Assessment of knowledge transfer in the context of biomechanics
NASA Astrophysics Data System (ADS)
Hutchison, Randolph E.
The dynamic act of knowledge transfer, or the connection of a student's prior knowledge to features of a new problem, could be considered one of the primary goals of education. Yet studies highlight more instances of failure than success. This dissertation focuses on how knowledge transfer takes place during individual problem solving, in classroom settings and during group work. Through the lens of dynamic transfer, or how students connect prior knowledge to problem features, this qualitative study focuses on a methodology to assess transfer in the context of biomechanics. The first phase of this work investigates how a pedagogical technique based on situated cognition theory affects students' ability to transfer knowledge gained in a biomechanics class to later experiences both in and out of the classroom. A post-class focus group examined events the students remembered from the class, what they learned from them, and how they connected them to later relevant experiences inside and outside the classroom. These results were triangulated with conceptual gains evaluated through concept inventories and pre- and post- content tests. Based on these results, the next two phases of the project take a more in-depth look at dynamic knowledge transfer during independent problem-solving and group project interactions, respectively. By categorizing prior knowledge (Source Tools), problem features (Target Tools) and the connections between them, results from the second phase of this study showed that within individual problem solving, source tools were almost exclusively derived from "propagated sources," i.e. those based on an authoritative source. This differs from findings in the third phase of the project, in which a mixture of "propagated" sources and "fabricated" sources, i.e. those based on student experiences, were identified within the group project work. This methodology is effective at assessing knowledge transfer in the context of biomechanics through evidence of the ability to identify differing patterns of how different students apply prior knowledge and make new connections between prior knowledge and current problem features in different learning situations. Implications for the use of this methodology include providing insight into not only students' prior knowledge, but also how they connect this prior knowledge to problem features (i.e. dynamic knowledge transfer). It also allows the identification of instances in which external input from other students or the instructor prompted knowledge transfer to take place. The use of this dynamic knowledge transfer lens allows the addressing of gaps in student understanding, and permits further investigations of techniques that increase instances of successful knowledge transfer.
Assessment of Knowledge Transfer in the Context of Biomechanics
ERIC Educational Resources Information Center
Hutchison, Randolph E.
2011-01-01
The dynamic act of knowledge transfer, or the connection of a student's prior knowledge to features of a new problem, could be considered one of the primary goals of education. Yet studies highlight more instances of failure than success. This dissertation focuses on how knowledge transfer takes place during individual problem solving, in…
The Human Side of Knowledge Management: An Annotated Bibliography.
ERIC Educational Resources Information Center
Mayer, Pamela S.
This annotated bibliography lists books and articles that have direct application to managing the human side of knowledge acquisition, transfer, and application. What is meant by the human dimension of knowledge is how motivation and learning affect the acquisition and transfer of knowledge and how group dynamics mediate the role of knowledge in…
ERIC Educational Resources Information Center
Rinnert, Carol; Kobauashi, Hiroe; Katayama, Akemi
2015-01-01
This study takes a dynamic view of transfer as reusing and reshaping previous knowledge in new writing contexts to investigate how novice Japanese as a foreign language (JFL) writers draw on knowledge across languages to construct L1 and L2 texts. We analyzed L1 English and L2 Japanese argumentation essays by the same JFL writers (N = 19) and L1…
Developing a framework for transferring knowledge into action: a thematic analysis of the literature
Ward, Vicky; House, Allan; Hamer, Susan
2010-01-01
Objectives Although there is widespread agreement about the importance of transferring knowledge into action, we still lack high quality information about what works, in which settings and with whom. Whilst there are a large number of models and theories for knowledge transfer interventions, they are untested meaning that their applicability and relevance is largely unknown. This paper describes the development of a conceptual framework of translating knowledge into action and discusses how it can be used for developing a useful model of the knowledge transfer process. Methods A narrative review of the knowledge transfer literature identified 28 different models which explained all or part of the knowledge transfer process. The models were subjected to a thematic analysis to identify individual components and the types of processes used when transferring knowledge into action. The results were used to build a conceptual framework of the process. Results Five common components of the knowledge transfer process were identified: problem identification and communication; knowledge/research development and selection; analysis of context; knowledge transfer activities or interventions; and knowledge/research utilization. We also identified three types of knowledge transfer processes: a linear process; a cyclical process; and a dynamic multidirectional process. From these results a conceptual framework of knowledge transfer was developed. The framework illustrates the five common components of the knowledge transfer process and shows that they are connected via a complex, multidirectional set of interactions. As such the framework allows for the individual components to occur simultaneously or in any given order and to occur more than once during the knowledge transfer process. Conclusion Our framework provides a foundation for gathering evidence from case studies of knowledge transfer interventions. We propose that future empirical work is designed to test and refine the relevant importance and applicability of each of the components in order to build more useful models of knowledge transfer which can serve as a practical checklist for planning or evaluating knowledge transfer activities. PMID:19541874
False Beliefs in Unreliable Knowledge Networks
NASA Astrophysics Data System (ADS)
Ioannidis, Evangelos; Varsakelis, Nikos; Antoniou, Ioannis
2017-03-01
The aims of this work are: (1) to extend knowledge dynamics analysis in order to assess the influence of false beliefs and unreliable communication channels, (2) to investigate the impact of selection rule-policy for knowledge acquisition, (3) to investigate the impact of targeted link attacks ("breaks" or "infections") of certain "healthy" communication channels. We examine the knowledge dynamics analytically, as well as by simulations on both artificial and real organizational knowledge networks. The main findings are: (1) False beliefs have no significant influence on knowledge dynamics, while unreliable communication channels result in non-monotonic knowledge updates ("wild" knowledge fluctuations may appear) and in significant elongation of knowledge attainment. Moreover, false beliefs may emerge during knowledge evolution, due to the presence of unreliable communication channels, even if they were not present initially, (2) Changing the selection rule-policy, by raising the awareness of agents to avoid the selection of unreliable communication channels, results in monotonic knowledge upgrade and in faster knowledge attainment, (3) "Infecting" links is more harmful than "breaking" links, due to "wild" knowledge fluctuations and due to the elongation of knowledge attainment. Moreover, attacking even a "small" percentage of links (≤5%) with high knowledge transfer, may result in dramatic elongation of knowledge attainment (over 100%), as well as in delays of the onset of knowledge attainment. Hence, links of high knowledge transfer should be protected, because in Information Warfare and Disinformation, these links are the "best targets".
A Neural Network Model to Learn Multiple Tasks under Dynamic Environments
NASA Astrophysics Data System (ADS)
Tsumori, Kenji; Ozawa, Seiichi
When environments are dynamically changed for agents, the knowledge acquired in an environment might be useless in future. In such dynamic environments, agents should be able to not only acquire new knowledge but also modify old knowledge in learning. However, modifying all knowledge acquired before is not efficient because the knowledge once acquired may be useful again when similar environment reappears and some knowledge can be shared among different environments. To learn efficiently in such environments, we propose a neural network model that consists of the following modules: resource allocating network, long-term & short-term memory, and environment change detector. We evaluate the model under a class of dynamic environments where multiple function approximation tasks are sequentially given. The experimental results demonstrate that the proposed model possesses stable incremental learning, accurate environmental change detection, proper association and recall of old knowledge, and efficient knowledge transfer.
NASA Astrophysics Data System (ADS)
Hilsenbeck-Fajardo, Jacqueline L.
2009-08-01
The research described herein is a multi-dimensional attempt to measure student's abilities to recall, conceptualize, and transfer fundamental and dynamic protein structure concepts as revealed by their own diagrammatic (pictorial) representations and written self-explanations. A total of 120 participants enrolled in a 'Fundamentals of Biochemistry' course contributed to this mixed-methodological study. The population of interest consisted primarily of pre-nursing and sport and exercise science majors. This course is typically associated with a high (<30%) combined drop/failure rate, thus the course provided the researcher with an ideal context in which to apply novel transfer assessment strategies. In the past, students within this population have reported very little chemistry background. In the following study, student-generated diagrammatic representations and written explanations were coded thematically using a highly objective rubric that was designed specifically for this study. Responses provided by the students were characterized on the macroscopic, microscopic, molecular-level, and integrated scales. Recall knowledge gain (i.e., knowledge that was gained through multiple-choice questioning techniques) was quantitatively correlated to learning style preferences (i.e., high-object, low-object, and non-object). Quantitative measures revealed that participants tended toward an object (i.e., snapshot) -based visualization preference, a potentially limiting factor in their desire to consider dynamic properties of fundamental biochemical contexts such as heat-induced protein denaturation. When knowledge transfer was carefully assessed within the predefined context, numerous misconceptions pertaining to the fundamental and dynamic nature of protein structure were revealed. Misconceptions tended to increase as the transfer model shifted away from the context presented in the original learning material. Ultimately, a fundamentally new, novel, and unique measure of knowledge transfer was developed as a main result of this study. It is envisioned by the researcher that this new measure of learning is applicable specifically to physical and chemical science education-based research in the form of deep transfer on the atomic-level scale.
The Internet Knowledge Manager, Dynamic Digital Libraries, and Agents You Can Understand.
ERIC Educational Resources Information Center
Walker, Adrian
1998-01-01
Discusses the Internet Knowledge Manager (IKM) which provides an understandable way of representing knowledge, as readable software agents. Gives an example of writing and running an IKM agent for transfer pricing in corporations. Describes how the technology works. Concludes that the IKM could trigger new ways of performing knowledge management,…
Knowledge diffusion of dynamical network in terms of interaction frequency.
Liu, Jian-Guo; Zhou, Qing; Guo, Qiang; Yang, Zhen-Hua; Xie, Fei; Han, Jing-Ti
2017-09-07
In this paper, we present a knowledge diffusion (SKD) model for dynamic networks by taking into account the interaction frequency which always used to measure the social closeness. A set of agents, which are initially interconnected to form a random network, either exchange knowledge with their neighbors or move toward a new location through an edge-rewiring procedure. The activity of knowledge exchange between agents is determined by a knowledge transfer rule that the target node would preferentially select one neighbor node to transfer knowledge with probability p according to their interaction frequency instead of the knowledge distance, otherwise, the target node would build a new link with its second-order neighbor preferentially or select one node in the system randomly with probability 1 - p. The simulation results show that, comparing with the Null model defined by the random selection mechanism and the traditional knowledge diffusion (TKD) model driven by knowledge distance, the knowledge would spread more fast based on SKD driven by interaction frequency. In particular, the network structure of SKD would evolve as an assortative one, which is a fundamental feature of social networks. This work would be helpful for deeply understanding the coevolution of the knowledge diffusion and network structure.
Communication Policies in Knowledge Networks
NASA Astrophysics Data System (ADS)
Ioannidis, Evangelos; Varsakelis, Nikos; Antoniou, Ioannis
2018-02-01
Faster knowledge attainment within organizations leads to improved innovation, and therefore competitive advantage. Interventions on the organizational network may be risky or costly or time-demanding. We investigate several communication policies in knowledge networks, which reduce the knowledge attainment time without interventions. We examine the resulting knowledge dynamics for real organizational networks, as well as for artificial networks. More specifically, we investigate the dependence of knowledge dynamics on: (1) the Selection Rule of agents for knowledge acquisition, and (2) the Order of implementation of "Selection" and "Filtering". Significant decrease of the knowledge attainment time (up to -74%) can be achieved by: (1) selecting agents of both high knowledge level and high knowledge transfer efficiency, and (2) implementing "Selection" after "Filtering" in contrast to the converse, implicitly assumed, conventional prioritization. The Non-Commutativity of "Selection" and "Filtering", reveals a Non-Boolean Logic of the Network Operations. The results demonstrate that significant improvement of knowledge dynamics can be achieved by implementing "fruitful" communication policies, by raising the awareness of agents, without any intervention on the network structure.
The study on knowledge transferring incentive for information system requirement development
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Yang
2015-03-10
Information system requirement development is a process of users’ knowledge sharing and transferring. However the tacit requirements developing is a main problem during requirement development process, for the reason of difficult to encoding, express, and communicate. Knowledge fusion and corporate effort is needed to finding tacit requirements. Under this background, our paper try to find out the rule of effort dynamic evolutionary of software developer and user by building an evolutionary game model on the condition of incentive system. And in addition this paper provides an in depth discussion at the end of this paper.
Context transfer in reinforcement learning using action-value functions.
Mousavi, Amin; Nadjar Araabi, Babak; Nili Ahmadabadi, Majid
2014-01-01
This paper discusses the notion of context transfer in reinforcement learning tasks. Context transfer, as defined in this paper, implies knowledge transfer between source and target tasks that share the same environment dynamics and reward function but have different states or action spaces. In other words, the agents learn the same task while using different sensors and actuators. This requires the existence of an underlying common Markov decision process (MDP) to which all the agents' MDPs can be mapped. This is formulated in terms of the notion of MDP homomorphism. The learning framework is Q-learning. To transfer the knowledge between these tasks, the feature space is used as a translator and is expressed as a partial mapping between the state-action spaces of different tasks. The Q-values learned during the learning process of the source tasks are mapped to the sets of Q-values for the target task. These transferred Q-values are merged together and used to initialize the learning process of the target task. An interval-based approach is used to represent and merge the knowledge of the source tasks. Empirical results show that the transferred initialization can be beneficial to the learning process of the target task.
Context Transfer in Reinforcement Learning Using Action-Value Functions
Mousavi, Amin; Nadjar Araabi, Babak; Nili Ahmadabadi, Majid
2014-01-01
This paper discusses the notion of context transfer in reinforcement learning tasks. Context transfer, as defined in this paper, implies knowledge transfer between source and target tasks that share the same environment dynamics and reward function but have different states or action spaces. In other words, the agents learn the same task while using different sensors and actuators. This requires the existence of an underlying common Markov decision process (MDP) to which all the agents' MDPs can be mapped. This is formulated in terms of the notion of MDP homomorphism. The learning framework is Q-learning. To transfer the knowledge between these tasks, the feature space is used as a translator and is expressed as a partial mapping between the state-action spaces of different tasks. The Q-values learned during the learning process of the source tasks are mapped to the sets of Q-values for the target task. These transferred Q-values are merged together and used to initialize the learning process of the target task. An interval-based approach is used to represent and merge the knowledge of the source tasks. Empirical results show that the transferred initialization can be beneficial to the learning process of the target task. PMID:25610457
ERIC Educational Resources Information Center
Prawat, Richard S.
This review presents a framework that accommodates static and dynamic approaches to comprehension of students' transfer of knowledge and skill. The review focuses on three sets of variables considered fundamental to students' ability to access intellectual resources in potentially relevant situations: knowledge bases, strategies, and dispositions.…
A Model of Practice in Special Education: Dynamic Ecological Analysis
ERIC Educational Resources Information Center
Hannant, Barbara; Lim, Eng Leong; McAllum, Ruth
2010-01-01
Dynamic Ecological Analysis (DEA) is a model of practice which increases a teams' efficacy by enabling the development of more effective interventions through collaboration and collective reflection. This process has proved to be useful in: a) clarifying thinking and problem-solving, b) transferring knowledge and thinking to significant parties,…
The Role of Strategy Knowledge for the Application of Strategies in Complex Problem Solving Tasks
ERIC Educational Resources Information Center
Wüstenberg, Sascha; Stadler, Matthias; Hautamäki, Jarkko; Greiff, Samuel
2014-01-01
Education in the twenty-first century must prepare students to meet the challenges of a dynamic and interconnected world. However, assessment of students' skills tends to focus primarily on static tasks. Therefore, it is not known whether knowledge about successful strategies displayed on static tasks can be transferred to interactive and dynamic…
NASA Astrophysics Data System (ADS)
Stark, Martin; Guckenberger, Reinhard; Stemmer, Andreas; Stark, Robert W.
2005-12-01
Dynamic atomic force microscopy (AFM) offers many opportunities for the characterization and manipulation of matter on the nanometer scale with a high temporal resolution. The analysis of time-dependent forces is basic for a deeper understanding of phenomena such as friction, plastic deformation, and surface wetting. However, the dynamic characteristics of the force sensor used for such investigations are determined by various factors such as material and geometry of the cantilever, detection alignment, and the transfer characteristics of the detector. Thus, for a quantitative investigation of surface properties by dynamic AFM an appropriate system identification procedure is required, characterizing the force sensor beyond the usual parameters spring constant, quality factor, and detection sensitivity. Measurement of the transfer function provides such a characterization that fully accounts for the dynamic properties of the force sensor. Here, we demonstrate the estimation of the transfer function in a bandwidth of 1MHz from experimental data. To this end, we analyze the signal of the vibrations induced by snap-to-contact and snap-off-contact events. For the free cantilever, we determine both a parameter-free estimate [empirical transfer function estimate (ETFE)] and a parametric estimate of the transfer function. For the surface-coupled cantilever the ETFE is obtained. These identification procedures provide an intrinsic calibration as they dispense largely with a priori knowledge about the force sensor.
Pauen, Sabina; Bechtel-Kuehne, Sabrina
2016-07-01
This report investigates tool learning and its relations to executive functions (EFs) in toddlers. In Study 1 (N = 93), 18-, 20-, 22-, and 24-month-old children learned equally well to choose a correct tool from observation, whereas performance based on feedback improved with age. Knowledge transfer showed significant progress after 22 months of age: Older children ignored irrelevant features more easily and adjusted their behavior more flexibly. Study 2 (N = 62) revealed that spontaneous transfer in 22- to 24-month-olds was related to set-shifting skills and response inhibition. Flexible adaptation to feedback correlated with working-memory capacity. These findings suggest that toddlerhood is a highly dynamic phase of tool learning and that EFs are related to transfer performance at this age. © 2016 The Authors. Child Development © 2016 Society for Research in Child Development, Inc.
Investigating molecule-semiconductor interfaces with nonlinear spectroscopies
NASA Astrophysics Data System (ADS)
Giokas, Paul George
Knowledge of electronic structures and transport mechanisms at molecule-semiconductor interfaces is motivated by their ubiquity in photoelectrochemical cells. In this dissertation, optical spectroscopies are used uncover the influence of electronic coupling, coherent vibrational motion, and molecular geometry, and other factors on dynamics initiated by light absorption at such interfaces. These are explored for a family of ruthenium bipyridyl chromophores bound to titanium dioxide. Transient absorption measurements show molecular singlet state electron injection in 100 fs or less. Resonance Raman intensity analysis suggests the electronic excitations possess very little charge transfer character. The connections drawn in this work between molecular structure and photophysical behavior contribute to the general understanding of photoelectrochemical cells. Knowledge of binding geometry in nanocrystalline films is challenged by heterogeneity of semiconductor surfaces. Polarized resonance Raman spectroscopy is used to characterize the ruthenium chromophore family on single crystal titanium dioxide . Chromophores display a broad distribution of molecular geometries at the interface, with increased variation in binding angle due to the presence of a methylene bridge, as well as additional phosphonate anchors. This result implies multiple binding configurations for chromophores which incorporate multiple phosphonate ligands, and indicates the need for careful consideration when developing surface-assembled chromophore-catalyst cells. Electron transfer transitions occurring on the 100 fs time scale challenge conventional second-order approximations made when modeling these reactions. A fourth-order perturbative model which includes the relationship between coincident electron transfer and nuclear relaxation processes is presented. Insights provided by the model are illustrated for a two-level donor molecule. The presented fourth-order rate formula constitutes a rigorous and intuitive framework for understanding sub-picosecond photoinduced electron transfer dynamics. Charge transfer systems fit by this model include catechol-sensitized titanium dioxide nanoparticles and a closely-related molecular complex. These systems exhibit vibrational coherence coincident with back-electron transfer in the first picosecond after excitation, which suggests that intramolecular nuclear motion strongly influences the electronic transfer process and plays an important role in the dynamics of interfacial systems following light absorption.
Understanding knowledge transfer in an ergonomics intervention at a poultry processing plant.
Antle, David M; MacKinnon, Scott N; Molgaard, John; Vézina, Nicole; Parent, Robert; Bornstein, Stephen; Leclerc, Louise
2011-01-01
This case study reviews the knowledge transfer (KT) process of implementing a knife sharpening and steeling program into a poultry processing plant via a participatory ergonomics intervention. This ergonomics intervention required stakeholder participation at the company level to move a 'train-the-trainer' program, developed in Québec, Canada, into action on the plant's deboning line. Communications and exchanges with key stakeholders, as well as changes in steeling and production behaviours were recorded. The intervention was assumed to be at least partially successful because positive changes in work operations occurred. Ergonomic-related changes such as those documented have been cited in the academic literature as beneficial to worker health. However, several components cited in literature that are associated with a successful participatory ergonomics intervention were not attained during the project. A Dynamic Knowledge Transfer Model was used to identify KT issues that impacted on the success of train-the-trainer program. A debriefing analysis reveals that a failure to consider key participatory ergonomics factors necessary for success were related to capacity deficits in the knowledge dissemination strategy.
Montalto, Alessandro; Faes, Luca; Marinazzo, Daniele
2014-01-01
A challenge for physiologists and neuroscientists is to map information transfer between components of the systems that they study at different scales, in order to derive important knowledge on structure and function from the analysis of the recorded dynamics. The components of physiological networks often interact in a nonlinear way and through mechanisms which are in general not completely known. It is then safer that the method of choice for analyzing these interactions does not rely on any model or assumption on the nature of the data and their interactions. Transfer entropy has emerged as a powerful tool to quantify directed dynamical interactions. In this paper we compare different approaches to evaluate transfer entropy, some of them already proposed, some novel, and present their implementation in a freeware MATLAB toolbox. Applications to simulated and real data are presented.
Montalto, Alessandro; Faes, Luca; Marinazzo, Daniele
2014-01-01
A challenge for physiologists and neuroscientists is to map information transfer between components of the systems that they study at different scales, in order to derive important knowledge on structure and function from the analysis of the recorded dynamics. The components of physiological networks often interact in a nonlinear way and through mechanisms which are in general not completely known. It is then safer that the method of choice for analyzing these interactions does not rely on any model or assumption on the nature of the data and their interactions. Transfer entropy has emerged as a powerful tool to quantify directed dynamical interactions. In this paper we compare different approaches to evaluate transfer entropy, some of them already proposed, some novel, and present their implementation in a freeware MATLAB toolbox. Applications to simulated and real data are presented. PMID:25314003
NASA Astrophysics Data System (ADS)
Cheng, Po-Hsun; Chen, Sao-Jie; Lai, Jin-Shin; Lai, Feipei
This paper illustrates a feasible health informatics domain knowledge management process which helps gather useful technology information and reduce many knowledge misunderstandings among engineers who have participated in the IBM mainframe rightsizing project at National Taiwan University (NTU) Hospital. We design an asynchronously sharing mechanism to facilitate the knowledge transfer and our health informatics domain knowledge management process can be used to publish and retrieve documents dynamically. It effectively creates an acceptable discussion environment and even lessens the traditional meeting burden among development engineers. An overall description on the current software development status is presented. Then, the knowledge management implementation of health information systems is proposed.
Schryer, David W.; Peterson, Pearu; Illaste, Ardo; Vendelin, Marko
2012-01-01
To characterize intracellular energy transfer in the heart, two organ-level methods have frequently been employed: inversion and saturation transfer, and dynamic labeling. Creatine kinase (CK) fluxes obtained by following oxygen labeling have been considerably smaller than the fluxes determined by saturation transfer. It has been proposed that dynamic labeling determines net flux through CK shuttle, whereas saturation transfer measures total unidirectional flux. However, to our knowledge, no sensitivity analysis of flux determination by oxygen labeling has been performed, limiting our ability to compare flux distributions predicted by different methods. Here we analyze oxygen labeling in a physiological heart phosphotransfer network with active CK and adenylate kinase (AdK) shuttles and establish which fluxes determine the labeling state. A mathematical model consisting of a system of ordinary differential equations was composed describing enrichment in each phosphoryl group and inorganic phosphate. By varying flux distributions in the model and calculating the labeling, we analyzed labeling sensitivity to different fluxes in the heart. We observed that the labeling state is predominantly sensitive to total unidirectional CK and AdK fluxes and not to net fluxes. We conclude that measuring dynamic incorporation of into the high-energy phosphotransfer network in heart does not permit unambiguous determination of energetic fluxes with a higher magnitude than the ATP synthase rate when the bidirectionality of fluxes is taken into account. Our analysis suggests that the flux distributions obtained using dynamic labeling, after removing the net flux assumption, are comparable with those from inversion and saturation transfer. PMID:23236266
Distance learning education for mitigation/adaptation policy: a case study
NASA Astrophysics Data System (ADS)
Slini, T.; Giama, E.; Papadopoulou, Ch.-O.
2016-02-01
The efficient training of young environmental scientists has proven to be a challenging goal over the last years, while several dynamic initiatives have been developed aiming to provide complete and consistent education. A successful example is the e-learning course for participants mainly coming from emerging economy countries 'Development of mitigation/adaptation policy portfolios' organised in the frame of the project Promitheas4: Knowledge transfer and research needs for preparing mitigation/adaptation policy portfolios, aiming to provide knowledge transfer, enhance new skills and competencies, using modern didactic approaches and learning technologies. The present paper addresses the experience and the results of these actions, which seem promising and encouraging and were broadly welcomed by the participants.
Robust sensorimotor representation to physical interaction changes in humanoid motion learning.
Shimizu, Toshihiko; Saegusa, Ryo; Ikemoto, Shuhei; Ishiguro, Hiroshi; Metta, Giorgio
2015-05-01
This paper proposes a learning from demonstration system based on a motion feature, called phase transfer sequence. The system aims to synthesize the knowledge on humanoid whole body motions learned during teacher-supported interactions, and apply this knowledge during different physical interactions between a robot and its surroundings. The phase transfer sequence represents the temporal order of the changing points in multiple time sequences. It encodes the dynamical aspects of the sequences so as to absorb the gaps in timing and amplitude derived from interaction changes. The phase transfer sequence was evaluated in reinforcement learning of sitting-up and walking motions conducted by a real humanoid robot and compatible simulator. In both tasks, the robotic motions were less dependent on physical interactions when learned by the proposed feature than by conventional similarity measurements. Phase transfer sequence also enhanced the convergence speed of motion learning. Our proposed feature is original primarily because it absorbs the gaps caused by changes of the originally acquired physical interactions, thereby enhancing the learning speed in subsequent interactions.
Digging into construction: social networks and their potential impact on knowledge transfer.
Carlan, N A; Kramer, D M; Bigelow, P; Wells, R; Garritano, E; Vi, P
2012-01-01
A six-year study is exploring the most effective ways to disseminate ideas to reduce musculoskeletal disorders (MSDs) in the construction sector. The sector was targeted because MSDs account for 35% of all lost time injuries. This paper reports on the organization of the construction sector, and maps potential pathways of communication, including social networks, to set the stage for future dissemination. The managers, health and safety specialists, union health and safety representatives, and 28 workers from small, medium and large construction companies participated. Over a three-year period, data were collected from 47 qualitative interviews. Questions were guided by the PARIHS (Promoting Action on Research Implementation in Health Services) knowledge-transfer conceptual framework and adapted for the construction sector. The construction sector is a complex and dynamic sector, with non-linear reporting relationships, and divided and diluted responsibilities. Four networks were identified that can potentially facilitate the dissemination of new knowledge: worksite-project networks; union networks; apprenticeship program networks; and networks established by the Construction Safety Association/Infrastructure Health and Safety Association. Flexible and multi-directional lines of communication must be used in this complex environment. This has implications for the future choice of knowledge transfer strategies.
Stochastic abstract policies: generalizing knowledge to improve reinforcement learning.
Koga, Marcelo L; Freire, Valdinei; Costa, Anna H R
2015-01-01
Reinforcement learning (RL) enables an agent to learn behavior by acquiring experience through trial-and-error interactions with a dynamic environment. However, knowledge is usually built from scratch and learning to behave may take a long time. Here, we improve the learning performance by leveraging prior knowledge; that is, the learner shows proper behavior from the beginning of a target task, using the knowledge from a set of known, previously solved, source tasks. In this paper, we argue that building stochastic abstract policies that generalize over past experiences is an effective way to provide such improvement and this generalization outperforms the current practice of using a library of policies. We achieve that contributing with a new algorithm, AbsProb-PI-multiple and a framework for transferring knowledge represented as a stochastic abstract policy in new RL tasks. Stochastic abstract policies offer an effective way to encode knowledge because the abstraction they provide not only generalizes solutions but also facilitates extracting the similarities among tasks. We perform experiments in a robotic navigation environment and analyze the agent's behavior throughout the learning process and also assess the transfer ratio for different amounts of source tasks. We compare our method with the transfer of a library of policies, and experiments show that the use of a generalized policy produces better results by more effectively guiding the agent when learning a target task.
Patrick, Walter K
2011-09-01
Developmental strategies over the last 4 decades have generally tended to transfer knowledge and technology along north-south axes as trickle-down theories in development, especially in health knowledge transfers, prevailed. Limited efforts in development assistance for health (DAH) were made to promote south-south cooperation for basic health needs. Globalization with increased educational networks and development health assistance has enhanced the potential for more effective south-south partnerships for health. The stages of development in a consortium and key catalysts in the metamorphosis to a south-south partnership are identified: leadership, resources, expertise, visibility participation, and dynamism of a critical mass of young professionals. Copyright © 2011 Elsevier Inc. All rights reserved.
Energy transfer in Tm,Ho:KYW crystal and diode-pumped microchip laser operation.
Kurilchik, Sergey; Gusakova, Natali; Demesh, Maxim; Yasukevich, Anatol; Kisel, Viktor; Pavlyuk, Anatoly; Kuleshov, Nikolai
2016-03-21
An investigation of Tm-Ho energy transfer in Tm(5at.%),Ho(0.4at.%):KYW single crystal by two independent techiques was performed. Based on fluorescence dynamics measurements, energy transfer parameters P71 and P28 for direct (Tm→Ho) and back (Ho→Tm) transfers, respectively, as well as equilibrium constant Θ were evaluated. The obtained results were supported by calculation of microscopic interaction parameters according to the Förster-Dexter theory for a dipole-dipole interaction. Diode-pumped continuous-wave operation of Tm,Ho:KYW microchip laser was demonstrated, for the first time to our knowledge. Maximum output power of 77 mW at 2070 nm was achieved at the fundamental TEM00 mode.
Pamboukian, Marilena Martins; Pereira, Carlos Augusto; Augusto, Elisabeth de Fatima Pires; Tonso, Aldo
2011-12-01
Monitoring the specific respiration rate (Q(O2)) is a valuable tool to evaluate cell growth and physiology. However, for low Q(O2) values the accuracy may depend on the measurement methodology, as it is the case in animal cell culture. The widely used "Dynamic Method" imposes serious difficulties concerning oxygen transfer cancellation, especially through membrane oxygenation. This paper presents an improved procedure to this method, through an automated control of the gas inlet composition that can minimize the residual oxygen transfer driving force during the Q(O2) measurement phase. The improved technique was applied to animal cell cultivation, particularly three recombinant S2 (Drosophila melanogaster) insect cell lines grown in a membrane aeration bioreactor. The average measurements of the proposed method reached 98% of stationary liquid phase balance method, taken as a reference, compared to 21% when the traditional method was used. Furthermore, this methodology does not require knowledge of the volumetric transfer coefficient k(L)a, which may vary during growth. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Knowledge transfer within EU-funded marine science research - a viewpoint
NASA Astrophysics Data System (ADS)
Bayliss-Brown, Georgia; Cheallachaín, Cliona Ní
2016-04-01
Knowledge transfer, in its most inherent form, can be tracked back to the earliest phase of the Neolithic Revolution, 10,000 years ago, at a time when innovators shared their thoughts on crop cultivation and livestock farming (Bellwood, 2004). Not to be mistaken for science transfer - the export of modern science to non-scientific audiences - it was in the 1960s, that modern knowledge transfer was initiated, when reporting research achievements shifted towards having institutional and political agendas (Lipphardt & Ludwig, 2011). Albeit that the economic contribution of scientific research has been scrutinised for decades; today, there is a pronounced need for the evaluation of its social, cultural and ecological impact. To have impact, it is essential that scientific knowledge is clear and accessible, as well as robust and credible, so that it can be successfully transferred and applied by those identifying solutions for today's societal and environmental challenges. This phenomenon is receiving growing academic interest, where publications including "knowledge transfer" in the title have increased near exponentially for 60 years. Furthermore, we are seeing a definite shift towards embedding a mission of knowledge transfer in Public Research Organisations. This new approach is rewarding researchers whom deliver on all three institutional missions: teaching, research and knowledge transfer. In addition, the European Commission (2008) recommends that "knowledge transfer between universities and industry is made a permanent political and operational priority" and that "sufficient resources and incentives [be] available to public research organisations and their staff to engage in knowledge transfer activities". It is also anticipated that funding agencies will soon make pathways-to-impact statements, also known as knowledge transfer plans, a mandatory requirement of all project proposals. AquaTT is a leader in scientific knowledge management, including knowledge transfer and dissemination. This Dublin-based SME has an ever-growing portfolio of FP7 and Horizon 2020 projects where they hold knowledge management responsibilities. In this session, we will present AquaTT's experiences in knowledge management for several European Union-funded marine research projects; including MarineTT (http://marinett.eu/) that was recognised as an exemplar project in the ex post evaluation of FP7 to the European Commission. These insights will be supplemented with an overview of the AquaTT-developed step-by-step knowledge transfer methodology, as used by the COLUMBUS project - the EU's flagship Blue Growth and Knowledge Transfer initiative (http://www.columbusproject.eu/). This session will provide a platform to launch AquaTT's European knowledge transfer network, established to support the research community in fostering a culture that recognises and rewards knowledge transfer between scientists and end-users (industry, policy, and wider society), thereby ensuring that research achieves its maximum potential impact. References Bellwood, P. (2004) The First Farmers: Origins of Agricultural Societies. Malden, MA. European Commission (2008) recommendation on the management of intellectual property in knowledge transfer activities and code of practice for universities and other public research organisations http://ec.europa.eu/invest-in-research/pdf/ip_recommendation_en.pdf Lipphardt, V. and D. Ludwig (2011) Knowledge transfer and science transfer. http://ieg-ego.eu/en/threads/theories-and-methods/knowledge-transfer/veronika-lipphardt-david-ludwig-knowledge-transfer-and-science-transfer
ERIC Educational Resources Information Center
Kuzle, Ana
2017-01-01
Students regularly struggle with mathematical tasks, particularly those concerning non-routine problems in geometry. Although educators would like for their learners to transfer their knowledge to non-routine and real-life situations, students run into a number of difficulties. The goal of this exploratory study was to analyze three participants'…
Heat Transfer Principles in Thermal Calculation of Structures in Fire
Zhang, Chao; Usmani, Asif
2016-01-01
Structural fire engineering (SFE) is a relatively new interdisciplinary subject, which requires a comprehensive knowledge of heat transfer, fire dynamics and structural analysis. It is predominantly the community of structural engineers who currently carry out most of the structural fire engineering research and design work. The structural engineering curriculum in universities and colleges do not usually include courses in heat transfer and fire dynamics. In some institutions of higher education, there are graduate courses for fire resistant design which focus on the design approaches in codes. As a result, structural engineers who are responsible for structural fire safety and are competent to do their jobs by following the rules specified in prescriptive codes may find it difficult to move toward performance-based fire safety design which requires a deep understanding of both fire and heat. Fire safety engineers, on the other hand, are usually focused on fire development and smoke control, and may not be familiar with the heat transfer principles used in structural fire analysis, or structural failure analysis. This paper discusses the fundamental heat transfer principles in thermal calculation of structures in fire, which might serve as an educational guide for students, engineers and researchers. Insights on problems which are commonly ignored in performance based fire safety design are also presented. PMID:26783379
NASA Astrophysics Data System (ADS)
Martin, Deloris
Purpose. The purpose of this study was to describe the existing knowledge transfer practices in selected aerospace companies as perceived by highly experienced engineers retiring from the company. Specifically it was designed to investigate and describe (a) the processes and procedures used to transfer knowledge, (b) the systems that encourage knowledge transfer, (c) the impact of management actions on knowledge transfer, and (d) constraining factors that might impede knowledge transfer. Methodology. A descriptive case study was the methodology applied in this study. Qualitative data were gathered from highly experienced engineers from 3 large aerospace companies in Southern California. A semistructured interview was conducted face-to-face with each participant in a private or semiprivate, non-workplace setting to obtain each engineer's perspectives on his or her company's current knowledge transfer practices. Findings. The participants in this study preferred to transfer knowledge using face-to-face methods, one-on-one, through actual troubleshooting and problem-solving scenarios. Managers in these aerospace companies were observed as having knowledge transfer as a low priority; they tend not to promote knowledge transfer among their employees. While mentoring is the most common knowledge transfer system these companies offer, it is not the preferred method of knowledge transfer among the highly experienced engineers. Job security and schedule pressures are the top constraints that impede knowledge transfer between the highly experienced engineers and their coworkers. Conclusions. The study data support the conclusion that the highly experienced engineers in the study's aerospace companies would more likely transfer their knowledge to those remaining in the industry if the transfer could occur face-to-face with management support and acknowledgement of their expertise and if their job security is not threatened. The study also supports the conclusion that managers should be responsible for the leadership in developing a knowledge-sharing culture and rewarding those who do share. Recommendations. It is recommended that a quantitative study of highly experienced engineers in aerospace be conducted to determine the degree to which knowledge-sharing methods, processes, and procedures may be effective in capturing their knowledge. It is also recommended that a replication of this study be undertaken to include the perspectives of first-line managers on developing a knowledge-sharing culture for the aerospace industry.
A Map-Based Service Supporting Different Types of Geographic Knowledge for the Public
Zhou, Mengjie; Wang, Rui; Tian, Jing; Ye, Ning; Mai, Shumin
2016-01-01
The internet enables the rapid and easy creation, storage, and transfer of knowledge; however, services that transfer geographic knowledge and facilitate the public understanding of geographic knowledge are still underdeveloped to date. Existing online maps (or atlases) can support limited types of geographic knowledge. In this study, we propose a framework for map-based services to represent and transfer different types of geographic knowledge to the public. A map-based service provides tools to ensure the effective transfer of geographic knowledge. We discuss the types of geographic knowledge that should be represented and transferred to the public, and we propose guidelines and a method to represent various types of knowledge through a map-based service. To facilitate the effective transfer of geographic knowledge, tools such as auxiliary background knowledge and auxiliary map-reading tools are provided through interactions with maps. An experiment conducted to illustrate our idea and to evaluate the usefulness of the map-based service is described; the results demonstrate that the map-based service is useful for transferring different types of geographic knowledge. PMID:27045314
A Map-Based Service Supporting Different Types of Geographic Knowledge for the Public.
Zhou, Mengjie; Wang, Rui; Tian, Jing; Ye, Ning; Mai, Shumin
2016-01-01
The internet enables the rapid and easy creation, storage, and transfer of knowledge; however, services that transfer geographic knowledge and facilitate the public understanding of geographic knowledge are still underdeveloped to date. Existing online maps (or atlases) can support limited types of geographic knowledge. In this study, we propose a framework for map-based services to represent and transfer different types of geographic knowledge to the public. A map-based service provides tools to ensure the effective transfer of geographic knowledge. We discuss the types of geographic knowledge that should be represented and transferred to the public, and we propose guidelines and a method to represent various types of knowledge through a map-based service. To facilitate the effective transfer of geographic knowledge, tools such as auxiliary background knowledge and auxiliary map-reading tools are provided through interactions with maps. An experiment conducted to illustrate our idea and to evaluate the usefulness of the map-based service is described; the results demonstrate that the map-based service is useful for transferring different types of geographic knowledge.
I Learned More than I Taught: The Hidden Dimension of Learning in Intercultural Knowledge Transfer
ERIC Educational Resources Information Center
Chen, Fang; Bapuji, Hari; Dyck, Bruno; Wang, Xiaoyun
2012-01-01
Purpose: Although knowledge transfer is generally conceived as a two-way process in which knowledge is transferred to and from the knowledge source, research has tended to focus on the first part of the process and neglect the second part. This study aims to examine the feedback loop and how knowledge is transferred from the knowledge receiver to…
A critical narrative review of transfer of basic science knowledge in health professions education.
Castillo, Jean-Marie; Park, Yoon Soo; Harris, Ilene; Cheung, Jeffrey J H; Sood, Lonika; Clark, Maureen D; Kulasegaram, Kulamakan; Brydges, Ryan; Norman, Geoffrey; Woods, Nicole
2018-06-01
'Transfer' is the application of a previously learned concept to solve a new problem in another context. Transfer is essential for basic science education because, to be valuable, basic science knowledge must be transferred to clinical problem solving. Therefore, better understanding of interventions that enhance the transfer of basic science knowledge to clinical reasoning is essential. This review systematically identifies interventions described in the health professions education (HPE) literature that document the transfer of basic science knowledge to clinical reasoning, and considers teaching and assessment strategies. A systematic search of the literature was conducted. Articles related to basic science teaching at the undergraduate level in HPE were analysed using a 'transfer out'/'transfer in' conceptual framework. 'Transfer out' refers to the application of knowledge developed in one learning situation to the solving of a new problem. 'Transfer in' refers to the use of previously acquired knowledge to learn from new problems or learning situations. Of 9803 articles initially identified, 627 studies were retrieved for full text evaluation; 15 were included in the literature review. A total of 93% explored 'transfer out' to clinical reasoning and 7% (one article) explored 'transfer in'. Measures of 'transfer out' fostered by basic science knowledge included diagnostic accuracy over time and in new clinical cases. Basic science knowledge supported learning - 'transfer in' - of new related content and ultimately the 'transfer out' to diagnostic reasoning. Successful teaching strategies included the making of connections between basic and clinical sciences, the use of commonsense analogies, and the study of multiple clinical problems in multiple contexts. Performance on recall tests did not reflect the transfer of basic science knowledge to clinical reasoning. Transfer of basic science knowledge to clinical reasoning is an essential component of HPE that requires further development for implementation and scholarship. © 2018 John Wiley & Sons Ltd and The Association for the Study of Medical Education.
Multi-step optimization strategy for fuel-optimal orbital transfer of low-thrust spacecraft
NASA Astrophysics Data System (ADS)
Rasotto, M.; Armellin, R.; Di Lizia, P.
2016-03-01
An effective method for the design of fuel-optimal transfers in two- and three-body dynamics is presented. The optimal control problem is formulated using calculus of variation and primer vector theory. This leads to a multi-point boundary value problem (MPBVP), characterized by complex inner constraints and a discontinuous thrust profile. The first issue is addressed by embedding the MPBVP in a parametric optimization problem, thus allowing a simplification of the set of transversality constraints. The second problem is solved by representing the discontinuous control function by a smooth function depending on a continuation parameter. The resulting trajectory optimization method can deal with different intermediate conditions, and no a priori knowledge of the control structure is required. Test cases in both the two- and three-body dynamics show the capability of the method in solving complex trajectory design problems.
Research Reports: 1988 NASA/ASEE Summer Faculty Fellowship Program
NASA Technical Reports Server (NTRS)
Freeman, L. Michael (Editor); Chappell, Charles R. (Editor); Cothran, Ernestine K. (Editor); Karr, Gerald R. (Editor)
1988-01-01
The basic objectives are to further the professional knowledge of qualified engineering and science faculty members; to stimulate an exchange of ideas between participants and NASA: to enrich and refresh the research and teaching activities of the participants' institutions; and to contribute to the research objectives of the NASA centers. Topics addressed include: cryogenics; thunderstorm simulation; computer techniques; computer assisted instruction; system analysis weather forecasting; rocket engine design; crystal growth; control systems design; turbine pumps for the Space Shuttle Main engine; electron mobility; heat transfer predictions; rotor dynamics; mathematical models; computational fluid dynamics; and structural analysis.
Global Knowledge Transfer Issues. Symposium 12. [AHRD Conference, 2001].
ERIC Educational Resources Information Center
2001
This document contains three papers on global knowledge transfer issues and human resource development (HRD). "Indigenizing Knowledge Transfer" (Gary N. McLean) explores examples of HRD in which ethnocentric perspectives predominate and argues that, unless a HRD develops a global perspective, efforts to transfer knowledge within academia…
Newell, Sue; Edelman, Linda; Scarbrough, Harry; Swan, Jacky; Bresnen, Mike
2003-02-01
A core prescription from the knowledge management movement is that the successful management of organizational knowledge will prevent firms from 'reinventing the wheel', in particular through the transfer of 'best practices'. Our findings challenge this logic. They suggest instead that knowledge is emergent and enacted in practice, and that normally those involved in a given practice have only a partial understanding of the overall practice. Generating knowledge about current practice is therefore a precursor to changing that practice. In this sense, knowledge transfer does not occur independently of or in sequence to knowledge generation, but instead the process of knowledge generation and its transfer are inexorably intertwined. Thus, rather than transferring 'product' knowledge about the new 'best practice' per se, our analysis suggests that it is more useful to transfer 'process' knowledge about effective ways to generate the knowledge of existing practice, which is the essential starting point for attempts to change that practice.
On knowledge transfer management as a learning process for ad hoc teams
NASA Astrophysics Data System (ADS)
Iliescu, D.
2017-08-01
Knowledge management represents an emerging domain becoming more and more important. Concepts like knowledge codification and personalisation, knowledge life-cycle, social and technological dimensions, knowledge transfer and learning management are integral parts. Focus goes here in the process of knowledge transfer for the case of ad hoc teams. The social dimension of knowledge transfer plays an important role. No single individual actors involved in the process, but a collective one, representing the organisation. It is critically important for knowledge to be managed from the life-cycle point of view. A complex communication network needs to be in place to supports the process of knowledge transfer. Two particular concepts, the bridge tie and transactive memory, would eventually enhance the communication. The paper focuses on an informational communication platform supporting the collaborative work on knowledge transfer. The platform facilitates the creation of a topic language to be used in knowledge modelling, storage and reuse, by the ad hoc teams.
The Institutional Organisation of Knowledge Transfer and Its Implications
ERIC Educational Resources Information Center
van der Heide, Sjors; van der Sijde, Peter C.; Terlouw, Cees
2008-01-01
How do European universities organise the knowledge transfer (KT) task? We consider the institutional organisation of knowledge transfer as encompassing 1) the knowledge transfer office structure, i.e. the way universities have embedded and organise their KT activities, 2) the focus towards the KT task, linked to the KT strategy, and 3) the KT…
The role of satellite altimetry in climate studies
NASA Technical Reports Server (NTRS)
Parsons, C. L.
1980-01-01
The results of three generations of satellite-borne radar altimetry experiments are summarized. The diverse measurements possible from this instrument are shown to be directly applicable to studies of the importance of the oceans in climate. The radar altimeter has unique value for investigations seeking knowledge of the interconnections between ocean dynamics, heat and momentum transfer across the air-sea interface, sea ice extent, and polar ice sheet thickness.
DOE Office of Scientific and Technical Information (OSTI.GOV)
AL-Dahhan, Muthanna; Rizwan-Uddin, Rizwan; Usman, S.
All the goals and the objectives set for the project were successfully executed and achieved and all the milestones have been successfully completed. The results that have been obtained for the first time advance the scientific and engineering knowledge and understanding of the plenum-to plenum natural convection of prismatic block nuclear reactors that is encountered during accident or abnormal operation. These have been accomplished by developing and implementing for the first time unique and flexible scaled-down separate and integrated effects experimental plenumto- plenum facility (P2PF) with dual channels at this time that has been equipped with sophisticated measurement techniques integratedmore » in a novel way on the heated and cooled channels. The unique facility is an asset now that can be extended to research multiple channels and to study the effects of hot plumes in the plena for future projects if funding will be available. It can also be modified to research natural convection of pebble bed reactors. Hence, it complement the HTTF at Oregon State University. However, in this study, heat transfer coefficients from the inner wall surface to the flowing gas (both helium and air were used) and the radial temperature and gas velocity profiles have been measured and investigated along the height of the heated and cooled channels using in house developed wall flush mounted heat transfer probes, thermocouple with in house developed adjuster for radial movement with 1 mm increment inside the channel and hot wire anemometry with also in house developed adjuster for 1 mm radial movement inside the channel, respectively. Also advanced tracer technique has been developed to quantify also for the first time the dispersion of the gas dynamics of the hot and cold channels. The research has provided new knowledge and new benchmarking data that can be used to validate computational fluid dynamics (CFD) codes with conjugate heat transfer. The work and its results that have been performed within the budget have demonstrated their superior technical effectiveness and high economic feasibility to perform needed studies for safety analysis and assessment at least cost for these types of gas cooled very high temperature 4th generation nuclear reactors. Accordingly, the results obtained in this project and the unique facility and techniques that have been developed will benefit greatly the public by advancing the technology of the prismatic block nuclear reactors toward commercialization and to ensure they will be designed and operated safely by utilizing the obtained knowledge and having well validated CFD simulations integrated with heat transfer computations« less
Tara K. McGee; Allan Curtis; Bonita L. McFarlane; Bruce Shindler; Amy Christianson; Christine Olsen; Sarah M. McCaffrey
2016-01-01
The importance of knowledge transfer between researchers, policy makers and practitioners is widely recognized. However, barriers to knowledge transfer can make it difficult for practitioners to apply the results of scientific research. This paper describes a project that addressed barriers to knowledge transfer by involving wildfire management practitioners from three...
Understanding of anesthesia machine function is enhanced with a transparent reality simulation.
Fischler, Ira S; Kaschub, Cynthia E; Lizdas, David E; Lampotang, Samsun
2008-01-01
Photorealistic simulations may provide efficient transfer of certain skills to the real system, but by being opaque may fail to encourage deeper learning of the structure and function of the system. Schematic simulations that are more abstract, with less visual fidelity but make system structure and function transparent, may enhance deeper learning and optimize retention and transfer of learning. We compared learning effectiveness of these 2 modes of externalizing the output of a common simulation engine (the Virtual Anesthesia Machine, VAM) that models machine function and dynamics and responds in real time to user interventions such as changes in gas flow or ventilation. Undergraduate students (n = 39) and medical students (n = 35) were given a single, 1-hour guided learning session with either a Transparent or an Opaque version of the VAM simulation. The following day, the learners' knowledge of machine components, function, and dynamics was tested. The Transparent-VAM groups scored higher than the Opaque-VAM groups on a set of multiple-choice questions concerning conceptual knowledge about anesthesia machines (P = 0.009), provided better and more complete explanations of component function (P = 0.003), and were more accurate in remembering and inferring cause-and-effect dynamics of the machine and relations among components (P = 0.003). Although the medical students outperformed undergraduates on all measures, a similar pattern of benefits for the Transparent VAM was observed for these 2 groups. Schematic simulations that transparently allow learners to visualize, and explore, underlying system dynamics and relations among components may provide a more effective mental model for certain systems. This may lead to a deeper understanding of how the system works, and therefore, we believe, how to detect and respond to potentially adverse situations.
Supported Workplace Learning: A Knowledge Transfer Paradigm
ERIC Educational Resources Information Center
Burns, George R.; Paton, Robert R.
2005-01-01
The importance of knowledge to the effective development of economic growth in the twenty-first century has led to a number of initiatives such as lifelong learning, skills development and knowledge transfer. Of these, knowledge transfer has predominantly been concerned with the commercial exploitation of research knowledge. This article suggests…
ERIC Educational Resources Information Center
Sankowska, Anna
2013-01-01
Purpose: This study seeks to provide empirical evidence of relationships between organizational trust, knowledge transfer, creation and innovativeness at the firm level. It aims to hypothesize a mediational model implying that organizational trust is related to knowledge transfer, which will, in turn, enhance knowledge creation, thereby…
Momentum Transfer in a Spinning Fuel Tank Filled with Xenon
NASA Technical Reports Server (NTRS)
Peugeot, John W.; Dorney, Daniel J.
2006-01-01
Transient spin-up and spin-down flows inside of spacecraft fuel tanks need to be analyzed in order to properly design spacecraft control systems. Knowledge of the characteristics of angular momentum transfer to and from the fuel is used to size the de-spin mechanism that places the spacecraft in a controllable in-orbit state. In previous studies, several analytical models of the spin-up process were developed. However, none have accurately predicted all of the flow dynamics. Several studies have also been conducted using Navier-Stokes based methods. These approaches have been much more successful at simulating the dynamic processes in a cylindrical container, but have not addressed the issue of momentum transfer. In the current study, the spin-up and spin-down of a fuel tank filled with gaseous xenon has been investigated using a three-dimensional unsteady Navier-Stokes code. Primary interests have been concentrated on the spin-up/spin-down time constants and the initial torque imparted on the system. Additional focus was given to the relationship between the dominant flow dynamics and the trends in momentum transfer. Through the simulation of both a cylindrical and a spherical tank, it was revealed that the transfer of angular momentum is nonlinear at early times and tends toward a linear pattern at later times. Further investigation suggests that the nonlinear spin up is controlled by the turbulent transport of momentum, while the linear phase is controlled by a Coriolis driven (Ekman) flow along the outer wall. These results indicate that the spinup and spin-down processes occur more quickly in tanks with curved surfaces than those with defined top, bottom, and side walls. The results also provide insights for the design of spacecraft de-spin mechanisms.
Grave, Daniel A; Yatom, Natav; Ellis, David S; Toroker, Maytal Caspary; Rothschild, Avner
2018-03-05
In recent years, hematite's potential as a photoanode material for solar hydrogen production has ignited a renewed interest in its physical and interfacial properties, which continues to be an active field of research. Research on hematite photoanodes provides new insights on the correlations between electronic structure, transport properties, excited state dynamics, and charge transfer phenomena, and expands our knowledge on solar cell materials into correlated electron systems. This research news article presents a snapshot of selected theoretical and experimental developments linking the electronic structure to the photoelectrochemical performance, with particular focus on optoelectronic properties and charge carrier dynamics. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Evaluating knowledge transfer practices among construction organization in Malaysia
NASA Astrophysics Data System (ADS)
Zaidi, Mohd Azian; Baharuddin, Mohd Nurfaisal; Bahardin, Nur Fadhilah; Yasin, Mohd Fadzil Mat; Nawi, Mohd Nasrun Mohd; Deraman, Rafikullah
2016-08-01
The aims of this paper is to identify a key dimension of knowledge transfer component to improve construction organization performance. It investigates the effectiveness of present knowledge transfer practices currently adopted by the Malaysian construction organizations and examines the relationship between knowledge transfer factors and organizational factors. A survey among 151 respondents including a different contractor registration grade was employed for the study. The survey shows that a seven-teen (17) factors known as creating shared awareness for information sharing, communication, personal skills,individual attitude,training, organizational culture, information technology,motivation, monitoring and supervision, service quality,information accessibility, information supply, socialization process,knowledge tools, coaching and monitoring, staff briefing and information sharing were identify as a key dimension for knowledge transfer success. This finding suggest that through improvement of each factor, the recognition of the whole strategic knowledge transfer process can be increase thus helping to strengthen the Malaysian construction organization for competitive advantages.
Getting the message across: principles for developing brief-Knowledge Transfer (b-KT) communiqués.
Shaw, Lynn
2012-01-01
This feature article on knowledge transfer presents principles and strategies to support the development of short communiqués to end-users. Formal and informal knowledge brokers are the targeted users of the strategies. Research studies and conceptual literature in knowledge transfer informed the development of brief-Knowledge Transfer (b-KT) principles. Principles are explained and a sample of how they informed the development of KIT-Tip Sheets is offered to promote ways to use principles in knowledge dissemination. b-KT principles can be used as a framework to guide the development of short communiqués by knowledge brokers in work practice but also in the health, social and rehabilitation domains. In addition, these principles promote the participation of end-users in the development of knowledge transfer. Formal evaluation is needed on the use of these principles in achieving the uptake and use of knowledge by end-users.
Femtosecond dynamics of a cardiotonic medicine (milrinone) in neutral water
NASA Astrophysics Data System (ADS)
Gil, M.; Douhal, A.
2006-09-01
Milrinone is a medicine used to attenuate heart attack disease. Understanding its interaction with water is of importance for the knowledge of its stability and related phenomena. This intimate information requires the unraveling of the dynamics under the physiological conditions. Here we report the first study of ultrafast processes of this medicine. We show that S 2 relaxation of the keto structure (K) occurs in ˜150 fs and the intramolecular-charge transfer reaction in less than 100 fs to produce a relaxed CT-K state. An observed ˜10 ps decay is assigned to vibrational relaxation/cooling and twisting in the formed CT-K.
ERIC Educational Resources Information Center
Anthony, Seth
2014-01-01
Part I: Students' participation in inquiry-based chemistry laboratory curricula, and, in particular, engagement with key thinking processes in conjunction with these experiences, is linked with success at the difficult task of "transfer"--applying their knowledge in new contexts to solve unfamiliar types of problems. We investigate…
NASA Astrophysics Data System (ADS)
Esposti Ongaro, T.; Barsotti, S.; de'Michieli Vitturi, M.; Favalli, M.; Longo, A.; Nannipieri, L.; Neri, A.; Papale, P.; Saccorotti, G.
2009-12-01
Physical and numerical modelling is becoming of increasing importance in volcanology and volcanic hazard assessment. However, new interdisciplinary problems arise when dealing with complex mathematical formulations, numerical algorithms and their implementations on modern computer architectures. Therefore new frameworks are needed for sharing knowledge, software codes, and datasets among scientists. Here we present the Volcano Modelling and Simulation gateway (VMSg, accessible at http://vmsg.pi.ingv.it), a new electronic infrastructure for promoting knowledge growth and transfer in the field of volcanological modelling and numerical simulation. The new web portal, developed in the framework of former and ongoing national and European projects, is based on a dynamic Content Manager System (CMS) and was developed to host and present numerical models of the main volcanic processes and relationships including magma properties, magma chamber dynamics, conduit flow, plume dynamics, pyroclastic flows, lava flows, etc. Model applications, numerical code documentation, simulation datasets as well as model validation and calibration test-cases are also part of the gateway material.
NASA Astrophysics Data System (ADS)
Meinke, Insa
2017-06-01
In this article the comparability of knowledge transfer activities is discussed by accounting for external impacts. It is shown that factors which are neither part of the knowledge transfer activity nor part of the participating institution may have significant impact on the potential usefulness of knowledge transfer activities. Differences in the potential usefulness are leading to different initial conditions of the knowledge transfer activities. This needs to be taken into account when comparing different knowledge transfer activities, e.g., in program evaluations. This study is focusing on regional climate services at the German Baltic Sea coast. It is based on two surveys and experiences with two identical web tools applied on two regions with different spatial coverage. The results show that comparability among science based knowledge transfer activities is strongly limited through several external impacts. The potential usefulness and thus the initial condition of a particular knowledge transfer activity strongly depends on (1) the perceived priority of the focused topic, (2) the used information channels, (3) the conformity between the research agenda of service providing institutions and information demands in the public, as well as (4) on the spatial coverage of a service. It is suggested to account for the described external impacts for evaluations of knowledge transfer activities. The results show that the comparability of knowledge transfer activities is limited and challenge the adequacy of quantitative measures in this context. Moreover, as shown in this case study, in particular regional climate services should be individually evaluated on a long term perspective, by potential user groups and/or by its real users. It is further suggested that evaluation criteria should be co-developed with these stakeholder groups.
Mechanism of vibrational energy dissipation of free OH groups at the air-water interface.
Hsieh, Cho-Shuen; Campen, R Kramer; Okuno, Masanari; Backus, Ellen H G; Nagata, Yuki; Bonn, Mischa
2013-11-19
Interfaces of liquid water play a critical role in a wide variety of processes that occur in biology, a variety of technologies, and the environment. Many macroscopic observations clarify that the properties of liquid water interfaces significantly differ from those of the bulk liquid. In addition to interfacial molecular structure, knowledge of the rates and mechanisms of the relaxation of excess vibrational energy is indispensable to fully understand physical and chemical processes of water and aqueous solutions, such as chemical reaction rates and pathways, proton transfer, and hydrogen bond dynamics. Here we elucidate the rate and mechanism of vibrational energy dissipation of water molecules at the air-water interface using femtosecond two-color IR-pump/vibrational sum-frequency probe spectroscopy. Vibrational relaxation of nonhydrogen-bonded OH groups occurs at a subpicosecond timescale in a manner fundamentally different from hydrogen-bonded OH groups in bulk, through two competing mechanisms: intramolecular energy transfer and ultrafast reorientational motion that leads to free OH groups becoming hydrogen bonded. Both pathways effectively lead to the transfer of the excited vibrational modes from free to hydrogen-bonded OH groups, from which relaxation readily occurs. Of the overall relaxation rate of interfacial free OH groups at the air-H2O interface, two-thirds are accounted for by intramolecular energy transfer, whereas the remaining one-third is dominated by the reorientational motion. These findings not only shed light on vibrational energy dynamics of interfacial water, but also contribute to our understanding of the impact of structural and vibrational dynamics on the vibrational sum-frequency line shapes of aqueous interfaces.
Mechanism of vibrational energy dissipation of free OH groups at the air–water interface
Hsieh, Cho-Shuen; Campen, R. Kramer; Okuno, Masanari; Backus, Ellen H. G.; Nagata, Yuki; Bonn, Mischa
2013-01-01
Interfaces of liquid water play a critical role in a wide variety of processes that occur in biology, a variety of technologies, and the environment. Many macroscopic observations clarify that the properties of liquid water interfaces significantly differ from those of the bulk liquid. In addition to interfacial molecular structure, knowledge of the rates and mechanisms of the relaxation of excess vibrational energy is indispensable to fully understand physical and chemical processes of water and aqueous solutions, such as chemical reaction rates and pathways, proton transfer, and hydrogen bond dynamics. Here we elucidate the rate and mechanism of vibrational energy dissipation of water molecules at the air–water interface using femtosecond two-color IR-pump/vibrational sum-frequency probe spectroscopy. Vibrational relaxation of nonhydrogen-bonded OH groups occurs at a subpicosecond timescale in a manner fundamentally different from hydrogen-bonded OH groups in bulk, through two competing mechanisms: intramolecular energy transfer and ultrafast reorientational motion that leads to free OH groups becoming hydrogen bonded. Both pathways effectively lead to the transfer of the excited vibrational modes from free to hydrogen-bonded OH groups, from which relaxation readily occurs. Of the overall relaxation rate of interfacial free OH groups at the air–H2O interface, two-thirds are accounted for by intramolecular energy transfer, whereas the remaining one-third is dominated by the reorientational motion. These findings not only shed light on vibrational energy dynamics of interfacial water, but also contribute to our understanding of the impact of structural and vibrational dynamics on the vibrational sum-frequency line shapes of aqueous interfaces. PMID:24191016
Jahn, Rosa; Müller, Olaf; Bozorgmehr, Kayvan
2015-08-19
Universities, public institutions, and the transfer of knowledge to the private sector play a major role in the development of medical technologies. The decisions of universities and public institutions regarding the transfer of knowledge impact the accessibility of the final product, making it easier or more difficult for consumers to access these products. In the case of medical research, these products are pharmaceuticals, diagnostics, or medical procedures. The ethical dimension of access to these potentially lifesaving products is apparent and distinguishes the transfer of medical knowledge from the transfer of knowledge in other areas. While the general field of technology transfer from academic and public to private actors is attracting an increasing amount of scholarly attention, the specifications of knowledge transfer in the medical field are not as well explored. This review seeks to provide a systematic overview and analysis of the qualitative literature on the characteristics and determinants of knowledge transfer in medical research and development. The review systematically searches the literature for qualitative studies that focus on knowledge transfer characteristics and determinants at medical academic and public research institutions. It aims at identifying and analyzing the literature on the content and context of knowledge transfer policies, decision-making processes, and actors at academic and public institutions. The search strategy includes the databases PubMed, Web of Science, ProQuest, and DiVa. These databases will be searched based on pre-specified search terms. The studies selected for inclusion in the review will be critically assessed for their quality utilizing the Qualitative Research Checklist developed by the Clinical Appraisal Skills Programme. Data extraction and synthesis will be based on the meta-ethnographic approach. This review seeks to further the understanding of the kinds of transfer pathways that exist in medical knowledge transfer as well as what factors lead to the adoption of one pathway over another. The aim is to provide evidence for political and academic actors designing policies for the translation of medical knowledge and public-private cooperation. PROSPERO CRD42015014241 .
Rütten, A; Wolff, A; Streber, A
2016-03-01
This article discusses 2 current issues in the field of public health research: (i) transfer of scientific knowledge into practice and (ii) sustainable implementation of good practice projects. It also supports integration of scientific and practice-based evidence production. Furthermore, it supports utilisation of interactive models that transcend deductive approaches to the process of knowledge transfer. Existing theoretical approaches, pilot studies and thoughtful conceptual considerations are incorporated into a framework showing the interplay of science, politics and prevention practice, which fosters a more sustainable implementation of health promotion programmes. The framework depicts 4 key processes of interaction between science and prevention practice: interactive knowledge to action, capacity building, programme adaptation and adaptation of the implementation context. Ensuring sustainability of health promotion programmes requires a concentrated process of integrating scientific and practice-based evidence production in the context of implementation. Central to the integration process is the approach of interactive knowledge to action, which especially benefits from capacity building processes that facilitate participation and systematic interaction between relevant stakeholders. Intense cooperation also induces a dynamic interaction between multiple actors and components such as health promotion programmes, target groups, relevant organisations and social, cultural and political contexts. The reciprocal adaptation of programmes and key components of the implementation context can foster effectiveness and sustainability of programmes. Sustainable implementation of evidence-based health promotion programmes requires alternatives to recent deductive models of knowledge transfer. Interactive approaches prove to be promising alternatives. Simultaneously, they change the responsibilities of science, policy and public health practice. Existing boundaries within disciplines and sectors are overcome by arranging transdisciplinary teams as well as by developing common agendas and procedures. Such approaches also require adaptations of the structure of research projects such as extending the length of funding. © Georg Thieme Verlag KG Stuttgart · New York.
Tsai, Ming-Tien; Tsai, Ling-Long
2005-11-01
Nursing practise plays an important role in transferring nursing knowledge to nursing students. From the related literature review, prior knowledge will affect how learners gain new knowledge. There has been no direct examination of the prior knowledge interaction effect on students' performance and its influence on nursing students when evaluating the knowledge transfer success factors. This study explores (1) the critical success factors in transferring nursing knowledge, (2) the impact of prior knowledge when evaluating the success factors for transferring nursing knowledge. This research utilizes in-depth interviews to probe the initial success factor phase. A total of 422 valid questionnaires were conducted by the authors. The data were analysed by comparing the mean score and t-test between two groups. Seventeen critical success factors were identified by the two groups of students. Twelve items were selected to examine the diversity in the two groups. Students with prior knowledge were more independent than the other group. They also preferred self-directed learning over students without prior knowledge. Students who did not have prior knowledge were eager to take every opportunity to gain experience and more readily adopted new knowledge.
Cardiorespiratory Information Dynamics during Mental Arithmetic and Sustained Attention
Widjaja, Devy; Montalto, Alessandro; Vlemincx, Elke; Marinazzo, Daniele; Van Huffel, Sabine; Faes, Luca
2015-01-01
An analysis of cardiorespiratory dynamics during mental arithmetic, which induces stress, and sustained attention was conducted using information theory. The information storage and internal information of heart rate variability (HRV) were determined respectively as the self-entropy of the tachogram, and the self-entropy of the tachogram conditioned to the knowledge of respiration. The information transfer and cross information from respiration to HRV were assessed as the transfer and cross-entropy, both measures of cardiorespiratory coupling. These information-theoretic measures identified significant nonlinearities in the cardiorespiratory time series. Additionally, it was shown that, although mental stress is related to a reduction in vagal activity, no difference in cardiorespiratory coupling was found when several mental states (rest, mental stress, sustained attention) are compared. However, the self-entropy of HRV conditioned to respiration was very informative to study the predictability of RR interval series during mental tasks, and showed higher predictability during mental arithmetic compared to sustained attention or rest. PMID:26042824
The role of identification in dynamic psychiatry and psychotherapy.
Corradi, Richard B
2011-01-01
Identification-a psychic process in which a person takes on characteristics of another-is a concept important to the understanding of human nature. It plays an important role in how our personalities develop, in our ability to deal with life's stresses, and in how we interact with other people. Knowledge of its manifestations is essential to dynamic psychiatry and to its applications in psychotherapy. This article defines identification and reviews its role in development and as a defense. It discusses its role in the psychopathology of disorders commonly encountered in psychotherapy practice-depression and anxiety states reactive to losses in life, and borderline states. Clinical vignettes illustrate how identification functions in these conditions, and also how identifications reveal themselves in the transference and are utilized in psychotherapy. A teaching vignette illustrates how important it is that residents learning the art of psychotherapy appreciate the therapeutic potential of identification. The article maintains that, although it often goes unrecognized, identification with the therapist is one of the most effective therapeutic devices in the transference.
Bridging the Gap in Knowledge Transfer between Academia and Practitioners
ERIC Educational Resources Information Center
Gera, Rajat
2012-01-01
Purpose: The paper intends to identify the causes or gaps in transfer of managerial knowledge between academia and practitioners and to develop a framework that overcomes the gaps through knowledge management, information technology and human resource practices. The paper aims to suggest a strategic approach based on the knowledge transfer cycle.…
Transference, counter-transference and repetition: some implications for nursing practice.
Jones, Alun C
2005-11-01
This discussion paper offers an introductory text for nurses and explores the psychoanalytic ideas of transference, counter-transference and repetition compulsion. Disguised case vignettes provide illustrations of the ideas as they might apply to nursing, including professional practice and occupational choice. The literature suggests that transference can be a source of creativity as well as destructiveness and influence important communications with oneself and others including the choice of nursing and other health professions as an occupation. Recognizing possibilities of transference, counter-transference along with repetitive patterns of behaviours, can help nurses of all specialities to address situations constructively by responding thoughtfully and appropriately. This discussion concludes with the suggestions that we know little about the motivational factors underlying nursing as an occupational preference; moreover, nursing does not have a culture of personal therapy. As such nurses are denied opportunities to understand the possible reasons underlying their occupational choice or gain experiential knowledge of interpersonal dynamics occurring between patients and colleagues. Transference and counter-transference are thought to have some bearing on all relationships. Forming a natural part of the way human beings relate to each other, transference and counter-transference can bring about sincere human interest, caring and concern. However, there is also potential for disagreements. Recognizing the possible origins of relational difficulties can offer opportunities for professional development to nurses along with the benefits for health service users.
Incomplete Multisource Transfer Learning.
Ding, Zhengming; Shao, Ming; Fu, Yun
2018-02-01
Transfer learning is generally exploited to adapt well-established source knowledge for learning tasks in weakly labeled or unlabeled target domain. Nowadays, it is common to see multiple sources available for knowledge transfer, each of which, however, may not include complete classes information of the target domain. Naively merging multiple sources together would lead to inferior results due to the large divergence among multiple sources. In this paper, we attempt to utilize incomplete multiple sources for effective knowledge transfer to facilitate the learning task in target domain. To this end, we propose an incomplete multisource transfer learning through two directional knowledge transfer, i.e., cross-domain transfer from each source to target, and cross-source transfer. In particular, in cross-domain direction, we deploy latent low-rank transfer learning guided by iterative structure learning to transfer knowledge from each single source to target domain. This practice reinforces to compensate for any missing data in each source by the complete target data. While in cross-source direction, unsupervised manifold regularizer and effective multisource alignment are explored to jointly compensate for missing data from one portion of source to another. In this way, both marginal and conditional distribution discrepancy in two directions would be mitigated. Experimental results on standard cross-domain benchmarks and synthetic data sets demonstrate the effectiveness of our proposed model in knowledge transfer from incomplete multiple sources.
Kramer, Desré M; Wells, Richard P; Carlan, Nicolette; Aversa, Theresa; Bigelow, Philip P; Dixon, Shane M; McMillan, Keith
2013-01-01
Few evaluation tools are available to assess knowledge-transfer and exchange interventions. The objective of this paper is to develop and demonstrate a theory-based knowledge-transfer and exchange method of evaluation (KEME) that synthesizes 3 theoretical frameworks: the promoting action on research implementation of health services (PARiHS) model, the transtheoretical model of change, and a model of knowledge use. It proposes a new term, keme, to mean a unit of evidence-based transferable knowledge. The usefulness of the evaluation method is demonstrated with 4 occupational health and safety knowledge transfer and exchange (KTE) implementation case studies that are based upon the analysis of over 50 pre-existing interviews. The usefulness of the evaluation model has enabled us to better understand stakeholder feedback, frame our interpretation, and perform a more comprehensive evaluation of the knowledge use outcomes of our KTE efforts.
ERIC Educational Resources Information Center
Kuiken, Janna; van der Sijde, Peter
2011-01-01
The process of knowledge transfer has been extensively studied in the context of a variety of theoretical considerations. In this paper the authors adopt a communication theory perspective and focus on capacity for dissemination. Many studies assume that universities are able to disseminate and commercialize their knowledge (and technology).…
ERIC Educational Resources Information Center
Wu, Chien-Hsing; Kao, Shu-Chen; Shih, Lan-Hsin
2010-01-01
The transfer of tacit knowledge, one of the most important issues in the knowledge sharing context, needs a multi-dimensional perception in its process. Information technology's (IT) supporting role has already been addressed in the process of tacit knowledge transfer. However, IT has its own characteristics, and in turn, may have dissimilar…
Interkingdom transfer of the acne-causing agent, Propionibacterium acnes, from human to grapevine.
Campisano, Andrea; Ometto, Lino; Compant, Stéphane; Pancher, Michael; Antonielli, Livio; Yousaf, Sohail; Varotto, Claudio; Anfora, Gianfranco; Pertot, Ilaria; Sessitsch, Angela; Rota-Stabelli, Omar
2014-05-01
Here, we report the surprising and, to our knowledge, unique example of horizontal interkingdom transfer of a human opportunistic pathogen (Propionibacterium acnes) to a crop plant (the domesticated grapevine Vitis vinifera L.). Humans, like most organisms, have established a long-lasting cohabitation with a variety of microbes, including pathogens and gut-associated bacteria. Studies which have investigated the dynamics of such associations revealed numerous cases of bacterial host switches from domestic animals to humans. Much less is, however, known about the exchange of microbial symbionts between humans and plants. Fluorescent in situ hybridization localized P. acnes in the bark, in xylem fibers, and, more interestingly, inside pith tissues. Phylogenetic and population genetic analyses suggest that the establishment of the grapevine-associated P. acnes as obligate endophyte is compatible with a recent transfer event, likely during the Neolithic, when grapevine was domesticated.
Illuminating the processes of knowledge transfer in nursing.
Aita, Marilyn; Richer, Marie-Claire; Héon, Marjolaine
2007-01-01
Over the past 10 years, there has been a propensity to translate research findings and evidence into clinical practice, and concepts such as knowledge transfer, research dissemination, research utilization, and evidence-based practice have been described in the nursing literature. This manuscript shows a selective review of the definitions and utilization of these concepts and offers a perspective on their interrelationships by indicating how knowledge transfer processes are the basis of all the concepts under review. Definitions and utilization of knowledge transfer in the literature have been influenced by educational and social perspectives and indicate two important processes that are rooted in the mechanisms of research dissemination, research utilization, and evidence-based practice. These processes refer to a cognitive and an interpersonal dimension. Knowledge transfer underlies a process involving cognitive resources as well as an interpersonal process where the knowledge is transferred between individuals or groups of individuals. This manuscript can contribute to our understanding of the theoretical foundations linking these concepts and these processes by comparing and contrasting them. It also shows the value and empirical importance of the cognitive and interpersonal processes of knowledge transfer by which research findings and evidence can be successfully translated and implemented into the nursing clinical practice.
NASA Astrophysics Data System (ADS)
Su, Shibin
As the lacks of existing research about intellectual property conflicts management of EC enterprise, the paper analysis the intellectual property conflicts in knowledge transferring among EC enterprises by intellectual property types, then, the paper makes research on intellectual property conflicts identification in knowledge transferring among EC enterprises, and gives relative assumption, meanwhile, the paper makes quantities identification of intellectual property conflicts in knowledge transferring among EC enterprises by evidential theory, finally, the paper gives the further research orientations.
Selective automation and skill transfer in medical robotics: a demonstration on surgical knot-tying.
Knoll, Alois; Mayer, Hermann; Staub, Christoph; Bauernschmitt, Robert
2012-12-01
Transferring non-trivial human manipulation skills to robot systems is a challenging task. There have been a number of attempts to design research systems for skill transfer, but the level of the complexity of the actual skills transferable to the robot was rather limited, and delicate operations requiring a high dexterity and long action sequences with many sub-operations were impossible to transfer. A novel approach to human-machine skill transfer for multi-arm robot systems is presented. The methodology capitalizes on the metaphor of 'scaffolded learning', which has gained widespread acceptance in psychology. The main idea is to formalize the superior knowledge of a teacher in a certain way to generate support for a trainee. In our case, the scaffolding is constituted by abstract patterns, which facilitate the structuring and segmentation of information during 'learning by demonstration'. The actual skill generalization is then based on simulating fluid dynamics. The approach has been successfully evaluated in the medical domain for the delicate task of automated knot-tying for suturing with standard surgical instruments and a realistic minimally invasive robotic surgery system. Copyright © 2012 John Wiley & Sons, Ltd.
Knowledge Transfer Project: Cultivating Smart Energy Solutions through Dynamic Peer-to-Peer Learning
DOE Office of Scientific and Technical Information (OSTI.GOV)
As energy policy makers and professionals convene in the Oresund region for the 9th Annual Clean Energy Ministerial (CEM9), the global community is as united as ever around the common goal of accelerating the transition to global clean energy. Through sustained collective effort and thought leadership, CEM partners and stakeholders are systematically addressing the barriers to the widescale deployment of clean energy technologies. Pivotal to their progress is the efficient sharing and dissemination of knowledge. To address that need, the CEM-initiative International SmartGrid Action Network (ISGAN) launched the Knowledge Transfer Project (KTP) in March 2016 to capture, collect, and sharemore » knowledge about smart grid technologies among countries and key stakeholders. Building on ISGAN's experience with delivering deep-dive workshops, the KTP fosters meaningful international dialogue on smart grids with a focus on developing competence and building capacity. After a successful 2016 pilot project and two consecutive projects, each with a different focus and structure, the KTP has become an established practice that can support existing ISGAN or CEM initiatives. To accommodate different purposes, needs, and practical circumstances, ISGAN has adopted three basic models for delivering KTP workshops: Country-Centric, Multilateral, and Hybrid. This fact sheet describes each approach through case studies of workshops in Mexico, India, and Belgium, and invites new ideas and partners for future KTPs.« less
Siron, Stéphanie; Dagenais, Christian; Ridde, Valéry
2015-11-01
This study describes the current state of research on knowledge transfer strategies to improve public health in low-income countries, to identify the knowledge gaps on this topic. In this scoping review, a descriptive and systematic process was used to analyse, for each article retained, descriptions of research context and methods, types of knowledge transfer activities and results reported. 28 articles were analysed. They dealt with the evaluation of transfer strategies that employed multiple activities, mostly targeting health professionals and women with very young children. Most often these studies used quantitative designs and measurements of instrumental use with some methodological shortcomings. Results were positive and suggested recommendations for improving professional practices, knowledge and health-related behaviours. The review highlights the great diversity of transfer strategies used, strategies and many conditions for knowledge use. The review provides specific elements for understanding the transfer processes in low-income countries and highlights the need for systematic evaluation of the conditions for research results utilization.
NASA Astrophysics Data System (ADS)
Arsawan, I. W. E.; Sanjaya, I. B.; Putra, I. K. M.; Sukarta, I. W.
2018-01-01
This study aims to examine the relationship between motivation and knowledge transfer to the subsidiaries performance and test the role of absorptive capacity as a moderating variable. The research uses quantitative design through questionnaires distribution with 5 Likert scales. The population frame is five-star hotel in Bali province, Indonesia which amounted to 63 units, the sample of research using proportional random sampling is 54 units and determined the distribution of questionnaires to 162 subsidiaries as the unit of analysis. The research model was built using the structural equation model and analyzed with smart pls- 3 software. The findings of the study revealed that subsidiaries motivation a significant effect on knowledge transfer, knowledge transfer a significant effect on subsidiaries performance, motivation a significant effect on subsidiaries performance and absorptive capacity moderated the relationship between knowledge transfer and subsidiaries performance. These findings suggest that subsidiaries and process of knowledge transfer through absorptive capacity play an important role, and that they have some impact on the subsidiaries performance.
Characterizing Gas Transport in Wetland Soil-Root Systems with Dissolved Gas Tracer Techniques
NASA Astrophysics Data System (ADS)
Reid, M. C.; Jaffe, P. R.
2016-12-01
Soil fluxes of methane (CH4), nitrous oxide (N2O), and other biogenic gases depend on coupling between microbial and physiochemical processes within soil media. The importance of plant-mediated transport in wetland CH4 emissions is well known, but a generalized understanding of gas transfer between pore water and root aerenchyma, and how this process competes with biogeochemical production/consumption of gases beyond CH4, is incomplete [1]. A lack of experimental approaches to characterize transport processes in complex soil-water-plant systems at field scale has limited efforts to close this knowledge gap. In this presentation we describe dissolved gas tracer techniques to tease apart effects of transport from simultaneous biochemical reaction on trace gas dynamics in soils. We discuss a push-pull test with helium and sulfur hexafluoride gas tracers to quantify in situ root-mediated gas transfer kinetics in a wetland soil [2]. A Damköhler number analysis is introduced to interpret the results and evaluate the balance between biochemical reaction and root-driven gas transfer in controlling the fate of CH4 and N2O in vegetated wetland soils. We conclude with a brief discussion of other problems in soil gas dynamics that can be addressed with gas tracer approaches. [1] Blagodatsky and Smith 2012. Soil physics meets soil biology: Towards better mechanistic prediction of greenhouse gas emissions from soil. Soil Biology and Biochemistry 47, 78-92. [2] Reid et al. 2015. Dissolved gas dynamics in wetland soils: Root-mediated gas transfer kinetics determind via push-pull tracer tests. Water Resour. Res. 51, doi:10.1002/2014WR016803.
ERIC Educational Resources Information Center
Sutrisno, Agustian; Pillay, Hitendra
2015-01-01
As transnational programs are often advocated as a knowledge transfer opportunity between the partner universities, this case study investigated the knowledge transfer (KT) processes between Indonesian and Australian universities through an undergraduate transnational program partnership (TPP). An inter-organisational KT theoretical framework from…
Factors shaping the evolution of electronic documentation systems
NASA Technical Reports Server (NTRS)
Dede, Christopher J.; Sullivan, Tim R.; Scace, Jacque R.
1990-01-01
The main goal is to prepare the space station technical and managerial structure for likely changes in the creation, capture, transfer, and utilization of knowledge. By anticipating advances, the design of Space Station Project (SSP) information systems can be tailored to facilitate a progression of increasingly sophisticated strategies as the space station evolves. Future generations of advanced information systems will use increases in power to deliver environmentally meaningful, contextually targeted, interconnected data (knowledge). The concept of a Knowledge Base Management System is emerging when the problem is focused on how information systems can perform such a conversion of raw data. Such a system would include traditional management functions for large space databases. Added artificial intelligence features might encompass co-existing knowledge representation schemes; effective control structures for deductive, plausible, and inductive reasoning; means for knowledge acquisition, refinement, and validation; explanation facilities; and dynamic human intervention. The major areas covered include: alternative knowledge representation approaches; advanced user interface capabilities; computer-supported cooperative work; the evolution of information system hardware; standardization, compatibility, and connectivity; and organizational impacts of information intensive environments.
NASA Technical Reports Server (NTRS)
Zoladz, Tom; Patel, Sandeep; Lee, Erik; Karon, Dave
2011-01-01
Experimental results describing the hydraulic dynamic pump transfer matrix (Yp) for a cavitating J-2X oxidizer turbopump inducer+impeller tested in subscale waterflow are presented. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Dynamic transfer functions across widely varying pump hydrodynamic inlet conditions are extracted from measured data in conjunction with 1D-model based corrections. Derived Dynamic transfer functions are initially interpreted relative to traditional Pogo pump equations. Water-to-liquid oxygen scaling of measured cavitation characteristics are discussed. Comparison of key dynamic transfer matrix terms derived from waterflow testing are made with those implemented in preliminary Ares Upper Stage Pogo stability modeling. Alternate cavitating pump hydraulic dynamic equations are suggested which better reflect frequency dependencies of measured transfer matrices.
Inter-Individual Knowledge Transfer and Performance in Product Development
ERIC Educational Resources Information Center
Kumar, Ajith; Ganesh, L. S.
2011-01-01
Purpose: This paper aims to examine how knowledge transfer between individuals influences performance in product development (PD) organizations and whether this influence is contingent to the degree of novelty in the PD work. Design/methodology/approach: A set of hypotheses describing the relationships between knowledge transfer by codification…
Communication, Constructivism, and Transfer of Knowledge in the Education of Bilingual Learners.
ERIC Educational Resources Information Center
Olivares, Rafael A.
2002-01-01
Discusses a theoretical framework to educate bilingual learners that links the communicative approach and the constructivist approach to learning with the transfer of knowledge from one language to another. The framework is illustrated in the communication, constructivism, and transference of knowledge (CCT) model where bilingual students use…
Kawashima, Yukio; Tachikawa, Masanori
2014-01-14
Ab initio path integral molecular dynamics (PIMD) simulation was performed to understand the nuclear quantum effect on the out-of-plane ring deformation of hydrogen maleate anion and investigate the existence of a stable structure with ring deformation, which was suggested in experimental observation (Fillaux et al., Chem. Phys. 1999, 120, 387-403). The isotope effect and the temperature effect are studied as well. We first investigated the nuclear quantum effect on the proton transfer. In static calculation and classical ab initio molecular dynamics simulations, the proton in the hydrogen bond is localized to either oxygen atom. On the other hand, the proton is located at the center of two oxygen atoms in quantum ab initio PIMD simulations. The nuclear quantum effect washes out the barrier of proton transfer. We next examined the nuclear quantum effect on the motion of hydrogen maleate anion. Principal component analysis revealed that the out-of-plane ring bending modes have dominant contribution to the entire molecular motion. In quantum ab initio PIMD simulations, structures with ring deformation were the global minimum for the deuterated isotope at 300 K. We analyzed the out-of-plane ring bending mode further and found that there are three minima along a ring distortion mode. We successfully found a stable structure with ring deformation of hydrogen maleate for the first time, to our knowledge, using theoretical calculation. The structures with ring deformation found in quantum simulation of the deuterated isotope allowed the proton transfer to occur more frequently than the planar structure. Static ab initio electronic structure calculation found that the structures with ring deformation have very small proton transfer barrier compared to the planar structure. We suggest that the "proton transfer driven" mechanism is the origin of stabilization for the structure with out-of-plane ring deformation.
The effects of legacy organization culture on post-merger integration.
Frantz, Terrill L; Carley, Kathleen M
2013-01-01
We explore the relationship between the characteristics of pre-existing organization cultures and post-merger integration dynamics; this study involves examining data produced by computer simulation. Two characteristics of organization culture, its characteristic complexity and its propensity for members' to share information, are controlled in computational experiments. To characterize post-merger integration dynamics, we measure the transfer of information with respect to two types: (a) that which is necessary in performing work tasks, and (b) that which underlies the features of a group's culture. The extent to which this information is common in a group is indicative of task performance and the cultural cohesiveness of its members; leading to the level of performance for the group. We consider cultural knowledge as it pertains to both that of the entire organization and at the work-team level; often times, these can be dissimilar. We find that cultural complexity and exchange motivation vary in their influence on the diffusion of task and cultural knowledge: the more complex the culture, the longer for post-merger integration to complete, while simultaneously task performance suffers. However, the inclination for an organization to energetically share their culture with another group does not immensely impact the diffusion of cultural or task knowledge; moreover, high levels of task focus in a culture can hinder cultural diffusion, though performance is positively correlated with this characteristic. This study has relevance to post-merger integration research and practice by providing a theoretically grounded, quantitative model useful for estimating the post-merger dynamics of cultural awareness and knowledge diffusion for a specific merger situation.
Knowledge service decision making in business incubators based on the supernetwork model
NASA Astrophysics Data System (ADS)
Zhao, Liming; Zhang, Haihong; Wu, Wenqing
2017-08-01
As valuable resources for incubating firms, knowledge resources have received gradually increasing attention from all types of business incubators, and business incubators use a variety of knowledge services to stimulate rapid growth in incubating firms. Based on previous research, we generalize the knowledge transfer and knowledge networking services of two main forms of knowledge services and further divide knowledge transfer services into knowledge depth services and knowledge breadth services. Then, we construct the business incubators' knowledge supernetwork model, describe the evolution mechanism among heterogeneous agents and utilize a simulation to explore the performance variance of different business incubators' knowledge services. The simulation results show that knowledge stock increases faster when business incubators are able to provide knowledge services to more incubating firms and that the degree of discrepancy in the knowledge stock increases during the process of knowledge growth. Further, knowledge transfer services lead to greater differences in the knowledge structure, while knowledge networking services lead to smaller differences. Regarding the two types of knowledge transfer services, knowledge depth services are more conducive to knowledge growth than knowledge breadth services, but knowledge depth services lead to greater gaps in knowledge stocks and greater differences in knowledge structures. Overall, it is optimal for business incubators to select a single knowledge service or portfolio strategy based on the amount of time and energy expended on the two types of knowledge services.
Case Study: The Transfer of Tacit Knowledge from Community College Full-Time to Adjunct Faculty
ERIC Educational Resources Information Center
Guzzo, Linda R.
2013-01-01
Knowledge is a valuable resource that fosters innovation and growth in organizations. There are two forms of knowledge: explicit knowledge or documented information and tacit knowledge or undocumented information which resides in individuals' minds. There is heightened interest in knowledge management and specifically the transfer of tacit…
ERIC Educational Resources Information Center
Fongwa, Neba Samuel; Marais, Lochner
2016-01-01
The role of knowledge in the current knowledge economy cannot be overly emphasised. Successful regions are continuously being linked to excellence in the production, accumulation, and application of knowledge. Universities have increasingly been at the centre of such knowledge production, application and transfer. Yet, there is little research and…
ERIC Educational Resources Information Center
Ottoson, Judith M.
2009-01-01
Five knowledge-for-action theories are summarized and compared in this chapter for their evaluation implications: knowledge utilization, diffusion, implementation, transfer, and translation. Usually dispersed across multiple fields and disciplines, these theories are gathered here for a common focus on knowledge and change. Knowledge in some form…
NASA Astrophysics Data System (ADS)
Pino, Abdiel O.; Pladellorens, Josep
2014-07-01
A means of facilitating the transfer of Optical inspection methods knowledge and skills from academic institutions and their research partners into Panama optics and optical research groups is described. The process involves the creation of an Integrated Knowledge Group Research (IKGR), a partnership led by Polytechnic University of Panama with the support of the SENACYT and Optics and Optometry Department, Polytechnic University of Catalonia. This paper describes the development of the Project for knowledge transfer "Implementation of a method of optical inspection of low cost for improving the surface quality of rolled material of metallic and nonmetallic industrial use", this project will develop a method for measuring the surface quality using texture analysis speckle pattern formed on the surface to be characterized. The project is designed to address the shortage of key skills in the field of precision engineering for optical applications. The main issues encountered during the development of the knowledge transfer teaching and learning are discussed, and the outcomes from the first four months of knowledge transfer activities are described. In overall summary, the results demonstrate how the Integrated Knowledge Group Research and new approach to knowledge transfer has been effective in addressing the engineering skills gap in precision optics for manufactured industrial sector.
77 FR 5580 - Notice of Intent To Seek Approval To Extend an Information Collection
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-03
... Program supports innovation in the integrative conduct of research, education and knowledge transfer... disciplines, weaving together knowledge creation, knowledge integration, and knowledge transfer. STCs conduct... organizations, and/or other public/private entities. New knowledge thus created is meaningfully linked to...
Supporting the Transference of Knowledge about Language within Teacher Education Programs
ERIC Educational Resources Information Center
Fenwick, Lisl; Endicott, Michele; Quinn, Marie; Humphrey, Sally
2014-01-01
Teacher education is effective when pre-service teachers are able to transfer knowledge from content areas to practice. This study investigates the extent to which curriculum and assessment designs, along with teaching practices, supported pre-service teachers to transfer knowledge gained about language from a first-year course into a second-year…
ERIC Educational Resources Information Center
Guldberg, Karen; Parsons, Sarah; Porayska-Pomsta, Kaska; Keay-Bright, Wendy
2017-01-01
Experimental intervention studies constitute the current dominant research designs in the autism education field. Such designs are based on a "knowledge-transfer" model of evidence-based practice in which research is conducted by researchers, and is then "transferred" to practitioners to enable them to implement evidence-based…
Tacit Knowledge Barriers within Franchise Organizations
ERIC Educational Resources Information Center
Cumberland, Denise M.; Githens, Rod P.
2010-01-01
This paper reviews knowledge management in the context of a franchise business operation, with a focus on tacit knowledge barriers. In a franchise organization, the transfer of knowledge occurs on multiple levels and has an added level of complexity because of the number of partners and relationships. Tacit knowledge transfer should occur…
Personalized Knowledge Transfer for Caregiving Relatives.
Wolff, Dominik; Behrends, Marianne; Gerlach, Mario; Kupka, Thomas; Marschollek, Michael
2018-01-01
Caregiving relatives have to manage very diverse tasks and need a lot of care-relevant knowledge. For most of them it is not easy to find the knowledge required. Thus, a personalized knowledge transfer for caregiving relatives is necessary. Against this background, methods to determine the personal relevance and importance of knowledge resources for caregiving relatives are developed. To evaluate these methods, an exemplary fictitious person is created by experts in Nursing Science. In this evaluation, the approach's results are compared with an expert opinion. The approach indicates that a personalized knowledge transfer is possible, providing caregiving relatives with necessary care knowledge according to their personal life situation.
Problem-Based Learning: A Learning Environment for Enhancing Learning Transfer
ERIC Educational Resources Information Center
Hung, Woei
2013-01-01
Knowledge application and transfer is one of the ultimate learning goals in education. For adult learners, these abilities are not only beneficial but also critical. The ability to apply knowledge learned from school is only a basic requirement in workplaces. In this ever-changing world, the ability to near and far transfer knowledge is the skill…
Exploring Hurdles to Transfer: Student Experiences of Applying Knowledge across Disciplines
ERIC Educational Resources Information Center
Lappalainen, Jouni; Rosqvist, Juho
2015-01-01
This paper explores the ways students perceive the transfer of learned knowledge to new situations -- often a surprisingly difficult prospect. The novel aspect compared to the traditional transfer studies is that the learning phase is not a part of the experiment itself. The intention was only to activate acquired knowledge relevant to the…
Enhancing Transfer of Knowledge in Physics through Effective Teaching Strategies
ERIC Educational Resources Information Center
Akinbobola, Akinyemi Olufunminiyi
2015-01-01
The study assessed the enhancement of transfer of knowledge in physics through the use of effective teaching strategies in Nigerian senior secondary schools. Non-randomized pretest-posttest control group design was adopted for the study. A total of 278 physics students took part in the study. Transfer of Knowledge Test in Physics (TKTP) with the…
ERIC Educational Resources Information Center
Lucas, Leyland M.; Ogilvie, D. T.
2006-01-01
Purpose: The purpose of this paper is to illuminate the question "given all that we know about knowledge transfer in organizations, why do problems persist?" This is achieved by examining the challenges confronting organizations in developing an effective knowledge transfer strategy. Design/methodology/approach: A questionnaire was administered to…
Technology and Knowledge Transfer in the Graz Region Ten Years of Experience
ERIC Educational Resources Information Center
Hofer, Franz; Adametz, Christoph; Holzer, Franz
2004-01-01
Technology and knowledge transfer from universities to small and medium-sized enterprises (SMEs) is seen as one way to strengthen a region's innovation capability. But what if SMEs do not want to play along? Looking back at some 10 years' experience of supporting SMEs, the authors describe in detail the 'Active Knowledge Transfer' programme, which…
The Governance of University Knowledge Transfer: A Critical Review of the Literature
ERIC Educational Resources Information Center
Geuna, Aldo; Muscio, Alessandro
2009-01-01
Universities have long been involved in knowledge transfer activities. Yet the last 30 years have seen major changes in the governance of university-industry interactions. Knowledge transfer has become a strategic issue: as a source of funding for university research and (rightly or wrongly) as a policy tool for economic development. Universities…
ERIC Educational Resources Information Center
Sharifi, Hossein; Liu, Weisheng; Ismail, Hossam S.
2014-01-01
Higher education institutions (HEIs) have become increasingly entrepreneurial. Such a shift is highly dependent on the managers of university knowledge transfer offices whose perceptions can be critical in this transformation. This study examines such senior managers' perceptions concerning the "open" paradigm in relation with the…
ERIC Educational Resources Information Center
Hurtado, Ghaffar Ali
2014-01-01
The purpose of this study was to investigate the process of knowledge transfer. The setting is a health and nutrition educational program at University of Minnesota Extension. The main research question was how is Knowledge Transfer being implemented in Extension, specifically Educational Supplemental Nutrition Assistance Program? A case study,…
Exploring "Transnational" University Cooperation in Knowledge Transfer: A European Perspective
ERIC Educational Resources Information Center
van der Heide, Sjors; van der Sijde, Peter; Terlouw, Cees
2010-01-01
The dissemination and transfer of knowledge are an important source of value-added in research activities, and the transfer of new knowledge to society is now seen as a key responsibility of universities. Transnational research cooperation is pivotal to European research funding and, with this in mind, the authors examine the state of cooperation…
Diagnostic reasoning and underlying knowledge of students with preclinical patient contacts in PBL.
Diemers, Agnes D; van de Wiel, Margje W J; Scherpbier, Albert J J A; Baarveld, Frank; Dolmans, Diana H J M
2015-12-01
Medical experts have access to elaborate and integrated knowledge networks consisting of biomedical and clinical knowledge. These coherent knowledge networks enable them to generate more accurate diagnoses in a shorter time. However, students' knowledge networks are less organised and students have difficulties linking theory and practice and transferring acquired knowledge. Therefore we wanted to explore the development and transfer of knowledge of third-year preclinical students on a problem-based learning (PBL) course with real patient contacts. Before and after a 10-week PBL course with real patients, third-year medical students were asked to think out loud while diagnosing four types of paper patient problems (two course cases and two transfer cases), and explain the underlying pathophysiological mechanisms of the patient features. Diagnostic accuracy and time needed to think through the cases were measured. The think-aloud protocols were transcribed verbatim and different types of knowledge were coded and quantitatively analysed. The written pathophysiological explanations were translated into networks of concepts. Both the concepts and the links between concepts in students' networks were compared to model networks. Over the course diagnostic accuracy increased, case-processing time decreased, and students used less biomedical and clinical knowledge during diagnostic reasoning. The quality of the pathophysiological explanations increased: the students used more concepts, especially more model concepts, and they used fewer wrong concepts and links. The findings differed across course and transfer cases. The effects were generally less strong for transfer cases. Students' improved diagnostic accuracy and the improved quality of their knowledge networks suggest that integration of biomedical and clinical knowledge took place during a 10-week course. The differences between course and transfer cases demonstrate that transfer is complex and time-consuming. We therefore suggest offering students many varied patient contacts with the same underlying pathophysiological mechanism and encouraging students to link biomedical and clinical knowledge. © 2015 John Wiley & Sons Ltd.
Interface-induced phenomena in magnetism
Hellman, Frances; Hoffmann, Axel; Tserkovnyak, Yaroslav; ...
2017-06-05
Our article reviews static and dynamic interfacial effects in magnetism, focusing on interfacially-driven magnetic effects and phenomena associated with spin-orbit coupling and intrinsic symmetry breaking at interfaces. It provides a historical background and literature survey, but focuses on recent progress, identifying the most exciting new scientific results and pointing to promising future research directions. It starts with an introduction and overview of how basic magnetic properties are affected by interfaces, then turns to a discussion of charge and spin transport through and near interfaces and how these can be used to control the properties of the magnetic layer. Important conceptsmore » include spin accumulation, spin currents, spin transfer torque, and spin pumping. We provide an overview for the current state of knowledge and existing review literature on interfacial effects such as exchange bias, exchange spring magnets, spin Hall effect, oxide heterostructures, and topological insulators. Our article highlights recent discoveries of interface-induced magnetism and non-collinear spin textures, non-linear dynamics including spin torque transfer and magnetization reversal induced by interfaces, and interfacial effects in ultrafast magnetization processes.« less
Interface-Induced Phenomena in Magnetism
Hoffmann, Axel; Tserkovnyak, Yaroslav; Beach, Geoffrey S. D.; Fullerton, Eric E.; Leighton, Chris; MacDonald, Allan H.; Ralph, Daniel C.; Arena, Dario A.; Dürr, Hermann A.; Fischer, Peter; Grollier, Julie; Heremans, Joseph P.; Jungwirth, Tomas; Kimel, Alexey V.; Koopmans, Bert; Krivorotov, Ilya N.; May, Steven J.; Petford-Long, Amanda K.; Rondinelli, James M.; Samarth, Nitin; Schuller, Ivan K.; Slavin, Andrei N.; Stiles, Mark D.; Tchernyshyov, Oleg; Thiaville, André; Zink, Barry L.
2017-01-01
This article reviews static and dynamic interfacial effects in magnetism, focusing on interfacially-driven magnetic effects and phenomena associated with spin-orbit coupling and intrinsic symmetry breaking at interfaces. It provides a historical background and literature survey, but focuses on recent progress, identifying the most exciting new scientific results and pointing to promising future research directions. It starts with an introduction and overview of how basic magnetic properties are affected by interfaces, then turns to a discussion of charge and spin transport through and near interfaces and how these can be used to control the properties of the magnetic layer. Important concepts include spin accumulation, spin currents, spin transfer torque, and spin pumping. An overview is provided to the current state of knowledge and existing review literature on interfacial effects such as exchange bias, exchange spring magnets, spin Hall effect, oxide heterostructures, and topological insulators. The article highlights recent discoveries of interface-induced magnetism and non-collinear spin textures, non-linear dynamics including spin torque transfer and magnetization reversal induced by interfaces, and interfacial effects in ultrafast magnetization processes. PMID:28890576
Direct Observation of Photoexcited Hole Localization in CdSe Nanorods
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yang, Ye; Wu, Kaifeng; Shabaev, Andrew
Quantum-confined 1D semiconductor nanostructures are being investigated for hydrogen generation photocatalysts. In the photoreaction, after fast electron transfer, holes that remain in the nanostructure play an important role in the total quantum yield of hydrogen production. Unfortunately, knowledge of hole dynamics is limited due to lack of convenient spectroscopic signatures. Here, we directly probe hole localization dynamics within CdSe nanorods (NRs) by combining transient absorption (TA) and time-resolved terahertz (TRTS) spectroscopy. We show that when methylene blue is used as an electron acceptor, the resulting electron transfer occurs with a time constant of 3.5 +/- 0.1 ps and leaves behindmore » a delocalized hole. However, the hole quickly localizes in the Coulomb potential well generated by the reduced electron acceptor near the NR surface with time constant of 11.7 +/- 0.2 ps. Our theoretical investigation suggests that the hole becomes confined to a ~ +/-0.8 nm region near the reduced electron acceptor and the activation energy to detrap the hole from the potential well can be as large as 235 meV.« less
Metacognition and Transfer: Keys to Improving Marketing Education
ERIC Educational Resources Information Center
Ramocki, Stephen P.
2007-01-01
A primary purpose of marketing education is to prepare students to perform throughout their careers, and performance largely relies on transferability of knowledge. It has been demonstrated that training in metacognition, along with emphasis on transfer, does lead to increased probability that knowledge will be transferred into environments…
The Role of "Creative Transfer" in Professional Transitions
ERIC Educational Resources Information Center
Triantafyllaki, Angeliki
2016-01-01
This paper discusses the concept of "knowledge transfer" in terms of expansion of prior knowledge, creativity and approaches to generating new knowledge. It explores professional transitions in which knowledge restructuring and identity reformation are pathways into greater work flexibility and adjustment. Two studies, exploring…
ERIC Educational Resources Information Center
Sollie, Carlton R.; Howell, Frank M.
Issues and problems associated with university involvement in public sector activities and the knowledge transfer process are examined. After a brief statement of the state-of-the-art in knowledge transfer, attention is directed to one of the basic issues presented in the literature: the appropriateness and inappropriateness of university…
Classification of foods by transferring knowledge from ImageNet dataset
NASA Astrophysics Data System (ADS)
Heravi, Elnaz J.; Aghdam, Hamed H.; Puig, Domenec
2017-03-01
Automatic classification of foods is a way to control food intake and tackle with obesity. However, it is a challenging problem since foods are highly deformable and complex objects. Results on ImageNet dataset have revealed that Convolutional Neural Network has a great expressive power to model natural objects. Nonetheless, it is not trivial to train a ConvNet from scratch for classification of foods. This is due to the fact that ConvNets require large datasets and to our knowledge there is not a large public dataset of food for this purpose. Alternative solution is to transfer knowledge from trained ConvNets to the domain of foods. In this work, we study how transferable are state-of-art ConvNets to the task of food classification. We also propose a method for transferring knowledge from a bigger ConvNet to a smaller ConvNet by keeping its accuracy similar to the bigger ConvNet. Our experiments on UECFood256 datasets show that Googlenet, VGG and residual networks produce comparable results if we start transferring knowledge from appropriate layer. In addition, we show that our method is able to effectively transfer knowledge to the smaller ConvNet using unlabeled samples.
New Proposals for Generating and Exploiting Solution-Oriented Knowledge
ERIC Educational Resources Information Center
Gredig, Daniel; Sommerfeld, Peter
2008-01-01
The claim that professional social work should be based on scientific knowledge is many decades old with knowledge transfer usually moving in the direction from science to practice. The authors critique this model of knowledge transfer and support a hybrid one that places more of an emphasis on professional knowledge and action occurring in the…
ERIC Educational Resources Information Center
Harrington, Denis; Kearney, Arthur
2011-01-01
Purpose: This paper aims to consider the extent to which business school transition has created new opportunities in management development, knowledge transfer and knowledge creation. Design/methodology/approach: The paper is a critical review of knowledge exchange in a business school context with a particular focus on the "translation or…
Study of Anti-Vortex Baffle Effect in Suppressing Swirling Flow in LOX Tank
NASA Technical Reports Server (NTRS)
Yang, H. Q.; Peugeot, John
2011-01-01
Experimental results describing the hydraulic dynamic pump transfer matrix (Yp) for a cavitating J-2X oxidizer turbopump inducer+impeller tested in subscale waterflow are presented. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Dynamic transfer functions across widely varying pump hydrodynamic inlet conditions are extracted from measured data in conjunction with 1D-model based corrections. Derived Dynamic transfer functions are initially interpreted relative to traditional Pogo pump equations. Water-to-liquid oxygen scaling of measured cavitation characteristics are discussed. Comparison of key dynamic transfer matrix terms derived from waterflow testing are made with those implemented in preliminary Ares Upper Stage Pogo stability modeling. Alternate cavitating pump hydraulic dynamic equations are suggested which better reflect frequency dependencies of measured transfer matrices.
The impact of innovation intermediary on knowledge transfer
NASA Astrophysics Data System (ADS)
Lin, Min; Wei, Jun
2018-07-01
Many firms have opened up their innovation process and actively transfer knowledge with external partners in the market of technology. To reduce some of the market inefficiencies, more and more firms collaborate with innovation intermediaries. In light of the increasing importance of intermediary in the context of open innovation, we in this paper systematically investigate the effect of innovation intermediary on knowledge transfer and innovation process in networked systems. We find that the existence of innovation intermediary is conducive to the knowledge diffusion and facilitate the knowledge growth at system level. Interestingly, the scale of the innovation intermediary has little effect on the growth of knowledge. We further investigate the selection of intermediary members by comparing four selection strategies: random selection, initial knowledge level based selection, absorptive capability based selection, and innovative ability based selection. It is found that the selection strategy based on innovative ability outperforms all the other strategies in promoting the system knowledge growth. Our study provides a theoretical understanding of the impact of innovation intermediary on knowledge transfer and sheds light on the design and selection of innovation intermediary in open innovation.
Enzymatic Kinetic Isotope Effects from First-Principles Path Sampling Calculations.
Varga, Matthew J; Schwartz, Steven D
2016-04-12
In this study, we develop and test a method to determine the rate of particle transfer and kinetic isotope effects in enzymatic reactions, specifically yeast alcohol dehydrogenase (YADH), from first-principles. Transition path sampling (TPS) and normal mode centroid dynamics (CMD) are used to simulate these enzymatic reactions without knowledge of their reaction coordinates and with the inclusion of quantum effects, such as zero-point energy and tunneling, on the transferring particle. Though previous studies have used TPS to calculate reaction rate constants in various model and real systems, it has not been applied to a system as large as YADH. The calculated primary H/D kinetic isotope effect agrees with previously reported experimental results, within experimental error. The kinetic isotope effects calculated with this method correspond to the kinetic isotope effect of the transfer event itself. The results reported here show that the kinetic isotope effects calculated from first-principles, purely for barrier passage, can be used to predict experimental kinetic isotope effects in enzymatic systems.
Design-based science and the transfer of science knowledge and real-world problem-solving skills
NASA Astrophysics Data System (ADS)
Fortus, David Leon
Design-Based Science (DBS) helps students develop new scientific knowledge and problem-solving skills in the context of designing artifacts. This pedagogy was developed as a response to the potential problem of transfer of knowledge from academic settings to extra classroom environments. This dissertation describes DBS in detail and attempts to answer three questions: (1) Do DBS curricula support students' efforts to transfer newly constructed science knowledge and 'designerly' skills (Baynes, 1994) to the solution of new real-world design problems in an extra-classroom setting? (2) Do DBS curricula support students' efforts to construct new scientific knowledge? (3) Do DBS curricula support students' efforts to develop 'designerly' problem-solving skills? Ninety-two students attending a public high school serving a working class community participated in the consecutive enactments of three different DBS units over one school year. The analysis of pre- and posttests and of artifacts created by the students demonstrated that substantial knowledge was constructed during each of the enactments, with the tests leading to effect sizes of 2.1 on the first unit, 1.9 on the second, and 2.7 on the third. After each enactment the students solved a new design problem as a transfer task. The transfer tasks were unsequestered, unsupported by the teacher, lasted three days, were done in the school's library, required new learning, and were solved in groups of four. In order to generate an individual measure of transfer, the students responded to an individual post-transfer written test after each transfer task was completed, that assessed their understanding and recollection of the solution their group submitted. For all three units there was a stronger correlation between the individual transfer scores and posttests scores than with pretest scores, indicating that the knowledge and skills that were constructed during the enactments supported the solution of the transfer tasks. The correlations with the posttests increased from one enactment to the next, demonstrating that the students' transfer performance improved as they gained more experience in DBS classrooms. Potential threats to the study's internal validity that were identified and discussed were improved teacher proficiency, the nature of the transfer tasks, the difficulty of the science content covered by the units, the similarity between the units and the transfer tasks, and the similarity between the transfer tasks. This dissertation demonstrates that: (a) appropriate learning environments can foster transfer, (b) transfer performance can improve over time, and (c) that it may be necessary to rethink and redefine the procedures for identifying and assessing real-world transfer.
The Effects of Transferred Vocabulary Knowledge on the Development of L2 Reading Proficiency.
ERIC Educational Resources Information Center
Koda, Keiko
1989-01-01
Examination of the effects of transferred vocabulary knowledge on college students' (N=24) acquisition of Japanese linguistic knowledge, verbal processing skills, and reading comprehension indicated that vocabulary knowledge was most highly correlated with reading comprehension. This initial advantage magnified its effects over time as task…
Knowledge and Policy: Research and Knowledge Transfer
ERIC Educational Resources Information Center
Ozga, Jenny
2007-01-01
Knowledge transfer (KT) is the emergent "third sector" of higher education activity--alongside research and teaching. Its commercialization origins are evidenced in its concerns to extract maximum value from research, and in the policy push to make research-based knowledge trapped in disciplinary silos more responsive to the growing…
Exploring hurdles to transfer : student experiences of applying knowledge across disciplines
NASA Astrophysics Data System (ADS)
Lappalainen, Jouni; Rosqvist, Juho
2015-04-01
This paper explores the ways students perceive the transfer of learned knowledge to new situations - often a surprisingly difficult prospect. The novel aspect compared to the traditional transfer studies is that the learning phase is not a part of the experiment itself. The intention was only to activate acquired knowledge relevant to the transfer target using a short primer immediately prior to the situation where the knowledge was to be applied. Eight volunteer students from either mathematics or computer science curricula were given a task of designing an adder circuit using logic gates: a new context in which to apply knowledge of binary arithmetic and Boolean algebra. The results of a phenomenographic classification of the views presented by the students in their post-experiment interviews are reported. The degree to which the students were conscious of the acquired knowledge they employed and how they applied it in a new context emerged as the differentiating factors.
Soldati, Gustavo Taboada; Hanazaki, Natália; Crivos, Marta; Albuquerque, Ulysses Paulino
2015-01-01
Greater socio-environmental instability favors the individual production of knowledge because innovations are adapted to new circumstances. Furthermore, instability stimulates the horizontal transmission of knowledge because this mechanism disseminates adapted information. This study investigates the following hypothesis: Greater socio-environmental instability favors the production of knowledge (innovation) to adapt to new situations, and socio-environmental instability stimulates the horizontal transmission of knowledge, which is a mechanism that diffuses adapted information. In addition, the present study describes “how”, “when”, “from whom” and the “stimulus/context”, in which knowledge regarding medicinal plants is gained or transferred. Data were collected through semi-structured interviews from three groups that represented different levels of socio-environmental instability. Socio-environmental instability did not favor individual knowledge production or any cultural transmission modes, including vertical to horizontal, despite increasing the frequency of horizontal pathways. Vertical transmission was the most important knowledge transmission strategy in all of the groups in which mothers were the most common models (knowledge sources). Significantly, childhood was the most important learning stage, although learning also occurred throughout life. Direct teaching using language was notable as a knowledge transmission strategy. Illness was the main stimulus that triggered local learning. Learning modes about medicinal plants were influenced by the knowledge itself, particularly the dynamic uses of therapeutic resources. PMID:25992578
Rényi information flow in the Ising model with single-spin dynamics.
Deng, Zehui; Wu, Jinshan; Guo, Wenan
2014-12-01
The n-index Rényi mutual information and transfer entropies for the two-dimensional kinetic Ising model with arbitrary single-spin dynamics in the thermodynamic limit are derived as functions of ensemble averages of observables and spin-flip probabilities. Cluster Monte Carlo algorithms with different dynamics from the single-spin dynamics are thus applicable to estimate the transfer entropies. By means of Monte Carlo simulations with the Wolff algorithm, we calculate the information flows in the Ising model with the Metropolis dynamics and the Glauber dynamics, respectively. We find that not only the global Rényi transfer entropy, but also the pairwise Rényi transfer entropy, peaks in the disorder phase.
Patent citation network in nanotechnology (1976-2004)
NASA Astrophysics Data System (ADS)
Li, Xin; Chen, Hsinchun; Huang, Zan; Roco, Mihail C.
2007-06-01
The patent citation networks are described using critical node, core network, and network topological analysis. The main objective is understanding of the knowledge transfer processes between technical fields, institutions and countries. This includes identifying key influential players and subfields, the knowledge transfer patterns among them, and the overall knowledge transfer efficiency. The proposed framework is applied to the field of nanoscale science and engineering (NSE), including the citation networks of patent documents, submitting institutions, technology fields, and countries. The NSE patents were identified by keywords "full-text" searching of patents at the United States Patent and Trademark Office (USPTO). The analysis shows that the United States is the most important citation center in NSE research. The institution citation network illustrates a more efficient knowledge transfer between institutions than a random network. The country citation network displays a knowledge transfer capability as efficient as a random network. The technology field citation network and the patent document citation network exhibit a␣less efficient knowledge diffusion capability than a random network. All four citation networks show a tendency to form local citation clusters.
Active Prior Tactile Knowledge Transfer for Learning Tactual Properties of New Objects
Feng, Di
2018-01-01
Reusing the tactile knowledge of some previously-explored objects (prior objects) helps us to easily recognize the tactual properties of new objects. In this paper, we enable a robotic arm equipped with multi-modal artificial skin, like humans, to actively transfer the prior tactile exploratory action experiences when it learns the detailed physical properties of new objects. These experiences, or prior tactile knowledge, are built by the feature observations that the robot perceives from multiple sensory modalities, when it applies the pressing, sliding, and static contact movements on objects with different action parameters. We call our method Active Prior Tactile Knowledge Transfer (APTKT), and systematically evaluated its performance by several experiments. Results show that the robot improved the discrimination accuracy by around 10% when it used only one training sample with the feature observations of prior objects. By further incorporating the predictions from the observation models of prior objects as auxiliary features, our method improved the discrimination accuracy by over 20%. The results also show that the proposed method is robust against transferring irrelevant prior tactile knowledge (negative knowledge transfer). PMID:29466300
Multiscale Modeling of Multiphase Fluid Flow
2016-08-01
the disparate time and length scales involved in modeling fluid flow and heat transfer. Molecular dynamics simulations were carried out to provide a...fluid dynamics methods were used to investigate the heat transfer process in open-cell micro-foam with phase change material; enhancement of natural...Computational fluid dynamics, Heat transfer, Phase change material in Micro-foam, Molecular Dynamics, Multiphase flow, Multiscale modeling, Natural
A Qualitative Study on Knowledge Transfer among Members of the United States Intelligence Community
ERIC Educational Resources Information Center
Keshavarz-Nia, Navid R.
2011-01-01
This study sought to examine the relationship between social interaction and tacit knowledge transfer, as a dyadic exchange of critical knowledge between a Subject Matter Expert (SME) and a Knowledge Recipient (KR). Knowledge was defined as information and know-how, not merely as organized data or a system, but an active social process that was…
Key characteristics of knowledge transfer and exchange in healthcare: integrative literature review.
Pentland, Duncan; Forsyth, Kirsty; Maciver, Donald; Walsh, Mike; Murray, Richard; Irvine, Linda; Sikora, Simon
2011-07-01
This paper presents the results of a review of literature relating to knowledge transfer and exchange in healthcare. Treatment, planning and policy decisions in contemporary nursing and healthcare should be based on sound evidence wherever possible, but research knowledge remains generally underused. Knowledge transfer and exchange initiatives aim to facilitate the accessibility, application and production of evidence and may provide solutions to this challenge. This review was conducted to help inform the design and implementation of knowledge transfer and exchange activities for a large healthcare organization. Databases: ASSIA, Business Source Premier, CINAHL, PsychInfo, Medline and the Cochrane Database of Systematic Reviews. An integrative literature review was carried out including an extensive literature search. English language systematic reviews, literature reviews, primary quantitative and qualitative papers and grey literature of high relevance evaluating, describing or discussing knowledge transfer or exchange activities in healthcare were included for review (January 1990-September 2009). Thirty-three papers were reviewed (four systematic reviews, nine literature reviews, one environmental scan, nine empirical studies and ten case studies). Robust research into knowledge transfer and exchange in healthcare is limited. Analysis of a wide range of evidence indicates a number of commonly featured characteristics but further evaluation of these activities would benefit their application in facilitating evidence-based practice in nursing. © 2011 The Authors. Journal of Advanced Nursing © 2011 Blackwell Publishing Ltd.
Consulting as a Strategy for Knowledge Transfer
Jacobson, Nora; Butterill, Dale; Goering, Paula
2005-01-01
Academic researchers who work on health policy and health services are expected to transfer knowledge to decision makers. Decision makers often do not, however, regard academics’ traditional ways of doing research and disseminating their findings as relevant or useful. This article argues that consulting can be a strategy for transferring knowledge between researchers and decision makers and is effective at promoting the “enlightenment” and “interactive” models of knowledge use. Based on three case studies, it develops a model of knowledge transfer–focused consulting that consists of six stages and four types of work. Finally, the article explores how knowledge is generated in consulting and identifies several classes of factors facilitating its use by decision makers. PMID:15960773
Criteria and Indicators as Negotiated Knowledge and the Challenge of Transfer
ERIC Educational Resources Information Center
Bormann, Inka
2007-01-01
This paper aims to understand the effects on which criteria and indicators for (education for) sustainable development [(E)SD] are based in terms of knowledge transfer. Therefore, (E)SD criteria and indicators in general are regarded as negotiated and established knowledge, incorporating expectations. As such, this knowledge can be spread…
ERIC Educational Resources Information Center
Schonborn, Konrad J.; Bogeholz, Susanne
2009-01-01
Recent curriculum reform promotes core competencies such as desired "content knowledge" and "communication" for meaningful learning in biology. Understanding in biology is demonstrated when pupils can apply acquired knowledge to new tasks. This process requires the transfer of knowledge and the subordinate process of translation across external…
Davies, Alicia; Wong, Carol A; Laschinger, Heather
2011-07-01
The purpose of this study was to test Kanter's theory by examining relationships among structural empowerment, leader-member exchange (LMX) quality and nurses' participation in personal knowledge transfer activities. Despite the current emphasis on evidence-based practice in health care, research suggests that implementation of research findings in everyday clinical practice is unsystematic at best with mixed outcomes. This study was a secondary analysis of data collected using a non-experimental, predictive mailed survey design. A random sample of 400 registered nurses who worked in urban tertiary care hospitals in Ontario yielded a final sample of 234 for a 58.5% response rate. Hierarchical multiple linear regression analysis revealed that the combination of LMX and structural empowerment accounted for 9.1% of the variance in personal knowledge transfer but only total empowerment was a significant independent predictor of knowledge transfer (β=0.291, t=4.012, P<0.001). Consistent with Kanter's Theory, higher levels of empowerment and leader-member exchange quality resulted in increased participation in personal knowledge transfer in practice. The results reinforce the pivotal role of nurse managers in supporting empowering work environments that are conducive to transfer of knowledge in practice to provide evidence-based care. © 2011 The Authors. Journal compilation © 2011 Blackwell Publishing Ltd.
Nanoscale inhomogeneity and photoacid generation dynamics in extreme ultraviolet resist materials
NASA Astrophysics Data System (ADS)
Wu, Ping-Jui; Wang, Yu-Fu; Chen, Wei-Chi; Wang, Chien-Wei; Cheng, Joy; Chang, Vencent; Chang, Ching-Yu; Lin, John; Cheng, Yuan-Chung
2018-03-01
The development of extreme ultraviolet (EUV) lithography towards the 22 nm node and beyond depends critically on the availability of resist materials that meet stringent control requirements in resolution, line edge roughness, and sensitivity. However, the molecular mechanisms that govern the structure-function relationships in current EUV resist systems are not well understood. In particular, the nanoscale structures of the polymer base and the distributions of photoacid generators (PAGs) should play a critical roles in the performance of a resist system, yet currently available models for photochemical reactions in EUV resist systems are exclusively based on homogeneous bulk models that ignore molecular-level details of solid resist films. In this work, we investigate how microscopic molecular organizations in EUV resist affect photoacid generations in a bottom-up approach that describes structure-dependent electron-transfer dynamics in a solid film model. To this end, molecular dynamics simulations and stimulated annealing are used to obtain structures of a large simulation box containing poly(4-hydroxystyrene) (PHS) base polymers and triphenylsulfonium based PAGs. Our calculations reveal that ion-pair interactions govern the microscopic distributions of the polymer base and PAG molecules, resulting in a highly inhomogeneous system with nonuniform nanoscale chemical domains. Furthermore, the theoretical structures were used in combination of quantum chemical calculations and the Marcus theory to evaluate electron transfer rates between molecular sites, and then kinetic Monte Carlo simulations were carried out to model electron transfer dynamics with molecular structure details taken into consideration. As a result, the portion of thermalized electrons that are absorbed by the PAGs and the nanoscale spatial distribution of generated acids can be estimated. Our data reveal that the nanoscale inhomogeneous distributions of base polymers and PAGs strongly affect the electron transfer and the performance of the resist system. The implications to the performances of EUV resists and key engineering requirements for improved resist systems will also be discussed in this work. Our results shed light on the fundamental structure dependence of photoacid generation and the control of the nanoscale structures as well as base polymer-PAG interactions in EVU resist systems, and we expect these knowledge will be useful for the future development of improved EUV resist systems.
A new computational method for the detection of horizontal gene transfer events.
Tsirigos, Aristotelis; Rigoutsos, Isidore
2005-01-01
In recent years, the increase in the amounts of available genomic data has made it easier to appreciate the extent by which organisms increase their genetic diversity through horizontally transferred genetic material. Such transfers have the potential to give rise to extremely dynamic genomes where a significant proportion of their coding DNA has been contributed by external sources. Because of the impact of these horizontal transfers on the ecological and pathogenic character of the recipient organisms, methods are continuously sought that are able to computationally determine which of the genes of a given genome are products of transfer events. In this paper, we introduce and discuss a novel computational method for identifying horizontal transfers that relies on a gene's nucleotide composition and obviates the need for knowledge of codon boundaries. In addition to being applicable to individual genes, the method can be easily extended to the case of clusters of horizontally transferred genes. With the help of an extensive and carefully designed set of experiments on 123 archaeal and bacterial genomes, we demonstrate that the new method exhibits significant improvement in sensitivity when compared to previously published approaches. In fact, it achieves an average relative improvement across genomes of between 11 and 41% compared to the Codon Adaptation Index method in distinguishing native from foreign genes. Our method's horizontal gene transfer predictions for 123 microbial genomes are available online at http://cbcsrv.watson.ibm.com/HGT/.
1991-01-01
Understanding how STI is commun- aerospace knowledge- efficient and effective transfer and cated in the process of technolgical diffusion of knowledge within...However, as important international levels, diffusion of knowledge in the aeros- as the transfer and utilisation of STI is to which will help to pace...diffused is neces- diffusion of knowledge . Phase 3 ex- formation specialist). Phase 2 examined sary to successfully manage technolog- plores the information
Chang, Hang; Han, Ju; Zhong, Cheng; Snijders, Antoine M.; Mao, Jian-Hua
2017-01-01
The capabilities of (I) learning transferable knowledge across domains; and (II) fine-tuning the pre-learned base knowledge towards tasks with considerably smaller data scale are extremely important. Many of the existing transfer learning techniques are supervised approaches, among which deep learning has the demonstrated power of learning domain transferrable knowledge with large scale network trained on massive amounts of labeled data. However, in many biomedical tasks, both the data and the corresponding label can be very limited, where the unsupervised transfer learning capability is urgently needed. In this paper, we proposed a novel multi-scale convolutional sparse coding (MSCSC) method, that (I) automatically learns filter banks at different scales in a joint fashion with enforced scale-specificity of learned patterns; and (II) provides an unsupervised solution for learning transferable base knowledge and fine-tuning it towards target tasks. Extensive experimental evaluation of MSCSC demonstrates the effectiveness of the proposed MSCSC in both regular and transfer learning tasks in various biomedical domains. PMID:28129148
Forests and Their Canopies: Achievements and Horizons in Canopy Science.
Nakamura, Akihiro; Kitching, Roger L; Cao, Min; Creedy, Thomas J; Fayle, Tom M; Freiberg, Martin; Hewitt, C N; Itioka, Takao; Koh, Lian Pin; Ma, Keping; Malhi, Yadvinder; Mitchell, Andrew; Novotny, Vojtech; Ozanne, Claire M P; Song, Liang; Wang, Han; Ashton, Louise A
2017-06-01
Forest canopies are dynamic interfaces between organisms and atmosphere, providing buffered microclimates and complex microhabitats. Canopies form vertically stratified ecosystems interconnected with other strata. Some forest biodiversity patterns and food webs have been documented and measurements of ecophysiology and biogeochemical cycling have allowed analyses of large-scale transfer of CO 2 , water, and trace gases between forests and the atmosphere. However, many knowledge gaps remain. With global research networks and databases, and new technologies and infrastructure, we envisage rapid advances in our understanding of the mechanisms that drive the spatial and temporal dynamics of forests and their canopies. Such understanding is vital for the successful management and conservation of global forests and the ecosystem services they provide to the world. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
Modeling of dislocation dynamics in germanium Czochralski growth
NASA Astrophysics Data System (ADS)
Artemyev, V. V.; Smirnov, A. D.; Kalaev, V. V.; Mamedov, V. M.; Sidko, A. P.; Podkopaev, O. I.; Kravtsova, E. D.; Shimansky, A. F.
2017-06-01
Obtaining very high-purity germanium crystals with low dislocation density is a practically difficult problem, which requires knowledge and experience in growth processes. Dislocation density is one of the most important parameters defining the quality of germanium crystal. In this paper, we have performed experimental study of dislocation density during 4-in. germanium crystal growth using the Czochralski method and comprehensive unsteady modeling of the same crystal growth processes, taking into account global heat transfer, melt flow and melt/crystal interface shape evolution. Thermal stresses in the crystal and their relaxation with generation of dislocations within the Alexander-Haasen model have been calculated simultaneously with crystallization dynamics. Comparison to experimental data showed reasonable agreement for the temperature, interface shape and dislocation density in the crystal between calculation and experiment.
Dynamic Stiffness Transfer Function of an Electromechanical Actuator Using System Identification
NASA Astrophysics Data System (ADS)
Kim, Sang Hwa; Tahk, Min-Jea
2018-04-01
In the aeroelastic analysis of flight vehicles with electromechanical actuators (EMAs), an accurate prediction of flutter requires dynamic stiffness characteristics of the EMA. The dynamic stiffness transfer function of the EMA with brushless direct current (BLDC) motor can be obtained by conducting complicated mathematical calculations of control algorithms and mechanical/electrical nonlinearities using linearization techniques. Thus, system identification approaches using experimental data, as an alternative, have considerable advantages. However, the test setup for system identification is expensive and complex, and experimental procedures for data collection are time-consuming tasks. To obtain the dynamic stiffness transfer function, this paper proposes a linear system identification method that uses information obtained from a reliable dynamic stiffness model with a control algorithm and nonlinearities. The results of this study show that the system identification procedure is compact, and the transfer function is able to describe the dynamic stiffness characteristics of the EMA. In addition, to verify the validity of the system identification method, the simulation results of the dynamic stiffness transfer function and the dynamic stiffness model were compared with the experimental data for various external loads.
"JOB SEEKER"(Job Shadowing for Employee Engagement through Knowledge and Experience Retention).
DOT National Transportation Integrated Search
2016-05-01
The main objective of this study was to explore how to optimally use the particular knowledge : retention/transfer technique of job shadowing as an informal method for knowledge capture and : transfer as well as increasing communication and emp...
Reaction kinetics in open reactors and serial transfers between closed reactors
NASA Astrophysics Data System (ADS)
Blokhuis, Alex; Lacoste, David; Gaspard, Pierre
2018-04-01
Kinetic theory and thermodynamics of reaction networks are extended to the out-of-equilibrium dynamics of continuous-flow stirred tank reactors (CSTR) and serial transfers. On the basis of their stoichiometry matrix, the conservation laws and the cycles of the network are determined for both dynamics. It is shown that the CSTR and serial transfer dynamics are equivalent in the limit where the time interval between the transfers tends to zero proportionally to the ratio of the fractions of fresh to transferred solutions. These results are illustrated with a finite cross-catalytic reaction network and an infinite reaction network describing mass exchange between polymers. Serial transfer dynamics is typically used in molecular evolution experiments in the context of research on the origins of life. The present study is shedding a new light on the role played by serial transfer parameters in these experiments.
ERIC Educational Resources Information Center
Khan, Abdul Azeez; Khader, Sheik Abdul
2014-01-01
E-learning or electronic learning platforms facilitate delivery of the knowledge spectrum to the learning community through information and communication technologies. The transfer of knowledge takes place from experts to learners, and externalization of the knowledge transfer is significant. In the e-learning environment, the learners seek…
E-Learning Barriers and Solutions to Knowledge Management and Transfer
ERIC Educational Resources Information Center
Oye, Nathaniel David; Salleh, Mazleena
2013-01-01
This paper present a systematic overview of barriers and solutions of e-learning in knowledge management (KM) and knowledge transfer (KT) with more focus on organizations. The paper also discusses KT in organizational settings and KT in the field of e-learning. Here, an e-learning initiative shows adaptive solutions to overcome knowledge transfer…
Analysis of a Knowledge-Management-Based Process of Transferring Project Management Skills
ERIC Educational Resources Information Center
Ioi, Toshihiro; Ono, Masakazu; Ishii, Kota; Kato, Kazuhiko
2012-01-01
Purpose: The purpose of this paper is to propose a method for the transfer of knowledge and skills in project management (PM) based on techniques in knowledge management (KM). Design/methodology/approach: The literature contains studies on methods to extract experiential knowledge in PM, but few studies exist that focus on methods to convert…
Martinez, Luis F; Ferreira, Aristides I; Can, Amina B
2016-04-01
Based on Szulanski's knowledge transfer model, this study examined how the communicational, motivational, and sharing of understanding variables influenced knowledge transfer and change processes in small- and medium-sized enterprises, particularly under projects developed by funded programs. The sample comprised 144 entrepreneurs, mostly male (65.3%) and mostly ages 35 to 45 years (40.3%), who filled an online questionnaire measuring the variables of "sharing of understanding," "motivation," "communication encoding competencies," "source credibility," "knowledge transfer," and "organizational change." Data were collected between 2011 and 2012 and measured the relationship between clients and consultants working in a Portuguese small- and medium-sized enterprise-oriented action learning program. To test the hypotheses, structural equation modeling was conducted to identify the antecedents of sharing of understanding, motivational, and communicational variables, which were positively correlated with the knowledge transfer between consultants and clients. This transfer was also positively correlated with organizational change. Overall, the study provides important considerations for practitioners and academicians and establishes new avenues for future studies concerning the issues of consultant-client relationship and the efficacy of Government-funded programs designed to improve performance of small- and medium-sized enterprises. © The Author(s) 2016.
Teacher Candidate Technology Integration: For Student Learning or Instruction?
ERIC Educational Resources Information Center
Clark, Cynthia; Zhang, Shaoan; Strudler, Neal
2015-01-01
Transfer of instructional technology knowledge for student-centered learning by teacher candidates is investigated in this study. Using the transfer of learning theoretical framework, a mixed methods research design was employed to investigate whether secondary teacher candidates were able to transfer the instructional technology knowledge for…
Proceedings: international conference on transfer of forest science knowledge and technology.
Cynthia Miner; Ruth Jacobs; Dennis Dykstra; Becky Bittner
2007-01-01
This proceedings compiles papers presented by extensionists, natural resource specialists, scientists, technology transfer specialists, and others at an international conference that examined knowledge and technology transfer theories, methods, and case studies. Theory topics included adult education, applied science, extension, diffusion of innovations, social...
Extra-team connections for knowledge transfer between staff teams
Ramanadhan, Shoba; Wiecha, Jean L.; Emmons, Karen M.; Gortmaker, Steven L.; Viswanath, Kasisomayajula
2009-01-01
As organizations implement novel health promotion programs across multiple sites, they face great challenges related to knowledge management. Staff social networks may be a useful medium for transferring program-related knowledge in multi-site implementation efforts. To study this potential, we focused on the role of extra-team connections (ties between staff members based in different site teams) as potential channels for knowledge sharing. Data come from a cross-sectional study of afterschool childcare staff implementing a health promotion program at 20 urban sites of the Young Men's Christian Association of Greater Boston. We conducted a sociometric social network analysis and attempted a census of 91 program staff members. We surveyed 80 individuals, and included 73 coordinators and general staff, who lead and support implementation, respectively, in this study. A multiple linear regression model demonstrated a positive relationship between extra-team connections (β = 3.41, P < 0.0001) and skill receipt, a measure of knowledge transfer. We also found that intra-team connections (within-team ties between staff members) were also positively related to skill receipt. Connections between teams appear to support knowledge transfer in this network, but likely require greater active facilitation, perhaps via organizational changes. Further research on extra-team connections and knowledge transfer in low-resource, high turnover environments is needed. PMID:19528313
Schuelke, Matthew J; Day, Eric Anthony; McEntire, Lauren E; Boatman, Jazmine Espejo; Wang, Xiaoqian; Kowollik, Vanessa; Boatman, Paul R
2009-07-01
The authors examined the relative criterion-related validity of knowledge structure coherence and two accuracy-based indices (closeness and correlation) as well as the utility of using a combination of knowledge structure indices in the prediction of skill acquisition and transfer. Findings from an aggregation of 5 independent samples (N = 958) whose participants underwent training on a complex computer simulation indicated that coherence and the accuracy-based indices yielded comparable zero-order predictive validities. Support for the incremental validity of using a combination of indices was mixed; the most, albeit small, gain came in pairing coherence and closeness when predicting transfer. After controlling for baseline skill, general mental ability, and declarative knowledge, only coherence explained a statistically significant amount of unique variance in transfer. Overall, the results suggested that the different indices largely overlap in their representation of knowledge organization, but that coherence better reflects adaptable aspects of knowledge organization important to skill transfer.
Discourses of anxiety and transference in nursing practice: the subject of knowledge.
Evans, Alicia M; Pereira, David A; Parker, Judith M
2009-09-01
The nurses' relationship to knowledge has been theorised in a variety of different ways, not the least being in relation to medical dominance. In this study, the authors report on one of the findings of a case study into nurses' anxiety informed by psychoanalytic theory. They argue that the nurse's subjection to the knowledge of the other health professional, inclusive of the doctor, can be a transference arising in the context of anxiety for the nurse. Grasped by anxiety, the nurse finds their own knowledge insufficient and in this moment can operate a transference to their non-nursing colleague, who obligingly, responds. This transference is not present in the change-of-shift handover report though, when the other's knowledge is suspect, even open to derision. Thus, this reference to the knowledge of the other is not consistently present in nursing and can be seen to be just one way that nurses organise themselves in relation to anxiety. Therefore, those wanting to break down the medical dominance of the nursing profession might consider other ways nurses might organise themselves in relation to anxiety, so that the political dominance of the other is not reinforced via transference to that other.
Knowledge Translation Tools are Emerging to Move Neck Pain Research into Practice.
Macdermid, Joy C; Miller, Jordan; Gross, Anita R
2013-01-01
Development or synthesis of the best clinical research is in itself insufficient to change practice. Knowledge translation (KT) is an emerging field focused on moving knowledge into practice, which is a non-linear, dynamic process that involves knowledge synthesis, transfer, adoption, implementation, and sustained use. Successful implementation requires using KT strategies based on theory, evidence, and best practice, including tools and processes that engage knowledge developers and knowledge users. Tools can provide instrumental help in implementing evidence. A variety of theoretical frameworks underlie KT and provide guidance on how tools should be developed or implemented. A taxonomy that outlines different purposes for engaging in KT and target audiences can also be useful in developing or implementing tools. Theoretical frameworks that underlie KT typically take different perspectives on KT with differential focus on the characteristics of the knowledge, knowledge users, context/environment, or the cognitive and social processes that are involved in change. Knowledge users include consumers, clinicians, and policymakers. A variety of KT tools have supporting evidence, including: clinical practice guidelines, patient decision aids, and evidence summaries or toolkits. Exemplars are provided of two KT tools to implement best practice in management of neck pain-a clinician implementation guide (toolkit) and a patient decision aid. KT frameworks, taxonomies, clinical expertise, and evidence must be integrated to develop clinical tools that implement best evidence in the management of neck pain.
Visualizing the dynamic structure of the plant photosynthetic membrane.
Ruban, Alexander V; Johnson, Matthew P
2015-11-03
The chloroplast thylakoid membrane is the site for the initial steps of photosynthesis that convert solar energy into chemical energy, ultimately powering almost all life on earth. The heterogeneous distribution of protein complexes within the membrane gives rise to an intricate three-dimensional structure that is nonetheless extremely dynamic on a timescale of seconds to minutes. These dynamics form the basis for the regulation of photosynthesis, and therefore the adaptability of plants to different environments. High-resolution microscopy has in recent years begun to provide new insights into the structural dynamics underlying a number of regulatory processes such as membrane stacking, photosystem II repair, photoprotective energy dissipation, state transitions and alternative electron transfer. Here we provide an overview of the essentials of thylakoid membrane structure in plants, and consider how recent advances, using a range of microscopies, have substantially increased our knowledge of the thylakoid dynamic structure. We discuss both the successes and limitations of the currently available techniques and highlight newly emerging microscopic methods that promise to move the field beyond the current 'static' view of membrane organization based on frozen snapshots to a 'live' view of functional membranes imaged under native aqueous conditions at ambient temperature and responding dynamically to external stimuli.
Traceable calibration and demonstration of a portable dynamic force transfer standard
NASA Astrophysics Data System (ADS)
Vlajic, Nicholas; Chijioke, Ako
2017-08-01
In general, the dynamic sensitivity of a force transducer depends upon the mechanical system in which it is used. This dependence serves as motivation to develop a dynamic force transfer standard, which can be used to calibrate an application transducer in situ. In this work, we SI-traceably calibrate a hand-held force transducer, namely an impact hammer, by using a mass suspended from a thin line which is cut to produce a known dynamic force in the form of a step function. We show that this instrument is a promising candidate as a transfer standard, since its dynamic response has small variance between different users. This calibrated transfer standard is then used to calibrate a secondary force transducer in an example application setting. The combined standard uncertainty (k = 2) in the calibration of the transfer standard was determined to be 2.1% or less, up to a bandwidth of 5 kHz. The combined standard uncertainty (k = 2) in the performed transfer calibration was less than 4%, up to 3 kHz. An advantage of the transfer calibration framework presented here, is that the transfer standard can be used to transfer SI-traceable calibrations without the use of any SI-traceable voltage metrology instrumentation.
Taylor, Georgette
2014-02-01
This article contributes to a growing body of research on the dissemination, dispersion or diffusion of scientific knowledge via pedagogical networks. By examining students' handwritten lecture notes, I compare the eighteenth-century chemistry lectures given by William Cullen (1710-1790) at Glasgow and Edinburgh Universities with those of his one-time student George Fordyce (1736-1802), in London, at first privately and then as part of the medical education of physicians at St. Thomas's Hospital. Part I examines the broad structure of Cullen's and Fordyce's courses, comparing both course content and pedagogical approaches to ask how far knowledge flowed directly 'downstream,' and the extent to which it was transformed, translated or transmuted in the process of transmission. Part II (forthcoming) will approach the affinity theories of Cullen and Fordyce in greater depth, revealing the dynamics of knowledge transfer. The results shed light on the transmission of knowledge and skills between master and student, and reflect on whether Fordyce can be better described as Cullen's pedagogical progeny, or less straightforwardly as a tactical translator.
Continuing education at the cutting edge: promoting transformative knowledge translation.
McWilliam, Carol L
2007-01-01
As the evidence-based practice movement gains momentum, continuing education practitioners increasingly confront the challenge of developing and conducting opportunities for achieving research uptake. Recent thinking invites new approaches to continuing education for health professionals, with due consideration of what knowledge merits uptake by practitioners, who should play what role in the knowledge transfer process, and what educational approach should be used. This article presents an innovative theory-based strategy that encompasses this new perspective. Through a facilitated experience of perspective transformation, clinicians are engaged in an on-the-job process of developing a deeply felt interest in research findings relevant to everyday practice, as well as ownership of that knowledge and its application. The strategy becomes a sustainable, integrated part of clinical practice, fitting naturally within its dynamic, unique environment, context, and climate and overcoming the barrier of time. Clinician experience of a top-down push toward prescribed practice change is avoided. With an expanded role encompassing facilitation of active learning partnerships for practice change, the continuing educator fosters a learning organization culture across the institution. The resultant role changes and leadership and accountability issues are elaborated.
The Nazaré Wave: a trigger for learning
NASA Astrophysics Data System (ADS)
Carapuço, M. M.; Cunha, A.; Taborda, R.; Andrade, C.; Maurício, C.
2016-02-01
Ocean management faces relevant sustainability challenges. It is consensual that a wiser governance of the oceans can only be achieved by the involvement of all key-players. In this scope scientists, as knowledge generators, have a vital role in ocean governance. Scientists are therefore called to share their knowledge outside the scientific community. This effort, framed under the Responsible Research and Innovation approach, will contribute to a more informed society, which in turn will be able to make better decisions. However, communicating science is a challenging task as is often necessary to inspire the audience and assure their receptivity, which may not be tuned to scientific contents. The present work focuses on the importance of the use of communication triggers in scientific knowledge transfer in ocean sciences. In this work the Nazaré wave - the highest wave ever surfed - was used as the communication trigger as it is a very popular subject with the media and is given great media coverage. Results show that the use of this subject can be an excellent trigger for the transfer of scientific knowledge on basic wave dynamics to the students. Additionally to the theme itself, it was found that short scientific animation videos voiced-over by students performed very well as the communication channel. The scripts used were written by scientists and commented by the students, previously to recording, assuring that the adequate language was used, and that the essential principles and fundamental concepts of waves reach the audience. Results of using the Nazaré´ wave as a communication trigger have been extremely positive and resulted in a well-succeeded engagement platform.
Compositional clustering in task structure learning
Frank, Michael J.
2018-01-01
Humans are remarkably adept at generalizing knowledge between experiences in a way that can be difficult for computers. Often, this entails generalizing constituent pieces of experiences that do not fully overlap, but nonetheless share useful similarities with, previously acquired knowledge. However, it is often unclear how knowledge gained in one context should generalize to another. Previous computational models and data suggest that rather than learning about each individual context, humans build latent abstract structures and learn to link these structures to arbitrary contexts, facilitating generalization. In these models, task structures that are more popular across contexts are more likely to be revisited in new contexts. However, these models can only re-use policies as a whole and are unable to transfer knowledge about the transition structure of the environment even if only the goal has changed (or vice-versa). This contrasts with ecological settings, where some aspects of task structure, such as the transition function, will be shared between context separately from other aspects, such as the reward function. Here, we develop a novel non-parametric Bayesian agent that forms independent latent clusters for transition and reward functions, affording separable transfer of their constituent parts across contexts. We show that the relative performance of this agent compared to an agent that jointly clusters reward and transition functions depends environmental task statistics: the mutual information between transition and reward functions and the stochasticity of the observations. We formalize our analysis through an information theoretic account of the priors, and propose a meta learning agent that dynamically arbitrates between strategies across task domains to optimize a statistical tradeoff. PMID:29672581
Technology transfer for women entrepreneurs: issues for consideration.
Everts, S I
1998-01-01
This article discusses the effectiveness of technology transfers to women entrepreneurs in developing countries. Most women's enterprises share common characteristics: very small businesses, employment of women owners and maybe some family members, limited working capital, low profit margins, and flexible or part-time work. Many enterprises do not plan for growth. Women tend to diversify and use risk-avoidance strategies. Support for women's enterprises ignores the characteristics of women's enterprises. Support mechanisms could be offered that would perfect risk-spreading strategies and dynamic enterprise management through other means than growth. Many initiatives, since the 1970s, have transferred technologies to women. Technologies were applied to only a few domains and were viewed as appropriate based on their small size, low level of complexity, low cost, and environmental friendliness. Technology transfers may not be viewed by beneficiaries as the appropriate answer to needs. The bottleneck in transfers to women is not in the development of prototypes, but in the dissemination of technology that is sustainable, appropriate, and accessible. Key features for determining appropriateness include baseline studies, consumer linkages, and a repetitive process. Institutional factors may limit appropriateness. There is a need for long-term outputs, better links with users, training in use of the technology, grouping of women into larger units, and technology availability in quantities large enough to meet demand. Guidelines need to be developed that include appropriate content and training that ensures transfer of knowledge to practice.
The direction of bilateral transfer depends on the performance parameter.
Pan, Zhujun; van Gemmert, Arend W A
2013-10-01
To acquire a more comprehensive understanding of the learning benefits associated with bilateral transfer and to gain knowledge of possible mechanisms behind bilateral transfer, we investigated the transfer direction of several parameters which are assumed to represent important features of movement control in a visuo-motor task. During the study, participants learned a multidirectional point-to-point drawing task in which the visual feedback was rotated 45° and the gain was increased. Performance changes of the untrained hand in movement time, trajectory length, normalized jerk, initial direction error, ratio of the primary sub-movement time to the total movement time, and the accuracy of the aiming movement after the primary sub-movement were investigated as indices of learning from bilateral transfer. The results showed that performance parameters related to the initial production of the movement, such as the initial direction, ratio of primary sub-movement to the total movement time, and movement accuracy after the primary sub-movement, only transferred to the non-dominant, while hand performance variables related to the overall outcome, such as movement duration, movement smoothness, and trajectory length, transferred in both directions. The findings of the current study support the basic principle of the "dynamic dominance model" because it is suggested that overall improvements in the non-dominant system are controlled by trajectory parameters in visuo-motor tasks, which resulted in transference of the afore mentioned production parameters to rather occur to the non-dominant hand as opposed to transference to the dominant hand. Published by Elsevier B.V.
Sticky knowledge: A possible model for investigating implementation in healthcare contexts
Elwyn, Glyn; Taubert, Mark; Kowalczuk, Jenny
2007-01-01
Background In health care, a well recognized gap exists between what we know should be done based on accumulated evidence and what we actually do in practice. A body of empirical literature shows organizations, like individuals, are difficult to change. In the business literature, knowledge management and transfer has become an established area of theory and practice, whilst in healthcare it is only starting to establish a firm footing. Knowledge has become a business resource, and knowledge management theorists and practitioners have examined how knowledge moves in organisations, how it is shared, and how the return on knowledge capital can be maximised to create competitive advantage. New models are being considered, and we wanted to explore the applicability of one of these conceptual models to the implementation of evidence-based practice in healthcare systems. Methods The application of a conceptual model called sticky knowledge, based on an integration of communication theory and knowledge transfer milestones, into a scenario of attempting knowledge transfer in primary care. Results We describe Szulanski's model, the empirical work he conducted, and illustrate its potential applicability with a hypothetical healthcare example based on improving palliative care services. We follow a doctor through two different posts and analyse aspects of knowledge transfer in different primary care settings. The factors included in the sticky knowledge model include: causal ambiguity, unproven knowledge, motivation of source, credibility of source, recipient motivation, recipient absorptive capacity, recipient retentive capacity, barren organisational context, and arduous relationship between source and recipient. We found that we could apply all these factors to the difficulty of implementing new knowledge into practice in primary care settings. Discussion Szulanski argues that knowledge factors play a greater role in the success or failure of a knowledge transfer than has been suspected, and we consider that this conjecture requires further empirical work in healthcare settings. PMID:18096040
ERIC Educational Resources Information Center
Hope, Alex
2016-01-01
Purpose: The purpose of this paper is to examine the use of knowledge transfer partnership (KTP)as a means for universities to generate and exchange knowledge to foster sustainable cities and societies. Design/methodology/approach: This paper reports on a series of separate yet interrelated KTPs between a university and the local authority in the…
Writing a bachelor thesis generates transferable knowledge and skills useable in nursing practice.
Lundgren, Solveig M; Robertsson, Barbro
2013-11-01
Generic skills or transferable skills have been discussed in terms of whether or not skills learned in one context can be transferred into another context. The current study was aimed to explore nurses' self-perceptions of the knowledge and skills they had obtained while writing a Bachelor's thesis in nursing education, their experience of the extent of transfer and utilization in their current work. Responding nurses (N=42) had all worked from 1 to 1.5 years after their final examination and had completed a questionnaire that was structured with open-ended questions. Only five nurses reported that they were unable to use any of the knowledge and skills they had obtained from writing a thesis. A majority of the nurses (37/42) could give many examples of the practical application of the skills and knowledge they had obtained. Our findings indicate that writing a thesis as part of an undergraduate degree program plays a major role in the acquisition and development of knowledge and skills which can subsequently be transferred into and utilized in nursing practice. Copyright © 2012 Elsevier Ltd. All rights reserved.
Gharasoo, Mehdi; Centler, Florian; Van Cappellen, Philippe; Wick, Lukas Y; Thullner, Martin
2015-05-05
Microbial degradation is an important process in many environments controlling for instance the cycling of nutrients or the biodegradation of contaminants. At high substrate concentrations toxic effects may inhibit the degradation process. Bioavailability limitations of a degradable substrate can therefore either improve the overall dynamics of degradation by softening the contaminant toxicity effects to microorganisms, or slow down the biodegradation by reducing the microbial access to the substrate. Many studies on biodegradation kinetics of a self-inhibitive substrate have mainly focused on physiological responses of the bacteria to substrate concentration levels without considering the substrate bioavailability limitations rising from different geophysical and geochemical dynamics at pore-scale. In this regard, the role of bioavailability effects on the kinetics of self-inhibiting substrates is poorly understood. In this study, we theoretically analyze this role and assess the interactions between self-inhibition and mass transfer-limitations using analytical/numerical solutions, and show the findings practical relevance for a simple model scenario. Although individually self-inhibition and mass-transfer limitations negatively impact biodegradation, their combined effect may enhance biodegradation rates above a concentration threshold. To our knowledge, this is the first theoretical study describing the cumulative effects of the two mechanisms together.
Novo, Leonardo; Chakraborty, Shantanav; Mohseni, Masoud; Neven, Hartmut; Omar, Yasser
2015-01-01
Continuous time quantum walks provide an important framework for designing new algorithms and modelling quantum transport and state transfer problems. Often, the graph representing the structure of a problem contains certain symmetries that confine the dynamics to a smaller subspace of the full Hilbert space. In this work, we use invariant subspace methods, that can be computed systematically using the Lanczos algorithm, to obtain the reduced set of states that encompass the dynamics of the problem at hand without the specific knowledge of underlying symmetries. First, we apply this method to obtain new instances of graphs where the spatial quantum search algorithm is optimal: complete graphs with broken links and complete bipartite graphs, in particular, the star graph. These examples show that regularity and high-connectivity are not needed to achieve optimal spatial search. We also show that this method considerably simplifies the calculation of quantum transport efficiencies. Furthermore, we observe improved efficiencies by removing a few links from highly symmetric graphs. Finally, we show that this reduction method also allows us to obtain an upper bound for the fidelity of a single qubit transfer on an XY spin network. PMID:26330082
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ji, Pengfei; Zhang, Yuwen, E-mail: zhangyu@missouri.edu; Yang, Mo
The structural, dynamic, and vibrational properties during heat transfer process in Si/Ge superlattices are studied by analyzing the trajectories generated by the ab initio Car-Parrinello molecular dynamics simulation. The radial distribution functions and mean square displacements are calculated and further discussions are made to explain and probe the structural changes relating to the heat transfer phenomenon. Furthermore, the vibrational density of states of the two layers (Si/Ge) are computed and plotted to analyze the contributions of phonons with different frequencies to the heat conduction. Coherent heat conduction of the low frequency phonons is found and their contributions to facilitate heatmore » transfer are confirmed. The Car-Parrinello molecular dynamics simulation outputs in the work show reasonable thermophysical results of the thermal energy transport process and shed light on the potential applications of treating the heat transfer in the superlattices of semiconductor materials from a quantum mechanical molecular dynamics simulation perspective.« less
NASA Astrophysics Data System (ADS)
Ji, Pengfei; Zhang, Yuwen; Yang, Mo
2013-12-01
The structural, dynamic, and vibrational properties during heat transfer process in Si/Ge superlattices are studied by analyzing the trajectories generated by the ab initio Car-Parrinello molecular dynamics simulation. The radial distribution functions and mean square displacements are calculated and further discussions are made to explain and probe the structural changes relating to the heat transfer phenomenon. Furthermore, the vibrational density of states of the two layers (Si/Ge) are computed and plotted to analyze the contributions of phonons with different frequencies to the heat conduction. Coherent heat conduction of the low frequency phonons is found and their contributions to facilitate heat transfer are confirmed. The Car-Parrinello molecular dynamics simulation outputs in the work show reasonable thermophysical results of the thermal energy transport process and shed light on the potential applications of treating the heat transfer in the superlattices of semiconductor materials from a quantum mechanical molecular dynamics simulation perspective.
Organizational Politics, Social Network, and Knowledge Management
NASA Astrophysics Data System (ADS)
Lee, Hyun Jung; Kang, Sora; Lee, Jongwon
This research identifies the social relationship and structure among members as well as organization’s political inclination, through which, it also identifies the current status of knowledge management. The result shows that the socio-technological factors (individual, knowledge and IT factors) affect knowledge transfer and the knowledge transfer influences performance and that the members’ relationship based on the political inclination of the organization has a major moderating effect on the above two relation.
Data-Driven Model Reduction and Transfer Operator Approximation
NASA Astrophysics Data System (ADS)
Klus, Stefan; Nüske, Feliks; Koltai, Péter; Wu, Hao; Kevrekidis, Ioannis; Schütte, Christof; Noé, Frank
2018-06-01
In this review paper, we will present different data-driven dimension reduction techniques for dynamical systems that are based on transfer operator theory as well as methods to approximate transfer operators and their eigenvalues, eigenfunctions, and eigenmodes. The goal is to point out similarities and differences between methods developed independently by the dynamical systems, fluid dynamics, and molecular dynamics communities such as time-lagged independent component analysis, dynamic mode decomposition, and their respective generalizations. As a result, extensions and best practices developed for one particular method can be carried over to other related methods.
ERIC Educational Resources Information Center
Manavopoulos, Konstantin; Tzouriadou, Maria
1998-01-01
Investigated whether preschoolers had acquired event knowledge schemata, and the impact of an inductive reasoning training program on knowledge transfer in story recall tasks. Found that inductive reasoning training led to knowledge transfer in kindergartners but had only minor influence on prekindergartners. (Author/KB)
Extra-team Connections for Knowledge Transfer between Staff Teams
ERIC Educational Resources Information Center
Ramanadhan, Shoba; Wiecha, Jean L.; Emmons, Karen M.; Gortmaker, Steven L.; Viswanath, Kasisomayajula
2009-01-01
As organizations implement novel health promotion programs across multiple sites, they face great challenges related to knowledge management. Staff social networks may be a useful medium for transferring program-related knowledge in multi-site implementation efforts. To study this potential, we focused on the role of extra-team connections (ties…
ERIC Educational Resources Information Center
Hinojosa, Cristelia Zarate
2017-01-01
While knowledge is one of an organization's greatest assets, it remains a challenge to facilitate knowledge transfer between people within an organization. Social influence has been studied in its role of facilitating information diffusion, which is necessary for knowledge transfer to occur. Among this research, tie strength, a quantifiable…
Training and Organizational Effectiveness: Moderating Role of Knowledge Management Process
ERIC Educational Resources Information Center
Rahman, Azmawani Abd; Ng, Siew Imm; Sambasivan, Murali; Wong, Florence
2013-01-01
Purpose: Training alone is not sufficient to enhance organizational effectiveness to a greater level because not all knowledge obtained from the training is properly transferred and applied to the organization. This study aims to investigate whether efforts invested by Malaysian manufacturers in employee training and knowledge transfer affect…
Linnander, Erika; Yuan, Christina T; Ahmed, Shirin; Cherlin, Emily; Talbert-Slagle, Kristina; Curry, Leslie A
2017-01-01
Persistent gaps in the availability of essential medicines have slowed the achievement of global health targets. Despite the supply chain knowledge and expertise that ministries of health might glean from other industries, limited empirical research has examined the process of knowledge transfer from other industries into global public health. We examined a partnership designed to improve the availability of medical supplies in Tanzania by transferring knowledge from The Coca-Cola system to Tanzania's Medical Stores Department (MSD). We conducted a process evaluation including in-depth interviews with 70 participants between July 2011 and May 2014, corresponding to each phase of the partnership, with focus on challenges and strategies to address them, as well as benefits perceived by partners. Partners faced challenges in (1) identifying relevant knowledge to transfer, (2) translating operational solutions from Coca-Cola to MSD, and (3) maintaining momentum between project phases. Strategies to respond to these challenges emerged through real-time problem solving and included (1) leveraging the receptivity of MSD leadership, (2) engaging a boundary spanner to identify knowledge to transfer, (3) promoting local recognition of commonalities across industries, (4) engaging external technical experts to manage translation activities, (5) developing tools with visible benefits for MSD, (6) investing in local relationships, and (7) providing time and space for the partnership model to evolve. Benefits of the partnership perceived by MSD staff included enhanced collaboration and communication, more proactive orientations in managing operations, and greater attention to performance management. Benefits perceived by Coca-Cola staff included strengthened knowledge transfer capability and enhanced job satisfaction. Linking theoretical constructs with practical experiences from the field, we highlight the challenges, emergent strategies, and perceived benefits of a partnership across industry boundaries that may be useful to others seeking to promote the transfer of knowledge to improve global health.
Yuan, Christina T.; Ahmed, Shirin; Cherlin, Emily; Talbert-Slagle, Kristina; Curry, Leslie A.
2017-01-01
Persistent gaps in the availability of essential medicines have slowed the achievement of global health targets. Despite the supply chain knowledge and expertise that ministries of health might glean from other industries, limited empirical research has examined the process of knowledge transfer from other industries into global public health. We examined a partnership designed to improve the availability of medical supplies in Tanzania by transferring knowledge from The Coca-Cola system to Tanzania’s Medical Stores Department (MSD). We conducted a process evaluation including in-depth interviews with 70 participants between July 2011 and May 2014, corresponding to each phase of the partnership, with focus on challenges and strategies to address them, as well as benefits perceived by partners. Partners faced challenges in (1) identifying relevant knowledge to transfer, (2) translating operational solutions from Coca-Cola to MSD, and (3) maintaining momentum between project phases. Strategies to respond to these challenges emerged through real-time problem solving and included (1) leveraging the receptivity of MSD leadership, (2) engaging a boundary spanner to identify knowledge to transfer, (3) promoting local recognition of commonalities across industries, (4) engaging external technical experts to manage translation activities, (5) developing tools with visible benefits for MSD, (6) investing in local relationships, and (7) providing time and space for the partnership model to evolve. Benefits of the partnership perceived by MSD staff included enhanced collaboration and communication, more proactive orientations in managing operations, and greater attention to performance management. Benefits perceived by Coca-Cola staff included strengthened knowledge transfer capability and enhanced job satisfaction. Linking theoretical constructs with practical experiences from the field, we highlight the challenges, emergent strategies, and perceived benefits of a partnership across industry boundaries that may be useful to others seeking to promote the transfer of knowledge to improve global health. PMID:29121051
Study on heat transfer coefficients during cooling of PET bottles for food beverages
NASA Astrophysics Data System (ADS)
Liga, Antonio; Montesanto, Salvatore; Mannella, Gianluca A.; La Carrubba, Vincenzo; Brucato, Valerio; Cammalleri, Marco
2016-08-01
The heat transfer properties of different cooling systems dealing with Poly-Ethylene-Terephthalate (PET) bottles were investigated. The heat transfer coefficient (Ug) was measured in various fluid dynamic conditions. Cooling media were either air or water. It was shown that heat transfer coefficients are strongly affected by fluid dynamics conditions, and range from 10 W/m2 K to nearly 400 W/m2 K. PET bottle thickness effect on Ug was shown to become relevant under faster fluid dynamics regimes.
Transferring Codified Knowledge: Socio-Technical versus Top-Down Approaches
ERIC Educational Resources Information Center
Guzman, Gustavo; Trivelato, Luiz F.
2008-01-01
Purpose: This paper aims to analyse and evaluate the transfer process of codified knowledge (CK) performed under two different approaches: the "socio-technical" and the "top-down". It is argued that the socio-technical approach supports the transfer of CK better than the top-down approach. Design/methodology/approach: Case study methodology was…
Knowledge Transfer between Two Geographically Distant Action Research Teams
ERIC Educational Resources Information Center
Desmarais, Lise; Parent, Robert; Leclerc, Louise; Raymond, Lysanne; MacKinnon, Scott; Vezina, Nicole
2009-01-01
Purpose: The objective of this study is to observe and document the transfer of a train the trainers program in knife sharpening and steeling. This knowledge transfer involved two groups of researchers: the experts and the learners. These groups are from geographically dispersed regions and evolve in distinct contexts by their language and…
Maintaining the Transfer of In-Service Teachers' Training in the Workplace
ERIC Educational Resources Information Center
Cheng, Eddie W. L.
2016-01-01
Professional training and development is a major component of updating teachers' pedagogical knowledge and skills. However, transferring such knowledge and skill may not always be successful. Based on the theory of planned behaviour (TPB), the present study has developed a model specifying the factors affecting transfer maintenance intention and…
NASA Astrophysics Data System (ADS)
Hübner, R.; Heller, K.; Günther, T.; Kleber, A.
2015-01-01
Besides floodplains, hillslopes are basic units that mainly control water movement and flow pathways within catchments of subdued mountain ranges. The structure of their shallow subsurface affects water balance, e.g. infiltration, retention, and runoff. Nevertheless, there is still a gap in the knowledge of the hydrological dynamics on hillslopes, notably due to the lack of generalization and transferability. This study presents a robust multi-method framework of electrical resistivity tomography (ERT) in addition to hydrometric point measurements, transferring hydrometric data into higher spatial scales to obtain additional patterns of distribution and dynamics of soil moisture on a hillslope. A geoelectrical monitoring in a small catchment in the eastern Ore Mountains was carried out at weekly intervals from May to December 2008 to image seasonal moisture dynamics on the hillslope scale. To link water content and electrical resistivity, the parameters of Archie's law were determined using different core samples. To optimize inversion parameters and methods, the derived spatial and temporal water content distribution was compared to tensiometer data. The results from ERT measurements show a strong correlation with the hydrometric data. The response is congruent to the soil tension data. Water content calculated from the ERT profile shows similar variations as that of water content from soil moisture sensors. Consequently, soil moisture dynamics on the hillslope scale may be determined not only by expensive invasive punctual hydrometric measurements, but also by minimally invasive time-lapse ERT, provided that pedo-/petrophysical relationships are known. Since ERT integrates larger spatial scales, a combination with hydrometric point measurements improves the understanding of the ongoing hydrological processes and better suits identification of heterogeneities.
ERIC Educational Resources Information Center
Delfmann, Heike; Koster, Sierdjan
2012-01-01
Knowledge transfer (KT) between higher education institutions (HEIs) and businesses is seen as a key element of innovation in knowledge-driven economies: HEIs generate knowledge that can be adopted in the regional economy. This process of valorization has been studied extensively, mainly with a focus on universities. In the Netherlands, there is a…
Rowe, Nicholas; Ilic, Dragan
2009-12-08
Research knowledge is commonly facilitated at conferences via oral presentations, poster presentations and workshops. Current literature exploring the efficacy of academic posters is however limited. The purpose of this initial study was to explore the perceptions of academic poster presentation, together with its benefits and limitations as an effective mechanism for academic knowledge transfer and contribute to the available academic data. A survey was distributed to 88 delegates who presented academic posters at two Releasing Research and Enterprise Potential conferences in June 2007 and June 2008 at Bournemouth University. This survey addressed attitude and opinion items, together with their general experiences of poster presentations. Descriptive statistics were performed on the responses. A 39% return was achieved with the majority of respondents believing that posters are a good medium for transferring knowledge and a valid form of academic publication. Visual appeal was cited as more influential than subject content, with 94% agreeing that poster imagery is most likely to draw viewer's attention. Respondents also believed that posters must be accompanied by their author in order to effectively communicate the academic content. This pilot study is the first to explore perceptions of the academic poster as a medium for knowledge transfer. Given that academic posters rely heavily on visual appeal and direct author interaction, the medium requires greater flexibility in their design to promote effective knowledge transfer. This paper introduces the concept of the IT-based 'MediaPoster' so as to address the issues raised within published literature and subsequently enhance knowledge-transfer within the field of academic medicine.
Zhao, Jing; Wang, Mei; Fu, Aiyun; Yang, Hongfang; Bu, Yuxiang
2015-08-03
We present an ab initio molecular dynamics (AIMD) simulation study into the transfer dynamics of an excess electron from its cavity-shaped hydrated electron state to a hydrated nucleobase (NB)-bound state. In contrast to the traditional view that electron localization at NBs (G/A/C/T), which is the first step for electron-induced DNA damage, is related only to dry or prehydrated electrons, and a fully hydrated electron no longer transfers to NBs, our AIMD simulations indicate that a fully hydrated electron can still transfer to NBs. We monitored the transfer dynamics of fully hydrated electrons towards hydrated NBs in aqueous solutions by using AIMD simulations and found that due to solution-structure fluctuation and attraction of NBs, a fully hydrated electron can transfer to a NB gradually over time. Concurrently, the hydrated electron cavity gradually reorganizes, distorts, and even breaks. The transfer could be completed in about 120-200 fs in four aqueous NB solutions, depending on the electron-binding ability of hydrated NBs and the structural fluctuation of the solution. The transferring electron resides in the π*-type lowest unoccupied molecular orbital of the NB, which leads to a hydrated NB anion. Clearly, the observed transfer of hydrated electrons can be attributed to the strong electron-binding ability of hydrated NBs over the hydrated electron cavity, which is the driving force, and the transfer dynamics is structure-fluctuation controlled. This work provides new insights into the evolution dynamics of hydrated electrons and provides some helpful information for understanding the DNA-damage mechanism in solution. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Cambon, Linda; Alla, François
2013-01-01
It is becoming increasingly necessary, in France, to develop a more efficient public health policy and define research in terms of the perspective of its use for public decisions and clinical practice. One possible solution consists of knowledge transfer and sharing based on a continuous exchange and interaction process between scientists and potential users of research data - field workers and health policy decision-makers. Such a process would involve collaboration with users to help them apply the evidence produced by research as well as the mobilization of research scientists to develop research more adapted to needs. This article defines the goals of development of knowledge transfer in the French setting. The conceptual bases are defined and four strategic axes and their operational modalities are developed. This proposal also integrates all of the public authorities concerned: promote knowledge transfer; reinforce observation and diffusion of evidence and its usability; promote the development of more adapted public health research by facilitating research scientist /research data user relationships; assist the various parties in the exchange and sharing of knowledge. Apart from improving the efficiency of health policies, the development of knowledge transfer and sharing would also strengthen the credibility of certain intervention strategies, especially in the field of prevention, by designing evidence-based strategies.
Ilic, Dragan; Rowe, Nicholas
2013-03-01
Poster presentations are a common form of presenting health information at conferences and in the community. Anecdotal evidence within the discipline indicates that health information framed in a poster presentation may be an effective method of knowledge transfer. A state of the art review of the literature was performed to determine the effectiveness of poster presentations on knowledge transfer. Electronic searches of various electronic databases were performed for studies published until 2012. Studies were eligible for inclusion if they provided empirical data on the effectiveness of poster presentations on changes in participant knowledge, attitude or behaviour. A total of 51 studies were identified through the database searches, of which 15 met the inclusion criteria. No study evaluated the effectiveness of posters in comparison with other educational interventions. Most studies utilised a before/after methodology, with the common conclusion that posters elicit greatest effectiveness in knowledge transfer when integrated with other educational modalities. The poster presentation is a commonly used format for communicating information within the academic and public health fields. Evidence from well-designed studies comparing posters to other educational modalities is required to establish an evidence base on the effectiveness of utilising posters in achieving knowledge transfer. © 2013 The authors. Health Information and Libraries Journal © 2013 Health Libraries Group.
Learning to Predict Consequences as a Method of Knowledge Transfer in Reinforcement Learning.
Chalmers, Eric; Contreras, Edgar Bermudez; Robertson, Brandon; Luczak, Artur; Gruber, Aaron
2017-04-17
The reinforcement learning (RL) paradigm allows agents to solve tasks through trial-and-error learning. To be capable of efficient, long-term learning, RL agents should be able to apply knowledge gained in the past to new tasks they may encounter in the future. The ability to predict actions' consequences may facilitate such knowledge transfer. We consider here domains where an RL agent has access to two kinds of information: agent-centric information with constant semantics across tasks, and environment-centric information, which is necessary to solve the task, but with semantics that differ between tasks. For example, in robot navigation, environment-centric information may include the robot's geographic location, while agent-centric information may include sensor readings of various nearby obstacles. We propose that these situations provide an opportunity for a very natural style of knowledge transfer, in which the agent learns to predict actions' environmental consequences using agent-centric information. These predictions contain important information about the affordances and dangers present in a novel environment, and can effectively transfer knowledge from agent-centric to environment-centric learning systems. Using several example problems including spatial navigation and network routing, we show that our knowledge transfer approach can allow faster and lower cost learning than existing alternatives.
NASA Astrophysics Data System (ADS)
Acri, Antonio; Offner, Guenter; Nijman, Eugene; Rejlek, Jan
2016-10-01
Noise legislations and the increasing customer demands determine the Noise Vibration and Harshness (NVH) development of modern commercial vehicles. In order to meet the stringent legislative requirements for the vehicle noise emission, exact knowledge of all vehicle noise sources and their acoustic behavior is required. Transfer path analysis (TPA) is a fairly well established technique for estimating and ranking individual low-frequency noise or vibration contributions via the different transmission paths. Transmission paths from different sources to target points of interest and their contributions can be analyzed by applying TPA. This technique is applied on test measurements, which can only be available on prototypes, at the end of the designing process. In order to overcome the limits of TPA, a numerical transfer path analysis methodology based on the substructuring of a multibody system is proposed in this paper. Being based on numerical simulation, this methodology can be performed starting from the first steps of the designing process. The main target of the proposed methodology is to get information of noise sources contributions of a dynamic system considering the possibility to have multiple forces contemporary acting on the system. The contributions of these forces are investigated with particular focus on distribute or moving forces. In this paper, the mathematical basics of the proposed methodology and its advantages in comparison with TPA will be discussed. Then, a dynamic system is investigated with a combination of two methods. Being based on the dynamic substructuring (DS) of the investigated model, the methodology proposed requires the evaluation of the contact forces at interfaces, which are computed with a flexible multi-body dynamic (FMBD) simulation. Then, the structure-borne noise paths are computed with the wave based method (WBM). As an example application a 4-cylinder engine is investigated and the proposed methodology is applied on the engine block. The aim is to get accurate and clear relationships between excitations and responses of the simulated dynamic system, analyzing the noise and vibrational sources inside a car engine, showing the main advantages of a numerical methodology.
Delaforge, Elise; Kragelj, Jaka; Tengo, Laura; Palencia, Andrés; Milles, Sigrid; Bouvignies, Guillaume; Salvi, Nicola; Blackledge, Martin; Jensen, Malene Ringkjøbing
2018-01-24
Intrinsically disordered proteins (IDPs) display a large number of interaction modes including folding-upon-binding, binding without major structural transitions, or binding through highly dynamic, so-called fuzzy, complexes. The vast majority of experimental information about IDP binding modes have been inferred from crystal structures of proteins in complex with short peptides of IDPs. However, crystal structures provide a mainly static view of the complexes and do not give information about the conformational dynamics experienced by the IDP in the bound state. Knowledge of the dynamics of IDP complexes is of fundamental importance to understand how IDPs engage in highly specific interactions without concomitantly high binding affinity. Here, we combine rotating-frame R 1ρ , Carr-Purcell-Meiboom Gill relaxation dispersion as well as chemical exchange saturation transfer to decipher the dynamic interaction profile of an IDP in complex with its partner. We apply the approach to the dynamic signaling complex formed between the mitogen-activated protein kinase (MAPK) p38α and the intrinsically disordered regulatory domain of the MAPK kinase MKK4. Our study demonstrates that MKK4 employs a subtle combination of interaction modes in order to bind to p38α, leading to a complex displaying significantly different dynamics across the bound regions.
Influences of system uncertainties on the numerical transfer path analysis of engine systems
NASA Astrophysics Data System (ADS)
Acri, A.; Nijman, E.; Acri, A.; Offner, G.
2017-10-01
Practical mechanical systems operate with some degree of uncertainty. In numerical models uncertainties can result from poorly known or variable parameters, from geometrical approximation, from discretization or numerical errors, from uncertain inputs or from rapidly changing forcing that can be best described in a stochastic framework. Recently, random matrix theory was introduced to take parameter uncertainties into account in numerical modeling problems. In particular in this paper, Wishart random matrix theory is applied on a multi-body dynamic system to generate random variations of the properties of system components. Multi-body dynamics is a powerful numerical tool largely implemented during the design of new engines. In this paper the influence of model parameter variability on the results obtained from the multi-body simulation of engine dynamics is investigated. The aim is to define a methodology to properly assess and rank system sources when dealing with uncertainties. Particular attention is paid to the influence of these uncertainties on the analysis and the assessment of the different engine vibration sources. Examples of the effects of different levels of uncertainties are illustrated by means of examples using a representative numerical powertrain model. A numerical transfer path analysis, based on system dynamic substructuring, is used to derive and assess the internal engine vibration sources. The results obtained from this analysis are used to derive correlations between parameter uncertainties and statistical distribution of results. The derived statistical information can be used to advance the knowledge of the multi-body analysis and the assessment of system sources when uncertainties in model parameters are considered.
ERIC Educational Resources Information Center
Ozdemir, Omer F.
2013-01-01
The purpose of this study is to understand the nature of pre-instructional knowledge transferred by students into problem situations and the change process on students' knowledge system during classroom discussions. This study was framed by two interrelated theoretical frameworks on knowledge structures, phenomenological primitives and…
ERIC Educational Resources Information Center
Rhodes, Jo; Lok, Peter; Hung, Richard Yu-Yuan; Fang, Shih-Chieh
2008-01-01
Purpose: The purpose of this paper is to set out to examine the relationships of organizational learning, social capital and the effectiveness of knowledge transfer and perceived organisational performance. Integrating organizational learning capability with social capital networks to shape a holistic knowledge sharing and management enterprise…
ERIC Educational Resources Information Center
de Pablos, Patricia Ordonez
2006-01-01
Purpose: The purpose of this paper is to analyse knowledge transfers in transnational corporations. Design/methodology/approach: The paper develops a conceptual framework for the analysis of knowledge flow transfers in transnationals. Based on this theoretical framework, the paper propose's research hypotheses and builds a causal model that links…
Mechanical model development of rolling bearing-rotor systems: A review
NASA Astrophysics Data System (ADS)
Cao, Hongrui; Niu, Linkai; Xi, Songtao; Chen, Xuefeng
2018-03-01
The rolling bearing rotor (RBR) system is the kernel of many rotating machines, which affects the performance of the whole machine. Over the past decades, extensive research work has been carried out to investigate the dynamic behavior of RBR systems. However, to the best of the authors' knowledge, no comprehensive review on RBR modelling has been reported yet. To address this gap in the literature, this paper reviews and critically discusses the current progress of mechanical model development of RBR systems, and identifies future trends for research. Firstly, five kinds of rolling bearing models, i.e., the lumped-parameter model, the quasi-static model, the quasi-dynamic model, the dynamic model, and the finite element (FE) model are summarized. Then, the coupled modelling between bearing models and various rotor models including De Laval/Jeffcott rotor, rigid rotor, transfer matrix method (TMM) models and FE models are presented. Finally, the paper discusses the key challenges of previous works and provides new insights into understanding of RBR systems for their advanced future engineering applications.
ERIC Educational Resources Information Center
Villanueva-Felez, Africa; Bekkers, Rudi; Molas-Gallart, Jordi
2010-01-01
In recent years, considerable attention has been paid to the effectiveness of knowledge transfer processes between academia and industry. Although there is growing evidence that the characteristics of individual researchers are important when explaining cases of successful transfer, few studies have taken the individual researcher as their unit of…
ERIC Educational Resources Information Center
Khost, Peter H.
2015-01-01
Most higher education institutions lack a program that promotes students' transfer--that is, reapplication or repurposing--of writing skills and knowledge across the curriculum, a phenomenon that research shows does not tend to happen without deliberate sustained support. This article introduces an online instrument, the Writer's Individualized…
Travelling and Embedded Policy: The Case of Knowledge Transfer
ERIC Educational Resources Information Center
Ozga, Jenny; Jones, Robert
2006-01-01
Knowledge transfer (KT) has entered the higher education arena in the UK as the "third sector" of higher education activity--along with research and teaching. Its antecedents lie in the commercialization and technology transfer of the late 1980s and 1990s, and this business-like orientation remains dominant in the KT policy discourse.…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Abboud, Alexander William; Guillen, Donna Post
2016-01-01
At the Hanford site, radioactive waste stored in underground tanks is slated for vitrification for final disposal. A comprehensive knowledge of the glass batch melting process will be useful in optimizing the process, which could potentially reduce the cost and duration of this multi-billion dollar cleanup effort. We are developing a high-fidelity heat transfer model of a Joule-heated ceramic lined melter to improve the understanding of the complex, inter-related processes occurring with the melter. The glass conversion rates in the cold cap layer are dependent on promoting efficient heat transfer. In practice, heat transfer is augmented by inserting air bubblersmore » into the molten glass. However, the computational simulations must be validated to provide confidence in the solutions. As part of a larger validation procedure, it is beneficial to split the physics of the melter into smaller systems to validate individually. The substitution of molten glass for a simulant liquid with similar density and viscosity at room temperature provides a way to study mixing through bubbling as an isolated effect without considering the heat transfer dynamics. The simulation results are compared to experimental data obtained by the Vitreous State Laboratory at the Catholic University of America using bubblers placed within a large acrylic tank that is similar in scale to a pilot glass waste melter. Comparisons are made for surface area of the rising air bubbles between experiments and CFD simulations for a variety of air flow rates and bubble injection depths. Also, computed bubble rise velocity is compared to a well-accepted expression for bubble terminal velocity.« less
Optimizing Outcome in the University-Industry Technology Transfer Projects
NASA Astrophysics Data System (ADS)
Alavi, Hamed; Hąbek, Patrycja
2016-06-01
Transferring inventions of academic scientists to private enterprises for the purpose of commercialization is long known as University-Industry (firm) Technology Transfer While the importance of this phenomenon is simultaneously raising in public and private sector, only a part of patented academic inventions succeed in passing the process of commercialization. Despite the fact that formal Technology Transfer process and licencing of patented innovations to third party is the main legal tool for safeguarding rights of academic inventors in commercialization of their inventions, it is not sufficient for transmitting tacit knowledge which is necessary in exploitation of transferred technology. Existence of reciprocal and complementary relations between formal and informal technology transfer process has resulted in formation of different models for university-industry organizational collaboration or even integration where licensee firms keep contact with academic inventors after gaining legal right for commercialization of their patented invention. Current paper argues that despite necessity for patents to legally pass the right of commercialization of an invention, they are not sufficient for complete knowledge transmission in the process of technology transfer. Lack of efficiency of formal mechanism to end the Technology Transfer loop makes an opportunity to create innovative interpersonal and organizational connections among patentee and licensee company. With emphasize on need for further elaboration of informal mechanisms as critical and underappreciated aspect of technology transfer process, article will try to answer the questions of how to optimize knowledge transmission process in the framework of University-Industry Technology Transfer Projects? What is the theoretical basis for university-industry technology transfer process? What are organization collaborative models which can enhance overall performance by improving transmission of knowledge in University- Firm Technology Transfer process?
Interactive knowledge networks for interdisciplinary course navigation within Moodle.
Scherl, Andre; Dethleffsen, Kathrin; Meyer, Michael
2012-12-01
Web-based hypermedia learning environments are widely used in modern education and seem particularly well suited for interdisciplinary learning. Previous work has identified guidance through these complex environments as a crucial problem of their acceptance and efficiency. We reasoned that map-based navigation might provide straightforward and effortless orientation. To achieve this, we developed a clickable and user-oriented concept map-based navigation plugin. This tool is implemented as an extension of Moodle, a widely used learning management system. It visualizes inner and interdisciplinary relations between learning objects and is generated dynamically depending on user set parameters and interactions. This plugin leaves the choice of navigation type to the user and supports direct guidance. Previously developed and evaluated face-to-face interdisciplinary learning materials bridging physiology and physics courses of a medical curriculum were integrated as learning objects, the relations of which were defined by metadata. Learning objects included text pages, self-assessments, videos, animations, and simulations. In a field study, we analyzed the effects of this learning environment on physiology and physics knowledge as well as the transfer ability of third-term medical students. Data were generated from pre- and posttest questionnaires and from tracking student navigation. Use of the hypermedia environment resulted in a significant increase of knowledge and transfer capability. Furthermore, the efficiency of learning was enhanced. We conclude that hypermedia environments based on Moodle and enriched by concept map-based navigation tools can significantly support interdisciplinary learning. Implementation of adaptivity may further strengthen this approach.
Yang, Zhiliang; Dienes, Zoltan
2013-01-01
People can implicitly learn a connection between linguistic forms and meanings, for example between specific determiners (e.g. this, that…) and the type of nouns to which they apply. Li et al (2013) recently found that transfer of form-meaning connections from a concrete domain (height) to an abstract domain (power) was achieved in a metaphor-consistent way without awareness, showing that unconscious knowledge can be abstract and flexibly deployed. The current study aims to determine whether people transfer knowledge of form-meaning connections not only from a concrete domain to an abstract one, but also vice versa, consistent with metaphor representation being bi-directional. With a similar paradigm as used by Li et al, participants learnt form- meaning connections of different domains (concrete vs. abstract) and then were tested on two kinds of generalizations (same and different domain generalization). As predicted, transfer of form-meaning connections occurred bidirectionally when structural knowledge was unconscious. Moreover, the present study also revealed that more transfer occurred between metaphorically related domains when judgment knowledge was conscious (intuition) rather than unconscious (guess). Conscious and unconscious judgment knowledge may have different functional properties. PMID:23844159
Booth, Richard G; Scerbo, Christina Ko; Sinclair, Barbara; Hancock, Michele; Reid, David; Denomy, Eileen
2017-04-01
Little research has been completed exploring knowledge development and transfer from and between simulated and clinical practice settings in nurse education. This study sought to explore the content learned, and the knowledge transferred, in a hybrid mental health clinical course consisting of simulated and clinical setting experiences. A qualitative, interpretive descriptive study design. Clinical practice consisted of six 10-hour shifts in a clinical setting combined with six two-hour simulations. 12 baccalaureate nursing students enrolled in a compressed time frame program at a large, urban, Canadian university participated. Document analysis and a focus group were used to draw thematic representations of content and knowledge transfer between clinical environments (i.e., simulated and clinical settings) using the constant comparative data analysis technique. Four major themes arose: (a) professional nursing behaviors; (b) understanding of the mental health nursing role; (c) confidence gained in interview skills; and, (d) unexpected learning. Nurse educators should further explore the intermingling of simulation and clinical practice in terms of knowledge development and transfer with the goal of preparing students to function within the mental health nursing specialty. Copyright © 2017 Elsevier Ltd. All rights reserved.
Guo, Xunmin; Liu, Zheyun; Song, Qinhua; Wang, Lijuan; Zhong, Dongping
2015-02-26
Many biomimetic chemical systems for repair of UV-damaged DNA showed very low repair efficiency, and the molecular origin is still unknown. Here, we report our systematic characterization of the repair dynamics of a model compound of indole-thymine dimer adduct in three solvents with different polarity. By resolving all elementary steps including three electron-transfer processes and two bond-breaking and bond-formation dynamics with femtosecond resolution, we observed the slow electron injection in 580 ps in water, 4 ns in acetonitrile, and 1.38 ns in dioxane, the fast back electron transfer without repair in 120, 150, and 180 ps, and the slow bond splitting in 550 ps, 1.9 ns, and 4.5 ns, respectively. The dimer bond cleavage is clearly accelerated by the solvent polarity. By comparing with the biological repair machine photolyase with a slow back electron transfer (2.4 ns) and a fast bond cleavage (90 ps), the low repair efficiency in the biomimetic system is mainly determined by the fast back electron transfer and slow bond breakage. We also found that the model system exists in a dynamic heterogeneous C-clamped conformation, leading to a stretched dynamic behavior. In water, we even identified another stacked form with ultrafast cyclic electron transfer, significantly reducing the repair efficiency. Thus, the comparison of the repair efficiency in different solvents is complicated and should be cautious, and only the dynamics by resolving all elementary steps can finally determine the total repair efficiency. Finally, we use the Marcus electron-transfer theory to analyze all electron-transfer reactions and rationalize all observed electron-transfer dynamics.
Explicit instruction of rules interferes with visuomotor skill transfer.
Tanaka, Kanji; Watanabe, Katsumi
2017-06-01
In the present study, we examined the effects of explicit knowledge, obtained through instruction or spontaneous detection, on the transfer of visuomotor sequence learning. In the learning session, participants learned a visuomotor sequence, via trial and error. In the transfer session, the order of the sequence was reversed from that of the learning session. Before the commencement of the transfer session, some participants received explicit instruction regarding the reversal rule (i.e., Instruction group), while the others did not receive any information and were sorted into either an Aware or Unaware group, as assessed by interview conducted after the transfer session. Participants in the Instruction and Aware groups performed with fewer errors than the Unaware group in the transfer session. The participants in the Instruction group showed slower speed than the Aware and Unaware groups in the transfer session, and the sluggishness likely persisted even in late learning. These results suggest that explicit knowledge reduces errors in visuomotor skill transfer, but may interfere with performance speed, particularly when explicit knowledge is provided, as opposed to being spontaneously discovered.
Open Geosciences Knowledge: foster Information Preparedness in a Disaster Resilience Perspective
NASA Astrophysics Data System (ADS)
Rapisardi, Elena; Di Franco, Sabina
2014-05-01
Information in science communication is the ability and the capacity to transfer scientific knowledge to enable the understanding of communication content. Particularly, as stated in many documents and programs (e.g. UNISDR, a clear and correct information on hazards and emergency matters is crucial,either for practitioners or population,to cope with disaster and to allow collaboration to take the best decision. The Open Knowledge is defined as a set of criteria and conditions related to production, use and distribution, that include principles for better access to knowledge. However,knowledge is a pillar to understand the world in itself and to guide human actions and interactions with the environment. A free and open access to knowledge in a wider perspective includes also an ethical topic that is strictly connected to the acting in terms of interactions and responsibilities, in other words with the purpose of knowledge. Focusing on "data" as a technical issue, could displace ethics and responsibility as external issues, enhancing the technical value of data. In this perspective "opening" to an open knowledge perspective could not only solve problems related to the téchne, such as functionalities and efficiency, but it should foster sharing and collaboration expressed through ethics (praxis). The web era frees the information, hence the internet "information deluge" brings to the idea of "encyclopedia" (and of Wikipedia) as a tool to "organize, control and filter" knowledge, to allow communication, knowledge transfer, education, and sense-making. Social media and crowdsourcing have considerable promise for supporting collaborative and innovative ways that reshape the information production and distribution. However, the debate is now facing an important concern related to true/false issues, focusing on validation, and liability. Without any doubt the massive use of Social Media during recent major and minor disasters highlighted a huge need of clear, correct, free and trustworthy information. The challenge is to find models and tools to build an open and structured knowledge to sustain a common understanding in Disaster Resilience [DR] in order to cope with risks and reduce the impact of disaster: to observe natural phenomena, to understand natural hazards dynamics and local risks, to improve and facilitate the access to validated and reliable information.
Kirschner, Denise E; Linderman, Jennifer J
2009-04-01
In addition to traditional and novel experimental approaches to study host-pathogen interactions, mathematical and computer modelling have recently been applied to address open questions in this area. These modelling tools not only offer an additional avenue for exploring disease dynamics at multiple biological scales, but also complement and extend knowledge gained via experimental tools. In this review, we outline four examples where modelling has complemented current experimental techniques in a way that can or has already pushed our knowledge of host-pathogen dynamics forward. Two of the modelling approaches presented go hand in hand with articles in this issue exploring fluorescence resonance energy transfer and two-photon intravital microscopy. Two others explore virtual or 'in silico' deletion and depletion as well as a new method to understand and guide studies in genetic epidemiology. In each of these examples, the complementary nature of modelling and experiment is discussed. We further note that multi-scale modelling may allow us to integrate information across length (molecular, cellular, tissue, organism, population) and time (e.g. seconds to lifetimes). In sum, when combined, these compatible approaches offer new opportunities for understanding host-pathogen interactions.
2009-01-01
Background Research knowledge is commonly facilitated at conferences via oral presentations, poster presentations and workshops. Current literature exploring the efficacy of academic posters is however limited. The purpose of this initial study was to explore the perceptions of academic poster presentation, together with its benefits and limitations as an effective mechanism for academic knowledge transfer and contribute to the available academic data. Methods A survey was distributed to 88 delegates who presented academic posters at two Releasing Research and Enterprise Potential conferences in June 2007 and June 2008 at Bournemouth University. This survey addressed attitude and opinion items, together with their general experiences of poster presentations. Descriptive statistics were performed on the responses. Results A 39% return was achieved with the majority of respondents believing that posters are a good medium for transferring knowledge and a valid form of academic publication. Visual appeal was cited as more influential than subject content, with 94% agreeing that poster imagery is most likely to draw viewer's attention. Respondents also believed that posters must be accompanied by their author in order to effectively communicate the academic content. Conclusion This pilot study is the first to explore perceptions of the academic poster as a medium for knowledge transfer. Given that academic posters rely heavily on visual appeal and direct author interaction, the medium requires greater flexibility in their design to promote effective knowledge transfer. This paper introduces the concept of the IT-based 'MediaPoster' so as to address the issues raised within published literature and subsequently enhance knowledge-transfer within the field of academic medicine. PMID:19995448
Life Planning by Digital Storytelling in a Primary School in Rural Tanzania
ERIC Educational Resources Information Center
Duveskog, Marcus; Tedre, Matti; Sedano, Carolina Islas; Sutinen, Erkki
2012-01-01
Storytelling is one of the earliest forms of knowledge transfer, and parents often use it for teaching their children values and knowledge. Formal schooling, however, is less inclined to use storytelling as a vehicle for knowledge transfer, and even less as a vehicle for modern self-directed, student-centered, and constructionist pedagogy.…
Doing Knowledge Transfer: Engaging Management and Labor with Research on Employee Health and Safety
ERIC Educational Resources Information Center
Kramer, Desre M.; Cole, Donald C.; Leithwood, Kenneth
2004-01-01
In workplace health interventions, engaging management and union decision makers is considered important for the success of the project, yet little research has described the process of making this happen. A case study of a knowledge-transfer process is presented to describe the practices and processes adopted by a knowledge broker who engaged…
The Transfer of Content Knowledge in a Cascade Model of Professional Development
ERIC Educational Resources Information Center
Turner, Fay; Brownhill, Simon; Wilson, Elaine
2017-01-01
A cascade model of professional development presents a particular risk that "knowledge" promoted in a programme will be diluted or distorted as it passes from originators of the programme to local trainers and then to the target teachers. Careful monitoring of trainers' and teachers' knowledge as it is transferred through the system is…
ERIC Educational Resources Information Center
Lean, Jonathan; Tucker, Jonathan
2005-01-01
This paper describes and evaluates a pilot project undertaken in the South West of England to develop a computer-based system for facilitating effective technical knowledge transfer to small and mediumsized enterprises (SMEs). It explores the problem of technical knowledge transfer to SMEs, focusing in particular on the policy context. The…
ERIC Educational Resources Information Center
Alandejani, Jehan
2013-01-01
Studying in another country offers scholars exposure to new cultures and opportunities to learn ways to reform systems and increase knowledge in their countries. Upon returning home, repatriate scholars are expected to utilize what they have learned, which involves implementing or transferring their newly acquired knowledge to their employer…
Disk brake design for cooling improvement using Computational Fluid Dynamics (CFD)
NASA Astrophysics Data System (ADS)
Munisamy, Kannan M.; Shafik, Ramel
2013-06-01
The car disk brake design is improved with two different blade designs compared to the baseline blade design. The two designs were simulated in Computational fluid dynamics (CFD) to obtain heat transfer properties such as Nusselt number and Heat transfer coefficient. The heat transfer property is compared against the baseline design. The improved shape has the highest heat transfer performance. The curved design is inferior to baseline design in heat transfer performance.
ERIC Educational Resources Information Center
Dinsmore, Daniel L.; Baggetta, Peter; Doyle, Stephanie; Loughlin, Sandra M.
2014-01-01
The purpose of this study was to demonstrate that transfer ability (positive and negative) varies depending on the nature of the problems, using the knowledge transfer matrix, as well as being dependent on the individual differences of the learner. A total of 178 participants from the United States and New Zealand completed measures of prior…
ERIC Educational Resources Information Center
Bechtel, Sabrina; Jeschonek, Susanna; Pauen, Sabina
2013-01-01
This study investigated cognitive processes underlying tool use and knowledge transfer in 24-month-olds (N = 123). Following a demonstration, participants chose a tool to reach a reward in a training transfer paradigm. Differing from previous research, various aspects considered to be relevant for children's performance were integrated within the…
ERIC Educational Resources Information Center
Kilbrink, Nina; Bjurulf, Veronica
2013-01-01
In vocational education, teaching and learning are expected to take place in the different learning arenas; schools and workplaces. In such a dual school system, the question of transfer is vital, i.e. how to use knowledge learned in previous situations in new situations. This article is an empirical contribution to research concerning transfer,…
Bromme, Rainer; Beelmann, Andreas
2018-04-01
Many social science-based interventions entail the transfer of evidence-based knowledge to the "target population," because the acquisition and the acceptance of that knowledge are necessary for the intended improvement of behavior or development. Furthermore, the application of a certain prevention program is often legitimated by a reference to science-based reasons such as an evaluation according to scientific standards. Hence, any implementation of evidence-based knowledge and programs is embedded in the public understanding of (social) science. Based on recent research on such public understanding of science, we shall discuss transfer as a process of science communication.
Prior schemata transfer as an account for assessing the intuitive use of new technology.
Fischer, Sandrine; Itoh, Makoto; Inagaki, Toshiyuki
2015-01-01
New devices are considered intuitive when they allow users to transfer prior knowledge. Drawing upon fundamental psychology experiments that distinguish prior knowledge transfer from new schema induction, a procedure was specified for assessing intuitive use. This procedure was tested with 31 participants who, prior to using an on-board computer prototype, studied its screenshots in reading vs. schema induction conditions. Distinct patterns of transfer or induction resulted for features of the prototype whose functions were familiar or unfamiliar, respectively. Though moderated by participants' cognitive style, these findings demonstrated a means for quantitatively assessing transfer of prior knowledge as the operation that underlies intuitive use. Implications for interface evaluation and design, as well as potential improvements to the procedure, are discussed. Copyright © 2014 Elsevier Ltd and The Ergonomics Society. All rights reserved.
Field-based study of connectivity in an agricultural catchment
NASA Astrophysics Data System (ADS)
Lexartza-Artza, I.; Wainwright, J.
2009-12-01
Field-based studies of hydrological connectivity can provide context-specific knowledge that might both help understand dynamic complex systems and contribute to other synthetic or modelling approaches. The importance of such an understanding of catchment processes and also of the knowledge of catchment connections with water bodies and the changes of concentration with scale for Integrated Catchment Management has been increasingly emphasized. To provide a holistic understanding, approaches to the study of connectivity need to include both structural and functional aspects of the system and must consider the processes taking place within and across different temporal and spatial scales. A semi-quantitative nested approach has been used to investigate connectivity and study the interactions and feedbacks between the factors influencing transfer processes in the Ingbirchworth Catchment, in the uplands of the River Don, England. A series of reconnaissance techniques have been combined with monitoring of aspects such as rainfall, runoff, sediment transfer and soil-moisture distribution from plot to catchment scale and with consideration of linkages between land and water bodies. The temporal aspect has also been considered, with a special focus on the temporal distribution of events and the influence of longer term catchment changes such as those in land use and management practices. A variability of responses has been observed in relation to the characteristics of events, land use and scale of observation, with elements traditionally considered as limiting or enhancing connectivity responding differently under changing conditions. Sediment redistribution, reshaping of structure and consequent reinforcing loops can be observed across all land uses and landscape units, but the relevance it terms of effective connectivity of highly connected patches varies as the scale is increased. The knowledge acquired can contribute to recognise emerging processes significant for active land-water connection and thus provide useful knowledge for decision making.
Sieblist, Christian; Jenzsch, Marco; Pohlscheidt, Michael
2016-08-01
The production of monoclonal antibodies by mammalian cell culture in bioreactors up to 25,000 L is state of the art technology in the biotech industry. During the lifecycle of a product, several scale up activities and technology transfers are typically executed to enable the supply chain strategy of a global pharmaceutical company. Given the sensitivity of mammalian cells to physicochemical culture conditions, process and equipment knowledge are critical to avoid impacts on timelines, product quantity and quality. Especially, the fluid dynamics of large scale bioreactors versus small scale models need to be described, and similarity demonstrated, in light of the Quality by Design approach promoted by the FDA. This approach comprises an associated design space which is established during process characterization and validation in bench scale bioreactors. Therefore the establishment of predictive models and simulation tools for major operating conditions of stirred vessels (mixing, mass transfer, and shear force.), based on fundamental engineering principles, have experienced a renaissance in the recent years. This work illustrates the systematic characterization of a large variety of bioreactor designs deployed in a global manufacturing network ranging from small bench scale equipment to large scale production equipment (25,000 L). Several traditional methods to determine power input, mixing, mass transfer and shear force have been used to create a data base and identify differences for various impeller types and configurations in operating ranges typically applied in cell culture processes at manufacturing scale. In addition, extrapolation of different empirical models, e.g. Cooke et al. (Paper presented at the proceedings of the 2nd international conference of bioreactor fluid dynamics, Cranfield, UK, 1988), have been assessed for their validity in these operational ranges. Results for selected designs are shown and serve as examples of structured characterization to enable fast and agile process transfers, scale up and troubleshooting.
Ultrafast direct electron transfer at organic semiconductor and metal interfaces.
Xiang, Bo; Li, Yingmin; Pham, C Huy; Paesani, Francesco; Xiong, Wei
2017-11-01
The ability to control direct electron transfer can facilitate the development of new molecular electronics, light-harvesting materials, and photocatalysis. However, control of direct electron transfer has been rarely reported, and the molecular conformation-electron dynamics relationships remain unclear. We describe direct electron transfer at buried interfaces between an organic polymer semiconductor film and a gold substrate by observing the first dynamical electric field-induced vibrational sum frequency generation (VSFG). In transient electric field-induced VSFG measurements on this system, we observe dynamical responses (<150 fs) that depend on photon energy and polarization, demonstrating that electrons are directly transferred from the Fermi level of gold to the lowest unoccupied molecular orbital of organic semiconductor. Transient spectra further reveal that, although the interfaces are prepared without deliberate alignment control, a subensemble of surface molecules can adopt conformations for direct electron transfer. Density functional theory calculations support the experimental results and ascribe the observed electron transfer to a flat-lying polymer configuration in which electronic orbitals are found to be delocalized across the interface. The present observation of direct electron transfer at complex interfaces and the insights gained into the relationship between molecular conformations and electron dynamics will have implications for implementing novel direct electron transfer in energy materials.
Transfer Wisdom Workshops: Coming to a NASA Center Near You
NASA Technical Reports Server (NTRS)
Lee, Denise
2003-01-01
In november 2001, the APPL Knowledge Sharing Initiative introduced a new product, the transfer wisdom workshop. The idea was to give practitioners at each of the NASA centers the opportunity to engage in a knowledge sharing activity.
An Alternative Expert Knowledge Transfer Model: A Case Study of an Indigenous Storytelling Approach
ERIC Educational Resources Information Center
Spaulding, Roderick Jay
2010-01-01
The increasing complexity of technical work, the demand for highly skilled workers, and the vital challenges facing the world at large have combined to create a need for better ways to transfer knowledge, especially expert knowledge. In this dissertation, I attempted to see if an approach to this process that is more holistic than is typical in…
Knowledge translation of research findings.
Grimshaw, Jeremy M; Eccles, Martin P; Lavis, John N; Hill, Sophie J; Squires, Janet E
2012-05-31
One of the most consistent findings from clinical and health services research is the failure to translate research into practice and policy. As a result of these evidence-practice and policy gaps, patients fail to benefit optimally from advances in healthcare and are exposed to unnecessary risks of iatrogenic harms, and healthcare systems are exposed to unnecessary expenditure resulting in significant opportunity costs. Over the last decade, there has been increasing international policy and research attention on how to reduce the evidence-practice and policy gap. In this paper, we summarise the current concepts and evidence to guide knowledge translation activities, defined as T2 research (the translation of new clinical knowledge into improved health). We structure the article around five key questions: what should be transferred; to whom should research knowledge be transferred; by whom should research knowledge be transferred; how should research knowledge be transferred; and, with what effect should research knowledge be transferred? We suggest that the basic unit of knowledge translation should usually be up-to-date systematic reviews or other syntheses of research findings. Knowledge translators need to identify the key messages for different target audiences and to fashion these in language and knowledge translation products that are easily assimilated by different audiences. The relative importance of knowledge translation to different target audiences will vary by the type of research and appropriate endpoints of knowledge translation may vary across different stakeholder groups. There are a large number of planned knowledge translation models, derived from different disciplinary, contextual (i.e., setting), and target audience viewpoints. Most of these suggest that planned knowledge translation for healthcare professionals and consumers is more likely to be successful if the choice of knowledge translation strategy is informed by an assessment of the likely barriers and facilitators. Although our evidence on the likely effectiveness of different strategies to overcome specific barriers remains incomplete, there is a range of informative systematic reviews of interventions aimed at healthcare professionals and consumers (i.e., patients, family members, and informal carers) and of factors important to research use by policy makers. There is a substantial (if incomplete) evidence base to guide choice of knowledge translation activities targeting healthcare professionals and consumers. The evidence base on the effects of different knowledge translation approaches targeting healthcare policy makers and senior managers is much weaker but there are a profusion of innovative approaches that warrant further evaluation.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the 'NASA/DoD Aerospace Knowledge Diffusion Research Project'. In this report, we summarize the literature on technical reprts and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from five studies of our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report and close with a brief overview of on-going research into the use of the U.S. government technical report as a rhetorical device for transferring federally funded aerospace R&D.
NASA Astrophysics Data System (ADS)
Beasley, Howard H.; Martin, John S.; Klymenko, Victor; Harding, Thomas H.; Verona, Robert W.; Rash, Clarence E.
1995-07-01
A counterphase modulation technique is used to measure the static and dynamic modulation transfer functions for three phosphorus of current interest to U.S. Army aviation helmet-mounted displays (P-1, P-43, and P-53). A family of modulation transfer curves, one for each temporal frequency, is presented for each phosphorus. The measured MFT curves generally support the supposition that phosphorus persistence is a critical parameter in the ability of a CRT display to accurately reproduce contrast modulation transfer in dynamic environments.
NASA Astrophysics Data System (ADS)
Huang, Chong; Radabaugh, Jeffrey P.; Aouad, Rony K.; Lin, Yu; Gal, Thomas J.; Patel, Amit B.; Valentino, Joseph; Shang, Yu; Yu, Guoqiang
2015-07-01
Knowledge of tissue blood flow (BF) changes after free tissue transfer may enable surgeons to predict the failure of flap thrombosis at an early stage. This study used our recently developed noncontact diffuse correlation spectroscopy to monitor dynamic BF changes in free flaps without getting in contact with the targeted tissue. Eight free flaps were elevated in patients with head and neck cancer; one of the flaps failed. Multiple BF measurements probing the transferred tissue were performed during and post the surgical operation. Postoperative BF values were normalized to the intraoperative baselines (assigning "1") for the calculation of relative BF change (rBF). The rBF changes over the seven successful flaps were 1.89±0.15, 2.26±0.13, and 2.43±0.13 (mean±standard error), respectively, on postoperative days 2, 4, and 7. These postoperative values were significantly higher than the intraoperative baseline values (p<0.001), indicating a gradual recovery of flap vascularity after the tissue transfer. By contrast, rBF changes observed from the unsuccessful flaps were 1.14 and 1.34, respectively, on postoperative days 2 and 4, indicating less flow recovery. Measurement of BF recovery after flap anastomosis holds the potential to act early to salvage ischemic flaps.
Huang, Chong; Radabaugh, Jeffrey P.; Aouad, Rony K.; Lin, Yu; Gal, Thomas J.; Patel, Amit B.; Valentino, Joseph; Shang, Yu; Yu, Guoqiang
2015-01-01
Abstract. Knowledge of tissue blood flow (BF) changes after free tissue transfer may enable surgeons to predict the failure of flap thrombosis at an early stage. This study used our recently developed noncontact diffuse correlation spectroscopy to monitor dynamic BF changes in free flaps without getting in contact with the targeted tissue. Eight free flaps were elevated in patients with head and neck cancer; one of the flaps failed. Multiple BF measurements probing the transferred tissue were performed during and post the surgical operation. Postoperative BF values were normalized to the intraoperative baselines (assigning “1”) for the calculation of relative BF change (rBF). The rBF changes over the seven successful flaps were 1.89±0.15, 2.26±0.13, and 2.43±0.13 (mean±standard error), respectively, on postoperative days 2, 4, and 7. These postoperative values were significantly higher than the intraoperative baseline values (p<0.001), indicating a gradual recovery of flap vascularity after the tissue transfer. By contrast, rBF changes observed from the unsuccessful flaps were 1.14 and 1.34, respectively, on postoperative days 2 and 4, indicating less flow recovery. Measurement of BF recovery after flap anastomosis holds the potential to act early to salvage ischemic flaps. PMID:26187444
Enabling the Capture and Sharing of NASA Technical Expertise Through Communities of Practice
NASA Technical Reports Server (NTRS)
Topousis, Daria E.; Dennehy, Cornelius J.; Lebsock, Kenneth L.
2011-01-01
Historically, engineers at the National Aeronautics and Space Administration (NASA) had few opportunities or incentives to share their technical expertise across the Agency. Its center- and project- focused culture often meant that knowledge never left organizational and geographic boundaries. With increasingly complex missions, the closeout of the Shuttle Program, and a new generation entering the workforce, developing a knowledge sharing culture became critical. To address this need, the Office of the Chief Engineer established communities of practice on the NASA Engineering Network. These communities were strategically aligned with NASA's core competencies in such disciplines as avionics, flight mechanics, life support, propulsion, structures, loads and dynamics, human factors, and guidance, navigation, and control. This paper describes the process used to identify and develop communities, from establishing simple websites that compiled discipline-specific resources to fostering a knowledge-sharing environment through collaborative and interactive technologies. It includes qualitative evidence of improved availability and transfer of knowledge. It focuses on pivotal capabilities that increased knowledge exchange such as a custom-made Ask An Expert system, community contact lists, publication of key resources, and submission forms that allowed any user to propose content for the sites. It discusses the peer relationships that developed through the communities and the leadership and infrastructure that made them possible.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Khan, A. Rahman; Barclay, Rebecca O.; Kennedy, John M.
1993-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded (U.S.) R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this paper, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from two surveys (one of five studies) of our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report and close with a brief overview of on-going research into the use of the U.S. government technical report as a rhetorical device for transferring federally funded aerospace R&D.
Knowledge transfer on complex social interventions in public health: a scoping study.
Dagenais, Christian; Malo, Marie; Robert, Émilie; Ouimet, Mathieu; Berthelette, Diane; Ridde, Valéry
2013-01-01
Scientific knowledge can help develop interventions that improve public health. The objectives of this review are (1) to describe the status of research on knowledge transfer strategies in the field of complex social interventions in public health and (2) to identify priorities for future research in this field. A scoping study is an exploratory study. After searching databases of bibliographic references and specialized periodicals, we summarized the relevant studies using a predetermined assessment framework. In-depth analysis focused on the following items: types of knowledge transfer strategies, fields of public health, types of publics, types of utilization, and types of research specifications. From the 1,374 references identified, we selected 26 studies. The strategies targeted mostly administrators of organizations and practitioners. The articles generally dealt with instrumental utilization and most often used qualitative methods. In general, the bias risk for the studies is high. Researchers need to consider the methodological challenges in this field of research in order to improve assessment of more complex knowledge transfer strategies (when they exist), not just diffusion/dissemination strategies and conceptual and persuasive utilization.
Knowledge Transfer on Complex Social Interventions in Public Health: A Scoping Study
Dagenais, Christian; Malo, Marie; Robert, Émilie; Ouimet, Mathieu; Berthelette, Diane; Ridde, Valéry
2013-01-01
Objectives Scientific knowledge can help develop interventions that improve public health. The objectives of this review are (1) to describe the status of research on knowledge transfer strategies in the field of complex social interventions in public health and (2) to identify priorities for future research in this field. Method A scoping study is an exploratory study. After searching databases of bibliographic references and specialized periodicals, we summarized the relevant studies using a predetermined assessment framework. In-depth analysis focused on the following items: types of knowledge transfer strategies, fields of public health, types of publics, types of utilization, and types of research specifications. Results From the 1,374 references identified, we selected 26 studies. The strategies targeted mostly administrators of organizations and practitioners. The articles generally dealt with instrumental utilization and most often used qualitative methods. In general, the bias risk for the studies is high. Conclusion Researchers need to consider the methodological challenges in this field of research in order to improve assessment of more complex knowledge transfer strategies (when they exist), not just diffusion/dissemination strategies and conceptual and persuasive utilization. PMID:24324593
Ghosh, Hirendra N; Verma, Sandeep; Nibbering, Erik T J
2011-02-10
Femtosecond infrared spectroscopy is used to study both forward and backward electron transfer (ET) dynamics between coumarin 337 (C337) and the aromatic amine solvents aniline (AN), N-methylaniline (MAN), and N,N-dimethylaniline (DMAN), where all the aniline solvents can donate an electron but only AN and MAN can form hydrogen bonds with C337. The formation of a hydrogen bond with AN and MAN is confirmed with steady state FT-IR spectroscopy, where the C═O stretching vibration is a direct marker mode for hydrogen bond formation. Transient IR absorption measurements in all solvents show an absorption band at 2166 cm(-1), which has been attributed to the C≡N stretching vibration of the C337 radical anion formed after ET. Forward electron transfer dynamics is found to be biexponential with time constants τ(ET)(1) = 500 fs, τ(ET)(2) = 7 ps in all solvents. Despite the presence of hydrogen bonds of C337 with the solvents AN and MAN, no effect has been found on the forward electron transfer step. Because of the absence of an H/D isotope effect on the forward electron transfer reaction of C337 in AN, hydrogen bonds are understood to play a minor role in mediating electron transfer. In contrast, direct π-orbital overlap between C337 and the aromatic amine solvents causes ultrafast forward electron transfer dynamics. Backward electron transfer dynamics, in contrast, is dependent on the solvent used. Standard Marcus theory explains the observed backward electron transfer rates.
The "erotic transference": some technical and countertransferential difficulties.
Book, H E
1995-01-01
This paper highlights dynamics that may interfere with the therapist's identifying and addressing the erotic transference: (1) deficient training; (2) theoretical orientations that devalue the transference while espousing a "real" relationship including self-disclosure; (3) countertransference responses to the erotic transference; and (4) clinical errors of focusing on the manifest erotic transference while overlooking significant but latent pre-oedipal, oedipal, aggressive, or selfobject issues. Inattention to these dynamics may render the therapist vulnerable to sexual acting out with his patient.
Guzman, Gustavo; Fitzgerald, Janna Anneke; Fulop, Liz; Hayes, Kathryn; Poropat, Arthur; Avery, Mark; Campbell, Steve; Fisher, Ron; Gapp, Rod; Herington, Carmel; McPhail, Ruth; Vecchio, Nerina
2015-01-01
In spite of significant investment in quality programs and activities, there is a persistent struggle to achieve quality outcomes and performance improvements within the constraints and support of sociopolitical parsimonies. Equally, such constraints have intensified the need to better understand the best practice methods for achieving quality improvements in health care organizations over time.This study proposes a conceptual framework to assist with strategies for the copying, transferring, and/or translation of best practice between different health care facilities. Applying a deductive logic, the conceptual framework was developed by blending selected theoretical lenses drawn from the knowledge management and organizational learning literatures. The proposed framework highlighted that (a) major constraints need to be addressed to turn best practices into everyday practices and (b) double-loop learning is an adequate learning mode to copy and to transfer best practices and deuteron learning mode is a more suitable learning mode for translating best practice. We also found that, in complex organizations, copying, transferring, and translating new knowledge is more difficult than in smaller, less complex organizations. We also posit that knowledge translation cannot happen without transfer and copy, and transfer cannot happen without copy of best practices. Hence, an integration of all three learning processes is required for knowledge translation (copy best practice-transfer knowledge about best practice-translation of best practice into new context). In addition, the higher the level of complexity of the organization, the more best practice is tacit oriented and, in this case, the higher the level of K&L capabilities are required to successfully copy, transfer, and/or translate best practices between organizations. The approach provides a framework for assessing organizational context and capabilities to guide copy/transfer/translation of best practices. A roadmap is provided to assist managers and practitioners to select appropriate learning modes for building success and positive systemic change.
Epron, Daniel; Bahn, Michael; Derrien, Delphine; Lattanzi, Fernando Alfredo; Pumpanen, Jukka; Gessler, Arthur; Högberg, Peter; Maillard, Pascale; Dannoura, Masako; Gérant, Dominique; Buchmann, Nina
2012-06-01
Pulse-labelling of trees with stable or radioactive carbon (C) isotopes offers the unique opportunity to trace the fate of labelled CO(2) into the tree and its release to the soil and the atmosphere. Thus, pulse-labelling enables the quantification of C partitioning in forests and the assessment of the role of partitioning in tree growth, resource acquisition and C sequestration. However, this is associated with challenges as regards the choice of a tracer, the methods of tracing labelled C in tree and soil compartments and the quantitative analysis of C dynamics. Based on data from 47 studies, the rate of transfer differs between broadleaved and coniferous species and decreases as temperature and soil water content decrease. Labelled C is rapidly transferred belowground-within a few days or less-and this transfer is slowed down by drought. Half-lives of labelled C in phloem sap (transfer pool) and in mature leaves (source organs) are short, while those of sink organs (growing tissues, seasonal storage) are longer. (13)C measurements in respiratory efflux at high temporal resolution provide the best estimate of the mean residence times of C in respiratory substrate pools, and the best basis for compartmental modelling. Seasonal C dynamics and allocation patterns indicate that sink strength variations are important drivers for C fluxes. We propose a conceptual model for temperate and boreal trees, which considers the use of recently assimilated C versus stored C. We recommend best practices for designing and analysing pulse-labelling experiments, and identify several topics which we consider of prime importance for future research on C allocation in trees: (i) whole-tree C source-sink relations, (ii) C allocation to secondary metabolism, (iii) responses to environmental change, (iv) effects of seasonality versus phenology in and across biomes, and (v) carbon-nitrogen interactions. Substantial progress is expected from emerging technologies, but the largest challenge remains to carry out in situ whole-tree labelling experiments on mature trees to improve our understanding of the environmental and physiological controls on C allocation.
ERIC Educational Resources Information Center
Gergely, Gyorgy; Egyed, Katalin; Kiraly, Ildiko
2007-01-01
Humans are adapted to spontaneously transfer relevant cultural knowledge to conspecifics and to fast-learn the contents of such teaching through a human-specific social learning system called "pedagogy" ( Csibra & Gergely, 2006). Pedagogical knowledge transfer is triggered by specific communicative cues (such as eye-contact, contingent reactivity,…
University-Industry Technology Transfer in Hong Kong
ERIC Educational Resources Information Center
Poon, Patrick S.; Chan, Kan S.
2007-01-01
In the modern knowledge economy, higher educational institutions are being required to deal with commercialising the results of their research, spinning out knowledge-based enterprises and facilitating technology transfer between their research centres and industrial firms. The universities are undergoing changes in institutional and…
ERIC Educational Resources Information Center
Wagner, Joseph F.
2006-01-01
The theoretical perspective outlined here offers an alternative to explanations of knowledge transfer that posit its source in the construction and application of abstract, context-independent knowledge structures. A case study analysis of an undergraduate student's attempt to solve a series of problems related to an elementary statistical…
Hopper, Anita K.
2013-01-01
Transfer RNAs (tRNAs) are essential for protein synthesis. In eukaryotes, tRNA biosynthesis employs a specialized RNA polymerase that generates initial transcripts that must be subsequently altered via a multitude of post-transcriptional steps before the tRNAs beome mature molecules that function in protein synthesis. Genetic, genomic, biochemical, and cell biological approaches possible in the powerful Saccharomyces cerevisiae system have led to exciting advances in our understandings of tRNA post-transcriptional processing as well as to novel insights into tRNA turnover and tRNA subcellular dynamics. tRNA processing steps include removal of transcribed leader and trailer sequences, addition of CCA to the 3′ mature sequence and, for tRNAHis, addition of a 5′ G. About 20% of yeast tRNAs are encoded by intron-containing genes. The three-step splicing process to remove the introns surprisingly occurs in the cytoplasm in yeast and each of the splicing enzymes appears to moonlight in functions in addition to tRNA splicing. There are 25 different nucleoside modifications that are added post-transcriptionally, creating tRNAs in which ∼15% of the residues are nucleosides other than A, G, U, or C. These modified nucleosides serve numerous important functions including tRNA discrimination, translation fidelity, and tRNA quality control. Mature tRNAs are very stable, but nevertheless yeast cells possess multiple pathways to degrade inappropriately processed or folded tRNAs. Mature tRNAs are also dynamic in cells, moving from the cytoplasm to the nucleus and back again to the cytoplasm; the mechanism and function of this retrograde process is poorly understood. Here, the state of knowledge for tRNA post-transcriptional processing, turnover, and subcellular dynamics is addressed, highlighting the questions that remain. PMID:23633143
Stang, Christoph; Bakanov, Nikita; Schulz, Ralf
2016-01-01
Knowledge on the dynamics and the durability of the processes governing the mitigation of pesticide loads by aquatic vegetation in vegetated streams, which are characterized by dynamic discharge regimes and short chemical residence times, is scarce. In a static long-term experiment (48 h), the dissipation of five pesticides from the aqueous phase followed a biphasic pattern in the presence of aquatic macrophytes. A dynamic concentration decrease driven by sorption to the macrophytes ranged from 8.3 to 60.4% for isoproturon and bifenox, respectively, within the first 2 h of exposure. While the aqueous concentrations of imidacloprid, isoproturon, and tebufenozide remained constant thereafter, the continuous but decelerated concentration decrease of difenoconazole and bifenox in the water-macrophyte systems used here was assumed to be attributed to macrophyte-induced degradation processes. In addition, a semi-static short-term experiment was conducted, where macrophytes were transferred to uncontaminated medium after 2 h of exposure to simulate a transient pesticide peak. In the first part of the experiment, adsorption to macrophytes resulted in partitioning coefficients (logK D_Adsorp) ranging from 0.2 for imidacloprid to 2.2 for bifenox. One hour after the macrophytes were transferred to the uncontaminated medium, desorption of the compounds from the macrophytes resulted in a new phase equilibrium and K D_Desorp values of 1.46 for difenoconazole and 1.95 for bifenox were determined. A correlation analysis revealed the best match between the compound affinity to adsorb to macrophytes (expressed as K D_Adsorp) and their soil organic carbon-water partitioning coefficient (K OC) compared to their octanol-water partitioning coefficient (K OW) or a mathematically derived partitioning coefficient.
NASA Astrophysics Data System (ADS)
Orr, Barron
2015-04-01
By any measure, our efforts to protect and restore the environment have failed to keep pace with environmental change, despite extraordinary scientific advances. Clearly there is a problem in knowledge transfer, which is often blamed on limited public awareness, misunderstanding or even apathy. Whether it's moving research to practice, informing policy, or educating the public on the environmental challenges of our time, our track record is poor. A major part of our failure lies in how scientists and practitioners understand (or misunderstand) and practice knowledge transfer. What actually drives knowledge acquisition and the motivation to gain knowledge, and what does this say about the methods used for knowledge transfer? Is the problem a supply issue (deficit of knowledge) or a demand issue (personal relevance)? The false assumptions that spin out of how we conceptualize knowledge acquisition lead to investment in knowledge transfer balanced heavily in "science communication" and "awareness raising" activities that tend to be unidirectional, top-down, and rarely linked to personal interests. Successful adaptation to environmental change requires a theoretical and practical understanding of coupled natural-human systems as well as advances in bridging knowledge systems and the science-society gap. To be effective, this means a "translational science" approach that promotes the capture and integration of scientific and local knowledge, addresses the influences of scale (biophysically, socially, institutionally), encourages mutual learning among all parties, and builds capacity as part of the process. The facilitation and translation of information and meanings among stakeholders can lead to the co-production of knowledge, more informed decision making, and in a very pragmatic way, more effective use of assessments and other products of scientific discovery. The purpose of this presentation is to shed light on what underlies the majority of investment in knowledge transfer, the false assumptions that result, and the ramifications for the methods employed the vast majority of the time by the scientific community. The case for public engagement and participatory approaches will be made, followed by a brief survey of the theories, methods and tools that make engagement possible and effective. Successful adaptation to environmental change requires a much stronger link between science and society. While science communication and awareness raising are necessary, they are much more effective when coupled with robust, formative, and participatory approaches to stakeholder engagement. This is necessary for successful land-based adaptation to environmental change.
Color transfer between high-dynamic-range images
NASA Astrophysics Data System (ADS)
Hristova, Hristina; Cozot, Rémi; Le Meur, Olivier; Bouatouch, Kadi
2015-09-01
Color transfer methods alter the look of a source image with regards to a reference image. So far, the proposed color transfer methods have been limited to low-dynamic-range (LDR) images. Unlike LDR images, which are display-dependent, high-dynamic-range (HDR) images contain real physical values of the world luminance and are able to capture high luminance variations and finest details of real world scenes. Therefore, there exists a strong discrepancy between the two types of images. In this paper, we bridge the gap between the color transfer domain and the HDR imagery by introducing HDR extensions to LDR color transfer methods. We tackle the main issues of applying a color transfer between two HDR images. First, to address the nature of light and color distributions in the context of HDR imagery, we carry out modifications of traditional color spaces. Furthermore, we ensure high precision in the quantization of the dynamic range for histogram computations. As image clustering (based on light and colors) proved to be an important aspect of color transfer, we analyze it and adapt it to the HDR domain. Our framework has been applied to several state-of-the-art color transfer methods. Qualitative experiments have shown that results obtained with the proposed adaptation approach exhibit less artifacts and are visually more pleasing than results obtained when straightforwardly applying existing color transfer methods to HDR images.
The metabolic response to excitotoxicity - lessons from single-cell imaging.
Connolly, Niamh M C; Prehn, Jochen H M
2015-04-01
Excitotoxicity is a pathological process implicated in neuronal death during ischaemia, traumatic brain injuries and neurodegenerative diseases. Excitotoxicity is caused by excess levels of glutamate and over-activation of NMDA or calcium-permeable AMPA receptors on neuronal membranes, leading to ionic influx, energetic stress and potential neuronal death. The metabolic response of neurons to excitotoxicity is complex and plays a key role in the ability of the neuron to adapt and recover from such an insult. Single-cell imaging is a powerful experimental technique that can be used to study the neuronal metabolic response to excitotoxicity in vitro and, increasingly, in vivo. Here, we review some of the knowledge of the neuronal metabolic response to excitotoxicity gained from in vitro single-cell imaging, including calcium and ATP dynamics and their effects on mitochondrial function, along with the contribution of glucose metabolism, oxidative stress and additional neuroprotective signalling mechanisms. Future work will combine knowledge gained from single-cell imaging with data from biochemical and computational techniques to garner holistic information about the metabolic response to excitotoxicity at the whole brain level and transfer this knowledge to a clinical setting.
Dynamic mass transfer methods have been developed to better describe the interaction of the aerosol population with semi-volatile species such as nitrate, ammonia, and chloride. Unfortunately, these dynamic methods are computationally expensive. Assumptions are often made to r...
Winship, Kathy
2012-01-01
Concern over the impending retirement of several top-level managers led a county agency to engage in efforts aimed at more efficient succession management. Administrators developed plans to prevent the loss of invaluable knowledge and wisdom accompanying retirement of experienced agency leaders. The agency's Director of Finance (DoF) was one of the first key figures projected to retire, and a succession plan was implemented to transfer his knowledge for use after his departure. The knowledge transfer process involved three stages, including: (1) employing the DoF as teacher, having him develop curricula and conduct trainings; (2) engaging the DoF as mentor, allowing an existing staff member and the DoF's successor to shadow and be coached by the DoF; and (3) developing a knowledge management system that could be used after the DoF departed. This case study describes the knowledge transfer process and experiences shared by the DoF and this agency. Copyright © Taylor & Francis Group, LLC
Facilitating Learning in Multidisciplinary Groups with Transactive CSCL Scripts
ERIC Educational Resources Information Center
Noroozi, Omid; Teasley, Stephanie D.; Biemans, Harm J. A.; Weinberger, Armin; Mulder, Martin
2013-01-01
Knowledge sharing and transfer are essential for learning in groups, especially when group members have different disciplinary expertise and collaborate online. Computer-Supported Collaborative Learning (CSCL) environments have been designed to facilitate transactive knowledge sharing and transfer in collaborative problem-solving settings. This…
Knowledge Transfer in Social Work: The Role of Grey Documentation.
ERIC Educational Resources Information Center
Berman, Yitzhak
1995-01-01
Discusses scholarly journals in the field of social work, information sources for social work practitioners versus researchers, and grey documentation as an alternative means of knowledge transfer. Highlights include research versus practice; grey documentation and scientific credibility; and dissemination of grey literature. (LRW)
NASA Astrophysics Data System (ADS)
Dotterweich, Markus
2017-04-01
In the last few years, the use of smartphone-apps has become a daily routine in our life. However, only a few approaches have been undertaken to use apps for transferring scientific knowledge to the public audience. The development of learning apps or serious games requires large efforts and several levels of simplification which is different to traditional text books or learning webpages. Current approaches often lack a connection to the real life and/or innovative gamification concepts. Another almost untapped potential is the use of Virtual Reality, a fast growing technology which replicates a virtual environment in order to simulate physical experiences in artificial or real worlds. Hence, smartphone-apps and VR provides new opportunities for capacity building, knowledge transfer, citizen science or interactive engagement in the realm of environmental sciences. This presentation will show some examples and discuss the advantages of these immersive approaches to improve the knowledge transfer between scientists and citizens and to stimulate actions in the real world.
Curran, Mary K
2014-05-01
The American Nurses Association advocates for nursing professional development (NPD) specialists to have an earned graduate degree, as well as educational and clinical expertise. However, many NPD specialists have limited exposure to adult learning theory. Limited exposure to adult learning theory may affect NPD educational practices, learning outcomes, organizational knowledge transfer, and subsequently, the professional development of the nurses they serve and quality of nursing care. An examination of current teaching practices may reveal opportunities for NPD specialists to enhance educational methods to promote learning, learning transfer, and organizational knowledge and excellence. This article, the first in a two-part series, examines best practices of adult learning theories, nursing professional development, curriculum design, and knowledge transfer. Part II details the results of a correlational study that examined the effects of four variables on the use of adult learning theory to guide curriculum development for NPD specialists in hospitals. Copyright 2014, SLACK Incorporated.
Exploring the networking behaviors of hospital organizations.
Di Vincenzo, Fausto
2018-05-08
Despite an extensive body of knowledge exists on network outcomes and on how hospital network structures may contribute to the creation of outcomes at different levels of analysis, less attention has been paid to understanding how and why hospital organizational networks evolve and change. The aim of this paper is to study the dynamics of networking behaviors of hospital organizations. Stochastic actor-based model for network dynamics was used to quantitatively examine data covering six-years of patient transfer relations among 35 hospital organizations. Specifically, the study investigated about determinants of patient transfer evolution modeling partner selection choice as a combination of multiple organizational attributes and endogenous network-based processes. The results indicate that having overlapping specialties and treating patients with the same case-mix decrease the likelihood of observing network ties between hospitals. Also, results revealed as geographical proximity and membership of the same LHA have a positive impact on the networking behavior of hospitals organizations, there is a propensity in the network to choose larger hospitals as partners, and to transfer patients between hospitals facing similar levels of operational uncertainty. Organizational attributes (overlapping specialties and case-mix), institutional factors (LHA), and geographical proximity matter in the formation and shaping of hospital networks over time. Managers can benefit from the use of these findings by clearly identifying the role and strategic positioning of their hospital with respect to the entire network. Social network analysis can yield novel information and also aid policy makers in the formation of interventions, encouraging alliances among providers as well as planning health system restructuring.
Dynamic Wireless Power Transfer - Grid Impacts Analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Markel, Tony; Meintz, Andrew; Gonder, Jeff
2015-12-04
This presentation discusses the current status of analysis of the electricity grid impacts of a dynamic wireless power transfer system deployed to the Atlanta region on select high traffic roadway segments.
NASA Astrophysics Data System (ADS)
Treffeisen, Renate; Grosfeld, Klaus; Kuhlmann, Franziska
2017-12-01
Knowledge transfer and dialogue processes in the field of climate science have captured intensive attention in recent years as being an important part of research activities. Therefore, the demand and pressure to develop a set of indicators for the evaluation of different activities in this field have increased, too. Research institutes are being asked more and more to build up structures in order to map these activities and, thus, are obliged to demonstrate the success of these efforts. This paper aims to serve as an input to stimulate further reflection on the field of evaluation of knowledge transfer and dialogue processes in the context of climate sciences. The work performed in this paper is embedded in the efforts of the German Helmholtz Association in the research field of earth and environment and is driven by the need to apply suitable indicators for knowledge transfer and dialogue processes in climate research center evaluations. We carry out a comparative analysis of three long-term activities and derive a set of indicators for measuring their output and outcome by balancing the wide diversity and range of activity contents as well as the different tools to realize them. The case examples are based on activities which are part of the regional Helmholtz Climate Initiative Regional Climate Change
(REKLIM) and the Climate Office for Polar Regions and Sea Level Rise at the Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research. Both institutional units have been working on a wide range of different knowledge transfer and dialogue processes since 2008/2009. We demonstrate that indicators for the evaluation must be based on the unique objectives of the individual activities and the framework they are embedded in (e.g., research foci which provide the background for the performed knowledge transfer and dialogue processes) but can partly be classified in a principle two-dimensional scheme. This scheme might serve as a usable basis for climate research center evaluation in the future. It, furthermore, underlines the need for further development of proper mechanisms to evaluate scientific centers, in particular with regard to knowledge transfer and dialogue processes.
NASA Astrophysics Data System (ADS)
Karnes, John J.; Benjamin, Ilan
2018-01-01
Molecular dynamics simulations are used to study the dissolution of water into an adjacent, immiscible organic liquid phase. Equilibrium thermodynamic and structural properties are calculated during the transfer of water molecule(s) across the interface using umbrella sampling. The net free energy of transfer agrees reasonably well with experimental solubility values. We find that water molecules "prefer" to transfer into the adjacent phase one-at-a-time, without co-transfer of the hydration shell, as in the case of evaporation. To study the dynamics and mechanism of transfer of water to liquid nitrobenzene, we collected over 400 independent dissolution events. Analysis of these trajectories suggests that the transfer of water is facilitated by interfacial protrusions of the water phase into the organic phase, where one water molecule at the tip of the protrusion enters the organic phase by the breakup of a single hydrogen bond.
The study of electrochemical cell taught by problem-based learning
NASA Astrophysics Data System (ADS)
Srichaitung, Paisan
2018-01-01
According to the teaching activity of Chemistry, researcher found that students were not able to seek self knowledge even applied knowledge to their everyday life. Therefore, the researcher is interested in creating an activity to have students constructed their knowledge, science process skills, and can apply knowledge in their everyday life. The researcher presented form of teaching activity of electrochemical cell by using problem-based learning for Mathayom five students of Thai Christian School. The teaching activity focused on electron transfer in galvanic cell. In this activity, the researcher assigned students to design the electron transfer in galvanic cell using any solution that could light up the bulb. Then students were separated into a group of two, which were total seven groups. Each group of students searched the information about the electron transfer in galvanic cell from books, internet, or other sources of information. After students received concepts, or knowledge they searched for, Students designed and did the experiment. Finally, the students in each groups had twenty minutes to give a presentation in front of the classroom about the electron transfer in galvanic using any solution to light up the bulb with showing the experiment, and five minutes to answer their classmates' questions. Giving the presentation took four periods with total seven groups. After students finished their presentation, the researcher had students discussed and summarized the teaching activity's main idea of electron transfer in galvanic. Then, researcher observed students' behavior in each group found that 85.7 percentages of total students developed science process skills, and transferred their knowledge through presentation completely. When students done the post test, the researcher found that 92.85 percentages of total students were able to explain the concept of galvanic cell, described the preparation and the selection of experimental equipment. Furthermore, students constructed their skills, scientific process, and seek self knowledge which made them seek the choices to solve problems variously. This Research using problem-based learning can be applied to teaching activity in other subjects.
2003-01-01
media factors affecting: • Shared Understanding – explicit and operational knowledge • Decision-Making – what information format best helps decision...Passing the Bubble: Cognitive Efficiency of Augmented Video for Collaborative Transfer of Situational Understanding Collaboration and Knowledge ...operational knowledge ? • Informed Decision-Making – what information format is best to pass the bubble to a decision-maker 1/14/2003 ONR David Kirsh
Energy transfer dynamics in Light-Harvesting Dendrimers
NASA Astrophysics Data System (ADS)
Melinger, Joseph S.; McMorrow, Dale; Kleiman, Valeria D.
2002-03-01
We explore energy transfer dynamics in light-harvesting phenylacetylene symmetric and asymmetric dendrimers. Femtosecond pump-probe spectroscopy is used to probe the ultrafast dynamics of electronic excitations in these dendrimers. The backbone of the macromolecule consists of branches of increasing conjugation length, creating an energy gradient, which funnels energy to an accepting perylene trap. In the case of the symmetric dendrimer (nanostar), the energy transfer efficiency is known to approach nearly unity, although the nature and timescale of the energy transfer process is still unknown. For the asymmetric dendrimers, energy transfer efficiencies are very high, with the possibility of more complex transfer processes. We experimentally monitor the transport of excitons through the light-harvesting dendrimer. The transients show a number of components, with timescales ranging from <300fs to several tens of picoseconds, revealing the complex photophysics taking place in these macromolecules. We interpret our results in terms of the Förster mechanism in which energy transfer occurs through dipole-dipole interactions.
NASA Astrophysics Data System (ADS)
Watanuki, Keiichi; Kojima, Kazuyuki
The environment in which Japanese industry has achieved great respect is changing tremendously due to the globalization of world economies, while Asian countries are undergoing economic and technical development as well as benefiting from the advances in information technology. For example, in the design of custom-made casting products, a designer who lacks knowledge of casting may not be able to produce a good design. In order to obtain a good design and manufacturing result, it is necessary to equip the designer and manufacturer with a support system related to casting design, or a so-called knowledge transfer and creation system. This paper proposes a new virtual reality based knowledge acquisition and job training system for casting design, which is composed of the explicit and tacit knowledge transfer systems using synchronized multimedia and the knowledge internalization system using portable virtual environment. In our proposed system, the education content is displayed in the immersive virtual environment, whereby a trainee may experience work in the virtual site operation. Provided that the trainee has gained explicit and tacit knowledge of casting through the multimedia-based knowledge transfer system, the immersive virtual environment catalyzes the internalization of knowledge and also enables the trainee to gain tacit knowledge before undergoing on-the-job training at a real-time operation site.
Becker, Torben K; Skiba, James F; Sozener, Cemal B
2015-06-01
Patient transfers among medical facilities are high-risk situations. Despite this, there is very little training of physicians regarding the medical and legal aspects of transport medicine. To examine the effects of a one hour, educational intervention on Emergency Medicine (EM) residents' and Critical Care (CC) fellows' knowledge regarding the medical and legal aspects of interfacility patient transfers. Prior to the intervention, physician knowledge regarding 12 key concepts in patient transfer was assessed using a pre-test instrument. A one hour, interactive, educational session followed immediately thereafter. Following the intervention, a post-intervention test was given between two and four weeks after delivery. Participants were also asked to describe any prior transportation-medicine-related education, their opinions as they relate to the relevance of the topic, and their comfort levels with patient transfers before and after the intervention. Only a minority of participants had received any formal training in patient transfers prior to the intervention, despite dealing with patient transfers on a frequent, often daily, basis. Both groups improved in several categories on the post-intervention test. They reported improved comfort levels with the medicolegal aspects of interfacility patient transfers after the intervention and felt well-prepared to manage transfers in their daily practice. A one hour, educational intervention objectively increased EM and CC physician trainees' understanding of some of the medicolegal aspects of interfacility patient transfers. The study demonstrated a lack of previous training on this important topic and improved levels of comfort with transfers after study participation.
Joiner, Wilsaan M.; Brayanov, Jordan B.
2013-01-01
The way that a motor adaptation is trained, for example, the manner in which it is introduced or the duration of the training period, can influence its internal representation. However, recent studies examining the gradual versus abrupt introduction of a novel environment have produced conflicting results. Here we examined how these effects determine the effector specificity of motor adaptation during visually guided reaching. After adaptation to velocity-dependent dynamics in the right arm, we estimated the amount of adaptation transferred to the left arm, using error-clamp measurement trials to directly measure changes in learned dynamics. We found that a small but significant amount of generalization to the untrained arm occurs under three different training schedules: a short-duration (15 trials) abrupt presentation, a long-duration (160 trials) abrupt presentation, and a long-duration gradual presentation of the novel dynamic environment. Remarkably, we found essentially no difference between the amount of interlimb generalization when comparing these schedules, with 9–12% transfer of the trained adaptation for all three. However, the duration of training had a pronounced effect on the stability of the interlimb transfer: The transfer elicited from short-duration training decayed rapidly, whereas the transfer from both long-duration training schedules was considerably more persistent (<50% vs. >90% retention over the first 20 trials). These results indicate that the amount of interlimb transfer is similar for gradual versus abrupt training and that interlimb transfer of learned dynamics can occur after even a brief training period but longer training is required for an enduring effect. PMID:23719204
Joiner, Wilsaan M; Brayanov, Jordan B; Smith, Maurice A
2013-08-01
The way that a motor adaptation is trained, for example, the manner in which it is introduced or the duration of the training period, can influence its internal representation. However, recent studies examining the gradual versus abrupt introduction of a novel environment have produced conflicting results. Here we examined how these effects determine the effector specificity of motor adaptation during visually guided reaching. After adaptation to velocity-dependent dynamics in the right arm, we estimated the amount of adaptation transferred to the left arm, using error-clamp measurement trials to directly measure changes in learned dynamics. We found that a small but significant amount of generalization to the untrained arm occurs under three different training schedules: a short-duration (15 trials) abrupt presentation, a long-duration (160 trials) abrupt presentation, and a long-duration gradual presentation of the novel dynamic environment. Remarkably, we found essentially no difference between the amount of interlimb generalization when comparing these schedules, with 9-12% transfer of the trained adaptation for all three. However, the duration of training had a pronounced effect on the stability of the interlimb transfer: The transfer elicited from short-duration training decayed rapidly, whereas the transfer from both long-duration training schedules was considerably more persistent (<50% vs. >90% retention over the first 20 trials). These results indicate that the amount of interlimb transfer is similar for gradual versus abrupt training and that interlimb transfer of learned dynamics can occur after even a brief training period but longer training is required for an enduring effect.
Succession Planning and Knowledge Transfer in Higher Education
ERIC Educational Resources Information Center
Grossman, Connie S.
2014-01-01
A leadership gap is occurring as the result of Baby Boomer retirements coupled with the lack of academic succession planning. Transferring organizational knowledge from leadership to successors is a challenging task during leadership change. Succession planning processes are designed for present and future organizational needs by facilitating…
Knowledge Transfer Partnerships and the Entrepreneurial University
ERIC Educational Resources Information Center
Wynn, Martin; Jones, Peter
2017-01-01
This article outlines one way in which less research-intensive universities can contribute to entrepreneurship by examining the achievements of several Knowledge Transfer Partnerships (KTPs) in the University of Gloucestershire. The article adopts a qualitative case study approach: four case studies of KTPs at, respectively, Beacons Business…
Knowledge translation of research findings
2012-01-01
Background One of the most consistent findings from clinical and health services research is the failure to translate research into practice and policy. As a result of these evidence-practice and policy gaps, patients fail to benefit optimally from advances in healthcare and are exposed to unnecessary risks of iatrogenic harms, and healthcare systems are exposed to unnecessary expenditure resulting in significant opportunity costs. Over the last decade, there has been increasing international policy and research attention on how to reduce the evidence-practice and policy gap. In this paper, we summarise the current concepts and evidence to guide knowledge translation activities, defined as T2 research (the translation of new clinical knowledge into improved health). We structure the article around five key questions: what should be transferred; to whom should research knowledge be transferred; by whom should research knowledge be transferred; how should research knowledge be transferred; and, with what effect should research knowledge be transferred? Discussion We suggest that the basic unit of knowledge translation should usually be up-to-date systematic reviews or other syntheses of research findings. Knowledge translators need to identify the key messages for different target audiences and to fashion these in language and knowledge translation products that are easily assimilated by different audiences. The relative importance of knowledge translation to different target audiences will vary by the type of research and appropriate endpoints of knowledge translation may vary across different stakeholder groups. There are a large number of planned knowledge translation models, derived from different disciplinary, contextual (i.e., setting), and target audience viewpoints. Most of these suggest that planned knowledge translation for healthcare professionals and consumers is more likely to be successful if the choice of knowledge translation strategy is informed by an assessment of the likely barriers and facilitators. Although our evidence on the likely effectiveness of different strategies to overcome specific barriers remains incomplete, there is a range of informative systematic reviews of interventions aimed at healthcare professionals and consumers (i.e., patients, family members, and informal carers) and of factors important to research use by policy makers. Summary There is a substantial (if incomplete) evidence base to guide choice of knowledge translation activities targeting healthcare professionals and consumers. The evidence base on the effects of different knowledge translation approaches targeting healthcare policy makers and senior managers is much weaker but there are a profusion of innovative approaches that warrant further evaluation. PMID:22651257
Hacisuleyman, Aysima; Erman, Burak
2017-06-01
A fast and approximate method of generating allosteric communication landscapes in proteins is presented by using Schreiber's entropy transfer concept in combination with the Gaussian Network Model of proteins. Predictions of the model and the allosteric communication landscapes generated show that information transfer in proteins does not necessarily take place along a single path, but an ensemble of pathways is possible. The model emphasizes that knowledge of entropy only is not sufficient for determining allosteric communication and additional information based on time delayed correlations should be introduced, which leads to the presence of causality in proteins. The model provides a simple tool for mapping entropy sink-source relations into pairs of residues. By this approach, residues that should be manipulated to control protein activity may be determined. This should be of great importance for allosteric drug design and for understanding the effects of mutations on function. The model is applied to determine allosteric communication in three proteins, Ubiquitin, Pyruvate Kinase, and the PDZ domain. Predictions are in agreement with molecular dynamics simulations and experimental evidence. Proteins 2017; 85:1056-1064. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.
Dissolving Hydroxyolite: A DNA Molecule into Its Hydroxyapatite Mold.
Bertran, Oscar; Revilla-López, Guillermo; Casanovas, Jordi; Del Valle, Luis J; Turon, Pau; Puiggalí, Jordi; Alemán, Carlos
2016-05-04
In spite of the clinical importance of hydroxyapatite (HAp), the mechanism that controls its dissolution in acidic environments remains unclear. Knowledge of such a process is highly desirable to provide better understanding of different pathologies, as for example osteoporosis, and of the HAp potential as vehicle for gene delivery to replace damaged DNA. In this work, the mechanism of dissolution in acid conditions of HAp nanoparticles encapsulating double-stranded DNA has been investigated at the atomistic level using computer simulations. For this purpose, four consecutive (multi-step) molecular dynamics simulations, involving different temperatures and proton transfer processes, have been carried out. Results are consistent with a polynuclear decalcification mechanism in which proton transfer processes, from the surface to the internal regions of the particle, play a crucial role. In addition, the DNA remains protected by the mineral mold and transferred proton from both temperature and chemicals. These results, which indicate that biomineralization imparts very effective protection to DNA, also have important implications in other biomedical fields, as for example in the design of artificial bones or in the fight against osteoporosis by promoting the fixation of Ca(2+) ions. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Swept shock/boundary layer interaction experiments in support of CFD code validation
NASA Technical Reports Server (NTRS)
Settles, G. S.; Lee, Y.
1992-01-01
Research on the topic of shock wave/turbulent boundary-layer interaction was carried out during the past three years at the Penn State Gas Dynamics Laboratory. This report describes the experimental research program which provides basic knowledge and establishes new data on heat transfer in swept shock wave/boundary-layer interactions. An equilibrium turbulent boundary-layer on a flat plate is subjected to impingement by swept planar shock waves generated by a sharp fin. Five different interactions with fin angle ranging from 10 deg to 20 deg at freestream Mach numbers of 3.0 and 4.0 produce a variety of interaction strengths from weak to very strong. A foil heater generates a uniform heat flux over the flat plate surface, and miniature thin-film-resistance sensors mounted on it are used to measure the local surface temperature. The heat convection equation is then solved for the heat transfer distribution within an interaction, yielding a total uncertainty of about +/- 10 percent. These experimental data are compared with the results of numerical Navier-Stokes solutions which employ a k-epsilon turbulence model. Finally, a simplified form of the peak heat transfer correlation for fin interactions is suggested.
Dynamic response of a modified water tank exposed to concentrated solar energy
NASA Astrophysics Data System (ADS)
Alhamdo, M. H.; Alkhakani, A. J.
2017-08-01
Power generation by using concentrated solar thermal energy on liquid enclosures is one of the most promising renewable energy technologies. In this work, a developed liquid enclosure fitted with various number and configurations of horizontal metal rings have been analyzed, fabricated and tested. The influence of adding metal rings arrangement is investigated for its potential to enhance radial heat conduction to the center-line of the enclosure from the side-walls. Experiments were carried out for fluid in both static and dynamic modes of operation inside the enclosure that subjected to high heat flux. A developed two-dimensional CFD model to predict the transient flow and thermal fields within liquid enclosure subjected to heat flux has been developed and tested. The developed numerical model takes into consideration energy transport between the liquid inside enclosure and the solid material of the enclosure. The numerical simulations have been compared with experimental measurement. The computational code has been found in a good level of agreement with the experimental data except for liquid at the peak part of the enclosure. The results indicate that adding metal rings produce significant impact on the transient temperature difference inside enclosure during both static and dynamic modes. The six-ring model is found to be more effective for enhancing radial heat transfer than other three models that have been tested. The in-line arrangement is found to provide better thermal effect as compared to the staggered rings. Two new correlations for natural heat transfer inside liquid enclosures subjected to high heat flux have been formulated (one for no-ring model and the other for six-ring model). The natural Nusselt number is found to be around a constant value for Rayleigh number less than (5 X 108). The recommended use of metal rings inside liquid enclosures subjected to heat flux, and the predicted Nusselt number correlation, will add to local knowledge a significant mean to gain more heat in large scale concentrated solar power plants. Two new correlations for natural heat transfer inside liquid enclosures subjected to high heat flux have been formulated (one for no-ring model and the other for six-ring model). The natural Nusselt number is found to be around a constant value for Rayleigh number less than (5 X 108). The recommended use of metal rings inside liquid enclosures subjected to heat flux, and the predicted Nusselt number correlation, will add to local knowledge a significant mean to gain more heat in large scale concentrated solar power plants.
Missing Modality Transfer Learning via Latent Low-Rank Constraint.
Ding, Zhengming; Shao, Ming; Fu, Yun
2015-11-01
Transfer learning is usually exploited to leverage previously well-learned source domain for evaluating the unknown target domain; however, it may fail if no target data are available in the training stage. This problem arises when the data are multi-modal. For example, the target domain is in one modality, while the source domain is in another. To overcome this, we first borrow an auxiliary database with complete modalities, then consider knowledge transfer across databases and across modalities within databases simultaneously in a unified framework. The contributions are threefold: 1) a latent factor is introduced to uncover the underlying structure of the missing modality from the known data; 2) transfer learning in two directions allows the data alignment between both modalities and databases, giving rise to a very promising recovery; and 3) an efficient solution with theoretical guarantees to the proposed latent low-rank transfer learning algorithm. Comprehensive experiments on multi-modal knowledge transfer with missing target modality verify that our method can successfully inherit knowledge from both auxiliary database and source modality, and therefore significantly improve the recognition performance even when test modality is inaccessible in the training stage.
Yildirim, Ilker; Jacobs, Robert A
2015-06-01
If a person is trained to recognize or categorize objects or events using one sensory modality, the person can often recognize or categorize those same (or similar) objects and events via a novel modality. This phenomenon is an instance of cross-modal transfer of knowledge. Here, we study the Multisensory Hypothesis which states that people extract the intrinsic, modality-independent properties of objects and events, and represent these properties in multisensory representations. These representations underlie cross-modal transfer of knowledge. We conducted an experiment evaluating whether people transfer sequence category knowledge across auditory and visual domains. Our experimental data clearly indicate that we do. We also developed a computational model accounting for our experimental results. Consistent with the probabilistic language of thought approach to cognitive modeling, our model formalizes multisensory representations as symbolic "computer programs" and uses Bayesian inference to learn these representations. Because the model demonstrates how the acquisition and use of amodal, multisensory representations can underlie cross-modal transfer of knowledge, and because the model accounts for subjects' experimental performances, our work lends credence to the Multisensory Hypothesis. Overall, our work suggests that people automatically extract and represent objects' and events' intrinsic properties, and use these properties to process and understand the same (and similar) objects and events when they are perceived through novel sensory modalities.
Single-Molecule Interfacial Electron Transfer
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu, H. Peter
This project is focused on the use of single-molecule high spatial and temporal resolved techniques to study molecular dynamics in condensed phase and at interfaces, especially, the complex reaction dynamics associated with electron and energy transfer rate processes. The complexity and inhomogeneity of the interfacial ET dynamics often present a major challenge for a molecular level comprehension of the intrinsically complex systems, which calls for both higher spatial and temporal resolutions at ultimate single-molecule and single-particle sensitivities. Combined single-molecule spectroscopy and electrochemical atomic force microscopy approaches are unique for heterogeneous and complex interfacial electron transfer systems because the static andmore » dynamic inhomogeneities can be identified and characterized by studying one molecule at a specific nanoscale surface site at a time. The goal of our project is to integrate and apply these spectroscopic imaging and topographic scanning techniques to measure the energy flow and electron flow between molecules and substrate surfaces as a function of surface site geometry and molecular structure. We have been primarily focusing on studying interfacial electron transfer under ambient condition and electrolyte solution involving both single crystal and colloidal TiO 2 and related substrates. The resulting molecular level understanding of the fundamental interfacial electron transfer processes will be important for developing efficient light harvesting systems and broadly applicable to problems in fundamental chemistry and physics. We have made significant advancement on deciphering the underlying mechanism of the complex and inhomogeneous interfacial electron transfer dynamics in dyesensitized TiO 2 nanoparticle systems that strongly involves with and regulated by molecule-surface interactions. We have studied interfacial electron transfer on TiO 2 nanoparticle surfaces by using ultrafast single-molecule spectroscopy and electrochemical AFM metal tip scanning microscopy, focusing on understanding the interfacial electron transfer dynamics at specific nanoscale electron transfer sites with high-spatially and temporally resolved topographic-and-spectroscopic characterization at individual molecule basis, characterizing single-molecule rate processes, reaction driving force, and molecule-substrate electronic coupling. One of the most significant characteristics of our new approach is that we are able to interrogate the complex interfacial electron transfer dynamics by actively pin-point energetic manipulation of the surface interaction and electronic couplings, beyond the conventional excitation and observation.« less
Serotonergic Psychedelics Temporarily Modify Information Transfer in Humans
Alonso, Joan Francesc; Romero, Sergio; Mañanas, Miquel Àngel
2015-01-01
Background: Psychedelics induce intense modifications in the sensorium, the sense of “self,” and the experience of reality. Despite advances in our understanding of the molecular and cellular level mechanisms of these drugs, knowledge of their actions on global brain dynamics is still incomplete. Recent imaging studies have found changes in functional coupling between frontal and parietal brain structures, suggesting a modification in information flow between brain regions during acute effects. Methods: Here we assessed the psychedelic-induced changes in directionality of information flow during the acute effects of a psychedelic in humans. We measured modifications in connectivity of brain oscillations using transfer entropy, a nonlinear measure of directed functional connectivity based on information theory. Ten healthy male volunteers with prior experience with psychedelics participated in 2 experimental sessions. They received a placebo or a dose of ayahuasca, a psychedelic preparation containing the serotonergic 5-HT2A agonist N,N-dimethyltryptamine. Results: The analysis showed significant changes in the coupling of brain oscillations between anterior and posterior recording sites. Transfer entropy analysis showed that frontal sources decreased their influence over central, parietal, and occipital sites. Conversely, sources in posterior locations increased their influence over signals measured at anterior locations. Exploratory correlations found that anterior-to-posterior transfer entropy decreases were correlated with the intensity of subjective effects, while the imbalance between anterior-to-posterior and posterior-to-anterior transfer entropy correlated with the degree of incapacitation experienced. Conclusions: These results suggest that psychedelics induce a temporary disruption of neural hierarchies by reducing top-down control and increasing bottom-up information transfer in the human brain. PMID:25820842
Thürer, Benjamin; Focke, Anne; Stein, Thorsten
2015-01-01
Intermanual transfer, i.e., generalization of motor learning across hands, is a well-accepted phenomenon of motor learning. Yet, there are open questions regarding the characteristics of this transfer, particularly the intermanual transfer of dynamic learning. In this study, we investigated intermanual transfer in a force field adaptation task concerning the direction and the coordinate frame of transfer as well as the influence of a 24-h consolidation period on the transfer. We tested 48 healthy human subjects for transfer from dominant to nondominant hand, and vice versa. We considered two features of transfer. First, we examined transfer to the untrained hand using force channel trials that suppress error feedback and learning mechanisms to assess intermanual transfer in the form of a practice-dependent bias. Second, we considered transfer by exposing the subjects to the force field with the untrained hand to check for faster learning of the dynamics (interlimb savings). Half of the subjects were tested for transfer immediately after adaptation, whereas the other half were tested after a 24-h consolidation period. Our results showed intermanual transfer both from dominant to nondominant hand and vice versa in extrinsic coordinates. After the consolidation period, transfer effects were weakened. Moreover, the transfer effects were negligible compared with the subjects' ability to rapidly adapt to the force field condition. We conclude that intermanual transfer is a bidirectional phenomenon that vanishes with time. However, the ability to transfer motor learning seems to play a minor role compared with the rapid adaptation processes. PMID:26424581
NASA Astrophysics Data System (ADS)
Saez, David Adrian; Vöhringer-Martinez, Esteban
2015-10-01
S-Adenosylmethionine (AdoMet) is involved in many biological processes as cofactor in enzymes transferring its sulfonium methyl group to various substrates. Additionally, it is used as drug and nutritional supplement to reduce the pain in osteoarthritis and against depression. Due to the biological relevance of AdoMet it has been part of various computational simulation studies and will also be in the future. However, to our knowledge no rigorous force field parameter development for its simulation in biological systems has been reported. Here, we use electronic structure calculations combined with molecular dynamics simulations in explicit solvent to develop force field parameters compatible with the AMBER99 force field. Additionally, we propose new dynamic Hirshfeld-I atomic charges which are derived from the polarized electron density of AdoMet in aqueous solution to describe its electrostatic interactions in biological systems. The validation of the force field parameters and the atomic charges is performed against experimental interproton NOE distances of AdoMet in aqueous solution and crystal structures of AdoMet in the cavity of three representative proteins.
Transfer of knowledge and skills: some implications for nursing and nurse education.
Lauder, W; Reynolds, W; Angus, N
1999-08-01
The construct of transfer has enormous importance to nursing as it begins to highlight potential problems in the transfer of knowledge and skills from the campus to the clinical area, from one part of the clinical area to another (e.g. surgical to medical), and from community to the clinical area. Thus, any adequate conceptualization of transfer must account for problems of practice-practice transfer as well as theory-practice transfer. These potential problems are the concern of educators, students and managers who have a responsibility for agency nurses and bank nurses who may find themselves in different specialities on a regular basis. Transfer has relevance to a whole raft of other issues ranging from the application of theories to nursing practice, through to the validity of claims that courses which develop intellectual skills prepare nurses for lifelong learning.
Ultrafast Intramolecular Electron and Proton Transfer in Bis(imino)isoindole Derivatives.
Driscoll, Eric; Sorenson, Shayne; Dawlaty, Jahan M
2015-06-04
Concerted motion of electrons and protons in the excited state is pertinent to a wide range of chemical phenomena, including those relevant for solar-to-fuel light harvesting. The excited state dynamics of small proton-bearing molecules are expected to serve as models for better understanding such phenomena. In particular, for designing the next generation of multielectron and multiproton redox catalysts, understanding the dynamics of more than one proton in the excited state is important. Toward this goal, we have measured the ultrafast dynamics of intramolecular excited state proton transfer in a recently synthesized dye with two equivalent transferable protons. We have used a visible ultrafast pump to initiate the proton transfer in the excited state, and have probed the transient absorption of the molecule over a wide bandwidth in the visible range. The measurement shows that the signal which is characteristic of proton transfer emerges within ∼710 fs. To identify whether both protons were transferred in the excited state, we have measured the ultrafast dynamics of a related derivative, where only a single proton was available for transfer. The measured proton transfer time in that molecule was ∼427 fs. The observed dynamics in both cases were reasonably fit with single exponentials. Supported by the ultrafast observations, steady-state fluorescence, and preliminary computations of the relaxed excited states, we argue that the doubly protonated derivative most likely transfers only one of its two protons in the excited state. We have performed calculations of the frontier molecular orbitals in the Franck-Condon region. The calculations show that in both derivatives, the excitation is primarily from the HOMO to LUMO causing a large rearrangement of the electronic charge density immediately after photoexcitation. In particular, charge density is shifted away from the phenolic protons and toward the proton acceptor nitrogens. The proton transfer is hypothesized to occur both due to enhanced acidity of the phenolic proton and enhanced basicity of the nitrogen in the excited state. We hope this study can provide insight for better understanding of the general class of excited state concerted electron-proton dynamics.
Knowledge to Go: A Motivational and Dispositional View of Transfer
ERIC Educational Resources Information Center
Perkins, David N.; Salomon, Gavriel
2012-01-01
We synthesize ideas from the foregoing articles in this special issue and from the broader literature on transfer to explore several themes. In many ordinary life circumstances, transfer proceeds easily, but formal learning often shows much less transfer than educators would like, making failure to transfer a focus of investigation. Transfer, like…
Intergenerational Learning and Knowledge Transfer--Challenges and Opportunities
ERIC Educational Resources Information Center
Rupcic, Nataša
2018-01-01
Purpose: The purpose of this paper is to highlight challenges and opportunities that surround the process of intergenerational learning and knowledge transfer. Several options in this regard have been discussed from the managerial and employee perspective. Design/methodology/approach: The systems approach has been implemented to identify options…
The Design of Computerized Practice Fields for Problem Solving and Contextualized Transfer
ERIC Educational Resources Information Center
Riedel, Jens; Fitzgerald, Gail; Leven, Franz; Toenshoff, Burkhard
2003-01-01
Current theories of learning emphasize the importance of learner-centered, active, authentic, environments for meaningful knowledge construction. From this perspective, computerized case-based learning systems afford practice fields for learners to build domain knowledge and problem-solving skills and to support contextualized transfer of…
The Role of Culture on Knowledge Transfer: The Case of the Multinational Corporation
ERIC Educational Resources Information Center
Lucas, Leyland M.
2006-01-01
Purpose: This paper aims to look at the issue of culture's role in knowledge transfer within multinational corporations (MNCs). Studies of MNCs have hinted at the importance of culture to the performance of subsidiaries. Using Hofstede's cultural dimensions of power distance, individualism/collectivism, uncertainty avoidance, and…
Application Exercises Improve Transfer of Statistical Knowledge in Real-World Situations
ERIC Educational Resources Information Center
Daniel, Frances; Braasch, Jason L. G.
2013-01-01
The present research investigated whether real-world application exercises promoted students' abilities to spontaneously transfer statistical knowledge and to recognize the use of statistics in real-world contexts. Over the course of a semester of psychological statistics, two classes completed multiple application exercises designed to mimic…
Supporting the M-Learning Based Knowledge Transfer in University Education and Corporate Sector
ERIC Educational Resources Information Center
Benedek, András; Molnár, György
2014-01-01
The evolution of today's connective forms of teaching and learning draws attention to expansion of "space" in which teaching and learning moments: engaging the attention, knowledge transfer, acquisition, demonstration, experience, experiment research and practice, conclusions are organized around a more free method. Due to these…
Characteristics of Context for Instructional Design
ERIC Educational Resources Information Center
Hansen, Brett E.
2010-01-01
The fast-paced and continual change experienced in the workplace requires graduates to possess knowledge that can immediately transfer to their chosen profession so that they can quickly become productive and successful. Learning in context is known to have positive effects on learning and facilitate the transfer of knowledge from learning…
Supporting Students' Knowledge Transfer in Modeling Activities
ERIC Educational Resources Information Center
Piksööt, Jaanika; Sarapuu, Tago
2014-01-01
This study investigates ways to enhance secondary school students' knowledge transfer in complex science domains by implementing question prompts. Two samples of students applied two web-based models to study molecular genetics--the model of genetic code (n = 258) and translation (n = 245). For each model, the samples were randomly divided into…
Transfer of Learning across Courses in an MBA Curriculum: A Managerial Finance Case Study
ERIC Educational Resources Information Center
Stretcher, Robert; Hynes, Geraldine E.; Maniam, Bala
2010-01-01
Business degree programs typically include a variety of required courses targeting analytical skills, general knowledge, and communication competencies. Integration of these learning outcomes is crucial for students' effective professional activities, yet little is known about cross-disciplinary transfer of specific knowledge, skills, and…
Critical Success Factors for Knowledge Transfer Collaborations between University and Industry
ERIC Educational Resources Information Center
Schofield, Tatiana
2013-01-01
In a fast moving business environment university-industry collaborations play a critical role in contributing to national economies and furthering a competitive advantage. Knowledge transfer from university to industry is supported by national governments as part of their innovation, national growth and competitiveness agenda. A…
Policy Transfer via Markov Logic Networks
NASA Astrophysics Data System (ADS)
Torrey, Lisa; Shavlik, Jude
We propose using a statistical-relational model, the Markov Logic Network, for knowledge transfer in reinforcement learning. Our goal is to extract relational knowledge from a source task and use it to speed up learning in a related target task. We show that Markov Logic Networks are effective models for capturing both source-task Q-functions and source-task policies. We apply them via demonstration, which involves using them for decision making in an initial stage of the target task before continuing to learn. Through experiments in the RoboCup simulated-soccer domain, we show that transfer via Markov Logic Networks can significantly improve early performance in complex tasks, and that transferring policies is more effective than transferring Q-functions.
Spatio-temporal correlations in models of collective motion ruled by different dynamical laws.
Cavagna, Andrea; Conti, Daniele; Giardina, Irene; Grigera, Tomas S; Melillo, Stefania; Viale, Massimiliano
2016-11-15
Information transfer is an essential factor in determining the robustness of biological systems with distributed control. The most direct way to study the mechanisms ruling information transfer is to experimentally observe the propagation across the system of a signal triggered by some perturbation. However, this method may be inefficient for experiments in the field, as the possibilities to perturb the system are limited and empirical observations must rely on natural events. An alternative approach is to use spatio-temporal correlations to probe the information transfer mechanism directly from the spontaneous fluctuations of the system, without the need to have an actual propagating signal on record. Here we test this method on models of collective behaviour in their deeply ordered phase by using ground truth data provided by numerical simulations in three dimensions. We compare two models characterized by very different dynamical equations and information transfer mechanisms: the classic Vicsek model, describing an overdamped noninertial dynamics and the inertial spin model, characterized by an underdamped inertial dynamics. By using dynamic finite-size scaling, we show that spatio-temporal correlations are able to distinguish unambiguously the diffusive information transfer mechanism of the Vicsek model from the linear mechanism of the inertial spin model.
Supporting Knowledge Transfer in IS Deployment Projects
NASA Astrophysics Data System (ADS)
Schönström, Mikael
To deploy new information systems is an expensive and complex task, and does seldom result in successful usage where the system adds strategic value to the firm (e.g. Sharma et al. 2003). It has been argued that innovation diffusion is a knowledge integration problem (Newell et al. 2000). Knowledge about business processes, deployment processes, information systems and technology are needed in a large-scale deployment of a corporate IS. These deployments can therefore to a large extent be argued to be a knowledge management (KM) problem. An effective deployment requires that knowledge about the system is effectively transferred to the target organization (Ko et al. 2005).
Low-Thrust Trajectory Optimization with Simplified SQP Algorithm
NASA Technical Reports Server (NTRS)
Parrish, Nathan L.; Scheeres, Daniel J.
2017-01-01
The problem of low-thrust trajectory optimization in highly perturbed dynamics is a stressing case for many optimization tools. Highly nonlinear dynamics and continuous thrust are each, separately, non-trivial problems in the field of optimal control, and when combined, the problem is even more difficult. This paper de-scribes a fast, robust method to design a trajectory in the CRTBP (circular restricted three body problem), beginning with no or very little knowledge of the system. The approach is inspired by the SQP (sequential quadratic programming) algorithm, in which a general nonlinear programming problem is solved via a sequence of quadratic problems. A few key simplifications make the algorithm presented fast and robust to initial guess: a quadratic cost function, neglecting the line search step when the solution is known to be far away, judicious use of end-point constraints, and mesh refinement on multiple shooting with fixed-step integration.In comparison to the traditional approach of plugging the problem into a “black-box” NLP solver, the methods shown converge even when given no knowledge of the solution at all. It was found that the only piece of information that the user needs to provide is a rough guess for the time of flight, as the transfer time guess will dictate which set of local solutions the algorithm could converge on. This robustness to initial guess is a compelling feature, as three-body orbit transfers are challenging to design with intuition alone. Of course, if a high-quality initial guess is available, the methods shown are still valid.We have shown that endpoints can be efficiently constrained to lie on 3-body repeating orbits, and that time of flight can be optimized as well. When optimizing the endpoints, we must make a trade between converging quickly on sub-optimal endpoints or converging more slowly on end-points that are arbitrarily close to optimal. It is easy for the mission design engineer to adjust this trade based on the problem at hand.The biggest limitation to the algorithm at this point is that multi-revolution transfers (greater than 2 revolutions) do not work nearly as well. This restriction comes in because the relationship between node 1 and node N becomes increasingly nonlinear as the angular distance grows. Trans-fers with more than about 1.5 complete revolutions generally require the line search to improve convergence. Future work includes: Comparison of this algorithm with other established tools; improvements to how multiple-revolution transfers are handled; parallelization of the Jacobian computation; in-creased efficiency for the line search; and optimization of many more trajectories between a variety of 3-body orbits.
ERIC Educational Resources Information Center
Kaminski, Karen; Foley, Jeffrey M.; Kaiser, Leann M. R.
2013-01-01
Throughout the chapters in this issue, the authors have cited various definitions for learning transfer. For educators, in its simplest form, transfer of learning occurs when students put to practical use the knowledge and skills they gained in the classroom (near transfer). Chapter 1 defines near transfer and then goes into detail on the levels…
Interpretations of the Patient-Therapist Relationship in Brief Dynamic Psychotherapy
AMLO, SVEIN; ENGELSTAD, VIBEKE; FOSSUM, ARNE; SØRLIE, TORE; HØGLEND, PER; HEYERDAHL, OSCAR; SØRBYE, ØYSTEIN
1993-01-01
The authors examined whether persistent analysis of the patient-therapist relationship in brief dynamic psychotherapy favorably affects long-term dynamic change in patients initially deemed suitable for such treatment. As in common practice, 22 highly suitable patients were given a high number of transference interpretations per session. A comparison group of 21 patients with lower suitability received the same treatment, but transference interpretations were withheld. Statistical adjustment for the deliberate nonequivalence in pretreatment suitability indicated a significant negative effect of high numbers of transference interpretations on long-term dynamic changes. Demographic variables, DSM-III diagnoses, additional treatment, life events in the follow-up years, or therapist effects did not explain or obscure the findings. PMID:22700155
Hurtubise, Karen; Rivard, Lisa; Héguy, Léa; Berbari, Jade; Camden, Chantal
2016-01-01
Knowledge transfer in pediatric rehabilitation is challenging and requires active, multifaceted strategies. The use of knowledge brokers (KBs) is one such strategy noted to promote clinician behavior change. The success of using KBs to transfer knowledge relies on their ability to adapt to ever-changing clinical contexts. In addition, with the rapid growth of online platforms as knowledge transfer forums, KBs must become effective in virtual environments. Although the role of KBs has been studied in various clinical contexts, their emerging role in specific online environments designed to support evidence-based behavior change has not yet been described. Our objective is to describe the roles of, and strategies used by, four KBs involved in a virtual community of practice to guide and inform future online KB interventions. A descriptive design guided this study and a thematic content analysis process was used to analyze online KB postings. The Promoting Action on Research in Health Sciences knowledge transfer framework and online andragogical learning theories assisted in the coding. A thematic map was created illustrating the links between KBs' strategies and emerging roles in the virtual environment. We analyzed 95 posts and identified three roles: 1) context architect: promoting a respectful learning environment, 2) knowledge sharing promoter: building capacity, and 3) linkage creator: connecting research-to-practice. Strategies used by KBs reflected invitational, constructivism, and connectivism approaches, with roles and strategies changing over time. This study increases our understanding of the actions of KBs in virtual contexts to foster uptake of research evidence in pediatric physiotherapy. Our results provide valuable information about the knowledge and skills required by individuals to fulfill this role in virtual environments.
García-Alonso, Carlos; Pérez-Naranjo, Leonor
2009-01-01
Introduction Knowledge management, based on information transfer between experts and analysts, is crucial for the validity and usability of data envelopment analysis (DEA). Aim To design and develop a methodology: i) to assess technical efficiency of small health areas (SHA) in an uncertainty environment, and ii) to transfer information between experts and operational models, in both directions, for improving expert’s knowledge. Method A procedure derived from knowledge discovery from data (KDD) is used to select, interpret and weigh DEA inputs and outputs. Based on KDD results, an expert-driven Monte-Carlo DEA model has been designed to assess the technical efficiency of SHA in Andalusia. Results In terms of probability, SHA 29 is the most efficient being, on the contrary, SHA 22 very inefficient. 73% of analysed SHA have a probability of being efficient (Pe) >0.9 and 18% <0.5. Conclusions Expert knowledge is necessary to design and validate any operational model. KDD techniques make the transfer of information from experts to any operational model easy and results obtained from the latter improve expert’s knowledge.
Malti, Tina; Beelmann, Andreas; Noam, Gil G; Sommer, Simon
2018-04-01
In this article, we introduce the special issue entitled Innovation and Integrity in Intervention Science. Its focus is on essential problems and prospects for intervention research examining two related topics, i.e., methodological issues and research integrity, and challenges in the transfer of research knowledge into practice and policy. The main aims are to identify how to advance methodology in order to improve research quality, examine scientific integrity in the field of intervention science, and discuss future steps to enhance the transfer of knowledge about evidence-based intervention principles into sustained practice, routine activities, and policy decisions. Themes of the special issue are twofold. The first includes questions about research methodology in intervention science, both in terms of research design and methods, as well as data analyses and the reporting of findings. Second, the issue tackles questions surrounding the types of knowledge translation frameworks that might be beneficial to mobilize the transfer of research-based knowledge into practice and public policies. The issue argues that innovations in methodology and thoughtful approaches to knowledge translation can enable transparency, quality, and sustainability of intervention research.
Scale-free network provides an optimal pattern for knowledge transfer
NASA Astrophysics Data System (ADS)
Lin, Min; Li, Nan
2010-02-01
We study numerically the knowledge innovation and diffusion process on four representative network models, such as regular networks, small-world networks, random networks and scale-free networks. The average knowledge stock level as a function of time is measured and the corresponding growth diffusion time, τ is defined and computed. On the four types of networks, the growth diffusion times all depend linearly on the network size N as τ∼N, while the slope for scale-free network is minimal indicating the fastest growth and diffusion of knowledge. The calculated variance and spatial distribution of knowledge stock illustrate that optimal knowledge transfer performance is obtained on scale-free networks. We also investigate the transient pattern of knowledge diffusion on the four networks, and a qualitative explanation of this finding is proposed.
Hussain, Rahat; Pedro, Akeem; Lee, Do Yeop; Pham, Hai Chien; Park, Chan Sik
2018-05-01
Despite substantial efforts to improve construction safety training, the accident rate of migrant workers is still high. One of the primary factors contributing to the inefficacy of training includes information delivery gaps during training sessions (knowledge-transfer). In addition, there is insufficient evidence that these training programs alone are effective enough to enable migrant workers to transfer their skills to jobsite (training-transfer). This research attempts to identify and evaluate additional interventions to improve the transfer of acquired knowledge to workplace. For this purpose, this study presents the first known experimental effort to assess the effect of interventions on migrant work groups in a multinational construction project in Qatar. Data analysis reveals that the adoption of training programs with the inclusion of interventions significantly improves training-transfer. Construction safety experts can leverage the findings of this study to enhance training-transfer by increasing worker's safety performance and hazard identification ability.
Wang, Jun; Huang, Jing; Du, Likai; Lan, Zhenggang
2015-07-09
The photoinduced intramolecular excited-state energy-transfer (EET) process in conjugated polymers has received a great deal of research interest because of its important role in the light harvesting and energy transport of organic photovoltaic materials in photoelectric devices. In this work, the silylene-bridged biphenyl and stilbene (SBS) system was chosen as a simplified model system to obtain physical insight into the photoinduced intramolecular energy transfer between the different building units of the SBS copolymer. In the SBS system, the vinylbiphenyl and vinylstilbene moieties serve as the donor (D) unit and the acceptor (A) unit, respectively. The ultrafast excited-state dynamics of the SBS system was investigated from the point of view of nonadiabatic dynamics with the surface-hopping method at the TDDFT level. The first two excited states (S1 and S2) are characterized by local excitations at the acceptor (vinylstilbene) and donor (vinylbiphenyl) units, respectively. Ultrafast S2-S1 decay is responsible for the intramolecular D-A excitonic energy transfer. The geometric distortion of the D moiety play an essential role in this EET process, whereas the A moiety remains unchanged during the nonadiabatic dynamics simulation. The present work provides a direct dynamical approach to understand the ultrafast intramolecular energy-transfer dynamics in SBS copolymers and other similar organic photovoltaic copolymers.
NASA Astrophysics Data System (ADS)
Topousis, Daria E.; Dennehy, Cornelius J.; Lebsock, Kenneth L.
2012-12-01
Historically, engineers at the National Aeronautics and Space Administration (NASA) had few opportunities or incentives to share their technical expertise across the Agency. Its center- and project-focused culture often meant that knowledge never left organizational and geographic boundaries. The need to develop a knowledge sharing culture became critical as a result of increasingly complex missions, closeout of the Shuttle Program, and a new generation of engineers entering the workforce. To address this need, the Office of the Chief Engineer established communities of practice on the NASA Engineering Network. These communities were strategically aligned with NASA's core competencies in such disciplines as avionics, flight mechanics, life support, propulsion, structures, loads and dynamics, human factors, and guidance, navigation, and control. This paper is a case study of NASA's implementation of a system that would identify and develop communities, from establishing simple websites that compiled discipline-specific resources to fostering a knowledge-sharing environment through collaborative and interactive technologies. It includes qualitative evidence of improved availability and transfer of knowledge. It focuses on capabilities that increased knowledge exchange such as a custom-made Ask An Expert system, community contact lists, publication of key resources, and submission forms that allowed any user to propose content for the sites. It discusses the peer relationships that developed through the communities and the leadership and infrastructure that made them possible.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis U.S. academic librarians and technical information specialists as information intermediaries.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis U.S. aerospace engineering faculty and students.
Strategic Evaluation of University Knowledge and Technology Transfer Effectiveness
ERIC Educational Resources Information Center
Tran, Thien Anh
2013-01-01
Academic knowledge and technology transfer has been growing in importance both in academic research and practice. A critical question in managing this activity is how to evaluate its effectiveness. The literature shows an increasing number of studies done to address this question; however, it also reveals important gaps that need more research.…
ERIC Educational Resources Information Center
Kuyken, Kerstin; Ebrahimi, Mehran; Saives, Anne-Laure
2018-01-01
Purpose: This paper aims to develop a better understanding of intergenerational knowledge transfer (IKT) practices by adopting a context-related and comparative perspective. Design/methodology/approach: A qualitative case study design involving 83 interviews and non-participative observation in German and Quebec organizations has been chosen.…
ERIC Educational Resources Information Center
Keown, Kiera; Van Eerd, Dwayne; Irvin, Emma
2008-01-01
Knowledge transfer and exchange is the process of increasing the awareness and use of research evidence in policy or practice decision making by nonresearch audiences or stakeholders. One way to accomplish this end is through ongoing interaction between researchers and interested nonresearch audiences, which provides an opportunity for the two…
ERIC Educational Resources Information Center
Ngoma, Ngoma Sylvestre
2013-01-01
Virtual teams are increasingly viewed as a powerful determinant of competitive advantage in geographically distributed organizations. This study was designed to provide insights into the interdependencies between virtual collaboration, collaboration technologies, knowledge transfer, and virtual team performance in an effort to understand whether…
ERIC Educational Resources Information Center
Ortiz, Lorelei A.
2013-01-01
To teach effective business communication, instructors must target students’ current weaknesses in writing. One method for doing so is by assigning writing exercises. When used heuristically, writing exercises encourage students to practice self-assessment, self-evaluation, active learning, and knowledge transfer, all while reinforcing the basics…
How Global Is the UK Academic Labour Market?
ERIC Educational Resources Information Center
Smetherham, Claire; Fenton, Steve; Modood, Tariq
2010-01-01
One of the themes of the recent sociology of higher education has been the globalisation of knowledge and the professional transfer of scientists and researchers. In this paper we show how these transfers of people and knowledge are disproportionately characteristic of: (a) some institutions; and (b) some cost centres. We argue that universities…
ERIC Educational Resources Information Center
Nielsen, Christian; Cappelen, Katja
2014-01-01
This article discusses mechanisms, enablers and barriers for knowledge transfer in university-industry collaboration projects involving companies, students and researchers. Data is collected through 35 qualitative interviews with Danish and Norwegian representatives from the above categories. All respondents have been involved in collaborative…
Research Knowledge Transfer through Business-Driven Student Assignment
ERIC Educational Resources Information Center
Sas, Corina
2009-01-01
Purpose: The purpose of this paper is to present a knowledge transfer method that capitalizes on both research and teaching dimensions of academic work. It also aims to propose a framework for evaluating the impact of such a method on the involved stakeholders. Design/methodology/approach: The case study outlines and evaluates the six-stage…
Improving Tacit Knowledge Transfer within SMEs through E-Collaboration
ERIC Educational Resources Information Center
Harris, Robert John
2009-01-01
Purpose: The implementation of e-learning can help SMEs to develop skills to cope with their operational environments, but current literature suggests they are not effectively engaged, partly due to a lack of understanding and mistrust of vendors. This paper considers the potential for a more effective transfer of marketing knowledge to firms…
Knowledge and Skills Transfer between MBA and Workplace
ERIC Educational Resources Information Center
Prince, Melvin; Burns, David; Lu, Xinyi; Winsor, Robert
2015-01-01
Purpose: This paper aims to use goal-setting theory to explain the transfer of knowledge and skills between master of business administration (MBA) and the workplace. Design/methodology/approach: Data were obtained by an online survey of MBA students enrolled in at four US graduate business schools. These were a public and private institution in…
Transfer of movement sequences: bigger is better.
Dean, Noah J; Kovacs, Attila J; Shea, Charles H
2008-02-01
Experiment 1 was conducted to determine if proportional transfer from "small to large" scale movements is as effective as transferring from "large to small." We hypothesize that the learning of larger scale movement will require the participant to learn to manage the generation, storage, and dissipation of forces better than when practicing smaller scale movements. Thus, we predict an advantage for transfer of larger scale movements to smaller scale movements relative to transfer from smaller to larger scale movements. Experiment 2 was conducted to determine if adding a load to a smaller scale movement would enhance later transfer to a larger scale movement sequence. It was hypothesized that the added load would require the participants to consider the dynamics of the movement to a greater extent than without the load. The results replicated earlier findings of effective transfer from large to small movements, but consistent with our hypothesis, transfer was less effective from small to large (Experiment 1). However, when a load was added during acquisition transfer from small to large was enhanced even though the load was removed during the transfer test. These results are consistent with the notion that the transfer asymmetry noted in Experiment 1 was due to factors related to movement dynamics that were enhanced during practice of the larger scale movement sequence, but not during the practice of the smaller scale movement sequence. The findings that the movement structure is unaffected by transfer direction but the movement dynamics are influenced by transfer direction is consistent with hierarchal models of sequence production.
Welcome to the techno highway: development of a health assessment CD-ROM and website.
Bosco, Anna Maria; Ward, Catherine
2005-09-01
Traditionally teaching nursing students psychomotor skills took place in a laboratory setting; however, recent developments in computer technology have revolutionised how educators can transfer knowledge. To meet the need for an efficient and interactive learning experience a software product was required to educate nursing students about health assessment techniques. This paper presents how existing 'old technology' of a video was given new life by embracing new technology, resulting in development of an interactive CD-ROM with supporting WebCT. This innovation reflects a more flexible approach to learning as it is dynamic, portable, self-paced and more convenient for adult learners especially those in remote areas.
Analysis of the human operator subsystems
NASA Technical Reports Server (NTRS)
Jones, Lynette A.; Hunter, Ian W.
1991-01-01
Except in low-bandwidth systems, knowledge of the human operator transfer function is essential for high-performance telerobotic systems. This information has usually been derived from detailed analyses of tracking performance, in which the human operator is considered as a complete system rather than as a summation of a number of subsystems, each of which influences the operator's output. Studies of one of these subsystems, the limb mechanics system, demonstrate that large parameter variations can occur that can have a profound effect on the stability of force-reflecting telerobot systems. An objective of this research was to decompose the performance of the human operator system in order to establish how the dynamics of each of the elements influence the operator's responses.
NASA Astrophysics Data System (ADS)
Salvia, Stefano
2017-06-01
Galileo's early inquiries on motion and free fall in Pisa (1588-1592) can be regarded as a case study of multiple knowledge transfer at the very basic roots of modern mechanics. The treatise De motu, unpublished until 1890, is an original but unsuccessful attempt to go beyond Aristotelian physics by extending Archimedean hydrostatics to the dynamics of natural motion and reappraising the late-medieval impetus theory to account for violent motion and acceleration. I will discuss in particular why Galileo was forced to abandon his project before moving to Padua and how the manuscripts De motu provided him with a "research agenda" for further theoretical and experimental investigation.
Damping of coupled harmonic oscillators
NASA Astrophysics Data System (ADS)
Dolfo, Gilles; Vigué, Jacques
2018-03-01
When two harmonic oscillators are coupled in the presence of damping, their dynamics exhibit two very different regimes depending on the relative magnitude of the coupling and damping terms At resonance, when the coupling has its largest effect, if the coupling dominates the damping, there is a periodic exchange of energy between the two oscillators while, in the opposite case, the energy transfer from one oscillator to the other one is irreversible. We prove that the border between these two regimes goes through an exceptional point and we briefly explain what is an exceptional point. The present paper is written for undergraduate students, with some knowledge in classical mechanics, but it may also be of interest for graduate students.
Sentiment classification technology based on Markov logic networks
NASA Astrophysics Data System (ADS)
He, Hui; Li, Zhigang; Yao, Chongchong; Zhang, Weizhe
2016-07-01
With diverse online media emerging, there is a growing concern of sentiment classification problem. At present, text sentiment classification mainly utilizes supervised machine learning methods, which feature certain domain dependency. On the basis of Markov logic networks (MLNs), this study proposed a cross-domain multi-task text sentiment classification method rooted in transfer learning. Through many-to-one knowledge transfer, labeled text sentiment classification, knowledge was successfully transferred into other domains, and the precision of the sentiment classification analysis in the text tendency domain was improved. The experimental results revealed the following: (1) the model based on a MLN demonstrated higher precision than the single individual learning plan model. (2) Multi-task transfer learning based on Markov logical networks could acquire more knowledge than self-domain learning. The cross-domain text sentiment classification model could significantly improve the precision and efficiency of text sentiment classification.
A Conceptual Framework for Examining Knowledge Management in Higher Education Contexts
ERIC Educational Resources Information Center
Lee, Hae-Young; Roth, Gene L.
2009-01-01
Knowledge management is an on-going process that involves varied activities: diagnosis, design, and implementation of knowledge creation, knowledge transfer, and knowledge sharing. The primary goal of knowledge management, like other management theories or models, is to identify and leverage organizational and individual knowledge for the…
2011-01-01
Background Natural acquisition of novel genes from other organisms by horizontal or lateral gene transfer is well established for microorganisms. There is now growing evidence that horizontal gene transfer also plays important roles in the evolution of eukaryotes. Genome-sequencing and EST projects of plant and animal associated nematodes such as Brugia, Meloidogyne, Bursaphelenchus and Pristionchus indicate horizontal gene transfer as a key adaptation towards parasitism and pathogenicity. However, little is known about the functional activity and evolutionary longevity of genes acquired by horizontal gene transfer and the mechanisms favoring such processes. Results We examine the transfer of cellulase genes to the free-living and beetle-associated nematode Pristionchus pacificus, for which detailed phylogenetic knowledge is available, to address predictions by evolutionary theory for successful gene transfer. We used transcriptomics in seven Pristionchus species and three other related diplogastrid nematodes with a well-defined phylogenetic framework to study the evolution of ancestral cellulase genes acquired by horizontal gene transfer. We performed intra-species, inter-species and inter-genic analysis by comparing the transcriptomes of these ten species and tested for cellulase activity in each species. Species with cellulase genes in their transcriptome always exhibited cellulase activity indicating functional integration into the host's genome and biology. The phylogenetic profile of cellulase genes was congruent with the species phylogeny demonstrating gene longevity. Cellulase genes show notable turnover with elevated birth and death rates. Comparison by sequencing of three selected cellulase genes in 24 natural isolates of Pristionchus pacificus suggests these high evolutionary dynamics to be associated with copy number variations and positive selection. Conclusion We could demonstrate functional integration of acquired cellulase genes into the nematode's biology as predicted by theory. Thus, functional assimilation, remarkable gene turnover and selection might represent key features of horizontal gene transfer events in nematodes. PMID:21232122
Mayer, Werner E; Schuster, Lisa N; Bartelmes, Gabi; Dieterich, Christoph; Sommer, Ralf J
2011-01-13
Natural acquisition of novel genes from other organisms by horizontal or lateral gene transfer is well established for microorganisms. There is now growing evidence that horizontal gene transfer also plays important roles in the evolution of eukaryotes. Genome-sequencing and EST projects of plant and animal associated nematodes such as Brugia, Meloidogyne, Bursaphelenchus and Pristionchus indicate horizontal gene transfer as a key adaptation towards parasitism and pathogenicity. However, little is known about the functional activity and evolutionary longevity of genes acquired by horizontal gene transfer and the mechanisms favoring such processes. We examine the transfer of cellulase genes to the free-living and beetle-associated nematode Pristionchus pacificus, for which detailed phylogenetic knowledge is available, to address predictions by evolutionary theory for successful gene transfer. We used transcriptomics in seven Pristionchus species and three other related diplogastrid nematodes with a well-defined phylogenetic framework to study the evolution of ancestral cellulase genes acquired by horizontal gene transfer. We performed intra-species, inter-species and inter-genic analysis by comparing the transcriptomes of these ten species and tested for cellulase activity in each species. Species with cellulase genes in their transcriptome always exhibited cellulase activity indicating functional integration into the host's genome and biology. The phylogenetic profile of cellulase genes was congruent with the species phylogeny demonstrating gene longevity. Cellulase genes show notable turnover with elevated birth and death rates. Comparison by sequencing of three selected cellulase genes in 24 natural isolates of Pristionchus pacificus suggests these high evolutionary dynamics to be associated with copy number variations and positive selection. We could demonstrate functional integration of acquired cellulase genes into the nematode's biology as predicted by theory. Thus, functional assimilation, remarkable gene turnover and selection might represent key features of horizontal gene transfer events in nematodes.
Ultrafast electronic dynamics driven by nuclear motion
NASA Astrophysics Data System (ADS)
Vendrell, Oriol
2016-05-01
The transfer of electrical charge on a microscopic scale plays a fundamental role in chemistry, in biology, and in technological applications. In this contribution, we will discuss situations in which nuclear motion plays a central role in driving the electronic dynamics of photo-excited or photo-ionized molecular systems. In particular, we will explore theoretically the ultrafast transfer of a double electron hole between the functional groups of glycine after K-shell ionization and subsequent Auger decay. Although a large energy gap of about 15 eV initially exists between the two electronic states involved and coherent electronic dynamics play no role in the hole transfer, we will illustrate how the double hole can be transferred within 3 to 4 fs between both functional ends of the glycine molecule driven solely by specific nuclear displacements and non-Born-Oppenheimer effects. This finding challenges the common wisdom that nuclear dynamics of the molecular skeleton are unimportant for charge transfer processes at the few-femtosecond time scale and shows that they can even play a prominent role. We thank the Hamburg Centre for Ultrafast Imaging and the Volkswagen Foundation for financial support.
Protein electron transfer: Dynamics and statistics
NASA Astrophysics Data System (ADS)
Matyushov, Dmitry V.
2013-07-01
Electron transfer between redox proteins participating in energy chains of biology is required to proceed with high energetic efficiency, minimizing losses of redox energy to heat. Within the standard models of electron transfer, this requirement, combined with the need for unidirectional (preferably activationless) transitions, is translated into the need to minimize the reorganization energy of electron transfer. This design program is, however, unrealistic for proteins whose active sites are typically positioned close to the polar and flexible protein-water interface to allow inter-protein electron tunneling. The high flexibility of the interfacial region makes both the hydration water and the surface protein layer act as highly polar solvents. The reorganization energy, as measured by fluctuations, is not minimized, but rather maximized in this region. Natural systems in fact utilize the broad breadth of interfacial electrostatic fluctuations, but in the ways not anticipated by the standard models based on equilibrium thermodynamics. The combination of the broad spectrum of static fluctuations with their dispersive dynamics offers the mechanism of dynamical freezing (ergodicity breaking) of subsets of nuclear modes on the time of reaction/residence of the electron at a redox cofactor. The separation of time-scales of nuclear modes coupled to electron transfer allows dynamical freezing. In particular, the separation between the relaxation time of electro-elastic fluctuations of the interface and the time of conformational transitions of the protein caused by changing redox state results in dynamical freezing of the latter for sufficiently fast electron transfer. The observable consequence of this dynamical freezing is significantly different reorganization energies describing the curvature at the bottom of electron-transfer free energy surfaces (large) and the distance between their minima (Stokes shift, small). The ratio of the two reorganization energies establishes the parameter by which the energetic efficiency of protein electron transfer is increased relative to the standard expectations, thus minimizing losses of energy to heat. Energetically efficient electron transfer occurs in a chain of conformationally quenched cofactors and is characterized by flattened free energy surfaces, reminiscent of the flat and rugged landscape at the stability basin of a folded protein.
Protein electron transfer: Dynamics and statistics.
Matyushov, Dmitry V
2013-07-14
Electron transfer between redox proteins participating in energy chains of biology is required to proceed with high energetic efficiency, minimizing losses of redox energy to heat. Within the standard models of electron transfer, this requirement, combined with the need for unidirectional (preferably activationless) transitions, is translated into the need to minimize the reorganization energy of electron transfer. This design program is, however, unrealistic for proteins whose active sites are typically positioned close to the polar and flexible protein-water interface to allow inter-protein electron tunneling. The high flexibility of the interfacial region makes both the hydration water and the surface protein layer act as highly polar solvents. The reorganization energy, as measured by fluctuations, is not minimized, but rather maximized in this region. Natural systems in fact utilize the broad breadth of interfacial electrostatic fluctuations, but in the ways not anticipated by the standard models based on equilibrium thermodynamics. The combination of the broad spectrum of static fluctuations with their dispersive dynamics offers the mechanism of dynamical freezing (ergodicity breaking) of subsets of nuclear modes on the time of reaction/residence of the electron at a redox cofactor. The separation of time-scales of nuclear modes coupled to electron transfer allows dynamical freezing. In particular, the separation between the relaxation time of electro-elastic fluctuations of the interface and the time of conformational transitions of the protein caused by changing redox state results in dynamical freezing of the latter for sufficiently fast electron transfer. The observable consequence of this dynamical freezing is significantly different reorganization energies describing the curvature at the bottom of electron-transfer free energy surfaces (large) and the distance between their minima (Stokes shift, small). The ratio of the two reorganization energies establishes the parameter by which the energetic efficiency of protein electron transfer is increased relative to the standard expectations, thus minimizing losses of energy to heat. Energetically efficient electron transfer occurs in a chain of conformationally quenched cofactors and is characterized by flattened free energy surfaces, reminiscent of the flat and rugged landscape at the stability basin of a folded protein.
Lv, Kai; Qin, Long; Wang, Xiufeng; Zhang, Li; Liu, Minghua
2013-12-14
Chirality transfer is an interesting phenomenon in Nature, which represents an important step to understand the evolution of chiral bias and the amplification of the chirality. In this paper, we report the chirality transfer via the entanglement of the alkyl chains between chiral gelator molecules and achiral amphiphilic Schiff base. We have found that although an achiral Schiff base amphiphile could not form organogels in any kind of organic solvents, it formed co-organogels when mixed with a chiral gelator molecule. Interestingly, the chirality of the gelator molecules was transferred to the Schiff base chromophore in the mixed co-gels and there was a maximum mixing ratio for the chirality transfer. Furthermore, the supramolecular chirality was also produced based on a dynamic covalent chemistry of an imine formed by the reaction between an aldehyde and an amine. Such a covalent bond of imine was formed reversibly depending on the pH variation. When the covalent bond was formed the chirality transfer occurred, when it was destroyed, the transfer stopped. Thus, a supramolecular chiroptical switch is obtained based on supramolecular chirality transfer and dynamic covalent chemistry.
Knowledge Co-production Strategies for Water Resources Modeling and Decision Making
NASA Astrophysics Data System (ADS)
Gober, P.
2016-12-01
The limited impact of scientific information on policy making and climate adaptation in North America has raised awareness of the need for new modeling strategies and knowledge transfer processes. This paper outlines the rationale for a new paradigm in water resources modeling and management, using examples from the USA and Canada. Principles include anticipatory modeling, complex system dynamics, decision making under uncertainty, visualization, capacity to represent and manipulate critical trade-offs, stakeholder engagement, local knowledge, context-specific activities, social learning, vulnerability analysis, iterative and collaborative modeling, and the concept of a boundary organization. In this framework, scientists and stakeholders are partners in the production and dissemination of knowledge for decision making, and local knowledge is fused with scientific observation and methodology. Discussion draws from experience in building long-term collaborative boundary organizations in Phoenix, Arizona in the USA and the Saskatchewan River Basin (SRB) in Canada. Examples of boundary spanning activities include the use of visualization, the concept of a decision theater, infrastructure to support social learning, social networks, and reciprocity, simulation modeling to explore "what if" scenarios of the future, surveys to elicit how water problems are framed by scientists and stakeholders, and humanistic activities (theatrical performances, art exhibitions, etc.) to draw attention to local water issues. The social processes surrounding model development and dissemination are at least as important as modeling assumptions, procedures, and results in determining whether scientific knowledge will be used effectively for water resources decision making.
Nonadiabatic Dynamics of Photoinduced Proton-Coupled Electron Transfer Processes
devices and photoelectrochemical cells. Theoretical methodology for simulating the nonadiabatic dynamics of photoinduced PCET reactions in solution has...tuning and control of the ultrafast dynamics is crucial for designing renewable and sustainable energy sources, such as artificial photosynthesis...describes the solute with a multiconfigurational method in a bath of explicit solvent molecules. The transferring hydrogen nucleus is represented as a
Dynamic Modulation of Radiative Heat Transfer beyond the Blackbody Limit.
Ito, Kota; Nishikawa, Kazutaka; Miura, Atsushi; Toshiyoshi, Hiroshi; Iizuka, Hideo
2017-07-12
Dynamic control of electromagnetic heat transfer without changing mechanical configuration opens possibilities in intelligent thermal management in nanoscale systems. We confirmed by experiment that the radiative heat transfer is dynamically modulated beyond the blackbody limit. The near-field electromagnetic heat exchange mediated by phonon-polariton is controlled by the metal-insulator transition of tungsten-doped vanadium dioxide. The functionalized heat flux is transferred over an area of 1.6 cm 2 across a 370 nm gap, which is maintained by the microfabricated spacers and applied pressure. The uniformity of the gap is validated by optical interferometry, and the measured heat transfer is well modeled as the sum of the radiative and the parasitic conductive components. The presented methodology to form a nanometric gap with functional heat flux paves the way to the smart thermal management in various scenes ranging from highly integrated systems to macroscopic apparatus.
Invisible Transfer: An Unexpected Finding in the Pursuit of Transfer
ERIC Educational Resources Information Center
Schieber, Danica L.
2016-01-01
Much research shows that students do not transfer learning well from one class to the next. This study was designed to investigate if students were transferring rhetorical strategies from their disciplinary courses to advanced writing courses. The findings suggest that business majors not only transferred rhetorical knowledge from their other…
ERIC Educational Resources Information Center
Alawneh, Muhammad K.
2008-01-01
This article investigates factors that motivate participants in learning and training activities to transfer skills, knowledge and attitude from the learning setting to the workplace. Based on training transfer theories hypothesized by Holton (1996), one of the major theories that affect an organization's learning is motivation to transfer theory.…
Probing conformational dynamics by photoinduced electron transfer
NASA Astrophysics Data System (ADS)
Neuweiler, Hannes; Herten, Dirk P.; Marme, N.; Knemeyer, J. P.; Piestert, Oliver; Tinnefeld, Philip; Sauer, Marcus
2004-07-01
We demonstrate how photoinduced electron transfer (PET) reactions can be successfully applied to monitor conformational dynamics in individual biopolymers. Single-pair fluorescence resonance energy transfer (FRET) experiments are ideally suited to study conformational dynamics occurring on the nanometer scale, e.g. during protein folding or unfolding. In contrast, conformational dynamics with functional significance, for example occurring in enzymes at work, often appear on much smaller spatial scales of up to several Angströms. Our results demonstrate that selective PET-reactions between fluorophores and amino acids or DNA nucleotides represent a versatile tool to measure small-scale conformational dynamics in biopolymers on a wide range of time scales, extending from nanoseconds to seconds, at the single-molecule level under equilibrium conditions. That is, the monitoring of conformational dynamics of biopolymers with temporal resolutions comparable to those within reach using new techniques of molecular dynamic simulations. We present data about structural changes of single biomolecules like DNA hairpins and peptides by using quenching electron transfer reactions between guanosine or tryptophan residues in close proximity to fluorescent dyes. Furthermore, we demonstrate that the strong distance dependence of charge separation reactions on the sub-nanometer scale can be used to develop conformationally flexible PET-biosensors. These sensors enable the detection of specific target molecules in the sub-picomolar range and allow one to follow their molecular binding dynamics with temporal resolution.
Cori, Liliana; Carducci, Annalaura; Donzelli, Gabriele; La Rocca, Cinzia; Bianchi, Fabrizio
2018-01-01
Eleven projects within the LIFE programme (through which the Directorate-General for Environment of the European Commission provides funding for projects aim at protecting environment and nature) addressing environmental-health-related issues have been involved in a collaborative network called KTE LIFE EnvHealth Network. The shared issues tackled by that projects are knowledge transfer and exchange (KTE). The objective of the LIFE programme is to support the implementation of the environmental legislation in the European Union, to provide new tools and knowledge that will help to better protect both the territory and the communities. Transferring knowledge to decision makers, at the appropriate and effective level, is therefore a central function of the projects. The Network promotes national and international networking, which intends to involve other projects, to provide methodological support, to make information and successful practices circulate, with the aim of multiplying the energies of each project involved.
Prihodova, Lucia; Guerin, Suzanne; Kernohan, W George
2015-07-01
To review knowledge transfer and exchange frameworks used in health, to analyse the core concepts of these frameworks and appraise their potential applicability to palliative care. Although there are over 60 different models of knowledge transfer and exchange designed for various areas of the fields of health care, many remain largely unrefined and untested. There is a lack of studies that create guidelines for scaling-up successful implementation of research findings and of proven models ensuring that patients have access to optimal health care, guided by current research. The protocol for this scoping review was devised according to the guidelines proposed by Arksey and O'Malley (2005) and Levac et al. (2010). The protocol includes decisions about the review objectives, inclusion criteria, search strategy, study selection, data extraction, quality assessment, data synthesis and plans for dissemination. The review will allow us to identify the currently used models of knowledge transfer and exchange in healthcare setting and analyse their applicability to the complex demands of palliative care. Results from this review will identify effective way of translating different types of knowledge to different PC providers and could be used in hospital, community and home based PC and future research. © 2015 John Wiley & Sons Ltd.
Evaluating Technology Transfer and Diffusion.
ERIC Educational Resources Information Center
Bozeman, Barry; And Others
1988-01-01
Four articles discuss the evaluation of technology transfer and diffusion: (1) "Technology Transfer at the U.S. National Laboratories: A Framework for Evaluation"; (2) "Application of Social Psychological and Evaluation Research: Lessons from Energy Information Programs"; (3) "Technology and Knowledge Transfer in Energy R and D Laboratories: An…
NASA Astrophysics Data System (ADS)
Yuan, Shifei; Jiang, Lei; Yin, Chengliang; Wu, Hongjie; Zhang, Xi
2017-06-01
The electrochemistry-based battery model can provide physics-meaningful knowledge about the lithium-ion battery system with extensive computation burdens. To motivate the development of reduced order battery model, three major contributions have been made throughout this paper: (1) the transfer function type of simplified electrochemical model is proposed to address the current-voltage relationship with Padé approximation method and modified boundary conditions for electrolyte diffusion equations. The model performance has been verified under pulse charge/discharge and dynamic stress test (DST) profiles with the standard derivation less than 0.021 V and the runtime 50 times faster. (2) the parametric relationship between the equivalent circuit model and simplified electrochemical model has been established, which will enhance the comprehension level of two models with more in-depth physical significance and provide new methods for electrochemical model parameter estimation. (3) four simplified electrochemical model parameters: equivalent resistance Req, effective diffusion coefficient in electrolyte phase Deeff, electrolyte phase volume fraction ε and open circuit voltage (OCV), have been identified by the recursive least square (RLS) algorithm with the modified DST profiles under 45, 25 and 0 °C. The simulation results indicate that the proposed model coupled with RLS algorithm can achieve high accuracy for electrochemical parameter identification in dynamic scenarios.
NASA Astrophysics Data System (ADS)
Campbell, Timothy; Kalia, Rajiv K.; Nakano, Aiichiro; Vashishta, Priya; Ogata, Shuji; Rodgers, Stephen
1999-06-01
Oxidation of aluminum nanoclusters is investigated with a parallel molecular-dynamics approach based on dynamic charge transfer among atoms. Structural and dynamic correlations reveal that significant charge transfer gives rise to large negative pressure in the oxide which dominates the positive pressure due to steric forces. As a result, aluminum moves outward and oxygen moves towards the interior of the cluster with the aluminum diffusivity 60% higher than that of oxygen. A stable 40 Å thick amorphous oxide is formed; this is in excellent agreement with experiments.
Single-molecule interfacial electron transfer dynamics in solar energy conversion
NASA Astrophysics Data System (ADS)
Dhital, Bharat
This dissertation work investigated the parameters affecting the interfacial electron transfer (ET) dynamics in dye-semiconductor nanoparticles (NPs) system by using single-molecule fluorescence spectroscopy and imaging combined with electrochemistry. The influence of the molecule-substrate electronic coupling, the molecular structure, binding geometry on the surface and the molecule-attachment surface chemistry on interfacial charge transfer processes was studied on zinc porphyrin-TiO2 NP systems. The fluorescence blinking measurement on TiO2 NP demonstrated that electronic coupling regulates dynamics of charge transfer processes at the interface depending on the conformation of molecule on the surface. Moreover, semiconductor surface charge induced electronic coupling of molecule which is electrostatically adsorbed on the semiconductor surface also predominantly alters the ET dynamics. Furthermore, interfacial electric field and electron accepting state density dependent ET dynamics has been dissected in zinc porphyrin-TiO2 NP system by observing the single-molecule fluorescence blinking dynamics and fluorescence lifetime with and without applied bias. The significant difference in fluorescence fluctuation and lifetime suggested the modulation of charge transfer dynamics at the interface with external electric field perturbation. Quasi-continuous distribution of fluorescence intensity with applied negative potential was attributed to the faster charge recombination due to reduced density of electron accepting states. The driving force and electron accepting state density ET dependent dynamics has also been probed in zinc porphyrin-TiO2 NP and zinc porphyrin-indium tin oxide (ITO) systems. Study of a molecule adsorbed on two different semiconductors (ITO and TiO2), with large difference in electron densities and distinct driving forces, allows us to observe the changes in rates of back electron transfer process reflected by the suppressed fluorescence blinking of molecule on ITO surface. Finally, the electric field effect on the interface properties has been probed by using surface-enhanced Raman spectroscopy and supported by density functional theory calculations in alizarin-TiO2 system. The perturbation, created by the external potential, has been observed to cause a shift and/or splitting interfacial bond vibrational mode, typical indicator of the coupling energy changes between alizarin and TiO2. Such splitting provides evidence for electric field-dependent electronic coupling changes that have a significant impact on the interfacial electron transfer dynamics.
NASA Astrophysics Data System (ADS)
Plotnikov, L. V.
2017-09-01
Comparison of experimental research results of gas dynamics and instantaneous local heat transfer in the intake pipes for piston internal combustion engines (ICE) without and with supercharging are presented in the article. Studies were conducted on full-scale experimental setups in terms of gas dynamic nonstationarity, which is characteristic of piston engines. It has been established that the turbocharger installation in a gas-air system of piston internal combustion engine leads to significant differences in the patterns of change in gas-dynamic and heat transfer characteristics of flows. These data can be used in a modernization of piston engines due to installation of a turbocharger or in a development of gas-air systems for piston ICE with supercharging.
Amlo, S; Engelstad, V; Fossum, A; Sørlie, T; Høglend, P; Heyerdahl, O; Sørbye, O
1993-01-01
The authors examined whether persistent analysis of the patient-therapist relationship in brief dynamic psychotherapy favorably affects long-term dynamic change in patients initially deemed suitable for such treatment. As in common practice, 22 highly suitable patients were given a high number of transference interpretations per session. A comparison group of 21 patients with lower suitability received the same treatment, but transference interpretations were withheld. Statistical adjustment for the deliberate nonequivalence in pretreatment suitability indicated a significant negative effect of high numbers of transference interpretations on long-term dynamic changes. Demographic variables, DSM-III diagnoses, additional treatment, life events in the follow-up years, or therapist effects did not explain or obscure the findings.
Bharadwaj, Vivek S; Dean, Anthony M; Maupin, C Mark
2013-08-21
The fumarate addition reaction, catalyzed by the enzyme benzylsuccinate synthase (BSS), is considered to be one of the most intriguing and energetically challenging reactions in biology. BSS belongs to the glycyl radical enzyme family and catalyzes the fumarate addition reaction, which enables microorganisms to utilize hydrocarbons as an energy source under anaerobic conditions. Unfortunately, the extreme sensitivity of the glycyl radical to oxygen has hampered the structural and kinetic characterization of BSS, thereby limiting our knowledge on this enzyme. To enhance our molecular-level understanding of BSS, a computational approach involving homology modeling, docking studies, and molecular dynamics (MD) simulations has been used to deduce the structure of BSS's catalytic subunit (BSSα) and illuminate the molecular basis for the fumarate addition reaction. We have identified two conserved and distinct binding pockets at the BSSα active site: a hydrophobic pocket for toluene binding and a polar pocket for fumaric acid binding. Subsequent dynamical and energetic evaluations have identified Glu509, Ser827, Leu390, and Phe384 as active site residues critical for substrate binding. The orientation of substrates at the active site observed in MD simulations is consistent with experimental observations of the syn addition of toluene to fumaric acid. It is also found that substrate binding tightens the active site and restricts the conformational flexibility of the thiyl radical, leading to hydrogen transfer distances conducive to the proposed reaction mechanism. The stability of substrates at the active site and the occurrence of feasible radical transfer distances between the thiyl radical, substrates, and the active site glycine indicate a substrate-assisted radical transfer pathway governing fumarate addition.
NASA Astrophysics Data System (ADS)
Loye, Alexandre; Jaboyedoff, Michel; Theule, Joshua Isaac; Liébault, Frédéric
2016-06-01
Debris flows have been recognized to be linked to the amounts of material temporarily stored in torrent channels. Hence, sediment supply and storage changes from low-order channels of the Manival catchment, a small tributary valley with an active torrent system located exclusively in sedimentary rocks of the Chartreuse Massif (French Alps), were surveyed periodically for 16 months using terrestrial laser scanning (TLS) to study the coupling between sediment dynamics and torrent responses in terms of debris flow events, which occurred twice during the monitoring period. Sediment transfer in the main torrent was monitored with cross-section surveys. Sediment budgets were generated seasonally using sequential TLS data differencing and morphological extrapolations. Debris production depends strongly on rockfall occurring during the winter-early spring season, following a power law distribution for volumes of rockfall events above 0.1 m3, while hillslope sediment reworking dominates debris recharge in spring and autumn, which shows effective hillslope-channel coupling. The occurrence of both debris flow events that occurred during the monitoring was linked to recharge from previous debris pulses coming from the hillside and from bedload transfer. Headwater debris sources display an ambiguous behaviour in sediment transfer: low geomorphic activity occurred in the production zone, despite rainstorms inducing debris flows in the torrent; still, a general reactivation of sediment transport in headwater channels was observed in autumn without new debris supply, suggesting that the stored debris was not exhausted. The seasonal cycle of sediment yield seems to depend not only on debris supply and runoff (flow capacity) but also on geomorphic conditions that destabilize remnant debris stocks. This study shows that monitoring the changes within a torrent's in-channel storage and its debris supply can improve knowledge on recharge thresholds leading to debris flow.
A Proposed Model for Authenticating Knowledge Transfer in Online Discussion Forums
ERIC Educational Resources Information Center
Tucker, Jan P.; YoungGonzaga, Stephanie; Krause, Jaclyn
2014-01-01
Discussion forums are often utilized in the online classroom to build a sense of community, encourage collaboration and exchange, and measure time on task. A review of the literature revealed that there is little research that examines the role of the online discussion forum as a mechanism for knowledge transfer. Researchers reviewed 21 course…
ERIC Educational Resources Information Center
Phelan, Jack Gordon
2012-01-01
This study examined the effects of a critical thinking instructional intervention in a higher education technology course with the purpose of determining the extent to which the intervention enhanced student critical thinking knowledge, skills, dispositions, application and transfer abilities. Historically, critical thinking has been considered…
ERIC Educational Resources Information Center
Belenky, Daniel M.; Nokes-Malach, Timothy J.
2013-01-01
Although prior work has shown that mastery-approach achievement goals are related to positive learning behaviors (e.g., more interest, perseverance, and self-regulation), less is known about how these goals interact with instruction to influence knowledge transfer. To address these issues we conducted a laboratory experiment investigating how two…
A Conceptual Change Model for Teaching Heat Energy, Heat Transfer and Insulation
ERIC Educational Resources Information Center
Lee, C. K.
2014-01-01
This study examines the existing knowledge that pre-service elementary teachers (PSETs) have regarding heat energy, heat transfer and insulation. The PSETs' knowledge of heat energy was initially assessed by using an activity: determining which container would be best to keep hot water warm for the longest period of time. Results showed that PSETs…
Knowledge Transfer: What, How, and Why
ERIC Educational Resources Information Center
Chin, Si-Chi
2013-01-01
People learn from prior experiences. We first learn how to use a spoon and then know how to use a different size of spoon. We first learn how to sew and then learn how to embroider. Transferring knowledge from one situation to another related situation often increases the speed of learning. This observation is relevant to human learning, as well…
Slope and Line of Best Fit: A Transfer of Knowledge Case Study
ERIC Educational Resources Information Center
Nagle, Courtney; Casey, Stephanie; Moore-Russo, Deborah
2017-01-01
This paper brings together research on slope from mathematics education and research on line of best fit from statistics education by considering what knowledge of slope students transfer to a novel task involving determining the placement of an informal line of best fit. This study focuses on two students who transitioned from placing inaccurate…
Running Risks of Gender Inequity: Knowledge Transfer Policy in Australian Higher Education
ERIC Educational Resources Information Center
Gaze, Beth; Stevens, Carolyn
2011-01-01
Knowledge transfer (KT), or third stream activities of universities, has attracted attention from funding and regulatory bodies in recent years. While approaches differ from country to country, moves to improve measurement and monitoring of such activities with a view to encourage or better direct it have occurred in several settings. This article…
ERIC Educational Resources Information Center
Scheder, Catherine M.
2016-01-01
This qualitative study explored lived experiences of eight youth-camp alumni who were enrolled in colleges. This study was grounded in four paradigms: knowledge application, positive youth development (PYD), personal skills, and social integration. The key findings of this study were transfer of learning between skills learned in youth programs…
ERIC Educational Resources Information Center
Ellington, Virginia Beth Elder
2012-01-01
This research study was undertaken to gain a richer understanding of the use of patient-introduced online health information during the physician/patient examination and knowledge transfer process. Utilizing qualitative data obtained from ten family physician interviews and workflow modeling using activity diagrams and task structure charts, this…
ERIC Educational Resources Information Center
Amara, Nabil; Landry, Rejean; Halilem, Norrin
2013-01-01
Academic consulting is a form of knowledge and technology transfer largely under-documented and under-studied that raises ethical and resources allocation issues. Based on a survey of 2,590 Canadian researchers in engineering and natural sciences, this paper explores three forms of academic consulting: (1) paid consulting; (2) unpaid consulting…
ERIC Educational Resources Information Center
Olivares, Rafael A.; Lemberger, Nancy
2002-01-01
Provides recommendations for the implementation of the communication, constructivism, and transference of knowledge (CCT) model in the education of English language learners (ELLS). Describes how the CCT model is identified in research studies and suggests specific recommendations to facilitate the implementation of the model in the education of…
ERIC Educational Resources Information Center
Raza, Syed Ali; Najmi, Arsalan; Shah, Nida
2018-01-01
Purpose: This paper aims to explore the significance of knowledge transfer (KT) from universities to organizations by employing in-service employees, who are working in organizations and at the same time studying in the universities, as the channel. Design/methodology/approach: By using survey methodology, data were collected from 216 in-service…
Encouraging Cognitive Connections and Creativity in the Music Classroom
ERIC Educational Resources Information Center
Peterson, Christopher W.; Madsen, Clifford K.
2010-01-01
The ability to apply knowledge rests at the core of the educational experience and is an important aspect of all teaching. In music education, many experiences are structured so information gained can be related to another activity, but such transfer can be difficult. When students learn to transfer information and knowledge to new situations,…
Delton Alderman; Kent Nakamoto; David Briberg
2007-01-01
Technology and knowledge transfer (TKT) is practiced for a plethora of causes, ranging from AIDS prevention to manufacturing competitiveness. The number of government, university, and association TKT efforts is exhausting and fraught with problems; we know anecdotally that the adoption of technology or knowledge is minimal across all contexts. There are a myriad of...
Wang, Fang; Zhang, Yonglai; Liu, Yang; Wang, Xuefeng; Shen, Mingrong; Lee, Shuit-Tong; Kang, Zhenhui
2013-03-07
Here we show a bias-mediated electron/energy transfer process at the CQDs-TiO(2) interface for the dynamic modulation of opto-electronic properties. Different energy and electron transfer states have been observed in the CQDs-TNTs system due to the up-conversion photoluminescence and the electron donation/acceptance properties of the CQDs decorated on TNTs.
NASA Astrophysics Data System (ADS)
Nagothu, U. S.
2016-12-01
Agricultural extension services, among others, contribute to improving rural livelihoods and enhancing economic development. Knowledge development and transfer from the cognitive science point of view, is about, how farmers use and apply their experiential knowledge as well as acquired new knowledge to solve new problems. This depends on the models adopted, the way knowledge is generated and delivered. New extension models based on ICT platforms and smart phones are promising. Results from a 5-year project (www.climaadapt.org) in India shows that farmer led-on farm validations of technologies and knowledge exchange through ICT based platforms outperformed state operated linear extension programs. Innovation here depends on the connectivity, net-working between stakeholders that are involved in generating, transferring and using the knowledge. Key words: Smallholders, Knowledge, Extension, Innovation, India
Passive vs Active Knowledge Transfer: boosting grant proposal impact
NASA Astrophysics Data System (ADS)
Grigorov, Ivo; Bayliss-Brown, Georgia; Murphy, David; Thøgersen, Thomas; Mariani, Patrizio
2017-04-01
Research funders are increasingly concerned with measurable socio-economic impact of investment in research, and on increasingly shorter timescales. Innovation, and "open innovation" are the policy priorities of the moment and optimising the flow of ideas along the lab-2-market spectrum is essential for re-use of results, fuelling open innovation, and boosting socio-economic impact or public funded research. The presentation showcases two complimentary strategies that Project Managers can employ pre- and/or post-award in order to optimise the exploitation and impact of research project: passive and active knowledge transfer. Passive Knowledge Transfer relies on maximum disclosure of research output (other than commercially exploitable research via patents and other IPR) in the interest of optimal reproducibility, independent validation and re-use by both academic and non-academic users, without necessarily targeting specific users. Tools of the trade include standard public & academic dissemination means (research articles, online media publications, newsletters, generic policy briefs). Additional transparency of the research workflow can be achieved by integrating "open science" (open notebooks, open data, open research software and open access to research publications) as well as Virtual Research Environments (VREs) in the methodology of the proposed work. Ensuring that the proposal partners are suitably trained in best practices of open science, makes proposal grant more competitive at evaluation and the resulting maximum access to research outputs does contribute to better return on investment for funders (Beagrie 2016) and economic growth objectives of public s e.g. Blue Growth (Houghton & Swan 2011, Marine Knowledge 2020 Roadmap). Active Knowledge Transfer, or the pro-active translation of research into policy or commercial context, is the more classical and better known approach (also referred to as extension services, or researchers providing advice e.g. to fisheries and aquaculture governance bodies and private sector). Horizon2020 COLUMBUS Consortium proposes and tests a methodology for categorizing the diverse output of research into verifiable "knowledge outputs" , and documenting the execution of an transfer plan to very specific and identified potential users, in order to transfer knowledge along the lab-2-market spectrum. The presentation will demonstrate how Open Science and detailed knowledge transfer plans complement each other, enhance grant proposal evaluation pre- and post-award, and can address Blue Growth policy objectives. Concepts presented are developed by FP7/H2020 FOSTER (www.fosteropenscience.eu), H2020 COLUMBUS (www.columbusproject.eu) References: Beagrie, Neil, and Charles Beagrie. "The Value and Impact of the European Bioinformatics Institute," January 2016. http://www.beagrie.com/static/resource/EBI-impact-report.pdf Houghton, John, Alma Swan, and Sheridan Brown. "Access to Research and Technical Information in Denmark." Monograph, April 2011. http://eprints.soton.ac.uk/272603/ Marine Knowledge 2020: roadmap http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=SWD:2014:149:FIN
NASA Astrophysics Data System (ADS)
Rettberg, P.; Ellis-Evans, C.; Prieur, D.; Loreto, F.; Walter, N.; Le Bris, N.; Elster, J.; Amils, R.; Marteinsson, V.
2008-09-01
Life in Extreme Environments is an emerging area of research in which Europe has considerable expertise but a relatively fragmented research infrastructure. The science of such environments has enormous relevance for our knowledge of the diversity and environmental limits of microbial, plant and animal life and the novel strategies employed for survival and growth. Such studies are essential in understanding how life established on the early Earth and in assessing the possibilities for life on other planetary bodies. These environments are also a rich source of novel exploitable compounds. At the European level, there is a need for better coordination of life in extreme environments research, the FP7-funded CAREX project aims to address this need by developing a clearly identifiable, dynamic and durable community. Establishing this community will encourage greater interdisciplinarity and increasing knowledge of extreme environments. It will provide a target for young career scientists and allow a more focussed dialogue with other science areas, with funding agencies, with industrial groups and with international organisations outside Europe. CAREX will last for three years and with a wide scope covering microbial life, plant adaptation and animal adaptation to various marine, polar, terrestrial extreme environments as well as outer space. CAREX's outputs will include a strategic roadmap for European life in extreme environments research (including enabling technologies), diverse opportunities for knowledge transfer, standardisation of methodologies, encouragement and support for early career scientists and a network of links to relevant organisations. These deliverables together with improved community networking, supported by newsletters, promotional leaflets, a series of science publications and an interactive web portal, will help consolidate the community and its identity. Outcomes will be facilitated through science/technology workshops, diverse forums, field/laboratory protocol intercomparisons, a summer school and individual grants to facilitate knowledge transfer. CAREX has evolved with the key players from the highly successful ESF "Investigating Life in Extreme Environments" initiative. For more information: www.carex-eu.org
Proton transfer reactions and dynamics in CH(3)OH-H(3)O(+)-H(2)O complexes.
Sagarik, Kritsana; Chaiwongwattana, Sermsiri; Vchirawongkwin, Viwat; Prueksaaroon, Supakit
2010-01-28
Proton transfer reactions and dynamics in hydrated complexes formed from CH(3)OH, H(3)O(+) and H(2)O were studied using theoretical methods. The investigations began with searching for equilibrium structures at low hydration levels using the DFT method, from which active H-bonds in the gas phase and continuum aqueous solution were characterized and analyzed. Based on the asymmetric stretching coordinates (Deltad(DA)), four H-bond complexes were identified as potential transition states, in which the most active unit is represented by an excess proton nearly equally shared between CH(3)OH and H(2)O. These cannot be definitive due to the lack of asymmetric O-H stretching frequencies (nu(OH)) which are spectral signatures of transferring protons. Born-Oppenheimer molecular dynamics (BOMD) simulations revealed that, when the thermal energy fluctuations and dynamics were included in the model calculations, the spectral signatures at nu(OH) approximately 1000 cm(-1) appeared. In continuum aqueous solution, the H-bond complex with incomplete water coordination at charged species turned out to be the only active transition state. Based on the assumption that the thermal energy fluctuations and dynamics could temporarily break the H-bonds linking the transition state complex and water molecules in the second hydration shell, elementary reactions of proton transfer were proposed. The present study showed that, due to the coupling among various vibrational modes, the discussions on proton transfer reactions cannot be made based solely on static proton transfer potentials. Inclusion of thermal energy fluctuations and dynamics in the model calculations, as in the case of BOMD simulations, together with systematic IR spectral analyses, have been proved to be the most appropriate theoretical approaches.
Serotonergic psychedelics temporarily modify information transfer in humans.
Alonso, Joan Francesc; Romero, Sergio; Mañanas, Miquel Àngel; Riba, Jordi
2015-03-28
Psychedelics induce intense modifications in the sensorium, the sense of "self," and the experience of reality. Despite advances in our understanding of the molecular and cellular level mechanisms of these drugs, knowledge of their actions on global brain dynamics is still incomplete. Recent imaging studies have found changes in functional coupling between frontal and parietal brain structures, suggesting a modification in information flow between brain regions during acute effects. Here we assessed the psychedelic-induced changes in directionality of information flow during the acute effects of a psychedelic in humans. We measured modifications in connectivity of brain oscillations using transfer entropy, a nonlinear measure of directed functional connectivity based on information theory. Ten healthy male volunteers with prior experience with psychedelics participated in 2 experimental sessions. They received a placebo or a dose of ayahuasca, a psychedelic preparation containing the serotonergic 5-HT2A agonist N,N-dimethyltryptamine. The analysis showed significant changes in the coupling of brain oscillations between anterior and posterior recording sites. Transfer entropy analysis showed that frontal sources decreased their influence over central, parietal, and occipital sites. Conversely, sources in posterior locations increased their influence over signals measured at anterior locations. Exploratory correlations found that anterior-to-posterior transfer entropy decreases were correlated with the intensity of subjective effects, while the imbalance between anterior-to-posterior and posterior-to-anterior transfer entropy correlated with the degree of incapacitation experienced. These results suggest that psychedelics induce a temporary disruption of neural hierarchies by reducing top-down control and increasing bottom-up information transfer in the human brain. © The Author 2015. Published by Oxford University Press on behalf of CINP.
Valenza, Gaetano; Faes, Luca; Citi, Luca; Orini, Michele; Barbieri, Riccardo
2018-05-01
Measures of transfer entropy (TE) quantify the direction and strength of coupling between two complex systems. Standard approaches assume stationarity of the observations, and therefore are unable to track time-varying changes in nonlinear information transfer with high temporal resolution. In this study, we aim to define and validate novel instantaneous measures of TE to provide an improved assessment of complex nonstationary cardiorespiratory interactions. We here propose a novel instantaneous point-process TE (ipTE) and validate its assessment as applied to cardiovascular and cardiorespiratory dynamics. In particular, heartbeat and respiratory dynamics are characterized through discrete time series, and modeled with probability density functions predicting the time of the next physiological event as a function of the past history. Likewise, nonstationary interactions between heartbeat and blood pressure dynamics are characterized as well. Furthermore, we propose a new measure of information transfer, the instantaneous point-process information transfer (ipInfTr), which is directly derived from point-process-based definitions of the Kolmogorov-Smirnov distance. Analysis on synthetic data, as well as on experimental data gathered from healthy subjects undergoing postural changes confirms that ipTE, as well as ipInfTr measures are able to dynamically track changes in physiological systems coupling. This novel approach opens new avenues in the study of hidden, transient, nonstationary physiological states involving multivariate autonomic dynamics in cardiovascular health and disease. The proposed method can also be tailored for the study of complex multisystem physiology (e.g., brain-heart or, more in general, brain-body interactions).
Diversity of sharp-wave-ripple LFP signatures reveals differentiated brain-wide dynamical events.
Ramirez-Villegas, Juan F; Logothetis, Nikos K; Besserve, Michel
2015-11-17
Sharp-wave-ripple (SPW-R) complexes are believed to mediate memory reactivation, transfer, and consolidation. However, their underlying neuronal dynamics at multiple scales remains poorly understood. Using concurrent hippocampal local field potential (LFP) recordings and functional MRI (fMRI), we study local changes in neuronal activity during SPW-R episodes and their brain-wide correlates. Analysis of the temporal alignment between SPW and ripple components reveals well-differentiated SPW-R subtypes in the CA1 LFP. SPW-R-triggered fMRI maps show that ripples aligned to the positive peak of their SPWs have enhanced neocortical metabolic up-regulation. In contrast, ripples occurring at the trough of their SPWs relate to weaker neocortical up-regulation and absent subcortical down-regulation, indicating differentiated involvement of neuromodulatory pathways in the ripple phenomenon mediated by long-range interactions. To our knowledge, this study provides the first evidence for the existence of SPW-R subtypes with differentiated CA1 activity and metabolic correlates in related brain areas, possibly serving different memory functions.
Diversity of sharp-wave–ripple LFP signatures reveals differentiated brain-wide dynamical events
Ramirez-Villegas, Juan F.; Logothetis, Nikos K.; Besserve, Michel
2015-01-01
Sharp-wave–ripple (SPW-R) complexes are believed to mediate memory reactivation, transfer, and consolidation. However, their underlying neuronal dynamics at multiple scales remains poorly understood. Using concurrent hippocampal local field potential (LFP) recordings and functional MRI (fMRI), we study local changes in neuronal activity during SPW-R episodes and their brain-wide correlates. Analysis of the temporal alignment between SPW and ripple components reveals well-differentiated SPW-R subtypes in the CA1 LFP. SPW-R–triggered fMRI maps show that ripples aligned to the positive peak of their SPWs have enhanced neocortical metabolic up-regulation. In contrast, ripples occurring at the trough of their SPWs relate to weaker neocortical up-regulation and absent subcortical down-regulation, indicating differentiated involvement of neuromodulatory pathways in the ripple phenomenon mediated by long-range interactions. To our knowledge, this study provides the first evidence for the existence of SPW-R subtypes with differentiated CA1 activity and metabolic correlates in related brain areas, possibly serving different memory functions. PMID:26540729
Ganchev, Philip; Malehorn, David; Bigbee, William L.; Gopalakrishnan, Vanathi
2013-01-01
We present a novel framework for integrative biomarker discovery from related but separate data sets created in biomarker profiling studies. The framework takes prior knowledge in the form of interpretable, modular rules, and uses them during the learning of rules on a new data set. The framework consists of two methods of transfer of knowledge from source to target data: transfer of whole rules and transfer of rule structures. We evaluated the methods on three pairs of data sets: one genomic and two proteomic. We used standard measures of classification performance and three novel measures of amount of transfer. Preliminary evaluation shows that whole-rule transfer improves classification performance over using the target data alone, especially when there is more source data than target data. It also improves performance over using the union of the data sets. PMID:21571094
NASA Astrophysics Data System (ADS)
Xie, Yushu; Li, Fatao
2010-06-01
The objective of this paper is to study thermal inertia effect due to the fact of the properties of the hyperbolic equations based on LS theory in generalized thermoelasticity. Simulations in a 2D hollow cylinder for uncoupled dynamic thermal stresses and thermal displacements were predicted by use of finite element method with Newmark algorithm. The thermal inertia effect on LS theory in rapid transient heat transfer process is also investigated in comparison with in steady heat transfer process. When different specific heat capacity is chosen, dynamic thermal stresses appear different types of vibration, in which less heat capacity causes more violent dynamic thermal stresses because of the thermal inertia effect. Both dynamic thermal stresses and thermal displacements in rapid transient heat transfer process have the larger amplitude and higher frequency than in steady heat transfer process due to thermal inertia from the results of simulation, which is consistent with the nature of the generalized thermoelasticity.
Dynamical ion transfer between coupled Coulomb crystals in a double-well potential.
Klumpp, Andrea; Zampetaki, Alexandra; Schmelcher, Peter
2017-09-01
We investigate the nonequilibrium dynamics of coupled Coulomb crystals of different sizes trapped in a double well potential. The dynamics is induced by an instantaneous quench of the potential barrier separating the two crystals. Due to the intra- and intercrystal Coulomb interactions and the asymmetric population of the potential wells, we observe a complex reordering of ions within the two crystals as well as ion transfer processes from one well to the other. The study and analysis of the latter processes constitutes the main focus of this work. In particular, we examine the dependence of the observed ion transfers on the quench amplitude performing an analysis for different crystalline configurations ranging from one-dimensional ion chains via two-dimensional zigzag chains and ring structures to three-dimensional spherical structures. Such an analysis provides us with the means to extract the general principles governing the ion transfer dynamics and we gain some insight on the structural disorder caused by the quench of the barrier height.
NASA Astrophysics Data System (ADS)
Huang, Chong; Radabaugh, Jeffrey P.; Aouad, Rony K.; Lin, Yu; Gal, Thomas J.; Patel, Amit B.; Valentino, Joseph; Shang, Yu; Yu, Guoqiang
2016-02-01
Head and neck cancer accounts for 3 to 5% of all cancers in the United States. Primary or salvage surgeries are extensive and often lead to major head and neck defects that require complex reconstructions with local, regional, or free tissue transfer flaps. Knowledge of tissue blood flow (BF) changes after free tissue transfer may enable surgeons to predict the failure of flap thrombosis at an early stage. This study used our recently developed noncontact diffuse correlation spectroscopy to monitor dynamic BF changes in free flaps without getting in contact with the targeted tissue. Eight free flaps were elevated in patients with head and neck cancer; one of the flaps failed. Multiple BF measurements probing the transferred tissue were performed during and post the surgical operation. Postoperative BF values were normalized to the intraoperative baselines (assigning '1') for the calculation of relative BF change (rBF). The rBF changes over the seven successful flaps were 1.89 +/- 0.15, 2.26 +/- 0.13, and 2.43 +/- 0.13 (mean +/- standard error) respectively on postoperative days 2, 4, and 7. These postoperative values were significantly higher than the intraoperative baseline values (p < 0.001), indicating a gradual recovery of flap vascularity after the tissue transfer. By contrast, rBF changes observed from the unsuccessful flap were 1.14 and 1.34 respectively on postoperative days 2 and 4, indicating a less flow recovery. Measurement of BF recovery after flap anastomosis holds the potential to act early to salvage ischemic flaps.
Duan, Xian-Chun; Wang, Yong-Zhong; Zhang, Jun-Ru; Luo, Huan; Zhang, Heng; Xia, Lun-Zhu
2011-08-01
To establish a dynamics model for extracting the lipophilic components in Panax notoginseng with supercritical carbon dioxide (CO2). Based on the theory of counter-flow mass transfer and the molecular mass transfer between the material and the supercritical CO2 fluid under differential mass-conservation equation, a dynamics model was established and computed to compare forecasting result with the experiment process. A dynamics model has been established for supercritical CO2 to extract the lipophilic components in Panax notoginseng, the computed result of this model was consistent with the experiment process basically. The supercritical fluid extract dynamics model established in this research can expound the mechanism in the extract process of which lipophilic components of Panax notoginseng dissolve the mass transfer and is tallied with the actual extract process. This provides certain instruction for the supercritical CO2 fluid extract' s industrialization enlargement.
Dementia knowledge transfer project in a rural area.
Stark, C; Innes, A; Szymczynska, P; Forrest, L; Proctor, K
2013-01-01
Rural Scotland has an ageing population. There has been an increase in the number of people with dementia and as the proportion of people aged over 75 years continues to rise, this will increase still further. The Scottish Government has produced a dementia strategy and implementing this will be a challenge for rural Scotland. Transferring academic knowledge into practice is challenging. A Knowledge Transfer Partnership was formed between NHS Highland and the University of Stirling. A literature review was undertaken of the rural dementia literature; local services were surveyed and described; and interviews were undertaken with people with dementia and carers. Work was conducted on training, diagnostic service provision and local policy. Throughout the project, a collaborative approach was used, which aimed at the joint production of knowledge. Involving University staff in local service development had a substantial impact. Reviewing existing research knowledge and setting it in the context of local services, and of experience of service use, allowed the relevant priorities to be identified. As well as identifying training needs and providing training, the work influenced local decisions on diagnostic service design and standards, and on policy. This embedded engagement model appeared to produce more rapid change than traditional models of use of academic knowledge.
The role of collective motion in the ultrafast charge transfer in van der Waals heterostructures
Wang, Han; Bang, Junhyeok; Sun, Yiyang; ...
2016-05-10
Here, the success of van der Waals (vdW) heterostructures, made of graphene, metal dichalcogenides, and other layered materials, hinges on the understanding of charge transfer across the interface as the foundation for new device concepts and applications. In contrast to conventional heterostructures, where a strong interfacial coupling is essential to charge transfer, recent experimental findings indicate that vdW heterostructues can exhibit ultra-fast charge transfer despite the weak binding of the heterostructure. Using time-dependent density functional theory molecular dynamics, we identify a strong dynamic coupling between the vdW layers associated with charge transfer. This dynamic coupling results in rapid nonlinear coherentmore » charge oscillations which constitute a purely electronic phenomenon and are shown to be a general feature of vdW heterostructures provided they have a critical minimum dipole coupling. Application to MoS2/WS2 heterostructure yields good agreement with experiment, indicating near complete charge transfer within a timescale of 100 fs.The success of van der Waals heterostructures made of graphene, metal dichalcogenides and other layered materials, hinges on the understanding of charge transfer across the interface as the foundation for new device concepts and applications. In contrast to conventional heterostructures, where a strong interfacial coupling is essential to charge transfer, recent experimental findings indicate that van der Waals heterostructues can exhibit ultrafast charge transfer despite the weak binding of these heterostructures. Here we find, using time-dependent density functional theory molecular dynamics, that the collective motion of excitons at the interface leads to plasma oscillations associated with optical excitation. By constructing a simple model of the van der Waals heterostructure, we show that there exists an unexpected criticality of the oscillations, yielding rapid charge transfer across the interface. Application to the MoS2/WS2 heterostructure yields good agreement with experiments, indicating near complete charge transfer within a timescale of 100 fs.« less
The role of collective motion in the ultrafast charge transfer in van der Waals heterostructures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Han; Bang, Junhyeok; Sun, Yiyang
Here, the success of van der Waals (vdW) heterostructures, made of graphene, metal dichalcogenides, and other layered materials, hinges on the understanding of charge transfer across the interface as the foundation for new device concepts and applications. In contrast to conventional heterostructures, where a strong interfacial coupling is essential to charge transfer, recent experimental findings indicate that vdW heterostructues can exhibit ultra-fast charge transfer despite the weak binding of the heterostructure. Using time-dependent density functional theory molecular dynamics, we identify a strong dynamic coupling between the vdW layers associated with charge transfer. This dynamic coupling results in rapid nonlinear coherentmore » charge oscillations which constitute a purely electronic phenomenon and are shown to be a general feature of vdW heterostructures provided they have a critical minimum dipole coupling. Application to MoS2/WS2 heterostructure yields good agreement with experiment, indicating near complete charge transfer within a timescale of 100 fs.The success of van der Waals heterostructures made of graphene, metal dichalcogenides and other layered materials, hinges on the understanding of charge transfer across the interface as the foundation for new device concepts and applications. In contrast to conventional heterostructures, where a strong interfacial coupling is essential to charge transfer, recent experimental findings indicate that van der Waals heterostructues can exhibit ultrafast charge transfer despite the weak binding of these heterostructures. Here we find, using time-dependent density functional theory molecular dynamics, that the collective motion of excitons at the interface leads to plasma oscillations associated with optical excitation. By constructing a simple model of the van der Waals heterostructure, we show that there exists an unexpected criticality of the oscillations, yielding rapid charge transfer across the interface. Application to the MoS2/WS2 heterostructure yields good agreement with experiments, indicating near complete charge transfer within a timescale of 100 fs.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schmieder, R.W.
The author presents a new approach for modeling the dynamics of collections of objects with internal structure. Based on the fact that the behavior of an individual in a population is modified by its knowledge of other individuals, a procedure for accounting for knowledge in a population of interacting objects is presented. It is assumed that each object has partial (or complete) knowledge of some (or all) other objects in the population. The dynamical equations for the objects are then modified to include the effects of this pairwise knowledge. This procedure has the effect of projecting out what the populationmore » will do from the much larger space of what it could do, i.e., filtering or smoothing the dynamics by replacing the complex detailed physical model with an effective model that produces the behavior of interest. The procedure therefore provides a minimalist approach for obtaining emergent collective behavior. The use of knowledge as a dynamical quantity, and its relationship to statistical mechanics, thermodynamics, information theory, and cognition microstructure are discussed.« less
Lost in Knowledge Translation: Time for a Map?
ERIC Educational Resources Information Center
Graham, Ian D.; Logan, Jo; Harrison, Margaret B.; Straus, Sharon E.; Tetroe, Jacqueline; Caswell, Wenda; Robinson, Nicole
2006-01-01
There is confusion and misunderstanding about the concepts of knowledge translation, knowledge transfer, knowledge exchange, research utilization, implementation, diffusion, and dissemination. We review the terms and definitions used to describe the concept of moving knowledge into action. We also offer a conceptual framework for thinking about…
Ouyang, Wenjun; Subotnik, Joseph E
2017-05-07
Using the Anderson-Holstein model, we investigate charge transfer dynamics between a molecule and a metal surface for two extreme cases. (i) With a large barrier, we show that the dynamics follow a single exponential decay as expected; (ii) without any barrier, we show that the dynamics are more complicated. On the one hand, if the metal-molecule coupling is small, single exponential dynamics persist. On the other hand, when the coupling between the metal and the molecule is large, the dynamics follow a biexponential decay. We analyze the dynamics using the Smoluchowski equation, develop a simple model, and explore the consequences of biexponential dynamics for a hypothetical cyclic voltammetry experiment.
Alignment of dynamic networks.
Vijayan, V; Critchlow, D; Milenkovic, T
2017-07-15
Network alignment (NA) aims to find a node mapping that conserves similar regions between compared networks. NA is applicable to many fields, including computational biology, where NA can guide the transfer of biological knowledge from well- to poorly-studied species across aligned network regions. Existing NA methods can only align static networks. However, most complex real-world systems evolve over time and should thus be modeled as dynamic networks. We hypothesize that aligning dynamic network representations of evolving systems will produce superior alignments compared to aligning the systems' static network representations, as is currently done. For this purpose, we introduce the first ever dynamic NA method, DynaMAGNA ++. This proof-of-concept dynamic NA method is an extension of a state-of-the-art static NA method, MAGNA++. Even though both MAGNA++ and DynaMAGNA++ optimize edge as well as node conservation across the aligned networks, MAGNA++ conserves static edges and similarity between static node neighborhoods, while DynaMAGNA++ conserves dynamic edges (events) and similarity between evolving node neighborhoods. For this purpose, we introduce the first ever measure of dynamic edge conservation and rely on our recent measure of dynamic node conservation. Importantly, the two dynamic conservation measures can be optimized with any state-of-the-art NA method and not just MAGNA++. We confirm our hypothesis that dynamic NA is superior to static NA, on synthetic and real-world networks, in computational biology and social domains. DynaMAGNA++ is parallelized and has a user-friendly graphical interface. http://nd.edu/∼cone/DynaMAGNA++/ . tmilenko@nd.edu. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com
Vijayan, V.; Critchlow, D.; Milenković, T.
2017-01-01
Abstract Motivation: Network alignment (NA) aims to find a node mapping that conserves similar regions between compared networks. NA is applicable to many fields, including computational biology, where NA can guide the transfer of biological knowledge from well- to poorly-studied species across aligned network regions. Existing NA methods can only align static networks. However, most complex real-world systems evolve over time and should thus be modeled as dynamic networks. We hypothesize that aligning dynamic network representations of evolving systems will produce superior alignments compared to aligning the systems’ static network representations, as is currently done. Results: For this purpose, we introduce the first ever dynamic NA method, DynaMAGNA ++. This proof-of-concept dynamic NA method is an extension of a state-of-the-art static NA method, MAGNA++. Even though both MAGNA++ and DynaMAGNA++ optimize edge as well as node conservation across the aligned networks, MAGNA++ conserves static edges and similarity between static node neighborhoods, while DynaMAGNA++ conserves dynamic edges (events) and similarity between evolving node neighborhoods. For this purpose, we introduce the first ever measure of dynamic edge conservation and rely on our recent measure of dynamic node conservation. Importantly, the two dynamic conservation measures can be optimized with any state-of-the-art NA method and not just MAGNA++. We confirm our hypothesis that dynamic NA is superior to static NA, on synthetic and real-world networks, in computational biology and social domains. DynaMAGNA++ is parallelized and has a user-friendly graphical interface. Availability and implementation: http://nd.edu/∼cone/DynaMAGNA++/. Contact: tmilenko@nd.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:28881980
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shakib, Farnaz A.; Hanna, Gabriel, E-mail: gabriel.hanna@ualberta.ca
In a previous study [F. A. Shakib and G. Hanna, J. Chem. Phys. 141, 044122 (2014)], we investigated a model proton-coupled electron transfer (PCET) reaction via the mixed quantum-classical Liouville (MQCL) approach and found that the trajectories spend the majority of their time on the mean of two coherently coupled adiabatic potential energy surfaces. This suggested a need for mean surface evolution to accurately simulate observables related to ultrafast PCET processes. In this study, we simulate the time-dependent populations of the three lowest adiabatic states in the ET-PT (i.e., electron transfer preceding proton transfer) version of the same PCET modelmore » via the MQCL approach and compare them to the exact quantum results and those obtained via the fewest switches surface hopping (FSSH) approach. We find that the MQCL population profiles are in good agreement with the exact quantum results and show a significant improvement over the FSSH results. All of the mean surfaces are shown to play a direct role in the dynamics of the state populations. Interestingly, our results indicate that the population transfer to the second-excited state can be mediated by dynamics on the mean of the ground and second-excited state surfaces, as part of a sequence of nonadiabatic transitions that bypasses the first-excited state surface altogether. This is made possible through nonadiabatic transitions between different mean surfaces, which is the manifestation of coherence transfer in MQCL dynamics. We also investigate the effect of the strength of the coupling between the proton/electron and the solvent coordinate on the state population dynamics. Drastic changes in the population dynamics are observed, which can be understood in terms of the changes in the potential energy surfaces and the nonadiabatic couplings. Finally, we investigate the state population dynamics in the PT-ET (i.e., proton transfer preceding electron transfer) and concerted versions of the model. The PT-ET results confirm the participation of all of the mean surfaces, albeit in different proportions compared to the ET-PT case, while the concerted results indicate that the mean of the ground- and first-excited state surfaces only plays a role, due to the large energy gaps between the ground- and second-excited state surfaces.« less
Chen, Xuwei; Yang, Xu; Zeng, Wanying; Wang, Jianhua
2015-08-04
Protein transfer from aqueous medium into ionic liquid is an important approach for the isolation of proteins of interest from complex biological samples. We hereby report a solid-cladding/liquid-core/liquid-cladding sandwich optical waveguide system for the purpose of monitoring the dynamic mass-transfer behaviors of hemoglobin (Hb) at the aqueous/ionic liquid interface. The optical waveguide system is fabricated by using a hydrophobic IL (1,3-dibutylimidazolium hexafluorophosphate, BBimPF6) as the core, and protein solution as one of the cladding layer. UV-vis spectra are recorded with a CCD spectrophotometer via optical fibers. The recorded spectra suggest that the mass transfer of Hb molecules between the aqueous and ionic liquid media involve accumulation of Hb on the aqueous/IL interface followed by dynamic extraction/transfer of Hb into the ionic liquid phase. A part of Hb molecules remain at the interface even after the accomplishment of the extraction/transfer process. Further investigations indicate that the mass transfer of Hb from aqueous medium into the ionic liquid phase is mainly driven by the coordination interaction between heme group of Hb and the cationic moiety of ionic liquid, for example, imidazolium cation in this particular case. In addition, hydrophobic interactions also contribute to the transfer of Hb.
Examination of the Transfer of Astronomy and Space Sciences Knowledge to Daily Life
ERIC Educational Resources Information Center
Emrahoglu, Nuri
2017-01-01
In this study, it was aimed to determine the levels of the ability of science teaching fourth grade students to transfer their knowledge of astronomy and space sciences to daily life within the scope of the Astronomy and Space Sciences lesson. For this purpose, the research method was designed as the mixed method including both the quantitative…
ERIC Educational Resources Information Center
de la Torre, Eva M.; Agasisti, Tommaso; Perez-Esparrells, Carmen
2017-01-01
This article examines how knowledge transfer (KT) indicators affect analyses on efficiency in the Higher Education sector, taking into account the characteristics of the Higher Education Institutions (HEIs). After revising the concept of third mission as a field for data development and its importance in assessing university performance, we…
Maximizing profits in international technology transfer
NASA Technical Reports Server (NTRS)
Straube, W.
1974-01-01
Maximum profit can be introduced into international technology transfer by observing the following: (1) ethical and open dealing between the parties; (2) maximum knowledge of all facts concerning the technology, the use of the technology, the market, competition, prices, and alternatives; (3) ability to coordinate exports, service, support activities, licensing and cross licensing; and (4) knowledgeable people which put these factors together.
Teaching Learning and Discipleship: Education beyond Knowledge Transfer
ERIC Educational Resources Information Center
Wringe, Colin
2009-01-01
An attempt is made to identify what some have felt to be absent from recent official views as to how curricula and the transfer of knowledge are most performatively to be managed. To this end, particular conceptions of teaching and learning are proposed, and use is made of recent work by George Steiner in elaborating a third variant of the…
ERIC Educational Resources Information Center
Duarte Moleiro Martins, José
2016-01-01
The purpose of this article is to better understand the role of internal stakeholders in subsidiaries of multinational companies (MNCs) in order to offer potential insights into the cross-border transfer of knowledge from those companies' headquarters to their subsidiaries. The focus is upon subsidiaries in developing countries, here Mozambique.…
ERIC Educational Resources Information Center
Harris, Margaret; Chisholm, Colin; Burns, George
2013-01-01
Purpose: The purpose of this paper is to provide a conceptual viewpoint which proposes the use of the post graduate Knowledge Transfer Partnership (KTP) approach to learning in undergraduate education and practice-based training. Design/methodology/approach: This is an examination of the KTP approach and how this could be used effectively in…
ERIC Educational Resources Information Center
Balderrama, Jorge Ines Leon; Lopez, Lydia Venecia Gutierrez; Lafarga, Cuitlahuac Valdez
2013-01-01
Using the results of an empirical study in the State of Sonora, Mexico, this paper reports on an attempt to identify trends and transformations that have taken place in the way knowledge transfer activities are organized and structured in higher education institutions and research centres. The research was designed to provide a characterization of…
ERIC Educational Resources Information Center
Rossi, Federica; Rosli, Ainurul
2015-01-01
The issue of what indicators are most appropriate in order to measure the performance of universities in knowledge transfer (KT) activities remains relatively under-investigated. The main aim of this paper is to identify and discuss the limitations to the current measurements of university-industry KT performance, and propose some directions for…
ERIC Educational Resources Information Center
Orr, Jonathan J.; Hulse-Killacky, Diana
2006-01-01
Concepts of voice, meaning, mutual construction of knowledge, and transfer of learning are presented in this paper as critical ingredients that support the teaching of group work from an ecological perspective. Examples of these concepts are given to illustrate their application in group work classes. (Contains 1 table.)
The Import of Knowledge Export: Connecting Findings and Theories of Transfer of Learning
ERIC Educational Resources Information Center
Day, Samuel B.; Goldstone, Robert L.
2012-01-01
After more than 100 years of interest and study, knowledge transfer remains among the most challenging, contentious, and important issues for both psychology and education. In this article, we review and discuss many of the more important ideas and findings from the existing research and attempt to bridge this body of work with the exciting new…
ERIC Educational Resources Information Center
Shafloot, Fayez M.
2012-01-01
The purpose of this study was to explore human resource (HR) managers' perceptions of training practices (i.e., needs assessment, trainee preparation, training program review, accountability, management support, knowledge transfer, and performance improvement) in Saudi private sector organizations. The research questions were: (1) How do HR…
ERIC Educational Resources Information Center
Lekgoko, Olemme; Winskel, Heather
2008-01-01
The current study investigates how beginner readers learn to read Setswana and English, and whether there is cross-language transference of skills between these two languages. Letter knowledge, phoneme awareness and reading of words and pseudowords in both Setswana and English were assessed in 36 Grade 2 children. A complex pattern emerged.…
ERIC Educational Resources Information Center
Pauen, Sabina; Bechtel-Kuehne, Sabrina
2016-01-01
This report investigates tool learning and its relations to executive functions (EFs) in toddlers. In Study 1 (N = 93), 18-, 20-, 22-, and 24-month-old children learned equally well to choose a correct tool from observation, whereas performance based on feedback improved with age. Knowledge transfer showed significant progress after 22 months of…
Vision for a Global Registry of Anticipated Public Health Studies
Choi, Bernard C.K.; Frank, John; Mindell, Jennifer S.; Orlova, Anna; Lin, Vivian; Vaillancourt, Alain D.M.G.; Puska, Pekka; Pang, Tikki; Skinner, Harvey A.; Marsh, Marsha; Mokdad, Ali H.; Yu, Shun-Zhang; Lindner, M. Cristina; Sherman, Gregory; Barreto, Sandhi M.; Green, Lawrence W.; Svenson, Lawrence W.; Sainsbury, Peter; Yan, Yongping; Zhang, Zuo-Feng; Zevallos, Juan C.; Ho, Suzanne C.; de Salazar, Ligia M.
2007-01-01
In public health, the generation, management, and transfer of knowledge all need major improvement. Problems in generating knowledge include an imbalance in research funding, publication bias, unnecessary studies, adherence to fashion, and undue interest in novel and immediate issues. Impaired generation of knowledge, combined with a dated and inadequate process for managing knowledge and an inefficient system for transferring knowledge, mean a distorted body of evidence available for decisionmaking in public health. This article hopes to stimulate discussion by proposing a Global Registry of Anticipated Public Health Studies. This prospective, comprehensive system for tracking research in public health could help enhance collaboration and improve efficiency. Practical problems must be discussed before such a vision can be further developed. PMID:17413073
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1996-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. Little is also known about the intermediary-based system that is used to transfer the results of federally funded R&D to the U.S. aerospace industry. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports, present a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communication practices of U.S. aerospace engineers and scientists who were members of the American Institute of Aeronautics and Astronautics (AIAA) and identified themselves as educators.
Enhanced nucleon transfer in tip collisions of 238U+124Sn
NASA Astrophysics Data System (ADS)
Sekizawa, Kazuyuki
2017-10-01
Multinucleon transfer processes in low-energy heavy ion reactions have attracted increasing interest in recent years aiming at the production of new neutron-rich isotopes. Clearly, it is an imperative task to further develop understanding of underlying reaction mechanisms to lead experiments to success. In this paper, from systematic time-dependent Hartree-Fock calculations for the 238U+124Sn reaction, it is demonstrated that transfer dynamics depend strongly on the orientations of 238U, quantum shells, and collision energies. Two important conclusions are obtained: (i) Experimentally observed many-proton transfer from 238U to 124Sn can be explained by a multinucleon transfer mechanism governed by enhanced neck evolution in tip collisions; (ii) novel reaction dynamics are observed in tip collisions at energies substantially above the Coulomb barrier, where a number of nucleons are transferred from 124Sn to 238U, producing transuranium nuclei as primary reaction products, which could be a means to synthesize superheavy nuclei. Both results indicate the importance of the neck (shape) evolution dynamics, which are sensitive to orientations, shell effects, and collision energies, for exploring possible pathways to produce new unstable nuclei.
Felicíssimo, V C; Guimarães, F F; Cesar, A; Gel'mukhanov, F; Agren, H
2006-11-30
The theory of IR-X-ray pump-probe spectroscopy beyond the Born-Oppenheimer approximation is developed and applied to the study of the dynamics of intramolecular proton transfer in glyoxalmonoxime leading to the formation of the tautomer 2-nitrosoethenol. Due to the IR pump pulses the molecule gains sufficient energy to promote a proton to a weakly bound well. A femtosecond X-ray pulse snapshots the wave packet route and, hence, the dynamics of the proton transfer. The glyoxalmonoxime molecule contains two chemically nonequivalent oxygen atoms that possess distinct roles in the hydrogen bond, a hydrogen donor and an acceptor. Core ionizations of these form two intersecting core-ionized states, the vibronic coupling between which along the OH stretching mode partially delocalizes the core hole, resulting in a hopping of the core hole from one site to another. This, in turn, affects the dynamics of the proton transfer in the core-ionized state. The quantum dynamical simulations of X-ray photoelectron spectra of glyoxalmonoxime driven by strong IR pulses demonstrate the general applicability of the technique for studies of intramolecular proton transfer in systems with vibronic coupling.
Li, Jingrui; Kondov, Ivan; Wang, Haobin; Thoss, Michael
2015-04-10
A recently developed methodology to simulate photoinduced electron transfer processes at dye-semiconductor interfaces is outlined. The methodology employs a first-principles-based model Hamiltonian and accurate quantum dynamics simulations using the multilayer multiconfiguration time-dependent Hartree approach. This method is applied to study electron injection in the dye-semiconductor system coumarin 343-TiO2. Specifically, the influence of electronic-vibrational coupling is analyzed. Extending previous work, we consider the influence of Dushinsky rotation of the normal modes as well as anharmonicities of the potential energy surfaces on the electron transfer dynamics.
NASA Astrophysics Data System (ADS)
Styers-Barnett, David; Gannon, Erika; Papanikolas, John; Meyer, Thomas
2003-03-01
The energy transfer dynamics between the ^3MLCT excited state of a polypyridyl Ru(II) chromophore and a ligand-bound anthracene has been studied using femtosecond transient absorption spectroscopy. Photoexcitation of the metal complex at 450 nm promotes an electron from a d-orbital on the metal to a π* orbital on the bipyridine, forming a metal-to-ligand charge-transfer (MLCT) excited state. Energy transfer to the covalently appended anthracene is followed by the growth of the anthracene excited state absorption at 425 nm, and the simultaneous decay of the ^3MLCT absorption at 380 nm. The observed growth is biexponential, with the fast component attributed to energy transfer (19 ps), and the slow component arising from a combination of interligand electron transfer between the polypyridyl ligands and energy transfer (75 ps).
Lu, Dawei; Mao, Chenchen; Cho, Suehyun K.; Ahn, Sungmo; Park, Wounjhang
2016-01-01
Energy transfer upconversion (ETU) is known to be the most efficient frequency upconversion mechanism. Surface plasmon can further enhance the upconversion process, opening doors to many applications. However, ETU is a complex process involving competing transitions between multiple energy levels and it has been difficult to precisely determine the enhancement mechanisms. In this paper, we report a systematic study on the dynamics of the ETU process in NaYF4:Yb3+,Er3+ nanoparticles deposited on plasmonic nanograting structure. From the transient near-infrared photoluminescence under various excitation power densities, we observed faster energy transfer rates under stronger excitation conditions until it reached saturation where the highest internal upconversion efficiency was achieved. The experimental data were analyzed using the complete set of rate equations. The internal upconversion efficiency was found to be 56% and 36%, respectively, with and without the plasmonic nanograting. We also analyzed the transient green emission and found that it is determined by the infrared transition rate. To our knowledge, this is the first report of experimentally measured internal upconversion efficiency in plasmon enhanced upconversion material. Our work decouples the internal upconversion efficiency from the overall upconverted luminescence efficiency, allowing more targeted engineering for efficiency improvement. PMID:26739230
Cordaux, Richard; Gilbert, Clément
2017-07-21
An increasing number of horizontal gene transfer (HGT) events from bacteria to animals have been reported in the past years, many of which involve Wolbachia bacterial endosymbionts and their invertebrate hosts. Most transferred Wolbachia genes are neutrally-evolving fossils embedded in host genomes. A remarkable case of Wolbachia HGT for which a clear evolutionary significance has been demonstrated is the " f element", a nuclear Wolbachia insert involved in female sex determination in the terrestrial isopod Armadillidium vulgare . The f element represents an instance of bacteria-to-animal HGT that has occurred so recently that it was possible to infer the donor (feminizing Wolbachia closely related to the w VulC Wolbachia strain of A. vulgare ) and the mechanism of integration (a nearly complete genome inserted by micro-homology-mediated recombination). In this review, we summarize our current knowledge of the f element and discuss arising perspectives regarding female sex determination, unstable inheritance, population dynamics and the molecular evolution of the f element. Overall, the f element unifies three major areas in evolutionary biology: symbiosis, HGT and sex determination. Its characterization highlights the tremendous impact sex ratio distorters can have on the evolution of sex determination mechanisms and sex chromosomes in animals and plants.
Ab Initio Computation of Dynamical Properties: Pressure Broadening
NASA Astrophysics Data System (ADS)
Wiesenfeld, Laurent; Drouin, Brian
2014-06-01
Rotational spectroscopy of polar molecules is the main observational tool in many areas of astrophysics, for gases of low densities (n ˜ 102 - 108 cm-3). Spectral line shapes in astrophysical media are largely dominated by turbulence-induced Doppler effects and natural line broadening are negligible. However line broadening remains an important tool for denser gases, like planetary high atmospheres. Understanding the excitation schemes of polar molecules requires the knowledge of excitation transfer rate due to collisional excitation, between the polar molecule and the ambient gas, usually H2. Transport properties in ionized media also require a precise knowledge of momentum transfer rates by elastic collisions. In order to assess the theoretically computed cross section and energy/momentum transfer rates, direct absolute experiments are scarce. The best way is to measure not individual scattering events but rather the global effect of the buffer gas, thanks to the pressure broadening cross sections, whose magnitude can be measured without any scaling parameters. At low temperatures, both elastic and inelastic scattering amplitudes are tested. At higher temperature, depending on the interaction strength, only inelastic scattering cross section are shown to play a significant role 1 ,2. Thanks to the advances of computer capabilities, it has become practical to compute spectral line parameters fromab initio quantum chemistry. In particular, the theory of rotational line broadening is readily incorporated into scattering quantum dynamical theory, like close-coupling schemes. The only approximations used in the computation are the isolated collision/isolated line approximations. We compute the non-binding interaction potential with high precision quantum chemistry and fit the resulting ab initio points onto a suitable functional. We have recently computed several such systems, for molecules in H2 buffer gas: H2O,3 H2CO,4 HCO+ .5 Detailed computations taking into account the ortho or para state of H2 were performed, at temperatures ranging from 10 K to 100K, typically. Reliable results are found, that compare favorably to experiments. In particular, the water-molecular hydrogen system has been thoroughly computed and successfully experimentally tested 6. New projects consider other simple molecules as well as heavier systems, relevant for cometary comae and planetary high atmospheres. as part of the GNU EPrints system
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1995-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communications practices of U.S. aerospace engineers and scientists who are members of the American Institute of Aeronautics and Astronautics (AIAA).
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally, funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DoD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from two surveys of our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report and close with a brief overview of on-going research into aerospace knowledge diffusion focusing on the role of the industry-affiliated information intermediary.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communications practices of U.S. aerospace engineers and scientists affiliated with the Society of Automotive Engineers (SAE).
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communications practices of British aerospace engineers and scientists.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DoD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis U.S. aerospace industry librarians and technical information specialists as information intermediaries.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1996-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communication practices of U.S. aerospace engineers and scientists who were members of the Society of Manufacturing Engineers.
Evaluation of oxygen transfer rates in stirred-tank bioreactors for clinical manufacturing.
Bellucci, Joseph J; Hamaker, Kent H
2011-01-01
Several methods are available for determining the volumetric oxygen transfer coefficient in bioreactors, though their application in industrial bioprocess has been limited. To be practically useful, mass transfer measurements made in nonfermenting systems must be consistent with observed microbial respiration rates. This report details a procedure for quantifying the relationship between agitation frequency and oxygen transfer rate that was applied in stirred-tank bioreactors used for clinical biologics manufacturing. The intrinsic delay in dissolved oxygen (DO) measurement was evaluated by shifting the bioreactor pressure and fitting a first-order mathematical model to the DO response. The dynamic method was coupled with the DO lag results to determine the oxygen transfer rate in Water for Injection (WFI) and a complete culture medium. A range of agitation frequencies was investigated at a fixed air sparge flow rate, replicating operating conditions used in Pichia pastoris fermentation. Oxygen transfer rates determined by this method were in excellent agreement with off-gas calculations from cultivation of the organism (P = 0.1). Fermentation of Escherichia coli at different operating parameters also produced respiration rates that agreed with the corresponding dynamic method results in WFI (P = 0.02). The consistency of the dynamic method results with the off-gas data suggests that compensation for the delay in DO measurement can be combined with dynamic gassing to provide a practical, viable model of bioreactor oxygen transfer under conditions of microbial fermentation. Copyright © 2011 American Institute of Chemical Engineers (AIChE).
Relationship between femtosecond-picosecond dynamics to enzyme catalyzed H-transfer
Cheatum, Christopher M.; Kohen, Amnon
2015-01-01
At physiological temperatures, enzymes exhibit a broad spectrum of conformations, which interchange via thermally activated dynamics. These conformations are sampled differently in different complexes of the protein and its ligands, and the dynamics of exchange between these conformers depends on the mass of the group that is moving and the length scale of the motion, as well as restrictions imposed by the globular fold of the enzymatic complex. Many of these motions have been examined and their role in the enzyme function illuminated, yet most experimental tools applied so far have identified dynamics at time scales of seconds to nanoseconds, which are much slower than the time scale for H-transfer between two heavy atoms. This chemical conversion and other processes involving cleavage of covalent bonds occur on picosecond to femtosecond time scales, where slower processes mask both the kinetics and dynamics. Here we present a combination of kinetic and spectroscopic methods that may enable closer examination of the relationship between enzymatic C-H→C transfer and the dynamics of the active site environment at the chemically relevant time scale. These methods include kinetic isotope effects and their temperature dependence, which are used to study the kinetic nature of the H-transfer, and 2D IR spectroscopy, which is used to study the dynamics of transition-state- and ground-state-analog complexes. The combination of these tools is likely to provide a new approach to examine the protein dynamics that directly influence the chemical conversion catalyzed by enzymes. PMID:23539379
DOT National Transportation Integrated Search
2014-05-01
Immersive Virtual Learning Environments (IVLEs) are extensively used in training, but few rigorous scientific investigations regarding the : transfer of learning have been conducted. Measurement of learning transfer through evaluative methods is key ...
NASA Astrophysics Data System (ADS)
Drukker, Karen; Hammes-Schiffer, Sharon
1997-07-01
This paper presents an analytical derivation of a multiconfigurational self-consistent-field (MC-SCF) solution of the time-independent Schrödinger equation for nuclear motion (i.e. vibrational modes). This variational MC-SCF method is designed for the mixed quantum/classical molecular dynamics simulation of multiple proton transfer reactions, where the transferring protons are treated quantum mechanically while the remaining degrees of freedom are treated classically. This paper presents a proof that the Hellmann-Feynman forces on the classical degrees of freedom are identical to the exact forces (i.e. the Pulay corrections vanish) when this MC-SCF method is used with an appropriate choice of basis functions. This new MC-SCF method is applied to multiple proton transfer in a protonated chain of three hydrogen-bonded water molecules. The ground state and the first three excited state energies and the ground state forces agree well with full configuration interaction calculations. Sample trajectories are obtained using adiabatic molecular dynamics methods, and nonadiabatic effects are found to be insignificant for these sample trajectories. The accuracy of the excited states will enable this MC-SCF method to be used in conjunction with nonadiabatic molecular dynamics methods. This application differs from previous work in that it is a real-time quantum dynamical nonequilibrium simulation of multiple proton transfer in a chain of water molecules.
Cumulative and Segmented Learning: Exploring the Role of Curriculum Structures in Knowledge-Building
ERIC Educational Resources Information Center
Maton, Karl
2009-01-01
The present article extends Basil Bernstein's theorisation of "discourses" and "knowledge structures" to explore the potential of educational knowledge structures to enable or constrain cumulative learning, where students can transfer knowledge across contexts and build knowledge over time. It offers a means of overcoming…
Knowledge Acquisition, Knowledge Programming, and Knowledge Refinement.
ERIC Educational Resources Information Center
Hayes-Roth, Frederick; And Others
This report describes the principal findings and recommendations of a 2-year Rand research project on machine-aided knowledge acquisition and discusses the transfer of expertise from humans to machines, as well as the functions of planning, debugging, knowledge refinement, and autonomous machine learning. The relative advantages of humans and…
Analysis on the Management of College Teachers' Tacit Knowledge
ERIC Educational Resources Information Center
Zhang, Linying; Han, Zhijun
2008-01-01
Knowledge management, especially, tacit knowledge management, is a significant guarantee for the sustainable development of universities. The transfer of college teachers' tacit knowledge is the key and difficult point in tacit knowledge management of universities. This paper starts from the existence and application condition of college teachers'…
Border Crossing Knowledge Systems: A PNG Teacher's Autoethnography
ERIC Educational Resources Information Center
Reta, Medi
2010-01-01
Narratives have always been integral to Indigenous knowledge transfer. In this autoethnography the author shares her border crossings between her Indigenous knowledge systems and the often dominant Western knowledge system. Pertinent to these experiences are the stark contrasts that exist between the two knowledge systems and their educational…
Verhagen, Evert; Voogt, Nelly; Bruinsma, Anja; Finch, Caroline F
2014-04-01
Evidence of effectiveness does not equal successful implementation. To progress the field, practical tools are needed to bridge the gap between research and practice and to truly unite effectiveness and implementation evidence. This paper describes the Knowledge Transfer Scheme integrating existing implementation research frameworks into a tool which has been developed specifically to bridge the gap between knowledge derived from research on the one side and evidence-based usable information and tools for practice on the other.
Science to Policy: Many Roads to Travel (Invited)
NASA Astrophysics Data System (ADS)
Eriksson, S. C.; McCaughey, J.
2013-12-01
Transferring scientific discoveries to policies and their implementation is not a narrow, one-way road. The complexities of policy-making are not normally within the purview of either scientists or science educators and communicators. Politics, bureaucracy, economics, culture, religion, and local knowledge are a few areas that help determine how policies are made. These factors are compounded by differences in cultures among scientists, educators/communicators, and governments. To complicate this further, bodies of knowledge which could be brought to bear upon improved policies and implementation lie within different disciplines, e.g. natural sciences, disaster risk reduction, development, psychology, social science, communications, education and more. In a scientific research institution, we have found many potential paths to help transfer knowledge back and forth between scientists and decision-makers. Some of these paths are short with an end in sight. Others are longer, and the destination can't be seen. Some of these paths include a) education and discussion with various government agencies, b) educating students who will return to various agencies and educational institutions in their home countries, c) sharing scientific knowledge with research colleagues, d) consulting, e) working with NGOs, and media, f) working with colleagues in other fields, e.g. development, risk, regional consortia. Recognizing and transferring knowledge among different disciplines, learning the needs of various players, finding the most productive paths, and thinking about varying time frames are important in prioritizing the transference of science into action.
The relationship between recollection, knowledge transfer, and student attitudes towards chemistry
NASA Astrophysics Data System (ADS)
Odeleye, Oluwatobi Omobonike
Certain foundational concepts, including acid-base theory, chemical bonding and intermolecular forces (IMFs), appear throughout the undergraduate chemistry curriculum. The level of understanding of these foundational concepts influences the ability of students to recognize the relationships between sub-disciplines in chemistry. The purpose of this study was to investigate the relationship between student attitudes towards chemistry and their abilities to recollect and transfer knowledge of IMFs, a foundational concept, to their daily lives as well as to other classes. Data were collected using surveys, interviews and classroom observations, and analyzed using qualitative methods. The data show that while most students were able to function at lower levels of thinking by providing a definition of IMFs, majority were unable to function at higher levels of thinking as evidenced by their inability to apply their knowledge of IMFs to their daily lives and other classes. The results of this study suggest a positive relationship between students' abilities to recollect knowledge and their abilities to transfer that knowledge. The results also suggest positive relationships between recollection abilities of students and their attitudes towards chemistry as well as their transfer abilities and attitudes towards chemistry. Recommendations from this study include modifications of pedagogical techniques in ways that facilitate higher-level thinking and emphasize how chemistry applies not only to daily life, but also to other courses.
Applications of Multi-Body Dynamical Environments: The ARTEMIS Transfer Trajectory Design
NASA Technical Reports Server (NTRS)
Folta, David C.; Woodard, Mark; Howell, Kathleen; Patterson, Chris; Schlei, Wayne
2010-01-01
The application of forces in multi-body dynamical environments to pennit the transfer of spacecraft from Earth orbit to Sun-Earth weak stability regions and then return to the Earth-Moon libration (L1 and L2) orbits has been successfully accomplished for the first time. This demonstrated transfer is a positive step in the realization of a design process that can be used to transfer spacecraft with minimal Delta-V expenditures. Initialized using gravity assists to overcome fuel constraints; the ARTEMIS trajectory design has successfully placed two spacecraft into EarthMoon libration orbits by means of these applications.
Vakorin, Vasily A.; Mišić, Bratislav; Krakovska, Olga; McIntosh, Anthony Randal
2011-01-01
Variability in source dynamics across the sources in an activated network may be indicative of how the information is processed within a network. Information-theoretic tools allow one not only to characterize local brain dynamics but also to describe interactions between distributed brain activity. This study follows such a framework and explores the relations between signal variability and asymmetry in mutual interdependencies in a data-driven pipeline of non-linear analysis of neuromagnetic sources reconstructed from human magnetoencephalographic (MEG) data collected as a reaction to a face recognition task. Asymmetry in non-linear interdependencies in the network was analyzed using transfer entropy, which quantifies predictive information transfer between the sources. Variability of the source activity was estimated using multi-scale entropy, quantifying the rate of which information is generated. The empirical results are supported by an analysis of synthetic data based on the dynamics of coupled systems with time delay in coupling. We found that the amount of information transferred from one source to another was correlated with the difference in variability between the dynamics of these two sources, with the directionality of net information transfer depending on the time scale at which the sample entropy was computed. The results based on synthetic data suggest that both time delay and strength of coupling can contribute to the relations between variability of brain signals and information transfer between them. Our findings support the previous attempts to characterize functional organization of the activated brain, based on a combination of non-linear dynamics and temporal features of brain connectivity, such as time delay. PMID:22131968
Chemical dynamics of the first proton-coupled electron transfer of water oxidation on TiO2 anatase.
Chen, Jia; Li, Ye-Fei; Sit, Patrick; Selloni, Annabella
2013-12-18
Titanium dioxide (TiO2) is a prototype, water-splitting (photo)catalyst, but its performance is limited by the large overpotential for the oxygen evolution reaction (OER). We report here a first-principles density functional theory study of the chemical dynamics of the first proton-coupled electron transfer (PCET), which is considered responsible for the large OER overpotential on TiO2. We use a periodic model of the TiO2/water interface that includes a slab of anatase TiO2 and explicit water molecules, sample the solvent configurations by first principles molecular dynamics, and determine the energy profiles of the two electronic states involved in the electron transfer (ET) by hybrid functional calculations. Our results suggest that the first PCET is sequential, with the ET following the proton transfer. The ET occurs via an inner sphere process, which is facilitated by a state in which one electronic hole is shared by the two oxygen ions involved in the transfer.
NASA Astrophysics Data System (ADS)
Murphy, Glen; Salomone, Sonia
2013-03-01
While highly cohesive groups are potentially advantageous they are also often correlated with the emergence of knowledge and information silos based around those same functional or occupational clusters. Consequently, an essential challenge for engineering organisations wishing to overcome informational silos is to implement mechanisms that facilitate, encourage and sustain interactions between otherwise disconnected groups. This paper acts as a primer for those seeking to gain an understanding of the design, functionality and utility of a suite of software tools generically termed social media technologies in the context of optimising the management of tacit engineering knowledge. Underpinned by knowledge management theory and using detailed case examples, this paper explores how social media technologies achieve such goals, allowing for the transfer of knowledge by tapping into the tacit and explicit knowledge of disparate groups in complex engineering environments.
Revealing the Dynamics of Thylakoid Membranes in Living Cyanobacterial Cells
Stingaciu, Laura-Roxana; O’Neill, Hugh; Liberton, Michelle; ...
2016-01-21
Cyanobacteria are photosynthetic prokaryotes that make major contributions to the production of the oxygen in the Earth atmosphere. The photosynthetic machinery in cyanobacterial cells is housed in flattened membrane structures called thylakoids. The structural organization of cyanobacterial cells and the arrangement of the thylakoid membranes in response to environmental conditions have been widely investigated. However, there is limited knowledge about the internal dynamics of these membranes in terms of their flexibility and motion during the photosynthetic process. Here, we present a direct observation of thylakoid membrane undulatory motion in vivo and show a connection between membrane mobility and photosynthetic activity.more » High-resolution inelastic neutron scattering experiments on the cyanobacterium Synechocystis sp. PCC 6803 assessed the flexibility of cyanobacterial thylakoid membrane sheets and the dependence of the membranes on illumination conditions. Moreover, we observed softer thylakoid membranes in the dark that have three-to four fold excess mobility compared to membranes under high light conditions. Finally, our analysis indicates that electron transfer between photosynthetic reaction centers and the associated electrochemical proton gradient across the thylakoid membrane result in a significant driving force for excess membrane dynamics. These observations provide a deeper understanding of the relationship between photosynthesis and cellular architecture.« less
Revealing the Dynamics of Thylakoid Membranes in Living Cyanobacterial Cells
NASA Astrophysics Data System (ADS)
Stingaciu, Laura-Roxana; O'Neill, Hugh; Liberton, Michelle; Urban, Volker S.; Pakrasi, Himadri B.; Ohl, Michael
2016-01-01
Cyanobacteria are photosynthetic prokaryotes that make major contributions to the production of the oxygen in the Earth atmosphere. The photosynthetic machinery in cyanobacterial cells is housed in flattened membrane structures called thylakoids. The structural organization of cyanobacterial cells and the arrangement of the thylakoid membranes in response to environmental conditions have been widely investigated. However, there is limited knowledge about the internal dynamics of these membranes in terms of their flexibility and motion during the photosynthetic process. We present a direct observation of thylakoid membrane undulatory motion in vivo and show a connection between membrane mobility and photosynthetic activity. High-resolution inelastic neutron scattering experiments on the cyanobacterium Synechocystis sp. PCC 6803 assessed the flexibility of cyanobacterial thylakoid membrane sheets and the dependence of the membranes on illumination conditions. We observed softer thylakoid membranes in the dark that have three-to four fold excess mobility compared to membranes under high light conditions. Our analysis indicates that electron transfer between photosynthetic reaction centers and the associated electrochemical proton gradient across the thylakoid membrane result in a significant driving force for excess membrane dynamics. These observations provide a deeper understanding of the relationship between photosynthesis and cellular architecture.
Designing Tasks to Promote and Assess Mathematical Transfer in Primary School Children
ERIC Educational Resources Information Center
Clark, Julie; Page, Shaileigh; Thornton, Steve
2013-01-01
This study aims to design learning situations and tasks that promote and assess the capacity of primary school children to transfer mathematical knowledge to new contexts. We discuss previous studies investigating mathematical transfer, and particularly the strengths and limitations of tasks used to assess transfer in these studies. We describe…
Transfer of Learning Transformed
ERIC Educational Resources Information Center
Larsen-Freeman, Diane
2013-01-01
Instruction is motivated by the assumption that students can transfer their learning, or apply what they have learned in school to another setting. A common problem arises when the expected transfer does not take place, what has been referred to as the inert knowledge problem. More than an academic inconvenience, the failure to transfer is a major…
Understanding Transfer as Personal Change: Concerns, Intentions, and Resistance
ERIC Educational Resources Information Center
Young, Jeani C.
2013-01-01
Adult education is about change. Change in knowledge and understanding. Change in attitudes and beliefs. Change in skills and behaviors. The transfer that adult educators and learners often want to achieve is that change. In situations where transfer equals change, models of change can be useful to describe, support, and predict transfer. This…
Keßberg, Anton; Lübken, Tilo; Metz, Peter
2018-05-02
A concise and highly enantioselective synthesis of structurally diverse isoflavans from a single chromone is described. The key transformation is a single-step conversion of racemic isoflavanones into virtually enantiopure isoflavans by domino asymmetric transfer hydrogenation/deoxygenation with dynamic kinetic resolution.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Deur, Alexandre; Brodsky, Stanley J.; de Téramond, Guy F.
Here, we review present knowledge onmore » $$\\alpha_{s}$$, the Quantum Chromodynamics (QCD) running coupling. The dependence of $$\\alpha_s(Q^2)$$ on momentum transfer $Q$ encodes the underlying dynamics of hadron physics --from color confinement in the infrared domain to asymptotic freedom at short distances. We will survey our present theoretical and empirical knowledge of $$\\alpha_s(Q^2)$$, including constraints at high $Q^2$ predicted by perturbative QCD, and constraints at small $Q^2$ based on models of nonperturbative dynamics. In the first, introductory, part of this review, we explain the phenomenological meaning of the coupling, the reason for its running, and the challenges facing a complete understanding of its analytic behavior in the infrared domain. In the second, more technical, part of the review, we discuss $$\\alpha_s(Q^2)$$ in the high momentum transfer domain of QCD. We review how $$\\alpha_s$$ is defined, including its renormalization scheme dependence, the definition of its renormalization scale, the utility of effective charges, as well as `` Commensurate Scale Relations" which connect the various definitions of the QCD coupling without renormalization scale ambiguity. We also report recent important experimental measurements and advanced theoretical analyses which have led to precise QCD predictions at high energy. As an example of an important optimization procedure, we discuss the ``Principle of Maximum Conformality" which enhances QCD's predictive power by removing the dependence of the predictions for physical observables on the choice of the gauge and renormalization scheme. In last part of the review, we discuss $$\\alpha_s(Q^2)$$ in the low momentum transfer domain, where there has been no consensus on how to define $$\\alpha_s(Q^2)$$ or its analytic behavior. We will discuss the various approaches used for low energy calculations. Among them, we will discuss the light-front holographic approach to QCD in the strongly coupled regime and its prediction for the analytic form of $$\\alpha_s(Q^2)$$. The AdS/QCD light-front holographic analysis predicts the color confinement potential underlying hadron spectroscopy and dynamics, and it gives a remarkable connection between the perturbative QCD scale $$\\Lambda$$ and hadron masses. One can also identify a specific scale $$Q_0$$ which demarcates the division between perturbative and nonperturbative QCD. We also review other important methods for computing the QCD coupling, including Lattice QCD, Schwinger-Dyson equations and the Gribov-Zwanziger analysis. After describing these approaches and enumerating conflicting results, we provide a partial discussion on the origin of these discrepancies and how to remedy them. Our aim is not only to review the advances on this difficult subject, but also to suggest what could be the best definition of $$\\alpha_s(Q^2)$$ in order to bring better unity to the subject.« less
Deur, Alexandre; Brodsky, Stanley J.; de Téramond, Guy F.
2016-05-09
Here, we review present knowledge onmore » $$\\alpha_{s}$$, the Quantum Chromodynamics (QCD) running coupling. The dependence of $$\\alpha_s(Q^2)$$ on momentum transfer $Q$ encodes the underlying dynamics of hadron physics --from color confinement in the infrared domain to asymptotic freedom at short distances. We will survey our present theoretical and empirical knowledge of $$\\alpha_s(Q^2)$$, including constraints at high $Q^2$ predicted by perturbative QCD, and constraints at small $Q^2$ based on models of nonperturbative dynamics. In the first, introductory, part of this review, we explain the phenomenological meaning of the coupling, the reason for its running, and the challenges facing a complete understanding of its analytic behavior in the infrared domain. In the second, more technical, part of the review, we discuss $$\\alpha_s(Q^2)$$ in the high momentum transfer domain of QCD. We review how $$\\alpha_s$$ is defined, including its renormalization scheme dependence, the definition of its renormalization scale, the utility of effective charges, as well as `` Commensurate Scale Relations" which connect the various definitions of the QCD coupling without renormalization scale ambiguity. We also report recent important experimental measurements and advanced theoretical analyses which have led to precise QCD predictions at high energy. As an example of an important optimization procedure, we discuss the ``Principle of Maximum Conformality" which enhances QCD's predictive power by removing the dependence of the predictions for physical observables on the choice of the gauge and renormalization scheme. In last part of the review, we discuss $$\\alpha_s(Q^2)$$ in the low momentum transfer domain, where there has been no consensus on how to define $$\\alpha_s(Q^2)$$ or its analytic behavior. We will discuss the various approaches used for low energy calculations. Among them, we will discuss the light-front holographic approach to QCD in the strongly coupled regime and its prediction for the analytic form of $$\\alpha_s(Q^2)$$. The AdS/QCD light-front holographic analysis predicts the color confinement potential underlying hadron spectroscopy and dynamics, and it gives a remarkable connection between the perturbative QCD scale $$\\Lambda$$ and hadron masses. One can also identify a specific scale $$Q_0$$ which demarcates the division between perturbative and nonperturbative QCD. We also review other important methods for computing the QCD coupling, including Lattice QCD, Schwinger-Dyson equations and the Gribov-Zwanziger analysis. After describing these approaches and enumerating conflicting results, we provide a partial discussion on the origin of these discrepancies and how to remedy them. Our aim is not only to review the advances on this difficult subject, but also to suggest what could be the best definition of $$\\alpha_s(Q^2)$$ in order to bring better unity to the subject.« less
DOT National Transportation Integrated Search
2014-05-01
mmersive Virtual Learning Environments (IVLEs) are extensively used in training, but few rigorous scienti c investigations regarding : the transfer of learning have been conducted. Measurement of learning transfer through evaluative methods is key...
Hosseini, Mohammad; Jiang, Yu; Wu, Poliang; Berlin, Richard B; Ren, Shangping; Sha, Lui
2016-11-01
There is a great divide between rural and urban areas, particularly in medical emergency care. Although medical best practice guidelines exist and are in hospital handbooks, they are often lengthy and difficult to apply clinically. The challenges are exaggerated for doctors in rural areas and emergency medical technicians (EMT) during patient transport. In this paper, we propose the concept of distributed executable medical best practice guidance systems to assist adherence to best practice from the time that a patient first presents at a rural hospital, through diagnosis and ambulance transfer to arrival and treatment at a regional tertiary hospital center. We codify complex medical knowledge in the form of simplified distributed executable disease automata, from the thin automata at rural hospitals to the rich automata in the regional center hospitals. However, a main challenge is how to efficiently and safely synchronize distributed best practice models as the communication among medical facilities, devices, and professionals generates a large number of messages. This complex problem of patient diagnosis and transport from rural to center facility is also fraught with many uncertainties and changes resulting in a high degree of dynamism. A critically ill patient's medical conditions can change abruptly in addition to changes in the wireless bandwidth during the ambulance transfer. Such dynamics have yet to be addressed in existing literature on telemedicine. To address this situation, we propose a pathophysiological model-driven message exchange communication architecture that ensures the real-time and dynamic requirements of synchronization among distributed emergency best practice models are met in a reliable and safe manner. Taking the signs, symptoms, and progress of stroke patients transported across a geographically distributed healthcare network as the motivating use case, we implement our communication system and apply it to our developed best practice automata using laboratory simulations. Our proof-of-concept experiments shows there is potential for the use of our system in a wide variety of domains.
Caruthers, Elena J; Thompson, Julie A; Chaudhari, Ajit M W; Schmitt, Laura C; Best, Thomas M; Saul, Katherine R; Siston, Robert A
2016-10-01
Sit-to-stand transfer is a common task that is challenging for older adults and others with musculoskeletal impairments. Associated joint torques and muscle activations have been analyzed two-dimensionally, neglecting possible three-dimensional (3D) compensatory movements in those who struggle with sit-to-stand transfer. Furthermore, how muscles accelerate an individual up and off the chair remains unclear; such knowledge could inform rehabilitation strategies. We examined muscle forces, muscleinduced accelerations, and interlimb muscle force differences during sit-to-stand transfer in young, healthy adults. Dynamic simulations were created using a custom 3D musculoskeletal model; static optimization and induced acceleration analysis were used to determine muscle forces and their induced accelerations, respectively. The gluteus maximus generated the largest force (2009.07 ± 277.31 N) and was a main contributor to forward acceleration of the center of mass (COM) (0.62 ± 0.18 m/s(2)), while the quadriceps opposed it. The soleus was a main contributor to upward (2.56 ± 0.74 m/s(2)) and forward acceleration of the COM (0.62 ± 0.33 m/s(2)). Interlimb muscle force differences were observed, demonstrating lower limb symmetry cannot be assumed during this task, even in healthy adults. These findings establish a baseline from which deficits and compensatory strategies in relevant populations (eg, elderly, osteoarthritis) can be identified.
NASA Astrophysics Data System (ADS)
Dalmasse, K.; Pariat, É.; Valori, G.; Jing, J.; Démoulin, P.
2018-01-01
In the solar corona, magnetic helicity slowly and continuously accumulates in response to plasma flows tangential to the photosphere and magnetic flux emergence through it. Analyzing this transfer of magnetic helicity is key for identifying its role in the dynamics of active regions (ARs). The connectivity-based helicity flux density method was recently developed for studying the 2D and 3D transfer of magnetic helicity in ARs. The method takes into account the 3D nature of magnetic helicity by explicitly using knowledge of the magnetic field connectivity, which allows it to faithfully track the photospheric flux of magnetic helicity. Because the magnetic field is not measured in the solar corona, modeled 3D solutions obtained from force-free magnetic field extrapolations must be used to derive the magnetic connectivity. Different extrapolation methods can lead to markedly different 3D magnetic field connectivities, thus questioning the reliability of the connectivity-based approach in observational applications. We address these concerns by applying this method to the isolated and internally complex AR 11158 with different magnetic field extrapolation models. We show that the connectivity-based calculations are robust to different extrapolation methods, in particular with regard to identifying regions of opposite magnetic helicity flux. We conclude that the connectivity-based approach can be reliably used in observational analyses and is a promising tool for studying the transfer of magnetic helicity in ARs and relating it to their flaring activity.
Strobl, Philipp
2016-11-01
Skiing underwent substantial changes during the post-war years when the sport turned into a multi-billion dollar industry and a leisure activity for the masses. Despite its global nature and popularity, skiing in academic writing has not gained much recognition. This paper explores the role of knowledge transfer during the pioneering phase of post-war skiing in Australia. It describes the life of Charles William Anton, an Austrian refugee from the Anschluss who migrated to Sydney and subsequently became one of the founding fathers of Australian post-war skiing. The following pages show the multi-layered nature of skiing as a global sport by exemplifying how ideas spread from pre-war Europe to post-war Australia. The paper will also provide a case study about refugee knowledge transfer and the 'productive process of absorption, adoption or rejection of knowledge' that takes place once an idea has been introduced into a new environment.
Exploring the Media Mix during IT-Offshore Project
NASA Astrophysics Data System (ADS)
Wende, Erik; Schwabe, Gerhard; Philip, Tom
Offshore outsourced IT projects continue to gain relevance in the globalized world scenario. The temporal, geographical and cultural distances involved during the development of software between distributed team members result in communication challenges. As software development involves the coding of knowledge, the management of knowledge and its transfer remain critical for the success of the project. For effective knowledge transfer between geographically dispersed teams the ongoing selection of communication medium or the media channel mix becomes highly significant. Although there is an abundance of theory dealing with knowledge transfer and media channel selection during offshore outsourcing projects, the specific role of cultural differences in the media mix is often overlooked. As a first step to rectify this, this paper presents an explorative outsourcing case study with emphasis on the chosen media channels and the problems that arose from differences in culture. The case study is analyzed in light of several theoretical models. Finally the paper presents the idea of extending the Media Synchonicity theory with cultural factors.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1994-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical communications practices of U.S. aerospace engineers and scientists affiliated with, not necessarily belonging to, the Society of Manufacturing Engineers (SME).
ERIC Educational Resources Information Center
Hannon, Kevin
2017-01-01
Contact time with students is becoming more valuable and must be utilized efficiently. Unfortunately, many students attend anatomy lectures and labs ill-prepared, and this limits efficiency. To address this issue we have created an interactive mobile app designed to facilitate the acquisition and transfer of critical anatomical knowledge in…
ERIC Educational Resources Information Center
Choi, Hye Lim
2011-01-01
This study examined the effectiveness of the Executive Master of Business Administration (EMBA) degree program in terms of transfer of knowledge and leadership practices. Based on a review of literature related to adult learning theories, EMBA programs, the importance of evaluation practices, and leadership practices, this study was designed to…
ERIC Educational Resources Information Center
Melo, Mário; Miranda, Guilhermina Lobato
2015-01-01
This study was designed to investigate the effects of two instructional approaches (4C-ID versus conventional) on learners' knowledge-acquisition and learning transfer of the electrical circuits content in Physics. Participants were 129 9th graders from a secondary school in Lisbon, M = 14.3 years, SD = 0.54. The participants were divided in two…
ERIC Educational Resources Information Center
Yates, Dan; Ward, Chris
2011-01-01
Many states are now requiring high school students to be competent in the areas of economic and financial literacy. This is due to the recent escalation of bankruptcies, large credit card debt, and mortgage foreclosures in our society. This study examines how financial knowledge is transferred from the high school level to the college level and…
ERIC Educational Resources Information Center
Cunningham, Thomas H.; Thorkildsen, Ron J.
Two multiple-case instructional treatments were compared to determine their relative effectiveness for helping program participants acquire, apply, and transfer complex knowledge about Assistive Technology (AT) available to help people with impaired vision. Thirty-eight college students were randomly assigned to two conditions. Both treatments…
ERIC Educational Resources Information Center
Roll, Ido; Butler, Deborah; Yee, Nikki; Welsh, Ashley; Perez, Sarah; Briseno, Adriana; Perkins, Katherine; Bonn, Doug
2018-01-01
Guiding inquiry learning has been shown to increase knowledge gains. Yet, little is known about the effect of guidance on attitudes and behaviours, its interaction with student attributes, and transfer of impact once guidance is removed. We address these gaps in the context of an interactive Physics simulation on electric circuits…
Empirical Knowledge Transfer and Collaboration with Self-Regenerative Systems
2007-06-01
SYSTEMS Raytheon Company Sponsored by Defense Advanced Research Projects Agency DARPA Order No. T120 APPROVED FOR PUBLIC RELEASE...FA8750-04-C-0286 5b. GRANT NUMBER 4. TITLE AND SUBTITLE EMPIRICAL KNOWLEDGE TRANSFER AND COLLABORATION WITH SELF-REGENERATIVE SYSTEMS 5c...Self-Regenerative Systems program to develop new technologies supporting granular scalable redundancy. The key focus of Raytheon’s effort was to
Toward equality of biodiversity knowledge through technology transfer.
Böhm, Monika; Collen, Ben
2015-10-01
To help stem the continuing decline of biodiversity, effective transfer of technology from resource-rich to biodiversity-rich countries is required. Biodiversity technology as defined by the Convention on Biological Diversity (CBD) is a complex term, encompassing a wide variety of activities and interest groups. As yet, there is no robust framework by which to monitor the extent to which technology transfer might benefit biodiversity. We devised a definition of biodiversity technology and a framework for the monitoring of technology transfer between CBD signatories. Biodiversity technology within the scope of the CBD encompasses hard and soft technologies that are relevant to the conservation and sustainable use of biodiversity, or make use of genetic resources, and that relate to all aspects of the CBD, with a particular focus on technology transfer from resource-rich to biodiversity-rich countries. Our proposed framework introduces technology transfer as a response indicator: technology transfer is increased to stem pressures on biodiversity. We suggest an initial approach of tracking technology flow between countries; charting this flow is likely to be a one-to-many relationship (i.e., the flow of a specific technology from one country to multiple countries). Future developments should then focus on integrating biodiversity technology transfer into the current pressure-state-response indicator framework favored by the CBD (i.e., measuring the influence of technology transfer on changes in state and pressure variables). Structured national reporting is important to obtaining metrics relevant to technology and knowledge transfer. Interim measures, that can be used to assess biodiversity technology or knowledge status while more in-depth indicators are being developed, include the number of species inventories, threatened species lists, or national red lists; databases on publications and project funding may provide measures of international cooperation. Such a pragmatic approach, followed by rigorous testing of specific technology transfer metrics submitted by CBD signatories in a standardized manner may in turn improve the focus of future targets on technology transfer for biodiversity conservation. © 2015 Society for Conservation Biology.
Contexts, concepts and cognition: principles for the transfer of basic science knowledge.
Kulasegaram, Kulamakan M; Chaudhary, Zarah; Woods, Nicole; Dore, Kelly; Neville, Alan; Norman, Geoffrey
2017-02-01
Transfer of basic science aids novices in the development of clinical reasoning. The literature suggests that although transfer is often difficult for novices, it can be optimised by two complementary strategies: (i) focusing learners on conceptual knowledge of basic science or (ii) exposing learners to multiple contexts in which the basic science concepts may apply. The relative efficacy of each strategy as well as the mechanisms that facilitate transfer are unknown. In two sequential experiments, we compared both strategies and explored mechanistic changes in how learners address new transfer problems. Experiment 1 was a 2 × 3 design in which participants were randomised to learn three physiology concepts with or without emphasis on the conceptual structure of basic science via illustrative analogies and by means of one, two or three contexts during practice (operationalised as organ systems). Transfer of these concepts to explain pathologies in familiar organ systems (near transfer) and unfamiliar organ systems (far transfer) was evaluated during immediate and delayed testing. Experiment 2 examined whether exposure to conceptual analogies and multiple contexts changed how learners classified new problems. Experiment 1 showed that increasing context variation significantly improved far transfer performance but there was no difference between two and three contexts during practice. Similarly, the increased conceptual analogies led to higher performance for far transfer. Both interventions had independent but additive effects on overall performance. Experiment 2 showed that such analogies and context variation caused learners to shift to using structural characteristics to classify new problems even when there was superficial similarity to previous examples. Understanding problems based on conceptual structural characteristics is necessary for successful transfer. Transfer of basic science can be optimised by using multiple strategies that collectively emphasise conceptual structure. This means teaching must focus on conserved basic science knowledge and de-emphasise superficial features. © 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education.
A Structural Model for a Self-Assembled Nanotube Provides Insight into Its Exciton Dynamics
2016-01-01
The design and synthesis of functional self-assembled nanostructures is frequently an empirical process fraught with critical knowledge gaps about atomic-level structure in these noncovalent systems. Here, we report a structural model for a semiconductor nanotube formed via the self-assembly of naphthalenediimide-lysine (NDI-Lys) building blocks determined using experimental 13C–13C and 13C–15N distance restraints from solid-state nuclear magnetic resonance supplemented by electron microscopy and X-ray powder diffraction data. The structural model reveals a two-dimensional-crystal-like architecture of stacked monolayer rings each containing ∼50 NDI-Lys molecules, with significant π-stacking interactions occurring both within the confines of the ring and along the long axis of the tube. Excited-state delocalization and energy transfer are simulated for the nanotube based on time-dependent density functional theory and an incoherent hopping model. Remarkably, these calculations reveal efficient energy migration from the excitonic bright state, which is in agreement with the rapid energy transfer within NDI-Lys nanotubes observed previously using fluorescence spectroscopy. PMID:26120375
Parental Support and Youth Occupational Attainment: Help or Hindrance?
Manzoni, Anna
2018-05-02
Although several concerns surround the transition to adulthood and youth increasingly rely on parental support, our knowledge about the implications of parental support for youth development and transition to adulthood is limited. This study fills this gap by conceptualizing development within a life course perspective that links social inequality and early life course transitions. It draws on a subsample of youth observed between age 18 and 28 from the Transition to Adulthood supplement of the Panel Study of Income Dynamics 2005-2015 (N = 7,542; 53% female, 51.3% white). Mixed-effects models reveal that the more direct financial transfers youth receive, the higher their occupational status. Yet, indirect financial support parents offer through co-residence shows the opposite pattern. Among youth receiving monetary transfers, college graduates have particularly high occupational status; however, among youth living with their parents, college graduates have the lowest occupational status. Although different types of parental support may equally act as safety nets, their divergent implications for youths' occupational attainment raise concerns about the reproduction and possible intensification of inequality during this developmental stage.
Stöckel, Tino; Wang, Jinsung
2011-11-01
Interlimb transfer of motor learning, indicating an improvement in performance with one limb following training with the other, often occurs asymmetrically (i.e., from non-dominant to dominant limb or vice versa, but not both). In the present study, we examined whether interlimb transfer of the same motor task could occur asymmetrically and in opposite directions (i.e., from right to left leg vs. left to right leg) depending on individuals' conception of the task. Two experimental conditions were tested: In a dynamic control condition, the process of learning was facilitated by providing the subjects with a type of information that forced them to focus on dynamic features of a given task (force impulse); and in a spatial control condition, it was done with another type of information that forced them to focus on visuomotor features of the same task (distance). Both conditions employed the same leg extension task. In addition, a fully-crossed transfer paradigm was used in which one group of subjects initially practiced with the right leg and were tested with the left leg for a transfer test, while the other group used the two legs in the opposite order. The results showed that the direction of interlimb transfer varied depending on the condition, such that the right and the left leg benefited from initial training with the opposite leg only in the spatial and the dynamic condition, respectively. Our finding suggests that manipulating the conception of a leg extension task has a substantial influence on the pattern of interlimb transfer in such a way that the direction of transfer can even be opposite depending on whether the task is conceived as a dynamic or spatial control task. Copyright © 2011 Elsevier Inc. All rights reserved.
Assessing the Dynamic Behavior of Online Q&A Knowledge Markets: A System Dynamics Approach
ERIC Educational Resources Information Center
Jafari, Mostafa; Hesamamiri, Roozbeh; Sadjadi, Jafar; Bourouni, Atieh
2012-01-01
Purpose: The objective of this paper is to propose a holistic dynamic model for understanding the behavior of a complex and internet-based kind of knowledge market by considering both social and economic interactions. Design/methodology/approach: A system dynamics (SD) model is formulated in this study to investigate the dynamic characteristics of…
Cognitive algorithms: dynamic logic, working of the mind, evolution of consciousness and cultures
NASA Astrophysics Data System (ADS)
Perlovsky, Leonid I.
2007-04-01
The paper discusses evolution of consciousness driven by the knowledge instinct, a fundamental mechanism of the mind which determines its higher cognitive functions. Dynamic logic mathematically describes the knowledge instinct. It overcomes past mathematical difficulties encountered in modeling intelligence and relates it to mechanisms of concepts, emotions, instincts, consciousness and unconscious. The two main aspects of the knowledge instinct are differentiation and synthesis. Differentiation is driven by dynamic logic and proceeds from vague and unconscious states to more crisp and conscious states, from less knowledge to more knowledge at each hierarchical level of the mind. Synthesis is driven by dynamic logic operating in a hierarchical organization of the mind; it strives to achieve unity and meaning of knowledge: every concept finds its deeper and more general meaning at a higher level. These mechanisms are in complex relationship of symbiosis and opposition, which leads to complex dynamics of evolution of consciousness and cultures. Modeling this dynamics in a population leads to predictions for the evolution of consciousness, and cultures. Cultural predictive models can be compared to experimental data and used for improvement of human conditions. We discuss existing evidence and future research directions.
Knowledge structures and the acquisition of a complex skill.
Day, E A; Arthur, W; Gettman, D
2001-10-01
The purpose of this study was to examine the viability of knowledge structures as an operationalization of learning in the context of a task that required a high degree of skill. Over the course of 3 days, 86 men participated in 9 training sessions and learned a complex video game. At the end of acquisition, participants' knowledge structures were assessed. After a 4-day nonpractice interval, trainees completed tests of skill retention and skill transfer. Findings indicated that the similarity of trainees' knowledge structures to an expert structure was correlated with skill acquisition and was predictive of skill retention and skill transfer. However, the magnitude of these effects was dependent on the method used to derive the expert referent structure. Moreover, knowledge structures mediated the relationship between general cognitive ability and skill-based performance.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Kennedy, John M.
1990-01-01
The objective of the NASA/DOD Aerospace Knowledge Diffusion Research Project is to provide descriptive and analytical data regarding the flow of scientific and technical information (STI) at the individual, organizational, national, and international levels, placing emphasis on the systems used to diffuse the results of federally funded aerospace STI. An overview of project assumptions, objectives, and design is presented and preliminary results of the phase 2 aerospace library survey are summarized. Phase 2 addressed aerospace knowledge transfer and use within the larger social system and focused on the flow of aerospace STI in government and industry and the role of the information intermediary in knowledge transfer.
Eby, Lillian T.; Curtis, Sara L.
2014-01-01
This longitudinal study investigated the extent to which substance abuse (SA) clinician turnover is associated with SA-specific knowledge loss due to change in professions (professional turnover) versus SA-specific knowledge transfer due to movement from one SA clinical setting to another (treatment program turnover). For this study, clinicians had to voluntarily leave their current treatment program. Eligible clinicians completed a quantitative survey while employed and a qualitative post-employment exit interview 1 year later. Compared to those that exited the SA profession (N = 99), clinicians who changed treatment programs (N = 120) had greater SA-specific formal knowledge and were more likely to be personally in recovery. No differences were found between the two groups in terms of SA-specific practical knowledge. PMID:25115318
The Case for Case-Based Transfer Learning
2011-01-01
Thorndike and Woodworth 1901; Perkins and Salomon 1994; Bransford, Brown, and Cocking 2000), among other disciplines. Transfer learning uses knowledge...Transfer Learning for Rein- forcement Learning Domains: A Survey. Journal of Machine Learning Research 10(1): 1633–1685. Thorndike , E. L., and
NASA Astrophysics Data System (ADS)
Aziz, Jonathan D.; Parker, Jeffrey S.; Scheeres, Daniel J.; Englander, Jacob A.
2018-01-01
Low-thrust trajectories about planetary bodies characteristically span a high count of orbital revolutions. Directing the thrust vector over many revolutions presents a challenging optimization problem for any conventional strategy. This paper demonstrates the tractability of low-thrust trajectory optimization about planetary bodies by applying a Sundman transformation to change the independent variable of the spacecraft equations of motion to an orbit angle and performing the optimization with differential dynamic programming. Fuel-optimal geocentric transfers are computed with the transfer duration extended up to 2000 revolutions. The flexibility of the approach to higher fidelity dynamics is shown with Earth's J 2 perturbation and lunar gravity included for a 500 revolution transfer.
NASA Astrophysics Data System (ADS)
Aziz, Jonathan D.; Parker, Jeffrey S.; Scheeres, Daniel J.; Englander, Jacob A.
2018-06-01
Low-thrust trajectories about planetary bodies characteristically span a high count of orbital revolutions. Directing the thrust vector over many revolutions presents a challenging optimization problem for any conventional strategy. This paper demonstrates the tractability of low-thrust trajectory optimization about planetary bodies by applying a Sundman transformation to change the independent variable of the spacecraft equations of motion to an orbit angle and performing the optimization with differential dynamic programming. Fuel-optimal geocentric transfers are computed with the transfer duration extended up to 2000 revolutions. The flexibility of the approach to higher fidelity dynamics is shown with Earth's J 2 perturbation and lunar gravity included for a 500 revolution transfer.
Dai, Chien-Yun; Chen, Hsiao-Ming; Chen, Wan-Fei; Wu, Chia-Huei; Li, Guodong; Wang, Jiangtao
2017-01-01
The purpose of this study was to explore the relationships among employees' usage intention pertaining to mobile information devices, focusing on subjective judgement, technology acceptance tendency, information sharing behavior and information transfer. A research model was established to verify several hypotheses. The research model based on integrated concepts of knowledge management and technology acceptance modeling. Participants were employees of enterprises in Taiwan, selected by combining snowball and convenience sampling. Data obtained from 779 e-surveys. Multiple-regression analysis was employed for hypothesis verification. The results indicate that perceived ease-of-use of mobile devices was affected by computer self-efficacy and computer playfulness directly; meanwhile, perceived ease-of-use directly affects perceived usefulness. In addition, perceived ease-of-use and perceived usefulness can predict information-sharing behavior in a positive manner, and impact knowledge transfer as well. Based on the research findings, it suggested that enterprises should utilize mobile information devices to create more contact with customers and enrich their service network. In addition, it is recommended that managers use mobile devices to transmit key information to their staff and that they use these devices for problem-solving and decision-making. Further, the staff’s skills pertaining to the operation of mobile information devices and to fully implement their features are reinforced in order to inspire the users' knowledge transfer. Enhancing the playfulness of the interface is also important. In general, it is useful to promote knowledge transfer behavior within an organization by motivating members to share information and ideas via mobile information devices. In addition, a well-designed interface can facilitate employees' use of these devices. PMID:28886088
Yuan, Yu-Hsi; Tsai, Sang-Bing; Dai, Chien-Yun; Chen, Hsiao-Ming; Chen, Wan-Fei; Wu, Chia-Huei; Li, Guodong; Wang, Jiangtao
2017-01-01
The purpose of this study was to explore the relationships among employees' usage intention pertaining to mobile information devices, focusing on subjective judgement, technology acceptance tendency, information sharing behavior and information transfer. A research model was established to verify several hypotheses. The research model based on integrated concepts of knowledge management and technology acceptance modeling. Participants were employees of enterprises in Taiwan, selected by combining snowball and convenience sampling. Data obtained from 779 e-surveys. Multiple-regression analysis was employed for hypothesis verification. The results indicate that perceived ease-of-use of mobile devices was affected by computer self-efficacy and computer playfulness directly; meanwhile, perceived ease-of-use directly affects perceived usefulness. In addition, perceived ease-of-use and perceived usefulness can predict information-sharing behavior in a positive manner, and impact knowledge transfer as well. Based on the research findings, it suggested that enterprises should utilize mobile information devices to create more contact with customers and enrich their service network. In addition, it is recommended that managers use mobile devices to transmit key information to their staff and that they use these devices for problem-solving and decision-making. Further, the staff's skills pertaining to the operation of mobile information devices and to fully implement their features are reinforced in order to inspire the users' knowledge transfer. Enhancing the playfulness of the interface is also important. In general, it is useful to promote knowledge transfer behavior within an organization by motivating members to share information and ideas via mobile information devices. In addition, a well-designed interface can facilitate employees' use of these devices.
Efficient dynamic coherence transfer relying on offset locking using optical phase-locked loop
NASA Astrophysics Data System (ADS)
Xie, Weilin; Dong, Yi; Bretenaker, Fabien; Shi, Hongxiao; Zhou, Qian; Xia, Zongyang; Qin, Jie; Zhang, Lin; Lin, Xi; Hu, Weisheng
2018-01-01
We design and experimentally demonstrate a highly efficient coherence transfer based on composite optical phaselocked loop comprising multiple feedback servo loops. The heterodyne offset-locking is achieved by conducting an acousto-optic frequency shifter in combination with the current tuning and the temperature controlling of the semiconductor laser. The adaptation of the composite optical phase-locked loop enables the tight coherence transfer from a frequency comb to a semiconductor laser in a fully dynamic manner.
The dynamics of meaningful social interactions and the emergence of collective knowledge
Dankulov, Marija Mitrović; Melnik, Roderick; Tadić, Bosiljka
2015-01-01
Collective knowledge as a social value may arise in cooperation among actors whose individual expertise is limited. The process of knowledge creation requires meaningful, logically coordinated interactions, which represents a challenging problem to physics and social dynamics modeling. By combining two-scale dynamics model with empirical data analysis from a well-known Questions & Answers system Mathematics, we show that this process occurs as a collective phenomenon in an enlarged network (of actors and their artifacts) where the cognitive recognition interactions are properly encoded. The emergent behavior is quantified by the information divergence and innovation advancing of knowledge over time and the signatures of self-organization and knowledge sharing communities. These measures elucidate the impact of each cognitive element and the individual actor’s expertise in the collective dynamics. The results are relevant to stochastic processes involving smart components and to collaborative social endeavors, for instance, crowdsourcing scientific knowledge production with online games. PMID:26174482
The dynamics of meaningful social interactions and the emergence of collective knowledge
NASA Astrophysics Data System (ADS)
Dankulov, Marija Mitrović; Melnik, Roderick; Tadić, Bosiljka
2015-07-01
Collective knowledge as a social value may arise in cooperation among actors whose individual expertise is limited. The process of knowledge creation requires meaningful, logically coordinated interactions, which represents a challenging problem to physics and social dynamics modeling. By combining two-scale dynamics model with empirical data analysis from a well-known Questions & Answers system Mathematics, we show that this process occurs as a collective phenomenon in an enlarged network (of actors and their artifacts) where the cognitive recognition interactions are properly encoded. The emergent behavior is quantified by the information divergence and innovation advancing of knowledge over time and the signatures of self-organization and knowledge sharing communities. These measures elucidate the impact of each cognitive element and the individual actor’s expertise in the collective dynamics. The results are relevant to stochastic processes involving smart components and to collaborative social endeavors, for instance, crowdsourcing scientific knowledge production with online games.
The dynamics of meaningful social interactions and the emergence of collective knowledge.
Dankulov, Marija Mitrović; Melnik, Roderick; Tadić, Bosiljka
2015-07-15
Collective knowledge as a social value may arise in cooperation among actors whose individual expertise is limited. The process of knowledge creation requires meaningful, logically coordinated interactions, which represents a challenging problem to physics and social dynamics modeling. By combining two-scale dynamics model with empirical data analysis from a well-known Questions &Answers system Mathematics, we show that this process occurs as a collective phenomenon in an enlarged network (of actors and their artifacts) where the cognitive recognition interactions are properly encoded. The emergent behavior is quantified by the information divergence and innovation advancing of knowledge over time and the signatures of self-organization and knowledge sharing communities. These measures elucidate the impact of each cognitive element and the individual actor's expertise in the collective dynamics. The results are relevant to stochastic processes involving smart components and to collaborative social endeavors, for instance, crowdsourcing scientific knowledge production with online games.
Toogood, Helen S; Leys, David; Scrutton, Nigel S
2007-11-01
Electron transferring flavoproteins (ETFs) are soluble heterodimeric FAD-containing proteins that function primarily as soluble electron carriers between various flavoprotein dehydrogenases. ETF is positioned at a key metabolic branch point, responsible for transferring electrons from up to 10 primary dehydrogenases to the membrane-bound respiratory chain. Clinical mutations of ETF result in the often fatal disease glutaric aciduria type II. Structural and biophysical studies of ETF in complex with partner proteins have shown that ETF partitions the functions of partner binding and electron transfer between (a) a 'recognition loop', which acts as a static anchor at the ETF-partner interface, and (b) a highly mobile redox-active FAD domain. Together, this enables the FAD domain of ETF to sample a range of conformations, some compatible with fast interprotein electron transfer. This 'conformational sampling' enables ETF to recognize structurally distinct partners, whilst also maintaining a degree of specificity. Complex formation triggers mobility of the FAD domain, an 'induced disorder' mechanism contrasting with the more generally accepted models of protein-protein interaction by induced fit mechanisms. We discuss the implications of the highly dynamic nature of ETFs in biological interprotein electron transfer. ETF complexes point to mechanisms of electron transfer in which 'dynamics drive function', a feature that is probably widespread in biology given the modular assembly and flexible nature of biological electron transfer systems.
Høglend, Per; Amlo, Svein; Marble, Alice; Bøgwald, Kjell-Petter; Sørbye, Oystein; Sjaastad, Mary Cosgrove; Heyerdahl, Oscar
2006-10-01
The purpose of this study was to measure the effects of transference interpretations (the assumed core active ingredient) in dynamic psychotherapy, using an experimental design. One hundred patients were randomly assigned to two groups. One group received dynamic psychotherapy over 1 year, with a moderate level of transference interpretations, while the other group received dynamic psychotherapy with no transference interpretations. The most common axis I disorders were depression and anxiety disorders. Forty-six patients fulfilled the general criteria for personality disorder. Seven experienced psychotherapists treated patients in both groups. Five full sessions from each treatment were rated by two evaluators with process measures in order to document treatment integrity. Outcome variables were the Psychodynamic Functioning Scales, Inventory of Interpersonal Problems Scale-Circumplex version, Global Assessment of Functioning Scale, and Symptom Checklist-90-R. Quality of Object Relations Scale (lifelong pattern) and personality disorders were preselected as possible moderators of treatment effects. Change was assessed using linear-mixed models. Clinically significant change was also calculated. The authors could not demonstrate differential treatment effects between the groups. However, the moderator analyses showed that transference interpretations were more helpful for patients with a lifelong history of less mature object relations. Small negative effects were observed for patients with mature object relations. The authors could not show differences in average effectiveness between treatments. However, the moderator analyses indicated that treatment worked through different active ingredients for different patients. Contrary to common expectation, patients with poor object relations profited more from therapy with transference interpretations than from therapy with no transference interpretations.
Lei, Dongsheng; Rames, Matthew; Zhang, Xing; ...
2016-05-03
Cholesteryl ester transfer protein (CETP) mediates cholesteryl ester (CE) transfer from the atheroprotective high density lipoprotein (HDL) cholesterol to the atherogenic low density lipoprotein cholesterol. In the past decade, this property has driven the development of CETP inhibitors, which have been evaluated in large scale clinical trials for treating cardiovascular diseases. Despite the pharmacological interest, little is known about the fundamental mechanism of CETP in CE transfer. Recent electron microscopy (EM) experiments have suggested a tunnel mechanism, and molecular dynamics simulations have shown that the flexible N-terminal distal end of CETP penetrates into the HDL surface and takes up amore » CE molecule through an open pore. However, it is not known whether a CE molecule can completely transfer through an entire CETP molecule. Here, we used all-atom molecular dynamics simulations to evaluate this possibility. The results showed that a hydrophobic tunnel inside CETP is sufficient to allow a CE molecule to completely transfer through the entire CETP within a predicted transfer time and at a rate comparable with those obtained through physiological measurements. Analyses of the detailed interactions revealed several residues that might be critical for CETP function, which may provide important clues for the effective development of CETP inhibitors and treatment of cardiovascular diseases.« less
ERIC Educational Resources Information Center
Gonzalez, John A.
2012-01-01
A critical goal of many school and training interventions is to provide learners with the strategies and foundational knowledge that will allow them to tackle novel problems encountered under circumstances different than the learning situations. This is also quite often referred to as the ability to transfer learning. Theories of transfer posit…
ERIC Educational Resources Information Center
Baer, Tom
2013-01-01
Transfer of learning from curricular experiences to non-academic settings is a primary goal of any academic institution. In cases where skills, knowledge, and attitudes learned in curricular experiences are used to solve complex problems, transfer is especially difficult to define and measure. This study attempts to better define transfer in…
Lauritzen, Camilla; Reedtz, Charlotte
2015-01-01
Mental health problems are often transmitted from one generation to the next. However, transferring knowledge about interventions that reduce intergenerational transmission of disease to the field of parental mental illness has been very difficult. One of the most critical issues in mental health services research is the gap between what is generally known about effective treatment and what is provided to consumers in routine care. In this article we discuss several aspects of knowledge transfer in the field of parental mental illness. Effective strategies and implementation prerequisites are explored, and we also discuss indicators of success and sustainability. Altogether, this article presents a rationale for the importance of preventive strategies for children of mentally ill parents. Furthermore, the discussion shows how complex it is to change clinical practice.
Ab initio treatment of ion-induced charge transfer dynamics of isolated 2-deoxy-D-ribose.
Bacchus-Montabonel, Marie-Christine
2014-08-21
Modeling-induced radiation damage in biological systems, in particular, in DNA building blocks, is of major concern in cancer therapy studies. Ion-induced charge-transfer dynamics may indeed be involved in proton and hadrontherapy treatments. We have thus performed a theoretical approach of the charge-transfer dynamics in collision of C(4+) ions and protons with isolated 2-deoxy-D-ribose in a wide collision energy range by means of ab initio quantum chemistry molecular methods. The comparison of both projectile ions has been performed with regard to previous theoretical and experimental results. The charge transfer appears markedly less efficient with the 2-deoxy-D-ribose target than that with pyrimidine nucleobases, which would induce an enhancement of the fragmentation process in agreement with experimental measurements. The mechanism has been analyzed with regard to inner orbital excitations, and qualitative tendencies have been pointed out for studies on DNA buiding block damage.
PRESTO polarization transfer to quadrupolar nuclei: Implications for dynamic nuclear polarization
Perras, Frederic A.; Kobayashi, Takeshi; Pruski, Marek
2015-08-04
In this study, we show both experimentally and numerically on a series of model systems that in experiments involving transfer of magnetization from 1H to the quadrupolar nuclei under magic-angle-spinning (MAS), the PRESTO technique consistently outperforms traditionally used cross polarization (CP), affording more quantitative intensities, improved lineshapes, better overall sensitivity, and straightforward optimization. This advantage derives from the fact that PRESTO circumvents the convoluted and uncooperative spin dynamics during the CP transfer under MAS, by replacing the spin-locking of quadrupolar nuclei with a single central transition selective 90° pulse and using a symmetry-based recoupling sequence in the 1H channel. Thismore » is important in the context of dynamic nuclear polarization (DNP) NMR of quadrupolar nuclei, where the efficient transfer of enhanced 1H polarization is desired to obtain the highest sensitivity.« less
NASA Astrophysics Data System (ADS)
Nibbering, Erik T. J.; Fidder, Henk; Pines, Ehud
2005-05-01
Time-resolved infrared (IR) and Raman spectroscopy elucidates molecular structure evolution during ultrafast chemical reactions. Following vibrational marker modes in real time provides direct insight into the structural dynamics, as is evidenced in studies on intramolecular hydrogen transfer, bimolecular proton transfer, electron transfer, hydrogen bonding during solvation dynamics, bond fission in organometallic compounds and heme proteins, cis-trans isomerization in retinal proteins, and transformations in photochromic switch pairs. Femtosecond IR spectroscopy monitors the site-specific interactions in hydrogen bonds. Conversion between excited electronic states can be followed for intramolecular electron transfer by inspection of the fingerprint IR- or Raman-active vibrations in conjunction with quantum chemical calculations. Excess internal vibrational energy, generated either by optical excitation or by internal conversion from the electronic excited state to the ground state, is observable through transient frequency shifts of IR-active vibrations and through nonequilibrium populations as deduced by Raman resonances.
The Fountain of Health: Bringing Seniors’ Mental Health Promotion into Clinical Practice
Thoo, Vanessa; Freer, Janya; Cassidy, Keri-Leigh
2015-01-01
Background The Fountain of Health (FoH) initiative offers valuable evidence-based mental health knowledge and provides clinicians with evaluated tools for translating knowledge into practice, in order to reduce seniors’ risks of mental disorders, including dementia. Methods A presentation on mental health promotion and educational materials were disseminated to mental health clinicians including physicians and other allied health professionals either in-person or via tele-education through a provincial seniors’ mental health network. Measures included: 1) a tele-education quality evaluation form, 2) a knowledge transfer questionnaire, 3) a knowledge translation-to-practice evaluation tool, and 4) a quality assurance questionnaire. Results A total of 74 mental health clinicians received the FoH education session. There was a highly significant (p < .0001) difference in clinicians’ knowledge transfer questionnaire scores pre- and post-educational session. At a two-month follow-up, 19 (25.7%) participants completed a quality assurance questionnaire, with all 19 (100%) of respondents stating they would positively recommend the FoH information to colleagues and patients. Eleven (20.4%) translation-to-practice forms were also collected at this interval, tracking clinician use of the educational materials. Conclusions The use of a formalized network for knowledge transfer allows for education and evaluation of health-care practitioners in both acquisition of practical knowledge and subsequent clinical behavior change. PMID:26740830
Chemical Kinetics, Heat Transfer, and Sensor Dynamics Revisited in a Simple Experiment
ERIC Educational Resources Information Center
Sad, Maria E.; Sad, Mario R.; Castro, Alberto A.; Garetto, Teresita F.
2008-01-01
A simple experiment about thermal effects in chemical reactors is described, which can be used to illustrate chemical reactor models, the determination and validation of their parameters, and some simple principles of heat transfer and sensor dynamics. It is based in the exothermic reaction between aqueous solutions of sodium thiosulfate and…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-06
... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 5379-008] New Hampshire Water Resources Board, Hydro Dynamics Corporation; Notice of Transfer of Exemption 1. By letter filed April 16, 2013, New Hampshire Water Resources Board co-exemptee and the New Hampshire Department of...
NASA Astrophysics Data System (ADS)
Xu, Jiuping; Ma, Ning; Lv, Chengwei
2016-08-01
Efficient water transfer and allocation are critical for disaster mitigation in drought emergencies. This is especially important when the different interests of the multiple decision makers and the fluctuating water resource supply and demand simultaneously cause space and time conflicts. To achieve more effective and efficient water transfers and allocations, this paper proposes a novel optimization method with an integrated bi-level structure and a dynamic strategy, in which the bi-level structure works to deal with space dimension conflicts in drought emergencies, and the dynamic strategy is used to deal with time dimension conflicts. Combining these two optimization methods, however, makes calculation complex, so an integrated interactive fuzzy program and a PSO-POA are combined to develop a hybrid-heuristic algorithm. The successful application of the proposed model in a real world case region demonstrates its practicality and efficiency. Dynamic cooperation between multiple reservoirs under the coordination of a global regulator reflects the model's efficiency and effectiveness in drought emergency water transfer and allocation, especially in a fluctuating environment. On this basis, some corresponding management recommendations are proposed to improve practical operations.
NASA Technical Reports Server (NTRS)
Mckillop, A. A.; Baughn, J. W.; Dwyer, H. A.
1976-01-01
Major research advances in heat transfer and fluid dynamics are outlined, with particular reference to relevant energy problems. Of significant importance are such topics as synthetic fuels in combustion, turbulence models, combustion modeling, numerical methods for interacting boundary layers, and light-scattering diagnostics for gases. The discussion covers thermal convection, two-phase flow and boiling heat transfer, turbulent flows, combustion, and aerospace heat transfer problems. Other areas discussed include compressible flows, fluid mechanics and drag, and heat exchangers. Featured topics comprise heat and salt transfer in double-diffusive systems, limits of boiling heat transfer in a liquid-filled enclosure, investigation of buoyancy-induced flow stratification in a cylindrical plenum, and digital algorithms for dynamic analysis of a heat exchanger. Individual items are announced in this issue.
NASA Astrophysics Data System (ADS)
Lengyel, Jozef; Med, Jakub; Slavíček, Petr; Beyer, Martin K.
2017-09-01
The reaction of HNO3 with hydrated electrons (H2O)n- (n = 35-65) in the gas phase was studied using Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry and ab initio molecular dynamics simulations. Kinetic analysis of the experimental data shows that OH-(H2O)m is formed primarily via a reaction of the hydrated electron with HNO3 inside the cluster, while proton transfer is not observed and NO3-(H2O)m is just a secondary product. The reaction enthalpy was determined using nanocalorimetry, revealing a quite exothermic charge transfer with -241 ± 69 kJ mol-1. Ab initio molecular dynamics simulations indicate that proton transfer is an allowed reaction pathway, but the overall thermochemistry favors charge transfer.
Knowledge Theories Can Inform Evaluation Practice: What Can a Complexity Lens Add?
ERIC Educational Resources Information Center
Hawe, Penelope; Bond, Lyndal; Butler, Helen
2009-01-01
Programs and policies invariably contain new knowledge. Theories about knowledge utilization, diffusion, implementation, transfer, and knowledge translation theories illuminate some mechanisms of change processes. But more often than not, when it comes to understanding patterns about change processes, "the foreground" is privileged more…
Building customer capital through knowledge management processes in the health care context.
Liu, Sandra S; Lin, Carol Yuh-Yun
2007-01-01
Customer capital is a value generated and an asset developed from customer relationships. Successfully managing these relationships is enhanced by knowledge management (KM) infrastructure that captures and transfers customer-related knowledge. The execution of such a system relies on the vision and determination of the top management team (TMT). The health care industry in today's knowledge economy encounters similar challenges of consumerism as its business sector. Developing customer capital is critical for hospitals to remain competitive in the market. This study aims to provide taxonomy for cultivating market-based organizational learning that leads to building of customer capital and attaining desirable financial performance in health care. With the advancement of technology, the KM system plays an important moderating role in the entire process. The customer capital issue has not been fully explored either in the business or the health care industry. The exploratory nature of such a pursuit calls for a qualitative approach. This study examines the proposed taxonomy with the case hospital. The lessons learned also are reflected with three US-based health networks. The TMT incorporated the knowledge process of conceptualization and transformation in their organizational mission. The market-oriented learning approach promoted by TMT helps with the accumulation and sharing of knowledge that prepares the hospital for the dynamics in the marketplace. Their key knowledge advancement relies on both the professional arena and the feedback of customers. The institutionalization of the KM system and organizational culture expands the hospital's customer capital. The implication is twofold: (1) the TMT is imperative for the success of building customer capital through KM process; and (2) the team effort should be enhanced with a learning culture and sharing spirit, in particular, active nurse participation in decision making and frontline staff's role in providing a delightfully surprising patient experience.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Bishop, Ann P.; Barclay, Rebecca O.; Kennedy, John M.
1992-01-01
Increasing reliance on and investment in information technology and electronic networking systems presupposes that computing and information technology will play a major role in the diffusion of aerospace knowledge. Little is known, however, about actual information technology needs, uses, and problems within the aerospace knowledge diffusion process. The authors state that the potential contributions of information technology to increased productivity and competitiveness will be diminished unless empirically derived knowledge regarding the information-seeking behavior of the members of the social system - those who are producing, transferring, and using scientific and technical information - is incorporated into a new technology policy framework. Research into the use of information technology and electronic networks by U.S. aerospace engineers and scientists, collected as part of a research project designed to study aerospace knowledge diffusion, is presented in support of this assertion.
Adapting Knowledge Translation Strategies for Rare Rheumatic Diseases.
Cellucci, Tania; Lee, Shirley; Webster, Fiona
2016-08-01
Rare rheumatic diseases present unique challenges to knowledge translation (KT) researchers. There is often an urgent need to transfer knowledge from research findings into clinical practice to facilitate earlier diagnosis and better outcomes. However, existing KT frameworks have not addressed the specific considerations surrounding rare diseases for which gold standard evidence is not available. Several widely adopted models provide guidance for processes and problems associated with KT. However, they do not address issues surrounding creation or synthesis of knowledge for rare diseases. Additional problems relate to lack of awareness or experience in intended knowledge users, low motivation, and potential barriers to changing practice or policy. Strategies to address the challenges of KT for rare rheumatic diseases include considering different levels of evidence available, linking knowledge creation and transfer directly, incorporating patient and physician advocacy efforts to generate awareness of conditions, and selecting strategies to address barriers to practice or policy change.
The mediating role of insight for long-term improvements in psychodynamic therapy.
Johansson, Paul; Høglend, Per; Ulberg, Randi; Amlo, Svein; Marble, Alice; Bøgwald, Kjell-Petter; Sørbye, Oystein; Sjaastad, Mary Cosgrove; Heyerdahl, Oscar
2010-06-01
According to psychoanalytic theory, interpretation of transference leads to increased insight that again leads to improved interpersonal functioning over time. In this study, we performed a full mediational analysis to test whether insight gained during treatment mediates the long-term effects of transference interpretation in dynamic psychotherapy. This study is a randomized clinical trial with a dismantling design. One hundred outpatients seeking psychotherapy for depression, anxiety, personality disorders, and interpersonal problems were randomly assigned to 1 year of weekly sessions of dynamic psychotherapy with transference interpretation or to the same type and duration of treatment with the same therapists but without the use of transference interpretation. Interpersonal functioning and insight were measured pretreatment, posttreatment, and 1 year and 3 years after treatment termination. Contrary to common expectation, patients with a life-long pattern of low quality of object relations and personality disorder pathology profited more from therapy with transference interpretation than from therapy with no transference interpretation. This long-term effect was mediated by an increase in the level of insight during treatment. Insight seems to be a key mechanism of change in dynamic psychotherapy. Our results bridge the gap between clinical theory and empirical research.
Dynamics of networks of excitatory and inhibitory neurons in response to time-dependent inputs.
Ledoux, Erwan; Brunel, Nicolas
2011-01-01
We investigate the dynamics of recurrent networks of excitatory (E) and inhibitory (I) neurons in the presence of time-dependent inputs. The dynamics is characterized by the network dynamical transfer function, i.e., how the population firing rate is modulated by sinusoidal inputs at arbitrary frequencies. Two types of networks are studied and compared: (i) a Wilson-Cowan type firing rate model; and (ii) a fully connected network of leaky integrate-and-fire (LIF) neurons, in a strong noise regime. We first characterize the region of stability of the "asynchronous state" (a state in which population activity is constant in time when external inputs are constant) in the space of parameters characterizing the connectivity of the network. We then systematically characterize the qualitative behaviors of the dynamical transfer function, as a function of the connectivity. We find that the transfer function can be either low-pass, or with a single or double resonance, depending on the connection strengths and synaptic time constants. Resonances appear when the system is close to Hopf bifurcations, that can be induced by two separate mechanisms: the I-I connectivity and the E-I connectivity. Double resonances can appear when excitatory delays are larger than inhibitory delays, due to the fact that two distinct instabilities exist with a finite gap between the corresponding frequencies. In networks of LIF neurons, changes in external inputs and external noise are shown to be able to change qualitatively the network transfer function. Firing rate models are shown to exhibit the same diversity of transfer functions as the LIF network, provided delays are present. They can also exhibit input-dependent changes of the transfer function, provided a suitable static non-linearity is incorporated.
Ishara Silva, K; Jagannathan, Bharat; Golbeck, John H; Lakshmi, K V
2016-05-01
Site-directed spin labeling electron paramagnetic resonance (SDSL EPR) spectroscopy is a powerful tool to determine solvent accessibility, side-chain dynamics, and inter-spin distances at specific sites in biological macromolecules. This information provides important insights into the structure and dynamics of both natural and designed proteins and protein complexes. Here, we discuss the application of SDSL EPR spectroscopy in probing the charge-transfer cofactors in photosynthetic reaction centers (RC) such as photosystem I (PSI) and the bacterial reaction center (bRC). Photosynthetic RCs are large multi-subunit proteins (molecular weight≥300 kDa) that perform light-driven charge transfer reactions in photosynthesis. These reactions are carried out by cofactors that are paramagnetic in one of their oxidation states. This renders the RCs unsuitable for conventional nuclear magnetic resonance spectroscopy investigations. However, the presence of native paramagnetic centers and the ability to covalently attach site-directed spin labels in RCs makes them ideally suited for the application of SDSL EPR spectroscopy. The paramagnetic centers serve as probes of conformational changes, dynamics of subunit assembly, and the relative motion of cofactors and peptide subunits. In this review, we describe novel applications of SDSL EPR spectroscopy for elucidating the effects of local structure and dynamics on the electron-transfer cofactors of photosynthetic RCs. Because SDSL EPR Spectroscopy is uniquely suited to provide dynamic information on protein motion, it is a particularly useful method in the engineering and analysis of designed electron transfer proteins and protein networks. This article is part of a Special Issue entitled Biodesign for Bioenergetics--the design and engineering of electronic transfer cofactors, proteins and protein networks, edited by Ronald L. Koder and J.L. Ross Anderson. Copyright © 2016. Published by Elsevier B.V.
ERIC Educational Resources Information Center
Rachford, Maryann Kvietkauskas
2011-01-01
The transference of learning from one discipline to another creates new knowledge between subjects. Students can connect and apply what they learn in one subject to previously existing knowledge. Art expression is an integral part of human nature and has been a means of communication throughout history. Through the integration of art with science…
ERIC Educational Resources Information Center
West, Andrew
2011-01-01
The purpose of this study was to explore and identify the experiences that informed the development of three veteran (15+ years of teaching experience) 9th grade physics teachers' specialized knowledge, or PCK, for using representations to teach the topics of energy transformation and transfer. Through the lens of phenomenography, the study…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lagos, L.; Upadhyay, H.; Shoffner, P.
2013-07-01
Deactivation and decommissioning (D and D) work is a high risk and technically challenging enterprise within the U.S. Department of Energy complex. During the past three decades, the DOE's Office of Environmental Management has been in charge of carrying out one of the largest environmental restoration efforts in the world: the cleanup of the Manhattan Project legacy. In today's corporate world, worker experiences and knowledge that have developed over time represent a valuable corporate asset. The ever-dynamic workplace, coupled with an aging workforce, presents corporations with the ongoing challenge of preserving work-related experiences and knowledge for cross-generational knowledge transfer tomore » the future workforce [5]. To prevent the D and D knowledge base and expertise from being lost over time, the DOE and the Applied Research Center at Florida International University (FIU) have developed the web-based Knowledge Management Information Tool (KM-IT) to capture and maintain this valuable information in a universally available and easily accessible and usable system. The D and D KM-IT was developed in collaboration with DOE Headquarters (HQ), the Energy Facility Contractors Group (EFCOG), and the ALARA [as low as reasonably achievable] Centers at Savannah River Sites to preserve the D and D information generated and collected by the D and D community. This is an open secured system that can be accessed from https://www.dndkm.org over the web and through mobile devices at https://m.dndkm.org. This knowledge system serves as a centralized repository and provides a common interface for D and D-related activities. It also improves efficiency by reducing the need to rediscover knowledge and promotes the reuse of existing knowledge. It is a community-driven system that facilitates the gathering, analyzing, storing, and sharing of knowledge and information within the D and D community. It assists the DOE D and D community in identifying potential solutions to their problem areas by using the vast resources and knowledge base available throughout the global D and D community. The D and D KM-IT offers a mechanism to the global D and D community for searching relevant D and D information and is focused on providing a single point of access into the collective knowledge base of the D and D community within and outside of the DOE. Collecting information from subject matter specialists, it builds a knowledge repository for future reference archiving Lessons Learned, Best Practices, ALARA reports, and other relevant documents and maintains a secured collaboration platform for the global D and D community to share knowledge. With the dynamic nature and evolution of the D and D knowledge base due to multiple factors such as changes in the workforce, new technologies and methodologies, economics, and regulations, the D and D KM-IT is being developed in a phased and modular fashion. (authors)« less
Guo, Zhi; Lin, Su; Woodbury, Neal W
2013-09-26
In photosynthetic reaction centers, the electric field generated by light-induced charge separation produces electrochromic shifts in the transitions of reaction center pigments. The extent of this Stark shift indirectly reflects the effective field strength at a particular cofactor in the complex. The dynamics of the effective field strength near the two monomeric bacteriochlorophylls (BA and BB) in purple photosynthetic bacterial reaction centers has been explored near physiological temperature by monitoring the time-dependent Stark shift during charge separation (dynamic Stark shift). This dynamic Stark shift was determined through analysis of femtosecond time-resolved absorbance change spectra recorded in wild type reaction centers and in four mutants at position M210. In both wild type and the mutants, the kinetics of the dynamic Stark shift differ from those of electron transfer, though not in the same way. In wild type, the initial electron transfer and the increase in the effective field strength near the active-side monomer bacteriochlorophyll (BA) occur in synchrony, but the two signals diverge on the time scale of electron transfer to the quinone. In contrast, when tyrosine is replaced by aspartic acid at M210, the kinetics of the BA Stark shift and the initial electron transfer differ, but transfer to the quinone coincides with the decay of the Stark shift. This is interpreted in terms of differences in the dynamics of the local dielectric environment between the mutants and the wild type. In wild type, comparison of the Stark shifts associated with BA and BB on the two quasi-symmetric halves of the reaction center structure confirm that the effective dielectric constants near these cofactors are quite different when the reaction center is in the state P(+)QA(-), as previously determined by Steffen et al. at 1.5 K (Steffen, M. A.; et al. Science 1994, 264, 810-816). However, it is not possible to determine from static, low-temperature measurments if the difference in the effective dielectric constant between the two sides of the reaction center is manifest on the time scale of initial electron transfer. By comparing directly the Stark shift dynamics of the ground-state spectra of the two monomer bacteriochlorophylls, it is evident that there is, in fact, a large dielectric difference between protein environments of the two quasi-symmetric electron-transfer branches on the time scale of initial electron transfer and that the effective dielectric constant in the region continues to evolve on a time scale of hundreds of picoseconds.
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1995-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the production and use of information by U.S. aerospace engineers and scientists who had changed their American Institute of Aeronautics and Astronautics (AIAA) membership from student to professional in the past five years.
Jack, Susan M; Brooks, Sandy; Furgal, Chris M; Dobbins, Maureen
2010-02-01
Within Canadian Aboriginal communities, the process for utilizing environmental health research evidence in the development of policies and programs is not well understood. This fundamental qualitative descriptive study explored the perceptions of 28 environmental health researchers, senior external decision-makers and decision-makers working within Aboriginal communities about factors influencing knowledge transfer and exchange, beliefs about research evidence and Traditional Knowledge and the preferred communication channels for disseminating and receiving evidence. The results indicate that collaborative relationships between researchers and decision-makers, initiated early and maintained throughout a research project, promote both the efficient conduct of a study and increase the likelihood of knowledge transfer and exchange. Participants identified that empirical research findings and Traditional Knowledge are different and distinct types of evidence that should be equally valued and used where possible to provide a holistic understanding of environmental issues and support decisions in Aboriginal communities. To facilitate the dissemination of research findings within Aboriginal communities, participants described the elements required for successfully crafting key messages, locating and using credible messengers to deliver the messages, strategies for using cultural brokers and identifying the communication channels commonly used to disseminate and receive this type of information.
Jack, Susan M.; Brooks, Sandy; Furgal, Chris M.; Dobbins, Maureen
2010-01-01
Within Canadian Aboriginal communities, the process for utilizing environmental health research evidence in the development of policies and programs is not well understood. This fundamental qualitative descriptive study explored the perceptions of 28 environmental health researchers, senior external decision-makers and decision-makers working within Aboriginal communities about factors influencing knowledge transfer and exchange, beliefs about research evidence and Traditional Knowledge and the preferred communication channels for disseminating and receiving evidence. The results indicate that collaborative relationships between researchers and decision-makers, initiated early and maintained throughout a research project, promote both the efficient conduct of a study and increase the likelihood of knowledge transfer and exchange. Participants identified that empirical research findings and Traditional Knowledge are different and distinct types of evidence that should be equally valued and used where possible to provide a holistic understanding of environmental issues and support decisions in Aboriginal communities. To facilitate the dissemination of research findings within Aboriginal communities, participants described the elements required for successfully crafting key messages, locating and using credible messengers to deliver the messages, strategies for using cultural brokers and identifying the communication channels commonly used to disseminate and receive this type of information. PMID:20616996
NASA Technical Reports Server (NTRS)
Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.
1995-01-01
The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communications practices of U.S. aerospace engineers and scientists who were assigned to the Research and Technology Group (RTG) at the NASA Langley Research Center in September 1995.
NASA Astrophysics Data System (ADS)
Tahat, Kaher; Whelan, Susan
2015-02-01
In terms of hosting countries perspectives, Foreign Direct Investments (FDI) could have a positive effect on its developing economy, by transferring, both: resources of finance in addition to the international technology (ITT) (Choi, 1997). Multinational companies (MNC) are engaging in the transferring of the new technology, internally as well as licensing older one; they create "Spillover" (Knowledge) for facilitating the transfer of ITT in line with geographical location, period of investment, and the type of industry. Furthermore, the effect of these spillovers depends on the level of transferring this knowledge based on FDI attraction policies of the host country (Huang, 2009). Considering the Arabian Gulf council countries (GCC) as "FDI- rich hosting countries", who are not seeking for financial resources, i.e., they already have a huge financial capacity for funding their different projects, even though FDI has been powerfully presented in GCC . They saw noticeable increases in FDI inflows beginning in 2002, (www.unctad.org.fdistatistics). Therefore by assumption, FDI inflows to GCC could positively affect their economic growth through transferring the advanced technology, in order to build up their level of technology (productivity growth) as well as their economic diversification strategy. If so how this Knowledge could be diffused and measured in order to maximize its benefit and enhancing the productivity growth, and what is the current status of (GCC).
O'Neill, Barbara; Parkinson, Lynne; Dwyer, Trudy; Reid-Searl, Kerry
2015-01-01
The aim is to describe nursing home nurses' perceptions around emergency transfers to hospital. Transfers are costly and traumatic for residents, and efforts are underway to avoid hospitalization. Nurses play a key role in transfers, yet their views are underreported. A systematic review of qualitative studies was undertaken, guided by Joanna Briggs Institute methods. From seven reviewed studies, it was clear nursing home nurses are challenged by the complexity of the transfer process and understand their need for appropriate clinical knowledge, skills and resources. Communication is important, yet nurses often use persuasive and targeted communication. Ambiguity, strained relationships and negative perceptions of residents' experiences around hospitalization contribute to conflict and uncertainty. Nurses are more confident when there is a plan. Transferring a resident is a complex process and special skills, knowledge and resources are required, but may be lacking. Efforts to formalize the transfer process and improve communication and collaboration amongst all stakeholders is needed and would be well received. Copyright © 2015 Elsevier Inc. All rights reserved.
McEvedy, Samantha; Maguire, Tessa; Furness, Trentham; McKenna, Brian
2017-07-01
Sensory modulation (SM) and trauma-informed-care (TIC) are therapeutic strategies which can help avoid incidents of aggression and thus reduce the use of restrictive interventions in mental health settings. In order to educate mental health nurses and allied health professionals in these strategies, a train-the-trainer intervention was developed and delivered to 19 area mental health services as a statewide, government funded program. This descriptive qualitative study evaluated the effectiveness of the intervention to: a) transfer knowledge; and, b) translate knowledge into practice. Semi-structured interviews were conducted with senior staff (n = 21); focus group discussions with trainees (n = 10); and, a paired in-depth interview with master trainers (n = 2). In total, 170 trainees attended two day train-the-trainer sessions. Many trainees were not in education roles. Most services facilitated further knowledge transfer to end-user clinicians, though training materials were often adapted. End-users' responses to SM/TIC training were generally positive to the training, but some were resistant to the change in practice. Limited anecdotal evidence of translation of SM/TIC into practice was provided. Ongoing support is required to maintain a focus on SM and TIC, sustain and encourage further knowledge transfer and translation, and assess the impact on consumer and staff health outcomes. Copyright © 2017. Published by Elsevier Ltd.
Spanning Knowledge Barriers in E-Learning Content Design
ERIC Educational Resources Information Center
Chu, Tsai-Hsin; Lee, Yi; Lee, Yen-Hsien
2013-01-01
E-learning content development can be regarded as an example of knowledge delivery process because the developers have to receive knowledge transferred from subject-matter experts (SMEs), to translate the received knowledge with appropriate instructional design, and to transform the project outcomes to fulfill learner's learning needs. As…
Knowledge Management, Human Resource Management, and Higher Education: A Theoretical Model
ERIC Educational Resources Information Center
Brewer, Peggy D.; Brewer, Kristen L.
2010-01-01
Much has been written on the importance of knowledge management, the challenges facing organizations, and the important human resource management activities involved in assuring the acquisition and transfer of knowledge. Higher business education plays an important role in preparing students to assume the knowledge management and human resource…
ERIC Educational Resources Information Center
Chen, Rui
1998-01-01
Describes the characteristics of the transfer point of information management to knowledge management (KM), what information resources management (IRM) does, and compares information and knowledge management and the roles of chief information officer (CIO) and chief knowledge officer (CKO). (PEN)
Dynamics of cavitating cascades. [transfer functions
NASA Technical Reports Server (NTRS)
Brennen, C. E.; Acosta, A. J.
1980-01-01
The unsteady dynamics of cavitating cascades and inducer pumps were studied with a view to understanding (and possibly predicting) the dynamic characteristics of these devices. The chronology of the research is summarized as well as the final conculsions for each task. The construction of a dynamic pump test facility and its use in making experimental measurements of the transfer function is described as well as tests conducted using a scale model of the low pressure liquid oxygen turbopump inducer in the shuttle main engine. Auto-oscillation and unsteady inlet flow characteristics are discussed in addition to blade cavity influence and bubbly cavitation.