Model-based restoration using light vein for range-gated imaging systems.

PubMed

Wang, Canjin; Sun, Tao; Wang, Tingfeng; Wang, Rui; Guo, Jin; Tian, Yuzhen

2016-09-10

The images captured by an airborne range-gated imaging system are degraded by many factors, such as light scattering, noise, defocus of the optical system, atmospheric disturbances, platform vibrations, and so on. The characteristics of low illumination, few details, and high noise make the state-of-the-art restoration method fail. In this paper, we present a restoration method especially for range-gated imaging systems. The degradation process is divided into two parts: the static part and the dynamic part. For the static part, we establish the physical model of the imaging system according to the laser transmission theory, and estimate the static point spread function (PSF). For the dynamic part, a so-called light vein feature extraction method is presented to estimate the fuzzy parameter of the atmospheric disturbance and platform movement, which make contributions to the dynamic PSF. Finally, combined with the static and dynamic PSF, an iterative updating framework is used to restore the image. Compared with the state-of-the-art methods, the proposed method can effectively suppress ringing artifacts and achieve better performance in a range-gated imaging system.

High dynamic range CMOS (HDRC) imagers for safety systems

NASA Astrophysics Data System (ADS)

Strobel, Markus; Döttling, Dietmar

2013-04-01

The first part of this paper describes the high dynamic range CMOS (HDRC®) imager - a special type of CMOS image sensor with logarithmic response. The powerful property of a high dynamic range (HDR) image acquisition is detailed by mathematical definition and measurement of the optoelectronic conversion function (OECF) of two different HDRC imagers. Specific sensor parameters will be discussed including the pixel design for the global shutter readout. The second part will give an outline on the applications and requirements of cameras for industrial safety. Equipped with HDRC global shutter sensors SafetyEYE® is a high-performance stereo camera system for safe three-dimensional zone monitoring enabling new and more flexible solutions compared to existing safety guards.

An Over 90 dB Intra-Scene Single-Exposure Dynamic Range CMOS Image Sensor Using a 3.0 μm Triple-Gain Pixel Fabricated in a Standard BSI Process.

PubMed

Takayanagi, Isao; Yoshimura, Norio; Mori, Kazuya; Matsuo, Shinichiro; Tanaka, Shunsuke; Abe, Hirofumi; Yasuda, Naoto; Ishikawa, Kenichiro; Okura, Shunsuke; Ohsawa, Shinji; Otaka, Toshinori

2018-01-12

To respond to the high demand for high dynamic range imaging suitable for moving objects with few artifacts, we have developed a single-exposure dynamic range image sensor by introducing a triple-gain pixel and a low noise dual-gain readout circuit. The developed 3 μm pixel is capable of having three conversion gains. Introducing a new split-pinned photodiode structure, linear full well reaches 40 ke - . Readout noise under the highest pixel gain condition is 1 e - with a low noise readout circuit. Merging two signals, one with high pixel gain and high analog gain, and the other with low pixel gain and low analog gain, a single exposure dynamic rage (SEHDR) signal is obtained. Using this technology, a 1/2.7", 2M-pixel CMOS image sensor has been developed and characterized. The image sensor also employs an on-chip linearization function, yielding a 16-bit linear signal at 60 fps, and an intra-scene dynamic range of higher than 90 dB was successfully demonstrated. This SEHDR approach inherently mitigates the artifacts from moving objects or time-varying light sources that can appear in the multiple exposure high dynamic range (MEHDR) approach.

An Over 90 dB Intra-Scene Single-Exposure Dynamic Range CMOS Image Sensor Using a 3.0 μm Triple-Gain Pixel Fabricated in a Standard BSI Process †

PubMed Central

Takayanagi, Isao; Yoshimura, Norio; Mori, Kazuya; Matsuo, Shinichiro; Tanaka, Shunsuke; Abe, Hirofumi; Yasuda, Naoto; Ishikawa, Kenichiro; Okura, Shunsuke; Ohsawa, Shinji; Otaka, Toshinori

2018-01-01

To respond to the high demand for high dynamic range imaging suitable for moving objects with few artifacts, we have developed a single-exposure dynamic range image sensor by introducing a triple-gain pixel and a low noise dual-gain readout circuit. The developed 3 μm pixel is capable of having three conversion gains. Introducing a new split-pinned photodiode structure, linear full well reaches 40 ke−. Readout noise under the highest pixel gain condition is 1 e− with a low noise readout circuit. Merging two signals, one with high pixel gain and high analog gain, and the other with low pixel gain and low analog gain, a single exposure dynamic rage (SEHDR) signal is obtained. Using this technology, a 1/2.7”, 2M-pixel CMOS image sensor has been developed and characterized. The image sensor also employs an on-chip linearization function, yielding a 16-bit linear signal at 60 fps, and an intra-scene dynamic range of higher than 90 dB was successfully demonstrated. This SEHDR approach inherently mitigates the artifacts from moving objects or time-varying light sources that can appear in the multiple exposure high dynamic range (MEHDR) approach. PMID:29329210

Reconstructing Interlaced High-Dynamic-Range Video Using Joint Learning.

PubMed

Inchang Choi; Seung-Hwan Baek; Kim, Min H

2017-11-01

For extending the dynamic range of video, it is a common practice to capture multiple frames sequentially with different exposures and combine them to extend the dynamic range of each video frame. However, this approach results in typical ghosting artifacts due to fast and complex motion in nature. As an alternative, video imaging with interlaced exposures has been introduced to extend the dynamic range. However, the interlaced approach has been hindered by jaggy artifacts and sensor noise, leading to concerns over image quality. In this paper, we propose a data-driven approach for jointly solving two specific problems of deinterlacing and denoising that arise in interlaced video imaging with different exposures. First, we solve the deinterlacing problem using joint dictionary learning via sparse coding. Since partial information of detail in differently exposed rows is often available via interlacing, we make use of the information to reconstruct details of the extended dynamic range from the interlaced video input. Second, we jointly solve the denoising problem by tailoring sparse coding to better handle additive noise in low-/high-exposure rows, and also adopt multiscale homography flow to temporal sequences for denoising. We anticipate that the proposed method will allow for concurrent capture of higher dynamic range video frames without suffering from ghosting artifacts. We demonstrate the advantages of our interlaced video imaging compared with the state-of-the-art high-dynamic-range video methods.

Multi-exposure high dynamic range image synthesis with camera shake correction

NASA Astrophysics Data System (ADS)

Li, Xudong; Chen, Yongfu; Jiang, Hongzhi; Zhao, Huijie

2017-10-01

Machine vision plays an important part in industrial online inspection. Owing to the nonuniform illuminance conditions and variable working distances, the captured image tends to be over-exposed or under-exposed. As a result, when processing the image such as crack inspection, the algorithm complexity and computing time increase. Multiexposure high dynamic range (HDR) image synthesis is used to improve the quality of the captured image, whose dynamic range is limited. Inevitably, camera shake will result in ghost effect, which blurs the synthesis image to some extent. However, existed exposure fusion algorithms assume that the input images are either perfectly aligned or captured in the same scene. These assumptions limit the application. At present, widely used registration based on Scale Invariant Feature Transform (SIFT) is usually time consuming. In order to rapidly obtain a high quality HDR image without ghost effect, we come up with an efficient Low Dynamic Range (LDR) images capturing approach and propose a registration method based on ORiented Brief (ORB) and histogram equalization which can eliminate the illumination differences between the LDR images. The fusion is performed after alignment. The experiment results demonstrate that the proposed method is robust to illumination changes and local geometric distortion. Comparing with other exposure fusion methods, our method is more efficient and can produce HDR images without ghost effect by registering and fusing four multi-exposure images.

The CAOS camera platform: ushering in a paradigm change in extreme dynamic range imager design

NASA Astrophysics Data System (ADS)

Riza, Nabeel A.

2017-02-01

Multi-pixel imaging devices such as CCD, CMOS and Focal Plane Array (FPA) photo-sensors dominate the imaging world. These Photo-Detector Array (PDA) devices certainly have their merits including increasingly high pixel counts and shrinking pixel sizes, nevertheless, they are also being hampered by limitations in instantaneous dynamic range, inter-pixel crosstalk, quantum full well capacity, signal-to-noise ratio, sensitivity, spectral flexibility, and in some cases, imager response time. Recently invented is the Coded Access Optical Sensor (CAOS) Camera platform that works in unison with current Photo-Detector Array (PDA) technology to counter fundamental limitations of PDA-based imagers while providing high enough imaging spatial resolution and pixel counts. Using for example the Texas Instruments (TI) Digital Micromirror Device (DMD) to engineer the CAOS camera platform, ushered in is a paradigm change in advanced imager design, particularly for extreme dynamic range applications.

Color transfer between high-dynamic-range images

NASA Astrophysics Data System (ADS)

Hristova, Hristina; Cozot, Rémi; Le Meur, Olivier; Bouatouch, Kadi

2015-09-01

Color transfer methods alter the look of a source image with regards to a reference image. So far, the proposed color transfer methods have been limited to low-dynamic-range (LDR) images. Unlike LDR images, which are display-dependent, high-dynamic-range (HDR) images contain real physical values of the world luminance and are able to capture high luminance variations and finest details of real world scenes. Therefore, there exists a strong discrepancy between the two types of images. In this paper, we bridge the gap between the color transfer domain and the HDR imagery by introducing HDR extensions to LDR color transfer methods. We tackle the main issues of applying a color transfer between two HDR images. First, to address the nature of light and color distributions in the context of HDR imagery, we carry out modifications of traditional color spaces. Furthermore, we ensure high precision in the quantization of the dynamic range for histogram computations. As image clustering (based on light and colors) proved to be an important aspect of color transfer, we analyze it and adapt it to the HDR domain. Our framework has been applied to several state-of-the-art color transfer methods. Qualitative experiments have shown that results obtained with the proposed adaptation approach exhibit less artifacts and are visually more pleasing than results obtained when straightforwardly applying existing color transfer methods to HDR images.

High dynamic range imaging by pupil single-mode filtering and remapping

NASA Astrophysics Data System (ADS)

Perrin, G.; Lacour, S.; Woillez, J.; Thiébaut, É.

2006-12-01

Because of atmospheric turbulence, obtaining high angular resolution images with a high dynamic range is difficult even in the near-infrared domain of wavelengths. We propose a novel technique to overcome this issue. The fundamental idea is to apply techniques developed for long baseline interferometry to the case of a single-aperture telescope. The pupil of the telescope is broken down into coherent subapertures each feeding a single-mode fibre. A remapping of the exit pupil allows interfering all subapertures non-redundantly. A diffraction-limited image with very high dynamic range is reconstructed from the fringe pattern analysis with aperture synthesis techniques, free of speckle noise. The performances of the technique are demonstrated with simulations in the visible range with an 8-m telescope. Raw dynamic ranges of 1:106 can be obtained in only a few tens of seconds of integration time for bright objects.

Forward and backward tone mapping of high dynamic range images based on subband architecture

NASA Astrophysics Data System (ADS)

Bouzidi, Ines; Ouled Zaid, Azza

2015-01-01

This paper presents a novel High Dynamic Range (HDR) tone mapping (TM) system based on sub-band architecture. Standard wavelet filters of Daubechies, Symlets, Coiflets and Biorthogonal were used to estimate the proposed system performance in terms of Low Dynamic Range (LDR) image quality and reconstructed HDR image fidelity. During TM stage, the HDR image is firstly decomposed in sub-bands using symmetrical analysis-synthesis filter bank. The transform coefficients are then rescaled using a predefined gain map. The inverse Tone Mapping (iTM) stage is straightforward. Indeed, the LDR image passes through the same sub-band architecture. But, instead of reducing the dynamic range, the LDR content is boosted to an HDR representation. Moreover, in our TM sheme, we included an optimization module to select the gain map components that minimize the reconstruction error, and consequently resulting in high fidelity HDR content. Comparisons with recent state-of-the-art methods have shown that our method provides better results in terms of visual quality and HDR reconstruction fidelity using objective and subjective evaluations.

High dynamic spectroscopy using a digital micromirror device and periodic shadowing.

PubMed

Kristensson, Elias; Ehn, Andreas; Berrocal, Edouard

2017-01-09

We present an optical solution called DMD-PS to boost the dynamic range of 2D imaging spectroscopic measurements up to 22 bits by incorporating a digital micromirror device (DMD) prior to detection in combination with the periodic shadowing (PS) approach. In contrast to high dynamic range (HDR), where the dynamic range is increased by recording several images at different exposure times, the current approach has the potential of improving the dynamic range from a single exposure and without saturation of the CCD sensor. In the procedure, the spectrum is imaged onto the DMD that selectively reduces the reflection from the intense spectral lines, allowing the signal from the weaker lines to be increased by a factor of 2⁸ via longer exposure times, higher camera gains or increased laser power. This manipulation of the spectrum can either be based on a priori knowledge of the spectrum or by first performing a calibration measurement to sense the intensity distribution. The resulting benefits in detection sensitivity come, however, at the cost of strong generation of interfering stray light. To solve this issue the Periodic Shadowing technique, which is based on spatial light modulation, is also employed. In this proof-of-concept article we describe the full methodology of DMD-PS and demonstrate - using the calibration-based concept - an improvement in dynamic range by a factor of ~100 over conventional imaging spectroscopy. The dynamic range of the presented approach will directly benefit from future technological development of DMDs and camera sensors.

Inverse Tone Mapping Based upon Retina Response

PubMed Central

Huo, Yongqing; Yang, Fan; Brost, Vincent

2014-01-01

The development of high dynamic range (HDR) display arouses the research of inverse tone mapping methods, which expand dynamic range of the low dynamic range (LDR) image to match that of HDR monitor. This paper proposed a novel physiological approach, which could avoid artifacts occurred in most existing algorithms. Inspired by the property of the human visual system (HVS), this dynamic range expansion scheme performs with a low computational complexity and a limited number of parameters and obtains high-quality HDR results. Comparisons with three recent algorithms in the literature also show that the proposed method reveals more important image details and produces less contrast loss and distortion. PMID:24744678

Rob Guglielmetti | NREL

Science.gov Websites

2009. Rob's areas of expertise are daylighting, physically based lighting simulation, the integration of lighting simulation with whole-building energy simulations, and high-dynamic range imaging. He has simulation, and high-dynamic range imaging. Rob is an advisory member of the Illuminating Engineering Society

Towards a robust HDR imaging system

NASA Astrophysics Data System (ADS)

Long, Xin; Zeng, Xiangrong; Huangpeng, Qizi; Zhou, Jinglun; Feng, Jing

2016-07-01

High dynamic range (HDR) images can show more details and luminance information in general display device than low dynamic image (LDR) images. We present a robust HDR imaging system which can deal with blurry LDR images, overcoming the limitations of most existing HDR methods. Experiments on real images show the effectiveness and competitiveness of the proposed method.

A fast and automatic fusion algorithm for unregistered multi-exposure image sequence

NASA Astrophysics Data System (ADS)

Liu, Yan; Yu, Feihong

2014-09-01

Human visual system (HVS) can visualize all the brightness levels of the scene through visual adaptation. However, the dynamic range of most commercial digital cameras and display devices are smaller than the dynamic range of human eye. This implies low dynamic range (LDR) images captured by normal digital camera may lose image details. We propose an efficient approach to high dynamic (HDR) image fusion that copes with image displacement and image blur degradation in a computationally efficient manner, which is suitable for implementation on mobile devices. The various image registration algorithms proposed in the previous literatures are unable to meet the efficiency and performance requirements in the application of mobile devices. In this paper, we selected Oriented Brief (ORB) detector to extract local image structures. The descriptor selected in multi-exposure image fusion algorithm has to be fast and robust to illumination variations and geometric deformations. ORB descriptor is the best candidate in our algorithm. Further, we perform an improved RANdom Sample Consensus (RANSAC) algorithm to reject incorrect matches. For the fusion of images, a new approach based on Stationary Wavelet Transform (SWT) is used. The experimental results demonstrate that the proposed algorithm generates high quality images at low computational cost. Comparisons with a number of other feature matching methods show that our method gets better performance.

Image-plane processing of visual information

NASA Technical Reports Server (NTRS)

Huck, F. O.; Fales, C. L.; Park, S. K.; Samms, R. W.

1984-01-01

Shannon's theory of information is used to optimize the optical design of sensor-array imaging systems which use neighborhood image-plane signal processing for enhancing edges and compressing dynamic range during image formation. The resultant edge-enhancement, or band-pass-filter, response is found to be very similar to that of human vision. Comparisons of traits in human vision with results from information theory suggest that: (1) Image-plane processing, like preprocessing in human vision, can improve visual information acquisition for pattern recognition when resolving power, sensitivity, and dynamic range are constrained. Improvements include reduced sensitivity to changes in lighter levels, reduced signal dynamic range, reduced data transmission and processing, and reduced aliasing and photosensor noise degradation. (2) Information content can be an appropriate figure of merit for optimizing the optical design of imaging systems when visual information is acquired for pattern recognition. The design trade-offs involve spatial response, sensitivity, and sampling interval.

A research on radiation calibration of high dynamic range based on the dual channel CMOS

NASA Astrophysics Data System (ADS)

Ma, Kai; Shi, Zhan; Pan, Xiaodong; Wang, Yongsheng; Wang, Jianghua

2017-10-01

The dual channel complementary metal-oxide semiconductor (CMOS) can get high dynamic range (HDR) image through extending the gray level of the image by using image fusion with high gain channel image and low gain channel image in a same frame. In the process of image fusion with dual channel, it adopts the coefficients of radiation response of a pixel from dual channel in a same frame, and then calculates the gray level of the pixel in the HDR image. For the coefficients of radiation response play a crucial role in image fusion, it has to find an effective method to acquire these parameters. In this article, it makes a research on radiation calibration of high dynamic range based on the dual channel CMOS, and designs an experiment to calibrate the coefficients of radiation response for the sensor it used. In the end, it applies these response parameters in the dual channel CMOS which calibrates, and verifies the correctness and feasibility of the method mentioned in this paper.

Nonlinear dynamic range transformation in visual communication channels.

PubMed

Alter-Gartenberg, R

1996-01-01

The article evaluates nonlinear dynamic range transformation in the context of the end-to-end continuous-input/discrete processing/continuous-display imaging process. Dynamic range transformation is required when we have the following: (i) the wide dynamic range encountered in nature is compressed into the relatively narrow dynamic range of the display, particularly for spatially varying irradiance (e.g., shadow); (ii) coarse quantization is expanded to the wider dynamic range of the display; and (iii) nonlinear tone scale transformation compensates for the correction in the camera amplifier.

High-dynamic-range imaging for cloud segmentation

NASA Astrophysics Data System (ADS)

Dev, Soumyabrata; Savoy, Florian M.; Lee, Yee Hui; Winkler, Stefan

2018-04-01

Sky-cloud images obtained from ground-based sky cameras are usually captured using a fisheye lens with a wide field of view. However, the sky exhibits a large dynamic range in terms of luminance, more than a conventional camera can capture. It is thus difficult to capture the details of an entire scene with a regular camera in a single shot. In most cases, the circumsolar region is overexposed, and the regions near the horizon are underexposed. This renders cloud segmentation for such images difficult. In this paper, we propose HDRCloudSeg - an effective method for cloud segmentation using high-dynamic-range (HDR) imaging based on multi-exposure fusion. We describe the HDR image generation process and release a new database to the community for benchmarking. Our proposed approach is the first using HDR radiance maps for cloud segmentation and achieves very good results.

Lack of robustness of textural measures obtained from 3D brain tumor MRIs impose a need for standardization.

PubMed

Molina, David; Pérez-Beteta, Julián; Martínez-González, Alicia; Martino, Juan; Velasquez, Carlos; Arana, Estanislao; Pérez-García, Víctor M

2017-01-01

Textural measures have been widely explored as imaging biomarkers in cancer. However, their robustness under dynamic range and spatial resolution changes in brain 3D magnetic resonance images (MRI) has not been assessed. The aim of this work was to study potential variations of textural measures due to changes in MRI protocols. Twenty patients harboring glioblastoma with pretreatment 3D T1-weighted MRIs were included in the study. Four different spatial resolution combinations and three dynamic ranges were studied for each patient. Sixteen three-dimensional textural heterogeneity measures were computed for each patient and configuration including co-occurrence matrices (CM) features and run-length matrices (RLM) features. The coefficient of variation was used to assess the robustness of the measures in two series of experiments corresponding to (i) changing the dynamic range and (ii) changing the matrix size. No textural measures were robust under dynamic range changes. Entropy was the only textural feature robust under spatial resolution changes (coefficient of variation under 10% in all cases). Textural measures of three-dimensional brain tumor images are not robust neither under dynamic range nor under matrix size changes. Standards should be harmonized to use textural features as imaging biomarkers in radiomic-based studies. The implications of this work go beyond the specific tumor type studied here and pose the need for standardization in textural feature calculation of oncological images.

Generation of high-dynamic range image from digital photo

NASA Astrophysics Data System (ADS)

Wang, Ying; Potemin, Igor S.; Zhdanov, Dmitry D.; Wang, Xu-yang; Cheng, Han

2016-10-01

A number of the modern applications such as medical imaging, remote sensing satellites imaging, virtual prototyping etc use the High Dynamic Range Image (HDRI). Generally to obtain HDRI from ordinary digital image the camera is calibrated. The article proposes the camera calibration method based on the clear sky as the standard light source and takes sky luminance from CIE sky model for the corresponding geographical coordinates and time. The article considers base algorithms for getting real luminance values from ordinary digital image and corresponding programmed implementation of the algorithms. Moreover, examples of HDRI reconstructed from ordinary images illustrate the article.

Design of a high-numerical-aperture digital micromirror device camera with high dynamic range.

PubMed

Qiao, Yang; Xu, Xiping; Liu, Tao; Pan, Yue

2015-01-01

A high-NA imaging system with high dynamic range is presented based on a digital micromirror device (DMD). The DMD camera consists of an objective imaging system and a relay imaging system, connected by a DMD chip. With the introduction of a total internal reflection prism system, the objective imaging system is designed with a working F/# of 1.97, breaking through the F/2.45 limitation of conventional DMD projection lenses. As for the relay imaging system, an off-axis design that could correct off-axis aberrations of the tilt relay imaging system is developed. This structure has the advantage of increasing the NA of the imaging system while maintaining a compact size. Investigation revealed that the dynamic range of a DMD camera could be greatly increased, by 2.41 times. We built one prototype DMD camera with a working F/# of 1.23, and the field experiments proved the validity and reliability our work.

Large depth of focus dynamic micro integral imaging for optical see-through augmented reality display using a focus-tunable lens.

PubMed

Shen, Xin; Javidi, Bahram

2018-03-01

We have developed a three-dimensional (3D) dynamic integral-imaging (InIm)-system-based optical see-through augmented reality display with enhanced depth range of a 3D augmented image. A focus-tunable lens is adopted in the 3D display unit to relay the elemental images with various positions to the micro lens array. Based on resolution priority integral imaging, multiple lenslet image planes are generated to enhance the depth range of the 3D image. The depth range is further increased by utilizing both the real and virtual 3D imaging fields. The 3D reconstructed image and the real-world scene are overlaid using an optical see-through display for augmented reality. The proposed system can significantly enhance the depth range of a 3D reconstructed image with high image quality in the micro InIm unit. This approach provides enhanced functionality for augmented information and adjusts the vergence-accommodation conflict of a traditional augmented reality display.

Multi exposure image fusion algorithm based on YCbCr space

NASA Astrophysics Data System (ADS)

Yang, T. T.; Fang, P. Y.

2018-05-01

To solve the problem that scene details and visual effects are difficult to be optimized in high dynamic image synthesis, we proposes a multi exposure image fusion algorithm for processing low dynamic range images in YCbCr space, and weighted blending of luminance and chromatic aberration components respectively. The experimental results show that the method can retain color effect of the fused image while balancing details of the bright and dark regions of the high dynamic image.

SpectraCAM SPM: a camera system with high dynamic range for scientific and medical applications

NASA Astrophysics Data System (ADS)

Bhaskaran, S.; Baiko, D.; Lungu, G.; Pilon, M.; VanGorden, S.

2005-08-01

A scientific camera system having high dynamic range designed and manufactured by Thermo Electron for scientific and medical applications is presented. The newly developed CID820 image sensor with preamplifier-per-pixel technology is employed in this camera system. The 4 Mega-pixel imaging sensor has a raw dynamic range of 82dB. Each high-transparent pixel is based on a preamplifier-per-pixel architecture and contains two photogates for non-destructive readout of the photon-generated charge (NDRO). Readout is achieved via parallel row processing with on-chip correlated double sampling (CDS). The imager is capable of true random pixel access with a maximum operating speed of 4MHz. The camera controller consists of a custom camera signal processor (CSP) with an integrated 16-bit A/D converter and a PowerPC-based CPU running a Linux embedded operating system. The imager is cooled to -40C via three-stage cooler to minimize dark current. The camera housing is sealed and is designed to maintain the CID820 imager in the evacuated chamber for at least 5 years. Thermo Electron has also developed custom software and firmware to drive the SpectraCAM SPM camera. Included in this firmware package is the new Extreme DRTM algorithm that is designed to extend the effective dynamic range of the camera by several orders of magnitude up to 32-bit dynamic range. The RACID Exposure graphical user interface image analysis software runs on a standard PC that is connected to the camera via Gigabit Ethernet.

Quantitative comparison between full-spectrum and filter-based imaging in hyperspectral fluorescence microscopy

PubMed Central

GAO, L.; HAGEN, N.; TKACZYK, T.S.

2012-01-01

Summary We implement a filterless illumination scheme on a hyperspectral fluorescence microscope to achieve full-range spectral imaging. The microscope employs polarisation filtering, spatial filtering and spectral unmixing filtering to replace the role of traditional filters. Quantitative comparisons between full-spectrum and filter-based microscopy are provided in the context of signal dynamic range and accuracy of measured fluorophores’ emission spectra. To show potential applications, a five-colour cell immunofluorescence imaging experiment is theoretically simulated. Simulation results indicate that the use of proposed full-spectrum imaging technique may result in three times improvement in signal dynamic range compared to that can be achieved in the filter-based imaging. PMID:22356127

Method and apparatus of high dynamic range image sensor with individual pixel reset

NASA Technical Reports Server (NTRS)

Yadid-Pecht, Orly (Inventor); Pain, Bedabrata (Inventor); Fossum, Eric R. (Inventor)

2001-01-01

A wide dynamic range image sensor provides individual pixel reset to vary the integration time of individual pixels. The integration time of each pixel is controlled by column and row reset control signals which activate a logical reset transistor only when both signals coincide for a given pixel.

Evaluation of detector dynamic range in the x-ray exposure domain in mammography: a comparison between film-screen and flat panel detector systems.

PubMed

Cooper, Virgil N; Oshiro, Thomas; Cagnon, Christopher H; Bassett, Lawrence W; McLeod-Stockmann, Tyler M; Bezrukiy, Nikita V

2003-10-01

Digital detectors in mammography have wide dynamic range in addition to the benefit of decoupled acquisition and display. How wide the dynamic range is and how it compares to film-screen systems in the clinical x-ray exposure domain are unclear. In this work, we compare the effective dynamic ranges of film-screen and flat panel mammography systems, along with the dynamic ranges of their component image receptors in the clinical x-ray exposure domain. An ACR mammography phantom was imaged using variable mAs (exposure) values for both systems. The dynamic range of the contrast-limited film-screen system was defined as that ratio of mAs (exposure) values for a 26 kVp Mo/Mo (HVL=0.34 mm Al) beam that yielded passing phantom scores. The same approach was done for the noise-limited digital system. Data from three independent observers delineated a useful phantom background optical density range of 1.27 to 2.63, which corresponded to a dynamic range of 2.3 +/- 0.53. The digital system had a dynamic range of 9.9 +/- 1.8, which was wider than the film-screen system (p<0.02). The dynamic range of the film-screen system was limited by the dynamic range of the film. The digital detector, on the other hand, had an estimated dynamic range of 42, which was wider than the dynamic range of the digital system in its entirety by a factor of 4. The generator/tube combination was the limiting factor in determining the digital system's dynamic range.

Lack of robustness of textural measures obtained from 3D brain tumor MRIs impose a need for standardization

PubMed Central

Pérez-Beteta, Julián; Martínez-González, Alicia; Martino, Juan; Velasquez, Carlos; Arana, Estanislao; Pérez-García, Víctor M.

2017-01-01

Purpose Textural measures have been widely explored as imaging biomarkers in cancer. However, their robustness under dynamic range and spatial resolution changes in brain 3D magnetic resonance images (MRI) has not been assessed. The aim of this work was to study potential variations of textural measures due to changes in MRI protocols. Materials and methods Twenty patients harboring glioblastoma with pretreatment 3D T1-weighted MRIs were included in the study. Four different spatial resolution combinations and three dynamic ranges were studied for each patient. Sixteen three-dimensional textural heterogeneity measures were computed for each patient and configuration including co-occurrence matrices (CM) features and run-length matrices (RLM) features. The coefficient of variation was used to assess the robustness of the measures in two series of experiments corresponding to (i) changing the dynamic range and (ii) changing the matrix size. Results No textural measures were robust under dynamic range changes. Entropy was the only textural feature robust under spatial resolution changes (coefficient of variation under 10% in all cases). Conclusion Textural measures of three-dimensional brain tumor images are not robust neither under dynamic range nor under matrix size changes. Standards should be harmonized to use textural features as imaging biomarkers in radiomic-based studies. The implications of this work go beyond the specific tumor type studied here and pose the need for standardization in textural feature calculation of oncological images. PMID:28586353

Swap intensified WDR CMOS module for I2/LWIR fusion

NASA Astrophysics Data System (ADS)

Ni, Yang; Noguier, Vincent

2015-05-01

The combination of high resolution visible-near-infrared low light sensor and moderate resolution uncooled thermal sensor provides an efficient way for multi-task night vision. Tremendous progress has been made on uncooled thermal sensors (a-Si, VOx, etc.). It's possible to make a miniature uncooled thermal camera module in a tiny 1cm3 cube with <1W power consumption. For silicon based solid-state low light CCD/CMOS sensors have observed also a constant progress in terms of readout noise, dark current, resolution and frame rate. In contrast to thermal sensing which is intrinsic day&night operational, the silicon based solid-state sensors are not yet capable to do the night vision performance required by defense and critical surveillance applications. Readout noise, dark current are 2 major obstacles. The low dynamic range at high sensitivity mode of silicon sensors is also an important limiting factor, which leads to recognition failure due to local or global saturations & blooming. In this context, the image intensifier based solution is still attractive for the following reasons: 1) high gain and ultra-low dark current; 2) wide dynamic range and 3) ultra-low power consumption. With high electron gain and ultra low dark current of image intensifier, the only requirement on the silicon image pickup device are resolution, dynamic range and power consumption. In this paper, we present a SWAP intensified Wide Dynamic Range CMOS module for night vision applications, especially for I2/LWIR fusion. This module is based on a dedicated CMOS image sensor using solar-cell mode photodiode logarithmic pixel design which covers a huge dynamic range (> 140dB) without saturation and blooming. The ultra-wide dynamic range image from this new generation logarithmic sensor can be used directly without any image processing and provide an instant light accommodation. The complete module is slightly bigger than a simple ANVIS format I2 tube with <500mW power consumption.

In vivo optical imaging and dynamic contrast methods for biomedical research

PubMed Central

Hillman, Elizabeth M. C.; Amoozegar, Cyrus B.; Wang, Tracy; McCaslin, Addason F. H.; Bouchard, Matthew B.; Mansfield, James; Levenson, Richard M.

2011-01-01

This paper provides an overview of optical imaging methods commonly applied to basic research applications. Optical imaging is well suited for non-clinical use, since it can exploit an enormous range of endogenous and exogenous forms of contrast that provide information about the structure and function of tissues ranging from single cells to entire organisms. An additional benefit of optical imaging that is often under-exploited is its ability to acquire data at high speeds; a feature that enables it to not only observe static distributions of contrast, but to probe and characterize dynamic events related to physiology, disease progression and acute interventions in real time. The benefits and limitations of in vivo optical imaging for biomedical research applications are described, followed by a perspective on future applications of optical imaging for basic research centred on a recently introduced real-time imaging technique called dynamic contrast-enhanced small animal molecular imaging (DyCE). PMID:22006910

Varying-energy CT imaging method based on EM-TV

NASA Astrophysics Data System (ADS)

Chen, Ping; Han, Yan

2016-11-01

For complicated structural components with wide x-ray attenuation ranges, conventional fixed-energy computed tomography (CT) imaging cannot obtain all the structural information. This limitation results in a shortage of CT information because the effective thickness of the components along the direction of x-ray penetration exceeds the limit of the dynamic range of the x-ray imaging system. To address this problem, a varying-energy x-ray CT imaging method is proposed. In this new method, the tube voltage is adjusted several times with the fixed lesser interval. Next, the fusion of grey consistency and logarithm demodulation are applied to obtain full and lower noise projection with a high dynamic range (HDR). In addition, for the noise suppression problem of the analytical method, EM-TV (expectation maximization-total Jvariation) iteration reconstruction is used. In the process of iteration, the reconstruction result obtained at one x-ray energy is used as the initial condition of the next iteration. An accompanying experiment demonstrates that this EM-TV reconstruction can also extend the dynamic range of x-ray imaging systems and provide a higher reconstruction quality relative to the fusion reconstruction method.

High dynamic range hyperspectral imaging for camouflage performance test and evaluation

NASA Astrophysics Data System (ADS)

Pearce, D.; Feenan, J.

2016-10-01

This paper demonstrates the use of high dynamic range processing applied to the specific technique of hyper-spectral imaging with linescan spectrometers. The technique provides an improvement in signal to noise for reflectance estimation. This is demonstrated for field measurements of rural imagery collected from a ground-based linescan spectrometer of rural scenes. Once fully developed, the specific application is expected to improve the colour estimation approaches and consequently the test and evaluation accuracy of camouflage performance tests. Data are presented on both field and laboratory experiments that have been used to evaluate the improvements granted by the adoption of high dynamic range data acquisition in the field of hyperspectral imaging. High dynamic ranging imaging is well suited to the hyperspectral domain due to the large variation in solar irradiance across the visible and short wave infra-red (SWIR) spectrum coupled with the wavelength dependence of the nominal silicon detector response. Under field measurement conditions it is generally impractical to provide artificial illumination; consequently, an adaptation of the hyperspectral imaging and re ectance estimation process has been developed to accommodate the solar spectrum. This is shown to improve the signal to noise ratio for the re ectance estimation process of scene materials in the 400-500 nm and 700-900 nm regions.

CAOS-CMOS camera.

PubMed

Riza, Nabeel A; La Torre, Juan Pablo; Amin, M Junaid

2016-06-13

Proposed and experimentally demonstrated is the CAOS-CMOS camera design that combines the coded access optical sensor (CAOS) imager platform with the CMOS multi-pixel optical sensor. The unique CAOS-CMOS camera engages the classic CMOS sensor light staring mode with the time-frequency-space agile pixel CAOS imager mode within one programmable optical unit to realize a high dynamic range imager for extreme light contrast conditions. The experimentally demonstrated CAOS-CMOS camera is built using a digital micromirror device, a silicon point-photo-detector with a variable gain amplifier, and a silicon CMOS sensor with a maximum rated 51.3 dB dynamic range. White light imaging of three different brightness simultaneously viewed targets, that is not possible by the CMOS sensor, is achieved by the CAOS-CMOS camera demonstrating an 82.06 dB dynamic range. Applications for the camera include industrial machine vision, welding, laser analysis, automotive, night vision, surveillance and multispectral military systems.

Gamut mapping in a high-dynamic-range color space

NASA Astrophysics Data System (ADS)

Preiss, Jens; Fairchild, Mark D.; Ferwerda, James A.; Urban, Philipp

2014-01-01

In this paper, we present a novel approach of tone mapping as gamut mapping in a high-dynamic-range (HDR) color space. High- and low-dynamic-range (LDR) images as well as device gamut boundaries can simultaneously be represented within such a color space. This enables a unified transformation of the HDR image into the gamut of an output device (in this paper called HDR gamut mapping). An additional aim of this paper is to investigate the suitability of a specific HDR color space to serve as a working color space for the proposed HDR gamut mapping. For the HDR gamut mapping, we use a recent approach that iteratively minimizes an image-difference metric subject to in-gamut images. A psychophysical experiment on an HDR display shows that the standard reproduction workflow of two subsequent transformations - tone mapping and then gamut mapping - may be improved by HDR gamut mapping.

High Dynamic Range Imaging at the Quantum Limit with Single Photon Avalanche Diode-Based Image Sensors †

PubMed Central

Mattioli Della Rocca, Francescopaolo

2018-01-01

This paper examines methods to best exploit the High Dynamic Range (HDR) of the single photon avalanche diode (SPAD) in a high fill-factor HDR photon counting pixel that is scalable to megapixel arrays. The proposed method combines multi-exposure HDR with temporal oversampling in-pixel. We present a silicon demonstration IC with 96 × 40 array of 8.25 µm pitch 66% fill-factor SPAD-based pixels achieving >100 dB dynamic range with 3 back-to-back exposures (short, mid, long). Each pixel sums 15 bit-planes or binary field images internally to constitute one frame providing 3.75× data compression, hence the 1k frames per second (FPS) output off-chip represents 45,000 individual field images per second on chip. Two future projections of this work are described: scaling SPAD-based image sensors to HDR 1 MPixel formats and shrinking the pixel pitch to 1–3 µm. PMID:29641479

Image processing pipeline for segmentation and material classification based on multispectral high dynamic range polarimetric images.

PubMed

Martínez-Domingo, Miguel Ángel; Valero, Eva M; Hernández-Andrés, Javier; Tominaga, Shoji; Horiuchi, Takahiko; Hirai, Keita

2017-11-27

We propose a method for the capture of high dynamic range (HDR), multispectral (MS), polarimetric (Pol) images of indoor scenes using a liquid crystal tunable filter (LCTF). We have included the adaptive exposure estimation (AEE) method to fully automatize the capturing process. We also propose a pre-processing method which can be applied for the registration of HDR images after they are already built as the result of combining different low dynamic range (LDR) images. This method is applied to ensure a correct alignment of the different polarization HDR images for each spectral band. We have focused our efforts in two main applications: object segmentation and classification into metal and dielectric classes. We have simplified the segmentation using mean shift combined with cluster averaging and region merging techniques. We compare the performance of our segmentation with that of Ncut and Watershed methods. For the classification task, we propose to use information not only in the highlight regions but also in their surrounding area, extracted from the degree of linear polarization (DoLP) maps. We present experimental results which proof that the proposed image processing pipeline outperforms previous techniques developed specifically for MSHDRPol image cubes.

Penrose high-dynamic-range imaging

NASA Astrophysics Data System (ADS)

Li, Jia; Bai, Chenyan; Lin, Zhouchen; Yu, Jian

2016-05-01

High-dynamic-range (HDR) imaging is becoming increasingly popular and widespread. The most common multishot HDR approach, based on multiple low-dynamic-range images captured with different exposures, has difficulties in handling camera and object movements. The spatially varying exposures (SVE) technology provides a solution to overcome this limitation by obtaining multiple exposures of the scene in only one shot but suffers from a loss in spatial resolution of the captured image. While aperiodic assignment of exposures has been shown to be advantageous during reconstruction in alleviating resolution loss, almost all the existing imaging sensors use the square pixel layout, which is a periodic tiling of square pixels. We propose the Penrose pixel layout, using pixels in aperiodic rhombus Penrose tiling, for HDR imaging. With the SVE technology, Penrose pixel layout has both exposure and pixel aperiodicities. To investigate its performance, we have to reconstruct HDR images in square pixel layout from Penrose raw images with SVE. Since the two pixel layouts are different, the traditional HDR reconstruction methods are not applicable. We develop a reconstruction method for Penrose pixel layout using a Gaussian mixture model for regularization. Both quantitative and qualitative results show the superiority of Penrose pixel layout over square pixel layout.

Hierarchical tone mapping for high dynamic range image visualization

NASA Astrophysics Data System (ADS)

Qiu, Guoping; Duan, Jiang

2005-07-01

In this paper, we present a computationally efficient, practically easy to use tone mapping techniques for the visualization of high dynamic range (HDR) images in low dynamic range (LDR) reproduction devices. The new method, termed hierarchical nonlinear linear (HNL) tone-mapping operator maps the pixels in two hierarchical steps. The first step allocates appropriate numbers of LDR display levels to different HDR intensity intervals according to the pixel densities of the intervals. The second step linearly maps the HDR intensity intervals to theirs allocated LDR display levels. In the developed HNL scheme, the assignment of LDR display levels to HDR intensity intervals is controlled by a very simple and flexible formula with a single adjustable parameter. We also show that our new operators can be used for the effective enhancement of ordinary images.

A Low-Power High-Dynamic-Range Receiver System for In-Probe 3-D Ultrasonic Imaging.

PubMed

Attarzadeh, Hourieh; Xu, Ye; Ytterdal, Trond

2017-10-01

In this paper, a dual-mode low-power, high dynamic-range receiver circuit is designed for the interface with a capacitive micromachined ultrasonic transducer. The proposed ultrasound receiver chip enables the development of an in-probe digital beamforming imaging system. The flexibility of having two operation modes offers a high dynamic range with minimum power sacrifice. A prototype of the chip containing one receive channel, with one variable transimpedance amplifier (TIA) and one analog to digital converter (ADC) circuit is implemented. Combining variable gain TIA functionality with ADC gain settings achieves an enhanced overall high dynamic range, while low power dissipation is maintained. The chip is designed and fabricated in a 65 nm standard CMOS process technology. The test chip occupies an area of 76[Formula: see text] 170 [Formula: see text]. A total average power range of 60-240 [Formula: see text] for a sampling frequency of 30 MHz, and a center frequency of 5 MHz is measured. An instantaneous dynamic range of 50.5 dB with an overall dynamic range of 72 dB is obtained from the receiver circuit.

Retinex Image Processing: Improved Fidelity To Direct Visual Observation

NASA Technical Reports Server (NTRS)

Jobson, Daniel J.; Rahman, Zia-Ur; Woodell, Glenn A.

1996-01-01

Recorded color images differ from direct human viewing by the lack of dynamic range compression and color constancy. Research is summarized which develops the center/surround retinex concept originated by Edwin Land through a single scale design to a multi-scale design with color restoration (MSRCR). The MSRCR synthesizes dynamic range compression, color constancy, and color rendition and, thereby, approaches fidelity to direct observation.

Linear dynamic range enhancement in a CMOS imager

NASA Technical Reports Server (NTRS)

Pain, Bedabrata (Inventor)

2008-01-01

A CMOS imager with increased linear dynamic range but without degradation in noise, responsivity, linearity, fixed-pattern noise, or photometric calibration comprises a linear calibrated dual gain pixel in which the gain is reduced after a pre-defined threshold level by switching in an additional capacitance. The pixel may include a novel on-pixel latch circuit that is used to switch in the additional capacitance.

Fast and High Dynamic Range Imaging with Superconducting Tunnel Junction Detectors

NASA Astrophysics Data System (ADS)

Matsuo, Hiroshi

2014-08-01

We have demonstrated a combined test of the submillimeter-wave SIS photon detectors and GaAs-JFET cryogenic integrated circuits. A relatively large background photo-current can be read out by fast-reset integrating amplifiers. An integration time of 1 ms enables fast frame rate readout and large dynamic range imaging, with an expected dynamic range of 8,000 in 1 ms. Ultimate fast and high dynamic range performance of superconducting tunnel junction detectors (STJ) will be obtained when photon counting capabilities are employed. In the terahertz frequencies, when input photon rate of 100 MHz is measured, the photon bunching gives us enough timing resolution to be used as phase information of intensity fluctuation. Application of photon statistics will be a new tool in the terahertz frequency region. The design parameters of STJ terahertz photon counting detectors are discussed.

A 4MP high-dynamic-range, low-noise CMOS image sensor

NASA Astrophysics Data System (ADS)

Ma, Cheng; Liu, Yang; Li, Jing; Zhou, Quan; Chang, Yuchun; Wang, Xinyang

2015-03-01

In this paper we present a 4 Megapixel high dynamic range, low dark noise and dark current CMOS image sensor, which is ideal for high-end scientific and surveillance applications. The pixel design is based on a 4-T PPD structure. During the readout of the pixel array, signals are first amplified, and then feed to a low- power column-parallel ADC array which is already presented in [1]. Measurement results show that the sensor achieves a dynamic range of 96dB, a dark noise of 1.47e- at 24fps speed. The dark current is 0.15e-/pixel/s at -20oC.

High-dynamic-range scene compression in humans

NASA Astrophysics Data System (ADS)

McCann, John J.

2006-02-01

Single pixel dynamic-range compression alters a particular input value to a unique output value - a look-up table. It is used in chemical and most digital photographic systems having S-shaped transforms to render high-range scenes onto low-range media. Post-receptor neural processing is spatial, as shown by the physiological experiments of Dowling, Barlow, Kuffler, and Hubel & Wiesel. Human vision does not render a particular receptor-quanta catch as a unique response. Instead, because of spatial processing, the response to a particular quanta catch can be any color. Visual response is scene dependent. Stockham proposed an approach to model human range compression using low-spatial frequency filters. Campbell, Ginsberg, Wilson, Watson, Daly and many others have developed spatial-frequency channel models. This paper describes experiments measuring the properties of desirable spatial-frequency filters for a variety of scenes. Given the radiances of each pixel in the scene and the observed appearances of objects in the image, one can calculate the visual mask for that individual image. Here, visual mask is the spatial pattern of changes made by the visual system in processing the input image. It is the spatial signature of human vision. Low-dynamic range images with many white areas need no spatial filtering. High-dynamic-range images with many blacks, or deep shadows, require strong spatial filtering. Sun on the right and shade on the left requires directional filters. These experiments show that variable scene- scenedependent filters are necessary to mimic human vision. Although spatial-frequency filters can model human dependent appearances, the problem still remains that an analysis of the scene is still needed to calculate the scene-dependent strengths of each of the filters for each frequency.

Reconfigurable metasurface aperture for security screening and microwave imaging

NASA Astrophysics Data System (ADS)

Sleasman, Timothy; Imani, Mohammadreza F.; Boyarsky, Michael; Pulido-Mancera, Laura; Reynolds, Matthew S.; Smith, David R.

2017-05-01

Microwave imaging systems have seen growing interest in recent decades for applications ranging from security screening to space/earth observation. However, hardware architectures commonly used for this purpose have not seen drastic changes. With the advent of metamaterials a wealth of opportunities have emerged for honing metasurface apertures for microwave imaging systems. Recent thrusts have introduced dynamic reconfigurability directly into the aperture layer, providing powerful capabilities from a physical layer with considerable simplicity. The waveforms generated from such dynamic metasurfaces make them suitable for application in synthetic aperture radar (SAR) and, more generally, computational imaging. In this paper, we investigate a dynamic metasurface aperture capable of performing microwave imaging in the K-band (17.5-26.5 GHz). The proposed aperture is planar and promises an inexpensive fabrication process via printed circuit board techniques. These traits are further augmented by the tunability of dynamic metasurfaces, which provides the dexterity necessary to generate field patterns ranging from a sequence of steered beams to a series of uncorrelated radiation patterns. Imaging is experimentally demonstrated with a voltage-tunable metasurface aperture. We also demonstrate the aperture's utility in real-time measurements and perform volumetric SAR imaging. The capabilities of a prototype are detailed and the future prospects of general dynamic metasurface apertures are discussed.

Polymer-Free Optode Nanosensors for Dynamic, Reversible, and Ratiometric Sodium Imaging in the Physiological Range

PubMed Central

Ruckh, Timothy T.; Mehta, Ankeeta A.; Dubach, J. Matthew; Clark, Heather A.

2013-01-01

This work introduces a polymer-free optode nanosensor for ratiometric sodium imaging. Transmembrane ion dynamics are often captured by electrophysiology and calcium imaging, but sodium dyes suffer from short excitation wavelengths and poor selectivity. Optodes, optical sensors composed of a polymer matrix with embedded sensing chemistry, have been translated into nanosensors that selectively image ion concentrations. Polymer-free nanosensors were fabricated by emulsification and were stable by diameter and sensitivity for at least one week. Ratiometric fluorescent measurements demonstrated that the nanosensors are selective for sodium over potassium by ~1.4 orders of magnitude, have a dynamic range centered at 20 mM, and are fully reversible. The ratiometric signal changes by 70% between 10 and 100 mM sodium, showing that they are sensitive to changes in sodium concentration. These nanosensors will provide a new tool for sensitive and quantitative ion imaging. PMID:24284431

High Dynamic Range Spectral Imaging Pipeline For Multispectral Filter Array Cameras.

PubMed

Lapray, Pierre-Jean; Thomas, Jean-Baptiste; Gouton, Pierre

2017-06-03

Spectral filter arrays imaging exhibits a strong similarity with color filter arrays. This permits us to embed this technology in practical vision systems with little adaptation of the existing solutions. In this communication, we define an imaging pipeline that permits high dynamic range (HDR)-spectral imaging, which is extended from color filter arrays. We propose an implementation of this pipeline on a prototype sensor and evaluate the quality of our implementation results on real data with objective metrics and visual examples. We demonstrate that we reduce noise, and, in particular we solve the problem of noise generated by the lack of energy balance. Data are provided to the community in an image database for further research.

A Novel Method to Increase LinLog CMOS Sensors’ Performance in High Dynamic Range Scenarios

PubMed Central

Martínez-Sánchez, Antonio; Fernández, Carlos; Navarro, Pedro J.; Iborra, Andrés

2011-01-01

Images from high dynamic range (HDR) scenes must be obtained with minimum loss of information. For this purpose it is necessary to take full advantage of the quantification levels provided by the CCD/CMOS image sensor. LinLog CMOS sensors satisfy the above demand by offering an adjustable response curve that combines linear and logarithmic responses. This paper presents a novel method to quickly adjust the parameters that control the response curve of a LinLog CMOS image sensor. We propose to use an Adaptive Proportional-Integral-Derivative controller to adjust the exposure time of the sensor, together with control algorithms based on the saturation level and the entropy of the images. With this method the sensor’s maximum dynamic range (120 dB) can be used to acquire good quality images from HDR scenes with fast, automatic adaptation to scene conditions. Adaptation to a new scene is rapid, with a sensor response adjustment of less than eight frames when working in real time video mode. At least 67% of the scene entropy can be retained with this method. PMID:22164083

A novel method to increase LinLog CMOS sensors' performance in high dynamic range scenarios.

PubMed

Martínez-Sánchez, Antonio; Fernández, Carlos; Navarro, Pedro J; Iborra, Andrés

2011-01-01

Images from high dynamic range (HDR) scenes must be obtained with minimum loss of information. For this purpose it is necessary to take full advantage of the quantification levels provided by the CCD/CMOS image sensor. LinLog CMOS sensors satisfy the above demand by offering an adjustable response curve that combines linear and logarithmic responses. This paper presents a novel method to quickly adjust the parameters that control the response curve of a LinLog CMOS image sensor. We propose to use an Adaptive Proportional-Integral-Derivative controller to adjust the exposure time of the sensor, together with control algorithms based on the saturation level and the entropy of the images. With this method the sensor's maximum dynamic range (120 dB) can be used to acquire good quality images from HDR scenes with fast, automatic adaptation to scene conditions. Adaptation to a new scene is rapid, with a sensor response adjustment of less than eight frames when working in real time video mode. At least 67% of the scene entropy can be retained with this method.

A CMOS image sensor with programmable pixel-level analog processing.

PubMed

Massari, Nicola; Gottardi, Massimo; Gonzo, Lorenzo; Stoppa, David; Simoni, Andrea

2005-11-01

A prototype of a 34 x 34 pixel image sensor, implementing real-time analog image processing, is presented. Edge detection, motion detection, image amplification, and dynamic-range boosting are executed at pixel level by means of a highly interconnected pixel architecture based on the absolute value of the difference among neighbor pixels. The analog operations are performed over a kernel of 3 x 3 pixels. The square pixel, consisting of 30 transistors, has a pitch of 35 microm with a fill-factor of 20%. The chip was fabricated in a 0.35 microm CMOS technology, and its power consumption is 6 mW with 3.3 V power supply. The device was fully characterized and achieves a dynamic range of 50 dB with a light power density of 150 nW/mm2 and a frame rate of 30 frame/s. The measured fixed pattern noise corresponds to 1.1% of the saturation level. The sensor's dynamic range can be extended up to 96 dB using the double-sampling technique.

Time-resolved multi-mass ion imaging: Femtosecond UV-VUV pump-probe spectroscopy with the PImMS camera.

PubMed

Forbes, Ruaridh; Makhija, Varun; Veyrinas, Kévin; Stolow, Albert; Lee, Jason W L; Burt, Michael; Brouard, Mark; Vallance, Claire; Wilkinson, Iain; Lausten, Rune; Hockett, Paul

2017-07-07

The Pixel-Imaging Mass Spectrometry (PImMS) camera allows for 3D charged particle imaging measurements, in which the particle time-of-flight is recorded along with (x, y) position. Coupling the PImMS camera to an ultrafast pump-probe velocity-map imaging spectroscopy apparatus therefore provides a route to time-resolved multi-mass ion imaging, with both high count rates and large dynamic range, thus allowing for rapid measurements of complex photofragmentation dynamics. Furthermore, the use of vacuum ultraviolet wavelengths for the probe pulse allows for an enhanced observation window for the study of excited state molecular dynamics in small polyatomic molecules having relatively high ionization potentials. Herein, preliminary time-resolved multi-mass imaging results from C 2 F 3 I photolysis are presented. The experiments utilized femtosecond VUV and UV (160.8 nm and 267 nm) pump and probe laser pulses in order to demonstrate and explore this new time-resolved experimental ion imaging configuration. The data indicate the depth and power of this measurement modality, with a range of photofragments readily observed, and many indications of complex underlying wavepacket dynamics on the excited state(s) prepared.

Modeling a color-rendering operator for high dynamic range images using a cone-response function

NASA Astrophysics Data System (ADS)

Choi, Ho-Hyoung; Kim, Gi-Seok; Yun, Byoung-Ju

2015-09-01

Tone-mapping operators are the typical algorithms designed to produce visibility and the overall impression of brightness, contrast, and color of high dynamic range (HDR) images on low dynamic range (LDR) display devices. Although several new tone-mapping operators have been proposed in recent years, the results of these operators have not matched those of the psychophysical experiments based on the human visual system. A color-rendering model that is a combination of tone-mapping and cone-response functions using an XYZ tristimulus color space is presented. In the proposed method, the tone-mapping operator produces visibility and the overall impression of brightness, contrast, and color in HDR images when mapped onto relatively LDR devices. The tone-mapping resultant image is obtained using chromatic and achromatic colors to avoid well-known color distortions shown in the conventional methods. The resulting image is then processed with a cone-response function wherein emphasis is placed on human visual perception (HVP). The proposed method covers the mismatch between the actual scene and the rendered image based on HVP. The experimental results show that the proposed method yields an improved color-rendering performance compared to conventional methods.

Prediction of Viking lander camera image quality

NASA Technical Reports Server (NTRS)

Huck, F. O.; Burcher, E. E.; Jobson, D. J.; Wall, S. D.

1976-01-01

Formulations are presented that permit prediction of image quality as a function of camera performance, surface radiance properties, and lighting and viewing geometry. Predictions made for a wide range of surface radiance properties reveal that image quality depends strongly on proper camera dynamic range command and on favorable lighting and viewing geometry. Proper camera dynamic range commands depend mostly on the surface albedo that will be encountered. Favorable lighting and viewing geometries depend mostly on lander orientation with respect to the diurnal sun path over the landing site, and tend to be independent of surface albedo and illumination scattering function. Side lighting with low sun elevation angles (10 to 30 deg) is generally favorable for imaging spatial details and slopes, whereas high sun elevation angles are favorable for measuring spectral reflectances.

A NOISE ADAPTIVE FUZZY EQUALIZATION METHOD FOR PROCESSING SOLAR EXTREME ULTRAVIOLET IMAGES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Druckmueller, M., E-mail: druckmuller@fme.vutbr.cz

A new image enhancement tool ideally suited for the visualization of fine structures in extreme ultraviolet images of the corona is presented in this paper. The Noise Adaptive Fuzzy Equalization method is particularly suited for the exceptionally high dynamic range images from the Atmospheric Imaging Assembly instrument on the Solar Dynamics Observatory. This method produces artifact-free images and gives significantly better results than methods based on convolution or Fourier transform which are often used for that purpose.

Generalized assorted pixel camera: postcapture control of resolution, dynamic range, and spectrum.

PubMed

Yasuma, Fumihito; Mitsunaga, Tomoo; Iso, Daisuke; Nayar, Shree K

2010-09-01

We propose the concept of a generalized assorted pixel (GAP) camera, which enables the user to capture a single image of a scene and, after the fact, control the tradeoff between spatial resolution, dynamic range and spectral detail. The GAP camera uses a complex array (or mosaic) of color filters. A major problem with using such an array is that the captured image is severely under-sampled for at least some of the filter types. This leads to reconstructed images with strong aliasing. We make four contributions in this paper: 1) we present a comprehensive optimization method to arrive at the spatial and spectral layout of the color filter array of a GAP camera. 2) We develop a novel algorithm for reconstructing the under-sampled channels of the image while minimizing aliasing artifacts. 3) We demonstrate how the user can capture a single image and then control the tradeoff of spatial resolution to generate a variety of images, including monochrome, high dynamic range (HDR) monochrome, RGB, HDR RGB, and multispectral images. 4) Finally, the performance of our GAP camera has been verified using extensive simulations that use multispectral images of real world scenes. A large database of these multispectral images has been made available at http://www1.cs.columbia.edu/CAVE/projects/gap_camera/ for use by the research community.

A Wide Dynamic Range Tapped Linear Array Image Sensor

NASA Astrophysics Data System (ADS)

Washkurak, William D.; Chamberlain, Savvas G.; Prince, N. Daryl

1988-08-01

Detectors for acousto-optic signal processing applications require fast transient response as well as wide dynamic range. There are two major choices of detectors: conductive or integration mode. Conductive mode detectors have an initial transient period before they reach then' i equilibrium state. The duration of 1 his period is dependent on light level as well as detector capacitance. At low light levels a conductive mode detector is very slow; response time is typically on the order of milliseconds. Generally. to obtain fast transient response an integrating mode detector is preferred. With integrating mode detectors. the dynamic range is determined by the charge storage capability of the tran-sport shift registers and the noise level of the image sensor. The conventional net hod used to improve dynamic range is to increase the shift register charge storage capability. To achieve a dynamic range of fifty thousand assuming two hundred noise equivalent electrons, a charge storage capability of ten million electrons would be required. In order to accommodate this amount of charge. unrealistic shift registers widths would be required. Therefore, with an integrating mode detector it is difficult to achieve a dynamic range of over four orders of magnitude of input light intensity. Another alternative is to solve the problem at the photodetector aml not the shift, register. DALSA's wide dynamic range detector utilizes an optimized, ion implant doped, profiled MOSFET photodetector specifically designed for wide dynamic range. When this new detector operates at high speed and at low light levels the photons are collected and stored in an integrating fashion. However. at bright light levels where transient periods are short, the detector switches into a conductive mode. The light intensity is logarithmically compressed into small charge packets, easily carried by the CCD shift register. As a result of the logarithmic conversion, dynamic ranges of over six orders of magnitide are obtained. To achieve the short integration times necessary in acousto-optic applications. t he wide dynamic range detector has been implemented into a tapped array architecture with eight outputs and 256 photoelements. Operation of each 01)1,1)111 at 16 MHz yields detector integration times of 2 micro-seconds. Buried channel two phase CCD shift register technology is utilized to minimize image sensor noise improve video output rates and increase ease of operation.

Land Cover Classification of the Jornada Experimental Range with Simulated HyspIRI Data

NASA Astrophysics Data System (ADS)

Thorp, K. R.; French, A. N.

2011-12-01

The proposed NASA mission, HyspIRI, would facilitate the use of hyperspectral satellite remote sensing images for monitoring a variety of Earth system processes. We utilized four years of AVIRIS data of the USDA Jornada Experimental Range in southern New Mexico to simulate the visible and near-infrared bands of the planned HyspIRI satellite. Vegetation dynamics at Jornada has been the subject of several recent studies due to concerns of invasive plant species encroaching on native rangeland grasses. Our objective was to assess the added value of simulated HyspIRI images to appropriately classify rangeland vegetation. The AVIRIS images were georeferenced to an orthophoto of the region and 's6' was implemented for atmospheric correction. Images were resampled to simulate HyspIRI wavebands in the visible and near-infrared. Supervised image classification based on observed spectra of rangeland vegetation species was used to map spatial vegetation cover class and temporal dynamics over four years. Forthcoming results will identify the added value of hyperspectral images, as compared to broadband images, for monitoring vegetation dynamics at Jornada.

High-dynamic-range coherent diffractive imaging: ptychography using the mixed-mode pixel array detector

PubMed Central

Giewekemeyer, Klaus; Philipp, Hugh T.; Wilke, Robin N.; Aquila, Andrew; Osterhoff, Markus; Tate, Mark W.; Shanks, Katherine S.; Zozulya, Alexey V.; Salditt, Tim; Gruner, Sol M.; Mancuso, Adrian P.

2014-01-01

Coherent (X-ray) diffractive imaging (CDI) is an increasingly popular form of X-ray microscopy, mainly due to its potential to produce high-resolution images and the lack of an objective lens between the sample and its corresponding imaging detector. One challenge, however, is that very high dynamic range diffraction data must be collected to produce both quantitative and high-resolution images. In this work, hard X-ray ptychographic coherent diffractive imaging has been performed at the P10 beamline of the PETRA III synchrotron to demonstrate the potential of a very wide dynamic range imaging X-ray detector (the Mixed-Mode Pixel Array Detector, or MM-PAD). The detector is capable of single photon detection, detecting fluxes exceeding 1 × 108 8-keV photons pixel−1 s−1, and framing at 1 kHz. A ptychographic reconstruction was performed using a peak focal intensity on the order of 1 × 1010 photons µm−2 s−1 within an area of approximately 325 nm × 603 nm. This was done without need of a beam stop and with a very modest attenuation, while ‘still’ images of the empty beam far-field intensity were recorded without any attenuation. The treatment of the detector frames and CDI methodology for reconstruction of non-sensitive detector regions, partially also extending the active detector area, are described. PMID:25178008

High-dynamic-range coherent diffractive imaging: ptychography using the mixed-mode pixel array detector.

PubMed

Giewekemeyer, Klaus; Philipp, Hugh T; Wilke, Robin N; Aquila, Andrew; Osterhoff, Markus; Tate, Mark W; Shanks, Katherine S; Zozulya, Alexey V; Salditt, Tim; Gruner, Sol M; Mancuso, Adrian P

2014-09-01

Coherent (X-ray) diffractive imaging (CDI) is an increasingly popular form of X-ray microscopy, mainly due to its potential to produce high-resolution images and the lack of an objective lens between the sample and its corresponding imaging detector. One challenge, however, is that very high dynamic range diffraction data must be collected to produce both quantitative and high-resolution images. In this work, hard X-ray ptychographic coherent diffractive imaging has been performed at the P10 beamline of the PETRA III synchrotron to demonstrate the potential of a very wide dynamic range imaging X-ray detector (the Mixed-Mode Pixel Array Detector, or MM-PAD). The detector is capable of single photon detection, detecting fluxes exceeding 1 × 10(8) 8-keV photons pixel(-1) s(-1), and framing at 1 kHz. A ptychographic reconstruction was performed using a peak focal intensity on the order of 1 × 10(10) photons µm(-2) s(-1) within an area of approximately 325 nm × 603 nm. This was done without need of a beam stop and with a very modest attenuation, while `still' images of the empty beam far-field intensity were recorded without any attenuation. The treatment of the detector frames and CDI methodology for reconstruction of non-sensitive detector regions, partially also extending the active detector area, are described.

Color sensitivity of the multi-exposure HDR imaging process

NASA Astrophysics Data System (ADS)

Lenseigne, Boris; Jacobs, Valéry Ann; Withouck, Martijn; Hanselaer, Peter; Jonker, Pieter P.

2013-04-01

Multi-exposure high dynamic range(HDR) imaging builds HDR radiance maps by stitching together different views of a same scene with varying exposures. Practically, this process involves converting raw sensor data into low dynamic range (LDR) images, estimate the camera response curves, and use them in order to recover the irradiance for every pixel. During the export, applying white balance settings and image stitching, which both have an influence on the color balance in the final image. In this paper, we use a calibrated quasi-monochromatic light source, an integrating sphere, and a spectrograph in order to evaluate and compare the average spectral response of the image sensor. We finally draw some conclusion about the color consistency of HDR imaging and the additional steps necessary to use multi-exposure HDR imaging as a tool to measure the physical quantities such as radiance and luminance.

An improved triangulation laser rangefinder using a custom CMOS HDR linear image sensor

NASA Astrophysics Data System (ADS)

Liscombe, Michael

3-D triangulation laser rangefinders are used in many modern applications, from terrain mapping to biometric identification. Although a wide variety of designs have been proposed, laser speckle noise still provides a fundamental limitation on range accuracy. These works propose a new triangulation laser rangefinder designed specifically to mitigate the effects of laser speckle noise. The proposed rangefinder uses a precision linear translator to laterally reposition the imaging system (e.g., image sensor and imaging lens). For a given spatial location of the laser spot, capturing N spatially uncorrelated laser spot profiles is shown to improve range accuracy by a factor of N . This technique has many advantages over past speckle-reduction technologies, such as a fixed system cost and form factor, and the ability to virtually eliminate laser speckle noise. These advantages are made possible through spatial diversity and come at the cost of increased acquisition time. The rangefinder makes use of the ICFYKWG1 linear image sensor, a custom CMOS sensor developed at the Vision Sensor Laboratory (York University). Tests are performed on the image sensor's innovative high dynamic range technology to determine its effects on range accuracy. As expected, experimental results have shown that the sensor provides a trade-off between dynamic range and range accuracy.

Evaluation of a HDR image sensor with logarithmic response for mobile video-based applications

NASA Astrophysics Data System (ADS)

Tektonidis, Marco; Pietrzak, Mateusz; Monnin, David

2017-10-01

The performance of mobile video-based applications using conventional LDR (Low Dynamic Range) image sensors highly depends on the illumination conditions. As an alternative, HDR (High Dynamic Range) image sensors with logarithmic response are capable to acquire illumination-invariant HDR images in a single shot. We have implemented a complete image processing framework for a HDR sensor, including preprocessing methods (nonuniformity correction (NUC), cross-talk correction (CTC), and demosaicing) as well as tone mapping (TM). We have evaluated the HDR sensor for video-based applications w.r.t. the display of images and w.r.t. image analysis techniques. Regarding the display we have investigated the image intensity statistics over time, and regarding image analysis we assessed the number of feature correspondences between consecutive frames of temporal image sequences. For the evaluation we used HDR image data recorded from a vehicle on outdoor or combined outdoor/indoor itineraries, and we performed a comparison with corresponding conventional LDR image data.

An Integrated Tone Mapping for High Dynamic Range Image Visualization

NASA Astrophysics Data System (ADS)

Liang, Lei; Pan, Jeng-Shyang; Zhuang, Yongjun

2018-01-01

There are two type tone mapping operators for high dynamic range (HDR) image visualization. HDR image mapped by perceptual operators have strong sense of reality, but will lose local details. Empirical operators can maximize local detail information of HDR image, but realism is not strong. A common tone mapping operator suitable for all applications is not available. This paper proposes a novel integrated tone mapping framework which can achieve conversion between empirical operators and perceptual operators. In this framework, the empirical operator is rendered based on improved saliency map, which simulates the visual attention mechanism of the human eye to the natural scene. The results of objective evaluation prove the effectiveness of the proposed solution.

High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts

NASA Astrophysics Data System (ADS)

Yang, Victor X. D.; Gordon, Maggie L.; Tang, Shou-Jiang; Marcon, Norman E.; Gardiner, Geoffrey; Qi, Bing; Bisland, Stuart; Seng-Yue, Emily; Lo, Stewart; Pekar, Julius; Wilson, Brian C.; Vitkin, I. Alex

2003-09-01

We previously described a fiber based Doppler optical coherence tomography system [1] capable of imaging embryo cardiac blood flow at 4~16 frames per second with wide velocity dynamic range [2]. Coupling this system to a linear scanning fiber optical catheter design that minimizes friction and vibrations, we report here the initial results of in vivo endoscopic Doppler optical coherence tomography (EDOCT) imaging in normal rat and human esophagus. Microvascular flow in blood vessels less than 100 µm diameter was detected using a combination of color-Doppler and velocity variance imaging modes, during clinical endoscopy using a mobile EDOCT system.

Pseudo-color coding method for high-dynamic single-polarization SAR images

NASA Astrophysics Data System (ADS)

Feng, Zicheng; Liu, Xiaolin; Pei, Bingzhi

2018-04-01

A raw synthetic aperture radar (SAR) image usually has a 16-bit or higher bit depth, which cannot be directly visualized on 8-bit displays. In this study, we propose a pseudo-color coding method for high-dynamic singlepolarization SAR images. The method considers the characteristics of both SAR images and human perception. In HSI (hue, saturation and intensity) color space, the method carries out high-dynamic range tone mapping and pseudo-color processing simultaneously in order to avoid loss of details and to improve object identifiability. It is a highly efficient global algorithm.

Perceptual Contrast Enhancement with Dynamic Range Adjustment

PubMed Central

Zhang, Hong; Li, Yuecheng; Chen, Hao; Yuan, Ding; Sun, Mingui

2013-01-01

Recent years, although great efforts have been made to improve its performance, few Histogram equalization (HE) methods take human visual perception (HVP) into account explicitly. The human visual system (HVS) is more sensitive to edges than brightness. This paper proposes to take use of this nature intuitively and develops a perceptual contrast enhancement approach with dynamic range adjustment through histogram modification. The use of perceptual contrast connects the image enhancement problem with the HVS. To pre-condition the input image before the HE procedure is implemented, a perceptual contrast map (PCM) is constructed based on the modified Difference of Gaussian (DOG) algorithm. As a result, the contrast of the image is sharpened and high frequency noise is suppressed. A modified Clipped Histogram Equalization (CHE) is also developed which improves visual quality by automatically detecting the dynamic range of the image with improved perceptual contrast. Experimental results show that the new HE algorithm outperforms several state-of-the-art algorithms in improving perceptual contrast and enhancing details. In addition, the new algorithm is simple to implement, making it suitable for real-time applications. PMID:24339452

Evaluation of privacy in high dynamic range video sequences

NASA Astrophysics Data System (ADS)

Řeřábek, Martin; Yuan, Lin; Krasula, Lukáš; Korshunov, Pavel; Fliegel, Karel; Ebrahimi, Touradj

2014-09-01

The ability of high dynamic range (HDR) to capture details in environments with high contrast has a significant impact on privacy in video surveillance. However, the extent to which HDR imaging affects privacy, when compared to a typical low dynamic range (LDR) imaging, is neither well studied nor well understood. To achieve such an objective, a suitable dataset of images and video sequences is needed. Therefore, we have created a publicly available dataset of HDR video for privacy evaluation PEViD-HDR, which is an HDR extension of an existing Privacy Evaluation Video Dataset (PEViD). PEViD-HDR video dataset can help in the evaluations of privacy protection tools, as well as for showing the importance of HDR imaging in video surveillance applications and its influence on the privacy-intelligibility trade-off. We conducted a preliminary subjective experiment demonstrating the usability of the created dataset for evaluation of privacy issues in video. The results confirm that a tone-mapped HDR video contains more privacy sensitive information and details compared to a typical LDR video.

Context-dependent JPEG backward-compatible high-dynamic range image compression

NASA Astrophysics Data System (ADS)

Korshunov, Pavel; Ebrahimi, Touradj

2013-10-01

High-dynamic range (HDR) imaging is expected, together with ultrahigh definition and high-frame rate video, to become a technology that may change photo, TV, and film industries. Many cameras and displays capable of capturing and rendering both HDR images and video are already available in the market. The popularity and full-public adoption of HDR content is, however, hindered by the lack of standards in evaluation of quality, file formats, and compression, as well as large legacy base of low-dynamic range (LDR) displays that are unable to render HDR. To facilitate the wide spread of HDR usage, the backward compatibility of HDR with commonly used legacy technologies for storage, rendering, and compression of video and images are necessary. Although many tone-mapping algorithms are developed for generating viewable LDR content from HDR, there is no consensus of which algorithm to use and under which conditions. We, via a series of subjective evaluations, demonstrate the dependency of the perceptual quality of the tone-mapped LDR images on the context: environmental factors, display parameters, and image content itself. Based on the results of subjective tests, it proposes to extend JPEG file format, the most popular image format, in a backward compatible manner to deal with HDR images also. An architecture to achieve such backward compatibility with JPEG is proposed. A simple implementation of lossy compression demonstrates the efficiency of the proposed architecture compared with the state-of-the-art HDR image compression.

Analog signal processing for optical coherence imaging systems

NASA Astrophysics Data System (ADS)

Xu, Wei

Optical coherence tomography (OCT) and optical coherence microscopy (OCM) are non-invasive optical coherence imaging techniques, which enable micron-scale resolution, depth resolved imaging capability. Both OCT and OCM are based on Michelson interferometer theory. They are widely used in ophthalmology, gastroenterology and dermatology, because of their high resolution, safety and low cost. OCT creates cross sectional images whereas OCM obtains en face images. In this dissertation, the design and development of three increasingly complicated analog signal processing (ASP) solutions for optical coherence imaging are presented. The first ASP solution was implemented for a time domain OCT system with a Rapid Scanning Optical Delay line (RSOD)-based optical signal modulation and logarithmic amplifier (Log amp) based demodulation. This OCT system can acquire up to 1600 A-scans per second. The measured dynamic range is 106dB at 200A-scan per second. This OCT signal processing electronics includes an off-the-shelf filter box with a Log amp circuit implemented on a PCB board. The second ASP solution was developed for an OCM system with synchronized modulation and demodulation and compensation for interferometer phase drift. This OCM acquired micron-scale resolution, high dynamic range images at acquisition speeds up to 45,000 pixels/second. This OCM ASP solution is fully custom designed on a perforated circuit board. The third ASP solution was implemented on a single 2.2 mm x 2.2 mm complementary metal oxide semiconductor (CMOS) chip. This design is expandable to a multiple channel OCT system. A single on-chip CMOS photodetector and ASP channel was used for coherent demodulation in a time domain OCT system. Cross-sectional images were acquired with a dynamic range of 76dB (limited by photodetector responsivity). When incorporated with a bump-bonded InGaAs photodiode with higher responsivity, the expected dynamic range is close to 100dB.

New segmentation-based tone mapping algorithm for high dynamic range image

NASA Astrophysics Data System (ADS)

Duan, Weiwei; Guo, Huinan; Zhou, Zuofeng; Huang, Huimin; Cao, Jianzhong

2017-07-01

The traditional tone mapping algorithm for the display of high dynamic range (HDR) image has the drawback of losing the impression of brightness, contrast and color information. To overcome this phenomenon, we propose a new tone mapping algorithm based on dividing the image into different exposure regions in this paper. Firstly, the over-exposure region is determined using the Local Binary Pattern information of HDR image. Then, based on the peak and average gray of the histogram, the under-exposure and normal-exposure region of HDR image are selected separately. Finally, the different exposure regions are mapped by differentiated tone mapping methods to get the final result. The experiment results show that the proposed algorithm achieve the better performance both in visual quality and objective contrast criterion than other algorithms.

Ghost detection and removal based on super-pixel grouping in exposure fusion

NASA Astrophysics Data System (ADS)

Jiang, Shenyu; Xu, Zhihai; Li, Qi; Chen, Yueting; Feng, Huajun

2014-09-01

A novel multi-exposure images fusion method for dynamic scenes is proposed. The commonly used techniques for high dynamic range (HDR) imaging are based on the combination of multiple differently exposed images of the same scene. The drawback of these methods is that ghosting artifacts will be introduced into the final HDR image if the scene is not static. In this paper, a super-pixel grouping based method is proposed to detect the ghost in the image sequences. We introduce the zero mean normalized cross correlation (ZNCC) as a measure of similarity between a given exposure image and the reference. The calculation of ZNCC is implemented in super-pixel level, and the super-pixels which have low correlation with the reference are excluded by adjusting the weight maps for fusion. Without any prior information on camera response function or exposure settings, the proposed method generates low dynamic range (LDR) images which can be shown on conventional display devices directly with details preserving and ghost effects reduced. Experimental results show that the proposed method generates high quality images which have less ghost artifacts and provide a better visual quality than previous approaches.

Evaluation of color encodings for high dynamic range pixels

NASA Astrophysics Data System (ADS)

Boitard, Ronan; Mantiuk, Rafal K.; Pouli, Tania

2015-03-01

Traditional Low Dynamic Range (LDR) color spaces encode a small fraction of the visible color gamut, which does not encompass the range of colors produced on upcoming High Dynamic Range (HDR) displays. Future imaging systems will require encoding much wider color gamut and luminance range. Such wide color gamut can be represented using floating point HDR pixel values but those are inefficient to encode. They also lack perceptual uniformity of the luminance and color distribution, which is provided (in approximation) by most LDR color spaces. Therefore, there is a need to devise an efficient, perceptually uniform and integer valued representation for high dynamic range pixel values. In this paper we evaluate several methods for encoding colour HDR pixel values, in particular for use in image and video compression. Unlike other studies we test both luminance and color difference encoding in a rigorous 4AFC threshold experiments to determine the minimum bit-depth required. Results show that the Perceptual Quantizer (PQ) encoding provides the best perceptual uniformity in the considered luminance range, however the gain in bit-depth is rather modest. More significant difference can be observed between color difference encoding schemes, from which YDuDv encoding seems to be the most efficient.

Doppler imaging with dual-detection full-range frequency domain optical coherence tomography

PubMed Central

Meemon, Panomsak; Lee, Kye-Sung; Rolland, Jannick P.

2010-01-01

Most of full-range techniques for Frequency Domain Optical Coherence Tomography (FD-OCT) reported to date utilize the phase relation between consecutive axial lines to reconstruct a complex interference signal and hence may exhibit degradation in either mirror image suppression performance or detectable velocity dynamic range or both when monitoring a moving sample such as flow activity. We have previously reported a technique of mirror image removal by simultaneous detection of the quadrature components of a complex spectral interference called a Dual-Detection Frequency Domain OCT (DD-FD-OCT) [Opt. Lett. 35, 1058-1060 (2010)]. The technique enables full range imaging without any loss of acquisition speed and is intrinsically less sensitive to phase errors generated by involuntary movements of the subject. In this paper, we demonstrate the application of the DD-FD-OCT to a phase-resolved Doppler imaging without degradation in either mirror image suppression performance or detectable velocity dynamic range that were observed in other full-range Doppler methods. In order to accommodate for Doppler imaging, we have developed a fiber-based DD-FD-OCT that more efficiently utilizes the source power compared with the previous free-space DD-FD-OCT. In addition, the velocity sensitivity of the phase-resolved DD-FD-OCT was investigated, and the relation between the measured Doppler phase shift and set flow velocity of a flow phantom was verified. Finally, we demonstrate the Doppler imaging using the DD-FD-OCT in a biological sample. PMID:21258488

Imaging multi-scale dynamics in vivo with spiral volumetric optoacoustic tomography

NASA Astrophysics Data System (ADS)

Deán-Ben, X. Luís.; Fehm, Thomas F.; Ford, Steven J.; Gottschalk, Sven; Razansky, Daniel

2017-03-01

Imaging dynamics in living organisms is essential for the understanding of biological complexity. While multiple imaging modalities are often required to cover both microscopic and macroscopic spatial scales, dynamic phenomena may also extend over different temporal scales, necessitating the use of different imaging technologies based on the trade-off between temporal resolution and effective field of view. Optoacoustic (photoacoustic) imaging has been shown to offer the exclusive capability to link multiple spatial scales ranging from organelles to entire organs of small animals. Yet, efficient visualization of multi-scale dynamics remained difficult with state-of-the-art systems due to inefficient trade-offs between image acquisition and effective field of view. Herein, we introduce a spiral volumetric optoacoustic tomography (SVOT) technique that provides spectrally-enriched high-resolution optical absorption contrast across multiple spatio-temporal scales. We demonstrate that SVOT can be used to monitor various in vivo dynamics, from video-rate volumetric visualization of cardiac-associated motion in whole organs to high-resolution imaging of pharmacokinetics in larger regions. The multi-scale dynamic imaging capability thus emerges as a powerful and unique feature of the optoacoustic technology that adds to the multiple advantages of this technology for structural, functional and molecular imaging.

Characterization of 3-Dimensional PET Systems for Accurate Quantification of Myocardial Blood Flow.

PubMed

Renaud, Jennifer M; Yip, Kathy; Guimond, Jean; Trottier, Mikaël; Pibarot, Philippe; Turcotte, Eric; Maguire, Conor; Lalonde, Lucille; Gulenchyn, Karen; Farncombe, Troy; Wisenberg, Gerald; Moody, Jonathan; Lee, Benjamin; Port, Steven C; Turkington, Timothy G; Beanlands, Rob S; deKemp, Robert A

2017-01-01

Three-dimensional (3D) mode imaging is the current standard for PET/CT systems. Dynamic imaging for quantification of myocardial blood flow with short-lived tracers, such as 82 Rb-chloride, requires accuracy to be maintained over a wide range of isotope activities and scanner counting rates. We proposed new performance standard measurements to characterize the dynamic range of PET systems for accurate quantitative imaging. 82 Rb or 13 N-ammonia (1,100-3,000 MBq) was injected into the heart wall insert of an anthropomorphic torso phantom. A decaying isotope scan was obtained over 5 half-lives on 9 different 3D PET/CT systems and 1 3D/2-dimensional PET-only system. Dynamic images (28 × 15 s) were reconstructed using iterative algorithms with all corrections enabled. Dynamic range was defined as the maximum activity in the myocardial wall with less than 10% bias, from which corresponding dead-time, counting rates, and/or injected activity limits were established for each scanner. Scatter correction residual bias was estimated as the maximum cavity blood-to-myocardium activity ratio. Image quality was assessed via the coefficient of variation measuring nonuniformity of the left ventricular myocardium activity distribution. Maximum recommended injected activity/body weight, peak dead-time correction factor, counting rates, and residual scatter bias for accurate cardiac myocardial blood flow imaging were 3-14 MBq/kg, 1.5-4.0, 22-64 Mcps singles and 4-14 Mcps prompt coincidence counting rates, and 2%-10% on the investigated scanners. Nonuniformity of the myocardial activity distribution varied from 3% to 16%. Accurate dynamic imaging is possible on the 10 3D PET systems if the maximum injected MBq/kg values are respected to limit peak dead-time losses during the bolus first-pass transit. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

A Multiscale Vision Model applied to analyze EIT images of the solar corona

NASA Astrophysics Data System (ADS)

Portier-Fozzani, F.; Vandame, B.; Bijaoui, A.; Maucherat, A. J.; EIT Team

2001-07-01

The large dynamic range provided by the SOHO/EIT CCD (1 : 5000) is needed to observe the large EUV zoom of coronal structures from coronal homes up to flares. Histograms show that often a wide dynamic range is present in each image. Extracting hidden structures in the background level requires specific techniques such as the use of the Multiscale Vision Model (MVM, Bijaoui et al., 1998). This method, based on wavelet transformations optimizes detection of various size objects, however complex they may be. Bijaoui et al. built the Multiscale Vision Model to extract small dynamical structures from noise, mainly for studying galaxies. In this paper, we describe requirements for the use of this method with SOHO/EIT images (calibration, size of the image, dynamics of the subimage, etc.). Two different areas were studied revealing hidden structures: (1) classical coronal mass ejection (CME) formation and (2) a complex group of active regions with its evolution. The aim of this paper is to define carefully the constraints for this new method of imaging the solar corona with SOHO/EIT. Physical analysis derived from multi-wavelength observations will later complete these first results.

High dynamic range CMOS-based mammography detector for FFDM and DBT

NASA Astrophysics Data System (ADS)

Peters, Inge M.; Smit, Chiel; Miller, James J.; Lomako, Andrey

2016-03-01

Digital Breast Tomosynthesis (DBT) requires excellent image quality in a dynamic mode at very low dose levels while Full Field Digital Mammography (FFDM) is a static imaging modality that requires high saturation dose levels. These opposing requirements can only be met by a dynamic detector with a high dynamic range. This paper will discuss a wafer-scale CMOS-based mammography detector with 49.5 μm pixels and a CsI scintillator. Excellent image quality is obtained for FFDM as well as DBT applications, comparing favorably with a-Se detectors that dominate the X-ray mammography market today. The typical dynamic range of a mammography detector is not high enough to accommodate both the low noise and the high saturation dose requirements for DBT and FFDM applications, respectively. An approach based on gain switching does not provide the signal-to-noise benefits in the low-dose DBT conditions. The solution to this is to add frame summing functionality to the detector. In one X-ray pulse several image frames will be acquired and summed. The requirements to implement this into a detector are low noise levels, high frame rates and low lag performance, all of which are unique characteristics of CMOS detectors. Results are presented to prove that excellent image quality is achieved, using a single detector for both DBT as well as FFDM dose conditions. This method of frame summing gave the opportunity to optimize the detector noise and saturation level for DBT applications, to achieve high DQE level at low dose, without compromising the FFDM performance.

A THz heterodyne instrument for biomedical imaging applications

NASA Technical Reports Server (NTRS)

Siegel, Peter H.

2004-01-01

An ultra-wide-dynamic-range heterodyne imaging system operating at 2.5 THz is described. The instrument employs room temperature Schottky barrier diode mixers and far infrared gas laser sources developed for NASA space applications. A dynamic range of over 100dB at fixed intermediate frequencies has been realized. Amplitude/phase tracking circuitry results in stability of 0.02 dB and +-2 degrees of phase. The system is being employed to characterize biological (human and animal derived tissues) and a variety of materials of interest to NASA. This talk will describe the instrument and some of the early imaging experiments on everything from mouse tail to aerogel.

Enhancement tuning and control for high dynamic range images in multi-scale locally adaptive contrast enhancement algorithms

NASA Astrophysics Data System (ADS)

Cvetkovic, Sascha D.; Schirris, Johan; de With, Peter H. N.

2009-01-01

For real-time imaging in surveillance applications, visibility of details is of primary importance to ensure customer confidence. If we display High Dynamic-Range (HDR) scenes whose contrast spans four or more orders of magnitude on a conventional monitor without additional processing, results are unacceptable. Compression of the dynamic range is therefore a compulsory part of any high-end video processing chain because standard monitors are inherently Low- Dynamic Range (LDR) devices with maximally two orders of display dynamic range. In real-time camera processing, many complex scenes are improved with local contrast enhancements, bringing details to the best possible visibility. In this paper, we show how a multi-scale high-frequency enhancement scheme, in which gain is a non-linear function of the detail energy, can be used for the dynamic range compression of HDR real-time video camera signals. We also show the connection of our enhancement scheme to the processing way of the Human Visual System (HVS). Our algorithm simultaneously controls perceived sharpness, ringing ("halo") artifacts (contrast) and noise, resulting in a good balance between visibility of details and non-disturbance of artifacts. The overall quality enhancement, suitable for both HDR and LDR scenes, is based on a careful selection of the filter types for the multi-band decomposition and a detailed analysis of the signal per frequency band.

The design and characterization of a digital optical breast cancer imaging system.

PubMed

Flexman, Molly L; Li, Yang; Bur, Andres M; Fong, Christopher J; Masciotti, James M; Al Abdi, Rabah; Barbour, Randall L; Hielscher, Andreas H

2008-01-01

Optical imaging has the potential to play a major role in breast cancer screening and diagnosis due to its ability to image cancer characteristics such as angiogenesis and hypoxia. A promising approach to evaluate and quantify these characteristics is to perform dynamic imaging studies in which one monitors the hemodynamic response to an external stimulus, such as a valsalva maneuver. It has been shown that the response to such stimuli shows MARKED differences between cancerous and healthy tissues. The fast imaging rates and large dynamic range of digital devices makes them ideal for this type of imaging studies. Here we present a digital optical tomography system designed specifically for dynamic breast imaging. The instrument uses laser diodes at 4 different near-infrared wavelengths with 32 sources and 128 silicon photodiode detectors.

A Dynamic Range Enhanced Readout Technique with a Two-Step TDC for High Speed Linear CMOS Image Sensors.

PubMed

Gao, Zhiyuan; Yang, Congjie; Xu, Jiangtao; Nie, Kaiming

2015-11-06

This paper presents a dynamic range (DR) enhanced readout technique with a two-step time-to-digital converter (TDC) for high speed linear CMOS image sensors. A multi-capacitor and self-regulated capacitive trans-impedance amplifier (CTIA) structure is employed to extend the dynamic range. The gain of the CTIA is auto adjusted by switching different capacitors to the integration node asynchronously according to the output voltage. A column-parallel ADC based on a two-step TDC is utilized to improve the conversion rate. The conversion is divided into coarse phase and fine phase. An error calibration scheme is also proposed to correct quantization errors caused by propagation delay skew within -T(clk)~+T(clk). A linear CMOS image sensor pixel array is designed in the 0.13 μm CMOS process to verify this DR-enhanced high speed readout technique. The post simulation results indicate that the dynamic range of readout circuit is 99.02 dB and the ADC achieves 60.22 dB SNDR and 9.71 bit ENOB at a conversion rate of 2 MS/s after calibration, with 14.04 dB and 2.4 bit improvement, compared with SNDR and ENOB of that without calibration.

Adaptive time-sequential binary sensing for high dynamic range imaging

NASA Astrophysics Data System (ADS)

Hu, Chenhui; Lu, Yue M.

2012-06-01

We present a novel image sensor for high dynamic range imaging. The sensor performs an adaptive one-bit quantization at each pixel, with the pixel output switched from 0 to 1 only if the number of photons reaching that pixel is greater than or equal to a quantization threshold. With an oracle knowledge of the incident light intensity, one can pick an optimal threshold (for that light intensity) and the corresponding Fisher information contained in the output sequence follows closely that of an ideal unquantized sensor over a wide range of intensity values. This observation suggests the potential gains one may achieve by adaptively updating the quantization thresholds. As the main contribution of this work, we propose a time-sequential threshold-updating rule that asymptotically approaches the performance of the oracle scheme. With every threshold mapped to a number of ordered states, the dynamics of the proposed scheme can be modeled as a parametric Markov chain. We show that the frequencies of different thresholds converge to a steady-state distribution that is concentrated around the optimal choice. Moreover, numerical experiments show that the theoretical performance measures (Fisher information and Craḿer-Rao bounds) can be achieved by a maximum likelihood estimator, which is guaranteed to find globally optimal solution due to the concavity of the log-likelihood functions. Compared with conventional image sensors and the strategy that utilizes a constant single-photon threshold considered in previous work, the proposed scheme attains orders of magnitude improvement in terms of sensor dynamic ranges.

Automatic image equalization and contrast enhancement using Gaussian mixture modeling.

PubMed

Celik, Turgay; Tjahjadi, Tardi

2012-01-01

In this paper, we propose an adaptive image equalization algorithm that automatically enhances the contrast in an input image. The algorithm uses the Gaussian mixture model to model the image gray-level distribution, and the intersection points of the Gaussian components in the model are used to partition the dynamic range of the image into input gray-level intervals. The contrast equalized image is generated by transforming the pixels' gray levels in each input interval to the appropriate output gray-level interval according to the dominant Gaussian component and the cumulative distribution function of the input interval. To take account of the hypothesis that homogeneous regions in the image represent homogeneous silences (or set of Gaussian components) in the image histogram, the Gaussian components with small variances are weighted with smaller values than the Gaussian components with larger variances, and the gray-level distribution is also used to weight the components in the mapping of the input interval to the output interval. Experimental results show that the proposed algorithm produces better or comparable enhanced images than several state-of-the-art algorithms. Unlike the other algorithms, the proposed algorithm is free of parameter setting for a given dynamic range of the enhanced image and can be applied to a wide range of image types.

High dynamic range adaptive real-time smart camera: an overview of the HDR-ARTiST project

NASA Astrophysics Data System (ADS)

Lapray, Pierre-Jean; Heyrman, Barthélémy; Ginhac, Dominique

2015-04-01

Standard cameras capture only a fraction of the information that is visible to the human visual system. This is specifically true for natural scenes including areas of low and high illumination due to transitions between sunlit and shaded areas. When capturing such a scene, many cameras are unable to store the full Dynamic Range (DR) resulting in low quality video where details are concealed in shadows or washed out by sunlight. The imaging technique that can overcome this problem is called HDR (High Dynamic Range) imaging. This paper describes a complete smart camera built around a standard off-the-shelf LDR (Low Dynamic Range) sensor and a Virtex-6 FPGA board. This smart camera called HDR-ARtiSt (High Dynamic Range Adaptive Real-time Smart camera) is able to produce a real-time HDR live video color stream by recording and combining multiple acquisitions of the same scene while varying the exposure time. This technique appears as one of the most appropriate and cheapest solution to enhance the dynamic range of real-life environments. HDR-ARtiSt embeds real-time multiple captures, HDR processing, data display and transfer of a HDR color video for a full sensor resolution (1280 1024 pixels) at 60 frames per second. The main contributions of this work are: (1) Multiple Exposure Control (MEC) dedicated to the smart image capture with alternating three exposure times that are dynamically evaluated from frame to frame, (2) Multi-streaming Memory Management Unit (MMMU) dedicated to the memory read/write operations of the three parallel video streams, corresponding to the different exposure times, (3) HRD creating by combining the video streams using a specific hardware version of the Devebecs technique, and (4) Global Tone Mapping (GTM) of the HDR scene for display on a standard LCD monitor.

Multiple-viewing-zone integral imaging using a dynamic barrier array for three-dimensional displays.

PubMed

Choi, Heejin; Min, Sung-Wook; Jung, Sungyong; Park, Jae-Hyeung; Lee, Byoungho

2003-04-21

In spite of many advantages of integral imaging, the viewing zone in which an observer can see three-dimensional images is limited within a narrow range. Here, we propose a novel method to increase the number of viewing zones by using a dynamic barrier array. We prove our idea by fabricating and locating the dynamic barrier array between a lens array and a display panel. By tilting the barrier array, it is possible to distribute images for each viewing zone. Thus, the number of viewing zones can be increased with an increment of the states of the barrier array tilt.

New feature of the neutron color image intensifier

NASA Astrophysics Data System (ADS)

Nittoh, Koichi; Konagai, Chikara; Noji, Takashi; Miyabe, Keisuke

2009-06-01

We developed prototype neutron color image intensifiers with high-sensitivity, wide dynamic range and long-life characteristics. In the prototype intensifier (Gd-Type 1), a terbium-activated Gd 2O 2S is used as the input-screen phosphor. In the upgraded model (Gd-Type 2), Gd 2O 3 and CsI:Na are vacuum deposited to form the phosphor layer, which improved the sensitivity and the spatial uniformity. A europium-activated Y 2O 2S multi-color scintillator, emitting red, green and blue photons with different intensities, is utilized as the output screen of the intensifier. By combining this image intensifier with a suitably tuned high-sensitive color CCD camera, higher sensitivity and wider dynamic range could be simultaneously attained than that of the conventional P20-phosphor-type image intensifier. The results of experiments at the JRR-3M neutron radiography irradiation port (flux: 1.5×10 8 n/cm 2/s) showed that these neutron color image intensifiers can clearly image dynamic phenomena with a 30 frame/s video picture. It is expected that the color image intensifier will be used as a new two-dimensional neutron sensor in new application fields.

P04.19 Recommendations for computation of textural measures obtained from 3D brain tumor MRIs: A robustness analysis points out the need for standardization.

PubMed Central

Molina, D.; Pérez-Beteta, J.; Martínez-González, A.; Velásquez, C.; Martino, J.; Luque, B.; Revert, A.; Herruzo, I.; Arana, E.; Pérez-García, V. M.

2017-01-01

Abstract Introduction: Textural analysis refers to a variety of mathematical methods used to quantify the spatial variations in grey levels within images. In brain tumors, textural features have a great potential as imaging biomarkers having been shown to correlate with survival, tumor grade, tumor type, etc. However, these measures should be reproducible under dynamic range and matrix size changes for their clinical use. Our aim is to study this robustness in brain tumors with 3D magnetic resonance imaging, not previously reported in the literature. Materials and methods: 3D T1-weighted images of 20 patients with glioblastoma (64.80 ± 9.12 years-old) obtained from a 3T scanner were analyzed. Tumors were segmented using an in-house semi-automatic 3D procedure. A set of 16 3D textural features of the most common types (co-occurrence and run-length matrices) were selected, providing regional (run-length based measures) and local information (co-ocurrence matrices) on the tumor heterogeneity. Feature robustness was assessed by means of the coefficient of variation (CV) under both dynamic range (16, 32 and 64 gray levels) and/or matrix size (256x256 and 432x432) changes. Results: None of the textural features considered were robust under dynamic range changes. The textural co-occurrence matrix feature Entropy was the only textural feature robust (CV < 10%) under spatial resolution changes. Conclusions: In general, textural measures of three-dimensional brain tumor images are neither robust under dynamic range nor under matrix size changes. Thus, it becomes mandatory to fix standards for image rescaling after acquisition before the textural features are computed if they are to be used as imaging biomarkers. For T1-weighted images a dynamic range of 16 grey levels and a matrix size of 256x256 (and isotropic voxel) is found to provide reliable and comparable results and is feasible with current MRI scanners. The implications of this work go beyond the specific tumor type and MRI sequence studied here and pose the need for standardization in textural feature calculation of oncological images. FUNDING: James S. Mc. Donnell Foundation (USA) 21st Century Science Initiative in Mathematical and Complex Systems Approaches for Brain Cancer [Collaborative award 220020450 and planning grant 220020420], MINECO/FEDER [MTM2015-71200-R], JCCM [PEII-2014-031-P].

The fresnel interferometric imager

NASA Astrophysics Data System (ADS)

Koechlin, Laurent; Serre, Denis; Deba, Paul; Pelló, Roser; Peillon, Christelle; Duchon, Paul; Gomez de Castro, Ana Ines; Karovska, Margarita; Désert, Jean-Michel; Ehrenreich, David; Hebrard, Guillaume; Lecavelier Des Etangs, Alain; Ferlet, Roger; Sing, David; Vidal-Madjar, Alfred

2009-03-01

The Fresnel Interferometric Imager has been proposed to the European Space Agency (ESA) Cosmic Vision plan as a class L mission. This mission addresses several themes of the CV Plan: Exoplanet study, Matter in extreme conditions, and The Universe taking shape. This paper is an abridged version of the original ESA proposal. We have removed most of the technical and financial issues, to concentrate on the instrumental design and astrophysical missions. The instrument proposed is an ultra-lightweight telescope, featuring a novel optical concept based on diffraction focussing. It yields high dynamic range images, while releasing constraints on positioning and manufacturing of the main optical elements. This concept should open the way to very large apertures in space. In this two spacecraft formation-flying instrument, one spacecraft holds the focussing element: the Fresnel interferometric array; the other spacecraft holds the field optics, focal instrumentation, and detectors. The Fresnel array proposed here is a 3.6 ×3.6 m square opaque foil punched with 105 to 106 void “subapertures”. Focusing is achieved with no other optical element: the shape and positioning of the subapertures (holes in the foil) is responsible for beam combining by diffraction, and 5% to 10% of the total incident light ends up into a sharp focus. The consequence of this high number of subapertures is high dynamic range images. In addition, as it uses only a combination of vacuum and opaque material, this focussing method is potentially efficient over a very broad wavelength domain. The focal length of such diffractive focussing devices is wavelength dependent. However, this can be corrected. We have tested optically the efficiency of the chromatism correction on artificial sources (500 < λ < 750 nm): the images are diffraction limited, and the dynamic range measured on an artificial double source reaches 6.2 10 - 6. We have also validated numerical simulation algorithms for larger Fresnel interferometric arrays. These simulations yield a dynamic range (rejection factor) close to 10 - 8 for arrays such as the 3.6 m one we propose. A dynamic range of 10 - 8 allows detection of objects at contrasts as high as than 10 - 9 in most of the field. The astrophysical applications cover many objects in the IR, visible an UV domains. Examples are presented, taking advantage of the high angular resolution and dynamic range capabilities of this concept.

Design of CMOS imaging system based on FPGA

NASA Astrophysics Data System (ADS)

Hu, Bo; Chen, Xiaolai

2017-10-01

In order to meet the needs of engineering applications for high dynamic range CMOS camera under the rolling shutter mode, a complete imaging system is designed based on the CMOS imaging sensor NSC1105. The paper decides CMOS+ADC+FPGA+Camera Link as processing architecture and introduces the design and implementation of the hardware system. As for camera software system, which consists of CMOS timing drive module, image acquisition module and transmission control module, the paper designs in Verilog language and drives it to work properly based on Xilinx FPGA. The ISE 14.6 emulator ISim is used in the simulation of signals. The imaging experimental results show that the system exhibits a 1280*1024 pixel resolution, has a frame frequency of 25 fps and a dynamic range more than 120dB. The imaging quality of the system satisfies the requirement of the index.

An analog gamma correction scheme for high dynamic range CMOS logarithmic image sensors.

PubMed

Cao, Yuan; Pan, Xiaofang; Zhao, Xiaojin; Wu, Huisi

2014-12-15

In this paper, a novel analog gamma correction scheme with a logarithmic image sensor dedicated to minimize the quantization noise of the high dynamic applications is presented. The proposed implementation exploits a non-linear voltage-controlled-oscillator (VCO) based analog-to-digital converter (ADC) to perform the gamma correction during the analog-to-digital conversion. As a result, the quantization noise does not increase while the same high dynamic range of logarithmic image sensor is preserved. Moreover, by combining the gamma correction with the analog-to-digital conversion, the silicon area and overall power consumption can be greatly reduced. The proposed gamma correction scheme is validated by the reported simulation results and the experimental results measured for our designed test structure, which is fabricated with 0.35 μm standard complementary-metal-oxide-semiconductor (CMOS) process.

An Analog Gamma Correction Scheme for High Dynamic Range CMOS Logarithmic Image Sensors

PubMed Central

Cao, Yuan; Pan, Xiaofang; Zhao, Xiaojin; Wu, Huisi

2014-01-01

In this paper, a novel analog gamma correction scheme with a logarithmic image sensor dedicated to minimize the quantization noise of the high dynamic applications is presented. The proposed implementation exploits a non-linear voltage-controlled-oscillator (VCO) based analog-to-digital converter (ADC) to perform the gamma correction during the analog-to-digital conversion. As a result, the quantization noise does not increase while the same high dynamic range of logarithmic image sensor is preserved. Moreover, by combining the gamma correction with the analog-to-digital conversion, the silicon area and overall power consumption can be greatly reduced. The proposed gamma correction scheme is validated by the reported simulation results and the experimental results measured for our designed test structure, which is fabricated with 0.35 μm standard complementary-metal-oxide-semiconductor (CMOS) process. PMID:25517692

Crowdsourcing-based evaluation of privacy in HDR images

NASA Astrophysics Data System (ADS)

Korshunov, Pavel; Nemoto, Hiromi; Skodras, Athanassios; Ebrahimi, Touradj

2014-05-01

The ability of High Dynamic Range imaging (HDRi) to capture details in high-contrast environments, making both dark and bright regions clearly visible, has a strong implication on privacy. However, the extent to which HDRi affects privacy when it is used instead of typical Standard Dynamic Range imaging (SDRi) is not yet clear. In this paper, we investigate the effect of HDRi on privacy via crowdsourcing evaluation using the Microworkers platform. Due to the lack of HDRi standard privacy evaluation dataset, we have created such dataset containing people of varying gender, race, and age, shot indoor and outdoor and under large range of lighting conditions. We evaluate the tone-mapped versions of these images, obtained by several representative tone-mapping algorithms, using subjective privacy evaluation methodology. Evaluation was performed using crowdsourcing-based framework, because it is a popular and effective alternative to traditional lab-based assessment. The results of the experiments demonstrate a significant loss of privacy when even tone-mapped versions of HDR images are used compared to typical SDR images shot with a standard exposure.

An improved contrast enhancement algorithm for infrared images based on adaptive double plateaus histogram equalization

NASA Astrophysics Data System (ADS)

Li, Shuo; Jin, Weiqi; Li, Li; Li, Yiyang

2018-05-01

Infrared thermal images can reflect the thermal-radiation distribution of a particular scene. However, the contrast of the infrared images is usually low. Hence, it is generally necessary to enhance the contrast of infrared images in advance to facilitate subsequent recognition and analysis. Based on the adaptive double plateaus histogram equalization, this paper presents an improved contrast enhancement algorithm for infrared thermal images. In the proposed algorithm, the normalized coefficient of variation of the histogram, which characterizes the level of contrast enhancement, is introduced as feedback information to adjust the upper and lower plateau thresholds. The experiments on actual infrared images show that compared to the three typical contrast-enhancement algorithms, the proposed algorithm has better scene adaptability and yields better contrast-enhancement results for infrared images with more dark areas or a higher dynamic range. Hence, it has high application value in contrast enhancement, dynamic range compression, and digital detail enhancement for infrared thermal images.

Extended dynamic range of Doppler OCT by application of a new method to high density B-scans using a MHz FDML swept laser source (Conference Presentation)

NASA Astrophysics Data System (ADS)

Elahi, Sahar; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.

2017-02-01

The limited dynamic range of optical coherence tomography (OCT) Doppler velocity measurements makes it difficult to conduct experiments on samples requiring a large dynamic range without phase wrapping at high velocities or loss of sensitivity at slow velocities. Hemodynamics and wall motion undergo significant increases in velocity as the embryonic heart develops. Experimental studies indicate that altered hemodynamics in early-stage embryonic hearts can lead to congenital heart diseases (CHDs), motivating close monitoring of blood flow over several stages of development. We have built a high-speed OCT system using an FDML laser (Optores GmbH, Germany) at a sweep rate of 1.68 MHz (axial resolution - 12 μm, sensitivity - 105 dB, phase stability - 17 mrad). The speed of this OCT system allows us to acquire high-density B-scans to obtain an extended velocity dynamic range without sacrificing the frame rate (100 Hz). The extended dynamic range within a frame is achieved by varying the A-scan interval at which the phase difference is found, enabling detection of velocities ranging from tens of microns per second to hundreds of millimeters per second. The extra lines in a frame can also be utilized to improve the structural and Doppler images via complex averaging. In structural images where the presence of blood causes additional scattering, complex averaging helps retrieve features located deeper in the tissue. Moreover, high-density frames can be registered to 4D volumes to determine the orthogonal direction of flow for calculating shear stress as well as estimating the cardiac output. In conclusion, high density B-scans acquired by our high-speed OCT system enable image enhancement and direct measurement of biological parameters in cohort studies.

An HDR imaging method with DTDI technology for push-broom cameras

NASA Astrophysics Data System (ADS)

Sun, Wu; Han, Chengshan; Xue, Xucheng; Lv, Hengyi; Shi, Junxia; Hu, Changhong; Li, Xiangzhi; Fu, Yao; Jiang, Xiaonan; Huang, Liang; Han, Hongyin

2018-03-01

Conventionally, high dynamic-range (HDR) imaging is based on taking two or more pictures of the same scene with different exposure. However, due to a high-speed relative motion between the camera and the scene, it is hard for this technique to be applied to push-broom remote sensing cameras. For the sake of HDR imaging in push-broom remote sensing applications, the present paper proposes an innovative method which can generate HDR images without redundant image sensors or optical components. Specifically, this paper adopts an area array CMOS (complementary metal oxide semiconductor) with the digital domain time-delay-integration (DTDI) technology for imaging, instead of adopting more than one row of image sensors, thereby taking more than one picture with different exposure. And then a new HDR image by fusing two original images with a simple algorithm can be achieved. By conducting the experiment, the dynamic range (DR) of the image increases by 26.02 dB. The proposed method is proved to be effective and has potential in other imaging applications where there is a relative motion between the cameras and scenes.

The superiority of L3-CCDs in the high-flux and wide dynamic range regimes

NASA Astrophysics Data System (ADS)

Butler, Raymond F.; Sheehan, Brendan J.

2008-02-01

Low Light Level CCD (L3-CCD) cameras have received much attention for high cadence astronomical imaging applications. Efforts to date have concentrated on exploiting them for two scenarios: post-exposure image sharpening and ``lucky imaging'', and rapid variability in astrophysically interesting sources. We demonstrate their marked superiority in a third distinct scenario: observing in the high-flux and wide dynamic range regimes. We realized that the unique features of L3-CCDs would make them ideal for maximizing signal-to-noise in observations of bright objects (whether variable or not), and for high dynamic range scenarios such as faint targets embedded in a crowded field of bright objects. Conventional CCDs have drawbacks in such regimes, due to a poor duty cycle-the combination of short exposure times (for time-series sampling or to avoid saturation) and extended readout times (for minimizing readout noise). For different telescope sizes, we use detailed models to show that a range of conventional imaging systems are photometrically out-performed across a wide range of object brightness, once the operational parameters of the L3-CCD are carefully set. The cross-over fluxes, above which the L3-CCD is operationally superior, are surprisingly faint-even for modest telescope apertures. We also show that the use of L3-CCDs is the optimum strategy for minimizing atmospheric scintillation noise in photometric observations employing a given telescope aperture. This is particularly significant, since scintillation can be the largest source of error in timeseries photometry. These results should prompt a new direction in developing imaging instrumentation solutions for observatories.

An improved method to estimate reflectance parameters for high dynamic range imaging

NASA Astrophysics Data System (ADS)

Li, Shiying; Deguchi, Koichiro; Li, Renfa; Manabe, Yoshitsugu; Chihara, Kunihiro

2008-01-01

Two methods are described to accurately estimate diffuse and specular reflectance parameters for colors, gloss intensity and surface roughness, over the dynamic range of the camera used to capture input images. Neither method needs to segment color areas on an image, or to reconstruct a high dynamic range (HDR) image. The second method improves on the first, bypassing the requirement for specific separation of diffuse and specular reflection components. For the latter method, diffuse and specular reflectance parameters are estimated separately, using the least squares method. Reflection values are initially assumed to be diffuse-only reflection components, and are subjected to the least squares method to estimate diffuse reflectance parameters. Specular reflection components, obtained by subtracting the computed diffuse reflection components from reflection values, are then subjected to a logarithmically transformed equation of the Torrance-Sparrow reflection model, and specular reflectance parameters for gloss intensity and surface roughness are finally estimated using the least squares method. Experiments were carried out using both methods, with simulation data at different saturation levels, generated according to the Lambert and Torrance-Sparrow reflection models, and the second method, with spectral images captured by an imaging spectrograph and a moving light source. Our results show that the second method can estimate the diffuse and specular reflectance parameters for colors, gloss intensity and surface roughness more accurately and faster than the first one, so that colors and gloss can be reproduced more efficiently for HDR imaging.

High Dynamic Range Digital Imaging of Spacecraft

NASA Technical Reports Server (NTRS)

Karr, Brian A.; Chalmers, Alan; Debattista, Kurt

2014-01-01

The ability to capture engineering imagery with a wide degree of dynamic range during rocket launches is critical for post launch processing and analysis [USC03, NNC86]. Rocket launches often present an extreme range of lightness, particularly during night launches. Night launches present a two-fold problem: capturing detail of the vehicle and scene that is masked by darkness, while also capturing detail in the engine plume.

Guided filter-based fusion method for multiexposure images

NASA Astrophysics Data System (ADS)

Hou, Xinglin; Luo, Haibo; Qi, Feng; Zhou, Peipei

2016-11-01

It is challenging to capture a high-dynamic range (HDR) scene using a low-dynamic range camera. A weighted sum-based image fusion (IF) algorithm is proposed so as to express an HDR scene with a high-quality image. This method mainly includes three parts. First, two image features, i.e., gradients and well-exposedness are measured to estimate the initial weight maps. Second, the initial weight maps are refined by a guided filter, in which the source image is considered as the guidance image. This process could reduce the noise in initial weight maps and preserve more texture consistent with the original images. Finally, the fused image is constructed by a weighted sum of source images in the spatial domain. The main contributions of this method are the estimation of the initial weight maps and the appropriate use of the guided filter-based weight maps refinement. It provides accurate weight maps for IF. Compared to traditional IF methods, this algorithm avoids image segmentation, combination, and the camera response curve calibration. Furthermore, experimental results demonstrate the superiority of the proposed method in both subjective and objective evaluations.

High dynamic range algorithm based on HSI color space

NASA Astrophysics Data System (ADS)

Zhang, Jiancheng; Liu, Xiaohua; Dong, Liquan; Zhao, Yuejin; Liu, Ming

2014-10-01

This paper presents a High Dynamic Range algorithm based on HSI color space. To keep hue and saturation of original image and conform to human eye vision effect is the first problem, convert the input image data to HSI color space which include intensity dimensionality. To raise the speed of the algorithm is the second problem, use integral image figure out the average of every pixel intensity value under a certain scale, as local intensity component of the image, and figure out detail intensity component. To adjust the overall image intensity is the third problem, we can get an S type curve according to the original image information, adjust the local intensity component according to the S type curve. To enhance detail information is the fourth problem, adjust the detail intensity component according to the curve designed in advance. The weighted sum of local intensity component after adjusted and detail intensity component after adjusted is final intensity. Converting synthetic intensity and other two dimensionality to output color space can get final processed image.

Dynamic contrast-enhanced MRA at 1.5 T for detection of arteriovenous shunting before and after Onyx embolization of cerebral arteriovenous malformations.

PubMed

Nogueira, Raul G; Bayrlee, Ahmad; Hirsch, Joshua A; Yoo, Albert J; Copen, William A

2013-10-01

Conventional non-invasive angiographic techniques for evaluating cerebral Arteriovenous Malformations (cAVMs) after embolization treatment are limited by their inability to acquire time-resolved images. We describe the use of dynamic contrast-enhanced magnetic resonance angiography (MRA) in the evaluation of residual arteriovenous shunting in cAVMs following Onyx embolization. Six subjects who underwent multimodal MR imaging including dynamic MRA after different stages of endovascular treatment with Onyx were included. Each MRA was assessed for the presence of residual arteriovenous shunting. The results were compared with digital subtraction angiography (DSA). Mean age was 41 years (range, 25-63) and the mean maximum AVM diameter was 5.3 cm (range, 4.7-6.0). Fourteen dynamic MRA were performed using a 1.5 T scanner. Arteriovenous shunting was detected in thirteen of fourteen patients by both dynamic MRA and DSA, with complete agreement between the two techniques. The only MRA without detectable residual arteriovenous shunting was for a subject who had complete treatment with no residual cAVM as confirmed by the DSA images. Dynamic contrast-enhanced MRA is a promising non-invasive modality in identifying residual arteriovenous shunting after different stages of AVM embolization, achieving 100% agreement in this small study. Embolization with Onyx caused no significant image artifact. Copyright © 2013 by the American Society of Neuroimaging.

High order magnetic optics for high dynamic range proton radiography at a kinetic energy of 800 MeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sjue, S. K. L., E-mail: sjue@lanl.gov; Mariam, F. G.; Merrill, F. E.

2016-01-15

Flash radiography with 800 MeV kinetic energy protons at Los Alamos National Laboratory is an important experimental tool for investigations of dynamic material behavior driven by high explosives or pulsed power. The extraction of quantitative information about density fields in a dynamic experiment from proton generated images requires a high fidelity model of the proton imaging process. It is shown that accurate calculations of the transmission through the magnetic lens system require terms beyond second order for protons far from the tune energy. The approach used integrates the correlated multiple Coulomb scattering distribution simultaneously over the collimator and the imagemore » plane. Comparison with a series of static calibration images demonstrates the model’s accurate reproduction of both the transmission and blur over a wide range of tune energies in an inverse identity lens that consists of four quadrupole electromagnets.« less

Blurred Star Image Processing for Star Sensors under Dynamic Conditions

PubMed Central

Zhang, Weina; Quan, Wei; Guo, Lei

2012-01-01

The precision of star point location is significant to identify the star map and to acquire the aircraft attitude for star sensors. Under dynamic conditions, star images are not only corrupted by various noises, but also blurred due to the angular rate of the star sensor. According to different angular rates under dynamic conditions, a novel method is proposed in this article, which includes a denoising method based on adaptive wavelet threshold and a restoration method based on the large angular rate. The adaptive threshold is adopted for denoising the star image when the angular rate is in the dynamic range. Then, the mathematical model of motion blur is deduced so as to restore the blurred star map due to large angular rate. Simulation results validate the effectiveness of the proposed method, which is suitable for blurred star image processing and practical for attitude determination of satellites under dynamic conditions. PMID:22778666

Single-frequency 3D synthetic aperture imaging with dynamic metasurface antennas.

PubMed

Boyarsky, Michael; Sleasman, Timothy; Pulido-Mancera, Laura; Diebold, Aaron V; Imani, Mohammadreza F; Smith, David R

2018-05-20

Through aperture synthesis, an electrically small antenna can be used to form a high-resolution imaging system capable of reconstructing three-dimensional (3D) scenes. However, the large spectral bandwidth typically required in synthetic aperture radar systems to resolve objects in range often requires costly and complex RF components. We present here an alternative approach based on a hybrid imaging system that combines a dynamically reconfigurable aperture with synthetic aperture techniques, demonstrating the capability to resolve objects in three dimensions (3D), with measurements taken at a single frequency. At the core of our imaging system are two metasurface apertures, both of which consist of a linear array of metamaterial irises that couple to a common waveguide feed. Each metamaterial iris has integrated within it a diode that can be biased so as to switch the element on (radiating) or off (non-radiating), such that the metasurface antenna can produce distinct radiation profiles corresponding to different on/off patterns of the metamaterial element array. The electrically large size of the metasurface apertures enables resolution in range and one cross-range dimension, while aperture synthesis provides resolution in the other cross-range dimension. The demonstrated imaging capabilities of this system represent a step forward in the development of low-cost, high-performance 3D microwave imaging systems.

A Rotatable Quality Control Phantom for Evaluating the Performance of Flat Panel Detectors in Imaging Moving Objects.

PubMed

Haga, Yoshihiro; Chida, Koichi; Inaba, Yohei; Kaga, Yuji; Meguro, Taiichiro; Zuguchi, Masayuki

2016-02-01

As the use of diagnostic X-ray equipment with flat panel detectors (FPDs) has increased, so has the importance of proper management of FPD systems. To ensure quality control (QC) of FPD system, an easy method for evaluating FPD imaging performance for both stationary and moving objects is required. Until now, simple rotatable QC phantoms have not been available for the easy evaluation of the performance (spatial resolution and dynamic range) of FPD in imaging moving objects. We developed a QC phantom for this purpose. It consists of three thicknesses of copper and a rotatable test pattern of piano wires of various diameters. Initial tests confirmed its stable performance. Our moving phantom is very useful for QC of FPD images of moving objects because it enables visual evaluation of image performance (spatial resolution and dynamic range) easily.

High dynamic range pixel architecture for advanced diagnostic medical x-ray imaging applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Izadi, Mohammad Hadi; Karim, Karim S.

2006-05-15

The most widely used architecture in large-area amorphous silicon (a-Si) flat panel imagers is a passive pixel sensor (PPS), which consists of a detector and a readout switch. While the PPS has the advantage of being compact and amenable toward high-resolution imaging, small PPS output signals are swamped by external column charge amplifier and data line thermal noise, which reduce the minimum readable sensor input signal. In contrast to PPS circuits, on-pixel amplifiers in a-Si technology reduce readout noise to levels that can meet even the stringent requirements for low noise digital x-ray fluoroscopy (<1000 noise electrons). However, larger voltagesmore » at the pixel input cause the output of the amplified pixel to become nonlinear thus reducing the dynamic range. We reported a hybrid amplified pixel architecture based on a combination of PPS and amplified pixel designs that, in addition to low noise performance, also resulted in large-signal linearity and consequently higher dynamic range [K. S. Karim et al., Proc. SPIE 5368, 657 (2004)]. The additional benefit in large-signal linearity, however, came at the cost of an additional pixel transistor. We present an amplified pixel design that achieves the goals of low noise performance and large-signal linearity without the need for an additional pixel transistor. Theoretical calculations and simulation results for noise indicate the applicability of the amplified a-Si pixel architecture for high dynamic range, medical x-ray imaging applications that require switching between low exposure, real-time fluoroscopy and high-exposure radiography.« less

Objective quality assessment of tone-mapped images.

PubMed

Yeganeh, Hojatollah; Wang, Zhou

2013-02-01

Tone-mapping operators (TMOs) that convert high dynamic range (HDR) to low dynamic range (LDR) images provide practically useful tools for the visualization of HDR images on standard LDR displays. Different TMOs create different tone-mapped images, and a natural question is which one has the best quality. Without an appropriate quality measure, different TMOs cannot be compared, and further improvement is directionless. Subjective rating may be a reliable evaluation method, but it is expensive and time consuming, and more importantly, is difficult to be embedded into optimization frameworks. Here we propose an objective quality assessment algorithm for tone-mapped images by combining: 1) a multiscale signal fidelity measure on the basis of a modified structural similarity index and 2) a naturalness measure on the basis of intensity statistics of natural images. Validations using independent subject-rated image databases show good correlations between subjective ranking score and the proposed tone-mapped image quality index (TMQI). Furthermore, we demonstrate the extended applications of TMQI using two examples-parameter tuning for TMOs and adaptive fusion of multiple tone-mapped images.

Radiometric infrared focal plane array imaging system for thermographic applications

NASA Technical Reports Server (NTRS)

Esposito, B. J.; Mccafferty, N.; Brown, R.; Tower, J. R.; Kosonocky, W. F.

1992-01-01

This document describes research performed under the Radiometric Infrared Focal Plane Array Imaging System for Thermographic Applications contract. This research investigated the feasibility of using platinum silicide (PtSi) Schottky-barrier infrared focal plane arrays (IR FPAs) for NASA Langley's specific radiometric thermal imaging requirements. The initial goal of this design was to develop a high spatial resolution radiometer with an NETD of 1 percent of the temperature reading over the range of 0 to 250 C. The proposed camera design developed during this study and described in this report provides: (1) high spatial resolution (full-TV resolution); (2) high thermal dynamic range (0 to 250 C); (3) the ability to image rapid, large thermal transients utilizing electronic exposure control (commandable dynamic range of 2,500,000:1 with exposure control latency of 33 ms); (4) high uniformity (0.5 percent nonuniformity after correction); and (5) high thermal resolution (0.1 C at 25 C background and 0.5 C at 250 C background).

Radiometric infrared focal plane array imaging system for thermographic applications

NASA Astrophysics Data System (ADS)

Esposito, B. J.; McCafferty, N.; Brown, R.; Tower, J. R.; Kosonocky, W. F.

1992-11-01

This document describes research performed under the Radiometric Infrared Focal Plane Array Imaging System for Thermographic Applications contract. This research investigated the feasibility of using platinum silicide (PtSi) Schottky-barrier infrared focal plane arrays (IR FPAs) for NASA Langley's specific radiometric thermal imaging requirements. The initial goal of this design was to develop a high spatial resolution radiometer with an NETD of 1 percent of the temperature reading over the range of 0 to 250 C. The proposed camera design developed during this study and described in this report provides: (1) high spatial resolution (full-TV resolution); (2) high thermal dynamic range (0 to 250 C); (3) the ability to image rapid, large thermal transients utilizing electronic exposure control (commandable dynamic range of 2,500,000:1 with exposure control latency of 33 ms); (4) high uniformity (0.5 percent nonuniformity after correction); and (5) high thermal resolution (0.1 C at 25 C background and 0.5 C at 250 C background).

ISSLS PRIZE IN BIOENGINEERING SCIENCE 2018: dynamic imaging of degenerative spondylolisthesis reveals mid-range dynamic lumbar instability not evident on static clinical radiographs.

PubMed

Dombrowski, Malcolm E; Rynearson, Bryan; LeVasseur, Clarissa; Adgate, Zach; Donaldson, William F; Lee, Joon Y; Aiyangar, Ameet; Anderst, William J

2018-04-01

Degenerative spondylolisthesis (DS) in the setting of symptomatic lumbar spinal stenosis is commonly treated with spinal fusion in addition to decompression with laminectomy. However, recent studies have shown similar clinical outcomes after decompression alone, suggesting that a subset of DS patients may not require spinal fusion. Identification of dynamic instability could prove useful for predicting which patients are at higher risk of post-laminectomy destabilization necessitating fusion. The goal of this study was to determine if static clinical radiographs adequately characterize dynamic instability in patients with lumbar degenerative spondylolisthesis (DS) and to compare the rotational and translational kinematics in vivo during continuous dynamic flexion activity in DS versus asymptomatic age-matched controls. Seven patients with symptomatic single level lumbar DS (6 M, 1 F; 66 ± 5.0 years) and seven age-matched asymptomatic controls (5 M, 2 F age 63.9 ± 6.4 years) underwent biplane radiographic imaging during continuous torso flexion. A volumetric model-based tracking system was used to track each vertebra in the radiographic images using subject-specific 3D bone models from high-resolution computed tomography (CT). In vivo continuous dynamic sagittal rotation (flexion/extension) and AP translation (slip) were calculated and compared to clinical measures of intervertebral flexion/extension and AP translation obtained from standard lateral flexion/extension radiographs. Static clinical radiographs underestimate the degree of AP translation seen on dynamic in vivo imaging (1.0 vs 3.1 mm; p = 0.03). DS patients demonstrated three primary motion patterns compared to a single kinematic pattern in asymptomatic controls when analyzing continuous dynamic in vivo imaging. 3/7 (42%) of patients with DS demonstrated aberrant mid-range motion. Continuous in vivo dynamic imaging in DS reveals a spectrum of aberrant motion with significantly greater kinematic heterogeneity than previously realized that is not readily seen on current clinical imaging. Level V data These slides can be retrieved under Electronic Supplementary Material.

The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket, first flight

NASA Astrophysics Data System (ADS)

Christe, Steven; Glesener, L.; Ishikawa, S.; Ramsey, B.; Takahashi, T.; Watanabe, S.; Saito, S.; Lin, R. P.; Krucker, S.

2013-07-01

Understanding electron acceleration in solar flares requires X-ray studies with greater sensitivity and dynamic range than are available with current solar hard X-ray observers (i.e. the RHESSI spacecraft). RHESSI employs an indirect Fourier imaging method that is intrinsically limited in dynamic range and therefore can rarely image faint coronal flare sources in the presence of bright footpoints. With greater sensitivity and dynamic range, electron acceleration sites in the corona could be studied in great detail. Both these capabilities can be advanced by the use of direct focusing optics. The recently flown Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload demonstrates the feasibility and usefulness of hard X-ray focusing optics for observations of solar hard X-rays. FOXSI features grazing-incidence replicated nickel optics made by the NASA Marshall Space Flight Center and fine-pitch silicon strip detectors developed by the Astro-H team at JAXA/ISAS. FOXSI flew successfully on November 2, 2012, producing images and spectra of a microflare and performing a search for nonthermal emission (4-15 keV) from nanoflares in the quiet Sun. Nanoflares are a candidate for providing the required energy to heat the solar corona to its high temperature of a few million degrees. A future satellite version of FOXSI, featuring similar optics and detectors, could make detailed observations of hard X-rays from flare-accelerated electrons, identifying and characterizing particle acceleration sites and mapping out paths of energetic electrons as they leave these sites and propagate throughout the solar corona.Abstract (2,250 Maximum Characters): Understanding electron acceleration in solar flares requires X-ray studies with greater sensitivity and dynamic range than are available with current solar hard X-ray observers (i.e. the RHESSI spacecraft). RHESSI employs an indirect Fourier imaging method that is intrinsically limited in dynamic range and therefore can rarely image faint coronal flare sources in the presence of bright footpoints. With greater sensitivity and dynamic range, electron acceleration sites in the corona could be studied in great detail. Both these capabilities can be advanced by the use of direct focusing optics. The recently flown Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload demonstrates the feasibility and usefulness of hard X-ray focusing optics for observations of solar hard X-rays. FOXSI features grazing-incidence replicated nickel optics made by the NASA Marshall Space Flight Center and fine-pitch silicon strip detectors developed by the Astro-H team at JAXA/ISAS. FOXSI flew successfully on November 2, 2012, producing images and spectra of a microflare and performing a search for nonthermal emission (4-15 keV) from nanoflares in the quiet Sun. Nanoflares are a candidate for providing the required energy to heat the solar corona to its high temperature of a few million degrees. A future satellite version of FOXSI, featuring similar optics and detectors, could make detailed observations of hard X-rays from flare-accelerated electrons, identifying and characterizing particle acceleration sites and mapping out paths of energetic electrons as they leave these sites and propagate throughout the solar corona.

Performance comparison between 8 and 14 bit-depth imaging in polarization-sensitive swept-source optical coherence tomography

NASA Astrophysics Data System (ADS)

Lu, Zenghai; Kasaragoda, Deepa K.; Matcher, Stephen J.

2011-03-01

We compare true 8 and 14 bit-depth imaging of SS-OCT and polarization-sensitive SS-OCT (PS-SS-OCT) at 1.3μm wavelength by using two hardware-synchronized high-speed data acquisition (DAQ) boards. The two DAQ boards read exactly the same imaging data for comparison. The measured system sensitivity at 8-bit depth is comparable to that for 14-bit acquisition when using the more sensitive of the available full analog input voltage ranges of the ADC. Ex-vivo structural and birefringence images of an equine tendon sample indicate no significant differences between images acquired by the two DAQ boards suggesting that 8-bit DAQ boards can be employed to increase imaging speeds and reduce storage in clinical SS-OCT/PS-SS-OCT systems. We also compare the resulting image quality when the image data sampled with the 14-bit DAQ from human finger skin is artificially bit-reduced during post-processing. However, in agreement with the results reported previously, we also observe that in our system that real-world 8-bit image shows more artifacts than the image acquired by numerically truncating to 8-bits from the raw 14-bit image data, especially in low intensity image area. This is due to the higher noise floor and reduced dynamic range of the 8-bit DAQ. One possible disadvantage is a reduced imaging dynamic range which can manifest itself as an increase in image artefacts due to strong Fresnel reflection.

Multiscale X-ray and Proton Imaging of Bismuth-Tin Solidification

NASA Astrophysics Data System (ADS)

Gibbs, P. J.; Imhoff, S. D.; Morris, C. L.; Merrill, F. E.; Wilde, C. H.; Nedrow, P.; Mariam, F. G.; Fezzaa, K.; Lee, W.-K.; Clarke, A. J.

2014-08-01

The formation of structural patterns during metallic solidification is complex and multiscale in nature, ranging from the nanometer scale, where solid-liquid interface properties are important, to the macroscale, where casting mold filling and intended heat transfer are crucial. X-ray and proton imaging can directly interrogate structure, solute, and fluid flow development in metals from the microscale to the macroscale. X-rays permit high spatio-temporal resolution imaging of microscopic solidification dynamics in thin metal sections. Similarly, high-energy protons permit imaging of mesoscopic and macroscopic solidification dynamics in large sample volumes. In this article, we highlight multiscale x-ray and proton imaging of bismuth-tin alloy solidification to illustrate dynamic measurement of crystal growth rates and solute segregation profiles that can be that can be acquired using these techniques.

Is there a preference for linearity when viewing natural images?

NASA Astrophysics Data System (ADS)

Kane, David; Bertamío, Marcelo

2015-01-01

The system gamma of the imaging pipeline, defined as the product of the encoding and decoding gammas, is typically greater than one and is stronger for images viewed with a dark background (e.g. cinema) than those viewed in lighter conditions (e.g. office displays).1-3 However, for high dynamic range (HDR) images reproduced on a low dynamic range (LDR) monitor, subjects often prefer a system gamma of less than one,4 presumably reflecting the greater need for histogram equalization in HDR images. In this study we ask subjects to rate the perceived quality of images presented on a LDR monitor using various levels of system gamma. We reveal that the optimal system gamma is below one for images with a HDR and approaches or exceeds one for images with a LDR. Additionally, the highest quality scores occur for images where a system gamma of one is optimal, suggesting a preference for linearity (where possible). We find that subjective image quality scores can be predicted by computing the degree of histogram equalization of the lightness distribution. Accordingly, an optimal, image dependent system gamma can be computed that maximizes perceived image quality.

Wide-Field Imaging Using Nitrogen Vacancies

NASA Technical Reports Server (NTRS)

Englund, Dirk Robert (Inventor); Trusheim, Matthew Edwin (Inventor)

2017-01-01

Nitrogen vacancies in bulk diamonds and nanodiamonds can be used to sense temperature, pressure, electromagnetic fields, and pH. Unfortunately, conventional sensing techniques use gated detection and confocal imaging, limiting the measurement sensitivity and precluding wide-field imaging. Conversely, the present sensing techniques do not require gated detection or confocal imaging and can therefore be used to image temperature, pressure, electromagnetic fields, and pH over wide fields of view. In some cases, wide-field imaging supports spatial localization of the NVs to precisions at or below the diffraction limit. Moreover, the measurement range can extend over extremely wide dynamic range at very high sensitivity.

Computational fluid dynamics analysis of a maglev centrifugal left ventricular assist device.

PubMed

Burgreen, Greg W; Loree, Howard M; Bourque, Kevin; Dague, Charles; Poirier, Victor L; Farrar, David; Hampton, Edward; Wu, Z Jon; Gempp, Thomas M; Schöb, Reto

2004-10-01

The fluid dynamics of the Thoratec HeartMate III (Thoratec Corp., Pleasanton, CA, U.S.A.) left ventricular assist device are analyzed over a range of physiological operating conditions. The HeartMate III is a centrifugal flow pump with a magnetically suspended rotor. The complete pump was analyzed using computational fluid dynamics (CFD) analysis and experimental particle imaging flow visualization (PIFV). A comparison of CFD predictions to experimental imaging shows good agreement. Both CFD and experimental PIFV confirmed well-behaved flow fields in the main components of the HeartMate III pump: inlet, volute, and outlet. The HeartMate III is shown to exhibit clean flow features and good surface washing across its entire operating range.

Ultrahigh-definition dynamic 3D holographic display by active control of volume speckle fields

NASA Astrophysics Data System (ADS)

Yu, Hyeonseung; Lee, Kyeoreh; Park, Jongchan; Park, Yongkeun

2017-01-01

Holographic displays generate realistic 3D images that can be viewed without the need for any visual aids. They operate by generating carefully tailored light fields that replicate how humans see an actual environment. However, the realization of high-performance, dynamic 3D holographic displays has been hindered by the capabilities of present wavefront modulator technology. In particular, spatial light modulators have a small diffraction angle range and limited pixel number limiting the viewing angle and image size of a holographic 3D display. Here, we present an alternative method to generate dynamic 3D images by controlling volume speckle fields significantly enhancing image definition. We use this approach to demonstrate a dynamic display of micrometre-sized optical foci in a volume of 8 mm × 8 mm × 20 mm.

Optimization of CMOS image sensor utilizing variable temporal multisampling partial transfer technique to achieve full-frame high dynamic range with superior low light and stop motion capability

NASA Astrophysics Data System (ADS)

Kabir, Salman; Smith, Craig; Armstrong, Frank; Barnard, Gerrit; Schneider, Alex; Guidash, Michael; Vogelsang, Thomas; Endsley, Jay

2018-03-01

Differential binary pixel technology is a threshold-based timing, readout, and image reconstruction method that utilizes the subframe partial charge transfer technique in a standard four-transistor (4T) pixel CMOS image sensor to achieve a high dynamic range video with stop motion. This technology improves low light signal-to-noise ratio (SNR) by up to 21 dB. The method is verified in silicon using a Taiwan Semiconductor Manufacturing Company's 65 nm 1.1 μm pixel technology 1 megapixel test chip array and is compared with a traditional 4 × oversampling technique using full charge transfer to show low light SNR superiority of the presented technology.

Tone mapping infrared images using conditional filtering-based multi-scale retinex

NASA Astrophysics Data System (ADS)

Luo, Haibo; Xu, Lingyun; Hui, Bin; Chang, Zheng

2015-10-01

Tone mapping can be used to compress the dynamic range of the image data such that it can be fitted within the range of the reproduction media and human vision. The original infrared images that captured with infrared focal plane arrays (IFPA) are high dynamic images, so tone mapping infrared images is an important component in the infrared imaging systems, and it has become an active topic in recent years. In this paper, we present a tone mapping framework using multi-scale retinex. Firstly, a Conditional Gaussian Filter (CGF) was designed to suppress "halo" effect. Secondly, original infrared image is decomposed into a set of images that represent the mean of the image at different spatial resolutions by applying CGF of different scale. And then, a set of images that represent the multi-scale details of original image is produced by dividing the original image pointwise by the decomposed image. Thirdly, the final detail image is reconstructed by weighted sum of the multi-scale detail images together. Finally, histogram scaling and clipping is adopted to remove outliers and scale the detail image, 0.1% of the pixels are clipped at both extremities of the histogram. Experimental results show that the proposed algorithm efficiently increases the local contrast while preventing "halo" effect and provides a good rendition of visual effect.

USAKA Long Range Planning Study

DTIC Science & Technology

1990-03-01

effects. Thus, the additional metric potential of RV imaging is not being realized. 3.3.2 Location Determination The location determination function...deceleration), and radiometric measurements allowing determination of object thermal dynamics and modulation by e.g., tumbling. Key issues involved in these... imaging mode, which is based on ISAR principles, allows determination of object structure and free-body and reentry dynamics, while the metric mode again

Color line scan camera technology and machine vision: requirements to consider

NASA Astrophysics Data System (ADS)

Paernaenen, Pekka H. T.

1997-08-01

Color machine vision has shown a dynamic uptrend in use within the past few years as the introduction of new cameras and scanner technologies itself underscores. In the future, the movement from monochrome imaging to color will hasten, as machine vision system users demand more knowledge about their product stream. As color has come to the machine vision, certain requirements for the equipment used to digitize color images are needed. Color machine vision needs not only a good color separation but also a high dynamic range and a good linear response from the camera used. Good dynamic range and linear response is necessary for color machine vision. The importance of these features becomes even more important when the image is converted to another color space. There is always lost some information when converting integer data to another form. Traditionally the color image processing has been much slower technique than the gray level image processing due to the three times greater data amount per image. The same has applied for the three times more memory needed. The advancements in computers, memory and processing units has made it possible to handle even large color images today cost efficiently. In some cases he image analysis in color images can in fact even be easier and faster than with a similar gray level image because of more information per pixel. Color machine vision sets new requirements for lighting, too. High intensity and white color light is required in order to acquire good images for further image processing or analysis. New development in lighting technology is bringing eventually solutions for color imaging.

Effect of hindpaw electrical stimulation on capillary flow heterogeneity and oxygen delivery (Conference Presentation)

NASA Astrophysics Data System (ADS)

Li, Yuandong; Wei, Wei; Li, Chenxi; Wang, Ruikang K.

2017-02-01

We report a novel use of optical coherence tomography (OCT) based angiography to visualize and quantify dynamic response of cerebral capillary flow pattern in mice upon hindpaw electrical stimulation through the measurement of the capillary transit-time heterogeneity (CTH) and capillary mean transit time (MTT) in a wide dynamic range of a great number of vessels in vivo. The OCT system was developed to have a central wavelength of 1310 nm, a spatial resolution of 8 µm and a system dynamic range of 105 dB at an imaging rate of 92 kHz. The mapping of dynamic cerebral microcirculations was enabled by optical microangiography protocol. From the imaging results, the spatial homogenization of capillary velocity (decreased CTH) was observed in the region of interest (ROI) corresponding to the stimulation, along with an increase in the MTT in the ROI to maintain sufficient oxygen exchange within the brain tissue during functional activation. We validated the oxygen consumption due to an increase of the MTT through demonstrating an increase in the deoxygenated hemoglobin (HbR) during the stimulation by the use of laser speckle contrast imaging.

Speciation Mapping of Environmental Samples Using XANES Imaging

EPA Science Inventory

Fast X-ray detectors with large solid angles and high dynamic ranges open the door to XANES imaging, in which millions of spectra are collected to image the speciation of metals at micrometre resolution, over areas up to several square centimetres. This paper explores how such mu...

Accuracy Analysis for Automatic Orientation of a Tumbling Oblique Viewing Sensor System

NASA Astrophysics Data System (ADS)

Stebner, K.; Wieden, A.

2014-03-01

Dynamic camera systems with moving parts are difficult to handle in photogrammetric workflow, because it is not ensured that the dynamics are constant over the recording period. Minimum changes of the camera's orientation greatly influence the projection of oblique images. In this publication these effects - originating from the kinematic chain of a dynamic camera system - are analysed and validated. A member of the Modular Airborne Camera System family - MACS-TumbleCam - consisting of a vertical viewing and a tumbling oblique camera was used for this investigation. Focus is on dynamic geometric modeling and the stability of the kinematic chain. To validate the experimental findings, the determined parameters are applied to the exterior orientation of an actual aerial image acquisition campaign using MACS-TumbleCam. The quality of the parameters is sufficient for direct georeferencing of oblique image data from the orientation information of a synchronously captured vertical image dataset. Relative accuracy for the oblique data set ranges from 1.5 pixels when using all images of the image block to 0.3 pixels when using only adjacent images.

Quantitative imaging of heterogeneous dynamics in drying and aging paints

PubMed Central

van der Kooij, Hanne M.; Fokkink, Remco; van der Gucht, Jasper; Sprakel, Joris

2016-01-01

Drying and aging paint dispersions display a wealth of complex phenomena that make their study fascinating yet challenging. To meet the growing demand for sustainable, high-quality paints, it is essential to unravel the microscopic mechanisms underlying these phenomena. Visualising the governing dynamics is, however, intrinsically difficult because the dynamics are typically heterogeneous and span a wide range of time scales. Moreover, the high turbidity of paints precludes conventional imaging techniques from reaching deep inside the paint. To address these challenges, we apply a scattering technique, Laser Speckle Imaging, as a versatile and quantitative tool to elucidate the internal dynamics, with microscopic resolution and spanning seven decades of time. We present a toolbox of data analysis and image processing methods that allows a tailored investigation of virtually any turbid dispersion, regardless of the geometry and substrate. Using these tools we watch a variety of paints dry and age with unprecedented detail. PMID:27682840

Video enhancement workbench: an operational real-time video image processing system

NASA Astrophysics Data System (ADS)

Yool, Stephen R.; Van Vactor, David L.; Smedley, Kirk G.

1993-01-01

Video image sequences can be exploited in real-time, giving analysts rapid access to information for military or criminal investigations. Video-rate dynamic range adjustment subdues fluctuations in image intensity, thereby assisting discrimination of small or low- contrast objects. Contrast-regulated unsharp masking enhances differentially shadowed or otherwise low-contrast image regions. Real-time removal of localized hotspots, when combined with automatic histogram equalization, may enhance resolution of objects directly adjacent. In video imagery corrupted by zero-mean noise, real-time frame averaging can assist resolution and location of small or low-contrast objects. To maximize analyst efficiency, lengthy video sequences can be screened automatically for low-frequency, high-magnitude events. Combined zoom, roam, and automatic dynamic range adjustment permit rapid analysis of facial features captured by video cameras recording crimes in progress. When trying to resolve small objects in murky seawater, stereo video places the moving imagery in an optimal setting for human interpretation.

Joint estimation of subject motion and tracer kinetic parameters of dynamic PET data in an EM framework

NASA Astrophysics Data System (ADS)

Jiao, Jieqing; Salinas, Cristian A.; Searle, Graham E.; Gunn, Roger N.; Schnabel, Julia A.

2012-02-01

Dynamic Positron Emission Tomography is a powerful tool for quantitative imaging of in vivo biological processes. The long scan durations necessitate motion correction, to maintain the validity of the dynamic measurements, which can be particularly challenging due to the low signal-to-noise ratio (SNR) and spatial resolution, as well as the complex tracer behaviour in the dynamic PET data. In this paper we develop a novel automated expectation-maximisation image registration framework that incorporates temporal tracer kinetic information to correct for inter-frame subject motion during dynamic PET scans. We employ the Zubal human brain phantom to simulate dynamic PET data using SORTEO (a Monte Carlo-based simulator), in order to validate the proposed method for its ability to recover imposed rigid motion. We have conducted a range of simulations using different noise levels, and corrupted the data with a range of rigid motion artefacts. The performance of our motion correction method is compared with pairwise registration using normalised mutual information as a voxel similarity measure (an approach conventionally used to correct for dynamic PET inter-frame motion based solely on intensity information). To quantify registration accuracy, we calculate the target registration error across the images. The results show that our new dynamic image registration method based on tracer kinetics yields better realignment of the simulated datasets, halving the target registration error when compared to the conventional method at small motion levels, as well as yielding smaller residuals in translation and rotation parameters. We also show that our new method is less affected by the low signal in the first few frames, which the conventional method based on normalised mutual information fails to realign.

Touch HDR: photograph enhancement by user controlled wide dynamic range adaptation

NASA Astrophysics Data System (ADS)

Verrall, Steve; Siddiqui, Hasib; Atanassov, Kalin; Goma, Sergio; Ramachandra, Vikas

2013-03-01

High Dynamic Range (HDR) technology enables photographers to capture a greater range of tonal detail. HDR is typically used to bring out detail in a dark foreground object set against a bright background. HDR technologies include multi-frame HDR and single-frame HDR. Multi-frame HDR requires the combination of a sequence of images taken at different exposures. Single-frame HDR requires histogram equalization post-processing of a single image, a technique referred to as local tone mapping (LTM). Images generated using HDR technology can look less natural than their non- HDR counterparts. Sometimes it is only desired to enhance small regions of an original image. For example, it may be desired to enhance the tonal detail of one subject's face while preserving the original background. The Touch HDR technique described in this paper achieves these goals by enabling selective blending of HDR and non-HDR versions of the same image to create a hybrid image. The HDR version of the image can be generated by either multi-frame or single-frame HDR. Selective blending can be performed as a post-processing step, for example, as a feature of a photo editor application, at any time after the image has been captured. HDR and non-HDR blending is controlled by a weighting surface, which is configured by the user through a sequence of touches on a touchscreen.

Computational model of lightness perception in high dynamic range imaging

NASA Astrophysics Data System (ADS)

Krawczyk, Grzegorz; Myszkowski, Karol; Seidel, Hans-Peter

2006-02-01

An anchoring theory of lightness perception by Gilchrist et al. [1999] explains many characteristics of human visual system such as lightness constancy and its spectacular failures which are important in the perception of images. The principal concept of this theory is the perception of complex scenes in terms of groups of consistent areas (frameworks). Such areas, following the gestalt theorists, are defined by the regions of common illumination. The key aspect of the image perception is the estimation of lightness within each framework through the anchoring to the luminance perceived as white, followed by the computation of the global lightness. In this paper we provide a computational model for automatic decomposition of HDR images into frameworks. We derive a tone mapping operator which predicts lightness perception of the real world scenes and aims at its accurate reproduction on low dynamic range displays. Furthermore, such a decomposition into frameworks opens new grounds for local image analysis in view of human perception.

Image gathering and digital restoration for fidelity and visual quality

NASA Technical Reports Server (NTRS)

Huck, Friedrich O.; Alter-Gartenberg, Rachel; Rahman, Zia-Ur

1991-01-01

The fidelity and resolution of the traditional Wiener restorations given in the prevalent digital processing literature can be significantly improved when the transformations between the continuous and discrete representations in image gathering and display are accounted for. However, the visual quality of these improved restorations also is more sensitive to the defects caused by aliasing artifacts, colored noise, and ringing near sharp edges. In this paper, these visual defects are characterized, and methods for suppressing them are presented. It is demonstrated how the visual quality of fidelity-maximized images can be improved when (1) the image-gathering system is specifically designed to enhance the performance of the image-restoration algorithm, and (2) the Wiener filter is combined with interactive Gaussian smoothing, synthetic high edge enhancement, and nonlinear tone-scale transformation. The nonlinear transformation is used primarily to enhance the spatial details that are often obscurred when the normally wide dynamic range of natural radiance fields is compressed into the relatively narrow dynamic range of film and other displays.

Evaluation of a gamma camera system for the RITS-6 accelerator using the self-magnetic pinch diode

NASA Astrophysics Data System (ADS)

Webb, Timothy J.; Kiefer, Mark L.; Gignac, Raymond; Baker, Stuart A.

2015-08-01

The self-magnetic pinch (SMP) diode is an intense radiographic source fielded on the Radiographic Integrated Test Stand (RITS-6) accelerator at Sandia National Laboratories in Albuquerque, NM. The accelerator is an inductive voltage adder (IVA) that can operate from 2-10 MV with currents up to 160 kA (at 7 MV). The SMP diode consists of an annular cathode separated from a flat anode, holding the bremsstrahlung conversion target, by a vacuum gap. Until recently the primary imaging diagnostic utilized image plates (storage phosphors) which has generally low DQE at these photon energies along with other problems. The benefits of using image plates include a high-dynamic range, good spatial resolution, and ease of use. A scintillator-based X-ray imaging system or "gamma camera" has been fielded in front of RITS and the SMP diode which has been able to provide vastly superior images in terms of signal-to-noise with similar resolution and acceptable dynamic range.

Design considerations for a new, high resolution Micro-Angiographic Fluoroscope based on a CMOS sensor (MAF-CMOS).

PubMed

Loughran, Brendan; Swetadri Vasan, S N; Singh, Vivek; Ionita, Ciprian N; Jain, Amit; Bednarek, Daniel R; Titus, Albert; Rudin, Stephen

2013-03-06

The detectors that are used for endovascular image-guided interventions (EIGI), particularly for neurovascular interventions, do not provide clinicians with adequate visualization to ensure the best possible treatment outcomes. Developing an improved x-ray imaging detector requires the determination of estimated clinical x-ray entrance exposures to the detector. The range of exposures to the detector in clinical studies was found for the three modes of operation: fluoroscopic mode, high frame-rate digital angiographic mode (HD fluoroscopic mode), and DSA mode. Using these estimated detector exposure ranges and available CMOS detector technical specifications, design requirements were developed to pursue a quantum limited, high resolution, dynamic x-ray detector based on a CMOS sensor with 50 μm pixel size. For the proposed MAF-CMOS, the estimated charge collected within the full exposure range was found to be within the estimated full well capacity of the pixels. Expected instrumentation noise for the proposed detector was estimated to be 50-1,300 electrons. Adding a gain stage such as a light image intensifier would minimize the effect of the estimated instrumentation noise on total image noise but may not be necessary to ensure quantum limited detector operation at low exposure levels. A recursive temporal filter may decrease the effective total noise by 2 to 3 times, allowing for the improved signal to noise ratios at the lowest estimated exposures despite consequent loss in temporal resolution. This work can serve as a guide for further development of dynamic x-ray imaging prototypes or improvements for existing dynamic x-ray imaging systems.

Shack-Hartmann wavefront sensor with large dynamic range by adaptive spot search method.

PubMed

Shinto, Hironobu; Saita, Yusuke; Nomura, Takanori

2016-07-10

A Shack-Hartmann wavefront sensor (SHWFS) that consists of a microlens array and an image sensor has been used to measure the wavefront aberrations of human eyes. However, a conventional SHWFS has finite dynamic range depending on the diameter of the each microlens. The dynamic range cannot be easily expanded without a decrease of the spatial resolution. In this study, an adaptive spot search method to expand the dynamic range of an SHWFS is proposed. In the proposed method, spots are searched with the help of their approximate displacements measured with low spatial resolution and large dynamic range. By the proposed method, a wavefront can be correctly measured even if the spot is beyond the detection area. The adaptive spot search method is realized by using the special microlens array that generates both spots and discriminable patterns. The proposed method enables expanding the dynamic range of an SHWFS with a single shot and short processing time. The performance of the proposed method is compared with that of a conventional SHWFS by optical experiments. Furthermore, the dynamic range of the proposed method is quantitatively evaluated by numerical simulations.

Automatic dynamic range adjustment for ultrasound B-mode imaging.

PubMed

Lee, Yeonhwa; Kang, Jinbum; Yoo, Yangmo

2015-02-01

In medical ultrasound imaging, dynamic range (DR) is defined as the difference between the maximum and minimum values of the displayed signal to display and it is one of the most essential parameters that determine its image quality. Typically, DR is given with a fixed value and adjusted manually by operators, which leads to low clinical productivity and high user dependency. Furthermore, in 3D ultrasound imaging, DR values are unable to be adjusted during 3D data acquisition. A histogram matching method, which equalizes the histogram of an input image based on that from a reference image, can be applied to determine the DR value. However, it could be lead to an over contrasted image. In this paper, a new Automatic Dynamic Range Adjustment (ADRA) method is presented that adaptively adjusts the DR value by manipulating input images similar to a reference image. The proposed ADRA method uses the distance ratio between the log average and each extreme value of a reference image. To evaluate the performance of the ADRA method, the similarity between the reference and input images was measured by computing a correlation coefficient (CC). In in vivo experiments, the CC values were increased by applying the ADRA method from 0.6872 to 0.9870 and from 0.9274 to 0.9939 for kidney and liver data, respectively, compared to the fixed DR case. In addition, the proposed ADRA method showed to outperform the histogram matching method with in vivo liver and kidney data. When using 3D abdominal data with 70 frames, while the CC value from the ADRA method is slightly increased (i.e., 0.6%), the proposed method showed improved image quality in the c-plane compared to its fixed counterpart, which suffered from a shadow artifact. These results indicate that the proposed method can enhance image quality in 2D and 3D ultrasound B-mode imaging by improving the similarity between the reference and input images while eliminating unnecessary manual interaction by the user. Copyright © 2014 Elsevier B.V. All rights reserved.

A CMOS-based large-area high-resolution imaging system for high-energy x-ray applications

NASA Astrophysics Data System (ADS)

Rodricks, Brian; Fowler, Boyd; Liu, Chiao; Lowes, John; Haeffner, Dean; Lienert, Ulrich; Almer, John

2008-08-01

CCDs have been the primary sensor in imaging systems for x-ray diffraction and imaging applications in recent years. CCDs have met the fundamental requirements of low noise, high-sensitivity, high dynamic range and spatial resolution necessary for these scientific applications. State-of-the-art CMOS image sensor (CIS) technology has experienced dramatic improvements recently and their performance is rivaling or surpassing that of most CCDs. The advancement of CIS technology is at an ever-accelerating pace and is driven by the multi-billion dollar consumer market. There are several advantages of CIS over traditional CCDs and other solid-state imaging devices; they include low power, high-speed operation, system-on-chip integration and lower manufacturing costs. The combination of superior imaging performance and system advantages makes CIS a good candidate for high-sensitivity imaging system development. This paper will describe a 1344 x 1212 CIS imaging system with a 19.5μm pitch optimized for x-ray scattering studies at high-energies. Fundamental metrics of linearity, dynamic range, spatial resolution, conversion gain, sensitivity are estimated. The Detective Quantum Efficiency (DQE) is also estimated. Representative x-ray diffraction images are presented. Diffraction images are compared against a CCD-based imaging system.

Towards clinical computed ultrasound tomography in echo-mode: Dynamic range artefact reduction.

PubMed

Jaeger, Michael; Frenz, Martin

2015-09-01

Computed ultrasound tomography in echo-mode (CUTE) allows imaging the speed of sound inside tissue using hand-held pulse-echo ultrasound. This technique is based on measuring the changing local phase of beamformed echoes when changing the transmit beam steering angle. Phantom results have shown a spatial resolution and contrast that could qualify CUTE as a promising novel diagnostic modality in combination with B-mode ultrasound. Unfortunately, the large intensity range of several tens of dB that is encountered in clinical images poses difficulties to echo phase tracking and results in severe artefacts. In this paper we propose a modification to the original technique by which more robust echo tracking can be achieved, and we demonstrate in phantom experiments that dynamic range artefacts are largely eliminated. Dynamic range artefact reduction also allowed for the first time a clinical implementation of CUTE with sufficient contrast to reproducibly distinguish the different speed of sound in different tissue layers of the abdominal wall and the neck. Copyright © 2015. Published by Elsevier B.V.

Comparison of magnetic resonance imaging-compatible optical detectors for in-magnet tissue spectroscopy: photodiodes versus silicon photomultipliers

PubMed Central

El-Ghussein, Fadi; Jiang, Shudong; Pogue, Brian W.; Paulsen, Keith D.

2014-01-01

Abstract. Tissue spectroscopy inside the magnetic resonance imaging (MRI) system adds a significant value by measuring fast vascular hemoglobin responses or completing spectroscopic identification of diagnostically relevant molecules. Advances in this type of spectroscopy instrumentation have largely focused on fiber coupling into and out of the MRI; however, nonmagnetic detectors can now be placed inside the scanner with signal amplification performed remotely to the high field environment for optimized light detection. In this study, the two possible detector options, such as silicon photodiodes (PD) and silicon photomultipliers (SiPM), were systematically examined for dynamic range and wavelength performance. Results show that PDs offer 108 (160 dB) dynamic range with sensitivity down to 1 pW, whereas SiPMs have 107 (140 dB) dynamic range and sensitivity down to 10 pW. A second major difference is the spectral sensitivity of the two detectors. Here, wavelengths in the 940 nm range are efficiently captured by PDs (but not SiPMs), likely making them the superior choice for broadband spectroscopy guided by MRI. PMID:25006986

Holographic recording properties in thick films of ULSH-500 photopolymer

NASA Astrophysics Data System (ADS)

Waldman, David A.; Li, H.-Y. S.; Cetin, Erdem A.

1998-06-01

The photopolymer holographic recording materials, ULSH-500, based upon cationic ring-opening polymerization, has been further optimized for recording in an increased film thickness of 200 micrometers . The dynamic range attained, at least M/# equals 16, is substantially greater than previously reported, while concurrently the inherent low transverse shrinkage and high sensitivity characteristics of the material have been retained. Dynamic range or cumulative grating strength, (Sigma) (eta) i0.5, has been determined from co-locationally recorded peristrophic and angle multiplexed plane-wave gratings which exhibit low diffraction efficiencies between about 0.1 and 0.2%. Good Bragg selectivity consistent with the imaged thickness and sinc2 function behavior is observed for the multiplexed holograms, and both the angular response and the diffraction efficiency are stable without the need for post-imaging fixing procedures. Sensitivity is in the range of 1 to 10 cm/mJ, and the refractive index modulation achievable during consumption of the accessible dynamic range is n1 equals 1.3 X 10-2 at the read wavelength of 514.5 nm.

Active confocal imaging for visual prostheses

PubMed Central

Jung, Jae-Hyun; Aloni, Doron; Yitzhaky, Yitzhak; Peli, Eli

2014-01-01

There are encouraging advances in prosthetic vision for the blind, including retinal and cortical implants, and other “sensory substitution devices” that use tactile or electrical stimulation. However, they all have low resolution, limited visual field, and can display only few gray levels (limited dynamic range), severely restricting their utility. To overcome these limitations, image processing or the imaging system could emphasize objects of interest and suppress the background clutter. We propose an active confocal imaging system based on light-field technology that will enable a blind user of any visual prosthesis to efficiently scan, focus on, and “see” only an object of interest while suppressing interference from background clutter. The system captures three-dimensional scene information using a light-field sensor and displays only an in-focused plane with objects in it. After capturing a confocal image, a de-cluttering process removes the clutter based on blur difference. In preliminary experiments we verified the positive impact of confocal-based background clutter removal on recognition of objects in low resolution and limited dynamic range simulated phosphene images. Using a custom-made multiple-camera system, we confirmed that the concept of a confocal de-cluttered image can be realized effectively using light field imaging. PMID:25448710

Enhanced visual perception through tone mapping

NASA Astrophysics Data System (ADS)

Harrison, Andre; Mullins, Linda L.; Raglin, Adrienne; Etienne-Cummings, Ralph

2016-05-01

Tone mapping operators compress high dynamic range images to improve the picture quality on a digital display when the dynamic range of the display is lower than that of the image. However, tone mapping operators have been largely designed and evaluated based on the aesthetic quality of the resulting displayed image or how perceptually similar the compressed image appears relative to the original scene. They also often require per image tuning of parameters depending on the content of the image. In military operations, however, the amount of information that can be perceived is more important than the aesthetic quality of the image and any parameter adjustment needs to be as automated as possible regardless of the content of the image. We have conducted two studies to evaluate the perceivable detail of a set of tone mapping algorithms, and we apply our findings to develop and test an automated tone mapping algorithm that demonstrates a consistent improvement in the amount of perceived detail. An automated, and thereby predictable, tone mapping method enables a consistent presentation of perceivable features, can reduce the bandwidth required to transmit the imagery, and can improve the accessibility of the data by reducing the needed expertise of the analyst(s) viewing the imagery.

Optimized lighting method of applying shaped-function signal for increasing the dynamic range of LED-multispectral imaging system

NASA Astrophysics Data System (ADS)

Yang, Xue; Hu, Yajia; Li, Gang; Lin, Ling

2018-02-01

This paper proposes an optimized lighting method of applying a shaped-function signal for increasing the dynamic range of light emitting diode (LED)-multispectral imaging system. The optimized lighting method is based on the linear response zone of the analog-to-digital conversion (ADC) and the spectral response of the camera. The auxiliary light at a higher sensitivity-camera area is introduced to increase the A/D quantization levels that are within the linear response zone of ADC and improve the signal-to-noise ratio. The active light is modulated by the shaped-function signal to improve the gray-scale resolution of the image. And the auxiliary light is modulated by the constant intensity signal, which is easy to acquire the images under the active light irradiation. The least square method is employed to precisely extract the desired images. One wavelength in multispectral imaging based on LED illumination was taken as an example. It has been proven by experiments that the gray-scale resolution and the accuracy of information of the images acquired by the proposed method were both significantly improved. The optimum method opens up avenues for the hyperspectral imaging of biological tissue.

Optimized lighting method of applying shaped-function signal for increasing the dynamic range of LED-multispectral imaging system.

PubMed

Yang, Xue; Hu, Yajia; Li, Gang; Lin, Ling

2018-02-01

This paper proposes an optimized lighting method of applying a shaped-function signal for increasing the dynamic range of light emitting diode (LED)-multispectral imaging system. The optimized lighting method is based on the linear response zone of the analog-to-digital conversion (ADC) and the spectral response of the camera. The auxiliary light at a higher sensitivity-camera area is introduced to increase the A/D quantization levels that are within the linear response zone of ADC and improve the signal-to-noise ratio. The active light is modulated by the shaped-function signal to improve the gray-scale resolution of the image. And the auxiliary light is modulated by the constant intensity signal, which is easy to acquire the images under the active light irradiation. The least square method is employed to precisely extract the desired images. One wavelength in multispectral imaging based on LED illumination was taken as an example. It has been proven by experiments that the gray-scale resolution and the accuracy of information of the images acquired by the proposed method were both significantly improved. The optimum method opens up avenues for the hyperspectral imaging of biological tissue.

Pixel Paradise

NASA Technical Reports Server (NTRS)

1998-01-01

PixelVision, Inc., has developed a series of integrated imaging engines capable of high-resolution image capture at dynamic speeds. This technology was used originally at Jet Propulsion Laboratory in a series of imaging engines for a NASA mission to Pluto. By producing this integrated package, Charge-Coupled Device (CCD) technology has been made accessible to a wide range of users.

A Hybrid Shared-Memory Parallel Max-Tree Algorithm for Extreme Dynamic-Range Images.

PubMed

Moschini, Ugo; Meijster, Arnold; Wilkinson, Michael H F

2018-03-01

Max-trees, or component trees, are graph structures that represent the connected components of an image in a hierarchical way. Nowadays, many application fields rely on images with high-dynamic range or floating point values. Efficient sequential algorithms exist to build trees and compute attributes for images of any bit depth. However, we show that the current parallel algorithms perform poorly already with integers at bit depths higher than 16 bits per pixel. We propose a parallel method combining the two worlds of flooding and merging max-tree algorithms. First, a pilot max-tree of a quantized version of the image is built in parallel using a flooding method. Later, this structure is used in a parallel leaf-to-root approach to compute efficiently the final max-tree and to drive the merging of the sub-trees computed by the threads. We present an analysis of the performance both on simulated and actual 2D images and 3D volumes. Execution times are about better than the fastest sequential algorithm and speed-up goes up to on 64 threads.

Performance evaluation of objective quality metrics for HDR image compression

NASA Astrophysics Data System (ADS)

Valenzise, Giuseppe; De Simone, Francesca; Lauga, Paul; Dufaux, Frederic

2014-09-01

Due to the much larger luminance and contrast characteristics of high dynamic range (HDR) images, well-known objective quality metrics, widely used for the assessment of low dynamic range (LDR) content, cannot be directly applied to HDR images in order to predict their perceptual fidelity. To overcome this limitation, advanced fidelity metrics, such as the HDR-VDP, have been proposed to accurately predict visually significant differences. However, their complex calibration may make them difficult to use in practice. A simpler approach consists in computing arithmetic or structural fidelity metrics, such as PSNR and SSIM, on perceptually encoded luminance values but the performance of quality prediction in this case has not been clearly studied. In this paper, we aim at providing a better comprehension of the limits and the potentialities of this approach, by means of a subjective study. We compare the performance of HDR-VDP to that of PSNR and SSIM computed on perceptually encoded luminance values, when considering compressed HDR images. Our results show that these simpler metrics can be effectively employed to assess image fidelity for applications such as HDR image compression.

The FOXSI sounding rocket: Latest analysis and results

NASA Astrophysics Data System (ADS)

Buitrago-Casas, Juan Camilo; Glesener, Lindsay; Christe, Steven; Krucker, Sam; Ishikawa, Shin-Nosuke; Takahashi, Tadayuki; Ramsey, Brian; Han, Raymond

2016-05-01

Hard X-ray (HXR) observations are a linchpin for studying particle acceleration and hot thermal plasma emission in the solar corona. Current and past indirectly imaging instruments lack the sensitivity and dynamic range needed to observe faint HXR signatures, especially in the presences of brighter sources. These limitations are overcome by using HXR direct focusing optics coupled with semiconductor detectors. The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket experiment is a state of the art solar telescope that develops and applies these capabilities.The FOXSI sounding rocket has successfully flown twice, observing active regions, microflares, and areas of the quiet-Sun. Thanks to its far superior imaging dynamic range, FOXSI performs cleaner hard X-ray imaging spectroscopy than previous instruments that use indirect imaging methods like RHESSI.We present a description of the FOXSI rocket payload, paying attention to the optics and semiconductor detectors calibrations, as well as the upgrades made for the second flight. We also introduce some of the latest FOXSI data analysis, including imaging spectroscopy of microflares and active regions observed during the two flights, and the differential emission measure distribution of the nonflaring corona.

Low-voltage 96 dB snapshot CMOS image sensor with 4.5 nW power dissipation per pixel.

PubMed

Spivak, Arthur; Teman, Adam; Belenky, Alexander; Yadid-Pecht, Orly; Fish, Alexander

2012-01-01

Modern "smart" CMOS sensors have penetrated into various applications, such as surveillance systems, bio-medical applications, digital cameras, cellular phones and many others. Reducing the power of these sensors continuously challenges designers. In this paper, a low power global shutter CMOS image sensor with Wide Dynamic Range (WDR) ability is presented. This sensor features several power reduction techniques, including a dual voltage supply, a selective power down, transistors with different threshold voltages, a non-rationed logic, and a low voltage static memory. A combination of all these approaches has enabled the design of the low voltage "smart" image sensor, which is capable of reaching a remarkable dynamic range, while consuming very low power. The proposed power-saving solutions have allowed the maintenance of the standard architecture of the sensor, reducing both the time and the cost of the design. In order to maintain the image quality, a relation between the sensor performance and power has been analyzed and a mathematical model, describing the sensor Signal to Noise Ratio (SNR) and Dynamic Range (DR) as a function of the power supplies, is proposed. The described sensor was implemented in a 0.18 um CMOS process and successfully tested in the laboratory. An SNR of 48 dB and DR of 96 dB were achieved with a power dissipation of 4.5 nW per pixel.

Low-Voltage 96 dB Snapshot CMOS Image Sensor with 4.5 nW Power Dissipation per Pixel

PubMed Central

Spivak, Arthur; Teman, Adam; Belenky, Alexander; Yadid-Pecht, Orly; Fish, Alexander

2012-01-01

Modern “smart” CMOS sensors have penetrated into various applications, such as surveillance systems, bio-medical applications, digital cameras, cellular phones and many others. Reducing the power of these sensors continuously challenges designers. In this paper, a low power global shutter CMOS image sensor with Wide Dynamic Range (WDR) ability is presented. This sensor features several power reduction techniques, including a dual voltage supply, a selective power down, transistors with different threshold voltages, a non-rationed logic, and a low voltage static memory. A combination of all these approaches has enabled the design of the low voltage “smart” image sensor, which is capable of reaching a remarkable dynamic range, while consuming very low power. The proposed power-saving solutions have allowed the maintenance of the standard architecture of the sensor, reducing both the time and the cost of the design. In order to maintain the image quality, a relation between the sensor performance and power has been analyzed and a mathematical model, describing the sensor Signal to Noise Ratio (SNR) and Dynamic Range (DR) as a function of the power supplies, is proposed. The described sensor was implemented in a 0.18 um CMOS process and successfully tested in the laboratory. An SNR of 48 dB and DR of 96 dB were achieved with a power dissipation of 4.5 nW per pixel. PMID:23112588

Motion-adaptive spatio-temporal regularization for accelerated dynamic MRI.

PubMed

Asif, M Salman; Hamilton, Lei; Brummer, Marijn; Romberg, Justin

2013-09-01

Accelerated magnetic resonance imaging techniques reduce signal acquisition time by undersampling k-space. A fundamental problem in accelerated magnetic resonance imaging is the recovery of quality images from undersampled k-space data. Current state-of-the-art recovery algorithms exploit the spatial and temporal structures in underlying images to improve the reconstruction quality. In recent years, compressed sensing theory has helped formulate mathematical principles and conditions that ensure recovery of (structured) sparse signals from undersampled, incoherent measurements. In this article, a new recovery algorithm, motion-adaptive spatio-temporal regularization, is presented that uses spatial and temporal structured sparsity of MR images in the compressed sensing framework to recover dynamic MR images from highly undersampled k-space data. In contrast to existing algorithms, our proposed algorithm models temporal sparsity using motion-adaptive linear transformations between neighboring images. The efficiency of motion-adaptive spatio-temporal regularization is demonstrated with experiments on cardiac magnetic resonance imaging for a range of reduction factors. Results are also compared with k-t FOCUSS with motion estimation and compensation-another recently proposed recovery algorithm for dynamic magnetic resonance imaging. . Copyright © 2012 Wiley Periodicals, Inc.

Scanning Shack-Hartmann wavefront sensor

NASA Astrophysics Data System (ADS)

Molebny, Vasyl V.

2004-09-01

Criss-crossing of focal images is the cause of a narrow dynamic range in Shack-Hartmann sensors. Practically, aberration range wider than +/-3 diopters can not be measured. A method has been proposed for ophthalmologic applications using a rarefied lenslet array through which a wave front is projected with the successive step-by-step changing of the global tilt. The data acquired in each step are accumulated and processed. In experimental setup, a doubled dynamic range was achieved with four steps of wave front tilting.

Non-Linearity in Wide Dynamic Range CMOS Image Sensors Utilizing a Partial Charge Transfer Technique.

PubMed

Shafie, Suhaidi; Kawahito, Shoji; Halin, Izhal Abdul; Hasan, Wan Zuha Wan

2009-01-01

The partial charge transfer technique can expand the dynamic range of a CMOS image sensor by synthesizing two types of signal, namely the long and short accumulation time signals. However the short accumulation time signal obtained from partial transfer operation suffers of non-linearity with respect to the incident light. In this paper, an analysis of the non-linearity in partial charge transfer technique has been carried, and the relationship between dynamic range and the non-linearity is studied. The results show that the non-linearity is caused by two factors, namely the current diffusion, which has an exponential relation with the potential barrier, and the initial condition of photodiodes in which it shows that the error in the high illumination region increases as the ratio of the long to the short accumulation time raises. Moreover, the increment of the saturation level of photodiodes also increases the error in the high illumination region.

Automated assessment of blood flow in developing embryonic hearts by extending dynamic range of Doppler OCT using a MHz FDML swept laser source (Conference Presentation)

NASA Astrophysics Data System (ADS)

Elahi, Sahar; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.

2017-02-01

Altered hemodynamics in developing embryonic hearts lead to congenital heart diseases, motivating close monitoring of blood flow over several stages of development. Doppler OCT can assess blood flow in tubular hearts, but the maximum velocity increases drastically during the period of cardiac cushion (valve precursors) formation. Therefore, the limited dynamic range of Doppler OCT velocity measurement makes it difficult to conduct longitudinal studies without phase wrapping at high velocities or loss of sensitivity to slow velocities. We have built a high-speed OCT system using an FDML laser (Optores GmbH, Germany) at a sweep rate of 1.68 MHz (axial resolution - 12 μm, sensitivity - 105 dB, phase stability - 17 mrad). The speed of this OCT system allows us to acquire high-density B-scans to obtain an extended velocity dynamic range without sacrificing the frame rate. The extended dynamic range within a frame is achieved by varying the A-scan interval at which the phase difference is found, enabling detection of velocities ranging from tens of microns per second to hundreds of mm per second. The extra lines in a frame can also be utilized to improve the structural and Doppler images via complex averaging. In structural images where presence of blood causes additional scattering, complex averaging helps retrieve features located deeper in the tissue. Moreover, high-density frames can be registered to 4D volumes to determine the orthogonal direction of flow and calculate shear stress. In conclusion, our high-speed OCT system will enable automated Doppler imaging of embryonic hearts in cohort studies.

Digital Compositing Techniques for Coronal Imaging (Invited review)

NASA Astrophysics Data System (ADS)

Espenak, F.

2000-04-01

The solar corona exhibits a huge range in brightness which cannot be captured in any single photographic exposure. Short exposures show the bright inner corona and prominences, while long exposures reveal faint details in equatorial streamers and polar brushes. For many years, radial gradient filters and other analog techniques have been used to compress the corona's dynamic range in order to study its morphology. Such techniques demand perfect pointing and tracking during the eclipse, and can be difficult to calibrate. In the past decade, the speed, memory and hard disk capacity of personal computers have rapidly increased as prices continue to drop. It is now possible to perform sophisticated image processing of eclipse photographs on commercially available CPU's. Software programs such as Adobe Photoshop permit combining multiple eclipse photographs into a composite image which compresses the corona's dynamic range and can reveal subtle features and structures. Algorithms and digital techniques used for processing 1998 eclipse photographs will be discussed which are equally applicable to the recent eclipse of 1999 August 11.

ImSyn: photonic image synthesis applied to synthetic aperture radar, microscopy, and ultrasound imaging

NASA Astrophysics Data System (ADS)

Turpin, Terry M.; Lafuse, James L.

1993-02-01

ImSynTM is an image synthesis technology, developed and patented by Essex Corporation. ImSynTM can provide compact, low cost, and low power solutions to some of the most difficult image synthesis problems existing today. The inherent simplicity of ImSynTM enables the manufacture of low cost and reliable photonic systems for imaging applications ranging from airborne reconnaissance to doctor's office ultrasound. The initial application of ImSynTM technology has been to SAR processing; however, it has a wide range of applications such as: image correlation, image compression, acoustic imaging, x-ray tomographic (CAT, PET, SPECT), magnetic resonance imaging (MRI), microscopy, range- doppler mapping (extended TDOA/FDOA). This paper describes ImSynTM in terms of synthetic aperture microscopy and then shows how the technology can be extended to ultrasound and synthetic aperture radar. The synthetic aperture microscope (SAM) enables high resolution three dimensional microscopy with greater dynamic range than real aperture microscopes. SAM produces complex image data, enabling the use of coherent image processing techniques. Most importantly SAM produces the image data in a form that is easily manipulated by a digital image processing workstation.

Event-Based Tone Mapping for Asynchronous Time-Based Image Sensor

PubMed Central

Simon Chane, Camille; Ieng, Sio-Hoi; Posch, Christoph; Benosman, Ryad B.

2016-01-01

The asynchronous time-based neuromorphic image sensor ATIS is an array of autonomously operating pixels able to encode luminance information with an exceptionally high dynamic range (>143 dB). This paper introduces an event-based methodology to display data from this type of event-based imagers, taking into account the large dynamic range and high temporal accuracy that go beyond available mainstream display technologies. We introduce an event-based tone mapping methodology for asynchronously acquired time encoded gray-level data. A global and a local tone mapping operator are proposed. Both are designed to operate on a stream of incoming events rather than on time frame windows. Experimental results on real outdoor scenes are presented to evaluate the performance of the tone mapping operators in terms of quality, temporal stability, adaptation capability, and computational time. PMID:27642275

High dynamic range infrared radiometry and imaging

NASA Technical Reports Server (NTRS)

Coon, Darryl D.; Karunasiri, R. P. G.; Bandara, K. M. S. V.

1988-01-01

The use is described of cryogenically cooled, extrinsic silicon infrared detectors in an unconventional mode of operation which offers an unusually large dynamic range. The system performs intensity-to-frequency conversion at the focal plane via simple circuits with very low power consumption. The incident IR intensity controls the repetition rate of short duration output pulses over a pulse rate dynamic range of about 10(6). Theory indicates the possibility of monotonic and approx. linear response over the full dynamic range. A comparison between the theoretical and the experimental results shows that the model provides a reasonably good description of experimental data. Some measurements of survivability with a very intense IR source were made on these devices and found to be very encouraging. Evidence continues to indicate that some variations in interpulse time intervals are deterministic rather than probabilistic.

Quantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryos.

PubMed

Zhao, Ziqing W; White, Melanie D; Bissiere, Stephanie; Levi, Valeria; Plachta, Nicolas

2016-12-23

Probing dynamic processes occurring within the cell nucleus at the quantitative level has long been a challenge in mammalian biology. Advances in bio-imaging techniques over the past decade have enabled us to directly visualize nuclear processes in situ with unprecedented spatial and temporal resolution and single-molecule sensitivity. Here, using transcription as our primary focus, we survey recent imaging studies that specifically emphasize the quantitative understanding of nuclear dynamics in both time and space. These analyses not only inform on previously hidden physical parameters and mechanistic details, but also reveal a hierarchical organizational landscape for coordinating a wide range of transcriptional processes shared by mammalian systems of varying complexity, from single cells to whole embryos.

Revealing glacier flow and surge dynamics from animated satellite image sequences: examples from the Karakoram

NASA Astrophysics Data System (ADS)

Paul, F.

2015-04-01

Although animated images are very popular on the Internet, they have so far found only limited use for glaciological applications. With long time-series of satellite images becoming increasingly available and glaciers being well recognized for their rapid changes and variable flow dynamics, animated sequences of multiple satellite images reveal glacier dynamics in a time-lapse mode, making the otherwise slow changes of glacier movement visible and understandable for a wide public. For this study animated image sequences were created from freely available image quick-looks of orthorectified Landsat scenes for four regions in the central Karakoram mountain range. The animations play automatically in a web-browser and might help to demonstrate glacier flow dynamics for educational purposes. The animations revealed highly complex patterns of glacier flow and surge dynamics over a 15-year time period (1998-2013). In contrast to other regions, surging glaciers in the Karakoram are often small (around 10 km2), steep, debris free, and advance for several years at comparably low annual rates (a few hundred m a-1). The advance periods of individual glaciers are generally out of phase, indicating a limited climatic control on their dynamics. On the other hand, nearly all other glaciers in the region are either stable or slightly advancing, indicating balanced or even positive mass budgets over the past few years to decades.

Image sensor with high dynamic range linear output

NASA Technical Reports Server (NTRS)

Yadid-Pecht, Orly (Inventor); Fossum, Eric R. (Inventor)

2007-01-01

Designs and operational methods to increase the dynamic range of image sensors and APS devices in particular by achieving more than one integration times for each pixel thereof. An APS system with more than one column-parallel signal chains for readout are described for maintaining a high frame rate in readout. Each active pixel is sampled for multiple times during a single frame readout, thus resulting in multiple integration times. The operation methods can also be used to obtain multiple integration times for each pixel with an APS design having a single column-parallel signal chain for readout. Furthermore, analog-to-digital conversion of high speed and high resolution can be implemented.

A Test Strategy for High Resolution Image Scanners.

DTIC Science & Technology

1983-10-01

for multivariate analysis. Holt, Richart and Winston, Inc., New York. Graybill , F.A., 1961: An introduction to linear statistical models . SVolume I...i , j i -(7) 02 1 )2 y 4n .i ij 13 The linear estimation model for the polynomial coefficients can be set up as - =; =(8) with T = ( x’ . . X-nn "X...Resolution Image Scanner MTF Geometrical and radiometric performance Dynamic range, linearity , noise - Dynamic scanning errors Response uniformity Skewness of

A JPEG backward-compatible HDR image compression

NASA Astrophysics Data System (ADS)

Korshunov, Pavel; Ebrahimi, Touradj

2012-10-01

High Dynamic Range (HDR) imaging is expected to become one of the technologies that could shape next generation of consumer digital photography. Manufacturers are rolling out cameras and displays capable of capturing and rendering HDR images. The popularity and full public adoption of HDR content is however hindered by the lack of standards in evaluation of quality, file formats, and compression, as well as large legacy base of Low Dynamic Range (LDR) displays that are unable to render HDR. To facilitate wide spread of HDR usage, the backward compatibility of HDR technology with commonly used legacy image storage, rendering, and compression is necessary. Although many tone-mapping algorithms were developed for generating viewable LDR images from HDR content, there is no consensus on which algorithm to use and under which conditions. This paper, via a series of subjective evaluations, demonstrates the dependency of perceived quality of the tone-mapped LDR images on environmental parameters and image content. Based on the results of subjective tests, it proposes to extend JPEG file format, as the most popular image format, in a backward compatible manner to also deal with HDR pictures. To this end, the paper provides an architecture to achieve such backward compatibility with JPEG and demonstrates efficiency of a simple implementation of this framework when compared to the state of the art HDR image compression.

Biodynamic Doppler imaging of subcellular motion inside 3D living tissue culture and biopsies (Conference Presentation)

NASA Astrophysics Data System (ADS)

Nolte, David D.

2016-03-01

Biodynamic imaging is an emerging 3D optical imaging technology that probes up to 1 mm deep inside three-dimensional living tissue using short-coherence dynamic light scattering to measure the intracellular motions of cells inside their natural microenvironments. Biodynamic imaging is label-free and non-invasive. The information content of biodynamic imaging is captured through tissue dynamics spectroscopy that displays the changes in the Doppler signatures from intracellular constituents in response to applied compounds. The affected dynamic intracellular mechanisms include organelle transport, membrane undulations, cytoskeletal restructuring, strain at cellular adhesions, cytokinesis, mitosis, exo- and endo-cytosis among others. The development of 3D high-content assays such as biodynamic profiling can become a critical new tool for assessing efficacy of drugs and the suitability of specific types of tissue growth for drug discovery and development. The use of biodynamic profiling to predict clinical outcome of living biopsies to cancer therapeutics can be developed into a phenotypic companion diagnostic, as well as a new tool for therapy selection in personalized medicine. This invited talk will present an overview of the optical, physical and physiological processes involved in biodynamic imaging. Several different biodynamic imaging modalities include motility contrast imaging (MCI), tissue-dynamics spectroscopy (TDS) and tissue-dynamics imaging (TDI). A wide range of potential applications will be described that include process monitoring for 3D tissue culture, drug discovery and development, cancer therapy selection, embryo assessment for in-vitro fertilization and artificial reproductive technologies, among others.

Adaptive Optics For Imaging Bright Objects Next To Dim Ones

NASA Technical Reports Server (NTRS)

Shao, Michael; Yu, Jeffrey W.; Malbet, Fabien

1996-01-01

Adaptive optics used in imaging optical systems, according to proposal, to enhance high-dynamic-range images (images of bright objects next to dim objects). Designed to alter wavefronts to correct for effects of scattering of light from small bumps on imaging optics. Original intended application of concept in advanced camera installed on Hubble Space Telescope for imaging of such phenomena as large planets near stars other than Sun. Also applicable to other high-quality telescopes and cameras.

A-law/Mu-law Dynamic Range Compression Deconvolution (Preprint)

DTIC Science & Technology

2008-02-04

noise filtering via the spectrum proportionality filter, and second the signal deblurring via the inverse filter. In this process for regions when...is the joint image of motion impulse response and the noisy blurred image with signal to noise ratio 5, 6(A’) is the gray level recovered image...joint image of motion impulse response and the noisy blurred image with signal to noise ratio 5, (A’) the gray level recovered image using the A-law

Multi-frame X-ray Phase Contrast Imaging (MPCI) for Dynamic Experiments

NASA Astrophysics Data System (ADS)

Iverson, Adam; Carlson, Carl; Sanchez, Nathaniel; Jensen, Brian

2017-06-01

Recent advances in coupling synchrotron X-ray diagnostics to dynamic experiments are providing new information about the response of materials at extremes. For example, propagation based X-ray Phase Contrast Imaging (PCI) which is sensitive to differences in density has been successfully used to study a wide range of phenomena, e.g. jet-formation, compression of additive manufactured (AM) materials, and detonator dynamics. In this talk, we describe the current multi-frame X-ray phase contrast imaging (MPCI) system which allows up to eight frames per experiment, remote optimization, and an improved optical design that increases optical efficiency and accommodates dual-magnification during a dynamic event. Data will be presented that used the dual-magnification feature to obtain multiple images of an exploding foil initiator. In addition, results from static testing will be presented that used a multiple scintillator configuration required to extend the density retrieval to multi-constituent, or heterogeneous systems. The continued development of this diagnostic is fundamentally important to capabilities at the APS including IMPULSE and the Dynamic Compression Sector (DCS), and will benefit future facilities such as MaRIE at Los Alamos National Laboratory.

Results from the first flight of the Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket

NASA Astrophysics Data System (ADS)

Glesener, Lindsay; Christe, S.; Ishikawa, S.; Ramsey, B.; Takahashi, T.; Watanabe, S.; Saito, S.; Lin, R. P.; Krucker, S.; FOXSI Team

2013-07-01

Understanding electron acceleration in solar flares requires X-ray studies with greater sensitivity and dynamic range than are available with current solar hard X-ray observers (i.e. the RHESSI spacecraft). RHESSI employs an indirect Fourier imaging method that is intrinsically limited in dynamic range and therefore can rarely image faint coronal flare sources in the presence of bright footpoints. With greater sensitivity and dynamic range, electron acceleration sites in the corona could be studied in great detail. Both these capabilities can be advanced by the use of direct focusing optics. The recently flown Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload demonstrates the feasibility and usefulness of hard X-ray focusing optics for solar study. FOXSI features grazing-incidence replicated nickel optics from the NASA Marshall Space Flight Center and fine-pitch silicon strip detectors developed by the Astro-H team at JAXA/ISAS. FOXSI flew successfully on November 2, 2012, producing images and spectra of a microflare and performing a search for nonthermal emission (4-15 keV) from nanoflares in the quiet Sun. Nanoflares are a candidate for providing the required energy to heat the solar corona to its high temperature of a few million degrees. A future satellite version of FOXSI, featuring similar optics and detectors, could make detailed observations of hard X-rays from flare-accelerated electrons, identifying and characterizing particle acceleration sites and mapping out paths of energetic electrons as they leave these sites and propagate throughout the solar corona.

The Pearson-Readhead Survey of Compact Extragalactic Radio Sources from Space. I. The Images

NASA Astrophysics Data System (ADS)

Lister, M. L.; Tingay, S. J.; Murphy, D. W.; Piner, B. G.; Jones, D. L.; Preston, R. A.

2001-06-01

We present images from a space-VLBI survey using the facilities of the VLBI Space Observatory Programme (VSOP), drawing our sample from the well-studied Pearson-Readhead survey of extragalactic radio sources. Our survey has taken advantage of long space-VLBI baselines and large arrays of ground antennas, such as the Very Long Baseline Array and European VLBI Network, to obtain high-resolution images of 27 active galactic nuclei and to measure the core brightness temperatures of these sources more accurately than is possible from the ground. A detailed analysis of the source properties is given in accompanying papers. We have also performed an extensive series of simulations to investigate the errors in VSOP images caused by the relatively large holes in the (u,v)-plane when sources are observed near the orbit normal direction. We find that while the nominal dynamic range (defined as the ratio of map peak to off-source error) often exceeds 1000:1, the true dynamic range (map peak to on-source error) is only about 30:1 for relatively complex core-jet sources. For sources dominated by a strong point source, this value rises to approximately 100:1. We find the true dynamic range to be a relatively weak function of the difference in position angle (P.A.) between the jet P.A. and u-v coverage major axis P.A. For regions with low signal-to-noise ratios, typically located down the jet away from the core, large errors can occur, causing spurious features in VSOP images that should be interpreted with caution.

Generalised optical differentiation wavefront sensor: a sensitive high dynamic range wavefront sensor.

PubMed

Haffert, S Y

2016-08-22

Current wavefront sensors for high resolution imaging have either a large dynamic range or a high sensitivity. A new kind of wavefront sensor is developed which can have both: the Generalised Optical Differentiation wavefront sensor. This new wavefront sensor is based on the principles of optical differentiation by amplitude filters. We have extended the theory behind linear optical differentiation and generalised it to nonlinear filters. We used numerical simulations and laboratory experiments to investigate the properties of the generalised wavefront sensor. With this we created a new filter that can decouple the dynamic range from the sensitivity. These properties make it suitable for adaptive optic systems where a large range of phase aberrations have to be measured with high precision.

The Multidimensional Integrated Intelligent Imaging project (MI-3)

NASA Astrophysics Data System (ADS)

Allinson, N.; Anaxagoras, T.; Aveyard, J.; Arvanitis, C.; Bates, R.; Blue, A.; Bohndiek, S.; Cabello, J.; Chen, L.; Chen, S.; Clark, A.; Clayton, C.; Cook, E.; Cossins, A.; Crooks, J.; El-Gomati, M.; Evans, P. M.; Faruqi, W.; French, M.; Gow, J.; Greenshaw, T.; Greig, T.; Guerrini, N.; Harris, E. J.; Henderson, R.; Holland, A.; Jeyasundra, G.; Karadaglic, D.; Konstantinidis, A.; Liang, H. X.; Maini, K. M. S.; McMullen, G.; Olivo, A.; O'Shea, V.; Osmond, J.; Ott, R. J.; Prydderch, M.; Qiang, L.; Riley, G.; Royle, G.; Segneri, G.; Speller, R.; Symonds-Tayler, J. R. N.; Triger, S.; Turchetta, R.; Venanzi, C.; Wells, K.; Zha, X.; Zin, H.

2009-06-01

MI-3 is a consortium of 11 universities and research laboratories whose mission is to develop complementary metal-oxide semiconductor (CMOS) active pixel sensors (APS) and to apply these sensors to a range of imaging challenges. A range of sensors has been developed: On-Pixel Intelligent CMOS (OPIC)—designed for in-pixel intelligence; FPN—designed to develop novel techniques for reducing fixed pattern noise; HDR—designed to develop novel techniques for increasing dynamic range; Vanilla/PEAPS—with digital and analogue modes and regions of interest, which has also been back-thinned; Large Area Sensor (LAS)—a novel, stitched LAS; and eLeNA—which develops a range of low noise pixels. Applications being developed include autoradiography, a gamma camera system, radiotherapy verification, tissue diffraction imaging, X-ray phase-contrast imaging, DNA sequencing and electron microscopy.

High dynamic range bio-molecular ion microscopy with the Timepix detector.

PubMed

Jungmann, Julia H; MacAleese, Luke; Visser, Jan; Vrakking, Marc J J; Heeren, Ron M A

2011-10-15

Highly parallel, active pixel detectors enable novel detection capabilities for large biomolecules in time-of-flight (TOF) based mass spectrometry imaging (MSI). In this work, a 512 × 512 pixel, bare Timepix assembly combined with chevron microchannel plates (MCP) captures time-resolved images of several m/z species in a single measurement. Mass-resolved ion images from Timepix measurements of peptide and protein standards demonstrate the capability to return both mass-spectral and localization information of biologically relevant analytes from matrix-assisted laser desorption ionization (MALDI) on a commercial ion microscope. The use of a MCP-Timepix assembly delivers an increased dynamic range of several orders of magnitude. The Timepix returns defined mass spectra already at subsaturation MCP gains, which prolongs the MCP lifetime and allows the gain to be optimized for image quality. The Timepix peak resolution is only limited by the resolution of the in-pixel measurement clock. Oligomers of the protein ubiquitin were measured up to 78 kDa. © 2011 American Chemical Society

The JPEG XT suite of standards: status and future plans

NASA Astrophysics Data System (ADS)

Richter, Thomas; Bruylants, Tim; Schelkens, Peter; Ebrahimi, Touradj

2015-09-01

The JPEG standard has known an enormous market adoption. Daily, billions of pictures are created, stored and exchanged in this format. The JPEG committee acknowledges this success and spends continued efforts in maintaining and expanding the standard specifications. JPEG XT is a standardization effort targeting the extension of the JPEG features by enabling support for high dynamic range imaging, lossless and near-lossless coding, and alpha channel coding, while also guaranteeing backward and forward compatibility with the JPEG legacy format. This paper gives an overview of the current status of the JPEG XT standards suite. It discusses the JPEG legacy specification, and details how higher dynamic range support is facilitated both for integer and floating-point color representations. The paper shows how JPEG XT's support for lossless and near-lossless coding of low and high dynamic range images is achieved in combination with backward compatibility to JPEG legacy. In addition, the extensible boxed-based JPEG XT file format on which all following and future extensions of JPEG will be based is introduced. This paper also details how the lossy and lossless representations of alpha channels are supported to allow coding transparency information and arbitrarily shaped images. Finally, we conclude by giving prospects on upcoming JPEG standardization initiative JPEG Privacy & Security, and a number of other possible extensions in JPEG XT.

Imaging and full-length biometry of the eye during accommodation using spectral domain OCT with an optical switch

PubMed Central

Ruggeri, Marco; Uhlhorn, Stephen R.; De Freitas, Carolina; Ho, Arthur; Manns, Fabrice; Parel, Jean-Marie

2012-01-01

Abstract: An optical switch was implemented in the reference arm of an extended depth SD-OCT system to sequentially acquire OCT images at different depths into the eye ranging from the cornea to the retina. A custom-made accommodation module was coupled with the delivery of the OCT system to provide controlled step stimuli of accommodation and disaccommodation that preserve ocular alignment. The changes in the lens shape were imaged and ocular distances were dynamically measured during accommodation and disaccommodation. The system is capable of dynamic in vivo imaging of the entire anterior segment and eye-length measurement during accommodation in real-time. PMID:22808424

Imaging and full-length biometry of the eye during accommodation using spectral domain OCT with an optical switch.

PubMed

Ruggeri, Marco; Uhlhorn, Stephen R; De Freitas, Carolina; Ho, Arthur; Manns, Fabrice; Parel, Jean-Marie

2012-07-01

An optical switch was implemented in the reference arm of an extended depth SD-OCT system to sequentially acquire OCT images at different depths into the eye ranging from the cornea to the retina. A custom-made accommodation module was coupled with the delivery of the OCT system to provide controlled step stimuli of accommodation and disaccommodation that preserve ocular alignment. The changes in the lens shape were imaged and ocular distances were dynamically measured during accommodation and disaccommodation. The system is capable of dynamic in vivo imaging of the entire anterior segment and eye-length measurement during accommodation in real-time.

Multi-dynamic range compressional wave detection using optical-frequency comb

NASA Astrophysics Data System (ADS)

Minamikawa, Takeo; Masuoka, Takashi; Oe, Ryo; Nakajima, Yoshiaki; Yamaoka, Yoshihisa; Minoshima, Kaoru; Yasui, Takeshi

2018-02-01

Compressional wave detection is useful means for health monitoring of building, detection of abnormal vibration of moving objects, defect evaluation, and biomedical imaging such as echography and photoacoustic imaging. The frequency of the compressional wave is varied from quasi-static to a few tens of megahertz depending on applications. Since the dynamic range of general compressional wave detectors is limited, we need to choose a proper compressional wave detector depending on applications. For the compressional wave detection with wide dynamic range, two or more detectors with different detection ranges is required. However, these detectors with different detection ranges generally has different accuracy and precision, disabling the seamless detection over these detection ranges. In this study, we proposed a compressional wave detector employing optical frequency comb (OFC). The compressional wave was sensed with a part of an OFC cavity, being encoded into OFC. The spectrally encoded OFC was converted to radio-frequency by the frequency link nature of OFC. The compressional wave-encoded radio-frequency can therefore be directly measured with a high-speed photodetector. To enhance the dynamic range of the compressional wave detection, we developed a cavityfeedback-based system and a phase-sensitive detection system, both of which the accuracy and precision are coherently linked to these of the OFC. We provided a proof-of-principle demonstration of the detection of compressional wave from quasi-static to ultrasound wave by using the OFC-based compressional wave sensor. Our proposed approach will serve as a unique and powerful tool for detecting compressional wave versatile applications in the future.

Laser fluence dependence on emission dynamics of ultrafast laser induced copper plasma

DOE PAGES

Anoop, K. K.; Harilal, S. S.; Philip, Reji; ...

2016-11-14

The characteristic emission features of a laser-produced plasma strongly depend strongly on the laser fluence. We investigated the spatial and temporal dynamics of neutrals and ions in femtosecond laser (800 nm, ≈ 40 fs, Ti:Sapphire) induced copper plasma in vacuum using both optical emission spectroscopy (OES) and spectrally resolved two-dimensional (2D) imaging methods over a wide fluence range of 0.5 J/cm 2-77.5 J/cm 2. 2D fast gated monochromatic images showed distinct plume splitting between the neutral and ions especially at moderate to higher fluence ranges. OES studies at low to moderate laser fluence regime confirm intense neutral line emission overmore » the ion emission whereas this trend changes at higher laser fluence with dominance of the latter. This evidences a clear change in the physical processes involved in femtosecond laser matter interaction at high input laser intensity. The obtained ion dynamics resulting from the OES, and spectrally resolved 2D imaging are compared with charged particle measurement employing Faraday cup and Langmuir probe and results showed good correlation.« less

The Focusing Optics X-ray Solar Imager

NASA Astrophysics Data System (ADS)

Glesener, Lindsay; Krucker, S.; Christe, S.; Turin, P.; McBride, S.

2009-01-01

The Focusing Optics X-ray Solar Imager (FOXSI) is a NASA Low Cost Access to Space sounding rocket payload scheduled to fly in late 2010 to observe hard X-ray emission (HXR) from the quiet Sun. Particle acceleration in small "nanoflares" in the quiet Sun is thought to play an important role in the heating of the corona to millions of degrees Kelvin. FOXSI HXR observations of these flares will provide first estimates of the non-thermal energy content in small flares from the quiet Sun. Imaging nanoflares requires high energy sensitivity and a large dynamic range. To date, the most sensitive HXR images are made using a rotating modulating collimator aboard the Reuven Ramaty High Energy Spectroscopic Imager satellite (RHESSI). However, the rotating modulation technique is intrinsically limited in sensitivity and dynamic range. The focusing optics of FOXSI will achieve a sensitivity 100 times better than that of RHESSI at energies around 10 keV. FOXSI uses nested-shell, grazing-angle optics and silicon strip detectors to achieve an angular resolution of 12" (FWHM) and 1 keV energy resolution. FOXSI will observe the quiet Sun in the 4 to 15 keV range for 5 minutes. The focusing optics technique developed by FOXSI will prove useful to future solar HXR observing missions, especially those interested in imaging faint HXR emission from particle acceleration regions in the corona.

The Astronomical Low Frequency Array: A Proposed Explorer Mission for Radio Astronomy

NASA Technical Reports Server (NTRS)

Jones, D.; Allen, R.; Basart, J.; Bastian, T.; Bougeret, J. L.; Dennison, B.; Desch, M.; Dwarakanath, K.; Erickson, W.; Finley, D.;

Phase retrieval by coherent modulation imaging.

PubMed

Zhang, Fucai; Chen, Bo; Morrison, Graeme R; Vila-Comamala, Joan; Guizar-Sicairos, Manuel; Robinson, Ian K

2016-11-18

Phase retrieval is a long-standing problem in imaging when only the intensity of the wavefield can be recorded. Coherent diffraction imaging is a lensless technique that uses iterative algorithms to recover amplitude and phase contrast images from diffraction intensity data. For general samples, phase retrieval from a single-diffraction pattern has been an algorithmic and experimental challenge. Here we report a method of phase retrieval that uses a known modulation of the sample exit wave. This coherent modulation imaging method removes inherent ambiguities of coherent diffraction imaging and uses a reliable, rapidly converging iterative algorithm involving three planes. It works for extended samples, does not require tight support for convergence and relaxes dynamic range requirements on the detector. Coherent modulation imaging provides a robust method for imaging in materials and biological science, while its single-shot capability will benefit the investigation of dynamical processes with pulsed sources, such as X-ray free-electron lasers.

Quantitative mass imaging of single biological macromolecules.

PubMed

Young, Gavin; Hundt, Nikolas; Cole, Daniel; Fineberg, Adam; Andrecka, Joanna; Tyler, Andrew; Olerinyova, Anna; Ansari, Ayla; Marklund, Erik G; Collier, Miranda P; Chandler, Shane A; Tkachenko, Olga; Allen, Joel; Crispin, Max; Billington, Neil; Takagi, Yasuharu; Sellers, James R; Eichmann, Cédric; Selenko, Philipp; Frey, Lukas; Riek, Roland; Galpin, Martin R; Struwe, Weston B; Benesch, Justin L P; Kukura, Philipp

2018-04-27

The cellular processes underpinning life are orchestrated by proteins and their interactions. The associated structural and dynamic heterogeneity, despite being key to function, poses a fundamental challenge to existing analytical and structural methodologies. We used interferometric scattering microscopy to quantify the mass of single biomolecules in solution with 2% sequence mass accuracy, up to 19-kilodalton resolution, and 1-kilodalton precision. We resolved oligomeric distributions at high dynamic range, detected small-molecule binding, and mass-imaged proteins with associated lipids and sugars. These capabilities enabled us to characterize the molecular dynamics of processes as diverse as glycoprotein cross-linking, amyloidogenic protein aggregation, and actin polymerization. Interferometric scattering mass spectrometry allows spatiotemporally resolved measurement of a broad range of biomolecular interactions, one molecule at a time. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

High order magnetic optics for high dynamic range proton radiography at a kinetic energy 800 MeV

DOE PAGES

Sjue, Sky K. L.; Morris, Christopher L.; Merrill, Frank Edward; ...

2016-01-14

Flash radiography with 800 MeV kinetic energy protons at Los Alamos National Laboratory is an important experimental tool for investigations of dynamic material behavior driven by high explosives or pulsed power. The extraction of quantitative information about density fields in a dynamic experiment from proton generated images requires a high fidelity model of the protonimaging process. It is shown that accurate calculations of the transmission through the magnetic lens system require terms beyond second order for protons far from the tune energy. The approach used integrates the correlated multiple Coulomb scattering distribution simultaneously over the collimator and the image plane.more » Furthermore, comparison with a series of static calibrationimages demonstrates the model’s accurate reproduction of both the transmission and blur over a wide range of tune energies in an inverse identity lens that consists of four quadrupole electromagnets.« less

Effects of Scene Modulation Image Blur and Noise Upon Human Target Acquisition Performance.

DTIC Science & Technology

1997-06-01

AFRL-HE-WP-TR-1998-0012 UNITED STATES AIR FORCE RESEARCH LABORATORY EFFECTS OF SCENE MODULATION IMAGE BLUR AND NOISE UPON HUMAN TARGET...COVERED INTERIM (July 1996 - August 1996) TITLE AND SUBTITLE Effects of Scene Modulation Image Blur and Noise Upon Human Target Acquisition...dilemma in image transmission and display is that we must compromise between die conflicting constraints of dynamic range and noise . Three target

High dynamic range fringe acquisition: A novel 3-D scanning technique for high-reflective surfaces

NASA Astrophysics Data System (ADS)

Jiang, Hongzhi; Zhao, Huijie; Li, Xudong

2012-10-01

This paper presents a novel 3-D scanning technique for high-reflective surfaces based on phase-shifting fringe projection method. High dynamic range fringe acquisition (HDRFA) technique is developed to process the fringe images reflected from the shiny surfaces, and generates a synthetic fringe image by fusing the raw fringe patterns, acquired with different camera exposure time and the illumination fringe intensity from the projector. Fringe image fusion algorithm is introduced to avoid saturation and under-illumination phenomenon by choosing the pixels in the raw fringes with the highest fringe modulation intensity. A method of auto-selection of HDRFA parameters is developed and largely increases the measurement automation. The synthetic fringes have higher signal-to-noise ratio (SNR) under ambient light by optimizing HDRFA parameters. Experimental results show that the proposed technique can successfully measure objects with high-reflective surfaces and is insensitive to ambient light.

Soft X-ray spectromicroscopy using ptychography with randomly phased illumination

NASA Astrophysics Data System (ADS)

Maiden, A. M.; Morrison, G. R.; Kaulich, B.; Gianoncelli, A.; Rodenburg, J. M.

2013-04-01

Ptychography is a form of scanning diffractive imaging that can successfully retrieve the modulus and phase of both the sample transmission function and the illuminating probe. An experimental difficulty commonly encountered in diffractive imaging is the large dynamic range of the diffraction data. Here we report a novel ptychographic experiment using a randomly phased X-ray probe to considerably reduce the dynamic range of the recorded diffraction patterns. Images can be reconstructed reliably and robustly from this setup, even when scatter from the specimen is weak. A series of ptychographic reconstructions at X-ray energies around the L absorption edge of iron demonstrates the advantages of this method for soft X-ray spectromicroscopy, which can readily provide chemical sensitivity without the need for optical refocusing. In particular, the phase signal is in perfect registration with the modulus signal and provides complementary information that can be more sensitive to changes in the local chemical environment.

Improvements on Fresnel arrays for high contrast imaging

NASA Astrophysics Data System (ADS)

Wilhem, Roux; Laurent, Koechlin

2018-03-01

The Fresnel Diffractive Array Imager (FDAI) is based on a new optical concept for space telescopes, developed at Institut de Recherche en Astrophysique et Planétologie (IRAP), Toulouse, France. For the visible and near-infrared it has already proven its performances in resolution and dynamic range. We propose it now for astrophysical applications in the ultraviolet with apertures from 6 to 30 meters, aimed at imaging in UV faint astrophysical sources close to bright ones, as well as other applications requiring high dynamic range. Of course the project needs first a probatory mission at small aperture to validate the concept in space. In collaboration with institutes in Spain and Russia, we will propose to board a small prototype of Fresnel imager on the International Space Station (ISS), with a program combining technical tests and astrophysical targets. The spectral domain should contain the Lyman- α line ( λ = 121 nm). As part of its preparation, we improve the Fresnel array design for a better Point Spread Function in UV, presently on a small laboratory prototype working at 260 nm. Moreover, we plan to validate a new optical design and chromatic correction adapted to UV. In this article we present the results of numerical propagations showing the improvement in dynamic range obtained by combining and adapting three methods : central obturation, optimization of the bars mesh holding the Fresnel rings, and orthogonal apodization. We briefly present the proposed astrophysical program of a probatory mission with such UV optics.

Cardiovascular and pulmonary dynamics by quantitative imaging

NASA Technical Reports Server (NTRS)

Wood, E. H.

1976-01-01

The accuracy and range of studies on cardiovascular and pulmonary functions can be greatly facilitated if the motions of the underlying organ systems throughout individual cycles can be directly visualized and readily measured with minimum or preferably no effect on these motions. Achievement of this objective requires development of techniques for quantitative noninvasive or minimally invasive dynamic and stop-action imaging of the organ systems. A review of advances in dynamic quantitative imaging of moving organs reveals that the revolutionary value of cross-sectional and three-dimensional images produced by various types of radiant energy such as X-rays and gamma rays, positrons, electrons, protons, light, and ultrasound for clinical diagnostic and biomedical research applications is just beginning to be realized. The fabrication of a clinically useful cross-section reconstruction device with sensing capabilities for both anatomical structural composition and chemical composition may be possible and awaits future development.

Reproducibility of dynamically represented acoustic lung images from healthy individuals

PubMed Central

Maher, T M; Gat, M; Allen, D; Devaraj, A; Wells, A U; Geddes, D M

2008-01-01

Background and aim: Acoustic lung imaging offers a unique method for visualising the lung. This study was designed to demonstrate reproducibility of acoustic lung images recorded from healthy individuals at different time points and to assess intra- and inter-rater agreement in the assessment of dynamically represented acoustic lung images. Methods: Recordings from 29 healthy volunteers were made on three separate occasions using vibration response imaging. Reproducibility was measured using quantitative, computerised assessment of vibration energy. Dynamically represented acoustic lung images were scored by six blinded raters. Results: Quantitative measurement of acoustic recordings was highly reproducible with an intraclass correlation score of 0.86 (very good agreement). Intraclass correlations for inter-rater agreement and reproducibility were 0.61 (good agreement) and 0.86 (very good agreement), respectively. There was no significant difference found between the six raters at any time point. Raters ranged from 88% to 95% in their ability to identically evaluate the different features of the same image presented to them blinded on two separate occasions. Conclusion: Acoustic lung imaging is reproducible in healthy individuals. Graphic representation of lung images can be interpreted with a high degree of accuracy by the same and by different reviewers. PMID:18024534

Establishing imaging sensor specifications for digital still cameras

NASA Astrophysics Data System (ADS)

Kriss, Michael A.

2007-02-01

Digital Still Cameras, DSCs, have now displaced conventional still cameras in most markets. The heart of a DSC is thought to be the imaging sensor, be it Full Frame CCD, and Interline CCD, a CMOS sensor or the newer Foveon buried photodiode sensors. There is a strong tendency by consumers to consider only the number of mega-pixels in a camera and not to consider the overall performance of the imaging system, including sharpness, artifact control, noise, color reproduction, exposure latitude and dynamic range. This paper will provide a systematic method to characterize the physical requirements of an imaging sensor and supporting system components based on the desired usage. The analysis is based on two software programs that determine the "sharpness", potential for artifacts, sensor "photographic speed", dynamic range and exposure latitude based on the physical nature of the imaging optics, sensor characteristics (including size of pixels, sensor architecture, noise characteristics, surface states that cause dark current, quantum efficiency, effective MTF, and the intrinsic full well capacity in terms of electrons per square centimeter). Examples will be given for consumer, pro-consumer, and professional camera systems. Where possible, these results will be compared to imaging system currently on the market.

Dynamic Environmental Photosynthetic Imaging Reveals Emergent Phenotypes

DOE PAGES

Cruz, Jeffrey A.; Savage, Linda J.; Zegarac, Robert; ...

2016-06-22

Understanding and improving the productivity and robustness of plant photosynthesis requires high-throughput phenotyping under environmental conditions that are relevant to the field. Here we demonstrate the dynamic environmental photosynthesis imager (DEPI), an experimental platform for integrated, continuous, and high-throughput measurements of photosynthetic parameters during plant growth under reproducible yet dynamic environmental conditions. Using parallel imagers obviates the need to move plants or sensors, reducing artifacts and allowing simultaneous measurement on large numbers of plants. As a result, DEPI can reveal phenotypes that are not evident under standard laboratory conditions but emerge under progressively more dynamic illumination. We show examples inmore » mutants of Arabidopsis of such “emergent phenotypes” that are highly transient and heterogeneous, appearing in different leaves under different conditions and depending in complex ways on both environmental conditions and plant developmental age. Finally, these emergent phenotypes appear to be caused by a range of phenomena, suggesting that such previously unseen processes are critical for plant responses to dynamic environments.« less

Clinical Applications of a CT Window Blending Algorithm: RADIO (Relative Attenuation-Dependent Image Overlay).

PubMed

Mandell, Jacob C; Khurana, Bharti; Folio, Les R; Hyun, Hyewon; Smith, Stacy E; Dunne, Ruth M; Andriole, Katherine P

2017-06-01

A methodology is described using Adobe Photoshop and Adobe Extendscript to process DICOM images with a Relative Attenuation-Dependent Image Overlay (RADIO) algorithm to visualize the full dynamic range of CT in one view, without requiring a change in window and level settings. The potential clinical uses for such an algorithm are described in a pictorial overview, including applications in emergency radiology, oncologic imaging, and nuclear medicine and molecular imaging.

On the relationships between higher and lower bit-depth system measurements

NASA Astrophysics Data System (ADS)

Burks, Stephen D.; Haefner, David P.; Doe, Joshua M.

2018-04-01

The quality of an imaging system can be assessed through controlled laboratory objective measurements. Currently, all imaging measurements require some form of digitization in order to evaluate a metric. Depending on the device, the amount of bits available, relative to a fixed dynamic range, will exhibit quantization artifacts. From a measurement standpoint, measurements are desired to be performed at the highest possible bit-depth available. In this correspondence, we described the relationship between higher and lower bit-depth measurements. The limits to which quantization alters the observed measurements will be presented. Specifically, we address dynamic range, MTF, SiTF, and noise. Our results provide guidelines to how systems of lower bit-depth should be characterized and the corresponding experimental methods.

Electrically optofluidic zoom system with a large zoom range and high-resolution image.

PubMed

Li, Lei; Yuan, Rong-Ying; Wang, Jin-Hui; Wang, Qiong-Hua

2017-09-18

We report an electrically controlled optofluidic zoom system which can achieve a large continuous zoom change and high-resolution image. The zoom system consists of an optofluidic zoom objective and a switchable light path which are controlled by two liquid optical shutters. The proposed zoom system can achieve a large tunable focal length range from 36mm to 92mm. And in this tuning range, the zoom system can correct aberrations dynamically, thus the image resolution is high. Due to large zoom range, the proposed imaging system incorporates both camera configuration and telescope configuration into one system. In addition, the whole system is electrically controlled by three electrowetting liquid lenses and two liquid optical shutters, therefore, the proposed system is very compact and free of mechanical moving parts. The proposed zoom system has potential to take place of conventional zoom systems.

Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics.

PubMed

He, Bin; Sohrabpour, Abbas; Brown, Emery; Liu, Zhongming

2018-06-04

Brain activity and connectivity are distributed in the three-dimensional space and evolve in time. It is important to image brain dynamics with high spatial and temporal resolution. Electroencephalography (EEG) and magnetoencephalography (MEG) are noninvasive measurements associated with complex neural activations and interactions that encode brain functions. Electrophysiological source imaging estimates the underlying brain electrical sources from EEG and MEG measurements. It offers increasingly improved spatial resolution and intrinsically high temporal resolution for imaging large-scale brain activity and connectivity on a wide range of timescales. Integration of electrophysiological source imaging and functional magnetic resonance imaging could further enhance spatiotemporal resolution and specificity to an extent that is not attainable with either technique alone. We review methodological developments in electrophysiological source imaging over the past three decades and envision its future advancement into a powerful functional neuroimaging technology for basic and clinical neuroscience applications.

Low-power low-noise mixed-mode VLSI ASIC for infinite dynamic range imaging applications

NASA Astrophysics Data System (ADS)

Turchetta, Renato; Hu, Y.; Zinzius, Y.; Colledani, C.; Loge, A.

1998-11-01

Solid state solutions for imaging are mainly represented by CCDs and, more recently, by CMOS imagers. Both devices are based on the integration of the total charge generated by the impinging radiation, with no processing of the single photon information. The dynamic range of these devices is intrinsically limited by the finite value of noise. Here we present the design of an architecture which allows efficient, in-pixel, noise reduction to a practically zero level, thus allowing infinite dynamic range imaging. A detailed calculation of the dynamic range is worked out, showing that noise is efficiently suppressed. This architecture is based on the concept of single-photon counting. In each pixel, we integrate both the front-end, low-noise, low-power analog part and the digital part. The former consists of a charge preamplifier, an active filter for optimal noise bandwidth reduction, a buffer and a threshold comparator, and the latter is simply a counter, which can be programmed to act as a normal shift register for the readout of the counters' contents. Two different ASIC's based on this concept have been designed for different applications. The first one has been optimized for silicon edge-on microstrips detectors, used in a digital mammography R and D project. It is a 32-channel circuit, with a 16-bit binary static counter.It has been optimized for a relatively large detector capacitance of 5 pF. Noise has been measured to be equal to 100 + 7*Cd (pF) electron rms with the digital part, showing no degradation of the noise performances with respect to the design values. The power consumption is 3.8mW/channel for a peaking time of about 1 microsecond(s) . The second circuit is a prototype for pixel imaging. The total active area is about (250 micrometers )**2. The main differences of the electronic architecture with respect to the first prototype are: i) different optimization of the analog front-end part for low-capacitance detectors, ii) in- pixel 4-bit comparator-offset compensation, iii) 15-bit pseudo-random counter. The power consumption is 255 (mu) W/channel for a peaking time of 300 ns and an equivalent noise charge of 185 + 97*Cd electrons rms. Simulation and experimental result as well as imaging results will be presented.

Signal enhancement in optical projection tomography via virtual high dynamic range imaging of single exposure

NASA Astrophysics Data System (ADS)

Yang, Yujie; Dong, Di; Shi, Liangliang; Wang, Jun; Yang, Xin; Tian, Jie

2015-03-01

Optical projection tomography (OPT) is a mesoscopic scale optical imaging technique for specimens between 1mm and 10mm. OPT has been proven to be immensely useful in a wide variety of biological applications, such as developmental biology and pathology, but its shortcomings in imaging specimens containing widely differing contrast elements are obvious. The longer exposure for high intensity tissues may lead to over saturation of other areas, whereas a relatively short exposure may cause similarity with surrounding background. In this paper, we propose an approach to make a trade-off between capturing weak signals and revealing more details for OPT imaging. This approach consists of three steps. Firstly, the specimens are merely scanned in 360 degrees above a normal exposure but non-overexposure to acquire the projection data. This reduces the photo bleaching and pre-registration computation compared with multiple different exposures in conventional high dynamic range (HDR) imaging method. Secondly, three virtual channels are produced for each projection image based on the histogram distribution to simulate the low, normal and high exposure images used in the traditional HDR technology in photography. Finally, each virtual channel is normalized to the full gray scale range and three channels are recombined into one image using weighting coefficients optimized by a standard eigen-decomposition method. After applying our approach on the projection data, filtered back projection (FBP) algorithm is carried out for 3-dimentional reconstruction. The neonatal wild-type mouse paw has been scanned to verify this approach. Results demonstrated the effectiveness of the proposed approach.

Performance of an extended dynamic range time delay integration charge coupled device (XDR TDI CCD) for high-intrascene dynamic range scanning

NASA Astrophysics Data System (ADS)

Levine, Peter A.; Dawson, Robin M.; Andrews, James T.; Bhaskaran, Mahalingham; Furst, David; Hsueh, Fu-Lung; Meray, Grazyna M.; Sudol, Thomas M.; Swain, Pradyumna K.; Tower, John R.

2003-05-01

Many applications, such as industrial inspection and overhead reconnaissance benefit from line scanning architectures where time delay integration (TDI) significantly improves sensitivity. CCDs are particularly well suited to the TDI architecture since charge is transferred virtually noiselessly down the column. Sarnoff's TDI CCDs have demonstrated extremely high speeds where a 7200 x 64, 8 um pixel device with 120 output ports demonstrated a vertical line transfer rate greater than 800 kHz. The most recent addition to Sarnoff's TDI technology is the implementation of extended dynamic range (XDR) in high speed, back illuminated TDI CCDs. The optical, intrascene dynamic range can be adjusted in the design of the imager with measured dynamic ranges exceeding 2,000,000:1 with no degradation in low light performance. The device provides a piecewise linear response to light where multiple slopes and break points can be set during the CCD design. A description of the device architecture and measured results from fabricated XDR TDI CCDs are presented.

Dynamic whole-body PET parametric imaging: I. Concept, acquisition protocol optimization and clinical application.

PubMed

Karakatsanis, Nicolas A; Lodge, Martin A; Tahari, Abdel K; Zhou, Y; Wahl, Richard L; Rahmim, Arman

2013-10-21

Static whole-body PET/CT, employing the standardized uptake value (SUV), is considered the standard clinical approach to diagnosis and treatment response monitoring for a wide range of oncologic malignancies. Alternative PET protocols involving dynamic acquisition of temporal images have been implemented in the research setting, allowing quantification of tracer dynamics, an important capability for tumor characterization and treatment response monitoring. Nonetheless, dynamic protocols have been confined to single-bed-coverage limiting the axial field-of-view to ~15-20 cm, and have not been translated to the routine clinical context of whole-body PET imaging for the inspection of disseminated disease. Here, we pursue a transition to dynamic whole-body PET parametric imaging, by presenting, within a unified framework, clinically feasible multi-bed dynamic PET acquisition protocols and parametric imaging methods. We investigate solutions to address the challenges of: (i) long acquisitions, (ii) small number of dynamic frames per bed, and (iii) non-invasive quantification of kinetics in the plasma. In the present study, a novel dynamic (4D) whole-body PET acquisition protocol of ~45 min total length is presented, composed of (i) an initial 6 min dynamic PET scan (24 frames) over the heart, followed by (ii) a sequence of multi-pass multi-bed PET scans (six passes × seven bed positions, each scanned for 45 s). Standard Patlak linear graphical analysis modeling was employed, coupled with image-derived plasma input function measurements. Ordinary least squares Patlak estimation was used as the baseline regression method to quantify the physiological parameters of tracer uptake rate Ki and total blood distribution volume V on an individual voxel basis. Extensive Monte Carlo simulation studies, using a wide set of published kinetic FDG parameters and GATE and XCAT platforms, were conducted to optimize the acquisition protocol from a range of ten different clinically acceptable sampling schedules examined. The framework was also applied to six FDG PET patient studies, demonstrating clinical feasibility. Both simulated and clinical results indicated enhanced contrast-to-noise ratios (CNRs) for Ki images in tumor regions with notable background FDG concentration, such as the liver, where SUV performed relatively poorly. Overall, the proposed framework enables enhanced quantification of physiological parameters across the whole body. In addition, the total acquisition length can be reduced from 45 to ~35 min and still achieve improved or equivalent CNR compared to SUV, provided the true Ki contrast is sufficiently high. In the follow-up companion paper, a set of advanced linear regression schemes is presented to particularly address the presence of noise, and attempt to achieve a better trade-off between the mean-squared error and the CNR metrics, resulting in enhanced task-based imaging.

Dynamic whole body PET parametric imaging: I. Concept, acquisition protocol optimization and clinical application

PubMed Central

Karakatsanis, Nicolas A.; Lodge, Martin A.; Tahari, Abdel K.; Zhou, Y.; Wahl, Richard L.; Rahmim, Arman

2013-01-01

Static whole body PET/CT, employing the standardized uptake value (SUV), is considered the standard clinical approach to diagnosis and treatment response monitoring for a wide range of oncologic malignancies. Alternative PET protocols involving dynamic acquisition of temporal images have been implemented in the research setting, allowing quantification of tracer dynamics, an important capability for tumor characterization and treatment response monitoring. Nonetheless, dynamic protocols have been confined to single bed-coverage limiting the axial field-of-view to ~15–20 cm, and have not been translated to the routine clinical context of whole-body PET imaging for the inspection of disseminated disease. Here, we pursue a transition to dynamic whole body PET parametric imaging, by presenting, within a unified framework, clinically feasible multi-bed dynamic PET acquisition protocols and parametric imaging methods. We investigate solutions to address the challenges of: (i) long acquisitions, (ii) small number of dynamic frames per bed, and (iii) non-invasive quantification of kinetics in the plasma. In the present study, a novel dynamic (4D) whole body PET acquisition protocol of ~45min total length is presented, composed of (i) an initial 6-min dynamic PET scan (24 frames) over the heart, followed by (ii) a sequence of multi-pass multi-bed PET scans (6 passes x 7 bed positions, each scanned for 45sec). Standard Patlak linear graphical analysis modeling was employed, coupled with image-derived plasma input function measurements. Ordinary least squares (OLS) Patlak estimation was used as the baseline regression method to quantify the physiological parameters of tracer uptake rate Ki and total blood distribution volume V on an individual voxel basis. Extensive Monte Carlo simulation studies, using a wide set of published kinetic FDG parameters and GATE and XCAT platforms, were conducted to optimize the acquisition protocol from a range of 10 different clinically acceptable sampling schedules examined. The framework was also applied to six FDG PET patient studies, demonstrating clinical feasibility. Both simulated and clinical results indicated enhanced contrast-to-noise ratios (CNRs) for Ki images in tumor regions with notable background FDG concentration, such as the liver, where SUV performed relatively poorly. Overall, the proposed framework enables enhanced quantification of physiological parameters across the whole-body. In addition, the total acquisition length can be reduced from 45min to ~35min and still achieve improved or equivalent CNR compared to SUV, provided the true Ki contrast is sufficiently high. In the follow-up companion paper, a set of advanced linear regression schemes is presented to particularly address the presence of noise, and attempt to achieve a better trade-off between the mean-squared error (MSE) and the CNR metrics, resulting in enhanced task-based imaging. PMID:24080962

Dynamic whole-body PET parametric imaging: I. Concept, acquisition protocol optimization and clinical application

NASA Astrophysics Data System (ADS)

Karakatsanis, Nicolas A.; Lodge, Martin A.; Tahari, Abdel K.; Zhou, Y.; Wahl, Richard L.; Rahmim, Arman

2013-10-01

Static whole-body PET/CT, employing the standardized uptake value (SUV), is considered the standard clinical approach to diagnosis and treatment response monitoring for a wide range of oncologic malignancies. Alternative PET protocols involving dynamic acquisition of temporal images have been implemented in the research setting, allowing quantification of tracer dynamics, an important capability for tumor characterization and treatment response monitoring. Nonetheless, dynamic protocols have been confined to single-bed-coverage limiting the axial field-of-view to ˜15-20 cm, and have not been translated to the routine clinical context of whole-body PET imaging for the inspection of disseminated disease. Here, we pursue a transition to dynamic whole-body PET parametric imaging, by presenting, within a unified framework, clinically feasible multi-bed dynamic PET acquisition protocols and parametric imaging methods. We investigate solutions to address the challenges of: (i) long acquisitions, (ii) small number of dynamic frames per bed, and (iii) non-invasive quantification of kinetics in the plasma. In the present study, a novel dynamic (4D) whole-body PET acquisition protocol of ˜45 min total length is presented, composed of (i) an initial 6 min dynamic PET scan (24 frames) over the heart, followed by (ii) a sequence of multi-pass multi-bed PET scans (six passes × seven bed positions, each scanned for 45 s). Standard Patlak linear graphical analysis modeling was employed, coupled with image-derived plasma input function measurements. Ordinary least squares Patlak estimation was used as the baseline regression method to quantify the physiological parameters of tracer uptake rate Ki and total blood distribution volume V on an individual voxel basis. Extensive Monte Carlo simulation studies, using a wide set of published kinetic FDG parameters and GATE and XCAT platforms, were conducted to optimize the acquisition protocol from a range of ten different clinically acceptable sampling schedules examined. The framework was also applied to six FDG PET patient studies, demonstrating clinical feasibility. Both simulated and clinical results indicated enhanced contrast-to-noise ratios (CNRs) for Ki images in tumor regions with notable background FDG concentration, such as the liver, where SUV performed relatively poorly. Overall, the proposed framework enables enhanced quantification of physiological parameters across the whole body. In addition, the total acquisition length can be reduced from 45 to ˜35 min and still achieve improved or equivalent CNR compared to SUV, provided the true Ki contrast is sufficiently high. In the follow-up companion paper, a set of advanced linear regression schemes is presented to particularly address the presence of noise, and attempt to achieve a better trade-off between the mean-squared error and the CNR metrics, resulting in enhanced task-based imaging.

Assessing Mesoscale Material Response via High-Resolution Line-Imaging VISAR

NASA Astrophysics Data System (ADS)

Furnish, M. D.; Trott, W. M.; Mason, J.; Podsednik, J.; Reinhart, W. D.; Hall, C.

2004-07-01

Of special promise for providing dynamic mesoscale response data is the line-imaging VISAR, an instrument for providing spatially resolved velocity histories in dynamic experiments. We have prepared a line-imaging VISAR system capable of spatial resolution in the 10 - 20 micron range. We are applying this instrument to selected experiments on a compressed gas gun, chosen to provide initial data for several problems of interest, including: (1) pore-collapse in single-crystal copper (70 micron diameter hole; 2 different versions); and (2) response of a welded joint in dissimilar materials (Ta, Nb) to ramp loading relative to that of a compression joint.

Dynamic full field OCT: metabolic contrast at subcellular level (Conference Presentation)

NASA Astrophysics Data System (ADS)

Apelian, Clement; Harms, Fabrice; Thouvenin, Olivier; Boccara, Claude A.

2016-03-01

Cells shape or density is an important marker of tissues pathology. However, individual cells are difficult to observe in thick tissues frequently presenting highly scattering structures such as collagen fibers. Endogenous techniques struggle to image cells in these conditions. Moreover, exogenous contrast agents like dyes, fluorophores or nanoparticles cannot always be used, especially if non-invasive imaging is required. Scatterers motion happening down to the millisecond scale, much faster than the still and highly scattering structures (global motion of the tissue), allowed us to develop a new approach based on the time dependence of the FF-OCT signals. This method reveals hidden cells after a spatiotemporal analysis based on singular value decomposition and wavelet analysis concepts. It does also give us access to local dynamics of imaged scatterers. This dynamic information is linked with the local metabolic activity that drives these scatterers. Our technique can explore subcellular scales with micrometric resolution and dynamics ranging from the millisecond to seconds. By this mean we studied a wide range of tissues, animal and human in both normal and pathological conditions (cancer, ischemia, osmotic shock…) in different organs such as liver, kidney, and brain among others. Different cells, undetectable with FF-OCT, were identified (erythrocytes, hepatocytes…). Different scatterers clusters express different characteristic times and thus can be related to different mechanisms that we identify with metabolic functions. We are confident that the D-FFOCT, by accessing to a new spatiotemporal metabolic contrast, will be a leading technique on tissue imaging and for better medical diagnosis.

Image plates as x-ray detectors in plasma physics experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gales, S.G.; Bentley, C.D.

2004-10-01

The performance of image plates based on the photostimulable phosphor BaF(Br,l):Eu{sup 2+} has been investigated and compared with x-ray film. Evaluation of detective quantum efficiency (DQE), sensitivity, dynamic range, and linearity was carried out for several types of commercially available image plate, using the Excalibur soft x-ray calibration facility at AWE. Image plate response was found to be linear over a dynamic range of 5 orders of magnitude. One type of image plate was found to have a number of advantages for soft x-ray detection, with a measured sensitivity 1 order of magnitude greater than that of Kodak Industrex CXmore » and DEF-5 x-ray film. The DQE of this plate was found to be superior to that of film at low [less than 10{sup 3} photons/(50 {mu}m){sup 2}] and high fluxes [greater than 10{sup 4} photons/(50 {mu}m){sup 2}]. The spatial resolution of image plates, scanned with several models of commercial image plate readers, has been evaluated using a USAF resolution test target. The highest spatial resolution measured is 35 {mu}m. Though this is significantly lower than the resolution possible with film, it is sufficient for many applications. Image plates were fielded in a refractive x-ray lens imaging diagnostic on the 1 TW Helen laser and these results are discussed.« less

All-digital full waveform recording photon counting flash lidar

NASA Astrophysics Data System (ADS)

Grund, Christian J.; Harwit, Alex

2010-08-01

Current generation analog and photon counting flash lidar approaches suffer from limitation in waveform depth, dynamic range, sensitivity, false alarm rates, optical acceptance angle (f/#), optical and electronic cross talk, and pixel density. To address these issues Ball Aerospace is developing a new approach to flash lidar that employs direct coupling of a photocathode and microchannel plate front end to a high-speed, pipelined, all-digital Read Out Integrated Circuit (ROIC) to achieve photon-counting temporal waveform capture in each pixel on each laser return pulse. A unique characteristic is the absence of performance-limiting analog or mixed signal components. When implemented in 65nm CMOS technology, the Ball Intensified Imaging Photon Counting (I2PC) flash lidar FPA technology can record up to 300 photon arrivals in each pixel with 100 ps resolution on each photon return, with up to 6000 range bins in each pixel. The architecture supports near 100% fill factor and fast optical system designs (f/#<1), and array sizes to 3000×3000 pixels. Compared to existing technologies, >60 dB ultimate dynamic range improvement, and >104 reductions in false alarm rates are anticipated, while achieving single photon range precision better than 1cm. I2PC significantly extends long-range and low-power hard target imaging capabilities useful for autonomous hazard avoidance (ALHAT), navigation, imaging vibrometry, and inspection applications, and enables scannerless 3D imaging for distributed target applications such as range-resolved atmospheric remote sensing, vegetation canopies, and camouflage penetration from terrestrial, airborne, GEO, and LEO platforms. We discuss the I2PC architecture, development status, anticipated performance advantages, and limitations.

Increasing Linear Dynamic Range of a CMOS Image Sensor

NASA Technical Reports Server (NTRS)

Pain, Bedabrata

2007-01-01

A generic design and a corresponding operating sequence have been developed for increasing the linear-response dynamic range of a complementary metal oxide/semiconductor (CMOS) image sensor. The design provides for linear calibrated dual-gain pixels that operate at high gain at a low signal level and at low gain at a signal level above a preset threshold. Unlike most prior designs for increasing dynamic range of an image sensor, this design does not entail any increase in noise (including fixed-pattern noise), decrease in responsivity or linearity, or degradation of photometric calibration. The figure is a simplified schematic diagram showing the circuit of one pixel and pertinent parts of its column readout circuitry. The conventional part of the pixel circuit includes a photodiode having a small capacitance, CD. The unconventional part includes an additional larger capacitance, CL, that can be connected to the photodiode via a transfer gate controlled in part by a latch. In the high-gain mode, the signal labeled TSR in the figure is held low through the latch, which also helps to adapt the gain on a pixel-by-pixel basis. Light must be coupled to the pixel through a microlens or by back illumination in order to obtain a high effective fill factor; this is necessary to ensure high quantum efficiency, a loss of which would minimize the efficacy of the dynamic- range-enhancement scheme. Once the level of illumination of the pixel exceeds the threshold, TSR is turned on, causing the transfer gate to conduct, thereby adding CL to the pixel capacitance. The added capacitance reduces the conversion gain, and increases the pixel electron-handling capacity, thereby providing an extension of the dynamic range. By use of an array of comparators also at the bottom of the column, photocharge voltages on sampling capacitors in each column are compared with a reference voltage to determine whether it is necessary to switch from the high-gain to the low-gain mode. Depending upon the built-in offset in each pixel and in each comparator, the point at which the gain change occurs will be different, adding gain-dependent fixed pattern noise in each pixel. The offset, and hence the fixed pattern noise, is eliminated by sampling the pixel readout charge four times by use of four capacitors (instead of two such capacitors as in conventional design) connected to the bottom of the column via electronic switches SHS1, SHR1, SHS2, and SHR2, respectively, corresponding to high and low values of the signals TSR and RST. The samples are combined in an appropriate fashion to cancel offset-induced errors, and provide spurious-free imaging with extended dynamic range.

Photometric Calibration and Image Stitching for a Large Field of View Multi-Camera System

PubMed Central

Lu, Yu; Wang, Keyi; Fan, Gongshu

2016-01-01

A new compact large field of view (FOV) multi-camera system is introduced. The camera is based on seven tiny complementary metal-oxide-semiconductor sensor modules covering over 160° × 160° FOV. Although image stitching has been studied extensively, sensor and lens differences have not been considered in previous multi-camera devices. In this study, we have calibrated the photometric characteristics of the multi-camera device. Lenses were not mounted on the sensor in the process of radiometric response calibration to eliminate the influence of the focusing effect of uniform light from an integrating sphere. Linearity range of the radiometric response, non-linearity response characteristics, sensitivity, and dark current of the camera response function are presented. The R, G, and B channels have different responses for the same illuminance. Vignetting artifact patterns have been tested. The actual luminance of the object is retrieved by sensor calibration results, and is used to blend images to make panoramas reflect the objective luminance more objectively. This compensates for the limitation of stitching images that are more realistic only through the smoothing method. The dynamic range limitation of can be resolved by using multiple cameras that cover a large field of view instead of a single image sensor with a wide-angle lens. The dynamic range is expanded by 48-fold in this system. We can obtain seven images in one shot with this multi-camera system, at 13 frames per second. PMID:27077857

Imaging Subcellular Structures in the Living Zebrafish Embryo.

PubMed

Engerer, Peter; Plucinska, Gabriela; Thong, Rachel; Trovò, Laura; Paquet, Dominik; Godinho, Leanne

2016-04-02

In vivo imaging provides unprecedented access to the dynamic behavior of cellular and subcellular structures in their natural context. Performing such imaging experiments in higher vertebrates such as mammals generally requires surgical access to the system under study. The optical accessibility of embryonic and larval zebrafish allows such invasive procedures to be circumvented and permits imaging in the intact organism. Indeed the zebrafish is now a well-established model to visualize dynamic cellular behaviors using in vivo microscopy in a wide range of developmental contexts from proliferation to migration and differentiation. A more recent development is the increasing use of zebrafish to study subcellular events including mitochondrial trafficking and centrosome dynamics. The relative ease with which these subcellular structures can be genetically labeled by fluorescent proteins and the use of light microscopy techniques to image them is transforming the zebrafish into an in vivo model of cell biology. Here we describe methods to generate genetic constructs that fluorescently label organelles, highlighting mitochondria and centrosomes as specific examples. We use the bipartite Gal4-UAS system in multiple configurations to restrict expression to specific cell-types and provide protocols to generate transiently expressing and stable transgenic fish. Finally, we provide guidelines for choosing light microscopy methods that are most suitable for imaging subcellular dynamics.

Real-time motion artifacts compensation of ToF sensors data on GPU

NASA Astrophysics Data System (ADS)

Lefloch, Damien; Hoegg, Thomas; Kolb, Andreas

2013-05-01

Over the last decade, ToF sensors attracted many computer vision and graphics researchers. Nevertheless, ToF devices suffer from severe motion artifacts for dynamic scenes as well as low-resolution depth data which strongly justifies the importance of a valid correction. To counterbalance this effect, a pre-processing approach is introduced to greatly improve range image data on dynamic scenes. We first demonstrate the robustness of our approach using simulated data to finally validate our method using sensor range data. Our GPU-based processing pipeline enhances range data reliability in real-time.

Phase retrieval by coherent modulation imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Fucai; Chen, Bo; Morrison, Graeme R.

Phase retrieval is a long-standing problem in imaging when only the intensity of the wavefield can be recorded. Coherent diffraction imaging (CDI) is a lensless technique that uses iterative algorithms to recover amplitude and phase contrast images from diffraction intensity data. For general samples, phase retrieval from a single diffraction pattern has been an algorithmic and experimental challenge. Here we report a method of phase retrieval that uses a known modulation of the sample exit-wave. This coherent modulation imaging (CMI) method removes inherent ambiguities of CDI and uses a reliable, rapidly converging iterative algorithm involving three planes. It works formore » extended samples, does not require tight support for convergence, and relaxes dynamic range requirements on the detector. CMI provides a robust method for imaging in materials and biological science, while its single-shot capability will benefit the investigation of dynamical processes with pulsed sources, such as X-ray free electron laser.« less

Phase retrieval by coherent modulation imaging

DOE PAGES

Zhang, Fucai; Chen, Bo; Morrison, Graeme R.; ...

2016-11-18

Phase retrieval is a long-standing problem in imaging when only the intensity of the wavefield can be recorded. Coherent diffraction imaging (CDI) is a lensless technique that uses iterative algorithms to recover amplitude and phase contrast images from diffraction intensity data. For general samples, phase retrieval from a single diffraction pattern has been an algorithmic and experimental challenge. Here we report a method of phase retrieval that uses a known modulation of the sample exit-wave. This coherent modulation imaging (CMI) method removes inherent ambiguities of CDI and uses a reliable, rapidly converging iterative algorithm involving three planes. It works formore » extended samples, does not require tight support for convergence, and relaxes dynamic range requirements on the detector. CMI provides a robust method for imaging in materials and biological science, while its single-shot capability will benefit the investigation of dynamical processes with pulsed sources, such as X-ray free electron laser.« less

Novel dental dynamic depth profilometric imaging using simultaneous frequency-domain infrared photothermal radiometry and laser luminescence

NASA Astrophysics Data System (ADS)

Nicolaides, Lena; Mandelis, Andreas

2000-01-01

A high-spatial-resolution dynamic experimental imaging setup, which can provide simultaneous measurements of laser- induced frequency-domain infrared photothermal radiometric and luminescence signals from defects in teeth, has been developed for the first time. The major findings of this work are: (1) radiometric images are complementary to (anticorrelated with) luminescence images, as a result of the nature of the two physical signal generation processes; (2) the radiometric amplitude exhibits much superior dynamic (signal resolution) range to luminescence in distinguishing between intact and cracked sub-surface structures in the enamel; (3) the radiometric signal (amplitude and phase) produces dental images with much better defect localization, delineation, and resolution; (4) radiometric images (amplitude and phase) at a fixed modulation frequency are depth profilometric, whereas luminescence images are not; and (5) luminescence frequency responses from enamel and hydroxyapatite exhibit two relaxation lifetimes, the longer of which (approximately ms) is common to all and is not sensitive to the defect state and overall quality of the enamel. Simultaneous radiometric and luminescence frequency scans for the purpose of depth profiling were performed and a quantitative theoretical two-lifetime rate model of dental luminescence was advanced.

The Focusing Optics X-ray Solar Imager (FOXSI)

NASA Astrophysics Data System (ADS)

Krucker, S.

2011-12-01

The Focusing Optics X-ray Solar Imager (FOXSI) is a NASA Low Cost Access to Space sounding rocket payload that will launch in early 2012. A larger sensitivity and dynamic range than currently available are needed in order to image faint X-rays from electron beams in the tenuous corona, particularly those near the coronal acceleration region and those that escape into interplanetary space. FOXSI combines nested, grazing-incidence replicated optics with double-sided silicon strip detectors to achieve a dynamic range of >100 and a sensitivity 100 times that of RHESSI. Advances in the fabrication and assembly of the optics at the NASA Marshall Space Flight Center provide a spatial resolution of 8 arcseconds (FWHM), while the silicon detectors, developed by the Astro-H team at ISAS/JAXA, offer an energy resolution of 0.4 keV. FOXSI's first flight will conduct a search for nonthermal electrons in the quiet Sun, possibly related to nanoflares. FOXSI will serve as a pathfinder for future space-based solar hard X-ray spectroscopic imagers, which will be able to image nonthermal electrons in flare acceleration sites and provide quantitative measurements such as energy spectra, densities, and energy content in accelerated electrons.

The Focusing Optics X-ray Solar Imager

NASA Astrophysics Data System (ADS)

Glesener, Lindsay; Krucker, S.; Christe, S.; Ramsey, B.; Ishikawa, S.; Takahashi, T.; Saito, S.

2011-05-01

The Focusing Optics X-ray Solar Imager (FOXSI) is a NASA Low Cost Access to Space sounding rocket payload that will launch in late 2011. A larger sensitivity and dynamic range than currently available are needed in order to image faint X-rays from electron beams in the tenuous corona, particularly those near any coronal acceleration region and those that escape into interplanetary space. FOXSI combines fast-replication, nested, grazing-incidence optics with double-sided silicon strip detectors to achieve a dynamic range of >100 and a sensitivity 100 times that of RHESSI. Advances in the fabrication and assembly of the optics at the NASA Marshall Space Flight Center provide a spatial resolution of 8 arcseconds, while the silicon detectors, developed by the Astro-H team at ISAS/JAXA, offer an energy resolution of 0.5 keV. FOXSI's first flight will be used to conduct a search for X-ray emission from nonthermal electron beams in quiet Sun nanoflares. In addition, FOXSI will serve as a pathfinder for future space-based solar hard X-ray spectroscopic imagers, which will be able to image nonthermal electrons in flare acceleration sites and provide quantitative measurements such as energy spectra, densities, and energy content in accelerated electrons.

Quantitative evaluation of low-cost frame-grabber boards for personal computers.

PubMed

Kofler, J M; Gray, J E; Fuelberth, J T; Taubel, J P

1995-11-01

Nine moderately priced frame-grabber boards for both Macintosh (Apple Computers, Cupertino, CA) and IBM-compatible computers were evaluated using a Society of Motion Pictures and Television Engineers (SMPTE) pattern and a video signal generator for dynamic range, gray-scale reproducibility, and spatial integrity of the captured image. The degradation of the video information ranged from minor to severe. Some boards are of reasonable quality for applications in diagnostic imaging and education. However, price and quality are not necessarily directly related.

Global Swath and Gridded Data Tiling

NASA Technical Reports Server (NTRS)

Thompson, Charles K.

2012-01-01

This software generates cylindrically projected tiles of swath-based or gridded satellite data for the purpose of dynamically generating high-resolution global images covering various time periods, scaling ranges, and colors called "tiles." It reconstructs a global image given a set of tiles covering a particular time range, scaling values, and a color table. The program is configurable in terms of tile size, spatial resolution, format of input data, location of input data (local or distributed), number of processes run in parallel, and data conditioning.

ARC-2006-ACD06-0177-012

NASA Image and Video Library

2006-10-04

CEV (Crew Escape Vehicle) capsule Balistic Range testing to examine static and dynamic stability characteristics (at the Hypervelocity Free-Flight Facility) HFF - Chuck Cornelison viewing 8x10 shadowgraph images

HDR video synthesis for vision systems in dynamic scenes

NASA Astrophysics Data System (ADS)

Shopovska, Ivana; Jovanov, Ljubomir; Goossens, Bart; Philips, Wilfried

2016-09-01

High dynamic range (HDR) image generation from a number of differently exposed low dynamic range (LDR) images has been extensively explored in the past few decades, and as a result of these efforts a large number of HDR synthesis methods have been proposed. Since HDR images are synthesized by combining well-exposed regions of the input images, one of the main challenges is dealing with camera or object motion. In this paper we propose a method for the synthesis of HDR video from a single camera using multiple, differently exposed video frames, with circularly alternating exposure times. One of the potential applications of the system is in driver assistance systems and autonomous vehicles, involving significant camera and object movement, non- uniform and temporally varying illumination, and the requirement of real-time performance. To achieve these goals simultaneously, we propose a HDR synthesis approach based on weighted averaging of aligned radiance maps. The computational complexity of high-quality optical flow methods for motion compensation is still pro- hibitively high for real-time applications. Instead, we rely on more efficient global projective transformations to solve camera movement, while moving objects are detected by thresholding the differences between the trans- formed and brightness adapted images in the set. To attain temporal consistency of the camera motion in the consecutive HDR frames, the parameters of the perspective transformation are stabilized over time by means of computationally efficient temporal filtering. We evaluated our results on several reference HDR videos, on synthetic scenes, and using 14-bit raw images taken with a standard camera.

Astrophysical targets of the Fresnel diffractive imager

NASA Astrophysics Data System (ADS)

Koechlin, L.; Deba, P.; Raksasataya, T.

2017-11-01

The Fresnel Diffractive imager is an innovative concept of distributed space telescope, for high resolution (milli arc-seconds) spectro-imaging in the IR, visible and UV domains. This paper presents its optical principle and the science that can be done on potential astrophysical targets. The novelty lies in the primary optics: a binary Fresnel array, akin to a binary Fresnel zone plate. The main interest of this approach is the relaxed manufacturing and positioning constraints. While having the resolution and imaging capabilities of lens or mirrors of equivalent size, no optical material is involved in the focusing process: just vacuum. A Fresnel array consists of millions void subapertures punched into a large and thin opaque membrane, that focus light by diffraction into a compact and highly contrasted image. The positioning law of the aperture edges drives the image quality and contrast. This optical concept allows larger and lighter apertures than solid state optics, aiming to high angular resolution and high dynamic range imaging, in particular for UV applications. Diffraction focusing implies very long focal distances, up to dozens of kilometers, which requires at least a two-vessel formation flying in space. The first spacecraft, "the Fresnel Array spacecraft", holds the large punched foil: the Fresnel Array. The second, the "Receiver spacecraft" holds the field optics and focal instrumentation. A chromatism correction feature enables moderately large (20%) relative wavebands, and fields of a few to a dozen arc seconds. This Fresnel imager is adapted to high contrast stellar environments: dust disks, close companions and (we hope) exoplanets. Specific to the particular grid-like pattern of the primary focusing zone plate, is the very high dynamic range achieved in the images, in the case of compact objects. Large stellar photospheres may also be mapped with Fresnel arrays of a few meters opertaing in the UV. Larger and more complex fields can be imaged with a lesser dynamic range: galactic or extragalactic, or at the opposite distance scale: small solar system bodies. This paper will briefly address the optical principle, and in more detail the astrophysical missions and targets proposed for a 4-meter class demonstrator: - Exoplanet imaging, Exoplanet spectroscopic analysis in the visible and UV, - Stellar environments, young stellar systems, disks, - Galactic clouds, astrochemistry, - IR observation of the galactic center, - Small objects of our solar system.

High-Resolution Detector For X-Ray Diffraction

NASA Technical Reports Server (NTRS)

Carter, Daniel C.; Withrow, William K.; Pusey, Marc L.; Yost, Vaughn H.

1988-01-01

Proposed x-ray-sensitive imaging detector offers superior spatial resolution, counting-rate capacity, and dynamic range. Instrument based on laser-stimulated luminescence and reusable x-ray-sensitive film. Detector scans x-ray film line by line. Extracts latent image in film and simultaneously erases film for reuse. Used primarily for protein crystallography. Principle adapted to imaging detectors for electron microscopy and fluorescence spectroscopy and general use in astronomy, engineering, and medicine.

Chest CT window settings with multiscale adaptive histogram equalization: pilot study.

PubMed

Fayad, Laura M; Jin, Yinpeng; Laine, Andrew F; Berkmen, Yahya M; Pearson, Gregory D; Freedman, Benjamin; Van Heertum, Ronald

2002-06-01

Multiscale adaptive histogram equalization (MAHE), a wavelet-based algorithm, was investigated as a method of automatic simultaneous display of the full dynamic contrast range of a computed tomographic image. Interpretation times were significantly lower for MAHE-enhanced images compared with those for conventionally displayed images. Diagnostic accuracy, however, was insufficient in this pilot study to allow recommendation of MAHE as a replacement for conventional window display.

A potential non-invasive approach to evaluating blastocyst quality using biodynamic imaging

NASA Astrophysics Data System (ADS)

Li, Zhe; Ehmke, Natalie; Machaty, Zoltan; Nolte, David

2018-02-01

Biodynamic imaging (BDI) is capable of capturing the intracellular dynamics of blastocysts within a relatively short time. Spectroscopic signatures of embryos in the 0.01 Hz - 1 Hz range display responses to external factors before morphology changes take place. Viability evaluation is consistent with results from other non-invasive methods. Biodynamic imaging is a potential tool for selecting high quality embryos in clinical IVF practices.

High-dynamic range imaging techniques based on both color-separation algorithms used in conventional graphic arts and the human visual perception modeling

NASA Astrophysics Data System (ADS)

Lo, Mei-Chun; Hsieh, Tsung-Hsien; Perng, Ruey-Kuen; Chen, Jiong-Qiao

2010-01-01

The aim of this research is to derive illuminant-independent type of HDR imaging modules which can optimally multispectrally reconstruct of every color concerned in high-dynamic-range of original images for preferable cross-media color reproduction applications. Each module, based on either of broadband and multispectral approach, would be incorporated models of perceptual HDR tone-mapping, device characterization. In this study, an xvYCC format of HDR digital camera was used to capture HDR scene images for test. A tone-mapping module was derived based on a multiscale representation of the human visual system and used equations similar to a photoreceptor adaptation equation, proposed by Michaelis-Menten. Additionally, an adaptive bilateral type of gamut mapping algorithm, using approach of a multiple conversing-points (previously derived), was incorporated with or without adaptive Un-sharp Masking (USM) to carry out the optimization of HDR image rendering. An LCD with standard color space of Adobe RGB (D65) was used as a soft-proofing platform to display/represent HDR original RGB images, and also evaluate both renditionquality and prediction-performance of modules derived. Also, another LCD with standard color space of sRGB was used to test gamut-mapping algorithms, used to be integrated with tone-mapping module derived.

Scintillator high-gain avalanche rushing photoconductor active-matrix flat panel imager: Zero-spatial frequency x-ray imaging properties of the solid-state SHARP sensor structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wronski, M.; Zhao, W.; Tanioka, K.

Purpose: The authors are investigating the feasibility of a new type of solid-state x-ray imaging sensor with programmable avalanche gain: scintillator high-gain avalanche rushing photoconductor active matrix flat panel imager (SHARP-AMFPI). The purpose of the present work is to investigate the inherent x-ray detection properties of SHARP and demonstrate its wide dynamic range through programmable gain. Methods: A distributed resistive layer (DRL) was developed to maintain stable avalanche gain operation in a solid-state HARP. The signal and noise properties of the HARP-DRL for optical photon detection were investigated as a function of avalanche gain both theoretically and experimentally, and themore » results were compared with HARP tube (with electron beam readout) used in previous investigations of zero spatial frequency performance of SHARP. For this new investigation, a solid-state SHARP x-ray image sensor was formed by direct optical coupling of the HARP-DRL with a structured cesium iodide (CsI) scintillator. The x-ray sensitivity of this sensor was measured as a function of avalanche gain and the results were compared with the sensitivity of HARP-DRL measured optically. The dynamic range of HARP-DRL with variable avalanche gain was investigated for the entire exposure range encountered in radiography/fluoroscopy (R/F) applications. Results: The signal from HARP-DRL as a function of electric field showed stable avalanche gain, and the noise associated with the avalanche process agrees well with theory and previous measurements from a HARP tube. This result indicates that when coupled with CsI for x-ray detection, the additional noise associated with avalanche gain in HARP-DRL is negligible. The x-ray sensitivity measurements using the SHARP sensor produced identical avalanche gain dependence on electric field as the optical measurements with HARP-DRL. Adjusting the avalanche multiplication gain in HARP-DRL enabled a very wide dynamic range which encompassed all clinically relevant medical x-ray exposures. Conclusions: This work demonstrates that the HARP-DRL sensor enables the practical implementation of a SHARP solid-state x-ray sensor capable of quantum noise limited operation throughout the entire range of clinically relevant x-ray exposures. This is an important step toward the realization of a SHARP-AMFPI x-ray flat-panel imager.« less

ARC-2006-ACD06-0177-018

NASA Image and Video Library

2006-09-05

CEV (Crew Escape Vehicle) capsule Balistic Range testing to examine static and dynamic stability characteristics (at the Hypervelocity Free-Flight Facility) HFF - scans of shadowgraphs from 8x10 film images

ARC-2006-ACD06-0177-025

NASA Image and Video Library

2006-10-12

CEV (Crew Escape Vehicle) capsule Balistic Range testing to examine static and dynamic stability characteristics (at the Hypervelocity Free-Flight Facility) HFF - scans of shadowgraphs from 8x10 film images

ARC-2006-ACD06-0177-020

NASA Image and Video Library

2006-09-05

CEV (Crew Escape Vehicle) capsule Balistic Range testing to examine static and dynamic stability characteristics (at the Hypervelocity Free-Flight Facility) HFF - scans of shadowgraphs from 8x10 film images

ARC-2006-ACD06-0177-017

NASA Image and Video Library

2006-09-05

CEV (Crew Escape Vehicle) capsule Balistic Range testing to examine static and dynamic stability characteristics (at the Hypervelocity Free-Flight Facility) HFF - scans of shadowgraphs from 8x10 film images

ARC-2006-ACD06-0177-022

NASA Image and Video Library

2006-09-05

CEV (Crew Escape Vehicle) capsule Balistic Range testing to examine static and dynamic stability characteristics (at the Hypervelocity Free-Flight Facility) HFF - scans of shadowgraphs from 8x10 film images

4D multiple-cathode ultrafast electron microscopy

PubMed Central

Baskin, John Spencer; Liu, Haihua; Zewail, Ahmed H.

2014-01-01

Four-dimensional multiple-cathode ultrafast electron microscopy is developed to enable the capture of multiple images at ultrashort time intervals for a single microscopic dynamic process. The dynamic process is initiated in the specimen by one femtosecond light pulse and probed by multiple packets of electrons generated by one UV laser pulse impinging on multiple, spatially distinct, cathode surfaces. Each packet is distinctly recorded, with timing and detector location controlled by the cathode configuration. In the first demonstration, two packets of electrons on each image frame (of the CCD) probe different times, separated by 19 picoseconds, in the evolution of the diffraction of a gold film following femtosecond heating. Future elaborations of this concept to extend its capabilities and expand the range of applications of 4D ultrafast electron microscopy are discussed. The proof-of-principle demonstration reported here provides a path toward the imaging of irreversible ultrafast phenomena of materials, and opens the door to studies involving the single-frame capture of ultrafast dynamics using single-pump/multiple-probe, embedded stroboscopic imaging. PMID:25006261

4D multiple-cathode ultrafast electron microscopy.

PubMed

Baskin, John Spencer; Liu, Haihua; Zewail, Ahmed H

2014-07-22

Four-dimensional multiple-cathode ultrafast electron microscopy is developed to enable the capture of multiple images at ultrashort time intervals for a single microscopic dynamic process. The dynamic process is initiated in the specimen by one femtosecond light pulse and probed by multiple packets of electrons generated by one UV laser pulse impinging on multiple, spatially distinct, cathode surfaces. Each packet is distinctly recorded, with timing and detector location controlled by the cathode configuration. In the first demonstration, two packets of electrons on each image frame (of the CCD) probe different times, separated by 19 picoseconds, in the evolution of the diffraction of a gold film following femtosecond heating. Future elaborations of this concept to extend its capabilities and expand the range of applications of 4D ultrafast electron microscopy are discussed. The proof-of-principle demonstration reported here provides a path toward the imaging of irreversible ultrafast phenomena of materials, and opens the door to studies involving the single-frame capture of ultrafast dynamics using single-pump/multiple-probe, embedded stroboscopic imaging.

Biomedical terahertz imaging with a quantum cascade laser

NASA Astrophysics Data System (ADS)

Kim, Seongsin M.; Hatami, Fariba; Harris, James S.; Kurian, Allison W.; Ford, James; King, Douglas; Scalari, Giacomo; Giovannini, Marcella; Hoyler, Nicolas; Faist, Jerome; Harris, Geoff

2006-04-01

We present biomedical imaging using a single frequency terahertz imaging system based on a low threshold quantum cascade laser emitting at 3.7THz (λ=81μm). With a peak output power of 4mW, coherent terahertz radiation and detection provide a relatively large dynamic range and high spatial resolution. We study image contrast based on water/fat content ratios in different tissues. Terahertz transmission imaging demonstrates a distinct anatomy in a rat brain slice. We also demonstrate malignant tissue contrast in an image of a mouse liver with developed tumors, indicating potential use of terahertz imaging for probing cancerous tissues.

Imaging angiogenesis.

PubMed

Charnley, Natalie; Donaldson, Stephanie; Price, Pat

2009-01-01

There is a need for direct imaging of effects on tumor vasculature in assessment of response to antiangiogenic drugs and vascular disrupting agents. Imaging tumor vasculature depends on differences in permeability of vasculature of tumor and normal tissue, which cause changes in penetration of contrast agents. Angiogenesis imaging may be defined in terms of measurement of tumor perfusion and direct imaging of the molecules involved in angiogenesis. In addition, assessment of tumor hypoxia will give an indication of tumor vasculature. The range of imaging techniques available for these processes includes positron emission tomography (PET), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), perfusion computed tomography (CT), and ultrasound (US).

Tunable filters for multispectral imaging of aeronomical features

NASA Astrophysics Data System (ADS)

Goenka, C.; Semeter, J. L.; Noto, J.; Dahlgren, H.; Marshall, R.; Baumgardner, J.; Riccobono, J.; Migliozzi, M.

2013-10-01

Multispectral imaging of optical emissions in the Earth's upper atmosphere unravels vital information about dynamic phenomena in the Earth-space environment. Wavelength tunable filters allow us to accomplish this without using filter wheels or multiple imaging setups, but with identifiable caveats and trade-offs. We evaluate one such filter, a liquid crystal Fabry-Perot etalon, as a potential candidate for the next generation of imagers for aeronomy. The tunability of such a filter can be exploited in imaging features such as the 6300-6364 Å oxygen emission doublet, or studying the rotational temperature of N2+ in the 4200-4300 Å range, observations which typically require multiple instruments. We further discuss the use of this filter in an optical instrument, called the Liquid Crystal Hyperspectral Imager (LiCHI), which will be developed to make simultaneous measurements in various wavelength ranges.

Direct-conversion flat-panel imager with avalanche gain: Feasibility investigation for HARP-AMFPI

PubMed Central

Wronski, M. M.; Rowlands, J. A.

2008-01-01

The authors are investigating the concept of a direct-conversion flat-panel imager with avalanche gain for low-dose x-ray imaging. It consists of an amorphous selenium (a-Se) photoconductor partitioned into a thick drift region for x-ray-to-charge conversion and a relatively thin region called high-gain avalanche rushing photoconductor (HARP) in which the charge undergoes avalanche multiplication. An active matrix of thin film transistors is used to read out the electronic image. The authors call the proposed imager HARP active matrix flat panel imager (HARP-AMFPI). The key advantages of HARP-AMFPI are its high spatial resolution, owing to the direct-conversion a-Se layer, and its programmable avalanche gain, which can be enabled during low dose fluoroscopy to overcome electronic noise and disabled during high dose radiography to prevent saturation of the detector elements. This article investigates key design considerations for HARP-AMFPI. The effects of electronic noise on the imaging performance of HARP-AMFPI were modeled theoretically and system parameters were optimized for radiography and fluoroscopy. The following imager properties were determined as a function of avalanche gain: (1) the spatial frequency dependent detective quantum efficiency; (2) fill factor; (3) dynamic range and linearity; and (4) gain nonuniformities resulting from electric field strength nonuniformities. The authors results showed that avalanche gains of 5 and 20 enable x-ray quantum noise limited performance throughout the entire exposure range in radiography and fluoroscopy, respectively. It was shown that HARP-AMFPI can provide the required gain while maintaining a 100% effective fill factor and a piecewise dynamic range over five orders of magnitude (10−7–10−2 R∕frame). The authors have also shown that imaging performance is not significantly affected by the following: electric field strength nonuniformities, avalanche noise for x-ray energies above 1 keV and direct interaction of x rays in the gain region. Thus, HARP-AMFPI is a promising flat-panel imager structure that enables high-resolution fully quantum noise limited x-ray imaging over a wide exposure range. PMID:19175080

Direct-conversion flat-panel imager with avalanche gain: Feasibility investigation for HARP-AMFPI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wronski, M. M.; Rowlands, J. A.

2008-12-15

The authors are investigating the concept of a direct-conversion flat-panel imager with avalanche gain for low-dose x-ray imaging. It consists of an amorphous selenium (a-Se) photoconductor partitioned into a thick drift region for x-ray-to-charge conversion and a relatively thin region called high-gain avalanche rushing photoconductor (HARP) in which the charge undergoes avalanche multiplication. An active matrix of thin film transistors is used to read out the electronic image. The authors call the proposed imager HARP active matrix flat panel imager (HARP-AMFPI). The key advantages of HARP-AMFPI are its high spatial resolution, owing to the direct-conversion a-Se layer, and its programmablemore » avalanche gain, which can be enabled during low dose fluoroscopy to overcome electronic noise and disabled during high dose radiography to prevent saturation of the detector elements. This article investigates key design considerations for HARP-AMFPI. The effects of electronic noise on the imaging performance of HARP-AMFPI were modeled theoretically and system parameters were optimized for radiography and fluoroscopy. The following imager properties were determined as a function of avalanche gain: (1) the spatial frequency dependent detective quantum efficiency; (2) fill factor; (3) dynamic range and linearity; and (4) gain nonuniformities resulting from electric field strength nonuniformities. The authors results showed that avalanche gains of 5 and 20 enable x-ray quantum noise limited performance throughout the entire exposure range in radiography and fluoroscopy, respectively. It was shown that HARP-AMFPI can provide the required gain while maintaining a 100% effective fill factor and a piecewise dynamic range over five orders of magnitude (10{sup -7}-10{sup -2} R/frame). The authors have also shown that imaging performance is not significantly affected by the following: electric field strength nonuniformities, avalanche noise for x-ray energies above 1 keV and direct interaction of x rays in the gain region. Thus, HARP-AMFPI is a promising flat-panel imager structure that enables high-resolution fully quantum noise limited x-ray imaging over a wide exposure range.« less

HDR imaging and color constancy: two sides of the same coin?

NASA Astrophysics Data System (ADS)

McCann, John J.

2011-01-01

At first, we think that High Dynamic Range (HDR) imaging is a technique for improved recordings of scene radiances. Many of us think that human color constancy is a variation of a camera's automatic white balance algorithm. However, on closer inspection, glare limits the range of light we can detect in cameras and on retinas. All scene regions below middle gray are influenced, more or less, by the glare from the bright scene segments. Instead of accurate radiance reproduction, HDR imaging works well because it preserves the details in the scene's spatial contrast. Similarly, on closer inspection, human color constancy depends on spatial comparisons that synthesize appearances from all the scene segments. Can spatial image processing play similar principle roles in both HDR imaging and color constancy?

Research on HDR image fusion algorithm based on Laplace pyramid weight transform with extreme low-light CMOS

NASA Astrophysics Data System (ADS)

Guan, Wen; Li, Li; Jin, Weiqi; Qiu, Su; Zou, Yan

2015-10-01

Extreme-Low-Light CMOS has been widely applied in the field of night-vision as a new type of solid image sensor. But if the illumination in the scene has drastic changes or the illumination is too strong, Extreme-Low-Light CMOS can't both clearly present the high-light scene and low-light region. According to the partial saturation problem in the field of night-vision, a HDR image fusion algorithm based on the Laplace Pyramid was researched. The overall gray value and the contrast of the low light image is very low. We choose the fusion strategy based on regional average gradient for the top layer of the long exposure image and short exposure image, which has rich brightness and textural features. The remained layers which represent the edge feature information of the target are based on the fusion strategy based on regional energy. In the process of source image reconstruction with Laplacian pyramid image, we compare the fusion results with four kinds of basal images. The algorithm is tested using Matlab and compared with the different fusion strategies. We use information entropy, average gradient and standard deviation these three objective evaluation parameters for the further analysis of the fusion result. Different low illumination environment experiments show that the algorithm in this paper can rapidly get wide dynamic range while keeping high entropy. Through the verification of this algorithm features, there is a further application prospect of the optimized algorithm. Keywords: high dynamic range imaging, image fusion, multi-exposure image, weight coefficient, information fusion, Laplacian pyramid transform.

Aerosol scattering and absorption modulation transfer function

NASA Astrophysics Data System (ADS)

Sadot, Dan; Kopeika, Norman S.

1993-08-01

Recent experimental measurements of overall atmospheric modulation transfer function (MTF) indicate significant difference between the turbulence and overall atmospheric MTFs, except often at midday when turbulence is strong. We suggest here a physical explanation for those results which essentially relates to what we call a practical instrumentation-based atmospheric aerosol MTF which is a modification of the classical aerosol MTF theory. It is shown that system field-of-view and dynamic range affect strongly aerosol and overall atmospheric MTFs. It is often necessary to choose between MTF and SNR depending upon dynamic range requirements. Also, a new approach regarding aerosol absorption is presented. It is shown that aerosol-absorbed irradiance is spatial frequency dependent and enhances the degradation in image quality arising from received scattered light. This is most relevant for thermal imaging. An analytically corrected model for the aerosol MTF is presented which is relevant for imaging. An important conclusion is that the aerosol MTF is often the dominant part in the actual overall atmospheric MTF all across the optical spectral region.

Formulation of image quality prediction criteria for the Viking lander camera

NASA Technical Reports Server (NTRS)

Huck, F. O.; Jobson, D. J.; Taylor, E. J.; Wall, S. D.

1973-01-01

Image quality criteria are defined and mathematically formulated for the prediction computer program which is to be developed for the Viking lander imaging experiment. The general objective of broad-band (black and white) imagery to resolve small spatial details and slopes is formulated as the detectability of a right-circular cone with surface properties of the surrounding terrain. The general objective of narrow-band (color and near-infrared) imagery to observe spectral characteristics if formulated as the minimum detectable albedo variation. The general goal to encompass, but not exceed, the range of the scene radiance distribution within single, commandable, camera dynamic range setting is also considered.

Subcellular metabolic contrast in living tissue using dynamic full field OCT (D-FFOCT) (Conference Presentation)

NASA Astrophysics Data System (ADS)

Apelian, Clement; Harms, Fabrice; Thouvenin, Olivier; Boccara, Claude A.

2016-03-01

Cells shape or density is an important marker of tissues pathology. However, individual cells are difficult to observe in thick tissues frequently presenting highly scattering structures such as collagen fibers. Endogenous techniques struggle to image cells in these conditions. Moreover, exogenous contrast agents like dyes, fluorophores or nanoparticles cannot always be used, especially if non-invasive imaging is required. Scatterers motion happening down to the millisecond scale, much faster than the fix and highly scattering structures (global motion of the tissue), allowed us to develop a new approach based on the time dependence of the FF-OCT signals. This method reveals hidden cells after a spatiotemporal analysis based on singular value decomposition and wavelet analysis concepts. It does also give us access to local dynamics of imaged scatterers. This dynamic information is linked with the local metabolic activity that drives these scatterers. Our technique can explore subcellular scales with micrometric resolution and dynamics ranging from the millisecond to seconds. By this mean we studied a wide range of tissues, animal and human in both normal and pathological conditions (cancer, ischemia, osmotic shock…) in different organs such as liver, kidney, and brain among others. Different cells, undetectable with FF-OCT, were identified (erythrocytes, hepatocytes…). Different scatterer clusters express different characteristic times and thus can be related to different mechanisms that we identify with metabolic functions. We are confident that the D-FFOCT, by accessing to a new spatiotemporal metabolic contrast, will be a leading technique on tissue imaging and could lead to better medical diagnosis.

Display of high dynamic range images under varying viewing conditions

NASA Astrophysics Data System (ADS)

Borer, Tim

2017-09-01

Recent demonstrations of high dynamic range (HDR) television have shown that superb images are possible. With the emergence of an HDR television production standard (ITU-R Recommendation BT.2100) last year, HDR television production is poised to take off. However research to date has focused principally on HDR image display only under "dark" viewing conditions. HDR television will need to be displayed at varying brightness and under varying illumination (for example to view sport in daytime or on mobile devices). We know, from common practice with conventional TV, that the rendering intent (gamma) should change under brighter conditions, although this is poorly quantified. For HDR the need to render images under varying conditions is all the more acute. This paper seeks to explore the issues surrounding image display under varying conditions. It also describes how visual adaptation is affected by display brightness, surround illumination, screen size and viewing distance. Existing experimental results are presented and extended to try to quantify these effects. Using the experimental results it is described how HDR images may be displayed so that they are perceptually equivalent under different viewing conditions. A new interpretation of the experimental results is reported, yielding a new, luminance invariant model for the appropriate display "gamma". In this way the consistency of HDR image reproduction should be improved, thereby better maintaining "creative intent" in television.

Preference limits of the visual dynamic range for ultra high quality and aesthetic conveyance

NASA Astrophysics Data System (ADS)

Daly, Scott; Kunkel, Timo; Sun, Xing; Farrell, Suzanne; Crum, Poppy

2013-03-01

A subjective study was conducted to investigate the preferred maximum and minimum display luminances in order to determine the dynamic ranges for future displays. Two studies address the diffuse reflective regions, and a third study tested preferences of highlight regions. Preferences, as opposed to detection thresholds, were studied to provide results more directly relevant to the viewing of entertainment or art. Test images were specifically designed to test these limits without the perceptual conflicts that usually occur in these types of studies. For the diffuse range, we found a display with a dynamic range having luminances between 0.1 and 650 cd/m2 matches the average preferences. However, to satisfy 90% of the population, a dynamic range from 0.005 and ~3,000 cd/m2 is needed. Since a display should be able to produce values brighter than the diffuse white maximum, as in specular highlights and emissive sources, the highlight study concludes that even the average preferred maximum luminance for highlight reproduction is ~4,000 cd/m2.

Coronal Magnetic Field Measurement from EUV Images Made by the Solar Dynamics Observatory

NASA Technical Reports Server (NTRS)

Gopalswamy, Natchimuthuk; Nitta, Nariaki; Akiyama, Sachiko; Makela, Pertti; Yashiro, Seiji

2012-01-01

By measuring the geometrical properties of the coronal mass ejection (CME) flux rope and the leading shock observed on 2010 June 13 by the Solar Dynamics Observatory (SDO) mission's Atmospheric Imaging Assembly we determine the Alfven speed and the magnetic field strength in the inner corona at a heliocentric distance of approx. 1.4 Rs The basic measurements are the shock standoff distance (Delta R) ahead of the CME flux rope, the radius of curvature of the flux rope (R(sub c)), and the shock speed. We first derive the Alfvenic Mach number (M) using the relationship, Delta R/R(sub c) = 0.81[(gamma-1) M(exp 2) + 2] / [(gamma +1)(M2 - 1)], where gamma is the only parameter that needed to be assumed. For gamma = 4/3, the Mach number declined from 3.7 to 1.5 indicating shock weakening within the field of view of the imager. The shock formation coincided with the appearance of a type II radio burst at a frequency of approx. 300 MHz (harmonic component), providing an independent confirmation of the shock. The shock compression ratio derived from the radio dynamic spectrum was found to be consistent with that derived from the theory of fast-mode MHD shocks. From the measured shock speed and the derived Mach number, we found the Alfven speed to increase from approx 140 km/s to 460 km/s over the distance range 1.2-1.5 Rs. By deriving the upstream plasma density from the emission frequency of the associated type II radio burst, we determined the coronal magnetic field to be in the range 1.3-1.5 G. The derived magnetic field values are consistent with other estimates in a similar distance range. This work demonstrates that the EUV imagers, in the presence of radio dynamic spectra, can be used as coronal magnetometers

Digital optical tomography system for dynamic breast imaging

NASA Astrophysics Data System (ADS)

Flexman, Molly L.; Khalil, Michael A.; Al Abdi, Rabah; Kim, Hyun K.; Fong, Christopher J.; Desperito, Elise; Hershman, Dawn L.; Barbour, Randall L.; Hielscher, Andreas H.

2011-07-01

Diffuse optical tomography has shown promising results as a tool for breast cancer screening and monitoring response to chemotherapy. Dynamic imaging of the transient response of the breast to an external stimulus, such as pressure or a respiratory maneuver, can provide additional information that can be used to detect tumors. We present a new digital continuous-wave optical tomography system designed to simultaneously image both breasts at fast frame rates and with a large number of sources and detectors. The system uses a master-slave digital signal processor-based detection architecture to achieve a dynamic range of 160 dB and a frame rate of 1.7 Hz with 32 sources, 64 detectors, and 4 wavelengths per breast. Included is a preliminary study of one healthy patient and two breast cancer patients showing the ability to identify an invasive carcinoma based on the hemodynamic response to a breath hold.

Local contrast-enhanced MR images via high dynamic range processing.

PubMed

Chandra, Shekhar S; Engstrom, Craig; Fripp, Jurgen; Neubert, Ales; Jin, Jin; Walker, Duncan; Salvado, Olivier; Ho, Charles; Crozier, Stuart

2018-09-01

To develop a local contrast-enhancing and feature-preserving high dynamic range (HDR) image processing algorithm for multichannel and multisequence MR images of multiple body regions and tissues, and to evaluate its performance for structure visualization, bias field (correction) mitigation, and automated tissue segmentation. A multiscale-shape and detail-enhancement HDR-MRI algorithm is applied to data sets of multichannel and multisequence MR images of the brain, knee, breast, and hip. In multisequence 3T hip images, agreement between automatic cartilage segmentations and corresponding synthesized HDR-MRI series were computed for mean voxel overlap established from manual segmentations for a series of cases. Qualitative comparisons between the developed HDR-MRI and standard synthesis methods were performed on multichannel 7T brain and knee data, and multisequence 3T breast and knee data. The synthesized HDR-MRI series provided excellent enhancement of fine-scale structure from multiple scales and contrasts, while substantially reducing bias field effects in 7T brain gradient echo, T 1 and T 2 breast images and 7T knee multichannel images. Evaluation of the HDR-MRI approach on 3T hip multisequence images showed superior outcomes for automatic cartilage segmentations with respect to manual segmentation, particularly around regions with hyperintense synovial fluid, across a set of 3D sequences. The successful combination of multichannel/sequence MR images into a single-fused HDR-MR image format provided consolidated visualization of tissues within 1 omnibus image, enhanced definition of thin, complex anatomical structures in the presence of variable or hyperintense signals, and improved tissue (cartilage) segmentation outcomes. © 2018 International Society for Magnetic Resonance in Medicine.

Cardiac motion correction based on partial angle reconstructed images in x-ray CT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Seungeon; Chang, Yongjin; Ra, Jong Beom, E-mail: jbra@kaist.ac.kr

2015-05-15

Purpose: Cardiac x-ray CT imaging is still challenging due to heart motion, which cannot be ignored even with the current rotation speed of the equipment. In response, many algorithms have been developed to compensate remaining motion artifacts by estimating the motion using projection data or reconstructed images. In these algorithms, accurate motion estimation is critical to the compensated image quality. In addition, since the scan range is directly related to the radiation dose, it is preferable to minimize the scan range in motion estimation. In this paper, the authors propose a novel motion estimation and compensation algorithm using a sinogrammore » with a rotation angle of less than 360°. The algorithm estimates the motion of the whole heart area using two opposite 3D partial angle reconstructed (PAR) images and compensates the motion in the reconstruction process. Methods: A CT system scans the thoracic area including the heart over an angular range of 180° + α + β, where α and β denote the detector fan angle and an additional partial angle, respectively. The obtained cone-beam projection data are converted into cone-parallel geometry via row-wise fan-to-parallel rebinning. Two conjugate 3D PAR images, whose center projection angles are separated by 180°, are then reconstructed with an angular range of β, which is considerably smaller than a short scan range of 180° + α. Although these images include limited view angle artifacts that disturb accurate motion estimation, they have considerably better temporal resolution than a short scan image. Hence, after preprocessing these artifacts, the authors estimate a motion model during a half rotation for a whole field of view via nonrigid registration between the images. Finally, motion-compensated image reconstruction is performed at a target phase by incorporating the estimated motion model. The target phase is selected as that corresponding to a view angle that is orthogonal to the center view angles of two conjugate PAR images. To evaluate the proposed algorithm, digital XCAT and physical dynamic cardiac phantom datasets are used. The XCAT phantom datasets were generated with heart rates of 70 and 100 bpm, respectively, by assuming a system rotation time of 300 ms. A physical dynamic cardiac phantom was scanned using a slowly rotating XCT system so that the effective heart rate will be 70 bpm for a system rotation speed of 300 ms. Results: In the XCAT phantom experiment, motion-compensated 3D images obtained from the proposed algorithm show coronary arteries with fewer motion artifacts for all phases. Moreover, object boundaries contaminated by motion are well restored. Even though object positions and boundary shapes are still somewhat different from the ground truth in some cases, the authors see that visibilities of coronary arteries are improved noticeably and motion artifacts are reduced considerably. The physical phantom study also shows that the visual quality of motion-compensated images is greatly improved. Conclusions: The authors propose a novel PAR image-based cardiac motion estimation and compensation algorithm. The algorithm requires an angular scan range of less than 360°. The excellent performance of the proposed algorithm is illustrated by using digital XCAT and physical dynamic cardiac phantom datasets.« less

Denoising time-resolved microscopy image sequences with singular value thresholding.

PubMed

Furnival, Tom; Leary, Rowan K; Midgley, Paul A

2017-07-01

Time-resolved imaging in microscopy is important for the direct observation of a range of dynamic processes in both the physical and life sciences. However, the image sequences are often corrupted by noise, either as a result of high frame rates or a need to limit the radiation dose received by the sample. Here we exploit both spatial and temporal correlations using low-rank matrix recovery methods to denoise microscopy image sequences. We also make use of an unbiased risk estimator to address the issue of how much thresholding to apply in a robust and automated manner. The performance of the technique is demonstrated using simulated image sequences, as well as experimental scanning transmission electron microscopy data, where surface adatom motion and nanoparticle structural dynamics are recovered at rates of up to 32 frames per second. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Techniques in helical scanning, dynamic imaging and image segmentation for improved quantitative analysis with X-ray micro-CT

NASA Astrophysics Data System (ADS)

Sheppard, Adrian; Latham, Shane; Middleton, Jill; Kingston, Andrew; Myers, Glenn; Varslot, Trond; Fogden, Andrew; Sawkins, Tim; Cruikshank, Ron; Saadatfar, Mohammad; Francois, Nicolas; Arns, Christoph; Senden, Tim

2014-04-01

This paper reports on recent advances at the micro-computed tomography facility at the Australian National University. Since 2000 this facility has been a significant centre for developments in imaging hardware and associated software for image reconstruction, image analysis and image-based modelling. In 2010 a new instrument was constructed that utilises theoretically-exact image reconstruction based on helical scanning trajectories, allowing higher cone angles and thus better utilisation of the available X-ray flux. We discuss the technical hurdles that needed to be overcome to allow imaging with cone angles in excess of 60°. We also present dynamic tomography algorithms that enable the changes between one moment and the next to be reconstructed from a sparse set of projections, allowing higher speed imaging of time-varying samples. Researchers at the facility have also created a sizeable distributed-memory image analysis toolkit with capabilities ranging from tomographic image reconstruction to 3D shape characterisation. We show results from image registration and present some of the new imaging and experimental techniques that it enables. Finally, we discuss the crucial question of image segmentation and evaluate some recently proposed techniques for automated segmentation.

Clinical evaluation of a medical high dynamic range display

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marchessoux, Cedric, E-mail: cedric.marchessoux@ba

Purpose: Recent new medical displays do have higher contrast and higher luminance but do not have a High Dynamic Range (HDR). HDR implies a minimum luminance value close to zero. A medical HDR display prototype based on two Liquid Crystal layers has been developed. The goal of this study is to evaluate the potential clinical benefit of such display in comparison with a low dynamic range (LDR) display. Methods: The study evaluated the clinical performance of the displays in a search and detection task. Eight radiologists read chest x-ray images some of which contained simulated lung nodules. The study usedmore » a JAFROC (Jacknife Free Receiver Operating Characteristic) approach for analyzing FROC data. The calculated figure of merit (FoM) is the probability that a lesion is rated higher than all rated nonlesions on all images. Time per case and accuracy for locating the center of the nodules were also compared. The nodules were simulated using Samei’s model. 214 CR and DR images [half were “healthy images” (chest nodule-free) and half “diseased images”] were used resulting in a total number of nodules equal to 199 with 25 images with 1 nodule, 51 images with 2 nodules, and 24 images with 3 nodules. A dedicated software interface was designed for visualizing the images for each session. For the JAFROC1 statistical analysis, the study is done per nodule category: all nodules, difficult nodules, and very difficult nodules. Results: For all nodules, the averaged FoM{sub HDR} is slightly higher than FoM{sub LDR} with 0.09% of difference. For the difficult nodules, the averaged FoM{sub HDR} is slightly higher than FoM{sub LDR} with 1.38% of difference. The averaged FoM{sub HDR} is slightly higher than FoM{sub LDR} with 0.71% of difference. For the true positive fraction (TPF), both displays (the HDR and the LDR ones) have similar TPF for all nodules, but looking at difficult and very difficult nodules, there are more TP for the HDR display. The true positive fraction has been also computed in function of the local average luminance around the nodules. For the lowest luminance range, there is more than 30% in favor of the HDR display. For the highest luminance range, there is less than 6% in favor of the LDR display. Conclusions: This study shows the potential benefit of using a HDR display in radiology.« less

Optimizing Radiometric Fidelity to Enhance Aerial Image Change Detection Utilizing Digital Single Lens Reflex (DSLR) Cameras

NASA Astrophysics Data System (ADS)

Kerr, Andrew D.

Determining optimal imaging settings and best practices related to the capture of aerial imagery using consumer-grade digital single lens reflex (DSLR) cameras, should enable remote sensing scientists to generate consistent, high quality, and low cost image data sets. Radiometric optimization, image fidelity, image capture consistency and repeatability were evaluated in the context of detailed image-based change detection. The impetus for this research is in part, a dearth of relevant, contemporary literature, on the utilization of consumer grade DSLR cameras for remote sensing, and the best practices associated with their use. The main radiometric control settings on a DSLR camera, EV (Exposure Value), WB (White Balance), light metering, ISO, and aperture (f-stop), are variables that were altered and controlled over the course of several image capture missions. These variables were compared for their effects on dynamic range, intra-frame brightness variation, visual acuity, temporal consistency, and the detectability of simulated cracks placed in the images. This testing was conducted from a terrestrial, rather than an airborne collection platform, due to the large number of images per collection, and the desire to minimize inter-image misregistration. The results point to a range of slightly underexposed image exposure values as preferable for change detection and noise minimization fidelity. The makeup of the scene, the sensor, and aerial platform, influence the selection of the aperture and shutter speed which along with other variables, allow for estimation of the apparent image motion (AIM) motion blur in the resulting images. The importance of the image edges in the image application, will in part dictate the lowest usable f-stop, and allow the user to select a more optimal shutter speed and ISO. The single most important camera capture variable is exposure bias (EV), with a full dynamic range, wide distribution of DN values, and high visual contrast and acuity occurring around -0.7 to -0.3EV exposure bias. The ideal values for sensor gain, was found to be ISO 100, with ISO 200 a less desirable. This study offers researchers a better understanding of the effects of camera capture settings on RSI pairs and their influence on image-based change detection.

Hyperspectral CMOS imager

NASA Astrophysics Data System (ADS)

Jerram, P. A.; Fryer, M.; Pratlong, J.; Pike, A.; Walker, A.; Dierickx, B.; Dupont, B.; Defernez, A.

2017-11-01

CCDs have been used for many years for Hyperspectral imaging missions and have been extremely successful. These include the Medium Resolution Imaging Spectrometer (MERIS) [1] on Envisat, the Compact High Resolution Imaging Spectrometer (CHRIS) on Proba and the Ozone Monitoring Instrument operating in the UV spectral region. ESA are also planning a number of further missions that are likely to use CCD technology (Sentinel 3, 4 and 5). However CMOS sensors have a number of advantages which means that they will probably be used for hyperspectral applications in the longer term. There are two main advantages with CMOS sensors: First a hyperspectral image consists of spectral lines with a large difference in intensity; in a frame transfer CCD the faint spectral lines have to be transferred through the part of the imager illuminated by intense lines. This can lead to cross-talk and whilst this problem can be reduced by the use of split frame transfer and faster line rates CMOS sensors do not require a frame transfer and hence inherently will not suffer from this problem. Second, with a CMOS sensor the intense spectral lines can be read multiple times within a frame to give a significant increase in dynamic range. We will describe the design, and initial test of a CMOS sensor for use in hyperspectral applications. This device has been designed to give as high a dynamic range as possible with minimum cross-talk. The sensor has been manufactured on high resistivity epitaxial silicon wafers and is be back-thinned and left relatively thick in order to obtain the maximum quantum efficiency across the entire spectral range

Optical Demonstration of a Medical Imaging System with an EMCCD-Sensor Array for Use in a High Resolution Dynamic X-ray Imager

PubMed Central

Qu, Bin; Huang, Ying; Wang, Weiyuan; Sharma, Prateek; Kuhls-Gilcrist, Andrew T.; Cartwright, Alexander N.; Titus, Albert H.; Bednarek, Daniel R.; Rudin, Stephen

2011-01-01

Use of an extensible array of Electron Multiplying CCDs (EMCCDs) in medical x-ray imager applications was demonstrated for the first time. The large variable electronic-gain (up to 2000) and small pixel size of EMCCDs provide effective suppression of readout noise compared to signal, as well as high resolution, enabling the development of an x-ray detector with far superior performance compared to conventional x-ray image intensifiers and flat panel detectors. We are developing arrays of EMCCDs to overcome their limited field of view (FOV). In this work we report on an array of two EMCCD sensors running simultaneously at a high frame rate and optically focused on a mammogram film showing calcified ducts. The work was conducted on an optical table with a pulsed LED bar used to provide a uniform diffuse light onto the film to simulate x-ray projection images. The system can be selected to run at up to 17.5 frames per second or even higher frame rate with binning. Integration time for the sensors can be adjusted from 1 ms to 1000 ms. Twelve-bit correlated double sampling AD converters were used to digitize the images, which were acquired by a National Instruments dual-channel Camera Link PC board in real time. A user-friendly interface was programmed using LabVIEW to save and display 2K × 1K pixel matrix digital images. The demonstration tiles a 2 × 1 array to acquire increased-FOV stationary images taken at different gains and fluoroscopic-like videos recorded by scanning the mammogram simultaneously with both sensors. The results show high resolution and high dynamic range images stitched together with minimal adjustments needed. The EMCCD array design allows for expansion to an M×N array for arbitrarily larger FOV, yet with high resolution and large dynamic range maintained. PMID:23505330

Cassini/MIMI Measurements in Saturn's Magnetosphere and their Implications for Magnetospheric Dynamics

NASA Astrophysics Data System (ADS)

Mitchell, D. G.

2016-12-01

The Cassini spacecraft has been in orbit about Saturn since early July, 2004. In less than a year, on September 15, 2017, Cassini will plunge into Saturn's atmosphere, ending what has been a highly successful and interesting mission. As befitting a Planetary Division Flagship Mission, Cassini's science payload included instrumentation designed for a multitude of science objectives, from surfaces of moons to rings to atmospheres to Saturn's vast, fast-rotating magnetosphere. Saturn's magnetosphere exhibits considerable variability, both from inner magnetosphere to outer, and over time. Characterizing the dynamics of the magnetosphere has required the full range of energetic particles (measured by the magnetospheric imaging instrument, MIMI - https://saturn.jpl.nasa.gov/magnetospheric-imaging-instrument/), plasma (provided by the Cassini plasma spectrometer, CAPS), gas (ion and neutral mass spectrometer, INMS), magnetic fields (Cassini magnetometer, MAG), radio and plasma waves (radio and plasma wave science, RPWS), dust (Cassini Dust Analyzer, CDA), as well as ultraviolet, visible and infrared imaging (ultraviolet imaging spectrograph, UVIS; Cassini imaging subsystem ISS; visible and infrared mapping spectrometer, VIMS; Cassini composite infrared spectrometer, CIRS) and ionospheric sounding by the Cassini radio science subsystem (RSS). It has also required the full range of orbital geometries from equatorial to high inclination and all local times, as well as the full range of solar wind conditions, seasonal sun-Saturn configurations. In this talk we focus on the contributions of the MIMI instrument suite (CHEMS, LEMMS, and INCA) to our understanding of the dynamics of Saturn's magnetosphere. We will both review past work, and present recent observations from the high inclination orbits that precede the final stages of the Cassini mission, the sets of high inclination orbits that cross the equator just beyond the edge of the main ring system, and later cross between the inner edge of the main rings and Saturn's upper atmosphere. We highlight processes including radiation belt generation, particle precipitation into Titan's atmosphere, icy moon interactions, magnetotail reconnection, flux tube interchange, solar wind-driven dynamics, and connection to auroral displays.

Satellite image collection optimization

NASA Astrophysics Data System (ADS)

Martin, William

2002-09-01

Imaging satellite systems represent a high capital cost. Optimizing the collection of images is critical for both satisfying customer orders and building a sustainable satellite operations business. We describe the functions of an operational, multivariable, time dynamic optimization system that maximizes the daily collection of satellite images. A graphical user interface allows the operator to quickly see the results of what if adjustments to an image collection plan. Used for both long range planning and daily collection scheduling of Space Imaging's IKONOS satellite, the satellite control and tasking (SCT) software allows collection commands to be altered up to 10 min before upload to the satellite.

Software-based stacking techniques to enhance depth of field and dynamic range in digital photomicrography.

PubMed

Piper, Jörg

2010-01-01

Several software solutions are powerful tools to enhance the depth of field and improve focus in digital photomicrography. By these means, the focal depth can be fundamentally optimized so that three-dimensional structures within specimens can be documented with superior quality. Thus, images can be created in light microscopy which will be comparable with scanning electron micrographs. The remaining sharpness will no longer be dependent on the specimen's vertical dimension or its range in regional thickness. Moreover, any potential lack of definition associated with loss of planarity and unsteadiness in the visual accommodation can be mitigated or eliminated so that the contour sharpness and resolution can be strongly enhanced.Through the use of complementary software, ultrahigh ranges in brightness and contrast (the so-called high-dynamic range) can be corrected so that the final images will also be free from locally over- or underexposed zones. Furthermore, fine detail in low natural contrast can be visualized in much higher clarity. Fundamental enhancements of the global visual information will result from both techniques.

Influence of range-gated intensifiers on underwater imaging system SNR

NASA Astrophysics Data System (ADS)

Wang, Xia; Hu, Ling; Zhi, Qiang; Chen, Zhen-yue; Jin, Wei-qi

2013-08-01

Range-gated technology has been a hot research field in recent years due to its high effective back scattering eliminating. As a result, it can enhance the contrast between a target and its background and extent the working distance of the imaging system. The underwater imaging system is required to have the ability to image in low light level conditions, as well as the ability to eliminate the back scattering effect, which means that the receiver has to be high-speed external trigger function, high resolution, high sensitivity, low noise, higher gain dynamic range. When it comes to an intensifier, the noise characteristics directly restrict the observation effect and range of the imaging system. The background noise may decrease the image contrast and sharpness, even covering the signal making it impossible to recognize the target. So it is quite important to investigate the noise characteristics of intensifiers. SNR is an important parameter reflecting the noise features of a system. Through the use of underwater laser range-gated imaging prediction model, and according to the linear SNR system theory, the gated imaging noise performance of the present market adopted super second generation and generation Ⅲ intensifiers were theoretically analyzed. Based on the active laser underwater range-gated imaging model, the effect to the system by gated intensifiers and the relationship between the system SNR and MTF were studied. Through theoretical and simulation analysis to the image intensifier background noise and SNR, the different influence on system SNR by super second generation and generation Ⅲ ICCD was obtained. Range-gated system SNR formula was put forward, and compared the different effect influence on the system by using two kind of ICCDs was compared. According to the matlab simulation, a detailed analysis was carried out theoretically. All the work in this paper lays a theoretical foundation to further eliminating back scattering effect, improving image SNR, designing and manufacturing higher performance underwater range-gated imaging systems.

Recovery of Degraded-Beyond-Recognition 19th Century Daguerreotypes with Rapid High Dynamic Range Elemental X-ray Fluorescence Imaging of Mercury L Emission.

PubMed

Kozachuk, Madalena S; Sham, Tsun-Kong; Martin, Ronald R; Nelson, Andrew J; Coulthard, Ian; McElhone, John P

2018-06-22

A daguerreotype image, the first commercialized photographic process, is composed of silver-mercury, and often silver-mercury-gold amalgam particles on the surface of a silver-coated copper plate. Specular and diffuse reflectance of light from these image particles produces the range of gray tones that typify these 19 th century images. By mapping the mercury distribution with rapid-scanning, synchrotron-based micro-X-ray fluorescence (μ-XRF) imaging, full portraits, which to the naked eye are obscured entirely by extensive corrosion, can be retrieved in a non-invasive, non-contact, and non-destructive manner. This work furthers the chemical understanding regarding the production of these images and suggests that mercury is retained in the image particles despite surface degradation. Most importantly, μ-XRF imaging provides curators with an image recovery method for degraded daguerreotypes, even if the artifact's condition is beyond traditional conservation treatments.

Modification of microneedles using inkjet printing

NASA Astrophysics Data System (ADS)

Boehm, R. D.; Miller, P. R.; Hayes, S. L.; Monteiro-Riviere, N. A.; Narayan, R. J.

2011-06-01

In this study, biodegradable acid anhydride copolymer microneedles containing quantum dots were fabricated by means of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing. Nanoindentation was performed to obtain the hardness and the Young's modulus of the biodegradable acid anhydride copolymer. Imaging of quantum dots within porcine skin was accomplished by means of multiphoton microscopy. Our results suggest that the combination of visible light dynamic mask micro-stereolithography-micromolding and inkjet printing enables fabrication of solid biodegradable microneedles with a wide range of geometries as well as a wide range of pharmacologic agent compositions.

Acousto-Optic Processing of 2-D Signals Using Temporal and Spatial Integration.

DTIC Science & Technology

1983-05-31

Documents includes data on: Architectures; Coherence Properties of Pulsed Laser Diodes; Acousto - optic device data; Dynamic Range Issues; Image correlation; Synthetic aperture radar; 2-D Fourier transform; and Moments.

Light-pollution measurement with the Wide-field all-sky image analyzing monitoring system

NASA Astrophysics Data System (ADS)

Vítek, S.

2017-07-01

The purpose of this experiment was to measure light pollution in the capital of Czech Republic, Prague. As a measuring instrument is used calibrated consumer level digital single reflex camera with IR cut filter, therefore, the paper reports results of measuring and monitoring of the light pollution in the wavelength range of 390 - 700 nm, which most affects visual range astronomy. Combining frames of different exposure times made with a digital camera coupled with fish-eye lens allow to create high dynamic range images, contain meaningful values, so such a system can provide absolute values of the sky brightness.

In situ two-dimensional imaging quick-scanning XAFS with pixel array detector.

PubMed

Tanida, Hajime; Yamashige, Hisao; Orikasa, Yuki; Oishi, Masatsugu; Takanashi, Yu; Fujimoto, Takahiro; Sato, Kenji; Takamatsu, Daiko; Murayama, Haruno; Arai, Hajime; Matsubara, Eiichiro; Uchimoto, Yoshiharu; Ogumi, Zempachi

2011-11-01

Quick-scanning X-ray absorption fine structure (XAFS) measurements were performed in transmission mode using a PILATUS 100K pixel array detector (PAD). The method can display a two-dimensional image for a large area of the order of a centimetre with a spatial resolution of 0.2 mm at each energy point in the XAFS spectrum. The time resolution of the quick-scanning method ranged from 10 s to 1 min per spectrum depending on the energy range. The PAD has a wide dynamic range and low noise, so the obtained spectra have a good signal-to-noise ratio.

Photographer: JPL P-21744 C Range: 4.2 million kilometers (2.6 million miles) In this image of

NASA Technical Reports Server (NTRS)

1979-01-01

Photographer: JPL P-21744 C Range: 4.2 million kilometers (2.6 million miles) In this image of Europa acquired by Voyager 2, global scale dark streaks are becoming visible. Europa, the size of the earth's moon, is apparently covered by water ice as indicated by ground based spectrometers and its brightness. The central longitude of this view is 235 west. Bright rayed impact craters which are abundant on ancient Ganymede and Callisto would easily be visible at this range. The suggestion is that Europa's surface is young and that the streaks are reflections of currently active internal dynamic processes.

Importing super-resolution imaging into nanoscale puzzles of materials dynamics

NASA Astrophysics Data System (ADS)

King, John; Tsang, Chi Hang Boyce; Wilson, William; Granick, Steve

2014-03-01

A limitation of the exciting recent advances in sub-diffraction microscopy is that they focus on imaging rather than dynamical changes. We are engaged in extending this technique beyond the usual biological applications to address materials problems instead. To this end, we employ stimulated emission depletion (STED) microscopy, which relies on selectively turning off fluorescence emitters through stimulated emission, allowing only a small subset of emitters to be detected, such that the excitation spot size can be downsized to tens of nanometers. By coupling the STED excitation scheme to fluorescence correlation spectroscopy (FCS), diffusive processes are studied with nanoscale resolution. Here, we demonstrate the benefits of such experimental capabilities in a diverse range of complex systems, ranging from the diffusion of nano-objects in crowded 3D environments to the study of polymer diffusion on 2D surfaces.

Nonlinear spatio-temporal filtering of dynamic PET data using a four-dimensional Gaussian filter and expectation-maximization deconvolution

NASA Astrophysics Data System (ADS)

Floberg, J. M.; Holden, J. E.

2013-02-01

We introduce a method for denoising dynamic PET data, spatio-temporal expectation-maximization (STEM) filtering, that combines four-dimensional Gaussian filtering with EM deconvolution. The initial Gaussian filter suppresses noise at a broad range of spatial and temporal frequencies and EM deconvolution quickly restores the frequencies most important to the signal. We aim to demonstrate that STEM filtering can improve variance in both individual time frames and in parametric images without introducing significant bias. We evaluate STEM filtering with a dynamic phantom study, and with simulated and human dynamic PET studies of a tracer with reversible binding behaviour, [C-11]raclopride, and a tracer with irreversible binding behaviour, [F-18]FDOPA. STEM filtering is compared to a number of established three and four-dimensional denoising methods. STEM filtering provides substantial improvements in variance in both individual time frames and in parametric images generated with a number of kinetic analysis techniques while introducing little bias. STEM filtering does bias early frames, but this does not affect quantitative parameter estimates. STEM filtering is shown to be superior to the other simple denoising methods studied. STEM filtering is a simple and effective denoising method that could be valuable for a wide range of dynamic PET applications.

Dynamic flat panel detector versus image intensifier in cardiac imaging: dose and image quality

NASA Astrophysics Data System (ADS)

Vano, E.; Geiger, B.; Schreiner, A.; Back, C.; Beissel, J.

2005-12-01

The practical aspects of the dosimetric and imaging performance of a digital x-ray system for cardiology procedures were evaluated. The system was configured with an image intensifier (II) and later upgraded to a dynamic flat panel detector (FD). Entrance surface air kerma (ESAK) to phantoms of 16, 20, 24 and 28 cm of polymethyl methacrylate (PMMA) and the image quality of a test object were measured. Images were evaluated directly on the monitor and with numerical methods (noise and signal-to-noise ratio). Information contained in the DICOM header for dosimetry audit purposes was also tested. ESAK values per frame (or kerma rate) for the most commonly used cine and fluoroscopy modes for different PMMA thicknesses and for field sizes of 17 and 23 cm for II, and 20 and 25 cm for FD, produced similar results in the evaluated system with both technologies, ranging between 19 and 589 µGy/frame (cine) and 5 and 95 mGy min-1 (fluoroscopy). Image quality for these dose settings was better for the FD version. The 'study dosimetric report' is comprehensive, and its numerical content is sufficiently accurate. There is potential in the future to set those systems with dynamic FD to lower doses than are possible in the current II versions, especially for digital cine runs, or to benefit from improved image quality.

Some Processing and Dynamic-Range Issues in Side-Scan Sonar Work

NASA Astrophysics Data System (ADS)

Asper, V. L.; Caruthers, J. W.

2007-05-01

Often side-scan sonar data are collected in such a way that they afford little opportunity to do more than simply display them as images. These images are often limited in dynamic range and stored only in an 8-bit tiff format of numbers representing less than true intensity values. Furthermore, there is little prior knowledge during a survey of the best range in which to set those eight bits. This can result in clipped strong targets and/or the depth of shadows so that the bits that can be recovered from the image are not fully representative of target or bottom backscatter strengths. Several top-of-the-line sonars do have a means of logging high-bit-rate digital data (sometimes only as an option), but only dedicated specialists pay much attention to such data, if they record them at all. Most users of side-scan sonars are interested only in the images. Discussed in this paper are issues related to storing and processing of high-bit-rate digital data to preserve their integrity for future enhanced, after- the-fact use and ability to recover actual backscatter strengths. This papers discusses issues in the use high-bit- rate, digital side-scan sonar data. This work was supported by the Office of Naval Research, Code 321OA, and the Naval Oceanographic Office, Mine Warfare Program.

Progress in sensor performance testing, modeling and range prediction using the TOD method: an overview

NASA Astrophysics Data System (ADS)

Bijl, Piet; Hogervorst, Maarten A.; Toet, Alexander

2017-05-01

The Triangle Orientation Discrimination (TOD) methodology includes i) a widely applicable, accurate end-to-end EO/IR sensor test, ii) an image-based sensor system model and iii) a Target Acquisition (TA) range model. The method has been extensively validated against TA field performance for a wide variety of well- and under-sampled imagers, systems with advanced image processing techniques such as dynamic super resolution and local adaptive contrast enhancement, and sensors showing smear or noise drift, for both static and dynamic test stimuli and as a function of target contrast. Recently, significant progress has been made in various directions. Dedicated visual and NIR test charts for lab and field testing are available and thermal test benches are on the market. Automated sensor testing using an objective synthetic human observer is within reach. Both an analytical and an image-based TOD model have recently been developed and are being implemented in the European Target Acquisition model ECOMOS and in the EOSTAR TDA. Further, the methodology is being applied for design optimization of high-end security camera systems. Finally, results from a recent perception study suggest that DRI ranges for real targets can be predicted by replacing the relevant distinctive target features by TOD test patterns of the same characteristic size and contrast, enabling a new TA modeling approach. This paper provides an overview.

Readout models for BaFBr0.85I0.15:Eu image plates

NASA Astrophysics Data System (ADS)

Stoeckl, M.; Solodov, A. A.

2018-06-01

The linearity of the photostimulated luminescence process makes repeated image-plate scanning a viable technique to extract a more dynamic range. In order to obtain a response estimate, two semi-empirical models for the readout fading of an image plate are introduced; they relate the depth distribution of activated photostimulated luminescence centers within an image plate to the recorded signal. Model parameters are estimated from image-plate scan series with BAS-MS image plates and the Typhoon FLA 7000 scanner for the hard x-ray image-plate diagnostic over a collection of experiments providing x-ray energy spectra whose approximate shape is a double exponential.

A new imaging method for understanding chemical dynamics: efficient slice imaging using an in-vacuum pixel detector.

PubMed

Jungmann, J H; Gijsbertsen, A; Visser, J; Visschers, J; Heeren, R M A; Vrakking, M J J

2010-10-01

The implementation of the Timepix complementary metal oxide semiconductor pixel detector in velocity map slice imaging is presented. This new detector approach eliminates the need for gating the imaging detector. In time-of-flight mode, the detector returns the impact position and the time-of-flight of charged particles with 12.5 ns resolution and a dynamic range of about 100 μs. The implementation of the Timepix detector in combination with a microchannel plate additionally allows for high spatial resolution information via center-of-mass centroiding. Here, the detector was applied to study the photodissociation of NO(2) at 452 nm. The energy resolution observed in the experiment was ΔE/E=0.05 and is limited by the experimental setup rather than by the detector assembly. All together, this new compact detector assembly is well-suited for slice imaging and is a promising tool for imaging studies in atomic and molecular physics research.

Test–retest repeatability of human speech biomarkers from static and real-time dynamic magnetic resonance imaging

PubMed Central

Töger, Johannes; Sorensen, Tanner; Somandepalli, Krishna; Toutios, Asterios; Lingala, Sajan Goud; Narayanan, Shrikanth; Nayak, Krishna

2017-01-01

Static anatomical and real-time dynamic magnetic resonance imaging (RT-MRI) of the upper airway is a valuable method for studying speech production in research and clinical settings. The test–retest repeatability of quantitative imaging biomarkers is an important parameter, since it limits the effect sizes and intragroup differences that can be studied. Therefore, this study aims to present a framework for determining the test–retest repeatability of quantitative speech biomarkers from static MRI and RT-MRI, and apply the framework to healthy volunteers. Subjects (n = 8, 4 females, 4 males) are imaged in two scans on the same day, including static images and dynamic RT-MRI of speech tasks. The inter-study agreement is quantified using intraclass correlation coefficient (ICC) and mean within-subject standard deviation (σe). Inter-study agreement is strong to very strong for static measures (ICC: min/median/max 0.71/0.89/0.98, σe: 0.90/2.20/6.72 mm), poor to strong for dynamic RT-MRI measures of articulator motion range (ICC: 0.26/0.75/0.90, σe: 1.6/2.5/3.6 mm), and poor to very strong for velocities (ICC: 0.21/0.56/0.93, σe: 2.2/4.4/16.7 cm/s). In conclusion, this study characterizes repeatability of static and dynamic MRI-derived speech biomarkers using state-of-the-art imaging. The introduced framework can be used to guide future development of speech biomarkers. Test–retest MRI data are provided free for research use. PMID:28599561

Revealing glacier flow and surge dynamics from animated satellite image sequences: examples from the Karakoram

NASA Astrophysics Data System (ADS)

Paul, F.

2015-11-01

Although animated images are very popular on the internet, they have so far found only limited use for glaciological applications. With long time series of satellite images becoming increasingly available and glaciers being well recognized for their rapid changes and variable flow dynamics, animated sequences of multiple satellite images reveal glacier dynamics in a time-lapse mode, making the otherwise slow changes of glacier movement visible and understandable to the wider public. For this study, animated image sequences were created for four regions in the central Karakoram mountain range over a 25-year time period (1990-2015) from freely available image quick-looks of orthorectified Landsat scenes. The animations play automatically in a web browser and reveal highly complex patterns of glacier flow and surge dynamics that are difficult to obtain by other methods. In contrast to other regions, surging glaciers in the Karakoram are often small (10 km2 or less), steep, debris-free, and advance for several years to decades at relatively low annual rates (about 100 m a-1). These characteristics overlap with those of non-surge-type glaciers, making a clear identification difficult. However, as in other regions, the surging glaciers in the central Karakoram also show sudden increases of flow velocity and mass waves travelling down glacier. The surges of individual glaciers are generally out of phase, indicating a limited climatic control on their dynamics. On the other hand, nearly all other glaciers in the region are either stable or slightly advancing, indicating balanced or even positive mass budgets over the past few decades.

Multi-scale volumetric cell and tissue imaging based on optical projection tomography (Conference Presentation)

NASA Astrophysics Data System (ADS)

Ban, Sungbea; Cho, Nam Hyun; Ryu, Yongjae; Jung, Sunwoo; Vavilin, Andrey; Min, Eunjung; Jung, Woonggyu

2016-04-01

Optical projection tomography is a new optical imaging method for visualizing small biological specimens in three dimension. The most important advantage of OPT is to fill the gap between MRI and confocal microscope for the specimen having the range of 1-10 mm. Thus, it has been mainly used for whole-mount small animals and developmental study since this imaging modality was developed. The ability of OPT delivering anatomical and functional information of relatively large tissue in 3D has made it a promising platform in biomedical research. Recently, the potential of OPT spans its coverage to cellular scale. Even though there are increasing demand to obtain better understanding of cellular dynamics, only few studies to visualize cellular structure, shape, size and functional morphology over tissue has been investigated in existing OPT system due to its limited field of view. In this study, we develop a novel optical imaging system for 3D cellular imaging with OPT integrated with dynamic focusing technique. Our tomographic setup has great potential to be used for identifying cell characteristic in tissue because it can provide selective contrast on dynamic focal plane allowing for fluorescence as well as absorption. While the dominant contrast of optical imaging technique is to use the fluorescence for detecting certain target only, the newly developed OPT system will offer considerable advantages over currently available method when imaging cellar molecular dynamics by permitting contrast variation. By achieving multi-contrast, it is expected for this new imaging system to play an important role in delivering better cytological information to pathologist.

A digital-signal-processor-based optical tomographic system for dynamic imaging of joint diseases

NASA Astrophysics Data System (ADS)

Lasker, Joseph M.

Over the last decade, optical tomography (OT) has emerged as viable biomedical imaging modality. Various imaging systems have been developed that are employed in preclinical as well as clinical studies, mostly targeting breast imaging, brain imaging, and cancer related studies. Of particular interest are so-called dynamic imaging studies where one attempts to image changes in optical properties and/or physiological parameters as they occur during a system perturbation. To successfully perform dynamic imaging studies, great effort is put towards system development that offers increasingly enhanced signal-to-noise performance at ever shorter data acquisition times, thus capturing high fidelity tomographic data within narrower time periods. Towards this goal, I have developed in this thesis a dynamic optical tomography system that is, unlike currently available analog instrumentation, based on digital data acquisition and filtering techniques. At the core of this instrument is a digital signal processor (DSP) that collects, collates, and processes the digitized data set. Complementary protocols between the DSP and a complex programmable logic device synchronizes the sampling process and organizes data flow. Instrument control is implemented through a comprehensive graphical user interface which integrates automated calibration, data acquisition, and signal post-processing. Real-time data is generated at frame rates as high as 140 Hz. An extensive dynamic range (˜190 dB) accommodates a wide scope of measurement geometries and tissue types. Performance analysis demonstrates very low system noise (˜1 pW rms noise equivalent power), excellent signal precision (˜0.04%--0.2%) and long term system stability (˜1% over 40 min). Experiments on tissue phantoms validate spatial and temporal accuracy of the system. As a potential new application of dynamic optical imaging I present the first application of this method to use vascular hemodynamics as a means of characterizing joint diseases, especially effects of rheumatoid arthritis (RA) in the proximal interphalangeal finger joints. Using a dual-wavelength tomographic imaging system and previously implemented reconstruction scheme, I have performed initial dynamic imaging case studies on healthy volunteers and patients diagnosed with RA. These studies support our hypothesis that differences in the vascular and metabolic reactivity exist between affected and unaffected joints and can be used for diagnostic purposes.

Electromagnetic behavior of spatial terahertz wave modulators based on reconfigurable micromirror gratings in Littrow configuration.

PubMed

Kappa, Jan; Schmitt, Klemens M; Rahm, Marco

2017-08-21

Efficient, high speed spatial modulators with predictable performance are a key element in any coded aperture terahertz imaging system. For spectroscopy, the modulators must also provide a broad modulation frequency range. In this study, we numerically analyze the electromagnetic behavior of a dynamically reconfigurable spatial terahertz wave modulator based on a micromirror grating in Littrow configuration. We show that such a modulator can modulate terahertz radiation over a wide frequency range from 1.7 THz to beyond 3 THz at a modulation depth of more than 0.6. As a specific example, we numerically simulated coded aperture imaging of an object with binary transmissive properties and successfully reconstructed the image.

Experimental investigations of ablation stream interaction dynamics in tungsten wire arrays: Interpenetration, magnetic field advection, and ion deflection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swadling, G. F.; Lebedev, S. V.; Hall, G. N.

2016-05-01

Experiments have been carried out to investigate the collisional dynamics of ablation streams produced by cylindrical wire array z-pinches. A combination of laser interferometric imaging, Thomson scattering, and Faraday rotation imaging has been used to make a range of measurements of the temporal evolution of various plasma and flow parameters. Our paper presents a summary of previously published data, drawing together a range of different measurements in order to give an overview of the key results. The paper focuses mainly on the results of experiments with tungsten wire arrays. Early interferometric imaging measurements are reviewed, then more recent Thomson scatteringmore » measurements are discussed; these measurements provided the first direct evidence of ablation stream interpenetration in a wire array experiment. Combining the data from these experiments gives a view of the temporal evolution of the tungsten stream collisional dynamics. In the final part of the paper, we present new experimental measurements made using an imaging Faraday rotation diagnostic. Our experiments investigated the structure of magnetic fields near the array axis directly; the presence of a magnetic field has previously been inferred based on Thomson scattering measurements of ion deflection near the array axis. Although the Thomson and Faraday measurements are not in full quantitative agreement, the Faraday data do qualitatively supports the conjecture that the observed deflections are induced by a static toroidal magnetic field, which has been advected to the array axis by the ablation streams. It is likely that detailed modeling will be needed in order to fully understand the dynamics observed in the experiment.« less

Experimental investigations of ablation stream interaction dynamics in tungsten wire arrays: Interpenetration, magnetic field advection, and ion deflection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swadling, G. F.; Lebedev, S. V.; Hall, G. N.

2016-05-15

Experiments have been carried out to investigate the collisional dynamics of ablation streams produced by cylindrical wire array z-pinches. A combination of laser interferometric imaging, Thomson scattering, and Faraday rotation imaging has been used to make a range of measurements of the temporal evolution of various plasma and flow parameters. This paper presents a summary of previously published data, drawing together a range of different measurements in order to give an overview of the key results. The paper focuses mainly on the results of experiments with tungsten wire arrays. Early interferometric imaging measurements are reviewed, then more recent Thomson scatteringmore » measurements are discussed; these measurements provided the first direct evidence of ablation stream interpenetration in a wire array experiment. Combining the data from these experiments gives a view of the temporal evolution of the tungsten stream collisional dynamics. In the final part of the paper, we present new experimental measurements made using an imaging Faraday rotation diagnostic. These experiments investigated the structure of magnetic fields near the array axis directly; the presence of a magnetic field has previously been inferred based on Thomson scattering measurements of ion deflection near the array axis. Although the Thomson and Faraday measurements are not in full quantitative agreement, the Faraday data do qualitatively supports the conjecture that the observed deflections are induced by a static toroidal magnetic field, which has been advected to the array axis by the ablation streams. It is likely that detailed modeling will be needed in order to fully understand the dynamics observed in the experiment.« less

Microradiography with Semiconductor Pixel Detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jakubek, Jan; Cejnarova, Andrea; Dammer, Jiri

High resolution radiography (with X-rays, neutrons, heavy charged particles, ...) often exploited also in tomographic mode to provide 3D images stands as a powerful imaging technique for instant and nondestructive visualization of fine internal structure of objects. Novel types of semiconductor single particle counting pixel detectors offer many advantages for radiation imaging: high detection efficiency, energy discrimination or direct energy measurement, noiseless digital integration (counting), high frame rate and virtually unlimited dynamic range. This article shows the application and potential of pixel detectors (such as Medipix2 or TimePix) in different fields of radiation imaging.

The Lick Observatory image-dissector scanner.

NASA Technical Reports Server (NTRS)

Robinson, L. B.; Wampler, E. J.

1972-01-01

A scanner that uses an image dissector to scan the output screen of an image tube has proven to be a sensitive and linear detector for faint astronomical spectra. The image-tube phosphor screen acts as a short-term storage element and allows the system to approach the performance of an ideal multichannel photon counter. Pulses resulting from individual photons, emitted from the output phosphor and detected by the image dissector, trigger an amplifier-discriminator and are counted in a 24-bit, 4096-word circulating memory. Aspects of system performance are discussed, giving attention to linearity, dynamic range, sensitivity, stability, and scattered light properties.

Miniaturized GPS/MEMS IMU integrated board

NASA Technical Reports Server (NTRS)

Lin, Ching-Fang (Inventor)

2012-01-01

This invention documents the efforts on the research and development of a miniaturized GPS/MEMS IMU integrated navigation system. A miniaturized GPS/MEMS IMU integrated navigation system is presented; Laser Dynamic Range Imager (LDRI) based alignment algorithm for space applications is discussed. Two navigation cameras are also included to measure the range and range rate which can be integrated into the GPS/MEMS IMU system to enhance the navigation solution.

Photometric Calibration of Consumer Video Cameras

NASA Technical Reports Server (NTRS)

Suggs, Robert; Swift, Wesley, Jr.

2007-01-01

Equipment and techniques have been developed to implement a method of photometric calibration of consumer video cameras for imaging of objects that are sufficiently narrow or sufficiently distant to be optically equivalent to point or line sources. Heretofore, it has been difficult to calibrate consumer video cameras, especially in cases of image saturation, because they exhibit nonlinear responses with dynamic ranges much smaller than those of scientific-grade video cameras. The present method not only takes this difficulty in stride but also makes it possible to extend effective dynamic ranges to several powers of ten beyond saturation levels. The method will likely be primarily useful in astronomical photometry. There are also potential commercial applications in medical and industrial imaging of point or line sources in the presence of saturation.This development was prompted by the need to measure brightnesses of debris in amateur video images of the breakup of the Space Shuttle Columbia. The purpose of these measurements is to use the brightness values to estimate relative masses of debris objects. In most of the images, the brightness of the main body of Columbia was found to exceed the dynamic ranges of the cameras. A similar problem arose a few years ago in the analysis of video images of Leonid meteors. The present method is a refined version of the calibration method developed to solve the Leonid calibration problem. In this method, one performs an endto- end calibration of the entire imaging system, including not only the imaging optics and imaging photodetector array but also analog tape recording and playback equipment (if used) and any frame grabber or other analog-to-digital converter (if used). To automatically incorporate the effects of nonlinearity and any other distortions into the calibration, the calibration images are processed in precisely the same manner as are the images of meteors, space-shuttle debris, or other objects that one seeks to analyze. The light source used to generate the calibration images is an artificial variable star comprising a Newtonian collimator illuminated by a light source modulated by a rotating variable neutral- density filter. This source acts as a point source, the brightness of which varies at a known rate. A video camera to be calibrated is aimed at this source. Fixed neutral-density filters are inserted in or removed from the light path as needed to make the video image of the source appear to fluctuate between dark and saturated bright. The resulting video-image data are analyzed by use of custom software that determines the integrated signal in each video frame and determines the system response curve (measured output signal versus input brightness). These determinations constitute the calibration, which is thereafter used in automatic, frame-by-frame processing of the data from the video images to be analyzed.

Structure and Dynamics of Dinucleosomes Assessed by Atomic Force Microscopy

DOE PAGES

Filenko, Nina A.; Palets, Dmytro B.; Lyubchenko, Yuri L.

2012-01-01

Dynamics of nucleosomes and their interactions are important for understanding the mechanism of chromatin assembly. Internucleosomal interaction is required for the formation of higher-order chromatin structures. Although H1 histone is critically involved in the process of chromatin assembly, direct internucleosomal interactions contribute to this process as well. To characterize the interactions of nucleosomes within the nucleosome array, we designed a dinucleosome and performed direct AFM imaging. The analysis of the AFM data showed dinucleosomes are very dynamic systems, enabling the nucleosomes to move in a broad range along the DNA template. Di-nucleosomes in close proximity were observed, but their populationmore » was low. The use of the zwitterionic detergent, CHAPS, increased the dynamic range of the di-nucleosome, facilitating the formation of tight di-nucleosomes. The role of CHAPS and similar natural products in chromatin structure and dynamics is also discussed.« less

Research on range-gated laser active imaging seeker

NASA Astrophysics Data System (ADS)

You, Mu; Wang, PengHui; Tan, DongJie

2013-09-01

Compared with other imaging methods such as millimeter wave imaging, infrared imaging and visible light imaging, laser imaging provides both a 2-D array of reflected intensity data as well as 2-D array of range data, which is the most important data for use in autonomous target acquisition .In terms of application, it can be widely used in military fields such as radar, guidance and fuse. In this paper, we present a laser active imaging seeker system based on range-gated laser transmitter and sensor technology .The seeker system presented here consist of two important part, one is laser image system, which uses a negative lens to diverge the light from a pulse laser to flood illuminate a target, return light is collected by a camera lens, each laser pulse triggers the camera delay and shutter. The other is stabilization gimbals, which is designed to be a rotatable structure both in azimuth and elevation angles. The laser image system consists of transmitter and receiver. The transmitter is based on diode pumped solid-state lasers that are passively Q-switched at 532nm wavelength. A visible wavelength was chosen because the receiver uses a Gen III image intensifier tube with a spectral sensitivity limited to wavelengths less than 900nm.The receiver is image intensifier tube's micro channel plate coupled into high sensitivity charge coupled device camera. The image has been taken at range over one kilometer and can be taken at much longer range in better weather. Image frame frequency can be changed according to requirement of guidance with modifiable range gate, The instantaneous field of views of the system was found to be 2×2 deg. Since completion of system integration, the seeker system has gone through a series of tests both in the lab and in the outdoor field. Two different kinds of buildings have been chosen as target, which is located at range from 200m up to 1000m.To simulate dynamic process of range change between missile and target, the seeker system has been placed on the truck vehicle running along the road in an expected speed. The test result shows qualified image and good performance of the seeker system.

Backwards compatible high dynamic range video compression

NASA Astrophysics Data System (ADS)

Dolzhenko, Vladimir; Chesnokov, Vyacheslav; Edirisinghe, Eran A.

2014-02-01

This paper presents a two layer CODEC architecture for high dynamic range video compression. The base layer contains the tone mapped video stream encoded with 8 bits per component which can be decoded using conventional equipment. The base layer content is optimized for rendering on low dynamic range displays. The enhancement layer contains the image difference, in perceptually uniform color space, between the result of inverse tone mapped base layer content and the original video stream. Prediction of the high dynamic range content reduces the redundancy in the transmitted data while still preserves highlights and out-of-gamut colors. Perceptually uniform colorspace enables using standard ratedistortion optimization algorithms. We present techniques for efficient implementation and encoding of non-uniform tone mapping operators with low overhead in terms of bitstream size and number of operations. The transform representation is based on human vision system model and suitable for global and local tone mapping operators. The compression techniques include predicting the transform parameters from previously decoded frames and from already decoded data for current frame. Different video compression techniques are compared: backwards compatible and non-backwards compatible using AVC and HEVC codecs.

Face recognition based on matching of local features on 3D dynamic range sequences

NASA Astrophysics Data System (ADS)

Echeagaray-Patrón, B. A.; Kober, Vitaly

2016-09-01

3D face recognition has attracted attention in the last decade due to improvement of technology of 3D image acquisition and its wide range of applications such as access control, surveillance, human-computer interaction and biometric identification systems. Most research on 3D face recognition has focused on analysis of 3D still data. In this work, a new method for face recognition using dynamic 3D range sequences is proposed. Experimental results are presented and discussed using 3D sequences in the presence of pose variation. The performance of the proposed method is compared with that of conventional face recognition algorithms based on descriptors.

Lock-in imaging with synchronous digital mirror demodulation

NASA Astrophysics Data System (ADS)

Bush, Michael G.

2010-04-01

Lock-in imaging enables high contrast imaging in adverse conditions by exploiting a modulated light source and homodyne detection. We report results on a patent pending lock-in imaging system fabricated from commercial-off-theshelf parts utilizing standard cameras and a spatial light modulator. By leveraging the capabilities of standard parts we are able to present a low cost, high resolution, high sensitivity camera with applications in search and rescue, friend or foe identification (IFF), and covert surveillance. Different operating modes allow the same instrument to be utilized for dual band multispectral imaging or high dynamic range imaging, increasing the flexibility in different operational settings.

A blood-mimicking fluid for particle image velocimetry with silicone vascular models

NASA Astrophysics Data System (ADS)

Yousif, Majid Y.; Holdsworth, David W.; Poepping, Tamie L.

2011-03-01

For accurate particle image velocimetry measurements in hemodynamics studies, it is important to use a fluid with a refractive index ( n) matching that of the vascular models (phantoms) and ideally a dynamic viscosity matching human blood. In this work, a blood-mimicking fluid (BMF) composed of water, glycerol, and sodium iodide was formulated for a range of refractive indices to match most common silicone elastomers ( n = 1.40-1.43) and with corresponding dynamic viscosity within the average cited range of healthy human blood (4.4 ± 0.5 cP). Both refractive index and viscosity were attained at room temperature (22.2 ± 0.2°C), which eliminates the need for a temperature-control system. An optimally matched BMF, suitable for use in a vascular phantom ( n = 1.4140 ± 0.0008, Sylgard 184), was demonstrated with composition (by weight) of 47.38% water, 36.94% glycerol (44:56 glycerol-water ratio), and 15.68% sodium iodide salt, resulting in a dynamic viscosity of 4 .31 ± 0 .03 cP.

Complex regression Doppler optical coherence tomography

NASA Astrophysics Data System (ADS)

Elahi, Sahar; Gu, Shi; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.

2018-04-01

We introduce a new method to measure Doppler shifts more accurately and extend the dynamic range of Doppler optical coherence tomography (OCT). The two-point estimate of the conventional Doppler method is replaced with a regression that is applied to high-density B-scans in polar coordinates. We built a high-speed OCT system using a 1.68-MHz Fourier domain mode locked laser to acquire high-density B-scans (16,000 A-lines) at high enough frame rates (˜100 fps) to accurately capture the dynamics of the beating embryonic heart. Flow phantom experiments confirm that the complex regression lowers the minimum detectable velocity from 12.25 mm / s to 374 μm / s, whereas the maximum velocity of 400 mm / s is measured without phase wrapping. Complex regression Doppler OCT also demonstrates higher accuracy and precision compared with the conventional method, particularly when signal-to-noise ratio is low. The extended dynamic range allows monitoring of blood flow over several stages of development in embryos without adjusting the imaging parameters. In addition, applying complex averaging recovers hidden features in structural images.

Experimental analysis of quasi-static and dynamic fracture initiation toughness of gy4 armor steel material

NASA Astrophysics Data System (ADS)

Ren, Peng; Guo, Zitao

Quasi-static and dynamic fracture initiation toughness of gy4 armour steel material are investigated using three point bend specimen. The modified split Hopkinson pressure bar (SHPB) apparatus with digital image correlation (DIC) system is applied to dynamic loading experiments. Full-field deformation measurements are obtained by using DIC to elucidate on the strain fields associated with the mechanical response. A series of experiments are conducted at different strain rate ranging from 10-3 s-1 to 103 s-1, and the loading rate on the fracture initiation toughness is investigated. Specially, the scanning electron microscope imaging technique is used to investigate the fracture failure micromechanism of fracture surfaces. The gy4 armour steel material fracture toughness is found to be sensitive to strain rate and higher for dynamic loading as compared to quasi-static loading. This work is supported by National Nature Science Foundation under Grant 51509115.

Dynamical effects in Bragg coherent x-ray diffraction imaging of finite crystals

NASA Astrophysics Data System (ADS)

Shabalin, A. G.; Yefanov, O. M.; Nosik, V. L.; Bushuev, V. A.; Vartanyants, I. A.

2017-08-01

We present simulations of Bragg coherent x-ray diffractive imaging (CXDI) data from finite crystals in the frame of the dynamical theory of x-ray diffraction. The developed approach is based on a numerical solution of modified Takagi-Taupin equations and can be applied for modeling of a broad range of x-ray diffraction experiments with finite three-dimensional crystals of arbitrary shape also in the presence of strain. We performed simulations for nanocrystals of a cubic and hemispherical shape of different sizes and provided a detailed analysis of artifacts in the Bragg CXDI reconstructions introduced by the dynamical diffraction. Based on our theoretical analysis we developed an analytical procedure to treat effects of refraction and absorption in the reconstruction. Our results elucidate limitations for the kinematical approach in the Bragg CXDI and suggest a natural criterion to distinguish between kinematical and dynamical cases in coherent x-ray diffraction on a finite crystal.

Effect of tone mapping operators on visual attention deployment

NASA Astrophysics Data System (ADS)

Narwaria, Manish; Perreira Da Silva, Matthieu; Le Callet, Patrick; Pepion, Romuald

2012-10-01

High Dynamic Range (HDR) images/videos require the use of a tone mapping operator (TMO) when visualized on Low Dynamic Range (LDR) displays. From an artistic intention point of view, TMOs are not necessarily transparent and might induce different behavior to view the content. In this paper, we investigate and quantify how TMOs modify visual attention (VA). To that end both objective and subjective tests in the form of eye-tracking experiments have been conducted on several still image content that have been processed by 11 different TMOs. Our studies confirm that TMOs can indeed modify human attention and fixation behavior significantly. Therefore our studies suggest that VA needs consideration for evaluating the overall perceptual impact of TMOs on HDR content. Since the existing studies so far have only considered the quality or aesthetic appeal angle, this study brings in a new perspective regarding the importance of VA in HDR content processing for visualization on LDR displays.

Active Sensor for Microwave Tissue Imaging with Bias-Switched Arrays.

PubMed

Foroutan, Farzad; Nikolova, Natalia K

2018-05-06

A prototype of a bias-switched active sensor was developed and measured to establish the achievable dynamic range in a new generation of active arrays for microwave tissue imaging. The sensor integrates a printed slot antenna, a low-noise amplifier (LNA) and an active mixer in a single unit, which is sufficiently small to enable inter-sensor separation distance as small as 12 mm. The sensor’s input covers the bandwidth from 3 GHz to 7.5 GHz. Its output intermediate frequency (IF) is 30 MHz. The sensor is controlled by a simple bias-switching circuit, which switches ON and OFF the bias of the LNA and the mixer simultaneously. It was demonstrated experimentally that the dynamic range of the sensor, as determined by its ON and OFF states, is 109 dB and 118 dB at resolution bandwidths of 1 kHz and 100 Hz, respectively.

New amorphous-silicon image sensor for x-ray diagnostic medical imaging applications

NASA Astrophysics Data System (ADS)

Weisfield, Richard L.; Hartney, Mark A.; Street, Robert A.; Apte, Raj B.

1998-07-01

This paper introduces new high-resolution amorphous Silicon (a-Si) image sensors specifically configured for demonstrating film-quality medical x-ray imaging capabilities. The devices utilizes an x-ray phosphor screen coupled to an array of a-Si photodiodes for detecting visible light, and a-Si thin-film transistors (TFTs) for connecting the photodiodes to external readout electronics. We have developed imagers based on a pixel size of 127 micrometer X 127 micrometer with an approximately page-size imaging area of 244 mm X 195 mm, and array size of 1,536 data lines by 1,920 gate lines, for a total of 2.95 million pixels. More recently, we have developed a much larger imager based on the same pixel pattern, which covers an area of approximately 406 mm X 293 mm, with 2,304 data lines by 3,200 gate lines, for a total of nearly 7.4 million pixels. This is very likely to be the largest image sensor array and highest pixel count detector fabricated on a single substrate. Both imagers connect to a standard PC and are capable of taking an image in a few seconds. Through design rule optimization we have achieved a light sensitive area of 57% and optimized quantum efficiency for x-ray phosphor output in the green part of the spectrum, yielding an average quantum efficiency between 500 and 600 nm of approximately 70%. At the same time, we have managed to reduce extraneous leakage currents on these devices to a few fA per pixel, which allows for very high dynamic range to be achieved. We have characterized leakage currents as a function of photodiode bias, time and temperature to demonstrate high stability over these large sized arrays. At the electronics level, we have adopted a new generation of low noise, charge- sensitive amplifiers coupled to 12-bit A/D converters. Considerable attention was given to reducing electronic noise in order to demonstrate a large dynamic range (over 4,000:1) for medical imaging applications. Through a combination of low data lines capacitance, readout amplifier design, optimized timing, and noise cancellation techniques, we achieve 1,000e to 2,000e of noise for the page size and large size arrays, respectively. This allows for true 12-bit performance and quantum limited images over a wide range of x-ray exposures. Various approaches to reducing line correlated noise have been implemented and will be discussed. Images documenting the improved performance will be presented. Avenues for improvement are under development, including higher resolution 97 micrometer pixel imagers, further improvements in detective quantum efficiency, and characterization of dynamic behavior.

Acousto-optic RF signal acquisition system

NASA Astrophysics Data System (ADS)

Bloxham, Laurence H.

1990-09-01

This paper describes the architecture and performance of a prototype Acousto-Optic RF Signal Acquisition System designed to intercept, automatically identify, and track communication signals in the VHF band. The system covers 28.0 to 92.0 MHz with five manually selectable, dual conversion; 12.8 MHZ bandwidth front ends. An acousto-optic spectrum analyzer (AOSA) implemented using a tellurium dioxide (Te02) Bragg cell is used to channelize the 12.8 MHz pass band into 512 25 KHz channels. Polarization switching is used to suppress optical noise. Excellent isolation and dynamic range are achieved by using a linear array of 512 custom 40/50 micron fiber optic cables to collect the light at the focal plane of the AOSA and route the light to individual photodetectors. The photodetectors are operated in the photovoltaic mode to compress the greater than 60 dB input optical dynamic range into an easily processed electrical signal. The 512 signals are multiplexed and processed as a line in a video image by a customized digital image processing system. The image processor simultaneously analyzes the channelized signal data and produces a classical waterfall display.

Using dynamic programming to improve fiducial marker localization

NASA Astrophysics Data System (ADS)

Wan, Hanlin; Ge, Jiajia; Parikh, Parag

2014-04-01

Fiducial markers are used in a wide range of medical imaging applications. In radiation therapy, they are often implanted near tumors and used as motion surrogates that are tracked with fluoroscopy. We propose a novel and robust method based on dynamic programming (DP) for retrospectively localizing radiopaque fiducial markers in fluoroscopic images. Our method was compared to template matching (TM) algorithms on 407 data sets from 24 patients. We found that the performance of TM varied dramatically depending on the template used (ranging from 47% to 92% of data sets with a mean error <1 mm). DP by itself requires no template and performed as well as the best TM method, localizing the markers in 91% of the data sets with a mean error <1 mm. Finally, by combining DP and TM, we were able to localize the markers in 99% of the data sets with a mean error <1 mm, regardless of the template used. Our results show that DP can be a powerful tool for analyzing tumor motion, capable of accurately locating fiducial markers in fluoroscopic images regardless of marker type, shape, and size.

Cognition in action: imaging brain/body dynamics in mobile humans.

PubMed

Gramann, Klaus; Gwin, Joseph T; Ferris, Daniel P; Oie, Kelvin; Jung, Tzyy-Ping; Lin, Chin-Teng; Liao, Lun-De; Makeig, Scott

2011-01-01

We have recently developed a mobile brain imaging method (MoBI), that allows for simultaneous recording of brain and body dynamics of humans actively behaving in and interacting with their environment. A mobile imaging approach was needed to study cognitive processes that are inherently based on the use of human physical structure to obtain behavioral goals. This review gives examples of the tight coupling between human physical structure with cognitive processing and the role of supraspinal activity during control of human stance and locomotion. Existing brain imaging methods for actively behaving participants are described and new sensor technology allowing for mobile recordings of different behavioral states in humans is introduced. Finally, we review recent work demonstrating the feasibility of a MoBI system that was developed at the Swartz Center for Computational Neuroscience at the University of California, San Diego, demonstrating the range of behavior that can be investigated with this method.

Electron-tracking Compton gamma-ray camera for small animal and phantom imaging

NASA Astrophysics Data System (ADS)

Kabuki, Shigeto; Kimura, Hiroyuki; Amano, Hiroo; Nakamoto, Yuji; Kubo, Hidetoshi; Miuchi, Kentaro; Kurosawa, Shunsuke; Takahashi, Michiaki; Kawashima, Hidekazu; Ueda, Masashi; Okada, Tomohisa; Kubo, Atsushi; Kunieda, Etuso; Nakahara, Tadaki; Kohara, Ryota; Miyazaki, Osamu; Nakazawa, Tetsuo; Shirahata, Takashi; Yamamoto, Etsuji; Ogawa, Koichi; Togashi, Kaori; Saji, Hideo; Tanimori, Toru

2010-11-01

We have developed an electron-tracking Compton camera (ETCC) for medical use. Our ETCC has a wide energy dynamic range (200-1300 keV) and wide field of view (3 sr), and thus has potential for advanced medical use. To evaluate the ETCC, we imaged the head (brain) and bladder of mice that had been administered with F-18-FDG. We also imaged the head and thyroid gland of mice using double tracers of F-18-FDG and I-131 ions.

Development of CCD imaging sensors for space applications, phase 1

NASA Technical Reports Server (NTRS)

Antcliffe, G. A.

1975-01-01

The results of an experimental investigation to develop a large area charge coupled device (CCD) imager for space photography applications are described. Details of the design and processing required to achieve 400 X 400 imagers are presented together with a discussion of the optical characterization techniques developed for this program. A discussion of several aspects of large CCD performance is given with detailed test reports. The areas covered include dark current, uniformity of optical response, square wave amplitude response, spectral responsivity and dynamic range.

Development and testing of the EVS 2000 enhanced vision system

NASA Astrophysics Data System (ADS)

Way, Scott P.; Kerr, Richard; Imamura, Joe J.; Arnoldy, Dan; Zeylmaker, Richard; Zuro, Greg

2003-09-01

An effective enhanced vision system must operate over a broad spectral range in order to offer a pilot an optimized scene that includes runway background as well as airport lighting and aircraft operations. The large dynamic range of intensities of these images is best handled with separate imaging sensors. The EVS 2000 is a patented dual-band Infrared Enhanced Vision System (EVS) utilizing image fusion concepts to provide a single image from uncooled infrared imagers in both the LWIR and SWIR. The system is designed to provide commercial and corporate airline pilots with improved situational awareness at night and in degraded weather conditions. A prototype of this system was recently fabricated and flown on the Boeing Advanced Technology Demonstrator 737-900 aircraft. This paper will discuss the current EVS 2000 concept, show results taken from the Boeing Advanced Technology Demonstrator program, and discuss future plans for EVS systems.

Partial scan artifact reduction (PSAR) for the assessment of cardiac perfusion in dynamic phase-correlated CT.

PubMed

Stenner, Philip; Schmidt, Bernhard; Bruder, Herbert; Allmendinger, Thomas; Haberland, Ulrike; Flohr, Thomas; Kachelriess, Marc

2009-12-01

Cardiac CT achieves its high temporal resolution by lowering the scan range from 2pi to pi plus fan angle (partial scan). This, however, introduces CT-value variations, depending on the angular position of the pi range. These partial scan artifacts are of the order of a few HU and prevent the quantitative evaluation of perfusion measurements. The authors present the new algorithm partial scan artifact reduction (PSAR) that corrects a dynamic phase-correlated scan without a priori information. In general, a full scan does not suffer from partial scan artifacts since all projections in [0, 2pi] contribute to the data. To maintain the optimum temporal resolution and the phase correlation, PSAR creates an artificial full scan pn(AF) by projectionwise averaging a set of neighboring partial scans pn(P) from the same perfusion examination (typically N approximately 30 phase-correlated partial scans distributed over 20 s and n = 1, ..., N). Corresponding to the angular range of each partial scan, the authors extract virtual partial scans pn(V) from the artificial full scan pn(AF). A standard reconstruction yields the corresponding images fn(P), fn(AF), and fn(V). Subtracting the virtual partial scan image fn(V) from the artificial full scan image fn(AF) yields an artifact image that can be used to correct the original partial scan image: fn(C) = fn(P) - fn(V) + fn(AF), where fn(C) is the corrected image. The authors evaluated the effects of scattered radiation on the partial scan artifacts using simulated and measured water phantoms and found a strong correlation. The PSAR algorithm has been validated with a simulated semianthropomorphic heart phantom and with measurements of a dynamic biological perfusion phantom. For the stationary phantoms, real full scans have been performed to provide theoretical reference values. The improvement in the root mean square errors between the full and the partial scans with respect to the errors between the full and the corrected scans is up to 54% for the simulations and 90% for the measurements. The phase-correlated data now appear accurate enough for a quantitative analysis of cardiac perfusion.

Single-image hard-copy display of the spine utilizing digital radiography

NASA Astrophysics Data System (ADS)

Artz, Dorothy S.; Janchar, Timothy; Milzman, David; Freedman, Matthew T.; Mun, Seong K.

1997-04-01

Regions of the entire spine contain a wide latitude of tissue densities within the imaged field of view presenting a problem for adequate radiological evaluation. With screen/film technology, the optimal technique for one area of the radiograph is sub-optimal for another area. Computed radiography (CR) with its inherent wide dynamic range, has been shown to be better than screen/film for lateral cervical spine imaging, but limitations are still present with standard image processing. By utilizing a dynamic range control (DRC) algorithm based on unsharp masking and signal transformation prior to gradation and frequency processing within the CR system, more vertebral bodies can be seen on a single hard copy display of the lateral cervical, thoracic, and thoracolumbar examinations. Examinations of the trauma cross-table lateral cervical spine, lateral thoracic spine, and lateral thoracolumbar spine were collected on live patient using photostimulable storage phosphor plates, the Fuji FCR 9000 reader, and the Fuji AC-3 computed radiography reader. Two images were produced from a single exposure; one with standard image processing and the second image with the standard process and the additional DRC algorithm. Both sets were printed from a Fuji LP 414 laser printer. Two different DRC algorithms were applied depending on which portion of the spine was not well visualized. One algorithm increased optical density and the second algorithm decreased optical density. The resultant image pairs were then reviewed by a panel of radiologists. Images produced with the additional DRC algorithm demonstrated improved visualization of previously 'under exposed' and 'over exposed' regions within the same image. Where lung field had previously obscured bony detail of the lateral thoracolumbar spine due to 'over exposure,' the image with the DRC applied to decrease the optical density allowed for easy visualization of the entire area of interest. For areas of the lateral cervical spine and lateral thoracic spine that typically have a low optical density value, the DRC algorithm used increased the optical density over that region improving visualization of C7-T2 and T11-L2 vertebral bodies; critical in trauma radiography. Emergency medicine physicians also reviewing the lateral cervical spine images were able to clear 37% of the DRC images compared to 30% of the non-DRC images for removal of the cervical collar. The DRC processed images reviewed by the physicians do not have a typical screen/film appearance; however, these different images were preferred for the three examinations in this study. This method of image processing after being tested and accepted, is in use clinically at Georgetown University Medical Center Department of Radiology for the following examinations: cervical spine, lateral thoracic spine, lateral thoracolumbar examinations, facial bones, shoulder, sternum, feet and portable chest. Computed radiography imaging of the spine is improved with the addition of histogram equalization known as dynamic range control (DRC). More anatomical structures are visualized on a single hard copy display.

Image Accumulation in Pixel Detector Gated by Late External Trigger Signal and its Application in Imaging Activation Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jakubek, J.; Cejnarova, A.; Platkevic, M.

Single quantum counting pixel detectors of Medipix type are starting to be used in various radiographic applications. Compared to standard devices for digital imaging (such as CCDs or CMOS sensors) they present significant advantages: direct conversion of radiation to electric signal, energy sensitivity, noiseless image integration, unlimited dynamic range, absolute linearity. In this article we describe usage of the pixel device TimePix for image accumulation gated by late trigger signal. Demonstration of the technique is given on imaging coincidence instrumental neutron activation analysis (Imaging CINAA). This method allows one to determine concentration and distribution of certain preselected element in anmore » inspected sample.« less

Infrared Camera Diagnostic for Heat Flux Measurements on NSTX

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. Mastrovito; R. Maingi; H.W. Kugel

2003-03-25

An infrared imaging system has been installed on NSTX (National Spherical Torus Experiment) at the Princeton Plasma Physics Laboratory to measure the surface temperatures on the lower divertor and center stack. The imaging system is based on an Indigo Alpha 160 x 128 microbolometer camera with 12 bits/pixel operating in the 7-13 {micro}m range with a 30 Hz frame rate and a dynamic temperature range of 0-700 degrees C. From these data and knowledge of graphite thermal properties, the heat flux is derived with a classic one-dimensional conduction model. Preliminary results of heat flux scaling are reported.

Analysis and Processing the 3D-Range-Image-Data for Robot Monitoring

NASA Astrophysics Data System (ADS)

Kohoutek, Tobias

2008-09-01

Industrial robots are commonly used for physically stressful jobs in complex environments. In any case collisions with heavy and high dynamic machines need to be prevented. For this reason the operational range has to be monitored precisely, reliably and meticulously. The advantage of the SwissRanger® SR-3000 is that it delivers intensity images and 3D-information simultaneously of the same scene that conveniently allows 3D-monitoring. Due to that fact automatic real time collision prevention within the robots working space is possible by working with 3D-coordinates.

Dynamic programming in parallel boundary detection with application to ultrasound intima-media segmentation.

PubMed

Zhou, Yuan; Cheng, Xinyao; Xu, Xiangyang; Song, Enmin

2013-12-01

Segmentation of carotid artery intima-media in longitudinal ultrasound images for measuring its thickness to predict cardiovascular diseases can be simplified as detecting two nearly parallel boundaries within a certain distance range, when plaque with irregular shapes is not considered. In this paper, we improve the implementation of two dynamic programming (DP) based approaches to parallel boundary detection, dual dynamic programming (DDP) and piecewise linear dual dynamic programming (PL-DDP). Then, a novel DP based approach, dual line detection (DLD), which translates the original 2-D curve position to a 4-D parameter space representing two line segments in a local image segment, is proposed to solve the problem while maintaining efficiency and rotation invariance. To apply the DLD to ultrasound intima-media segmentation, it is imbedded in a framework that employs an edge map obtained from multiplication of the responses of two edge detectors with different scales and a coupled snake model that simultaneously deforms the two contours for maintaining parallelism. The experimental results on synthetic images and carotid arteries of clinical ultrasound images indicate improved performance of the proposed DLD compared to DDP and PL-DDP, with respect to accuracy and efficiency. Copyright © 2013 Elsevier B.V. All rights reserved.

Rational design of reversible fluorescent probes for live-cell imaging and quantification of fast glutathione dynamics.

PubMed

Umezawa, Keitaro; Yoshida, Masafumi; Kamiya, Mako; Yamasoba, Tatsuya; Urano, Yasuteru

2017-03-01

Alterations in glutathione (GSH) homeostasis are associated with a variety of diseases and cellular functions, and therefore, real-time live-cell imaging and quantification of GSH dynamics are important for understanding pathophysiological processes. However, existing fluorescent probes are unsuitable for these purposes due to their irreversible fluorogenic mechanisms or slow reaction rates. In this work, we have successfully overcome these problems by establishing a design strategy inspired by Mayr's work on nucleophilic reaction kinetics. The synthesized probes exhibit concentration-dependent, reversible and rapid absorption/fluorescence changes (t 1/2  = 620 ms at [GSH] = 1 mM), as well as appropriate K d values (1-10 mM: within the range of intracellular GSH concentrations). We also developed FRET-based ratiometric probes, and demonstrated that they are useful for quantifying GSH concentration in various cell types and also for real-time live-cell imaging of GSH dynamics with temporal resolution of seconds.

Rational design of reversible fluorescent probes for live-cell imaging and quantification of fast glutathione dynamics

NASA Astrophysics Data System (ADS)

Umezawa, Keitaro; Yoshida, Masafumi; Kamiya, Mako; Yamasoba, Tatsuya; Urano, Yasuteru

2017-03-01

Alterations in glutathione (GSH) homeostasis are associated with a variety of diseases and cellular functions, and therefore, real-time live-cell imaging and quantification of GSH dynamics are important for understanding pathophysiological processes. However, existing fluorescent probes are unsuitable for these purposes due to their irreversible fluorogenic mechanisms or slow reaction rates. In this work, we have successfully overcome these problems by establishing a design strategy inspired by Mayr's work on nucleophilic reaction kinetics. The synthesized probes exhibit concentration-dependent, reversible and rapid absorption/fluorescence changes (t1/2 = 620 ms at [GSH] = 1 mM), as well as appropriate Kd values (1-10 mM: within the range of intracellular GSH concentrations). We also developed FRET-based ratiometric probes, and demonstrated that they are useful for quantifying GSH concentration in various cell types and also for real-time live-cell imaging of GSH dynamics with temporal resolution of seconds.

Solar Flare Dynamic Microwave Imaging with EOVSA

NASA Astrophysics Data System (ADS)

Gary, D. E.; Chen, B.; Nita, G. M.; Fleishman, G. D.; Yu, S.; White, S. M.; Hurford, G. J.; McTiernan, J. M.

2017-12-01

The Expanded Owens Valley Solar Array (EOVSA) is both an expansion of our existing solar array and serves as a prototype for a much larger future project, the Frequency Agile Solar Radiotelescope (FASR). EOVSA is now complete, and is producing daily imaging of the full solar disk, including active regions and solar radio bursts at hundreds of frequencies in the range 2.8-18 GHz. We present highlights of the 1-s-cadence dynamic imaging spectroscropy of radio bursts we have obtained to date, along with deeper analysis of multi-wavelength observations and modeling of a well-observed burst. These observations are revealing the full life-cycle of the trapped population of high-energy electrons, from their initial acceleration and subsequent energy-evolution to their eventual decay through escape and thermalization. All of our data are being made available for download in both quick-look image form and in the form of the community-standard CASA measurement sets for subsequent imaging and analysis.

Development of a high-speed VCSEL OCT system for real-time imaging of conscious patients larynx using a hand-held probe (Conference Presentation)

NASA Astrophysics Data System (ADS)

Rangarajan, Swathi; Chou, Li-Dek; Coughlan, Carolyn; Sharma, Giriraj; Wong, Brian J. F.; Ramalingam, Tirunelveli S.

2016-02-01

Fourier domain optical coherence tomography (FD-OCT) is a noninvasive imaging modality that has previously been used to image the human larynx. However, differences in anatomical geometry and short imaging range of conventional OCT limits its application in a clinical setting. In order to address this issue, we have developed a gradient-index (GRIN) lens rod-based hand-held probe in conjunction with a long imaging range 200 kHz Vertical-Cavity Surface Emitting Lasers (VCSEL) swept-source optical coherence tomography (SS-OCT) system for high speed real-time imaging of the human larynx in an office setting. This hand-held probe is designed to have a long and dynamically tunable working distance to accommodate the differences in anatomical geometry of human test subjects. A nominal working distance (~6 cm) of the probe is selected to have a lateral resolution <100 um within a depth of focus of 6.4 mm, which covers more than half of the 12 mm imaging range of the VCSEL laser. The maximum lateral scanning range of the probe at 6 cm working distance is approximately 8.4 mm, and imaging an area of 8.5 mm by 8.5 mm is accomplished within a second. Using the above system, we will demonstrate real-time cross-sectional OCT imaging of larynx during phonation in vivo in human and ex-vivo in pig vocal folds.

[In vivo measurement of rabbits brain impedance frequency response and the elementary imaging of EIT].

PubMed

Wu, Xiaoming; Dong, Xiuzhen; Qin, Mingxin; Fu, Feng; Wang, Yuemin; You, Fusheng; Xiang, Haiyan; Liu, Ruigang; Shi, Xuetao

2003-03-01

The in vivo measurements of rabbit brain tissue impedance were taken under both normal and ischemic conditions by using two-electrode measurement method in the frequency range from 0.1 Hz to 1 MHz. The dynamic images about the resistivity of cerebral ischemia were reconstructed based on a 16-electrode system. The results of in vivo measurement showed that the ratio of impedance increased can be as high as 75% at frequencies lower than 10 Hz. In the range from 1 KHz to 1 MHz, the ratio showed a constant value of 15%. The electrical impedance tomography (EIT) images obtained suggested that the regions of impedance changes highly correspond to the position of ischemia. It is confirmed that the brain function changes caused by local deficiency of blood can be detected and imaged by EIT method.

Ultrasound Imaging Velocimetry: a review

NASA Astrophysics Data System (ADS)

Poelma, Christian

2017-01-01

Whole-field velocity measurement techniques based on ultrasound imaging (a.k.a. `ultrasound imaging velocimetry' or `echo-PIV') have received significant attention from the fluid mechanics community in the last decade, in particular because of their ability to obtain velocity fields in flows that elude characterisation by conventional optical methods. In this review, an overview is given of the history, typical components and challenges of these techniques. The basic principles of ultrasound image formation are summarised, as well as various techniques to estimate flow velocities; the emphasis is on correlation-based techniques. Examples are given for a wide range of applications, including in vivo cardiovascular flow measurements, the characterisation of sediment transport and the characterisation of complex non-Newtonian fluids. To conclude, future opportunities are identified. These encompass not just optimisation of the accuracy and dynamic range, but also extension to other application areas.

Self-Organization of Spatio-Temporal Hierarchy via Learning of Dynamic Visual Image Patterns on Action Sequences

PubMed Central

Jung, Minju; Hwang, Jungsik; Tani, Jun

2015-01-01

It is well known that the visual cortex efficiently processes high-dimensional spatial information by using a hierarchical structure. Recently, computational models that were inspired by the spatial hierarchy of the visual cortex have shown remarkable performance in image recognition. Up to now, however, most biological and computational modeling studies have mainly focused on the spatial domain and do not discuss temporal domain processing of the visual cortex. Several studies on the visual cortex and other brain areas associated with motor control support that the brain also uses its hierarchical structure as a processing mechanism for temporal information. Based on the success of previous computational models using spatial hierarchy and temporal hierarchy observed in the brain, the current report introduces a novel neural network model for the recognition of dynamic visual image patterns based solely on the learning of exemplars. This model is characterized by the application of both spatial and temporal constraints on local neural activities, resulting in the self-organization of a spatio-temporal hierarchy necessary for the recognition of complex dynamic visual image patterns. The evaluation with the Weizmann dataset in recognition of a set of prototypical human movement patterns showed that the proposed model is significantly robust in recognizing dynamically occluded visual patterns compared to other baseline models. Furthermore, an evaluation test for the recognition of concatenated sequences of those prototypical movement patterns indicated that the model is endowed with a remarkable capability for the contextual recognition of long-range dynamic visual image patterns. PMID:26147887

Self-Organization of Spatio-Temporal Hierarchy via Learning of Dynamic Visual Image Patterns on Action Sequences.

PubMed

Jung, Minju; Hwang, Jungsik; Tani, Jun

2015-01-01

It is well known that the visual cortex efficiently processes high-dimensional spatial information by using a hierarchical structure. Recently, computational models that were inspired by the spatial hierarchy of the visual cortex have shown remarkable performance in image recognition. Up to now, however, most biological and computational modeling studies have mainly focused on the spatial domain and do not discuss temporal domain processing of the visual cortex. Several studies on the visual cortex and other brain areas associated with motor control support that the brain also uses its hierarchical structure as a processing mechanism for temporal information. Based on the success of previous computational models using spatial hierarchy and temporal hierarchy observed in the brain, the current report introduces a novel neural network model for the recognition of dynamic visual image patterns based solely on the learning of exemplars. This model is characterized by the application of both spatial and temporal constraints on local neural activities, resulting in the self-organization of a spatio-temporal hierarchy necessary for the recognition of complex dynamic visual image patterns. The evaluation with the Weizmann dataset in recognition of a set of prototypical human movement patterns showed that the proposed model is significantly robust in recognizing dynamically occluded visual patterns compared to other baseline models. Furthermore, an evaluation test for the recognition of concatenated sequences of those prototypical movement patterns indicated that the model is endowed with a remarkable capability for the contextual recognition of long-range dynamic visual image patterns.

SSBD: a database of quantitative data of spatiotemporal dynamics of biological phenomena

PubMed Central

Tohsato, Yukako; Ho, Kenneth H. L.; Kyoda, Koji; Onami, Shuichi

2016-01-01

Motivation: Rapid advances in live-cell imaging analysis and mathematical modeling have produced a large amount of quantitative data on spatiotemporal dynamics of biological objects ranging from molecules to organisms. There is now a crucial need to bring these large amounts of quantitative biological dynamics data together centrally in a coherent and systematic manner. This will facilitate the reuse of this data for further analysis. Results: We have developed the Systems Science of Biological Dynamics database (SSBD) to store and share quantitative biological dynamics data. SSBD currently provides 311 sets of quantitative data for single molecules, nuclei and whole organisms in a wide variety of model organisms from Escherichia coli to Mus musculus. The data are provided in Biological Dynamics Markup Language format and also through a REST API. In addition, SSBD provides 188 sets of time-lapse microscopy images from which the quantitative data were obtained and software tools for data visualization and analysis. Availability and Implementation: SSBD is accessible at http://ssbd.qbic.riken.jp. Contact: sonami@riken.jp PMID:27412095

SSBD: a database of quantitative data of spatiotemporal dynamics of biological phenomena.

PubMed

Tohsato, Yukako; Ho, Kenneth H L; Kyoda, Koji; Onami, Shuichi

2016-11-15

Rapid advances in live-cell imaging analysis and mathematical modeling have produced a large amount of quantitative data on spatiotemporal dynamics of biological objects ranging from molecules to organisms. There is now a crucial need to bring these large amounts of quantitative biological dynamics data together centrally in a coherent and systematic manner. This will facilitate the reuse of this data for further analysis. We have developed the Systems Science of Biological Dynamics database (SSBD) to store and share quantitative biological dynamics data. SSBD currently provides 311 sets of quantitative data for single molecules, nuclei and whole organisms in a wide variety of model organisms from Escherichia coli to Mus musculus The data are provided in Biological Dynamics Markup Language format and also through a REST API. In addition, SSBD provides 188 sets of time-lapse microscopy images from which the quantitative data were obtained and software tools for data visualization and analysis. SSBD is accessible at http://ssbd.qbic.riken.jp CONTACT: sonami@riken.jp. © The Author 2016. Published by Oxford University Press.

Nonlinear Optical Image Processing with Bacteriorhodopsin Films

NASA Technical Reports Server (NTRS)

Downie, John D.; Deiss, Ron (Technical Monitor)

1994-01-01

The transmission properties of some bacteriorhodopsin film spatial light modulators are uniquely suited to allow nonlinear optical image processing operations to be applied to images with multiplicative noise characteristics. A logarithmic amplitude transmission feature of the film permits the conversion of multiplicative noise to additive noise, which may then be linearly filtered out in the Fourier plane of the transformed image. The bacteriorhodopsin film displays the logarithmic amplitude response for write beam intensities spanning a dynamic range greater than 2.0 orders of magnitude. We present experimental results demonstrating the principle and capability for several different image and noise situations, including deterministic noise and speckle. Using the bacteriorhodopsin film, we successfully filter out image noise from the transformed image that cannot be removed from the original image.

Nonlinear coherent optical image processing using logarithmic transmittance of bacteriorhodopsin films

NASA Astrophysics Data System (ADS)

Downie, John D.

1995-08-01

The transmission properties of some bacteriorhodopsin-film spatial light modulators are uniquely suited to allow nonlinear optical image-processing operations to be applied to images with multiplicative noise characteristics. A logarithmic amplitude-transmission characteristic of the film permits the conversion of multiplicative noise to additive noise, which may then be linearly filtered out in the Fourier plane of the transformed image. I present experimental results demonstrating the principle and the capability for several different image and noise situations, including deterministic noise and speckle. The bacteriorhodopsin film studied here displays the logarithmic transmission response for write intensities spanning a dynamic range greater than 2 orders of magnitude.

Nonlinear Coherent Optical Image Processing Using Logarithmic Transmittance of Bacteriorhodopsin Films

NASA Technical Reports Server (NTRS)

Downie, John D.

1995-01-01

The transmission properties of some bacteriorhodopsin-film spatial light modulators are uniquely suited to allow nonlinear optical image-processing operations to be applied to images with multiplicative noise characteristics. A logarithmic amplitude-transmission characteristic of the film permits the conversion of multiplicative noise to additive noise, which may then be linearly filtered out in the Fourier plane of the transformed image. I present experimental results demonstrating the principle and the capability for several different image and noise situations, including deterministic noise and speckle. The bacteriorhodopsin film studied here displays the logarithmic transmission response for write intensities spanning a dynamic range greater than 2 orders of magnitude.

An improved schlieren method for measurement and automatic reconstruction of the far-field focal spot

PubMed Central

Wang, Zhengzhou; Hu, Bingliang; Yin, Qinye

2017-01-01

The schlieren method of measuring far-field focal spots offers many advantages at the Shenguang III laser facility such as low cost and automatic laser-path collimation. However, current methods of far-field focal spot measurement often suffer from low precision and efficiency when the final focal spot is merged manually, thereby reducing the accuracy of reconstruction. In this paper, we introduce an improved schlieren method to construct the high dynamic-range image of far-field focal spots and improve the reconstruction accuracy and efficiency. First, a detection method based on weak light beam sampling and magnification imaging was designed; images of the main and side lobes of the focused laser irradiance in the far field were obtained using two scientific CCD cameras. Second, using a self-correlation template matching algorithm, a circle the same size as the schlieren ball was dug from the main lobe cutting image and used to change the relative region of the main lobe cutting image within a 100×100 pixel region. The position that had the largest correlation coefficient between the side lobe cutting image and the main lobe cutting image when a circle was dug was identified as the best matching point. Finally, the least squares method was used to fit the center of the side lobe schlieren small ball, and the error was less than 1 pixel. The experimental results show that this method enables the accurate, high-dynamic-range measurement of a far-field focal spot and automatic image reconstruction. Because the best matching point is obtained through image processing rather than traditional reconstruction methods based on manual splicing, this method is less sensitive to the efficiency of focal-spot reconstruction and thus offers better experimental precision. PMID:28207758

Comparing methods for analysis of biomedical hyperspectral image data

NASA Astrophysics Data System (ADS)

Leavesley, Silas J.; Sweat, Brenner; Abbott, Caitlyn; Favreau, Peter F.; Annamdevula, Naga S.; Rich, Thomas C.

2017-02-01

Over the past 2 decades, hyperspectral imaging technologies have been adapted to address the need for molecule-specific identification in the biomedical imaging field. Applications have ranged from single-cell microscopy to whole-animal in vivo imaging and from basic research to clinical systems. Enabling this growth has been the availability of faster, more effective hyperspectral filtering technologies and more sensitive detectors. Hence, the potential for growth of biomedical hyperspectral imaging is high, and many hyperspectral imaging options are already commercially available. However, despite the growth in hyperspectral technologies for biomedical imaging, little work has been done to aid users of hyperspectral imaging instruments in selecting appropriate analysis algorithms. Here, we present an approach for comparing the effectiveness of spectral analysis algorithms by combining experimental image data with a theoretical "what if" scenario. This approach allows us to quantify several key outcomes that characterize a hyperspectral imaging study: linearity of sensitivity, positive detection cut-off slope, dynamic range, and false positive events. We present results of using this approach for comparing the effectiveness of several common spectral analysis algorithms for detecting weak fluorescent protein emission in the midst of strong tissue autofluorescence. Results indicate that this approach should be applicable to a very wide range of applications, allowing a quantitative assessment of the effectiveness of the combined biology, hardware, and computational analysis for detecting a specific molecular signature.

Speckle noise reduction in digital holography by slightly rotating the object

NASA Astrophysics Data System (ADS)

Herrera-Ramirez, Jorge; Hincapie-Zuluaga, Diego Andrés; Garcia-Sucerquia, Jorge

2016-12-01

This work shows the realization of speckle reduction in the numerical reconstruction of digitally recorded holograms by the superposition of multiple slightly rotated digital holographic images of the object. The superposition of T uncorrelated holographic images reduces the contrast of the speckle noise of the image following the expected 1/√{T} law. The effect of the method on the borders of the resulting image is evaluated by quantifying the utilization of the dynamic range or the contrast between the white and black areas of a regular die. Experimental results validate the feasibility of the proposed method.

Real-Time High-Dynamic Range Texture Mapping

DTIC Science & Technology

2001-01-01

the renderings produced by radiosity and global illumination algorithms. As a particular example, Greg Ward’s RADIANCE synthetic imaging system [32...in soft- ware only. [26] presented a technique for performing Ward’s tone reproduction algo- rithm interactively to visualize radiosity solutions

Adaptive texture filtering for defect inspection in ultrasound images

NASA Astrophysics Data System (ADS)

Zmola, Carl; Segal, Andrew C.; Lovewell, Brian; Nash, Charles

1993-05-01

The use of ultrasonic imaging to analyze defects and characterize materials is critical in the development of non-destructive testing and non-destructive evaluation (NDT/NDE) tools for manufacturing. To develop better quality control and reliability in the manufacturing environment advanced image processing techniques are useful. For example, through the use of texture filtering on ultrasound images, we have been able to filter characteristic textures from highly-textured C-scan images of materials. The materials have highly regular characteristic textures which are of the same resolution and dynamic range as other important features within the image. By applying texture filters and adaptively modifying their filter response, we have examined a family of filters for removing these textures.

Material characterization and defect inspection in ultrasound images

NASA Astrophysics Data System (ADS)

Zmola, Carl; Segal, Andrew C.; Lovewell, Brian; Mahdavieh, Jacob; Ross, Joseph; Nash, Charles

1992-08-01

The use of ultrasonic imaging to analyze defects and characterize materials is critical in the development of non-destructive testing and non-destructive evaluation (NDT/NDE) tools for manufacturing. To develop better quality control and reliability in the manufacturing environment advanced image processing techniques are useful. For example, through the use of texture filtering on ultrasound images, we have been able to filter characteristic textures from highly textured C-scan images of materials. The materials have highly regular characteristic textures which are of the same resolution and dynamic range as other important features within the image. By applying texture filters and adaptively modifying their filter response, we have examined a family of filters for removing these textures.

Filter methods to preserve local contrast and to avoid artifacts in gamut mapping

NASA Astrophysics Data System (ADS)

Meili, Marcel; Küpper, Dennis; Barańczuk, Zofia; Caluori, Ursina; Simon, Klaus

2010-01-01

Contrary to high dynamic range imaging, the preservation of details and the avoidance of artifacts is not explicitly considered in popular color management systems. An effective way to overcome these difficulties is image filtering. In this paper we investigate several image filter concepts for detail preservation as part of a practical gamut mapping strategy. In particular we define four concepts including various image filters and check their performance with a psycho-visual test. Additionally, we compare our performance evaluation to two image quality measures with emphasis on local contrast. Surprisingly, the most simple filter concept performs highly efficient and achieves an image quality which is comparable to the more established but slower methods.

Optimization of sampling pattern and the design of Fourier ptychographic illuminator.

PubMed

Guo, Kaikai; Dong, Siyuan; Nanda, Pariksheet; Zheng, Guoan

2015-03-09

Fourier ptychography (FP) is a recently developed imaging approach that facilitates high-resolution imaging beyond the cutoff frequency of the employed optics. In the original FP approach, a periodic LED array is used for sample illumination, and therefore, the scanning pattern is a uniform grid in the Fourier space. Such a uniform sampling scheme leads to 3 major problems for FP, namely: 1) it requires a large number of raw images, 2) it introduces the raster grid artefacts in the reconstruction process, and 3) it requires a high-dynamic-range detector. Here, we investigate scanning sequences and sampling patterns to optimize the FP approach. For most biological samples, signal energy is concentrated at low-frequency region, and as such, we can perform non-uniform Fourier sampling in FP by considering the signal structure. In contrast, conventional ptychography perform uniform sampling over the entire real space. To implement the non-uniform Fourier sampling scheme in FP, we have designed and built an illuminator using LEDs mounted on a 3D-printed plastic case. The advantages of this illuminator are threefold in that: 1) it reduces the number of image acquisitions by at least 50% (68 raw images versus 137 in the original FP setup), 2) it departs from the translational symmetry of sampling to solve the raster grid artifact problem, and 3) it reduces the dynamic range of the captured images 6 fold. The results reported in this paper significantly shortened acquisition time and improved quality of FP reconstructions. It may provide new insights for developing Fourier ptychographic imaging platforms and find important applications in digital pathology.

High-Spatial- and High-Temporal-Resolution Dynamic Contrast-enhanced MR Breast Imaging with Sweep Imaging with Fourier Transformation: A Pilot Study

PubMed Central

Benson, John C.; Idiyatullin, Djaudat; Snyder, Angela L.; Snyder, Carl J.; Hutter, Diane; Everson, Lenore I.; Eberly, Lynn E.; Nelson, Michael T.; Garwood, Michael

2015-01-01

Purpose To report the results of sweep imaging with Fourier transformation (SWIFT) magnetic resonance (MR) imaging for diagnostic breast imaging. Materials and Methods Informed consent was obtained from all participants under one of two institutional review board–approved, HIPAA-compliant protocols. Twelve female patients (age range, 19–54 years; mean age, 41.2 years) and eight normal control subjects (age range, 22–56 years; mean age, 43.2 years) enrolled and completed the study from January 28, 2011, to March 5, 2013. Patients had previous lesions that were Breast Imaging Reporting and Data System 4 and 5 based on mammography and/or ultrasonographic imaging. Contrast-enhanced SWIFT imaging was completed by using a 4-T research MR imaging system. Noncontrast studies were completed in the normal control subjects. One of two sized single-breast SWIFT-compatible transceiver coils was used for nine patients and five controls. Three patients and five control subjects used a SWIFT-compatible dual breast coil. Temporal resolution was 5.9–7.5 seconds. Spatial resolution was 1.00 mm isotropic, with later examinations at 0.67 mm isotropic, and dual breast at 1.00 mm or 0.75 mm isotropic resolution. Results Two nonblinded breast radiologists reported SWIFT image findings of normal breast tissue, benign fibroadenomas (six of six lesions), and malignant lesions (10 of 12 lesions) concordant with other imaging modalities and pathologic reports. Two lesions in two patients were not visualized because of coil field of view. The images yielded by SWIFT showed the presence and extent of known breast lesions. Conclusion The SWIFT technique could become an important addition to breast imaging modalities because it provides high spatial resolution at all points during the dynamic contrast-enhanced examination. © RSNA, 2014 PMID:25247405

Indirect flat-panel detector with avalanche gain: Fundamental feasibility investigation for SHARP-AMFPI (scintillator HARP active matrix flat panel imager)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao Wei; Li Dan; Reznik, Alla

2005-09-15

An indirect flat-panel imager (FPI) with avalanche gain is being investigated for low-dose x-ray imaging. It is made by optically coupling a structured x-ray scintillator CsI(Tl) to an amorphous selenium (a-Se) avalanche photoconductor called HARP (high-gain avalanche rushing photoconductor). The final electronic image is read out using an active matrix array of thin film transistors (TFT). We call the proposed detector SHARP-AMFPI (scintillator HARP active matrix flat panel imager). The advantage of the SHARP-AMFPI is its programmable gain, which can be turned on during low dose fluoroscopy to overcome electronic noise, and turned off during high dose radiography to avoidmore » pixel saturation. The purpose of this paper is to investigate the important design considerations for SHARP-AMFPI such as avalanche gain, which depends on both the thickness d{sub Se} and the applied electric field E{sub Se} of the HARP layer. To determine the optimal design parameter and operational conditions for HARP, we measured the E{sub Se} dependence of both avalanche gain and optical quantum efficiency of an 8 {mu}m HARP layer. The results were used in a physical model of HARP as well as a linear cascaded model of the FPI to determine the following x-ray imaging properties in both the avalanche and nonavalanche modes as a function of E{sub Se}: (1) total gain (which is the product of avalanche gain and optical quantum efficiency); (2) linearity; (3) dynamic range; (4) gain nonuniformity resulting from thickness nonuniformity; and (5) effects of direct x-ray interaction in HARP. Our results showed that a HARP layer thickness of 8 {mu}m can provide adequate avalanche gain and sufficient dynamic range for x-ray imaging applications to permit quantum limited operation over the range of exposures needed for radiography and fluoroscopy.« less

UltraTrack: Software for semi-automated tracking of muscle fascicles in sequences of B-mode ultrasound images.

PubMed

Farris, Dominic James; Lichtwark, Glen A

2016-05-01

Dynamic measurements of human muscle fascicle length from sequences of B-mode ultrasound images have become increasingly prevalent in biomedical research. Manual digitisation of these images is time consuming and algorithms for automating the process have been developed. Here we present a freely available software implementation of a previously validated algorithm for semi-automated tracking of muscle fascicle length in dynamic ultrasound image recordings, "UltraTrack". UltraTrack implements an affine extension to an optic flow algorithm to track movement of the muscle fascicle end-points throughout dynamically recorded sequences of images. The underlying algorithm has been previously described and its reliability tested, but here we present the software implementation with features for: tracking multiple fascicles in multiple muscles simultaneously; correcting temporal drift in measurements; manually adjusting tracking results; saving and re-loading of tracking results and loading a range of file formats. Two example runs of the software are presented detailing the tracking of fascicles from several lower limb muscles during a squatting and walking activity. We have presented a software implementation of a validated fascicle-tracking algorithm and made the source code and standalone versions freely available for download. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Geocoronal imaging with Dynamics Explorer

NASA Technical Reports Server (NTRS)

Rairden, R. L.; Frank, L. A.; Craven, J. D.

1986-01-01

The ultraviolet photometer of the University of Iowa spin-scan auroral imaging instrumentation on board Dynamics Explorer-1 has returned numerous hydrogen Lyman alpha images of the geocorona from altitudes of 570 km to 23,300 km (1.09 R sub E to 4.66 R sub E geocentric radial distance). The hydrogen density gradient is shown by a plot of the zenith intensities throughout this range, which decrease to near celestial background values as the spacecraft approaches apogee. Characterizing the upper geocorona as optically thin (single-scattering), the zenith intensity is converted directly to vertical column density. This approximation loses its validity deeper in the geocorona, where the hydrogen is demonstrated to be optically thick in that there is no Lyman alpha limb brightening. Further study of the geocoronal hydrogen distribution will require computer modeling of the radiative transfer.

Imaging system for cardiac planar imaging using a dedicated dual-head gamma camera

DOEpatents

Majewski, Stanislaw [Morgantown, VA; Umeno, Marc M [Woodinville, WA

2011-09-13

A cardiac imaging system employing dual gamma imaging heads co-registered with one another to provide two dynamic simultaneous views of the heart sector of a patient torso. A first gamma imaging head is positioned in a first orientation with respect to the heart sector and a second gamma imaging head is positioned in a second orientation with respect to the heart sector. An adjustment arrangement is capable of adjusting the distance between the separate imaging heads and the angle between the heads. With the angle between the imaging heads set to 180 degrees and operating in a range of 140-159 keV and at a rate of up to 500kHz, the imaging heads are co-registered to produce simultaneous dynamic recording of two stereotactic views of the heart. The use of co-registered imaging heads maximizes the uniformity of detection sensitivity of blood flow in and around the heart over the whole heart volume and minimizes radiation absorption effects. A normalization/image fusion technique is implemented pixel-by-corresponding pixel to increase signal for any cardiac region viewed in two images obtained from the two opposed detector heads for the same time bin. The imaging system is capable of producing enhanced first pass studies, bloodpool studies including planar, gated and non-gated EKG studies, planar EKG perfusion studies, and planar hot spot imaging.

Normal spinal bone marrow in adults: dynamic gadolinium-enhanced MR imaging.

PubMed

Montazel, Jean-Luc; Divine, Marine; Lepage, Eric; Kobeiter, Hicham; Breil, Stephane; Rahmouni, Alain

2003-12-01

To determine the patterns of dynamic enhancement of normal spinal bone marrow in adults at gadolinium-enhanced magnetic resonance (MR) imaging and the changes that occur with aging. Dynamic contrast material-enhanced MR imaging of the thoracolumbar spine was performed in 71 patients. The maximum percentage of enhancement (Emax), enhancement slope, and enhancement washout were determined from bone marrow enhancement time curves (ETCs). The bone marrow signal intensity on T1-weighted spin-echo MR images was qualitatively classified into three grade categories. Quantitative ETC values were correlated with patient age and bone marrow fat content grade. Statistical analysis included mean t test comparison, analysis of variance, and regression analysis of the correlations between age and quantitative MR parameters. Emax, slope, and washout varied widely among the patients. Emax values were obtained within 1 minute after contrast material injection and ranged from 0% to 430%. Emax values were significantly higher in patients younger than 40 years than in those aged 40 years or older (P <.001). These values decreased with increasing age in a logarithmic relationship (r = 0.71). Emax values decreased as fat content increased, but some overlap among the fat content grades was noted. Analysis of variance revealed that Emax was significantly related to age (younger than 40 years vs 40 years or older) (P <.001) and fat content grade (P <.001) but not significantly related to sex. Dynamic contrast-enhanced MR imaging patterns of normal spinal bone marrow are dependent mainly on patient age and fat content.

Combination of CT scanning and fluoroscopy imaging on a flat-panel CT scanner

NASA Astrophysics Data System (ADS)

Grasruck, M.; Gupta, R.; Reichardt, B.; Suess, Ch.; Schmidt, B.; Stierstorfer, K.; Popescu, S.; Brady, T.; Flohr, T.

2006-03-01

We developed and evaluated a prototype flat-panel detector based Volume CT (fpVCT) scanner. The fpVCT scanner consists of a Varian 4030CB a-Si flat-panel detector mounted in a multi slice CT-gantry (Siemens Medical Solutions). It provides a 25 cm field of view with 18 cm z-coverage at the isocenter. In addition to the standard tomographic scanning, fpVCT allows two new scan modes: (1) fluoroscopic imaging from any arbitrary rotation angle, and (2) continuous, time-resolved tomographic scanning of a dynamically changing viewing volume. Fluoroscopic imaging is feasible by modifying the standard CT gantry so that the imaging chain can be oriented along any user-selected rotation angle. Scanning with a stationary gantry, after it has been oriented, is equivalent to a conventional fluoroscopic examination. This scan mode enables combined use of high-resolution tomography and real-time fluoroscopy with a clinically usable field of view in the z direction. The second scan mode allows continuous observation of a timeevolving process such as perfusion. The gantry can be continuously rotated for up to 80 sec, with the rotation time ranging from 3 to 20 sec, to gather projection images of a dynamic process. The projection data, that provides a temporal log of the viewing volume, is then converted into multiple image stacks that capture the temporal evolution of a dynamic process. Studies using phantoms, ex vivo specimens, and live animals have confirmed that these new scanning modes are clinically usable and offer a unique view of the anatomy and physiology that heretofore has not been feasible using static CT scanning. At the current level of image quality and temporal resolution, several clinical applications such a dynamic angiography, tumor enhancement pattern and vascularity studies, organ perfusion, and interventional applications are in reach.

Redox Indicator Mice Stably Expressing Genetically Encoded Neuronal roGFP: Versatile Tools to Decipher Subcellular Redox Dynamics in Neuropathophysiology.

PubMed

Wagener, Kerstin C; Kolbrink, Benedikt; Dietrich, Katharina; Kizina, Kathrin M; Terwitte, Lukas S; Kempkes, Belinda; Bao, Guobin; Müller, Michael

2016-07-01

Reactive oxygen species (ROS) and downstream redox alterations not only mediate physiological signaling but also neuropathology. For long, ROS/redox imaging was hampered by a lack of reliable probes. Genetically encoded redox sensors overcame this gap and revolutionized (sub)cellular redox imaging. Yet, the successful delivery of sensor-coding DNA, which demands transfection/transduction of cultured preparations or stereotaxic microinjections of each subject, remains challenging. By generating transgenic mice, we aimed to overcome limiting cultured preparations, circumvent surgical interventions, and to extend effectively redox imaging to complex and adult preparations. Our redox indicator mice widely express Thy1-driven roGFP1 (reduction-oxidation-sensitive green fluorescent protein 1) in neuronal cytosol or mitochondria. Negative phenotypic effects of roGFP1 were excluded and its proper targeting and functionality confirmed. Redox mapping by ratiometric wide-field imaging reveals most oxidizing conditions in CA3 neurons. Furthermore, mitochondria are more oxidized than cytosol. Cytosolic and mitochondrial roGFP1s reliably report cell endogenous redox dynamics upon metabolic challenge or stimulation. Fluorescence lifetime imaging yields stable, but marginal, response ranges. We therefore developed automated excitation ratiometric 2-photon imaging. It offers superior sensitivity, spatial resolution, and response dynamics. Redox indicator mice enable quantitative analyses of subcellular redox dynamics in a multitude of preparations and at all postnatal stages. This will uncover cell- and compartment-specific cerebral redox signals and their defined alterations during development, maturation, and aging. Cross-breeding with other disease models will reveal molecular details on compartmental redox homeostasis in neuropathology. Combined with ratiometric 2-photon imaging, this will foster our mechanistic understanding of cellular redox signals in their full complexity. Antioxid. Redox Signal. 25, 41-58.

Redox Indicator Mice Stably Expressing Genetically Encoded Neuronal roGFP: Versatile Tools to Decipher Subcellular Redox Dynamics in Neuropathophysiology

PubMed Central

Wagener, Kerstin C.; Kolbrink, Benedikt; Dietrich, Katharina; Kizina, Kathrin M.; Terwitte, Lukas S.; Kempkes, Belinda; Bao, Guobin

2016-01-01

Abstract Aims: Reactive oxygen species (ROS) and downstream redox alterations not only mediate physiological signaling but also neuropathology. For long, ROS/redox imaging was hampered by a lack of reliable probes. Genetically encoded redox sensors overcame this gap and revolutionized (sub)cellular redox imaging. Yet, the successful delivery of sensor-coding DNA, which demands transfection/transduction of cultured preparations or stereotaxic microinjections of each subject, remains challenging. By generating transgenic mice, we aimed to overcome limiting cultured preparations, circumvent surgical interventions, and to extend effectively redox imaging to complex and adult preparations. Results: Our redox indicator mice widely express Thy1-driven roGFP1 (reduction–oxidation-sensitive green fluorescent protein 1) in neuronal cytosol or mitochondria. Negative phenotypic effects of roGFP1 were excluded and its proper targeting and functionality confirmed. Redox mapping by ratiometric wide-field imaging reveals most oxidizing conditions in CA3 neurons. Furthermore, mitochondria are more oxidized than cytosol. Cytosolic and mitochondrial roGFP1s reliably report cell endogenous redox dynamics upon metabolic challenge or stimulation. Fluorescence lifetime imaging yields stable, but marginal, response ranges. We therefore developed automated excitation ratiometric 2-photon imaging. It offers superior sensitivity, spatial resolution, and response dynamics. Innovation and Conclusion: Redox indicator mice enable quantitative analyses of subcellular redox dynamics in a multitude of preparations and at all postnatal stages. This will uncover cell- and compartment-specific cerebral redox signals and their defined alterations during development, maturation, and aging. Cross-breeding with other disease models will reveal molecular details on compartmental redox homeostasis in neuropathology. Combined with ratiometric 2-photon imaging, this will foster our mechanistic understanding of cellular redox signals in their full complexity. Antioxid. Redox Signal. 25, 41–58. PMID:27059697

Phase-slope and phase measurements of tunable CW-THz radiation with terahertz comb for wide-dynamic-range, high-resolution, distance measurement of optically rough object.

PubMed

Yasui, Takeshi; Fujio, Makoto; Yokoyama, Shuko; Araki, Tsutomu

2014-07-14

Phase measurement of continuous-wave terahertz (CW-THz) radiation is a potential tool for direct distance and imaging measurement of optically rough objects due to its high robustness to optical rough surfaces. However, the 2π phase ambiguity in the phase measurement of single-frequency CW-THz radiation limits the dynamic range of the measured distance to the order of the wavelength used. In this article, phase-slope measurement of tunable CW-THz radiation with a THz frequency comb was effectively used to extend the dynamic range up to 1.834 m while maintaining an error of a few tens µm in the distance measurement of an optically rough object. Furthermore, a combination of phase-slope measurement of tunable CW-THz radiation and phase measurement of single-frequency CW-THz radiation enhanced the distance error to a few µm within the dynamic range of 1.834 m without any influence from the 2π phase ambiguity. The proposed method will be a powerful tool for the construction and maintenance of large-scale structures covered with optically rough surfaces.

Real-Time Time-Frequency Two-Dimensional Imaging of Ultrafast Transient Signals in Solid-State Organic Materials

PubMed Central

Takeda, Jun; Ishida, Akihiro; Makishima, Yoshinori; Katayama, Ikufumi

2010-01-01

In this review, we demonstrate a real-time time-frequency two-dimensional (2D) pump-probe imaging spectroscopy implemented on a single shot basis applicable to excited-state dynamics in solid-state organic and biological materials. Using this technique, we could successfully map ultrafast time-frequency 2D transient absorption signals of β-carotene in solid films with wide temporal and spectral ranges having very short accumulation time of 20 ms per unit frame. The results obtained indicate the high potential of this technique as a powerful and unique spectroscopic tool to observe ultrafast excited-state dynamics of organic and biological materials in solid-state, which undergo rapid photodegradation. PMID:22399879

Science Education and Technology: Opportunities to Enhance Student Learning.

ERIC Educational Resources Information Center

Woolsey, Kristina; Bellamy, Rachel

1997-01-01

Describes how technological capabilities such as calculation, imaging, networking, and portability support a range of pedagogical approaches, such as inquiry-based science and dynamic modeling. Includes as examples software products created at Apple Computer and others available in the marketplace. (KDFB)

Spread spectrum phase modulation for coherent X-ray diffraction imaging.

PubMed

Zhang, Xuesong; Jiang, Jing; Xiangli, Bin; Arce, Gonzalo R

2015-09-21

High dynamic range, phase ambiguity and radiation limited resolution are three challenging issues in coherent X-ray diffraction imaging (CXDI), which limit the achievable imaging resolution. This paper proposes a spread spectrum phase modulation (SSPM) method to address the aforementioned problems in a single strobe. The requirements on phase modulator parameters are presented, and a practical implementation of SSPM is discussed via ray optics analysis. Numerical experiments demonstrate the performance of SSPM under the constraint of available X-ray optics fabrication accuracy, showing its potential to real CXDI applications.

Evaluating methods for controlling depth perception in stereoscopic cinematography

NASA Astrophysics Data System (ADS)

Sun, Geng; Holliman, Nick

2009-02-01

Existing stereoscopic imaging algorithms can create static stereoscopic images with perceived depth control function to ensure a compelling 3D viewing experience without visual discomfort. However, current algorithms do not normally support standard Cinematic Storytelling techniques. These techniques, such as object movement, camera motion, and zooming, can result in dynamic scene depth change within and between a series of frames (shots) in stereoscopic cinematography. In this study, we empirically evaluate the following three types of stereoscopic imaging approaches that aim to address this problem. (1) Real-Eye Configuration: set camera separation equal to the nominal human eye interpupillary distance. The perceived depth on the display is identical to the scene depth without any distortion. (2) Mapping Algorithm: map the scene depth to a predefined range on the display to avoid excessive perceived depth. A new method that dynamically adjusts the depth mapping from scene space to display space is presented in addition to an existing fixed depth mapping method. (3) Depth of Field Simulation: apply Depth of Field (DOF) blur effect to stereoscopic images. Only objects that are inside the DOF are viewed in full sharpness. Objects that are far away from the focus plane are blurred. We performed a human-based trial using the ITU-R BT.500-11 Recommendation to compare the depth quality of stereoscopic video sequences generated by the above-mentioned imaging methods. Our results indicate that viewers' practical 3D viewing volumes are different for individual stereoscopic displays and viewers can cope with much larger perceived depth range in viewing stereoscopic cinematography in comparison to static stereoscopic images. Our new dynamic depth mapping method does have an advantage over the fixed depth mapping method in controlling stereo depth perception. The DOF blur effect does not provide the expected improvement for perceived depth quality control in 3D cinematography. We anticipate the results will be of particular interest to 3D filmmaking and real time computer games.

Measuring dynamic membrane fluctuations in cell membrane using quantitative phase imaging (Conference Presentation)

NASA Astrophysics Data System (ADS)

Lee, SangYun; Kim, Kyoohyun; Park, YongKeun

2017-02-01

There is a strong correlation between the dynamic membrane fluctuations and the biomechanical properties of living cells. The dynamic membrane fluctuation consists of submicron displacements, and can be altered by changing the cells' pathophysiological conditions. These results have significant relevance to the understanding of RBC biophysics and pathology, as follows. RBCs must withstand large mechanical deformations during repeated passages through the microvasculature and the fenestrated walls of the splenic sinusoids. This essential ability is diminished with senescence, resulting in physiological destruction of the aging RBCs. Pathological destruction of the red cells, however, occurs in cells affected by a host of diseases such as spherocytosis, malaria, and Sickle cell disease, as RBCs depart from their normal discoid shape and lose their deformability. Therefore, quantifying the RBC deformability insight into a variety of problems regarding the interplay of cell structure, dynamics, and function. Furthermore, the ability to monitor mechanical properties of RBCs is of vital interest in monitoring disease progression or response to treatment as molecular and pharmaceutical approaches for treatment of chronic diseases. Here, we present the measurements of dynamic membrane fluctuations in live cells using quantitative phase imaging techniques. Measuring both the 3-D refractive index maps and the dynamic phase images of live cells are simultaneously measured, from which dynamic membrane fluctuation and deformability of cells are precisely calculated. We also present its applications to various diseases ranging from sickle cell diseases, babesiosis, and to diabetes.

Thermal Texture Generation and 3d Model Reconstruction Using SFM and Gan

NASA Astrophysics Data System (ADS)

Kniaz, V. V.; Mizginov, V. A.

2018-05-01

Realistic 3D models with textures representing thermal emission of the object are widely used in such fields as dynamic scene analysis, autonomous driving, and video surveillance. Structure from Motion (SfM) methods provide a robust approach for the generation of textured 3D models in the visible range. Still, automatic generation of 3D models from the infrared imagery is challenging due to an absence of the feature points and low sensor resolution. Recent advances in Generative Adversarial Networks (GAN) have proved that they can perform complex image-to-image transformations such as a transformation of day to night and generation of imagery in a different spectral range. In this paper, we propose a novel method for generation of realistic 3D models with thermal textures using the SfM pipeline and GAN. The proposed method uses visible range images as an input. The images are processed in two ways. Firstly, they are used for point matching and dense point cloud generation. Secondly, the images are fed into a GAN that performs the transformation from the visible range to the thermal range. We evaluate the proposed method using real infrared imagery captured with a FLIR ONE PRO camera. We generated a dataset with 2000 pairs of real images captured in thermal and visible range. The dataset is used to train the GAN network and to generate 3D models using SfM. The evaluation of the generated 3D models and infrared textures proved that they are similar to the ground truth model in both thermal emissivity and geometrical shape.

Gradient-based interpolation method for division-of-focal-plane polarimeters.

PubMed

Gao, Shengkui; Gruev, Viktor

2013-01-14

Recent advancements in nanotechnology and nanofabrication have allowed for the emergence of the division-of-focal-plane (DoFP) polarization imaging sensors. These sensors capture polarization properties of the optical field at every imaging frame. However, the DoFP polarization imaging sensors suffer from large registration error as well as reduced spatial-resolution output. These drawbacks can be improved by applying proper image interpolation methods for the reconstruction of the polarization results. In this paper, we present a new gradient-based interpolation method for DoFP polarimeters. The performance of the proposed interpolation method is evaluated against several previously published interpolation methods by using visual examples and root mean square error (RMSE) comparison. We found that the proposed gradient-based interpolation method can achieve better visual results while maintaining a lower RMSE than other interpolation methods under various dynamic ranges of a scene ranging from dim to bright conditions.

Spatial structures in UTLS trace gases imaged by the GLORIA instrument during the TACTS/ESMVal campaign in 2012

NASA Astrophysics Data System (ADS)

Guggenmoser, Tobias; Ungermann, Joern; Blank, Joerg; Kleinert, Anne; Grooss, Jens-Uwe; Vogel, Baerbel

2013-04-01

The combined TACTS/ESMVal measurement campaign was conducted during August and September 2012. Its objective was to improve our understanding of the UTLS region using a combination of airborne in situ and remote sensing devices. While the focus of TACTS was on exchange processes across the tropopause, ESMVal's objective was to obtain a wide latitude coverage from northern to southern polar regions. The campaign was based in Oberpfaffenhofen (D), with support bases in Sal (CV), Malé (MV), and Cape Town (ZA). A total of 13 scientific flights, ranging in latitude from 65°S to 80°N, were performed aboard the High Altitude and LOng Range (HALO) research aircraft, operated by the German Aerospace Agency (DLR). One of the core instruments was GLORIA, the Gimballed Limb Observer for Radiance Imaging of the Atmosphere. GLORIA is a joint development of Forschungszentrum Jülich and Karlsruher Institut für Technologie. It is an imaging Fourier transform spectrometer in the thermal infrared range, designed to optimize either spatial or spectral resolution, so as to yield data for dynamical as well as chemical analysis. In dynamics mode, the instrument also pans between measurements, making it possible to observe the same target volume from multiple directions. Combined with the right flight pattern, a 3D tomographic analysis becomes possible. In this presentation, we will show our first results for temperature and trace gas mixing ratios from a selection of the TACTS/ESMVal flights, concentrating on dynamics mode measurements in the polar regions. We will show the resolution of filaments in the UTLS region in two-dimensional cross-sections along the flight path, as well as preliminary results from true 3D retrievals.

Microwave soft x-ray microscopy for nanoscale magnetization dynamics in the 5–10 GHz frequency range

DOE PAGES

Bonetti, Stefano; Kukreja, Roopali; Chen, Zhao; ...

2015-09-10

In this study, we present a scanning transmission x-ray microscopy setup combined with a novel microwave synchronization scheme in order to study high frequency magnetization dynamics at synchrotron light sources. The sensitivity necessary to detect small changes of the magnetization on short time scales and nanometer spatial dimensions is achieved by combination of the developed excitation mechanism with a single photon counting electronics that is locked to the synchrotron operation frequency. The required mechanical stability is achieved by a compact design of the microscope. Our instrument is capable of creating direct images of dynamical phenomena in the 5-10 GHz range,more » with 35 nm resolution. When used together with circularly polarized x-rays, the above capabilities can be combined to study magnetic phenomena at microwave frequencies, such as ferromagnetic resonance (FMR) and spin waves. We demonstrate the capabilities of our technique by presenting phase resolved images of a –6 GHz nanoscale spin wave generated by a spin torque oscillator, as well as the uniform ferromagnetic precession with ~0.1° amplitude at –9 GHz in a micrometer-sized cobalt strip.« less

Time-Resolved Particle Image Velocimetry Measurements with Wall Shear Stress and Uncertainty Quantification for the FDA Nozzle Model.

PubMed

Raben, Jaime S; Hariharan, Prasanna; Robinson, Ronald; Malinauskas, Richard; Vlachos, Pavlos P

2016-03-01

We present advanced particle image velocimetry (PIV) processing, post-processing, and uncertainty estimation techniques to support the validation of computational fluid dynamics analyses of medical devices. This work is an extension of a previous FDA-sponsored multi-laboratory study, which used a medical device mimicking geometry referred to as the FDA benchmark nozzle model. Experimental measurements were performed using time-resolved PIV at five overlapping regions of the model for Reynolds numbers in the nozzle throat of 500, 2000, 5000, and 8000. Images included a twofold increase in spatial resolution in comparison to the previous study. Data was processed using ensemble correlation, dynamic range enhancement, and phase correlations to increase signal-to-noise ratios and measurement accuracy, and to resolve flow regions with large velocity ranges and gradients, which is typical of many blood-contacting medical devices. Parameters relevant to device safety, including shear stress at the wall and in bulk flow, were computed using radial basis functions. In addition, in-field spatially resolved pressure distributions, Reynolds stresses, and energy dissipation rates were computed from PIV measurements. Velocity measurement uncertainty was estimated directly from the PIV correlation plane, and uncertainty analysis for wall shear stress at each measurement location was performed using a Monte Carlo model. Local velocity uncertainty varied greatly and depended largely on local conditions such as particle seeding, velocity gradients, and particle displacements. Uncertainty in low velocity regions in the sudden expansion section of the nozzle was greatly reduced by over an order of magnitude when dynamic range enhancement was applied. Wall shear stress uncertainty was dominated by uncertainty contributions from velocity estimations, which were shown to account for 90-99% of the total uncertainty. This study provides advancements in the PIV processing methodologies over the previous work through increased PIV image resolution, use of robust image processing algorithms for near-wall velocity measurements and wall shear stress calculations, and uncertainty analyses for both velocity and wall shear stress measurements. The velocity and shear stress analysis, with spatially distributed uncertainty estimates, highlights the challenges of flow quantification in medical devices and provides potential methods to overcome such challenges.

Subelectron readout noise focal plane arrays for space imaging

NASA Astrophysics Data System (ADS)

Atlas, Gene; Wadsworth, Mark

2004-01-01

Readout noise levels of under 1 electron have long been a goal for the FPA community. In the quest to enhance the FPA sensitivity, various approaches have been attempted ranging from the exotic Photo-multiplier tubes, Image Intensifier tubes, Avalanche photo diodes, and now the on-chip avalanche charge amplification technologies from the CCD manufacturers. While these techniques reduce the readout noise, each offers a set of compromises that negatively affect the overall performance of the sensor in parameters such as power dissipation, dynamic range, uniformity or system complexity. In this work, we overview the benefits and tradeoffs of each approach, and introduce a new technique based on ImagerLabs" exclusive HIT technology which promises sub-electron read noise and other benefits without the tradeoffs of the other noise reduction techniques.

Ultrahigh resolution photographic films for X-ray/EUV/FUV astronomy

NASA Technical Reports Server (NTRS)

Hoover, Richard B.; Walker, Arthur B. C., Jr.; Deforest, Craig E.; Watts, Richard; Tarrio, Charles

1993-01-01

The quest for ultrahigh resolution full-disk images of the sun at soft X-ray/EUV/FUV wavelengths has increased the demand for photographic films with broad spectral sensitivity, high spatial resolution, and wide dynamic range. These requirements were made more stringent by the recent development of multilayer telescopes and coronagraphs capable of operating at normal incidence at soft X-ray/EUV wavelengths. Photographic films are the only detectors now available with the information storage capacity and dynamic range such as is required for recording images of the solar disk and corona simultaneously with sub arc second spatial resolution. During the Stanford/MSFC/LLNL Rocket X-Ray Spectroheliograph and Multi-Spectral Solar Telescope Array (MSSTA) programs, we utilized photographic films to obtain high resolution full-disk images of the sun at selected soft X-ray/EUV/FUV wavelengths. In order to calibrate our instrumentation for quantitative analysis of our solar data and to select the best emulsions and processing conditions for the MSSTA reflight, we recently tested several photographic films. These studies were carried out at the NIST SURF II synchrotron and the Stanford Synchrotron Radiation Laboratory. In this paper, we provide the results of those investigations.

A robust color signal processing with wide dynamic range WRGB CMOS image sensor

NASA Astrophysics Data System (ADS)

Kawada, Shun; Kuroda, Rihito; Sugawa, Shigetoshi

2011-01-01

We have developed a robust color reproduction methodology by a simple calculation with a new color matrix using the formerly developed wide dynamic range WRGB lateral overflow integration capacitor (LOFIC) CMOS image sensor. The image sensor was fabricated through a 0.18 μm CMOS technology and has a 45 degrees oblique pixel array, the 4.2 μm effective pixel pitch and the W pixels. A W pixel was formed by replacing one of the two G pixels in the Bayer RGB color filter. The W pixel has a high sensitivity through the visible light waveband. An emerald green and yellow (EGY) signal is generated from the difference between the W signal and the sum of RGB signals. This EGY signal mainly includes emerald green and yellow lights. These colors are difficult to be reproduced accurately by the conventional simple linear matrix because their wave lengths are in the valleys of the spectral sensitivity characteristics of the RGB pixels. A new linear matrix based on the EGY-RGB signal was developed. Using this simple matrix, a highly accurate color processing with a large margin to the sensitivity fluctuation and noise has been achieved.

Time-resolved imaging of flyer dynamics for femtosecond laser-induced backward transfer of solid polymer thin films

NASA Astrophysics Data System (ADS)

Feinaeugle, M.; Gregorčič, P.; Heath, D. J.; Mills, B.; Eason, R. W.

2017-02-01

We have studied the transfer regimes and dynamics of polymer flyers from laser-induced backward transfer (LIBT) via time-resolved shadowgraphy. Imaging of the flyer ejection phase of LIBT of 3.8 μm and 6.4 μm thick SU-8 polymer films on germanium and silicon carrier substrates was performed over a time delay range of 1.4-16.4 μs after arrival of the laser pulse. The experiments were carried out with 150 fs, 800 nm pulses spatially shaped using a digital micromirror device, and laser fluences of up to 3.5 J/cm2 while images were recorded via a CCD camera and a spark discharge lamp. Velocities of flyers found in the range of 6-20 m/s, and the intact and fragmented ejection regimes, were a function of donor thickness, carrier and laser fluence. The crater profile of the donor after transfer and the resulting flyer profile indicated different flyer ejection modes for Si carriers and high fluences. The results contribute to better understanding of the LIBT process, and help to determine experimental parameters for successful LIBT of intact deposits.

Enhanced visualization of abnormalities in digital-mammographic images

NASA Astrophysics Data System (ADS)

Young, Susan S.; Moore, William E.

2002-05-01

This paper describes two new presentation methods that are intended to improve the ability of radiologists to visualize abnormalities in mammograms by enhancing the appearance of the breast parenchyma pattern relative to the fatty-tissue surroundings. The first method, referred to as mountain- view, is obtained via multiscale edge decomposition through filter banks. The image is displayed in a multiscale edge domain that causes the image to have a topographic-like appearance. The second method displays the image in the intensity domain and is referred to as contrast-enhancement presentation. The input image is first passed through a decomposition filter bank to produce a filtered output (Id). The image at the lowest resolution is processed using a LUT (look-up table) to produce a tone scaled image (I'). The LUT is designed to optimally map the code value range corresponding to the parenchyma pattern in the mammographic image into the dynamic range of the output medium. The algorithm uses a contrast weight control mechanism to produce the desired weight factors to enhance the edge information corresponding to the parenchyma pattern. The output image is formed using a reconstruction filter bank through I' and enhanced Id.

Methods for reverberation suppression utilizing dual frequency band imaging.

PubMed

Rau, Jochen M; Måsøy, Svein-Erik; Hansen, Rune; Angelsen, Bjørn; Tangen, Thor Andreas

2013-09-01

Reverberations impair the contrast resolution of diagnostic ultrasound images. Tissue harmonic imaging is a common method to reduce these artifacts, but does not remove all reverberations. Dual frequency band imaging (DBI), utilizing a low frequency pulse which manipulates propagation of the high frequency imaging pulse, has been proposed earlier for reverberation suppression. This article adds two different methods for reverberation suppression with DBI: the delay corrected subtraction (DCS) and the first order content weighting (FOCW) method. Both methods utilize the propagation delay of the imaging pulse of two transmissions with alternating manipulation pressure to extract information about its depth of first scattering. FOCW further utilizes this information to estimate the content of first order scattering in the received signal. Initial evaluation is presented where both methods are applied to simulated and in vivo data. Both methods yield visual and measurable substantial improvement in image contrast. Comparing DCS with FOCW, DCS produces sharper images and retains more details while FOCW achieves best suppression levels and, thus, highest image contrast. The measured improvement in contrast ranges from 8 to 27 dB for DCS and from 4 dB up to the dynamic range for FOCW.

Single frequency thermal wave radar: A next-generation dynamic thermography for quantitative non-destructive imaging over wide modulation frequency ranges.

PubMed

Melnikov, Alexander; Chen, Liangjie; Ramirez Venegas, Diego; Sivagurunathan, Koneswaran; Sun, Qiming; Mandelis, Andreas; Rodriguez, Ignacio Rojas

2018-04-01

Single-Frequency Thermal Wave Radar Imaging (SF-TWRI) was introduced and used to obtain quantitative thickness images of coatings on an aluminum block and on polyetherketone, and to image blind subsurface holes in a steel block. In SF-TWR, the starting and ending frequencies of a linear frequency modulation sweep are chosen to coincide. Using the highest available camera frame rate, SF-TWRI leads to a higher number of sampled points along the modulation waveform than conventional lock-in thermography imaging because it is not limited by conventional undersampling at high frequencies due to camera frame-rate limitations. This property leads to large reduction in measurement time, better quality of images, and higher signal-noise-ratio across wide frequency ranges. For quantitative thin-coating imaging applications, a two-layer photothermal model with lumped parameters was used to reconstruct the layer thickness from multi-frequency SF-TWR images. SF-TWRI represents a next-generation thermography method with superior features for imaging important classes of thin layers, materials, and components that require high-frequency thermal-wave probing well above today's available infrared camera technology frame rates.

Single frequency thermal wave radar: A next-generation dynamic thermography for quantitative non-destructive imaging over wide modulation frequency ranges

NASA Astrophysics Data System (ADS)

Melnikov, Alexander; Chen, Liangjie; Ramirez Venegas, Diego; Sivagurunathan, Koneswaran; Sun, Qiming; Mandelis, Andreas; Rodriguez, Ignacio Rojas

2018-04-01

Single-Frequency Thermal Wave Radar Imaging (SF-TWRI) was introduced and used to obtain quantitative thickness images of coatings on an aluminum block and on polyetherketone, and to image blind subsurface holes in a steel block. In SF-TWR, the starting and ending frequencies of a linear frequency modulation sweep are chosen to coincide. Using the highest available camera frame rate, SF-TWRI leads to a higher number of sampled points along the modulation waveform than conventional lock-in thermography imaging because it is not limited by conventional undersampling at high frequencies due to camera frame-rate limitations. This property leads to large reduction in measurement time, better quality of images, and higher signal-noise-ratio across wide frequency ranges. For quantitative thin-coating imaging applications, a two-layer photothermal model with lumped parameters was used to reconstruct the layer thickness from multi-frequency SF-TWR images. SF-TWRI represents a next-generation thermography method with superior features for imaging important classes of thin layers, materials, and components that require high-frequency thermal-wave probing well above today's available infrared camera technology frame rates.

Fast two-layer two-photon imaging of neuronal cell populations using an electrically tunable lens

PubMed Central

Grewe, Benjamin F.; Voigt, Fabian F.; van ’t Hoff, Marcel; Helmchen, Fritjof

2011-01-01

Functional two-photon Ca2+-imaging is a versatile tool to study the dynamics of neuronal populations in brain slices and living animals. However, population imaging is typically restricted to a single two-dimensional image plane. By introducing an electrically tunable lens into the excitation path of a two-photon microscope we were able to realize fast axial focus shifts within 15 ms. The maximum axial scan range was 0.7 mm employing a 40x NA0.8 water immersion objective, plenty for typically required ranges of 0.2–0.3 mm. By combining the axial scanning method with 2D acousto-optic frame scanning and random-access scanning, we measured neuronal population activity of about 40 neurons across two imaging planes separated by 40 μm and achieved scan rates up to 20–30 Hz. The method presented is easily applicable and allows upgrading of existing two-photon microscopes for fast 3D scanning. PMID:21750778

Digital holographic microscopy applied to measurement of a flow in a T-shaped micromixer

NASA Astrophysics Data System (ADS)

Ooms, T. A.; Lindken, R.; Westerweel, J.

2009-12-01

In this paper, we describe measurements of a three-dimensional (3D) flow in a T-shaped micromixer by means of digital holographic microscopy. Imaging tracer particles in a microscopic flow with conventional microscopy is accompanied by a small depth-of-field, which hinders true volumetric flow measurements. In holographic microscopy, the depth of the measurement domain does not have this limitation because any desired image plane can be reconstructed after recording. Our digital holographic microscope (DHM) consists of a conventional in-line recording system with an added magnifying optical element. The measured flow velocity and the calculated vorticity illustrate four streamwise vortices in the micromixer outflow channel. Because the investigated flow is stationary and strongly 3D, the DHM performance (i.e. accuracy and resolution) can be precisely investigated. The obtained Dynamic spatial range and Dynamic velocity range are larger than 20 and 30, respectively. High-speed multiple-frame measurements illustrate the capability to simultaneously track about 80 particles in a volumetric measurement domain.

Creating cinematic wide gamut HDR-video for the evaluation of tone mapping operators and HDR-displays

NASA Astrophysics Data System (ADS)

Froehlich, Jan; Grandinetti, Stefan; Eberhardt, Bernd; Walter, Simon; Schilling, Andreas; Brendel, Harald

2014-03-01

High quality video sequences are required for the evaluation of tone mapping operators and high dynamic range (HDR) displays. We provide scenic and documentary scenes with a dynamic range of up to 18 stops. The scenes are staged using professional film lighting, make-up and set design to enable the evaluation of image and material appearance. To address challenges for HDR-displays and temporal tone mapping operators, the sequences include highlights entering and leaving the image, brightness changing over time, high contrast skin tones, specular highlights and bright, saturated colors. HDR-capture is carried out using two cameras mounted on a mirror-rig. To achieve a cinematic depth of field, digital motion picture cameras with Super-35mm size sensors are used. We provide HDR-video sequences to serve as a common ground for the evaluation of temporal tone mapping operators and HDR-displays. They are available to the scientific community for further research.

Optical and x-ray characterization of two novel CMOS image sensors

NASA Astrophysics Data System (ADS)

Bohndiek, Sarah E.; Arvanitis, Costas D.; Venanzi, Cristian; Royle, Gary J.; Clark, Andy T.; Crooks, Jamie P.; Prydderch, Mark L.; Turchetta, Renato; Blue, Andrew; Speller, Robert D.

2007-02-01

A UK consortium (MI3) has been founded to develop advanced CMOS pixel designs for scientific applications. Vanilla, a 520x520 array of 25μm pixels benefits from flushed reset circuitry for low noise and random pixel access for region of interest (ROI) readout. OPIC, a 64x72 test structure array of 30μm digital pixels has thresholding capabilities for sparse readout at 3,700fps. Characterization is performed with both optical illumination and x-ray exposure via a scintillator. Vanilla exhibits 34+/-3e - read noise, interactive quantum efficiency of 54% at 500nm and can read a 6x6 ROI at 24,395fps. OPIC has 46+/-3e - read noise and a wide dynamic range of 65dB due to high full well capacity. Based on these characterization studies, Vanilla could be utilized in applications where demands include high spectral response and high speed region of interest readout while OPIC could be used for high speed, high dynamic range imaging.

Mapping the spatial and temporal dynamics of the velvet mesquite with MODIS and AVIRIS: Case study at the Santa Rita Experimental Range

NASA Astrophysics Data System (ADS)

Kaurivi, Jorry Zebby Ujama

The general objective of this research is to develop a methodology that will allow mapping and quantifying shrub encroachment with remote sensing. The multitemporal properties of the Moderate Resolution Imaging Spectroradiometer (MODIS) -250m, 16-day vegetation index products were combined with the hyperspectral and high spatial resolution (3.6m) computation of the Airborne Visible-Infrared Imaging Spectrometer (AVIRIS) to detect the dynamics of mesquite and grass/soil matrix at two sites of high (19.5%) and low (5.7%) mesquite cover in the Santa Rita Experimental Range (SRER). MODIS results showed separability between grassland and mesquite based on phenology. Mesquite landscapes had longer green peak starting in April through February, while the grassland only peaked during the monsoon season (July through October). AVIRIS revealed spectral separability, but high variation in the data implicated high heterogeneity in the landscape. Nonetheless, the methodology for larger data was developed in this study and combines ground, air and satellite data.

Imaging shock waves in diamond with both high temporal and spatial resolution at an XFEL

DOE PAGES

Schropp, Andreas; Hoppe, Robert; Meier, Vivienne; ...

2015-06-18

The advent of hard x-ray free-electron lasers (XFELs) has opened up a variety of scientific opportunities in areas as diverse as atomic physics, plasma physics, nonlinear optics in the x-ray range, and protein crystallography. In this article, we access a new field of science by measuring quantitatively the local bulk properties and dynamics of matter under extreme conditions, in this case by using the short XFEL pulse to image an elastic compression wave in diamond. The elastic wave was initiated by an intense optical laser pulse and was imaged at different delay times after the optical pump pulse using magnifiedmore » x-ray phase-contrast imaging. The temporal evolution of the shock wave can be monitored, yielding detailed information on shock dynamics, such as the shock velocity, the shock front width, and the local compression of the material. The method provides a quantitative perspective on the state of matter in extreme conditions.« less

Imaging Shock Waves in Diamond with Both High Temporal and Spatial Resolution at an XFEL.

PubMed

Schropp, Andreas; Hoppe, Robert; Meier, Vivienne; Patommel, Jens; Seiboth, Frank; Ping, Yuan; Hicks, Damien G; Beckwith, Martha A; Collins, Gilbert W; Higginbotham, Andrew; Wark, Justin S; Lee, Hae Ja; Nagler, Bob; Galtier, Eric C; Arnold, Brice; Zastrau, Ulf; Hastings, Jerome B; Schroer, Christian G

2015-06-18

The advent of hard x-ray free-electron lasers (XFELs) has opened up a variety of scientific opportunities in areas as diverse as atomic physics, plasma physics, nonlinear optics in the x-ray range, and protein crystallography. In this article, we access a new field of science by measuring quantitatively the local bulk properties and dynamics of matter under extreme conditions, in this case by using the short XFEL pulse to image an elastic compression wave in diamond. The elastic wave was initiated by an intense optical laser pulse and was imaged at different delay times after the optical pump pulse using magnified x-ray phase-contrast imaging. The temporal evolution of the shock wave can be monitored, yielding detailed information on shock dynamics, such as the shock velocity, the shock front width, and the local compression of the material. The method provides a quantitative perspective on the state of matter in extreme conditions.

In-Vivo Real-Time X-ray μ-Imaging

NASA Astrophysics Data System (ADS)

Dammer, Jiri; Holy, Tomas; Jakubek, Jan; Jakubek, Martin; Pospisil, Stanislav; Vavrík, Daniel

2007-11-01

The technique of X-ray transmission imaging is available for more than 100 years and it is still one of the fastest and easiest ways how to study the internal structure of living biological samples. The advances in semiconductor technology in last years make possible to fabricate new types of X-ray detectors with direct conversion of interacting X-ray photon to an electric signal. Especially semiconductor pixel detectors seem to be very promising. Compared to the film technique they bring single-quantum and real-time digital information about the studied object with high resolution, high sensitivity and broad dynamic range. These pixel detector-based imaging stand promising as a new tool in the field of small animal imaging, for cancer research and for observation of dynamic processes inside organisms. These detectors open up for instance new possibilities for researchers to perform non-invasive studies of tissue for mutations or pathologies and to monitor disease progression or response to therapy.

Characterization of photocathode dark current vs. temperature in image intensifier tube modules and intensified televisions

NASA Astrophysics Data System (ADS)

Bender, Edward J.; Wood, Michael V.; Hart, Steve; Heim, Gerald B.; Torgerson, John A.

2004-10-01

Image intensifiers (I2) have gained wide acceptance throughout the Army as the premier nighttime mobility sensor for the individual soldier, with over 200,000 fielded systems. There is increasing need, however, for such a sensor with a video output, so that it can be utilized in remote vehicle platforms, and/or can be electronically fused with other sensors. The image-intensified television (I2TV), typically consisting of an image intensifier tube coupled via fiber optic to a solid-state imaging array, has been the primary solution to this need. I2TV platforms in vehicles, however, can generate high internal heat loads and must operate in high-temperature environments. Intensifier tube dark current, called "Equivalent Background Input" or "EBI", is not a significant factor at room temperature, but can seriously degrade image contrast and intra-scene dynamic range at such high temperatures. Cooling of the intensifier's photocathode is the only practical solution to this problem. The US Army RDECOM CERDEC Night Vision & Electronic Sensors Directorate (NVESD) and Ball Aerospace have collaborated in the reported effort to more rigorously characterize intensifier EBI versus temperature. NVESD performed non-imaging EBI measurements of Generation 2 and 3 tube modules over a large range of ambient temperature, while Ball performed an imaging evaluation of Generation 3 I2TVs over a similar temperature range. The findings and conclusions of this effort are presented.

Illumination normalization of face image based on illuminant direction estimation and improved Retinex.

PubMed

Yi, Jizheng; Mao, Xia; Chen, Lijiang; Xue, Yuli; Rovetta, Alberto; Caleanu, Catalin-Daniel

2015-01-01

Illumination normalization of face image for face recognition and facial expression recognition is one of the most frequent and difficult problems in image processing. In order to obtain a face image with normal illumination, our method firstly divides the input face image into sixteen local regions and calculates the edge level percentage in each of them. Secondly, three local regions, which meet the requirements of lower complexity and larger average gray value, are selected to calculate the final illuminant direction according to the error function between the measured intensity and the calculated intensity, and the constraint function for an infinite light source model. After knowing the final illuminant direction of the input face image, the Retinex algorithm is improved from two aspects: (1) we optimize the surround function; (2) we intercept the values in both ends of histogram of face image, determine the range of gray levels, and stretch the range of gray levels into the dynamic range of display device. Finally, we achieve illumination normalization and get the final face image. Unlike previous illumination normalization approaches, the method proposed in this paper does not require any training step or any knowledge of 3D face and reflective surface model. The experimental results using extended Yale face database B and CMU-PIE show that our method achieves better normalization effect comparing with the existing techniques.

Subjective matters: from image quality to image psychology

NASA Astrophysics Data System (ADS)

Fedorovskaya, Elena A.; De Ridder, Huib

2013-03-01

From the advent of digital imaging through several decades of studies, the human vision research community systematically focused on perceived image quality and digital artifacts due to resolution, compression, gamma, dynamic range, capture and reproduction noise, blur, etc., to help overcome existing technological challenges and shortcomings. Technological advances made digital images and digital multimedia nearly flawless in quality, and ubiquitous and pervasive in usage, provide us with the exciting but at the same time demanding possibility to turn to the domain of human experience including higher psychological functions, such as cognition, emotion, awareness, social interaction, consciousness and Self. In this paper we will outline the evolution of human centered multidisciplinary studies related to imaging and propose steps and potential foci of future research.

Modelling and restoration of ultrasonic phased-array B-scan images.

PubMed

Ardouin, J P; Venetsanopoulos, A N

1985-10-01

A model is presented for the radio-frequency image produced by a B-scan (pulse-echo) ultrasound imaging system using a phased-array transducer. This type of scanner is widely used for real-time heart imaging. The model allows for dynamic focusing as well as an acoustic lens focusing the beam in the elevation plane. A result of the model is an expression to compute the space-variant point spread function (PSF) of the system. This is made possible by the use of a combination of Fresnel and Fraunhoffer approximations which are valid in the range of interest for practical applications. The PSF is used to design restoration filters in order to improve image resolution. The filters are then applied to experimental images of wires.

Comparative study of image contrast in scanning electron microscope and helium ion microscope.

PubMed

O'Connell, R; Chen, Y; Zhang, H; Zhou, Y; Fox, D; Maguire, P; Wang, J J; Rodenburg, C

2017-12-01

Images of Ga + -implanted amorphous silicon layers in a 110 n-type silicon substrate have been collected by a range of detectors in a scanning electron microscope and a helium ion microscope. The effects of the implantation dose and imaging parameters (beam energy, dwell time, etc.) on the image contrast were investigated. We demonstrate a similar relationship for both the helium ion microscope Everhart-Thornley and scanning electron microscope Inlens detectors between the contrast of the images and the Ga + density and imaging parameters. These results also show that dynamic charging effects have a significant impact on the quantification of the helium ion microscope and scanning electron microscope contrast. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

A study of image quality for radar image processing. [synthetic aperture radar imagery

NASA Technical Reports Server (NTRS)

King, R. W.; Kaupp, V. H.; Waite, W. P.; Macdonald, H. C.

1982-01-01

Methods developed for image quality metrics are reviewed with focus on basic interpretation or recognition elements including: tone or color; shape; pattern; size; shadow; texture; site; association or context; and resolution. Seven metrics are believed to show promise as a way of characterizing the quality of an image: (1) the dynamic range of intensities in the displayed image; (2) the system signal-to-noise ratio; (3) the system spatial bandwidth or bandpass; (4) the system resolution or acutance; (5) the normalized-mean-square-error as a measure of geometric fidelity; (6) the perceptual mean square error; and (7) the radar threshold quality factor. Selective levels of degradation are being applied to simulated synthetic radar images to test the validity of these metrics.

Characterization of ultrafast laser-ablation plasma plumes at various Ar ambient pressures

DOE PAGES

Diwakar, P. K.; Harilal, S. S.; Phillips, M. C.; ...

2015-07-30

Expansion dynamics and internal plume structures of fs laser ablated brass plasma in Ar at various pressure levels ranging from vacuum to atmospheric were studied using multitude of diagnostic tools including time resolved and time integrated 2-dimensional imaging, optical time of flight measurements and visible emission spectroscopy. Temporal evolution of excited Cu and Zn species in the plume were imaged using band pass interference filters and compared its hydrodynamic expansion features with spectrally integrated images of the plume. 2D imaging coupled with monochromatic line selection showed several interesting features at various pressure levels which include velocity differences among the plumemore » species, emission intensity distribution, plasma temperature, electron density etc. Plume confinement, enhanced signal intensity, and dual peak structures in time-of-flight profiles were observed at intermediate pressure range of ~10 Torr. Optimum signal to background ratio was also observed in this pressure range. As a result, possible mechanisms for observed changes in plume shape, optical emission intensity and dual peak structures in time-of-flight profiles were discussed.« less

Dynamical Modeling of NGC 6397: Simulated HST Imaging

NASA Astrophysics Data System (ADS)

Dull, J. D.; Cohn, H. N.; Lugger, P. M.; Slavin, S. D.; Murphy, B. W.

1994-12-01

The proximity of NGC 6397 (2.2 kpc) provides an ideal opportunity to test current dynamical models for globular clusters with the HST Wide-Field/Planetary Camera (WFPC2)\\@. We have used a Monte Carlo algorithm to generate ensembles of simulated Planetary Camera (PC) U-band images of NGC 6397 from evolving, multi-mass Fokker-Planck models. These images, which are based on the post-repair HST-PC point-spread function, are used to develop and test analysis methods for recovering structural information from actual HST imaging. We have considered a range of exposure times up to 2.4times 10(4) s, based on our proposed HST Cycle 5 observations. Our Fokker-Planck models include energy input from dynamically-formed binaries. We have adopted a 20-group mass spectrum extending from 0.16 to 1.4 M_sun. We use theoretical luminosity functions for red giants and main sequence stars. Horizontal branch stars, blue stragglers, white dwarfs, and cataclysmic variables are also included. Simulated images are generated for cluster models at both maximal core collapse and at a post-collapse bounce. We are carrying out stellar photometry on these images using ``DAOPHOT-assisted aperture photometry'' software that we have developed. We are testing several techniques for analyzing the resulting star counts, to determine the underlying cluster structure, including parametric model fits and the nonparametric density estimation methods. Our simulated images also allow us to investigate the accuracy and completeness of methods for carrying out stellar photometry in HST Planetary Camera images of dense cluster cores.

Onboard TDI stage estimation and calibration using SNR analysis

NASA Astrophysics Data System (ADS)

Haghshenas, Javad

2017-09-01

Electro-Optical design of a push-broom space camera for a Low Earth Orbit (LEO) remote sensing satellite is performed based on the noise analysis of TDI sensors for very high GSDs and low light level missions. It is well demonstrated that the CCD TDI mode of operation provides increased photosensitivity relative to a linear CCD array, without the sacrifice of spatial resolution. However, for satellite imaging, in order to utilize the advantages which the TDI mode of operation offers, attention should be given to the parameters which affect the image quality of TDI sensors such as jitters, vibrations, noises and etc. A predefined TDI stages may not properly satisfy image quality requirement of the satellite camera. Furthermore, in order to use the whole dynamic range of the sensor, imager must be capable to set the TDI stages in every shots based on the affecting parameters. This paper deals with the optimal estimation and setting the stages based on tradeoffs among MTF, noises and SNR. On-board SNR estimation is simulated using the atmosphere analysis based on the MODTRAN algorithm in PcModWin software. According to the noises models, we have proposed a formulation to estimate TDI stages in such a way to satisfy the system SNR requirement. On the other hand, MTF requirement must be satisfy in the same manner. A proper combination of both parameters will guaranty the full dynamic range usage along with the high SNR and image quality.

The focusing optics x-ray solar imager (FOXSI): instrument and first flight

NASA Astrophysics Data System (ADS)

Krucker, Säm.; Christe, Steven; Glesener, Lindsay; Ishikawa, Shinnosuke; Ramsey, Brian; Gubarev, Mikhail; Saito, Shinya; Takahashi, Tadayuki; Watanabe, Shin; Tajima, Hiroyasu; Tanaka, Takaaki; Turin, Paul; Glaser, David; Fermin, Jose; Lin, Robert P.

2013-09-01

Solar flares accelerate particles up to high energies (MeV and GeV scales for electrons and ions, respectively) through efficient acceleration processes that are not currently understood. Hard X-rays (HXRs) are the most direct diagnostic of flare-accelerated electrons. However, past and current solar HXR observers lack the necessary sensitivity and imaging dynamic range to make detailed studies of faint HXR sources in the solar corona (where particle acceleration is thought to occur); these limitations are mainly due to the indirect Fourier imaging techniques used by these observers. With greater sensitivity and dynamic range, electron acceleration sites could be systematically studied in detail. Both these capabilities can be advanced by the use of direct focusing optics. The recently own Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload demonstrates the unique diagnostic power of focusing optics for observations of solar HXRs. FOXSI features grazing-incidence replicated nickel optics with 5 arcsecond resolution and fine-pitch silicon strip detectors with a 7.7 arcsecond strip pitch. FOXSI flew successfully on 2012 November 2, producing images and spectra of a microflare and performing a search for non-thermal emission (4{15 keV) from nanoflares occurring outside active regions in the quiet Sun. A future spacecraft version of FOXSI, featuring similar optics and detectors, could make detailed observations of HXRs from flare-accelerated electrons, identifying and characterizing particle acceleration sites and mapping out paths of energetic electrons as they leave these sites and propagate throughout the solar corona. This paper will describe the FOXSI instrument and present images from the first flight.

Do High Dynamic Range threatments improve the results of Structure from Motion approaches in Geomorphology?

NASA Astrophysics Data System (ADS)

Gómez-Gutiérrez, Álvaro; Juan de Sanjosé-Blasco, José; Schnabel, Susanne; de Matías-Bejarano, Javier; Pulido-Fernández, Manuel; Berenguer-Sempere, Fernando

2015-04-01

In this work, the hypothesis of improving 3D models obtained with Structure from Motion (SfM) approaches using images pre-processed by High Dynamic Range (HDR) techniques is tested. Photographs of the Veleta Rock Glacier in Spain were captured with different exposure values (EV0, EV+1 and EV-1), two focal lengths (35 and 100 mm) and under different weather conditions for the years 2008, 2009, 2011, 2012 and 2014. HDR images were produced using the different EV steps within Fusion F.1 software. Point clouds were generated using commercial and free available SfM software: Agisoft Photoscan and 123D Catch. Models Obtained using pre-processed images and non-preprocessed images were compared in a 3D environment with a benchmark 3D model obtained by means of a Terrestrial Laser Scanner (TLS). A total of 40 point clouds were produced, georeferenced and compared. Results indicated that for Agisoft Photoscan software differences in the accuracy between models obtained with pre-processed and non-preprocessed images were not significant from a statistical viewpoint. However, in the case of the free available software 123D Catch, models obtained using images pre-processed by HDR techniques presented a higher point density and were more accurate. This tendency was observed along the 5 studied years and under different capture conditions. More work should be done in the near future to corroborate whether the results of similar software packages can be improved by HDR techniques (e.g. ARC3D, Bundler and PMVS2, CMP SfM, Photosynth and VisualSFM).

A real-time monitoring system for night glare protection

NASA Astrophysics Data System (ADS)

Ma, Jun; Ni, Xuxiang

2010-11-01

When capturing a dark scene with a high bright object, the monitoring camera will be saturated in some regions and the details will be lost in and near these saturated regions because of the glare vision. This work aims at developing a real-time night monitoring system. The system can decrease the influence of the glare vision and gain more details from the ordinary camera when exposing a high-contrast scene like a car with its headlight on during night. The system is made up of spatial light modulator (The liquid crystal on silicon: LCoS), image sensor (CCD), imaging lens and DSP. LCoS, a reflective liquid crystal, can modular the intensity of reflective light at every pixel as a digital device. Through modulation function of LCoS, CCD is exposed with sub-region. With the control of DSP, the light intensity is decreased to minimum in the glare regions, and the light intensity is negative feedback modulated based on PID theory in other regions. So that more details of the object will be imaging on CCD and the glare protection of monitoring system is achieved. In experiments, the feedback is controlled by the embedded system based on TI DM642. Experiments shows: this feedback modulation method not only reduces the glare vision to improve image quality, but also enhances the dynamic range of image. The high-quality and high dynamic range image is real-time captured at 30hz. The modulation depth of LCoS determines how strong the glare can be removed.

Imaging Adenosine Triphosphate (ATP)

PubMed Central

Rajendran, Megha; Dane, Eric; Conley, Jason; Tantama, Mathew

2016-01-01

Adenosine triphosphate (ATP) is a universal mediator of metabolism and signaling across unicellular and multicellular species. There is a fundamental interdependence between the dynamics of ATP and the physiology that occurs inside and outside the cell. Characterizing and understanding ATP dynamics provides valuable mechanistic insight into processes that range from neurotransmission to the chemotaxis of immune cells. Therefore, we require the methodology to interrogate both temporal and spatial components of ATP dynamics from the subcellular to organismal levels in live specimens. Over the last several decades, a number of molecular probes that are specific for ATP have been developed. These probes have been combined with imaging approaches, particularly optical microscopy, to enable qualitative and quantitative detection of this critical molecule. In this review, we survey current examples of technologies that are available to visualize ATP in living cells and identify areas where new tools and approaches are needed to expand our capabilities. PMID:27638696

Imaging Adenosine Triphosphate (ATP).

PubMed

Rajendran, Megha; Dane, Eric; Conley, Jason; Tantama, Mathew

2016-08-01

Adenosine triphosphate (ATP) is a universal mediator of metabolism and signaling across unicellular and multicellular species. There is a fundamental interdependence between the dynamics of ATP and the physiology that occurs inside and outside the cell. Characterizing and understanding ATP dynamics provide valuable mechanistic insight into processes that range from neurotransmission to the chemotaxis of immune cells. Therefore, we require the methodology to interrogate both temporal and spatial components of ATP dynamics from the subcellular to the organismal levels in live specimens. Over the last several decades, a number of molecular probes that are specific to ATP have been developed. These probes have been combined with imaging approaches, particularly optical microscopy, to enable qualitative and quantitative detection of this critical molecule. In this review, we survey current examples of technologies available for visualizing ATP in living cells, and identify areas where new tools and approaches are needed to expand our capabilities. © 2016 Marine Biological Laboratory.

Multi-atlas attenuation correction supports full quantification of static and dynamic brain PET data in PET-MR

NASA Astrophysics Data System (ADS)

Mérida, Inés; Reilhac, Anthonin; Redouté, Jérôme; Heckemann, Rolf A.; Costes, Nicolas; Hammers, Alexander

2017-04-01

In simultaneous PET-MR, attenuation maps are not directly available. Essential for absolute radioactivity quantification, they need to be derived from MR or PET data to correct for gamma photon attenuation by the imaged object. We evaluate a multi-atlas attenuation correction method for brain imaging (MaxProb) on static [18F]FDG PET and, for the first time, on dynamic PET, using the serotoninergic tracer [18F]MPPF. A database of 40 MR/CT image pairs (atlases) was used. The MaxProb method synthesises subject-specific pseudo-CTs by registering each atlas to the target subject space. Atlas CT intensities are then fused via label propagation and majority voting. Here, we compared these pseudo-CTs with the real CTs in a leave-one-out design, contrasting the MaxProb approach with a simplified single-atlas method (SingleAtlas). We evaluated the impact of pseudo-CT accuracy on reconstructed PET images, compared to PET data reconstructed with real CT, at the regional and voxel levels for the following: radioactivity images; time-activity curves; and kinetic parameters (non-displaceable binding potential, BPND). On static [18F]FDG, the mean bias for MaxProb ranged between 0 and 1% for 73 out of 84 regions assessed, and exceptionally peaked at 2.5% for only one region. Statistical parametric map analysis of MaxProb-corrected PET data showed significant differences in less than 0.02% of the brain volume, whereas SingleAtlas-corrected data showed significant differences in 20% of the brain volume. On dynamic [18F]MPPF, most regional errors on BPND ranged from -1 to  +3% (maximum bias 5%) for the MaxProb method. With SingleAtlas, errors were larger and had higher variability in most regions. PET quantification bias increased over the duration of the dynamic scan for SingleAtlas, but not for MaxProb. We show that this effect is due to the interaction of the spatial tracer-distribution heterogeneity variation over time with the degree of accuracy of the attenuation maps. This work demonstrates that inaccuracies in attenuation maps can induce bias in dynamic brain PET studies. Multi-atlas attenuation correction with MaxProb enables quantification on hybrid PET-MR scanners, eschewing the need for CT.

Multi-atlas attenuation correction supports full quantification of static and dynamic brain PET data in PET-MR.

PubMed

Mérida, Inés; Reilhac, Anthonin; Redouté, Jérôme; Heckemann, Rolf A; Costes, Nicolas; Hammers, Alexander

2017-04-07

In simultaneous PET-MR, attenuation maps are not directly available. Essential for absolute radioactivity quantification, they need to be derived from MR or PET data to correct for gamma photon attenuation by the imaged object. We evaluate a multi-atlas attenuation correction method for brain imaging (MaxProb) on static [ 18 F]FDG PET and, for the first time, on dynamic PET, using the serotoninergic tracer [ 18 F]MPPF. A database of 40 MR/CT image pairs (atlases) was used. The MaxProb method synthesises subject-specific pseudo-CTs by registering each atlas to the target subject space. Atlas CT intensities are then fused via label propagation and majority voting. Here, we compared these pseudo-CTs with the real CTs in a leave-one-out design, contrasting the MaxProb approach with a simplified single-atlas method (SingleAtlas). We evaluated the impact of pseudo-CT accuracy on reconstructed PET images, compared to PET data reconstructed with real CT, at the regional and voxel levels for the following: radioactivity images; time-activity curves; and kinetic parameters (non-displaceable binding potential, BP ND ). On static [ 18 F]FDG, the mean bias for MaxProb ranged between 0 and 1% for 73 out of 84 regions assessed, and exceptionally peaked at 2.5% for only one region. Statistical parametric map analysis of MaxProb-corrected PET data showed significant differences in less than 0.02% of the brain volume, whereas SingleAtlas-corrected data showed significant differences in 20% of the brain volume. On dynamic [ 18 F]MPPF, most regional errors on BP ND ranged from -1 to  +3% (maximum bias 5%) for the MaxProb method. With SingleAtlas, errors were larger and had higher variability in most regions. PET quantification bias increased over the duration of the dynamic scan for SingleAtlas, but not for MaxProb. We show that this effect is due to the interaction of the spatial tracer-distribution heterogeneity variation over time with the degree of accuracy of the attenuation maps. This work demonstrates that inaccuracies in attenuation maps can induce bias in dynamic brain PET studies. Multi-atlas attenuation correction with MaxProb enables quantification on hybrid PET-MR scanners, eschewing the need for CT.

Imaging electric field dynamics with graphene optoelectronics.

PubMed

Horng, Jason; Balch, Halleh B; McGuire, Allister F; Tsai, Hsin-Zon; Forrester, Patrick R; Crommie, Michael F; Cui, Bianxiao; Wang, Feng

2016-12-16

The use of electric fields for signalling and control in liquids is widespread, spanning bioelectric activity in cells to electrical manipulation of microstructures in lab-on-a-chip devices. However, an appropriate tool to resolve the spatio-temporal distribution of electric fields over a large dynamic range has yet to be developed. Here we present a label-free method to image local electric fields in real time and under ambient conditions. Our technique combines the unique gate-variable optical transitions of graphene with a critically coupled planar waveguide platform that enables highly sensitive detection of local electric fields with a voltage sensitivity of a few microvolts, a spatial resolution of tens of micrometres and a frequency response over tens of kilohertz. Our imaging platform enables parallel detection of electric fields over a large field of view and can be tailored to broad applications spanning lab-on-a-chip device engineering to analysis of bioelectric phenomena.

High-speed adaptive optics for imaging of the living human eye

PubMed Central

Yu, Yongxin; Zhang, Tianjiao; Meadway, Alexander; Wang, Xiaolin; Zhang, Yuhua

2015-01-01

The discovery of high frequency temporal fluctuation of human ocular wave aberration dictates the necessity of high speed adaptive optics (AO) correction for high resolution retinal imaging. We present a high speed AO system for an experimental adaptive optics scanning laser ophthalmoscope (AOSLO). We developed a custom high speed Shack-Hartmann wavefront sensor and maximized the wavefront detection speed based upon a trade-off among the wavefront spatial sampling density, the dynamic range, and the measurement sensitivity. We examined the temporal dynamic property of the ocular wavefront under the AOSLO imaging condition and improved the dual-thread AO control strategy. The high speed AO can be operated with a closed-loop frequency up to 110 Hz. Experiment results demonstrated that the high speed AO system can provide improved compensation for the wave aberration up to 30 Hz in the living human eye. PMID:26368408

Geocoronal imaging with Dynamics Explorer - A first look

NASA Technical Reports Server (NTRS)

Rairden, R. L.; Frank, L. A.; Craven, J. D.

1983-01-01

The ultraviolet photometer of the University of Iowa spin-scan auroral imaging instrumentation on board Dynamics Explorer-1 has returned numerous hydrogen Lyman alpha images of the geocorona from altitudes of 570 km to 23,300 km (1.09 R sub E to 4.66 R sub E geocentric radial distance). The hydrogen density gradient is shown by a plot of the zenith intensities throughout this range, which decrease to near celestial background values as the spacecraft approaches apogee. Characterizing the upper geocorona as optically thin (single-scattering), the zenith intensity is converted directly to vertical column density. This approximation loses its validity deeper in the geocorona, where the hydrogen is demonstrated to be optically thick in that there is no Lyman alpha limb brightening. Further study of the geocoronal hydrogen distribution will require computer modeling of the radiative transfer. Previously announced in STAR as N83-20889

Unique Capabilities of the SUVI Telescopes For Both Space Weather Prediction and Fundamental Solar Physics

NASA Astrophysics Data System (ADS)

Slater, G. L.; Seaton, D. B.

2017-12-01

The recently launched Solar UltraViolet Imager (SUVI) aboard NOAA's GOES-16 satellite, provides image data that can potentially both improve earth effective solar storm predictions and contribute to fundamental research on structure and dynamics in what may be called the 'high EUV corona'. The wide field of view ( 53 x 53 arcmin) and passband set covering UV and EUV emission from plasmas ranging in temperature from 5000 K to 7 million K, allow for the detailed observation of structure and dynamics in the high EUV corona. Imaging this region is increasingly recognized as being critical to understanding how the low corona connects, disconnects from, and reconnects to, the high corona and heliosphere during transient events in the low corona. We will illustrate this claim with observations taken from the first few months on operation of the SUVI instrument.

Research on Land Use Changes in Panjin City Basing on Remote Sensing Data

NASA Astrophysics Data System (ADS)

Ding, Hua; Li, Ru Ren; Shuang Sun, Li; Wang, Xin; Liu, Yu Mei

2018-05-01

Taking Landsat remote sensing image as the main data source, the research on land use changes in Panjin City in 2005 to 2015 is made with the support of remote sensing platform and GIS platform in this paper; the range of land use changes and change rate are analyzed through the classification of remote sensing image; the dynamic analysis on land changes is made with the help of transfer matrix of land use type; the quantitative calculation on all kinds of dynamic change features of land changes is made by utilizing mathematical model; and the analysis on driving factors of land changes of image is made at last. The research results show that, in recent ten years, the area of cultivated land in Panjin City decreased, the area of vegetation increased, and meanwhile the area of road increased drastically, the settlement place decreased than ever, and water area changed slightly.

Near-Infrared Fluorescent Nanoprobes for Revealing the Role of Dopamine in Drug Addiction.

PubMed

Feng, Peijian; Chen, Yulei; Zhang, Lei; Qian, Cheng-Gen; Xiao, Xuanzhong; Han, Xu; Shen, Qun-Dong

2018-02-07

Brain imaging techniques enable visualizing the activity of central nervous system without invasive neurosurgery. Dopamine is an important neurotransmitter. Its fluctuation in brain leads to a wide range of diseases and disorders, like drug addiction, depression, and Parkinson's disease. We designed near-infrared fluorescence dopamine-responsive nanoprobes (DRNs) for brain activity imaging during drug abuse and addiction process. On the basis of light-induced electron transfer between DRNs and dopamine and molecular wire effect of the DRNs, we can track the dynamical change of the neurotransmitter level in the physiological environment and the releasing of the neurotransmitter in living dopaminergic neurons in response to nicotine stimulation. The functional near-infrared fluorescence imaging can dynamically track the dopamine level in the mice midbrain under normal or drug-activated condition and evaluate the long-term effect of addictive substances to the brain. This strategy has the potential for studying neural activity under physiological condition.

Real-Time Imaging of the Bacillithiol Redox Potential in the Human Pathogen Staphylococcus aureus Using a Genetically Encoded Bacilliredoxin-Fused Redox Biosensor.

PubMed

Loi, Vu Van; Harms, Manuela; Müller, Marret; Huyen, Nguyen Thi Thu; Hamilton, Chris J; Hochgräfe, Falko; Pané-Farré, Jan; Antelmann, Haike

2017-05-20

Bacillithiol (BSH) is utilized as a major thiol-redox buffer in the human pathogen Staphylococcus aureus. Under oxidative stress, BSH forms mixed disulfides with proteins, termed as S-bacillithiolation, which can be reversed by bacilliredoxins (Brx). In eukaryotes, glutaredoxin-fused roGFP2 biosensors have been applied for dynamic live imaging of the glutathione redox potential. Here, we have constructed a genetically encoded bacilliredoxin-fused redox biosensor (Brx-roGFP2) to monitor dynamic changes in the BSH redox potential in S. aureus. The Brx-roGFP2 biosensor showed a specific and rapid response to low levels of bacillithiol disulfide (BSSB) in vitro that required the active-site Cys of Brx. Dynamic live imaging in two methicillin-resistant S. aureus (MRSA) USA300 and COL strains revealed fast and dynamic responses of the Brx-roGFP2 biosensor under hypochlorite and hydrogen peroxide (H 2 O 2 ) stress and constitutive oxidation of the probe in different BSH-deficient mutants. Furthermore, we found that the Brx-roGFP2 expression level and the dynamic range are higher in S. aureus COL compared with the USA300 strain. In phagocytosis assays with THP-1 macrophages, the biosensor was 87% oxidized in S. aureus COL. However, no changes in the BSH redox potential were measured after treatment with different antibiotics classes, indicating that antibiotics do not cause oxidative stress in S. aureus. Conclusion and Innovation: This Brx-roGFP2 biosensor catalyzes specific equilibration between the BSH and roGFP2 redox couples and can be applied for dynamic live imaging of redox changes in S. aureus and other BSH-producing Firmicutes. Antioxid. Redox Signal. 26, 835-848.

Spinning Disk Confocal Imaging of Neutrophil Migration in Zebrafish

PubMed Central

Lam, Pui-ying; Fischer, Robert S; Shin, William D.; Waterman, Clare M; Huttenlocher, Anna

2014-01-01

Live-cell imaging techniques have been substantially improved due to advances in confocal microscopy instrumentation coupled with ultrasensitive detectors. The spinning disk confocal system is capable of generating images of fluorescent live samples with broad dynamic range and high temporal and spatial resolution. The ability to acquire fluorescent images of living cells in vivo on a millisecond timescale allows the dissection of biological processes that have not previously been visualized in a physiologically relevant context. In vivo imaging of rapidly moving cells such as neutrophils can be technically challenging. In this chapter, we describe the practical aspects of imaging neutrophils in zebrafish embryos using spinning disk confocal microscopy. Similar setups can also be applied to image other motile cell types and signaling processes in translucent animals or tissues. PMID:24504955

Minimum Requirements for Taxicab Security Cameras.

PubMed

Zeng, Shengke; Amandus, Harlan E; Amendola, Alfred A; Newbraugh, Bradley H; Cantis, Douglas M; Weaver, Darlene

2014-07-01

The homicide rate of taxicab-industry is 20 times greater than that of all workers. A NIOSH study showed that cities with taxicab-security cameras experienced significant reduction in taxicab driver homicides. Minimum technical requirements and a standard test protocol for taxicab-security cameras for effective taxicab-facial identification were determined. The study took more than 10,000 photographs of human-face charts in a simulated-taxicab with various photographic resolutions, dynamic ranges, lens-distortions, and motion-blurs in various light and cab-seat conditions. Thirteen volunteer photograph-evaluators evaluated these face photographs and voted for the minimum technical requirements for taxicab-security cameras. Five worst-case scenario photographic image quality thresholds were suggested: the resolution of XGA-format, highlight-dynamic-range of 1 EV, twilight-dynamic-range of 3.3 EV, lens-distortion of 30%, and shutter-speed of 1/30 second. These minimum requirements will help taxicab regulators and fleets to identify effective taxicab-security cameras, and help taxicab-security camera manufacturers to improve the camera facial identification capability.

Super-duper chemiluminescent proteins applicable to wide range of bioimaging

NASA Astrophysics Data System (ADS)

Suzuki, Kazushi; Nagai, Takeharu

2017-02-01

We report five new spectral variants of bright luminescent protein made by concatenation of the brightest luciferase, NanoLuc, with various color hues of fluorescent proteins. These proteins, which we call enhanced Nano-lanterns (eNLs), allow five-color live-cell imaging without external light illumination as well as detection of single molecules. Furthermore, eNL-based Ca2+ indicators could be used to image long-term Ca2+ dynamics in iPS-derived cardiomyocytes.

Wavelength-Scanning SPR Imaging Sensors Based on an Acousto-Optic Tunable Filter and a White Light Laser

PubMed Central

Zeng, Youjun; Wang, Lei; Wu, Shu-Yuen; He, Jianan; Qu, Junle; Li, Xuejin; Ho, Ho-Pui; Gu, Dayong; Gao, Bruce Zhi; Shao, Yonghong

2017-01-01

A fast surface plasmon resonance (SPR) imaging biosensor system based on wavelength interrogation using an acousto-optic tunable filter (AOTF) and a white light laser is presented. The system combines the merits of a wide-dynamic detection range and high sensitivity offered by the spectral approach with multiplexed high-throughput data collection and a two-dimensional (2D) biosensor array. The key feature is the use of AOTF to realize wavelength scan from a white laser source and thus to achieve fast tracking of the SPR dip movement caused by target molecules binding to the sensor surface. Experimental results show that the system is capable of completing a SPR dip measurement within 0.35 s. To the best of our knowledge, this is the fastest time ever reported in the literature for imaging spectral interrogation. Based on a spectral window with a width of approximately 100 nm, a dynamic detection range and resolution of 4.63 × 10−2 refractive index unit (RIU) and 1.27 × 10−6 RIU achieved in a 2D-array sensor is reported here. The spectral SPR imaging sensor scheme has the capability of performing fast high-throughput detection of biomolecular interactions from 2D sensor arrays. The design has no mechanical moving parts, thus making the scheme completely solid-state. PMID:28067766

Column-parallel correlated multiple sampling circuits for CMOS image sensors and their noise reduction effects.

PubMed

Suh, Sungho; Itoh, Shinya; Aoyama, Satoshi; Kawahito, Shoji

2010-01-01

For low-noise complementary metal-oxide-semiconductor (CMOS) image sensors, the reduction of pixel source follower noises is becoming very important. Column-parallel high-gain readout circuits are useful for low-noise CMOS image sensors. This paper presents column-parallel high-gain signal readout circuits, correlated multiple sampling (CMS) circuits and their noise reduction effects. In the CMS, the gain of the noise cancelling is controlled by the number of samplings. It has a similar effect to that of an amplified CDS for the thermal noise but is a little more effective for 1/f and RTS noises. Two types of the CMS with simple integration and folding integration are proposed. In the folding integration, the output signal swing is suppressed by a negative feedback using a comparator and one-bit D-to-A converter. The CMS circuit using the folding integration technique allows to realize a very low-noise level while maintaining a wide dynamic range. The noise reduction effects of their circuits have been investigated with a noise analysis and an implementation of a 1Mpixel pinned photodiode CMOS image sensor. Using 16 samplings, dynamic range of 59.4 dB and noise level of 1.9 e(-) for the simple integration CMS and 75 dB and 2.2 e(-) for the folding integration CMS, respectively, are obtained.

Mapping tissue shear modulus on Thiel soft-embalmed mouse skin with shear wave optical coherence elastography

NASA Astrophysics Data System (ADS)

Song, Shaozhen; Joy, Joyce; Wang, Ruikang K.; Huang, Zhihong

2015-03-01

A quantitative measurement of the mechanical properties of biological tissue is a useful assessment of its physiologic conditions, which may aid medical diagnosis and treatment of, e.g., scleroderma and skin cancer. Traditional elastography techniques such as magnetic resonance elastography and ultrasound elastography have limited scope of application on skin due to insufficient spatial resolution. Recently, dynamic / transient elastography are attracting more applications with the advantage of non-destructive measurements, and revealing the absolute moduli values of tissue mechanical properties. Shear wave optical coherence elastography (SW-OCE) is a novel transient elastography method, which lays emphasis on the propagation of dynamic mechanical waves. In this study, high speed shear wave imaging technique was applied to a range of soft-embalmed mouse skin, where 3 kHz shear waves were launched with a piezoelectric actuator as an external excitation. The shear wave velocity was estimated from the shear wave images, and used to recover a shear modulus map in the same OCT imaging range. Results revealed significant difference in shear modulus and structure in compliance with gender, and images on fresh mouse skin are also compared. Thiel embalming technique is also proven to present the ability to furthest preserve the mechanical property of biological tissue. The experiment results suggest that SW-OCE is an effective technique for quantitative estimation of skin tissue biomechanical status.

A three-wavelength multi-channel brain functional imager based on digital lock-in photon-counting technique

NASA Astrophysics Data System (ADS)

Ding, Xuemei; Wang, Bingyuan; Liu, Dongyuan; Zhang, Yao; He, Jie; Zhao, Huijuan; Gao, Feng

2018-02-01

During the past two decades there has been a dramatic rise in the use of functional near-infrared spectroscopy (fNIRS) as a neuroimaging technique in cognitive neuroscience research. Diffuse optical tomography (DOT) and optical topography (OT) can be employed as the optical imaging techniques for brain activity investigation. However, most current imagers with analogue detection are limited by sensitivity and dynamic range. Although photon-counting detection can significantly improve detection sensitivity, the intrinsic nature of sequential excitations reduces temporal resolution. To improve temporal resolution, sensitivity and dynamic range, we develop a multi-channel continuous-wave (CW) system for brain functional imaging based on a novel lock-in photon-counting technique. The system consists of 60 Light-emitting device (LED) sources at three wavelengths of 660nm, 780nm and 830nm, which are modulated by current-stabilized square-wave signals at different frequencies, and 12 photomultiplier tubes (PMT) based on lock-in photon-counting technique. This design combines the ultra-high sensitivity of the photon-counting technique with the parallelism of the digital lock-in technique. We can therefore acquire the diffused light intensity for all the source-detector pairs (SD-pairs) in parallel. The performance assessments of the system are conducted using phantom experiments, and demonstrate its excellent measurement linearity, negligible inter-channel crosstalk, strong noise robustness and high temporal resolution.

Direct torsional actuation of microcantilevers using magnetic excitation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gosvami, Nitya Nand; Nalam, Prathima C.; Tam, Qizhan

2014-09-01

Torsional mode dynamic force microscopy can be used for a wide range of studies including mapping lateral contact stiffness, torsional frequency or amplitude modulation imaging, and dynamic friction measurements of various materials. Piezo-actuation of the cantilever is commonly used, but it introduces spurious resonances, limiting the frequency range that can be sampled, and rendering the technique particularly difficult to apply in liquid medium where the cantilever oscillations are significantly damped. Here, we demonstrate a method that enables direct torsional actuation of cantilevers with high uniformity over wide frequency ranges by attaching a micrometer-scale magnetic bead on the back side ofmore » the cantilever. We show that when beads are magnetized along the width of the cantilever, efficient torsional actuation of the cantilevers can be achieved using a magnetic field produced from a solenoid placed underneath the sample. We demonstrate the capability of this technique by imaging atomic steps on graphite surfaces in tapping mode near the first torsional resonance of the cantilever in dodecane. The technique is also applied to map the variations in the lateral contact stiffness on the surface of graphite and polydiacetylene monolayers.« less

The Focusing Optics X-ray Solar Imager Small Explorer Concept Mission

NASA Astrophysics Data System (ADS)

Christe, Steven; Shih, Albert Y.; Dennis, Brian R.; Glesener, Lindsay; Krucker, Sam; Saint-Hilaire, Pascal; Gubarev, Mikhail; Ramsey, Brian

2016-05-01

We present the FOXSI (Focusing Optics X-ray Solar Imager) small explorer (SMEX) concept, a mission dedicated to studying particle acceleration and energy release on the Sun. FOXSI is designed as a 3-axis stabilized spacecraft in low-Earth orbit making use of state-of-the-art grazing incidence focusing optics combined withpixelated solid-state detectors, allowing for direct imaging of solar X-rays. The current design being studied features multiple telescopes with a 14 meter focal length enabled by a deployable boom.FOXSI will observe the Sun in the 3-100 keV energy range. The FOXSI imaging concept has already been tested on two sounding rocket flights, in 2012 and 2014 and on the HEROES balloon payload flight in 2013. FOXSI will image the Sun with an angular resolution of 5'', a spectral resolution of 0.5 keV, and sub-second temporal resolution. FOXSI is a direct imaging spectrometer with high dynamic range and sensitivity and will provide a brand-new perspective on energy release on the Sun. We describe the mission and its science objectives.

Cine CT technique for dynamic airway studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ell, S.R.; Jolles, H.; Keyes, W.D.

1985-07-01

The advent of cine CT scanning with its 50-msec data acquisition time promises a much wider range of dynamic CT studies. The authors describe a method for dynamic evaluation of the extrathoracic airway, which they believe has considerable potential application in nonfixed upper-airway disease, such as sleep apnea and stridor of unknown cause. Conventional CT is limited in such studies by long data acquisition time and can be used to study only prolonged maneuvers such as phonation. Fluoroscopy and digital subtraction studies are limited by relatively high radiation dose and inability to image all wall motions simultaneously.

Toward autonomous avian-inspired grasping for micro aerial vehicles.

PubMed

Thomas, Justin; Loianno, Giuseppe; Polin, Joseph; Sreenath, Koushil; Kumar, Vijay

2014-06-01

Micro aerial vehicles, particularly quadrotors, have been used in a wide range of applications. However, the literature on aerial manipulation and grasping is limited and the work is based on quasi-static models. In this paper, we draw inspiration from agile, fast-moving birds such as raptors, that are able to capture moving prey on the ground or in water, and develop similar capabilities for quadrotors. We address dynamic grasping, an approach to prehensile grasping in which the dynamics of the robot and its gripper are significant and must be explicitly modeled and controlled for successful execution. Dynamic grasping is relevant for fast pick-and-place operations, transportation and delivery of objects, and placing or retrieving sensors. We show how this capability can be realized (a) using a motion capture system and (b) without external sensors relying only on onboard sensors. In both cases we describe the dynamic model, and trajectory planning and control algorithms. In particular, we present a methodology for flying and grasping a cylindrical object using feedback from a monocular camera and an inertial measurement unit onboard the aerial robot. This is accomplished by mapping the dynamics of the quadrotor to a level virtual image plane, which in turn enables dynamically-feasible trajectory planning for image features in the image space, and a vision-based controller with guaranteed convergence properties. We also present experimental results obtained with a quadrotor equipped with an articulated gripper to illustrate both approaches.

Iterative-Transform Phase Retrieval Using Adaptive Diversity

NASA Technical Reports Server (NTRS)

Dean, Bruce H.

2007-01-01

A phase-diverse iterative-transform phase-retrieval algorithm enables high spatial-frequency, high-dynamic-range, image-based wavefront sensing. [The terms phase-diverse, phase retrieval, image-based, and wavefront sensing are defined in the first of the two immediately preceding articles, Broadband Phase Retrieval for Image-Based Wavefront Sensing (GSC-14899-1).] As described below, no prior phase-retrieval algorithm has offered both high dynamic range and the capability to recover high spatial-frequency components. Each of the previously developed image-based phase-retrieval techniques can be classified into one of two categories: iterative transform or parametric. Among the modifications of the original iterative-transform approach has been the introduction of a defocus diversity function (also defined in the cited companion article). Modifications of the original parametric approach have included minimizing alternative objective functions as well as implementing a variety of nonlinear optimization methods. The iterative-transform approach offers the advantage of ability to recover low, middle, and high spatial frequencies, but has disadvantage of having a limited dynamic range to one wavelength or less. In contrast, parametric phase retrieval offers the advantage of high dynamic range, but is poorly suited for recovering higher spatial frequency aberrations. The present phase-diverse iterative transform phase-retrieval algorithm offers both the high-spatial-frequency capability of the iterative-transform approach and the high dynamic range of parametric phase-recovery techniques. In implementation, this is a focus-diverse iterative-transform phaseretrieval algorithm that incorporates an adaptive diversity function, which makes it possible to avoid phase unwrapping while preserving high-spatial-frequency recovery. The algorithm includes an inner and an outer loop (see figure). An initial estimate of phase is used to start the algorithm on the inner loop, wherein multiple intensity images are processed, each using a different defocus value. The processing is done by an iterative-transform method, yielding individual phase estimates corresponding to each image of the defocus-diversity data set. These individual phase estimates are combined in a weighted average to form a new phase estimate, which serves as the initial phase estimate for either the next iteration of the iterative-transform method or, if the maximum number of iterations has been reached, for the next several steps, which constitute the outerloop portion of the algorithm. The details of the next several steps must be omitted here for the sake of brevity. The overall effect of these steps is to adaptively update the diversity defocus values according to recovery of global defocus in the phase estimate. Aberration recovery varies with differing amounts as the amount of diversity defocus is updated in each image; thus, feedback is incorporated into the recovery process. This process is iterated until the global defocus error is driven to zero during the recovery process. The amplitude of aberration may far exceed one wavelength after completion of the inner-loop portion of the algorithm, and the classical iterative transform method does not, by itself, enable recovery of multi-wavelength aberrations. Hence, in the absence of a means of off-loading the multi-wavelength portion of the aberration, the algorithm would produce a wrapped phase map. However, a special aberration-fitting procedure can be applied to the wrapped phase data to transfer at least some portion of the multi-wavelength aberration to the diversity function, wherein the data are treated as known phase values. In this way, a multiwavelength aberration can be recovered incrementally by successively applying the aberration-fitting procedure to intermediate wrapped phase maps. During recovery, as more of the aberration is transferred to the diversity function following successive iterations around the ter loop, the estimated phase ceases to wrap in places where the aberration values become incorporated as part of the diversity function. As a result, as the aberration content is transferred to the diversity function, the phase estimate resembles that of a reference flat.

Live imaging of rat embryos with Doppler swept-source optical coherence tomography

NASA Astrophysics Data System (ADS)

Larina, Irina V.; Furushima, Kenryo; Dickinson, Mary E.; Behringer, Richard R.; Larin, Kirill V.

2009-09-01

The rat has long been considered an excellent system to study mammalian embryonic cardiovascular physiology, but has lacked the extensive genetic tools available in the mouse to be able to create single gene mutations. However, the recent establishment of rat embryonic stem cell lines facilitates the generation of new models in the rat embryo to link changes in physiology with altered gene function to define the underlying mechanisms behind congenital cardiovascular birth defects. Along with the ability to create new rat genotypes there is a strong need for tools to analyze phenotypes with high spatial and temporal resolution. Doppler OCT has been previously used for 3-D structural analysis and blood flow imaging in other model species. We use Doppler swept-source OCT for live imaging of early postimplantation rat embryos. Structural imaging is used for 3-D reconstruction of embryo morphology and dynamic imaging of the beating heart and vessels, while Doppler-mode imaging is used to visualize blood flow. We demonstrate that Doppler swept-source OCT can provide essential information about the dynamics of early rat embryos and serve as a basis for a wide range of studies on functional evaluation of rat embryo physiology.

Live imaging of rat embryos with Doppler swept-source optical coherence tomography

PubMed Central

Larina, Irina V.; Furushima, Kenryo; Dickinson, Mary E.; Behringer, Richard R.; Larin, Kirill V.

2009-01-01

The rat has long been considered an excellent system to study mammalian embryonic cardiovascular physiology, but has lacked the extensive genetic tools available in the mouse to be able to create single gene mutations. However, the recent establishment of rat embryonic stem cell lines facilitates the generation of new models in the rat embryo to link changes in physiology with altered gene function to define the underlying mechanisms behind congenital cardiovascular birth defects. Along with the ability to create new rat genotypes there is a strong need for tools to analyze phenotypes with high spatial and temporal resolution. Doppler OCT has been previously used for 3-D structural analysis and blood flow imaging in other model species. We use Doppler swept-source OCT for live imaging of early postimplantation rat embryos. Structural imaging is used for 3-D reconstruction of embryo morphology and dynamic imaging of the beating heart and vessels, while Doppler-mode imaging is used to visualize blood flow. We demonstrate that Doppler swept-source OCT can provide essential information about the dynamics of early rat embryos and serve as a basis for a wide range of studies on functional evaluation of rat embryo physiology. PMID:19895102

Detailed magnetic resonance imaging features of a case series of primary gliosarcoma.

PubMed

Sampaio, Luísa; Linhares, Paulo; Fonseca, José

2017-12-01

Objective We aimed to characterise the magnetic resonance imaging (MRI) features of a case series of primary gliosarcoma, with the inclusion of diffusion-weighted imaging and perfusion imaging with dynamic susceptibility contrast MRI. Materials and methods We conducted a retrospective study of cases of primary gliosarcoma from the Pathology Department database from January 2006 to December 2014. Clinical and demographic data were obtained. Two neuroradiologists, blinded to diagnosis, assessed tumour location, signal intensity in T1 and T2-weighted images, pattern of enhancement, diffusion-weighted imaging and dynamic susceptibility contrast MRI studies on preoperative MRI. Results Seventeen patients with primary gliosarcomas had preoperative MRI study: seven men and 10 women, with a mean age of 59 years (range 27-74). All lesions were well demarcated, supratentorial and solitary (frontal n = 5, temporal n = 4, parietal n = 3); 13 tumours abutted the dural surface (8/13 with dural enhancement); T1 and T2-weighted imaging patterns were heterogeneous and the majority of lesions (12/17) showed a rim-like enhancement pattern with focal nodularities/irregular thickness. Restricted diffusion (mean apparent diffusion coefficient values 0.64 × 10 -3 mm 2 /s) in the more solid/thick components was present in eight out of 11 patients with diffusion-weighted imaging study. Dynamic susceptibility contrast MRI study ( n = 8) consistently showed hyperperfusion in non-necrotic/cystic components on relative cerebral volume maps. Conclusions The main distinguishing features of primary gliosarcoma are supratentorial and peripheral location, well-defined boundaries and a rim-like pattern of enhancement with an irregular thick wall. Diffusion-weighted imaging and relative cerebral volume map analysis paralleled primary gliosarcoma with high-grade gliomas, thus proving helpful in differential diagnosis.

Flow-induced Flutter of Heart Valves: Experiments with Canonical Models

NASA Astrophysics Data System (ADS)

Dou, Zhongwang; Seo, Jung-Hee; Mittal, Rajat

2017-11-01

For the better understanding of hemodynamics associated with valvular function in health and disease, the flow-induced flutter of heart valve leaflets is studied using benchtop experiments with canonical valve models. A simple experimental model with flexible leaflets is constructed and a pulsatile pump drives the flow through the leaflets. We quantify the leaflet dynamics using digital image analysis and also characterize the dynamics of the flow around the leaflets using particle imaging velocimetry. Experiments are conducted over a wide range of flow and leaflet parameters and data curated for use as a benchmark for validation of computational fluid-structure interaction models. The authors would like to acknowledge Supported from NSF Grants IIS-1344772, CBET-1511200 and NSF XSEDE Grant TG-CTS100002.

Using superconducting undulator for enhanced imaging capabilities of MaRIE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yampolsky, Nikolai

MaRIE x-ray free electron laser (FEL) is envisioned to deliver a burst of closely spaced in time pulses for enabling the capability of studying the dynamic processes in a sample. MaRIE capability can be largely enhanced using the superconducting undulator, which has the capability of doubling its period. This technology will allow reaching the photon energy as low as ~200-500 eV. As a result, the MaRIE facility will have a broader photon energy range enabling a larger variety of experiments. The soft x-ray capability is more likely to achieve the 3D imaging of dynamic processes in noncrystal materials than themore » hard x-ray capability alone.« less

The TRICLOBS Dynamic Multi-Band Image Data Set for the Development and Evaluation of Image Fusion Methods

PubMed Central

Hogervorst, Maarten A.; Pinkus, Alan R.

2016-01-01

The fusion and enhancement of multiband nighttime imagery for surveillance and navigation has been the subject of extensive research for over two decades. Despite the ongoing efforts in this area there is still only a small number of static multiband test images available for the development and evaluation of new image fusion and enhancement methods. Moreover, dynamic multiband imagery is also currently lacking. To fill this gap we present the TRICLOBS dynamic multi-band image data set containing sixteen registered visual (0.4–0.7μm), near-infrared (NIR, 0.7–1.0μm) and long-wave infrared (LWIR, 8–14μm) motion sequences. They represent different military and civilian surveillance scenarios registered in three different scenes. Scenes include (military and civilian) people that are stationary, walking or running, or carrying various objects. Vehicles, foliage, and buildings or other man-made structures are also included in the scenes. This data set is primarily intended for the development and evaluation of image fusion, enhancement and color mapping algorithms for short-range surveillance applications. The imagery was collected during several field trials with our newly developed TRICLOBS (TRI-band Color Low-light OBServation) all-day all-weather surveillance system. This system registers a scene in the Visual, NIR and LWIR part of the electromagnetic spectrum using three optically aligned sensors (two digital image intensifiers and an uncooled long-wave infrared microbolometer). The three sensor signals are mapped to three individual RGB color channels, digitized, and stored as uncompressed RGB (false) color frames. The TRICLOBS data set enables the development and evaluation of (both static and dynamic) image fusion, enhancement and color mapping algorithms. To allow the development of realistic color remapping procedures, the data set also contains color photographs of each of the three scenes. The color statistics derived from these photographs can be used to define color mappings that give the multi-band imagery a realistic color appearance. PMID:28036328

The TRICLOBS Dynamic Multi-Band Image Data Set for the Development and Evaluation of Image Fusion Methods.

PubMed

Toet, Alexander; Hogervorst, Maarten A; Pinkus, Alan R

2016-01-01

The fusion and enhancement of multiband nighttime imagery for surveillance and navigation has been the subject of extensive research for over two decades. Despite the ongoing efforts in this area there is still only a small number of static multiband test images available for the development and evaluation of new image fusion and enhancement methods. Moreover, dynamic multiband imagery is also currently lacking. To fill this gap we present the TRICLOBS dynamic multi-band image data set containing sixteen registered visual (0.4-0.7μm), near-infrared (NIR, 0.7-1.0μm) and long-wave infrared (LWIR, 8-14μm) motion sequences. They represent different military and civilian surveillance scenarios registered in three different scenes. Scenes include (military and civilian) people that are stationary, walking or running, or carrying various objects. Vehicles, foliage, and buildings or other man-made structures are also included in the scenes. This data set is primarily intended for the development and evaluation of image fusion, enhancement and color mapping algorithms for short-range surveillance applications. The imagery was collected during several field trials with our newly developed TRICLOBS (TRI-band Color Low-light OBServation) all-day all-weather surveillance system. This system registers a scene in the Visual, NIR and LWIR part of the electromagnetic spectrum using three optically aligned sensors (two digital image intensifiers and an uncooled long-wave infrared microbolometer). The three sensor signals are mapped to three individual RGB color channels, digitized, and stored as uncompressed RGB (false) color frames. The TRICLOBS data set enables the development and evaluation of (both static and dynamic) image fusion, enhancement and color mapping algorithms. To allow the development of realistic color remapping procedures, the data set also contains color photographs of each of the three scenes. The color statistics derived from these photographs can be used to define color mappings that give the multi-band imagery a realistic color appearance.

Evaluation of High Dynamic Range Photography as a Luminance Mapping Technique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Inanici, Mehlika; Galvin, Jim

2004-12-30

The potential, limitations, and applicability of the High Dynamic Range (HDR) photography technique is evaluated as a luminance mapping tool. Multiple exposure photographs of static scenes are taken with a Nikon 5400 digital camera to capture the wide luminance variation within the scenes. The camera response function is computationally derived using the Photosphere software, and is used to fuse the multiple photographs into HDR images. The vignetting effect and point spread function of the camera and lens system is determined. Laboratory and field studies have shown that the pixel values in the HDR photographs can correspond to the physical quantitymore » of luminance with reasonable precision and repeatability.« less

Optimizing Floating Guard Ring Designs for FASPAX N-in-P Silicon Sensors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shin, Kyung-Wook; Bradford, Robert; Lipton, Ronald

2016-10-06

FASPAX (Fermi-Argonne Semiconducting Pixel Array X-ray detector) is being developed as a fast integrating area detector with wide dynamic range for time resolved applications at the upgraded Advanced Photon Source (APS.) A burst mode detector with intendedmore » $$\\mbox{13 $$MHz$}$ image rate, FASPAX will also incorporate a novel integration circuit to achieve wide dynamic range, from single photon sensitivity to $$10^{\\text{5}}$$ x-rays/pixel/pulse. To achieve these ambitious goals, a novel silicon sensor design is required. This paper will detail early design of the FASPAX sensor. Results from TCAD optimization studies, and characterization of prototype sensors will be presented.« less

Water-Immersible MEMS scanning mirror designed for wide-field fast-scanning photoacoustic microscopy

NASA Astrophysics Data System (ADS)

Yao, Junjie; Huang, Chih-Hsien; Martel, Catherine; Maslov, Konstantin I.; Wang, Lidai; Yang, Joon-Mo; Gao, Liang; Randolph, Gwendalyn; Zou, Jun; Wang, Lihong V.

2013-03-01

By offering images with high spatial resolution and unique optical absorption contrast, optical-resolution photoacoustic microscopy (OR-PAM) has gained increasing attention in biomedical research. Recent developments in OR-PAM have improved its imaging speed, but have sacrificed either the detection sensitivity or field of view or both. We have developed a wide-field fast-scanning OR-PAM by using a water-immersible MEMS scanning mirror (MEMS-ORPAM). Made of silicon with a gold coating, the MEMS mirror plate can reflect both optical and acoustic beams. Because it uses an electromagnetic driving force, the whole MEMS scanning system can be submerged in water. In MEMS-ORPAM, the optical and acoustic beams are confocally configured and simultaneously steered, which ensures uniform detection sensitivity. A B-scan imaging speed as high as 400 Hz can be achieved over a 3 mm scanning range. A diffraction-limited lateral resolution of 2.4 μm in water and a maximum imaging depth of 1.1 mm in soft tissue have been experimentally determined. Using the system, we imaged the flow dynamics of both red blood cells and carbon particles in a mouse ear in vivo. By using Evans blue dye as the contrast agent, we also imaged the flow dynamics of lymphatic vessels in a mouse tail in vivo. The results show that MEMS-OR-PAM could be a powerful tool for studying highly dynamic and time-sensitive biological phenomena.

Proposed imaging of the ultrafast electronic motion in samples using x-ray phase contrast.

PubMed

Dixit, Gopal; Slowik, Jan Malte; Santra, Robin

2013-03-29

Tracing the motion of electrons has enormous relevance to understanding ubiquitous phenomena in ultrafast science, such as the dynamical evolution of the electron density during complex chemical and biological processes. Scattering of ultrashort x-ray pulses from an electronic wave packet would appear to be the most obvious approach to image the electronic motion in real time and real space with the notion that such scattering patterns, in the far-field regime, encode the instantaneous electron density of the wave packet. However, recent results by Dixit et al. [Proc. Natl. Acad. Sci. U.S.A. 109, 11636 (2012)] have put this notion into question and have shown that the scattering in the far-field regime probes spatiotemporal density-density correlations. Here, we propose a possible way to image the instantaneous electron density of the wave packet via ultrafast x-ray phase contrast imaging. Moreover, we show that inelastic scattering processes, which plague ultrafast scattering in the far-field regime, do not contribute in ultrafast x-ray phase contrast imaging as a consequence of an interference effect. We illustrate our general findings by means of a wave packet that lies in the time and energy range of the dynamics of valence electrons in complex molecular and biological systems. This present work offers a potential to image not only instantaneous snapshots of nonstationary electron dynamics, but also the laplacian of these snapshots which provide information about the complex bonding and topology of the charge distributions in the systems.

Proposed Imaging of the Ultrafast Electronic Motion in Samples using X-Ray Phase Contrast

NASA Astrophysics Data System (ADS)

Dixit, Gopal; Slowik, Jan Malte; Santra, Robin

2013-03-01

Tracing the motion of electrons has enormous relevance to understanding ubiquitous phenomena in ultrafast science, such as the dynamical evolution of the electron density during complex chemical and biological processes. Scattering of ultrashort x-ray pulses from an electronic wave packet would appear to be the most obvious approach to image the electronic motion in real time and real space with the notion that such scattering patterns, in the far-field regime, encode the instantaneous electron density of the wave packet. However, recent results by Dixit et al. [Proc. Natl. Acad. Sci. U.S.A. 109, 11 636 (2012)] have put this notion into question and have shown that the scattering in the far-field regime probes spatiotemporal density-density correlations. Here, we propose a possible way to image the instantaneous electron density of the wave packet via ultrafast x-ray phase contrast imaging. Moreover, we show that inelastic scattering processes, which plague ultrafast scattering in the far-field regime, do not contribute in ultrafast x-ray phase contrast imaging as a consequence of an interference effect. We illustrate our general findings by means of a wave packet that lies in the time and energy range of the dynamics of valence electrons in complex molecular and biological systems. This present work offers a potential to image not only instantaneous snapshots of nonstationary electron dynamics, but also the Laplacian of these snapshots which provide information about the complex bonding and topology of the charge distributions in the systems.

First Images from the Focusing Optics X-Ray Solar Imager

NASA Astrophysics Data System (ADS)

Krucker, Säm; Christe, Steven; Glesener, Lindsay; Ishikawa, Shin-nosuke; Ramsey, Brian; Takahashi, Tadayuki; Watanabe, Shin; Saito, Shinya; Gubarev, Mikhail; Kilaru, Kiranmayee; Tajima, Hiroyasu; Tanaka, Takaaki; Turin, Paul; McBride, Stephen; Glaser, David; Fermin, Jose; White, Stephen; Lin, Robert

2014-10-01

The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload flew for the first time on 2012 November 2, producing the first focused images of the Sun above 5 keV. To enable hard X-ray (HXR) imaging spectroscopy via direct focusing, FOXSI makes use of grazing-incidence replicated optics combined with fine-pitch solid-state detectors. On its first flight, FOXSI observed several targets that included active regions, the quiet Sun, and a GOES-class B2.7 microflare. This Letter provides an introduction to the FOXSI instrument and presents its first solar image. These data demonstrate the superiority in sensitivity and dynamic range that is achievable with a direct HXR imager with respect to previous, indirect imaging methods, and illustrate the technological readiness for a spaceborne mission to observe HXRs from solar flares via direct focusing optics.

Enhanced truncated-correlation photothermal coherence tomography with application to deep subsurface defect imaging and 3-dimensional reconstructions

NASA Astrophysics Data System (ADS)

Tavakolian, Pantea; Sivagurunathan, Koneswaran; Mandelis, Andreas

2017-07-01

Photothermal diffusion-wave imaging is a promising technique for non-destructive evaluation and medical applications. Several diffusion-wave techniques have been developed to produce depth-resolved planar images of solids and to overcome imaging depth and image blurring limitations imposed by the physics of parabolic diffusion waves. Truncated-Correlation Photothermal Coherence Tomography (TC-PCT) is the most successful class of these methodologies to-date providing 3-D subsurface visualization with maximum depth penetration and high axial and lateral resolution. To extend the depth range and axial and lateral resolution, an in-depth analysis of TC-PCT, a novel imaging system with improved instrumentation, and an optimized reconstruction algorithm over the original TC-PCT technique is developed. Thermal waves produced by a laser chirped pulsed heat source in a finite thickness solid and the image reconstruction algorithm are investigated from the theoretical point of view. 3-D visualization of subsurface defects utilizing the new TC-PCT system is reported. The results demonstrate that this method is able to detect subsurface defects at the depth range of ˜4 mm in a steel sample, which exhibits dynamic range improvement by a factor of 2.6 compared to the original TC-PCT. This depth does not represent the upper limit of the enhanced TC-PCT. Lateral resolution in the steel sample was measured to be ˜31 μm.

Developments in dynamic MR elastography for in vitro biomechanical assessment of hyaline cartilage under high-frequency cyclical shear.

PubMed

Lopez, Orlando; Amrami, Kimberly K; Manduca, Armando; Rossman, Phillip J; Ehman, Richard L

2007-02-01

The design, construction, and evaluation of a customized dynamic magnetic resonance elastography (MRE) technique for biomechanical assessment of hyaline cartilage in vitro are described. For quantification of the dynamic shear properties of hyaline cartilage by dynamic MRE, mechanical excitation and motion sensitization were performed at frequencies in the kilohertz range. A custom electromechanical actuator and a z-axis gradient coil were used to generate and image shear waves throughout cartilage at 1000-10,000 Hz. A radiofrequency (RF) coil was also constructed for high-resolution imaging. The technique was validated at 4000 and 6000 Hz by quantifying differences in shear stiffness between soft ( approximately 200 kPa) and stiff ( approximately 300 kPa) layers of 5-mm-thick bilayered phantoms. The technique was then used to quantify the dynamic shear properties of bovine and shark hyaline cartilage samples at frequencies up to 9000 Hz. The results demonstrate that one can obtain high-resolution shear stiffness measurements of hyaline cartilage and small, stiff, multilayered phantoms at high frequencies by generating robust mechanical excitations and using large magnetic field gradients. Dynamic MRE can potentially be used to directly quantify the dynamic shear properties of hyaline and articular cartilage, as well as other cartilaginous materials and engineered constructs. (c) 2007 Wiley-Liss, Inc.

Estimating plant area index for monitoring crop growth dynamics using Landsat-8 and RapidEye images

NASA Astrophysics Data System (ADS)

Shang, Jiali; Liu, Jiangui; Huffman, Ted; Qian, Budong; Pattey, Elizabeth; Wang, Jinfei; Zhao, Ting; Geng, Xiaoyuan; Kroetsch, David; Dong, Taifeng; Lantz, Nicholas

2014-01-01

This study investigates the use of two different optical sensors, the multispectral imager (MSI) onboard the RapidEye satellites and the operational land imager (OLI) onboard the Landsat-8 for mapping within-field variability of crop growth conditions and tracking the seasonal growth dynamics. The study was carried out in southern Ontario, Canada, during the 2013 growing season for three annual crops, corn, soybeans, and winter wheat. Plant area index (PAI) was measured at different growth stages using digital hemispherical photography at two corn fields, two winter wheat fields, and two soybean fields. Comparison between several conventional vegetation indices derived from concurrently acquired image data by the two sensors showed a good agreement. The two-band enhanced vegetation index (EVI2) and the normalized difference vegetation index (NDVI) were derived from the surface reflectance of the two sensors. The study showed that EVI2 was more resistant to saturation at high biomass range than NDVI. A linear relationship could be used for crop green effective PAI estimation from EVI2, with a coefficient of determination (R2) of 0.85 and root-mean-square error of 0.53. The estimated multitemporal product of green PAI was found to be able to capture the seasonal dynamics of the three crops.

Compensator design for improved counterbalancing in high speed atomic force microscopy.

PubMed

Bozchalooi, I S; Youcef-Toumi, K; Burns, D J; Fantner, G E

2011-11-01

High speed atomic force microscopy can provide the possibility of many new scientific observations and applications ranging from nano-manufacturing to the study of biological processes. However, the limited imaging speed has been an imperative drawback of the atomic force microscopes. One of the main reasons behind this limitation is the excitation of the AFM dynamics at high scan speeds, severely undermining the reliability of the acquired images. In this research, we propose a piezo based, feedforward controlled, counter actuation mechanism to compensate for the excited out-of-plane scanner dynamics. For this purpose, the AFM controller output is properly filtered via a linear compensator and then applied to a counter actuating piezo. An effective algorithm for estimating the compensator parameters is developed. The information required for compensator design is extracted from the cantilever deflection signal, hence eliminating the need for any additional sensors. The proposed approach is implemented and experimentally evaluated on the dynamic response of a custom made AFM. It is further assessed by comparing the imaging performance of the AFM with and without the application of the proposed technique and in comparison with the conventional counterbalancing methodology. The experimental results substantiate the effectiveness of the method in significantly improving the imaging performance of AFM at high scan speeds. © 2011 American Institute of Physics

Compensator design for improved counterbalancing in high speed atomic force microscopy

PubMed Central

Bozchalooi, I. S.; Youcef-Toumi, K.; Burns, D. J.; Fantner, G. E.

2011-01-01

High speed atomic force microscopy can provide the possibility of many new scientific observations and applications ranging from nano-manufacturing to the study of biological processes. However, the limited imaging speed has been an imperative drawback of the atomic force microscopes. One of the main reasons behind this limitation is the excitation of the AFM dynamics at high scan speeds, severely undermining the reliability of the acquired images. In this research, we propose a piezo based, feedforward controlled, counter actuation mechanism to compensate for the excited out-of-plane scanner dynamics. For this purpose, the AFM controller output is properly filtered via a linear compensator and then applied to a counter actuating piezo. An effective algorithm for estimating the compensator parameters is developed. The information required for compensator design is extracted from the cantilever deflection signal, hence eliminating the need for any additional sensors. The proposed approach is implemented and experimentally evaluated on the dynamic response of a custom made AFM. It is further assessed by comparing the imaging performance of the AFM with and without the application of the proposed technique and in comparison with the conventional counterbalancing methodology. The experimental results substantiate the effectiveness of the method in significantly improving the imaging performance of AFM at high scan speeds. PMID:22128989

Compensator design for improved counterbalancing in high speed atomic force microscopy

NASA Astrophysics Data System (ADS)

Bozchalooi, I. S.; Youcef-Toumi, K.; Burns, D. J.; Fantner, G. E.

2011-11-01

High speed atomic force microscopy can provide the possibility of many new scientific observations and applications ranging from nano-manufacturing to the study of biological processes. However, the limited imaging speed has been an imperative drawback of the atomic force microscopes. One of the main reasons behind this limitation is the excitation of the AFM dynamics at high scan speeds, severely undermining the reliability of the acquired images. In this research, we propose a piezo based, feedforward controlled, counter actuation mechanism to compensate for the excited out-of-plane scanner dynamics. For this purpose, the AFM controller output is properly filtered via a linear compensator and then applied to a counter actuating piezo. An effective algorithm for estimating the compensator parameters is developed. The information required for compensator design is extracted from the cantilever deflection signal, hence eliminating the need for any additional sensors. The proposed approach is implemented and experimentally evaluated on the dynamic response of a custom made AFM. It is further assessed by comparing the imaging performance of the AFM with and without the application of the proposed technique and in comparison with the conventional counterbalancing methodology. The experimental results substantiate the effectiveness of the method in significantly improving the imaging performance of AFM at high scan speeds.

Quantitative assessment of dynamic PET imaging data in cancer imaging.

PubMed

Muzi, Mark; O'Sullivan, Finbarr; Mankoff, David A; Doot, Robert K; Pierce, Larry A; Kurland, Brenda F; Linden, Hannah M; Kinahan, Paul E

2012-11-01

Clinical imaging in positron emission tomography (PET) is often performed using single-time-point estimates of tracer uptake or static imaging that provides a spatial map of regional tracer concentration. However, dynamic tracer imaging can provide considerably more information about in vivo biology by delineating both the temporal and spatial pattern of tracer uptake. In addition, several potential sources of error that occur in static imaging can be mitigated. This review focuses on the application of dynamic PET imaging to measuring regional cancer biologic features and especially in using dynamic PET imaging for quantitative therapeutic response monitoring for cancer clinical trials. Dynamic PET imaging output parameters, particularly transport (flow) and overall metabolic rate, have provided imaging end points for clinical trials at single-center institutions for years. However, dynamic imaging poses many challenges for multicenter clinical trial implementations from cross-center calibration to the inadequacy of a common informatics infrastructure. Underlying principles and methodology of PET dynamic imaging are first reviewed, followed by an examination of current approaches to dynamic PET image analysis with a specific case example of dynamic fluorothymidine imaging to illustrate the approach. Copyright © 2012 Elsevier Inc. All rights reserved.

LLSURE: local linear SURE-based edge-preserving image filtering.

PubMed

Qiu, Tianshuang; Wang, Aiqi; Yu, Nannan; Song, Aimin

2013-01-01

In this paper, we propose a novel approach for performing high-quality edge-preserving image filtering. Based on a local linear model and using the principle of Stein's unbiased risk estimate as an estimator for the mean squared error from the noisy image only, we derive a simple explicit image filter which can filter out noise while preserving edges and fine-scale details. Moreover, this filter has a fast and exact linear-time algorithm whose computational complexity is independent of the filtering kernel size; thus, it can be applied to real time image processing tasks. The experimental results demonstrate the effectiveness of the new filter for various computer vision applications, including noise reduction, detail smoothing and enhancement, high dynamic range compression, and flash/no-flash denoising.

Studies of superresolution range-Doppler imaging

NASA Astrophysics Data System (ADS)

Zhu, Zhaoda; Ye, Zhenru; Wu, Xiaoqing; Yin, Jun; She, Zhishun

1993-02-01

This paper presents three superresolution imaging methods, including the linear prediction data extrapolation DFT (LPDEDFT), the dynamic optimization linear least squares (DOLLS), and the Hopfield neural network nonlinear least squares (HNNNLS). Live data of a metalized scale model B-52 aircraft, mounted on a rotating platform in a microwave anechoic chamber, have in this way been processed, as has a flying Boeing-727 aircraft. The imaging results indicate that, compared to the conventional Fourier method, either higher resolution for the same effective bandwidth of transmitted signals and total rotation angle in imaging, or equal-quality images from smaller bandwidth and total rotation, angle may be obtained by these superresolution approaches. Moreover, these methods are compared in respect of their resolution capability and computational complexity.

The Research on Lucalibration of GF-4 Satellite

NASA Astrophysics Data System (ADS)

Qi, W.; Tan, W.

2018-04-01

Starting from the lunar observation requirements of the GF-4 satellite, the main index such as the resolution, the imaging field, the reflect radiance and the imaging integration time are analyzed combined with the imaging features and parameters of this camera. The analysis results show that the lunar observation of GF-4 satellite has high resolution, wide field which can image the whole moon, the radiance of the pupil which is reflected by the moon is within the dynamic range of the camera, and the lunar image quality can be guaranteed better by setting up a reasonable integration time. At the same time, the radiation transmission model of the lunar radiation calibration is trace and the radiation degree is evaluated.

A review on brightness preserving contrast enhancement methods for digital image

NASA Astrophysics Data System (ADS)

Rahman, Md Arifur; Liu, Shilong; Li, Ruowei; Wu, Hongkun; Liu, San Chi; Jahan, Mahmuda Rawnak; Kwok, Ngaiming

2018-04-01

Image enhancement is an imperative step for many vision based applications. For image contrast enhancement, popular methods adopt the principle of spreading the captured intensities throughout the allowed dynamic range according to predefined distributions. However, these algorithms take little or no consideration into account of maintaining the mean brightness of the original scene, which is of paramount importance to carry the true scene illumination characteristics to the viewer. Though there have been significant amount of reviews on contrast enhancement methods published, updated review on overall brightness preserving image enhancement methods is still scarce. In this paper, a detailed survey is performed on those particular methods that specifically aims to maintain the overall scene illumination characteristics while enhancing the digital image.

Neural field model to reconcile structure with function in primary visual cortex.

PubMed

Rankin, James; Chavane, Frédéric

2017-10-01

Voltage-sensitive dye imaging experiments in primary visual cortex (V1) have shown that local, oriented visual stimuli elicit stable orientation-selective activation within the stimulus retinotopic footprint. The cortical activation dynamically extends far beyond the retinotopic footprint, but the peripheral spread stays non-selective-a surprising finding given a number of anatomo-functional studies showing the orientation specificity of long-range connections. Here we use a computational model to investigate this apparent discrepancy by studying the expected population response using known published anatomical constraints. The dynamics of input-driven localized states were simulated in a planar neural field model with multiple sub-populations encoding orientation. The realistic connectivity profile has parameters controlling the clustering of long-range connections and their orientation bias. We found substantial overlap between the anatomically relevant parameter range and a steep decay in orientation selective activation that is consistent with the imaging experiments. In this way our study reconciles the reported orientation bias of long-range connections with the functional expression of orientation selective neural activity. Our results demonstrate this sharp decay is contingent on three factors, that long-range connections are sufficiently diffuse, that the orientation bias of these connections is in an intermediate range (consistent with anatomy) and that excitation is sufficiently balanced by inhibition. Conversely, our modelling results predict that, for reduced inhibition strength, spurious orientation selective activation could be generated through long-range lateral connections. Furthermore, if the orientation bias of lateral connections is very strong, or if inhibition is particularly weak, the network operates close to an instability leading to unbounded cortical activation.

A Dual Modality System for Simultaneous Fluorescence and Positron Emission Tomography Imaging of Small Animals

NASA Astrophysics Data System (ADS)

Liu, Shuangquan; Zhang, Bin; Wang, Xin; Li, Lin; Chen, Yan; Liu, Xin; Liu, Fei; Shan, Baoci; Bai, Jing

2011-02-01

A dual-modality imaging system for simultaneous fluorescence molecular tomography (FMT) and positron emission tomography (PET) of small animals has been developed. The system consists of a noncontact 360°-projection FMT module and a flat panel detector pair based PET module, which are mounted orthogonally for the sake of eliminating cross interference. The FMT images and PET data are simultaneously acquired by employing dynamic sampling mode. Phantom experiments, in which the localization and range of radioactive and fluorescence probes are exactly indicated, have been carried out to verify the feasibility of the system. An experimental tumor-bearing mouse is also scanned using the dual-modality simultaneous imaging system, the preliminary fluorescence tomographic images and PET images demonstrate the in vivo performance of the presented dual-modality system.

An improved artifact removal in exposure fusion with local linear constraints

NASA Astrophysics Data System (ADS)

Zhang, Hai; Yu, Mali

2018-04-01

In exposure fusion, it is challenging to remove artifacts because of camera motion and moving objects in the scene. An improved artifact removal method is proposed in this paper, which performs local linear adjustment in artifact removal progress. After determining a reference image, we first perform high-dynamic-range (HDR) deghosting to generate an intermediate image stack from the input image stack. Then, a linear Intensity Mapping Function (IMF) in each window is extracted based on the intensities of intermediate image and reference image, the intensity mean and variance of reference image. Finally, with the extracted local linear constraints, we reconstruct a target image stack, which can be directly used for fusing a single HDR-like image. Some experiments have been implemented and experimental results demonstrate that the proposed method is robust and effective in removing artifacts especially in the saturated regions of the reference image.

High resolution, wide field of view, real time 340GHz 3D imaging radar for security screening

NASA Astrophysics Data System (ADS)

Robertson, Duncan A.; Macfarlane, David G.; Hunter, Robert I.; Cassidy, Scott L.; Llombart, Nuria; Gandini, Erio; Bryllert, Tomas; Ferndahl, Mattias; Lindström, Hannu; Tenhunen, Jussi; Vasama, Hannu; Huopana, Jouni; Selkälä, Timo; Vuotikka, Antti-Jussi

2017-05-01

The EU FP7 project CONSORTIS (Concealed Object Stand-Off Real-Time Imaging for Security) is developing a demonstrator system for next generation airport security screening which will combine passive and active submillimeter wave imaging sensors. We report on the development of the 340 GHz 3D imaging radar which achieves high volumetric resolution over a wide field of view with high dynamic range and a high frame rate. A sparse array of 16 radar transceivers is coupled with high speed mechanical beam scanning to achieve a field of view of 1 x 1 x 1 m3 and a 10 Hz frame rate.

A wireless handheld probe with spectrally constrained evolution strategies for diffuse optical imaging of tissue

NASA Astrophysics Data System (ADS)

Flexman, M. L.; Kim, H. K.; Stoll, R.; Khalil, M. A.; Fong, C. J.; Hielscher, A. H.

2012-03-01

We present a low-cost, portable, wireless diffuse optical imaging device. The handheld device is fast, portable, and can be applied to a wide range of both static and dynamic imaging applications including breast cancer, functional brain imaging, and peripheral artery disease. The continuous-wave probe has four near-infrared wavelengths and uses digital detection techniques to perform measurements at 2.3 Hz. Using a multispectral evolution algorithm for chromophore reconstruction, we can measure absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Performance of the device is demonstrated using a series of liquid phantoms comprised of Intralipid®, ink, and dye.

Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study.

PubMed

Fu, Cynthia H Y; Williams, Steven C R; Cleare, Anthony J; Brammer, Michael J; Walsh, Nicholas D; Kim, Jieun; Andrew, Chris M; Pich, Emilio Merlo; Williams, Pauline M; Reed, Laurence J; Mitterschiffthaler, Martina T; Suckling, John; Bullmore, Edward T

2004-09-01

Depression is associated with interpersonal difficulties related to abnormalities in affective facial processing. To map brain systems activated by sad facial affect processing in patients with depression and to identify brain functional correlates of antidepressant treatment and symptomatic response. Two groups underwent scanning twice using functional magnetic resonance imaging (fMRI) during an 8-week period. The event-related fMRI paradigm entailed incidental affect recognition of facial stimuli morphed to express discriminable intensities of sadness. Participants were recruited by advertisement from the local population; depressed subjects were treated as outpatients. We matched 19 medication-free, acutely symptomatic patients satisfying DSM-IV criteria for unipolar major depressive disorder by age, sex, and IQ with 19 healthy volunteers. Intervention After the baseline assessment, patients received fluoxetine hydrochloride, 20 mg/d, for 8 weeks. Average activation (capacity) and differential response to variable affective intensity (dynamic range) were estimated in each fMRI time series. We used analysis of variance to identify brain regions that demonstrated a main effect of group (depressed vs healthy subjects) and a group x time interaction (attributable to antidepressant treatment). Change in brain activation associated with reduction of depressive symptoms in the patient group was identified by means of regression analysis. Permutation tests were used for inference. Over time, depressed subjects showed reduced capacity for activation in the left amygdala, ventral striatum, and frontoparietal cortex and a negatively correlated increase of dynamic range in the prefrontal cortex. Symptomatic improvement was associated with reduction of dynamic range in the pregenual cingulate cortex, ventral striatum, and cerebellum. Antidepressant treatment reduces left limbic, subcortical, and neocortical capacity for activation in depressed subjects and increases the dynamic range of the left prefrontal cortex. Changes in anterior cingulate function associated with symptomatic improvement indicate that fMRI may be a useful surrogate marker of antidepressant treatment response.

Rapid anatomical brain imaging using spiral acquisition and an expanded signal model.

PubMed

Kasper, Lars; Engel, Maria; Barmet, Christoph; Haeberlin, Maximilian; Wilm, Bertram J; Dietrich, Benjamin E; Schmid, Thomas; Gross, Simon; Brunner, David O; Stephan, Klaas E; Pruessmann, Klaas P

2018-03-01

We report the deployment of spiral acquisition for high-resolution structural imaging at 7T. Long spiral readouts are rendered manageable by an expanded signal model including static off-resonance and B 0 dynamics along with k-space trajectories and coil sensitivity maps. Image reconstruction is accomplished by inversion of the signal model using an extension of the iterative non-Cartesian SENSE algorithm. Spiral readouts up to 25 ms are shown to permit whole-brain 2D imaging at 0.5 mm in-plane resolution in less than a minute. A range of options is explored, including proton-density and T 2 * contrast, acceleration by parallel imaging, different readout orientations, and the extraction of phase images. Results are shown to exhibit competitive image quality along with high geometric consistency. Copyright © 2017 Elsevier Inc. All rights reserved.

Image quality prediction - An aid to the Viking lander imaging investigation on Mars

NASA Technical Reports Server (NTRS)

Huck, F. O.; Wall, S. D.

1976-01-01

Image quality criteria and image quality predictions are formulated for the multispectral panoramic cameras carried by the Viking Mars landers. Image quality predictions are based on expected camera performance, Mars surface radiance, and lighting and viewing geometry (fields of view, Mars lander shadows, solar day-night alternation), and are needed in diagnosis of camera performance, in arriving at a preflight imaging strategy, and revision of that strategy should the need arise. Landing considerations, camera control instructions, camera control logic, aspects of the imaging process (spectral response, spatial response, sensitivity), and likely problems are discussed. Major concerns include: degradation of camera response by isotope radiation, uncertainties in lighting and viewing geometry and in landing site local topography, contamination of camera window by dust abrasion, and initial errors in assigning camera dynamic ranges (gains and offsets).

Integrated Dual Imaging Detector

NASA Technical Reports Server (NTRS)

Rust, David M.

1999-01-01

A new type of image detector was designed to simultaneously analyze the polarization of light at all picture elements in a scene. The integrated Dual Imaging detector (IDID) consists of a lenslet array and a polarizing beamsplitter bonded to a commercial charge coupled device (CCD). The IDID simplifies the design and operation of solar vector magnetographs and the imaging polarimeters and spectroscopic imagers used, for example, in atmosphere and solar research. When used in a solar telescope, the vector magnetic fields on the solar surface. Other applications include environmental monitoring, robot vision, and medical diagnoses (through the eye). Innovations in the IDID include (1) two interleaved imaging arrays (one for each polarization plane); (2) large dynamic range (well depth of 10(exp 5) electrons per pixel); (3) simultaneous readout and display of both images; and (4) laptop computer signal processing to produce polarization maps in field situations.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilke, R. N., E-mail: rwilke@gwdg.de; Wallentin, J.; Osterhoff, M.

The Large Area Medipix-Based Detector Array (Lambda) has been used in a ptychographic imaging experiment on solar-cell nanowires. By using a semi-transparent central stop, the high flux density provided by nano-focusing Kirkpatrick–Baez mirrors can be fully exploited for high-resolution phase reconstructions. Suitable detection systems that are capable of recording high photon count rates with single-photon detection are instrumental for coherent X-ray imaging. The new single-photon-counting pixel detector ‘Lambda’ has been tested in a ptychographic imaging experiment on solar-cell nanowires using Kirkpatrick–Baez-focused 13.8 keV X-rays. Taking advantage of the high count rate of the Lambda and dynamic range expansion by themore » semi-transparent central stop, a high-dynamic-range diffraction signal covering more than seven orders of magnitude has been recorded, which corresponds to a photon flux density of about 10{sup 5} photons nm{sup −2} s{sup −1} or a flux of ∼10{sup 10} photons s{sup −1} on the sample. By comparison with data taken without the semi-transparent central stop, an increase in resolution by a factor of 3–4 is determined: from about 125 nm to about 38 nm for the nanowire and from about 83 nm to about 21 nm for the illuminating wavefield.« less

A design of optical modulation system with pixel-level modulation accuracy

NASA Astrophysics Data System (ADS)

Zheng, Shiwei; Qu, Xinghua; Feng, Wei; Liang, Baoqiu

2018-01-01

Vision measurement has been widely used in the field of dimensional measurement and surface metrology. However, traditional methods of vision measurement have many limits such as low dynamic range and poor reconfigurability. The optical modulation system before image formation has the advantage of high dynamic range, high accuracy and more flexibility, and the modulation accuracy is the key parameter which determines the accuracy and effectiveness of optical modulation system. In this paper, an optical modulation system with pixel level accuracy is designed and built based on multi-points reflective imaging theory and digital micromirror device (DMD). The system consisted of digital micromirror device, CCD camera and lens. Firstly we achieved accurate pixel-to-pixel correspondence between the DMD mirrors and the CCD pixels by moire fringe and an image processing of sampling and interpolation. Then we built three coordinate systems and calculated the mathematic relationship between the coordinate of digital micro-mirror and CCD pixels using a checkerboard pattern. A verification experiment proves that the correspondence error is less than 0.5 pixel. The results show that the modulation accuracy of system meets the requirements of modulation. Furthermore, the high reflecting edge of a metal circular piece can be detected using the system, which proves the effectiveness of the optical modulation system.

A high-throughput AO/PI-based cell concentration and viability detection method using the Celigo image cytometry.

PubMed

Chan, Leo Li-Ying; Smith, Tim; Kumph, Kendra A; Kuksin, Dmitry; Kessel, Sarah; Déry, Olivier; Cribbes, Scott; Lai, Ning; Qiu, Jean

2016-10-01

To ensure cell-based assays are performed properly, both cell concentration and viability have to be determined so that the data can be normalized to generate meaningful and comparable results. Cell-based assays performed in immuno-oncology, toxicology, or bioprocessing research often require measuring of multiple samples and conditions, thus the current automated cell counter that uses single disposable counting slides is not practical for high-throughput screening assays. In the recent years, a plate-based image cytometry system has been developed for high-throughput biomolecular screening assays. In this work, we demonstrate a high-throughput AO/PI-based cell concentration and viability method using the Celigo image cytometer. First, we validate the method by comparing directly to Cellometer automated cell counter. Next, cell concentration dynamic range, viability dynamic range, and consistency are determined. The high-throughput AO/PI method described here allows for 96-well to 384-well plate samples to be analyzed in less than 7 min, which greatly reduces the time required for the single sample-based automated cell counter. In addition, this method can improve the efficiency for high-throughput screening assays, where multiple cell counts and viability measurements are needed prior to performing assays such as flow cytometry, ELISA, or simply plating cells for cell culture.

How much image noise can be added in cardiac x-ray imaging without loss in perceived image quality?

NASA Astrophysics Data System (ADS)

Gislason-Lee, Amber J.; Kumcu, Asli; Kengyelics, Stephen M.; Rhodes, Laura A.; Davies, Andrew G.

2015-03-01

Dynamic X-ray imaging systems are used for interventional cardiac procedures to treat coronary heart disease. X-ray settings are controlled automatically by specially-designed X-ray dose control mechanisms whose role is to ensure an adequate level of image quality is maintained with an acceptable radiation dose to the patient. Current commonplace dose control designs quantify image quality by performing a simple technical measurement directly from the image. However, the utility of cardiac X-ray images is in their interpretation by a cardiologist during an interventional procedure, rather than in a technical measurement. With the long term goal of devising a clinically-relevant image quality metric for an intelligent dose control system, we aim to investigate the relationship of image noise with clinical professionals' perception of dynamic image sequences. Computer-generated noise was added, in incremental amounts, to angiograms of five different patients selected to represent the range of adult cardiac patient sizes. A two alternative forced choice staircase experiment was used to determine the amount of noise which can be added to a patient image sequences without changing image quality as perceived by clinical professionals. Twenty-five viewing sessions (five for each patient) were completed by thirteen observers. Results demonstrated scope to increase the noise of cardiac X-ray images by up to 21% +/- 8% before it is noticeable by clinical professionals. This indicates a potential for 21% radiation dose reduction since X-ray image noise and radiation dose are directly related; this would be beneficial to both patients and personnel.

Imaging of laboratory magnetospheric plasmas using coherence imaging technique

NASA Astrophysics Data System (ADS)

Nishiura, Masaki; Takahashi, Noriki; Yoshida, Zensho; Nakamura, Kaori; Kawazura, Yohei; Kenmochi, Naoki; Nakatsuka, Masataka; Sugata, Tetsuya; Katsura, Shotaro; Howard, John

2017-10-01

The ring trap 1 (RT-1) device creates a laboratory magnetosphere for the studies on plasma physics and advanced nuclear fusion. A levitated superconducting coil produces magnetic dipole fields that realize a high beta plasma confinement that is motivated by self-organized plasmas in planetary magnetospheres. The electron cyclotron resonance heating (ECRH) with 8.2 GHz and 50 kW produces the plasmas with hot electrons in a few ten keV range. The electrons contribute to the local electron beta that exceeded 1 in RT-1. For the ion heating, ion cyclotron range of frequencies (ICRF) heating with 2-4 MHz and 10 kW has been performed in RT-1. The radial profile of ion temperature by a spectroscopic measurement indicates the signature of ion heating. In the holistic point of view, a coherence imaging system has been implemented for imaging the entire ion dynamics in the laboratory magnetosphere. The diagnostic system and obtained results will be presented.

Measurements of spatially resolved velocity variations in shock compressed heterogeneous materials using a line-imaging velocity interferometer

NASA Astrophysics Data System (ADS)

Trott, Wayne M.; Knudson, Marcus D.; Chhabildas, Lalit C.; Asay, James R.

2000-04-01

Relatively straightforward changes in the design of a conventional optically recording velocity interferometer system (ORVIS) can be used to produce a line-imaging instrument that allows adjustment of spatial resolution over a wide range. As a result, line-imaging ORVIS can be tailored to various specific applications involving dynamic deformation of heterogeneous materials as required by their characteristic length scales (ranging from a few μm for ferroelectric ceramics to a few mm for concrete). A line-imaging system has been successfully interfaced to a compressed gas gun driver and fielded on numerous tests in combination with simultaneous dual delay-leg, "push-pull" VISAR measurements. These tests include shock loading of glass-reinforced polyester composites, foam reverberation experiments (measurements at the free surface of a thin aluminum plate impacted by foam), and measurements of dispersive velocity in a shock-loaded explosive simulant (sugar). Results are presented that illustrate the capability for recording detailed spatially resolved material response.

Landsat-8 Operational Land Imager (OLI) radiometric performance on-orbit

USGS Publications Warehouse

Morfitt, Ron; Barsi, Julia A.; Levy, Raviv; Markham, Brian L.; Micijevic, Esad; Ong, Lawrence; Scaramuzza, Pat; Vanderwerff, Kelly

2015-01-01

Expectations of the Operational Land Imager (OLI) radiometric performance onboard Landsat-8 have been met or exceeded. The calibration activities that occurred prior to launch provided calibration parameters that enabled ground processing to produce imagery that met most requirements when data were transmitted to the ground. Since launch, calibration updates have improved the image quality even more, so that all requirements are met. These updates range from detector gain coefficients to reduce striping and banding to alignment parameters to improve the geometric accuracy. This paper concentrates on the on-orbit radiometric performance of the OLI, excepting the radiometric calibration performance. Topics discussed in this paper include: signal-to-noise ratios that are an order of magnitude higher than previous Landsat missions; radiometric uniformity that shows little residual banding and striping, and continues to improve; a dynamic range that limits saturation to extremely high radiance levels; extremely stable detectors; slight nonlinearity that is corrected in ground processing; detectors that are stable and 100% operable; and few image artifacts.

Jupiter cloud morphology and zonal winds from ground-based observations before and during Juno exploration

NASA Astrophysics Data System (ADS)

Sanchez-Lavega, A.; Hueso, R.; Perez-Hoyos, S.; Iñurrigarro, P.; Mendikoa, I.; Rojas, J. F.

2016-12-01

We present the results of a long term campaign between September 2015 and August 2016 of imaging of Jupiter's cloud morphology and zonal winds in the 0.38 - 1.7 μm wavelength spectral range. We use PlanetCam lucky imaging camera at the 2.2m telescope at Calar Alto Observatory in Spain, and for the optical range, the contribution of a network of observers to the Planetary Virtual Observatory Laboratory database (PVOL-IOPW at http://pvol.ehu.eus). We have complemented the study with Hubble Space Telescope WFC3 camera images taken in the 0.275 - 0.89 μm wavelength spectral range during the OPAL program on 9 February 2016. The PlanetCam images have been calibrated in radiance using spectrophotometric standard stars providing absolute reflectivity across the disk in a large series of broadband and narrowband filters sensitive to the altitude distribution and size of aerosols above the ammonia cloud level, and to the spectral dependence of the chromophore coloring agents. The cloud morphology evolution has been studied with an horizontal resolution ranging from 150 to 1000 km. Zonal wind profiles have been retrieved along the whole observing period from tracking cloud motions that span the latitude range from -80° to +77º. Combining all these results we characterized the 3D-dynamical state and cloud and haze distribution in Jupiter's atmosphere in the altitude range between 10 mbar and 1.5 bar before and during Juno initial exploration.

The PixFEL project: Progress towards a fine pitch X-ray imaging camera for next generation FEL facilities

NASA Astrophysics Data System (ADS)

Rizzo, G.; Batignani, G.; Benkechkache, M. A.; Bettarini, S.; Casarosa, G.; Comotti, D.; Dalla Betta, G.-F.; Fabris, L.; Forti, F.; Grassi, M.; Lodola, L.; Malcovati, P.; Manghisoni, M.; Mendicino, R.; Morsani, F.; Paladino, A.; Pancheri, L.; Paoloni, E.; Ratti, L.; Re, V.; Traversi, G.; Vacchi, C.; Verzellesi, G.; Xu, H.

2016-07-01

The INFN PixFEL project is developing the fundamental building blocks for a large area X-ray imaging camera to be deployed at next generation free electron laser (FEL) facilities with unprecedented intensity. Improvement in performance beyond the state of art in imaging instrumentation will be explored adopting advanced technologies like active edge sensors, a 65 nm node CMOS process and vertical integration. These are the key ingredients of the PixFEL project to realize a seamless large area focal plane instrument composed by a matrix of multilayer four-side buttable tiles. In order to minimize the dead area and reduce ambiguities in image reconstruction, a fine pitch active edge thick sensor is being optimized to cope with very high intensity photon flux, up to 104 photons per pixel, in the range from 1 to 10 keV. A low noise analog front-end channel with this wide dynamic range and a novel dynamic compression feature, together with a low power 10 bit analog to digital conversion up to 5 MHz, has been realized in a 110 μm pitch with a 65 nm CMOS process. Vertical interconnection of two CMOS tiers will be also explored in the future to build a four-side buttable readout chip with high density memories. In the long run the objective of the PixFEL project is to build a flexible X-ray imaging camera for operation both in burst mode, like at the European X-FEL, or in continuous mode with the high frame rates anticipated for future FEL facilities.

Multiple-Event, Single-Photon Counting Imaging Sensor

NASA Technical Reports Server (NTRS)

Zheng, Xinyu; Cunningham, Thomas J.; Sun, Chao; Wang, Kang L.

2011-01-01

The single-photon counting imaging sensor is typically an array of silicon Geiger-mode avalanche photodiodes that are monolithically integrated with CMOS (complementary metal oxide semiconductor) readout, signal processing, and addressing circuits located in each pixel and the peripheral area of the chip. The major problem is its single-event method for photon count number registration. A single-event single-photon counting imaging array only allows registration of up to one photon count in each of its pixels during a frame time, i.e., the interval between two successive pixel reset operations. Since the frame time can t be too short, this will lead to very low dynamic range and make the sensor merely useful for very low flux environments. The second problem of the prior technique is a limited fill factor resulting from consumption of chip area by the monolithically integrated CMOS readout in pixels. The resulting low photon collection efficiency will substantially ruin any benefit gained from the very sensitive single-photon counting detection. The single-photon counting imaging sensor developed in this work has a novel multiple-event architecture, which allows each of its pixels to register as more than one million (or more) photon-counting events during a frame time. Because of a consequently boosted dynamic range, the imaging array of the invention is capable of performing single-photon counting under ultra-low light through high-flux environments. On the other hand, since the multiple-event architecture is implemented in a hybrid structure, back-illumination and close-to-unity fill factor can be realized, and maximized quantum efficiency can also be achieved in the detector array.

Statistical characterization of speckle noise in coherent imaging systems

NASA Astrophysics Data System (ADS)

Yaroslavsky, Leonid; Shefler, A.

2003-05-01

Speckle noise imposes fundamental limitation on image quality in coherent radiation based imaging and optical metrology systems. Speckle noise phenomena are associated with properties of objects to diffusely scatter irradiation and with the fact that in recording the wave field, a number of signal distortions inevitably occur due to technical limitations inherent to hologram sensors. The statistical theory of speckle noise was developed with regard to only limited resolving power of coherent imaging devices. It is valid only asymptotically as much as the central limit theorem of the probability theory can be applied. In applications this assumption is not always applicable. Moreover, in treating speckle noise problem one should also consider other sources of the hologram deterioration. In the paper, statistical properties of speckle due to the limitation of hologram size, dynamic range and hologram signal quantization are studied by Monte-Carlo simulation for holograms recorded in near and far diffraction zones. The simulation experiments have shown that, for limited resolving power of the imaging system, widely accepted opinion that speckle contrast is equal to one holds only for rather severe level of the hologram size limitation. For moderate limitations, speckle contrast changes gradually from zero for no limitation to one for limitation to less than about 20% of hologram size. The results obtained for the limitation of the hologram sensor"s dynamic range and hologram signal quantization reveal that speckle noise due to these hologram signal distortions is not multiplicative and is directly associated with the severity of the limitation and quantization. On the base of the simulation results, analytical models are suggested.

Wide-field surface plasmon microscopy of nano- and microparticles: features, benchmarking, limitations, and bioanalytical applications

NASA Astrophysics Data System (ADS)

Nizamov, Shavkat; Scherbahn, Vitali; Mirsky, Vladimir M.

2017-05-01

Detection of nano- and micro-particles is an important task for chemical analytics, food industry, biotechnology, environmental monitoring and many other fields of science and industry. For this purpose, a method based on the detection and analysis of minute signals in surface plasmon resonance images due to adsorption of single nanopartciles was developed. This new technology allows one a real-time detection of interaction of single nano- and micro-particles with sensor surface. Adsorption of each nanoparticle leads to characteristic diffraction image whose intensity depends on the size and chemical composition of the particle. The adsorption rate characterizes volume concentration of nano- and micro-particles. Large monitored surface area of sensor enables a high dynamic range of counting and to a correspondingly high dynamic range in concentration scale. Depending on the type of particles and experimental conditions, the detection limit for aqueous samples can be below 1000 particles per microliter. For application of method in complex media, nanoparticle images are discriminated from image perturbations due to matrix components. First, the characteristic SPRM images of nanoparticles (templates) are collected in aqueous suspensions or spiked real samples. Then, the detection of nanoparticles in complex media using template matching is performed. The detection of various NPs in consumer products like cosmetics, mineral water, juices, and wines was shown at sub-ppb level. The method can be applied for ultrasensitive detection and analysis of nano- and micro-particles of biological (bacteria, viruses, endosomes), biotechnological (liposomes, protein nanoparticles for drug delivery) or technical origin.

Overcoming Dynamic Disturbances in Imaging Systems

NASA Technical Reports Server (NTRS)

Young, Eric W.; Dente, Gregory C.; Lyon, Richard G.; Chesters, Dennis; Gong, Qian

2000-01-01

We develop and discuss a methodology with the potential to yield a significant reduction in complexity, cost, and risk of space-borne optical systems in the presence of dynamic disturbances. More robust systems almost certainly will be a result as well. Many future space-based and ground-based optical systems will employ optical control systems to enhance imaging performance. The goal of the optical control subsystem is to determine the wavefront aberrations and remove them. Ideally reducing an aberrated image of the object under investigation to a sufficiently clear (usually diffraction-limited) image. Control will likely be distributed over several elements. These elements may include telescope primary segments, telescope secondary, telescope tertiary, deformable mirror(s), fine steering mirror(s), etc. The last two elements, in particular, may have to provide dynamic control. These control subsystems may become elaborate indeed. But robust system performance will require evaluation of the image quality over a substantial range and in a dynamic environment. Candidate systems for improvement in the Earth Sciences Enterprise could include next generation Landsat systems or atmospheric sensors for dynamic imaging of individual, severe storms. The technology developed here could have a substantial impact on the development of new systems in the Space Science Enterprise; such as the Next Generation Space Telescope(NGST) and its follow-on the Next NGST. Large Interferometric Systems of non-zero field, such as Planet Finder and Submillimeter Probe of the Evolution of Cosmic Structure, could benefit. These systems most likely will contain large, flexible optomechanical structures subject to dynamic disturbance. Furthermore, large systems for high resolution imaging of planets or the sun from space may also benefit. Tactical and Strategic Defense systems will need to image very small targets as well and could benefit from the technology developed here. We discuss a novel speckle imaging technique with the potential to separate dynamic aberrations from static aberrations. Post-processing of a set of image data, using an algorithm based on this technique, should work for all but the lowest light levels and highest frequency dynamic environments. This technique may serve to reduce the complexity of the control system and provide for robust, fault-tolerant, reduced risk operation. For a given object, a short exposure image is "frozen" on the focal plane in the presence of the environmental disturbance (turbulence, jitter, etc.). A key factor is that this imaging data exhibits frame-to-frame linear shift invariance. Therefore, although the Point Spread Function is varying from frame to frame, the source is fixed; and each short exposure contains object spectrum data out to the diffraction limit of the imaging system. This novel speckle imaging technique uses the Knox-Thompson method. The magnitude of the complex object spectrum is straightforward to determine by well-established approaches. The phase of the complex object spectrum is decomposed into two parts. One is a single-valued function determined by the divergence of the optical phase gradient. The other is a multi-valued function determined by the circulation of the optical phase gradient-"hidden phase." Finite difference equations are developed for the phase. The novelty of this approach is captured in the inclusion of this "hidden phase." This technique allows the diffraction-limited reconstruction of the object from the ensemble of short exposure frames while simultaneously estimating the phase as a function of time from a set of exposures.

Overcoming Dynamic Disturbances in Imaging Systems

NASA Technical Reports Server (NTRS)

Young, Eric W.; Dente, Gregory C.; Lyon, Richard G.; Chesters, Dennis; Gong, Qian

2000-01-01

We develop and discuss a methodology with the potential to yield a significant reduction in complexity, cost, and risk of space-borne optical systems in the presence of dynamic disturbances. More robust systems almost certainly will be a result as well. Many future space-based and ground-based optical systems will employ optical control systems to enhance imaging performance. The goal of the optical control subsystem is to determine the wavefront aberrations and remove them. Ideally reducing an aberrated image of the object under investigation to a sufficiently clear (usually diffraction-limited) image. Control will likely be distributed over several elements. These elements may include telescope primary segments, telescope secondary, telescope tertiary, deformable mirror(s), fine steering mirror(s), etc. The last two elements, in particular, may have to provide dynamic control. These control subsystems may become elaborate indeed. But robust system performance will require evaluation of the image quality over a substantial range and in a dynamic environment. Candidate systems for improvement in the Earth Sciences Enterprise could include next generation Landsat systems or atmospheric sensors for dynamic imaging of individual, severe storms. The technology developed here could have a substantial impact on the development of new systems in the Space Science Enterprise; such as the Next Generation Space Telescope(NGST) and its follow-on the Next NGST. Large Interferometric Systems of non-zero field, such as Planet Finder and Submillimeter Probe of the Evolution of Cosmic Structure, could benefit. These systems most likely will contain large, flexible optormechanical structures subject to dynamic disturbance. Furthermore, large systems for high resolution imaging of planets or the sun from space may also benefit. Tactical and Strategic Defense systems will need to image very small targets as well and could benefit from the technology developed here. We discuss a novel speckle imaging technique with the potential to separate dynamic aberrations from static aberrations. Post-processing of a set of image data, using an algorithm based on this technique, should work for all but the lowest light levels and highest frequency dynamic environments. This technique may serve to reduce the complexity of the control system and provide for robust, fault-tolerant, reduced risk operation. For a given object, a short exposure image is "frozen" on the focal plane in the presence of the environmental disturbance (turbulence, jitter, etc.). A key factor is that this imaging data exhibits frame-to-frame linear shift invariance. Therefore, although the Point Spread Function is varying from frame to frame, the source is fixed; and each short exposure contains object spectrum data out to the diffraction limit of the imaging system. This novel speckle imaging technique uses the Knox-Thompson method. The magnitude of the complex object spectrum is straightforward to determine by well-established approaches. The phase of the complex object spectrum is decomposed into two parts. One is a single-valued function determined by the divergence of the optical phase gradient. The other is a multi-valued function determined by, the circulation of the optical phase gradient-"hidden phase." Finite difference equations are developed for the phase. The novelty of this approach is captured in the inclusion of this "hidden phase." This technique allows the diffraction-limited reconstruction of the object from the ensemble of short exposure frames while simultaneously estimating the phase as a function of time from a set of exposures.

Visualizing long-term single-molecule dynamics in vivo by stochastic protein labeling.

PubMed

Liu, Hui; Dong, Peng; Ioannou, Maria S; Li, Li; Shea, Jamien; Pasolli, H Amalia; Grimm, Jonathan B; Rivlin, Patricia K; Lavis, Luke D; Koyama, Minoru; Liu, Zhe

2018-01-09

Our ability to unambiguously image and track individual molecules in live cells is limited by packing of multiple copies of labeled molecules within the resolution limit. Here we devise a universal genetic strategy to precisely control copy number of fluorescently labeled molecules in a cell. This system has a dynamic range of ∼10,000-fold, enabling sparse labeling of proteins expressed at different abundance levels. Combined with photostable labels, this system extends the duration of automated single-molecule tracking by two orders of magnitude. We demonstrate long-term imaging of synaptic vesicle dynamics in cultured neurons as well as in intact zebrafish. We found axon initial segment utilizes a "waterfall" mechanism gating synaptic vesicle transport polarity by promoting anterograde transport processivity. Long-time observation also reveals that transcription factor hops between clustered binding sites in spatially restricted subnuclear regions, suggesting that topological structures in the nucleus shape local gene activities by a sequestering mechanism. This strategy thus greatly expands the spatiotemporal length scales of live-cell single-molecule measurements, enabling new experiments to quantitatively understand complex control of molecular dynamics in vivo.

Local/non-local regularized image segmentation using graph-cuts: application to dynamic and multispectral MRI.

PubMed

Hanson, Erik A; Lundervold, Arvid

2013-11-01

Multispectral, multichannel, or time series image segmentation is important for image analysis in a wide range of applications. Regularization of the segmentation is commonly performed using local image information causing the segmented image to be locally smooth or piecewise constant. A new spatial regularization method, incorporating non-local information, was developed and tested. Our spatial regularization method applies to feature space classification in multichannel images such as color images and MR image sequences. The spatial regularization involves local edge properties, region boundary minimization, as well as non-local similarities. The method is implemented in a discrete graph-cut setting allowing fast computations. The method was tested on multidimensional MRI recordings from human kidney and brain in addition to simulated MRI volumes. The proposed method successfully segment regions with both smooth and complex non-smooth shapes with a minimum of user interaction.

FIRST IMAGES FROM THE FOCUSING OPTICS X-RAY SOLAR IMAGER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krucker, Säm; Glesener, Lindsay; Turin, Paul

2014-10-01

The Focusing Optics X-ray Solar Imager (FOXSI) sounding rocket payload flew for the first time on 2012 November 2, producing the first focused images of the Sun above 5 keV. To enable hard X-ray (HXR) imaging spectroscopy via direct focusing, FOXSI makes use of grazing-incidence replicated optics combined with fine-pitch solid-state detectors. On its first flight, FOXSI observed several targets that included active regions, the quiet Sun, and a GOES-class B2.7 microflare. This Letter provides an introduction to the FOXSI instrument and presents its first solar image. These data demonstrate the superiority in sensitivity and dynamic range that is achievable with amore » direct HXR imager with respect to previous, indirect imaging methods, and illustrate the technological readiness for a spaceborne mission to observe HXRs from solar flares via direct focusing optics.« less

Light field imaging and application analysis in THz

NASA Astrophysics Data System (ADS)

Zhang, Hongfei; Su, Bo; He, Jingsuo; Zhang, Cong; Wu, Yaxiong; Zhang, Shengbo; Zhang, Cunlin

2018-01-01

The light field includes the direction information and location information. Light field imaging can capture the whole light field by single exposure. The four-dimensional light field function model represented by two-plane parameter, which is proposed by Levoy, is adopted in the light field. Acquisition of light field is based on the microlens array, camera array and the mask. We calculate the dates of light-field to synthetize light field image. The processing techniques of light field data include technology of refocusing rendering, technology of synthetic aperture and technology of microscopic imaging. Introducing the technology of light field imaging into THz, the efficiency of 3D imaging is higher than that of conventional THz 3D imaging technology. The advantages compared with visible light field imaging include large depth of field, wide dynamic range and true three-dimensional. It has broad application prospects.

Design and testing of a dual-band enhanced vision system

NASA Astrophysics Data System (ADS)

Way, Scott P.; Kerr, Richard; Imamura, Joseph J.; Arnoldy, Dan; Zeylmaker, Dick; Zuro, Greg

2003-09-01

An effective enhanced vision system must operate over a broad spectral range in order to offer a pilot an optimized scene that includes runway background as well as airport lighting and aircraft operations. The large dynamic range of intensities of these images is best handled with separate imaging sensors. The EVS 2000 is a patented dual-band Infrared Enhanced Vision System (EVS) utilizing image fusion concepts. It has the ability to provide a single image from uncooled infrared imagers combined with SWIR, NIR or LLLTV sensors. The system is designed to provide commercial and corporate airline pilots with improved situational awareness at night and in degraded weather conditions but can also be used in a variety of applications where the fusion of dual band or multiband imagery is required. A prototype of this system was recently fabricated and flown on the Boeing Advanced Technology Demonstrator 737-900 aircraft. This paper will discuss the current EVS 2000 concept, show results taken from the Boeing Advanced Technology Demonstrator program, and discuss future plans for the fusion system.

Report on recent results of the PERCIVAL soft X-ray imager

NASA Astrophysics Data System (ADS)

Khromova, A.; Cautero, G.; Giuressi, D.; Menk, R.; Pinaroli, G.; Stebel, L.; Correa, J.; Marras, A.; Wunderer, C. B.; Lange, S.; Tennert, M.; Niemann, M.; Hirsemann, H.; Smoljanin, S.; Reza, S.; Graafsma, H.; Göttlicher, P.; Shevyakov, I.; Supra, J.; Xia, Q.; Zimmer, M.; Guerrini, N.; Marsh, B.; Sedgwick, I.; Nicholls, T.; Turchetta, R.; Pedersen, U.; Tartoni, N.; Hyun, H. J.; Kim, K. S.; Rah, S. Y.; Hoenk, M. E.; Jewell, A. D.; Jones, T. J.; Nikzad, S.

2016-11-01

The PERCIVAL (Pixelated Energy Resolving CMOS Imager, Versatile And Large) soft X-ray 2D imaging detector is based on stitched, wafer-scale sensors possessing a thick epi-layer, which together with back-thinning and back-side illumination yields elevated quantum efficiency in the photon energy range of 125-1000 eV. Main application fields of PERCIVAL are foreseen in photon science with FELs and synchrotron radiation. This requires high dynamic range up to 105 ph @ 250 eV paired with single photon sensitivity with high confidence at moderate frame rates in the range of 10-120 Hz. These figures imply the availability of dynamic gain switching on a pixel-by-pixel basis and a highly parallel, low noise analog and digital readout, which has been realized in the PERCIVAL sensor layout. Different aspects of the detector performance have been assessed using prototype sensors with different pixel and ADC types. This work will report on the recent test results performed on the newest chip prototypes with the improved pixel and ADC architecture. For the target frame rates in the 10-120 Hz range an average noise floor of 14e- has been determined, indicating the ability of detecting single photons with energies above 250 eV. Owing to the successfully implemented adaptive 3-stage multiple-gain switching, the integrated charge level exceeds 4 · 106 e- or 57000 X-ray photons at 250 eV per frame at 120 Hz. For all gains the noise level remains below the Poisson limit also in high-flux conditions. Additionally, a short overview over the updates on an oncoming 2 Mpixel (P2M) detector system (expected at the end of 2016) will be reported.

Snapshot Serengeti, high-frequency annotated camera trap images of 40 mammalian species in an African savanna

PubMed Central

Swanson, Alexandra; Kosmala, Margaret; Lintott, Chris; Simpson, Robert; Smith, Arfon; Packer, Craig

2015-01-01

Camera traps can be used to address large-scale questions in community ecology by providing systematic data on an array of wide-ranging species. We deployed 225 camera traps across 1,125 km2 in Serengeti National Park, Tanzania, to evaluate spatial and temporal inter-species dynamics. The cameras have operated continuously since 2010 and had accumulated 99,241 camera-trap days and produced 1.2 million sets of pictures by 2013. Members of the general public classified the images via the citizen-science website www.snapshotserengeti.org. Multiple users viewed each image and recorded the species, number of individuals, associated behaviours, and presence of young. Over 28,000 registered users contributed 10.8 million classifications. We applied a simple algorithm to aggregate these individual classifications into a final ‘consensus’ dataset, yielding a final classification for each image and a measure of agreement among individual answers. The consensus classifications and raw imagery provide an unparalleled opportunity to investigate multi-species dynamics in an intact ecosystem and a valuable resource for machine-learning and computer-vision research. PMID:26097743

Proton beam spatial distribution and Bragg peak imaging by photoluminescence of color centers in lithium fluoride crystals at the TOP-IMPLART linear accelerator

NASA Astrophysics Data System (ADS)

Piccinini, M.; Ronsivalle, C.; Ampollini, A.; Bazzano, G.; Picardi, L.; Nenzi, P.; Trinca, E.; Vadrucci, M.; Bonfigli, F.; Nichelatti, E.; Vincenti, M. A.; Montereali, R. M.

2017-11-01

Solid-state radiation detectors based on the photoluminescence of stable point defects in lithium fluoride crystals have been used for advanced diagnostics during the commissioning of the segment up to 27 MeV of the TOP-IMPLART proton linear accelerator for proton therapy applications, under development at ENEA C.R. Frascati, Italy. The LiF detectors high intrinsic spatial resolution and wide dynamic range allow obtaining two-dimensional images of the beam transverse intensity distribution and also identifying the Bragg peak position with micrometric precision by using a conventional optical fluorescence microscope. Results of the proton beam characterization, among which, the estimation of beam energy components and dynamics, are reported and discussed for different operating conditions of the accelerator.

Effects of window size and shape on accuracy of subpixel centroid estimation of target images

NASA Technical Reports Server (NTRS)

Welch, Sharon S.

1993-01-01

A new algorithm is presented for increasing the accuracy of subpixel centroid estimation of (nearly) point target images in cases where the signal-to-noise ratio is low and the signal amplitude and shape vary from frame to frame. In the algorithm, the centroid is calculated over a data window that is matched in width to the image distribution. Fourier analysis is used to explain the dependency of the centroid estimate on the size of the data window, and simulation and experimental results are presented which demonstrate the effects of window size for two different noise models. The effects of window shape were also investigated for uniform and Gaussian-shaped windows. The new algorithm was developed to improve the dynamic range of a close-range photogrammetric tracking system that provides feedback for control of a large gap magnetic suspension system (LGMSS).

Perception of linear horizontal self-motion induced by peripheral vision /linearvection/ - Basic characteristics and visual-vestibular interactions

NASA Technical Reports Server (NTRS)

Berthoz, A.; Pavard, B.; Young, L. R.

1975-01-01

The basic characteristics of the sensation of linear horizontal motion have been studied. Objective linear motion was induced by means of a moving cart. Visually induced linear motion perception (linearvection) was obtained by projection of moving images at the periphery of the visual field. Image velocity and luminance thresholds for the appearance of linearvection have been measured and are in the range of those for image motion detection (without sensation of self motion) by the visual system. Latencies of onset are around 1 sec and short term adaptation has been shown. The dynamic range of the visual analyzer as judged by frequency analysis is lower than the vestibular analyzer. Conflicting situations in which visual cues contradict vestibular and other proprioceptive cues show, in the case of linearvection a dominance of vision which supports the idea of an essential although not independent role of vision in self motion perception.

Relaxometry imaging of superparamagnetic magnetite nanoparticles at ambient conditions

NASA Astrophysics Data System (ADS)

Finkler, Amit; Schmid-Lorch, Dominik; Häberle, Thomas; Reinhard, Friedemann; Zappe, Andrea; Slota, Michael; Bogani, Lapo; Wrachtrup, Jörg

We present a novel technique to image superparamagnetic iron oxide nanoparticles via their fluctuating magnetic fields. The detection is based on the nitrogen-vacancy (NV) color center in diamond, which allows optically detected magnetic resonance (ODMR) measurements on its electron spin structure. In combination with an atomic-force-microscope, this atomic-sized color center maps ambient magnetic fields in a wide frequency range from DC up to several GHz, while retaining a high spatial resolution in the sub-nanometer range. We demonstrate imaging of single 10 nm sized magnetite nanoparticles using this spin noise detection technique. By fitting simulations (Ornstein-Uhlenbeck process) to the data, we are able to infer additional information on such a particle and its dynamics, like the attempt frequency and the anisotropy constant. This is of high interest to the proposed application of magnetite nanoparticles as an alternative MRI contrast agent or to the field of particle-aided tumor hyperthermia.

Technical Competencies Applied in Experimental Fluid Dynamics

NASA Astrophysics Data System (ADS)

Tagg, Randall

2017-11-01

The practical design, construction, and operation of fluid dynamics experiments require a broad range of competencies. Three types are instrumental, procedural, and design. Respective examples would be operation of a spectrum analyzer, soft-soldering or brazing flow plumbing, and design of a small wind tunnel. Some competencies, such as the selection and installation of pumping systems, are unique to fluid dynamics and fluids engineering. Others, such as the design and construction of electronic amplifiers or optical imaging systems, overlap with other fields. Thus the identification and development of learning materials and methods for instruction are part of a larger effort to identify competencies needed in active research and technical innovation.

Magnetic Resonance Imaging (MRI): Dynamic Pelvic Floor

MedlinePlus

... Site Index A-Z Magnetic Resonance Imaging (MRI) – Dynamic Pelvic Floor Dynamic pelvic floor magnetic resonance imaging ( ... the limitations of pelvic floor MRI? What is dynamic pelvic floor MRI? Magnetic resonance imaging (MRI) is ...

High-speed particle tracking in microscopy using SPAD image sensors

NASA Astrophysics Data System (ADS)

Gyongy, Istvan; Davies, Amy; Miguelez Crespo, Allende; Green, Andrew; Dutton, Neale A. W.; Duncan, Rory R.; Rickman, Colin; Henderson, Robert K.; Dalgarno, Paul A.

2018-02-01

Single photon avalanche diodes (SPADs) are used in a wide range of applications, from fluorescence lifetime imaging microscopy (FLIM) to time-of-flight (ToF) 3D imaging. SPAD arrays are becoming increasingly established, combining the unique properties of SPADs with widefield camera configurations. Traditionally, the photosensitive area (fill factor) of SPAD arrays has been limited by the in-pixel digital electronics. However, recent designs have demonstrated that by replacing the complex digital pixel logic with simple binary pixels and external frame summation, the fill factor can be increased considerably. A significant advantage of such binary SPAD arrays is the high frame rates offered by the sensors (>100kFPS), which opens up new possibilities for capturing ultra-fast temporal dynamics in, for example, life science cellular imaging. In this work we consider the use of novel binary SPAD arrays in high-speed particle tracking in microscopy. We demonstrate the tracking of fluorescent microspheres undergoing Brownian motion, and in intra-cellular vesicle dynamics, at high frame rates. We thereby show how binary SPAD arrays can offer an important advance in live cell imaging in such fields as intercellular communication, cell trafficking and cell signaling.

Noninvasive assessment of the developing Xenopus cardiovascular system using optical coherence tomography

PubMed Central

Boppart, Stephen A.; Tearney, Gary J.; Bouma, Brett E.; Southern, James F.; Brezinski, Mark E.; Fujimoto, James G.

1997-01-01

Studies investigating normal and abnormal cardiac development are frequently limited by an inability to assess cardiovascular function within the intact organism. In this work, optical coherence tomography (OCT), a new method of micron-scale, noninvasive imaging based on the measurement of backscattered infrared light, was introduced for the high resolution assessment of structure and function in the developing Xenopus laevis cardiovascular system. Microstructural details, such as ventricular size and wall positions, were delineated with OCT at 16-μm resolution and correlated with histology. Three-dimensional representation of the cardiovascular system also was achieved by repeated cross-sectional imaging at intervals of 25 μm. In addition to structural information, OCT provides high speed in vivo axial ranging and imaging, allowing quantitative dynamic activity, such as ventricular ejection fraction, to be assessed. The sensitivity of OCT for dynamic assessment was demonstrated with an inotropic agent that altered cardiac function and dimensions. Optical coherence tomography is an attractive new technology for assessing cardiovascular development because of its high resolution, its ability to image through nontransparent structures, and its inexpensive portable design. In vivo and in vitro imaging are performed at a resolution approaching that of histopathology without the need for animal killing. PMID:9113976

Carotid lesion characterization by synthetic-aperture-imaging techniques with multioffset ultrasonic probes

NASA Astrophysics Data System (ADS)

Capineri, Lorenzo; Castellini, Guido; Masotti, Leonardo F.; Rocchi, Santina

1992-06-01

This paper explores the applications of a high-resolution imaging technique to vascular ultrasound diagnosis, with emphasis on investigation of the carotid vessel. With the present diagnostic systems, it is difficult to measure quantitatively the extension of the lesions and to characterize the tissue; quantitative images require enough spatial resolution and dynamic to reveal fine high-risk pathologies. A broadband synthetic aperture technique with multi-offset probes is developed to improve the lesion characterization by the evaluation of local scattering parameters. This technique works with weak scatterers embedded in a constant velocity medium, large aperture, and isotropic sources and receivers. The features of this technique are: axial and lateral spatial resolution of the order of the wavelength, high dynamic range, quantitative measurements of the size and scattering intensity of the inhomogeneities, and capabilities of investigation of inclined layer. The evaluation of the performances in real condition is carried out by a software simulator in which different experimental situations can be reproduced. Images of simulated anatomic test-objects are presented. The images are obtained with an inversion process of the synthesized ultrasonic signals, collected on the linear aperture by a limited number of finite size transducers.

Super-resolution depth information from a short-wave infrared laser gated-viewing system by using correlated double sampling

NASA Astrophysics Data System (ADS)

Göhler, Benjamin; Lutzmann, Peter

2017-10-01

Primarily, a laser gated-viewing (GV) system provides range-gated 2D images without any range resolution within the range gate. By combining two GV images with slightly different gate positions, 3D information within a part of the range gate can be obtained. The depth resolution is higher (super-resolution) than the minimal gate shift step size in a tomographic sequence of the scene. For a state-of-the-art system with a typical frame rate of 20 Hz, the time difference between the two required GV images is 50 ms which may be too long in a dynamic scenario with moving objects. Therefore, we have applied this approach to the reset and signal level images of a new short-wave infrared (SWIR) GV camera whose read-out integrated circuit supports correlated double sampling (CDS) actually intended for the reduction of kTC noise (reset noise). These images are extracted from only one single laser pulse with a marginal time difference in between. The SWIR GV camera consists of 640 x 512 avalanche photodiodes based on mercury cadmium telluride with a pixel pitch of 15 μm. A Q-switched, flash lamp pumped solid-state laser with 1.57 μm wavelength (OPO), 52 mJ pulse energy after beam shaping, 7 ns pulse length and 20 Hz pulse repetition frequency is used for flash illumination. In this paper, the experimental set-up is described and the operating principle of CDS is explained. The method of deriving super-resolution depth information from a GV system by using CDS is introduced and optimized. Further, the range accuracy is estimated from measured image data.

High Dynamic Range Pixel Array Detector for Scanning Transmission Electron Microscopy.

PubMed

Tate, Mark W; Purohit, Prafull; Chamberlain, Darol; Nguyen, Kayla X; Hovden, Robert; Chang, Celesta S; Deb, Pratiti; Turgut, Emrah; Heron, John T; Schlom, Darrell G; Ralph, Daniel C; Fuchs, Gregory D; Shanks, Katherine S; Philipp, Hugh T; Muller, David A; Gruner, Sol M

2016-02-01

We describe a hybrid pixel array detector (electron microscope pixel array detector, or EMPAD) adapted for use in electron microscope applications, especially as a universal detector for scanning transmission electron microscopy. The 128×128 pixel detector consists of a 500 µm thick silicon diode array bump-bonded pixel-by-pixel to an application-specific integrated circuit. The in-pixel circuitry provides a 1,000,000:1 dynamic range within a single frame, allowing the direct electron beam to be imaged while still maintaining single electron sensitivity. A 1.1 kHz framing rate enables rapid data collection and minimizes sample drift distortions while scanning. By capturing the entire unsaturated diffraction pattern in scanning mode, one can simultaneously capture bright field, dark field, and phase contrast information, as well as being able to analyze the full scattering distribution, allowing true center of mass imaging. The scattering is recorded on an absolute scale, so that information such as local sample thickness can be directly determined. This paper describes the detector architecture, data acquisition system, and preliminary results from experiments with 80-200 keV electron beams.

Improving GPR image resolution in lossy ground using dispersive migration

USGS Publications Warehouse

Oden, C.P.; Powers, M.H.; Wright, D.L.; Olhoeft, G.R.

2007-01-01

As a compact wave packet travels through a dispersive medium, it becomes dilated and distorted. As a result, ground-penetrating radar (GPR) surveys over conductive and/or lossy soils often result in poor image resolution. A dispersive migration method is presented that combines an inverse dispersion filter with frequency-domain migration. The method requires a fully characterized GPR system including the antenna response, which is a function of the local soil properties for ground-coupled antennas. The GPR system response spectrum is used to stabilize the inverse dispersion filter. Dispersive migration restores attenuated spectral components when the signal-to-noise ratio is adequate. Applying the algorithm to simulated data shows that the improved spatial resolution is significant when data are acquired with a GPR system having 120 dB or more of dynamic range, and when the medium has a loss tangent of 0.3 or more. Results also show that dispersive migration provides no significant advantage over conventional migration when the loss tangent is less than 0.3, or when using a GPR system with a small dynamic range. ?? 2007 IEEE.

Electron accommodation dynamics in the DNA base thymine

NASA Astrophysics Data System (ADS)

King, Sarah B.; Stephansen, Anne B.; Yokoi, Yuki; Yandell, Margaret A.; Kunin, Alice; Takayanagi, Toshiyuki; Neumark, Daniel M.

2015-07-01

The dynamics of electron attachment to the DNA base thymine are investigated using femtosecond time-resolved photoelectron imaging of the gas phase iodide-thymine (I-T) complex. An ultraviolet pump pulse ejects an electron from the iodide and prepares an iodine-thymine temporary negative ion that is photodetached with a near-IR probe pulse. The resulting photoelectrons are analyzed with velocity-map imaging. At excitation energies ranging from -120 meV to +90 meV with respect to the vertical detachment energy (VDE) of 4.05 eV for I-T, both the dipole-bound and valence-bound negative ions of thymine are observed. A slightly longer rise time for the valence-bound state than the dipole-bound state suggests that some of the dipole-bound anions convert to valence-bound species. No evidence is seen for a dipole-bound anion of thymine at higher excitation energies, in the range of 0.6 eV above the I-T VDE, which suggests that if the dipole-bound anion acts as a "doorway" to the valence-bound anion, it only does so at excitation energies near the VDE of the complex.

Electron accommodation dynamics in the DNA base thymine.

PubMed

King, Sarah B; Stephansen, Anne B; Yokoi, Yuki; Yandell, Margaret A; Kunin, Alice; Takayanagi, Toshiyuki; Neumark, Daniel M

2015-07-14

The dynamics of electron attachment to the DNA base thymine are investigated using femtosecond time-resolved photoelectron imaging of the gas phase iodide-thymine (I(-)T) complex. An ultraviolet pump pulse ejects an electron from the iodide and prepares an iodine-thymine temporary negative ion that is photodetached with a near-IR probe pulse. The resulting photoelectrons are analyzed with velocity-map imaging. At excitation energies ranging from -120 meV to +90 meV with respect to the vertical detachment energy (VDE) of 4.05 eV for I(-)T, both the dipole-bound and valence-bound negative ions of thymine are observed. A slightly longer rise time for the valence-bound state than the dipole-bound state suggests that some of the dipole-bound anions convert to valence-bound species. No evidence is seen for a dipole-bound anion of thymine at higher excitation energies, in the range of 0.6 eV above the I(-)T VDE, which suggests that if the dipole-bound anion acts as a "doorway" to the valence-bound anion, it only does so at excitation energies near the VDE of the complex.

An evaluation of an ICCD imager of dynamic range expansion technique and application of insitu procedures for life-time extension

NASA Technical Reports Server (NTRS)

Currie, D. G.

1982-01-01

Research toward practical implementation of the Intensified Charge Coupled Device (ICCD) as a photon-counting array detector for astronomy is reported. The first area of concentration was to determine the rate and extent of the lifetime limiting damage to the CCD caused by the impact of high energy electrons, and to find whether various methods of annealing the damage were productive. The second effort was to determine the performance of the ICCD in a photon-counting mode to produce extended dynamic range measurements. There are two main effects that appear as the practical results of the electron damage to the CCD. One is an increase in the leakage current, i.e., the normal thermal generation of charge carriers in the silicon that provides a background dark signal that adds to the light produced image. In an undamaged CCD, the leakage current is usually fairly uniform across the photosensitive area of the silicon chip, with the exception of various bright pixels which have an anomalous leakage current well above the overall level.

Adaptive foveated single-pixel imaging with dynamic supersampling

PubMed Central

Phillips, David B.; Sun, Ming-Jie; Taylor, Jonathan M.; Edgar, Matthew P.; Barnett, Stephen M.; Gibson, Graham M.; Padgett, Miles J.

2017-01-01

In contrast to conventional multipixel cameras, single-pixel cameras capture images using a single detector that measures the correlations between the scene and a set of patterns. However, these systems typically exhibit low frame rates, because to fully sample a scene in this way requires at least the same number of correlation measurements as the number of pixels in the reconstructed image. To mitigate this, a range of compressive sensing techniques have been developed which use a priori knowledge to reconstruct images from an undersampled measurement set. Here, we take a different approach and adopt a strategy inspired by the foveated vision found in the animal kingdom—a framework that exploits the spatiotemporal redundancy of many dynamic scenes. In our system, a high-resolution foveal region tracks motion within the scene, yet unlike a simple zoom, every frame delivers new spatial information from across the entire field of view. This strategy rapidly records the detail of quickly changing features in the scene while simultaneously accumulating detail of more slowly evolving regions over several consecutive frames. This architecture provides video streams in which both the resolution and exposure time spatially vary and adapt dynamically in response to the evolution of the scene. The degree of local frame rate enhancement is scene-dependent, but here, we demonstrate a factor of 4, thereby helping to mitigate one of the main drawbacks of single-pixel imaging techniques. The methods described here complement existing compressive sensing approaches and may be applied to enhance computational imagers that rely on sequential correlation measurements. PMID:28439538

Characterization of Axial Inducer Cavitation Instabilities via High Speed Video Recordings

NASA Technical Reports Server (NTRS)

Arellano, Patrick; Peneda, Marinelle; Ferguson, Thomas; Zoladz, Thomas

2011-01-01

Sub-scale water tests were undertaken to assess the viability of utilizing high resolution, high frame-rate digital video recordings of a liquid rocket engine turbopump axial inducer to characterize cavitation instabilities. These high speed video (HSV) images of various cavitation phenomena, including higher order cavitation, rotating cavitation, alternating blade cavitation, and asymmetric cavitation, as well as non-cavitating flows for comparison, were recorded from various orientations through an acrylic tunnel using one and two cameras at digital recording rates ranging from 6,000 to 15,700 frames per second. The physical characteristics of these cavitation forms, including the mechanisms that define the cavitation frequency, were identified. Additionally, these images showed how the cavitation forms changed and transitioned from one type (tip vortex) to another (sheet cavitation) as the inducer boundary conditions (inlet pressures) were changed. Image processing techniques were developed which tracked the formation and collapse of cavitating fluid in a specified target area, both in the temporal and frequency domains, in order to characterize the cavitation instability frequency. The accuracy of the analysis techniques was found to be very dependent on target size for higher order cavitation, but much less so for the other phenomena. Tunnel-mounted piezoelectric, dynamic pressure transducers were present throughout these tests and were used as references in correlating the results obtained by image processing. Results showed good agreement between image processing and dynamic pressure spectral data. The test set-up, test program, and test results including H-Q and suction performance, dynamic environment and cavitation characterization, and image processing techniques and results will be discussed.

Paediatric interventional cardiology: flat detector versus image intensifier using a test object

NASA Astrophysics Data System (ADS)

Vano, E.; Ubeda, C.; Martinez, L. C.; Leyton, F.; Miranda, P.

2010-12-01

Entrance surface air kerma (ESAK) values and image quality parameters were measured and compared for two biplane angiography x-ray systems dedicated to paediatric interventional cardiology, one equipped with image intensifiers (II) and the other one with dynamic flat detectors (FDs). Polymethyl methacrylate phantoms of different thicknesses, ranging from 8 to 16 cm, and a Leeds TOR 18-FG test object were used. The parameters of the image quality evaluated were noise, signal-difference-to-noise ratio (SdNR), high contrast spatial resolution (HCSR) and three figures of merit combining entrance doses and signal-to-noise ratios or HCSR. The comparisons showed a better behaviour of the II-based system in the low contrast region over the whole interval of thicknesses. The FD-based system showed a better performance in HCSR. The FD system evaluated would need around two times more dose than the II system evaluated to reach a given value of SdNR; moreover, a better spatial resolution was measured (and perceived in conventional monitors) for the system equipped with flat detectors. According to the results of this paper, the use of dynamic FD systems does not lead to an automatic reduction in ESAK or to an automatic improvement in image quality by comparison with II systems. Any improvement also depends on the setting of the x-ray systems and it should still be possible to refine these settings for some of the dynamic FDs used in paediatric cardiology.

Quantitative phase imaging using a programmable wavefront sensor

NASA Astrophysics Data System (ADS)

Soldevila, F.; Durán, V.; Clemente, P.; Lancis, J.; Tajahuerce, E.

2018-02-01

We perform phase imaging using a non-interferometric approach to measure the complex amplitude of a wavefront. We overcome the limitations in spatial resolution, optical efficiency, and dynamic range that are found in Shack-Hartmann wavefront sensing. To do so, we sample the wavefront with a high-speed spatial light modulator. A single lens forms a time-dependent light distribution on its focal plane, where a position detector is placed. Our approach is lenslet-free and does not rely on any kind of iterative or unwrap algorithm. The validity of our technique is demonstrated by performing both aberration sensing and phase imaging of transparent samples.

The robot's eyes - Stereo vision system for automated scene analysis

NASA Technical Reports Server (NTRS)

Williams, D. S.

1977-01-01

Attention is given to the robot stereo vision system which maintains the image produced by solid-state detector television cameras in a dynamic random access memory called RAPID. The imaging hardware consists of sensors (two solid-state image arrays using a charge injection technique), a video-rate analog-to-digital converter, the RAPID memory, and various types of computer-controlled displays, and preprocessing equipment (for reflexive actions, processing aids, and object detection). The software is aimed at locating objects and transversibility. An object-tracking algorithm is discussed and it is noted that tracking speed is in the 50-75 pixels/s range.

Earth Observing-1 Advanced Land Imager: Radiometric Response Calibration

NASA Technical Reports Server (NTRS)

Mendenhall, J. A.; Lencioni, D. E.; Evans, J. B.

2000-01-01

The Advanced Land Imager (ALI) is one of three instruments to be flown on the first Earth Observing mission (EO-1) under NASA's New Millennium Program (NMP). ALI contains a number of innovative features, including a wide field of view optical design, compact multispectral focal plane arrays, non-cryogenic HgCdTe detectors for the short wave infrared bands, and silicon carbide optics. This document outlines the techniques adopted during ground calibration of the radiometric response of the Advanced Land Imager. Results from system level measurements of the instrument response, signal-to-noise ratio, saturation radiance, and dynamic range for all detectors of every spectral band are also presented.

Novel computer-based endoscopic camera

NASA Astrophysics Data System (ADS)

Rabinovitz, R.; Hai, N.; Abraham, Martin D.; Adler, Doron; Nissani, M.; Fridental, Ron; Vitsnudel, Ilia

1995-05-01

We have introduced a computer-based endoscopic camera which includes (a) unique real-time digital image processing to optimize image visualization by reducing over exposed glared areas and brightening dark areas, and by accentuating sharpness and fine structures, and (b) patient data documentation and management. The image processing is based on i Sight's iSP1000TM digital video processor chip and Adaptive SensitivityTM patented scheme for capturing and displaying images with wide dynamic range of light, taking into account local neighborhood image conditions and global image statistics. It provides the medical user with the ability to view images under difficult lighting conditions, without losing details `in the dark' or in completely saturated areas. The patient data documentation and management allows storage of images (approximately 1 MB per image for a full 24 bit color image) to any storage device installed into the camera, or to an external host media via network. The patient data which is included with every image described essential information on the patient and procedure. The operator can assign custom data descriptors, and can search for the stored image/data by typing any image descriptor. The camera optics has extended zoom range of f equals 20 - 45 mm allowing control of the diameter of the field which is displayed on the monitor such that the complete field of view of the endoscope can be displayed on all the area of the screen. All these features provide versatile endoscopic camera with excellent image quality and documentation capabilities.

Better Pictures in a Snap

NASA Technical Reports Server (NTRS)

2002-01-01

Retinex Imaging Processing, winner of NASA's 1999 Space Act Award, is commercially available through TruView Imaging Company. With this technology, amateur photographers use their personal computers to improve the brightness, scene contrast, detail, and overall sharpness of images with increased ease. The process was originally developed for remote sensing of the Earth by researchers at Langley Research Center and Science and Technology Corporation (STC). It automatically enhances a digital image in terms of dynamic range compression, color independence from the spectral distribution of the scene illuminant, and color/lightness rendition. As a result, the enhanced digital image is much closer to the scene perceived by the human visual system, under all kinds and levels of lighting variations. TruView believes there are other applications for the software in medical imaging, forensics, security, recognizance, mining, assembly, and other industrial areas.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kleissl, J.; Urquhart, B.; Ghonima, M.

During the University of California, San Diego (UCSD) Sky Imager Cloud Position Study, two University of California, San Diego Sky Imagers (USI) (Figure 1) were deployed the U.S. Department of Energy(DOE)’s Atmospheric Radiation Measurement (ARM) Climate Research Facility Southern Great Plains SGP) research facility. The UCSD Sky Imagers were placed 1.7 km apart to allow for stereographic determination of the cloud height for clouds over approximately 1.5 km. Images with a 180-degree field of view were captured from both systems during daylight hours every 30 seconds beginning on March 11, 2013 and ending on November 4, 2013. The spatial resolutionmore » of the images was 1,748 × 1,748, and the intensity resolution was 16 bits using a high-dynamic-range capture process. The cameras use a fisheye lens, so the images are distorted following an equisolid angle projection.« less

Effect of probe diffusion on the SOFI imaging accuracy.

PubMed

Vandenberg, Wim; Dedecker, Peter

2017-03-23

Live-cell super-resolution fluorescence imaging is becoming commonplace for exploring biological systems, though sample dynamics can affect the imaging quality. In this work we evaluate the effect of probe diffusion on super-resolution optical fluctuation imaging (SOFI), using a theoretical model and numerical simulations based on the imaging of live cells labelled with photochromic fluorescent proteins. We find that, over a range of physiological conditions, fluorophore diffusion results in a change in the amplitude of the SOFI signal. The magnitude of this change is approximately proportional to the on-time ratio of the fluorophores. However, for photochromic fluorescent proteins this effect is unlikely to present a significant distortion in practical experiments in biological systems. Due to this lack of distortions, probe diffusion strongly enhances the SOFI imaging by avoiding spatial undersampling caused by the limited labeling density.

Preparing Colorful Astronomical Images and Illustrations

NASA Astrophysics Data System (ADS)

Levay, Z. G.; Frattare, L. M.

2001-12-01

We present techniques for using mainstream graphics software, specifically Adobe Photoshop and Illustrator, for producing composite color images and illustrations from astronomical data. These techniques have been used with numerous images from the Hubble Space Telescope to produce printed and web-based news, education and public presentation products as well as illustrations for technical publication. While Photoshop is not intended for quantitative analysis of full dynamic range data (as are IRAF or IDL, for example), we have had much success applying Photoshop's numerous, versatile tools to work with scaled images, masks, text and graphics in multiple semi-transparent layers and channels. These features, along with its user-oriented, visual interface, provide convenient tools to produce high-quality, full-color images and graphics for printed and on-line publication and presentation.

Method to Enhance the Operation of an Optical Inspection Instrument Using Spatial Light Modulators

NASA Technical Reports Server (NTRS)

Trolinger, James; Lal, Amit; Jo, Joshua; Kupiec, Stephen

2012-01-01

For many aspheric and freeform optical components, existing interferometric solutions require a custom computer-generated hologram (CGH) to characterize the part. The overall objective of this research is to develop hardware and a procedure to produce a combined, dynamic, Hartmann/ Digital Holographic interferometry inspection system for a wide range of advanced optical components, including aspheric and freeform optics. This new instrument would have greater versatility and dynamic range than currently available measurement systems. The method uses a spatial light modulator to pre-condition wavefronts for imaging, interferometry, and data processing to improve the resolution and versatility of an optical inspection instrument. Existing interferometers and Hartmann inspection systems have either too small a dynamic range or insufficient resolution to characterize conveniently unusual optical surfaces like aspherical and freeform optics. For interferometers, a specially produced, computer-generated holographic optical element is needed to transform the wavefront to within the range of the interferometer. A new hybrid wavefront sensor employs newly available spatial light modulators (SLMs) as programmable holographic optical elements (HOEs). The HOE is programmed to enable the same instrument to inspect an optical element in stages, first by a Hartmann measurement, which has a very large dynamic range but less resolution. The first measurement provides the information required to precondition a reference wave that avails the measurement process to the more precise phase shifting interferometry. The SLM preconditions a wavefront before it is used to inspect an optical component. This adds important features to an optical inspection system, enabling not just wavefront conditioning for null testing and dynamic range extension, but also the creation of hybrid measurement procedures. This, for example, allows the combination of dynamic digital holography and Hartmann sensing procedures to cover a virtually unlimited dynamic range with high resolution. Digital holography technology brings all of the power and benefits of digital holographic interferometry to the requirement, while Hartmann-type wavefront sensors bring deflectometry technologies to the solution. The SLM can be used to generate arbitrary wavefronts in one leg of the interferometer, thereby greatly simplifying its use and extending its range. The SLM can also be used to modify the system into a dynamic Shack-Hartmann system, which is useful for optical components with large amounts of slope. By integrating these capabilities into a single instrument, the system will have tremendous flexibility to measure a variety of optical shapes accurately.

Motion effects in multistatic millimeter-wave imaging systems

NASA Astrophysics Data System (ADS)

Schiessl, Andreas; Ahmed, Sherif Sayed; Schmidt, Lorenz-Peter

2013-10-01

At airport security checkpoints, authorities are demanding improved personnel screening devices for increased security. Active mm-wave imaging systems deliver the high quality images needed for reliable automatic detection of hidden threats. As mm-wave imaging systems assume static scenarios, motion effects caused by movement of persons during the screening procedure can degrade image quality, so very short measurement time is required. Multistatic imaging array designs and fully electronic scanning in combination with digital beamforming offer short measurement time together with high resolution and high image dynamic range, which are critical parameters for imaging systems used for passenger screening. In this paper, operational principles of such systems are explained, and the performance of the imaging systems with respect to motion within the scenarios is demonstrated using mm-wave images of different test objects and standing as well as moving persons. Electronic microwave imaging systems using multistatic sparse arrays are suitable for next generation screening systems, which will support on the move screening of passengers.

CMOS detector arrays in a virtual 10-kilopixel camera for coherent terahertz real-time imaging.

PubMed

Boppel, Sebastian; Lisauskas, Alvydas; Max, Alexander; Krozer, Viktor; Roskos, Hartmut G

2012-02-15

We demonstrate the principle applicability of antenna-coupled complementary metal oxide semiconductor (CMOS) field-effect transistor arrays as cameras for real-time coherent imaging at 591.4 GHz. By scanning a few detectors across the image plane, we synthesize a focal-plane array of 100×100 pixels with an active area of 20×20 mm2, which is applied to imaging in transmission and reflection geometries. Individual detector pixels exhibit a voltage conversion loss of 24 dB and a noise figure of 41 dB for 16 μW of the local oscillator (LO) drive. For object illumination, we use a radio-frequency (RF) source with 432 μW at 590 GHz. Coherent detection is realized by quasioptical superposition of the image and the LO beam with 247 μW. At an effective frame rate of 17 Hz, we achieve a maximum dynamic range of 30 dB in the center of the image and more than 20 dB within a disk of 18 mm diameter. The system has been used for surface reconstruction resolving a height difference in the μm range.

Characterization of NPP Visible/Infrared Imager Radiometer Suite (VIIRS) Reflective Solar Bands Dual Gain Anomaly

NASA Technical Reports Server (NTRS)

Lee, Shihyan; McIntire, Jeff; Oudari, Hassan

2012-01-01

The Visible/Infrared Imager Radiometer Suite (VIIRS) contains six dual gain bands in the reflective solar spectrum. The dual gain bands are designed to switch gain mode at pre-defined thresholds to achieve high resolution at low radiances while maintaining the required dynamic range for science. During pre-launch testing, an anomaly in the electronic response before transitioning from high to low gain was discovered and characterized. On-orbit, the anomaly was confirmed using MODIS data collected during Simultaneous Nadir Overpasses (SNOs). The analysis of the Earth scene data shows that dual gain anomaly can be determined at the orbital basis. To characterize the dual gain anomaly, the anomaly region and electronic offsets were tracked per week during the first 8 month of VIIRS operation. The temporal analysis shows the anomaly region can drift 20 DN and is impacted by detectors DC Restore. The estimated anomaly flagging regions cover 2.5 % of the high gain dynamic range and are consistent with prelaunch and on-orbit LUT. The prelaunch results had a smaller anomaly range (30-50 DN) and are likely the results of more stable electronics from the shorter data collection time. Finally, this study suggests future calibration efforts to focus on the anomaly's impact on science products and possible correction method to reduce uncertainties.

Dynamic laser beam shaping for material processing using hybrid holograms

NASA Astrophysics Data System (ADS)

Liu, Dun; Wang, Yutao; Zhai, Zhongsheng; Fang, Zheng; Tao, Qing; Perrie, Walter; Edwarson, Stuart P.; Dearden, Geoff

2018-06-01

A high quality, dynamic laser beam shaping method is demonstrated by displaying a series of hybrid holograms onto a spatial light modulator (SLM), while each one of the holograms consists of a binary grating and a geometric mask. A diffraction effect around the shaped beam has been significantly reduced. Beam profiles of arbitrary shape, such as square, ring, triangle, pentagon and hexagon, can be conveniently obtained by loading the corresponding holograms on the SLM. The shaped beam can be reconstructed in the range of 0.5 mm at the image plane. Ablation on a polished stainless steel sample at the image plane are consistent with the beam shape at the diffraction near-field. The ±1st order and higher order beams can be completely removed when the grating period is smaller than 160 μm. The local energy ratio of the shaped beam observed by the CCD camera is up to 77.67%. Dynamic processing at 25 Hz using different shapes has also been achieved.