plaque-like structures were also labeled by the antiserum, yet these lesions lacked the dense amyloid cores present in typical plaques of Alzheimer disease. No neurofibrillary tangles were present. Amyloid fibrils were purified from the leptomeningeal vessels of one patient who clinically had no signs of dementia. The protein had a molecular weight of approx. 4000 and its partial amino acid sequence to position 21 showed homology to the ..beta..-protein of Alzheimer disease and Down syndrome. These results suggest that hereditary cerebral hemorrhage with amyloidosis of Dutch origin is pathogenetically related to Alzheimer disease and support the concept that the initial amyloid deposition in this disorder occurs in the vessel walls before damaging the brain parenchyma. Thus, deposition of ..beta..-protein in brain tissue seems to be related to a spectrum of diseases involving vascular syndromes, progressive dementia, or both.

  9. ELM frequency feedback control on JET

    NASA Astrophysics Data System (ADS)

    Lennholm, M.; Beaumont, P. S.; Carvalho, I. S.; Chapman, I. T.; Felton, R.; Frigione, D.; Garzotti, L.; Goodyear, A.; Graves, J.; Grist, D.; Jachmich, S.; Lang, P.; Lerche, E.; de la Luna, E.; Mooney, R.; Morris, J.; Nave, M. F. F.; Rimini, F.; Sips, G.; Solano, E.; Tsalas, M.; EFDA Contributors, JET

    2015-06-01

    This paper describes the first development and implementation of a closed loop edge localized mode (ELM) frequency controller using gas injection as the actuator. The controller has been extensively used in recent experiments on JET and it has proved to work well at ELM frequencies in the 15-40 Hz range. The controller responds effectively to a variety of disturbances, generally recovering the requested ELM frequency within approximately 500 ms. Controlling the ELM frequency has become of prime importance in the new JET configuration with all metal walls, where insufficient ELM frequency is associated with excessive tungsten influx. The controller has allowed successful operation near the minimum acceptable ELM frequency where the best plasma confinement can be achieved. Use of the ELM frequency controller in conjunction with pellet injection has enabled investigations of ELM triggering by pellets while maintaining the desired ELM frequency even when pellets fail to trigger ELMs.

  10. ELM Studies on DIII--D

    NASA Astrophysics Data System (ADS)

    Osborne, T. H.; Leonard, A. W.; Porter, G. D.

    1996-11-01

    Three classes of Edge Localized Modes, or ELMs, simply labeled Types I, II, and III, in the DIII--D work, are widely observed. Type I ELMs are distinguished by the fact that their frequency increases with increasing input power. A scaling for the Type I ELM energy loss predicts 3% for ITER. The frequency of Type III ELMs decreases with increasing input power. The energy loss per Type III ELM is a factor of 2 to 4 below that for Type I at the same input power. Experiments on DIII--D suggest that proximity to the H--mode threshold power is the critical parameter for Type III ELMs. In contrast to Type I ELMs, the pressure gradient near the separatrix at a Type III ELM is often well below the ideal ballooning mode limit. Medium n magnetic precursor oscillations are observed with Type III ELMs, while no magnetic precursors are observe with Type I ELMs. Type II ELMs have very high frequency and low energy loss compared to Type I ELMs. Type II ELMs do not require low input power in contrast to Type III ELMs. Type II ELMs are associated with edge second stability in combination with either high q or high β_P.

  11. Energy and resource allocation: a dynamic model of the Dutch disease. [Monograph

    SciTech Connect

    Bruno, M.; Sachs, J.

    1982-01-01

    It is well known that a domestic-response discovery gives rise to wealth effects that cause a squeeze of the tradeable-good sector of an open economy. The decline of the manufacturing sector following an energy discovery has been termed the Dutch disease, and has been investigated in many recent studies. The authors' model extends the principally static analyses to date by allowing for: (1) short-run capital specificity and long-run capital mobility; (2) international capital flows; and (3) far-sighted intertemporal optimzing behavior by households and firms. The model is solved by numerical simulation. 9 references, 4 figures, 6 tables.

  12. Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview.

    PubMed

    Roseboom, T J; van der Meulen, J H; Ravelli, A C; Osmond, C; Barker, D J; Bleker, O P

    2001-12-20

    Chronic diseases are the main public health problem in Western countries. There are indications that these diseases originate in the womb. It is thought that undernutrition of the fetus during critical periods of development would lead to adaptations in the structure and physiology of the fetal body, and thereby increase the risk of diseases in later life. The Dutch famine--though a historical disaster--provides a unique opportunity to study effects of undernutrition during gestation in humans. This thesis describes the effects of prenatal exposure to the Dutch famine on health in later life. We found indications that undernutrition during gestation affects health in later life. The effects on undernutrition, however, depend upon its timing during gestation and the organs and systems developing during that critical time window. Furthermore, our findings suggest that maternal malnutrition during gestation may permanently affect adult health without affecting the size of the baby at birth. This may imply that adaptations that enable the fetus to continue to grow may nevertheless have adverse consequences of improved nutrition of pregnant women will be underestimated if these are solely based on the size of the baby at birth. Little is known about what an adequate diet for pregnant women might be. In general, women are especially receptive to advice about diet and lifestyle before and during a pregnancy. This should be exploited to improve the health of future generations.

  13. Alpha-chain disease with involvement of the respiratory tract in a Dutch child

    PubMed Central

    Stoop, J. W.; Ballieux, R. E.; Hijmans, W.; Zegers, B. J. W.

    1971-01-01

    A description is given of an 8-year-old girl of pure Dutch extraction who, since age 4, has shown unclassifiable skin changes, marked eosinophilia and diffuse infiltrative pulmonary changes with enlarged mediastinal lymph glands, dyspnoea and impaired diffusion. The patient's serum contained a large amount of proteins related to the Fc-fragment of IgA. She developed a pharyngeal tumour with the histological characteristics of a paragranuloma. The mucosa of the lower air passages is regarded as a possible site of origin of the abnormal serum protein. The disease was therefore interpreted as a disorder of the secretory IgA system, and this patient could well represent the respiratory form of the alpha-chain disease, described so far. ImagesFig. 3Fig. 4Fig. 5Fig. 1Fig. 2 PMID:4111693

  14. Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage, Dutch Type

    NASA Astrophysics Data System (ADS)

    Levy, Efrat; Carman, Mark D.; Fernandez-Madrid, Ivan J.; Power, Michael D.; Lieberburg, Ivan; van Duinen, Sjoerd G.; Bots, Gerard Th. A. M.; Luyendijk, Willem; Frangione, Blas

    1990-06-01

    An amyloid protein that precipitates in the cerebral vessel walls of Dutch patients with hereditary cerebral hemorrhage with amyloidosis is similar to the amyloid protein in vessel walls and senile plaques in brains of patients with Alzheimer's disease, Down syndrome, and sporadic cerebral amyloid angiopathy. Cloning and sequencing of the two exons that encode the amyloid protein from two patients with this amyloidosis revealed a cytosine-to-guanine transversion, a mutation that caused a single amino acid substitution (glutamine instead of glutamic acid) at position 22 of the amyloid protein. The mutation may account for the deposition of this amyloid protein in the cerebral vessel walls of these patients, leading to cerebral hemorrhages and premature death.

  15. Extinguishing ELMs in detached radiative divertor plasmas

    NASA Astrophysics Data System (ADS)

    Pigarov, Alexander; Krasheninnikov, Sergei; Rognlien, Thomas

    2016-10-01

    In order to avoid deleterious effects of ELMs on PFCs in next-step fusion devices it has been suggested to operate with small-sized ELMs naturally extinguishing in the divertor. Our modeling effort is focusing at extinguishing type-I ELMs: conditions for expelled plasma dissipation; efficiency of ELM power handling by detached radiative divertors; and the ELM impact on detachment state. Here time-dependent modeling of a sequence of many ELMs was performed with 2-D edge plasma transport code UEDGE-MB-W which incorporates the Macro-Blob (MB) approach to simulate non-diffusive filamentary transport and various ``Wall'' (W) models for time-dependent hydrogen wall inventory and recycling. Three cases were modeled, in which extinguishing ELMs are achieved due to: (i) intrinsic impurities via graphite sputtering, (ii) extrinsic impurity gas puff (Ne), and (iii) =(i) +(ii). For each case, we performed a series of UEDGE-MB-W runs scanning the deuterium and impurity inventories, pedestal losses and ELM frequency. Temporal variations of the degree of detachment, ionization front shape, recombination sink strength, radiated fraction, peak power loads, OSP, impurity charge states, and in/out asymmetries were analyzed. We discuss the onset of extinguishing ELMs, conditions for not burning through and enhanced plasma recombination as functions of scanned parameters. Efficiencies of intrinsic and extrinsic impurities in ELM extinguishing are compared.

  16. LETTER: Toroidally asymmetric ELM precursors in TCV

    NASA Astrophysics Data System (ADS)

    Reimerdes, H.; Pochelon, A.; Suttrop, W.

    1998-03-01

    Coherent magnetic oscillations precede edge localized modes (ELMs) in TCV. The precursor has been detected prior to ELMs considered to be of type III and others previously referred to as TCV large ELMs. This permits the identification of both as type III ELMs according to the usual classification scheme. The strong localization of these precursors on the bad curvature side of the plasma and their medium toroidal mode numbers indicate their ballooning character. Unlike conventional MHD modes, these modes start toroidally localized and grow in amplitude and toroidal extent. When the precursor encompasses the whole toroidal circumference, the increased transport phase, as indicated by the characteristic Dα spike, begins.

  17. The polypill in the primary prevention of cardiovascular disease: cost-effectiveness in the Dutch population.

    PubMed

    van Gils, Paul F; Over, Eelco A B; Hamberg-van Reenen, Heleen H; de Wit, G Ardine; van den Berg, Matthijs; Schuit, Albertine J; Engelfriet, Peter M

    2011-01-01

    Objectives The aim of the present study was to estimate the cost-effectiveness of the polypill in the primary prevention of cardiovascular disease. Design A health economic modelling study. Setting Primary healthcare in the Netherlands. Participants Simulated individuals from the general Dutch population, aged 45-75 years. Interventions Opportunistic screening followed by prescription of the polypill to eligible individuals. Eligibility was defined as having a minimum 10-year risk of cardiovascular death as assessed with the Systematic Coronary Risk Evaluation function of alternatively 5%, 7.5% or 10%. Different versions of the polypill were considered, depending on composition: (1) the Indian polycap, with three different types of blood pressure-lowering drugs, a statin and aspirin; (2) as (1) but without aspirin and (3) as (2) but with a double statin dose. In addition, a scenario of (targeted) separate antihypertensive and/or statin medication was simulated. Primary outcome measures Cases of acute myocardial infarction or stroke prevented, quality-adjusted life years (QALYs) gained and the costs per QALY gained. All interventions were compared with usual care. Results All scenarios were cost-effective with an incremental cost-effectiveness ratio between €7900 and 12 300 per QALY compared with usual care. Most health gains were achieved with the polypill without aspirin and containing a double dose of statins. With a 10-year risk of 7.5% as the threshold, this pill would prevent approximately 3.5% of all cardiovascular events. Conclusions Opportunistic screening based on global cardiovascular risk assessment followed by polypill prescription to those with increased risk offers a cost-effective strategy. Most health gain is achieved by the polypill without aspirin and a double statin dose.

  18. The polypill in the primary prevention of cardiovascular disease: cost-effectiveness in the Dutch population

    PubMed Central

    Over, Eelco A B; Hamberg-van Reenen, Heleen H; de Wit, G Ardine; van den Berg, Matthijs; Schuit, Albertine J; Engelfriet, Peter M

    2011-01-01

    Objectives The aim of the present study was to estimate the cost-effectiveness of the polypill in the primary prevention of cardiovascular disease. Design A health economic modelling study. Setting Primary healthcare in the Netherlands. Participants Simulated individuals from the general Dutch population, aged 45–75 years. Interventions Opportunistic screening followed by prescription of the polypill to eligible individuals. Eligibility was defined as having a minimum 10-year risk of cardiovascular death as assessed with the Systematic Coronary Risk Evaluation function of alternatively 5%, 7.5% or 10%. Different versions of the polypill were considered, depending on composition: (1) the Indian polycap, with three different types of blood pressure-lowering drugs, a statin and aspirin; (2) as (1) but without aspirin and (3) as (2) but with a double statin dose. In addition, a scenario of (targeted) separate antihypertensive and/or statin medication was simulated. Primary outcome measures Cases of acute myocardial infarction or stroke prevented, quality-adjusted life years (QALYs) gained and the costs per QALY gained. All interventions were compared with usual care. Results All scenarios were cost-effective with an incremental cost-effectiveness ratio between €7900 and 12 300 per QALY compared with usual care. Most health gains were achieved with the polypill without aspirin and containing a double dose of statins. With a 10-year risk of 7.5% as the threshold, this pill would prevent approximately 3.5% of all cardiovascular events. Conclusions Opportunistic screening based on global cardiovascular risk assessment followed by polypill prescription to those with increased risk offers a cost-effective strategy. Most health gain is achieved by the polypill without aspirin and a double statin dose. PMID:22189351

  19. Discussing sexuality with patients with Parkinson's disease: a survey among Dutch neurologists.

    PubMed

    van Hees, Petra J M; van der Plas, Anton A; van Ek, Gaby F; Putter, Hein; Den Oudsten, Brenda L; den Ouden, Marjolein E M; Elzevier, Henk W

    2017-03-01

    Sexual functioning is often impaired in patients with Parkinson's disease (PD) and may affect quality of life of patients and their spouse. However, little is known about the practice patterns of neurologists with regard to discussing sexuality in this field. The aim of this cross-sectional study was to evaluate to what extent neurologists discuss sexuality with PD patients. A 22-item questionnaire was sent to 139 neurologists specializing in PD. The survey contained questions about their attitudes, knowledge, and practice patterns with respect to sexual dysfunction (SD) in patients with PD. The response rate of the survey was 66.9%. Most participants (56.8%) stated that they address sexuality in less than half of their PD patients. High age of patients (42.0%), insufficient consultation time (37.5%), and a lack of patients' initiative to raise the topic themselves (36.4%) were frequently reported barriers towards discussing sexuality. The majority of participants considered that discussing sexuality is a responsibility that lay with neurologists (85.2%), nurses (73.9%), and patients (72.7%). One quarter of the neurologists reported to have insufficient or no knowledge on SD. The majority of participants regarded screening for SD important or slightly important (85.2%). A large proportion of Dutch neurologists specializing in PD do not routinely discuss sexuality with their PD patients. Sexual healthcare in PD patients may benefit from time-efficient tools and agreements on who is responsible for discussing SD. Furthermore, recommendations in PD guidelines on screening and managing SD should be adapted to fit everyday practice.

  20. Modelling of edge localised modes and edge localised mode control [Modelling of ELMs and ELM control

    SciTech Connect

    Huijsmans, G. T. A.; Chang, C. S.; Ferraro, N.; Sugiyama, L.; Waelbroeck, F.; Xu, X. Q.; Loarte, A.; Futatani, S.

    2015-02-07

    Edge Localised Modes (ELMs) in ITER Q = 10 H-mode plasmas are likely to lead to large transient heat loads to the divertor. In order to avoid an ELM induced reduction of the divertor lifetime, the large ELM energy losses need to be controlled. In ITER, ELM control is foreseen using magnetic field perturbations created by in-vessel coils and the injection of small D2 pellets. ITER plasmas are characterised by low collisionality at a high density (high fraction of the Greenwald density limit). These parameters cannot simultaneously be achieved in current experiments. Thus, the extrapolation of the ELM properties and the requirements for ELM control in ITER relies on the development of validated physics models and numerical simulations. Here, we describe the modelling of ELMs and ELM control methods in ITER. The aim of this paper is not a complete review on the subject of ELM and ELM control modelling but rather to describe the current status and discuss open issues.

  1. Modelling of edge localised modes and edge localised mode control [Modelling of ELMs and ELM control

    DOE PAGES

    Huijsmans, G. T. A.; Chang, C. S.; Ferraro, N.; ...

    2015-02-07

    Edge Localised Modes (ELMs) in ITER Q = 10 H-mode plasmas are likely to lead to large transient heat loads to the divertor. In order to avoid an ELM induced reduction of the divertor lifetime, the large ELM energy losses need to be controlled. In ITER, ELM control is foreseen using magnetic field perturbations created by in-vessel coils and the injection of small D2 pellets. ITER plasmas are characterised by low collisionality at a high density (high fraction of the Greenwald density limit). These parameters cannot simultaneously be achieved in current experiments. Thus, the extrapolation of the ELM properties andmore » the requirements for ELM control in ITER relies on the development of validated physics models and numerical simulations. Here, we describe the modelling of ELMs and ELM control methods in ITER. The aim of this paper is not a complete review on the subject of ELM and ELM control modelling but rather to describe the current status and discuss open issues.« less

  2. Foot-and-Mouth disease control using vaccination: the Dutch experience in 2001.

    PubMed

    Pluimers, F H

    2004-01-01

    A first case of foot-and-mouth disease (FMD) was confirmed on a farm in Oene on 21 March 2001. The Dutch eradication strategy for the area which is densely populated with susceptible animals was immediately applied: stamping out the infected herd and pre-emptive culling of all susceptible animals on farms within a radius of 1 km around an infected farm. If the organisation was unable to cull infected herds within 24 hours after detection and the neighbouring farms within four days, emergency ring vaccination would be applied. By 26 March it was clear that capacity problems prevented the required rapid culling and therefore the decision to apply emergency vaccination was taken. On 28 March vaccination of all susceptible animals was started in 2 km zones around infected farms. In the area where the first outbreak occurred, by 1 April 11 farms were found to be infected. Tracing the links between these infections was difficult, the farms being at a greater distance than 4 km from each other and fear increased that the disease could not be contained in this area. It was therefore decided to vaccinate a larger area: "Vaccination area Noord Veluwe". Suppressive vaccination was chosen. This implied that all vaccinated animals should be killed and destroyed. Vaccination rapidly reduced the number of new infections. In total 26 farms became infected with FMD. The last affected farm was confirmed on 22 April 2001. The last vaccinated animal was culled on 25 May 2001. EU rules also gave the option of choosing protective vaccination. The consequence was that only vaccinated cattle could stay alive. The status 'FMD-free without vaccination' however would then be recovered 12 months after the last outbreak. This consequence was too damaging to the export interests of the country. The killing of healthy vaccinated animals became the predominant factor in the discussion of farmers, politicians and the general public. The need for adjustments in the FMD eradication strategy and in

  3. Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview.

    PubMed

    Roseboom, T J; van der Meulen, J H; Ravelli, A C; Osmond, C; Barker, D J; Bleker, O P

    2001-10-01

    People who were small at birth have been shown to have an increased risk of CHD and chronic bronchitis in later life. These findings have led to the fetal origins hypothesis that proposes that the fetus adapts to a limited supply of nutrients, and in doing so it permanently alters its physiology and metabolism, which could increase its risk of disease in later life. The Dutch famine--though a historical disaster--provides a unique opportunity to study effects of undernutrition during gestation in humans. People who had been exposed to famine in late or mid gestation had reduced glucose tolerance. Whereas people exposed to famine in early gestation had a more atherogenic lipid profile, somewhat higher fibrinogen concentrations and reduced plasma concentrations of factor VII, a higher BMI and they appeared to have a higher risk of CHD. Though the latter was based on small numbers, as could be expected from the relatively young age of the cohort. Nevertheless, this is the first evidence in humans that maternal undernutrition during gestation is linked with the risk of CHD in later life. Our findings broadly support the hypothesis that chronic diseases originate through adaptations made by the fetus in response to undernutrition. The long-term effects of intrauterine undernutrition, however, depend upon its timing during gestation and on the tissues and systems undergoing critical periods of development at that time. Furthermore, our findings suggest that maternal malnutrition during gestation may permanently affect adult health without affecting the size of the baby at birth. This gives the fetal origins hypothesis a new dimension. It may imply that adaptations that enable the fetus to continue to grow may nevertheless have adverse consequences for health in later life. CHD may be viewed as the price paid for successful adaptations to an adverse intra-uterine environment. It also implies that the long-term consequences of improved nutrition of pregnant women will be

  4. Characteristics of ELM precursors on NSTX

    NASA Astrophysics Data System (ADS)

    Ridha, Philipp; Menard, Jonathan; Stutman, Dan

    2005-10-01

    The precursor characteristics of Edge Localized Modes (ELMs) on NSTX were analyzed with Mirnov and USXR diagnostics in terms of toroidal mode number, growth rate, oscillation frequency, growth times before crash, and edge localization. Mode identification is especially difficult for most ELMs studied, as the precursor growth rates are often comparable to the oscillation period. Details of the mode identification process will be described. The Mirnov diagnostic does not tell whether the ELM is edge localized or not, thus the USXR array was used to discriminate between the edge and core plasma using an analysis of the X-ray emission with different metallic filters (Ti 0.4μm - E > 100eV, Be 10μm - E > 500eV, Be 100 μm - E > 1.2keV). Using the titanium filter, a strong correlation between Mirnov and USXR data during an ELM crash was observed. Analysis of the USXR data using a constrained tomographic inversion shows relative USXR fluctuation amplitudes from ELM precursors in the range of 1% to 5%. This analysis combined with an edge displacement model provides an estimate of the transient boundary displacements for typical ELMs of < 5 mm.

  5. Diseases of flounder ( Platichthys Flesus L.) in the Dutch Wadden Sea, and their relation to stress factors

    NASA Astrophysics Data System (ADS)

    Dick Vethaak, A.

    In 1988 a survey was conducted on the occurrence of gross pathologies in flounder ( Platichthys flesus L.) in the Dutch Wadden Sea in relation to stress factors, especially near fresh-water drainage sluices. A total of 9608 flounder were collected from 16 sites in June and September. Diseases recorded were: skin ulcers (affecting 7.7% of fish); fin rot (2.8%; only included in the study in September); lymphocystis (3.7%); skeletal deformities (0.3%); liver nematode infections (5.0%); intestinal cysts of the parasite Glugea sp. (0.4%); and liver nodules (pre-neoplastic and neoplastic lesions) (< 0.1%). Prevalences of skin ulcers and fin rot in Wadden Sea flounder are considerably higher than in those captured off the Dutch North Sea coast or in the Elbe estuary in Germany. These high disease levels in the Wadden Sea, however, are largely due to extremely high prevalences of skin ulcers observed near the drainage sluices of Lake IJssel, indicating a localized effect. Fin rot occurs at relatively high prevalences over the whole study area, but the data should be interpreted with some caution, due to diagnostic problems. Associations with possible disease determinants were investigated and causal hypotheses formulated. In general fish seem to develop skin diseases at sites with strong salinity fluctuations. Nutritional deficiencies possibly related to strong salinity fluctuations, high bacterial loads in the environment and obstacles to fish migration through sluices are amongst the most likely factors determining the locally high levels of skin ulcers. Although not established, it is possible that pollution-related factors and contaminant bioavailability are important. The stress imposed by a combination of these factors may adversely affect the immune system, making the fish vulnerable to opportunistic bacterial infection.

  6. Colloquial Dutch.

    ERIC Educational Resources Information Center

    Bloomfield, Leonard

    This course in colloquial Dutch was originally prepared for use by American Armed Forces personnel who needed to develop a working command of the spoken language in a short period of time. Thirty-one lessons, based on activities common to Dutch culture, are contained in the text. Each lesson provides three parallel columns of sentences: the…

  7. The role of ELM filaments in setting the ELM wetted area in MAST and the implications for future devices

    NASA Astrophysics Data System (ADS)

    Thornton, A. J.; Allan, S. Y.; Dudson, B. D.; Elmore, S. D.; Fishpool, G. M.; Harrison, J. R.; Kirk, A.; The MAST Team; The EUROfusion MST1 Team

    2017-01-01

    The ELM wetted area is a key factor in the peak power load during an ELM, as it sets the region over which the ELM energy is deposited. The deposited heat flux at the target is seen to have striations in the profiles that are generated by the arrival of filaments ejected from the confined plasma. The effect of the filaments arriving at the target on the ELM wetted area, and the relation to the midplane mode number is investigated in this paper using infrared (IR) thermography and high speed visible imaging (>10 kHz). Type I ELMs are analysed, as these have the largest heat fluxes and are observed to have toroidal mode numbers of between 5 and 15. The IR profiles during the ELMs show clear filamentary structures that evolve during the ELM cycle. An increasing number of striations at the target is seen to correspond to an increase in the wetted area. Analysis shows that the ratio of the ELM wetted area to the inter-ELM wetted area, a key parameter for ITER, for the type I ELMs is between 3 and 6 for lower single null plasmas and varies with the ELM midplane mode number, as determined by visible measurements. Monte-Carlo modelling of the ELMs is used to understand the variation seen in the wetted area and the effect of an increased mode number; the modelling replicates the trends seen in the experimental data and supports the observation of increased toroidal mode number generating larger target ELM wetted areas. ITER is thought to be peeling unstable which would imply a lower ELM mode number compared to MAST which is peeling-ballooning unstable. The results of this analysis suggest that the lower n peeling unstable ELMs expected for ITER will have smaller wetted areas than peeling-ballooning unstable ELMs. A smaller wetted area will increase the level of ELM control required, therefore a key prediction required for ITER is the expected ELM mode number.

  8. Solitary magnetic perturbations at the ELM onset

    NASA Astrophysics Data System (ADS)

    Wenninger, R. P.; Zohm, H.; Boom, J. E.; Burckhart, A.; Dunne, M. G.; Dux, R.; Eich, T.; Fischer, R.; Fuchs, C.; Garcia-Munoz, M.; Igochine, V.; Hölzl, M.; Luhmann N., C., Jr.; Lunt, T.; Maraschek, M.; Müller, H. W.; Park, H. K.; Schneider, P. A.; Sommer, F.; Suttrop, W.; Viezzer, E.; the ASDEX Upgrade Team

    2012-11-01

    Tokamak H-mode plasmas frequently exhibit edge-localized modes (ELMs). ELMs allow maintaining sufficient plasma purity and thus enable stationary H-mode. On the other hand in a future device ELMs may cause divertor power flux densities far in excess of tolerable material limits. The size of the energy loss per ELM is determined by saturation effects in the non-linear phase of the ELM, which at present is hardly understood. ASDEX Upgrade is now equipped with a set of fast sampling diagnostics, which is well suited to investigate the chain of events around the ELM crash with appropriate temporal resolution (⩽10 µs). Solitary magnetic perturbations (SMPs) are identified as dominant features in the radial magnetic fluctuations below 100 kHz. They are typically observed close (±100 µs) to the onset of pedestal erosion. SMPs are field aligned structures rotating in the electron diamagnetic drift direction with perpendicular velocities of about 10 km s-1. A comparison of perpendicular velocities suggests that the perturbation evoking SMPs is located at or inside the separatrix. Analysis of very pronounced examples showed that the number of peaks per toroidal turn is 1 or 2, which is clearly lower than the corresponding numbers in linear stability calculations. In combination with strong peaking of the magnetic signals this results in a solitary appearance resembling modes like palm tree modes, edge snakes or outer modes. This behaviour has been quantified as solitariness and correlated with main plasma parameters. SMPs may be considered as a signature of the non-linear ELM phase originating at the separatrix or further inside. Thus they provide a handle to investigate the transition from linear to non-linear ELM phase. By comparison with data from gas puff imaging processes in the non-linear phase at or inside the separatrix and in the scrape-off layer (SOL) can be correlated. A connection between the passing of an SMP and the onset of radial filament propagation has

  9. The global build-up to intrinsic ELM bursts and comparison with pellet triggered ELMs seen in JET

    NASA Astrophysics Data System (ADS)

    Chapman, S. C.; Dendy, R. O.; Lang, P. T.; Watkins, N. W.; Calderon, F. A.; Romanelli, M.; Todd, T. N.; Contributors, JET

    2017-02-01

    We focus on JET plasmas in which ELMs are triggered by pellets in the presence of ELMs which occur naturally. We perform direct time domain analysis of signals from fast radial field coils and toroidal full flux azimuthal loops. These toroidally integrating signals provide simultaneous high time resolution measurements of global plasma dynamics and its coupling to the control system. We examine the time dynamics of these signals in plasmas where pellet injection is used to trigger ELMs in the presence of naturally occurring ELMs. Pellets whose size and speed are intended to provide maximum local perturbation for ELM triggering are launched at pre-programmed times, without correlation to the occurrence times of intrinsic ELMs. Pellet rates were sufficiently low to prevent sustained changes of the underlying plasma conditions and natural ELM behaviour. We find a global signature of the build-up to natural ELMs in the temporal analytic phase of both the full flux loops and fast radial field coil signals. Before a natural ELM, the signal phases align to the same value on a ˜ 2-5 ms timescale. This global build up to a natural ELM occurs whilst the amplitude of the full flux loop and fast radial field coil signals are at their background value: it precedes the response seen in these signals to the onset of ELMing. In contrast these signals do not clearly phase align before the ELM for ELMs which are the first to occur following pellet injection. This provides a direct test that can distinguish when an ELM is triggered by a pellet as opposed to occurring naturally. It further supports the idea [1-4] of a global build up phase that precedes natural ELMs; pellets can trigger ELMs even when the signal phase is at a value when a natural ELM is unlikely to occur.

  10. 1. EXTERIOR VIEW OF ELM CITY PLANT (A. FRANCIS WALKER, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR VIEW OF ELM CITY PLANT (A. FRANCIS WALKER, 1905-07) FROM SECOND AVENUE ON OPPOSITE SIDE OF ENTRANCE. THIS STRUCTURE WAS ORIGINALLY BUILT AS THE ELM CITY COTTON MILL OF CALLAWAY MILLS. NOTE RESERVOIR IN FOREGROUND. THIS PHOTOGRAPH IS THE LEFT SIDE OF A PANORAMA VIEW THAT INCLUDES HAER Nos. GA-128-2 AND GA-128-3. - Elm City Cotton Mill, 1000 Elm Street, La Grange, Troup County, GA

  11. ELM-induced W sputtering sources in JET

    NASA Astrophysics Data System (ADS)

    Brezinsek, S.; den Harder, N.; Guillemaut, C.

    2015-11-01

    JET equipped with Be wall and W divertor showed after one year of operation intact W surfaces at the target plates. Eroded W from both divertor legs contributes to the total W source and content in the plasma. Detailed analysis of the intra-ELM and inter-ELM W source in H-mode discharges has been carried out using spectroscopy of W, D and Be emission and, independently, using ECE and LP to determine respectively the ion impact energies and fluxes to the target plate. The inter-ELM W source can be eliminated in detached conditions due to impact energies below the sputtering threshold, leaving the intra-ELM source to be the dominant one (80%). Comparison between inner and outer divertor showed that both sources are comparable in the intra-ELM phase. Dedicated composition analysis reveals that sputtering by Be ions can account for the residual inter-ELM source, but cannot explain the intra-ELM source due to the low Be concentration in the plasma (1%). D + with energies above 1keV dominate the intra-ELM W sputtering whereas in the inter-ELM phase energies of D + are below the threshold. These energetic ions are transported from the pedestal region to the target plate during ELM excursion. The W source and content as function of the ELM frequency and ion impact energy has been studied for a set of plasmas showing initially a linear increase before decoupling due to ELM-flushing of W from the confined region sets in at about 40Hz. The range of ELM frequencies in JET covers the frequencies predicted for the ITER H-mode baseline scenarios with ELM pacing and detached inter-ELM phase. The W source in ITER will be determined by the intra-ELM phase.

  12. Climate Change and Infectious Disease Risk in Western Europe: A Survey of Dutch Expert Opinion on Adaptation Responses and Actors.

    PubMed

    Akin, Su-Mia; Martens, Pim; Huynen, Maud M T E

    2015-08-18

    There is growing evidence of climate change affecting infectious disease risk in Western Europe. The call for effective adaptation to this challenge becomes increasingly stronger. This paper presents the results of a survey exploring Dutch expert perspectives on adaptation responses to climate change impacts on infectious disease risk in Western Europe. Additionally, the survey explores the expert sample's prioritization of mitigation and adaptation, and expert views on the willingness and capacity of relevant actors to respond to climate change. An integrated view on the causation of infectious disease risk is employed, including multiple (climatic and non-climatic) factors. The results show that the experts consider some adaptation responses as relatively more cost-effective, like fostering interagency and community partnerships, or beneficial to health, such as outbreak investigation and response. Expert opinions converge and diverge for different adaptation responses. Regarding the prioritization of mitigation and adaptation responses expert perspectives converge towards a 50/50 budgetary allocation. The experts consider the national government/health authority as the most capable actor to respond to climate change-induced infectious disease risk. Divergence and consensus among expert opinions can influence adaptation policy processes. Further research is necessary to uncover prevailing expert perspectives and their roots, and compare these.

  13. Climate Change and Infectious Disease Risk in Western Europe: A Survey of Dutch Expert Opinion on Adaptation Responses and Actors

    PubMed Central

    Akin, Su-Mia; Martens, Pim; Huynen, Maud M.T.E.

    2015-01-01

    There is growing evidence of climate change affecting infectious disease risk in Western Europe. The call for effective adaptation to this challenge becomes increasingly stronger. This paper presents the results of a survey exploring Dutch expert perspectives on adaptation responses to climate change impacts on infectious disease risk in Western Europe. Additionally, the survey explores the expert sample’s prioritization of mitigation and adaptation, and expert views on the willingness and capacity of relevant actors to respond to climate change. An integrated view on the causation of infectious disease risk is employed, including multiple (climatic and non-climatic) factors. The results show that the experts consider some adaptation responses as relatively more cost-effective, like fostering interagency and community partnerships, or beneficial to health, such as outbreak investigation and response. Expert opinions converge and diverge for different adaptation responses. Regarding the prioritization of mitigation and adaptation responses expert perspectives converge towards a 50/50 budgetary allocation. The experts consider the national government/health authority as the most capable actor to respond to climate change-induced infectious disease risk. Divergence and consensus among expert opinions can influence adaptation policy processes. Further research is necessary to uncover prevailing expert perspectives and their roots, and compare these. PMID:26295247

  14. 3. RIGHT SIDE OF PANORAMA VIEW OF REAR OF ELM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. RIGHT SIDE OF PANORAMA VIEW OF REAR OF ELM CITY PLANT FROM SECOND AVENUE. NOTE BOILER STACK ON LEFT. THE FULLER E. CALLAWAY MEMORIAL CLOCK TOWER IS THE POINTED STRUCTURE IN THE DISTANCE TO THE RIGHT OF THE TELEPHONE POLE. - Elm City Cotton Mill, 1000 Elm Street, La Grange, Troup County, GA

  15. 2. CENTER PORTION OF PANORAMA VIEW OF REAR OF ELM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. CENTER PORTION OF PANORAMA VIEW OF REAR OF ELM CITY PLANT FROM SECOND AVENUE. NOTE ORIGINAL WATER TANK TOWER IN CENTER AND NEWER ADDITIONS TO THIS STILL OPERATIONAL TEXTILE MILL. - Elm City Cotton Mill, 1000 Elm Street, La Grange, Troup County, GA

  16. Energy loss for grassy ELMs and effects of plasma rotation on the ELM characteristics in JT-60U

    NASA Astrophysics Data System (ADS)

    Oyama, N.; Sakamoto, Y.; Isayama, A.; Takechi, M.; Gohil, P.; Lao, L. L.; Snyder, P. B.; Fujita, T.; Ide, S.; Kamada, Y.; Miura, Y.; Oikawa, T.; Suzuki, T.; Takenaga, H.; Toi, K.; JT-60 Team

    2005-08-01

    The energy loss for grassy edge localized modes (ELMs) has been studied to investigate the applicability of the grassy ELM regime to ITER. The grassy ELM regime is characterized by high frequency periodic collapses of 800-1500 Hz, which is ~15 times faster than that for type I ELMs. The divertor peak heat flux due to grassy ELMs is less than 10% of that for type I ELMs. This smaller heat flux is caused by a narrower radial extent of the collapse of the temperature pedestal. The different radial extent between type I ELMs and grassy ELMs agrees qualitatively with the different radial distribution of the eigenfunctions as determined from ideal MHD stability analysis. The dominant ELM energy loss for grassy ELMs appears to be caused by temperature reduction, and its ratio to the pedestal stored energy was 0.4-1%. This ratio is lower by a factor of about 10 than that for type I ELMs, which typically have between 2-10% fractional loss of the pedestal energy. A systematic study of the effects of counter (CTR) plasma rotation on the ELM characteristics has been performed using a combination of tangential and perpendicular neutral beam injections (NBIs) in JT-60U. In the high plasma triangularity (δ) regime, ELM characteristics (e.g. amplitude, frequency and type) can be changed from type I ELMs to high frequency grassy ELMs as the CTR plasma rotation is increased. On the other hand, in the low δ regime, complete ELM suppression (QH-mode) can be sustained for long periods up to 3.4 s (~18τE or energy confinement times), when the plasma position in terms of the clearance between the first wall and the plasma separatrix is optimized during the application of CTR-NBIs. In JT-60U, a transient QH phase was also observed during the CO-NBI phase with almost no net toroidal rotation at the plasma edge.

  17. ELM experimental study on the EAST Tokamak

    NASA Astrophysics Data System (ADS)

    Liu, Zixi; Gao, Xiang; Xu, Xueqiao; Li, Jiangang; EAST Team

    2013-10-01

    Atypical Type III ELM is observed on EAST tokamak. This type of ELM has MHD precursor and high collisionality at the edge, and also the threshold power is close to the scaling law. But the frequency of the ELM does not decrease with the injected power. Power threshold is lower with the molybdenum wall in double null (DN) on EAST. Considering the effects of the plasma surface (S) to the threshold power, Double Null has the lowest power threshold. Better energy confinement has been observed in DN compared to Single-null (SN) at same power loss. But with the same power loss, Upper Single Null (USN) with the grad-B drift pointing backwards the active X-point (favorable direction) on EAST has the lower energy confinement time than Lower Single Null (LSN). Low Hybrid Wave (LHW) can mitigate ELMs. The power deposition should be near the edge in the H-mode phase. Not only the LHW decreases the max gradient of the density in the pedestal region, but also brings the density oscillations. Low X-point configurations in Lower single null have a lower power threshold. The low X-point discharges on EAST is closer to the DN. Approaching to the DN configuration should be the reason of the lower power threshold caused by the lower X-point on EAST.

  18. ELM structure in the boundary plasma on COMPASS-D

    NASA Astrophysics Data System (ADS)

    Fielding, S. J.; Axon, K. B.; Booth, M. G.; Buttery, R. J.; Dowling, J.; Gates, D.; Hunt, C.; Silva, C.; Valovic, M.

    1997-02-01

    ELM experimental analysis on COMPASS-D, which has previously catalogued magnetic precursor behaviour, has been extended to consider effects in the SOL. ELM precursors are observed at the divertor. Profile changes are measured with high resolution and power and particle losses in ELMs are estimated. High speed videos of an ELM show a turbulent edge extending to the outboard limiter, in broad agreement with reciprocating probe observations. A model which describes well the magnetic features of the ELM, is being extended to include predictions of power deposition structure at the divertor target, for comparison with experimental data.

  19. Statistical physics of inter-ELM time interval sequences

    NASA Astrophysics Data System (ADS)

    Webster, Anthony; Dendy, Richard; Chapman, Sandra; JET-EFDA Team

    2013-10-01

    We report recent studies of the statistical properties of the sequence of time intervals between successive edge localised modes (ELMs). We have compared theoretically derived and empirical probability density functions (pdfs) for the waiting time intervals between ELMs from 85 long steady H-mode plasmas from the Joint European Torus (JET). The Weibull distribution provides a good fit to both type I and type III ELMs, with different parameters. We infer (A J Webster and R O Dendy, Phys Rev Lett 110, 155004 (2013)) that the type III ELMs were generated by a memoryless process, whereas the type I ELMs were consistent with build-up and release. Delay time analysis (F A Calderon, R O Dendy, S C Chapman, A J Webster et al., Phys. Plasmas 20, 042306 (2013)) of six similar JET H-mode plasmas with different levels of gas puffing strongly suggests that the underlying ELMing process is low dimensional. A current study of a dataset of 15,000 ELMs from two weeks of equivalent JET plasmas yields a combined pdf for inter-ELM time intervals which, surprisingly, displays a series of sharp maxima. All three studies show that rigorous statistical analysis of inter-ELM time intervals can contribute to quantitative classification of ELM types and to physical insight into the ELMing processes.

  20. Validation of BOUT++ ELM simulations for the EAST Tokamak discharges

    NASA Astrophysics Data System (ADS)

    Liu, Zixi; Xu, Xueqiao; Gao, Xiang; Liu, Shaocheng; Xia, Tianyang; Xu, Guosheng; Li, Jianggang; EAST Team

    2013-10-01

    EAST ELM experiments validate BOUT++ predictions that low-n modes become dominant at high plasma current, and the bright stripes from visible camera on EAST match ELM filamentary structures of BOUT++ simulations. Four phases of the ELM dynamics including linear growth, nonlinear saturation, pedestal crash, and L-mode-like post-ELM state have been observed in BOUT++ simulations. The simulated radial velocity of ELM explosive event is consistent with the experimental data by Gas Puffing Image (GPI). Energy loss is about 2 percent; more particle and power fluxes are deposited on the outer divertor plate. The small ELMs on EAST are resistive ballooning modes, and higher plasma current and the pressure result in higher growth rate for the lower toroidal numbers. Effect of the diamagnetic drift is stronger than the ballooning instability drive when the pressure gradient increases and the ELM crashes start at the outer mid-plane.

  1. OP-ELM: optimally pruned extreme learning machine.

    PubMed

    Miche, Yoan; Sorjamaa, Antti; Bas, Patrick; Simula, Olli; Jutten, Christian; Lendasse, Amaury

    2010-01-01

    In this brief, the optimally pruned extreme learning machine (OP-ELM) methodology is presented. It is based on the original extreme learning machine (ELM) algorithm with additional steps to make it more robust and generic. The whole methodology is presented in detail and then applied to several regression and classification problems. Results for both computational time and accuracy (mean square error) are compared to the original ELM and to three other widely used methodologies: multilayer perceptron (MLP), support vector machine (SVM), and Gaussian process (GP). As the experiments for both regression and classification illustrate, the proposed OP-ELM methodology performs several orders of magnitude faster than the other algorithms used in this brief, except the original ELM. Despite the simplicity and fast performance, the OP-ELM is still able to maintain an accuracy that is comparable to the performance of the SVM. A toolbox for the OP-ELM is publicly available online.

  2. Transport and MHD simulations of intrinsic and pellet induced ELMs

    NASA Astrophysics Data System (ADS)

    Kim, Ki Min; Na, Yong-Su; Yi, Sumin; Kim, Hyunseok; Kim, Jin Yong

    2010-11-01

    Verification of ELM mechanism and demonstration of ELM control are important issues in current fusion researches targeting ITER and DEMO. This work investigates the physics and operational characteristics of intrinsic and pellet induced ELMs throughout transport simulations using 1.5 D transport codes (C1.5/ASTRA) and MHD simulations using M3D code. Transport simulations are focused on prediction of the global parameters such as ELM energy loss in the type-I ELMy H-mode discharges with and without pellet pace making to examine an applicability of pellet injection for ELM mitigation in KSTAR and ITER. On the other hand, MHD simulations are conducted to explore the physics of intrinsic and pellet induced ELMs by applying the artificial free energy sources of velocity stream and density perturbations on the marginally stable equilibrium, respectively. Similarities and differences of triggering phenomena between intrinsic and pellet induced ELMs are discussed from the MHD approach.

  3. A concept for a decision support system based on practical experiences from a national disease emergency. The Dutch experience.

    PubMed

    Crauwels, A P; de Koning, R; Nielen, M; Elbers, A R; Dijkhuizen, A A; Tielen, M J

    2001-01-01

    In 1997-1998, the Netherlands experienced a large epidemic of classical swine fever (CSF). The magnitude of this epidemic stressed the role information systems could play in supporting the management during an eradication campaign. The enforcement of an eradication strategy can become very complicated, especially with large epidemics, due to time pressure and many different procedures that have to be executed at the same time. The application of comprehensive information systems may result in more control over the process and in a relief of the operational management. After a brief description of the Dutch epidemic the authors provide an overview and the general application of four different types of information systems, classified as decision support systems. The application of these information systems in animal disease control is illustrated by providing concepts for a system architecture for transaction processing, management and executive information support and decision support. The application of a data warehouse as part of this systems architecture is explained. The eradication of CSF from the Netherlands was complicated by several factors. It is important to notice that information systems cannot prevent these factors. However, information systems can support disease control authorities in controlling these factors.

  4. 'A necessary evil that does not "really" cure disease': The domestication of biomedicine by Dutch holistic general practitioners.

    PubMed

    Raaphorst, Nadine; Houtman, Dick

    2016-05-01

    Against the background of studies about the domestication of complementary and alternative medicine into biomedical settings, this article studies how biomedicine is integrated into holistic settings. Data from 19 in-depth interviews with Dutch holistic general practitioners who combine complementary and alternative medicine with conventional treatments demonstrate that they do not believe that conventional biomedicine 'really' cures patients. They feel that it merely suppresses the physical symptoms of a disease, leaving the more fundamental and non-physical causes intact. As a consequence, they use conventional biomedicine for strictly practical and instrumental reasons. This is the case in life-threatening or acute situations, understood as non-physical causes of disease having been left untreated with complementary and alternative medicine for too long. More mundane reasons for its use are the need to take patients' demands for biomedical treatment seriously or to obey authoritative rules, regulations and protocols. The integration of biomedicine into complementary and alternative medicine, then, follows the same logic of domestication of complementary and alternative medicine into biomedicine: it is made subordinate to the prevailing model of health and illness and treated as a practical add-on that does not 'really' cure people.

  5. Rabies in the Dutch East Indies a century ago - a spatio-temporal case study in disease emergence.

    PubMed

    Ward, Michael P

    2014-04-01

    Rabies continues to spread through the Indonesian archipelago. During the past 20 years, several islands - including Flores, Ambon and Bali - that had historically been free of rabies have become infected. However, the Dutch East Indies (a Dutch colony that became modern Indonesia following World War II) had been infected since the 1880s. The spread of rabies is a lesson in the emergence of an infectious disease. Reports of human cases treated for rabies and livestock rabies cases from the 1880s to 1917 were compiled. The spatial and temporal distribution of these cases was analyzed using maps, spatial statistics and time-series techniques. The first confirmed case of rabies was reported in 1889 from the Batavia [Jakarta] district (although disease suspicion was reported as early as 1884). During the 1890s rabies was already commonly reported from Java and the east coast of Sumatra, and by the late 1890s, from Celebes [Sulawesi]. Between 1900 and 1916, cases were reported from other parts of Java, Sumatra and Sulawesi, and from Borneo, the Moluccas and other outlying islands. Between 1897 and 1916, a total of 8826 human cases treated for rabies were reported and between 1908 and 1917, 1033 livestock cases were reported. Most (97.5%) human cases treated were attributed to rabid dogs. Increasing numbers of reports were observed during the period. Between 1908 and 1916 the correlation between human and livestock case reports was 64.2%, and at the district level it was 75.9%. Moderate correlations (>40%) were found between human cases and livestock cases reported up to six months previously. Based on year of first report from each district, human cases were strongly clustered (Moran's autocorrelation 0.47, P=0.005). The most likely spatio-temporal cluster of reported cases of humans treated for rabies originated from the west coast of Sumatra between 1899 and 1905, and other clusters were identified in west Java (1898-1899), the district of Batavia and in east Java

  6. [The Dutch College of General Practitioners' practice guideline 'Parkinson's disease' in summary].

    PubMed

    Draijer, Willem; Eizenga, Wietze H; Sluiter, Alja; Opstelten, Wim; Goudswaard, A N Lex

    2011-01-01

    Parkinson's disease is characterised by bradykinesia in combination with one or more of the following symptoms: rigidity, resting tremor and disorders of posture and balance. Refer a patient with suspected Parkinson's disease (or parkinsonism) for diagnosis and treatment preferably to a neurologist with expertise in movement disorders. The treatment of Parkinson's disease is symptomatic; to date, there is no treatment that slows disease progression. The treatment of patients with Parkinson's disease and its related disorders involves collaboration of the neurologist, Parkinson's disease nurse and general practitioner. In addition to recognizing the hypokinetic-rigid syndrome, the general practitioner has a role in diagnosing and treating associated symptoms and disorders, and in supporting and counseling the patient and their partner or caregiver.

  7. Toward integrated multi-scale simulations for a full ELM cycle with ELM dynamics

    NASA Astrophysics Data System (ADS)

    Xu, Xueqiao

    2015-11-01

    The high-fidelity BOUT + + two-fluid and Gyro-Landau-Fluid code suites have demonstrated significant recent progresses toward integrated multi-scale simulations for a full ELM cycle with ELM dynamics. In order to improve the computational efficiency for a full ELM cycle with ELM dynamics, the basic set of dynamical equations has been separated into equations in the fluctuating and averaged parts over binormal direction. The two parts are advanced together in time but with different time steps, and dynamically exchange the turbulence fluxes and averaged profiles. Nonlinear ELM simulations show three stages of an ELM event: (1) a linear growing phase; (2) a fast crash phase; and (3) a slow inward propagation phase lasting until the core heating flux balances the ELM energy loss and the ELM is terminated. To better understand the inter-ELM pedestal dynamics during the pedestal recovery, BOUT + + simulations started from a kinetic equilibrium reconstruction using measured plasma profiles from DIII-D show that quasi-coherent fluctuations (QCFs) can provide the necessary transport to limit and saturate the H-mode pedestal gradient. The simulations predict that (1) QCFs are localized in the pedestal region as observed on DIII-D; (2) the QCFs are near marginal instability for ideal ballooning modes combined with drift-Alfven wave modes; (3) the dominant mode is around n =15, kθρi = 0.034, comparable to the measured value of 0.04; (4) the frequency of the mode is around 80kHz, close to that of the measured QCF; and (5) particle transport is smaller than the heat transport. BOUT + + simulations have also been performed to elucidate the nature and underlying physics mechanisms of the weakly-quasi-coherent mode (WCM) with higher collisionality, which causes particle transport in I-mode pedestals of Alcator C-Mod. Key simulation results are that (1) there is no ideal peeling-ballooning mode instability for the I-mode studied; (2) a strong instability exists at n >= 20; (3

  8. Making Sense Out of Pulsating Pre-ELM and ELM White Dwarfs

    NASA Astrophysics Data System (ADS)

    Fontaine, G.; Istrate, A.; Gianninas, A.; Brassard, P.; Van Grootel, V.

    2017-03-01

    We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion and rotational mixing. We find that rotational mixing is able to maintain against settling a sufficient amount of helium in the envelope in order to fuel pulsations through He II-He III ionization on the pre-ELM branch of the evolutionary track in the spectroscopic HR diagram. By the time such a low-mass white dwarf enters the ZZ Ceti instability strip on the cooling branch, settling has taken over rotational mixing and produced a pure H envelope. Such a star then pulsates again, but, this time, as a DA white dwarf of the ZZ Ceti type.

  9. ELM behavior in ASDEX Upgrade with and without nitrogen seeding

    NASA Astrophysics Data System (ADS)

    Frassinetti, L.; Dunne, M. G.; Beurskens, M.; Wolfrum, E.; Bogomolov, A.; Carralero, D.; Cavedon, M.; Fischer, R.; Laggner, F. M.; McDermott, R. M.; Meyer, H.; Tardini, G.; Viezzer, E.; the EUROfusion MST1 Team; the ASDEX-Upgrade Team

    2017-02-01

    The Type I ELM behavior in ASDEX Upgrade with full W plasma facing components is studied in terms of time scales and energy losses for a large set of shots characterized by similar operational parameters but different nitrogen seeding rate and input power. ELMs with no nitrogen can have two typical behaviors, that can be classified depending on their duration, the long and the short ELMs. The work shows that both short and long ELMs have a similar first phase, but the long ELMs are characterized by a second phase with further energy losses. The second phase disappears when nitrogen is seeded with a flux rate above 1022 (e s-1). The phenomenon is compatible with a threshold effect. The presence of the second phase is related to a high divertor/scrape-off layer (SOL) temperature and/or to a low pedestal temperature. The ELM energy losses of the two phases are regulated by different mechanisms. The energy losses of the first phase increase with nitrogen which, in turn, produce the increase of the pedestal temperature. So the energy losses of the first phase are regulated by the pedestal top parameters and the increase with nitrogen is due to the decreasing pedestal collisionality. The energy losses of the second phase are related to the divertor/SOL conditions. The long ELMs energy losses increase with increasing divertor temperature and with the number of the expelled filaments. In terms of the power lost by the plasma, the nitrogen seeding increases the power losses of the short ELMs. The long ELMs have a first phase with power losses comparable to the short ELMs losses. Assuming no major difference in the wetted area, these results suggest that (i) the nitrogen might increase the divertor heat fluxes during the short ELMs and that (ii) the long ELMs, despite the longer time scale, are not beneficial in terms of divertor heat loads.

  10. ELM studies on the COMPASS-D tokamak

    NASA Astrophysics Data System (ADS)

    Colton, A. L.; Buttery, R. J.; Fielding, S. J.; Gates, D. A.; Hender, T. C.; Hugill, J.; Morris, A. W.; Valovic, M.; COMPASS-D, the; ECRH Teams

    1996-08-01

    A description of the various ELM types observed in single null divertor plasmas in COMPASS-D is given, including type I and type III ELMs in both ECRH and ohmically heated plasmas. Precursor oscillations to both type I and type III ELMs have been observed. The large variation in the precursor mode structure is discussed, as well as models of the effect on the plasma.

  11. Advances in understanding and utilising ELM control in JET

    NASA Astrophysics Data System (ADS)

    Chapman, I. T.; de la Luna, E.; Lang, P. T.; Liang, Y.; Alper, B.; Denner, P.; Frigione, D.; Garzotti, L.; Ham, C. J.; Huijsmans, G. T. A.; Jachmich, S.; Kocsis, G.; Lennholm, M.; Lupelli, I.; Rimini, F. G.; Sips, A. C. C.; Contributors, JET

    2016-01-01

    Edge localised mode (ELM) control may be essential to develop ITER scenarios with a reasonable lifetime of divertor components, whilst ELM pacing may be essential to develop stationary ITER scenarios with a tungsten divertor. Resonant magnetic perturbations (RMPs) have mitigated ELMs in high collisionality plasmas in JET. The efficacy of RMPs in mitigating the ELMs is found to depend on plasma shaping, with the change in magnetic boundary achieved when non-axisymmetric fields are applied facilitating access to small ELM regimes. The understanding of ELM pacing by vertical kicks or pellets has also been improved in a range of pedestal conditions in JET ({{T}\\text{ped}}=0.7 -1.3 keV) encompassing the ITER-expected domain ({β\\text{N}}=1.4 -2.4, H 98(y, 2)  =  0.8-1.2, {{f}\\text{GW}}˜ 0.7 ). ELM triggering is reliable provided the perturbation is above a threshold which depends on pedestal parameters. ELM triggering is achieved even in the first 10% of the natural ELM cycle suggesting no inherent maximum frequency. At high normalised pressure, the peeling-ballooning modes are stabilised as predicted by ELITE, necessitating a larger perturbation from either kicks or pellets in order to trigger ELMs. Both kicks and pellets have been used to pace ELMs for tungsten flushing. This has allowed stationary plasma conditions with low gas injection in plasmas where the natural ELM frequency is such that it would normally preclude stationary conditions.

  12. Adaptive Online Sequential ELM for Concept Drift Tackling

    PubMed Central

    Basaruddin, Chan

    2016-01-01

    A machine learning method needs to adapt to over time changes in the environment. Such changes are known as concept drift. In this paper, we propose concept drift tackling method as an enhancement of Online Sequential Extreme Learning Machine (OS-ELM) and Constructive Enhancement OS-ELM (CEOS-ELM) by adding adaptive capability for classification and regression problem. The scheme is named as adaptive OS-ELM (AOS-ELM). It is a single classifier scheme that works well to handle real drift, virtual drift, and hybrid drift. The AOS-ELM also works well for sudden drift and recurrent context change type. The scheme is a simple unified method implemented in simple lines of code. We evaluated AOS-ELM on regression and classification problem by using concept drift public data set (SEA and STAGGER) and other public data sets such as MNIST, USPS, and IDS. Experiments show that our method gives higher kappa value compared to the multiclassifier ELM ensemble. Even though AOS-ELM in practice does not need hidden nodes increase, we address some issues related to the increasing of the hidden nodes such as error condition and rank values. We propose taking the rank of the pseudoinverse matrix as an indicator parameter to detect “underfitting” condition. PMID:27594879

  13. Inboard and outboard observations of ELMs on EAST tokamak

    NASA Astrophysics Data System (ADS)

    Yan, Ning; Li, Jie; Xu, Sheng; Chen, Liang

    2016-10-01

    Understanding the edge-localized modes (ELMs) are considered essential for the H-mode operation such as impurity transport and safety of the first wall of future magnetic fusion devices Over last decades, important information on ELMs has been gained from a variety of diagnostics. However, the ELM behavior on high field side is still poorly understood due to less diagnostic there. Recently, two sweeping probes have been set up near inboard mid-plane of EAST tokamak, which provides a unique capability on characterizing the in-out asymmetry of ELMs together with fast reciprocating probe on outboard mid-plane. In our measurements, ELMs are manifested as propagating filaments in the outboard scrape-off layer (SOL). However plasma in the inboard SOL react as density pumping during ELM crash. Two bands of coherent fluctuations preceding ELMs are observed at outboard mid-plane. They are propagating in opposite poloidal direction in the plasma frame The fluctuations saturate before ELM crash, and their frequency alter with pedestal pressure The coherence of higher frequency band fluctuations are significantly reduced on high field side, and plasma appear as broad turbulence instead. These findings can potentially improve our understanding on ELM dynamics.

  14. Sexual behaviour and sexually transmitted diseases in Dutch marines and naval personnel on a United Nations mission in Cambodia.

    PubMed Central

    Hopperus Buma, A P; Veltink, R L; van Ameijden, E J; Tendeloo, C H; Coutinho, R A

    1995-01-01

    OBJECTIVES--To determine the sexual risk behaviour and the incidence of sexually transmitted diseases (STD) among Dutch marines and naval personnel during a United Nations (UN) deployment. METHODS--Surveillance by post deployment questionnaire, administered to 2289 persons in three successive battalions who served for 6 months on a UN deployment in Cambodia during June 1992-November 1993. On site the medical history of all individuals was kept up to date in a database. All personnel received extra education on STD prevention prior to deployment. Condoms were freely obtainable during deployment. RESULTS--1885 persons (82%) handed in the questionnaire of whom 842 (45%) reported to have had sexual contacts with prostitutes or local population. Being younger and single were independent risk factors for having contact. Out of these 842 persons, 750 (89.1%) reported condom use at all times, while 82 (9.7%) reported inconsistent use and 10 persons (1.2%) reported not to have used condoms. Risk factors for inconsistent and non use were being 40 years or older and a higher number of contacts. From the 832 (750 + 82) condom users, 248 (30%) reported condom failure. Risk factors for failure were: inconsistent condom use, having had more than six contacts and being in the second battalion. The patient recording database showed 43 STD cases registered in the total population of 2289 persons (1.9%). CONCLUSIONS--A low STD incidence was found despite a considerable number of reported sexual contacts. The reported condom use was high but the failure rate was considerable and needs further attention. PMID:7635494

  15. Revisiting the Dutch hypothesis.

    PubMed

    Postma, Dirkje S; Weiss, Scott T; van den Berge, Maarten; Kerstjens, Huib A M; Koppelman, Gerard H

    2015-09-01

    The Dutch hypothesis was first articulated in 1961, when many novel and advanced scientific techniques were not available, such as genomics techniques for pinpointing genes, gene expression, lipid and protein profiles, and the microbiome. In addition, computed tomographic scans and advanced analysis techniques to dissect (small) airways disease and emphysema were not available. At that time, the group of researchers under the visionary guidance of Professor N. G. M. Orie put forward that both genetic and environmental factors can determine whether one would have airway obstructive diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Moreover, they stipulated that the phenotype of obstructive airway disease could be affected by sex and changes with aging. Orie and colleagues' call to carefully phenotype patients with obstructive airways diseases has been adopted by many current researchers in an attempt to determine the heterogeneity of both asthma and COPD to better define these diseases and optimize their treatment. The founders of the Dutch hypothesis were far ahead of their time, and we can learn from their insights. We should fully characterize all patients in our clinical practice and not just state that they have asthma, COPD, or asthma and COPD overlap syndrome. This detailed phenotyping can help in understanding these obstructive airway diseases and provide guidance for disease management.

  16. Relationships between fatty liver and fertility and some periparturient diseases in commercial Dutch dairy herds.

    PubMed

    Jorritsma, R; Jorritsma, H; Schukken, Y H; Wentink, G H

    2000-10-15

    Declining fertility in dairy cows is frequently suggested to arise from the occurrence of a more negative energy balance and/or the concomitant increased accumulation of triacylglycerol in the liver. Therefore, we performed a field study to assess the clinical effects of postpartum fatty liver in dairy cows on fertility and reproductive disease. Data were collected from 360 cows from nine dairy herds on fertility, diseases, and the liver triacylglycerol content on two occasions during lactation: 6 to 17 days and 38 to 50 days postpartum. The mean concentration of triacylglycerol in the liver was 54.6 mg/g from 6 to 17 days and 38.4 mg/g from 38 to 50 days postpartum. The probability of pregnancy was 30% lower for cows with higher contents of triacylglycerol in the liver compared to the probability for cows with low liver triacylglycerol (P = 0.049). The probability of estrus was also 35% lower for the cows with high triacylglycerol in the liver. This resulted in larger intervals between parturition and first heat and parturition and pregnancy for these cows. There was no effect observed on the first insemination conception rate. Given a certain level of triacylglycerol, recorded milk production had a positive effect on time to pregnancy. The incidences of endometritis, lochiometra and cystic ovarian follicles were not higher in cows with higher liver triacylglycerol contents. Endometritis was associated with a lower first insemination conception rate and more days open (chi2 = 4.26, P = 0.03 and T-test = -2.02, P= 0.04 respectively). We concluded that our results support the idea that differences in the negative energy balance or the accumulation of triacylglycerol in the liver of postpartum dairy cows affect fertility performance. The data also indicate that an increase in milk production has no negative impact on fertility as long as the amount of triacylglycerol in the liver remains the same.

  17. Investigation of ELMs on Alcator C-Mod

    NASA Astrophysics Data System (ADS)

    Terry, J. L.

    2005-10-01

    C-Mod typically operates in regimes without large ELMs. Recently, discrete ELMs have been routinely produced by making plasmas with large lower triangularity (i.e. >0.75), compared to the more typical C-Mod values <0.6. The ELM character was substantially modified as the triangularity was reduced, changing from discrete ELMs of ˜60 μsec duration, to H-to-L mode back transitions, lasting ˜4msec. The discrete ELMs are most apparent when the density is just above the low-density H-mode threshold, ne˜8x10^19m-3. Pedestal Te up to 1 keV was measured early in the H-mode phase. The spatial structure and propagation of the discrete ELMs are studied using fast-framing (˜250 kHz) cameras and other high resolution optical diagnostics. The magnetics and the optical diagnostics show a rapidly-growing precursor oscillation (100-200 kHz just prior to the ELM crash) that is localized radially to around the top of the pedestal. Outside the LCFS the enhanced emission from the ELM propagates radially outward with a complicated spatial structure, similar in many respects to `blobs.'

  18. A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population.

    PubMed

    Liu, Fan; Arias-Vásquez, Alejandro; Sleegers, Kristel; Aulchenko, Yurii S; Kayser, Manfred; Sanchez-Juan, Pascual; Feng, Bing-Jian; Bertoli-Avella, Aida M; van Swieten, John; Axenovich, Tatiana I; Heutink, Peter; van Broeckhoven, Christine; Oostra, Ben A; van Duijn, Cornelia M

    2007-07-01

    Alzheimer disease (AD) is the most common cause of dementia. We conducted a genome screen of 103 patients with late-onset AD who were ascertained as part of the Genetic Research in Isolated Populations (GRIP) program that is conducted in a recently isolated population from the southwestern area of The Netherlands. All patients and their 170 closely related relatives were genotyped using 402 microsatellite markers. Extensive genealogy information was collected, which resulted in an extremely large and complex pedigree of 4,645 members. The pedigree was split into 35 subpedigrees, to reduce the computational burden of linkage analysis. Simulations aiming to evaluate the effect of pedigree splitting on false-positive probabilities showed that a LOD score of 3.64 corresponds to 5% genomewide type I error. Multipoint analysis revealed four significant and one suggestive linkage peaks. The strongest evidence of linkage was found for chromosome 1q21 (heterogeneity LOD [HLOD]=5.20 at marker D1S498). Approximately 30 cM upstream of this locus, we found another peak at 1q25 (HLOD=4.0 at marker D1S218). These two loci are in a previously established linkage region. We also confirmed the AD locus at 10q22-24 (HLOD=4.15 at marker D10S185). There was significant evidence of linkage of AD to chromosome 3q22-24 (HLOD=4.44 at marker D3S1569). For chromosome 11q24-25, there was suggestive evidence of linkage (HLOD=3.29 at marker D11S1320). We next tested for association between cognitive function and 4,173 single-nucleotide polymorphisms in the linked regions in an independent sample consisting of 197 individuals from the GRIP region. After adjusting for multiple testing, we were able to detect significant associations for cognitive function in four of five AD-linked regions, including the new region on chromosome 3q22-24 and regions 1q25, 10q22-24, and 11q25. With use of cognitive function as an endophenotype of AD, our study indicates the that the RGSL2, RALGPS2, and C1orf49 genes

  19. Dutch audiology.

    PubMed

    Grobben, L M; van Ligtenberg, C L

    1977-01-01

    In the Netherlands audiological care is given at different stages. An attempt is made to screen the hearing of all Dutch babies between the ages of 8 and 12 months. At the age of 4 or over, general audiological care is given by the school medical service; referral is first to a family doctor, who may refer to an otolaryngologist. Curative medical care (examination and therapy) is the province of the family doctor and the otolaryngologist. Otolaryngologists and pediatricians can refer patients to one of 19 Audiological Centers distributed around the country, where a number of workers in different disciplines cooperate for habilitation and rehabilitation. These may include an otolaryngologist in charge, a psychologist, a speech and hearing therapist, an audiologist (usually a physicist or university-trained engineer), social worker, technician, ortho-pedagogue, audiology assistant, and teacher. There are at the moment 25 schools for the hard of hearing and 5 institutes for the deaf. These are often found in conjunction with Audiological Centers, the latter providing paramedical assistance to the pupils by agreement. Finally, the Dutch Organization for Preventive Medicine works to prevent hearing loss in noisy industries.

  20. Construct Validity of the Dutch Version of the 12-Item Partners in Health Scale: Measuring Patient Self-Management Behaviour and Knowledge in Patients with Chronic Obstructive Pulmonary Disease

    PubMed Central

    Lenferink, Anke; Effing, Tanja; Harvey, Peter; Battersby, Malcolm; Frith, Peter; van Beurden, Wendy; van der Palen, Job; Paap, Muirne C. S.

    2016-01-01

    Objective The 12-item Partners in Health scale (PIH) was developed in Australia to measure self-management behaviour and knowledge in patients with chronic diseases, and has undergone several changes. Our aim was to assess the construct validity and reliability of the latest PIH version in Dutch COPD patients. Methods The 12 items of the PIH, scored on a self-rated 9-point Likert scale, are used to calculate total and subscale scores (knowledge; coping; recognition and management of symptoms; and adherence to treatment). We used forward-backward translation of the latest version of the Australian PIH to define a Dutch PIH (PIH(Du)). Mokken Scale Analysis and common Factor Analysis were performed on data from a Dutch COPD sample to investigate the psychometric properties of the Dutch PIH; and to determine whether the four-subscale solution previously found for the original Australian PIH could be replicated for the Dutch PIH. Results Two subscales were found for the Dutch PIH data (n = 118); 1) knowledge and coping; 2) recognition and management of symptoms, adherence to treatment. The correlation between the two Dutch subscales was 0.43. The lower-bound of the reliability of the total scale equalled 0.84. Factor analysis indicated that the first two factors explained a larger percentage of common variance (39.4% and 19.9%) than could be expected when using random data (17.5% and 15.1%). Conclusion We recommend using two PIH subscale scores when assessing self-management in Dutch COPD patients. Our results did not support the four-subscale structure as previously reported for the original Australian PIH. PMID:27564410

  1. Disease prevalence in flounder (Platichthys flesus) from the Dutch Wadden Sea as indicator of environmental quality: A summary of 1988-2005 surveys

    NASA Astrophysics Data System (ADS)

    Vethaak, A. D.

    2013-09-01

    In 1988, epizootics of ulcer disease in the flatfish flounder in the Dutch Wadden Sea were reported near freshwater drainage sluices of IJsselmeer Lake, locally affecting up to 38.9% of fish. Other diseases such as fin rot and lymphocystis were less frequent, but followed a similar pattern. Results of follow-up surveys in the Wadden Sea in 1994-2005 confirm previous findings and also show significantly elevated ulcer prevalences at other smaller drainage works. The most likely stress factors that contributed to the development of the epizootics at these sites include osmotic stress, adverse water quality conditions including chemical contaminants, nutritional deficiencies, and obstruction to fish migration. It was shown that discharges of IJsselmeer Lake freshwater in 1988-96 had a wide effect on the prevalence and distribution of ulcers and lymphocystis in the western Wadden Sea. A general reduction in disease prevalence in flounder in the entire Dutch Wadden Sea was observed during 1988-2005, which was most likely due to a general improvement in water quality and locally improved habitat conditions for flounder near drainage sluices. Ulcer prevalences outside the two IJsselmeer Lake sluices (Den Oever and Kornwerderzand) declined in this period from approximately 30% to 10% for medium-sized fish. Other skin diseases have also displayed a downward trend at both sites in recent years, with prevalences falling sharply to below 1%. Elsewhere in the Wadden Sea and the Ems-Dollard estuary, disease prevalences have declined towards natural background levels (< 1%). It is concluded that skin diseases, especially ulcers, are useful indicators of environmental quality in the Wadden Sea.

  2. Model of ELM suppression by RMPs in DIII-D

    NASA Astrophysics Data System (ADS)

    Callen, J. D.; Nazikian, R.; Ferraro, N. M.; Beidler, M. T.; Hegna, C. C.; La Haye, R. J.; Paz-Soldan, C.

    2016-10-01

    Recent DIII-D experiments explored effects of resonant magnetic perturbations (RMPs) near the minimum applied n=2 RMP amplitude required for ELM suppression in ITER-relevant low collisionality pedestals. Comprehensive tokamak forced magnetic reconnection (FMR) theory is used to describe and quantify the many physical processes involved in stages of RMP effects and an ELM crash response that lead to bifurcation into an ELM-suppressed state: 1) in ELMing equilibrium, flow-screening is strong with little magnetic reconnection; 2) the RMP at q=8/2 penetrates via FMR induced by an ELM crash and locks toroidal flow to the lab frame (like error field mode locking); 3) the ELM crash provides a 8/2 seed island (like NTMs) governed by a modified Rutherford equation; 4) if the total 8/2 RMP is large enough the internal tearing response and flow bifurcate and grow; and 5) flutter transport reduces pedestal top gradients which stabilizes P-B modes and hence suppresses ELMs. This analysis is for discharge 158115 in DIII-D; its potential universality is yet to be determined. Work supported by OFES/DOE under DE-FG02-92ER54139, DE-FG02-86ER53218, DE-AC02-09CH11466 and DE-FC02-04ER54698.

  3. The ELM Survey. VI. Eleven New Double Degenerates

    NASA Astrophysics Data System (ADS)

    Gianninas, A.; Kilic, Mukremin; Brown, Warren R.; Canton, Paul; Kenyon, Scott J.

    2015-10-01

    We present the discovery of 11 new double degenerate systems containing extremely low-mass white dwarfs (ELM WDs). Our radial velocity observations confirm that all of the targets have orbital periods ≤slant 1 day. We perform spectroscopic fits and provide a complete set of physical and binary parameters. We review and compare recent evolutionary calculations and estimate that the systematic uncertainty in our mass determinations due to differences in the evolutionary models is small (≈ 0.01 M⊙). Five of the new systems will merge due to gravitational wave radiation within a Hubble time, bringing the total number of merger systems found in the ELM Survey to 38. We examine the ensemble properties of the current sample of ELM WD binaries, including the period distribution as a function of effective temperature, and the implications for the future evolution of these systems. We also revisit the empirical boundaries of instability strip of ELM WDs and identify new pulsating ELM WD candidates. Finally, we consider the kinematic properties of our sample of ELM WDs and estimate that a significant fraction of the WDs from the ELM Survey are members of the Galactic halo. Based on observations obtained at the MMT Observatory, a joint facility of the Smithsonian Institution and the University of Arizona.

  4. First Observation Of ELM Pacing With Vertical Jogs In A Spherical Torus

    SciTech Connect

    Gerhardt, S P; Canik, J M; Maingi, R; Bell, R; Gates, d; Goldston, R; Hawryluk, R; Le Blanc, B P; Menard, J; Sontag, A C; Sabbagh, S

    2010-07-15

    Experiments in a number of conventional aspect ratio tokamaks have been successful in pacing edge localized modes (ELMs) by rapid vertical jogging of the plasma. This paper demonstrates the first pacing of ELMs in a spherical torus plasma. Applied 30 Hz vertical jogs synchronized the ELMs with the upward motion of the plasma. 45 Hz jogs also lead to an increase in the ELM frequency, though the synchronization of the ELMs and jogs was unclear. A reduction in the ELM energy was observed at the higher driven ELM frequencies. __________________________________________________

  5. 46. VIEW LOOKING EAST FROM THE OLMSTED ELM IN THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. VIEW LOOKING EAST FROM THE OLMSTED ELM IN THE SOUTH LAWN TO THE ROCK GARDEN. (NOTE: HISTORIC ENGLISH YEW ON RIGHT, CRAB APPLE IN CENTER VIEW). - Fairsted, 99 Warren Street, Brookline, Norfolk County, MA

  6. Pheromone Chemistry of the Smaller European Elm Bark Beetle.

    ERIC Educational Resources Information Center

    Beck, Keith

    1978-01-01

    Discusses the aggregation pheromone of the smaller European elm bark beetle, Scolytus multistriatus (Marsham), with emphasis on information that could be used in the classroom as a practical application of organic chemistry. (Author/GA)

  7. VIEW OF ELM DRIVE WITH NORFOLK PINE ON RIGHT. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF ELM DRIVE WITH NORFOLK PINE ON RIGHT. VIEW FACING WEST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Intersection of Acacia Road and Brich Circle, Pearl City, Honolulu County, HI

  8. VIEW OF ELM DRIVE WITH FACILITY 708 ON LEFT. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF ELM DRIVE WITH FACILITY 708 ON LEFT. VIEW FACING EAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Intersection of Acacia Road and Brich Circle, Pearl City, Honolulu County, HI

  9. Comparison of ELM heat loads in snowflake and standard divertors

    SciTech Connect

    Rognlien, T D; Cohen, R H; Ryutov, D D; Umansky, M V

    2012-05-08

    An analysis is given of the impact of the tokamak divertor magnetic structure on the temporal and spatial divertor heat flux from edge localized modes (ELMs). Two configurations are studied: the standard divertor where the poloidal magnetic field (B{sub p}) varies linearly with distance (r) from the magnetic null and the snowflake where B{sub p} varies quadratrically with r. Both one and two-dimensional models are used to analyze the effect of the longer magnetic field length between the midplane and the divertor plate for the snowflake that causes a temporal dilation of the ELM divertor heat flux. A second effect discussed is the appearance of a broad region near the null point where the poloidal plasma beta can substantially exceed unity, especially for the snowflake configuration during the ELM; such a condition is likely to drive additional radial ELM transport.

  10. ELM induced tungsten melting and its impact on tokamak operation

    NASA Astrophysics Data System (ADS)

    Coenen, J. W.; Arnoux, G.; Bazylev, B.; Matthews, G. F.; Jachmich, S.; Balboa, I.; Clever, M.; Dejarnac, R.; Coffey, I.; Corre, Y.; Devaux, S.; Frassinetti, L.; Gauthier, E.; Horacek, J.; Knaup, M.; Komm, M.; Krieger, K.; Marsen, S.; Meigs, A.; Mertens, Ph.; Pitts, R. A.; Puetterich, T.; Rack, M.; Stamp, M.; Sergienko, G.; Tamain, P.; Thompson, V.

    2015-08-01

    In JET-ILW dedicated melt exposures were performed using a sequence of 3MA/2.9T H-Mode JET pulses with an input power of PIN = 23 MW, a stored energy of ∼6 MJ and regular type I ELMs at ΔWELM = 0.3 MJ and fELM ∼ 30 Hz. In order to assess the risk of starting ITER operations with a full W divertor, one of the task was to measure the consequences of W transients melting due to ELMs. JET is the only tokamak able to produce transients/ ELMs large enough (>300 kJ per ELM) to facilitate melting of tungsten. Such ELMs are comparable to mitigated ELMs expected in ITER. By moving the outer strike point (OSP) onto a dedicated leading edge the base temperature was raised within ∼1 s to allow transient ELM-driven melting during the subsequent 0.5 s. Almost 1 mm (∼6 mm3) of W was moved by ∼ 150 ELMs within 5 subsequent discharges. Significant material losses in terms of ejections into the plasma were not observed. There is indirect evidence that some small droplets (∼ 80 μm) were ejected. The impact on the main plasma parameters is minor and no disruptions occurred. The W-melt gradually moved along the lamella edge towards the high field side, driven by j × B forces. The evaporation rate determined is 100 times less than expected from steady state melting and thus only consistent with transient melting during individual ELMs. IR data, spectroscopy, as well as melt modeling point to transient melting. Although the type of damage studied in these JET experiments is unlikely to be experienced in ITER, the results do strongly support the design strategy to avoid exposed edges in the ITER divertor. The JET experiments required a surface at normal incidence and considerable pre-heating to produce tungsten melting. They provide unique experimental evidence for the absence of significant melt splashing at events resembling mitigated ELMs on ITER and establish a unique experimental benchmark for the simulations being used to study transient shallow melting on ITER W

  11. The impact of peeling-ballooning turbulence on ELMs

    NASA Astrophysics Data System (ADS)

    Xi, Pengwei

    2013-10-01

    Although the onset of ELMs has possibly been determined by linear peeling-ballooning (P-B) instabilities and, the nonlinear BOUT + + simulations show that nonlinear mode coupling starts before the onset of ELMs, which can lead to finite amplitude peeling-ballooning (P-B) turbulence at the H-mode pedestal and play a crucial role in ELM dynamics in two aspects: (1) since the P-B turbulence can suppress ELM crash, for a given power input, pedestal can keep evolving to a state with larger pedestal pressure and current gradients. Accordingly, the drives of P-B modes also keep increasing. Therefore the onset of ELM is determined by the competition between linear drive and nonlinear mode coupling. We find that only when a single mode can overcome the nonlinear damping to become dominant, an ELM crash is triggered by this mode. This means with the P-B turbulence, the onset of ELM is determined by a nonlinear criterion γ >γc rather than the previous linear criterion γ > 0 , where γc is the critical growth rate which depends on the P-B turbulence. (2) We find that the P-B turbulence can generate enough self-constant hyper-resistivity needed in ELM simulations when electron inertial is included in Ohm's law. This hyper-resistivity represents anomalous current transport and can set the limit of the narrow current layer width resolved in the simulations. Except the P-B turbulence, the impact of other micro-turbulence, such as KBM turbulence, will be presented via a newly developed electro-magnetic Gyro-Landau-Fluid extension of BOUT + + code. Work was performed for USDOE by LLNL under DE-AC52-07NA27344, LLNL LDRD project 12-ERD-022, and also supported by the NSFC under Grant Nos.10935004, 11261140326.

  12. Improving Diamagnetic Flux Temporal Resolution to Measure ELM Energy Loss

    NASA Astrophysics Data System (ADS)

    Sieck, P. E.; Baylor, L. R.; Evans, T. E.; Leonard, A. W.; Osborne, T. H.; Strait, E. J.

    2010-11-01

    When an ELM occurs in a tokamak, a substantial loss of stored thermal energy can occur in a very short time, resulting in a change in the plasma diamagnetism. A diamagnetic loop is therefore an attractive diagnostic for characterizing the change in energy during ELMs. A loop external to the vessel can be used but it is bandwidth-limited by the vessel wall, therefore the signal is severely attenuated above 40 Hz in DIII-D. The temporal resolution can be improved by combining the (slow) diamagnetic signal with a properly scaled internal (fast) toroidal BT signal. The results agree with finely-spaced EFIT equilibrium reconstructions to within 10% before each ELM, but the diamagnetic calculation often shows up to twice the drop in energy at the ELM. The BT signal reveals the magnetic change completes in 0.5 ms or less with occasional dynamics above 10 kHz. This improved temporal resolution allows comparison of phenomenology in natural vs. pellet-triggered ELMs, and also effects of partial ELM suppression under resonant magnetic perturbation.

  13. Long-term time series prediction using OP-ELM.

    PubMed

    Grigorievskiy, Alexander; Miche, Yoan; Ventelä, Anne-Mari; Séverin, Eric; Lendasse, Amaury

    2014-03-01

    In this paper, an Optimally Pruned Extreme Learning Machine (OP-ELM) is applied to the problem of long-term time series prediction. Three known strategies for the long-term time series prediction i.e. Recursive, Direct and DirRec are considered in combination with OP-ELM and compared with a baseline linear least squares model and Least-Squares Support Vector Machines (LS-SVM). Among these three strategies DirRec is the most time consuming and its usage with nonlinear models like LS-SVM, where several hyperparameters need to be adjusted, leads to relatively heavy computations. It is shown that OP-ELM, being also a nonlinear model, allows reasonable computational time for the DirRec strategy. In all our experiments, except one, OP-ELM with DirRec strategy outperforms the linear model with any strategy. In contrast to the proposed algorithm, LS-SVM behaves unstably without variable selection. It is also shown that there is no superior strategy for OP-ELM: any of three can be the best. In addition, the prediction accuracy of an ensemble of OP-ELM is studied and it is shown that averaging predictions of the ensemble can improve the accuracy (Mean Square Error) dramatically.

  14. [Diagnosis and treatment of gastroesophageal reflux disease in the mentally retarded: guidelines of a multidisciplinary consensus work group. Dutch Association of Physicians in Care of Mentally Handicapped].

    PubMed

    Gimbel, H

    2000-06-10

    Gastroesophageal reflux disease (GORD) is more frequent among people with intellectual disability than among the intellectually normal population. Also GORD is more serious in this population. The diagnosis is often missed, because most intellectually disabled cannot express their complaints of GORD. For that reason a multidisciplinary working group of the Dutch Association of physicians active in the care of persons with a mental handicap has developed guidelines. The working group recommends endoscopy in case of a (alarm) symptoms: haematemesis, prolonged vomiting, irondeficiency anaemia e.c.i., and a 24 hour oesophageal pH test in case of b (aspecific) symptoms: recurrent pneumonia, refusal of food, regurgitation, rumination, dental erosions. In general most patients are cured with drug treatment (omeprazol or another proton pump inhibitor). If symptoms are not improved after 6 months of optimal treatment, surgical treatment may be considered.

  15. Features of spontaneous and pellet-induced ELMs on the HL-2A tokamak

    NASA Astrophysics Data System (ADS)

    Huang, Y.; Liu, C. H.; Nie, L.; Feng, Z.; Ji, X. Q.; Yao, K.; Zhu, G. L.; Liu, Yi; Cui, Z. Y.; Yan, L. W.; Wang, Q. M.; Yang, Q. W.; Ding, X. T.; Dong, J. Q.; Duan, X. R.

    2012-11-01

    The pellet pacing ELM mitigation concept is being tested in some tokamaks such as ASDEX Upgrade, DIII-D and JET. By increasing the ELM frequency, the ELM size can be reduced and eventually suppressed to meet the lifetime requirements on ITER target plates. In the HL-2A tokamak, ELMy H-mode operation is routinely performed and small type-III ELMs with a high repetition rate and some type-I (or possibly large type-III) ELM events are observed. Large ELMs are often preceded by strong coherent magnetic oscillations, and produce obvious perturbations on plasma current Ip, electron density \\bar {n}_{edge} at the edge, stored energy WE, etc. The coherent magnetic oscillations before an ELM crash or during the ELM are measured by toroidal and poloidal Mirnov coils and analysed by the wavelet technique to study the spectral characteristics of the short time ELM events. Pellet injection experiments are performed in type-III ELMy H-mode plasmas and ELM-free H-mode plasmas to study the physics of pellet triggering ELM. The analyses of pellet-induced ELMs and spontaneous ELMs are presented. Because the pellet size is relatively large, it induces magnetic oscillations lasting longer than that of a natural ELM.

  16. Modeling of extinguishing ELMs in detached divertor plasmas

    NASA Astrophysics Data System (ADS)

    Pigarov, A.; Krasheninnikov, S.; Hollmann, E.; Rognlien, T.

    2015-11-01

    Detached plasmas, the primary operational regime for divertors in next-step fusion devices, should be compatible with both good H-mode confinement and relatively small ELMs providing tolerable heat power loads on divertor targets. Here, dynamics of boundary plasma, impurities and material walls over a sequence of many type-I ELM events under detached divertor plasma conditions is studied with UEGDE-MB-W, the newest version of 2D edge plasma transport code, which incorporates Macro-Blob (MB) approach to simulate non-diffusive filamentary transport and various ``Wall'' (W) models for time-dependent hydrogen wall inventory and recycling. We present the results of multi-parametric analysis on the impact of the size and frequency of ELMs on the divertor plasma parameters where we vary the MB characteristics under different pedestals and divertor configurations. We discuss the conditions, under which small but frequent type-I ELMs (typical for high-power H-mode discharges on current tokamaks with hard deuterium gas puff) are not ``burning through'' the formed detached divertor plasma. In this case, the inner and outer divertors are filled by sub-eV, recombining, highly-impure plasma. Variations of impurity plasma content, radiation pattern, and deuterium wall inventory over the ELM cycle are analyzed. UEDGE-MB-W modeling results are compared to available experimental data.

  17. Scaling Relationships for ELM Diverter Heat Flux on DIII D

    NASA Astrophysics Data System (ADS)

    Peters, E. A.; Makowski, M. A.; Leonard, A. W.

    2015-11-01

    Edge Localized Modes (ELMs) are periodic plasma instabilities that occur during H-mode operation in tokamaks. Left unmitigated, these instabilities result in concentrated particle and heat fluxes at the divertor and stand to cause serious damage to the plasma facing components of tokamaks. The purpose of this research is to find scaling relationships that predict divertor heat flux due to ELMs based on plasma parameters at the time of instability. This will be accomplished by correlating characteristic ELM parameters with corresponding plasma measurements and analyzing the data for trends. One early assessment is the effect of the heat transmission coefficient ? on the in/out asymmetry of the calculated ELM heat fluxes. Using IR camera data, further assessments in this study will continue to emphasize in/out asymmetry in ELMs, as this has important implications for ITER operation. Work supported in part by the US DOE, DE-AC52-07NA27344, DE-FC02-04ER54698, Office of Workforce Development for Teachers and Scientists (WDTS) under the Science Undergraduate Laboratory Internships Program (SULI).

  18. Observations of Harmonic Oscillations and ELM Magnetic Precursors in NSTX

    NASA Astrophysics Data System (ADS)

    Kelly, F.; Fredrickson, E.; Bell, R.; Tritz, K.; Maingi, R.; Takahashi, H.

    2010-11-01

    Recent experiments in the National Spherical Torus Experiment (NSTX) demonstrated the progressive suppression of edge localized modes (ELMs) with increasing lithium deposition. Sufficient lithium suppressed ELMs and made the occurrence of low-frequency, low-n harmonics more frequent. Signatures of these harmonic oscillations with a significant edge component were observed in both the high-n Mirnov magnetic and soft X-ray diagnostics of NSTX. Two distinct sets of harmonic oscillations can be observed during some ELM-free periods. The harmonic oscillations are consistent with modes localized in the edge with the frequency of the n = 1 harmonic near the rotation frequency of the edge plasma. NSTX magnetic diagnostics also observe distinctive signatures of ELMs. Transient n = 1 and n = 2 mode bursts and occasional higher n modes with frequency in the 30 to 90 kHz range occurred simultaneous with the increase in fast Da signal. These bursts of n = 1 and n = 2 modes resemble a model simulation of ELMs by T. Evans in which a bifurcation of magnetic topology is driven by nonlinear feedback amplification of thermoelectric currents from linear peeling-ballooning modes.

  19. Stability and ELM Characterization in I-Mode Pedestals

    NASA Astrophysics Data System (ADS)

    Walk, J. R.; Hughes, J. W.; Snyder, P. B.; Hubbard, A. E.; Terry, J. L.; White, A. E.; Whyte, D. G.; Baek, S. G.; Cziegler, I.; Edlund, E.

    2014-10-01

    The I-mode is a novel high-confinement regime explored on Alcator C-Mod, notable for its formation of an H-mode-like temperature pedestal without the accompanying density pedestal, maintaining L-mode particle confinement. I-mode exhibits a number of desirable properties for a reactor regime: among them, it naturally lacks large ELMs, avoiding the need for externally-applied ELM suppression. However, under certain conditions small, intermittent ELM-like events are seen. These events exhibit a range of phenomena in terms of edge and pedestal behavior, particularly for the ELM trigger - the majority of events are synchronized with the sawtooth heat pulse reaching the edge. The stationary pedestal structure is stable against peeling-ballooning MHD as calculated by ELITE in all cases, necessitating treatment of transient pedestal modification to characterize these events. We characterize these ELM events in terms of edge behavior, particularly the modification of the temperature pedestal, edge turbulence and fluctuations, and peeling-ballooning MHD stability. This work is supported by USDoE Award DE-FC02-99ER54512.

  20. Investigation of dynamics of ELM crashes and their mitigation techniques

    SciTech Connect

    Pankin, Alexei Y.

    2015-08-14

    The accurate prediction of H-mode pedestal dynamics is critical for planning experiments in existing tokamaks and in the design of future tokamaks such as ITER and DEMO. The main objective of the proposed research is to advance the understanding of the physics of H-mode pedestal. Through advances in coupled kinetic-MHD simulations, a new model for H-mode pedestal and ELM crashes as well as an improved model for the bootstrap current will be developed. ELMmitigation techniques will also be investigated. The proposed research will help design efficient confinement scenarios and reduce transient heat loads on the divertor and plasma facing components. During the last two years, the principal investigator (PI) of this proposal actively participated in physics studies related to the DOE Joint Research Targets. These studies include the modeling of divertor heat load in the DIII-D, Alcator C-Mod, and NSTX tokamaks in 2010, and the modeling of H-mode pedestal structure in the DIII-D tokamak in 2011. It is proposed that this close collaboration with experimentalists from major US tokamaks continue during the next funding period. Verification and validation will be a strong component of the proposed research. During the course of the project, advances will be made in the following areas; Dynamics of the H-mode pedestal buildup and recovery after ELM crashes – The effects of neutral fueling, particle and thermal pinches will be explored; Dynamics of ELM crashes in realistic tokamak geometries – Heat loads associated with ELM crashes will be validated against experimental measurements. An improved model for ELM crashes will be developed; ELM mitigation – The effect of resonant magnetic perturbations on ELMs stability and their evolution will be investigated; Development of a new bootstrap current model – A reduced model for will be developed through careful verification of existing models for bootstrap current against first-principle kinetic neoclassical simulations

  1. A second case of Gerstmann-Sträussler-Scheinker disease linked to the G131V mutation in the prion protein gene in a Dutch patient.

    PubMed

    Jansen, Casper; Parchi, Piero; Capellari, Sabina; Strammiello, Rosaria; Dopper, Elise G P; van Swieten, John C; Kamphorst, Wouter; Rozemuller, Annemieke J M

    2011-08-01

    A rare case of Gerstmann-Sträussler-Scheinker disease in a 36-year-old Dutch man is reported. The clinical phenotype was characterized by slowly progressive cognitive decline, later followed by ataxia and parkinsonism. Neuropathologic findings consisted of numerous amyloid plaques in the cerebellum, which showed positive staining for the abnormal prion protein (PrP(Sc)). In addition, there were tau accumulations around numerous amyloid deposits in the cerebral cortex, striatum, hippocampal formation, and midbrain. There was no spongiform degeneration. Western blot analysis showed the co-occurrence of 2 distinct abnormal prion protein species comprising an unglycosylated, protease-resistant fragment of approximately 8 kd, which was found to be truncated at both N- and C-terminal ends by epitope mapping, and a detergent-insoluble but protease-sensitive form of full-length PrP(Sc). Sequence analysis disclosed a mutation at codon 131 of the prion protein gene (PRNP), resulting in a valine-for-glycine substitution (G131V). The patient was heterozygous at the polymorphic codon 129 and carried the mutation on the methionine allele. To our knowledge, this is the second family worldwide in which this mutation has been identified. Gerstmann-Sträussler-Scheinker disease should be considered in patients with a clinical diagnosis of familial frontotemporal dementia.

  2. ELM: AN ALGORITHM TO ESTIMATE THE ALPHA ABUNDANCE FROM LOW-RESOLUTION SPECTRA

    SciTech Connect

    Bu, Yude; Zhao, Gang; Kumar, Yerra Bharat; Pan, Jingchang E-mail: gzhao@nao.cas.cn

    2016-01-20

    We have investigated a novel methodology using the extreme learning machine (ELM) algorithm to determine the α abundance of stars. Applying two methods based on the ELM algorithm—ELM+spectra and ELM+Lick indices—to the stellar spectra from the ELODIE database, we measured the α abundance with a precision better than 0.065 dex. By applying these two methods to the spectra with different signal-to-noise ratios (S/Ns) and different resolutions, we found that ELM+spectra is more robust against degraded resolution and ELM+Lick indices is more robust against variation in S/N. To further validate the performance of ELM, we applied ELM+spectra and ELM+Lick indices to SDSS spectra and estimated α abundances with a precision around 0.10 dex, which is comparable to the results given by the SEGUE Stellar Parameter Pipeline. We further applied ELM to the spectra of stars in Galactic globular clusters (M15, M13, M71) and open clusters (NGC 2420, M67, NGC 6791), and results show good agreement with previous studies (within 1σ). A comparison of the ELM with other widely used methods including support vector machine, Gaussian process regression, artificial neural networks, and linear least-squares regression shows that ELM is efficient with computational resources and more accurate than other methods.

  3. ELM: an Algorithm to Estimate the Alpha Abundance from Low-resolution Spectra

    NASA Astrophysics Data System (ADS)

    Bu, Yude; Zhao, Gang; Pan, Jingchang; Bharat Kumar, Yerra

    2016-01-01

    We have investigated a novel methodology using the extreme learning machine (ELM) algorithm to determine the α abundance of stars. Applying two methods based on the ELM algorithm—ELM+spectra and ELM+Lick indices—to the stellar spectra from the ELODIE database, we measured the α abundance with a precision better than 0.065 dex. By applying these two methods to the spectra with different signal-to-noise ratios (S/Ns) and different resolutions, we found that ELM+spectra is more robust against degraded resolution and ELM+Lick indices is more robust against variation in S/N. To further validate the performance of ELM, we applied ELM+spectra and ELM+Lick indices to SDSS spectra and estimated α abundances with a precision around 0.10 dex, which is comparable to the results given by the SEGUE Stellar Parameter Pipeline. We further applied ELM to the spectra of stars in Galactic globular clusters (M15, M13, M71) and open clusters (NGC 2420, M67, NGC 6791), and results show good agreement with previous studies (within 1σ). A comparison of the ELM with other widely used methods including support vector machine, Gaussian process regression, artificial neural networks, and linear least-squares regression shows that ELM is efficient with computational resources and more accurate than other methods.

  4. VizieR Online Data Catalog: The ELM survey. VI. 11 new ELM WD binaries (Gianninas+, 2015)

    NASA Astrophysics Data System (ADS)

    Gianninas, A.; Kilic, M.; Brown, W. R.; Canton, P.; Kenyon, S. J.

    2016-02-01

    We used the 6.5m MMT telescope equipped with the Blue Channel spectrograph, the 200 inch Hale telescope equipped with the Double spectrograph, the Kitt Peak National Observatory 4m telescope equipped with the R-C spectrograph, and more recently with Kitt Peak Ohio State Multi-Object Spectrograph (KOSMOS), to obtain spectroscopy of our 11 targets in several observing runs. We have also been obtaining radial-velocity measurements for candidates from other sources including the Large Sky Area Multi-Object Spectroscopy Telescope (LAMOST). Those 11 new Extremely low-mass white dwarf (ELM WD) binaries bring the total of ELM WDs identified by the ELM Survey up to 73. (4 data files).

  5. ELM-induced transient tungsten melting in the JET divertor

    NASA Astrophysics Data System (ADS)

    Coenen, J. W.; Arnoux, G.; Bazylev, B.; Matthews, G. F.; Autricque, A.; Balboa, I.; Clever, M.; Dejarnac, R.; Coffey, I.; Corre, Y.; Devaux, S.; Frassinetti, L.; Gauthier, E.; Horacek, J.; Jachmich, S.; Komm, M.; Knaup, M.; Krieger, K.; Marsen, S.; Meigs, A.; Mertens, Ph.; Pitts, R. A.; Puetterich, T.; Rack, M.; Stamp, M.; Sergienko, G.; Tamain, P.; Thompson, V.; Contributors, JET-EFDA

    2015-02-01

    The original goals of the JET ITER-like wall included the study of the impact of an all W divertor on plasma operation (Coenen et al 2013 Nucl. Fusion 53 073043) and fuel retention (Brezinsek et al 2013 Nucl. Fusion 53 083023). ITER has recently decided to install a full-tungsten (W) divertor from the start of operations. One of the key inputs required in support of this decision was the study of the possibility of W melting and melt splashing during transients. Damage of this type can lead to modifications of surface topology which could lead to higher disruption frequency or compromise subsequent plasma operation. Although every effort will be made to avoid leading edges, ITER plasma stored energies are sufficient that transients can drive shallow melting on the top surfaces of components. JET is able to produce ELMs large enough to allow access to transient melting in a regime of relevance to ITER. Transient W melt experiments were performed in JET using a dedicated divertor module and a sequence of IP = 3.0 MA/BT = 2.9 T H-mode pulses with an input power of PIN = 23 MW, a stored energy of ˜6 MJ and regular type I ELMs at ΔWELM = 0.3 MJ and fELM ˜ 30 Hz. By moving the outer strike point onto a dedicated leading edge in the W divertor the base temperature was raised within ˜1 s to a level allowing transient, ELM-driven melting during the subsequent 0.5 s. Such ELMs (δW ˜ 300 kJ per ELM) are comparable to mitigated ELMs expected in ITER (Pitts et al 2011 J. Nucl. Mater. 415 (Suppl.) S957-64). Although significant material losses in terms of ejections into the plasma were not observed, there is indirect evidence that some small droplets (˜80 µm) were released. Almost 1 mm (˜6 mm3) of W was moved by ˜150 ELMs within 7 subsequent discharges. The impact on the main plasma parameters was minor and no disruptions occurred. The W-melt gradually moved along the leading edge towards the high-field side, driven by j × B forces. The evaporation rate determined

  6. 75. VIEW LOOKING EAST FROM THE OLMSTED ELM IN THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    75. VIEW LOOKING EAST FROM THE OLMSTED ELM IN THE SOUTH LAWN TO THE ROCK GARDEN. VIEW INCLUDES HISTORIC ENGLISH YEW ON RIGHT, CRAB APPLE IN CENTER. (DUPLICATE OF HABS No. MA-1168-46) - Fairsted, 99 Warren Street, Brookline, Norfolk County, MA

  7. VIEW FROM CENTER OF ELM AVENUE, LOOKING WEST INTO SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW FROM CENTER OF ELM AVENUE, LOOKING WEST INTO SECTION L. AT LEFT STANDS THE PONDEROUS MCDANIEL MAUSOLEUM, WHICH SHOWS THE INFLUENCE OF FRANK FURNESS ON H. Q. FRENCH’S 1887 DESIGN - Woodlands Cemetery, 4000 Woodlands Avenue, Philadelphia, Philadelphia County, PA

  8. VIEW OF PLAYGROUND #4 NEAR ELM CIRCLE, SHOWING PICNIC TABLE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF PLAYGROUND #4 NEAR ELM CIRCLE, SHOWING PICNIC TABLE. VIEW FACING EAST/NORTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Intersection of Acacia Road and Brich Circle, Pearl City, Honolulu County, HI

  9. VIEW OF ELM CIRCLE, FROM BETWEEN FACILITIES 750 AND 750. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF ELM CIRCLE, FROM BETWEEN FACILITIES 750 AND 750. VIEW FACING EAST/NORTHEAST - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Intersection of Acacia Road and Brich Circle, Pearl City, Honolulu County, HI

  10. 65. VIEW OF THE OLMSTED ELM, SOUTH LAWN, AND WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    65. VIEW OF THE OLMSTED ELM, SOUTH LAWN, AND WEST SLOPE. SHOWN IN THE LEFT FOREGROUND ARE THE RESTORED LAWN EDGE AND THE HISTORIC ENGLISH YEW. (DUPLICATE OF HABS No. MA-1168-31) - Fairsted, 99 Warren Street, Brookline, Norfolk County, MA

  11. 67. VIEW FROM BENEATH THE OLMSTED ELM LOOKING TO THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    67. VIEW FROM BENEATH THE OLMSTED ELM LOOKING TO THE SOUTH LAWN AND WEST SLOPE. THERE IS A NEW GRASS BAY ON THE WEST SLOP, SHOWN IN THE BACKGROUND. (DUPLICATE OF HABS No. ma-1168-33) - Fairsted, 99 Warren Street, Brookline, Norfolk County, MA

  12. Intra- and interspecific hybridization in invasive Siberian elm

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Although numerous studies have examined the invasion history of herbaceous plants, few studies have investigated the invasion biology of woody plants. In this study, we determined whether inter-specific hybridization was necessary before invasiveness could evolve in the Siberian elm, Ulmus pumila. P...

  13. Resistance to Antibiotics and Antifungal Medicinal Products: Can Complementary and Alternative Medicine Help Solve the Problem in Common Infection Diseases? The Introduction of a Dutch Research Consortium

    PubMed Central

    Kok, Esther T.; Jong, Miek C.; Gravendeel, Barbara; Van Leeuwen, Willem B.; Baars, Erik W.

    2015-01-01

    The increase of antibiotic resistance worldwide, rising numbers of deaths and costs associated with this, and the fact that hardly any new antimicrobial drugs have been developed during the last decade have increased the interest in Complementary and Alternative Medicine (CAM) therapeutic interventions, if proven safe and effective. Observational studies on clinical CAM practices demonstrate positive effects of treatment of infections with CAM therapies (clinical effects, patient satisfaction) in combination with small percentages of antibiotics prescription. However, Cochrane reviews and other studies demonstrate that in most instances the quality of clinical trials on CAM treatment of infections is currently too low to provide sufficient evidence. Therefore a Dutch consortium on (in vitro and clinical) scientific research on CAM and antibiotic resistance has been formed. The aim and objective of the consortium is to establish an enduring partnership and to develop expertise to further develop and investigate safe and effective CAM treatments for infectious diseases of humans (and animals). A first ongoing project on the development of safe and effective biobased CAM antimycotics in women with (recurrent) vaginal candidiasis infection is introduced. PMID:26539227

  14. Characteristics of type I and type III ELM precursors in ASDEX upgrade

    NASA Astrophysics Data System (ADS)

    Kass, T.; Günter, S.; Maraschek, M.; Suttrop, W.; Zohm, H.; ASDEX Upgrade Team

    1998-01-01

    The temporal evolution of the edge electron pressure gradient during the development of a type I ELM shows that proximity of ∇pedge to the ideal ballooning limit is not sufficient to trigger a type I ELM. Thus, the MHD structure of ELMs is investigated further. The present discussion focuses on the phenomenology of type I and type III ELM precursors. The ELM precursor types are well distinguished by their frequency behaviour and mode structure. The type I ELM precursor oscillation originates from a thin layer close to the plasma edge. For type III ELMs, on the contrary, ∇pedge has a much stronger influence as indicated by their occurrence during L mode.

  15. ELM PARTICLE AND ENERGY TRANSPORT IN THE SOL AND DIVERTOR OF DIII-D

    SciTech Connect

    FENSTERMACHER,ME; LEONARD,AW; SNYDER,PB; BOEDO,JA; COLCHIN,RJ; GROEBNER,RJ; GRAY,DS; GROTH,M; HOLLMANN,E; LASNIER,CJ; OSBORNE,TH; PETRIE,TW; RUDAKOV,DL; TAKAHASHI,H; WATKINS,JG; ZENG,L

    2003-04-01

    A271 ELM PARTICLE AND ENERGY TRANSPORT IN THE SOL AND DIVERTOR OF DIII-D. Results from a series of dedicated experiments measuring the effect of particle and energy pulses from Type-I Edge Localized Modes (ELMs) in the DIII-D scrape-off layer (SOL) and divertor are compared with a simple model of ELM propagation in the boundary plasma. The simple model asserts that the propagation of ELM particle and energy perturbations is dominated by ion parallel convection along SOL fields lines and the recovery from the ELM perturbation is determined by recycling physics. Time scales associated with the initial changes of boundary plasma parameters are expected to be on the order of the ion transit time from the outer midplane, where the ELM instability is initiated, to the divertor targets. To test the model, the ion convection velocity is changed in the experiment by varying the plasma density. At moderate to high density, n{sub e}/n{sub Gr} = 0.5-0.8, the delays in the response of the boundary plasma to the midplane ELM pulses, the density dependence of those delays and other observations are consistent with the model. However, at the lowest densities, n{sub e}/n{sub Gr} {approx} 0.35, small delays between the response sin the two divertors, and changes in the response of the pedestal thermal energy to ELM events, indicate that additional factors including electron conduction in the SOL, the pre-ELM condition of the divertor plasma, and the ratio of ELM instability duration to SOL transit time, may be playing a role. The results show that understanding the response of the SOL and divertor plasmas to ELMs, for various pre-ELM conditions, is just as important to predicting the effect of ELM pulses on the target surfaces of future devices as is predicting the characteristics of the ELM perturbation of the core plasma.

  16. Prevalence and determinants of non-alcoholic fatty liver disease in lifelines: A large Dutch population cohort

    PubMed Central

    Schreuder, Tim C. M. A.; Dullaart, Robin P. F.; Faber, Klaas Nico; Alizadeh, Behrooz Z.; Blokzijl, Hans

    2017-01-01

    Background & aims Non-alcoholic fatty liver disease is an increasing health issue that develops rather unnoticed with obesity, type 2 diabetes mellitus and metabolic syndrome. We investigated prevalence, determinants and associated metabolic abnormalities of non-alcoholic fatty liver disease in the largest population-based cohort to date. Methods Biochemical characteristics, type 2 diabetes mellitus and metabolic syndrome were determined in the Lifelines Cohort Study (N = 167,729), a population-based cohort in the North of the Netherlands. Non-alcoholic fatty liver disease was defined as Fatty Liver Index (FLI)≥60. Exclusion criteria were age <18 years, immigrants, missing data to assess FLI and metabolic syndrome, excessive alcohol use, previous-diagnosed hepatitis or cirrhosis and non-fasting blood sampling. Results Out of 37,496 included participants (median age 44 years, 62.1% female), 8,259 (22.0%) had a FLI≥60. Individuals with a FLI≥60 were more often male, older, obese, had higher levels of hemoglobinA1c, fasting glucose, liver enzymes, total cholesterol, low-density lipoprotein cholesterol, triglycerides, c-reactive protein and leucocytes and lower high-density lipoprotein cholesterol (all P<0.0001). Participants with a FLI≥60 showed higher prevalence of type 2 diabetes mellitus (9.3% vs. 1.4%), metabolic syndrome (54.2% vs. 6.2%), impaired renal function (20.1% vs. 8.7%) and cardiovascular disease (4.6% vs. 1.6%) (all P<0.0001). Multivariable logistic analysis showed that smoking, hemoglobin, leucocytes, c-reactive protein, platelets, alanine aminotransferase, alkaline phosphatase, albumin, impaired renal function (OR 1.27, 95%CI 1.15–1.41), metabolic syndrome (OR 11.89, 95%CI 11.03–12.82) and its individual components hyperglycemia (OR 2.53, 95%CI 2.34–2.72), hypertension (OR 1.89, 95%CI 1.77–2.01) and reduced high-density lipoprotein cholesterol (OR 3.44, 95%CI 3.22–3.68) were independently associated with suspected non-alcoholic fatty

  17. Real-time control of the period of individual ELMs by EC power on TCV

    NASA Astrophysics Data System (ADS)

    Felici, F.; Rossel, J. X.; Duval, B. P.; Coda, S.; Goodman, T. P.; Martin, Y.; Moret, J.-M.; Sauter, O.; the TCV Team

    2013-11-01

    The period of individual type-I edge-localized modes (ELMs) in TCV H-mode plasmas is controlled by real-time controlled application of electron cyclotron (EC) power close to the plasma pedestal. An ELM pacing algorithm, closely related to sawtooth pacing (Goodman et al (2011 Phys. Rev. Lett. 106 245002)) has been implemented in the TCV control system. This algorithm switches the EC power to a low level after detecting an ELM, and subsequently increases the power to a higher level after a pre-set time interval, stimulating the advent of the next ELM. While the mean ELM period is observed to depend only on the mean power applied, ELM pacing is shown to significantly regularize the ELM period with respect to the case of continuously applied power. It is also shown that the ELM period can be changed from one ELM to the next on time scales shorter than the global energy confinement time. These results present a challenging benchmark to physics-based pedestal models and can point towards obtaining a deeper understanding of the physics of individual ELM cycles.

  18. Characterization of density fluctuations during ELMs in the DIII-D tokamak

    NASA Astrophysics Data System (ADS)

    Coda, S.; Porkolab, M.; Burrell, K. H.

    2001-12-01

    Bursts of turbulence associated with ELMs have been studied systematically in DIII-D with a multichannel phase contrast imaging (PCI) diagnostic, which is sensitive to the long poloidal wavelength components of the density fluctuations in the outer edge of the tokamak. A comparison of the temporal dynamics of the turbulence with the signature Dα signal from the divertor has revealed systematic differences between type I and type III ELMs: even though precursor fluctuations are sometimes seen before type I ELMs, the PCI signal level remains high until the peak in the Dα signal; by contrast, in type III ELMs the fluctuation burst precedes the Dα peak by 0.4-0.6 ms. Type I ELMs can generate `echoes', i.e. secondary bursts, in the scrape-off layer. Coherent modes are observed during type III ELMs only. The radial and temporal correlation structures and the spectral properties of the turbulence during the transient ELM phase have been reconstructed by averaging over multiple ELMs, in order to improve the statistical accuracy. ELM turbulence is found to share many properties with L mode turbulence, including the main qualitative features of radial wavenumber and frequency spectra and radial dispersion relations. However, features unique to ELM turbulence are also identified.

  19. Mexican Hat Wavelet Kernel ELM for Multiclass Classification

    PubMed Central

    Wang, Jie; Ma, Tian-Lei

    2017-01-01

    Kernel extreme learning machine (KELM) is a novel feedforward neural network, which is widely used in classification problems. To some extent, it solves the existing problems of the invalid nodes and the large computational complexity in ELM. However, the traditional KELM classifier usually has a low test accuracy when it faces multiclass classification problems. In order to solve the above problem, a new classifier, Mexican Hat wavelet KELM classifier, is proposed in this paper. The proposed classifier successfully improves the training accuracy and reduces the training time in the multiclass classification problems. Moreover, the validity of the Mexican Hat wavelet as a kernel function of ELM is rigorously proved. Experimental results on different data sets show that the performance of the proposed classifier is significantly superior to the compared classifiers. PMID:28321249

  20. Imaging divertor strike point splitting in RMP ELM suppression experiments

    NASA Astrophysics Data System (ADS)

    Moyer, R. A.; Bykov, I.; Orlov, D. M.; Lee, J. S.; Evans, T. E.; Nazikian, R.; Makowski, M.; Lasnier, C. S.; Wang, H.; Abrams, T.; Watkins, J. G.

    2016-10-01

    Fast visible imaging of the lower divertor has been implemented at DIII-D to study the structure and dynamics of lobes induced by 3D fields in RMP ELM suppression experiments. The sharpest imaging was obtained with spatially localized molecular D2 emission indicative of the D flux to the surface. Multiple D2 emission peaks are readily resolved during RMPs, in contrast to the heat flux profile (from IR), which often shows little structure. The brightest D2 lobe is often farthest from the primary inner strike point (ISP). Mitigated ELMs perturb the position and intensity of the ISP lobes and spread the outer strike point emission into the far SOL, where it may be caused by ELM filament propagation. RMP current ramps affect the lobe locations and separations. Implications of the lobe dynamics for plasma response is being studied. Work supported by U.S. DOE under Grants DE-FG02-07ER54917 and DE-FG02-05ER54809, and Contracts DE-FC02-04ER54698, DE-AC52-07NA27344, DE-AC04-94AL85000, DE-AC05-06OR23100 and DE-AC02-09CH11466.

  1. Preliminary Process Design of ITER ELM Coil Bracket Brazing

    NASA Astrophysics Data System (ADS)

    LI, Xiangbin; SHI, Yi

    2015-03-01

    With the technical requirement of the International Thermonuclear Experimental Reactor (ITER) project, the manufacture and assembly technology of the mid Edge Localized Modes (ELM) coil was developed by the Institute of Plasma Physics, Chinese Academy of Science (ASIPP). As the gap between the bracket and the Stainless Steel jacketed and Mineral Insulated Conductor (SSMIC) can be larger than 0.5 mm instead of 0.01 mm to 0.1 mm as in normal industrial cases, the process of mid ELM coil bracket brazing to the SSMICT becomes quiet challenging, from a technical viewpoint. This paper described the preliminary design of ELM coil bracket brazing to the SSMIC process, the optimal bracket brazing curve and the thermal simulation of the bracket furnace brazing method developed by ANSYS. BAg-6 foil (Bag50Cu34Zn16) plus BAg-1a paste (Bag45CuZnCd) solders were chosen as the brazing filler. By testing an SSMICT prototype, it is shown that the average gap between the bracket and the SSMIC could be controlled to 0.2-0.3 mm, and that there were few voids in the brazing surface. The results also verified that the preliminary design had a favorable heat conducting performance in the bracket.

  2. Edge Stability in ELM-free QH and RMP Plasmas

    NASA Astrophysics Data System (ADS)

    Snyder, P. B.; Burrell, K. H.; Chu, M. S.; Osborne, T. H.; Wilson, H. R.; Konz, C.

    2006-10-01

    The peeling-ballooning model proposes that intermediate wavelength MHD instabilities cause edge localized modes (ELMs) and impose constraints on the pedestal height. In typical discharges, the pedestal goes unstable to coupled peeling-ballooning modes shortly before an ELM is observed. However, in ELM-free discharges, such as in the promising Quiescent (QH) and resonant magnetic perturbation (RMP) H-mode regimes, the edge collisionality is low, and the resulting large bootstrap current in the pedestal region drives kink/peeling modes (n˜,1-10). Both flows and the conducting wall have significant impact in this regime, and an edge localized resistive wall mode can be unstable. We present a theory for the occurrence of QH-mode, in which the observed edge harmonic oscillation (EHO) is a saturated low-n kink/peeling mode, which drives particle transport and allows a steady quiescent pedestal. In RMP discharges, we find that the imposed magnetic perturbation plays the role of the EHO, similarly allowing steady state quiescent discharges.

  3. Observations of ELM Magnetic Precursors and Harmonic Oscillations in NSTX

    NASA Astrophysics Data System (ADS)

    Kelly, F.; Frederickson, E.; Bell, R.; Tritz, K.; Takahashi, H.; Maingi, R.; NSTX Collaboration

    2011-10-01

    Recent experiments on NSTX have shown n=1 dominant and n=2 mode ELM magnetic precursors with mode frequency in the 30 to 90 kHz range. The growing magnetic oscillations measured with the NSTX high-n Mirnov diagnostic occurred simultaneous with the onset of the increase in fast D α signal. These bursts of dominantly n=1, some n=2 and fewer higher modes resemble the predictions of a model simulation of ELMs by T. Evans in which a feedback amplification mechanism causes explosive growth of the separatrix topology driven by thermoelectric currents in flux tubes connecting the divertor plates. The n=1 mode remained dominant as wall recycling was reduced with lithium conditioning and n=3 RMP was applied, suggesting the trigger mechanism remained the same. Sufficient lithium suppressed ELMs and made the occurrence of low-frequency, low-n Harmonics Oscillations (HOs) more frequent. The HOs are consistent with modes localized in the edge with the frequency of the n = 1 harmonic near the rotation frequency of the edge plasma. Work supported in part by US DOE contract no. DE-AC02-09CH11466.

  4. NSTX ELM Pacing and L-H Threshold Experiments for ITER

    NASA Astrophysics Data System (ADS)

    Canik, J. M.; Maingi, R.; Sontag, A. C.; Gerhardt, S. P.; Kaye, S.; Bell, R. E.; Gates, D.; Goldston, R.; Leblanc, B. P.; Menard, J.; Park, J.-K.; Evans, T.; Osborne, T.; Sabbagh, S.; Unterberg, E. A.

    2009-11-01

    We present a summary of recent edge-localized mode (ELM) pacing and L-H power threshold (PLH) experiments performed in NSTX in support of ITER. ELM triggering using 3D magnetic perturbations was used to perform pacing during ELM-free H-modes induced by lithium conditioning, mitigating the impurity accumulation typically observed in these conditions. The waveform of the applied field has been tailored to provide high reliability triggering at frequencies of >60 Hz to reduce the average ELM size. ELM pacing was also performed using vertical position oscillations, with the ELM frequency increased to ˜30 Hz from a natural frequency of ˜15 Hz. PLH is reduced by ˜50% at low triangularity, and also decreased by ˜50% during discharge with thick lithium wall coatings. PLH was observed to increase strongly with plasma current during sustained H-modes. The influence of heating method, non-axisymmetric fields, and magnetic balance on PLH will be presented.

  5. QUANTITATIVE TESTS OF ELMS AS INTERMEDIATE N PEELING-BALOONING MODES

    SciTech Connect

    LAO,LL; SNYDER,PB; LEONARD,AW; OIKAWA,T; OSBORNE,TH; PETRIE,TW; FERRON,JR; GROEBNER,RJ; HORTON,LD; KAMADA,Y; MURAKAMI,M; SAARELMA,S; STJOHN,HE; TURNBULL,AD; WILSON,HR

    2003-03-01

    A271 QUANTITATIVE TESTS OF ELMS AS INTERMEDIATE N PEELING-BALOONING MODES. Several testable features of the working model of edge localized modes (ELMs) as intermediate toroidal mode number peeling-ballooning modes are evaluated quantitatively using DIII-D and JT-60U experimental data and the ELITE MHD stability code. These include the hypothesis that ELM sizes are related to the radial widths of the unstable MHD modes, the unstable modes have a strong ballooning character localized in the outboard bad curvature region, and ELM size generally becomes smaller at high edge collisionality. ELMs are triggered when the growth rates of the unstable MHD modes become significantly large. These testable features are consistent with many ELM observations in DIII-D and JT-60U discharges.

  6. PROGRESS IN THE PEELING-BALLOONING MODEL OF ELMS: NUMERICAL STUDIES OF 3D NONLINEAR ELM DYNAMICS

    SciTech Connect

    SNYDER,P.B; WILSON,H.R; XU,X.Q

    2004-11-01

    Nonlinear simulations with the 3D electromagnetic two-fluid BOUT code are employed to study the dynamics of edge localized modes (ELMs) driven by intermediate wavelength peeling-ballooning modes. It is found that the early behavior of the modes is similar to expectations from linear, ideal peeling-ballooning mode theory, with the modes growing linearly at a fraction of the Alfven frequency. In the nonlinear phase, the modes grow explosively, forming a number of extended filaments which propagate rapidly from the outer closed flux region into the open flux region toward the outboard wall. Similarities to non-linear ballooning theory, as well as additional complexities are observed. Comparison to observations reveals a number of similarities. Implications of the simulations and proposals for the dynamics of the full ELM crash are discussed.

  7. The position of the Dutch Farmers' Union on lessons learned and future prevention and control of foot and mouth disease.

    PubMed

    Cuijpers, M P; Osinga, K J

    2002-12-01

    Foot and mouth disease (FMD) has devastated animal husbandry in The Netherlands frequently in the past and still constitutes a threat. The use of vaccination reduced the number of outbreaks in The Netherlands in the 20th Century. However, the desire of some member states of the European Community not to use vaccination led to a new strategy based on stamping-out of infected and contagious farms and to strict transportation regulations. In 2001, this proved very disruptive to the wider rural economy, such as the recreational and tourism sectors. The policy also caused severe animal welfare problems and psychological problems among farmers and their families. This raised questions about the wider, and not only veterinary or agricultural, implications of control strategies of foot and mouth disease virus (FMDV). The technology seems to be in place for a return to the use of protective vaccination against FMDV during an outbreak, provided the Office International des Epizooties (OIE: World organisation for animal health) and European Commission (EC) receive data that substantiate the reliability of differentiating tests such as the 3ABC enzyme-linked immunosorbent assay (ELISA) for use in individual animals. Research is in progress but may not be able to produce these data until 2003 or 2004. High potency vaccines should be used to elicit sufficient immunity within three to four days. During an FMD crisis, farmers should be assisted to find markets for products from areas affected by FMDV. The human dimension of any FMD outbreak must be dealt with sufficiently in any contingency plan.

  8. Fast dynamics of type I and grassy ELMs in JT-60U

    NASA Astrophysics Data System (ADS)

    Kojima, A.; Oyama, N.; Sakamoto, Y.; Kamada, Y.; Urano, H.; Kamiya, K.; Fujita, T.; Kubo, H.; Aiba, N.; JT-60 Team

    2009-11-01

    In order to understand the physics of the ELM trigger and determine the ELM size, the fast ELM dynamics of type I and grassy ELMs have been studied in JT-60U, using new fast diagnostics with high spatial and temporal resolutions such as a lithium beam probe (Δt ~ 0.5 ms) and a charge exchange recombination spectroscopy (Δt ~ 2.5 ms), which can measure the electron density and the ion temperature, respectively. The evolution of the ion pressure profile in the pedestal region has been evaluated for the first time by detailed edge profile measurements. Then, the dynamics of the density, the ion temperature and the ion pressure in the ELM cycle has been investigated. The co-rotating plasmas are compared with the counter (ctr)-rotating plasmas for the understanding of the toroidal rotation effects. Type I ELMs observed in co-rotating plasmas exhibit a larger and wider ELM affected area (Δnped/nped ~ 30%, radial extent >15 cm) than ctr-rotating plasmas (Δnped/nped ~ 20%, radial extent ~10 cm). Just before a type I ELM crash, the pedestal ion pressure and its maximum gradient in co-rotating plasmas are 20% and 12% higher than those in ctr-rotating plasmas, respectively. It is found that the radial extent of the ion pressure gradient at the pedestal region in co-rotating plasmas is 14% wider than that in ctr-rotating plasmas. The experimental results suggest that the ELM size is connected with the structure of the plasma pressure in the whole pedestal region. As for the dynamics of grassy ELMs, the collapse of density pedestal is smaller (<20%) and narrower (~5 cm) than those of type I ELMs, as observed in the collapse of the electron temperature pedestal. Thus, it is confirmed that both conductive and convective losses due to grassy ELMs are small.

  9. VizieR Online Data Catalog: The ELM survey. VII. 15 new ELM white dwarf cand. (Brown+, 2016)

    NASA Astrophysics Data System (ADS)

    Brown, W. R.; Gianninas, A.; Kilic, M.; Kenyon, S. J.; Allende Prieto, C.

    2016-05-01

    We present observations of 15 new extremely low-mass white dwarf (ELM WD) candidates. Ten objects are selected by color for our targeted spectroscopic ELM Survey program as described in Brown et al. (2012ApJ...744..142B). Five objects come from follow-up spectroscopy of the completed Hypervelocity Star survey. We acquire spectra for the 15 ELM WD candidates using the Blue Channel spectrograph on the 6.5m MMT telescope. We configured the Blue Channel spectrograph to obtain 3650-4500Å spectral coverage with 1.0Å spectral resolution. We acquire additional spectra for 5 objects using the KOSMOS spectrograph on the Kitt Peak National Observatory 4m Mayall telescope on program numbers 2014B-0119 and 2015A-0082. We configured the KOSMOS spectrograph to obtain 3500-6200Å spectral coverage with 2.0Å spectral resolution. We also acquire spectra for objects with g<17mag using the FAST spectrograph on the Fred Lawrence Whipple Observatory 1.5m Tillinghast telescope. We configured the FAST spectrograph to obtain 3500-5500Å spectral coverage with 1.7Å spectral resolution. (3 data files).

  10. Identification of characteristic ELM evolution patterns with Alfven-scale measurements and unsupervised machine learning analysis

    NASA Astrophysics Data System (ADS)

    Smith, David R.; Fonck, R. J.; McKee, G. R.; Diallo, A.; Kaye, S. M.; Leblanc, B. P.; Sabbagh, S. A.

    2016-10-01

    Edge localized mode (ELM) saturation mechanisms, filament dynamics, and multi-mode interactions require nonlinear models, and validation of nonlinear ELM models requires fast, localized measurements on Alfven timescales. Recently, we investigated characteristic ELM evolution patterns with Alfven-scale measurements from the NSTX/NSTX-U beam emission spectroscopy (BES) system. We applied clustering algorithms from the machine learning domain to ELM time-series data. The algorithms identified two or three groups of ELM events with distinct evolution patterns. In addition, we found that the identified ELM groups correspond to distinct parameter regimes for plasma current, shape, magnetic balance, and density pedestal profile. The observed characteristic evolution patterns and corresponding parameter regimes suggest genuine variation in the underlying physical mechanisms that influence the evolution of ELM events and motivate nonlinear MHD simulations. Here, we review the previous results for characteristic ELM evolution patterns and parameter regimes, and we report on a new effort to explore the identified ELM groups with 2D BES measurements and nonlinear MHD simulations. Supported by U.S. Department of Energy Award Numbers DE-SC0001288 and DE-AC02-09CH11466.

  11. Important role of pedestal ion temperature in the ELM mitigation by supersonic molecular beam injection

    NASA Astrophysics Data System (ADS)

    Ma, Q.; Yu, D. L.; Chen, C. Y.; Wei, Y. L.; Zhong, W. L.; Zou, X. L.; Zuo, H. Y.; Du, J. L.; Liu, L.; Dong, C. F.; Shi, Z. B.; Zhao, K. J.; Feng, B. B.; Zhou, Y.; Wang, Z. H.; Xu, M.; Liu, Yi; Yan, L. W.; Yang, Q. W.; Yao, L. H.; Ding, X. T.; Dong, J. Q.; Duan, X. R.; Liu, Yong; HL-2A Team

    2016-12-01

    Edge localized mode (ELM) is successfully mitigated by helium and deuterium supersonic molecular beam injections (SMBIs) on HL-2A. During the ELM mitigation by SMBIs, gradients of ion temperature (T i) and electron density are softened in the pedestal. It has been observed that the averaged gradient of the T i decreases around 44% and the well depth of radial electric field (E r) is reduced by the SMBI during ELM mitigation. Furthermore, at least 20% decrements of T i have to be attained to achieve a noticeable increase (decrease) of the ELM frequency (amplitude). In addition, the duration of ELM mitigation with helium SMBI is much longer than that with deuterium, likely due to the higher level of recycling neutral gas compared to that of deuterium; in the case of ELM mitigation by helium SMBI, the recovery duration of the density gradient is much shorter (10-20 ms) than that of T i (up to 40 ms or longer), indicating the importance of the T i in the ELM mitigation by SMBI. Finally, it has been observed that the T i is reduced before the beginning of the ELM mitigation, suggesting that the mechanism of the ELM mitigation by SMBI is closely related to the cooling effect.

  12. Nonlinear interaction between edge-localized modes (ELMs) and edge turbulence during ELM-crash-suppression phase under n=1 RMP

    NASA Astrophysics Data System (ADS)

    Lee, Jaehyun; Yun, Gunsu; Choi, Minjun; Kwon, Jae-Min; Jeon, Young-Mu; Lee, Woochang; Luhmann, Neville C., Jr.; Park, Hyeon K.

    2016-10-01

    Mutual interactions between edge-localized modes (ELMs) and turbulent eddies have been investigated in 2-D by using the KSTAR electron cyclotron emission imaging (ECEI) system. ECEI shows that ELM filaments still exist in the edge when the usual large scale collapse of the edge pedestal, i.e., the ELM crash, is completely suppressed by n = 1 resonant magnetic perturbation (RMP). Correlation analysis among ECEI channels reveals that the RMP enhances turbulent fluctuations in the edge and that ELM crashes are suppressed when the RMP exceeds a certain threshold. The spectral power distribution of turbulence shows a clear dispersion for a wide range of wavenumber (kθ < 1 cm-1) and frequency (f < 70 kHz). The radial velocity and ECE intensity fluctuations of the turbulent eddies are approximately in-phase and thus the turbulence involves a net radial energy transport. Bispectral analysis indicates the coexisting ELMs and turbulent eddies nonlinearly interact with each other. Both the enhancement of radial transport and the nonlinear interaction with ELMs may be the key to the physics mechanism of ELM-crash-suppression by low-n RMP. This work was supported by National Research Foundation of Korea under Grant No. NRF-2014M1A7A1A03029865 and NRF-2014M1A7AA03029881.

  13. Impact of a pulsed supersonic deuterium gas jet on the ELM behaviour in ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Lang, P. T.; Neuhauser, J.; Bucalossi, J.; Chankin, A.; Coster, D. P.; Drube, R.; Dux, R.; Haas, G.; Horton, L. D.; Kalvin, S.; Kocsis, G.; Maraschek, M.; Mertens, V.; Rohde, V.; Rozhansky, V.; Schneider, R.; Senichenkov, I.; Veselova, I.; Wolfrum, E.; ASDEX Upgrade Team

    2005-09-01

    The possibility for pacing of type-I edge localized modes (ELMs) in H-mode plasmas by intermittent gas injection was investigated in ASDEX Upgrade as a possible alternative to, and in comparison with, ELM control by pellets. A Laval nozzle type molecular deuterium injector was used, delivering 1.7 ms long jets with up to about 1020D per pulse at a supersonic flow velocity of 2.2 km s-1. With a repetition rate of 2 Hz and a fast rise time of ap25 µs, comparable to typical ELM rise times, the injector seemed to be well-suited for single ELM trigger tests. When applied to H-mode discharges with a moderate type-I ELM frequency of 40-60 Hz, no prompt (<0.5 ms) ELM triggering could be achieved, in contrast to the experience with pellets. There was, however, clear evidence for a delayed effect in the form of an inverse correlation of the gas pulse amplitude with the time interval between the gas pulse and the next ELM. The apparent lack of prompt ELM triggering seems to be due to a self-blocking of the gas jet by an extremely fast formation of a high density plasma layer in the separatrix vicinity, while the delayed effect may be simply caused by the jet-induced axisymmetric edge profile modification, similar to the delayed ELM cascade observed after a prompt ELM in case of large pellet injection. The delayed trigger effect observed might still be useful for ELM control in future machines, but the related high gas fuelling at elevated pulse frequency could make it unattractive in view of overall plasma performance.

  14. Latest investigations on fluctuations, ELM filaments and turbulent transport in the SOL of ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Müller, H. W.; Adamek, J.; Cavazzana, R.; Conway, G. D.; Fuchs, C.; Gunn, J. P.; Herrmann, A.; Horaček, J.; Ionita, C.; Kallenbach, A.; Kočan, M.; Maraschek, M.; Maszl, C.; Mehlmann, F.; Nold, B.; Peterka, M.; Rohde, V.; Schweinzer, J.; Schrittwieser, R.; Vianello, N.; Wolfrum, E.; Zuin, M.; ASDEX Upgrade Team

    2011-07-01

    This paper presents turbulence investigations in the scrape-off layer (SOL) of ASDEX Upgrade in ohmic, L-mode and H-mode discharges using electrostatic and electromagnetic probes. Detailed studies are performed on small scale turbulence and on ELM filaments. Simultaneous measurements of floating and plasma potential fluctuations revealed significant differences between these quantities. Large errors can occur when the electric field is extracted from floating potential measurements, even in ohmic discharges. Turbulence studies in ohmic plasmas show the existence of density holes inside the separatrix and blobs outside. Close to the separatrix a reversal of the poloidal blob propagation velocity occurs. Investigations on the Reynolds stress in the scrape-off layer (SOL) show its importance for the momentum transport in L-mode while its impact for momentum transport during ELMs in H-mode is rather small. In the far SOL the electron density and temperature were measured during type-I ELMy H-mode at ASDEX Upgrade resolving ELM filaments. Strong density peaks and temperatures of several 10 eV were detected during the ELM events. Additional investigations on the ions in ELM filaments by a retarding field analyser indicate ion temperatures of 50-80 eV. ELMs also expel current concentrated in filaments into the SOL. Furthermore, discharges with small ELMs were studied. In N2 seeded discharges the type-I ELM frequency rises and the ELM duration decreases. For discharges with small type-II ELMs the mean turbulent radial particle flux is increased over the mean particle flux in type-I ELM discharges at otherwise similar plasma parameters.

  15. Observations of the effect of lower hybrid waves on ELM behaviour in EAST

    NASA Astrophysics Data System (ADS)

    Chen, R.; Xu, G. S.; Liang, Y.; Wang, H. Q.; Zhou, C.; Liu, A. D.; Wang, L.; Qian, J. P.; Gan, K. F.; Yang, J. H.; Duan, Y. M.; Li, Y. L.; Ding, S. Y.; Wu, X. Q.; Yan, N.; Chen, L.; Shao, L. M.; Zhang, W.; Hu, G. H.; Zhao, N.; Liu, S. C.; Kong, D. F.; Gong, X. Z.

    2015-03-01

    Dedicated experiments focusing on the influence of lower hybrid waves (LHWs) on edge-localized modes (ELMs) were first performed during the 2012 experimental campaign of EAST, via modulating the input power of LHWs in the high-confinement-mode (H-mode) plasma mainly sustained by ion cyclotron resonant heating. Natural ELMs are effectively mitigated (ELM frequency increases, while its intensity decreases dramatically) as the LHW is applied, observed over a fairly wide range of plasma current or edge safety factor. By scanning the modulation frequency (fm) of LHW injected power in a target plasma dominated by the so-called small ELMs, we conclude that large ELMs with markedly larger amplitudes and lower frequencies are reproduced at low modulation frequencies (fm < 100 Hz). Analysis of the evolution of edge extreme ultraviolet radiation signals further indicates that plasma fluctuations at the pedestal region indistinctively respond to rapid modulation (fm ⩾ 100 Hz) of LHW injected power. This is proposed as the mechanism responsible for the observed fm dependence of the mitigation effect induced by LHWs on large ELMs. In addition, a critical threshold of LHW input power PLHW is estimated as PLHWthr≃800 kW , beyond which the impact of applied LHWs on ELM behaviours can be achieved. Finally, Langmuir probe measurements suggest that, rather than the concentration of free energy into a narrowband quasi-coherent precursor commonly observed growing until the ELM crash, the continuous development of broadband turbulence during the ELM-absent phase with the application of LHWs might contribute to the avoidance of ELM crashes. These results present new insights into existing experiments, and also provide some foundations and references for the next-step research about exploring in more depth and improving this new attractive method to effectively control the ELM-induced very large transient heat and particle flux.

  16. A New Dutch Spelling Guide.

    ERIC Educational Resources Information Center

    Kruyt, J. G.; van Sterkenburg, P. G. J.

    This paper describes the development of two new corpus-based Dutch spelling guides using language data gathered by the Institute for Dutch Lexicology, a research institute subsidized by the Dutch and Belgian governments. The guides were produced in 1990 and 1995. The guides are based on two earlier ones, published in 1866 and 1954, but attempt to…

  17. Pacing control of sawtooth and ELM oscillations in tokamaks

    NASA Astrophysics Data System (ADS)

    Lauret, M.; Lennholm, M.; de Baar, M. R.; Heemels, W. P. M. H.

    2016-12-01

    In tokamak plasmas, the sawtooth oscillation (ST) and the edge-localized-mode (ELM) are characterized by a phase of a slow evolution of the plasma conditions, followed by a crash-like instability that resets the plasma conditions when certain criteria of the plasma conditions are satisfied. Typically, the crashes induce losses of heat and energetic particles and may also trigger secondary instabilities. As the amplitude of the crash-like perturbation scales with the period between two crashes, period control of these oscillations is important for operations of large fusion facilities such as ITER and DEMO. In several present-day experimental facilities, a pacing control algorithm has been successfully applied for controlling the sawtooth period and the ELM period. However, a formal analysis has been lacking so far, which therefore forms the objective of the present paper. For this purpose, a reset model for the sawtooth period is introduced and, after a proper transformation a nonlinear discrete-time system is obtained, which is used for the formal analysis of pacing control. By representing the model in a Lur’e (or Lurie) form, we can derive conditions under which global asymptotic stability of the closed-loop (pacing) period control system is guaranteed. Moreover, we will show that the controller exhibits inherent robustness for model uncertainties. We envision that the analytical results in the area of pacing control of the sawtooth are also applicable to pacing period control of the ELM oscillation period. The presented reset model also explains why in recent experiments the sawtooth period locks with a periodically modulated power.

  18. ELM Meets Urban Big Data Analysis: Case Studies

    PubMed Central

    Chen, Huajun; Chen, Jiaoyan

    2016-01-01

    In the latest years, the rapid progress of urban computing has engendered big issues, which creates both opportunities and challenges. The heterogeneous and big volume of data and the big difference between physical and virtual worlds have resulted in lots of problems in quickly solving practical problems in urban computing. In this paper, we propose a general application framework of ELM for urban computing. We present several real case studies of the framework like smog-related health hazard prediction and optimal retain store placement. Experiments involving urban data in China show the efficiency, accuracy, and flexibility of our proposed framework. PMID:27656203

  19. Impurity radiation and the theory of ELMs in a tokamak

    SciTech Connect

    Morozov, D.K.; Roitman, A.V.

    1994-11-01

    A modification of the theory proposed by Kukharkin, Osipenko, and Pogutse is presented. An account of impurity radiation allows the authors to explain the absence of ELMs in the VH-mode of operation, and their arising during the transition to the ordinary H-mode. It is demonstrated that the radiation, whose intensity and temperature dependence are functions of the base gas neutral atom concentration, plays an essential destabilizing role. In the VH-mode, when the neutral atom concentration is low, the flute mechanism of the instability is suppressed, the radiation does not play a substantial role, and the mode is stable. 4 refs., 2 figs.

  20. ELM Suppression and Pedestal Structure in I-Mode Plasmas

    NASA Astrophysics Data System (ADS)

    Walk, John

    2013-10-01

    The I-mode regime is characterized by the formation of a temperature pedestal and enhanced energy confinement (H98 up to 1.2), without an accompanying density pedestal or drop in particle transport. Unlike ELMy H-modes, I-mode operation appears to have naturally-occurring suppression of large ELMs in addition to its highly favorable scalings of pedestal structure (and therefore overall performance). Instead, continuous Weakly Coherent Modes help to regulate density. Extensive study of the ELMy H-mode has led to the development of the EPED model, which utilizes calculations of coupled peeling-ballooning MHD modes and kinetic-ballooning mode (KBM) stability limits to predict the pedestal structure preceding an ELM crash. We apply similar tools to the structure and ELM stability of I-mode pedestals. Peeling-ballooning MHD calculations are completed using the ELITE code, showing I-mode pedestals to be generally MHD-stable. Under certain conditions, intermittent ELMs are observed in I-mode at reduced field, typically triggered by sawtooth crashes; modification of the temperature pedestal (and therefore the pressure profile stability) by sawtooth heat pulses is being examined in ELITE. Modeled stability to KBM turbulence in I-mode and ELMy H-mode suggests that typical I-modes are stable against KBM turbulence. Measured I-mode pedestals are significantly wider (more stable) than the width scaling with the square root of poloidal beta characteristic of the KBM-limited pedestals in ELMy H-mode. Finally, we explore scalings of pedestal structure with engineering parameters compared to ELMy H-modes on C-Mod. In particular, we focus on scalings of the pressure pedestal with heating power (and its relation to the favorable scaling of confinement with power in I-mode) and on relationships between heat flux and pedestal temperature gradients. This work is supported by DOE agreement DE-FC02-99ER54512. Theory work at General Atomics is supported by DOE agreement DE-FG02-99ER54309.

  1. ELM-ART--An Interactive and Intelligent Web-Based Electronic Textbook

    ERIC Educational Resources Information Center

    Weber, Gerhard; Brusilovsky, Peter

    2016-01-01

    This paper present provides a broader view on ELM-ART, one of the first Web-based Intelligent Educational systems that offered a creative combination of two different paradigms--Intelligent Tutoring and Adaptive Hypermedia technologies. The unique dual nature of ELM-ART contributed to its long life and research impact and was a result of…

  2. Toroidal mode number determination of ELM associated phenomena on ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Mink, Felician; Wolfrum, Elisabeth; Maraschek, Marc; Zohm, Hartmut; Horváth, László; Laggner, Florian M.; Manz, Peter; Viezzer, Eleonora; Stroth, Ulrich; the ASDEX Upgrade Team

    2016-12-01

    In highly confined tokamak plasmas periodically appearing edge localized modes (ELMs) are accompanied by mode-like magnetohydrodynamic (MHD) activities with defined toroidal mode numbers. Here the method of determining toroidal mode numbers n on the ASDEX Upgrade tokamak with a toroidally spread magnetic pick-up coil array is reviewed and improved by taking into account intrinsic coil phases. ELM synchronization is used to characterize inter-ELM MHD activity and their development during the ELM cycle in terms of their mode numbers. The mode number development is correlated with the development of the pedestal parameters which shows that the inter-ELM modes cause transport across the pedestal. An estimation of the position of the modes is done via a comparison between the mode velocities and the plasma rotation profile at the edge. Results show that during the ELM cycle MHD modes appear at several positions in the strong gradient region with clearly defined toroidal structures in the range of n  =  1-10. These structures of inter-ELM modes are preserved during the ELM crash where also a strong n  =  0 phenomenon occurs.

  3. Comparison of Small ELM Characteristics and Regimes in Alcator C-Mod, MAST, and NSTX

    SciTech Connect

    Maingi, Rajesh; Hubbard, A.E.; Meyer, H.; Kirk, A.; Maqueda, R.; Terry, J. L.

    2011-01-01

    We report on the status of a set of ITPA-coordinated experiments between the Alcator C-Mod, MAST and NSTX devices to compare the characteristics and access conditions of discharges with small edge-localized modes (ELMs). The small ELMs in C-Mod, MAST and one of the two small ELM types in NSTX exist when {beta}{sub ped}{sup pol} approached 10-15%, although the lower/upper limits of the operational windows differ. These small ELM regimes appear in diverted configurations very close to balanced double-null in each device. We classify these small ELMs as type II, based on the published characteristics from a number of previous studies. In addition, these type II ELMs in each device had multiple filaments with propagation in the co-I{sub p} or ion diamagnetic drift direction. Moreover, we conclude that these type II ELMs are distinct from the type V ELMs routinely observed in NSTX, which have one or two filaments and propagate in the electron diamagnetic drift direction.

  4. Co-occurence of Two Invasive Species: The Banded and European Elm Bark Beetles (Coleoptera: Scolytidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The invasive European elm bark beetle, Scolytus multistriatus (Marsham), was first detected a century ago and now occurs in most of the continental United States. The invasive banded elm bark beetle, Scolytus schevyrewi Semenov, native to Asia, was discovered in the United States in 2003 and is now...

  5. Impact of ELM filaments on divertor heat flux dynamics in NSTX

    SciTech Connect

    Ahn, J. -W.; Maingi, Rajesh; Canik, John M.; Gan, K. F.; Gray, Travis K.; McLean, A. G.

    2015-01-01

    In this study, the ELM induced change in wetted area (Awet) and peak heat flux (qpeak) of divertor heat flux is investigated as a function of the number of striations, which represent ELM filaments, observed in the heat flux profile in NSTX. More striations are found to lead to larger Awet and lower qpeak. The typical number of striations observed in NSTX is 0–9, while 10–15 striations are normally observed in other machines such as JET, and the ELM contracts heat flux profile when the number of striations is less than 3–4 but broadens it with more of them. The smaller number of striations in NSTX is attributed to the fact that NSTX ELMs are against kink/peeling boundary with lower toroidal mode number (n = 1–5), while typical peeling–ballooning ELMs have higher mode number of n = 10–20. For ELMs with smaller number of striations, relative Awet change is rather constant and qpeak change rapidly increases with increasing ELM size, while Awet change slightly increases leading to a weaker increase of qpeak change for ELMs with larger number of striations, both of which are unfavourable trend for the material integrity of divertor tiles.

  6. THE ELM SURVEY. III. A SUCCESSFUL TARGETED SURVEY FOR EXTREMELY LOW MASS WHITE DWARFS

    SciTech Connect

    Brown, Warren R.; Kenyon, Scott J.; Kilic, Mukremin; Allende Prieto, Carlos E-mail: skenyon@cfa.harvard.edu E-mail: callende@iac.es

    2012-01-10

    Extremely low mass (ELM) white dwarfs (WDs) with masses < 0.25 M{sub Sun} are rare objects that result from compact binary evolution. Here, we present a targeted spectroscopic survey of ELM WD candidates selected by color. The survey is 71% complete and has uncovered 18 new ELM WDs. Of the seven ELM WDs with follow-up observations, six are short-period binaries and four have merger times less than 5 Gyr. The most intriguing object, J1741+6526, likely has either a pulsar companion or a massive WD companion making the system a possible supernova Type Ia or an Ia progenitor. The overall ELM survey has now identified 19 double degenerate binaries with <10 Gyr merger times. The significant absence of short orbital period ELM WDs at cool temperatures suggests that common envelope evolution creates ELM WDs directly in short period systems. At least one-third of the merging systems are halo objects, thus ELM WD binaries continue to form and merge in both the disk and the halo.

  7. The Relationships Between ELM Suppression, Pedestal Profiles, and Lithium Wall Coatings in NSTX

    SciTech Connect

    D.P. Boyle, R. Maingi, P.B. Snyder, J. Manickam, T.H. Osborne, R.E. Bell, B.P. LeBlanc, and the NSTX Team

    2012-08-17

    Recently in the National Spherical Torus Experiment (NSTX), increasing lithium wall coatings suppressed edge localized modes (ELMs), gradually but not quite monotonically. This work details profile and stability analysis as ELMs disappeared throughout the lithium scan. While the quantity of lithium deposited between discharges did not uniquely determine the presence of ELMs, profile analysis demonstrated that lithium was correlated to wider density and pressure pedestals with peak gradients farther from the separatrix. Moreover, the ELMy and ELM-free discharges were cleanly separated by their density and pedestal widths and peak gradient locations. Ultimately, ELMs were only suppressed when lithium caused the density pedestal to widen and shift inward. These changes in the density gradient were directly reflected in the pressure gradient and calculated bootstrap current. This supports the theory that ELMs in NSTX are caused by peeling and/or ballooning modes, as kink/peeling modes are stabilized when the edge current and pressure gradient shift away from the separatrix. Edge stability analysis using ELITE corroborated this picture, as reconstructed equilibria from ELM-free discharges were generally farther from their kink/peeling stability boundaries than ELMy discharges. We conclude that density profile control provided by lithium is the key first step to ELM suppression in NSTX

  8. Theory and Modeling of ELMs and Constraints on the H-Mode Pedestal

    NASA Astrophysics Data System (ADS)

    Snyder, P. B.; Ferron, J. R.; Lao, L. L.; Leonard, A. W.; Osborne, T. H.; Turnbull, A. D.; Wilson, H. R.; Webster, A. J.; Xu, X. Q.; Mossessian, D.; Murakami, M.

    2002-11-01

    We present a theory of edge localized modes (ELMs) and constraints on the H-mode pedestal, based on the stability of intermediate wavelength peeling-ballooning modes driven by the strong pressure gradient and resulting bootstrap current in the pedestal region. Detailed studies of ideal MHD pedestal stability bounds are presented using the ELITE code, and are compared to data from multiple tokamaks. Observed ELM onset times and characteristics, as well as variation in pedestal behavior with discharge shape and collisionality, are studied. In addition, the impact of diamagnetic stabilization and rotation shear are assessed, and progress on dynamic modeling of the ELM cycle which couples transport codes to stability calculations and ELM crash models is briefly discussed. Nonlinear simulations using the BOUT code are used to provide further insight on non-ideal effects and ELM crash dynamics.

  9. Critical aspects of ELM crash suppression by magnetic perturbations in KSTAR

    NASA Astrophysics Data System (ADS)

    Kim, Jayhyun; Jeon, Y. M.; Park, G. Y.; Choi, M. J.; in, Y.; Yoon, S. W.; Bae, C.; Lee, J.; Park, J.-K.; Ahn, J.; The Kstar Team Team

    2016-10-01

    ELM crash suppressions have been achieved by low n (n = 1, 2, and mixture of them) magnetic perturbations (MPs) with using various configurations of in-vessel perturbation coils in KSTAR. So far, the suppressed periods are extended longer than 10 seconds. In KSTAR, the complete suppression of ELM crashes almost always accompany with the increase of edge fluctuations which are likely to be excited by applied MPs. The excitation of edge fluctuation exhibited the bifurcation-like feature depending on the strength of MPs. The conditions to excite edge fluctuations were investigated with including well known q95 window. On the other hand, ELM mitigation does not come with the increase of edge fluctuations. Instead, it seems that applied MPs directly trigger small frequent ELMs since the mitigated ELMs suddenly disappear when turning MPs off. The results stress the importance of stability analysis with the use of perturbed equilibrium since most stability studies have assumed unperturbed/undistorted equilibrium.

  10. Biology of the invasive banded elm bark beetle, Scolytus schevyrewi Semenov (Coleoptera: Scolytidae), in the western United States

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The invasive banded elm bark beetle, Scolytus schevyrewi Semenov, native to Asia, was detected in the United States in 2003 and is now known to occur in 28 states and four Canadian Provinces. S. schevyrewi infests the same elm hosts as the long-established invasive, and smaller European elm bark be...

  11. A Fully Noninductive, ELM-Suppressed Scenario for ITER

    NASA Astrophysics Data System (ADS)

    Petty, C. C.; Petrie, T. W.; Nazikian, R.; Turco, F.; Lasnier, C.

    2016-10-01

    An attractive regime with beta, collisionality and plasma shape relevant to the ITER steady-state mission has been attained in DIII-D using the hybrid scenario, including complete ELM suppression using resonant magnetic perturbation (RMP) coils. Fully noninductive hybrids with simultaneous high beta (βN <= 3.1) and high confinement (H98 y 2 <= 1.4) have achieved zero surface loop voltage for up to two current relaxation times using efficient central current drive from ECCD and NBCD. This steady-state regime has been successfully integrated with ELM suppression by applying an odd parity n=3 RMP, which has only a minor impact on the pedestal pressure ( 15 %) and H98 y 2 ( 10 %) In radiating divertor experiments in hybrids, the combination of Argon seeding and strong Deuterium puffing more than doubles the plasma radiative power, up to 55% of the input power, with less than 10% increase in Zeff. IR camera measurements find that the peak heat flux in the upper, outer divertor falls by a factor of 2 (from 4.6 to 2.3 MW /m2). Work supported by USDOE under DE-FC02-04ER54698, DE-AC02-09CH11466, DE-FG02-04ER54761, and DE-AC52-07NA27344.

  12. Modeling carbon production and transport during ELMs in DIII-D

    NASA Astrophysics Data System (ADS)

    Hogan, J.; Wade, M.; Coster, D.; Lasnier, C.

    2004-11-01

    Large-scale Type I ELM events could provide a significant C source in ITER, and C production rates depend on incident D flux density and surface temperature, quantities which can vary significantly during an ELM event. Recent progress on DIII-D has improved opportunities for code comparison. Fast time-scale measurements of divertor CIII evolution [1] and fast edge CER measurements of C profile evolution during low-density DIII-D LSN ELMy H-modes (type I) [2] have been modeled using the solps5.0/Eirene99 coupled edge code and time dependent thermal analysis codes. An ELM model based on characteristics of MHD peeling-ballooning modes reproduces the pedestal evolution. Qualitative agreement for the CIII evolution during an ELM event is found using the Roth et al annealing model for chemical sputtering and the sensitivity to other models is described. Significant ELM-to-ELM variations in observed maximum divertor target IR temperature during nominally identical ELMs are investigated with models for C emission from micron-scale dust particles. [1] M Groth, M Fenstermacher et al J Nucl Mater 2003, [2] M Wade, K Burrell et al PSI-16

  13. H-mode and ELM Characteristics at Ultralow Aspect Ratio in the Pegasus Experiment

    NASA Astrophysics Data System (ADS)

    Fonck, R. J.; Barr, J. L.; Bongard, M. W.; Kriete, D. M.; Perry, J. M.; Reusch, J. A.; Thome, K. E.

    2016-10-01

    Operation at low BT and A < 1.3 allows access to the H-mode regime in the Pegasus experiment using only Ohmic heating. Modest plasma parameters in this regime permit detailed probe measurements of the edge pedestal region. H-mode plasmas have standard L-H transition phenomena: a drop in Dα radiation; formation of pressure and current pedestals; field-aligned filament ejection during ELMs; and a doubling of τE from H98 0.5 to 1 . The L-H power threshold PLH increases monotonically with ne, consistent with both the ITPA08 scaling, PITPA 08 , used for ITER and the theoretical FM3 power threshold model. Unlike at high A, PLH is comparable in limited and single-null diverted topologies at A 1.2 , consistent with FM3 predictions. PLH /PITPA 08 increases rapidly as A -> 1 , and is > 10 for A < 1.3 . Multiple- n modes are observed during ELMs, consistent with excitation of multiple peeling-ballooning modes. Small, Type-III-like ELMs occur at POH PLH with n <= 4 . Large, Type-I-like ELMs occur with POH >PLH and intermediate 5 < n < 15 . High-resolution spatiotemporal measurements of Jedge(R , t) across single ELMs show the nonlinear generation and expulsion of current-carrying filaments during the large ELM crash. Helical edge current injection appears to suppress small ELM activity. Work supported by US DOE Grant DE-FG02-96ER54375.

  14. Study of ELM Density Turbulence using the Upgraded Phase Contrast Imaging on DIII-D

    NASA Astrophysics Data System (ADS)

    Rost, J. C.; Davis, E. M.; Marinoni, A.; Porkolab, M.; Burrell, K. H.

    2016-10-01

    Recent studies of the turbulent density fluctuations accompanying ELMs in mixed ELM-type discharges have exploited the expanded wavenumber range of the upgraded Phase Contrast Imaging (PCI) diagnostic. The PCI data demonstrate the difference between the fluctuations generated by Type I ELMs, which are broadband in frequency and wavelength, and those generated by Type III ELMs, which are similar in amplitude but restricted to long wavelengths, suggesting that turbulence may play a significant role in Type I ELM transport. The high frequency response of PCI makes it ideal for studying the ELM-associated density fluctuations, which are observed at frequencies up to several MHz, evolve on time scales of 10s of μs, and persist after the magnetic component of the ELM has decayed away. The upgraded PCI, with independent systems for long and short wavelength detection (k < 5 cm-1 and 1 < k < 30 cm-1 respectively), demonstrated coverage of the full wavenumber range of interest. Work supported in part by the US Department of Energy under DE-FG02-94ER54235, DE-FC02-04ER54698, and DE-FC02-99ER54512.

  15. Calibration of Model for Tokamak H-mode Pedestal and ELMs

    NASA Astrophysics Data System (ADS)

    MacDonald, C.; Bateman, G.; Kritz, A. H.; McElhenny, J.; Osborne, T.; Pankin, A. Y.

    2004-11-01

    Experimental data is used to calibrate a model for the pedestal and Edge Localized Modes (ELMs) implemented in the ASTRA integrated code. The model is calibrated to predict the frequency of the ELMs and the height of the electron and ion temperature pedestals just before an ELM crash. Detailed comparisons are made with experimental data from the DIII-D 98889 discharge, in which the noise in the data is reduced by overlaying the plasma profiles from a sequence of consecutive, nearly identical ELM cycles. The model includes neoclassical transport and transport driven by ion drift modes, resistive ballooning modes, and the electron gradient temperature mode. The criterion for triggering ELM crashes allows for access to second stability. The calibration is carried out by adjusting: (1) The flow shear rates for individual modes of long wavelength turbulent transport; (2) the stability criterion that is used to trigger ELM crashes; and (3) the shapes of the plasma profiles and plasma energy lost after each ELM crash. The calibration is presented as well as the sensitivity to the coefficients in the model.

  16. Non-linear MHD Simulation of ELMs including Pellet Triggered ones for KSTAR tokamak

    NASA Astrophysics Data System (ADS)

    Han, Hyunsun; Park, G.; Strauss, H.; Kim, J. Y.

    2011-10-01

    Three-dimensional non-linear MHD simulations have been conducted to investigate the qualitative characteristics of ELM(Edge Localized Mode)s including pellet induced ones using the M3D code. A linearized velocity perturbation of initial equilibrium is employed to trigger the ELM instability for the simulation of natural ELM, while a density blob, which represents the ionized pellet ablation and is located within the edge pedestal, is adopted in an adiabatic condition for that of pellet induced one. The initial equilibrium is constructed based on a H-mode plasma of KSTAR(Korea Superconducting Tokamak Advanced Research) device. It is found that characteristics of natural ELM simulation are in qualitative agreement with the experimental observations including that density perturbation is much larger than temperature one during ELM instability. Regarding the pellet induced ELM, it is observed that the locally increased pressure due to the fast parallel heat conduction compared to the spread of density perturbation triggers the peeling-ballooning instability resulting in ELM-like relaxation. Detailed results will be presented in the discussion of underlying mechanism and application to KSTAR tokamak.

  17. Advances in the physics understanding of ELM suppression using resonant magnetic perturbations in DIII-D

    SciTech Connect

    Wade, M. R.; Nazikian, R.; deGrassie, John S.; Evans, T. E.; Ferraro, N. M.; Moyer, R. A.; Orlov, D. M.; Buttery, R. J.; Fenstermacher, Max E.; Garofalo, Andrea M.; Lanctot, M. A.; McKee, George R.; Osborne, T. H.; Shafer, M. A.; Solomon, W. M.; Snyder, P. B.; Suttrop, Wolfgang; Wingen, Andreas; Unterberg, Ezekial A.; Zeng, L.

    2015-01-14

    Recent experiments on DIII-D have increased confidence in the ability to suppress edge-localized modes (ELMs) using edge-resonant magnetic perturbations (RMPs) in ITER, including an improved physics basis for the edge response to RMPs as well as expansion of RMP ELM suppression to more ITER-like conditions. In this study, complete ELM suppression has been achieved utilizing n = 3 RMPs in the ITER baseline scenario. In addition, RMP ELM suppression has been expanded to include plasmas with helium concentrations near 25% and the use of n = 2 RMPs. Analysis of the kinetic profile response suggests that ELM suppression is correlated with the co-alignment of the ω⊥e = 0 location, an n = 3 rational surface, and the top of the pedestal. Modelling predicts that such a co-alignment could potentially lead to island (or island chain) formation just inside the top of the pedestal, inhibiting the growth of the pedestal and thereby maintaining the ELM-free state. Detailed analysis of data obtained during toroidal phase variations of the applied n = 3 RMPs have provided further evidence of an island-like structure at the top of the pedestal. In addition, nearly matched discharges with co-neutral-beam-injection (co-NBI) and counter-NBI have demonstrated the importance of the presence of the ω⊥e = 0 location for ELM suppression. Finally, in the counter-NBI cases, the toroidal rotation profile is such that there is no ω⊥e = 0 location and ELMs are not suppressed in conditions in which ELM suppression is generally observed with co-NBI.

  18. Real-time control of ELM and sawtooth frequencies: similarities and differences

    NASA Astrophysics Data System (ADS)

    Lennholm, M.; Frigione, D.; Graves, J. P.; Beaumont, P. S.; Blackman, T.; Carvalho, I. S.; Chapman, I.; Dumont, R.; Felton, R.; Garzotti, L.; Goniche, M.; Goodyear, A.; Grist, D.; Jachmich, S.; Johnson, T.; Lang, P.; Lerche, E.; de la Luna, E.; Monakhov, I.; Mooney, R.; Morris, J.; Nave, M. F. F.; Reich, M.; Rimini, F.; Sips, G.; Sheikh, H.; Sozzi, C.; Tsalas, M.; Contributors, JET

    2016-01-01

    ELMs and Sawteeth, located in different parts of the plasma, are similar from a control engineering point of view. Both manifest themselves through quiescent periods interrupted by periodic collapses. For both, large collapses, following long quiescent periods, have detrimental effects while short periods are associated with decreased confinement. Following the installation of the all metal ‘ITER like wall’ on JET, sawteeth and ELMs also play an important role by expelling tungsten from the core and edge of the plasma respectively. Control of tungsten has therefore been added to divertor heat load reduction, NTM avoidance and helium ash removal as reasons for requiring ELM and sawtooth control. It is therefore of interest to implement control systems to maintain the sawtooth and ELM frequencies in the desired ranges. On JET, ELM frequency control uses radial field ‘kicks’ and pellet and gas injection as actuators, while sawtooth control uses ion cyclotron resonance heating (ICRH). JET experiments have, for the first time, established feedback control of the ELM frequency, via real time variation of the injected gas flow [1]. Using this controller in conjunction with pellet injection allows the ELM frequency to be kept as required despite variations in pellet ELM triggering efficiency. JET Sawtooth control experiments have, for the first time, demonstrated that low field side ICRH, as foreseen for ITER, can shorten sawteeth lengthened by central fast ions [2]. The development of ELM and sawtooth control could be key to achieve stable high performance JET discharges with minimal tungsten content. Integrating such schemes into an overall control strategy will be required in future tokamaks and gaining experience on current tokamaks is essential.

  19. Optimization of Density and Radiated Power Evolution Control using Magnetic ELM Pace-making in NSTX

    SciTech Connect

    Canik, John; Maingi, Rajesh; Sontag, Aaron C; Bell, R. E.; Gates, D.A.; Gerhardt, S.P.; Kugel, H.; LaBlanc, B. P.; Menard, J.; Paul, S.F.; Sabbagh, S. A.; Soukhanovskii, V. A.

    2010-01-01

    Recent experiments at the National Spherical Torus Experiment (NSTX) have shown that lithium coating of the plasma facing components leads to improved energy confinement, and also the complete suppression of edge-localized modes (ELMs). Due to the lack of ELMs, however, such plasmas suffer from density and radiated power that increase throughout the discharge, often leading to a radiative collapse. Previous experiments have shown that ELMs can be controllably restored into these lithium-conditioned discharges using 3D magnetic perturbations, which reduces impurity accumulation. The use of magnetic ELM pace-making has been optimized to control the evolution of the density and impurity content. Short duration large amplitude 3D field pulses are used, so that the threshold field for destabilization is reached and ELMs triggered quickly, and the field is then removed. A second improvement was made by adding a negative-going pulse to each of the triggering pulses to counteract the vessel eddy currents and reduce time-averaged rotation braking. With these improvements to the triggering waveform, the frequency of the triggered ELMs was increased to over 60 Hz, reducing the average ELM size. The optimum frequency for attaining impurity control while minimizing energy confinement reduction was determined: fairly low frequency ELMs (20 Hz triggering) are sufficient to keep the total radiation fraction below 25% throughout the discharge and avoid radiative collapse, with little reduction in the plasma stored energy. When combined with improved particle fueling, the ELM-pacing technique has been successful in achieving stationary conditions in the line-averaged electron density and total radiated power.

  20. Advances in the physics understanding of ELM suppression using resonant magnetic perturbations in DIII-D

    DOE PAGES

    Wade, M. R.; Nazikian, R.; deGrassie, John S.; ...

    2015-01-14

    Recent experiments on DIII-D have increased confidence in the ability to suppress edge-localized modes (ELMs) using edge-resonant magnetic perturbations (RMPs) in ITER, including an improved physics basis for the edge response to RMPs as well as expansion of RMP ELM suppression to more ITER-like conditions. In this study, complete ELM suppression has been achieved utilizing n = 3 RMPs in the ITER baseline scenario. In addition, RMP ELM suppression has been expanded to include plasmas with helium concentrations near 25% and the use of n = 2 RMPs. Analysis of the kinetic profile response suggests that ELM suppression is correlatedmore » with the co-alignment of the ω⊥e = 0 location, an n = 3 rational surface, and the top of the pedestal. Modelling predicts that such a co-alignment could potentially lead to island (or island chain) formation just inside the top of the pedestal, inhibiting the growth of the pedestal and thereby maintaining the ELM-free state. Detailed analysis of data obtained during toroidal phase variations of the applied n = 3 RMPs have provided further evidence of an island-like structure at the top of the pedestal. In addition, nearly matched discharges with co-neutral-beam-injection (co-NBI) and counter-NBI have demonstrated the importance of the presence of the ω⊥e = 0 location for ELM suppression. Finally, in the counter-NBI cases, the toroidal rotation profile is such that there is no ω⊥e = 0 location and ELMs are not suppressed in conditions in which ELM suppression is generally observed with co-NBI.« less

  1. THE ELM SURVEY. V. MERGING MASSIVE WHITE DWARF BINARIES

    SciTech Connect

    Brown, Warren R.; Kenyon, Scott J.; Kilic, Mukremin; Gianninas, A.; Allende Prieto, Carlos E-mail: skenyon@cfa.harvard.edu E-mail: alexg@nhn.ou.edu

    2013-05-20

    We present the discovery of 17 low-mass white dwarfs (WDs) in short-period (P {<=} 1 day) binaries. Our sample includes four objects with remarkable log g {approx_equal} 5 surface gravities and orbital solutions that require them to be double degenerate binaries. All of the lowest surface gravity WDs have metal lines in their spectra implying long gravitational settling times or ongoing accretion. Notably, six of the WDs in our sample have binary merger times <10 Gyr. Four have {approx}>0.9 M{sub Sun} companions. If the companions are massive WDs, these four binaries will evolve into stable mass transfer AM CVn systems and possibly explode as underluminous supernovae. If the companions are neutron stars, then these may be millisecond pulsar binaries. These discoveries increase the number of detached, double degenerate binaries in the ELM Survey to 54; 31 of these binaries will merge within a Hubble time.

  2. ELM 2016—data update and new functionality of the eukaryotic linear motif resource

    PubMed Central

    Dinkel, Holger; Van Roey, Kim; Michael, Sushama; Kumar, Manjeet; Uyar, Bora; Altenberg, Brigitte; Milchevskaya, Vladislava; Schneider, Melanie; Kühn, Helen; Behrendt, Annika; Dahl, Sophie Luise; Damerell, Victoria; Diebel, Sandra; Kalman, Sara; Klein, Steffen; Knudsen, Arne C.; Mäder, Christina; Merrill, Sabina; Staudt, Angelina; Thiel, Vera; Welti, Lukas; Davey, Norman E.; Diella, Francesca; Gibson, Toby J.

    2016-01-01

    The Eukaryotic Linear Motif (ELM) resource (http://elm.eu.org) is a manually curated database of short linear motifs (SLiMs). In this update, we present the latest additions to this resource, along with more improvements to the web interface. ELM 2016 contains more than 240 different motif classes with over 2700 experimentally validated instances, manually curated from more than 2400 scientific publications. In addition, more data have been made available as individually searchable pages and are downloadable in various formats. PMID:26615199

  3. Hydrologic data for Little Elm Creek, Trinity River basin, Texas, 1976

    USGS Publications Warehouse

    Slade, R.M.; Hays, T.H.; Schoultz, C.T.

    1976-01-01

    This report contains rainfall, runoff, and storage data collected during the 1976 water year for a 75.5 sq mi area above the stream-gaging station Little Elm Creek near Aubrey, Texas. Floodflows from 35.7 sq mi of the area are regulated by 16 floodwater-retarding structures constructed by the Soil Conservation Service. During the 1976 water year, five storm periods were selected for detailed computations and analyses. Beginning with the 1975 water year, water-quality data is given for Little Elm Creek. Investigations in the Little Elm Creek watershed were terminated on September 30, 1976. (Woodard-USGS)

  4. Use Correlation Coefficients in Gaussian Process to Train Stable ELM Models

    DTIC Science & Technology

    2015-05-22

    process · Neural network 1 Introduction Extreme learning machine (ELM) is a special single-hidden layer feed-forward neural network (SLFN) [6]. Due to...2.1 ELM ELM [6] is a single-hidden layer feed-forward neural network (SLFN) and does not require any iterative optimization to input/output weights... Networks with Random Hidden Nodes. IEEE Trans. Neural Netw. 17(4), 879–892 (2006) 4. Huang, G.B., Li, M.B., Chen, L., Siew, C.K.: Incremental Extreme

  5. The Relationship between Type I ELM Severity and Perturbed Electron Transport in NSTX

    NASA Astrophysics Data System (ADS)

    Tritz, Kevin

    2007-11-01

    NSTX provides a unique test bed for probing electron transport due both to its significant role in the steady-state power balance and features of the electron response to transient perturbations. In neutral-beam-heated plasmas in NSTX, most of the heating power is deposited on the electrons. Following large Type I ELMs in some H-mode NSTX discharges, global Te profile declines of 10-30% amplitude are observed. While the soft X-ray data indicates that the ELM itself is causing only a peripheral Te perturbation, the inward propagation of the cold pulse initiated by the ELM is unusually fast (˜ms timescale) and can extend to the core of the plasma. The perturbed electron thermal diffusivity is ˜300 m^2/s for r/a > 0.4, and ˜30 m^2/s for r/a < 0.4. However, in high-triangularity regimes, which exhibit smaller Type I ELM perturbations and an energy loss of a few percent, the perturbation propagation time of several ms implies a perturbed electron thermal diffusivity of 10-20 m^2/s across the plasma radius. Comparison of the ELM energy loss with the electron thermal diffusivity inferred from both ELM and pellet induced `cold pulses', shows a rough proportionality between the ELM magnitude and the perturbed electron thermal diffusivity. Furthermore, comparisons of the linear growth rates of instabilities calculated with the GS2 code show large differences between the large and small Type I ELM regimes. In particular, the ETG mode is the dominant instability following large ELMs, but absent during the small Type I ELM. Interestingly, high-k measurements during ELM events show an increase of short wavelength fluctuations in both the core and edge regions of the plasma, with the increase in amplitude most prominent at wavenumbers of 14-16 cm-1. These results suggest that electron thermal transport plays an important role in determining the total energy loss from Type I ELMs.

  6. LETTER TO THE EDITOR: Were the chaotic ELMs in TCV the result of an ARMA process?

    NASA Astrophysics Data System (ADS)

    Degeling, A. W.; Lister, J. B.; Martin, Y. R.; Zvejnieks, G.

    2004-10-01

    The results of a previous paper claiming the demonstration that edge localized mode (ELM) dynamics on TCV are chaotic in a number of cases has recently been called into question, because the statistical test employed was found to also identify linear auto regressive—moving average (ARMA) models as chaotic. The TCV ELM data has therefore been re-examined with an improved method that is able to make this distinction, and the ARMA model is found to be an inappropriate description of the dynamics on TCV. The hypothesis that ELM dynamics are chaotic on TCV in a number of cases is therefore still favoured.

  7. ELM behaviour and linear MHD stability of edge ECRH heated ASDEX Upgrade plasmas

    NASA Astrophysics Data System (ADS)

    Burckhart, A.; Dunne, M.; Wolfrum, E.; Fischer, R.; McDermott, R.; Viezzer, E.; Willensdorfer, M.; the ASDEX Upgrade Team

    2016-05-01

    In order to test the peeling-ballooning ELM model, ECRH heating was applied to the edge of ASDEX Upgrade type-I ELMy H-mode plasmas to alter the pedestal pressure and current density profiles. The discharges were analysed with respect to ideal MHD stability. While the ELM frequency increased and the pedestal gradients relaxed with edge ECRH, the MHD stability boundary did not change. The results indicate that the peeling-ballooning model is insufficient to fully explain the triggering of ELM instabilities in the presence of edge ECRH heating.

  8. Will Dutch Become Flemish? Autonomous Developments in Belgian Dutch

    ERIC Educational Resources Information Center

    Van de Velde, Hans; Kissine, Mikhail; Tops, Evie; van der Harst, Sander; van Hout, Roeland

    2010-01-01

    In this paper a series of studies of standard Dutch pronunciation in Belgium and the Netherlands is presented. The research is based on two speech corpora: a diachronic corpus of radio speech (1935-1995) and a synchronic corpus of Belgian and Netherlandic standard Dutch from different regions at the turn of the millennium. It is shown that two…

  9. ECE imaging of modified edge localized modes (ELMs) under n=1 magnetic perturbations in KSTAR

    NASA Astrophysics Data System (ADS)

    Lee, Jaehyun; Yun, G. S.; Kim, M.; Choi, M. J.; Lee, W.; Park, H. K.; Lee, J. H.; Jeon, Y. M.; Domier, C. W.; Luhmann, N. C., Jr.; Donné, A. J. H.

    2012-10-01

    In order to control the ELMs in KSTAR H-mode plasmas, magnetic perturbations (MPs) of toroidal mode number n=1 were introduced through three sets of field error correction (FEC) coils [1] during the 2011 campaign. The plasma response was studied in 2-D using electron cyclotron emission imaging (ECEI) diagnostic [2], which showed alteration of both the spatial structure and temporal dynamics of the ELMs. The characteristics of the ELMs such as the growth rate, filament size, and poloidal flow are compared before and after the n=1 MP for various configurations of the FEC coil currents. In particular, the ELM suppression by resonant MP condition is characterized by occasional (non-periodic) tiny transport events, which involve the appearance and crash of transient filament structure localized near the separatrix.[4pt] [1] Y. Jeon et al., accepted for publication in Phys. Rev. Lett.[0pt] [2] G.S. Yun et al., Phys. Rev. Lett., 107, 045004 (2011).

  10. Numerical analysis of key factors for the appearance of grassy ELMs in tokamak plasmas

    NASA Astrophysics Data System (ADS)

    Aiba, N.; Oyama, N.

    2012-11-01

    Numerical stability analysis of edge-localized MHD mode is performed to identify the origin of small-amplitude ‘grassy ELMs’ on the basis of current understanding of kinetic effects on ballooning mode stability. These qualitative and quantitative analyses show that short wavelength ballooning mode can play an important role in a grassy ELM stability even when kinetic effects are taken into account. After showing the importance of kinetic effects for discussing grassy ELM physics, impacts of plasma parameters important for realizing a grassy ELM plasma experimentally are investigated numerically from the viewpoint of the edge-localized MHD stability including these kinetic effects. These analyses show that low plasma ellipticity is preferable to realize a grassy ELM plasma due to destabilizing ballooning mode by preventing access to the second stability region of the ballooning mode.

  11. Study on Sawtooth and ELM activities in DIII-D and KSTAR Plasmas

    NASA Astrophysics Data System (ADS)

    Bak, J.-G.; Kim, H. S.; Lee, S. G.; Lee, K. D.; Ko, W. H.; Kim, J.; Jeon, Y. M.; Kim, W. C.; Bae, Y. S.; Strait, E. J.; La Haye, R. J.; Buttery, R. J.; Wade, M. R.; Park, J. K.; Hanson, J. M.

    2012-10-01

    Sawtooth precursor oscillations (SPOs) are studied in neutral beam heated plasmas on DIII-D and KSTAR. The characteristics of the SPO (5-20 kHz, m/n=1/1) are investigated using magnetic sensors along with electron cyclotron emission (ECE) and soft x-ray diagnostics. In addition, the Type I edge localized mode (ELM) precursors (8-40 kHz, n=2,3) are detected before the ELM burst in neutral beam heated plasmas. The characteristics of the ELM precursors are investigated by using magnetic sensor data. In this work, the experimental investigations of the SPOs and ELM precursors in DIII-D and KSTAR plasmas will be presented.

  12. Half a century of Dutch transplant immunology.

    PubMed

    van Rood, Jon J; Claas, Frans H J; Brand, Anneke; Tilanus, Marcel G J; van Kooten, Cees

    2014-12-01

    The sixties have not only witnessed the start of the Dutch Society for Immunology (NvvI), but were also the flourishing beginning of the discipline of transplant immunology. The interest in immunology in the Netherlands had its start in the context of blood transfusions and not for instance in the field of infectious disease, as in many other countries. It began in the 1950-ties thanks to Joghem van Loghem at that time director of the Central Laboratory of Blood Transfusion in Amsterdam. The discoveries of these times have had major impact for transfusion medicine, hematopoietic stem cell transplantation and organ transplantation. In this review we will look back at some early highlights of Dutch transplant immunology and put them in the perspective of some recent developments.

  13. Hydrologic data for Little Elm Creek, Trinity River basin, Texas, 1975

    USGS Publications Warehouse

    Slade, R.M.; Taylor, J.M.

    1977-01-01

    This report contains rainfall, runoff, and storage data collected during the 1975 water year for a 75.5 sq mi area above the stream-gaging station Little Elm Creek near Aubrey, Texas. Floodflows from 35.7 sq mi of the area are regulated by 16 floodwater-retarding structures constructed by the Soil Conservation Service. Six storm periods were selected for detailed computations and analyses. Water-quality data is given for Little Elm Creek. (Woodard-USGS)

  14. ELM-related fluctuations in PBX-M H-modes

    SciTech Connect

    Kaye, S.M.; Hahm, T.S.; Sesnic, S.; Tang, W.; Roney, P.; Davis, W.; Dunlap, J.L.; Harris, J.H.

    1994-04-01

    Edge Localized Modes, or ELMs, are at the same time both disadvantageous and advantageous features of H-modes. ELMs can cause energy and particle losses from the plasma, with instantaneous energy losses reaching 40% of the total stored energy in the case of large-amplitude ELMs. The energy loss from these ELMs, or closely spaced smaller ELMs, may result in what is known as a beta-collapse, an event in which energy is lost over a substantial duration of the discharge. On the other hand, if controlled, the ELM related energy and, especially, impurity losses can lead to near steady-state discharge conditions with relatively low radiative power losses. The importance of ELMs in the development of the H-phase has led to numerous studies which attempt to uncover their nature. The purpose of the present work is to present additional observations of, most notably, high frequency magnetic fluctuations associated with ELMS. There are some observations here that are consistent with previously reported ones, namely the appearance of high frequency ({ge}250 kHz) activity prior to the D{sub {alpha}} increase, suggesting again that the rise in D{sub {alpha}} is some delayed response to an instability occurring farther inside the plasma edge. While this high frequency activity is global, with high coherence for all coil pairs both on the inside and outside midplane, there is no identifiable mode structure. Reported here for the first time are observations of a very intense outward ballooning feature that appears simultaneously with the D{sub {alpha}} increase and lasts for about 5 msec. The toroidal mode structure of this feature is clearly identifiable, consisting of a series of toroidal harmonics from n=3 to 8, at frequencies given by f{sub n}=f{sub 0}+n{Delta}f, with f{sub 0}=30 to 50 kHz and A{Delta}=20 to 30 kHz.

  15. Pennsylvania Dutch Crafts and Culture

    ERIC Educational Resources Information Center

    Turner, Dianne

    2008-01-01

    Many people hold two common misconceptions about the Pennsylvania Dutch: first, that these people live exclusively in the state of Pennsylvania; second, that their ancestors came from Holland. However, neither assumption is correct. One can find large Pennsylvania Dutch communities in Mary land, West Virginia, Virginia, the Carolinas, Ohio,…

  16. Divertor heat loads in RMP ELM controlled H-mode plasmas on DIII-D*

    SciTech Connect

    Jakubowski, M; Lasnier, C; Schmitz, O; Evans, T; Fenstermacher, M; Groth, M; Watkins, J; Eich, T; Moyer, R; Wolf, R; Baylor, L; Boedo, J; Burrell, K; Frerichs, H; deGrassie, J; Gohil, P; Joseph, I; Lehnen, M; Leonard, A; Petty, C; Pinsker, R; Reiter, D; Rhodes, T; Samm, U; Snyder, P; Stoschus, H; Osborne, T; Unterberg, B; West, W

    2008-10-13

    In this paper the manipulation of power deposition on divertor targets at DIII-D by application of resonant magnetic perturbations (RMPs) is analyzed. It has been found that heat transport shows a different reaction to the applied RMP depending on the plasma pedestal collisionality. At pedestal electron collisionality above 0.5 the heat flux during the ELM suppressed phase is of the same order as the inter-ELM in the non-RMP phase. Below this collisionality value we observe a slight increase of the total power flux to the divertor. This can be caused by much more negative potential at the divertor surface due to hot electrons reaching the divertor surface from the pedestal area and/or so called pump out effect. In the second part we discuss modification of ELM behavior due to the RMP. It is shown, that the width of the deposition pattern in ELMy H-mode depends linearly on the ELM deposited energy, whereas in the RMP phase of the discharge those patterns seem to be controlled by the externally induced magnetic perturbation. D{sub 2} pellets injected into the plasma bulk during ELM-free RMP H-mode lead in some cases to a short term small transients, which have very similar properties to ELMs in the initial RMP-on phase.

  17. ELM triggering by energetic particle driven mode in wall-stabilized high-β plasmas

    NASA Astrophysics Data System (ADS)

    Matsunaga, G.; Aiba, N.; Shinohara, K.; Asakura, N.; Isayama, A.; Oyama, N.; the JT-60 Team

    2013-07-01

    In the JT-60U high-β plasmas above the no-wall β limit, a triggering of an edge localized mode (ELM) by an energetic particle (EP)-driven mode has been observed. This EP-driven mode is thought to be driven by trapped EPs and it has been named EP-driven wall mode (EWM) on JT-60U (Matsunaga et al 2009 Phys. Rev. Lett. 103 045001). When the EWM appears in an ELMy H-mode phase, ELM crashes are reproducibly synchronized with the EWM bursts. The EWM-triggered ELM has a higher repetition frequency and less energy loss than those of the natural ELM. In order to trigger an ELM by the EP-driven mode, some conditions are thought to be needed, thus an EWM with large amplitude and growth rate, and marginal edge stability. In the scrape-off layer region, several measurements indicate an ion loss induced by the EWM. The ion transport is considered as the EP transport through the edge region. From these observations, the EP contributions to edge stability are discussed as one of the ELM triggering mechanisms.

  18. Study of the spectral properties of ELM precursors by means of wavelets

    NASA Astrophysics Data System (ADS)

    Poli, F. M.; Sharapov, S. E.; Chapman, S. C.; Contributors, JET-EFDA

    2008-09-01

    The high confinement regime (H-mode) in tokamaks is accompanied by the occurrence of bursts of MHD activity at the plasma edge, so-called edge localized modes (ELMs), lasting less than 1 ms. These modes are often preceded by coherent oscillations in the magnetic field, the ELM precursors, whose mode numbers along the toroidal and the poloidal directions can be measured from the phase shift between Mirnov pickup coils. When the ELM precursors have a lifetime shorter than a few milliseconds, their toroidal mode number and their nonlinear evolution before the ELM crash cannot be studied reliably with standard techniques based on Fourier analysis, since averaging in time is implicit in the computation of the Fourier coefficients. This work demonstrates significant advantages in studying spectral features of the short-lived ELM precursors by using Morlet wavelets. It is shown that the wavelet analysis is suitable for the identification of the toroidal mode numbers of ELM precursors with the shortest lifetime, as well as for studying their nonlinear evolution with a time resolution comparable to the acquisition rate of the Mirnov coils.

  19. Identification and control of nonlinear system based on Laguerre-ELM Wiener model

    NASA Astrophysics Data System (ADS)

    Tang, Yinggan; Han, Zhenzhen; Liu, Fucai; Guan, Xinping

    2016-09-01

    In this paper, a new Wiener model is presented for identification and control of single-input single-output (SISO) nonlinear systems. The proposed Wiener model consists of a linear Laguerre filter in cascaded with an extreme learning machine (ELM) neural network (called Laguerre-ELM Wiener model). Laguerre filter can approximate a stable linear system to any degree of accuracy with a small number of Laguerre filters, which provides a parsimony structure and high level accuracy simultaneously. To determine the appropriated number of Laguerre filters in Laguerre-ELM Wiener model, Lipschitz quotient criterion is adapted to determine the order of linear part. A generalized ELM algorithm is proposed to estimate the parameters of Laguerre-ELM Wiener model. Once the unknown nonlinear system is identified using Laguerre-ELM Wiener model, a generalized predictive control (GPC) algorithm is designed for control of nonlinear system. The advantage of the proposed control method is that it transfers a nonlinear control problem to a linear one by inserting the inverse of static nonlinear section. Simulation results demonstrate the effectiveness of the proposed identification and control algorithms.

  20. Numerical investigation of plasma-wall interaction during burst of ELMs in a tokamak device

    NASA Astrophysics Data System (ADS)

    Ou, Jing; Lin, Binbin; Zhao, Xiaoyun

    2017-01-01

    In the tokamak high confinement mode (H-mode), the transient heat fluxes caused by edge localized modes (ELMs) will eventually irradiate the plasma-facing components and may erode, even melt them. To study the performance of the plasma-wall interaction during ELMs, interactions among heat flux from plasma, surface temperature, and electron emission are simulated by considering self-consistency among plasma transport in the sheath, deposited heat at the wall, and material thermal response for carbon (C) and tungsten (W) walls. It is found that the sheath structure determines the surface temperature, which may in turn influence on the sheath. A large amount of electron emission can change the heat load from the plasma to the material surface due to the variation of the ELMs-induced electron temperature and the surface temperature. During the burst of ELMs, the surface temperature rises rapidly at first and then reaches a saturation state with a certain range of fluctuation. The development of these processes depends strongly on the characteristic of ELMs, deposited heat at the wall, and material properties. Simulation results also show that the erosion of the Experimental Advanced Superconducting Tokamak (EAST) divertor target is of no concern in H-mode operation with ELMs for the current and possible future operation parameters.

  1. Evolution of the 2D Spatial Profile of Visible Emission During an ELM in the DIII-D Divertor

    NASA Astrophysics Data System (ADS)

    Fenstermacher, M. E.; Groth, M.; Lasnier, C. J.; Boedo, J. C.; Leonard, A. W.

    2001-10-01

    The transient particle and energy loads due to Edge Localized Modes (ELMs) are a significant problem for the design of divertors in future tokamak reactors. Detailed understanding of the effect of the ELM perturbation on the 2D distribution of radiation in the divertor is needed to validate computer simulations and investigate mitigation schemes. Gated, intensified, tangentially viewing cameras with wavelength filters were used in combination with tomographic reconstruction techniques to provide 2D profiles of carbon and deuterium emission during ELM evolution in the DIII-D divertor. Preliminary 2D reconstructions of D_α and CIII visible emission during large Type-I ELMs will be shown. The dramatic broadening of the D_α emission profile near the target will be compared with the broadening of the heat flux profiles during ELMs from IRTV. Plans for obtaining the detailed temporal evolution of the 2D spatial profile of the divertor emission throughout an ELM will be described.

  2. Turbulence Dynamics During RMP-ELM Suppressed Discharges

    NASA Astrophysics Data System (ADS)

    McKee, G. R.; Yan, Z.; Schmitz, O.; Buttery, R. J.; Evans, T. E.; Wade, M. R.; Schmitz, L.; Moyer, R. A.

    2011-10-01

    Long-wavelength density fluctuations in the plasma edge region (0 . 75 < r / a < 1 . 0) change markedly in response to applied resonant magnetic field perturbations, used to suppress ELMs. The RMP-enhanced fluctuations, measured with a 2D array of BES channels, have a radial correlation length of a few cm and span 50-400 kHz in frequency. Modulated RMPs are used to examine the fast temporal dynamics of the turbulence and related parameters. Inside of the pedestal (0 . 8 < r / a < 0 . 9), turbulence is found to change rapidly with the applied RMP, with a few ms response time, suggesting that enhanced turbulence may play a causative role in the observed increased particle and momentum transport. Fluctuations in the pedestal region exhibit a more complex response, initially decreasing with reduced RMP, but subsequently increasing as the pedestal pressure gradient increases. New measurements from upcoming experiments on the q95 dependence of the turbulence and flow response to RMPs will also be presented. Work supported in part by US DOE under DE-FG02-08ER54999, DE-FG02-89ER53296, DE-FC02-04ER54698, DE-FG02-08ER54984, and DE-FG02-07ER54917.

  3. Pruning The ELM Survey: Characterizing Candidate Low-mass White Dwarfs through Photometric Variability

    NASA Astrophysics Data System (ADS)

    Bell, Keaton J.; Gianninas, A.; Hermes, J. J.; Winget, D. E.; Kilic, Mukremin; Montgomery, M. H.; Castanheira, B. G.; Vanderbosch, Z.; Winget, K. I.; Brown, Warren R.

    2017-02-01

    We assess the photometric variability of nine stars with spectroscopic Teff and log g values from the ELM Survey that locates them near the empirical extremely low-mass (ELM) white dwarf instability strip. We discover three new pulsating stars: SDSS J135512.34+195645.4, SDSS J173521.69+213440.6, and SDSS J213907.42+222708.9. However, these are among the few ELM Survey objects that do not show radial velocity (RV) variations that confirm the binary nature expected of helium-core white dwarfs. The dominant 4.31 hr pulsation in SDSS J135512.34+195645.4 far exceeds the theoretical cut-off for surface reflection in a white dwarf, and this target is likely a high-amplitude δ Scuti pulsator with an overestimated surface gravity. We estimate the probability to be less than 0.0008 that the lack of measured RV variations in four of eight other pulsating candidate ELM white dwarfs could be due to low orbital inclination. Two other targets exhibit variability as photometric binaries. Partial coverage of the 19.342 hr orbit of WD J030818.19+514011.5 reveals deep eclipses that imply a primary radius >0.4 R⊙—too large to be consistent with an ELM white dwarf. The only object for which our time series photometry adds support to ELM white dwarf classification is SDSS J105435.78‑212155.9, which has consistent signatures of Doppler beaming and ellipsoidal variations. We conclude that the ELM Survey contains multiple false positives from another stellar population at Teff ≲ 9000 K, possibly related to the sdA stars recently reported from SDSS spectra.

  4. H-Mode Turbulence, Power Threshold, ELM, and Pedestal Studies in NSTX

    SciTech Connect

    R. Maingi; C.E. Bush; E.D. Fredrickson; D.A. Gates; S.M. Kaye; B.P. LeBlanc; J.E. Menard; H. Meyer; D. Mueller; N. Nishino; A.L. Roquemore; S.A. Sabbagh; K. Tritz; S.J. Zweben; M.G. Bell; R.E. Bell; T. Biewer; J.A. Boedo; D.W. Johnson; R. Kaita; H.W. Kugel; R.J. Maqueda; T. Munsat; R. Raman; V.A. Soukhanovskii; T. Stevenson; D. Stutman

    2004-10-28

    High-confinement mode (H-mode) operation plays a crucial role in NSTX [National Spherical Torus Experiment] research, allowing higher beta limits due to reduced plasma pressure peaking, and long-pulse operation due to high bootstrap current fraction. Here, new results are presented in the areas of edge localized modes (ELMs), H-mode pedestal physics, L-H turbulence, and power threshold studies. ELMs of several other types (as observed in conventional aspect ratio tokamaks) are often observed: (1) large, Type I ELMs, (2) ''medium'' Type II/III ELMs, and (3) giant ELMs which can reduce stored energy by up to 30% in certain conditions. In addition, many high-performance discharges in NSTX have tiny ELMs (newly termed Type V), which have some differences as compared with ELM types in the published literature. The H-mode pedestal typically contains between 25-33% of the total stored energy, and the NSTX pedestal energy agrees reasonably well with a recent international multi-machine scaling. We find that the L-H transition occurs on a {approx}100 {micro}sec timescale as viewed by a gas puff imaging diagnostic, and that intermittent quiescent periods precede the final transition. A power threshold identity experiment between NSTX and MAST shows comparable loss power at the L-H transition in balanced double-null discharges. Both machines require more power for the L-H transition as the balance is shifted toward lower single null. High field side gas fueling enables more reliable H-mode access, but does not always lead to a lower power threshold e.g., with a reduction of the duration of early heating. Finally the edge plasma parameters just before the L-H transition were compared with theories of the transition. It was found that while some theories can separate well-developed L- and H-mode data, they have little predictive value.

  5. Ulmus americana is a polyploid complex

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The elms (the genus Ulmus) are one of the most important tree crops for the $4.7-billion per year nursery industry. The commercial importance of the genus centers on the American elm, Ulmus americana. Once decimated by Dutch Elm Disease, the recent introduction of cultivars resistant to the diseas...

  6. ELM Behavior in High- βp EAST-Demonstration Plasmas on DIII-D

    NASA Astrophysics Data System (ADS)

    Li, G. Q.; Gong, X. Z.; Garofalo, A. M.; Lao, L. L.; Meneghini, O.; Snyder, P. B.; Ren, Q. L.; Ding, S. Y.; Guo, W. F.; Qian, J. P.; Wan, B. N.; Xu, G. S.; Holcomb, C. T.; Solomon, W. M.

    2015-11-01

    In the DIII-D high- βp EAST-demonstration experiment, for several similar discharges when the experimental parameters such as the toroidal magnetic field or ECH power are varied slightly, the changes in ELM frequency response are observed to be much larger. Kinetic EFIT equilibrium reconstructions for these discharges have been performed, which suggest that the ELM frequency changes are likely due to the variations of pedestal width, height, and edge current density. Kinetic profile analyses further indicate that the strong ITB that are located at large minor radii (rho=0.6 ~0.7) in these discharges are affecting the pedestal structure. The ITB could broaden the pedestal width and decrease the pedestal height, thus changing the ELM frequency and size. With the GATO and ELITE MHD codes, the linear growth rates and mode structures of these ELMs are analyzed. The impact of ITB on the ELMs behavior will be discussed. Work supported by China MOST under 2014GB106001 and 2015GB102001 and US DOE under DE-FC02-04ER54698 and DE-FG03-95ER54309.

  7. Broadening of divertor heat flux profile with increasing number of ELM filaments in NSTX

    NASA Astrophysics Data System (ADS)

    Ahn, J.-W.; Maingi, R.; Canik, J. M.; Gan, K. F.; Gray, T. K.; McLean, A. G.

    2014-12-01

    Edge localized modes (ELMs) represent a challenge to future fusion devices, owing to cyclical high peak heat fluxes on divertor plasma facing surfaces. One ameliorating factor has been that the heat flux characteristic profile width has been observed to broaden with the size of the ELM, as compared with the inter-ELM heat flux profile. In contrast, the heat flux profile has been observed to narrow during ELMs under certain conditions in NSTX. Here we show that the ELM heat flux profile width increases with the number of filamentary striations observed, i.e. profile narrowing is observed with zero or very few striations. Because NSTX often lies on the long wavelength current-driven mode side of ideal MHD instabilities, few filamentary structures can be expected under many conditions. ITER is also projected to lie on the current driven low-n stability boundary, and therefore detailed projections of the unstable modes expected in ITER and the heat flux driven in ensuing filamentary structures is needed.

  8. Turbulence, flows and edge localized mode (ELM) dynamics in limiter H-mode plasmas in TEXTOR

    NASA Astrophysics Data System (ADS)

    Soldatov, S.; Krämer-Flecken, A.; Kantor, M.; Unterberg, B.; Sun, Y.; Van Oost, G.; Reiter, D.; TEXTOR Team

    2010-08-01

    The turbulence, plasma flow and edge localized mode (ELM) dynamics in the limiter H-mode TEXTOR plasmas are investigated. Properties of both ambient turbulence within 0 < k⊥ < 4.2 cm-1 and coherent modes are studied on the ELM time scale in detail. The turbulence level near the pedestal is shown to evolve several times with the period of ELMs. Within the inter-ELM period the 'silent stage' is found which is characterized by an extremely low (below that for Ohmic plasmas) turbulence level and a phase growth in the reflectometry signal. The silent stage is associated with the quasi-steady state when the pedestal is formed and confinement is improved between two successive ELMs. Quasi-coherent density oscillations near the pedestal region with m ≈ 3, 5, 16 and 38 are measured with correlation reflectometry. Low-m modes are found to reveal the signatures of precursor mode. At first, the radial structure of the rotation shear and radial electric field Er in limiter H-mode in TEXTOR is presented. The characteristic negative electric field well with the sharp gradient ∇Er ≈ 250 V cm-2 at ≈2 cm inside separatrix is resolved. The Er × B rotation profile defines both the resulting plasma rotation in the electron diamagnetic drift direction and a significant rotation shear near the separatrix which exceeds the decorrelation rate of ambient turbulence by several times.

  9. Broadening of divertor heat flux profile with increasing number of ELM filaments in NSTX

    SciTech Connect

    Ahn, J. -W.; Maingi, R.; Canik, J. M.; Gan, K. F.; Gray, T. K.; McLean, A. G.

    2014-11-13

    Edge localized modes (ELMs) represent a challenge to future fusion devices, owing to cyclical high peak heat fluxes on divertor plasma facing surfaces. One ameliorating factor has been that the heat flux characteristic profile width has been observed to broaden with the size of the ELM, as compared with the inter-ELM heat flux profile. In contrast, the heat flux profile has been observed to narrow during ELMs under certain conditions in NSTX. Here we show that the ELM heat flux profile width increases with the number of filamentary striations observed, i.e., profile narrowing is observed with zero or very few striations. Because NSTX often lies on the long wavelength current-driven mode side of ideal MHD instabilities, few filamentary structures can be expected under many conditions. Lastly, ITER is also projected to lie on the current driven low-n stability boundary, and therefore detailed projections of the unstable modes expected in ITER and the heat flux driven in ensuing filamentary structures is needed.

  10. Broadening of divertor heat flux profile with increasing number of ELM filaments in NSTX

    DOE PAGES

    Ahn, J. -W.; Maingi, R.; Canik, J. M.; ...

    2014-11-13

    Edge localized modes (ELMs) represent a challenge to future fusion devices, owing to cyclical high peak heat fluxes on divertor plasma facing surfaces. One ameliorating factor has been that the heat flux characteristic profile width has been observed to broaden with the size of the ELM, as compared with the inter-ELM heat flux profile. In contrast, the heat flux profile has been observed to narrow during ELMs under certain conditions in NSTX. Here we show that the ELM heat flux profile width increases with the number of filamentary striations observed, i.e., profile narrowing is observed with zero or very fewmore » striations. Because NSTX often lies on the long wavelength current-driven mode side of ideal MHD instabilities, few filamentary structures can be expected under many conditions. Lastly, ITER is also projected to lie on the current driven low-n stability boundary, and therefore detailed projections of the unstable modes expected in ITER and the heat flux driven in ensuing filamentary structures is needed.« less

  11. Comparison of Plasma Parameters Between QH and ELMing Phases of the Same Discharges

    SciTech Connect

    Lasnier, C; West, W; Burrell, K; deGrassie, J; Doyle, E; Osborne, T

    2004-05-24

    H-mode confinement is observed for many energy confinement times without edge localized modes (ELMs) in QH (quiescent high-confinement)-mode discharges in DIII-D. To find critical differences between ELMing and QH modes we compared electron temperature (T{sub e}), density (n{sub e}), and ion temperature (T{sub i}), in the pedestal and scrape-off layer (SOL) for a group of discharges. We also compared the electron pressures P{sub ped}, and maximum pressure gradients P{sub e,ped,max grad} because of their importance in confinement and stability. Experimental results show that the core line averaged density, median T{sub e} (pedestal), SOL T{sub e}, and T{sub e} pedestal width, and SOL T{sub i} are nearly the same in QH mode as that during ELMs. The n{sub e} (average pedestal), n{sub e} pedestal width, P{sub ped}, and P{sub e,ped,max grad} are similar to corresponding values in QH mode and at various times between ELMs. However, the pedestal T{sub i} is 1.6 times higher in QH mode than during ELMing.

  12. Elm1 kinase activates the spindle position checkpoint kinase Kin4

    PubMed Central

    Caydasi, Ayse Koca; Kurtulmus, Bahtiyar; Orrico, Maria I.L.; Hofmann, Astrid; Ibrahim, Bashar

    2010-01-01

    Budding yeast asymmetric cell division relies upon the precise coordination of spindle orientation and cell cycle progression. The spindle position checkpoint (SPOC) is a surveillance mechanism that prevents cells with misoriented spindles from exiting mitosis. The cortical kinase Kin4 acts near the top of this network. How Kin4 kinase activity is regulated and maintained in respect to spindle positional cues remains to be established. Here, we show that the bud neck–associated kinase Elm1 participates in Kin4 activation and SPOC signaling by phosphorylating a conserved residue within the activation loop of Kin4. Blocking Elm1 function abolishes Kin4 kinase activity in vivo and eliminates the SPOC response to spindle misalignment. These findings establish a novel function for Elm1 in the coordination of spindle positioning with cell cycle progression via its control of Kin4. PMID:20855503

  13. A novel classification method based on ICA and ELM: a case study in lie detection.

    PubMed

    Xiong, Yijun; Luo, Yu; Huang, Wentao; Zhang, Wenjia; Yang, Yong; Gao, Junfeng

    2014-01-01

    The classification of EEG tasks has drawn much attention in recent years. In this paper, a novel classification model based on independent component analysis (ICA) and Extreme learning machine (ELM) is proposed to detect lying. Firstly, ICA and its topography information were used to automatically identify the P300 ICs. Then, time and frequency-domain features were extracted from the reconstructed P3 waveforms. Finally, two classes of feature samples were used to train ELM, Back-propagation network (BPNN) and support vector machine (SVM) classifiers for comparison. The optimal number of P3 ICs and the values of classifier parameter were optimized by the cross-validation procedures. Experimental results show that the presented method (ICA_ELM) achieves the highest training accuracy of 95.40% with extremely less training and testing time on detecting P3 components for the guilty and the innocent subjects. The results indicate that the proposed method can be applied in lie detection.

  14. Compound feature selection and parameter optimization of ELM for fault diagnosis of rolling element bearings.

    PubMed

    Luo, Meng; Li, Chaoshun; Zhang, Xiaoyuan; Li, Ruhai; An, Xueli

    2016-11-01

    This paper proposes a hybrid system named as HGSA-ELM for fault diagnosis of rolling element bearings, in which real-valued gravitational search algorithm (RGSA) is employed to optimize the input weights and bias of ELM, and the binary-valued of GSA (BGSA) is used to select important features from a compound feature set. Three types fault features, namely time and frequency features, energy features and singular value features, are extracted to compose the compound feature set by applying ensemble empirical mode decomposition (EEMD). For fault diagnosis of a typical rolling element bearing system with 56 working condition, comparative experiments were designed to evaluate the proposed method. And results show that HGSA-ELM achieves significant high classification accuracy compared with its original version and methods in literatures.

  15. Biomass properties and gasification behavior of 7-year-old Siberian elm

    SciTech Connect

    Geyer, W.A.; Argent, R.M.; Walawender, W.P.

    1987-04-01

    Studies were conducted to establish baseline information for use in characterizing Siberian elm as energy or fiber feedstock. Biomass properties were determined. Calorific value (4698 cal/g) and specific gravity (0.55) of Siberian elm are similar to those of soft elms, and its fiber length is relatively short (1.00 mm). Ash content was 1.65%. Gasification produces a medium energy gas (3 x 10/sup 6/ cal/cubic m) with yield varying from 0.17 to 0.96 cubic m/kg over a gasification temperature range of 600 to 700 C. Oven-dry yields were 9.8 t/ha annually at 700 trees/ha. 23 references.

  16. Elm1 kinase activates the spindle position checkpoint kinase Kin4.

    PubMed

    Caydasi, Ayse Koca; Kurtulmus, Bahtiyar; Orrico, Maria I L; Hofmann, Astrid; Ibrahim, Bashar; Pereira, Gislene

    2010-09-20

    Budding yeast asymmetric cell division relies upon the precise coordination of spindle orientation and cell cycle progression. The spindle position checkpoint (SPOC) is a surveillance mechanism that prevents cells with misoriented spindles from exiting mitosis. The cortical kinase Kin4 acts near the top of this network. How Kin4 kinase activity is regulated and maintained in respect to spindle positional cues remains to be established. Here, we show that the bud neck-associated kinase Elm1 participates in Kin4 activation and SPOC signaling by phosphorylating a conserved residue within the activation loop of Kin4. Blocking Elm1 function abolishes Kin4 kinase activity in vivo and eliminates the SPOC response to spindle misalignment. These findings establish a novel function for Elm1 in the coordination of spindle positioning with cell cycle progression via its control of Kin4.

  17. Collapse of density pedestal by giant ELM on JT-60U

    NASA Astrophysics Data System (ADS)

    Oyama, N.; Shinohara, K.; Kamada, Y.; Miura, Y.; Oikawa, T.; Takeji, S.

    2001-05-01

    In JT-60U ELMy H-mode discharges, the detailed behaviour of giant (type I) ELMs was measured using a heterodyne reflectometer system in order to understand the collapse mechanism of the pedestal structure and consequences on the core/edge plasma. The phase signal of the reflectometer exhibits the movement of the cutoff layer (density layer) due to the collapse of the pedestal in a density profile by an ELM. An ELM event can be classified into a precursor phase, collapse phase, recovery phase and a relaxation phase. A certain density layer measured near the shoulder of the pedestal moves about 7 cm inside the plasma in the collapse phase. The precursor oscillation in a pedestal density and the relationship between the collapse of the pedestal structure and a Dα burst are also studied.

  18. New Grid of Models for ELM WDs Including Element Diffusion and Rotational Mixing

    NASA Astrophysics Data System (ADS)

    Istrate, A. G.

    2017-03-01

    We present our latest results for the modelling of extremely low-mass white dwarfs (ELM WDs) in which, for the first time, we study the combined effects of rotational mixing and element diffusion. In particular, we investigate how their general properties, such as their evolutionary timescales, the hydrogen envelope mass and their surface composition are affected compared to the case when just element diffusion is included. The formation of ELM WDs through the LMXB channel in environments with different metallicities is modelled using the state-of-the-art stellar evolution code MESA. Rotational mixing is found to counteract the effect of gravitational settling in the surface of young, bloated ELM proto-WDs suggesting that it is the key process needed to explain the observed metals (especially calcium) abundances in their atmospheres.

  19. Semiochemical-MediatedFlight Strategies of Two Invasive Elm Bark Beetles: A Potential Factor in Competitive Displacement

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A recent seven-state survey revealed that the newly invasive banded elm bark beetle, Scolytus schevyrewi, was abundant in areas of Colorado and Wyoming, USA, whereas the long-established European elm bark beetle, S. multistriatus was not as abundant. Behavioral trials were conducted by hanging sm...

  20. Numerical Analysis of the Effects of Normalized Plasma Pressure on RMP ELM Suppression in DIII-D

    SciTech Connect

    Orlov, D. M.; Moyer, R.A.; Evans, T. E.; Mordijck, S.; Osborne, T. H.; Fenstermacher, M. E.; Snyder, P. B.; Unterberg, Ezekial A

    2010-01-01

    The effect of normalized plasma pressure as characterized by normalized pressure parameter (beta(N)) on the suppression of edge localized modes (ELMs) using resonant magnetic perturbations (RMPs) is studied in low-collisionality (nu* <= 0.2) H-mode plasmas with low-triangularity ( = 0.25) and ITER similar shapes ( = 0.51). Experimental results have suggested that ELM suppression by RMPs requires a minimum threshold in plasma pressure as characterized by beta(N). The variations in the vacuum field topology with beta(N) due to safety factor profile and island overlap changes caused by variation of the Shafranov shift and pedestal bootstrap current are examined numerically with the field line integration code TRIP3D. The results show very small differences in the vacuum field structure in terms of the Chirikov (magnetic island overlap) parameter, Poincare sections and field line loss fractions. These differences do not appear to explain the observed threshold in beta(N) for ELM suppression. Linear peeling-ballooning stability analysis with the ELITE code suggests that the ELMs which persist during the RMPs when beta(N) is below the observed threshold are not type I ELMs, because the pedestal conditions are deep within the stable regime for peeling-ballooning modes. These ELMs have similarities to type III ELMs or low density ELMs.

  1. Toroidal Rotation and 3D Nonlinear Dynamics in the Peeling-Ballooning Model of ELMs

    NASA Astrophysics Data System (ADS)

    Snyder, P. B.

    2004-11-01

    Maximizing the height of the edge transport barrier (or ``pedestal'') while maintaining acceptably small edge localized modes (ELMs) is a critical issue for tokamak performance. The peeling-ballooning model proposes that intermediate wavelength MHD instabilities are responsible for ELMs and impose constraints on the pedestal. Recent studies of linear peeling-ballooning stability have found encouraging agreement with observations [e.g. 1]. To allow more detailed prediction of mode characteristics, including eventually predictions of the ELM energy loss and its deposition, we consider effects of sheared toroidal rotation, as well as 3D nonlinear dynamics. An eigenmode formulation for toroidal rotation shear is developed and incorporated into the framework of the ELITE stability code [2], resolving the low rotation discontinuity in previous high-n results. Rotation shear is found to impact the structure of peeling-ballooning modes, causing radial narrowing and mode shearing. The calculated mode frequency is found to agree with observed rotation in the edge region in the early stages of the ELM crash. Nonlinear studies with the 3D BOUT and NIMROD codes reveal detailed characteristics of the early evolution of these edge instabilities, including the impact of non-ideal effects. The expected linear growth phase is followed by a fast crash event in which poloidally narrow, filamentary structures propagate radially outward from the pedestal region, closely resembling observed ELM events. Comparisons with ELM observations will be discussed. \\vspace0.25em [1] P.B. Snyder et al., Nucl. Fusion 44, 320 (2004); P.B. Snyder et al., Phys. Plasmas 9, 2037 (2002). [2] H.R. Wilson et al., Phys. Plasmas 9, 1277 (2002).

  2. Pedestal characterization and stability of small-ELM regimes in NSTX

    SciTech Connect

    Sontag, Aaron C; Canik, John; Maingi, Rajesh; Manickam, J.; Snyder, P.; Bell, R. E.; Gerhardt, S.P.; Kubota, S.; LaBlanc, B. P.; Mueller, D.; Osborne, T.; Tritz, K.

    2011-01-01

    An instability near the plasma edge known as the edge harmonic oscillation (EHO) is thought to enable access to the ELM-free quiescent H-mode (QH-mode) in tokamaks, which is a highly desirable operational regime for ITER because of the avoidance of periodic ELM heat loads. The EHO has been hypothesized to be a saturated kink driven unstable by toroidal rotational shear that provides sufficient transport near the plasma edge to keep the edge plasma below the peeling-ballooning stability limit. NSTX has observed unstable modes with similar characteristics to the EHO coincident with transition to a small-ELM regime (called Type-V). These small ELMs do not have a measurable effect on the plasma stored energy (< 1%). Transition to this regime is associated with a downward biased plasma as evidenced by drsep < -5 mm. Soft x-ray emission indicates that these modes are localized just inside the pedestal and are correlated with increased density fluctuations in the pedestal as measured by microwave reflectometry. The lowest order mode rotates at the plasma rotation frequency, indicating n=1, and harmonics up to n=6 have been observed simultaneously with the n=1, as determined by the rotation frequency of the higher harmonics. Increased edge collisionality is required to access Type-V ELMs. Stability analysis during the observed modes indicates instability to n=1-3 with n=3 having the highest growth rate and unstable mode eigenfunctions peaked near the plasma edge. Discharges with Type-V and Type-I ELMs are both calculated to be on the peeling unstable side of the peeling ballooning stability curve, with the Type-V case at higher normalized pressure gradient.

  3. Pedestal Characterization and Stability of Small-ELM Regimes in NSTX

    SciTech Connect

    Sontag, Aaron C; Canik, John; Maingi, Rajesh; Manickam, J.; Snyder, P.; Bell, R. E.; Gerhardt, S.P.; Kubota, S.; LaBlanc, B. P.; Mueller, D.; Osborne, T.; Tritz, K.

    2010-01-01

    An instability near the plasma edge known as the edge harmonic oscillation (EHO) is thought to enable access to the ELM-free quiescent H-mode (QH-mode) in tokamaks, which is a highly desirable operational regime for ITER because of the avoidance of periodic ELM heat loads. The EHO has been hypothesized to be a saturated kink driven unstable by toroidal rotational shear that provides sufficient transport near the plasma edge to keep the edge plasma below the peeling-ballooning stability limit. NSTX has observed unstable modes with similar characteristics to the EHO coincident with transition to a small-ELM regime (called Type-V). These small ELMs do not have a measurable effect on the plasma stored energy (< 1%). Transition to this regime is associated with a downward biased plasma as evidenced by drsep < -5 mm. Soft x-ray emission indicates that these modes are localized just inside the pedestal and are correlated with increased density fluctuations in the pedestal as measured by microwave reflectometry. The lowest order mode rotates at the plasma rotation frequency, indicating n=1, and harmonics up to n=6 have been observed simultaneously with the n=1, as determined by the rotation frequency of the higher harmonics. Increased edge collisionality is required to access Type-V ELMs. Stability analysis during the observed modes indicates instability to n=1-3 with n=3 having the highest growth rate and unstable mode eigenfunctions peaked near the plasma edge. Discharges with Type-V and Type-I ELMs are both calculated to be on the peeling unstable side of the peeling ballooning stability curve, with the Type-V case at higher normalized pressure gradient.

  4. QUANTITATIVE TESTS OF ELMS AS INTERMEDIATE N PEELING-BALLOONING MODES

    SciTech Connect

    LAO, LL; SNYDER, PB; LEONARD, AW; OSBORNE, TH; PETRIE, TW; FERRON, JR; GROEBNER, RJ; HORTON, LD; KAMADA, Y; MURAKAMI, M; OIKAWA, T; PEARLSTEIN, LD; SAARELMA, S; STJOHN, HE; THOMAS, DM; TURNBULL, AD; WILSON, HR

    2002-07-01

    OAK A271 QUANTITATIVE TESTS OF ELMS AS INTERMEDIATE N PEELING-BALLOONING MODES. Two of the major issues crucial for the design of the next generation tokamak burning plasma devices are the predictability of the edge pedestal height and control of the divertor heat load in H-mode configurations. Both of these are strongly impacted by edge localized modes (ELMs) and their size. A working model for ELMs is that they are intermediate toroidal mode number, n {approx} 5-30, peeling-ballooning modes driven by the large edge pedestal pressure gradient P{prime} and the associated large edge bootstrap current density J{sub BS}. the interplay between P{prime} and J{sub BS} as a discharge evolves can excite peeling-ballooning modes over a wide spectrum of n. The pedestal current density plays a dual role by stabilizing the high n ballooning modes via opening access to second stability but providing free energy to drive the intermediate n peeling modes. This makes a systematic evaluation of this model particularly challenging. This paper describes recent quantitative tests of this model using experimental data from the DIII-D and the JT-60U tokamaks. These tests are made possible by recent improvements to the ELITE MHD stability code, which allow an efficient evaluation of the unstable peeling-ballooning modes, as well as by improvements to other diagnostic and analysis techniques. Some of the key testable features of this model are: (1) ELMs are triggered when the growth rates of intermediate n MHD modes become significantly large; (2) ELM sizes are related to the radial widths of the unstable modes; (3) the unstable modes have a strong ballooning character localized in the outboard bad curvature region; (4) at high collisionality, ELM size generally becomes smaller because J{sub BS} is reduced.

  5. Regulation of dimorphism in Saccharomyces cerevisiae: involvement of the novel protein kinase homolog Elm1p and protein phosphatase 2A.

    PubMed Central

    Blacketer, M J; Koehler, C M; Coats, S G; Myers, A M; Madaule, P

    1993-01-01

    The Saccharomyces cerevisiae genes ELM1, ELM2, and ELM3 were identified on the basis of the phenotype of constitutive cell elongation. Mutations in any of these genes cause a dimorphic transition to a pseudohyphal growth state characterized by formation of expanded, branched chains of elongated cells. Furthermore, elm1, elm2, and elm3 mutations cause cells to grow invasively under the surface of agar medium. S. cerevisiae is known to be a dimorphic organism that grows either as a unicellular yeast or as filamentous cells termed pseudohyphae; although the yeast-like form usually prevails, pseudohyphal growth may occur during conditions of nitrogen starvation. The morphologic and physiological properties caused by elm1, elm2, and elm3 mutations closely mimic pseudohyphal growth occurring in conditions of nitrogen starvation. Therefore, we propose that absence of ELM1, ELM2, or ELM3 function causes constitutive execution of the pseudohyphal differentiation pathway that occurs normally in conditions of nitrogen starvation. Supporting this hypothesis, heterozygosity at the ELM2 or ELM3 locus significantly stimulated the ability to form pseudohyphae in response to nitrogen starvation. ELM1 was isolated and shown to code for a novel protein kinase homolog. Gene dosage experiments also showed that pseudohyphal differentiation in response to nitrogen starvation is dependent on the product of CDC55, a putative B regulatory subunit of protein phosphatase 2A, and a synthetic phenotype was observed in elm1 cdc55 double mutants. Thus, protein phosphorylation is likely to regulate differentiation into the pseudohyphal state. Images PMID:8395007

  6. Comparative investigation of ELM control based on toroidal modelling of plasma response to RMP fields

    NASA Astrophysics Data System (ADS)

    Liu, Yueqiang

    2016-10-01

    The type-I edge localized mode (ELM), bursting at low frequency and with large amplitude, can channel a substantial amount of the plasma thermal energy into the surrounding plasma-facing components in tokamak devices operating at the high-confinement mode, potentially causing severe material damages. Learning effective ways of controlling this instability is thus an urgent issue in fusion research, in particular in view of the next generation large devices such as ITER and DEMO. Among other means, externally applied, three-dimensional resonant magnetic perturbation (RMP) fields have been experimentally demonstrated to be successful in mitigating or suppressing the type-I ELM, in multiple existing devices. In this work, we shall report results of a comparative study of ELM control using RMPs. Comparison is made between the modelled plasma response to the 3D external fields and the observed change of the ELM behaviour on multiple devices, including MAST, ASDEX Upgrade, EAST, DIII-D, JET, and KSTAR. We show that toroidal modelling of the plasma response, based on linear and quasi-linear magnetohydrodynamic (MHD) models, provides essential insights that are useful in interpreting and guiding the ELM control experiments. In particular, linear toroidal modelling results, using the MARS-F code, reveal the crucial role of the edge localized peeling-tearing mode response during ELM mitigation/suppression on all these devices. Such response often leads to strong peaking of the plasma surface displacement near the region of weak equilibrium poloidal field (e.g. the X-point), and this provides an alternative practical criterion for ELM control, as opposed to the vacuum field based Chirikov criteria. Quasi-linear modelling using MARS-Q provides quantitative interpretation of the side effects due to the ELM control coils, on the plasma toroidal momentum and particle confinements. The particular role of the momentum and particle fluxes, associated with the neoclassical toroidal

  7. Advances in the Understanding of ELM Suppression by Resonant Magnetic Perturbations (RMPs) in DIII-D and Implications for ITER

    SciTech Connect

    Nazikian, R.

    2014-09-01

    Experiments on DIII-D have expanding the operating window for RMP ELM suppression to higher q95 with dominant electron heating and fully non-inductive current drive relevant to advanced modes of ITER operation. Robust ELM suppression has also been obtained with a reduced coil set, mitigating the risk of coil failure in maintaining ELM suppression in ITER. These results significantly expand the operating space and reduce risk for obtaining RMP ELM suppression in ITER. Efforts have also been made to search for 3D cause of ELM suppression. No internal non-axisymmetric structure is detected at the top of the pedestal, indicating that the dominant effect of the RMP is to produce an n=0 transport modification of the profiles. Linear two fluid MHD simulations using M3D-C1 indicate resonant field penetration and significant magnetic stochasticity at the top of the pedestal, consistent with the absence of detectable 3D structure in that region. A profile database was developed to compare the scaling of the pedestal and global confinement with the applied 3D field strength in ELM suppressed and ELM mitigated plasmas. The EPED pedestal model accurately predicts the measured pedestal pressure at the threshold of ELM suppression, increasing confidence in theoretical projections to ITER pedestal conditions. Both the H-factor (H(sub)98y2) and thermal energy confinement time do not degrade substantially with applied RMP fields near the threshold of ELM suppression, enhancing confidence in the compatibility of ITER high performance operation with RMP ELM suppression.

  8. English Language Teaching Profile: Belgium (Dutch Speaking).

    ERIC Educational Resources Information Center

    British Council, London (England). English-Teaching Information Centre.

    This profile in outline form discusses the English language teaching situation in the Dutch-speaking and French-speaking areas of Belgium. The situation in the Dutch-speaking region, which includes Flanders and Brussels (the latter having both Dutch and French as official languages), is described in terms of the extent of English instruction…

  9. Investigation of ELM [edge localized mode] Dynamics with the Resonant Magnetic Perturbation Effects

    SciTech Connect

    Pankin, Alexei Y.; Kritz, Arnold H.

    2011-07-19

    Topics covered are: anomalous transport and E x B flow shear effects in the H-mode pedestal; RMP (resonant magnetic perturbation) effects in NSTX discharges; development of a scaling of H-mode pedestal in tokamak plasmas with type I ELMs (edge localized modes); and divertor heat load studies.

  10. Prediction of aromatase inhibitory activity using the efficient linear method (ELM)

    PubMed Central

    Shoombuatong, Watshara; Prachayasittikul, Veda; Prachayasittikul, Virapong; Nantasenamat, Chanin

    2015-01-01

    Aromatase inhibition is an effective treatment strategy for breast cancer. Currently, several in silico methods have been developed for the prediction of aromatase inhibitors (AIs) using artificial neural network (ANN) or support vector machine (SVM). In spite of this, there are ample opportunities for further improvements by developing a simple and interpretable quantitative structure-activity relationship (QSAR) method. Herein, an efficient linear method (ELM) is proposed for constructing a highly predictive QSAR model containing a spontaneous feature importance estimator. Briefly, ELM is a linear-based model with optimal parameters derived from genetic algorithm. Results showed that the simple ELM method displayed robust performance with 10-fold cross-validation MCC values of 0.64 and 0.56 for steroidal and non-steroidal AIs, respectively. Comparative analyses with other machine learning methods (i.e. ANN, SVM and decision tree) were also performed. A thorough analysis of informative molecular descriptors for both steroidal and non-steroidal AIs provided insights into the mechanism of action of compounds. Our findings suggest that the shape and polarizability of compounds may govern the inhibitory activity of both steroidal and non-steroidal types whereas the terminal primary C(sp3) functional group and electronegativity may be required for non-steroidal AIs. The R code of the ELM method is available at http://dx.doi.org/10.6084/m9.figshare.1274030. PMID:26535037

  11. Pedestal density fluctuation dynamics during the inter-ELM cycle in DIII-D

    SciTech Connect

    Yan, Z.; McKee, G. R.; Groebner, R. J.; Snyder, P. B.; Osborne, T. H.; Burrell, K. H.; Beurskens, M. N.

    2011-05-15

    Detailed 2D measurements of long-wavelength density fluctuations in the pedestal region with beam emission spectroscopy during the period between edge localized modes (ELMs) indicate two distinct bands of fluctuations propagating in opposite poloidal directions in the plasma frame: one lower frequency band (50-150 kHz) advects in the ion-diamagnetic drift direction (ion mode) and a higher frequency band (200-400 kHz) advects in the electron diamagnetic drift direction (electron mode). The ion mode amplitude is modulated with the ELM cycle: it increases rapidly after an ELM and then saturates, similar to the evolution of the pedestal electron pressure and density gradients. The electron mode, in contrast, has no significant time evolution between ELMs. The decorrelation time of the ion mode is <5 {mu}s[{tau}{sub c}(c{sub s}/c{sub s}aa){<=}1], the radial correlation length is of order 10 {rho}{sub i} and has poloidal wave-number k{sub {theta}{rho}i{approx}}0.1, and the mode advects at near the ion diamagnetic velocity in the plasma frame. These spatiotemporal dynamics are qualitatively similar to features predicted for kinetic ballooning modes.

  12. Some Guides to Discovery About Elm Trees, Owls, Cockroaches, Earthworms, Cement and Concrete.

    ERIC Educational Resources Information Center

    Busch, Phyllis S.

    The introduction emphasizes the need for environmental and conservation education, and advocates an inquiry approach. Outdoor resources available to every school are listed. Detailed suggestions are made for investigating cement and concrete, cockroaches, earthworms, elm trees, and owls. In each case general background information and a list of…

  13. VIEW FROM EAST SIDE OF ELM DRIVE/BIRCH CIRCLE BLOCK, SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW FROM EAST SIDE OF ELM DRIVE/BIRCH CIRCLE BLOCK, SHOWING SLOPING TOPOGRAPHY. VIEW FACING WEST. - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Intersection of Acacia Road and Brich Circle, Pearl City, Honolulu County, HI

  14. Microbial Decomposition of Elm and Oak Leaves in a Karst Aquifer †

    PubMed Central

    Eichem, Angela C.; Dodds, Walter K.; Tate, Cathy M.; Edler, Chris

    1993-01-01

    Dry Chinquapin oak (Quercus macrocarpa) and American elm (Ulmus americana) leaves were placed in four microcosms fed by groundwater springs to monitor changes in dry mass, ash-free dry mass, and microbial activity over a 35-day period. Oxygen microelectrodes were used to measure microbial activity and to estimate millimeter-scale heterogeneity in that activity. Oak leaves lost mass more slowly than elm leaves. Generally, there was a decrease in total dry weight over the first 14 days, after which total dry weight began to increase. However, there were consistent decreases in ash-free dry mass over the entire incubation period, suggesting that the material remaining after initial leaf decomposition trapped inorganic particles. Microbial activity was higher on elm leaves than on oak leaves, with peak activity occurring at 6 and 27 days, respectively. The level of oxygen saturation on the bottom surface of an elm leaf ranged between 0 and 75% within a 30-mm2 area. This spatial heterogeneity in O2 saturation disappeared when the water velocity increased from 0 to 6 cm s-1. Our results suggest that as leaves enter the groundwater, they decompose and provide substrate for microorganisms. The rate of decomposition depends on leaf type, small-scale variations in microbial activity, water velocity, and the length of submersion time. During the initial stages of decomposition, anoxic microzones are formed that could potentially be important to the biogeochemistry of the otherwise oxic aquifer. PMID:16349078

  15. Effect of RMP spectrum on ELM suppression and the divertor plasma in KSTAR

    NASA Astrophysics Data System (ADS)

    Ahn, Joon-Wook; Park, J.-K.; in, Y.; Loarte, A.; Kim, J.; Jeon, Y. M.; Park, G. Y.; Choe, W.; Hong, J. H.; Hong, S. H.; Lee, H. H.; Kang, C. S.; Ko, W. H.; Yoon, S. W.

    2016-10-01

    ELM suppression by n =1 and n =2 magnetic perturbations have been robustly obtained in KSTAR, and effects of various coil configurations for applied magnetic perturbations (MPs) on ELM suppression as well as divertor plasma conditions have been investigated. The 4 toroidal and 3 poloidal sectors of internal coils allow to fully scan the phase difference (Δφ) of n =1 between different rows of coils, where it is shown that ideal plasma response can either shield or amplify applied MPs, depending on Δφ , which leads respectively to the weakening and strengthening of divertor footprint striations compared to the vacuum case. On the other hand, shielding is found to be the dominant plasma response for all possible cases of n =2 configuration (Δφ =0o and 90o, and mid-plane coil only), which weakens footprint striations. Spectra of applied MPs have been varied by changing Δφ as well as modifying the ratio of coil currents between different row of coils, e.g. IU/IL, in order to find optimal conditions for ELM suppression and divertor heat and particle flux dispersal. Effects of divertor conditions in various density and impurity levels on the ELM behavior and footprint striations are also being investigated. Work supported by the U.S. DOE, contract # DE-AC05-00OR22725.

  16. Pedestal density fluctuation dynamics during the inter-ELM cycle in DIII-D a)

    NASA Astrophysics Data System (ADS)

    Yan, Z.; McKee, G. R.; Groebner, R. J.; Snyder, P. B.; Osborne, T. H.; Beurskens, M. N.; Burrell, K. H.

    2011-05-01

    Detailed 2D measurements of long-wavelength density fluctuations in the pedestal region with beam emission spectroscopy during the period between edge localized modes (ELMs) indicate two distinct bands of fluctuations propagating in opposite poloidal directions in the plasma frame: one lower frequency band (50-150 kHz) advects in the ion-diamagnetic drift direction (ion mode) and a higher frequency band (200-400 kHz) advects in the electron diamagnetic drift direction (electron mode). The ion mode amplitude is modulated with the ELM cycle: it increases rapidly after an ELM and then saturates, similar to the evolution of the pedestal electron pressure and density gradients. The electron mode, in contrast, has no significant time evolution between ELMs. The decorrelation time of the ion mode is <5 μs [τc(cs/csa a)≤1], the radial correlation length is of order 10 ρi and has poloidal wave-number kθρi~0.1, and the mode advects at near the ion diamagnetic velocity in the plasma frame. These spatiotemporal dynamics are qualitatively similar to features predicted for kinetic ballooning modes.

  17. Hybrid Couplers On The JET ICRF System: Commissioning And First Results on ELMs

    NASA Astrophysics Data System (ADS)

    Mayoral, M.-L.; Monakhov, I.; Walden, T.; Bobkov, Vl. V.; Blackman, T.; Graham, M.; Mailloux, J.; Noterdaeme, J.-M.; Nigthingale, M.; Ongena, J.

    2007-09-01

    During the 2004-2005 shutdown, hybrid 3 dB couplers were installed between the A2 ICRF antennas A and B. The goal was to free one of the generators to power the new ITER-like ICRF antenna, but also to use the coupler properties to increase the ICRF power on ELMs. Furthermore, the fast data acquisition system was upgraded in order to monitor the forward and reflected voltage amplitudes with a time resolution up to 4 μs. As expected, the first tests showed that the reflected powers during ELMs was successfully directed to the coupler dummy load instead of the generators and that a clear improvement in the averaged coupled power in the presence of the ELMs could be obtained. However, the existing levels of the VSWR protection against arcs appeared not satisfactory for ELM-tolerant operation and had to be re-assessed. Moreover, evidence of parasitic low-VSWR activity in the vacuum transmission lines was found, emphasizing the importance of developing VSWR independent arc detection systems.

  18. Hybrid Couplers On The JET ICRF System: Commissioning And First Results on ELMs

    SciTech Connect

    Mayoral, M.-L.; Monakhov, I.; Walden, T.; Blackman, T.; Graham, M.; Mailloux, J.; Nigthingale, M.; Ongena, J.

    2007-09-28

    During the 2004-2005 shutdown, hybrid 3 dB couplers were installed between the A2 ICRF antennas A and B. The goal was to free one of the generators to power the new ITER-like ICRF antenna, but also to use the coupler properties to increase the ICRF power on ELMs. Furthermore, the fast data acquisition system was upgraded in order to monitor the forward and reflected voltage amplitudes with a time resolution up to 4 {mu}s. As expected, the first tests showed that the reflected powers during ELMs was successfully directed to the coupler dummy load instead of the generators and that a clear improvement in the averaged coupled power in the presence of the ELMs could be obtained. However, the existing levels of the VSWR protection against arcs appeared not satisfactory for ELM-tolerant operation and had to be re-assessed. Moreover, evidence of parasitic low-VSWR activity in the vacuum transmission lines was found, emphasizing the importance of developing VSWR independent arc detection systems.

  19. Validation of BOUT + + ELM simulation by Comparison with ECEI Measurements in the KSTAR tokamak

    NASA Astrophysics Data System (ADS)

    Kim, Minwoo; Lee, Jaehyun; Choi, Minjun; Yun, Gunsu; Xu, X. Q.; Lee, Woochang; Park, Hyeon; Domier, C. W.; Luhmann, N. C., Jr.; Kstar Team

    2013-10-01

    Details of ELM dynamics has been measured in 2D using an electron cyclotron emission imaging (ECEI) diagnostic in the KSTAR tokamak. The observed ELM dynamics show complex evolution stages including linear growth, saturation, changes in mode number and rotation velocity, and localized crash. We studied the mode structure of the observed ELMs in the linear growth phase using 3-field BOUT + + simulations. The toroidal mode number (n) of ELMs, which was experimentally determined by an array of toroidal Mirnov coils, was fixed in the simulation. On the other hand, the pressure profile was adjusted to make the linear growth rate finite at the given n number. For direct comparison with the observed images, the simulation results were converted to synthetic ECEI images by taking into account instrumental broadening, intrinsic ECE broadening in the pedestal region, and system noises. The synthetic images were qualitatively well matched with the observations. As a next step, a simulation study in linear phase is planned for a self-consistent equilibrium including bootstrap current. Work supported by NRF Korea under contract no. 2013035905 and US DoE under contract no. DE-FG-02-99ER54531.

  20. A Possible Connection of Plasma Response to RMP ELM Suppression in DIII-D

    NASA Astrophysics Data System (ADS)

    Wingen, A.; Shafer, M. W.; Unterberg, E. A.; Hillis, D. L.; Ferraro, N. M.; Evans, T. E.; Snyder, P. B.

    2013-10-01

    A hypothesis of a possible relation between the so-called kink-response, a flux surface oscillation which is driven by amplification of non-resonant components of the resonant magnetic perturbation (RMP) spectrum, and the re-appearance of edge localized modes (ELMs) in the presence of RMPs is presented. Several DIII-D discharges with different responses show that those with stronger kink-response are closer to the peeling-ballooning stability limit and eventually cross into the unstable region, causing ELMs to re-appear. Simulations of the magnetic topology for all cases are compared. The topology consists of a kinetic equilibrium reconstruction, the RMP fields and a linear plasma response, calculated by resistive, 2-fluid MHD. It is found that the kink response is correlated to the edge current density while screening/amplification of resonant field components is related to flows. A transition from a tearing dominated edge to a kink dominated edge is demonstrated. A kink dominated discharge with intermittent ELMs is found to be marginally unstable in an ELITE simulation while ELM suppressed, tearing dominated discharges are inside the stability limit. Work supported by the US Department of Energy under DE-AC05-00OR22725, DE-FC02-04ER54698, and DE-FG02-95ER54309.

  1. Electron temperature fluctuations changes associated with ELM suppression by RMP in DIII-D

    NASA Astrophysics Data System (ADS)

    Sung, C.; Wang, G.; Rhodes, T.; Peebles, W.

    2015-11-01

    New results in this presentation show an increase in broadband electron temperature fluctuations (T~e) during ELM suppression by resonant magnetic perturbations (RMP). This measurement is obtained via correlation ECE (CECE) near the top of the pedestal (ρ ~ 0.9 - 0.96). This T~e increase is significant, (>40%), and occurs after the ELM suppression but not between ELMS. This may imply an increase in thermal transport facilitated by the increased T~e levels. Considering that the changes in gradient scale length during ELMs with RMP are complicated, it is possible that the mechanism responsible for changing T~e is different compared to previously observed changes in ñe [G. R. McKee et al NF 2013]. This possibility, and the nature of the T~e , will be studied through profile analysis and linear gyrokinetic analysis using TGLF [J. E. Kinsey et al PoP 2008]. In addition, the relation between the T~e and an observed low frequency coherent mode will be investigated. Work supported by the US DOE under DE-FG02-08ER54984 and DE-FC02-04ER54698.

  2. An Efficient Leave-One-Out Cross-Validation-Based Extreme Learning Machine (ELOO-ELM) With Minimal User Intervention.

    PubMed

    Shao, Zhifei; Er, Meng Joo; Wang, Ning

    2016-08-01

    It is well known that the architecture of the extreme learning machine (ELM) significantly affects its performance and how to determine a suitable set of hidden neurons is recognized as a key issue to some extent. The leave-one-out cross-validation (LOO-CV) is usually used to select a model with good generalization performance among potential candidates. The primary reason for using the LOO-CV is that it is unbiased and reliable as long as similar distribution exists in the training and testing data. However, the LOO-CV has rarely been implemented in practice because of its notorious slow execution speed. In this paper, an efficient LOO-CV formula and an efficient LOO-CV-based ELM (ELOO-ELM) algorithm are proposed. The proposed ELOO-ELM algorithm can achieve fast learning speed similar to the original ELM without compromising the reliability feature of the LOO-CV. Furthermore, minimal user intervention is required for the ELOO-ELM, thus it can be easily adopted by nonexperts and implemented in automation processes. Experimentation studies on benchmark datasets demonstrate that the proposed ELOO-ELM algorithm can achieve good generalization with limited user intervention while retaining the efficiency feature.

  3. Spatial Distribution and Site-Specific Spraying of Main Sucking Pests of Elm Trees.

    PubMed

    Karimzadeh, R; Iranipour, S

    2016-11-09

    Elm trees are important landscape trees and sucking insects weaken the elm trees and produce large amounts of honeydew. The main objectives of this study were to identify main honeydew-producing pests of elm trees and do site-specific spraying against these pests. To map the spatial distribution of the sucking pests in the large scale, the study area was divided into 40 × 40 m grids and one tree was chosen randomly from each grid (a total of 55 trees). These trees were sampled twice a year in 2011 and 2012. Each sample was a 30-cm branch terminal. Eight samples were taken from each tree in four cardinal directions and two canopy levels. The number of sucking insects and leaves of each sample were counted and recorded. Spatial analysis of the data was carried out using geostatistics. Kriging was used for producing prediction maps. Insecticide application was restricted to the regions with populations higher than threshold. To identify within-tree distribution of the honeydew-producing pests, six and four elm trees were chosen in 2011 and 2012 respectively, and sampled weekly. These trees were sampled as described previously. European elm scale (EES), Gossyparia spuria (Modeer) and two species of aphids were the dominant honeydew-producing pests. The results revealed that the effects of direction, canopy level and their interactions on insect populations were not statistically significant (P < 0.05). Site-specific spraying decreased the amount of insecticides used by ca. 20%, while satisfactory control of the sucking pests and honeydew excretion was obtained. Considering the environmental and economic benefits of site-specific spraying, it is worth doing more complementary works in this area.

  4. Effect of Aspect Ratio on H-mode and ELM Characteristics

    NASA Astrophysics Data System (ADS)

    Thome, K. E.; Bodner, G. M.; Bongard, M. W.; Burke, M. G.; Fonck, R. J.; Kriete, D. M.

    2015-11-01

    The H-mode confinement regime is achieved at near-unity aspect ratio (A < 1 . 2) in the Pegasus Toroidal Experiment via high-field-side fueling and low edge recycling. Ohmic H-mode is attained in both limited and diverted magnetic topologies. This regime is characterized by: reduced Dα emissions; increased core rotation; increased central heating; formation of edge current and pressure pedestals; and measured energy confinement consistent with the ITER98pb(y,2) scaling. The H-mode power threshold, PLH , behaves quite differently at low- A when compared with high- A operations. PLH /PLH_ITPA 08 increases sharply as A is lowered and no difference in PLH for limited and diverted plasmas is observed at A ~ 1 . 2 . No minimum in PLH with density is observed. Some of these results are consistent with the FM3 model for the L-H transition. Two classes of ELMs have been observed. Small, Type III-like ELMs are present at low input power and have n <= 4 . At POH >>PLH , they transition to large, Type-I-like ELMs with intermediate 5 < n < 15 . The Type III ELM magnetic structures behave opposite that of high- A plasmas, with n much higher, presumably due to the naturally higher J / B peeling mode drive at low- A . Long-sought measurements of the Jedge (R , t) pedestal collapse during an ELM event show a complex, multimodal pedestal collapse and the subsequent ejection of a current-carrying filament. Work supported by US DOE grant DE-FG02-96ER54375.

  5. Tree and stand transpiration in a Midwestern bur oak savanna after elm encroachment and restoration thinning

    USGS Publications Warehouse

    Asbjornsen, H.; Tomer, M.D.; Gomez-Cardenas, M.; Brudvig, L.A.; Greenan, C.M.; Schilling, K.

    2007-01-01

    Oak savannas, once common in the Midwest, are now isolated remnants within agricultural landscapes. Savanna remnants are frequently encroached by invasive trees to become woodlands. Thinning and prescribed burning can restore savanna structure, but the ecohydrological effects of managing these remnants are poorly understood. In this study, we measured sap flow (Js) to quantify transpiration in an Iowa bur oak (Quercus macrocarpa) savanna woodland encroached by elms (Ulmus americana), and in an adjacent restored savanna after thinning to remove elms, during summer 2004. Savanna oaks had greater mean daily Js (35.9 L dm-2 day-1) than woodland oaks (20.7 L dm-2 day-1) and elms (12.4 L dm-2 day-1). The response of Js to vapor pressure deficit (D) was unexpectedly weak, although oaks in both stands showed negative correlation between daily Js and D for D > 0.4 kPa. An earlier daily peak in Js in the elm trees showed a possible advantage for water uptake. As anticipated, the woodland's stand transpiration was greater (1.23 mm day-1) than the savanna's (0.35 mm day-1), yet the savanna achieved 30% of the woodland's transpiration with only 11% of its sapwood area. The difference in transpiration influenced water table depths, which were 2 m in the savanna and 6.5 m in the woodland. Regionally, row-crop agriculture has increased groundwater recharge and raised water tables, providing surplus water that perhaps facilitated elm encroachment. This has implications for restoration of savanna remnants. If achieving a savanna ecohydrology is an aim of restoration, then restoration strategies may require buffers, or targeting of large or hydrologically isolated remnants. ?? 2007.

  6. [Effects of aboveground and belowground competition between grass and tree on elm seedlings growth in Horqin Sandy Land].

    PubMed

    Tang, Yi; Jiang, De-ming; Chen, Zhuo; Toshio, Oshida

    2011-08-01

    Elm sparse woodland steppe plays an important role in vegetation restoration and landscape protection in Horqin Sandy Land. In this paper, a two-factor and two-level field experiment was conducted to explore the effects of aboveground and belowground competition between grass and tree on the growth of elm seedlings in the Sandy Land. Five aspects were considered, i.e., seedling biomass, belowground biomass/aboveground biomass, stem height, ratio of root to stem, and leaf number. For the one-year-old elm seedlings, their biomass showed a trend of no competition > aboveground competition > full competition > belowground competition, belowground biomass / aboveground biomass showed a trend of belowground competition > full competition > no competition > aboveground competition, stem height showed a trend of aboveground competition > no competition > full competition > belowground competition, root/stem ratio showed a trend of belowground competition > full competition > no competition > aboveground competition, and leaf number showed a trend of aboveground competition > no competition > belowground competition > full competition. Belowground competition had significant effects on the growth of one-year-old elm seedlings, while aboveground competition did not have. Neither belowground competition nor aboveground competition had significant effects on the growth of two-year-old elm seedlings. It was suggested that in Horqin Sandy Land, grass affected the growth of elm seedlings mainly via below-ground competition, but the belowground competition didn' t affect the resource allocation of elm seedlings. With the age increase of elm seedlings, the effects of grass competition on the growth of elm seedlings became weaker.

  7. Impact of Te and ne on edge current density profiles in ELM mitigated regimes on ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Dunne, M. G.; Rathgeber, S.; Burckhart, A.; Fischer, R.; Giannone, L.; McCarthy, P. J.; Schneider, P. A.; Wolfrum, E.; the ASDEX Upgrade Team

    2015-01-01

    ELM resolved edge current density profiles are reconstructed using the CLISTE equilibrium code. As input, highly spatially and temporally resolved edge electron temperature and density profiles are used in addition to data from the extensive set of external poloidal field measurements available at ASDEX Upgrade, flux loop difference measurements, and current measurements in the scrape-off layer. Both the local and flux surface averaged current density profiles are analysed for several ELM mitigation regimes. The focus throughout is on the impact of altered temperature and density profiles on the current density. In particular, many ELM mitigation regimes rely on operation at high density. Two reference plasmas with type-I ELMs are analysed, one with a deuterium gas puff and one without, in order to provide a reference for the behaviour in type-II ELMy regimes and high density ELM mitigation with external magnetic perturbations at ASDEX Upgrade. For type-II ELMs it is found that while a similar pedestal top pressure is sustained at the higher density, the temperature gradient decreases in the pedestal. This results in lower local and flux surface averaged current densities in these phases, which reduces the drive for the peeling mode. No significant differences between the current density measured in the type-I phase and ELM mitigated phase is seen when external perturbations are applied, though the pedestal top density was increased. Finally, ELMs during the nitrogen seeded phase of a high performance discharge are analysed and compared to ELMs in the reference phase. An increased pedestal pressure gradient, which is the source of confinement improvement in impurity seeded discharges, causes a local current density increase. However, the increased Zeff in the pedestal acts to reduce the flux surface averaged current density. This dichotomy, which is not observed in other mitigation regimes, could act to stabilize both the ballooning mode and the peeling mode at the

  8. Dutch museum marks Einstein anniversary

    NASA Astrophysics Data System (ADS)

    van Calmthout, Matijn

    2016-01-01

    A new painting of Albert Einstein's field equation from his 1915 general theory of relativity was unveiled in a ceremony in November 2015 by the Dutch physicist Robbert Dijkgraaf, who is director of the Princeton Institute for Advanced Study in the US.

  9. Metalinguistic Awareness in Dutch Immigrants.

    ERIC Educational Resources Information Center

    de Bot, Kees

    1992-01-01

    Data are presented on some aspects of metalinguistic awareness in Dutch adults who emigrated to Australia at least 25 years ago. The findings show that the migrants do not differ significantly from a control group in the Netherlands, suggesting that first-language metalinguistic skills are extremely resistant to attrition. (Contains nine…

  10. Genetic parameters of insect bite hypersensitivity in Dutch Friesian broodmares.

    PubMed

    Schurink, A; Ducro, B J; Heuven, H C M; van Arendonk, J A M

    2011-05-01

    Insect bite hypersensitivity (IBH) is a seasonal allergic skin disease in horses caused by bites of certain Culicoides spp. The aim of our study was to investigate the maternal effect on IBH and to estimate the heritability and repeatability of IBH in the Dutch Friesian horse population. Data consisted of 3,453 Dutch Friesian broodmares with 3,763 visual observations on IBH clinical symptoms scored by 12 inspectors during organized foal inspections in 2004 and 2008. Nine percent of the mares (n = 310) were scored in both years. Mares descended from 144 sires and 2,554 dams and 26.2% of the dams (n = 669) had more than 1 offspring in the data set (range: 2 to 6). Insect bite hypersensitivity was analyzed as a binary trait with a threshold animal model with and without a maternal effect, using a Bayesian approach. Observed IBH prevalence in Dutch Friesian broodmare population was 18.2%. Heritability on the liability scale was 0.16 (SD = 0.06); heritability on the observed scale was 0.07; and repeatability was 0.89 (SD = 0.03). Maternal effect was 0.17 (SD = 0.06) and significantly differed from zero, although the animal model without a maternal effect fitted the data better. These results show that genetic and permanent environmental factors affect IBH in Dutch Friesian horses. The dam affected the IBH development of her offspring through an additive genetic influence but also by being part of their rearing environment.

  11. Recurrent stroke after transient ischaemic attack or minor ischaemic stroke: does the distinction between small and large vessel disease remain true to type? Dutch TIA Trial Study Group.

    PubMed Central

    Kappelle, L J; van Latum, J C; van Swieten, J C; Algra, A; Koudstaal, P J; van Gijn, J

    1995-01-01

    The incidence and vascular type of recurrent ischaemic stroke was studied in patients with supratentorial transient ischaemic attacks or non-disabling ischaemic strokes, who were treated with aspirin (30 or 283 mg). Patients were divided into groups with small vessel disease (SVD) (n = 1216) or large vessel disease (LVD) (n = 1221) on the grounds of their clinical features and CT at baseline. Patients with evidence of both SVD and LVD (n = 180) were excluded from further analyses. During follow up (mean 2.6 years) annual stroke rate was 3.6% in both groups. Of the 107 patients with SVD at baseline who had recurrent strokes, 83 proved to have an identifiable infarct: 30 (28%) again had a small vessel infarct, 39 (36%) had a large vessel ischaemic stroke and in 14 (13%) the recurrent ischaemic stroke was in the posterior fossa. Of the 110 patients with LVD at baseline and recurrent stroke, 91 had an identifiable infarct: 67 (61%) again had a large vessel ischaemic stroke, 16 (15%) had a small vessel ischaemic stroke, and eight (7%) had the recurrent ischaemic stroke in the posterior fossa. Thus patients with a transient ischaemic attack or non-disabling ischaemic stroke caused by LVD were more likely to have an ischaemic stroke of the same vessel type during follow up than patients with SVD (relative risk 2.2; 95% confidence interval 1.5-3.4). Possible explanations for this difference are: (1) patients with a small vessel ischaemic stroke at baseline had both SVD and LVD or were misdiagnosed; (2) recurrent small vessel ischaemic stroke may have occurred more often than reported, because they were silent or only minimally disabling; (3) recurring large vessel ischaemic strokes occurring in patients initially diagnosed as having SVD might have been related to potential cardiac sources of emboli that had not been previously recognized; (4) the antiplatelet drug aspirin (30 or 283 mg) prescribed in this patient group may have prevented thrombosis in small vessels better

  12. Progress on the application of ELM control schemes to ITER scenarios from the non-active phase to DT operation

    NASA Astrophysics Data System (ADS)

    Loarte, A.; Huijsmans, G.; Futatani, S.; Baylor, L. R.; Evans, T. E.; Orlov, D. M.; Schmitz, O.; Becoulet, M.; Cahyna, P.; Gribov, Y.; Kavin, A.; Sashala Naik, A.; Campbell, D. J.; Casper, T.; Daly, E.; Frerichs, H.; Kischner, A.; Laengner, R.; Lisgo, S.; Pitts, R. A.; Saibene, G.; Wingen, A.

    2014-03-01

    Progress in the definition of the requirements for edge localized mode (ELM) control and the application of ELM control methods both for high fusion performance DT operation and non-active low-current operation in ITER is described. Evaluation of the power fluxes for low plasma current H-modes in ITER shows that uncontrolled ELMs will not lead to damage to the tungsten (W) divertor target, unlike for high-current H-modes in which divertor damage by uncontrolled ELMs is expected. Despite the lack of divertor damage at lower currents, ELM control is found to be required in ITER under these conditions to prevent an excessive contamination of the plasma by W, which could eventually lead to an increased disruptivity. Modelling with the non-linear MHD code JOREK of the physics processes determining the flow of energy from the confined plasma onto the plasma-facing components during ELMs at the ITER scale shows that the relative contribution of conductive and convective losses is intrinsically linked to the magnitude of the ELM energy loss. Modelling of the triggering of ELMs by pellet injection for DIII-D and ITER has identified the minimum pellet size required to trigger ELMs and, from this, the required fuel throughput for the application of this technique to ITER is evaluated and shown to be compatible with the installed fuelling and tritium re-processing capabilities in ITER. The evaluation of the capabilities of the ELM control coil system in ITER for ELM suppression is carried out (in the vacuum approximation) and found to have a factor of ˜2 margin in terms of coil current to achieve its design criterion, although such a margin could be substantially reduced when plasma shielding effects are taken into account. The consequences for the spatial distribution of the power fluxes at the divertor of ELM control by three-dimensional (3D) fields are evaluated and found to lead to substantial toroidal asymmetries in zones of the divertor target away from the separatrix

  13. Recent progress in understanding the processes underlying the triggering of and energy loss associated with type I ELMs

    NASA Astrophysics Data System (ADS)

    Kirk, A.; Dunai, D.; Dunne, M.; Huijsmans, G.; Pamela, S.; Becoulet, M.; Harrison, J. R.; Hillesheim, J.; Roach, C.; Saarelma, S.

    2014-11-01

    The type I ELMy H-mode is the baseline operating scenario for ITER. While it is known that the type I edge-localized mode (ELM) ultimately results from the peeling-ballooning instability, there is growing experimental evidence that a mode grows up before the ELM crash that may modify the edge plasma, which then leads to the ELM event due to the peeling-ballooning mode. The triggered mode results in the release of a large number of particles and energy from the core plasma but the precise mechanism by which these losses occur is still not fully understood and hence makes predictions for future devices uncertain. Recent progress in understanding the processes that trigger type I ELMs and the size of the resultant energy loss are reviewed and compared to experimental data and ideas for further development are discussed.

  14. Scrape-off layer ion temperature measurements at the divertor target during type III and type I ELMs in MAST measured by RFEA

    NASA Astrophysics Data System (ADS)

    Elmore, S.; Allan, S. Y.; Fishpool, G.; Kirk, A.; Thornton, A. J.; Walkden, N. R.; Harrison, J. R.; the MAST Team

    2016-06-01

    In future nuclear fusion reactors high heat load events, such as edge-localised modes (ELMs), can potentially damage divertor materials and release impurities into the main plasma, limiting plasma performance. The most difficult to handle are type I ELMs since they carry the largest fraction of energy from the plasma and therefore deposit the largest heat flux at the target and on first wall materials. Knowing the temperature of the ions released from ELM events is important since it determines the potential sputtering they would cause from plasma facing materials. To make measurements of T i by retarding field energy analyser (RFEA) during type I ELMs a new operational technique has been used to allow faster measurements to be made; this is called the fast swept technique (FST). The FST method allows measurements to be made within the time of the ELM event which has previously not been possible with T i measurements. This new technique has been validated by comparing it with a slower average measurement previously used to make ion temperature measurements of ELMs. Presented here are the first T i measurements during Type I ELMs made at a tokamak divertor. Temperatures as high as 20 eV are measured more than 15 cm from the peak heat flux of an ELM, in a region where no inter-ELM current is measured by the RFEA; showing that ELM events cause hot ions to reach the divertor target far into the scrape off layer. Fast camera imaging has been used to investigate the type of ELM filaments that have been measured by the divertor RFEA. It is postulated that most of the ion temperatures measured in type I ELMs are from secondary ELM filaments which have not been previously identified in MAST plasmas.

  15. ELM - A SIMPLE TOOL FOR THERMAL-HYDRAULIC ANALYSIS OF SOLID-CORE NUCLEAR ROCKET FUEL ELEMENTS

    NASA Technical Reports Server (NTRS)

    Walton, J. T.

    1994-01-01

    ELM is a simple computational tool for modeling the steady-state thermal-hydraulics of propellant flow through fuel element coolant channels in nuclear thermal rockets. Written for the nuclear propulsion project of the Space Exploration Initiative, ELM evaluates the various heat transfer coefficient and friction factor correlations available for turbulent pipe flow with heat addition. In the past, these correlations were found in different reactor analysis codes, but now comparisons are possible within one program. The logic of ELM is based on the one-dimensional conservation of energy in combination with Newton's Law of Cooling to determine the bulk flow temperature and the wall temperature across a control volume. Since the control volume is an incremental length of tube, the corresponding pressure drop is determined by application of the Law of Conservation of Momentum. The size, speed, and accuracy of ELM make it a simple tool for use in fuel element parametric studies. ELM is a machine independent program written in FORTRAN 77. It has been successfully compiled on an IBM PC compatible running MS-DOS using Lahey FORTRAN 77, a DEC VAX series computer running VMS, and a Sun4 series computer running SunOS UNIX. ELM requires 565K of RAM under SunOS 4.1, 360K of RAM under VMS 5.4, and 406K of RAM under MS-DOS. Because this program is machine independent, no executable is provided on the distribution media. The standard distribution medium for ELM is one 5.25 inch 360K MS-DOS format diskette. ELM was developed in 1991. DEC, VAX, and VMS are trademarks of Digital Equipment Corporation. Sun4 and SunOS are trademarks of Sun Microsystems, Inc. IBM PC is a registered trademark of International Business Machines. MS-DOS is a registered trademark of Microsoft Corporation.

  16. Comparison study between the observed ELM dynamics in the KSTAR H-mode and simulation results from BOUT++

    NASA Astrophysics Data System (ADS)

    Kim, Minwoo; Xu, Xueqiao; Yun, Gunsu S.; Lee, Jaehyun; Park, Hyeon K.

    2012-10-01

    The BOUT++ simulations [1] of edge localized modes (ELMs) have been quantitatively compared with high resolution 2D images of ELMs observed in typical KSTAR H-mode plasmas through an electron cyclotron emission imaging (ECEI) system [2]. The poloidal structure of the most unstable mode predicted by the linear 3-field simulation qualitatively matches with the observed ELM structure. As the next step, simulation studies for the nonlinear aspects of the ELM dynamics are planned; in particular, the transient mode structure change prior to the ELM crash [2] will be investigated. In addition, the parametric dependence of the observed ELM suppression/mitigation process during resonant magnetic perturbation (RMP) [2, 3] and supersonic molecular beam injection (SMBI) experiments will be studied using 5-field BOUT++ simulation.[4pt] [1] X.Q. Xu et al., PRL, 105 (2010).[0pt] [2] G.S. Yun et al., Phys. Plasmas, 19 (2012).[0pt] [3] Y.M. Jeon et al., accepted for publication in PRL.

  17. Comparative ELM study between the observation by ECEI and linear/nonlinear simulation in the KSTAR plasmas

    NASA Astrophysics Data System (ADS)

    Kim, Minwoo; Park, Hyeon K.; Yun, Gunsu; Lee, Jaehyun; Lee, Jieun; Lee, Woochang; Jardin, Stephen; Xu, X. Q.; Kstar Team

    2015-11-01

    The modeling of the Edge-localized-mode (ELM) should be rigorously pursued for reliable and robust ELM control for steady-state long-pulse H-mode operation in ITER as well as DEMO. In the KSTAR discharge #7328, a linear stability of the ELMs is investigated using M3D-C1 and BOUT + + codes. This is achieved by linear simulation for the n = 8 mode structure of the ELM observed by the KSTAR electron cyclotron emission imaging (ECEI) systems. In the process of analysis, variations due to the plasma equilibrium profiles and transport coefficients on the ELM growth rate are investigated and simulation results with the two codes are compared. The numerical simulations are extended to nonlinear phase of the ELM dynamics, which includes saturation and crash of the modes. Preliminary results of the nonlinear simulations are compared with the measured images especially from the saturation to the crash. This work is supported by NRF of Korea under contract no. NRF-2014M1A7A1A03029865, US DoE by LLNL under contract DE-AC52-07NA27344 and US DoE by PPPL under contract DE-AC02-09CH11466.

  18. Fault Diagnosis for Analog Circuits by Using EEMD, Relative Entropy, and ELM.

    PubMed

    Xiong, Jian; Tian, Shulin; Yang, Chenglin

    2016-01-01

    This paper presents a novel fault diagnosis method for analog circuits using ensemble empirical mode decomposition (EEMD), relative entropy, and extreme learning machine (ELM). First, nominal and faulty response waveforms of a circuit are measured, respectively, and then are decomposed into intrinsic mode functions (IMFs) with the EEMD method. Second, through comparing the nominal IMFs with the faulty IMFs, kurtosis and relative entropy are calculated for each IMF. Next, a feature vector is obtained for each faulty circuit. Finally, an ELM classifier is trained with these feature vectors for fault diagnosis. Via validating with two benchmark circuits, results show that the proposed method is applicable for analog fault diagnosis with acceptable levels of accuracy and time cost.

  19. Fault Diagnosis for Analog Circuits by Using EEMD, Relative Entropy, and ELM

    PubMed Central

    Tian, Shulin

    2016-01-01

    This paper presents a novel fault diagnosis method for analog circuits using ensemble empirical mode decomposition (EEMD), relative entropy, and extreme learning machine (ELM). First, nominal and faulty response waveforms of a circuit are measured, respectively, and then are decomposed into intrinsic mode functions (IMFs) with the EEMD method. Second, through comparing the nominal IMFs with the faulty IMFs, kurtosis and relative entropy are calculated for each IMF. Next, a feature vector is obtained for each faulty circuit. Finally, an ELM classifier is trained with these feature vectors for fault diagnosis. Via validating with two benchmark circuits, results show that the proposed method is applicable for analog fault diagnosis with acceptable levels of accuracy and time cost. PMID:27698663

  20. Variation in the prion protein sequence in Dutch goat breeds.

    PubMed

    Windig, J J; Hoving, R A H; Priem, J; Bossers, A; van Keulen, L J M; Langeveld, J P M

    2016-10-01

    Scrapie is a neurodegenerative disease occurring in goats and sheep. Several haplotypes of the prion protein increase resistance to scrapie infection and may be used in selective breeding to help eradicate scrapie. In this study, frequencies of the allelic variants of the PrP gene are determined for six goat breeds in the Netherlands. Overall frequencies in Dutch goats were determined from 768 brain tissue samples in 2005, 766 in 2008 and 300 in 2012, derived from random sampling for the national scrapie surveillance without knowledge of the breed. Breed specific frequencies were determined in the winter 2013/2014 by sampling 300 breeding animals from the main breeders of the different breeds. Detailed analysis of the scrapie-resistant K222 haplotype was carried out in 2014 for 220 Dutch Toggenburger goats and in 2015 for 942 goats from the Saanen derived White Goat breed. Nine haplotypes were identified in the Dutch breeds. Frequencies for non-wild type haplotypes were generally low. Exception was the K222 haplotype in the Dutch Toggenburger (29%) and the S146 haplotype in the Nubian and Boer breeds (respectively 7 and 31%). The frequency of the K222 haplotype in the Toggenburger was higher than for any other breed reported in literature, while for the White Goat breed it was with 3.1% similar to frequencies of other Saanen or Saanen derived breeds. Further evidence was found for the existence of two M142 haplotypes, M142 /S240 and M142 /P240 . Breeds vary in haplotype frequencies but frequencies of resistant genotypes are generally low and consequently selective breeding for scrapie resistance can only be slow but will benefit from animals identified in this study. The unexpectedly high frequency of the K222 haplotype in the Dutch Toggenburger underlines the need for conservation of rare breeds in order to conserve genetic diversity rare or absent in other breeds.

  1. Neonicotinoid Insecticide Imidacloprid Causes Outbreaks of Spider Mites on Elm Trees in Urban Landscapes

    PubMed Central

    Szczepaniec, Adrianna; Creary, Scott F.; Laskowski, Kate L.; Nyrop, Jan P.; Raupp, Michael J.

    2011-01-01

    Background Attempts to eradicate alien arthropods often require pesticide applications. An effort to remove an alien beetle from Central Park in New York City, USA, resulted in widespread treatments of trees with the neonicotinoid insecticide imidacloprid. Imidacloprid's systemic activity and mode of entry via roots or trunk injections reduce risk of environmental contamination and limit exposure of non-target organisms to pesticide residues. However, unexpected outbreaks of a formerly innocuous herbivore, Tetranychus schoenei (Acari: Tetranychidae), followed imidacloprid applications to elms in Central Park. This undesirable outcome necessitated an assessment of imidacloprid's impact on communities of arthropods, its effects on predators, and enhancement of the performance of T. schoenei. Methodology/Principal Findings By sampling arthropods in elm canopies over three years in two locations, we document changes in the structure of communities following applications of imidacloprid. Differences in community structure were mostly attributable to increases in the abundance of T. schoenei on elms treated with imidacloprid. In laboratory experiments, predators of T. schoenei were poisoned through ingestion of prey exposed to imidacloprid. Imidacloprid's proclivity to elevate fecundity of T. schoenei also contributed to their elevated densities on treated elms. Conclusions/Significance This is the first study to report the effects of pesticide applications on the arthropod communities in urban landscapes and demonstrate that imidacloprid increases spider mite fecundity through a plant-mediated mechanism. Laboratory experiments provide evidence that imidacloprid debilitates insect predators of spider mites suggesting that relaxation of top-down regulation combined with enhanced reproduction promoted a non-target herbivore to pest status. With global commerce accelerating the incidence of arthropod invasions, prophylactic applications of pesticides play a major role in

  2. External kink modes as a model for MHD activity associated with ELMs

    SciTech Connect

    Manickam, J.

    1992-01-01

    Tokamak plasmas in the high confinement mode of operation are known to exhibit edge localized activity referred to as ELMs. A model is proposed for the underlying cause in terms of the external kink mode. The build up of the current density near the plasma edge is shown to decrease the shear in the safety-factor, q, profile and lead to destabilization of the kink mode. The role of the plasma geometry and equilibrium profiles is discussed.

  3. PROGRESS IN THE PEELING-BALLOONING MODEL OF ELMS: TOROIDAL ROTATION AND 3D NONLINEAR DYNAMICS

    SciTech Connect

    SNYDER,P.B; WILSON,H.R; XU,X.Q; WEBSTER,A.J

    2004-06-01

    Understanding the physics of the H-Mode pedestal and edge localized modes (ELMs) is very important to next-step fusion devices for two primary reasons: (1) The pressure at the top of the edge barrier (''pedestal height'') strongly impacts global confinement and fusion performance, and (2) large ELMs lead to localized transient heat loads on material surfaces that may constrain component lifetimes. The development of the peeling-ballooning model has shed light on these issues by positing a mechanism for ELM onset and constraints on the pedestal height. The mechanism involves instability of ideal coupled ''peeling-ballooning'' modes driven by the sharp pressure gradient and consequent large bootstrap current in the H-mode edge. It was first investigated in the local, high-n limit [1], and later quantified for non-local, finite-n modes in general toroidal geometry [2,3]. Important aspects are that a range of wavelengths may potentially be unstable, with intermediate n's (n {approx} 3-30) generally limiting in high performance regimes, and that stability bounds are strongly sensitive to shape [Fig l(a)], and to collisionality (i.e. temperature and density) [4] through the bootstrap current. The development of efficient MHD stability codes such as ELITE [3,2] and MISHKA [5] has allowed detailed quantification of peeling-ballooning stability bounds (e.g. [6]) and extensive and largely successful comparisons with observation (e.g. [2,6-9]). These previous calculations are ideal, static, and linear. Here we extend this work to incorporate the impact of sheared toroidal rotation, and the non-ideal, nonlinear dynamics which must be studied to quantify ELM size and heat deposition on material surfaces.

  4. The Rock Elm meteorite impact structure, Wisconsin: Geology and shock-metamorphic effects in quartz

    USGS Publications Warehouse

    French, B.M.; Cordua, W.S.; Plescia, J.B.

    2004-01-01

    The Rock Elm structure in southwest Wisconsin is an anomalous circular area of highly deformed rocks, ???6.5 km in diameter, located in a region of virtually horizontal undeformed sedimentary rocks. Shock-produced planar microstructures (PMs) have been identified in quartz grains in several lithologies associated with the structure: sandstones, quartzite pebbles, and breccia. Two distinct types of PMs are present: P1 features, which appear identical to planar fractures (PFs or cleavage), and P2 features, which are interpreted as possible incipient planar deformation features (PDFs). The latter are uniquely produced by the shock waves associated with meteorite impact events. Both types of PMs are oriented parallel to specific crystallographic planes in the quartz, most commonly to c(0001), ??112??2, and r/z101??1. The association of unusual, structurally deformed strata with distinct shock-produced microdeformation features in their quartz-bearing rocks establishes Rock Elm as a meteorite impact structure and supports the view that the presence of multiple parallel cleavages in quartz may be used independently as a criterion for meteorite impact. Preliminary paleontological studies indicate a minimum age of Middle Ordovician for the Rock Elm structure. A similar age estimate (450-400 Ma) is obtained independently by combining the results of studies of the general morphology of complex impact structures with estimated rates of sedimentation for the region. Such methods may be applicable to dating other old and deeply eroded impact structures formed in sedimentary target rocks.

  5. Power Law Regression Analysis of Heat Flux Width in Type I ELMs

    NASA Astrophysics Data System (ADS)

    Stephens, C. D.; Makowski, M. A.; Leonard, A. W.; Osborne, T. H.

    2014-10-01

    In this project, a database of Type I ELM characteristics has been assembled and will be used to investigate possible dependencies of the heat flux width on physics and engineering parameters. At the edge near the divertor, high impulsive heat loads are imparted onto the surface. The impact of these ELMs can cause a reduction in divertor lifetime if the heat flux is great enough due to material erosion. A program will be used to analyze data, extract relevant, measurable quantities, and record the quantities in the table. Care is taken to accurately capture the complex space/time structure of the ELM. Then correlations between discharge and equilibrium parameters will be investigated. Power law regression analysis will be used to help determine the dependence of the heat flux width on these various measurable quantities and parameters. This will enable us to better understand the physics of heat flux at the edge. Work supported in part by the National Undergraduate Fellowship Program in Plasma Physics and Fusion Energy Sciences and the US DOE under DE-FG02-04ER54761, DE-AC52-07NA27344, DE-FC02-04ER54698.

  6. The Calibration of High-Speed Camera Imaging System for ELMs Observation on EAST Tokamak

    NASA Astrophysics Data System (ADS)

    Fu, Chao; Zhong, Fangchuan; Hu, Liqun; Yang, Jianhua; Yang, Zhendong; Gan, Kaifu; Zhang, Bin; East Team

    2016-09-01

    A tangential fast visible camera has been set up in EAST tokamak for the study of edge MHD instabilities such as ELM. To determine the 3-D information from CCD images, Tsai's two-stage technique was utilized to calibrate the high-speed camera imaging system for ELM study. By applying tiles of the passive stabilizers in the tokamak device as the calibration pattern, transformation parameters for transforming from a 3-D world coordinate system to a 2-D image coordinate system were obtained, including the rotation matrix, the translation vector, the focal length and the lens distortion. The calibration errors were estimated and the results indicate the reliability of the method used for the camera imaging system. Through the calibration, some information about ELM filaments, such as positions and velocities were obtained from images of H-mode CCD videos. supported by National Natural Science Foundation of China (No. 11275047), the National Magnetic Confinement Fusion Science Program of China (No. 2013GB102000)

  7. Characteristics of the TFTR limiter H-mode: The transition, ELMs, transport and confinement

    SciTech Connect

    Bush, C.E. ); Bretz, N.; Nazikian, R.; Stratton, B.C.; Synakowski, E.; Taylor, G. Budny, R.; Ramsey, A.T.; Scott, S.D.; Bell, M.; Bell, R.; Biglari, H.; Bitter, M.; Darrow, D.S.; Efthimion, P.; Fredrickson, E.D.; Hill, K.; Hsuan, H.; Kilpatrick, S.; McGuire, K.M.; Manos, D.; Mansfield, D.; Medley, S.S.; Mueller, D.; Park, H.; Paul, S.; Sabbagh, S.; Schivell, J.; Thompson, M.; Town

    1992-11-01

    H-Modes obtained through transitions from the supershot regime have been studied on TFTR. The characteristics of these H-modes are similar to those found on other tokamaks with one main exception, the density prof:des can be highly peaked. In the best cases the enhanced confinement in the core of the initial supershot is retained in the H-mode phase, while the confinement in a broad edge region is enhanced. Thus in TFTR, all of the important physics of H-modes such as transitions, enhanced edge confinement, ELMs and other phenomena are studied in a large circular limiter tokamak with the added feature of centrally peaked density profiles and the advantage of an extensive set of diagnostics. The threshold power for the transition is found to be a linear function of plasma current. Transitions and ELMs are affected by the mix of co-and counter-neutral beam injection (NBI) and by perturbations introduced by pellet injection, gas puffing, and current ramping before and during NBI. Fluctuations near both transition and ELM events have been characterized. High frequency magnetic fluctuations in the range [ge] 100--250 kHz usually decrease during the transition. Microwave scattering spectra of density fluctuations in the plasma edge show a feature at high frequency during the H-mode, which is not observed in the plasma core and which is consistent with an edge poloidal rotation velocity, V[sub [theta

  8. Toroidal drift modes in tokamaks: a new model for small ELMs

    NASA Astrophysics Data System (ADS)

    Bokshi, Arkaprava; Dickinson, David; Wilson, Howard

    2014-10-01

    Toroidal drift instabilities, such as the ion-temperature gradient (ITG) mode, are likely drivers of turbulent transport in tokamaks. Depending on the radial drive profile, two distinct mode structures can emerge: for a peaked profile, the violent Isolated Mode (IM) exists on the outboard-midplane, whereas for a linear profile, the more benign General Mode (GM) sits at the top/bottom of the plasma. The IM only exists in special conditions, so we expect the GM to usually drive turbulence. A new global code, based on an electrostatic gyrokinetic toroidal ITG model, has been developed and benchmarked to study the time-evolution of these linear modes. While we consider the ITG mode, the results are expected to be valid for most microinstabilities. A key result is that as the flow-shear evolves through a critical value, the GM evolves into the IM and then back to the GM. Curiously, the mode structure transiently passes through the violent IM phase independent of how fast the equilibrium evolves! For a pedestal evolving between ELMs, if a GM-IM-GM transition occurs, the burst in linear growth during the IM phase could drive a small ELM. The associated transport would maintain the pedestal pressure gradient below the peeling-ballooning limit, avoiding Type I ELMs.

  9. Lithium granule ablation and penetration during ELM pacing experiments at DIII-D

    SciTech Connect

    Lunsford, R.; Bortolon, A.; Roquemore, A. L.; Mansfield, D. K.; Nagy, A.; Maingi, R.; Parks, P. B.; Jackson, G.; Gilson, E.; Chrobak, C. P.

    2016-05-25

    At DIII-D, lithium granules were radially injected into the plasma at the outer midplane to trigger and pace edge localized modes (ELMs). Granules ranging in size from 300 to 1000 microns were horizontally launched into H-mode discharges with velocities near 100 m/s, and granule to granule injection frequencies less than 500 Hz. While the smaller granules were only successful in triggering ELMs approximately 20% of the time, the larger granules regularly demonstrated ELM triggering efficiencies of greater than 80%. A fast visible camera looking along the axis of injection observed the ablation of the lithium granules. We used the duration of ablation as a benchmark for a neutral gas shielding calculation, and approximated the ablation rate and mass deposition location for the various size granules, using measured edge plasma profiles as inputs. In conclusion, this calculation suggests that the low triggering efficiency of the smaller granules is due to the inability of these granules to traverse the steep edge pressure gradient region and reach the top of the pedestal prior to full ablation.

  10. Lithium granule ablation and penetration during ELM pacing experiments at DIII-D

    DOE PAGES

    Lunsford, R.; Bortolon, A.; Roquemore, A. L.; ...

    2016-05-25

    At DIII-D, lithium granules were radially injected into the plasma at the outer midplane to trigger and pace edge localized modes (ELMs). Granules ranging in size from 300 to 1000 microns were horizontally launched into H-mode discharges with velocities near 100 m/s, and granule to granule injection frequencies less than 500 Hz. While the smaller granules were only successful in triggering ELMs approximately 20% of the time, the larger granules regularly demonstrated ELM triggering efficiencies of greater than 80%. A fast visible camera looking along the axis of injection observed the ablation of the lithium granules. We used the durationmore » of ablation as a benchmark for a neutral gas shielding calculation, and approximated the ablation rate and mass deposition location for the various size granules, using measured edge plasma profiles as inputs. In conclusion, this calculation suggests that the low triggering efficiency of the smaller granules is due to the inability of these granules to traverse the steep edge pressure gradient region and reach the top of the pedestal prior to full ablation.« less

  11. Impact of impurity seeding and divertor conditions on transitions, pedestal structure and ELMs

    NASA Astrophysics Data System (ADS)

    Dunne, M. G.

    2017-02-01

    Future devices will require a high scrape-off later (SOL) density and impurity seeding to avoid high-Z sputtering. However, these operational parameters are not included in present-day scaling laws, making extrapolations to larger devices difficult. As such, understanding the physics of such effects is vital in order to design the operational scenarios most favorable to high fusion gain. This review presents the favorable lowering of L-H transition power by changing to metal walled devices and sumarises the effects currently thought to be responsible for how SOL geometry can play a role in determining this threshold. Experimental observations on changes to the pedestal structure with main ion fuelling and low-, medium-, and high-Z impurity seeding are presented. These results, from several devices, show that main ion fuelling or high density operation can result in a lower pedestal top pressure, and hence reduced stored energy, while impurity seeding can recover this lost pressure. Particular focus is given to nitrogen seeded discharges and the recovery of pedestal parameters (notably high {{T}\\text{e,\\text{ped}}} ) in JET and AUG since the changeover to metal walls in these devices. Lithium seeding is also emerging as a strong actuator in pedestal dynamics, with results ranging from a prolonged inter-ELM period to completely ELM-free scenarios on different devices. ELM dynamics are also presented in each section, with nitrogen seeding offering a probe into the structure of the ELM and demonstrating the difference between the initial ELM crash, likely due to a sharp MHD event, and a prolonged second phase, the origin of which remains unkown. Finally, modelling of the pedestal in impurity seeded scenarios reveals a common effect in the position of the density profile. Either through mode excitation near to the separatrix or an altered fuelling profile, seeding of impurities results in an inward shift of the density profile. This inward shift improves MHD stability

  12. Intermediate-k density and magnetic field fluctuations during inter-ELM pedestal evolution in MAST

    NASA Astrophysics Data System (ADS)

    Hillesheim, J. C.; Dickinson, D.; Roach, C. M.; Saarelma, S.; Scannell, R.; Kirk, A.; Crocker, N. A.; Peebles, W. A.; Meyer, H.; the MAST Team

    2016-01-01

    Measurements of local density and magnetic field fluctuations near the pedestal top, conditionally averaged over the edge localized mode (ELM) cycle, have been made in Mega Amp Spherical Tokamak (MAST). A Doppler backscattering (DBS) system installed at MAST was used to measure intermediate-k ≤ft({{k}\\bot}{ρi}≈ 3~\\text{to}~4\\right) density fluctuations at the top of the pedestal. A novel diagnostic technique combining DBS with cross-polarization scattering (CP-DBS) enabled magnetic field fluctuations to also be locally measured at similar wave numbers. Polarization isolation and other effects for CP-DBS are discussed. Both measurements were used in a series of high-β ≤ft({βn}≈ 4.0\\right. -4.5) MAST plasmas with large type-I ELMs with an ˜ 8~\\text{to}~9~\\text{ms} period where microtearing modes (MTMs) had been predicted to be unstable in similar conditions (Dickinson 2012 Phys. Rev. Lett. 108 135002). The measured density fluctuation level increased by a factor of about 4 between 2 and 4 ms after the ELM, which was correlated with the recovery of the density profile while the temperature pedestal height continued to increase slowly. Magnetic field fluctuations showed different temporal behaviors, slowly increasing throughout the ELM cycle as the local β increased. Linear GS2 calculations show both MTM and electron temperature gradient (ETG) modes unstable at similar wave numbers as the measurements (although with more overlap between ETG wave numbers and diagnostic spectral resolution) at the top of the pedestal, along with kinetic ballooning modes are unstable lower in the pedestal (at larger wavelengths). The inferred ratio of fluctuation levels from experiment was ≤ft(δ B/B\\right)/≤ft(δ n/n\\right)≈ 1/20 . The comparable ratios from GS2 were ≤ft(δ B/B\\right)/≤ft(δ n/n\\right)≈ 0.4 for the MTM and ≤ft(δ B/B\\right)/≤ft(δ n/n\\right)≈ 0.02 for the ETG. Both the experimental wave number range and the fluctuation ratio

  13. An Expert Diagnosis System for Parkinson Disease Based on Genetic Algorithm-Wavelet Kernel-Extreme Learning Machine.

    PubMed

    Avci, Derya; Dogantekin, Akif

    2016-01-01

    Parkinson disease is a major public health problem all around the world. This paper proposes an expert disease diagnosis system for Parkinson disease based on genetic algorithm- (GA-) wavelet kernel- (WK-) Extreme Learning Machines (ELM). The classifier used in this paper is single layer neural network (SLNN) and it is trained by the ELM learning method. The Parkinson disease datasets are obtained from the UCI machine learning database. In wavelet kernel-Extreme Learning Machine (WK-ELM) structure, there are three adjustable parameters of wavelet kernel. These parameters and the numbers of hidden neurons play a major role in the performance of ELM. In this study, the optimum values of these parameters and the numbers of hidden neurons of ELM were obtained by using a genetic algorithm (GA). The performance of the proposed GA-WK-ELM method is evaluated using statical methods such as classification accuracy, sensitivity and specificity analysis, and ROC curves. The calculated highest classification accuracy of the proposed GA-WK-ELM method is found as 96.81%.

  14. Experimental estimation of tungsten impurity sputtering due to Type I ELMs in JET-ITER-like wall using pedestal electron cyclotron emission and target Langmuir probe measurements

    NASA Astrophysics Data System (ADS)

    Guillemaut, C.; Jardin, A.; Horacek, J.; Borodkina, I.; Autricque, A.; Arnoux, G.; Boom, J.; Brezinsek, S.; Coenen, J. W.; De La Luna, E.; Devaux, S.; Eich, T.; Harting, D.; Kirschner, A.; Lipschultz, B.; Matthews, G. F.; Meigs, A.; Moulton, D.; O'Mullane, M.; Stamp, M.; contributors, JET

    2016-02-01

    The ITER baseline scenario, with 500 MW of DT fusion power and Q = 10, will rely on a Type I ELMy H-mode and will be achieved with a tungsten (W) divertor. W atoms sputtered from divertor targets during mitigated ELMs are expected to be the dominant source in ITER. W impurity concentration in the plasma core can dramatically degrade its performance and lead to potentially damaging disruptions. Understanding the physics of the target W source due to sputtering during ELMs and inter-ELMs is important and can be helped by experimental measurements with improved precision. It has been established that the ELMy target ion impact energy has a simple linear dependence with the pedestal electron temperature measured by Electron Cyclotron Emission (ECE). It has also been shown that Langmuir Probes (LP) ion flux measurements are reliable during ELMs due to the surprisingly low electron temperature. Therefore, in this paper, LP and ECE measurements in JET-ITER-Like-Wall (ILW) unseeded Type I ELMy H-mode experiments have been used to estimate the W sputtering flux from divertor targets in ELM and inter-ELM conditions. Comparison with similar estimates using W I spectroscopy measurements shows a reasonable agreement for the ELM and inter-ELM W source. The main advantage of the method involving LP measurements is the very high time resolution of the diagnostic (˜10 μs) allowing very precise description of the W sputtering source during ELMs.

  15. Connection between plasma response and resonant magnetic perturbation (RMP) edge localized mode (ELM) suppression in DIII-D

    SciTech Connect

    Wingen, Andreas; Ferraro, N. M.; Shafer, Morgan W.; Unterberg, Ezekial A.; Canik, John M.; Evans, T. E.; Hillis, Donald Lee; Hirshman, Steven Paul; Seal, Sudip K.; Snyder, P. B.; Sontag, Aaron C.

    2015-09-03

    Calculations of the plasma response to applied non-axisymmetric fields in several DIII-D discharges show that predicted displacements depend strongly on the edge current density. This result is found using both a linear two-fluid-MHD model (M3D-C1) and a nonlinear ideal-MHD model (VMEC). Furthermore, it is observed that the probability of a discharge being edge localized mode (ELM)-suppressed is most closely related to the edge current density, as opposed to the pressure gradient. It is found that discharges with a stronger kink response are closer to the peeling–ballooning stability limit in ELITE simulations and eventually cross into the unstable region, causing ELMs to reappear. Thus for effective ELM suppression, the RMP has to prevent the plasma from generating a large kink response, associated with ELM instability. Experimental observations are in agreement with the finding; discharges which have a strong kink response in the MHD simulations show ELMs or ELM mitigation during the RMP phase of the experiment, while discharges with a small kink response in the MHD simulations are fully ELM suppressed in the experiment by the applied resonant magnetic perturbation. The results are cross-checked against modeled 3D ideal MHD equilibria using the VMEC code. The procedure of constructing optimal 3D equilibria for diverted H-mode discharges using VMEC is presented. As a result, kink displacements in VMEC are found to scale with the edge current density, similar to M3D-C1, but the displacements are smaller. A direct correlation in the flux surface displacements to the bootstrap current is shown.

  16. Connection between plasma response and resonant magnetic perturbation (RMP) edge localized mode (ELM) suppression in DIII-D

    NASA Astrophysics Data System (ADS)

    Wingen, A.; Ferraro, N. M.; Shafer, M. W.; Unterberg, E. A.; Canik, J. M.; Evans, T. E.; Hillis, D. L.; Hirshman, S. P.; Seal, S. K.; Snyder, P. B.; Sontag, A. C.

    2015-10-01

    Calculations of the plasma response to applied non-axisymmetric fields in several DIII-D discharges show that predicted displacements depend strongly on the edge current density. This result is found using both a linear two-fluid-MHD model (M3D-C1) and a nonlinear ideal-MHD model (VMEC). Furthermore, it is observed that the probability of a discharge being edge localized mode (ELM)-suppressed is most closely related to the edge current density, as opposed to the pressure gradient. It is found that discharges with a stronger kink response are closer to the peeling-ballooning stability limit in ELITE simulations and eventually cross into the unstable region, causing ELMs to reappear. Thus for effective ELM suppression, the RMP has to prevent the plasma from generating a large kink response, associated with ELM instability. Experimental observations are in agreement with the finding; discharges which have a strong kink response in the MHD simulations show ELMs or ELM mitigation during the RMP phase of the experiment, while discharges with a small kink response in the MHD simulations are fully ELM suppressed in the experiment by the applied resonant magnetic perturbation. The results are cross-checked against modeled 3D ideal MHD equilibria using the VMEC code. The procedure of constructing optimal 3D equilibria for diverted H-mode discharges using VMEC is presented. Kink displacements in VMEC are found to scale with the edge current density, similar to M3D-C1, but the displacements are smaller. A direct correlation in the flux surface displacements to the bootstrap current is shown.

  17. Value Orientations of the Dutch Educational Elite.

    ERIC Educational Resources Information Center

    Karsten, Sjoerd; And Others

    1995-01-01

    Value orientations that influence opinions on educational policy issues were examined among Dutch leaders of educationally influential organizations. Their attitudes reflected Dutch society's segmentation along, but cooperation across, religious and ideological dividing lines, as well as optimism about educational reform through state…

  18. [Dutch parliament legitimizes harmful quackery].

    PubMed

    van Dam, Frits S A M; Renckens, Cees N M

    2010-01-01

    The Dutch parliament has recently accepted a tax law in which certain groups of alternative therapists can be exempt from VAT. To be eligible for this VAT exemption, the disciplines to which the therapists belong have to meet certain training requirements. In this article it is contended, in agreement with the Royal College of Physicians in the UK, that statutory regulation is inappropriate for disciplines whose therapies are neither of proved benefit nor appropriately tested. It legitimizes harmful therapies. This is illustrated by two serious accidents, previously described in this journal, caused by a chiropractor and a craniosacral therapist.

  19. THE ELM SURVEY. I. A COMPLETE SAMPLE OF EXTREMELY LOW-MASS WHITE DWARFS

    SciTech Connect

    Brown, Warren R.; Kilic, Mukremin; Kenyon, Scott J.; Prieto, Carlos Allende E-mail: mkilic@cfa.harvard.ed E-mail: callende@iac.e

    2010-11-10

    We analyze radial velocity observations of the 12 extremely low-mass (ELM), with {<=}0.25 M{sub sun}, white dwarfs (WDs) in the MMT Hypervelocity Star Survey. Eleven of the twelve WDs are binaries with orbital periods shorter than 14 hr; the one non-variable WD is possibly a pole-on system among our non-kinematically selected targets. Our sample is unique: it is complete in a well-defined range of apparent magnitude and color. The orbital mass functions imply that the unseen companions are most likely other WDs, although neutron star companions cannot be excluded. Six of the eleven systems with orbital solutions will merge within a Hubble time due to the loss of angular momentum through gravitational wave radiation. The quickest merger is J0923+3028, a g = 15.7 ELM WD binary with a 1.08 hr orbital period and a {<=}130 Myr merger time. The chance of a supernova Ia event among our ELM WDs is only 1%-7%, however. Three binary systems (J0755+4906, J1233+1602, and J2119-0018) have extreme mass ratios and will most likely form stable mass-transfer AM CVn systems. Two of these objects, SDSS J1233+1602 and J2119-0018, are the lowest surface gravity WDs ever found; both show Ca II absorption likely from accretion of circumbinary material. We predict that at least one of our WDs is an eclipsing detached double WD system, important for constraining helium core WD models.

  20. The ELM Survey. I. A Complete Sample of Extremely Low-mass White Dwarfs

    NASA Astrophysics Data System (ADS)

    Brown, Warren R.; Kilic, Mukremin; Allende Prieto, Carlos; Kenyon, Scott J.

    2010-11-01

    We analyze radial velocity observations of the 12 extremely low-mass (ELM), with <=0.25 M sun, white dwarfs (WDs) in the MMT Hypervelocity Star Survey. Eleven of the twelve WDs are binaries with orbital periods shorter than 14 hr; the one non-variable WD is possibly a pole-on system among our non-kinematically selected targets. Our sample is unique: it is complete in a well-defined range of apparent magnitude and color. The orbital mass functions imply that the unseen companions are most likely other WDs, although neutron star companions cannot be excluded. Six of the eleven systems with orbital solutions will merge within a Hubble time due to the loss of angular momentum through gravitational wave radiation. The quickest merger is J0923+3028, a g = 15.7 ELM WD binary with a 1.08 hr orbital period and a <=130 Myr merger time. The chance of a supernova Ia event among our ELM WDs is only 1%-7%, however. Three binary systems (J0755+4906, J1233+1602, and J2119-0018) have extreme mass ratios and will most likely form stable mass-transfer AM CVn systems. Two of these objects, SDSS J1233+1602 and J2119-0018, are the lowest surface gravity WDs ever found; both show Ca II absorption likely from accretion of circumbinary material. We predict that at least one of our WDs is an eclipsing detached double WD system, important for constraining helium core WD models. Based on observations obtained at the MMT Observatory, a joint facility of the Smithsonian Institution and the University of Arizona.

  1. Characteristics of the TFTR limiter H-mode: The transition, ELMs, transport and confinement

    SciTech Connect

    Bush, C.E.; Bretz, N.; Nazikian, R.; Stratton, B.C.; Synakowski, E.; Taylor, G. Budny, R.; Ramsey, A.T.; Scott, S.D.; Bell, M.; Bell, R.; Biglari, H.; Bitter, M.; Darrow, D.S.; Efthimion, P.; Fredrickson, E.D.; Hill, K.; Hsuan, H.; Kilpatrick, S.; McGuire, K.M.; Manos, D.; Mansfield, D.; Medley, S.S.; Mueller, D.; Park, H.; Paul, S.; Sabbagh, S.; Schivell, J.; Thompson, M.; Towner, H.H.; Wieland, R.M.; Zarnstorff, M.C.; Zweben, S.; Fonck, R.; Nagayama, Y.

    1992-11-01

    H-Modes obtained through transitions from the supershot regime have been studied on TFTR. The characteristics of these H-modes are similar to those found on other tokamaks with one main exception, the density prof:des can be highly peaked. In the best cases the enhanced confinement in the core of the initial supershot is retained in the H-mode phase, while the confinement in a broad edge region is enhanced. Thus in TFTR, all of the important physics of H-modes such as transitions, enhanced edge confinement, ELMs and other phenomena are studied in a large circular limiter tokamak with the added feature of centrally peaked density profiles and the advantage of an extensive set of diagnostics. The threshold power for the transition is found to be a linear function of plasma current. Transitions and ELMs are affected by the mix of co-and counter-neutral beam injection (NBI) and by perturbations introduced by pellet injection, gas puffing, and current ramping before and during NBI. Fluctuations near both transition and ELM events have been characterized. High frequency magnetic fluctuations in the range {ge} 100--250 kHz usually decrease during the transition. Microwave scattering spectra of density fluctuations in the plasma edge show a feature at high frequency during the H-mode, which is not observed in the plasma core and which is consistent with an edge poloidal rotation velocity, V{sub {theta}}, of {approximately} 10{sup 4} m/s. The fluctuations begin at the transition, propagate in the direction of electron diamagnetic drift, and have modulation correlated with ELMs. Several TFTR H-modes showed a modest improvement in confinement over that of the supershots from which they originated, and an understanding of these may eventually lead to a plasma with the combined advantages of both the supershot and the H-mode. The characteristics and physics of the TFTR H-modes are considered relative to other tokamaks and in light of various theoretical studies.

  2. Program ELM: A tool for rapid thermal-hydraulic analysis of solid-core nuclear rocket fuel elements

    NASA Technical Reports Server (NTRS)

    Walton, James T.

    1992-01-01

    This report reviews the state of the art of thermal-hydraulic analysis codes and presents a new code, Program ELM, for analysis of fuel elements. ELM is a concise computational tool for modeling the steady-state thermal-hydraulics of propellant flow through fuel element coolant channels in a nuclear thermal rocket reactor with axial coolant passages. The program was developed as a tool to swiftly evaluate various heat transfer coefficient and friction factor correlations generated for turbulent pipe flow with heat addition which have been used in previous programs. Thus, a consistent comparison of these correlations was performed, as well as a comparison with data from the NRX reactor experiments from the Nuclear Engine for Rocket Vehicle Applications (NERVA) project. This report describes the ELM Program algorithm, input/output, and validation efforts and provides a listing of the code.

  3. Host Acceptance and Larval Competition between the Invasive Banded and European Elm Bark Beetles, Scolytus schevyrewi and S. multistriatus (Coleoptera: Scolytidae): Potential Mechanisms for Competitive Displacement

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A recent survey revealed that the newly invasive banded elm bark beetle, Scolytus schevyrewi, was much more abundant than the long-established European elm bark beetle, S. multistriatus, in areas of Colorado and Wyoming, USA. This study sought to determine whether competitive displacement of S. mul...

  4. Comparison of ELM, GANN, WNN and empirical models for estimating reference evapotranspiration in humid region of Southwest China

    NASA Astrophysics Data System (ADS)

    Feng, Yu; Cui, Ningbo; Zhao, Lu; Hu, Xiaotao; Gong, Daozhi

    2016-05-01

    Reference evapotranspiration (ET0) is an essential component in hydrological ecological processes and agricultural water management. Accurate estimation of ET0 is of importance in improving irrigation efficiency, water reuse and irrigation scheduling. FAO-56 Penman-Monteith (P-M) model is recommended as the standard model to estimate ET0. Nevertheless, its application is limited due to the lack of required meteorological data. In this study, trained extreme learning machine (ELM), backpropagation neural networks optimized by genetic algorithm (GANN) and wavelet neural networks (WNN) models were developed to estimate ET0, and the performances of ELM, GANN, WNN, two temperature-based (Hargreaves and modified Hargreaves) and three radiation-based (Makkink, Priestley-Taylor and Ritchie) ET0 models in estimating ET0 were evaluated in a humid area of Southwest China. Results indicated that among the new proposed models, ELM and GANN models were much better than WNN model, and the temperature-based ELM and GANN models had better performance than Hargreaves and modified Hargreaves models, radiation-based ELM and GANN models had higher precision than Makkink, Priestley-Taylor and Ritchie models. Both of radiation-based ELM (RMSE ranging 0.312-0.332 mm d-1, Ens ranging 0.918-0.931, MAE ranging 0.260-0.300 mm d-1) and GANN models (RMSE ranging 0.300-0.333 mm d-1, Ens ranging 0.916-0.941, MAE ranging 0.2580-0.303 mm d-1) could estimate ET0 at an acceptable accuracy level, and are highly recommended for estimating ET0 without adequate meteorological data.

  5. Connection between plasma response and resonant magnetic perturbation (RMP) edge localized mode (ELM) suppression in DIII-D

    DOE PAGES

    Wingen, Andreas; Ferraro, N. M.; Shafer, Morgan W.; ...

    2015-09-03

    Calculations of the plasma response to applied non-axisymmetric fields in several DIII-D discharges show that predicted displacements depend strongly on the edge current density. This result is found using both a linear two-fluid-MHD model (M3D-C1) and a nonlinear ideal-MHD model (VMEC). Furthermore, it is observed that the probability of a discharge being edge localized mode (ELM)-suppressed is most closely related to the edge current density, as opposed to the pressure gradient. It is found that discharges with a stronger kink response are closer to the peeling–ballooning stability limit in ELITE simulations and eventually cross into the unstable region, causing ELMsmore » to reappear. Thus for effective ELM suppression, the RMP has to prevent the plasma from generating a large kink response, associated with ELM instability. Experimental observations are in agreement with the finding; discharges which have a strong kink response in the MHD simulations show ELMs or ELM mitigation during the RMP phase of the experiment, while discharges with a small kink response in the MHD simulations are fully ELM suppressed in the experiment by the applied resonant magnetic perturbation. The results are cross-checked against modeled 3D ideal MHD equilibria using the VMEC code. The procedure of constructing optimal 3D equilibria for diverted H-mode discharges using VMEC is presented. As a result, kink displacements in VMEC are found to scale with the edge current density, similar to M3D-C1, but the displacements are smaller. A direct correlation in the flux surface displacements to the bootstrap current is shown.« less

  6. ELM phenomenon as an interaction between bootstrap-current driven peeling modes and pressure-driven ballooning modes

    NASA Astrophysics Data System (ADS)

    Saarelma, S.; Günter, S.; Kurki-Suonio, T.; Zehrfeld, H.-P.

    2000-05-01

    An ELMy ASDEX Upgrade plasma equilibrium is reconstructed taking into account the bootstrap current. The peeling mode stability of the equilibrium is numerically analysed using the GATO [1] code, and it is found that the bootstrap current can drive the plasma peeling mode unstable. A high-n ballooning mode stability analysis of the equilibria revealed that, while destabilizing the peeling modes, the bootstrap current has a stabilizing effect on the ballooning modes. A combination of these two instabilities is a possible explanation for the type I ELM phenomenon. A triangularity scan showed that increasing triangularity stabilizes the peeling modes and can produce ELM-free periods observed in the experiments.

  7. Woodland Detection.

    ERIC Educational Resources Information Center

    Fischer, Richard B.

    1989-01-01

    Presents tips on nature observation during a woodland hike in the Adirondacks. Discusses engraver beetles and Dutch elm disease, birds' nests, hornets' nests, caterpillar webs, deer and bear signs, woodpecker holes, red squirrels, porcupine and beaver signs, and galls. (SV)

  8. Design Of JET ELM Control Coils For Operation At 350 C

    SciTech Connect

    Zatz, I J; Brooks, A; Cole, M; Neilson, G H; Lowry, C; Mardenfeld, M; Omran, H; Thompson, V; Todd, T

    2010-09-20

    A study has confirmed the feasibility of designing, fabricating and installing resonant magnetic field perturbation (RMP) coils in JET1 with the objective of controlling edge localized modes (ELM). A system of two rows of in-vessel coils, above the machine midplane, has been chosen as it not only can investigate the physics of and achieve the empirical criteria for ELM suppression, but also permits variation of the spectra allowing for comparison with other experiments. These coils present several engineering challenges. Conditions in JET necessitate the installation of these coils via remote handling, which will impose weight, dimensional and logistical limitations. And while the encased coils are designed to be conventionally wound and bonded, they will not have the usual benefit of active cooling. Accordingly, coil temperatures are expected to reach 350 C during bakeout as well as during plasma operations. These elevated temperatures are beyond the safe operating limits of conventional OFHC copper and the epoxies that bond and insulate the turns of typical coils. This has necessitated the use of an alternative copper alloy conductor C18150 (CuCrZr). More importantly, an alternative to epoxy had to be found. An R&D program was initiated to find the best available insulating and bonding material. The search included polyimides and ceramic polymers. The scope and status of this R&D program, as well as the critical engineering issues encountered to date are reviewed and discussed.

  9. Impurity migration with RF sheath and ELMs perturbed electric field in tokamak

    NASA Astrophysics Data System (ADS)

    Gui, Bin; Xiao, Xiaotao; Tang, Tengfei; Xu, Xueqiao

    2016-10-01

    In radio frequency (RF) experiments, impurity generation and transport are important due to the phenomenon of RF enhanced impurity generation. In BOUT + + framework, the equilibrium radial electric field with RF sheath boundary condition on the limiter or the divertor surface is self-consistently calculated by using a two-field model. Based on this self-consistent calculation, it is found the positive radial electric field forms in the SOL region which qualitatively agrees with the experimental on the TEXTOR. The test particle module is developed in BOUT + + framework to simulate both turbulence and neoclassical physics in realistic geometry. Firstly, the drift orbit is calculated in cylinder coordinates due to singularity of x-point in flux coordinate. The turbulence transport of impurity generated from hot spot of RF limiter is simulated by random walk model. The numerical results show that less impurities will migrate into core and divertor region, more impurities migrate into nearby SOL boundary when turbulence transport enhanced. Then the effect of RF sheath potential on impurity migration will be simulated. Using the perturbed electric field from our BOUT + + nonlinear ELMs simulation, the transport of the impurities in different phase of ELMs are also discussed. USDOE by LLNL under DE-AC52-07NA27344.

  10. Adaptive phenotypic plasticity of Siberian elm in response to drought stress: increased stomatal pore depth.

    PubMed

    Park, Go Eun; Kim, Ki Woo; Lee, Don Koo; Hyun, Jung Oh

    2013-08-01

    Leaf stomatal characteristics of Siberian elm (Ulmus pumila) were investigated by electron microscopy and white light scanning interferometry. On the basis of average annual precipitations, two types of tree specimens were collected from Korea, China, and Mongolia: (1) trees under normal environmental conditions and (2) trees under arid conditions. Field emission scanning electron microscopy revealed oval-shaped stomata on the lower surface, and they were ca. 20 μm in width. In-lens secondary electron imaging showed differences in electron density and stomatal pore depth between the two types. According to the line profile analysis by white light scanning interferometry, stomata under arid conditions appeared to have higher levels of the stomatal pore depth than ones under normal conditions. Focused ion beam-field emission electron microscopy supported the increased stomatal pore depth with the increasing drought stress gradient. These results suggest that complementary microscopy can be employed to unravel the adaptive phenotypic plasticity of Siberian elm in response to drought stress.

  11. Aquifer test to determine hydraulic properties of the Elm aquifer near Aberdeen, South Dakota

    USGS Publications Warehouse

    Schaap, Bryan D.

    2000-01-01

    The Elm aquifer, which consists of sandy and gravelly glacial-outwash deposits, is present in several counties in northeastern South Dakota. An aquifer test was conducted northeast of Aberdeen during the fall of 1999 to determine the hydraulic properties of the Elm aquifer in that area. An improved understanding of the properties of the aquifer will be useful in the possible development of the aquifer as a water resource. Historical water-level data indicate that the saturated thickness of the Elm aquifer can change considerably over time. From September 1977 through November 1985, water levels at three wells completed in the Elm aquifer near the aquifer test site varied by 5.1 ft, 9.50 ft, and 11.1 ft. From June 1982 through October 1999, water levels at five wells completed in the Elm aquifer near the aquifer test site varied by 8.7 ft, 11.4 ft, 13.2 ft, 13.8 ft, and 19.7 ft. The water levels during the fall of 1999 were among the highest on record, so the aquifer test was affected by portions of the aquifer being saturated that might not be saturated during drier times. The aquifer test was conducted using five existing wells that had been installed prior to this study. Well A, the pumped well, has an operating irrigation pump and is centrally located among the wells. Wells B, C, D, and E are about 70 ft, 1,390 ft, 2,200 ft, and 3,100 ft, respectively, in different directions from Well A. Using vented pressure transducers and programmable data loggers, water-level data were collected at the five wells prior to, during, and after the pumping, which started on November 19, 1999, and continued a little over 72 hours. Based on available drilling logs, the Elm aquifer near the test area was assumed to be unconfined. The Neuman (1974) method theoretical response curves that most closely match the observed water-level changes at Wells A and B were calculated using software (AQTESOLV for Windows Version 2.13-Professional) developed by Glenn M. Duffield of Hydro

  12. Recrystallization and grain growth induced by ELMs-like transient heat loads in deformed tungsten samples.

    PubMed

    Suslova, A; El-Atwani, O; Sagapuram, D; Harilal, S S; Hassanein, A

    2014-11-04

    Tungsten has been chosen as the main candidate for plasma facing components (PFCs) due to its superior properties under extreme operating conditions in future nuclear fusion reactors such as ITER. One of the serious issues for PFCs is the high heat load during transient events such as ELMs and disruption in the reactor. Recrystallization and grain size growth in PFC materials caused by transients are undesirable changes in the material, since the isotropic microstructure developed after recrystallization exhibits a higher ductile-to-brittle transition temperature which increases with the grain size, a lower thermal shock fatigue resistance, a lower mechanical strength, and an increased surface roughening. The current work was focused on careful determination of the threshold parameters for surface recrystallization, grain growth rate, and thermal shock fatigue resistance under ELM-like transient heat events. Transient heat loads were simulated using long pulse laser beams for two different grades of ultrafine-grained tungsten. It was observed that cold rolled tungsten demonstrated better power handling capabilities and higher thermal stress fatigue resistance compared to severely deformed tungsten. Higher recrystallization threshold, slower grain growth, and lower degree of surface roughening were observed in the cold rolled tungsten.

  13. Recrystallization and grain growth induced by ELMs-like transient heat loads in deformed tungsten samples

    PubMed Central

    Suslova, A.; El-Atwani, O.; Sagapuram, D.; Harilal, S. S.; Hassanein, A.

    2014-01-01

    Tungsten has been chosen as the main candidate for plasma facing components (PFCs) due to its superior properties under extreme operating conditions in future nuclear fusion reactors such as ITER. One of the serious issues for PFCs is the high heat load during transient events such as ELMs and disruption in the reactor. Recrystallization and grain size growth in PFC materials caused by transients are undesirable changes in the material, since the isotropic microstructure developed after recrystallization exhibits a higher ductile-to-brittle transition temperature which increases with the grain size, a lower thermal shock fatigue resistance, a lower mechanical strength, and an increased surface roughening. The current work was focused on careful determination of the threshold parameters for surface recrystallization, grain growth rate, and thermal shock fatigue resistance under ELM-like transient heat events. Transient heat loads were simulated using long pulse laser beams for two different grades of ultrafine-grained tungsten. It was observed that cold rolled tungsten demonstrated better power handling capabilities and higher thermal stress fatigue resistance compared to severely deformed tungsten. Higher recrystallization threshold, slower grain growth, and lower degree of surface roughening were observed in the cold rolled tungsten. PMID:25366885

  14. METHANE PENTRATION IN DIII-D ELMing H-MODE PLASMAS

    SciTech Connect

    W.P. WEST; C.J. LASNIER; D.G. WHYTE; R.C. ISLER; T.E. EVANS; G.L. JACKSON; D.L. RUDAKOV; M.R. WADE; J. STRACHAN

    2002-06-01

    Carbon penetration into the core plasma during midplane and divertor methane puffing has been measured for DIII-D ELMing H-mode plasmas. The methane puffs are adjusted to a measurable signal, but global plasma parameters are only weakly affected (line average density, increases by < 10%, energy confinement time, {tau}{sub E} drops by < 10%). The total carbon content is derived from C{sup +6} density profiles in the core measured as a function of time using charge exchange recombination spectroscopy. The methane penetration factor is defined as the difference in the core content with the puff on and puff off, divided by the carbon confinement time and the methane puffing rate. In ELMing H-mode discharges with ion {del}B drift direction into the X-point, increasing the line averaged density from 5 to 8 x 10{sup 19} m{sup -3} dropped the penetration factor from 6.6% to 4.6% for main chamber puffing. The penetration factor for divertor puffing was below the detection limit (<1%). Changing the ion {del}B drift direction to away from the X-point decreased the penetration factor by more than a factor of five for main chamber puffing.

  15. Pedestal shape, stability and inter-ELM evolution for different main ion species in ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Laggner, Florian M.

    2016-10-01

    In tokamak plasmas with different main ion species as hydrogen isotopes or helium, a change of confinement occurs, known as isotope effect. To identify the processes defining the pedestal structure and evolution, experiments comparing hydrogen (H), deuterium (D) and helium (He) plasmas have been performed. Their goal was to match the pedestal top electron density and temperatures and compare the pedestal shape and stability. A factor of almost 10 higher gas puff as well as a factor of 2 higher heating power were required in H to achieve the same pedestal top values as in the D reference. While the pedestal electron temperature profiles do not differ, the density profile in H has shallower gradients. These can be explained by a lower particle confinement in H, if the ionization source profile is assumed to be similar. In He plasmas owing to the larger effective charge, the stored energy at similar pedestal top electron density is roughly a factor of 1.5 smaller than in the references, leading to the absence of ELMs. In summary the experimental results suggest different particle and energy confinement for different main ion species, however, peeling-ballooning theory can sufficiently describe the pedestal stability and ELM behavior. This work has been carried out within the framework of the EUROfusion Consortium and has received funding from the Euratom research and training programme 2014-2018 under Grant Agreement No. 633053.

  16. A computer aided diagnosis system for thyroid disease using extreme learning machine.

    PubMed

    Li, Li-Na; Ouyang, Ji-Hong; Chen, Hui-Ling; Liu, Da-You

    2012-10-01

    In this paper, we present an effective and efficient computer aided diagnosis (CAD) system based on principle component analysis (PCA) and extreme learning machine (ELM) to assist the task of thyroid disease diagnosis. The CAD system is comprised of three stages. Focusing on dimension reduction, the first stage applies PCA to construct the most discriminative new feature set. After then, the system switches to the second stage whose target is model construction. ELM classifier is explored to train an optimal predictive model whose parameters are optimized. As we known, the number of hidden neurons has an important role in the performance of ELM, so we propose an experimental method to hunt for the optimal value. Finally, the obtained optimal ELM model proceeds to perform the thyroid disease diagnosis tasks using the most discriminative new feature set and the optimal parameters. The effectiveness of the resultant CAD system (PCA-ELM) has been rigorously estimated on a thyroid disease dataset which is taken from UCI machine learning repository. We compare it with other related methods in terms of their classification accuracy. Experimental results demonstrate that PCA-ELM outperforms other ones reported so far by 10-fold cross-validation method, with the mean accuracy of 97.73% and with the maximum accuracy of 98.1%. Besides, PCA-ELM performs much faster than support vector machines (SVM) based CAD system. Consequently, the proposed method PCA-ELM can be considered as a new powerful tools for diagnosing thyroid disease with excellent performance and less time.

  17. Development concept for Dutch user support

    NASA Astrophysics Data System (ADS)

    Pronk, C. N. A.; Koopman, N.; Dehoop, D.

    1992-06-01

    The main development approaches and some technologies developed in support of the different objectives of the Dutch Utilization Center (DUC) are reported. The DUC acts as a point of coordination of Dutch user support activities. The support needs of the user are analyzed and from there the required support efforts of the entities in the Dutch User Support Organization (DUSO) are activated. The main objectives of the DUSO are to promote the availability of the Columbus Space Station infrastructure among potential Dutch users, and to assist the users during the process of experiment definition, development, execution, and results evaluation. The DUSO support activities cover promotion and familiarization, and administrative, scientific, technical, and operational support to microgravity and space experimentation. The DUC developmental approaches consist of two approaches: a top down or formal approach; and a bottom up approach.

  18. Role of plasma shape in access to ELM suppression at low collisionality: First observation of ELM suppression in ASDEX Upgrade in a shape-matching identity experiment with DIII-D

    NASA Astrophysics Data System (ADS)

    Suttrop, Wolfgang; Nazikian, Raffi; Kirk, Andrew; ASDEX Upgrade Team; Diii-D Team; Eurofusion Mst1 Team

    2016-10-01

    Controlled plasma shape scans at low pedestal collisionality νped* < 0.4 in DIII-D reveal that the threshold of magnetic perturbation field strength for suppression of edge-localized modes (ELMs) depends on both upper and lower plasma triangularity. Similar plasmas with matching shape and matching plasma parameters have been performed in DIII-D and ASDEX Upgrade. In these discharges, stationary ELM suppression by magnetic perturbations is observed for the first time in ASDEX Upgrade.Despite different divertor geometry and different first wall materials in the two machines, these plasmas show many similarities: Complete ELM suppression occurs in a narrow windows around q95 3.7 with transitions to phases with ``fuzzy'' ELMs outside these windows, electron density and temperature profiles as well as the total pedestal pressure are well matched, while there are variations of other quantities such as impurity concentrations and impurity rotation frequencies. A first experiment with injection of tungsten shows that the tungsten impurity content in the plasma decays on the time scale of energy confinement. see http://www.euro-fusionscipub.org/mst1.

  19. Slippery Elm

    MedlinePlus

    ... is applied to the skin for wounds, burns, gout, rheumatism, cold sores, boils, abscesses, ulcers, toothaches, sore ... infection. Burns and wounds. Coughs. Colic. Constipation. Diarrhea. Gout. Hemorrhoids. Herpes. Rheumatism. Stomach ulcers. Syphilis. Tapeworm. Toothache. ...

  20. Description and phylogeny of a new microsporidium from the elm leaf beetle, Xanthogaleruca luteola Muller, 1766 (Coleoptera: Chrysomelidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This study describes a new genus and species of microsporidia which is a pathogen of the elm leaf beetle, Xanthogaleruca luteola Muller, 1776 (Coleoptera: Chrysomelidae). The beetles were collected from Istanbul in Turkey. All developmental stages are uninucleate and in direct contact with the host ...

  1. Effect of n = 3 perturbation field amplitudes below the ELM triggering threshold on edge and SOL transport in NSTX

    DOE PAGES

    J. M. Canik; Lore, J. D.; Ahn, J. -W.; ...

    2013-01-12

    Here, the pulsed application of n = 3 magnetic perturbation fields with amplitudes below that which triggers ELMs results in distinct, transient responses observable on several edge and divertor diagnostics in NSTX. We refer to these responses as Sub-Threshold Edge Perturbations (STEPs). An analysis of edge measurements suggests that STEPs result in increased transport in the plasma edge and scrape-off layer, which leads to augmentation of the intrinsic strike point splitting due to error fields, i.e., an intensification of the helical divertor footprint flux pattern. These effects are much smaller in magnitude than those of triggered ELMs, and are observedmore » for the duration of the field perturbation measured internal to the vacuum vessel. In addition, STEPs are correlated with changes to the MHD activity, along with transient reductions in the neutron production rate. Ideally the STEPs could be used to provide density control and prevent impurity accumulation, in the same manner that on-demand ELM triggering is used on NSTX, without the impulsive divertor fluxes and potential for damage to plasma facing components associated with ELMs.« less

  2. Intake of dietary phytoestrogens by Dutch women.

    PubMed

    Boker, Lital Keinan; Van der Schouw, Yvonne T; De Kleijn, Miriam J J; Jacques, Paul F; Grobbee, Diederick E; Peeters, Petra H M

    2002-06-01

    Higher consumption of phytoestrogens might be protective against certain chronic diseases. Accurate quantification of habitual phytoestrogen intake is important for assessing associations between phytoestrogens and risk for certain diseases. The aim of this study was to estimate dietary intake of phytoestrogens in Dutch middle-aged and elderly women and to describe their main sources. Women were recruited between 1993 and 1997 and aged 50-69 y at enrollment (Prospect-EPIC; n = 17,357). A detailed food frequency questionnaire referring to the preceding year was filled in at recruitment. A literature search was conducted to obtain data regarding content of the isoflavones daidzein, genistein, formononetin, biochanin A, the coumestan coumesterol and the lignans matairesinol and secoisolariciresinol in relevant food items. Concentrations of each phytoestrogen in each food item were subsequently grouped by seven categories; group scores were multiplied by daily intakes of food items and then summed across food items to produce for each participant a total daily intake score for each phytoestrogen. Approximately 75% of participants were postmenopausal at recruitment. The mean age was 57 y. Geometric means of daily intake of daidzein, genistein, formononetin, biochanin A, coumesterol, matairesinol and secoisolariciresinol were 0.15, 0.16, 0.08, 0.001, <0.001, 0.07 and 0.93 mg, respectively. The main sources for isoflavones were peas and beans, nuts, grain products, coffee, tea and soy products. The main sources for coumestans were peas, beans and other vegetables. The main sources of lignans were grain products, fruit and alcoholic beverages (red and white wines). We conclude that intake levels of phytoestrogen in our study population are low; however, they are comparable with intake levels previously reported for other Western cohorts. In this population, phytoestrogen intake consisted largely of lignans.

  3. Estimation of in-situ bioremediation system cost using a hybrid Extreme Learning Machine (ELM)-particle swarm optimization approach

    NASA Astrophysics Data System (ADS)

    Yadav, Basant; Ch, Sudheer; Mathur, Shashi; Adamowski, Jan

    2016-12-01

    In-situ bioremediation is the most common groundwater remediation procedure used for treating organically contaminated sites. A simulation-optimization approach, which incorporates a simulation model for groundwaterflow and transport processes within an optimization program, could help engineers in designing a remediation system that best satisfies management objectives as well as regulatory constraints. In-situ bioremediation is a highly complex, non-linear process and the modelling of such a complex system requires significant computational exertion. Soft computing techniques have a flexible mathematical structure which can generalize complex nonlinear processes. In in-situ bioremediation management, a physically-based model is used for the simulation and the simulated data is utilized by the optimization model to optimize the remediation cost. The recalling of simulator to satisfy the constraints is an extremely tedious and time consuming process and thus there is need for a simulator which can reduce the computational burden. This study presents a simulation-optimization approach to achieve an accurate and cost effective in-situ bioremediation system design for groundwater contaminated with BTEX (Benzene, Toluene, Ethylbenzene, and Xylenes) compounds. In this study, the Extreme Learning Machine (ELM) is used as a proxy simulator to replace BIOPLUME III for the simulation. The selection of ELM is done by a comparative analysis with Artificial Neural Network (ANN) and Support Vector Machine (SVM) as they were successfully used in previous studies of in-situ bioremediation system design. Further, a single-objective optimization problem is solved by a coupled Extreme Learning Machine (ELM)-Particle Swarm Optimization (PSO) technique to achieve the minimum cost for the in-situ bioremediation system design. The results indicate that ELM is a faster and more accurate proxy simulator than ANN and SVM. The total cost obtained by the ELM-PSO approach is held to a minimum

  4. Microsatellite markers for the critically endangered elm species Ulmus gaussenii (Ulmaceae).

    PubMed

    Geng, Qi-Fang; Yang, Jie; He, Jia; Wang, Dan-Bi; Shi, En; Xu, Wei-Xiang; Jeelani, Nasreen; Wang, Zhong-Sheng; Liu, Hong

    2016-07-20

    The Anhui elm Ulmus gaussenii is listed as a critically endangered species by the International Union for Conservation of Nature and is endemic to China, where its only population is restricted to Langya Mountain in Chuzhou, Anhui Province. To better understand the population genetics of U. gaussenii, we developed 12 microsatellite markers using an improved technique. The 12 markers were polymorphic, with the number of alleles per locus ranging from two to nine. Observed and expected heterozygosities ranged from 0.021 to 0.750 and 0.225 to 0.744, respectively. The inbreeding coefficient ranged from -0.157 to 0.960. Significant linkage disequilibrium was detected for two pairs of loci, and significant deviations from Hardy-Weinberg equilibrium were found in nine loci. These microsatellite markers will contribute to the studies of population genetics in U. gaussenii, which in turn will contribute to species conservation and protection.

  5. Surface damage characteristics of CFC and tungsten with repetitive ELM-like pulsed plasma irradiation

    NASA Astrophysics Data System (ADS)

    Kikuchi, Y.; Nishijima, D.; Nakatsuka, M.; Ando, K.; Higashi, T.; Ueno, Y.; Ishihara, M.; Shoda, K.; Nagata, M.; Kawai, T.; Ueda, Y.; Fukumoto, N.; Doerner, R. P.

    2011-08-01

    Surface damage of carbon fiber composite (CFC) and tungsten (W) due to repetitive ELM-like pulsed plasma irradiation has been investigated by using a magnetized coaxial plasma gun. CX2002U CFC and stress-relieved W samples were exposed to repetitive pulsed deuterium plasmas with duration of ˜0.5 ms, incident ion energy of ˜30 eV, and surface absorbed energy density of ˜0.3-0.7 MJ/m2. Bright spots on a CFC surface during pulsed plasma exposures were clearly observed with a high-speed camera, indicating a local surface heating. No melting of a W surface was observed under a single plasma pulse exposure at energy density of ˜0.7 MJ/m2, although cracks were formed. Cracking of the W surface grew with repetitive pulsed plasma exposures. Subsequently, the surface melted due to localized heat absorption.

  6. Surface damage of W exposed to combined stationary D plasma and ELMs-like pulsed plasma

    NASA Astrophysics Data System (ADS)

    Jia, Y. Z.; Liu, W.; Xu, B.; Qu, S. L.; Morgan, T. W.

    2017-04-01

    The surface damage of W under D plasma and ELMs-like transient heat loads was studied by combined stationary and pulsed D plasma. Low-flux transient heat loads will promote blister formation due to the gas expansion inside the blisters. On the contrary, high-flux transient heat loads will mitigate blistering due to the high surface temperature. Therefore, blistering on W surface first increased and then decreased with the increasing transient heat loads. The promotion effect of pulsed plasma on blistering is more obvious on [001] and [110] surfaces than on [111] surface, and the orientation dependence of blisters was mitigated by the transient heat loads. Surface modification induced by transient heat loads only formed on [001] and [110] surfaces, but did not form on [111] surface. The orientation dependence of surface modification was mainly due to the slipping system of dislocations.

  7. CFRP damage identification system based on FBG sensors and ELM method

    NASA Astrophysics Data System (ADS)

    Lu, Shizeng; Jiang, Mingshun; Jia, Lei; Sui, Qingmei; Sai, Yaozhang

    2015-02-01

    The identification of the damage state of Carbon fiber-reinforced plastic (CFRP) structure is the necessary information for ensuring the safety of CFRP structure. In this paper, the structural damage identification system using fiber Bragg grating (FBG) sensors and the damage identification method were investigated. FBG sensors were used to detect the structural dynamic response signal, which was generated by an active actuation way. Fourier transform and principal component analysis (PCA) were used to extract the damage characteristic. After that, the structural damage identification model was constructed based on extreme learning machine (ELM), whose input is the damage characteristic and output is the damage state. Finally, the damage identification system was established and verified on a CFRP plate with 160 mm160 mm experiment area. The experimental results showed that the identification accuracy was more than 90 %. This paper provided a reliable method for CFRP structural damage identification.

  8. Effect of collisional temperature isotropisation on ELM parallel transport in a tokamak scrape-off layer

    NASA Astrophysics Data System (ADS)

    Coulette, David; Hirstoaga, Sever A.; Manfredi, Giovanni

    2016-08-01

    We develop a hybrid model to describe the parallel transport in a tokamak scrape-off layer following an edge-localized mode (ELM) event. The parallel dynamics is treated with a kinetic Vlasov-Poisson model, while the evolution of the perpendicular temperature {{T}\\bot} is governed by a fluid equation. The coupling is ensured by isotropising collisions. The model generalises an earlier approach where {{T}\\bot} was constant in space and time (Manfredi et al 2011 Plasma Phys. Control. Fusion 53 015012). Numerical results show that the main effect comes from electron-electron collisions, which limit the decrease of the parallel electron temperature and increase the potential drop in the Debye sheath in front of the surface. Ion-ion collisions have an almost negligible impact. The net effect is an increased peak power load on the target plates.

  9. Scrape-off Layer Current Model for Filament Structure Observed during Edge Localized Modes (ELMs) in the DIII-D Tokamak

    SciTech Connect

    Takahashi, Hironori; Fredrickson, E. D.; Schaffer, M. J.

    2008-04-15

    The plasma in tokamaks often exhibits a relaxation oscillation called the edge localized mode (ELM), which is generally attributed to MHD instability driven by strong gradients at the plasma boundary. It is shown here that field-aligned currents flowing just outside the boundary may also play a role in the ELM process. The poloidal perturbation magnetic field during ELMs in the DIII–D tokamak calculated from measured currents can reproduce prominent observed features, including a narrow magnetic structure at the outboard midplane similar to filaments observed earlier in DIII–D and NSTX.

  10. ELM simulation experiments using transient heat and particle load produced by a magnetized coaxial plasma gun

    NASA Astrophysics Data System (ADS)

    Shoda, K.; Sakuma, I.; Iwamoto, D.; Kikuchi, Y.; Fukumoto, N.; Nagata, M.

    2011-10-01

    It is considered that thermal transient events such as type I edge-localized modes (ELMs) and disruptions will limit the lifetime of plasma-facing components (PFCs) in ITER. It is predicted that the heat load onto the PFCs during type I ELMs in ITER is 0.2-2MJ/m2 with pulse length of ~0.1-1ms. We have investigated interaction between transient heat and particle load and the PFCs by using a magnetized coaxial plasma gun (MCPG) at University of Hyogo. In the experiment, a pulsed plasma with duration of ~0.5ms, incident ion energy of ~30eV, and surface absorbed energy density of ~0.3-0.7MJ/m2 was produced by the MCPG. However, no melting occurred on a tungsten surface exposed to a single plasma pulse of ~0.7MJ/m2, while cracks clearly appeared at the edge part of the W surface. Thus, we have recently started to improve the performance of the MCPG in order to investigate melt layer dynamics of a tungsten surface such as vapor cloud formation. In the modified MCPG, the capacitor bank energy for the plasma discharge is increased from 24.5 kJ to 144 kJ. In the preliminary experiments, the plasmoid with duration of ~0.6 ms, incident ion energy of ~ 40 eV, and the surface absorbed energy density of ~2 MJ/m2 was successfully produced at the gun voltage of 6 kV.

  11. Cold tolerance and supercooling capacity in overwintering adults of elm leaf beetle Xanthogaleruca luteola (Coleoptera: Chrysomelidae).

    PubMed

    Soudi, Sh; Moharramipour, S

    2011-12-01

    Elm leaf beetle, Xanthogaleruca luteola (Muller) is one of the key pests of elm trees all over the world, and survives winter in reproductive diapause in sheltered locations. Seasonal variation of whole body supercooling points (SCPs), LT50 (temperature at which 50% of the test individuals die) and survival rate after exposure to subzero temperatures were determined in field collected adults during October 2008 to May 2009 and October 2009 to May 2010. The SCP of adults decreased significantly from October (median=-13.8°C) to January (median=-20.7°C) in first year, relatively similar results was observed in the second year. The lowest LT50 was observed in overwintering adults collected in January (-16.81°C) in the first year and December (-15.59°C) in the second year. Mortality at -15°C for 24 h was >70% in early autumn in both years whereas it decreased to lower than 45% in early winter, the highest mortality (100%) was observed in adults collected in May in both years. Cold acclimated adults (30 d, 5°C) in November 2008 exhibited significantly higher SCP (-12.21±0.64°C) than nonacclimated adults (-15.57±1.35°C). A 30-d exposure to 5°C caused >20% mortality in November, while <9% mortality was observed in adults collected in December and January 2008. Overwintering adults died upon freezing and the lower lethal temperatures were within the range of SCP, indicating that X. luteola is a freeze intolerant insect.

  12. Nonlinear ELM simulations based on a nonideal peeling–ballooning model using the BOUT++ code

    DOE PAGES

    Xu, X. Q.; Dudson, B. D.; Snyder, P. B.; ...

    2011-09-23

    A minimum set of equations based on the peeling–ballooning (P–B) model with nonideal physics effects (diamagnetic drift, E × B drift, resistivity and anomalous electron viscosity) is found to simulate pedestal collapse when using the BOUT++ simulation code, developed in part from the original fluid edge code BOUT. Linear simulations of P–B modes find good agreement in growth rate and mode structure with ELITE calculations. The influence of the E × B drift, diamagnetic drift, resistivity, anomalous electron viscosity, ion viscosity and parallel thermal diffusivity on P–B modes is being studied; we find that (1) the diamagnetic drift and Emore » × B drift stabilize the P–B mode in a manner consistent with theoretical expectations; (2) resistivity destabilizes the P–B mode, leading to resistive P–B mode; (3) anomalous electron and parallel ion viscosities destabilize the P–B mode, leading to a viscous P–B mode; (4) perpendicular ion viscosity and parallel thermal diffusivity stabilize the P–B mode. With addition of the anomalous electron viscosity under the assumption that the anomalous kinematic electron viscosity is comparable to the anomalous electron perpendicular thermal diffusivity, or the Prandtl number is close to unity, it is found from nonlinear simulations using a realistic high Lundquist number that the pedestal collapse is limited to the edge region and the ELM size is about 5–10% of the pedestal stored energy. Furthermore, this is consistent with many observations of large ELMs. The estimated island size is consistent with the size of fast pedestal pressure collapse. In the stable α-zones of ideal P–B modes, nonlinear simulations of viscous ballooning modes or current-diffusive ballooning mode (CDBM) for ITER H-mode scenarios are presented.« less

  13. Nonlinear ELM simulations based on a nonideal peeling–ballooning model using the BOUT++ code

    SciTech Connect

    Xu, X. Q.; Dudson, B. D.; Snyder, P. B.; Umansky, M. V.; Wilson, H. R.; Casper, T.

    2011-09-23

    A minimum set of equations based on the peeling–ballooning (P–B) model with nonideal physics effects (diamagnetic drift, E × B drift, resistivity and anomalous electron viscosity) is found to simulate pedestal collapse when using the BOUT++ simulation code, developed in part from the original fluid edge code BOUT. Linear simulations of P–B modes find good agreement in growth rate and mode structure with ELITE calculations. The influence of the E × B drift, diamagnetic drift, resistivity, anomalous electron viscosity, ion viscosity and parallel thermal diffusivity on P–B modes is being studied; we find that (1) the diamagnetic drift and E × B drift stabilize the P–B mode in a manner consistent with theoretical expectations; (2) resistivity destabilizes the P–B mode, leading to resistive P–B mode; (3) anomalous electron and parallel ion viscosities destabilize the P–B mode, leading to a viscous P–B mode; (4) perpendicular ion viscosity and parallel thermal diffusivity stabilize the P–B mode. With addition of the anomalous electron viscosity under the assumption that the anomalous kinematic electron viscosity is comparable to the anomalous electron perpendicular thermal diffusivity, or the Prandtl number is close to unity, it is found from nonlinear simulations using a realistic high Lundquist number that the pedestal collapse is limited to the edge region and the ELM size is about 5–10% of the pedestal stored energy. Furthermore, this is consistent with many observations of large ELMs. The estimated island size is consistent with the size of fast pedestal pressure collapse. In the stable α-zones of ideal P–B modes, nonlinear simulations of viscous ballooning modes or current-diffusive ballooning mode (CDBM) for ITER H-mode scenarios are presented.

  14. 1. PANORAMA, SHOWING COMMAND POST RELATION TO DUTCH HARBOR AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. PANORAMA, SHOWING COMMAND POST RELATION TO DUTCH HARBOR AND UNALASKA FROM THE TOP OF LITTLE SOUTH AMERICA - Naval Operating Base Dutch Harbor & Fort Mears, Hill 400 Fixed Defense Battery Command Post, Unalaska, Aleutian Islands, AK

  15. PANORAMA, SHOWING COMMAND POST RELATION TO DUTCH HARBOR AND UNALASKA ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PANORAMA, SHOWING COMMAND POST RELATION TO DUTCH HARBOR AND UNALASKA FROM THE TOP OF LITTLE SOUTH AMERICA - Naval Operating Base Dutch Harbor & Fort Mears, Hill 400 Fixed Defense Battery Command Post, Unalaska, Aleutian Islands, AK

  16. DNA barcoding of Dutch birds

    PubMed Central

    Aliabadian, Mansour; Beentjes, Kevin K.; Roselaar, C.S. (Kees); van Brandwijk, Hans; Nijman, Vincent; Vonk, Ronald

    2013-01-01

    Abstract The mitochondrial cytochrome c oxidase subunit I (COI) can serve as a fast and accurate marker for the identification of animal species, and has been applied in a number of studies on birds. We here sequenced the COI gene for 387 individuals of 147 species of birds from the Netherlands, with 83 species being represented by > 2 sequences. The Netherlands occupies a small geographic area and 95% of all samples were collected within a 50 km radius from one another. The intraspecific divergences averaged 0.29% among this assemblage, but most values were lower; the interspecific divergences averaged 9.54%. In all, 95% of species were represented by a unique barcode, with 6 species of gulls and skua (Larus and Stercorarius) having at least one shared barcode. This is best explained by these species representing recent radiations with ongoing hybridization. In contrast, one species, the Lesser Whitethroat Sylvia curruca showed deep divergences, averaging 5.76% and up to 8.68% between individuals. These possibly represent two distinct taxa, S. curruca and S. blythi, both clearly separated in a haplotype network analysis. Our study adds to a growing body of DNA barcodes that have become available for birds, and shows that a DNA barcoding approach enables to identify known Dutch bird species with a very high resolution. In addition some species were flagged up for further detailed taxonomic investigation, illustrating that even in ornithologically well-known areas such as the Netherlands, more is to be learned about the birds that are present. PMID:24453549

  17. Metrical Segmentation in Dutch: Vowel Quality or Stress?

    ERIC Educational Resources Information Center

    Quene, Hugo; Koster, Mariette L.

    1998-01-01

    Examines metrical segmentation strategy in Dutch. The first experiment shows that stress strongly affects Dutch listeners' ability and speed in spotting Dutch monosyllabic words in disyllabic nonwords. The second experiment finds the same stress effect when only the target words are presented without a subsequent syllable triggering segmentation.…

  18. A Reference Grammar of Dutch, with Exercises and Key.

    ERIC Educational Resources Information Center

    Fehringer, Carol

    This textbook provides an accessible reference grammar of the Dutch language for English-speaking students of Dutch to help consolidate their knowledge through practical exercises on a whole range of grammatical topics. It is intended both for beginners and intermediate level students. Advanced learners of Dutch wishing to review particular…

  19. The Dutch Perspective on NATO Development during the Korean War

    DTIC Science & Technology

    2012-06-08

    government tried to get a favorable defensive line accepted in NATO, covering as much territory as possible. The Dutch lobbied for a blue water naval...interests within NATO. The Dutch government tried to get a favorable defensive line accepted in NATO, covering as much territory as possible. The Dutch...

  20. Learning Styles of Chinese and Dutch Students Compared within the Context of Dutch Higher Education in Life Sciences

    ERIC Educational Resources Information Center

    Biemans, Harm; Van Mil, Marc

    2008-01-01

    This study investigated the extent to which the learning styles of Chinese students differ from those of Dutch students. The study was conducted within the context of English language Bachelor of Science programmes that Wageningen University offers together with China Agricultural University to Dutch and Chinese students. Sixteen Dutch students…

  1. Tungsten divertor sourcing in DIII-D H-mode discharges and its impact on core impurity accumulation in different ELM regimes

    NASA Astrophysics Data System (ADS)

    Abrams, T.; Ding, R.; Guterl, J.; Briesemeister, A.; Unterberg, E. A.; Guo, H. Y.; Leonard, A. W.; Thomas, D. M.; McLean, A. G.; Victor, B.; Rudakov, D.; Grierson, B.; Watkins, J. G.; Elder, J. D.; Stangeby, P. C.

    2016-10-01

    Significant progress has been made understanding W sourcing during Type I ELMy H-mode on DIII-D using fast high-resolution measurements of W sourcing coupled with OEDGE/ERO and TRIM.SP modeling. ERO modeling of the inter-ELM phase, using a new OEDGE capability for charge state-resolved carbon ion fluxes and a material mixing model, shows measured W erosion is well explained by C- >W sputtering. Ion impact energies in the DIII-D divertor during ELMs, inferred from ratios of heat flux to ion flux, are 200-500 eV. Comparisons with TRIM.SP indicate C- >W sputtering dominates W sourcing during ELMs. This is in contrast to JET where ion impact energies are 3-5 keV during ELMs, predicted by the ``free streaming model,'' and D- >W sputtering strongly contributes to W sourcing. Fast measurements of W erosion dynamics during ELMs agree well with TRIM.SP-based sputtering models assuming C/W surface concentrations of 0.5-0.8 and a 2% C2+ ion flux fraction. Core W accumulation and SOL W density measurements made during the DIII-D high-Z tile array mini-campaign correlate with ELM frequency and W source rate. Supported by US DOE under DE-FC02-04ER54698.

  2. sdA in SDSS DR12 are Overwhelmingly Not Extremely Low-Mass (ELM) White Dwarfs

    NASA Astrophysics Data System (ADS)

    Hermes, J. J.; Gänsicke, B. T.; Breedt, E.

    2017-03-01

    In a search for new white dwarfs in DR12 of the Sloan Digital Sky Survey, Kepler et al. 2016 found atmospheric parameters for thousands of objects with effective temperatures below 20,000 K and surface gravities between 5.5 < log g < 6.5. They classified these objects as cool subdwarfs – sdA – and speculated that many may be extremely low-mass (ELM) white dwarfs (helium-core white dwarfs with masses below 0.3 M⊙). We present evidence – using radial velocities, photometric colors, and reduced proper motions – that the vast majority (>99%) of these objects are unlikely to be ELM white dwarfs. Their true identity remains an interesting question.

  3. Investigation of inter-ELM ion heat transport in the H-mode pedestal of ASDEX Upgrade plasmas

    NASA Astrophysics Data System (ADS)

    Viezzer, E.; Fable, E.; Cavedon, M.; Angioni, C.; Dux, R.; Laggner, F. M.; Bernert, M.; Burckhart, A.; McDermott, R. M.; Pütterich, T.; Ryter, F.; Willensdorfer, M.; Wolfrum, E.; the ASDEX Upgrade Team; the EUROfusion MST1 Team

    2017-02-01

    The ion heat transport in the pedestal of H-mode plasmas is investigated in various H-mode discharges with different pedestal ion collisionalities. Interpretive modelling suggests that in all analyzed discharges the ion heat diffusivity coefficient, {χ\\text{i}} , in the pedestal is close to the neoclassical prediction within the experimental uncertainties. The impact of changing the deposition location of the electron cyclotron resonance heating on the ion heat transport has been studied. The effect on the background profiles is small. The pre-ELM (edge localized modes) edge profiles as well as the behaviour of the electron temperature and density, ion temperature and impurity toroidal rotation during the ELM cycle are very similar in discharges with on- and off-axis ECRH heating. No significant deviation of {χ\\text{i}} from neoclassics is observed when changing the ECRH deposition location to the plasma edge.

  4. Increase of turbulence and transport with resonant magnetic perturbations in ELM-suppressed plasmas on DIII-D

    NASA Astrophysics Data System (ADS)

    McKee, G. R.; Yan, Z.; Holland, C.; Buttery, R. J.; Evans, T. E.; Moyer, R. A.; Mordijck, S.; Nazikian, R.; Rhodes, T. L.; Schmitz, O.; Wade, M. R.

    2013-11-01

    Long-wavelength turbulence increases dramatically in the outer regions of DIII-D plasmas with the application of resonant magnetic field perturbations (RMPs) that suppress edge-localized modes (ELMs). Correspondingly, transport increases and global energy confinement decreases in these low-collisionality RMP-ELM suppressed discharges. The core and pedestal density are sharply reduced, while ion and electron temperatures may change only slightly. Low wavenumber density turbulence (k⊥ρi < 1) in the range of 60-300 kHz, measured with beam emission spectroscopy, is modified and generally increases throughout the outer region (0.6 < ρ < 1.0) of the plasma in response to RMPs over a range of q95 values; ELM suppression, in contrast, occurs for a narrower range in q95. Radial magnetic field modulation experiments indicate that these turbulence modifications occur on a time scale of a few milliseconds or less near ρ = 0.85-0.95, significantly faster than transport time-scales and faster than the local pressure gradients and shearing rates evolve at these locations. As the internal coil current is modulated in a square-wave fashion from 3.2 to 4.2 kA, the turbulence magnitude varies in phase by 30% or more, while local density changes by only a few per cent. This dynamical behaviour suggests that the turbulence is directly affected by the RMP, which may partially or largely explain the resulting increased transport and stabilization of the pedestal against peeling-ballooning instabilities that are thought to drive ELMs.

  5. [Coping with leprosy in the Dutch West Indies in the 19th century; opposing but meaningful views from Suriname].

    PubMed

    Menke, Henk; Snelders, Stephen; Pieters, Toine

    2009-01-01

    Leprosy was highly prevalent among African slaves in the Dutch West Indian colony of Suriname. Largely based on observations in Suriname, Dutch physicians described the aetiology of leprosy in terms of'a substrate' to which all sorts of mixtures of infection, heredity and hygiene contributed ('seed and soil'). This explanatory model with multiple options for prevention and treatment left room for different developmental trajectories to control the spread of the disease in the various tropical colonies of the Dutch empire. In Suriname there was a growing worry in the 19th century regarding the spread of leprosy, threatening the health of slaves, settlers and colonial administrators. And this could be harmful to an already weakening plantation economy. This concern prompted the local administration to develop a rigorous policy of strict isolation of leprosy sufferers. This, in turn, intersected with a changing insight in Europe - including the Netherlands - that leprosy was non-contagious. However,'in splendid isolation' in the economically and politically marginal colony Suriname, Dutch physicians like Charles Landre and his son, Charles Louis Drognat Landré, could afford to ignore the European non-contagious approach and continue to support the strict isolation policies. Moreover, they developed a dissident radical explanation of leprosy as a disease caused only by contagion. In the absence of a receptive Dutch audience Drognat Landré published his contagion theory in French and so succeeded in inspiring the Norwegian Hansen, who subsequently discovered the culpable micro-organism. At the same time colonial administrators and physicians in the economically and politically important Dutch colonies in the East Indies adhered to the prevailing European concept and changed policies: the system of isolation was abolished. Given the rather different trajectories of leprosy health policies in the Dutch East and West Indies we point out the importance of a comparative

  6. Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

    PubMed

    Pérez, A; Morelli, L; Cresto, J C; Castaño, E M

    2000-02-01

    Insulin degrading enzyme (IDE) is a metalloprotease that has been involved in amyloid beta peptide (A(beta)) degradation in the brain. We analyzed the ability of human brain soluble fraction to degrade A(beta) analogs 1-40, 1-42 and the Dutch variant 1-40Q at physiological concentrations (1 nM). The rate of synthetic 125I-A(beta) degradation was similar among the A(beta) analogs, as demonstrated by trichloroacetic acid precipitation and SDS-PAGE. A 110 kDa protein, corresponding to the molecular mass of IDE, was affinity labeled with either 125I-insulin, 125I-Abeta 1-40 or 125I-A(beta) 1-42 and both A(beta) degradation and cross-linking were specifically inhibited by an excess of each peptide. Sensitivity to inhibitors was consistent with the reported inhibitor profile of IDE. Taken together, these results suggested that the degradation of A(beta) analogs was due to IDE or a closely related protease. The apparent Km, as determined using partially purified IDE from rat liver, were 2.2 +/- 0.4, 2.0 +/- 0.1 and 2.3 +/- 0.3 microM for A(beta) 1-40, A(beta) 1-42 and A(beta) 1-40Q, respectively. Comparison of IDE activity from seven AD brain cytosolic fractions and six age-matched controls revealed a significant decrease in A(beta) degrading activity in the first group, supporting the hypothesis that a reduced IDE activity may contribute to A(beta) accumulation in the brain.

  7. Government as Electronic Publishers? The Dutch Case.

    ERIC Educational Resources Information Center

    Bouwman, Harry; Nouwens, John

    1999-01-01

    Discussion of the accessibility of government information focuses on how the Dutch government has tried to improve accessibility in six particular cases of electronic publishing. Topics include public-private partnerships, technological barriers of accessibility, outsourcing, and decentralization. (Author/LRW)

  8. Preaccentual Pitch and Speaker Attitude in Dutch.

    ERIC Educational Resources Information Center

    Grabe, Esther; Gussenhoven, Carlos; Haan, Judith; Marsi, Erwin; Post, Brecht Je

    1998-01-01

    Focuses on the communicative significance of the pitch of the initial unstressed syllables in Dutch intonation contours, as may be heard, for instance, on unstressed utterance-initial function words like "Ze zijn" in "Ze zijn klaar (they are ready), or the initial unstressed syllables of utterance-initial polysyllabic words, like…

  9. Delinquent Behavior of Dutch Rural Adolescents

    ERIC Educational Resources Information Center

    Weenink, Don

    2011-01-01

    This article compares Dutch rural and non-rural adolescents' delinquent behavior and examines two social correlates of rural delinquency: communal social control and traditional rural culture. The analyses are based on cross-sectional data, containing 3,797 participants aged 13-18 (48.7% females). The analyses show that rural adolescents are only…

  10. School Leadership and Equity: Dutch Experiences

    ERIC Educational Resources Information Center

    Leeman, Yvonne

    2007-01-01

    There is little empirical evidence describing how school principals respond to the changing socioeconomic position and ethnic identities of the urban population. In this paper such empirical evidence is presented in respect of three primary school leaders in the Dutch cities of Amsterdam and Rotterdam. The schools selected were identified as…

  11. Dutch national rainfallradar project: a unique corporation

    NASA Astrophysics Data System (ADS)

    Schuurmans, Hanneke; Maarten Verbree, Jan; Leijnse, Hidde; van Heeringen, Klaas-Jan; Uijlenhoet, Remko; Bierkens, Mark; van de Giesen, Nick; Gooijer, Jan; van den Houten, Gert

    2013-04-01

    Since January 2013 Dutch watermanagers have access to innovative high-quality rainfall data. This product is innovative because of the following reasons. (i) The product is developed in a 'golden triangle' construction - corporation between government, business and research institutes. (ii) Second the rainfall products are developed according to the open-source GPL license. The initiative comes from a group of water boards in the Netherlands that joined their forces to fund the development of a new rainfall product. Not only data from Dutch radar stations (as is currently done by the Dutch meteorological organization KNMI) is used but also data from radars in Germany and Belgium. After a radarcomposite is made, it is adjusted according to data from raingauges (ground truth). This results in 9 different rainfall products that give for each moment the best rainfall data. This data will be used, depending on the end-user for several applications: (i) forecasts: input for flood early warning systems, (ii) water system analysis: hydrological model input, (iii) optimization: real time control and (iv) investigation of incidents: in case of flooding, who's responsible. The latter is mainly insight in the return period of heavy rainfall events. More info (in Dutch): www.nationaleregenradar.nl

  12. Stabilizing Effect of Resistivity towards ELM-free H-mode Discharge in Lithium-conditioned NSTX

    NASA Astrophysics Data System (ADS)

    Banerjee, Debabrata; Zhu, Ping; Maingi, Rajesh

    2016-10-01

    The stabilizing effect of edge resistivity on the edge localized modes (ELMs) has been recently recovered through analyzing NSTX experimental profiles of Lithium-conditioned ELM-free H-mode discharge. Comparative studies of ELM-free and a reference NSTX ELMy-H mode equilibriums have been performed using both resistive and 2-fluid MHD models implemented in the initial value extended MHD code NIMROD. Our results indicate that in addition to the pedestal profile refinement in electron pressure, the inclusion of enhanced resistivity due to the increase in the effective electric charge number Zeff, which is observed after Lithium-conditioning in experiment, is further required to account for the full stabilization of the low- n edge localized modes. Such a stabilization from the enhanced edge resistivity only becomes effective when the two-fluid diamagnetic and finite-Larmor-radius (FLR) effects are considered in the MHD model. Supported by the National Magnetic Confinement Fusion Program of China under Grant Nos. 2014GB124002 and 2015GB101004, the 100 Talent Program and the President International Fellowship Initiative of the Chinese Academy of Sciences.

  13. Driving toroidally asymmetric current through the tokamak scrape-off layer, Part I: Potential for ELM suppression

    SciTech Connect

    Joseph, I; Cohen, R H; Ryutov, D D

    2009-03-31

    A potential technique for suppressing edge localized magnetohydrodynamic instabilities (ELMs) is theoretically analyzed. Recent experiments have shown that externally generated resonant magnetic perturbations (RMPs) can stabilize ELMs by modifying the density profile [T. E. Evans, et al., Nature Phys. 2, 419 (2006); Y. Liang, et al., Phys. Rev. Lett. 98, 265004 (2007)]. Driving toroidally asymmetric current internally, through the scrape-off layer (SOL) plasma itself, can also generate RMPs that are close to the required threshold for ELM control. The limiting ion saturation current densities can be achieved by producing potential differences on the order of the electron temperature. Although the threshold is uncertain in future devices, if driven coherently though the SOL, the upper limit for the resulting field would exceed the present experimental threshold. This analysis provides the tools required for estimating the magnitude of the coherent SOL current and RMP generated via toroidally asymmetric biasing of the target. Flux expansion increases the RMP near the X-point, while phase interference due to the shearing of field lines near the X-point reduces the amplitude of the effective SOL perturbation and makes the result sensitive to both toroidal mode number n and the radial coherence width of the biasing region. If the limiting current density decays rapidly enough radially, both the width and the amplitude of the current density drawn from the target will be reduced. The RMP can still exceed the present threshold at low n if the radial location and width of the biasing region are optimally chosen.

  14. 3D ELM fluctuation measurements with the new dual array ECE-Imaging diagnostic on ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Classen, Ivo; Vanovac, Branka; Domier, Calvin; Luhmann, Neville; Bogomolov, Anton; Suttrop, Wolfgang; Tobias, Benjamin; ASDEX Upgrade Team

    2015-11-01

    In a major upgrade, the (2D) electron cyclotron emission imaging diagnostic (ECE-Imaging) at ASDEX Upgrade (AUG) has been equipped with a second detector array, and has been successfully commissioned. The two detector arrays observe the plasma through the same vacuum window, both under a slight toroidal angle, to enable quasi-3D measurements of the electron temperature. The system measures a total of 288 channels, in two toroidally separated 2D arrays of approximately 50 cm vertically by 10 cm radially. The toroidal separation between the two poloidal observation planes is about 40 cm, such that the majority of the field lines is observed by both arrays simultaneously, thereby enabling a direct measurement of the 3D properties of plasma instabilities like ELM filaments. The toroidal separation of 40 cm is sufficient for the accurate measurement of both phase differences and transit times of (rotating) plasma structures, enabling a distinction between time varying 2D structures and true 3D structures (not possible with 2D diagnostics). The research will mainly focus on the investigation of the 3D structure of the temperature fluctuations related to edge localized modes (ELMs), in particular precursors and filaments. The first results on ELMs will be reported.

  15. OP-Triplet-ELM: Identification of real and pseudo microRNA precursors using extreme learning machine with optimal features.

    PubMed

    Pian, Cong; Zhang, Jin; Chen, Yuan-Yuan; Chen, Zhi; Li, Qin; Li, Qiang; Zhang, Liang-Yun

    2016-02-01

    MicroRNAs (miRNAs) are a set of short (21-24 nt) non-coding RNAs that play significant regulatory roles in the cells. Triplet-SVM-classifier and MiPred (random forest, RF) can identify the real pre-miRNAs from other hairpin sequences with similar stem-loop (pseudo pre-miRNAs). However, the 32-dimensional local contiguous structure-sequence can induce a great information redundancy. Therefore, it is essential to develop a method to reduce the dimension of feature space. In this paper, we propose optimal features of local contiguous structure-sequences (OP-Triplet). These features can avoid the information redundancy effectively and decrease the dimension of the feature vector from 32 to 8. Meanwhile, a hybrid feature can be formed by combining minimum free energy (MFE) and structural diversity. We also introduce a neural network algorithm called extreme learning machine (ELM). The results show that the specificity ([Formula: see text])and sensitivity ([Formula: see text]) of our method are 92.4% and 91.0%, respectively. Compared with Triplet-SVM-classifier, the total accuracy (ACC) of our ELM method increases by 5%. Compared with MiPred (RF) and miRANN, the total accuracy (ACC) of our ELM method increases nearly by 2%. What is more, our method commendably reduces the dimension of the feature space and the training time.

  16. ELM resolved measurement of fuel recycling on divertor targets in DIII-D

    NASA Astrophysics Data System (ADS)

    Bykov, I.; Hollmann, E. M.; Moyer, R. A.; Watkins, J. G.; Makowski, M.; Lasnier, C. S.; McLean, A.; Wang, H.

    2016-10-01

    Simultaneous measurements of different atomic and molecular contributions are important for determining D recycling from plasma-facing components (PFCs). A splitted filtered imaging of visible-range molecular and atomic emission was applied for the first time for synchronous measurements of Dα (656 nm), D2 Fulcher- α band (600 nm), and CD (430 nm) emissions in the strike point region of the lower divertor in DIII-D. Framing rate up to 1 kHz was sufficient to resolve intra- and inter-ELM phases of H-mode discharges. Radial profiles of atomic (molecular) fluxes of recycled D were deduced using respective S(D)/XB rate coefficients. We present the results of particle flux measurements for a series of shots with varying densities (n/nGW = 0.5-0.8), which affected the degree of the divertor detachment and the balance between individual channels of D recycling from PFCs. Supported by the US DOE under DE-FG02-07ER54917, DE-FG02-04ER54758, DE-FC02-04ER54698, DE-FG03-95ER54309, and DE-FG02-04ER54762.

  17. DT fusion power production in ELM free H modes in JET

    NASA Astrophysics Data System (ADS)

    Rimini, F. G.; JET Team

    1999-11-01

    Experiments in the ELM free hot ion H mode regime have been carried out in DT plasmas in JET. Initial experiments undertaken at constant neutral beam (NB) power (~11 MW) demonstrated that core fuelling was dominated by wall/target recycling rather than NB fuelling and made it possible to arrange an optimum core DT mix by adjusting the DT mix in wall/target, gas and NB. High power experiments at 4.2 MA/3.6 T have successfully and reliably delivered fusion power (Pfus) up to 16.1 MW and plasma stored energy (Wdia) up to 17 MJ. The results are in good agreement with extrapolations, carried out with the TRANSP and JETTO codes, from similar deuterium discharges. Transiently, values of Qtot up to 0.95 +/-0.17 were achieved, consistent with values of nDT(0)τE, diaTi (0) approx 8.7 × 1020 m-3·s·keV+/-20%. The ratio of fusion power to input power, Qin, is in excess of 0.6. There are indications of an isotope effect on the edge pressure pedestal, but no net dependence of global confinement on isotopic plasma composition has been found.

  18. Chlorophyll Catabolites in Fall Leaves of the Wych Elm Tree Present a Novel Glycosylation Motif

    PubMed Central

    Scherl, Mathias; Müller, Thomas; Kreutz, Christoph R.; Huber, Roland G.

    2016-01-01

    Abstract Fall leaves of the common wych elm tree (Ulmus glabra) were studied with respect to chlorophyll catabolites. Over a dozen colorless, non‐fluorescent chlorophyll catabolites (NCCs) and several yellow chlorophyll catabolites (YCCs) were identified tentatively. Three NCC fractions were isolated and their structures were characterized by spectroscopic means. Two of these, Ug‐NCC‐27 and Ug‐NCC‐43, carried a glucopyranosyl appendage. Ug‐NCC‐53, the least polar of these NCCs, was identified as the formal product of an intramolecular esterification of the propionate and primary glucopyranosyl hydroxyl groups of Ug‐NCC‐43. Thus, the glucopyranose moiety and three of the pyrrole units of Ug‐NCC‐53 span a 20‐membered ring, installing a bicyclo[17.3.1]glycoside moiety. This structural motif is unprecedented in heterocyclic natural products, according to a thorough literature search. The remarkable, three‐dimensional bicyclo[17.3.1]glycoside architecture reduces the flexibility of the linear tetrapyrrole. This feature of Ug‐NCC‐53 is intriguing, considering the diverse biological effects of known bicyclo[n.3.1]glycosidic natural products. PMID:27128523

  19. Why are Dutch rheumatologists reluctant to use the COBRA treatment strategy in early rheumatoid arthritis?

    PubMed Central

    van Tuyl, Lilian H D; Plass, Anne Marie C; Lems, Willem F; Voskuyl, Alexandre E; Dijkmans, Ben A C; Boers, Maarten

    2007-01-01

    Background The Combinatietherapie Bij Reumatoide Artritis (COBRA) trial has proved that combination therapy with prednisolone, methotrexate and sulphasalazine is superior to sulphasalazine monotherapy in suppressing disease activity and radiological progression of early rheumatoid arthritis (RA). In addition, 5 years of follow‐up proved that COBRA therapy results in sustained reduction of the rate of radiological progression. Despite this evidence, Dutch rheumatologists seem reluctant to prescribe COBRA therapy. Objective To explore the reasons for the reluctance in Dutch rheumatologists to prescribe COBRA therapy. Methods A short structured questionnaire based on social–psychological theories of behaviour was sent to all Dutch rheumatologists (n = 230). Results The response rate was 50%. COBRA therapy was perceived as both effective and safe, but complex to administer. Furthermore, rheumatologists expressed their concern about the large number of pills that had to be taken, the side effects of high‐dose prednisolone and the low dose of methotrexate. Although the average attitude towards the COBRA therapy was slightly positive (above the neutral point), the majority of responding rheumatologists had a negative intention (below the neutral point) to prescribe COBRA therapy in the near future. Conclusion The reluctance of Dutch rheumatologists to prescribe effective COBRA therapy may be due to perceptions of complexity of the treatment schedule and negative patient‐related consequences of the therapy. PMID:17392349

  20. Do Dutch doctors communicate differently with immigrant patients than with Dutch patients?

    PubMed

    Meeuwesen, Ludwien; Harmsen, Johannes A M; Bernsen, Roos M D; Bruijnzeels, Marc A

    2006-11-01

    The aim of this study was to gain deeper insight into relational aspects of the medical communication pattern in intercultural consultations at GP practices in the Netherlands. We ask whether there are differences in the verbal interaction of Dutch GPs with immigrant and Dutch patients. Data were drawn from 144 adult patient interviews and video observations of consultations between the patients and 31 Dutch GPs. The patient group consisted of 61 non-Western immigrants (Turkish, Moroccan, Surinamese, Antillean, Cape Verdian) and 83 Dutch participants. Affective and instrumental aspects of verbal communication were assessed using Roter's Interaction Analysis System (RIAS). Patients' cultural background was assessed by ethnicity, language proficiency, level of education, religiosity and cultural views (in terms of being more traditional or more modern). Consultations with the non-Western immigrant patients (especially those from Turkey and Morocco) were well over 2 min shorter, and the power distance between GPs and these patients was greater when compared to the Dutch patients. Major differences in verbal interaction were observed on the affective behavior dimensions, but not on the instrumental dimensions. Doctors invested more in trying to understand the immigrant patients, while in the case of Dutch patients they showed more involvement and empathy. Dutch patients seemed to be more assertive in the medical conversation. The differences are discussed in terms of patients' ethnic background, cultural views (e.g. practicing a religion) and linguistic barriers. It is concluded that attention to cultural diversity does matter, as this leads to different medical communication patterns. A two-way strategy is recommended for improving medical communication, with implications for both doctor and patient behavior.

  1. Verb inflection in monolingual Dutch and sequential bilingual Turkish-Dutch children with and without SLI.

    PubMed

    Blom, Elma; de Jong, Jan; Orgassa, Antje; Baker, Anne; Weerman, Fred

    2013-01-01

    Both children with specific language impairment (SLI) and children who acquire a second language (L2) make errors with verb inflection. This overlap between SLI and L2 raises the question if verb inflection can discriminate between L2 children with and without SLI. In this study we addressed this question for Dutch. The secondary goal of the study was to investigate variation in error types and error profiles across groups. Data were collected from 6-8-year-old children with SLI who acquire Dutch as their first language (L1), Dutch L1 children with a typical development (TD), Dutch L2 children with SLI, and Dutch L1 TD children who were on average 2 years younger. An experimental elicitation task was employed that tested use of verb inflection; context (3SG, 3PL) was manipulated and word order and verb type were controlled. Accuracy analyses revealed effects of impairment in both L1 and L2 children with SLI. However, individual variation indicated that there is no specific error profile for SLI. Verb inflection use as measured in our study discriminated fairly well in the L1 group but classification was less accurate in the L2 group. Between-group differences emerged furthermore for certain types of errors, but all groups also showed considerable variation in errors and there was not a specific error profile that distinguished SLI from TD.

  2. Validation of the Model for ELM Suppression with 3D Magnetic Fields Using Low Torque ITER Baseline Scenario Discharges in DIII-D

    NASA Astrophysics Data System (ADS)

    Moyer, R. A.

    2016-10-01

    Suppression of Edge Localized Modes (ELMs) is lost in ITER Baseline Scenario discharges when the torque Tinj and toroidal rotation νϕ are reduced. This is due to a shift in the tearing response deeper into the plasma. ELM suppression is recovered by reducing the normalized plasma pressure βN. In H-mode plasmas, edge turbulence is suppressed in a ``pedestal'' region, leading to large pressure gradients that trigger MHD instabilities (ELMs), causing rapid heat expulsion. 3D magnetic fields are used to drive resonances that limit the pedestal width preventing the ELM. Reducing Tinj changes the νϕ profile such that the drive shifts to a resonance deeper in the plasma, allowing the pedestal to grow again to MHD instability. Reducing βN reduces the edge pressure, which reduces the electron diamagnetic flow and moves the drive to a resonance that is closer to the boundary, recovering suppression. In two-fluid theory, the tearing response occurs at a resonant surface where the electron perpendicular rotation ω (⊥ e) 0 . Linear two-fluid resistive MHD simulations show that the tearing response shifts to a resonance deeper in the plasma when Tinj is reduced. The experimental results confirm that the tearing response occurs for a resonance where ω (⊥ e) 0 , and suggest that the transport which limits the pedestal width is linked to the tearing response, even if any islands are predicted to be small. Although this model describes the differences between ELMing and ELM suppressed H-modes, it doesn't address the transition from ELMs to suppression, because ω (⊥ e) 0 is initially too deep (ψN <= 0.9, q = 3) for the tearing response to limit the pedestal width. Although understanding this transition is important, ITER must apply the RMP in L-mode to avoid the first ELM. These results suggest that manipulation of the edge rotation profile will be important to optimize ELM suppression in future tokamaks. Supported by the US DOE under DE-FG02-07ER54917 and DE-FG02

  3. Mitigation of divertor heat flux by high-frequency ELM pacing with non-fuel pellet injection in DIII-D

    DOE PAGES

    Bortolon, A.; Maingi, R.; Mansfield, D. K.; ...

    2017-03-23

    Experiments have been conducted on DIII-D investigating high repetition rate injection of non-fuel pellets as a tool for pacing Edge Localized Modes (ELMs) and mitigating their transient divertor heat loads. Effective ELM pacing was obtained with injection of Li granules in different H-mode scenarios, at frequencies 3–5 times larger than the natural ELM frequency, with subsequent reduction of strike-point heat flux. However, in scenarios with high pedestal density (~6 × 1019 m–3), the magnitude of granule triggered ELMs shows a broad distribution, in terms of stored energy loss and peak heat flux, challenging the effectiveness of ELM mitigation. Furthermore, transientmore » heat-flux deposition correlated with granule injections was observed far from the strike-points. As a result, field line tracing suggest this phenomenon to be consistent with particle loss into the mid-plane far scrape-off layer, at toroidal location of the granule injection.« less

  4. Budding yeast dma proteins control septin dynamics and the spindle position checkpoint by promoting the recruitment of the Elm1 kinase to the bud neck.

    PubMed

    Merlini, Laura; Fraschini, Roberta; Boettcher, Barbara; Barral, Yves; Lucchini, Giovanna; Piatti, Simonetta

    2012-01-01

    The first step towards cytokinesis in budding yeast is the assembly of a septin ring at the future site of bud emergence. Integrity of this ring is crucial for cytokinesis, proper spindle positioning, and the spindle position checkpoint (SPOC). This checkpoint delays mitotic exit and cytokinesis as long as the anaphase spindle does not properly align with the division axis. SPOC signalling requires the Kin4 protein kinase and the Kin4-regulating Elm1 kinase, which also controls septin dynamics. Here, we show that the two redundant ubiquitin-ligases Dma1 and Dma2 control septin dynamics and the SPOC by promoting the efficient recruitment of Elm1 to the bud neck. Indeed, dma1 dma2 mutant cells show reduced levels of Elm1 at the bud neck and Elm1-dependent activation of Kin4. Artificial recruitment of Elm1 to the bud neck of the same cells is sufficient to re-establish a normal septin ring, proper spindle positioning, and a proficient SPOC response in dma1 dma2 cells. Altogether, our data indicate that septin dynamics and SPOC function are intimately linked and support the idea that integrity of the bud neck is crucial for SPOC signalling.

  5. Edge Stability and Performance of the ELM-Free Quiescent H-Mode and the Quiescent Double Barrier Mode on DIII-D

    SciTech Connect

    West, W P; Burrell, K H; Casper, T A; . Doyle, E J; Snyder, P B; Gohil, P; Lao, L L; Lasnier, C J; Leonard, A W; Nave, M F; Osborne, T H; Thomas, D M; Wang, G; Zeng, L

    2004-12-03

    The quiescent H (QH) mode, an edge localized mode (ELM)-free, high-confinement mode, combines well with an internal transport barrier to form quiescent double barrier (QDB) stationary state, high performance plasmas. The QH-mode edge pedestal pressure is similar to that seen in ELMing phases of the same discharge, with similar global energy confinement. The pedestal density in early ELMing phases of strongly pumped counter injection discharges drops and a transition to QH-mode occurs, leading to lower calculated edge bootstrap current. Plasmas current ramp experiment and ELITE code modeling of edge stability suggest that QH-modes lie near an edge current stability boundary. At high triangularity, QH-mode discharges operate at higher pedestal density and pressure, and have achieved ITER level values of {beta}{sub PED} and {nu}*. The QDB achieves performance of {alpha}{sub N}H{sub 89} {approx} 7 in quasi-stationary conditions for a duration of 10 tE, limited by hardware. Recently we demonstrated stationary state QDB discharges with little change in kinetic and q profiles (q{sub 0} > 1) for 2 s, comparable to ELMing ''hybrid scenarios'', yet without the debilitating effects of ELMs. Plasma profile control tools, including electron cyclotron heating and current drive and neutral beam heating, have been demonstrated to control simultaneously the q profile development, the density peaking, impurity accumulation and plasma beta.

  6. Compilation of hydrologic data, Little Elm Creek, Trinity River Basin, Texas, 1968

    USGS Publications Warehouse

    ,

    1972-01-01

    The U.S. Soil Conservation Service is actively engaged in the installation of flood and soil erosion reducing measures in Texas under the authority of "The Flood Control Act ot 1936 and 1944" and ''Watershed Protection and Flood Prevention Act" (Public Law 566), as amended. In June 1968, the Soil Conservation Service estimated approximately 3,500 structures to be physically and economically feasible for installation in Texas. As of September 30, 1968, 1,271 of these structures had been built. This watershed-development program will have varying but important effects on the surface- and ground-water resources of river basins, especially where a large number of the floodwater-retarding structures are built. Basic hydrologic data are needed to appraise the effects of the structures on water yield and the mode of occurrence of runoff. Hydrologic investigations of these small watersheds were begun by the Geological Survey in 1951 and are now being made in 11 areas (fig. 1). These studies are being made in cooperation with t he Texas Water Development Board, the Soil Conservation Service, the San Antonio River Authority, the city of Dallas, and the Tarrant County Water Control and Improvement District No. 1. The 11 study areas were choson to sample watersheds having different rainfall, topography, geology, and soils. In four of the study areas (Mukewater, North, Little Elm, and Pin Oak Creeks), streamflow and rainfall records were collected prior to construction of the floodwater-retarding structures, thus affording the opportunity for analyses to the conditions before and after" development. Structures have now been built in three of these study areas. A summary of the development of the floodwater-retarding structures on each study area as of September 30, 1968, is shown in table 1.

  7. Nonlinear fluid simulation of particle and heat fluxes during burst of ELMs on DIII-D with BOUT++ code [Fluid Simulation of Particle and Heat Fluxes during Burst of ELMs on DIID with BOUT++ code

    DOE PAGES

    Xia, T. Y.; Xu, X. Q.

    2015-09-01

    In order to study the distribution and evolution of the transient particle and heat fluxes during edge-localized mode (ELM) bursts, a BOUT++ six-field two-fluid model based on the Braginskii equations with non-ideal physics effects is used to simulate pedestal collapse in divertor geometry. We used the profiles from the DIII-D H-mode discharge #144382 with fast target heat flux measurements as the initial conditions for the simulations. Moreover, a flux-limited parallel thermal conduction is used with three values of the flux-limiting coefficientmore » $${{\\alpha}_{j}}$$ , free streaming model with $${{\\alpha}_{j}}=1$$ , sheath-limit with $${{\\alpha}_{j}}=0.05$$ , and one value in between. The studies show that a 20 times increase in $${{\\alpha}_{j}}$$ leads to ~6 times increase in the heat flux amplitude to both the inner and outer targets, and the widths of the fluxes are also expanded. The sheath-limit model of flux-limiting coefficient is found to be the most appropriate one, which shows ELM sizes close to the measurements. The evolution of the density profile during the burst of ELMs of DIII-D discharge #144382 is simulated, and the collapse in width and depth of $${{n}_{\\text{e}}}$$ are reproduced at different time steps. The growing process of the profiles for the heat flux at divertor targets during the burst of ELMs measured by IRTV (infrared television) is also reproduced by this model. The widths of heat fluxes towards targets are a little narrower, and the peak amplitudes are twice the measurements possibly due to the lack of a model of divertor radiation which can effectively reduce the heat fluxes. The magnetic flutter combined with parallel thermal conduction is found to be able to increase the total heat loss by around 33% since the magnetic flutter terms provide the additional conductive heat transport in the radial direction. Finally, the heat flux profile at both the inner and outer targets is obviously broadened by magnetic flutter. The

  8. Nonlinear fluid simulation of particle and heat fluxes during burst of ELMs on DIII-D with BOUT++ code [Fluid Simulation of Particle and Heat Fluxes during Burst of ELMs on DIID with BOUT++ code

    SciTech Connect

    Xia, T. Y.; Xu, X. Q.

    2015-09-01

    In order to study the distribution and evolution of the transient particle and heat fluxes during edge-localized mode (ELM) bursts, a BOUT++ six-field two-fluid model based on the Braginskii equations with non-ideal physics effects is used to simulate pedestal collapse in divertor geometry. We used the profiles from the DIII-D H-mode discharge #144382 with fast target heat flux measurements as the initial conditions for the simulations. Moreover, a flux-limited parallel thermal conduction is used with three values of the flux-limiting coefficient ${{\\alpha}_{j}}$ , free streaming model with ${{\\alpha}_{j}}=1$ , sheath-limit with ${{\\alpha}_{j}}=0.05$ , and one value in between. The studies show that a 20 times increase in ${{\\alpha}_{j}}$ leads to ~6 times increase in the heat flux amplitude to both the inner and outer targets, and the widths of the fluxes are also expanded. The sheath-limit model of flux-limiting coefficient is found to be the most appropriate one, which shows ELM sizes close to the measurements. The evolution of the density profile during the burst of ELMs of DIII-D discharge #144382 is simulated, and the collapse in width and depth of ${{n}_{\\text{e}}}$ are reproduced at different time steps. The growing process of the profiles for the heat flux at divertor targets during the burst of ELMs measured by IRTV (infrared television) is also reproduced by this model. The widths of heat fluxes towards targets are a little narrower, and the peak amplitudes are twice the measurements possibly due to the lack of a model of divertor radiation which can effectively reduce the heat fluxes. The magnetic flutter combined with parallel thermal conduction is found to be able to increase the total heat loss by around 33% since the magnetic flutter terms provide the additional conductive heat transport in the radial direction. Finally, the heat flux profile at both the inner and outer targets is obviously broadened by magnetic flutter. The lobe structures

  9. Effects of rippled fields due to ferritic inserts and ELM mitigation coils on energetic ion losses in a 15 MA inductive scenario in ITER

    NASA Astrophysics Data System (ADS)

    Shinohara, K.; Tani, K.; Oikawa, T.; Putvinski, S.; Schaffer, M.; Loarte, A.

    2012-09-01

    The energetic ion loss has been assessed using the F3D-OFMC code for a 15 MA inductive scenario with Q = 10 and the latest information on the first wall geometry, the implementation of ferritic inserts (FI) and the ELM mitigation/control coils. Alpha particles and NB ions generated by the neutral beam injectors with the injection energy of 1 MeV are well confined and the heat load on the first wall is negligibly small and allowable for the magnetic background by the toroidal field coils and FI. However, an increase in the loss of these energetic ions is observed when the magnetic field by the ELM coils is applied. The increase in the loss fraction is larger for NB ions than for alpha particles under the ELM coil field. The origin of the expelled NB ions is dominantly trapped ions generated in the peripheral region due to a high-density plasma of the 15 MA scenario.

  10. Dutch Venous Ulcer guideline update.

    PubMed

    Maessen-Visch, M Birgitte; de Roos, Kees-Peter

    2014-05-01

    The revised guideline of 2013 is an update of the 2005 guideline "venous leg ulcer". In this special project four separate guidelines (venous leg ulcer, varicose veins, compression therapy and deep venous disorders) were revised and developed simultaneously. A meeting was held including representatives of any organisation involved in venous disease management including patient organizations and health insurance companies. Eighteen clinical questions where defined, and a new strategy was used to accelerate the process. This resulted in two new and two revised guidelines within one year. The guideline committee advises use of the C of the CEAP classification as well as the Venous Clinical Severity Score (VCSS) and a Quality of life (QoL) score in the assessment of clinical signs. These can provide insight into the burden of disease and the effects of treatment as experienced by the patient. A duplex ultrasound should be performed in every patient to establish the underlying aetiology and to evaluate the need for treatment (which is discussed in a separate guideline). The use of the TIME model for describing venous ulcers is recommended. There is no evidence for antiseptic or antibiotic wound care products except for a Cochrane review in which some evidence is presented for cadexomer iodine. Signs of infection are the main reason for the use of oral antibiotics. When the ulcer fails to heal the use of oral aspirin and pentoxifylline can be considered as an adjunct. For the individual patient, the following aspects should be considered: the appearance of the ulcer (amount of exudate) according to the TIME model, the influence of wound care products on moisturising the wound, frequency of changing compression bandages, pain and allergies. The cost of the dressings should also be considered. Education and training of patients t improves compliance with compression therapy but does not influence wound healing rates.

  11. Do Hebrew Electronic Books Differ from Dutch Electronic Books? A Replication of a Dutch Content Analysis

    ERIC Educational Resources Information Center

    Korat, Ofra; Shamir, Adina

    2004-01-01

    This replication study of Hebrew versus Dutch electronic books for young children was based on De Jong & Bus's content analysis, which explored whether e-books are appropriate supports for young children's literacy development. Our criteria for analysing 43 Hebrew e-books for young children included book processing, multimedia in pictures,…

  12. The Dutch Are Missing in the American Curriculum

    ERIC Educational Resources Information Center

    Claunch, Ann

    2009-01-01

    The Dutch are missing in any U.S. history textbook, in the content standards, and in the nationally endorsed curriculum. Outside of New York State history classes, there is almost no mention of the Dutch influence in early 17th-century America. Fleeting references to the Netherlands as a staging area for the Pilgrims' famous "Mayflower"…

  13. The Electrophysiological Manifestation of Dutch Verb Second Violations

    ERIC Educational Resources Information Center

    den Ouden, Dirk-Bart; Bastiaanse, Roelien

    2009-01-01

    We investigated the processing of violations of the verb position in Dutch, in a group of healthy subjects, by measuring event-related potentials (ERPs) through electroencephalography (EEG). In Dutch, the base position of the verb is clause final, but in matrix clauses, the finite verb is in second position, a construction known as "Verb Second".…

  14. National Identification of Dutch Youth: An Exploratory Study

    ERIC Educational Resources Information Center

    Oppenheimer, Louis

    2011-01-01

    246 Dutch participants aged 8, 10, 12, 14, and 16 years were presented with the Strength of Identification Scale (SoIS; Barrett, 2007) and the National Identity scale based on Cultural and Historical achievements (NICH; derived from the NATID, Keillor & Hult, 1999). The study aimed to examine the extent and nature of Dutch children and…

  15. Neural Correlates of Dutch Verb Second in Speech Production

    ERIC Educational Resources Information Center

    den Ouden, Dirk-Bart; Hoogduin, Hans; Stowe, Laurie A.; Bastiaanse, Roelien

    2008-01-01

    Dutch speakers with agrammatic Broca's aphasia are known to have problems with the production of finite verbs in main clauses. This performance pattern has been accounted for in terms of the specific syntactic complexity of the Dutch main clause structure, which requires an extra syntactic operation (Verb Second), relative to the basic…

  16. Reactive oxygen species-provoked mitochondria-dependent cell death during ageing of elm (Ulmus pumila L.) seeds.

    PubMed

    Wang, Yu; Li, Ying; Xue, Hua; Pritchard, Hugh W; Wang, Xiaofeng

    2015-02-01

    Previous studies have shown that controlled deterioration treatment (CDT) induces programmed cell death in elm (Ulmus pumila L.) seeds, which undergo certain fundamental processes that are comparable to apoptosis in animals. In this study, the essential characteristics of mitochondrial physiology in elm seeds during CDT were identified by cellular ultrastructural analysis, whole-body optical imaging, Western blotting and semi-quantitative RT-PCR. The alteration in mitochondrial morphology was an early event during CDT, as indicated by progressive dynamic mitochondrial changes and rupture of the mitochondrial outer membrane; loss of mitochondrial transmembrane potential (Δψ(m)) ensued, and mitochondrial ATP levels decreased. The mitochondrial permeability transition pore inhibitor cyclosporine A effectively suppressed these changes during ageing. The in situ localization of production of reactive oxygen species (ROS), and evaluation of the expression of voltage-dependent anion-selective channel and cyclophilin D indicated that the levels of mitochondrial permeability transition pore components were positively correlated with ROS production, leading to an imbalance of the cellular redox potential and ultimately to programmed cell death. Pre-incubation with ascorbic acid slowed loss of mitochondrial Δψ(m), and decreased the effect of CDT on seed viability. However, there were no significant changes in multiple antioxidant elements or chaperones in the mitochondria during early stages of ageing. Our results indicate that CDT induces dynamic changes in mitochondrial physiology via increased ROS production, ultimately resulting in an irreversible loss of seed viability.

  17. A lognormal distribution of the lengths of terminal twigs on self-similar branches of elm trees.

    PubMed

    Koyama, Kohei; Yamamoto, Ken; Ushio, Masayuki

    2017-01-11

    Lognormal distributions and self-similarity are characteristics associated with a wide range of biological systems. The sequential breakage model has established a link between lognormal distributions and self-similarity and has been used to explain species abundance distributions. To date, however, there has been no similar evidence in studies of multicellular organismal forms. We tested the hypotheses that the distribution of the lengths of terminal stems of Japanese elm trees (Ulmus davidiana), the end products of a self-similar branching process, approaches a lognormal distribution. We measured the length of the stem segments of three elm branches and obtained the following results: (i) each occurrence of branching caused variations or errors in the lengths of the child stems relative to their parent stems; (ii) the branches showed statistical self-similarity; the observed error distributions were similar at all scales within each branch and (iii) the multiplicative effect of these errors generated variations of the lengths of terminal twigs that were well approximated by a lognormal distribution, although some statistically significant deviations from strict lognormality were observed for one branch. Our results provide the first empirical evidence that statistical self-similarity of an organismal form generates a lognormal distribution of organ sizes.

  18. The Dutch Open Telescope on La Palma

    NASA Astrophysics Data System (ADS)

    Rutten, R. J.; Bettonvil, F. C. M.; Hammerschlag, R. H.; Jägers, A. P. L.; Leenaarts, J.; Snik, F.; Sütterlin, P.; Tziotziou, K.; de Wijn, A. G.

    The Dutch Open Telescope (DOT) on La Palma is an innovative solar telescope combining open telescope structure and an open support tower with a multi-wavelength imaging assembly and with synchronous speckle cameras to generate high-resolution movies which sample different layers of the solar atmosphere simultaneously and co-spatially at high resolution over long durations. The DOT test and development phase is nearly concluded. The installation of an advanced speckle processor enables full science utilization including "Open-DOT" time allocation to the international community. Co-pointing with spectropolarimeters at other Canary Island telescopes and with TRACE furnishes valuable Solar-B precursor capabilities.

  19. Characterisation of the deuterium recycling at the W divertor target plates in JET during steady-state plasma conditions and ELMs

    NASA Astrophysics Data System (ADS)

    Brezinsek, S.; Wiesen, S.; Harting, D.; Guillemaut, C.; Webster, A. J.; Heinola, K.; Meigs, A. G.; Rack, M.; Gao, Y.; Sergienko, G.; Philipps, V.; Stamp, M. F.; Jachmich, S.; Contributors, JET

    2016-02-01

    Experiments in the JET tokamak equipped with the ITER-like wall (ILW) revealed that the inner and outer target plate at the location of the strike points represent after one year of operation intact tungsten (W) surfaces without any beryllium (Be) surface coverage. The dynamics of near-surface retention, implantation, desorption and recycling of deuterium (D) in the divertor of plasma discharges are determined by W target plates. As the W plasma-facing components (PFCs) are not actively cooled, the surface temperature (T surface) is increasing with plasma exposure, varying the balance between these processes in addition to the impinging deuteron fluxes and energies. The dynamic behaviour on a slow time scale of seconds was quantified in a series of identical L-mode discharges (JET Pulse Number (JPN) \\# 81938-73) by intra-shot gas analysis providing the reduction of deuterium retention in W PFCs by 1/3 at a base temperature (T base) range at the outer target plate between 65 °C and 150 °C equivalent to a T surface span of 150 °C and 420 °C. The associated recycling and molecular D desorption during the discharge varies only at lowest temperatures moderately, whereas desorption between discharges rises significantly with increasing T base. The retention measurements represent the sum of inner and outer divertor interaction at comparable T surface. The dynamic behaviour on a fast time scale of ms was studied in a series of identical H-mode discharges (JPN \\#83623-83974) and coherent edge-localized mode (ELM) averaging. High energetic ELMs of about 3 keV are impacting on the W PFCs with fluxes of 3× {10}23 {{{D}}}+ {{{s}}}-1{{{m}}}-2 which is about four times higher than inter-ELM ion fluxes with an impact energy of about E im = 200 eV. This intra-ELM ion flux is associated with a high heat flux of about 60 MW m-2 to the outer target plate which causes T surface rise by Δ T = 100 K per ELM covering finally the range between 160 °C and 1400 °C during the flat

  20. A century of Dutch neurology.

    PubMed

    Koehler, P J; Bruyn, G W; Moffie, D

    1998-12-01

    The Netherlands Society of Neurology evolved from the Society of Psychiatry founded in 1871. The name was changed into Netherlands Society of Psychiatry and Neurology (NSPN) in 1897. In the same year, the word neurology was also added to the name of the journal. The Society steadily blossomed, but in 1909 the first signs of dissatisfaction occurred: the Amsterdam Neurologists Society was founded. A few split-offs would follow. The number of members of the NSPN increased from 205 in 1920 to 585 in 1960. In the early 1960s, the Society was reorganised and would consist of two sections, one for psychiatry and one for neurology. However, this would not last, as a full separation was established in 1974. For several reasons, the name of the journal was changed four times until it assumed its present name in 1974. The 100th volume of CNN was not published, as expected. in 1996, but in 1998, because of two skipped publication years, one during WWII and another in the 1970s. During the last decades of the nineteenth century, teaching of neurology was mostly given within the frame of psychiatry, following the German tradition of 'brainpsychiatry' (organic or biologic psychiatry). The first official chair of psychiatry was founded at Utrecht, 1893 (Winkler). In Amsterdam, private teachers such as Delprat taught 'electro-therapy and nervous diseases' since the 1880s. The first extraordinary chair of neurology and electrotherapy was founded for his successor, Wertheim Salomonson in 1899. The first university clinic for psychiatry and neurology started at the Amsterdam Municipal University, when Winkler became professor of psychiatry and neurology in Amsterdam in 1896. Around the turn of the century, chairs of psychiatry and neurology were also founded in Groningen and Leiden. Separate chairs for neurology and psychiatry appeared in Amsterdam in 1923 and in Utrecht in 1936. Following an initiative of Brouwer, the first neurological university clinic opened its doors in

  1. Sustainable Phoenix: Lessons from the Dutch Model

    NASA Astrophysics Data System (ADS)

    Lara, Jesus J.

    In only fifty years, the Phoenix metropolitan area has expanded from a small desert town into one of the largest urban areas in the United States. Today, it has one of the fastest rates of growth in the nation with an annual rate of 4.5%. This area has grown during a period in urban development that largely ignored local topography, climate, culture, and history. The result has been a sprawling metropolitan area with an ever increasing ecological footprint and a standardized urban design and infrastructure that works against its environmental setting rather than with it. Currently, the city of Phoenix is going through a process of urban revitalization with an increasing demand for urban living and commerce. This research explores sustainable urban design and its potential applications in the metropolitan Phoenix area through an investigation of the Dutch model. The Dutch have successfully dealt with sustainable urban design approaches and their practices represent an unusual learning opportunity for Phoenix. The Netherlands' experience suggests three strategies/themes for rendering Phoenix a more sustainable urban form. These include the strategic planning and development of urban extensions, compact infill, and modernizing infrastructure.

  2. Cancer incidence in Dutch Balkan veterans.

    PubMed

    Bogers, Rik P; van Leeuwen, Flora E; Grievink, Linda; Schouten, Leo J; Kiemeney, Lambertus A L M; Schram-Bijkerk, Dieneke

    2013-10-01

    Suspicion has been raised about an increased cancer risk among Balkan veterans because of alleged exposure to depleted uranium. The authors conducted a historical cohort study to examine cancer incidence among Dutch Balkan veterans. Male military personnel (n=18,175, median follow-up 11 years) of the Army and Military Police who had been deployed to the Balkan region (1993-2001) was compared with their peers not deployed to the Balkans (n=135,355, median follow-up 15 years) and with the general Dutch population of comparable age and sex. The incidence of all cancers and 4 main cancer subgroups was studied in the period 1993-2008. The cancer incidence rate among Balkan deployed military men was 17% lower than among non-Balkan deployed military men (hazard ratio 0.83 (95% confidence interval 0.69, 1.00)). For the 4 main cancer subgroups, hazard ratios were statistically non-significantly below 1. Also compared to the general population cancer rates were lower in Balkan deployed personnel (standardised incidence rate ratio (SIR) 0.85 (0.73, 0.99). The SIR for leukaemia was 0.63 (0.20, 1.46). The authors conclude that earlier suggestions of increased cancer risks among veterans are not supported by empirical data. The lower risk of cancer might be explained by the 'healthy warrior effect'.

  3. Media Literacy and Attitude Change: Assessing the Effectiveness of Media Literacy Training on Children's Responses to Persuasive Messages within the ELM.

    ERIC Educational Resources Information Center

    Yates, Bradford L.

    This study adds to the small but growing body of literature that examines the effectiveness of media literacy training on children's responses to persuasive messages. Within the framework of the Elaboration Likelihood Model (ELM) of persuasion, this research investigates whether media literacy training is a moderating variable in the persuasion…

  4. ICGA-PSO-ELM approach for accurate multiclass cancer classification resulting in reduced gene sets in which genes encoding secreted proteins are highly represented.

    PubMed

    Saraswathi, Saras; Sundaram, Suresh; Sundararajan, Narasimhan; Zimmermann, Michael; Nilsen-Hamilton, Marit

    2011-01-01

    A combination of Integer-Coded Genetic Algorithm (ICGA) and Particle Swarm Optimization (PSO), coupled with the neural-network-based Extreme Learning Machine (ELM), is used for gene selection and cancer classification. ICGA is used with PSO-ELM to select an optimal set of genes, which is then used to build a classifier to develop an algorithm (ICGA_PSO_ELM) that can handle sparse data and sample imbalance. We evaluate the performance of ICGA-PSO-ELM and compare our results with existing methods in the literature. An investigation into the functions of the selected genes, using a systems biology approach, revealed that many of the identified genes are involved in cell signaling and proliferation. An analysis of these gene sets shows a larger representation of genes that encode secreted proteins than found in randomly selected gene sets. Secreted proteins constitute a major means by which cells interact with their surroundings. Mounting biological evidence has identified the tumor microenvironment as a critical factor that determines tumor survival and growth. Thus, the genes identified by this study that encode secreted proteins might provide important insights to the nature of the critical biological features in the microenvironment of each tumor type that allow these cells to thrive and proliferate.

  5. Effect of n = 3 perturbation field amplitudes below the ELM triggering threshold on edge and SOL transport in NSTX

    SciTech Connect

    J. M. Canik; Lore, J. D.; Ahn, J. -W.; Bortolon, A.; Fredrickson, E. D.; Jaworski, M. A.; Kramer, G. J.; Maingi, R.; McLean, A. G.; Scotti, F.; Soukhanovskii, V. A.; Tritz, K.

    2013-01-12

    Here, the pulsed application of n = 3 magnetic perturbation fields with amplitudes below that which triggers ELMs results in distinct, transient responses observable on several edge and divertor diagnostics in NSTX. We refer to these responses as Sub-Threshold Edge Perturbations (STEPs). An analysis of edge measurements suggests that STEPs result in increased transport in the plasma edge and scrape-off layer, which leads to augmentation of the intrinsic strike point splitting due to error fields, i.e., an intensification of the helical divertor footprint flux pattern. These effects are much smaller in magnitude than those of triggered ELMs, and are observed for the duration of the field perturbation measured internal to the vacuum vessel. In addition, STEPs are correlated with changes to the MHD activity, along with transient reductions in the neutron production rate. Ideally the STEPs could be used to provide density control and prevent impurity accumulation, in the same manner that on-demand ELM triggering is used on NSTX, without the impulsive divertor fluxes and potential for damage to plasma facing components associated with ELMs.

  6. Extending glacial refugia for a European tree: genetic markers show that Iberian populations of white elm are native relicts and not introductions

    PubMed Central

    Fuentes-Utrilla, P; Venturas, M; Hollingsworth, P M; Squirrell, J; Collada, C; Stone, G N; Gil, L

    2014-01-01

    Conservation policies usually focus on in situ protection of native populations, a priority that requires accurate assessment of population status. Distinction between native and introduced status can be particularly difficult (and at the same time, is most important) for species whose natural habitat has become both rare and highly fragmented. Here, we address the status of the white elm (Ulmus laevis Pallas), a European riparian tree species whose populations have been fragmented by human activity and is protected wherever it is considered native. Small populations of this species are located in Iberia, where they are unprotected because they are considered introductions due to their rarity. However, Iberia and neighbouring regions in southwestern France have been shown to support discrete glacial refuge populations of many European trees, and the possibility remains that Iberian white elms are native relicts. We used chloroplast RFLPs and nuclear microsatellites to establish the relationship between populations in Iberia and the Central European core distribution. Bayesian approaches revealed significant spatial structure across populations. Those in Iberia and southwestern France shared alleles absent from Central Europe, and showed spatial population structure within Iberia common in recognized native taxa. Iberian populations show a demographic signature of ancient population bottlenecks, while those in Central European show a signature of recent population bottlenecks. These patterns are not consistent with historical introduction of white elm to Iberia, and instead strongly support native status, arguing for immediate implementation of conservation measures for white elm populations in Spain and contiguous areas of southern France. PMID:24022495

  7. Experimental investigation of vapor shielding effects induced by ELM-like pulsed plasma loads using the double plasma gun device

    NASA Astrophysics Data System (ADS)

    Sakuma, I.; Kikuchi, Y.; Kitagawa, Y.; Asai, Y.; Onishi, K.; Fukumoto, N.; Nagata, M.

    2015-08-01

    We have developed a unique experimental device of so-called double plasma gun, which consists of two magnetized coaxial plasma gun (MCPG) devices, in order to clarify effects of vapor shielding on material erosion due to transient events in magnetically confined fusion devices. Two ELM-like pulsed plasmas produced by the two MCPG devices were injected into a target chamber with a variable time difference. For generating ablated plasmas in front of a target material, an aluminum foil sample in the target chamber was exposed to a pulsed plasma produced by the 1st MCPG device. The 2nd pulsed plasma was produced with a time delay of 70 μs. It was found that a surface absorbed energy measured by a calorimeter was reduced to ∼66% of that without the Al foil sample. Thus, the reduction of the incoming plasma energy by the vapor shielding effect was successfully demonstrated in the present experiment.

  8. Non-Ideal ELM Stability and Non-Axisymmetric Field Penetration Calculations with M3D-C1

    NASA Astrophysics Data System (ADS)

    Ferraro, N. M.; Chu, M. S.; Snyder, P. B.; Jardin, S. C.; Luo, X.

    2009-11-01

    Numerical studies of ELM stability and non-axisymmetric field penetration in diverted DIII-D and NSTX equilibria are presented, with resistive and finite Larmor radius effects included. These results are obtained with the nonlinear two-fluid code M3D-C1, which has recently been extended to allow linear non-axisymmetric calculations. Benchmarks of M3D-C1 with ideal codes ELITE and GATO show good agreement for the linear stability of peeling-ballooning modes in the ideal limit. New calculations of the resistive stability of ideally stable DIII-D equilibria are presented. M3D-C1 has also been used to calculate the linear response to non-axisymmetric external fields; these calculations are benchmarked with Surfmn and MARS-F. New numerical methods implemented in M3D-C1 are presented, including the treatment of boundary conditions with C^1 elements in a non-rectangular mesh.

  9. Long-lived impurity-ion snakes in the EAST ELM-free H-mode Sawtoothing plasma

    NASA Astrophysics Data System (ADS)

    Ma, Tianpeng; Xu, Liqing; Hu, Liqun

    2015-06-01

    Two types of long-lived impurity-ion snakes (LLSs) including the ideal-like kink mode which damps before the large sawtooth crash, termed sawtooth-free LLSs (SF-LLSs) and complex LLSs (C-LLSs), which coexist with compound sawtooth and final damping after sawtooth crash were observed in EAST ELM-free H-mode sawtoothing plasma. These LLSs have an m = 1 structure, accompanied by several harmonic modes (m = 2, m = 3...). There is a slight frequency-chirping behavior of the LLS. Similar with the typical sawtooth crash phase, a large crescent-shaped helical island-like structure in the core region of the C-LLSs was visible after the major crash of the coexisting compound sawtooth. The strong coupling of the C-LLSs and the 2/1 tearing mode (TM) can trigger a neo-classical tearing mode (NTM) due to a forced magnetic reconnection.

  10. [Prevalence of Tritrichomonas foetus among Dutch cats].

    PubMed

    van Doorn, D C K; de Bruin, M J; Jorritsma, R A; Ploeger, H W; Schoormans, A

    2009-09-01

    Prevalence of Tritrichomonas foetus among Dutch cats The aim of this study was to determine the prevalence of and risk factors for, Tritrichomonas foetus among cats in the Netherlands. A total of 154 faecal samples were collected from three groups of cats: cats with diarrhoea (n=53), cattery cats (n=47), and healthy pet cats (n=54). Faecal samples were examined with a T. foetus specific real-time PCR. All PCR-positive samples were run on gel electrophoresis for definitive diagnosis. The prevalence of T. foetus was 2% among cats with diarrhoea and 4% among cattery cats; T. foetus was not prevalent among pet cats (none of the samples tested positive). Questionnaires had been distributed to cat and cattery owners to determine risk factors for T. foetus, but the low prevalence precluded statistical analysis of the questionnaire results.

  11. Subacute ruminal acidosis in Dutch dairy herds.

    PubMed

    Kleen, J L; Hooijer, G A; Rehage, J; Noordhuizen, J P T M

    2009-05-30

    The prevalence of subacute ruminal acidosis (SARA) was determined in 197 dairy cows in 18 herds in the Dutch province of Friesland. Samples of rumen fluid were taken by rumenocentesis from between five and 19 animals on each farm and the pH of each sample was determined. The body condition of 139 of the cows was scored approximately three weeks before they calved and three weeks after they calved. The overall prevalence of SARA was 13.8 per cent, and the prevalence on individual farms ranged between 0 per cent (on seven of the farms) and 38 per cent (on one farm). The stage of lactation did not influence the prevalence of SARA but the cows with the condition lost more body condition over the calving period.

  12. Development of a Dutch Drainpipe exposure scenario

    NASA Astrophysics Data System (ADS)

    Tiktak, Aaldrik; Boesten, Jos; van der Linden, Ton

    2010-05-01

    In the new Dutch pesticide authorisation procedure, the leaching of pesticides to surface waters will be evaluated. The 90th percentile of the peak concentrations in all Dutch ditches will be used for the exposure assessment of aquatic organisms The peak concentration in surface waters is primarily affected by fast transfer routes (amongst others by macropores). For this reason, we developed a macropore version of the pesticide leaching model PEARL. The macropore version of PEARL describes transport of pesticides through the soil matrix and through two preferential flow domains, i.e. a bypass domain and an internal catchment domain. The drainpipe exposure assessment will be done for a single field site. We selected the Andelst field experiment (Scorza Júnior et al., 2004) for this purpose, because at this site sufficient data is available to parameterise and test the model. To assess the effect of weather variability on drainpipe concentration, the model is run for a 20-years period. Hydrological boundary conditions for the 20-years period were taken from nearby weather stations and ground water observation wells. Application of PEARL to this field site showed that the model adequately describes the peak concentration and the later decline of the concentration for two different pesticides. The exposure assessment at the Andelst field site results in 20 annual peak concentrations, that need to be compared with the 90th percentile of the peak concentration in all Dutch ditches, so we performed simulations with a spatially-distributed version of PEARL. This assessment resulted in 20 times n concentrations, with n the number of locations. A contour diagram was used to assess which weather year corresponds with the 90th percentile of all 20 times n peak concentrations. The X-coordinate in the contour diagram corresponds with the percentile of the cumulative distribution of the predicted concentrations due to spatial variability that is obtained for a median weather

  13. The art of governance of Dutch hospitals.

    PubMed

    Hoek, H

    1999-01-01

    Hospitals in The Netherlands are governed by two boards: The Board of Directors, the legal representative of the hospital, responsible for strategic and operational business activities; and the Supervisory Board, made up of co-opted volunteers and responsible for checking and approving of the major decisions of the Board of Directors. The question which arises is whether the system of governance is able to function appropriately and guarantee enough concern about general health problems, moral and ethical questions and the interest of the patients. This paper investigate the successes and shortfalls of such a system of governance in Dutch hospitals. The results and conclusions determine that although copied from the corporate governance model, it does not function well in an environment where the influence of patients and the inhabitants of the region are of great importance and shareholders do not exist.

  14. The Dutch school of malaria research.

    PubMed

    Verhave, J P

    1987-01-01

    An epidemic of tertian malaria in some coastal areas of The Netherlands resulted in the setting up of official measures in 1920. A scientific and a propaganda commission were charged with control. Efforts were made to reduce mosquito populations by adult and larval spraying. After the discovery that infected mosquitoes were to be found only inside houses, control operations were focussed against adult mosquitoes. Some later discoveries resulted in a more effective control. a) Spraying ditches with Paris green did not prevent adult mosquitoes from entering the control area. b) Anopheles maculipennis turned out to be a complex of species, with A. atroparvus as the vector. The latter preferred brackish water and did not go into full hibernation. The closing of the Zuyder Sea and the expected desalinization gave hope for less suitable conditions for the vector. c) Plasmodium vivax normally had an incubation period of 8 months. d) Pyrethrum was an effective but short-lasting insecticide. e) Healthy parasite carriers could infect mosquitoes. This knowledge was applied through an extensive system of investigation, including spleen examination of schoolchildren. Suspected houses were sprayed bimonthly from August to November, during which period infected mosquitoes were likely to be present. This system worked extremely well, and during the next epidemic from 1943 to 1947 the thus treated towns remained virtually free of malaria! DDT became available and was either sprayed in suspected houses as before, or through wide-spread coverage of all houses. The epidemic subsided whatever method employed and not only due to the use of DDT. The number of cases even went down to the point of no return and the last case of Dutch malaria was recorded in 1959. The wealth of experience on house-spray control, parasite and mosquito biology and experimental malaria of the Dutch malariologists has had its impact on the international bodies engaged in the battle against malaria.

  15. Interior view of addition pharmacy showing dutch door and security ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of addition pharmacy showing dutch door and security ceiling grate, facing north. - Albrook Air Force Station, Dispensary, East side of Canfield Avenue, Balboa, Former Panama Canal Zone, CZ

  16. Emerson Parcel of Dutch Slough Tidal Marsh Restoration Project

    EPA Pesticide Factsheets

    Information about the SFBWQP Emerson Parcel of Dutch Slough Tidal Marsh Restoration Project, part of an EPA competitive grant program to improve SF Bay water quality focused on restoring impaired waters and enhancing aquatic resources.

  17. [The Dutch Health Council report on screening for Chlamydia: too reserved].

    PubMed

    Dekker, J H

    2005-04-16

    The prevalence of sexually transmitted diseases (STDs) increased in the Netherlands in the years 2000-2003. A recent population-based study showed that Chlamydia infections were a problem in urbanised areas; prevalence in rural areas was low. In 2004, the Dutch Health Council advised against a national screening programme for Chlamydia. However, the newest figures on the distribution of Chlamydia infections suggest that screening in large cities might be cost-effective. Much can be learned from the screening programme in the United Kingdom.

  18. Preboreal climate oscillations in Europe: Wiggle-match dating and synthesis of Dutch high-resolution multi-proxy records

    NASA Astrophysics Data System (ADS)

    Bos, Johanna A. A.; van Geel, Bas; van der Plicht, Johannes; Bohncke, Sjoerd J. P.

    2007-08-01

    In order to compare environmental and inferred climatic change during the Preboreal in The Netherlands, five terrestrial records were analysed. Detailed multi-proxy analyses including microfossils (e.g., pollen, spores, algae, and fungal spores), macroremains (e.g., seeds, fruits, wood, mosses, etc.), and loss on ignition measurements were carried out with high temporal resolution. To link the five Preboreal records, accurate chronologies were produced by AMS 14C wiggle-match dating. The Dutch records show that following the Lateglacial/Holocene climate warming, birch woodlands expanded between 11,530 and 11,500 cal BP during the Friesland Phase of the Preboreal. After the Friesland Phase, two distinct climatic shifts could be inferred: (1) around 11,430-11,350 cal BP the expansion of birch forests was interrupted by a dry continental phase with open grassland vegetation, the Rammelbeek Phase. This phase was coeval with the coldest part of the Preboreal oscillation (PBO) as observed in the δ 18O record of the Greenland ice-core records and has been attributed to a large meltwater flux that resulted in a temporary decrease of the thermohaline circulation in the North Atlantic. (2) At the start of the Late Preboreal, between 11,270 and 11,210 cal BP, a sudden shift to a more humid climate occurred and birch forests expanded again. A simultaneous increase in the cosmogenic nuclides 14C and 10Be suggests that these changes in climate and vegetation were forced by a sudden decline in solar activity. Expansion of pine occurred during the later part of the Late Preboreal. At the onset of the Boreal, between 10,770 and 10,700 cal BP, dense woodlands with hazel, oak, elm and pine started to develop in The Netherlands.

  19. Translation, cross-cultural adaptation, and validation of the Mouth Handicap in Systemic Sclerosis questionnaire (MHISS) into the Dutch language.

    PubMed

    Schouffoer, A A; Strijbos, E; Schuerwegh, A J M; Mouthon, L; Vliet Vlieland, T P M

    2013-11-01

    The Mouth Handicap in Systemic Sclerosis (MHISS) is a French-generic questionnaire evaluating mouth-opening restriction, dryness, and esthetic concerns. The aim of this study was to translate and adapt the MHISS questionnaire into the Dutch language and evaluate its psychometric properties. The MHISS was translated according to international guidelines, field-tested among 16 systemic sclerosis (SSc) patients, and adapted. Subsequently, the Dutch MHISS was administered to 52 SSc patients visiting the outpatient or day patient clinic of a university hospital and readministered after 2 weeks. Internal consistency was tested by computing Cronbach's alpha. Test-retest reliability was determined by computing the intraclass correlation coefficient (ICC) and validity by determining associations with measures of overall functioning (Health Assessment Questionnaire (HAQ)), maximum mouth opening (MMO, in millimeter), subjective xerostomia (visual analog scale), and objective xerostomia (Saxon test). Patients had mean ± standard deviation (SD) age and disease duration of 55 ± 21 and 7.2 ± 7.3 years. Twenty-seven (52 %) patients had diffuse cutaneous SSc. The mean Dutch MHISS score was 17.5 (SD 10.0) with Cronbach's alpha being 0.862. Dutch MHISS scores differed significantly between patients with high and low disability levels (HAQ, MMO, and subjective and objective xerostomia divided according to the median; paired t test). Spearman rank correlations with HAQ (r = 0.599, p = 0.000), MMO (r = -0.518, p = 0.000), and subjective xerostomia (r = 0.536, p = 0.000) were moderate; correlation with objective xerostomia did not reach statistical significance. The ICC was 0.94. The Dutch version of the MHISS demonstrated good psychometric properties and is useful in assessing mouth disability in SSc patients.

  20. Persistent Identifiers for Dutch cultural heritage institutions

    NASA Astrophysics Data System (ADS)

    Ras, Marcel; Kruithof, Gijsbert

    2016-04-01

    Over the past years, more and more collections belonging to archives, libraries, media, museums, and knowledge institutes are being digitised and made available online. These are exciting times for ALM institutions. They are realising that, in the information society, their collections are goldmines. Unfortunately most heritage institutions in the Netherlands do not yet meet the basic preconditions for long-term availability of their collections. The digital objects often have no long lasting fixed reference yet. URL's and web addresses change. Some digital objects that were referenced in Europeana and other portals can no longer be found. References in scientific articles have a very short life span, which is damaging for scholarly research. In 2015, the Dutch Digital Heritage Network (NDE) has started a two-year work program to co-ordinate existing initiatives in order to improve the (long-term) accessibility of the Dutch digital heritage for a wide range of users, anytime, anyplace. The Digital Heritage Network is a partnership established on the initiative of the Ministry of Education, Culture and Science. The members of the NDE are large, national institutions that strive to professionally preserve and manage digital data, e.g. the National Library, The Netherlands Institute for Sound and Vision, the Netherlands Cultural Heritage Agency, the Royal Netherlands Academy of Arts and Sciences, the National Archive of the Netherlands and the DEN Foundation, and a growing number of associations and individuals both within and outside the heritage sector. By means of three work programmes the goals of the Network should be accomplished and improve the visibility, the usability and the sustainability of digital heritage. Each programme contains of a set of projects. Within the sustainability program a project on creating a model for persistent identifiers is taking place. The main goals of the project are (1) raise awareness among cultural heritage institutions on the

  1. [Dutch computer domestication, 1975-1990].

    PubMed

    Veraart, Frank

    2008-01-01

    A computer seems an indispensable tool among twenty-first century households. Computers however, did not come as manna from heaven. The domestication and appropriation of computers in Dutch households was a result of activities by various intermediary actors. Computers became household commodities only gradually. Technophile computer hobbyists imported the first computers into the Netherlands from the USA, and started small businesses from 1975 onwards. They developed a social network in which computer technology was made available for use by individuals. This network extended itself via shops, clubs, magazines, and other means of acquiring and exchanging computer hard- and software. Hobbyist culture established the software-copying habits of private computer users as well as their ambivalence to commercial software. They also made the computer into a game machine. Under the impulse of a national policy that aimed at transforming society into an 'Information Society', clubs and other actors extended their activities and tailored them to this new agenda. Hobby clubs presented themselves as consumer organizations and transformed into intermediary actors that filled the gap between suppliers and a growing group of users. They worked hard to give meaning to (proper) use of computers. A second impulse to the increasing use of computers in the household came from so-called 'private-PC' projects in the late 1980s. In these projects employers financially aided employees in purchasing their own private PCs'. The initially important intermediary actors such as hobby clubs lost control and the agenda for personal computers was shifted to interoperability with office equipment. IBM compatible PC's flooded the households. In the household the new equipment blended with the established uses, such as gaming. The copying habits together with the PC standard created a risky combination in which computer viruses could spread easily. New roles arose for intermediary actors in guiding

  2. Changing faces in virology: the dutch shift from oncogenic to oncolytic viruses.

    PubMed

    Belcaid, Zineb; Lamfers, Martine L M; van Beusechem, Victor W; Hoeben, Rob C

    2014-10-01

    Viruses have two opposing faces. On the one hand, they can cause harm and disease. A virus may manifest directly as a contagious disease with a clinical pathology of varying significance. A viral infection can also have delayed consequences, and in rare cases may cause cellular transformation and cancer. On the other hand, viruses may provide hope: hope for an efficacious treatment of serious disease. Examples of the latter are the use of viruses as a vaccine, as transfer vector for therapeutic genes in a gene therapy setting, or, more directly, as therapeutic anticancer agent in an oncolytic-virus therapy setting. Already there is evidence for antitumor activity of oncolytic viruses. The antitumor efficacy seems linked to their capacity to induce a tumor-directed immune response. Here, we will provide an overview on the development of oncolytic viruses and their clinical evaluation from the Dutch perspective.

  3. Cadaver brains and excesses in Baccho and Venere: dementia paralytica in Dutch psychiatry (1870-1920).

    PubMed

    Slijkhuis, Jessica; Oosterhuis, Harry

    2014-07-01

    This article explores the approach of dementia paralytica by psychiatrists in the Netherlands between 1870 and 1920 against the background of international developments. The psychiatric interpretation of this mental and neurological disorder varied depending on the institutional and social context in which it was examined, treated, and discussed by physicians. Psychiatric diagnoses and understandings of this disease had in part a social-cultural basis and can be best explained against the backdrop of the establishment of psychiatry as a medical specialty and the specific efforts of Dutch psychiatrists to expand their professional domain. After addressing dementia paralytica as a disease and why it drew so much attention in the late nineteenth and early twentieth century, this essay discusses how psychiatrists understood dementia paralytica in asylum practice in terms of diagnosis, care, and treatment. Next we consider their pathological-anatomical study of the physical causes of the disease and the public debate on its prevalence and causes.

  4. Inter-ELM evolution of the pedestal structures in type-I ELMy H-mode plasmas with LHW and NBI heating on EAST

    NASA Astrophysics Data System (ADS)

    Han, X.; Zang, Q.; Xiao, S.; Wang, T.; Hu, A.; Tian, B.; Li, D.; Zhou, H.; Zhao, J.; Hsieh, C.; Li, M.; Yan, N.; Gong, X.; Hu, L.; Xu, G.; Gao, X.; the EAST Team

    2017-04-01

    The evolution characteristics of type-I ELMy high-confinement mode pedestal are examined in EAST based on the recently developed Thomson scattering system. The influence of the plasma current on pedestal evolvement has been confirmed experimentally. In the higher I p case (500 kA) the pedestal height shows an increase trend until the onset of next ELM and in the lower I p cases (300 and 400 kA), however, this buildup saturates at the first ∼30% of the ELM cycle. In contrast, the width increases only during the first ∼70% of the ELM cycle and then keeps almost stable in three I p cases, but resulting in different widening size of ∼1.5, 1 and 0.5 cm for 300, 400 and 500 kA respectively. Experimental results show that the pedestal pressure width has good correlation with poloidal beta as {{{Δ }}}{{p}{{e}},\\psi }=0.16\\sqrt{{{β }}{{p}{{o}}{{l}}}}, where the fitting coefficient 0.16 is not changed with different plasma currents but a little larger than that of other machines. For each current level, the pedestal density increases while the pedestal temperature decreases. But with increasing {I}{{p}} platforms, the pedestal height prior to the ELM onset shows a near quadratic (within error bars) increase. Experimental measurements demonstrate that the decrease of {{Δ }}{W}{{E}{{L}}{{M}}} with increasing {ν }{{p}{{e}}{{d}}}* comes mostly from the reduction of the plasma temperature drop, while the pedestal density height keeps relatively stable. Additional injection of LHW has been proved to modify the pedestal structure which should be responsible for the remaining scatter of the experimental data.

  5. QUIESCENT H-MODE, AN ELM-FREE HIGH-CONFINEMENT MODE ON DIII-D WITH POTENTIAL FOR STATIONARY STATE OPERATION

    SciTech Connect

    WEST,WP; BURRELL,KH; deGRASSIE,JS; DOYLE,EJ; GREENFIELD,CM; LASNIER,CJ; SNYDER,PB; ZENG,L

    2003-08-01

    OAK-B135 The quiescent H-mode (QH-mode) is an ELM-free and stationary state mode of operation discovered on DIII-D. This mode achieves H-mode levels of confinement and pedestal pressure while maintaining constant density and radiated power. The elimination of edge localized modes (ELMs) and their large divertor loads while maintaining good confinement and good density control is of interest to next generation tokamaks. This paper reports on the correlations found between selected parameters in a QH-mode database developed from several hundred DIII-D counter injected discharges. Time traces of key plasma parameters from a QH-mode discharge are shown. On DIII-D the negative going plasma current (a) indicates that the beam injection direction is counter to the plasma current direction, a common feature of all QH-modes. The D{sub {alpha}} time behavior (c) shows that soon after high powered beam heating (b) is applied, the discharge makes a transition to ELMing H-mode, then the ELMs disappear, indicating the start of the QH period that lasts for the remainder of the high power beam heating (3.5 s). Previously published work showing density and temperature profiles indicates that long-pulse, high-triangularity QH discharges develop an internal transport barrier in combination with the QH edge barrier. These discharges are known as quiescent, double-barrier discharges (QDB). The H-factor (d) and stored energy (c) rise then saturate at a constant level and the measured axial and minimum safety factors remain above 1.0 for the entire QH duration. During QDB operation the performance of the plasma can be very good, with {beta}{sub N}*H{sub 89L} product reaching 7 for > 10 energy confinement times. These discharges show promise that a stationary state can be achieved.

  6. [Dutch radiodiagnosis from an international viewpoint].

    PubMed

    de Valois, J C

    1990-06-02

    A quantitative description of diagnostic radiology is given in terms of radiological density (the number of radiological examinations per 1000 inhabitants), consumption of roentgen film and contrast media. The data concerning examinations were recorded by a yearly inquiry system addressing all Dutch radiologists. The consumption of film and contrast media were derived from the data banks of the industries. In comparing these data with the data for Western Europe, Japan and the United States it is remarkable that diagnostic radiology scores lowest in regard to density, film consumption and use of contrast media. Only in the use of 35 mm cinefilm (coronary angiography) is The Netherlands number 2 on the list preceded by the United States. As a consequence radiation exposure of the population caused by diagnostic radiology is low in The Netherlands. Although the technical condition of the equipment is good due to regular and preventive service the life-span of the radiological equipment is gradually increasing beyond the limits of the normal economic depreciation. Growing arrears are found in the application of new technology: ultrasound, computer tomography and magnetic resonance imaging. The substitution of high osmolar contrast media by low osmolar media is also lagging behind.

  7. Dutch Open Telescope: status, results, prospects

    NASA Astrophysics Data System (ADS)

    Rutten, Robert J.; Sütterlin, Peter; de Wijn, Alfred G.; Hammerschlag, Robert H.; Bettonvil, Felix C. M.; Hoogendoorn, Piet W.; Jägers, Aswin P. L.

    2002-12-01

    The Dutch Open Telescope (DOT) on La Palma is a revolutionary telescope achieving high-resolution imaging of the solar surface. The DOT combines a pioneering open design at an excellent wind-swept site with image restoration through speckle interferometry. Its open principle is now followed in major solar-telescope projects elsewhere. In the past three years the DOT became the first solar telescope to regularly obtain 0.2" resolution in extended image sequences, i.e., reaching the diffraction limit of its 45-cm primary mirror. Our aim for 2003-2005 is to turn the DOT into a 0.2" tomographic mapper of the solar atmosphere with frequent partnership in international multi-telescope campaigns through student-serviced time allocation. After 2005 we aim to triple the DOT resolution to 0.07" by increasing the aperture to 140 cm and to renew the speckle cameras and the speckle pipeline in order to increase the field size and sequence duration appreciably. These upgrades will maintain the DOT's niche as a tomographic high-resolution mapper in the era when GREGOR, Solar-B and SDO set the stage.

  8. Dutch Open Telescope: Status and Prospects

    NASA Astrophysics Data System (ADS)

    Rutten, R. J.; Hammerschlag, R. H.; Bettonvil, F. M.; Suetterlin, P.

    2000-10-01

    The Dutch Open Telescope (DOT) on La Palma in the Canary Islands is a small but revolutionary solar telescope of which the image quality matches the superb imaging of the Swedish Vacuum Solar Telescope (from whose building the DOT is operated). The DOT is an open parabolic 45cm reflector on an open 15m high tower, relying on mirror flushing by the trade winds that bring the best seeing at La Palma to avoid internal turbulence. A water-cooled field stop in the primary image reflects most sunlight and heat out of the telescope. The first data from the DOT combined with speckle reconstruction have yielded sunspot movies of outstanding quality. At present, a multi-channel imaging system is in construction for simultaneous registration of speckle sequences in the G band, in Ca II K and in Hα. The data pipeline permits continuous speckle data acquisition up to 0.5 Tb per day. The advantage of speckle reconstruction over adaptive optics is the much larger field of the restored scene, with the DOT camera's 100x130 arcsec at 0.2 arcsec resolution. The DOT science program is to study magnetic topology and dynamics throughout the photosphere and chromosphere.

  9. Six-field two-fluid simulations of ELM power depositions on divertor target in real tokamak geometry using BOUT + + code

    NASA Astrophysics Data System (ADS)

    Xia, T. Y.; Xu, X. Q.; Fenstermacher, M. E.

    2013-10-01

    The six-field two-fluid model based on the Braginskii equations in BOUT + + simulation framework is used to study the edge localized modes (ELMs) in realistic tokamak discharges of DIII-D and EAST with the experimentally measured profiles of density, radial electric field, electron and ion temperatures as the initial conditions. The simulations with two different resolutions on the lower single-null geometry are done to describe the evolutions of pedestal energy loss, density profile and heat flux on divertor through the ELM event. The simulation for high resolution shows much faster energy loss than the low resolution one, and leads to the twice of the amplitude for ion heat flux. Our high simulations show that the total energy loss for the small ELM with high frequency is well consistent with the measurement. The amplitudes of heat flux on divertor target are comparable with the early time evolutions of the IR heat flux measurement. Plasma sheath boundary conditions (SBC) are implemented at the divertor plate and they can effectively broaden the heat flux distribution at the outer plate compared to the Dirichlet boundary conditions. The poloidal structures of the heat flux on divertor target will be reported in this paper. This work was done under the US DoE by LLNL Contract DE-AC52-07NA27344 and is supported by the China NSF No 10721505, the NMCFSP Contracts 2011GB107001 and 2011GB105003.

  10. Measurement of Type-I ELM Pulse Propagation in Scrape-Off Layer Using Optical System of Motional Stark Effect Diagnostics in JT-60U

    NASA Astrophysics Data System (ADS)

    Suzuki, Takahiro; Oyama, Naoyuki; Asakura, Nobuyuki

    2009-11-01

    Propagation of plasma ejected by type-I ELM has been measured in scrape-off layer (SOL), using optical system of motional Stark effect (MSE) diagnostics in JT-60U as beam emission spectroscopy (BES) diagnostics. This MSE/BES system measures Dalpha emission from heating neutral beam excited by collisions with the ejected plasma, as well as background light (e.g. bremsstrahlung). In order to separate the beam emission and the background light, a two-wavelength detector is introduced into the MSE/BES system The detector observes simultaneously at the same spatial point in two distinct wavelengths using two photomultiplier tubes through two interference filters. One of the filters is adjusted to the central wavelength of the beam emission and the other is outside the beam emission spectrum Subtracting the background light, temporal change in the net beam emission in SOL has been evaluated Comparing conditionally-averaged beam emission with respect to 594 ELMs at 5 spatial channels (0.02-0.3 m outside the main plasma near equatorial plane), radial velocity of the ELM pulse propagation in SOL is about 0.8-1.8 km/s. Work supported by Grand-in-Aid for Young Scientists (B) No. 20760586

  11. Hybrid-Like Discharges With 2/1 Flux-Pumping Due to ELM-NTM Coupling in DIII-D

    NASA Astrophysics Data System (ADS)

    King, J. D.; Lasnier, C. J.; Lanctot, M. J.; Makowski, M. A.; Holcomb, C. T.; Allen, S. L.; Meyer, W. H.; La Haye, R. J.; Petty, C. C.; Osborne, T. H.; Groebner, R. J.; Luce, T. C.; Volpe, F.; Austin, M. E.; Morse, E. C.

    2011-10-01

    Edge localized mode (ELM)-neoclassical tearing mode (NTM) coupling pumps poloidal flux from the core to the edge in hybrid discharges, contributing to flattening of the safety factor profile and avoidance of sawteeth. Direct motional Stark effect diagnostic analysis of internal magnetic field pitch angles show 2/1 NTMs exhibit stronger magnetic flux-pumping than typical hybrids, albeit at lower beta. This 2/1 flux-pumping is present during partial electron cyclotron current drive NTM suppression. This finding may lead to an alternative discharge with normalized fusion performance exceeding that required for Qfus = 10 operation in ITER. The strength of flux-pumping increases with beta and proximity of the NTM to the ELMing pedestal. Individual ELM-NTM coupling events are successfully modeled using the modified Rutherford equation (MRE). Work supported by US DOE under DE-AC52-07NA27344, DE-FC02-04ER54698, DE-FG03-97ER54415, and DE-FG03-89ER51116.

  12. Melatonin enhances the recovery of cryopreserved shoot tips of American elm (Ulmus Americana L.)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Climate change and the global migrations of people and goods have exposed trees to new diseases and abiotic challenges that threaten the survival of species. In vitro germplasm storage via cryopreservation is an effective tool to ensure conservation of tree species, but plant cells and tissues are e...

  13. Health literacy of Dutch adults: a cross sectional survey

    PubMed Central

    2013-01-01

    Background Relatively little knowledge is available to date about health literacy among the general population in Europe. It is important to gain insights into health literacy competences among the general population, as this might contribute to more effective health promotion and help clarify socio-economic disparities in health. This paper is part of the European Health Literacy Survey (HLS-EU). It aims to add to the body of theoretical knowledge about health literacy by measuring perceived difficulties with health information in various domains of health, looking at a number of competences. The definition and measure of health literacy is still topic of debate and hardly any instruments are available that are applicable for the general population. The objectives were to obtain an initial measure of health literacy in a sample of the general population in the Netherlands and to relate this measure to education, income, perceived social status, age, and sex. Methods The HLS-EU questionnaire was administered face-to-face in a sample of 925 Dutch adults, during July 2011. Perceived difficulties with the health literacy competences for accessing, understanding, appraising and applying information were measured within the domains of healthcare, disease prevention and health promotion. Multiple linear regression analyses were applied to explore the associations between health literacy competences and education, income, perceived social status, age, and sex. Results Perceived difficulties with health information and their association with demographic and socio-economic variables vary according to the competence and health domain addressed. Having a low level of education or a low perceived social status or being male were consistently found to be significantly related to relatively low health literacy scores, mainly for accessing and understanding health information. Conclusions Perceived difficulties with health information vary between competences and domains of

  14. Diagnostic exome sequencing in 266 Dutch patients with visual impairment.

    PubMed

    Haer-Wigman, Lonneke; van Zelst-Stams, Wendy Ag; Pfundt, Rolph; van den Born, L Ingeborgh; Klaver, Caroline Cw; Verheij, Joke Bgm; Hoyng, Carel B; Breuning, Martijn H; Boon, Camiel Jf; Kievit, Anneke J; Verhoeven, Virginie Jm; Pott, Jan Wr; Sallevelt, Suzanne Ceh; van Hagen, Johanna M; Plomp, Astrid S; Kroes, Hester Y; Lelieveld, Stefan H; Hehir-Kwa, Jayne Y; Castelein, Steven; Nelen, Marcel; Scheffer, Hans; Lugtenberg, Dorien; Cremers, Frans Pm; Hoefsloot, Lies; Yntema, Helger G

    2017-02-22

    Inherited eye disorders have a large clinical and genetic heterogeneity, which makes genetic diagnosis cumbersome. An exome-sequencing approach was developed in which data analysis was divided into two steps: the vision gene panel and exome analysis. In the vision gene panel analysis, variants in genes known to cause inherited eye disorders were assessed for pathogenicity. If no causative variants were detected and when the patient consented, the entire exome data was analyzed. A total of 266 Dutch patients with different types of inherited eye disorders, including inherited retinal dystrophies, cataract, developmental eye disorders and optic atrophy, were investigated. In the vision gene panel analysis (likely), causative variants were detected in 49% and in the exome analysis in an additional 2% of the patients. The highest detection rate of (likely) causative variants was in patients with inherited retinal dystrophies, for instance a yield of 63% in patients with retinitis pigmentosa. In patients with developmental eye defects, cataract and optic atrophy, the detection rate was 50, 33 and 17%, respectively. An exome-sequencing approach enables a genetic diagnosis in patients with different types of inherited eye disorders using one test. The exome approach has the same detection rate as targeted panel sequencing tests, but offers a number of advantages. For instance, the vision gene panel can be frequently and easily updated with additional (novel) eye disorder genes. Determination of the genetic diagnosis improved the clinical diagnosis, regarding the assessment of the inheritance pattern as well as future disease perspective.European Journal of Human Genetics advance online publication, 22 February 2017; doi:10.1038/ejhg.2017.9.

  15. Observation of toroidal variation of density gradients and turbulence in DIII-D with 3D fields during ELM suppression

    NASA Astrophysics Data System (ADS)

    Wilcox, R. S.; Schafer, M. W.; Canik, J. M.; Unterberg, E. A.; Wingen, A.; Ferraro, N. M.; McKee, G. R.; Zeng, L.; Rhodes, T. L.

    2016-10-01

    Significant 3D variation in broadband density fluctuations is observed using beam emission spectroscopy and Doppler backscattering near the boundary of weakly 3D plasmas in DIII-D when non-axisymmetric fields are applied to suppress ELMs. The increase in fluctuations is concomitant with an increase in the density gradient measured using profile reflectometry, suggesting that this toroidally localized density gradient could be a mechanism for turbulence destabilization in localized flux tubes. Although changes to magnetic surface topology are shown to be too small to affect turbulence stability directly, two-fluid M3D-C1 simulations find that there is a significant 3D variation of density within flux surfaces in the pedestal. These modeled local density changes modify the local pressure- and density- gradient scale lengths, and measured turbulence is shown to increase on flux tubes with larger gradients. Work supported by the US DOE under contracts DE-AC05-00OR22725, DE-AC02-09CH11466, DE-FG02-08ER54999 and DE-FG02-08ER54984.

  16. Microbiology of wetwood: importance of pectin degradation and Clostridium species in living trees. [Eastern Cottonwood; Block Poplar; American Elm

    SciTech Connect

    Schink, B.; Ward, J.C.; Zeikus, J.G.

    1981-09-01

    Wetwood samples from standing trees of eastern cottonwood (Populus deltoides), black poplar (Populus nigra), and American elm (Ulmus americana) contained high numbers of aerobic and anaerobic pectin-degrading bacteria (10 to the power of 4 to 10 to the power of 6 cells per g of wood). High activity of polygalacturonate lyase (is less than or equal to 0.5 U/ml) was also detected in the fetid liquid that spurted from wetwood zones in the lower trunk when the trees were bored. A prevalent pectin-degrading obligately anaerobic bacterium isolated from these wetwoods was identified as Clostridium butyricum. Pectin decomposition by Clostridium butyricum strain 4P1 was associated with an inducible polygalacturonate lyase and pectin methylesterase, the same types of pectinolytic activity expressed in the wetwood of these trees. The pH optimum of the extracellular polygalacturonate lyase was alkaline (near pH 8.5). In vitro tests with sapwood samples from a conifer (Douglas fir, Pseudotsuga menziesii) showed that tori in membranes of bordered pits are degraded by pure cultures of strain 4P1, polygalacturonate lyase enzyme preparations of strain 4P1, and mixed methanogenic cultures from the tree samples of wetwood. These results provide evidence that pectin in xylem tissue is actively degraded by Clostridium butyricum strain 4P1 via polygalacturonate lyase activity. The importance of pectin degradation by bacteria, including Clostridium species, appears paramount in the formation and maintenance of the wetwood syndrome in certain living trees. (Refs. 38).

  17. Modelling of ELM-averaged power exhaust on JET using the EDGE2D code with variable transport coefficients

    NASA Astrophysics Data System (ADS)

    Kirnev, G.; Fundamenski, W.; Corrigan, G.

    2007-06-01

    The scrape-off layer (SOL) of the JET tokamak has been modelled using a two-dimensional plasma/neutral code, EDGE2D/NIMBUS, with variable transport coefficients, chosen according to nine candidate theories for radial heat transport in the SOL. Comparison of the radial power width on the outer divertor plates, λq, predicted by modelling and measured experimentally in L-mode and ELM-averaged H-mode at JET is presented. Transport coefficients based on classical and neo-classical ion conduction are found to offer the best agreement with experimentally measured λq magnitude and scaling with target power, upstream density and toroidal field. These results reinforce the findings of an earlier study, based on a simplified model of the SOL (Chankin 1997 Plasma Phys. Control. Fusion 39 1059), and support the earlier estimate of the power width at the entrance of the outer divertor volume in ITER, λq ap 4 mm mapped to the outer mid-plane (Fundamenski et al 2004 Nucl. Fusion 44 20).

  18. Comparing vegetation indices for remote chlorophyll measurement of white poplar and Chinese elm leaves with different adaxial and abaxial surfaces

    PubMed Central

    Lu, Shan; Lu, Xingtong; Zhao, Wenli; Liu, Yu; Wang, Zheyi; Omasa, Kenji

    2015-01-01

    Quick non-destructive assessment of leaf chlorophyll content (LCC) is important for studying phenotypes related to plant growth and stress resistance. This study was undertaken to investigate the quantitative relationship between LCC and different vegetation indices (VIs) on both adaxial and abaxial surfaces of white poplar (Populus alba), which has dense tubular hairs on its abaxial surface, and Chinese elm (Ulmus pumila var. pendula), which does not show obvious superficial differences except for lighter colour on the abaxial surface. Some published and newly developed VIs were tested to relate them to LCC. The results showed that most of the published VIs had strong relationships with LCC on the one-surface dataset, but did not show a clear relationship with LCC when both adaxial and abaxial surface reflectance data were included. Among the reflectance indices tested, the modified Datt index, (R 719−R 726)/(R 719−R 743), performed best and is proposed as a new index for remote estimation of chlorophyll content in plants with varying leaf surface structures. It explained 92% of LCC variation in this research, and the root mean square error of the LCC prediction was 5.23 μg/cm2. This new index is insensitive to the effects of adaxial and abaxial leaf surface structures and is strongly related to the variation in reflectance caused by chlorophyll content. PMID:26034132

  19. Characterization of acetylcholinesterase from elm left beetle, Xanthogaleruca luteola and QSAR of temephos derivatives against its activity.

    PubMed

    Sharifi, Mahboobeh; Ghadamyari, Mohammad; Gholivand, Khodayar; Valmoozi, Ali Asghar Ebrahimi; Sajedi, Reza H

    2017-03-01

    Insect acetylcholinesterase (AChE) is the principal target for organophosphate (OP) and carbamate (CB) insecticides. In this research, an AChE from third instar larvae of elm left beetle, Xanthogaleruca luteola was purified by affinity chromatography. The enzyme was purified 75.29-fold with a total yield of 8.51%. As shown on denaturing SDS-PAGE, the molecular mass of purified AChE was 70kDa. The enzyme demonstrated maximum activity at pH7 and 35°C. Furthermore, a series of temephos (Tem) derivatives with the general structure of P(O)XP(O) (1-44) were prepared, synthesized and characterized by (31)P, (13)C, (1)H NMR and FT-IR spectral techniques. The toxicity of 36 new Tem derivatives was screened on the third instar larvae and the compound compound 1,2 cyclohexane-N,N'-bis(N,N'-piperidine phosphoramidate) exhibited the highest insecticidal potential. The method of kinetic analysis is applied in order to obtain the maximum velocity (Vmax), the Michaelis constant (Km) and the parameters characterizing the inhibition type for inhibitors with >75% mortality in preliminary bioassay. The inhibition mechanism was mixed and inhibitory constant (Ki) was calculated as 4.70μM(-1)min(-1) for this compound. Quantitative structure-activity relationship (QSAR) equations of these compounds indicated that the electron orbital energy has major effect on insecticidal properties.

  20. Progress in Performance and Understanding of Steady ELM-free I-modes on Alcator C-Mod

    NASA Astrophysics Data System (ADS)

    Hubbard, A. E.; Whyte, D. G.; Dominguez, A.; Greenwald, M. J.; Howard, N.; Hughes, J. W.; Labombard, B.; Lin, Y.; Lipschultz, B.; Marmar, E. S.; Reinke, M. L.; Rice, J. E.; Terry, J. L.; Walk, J.; White, A. E.; Wukitch, S. J.; Snyder, P.

    2012-10-01

    The I-mode regime of operation has been extended in recent Alcator C-Mod campaigns in duration and robustness, over a wide range of parameters. It features an edge thermal barrier, with L-mode like density profiles and particle transport [1]. I-modes are now routinely maintained in stationary conditions for over 10 τE. They are usually ELM free, a key advantage given the concern over divertor heat pulses on ITER. Instead, a continuous pedestal fluctuation, the ``weakly coherent mode,'' appears to enhance selectively particle over thermal transport. High performance I-modes are usually obtained with unfavorable ion drift direction, and extend to low q95=2.5and νped^*=1.3. τE is in the range of H-mode (H98,y2 up to 1.2), and exhibits less power degradation (W˜P^0.7). Power thresholds for I-mode are higher than typical L-H scalings, and increase with Ip as well as density. The widest power range for I-mode, nearly a factor of two above the L-I threshold, has been obtained in reversed field, lower null discharges at moderate ne. The focus of 2012 experiments is on assessing the density range and dependences, important for extrapolating to ITER, and measuring the pedestal profiles and fluctuations in greater detail.[4pt] [1] Whyte D G et al 2010 Nucl. Fusion 50 105005

  1. Surface modifications on toughened, fine-grained, recrystallized tungsten with repetitive ELM-like pulsed plasma irradiation

    NASA Astrophysics Data System (ADS)

    Kikuchi, Y.; Sakuma, I.; Kitagawa, Y.; Asai, Y.; Onishi, K.; Fukumoto, N.; Nagata, M.; Ueda, Y.; Kurishita, H.

    2015-08-01

    Surface modifications of toughened, fine-grained, recrystallized tungsten (TFGR W) materials with 1.1 wt.% TiC and 3.3 wt.% TaC dispersoids due to repetitive ELM-like pulsed (∼0.15 ms) helium plasma irradiation have been investigated by using a magnetized coaxial plasma gun. No surface cracking at the center part of the TFGR W samples exposed to 20 plasma pulses of ∼0.3 MJ m-2 was observed. The suppression of surface crack formation due to the increase of the grain boundary strength by addition of TiC and TaC dispersoids was confirmed in comparison with a pure W material. On the other hand, surface cracks and small pits appeared at the edge part of the TFGR W sample after the pulsed plasma irradiation. Erosion of the TiC and TaC dispersoids due to the pulsed plasma irradiation could cause the small pits on the surface, resulting in the surface crack formation.

  2. Vapor shielding effects on energy transfer from plasma-gun generated ELM-like transient loads to material surfaces

    NASA Astrophysics Data System (ADS)

    Kikuchi, Y.; Sakuma, I.; Asai, Y.; Onishi, K.; Isono, W.; Nakazono, T.; Nakane, M.; Fukumoto, N.; Nagata, M.

    2016-02-01

    Energy transfer processes from ELM-like pulsed helium (He) plasmas with a pulse duration of ˜0.1 ms to aluminum (Al) and tungsten (W) surfaces were experimentally investigated by the use of a magnetized coaxial plasma gun device. The surface absorbed energy density of the He pulsed plasma on the W surface measured with a calorimeter was ˜0.44 MJ m-2, whereas it was ˜0.15 MJ m-2 on the Al surface. A vapor layer in front of the Al surface exposed to the He pulsed plasma was clearly identified by Al neutral emission line (Al i) measured with a high time resolution spectrometer, and fast imaging with a high-speed visible camera filtered around the Al i emission line. On the other hand, no clear evaporation in front of the W surface exposed to the He pulsed plasma was observed in the present condition. Discussions on the reduction in the surface absorbed energy density on the Al surface are provided by considering the latent heat of vaporization and radiation cooling due to the Al vapor cloud.

  3. Organic compounds in Elm Fork Trinity River water used for public supply near Carrollton, Texas, 2002-05

    USGS Publications Warehouse

    Ging, Patricia B.; Delzer, Gregory C.; Hamilton, Pixie A.

    2009-01-01

    Organic compounds studied in this U.S. Geological Survey (USGS) assessment generally are man-made, including pesticides, solvents, gasoline hydrocarbons, personal-care and domestic-use products, refrigerants, and propellants. A total of 103 of 277 compounds were detected at least once among the 30 samples of source water for a community water system on the Elm Fork Trinity River near Carrollton, Texas, collected approximately monthly during 2002-05. The diversity of compounds detected indicates a variety of different sources and uses (including wastewater discharge, industrial, agricultural, domestic, and others) and different pathways (including overland runoff and groundwater discharge) to drinking-water supplies. Nine compounds were detected year-round in source-water samples, including chloroform, methyl tert-butyl ether (MTBE), and selected herbicide compounds commonly used in the Trinity River Basin and in other urban areas across the United States. About 90 percent of the 42 compounds detected most frequently in source water (in at least 20 percent of the samples) also were detected most frequently in finished water (after treatment but before distribution). Concentrations for all detected compounds in source and finished water generally were less than 0.1 microgram per liter and always less than human-health benchmarks, which are available for about one-half of the detected compounds.

  4. Comparing vegetation indices for remote chlorophyll measurement of white poplar and Chinese elm leaves with different adaxial and abaxial surfaces.

    PubMed

    Lu, Shan; Lu, Xingtong; Zhao, Wenli; Liu, Yu; Wang, Zheyi; Omasa, Kenji

    2015-09-01

    Quick non-destructive assessment of leaf chlorophyll content (LCC) is important for studying phenotypes related to plant growth and stress resistance. This study was undertaken to investigate the quantitative relationship between LCC and different vegetation indices (VIs) on both adaxial and abaxial surfaces of white poplar (Populus alba), which has dense tubular hairs on its abaxial surface, and Chinese elm (Ulmus pumila var. pendula), which does not show obvious superficial differences except for lighter colour on the abaxial surface. Some published and newly developed VIs were tested to relate them to LCC. The results showed that most of the published VIs had strong relationships with LCC on the one-surface dataset, but did not show a clear relationship with LCC when both adaxial and abaxial surface reflectance data were included. Among the reflectance indices tested, the modified Datt index, (R719-R726)/(R719-R743), performed best and is proposed as a new index for remote estimation of chlorophyll content in plants with varying leaf surface structures. It explained 92% of LCC variation in this research, and the root mean square error of the LCC prediction was 5.23 μg/cm(2). This new index is insensitive to the effects of adaxial and abaxial leaf surface structures and is strongly related to the variation in reflectance caused by chlorophyll content.

  5. Preliminary assessment of potential well yields and the potential for artificial recharge of the Elm and Middle James aquifers in the Aberdeen area, South Dakota

    USGS Publications Warehouse

    Emmons, P.J.

    1987-01-01

    A complex hydrologic system exists in the glacial drift overlying the bedrock in the Aberdeen, South Dakota, area. The hydrologic system has been subdivided into three aquifers: the Elm, Middle James, and Deep James. These sand-and-gravel outwash aquifers generally are separated from each other by till or other fine-grained sediments. The Elm aquifer is the uppermost and largest of the aquifers and underlies about 204 sq mi of the study area. The maximum altitude of the top of the Elm aquifer is 1,400 ft and the minimum altitude of the bottom is 1,225 ft. The Middle James aquifer underlies about 172 sq mi of the study area. The maximum altitude of the top of the Middle James aquifer is 1,250 ft and the minimum altitude of the bottom is 1 ,150 ft. The lower-most Deep James aquifer was not evaluated. The quality of the water from the Elm and Middle James aquifer varies considerably throughout the study area. The predominant chemical constituents in the water from the aquifers are sodium and sulfate ions; however, calcium, magnesium, bicarbonate, or chloride may dominate locally. The calculated theoretical total well yield from the Elm and Middle James aquifers ranges from a minimum of 64 cu ft/sec, which may be conservative, to a maximum of 640 cu ft/sec. Based on available data, yields of 100 to 150 cu ft/sec probably can be obtained from properly sited and constructed wells. The feasibility of artificially recharging an aquifer, using the technique of water spreading, depends on the geologic and hydraulic characteristics of the aquifer and of the sediments overlying the aquifer through which the recharge water must percolate. The sites suitable for artificial recharge in the study area were defined as those areas where the average aquifer thickness was > 20 ft and the average thickness of the fine-grained sediments overlying the aquifer was < 10 ft. Using these criteria, about 14 sq mi of the study area are suitable for artificial recharge. Infiltration rates in

  6. Is Dutch Just Another Berber? An Investigation into the Language Preferences of Immigrants in the Netherlands.

    ERIC Educational Resources Information Center

    Weltens, Bert; de Bot, Kees

    1995-01-01

    Reports a study of language learning and language attitudes among immigrants to the Netherlands. Questionnaires obtained from college students studying Dutch showed no evidence that Dutch was threatened by English and indicated that the importance attached to English as an international language did not lessen the value of Dutch for living in the…

  7. Word Order and Finiteness in Dutch and English Broca's and Wernicke's Aphasia

    ERIC Educational Resources Information Center

    Bastiaanse, Roelien; Edwards, Susan

    2004-01-01

    The effect of two linguistic factors in Broca's and Wernicke's aphasia was examined using Dutch and English subjects. Three tasks were used to test (1) the comprehension and (2) the construction of sentences, where verbs (in Dutch) and verb arguments (in Dutch and English) are in canonical versus non-canonical position; (3) the production of…

  8. Dutch Social Democrats and the Struggle for Parental Choice in Education (1890-1940).

    ERIC Educational Resources Information Center

    Karsten, Sjoerd

    2003-01-01

    Asserts the Dutch educational systems' key feature is the principle that parents should be given the opportunity to organize and choose the kind of education they desire. Focuses on the role of the Dutch Social Democrats, the Groningen motion, and the outcome and intellectual foundation of publicly run Dutch schools. (KDR)

  9. Challenging Dutch Holocaust Education: Towards a Curriculum Based on Moral Choices and Empathetic Capacity

    ERIC Educational Resources Information Center

    Boersema, Jacob R.; Schimmel, Noam

    2008-01-01

    We analyse the way in which the Holocaust is taught in The Netherlands, with an emphasis on critically examining the content of secondary school textbooks used to teach Dutch students about the history of the Holocaust. We also interview Dutch educators, government officials and academics about the state of Dutch Holocaust education. Our findings…

  10. [The first Dutch debate on anaesthesia in obstetrics].

    PubMed

    Bijker, Liselotte E

    2015-01-01

    After the publication of the Dutch medical guideline on pharmacological analgesia during childbirth in 2008, the question of whether pharmacological pain relief should be permissible during labour was hotly debated. This discussion has been going on since the second half of the 19th century when the introduction of ether and chloroform was extensively studied and described in Great Britain. This article looks back on the same debate in the Netherlands when inhalational anaesthetics were introduced into obstetrics. Study of historical journals and textbooks, originating in the Netherlands and elsewhere, and of historical medical literature on anaesthesia and obstetrics shows that the Dutch protagonists adopted more nuanced ideas on this issue than many of their foreign colleagues. This description of the first Dutch debate on anaesthesia in obstetrics shows that in fact the issues and arguments are timeless.

  11. End-of-life decisions in dutch neonatology.

    PubMed

    Moratti, Sofia

    2010-01-01

    This contribution describes the regulation of end-of-life decisions in neonatology in the Netherlands. An account is given of the process of formulating rules, which includes a report by the Dutch Association for Paediatrics, two Court rulings, a report by a Consultation Group appointed by the Ministry of Health and a professional Protocol regulating deliberate ending of life in neonatology that was subsequently adopted as the regulation of this type of decision-making at the national level. The paper presents Dutch and comparative data on the attitude of the medical profession towards end-of-life decisions in neonatology and the frequency of such decisions in medical practice.

  12. Internet and Social Media For Health-Related Information and Communication in Health Care: Preferences of the Dutch General Population

    PubMed Central

    Engelen, Lucien JLPG; Berben, Sivera AA; Teerenstra, Steven; Samsom, Melvin; Schoonhoven, Lisette

    2013-01-01

    -related information for the Dutch population. One in 4 persons wants to communicate with their physician via social media channels and it is expected that this number will further increase. Health care providers should explore new ways of communicating online and should facilitate ways for patients to connect with them. Future research should aim at comparing different patient groups and diseases, describing best practices, and determining cost-effectiveness. PMID:24088272

  13. Historical Notes on the Dutch and American-Dutch "schools" in Astronomy and Their Relations with Physics

    NASA Astrophysics Data System (ADS)

    van den Heuvel, Ed

    2006-04-01

    Dutch astronomy and physics experienced two "golden ages". The firstone covered the 17th century, culminating with Christiaan Huygens,inventor of the pendulum clock and the wave theory of light, anddiscoverer of Saturn's rings and largest satellite Titan. The secondone, which lasts till the present, started around 1880 withphysicists Lorentz, van der Waals, Zeeman and Kamerlingh Onnes andastronomer Kapteijn and his pupils De Sitter, van Rhijn, Oort andSchilt. Kapteijn, through his friendship with George Ellery Hale,initiated the strong connection between American and Dutch astronomy,which led to the rise of many Dutch-born astronomers to prominentpositions in the US, from Luyten, Bok, Brouwer, Schilt and Kuiperto Woltjer, Gehrels, and Beckers. The rise of the second "goldenage" appears to be closely related to drastic reforms in the Dutchhigh school and university systems in the last decades of the 19thcentury.

  14. Attitudes toward opioids for refractory dyspnea in COPD among Dutch chest physicians.

    PubMed

    Janssen, Daisy J A; de Hosson, S M; bij de Vaate, Eline; Mooren, Kris J M; Baas, Albert A F

    2015-05-01

    Dyspnea is the most frequently reported symptom of outpatients with advanced chronic obstructive pulmonary disease (COPD). Opioids are an effective treatment for dyspnea. Nevertheless, the prescription of opioids to patients with advanced COPD seems limited. The aims of this study are to explore the attitudes of Dutch chest physicians toward prescription of opioids for refractory dyspnea to outpatients with advanced COPD and to investigate the barriers experienced by chest physicians toward opioid prescription in these patients. All chest physicians (n = 492) and residents in respiratory medicine (n = 158) in the Netherlands were invited by e-mail to complete an online survey. A total of 146 physicians (response rate 22.5%) completed the online survey. Fifty percent of the physicians reported to prescribe opioids for refractory dyspnea in 20% or less of their outpatients with advanced COPD and 18.5% reported never to prescribe opioids in these patients. The most frequently reported barriers toward prescription of opioids were resistance of the patient, fear of possible adverse effects, and fear of respiratory depression. To conclude, Dutch chest physicians and residents in respiratory medicine rarely prescribe opioids for refractory dyspnea to outpatients with advanced COPD. This reluctance is caused by perceived resistance of the patient and fear of adverse effects, including respiratory adverse effects.

  15. Failure and preventive costs of mastitis on Dutch dairy farms.

    PubMed

    van Soest, Felix J S; Santman-Berends, Inge M G A; Lam, Theo J G M; Hogeveen, Henk

    2016-10-01

    Mastitis is an important disease from an economic perspective, but most cost assessments of mastitis include only the direct costs associated with the disease (e.g., production losses, culling, and treatment), which we call failure costs (FC). However, farmers also invest time and money in controlling mastitis, and these preventive costs (PC) also need to be taken into account. To estimate the total costs of mastitis, we estimated both FC and PC. We combined multiple test-day milk records from 108 Dutch dairy farms with information on applied mastitis prevention measures and farmers' registration of clinical mastitis for individual dairy cows. The aim was to estimate the total costs of mastitis and to give insight into variations between farms. We estimated the average total costs of mastitis to be €240/lactating cow per year, in which FC contributed €120/lactating cow per year and PC contributed another €120/lactating cow per year. Milk production losses, discarded milk, and culling were the main contributors to FC, at €32, €20, and €20/lactating cow per year, respectively. Labor costs were the main contributor to PC, next to consumables and investments, at €82, €34, and €4/lactating cow per year, respectively. The variation between farmers was substantial, and some farmers faced both high FC and PC. This variation may have been due to structural differences between farms, different mastitis-causing pathogens, the time at which preventive action is initiated, stockmanship, or missing measures in PC estimates. We estimated the minimum FC to be €34 per lactating cow per yr. All farmers initiated some preventive action to control or reduce mastitis, indicating that farmers will always have mastitis-related costs, because mastitis will never be fully eradicated from a farm. Insights into both the PC and FC of a specific farm will allow veterinary advisors and farmers to assess whether current udder health strategies are appropriate or whether there

  16. How Dutch Employees Experience Freedom of Learning for Work

    ERIC Educational Resources Information Center

    van Dellen, Theo; Heidekamp, Ina

    2015-01-01

    This article focuses on the perceived freedom of Dutch employees to embark on workplace learning in terms of whether they feel it is "voluntary" or "compulsory". The paper is based on the findings of a large international explorative survey carried out by the Workplace Learning (WPL) Research Network (RN2) of the Asia-Europe…

  17. Measurement of Tear Production in English Angora and Dutch Rabbits.

    PubMed

    Rajaei, Seyed Mehdi; Rafiee, Siamak Mashhady; Ghaffari, Masoud Selk; Masouleh, Mohammad N; Jamshidian, Mahmoud

    2016-03-01

    The purpose of this study was to establish normal values for tear production tests in different breeds of domestic rabbits. Healthy adult rabbits (n = 60; 120 eyes) of 2 different breeds (English angora and Dutch; n = 15 of each sex and breed) were used in this study. Tear production was measured by using the 1-min Schirmer tear test (STT), phenol red thread test (PRTT), and endodontic absorbent paper point tear test (EAPTT). In addition, horizontal palpebral fissure length was evaluated as a measure of ocular adnexal dimensions. Tear production (mean ± 1 SD) in English angora rabbits was 5.4 ± 1.6 mm/min according to the STT, 25.0 ± 2.7 mm in 15 s for the PRTT, and 18.8 ± 2.1 mm/min by the EAPTT; in Dutch rabbits, these values were 4.6 ± 1.2 mm/min, 23.6 ± 2.3 mm in 15 s, and 16.9 ± 1.7 mm/min, respectively. Only the EAPTT revealed a significant difference in tear production between English Angora and Dutch rabbits. These results provide reference values for tear production in English Angora and Dutch rabbits according to 3 different quantitative tear film assessment methods.

  18. Smoking among Dutch Elementary Schoolchildren: Gender-Specific Predictors

    ERIC Educational Resources Information Center

    Ausems, M.; Mesters, I.; van Breukelen, G.; De Vries, H.

    2009-01-01

    Higher rates of smoking initiation and continuation by female compared with male adolescents, as found in many developed countries, may call for gender-specific prevention programs. Risk factors of smoking initiation and continuation were examined prospectively (1997-2002) among 3205 Dutch elementary schoolchildren (mean age 11.64) in an…

  19. Developing Classroom Formative Assessment in Dutch Primary Mathematics Education

    ERIC Educational Resources Information Center

    van den Berg, M.; Harskamp, E. G.; Suhre, C. J. M.

    2016-01-01

    In the last two decades Dutch primary school students scored below expectation in international mathematics tests. An explanation for this may be that teachers fail to adequately assess their students' understanding of learning goals and provide timely feedback. To improve the teachers' formative assessment practice, researchers, curriculum…

  20. Two Dutch brothers with Borrone dermato-cardio-skeletal syndrome.

    PubMed

    van Steensel, M A M; Ceulen, R P M; Delhaas, T; de Die-Smulders, C

    2007-06-01

    In 1993, Borrone et al. described two Italian brothers affected by a syndrome of severe acne, mitral valve prolapse, dysmorphic facies, and Scheuermann-like changes of the vertebral column. Since then, no further cases have been reported. Here, we report on two Dutch brothers with many features suggestive of this rare syndrome.

  1. A Collaborative Dialogue--Research in Dutch Language Education

    ERIC Educational Resources Information Center

    Van de Ven, Piet-Hein

    2007-01-01

    In order to address a perceived gap between academic knowledge and education, The Dutch National Advisory Board on Education has suggested that there is a need for more communication between research and practice. For me the gap is more than simply a matter of lack of communication, than a result of the model of Research, Development and Diffusion…

  2. How Dutch employees experience freedom of learning for work

    NASA Astrophysics Data System (ADS)

    van Dellen, Theo; Heidekamp, Ina

    2015-12-01

    This article focuses on the perceived freedom of Dutch employees to embark on workplace learning in terms of whether they feel it is "voluntary" or "compulsory". The paper is based on the findings of a large international explorative survey carried out by the Workplace Learning (WPL) Research Network (RN2) of the Asia-Europe Meeting (ASEM) Lifelong Learning (LLL) Research Hub. The comparative study focused on employees' quest for "freedom of learning for work". This paper reports on the Dutch part of the research, the quantitative results of which seem to indicate that the freedom of learning for work is not as important to Dutch employees as might be expected. In a second phase, to investigate employees' experiences of work-related learning in more depth, the Dutch researchers added a follow-up qualitative study, involving one-on-one interviews. In order to triangulate the results of the quantitative and qualitative research phases, the authors then added a mixed-methods sequential explanatory analysis. They assessed the quality of the collected data in both distinct phases by identifying converging results, which are useful for refining our understanding of learning for work. The paper draws both on rich insights into workplace learning based on this research as well as on theoretical literature which refers to concepts like motivation, subjectivity, work identity and agency in connection with the quest for freedom of learning.

  3. Phonotactics and Morphophonology in Early Child Language: Evidence from Dutch

    ERIC Educational Resources Information Center

    Zamuner, Tania S.; Kerkhoff, Annemarie; Fikkert, Paula

    2012-01-01

    This research investigates children's knowledge of how surface pronunciations of lexical items vary according to their phonological and morphological context. Dutch-learning children aged 2.5 and 3.5 years were tested on voicing neutralization and morphophonological alternations. For instance, voicing does not alternate between the pair…

  4. OpenER, a Dutch Initiative in Open Educational Resources

    ERIC Educational Resources Information Center

    Schuwer, Robert; Mulder, Fred

    2009-01-01

    Over the period 2006-2008, the Dutch Open Universiteit Nederland conducted an experiment in which Open Educational Resources (OER) were offered in an effort to bridge the gap between informal and formal learning and to establish a new style of entry portal to higher education with no barriers at all. OpenER received considerable attention both in…

  5. Development of a Test of Spoken Dutch for Prospective Immigrants

    ERIC Educational Resources Information Center

    De Jong, John H. A. L.; Lennig, Matthew; Kerkhoff, Anne; Poelmans, Petra

    2009-01-01

    Based on a parliamentary vote with broad support, the Ministry of Justice of the Netherlands in December 2003 commissioned the development of an examination system to test the Dutch oral language skills of foreigners who want to immigrate permanently to the Netherlands for economic or family reasons. This assessment would take place in the country…

  6. Citizenship Education and the Dutch National Identity Debate

    ERIC Educational Resources Information Center

    Doppen, Frans H.

    2010-01-01

    As a result of dramatic demographic changes during the last half century as well as a series of recent events surrounding prominent personas, the Dutch have been engaged in an intense debate about their national identity and how citizenship education can contribute to the integration of Muslim immigrants in particular. This article analyses the…

  7. Two Profiles of the Dutch High Performing Employee

    ERIC Educational Resources Information Center

    de Waal, A. A.; Oudshoorn, Michella

    2015-01-01

    Purpose: The purpose of this study is to explore the profile of an ideal employee, to be more precise the behavioral characteristics of the Dutch high-performing employee (HPE). Organizational performance depends for a large part on the commitment of employees. Employees provide their knowledge, skills, experiences and creativity to the…

  8. Collaboration on ICT in Dutch Higher Education: The SURF Approach

    ERIC Educational Resources Information Center

    Boezerooy, Petra; Cordewener, Bas; Liebrand, Wim

    2007-01-01

    In "Thinking Ahead: A Vision of the Role of ICT in Education and Research in the Future, 2007-2010," the higher education institutions in the Netherlands agreed on future strategy. Under the direction of SURF, the Dutch national organization, a collaborative strategy for the application of information and communications technology (ICT)…

  9. Evaluation of Transition in Dutch Senior Secondary Vocational Education.

    ERIC Educational Resources Information Center

    Lazonder, Ard W.; de Jong, Frank P. C. M.

    1999-01-01

    Survey responses from 55 Dutch agricultural vocational schools show that administrators believe that transition, the ability of students to change between training modes or qualification levels easily, has enhanced the flexibility of the qualification system developed under recent national reforms. (SLD)

  10. Dutch Treat for U.S. Database Producers.

    ERIC Educational Resources Information Center

    Boumans, Jak

    1984-01-01

    Reports on investments in the United States (including database activities) by four Dutch publishing companies--Elsevier-NDU, VNU, Kluwer, Wolters Samsom Group. An analysis of the reasons behind these investments, the solidness of the companies, the approach to the U.S. information market, and the knowledge transfer to Europe are highlighted. (EJS)

  11. Alliances in the Dutch BeweegKuur Lifestyle Intervention

    ERIC Educational Resources Information Center

    den Hartog, Franciska; Wagemakers, Annemarie; Vaandrager, Lenneke; van Dijk, Marieke; Koelen, Maria A.

    2014-01-01

    Objective: BeweegKuur (Exercise Therapy) is a Dutch lifestyle programme in which participants are referred by a general practitioner (GP) to a lifestyle advisor. To support participants, regional and local alliances are established. The present study explored the successes and challenges associated with collaboration processes in local BeweegKuur…

  12. Gender Representation and Participation in Dutch Human Geography Departments. Symposium

    ERIC Educational Resources Information Center

    Fortuijn, Joos Droogleever

    2004-01-01

    Since the beginning of the 1970s the under-representation of women in geography has been questioned in several publications. Most articles refer to the situation in English-speaking countries. This paper examines the vertical and horizontal gender segregation in human geography departments in Dutch universities. In spite of several policy measures…

  13. Cognitive and Linguistic Constraints on Phoneme Isolation in Dutch Kindergartners

    ERIC Educational Resources Information Center

    de Graaff, Saskia; Hasselman, Fred; Bosman, Anna M. T.; Verhoeven, Ludo

    2008-01-01

    This study investigated whether task instructions affect sound-isolation performance. The effects of phoneme class and phoneme position were also assessed. Two hundred Dutch kindergartners were presented with a free-sound-isolation task and its constrained counterparts: an initial-, a middle-, and a final-sound-isolation task. All tasks contained…

  14. Attitudes toward Lesbians and Gays among American and Dutch Adolescents

    PubMed Central

    Collier, Kate L.; Horn, Stacey S.; Bos, Henny M. W.; Sandfort, Theo G. M.

    2014-01-01

    Attitudes toward lesbians and gays vary across national populations, and previous research has found relatively more accepting attitudes in the Netherlands as compared to the U.S. In this study, we compared beliefs about and attitudes toward lesbians and gays in samples of Dutch and American heterosexual adolescents, utilizing survey data from 1,080 American adolescents (mean age = 15.86 years) attending two schools and from 1,391 Dutch adolescents (mean age = 16.27 years) attending eight schools. Findings indicated the Dutch participants were more tolerant of lesbians and gays, after adjusting for the gender, age, and racial/ethnic minority status of the participants. However, between-country differences were attenuated by accounting for the beliefs about lesbians and gays that participants used to justify their attitudes. American participants were more likely to justify their attitudes using beliefs related to social norms and religious opposition, while the Dutch participants were more likely to justify their attitudes using beliefs related to individual rights and the biological/genetic basis of homosexuality. The results suggest that the relative importance of particular beliefs about lesbians and gays to attitudes at the group level may be context-dependent but also that certain beliefs are salient to attitudes across national contexts. PMID:24512056

  15. Equality on Different Terms: The Case of Dutch Hindu Schools

    ERIC Educational Resources Information Center

    Merry, Michael S.; Driessen, Geert

    2012-01-01

    In this article the authors examine the reasons for the establishment of Hindu schools in the Netherlands and how the Dutch system of education facilitates these and other voluntarily separate schools. In particular, the authors explore the manner in which Hindu schools aim to cultivate and sustain attachments to their own group through a…

  16. Organisational Factors and Teachers' Professional Development in Dutch Secondary Schools

    ERIC Educational Resources Information Center

    Evers, Arnoud T.; van der Heijden, Beatrice I. J. M.; Kreijns, Karel; Gerrichhauzen, John T. G.

    2011-01-01

    Purpose: The purpose of this paper is to report on a study that investigates the relationship between organisational factors, Teachers' Professional Development (TPD) and occupational expertise. Design/methodology/approach: A survey was administered among 152 Dutch teachers in secondary education. Findings: Analysis of the data revealed that of…

  17. Career Guidance and Student Success in Dutch Higher Vocational Education

    ERIC Educational Resources Information Center

    te Wierik, Mark L. J.; Beishuizen, Jos; van Os, Willem

    2015-01-01

    To enhance student success, a growing number of vocational education and training institutions in the Netherlands are nowadays implementing new career guidance practices in their competence-based approaches to learning. Based on individual-level data of undergraduate first-year full-time students from a Dutch university of applied sciences, this…

  18. Exploring EFL Literature Approaches in Dutch Secondary Education

    ERIC Educational Resources Information Center

    Bloemert, Jasmijn; Jansen, Ellen; van de Grift, Wim

    2016-01-01

    There is an increasing awareness that the inclusion of literature in foreign language (FL) curricula can be beneficial to language learners. Especially, the move towards integrated language and literature curricula is gaining ground. In this study we investigated the way English as a foreign language (EFL) is approached in Dutch secondary…

  19. Sex Differences on the Dutch WAIS-III

    ERIC Educational Resources Information Center

    van der Sluis, Sophie; Posthuma, Danielle; Dolan, Conor V.; de Geus, Eco J. C.; Colom, Roberto; Boomsma, Dorret I.

    2006-01-01

    Using multi-group covariance and means structure analysis (MG-CMSA), this study investigated whether sex differences were present on the Dutch WAIS-III, and if so, whether these sex differences were attributable to differences in general intelligence ("g"). The sample consisted of 294 females and 228 males between 18 and 46 years old.…

  20. Trends in Educational Disadvantage in Dutch Primary School

    ERIC Educational Resources Information Center

    Driessen, Geert; Merry, Michael S.

    2014-01-01

    The central question in this study is whether the language and math delays of the different socio-economic and ethnic minority groups targeted by Dutch educational disadvantage policy have diminished or not. Data are from the years 1995, 1999, 2003 and 2008. Information from a total of 90,000 pupils in Grades 2 and 8 was selected to represent the…

  1. The Prevalence of Poor Reading in Dutch Special Elementary Education

    ERIC Educational Resources Information Center

    van Bon, Wim H. J.; Bouwmans, Mieke; Broeders, Ivy N. L. D. C.

    2006-01-01

    The relative frequency of poor readers in Dutch general elementary education (GEE) and special elementary education (SEE) and the characteristics of their reading performance were investigated using a lexical decision procedure. According to the same norms that identified 9% of students as poor readers in GEE, no less than 73% of the students in…

  2. Stylizing Standard Dutch by Moroccan Boys in Antwerp

    ERIC Educational Resources Information Center

    Jaspers, Jurgen

    2006-01-01

    This article examines ethnographic data that show Belgian adolescents of Moroccan descent stylizing Standard Dutch. Analysis addresses the importance of this variety in Belgian-Flemish society and in the school these boys attended, and shows how in interviews with Moroccan boys the hegemonic status of this variety is generally accepted. In…

  3. Applying Dutch and US Versions of the BSID-II in Dutch Children Born Preterm Leads to Different Outcomes

    ERIC Educational Resources Information Center

    Westera, J. J.; Houtzager, B. A.; Overdiek, B.; van Wassenaer, A. G.

    2008-01-01

    The aim of the present study was to evaluate whether the application of Dutch versus US test procedures and norms of the Bayley Scales of Infant Development-2nd edition (BSID-II) leads to different developmental outcomes. The BSID-II was administered to 376 preterm infants (191 males, 185 females; mean gestational age 30wks [SD 2.7], mean…

  4. An ELM-resilient rf arc detection system for DIII-D based on electromagnetic and sound emissions from the arc

    SciTech Connect

    Phelps, D.A.

    1997-04-01

    Two detection methods based solely on sound and electromagnetic emissions form the arc are presented. Detection of arc induced sound signals 40 to 50 dB above background noise are observed. Detection of arc induced low radio frequency (HF) electromagnetic noise levels 20 to 60 dB above background are observed. The arc noise is randomly strongest on side A and/or B of the DIII-D rf system. The sum of these sensors correlates with tripping due to an increase in the rf reflection coefficient. The sensors are resilient to ELMs and other plasma noise.

  5. An ELM-resilient RF arc detection system for DIII-D based on electromagnetic and sound emissions from the arc

    SciTech Connect

    Phelps, D.A.

    1997-04-01

    Two detection methods based solely on sound and electromagnetic emissions from the arc are presented. Detection of arc induced sound signals 40 to 50 dB above background noise are observed. Detection of arc induced low radio frequency (HF) electromagnetic noise levels 20 to 60 dB above background are observed. The arc noise is randomly strongest on side A and/or B of the DIII-D rf system. The sum of these sensors correlates with tripping due to an increase in the rf reflection coefficient. The sensors are resilient to ELMs and other plasma noise. {copyright} {ital 1997 American Institute of Physics.}

  6. An ELM-resilient RF arc detection system for DIII-D based on electromagnetic and sound emissions from the arc

    NASA Astrophysics Data System (ADS)

    Phelps, D. A.

    1997-04-01

    Two detection methods based solely on sound and electromagnetic emissions from the arc are presented. Detection of arc induced sound signals 40 to 50 dB above background noise are observed. Detection of arc induced low radio frequency (HF) electromagnetic noise levels 20 to 60 dB above background are observed. The arc noise is randomly strongest on side A and/or B of the DIII-D rf system. The sum of these sensors correlates with tripping due to an increase in the rf reflection coefficient. The sensors are resilient to ELMs and other plasma noise.

  7. Impurity confinement and transport in high confinement regimes without edge localized modes on DIII-D [Impurity confinement and transport in high confinement regimes without ELMs on DIII-D

    SciTech Connect

    Grierson, Brian A.; Burrell, Keith H.; Nazikian, Raffi M.; Solomon, Wayne M.; Garofalo, Andrea M.; Belli, Emily A.; Staebler, Gary M.; Fenstermacher, Max E.; McKee, George R.; Evans, Todd E.; Orlov, D. M.; Smith, S. P.; Chrobak, C.; Chrystal, C.

    2015-04-17

    Here, impurity transport in the DIII-D tokamak is investigated in stationary high confinement (H-mode) regimes without edge localized modes (ELMs). In plasmas maintained by resonant magnetic perturbation (RMP) ELM-suppression and QH-mode the confinement time of fluorine (Z=9) is equivalent to that in ELMing discharges with 40 Hz ELMs. For selected discharges with impurity injection the impurity particle confinement time compared to the energy confinement time is in the range of τpe ≈ 2 $-$ 3. In QH-mode operation the impurity confinement time is shown to be smaller for intense, coherent magnetic and density fluctuations of the edge harmonic oscillation than weaker fluctuations. Transport coefficients are derived from the time evolution of the impurity density profile and compared to neoclassical and turbulent transport models NEO and TGLF. Neoclassical transport of fluorine is found to be small compared to the experimental values. In the ELMing and RMP ELM-suppressed plasma the impurity transport is affected by the presence of tearing modes. For radii larger than the mode radius the TGLF diffusion coefficient is smaller than the experimental value by a factor of 2-3, while the convective velocity is within error estimates. Low levels of diffusion are observed for radii smaller than the tearing mode radius. In the QH-mode plasma investigated, the TGLF diffusion coefficient higher inside of ρ = 0.4 and lower outside of 0.4 than the experiment, and the TGLF convective velocity is more negative by a factor of approximately 1.7.

  8. Impurity confinement and transport in high confinement regimes without edge localized modes on DIII-D [Impurity confinement and transport in high confinement regimes without ELMs on DIII-D

    DOE PAGES

    Grierson, Brian A.; Burrell, Keith H.; Nazikian, Raffi M.; ...

    2015-04-17

    Here, impurity transport in the DIII-D tokamak is investigated in stationary high confinement (H-mode) regimes without edge localized modes (ELMs). In plasmas maintained by resonant magnetic perturbation (RMP) ELM-suppression and QH-mode the confinement time of fluorine (Z=9) is equivalent to that in ELMing discharges with 40 Hz ELMs. For selected discharges with impurity injection the impurity particle confinement time compared to the energy confinement time is in the range of τp/τe ≈ 2 $-$ 3. In QH-mode operation the impurity confinement time is shown to be smaller for intense, coherent magnetic and density fluctuations of the edge harmonic oscillation thanmore » weaker fluctuations. Transport coefficients are derived from the time evolution of the impurity density profile and compared to neoclassical and turbulent transport models NEO and TGLF. Neoclassical transport of fluorine is found to be small compared to the experimental values. In the ELMing and RMP ELM-suppressed plasma the impurity transport is affected by the presence of tearing modes. For radii larger than the mode radius the TGLF diffusion coefficient is smaller than the experimental value by a factor of 2-3, while the convective velocity is within error estimates. Low levels of diffusion are observed for radii smaller than the tearing mode radius. In the QH-mode plasma investigated, the TGLF diffusion coefficient higher inside of ρ = 0.4 and lower outside of 0.4 than the experiment, and the TGLF convective velocity is more negative by a factor of approximately 1.7.« less

  9. Testing a Dutch web-based tailored lifestyle programme among adults: a study protocol

    PubMed Central

    2011-01-01

    Background Smoking, high alcohol consumption, unhealthy eating habits and physical inactivity often lead to (chronic) diseases, such as cardiovascular diseases and cancer. Tailored online interventions have been proven to be effective in changing health behaviours. The aim of this study is to test and compare the effectiveness of two different tailoring strategies for changing lifestyle compared to a control group using a multiple health behaviour web-based approach. Methods In our Internet-based tailored programme, the five lifestyle behaviours of smoking, alcohol intake, fruit consumption, vegetable consumption, and physical activity are addressed. This randomized controlled trial, conducted among Dutch adults, includes two experimental groups (i.e., a sequential behaviour tailoring condition and a simultaneous behaviour tailoring condition) and a control group. People in the sequential behaviour tailoring condition obtain feedback on whether their lifestyle behaviours meet the Dutch recommendations. Using a step-by-step approach, they are stimulated to continue with a computer tailored module to change only one unhealthy behaviour first. In the course of the study, they can proceed to change a second behaviour. People in the simultaneous behaviour tailoring condition receive computer tailored feedback about all their unhealthy behaviours during their first visit as a stimulation to change all unhealthy behaviours. The experimental groups can re-visit the website and can then receive ipsative feedback (i.e., current scores are compared to previous scores in order to give feedback about potential changes). The (difference in) effectiveness of the different versions of the programme will be tested and compared to a control group, in which respondents only receive a short health risk appraisal. Programme evaluations will assess satisfaction with and appreciation and personal relevance of the intervention among the respondents. Finally, potential subgroup differences

  10. Increase in number of helminth species from Dutch red foxes over a 35-year period

    PubMed Central

    2014-01-01

    Background The red fox (Vulpes vulpes) is host to a community of zoonotic and other helminth species. Tracking their community structure and dynamics over decades is one way to monitor the long term risk of parasitic infectious diseases relevant to public and veterinary health. Methods We identified 17 helminth species from 136 foxes by mucosal scraping, centrifugal sedimentation/flotation and the washing and sieving technique. We applied rarefaction analysis to our samples and compared the resulting curve to the helminth community reported in literature 35 years ago. Results Fox helminth species significantly increased in number in the last 35 years (p-value <0.025). Toxascaris leonina, Mesocestoides litteratus, Trichuris vulpis and Angiostrongylus vasorum are four new veterinary-relevant species. The zoonotic fox tapeworm (E. multilocularis) was found outside the previously described endemic regions in the Netherlands. Conclusions Helminth fauna in Dutch red foxes increased in biodiversity over the last three decades. PMID:24708710

  11. Siebrandus Sixtius: evidence of rheumatoid arthritis of the robust reaction type in a seventeenth century Dutch priest.

    PubMed Central

    Dequeker, J

    1992-01-01

    Rheumatoid arthritis of the robust reaction type has been diagnosed in a seventeenth century Dutch priest, Siebrandus Sixtius, based on pictorial evidence of typical hand deformities and historical evidence affirming that he had chronic nodular rheumatism for many years. This case report, in conjunction with other pictorial depictions of probable rheumatoid arthritis, questions the view that rheumatoid arthritis is a modern disease which prevailed in the New World and was found in the Old World only after the discovery of America. Images PMID:1586264

  12. Sex pheromone chemistry and field trapping studies of the elm spanworm Ennomos subsignaria (Hübner) (Lepidoptera:Geometridae).

    PubMed

    Ryall, Krista; Silk, Peter J; Wu, Junping; Mayo, Peter; Lemay, Matthew A; MaGee, David

    2010-08-01

    The elm spanworm, Ennomos subsignaria (Hübner), occurs throughout Canada and the eastern United States and can be a destructive forest pest on a wide range of deciduous trees. Gas chromatography/mass spectrometry (GC/MS) and coupled gas chromatographic-electroantennographic detection (GC/EAD) analysis of pheromone gland extracts, in combination with chemical synthesis and field trapping studies have identified (2S, 3R)-2-((Z)-oct-2'-enyl)-3-nonyl oxirane (hereafter Z6-9S, 10R-epoxy-19:H) as the female-produced sex pheromone. Significantly more male moths were captured between 1-100 microg loadings of this compound on red rubber septa in sticky traps compared to blank (unbaited) traps; catches then declined at higher dosages (500-1000 microg). The other isomeric enantiomer, (2R, 3S)-2-[(Z)-oct-2'-enyl]-3-nonyl oxirane (Z6-9R, 10S-epoxy-19:H), at a 10-microg dosage did not elicit trap capture. The likely precursor to the active epoxide, (Z, Z)-6, 9-nonadecadiene ((Z, Z)-6, 9-19:H), identified in virgin female sex pheromone glands, did not elicit trap capture either, and inhibited trap capture when combined with the active epoxide. Racemic 2-((Z)-oct-2'-enyl)-3-nonyl oxirane showed no significant difference in trap capture compared with Z6-9S, 10R-epoxy-19:H, indicating that the opposite enantiomer was not antagonistic. The addition of the EAD-active diene epoxide enantiomers (2S, 3R)-2-[(Z, Z)-octa-2', 5'-dienyl]-3-nonyl oxirane or (2R, 3S)-2-[(Z, Z)-octa-2', 5'-dienyl]-3-nonyl oxirane in admixture with Z6-9S, 10R-epoxy-19:H (at 10% of the latter) did not enhance or decrease trap capture compared to Z6-9S, 10R-epoxy-19:H oxirane alone, so they are not likely pheromone components. This pheromone, impregnated in rubber septa at less than 100-microg dosage, can now be used as a trap bait to develop detection and monitoring strategies for this insect.

  13. Sex pheromone chemistry and field trapping studies of the elm spanworm Ennomos subsignaria (Hübner) (Lepidoptera:Geometridae)

    NASA Astrophysics Data System (ADS)

    Ryall, Krista; Silk, Peter J.; Wu, Junping; Mayo, Peter; Lemay, Matthew A.; Magee, David

    2010-08-01

    The elm spanworm, Ennomos subsignaria (Hübner), occurs throughout Canada and the eastern United States and can be a destructive forest pest on a wide range of deciduous trees. Gas chromatography/mass spectrometry (GC/MS) and coupled gas chromatographic-electroantennographic detection (GC/EAD) analysis of pheromone gland extracts, in combination with chemical synthesis and field trapping studies have identified (2 S, 3 R)-2-(( Z)-oct-2'-enyl)-3-nonyl oxirane (hereafter Z6-9 S, 10 R-epoxy-19:H) as the female-produced sex pheromone. Significantly more male moths were captured between 1-100 μg loadings of this compound on red rubber septa in sticky traps compared to blank (unbaited) traps; catches then declined at higher dosages (500-1000 μg). The other isomeric enantiomer, (2 R, 3 S)-2-[( Z)-oct-2'-enyl]-3-nonyl oxirane ( Z6-9 R, 10 S-epoxy-19:H), at a 10-μg dosage did not elicit trap capture. The likely precursor to the active epoxide, ( Z, Z)-6, 9-nonadecadiene (( Z, Z)-6, 9-19:H), identified in virgin female sex pheromone glands, did not elicit trap capture either, and inhibited trap capture when combined with the active epoxide. Racemic 2-((Z)-oct-2'-enyl)-3-nonyl oxirane showed no significant difference in trap capture compared with Z6-9 S, 10 R-epoxy-19:H, indicating that the opposite enantiomer was not antagonistic. The addition of the EAD-active diene epoxide enantiomers (2 S, 3 R)-2-[( Z, Z)-octa-2', 5'-dienyl]-3-nonyl oxirane or (2 R, 3 S)-2-[( Z, Z)-octa-2', 5'-dienyl]-3-nonyl oxirane in admixture with Z6-9 S, 10 R-epoxy-19:H (at 10% of the latter) did not enhance or decrease trap capture compared to Z6-9 S, 10 R-epoxy-19:H oxirane alone, so they are not likely pheromone components. This pheromone, impregnated in rubber septa at less than 100-μg dosage, can now be used as a trap bait to develop detection and monitoring strategies for this insect.

  14. Vibrio vulnificus outbreaks in Dutch eel farms since 1996: strain diversity and impact.

    PubMed

    Haenen, O L M; van Zanten, E; Jansen, R; Roozenburg, I; Engelsma, M Y; Dijkstra, A; Boers, S A; Voorbergen-Laarman, M; Möller, A V M

    2014-04-03

    Vibrio vulnificus is a potentially zoonotic bacterial pathogen of fish, which can infect humans (causing necrotic fasciitis). We analysed 24 V. vulnificus isolates (from 23 severe eel disease outbreaks in 8 Dutch eel farms during 1996 to 2009, and 1 clinical strain from an eel farmer) for genetic correlation and zoonotic potential. Strains were typed using biotyping and molecular typing by high-throughput multilocus sequence typing (hiMLST) and REP-PCR (Diversilab®). We identified 19 strains of biotype 1 and 5 of biotype 2 (4 from eels, 1 from the eel farmer), that were subdivided into 8 MLST types (ST) according to the international standard method. This is the first report of V. vulnificus biotype 1 outbreaks in Dutch eel farms. Seven of the 8 STs, of unknown zoonotic potential, were newly identified and were deposited in the MLST database. The REP-PCR and the MLST were highly concordant, indicating that the REP-PCR is a useful alternative for MLST. The strains isolated from the farmer and his eels were ST 112, a known potential zoonotic strain. Antimicrobial resistance to cefoxitin was found in most of the V. vulnificus strains, and an increasing resistance to quinolones, trimethoprim + sulphonamide and tetracycline was found over time in strain ST 140. Virulence testing of isolates from diseased eels is recommended, and medical practitioners should be informed about the potential risk of zoonotic infections by V. vulnificus from eels for the prevention of infection especially among high-risk individuals. Additional use of molecular typing methods such as hiMLST and Diversilab® is recommended for epidemiological purposes during V. vulnificus outbreaks.

  15. Ketoolivosyl-tetracenomycin C: a new ketosugar bearing tetracenomycin reveals new insight into the substrate flexibility of glycosyltransferase ElmGT

    PubMed Central

    Nybo, S. Eric; Shabaan, Khaled A.; Kharel, Madan K.; Salas, José A.; Méndez, Carmen; Sutardjo, Happy; Rohr, Jürgen

    2012-01-01

    A new tetracenomycin analogue, 8-demethyl-8-(4′-keto)-α-l-olivosyl-tetracenomycin C, was generated through combinatorial biosynthesis. Streptomyces lividans TK 24 (cos16F4) was used as a host for expression of a “sugar plasmid” (pKOL) directing the biosynthesis of NDP-4-keto-l-olivose. This strain harbors all of the genes necessary for production of 8-demethylt-etracenomycin C and the sugar flexible glycosyltransferase ElmGT. To the best of our knowledge, this report represents the first characterization of a tetracenomycin derivative decorated with a ketosugar moiety. Also, as far as we know, 4-keto-l-olivose has only been described as an intermediate of oleandomycin biosynthesis, but has not been described before as an appendage for a polyketide compound. Furthermore, this report gives further insight into the substrate flexibility of ElmGT to include an NDP-ketosugar, which is unusual and is rarely observed among glycosyltransferases from antibiotic biosynthetic pathways. PMID:22361136

  16. Elm leaves 'warned' by insect egg deposition reduce survival of hatching larvae by a shift in their quantitative leaf metabolite pattern.

    PubMed

    Austel, Nadine; Eilers, Elisabeth J; Meiners, Torsten; Hilker, Monika

    2016-02-01

    Plants may take insect eggs on their leaves as a warning of future herbivory and intensify their defence against feeding larvae. Responsible agents are, however, largely unknown, and little knowledge is available on this phenomenon in perennial plants. We investigated how egg deposition affects the anti-herbivore defence of elm against the multivoltine elm leaf beetle. Prior egg deposition caused changes in the quality of feeding-damaged leaves that resulted in increased larval mortality and reduced reproductive capacity of the herbivore by harming especially female larvae. Chemical analyses of primary and secondary leaf metabolites in feeding-damaged, egg-free (F) and feeding-damaged, egg-deposited (EF)-leaves revealed only small differences in concentrations when comparing metabolites singly. However, a pattern-focused analysis showed clearly separable patterns of (F) and (EF)-leaves because of concentration differences in especially nitrogen and phenolics, of which robinin was consumed in greater amounts by larvae on (EF) than on (F)-leaves. Our study shows that insect egg deposition mediates a shift in the quantitative nutritional pattern of feeding-damaged leaves, and thus might limit the herbivore's population growth by reducing the number of especially female herbivores. This may be a strategy that pays off in a long run particularly in perennial plants against multivoltine herbivores.

  17. Combatting Electoral Traces: The Dutch Tempest Discussion and Beyond

    NASA Astrophysics Data System (ADS)

    Pieters, Wolter

    In the Dutch e-voting debate, the crucial issue leading to the abandonment of all electronic voting machines was compromising radiation, or tempest: it would be possible to eavesdrop on the choice of the voter by capturing the radiation from the machine. Other countries, however, do not seem to be bothered by this risk. In this paper, we use actor-network theory to analyse the socio-technical origins of the Dutch tempest issue in e-voting, and we introduce concepts for discussing its implications for e-voting beyond the Netherlands. We introduce the term electoral traces to denote any physical, digital or social evidence of a voter’s choices in an election. From this perspective, we provide a framework for risk classification as well as an overview of countermeasures against such traces.

  18. Epilepsy and self-identity among the Dutch.

    PubMed

    Reis, R

    2001-01-01

    This article discusses the relationship between societal images of epilepsy and the self-identity of Dutch people with epilepsy. I show that the condition of having epilepsy is only constructed as chronic if people continue to have seizures. Chronic epilepsy, or "real epilepsy" as it is sometimes called, is not burdened with such classic stereotypes as "the epileptic personality" or "the epileptic genius." However, Dutch people replace these stereotypes with stereotypes based on ideas about "tension" and "weak spots"--phenomena that are allegedly linked to "sensitive," "brooding" types of people and that are thought to trigger epileptic seizures. Thus there develops a notion of self related to frequency of epileptic seizures. Those who are close to people with epilepsy--relatives and non-medical professionals--play an important role in this development.

  19. Level II scour analysis for Bridge 42 (HARDELMSTR0042) on Elm Street, crossing Cooper Brook, Hardwick, Vermont

    USGS Publications Warehouse

    Olson, Scott A.

    1996-01-01

    This report provides the results of a detailed Level II analysis of scour potential at structure HARDELMSTR0042 on Elm Street crossing Cooper Brook, Hardwick, Vermont (figures 1–8). A Level II study is a basic engineering analysis of the site, including a quantitative analysis of stream stability and scour (U.S. Department of Transportation, 1993). Results of a Level I scour investigation also are included in Appendix E of this report. A Level I investigation provides a qualitative geomorphic characterization of the study site. Information on the bridge, gleaned from Vermont Agency of Transportation (VTAOT) files, was compiled prior to conducting Level I and Level II analyses and is found in Appendix D. The site is in the New England Upland section of the New England physiographic province in north-central Vermont. The 16.6-mi2 drainage area is in a predominantly rural and forested basin. In the vicinity of the study site, the overbanks are primarily grass covered with some brush along the immediate channel banks except the upstream right bank and overbank which is forested and the downstream left overbank which has a lumberyard. In the study area, Cooper Brook has a sinuous channel with a slope of approximately 0.005 ft/ft, an average channel top width of 50 ft and an average channel depth of 6 ft. The predominant channel bed materials are sand and gravel with a median grain size (D50) of 1.25 mm (0.00409 ft). The geomorphic assessment at the time of the Level I and Level II site visit on July 24, 1995, indicated that the reach was stable. The Elm Street crossing of Cooper Brook is a 39-ft-long, two-lane bridge consisting of one 37-foot concrete span (Vermont Agency of Transportation, written communication, March 17, 1995). The bridge is supported by vertical, concrete abutments with wingwalls. The channel is skewed approximately 40 degrees to the opening while the opening-skew-to-roadway is 45 degrees. On August 17, 1995 the site was revisited to investigate

  20. Processing grammatical gender in Dutch: Evidence from eye movements.

    PubMed

    Brouwer, Susanne; Sprenger, Simone; Unsworth, Sharon

    2017-03-03

    Previous research has demonstrated that grammatical gender in Dutch is typically acquired late. Most of this work used production data only, and consequently children's knowledge of Dutch gender may have been underestimated. In this study, therefore, we examined whether 49 4- to 7-year-old Dutch-speaking children (and 19 adult controls) were able to use gender marking in the article preceding the object label during online sentence processing to (a) anticipate the upcoming object label or to (b) facilitate the processing of that label as it is presented. In addition, we investigated whether children's online processing and production of gender marking on articles were related. In an eye-tracking task, participants were presented with sentences and visual displays with two objects, representing nouns of either the same gender (uninformative) or different genders (informative). Children were divided into a non-targetlike group and a targetlike group on the basis of their scores for neuter nouns in the production task. Our analyses examined whether participants could use gender marking anticipatorily (i.e., before the onset of the noun) and facilitatively (i.e., from noun onset). Results showed that Dutch-speaking adults and children who were successful in production used gender marking anticipatorily. However, children who did not systematically produce gender-marked articles used gender marking only facilitatively. These findings reveal that successful online comprehension may in part be possible before targetlike production is completely in place, but at the same time targetlike production may be a trigger for online comprehension to be completely successful.

  1. Autosomal dominant congenital Horner's syndrome in a Dutch family.

    PubMed Central

    Hageman, G; Ippel, P F; te Nijenhuis, F C

    1992-01-01

    A Dutch family is reported with congenital Horner's syndrome in five cases spanning five generations, with symptoms of varying degree but mainly ptosis and meiosis. Heterochromia iridium, anhidrosis, and enophthalmos were not present. The site of the lesion may be in the region between Gasser's ganglion and the short vertical segment of the internal carotid artery near the siphon. There are only four previous reports showing autosomal dominant inheritance of congenital Horner's syndrome. Images PMID:1548493

  2. Autosomal dominant congenital Horner's syndrome in a Dutch family.

    PubMed

    Hageman, G; Ippel, P F; te Nijenhuis, F C

    1992-01-01

    A Dutch family is reported with congenital Horner's syndrome in five cases spanning five generations, with symptoms of varying degree but mainly ptosis and meiosis. Heterochromia iridium, anhidrosis, and enophthalmos were not present. The site of the lesion may be in the region between Gasser's ganglion and the short vertical segment of the internal carotid artery near the siphon. There are only four previous reports showing autosomal dominant inheritance of congenital Horner's syndrome.

  3. Predictors of photo naming: Dutch norms for 327 photos.

    PubMed

    Shao, Zeshu; Stiegert, Julia

    2016-06-01

    In the present study, we report naming latencies and norms for 327 photos of objects in Dutch. We provide norms for eight psycholinguistic variables: age of acquisition, familiarity, imageability, image agreement, objective and subjective visual complexity, word frequency, word length in syllables and letters, and name agreement. Furthermore, multiple regression analyses revealed that the significant predictors of photo-naming latencies were name agreement, word frequency, imageability, and image agreement. The naming latencies, norms, and stimuli are provided as supplemental materials.

  4. Probabilistic environmental risk assessment of zinc in Dutch surface waters.

    PubMed

    Van Sprang, Patrick A; Verdonck, Frederik A M; Vanrolleghem, Peter A; Vangheluwe, Marnix L; Janssen, Colin R

    2004-12-01

    In the framework of the European Union (EU) New and Existing Chemicals Policy, a regional risk assessment for Zn according to the current technical guidance documents and a probabilistic approach, by mathematically integrating both best-fitting exposure concentrations and species-sensitivity distributions into a probabilistic risk quotient distribution using Monte Carlo analysis, was explored for The Netherlands. Zinc is an essential element, and the current probability distributions may not adequately deal with this property. The threshold Pareto distribution provided the best fit to the chronic Zn toxicity data, resulting in a predicted-no-effect concentration (PNECadd) for dissolved Zn of 34.2 microg/L, whereas use of the conventional normal distribution resulted in a PNECadd for dissolved Zn of 14.6 microg/L. The extracted exposure data resulted in a regional predicted environmental concentration (PEC) for dissolved Zn in the Dutch surface waters of 20.1 microg/L and in PECadd values for dissolved Zn of between 15.5 and 17.3 microg/L, depending on the background correction used. The conventional deterministic risk characterization identified a regional risk for Zn in the Dutch surface waters. The more comprehensive probabilistic approach used in the present study, however, identified only very limited potential risks for the Dutch region. A probabilistic median risk, that the environmental concentration is greater than the no-observed-effect concentration of a species in Dutch surface waters (0.5-0.6%), depending on the inclusion of background correction, was obtained from the best-fitting distributions. Because probabilistic approaches provide a quantifiable and improved assessment of risk and quantification of the uncertainty associated with that assessment, these techniques may be considered as a way to improve the EU risk assessment procedures for data-rich substances.

  5. The Stanford Hypnotic Susceptibility Scale, Form C: normative data of a Dutch student sample.

    PubMed

    Näring, G W; Roelofs, K; Hoogduin, K A

    2001-04-01

    Norms for the Dutch language version of the Standford Hypnotic Susceptibility Scale, Form C (SHSS:C; Weitzenhoffer & Hilgard, 1962) are presented. These norms are based upon a sample of 135 students at a Dutch university. Generally, the psychometric properties of the Dutch version of the SHSS:C are similar to other language versions. However, the mean score was somewhat lower than that found in the original norming studies at Stanford University.

  6. Sexual orientation of parents and Dutch family law.

    PubMed

    van Nijnatten, C H

    1995-01-01

    A few years ago, the Dutch government asked for advice about the legal consequences of various living arrangements. One of the main issues concerned the legal consequences thereof for children. In a letter to parliament, the Dutch cabinet confirmed that couples of the same sex would be excluded from being awarded children for adoption. Legal and psychological reasons play an important role in the reasoning of the Dutch government. The harmonious development of children is supposed to be at risk when the child is reared by two adults of the same sex. This article sets out psychological theories and the results of recent research which contradict the argumentation presented in a number of recent reports published by the government. The outcome of most research is that gay and lesbian parents 'perform' as well as heterosexual parents. Excluding lesbian and gay parents from taking responsibility for children seems to be a poor policy which does not take into account the social capacities of the population.

  7. Young Dutch people's experiences of trading sex: a qualitative study.

    PubMed

    van de Walle, Robert; Picavet, Charles; van Berlo, Willy; Verhoeff, Arnoud

    2012-01-01

    In recent years, the subject of transactional sex among young Dutch people has generated a heated social debate in the Netherlands. However, accurate data on this phenomenon are scarce. This article describes the findings of a qualitative study on young Dutch people's experiences of having sex in return for money or a material reward. Thirty in-depth interviews were conducted with young Dutch men and women aged 14 to 24. Participants came from diverse backgrounds in terms of gender, ethnicity, sexual orientation, and socioeconomic status. Experiences of trading sex differed in terms of the motivation to trade sex, the presence or absence of coercion, and the availability of other options for earning money. Participants' feelings about their experiences varied. For most participants, the sex itself was unpleasant and required considerable emotion management. Still, some felt adequately compensated by the reward or felt trading sex was preferable to other jobs. Gender played an important role, with feelings of disgust or shame reported especially by female participants, whereas male participants reported more positive experiences. Interactions involving coercion or financial dependence on trading sex generally had a negative emotional impact. Participants stressed the differences between their own experiences and professional prostitution.

  8. Relative Age Effects in Dutch Adolescents: Concurrent and Prospective Analyses

    PubMed Central

    Jeronimus, Bertus F.; Stavrakakis, Nikolaos; Veenstra, René; Oldehinkel, Albertine J.

    2015-01-01

    The literature on relative age position effects is rather inconsistent. In this study we examined intra-classroom age position (or relative age) effects on Dutch adolescents’ school progress and performance (as rated by teachers), physical development, temperamental development (fear and frustration), and depressive symptoms, all adjusted for age at the time of measurement. Data were derived from three waves of Tracking Adolescents' Individuals Lives Survey (TRAILS) of 2230 Dutch adolescents (baseline mean age 11.1, SD = 0.6, 51% girls). Albeit relative age predicted school progress (grade retention ORs = 0.83 for each month, skipped grade OR = 1.47, both p<.001), our key observation is the absence of substantial developmental differences as a result of relative age position in Dutch adolescents with a normative school trajectory, in contrast to most literature. For adolescents who had repeated a grade inverse relative age effects were observed, in terms of physical development and school performance, as well as on depressive symptoms, favoring the relatively young. Cross-cultural differences in relative age effect may be partly explained by the decision threshold for grade retention. PMID:26076384

  9. Lexical frequency and voice assimilation in complex words in Dutch

    NASA Astrophysics Data System (ADS)

    Ernestus, Mirjam; Lahey, Mybeth; Verhees, Femke; Baayen, Harald

    2004-05-01

    Words with higher token frequencies tend to have more reduced acoustic realizations than lower frequency words (e.g., Hay, 2000; Bybee, 2001; Jurafsky et al., 2001). This study documents frequency effects for regressive voice assimilation (obstruents are voiced before voiced plosives) in Dutch morphologically complex words in the subcorpus of read-aloud novels in the corpus of spoken Dutch (Oostdijk et al., 2002). As expected, the initial obstruent of the cluster tends to be absent more often as lexical frequency increases. More importantly, as frequency increases, the duration of vocal-fold vibration in the cluster decreases, and the duration of the bursts in the cluster increases, after partialing out cluster duration. This suggests that there is less voicing for higher-frequency words. In fact, phonetic transcriptions show regressive voice assimilation for only half of the words and progressive voice assimilation for one third. Interestingly, the progressive voice assimilation observed for higher-frequency complex words renders these complex words more similar to monomorphemic words: Dutch monomorphemic words typically contain voiceless obstruent clusters (Zonneveld, 1983). Such high-frequency complex words may therefore be less easily parsed into their constituent morphemes (cf. Hay, 2000), favoring whole word lexical access (Bertram et al., 2000).

  10. [Dutch-Romanian cooperation in the area of family practice].

    PubMed

    van Es, J C

    2001-10-27

    During the years 1992-2000, there was a cooperative programme between the Romanian general practitioners' association (Societatea Nationala de Medicina Generala) in Romania and the Dutch Foundation for the Advancement of Quality in Healthcare in Romania. A succession of programmes were developed and carried out, which were financed by the Dutch government. The purpose of the cooperative programme was to support the development of Romanian general practice in terms of quality and structure. In the first programme, financed by the Dutch Ministry of Health, Welfare and Sport, about 200 Romanian general practitioners received continuing education. This was followed by a social transformation programme (MATRA) that had two parts: (a) the general practitioners association was supported and advised with respect to improving its organisational efficiency and (b) about 50 carefully selected Romanian general practitioners were trained, in post-academic research, management or teaching. The Romanian authorities accredited these trainees as teachers. The co-operation is being continued in 2001 with the setting up of a sentinel station programme in which 100 Romanian general practitioners collect relevant, representative data on health, illness and practice.

  11. [Topics in clinical dentistry. Trends in the Dutch dental literature].

    PubMed

    van der Sanden, W J; Mettes, T G; Grol, R; Plasschaert, A J; Verdonschot, E H

    1999-10-01

    Aim of the study was to evaluate a method for selecting topics suitable for developing dental clinical practice guidelines in the Netherlands, based on an analysis of Dutch dental journals. A search for dental clinical topics was conducted by analysing Dutch dental journals, magazines and series over the period 1992-1997. The numbers of publications per topic were plotted against the publication years. The number of publications as well as the value of the slope of the linear regression were considered to be indicators of the importance of a topic. 'Dental implants (indication)' had the highest number of publications, followed by 'orthodontic treatment planning' and 'periodontology (indication)'. The topic 'practice hygiene' showed the highest value of the slope of the linear regression, followed by 'TMJ dysfunction' and 'dental implants (indication)'. With this method, it is feasible to detect changes and tendencies in the Dutch dental literature. It permits a selection of clinically relevant topics over a time span. It was concluded that this method may be very useful in the selection of a topic, but should probably be combined with other methods.

  12. When Correction Turns Positive: Processing Corrective Prosody in Dutch

    PubMed Central

    Dimitrova, Diana V.; Stowe, Laurie A.; Hoeks, John C. J.

    2015-01-01

    Current research on spoken language does not provide a consistent picture as to whether prosody, the melody and rhythm of speech, conveys a specific meaning. Perception studies show that English listeners assign meaning to prosodic patterns, and, for instance, associate some accents with contrast, whereas Dutch listeners behave more controversially. In two ERP studies we tested how Dutch listeners process words carrying two types of accents, which either provided new information (new information accents) or corrected information (corrective accents), both in single sentences (experiment 1) and after corrective and new information questions (experiment 2). In both experiments corrective accents elicited a sustained positivity as compared to new information accents, which started earlier in context than in single sentences. The positivity was not modulated by the nature of the preceding question, suggesting that the underlying neural mechanism likely reflects the construction of an interpretation to the accented word, either by identifying an alternative in context or by inferring it when no context is present. Our experimental results provide strong evidence for inferential processes related to prosodic contours in Dutch. PMID:25973607

  13. Summary of the Dutch S3-guidelines on the treatment of psoriasis 2011. Dutch Society of Dermatology and Venereology.

    PubMed

    Zweegers, J; de Jong, E M G J; Nijsten, T E C; de Bes, J; te Booij, M; Borgonjen, R J; van Cranenburgh, O D; van Deutekom, H; van Everdingen, J J E; de Groot, M; Van Hees, C L M; Hulshuizen, H; Koek, M B G; de Korte, W J A; de Korte, J; Lecluse, L L A; Pasch, M C; Poblete-Gutiérrez, P A; Prens, E P; Seyger, M M B; Thio, H B; Torcque, L A; de Vries, A C Q; van de Kerkhof, P C M; Spuls, Ph I

    2014-03-17

    This document provides a summary of the Dutch S3-guidelines on the treatment of psoriasis. These guidelines were finalized in December 2011 and contain unique chapters on the treatment of psoriasis of the face and flexures, childhood psoriasis as well as the patient's perspective on treatment. They also cover the topical treatment of psoriasis, photo(chemo)therapy, conventional systemic therapy and biological therapy.

  14. Internal Structure and Measurement Invariance of the Dutch Eating Behavior Questionnaire (DEBQ) in a (Nearly) Representative Dutch Community Sample.

    PubMed

    Barrada, Juan Ramón; van Strien, Tatjana; Cebolla, Ausiàs

    2016-11-01

    The Dutch Eating Behavior Questionnaire is a widely used instrument for assessment of emotional, external and restrained eating. The aim of the present study is to (i) analyse its internal structure using exploratory structural equation modelling; (ii) to assess its measurement invariance with respect to sex, BMI, age and level of education; and (iii) to evaluate the relations of the factors with these variables. Except that women were slightly over-represented, the sample (n = 2173) closely followed the sociodemographic characteristics of the overall Dutch population. The three theoretical factors that emerged from the analysis were in close correspondence with the three scales for emotional, external and restrained eating. Only two items (item 3 - 'desire to eat when nothing to do…' and item 21 - 'resist delicious food...') presented problematic loadings. The questionnaire showed satisfactory measurement invariance, and expected patterns of mean differences and relations were found. All in all, the results highlight the adequate psychometric properties of the Dutch Eating Behavior Questionnaire. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

  15. Compartmentalisation and zoning: the Dutch perspective.

    PubMed

    Gemmeke, E A A C; Batho, H; Bonbon, E; de Leeuw, P W; Bruschke, C

    2008-12-01

    The aim of the World Organisation for Animal Health (OIE) procedure of compartmentalisation is to contribute to safe trade in live animals and animal products. The fundamental requirement for its application is that the population considered for trade remains epidemiologically separate from populations of higher risk. Compartmentalisation makes use of a functional separation through management, taking into account all relevant epidemiological factors. In this paper, the authors begin by describing current (inter)national developments and actions in this field. Second, some sensitive issues are outlined where one internationally accepted view would help to implement compartmentalisation successfully in international trade. The OIE standards do not contain the procedure for assessing the biosecurity plan, which is crucial. The authors propose the use of a hazard analysis and critical control point system (HACCP) to determine the effectiveness of a biosecurity plan, taking account of all possible risks and potential disease entry points. This could be based on the model of the Codex Alimentarius Commission. Other issues discussed are the outbreak of disease close to a compartment, the role of certification agencies and non-compliance with the biosecurity plan.

  16. A Catskill Flora and Economic Botany, III: Apetalae. Including the Poplars, Willows, Hickories, Birches, Beeches, Oaks, Elms, Nettles, Sorrels, Docks, and Smartweeds. Bulletin No. 443, New York State Museum.

    ERIC Educational Resources Information Center

    Brooks, Karl L.

    This compendium deals with the ecology and economic importance of the poplars, willows, hickories, birches, beeches, oaks, elms, nettles, sorrels, docks, and smartweeds growing in New York's Catskills. Provided are keys for identifying each plant to species by flowers, foliage, or winter buds. A line drawing accompanies a summary of basic data…

  17. Adaptation of a difficult-to-manage asthma programme for implementation in the Dutch context: a modified e-Delphi.

    PubMed

    Honkoop, Persijn J; Pinnock, Hilary; Kievits-Smeets, Regien M M; Sterk, Peter J; Dekhuijzen, P N Richard; In 't Veen, Johannes C C M

    2017-02-09

    Patients with difficult-to-manage asthma represent a heterogeneous subgroup of asthma patients who require extensive assessment and tailored management. The International Primary Care Respiratory Group approach emphasises the importance of differentiating patients with asthma that is difficult to manage from those with severe disease. Local adaptation of this approach, however, is required to ensure an appropriate strategy for implementation in the Dutch context. We used a modified three-round e-Delphi approach to assess the opinion of all relevant stakeholders (general practitioners, pulmonologists, practice nurses, pulmonary nurses and people with asthma). In the first round, the participants were asked to provide potentially relevant items for a difficult-to-manage asthma programme, which resulted in 67 items. In the second round, we asked participants to rate the relevance of specific items on a seven-point Likert scale, and 46 items were selected as relevant. In the third round, the selected items were categorised and items were ranked within the categories according to relevance. Finally, we created the alphabet acronym for the categories 'the A-I of difficult-to-manage asthma' to resonate with an established Dutch 'A-E acronym for determining asthma control'. This should facilitate implementation of this programme within the existing structure of educational material on asthma and chronic obstructive pulmonary disease (COPD) in primary care, with potential for improving management of difficult-to-manage asthma. Other countries could use a similar approach to create a locally adapted version of such a programme.

  18. 75 FR 48736 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Dutch Interiors”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Dutch Interiors'' SUMMARY..., I hereby determine that the objects to be included in the exhibition ``Mir : The Dutch...

  19. The debate about acclimatization in the Dutch East Indies (1840-1860).

    PubMed Central

    de Knecht-van Eekelen, A.

    2000-01-01

    Around the middle of the nineteenth century, conflicting views were put forward on the influence of climate on health and disease in the Dutch East Indies. In this part of the world, old Hippocratic ideas influenced views on the cause of disease much longer than in the Netherlands. Moreover, Brunonian theories--which had been discarded in the Netherlands--fitted the discussion about the effect of temperature on the body. Additionally, scientific medicine was introduced. Scientific methods, such as the collection of meteorological and statistical data, were promoted by a small group of military health officers. However, the use of scientific data did not guarantee a clear-cut opinion on the causes of disease. Numbers proved as disputable as other, less objective, medical observations. Mortality statistics and numbers of patients especially were used as arguments in various discussions. The example of Bosch, who changed his views on the dangers of tropical climate, demonstrates that statistics could be used for different purposes. At first, in his position as General Inspector, he used them as an argument to provide better care for the military personnel; later, when retired and a civilian, he used them as justification for colonization in relation to an intended improvement of the living conditions of the natives. The dangers of tropical climate for the health of Europeans were played down as soon as other--primarily economic--motives for living in the tropics became strong enough. PMID:11769938

  20. Detection of early blight and late blight diseases on tomato leaves using hyperspectral imaging

    PubMed Central

    Xie, Chuanqi; Shao, Yongni; Li, Xiaoli; He, Yong

    2015-01-01

    This study investigated the potential of using hyperspectral imaging for detecting different diseases on tomato leaves. One hundred and twenty healthy, one hundred and twenty early blight and seventy late blight diseased leaves were selected to obtain hyperspectral images covering spectral wavelengths from 380 to 1023 nm. An extreme learning machine (ELM) classifier model was established based on full wavelengths. Successive projections algorithm (SPA) was used to identify the most important wavelengths. Based on the five selected wavelengths (442, 508, 573, 696 and 715 nm), an ELM model was re-established. Then, eight texture features (mean, variance, homogeneity, contrast, dissimilarity, entropy, second moment and correlation) based on gray level co-occurrence matrix (GLCM) at the five effective wavelengths were extracted to establish detection models. Among the models which were established based on spectral information, all performed excellently with the overall classification accuracy ranging from 97.1% to 100% in testing sets. Among the eight texture features, dissimilarity, second moment and entropy carried most of the effective information with the classification accuracy of 71.8%, 70.9% and 69.9% in the ELM models. The results demonstrated that hyperspectral imaging has the potential as a non-invasive method to identify early blight and late blight diseases on tomato leaves. PMID:26572857

  1. Detection of early blight and late blight diseases on tomato leaves using hyperspectral imaging.

    PubMed

    Xie, Chuanqi; Shao, Yongni; Li, Xiaoli; He, Yong

    2015-11-17

    This study investigated the potential of using hyperspectral imaging for detecting different diseases on tomato leaves. One hundred and twenty healthy, one hundred and twenty early blight and seventy late blight diseased leaves were selected to obtain hyperspectral images covering spectral wavelengths from 380 to 1023 nm. An extreme learning machine (ELM) classifier model was established based on full wavelengths. Successive projections algorithm (SPA) was used to identify the most important wavelengths. Based on the five selected wavelengths (442, 508, 573, 696 and 715 nm), an ELM model was re-established. Then, eight texture features (mean, variance, homogeneity, contrast, dissimilarity, entropy, second moment and correlation) based on gray level co-occurrence matrix (GLCM) at the five effective wavelengths were extracted to establish detection models. Among the models which were established based on spectral information, all performed excellently with the overall classification accuracy ranging from 97.1% to 100% in testing sets. Among the eight texture features, dissimilarity, second moment and entropy carried most of the effective information with the classification accuracy of 71.8%, 70.9% and 69.9% in the ELM models. The results demonstrated that hyperspectral imaging has the potential as a non-invasive method to identify early blight and late blight diseases on tomato leaves.

  2. Eight Years of Specialist Training of Dutch Intellectual Disability Physicians: Results of Scientific Research Education

    ERIC Educational Resources Information Center

    Evenhuis, Heleen M.; Penning, Corine

    2009-01-01

    Training in scientific research methods and skills is a vital part of Dutch specialist training in intellectual disability medicine. The authors evaluated results of such training at one Dutch university medical facility that had an obligatory research program involving projects conducted by the physicians-in-training (topics, teamwork, acquired…

  3. Zertifikat Niederlaendisch: Examen en getuigschrift Nederlands als vreemde taal (Certificate in Dutch)

    ERIC Educational Resources Information Center

    Beersmans, Frans; Sudhoelter, Juergen

    1976-01-01

    An interim report on preparations for designing an examination in Dutch. The "unit-credit system" proposed by the Council of Europe is being used. The Dutch certificate will be comparable to the certificates given by the British Council and by the People's Universities. Sample portions are given. (Text is in German.) (IFS/WGA)

  4. Modality, Infinitives, and Finite Bare Verbs in Dutch and English Child Language

    ERIC Educational Resources Information Center

    Blom, Elma

    2007-01-01

    This article focuses on the meaning of nonfinite clauses ("root infinitives") in Dutch and English child language. I present experimental and naturalistic data confirming the claim that Dutch root infinitives are more often modal than English root infinitives. This cross-linguistic difference is significantly smaller than previously assumed,…

  5. On-Line Access to Linguistically Annotated Text Corpora of Dutch via Internet.

    ERIC Educational Resources Information Center

    Kruyt, J. G.; Raaijmakers, S. A.; van der Kamp, P. H. J.; van Strien, R. J.

    Corpora of present-day Dutch developed by the Institute for Dutch Lexicology include two linguistically annotated corpora that can be accessed via Internet: a 5-million word corpus covering a variety of topics and text types, and a 27-million word newspaper corpus. The texts of both were acquired in machine-readable form and have been lemmatized…

  6. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Newtown Creek, Dutch Kills, English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following...

  7. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Newtown Creek, Dutch Kills, English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following...

  8. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Newtown Creek, Dutch Kills, English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following...

  9. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Newtown Creek, Dutch Kills, English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following...

  10. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Newtown Creek, Dutch Kills, English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following...

  11. A Comparison of Dutch and US Teachers' Perceptions of the Incidence and Management of ADHD

    ERIC Educational Resources Information Center

    Havey, J. Michael

    2007-01-01

    Dutch and US teachers were questioned about their perceptions of the incidence and causes of ADHD, as well as their views of appropriate treatments. Dutch teachers were more likely than US teachers to think the etiology of the disorder lay in biochemistry, while US teachers were more likely to believe in a combination of environmental and…

  12. In the Shadow of Tolerance: The Discursive Context of Dutch-Born Muslim Youth

    ERIC Educational Resources Information Center

    Zaal, Mayida

    2014-01-01

    Despite a public discourse on tolerance, anxiety about immigrants, Islam and the preservation of Dutch values has amplified fear of Muslim youth in the Netherlands. In this context, Dutch-born Muslim youth endure social and systemic discrimination that affects all aspects of their futures, including available educational opportunities and…

  13. From Noun to Intensifier: Massa and Massa's in Flemish Varieties of Dutch

    ERIC Educational Resources Information Center

    De Clerck, Bernard; Colleman, Timothy

    2013-01-01

    In this paper a case of synchronic layering is examined in which Dutch "massa" ("mass") and plural "massa's" ("masses") are attested with lexical uses as a collective noun, quantifying uses ("a large quantity of") and intensifying uses ("very")--with plural "massa's" only--in some Flemish varieties of Dutch. Against the background of…

  14. Production and Processing of Subject-Verb Agreement in Monolingual Dutch Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Blom, Elma; Vasic, Nada; de Jong, Jan

    2014-01-01

    Purpose: In this study, the authors investigated whether errors with subject-verb agreement in monolingual Dutch children with specific language impairment (SLI) are influenced by verb phonology. In addition, the productive and receptive abilities of Dutch acquiring children with SLI regarding agreement inflection were compared. Method: An SLI…

  15. Phoneme Awareness, Vocabulary and Word Decoding in Monolingual and Bilingual Dutch Children

    ERIC Educational Resources Information Center

    Janssen, Marije; Bosman, Anna M. T.; Leseman, Paul P. M.

    2013-01-01

    The aim of this study was to investigate whether bilingually raised children in the Netherlands, who receive literacy instruction in their second language only, show an advantage on Dutch phoneme-awareness tasks compared with monolingual Dutch-speaking children. Language performance of a group of 47 immigrant first-grade children with various…

  16. Home Language and Language Proficiency; A Large-Scale Longitudinal Study in Dutch Primary Schools.

    ERIC Educational Resources Information Center

    Driessen, Geert; van der Slik, Frans; De Bot, Kees

    2002-01-01

    Reports on a large-scale longitudinal study into the development of language proficiency of Dutch primary school children aged 7-10. Data on language proficiency and a range of background variables were analyzed. Results suggest that while immigrant children develop their language skill in Dutch considerably over 2 years, they are nonetheless…

  17. A 16-Year Longitudinal Study of Language Attrition in Dutch Immigrants in Australia.

    ERIC Educational Resources Information Center

    de Bot, Kees; Clyne, Michael

    1994-01-01

    Speech material gathered from Dutch-English bilinguals in Australia questioned in 1971 and 1987 was analyzed, showing no evidence of attrition in Dutch. It is concluded that first-language attrition does not necessarily occur in an immigrant setting and that immigrants who maintain their language in the first years of their stay will likely remain…

  18. Development of a double plasma gun device for investigation of effects of vapor shielding on erosion of PFC materials under ELM-like pulsed plasma bombardment

    NASA Astrophysics Data System (ADS)

    Sakuma, I.; Iwamoto, D.; Kitagawa, Y.; Kikuchi, Y.; Fukumoto, N.; Nagata, M.

    2012-10-01

    It is considered that thermal transient events such as type I edge localized modes (ELMs) could limit the lifetime of plasma-facing components (PFCs) in ITER. We have investigated surface damage of tungsten (W) materials under transient heat and particle loads by using a magnetized coaxial plasma gun (MCPG) device at University of Hyogo. The capacitor bank energy for the plasma discharge is 144 kJ (2.88 mF, 10 kVmax). Surface melting of a W material was clearly observed at the energy density of ˜2 MJ/m2. It is known that surface melting and evaporation during a transient heat load could generate a vapor cloud layer in front of the target material [1]. Then, the subsequent erosion could be reduced by the vapor shielding effect. In this study, we introduce a new experiment using two MCPG devices (MCPG-1, 2) to understand vapor shielding effects of a W surface under ELM-like pulsed plasma bombardment. The capacitor bank energy of MCPG-2 is almost same as that of MCPG-1. The second plasmoid is applied with a variable delay time after the plasmoid produced by MCPG-1. Then, a vapor cloud layer could shield the second plasma load. To verify the vapor shielding effects, surface damage of a W material is investigated by changing the delay time. In the conference, the preliminary experimental results will be shown.[4pt] [1] A. Hassanein et al., J. Nucl. Mater. 390-391, pp. 777-780 (2009).

  19. Do Mothers Have the Right to Bring up Their Own Children? How Facts Do Not Determine (Dutch) Government Policy

    ERIC Educational Resources Information Center

    Allewijn, Ellen

    2010-01-01

    The Dutch government has a double moral message for Dutch parents. On the one hand, they expect mothers to work more hours outside the home; on the other hand, they expect parents to perform better in their parental tasks. New research shows again that in spite of all stimulation measures, Dutch women with children prefer their part-time jobs, and…

  20. Social Integration and Religious Identity Expression among Dutch Muslims: The Role of Minority and Majority Group Contact

    ERIC Educational Resources Information Center

    Maliepaard, Mieke; Phalet, Karen

    2012-01-01

    Against the background of contrasting religious versus secular norms in immigrant communities and in Dutch society, this study examines how religious identity expression is related to the social integration of Dutch Muslims within (a) Turkish or Moroccan minority groups and (b) Dutch majority groups. Using nationally representative survey data (N…

  1. 75 FR 54692 - Culturally Significant Objects Imported for Exhibition Determinations: “Miró: The Dutch Interiors”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Mir : The Dutch Interiors'' ACTION... ''Mir : The Dutch Interiors.'' The reference notice is corrected to accommodate an additional object to... determine that the additional object to be included in the exhibition ``Mir : The Dutch...

  2. The Prevalence of Tooth Wear in the Dutch Adult Population

    PubMed Central

    Wetselaar, Peter; Vermaire, Jan H.; Visscher, Corine M.; Lobbezoo, Frank; Schuller, Annemarie A.

    2016-01-01

    This study aimed to assess the prevalence of tooth wear in different age groups of the Dutch adult population and to determine this tooth wear distribution by gender, socioeconomic class, and type of teeth. Results were compared with the outcomes of a previous study in a comparable population. As part of a comprehensive investigation of the oral health of the general Dutch adult population in 2013, tooth wear was assessed among 1,125 subjects in the city of ‘s-Hertogenbosch. The data collected were subjected to stratified analysis by 5 age groups (25-34, 35-44, 45-54, 55-64, and 65-74 years), gender, socioeconomic class, and type of teeth. Tooth wear was assessed using a 5-point ordinal occlusal/incisal grading scale. The number of teeth affected was higher in older age groups. Men showed more tooth wear than women, and subjects with low socioeconomic status (low SES) showed on average higher scores than those with high SES. Tooth wear prevalence found in this study was higher in all age groups than in the previous study. The present study found prevalences of 13% for mild tooth wear and 80% for moderate tooth wear, leading to the conclusion that these are common conditions in the Dutch adult population. Severe tooth wear (prevalence 6%) may however be characterized as rare. A tendency was found for there to be more tooth wear in older age groups, in men as compared with women, in persons with lower SES, and in the present survey as compared with the previous one. PMID:27694757

  3. Dutch Minister of Science Visits ESO Facilities in Chile

    NASA Astrophysics Data System (ADS)

    2005-05-01

    Mrs. Maria van der Hoeven, the Dutch Minister of Education, Culture and Science, who travelled to the Republic of Chile, arrived at the ESO Paranal Observatory on Friday afternoon, May 13, 2005. The Minister was accompanied, among others, by the Dutch Ambassador to Chile, Mr. Hinkinus Nijenhuis, and Mr. Cornelis van Bochove, the Dutch Director of Science. The distinguished visitors were able to acquaint themselves with one of the foremost European research facilities, the ESO Very Large Telescope (VLT), during an overnight stay at this remote site, and later, with the next major world facility in sub-millimetre and millimetre astronomy, the Atacama Large Millimeter Array (ALMA). At Paranal, the guests were welcomed by the ESO Director General, Dr. Catherine Cesarsky; the ESO Council President, Prof. Piet van der Kruit; the ESO Representative in Chile, Prof. Felix Mirabel; the Director of the La Silla Paranal Observatory, Dr. Jason Spyromilio; by one of the Dutch members of the ESO Council, Prof. Tim de Zeeuw; by the renowned astrophysicist from Leiden, Prof. Ewine van Dishoek, as well as by ESO staff members. The visitors were shown the various high-tech installations at the observatory, including many of the large, front-line VLT astronomical instruments that have been built in collaboration between ESO and European research institutes. Explanations were given by ESO astronomers and engineers and the Minister gained a good impression of the wide range of exciting research programmes that are carried out with the VLT. Having enjoyed the spectacular sunset over the Pacific Ocean from the Paranal deck, the Minister visited the VLT Control Room from where the four 8.2-m Unit Telescopes and the VLT Interferometer (VLTI) are operated. Here, the Minister was invited to follow an observing sequence at the console of the Kueyen (UT2) and Melipal (UT3) telescopes. "I was very impressed, not just by the technology and the science, but most of all by all the people involved

  4. Patient safety in Dutch primary care: a study protocol

    PubMed Central

    2010-01-01

    Background Insight into the frequency and seriousness of potentially unsafe situations may be the first step towards improving patient safety. Most patient safety attention has been paid to patient safety in hospitals. However, in many countries, patients receive most of their healthcare in primary care settings. There is little concrete information about patient safety in primary care in the Netherlands. The overall aim of this study was to provide insight into the current patient safety issues in Dutch general practices, out-of-hours primary care centres, general dental practices, midwifery practices, and allied healthcare practices. The objectives of this study are: to determine the frequency, type, impact, and causes of incidents found in the records of primary care patients; to determine the type, impact, and causes of incidents reported by Dutch healthcare professionals; and to provide insight into patient safety management in primary care practices. Design and methods The study consists of three parts: a retrospective patient record study of 1,000 records per practice type was conducted to determine the frequency, type, impact, and causes of incidents found in the records of primary care patients (objective one); a prospective component concerns an incident-reporting study in each of the participating practices, during two successive weeks, to determine the type, impact, and causes of incidents reported by Dutch healthcare professionals (objective two); to provide insight into patient safety management in Dutch primary care practices (objective three), we surveyed organizational and cultural items relating to patient safety. We analysed the incidents found in the retrospective patient record study and the prospective incident-reporting study by type of incident, causes (Eindhoven Classification Model), actual harm (severity-of-outcome domain of the International Taxonomy of Medical Errors in Primary Care), and probability of severe harm or death. Discussion

  5. Practice variation in the Dutch long-term care and the role of supply-sensitive care: Is access to the Dutch long-term care equitable?

    PubMed

    Duell, Daisy; Koolman, Xander; Portrait, France

    2017-03-02

    Universal access and generous coverage are important goals of the Dutch long-term care (LTC) system. It is a legal requirement that everyone eligible for LTC should be able to receive it. Institutional care (IC) made up for 90% of Dutch LTC spending. To investigate whether access to IC is as equitable as the Dutch government aspires, we explored practice variation in entitlements to IC across Dutch regions. We used a unique dataset that included all individual applications for Dutch LTC in January 2010-December 2013 (N = 3,373,358). This dataset enabled an accurate identification of the need for care. We examined the local variation in the probability of being granted long-term IC and in the intensity of the care granted given that individuals have applied for LTC. We also investigated whether the variation observed was related to differences in the local availability of care facilities. Although our analyses indicated the presence of some practice variation, its magnitude was very small by national and international standards (up to 3%). Only a minor part of the practice variation could be accounted for by local supply differences in care facilities. Overall, we conclude that, unlike many other developed countries, the Dutch system ensured equitable access to long-term IC.

  6. Functional Analysis Helps to Define KCNC3 Mutational Spectrum in Dutch Ataxia Cases

    PubMed Central

    Fokkens, Michiel R.; Meijer, Michel; Boerrigter, Melissa; Verschuuren-Bemelmans, Corien C.; Kremer, Berry P. H.; van de Warrenburg, Bart P.; Dooijes, Dennis; Boddeke, Erik; Sinke, Richard J.; Verbeek, Dineke S.

    2015-01-01

    Spinocerebellar ataxia type 13 (SCA13) is an autosomal dominantly inherited neurodegenerative disorder of the cerebellum caused by mutations in the voltage gated potassium channel KCNC3. To identify novel pathogenic SCA13 mutations in KCNC3 and to gain insights into the disease prevalence in the Netherlands, we sequenced the entire coding region of KCNC3 in 848 Dutch cerebellar ataxia patients with familial or sporadic origin. We evaluated the pathogenicity of the identified variants by co-segregation analysis and in silico prediction followed by biochemical and electrophysiological studies. We identified 19 variants in KCNC3 including 2 non-coding, 11 missense and 6 synonymous variants. Two missense variants did not co-segregate with the disease and were excluded as potentially disease-causing mutations. We also identified the previously reported p.R420H and p.R423H mutations in our cohort. Of the remaining 7 missense variants, functional analysis revealed that 2 missense variants shifted Kv3.3 channel activation to more negative voltages. These variations were associated with early disease onset and mild intellectual disability. Additionally, one other missense variant shifted channel activation to more positive voltages and was associated with spastic ataxic gait. Whereas, the remaining missense variants did not change any of the channel characteristics. Of these three functional variants, only one variant was in silico predicted to be damaging and segregated with disease. The other two variants were in silico predicted to be benign and co-segregation analysis was not optimal or could only be partially confirmed. Therefore, we conclude that we have identified at least one novel pathogenic mutation in KCNC3 that cause SCA13 and two additionally potential SCA13 mutations. This leads to an estimate of SCA13 prevalence in the Netherlands to be between 0.6% and 1.3%. PMID:25756792

  7. The educational needs of people with systemic sclerosis: a cross-sectional study using the Dutch version of the Educational Needs Assessment Tool (D-ENAT).

    PubMed

    Schouffoer, Anne; Ndosi, Mwidimi E; Vliet Vlieland, Thea P M; Meesters, Jorit J L

    2016-02-01

    The Dutch Educational Needs Assessment Tool (D-ENAT) systematically assesses educational needs of patients with rheumatic diseases. The present study aims to describe the educational needs of Dutch patients with systemic sclerosis (SSc). The D-ENAT was sent to 155 SSc patients registered at the outpatient clinic of a university hospital. The D-ENAT consists of 39 items in seven domains. "Each domain has different number of items therefore we normalized each domain score: (domain score/maximum) × 100) and expressed in percentage to enable comparisons between domains." A total D-ENAT score (0-156) is calculated by summing all 39 items. In addition, age, disease duration, gender, educational level, present information need (yes/no) and information need (1-4; wanting to know nothing-everything) were recorded. Univariate regression analysis was used to examine factors associated with the D-ENAT scores. The response rate was 103 out of 155 (66 %). The mean % of educational needs scores (0-100 %; lowest-highest) were 49 % for "D-ENAT total score," 46 % for "Managing pain," 41 % for "Movement," 43 % for "Feelings," 59 % for "Disease process," 44 % for "Treatments from health professionals," 61 % for "Self-help measures" and 51 % for "Support systems." No associations between the D-ENAT total score and age, disease duration, gender and educational level were found. The D-ENAT demonstrated its ability to identify educational needs of Dutch SSc patients. SSc patients demonstrated substantial educational needs, especially in the domains: "Disease process" and "Self-help measures." The validity and practical applicability of the D-ENAT to make an inventory of SSc patients' educational needs require further investigation.

  8. Herd management practices associated with paratuberculosis seroprevalence in Dutch dairy herds.

    PubMed

    Muskens, J; Elbers, A R W; van Weering, H J; Noordhuizen, J P T M

    2003-10-01

    We describe the paratuberculosis management practices applied in dairy herds in the Netherlands. The findings from paratuberculosis seronegative and seropositive herds were compared to discover possible risk factors. In total, 370 randomly selected herds with > or =20 dairy cows were surveyed. A questionnaire was used to collect data on current and previous paratuberculosis management practices. All cattle aged > or =3 years were serologically tested for paratuberculosis using an enzyme-linked immunosorbent assay. Herds with >33 tested cattle, of which only one was seropositive, were excluded to reduce the risk of including false-positive herds in the analysis. A comparison of the management data of the seronegative herds (n = 166) and the seropositive herds (n = 143) showed that in both groups important management measures for the prevention of paratuberculosis, such as calving in a cleaned calving area, removing the calf immediately after birth, and feeding paratuberculosis non-suspect roughage to calves, were used only rarely. However, such measures should be regarded as the critical first step to control the disease and/or reduce its prevalence. Using univariable analysis, four factors were statistically different between seronegative and seropositive herds: herd size, cows with clinical signs of paratuberculosis, prompt selling of clinically diseased cattle and feeding milk replacer. Using a multivariable logistic regression model, only herd size was a significantly different factor. These results indicate that most of the paratuberculosis preventive management measures were executed on these Dutch dairy farms only to a limited extent.

  9. Oligomerization of beta-amyloid of the Alzheimer's and the Dutch-cerebral-haemorrhage types.

    PubMed Central

    Sian, A K; Frears, E R; El-Agnaf, O M; Patel, B P; Manca, M F; Siligardi, G; Hussain, R; Austen, B M

    2000-01-01

    A novel ELISA has been developed which detects oligomerization of beta-amyloid (A beta). Oligomerization, fibrillization and neurotoxicity of native A beta associated with Alzheimer's disease (AD) type has been compared with E22Q A beta (amyloid beta-protein containing residues 1--40 with the native Glu at residue 22 changed to Gln) implicated in Dutch cerebral haemorrhage disease. Solutions of A beta rapidly yield soluble oligomers in a concentration-dependent manner, which are detected by the ELISA, and by size-exclusion gel chromatography. Conformational changes from disordered to beta-sheet occur more slowly than oligomerization, and fibrils are produced after prolonged incubation. The E22Q A beta oligomerizes, changes conformation and fibrillizes more rapidly than the native form and produces shorter stubbier fibrils. Aged fibrillar preparations of E22Q A beta are more potent than aged fibrils of native A beta in inducing apoptotic changes and toxic responses in human neuroblastoma cell lines, whereas low-molecular-mass oligomers in briefly incubated solutions are much less potent. The differences in the rates of oligomerization of the two A beta forms, their conformational behaviour over a range of pH values, and NMR data reported elsewhere, are consistent with a molecular model of oligomerization in which strands of A beta monomers initially overcome charge repulsion to form dimers in parallel beta-sheet arrangement, stabilized by intramolecular hydrophobic interactions, with amino acids of adjacent chains in register. PMID:10861242

  10. Dutch Consumers' Willingness to Pay for Broiler Welfare.

    PubMed

    Mulder, Machiel; Zomer, Sigourney

    2017-02-06

    This article analyzes Dutch consumers' willingness to pay (WTP) for the welfare of broiler chickens and the consequences for nonhuman animal welfare policies. Using data from a discrete-choice experiment and a random parameter logit model, this study showed that consumers particularly value opportunities for outdoor access and the method used for anesthesia before slaughter. The WTP was also positively related to the number of consumers buying the same product, indicating that they experience the public-good dilemma. Moreover, the WTP was higher if consumers knew that animal welfare practices were subject to public or collective supervision. Women, people with more education, those with higher income, and nonreligious people had relatively high WTP values. For 87.5% of the respondents, the WTP exceeded the price difference between a broiler with a higher level of animal welfare and a regular chicken. The findings suggest that the Dutch market for broiler chickens can be improved by raising consumer confidence in the labeling system.

  11. Lexical frequency and acoustic reduction in spoken Dutch

    NASA Astrophysics Data System (ADS)

    Pluymaekers, Mark; Ernestus, Mirjam; Baayen, R. Harald

    2005-10-01

    This study investigates the effects of lexical frequency on the durational reduction of morphologically complex words in spoken Dutch. The hypothesis that high-frequency words are more reduced than low-frequency words was tested by comparing the durations of affixes occurring in different carrier words. Four Dutch affixes were investigated, each occurring in a large number of words with different frequencies. The materials came from a large database of face-to-face conversations. For each word containing a target affix, one token was randomly selected for acoustic analysis. Measurements were made of the duration of the affix as a whole and the durations of the individual segments in the affix. For three of the four affixes, a higher frequency of the carrier word led to shorter realizations of the affix as a whole, individual segments in the affix, or both. Other relevant factors were the sex and age of the speaker, segmental context, and speech rate. To accommodate for these findings, models of speech production should allow word frequency to affect the acoustic realizations of lower-level units, such as individual speech sounds occurring in affixes.

  12. [Multiresistant Brachyspira hyodysenteriae in a Dutch sow herd].

    PubMed

    Duinhof, T F; Dierikx, C M; Koene, M G J; van Bergen, M A P; Mevius, D J; Veldman, K T; van Beers-Schreurs, H M G; de Winne, R T J A

    This case study describes the isolation ofa multiresistant strain ofBrachyspira hyodysenteriae in April 2007 in a Dutch sow herd with recurrent diarrhoea. Examination of faecal samples taken from 7-month-old breeding gilts with diarrhoea revealed the presence of resistance against tiamulin, lincomycin, tylosin, doxycycline, and tylvalosin (the active substance in Aivlosin) in four of five samples. Tiamulin resistance has not been reported in The Netherlands before. The repeated use of tiamulin on the affected farm was assumed to be the main cause of the development of resistance to the drug. The farmer was advised to adopt a medication strategy and to implement management practices that would prevent an ongoing cycle of infection on the farm. It is important that the Dutch swine industry appreciates that tiamulin-resistant strains of B. hyodysenteriae may be found on other farms as well. The appropriate and prudent use of antibiotics is essential in order to prevent the development of resistance against the last option left to cure B. hyodysenteriae infections: valnemulin.

  13. The Importance of Relationships with Parents and Best Friends for Adolescents' Romantic Relationship Quality: Differences between Indigenous and Ethnic Dutch Adolescents

    ERIC Educational Resources Information Center

    Ha, Thao; Overbeek, Geertjan; de Greef, Marieke; Scholte, Ron H. J.; Engels, Rutger C. M. E.

    2010-01-01

    This study examined how the quality of relationships with parents and friends were related to intimacy, commitment, and passion in adolescents' romantic relationships for indigenous Dutch and ethnic Dutch adolescents. Self-report survey data were used from 444 (88.9%) indigenous Dutch and 55 (11.1%) ethnic Dutch adolescents between 12 and 18 years…

  14. Notes from Batavia, the Europeans' graveyard: the nineteenth-century debate on acclimatization in the Dutch East Indies.

    PubMed

    Pols, Hans

    2012-01-01

    Since the advent of European colonial expansion, medical theories of acclimatization have been inextricably related to convictions about the possibility and desirability of white settlement in the colonies, and political ideas of colonial governance. Before 1800, acclimatization theories emphasized the inherent flexibility of the human constitution and its ability to adapt to new environments. During the first half of the nineteenth century, European theorists came to highlight the vulnerability of white Europeans in the tropics to disease, degeneration, and death instead. They consequently argued that white settlement in the tropics was impossible and inadvisable. European physicians in the British and French colonies presented similar views. By contrast, their colleagues in the Dutch East Indies remained optimistic. They associated themselves with the colonial European settler community and shared their grievances against autocratic colonial rule. They presented medical theories which related acclimatization to prudent behavior, morality, and proper management of the environment, thereby downplaying the significance of climate and high temperatures. During the following decades, their views on acclimatization were transferred to the Netherlands, where they were deployed as an argument against the cultivation system, the then-current approach of colonial governance, which emphasized the trade of cash crops grown by the indigenous population, severely limited European settlement, and curtailed the rights of Europeans living in the Indies. Throughout the nineteenth century, the influence of climate and the possibility of acclimatization became recurring themes in debates about colonial governance in both the Dutch East Indies and the Netherlands.

  15. Medicalization and obstetric care: an analysis of developments in Dutch midwifery.

    PubMed

    Smeenk, Anke D J; ten Have, Henk A M J

    2003-01-01

    The Dutch system of obstetric care is often recommended for midwife-attended births, the high number of home deliveries, and the low rate of intervention during pregnancy and labour. In this contribution, the question is addressed whether processes of medicalization can be demonstrated in the Dutch midwife practice. Medicalization of pregnancy and childbirth is often criticized because it creates dependency on the medical system and infringement of the autonomy of pregnant women. It is concluded that medicalization is present in the practice of Dutch independent midwives, however it is less clear and outspoken than in hospital policies.

  16. Intoxication and criminal responsibility in Dutch criminal Law.

    PubMed

    van Kalmthout, A

    1998-09-01

    This article deals with the question in how far an offence committed in the Netherlands under the influence of alcohol or other drugs can be imputed to the offender. Unlike many other countries the Dutch Penal Code does not contain specific provisions with respect to the criminal liability of addicted or intoxicated offenders. In principle, they are held responsible for their offences, even when the dolus or culpa is absent at the moment they commit their offence. Doctrine and jurisprudence found this liability on the principle of 'culpa/dolus in causa', by accepting an anterior dolus or culpa, which is situated at the moment the offender takes alcohol or other drugs. As is shown in this article, the - nondogmatic - interpretation of this culpa in causa doctrine leaves hardly any space for a claim to impunity.

  17. The Time Course of Verb Processing in Dutch Sentences

    PubMed Central

    Shapiro, Lewis P.; Wester, Femke; Swinney, David A.; Bastiaanse, Roelien

    2012-01-01

    The verb has traditionally been characterized as the central element in a sentence. Nevertheless, the exact role of the verb during the actual ongoing comprehension of a sentence as it unfolds in time remains largely unknown. This paper reports the results of two Cross-Modal Lexical Priming (CMLP) experiments detailing the pattern of verb priming during on-line processing of Dutch sentences. Results are contrasted with data from a third CMLP experiment on priming of nouns in similar sentences. It is demonstrated that the meaning of a matrix verb remains active throughout the entire matrix clause, while this is not the case for the meaning of a subject head noun. Activation of the meaning of the verb only dissipates upon encountering a clear signal as to the start of a new clause. PMID:19452278

  18. [Dutch Zoological Gardens (until 1940) in historical context].

    PubMed

    Zwart, P

    2009-01-01

    The history of the zoological gardens is an example of transformation through the ages; it is one of the ways men are dealing with their enviroment. Through the ages there were six reasons to keep wild animals: (1) Religion; 2. Power and Richness; (3) To get acquainted with animals (from tropical regions); (4) Study and Education; (5) Amusement and (6) Preservation of the species. The first Dutch "zoos", of the Dukes of Guelders in the 14th and of the stadholders in the 19th century, can serve as examples of the will to demonstrate power and richness. The Amsterdam Zoological Garden, "Artis", the zoological gardens of Rotterdam and of The Hague were founded for reasons of study and/ or education. Burgers' Dierenpark (Arnhem), Ouwehand's Dierenpark (Rhenen), Dierenpark Emmen en Dierenpark Wassenaar originated as leisure activities of their owners.

  19. Emotional, external, restrained eating and overweight in Dutch adolescents.

    PubMed

    Snoek, Harriëtte M; van Strien, Tatjana; Janssens, Jan M A M; Engels, Rutger C M E

    2007-02-01

    The purpose of this study was to determine how emotional, external and restrained eating behavior and other health-related lifestyle factors were associated with being overweight in adolescents. Moreover, demographic and ethnic differences in eating behavior have been examined. The respondents were 10,087 Dutch adolescents aged 11-16 years (M= 13.0, SD= 0.8). Self-reported eating behavior was measured with the DEBQ. Health-related lifestyle was determined by physical activity, breakfasting, fruit consumption and snacking. High restrained, and low external eating were positively associated with being overweight, whereas no significant association between emotional eating and being overweight was found for girls, and a negative association for boys. Adolescents who ate breakfast on a daily basis were less likely to be overweight than those who ate breakfast irregularly or never. Being overweight was positively associated with fruit consumption for girls and negatively with physical activity for boys.

  20. Narcissistic Personality Inventory: structure of the adapted Dutch version.

    PubMed

    Barelds, Dick P H; Dijkstra, Pieternel

    2010-04-01

    The present study examined the structure of a Dutch adaptation of the 40-item Narcissistic Personality Inventory (Raskin & Terry, 1988) in a community sample (n = 460) and a student sample (n = 515). Altering the response format of the NPI to a Likert-scale had no apparent effect on the responses. Confirmatory factor analyses supported neither the four-factor structure reported by Emmons (1984), nor the seven-factor structure reported by Raskin and Terry (1988). Instead, exploratory factor analyses supported either a single-factor solution (general narcissism), or a two-factor solution (Authority/Power and Self-Admiration). The validity of the NPI was supported by its relations with sex, age, personality, self-esteem, shame, guilt and social desirability.