Using Residential Solar Photovoltaic Quote Data to Analyze the Relationship

Science.gov Websites

installers accounted for more than 60% of systems. This report analyzes the effects of this market residential PV quotes from the third-party quote provider EnergySage to study the effects of installer size on

{open_quotes}Full steam ahead{close_quotes} (a historical review of geothermal power development in the Philippines)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gazo, F.M.

1997-12-31

The Philippine geothermal energy development is now considered in a state of maturity. After more than 20 years of geothermal experience, the total geothermal installed capacity in the Philippines reached 1,455 MW (1996) or about 12% of the total installed power plant capacity. This also enabled the Philippines to become the second largest producer of geothermal energy in the world. The country`s track record in harnessing geothermal energy is considered a revelation, as it continues with its vision of {open_quotes}full steam ahead{close_quotes}, originally conceived when commercial geothermal operation started in 1973. It is thus proper and timely to refer tomore » historical highlights and experiences in geothermal energy development for planning and implementation of the country`s geothermal energy program.« less

Progress report No. 2, design of new pile area {open_quotes}G,{close_quotes} Project C-300, Atomic Energy Commission Directive HW-104

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowe, P.E.

1950-01-16

This document is the progress report for the design and development of Pile Area {open_quotes}G{close_quotes}, to cover the period June 1, 1949 to December 31, 1949. This project represents the major effort of the Reactor Division of the Design and Construction Divisions. It is being pursued with the aim of being able to incorporate the major project objectives in a finished pile design if that design is begun about January, 1951.

{open_quotes}Airborne Research Australia (ARA){close_quotes} a new research aircraft facility on the southern hemisphere

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hacker, J.M.

1996-11-01

{open_quotes}Airborne Research Australia{close_quotes} (ARA) is a new research aircraft facility in Australia. It will serve the scientific community of Australia and will also make its aircraft and expertise available for commercial users. To cover the widest possible range of applications, the facility will operate up to five research aircraft, from a small, low-cost platform to medium-sized multi-purpose aircraft, as well as a unique high altitude aircraft capable of carrying scientific loads to altitudes of up to 15km. The aircraft will be equipped with basic instrumentation and data systems, as well as facilities to mount user-supplied instrumentation and systems internally andmore » externally on the aircraft. The ARA operations base consisting of a hangar, workshops, offices, laboratories, etc. is currently being constructed at Parafield Airport near Adelaide/South Australia. The following text reports about the current state of development of the facility. An update will be given in a presentation at the Conference. 6 figs.« less

Great Quotes To Inspire Great Teachers.

ERIC Educational Resources Information Center

benShea, Noah

This book provides a collection of quotes designed to offer support and inspiration to teachers as they face the daily emotional, spiritual, intellectual, and physical challenges of their professional and personal lives. The book's 26 sections focus on: the art of teaching; adversity; behavior; character; children; collaboration and teamwork;…

Development of the simulation system {open_quotes}IMPACT{close_quotes} for analysis of nuclear power plant severe accidents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Naitoh, Masanori; Ujita, Hiroshi; Nagumo, Hiroichi

1997-07-01

The Nuclear Power Engineering Corporation (NUPEC) has initiated a long-term program to develop the simulation system {open_quotes}IMPACT{close_quotes} for analysis of hypothetical severe accidents in nuclear power plants. IMPACT employs advanced methods of physical modeling and numerical computation, and can simulate a wide spectrum of senarios ranging from normal operation to hypothetical, beyond-design-basis-accident events. Designed as a large-scale system of interconnected, hierarchical modules, IMPACT`s distinguishing features include mechanistic models based on first principles and high speed simulation on parallel processing computers. The present plan is a ten-year program starting from 1993, consisting of the initial one-year of preparatory work followed bymore » three technical phases: Phase-1 for development of a prototype system; Phase-2 for completion of the simulation system, incorporating new achievements from basic studies; and Phase-3 for refinement through extensive verification and validation against test results and available real plant data.« less

{open_quotes}Horizontal{close_quotes} gene transfer from a transgenic potato line to a bacterial pathogen (Erwinia chrysanthemi) occurs - if at all - at an extremely low frequency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schlueter, K.; Fuetterer, J.; Potrykus, I.

1995-10-01

The frequency of possible {open_quotes}horizontal{close_quotes} gene transfer between a plant and a tightly associated bacterial pathogen was studied in a model system consisting of transgenic Solanum tuberosum, containing a {beta}-lactamase gene linked to a pBR322 origin of replication, and Erwinia chrysanthemi. This experimental system offers optimal conditions for the detection of possible horizontal gene transfer events, even when they occur at very low frequency. Horizontal gene transfer was not detected under conditions mimicking a {open_quotes}natural{close_quotes} infection. The gradual, stepwise alteration of artificial, positive control conditions to idealized natural conditions, however, allowed the characterization of factors that affected gene transfer, andmore » revealed a gradual decrease of the gene transfer frequency from 6.3 x 10{sup -2} under optimal control conditions to a calculated 2.0 x 10{sub -17} under idealized natural conditions. These data, in combination with other published studies, argue that horizontal gene transfer is so rare as to be essentially irrelevant to any realistic assessment of the risk involved in release experiments involving transgenic plants. 22 refs., 3 figs., 2 tabs.« less

Introduction of artificial pinning centre in {open_quotes}Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8}{close_quotes} ceramics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Majewski, P.; Aldinger, F.; Elschner, S.

1994-12-31

Considering the phase equilibrium diagram of the system Bi{sub 2}O{sub 3}-SrO-CaO-CuO, single phase {open_quotes}Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8}{close_quotes} ceramics have been transformed by a simple annealing procedure into multi phase samples. The transformation results in the formation of second phases and in an increase of the intra grain critical current density at 1 T of five times. This increase is believed to express improved pinning properties of the superconducting crystals. The prepared pinning centres are believed to be e.g. coherent precipitates (Guinier-Preston-zones) within the superconducting crystals.

Crossed and Locked Quotes in a Multi-Market Simulation

PubMed Central

Todd, Andrew; Beling, Peter; Scherer, William

2016-01-01

Financial markets are often fragmented, introducing the possibility that quotes in identical securities may become crossed or locked. There are a number of theoretical explanations for the existence of crossed and locked quotes, including competition, simultaneous actions, inattentiveness, fee structure and market access. In this paper, we perform a simulation experiment designed to examine the effect of simple order routing procedures on the properties of a fragmented market consisting of a single security trading in two independent limit order books. The quotes in the two markets are connected solely by the routing decision of the market participants. We report on the health of the consolidated market as measured by the duration of crossed and locked states, as well as the spread and the volatility of transaction prices in the consolidated market. We aim to quantify exactly how the prevalence of order routing among a population of market participants affects properties of the consolidated market. Our model contributes to the zero-intelligence literature by treating order routing as an experimental variable. Additionally, we introduce a parsimonious heuristic for limit order routing, allowing us to study the effects of both market order routing and limit order routing. Our model refines intuition for the sometimes subtle relationships between the prevalence of order routing and various market measures. Our model also provides a benchmark for more complex agent-based models. PMID:26959416

Crossed and Locked Quotes in a Multi-Market Simulation.

PubMed

Todd, Andrew; Beling, Peter; Scherer, William

2016-01-01

Financial markets are often fragmented, introducing the possibility that quotes in identical securities may become crossed or locked. There are a number of theoretical explanations for the existence of crossed and locked quotes, including competition, simultaneous actions, inattentiveness, fee structure and market access. In this paper, we perform a simulation experiment designed to examine the effect of simple order routing procedures on the properties of a fragmented market consisting of a single security trading in two independent limit order books. The quotes in the two markets are connected solely by the routing decision of the market participants. We report on the health of the consolidated market as measured by the duration of crossed and locked states, as well as the spread and the volatility of transaction prices in the consolidated market. We aim to quantify exactly how the prevalence of order routing among a population of market participants affects properties of the consolidated market. Our model contributes to the zero-intelligence literature by treating order routing as an experimental variable. Additionally, we introduce a parsimonious heuristic for limit order routing, allowing us to study the effects of both market order routing and limit order routing. Our model refines intuition for the sometimes subtle relationships between the prevalence of order routing and various market measures. Our model also provides a benchmark for more complex agent-based models.

The restructuring and future of {open_quotes}Mendelian Inheritance in Man{close_quotes} (MIM)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pearson, P.L.; Francomano, C.; Antonarakis, S.

1994-09-01

Victor McKusick`s catalog {open_quotes}Mendelian Inheritance in Man{close_quotes} represents the most comprehensive compendum of human genetic disease information available today and has appeared as a series in book form for the last 30 years. The 11th edition will contain almost 7000 entries: approximately 2800 descriptions of human genetic disorders, 700 combined disorder/gene descriptions and 3500 pure gene descriptions. Until recently the content of the catalogs was maintained solely by McKusick with a support staff. However, a distributed editing system has now been established with the following primary components. New entries are initiated in Baltimore by science writers under the guidance ofmore » the senior editors and McKusick, following which the information is made immediately available to the public through online access. The subject editors can then review and edit the new or modified information without impeding the timeliness of entering new information. Entries are being reconstructured so that clinical disorder and gene information is divided into separate entries which will better represent the frequently complex relationship of gene mutations to individual clinical disorders in the data files. Further, each entry is being subdivided into logical topics which will enhance the power of electronic searching, making links between topics and improving readability. The old division of entries into autosomal dominant and recessive, etc., is being abandoned in favor of clinical disorder (phenotypes) and gene catalogs. The information is maintained in an SGML format which facilitates the production of many different types of output varying from the traditional book form to CD ROMs and various online formats including IRx, WAIS, Gopher and World Wide Web. This latter offers the exciting possibility of making hypertext links between entries and other data resources, including photographic, sound and video clips as part of the total MIM information.« less

Translocation 4p;21q identified by FISH in a case previously described as {open_quotes}presumptive monosomy 21{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yao, Xiu-Lan; Jenkins, E.C.

1994-10-01

Recently, Lopez-Pajares et al. (1993) reported identification of a translocation between the short arm of a chromosome 5 and the long arm of a chromosome 21 in a patient who was thought to be monosomy 21. This study is the first application of a chromosome 21 painting probe, pBS-21, and fluorescent in situ chromosome hybridization (FISH) to revise an earlier diagnosis of monosomy 21. We have now restudied skin fibroblast cultures, GM00137B, that are still available from another patient previously described as {open_quotes}presumptive monosomy 21{close_quotes} and have found that this case also has a translocation involving chromosomes 21 and 4.more » The authors urge that all previous cases of what appeared to be monosomy 21 should be re-examined with FISH to confirm or revise the original diagnosis so that genetic counseling of the family may be updated. 3 refs., 3 figs.« less

Racist Quotes from Persons of Note, Part II.

ERIC Educational Resources Information Center

Fikes, Robert, Jr.

1988-01-01

Offers racist quotes about Blacks, Jews, Hispanics, Asians, Italians, Poles, and others, from famous persons such as John Wayne, Woodrow Wilson, William F. Buckley, Richard Wagner, Jesse Helms, Sam Rayburn, Walter Lippman, Jack London, Paul Lynde, Theodore Roosevelt, Frank Sinatra, Errol Flynn, Ezra Pound, Richard M. Nixon, and Ronald Reagan. (BJV)

{open_quotes}Bubble fusion{close_quotes}: Preliminary estimates of spherical micro-implosions in cavitating liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krakowski, R.A.

1995-02-01

Liquids irradiated with intense ultrasonic waves can generate small cavities or bubbles. Upon nonlinear expansion to a state of disequilibrium, wherein the externally imposed hydrostatic pressure far exceeds that of entrapped non-condensable gas, these bubbles undergo a rapid and violent collapse. This collapse, if symmetric, can generate high pressures and temperatures through a number of possible mechanisms. The simplest and oldest explanation suggests a focusing of the kinetic energy of all the surrounding liquid onto the collapsing bubble and the subsequent heating of entrapped gases under either adiabatic or isothermal conditions. Although induced by externally imposed millisecond pressure oscillations, thesemore » collapses can occur on sub-microsecond timescales and are accompanied by picosecond light emissions; this combination of sound and light is called sonoluminescence. Recent explanations of observed high temperatures and picosecond radiation pulses accompanying such collapses are based on the interaction of multiple shock waves that are launched off the inward cavity wall. Other potential explanations invoke dipole emissions induced by intermolecular collisions or the release of Casimir energy when a dielectric hole is filled. Conjectures have been made that the processes responsible for sonoluminescence may be extended to generated conditions where thermonuclear fusion might occur. Such an achievement would extend scientific interest in sonoluminescence out of a purely chemical context to include the study of matter subjected to more extreme conditions. The main goal of this {open_quotes}scoping{close_quotes} study is to understand better conditions where deuterium-tritium fusion might be observed in conjunction with micro-implosions in cavitating liquids; prognoses of fusion application at this point are unintended.« less

The results of the investigations of Russian Research Center - {open_quotes}Kurchatov Institute{close_quotes} on molten salt applications to problems of nuclear energy systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Novikov, V.M.

1995-10-01

The results of investigations on molten salt (MS) applications to problems of nuclear energy systems that have been conducted in Russian Research {open_quotes}Kurchatov Institute{close_quotes} are presented and discussed. The spectrum of these investigations is rather broad and covers the following items: physical characteristics of molten salt nuclear energy systems (MSNES); nuclear and radiation safety of MSNES; construction materials compatible with MS of different compositions; technological aspects of MS loops; in-reactor loop testing. It is shown that main findings of completed program support the conclusion that there are no physical nor technological obstacles on way of MS application to different nuclearmore » energy systems.« less

400 Quotable Quotes from the World's Leading Educators

ERIC Educational Resources Information Center

Sennett, Frank

2004-01-01

This book represents a showcase of thoughts on important education issues by groundbreakers such as Dewey, Montessori, and Bloom as well as contemporary educators like Fullan, Glasser, and Lambert. The reader will find a wealth of subjects, indexed under dozens of pertinent headings. Included are: (1) Inspirational quotes to apply to any project…

Quotable Quotes on the Value of Language Study.

ERIC Educational Resources Information Center

Language Association Bulletin, 1974

1974-01-01

Quotations about the importance of and need for foreign language teaching and learning by well-known U. S. politicians, college and university presidents, religious leaders, and government officials are presented. Those quoted include: (1) J. M. Leslie; (2) E. Nyquist; (3) J. M. Hester; (4) C. B. Saunders; (5) L. White, Jr.; (6) H. Humphrey; (7)…

An EXAFS study on the so-called {open_quotes}Co-Mo-S{close_quotes} phase in Co/C and CoMo/C, compared with a Moessbauer emission spectroscopy study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Craje, M.W.J.; Kraan, A.M. van der; Louwers, S.P.A.

1992-06-25

EXAFS was used in this paper to study 4 sulfided catalysts that have the same structure as their {sup 57}Co counterparts characterized by Mossbauer emission spectroscopy. The {open_quotes}Co-Mo-S{close_quotes} phase in Co/C is similar to CoMo/C due to a very highly dispersed Co species. Without Mo, the sulfidic Co results in a Co{sub 9}S{sub 8} phase during sulfidation at 673K, Mo prevents Co sintering in CoMo/C. 37 refs., 6 figs., 2 tabs.

Imaging of neuroendocrine tumors in 300 patients following injection of I-123 mIBG or 1-131 mIBG prepared from a {open_quotes}cold kit{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karesh, S.M.; Henkin, R.E.

1994-05-01

During the past 6 years, we have performed approximately 300 scans for neuroendocrine tumors in an extremely varied patient base, with 65% of patients receiving I-123 mIBG and 35%, I-131 mIBG. Imaging was performed at 24-72 hr, depending upon the isotope used. The most common clinical indication was for pheochromocytoma (>90%), followed by neuroblastoma, paraganglioma, medullary carcinoma of the thyroid, and carcinoid tumors. Radiolabeling was performed by a modification of Mock`s procedure. The radioiodide was added to a very stable {open_quotes}cold kit{close_quotes} developed in-house. The kit contains 1 ml of water for injection, 2 mg of mIBG hemisulfate, and 12more » mg of ammonium sulfate. After 2 heating cycles, a yield >85% and a radiochemical purity {>=}96% were routinely obtained. Overall preparation time, including determination of radiochemical purity, is approximately 2.5 hr. The only equipment required is a thermostatically controlled block heater. Biodistribution of our I-131 product was indistinguishable from that distributed by the Nuclear Pharmacy at the University of Michigan, as was the radiochemical purity; the diagnostic efficacy matched that reported in the literature. The image quality obtained using I-123 mIBG was definitely superior, due to both the much higher count rate and the ideal imaging energy of I-123. On one occasion, the I-131 scan was equivocal, whereas the I-123 scan in the same patient was clearly positive. Retrospectively, for studies performed with I-123 mIBG using the {open_quotes}cold kit{close_quotes} method, the specificity and sensitivity both exceed 90%, correlating well with multiple studies reported in the literature. The preparation of I-123 mIBG in-house using this technique is recommended.« less

3-D architecture modeling using high-resolution seismic data and sparse well control: Example from the Mars {open_quotes}Pink{close_quotes} reservoir, Mississippi Canyon Area, Gulf of Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chapin, M.A.; Tiller, G.M.; Mahaffie, M.J.

1996-12-31

Economic considerations of the deep-water turbidite play, in the Gulf of Mexico and elsewhere, require large reservoir volumes to be drained by relatively few, very expensive wells. Deep-water development projects to date have been planned on the basis of high-quality 3-D seismic data and sparse well control. The link between 3-D seismic, well control, and the 3-D geological and reservoir architecture model are demonstrated here for Pliocene turbidite sands of the {open_quotes}Pink{close_quotes} reservoir, Prospect Mars, Mississippi Canyon Areas 763 and 807, Gulf of Mexico. This information was used to better understand potential reservoir compartments for development well planning.

Linkage of early-onset osteoarthritis and chondrocalcinosis to human chromosome 8q

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baldwin, C.T.; Farrer, L.A.; Adair, R.

Calcium pyrophosphate-deposition disease (CPDD), also called {open_quotes}chondrocalcinosis{close_quotes} or {open_quotes}pseudogout{close_quotes}, is a disorder characterized by the deposition of calcium-containing crystals in joint tissue, which leads to arthritis-like symptoms. The presence of these crystals in joint tissue is a common finding in the elderly, and, in this population, there is a poor correlation with joint pain. In contrast, early-onset CPDD has been described in several large families in which the disease progresses to severe degenerative osteoarthritis (OA). In these families, an autosomal dominant mode of inheritance is observed, with an age at onset between the 2nd and 5th decades of life. Inmore » this report, we describe a large New England family with early-onset CPDD and severe degenerative OA. We found genetic linkage between the disease in this family and chromosome 8q, with a multipoint lod score of 4.06. These results suggest that a defective gene at this location causes the disease in this family. 29 refs., 2 figs., 1 tab.« less

Segregation analysis of Alzheimer pedigrees: Rare Mendelian dominant mutation(s) explain a minority of early-onset cases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martinez, M.; Campion, D.; Babron, M.C.

1996-02-16

Segregation analysis of Alzheimer disease (AD) in 92 families ascertained through early-onset ({le}age 60 years) AD (EOAD) probands has been carried out, allowing for a mixture in AD inheritance among probands. The goal was to quantify the proportion of probands that could be explained by autosomal inheritance of a rare disease allele {open_quotes}a{close_quotes} at a Mendelian dominant gene (MDG). Our data provide strong evidence for a mixture of two distributions; AD transmission is fully explained by MDG inheritance in <20% of probands. Male and female age-of-onset distributions are significantly different for {open_quotes}AA{close_quote} but not for {open_quotes}aA{close_quote} subjects. For {open_quotes}aA{close_quote} subjectsmore » the estimated penetrance value was close to 1 by age 60. For {open_quotes}AA{close_quotes} subjects, it reaches, by age 90, 10% (males) and 30% (females). We show a clear cutoff in the posterior probability of being an MDG case. 10 refs., 1 tab.« less

Finding a [open quotes]proposal[close quotes] for major federal action consistent with the purposes of NEPA: Does Blue Ocean Preservation Society v. Watkins breathe new life into the law

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, V.

Blue Ocean Preservation Society vs. Watkins (BOPS), the subject of this casenote, exemplifies the need for consideration of the environmental consequences of an agency action. The geothermal energy project which was the subject of that litigation involved sensitive, highly controversial and cultural concerns. BOPS illustrates the most compelling case for requiring preparation of an EIS before the decision to undertake agency action. This article addresses the question of what constitutes a [open quotes]proposal[close quotes] for purposes of compelling federal agencies to prepare EIS's pursuant to NEPA. Specifically, this casenote examines the method by which the Court found a proposal formore » major federal action in BOPS.« less

Using Residential Solar PV Quote Data to Analyze the Relationship Between Installer Pricing and Firm Size

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Shaughnessy, Eric; Margolis, Robert

2017-05-18

We use residential solar photovoltaic (PV) quote data to study the role of firm size in PV installer pricing. We find that large installers (those that installed more than 1,000 PV systems in any year from 2013 to 2015) quote higher prices for customer-owned systems, on average, than do other installers. The results suggest that low prices are not the primary value proposition of large installers.

Using Residential Solar PV Quote Data to Analyze the Relationship Between Installer Pricing and Firm Size

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Shaughnessy, Eric; Margolis, Robert

2017-05-19

We use residential solar photovoltaic (PV) quote data to study the role of firm size in PV installer pricing. We find that large installers (those that installed more than 1,000 PV systems in any year from 2013 to 2015) quote higher prices for customer-owned systems, on average, than do other installers. The results suggest that low prices are not the primary value proposition of large installers.

Depositional facies and porosity development at Coon Creek Field (Newman [open quotes]Big Lime[close quotes]), Leslie County, Kentucky

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moshier, S.O.; Stamper, M.E.

1994-08-01

Coon Creek field is a significant petroleum reservoir in the [open quotes]Big Lime[close quotes], Middle to Upper Mississippian Newman equivalent, in southeastern Kentucky. Initial production from select wells has exceeded 600 bbl of oil/day at drilling depths averaging 915 m (3300 ft). Facies patterns, dolomitization, porosity, and structure in this carbonate reservoir have been delineated by geophysical logs, subsurface mapping, and examination of cores and cuttings. The reservoir is set within a localized paleotopographic low on the unconformable surface of the underlying siliciclastic Borden Group; the Borden surface can express rapid relief of over a 10% grade within less thanmore » 300 m. Transgression across the exposed Borden surface resulted in the deposition of a complex system of carbonates lithofacies. Crinoidal dolostones, representing shallow subtidal skeletal bars and banks, form the basal Big Lime (1.5-6 m thick). They are overlain by a typical facies (30 m thick) of bryozoan grainstones/packstones, crinoid grainstones, and mixed skeletal wakestones/mudstones. The rybryozoanacies are characterized by unfragmented fenestrates cemented by radiaxial-fibrous calcite. Stratigraphic distributions indicate the bryozoan facies were broad buildups with crinoidal flank and cap deposits and muddy skeletal off-mount facies, similar to deeper water Waulsortian mounds in other basins. Pellet and ooid grainstones represent moderate- to high-energy subtidal shoal deposits that covered the mound complex. Hydrocarbon production is restricted in the field to the crinoid-bryozoan facies complex within the basal 30 m. Reservoir porosity and permeability have been enhanced by selective dolomitization of grainstones and fracturing related to postdepositional reactivation of basement faults.« less

Using Residential Solar PV Quote Data to Analyze the Relationship Between Installer Pricing and Firm Size

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Shaughnessy, Eric; Margolis, Robert

2017-04-01

The vast majority of U.S. residential solar PV installers are small local-scale companies, however the industry is relatively concentrated in a few large national-scale installers. We develop a novel approach using solar PV quote data to study the price behavior of large solar PV installers in the United States. Through a paired differences approach, we find that large installer quotes are about higher, on average, than non-large installer quotes made to the same customer. The difference is statistically significant and robust after controlling for factors such as system size, equipment quality, and time effects. The results suggest that low pricesmore » are not the primary value proposition of large installer systems. We explore several hypotheses for this finding, including that large installers are able to exercise some market power and/or earn returns from reputations.« less

Hypothesis: {open_quotes}Rogue cell{close_quotes}-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncopenesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neel, J.V.; Glover, T.; Burgess, A.

The hemagglutination inhibition antibody titers against the JC and BK polyoma viruses (JCV and BKV, respectively) are significantly elevated in individuals exhibiting {open_quotes}rogue{close_quotes} cells among their cultured lymphocytes. However, the elevation is so much greater with respect to JCV that the BKV elevation could readily be explained by cross reactivity to the capsid protein of these two closely related viruses. The JCV exhibits highly sequence homology with the simian papovavirus, simian virus 40 (SV40), and inoculation of human fetal brain cells with JCV produces polyploidy and chromosomal damage very similar to that produced by SV40. We suggest, by analogy withmore » the effects of SV40, that these changes are due to the action of the viral large tumor antigen, a pluripotent DNA binding protein that acts in both transcription and replication. The implications of these findings for oncogenesis are briefly discussed. 45 refs., 1 fig., 3 tabs.« less

3D architecture modeling of reservoir compartments in a Shingled Turbidite Reservoir using high-resolution seismic data and sparse well control, example from Mars {open_quotes}Pink{close_quotes} reservoir, Mississippi Canyon Area, Gulf of Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chapin, M.A.; Mahaffie, M.J.; Tiller, G.M.

1996-12-31

Economics of most deep-water development projects require large reservoir volumes to be drained with relatively few wells. The presence of reservoir compartments must therefore be detected and planned for in a pre-development stage. We have used 3-D seismic data to constrain large-scale, deterministic reservoir bodies in a 3-D architecture model of Pliocene-turbidite sands of the {open_quotes}E{close_quotes} or {open_quotes}Pink{close_quotes} reservoir, Prospect Mars, Mississippi Canyon Areas 763 and 807, Gulf of Mexico. Reservoir compartmentalization is influenced by stratigraphic shingling, which in turn is caused by low accommodation space predentin the upper portion of a ponded seismic sequence within a salt withdrawal mini-basin.more » The accumulation is limited by updip onlap onto a condensed section marl, and by lateral truncation by a large scale submarine erosion surface. Compartments were suggested by RFT pressure variations and by geochemical analysis of RFT fluid samples. A geological interpretation derived from high-resolution 3-D seismic and three wells was linked to 3-D architecture models through seismic inversion, resulting in a reservoir all available data. Distinguishing subtle stratigraphical shingles from faults was accomplished by detailed, loop-level mapping, and was important to characterize the different types of reservoir compartments. Seismic inversion was used to detune the seismic amplitude, adjust sandbody thickness, and update the rock properties. Recent development wells confirm the architectural style identified. This modeling project illustrates how high-quality seismic data and architecture models can be combined in a pre-development phase of a prospect, in order to optimize well placement.« less

3D architecture modeling of reservoir compartments in a Shingled Turbidite Reservoir using high-resolution seismic data and sparse well control, example from Mars [open quotes]Pink[close quotes] reservoir, Mississippi Canyon Area, Gulf of Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chapin, M.A.; Mahaffie, M.J.; Tiller, G.M.

1996-01-01

Economics of most deep-water development projects require large reservoir volumes to be drained with relatively few wells. The presence of reservoir compartments must therefore be detected and planned for in a pre-development stage. We have used 3-D seismic data to constrain large-scale, deterministic reservoir bodies in a 3-D architecture model of Pliocene-turbidite sands of the [open quotes]E[close quotes] or [open quotes]Pink[close quotes] reservoir, Prospect Mars, Mississippi Canyon Areas 763 and 807, Gulf of Mexico. Reservoir compartmentalization is influenced by stratigraphic shingling, which in turn is caused by low accommodation space predentin the upper portion of a ponded seismic sequence withinmore » a salt withdrawal mini-basin. The accumulation is limited by updip onlap onto a condensed section marl, and by lateral truncation by a large scale submarine erosion surface. Compartments were suggested by RFT pressure variations and by geochemical analysis of RFT fluid samples. A geological interpretation derived from high-resolution 3-D seismic and three wells was linked to 3-D architecture models through seismic inversion, resulting in a reservoir all available data. Distinguishing subtle stratigraphical shingles from faults was accomplished by detailed, loop-level mapping, and was important to characterize the different types of reservoir compartments. Seismic inversion was used to detune the seismic amplitude, adjust sandbody thickness, and update the rock properties. Recent development wells confirm the architectural style identified. This modeling project illustrates how high-quality seismic data and architecture models can be combined in a pre-development phase of a prospect, in order to optimize well placement.« less

Use of geostatistic techniques to describe a reservoir to be submitted into a secondary recovery process field case: {open_quotes}Eocene B-Inferior/VLG-3659, Ceuta, Venezuela{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hernandez, T.; Poquioma, W.

1997-08-01

This study presents the results of an integrated reservoir study of the Eocene B-Inferior/VLG-3659, Area 7, Ceuta filed. This field located in the Maracaibo Lake in the western side of Venezuela. The objective was to evaluating the feasibility to implement a secondary recovery project by means of water flooding. Core information was used for this study (194 ft), PVT analysis, RFI, build-up and statistic`s pressure analysis, modem logs and production history data. Using geostatistical techniques (Kriging) it was defined a low uncertainty geological model that was validated by means of a black oil simulator (Eclipse). The results showed a goodmore » comparison of historical pressure of the reservoir against those obtained from the model, without the need of {open_quotes}history matching{close_quotes}. It means without modifying neither the initial rock properties nor reservoir fluids. The results of this study recommended drilling in two new locations, also the reactivation of four producing wells and water flooding under peripherical array by means of four injection wells, with the recovery of an additional 30.2 MMSTB. The economical evaluation shows an internal return rate of 31.4%.« less

The quantum defect: Early history and recent developments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rau, A.R.; Inokuti, M.

1997-03-01

The notion of the quantum defect is important in atomic and molecular spectroscopy and also in unifying spectroscopy with collision theory. In the latter context, the quantum defect may be viewed as an ancestor of the phase shift. However, the origin of the term {open_quotes}quantum defect{close_quotes} does not seem to be explained in standard textbooks. It occurred in a 1921 paper by Schr{umlt o}dinger, preceding quantum mechanics, yet giving the correct meaning as an index of the short-range interactions with the core of an atom. We present the early history of the quantum-defect idea, and sketch its recent developments. {copyright}more » {ital 1997 American Association of Physics Teachers.}« less

Revisiting Neil Armstrongs Moon-Landing Quote: Implications for Speech Perception, Function Word Reduction, and Acoustic Ambiguity

PubMed Central

Baese-Berk, Melissa M.; Dilley, Laura C.; Schmidt, Stephanie; Morrill, Tuuli H.; Pitt, Mark A.

2016-01-01

Neil Armstrong insisted that his quote upon landing on the moon was misheard, and that he had said one small step for a man, instead of one small step for man. What he said is unclear in part because function words like a can be reduced and spectrally indistinguishable from the preceding context. Therefore, their presence can be ambiguous, and they may disappear perceptually depending on the rate of surrounding speech. Two experiments are presented examining production and perception of reduced tokens of for and for a in spontaneous speech. Experiment 1 investigates the distributions of several acoustic features of for and for a. The results suggest that the distributions of for and for a overlap substantially, both in terms of temporal and spectral characteristics. Experiment 2 examines perception of these same tokens when the context speaking rate differs. The perceptibility of the function word a varies as a function of this context speaking rate. These results demonstrate that substantial ambiguity exists in the original quote from Armstrong, and that this ambiguity may be understood through context speaking rate. PMID:27603209

Revisiting Neil Armstrongs Moon-Landing Quote: Implications for Speech Perception, Function Word Reduction, and Acoustic Ambiguity.

PubMed

Baese-Berk, Melissa M; Dilley, Laura C; Schmidt, Stephanie; Morrill, Tuuli H; Pitt, Mark A

2016-01-01

Neil Armstrong insisted that his quote upon landing on the moon was misheard, and that he had said one small step for a man, instead of one small step for man. What he said is unclear in part because function words like a can be reduced and spectrally indistinguishable from the preceding context. Therefore, their presence can be ambiguous, and they may disappear perceptually depending on the rate of surrounding speech. Two experiments are presented examining production and perception of reduced tokens of for and for a in spontaneous speech. Experiment 1 investigates the distributions of several acoustic features of for and for a. The results suggest that the distributions of for and for a overlap substantially, both in terms of temporal and spectral characteristics. Experiment 2 examines perception of these same tokens when the context speaking rate differs. The perceptibility of the function word a varies as a function of this context speaking rate. These results demonstrate that substantial ambiguity exists in the original quote from Armstrong, and that this ambiguity may be understood through context speaking rate.

Words of Wisdom from the Literacy Symposium (Washington, D.C., May 25, 1988). Quotes from Participants and Attendees.

ERIC Educational Resources Information Center

Potter, Charles, Comp.

Materials from the Literacy Symposium that begin this document are a letter of support from Barbara Bush, a symposium agenda, and lists of panel participants, speakers, symposium staff, and members of the Academic Advisory Council to the U.S. Government Printing Office. These are followed by 21 pages of quotes from particpants. Those quoted…

[Research on medical works of Yuan dynasty quoted by Yong le da dian (The Great classic of Yongle reign)].

PubMed

Du, Yong

2003-01-01

The medical works quoted by Yong le da dian (The Great Classic of Yongle reign) are rather numerous, most of them were lost, and the lives of most of the authors were unknown. By careful investigation, the authors and their lives, circulation of these works, are still pursuable.

Hamiltonian structure of Dubrovin{close_quote}s equation of associativity in 2-d topological field theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galvao, C.A.; Nutku, Y.

1996-12-01

mA third order Monge-Amp{grave e}re type equation of associativity that Dubrovin has obtained in 2-d topological field theory is formulated in terms of a variational principle subject to second class constraints. Using Dirac{close_quote}s theory of constraints this degenerate Lagrangian system is cast into Hamiltonian form and the Hamiltonian operator is obtained from the Dirac bracket. There is a new type of Kac-Moody algebra that corresponds to this Hamiltonian operator. In particular, it is not a W-algebra. {copyright} {ital 1996 American Institute of Physics.}

Characteristic time scales of tick quotes on foreign currency markets: an empirical study and agent-based model

NASA Astrophysics Data System (ADS)

Sato, A.-H.

2006-03-01

Power spectrum densities for the number of tick quotes per minute (market activity) on three currency markets (USD/JPY, EUR/USD, and JPY/EUR) for periods from January 1999 to December 2000 are analyzed. We find some peaks on the power spectrum densities at a few minutes. We develop the double-threshold agent model and confirm that stochastic resonance occurs for the market activity of this model. We propose a hypothesis that the periodicities found on the power spectrum densities can be observed due to stochastic resonance.

Early parental adjustment and bereavement after childhood cancer death.

PubMed

Barrera, Maru; O'Connor, Kathleen; D'Agostino, Norma Mammone; Spencer, Lynlee; Nicholas, David; Jovcevska, Vesna; Tallet, Susan; Schneiderman, Gerald

2009-07-01

This study comprehensively explored parental bereavement and adjustment at 6 months post-loss due to childhood cancer. Interviews were conducted with 18 mothers and 13 fathers. Interviews were transcribed verbatim and analyzed based on qualitative methodology. A model describing early parental bereavement and adaptation emerged with 3 domains: (1) Perception of the Child, describing bereavement and adjustment prior to and after the loss; (2) Perception of Others, including relationships with partners, surviving children, and their social network; and (3) Perception of the World, exploring parents' perceived meanings of the experience in the context of their worldview. Domains are illustrated by quotes. Profiles of parental bereavement emerged.

46 CFR Exhibit No. 1 to Subpart Q... - Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 9 2012-10-01 2012-10-01 false Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error No. Exhibit No. 1 to Subpart Q [§ 502.271(d)] of Part 502 Shipping... or Waiver of Freight Charges Pt. 502, Subpt. Q, Exh. 1 Exhibit No. 1 to Subpart Q [§ 502.271(d)] of...

46 CFR Exhibit No. 1 to Subpart Q... - Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 9 2013-10-01 2013-10-01 false Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error No. Exhibit No. 1 to Subpart Q [§ 502.271(d)] of Part 502 Shipping... or Waiver of Freight Charges Pt. 502, Subpt. Q, Exh. 1 Exhibit No. 1 to Subpart Q [§ 502.271(d)] of...

46 CFR Exhibit No. 1 to Subpart Q... - Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 9 2014-10-01 2014-10-01 false Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error No. Exhibit No. 1 to Subpart Q [§ 502.271(d)] of Part 502 Shipping... or Waiver of Freight Charges Pt. 502, Subpt. Q, Exh. 1 Exhibit No. 1 to Subpart Q [§ 502.271(d)] of...

46 CFR Exhibit No. 1 to Subpart Q... - Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 9 2010-10-01 2010-10-01 false Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error No. Exhibit No. 1 to Subpart Q [§ 502.271(d)] of Part 502 Shipping... or Waiver of Freight Charges Pt. 502, Subpt. Q, Exh. 1 Exhibit No. 1 to Subpart Q [§ 502.271(d)] of...

46 CFR Exhibit No. 1 to Subpart Q... - Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 9 2011-10-01 2011-10-01 false Application for Refund or Waiver of Freight Charges Due to Tariff or Quoting Error No. Exhibit No. 1 to Subpart Q [§ 502.271(d)] of Part 502 Shipping... or Waiver of Freight Charges Pt. 502, Subpt. Q, Exh. 1 Exhibit No. 1 to Subpart Q [§ 502.271(d)] of...

A new structure related to the layered cuprates: The {open_quotes}1201{angstrom} shear-like phase Tl{sub 5}Ba{sub 3}Sr{sub 5}Cu{sub 3}O{sub 19}, third member of the series (TlA{sub 2}CuO{sub 5}){sub m}{center_dot}Tl{sub 2}A{sub 2}O{sub 4}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Letouze, F.; Martin, C.; Hervieu, M.

1997-01-01

A thallium cuprate, Tl{sub 5}Ba{sub 3}Sr{sub 5}Cu{sub 3}O{sub 19}, whose structure can be derived by systematically shearing the {open_quotes}1201{close_quotes} structure has been synthesized for the first time. It crystallizes in an orthorhombic cell with a=3.7536(2) {angstrom}, b=30.631(2) {angstrom}, c=9.219(1) {angstrom}, and A-type symmetry. This new structure consists of {open_quotes}1201{close_quotes} ribbons parallel to (010) which are three CuO{sub 6} octahedra wide and are interconnected through {open_quotes}Tl{sub 2}A{sub 2}O{sub 4}{close_quotes} ribbons whose cationic configuration is that of the rock salt structure. This phase can be considered to be the m = 3 member of a new series with the generic formulation (TlA{submore » 2}CuO{sub 5}){sub m} {center_dot} Tl{sub 2}A{sub 2}O{sub 4} with A = Ba, Sr.« less

Comment on {open_quote}{open_quote}Electronic model for superconductivity{close_quote}{close_quote}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Angelucci, A.; Sorella, S.

1996-05-01

A Comment on the Letter by Fabian H.L. Essler, Vladimir E. Korepin, and Kareljan Schoutens, Phys.Rev.Lett.{bold 70}, 73 (1993). The authors of the Letter offer a Reply. {copyright} {ital 1996 The American Physical Society.}

[Echographic diagnosis of missed early miscarriage: Assessment of image quality].

PubMed

Barthes, C; Mezan De Malartic, C; Baumann, C; Rousseaux, H; Morel, O

2018-02-01

Ultrasound examination plays a central role in case of suspected non-viable pregnancy. A wrong diagnosis might have major consequence in terms of inadequate care, especially in cases of false positive non-viable pregnancy diagnosis. Ultrasound criterions are today well defined. Our objective was to evaluate the feasibility and reproducibility of a novel image-quoting method of first-trimester non-viable pregnancy. Thirty images of non-viable pregnancy were twice evaluated with blinded proofreading. Two quotations were evaluated: the first for the images of gestational sacs without embryo (gestational sac score), the second for the images with embryo (embryo score). The ICC (interclass correlation coefficient) was>0.75 for inter- and intra-observer reproducibility both for the quotations of the gestational sac and for the embryo with a low variability. Reproducibility of quoting crown rump length measurements <5mm was low at first proofreading but after adjustment of the quoting modalities, ICC was also>0.75. The inter- and intra-observer reproducibility of our quoting methods is high with a low variability. They might be a useful tool in current practice in the future. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

BIG KARL and COSY: Examples for high performance magnet design taught by {open_quotes}Papa Klaus{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bechtstedt, U.; Hacker, U.; Maier, R.

1995-02-01

The past decades have seen a tremendous development in nuclear, middle, and high energy physics. This advance was in a great part promoted by the availability of newer and more powerful instruments. Over time, these instruments grew in size as well as in sophistication and precision. Nearly all these devices had one fundamental thing in common - magnetic fields produced with currents and iron. The precision demanded by the new experiments and machines did bring the magnet technology to new frontiers requiring the utmost in the accuracy of magnetic fields. The complex properties of the iron challenged innumerable physicists inmore » the attempt to force the magnetic fields into the desired shape. Experience and analytical insight were the pillars for coping with those problems and only few mastered the skills and were in addition able to communicate their intricate knowledge. It was a fortuitous situation that the authors got to know Klaus Halbach who belonged to those few and who shared his knowledge contributing thus largely to the successful completion of two large instruments that were built at the Forschungszentrum Juelich, KFA, for nuclear and middle energy physics. In one case the efforts went to the large spectrometer named BIG KARL whose design phase started in the early 70`s. In the second case the work started in the early 80`s with the task to build a high precision 2.5 GeV proton accelerator for cooled stored and extracted beams known as COSY-Juelich.« less

Resilience as resistance to the new managerialism: portraits that reframe nursing through quotes from the field.

PubMed

Cope, Vicki; Jones, Bronwyn; Hendricks, Joyce

2016-01-01

This paper acknowledges the relationship between resilience and the new managerialism of contemporary nursing. Qualitative portraiture methodology. The new managerialism in hospital settings results in a rapidly increasing turnover of acutely ill or comorbid patients, which directly relates to retention and quality service. In education settings, the management imperative to recruit more students into the profession combined with financial cutbacks leads to similar tensions. In aged care the trend equates care directly with funding, with the same effect. Yet despite this, many registered nurses remain working. Portraiture explored 'why' nurses remain in workplaces often described as awful. The resilience of nurses is seen through their stories and reframed to highlight resilience as a form of resistance to the new managerialism inherent in contemporary healthcare. This paper describes some of the hallmarks of new managerialism where workforce pressures force practices that do not value the 'human resource'. The quotes from the field give insight into the nurse's world view and have implications for managers, educators and employers, as well as for consumers of nursing care. © 2015 John Wiley & Sons Ltd.

Knowledge of the anatomy and physiology of the spleen throughout Antiquity and the Early Middle Ages.

PubMed

Paraskevas, George K; Koutsouflianiotis, Konstantinos N; Nitsa, Zoi; Demesticha, Theano; Skandalakis, Panagiotis

2016-01-01

The evolution of knowledge regarding the anatomy and physiology of the spleen throughout Antiquity and the Early Middle Ages is described, and general perceptions about this organ during different eras along this time line are presented. The original words of great physicians from the period of time stretching from Ancient Egypt to the Avicennan era are quoted and discussed to demonstrate how knowledge of the spleen has evolved and to present the theories that dominated each era. Furthermore, theories about illnesses relating to the spleen are reported, which show how this organ was perceived-in terms of its function and anatomy-during each era.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geltman, S.

Recent measurements on CO{sub 2}-laser-assisted electron-atom collisions have shown large inconsistencies with the Kroll-Watson formula for small-angle scattering. We have carried out a detailed study to compare the predictions of Kroll-Watson theory (for both single and multimode fields) with those of conventional perturbation theory for stimulated free-free transitions. It is found that for {ital E}{sub 0}/2{omega}{sup 2}{lt}1, where perturbation theory is valid, there are large differences with the Kroll-Watson theory. Comparisons of experimental variations with respect to scattering angle and electron energy show much better agreement with perturbation theory than with Kroll-Watson theory. A study of the angular variations inmore » perturbation theory shows that use of the {open_quote}{open_quote}outgoing{close_quote}{close_quote} wave final state gives much better agreement with experiment than does the {open_quote}{open_quote}ingoing{close_quote}{close_quote} wave final state, which is different from the choice made in early bremsstrahlung theory. {copyright} {ital 1996 The American Physical Society.}« less

A population-based study of familial Alzheimer disease: Linkage to chromosomes 14, 19, and 21

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duijn, C.M. van; Hofman, A.; Hendriks, L.

1994-10-01

Linkage of Alzheimer disease (AD) to DNA markers on chromosomes 14, 19, and 21 was studied in 10 families in which the disease was apparently inherited as an autosomal dominant trait. Families were derived from a Dutch population-based epidemiologic study of early-onset AD. Although in all probands the onset of AD was at or before age 65 years, the mean age at onset was after age 65 years in four families (referred to as {open_quotes}LOAD{close_quotes}). Among the six families with early-onset AD (referred to as {open_quotes}EOAD,{close_quotes} i.e., mean age of onset of AD of relatives was at or before agemore » 65 years), conclusive linkage to 14q24.3 was found in one family with a very early onset (around 47 years), while linkage to the same region was excluded in two other families. For the LOAD families, predominantly negative lod scores were obtained, and the overall lod score excluded linkage to chromosome 14. The results with markers on chromosome 19 and chromosome 21 were not conclusive for EOAD and LOAD. The findings of our study confirm genetic heterogeneity within familial EOAD. 50 refs., 7 figs., 2 tabs.« less

Program for training a measurement technician

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gates, A.L.

In the early 1970`s when the price of gas went from an average of 17 cents per thousand cubic feet tomore » $$2.00 and the words {open_quote}take or pay{close_quote} became prevalent, many companies started thinking about advanced training programs. Many organizations, such as ours, had basically used the {open_quotes}hands on or the on the job training approach.{close_quote} Utilization of these methods often fostered bad habits, as well as, a lack of standardization in our organization. Additional price increases for gas became the standard until the bottom fell out of the oil patch around 1983. Other factors in the early 1980`s generated the need for greater training efforts that have not slowed down as of yet, and the greatest factor has been technology. Remote terminal units, flow computers, transducers, analog 10`s, audit trails, MMBTU`s, real time measurement, Therm Titrators and Danalizers are just a few of the terms or items that we started utilizing in the early eighties that we now generally accept in our day to day activities. However; as we have moved through these stages, there appears to be even a greater sense of urgency to become better trained. Gas prices are now less than $$1.00 per thousand. Open access moves greater volumes with considerably less margins just so we can get in on the action. These new measuring stations at transportation connects have reached complexities never imagined before requiring measurement technicians to posses knowledge and skills that simply cannot be acceptable as {open_quote}getting by.{close_quote} The smallest errors can mean losses in the thousands of dollars each day if not corrected, and they are totally unacceptable by those we do business with in a complex industry as ours today. In periods such as the gas industry is facing today, it is easy to enter periods of austerity, make budget cuts and generally reduce effective training programs.« less

Stacking pattern and stratigraphic model of reservoirs from a modern analogue to ancient deltaic and siliciclastic deposits: Golfe du Lion, SE France

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tesson, M.; Bernard, G.; Georges, A.

1995-08-01

The {open_quotes}Golfe du Lion{close_quotes} Pleistocene shelf deposits are used as modern analogues of ancient deltaic and shallow water siliciclastic deposits. At least 6 cyclic superimposed sedimentary packages constituting a seaward thickening wedge are documented, including major progradational clinoforms units bounded by regional unconformities, with their updip terminations. Seismic correlations and geometry models, together with age dating and facies analysis of the uppermost units have been used at regional scale. They allowed to differentiate allocyclic from autocyclic events, to improve our knowledge of the nature of tectonic control on architecture, and to rely the different seismic units, inside the packages, tomore » the environmental changes from interglacial highstand to glacial lowstand in 4 to 5th order cycles. An alternative model of {open_quotes}forced regression{close_quotes} during sea level lowstand was documented and validated. The different illustrated sedimentary units, related to specific parts of the relative sea level curve along a short duration/high amplitude cycle, are: (i) the {open_quotes}forced regression{close_quotes} deposits (ii) the late lowstand massive sands onto the outer shelf (iii) the early transgressive backstepping (?) beach sands, (iii) the late transgressive backslapping parasequences. The sand content inferred from the seismic facies, comforted with the uppermost units facies from data cores, is in agreement with this model.« less

Ecosystem behavior at Bermuda Station [open quotes]S[close quotes] and ocean weather station [open quotes]India[close quotes]: A general circulation model and observational analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fasham, M.J.R.; Sarmiento, J.L.; Slater, R.D.

1993-06-01

One important theme of modern biological oceanography has been the attempt to develop models of how the marine ecosystem responds to variations in the physical forcing functions such as solar radiation and the wind field. The authors have addressed the problem by embedding simple ecosystem models into a seasonally forced three-dimensional general circulation model of the North Atlantic ocean. In this paper first, some of the underlying biological assumptions of the ecosystem model are presented, followed by an analysis of how well the model predicts the seasonal cycle of the biological variables at Bermuda Station s' and Ocean Weather Stationmore » India. The model gives a good overall fit to the observations but does not faithfully model the whole seasonal ecosystem model. 57 refs., 25 figs., 5 tabs.« less

Famous endoscopy quotes.

PubMed

Cappell, Mitchell S

2012-01-01

These quotations, whether humorous or serious, provide insight into how gastroenterology nurses, gastroenterologists, and endoscopists feel about themselves as professionals, how other healthcare professionals perceive them, and their image in popular culture. Recognition of these aspects of gastroenterology nursing, gastroenterology, and endoscopy are important for self-improvement, correcting public misperceptions, and appreciating how patient misperceptions about gastroenterology nurses and gastroenterologists and patient attitudes toward endoscopy may present barriers that gastroenterology professionals must overcome to improve patient care. These quotations also fulfill a need for witticisms during dry endoscopy lectures!

Quotes on Caring

ERIC Educational Resources Information Center

Knowledge Quest, 2012

2012-01-01

In this article, school librarians from Henrico County Public Schools in Virginia [the AASL 2011 National School Library Programs of the Year (NSLPY) Award recipient] share some of their experiences caring for students in their libraries.

Large area multiarc ion beam source {open_quote}MAIS{close_quote}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engelko, V.; Giese, H.; Schalk, S.

1996-12-31

A pulsed large area intense ion beam source is described, in which the ion emitting plasma is built up by an array of individual discharge units, homogeneously distributed over the surface of a common discharge electrode. A particularly advantageous feature of the source is that for plasma generation and subsequent acceleration of the ions only one common energy supply is necessary. This allows to simplify the source design and provides inherent synchronization of plasma production and ion extraction. The homogeneity of the plasma density was found to be superior to plasma sources using plasma expanders. Originally conceived for the productionmore » of proton beams, the source can easily be modified for the production of beams composed of carbon and metal ions or mixed ion species. Results of investigations of the source performance for the production of a proton beam are presented. The maximum beam current achieved to date is of the order of 100 A, with a particle kinetic energy of 15 - 30 keV and a pulse length in the range of 10 {mu}s.« less

Evidence found for a possible [open quote]aggression gene[close quote

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morell, V.

1993-06-18

Researchers in the Netherlands are on the track of a genetic mutation in a large Dutch family that may cause periodic outbursts of aggression in its possessors. Han G. Brunner and his colleagues at Univ. Hospital in Nijmegen report evidence suggesting that a mutation in the gene for monoamine oxidase A (MAOA) may underlie the aggressive and sometimes violent behavior displayed by certain males in this family. A linkage between MAOA gene defect and behavioral problems would make biological sense because the enzyme encoded by the gene helps break down several neurotransmitters that might, if their concentrations build up abnormally,more » cause a person to respond excessively-and at times even violently-to stress. If this original report is borne out by further work, it would be the first time that a specific gene defect has been found to predispose its bearers to aggressive behavior. Using markers for the X chromosome, Brunner and his colleagues identified the MAO gene region as the likely site for the diseased gene.« less

Kauai Test Facility hazards assessment document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swihart, A

1995-05-01

The Department of Energy Order 55003A requires facility-specific hazards assessment be prepared, maintained, and used for emergency planning purposes. This hazards assessment document describes the chemical and radiological hazards associated with the Kauai Test Facility, Barking Sands, Kauai, Hawaii. The Kauai Test Facility`s chemical and radiological inventories were screened according to potential airborne impact to onsite and offsite individuals. The air dispersion model, ALOHA, estimated pollutant concentrations downwind from the source of a release, taking into consideration the toxicological and physical characteristics of the release site, the atmospheric conditions, and the circumstances of the release. The greatest distance to themore » Early Severe Health Effects threshold is 4.2 kilometers. The highest emergency classification is a General Emergency at the {open_quotes}Main Complex{close_quotes} and a Site Area Emergency at the Kokole Point Launch Site. The Emergency Planning Zone for the {open_quotes}Main Complex{close_quotes} is 5 kilometers. The Emergency Planning Zone for the Kokole Point Launch Site is the Pacific Missile Range Facility`s site boundary.« less

Flank eruptions of Mt Etna during the Greek-Roman and Early Medieval periods: New data from 226Ra-230Th dating and archaeomagnetism

NASA Astrophysics Data System (ADS)

Branca, Stefano; Condomines, Michel; Tanguy, Jean-Claude

2015-10-01

In this paper, we present new data from 226Ra-230Th dating and archaeomagnetism with the aim of improving the knowledge of the flank eruptions that occurred at Mt Etna during the Greek-Roman and Early Medieval periods, as defined in the new geological map of the volcano. The combination of the two dating techniques demonstrates that three major flank eruptions occurred on the lower north and west flanks during Greek-Roman epochs, producing large scoria cones and extensive lava flows. In particular, the Mt Ruvolo and Mt Minardo events highly impacted the territory of the west flank, notably by damming the Simeto River. The new data of the Millicucco and Due Monti lava flows, on the lower north-east flank, indicate a younger age than their stratigraphic ages quoted in the 2011 geological map, since they occurred around 700 and 500 AD, respectively. None of the large flank eruptions occurring on the lower slopes of Etna during the Early Medieval age are reported in the historical sources. Overall, our paper shows that a comprehensive assessment of eruptions at Mount Etna in the last three millennia can only be achieved through a multidisciplinary approach.

Answer to Question {number_sign}21 [{open_quote}{open_quote}Snell{close_quote}s law in quantum mechanics,{close_quote}{close_quote} Steve Blau and Brad Halfpap, Am. J. Phys. {bold 63} (7), 583 (1995)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milonni, P.W.

1996-07-01

The quantum mechanical description of reflection and refraction in terms of photons is further extrapolated. The probability amplitude for a photon to be found inside or outside the medium is derived.

Upper cretaceous (Austin Group) volcanic deposits as a hydrocarbon trap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hutchinson, P.J.

1994-12-31

An Upper Cretaceous submarine igneous extrusion occurs in the subsurface of southwestern Wilson County, Texas. The Coniacian-Santonian-aged (Austin Group) volcanic eruption discharged large volumes of magnetite-rich olivine nephelinite that upon quenching formed an extensive nontronitic clay layer. This clay deposit formed a trapping mechanism for hydrocarbon beneath the volcano. Production from volcanic plugs is normally attributed to the shoal-water carbonate facies developed on top of the volcanic, the palagonite tuff ({open_quotes}serpentine{close_quotes}), and overlying sandstones. The heat energy of the volcano may have thermally matured the calcarous sediments of adjacent parts of the Austin Chalk. The normally grayish-colored suggesting thermal alteration.more » The overlying nontronite trapped mobile hydrocarbons, and this early emplacement of oil may have preserved some of the original porosity and permeability of the Austin Chalk. Austin Chalk-aged volcanic deposits produce hydrocarbons from stratigraphic traps within the volcanic material, within the porous beachrock, and structurally within overlying sandstones. The intruded Austin Chalk also behaves as a reservoir because the original porosity and permeability are maintained by early emplacement of oil and the overlying volcanic clay acts as a seal by preventing vertical migration. Marcelina Creek field, discovered in 1980 from an {open_quotes}augen{close_quotes}-shaped seismic signature and an aerial magnetic survey, produces from the fractured chalk beneath the nontronitic clay layer. This field has produced more than 15 million barrels of oil from more than 60 wells in fractured and porous rock beneath the volcano.« less

Truth was an early casualty

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sich, A.R.

1996-05-01

At a May 1986 press conference in Moscow-held just 11 days after the accident at the Chernobyl Nuclear Power Station-the cult of high technology was unabashedly preached to an auditorium full of shocked news correspondents and invited guests. When questioned as to the number of fatalities the accident had caused and the impact of the accident on Soviet society and the Soviet nuclear industry, A.M. Petrosyants (then chairman of the Soviet State Committee on the Utilization of Atomic Energy) responded: {open_quotes}Science requires victims.{close_quotes} The Soviet system numbered its victims in the millions. In a sense, the Chernobyl accident was justmore » one of the many misfortunes misrepresented by the Soviet government over the decades in its continuing effort to shape public perceptions of domestic disasters, natural and manmade. And yet, the international character of the Chernobyl accident, the fact that radioactive fallout knows no national boundaries, made it a watershed event. The accident exposed glaring weaknesses in the Soviet system: its backward technology, its sloppy safety standards, its inability to admit failure. And it brought to the surface many of the injustices, inefficiencies, and secrets that the Soviet government had tried to keep hidden. With the world`s spotlight focused on Chernobyl, General Secretary Mikhail Gorbachev was left with little choice other than to prove to the West his dedication to reform by more fully implementing his recently announced policy of glasnost or `openness.` In turn, glasnost was a major factor that led to the demise of the Soviet Union, which embodied a system that was fundamentally at odds with freedom of expression and accessibile information. Unfortunately, old habits die hard. Ten years after the accident, many nuclear bureaucrats in the former Soviet Union, partiularly in Russia, are still too secretive and too much given to obfuscation.« less

Efficient runner safety assessment during early design phase and root cause analysis

NASA Astrophysics Data System (ADS)

Liang, Q. W.; Lais, S.; Gentner, C.; Braun, O.

2012-11-01

Fatigue related problems in Francis turbines, especially high head Francis turbines, have been published several times in the last years. During operation the runner is exposed to various steady and unsteady hydraulic loads. Therefore the analysis of forced response of the runner structure requires a combined approach of fluid dynamics and structural dynamics. Due to the high complexity of the phenomena and due to the limitation of computer power, the numerical prediction was in the past too expensive and not feasible for the use as standard design tool. However, due to continuous improvement of the knowledge and the simulation tools such complex analysis has become part of the design procedure in ANDRITZ HYDRO. This article describes the application of most advanced analysis techniques in runner safety check (RSC), including steady state CFD analysis, transient CFD analysis considering rotor stator interaction (RSI), static FE analysis and modal analysis in water considering the added mass effect, in the early design phase. This procedure allows a very efficient interaction between the hydraulic designer and the mechanical designer during the design phase, such that a risk of failure can be detected and avoided in an early design stage.The RSC procedure can also be applied to a root cause analysis (RCA) both to find out the cause of failure and to quickly define a technical solution to meet the safety criteria. An efficient application to a RCA of cracks in a Francis runner is quoted in this article as an example. The results of the RCA are presented together with an efficient and inexpensive solution whose effectiveness could be proven again by applying the described RSC technics. It is shown that, with the RSC procedure developed and applied as standard procedure in ANDRITZ HYDRO such a failure is excluded in an early design phase. Moreover, the RSC procedure is compatible with different commercial and open source codes and can be easily adapted to apply for

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walker, R.B.; Gessel, S.P.; Held, E.E.

During the 1950`s and 1960`s, the Laboratory of Radiation Biology at the University of Washington carried out an intensive study of this Atoll, which was contaminated with radioactive fallout from the {open_quotes}Bravo shot{close_quotes} in 1954. This study involved many aspects of the environment and the plant and animal life: soils, land plants, marine life, birds, geology and hydrology, and human diets as well. In much of the research, the fortuitiously present radioactive isotopes, especially {sup 137}Cs and {sup 90}Sr, were tracers. Although the term {open_quotes}ecosystem study{close_quotes} was not in vogue at that time, it is clear that this was anmore » early use of the ecosystem approach. Soil types and their development, the distribution of mineral elements in plants and soils, including predominant radionuclides, distribution and growth of native terrestrial plants in relation to topography and salinity, some aspects of the human diets, micronutrient nutrition of the coconut palm, island and islet development and stability, were given attention in the studies. Some of the findings in the various areas of study will be presented and discussed. 32 refs., 2 figs., 8 tabs.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elias, D.F.; Corbin, W.E.

Mercury, or quicksilver, and its major ore cinnabar (HgS) have been known for thousands of years. Health effects from mercury such as dementia were known as early as the late 19th century ({open_quotes}mad as a hatter{close_quotes}). In the 1960`s and 1970`s, reported levels of mercury in tuna reawakened public awareness of mercury pollution. In the 1970`s, major epidemics of acute mercury poisoning were reported in Japan and Iraq. These incidents highlighted the extreme health risks, such as kidney damage, birth defects, and death, associated with severe mercury poisoning. Fetuses and young children are particularly vulnerable since mercury poisoning can damagemore » growing neural tissues. Recently, the perception of mercury as a dangerous pollutant has been on the rise. Advisories warning the public to avoid or reduce the consumption of freshwater fish caught in specific waterbodies due to mercury contamination have been issued in numerous states. The discovery of mercury in {open_quotes}pristine{close_quotes} lakes in the United States, Canada, and Scandinavia, remote from industry and any known mercury sources, has focused attention on atmospheric emissions of mercury as potential significant sources of mercury.« less

Answer to Question {number_sign}30 [{open_quote}{open_quote}How are positrons moderated?,{close_quote}{close_quote} Thomas D. Rossing, Am. J. Phys. {bold 63}(12), 1065 (1995)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weber, M.; Lynn, K.G.

1996-07-01

The positrons from {beta}{sup +} decaying sources loss energyat a much faster rate than they annihilate. As the energy of the positrons drops, core excitations, plasmon excitation, electron/hole pair creation, and phonon scattering are the dominant processes of further energy loss.

[Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

PubMed

Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

2014-05-01

Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

Numerical methods for the unsymmetric tridiagonal eigenvalue problem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jessup, E.R.

1996-12-31

This report summarizes the results of our project {open_quotes}Numerical Methods for the Unsymmetric Tridiagonal Eigenvalue Problem{close_quotes}. It was funded by both by a DOE grant (No. DE-FG02-92ER25122, 6/1/92-5/31/94, $100,000) and by an NSF Research Initiation Award (No. CCR-9109785, 7/1/91-6/30/93, $46,564.) The publications resulting from that project during the DOE funding period are listed below. Two other journal papers and two other conference papers were produced during the NSF funding period. Most of the listed conference papers are early or partial versions of the listed journal papers.

Quotable Quotes in Mathematics

ERIC Educational Resources Information Center

Lo, Bruce W. N.

1983-01-01

As a way to dispel negative feelings toward mathematics, a variety of quotations are given. They are categorized by: what mathematics is, mathematicians, mathematics and other disciplines, different areas of mathematics, mathematics and humor, applications of mathematics, and pure versus applied mathematics. (MNS)

Oil geochemistry of the northern Llanos Basin, Colombia. A model for migration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramon, J.C.; Dzou, L.

1996-12-31

The chemical composition of 23 crude oils and one oil seep from Llanos Basin, Colombia were studied in detail by geochemical methods in order to understand their genetic relationship. A filling history model is proposed to explain the observed composition variations in Llanos Basin oils. Geochemical fingerprinting indicates that there are six families of crude oils. The biomarker compositions have been used to identify characteristics of the source rocks. The Llanos oils contain marine algal- derived {open_quotes}C30 steranes{close_quotes} (i.e., 24-n-propylcholestanes), which are diagnostic for oils generated from marine Cretaceous source rocks. A significant HC-contribution from a Tertiary source is alsomore » indicated by the presence of high concentration of the {open_quotes}flowering plant{close_quotes}-markers oleanane, bicadinanes and oleanoids. Low DBT/Phen, %sulfur values and high diasteranes concentration indicate that the source rock is clay-rich. Biomarker maturity parameters indicate a wide range of source-rock thermal maturities from early to late oil window. Heavy biodegradation has been particularly common among the first oils to fill reservoirs in central Llanos oil fields. The older altered heavy oils were mixed with a second pulse of oil explaining the wide range of oil gravities measured in the central Llanos Basin.« less

Why bankers force feed the coal market: Differential economics among fuels, between coals, and within coal blends make coal forecasting a very hazardous profession indeed

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tinsley, C.R.

1993-07-01

When bankers try to assess which natural resources are [open quote]safe[close quote] lending targets for project financing, market risk-especially price volatility-is the primary concern. However, coal appears to provide the ingredients to lower this risk perception, namely: stable prices; ability to get long-term [open quotes]contracts[close quotes]; economic rent. Value of energy in thermal coal; direct link to GNP (steel) for coking/metallurgical coal; economies of scale-large unit mining operations; established seaborne trade infrastructure; huge reserves; and straightforward design, estimation, feasibility. Eighteen mine project financings in the 1965-1981 period were analyzed and it was found that of the three coal cases examined,more » two had problems. One of these never achieved the designed production level and the other came in three years late and 50% over budget. (Both were in North America). Of the 18 mines, 13 had severe problems. Despite this gloomy picture, no banks have lost money on their project financings since the sponsors gave direct credit support or injected new equity. In spite of this risky profile, banks again became hot-to-trot on project financings in the early 1980s and it is this era when the basket cases examined were financed to development.« less

The {open_quotes}obligation to serve{close_quotes} and a competitive electric industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Colton, R.D.

1997-11-01

This report presents an assessment of what the ``obligation to serve`` might look like in a competitive electric industry. Broadly, this research has three objectives: to define the ``duty to serve`` of a competitive electric industry; to identify those companies to whom that duty applies; and to explain how that duty protects residual classes.

Dual annular rotating [open quotes]windowed[close quotes] nuclear reflector reactor control system

DOEpatents

Jacox, M.G.; Drexler, R.L.; Hunt, R.N.M.; Lake, J.A.

1994-03-29

A nuclear reactor control system is provided in a nuclear reactor having a core operating in the fast neutron energy spectrum where criticality control is achieved by neutron leakage. The control system includes dual annular, rotatable reflector rings. There are two reflector rings: an inner reflector ring and an outer reflector ring. The reflectors are concentrically assembled, surround the reactor core, and each reflector ring includes a plurality of openings. The openings in each ring are capable of being aligned or non-aligned with each other. Independent driving means for each of the annular reflector rings is provided so that reactor criticality can be initiated and controlled by rotation of either reflector ring such that the extent of alignment of the openings in each ring controls the reflection of neutrons from the core. 4 figures.

The new role of HSE in chemical product development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Purinton, R.J. Jr.; Manning, T.S.; Dowell, S.

1996-11-01

Today, Health, Safety, and Environmental issues take a more prominent role than ever before in chemical product development for the global oilfield service industry. Prior to widespread regulatory guidelines, technical problems were solved and well treatment programs were developed using the chemicals which performed the best and were the least expensive for the application. HSE concerns were sometimes addressed from a remedial standpoint, rather than a preventive one throughout the process. With a clearer understanding of the potential impact of chemicals upon people and the environment, along with the ever-increasing array of government regulations, service companies are taking a newmore » approach to product development. HSE-related risks and costs are being assessed early and continued throughout chemical development, with both product and treatment process features then designed accordingly. One service company reflects this approach with its {open_quotes}cradle-to-grave{close_quotes} Product Development and Stewardship program. Integral to this program are planned HSE assessments at each step of development, including Feasibility, Lab Development, Field Testing, Manufacturing, and Commercial Field Introduction. These assessments provide the data necessary to {open_quotes}engineer-in{close_quotes} solutions to potential HSE-related problems, produce viable Risk Management Plans, and promote a smoother path to commercialization. This avoids arriving at the commercial launch point with a product which poses unacceptably high personal or environmental risks, may be restricted or banned in key markets, or requires lengthy and expensive government registrations. In order to optimize R&E resources and ensure continuous evaluation, decision points (to continue, modify, or abandon) are built into the process. Early HSE screenings must be accurate but also relatively quick and inexpensive to be meaningful and economical.« less

Dabhol resumes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burr, M.T.

1997-01-01

Shockwaves were felt throughout the global business community when political forces in India stalled out the Dabhol power project. Lenders and investors felt even less secure about the risks involved with developing infrastructure projects in emerging economies, and Dabhol came to symbolize the sinkholes that lie in wait for even the best-devised projects with the strongest sponsors. The project resumed in early December, however, after the Bombay High Court dismissed the only remaining lawsuit filed against Dabhol Power Co. Now, the Dabhol project is set to become an example of how a project can succeed in a big way ifmore » it has developers with integrity, skill, flexibility, and--above all--a great deal of patience. Originally a 695 MW facility, Dabhol was renegotiated so the complex totals 2,450 MW, with one 740 MW phase and another 1,710 MW phase. {open_quotes}The additional capacity allowed us to recover the costs we incurred during cancellation,{close_quotes} says Rebecca Mark, CEO of Enron Development Corp. in Houston, Texas. {open_quotes}We reduced rates for the second phase, and we`ll handle it on a competitive basis when it comes to specifying equipment.{close_quotes} Enron is the lead developer of the project, with an 80 percent equity stake. GE Capital of Stamford, Conn., USA, and Bechtel Enterprises of San Francisco, Calif., each hold a 10 percent share in the project. {open_quotes}The changes in the project have had little effect on the financing arrangements. Additional project costs which resulted from the delays were funded by the equity group, and the debt levels and terms remain consistent with those of the original closing,{close_quotes} says Everett Smith III, executive vice president and director-international, for GE Capital Services Structured Finance Group.« less

Battelle developing reefs to ease habitat losses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-04-01

Artificial reefs may be the answer to solving a worldwide problem of declining fish habitats, or they may only be good for creating fishing spots. Researchers at Battelle's Ocean Sciences Laboratory in Duxbury, Massachusetts, are studying artificial reefs in the Delaware River to determine if they are a solution to habitat losses in estuaries and coastal regions. [open quotes]Right now, we don't know if the fish are using the reefs simply as a grazing land, and then moving on, or if they're using the areas to colonize,[close quotes] said researcher Karen Foster. [open quotes]Ultimately, we hope to find they aremore » colonizing.[close quotes] In 1989, Battelle researchers placed 16 prefabricated concrete reefs 45 feet deep in Delaware Bay. The reefs were placed in clusters of four, and monitoring began the following year. The federal government ordered the reefs placed in the bay as a mitigation technique for fish habitat that was lost when the river was dredged for navigational purposes. Researchers examined the reefs twice last summer. It will take five years, Foster said, before researchers can determine if the reefs are increasing the fish population. Early tests show, however, the populations of mussels, sponges, corals, and anemones increased by up to 150 percent over an area of bay bottom where the reefs were placed. Divers take crustacean samples from the reefs, and fish are caught near the reefs for examination. Researchers dissect the fish stomachs and analyze the contents to determine if they have been feeding at the reefs. [open quotes]If we find blue mussels in the stomach of the fish, that's great because we know that blue mussels are growing on the reef,[close quotes] Foster said.« less

Energy vulnerability relationships

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shaw, B.R.; Boesen, J.L.

The US consumption of crude oil resources has been a steadily growing indicator of the vitality and strength of the US economy. At the same time import diversity has also been a rapidly developing dimension of the import picture. In the early 1970`s, embargoes of crude oil from Organization of Producing and Exporting Countries (OPEC) created economic and political havoc due to a significant lack of diversity and a unique set of economic, political and domestic regulatory circumstances. The continued rise of imports has again led to concerns over the security of our crude oil resource but threats to thismore » system must be considered in light of the diversity and current setting of imported oil. This report develops several important issues concerning vulnerability to the disruption of oil imports: (1) The Middle East is not the major supplier of oil to the United States, (2) The US is not vulnerable to having its entire import stream disrupted, (3) Even in stable countries, there exist vulnerabilities to disruption of the export stream of oil, (4) Vulnerability reduction requires a focus on international solutions, and (5) DOE program and policy development must reflect the requirements of the diverse supply. Does this increasing proportion of imported oil create a {open_quotes}dependence{close_quotes}? Does this increasing proportion of imported oil present a vulnerability to {open_quotes}price shocks{close_quotes} and the tremendous dislocations experienced during the 1970`s? Finally, what is the vulnerability of supply disruptions from the current sources of imported oil? If oil is considered to be a finite, rapidly depleting resource, then the answers to these questions must be {open_quotes}yes.{close_quotes} However, if the supply of oil is expanding, and not limited, then dependence is relative to regional supply sources.« less

The Operations Targeting and Effects Synchronization Process in Northern Iraq

DTIC Science & Technology

2010-06-01

deployment. _____________ IMAGE: Coin of Marcus Aurelius . The secret of all victory lies in the organization of the non-obvious. — Marcus Aurelius , 121-180...CE IN THE EARLY 4th century BCE, more than five centuries before the great philosopher-emperor Marcus Aurelius made the observation quoted above

Early Warning System: a juridical notion to be built

NASA Astrophysics Data System (ADS)

Lucarelli, A.

2007-12-01

Early warning systems (EWS) are becoming effective tools for real time mitigation of the harmful effects arising from widely different hazards, which range from famine to financial crisis, malicious attacks, industrial accidents, natural catastrophes, etc. Early warning of natural catastrophic events allows to implement both alert systems and real time prevention actions for the safety of people and goods exposed to the risk However the effective implementation of early warning methods is hindered by the lack of a specific juridical frame. Under a juridical point of view, in fact, EWS and in general all the activities of prevention need a careful regulation, mainly with regards to responsibility and possible compensation for damage caused by the implemented actions. A preventive alarm, in fact, has an active influence on infrastructures in control of public services which in turn will suffer suspensions or interruptions because of the early warning actions. From here it is necessary to possess accurate normative references related to the typology of structures or infrastructures upon which the activity of readiness acts; the progressive order of suspension of public services; the duration of these suspensions; the corporate bodies or administrations that are competent to assume such decisions; the actors responsible for the consequences of false alarm, missed or delayed alarms; the mechanisms of compensation for damage; the insurance systems; etc In the European Union EWS are often quoted as preventive methods of mitigation of the risk. Nevertheless, a juridical notion of EWS of general use is not available. In fact, EW is a concept that finds application in many different circles, each of which require specific adaptations, and may concern subjects for which the European Union doesn't have exclusive competence as may be the responsibility of the member states to assign the necessary regulations. In so far as the juridical arrangement of the EWS, this must be

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoaf, C.R.; Guth, D.J.

The Air Risk Information Support Center (Air RISC) was initiated in early 1988 by the US Environmental Protection Agency`s (EPA) Office of Health and Environmental Assessment (OHEA) and the Office of Air Quality Planning and Standards (OAQPS) as a technology transfer effort that would focus on providing information to state and local environmental agencies and to EPA Regional Offices in the areas of health, risk, and exposure assessment for toxic air pollutants. Technical information is fostered and disseminated by Air RISCs three primary activities: (1) a {open_quotes}hotline{close_quotes}, (2) quick turn-around technical assistance projects, and (3) general technical guidance projects. 1more » ref., 2 figs.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miley, G.H.

Remarks made in the author{close_quote}s acceptance lecture for the 1995 Edward Teller Medal are presented and expanded. Topics covered include research on nuclear-pumped lasers, the first direct e-beam-pumped laser, direct energy conversion and advanced fuel fusion, plus recent work on inertial electrostatic confinement. {open_quote}{open_quote}Patience{close_quote}{close_quote} and {open_quote}{open_quote}optimism{close_quote}{close_quote} are viewed as essential elements needed by scientists following the {open_quote}{open_quote}zig-zag{close_quote}{close_quote} path to fusion energy production. {copyright} {ital 1996 American Institute of Physics.}

Piri Reis and the Columbus Map.

ERIC Educational Resources Information Center

Lunde, Paul

1993-01-01

Discusses the origins and impact of the Piri Reis map, an early world map based on the voyages of Columbus and 20 other source maps. Maintains that evidence exists that Christopher Columbus may have drawn part of the map. Includes lengthy quotes from the map's legend written by Reis. (CFR)

Comment on {open_quotes}Spontaneous Wave Pattern Formation in Vibrated Granular Materials{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bizon, C.; Shattuck, M.D.; Newman, J.T.

1997-12-01

A Comment on the Letter by Keiko M. Aoki and Tetsuo Akiyama, Phys.Rev.Lett.{bold 77}, 4166 (1996). The authors of the Letter offer a Reply. {copyright} {ital 1997} {ital The American Physical Society}

{open_quotes}Radon{close_quotes} - the system of Soviet designed regional waste management facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Horak, W.C.; Reisman, A.; Purvis, E.E. III

1997-07-01

The Soviet Union established a system of specialized regional facilities to dispose of radioactive waste generated by sources other than the nuclear fuel cycle. The system had 16 facilities in Russia, 5 in Ukraine, one in each of the other CIS states, and one in each of the Baltic Republics. These facilities are still being used. The major generators of radioactive waste they process these are research and industrial organizations, medical and agricultural institution and other activities not related to nuclear power. Waste handled by these facilities is mainly beta- and gamma-emitting nuclides with half lives of less than 30more » years. The long-lived and alpha-emitting isotopic content is insignificant. Most of the radwaste has low and medium radioactivity levels. The facilities also handle spent radiation sources, which are highly radioactive and contain 95-98 percent of the activity of all the radwaste buried at these facilities.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Norris, R.S.; Arkin, W.M.

The US. nuclear stockpile is at its lowest level since late 1958 or early 1959. In the past year, many weapons were returned to central military storage depots in the United States and funneled to the Energy Department's Pantex facility for final disassembly and disposal. This article presents a table showing the author's current estimate of the composition of the current operational stockpile, which contains some 10,500 warheads. Also categorized are warheads in [open quotes]inactive reserve[close quotes] and warheads awaiting eventual disassembly. The warheads are generally grouped as bombs, submarine-launched ballistic missiles, intercontinental ballistic missiles, air-launched cruise missiles, and sea-launchedmore » cruise missiles. Initial production dates and yield are listed for the warheads.« less

The Mercantile Business Coalition: A Narrative Analysis of a Learning Organization in an African American Community

ERIC Educational Resources Information Center

Harrell, Alma S.

2013-01-01

"A race that is solely dependent upon another for its economic existences sooner or later dies," this quote by Marcus Garvey highlighted the need for African American communities to think about the importance of economic development. This message was also heard by African Americans as early as the 1700s. Not only was the message about…

Chicano Literature of the Midwest: The Production of "Los Desarraigados."

ERIC Educational Resources Information Center

McAlpine, Dave

Following a brief discussion of the origins of the Chicanos in the Midwest, this paper surveys and quotes at length from several Spanish language periodicals produced in the Midwest between 1925 and the early 1980s. Discussion of the Chicano origins in the Midwest touches on emigration resulting from the Mexican Revolution of 1910-1917, the…

Strategic environmental management: The emergence of a new competitive requirement for American industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liddie, D.A.

1995-09-01

The environmental management infrastructure that has evolved in the United States over the last 25 years or so, since {open_quotes}the environment{close_quotes} burst into the national consciousness with events like Love Canal and Earth Day in the early 1970s. Increasingly, U.S. businesses must successfully compete with those of other nations to survive. Organizational re-engineering, cycle-time management, concurrent engineering, and lean manufacturing are just a few examples of corporate efforts to become better global competitors. U.S. environmental management systems, with their various inefficiencies, can hardly be excluded from these improvement initiatives. Businesses must find ways to reduce or control their environmental costsmore » and, where possible, find ways that {open_quotes}environment{close_quotes} can add positive value to their goods and services. Secondly, although considerable progress has been made in some areas, such as the development of cleaner combustion technology, the net total impact on our global ecosystem continues to rise. Ozone depletion, global warming, reduction in biodiversity, and depletion of non-renewable natural resources are a few of the more frequently cited examples. With the Earth`s population growing at a rate of approximately 100 million people per year, these global impacts can be expected to intensify. Social, regulatory, and economic forces will increasingly be brought to bear in addressing these growing impacts on our environment. As such, the environmental protection mandates placed on corporations can also be expected to increase over time.« less

The future of emissions trading in light of the acid rain experience

DOE Office of Scientific and Technical Information (OSTI.GOV)

McLean, B.J.; Rico, R.

1995-12-31

The idea of emissions trading was developed more than two decades ago by environmental economists eager to provide new ideas for how to improve the efficiency of environmental protection. However, early emissions trading efforts were built on the historical {open_quotes}command and control{close_quotes} infrastructure which has dominated U.S. environmental protection until today. The {open_quotes}command and control{close_quotes} model initially had advantages that were of a very pragmatic character: it assured large pollution reductions in a time when large, cheap reductions were available and necessary; and it did not require a sophisticated government infrastructure. Within the last five years, large-scale emission trading programsmore » have been successfully designed and started that are fundamentally different from the earlier efforts, creating a new paradigm for environmental control just when our understanding of environmental problems is changing as well. The purpose of this paper is to focus on the largest national-scale program--the Acid Rain Program--and from that experience, forecast when emission trading programs may be headed based on our understanding of the factors currently influencing environmental management. The first section of this paper will briefly review the history of emissions trading programs, followed by a summary of the features of the Acid Rain Program, highlighting those features that distinguish it from previous efforts. The last section addresses the opportunities for emissions trading (and its probable future directions).« less

‘A matter of faith, not science’: analysis of media coverage of prostate cancer screening in Australian news media 2003-2006

PubMed Central

MacKenzie, Ross; Chapman, Simon; Holding, Simon; McGeechan, Kevin

2007-01-01

Objective Despite a near universal absence of evidence-based policies supporting population screening for prostate cancer, the prostate-specific antigen (PSA) test is aggressively promoted in the media as a life-saving form of screening. The objective of this study was to examine media coverage of prostate-cancer screening in Australia. Design Frame analysis of all direct or attributed quotes about prostate cancer. Setting Australian capital city newspapers (February 2003-December 2006) and Sydney television news (January 2003-December 2006). Main outcome measures Quotes regarding prostate cancer screening: n=436 in newspapers and television news. Results Seven rhetorical frames were identified. 86% of all quotes framed prostate screening and its outcomes as desirable, associating PSA testing as being consonant with other early-detection cancer-control messages. Adverse surgical sequelae to screening were often minimized, scientific progress highlighted and gender equity appeals appropriated. Those questioning screening were vilified, with epidemiology being framed as an inferior form of knowledge than clinical experience. Conclusions Australian men are exposed to unbalanced and often non-evidence-based appeals to seek PSA testing. There is a disturbing lack of effort to redress this imbalance. PMID:18048709

The information retrieval system of {open_quotes}heat abd nass transfer{close_quotes} software complexes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsitsin, A.G.

A project is discussed which is aimed at creating the International Center for certification of software complexes (SC), intended to for soling various heat and mass transfer problems. Information on the experience gained in the operation of an information retrieval SC system is presented.

Some questions concerning safety on emergency landing in dense layers of the atmosphere of radionuclide energy sources based on plutonium-238 for autonomous station {open_quote}{open_quote}MARS-94/96{close_quote}{close_quote}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Makhorin, O.I.; Pustovalov, A.A.; Zhabin, V.N.

1996-03-01

This paper describes results of investigations of questions concerning integrity keeping for an ampula containing radionuclide fuel (Pu-238) under conditions of emergency landing in dense layers of the atmosphere and under conditions of fire on launching pad. {copyright} {ital 1996 American Institute of Physics.}

China Naval Modernization: Implications for U.S. Navy Capabilities - Background and Issues for Congress

DTIC Science & Technology

2014-02-28

established method for countering an opponent’s military capability. A September 30, 2011, press report, for example, quotes Lieutenant General Herbert ...to address it. We are unable to provide additional details.”... 122 Spencer Ackerman, “How To Kill...China Naval Modernization: Implications for U.S. Navy Capabilities Congressional Research Service 105 As early as Feb. 17 [2011], Lt. Gen. Herbert

On the entry of an emerging arbovirus into host cells: Mayaro virus takes the highway to the cytoplasm through fusion with early endosomes and caveolae-derived vesicles

PubMed Central

Carvalho, Carlos A.M.; Silva, Jerson L.; Oliveira, Andréa C.

2017-01-01

Mayaro virus (MAYV) is an emergent sylvatic alphavirus in South America, related to sporadic outbreaks of a chikungunya-like human febrile illness accompanied by severe arthralgia. Despite its high potential for urban emergence, MAYV is still an obscure virus with scarce information about its infection cycle, including the corresponding early events. Even for prototypical alphaviruses, the cell entry mechanism still has some rough edges to trim: although clathrin-mediated endocytosis is quoted as the putative route, alternative paths as distinct as direct virus genome injection through the cell plasma membrane seems to be possible. Our aim was to clarify crucial details on the entry route exploited by MAYV to gain access into the host cell. Tracking the virus since its first contact with the surface of Vero cells by fluorescence microscopy, we show that its entry occurs by a fast endocytic process and relies on fusion with acidic endosomal compartments. Moreover, blocking clathrin-mediated endocytosis or depleting cholesterol from the cell membrane leads to a strong inhibition of viral infection, as assessed by plaque assays. Following this clue, we found that early endosomes and caveolae-derived vesicles are both implicated as target membranes for MAYV fusion. Our findings unravel the very first events that culminate in a productive infection by MAYV and shed light on potential targets for a rational antiviral therapy, besides providing a better comprehension of the entry routes exploited by alphaviruses to get into the cell. PMID:28462045

76 FR 49816 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-11

... Quote Traders and Remote Streaming Quote Traders Entering Certain Option Day Limit Orders August 5, 2011... allow entry of day limit orders for the proprietary accounts of Streaming Quote Traders and Remote... proprietary accounts of Streaming Quote Traders (SQTs'') and Remote Streaming Quote Traders (``RSQTs''). The...

Engineering change in global climate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schneider, S.H.

1996-12-31

{open_quotes}With increased public focus on global warming and in the wake of the intense heat waves, drought, fires, and super-hurricanes that occurred in 1988 and 1989, interest in geoengineering has surged,{close_quotes} says Stephen H. Schneider, professor of biological science at Stanford University in Stanford, California. One scheme set forth in a National Research Council report proposes using 16-inch naval guns to fire aerosol shells into the stratosphere in hopes of offsetting {open_quotes}the radiative effects of increasing carbon dioxide,{close_quotes} Schneider says. Schneider, however, would prefer that we {open_quotes}seek measures that can cure our global {open_quote}addiction{close_quote} to polluting practices.{close_quotes} Rather than playingmore » God, he says we should {open_quotes}stick to being human and pursue problem - solving methods currently within our grasp.{close_quotes} Such strategies include efforts to promote energy efficiency and reduce our reliance on automobiles.« less

77 FR 67037 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-08

... the CBOE Stock Exchange, LLC (``CBSX'') to delete references to the automatic quote regeneration and....24(b) (Automatic Quote Regeneration) and Rule 53.24(c) (Quote Risk Monitor Function) from CBOE Stock... the automatic quote regeneration nor the quote risk monitor function has been made available or been...

City of Portland: Businesses for an environmentally sustainable tomorrow

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-12-01

The sustainable business development program in Portland (OR) is known as BEST. BEST stands for Businesses for an Environmentally Sustainable Tomorrow. The Portland Energy Office operates BEST as a {open_quotes}one-stop service center{close_quotes} for business owners and managers. BEST provides information and assistance on resource efficient buildings and business practices. The results of BEST`s two years of operation have been generally impressive. Nearly 150 new or expanding businesses have been connected with utility design assistance programs. Businesses have also received assistance with water conservation, telecommuting, construction debris recycling, and alternative fuel vehicles. BEST has received local and national publicity and BESTmore » services have been the topic at more than a dozen conferences, meetings, or other speaking engagements. A guidebook for communities wishing to start a similar program will be available in early 1996.« less

Preservice Teachers Listen to Families of Students with Disabilities and Learn a Disability Studies Stance

ERIC Educational Resources Information Center

Sauer, Janet S.; Kasa, Christi

2012-01-01

"These families must be so sad. I just wonder what they do and if they have any type of normal life." "I am not sure how I will work with parents. I think they probably look to the school for a lot of help." These quotes were taken from preservice teachers' papers early in their teacher education program, in which they were asked to describe what…

Molecular genetics of the glaucomas: Mapping of the first five {open_quotes}GLC{close_quotes} loci

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raymond, V.

1997-02-01

Glaucoma encompasses a complex of ocular-disease entities characterized by an optic neuropathy in which degeneration of retinal ganglion cells leads to a characteristic excavation of the head of the optic nerve. Such damage causes progressive narrowing of the visual fields and, when uncontrolled, blindness. Affected people often have ocular hypertension defined as intraocular pressures consistently >21 mm Hg in both eyes. Although ocular hypertension is no longer an obligatory diagnostic criterion for glaucoma, it is still recognized as one of the most important risk factors. A diagnosis of glaucoma is made after observation of the characteristic atrophy of the opticmore » nerve, which is associated with typical visual field defects. In 1992, the World Health Organization estimated that, in the global population, 5.2 million people were blind as a result of glaucoma, making it the third leading cause of blindness worldwide. The most common form is adult-onset primary open-angle glaucoma, which represents {ge}50% of all cases of glaucoma. Among Caucasians, this form of the disorder affects {approximately}2% of the population >45 years old. In African Americans, prevalence of adult-onset open-angle glaucoma is three to four times higher than that observed in White Americans. More than 15 million North Americans may have some form of glaucoma, but at least half of them may not be aware of it. 43 refs., 1 tab.« less

Comment on {open_quotes}Correlation between Compact Radio Quasars and Ultrahigh Energy Cosmic Rays{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoffman, C.M.

1999-09-01

A Comment on the Letter by Glennys R. Farrar and Peter L. Biermann, Phys. Rev. Lett. {bold 81}, 3579 (1998). The authors of the Letter offer a Reply. {copyright} {ital 1999} {ital The American Physical Society}

Early College, Early Success: Early College High School Initiative Impact Study

ERIC Educational Resources Information Center

Berger, Andrea; Turk-Bicakci, Lori; Garet, Michael; Song, Mengli; Knudson, Joel; Haxton, Clarisse; Zeiser, Kristina; Hoshen, Gur; Ford, Jennifer; Stephan, Jennifer; Keating, Kaeli; Cassidy, Lauren

2013-01-01

In 2002, the Bill & Melinda Gates Foundation launched the Early College High School Initiative (ECHSI) with the primary goal of increasing the opportunity for underserved students to earn a postsecondary credential. To achieve this goal, Early Colleges provide underserved students with exposure to, and support in, college while they are in…

Early Diagnosis and Early Intervention in Cerebral Palsy

PubMed Central

Hadders-Algra, Mijna

2014-01-01

This paper reviews the opportunities and challenges for early diagnosis and early intervention in cerebral palsy (CP). CP describes a group of disorders of the development of movement and posture, causing activity limitation that is attributed to disturbances that occurred in the fetal or infant brain. Therefore, the paper starts with a summary of relevant information from developmental neuroscience. Most lesions underlying CP occur in the second half of gestation, when developmental activity in the brain reaches its summit. Variations in timing of the damage not only result in different lesions but also in different neuroplastic reactions and different associated neuropathologies. This turns CP into a heterogeneous entity. This may mean that the best early diagnostics and the best intervention methods may differ for various subgroups of children with CP. Next, the paper addresses possibilities for early diagnosis. It discusses the predictive value of neuromotor and neurological exams, neuroimaging techniques, and neurophysiological assessments. Prediction is best when complementary techniques are used in longitudinal series. Possibilities for early prediction of CP differ for infants admitted to neonatal intensive care and other infants. In the former group, best prediction is achieved with the combination of neuroimaging and the assessment of general movements, in the latter group, best prediction is based on carefully documented milestones and neurological assessment. The last part reviews early intervention in infants developing CP. Most knowledge on early intervention is based on studies in high-risk infants without CP. In these infants, early intervention programs promote cognitive development until preschool age; motor development profits less. The few studies on early intervention in infants developing CP suggest that programs that stimulate all aspects of infant development by means of family coaching are most promising. More research is urgently needed

Do disk drives dream of buffer cache hits?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holt, A.

1994-12-31

G.E. Moore, in his book Principia Ethica, examines the popular view of ethics that deals with {open_quotes}what we ought to do{close_quotes} as well as using ethics to cover the general inquiry: {open_quotes}what is good?{close_quotes} This paper utilises Moore`s view of Ethics to examine computer systems performance. Moore asserts that {open_quotes}good{close_quotes} in itself is indefinable. It is argued in this report that, although we describe computer systems as good (or bad) a computer system cannot be good in itself, rather a means to good! In terms of {open_quotes}what we ought to do{close_quotes} this paper looks at what actions (would) bring aboutmore » good computer system performance according to computer science and engineering literature. In particular we look at duties, responsibilities and {open_quotes}to do what is right{close_quotes} in terms of system administration, design and usage. We further argue that in order to first make ethical observations with respect computer system performance and then apply them, requires technical knowledge which is typically limited to industry specialists and experts.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Louda, J.W.; Baker, E.W.

The premier molecular index for assessing the thermal maturity(history) of a bitumen is the DPEP-to-ETIO ratio. A restatement of that data set has appeared and is the %-DPEP. This is also preferred by the present authors. These indices (D/E, %D) chronicle the relative presence, absence, and changes in that relationship for porphyrins with ({open_quotes}DPEP{close_quotes}, {open_quotes}CAP{close_quotes}) or without ({open_quotes}ETIO{close_quotes}) exocyclic cycloalkyl ring moieties. An alternative index, the Alkylation Index (Al) has received scant attention since its inception nearly 2 decades ago. This index increasingly weights the higher (>C32), more alkylated, species and ratios those to the pigments at C32 and lower.more » The present report is an integration of several of our past and more recent studies on sediments, shales and petroleum crudes. The application of cross-plotting %-DPEP versus Alkylation Index (%D x Al), in order to {open_quote}fine-tune{close_quote} thermal maturity assessments, for source rocks and oils is covered. Potential problems due to (1) the {open_quote}contamination{close_quote} of mature bitumen with immature biomarkers or (2) biodegradation are also discussed.« less

Early Childhood Systems: Transforming Early Learning

ERIC Educational Resources Information Center

Kagan, Sharon Lynn, Ed.; Kauertz, Kristie, Ed.

2012-01-01

In this seminal volume, leading authorities strategize about how to create early childhood systems that transcend politics and economics to serve the needs of all young children. The authors offer different interpretations of the nature of early childhood systems, discuss the elements necessary to support their development, and examine how…

Cricket’s Contribution to India’s National Solidification

DTIC Science & Technology

2009-03-01

Taiwanization.”34 Their essay discusses the intentional introduction of baseball by the Japanese rulers in the early 20th century. Their study...explored how an authoritarian Japanese rule actively used baseball “as a tool to socialize the Taiwanese into Japanese culture and weaken their armed...resistance.”35 Junwei and Gordon quote a Japanese official tasked with implementing this program: Teaching barbarians to play baseball is an

The national labs and their future

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crease, R.P.

National laboratories of the USA, born with the atomic age and raised to prominence by the need for scientific superiority during the long Cold War, are facing the most critical challenge: how best to support the nation's current need to improve its international competitiveness through superior technology The charge that the national laboratories are [open quotes]Cold War relics[close quotes] that have outlived their usefulness is based on a misunderstanding of their mission, says Robert P. Crease, historian for Brookhaven National laboratory. Three of the labs-Los Alamos, Sandia, and Lawrence Livermore- are weapons laboratories and their missions must change. Oak Ridge,more » Argonne, and Brookhaven laboratories are multipurpose: basic research facilities with a continuing role in the world of science The national laboratory system traces its origins to the Manhattan Project. Over the next half-century, America's national labs grew into part of the most effective scientific establishment in the world, a much-copied model for management of large-scale scientific programs. In the early years, each lab defined a niche in the complex world of reactors, accelerators, and high-energy proton and electron physics. In the 1970s, several labs worked on basic energy sciences to help solve a national energy crisis. Today, the labs are pressured to do more applied research-research to transfer to the private sector and will have to respond by devising more effective ways of coordinating basic and applied research. But, Crease warns, [open quotes]It also will be essential that any commitment to applied research not take place at the cost of reducing the wellspring of basic research from which so much applied research flows. [open quotes]Making a solid and persuasive case for the independent value of basic research, and for their own role in that enterprise, may be the most important task facing the laboratories in their next half-century,[close quotes].« less

Early Intervention.

ERIC Educational Resources Information Center

Nathanson, Jeanne H., Ed.

1992-01-01

This theme issue focuses on early intervention. The four articles presented on this theme are: (1) "Deaf Infants, Hearing Mothers: A Research Report" (Kathryn P. Meadow-Orlans, and others), reporting findings on effects of auditory loss on early development; (2) "Maintaining Involvement of Inner City Families in Early Intervention Programs through…

Climbing the walls

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duey, R.

1997-07-01

{open_quotes}Integrated solutions{close_quotes} has become such a buzzword in the business world that it`s beginning to lose its semantic impact. But when the business is oil and gas and the integrated solutions revolve around information technology, the impact is very great indeed. A recent Cambridge Energy Research Associates study called the use of information technology within the petroleum industry a {open_quotes}quiet revolution.{close_quotes} The technology has been {open_quotes}a powerful, enabling factor in the survival and rebirth{close_quotes} of the industry since the price collapse of 1986, the report states, adding, {open_quotes}It will be even more important to the industry`s future, shaping business strategymore » and competitive advantage-- and company structure.{close_quotes} Like many other industries, oil and gas companies are moving away from hierarchical structures, relying on asset teams and other interdisciplinary approaches to maximize profits in an era of downsizing, volatile prices and stiff competition. {open_quotes}I think in the past the energy industry had a commodity mindset,{close_quotes} says Robert Shaw, senior vice president and head of the worldwide sector for Oracle Energy. {open_quotes}The industry was fairly controlled, stable and regulated, and there was a feeling that there wasn`t much to do except find oil, own reserves, refine as much as they can, run the pipe full, dispose of as much as they can and hopefully make a lot of money{close_quotes}.« less

The new politics of missile proliferation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karp, A.

1996-10-01

The author addresses the most consequential proliferation battle of the 1990s which occurred in Washington over the interpretation of the long-term threat to the United States from ballistic missiles. In the early 1970s, the stabilization of the US-Soviet strategic relationship led to new disputes over the other side`s future intentions, seen most graphically in Western debates over the implications of the Soviet SS-18 and SS-20 missile programs. Today, in much the same way, proliferation politics has matured to the point that surprises are few and the most challenging problem is anticipating the more distant future. Washington`s ballistic missile proliferation battlemore » was sparked by National Intelligence Estimate (NIE) 95-19, entitled {open_quotes}Emerging Threats to North America During the Next 15 Years,{close_quotes} released by the National Intelligence Council in November 1995. This document updated the evidence of regional missile programs reviewed in a similar report issued in 1993, and recapitulated the previous finding that {open_quotes}No country, other than the major declared nuclear powers, will develop or otherwise acquire a ballistic missile in the next 15 years that could threatened the contiguous 48 states or Canada.{close_quotes} The new report confirmed what several other studies of missile proliferation had already established: that besides the five nuclear-weapon states (the United States, Russia, China, France and Britain), only India, Israel and Japan are in a position to develop an ICBM during the foreseeable future, and while all have relevant capabilities, none are undertaking the steps necessary to develop an actual ICBM.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burwood, R.; Fortems, G.; Mycke, B.

Deposited under lacustrine conditions during the rift-phase opening of the southern Atlantic, the lower Congo Bucomazi Formation is a highly productive source rock sequence. Reaching considerable thickness (1.8 km), a heterogeneous organofacies reflects both rapid accumulation and changing conditions during Early Cretaceous Barremian sedimentation. As a component of organofacies, low resolution studies showed kerogen kinetic parameters (Ea/A) varied widely according to the gross paleoenvironmental conditions prevailing during deposition. As a a general trend, refractory (type I, higher Ea) kerogens of the [open quotes]basin fill[close quotes] Organic Rich Zone (ORZ) give way to more labile (type II, lower Ea) assemblages inmore » the up-section [open quotes]sheet drape[close quotes] sediments. At higher resolution, a considerable fine structure in Ea fluctuation, presumably reflecting micropaleoenvironment control, becomes evident. Using Ea values assembled for the Bucomazi type section, subsidence modeling for a Ponta Vermelha depocenter section showed a wide disparity in behavior. Being more representative of the sheet-drape episode, type II assemblages matured earlier, at lesser overburdens, and provided the initial hydrocarbon charge. For the ORZ assemblages, the dominant type I component was of retarded maturation, only becoming productive at commensurately greater overburdens. Cumulatively, these events merge to provide an extended period of hydrocarbon generation with implications for production of aggregate oils of varied emplacement histories. Significantly, the net effect of the observed Ea contrast results in the less prolific (but more labile) uppermost Bucomazi assuming a more important charging role than the ORZ of superior source richness. The latter can only realize its full potential under the greatest overburdens attainable in the most subsident depocenters.« less

Infusing Early Childhood Mental Health into Early Intervention Services

ERIC Educational Resources Information Center

Grabert, John C.

2009-01-01

This article describes the process of enhancing early childhood mental health awareness and skills in non-mental health staff. The author describes a pilot training model, conducted the U.S. Army's Early Intervention Services, that involved: (a) increasing early childhood mental health knowledge through reflective readings, (b) enhancing…

78 FR 27267 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-09

... Change To Amend Remote Streaming Quote Trader Fees and Reference a Remote Streaming Quote Trader... to Remote Streaming Quote Traders or RSQTs. The text of the proposed rule change is available on the... Remote Streaming Quote Traders Organizations (``RSQTOs'') with as many as three affiliated RSQTs.\\3...

77 FR 67040 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-08

... Proposal Regarding Quote Mitigation November 2, 2012. Pursuant to Section 19(b)(1) under the Securities... (Quote Mitigation) and refine the current quote mitigation strategy for its options trading facility, BOX Market LLC (``BOX'') by replacing the current quote mitigation rule with a ``holdback timer'' mechanism...

DOE standard 3009 - a reasoned, practical approach to integrating criticality safety into SARs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vessard, S.G.

1995-12-31

In the past there have been efforts by the U.S. Department of Energy (DOE) to provide guidance on those elements that should be included in a facility`s safety analysis report (SAR). In particular, there are two DOE Orders (5480.23, {open_quotes}Nuclear Safety Analysis Reports,{close_quotes} and 5480.24, {open_quotes}Nuclear Criticality Safety{close_quotes}), an interpretive guidance document (NE-70, Interpretive Guidance for DOE Order 5480.24, {open_quotes}Nuclear Criticality Safety{close_quotes}), and DOE Standard DOE-STD-3009-94 {open_quotes}Preparation Guide for U.S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports.{close_quotes} Of these, the most practical and useful (pertaining to the application of criticality safety) is DOE-STD-3009-94. This paper is a reviewmore » of Chapters 3, 4, and 6 of this standard and how they provide very clear, helpful, and reasoned criticality safety guidance.« less

And deregulation shall lead me to lie down in green pastures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weidinger, G.

1995-06-01

This presentation briefly reviews the history of the IPP industry, the current state of competition, and potential opportunities for IPPs in a deregulated environment. Since the beginning of the PURPA created IPP industry, we have experienced many market phases. These began with {open_quotes}beat avoided cost,{close_quotes} followed by {open_quotes}find a need and fill it,{close_quotes} followed by {open_quotes}the bid fest,{close_quotes} to today`s {open_quotes}anything goes.{close_quotes} During this time, market clearing prices have declined from over 80/KwHr to 2-40/KwHr. Today`s partially deregulated electric market includes fierce competition and several new players in the game. Where surplus capacity exists, IPPs must compete with subsidized power.more » Long-term contracts are no longer widely available. Access to markets is constrained by less than open transmission. Even with these challenges, opportunities remain for the IPP supplier. Opportunities for advanced coal-fired power systems will be explored.« less

Large data series: Modeling the usual to identify the unusual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Downing, D.J.; Fedorov, V.V.; Lawkins, W.F.

{open_quotes}Standard{close_quotes} approaches such as regression analysis, Fourier analysis, Box-Jenkins procedure, et al., which handle a data series as a whole, are not useful for very large data sets for at least two reasons. First, even with computer hardware available today, including parallel processors and storage devices, there are no effective means for manipulating and analyzing gigabyte, or larger, data files. Second, in general it can not be assumed that a very large data set is {open_quotes}stable{close_quotes} by the usual measures, like homogeneity, stationarity, and ergodicity, that standard analysis techniques require. Both reasons dictate the necessity to use {open_quotes}local{close_quotes} data analysismore » methods whereby the data is segmented and ordered, where order leads to a sense of {open_quotes}neighbor,{close_quotes} and then analyzed segment by segment. The idea of local data analysis is central to the study reported here.« less

Monitored plutonium aerosols at a soil cleanup site on Johnston Atoll

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shinn, J.H.; Fry, C.O.; Johnson, J.S.

1996-01-23

Suspended plutonium in air was monitored for four periods near the operation of a stationary sorting system used to {open_quotes}mine{close_quotes} contaminated soil on Johnston Atoll. The monitoring periods were 14 October-14 November 1992, 20 October-15 November 1993, 16 August-3 November 1994, and 17 February-27 February 1995. Pairs of high volume air samplers were located at each of four locations of the process stream: the {open_quotes}spoils pile{close_quotes} that was the feedstock, the {open_quotes}plant area{close_quotes} near the hot soil gate of the sorter, the {open_quotes}clean pile{close_quotes} conveyer area where sorted clean soil was moved, and the {open_quotes}oversize soil{close_quotes} crushing area. These locationsmore » were monitored only during the working hours, while air monitoring was also done at an upwind, {open_quotes}background{close_quotes} area 24-hours per day. The median concentrations of Pu in {open_quotes}workplace{close_quotes} air (combined spoils pile, plant area, and clean pile sites) in 1992 was 397 aCi/m{sup 3} (15 {mu}Bq/m{sup 3}), but increased to median values of 23000 aCi/m{sup 3} (852 {mu}Bq/m{sup 3}) in August-November 1994 and 29800 aCi/m{sup 3} (1100 {mu}Bq/m{sup 3}) in February 1995. The highest median value at the worksites (29800 aCi/m{sup 3}) was more than 200 times lower than the regulatory level. The highest observed value was 84200 aCi/m{sup 3} at the spoils pile site, and this was more than 70 times lower than the regulatory level. The conclusion was that, in spite of the dusty environment, and the increased level of specific activity, we did not find that the soil processing posed any significant risk to workers during the observation periods 1992-1995.« less

Early Literacy and Early Numeracy: The Value of Including Early Literacy Skills in the Prediction of Numeracy Development

ERIC Educational Resources Information Center

Purpura, David J.; Hume, Laura E.; Sims, Darcey M.; Lonigan, Cristopher J.

2011-01-01

The purpose of this study was to examine whether early literacy skills uniquely predict early numeracy skills development. During the first year of the study, 69 3- to 5-year-old preschoolers were assessed on the Preschool Early Numeracy Skills (PENS) test and the Test of Preschool Early Literacy Skills (TOPEL). Participants were assessed again a…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaba, J.M.

Three areas are addressed in this paper: generic issues that arise simply in the process of decision-making under environmental statutes; different decision-making standards under various environmental statutes; and efforts to legislate a {open_quotes}safe{close_quotes} or {open_quotes}acceptable{close_quotes} risk from exposure to carcinogenic chemicals.

78 FR 49586 - Self-Regulatory Organizations; Miami International Securities Exchange LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-14

... Market Maker Standard quote server as a gateway for communicating eQuotes to MIAX. Because of the... connect the Limited Service Ports to independent servers that host their eQuote and purge functionality... same server for all of their Market Maker quoting activity. Currently, Market Makers in the MIAX System...

77 FR 4068 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-26

... Fees; (2) B. Streaming Quote Trader (``SQT'') Fees; and (3) C. Remote Streaming Quote Trader (``RSQT...\\ Streaming Quote Trader (``SQT'') Fees, Remote Streaming Quote Trader (``RSQT'') Fees, Options Trading Floor... accordance with the provisions of 5 U.S.C. 552, will be available for Web site viewing and printing in the...

Advanced development of non-discoloring EVA-based PV encapsulants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holley, W.H.; Galica, J.P.; Argo, S.C.

1996-01-01

The purpose of this investigation was to better define the problem of field yellowing of EVA-based PV encapsulant, through laboratory study of probable chemical mechanisms and the development of stabilization strategies for protecting EVA from discoloration. EVA from fielded modules was analyzed for vinyl acetate content, unsaturation, and additive levels. These test results were then compared to results from Xenon Arc Weather-Ometer aged glass/EVA/glass laminates made in the laboratory. Variables evaluated in Weather-Ometer aged laminates included ``standard-cure`` A9918P EVA, ``fast-cure`` 15295P EVA, low iron glass superstrate containing cerium oxide, and systematic elimination or addition of specific additives. Six significant findingsmore » were revealed: 1) Improved ``standard-cure`` and ``fast-cure`` type EVA encapsulants, formulations X9903P and X15303P, respectively, showed little or no yellowing after extended Weather-Ometer exposure; 2) The use of {open_quote}{open_quote}fast-cure{close_quote}{close_quote} EVA reduced discoloration when compared with {open_quote}{open_quote}standard-cure{close_quote}{close_quote} A9918P EVA; 3) Glass superstrate containing cerium oxide resulted in a reduced rate of EVA discoloration; 4) {open_quote}{open_quote}Fast-cure{close_quote}{close_quote} EVA used with glass superstrate containing cerium oxide showed no visible yellowing after 32 weeks in the Weather-Ometer{emdash}a period estimated to be roughly equivalent to 20{endash}30 years of exposure in the Southwest; 5) Severely discolored EVA samples from the field showed no measurable loss of acetate group and little detectable unsaturation; and 6) EVA encapsulant with a Tefzel cover exhibited no yellowing after extended Weather-Ometer exposure. {copyright} {ital 1996 American Institute of Physics.}« less

Brachytherapy in early prostate cancer--early experience.

PubMed

Jose, B O; Bailen, J L; Albrink, F H; Steinbock, G S; Cornett, M S; Benson, D C; Schmied, W K; Medley, R N; Spanos, W J; Paris, K J; Koerner, P D; Gatenby, R A; Wilson, D L; Meyer, R

1999-01-01

Use of brachytherapy with radioactive seeds in the management of early prostate cancer is commonly used in the United States. The early experience has been reported from the prostate treatment centers in Seattle for the last 10 years. In this manuscript we are reporting our early experience of 150 radioactive seed implantations in early stage prostate cancer using either Iodine 125 or Palladium 103 seeds. The average age of the patient is 66 years and the median Gleason score is 5.4 with a median PSA of 6. A brief description of the evolution of the treatment of prostate cancer as well as the preparation for the seed implantation using the volume study with ultrasound of the prostate, pubic arch study using CT scan of the pelvis and the complete planning using the treatment planning computers are discussed. We also have described the current technique which is used in our experience based on the Seattle guidelines. We plan a follow-up report with the results of the studies with longer follow-up.

Safeguards and retrievability from waste forms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Danker, W.

1996-05-01

This report describes issues discussed at a session from the PLutonium Stabilization and Immobilization Workshop related to safeguards and retrievability from waste forms. Throughout the discussion, the group probed the goals of disposition efforts, particularly an understanding of the {open_quotes}spent fuel standard{close_quotes}, since the disposition material form derives from these goals. The group felt strongly that not only the disposition goals but safeguards to meet these goals could affect the material form. Accordingly, the Department was encouraged to explore and apply safeguards as early in the implementation process as possible. It was emphasized that this was particularly true for anymore » planned use of existing facilities. It is much easier to build safeguards approaches into the development of new facilities, than to backfit existing facilities. Accordingly, special safeguards challenges are likely to be encountered, given the cost and schedule advantages offered by use of existing facilities.« less

Duchenne muscular dystrophy and idiopathic hyperCKemia segregating in a family

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frydman, M.; Straussberg, R.; Shomrat, R.

1995-09-11

A 7-month-old boy with gross motor delay and failure to thrive presented with rhabdomyolysis following an acute asthmatic episode. During hospitalization an electrocardiographic conversion to a Wolff-Parkinson-White type 1 (WPW) pattern took place. Duchenne muscular dystrophy (DMD) was suspected based on elevated creatine kinase (CK) serum levels, muscle biopsy, and family history. The diagnosis was confirmed by molecular analysis, which documented a deletion corresponding to cDNA probe 1-2a in the dystrophin gene, in the propositus and in an affected male cousin of his mother. {open_quotes}Idiopathic{close_quotes} hyperCKemia was found in the propositus, his father, and 5 of his relatives. We suggestmore » that the unusually early and severe manifestations of DMD in this patient may be related to the coincidental inheritance of the maternal DMD gene and of a paternal gene, causing hyperCKemia. 13 refs., 3 figs., 1 tab.« less

Total recall. [Refinancing of debt by utilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hemptstead, J.

1994-02-15

The dramatic rally in the US treasury markets in 1992 and 1993 offered utility treasurers a unique opportunity to radically restructure their outstanding debt profiles by redeeming and refunding callable and refundable bonds. Since January 1991, utility companies have issued over $100 billion of nonconvertible debt securities; 53 percent of these companies indicated [open quotes]refinancing fixed income securities[close quotes] as the primary use of proceeds. After approximately 18 months of heavy refunding activity, utility treasurers have nearly exhausted the supply of currently callable debt and are now looking at alternative methods of reducing their embedded cost of debt and increasingmore » cash flows. The two most common methods are to repurchase highest-cost noncallable and/or currently nonrefundable bonds through [open quotes]open-market repurchases[close quotes] and [open quotes]tender offers.[close quotes] A third, less popular and less used, method is the [open quotes]defeasance[close quotes]. This article describes the advantages, disadvantages, and economic effects of these three types of financing.« less

Pt/Al{sub 2}O{sub 3} catalysts and Pt-Sn/Al{sub 2}O{sub 3} catalysts prepared by two different methods: Hydrogen pressure effects in the reactions of n-hexane

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paal, Z.; Gyory, A.; Uszkurat, I.

Pt-Sn/Al{sub 2}O{sub 3} catalysts were prepared using two different methods, namely, by {open_quotes}traditional{close_quotes} coimpregnation with H{sub 2}PtCl{sub 6} and SnCl{sub 4} and by a {open_quotes}new{close_quotes} method in which the bimetallic complex precursor [Pt(NH{sub 3}){sub 4}] [SnCl{sub 6}] is prepared on the support. Their catalytic activity and selectivity in n-hexane reactions were studied as a function of the hydrogen pressure (60-480 Torr) and compared with those of monometallic Pt/Al{sub 2}O{sub 3} catalysts using H{sub 2}PtCl{sub 6} or [Pt(NH{sub 3}){sub 4}]Cl{sub 2} as Pt precursors. Pt/Al{sub 2}O{sub 3} ex [Pt(NH{sub 3}){sub 4}]Cl{sub 2} showed very low dispersion and exhibited high selectivity inmore » reactions attributed to multiatomic ensembles. The results with bimetallic catalysts can be rationalized in terms of two phases being present, a PtSn alloy phase plus Pt in fine distribution. The {open_quotes}new{close_quotes} Pt-Sn/Al{sub 2}O{sub 3} from the bimetallic precursor contains the two metals in a better dispersion, resulting in a larger number of atomically dispersed surface Pt active sites. This catalyst gave more isomers (and methylcyclopentane) and fewer fragments and less benzene than the {open_quotes}traditional{close_quotes} sample. The {open_quotes}new{close_quotes} Pt-Sn/Al{sub 2}O{sub 3} sample possessed good long-term stability. The {open_quotes}traditional{close_quotes} sample lost some of its activity and its high hydrogenolysis selectivity during long use; i.e., it approached the catalytic properties of the {open_quotes}new{close_quotes} sample. Both samples are potential candidates as catalysts with high isomerizing and low aromatic selectivities (up to 75% isohexanes plus methylcyclopentane as opposed to a maximum of 20%, benzene). The results could be explained sufficiently with a geometric model, electronic interactions playing a less important role in the catalytic phenomena observed. 59 refs., 9 figs., 5

Early literacy and early numeracy: the value of including early literacy skills in the prediction of numeracy development.

PubMed

Purpura, David J; Hume, Laura E; Sims, Darcey M; Lonigan, Christopher J

2011-12-01

The purpose of this study was to examine whether early literacy skills uniquely predict early numeracy skills development. During the first year of the study, 69 3- to 5-year-old preschoolers were assessed on the Preschool Early Numeracy Skills (PENS) test and the Test of Preschool Early Literacy Skills (TOPEL). Participants were assessed again a year later on the PENS test and on the Applied Problems and Calculation subtests of the Woodcock-Johnson III Tests of Achievement. Three mixed effect regressions were conducted using Time 2 PENS, Applied Problems, and Calculation as the dependent variables. Print Knowledge and Vocabulary accounted for unique variance in the prediction of Time 2 numeracy scores. Phonological Awareness did not uniquely predict any of the mathematics domains. The findings of this study identify an important link between early literacy and early numeracy development. Copyright © 2011 Elsevier Inc. All rights reserved.

Early Childhood Special Education and Early Intervention Personnel Preparation Standards of the Division for Early Childhood: Field Validation

ERIC Educational Resources Information Center

Cochran, Deborah C.; Gallagher, Peggy A.; Stayton, Vicki D.; Dinnebeil, Laurie A.; Lifter, Karin; Chandler, Lynette K.; Christensen, Kimberly A.

2012-01-01

Results of the field validation survey of the revised initial and new advanced Council for Exceptional Children (CEC) Division for Early Childhood (DEC) early childhood special education (ECSE)/early intervention (EI) personnel standards are presented. Personnel standards are used as part of educational accountability systems and in teacher…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Metcalf, R.L.

The proliferation of xenobiotic chemicals in the global environment poses living problems for each of us aboard {open_quotes}spaceship earth.{close_quotes} Seven case studies are presented that illustrate the magnitude of the problem that can result from waiting to identify toxic hazards until there have been decades of {open_quotes}human guinea pig{close_quotes} exposure. 25 refs., 5 tabs.

Early Attachment Relationships and the Early Childhood Curriculum

ERIC Educational Resources Information Center

Cortazar, Alejandra; Herreros, Francisca

2010-01-01

This article explores the relationship between attachment theory and the early childhood curriculum. During the first years of life children develop early attachment relationships with their primary caregivers. These attachment relationships, either secure or insecure, will shape children's socio-emotional development. In the USA, the predominant…

Special Inspector General for Afghanistan Reconstruction Quarterly Report to the United States Congress

DTIC Science & Technology

2015-07-30

revenue and feels limited accountability pressure from citizens may do little to build institutions or develop the economy. Resource wind - falls or...reported as serving in the ANDSF increased, their percentage of the overall force slipped below 1%, to 0.99%, due to the greater gains in the overall...likely occur between late July and early August. Ghani was quoted refer- ring to the Taliban as “brothers” and said the “Taliban are Afghans, they are

Comparison of DOE and NIRMA approaches to configuration management programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, E.Y.; Kulzick, K.C.

One of the major management programs used for commercial, laboratory, and defense nuclear facilities is configuration management. The safe and efficient operation of a nuclear facility requires constant vigilance in maintaining the facility`s design basis with its as-built condition. Numerous events have occurred that can be attributed to (either directly or indirectly) the extent to which configuration management principles have been applied. The nuclear industry, as a whole, has been addressing this management philosophy with efforts taken on by its constituent professional organizations. The purpose of this paper is to compare and contrast the implementation plans for enhancing a configurationmore » management program as outlined in the U.S. Department of Energy`s (DOE`s) DOE-STD-1073-93, {open_quotes}Guide for Operational Configuration Management Program,{close_quotes} with the following guidelines developed by the Nuclear Information and Records Management Association (NIRMA): 1. PP02-1994, {open_quotes}Position Paper on Configuration Management{close_quotes} 2. PP03-1992, {open_quotes}Position Paper for Implementing a Configuration Management Enhancement Program for a Nuclear Facility{close_quotes} 3. PP04-1994 {open_quotes}Position Paper for Configuration Management Information Systems.{close_quotes}« less

A feasibility study to determine if there is a market for automatic meter-reading devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hilberg, G.R.

1996-08-01

For many utilities the cost of manually reading meters is increasing due to personnel expenses and equipment costs. The current system of manual meters provides little ability for the utility to reduce costs. To reduce meter reading costs the utility must automate the manual system and reduce personnel expenses. A water utility in San Diego county was studied to calculate the cost of reading individual water meters. This would allow for the selective replacement of {open_quotes}high-cost{close_quotes} meters to quickly reduce meter-reading costs while limiting the necessary capital investments. As the {open_quotes}high-cost{close_quotes} meters are selectively replaced, a utility with a significantmore » difference in individual meter reading costs could save three to five dollars per meter per year. This study showed that the {open_quotes}high-cost{close_quotes} meters were six times more expensive to read than the average meter. Additionally, AMR systems increase the information available to consumers and to the utility on usage patterns and problems. The challenge was to cost effectively identify the {open_quotes}high-cost{close_quotes} meters. The costs to collect these data were less than $500.« less

Rich, poor share stake in poverty, pollution link

DOE Office of Scientific and Technical Information (OSTI.GOV)

DeCanio, S.J.

A dirty environment and poverty go together, and this link between environmental protection and economic development is creating a new basis for international cooperation, says Stephen J. DeCanio of the University of California at Santa Barbara. [open quotes]Both developed and developing countries have a stake in solving the development/environment impasse,[close quotes] DeCanio adds. [open quotes]Furthermore, the link between these problems offers a fresh opportunity to make progress on both fronts.[close quotes] He says environmental protection expenditures by developed countries can be used to promote the sustainable economic growth of those countries struggling to escape from poverty. The money could bemore » collected in several ways, he notes: from various types of environmental taxes, such as a carbon tax; from environmental user fees; from [open quotes]debt-for nature[close quotes] swaps; and from tradable emissions permits. Such mechanisms transfer resources to developing countries, where they can be applied to economic development-a desired objective, according to DeCanio. [open quotes]The benefits of equitable worldwide growth and development outweigh any temporary loss of wealth developed countries may experience as a result of environmental transfers,[close quotes] he asserts.« less

Comments on {open_quotes}interpretations of quantum mechanics, joint measurement of incompatible observables, and counterfactual definiteness{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stapp, H.P.

1994-12-01

Some seeming logical deficiencies in a recent paper are described. The author responds to the arguments of the work by de Muynck, De Baere, and Martens (MDM), who argue it is widely accepted today that some sort of nonlocal effect is needed to resolve the problems raised by the works of Einstein, Podolsky, and Rosen (EPR) and John Bell. In MBM a variety of arguments are set forth that aim to invalidate the existing purported proofs of nonlocality and to provide, moreover, a local solution to the problems uncovered by EPR and Bell. Much of the argumentation in MBM ismore » based on the idea of introducing `nonideal` measurements, which, according to MBM, allow one to construct joint probability distributions for incompatible observables. The existence of a bona fide joint probability distribution for the incompatible observables occurring in the EPRB experiments would entail that Bell`s inequalities can be satisfied, and hence that the mathematical basis for the nonlocal effects would disappear. This relult would apparently allow one to eliminate the need for nonlocal effects by considering experiments of this new kind.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roos, E.; Maier, V.; Nagel, G.

The break preclusion concept is based on {open_quotes}KTA rules{close_quotes}, {open_quotes}RSK guidelines{close_quotes} and {open_quotes}Rahmenspeziflkation Basissicherheit{close_quotes}. These fundamental rules containing for example requirements on material, design, calculation, manufacturing and testing procedures are explained and the technical realisation is shown by means of examples. The proof of the quality of these piping systems can be executed by means of fracture mechanics calculations by showing that in every case the leakage monitoring system already detect cracks which are clearly smaller than the critical crack. Thus the leak before break behavior and the break preclusion concept is implicitly affirmed. In order to further diminish conservativitiesmore » in the fracture mechanics procedures, specific research projects are executed which are explained in this contribution.« less

Early Years Practitioners' Views on Early Personal, Social and Emotional Development

ERIC Educational Resources Information Center

Aubrey, Carol; Ward, Karen

2013-01-01

Current policy guidance stresses the need for early identification of obstacles to learning and appropriate intervention. New standards for learning (Early Years Foundation Stage) place personal, social and emotional development (PSED) as central to learning and development. This paper reports a survey and follow-up interviews with early years…

76 FR 49821 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-11

..., Streaming Quote Traders (``SQTs'') and Remote Streaming Quote Traders (``RSQTs'') to connect and send quotes... with the provisions of 5 U.S.C. 552, will be available for Web site viewing and printing in the...

Reformulated gasoline deal with Venezuela draws heat

DOE Office of Scientific and Technical Information (OSTI.GOV)

Begley, R.

A fight is brewing in Congress over a deal to let Venezuela off the hook in complying with the Clean Air Act reformulated gasoline rule. When Venezuela threatened to call for a GATT panel to challenge the rule as a trade barrier, the Clinton Administration negotiated to alter the rule, a deal that members of Congress are characterizing as {open_quotes}secret{close_quotes} and {open_quotes}back door.{close_quotes}

Negative ion production in large volume source with small deposition of cesium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacquot, C.; Pamela, J.; Riz, D.

1996-03-01

Experimental data on the enhancement of D{sup {minus}} (H{sup {minus}}) negative ion production due to cesium injection into a large volume multiampere negative ion source (MANTIS) are described. The directed deposition of small cesium amounts (5{endash}100 mg) from a compact, movable oven, placed into the central part of a MANTIS gas-discharge box was used. A calorimetrically measured D{sup {minus}} beam with an intensity up to 1.6 A and an extracted current density up to 4.2 mA/cm{sup 2} (beam energy 25 kV) was obtained. Exactly 30 mg of cesium provides at least one month of source operation (1000 pulses with amore » discharge pulse duration of 4 s). The effect of cesium on NI enhancement was immediately displayed after the distributed Cs deposition, but it needed some {open_quote}{open_quote}conditioning{close_quote}{close_quote} of cesium by tens of discharge pulses (or by several hours {open_quote}{open_quote}pause{close_quote}{close_quote}) in the case of a localized Cs deposition. No degradation of extraction-acceleration voltage holding on within the tested range of cesium injection was observed. {copyright} {ital 1996 American Institute of Physics.}« less

Molecular deletion mapping of the Y chromosome in males with idiopathic azoospermia reveals a new class of microdeletions located in middle Yq11

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farah, S.B.; Ramos, C.F.; Bortoletto, R.K.

1994-09-01

Microdeletions in proximal and distal Yq11 found {open_quotes}de novo{close_quotes} in males with idiopathic azoospermia or a severe oligospermia suggested that these Y mutations interrupt the gene structure(s) of a spermatogenesis function located in Yq11 and defined earlier as AZF. Using an extended interval map, dividing Yq11 into 22 subintervals (D1-D22) a third class of microdeletions could now be mapped in middle Yq11. It was found {open_quotes}de novo{close_quotes} in two sterile males with idiopathic azoospermia. Histological analysis of testes tissue sections of both males reveals arrest of spermatogenesis during the pachytene stage. Y-mutations in proximal Yq11 were usually associated to anmore » arrest of spermatogenesis before the proliferation phase of spermatogonia; the corresponding Y gene was defined as {open_quotes}AZFa{close_quotes}. It is, therefore, assumed that the new class of microdeletions, observed now in the middle of Yq11, disrupt another Y spermatogenesis gene expressed during the spermatocyte stage and defined earlier as {open_quotes}AZFb{close_quotes}. Experimental evidence presented during the meeting will try to confirm this view discussing a series of Y genes (AZFa,b,c,...) in Yq11 functioning at different stages during human spermatogenesis.« less

BASF confirms plans for world-scale cracker on the Gulf Coast

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wood, A.

BASF Corp. has confirmed plans that it will build a world-scale cracker on the Gulf Coast. The company has completed preliminary work, and {open_quotes}the results of our project analysis have been extremely encouraging,{close_quotes} says chemicals president Carl A. Jennings. {open_quotes}We`ll proceed with high priority to have the cracker ready for startup in second-half 2000.{close_quotes} The company says it will select a location for the project by mid-1977. In addition to considering its sites at Geismar, LA; Freeport, TX; and Altamira, Mexico, BASF says that {open_quotes}cooperative arrangements{close_quotes} are being looked at. That could include locating the project at a different site,more » adjacent to a feedstock source, according to Jennings. He says the project could also include joint venture partners.« less

Ethanol mandate thrown out by appeals court

DOE Office of Scientific and Technical Information (OSTI.GOV)

Begley, R.

1995-05-10

In a victory for the oil industry, a federal appeals court has overturned EPA`s mandate for ethanol use in reformulated gasoline (REG), saying the agency lacks authority to require 30% of the oxygenate market be reserved for ethanol. EPA says the ruling does not prevent ethanols use in RFG - {open_quotes}It only says that EPA cannot dictate the recipe.{close_quotes} Charles DiBona, president of the American Petroleum Institute (API), says {open_quotes}API and its member companies are not opposed to the use of ethanol as an oxygenate. We oppose this illegal mandate.{close_quotes} Urvan Sternfels, president of the National Petroleum Refiners Association, says,more » {open_quotes}Mandating market shares for any product is unsound economic policy.{close_quotes} The two trade groups led the legal battle against the ethanol requirement.« less

Early menarche, nulliparity and the risk for premature and early natural menopause.

PubMed

Mishra, Gita D; Pandeya, Nirmala; Dobson, Annette J; Chung, Hsin-Fang; Anderson, Debra; Kuh, Diana; Sandin, Sven; Giles, Graham G; Bruinsma, Fiona; Hayashi, Kunihiko; Lee, Jung Su; Mizunuma, Hideki; Cade, Janet E; Burley, Victoria; Greenwood, Darren C; Goodman, Alissa; Simonsen, Mette Kildevæld; Adami, Hans-Olov; Demakakos, Panayotes; Weiderpass, Elisabete

2017-03-01

Are parity and the timing of menarche associated with premature and early natural menopause? Early menarche (≤11 years) is a risk factor for both premature menopause (final menstrual period, FMP <40 years) and early menopause (FMP 40-44 years), a risk that is amplified for nulliparous women. Women with either premature or early menopause face an increased risk of chronic conditions in later life and of early death. Findings from some studies suggest that early menarche and nulliparity are associated with early menopause, however overall the evidence is mixed. Much of the evidence for a direct relationship is hampered by a lack of comparability across studies, failure to adjust for confounding factors and inadequate statistical power. This pooled study comprises 51 450 postmenopausal women from nine observational studies in the UK, Scandinavia, Australia and Japan that contribute to the International collaboration for a Life course Approach to reproductive health and Chronic disease Events (InterLACE). Age at menarche (categorized as ≤11, 12, 13, 14 and 15 or more years) and parity (categorized as no children, one child and two or more children) were exposures of interest. Age at FMP was confirmed by at least 12 months of cessation of menses where this was not the result of an intervention (such as surgical menopause due to bilateral oophorectomy or hysterectomy) and categorized as premature menopause (FMP before age 40), early menopause (FMP 40-44 years), 45-49 years, 50-51 years, 52-53 years and 54 or more years. We used multivariate multinomial logistic regression models to estimate relative risk ratio (RRR) and 95% CI for associations between menarche, parity and age at FMP adjusting for within-study correlation. The median age at FMP was 50 years (interquartile range 48-53 years), with 2% of the women experiencing premature menopause and 7.6% early menopause. Women with early menarche (≤11 years, compared with 12-13 years) were at higher risk of premature

Recent Coverage of Early Childhood Education Approaches in Open Access Early Childhood Journals

ERIC Educational Resources Information Center

Keskin, Burhanettin

2016-01-01

A content analysis of the coverage of the major approaches to early childhood education in the early childhood research journals, published between 2010 and 2014, that are early childhood research oriented and have free online access were investigated. Among 21 journals in early childhood education, two journals were selected for the content…

Early Educational Intervention, Early Cumulative Risk, and the Early Home Environment as Predictors of Young Adult Outcomes within a High-Risk Sample

ERIC Educational Resources Information Center

Pungello, Elizabeth P.; Kainz, Kirsten; Burchinal, Margaret; Wasik, Barbara H.; Sparling, Joseph J.; Ramey, Craig T.; Campbell, Frances A.

2010-01-01

The extent to which early educational intervention, early cumulative risk, and the early home environment were associated with young adult outcomes was investigated in a sample of 139 young adults (age 21) from high-risk families enrolled in randomized trials of early intervention. Positive effects of treatment were found for education attainment,…

The region of formation of the ultraviolet high temperature resonance lines in the eclipsing binary Beta Persei (Algol)

NASA Technical Reports Server (NTRS)

Brandi, E.; Garcia, L. G.; Kondo, Y.; Sahade, J.

1989-01-01

A new series of IUE observations of Beta Persei has shown that the high temperature resonance lines of Si IV and C IV arise in a region that surrounds the brighter, early-type component of the system. The continuum spectrum corresponds to that of a B8V object, and the value of E(B-V) that yielded the best match between the two IUE regions was 0.06, the value quoted for Beta Per in Jamar et al.'s (1976) Catalog.

Evolving Arms Transfer Rationales: The Case of Italy

DTIC Science & Technology

1987-06-01

began to 5 Libro Bianco-La Difesa, 1977, 57-92. 6 1bid. 23 reconstitute and reequip her armed forces. The 1950’s were tumultuous for the activity in...discussion of the early arms trade in Italy. 8 La Difesa-- Libro Bianco, Ministero della Difesa d’Italia, 1985. 74. 24 in recognizing the problem, the... Libro Bianco, p.xiv. This quote is a portion of the introduction to the White Book written by the Minister of Defense, Giovanni Spadolini. 31 however

[In-patient (early) rehabilitation].

PubMed

Wallesch, Claus-W; Lautenschläger, Sindy

2017-04-01

It is difficult to develop the financing and hospital provision of interventions for early rehabilitation within the diagnosis-related group (DRG) system. In addition to a range of partially rehabilitative complex interventions, the system recognizes three main forms of early rehabilitative interventions: geriatric, neurological/neurosurgical, and interdisciplinary and others. In this article, the appropriate definitions and cost-effectiveness of these procedures are analyzed and compared. The early rehabilitative interventions are characterized by constant cooperation in the therapeutic team, especially neurological early rehabilitation through the incorporation of nursing as a therapeutic profession. Whereas geriatric and neurological early rehabilitation are reflected in the DRG system, the former provided in many general hospitals and the latter mainly in specialized institutions, interdisciplinary early rehabilitation has only occasionally been represented in the DRG system so far. If all acute in-patients who require early rehabilitation should receive such an intervention, an additional fee must be implemented for this this interdisciplinary service.

African ancestry, early life exposures, and respiratory morbidity in early childhood.

PubMed

Kumar, R; Tsai, H-J; Hong, X; Gignoux, C; Pearson, C; Ortiz, K; Fu, M; Pongracic, J A; Burchard, E G; Bauchner, H; Wang, X

2012-02-01

Racial disparities persist in early childhood wheezing and cannot be completely explained by known risk factors. To evaluate the associations of genetic ancestry and self-identified race with early childhood recurrent wheezing, accounting for socio-economic status (SES) and early life exposures. We studied 1034 children in an urban, multi-racial, prospective birth cohort. Multivariate logistic regression was used to evaluate the association of genetic ancestry as opposed to self-identified race with recurrent wheezing (>3 episodes). Sequential models accounted for demographic, socio-economic factors and early life risk factors. Genetic ancestry, estimated using 150 ancestry informative markers, was expressed in deciles. Approximately 6.1% of subjects (mean age 3.1 years) experienced recurrent wheezing. After accounting for SES and demographic factors, African ancestry (OR: 1.16, 95% CI: 1.02-1.31) was significantly associated with recurrent wheezing. By self-reported race, hispanic subjects had a borderline decrease in risk of wheeze compared with African Americans (OR: 0.44, 95% CI: 0.19-1.00), whereas white subjects (OR: 0.46, 95% CI: 0.14-1.57) did not have. After further adjustment for known confounders and early life exposures, both African (OR: 1.19, 95% CI: 1.05-1.34) and European ancestry (OR: 0.84, 95% CI: 0.74-0.94) retained a significant association with recurrent wheezing, as compared with self-identified race (OR(whites) : 0.31, 95% CI: 0.09-1.14; OR(hispanic) : 0.47, 95% CI: 0.20-1.08). There were no significant interactions between ancestry and early life factors on recurrent wheezing. In contrast to self-identified race, African ancestry remained a significant, independent predictor of early childhood wheezing after accounting for early life and other known risk factors associated with lung function changes and asthma. Genetic ancestry may be a powerful way to evaluate wheezing disparities and a proxy for differentially distributed genetic and

African ancestry, early life exposures, and respiratory morbidity in early childhood

PubMed Central

Kumar, R.; Tsai, H.-J.; Hong, X.; Gignoux, C.; Pearson, C.; Ortiz, K.; Fu, M.; Pongracic, J. A.; Burchard, E. G.; Bauchner, H.; Wang, X.

2012-01-01

Summary Background Racial disparities persist in early childhood wheezing and cannot be completely explained by known risk factors. Objective To evaluate the associations of genetic ancestry and self-identified race with early childhood recurrent wheezing, accounting for socio-economic status (SES) and early life exposures. Methods We studied 1034 children in an urban, multi-racial, prospective birth cohort. Multivariate logistic regression was used to evaluate the association of genetic ancestry as opposed to self-identified race with recurrent wheezing (>3 episodes). Sequential models accounted for demographic, socio-economic factors and early life risk factors. Genetic ancestry, estimated using 150 ancestry informative markers, was expressed in deciles. Results Approximately 6.1% of subjects (mean age 3.1 years) experienced recurrent wheezing. After accounting for SES and demographic factors, African ancestry (OR: 1.16, 95% CI: 1.02–1.31) was significantly associated with recurrent wheezing. By self-reported race, hispanic subjects had a borderline decrease in risk of wheeze compared with African Americans (OR: 0.44, 95% CI: 0.19–1.00), whereas white subjects (OR: 0.46, 95% CI: 0.14–1.57) did not have. After further adjustment for known confounders and early life exposures, both African (OR: 1.19, 95% CI: 1.05–1.34) and European ancestry (OR: 0.84, 95% CI: 0.74–0.94) retained a significant association with recurrent wheezing, as compared with self-identified race (ORwhites: 0.31, 95% CI: 0.09–1.14; ORhispanic: 0.47, 95% CI: 0.20–1.08). There were no significant interactions between ancestry and early life factors on recurrent wheezing. Conclusions and Clinical Relevance In contrast to self-identified race, African ancestry remained a significant, independent predictor of early childhood wheezing after accounting for early life and other known risk factors associated with lung function changes and asthma. Genetic ancestry may be a powerful way to

76 FR 77038 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing and Immediate Effectiveness of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-09

... currently disincentivize aggressive displayed quoting by permitting pegging e-Quotes to eliminate the... to display aggressive prices, a participant may be reluctant to enter such displayed interest if a... interest. Accordingly, the proposal is designed to incentivize and reward aggressive displayed quoting by...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swallow, E.C.

This paper discusses developments in light collection which had their origin in efforts to construct high performance gas Cerenkov detectors for precision studies of hyperon beta decays at the ZGS. The resulting devices, know generally as {open_quotes}compound parabolic concentrators,{close_quotes} have found applications ranging from nuclear and particle physics experiments to solar energy concentration, instrument illumination, and understanding the optics of visual receptors. Interest in these devices and the ideas underlying them stimulated the development of a substantial new subfield of physics: nonimaging optics. This progression provides an excellent example of some ways in which unanticipated - and often unanticipatable -more » applied science and {open_quotes}practical{close_quotes} devices naturally emerge from first-rate basic science. The characteristics of this process suggest that the term {open_quotes}spinoff{close_quotes} commonly used to denote it is misleading and in need of replacement.« less

Refinery suppliers face tough times

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rotman, D.; Walsh, K.

1997-03-12

Despite a handful of bright spots in hydroprocessing and petrochemical sectors, economic woes plague much of the refinery and petrochemical catalysts business, as suppliers are feeling the impact of mature markets and refiners` ongoing cost cutting. Industry experts say the doldrums could spur further restructuring in the catalyst business, with suppliers scrambling for market share and jockeying for position in growing sectors. Expect further consolidation over the next several years, says Pierre Bonnifay, president of IFP Enterprises (New York). {open_quotes}There are still too many players for the mature [refinery catalyst] markets.{close_quotes} Others agree. {open_quotes}Only about seven [or] eight major suppliersmore » will survive,{close_quotes} says Robert Allsmiller, v.p./refinery and petrochemical catalysts at United Catalysts Inc. (UCI; Louisville, KY). {open_quotes}Who they [will be] is still up in the air.{close_quotes}« less

Art form as an object of cognitive modeling (towards development of Vygotsky`s semiotic model)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dmitriev, V.; Perlovsky, L.I.

1996-12-31

We suggest a further development of Vygotsky`s esthetic-semiotic model. First, we discuss Vygotsky`s model originally developed for the analysis of Ivan Bunin`s story {open_quotes}Light Breath{close_quotes}. Vygotsky analyzes formal methods used by Bunin to achieve a specific esthetic effect of {open_quote}lightness{close_quotes} while describing {open_quotes}dirty{close_quotes} events of everyday life. According to Vygotsky, this effect is achieved by ordering of events in a non-linear fashion. Vygotsky creams an airy pattern of smooth lines connecting events of story that he first orders linearly in time. And, he insists that this airy pattern creates an impression of airy lightness. In the language of semiotics, themore » esthetic effect is created by a specific structural organization of signs. Second, we present our critique of Vygotsky`s model. Although, we do not agree with Vygotsky`s sometimes moralistic judgements, and we consider the dynamics between inner personal values and received moral values to be more complicated than implied in his judgements, our critique in this paper is limited to the structure of his semiotic model. We emphasize that Vygotsky`s model does not explicitly account for a hierarchy of multiple levels of semiotic analysis. His analysis regularly slips from one level to another: (1) a lever of cognitive perception by a regular reader is confused with a level of creative genius of a writer; (2) {open_quotes}open{close_quotes} time of real world is mixed up with {open_quote}closed{close_quote} time of the story; (3) events are not organized by the hierarchy of their importance, nor in real world, nor in the inner model of the personages, nor in the story.« less

The air transportation industry birthplace of reliability-centered maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matteson, T.D.

1996-08-01

The 1980s and 1970s provided a timely opportunity for examining and radically changing the process called {open_quotes}preventive maintenance{close_quotes} as it is applied to the aircraft used for scheduled air transportation. The Federal Aviation Administration and four major airlines, United, American, Pan American and Trans World, were the {open_quotes}principals{close_quotes} in that process. While United`s work with the FAA on the Boeing 737 had opened the door a crack, the Boeing 747 presented a major opportunity to radically improve the process for maintenance program design. That program was guided by the results of United`s analyses of failure data from operations of severalmore » fleets, each larger than 100 aircraft, and the concurrent experience of American, Pan American and Trans World. That knowledge provided the insights necessary to support an entirely different approach to maintenance program design. As a result, while United`s existing maintenance program required scheduled overhaul of 339 items on each DC-8, it required overhaul of only 8 items on the B-7471 Although the initial thrust of that work focused on components of active systems, there was concurrent work focused on items whose principal function was to carry the loads associated with operations. That program focused on the classification of structurally-significant items and their classification as {open_quotes}safe life{close_quotes} or {open_quotes}damage tolerant{close_quote} to determine what periodic replacements or repeated inspections were required. That work came to the attention of the Department of Defense which supported preparation of the book-length report by F. Stanley Nowlan and Howard F. Heap at United Airlines entitled {open_quote}Reliability-Centered maintenance{close_quotes}.« less

A Study of the Relationship between Early Childhood Program Attributes and Early Childhood Reading Achievement

ERIC Educational Resources Information Center

Washington, Novella M.

2012-01-01

This quantitative correlational study focuses on the relationship between early childhood program attributes and early childhood reading success. Data will be gathered from early childhood sites with grades prekindergarten through second grade in which early childhood program attributes exist and early childhood reading is measured by the…

Early Childhood Diplomacy: Policy Planning for Early Childhood Development

ERIC Educational Resources Information Center

Vargas-Barón, Emily; Diehl, Kristel

2018-01-01

Children who are well nurtured, appropriately cared for, and provided with positive learning opportunities in their early years have a better chance of becoming healthy and productive citizens of nations and of the world. This article reviews the art and science of policy planning for early childhood development (ECD) from a diplomacy perspective.…

78 FR 4914 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving Proposed Rule Change To Amend...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-23

... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-68574; File No. SR-Phlx-2012-130] Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving Proposed Rule Change To Amend Performance Evaluations With Respect to Quote Submissions of Streaming Quote Traders and Remote Streaming Quote Traders...

Ag Data Commons Monthly Metrics | National Agricultural Library

Science.gov Websites

and Nutrition Service(84)","value":"Food and Nutrition Service(84)",&quot and Nutrition Service(84)","value":"Food and Nutrition Service(84)",&quot and Nutrition Service(84)","value":"Food and Nutrition Service(84)",&quot

Tertiary tectonic in the Tehuantepec Isthmus, Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lopez, F.A.

1993-02-01

A microplate model in the basement was proposed according to photointerpretation of satellite imagery and supported with microtectonic studies in the Tehuantepec's Isthmus. The microplate is located in the northwestern part of the [open quotes]Sierra de Chiapas,[close quotes] and structurally has lineaments that correspond with sinestral wrench faults oriented northeast-southwest and dextral faults oriented northwest-southeast. In the front of the microplate, these faults are joined in an arc form. The microplate began its movement forward to the north in the middle Tertiary. This movement originated in a regional compressional stress that was younger to the north. The stress changed themore » orientation of the anticline axis from northwest-southeast to west-east. In its western limit, the stress produces a sinestral shear stress that built a rotational deformation in the [open quotes]Sierra Atravesada,[close quotes] and represents a superimposed tectonic block over an ancient (laramide) orogeny. This system has also produced other secondary transtensional effects oriented northwest-southeast, represented along the [open quotes]Depression Central del Istmo.[close quotes] The microplate has formed a tensional system opening the [open quotes]Superior, Inferior, and Mar Muerto[close quotes] lagoons. The microplate is strongly related with the relief, seismic activity, and the tectonics of the salt of the Tehuantepec's Isthmus.« less

Informational temperature concept and the nature of self-organization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Shu-Kun

1996-12-31

Self-organization phenomena are spontaneous processes. Their behavior should be governed by the second law of thermodynamics. The dissipative structure theory of the Prigogine school of thermodynamics claims that {open_quotes}order out of chaos{close_quotes} through {open_quotes}self-organization{close_quotes} and challenges the validity of the second law of thermodynamics. Unfortunately this theory is questionable. Therefore we have to reconsider the related fundamental theoretical problems. Informational entropy (S) and information (I) are related by S = S{sub max} - I, where S{sub max} is the maximum informational entropy. This conforms with the broadly accepted definition that entropy is the information loss. As informational entropy concept hasmore » been proved to be useful, it will be convenient to define an informational temperature, T{sub I}. This can be related to energy E and the informational entropy S. Information registration is a process of {Delta}I > 0, or {Delta}S < 0, and involves the energetically excited states ({Delta}E > 0). Therefore, T{sub I} is negative, and has the opposite sign of the conventional thermodynamic temperature, T. This concept is useful for clarifying the concepts of {open_quotes}order{close_quotes} and {open_quotes}disorder{close_quotes} of static structures and characterizing many typical information loss processes of self-organization.« less

Overview of Play: Its Uses and Importance in Early Intervention/Early Childhood Special Education

ERIC Educational Resources Information Center

Lifter, Karin; Foster-Sanda, Suzanne; Arzamarski, Caley; Briesch, Jacquelyn; McClure, Ellen

2011-01-01

Play is a natural activity of early childhood, which has great relevance to the fields of early intervention, early childhood special education, and early childhood education. Within these fields, ongoing tensions persist in how play is described and used. These tensions compromise activities of assessment, intervention, and curriculum development…

Early Number Skills Gains and Mathematics Achievement: Intervening to Establish Successful Early Mathematics Trajectories

ERIC Educational Resources Information Center

Shanley, Lina; Clarke, Ben; Doabler, Christian T.; Kurtz-Nelson, Evangeline; Fien, Hank

2017-01-01

Early number skills, comprised of both informal and formal skills, are associated with later mathematics achievement. Thus, the development of foundational early number skills is an important aspect of early mathematics instruction. This study explored relations between early number skills gains and mathematics achievement for students at risk for…

Tank 241-C-112 vapor sampling and analysis tank characterization report. Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huckaby, J.L.

1995-05-31

Tank 241-C-112 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in {open_quotes}Program Plan for the Resolution of Tank Vapor Issues.{close_quotes} Tank 241-C-112 was vapor sampled in accordance with {open_quotes}Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.{close_quotes}

We Bomb, Therefore We Are: The Evolution of Terrorist Group Life Cycles

DTIC Science & Technology

1994-03-24

and arms robberies peaked during this phase, a marked qhift toward political action occurred. 𔃺°Quoted in Gilio , Tupamaros, 79 and 82. "•Ucbano...52. 蕀Quoted in Gilio , 120. 63 Claude Fly on 7 August 1970: and ended with abduction of British Ambassador Geoffrey Jackson on 8 January 1971...stabilize the present system "•’Quoted in della Porta, "Political Socialization," 273. 2 Quoted in Gilio , Tupamaros, 78. 2mIbid., 268. 14Ibid., 270. 124

Individual differences in early adolescents' latent trait cortisol (LTC): Relation to early adversity.

PubMed

Stroud, Catherine B; Chen, Frances R; Doane, Leah D; Granger, Douglas A

2016-09-01

Substantial evidence suggests that youth who experience early adversity exhibit alterations in hypothalamic pituitary adrenal (HPA) axis functioning, thereby increasing risk for negative health outcomes. However, few studies have explored whether early adversity alters enduring trait indicators of HPA axis activity. Using objective contextual stress interviews with adolescents and their mothers to assess early adversity, we examined the cumulative impact of nine types of early adversity on early adolescents girls' latent trait cortisol (LTC). Adolescents (n = 122; M age = 12.39 years) provided salivary cortisol samples three times a day (waking, 30 min post-waking, and bedtime) over 3 days. Latent state-trait modeling indicated that the waking and 30 min post-waking samples contributed to a LTC factor. Moreover, greater early adversity was associated with a lower LTC level. Implications of LTC for future research examining the impact of early adversity on HPA axis functioning are discussed. © 2016 Wiley Periodicals, Inc. Dev Psychobiol 58:700-713, 2016. © 2016 Wiley Periodicals, Inc.

Using Defined Processes as a Context for Resilience Measures

DTIC Science & Technology

2011-12-01

processes. 1 "W. Edwards Deming." BrainyQuote.com. Xplore Inc, 2010. Accessed September 22, 2011. http://www.brainyquote.com/quotes/quotes/w...process owner of this process element or another related organizational home page, e.g., Software Engineering Institute, IEEE or a government regulatory

Jet Fuel Hedging Strategies for the Department of Defense Through Use of Financial Derivatives

DTIC Science & Technology

2009-03-01

W. (n.d.). Warren Buffett Quotes. Retrieved November 2008, from Brainy Quote: http://www.brainyquote.com/quotes/authors/w/warren_buffett.html...Prices Tough to Swallow. Retrieved August 2008, from Washington Post: http://www.washingtonpost.com/wp- dyn/articles/A11303-2004Jun2.html Buffett

An overview of Pennsylvania`s experience with NORM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yusko, J.G.

1997-02-01

Although Pennsylvania may be thought of as the state who brought you indoor radon, courtesy of a discovery of a residence with radon concentrations in excess of a few thousand picocuries per liter, this is not the states only claim to NORM fame. In the early years of the twentieth century, Pennsylvania was the largest producer of radium, utilizing its industrial base to produce large quantities of this {open_quotes}miracle cure{close_quotes} from ores mined in the West, and transported to a separation and purification facility in Western Pennsylvania. The company successfully held off foreign and political pressure, and generated large quantitiesmore » of uranium tailings as well, until a fire one New Year`s Eve destroyed the separation plant, and the company faded from view. The tailings were remediated as part of the Uranium Mill Tailings, Remedial Action Project, on the only site east of the Mississippi River. This article goes on to discuss the states experiences with NORM in various projects, coming in contact with human populations from different sources.« less

Scurfy mice: A model for autoimmune disease

DOE Office of Scientific and Technical Information (OSTI.GOV)

Godfrey, V.L.

1993-01-01

Autoimmune disease-the condition in which the body attacks its own tissue-has been an object of public concern recently. Former President George Bush and his wife Barbara both are afflicted with Graves' disease in which the body's own immune system attakcs the thyroid gland. The safety of breast implants was called into question because of evidence that some recipients had developed autoimmune disorders such a rheumatoid arthritis, systemic lupus erythematosus, and scleroderma. Women, the media pointed out, have a higher-than-average incidence of many autoimmune disorders. These events suggest the need to know more about what makes the immune system work somore » well and what makes it go awry. At ORNL's Biology Division, progress is being in understanding the underlying causes of immune disease by studying mice having a disease that causes them to be underdeveloped; to have scaly skin, small ears, and large spleens; to open their eyes late; and to die early. These [open quotes]scurfy[close quotes]mice are helping us better understand the role of the thymus gland in autoimmune disease.« less

Reframing Early Childhood Leadership

ERIC Educational Resources Information Center

Stamopoulos, Elizabeth

2012-01-01

Rapid changes in Australian education have intensified the role of early childhood leaders and led to unprecedented challenges. The Australian Curriculum (ACARA, 2011), mandated Australian "National Quality Framework" (NQF) for Early Childhood Education & Care (DEEWR, 2010b) and the "National Early Years Learning Framework"…

Hydropower application of confined space regulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Franseen, H.W.

1995-12-31

OSHA`s {open_quotes}Permit Required Confined Space{close_quotes} rules, 1910.146, became effective April 15, 1993. Their rules define a {open_quotes}confined space{close_quotes} and {open_quotes}permit required confined space{close_quotes}; provide general requirements for those entering the confined space, for the attendant and entry supervisor; define what a confined space program and permit system should be; and describe training requirements and rescue considerations. Tapoco Inc., began preparing confined space procedures in 1992 using Alcoa Engineering Standards and OSHA`s proposed rules. A joint union management team was formed, and this team began evaluating spaces which meet the confined space definition. In 1993, employees were trained, and all entriesmore » into spaces were done according to Alcoa`s and OSHA`s proposed rules. Rescue teams have been trained at each site. Some unique confined spaces and or unique entry conditions have been encountered which have required extensive evaluation.« less

Report on annual utility oil buyers conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stambler, K.

1994-08-01

What was discussed at this year`s Utility Oil Buyers` Conference is summarized. This year`s conference was held in Boston and there were over 200 attendees representing over 130 different companies from the utility, oil trading, consulting and inspection industries. Attendees for this year`s came from as far away as Italy and Argentina. The mood at this year`s conference was somber, as each sector is feeling the effects of the decline in residual fuel oil demand--due to natural gas displacement, non-utility generation and an economy that is still lethargic. The topics that were covered ranged from {open_quotes}Life after Order 636{close_quotes} tomore » {open_quotes}Does Residual Fuel Oil Have a Future in a Utility Steam Boiler?{close_quotes} to {open_quotes}The Future of Shipping after OPA of 1990.{close_quotes} In addition, there were several topics that have been or will be covered at this conference.« less

Guaranteeing safety in spatially situated agents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kohout, R.C.; Hendler, J.A.; Musliner, D.J.

1996-12-31

{open_quote}Mission-critical{close_quotes} systems, which include such diverse applications as nuclear power plant controllers, {open_quotes}fly-by-wire{close_quotes} airplanes, medical care and monitoring systems, and autonomous mobile vehicles, are characterized by the fact that system failure is potentially catastrophic. The high cost of failure justifies the expenditure of considerable effort at design-time in order to guarantee the correctness of system behavior. This paper examines the problem of guaranteeing safety in a well studied class of robot motion problems known as the {open_quotes}asteroid avoidance problem.{close_quotes} We establish necessary and sufficient conditions for ensuring safety in the simple version of this problem which occurs most frequently inmore » the literature, as well as sufficient conditions for a more general and realistic case. In doing so, we establish functional relationships between the number, size and speed of obstacles, the robot`s maximum speed and the conditions which must be maintained in order to ensure safety.« less

When intelligence is in control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bellman, K.L.

Each time a discipline redefines itself, I look at it as a sign of growth, because often such redefinition means that there is new theory, new methods, or new {open_quotes}disciples{close_quote} from other disciplines who are stretching, enlarging, and deepening the field. Such is the case with semiotics. Deeply entwined with the concepts of {open_quotes}intelligent systems{close_quotes}, {open_quotes}intelligent control{close_quotes}, and complex systems theory, semiotics struggles to develop representations, notations (systems of representations), and models (functionally-oriented sets of related representations) to study systems that may or may not be usefully described as employing representations, notations, and models themselves. That last, of course, ismore » the main problem that semiotics faces. Semiotics, like psychology, philosophy, or any other self-referential discipline, is burdened by the eye attempting to study the eye or the mind studying the mind, or more to the point here, the modeler studying the modeling acts of others.« less

{open_quotes}The effects of diabetes on the activity of the enzyme glutamine: fructose-6-phosphate amindotransferase{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nelson, S.P.

1994-12-31

Hexsoamine synthetic pathway (HexNSP) controls the supply of essential substrates for glycoprotein synthesis. In vitro studies suggest that increased flux of glucose via the hexsoamine synthetic pathway may play a role in glucose induced insulin resistance of glucose transport. Glutamine: fructose-6-phosphate amindotransferase (GFAT) controls flux into the hexsoamine synthetic pathway; the major products are UDPN-acetylhexosamines (UDP.HexNac=UDP.GlcNAc= UDP.GalNac). I examined whether diabetes ({approximately} 7 days post intravenous streptozotocin, and genetically linked) affects the activity of glutamine: fructose-6-phosphate in rat and mouse skeletal muscle in vivo. Nucleotide linked HexNAc were analyzed by high pressure liquid chromatography(HPLC) in deproteinized hind limb muscle extracts.

Giant fields of the late 80s associated with type [open quotes]A[close quotes] subduction in South America

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duval, B.; Cramez, C.; Figuera, J.

1993-02-01

About 10 billion bbl of recoverable oil have been found in these three fields for which the petroleum generating subsystem is very similar. The potential source rocks are the organic sediments associated with the major downlap surface of the post-Pangea continental encroachment sedimentary cycle, i.e., MFS 91, 5 Ma (La Luna formation). However, the concentrating physico-chemical petroleum subsystem is quite different. The El Furrial/Musipan field is associated with a Tertiary foredeep basin overlying a generating Atlantic type passive margin. On the other hand, Cusiana and Ceuta fields are associated with a Tertiary foredeep basin developed over a generating back-arc basin.more » The different stacking of sedimentary basins controls the migration/entrapment petroleum subsystem. In El Furrial/Musipan, decollement surfaces and their associated thrusts are predominant whereas, in Ceuta and Cusiana the majority of compressional structures are created by tectonic inversions. These tectonic settings create different petroleum systems: (a) supercharged with low impedance and lateral drainage in El Furrial/Musipan, (b) normally charged with high impedance and vertically drained in Ceuta and Cusiana area. Each case requires appropriated exploration approaches.« less

Conference on the topic: {open_quotes}Exploration and production of petroleum and gas from chalk reservoirs worldwide{close_quotes}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuznetsov, V.G.

1995-07-01

More than 170 delegates from 14 countries in Europe, North America, Africa, and Asia took part in a conference on the topic: Exploration and Production of Petroleum and Gas from Chalk Reservoirs Worldwide. The conference was held in Copenhagen, Denmark in September,1994, and was a joint meeting of the American Association of Petroleum Geologists (AAPG), and the European Association of Petroleum Geoscientists and Engineers (EAPG). In addition to the opening remarks, 25 oral and nine poster reports were presented. The topics included chalk deposits as reservoir rocks, the occurrence of chalk deposits worldwide, the North Sea oil and gas fields,more » and other related topics.« less

Earth's early biosphere

NASA Technical Reports Server (NTRS)

Des Marais, D. J.

1998-01-01

Understanding our own early biosphere is essential to our search for life elsewhere, because life arose on Earth very early and rocky planets shared similar early histories. The biosphere arose before 3.8 Ga ago, was exclusively unicellular and was dominated by hyperthermophiles that utilized chemical sources of energy and employed a range of metabolic pathways for CO2 assimilation. Photosynthesis also arose very early. Oxygenic photosynthesis arose later but still prior to 2.7 Ga. The transition toward the modern global environment was paced by a decline in volcanic and hydrothermal activity. These developments allowed atmospheric O2 levels to increase. The O2 increase created new niches for aerobic life, most notably the more advanced Eukarya that eventually spawned the megascopic fauna and flora of our modern biosphere.

Value-Added Early Learning

ERIC Educational Resources Information Center

Dichter, Harriet

2011-01-01

Elected state leaders often prioritize economic prosperity and competitiveness, which provides an important opportunity too rarely taken for investing in early education. In 2003, Pennsylvania recognized the connection between early education and the economy, and smartly embraced early learning as part of its economic prosperity and…

Abnormal early cleavage events predict early embryo demise: sperm oxidative stress and early abnormal cleavage.

PubMed

Burruel, Victoria; Klooster, Katie; Barker, Christopher M; Pera, Renee Reijo; Meyers, Stuart

2014-10-13

Human embryos resulting from abnormal early cleavage can result in aneuploidy and failure to develop normally to the blastocyst stage. The nature of paternal influence on early embryo development has not been directly demonstrated although many studies have suggested effects from spermatozoal chromatin packaging, DNA damage, centriolar and mitotic spindle integrity, and plasma membrane integrity. The goal of this study was to determine whether early developmental events were affected by oxidative damage to the fertilizing sperm. Survival analysis was used to compare patterns of blastocyst formation based on P2 duration. Kaplan-Meier survival curves demonstrate that relatively few embryos with short (<1 hr) P2 times reached blastocysts, and the two curves diverged beginning on day 4, with nearly all of the embryos with longer P2 times reaching blastocysts by day 6 (p < .01). We determined that duration of the 2nd to 3rd mitoses were sensitive periods in the presence of spermatozoal oxidative stress. Embryos that displayed either too long or too short cytokineses demonstrated an increased failure to reach blastocyst stage and therefore survive for further development. Although paternal-derived gene expression occurs later in development, this study suggests a specific role in early mitosis that is highly influenced by paternal factors.

78 FR 22011 - Self-Regulatory Organizations; NYSE MKT LLC; Order Approving, on an Accelerated Basis, Proposed...

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2013-04-12

... Treat Orders, Market-Making Quoting Obligations, and Errors in Response to the Regulation NMS Plan To..., market-making quoting obligations, and errors in response to the Regulation NMS Plan to Address... Specialist has met its market-making quoting requirement pursuant to Rule 925.1NY(b) or a Market Maker has...

Deregulation 1993: Be careful what you wish for, you might get it

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scotto, D.

This article tries to assess the response at the electric industry to deregulation. The industry most probably will consolidate to reduce operating costs and expand access to other transmission grids. In addition, the cheapest power likely will be [open quotes]dedicated[close quotes] to retail customers (namely, those under a franchise obligation), and [open quotes]residual[close quotes] generating capacity will be placed in the wholesale market. Surplus capacity (the most expensive capacity) could be dedicated to the wholesale sector, allowing market forces to decide the future price of incremental generation. The outcome will be influenced heavily by corporate restructuring initiatives, regulatory willingness ormore » opposition, legal victories by large-scale users, and transmission access policies at the state and federal levels. Changes is definitely underway, but [open quotes]what[close quotes] the industry will look like is unclear. The financial consequences of this change are more easily identified. Evidently, internal pricing pressures and the breakdown of regulatory pricing structures (a trend that has been underway for nearly a decade) have combined to produce a more risky industry. To compensate investors, capital markets could demand increases returns and different corporate structures. Many of the financial benefits currently enjoyed by utilities, such as lower earnings/coverage tests and greater debt leverage than other [open quotes]industrial[close quotes] corporations, may have to change. Stepping out from under the protection of the regulatory umbrella will carry certain costs.« less

Health physics aspects of advanced reactor licensing reviews

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hinson, C.S.

1995-03-01

The last Construction Permit to be issued by the U.S. Nuclear Regulatory Commission (NRC) for a U.S. light water reactor (LWR) was granted in the late 1970s. In 1989 the NRC issued 10 CFR Part 52 which is intended to serve as a framework for the licensing of future reactor designs. The NRC is currently reviewing four different future on {open_quotes}next-generation{close_quotes} reactor designs. Two of these designs are classified as evolutionary designs (modified versions of current generation LWRs) and two are advanced designs (reactors incorporating simplified designs and passive means for accident mitigation). These {open_quotes}next-generation{close_quotes} reactor designs incorporate many innovativemore » design features which are intended to maintain personnel doses ALARA and ensure that the annual average collective dose at these reactors does not exceed 100 person-rems (1 person-sievert) per year. This paper discusses some of the ALARA design features which are incorporated in the four {open_quotes}next-generation{close_quotes} reactor designs incorporate many innovative design features which are intended to maintain personnel doses ALARA and ensure that the annual average collective dose at these reactors does not exceed 100 person-rems (1 person-sievert) per year. This paper discusses some of the ALARA design features which are incorporated in the four {open_quotes}next-generation{close_quotes} reactor designs currently being reviewed by the NRC.« less

Early College Entrance in Australia

ERIC Educational Resources Information Center

Jung, Jae Yup; Young, Marie; Gross, Miraca U. M.

2015-01-01

Early college entry is an educational intervention that is being increasingly used in Australia. Following a review of the current Australian literature on early college entry, an overview is provided of the characteristics of, and the procedures associated with, one formal Australian early college entry program (the Early Admission for…

Diffraction of electrons at intermediate energies: The role of phonons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ascolani, H.; Zampieri, G.

1996-07-01

The intensity of electrons reflected {open_quote}{open_quote}elastically{close_quote}{close_quote} from crystalline surfaces presents two regimes: the low-energy or LEED regime ({lt}500 eV), in which the electrons are reflected along the Bragg directions, and the intermediate-energy or XPD/AED regime ({gt}500 eV), in which the maxima of intensity are along the main crystallographic axes. We present a model which explains this transition in terms of the excitation/absorption of phonons during the scattering. {copyright} {ital 1996 American Institute of Physics.}

Boundary reflection matrices for nonsimply laced affine Toda field theories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, J.D.

The boundary reflection matrices for nonsimply laced affine Toda field theories defined on a half line with the Neumann boundary condition are investigated. The boundary reflection matrices for some pairs of the models are evaluated up to one loop order by perturbation theory. Then the exact boundary reflection matrices which are consistent with the one loop result are found under the assumption of {open_quote}{open_quote}duality{close_quote}{close_quote} and tested against algebraic consistency such as the boundary bootstrap equation and boundary crossing-unitarity relation. {copyright} {ital 1996 The American Physical Society.}

The link between early onset drinking and early onset alcohol-impaired driving in young males.

PubMed

Zhang, Lening; Wieczorek, William F; Welte, John W

2014-05-01

Young drivers represent a disproportionate number of the individuals involved in alcohol-impaired driving. Although there is a known association between drinking and alcohol-impaired driving in young drivers, the link between early onset drinking and early onset alcohol-impaired driving has not been explored. The present study aimed to assess this link along with potentially confounding factors. The assessment used a proportional hazards model with data collected from the Buffalo Longitudinal Study of Young Men, a population-based sample of 625 males at aged 16-19. Controlling for the effects of potentially relevant confounds, the early onset of drinking was the most influential factor in predicting the early onset of alcohol-impaired driving. Race and the early onset of other forms of delinquency also played a significant role in the early onset of alcohol-impaired driving. Preventing an early start of drinking among adolescents may be the most critical factor to address in preventing an early start of alcohol-impaired driving.

76 FR 28252 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

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Wundt as chemist? A fresh look at his practice and theory of experimentation.

PubMed

Schmidgen, Henning

2003-01-01

Mid-19th-century chemistry constituted a practically and theoretically important resource for experimental psychology as conceived by Wilhelm Wundt (1832-1920). In the early 1850s, Wundt began working in Gustav Herth's private chemical laboratory in Heidelberg. The experimental work Wundt conducted under Herth's direction provided the practical model for the psychological methods advocated in Wundt's pioneering publication on visual perception in 1862. With respect to theory, Wundt relied on John Stuart Mill's System of Logic, a book often referring to the chemical writings by Justus Liebig. Wundt not only read and quoted Mill's logic but also was personally acquainted with its German translator, the former Liebig student Jacob Schiel. Thus, in various ways, chemistry influenced Wundt's early theory and practice of experiment.

Physiological processes during winter dormancy and their ecological significance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Havranek, W.M.; Tranquillini, W.

1995-07-01

Lengthy and severe winters require that trees in the forests of boreal and mountain zones undergo winter dormancy. Physiologically, a high resistance to subfreezing temperatures and concomitant dehydration are necessary. To accomplish this dormancy, both physiological and structural changes are needed at the cellular level that require induction by endogenous and photoperiodic control early in autumn. Endogenous rhythmicity promotes cold hardening in early autumn and the persistence of hardiness throughout the winter. Numerous physiological functions are maintained at a reduced level, or become completely inhibited during true winter dormancy. Winter hardiness also includes the capability to minimize water loss effectivelymore » when water uptake is severely impeded or impossible. Anatomical features such as tracheids act to minimize xylem embolism during frequent freeze-thaw cycles, and {open_quotes}crown{close_quotes} tissues enable buds to stay in a dehydrated and, thus, more resistant state during winter. Both these structural features are adaptations that contribute to the dominance of conifers in cold climates. Interestingly, deciduous tree species rather than evergreen conifers dominate in the most severe winter climates, although it is not clear whether limitations during winter, during the summer growth period, or during both are most limiting to conifer tree ecology. Additional work that evaluates the importance of winter and summer growth restriction, and their interaction, is needed before a comprehensive understanding of conifer tree ecophysiology will be possible.« less

Proactive investigation of hydrocarbons released into a linked groundwater-surfacewater hydrologic system: Chevron Estero Marine Terminal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tormey, D.; Waldron, J.; Culbertson, D.

When regulatory concern is high, it is critical to address potential ecological impacts early, and hence [open quotes]close the door[close quotes] on further unnecessary studies, as illustrated by the Chevron Estero Marine Terminal case study. Cutter stock (diesel-like hydrocarbons) leaked from a facility sump, reached the water table, and migrated laterally an unknown distance. Media reports led to heightened public and regulatory concern, and the information gap led to worst-case assumptions about the extent and impact of the release to the biota of a nearby creek (Toro Creek). Chevron undertook a rapid assessment with two goals: define the extent ofmore » cutter stock in soil and groundwater, and close the door on expensive biological studies of Toro Creek. The assessment consisted of installing a large number of small-diameter soil borings and temporary well points, monitor wells, and analyzing soil, groundwater, and hydraulic gradient. The information gap was very rapidly filled with the following comprehensive picture: (1) the cutter stock had mixed with heavy crude oil, was highly adsorptive to soil and practically insoluble in water; (2) the cutter stock had not reached Toro Creek; (3) Toro Creek is always a losing stream, hydraulically connected to groundwater beneath the Chevron facility; (4) the groundwater basin is isolated by bedrock boundaries. Early attention to Toro Creek and the Pacific Ocean, and open communication with concerned agencies effectively limited the investigation to soil and water.« less

Proactive investigation of hydrocarbons released into a linked groundwater-surfacewater hydrologic system: Chevron Estero Marine Terminal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tormey, D.; Waldron, J.; Culbertson, D.

When regulatory concern is high, it is critical to address potential ecological impacts early, and hence {open_quotes}close the door{close_quotes} on further unnecessary studies, as illustrated by the Chevron Estero Marine Terminal case study. Cutter stock (diesel-like hydrocarbons) leaked from a facility sump, reached the water table, and migrated laterally an unknown distance. Media reports led to heightened public and regulatory concern, and the information gap led to worst-case assumptions about the extent and impact of the release to the biota of a nearby creek (Toro Creek). Chevron undertook a rapid assessment with two goals: define the extent of cutter stockmore » in soil and groundwater, and close the door on expensive biological studies of Toro Creek. The assessment consisted of installing a large number of small-diameter soil borings and temporary well points, monitor wells, and analyzing soil, groundwater, and hydraulic gradient. The information gap was very rapidly filled with the following comprehensive picture: (1) the cutter stock had mixed with heavy crude oil, was highly adsorptive to soil and practically insoluble in water; (2) the cutter stock had not reached Toro Creek; (3) Toro Creek is always a losing stream, hydraulically connected to groundwater beneath the Chevron facility; (4) the groundwater basin is isolated by bedrock boundaries. Early attention to Toro Creek and the Pacific Ocean, and open communication with concerned agencies effectively limited the investigation to soil and water.« less

Cognitive Development in Early Readers.

ERIC Educational Resources Information Center

Briggs, Chari; Elkind, David

Some studies of early readers are discussed. It is pointed out that study of early readers has relevance for practical and theoretical issues in psychology and education. Of interest in this document are the following questions: (1) Are there any special talents or traits distinguishing early from non-early readers? (2) Do children who read early…

THE LINK BETWEEN EARLY ONSET DRINKING AND EARLY ONSET ALCOHOL-IMPAIRED DRIVING IN YOUNG MALES

PubMed Central

Zhang, Lening; Wieczorek, William F.; Welte, John W.

2014-01-01

Background Young drivers represent a disproportionate number of the individuals involved in alcohol-impaired driving. Although there is a known association between drinking and alcohol-impaired driving in young drivers, the link between early onset drinking and early onset alcohol-impaired driving has not been explored. Objectives The present study aimed to assess this link along with potentially confounding factors. Methods The assessment used a proportional hazards model with data collected from the Buffalo Longitudinal Study of Young Men, a population based sample of 625 males at ages of 16–19 years old. Results Controlling for the effects of potentially relevant confounds, the early onset of drinking was the most influential factor in predicting the early onset of alcohol-impaired driving. Race and the early onset of other forms of delinquency also played a significant role in the early onset of alcohol-impaired driving. Conclusion Preventing an early start of drinking among adolescents may be the most critical factor to address in preventing an early start of alcohol-impaired driving. PMID:24766089

Water key ingredient in Turkish farming

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aydin, M.

1995-12-31

Turkey, like most other Mediterranean countries, is an arid country, notes Mehmet Aydin, professor of soil science at Cukorova University in Adama, Turkey. And like most other Mediterranean countries, Aydin adds, Turkey is experiencing a population beam. In the past three decades, this increase in population has put a strain on the land. The boom, in fact, {open_quotes}has led to overgrazing, more intense cultivation, and greater harvest of shrubs and trees for firewood.{close_quotes} In 1987, the Turkish government launched the Southeastern Anatolian Development Project. Its goal is to bring irrigation and hydroelectric power to the area along the banks ofmore » the Euphrates and Tigris rivers. {open_quotes}When the project is complete, it will carry irrigation water to an estimated 4 million acres and create some 26 billion kilowatt-hours of electricity per year,{close_quotes} Aydin notes. The Southeastern Anatolian Development Project {open_quotes}will usher in an era of modern agriculture for Turkish farmers, one based on high-yield systems that are as sustainable as they are productive,{close_quotes} Aydin concludes.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, J.; Liu, C.; Koopman, W.J.

Ligation of the Fas cell-surface molecule induces apoptosis. Defective Fas-mediated apoptosis has been associated with spontaneous autoimmunity in mice. Using human Fas/Apo-1 cDNA as a probe, the authors have molecularly cloned and characterized the human Fas chromosomal gene. The gene consists of nine exons and spans more than 26 kilobases of DNA. The lengths of introns vary from > 14 kilobases at the 5` end of the gene to 152 base pairs upstream of the exon encoding the transmembrane domain. The domain structure of the human Fas is encoded by an exon or a set of exons. Primer extension analysismore » revealed three major transcription initiation sites. The promoter region lacked canonical {open_quotes}TATA{close_quotes} and {open_quotes}CAAT{close_quotes} boxes but was a {open_quotes}GC-rich{close_quotes} sequence, and contained consensus sequences for AP-1, GF-1, NY-Y, CP-2, EBP20, and c-myb. These data provide the first characterization of the human Fas gene and insight into its regulatory region. 54 refs., 3 figs., 1 tab.« less

Knowledge assistant: A sensor fusion framework for robotic environmental characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feddema, J.T.; Rivera, J.J.; Tucker, S.D.

1996-12-01

A prototype sensor fusion framework called the {open_quotes}Knowledge Assistant{close_quotes} has been developed and tested on a gantry robot at Sandia National Laboratories. This Knowledge Assistant guides the robot operator during the planning, execution, and post analysis stages of the characterization process. During the planning stage, the Knowledge Assistant suggests robot paths and speeds based on knowledge of sensors available and their physical characteristics. During execution, the Knowledge Assistant coordinates the collection of data through a data acquisition {open_quotes}specialist.{close_quotes} During execution and post analysis, the Knowledge Assistant sends raw data to other {open_quotes}specialists,{close_quotes} which include statistical pattern recognition software, a neuralmore » network, and model-based search software. After the specialists return their results, the Knowledge Assistant consolidates the information and returns a report to the robot control system where the sensed objects and their attributes (e.g. estimated dimensions, weight, material composition, etc.) are displayed in the world model. This paper highlights the major components of this system.« less

Knowledge assistant for robotic environmental characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feddema, J.; Rivera, J.; Tucker, S.

1996-08-01

A prototype sensor fusion framework called the {open_quotes}Knowledge Assistant{close_quotes} has been developed and tested on a gantry robot at Sandia National Laboratories. This Knowledge Assistant guides the robot operator during the planning, execution, and post analysis stages of the characterization process. During the planning stage, the Knowledge Assistant suggests robot paths and speeds based on knowledge of sensors available and their physical characteristics. During execution, the Knowledge Assistant coordinates the collection of data through a data acquisition {open_quotes}specialist.{close_quotes} During execution and postanalysis, the Knowledge Assistant sends raw data to other {open_quotes}specialists,{close_quotes} which include statistical pattern recognition software, a neural network,more » and model-based search software. After the specialists return their results, the Knowledge Assistant consolidates the information and returns a report to the robot control system where the sensed objects and their attributes (e.g., estimated dimensions, weight, material composition, etc.) are displayed in the world model. This report highlights the major components of this system.« less

Famines in Africa: is early warning early enough?

PubMed Central

Kim, Jeeyon Janet; Guha-Sapir, Debarati

2012-01-01

Following the second Sahelian famine in 1984–1985, major investments were made to establish Early Warning Systems. These systems help to ensure that timely warnings and vulnerability information are available to decision makers to anticipate and avert food crises. In the recent crisis in the Horn of Africa, alarming levels of acute malnutrition were documented from March 2010, and by August 2010, an impending food crisis was forecast. Despite these measures, the situation remained unrecognised, and further deteriorated causing malnutrition levels to grow in severity and scope. By the time the United Nations officially declared famine on 20 July 2011, and the humanitarian community sluggishly went into response mode, levels of malnutrition and mortality exceeded catastrophic levels. At this time, an estimated 11 million people were in desperate and immediate need for food. With warnings of food crises in the Sahel, South Sudan, and forecast of the drought returning to the Horn, there is an immediate need to institutionalize change in the health response during humanitarian emergencies. Early warning systems are only effective if they trigger an early response. PMID:22745628

Famines in Africa: is early warning early enough?

PubMed

Kim, Jeeyon Janet; Guha-Sapir, Debarati

2012-01-01

Following the second Sahelian famine in 1984-1985, major investments were made to establish Early Warning Systems. These systems help to ensure that timely warnings and vulnerability information are available to decision makers to anticipate and avert food crises. In the recent crisis in the Horn of Africa, alarming levels of acute malnutrition were documented from March 2010, and by August 2010, an impending food crisis was forecast. Despite these measures, the situation remained unrecognised, and further deteriorated causing malnutrition levels to grow in severity and scope. By the time the United Nations officially declared famine on 20 July 2011, and the humanitarian community sluggishly went into response mode, levels of malnutrition and mortality exceeded catastrophic levels. At this time, an estimated 11 million people were in desperate and immediate need for food. With warnings of food crises in the Sahel, South Sudan, and forecast of the drought returning to the Horn, there is an immediate need to institutionalize change in the health response during humanitarian emergencies. Early warning systems are only effective if they trigger an early response.

Employment and educational outcomes in early intervention programmes for early psychosis: a systematic review.

PubMed

Bond, G R; Drake, R E; Luciano, A

2015-10-01

Young adults with early psychosis want to pursue normal roles - education and employment. This paper summarises the empirical literature on the effectiveness of early intervention programmes for employment and education outcomes. We conducted a systematic review of employment/education outcomes for early intervention programmes, distinguishing three programme types: (1) those providing supported employment, (2) those providing unspecified vocational services and (3) those without vocational services. We summarised findings for 28 studies. Eleven studies evaluated early intervention programmes providing supported employment. In eight studies that reported employment outcomes separately from education outcomes, the employment rate during follow-up for supported employment patients was 49%, compared with 29% for patients receiving usual services. The two groups did not differ on enrolment in education. In four controlled studies, meta-analysis showed that the employment rate for supported employment participants was significantly higher than for control participants, odds ratio = 3.66 [1.93-6.93], p < 0.0001. Five studies (four descriptive and one quasi-experimental) of early intervention programmes evaluating unspecified vocational services were inconclusive. Twelve studies of early intervention programmes without vocational services were methodologically heterogeneous, using diverse methods for evaluating vocational/educational outcomes and precluding a satisfactory meta-analytic synthesis. Among studies with comparison groups, 7 of 11 (64%) reported significant vocational/education outcomes favouring early intervention over usual services. In early intervention programmes, supported employment moderately increases employment rates but not rates of enrolment in education. These improvements are in addition to the modest effects early programmes alone have on vocational/educational outcomes compared with usual services.

The Association between Early Conduct Problems and Early Marijuana Use in College Students

ERIC Educational Resources Information Center

Falls, Benjamin J.; Wish, Eric D.; Garnier, Laura M.; Caldeira, Kimberly M.; O'Grady, Kevin E.; Vincent, Kathryn B.; Arria, Amelia M.

2011-01-01

Early conduct problems have been linked to early marijuana use in adolescence. The present study examines this association in a sample of 1,076 college students that was divided into three groups: (1) early marijuana users (began marijuana use prior to age 15; N = 126), (2) late marijuana users (began marijuana use at or after age 15; N = 607),…

75 FR 5365 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... SPY and IWM as eligible to quote in $0.01 increments, regardless of premium value. The Exchange will... operative delay will allow the Exchange to commence quoting all series of IWM and SPY in increments of $0.01... Proposed Rule Change To Allow All SPY and IWM Options Series To Quote in Penny Increments January 27, 2010...

Respirators, internal dose, and Oyster Creek

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michal, R.

1996-06-01

This article looks at the experience of Oyster Creek in relaxing the requirements for the use of respirators in all facets of plant maintenance, on the overall dose received by plant maintenance personnel. For Roger Shaw, director of radiological controls for three years at GPU Nuclear Corporation`s Oyster Creek nuclear plant the correct dose balance is determined on a job-by-job basis: Does the job require a respirator, which is an effective means of decreasing worker inhalation of airborne radioactive particles? Will wearing a respirator slow down a worker, consequently increasing whole body radiation exposure by prolonging the time spent inmore » fields of high external radiation? How does respiratory protection affect worker safety and to what degree? While changes to the Nuclear Regulatory Commission`s 10CFR20 have updated the radiation protection requirements for the nuclear industry, certain of the revisions have been directed specifically at reducing worker dose, Shaw said. {open_quotes}It basically delineates that dose is dose,{close_quotes} Shaw said, {open_quotes}regardless of whether it is acquired externally or internally.{close_quotes} The revision of Part 20 changed the industry`s attitude toward internal dose, which had always been viewed negatively. {open_quotes}Internal dose was always seen as preventable by wearing respirators and by using engineering techniques such as ventilation control and decontamination,{close_quotes} Shaw said, {open_quotes}whereas external dose, although reduced where practical, was seen as a fact of the job.{close_quotes}« less

Department of Energy ALARA implementation guide. Response to the Health Physics Society

DOE Office of Scientific and Technical Information (OSTI.GOV)

Connelly, J.M.

1995-03-01

In the August 1993 Health Physics Society (HPS) newsletter, the HPS Scientific and Public Issues Committee published a Position Statement entitled {open_quotes}Radiation Protection of the Public and the Environment.{close_quotes}. In this article, this HPS committee made the statement that they were deeply concerned by the trend for agencies to incorporate the ALARA concept as a regulatory requirements, without providing specific guidance as to what it means and how to implement it consistently. The HPS position paper was in response to the DOE notice on proposed rulemaking for Title 10 Code of Federal Regulations Part 834, {open_quotes}Radiation Protection of the Publicmore » and the Environment{close_quotes} (10 CFR 834). In the notice of proposed rulemaking for 10 CFR 834, the Department of Energy (DOE) defined ALARA as follows: {open_quotes}As used in this part, ALARA is not a dose limit, but rather a process which has the objective of attaining doses as far below the applicable limit of this part as is reasonably achievable{close_quotes} (10 CFR 834.2, p. 16283 of the Federal Register). The HPS position paper continues, {open_quotes}The section goes on to elaborate on what is meant by a process without providing sufficient guidance to assure uniform applicability of the process.{close_quotes}. Although this concern is directed towards the ALARA process as it relates to the environment, the Office of Health, which is responsible for occupational workers, shares the same definition for ALARA.« less

Thermal and time-temperature index (TTI) patterns during geologic evolution of north and central Gulf of Mexico

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowrie, A.; Hamiter, R.; Fogarty, M.A.

1996-09-01

Regional thermal and Time-Temperature Index (TTI) contours were prepared for 12 dip paleo-tectonic reconstructions extending from central Arkansas to the central Gulf Basin. The first 9 reconstructions are based on back-stripping of Series-long sequences above the Louann Salt with the salt not restored. Additional reconstructions through Lower Jurassic set a geologic scenario prior to continental rifting. The reconstructions with salt not restored reveal a paleo-Sigsbee salt wedge, undergirding the Upper Jurassic to Pleistocene continental slope, has been a {open_quotes}permanent{close_quotes} ocean-side feature of the prograding margin, a salt-sediment geometry not in existent salt tectonic theories. Such a permanent and laterally migratingmore » {open_quotes}salt nose{close_quotes} provides an obstacle against which descending gravity-driven sediments can interact, creating reservoir-grade deposits against protruding salts features. The nose migration has left a lubricating layer of salt welds and other features. This salt-surrounded unit, beneath and downdip, may be termed a {open_quotes}salt-floored sub-basin{close_quotes} containing mostly {open_quotes}shallow{close_quotes} sediments of coastal plain, shelf, and slope genesis and growing through time. By Lower Cretaceous (131-96 mybp) times, the salt-floored basin updip from the then Sigsbee salt wedge was deep enough, approximately 5-7 km, that hydrocarbon maturation had begun. In the Upper Cretaceous (96-66 mybp), hydrocarbon maturation extended to sediments along flanks of the recently extinct mid-ocean ridge. From then to the present, ever more of the sedimentary volume has been subject to maturation.« less

Early Childhood Education.

ERIC Educational Resources Information Center

Elkind, David

In five sections, this paper explores dimensions of early childhood education: schooling generally construed as nonparental instruction in knowledge, values, and skills. Section 1 looks at some of the factors which have contributed to the rapid growth of early childhood education in modern times. Section 2 briefly highlights the contributions of…

Early Pregnancy Loss

MedlinePlus

... known pregnancies. What causes early pregnancy loss? About one half of cases of early pregnancy loss are caused by a ... do not show any signs of an infection, one option is to wait and let the ... may take longer in some cases. Another option is to take medication that helps ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huttrer, G.W.

This report summarizes the investigation and evaluation of several {open_quotes}compact{close_quotes} drill rigs which could be used for drilling geothermal production wells. Use of these smaller rigs would save money by reducing mobilization costs, fuel consumption, crew sizes, and environmental impact. Advantages and disadvantages of currently-manufactured rigs are identified, and desirable characteristics for the {open_quotes}ideal{close_quotes} compact rig are defined. The report includes a detailed cost estimate of a specific rig, and an evaluation of the cost/benefit ratio of using this rig. Industry contacts for further information are given.

Private sector cautious on Pemex reorganization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sissell, K.

1997-03-19

Private sector interest in the privatization of the petrochemical subsidiaries of Mexico`s state oil company Petroleos Mexicanos (Pemex) will hinge on the government`s decisions on minority ownership, says Raul Millares, president of Aniq, the Mexican chemical industry association. The murkiest issues are how the subsidiaries will be operated and what rights minority owners will have. {open_quotes}The question is who is going to manage the subsidiaries on a day-to-day basis,{close_quotes} says Millares. {open_quotes}There is a lot of doubt as to whether private companies will be able to get the flexibility they need.{close_quotes}

Early Retirement Payoff

ERIC Educational Resources Information Center

Fitzpatrick, Maria D.; Lovenheim, Michael F.

2014-01-01

As public budgets have grown tighter over the past decade, states and school districts have sought ways to control the growth of spending. One increasingly common strategy employed to rein in costs is to offer experienced teachers with high salaries financial incentives to retire early. Although early retirement incentive (ERI) programs have been…

Rethinking Early Education

ERIC Educational Resources Information Center

Celeste, Eric

2017-01-01

The National Association for the Education of Young Children (NAEYC) says in its current policy paper that, for high-quality early education to exist outside of tiny islands across the country, the following must be addressed: (1) teacher preparation; (2) ongoing professional learning; and (3) disparity in early education teacher pay. To achieve…

Biological aspects of early osteoarthritis.

PubMed

Madry, Henning; Luyten, Frank P; Facchini, Andrea

2012-03-01

Early OA primarily affects articular cartilage and involves the entire joint, including the subchondral bone, synovial membrane, menisci and periarticular structures. The aim of this review is to highlight the molecular basis and histopathological features of early OA. Selective review of literature. Risk factors for developing early OA include, but are not limited to, a genetic predisposition, mechanical factors such as axial malalignment, and aging. In early OA, the articular cartilage surface is progressively becoming discontinuous, showing fibrillation and vertical fissures that extend not deeper than into the mid-zone of the articular cartilage, reflective of OARSI grades 1.0-3.0. Early changes in the subchondral bone comprise a progressive increase in subchondral plate and subarticular spongiosa thickness. Early OA affects not only the articular cartilage and the subchondral bone but also other structures of the joint, such as the menisci, the synovial membrane, the joint capsule, ligaments, muscles and the infrapatellar fat pad. Genetic markers or marker combinations may become useful in the future to identify early OA and patients at risk. The high socioeconomic impact of OA suggests that a better insight into the mechanisms of early OA may be a key to develop more targeted reconstructive therapies at this first stage of the disease. Systematic review, Level II.

Eco-Early Childhood Education: A New Paradigm of Early Childhood Education in South Korea

ERIC Educational Resources Information Center

Kim, Eunju; Lim, Jaetack

2007-01-01

In the early 1990s, university faculty members, early childhood educators, and preschool teachers in South Korea created a new paradigm for education. Eco-early childhood education uses an ecological point of view to reform existing child-centered education. This perspective proposes moving from child- to life-centered, individual- to…

Course of Disinhibited Social Engagement Disorder From Early Childhood to Early Adolescence.

PubMed

Guyon-Harris, Katherine L; Humphreys, Kathryn L; Fox, Nathan A; Nelson, Charles A; Zeanah, Charles H

2018-05-01

Disinhibited social engagement disorder (DSED) is poorly understood beyond early childhood. The course of DSED signs in a sample of children who experienced severe, early deprivation from early childhood to early adolescence was examined using variable-centered (linear mixed modeling) and person-centered (growth mixture modeling) approaches. The study included 124 children with a history of institutional care from a randomized controlled trial of foster care as an alternative to institutional care and 69 community comparison children matched by age and sex. DSED signs were assessed at baseline (mean age 22 months), 30, 42, and 54 months of age, and 8 and 12 years of age using a validated caregiver report of disturbed attachment behavior. Variable-centered analyses based on intent-to-treat groups indicated that signs of DSED decreased sharply for children randomized to foster care and decreased slightly but remained high for children randomized to care as usual. Person-centered analyses showed 4 profiles (i.e., elevated, persistent modest, early decreasing, and minimal). Elevated and persistent modest courses were associated with greater placement disruptions (F 3,99  = 4.29, p = .007, partial eta-squared [η 2 ] = 0.12), older age at placement into foster care (F 3,56  = 3.41, p < .05, partial η 2  = 0.16), and more time in institutional care (F 3,115  = 11.91, p < .001, partial η 2  = 0.24) compared with decreasing and minimal courses. Early and sustained placement into families after deprivation is associated with minimal or decreasing signs of DSED across development. Shortening the amount of time children spend in institutions and preserving placements could help decrease signs of DSED into early adolescence in previously institutionalized children. Copyright © 2018 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

Leadership Competencies in U.S. Early Intervention/Early Childhood Special Education Service Systems: A National Survey

ERIC Educational Resources Information Center

Bruns, Deborah A.; LaRocco, Diana J.; Sharp, Olga L.; Sopko, Kim Moherek

2017-01-01

In 2015, the Division for Early Childhood of the Council for Exceptional Children released a position statement on leadership in early intervention and early childhood special education (EI/ECSE). Division for Early Childhood emphasized the importance of developing and supporting high-quality leadership within and across all levels of EI/ECSE…

Early Numeracy Assessment: The Development of the Preschool Early Numeracy Scales

ERIC Educational Resources Information Center

Purpura, David J.; Lonigan, Christopher J.

2015-01-01

Research Findings: The focus of this study was to construct and validate 12 brief early numeracy assessment tasks that measure the skills and concepts identified as key to early mathematics development by the National Council of Teachers of Mathematics (2006) and the National Mathematics Advisory Panel (2008)-as well as critical developmental…

78 FR 39346 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-01

... collected, unless a Quote Exhaust has occurred, in which case the Quote Exhaust process in Rule 1082(a)(ii.... * * * * * Rule 1082 Firm Quotations (a)(i)-(ii)(B)(3)(g)(v) No change. (vi) If, after trading at the Phlx and/or... occurred, in which case the Quote Exhaust process in Rule 1082(a)(ii)(B)(3) will ensue,\\6\\ triggering a new...

Timing of Orphanhood, Early Sexual Debut, and Early Marriage in Four Sub-Saharan African Countries

PubMed Central

Chae, Sophia

2014-01-01

According to a growing body of literature, some orphans are at heightened risk of early sexual debut and early marriage. This study examines a rarely explored aspect of orphanhood: the timing and type of parental death and their relationship to these outcomes. The study also explores whether education mediates orphans’ risk of early sexual initiation and early marriage. The data are drawn from the 2004 National Survey of Adolescents, which includes interviews with 12–19-year-old adolescents in Burkina Faso, Ghana, Malawi, and Uganda. Results from discrete-time event history analysis indicate that female double orphans, regardless of timing of orphanhood, have greater odds of early sexual debut than do nonorphans. Education explains little of their increased risk. In contrast, male orphans of any type reveal no increased vulnerability to early sexual debut. Uganda is the only country where female orphans, specifically double orphans and those who are paternal orphans before age 10, have greater odds of early marriage, with education accounting for a small portion of the risk. PMID:23719999

Early Childhood Predictors of Low-Income Boys’ Pathways to Antisocial Behavior in Childhood, Adolescence, and Early Adulthood

PubMed Central

Shaw, Daniel S.; Gilliam, Mary

2016-01-01

Guided by a bridging model of pathways leading to low-income boys’ early-starting and persistent trajectories of antisocial behavior, the current paper reviews evidence supporting the model from early childhood through early adulthood. Using primarily a cohort of 310 low-income boys of families recruited from WIC centers in a large metropolitan area followed from infancy to early adulthood, and smaller cohorts of boys and girls followed through early childhood, we provide evidence supporting the critical role of parenting, maternal depression, and other proximal family risk factors in early childhood that are prospectively linked to trajectories of parent-reported conduct problems in early and middle childhood, youth-reported antisocial behavior during adolescence and early adulthood, as well as court-reported violent offending in adolescence. The findings are discussed in terms of the need to identify at-risk boys in early childhood and methods and platforms for engaging families in health care settings not previously used to implement preventive mental health services. PMID:28026042

Early cosmology constrained

NASA Astrophysics Data System (ADS)

Verde, Licia; Bellini, Emilio; Pigozzo, Cassio; Heavens, Alan F.; Jimenez, Raul

2017-04-01

We investigate our knowledge of early universe cosmology by exploring how much additional energy density can be placed in different components beyond those in the ΛCDM model. To do this we use a method to separate early- and late-universe information enclosed in observational data, thus markedly reducing the model-dependency of the conclusions. We find that the 95% credibility regions for extra energy components of the early universe at recombination are: non-accelerating additional fluid density parameter ΩMR < 0.006 and extra radiation parameterised as extra effective neutrino species 2.3 < Neff < 3.2 when imposing flatness. Our constraints thus show that even when analyzing the data in this largely model-independent way, the possibility of hiding extra energy components beyond ΛCDM in the early universe is seriously constrained by current observations. We also find that the standard ruler, the sound horizon at radiation drag, can be well determined in a way that does not depend on late-time Universe assumptions, but depends strongly on early-time physics and in particular on additional components that behave like radiation. We find that the standard ruler length determined in this way is rs = 147.4 ± 0.7 Mpc if the radiation and neutrino components are standard, but the uncertainty increases by an order of magnitude when non-standard dark radiation components are allowed, to rs = 150 ± 5 Mpc.

Early cosmology constrained

DOE Office of Scientific and Technical Information (OSTI.GOV)

Verde, Licia; Jimenez, Raul; Bellini, Emilio

We investigate our knowledge of early universe cosmology by exploring how much additional energy density can be placed in different components beyond those in the ΛCDM model. To do this we use a method to separate early- and late-universe information enclosed in observational data, thus markedly reducing the model-dependency of the conclusions. We find that the 95% credibility regions for extra energy components of the early universe at recombination are: non-accelerating additional fluid density parameter Ω{sub MR} < 0.006 and extra radiation parameterised as extra effective neutrino species 2.3 < N {sub eff} < 3.2 when imposing flatness. Our constraintsmore » thus show that even when analyzing the data in this largely model-independent way, the possibility of hiding extra energy components beyond ΛCDM in the early universe is seriously constrained by current observations. We also find that the standard ruler, the sound horizon at radiation drag, can be well determined in a way that does not depend on late-time Universe assumptions, but depends strongly on early-time physics and in particular on additional components that behave like radiation. We find that the standard ruler length determined in this way is r {sub s} = 147.4 ± 0.7 Mpc if the radiation and neutrino components are standard, but the uncertainty increases by an order of magnitude when non-standard dark radiation components are allowed, to r {sub s} = 150 ± 5 Mpc.« less

A new approach to fracture modelling in reservoirs using deterministic, genetic and statistical models of fracture growth

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rawnsley, K.; Swaby, P.

1996-08-01

It is increasingly acknowledged that in order to understand and forecast the behavior of fracture influenced reservoirs we must attempt to reproduce the fracture system geometry and use this as a basis for fluid flow calculation. This article aims to present a recently developed fracture modelling prototype designed specifically for use in hydrocarbon reservoir environments. The prototype {open_quotes}FRAME{close_quotes} (FRActure Modelling Environment) aims to provide a tool which will allow the generation of realistic 3D fracture systems within a reservoir model, constrained to the known geology of the reservoir by both mechanical and statistical considerations, and which can be used asmore » a basis for fluid flow calculation. Two newly developed modelling techniques are used. The first is an interactive tool which allows complex fault surfaces and their associated deformations to be reproduced. The second is a {open_quotes}genetic{close_quotes} model which grows fracture patterns from seeds using conceptual models of fracture development. The user defines the mechanical input and can retrieve all the statistics of the growing fractures to allow comparison to assumed statistical distributions for the reservoir fractures. Input parameters include growth rate, fracture interaction characteristics, orientation maps and density maps. More traditional statistical stochastic fracture models are also incorporated. FRAME is designed to allow the geologist to input hard or soft data including seismically defined surfaces, well fractures, outcrop models, analogue or numerical mechanical models or geological {open_quotes}feeling{close_quotes}. The geologist is not restricted to {open_quotes}a priori{close_quotes} models of fracture patterns that may not correspond to the data.« less

Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol.

PubMed

Eaton, Megan M; Germann, Allison L; Arora, Ruby; Cao, Lily Q; Gao, Xiaoyi; Shin, Daniel J; Wu, Albert; Chiara, David C; Cohen, Jonathan B; Steinbach, Joe Henry; Evers, Alex S; Akk, Gustav

2016-01-01

Propofol is a sedative agent that at clinical concentrations acts by allosterically activating or potentiating the γ-aminobutyric acid type A (GABAA) receptor. Mutational, modeling, and photolabeling studies with propofol and its analogues have identified potential interaction sites in the transmembrane domain of the receptor. At the &quot;+&quot; of the β subunit, in the β-α interface, meta-azipropofol labels the M286 residue in the third transmembrane domain. Substitution of this residue with tryptophan results in loss of potentiation by propofol. At the &quot;-&quot; side of the β subunit, in the α-β interface (or β-β interface, in the case of homomeric β receptors), ortho-propofol diazirine labels the H267 residue in the second transmembrane domain. Structural modeling indicates that the β(H267) residue lines a cavity that docks propofol with favorable interaction energy. We used two-electrode voltage clamp to determine the functional effects of mutations to the &quot;+"; and &quot;-"; sides of the β subunit on activation of the α1β3 GABAA receptor by propofol. We found that while the individual mutations had a small effect, the combination of the M286W mutation with tryptophan mutations of selected residues at the α-β interface leads to strong reduction in gating efficacy for propofol. We conclude that α1β3 GABAA receptors can be activated by propofol interactions with the β-β, α-β, and β-α interfaces, where distinct, non-equivalent regions control channel gating. Any interface can mediate activation, hence substitutions at all interfaces are required for loss of activation by propofol.

Early Practicum Experiences: Preservice Early Childhood Students' Perceptions and Sense of Efficacy

ERIC Educational Resources Information Center

Van Schagen Johnson, Amy; La Paro, Karen M.; Crosby, Danielle A.

2017-01-01

The current study explored early practicum experiences (those occurring before student teaching) in an early childhood birth to kindergarten teacher education program. Undergraduates enrolled in practicum courses completed questionnaires about their overall practicum experience including: socio-emotional components (their perceived fit with their…

Redefining early gastric cancer.

PubMed

Barreto, Savio G; Windsor, John A

2016-01-01

The problem is that current definitions of early gastric cancer allow the inclusion of regional lymph node metastases. The increasing use of endoscopic submucosal dissection to treat early gastric cancer is a concern because regional lymph nodes are not addressed. The aim of the study was thus to critically evaluate current evidence with regard to tumour-specific factors associated with lymph node metastases in "early gastric cancer" to develop a more precise definition and improve clinical management. A systematic and comprehensive search of major reference databases (MEDLINE, EMBASE, PubMed and the Cochrane Library) was undertaken using a combination of text words "early gastric cancer", "lymph node metastasis", "factors", "endoscopy", "surgery", "lymphadenectomy" "mucosa", "submucosa", "lymphovascular invasion", "differentiated", "undifferentiated" and "ulcer". All available publications that described tumour-related factors associated with lymph node metastases in early gastric cancer were included. The initial search yielded 1494 studies, of which 42 studies were included in the final analysis. Over time, the definition of early gastric cancer has broadened and the indications for endoscopic treatment have widened. The mean frequency of lymph node metastases increased on the basis of depth of infiltration (mucosa 6% vs. submucosa 28%), presence of lymphovascular invasion (absence 9% vs. presence 53%), tumour differentiation (differentiated 13% vs. undifferentiated 34%) and macroscopic type (elevated 13% vs. flat 26%) and tumour diameter (≤2 cm 8% vs. >2 cm 25%). There is a need to re-examine the diagnosis and staging of early gastric cancer to ensure that patients with one or more identifiable risk factor for lymph node metastases are not denied appropriate chemotherapy and surgical resection.

Environmental, health, and safety issues for the petroleum geologist

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mathis, R.E.

1993-09-01

As the oil and gas industry moves toward the twenty-first century, professional within the industry must adjust to changes placed upon them from within and without. The role of the geologist is changing, as is the focal point of attention. Environmental issues require scrutiny of those zones once passed by with little or no interest while exploring for oil and gas reservoirs at deeper and deeper horizons; shallow zones of fresh or usable water are now often the main focus of attention. Has my training prepared me for being the company [open quotes]hydrologist[close quotes] or [open quotes]environmental expert[close quotes] Whatmore » does this new role mean for me Am I to be the [open quotes]Designated Jailee[close quotes] What should I know Environmental Assessment, site characterization, permissible exposure limit, time weighted average, and like terms are new to the ears of most petroleum geologists. These and other environmental health and safety terms impact the profession. What geologists may be expected to do in regard to them are issues of major concern. This paper will try to answer these questions and more.« less

In-plant management of hazardous waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hall, M.W.; Howell, W.L. Jr.

1995-12-31

One of the earliest sustainable technologies for the management of hazardous industrial wastes, and one of the most successful, is {open_quotes}In-Plant Control{close_quotes} Waste elimination, reuse and/or minimization can encourage improved utilization of resources, decreased environmental degradation and increased profits at individual industrial product ion sites, or within an industry. For new facilities and industries, putting such programs in place is relatively easy. Experience has shown, however, that this may be more difficult to initiate in existing facilities, especially in older and heavier industries. This task can be made easier by promoting a mutually respectful partnership between production and environmental interestsmore » within the facility or industry. This permits {open_quotes}common sense{close_quotes} thinking and a cooperative, proactive strategy for securing an appropriate balance between economic growth, environmental protection and social responsibility. Case studies are presented wherein a phased, incremental in-plant system for waste management was developed and employed to good effect, using a model that entailed {open_quotes}Consciousness, Commitment, Training, Recognition, Re-engineering and Continuous Improvement{close_quotes} to promote waste minimization or elimination.« less

Routine inspection effort required for verification of a nuclear material production cutoff convention

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dougherty, D.; Fainberg, A.; Sanborn, J.

On 27 September 1993, President Clinton proposed {open_quotes}... a multilateral convention prohibiting the production of highly enriched uranium or plutonium for nuclear explosives purposes or outside of international safeguards.{close_quotes} The UN General Assembly subsequently adopted a resolution recommending negotiation of a non-discriminatory, multilateral, and internationally and effectively verifiable treaty (hereinafter referred to as {open_quotes}the Cutoff Convention{close_quotes}) banning the production of fissile material for nuclear weapons. The matter is now on the agenda of the Conference on Disarmament, although not yet under negotiation. This accord would, in effect, place all fissile material (defined as highly enriched uranium and plutonium) produced aftermore » entry into force (EIF) of the accord under international safeguards. {open_quotes}Production{close_quotes} would mean separation of the material in question from radioactive fission products, as in spent fuel reprocessing, or enrichment of uranium above the 20% level, which defines highly enriched uranium (HEU). Facilities where such production could occur would be safeguarded to verify that either such production is not occurring or that all material produced at these facilities is maintained under safeguards.« less

Long-term predictions using natural analogues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ewing, R.C.

1995-09-01

One of the unique and scientifically most challenging aspects of nuclear waste isolation is the extrapolation of short-term laboratory data (hours to years) to the long time periods (10{sup 3}-10{sup 5} years) required by regulatory agencies for performance assessment. The direct validation of these extrapolations is not possible, but methods must be developed to demonstrate compliance with government regulations and to satisfy the lay public that there is a demonstrable and reasonable basis for accepting the long-term extrapolations. Natural systems (e.g., {open_quotes}natural analogues{close_quotes}) provide perhaps the only means of partial {open_quotes}validation,{close_quotes} as well as data that may be used directlymore » in the models that are used in the extrapolation. Natural systems provide data on very large spatial (nm to km) and temporal (10{sup 3}-10{sup 8} years) scales and in highly complex terranes in which unknown synergisms may affect radionuclide migration. This paper reviews the application (and most importantly, the limitations) of data from natural analogue systems to the {open_quotes}validation{close_quotes} of performance assessments.« less

The anaerobic digestion process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rivard, C.J.; Boone, D.R.

1996-01-01

The microbial process of converting organic matter into methane and carbon dioxide is so complex that anaerobic digesters have long been treated as {open_quotes}black boxes.{close_quotes} Research into this process during the past few decades has gradually unraveled this complexity, but many questions remain. The major biochemical reactions for forming methane by methanogens are largely understood, and evolutionary studies indicate that these microbes are as different from bacteria as they are from plants and animals. In anaerobic digesters, methanogens are at the terminus of a metabolic web, in which the reactions of myriads of other microbes produce a very limited rangemore » of compounds - mainly acetate, hydrogen, and formate - on which the methanogens grow and from which they form methane. {open_quotes}Interspecies hydrogen-transfer{close_quotes} and {open_quotes}interspecies formate-transfer{close_quotes} are major mechanisms by which methanogens obtain their substrates and by which volatile fatty acids are degraded. Present understanding of these reactions and other complex interactions among the bacteria involved in anaerobic digestion is only now to the point where anaerobic digesters need no longer be treated as black boxes.« less

Panel urges cloning ethics boards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marshall, E.

1997-01-03

A 7-month review of the system that guides U.S. policy on the ethical, legal, and social issues (ELSI) of the Human Genome Project has concluded that it is time for a radical overhaul. A report completed last month recommends that a high-level policy board be created in the office of the Secretary of Health and Human Services to help develop policies on such sensitive issues as genetic privacy, antidiscrimination legislation, public education on genetic risks, and the regulation of genetic testing. If accepted, the proposal-from a review panel chaired by attorney Mark Rothstein of the University of Houston and geneticistmore » M. Anne Spence of the University of California, Irvine-would create a new panel of 15 to 18 members to serve as {open_quotes}a public forum for discussion of ... critical issues.{close_quotes} This panel would replace the current advisory body, known as the ELSI Working Group, and end what the report calls a {open_quotes}discordance{close_quotes} between the broad scope of the Working Group and the {open_quotes}very limited focus{close_quotes} of the research program under which it operates.« less

Early psychosis workforce development: Core competencies for mental health professionals working in the early psychosis field.

PubMed

Osman, Helen; Jorm, Anthony F; Killackey, Eoin; Francey, Shona; Mulcahy, Dianne

2017-08-09

The aim of this study was to identify the core competencies required of mental health professionals working in the early psychosis field, which could function as an evidence-based tool to support the early psychosis workforce and in turn assist early psychosis service implementation and strengthen early psychosis model fidelity. The Delphi method was used to establish expert consensus on the core competencies. In the first stage, a systematic literature search was conducted to generate competency items. In the second stage, a panel consisting of expert early psychosis clinicians from around the world was formed. Panel members then rated each of the competency items on how essential they are to the clinical practice of all early psychosis clinicians. In total, 1023 pieces of literature including textbooks, journal articles and grey literature were reviewed. A final 542 competency items were identified for inclusion in the questionnaire. A total of 63 early psychosis experts participated in 3 rating rounds. Of the 542 competency items, 242 were endorsed as the required core competencies. There were 29 competency items that were endorsed by 62 or more experts, and these may be considered the foundational competencies for early psychosis practice. The study generated a set of core competencies that provide a common language for early psychosis clinicians across professional disciplines and country of practice, and potentially are a useful professional resource to support early psychosis workforce development and service reform. © 2017 John Wiley & Sons Australia, Ltd.

Detection of algorithmic trading

NASA Astrophysics Data System (ADS)

Bogoev, Dimitar; Karam, Arzé

2017-10-01

We develop a new approach to reflect the behavior of algorithmic traders. Specifically, we provide an analytical and tractable way to infer patterns of quote volatility and price momentum consistent with different types of strategies employed by algorithmic traders, and we propose two ratios to quantify these patterns. Quote volatility ratio is based on the rate of oscillation of the best ask and best bid quotes over an extremely short period of time; whereas price momentum ratio is based on identifying patterns of rapid upward or downward movement in prices. The two ratios are evaluated across several asset classes. We further run a two-stage Artificial Neural Network experiment on the quote volatility ratio; the first stage is used to detect the quote volatility patterns resulting from algorithmic activity, while the second is used to validate the quality of signal detection provided by our measure.

Early childhood predictors of early onset of smoking: a birth prospective study.

PubMed

Hayatbakhsh, Reza; Mamun, Abdullah A; Williams, Gail M; O'Callaghan, Michael J; Najman, Jake M

2013-10-01

Early onset of smoking is associated with subsequent abuse of other substances and development of negative health outcomes. This study aimed to examine early life predictors of onset of smoking in an Australian young cohort. Data were from the Mater Hospital and University of Queensland Study of Pregnancy (MUSP), a population-based prospective birth cohort study (1981-2012). The present study is based on a cohort of 3714 young adults who self-reported smoking status and age of onset of smoking at the 21-year follow-up. Of these, data were available for 3039 on early childhood factors collected between the baseline and 14-year follow-up of the study. Of 3714 young adults, 49.6% (49.9% males and 49.3% females) reported having ever smoked cigarettes. For those who had ever smoked, mean and median ages at first smoke were 15.5 and 16.0years, respectively. In multivariate Cox proportional hazard analysis mother's education, change in maternal marital status, maternal cigarette smoking and alcohol consumption, maternal depression and child externalizing when the child was 5years statistically significantly predicted early onset of smoking. The data suggest that individuals exposed to personal and environmental risk factors during the early stage of childhood are at increased risk of initiation to cigarette smoking at an earlier age. Identification of the pathways of association between these early life factors and initiation to cigarette smoking may help reduce risk of tobacco smoking in adolescents and its adverse consequences. Copyright © 2013 Elsevier Ltd. All rights reserved.

Lifting the veil.

PubMed

Sorrel, Amy Lynn

2014-07-01

As governments and employers look for ways to curb growing health care costs, and as patients bear a higher share of their medical bills, policymakers in Texas and beyond increasingly target physicians in their efforts to unveil health care prices. They couch such &quot;price transparency&quot; as a way to help patients make more informed health care decisions. But Texas Medical Association's Board of Trustees member Gary W. Floyd, MD, of Fort Worth, cautions that for a complex health care payment system, coupled with individual patients' complex needs, coming up with a so-called &quot;sticker price&quot; is not as simple as it seems.

Wholesale bakeries: A small-business guide. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Commercial baking is thought to be one of the world`s oldest industries, with evidence of commercial bakeries dating back to the Egyptians. In the late 19th century, technological innovations such as the development of {open_quotes}tame{close_quotes} yeast and the mechanization of bread kneading enabled mass production of baked goods. As a result, larger {open_quotes}wholesale{close_quotes} baking facilities began to replace smaller local bakeries. Today, there are over 3000 wholesale bakeries across the United States. This report is intended to provide information on the bakery business from the perspective of processes, issues, and challenges faced, including energy consumption of electrically driven equipment.

Beyond Developmentalism? Early Childhood Teachers' Understandings of Multiage Grouping in Early Childhood Education and Care

ERIC Educational Resources Information Center

Edwards, Susan; Blaise, Mindy; Hammer, Marie

2009-01-01

Postdevelopmental perspectives in early childhood education and care increasingly reference alternative ways of understanding learning, growth and development in early learning. Drawing on these ideas, this paper examines research findings which focused on early childhood teachers' understandings of multiage grouping. The findings suggested that…

Early Educational Intervention, Early Cumulative Risk, and the Early Home Environment as Predictors of Young Adult Outcomes Within a High-Risk Sample

PubMed Central

Pungello, Elizabeth P.; Kainz, Kirsten; Burchinal, Margaret; Wasik, Barbara H.; Sparling, Joseph J.; Ramey, Craig T.; Campbell, Frances A.

2009-01-01

The extent to which early educational intervention, early cumulative risk, and the early home environment were associated with young adult outcomes was investigated in a sample of 139 young adults (age 21) from high-risk families enrolled in randomized trials of early intervention. Positive effects of treatment were found for education attainment, attending college, and skilled employment; negative effects of risk were found for education attainment, graduating high school, being employed and avoiding teen parenthood. The home mediated the effects of risk for graduating high school, but not being employed or teen parenthood. Evidence for moderated mediation was found for educational attainment; the home mediated the association between risk and educational attainment for the control group, but not the treated group. PMID:20331676

Evaluation of Young Children for Early Intervention and Early Childhood Special Education.

ERIC Educational Resources Information Center

Allen, Diana

This technical assistance document provides guidelines for child assessment and eligibility determination for early intervention and early childhood special education programs in Oregon. An overview of the assessment process explains screening, eligibility evaluation, and assessment for the Individual Family Service Plan (IFSP). Legal requirements…

EARLY CHILDHOOD PREDICTORS OF LOW-INCOME BOYS' PATHWAYS TO ANTISOCIAL BEHAVIOR IN CHILDHOOD, ADOLESCENCE, AND EARLY ADULTHOOD.

PubMed

Shaw, Daniel S; Gilliam, Mary

2017-01-01

Guided by a bridging model of pathways leading to low-income boys' early starting and persistent trajectories of antisocial behavior, the current article reviews evidence supporting the model from early childhood through early adulthood. Using primarily a cohort of 310 low-income boys of families recruited from Women, Infants, and Children Nutrition Supplement centers in a large metropolitan area followed from infancy to early adulthood and a smaller cohort of boys and girls followed through early childhood, we provide evidence supporting the critical role of parenting, maternal depression, and other proximal family risk factors in early childhood that are prospectively linked to trajectories of parent-reported conduct problems in early and middle childhood, youth-reported antisocial behavior during adolescence and early adulthood, and court-reported violent offending in adolescence. The findings are discussed in terms of the need to identify at-risk boys in early childhood and methods and platforms for engaging families in healthcare settings not previously used to implement preventive mental health services. © 2016 Michigan Association for Infant Mental Health.

Early Reading and Concrete Operations.

ERIC Educational Resources Information Center

Polk, Cindy L. Howes; Goldstein, David

1980-01-01

Indicated that early readers are more likely to be advanced in cognitive development than are nonearly-reading peers. After one year of formal reading instruction, early readers maintained their advantage in reading achievement. Measures of concrete operations were found to predict reading achievement for early and nonearly readers. (Author/DB)

The Effectiveness of Early Intervention.

ERIC Educational Resources Information Center

Guralnick, Michael J., Ed.

This book reviews research on the effectiveness of early intervention for children with disabilities or who are at risk. Program factors for children at risk and with disabilities, the effects of early intervention on different types of disabilities, and the outcomes of early intervention are explored. Chapters include: "Second-Generation Research…

Early Rockets

NASA Image and Video Library

2004-04-15

During the 19th century, rocket enthusiasts and inventors began to appear in almost every country. Some people thought these early rocket pioneers were geniuses, and others thought they were crazy. Claude Ruggieri, an Italian living in Paris, apparently rocketed small animals into space as early as 1806. The payloads were recovered by parachute. As depicted here by artist Larry Toschik, French authorities were not always impressed with rocket research. They halted Ruggieri's plans to launch a small boy using a rocket cluster. (Reproduced from a drawing by Larry Toschik and presented here courtesy of the artist and Motorola Inc.)

Individual differences in early adolescents' latent trait cortisol: Interaction of early adversity and 5-HTTLPR.

PubMed

Chen, Frances R; Stroud, Catherine B; Vrshek-Schallhorn, Suzanne; Doane, Leah D; Granger, Douglas A

2017-10-01

The present study aimed to examine the interaction of 5-HTTLPR and early adversity on trait-like levels of cortisol. A community sample of 117 early adolescent girls (M age=12.39years) provided DNA samples for 5-HTTLPR genotyping, and saliva samples for assessing cortisol 3 times a day (waking, 30min post-waking, and bedtime) over a three-day period. Latent trait cortisol (LTC) was modeled using the first 2 samples of each day. Early adversity was assessed with objective contextual stress interviews with adolescents and their mothers. A significant 5-HTTLPR×early adversity interaction indicated that greater early adversity was associated with lower LTC levels, but only among individuals with either L/L or S/L genotype. Findings suggest that serotonergic genetic variation may influence the impact of early adversity on individual differences in HPA-axis regulation. Future research should explore whether this interaction contributes to the development of psychopathology through HPA axis functioning. Copyright © 2017 Elsevier B.V. All rights reserved.

Clarifying Parent-Child Reciprocities during Early Childhood: The Early Childhood Coercion Model

ERIC Educational Resources Information Center

Scaramella, Laura V.; Leve, Leslie D.

2004-01-01

Consistent with existing theory, the quality of parent-child interactions during early childhood affects children's social relationships and behavioral adjustment during middle childhood and adolescence. Harsh parenting and a propensity toward emotional overarousal interact very early in life to affect risk for later conduct problems. Less…

Risk of early surgery for Crohn's disease: implications for early treatment strategies.

PubMed

Sands, Bruce E; Arsenault, Joanne E; Rosen, Michael J; Alsahli, Mazen; Bailen, Laurence; Banks, Peter; Bensen, Steven; Bousvaros, Athos; Cave, David; Cooley, Jeffrey S; Cooper, Herbert L; Edwards, Susan T; Farrell, Richard J; Griffin, Michael J; Hay, David W; John, Alex; Lidofsky, Sheldon; Olans, Lori B; Peppercorn, Mark A; Rothstein, Richard I; Roy, Michael A; Saletta, Michael J; Shah, Samir A; Warner, Andrew S; Wolf, Jacqueline L; Vecchio, James; Winter, Harland S; Zawacki, John K

2003-12-01

In this study we aimed to define the rate of early surgery for Crohn's disease and to identify risk factors associated with early surgery as a basis for subsequent studies of early intervention in Crohn's disease. We assembled a retrospective cohort of patients with Crohn's disease diagnosed between 1991 and 1997 and followed for at least 3 yr, who were identified in 16 community and referral-based practices in New England. Chart review was performed for each patient. Details of baseline demographic and disease features were recorded. Surgical history including date of surgery, indication, and procedure were also noted. Risk factors for early surgery (defined as major surgery for Crohn's disease within 3 yr of diagnosis, exclusive of major surgery at time of diagnosis) were identified by univariate analysis. Multiple logistic regression was used to identify independent risk factors. Of 345 eligible patients, 69 (20.1%) required surgery within 3 yr of diagnosis, excluding the 14 patients (4.1%) who had major surgery at the time of diagnosis. Overall, the interval between diagnosis and surgery was short; one half of all patients who required surgery underwent operation within 6 months of diagnosis. Risk factors identified by univariate analysis as significantly associated with early surgery included the following: smoking; disease of small bowel without colonic involvement; nausea and vomiting or abdominal pain on presentation; neutrophil count; and steroid use in the first 6 months. Disease localized to the colon only, blood in the stool, use of 5-aminosalicylate, and lymphocyte count were inversely associated with risk of early surgery. Logistic regression confirmed independent associations with smoking as a positive risk factor and involvement of colon without small bowel as a negative risk factor for early surgery. The rate of surgery is high in the first 3 yr after diagnosis of Crohn's disease, particularly in the first 6 months. These results suggest that

Implementing Obstetric Early Warning Systems.

PubMed

Friedman, Alexander M; Campbell, Mary L; Kline, Carolyn R; Wiesner, Suzanne; D'Alton, Mary E; Shields, Laurence E

2018-04-01

Severe maternal morbidity and mortality are often preventable and obstetric early warning systems that alert care providers of potential impending critical illness may improve maternal safety. While literature on outcomes and test characteristics of maternal early warning systems is evolving, there is limited guidance on implementation. Given current interest in early warning systems and their potential role in care, the 2017 Society for Maternal-Fetal Medicine (SMFM) Annual Meeting dedicated a session to exploring early warning implementation across a wide range of hospital settings. This manuscript reports on key points from this session. While implementation experiences varied based on factors specific to individual sites, common themes relevant to all hospitals presenting were identified. Successful implementation of early warnings systems requires administrative and leadership support, dedication of resources, improved coordination between nurses, providers, and ancillary staff, optimization of information technology, effective education, evaluation of and change in hospital culture and practices, and support in provider decision-making. Evolving data on outcomes on early warning systems suggest that maternal risk may be reduced. To effectively reduce maternal, risk early warning systems that capture deterioration from a broad range of conditions may be required in addition to bundles tailored to specific conditions such as hemorrhage, thromboembolism, and hypertension.

Early Childhood Workforce Index, 2016

ERIC Educational Resources Information Center

Whitebook, Marcy; McLean, Caitlin; Austin, Lea J. E.

2016-01-01

The State of the Early Childhood Workforce (SECW) Initiative is a groundbreaking multi-year project to shine a steady spotlight on the nation's early childhood workforce. The SECW Initiative is designed to challenge entrenched ideas and policies that maintain an inequitable and inadequate status quo for early educators and for the children and…

Early Attrition among Suicidal Clients

ERIC Educational Resources Information Center

Surgenor, P. W. G.; Meehan, V.; Moore, A.

2016-01-01

The study aimed to identify the level of suicidal ideation in early attrition clients and their reasons for the early termination of their therapy. The cross-sectional design involved early attrition clients (C[subscript A]) who withdrew from therapy before their second session (n = 61), and continuing clients who (C[subscript C]) progressed…

Early Childhood Special Music Education

ERIC Educational Resources Information Center

Darrow, Alice-Ann

2011-01-01

The process of early intervention is a critical component of Early Childhood Special Music Education. Early intervention is the process of providing services, education, and support to young children who have disabilities or to children who are at-risk of developing needs that may affect their physical, cognitive, or emotional development. The…

Indicators of Access to Early Childhood Services in the Mississippi Delta. Rural Early Childhood Report No. 5

ERIC Educational Resources Information Center

Shores, Elizabeth F.; Barbaro, Erin; Barbaro, Michael C.; Flenner, Michelle; Bell, Lynn

2007-01-01

The Early Childhood Atlas facilitates spatial analysis in early childhood services research for the promotion of greater quality and accessibility of early care and education. The Atlas team collects and geocodes federal, state and nongovernmental datasets about early childhood services, integrating selected data elements into its online mapmaking…

Jean-Anthelme Brillat-Savarin's 1825 treatise on the mouth and ingestion.

PubMed

Chong, Gabriel Tse Feng

2012-12-01

This article quotes and discusses Jean-Anthelme Brillat-Savarin's musings on the mouth and ingestion as described in his book The Physiology of Taste. The book was first published in France in December 1825, and is still widely read as a key work in Gastronomy today. The mouth is intimately related to the acts of chewing, swallowing and eating and it would be interesting to report an early 19th century epicurean's views on the mouth. Passages from Brillat-Savarin's book describing the functions of the teeth and tongue and the acts of tasting, chewing, and swallowing are quoted in full. Anecdotes also include one on the horrifying punishment of having one's tongue removed and another illustrating the poor oral health found among Europeans of that era. His work offers a unique glimpse into how a 19th century gastronome viewed the oral cavity and its gastronomical functions. While some of his writings may appear archaic and antediluvian to the modern reader; others relating to, for example chewing and swallowing, are surprisingly accurate by contemporary standards. Nonetheless, the gastronomic savant seemed to know a lot right about modern stomatology! Copyright © 2012. Published by Elsevier B.V.

Nuclear power program and technology development in Korea

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cho, Byung-Oke

1994-12-31

KEPCO has successfully implemented the construction and operation of nuclear power plants since the early 1970s, and will continue to build safer and more efficient nuclear plants in the future in accordance with the nuclear power development plan previously established. KEPCO will also make every effort to enhance nuclear safety and obtain the public`s acceptance for nuclear power. We are, however, facing the same difficulties, as United States and other countries have, in strengthened regulatory requirements, public acceptance, radwaste disposal, and acquisition of new plant sites despite an active nuclear power program. Story of Ted Turner, CNN; {open_quotes}It ain`t asmore » easy as it looks.{close_quotes} Yes! It is difficult. But we will cope with these issues so that we can promote the nuclear power development and continue to supply a highly economical and clean energy to the world. In this regard, it is my sincere wish that each organization participating in the nuclear industry, especially Korea and United States strengthen their ties and help each other so that we together can successfully accomplish our goals.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Weldon Spring DOE grantee, St. Charles County, is seeking an early renewal on the Weldon Spring Grant order to match the grant`s reporting calendar with the County`s fiscal calendar which is January through December. Therefore, this renewal application will cover five months time instead of 12 months. This notified annual overview bridges a two month period that precedes the appointment and activation of the Weldon Spring Citizens Commission in February 1995. In the original grant application the County described its intent to select a volunteer Citizens Oversight Commission to monitor the cleanup activities at the DOE`s Weldon Spring Site.more » This commission would serve at the County`s watchdog group by monitoring Weldon Spring Site activities and provide on-going communication to the County`s residents through publications and forums. The first eight months of the project involved setting up the project office and working with a three member {open_quotes}Section Panel/Work Group{close_quotes} to select the Citizen`s Commission. These activities were coordinated by a Project Director hired by the County and funded from the initial grant funds.« less

Oswald Hall, PhD: Pioneer Canadian Sociologist; 1924–1976

PubMed Central

Brown, Douglas M.

2006-01-01

At ninety-eight (2006), Oswald Hall is Canada’s senior, distinguished sociologist. For several decades Dr. Hall’s colleagues have acknowledged his abiding “contributions to the growth of sociology in Canada and his loyalty to the profession.”1 The prime purpose of this paper is to document Dr. Hall’s legacy. It begins by briefly looking at Dr. Hall’s origins and early training. Then it investigates his graduate and postgraduate education and delves into his varied roles as a teacher, researcher, civil servant, and administrator, as well as his appointments to various advisory bodies, enquiries, boards and associations and concludes with a commentary on Oswald Hall’s accomplishments. Throughout the paper, Dr. Hall’s major publications are reviewed chronologically. This study does not include Hall’s twenty-seven year involvement with the chiropractic profession (1976 to 1998) because that era has been covered extensively in the December 2005 issue of the JCCA.2 Much of the article is based on testimony from colleagues and friends, as well as quotes from some of Hall’s unpublished writings and manuscripts. Unpublished Hall quotes are identified in the references by their titles and/or dates. PMID:17549188

Precursors of Adolescent Substance Use from Early Childhood and Early Adolescence: Testing a Developmental Cascade Model

PubMed Central

Sitnick, Stephanie; Shaw, Daniel S.; Hyde, Luke

2013-01-01

This study examined developmentally-salient risk and protective factors of adolescent substance use assessed during early childhood and early adolescence using a sample of 310 low-income boys. Child problem behavior and proximal family risk and protective factors (i.e., parenting, maternal depression) during early childhood, as well as child and family factors and peer deviant behavior during adolescence were explored as potential precursors to later substance use during adolescence using structural equation modeling. Results revealed that early childhood risk and protective factors (i.e., child externalizing problems, mothers’ depressive symptomatology, and nurturant parenting) were indirectly related to substance use at the age of 17 via risk and protective factors during early and middle adolescence (i.e., parental knowledge and externalizing problems). The implications of these findings for early prevention and intervention are discussed. PMID:24029248

Statistical Analysis of the Skaion Network Security Dataset

DTIC Science & Technology

2012-09-01

DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False, _ Semicolon:=False, Comma:=False, Space...Selection.TextToColumns Destination:=Range(“E1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False...True Columns(“F:F”).Select Selection.TextToColumns Destination:=Range(“F1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote

HullBUG Technology Development for Underwater Hull Cleaning

DTIC Science & Technology

2015-05-14

drawings would be vended out to approved vendors for quoting. Quotes would be obtained for different levels of production in order to better understand...the savings associated with buying more. Once a good pricing model was developed and quantity purchased determined, parts would be vended out and...detailed, dimensioned and tolerances added to enable quoting by commercial machine shops. A top assembly drawing was created that identified all

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tendera, P.

At present there are two NPPs equipped with PWR units in Czech Republic. The Dukovany NPP is about ten years in operation (four units 440 MW - WWER model 213) and Temelin NPP is under construction (two units 1000 MW-WWER model 320). Both NPPs were built to Soviet design and according to Soviet regulations and standards but most of equipment for primary circuits was supplied by home manufactures. The objective for the Czech LBB programme is to prove the LBB status of the primary piping systems of these NPPs and the LBB concept is a part of strategy to meetmore » western style safety standards. The reason for the Czech LBB project is a lack of some standard safety facilities, too. For both Dukovany and Temolin NPPs a full LBB analysis should be carried out. The application of LBB to the piping system should be also a cost effective means to avoid installations of pipe whip restraints and jet shields. The Czech regulatory body issued non-mandatory requirement {open_quotes}Leak Before Break{close_quotes} which is in compliance with national legal documents and which is based on the US NRC Regulatory Procedures and US standards (ASME, CODE, ANSI). The requirement has been published in the document {open_quotes}Safety of Nuclear Facilities{close_quotes} No. 1/1991 as {open_quotes}Requirements on the Content and Format of Safety Reports and their Supplements{close_quotes} and consists of two parts (1) procedure for obtaining proof of evidence {open_quotes}Leak Before Break{close_quotes} (2) leak detection systems for the pressurized reactor primary circuit. At present some changes concerning both parts of the above document will be introduced. The reasons for this modifications will be presented.« less

Common knowledge: Now you have it, now you don`t?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fagin, R.; Halpern, J.Y.; Moses, Y.

The notion of common knowledge, where everyone knows, everyone knows that everyone knows, etc., has proven to be fundamental in various disciplines, including Philosophy, Artificial Intelligence, Economics, and Psychology. This key notion was first studied by the philosopher David Lewis in the context of conventions. Lewis pointed out that in order for something to be a convention, it must in fact be common knowledge among the members of a group. (For example, the convention that green means {open_quotes}go{close_quotes} and red means {open_quotes}stop{close_quotes} is presumably common knowledge among the drivers in our society.) Common knowledge also arises in discourse understanding. Supposemore » Ann asks Bob {open_quotes}What did you think of the movie?{close_quotes} referring to a showing of Monkey Business they have just seen. Not only must Ann and Bob both know that {open_quotes}the movie{close_quotes} refers to Monkey Business, but Ann must know that Bob knows, Bob must know that Ann knows that Bob knows, and so on. In fact, by a closer analysis of this situation, it can be shown that there must be common knowledge of what movie is meant in order for Bob to answer the question appropriately. Finally, common knowledge also turns out to be a prerequisite for agreement and coordinated action in distributed systems. This is precisely what makes it such a crucial notion in the analysis of interacting groups of agents. On the other hand, in practical settings common knowledge is impossible to achieve. This puts us in a somewhat paradoxical situation, in that we claim both that common knowledge is a prerequisite for agreement and coordinated action and that it cannot be attained. We discuss two answers to this paradox: Modeling the world with a coarser granularity, and relaxing the requirements for coordination.« less

Contemporary Perspectives on Early Childhood Curriculum. Contemporary Perspectives in Early Childhood Education.

ERIC Educational Resources Information Center

Saracho, Olivia N. Ed.; Spodek, Bernard, Ed.

Noting that the curriculum in early childhood education is dramatically different from that at other levels of education, this volume seeks to clarify some of the issues related to early childhood curriculum development and its bases in both personal knowledge and knowledge from the different disciplines to achieve a "balanced curriculum."…

The Effect of Early Marriages and Early Childbearing on Women's Nutritional Status in India.

PubMed

Goli, Srinivas; Rammohan, Anu; Singh, Deepti

2015-08-01

The consequences of early childbearing on the growth and nutritional status of women in India has not been quantified in previous studies. Our study aimed to fill this gap by analysing the association between early marriage and early childbearing on nutritional status of Indian women, with a focus on Bihar and Andhra Pradesh, the two states accounting for the highest proportion of women marrying and giving first birth before 18 years of age. Our findings revealed that a substantial number of women were married before 18 years and thereby exposed to early pregnancy. Furthermore, a significantly higher proportion of women in the 'thin' category were married before 18 years, both in the Indian sample (33 %, p < 0.001) and in the selected states, Andhra Pradesh (31 %, p < 0.001) and Bihar (43 %, p < 0.001), compared to those women married at higher ages. Similarly, across all our samples women whose first birth was before age 18 years also had a significantly higher probability of being in the 'thin' category across all our samples. This pattern was also observed for associations between early childbirth and anemia levels. We conclude that the net effect of the early age at marriage and age at first birth on nutritional status is significant. Our results underline the need for preventing early marriages and the consequent high adolescent pregnancies in India, particularly in high prevalence states. This will help to improve nutritional status and health care utilisation among women, thereby, prevent maternal and child mortality and thus, achieve the MDGs 4-5.

Quantum Privacy Amplification and the Security of Quantum Cryptography over Noisy Channels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deutsch, D.; Ekert, A.; Jozsa, R.

1996-09-01

Existing quantum cryptographic schemes are not, as they stand, operable in the presence of noise on the quantum communication channel. Although they become operable if they are supplemented by classical privacy-amplification techniques, the resulting schemes are difficult to analyze and have not been proved secure. We introduce the concept of quantum privacy amplification and a cryptographic scheme incorporating it which is provably secure over a noisy channel. The scheme uses an {open_quote}{open_quote}entanglement purification{close_quote}{close_quote} procedure which, because it requires only a few quantum controlled-not and single-qubit operations, could be implemented using technology that is currently being developed. {copyright} {ital 1996 Themore » American Physical Society.}« less

High resolution x-ray CMT: Reconstruction methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, J.K.

This paper qualitatively discusses the primary characteristics of methods for reconstructing tomographic images from a set of projections. These reconstruction methods can be categorized as either {open_quotes}analytic{close_quotes} or {open_quotes}iterative{close_quotes} techniques. Analytic algorithms are derived from the formal inversion of equations describing the imaging process, while iterative algorithms incorporate a model of the imaging process and provide a mechanism to iteratively improve image estimates. Analytic reconstruction algorithms are typically computationally more efficient than iterative methods; however, analytic algorithms are available for a relatively limited set of imaging geometries and situations. Thus, the framework of iterative reconstruction methods is better suited formore » high accuracy, tomographic reconstruction codes.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oldham, D.W.

Commercial quantities of gas have been produced from shallow sandstone reservoirs of the Fort Union Formation (Paleocene) in the Powder River Basin of Wyoming. The two largest accumulations discovered to date, Oedekoven and Chan pools, were drilled on prospects which invoked differential compaction as a mechanism for gas entrapment and prospect delineation. Gas is believed to have accumulated in localized structural highs early in the burial history of lenticular sands. Structural relief is due to the compaction contrast between sand and stratigraphically-equivalent fine-grained sediments. A shallow Fort Union gas play was based on reports of shallow gas shows, the occurrencemore » of thick coals which could have served as sources for bacterial gas, and the presence of lenticular sandstones which may have promoted the development of compaction structures early in the burial process, to which bacterial gas migrated. Five geologic elements related to compactional trap development were used to rank prospects. Drilling of the Oedekoven prospect, which possessed all prospect elements, led to the discovery of the Oedekoven Fort Union gas pool at a depth of 340 ft (104 m). The uncemented, very fine grained, well-sorted {open_quotes}Canyon sand{close_quotes} pay has extremely high intergranular porosity. Low drilling and completion costs associated with shallow, high-permeability reservoirs, an abundance of subsurface control with which to delineate prospects, and existing gas-gathering systems make Fort Union sandstones attractive primary targets in shallow exploration efforts as well as secondary objectives in deeper drilling programs.« less

Late Cretaceous (Austin Group) volcanic deposits as a hydrocarbon trap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hutchinson, P.J.

1994-09-01

A Late Cretaceous submarine igneous extrusion occurs in the subsurface of southwestern Wilson County, Texas. The Coniacian-Santonian-aged (Austin Group) volcanic eruption discharged large volumes of magnetite-rich olivine nephelinite, that upon quenching, formed an extensive nontronitic clay layer. This clay deposit formed a trapping mechanism for hydrocarbons beneath the volcano; production from these features is normally attributed to the shoal-water carbonate facics developed on top of the volcano. The heat energy of the volcano may have thermally matured the calcareous sediments of the Austin Chalk contiguous with the volcano. The normally grayish-colored Austin Chalk in contact with the intrusive portion ofmore » the igneous material displays a greenish color suggesting thermal alteration. The overlying nontronite trapped the mobile hydrocarbons, and early emplacement may have preserved some of the original porosity and permeability of the Austin Chalk. Austin Chalk-aged volcanic deposits produce hydrocarbons from stratigraphic traps within the volcanic material, within the porous beachrock, and structurally within overlying sandstones. The intruded Austin Chalk also behaves as a reservoir because the original porosity and permeability is maintained through early emplacement of oil and the overlying volcanic clay prevents vertical migration. Marcefina Creek, discovered in 1980 from an {open_quotes}augen{close_quotes}-shaped seismic signature and an aerial magnetic survey, produces from the fractured chalk beneath the nontronitic clay layer. This field has produced over seven million bbl of oil from over 40 wells from fractured and porous rock beneath the volcano.« less

Switchgrass as a biofuels crop for the upper Southeast

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parrish, D.J.; Wolf, D.D.

1993-12-31

Switchgrass (Panicum virgatum) has been identified in DOE-sponsored studies as a widely adapted, productive herbaceous candidate for biofuels cropping. It is a perennial that has been planted using no-till procedures, and it appears to have positive effects on the soils in which it grows. We have been looking at this species as a potential fuelcrop (as well as a valuable forage) for several years. In this presentation, we note several {open_quotes}lessons learned{close_quotes} about switchgrass establishment and management as an energy crop. Data include results from recent plantings in the upper Southeast USA and from cutting management studies. Six varieties ofmore » switchgrass (Alamo, Cave-in-Rock, Kanlow, Shelter, and two breeder`s lines) varied markedly in the success of their no-till establishment at eight locations across the upper Southeast. Better weed control, which was achieved at later planting dates, seemed to be the key. Yields obtained in the establishment stands revealed that two harvests per season are more productive (by 2 to 3 Mg/ha) than one, but the date of first cutting is crucial. First cutting should be from late-June to mid-July. A two-cut system may not be economically advantageous, however. Another cutting-management study detected losses of standing biomass at the end of the growing season. As much as 15% of the above-ground biomass present in early-September was no longer harvestable in early-November. We think this loss results from translocation of dry matter to below-ground parts.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guariguata, U.G.

The European refining industry, along with its counterparts, is struggling with low profitability due to excess primary and conversion capacity, high operating costs and impending decisions of stringent environmental regulations that will require significant investments with hard to justify returns. This region was also faced in the early 1980s with excess capacity on the order of 4 MMb/d and satisfying the {open_quotes}at that point{close_quotes} demand by operating at very low utilization rates (60%). As was the case in the US, the rebalancing of the capacity led to the closure of some 51 refineries. Since the early 1990s, the increase inmore » demand growth has essentially balanced the capacity threshold and utilization rates are settled around the 90% range. During the last two decades, the major oil companies have reduced their presence in the European refining sector, giving some state oil companies and producing countries the opportunity to gain access to the consumer market through the purchase of refining capacity in various countries-specifically, Kuwait in Italy; Libya and Venezuela in Germany; and Norway in other areas of Scandinavia. Although the market share for this new cast of characters remains small (4%) relative to participation by the majors (35%), their involvement in the European refining business set the foundation whereby US independent refiners relinquished control over assets that could not be operated profitably as part of a previous vertically integrated structure, unless access to the crude was ensured. The passage of time still seems to render this model valid.« less

High normal blood pressure in early pregnancy also contribute to early onset preeclampsia and severe preeclampsia.

PubMed

He, Dian; Wu, Shaowen; Zhao, Haiping; Zheng, Zihe; Zhang, Weiyuan

2017-11-27

This study was to evaluate effects of high normal blood pressure (HNBP) in early pregnancy on total preeclampsia, early preeclampsia, and severe preeclampsia. We conducted a multicenter, national representative retrospective cohort study. HNBP was defined as systolic blood pressure between 130 and 140 mmHg or diastolic blood pressure between 85 and 90 mmHg. We used multivariable logistic regression to examine the associations of HNBP and the risks of above three types of preeclampsia. We included 58 054 women who were normotensive and nulliparous in early pregnancy. 4 809 (8.3%) fulfilled the definition of having HNBP, 16 682 (28.7%) were in normal blood pressure group, and 36 563 (63.0%) were in optimal blood pressure group. The incidence rates of total preeclampsia, early preeclampsia, and severe preeclampsia were 2.1% (1 217), 0.8% (491), and 1.4% (814), respectively. Compared to having optimal blood pressure, women with HNBP had significantly higher odds of total preeclampsia (odds ratio (OR) = 4.028, 95% confidence interval (CI) 3.377, 4.804), severe preeclampsia (OR = 3.542, 95% CI 2.851, 4.400), and early preeclampsia (OR = 8.163, 95% CI 6.219, 10.715). Our restricted cubic spline results supported the dose-response relationship between continuous blood pressure and the odds ratio of three types of preeclampsia. The fraction of early preeclampsia associated with prehypertension was 58.6%, which was higher than those of total preeclampsia (42.2%) or severe preeclampsia (40.5%). Women in early pregnancy with HNBP more likely develop total preeclampsia, early preeclampsia and severe preeclampsia, compared to those with optimal blood pressure. HNBP contribute more to early preeclampsia than severe preeclampsia. Our study provided robust epidemiological evidences for monitoring HNBP in early pregnancy to reduce the risks of preeclampsia.

The economics of stranded investment - a two-way street

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cearley, R.; McKinzie, L.

In the transition to deregulation, the risk, costs and benefits of utility assets are transferred from the customer to the investor, creating potential stranded benefits as well as stranded costs. Investors may be better or worse off depending on whether an asset`s cost is below or above market. Regulators can minimize unintended wealth transfers by compensating each potential loser in the transition. The amount of investment stranded - i.e., the portion of plant that is above market value - does seem to be a murky issue. This article sets a framework for evaluating stranded investment and traces the possible welfaremore » effects of different policies to address it. It defines {open_quote}stranded costs,{close_quote} {open_quote}stranded investment,{close_quote} and {open_quote}stranded benefits.{close_quote} It addresses their interrelationship, and shows that the redefinition of property rights during the transition to a competitive market is what leads to stranded investment. The elimination of the utility`s exclusive franchise - i.e., its obligation to serve and customers` obligation to pay - leads to the redefinition of those property rights as they pertain to the costs, benefits and risks associated with existing utility generation. Finally, the authors address the possible welfare implications from this transition.« less

A simplified financial model for automatic meter reading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ward, S.M.

1994-01-15

The financial model proposed here (which can be easily adapted for electric, gas, or water) combines aspects of [open quotes]life cycle,[close quotes] [open quotes]consumer value[close quotes] and [open quotes]revenue based[close quotes] approaches and addresses intangible benefits. A simple value tree of one-word descriptions clarifies the relationship between level of investment and level of value, visually relating increased value to increased cost. The model computes the numerical present values of capital costs, recurring costs, and revenue benefits over a 15-year period for the seven configurations: manual reading of existing or replacement standard meters (MMR), manual reading using electronic, hand-held retrievers (EMR),more » remote reading of inaccessible meters via hard-wired receptacles (RMR), remote reading of meters adapted with pulse generators (RMR-P), remote reading of meters adapted with absolute dial encoders (RMR-E), offsite reading over a few hundred feet with mobile radio (OMR), and fully automatic reading using telephone or an equivalent network (AMR). In the model, of course, the costs of installing the configurations are clearly listed under each column. The model requires only four annualized inputs and seven fixed-cost inputs that are rather easy to obtain.« less

SRS stainless steel beneficial reuse program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boettinger, W.L.

1997-02-01

The US Department of Energy`s (DOE) Savannah River Site (SRS) has thousands of tons of stainless steel radioactive scrap metal (RSNI). Much of the metal is volumetrically contaminated. There is no {open_quotes}de minimis{close_quotes} free release level for volumetric material, and therefore no way to recycle the metal into the normal commercial market. If declared waste, the metal would qualify as low level radioactive waste (LLW) and ultimately be dispositioned through shallow land buried at a cost of millions of dollars. The metal however could be recycled in a {open_quotes}controlled release{close_quote} manner, in the form of containers to hold other typesmore » of radioactive waste. This form of recycle is generally referred to as {open_quotes}Beneficial Reuse{close_quotes}. Beneficial reuse reduces the amount of disposal space needed and reduces the need for virgin containers which would themselves become contaminated. Stainless steel is particularly suited for long term storage because of its resistance to corrosion. To assess the practicality of stainless steel RSM recycle the SRS Benficial Reuse Program began a demonstration in 1994, funded by the DOE Office of Science and Technology. This paper discusses the experiences gained in this program.« less

Gist: A scientific graphics package for Python

DOE Office of Scientific and Technical Information (OSTI.GOV)

Busby, L.E.

1996-05-08

{open_quotes}Gist{close_quotes} is a scientific graphics library written by David H. Munro of Lawrence Livermore National Laboratory (LLNL). It features support for three common graphics output devices: X Windows, (Color) PostScript, and ANSI/ISO Standard Computer Graphics Metafiles (CGM). The library is small (written directly to Xlib), portable, efficient, and full-featured. It produces X versus Y plots with {open_quotes}good{close_quotes} tick marks and tick labels, 2-dimensional quadrilateral mesh plots with contours, vector fields, or pseudo color maps on such meshes, with 3-dimensional plots on the way. The Python Gist module utilizes the new {open_quotes}Numeric{close_quotes} module due to J. Hugunin and others. It ismore » therefore fast and able to handle large datasets. The Gist module includes an X Windows event dispatcher which can be dynamically added (e.g., via importing a dynamically loaded module) to the Python interpreter after a simple two-line modification to the Python core. This makes fast mouse-controlled zoom, pan, and other graphic operations available to the researcher while maintaining the usual Python command-line interface. Munro`s Gist library is already freely available. The Python Gist module is currently under review and is also expected to qualify for unlimited release.« less

Model curriculum outline for Alternatively Fueled Vehicle (AFV) automotive technician training in light and medium duty CNG and LPG

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This model curriculum outline was developed using a turbo-DACUM (Developing a Curriculum) process which utilizes practicing experts to undertake a comprehensive job and task analysis. The job and task analysis serves to establish current baseline data accurately and to improve both the process and the product of the job through constant and continuous improvement of training. The DACUM process is based on the following assumptions: (1) Expert workers are the best source for task analysis. (2) Any occupation can be described effectively in terms of tasks. (3) All tasks imply knowledge, skills, and attitudes/values. A DACUM panel, comprised of sixmore » experienced and knowledgeable technicians who are presently working in the field, was given an orientation to the DACUM process. The panel then identified, verified, and sequenced all the necessary job duty areas and tasks. The broad duty categories were rated according to relative importance and assigned percentage ratings in priority order. The panel then rated every task for each of the duties on a scale of 1 to 3. A rating of 3 indicates an {open_quotes}essential{close_quotes} task, a rating of 2 indicates an {open_quotes}important{close_quotes} task, and a rating of 1 indicates a {open_quotes}desirable{close_quotes} task.« less

Nuclear power grows in China`s energy mix

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Xavier

1996-07-01

China`s rapid economic growth in the past two decades has caused the nations`s demand for electricity to exceed its capacity. AS of 1992, with power shortages as high as 25 percent, {open_quotes}power plant operators were often forced to resort to rolling brownouts to avoid complete system breakdowns,{close_quotes} says Xavier Chen, an assistant professor with the Asian Institute of Technology`s Energy Program in Bangkok, Thailand. To keep pace with China`s economic development, Chen estimates that {open_quotes}China must increase its electricity capacity 6 to 8 percent a year each year into the foreseeable future.{close_quotes} For now, coal is transported to power plantsmore » in the rapidly developing eastern coastal provinces at great expense. Chen also notes that the environmental disadvantages of coal make it a less desirable source of energy than nuclear. Development of nuclear energy is likely to go forward for another reason: In China, there is much less opposition to nuclear power plants than in other developing nations. {open_quotes}Nuclear energy likely will plan an important role in China`s future energy mix and help close the gap between electricity production and demand,{close_quotes} Chen says.« less

Stochastic dynamics in a two-dimensional oscillator near a saddle-node bifurcation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Inchiosa, M. E.; In, V.; Bulsara, A. R.

We study the oscillator equations describing a particular class of nonlinear amplifier, exemplified in this work by a two-junction superconducting quantum interference device. This class of dynamic system is described by a potential energy function that can admit minima (corresponding to stable solutions of the dynamic equations), or {open_quotes}running states{close_quotes} wherein the system is biased so that the potential minima disappear and the solutions display spontaneous oscillations. Just beyond the onset of the spontaneous oscillations, the system is known to show significantly enhanced sensitivity to very weak magnetic signals. The global phase space structure allows us to apply a centermore » manifold technique to approximate analytically the oscillatory behavior just past the (saddle-node) bifurcation and compute the oscillation period, which obeys standard scaling laws. In this regime, the dynamics can be represented by an {open_quotes}integrate-fire{close_quotes} model drawn from the computational neuroscience repertoire; in fact, we obtain an {open_quotes}interspike interval{close_quotes} probability density function and an associated power spectral density (computed via Renewal theory) that agree very well with the results obtained via numerical simulations. Notably, driving the system with one or more time sinusoids produces a noise-lowering injection locking effect and/or heterodyning.« less

Rethinking Early Childhood Education

ERIC Educational Resources Information Center

Pelo, Ann, Ed.

2008-01-01

"Rethinking Early Childhood Education" is alive with the conviction that teaching young children involves values and vision. This anthology collects inspiring stories about social justice teaching with young children. Included here is outstanding writing from childcare teachers, early-grade public school teachers, scholars, and parents.…

Early Head Start: Research Findings. Early Childhood Highlights. Volume 1, Issue 2

ERIC Educational Resources Information Center

Child Trends, 2010

2010-01-01

Early Head Start is a federally funded community-based program for low-income families with infants and toddlers and for low-income pregnant women. Created in 1995, Early Head Start strives to promote healthy prenatal outcomes for pregnant women, to enhance the development of children ages birth to three, and to promote healthy family functioning.…

Early Intervention Services for Early-Phase Psychosis - Centre for integrative psychiatry in Psychiatric Hospital "Sveti Ivan", Croatia.

PubMed

Matić, Katarina; Gereš, Natko; Gerlach, Josefina; Prskalo-Čule, Diana; Zadravec Vrbanc, Tihana; Lovretić, Vanja; Librenjak, Dina; Vuk Pisk, Sandra; Ivezić, Ena; Šimunović Filipčić, Ivona; Jeleč, Vjekoslav; Filipčić, Igor

2018-06-01

There is a growing body of evidence suggesting that early and effective management in the critical early years of schizophrenia can improve long-term outcomes. The objective of this study was to evaluate time to relapse of the patients with early-phase psychosis treated in the Centre for integrative psychiatry (CIP). We performed a retrospective cohort study on the sample of 373 early-phase psychosis patients admitted to Psychiatric Hospital "Sveti Ivan", Zagreb Croatia: from January 1, 2015 to December 31, 2017. The primary outcome was time to relapse. Patients who were admitted to group psychotherapeutic program after the end of acute treatment had 70% lower hazard for relapse (HR=0.30; 95% CI 0.16-0.58). Patients who were included first in the psychotherapeutic program and then treated and controlled in the daily hospital had 74% lower hazard for relapse (HR=0.26; 95% CI 0.10-0.67). In early-phase psychosis, integrative early intervention service has relevant beneficial effects compare to treatment as usual. These results justified the implementation of multimodal early intervention services in treatment of patients with early-phase psychosis.

Characterization of the patterns of polymorphism in a [open quotes]cryptic repeat[close quotes] reveals a novel type of hypervariable sequence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobson, D.P.; Schmeling, P.; Sommer, S.S.

Alternating purine and pyrimidine repeats (RY(i)) are an abundant source of polymorphism. The subset with long tandem repeats of GT or AC (GT(i)) have been studied extensively, but cryptic RY(i) (i.e., no single tandem repeat predominates) have received little attention. The factor IX gene has a polymorphic cryptic RY(i) of 142-216 bp. Previously, there were four known polymorphic alleles, of the form AB, A[sub 2]B, A[sub 2]B[sub 2], and A[sub 3]B[sub 2], where A = (GT)(AC)[sub 3](AT)[sub 3](GT)(AT)[sub 4] and B = A with an additional 3' AT dinucleotide. To further characterize this locus, the authors examined more than 1,700more » additional human chromosomes and determined the sequences of the homologous sites in orangutans and chimpanzees. The novel alleles found in humans expand the repertoire of A/B alleles to A[sub 0-4]B[sub 1] and A[sub 1-3]B[sub 2]. The A[sub n]B[sub 2] series are abundant in Caucasians but are absent in blacks and Asians. Conversely, the A[sub 0]B[sub 1] allele is common in blacks but is not found in more than 1,700 Caucasian chromosomes. The data are compatible with a model in which recombination is more frequent than polymerase slippage at this locus. In orangutans, the RY(i) is present, but the sequence is markedly different. An A/B-type of pattern was discerned in which B differs from A by an additional six (AT) dinucleotides at the 3' end. In chimpanzees, the size of the RY(i) locus was greatly expanded, and the sequence showed a novel pattern of hypervariability in which there are many tandem repeats of the form (GT)[sub n](AC)[sub 0](AT)[sub p](GT)[sub q](AT)[sub s], where n, o, p, q, and s are different integers. The sequences of the factor IX intron 1 cryptic RY(i) in three primates provide perspective on the range of possible patterns of polymorphism. Analysis of the patterns suggests how the RY(i) can be conserved during evolution, while the precise sequence varies. 25 refs., 5 figs., 3 tabs.« less

Nature of plant stimulators in the production of Acetobacter xylinum ({open_quotes}Tea fungas{close_quotes}) biofilm used in skin therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fontana, J.D.; Franco, V.C.; Lyra, I.N.

1991-12-31

Caffeine and related xanthines were identified as potent stimulators for the bacterial cellulose production in A. xylinum. These compounds are present in several plants whose infusions are useful as culture-medium supplements for this acetobacterium. The proposed target for these native purine-like inhibitory substances is the novel diguanyl nucleotide phosphodiesterase(s) that participates in the bacterial cellulogenic complex.

HullBUG Technology Development for Underwater Hull Cleaning

DTIC Science & Technology

2013-08-23

drawings of the Grooming Tool would be generated. These drawings would be vended out to approved vendors for quoting. Quotes would be obtained for...quantity purchased determined, parts would be vended out and manufactured. These parts would then be assembled at SRC. A test program would then follow...tolerances added to enable quoting by commercial machine shops. A top assembly drawing was created that identified all machined parts as well as all

The Psychologist Said Quickly, “Dialogue Descriptions Modulate Reading Speed!”

PubMed Central

Stites, Mallory C.; Luke, Steven G.; Christianson, Kiel

2012-01-01

The current study investigates whether the semantic content of a dialogue description can affect reading times on an embedded quote to determine if the speed at which a character is described as saying a quote influences how quickly it is read. Yao and Scheepers (2011) previously found that readers were faster to read direct quotes when the preceding context implied that the talker generally spoke quickly, an effect attributed to perceptual simulation of talker speed. The current study manipulated the speed of a physical action performed by the speaker independently from character talking rate to determine if these sources have separable effects on perceptual simulation of a direct quote. Results showed that readers spent less time reading direct quotes described as being said quickly compared to slowly (e.g., John walked/bolted into the room and said energetically/nonchalantly, “I finally found my car keys”), an effect that was not present when a nearly identical phrase was presented as an indirect quote (e.g., John…said energetically that he finally found his car keys). The speed of the character’s movement did not affect direct quote reading times. Furthermore, fast adverbs were themselves read significantly faster than slow adverbs, an effect we attribute to implicit effects on the eye movement program stemming from automatically activated semantic features of the adverbs. Our findings add to the literature on perceptual simulation by showing that these effects can be instantiated with only a single adverb, and are strong enough to override effects of global sentence speed. PMID:22927027

The Influence of the Early Retirement Process on Satisfaction with Early Retirement and Psychological Well-Being

ERIC Educational Resources Information Center

Potocnik, Kristina; Tordera, Nuria; Peiro, Jose Maria

2010-01-01

The present study explores the influence of the early retirement process on adjustment to early retirement, taking into account the roles of individual characteristics and social context in this process. We proposed a systematic model integrating perceived ability to continue working, organizational pressures toward early retirement and group…

Early osteoarthritis of the knee.

PubMed

Madry, Henning; Kon, Elizaveta; Condello, Vincenzo; Peretti, Giuseppe M; Steinwachs, Matthias; Seil, Romain; Berruto, Massimo; Engebretsen, Lars; Filardo, Giuseppe; Angele, Peter

2016-06-01

There is an increasing awareness on the importance in identifying early phases of the degenerative processes in knee osteoarthritis (OA), the crucial period of the disease when there might still be the possibility to initiate treatments preventing its progression. Early OA may show a diffuse and ill-defined involvement, but also originate in the cartilage surrounding a focal lesion, thus necessitating a separate assessment of these two entities. Early OA can be considered to include a maximal involvement of 50 % of the cartilage thickness based on the macroscopic ICRS classification, reflecting an OARSI grade 4. The purpose of this paper was to provide an updated review of the current status of the diagnosis and definition of early knee OA, including the clinical, radiographical, histological, MRI, and arthroscopic definitions and biomarkers. Based on current evidence, practical classification criteria are presented. As new insights and technologies become available, they will further evolve to better define and treat early knee OA.

Growth hormone and early treatment.

PubMed

Antoniazzi, F; Cavarzere, P; Gaudino, R

2015-06-01

Growth hormone (GH) treatment is approved by the US Food and Drug Administration (FDA) not only for GH deficiency (GHD) but also for other childhood growth disorders with growth failure and/or short stature. GHD is the most frequent endocrine disorder presenting with short stature in childhood. During neonatal period, metabolic effects due to congenital GHD require a prompt replacement therapy to avoid possible life-threatening complications. In childhood and adolescence, growth impairment is the most evident effect of GHD and early treatment has the aim of restore normal growth and to reach normal adult height. We reassume in this review the conditions causing GHD and the diagnostic challenge to reach an early diagnosis, and an early treatment, necessary to obtain the best results. Finally, we summarize results obtained in clinical studies about pediatric patients with GHD treated at an early age, in which a marked early catch-up growth and a normalization of adult height were obtained.

Space educators' handbook

NASA Technical Reports Server (NTRS)

Woodfill, Jerry

1992-01-01

The Space Educators' Handbook is a collection of space exploration information available on Hypercard as a space education reference book. Ranging from early dreams of space ships to current manned missions, the more than four thousand cards include entries of statistics, historical facts and anecdotes, technical articles, accounts of NASA missions from Mercury through the space shuttle, biographical information on women and men who have contributed to space exploration, scientific facts, and various other space-related data. The means of presenting the data range from cartoons and drawings to lists and narratives, some briefly quoted and some reproduced in full.

Preventive child health care findings on early childhood predict peer-group social status in early adolescence.

PubMed

Jaspers, Merlijne; de Winter, Andrea F; Veenstra, René; Ormel, Johan; Verhulst, Frank C; Reijneveld, Sijmen A

2012-12-01

A disputed social status among peers puts children and adolescents at risk for developing a wide range of problems, such as being bullied. However, there is a lack of knowledge about which early predictors could be used to identify (young) adolescents at risk for a disputed social status. The aim of this study was to assess whether preventive child health care (PCH) findings on early childhood predict neglected and rejected status in early adolescence in a large longitudinal community-based sample. Data came from 898 participants who participated in TRAILS, a longitudinal study. Information on early childhood factors was extracted from the charts of routine PCH visits registered between infancy and age of 4 years. To assess social status, peer nominations were used at age of 10-12 years. Multinomial logistic regression showed that children who had a low birth weight, motor problems, and sleep problems; children of parents with a low educational level (odds ratios [ORs] between 1.71 and 2.90); and those with fewer attention hyperactivity problems (ORs = .43) were more likely to have a neglected status in early adolescence. Boys, children of parents with a low educational level, and children with early externalizing problems were more likely to have a rejected status in early adolescence (ORs between 1.69 and 2.56). PCH findings on early childhood-on motor and social development-are predictive of a neglected and a rejected status in early adolescence. PCH is a good setting to monitor risk factors that predict the social status of young adolescents. Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Early Intervention in Bipolar Disorder.

PubMed

Vieta, Eduard; Salagre, Estela; Grande, Iria; Carvalho, André F; Fernandes, Brisa S; Berk, Michael; Birmaher, Boris; Tohen, Mauricio; Suppes, Trisha

2018-05-01

Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and usually has its onset during youth. Its chronic course is associated with high rates of morbidity and mortality, making bipolar disorder one of the main causes of disability among young and working-age people. The implementation of early intervention strategies may help to change the outcome of the illness and avert potentially irreversible harm to patients with bipolar disorder, as early phases may be more responsive to treatment and may need less aggressive therapies. Early intervention in bipolar disorder is gaining momentum. Current evidence emerging from longitudinal studies indicates that parental early-onset bipolar disorder is the most consistent risk factor for bipolar disorder. Longitudinal studies also indicate that a full-blown manic episode is often preceded by a variety of prodromal symptoms, particularly subsyndromal manic symptoms, therefore supporting the existence of an at-risk state in bipolar disorder that could be targeted through early intervention. There are also identifiable risk factors that influence the course of bipolar disorder, some of them potentially modifiable. Valid biomarkers or diagnosis tools to help clinicians identify individuals at high risk of conversion to bipolar disorder are still lacking, although there are some promising early results. Pending more solid evidence on the best treatment strategy in early phases of bipolar disorder, physicians should carefully weigh the risks and benefits of each intervention. Further studies will provide the evidence needed to finish shaping the concept of early intervention. AJP AT 175 Remembering Our Past As We Envision Our Future April 1925: Interpretations of Manic-Depressive Phases Earl Bond and G.E. Partridge reviewed a number of patients with manic-depressive illness in search of a unifying endo-psychic conflict. They concluded that understanding either phase of illness was "elusive" and

Waterford Early Reading Program.

ERIC Educational Resources Information Center

Education Commission of the States, Denver, CO.

This paper provides an overview of the Waterford Early Reading Program (WERP), which is designed to shift teaching and learning away from remediation and failure to prevention, early achievement, and sustained growth for every student. WERP includes three levels of instruction: emergent, beginning, and fluent readers. It targets pre-K through…

Children's early helping in action: Piagetian developmental theory and early prosocial behavior.

PubMed

Hammond, Stuart I

2014-01-01

After a brief overview of recent research on early helping, outlining some central problems, and issues, this paper examines children's early helping through the lens of Piagetian moral and developmental theory, drawing on Piaget's "Moral Judgment of the Child" (Piaget, 1932/1997), "Play, Dreams, and Imitation in Childhood" (Piaget, 1945/1951), and the "Grasp of Consciousness" (Piaget, 1976). Piaget refers to a level of moral development in action that precedes heteronomous and autonomous moral reasoning. This action level allows children to begin to interact with people and objects. In his later work, Piaget explores the gradual construction of understanding from this activity level. Taken together, these elements of Piagetian theory provide a promising conceptual framework for understanding the development of early helping.

Early Childhood Educators' Perceived and Actual Metalinguistic Knowledge, Beliefs and Enacted Practice about Teaching Early Reading

ERIC Educational Resources Information Center

Hammond, Lorraine

2015-01-01

Results of influential reports on early literacy have drawn attention to the need for early childhood educators to take up a more explicit, teacher-directed approach to beginning reading. Positive classroom results however are in part dependent upon teacher knowledge and this study investigated the relationship between early childhood educators'…

Early presentation of primary glioblastoma.

PubMed

Faguer, R; Tanguy, J-Y; Rousseau, A; Clavreul, A; Menei, P

2014-08-01

Clinical and neuroimaging findings of glioblastomas (GBM) at an early stage have rarely been described and those tumors are most probably under-diagnosed. Furthermore, their genetic alterations, to our knowledge, have never been previously reported. We report the clinical as well as neuroimaging findings of four early cases of patients with GBM. In our series, early stage GBM occurred at a mean age of 57 years. All patients had seizures as their first symptom. In all early stages, MRI showed a hyperintense signal on T2-weighted sequences and an enhancement on GdE-T1WI sequences. A hyperintense signal on diffusion sequences with a low ADC value was also found. These early observed occurrences of GBM developed rapidly and presented the MRI characteristics of classic GBM within a few weeks. The GBM size was multiplied by 32 in one month. Immunohistochemical analysis indicated the de novo nature of these tumors, i.e. absence of mutant IDH1 R132H protein expression, which is a diagnostic marker of low-grade diffuse glioma and secondary GBM. A better knowledge of early GBM presentation would allow a more suitable management of the patients and may improve their prognosis. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Sharing Books with Babies: Promoting Early Literacy in Early Care and Education. [Videotape].

ERIC Educational Resources Information Center

Boston Medical Center, MA. Doc4Kids Project.

Suggesting that very young children spend every waking minute getting ready for kindergarten, this videotape for caregivers and early childhood teachers shows how to support early literacy skill development by sharing stories, relationships, and books with infants, toddlers, and preschoolers in care and education settings. The 25-minute videotape…

Emotional Self-Regulation, Peer Rejection, and Antisocial Behavior: Developmental Associations from Early Childhood to Early Adolescence

ERIC Educational Resources Information Center

Trentacosta, Christopher J.; Shaw, Daniel S.

2009-01-01

This study examined relations among emotional self-regulation, peer rejection, and antisocial behavior in a sample of 122 boys from low-income families who participated in a summer camp and were followed longitudinally from early childhood to early adolescence. Emotional self-regulation strategies were coded in early childhood from a waiting task,…

Theoretical motivation for gravitation experiments on ultra-low energy antiprotons and antihydrogen

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nieto, M.M.

1995-12-31

It is known that the generally accepted theories of gravity and quantum mechanics are fundamentally incompatible. Thus, when one tries to combine these theories, one must beware of physical pitfalls. Modern theories of quantum gravity are trying to overcome these problems. Any ideas must confront the present agreement with general relativity, but yet be free to wonder about not understood phenomena, such as the dark matter problem. This all has led some {open_quotes}intrepid{close_quotes} theorists to consider a new gravitational regime, that of antimatter. Even more {open_quotes}daring{close_quotes} experimentalists are attempting, or considering attempting, the measurement of the gravitational force on antimatter,more » including low-energy antiprotons and, perhaps most enticing, antihydrogen.« less

The Value of Transparency in Distributed Solar PV Markets

DOE Office of Scientific and Technical Information (OSTI.GOV)

OShaughnessy, Eric J.; Margolis, Robert M.

Distributed solar photovoltaic (PV) markets are relatively non-transparent: PV price and product information is not readily available, searching for this information is costly (in terms of time and effort), and customers are mostly unfamiliar with the new technology. Quote aggregation, where third-party companies collect PV quotes on behalf of customers, may be one way to increase PV market transparency. In this paper, quote aggregation data are analyzed to study the value of transparency for distributed solar PV markets. The results suggest that easier access to more quotes results in lower prices. We find that installers tend to offer lower pricesmore » in more competitive market environments. We supplement the empirical analysis with key findings from interviews of residential PV installers.« less

US PWR steam generator management: An overview

DOE Office of Scientific and Technical Information (OSTI.GOV)

Welty, C.S. Jr.

1997-02-01

This paper provides an overview on the status of steam generator management activities in US PWRs, and includes: (1) an overview of the impact of steam generator problems; (2) a brief discussion of historical damage trends and the current damage mechanism of most concern; (3) a discussion of the elements of {open_quotes}steam generator management{close_quotes}; and (4) a description of the approach being followed to implement a degradation-specific protocol for tubing inspection and repair. This paper was prepared in conjunction with another paper presented during the Plenary Session of this Conference, {open_quotes}Steam Generator Degradation: Current Mitigation Strategies for Controlling Corrosion{close_quotes}, andmore » is provided as a supplement to that material.« less

Fullerene discoverers win nobel prize

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rotman, D.

1996-10-16

Two Rice University (Houston) chemists, Robert F. Curl and Richard E. Smalley, and a scientist at the University of Sussex (Brighton, U.K.), Harold W. Kroto, have won the 1996 Nobel Prize in Chemistry for the joint discovery of buckminsterfullerenes - soccer ball-shaped carbon molecules. The novel form of carbon, which was initially synthesized by the scientists in 1985 as C{sub 60} and C{sub 70} has led to the development of {open_quotes}an entirely new branch of chemistry... with consequences in such diverse areas as astrochemistry, superconductivity, and material chemistry/physics,{close_quotes} according to the Swedish Academy of Sciences (Stockholm). For chemists, the structuremore » is {open_quotes}uniquely beautiful and satisfying,{close_quotes} the academy says.« less

The At Risk Child: Early Identification, Intervention, and Evaluation of Early Childhood Strategies.

ERIC Educational Resources Information Center

Lennon, Joan M.

A review of literature was conducted in order to: (1) determine whether factors placing the young child at risk for school failure can be identified; (2) determine whether early family interventions and early childhood programs are effective; and (3) identify policy implications. Findings are summarized, and recommendations are offered. Research…

Taiwanese Early Childhood Educators' Professional Development

ERIC Educational Resources Information Center

Hsu, Ching-Yun

2008-01-01

This study was designed based on a qualitative paradigm to explore the professional development of Taiwanese early childhood educators. The method of phenomenology was employed. The main research question addressed was "How do early childhood educators construe their professional development experience?" Seven Taiwanese early childhood…

Resilience in mathematics after early brain injury: The roles of parental input and early plasticity.

PubMed

Glenn, Dana E; Demir-Lira, Özlem Ece; Gibson, Dominic J; Congdon, Eliza L; Levine, Susan C

2018-04-01

Children with early focal unilateral brain injury show remarkable plasticity in language development. However, little is known about how early brain injury influences mathematical learning. Here, we examine early number understanding, comparing cardinal number knowledge of typically developing children (TD) and children with pre- and perinatal lesions (BI) between 42 and 50 months of age. We also examine how this knowledge relates to the number words children hear from their primary caregivers early in life. We find that children with BI, are, on average, slightly behind TD children in both cardinal number knowledge and later mathematical performance, and show slightly slower learning rates than TD children in cardinal number knowledge during the preschool years. We also find that parents' "number talk" to their toddlers predicts later mathematical ability for both TD children and children with BI. These findings suggest a relatively optimistic story in which neural plasticity is at play in children's mathematical development following early brain injury. Further, the effects of early number input suggest that intervening to enrich the number talk that children with BI hear during the preschool years could narrow the math achievement gap. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

75 FR 63232 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-14

... (``SLPs''), the Exchange is modifying language referencing the SLP quoting requirement to reflect a recent... modifying language referencing the SLP quoting requirement to reflect a recent rule filing that changed the...

23 CFR 710.501 - Early acquisition.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Early acquisition. 710.501 Section 710.501 Highways... REAL ESTATE Property Acquisition Alternatives § 710.501 Early acquisition. (a) Real property... so based on program or project considerations. The State may undertake early acquisition for corridor...

23 CFR 710.501 - Early acquisition.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Early acquisition. 710.501 Section 710.501 Highways... REAL ESTATE Property Acquisition Alternatives § 710.501 Early acquisition. (a) Real property... so based on program or project considerations. The State may undertake early acquisition for corridor...

Treatment of early Parkinson's disease.

PubMed

Pahwa, Rajesh; Lyons, Kelly E

2014-08-01

This review summarizes currently available treatment options and treatment strategies, investigational treatments, and the importance of exercise for early Parkinson's disease. The available treatment options for early Parkinson's disease have changed little in the past decade and include carbidopa/levodopa, dopamine agonists, and monoamine oxidase type B (MAO-B) inhibitors. However, we discuss changes in treatment strategies, including dosing and the use of combination therapy used in an attempt to reduce or delay the appearance of motor complications and other adverse events. We will also review several investigational treatments that have shown promise for the treatment of early Parkinson's disease, including a new extended release formulation of carbidopa/levodopa (IPX066), safinamide which inhibits MAO-B, dopamine uptake and glutamate and pardoprunox which is a 5HT-1A agonist and a partial dopamine agonist. Finally, we discuss recent studies focusing on exercise as an important component in the management of early Parkinson's disease. Advances in the management of early Parkinson's disease include evolving treatment strategies, new investigational treatments, and earlier implementation of various forms of exercise.

Early Life Exposures and Cancer

Cancer.gov

Early-life events and exposures have important consequences for cancer development later in life, however, epidemiological studies of early-life factors and cancer development later in life have had significant methodological challenges.

48 CFR 8.405-2 - Ordering procedures for services requiring a statement of work.

Code of Federal Regulations, 2011 CFR

2011-10-01

... quote; or (B) Provide the RFQ to as many schedule contractors as practicable, consistent with market research appropriate to the circumstances, to reasonably ensure that quotes will be received from at least...

Natural course of early COPD.

PubMed

Rhee, Chin Kook; Kim, Kyungjoo; Yoon, Hyoung Kyu; Kim, Jee-Ae; Kim, Sang Hyun; Lee, Sang Haak; Park, Yong Bum; Jung, Ki-Suck; Yoo, Kwang Ha; Hwang, Yong Il

2017-01-01

Few studies have examined the natural course of early COPD. The aim of this study was to observe the natural course of early COPD patients. We also aimed to analyze medical utilization and costs for early COPD during a 6-year period. Patients with early COPD were selected from Korean National Health and Nutrition Examination Survey (KNHANES) data. We linked the KNHANES data of patients with early COPD to National Health Insurance data. A total of 2,397 patients were enrolled between 2007 and 2012. The mean forced expiratory volume in 1 second (FEV 1 ) was 78.6%, and the EuroQol five dimensions questionnaire (EQ-5D) index value was 0.9. In total, 110 patients utilized health care for COPD in 2007, and this number increased to 179 in 2012. The total mean number of days used per person increased from 4.9 in 2007 to 7.8 in 2012. The total medical cost per person also increased from 248.8 US dollar (USD) in 2007 to 780.6 USD in 2013. A multiple linear regression revealed that age, lower body mass index, lower FEV 1 (%), and lower EQ-5D score were significantly associated with medical costs. Even in early COPD patients, some of them eventually progressed and utilized health care for COPD.

28 CFR 2.43 - Early termination.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Early termination. 2.43 Section 2.43..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.43 Early... shall also conduct a status review whenever the supervision officer recommends early termination of the...

28 CFR 2.43 - Early termination.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Early termination. 2.43 Section 2.43..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.43 Early... shall also conduct a status review whenever the supervision officer recommends early termination of the...

28 CFR 2.43 - Early termination.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Early termination. 2.43 Section 2.43..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.43 Early... shall also conduct a status review whenever the supervision officer recommends early termination of the...

28 CFR 2.43 - Early termination.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Early termination. 2.43 Section 2.43..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.43 Early... shall also conduct a status review whenever the supervision officer recommends early termination of the...

28 CFR 2.43 - Early termination.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Early termination. 2.43 Section 2.43..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.43 Early... shall also conduct a status review whenever the supervision officer recommends early termination of the...

Equity Starts Early: Addressing Racial Inequities in Child Care and Early Education Policy

ERIC Educational Resources Information Center

Johnson-Staub, Christine

2017-01-01

Child care and early education policies are shaped by a history of systemic and structural racism. This has created major racial disparities in children's access to quality child care that meets their cultural and linguistic needs and enables their parents to work. Early care and education workers are overwhelmingly in low-quality jobs with…

NASA Early Career Fellowship Program

NASA Astrophysics Data System (ADS)

Smith, H. D.

2012-12-01

The Early Career Fellowship program was established in 2005 to facilitate the integration of outstanding early career planetary science researchers into established research funding programs by providing tools and experience useful to maintain a successful research program. Executing a successful research program requires a few key elements such as: successful proposal writing; adequate (paid) research time; management of a laboratory; collaboration and networking; frequent and high-quality publications; and adequate start-up equipment funds. These elements may be particularly critical for early career researchers searching for a tenure- track or equivalent position. The Early Career Fellowship program recognizes the importance of these skills and provides extra funding and resources to begin a successful research program. For consideration into The Early Career Fellowship program, the candidate needs to be the P. I. or Science P.I. of a funded research proposal from one of the participating R&A program areas, be within 7 years of earning a PhD, hold a non-tenure track position, and indicate the early career candidacy when submitting the research proposal. If the research proposal is funded and the discipline scientist nominates the candidate as an early career fellow, the candidate is then considered a Fellow and eligible to propose for Step 2. Upon obtaining a tenure-track equivalent position the Fellow submits a Step 2 proposal for up to one hundred thousand dollars in start-up funds. Start-up funds may be used for salary; undergraduate and/or graduate research assistants; supplies and instrument upgrades; travel to conferences, meetings, and advisory groups; time and travel for learning new skills; publication page charges; books and journal subscriptions; computer time and/or specialized software; and other justified research-specific needs. The early career fellowship program provides resources that a more established scientist would have acquired allowing

43 CFR 10010.9 - Apply NEPA early.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Apply NEPA early. 10010.9 Section 10010.9... Initiating the NEPA Process § 10010.9 Apply NEPA early. (a) The Commission will initiate early consultation... early with interested private parties and organizations, including when the Commission's own involvement...

Oil and gas: Oilfield class actions

DOE Office of Scientific and Technical Information (OSTI.GOV)

McArthur, J.B.

1997-06-01

The use of class actions is getting alot of attention in the oilfield. Plaintiffs have filed class actions challenging two of the most rooted industry practices, oil posted prices and deregulated natural gas affiliate deduction and charges. The classes will include tens or hundreds of thousands of plaintiffs and may transform two of the industry`s most settled practices. The emotions surrounding the class action risk obscuring the fact that it is an old and oft-used tool in oilfield litigation. The class action {open_quotes}provides a means by which, where a large group of persons are interested in a matter, one ormore » more may sue or be sued as representatives of the class without needing to join every member of the class.{close_quotes} The procedure avoids waste by combining scattered disputes, even if some injured might sue individually, and it enables plaintiffs who could not afford to sue to be represented anyway. The lawyers draw their fees from any recovery. Almost all oilpatch class actions are brought to resolve a {open_quotes}common question{close_quotes} under Federal Rules of Civil Procedure 23(b)(3) or state counterparts. The rule`s {open_quotes}opt-out{close_quotes} provisions give class actions a tremendous boost because members stay in unless they take steps to get out. This article discusses present and future class actions.« less

New bomb, no mission

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mello, G.

1997-05-01

The cold war may be over, but the nuclear arms race has not quite ended. The United States is fielding a new nuclear weapon-a bomb that was used to threaten Libya, a non-nuclear nation, even before it was deployed. The B61 {open_quotes}mod-11{close_quotes} gravity bomb is the first nuclear capability added to the US arsenal since 1989. It was developed and deployed secretly, without public or congressional debate, and in apparent contradiction to official domestic and international assurances that no new nuclear weapons were being developed in the United States. The B61-11`s unique earth-penetrating characteristic and wide range of yields allowmore » it to threaten otherwide indestructible targets from the air-or, in Pentagonese, to hold such targets {open_quotes}at risk.{close_quotes} That makes the B61-11 a uniquely useful warfighting tool. The 1,200-pound B61-11 replaces the B53, a 8,900-pound, nine-megaton bomb that was developed as a {open_quotes}city buster{close_quotes} and was later designated as a substitute for an earth-penetrating weapon. The B53 was deliverable only by vulnerable B-52s; in contrast, the smaller and lighter B61-11 can be delivered the the stealthier B-2A bomber, or even by F16 fighters.« less

Methanex sticks to its knitting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morris, G.D.L.

1997-04-30

Methanex was created just six years ago by the breakup of Ocelot Industries (Calgary, AB), a conglomerate with too many different business and too much debt. Those demons have since been banished, but management remains obsessive about focused, low-cost operations and a squeaky-clean balance sheet. The results show in a company that is generally admired, occasionally resented, and always speculated about. The top two questions are what it will do with its cash hoard,more » $$413 million as of first-quarter 1997, and when it will diversify. Pierre Choquette, who became president in December 1994, hears the questions often but says he is more amused by them than irritated, because the answers are so obvious. {open_quotes}We review the situation at every board meeting, but usually we prefer to have the liquid assets - it gives you a lot of advantages - and to reinvest in the core business,{close_quotes} says Choquette. {open_quotes}We paid $$275 million for our second plant in Chile, which we just completed, and the third one now under construction will cost about $300 million. I sit on a nonchemical company`s board, and we wonder at every downturn, {open_quote}How are we going to survive?{close_quote} [Having a cushion] is a lot nicer.{close_quotes}« less

Lethal pallister-killian syndrome: Phenotypic similarity with fryns syndrome

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ignacio Rodriquez, J.; Garcia, I.; Alvarez, J.

1994-11-01

The Pallister-Killian syndrome is a sporadic multiple congenital anomaly syndrome characterized by {open_quotes}coarse{close_quotes} face, profound mental retardation, and epilepsy. Chromosomes of peripheral lymphocytes are usually normal, but tissue cultures show varying degrees of mosaicism for isochromosome 12p. In babies who die neonatally of severe malformations, including diaphragmatic hernia, and who also have a {open_quotes}coarse{close_quotes} face, acral hypoplasia, and other internal anomalies, Fryns syndrome is more likely to be suspected than Pallister-Killian syndrome, especially if karyotyping is unavailable or if peripheral lumphocytes have a normal chromosome constitution. An initial diagnosis of Fryns syndrome had to be modified in 3 successive newbornmore » infants since chromosome analysis or in situ hybridization with a chromosome 12 probe on kidney tissue demonstrated the mosaic aneuploidy characteristic of Pallister-Killian syndrome. These 3 patients confirm that a similar pattern of malformations can be present in both conditions at birth. It consists of {open_quotes}coarse{close_quotes} face, acral hypoplasia, diaphragmatic hernia, and other defects. Newborn infants who present this phenotype, but lack a conclusively normal chromosome test, may not have Fryns syndrome. A diagnosis of Fryns syndrome should be made carefully to avoid the risk of inappropriate genetic counseling. 31 refs., 10 figs., 1 tab.« less

Conversion of (Meth)acrylic acids to methane granular sludge: Initiation by specific anerobic microflora

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shtarkman, N.B.; Obraztova, A.Y.; Laurinavichyus, K.S.

1995-03-01

The role of a specific anaerobic microflora in the initiation of degradation of (meth)acrylic acids to methane by granular sludge from a UASB reactor was investigated. Associations of anaerobic bacteria isolated from the anaerobic sludge, which was used for a long time for treatment of wastewater from (meth)acrylate production, were able to realize the initial stage of (meth)acrylic acid decomposition, i.e., a conversion of acrylic and methacrylic acids to propionic and isobutyric acids, respectively. When added to granules, these association played a role of an {open_quotes}initiator{close_quotes} of the degradation process, which was then continued by the granular sludge microflora utilizingmore » propionate and isobutyrate. Some characteristics of the granules adapted to propionate or isobutyrate are presented. The rates of propionate and isobutyrate consumption by adapted granules is, respectively, 21 and 53 times higher than the values obtained for nonadapted granules. A combined use of {open_quotes}initiating{close_quotes} bacteria and adapted granules provided degradation of (meth)acrylic acids with a maximum methane yield. The possibility is discussed of employing the granules, which are adapted to short-chain fatty acids, and the {open_quotes}initiating{close_quotes} bacteria, which accomplish the initial steps of the organic material decomposition to lower fatty acids, for the conversion of various chemical compounds to methane. 10 refs., 3 figs., 2 tabs.« less

Green electricity: It`s in the eye of the beholder

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rodgers, L.M.

Some people want to know what {open_quotes}green power{close_quotes} means - and, by extension, {open_quotes}environmentally friendly{close_quotes}. Does that mean low emissions, including nuclear energy? Is renewable energy automatically green? Should the simple fact of compliance with all standards imposed by the Environmental Protection Agency afford the right to advertise power generation as green? Consumers, agencies and state and federal officials want truth in advertising. Proponents of alternative generation claim consumers are willing to pay more for cleaner, greener energy. Residential customers of Detroit Edison, for instance, pay more than $6.50 additional per month to support solar energy. In Colorado, the Governor`smore » Office of Energy Conservation is using special funds to help offset the additional cost it takes to power the governors` home with wind. Only clear industry guidelines can ensure that everyone is actually getting what they`re paying for. Green power certification is proceeding on several different fronts. Commissions and legislatures are mandating resource disclosure of generation sources. Legislation at both the state and federal level are investigating the use of renewable portfolio standards. The Federal Trade Commission is considering establishing voluntary guidelines for electricity advertising like those already established for other retail products in the FTCs 1992 {open_quotes}Guides for the Use of Environmental Marketing Claims{close_quotes} (16 CFR 260).« less

Critical fiber length technique for composite manufacturing processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sivley, G.N.; Vandiver, T.L.; Dougherty, N.S.

1996-12-31

An improved injection technique for composite structures has been cooperatively developed by the U.S. Army Missile Command (MICOM) and Rockwell International (RI). This process simultaneously injects chopped fiberglass fibers and an epoxy resin matrix into a mold. Four injection techniques: (1){open_quotes}Little Willie{close_quotes} RTM system, (2) Pressure Vat system, (3) Pressure Vat system with vacuum assistance, and (4) Injection gun system, were investigated for use with a 304.8 mm x 304.8 mm x 5.08 mm (12 in x 12 in x 0.2 in) flat plaque mold. The driving factors in the process optimization included: fiber length, fiber weight, matrix viscosity, injectionmore » pressure, flow rate, and tool design. At fiber weights higher than 30 percent, the injection gun appears to have advantages over the other systems investigated. Results of an experimental investigation are reviewed in this paper. The investigation of injection techniques is the initial part of the research involved in a developing process, {open_quotes}Critical Fiber Length Technique{close_quotes}. This process will use the data collected in injection experiment along with mechanical properties derived from coupon test data to be incorporated into a composite material design code. The {open_quotes}Critical Fiber Length Technique{close_quotes} is part of a Cooperative Research and Development Agreement (CRADA) established in 1994 between MICOM and RI.« less

Physical and transcriptional map in the CMT 1A region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chevillard, C.; Passage, E.; Cudrey, C.

1994-09-01

The Charcot-Marie-Tooth disease type 1A (CMT1A) has been mapped to the proximal short arm of chromosome 17. CMT1A is the most frequent of the motor and sensory peripheral neuropathies and is associated with a duplication of a 1.5 Mb fragment in proximal 17p12. Several groups have proposed that the gene coding for peripheral myelin protein-22 (PMP-22) as the candidate gene for CMT1A. We have recently published a {open_quote}MegaYAC{close_quote} contig of 6 Mb which covers the CMT1A critical region. In order to isolate new genes localized in this region, we used a {open_quote}physical trapping {close_quote} strategy derived from the direct cDNAmore » selection technique developed by Parimoo et al. This approach has allowed us to construct cDNA {open_quotes}minilibraries{close_quotes} using YAC DNA from the CMT1A region. One of the clones in these minilibraries has been mapped back to the CMT1A duplication. Other potentially interesting clones are in the process of further characterization. Furthermore, we have mapped several Genethon microsatellites in the 6 Mb YAC contig and some are located in the CMT1A duplicated region. These highly polymorphic markers should prove useful for diagnostic testing in CMT1A.« less

Multifunction devices and their impacts on energy use

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amorosano, D.

1995-12-01

Integrated multifunctional office equipment will have ramifications for energy efficiency and use. Specifically discussed here is Canon`s Digital Imaging System, also known as the GP55 Series, currently under development. Integrated office equipment combines the capabilities of single-function, stand-alone devices, increasing efficiency by eliminating steps in the production and distribution of documents. Canon and other vendors are now introducing these products into the office equipment industry in response to four trends: (1) Implementation of local area networks (LANs). It`s estimated that by 1997, 73% of all personal computers (PCs) in offices will be networked in some way. Vendors are looking tomore » tie their office equipment into that network connection and shared-resource capability. (2) Adoption of the {open_quotes}More with less{close_quotes} attitude by most companies is forcing new approaches to the way in which they increase efficiency. (3) Continuing workgroup requirements for both electronic and hard copy input/output capabilities. (4) Persistence of the {open_quotes}Sneaker{close_quotes} network. Research commissioned by Canon has shown that in spite of LAN penetration, this {open_quotes}Sneakernet{close_quotes} is still significant, meaning that users must still leave their desks an average of 11 times a day to make copies, send faxes, etc. The idea behind integrated technology is to eliminate those steps in the document processing procedure.« less

The enforcement provisions of the Clean Air Act - not the same old Section 113

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benthul, H.R.

1996-08-01

The Clean Air Act ({open_quotes}CAA{close_quotes}) of 1990 was in many respects a major overhaul of the previous versions of the Clean Air Act although it retained most of the preexisting major programs such as the basic National Ambient Air Quality Standards ({open_quotes}NAAQS{close_quotes}) scheme, PSD, new source performance standards, regulation of toxic air pollutants, and the like. The 1990 Act strengthened the enforcement provisions of the Act by enhancing the enforcement powers of the Environmental Protection Agency ({open_quotes}EPA{close_quotes}) of {section}113. For example, the criminal enforcement provisions of {section}113 are expanded both in the range of punishment and in the kinds ofmore » activities which are subject to criminal enforcement. Moreover, the Act now contains a number of additional enforcement provisions in addition to those found in {section}113. The purpose of this paper is to discuss both the {section}113 provision and as well, identify those enforcement provisions found outside {section}113. The latter provisions will be taken up first and addressed by Titles of the Act. The discussion of specific sections and subsections of the CAA are necessarily brief and in the nature of highlighting of particular features; like the rest of the CAA, careful reading and analysis is a requirement for full understanding.« less

WWC Review of the Report "Early College, Early Success: Early College High School Initiative Impact Study." What Works Clearinghouse Single Study Review

ERIC Educational Resources Information Center

What Works Clearinghouse, 2014

2014-01-01

Early College High Schools partner with colleges and universities to provide students with an opportunity to earn an Associate's degree or college credits toward a Bachelor's degree at no or low cost to students. In a recent study, researchers found that attending Early College High Schools improved some high school and postsecondary outcomes for…

Michigan Early Adolescent Survey: Final Report.

ERIC Educational Resources Information Center

Keith, Joanne; And Others

This document contains the final report from the Michigan Early Adolescent Survey, a study undertaken to: (1) develop a profile of Michigan early adolescents that focused on out-of-school time and included biological, psychological, and sociological information; (2) develop a profile of families which included early adolescents; (3) assess the…

Challenges and Limitations in Early Intervention

ERIC Educational Resources Information Center

Hadders-Algra, Mijna

2011-01-01

Research over the past three decades has shown that early intervention in infants biologically at risk of developmental disorders, irrespective of the presence of a brain lesion, is associated with improved cognitive development in early childhood without affecting motor development. However, at present it is unknown whether early intervention is…

7 CFR 1717.901 - Early approval.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 11 2011-01-01 2011-01-01 false Early approval. 1717.901 Section 1717.901 Agriculture... for Supplemental Financing Required by 7 CFR 1710.110 § 1717.901 Early approval. (a) Conditions. If... supplemental financing early in the process, before funding is available for the concurrent RUS insured loan...

Early Interventions: Keys to Successful Readers.

ERIC Educational Resources Information Center

Jeffreys, JoAnn; Spang, Joan

This action research outlines an early reading intervention project for improving students' reading skills and promoting the implementation of early reading intervention programs. The targeted population includes first and second grade students in one school located in the suburbs of a major city in Illinois. The problem of early reading…

Early Childhood Services in New Zealand.

ERIC Educational Resources Information Center

Oborn, Glennie

2002-01-01

Describes the types and characteristics of New Zealand early childhood education services. Specific areas addressed include: (1) Te Whaariki, the New Zealand early childhood curriculum; (2) great outdoors as a feature of early education; (3) education and care centers; (4) kindergartens and playcenters; and (5) Te Kohanga Reo, Maori language and…

Early- versus Late-Onset Dysthymia

PubMed Central

Sansone, Lori A.

2009-01-01

In the current Diagnostic and Statistical Manual of Mental Disorders, dysthymic disorder is categorized as either early-onset or late-onset, based upon the emergence of symptoms before or after the age of 21, respectively. Does this diagnostic distinction have any meaningful clinical implications? In this edition of The Interface, we present empirical studies that have, within a single study, compared individuals with early-versus late-onset dysthymia. In this review, we found that, compared to those with late-onset dysthymia, early-onset patients are more likely to harbor psychiatric comorbidity both on Axis I and II, exhibit less psychological resilience, and have more prominent family loadings for mood disorders. These findings suggest that this distinction is meaningful and that the early-onset subtype of dysthymia is more difficult to effectively treat. PMID:20049145

Effect of socioeconomic status disparity on child language and neural outcome: how early is early?

PubMed

Hurt, Hallam; Betancourt, Laura M

2016-01-01

It is not news that poverty adversely affects child outcome. The literature is replete with reports of deleterious effects on developmental outcome, cognitive function, and school performance in children and youth. Causative factors include poor nutrition, exposure to toxins, inadequate parenting, lack of cognitive stimulation, unstable social support, genetics, and toxic environments. Less is known regarding how early in life adverse effects may be detected. This review proposes to elucidate "how early is early" through discussion of seminal articles related to the effect of socioeconomic status on language outcome and a discussion of the emerging literature on effects of socioeconomic status disparity on brain structure in very young children. Given the young ages at which such outcomes are detected, the critical need for early targeted interventions for our youngest is underscored. Further, the fiscal reasonableness of initiating quality interventions supports these initiatives. As early life adversity produces lasting and deleterious effects on developmental outcome and brain structure, increased focus on programs and policies directed to reducing the impact of socioeconomic disparities is essential.

Predicting Readmission at Early Hospitalization Using Electronic Clinical Data: An Early Readmission Risk Score.

PubMed

Tabak, Ying P; Sun, Xiaowu; Nunez, Carlos M; Gupta, Vikas; Johannes, Richard S

2017-03-01

Identifying patients at high risk for readmission early during hospitalization may aid efforts in reducing readmissions. We sought to develop an early readmission risk predictive model using automated clinical data available at hospital admission. We developed an early readmission risk model using a derivation cohort and validated the model with a validation cohort. We used a published Acute Laboratory Risk of Mortality Score as an aggregated measure of clinical severity at admission and the number of hospital discharges in the previous 90 days as a measure of disease progression. We then evaluated the administrative data-enhanced model by adding principal and secondary diagnoses and other variables. We examined the c-statistic change when additional variables were added to the model. There were 1,195,640 adult discharges from 70 hospitals with 39.8% male and the median age of 63 years (first and third quartile: 43, 78). The 30-day readmission rate was 11.9% (n=142,211). The early readmission model yielded a graded relationship of readmission and the Acute Laboratory Risk of Mortality Score and the number of previous discharges within 90 days. The model c-statistic was 0.697 with good calibration. When administrative variables were added to the model, the c-statistic increased to 0.722. Automated clinical data can generate a readmission risk score early at hospitalization with fair discrimination. It may have applied value to aid early care transition. Adding administrative data increases predictive accuracy. The administrative data-enhanced model may be used for hospital comparison and outcome research.

Early College for All: Efforts to Scale up Early Colleges in Multiple Settings

ERIC Educational Resources Information Center

Edmunds, Julie A.

2016-01-01

Given the positive impacts of the small, stand-alone early college model and the desire to provide those benefits to more students, organizations have begun efforts to scale up the early college model in a variety of settings. These efforts have been supported by the federal government, particularly by the Investing in Innovation (i3) program.…

Children with Special Needs: Lessons for Early Childhood Professionals. Early Childhood Education Series.

ERIC Educational Resources Information Center

Kostelnik, Marjorie J.; Onaga, Esther; Rohde, Barbara; Whiren, Alice

Bridging the gap between child development and strategies for inclusion, this book is intended to help early childhood practitioners and pre-service teachers feel better equipped to meet the needs of all the children in their early childhood setting. Each chapter of the book is a case study introducing a child (ages birth to 8 years) with one or…

Positioning and early mobilisation in stroke.

PubMed

Keating, Moira; Penney, Maree; Russell, Petra; Bailey, Emma

Stroke unit care, providing early rehabilitation, improves long-term outcomes for patients following a stroke. Early mobilisation and good positioning are recognised as key aspects of care in stroke units. Nurses working on stroke units have an important role because they are able to implement positioning and early mobilisation strategies 24 hours a day, reducing the risk of complications and improving functional recovery. Patients benefit if nurses work effectively with the therapy team in positioning and early mobilisation. Nurses also need appropriate training and expertise to make best use of specialist equipment.

Colorado Early Childhood Study.

ERIC Educational Resources Information Center

Colorado State Dept. of Education, Denver. Planning and Evaluation Unit.

The Colorado State Board of Education allocated Title IV-V funds in 1975 for a study of the status of early childhood education in Colorado. The purposes of the study were to: (1) gather data relevant to early childhood education on the status of all children from birth through age 5; (2) identify needs of children of this age within the state;…

Early College High Schools

ERIC Educational Resources Information Center

Dessoff, Alan

2011-01-01

For at-risk students who stand little chance of going to college, or even finishing high school, a growing number of districts have found a solution: Give them an early start in college while they still are in high school. The early college high school (ECHS) movement that began with funding from the Bill and Melinda Gates Foundation 10 years ago…

Survival After Early and Normal Retirement

ERIC Educational Resources Information Center

Haynes, Suzanne G.; And Others

1978-01-01

Describes an epidemiological study of the patterns and correlates of survival after early (age 62 to 64) and normal retirement (age 65). Death rates were significantly elevated during the first, fourth, and fifth years after early retirement. Pre-retirement health status was the only significant predictor of survival after early retirement.…

Leadership in Early Childhood Special Education

ERIC Educational Resources Information Center

Arora, Samita Berry

2013-01-01

With the demands of high quality early childhood special education programs within public school settings, there is a need to place emphasis on research and training regarding early childhood leaders and managers in this complex and diverse field. The focus of this research is to examine what early childhood special education (ECSE) leadership…

LLNL demonstration of liquid gun propellant destruction in a 0.1 gallon per minute scale reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cena, R.J.; Thorsness, C.B.; Coburn, T.T.

1994-06-01

The Lawrence Livermore National Laboratory (LLNL) has built and operated a pilot plant for processing oil shale using recirculating hot solids. This pilot plant, was adapted in 1993 to demonstrate the feasibility of decomposing a liquid gun propellant (LGP), LP XM46, a mixture of 76% HAN (NH{sub 3}OHNO{sub 3}) and 24% TEAN (HOCH{sub 2}CH{sub 2}){sub 3} NHNO{sub 3} diluted 1:3 in water. In the Livermore process, the LPG is thermally treated in a moving packed bed of ceramic spheres, where TEAN and HAN decompose, forming a suite of gases including: methane, carbon monoxide, oxygen, nitrogen oxides, ammonia and molecular nitrogen.more » The ceramic spheres are circulated and heated, providing the energy required for thermal decomposition. The authors performed an extended one day (8 hour) test of the solids recirculation system, with continuous injection of approximately 0.1 gal/min of LGP, diluted 1:3 in water, for a period of eight hours. The apparatus operated smoothly over the course of the eight hour run during which 144 kg of solution was processed, containing 36 kg of LGP. Continuous on-line gas analysis was invaluable in tracking the progress of the experiment and quantifying the decomposition products. The reactor was operated in two modes, a {open_quotes}Pyrolysis{close_quotes} mode, where decomposition products were removed from the moving bed reactor exit, passing through condensers to a flare, and in a {open_quotes}Combustion{close_quotes} mode, where the products were oxidized in air lift pipe prior to exiting the system. In the {open_quotes}Pyrolysis{close_quotes} mode, driver gases were recycled producing a small, concentrated stream of decomposition products. In the {open_quotes}Combustion mode{close_quotes}, the driver gases were not recycled, resulting in 40 times higher gas flow rates and correspondingly lower concentrations of nitrogen bearing gases.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, I.

Singapore`s Economic Development Board (EDB) will team up with Mobil and Exxon in separate feasibility studies for the country`s third steam cracker project. Mobil recently announced it had signed a memorandum of understanding with EDB and Jurong Town Corp. to study a Smore » $$1.5-billion project for an 800,000-m.t./year ethylene plant for completion in about 2001. Exxon now intends to launch its own parallel study, with EDB also involved. {open_quotes}Both feasibility studies will be carried out separately and at the same time,{close_quotes} an EDB spokesperson tells CW. {open_quotes}EDB, as a developmental agency, will provide Mobil and Exxon with the necessary facilitation and support.{close_quotes} Exxon`s original plan had been to study a slightly smaller cracker, with capacity of about 650,000 m.t./year. Both companies are involved in aromatics production in Singapore. Both cracker studies are expected to take 12-15 months to complete. Sources do not rule out the possibility of Mobil and Exxon then teaming up for the project or both US majors going ahead with their own plants. {open_quotes}Exxon Chemical is being considered as a possible partner in the third plant,{close_quotes} confirms EDB assistant managing director Gong Wee Lik. {open_quotes}More petrochemical complexes could be built if conditions remain favorable-there`s no reason to stop at three,{close_quotes} he adds. Singapore`s second ethylene plant, a joint venture involving Shell and a Japanese consortium, is already under construction and is scheduled to start production in 1997. Its initial planned capacity is for 428,000 m.t./year of ethylene and 214,000 m.t./year of propylene. The plant will be built on Pulau Ayer Merbau, which is the site of the existing S$$2-billion complex built in 1984 and producing 450,000 m.t./year of ethylene and 225,000 m.t./year of propylene.« less

Task 1.6 - mixed waste. Topical report, April 1, 1994--September 30, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

For fifty years, the United States was involved in a nuclear arms race of immense proportions. During the majority of this period, the push was always to design new weapons, produce more weapons, and increase the size of the arsenal, maintaining an advantage over the opposition in order to protect U.S. interests. Now that the {open_quotes}Cold War{close_quotes} is over, we are faced with the imposing tasks of dismantling, cleaning up, and remediating the wide variety of problems created by this arms race. An overview of the current status of the total remediation effort within the DOE is presented in themore » DOE publication {open_quotes}ENVIRONMENTAL MANAGEMENT 1995{close_quotes} (EM 1995). Not all radioactive waste is the same though; therefore, a system was devised to categorize the different types of radioactive waste. These categories are as follows: spent fuel; high-level waste; transuranic waste; low-level waste; mixed waste; and uranium-mill tailings. Mixed waste is defined to be material contaminated with any of these categories of radioactive material plus an organic or heavy metal component. However, for this discussion, {open_quotes}mixed waste{close_quote} will pertain only to low-level mixed waste which consists of low-level radioactive waste mixed with organic solvents and or heavy metals. The area of {open_quotes}mixed-waste characterization, treatment, and disposal{close_quotes} is listed on page 6 of the EM 1995 publication as one of five focus areas for technological development, and while no more important than the others, it has become an area of critical concern for DOE. Lacking adequate technologies for treatment and disposal, the DOE stockpiled large quantities of mixed waste during the 1970s and 1980s. Legislative changes and the need for regulatory compliance have now made it expedient to develop methods of achieving final disposition for this stockpiled mixed waste.« less

75 FR 2176 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-14

...) whether the SLP has met the 3% average or more quoting requirement (the ``Quoting Requirement'') in Rule... amending it to specify that the current SLP liquidity credits apply only to transactions in securities with...

78 FR 62887 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... market participant to jump ahead of another market participant's quoted price by a de minimis amount, and... market participant to jump ahead of another market participant's quoted price by a de minimis amount, and...

29 CFR 553.225 - Early relief.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false Early relief. 553.225 Section 553.225 Labor Regulations... Enforcement Employees of Public Agencies Tour of Duty and Compensable Hours of Work Rules § 553.225 Early... employees on the previous shift prior to the scheduled starting time. Such early relief time may occur...

29 CFR 553.225 - Early relief.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Early relief. 553.225 Section 553.225 Labor Regulations... Enforcement Employees of Public Agencies Tour of Duty and Compensable Hours of Work Rules § 553.225 Early... employees on the previous shift prior to the scheduled starting time. Such early relief time may occur...

Processes of early stroke care and hospital costs.

PubMed

Svendsen, Marie Louise; Ehlers, Lars H; Hundborg, Heidi H; Ingeman, Annette; Johnsen, Søren P

2014-08-01

The relationship between processes of early stroke care and hospital costs remains unclear. We therefore examined the association in a population based cohort study. We identified 5909 stroke patients who were admitted to stroke units in a Danish county between 2005 and 2010.The examined recommended processes of care included early admission to a stroke unit, early initiation of antiplatelet or anticoagulant therapy, early computed tomography/magnetic resonance imaging (CT/MRI) scan, early physiotherapy and occupational therapy, early assessment of nutritional risk, constipation risk and of swallowing function, early mobilization,early catheterization, and early thromboembolism prophylaxis.Hospital costs were assessed for each patient based on the number of days spent in different in-hospital facilities using local hospital charges. The mean costs of hospitalization were $23 352 (standard deviation 27 827). The relationship between receiving more relevant processes of early stroke care and lower hospital costs followed a dose–response relationship. The adjusted costs were $24 566 (95% confidence interval 19 364–29 769) lower for patients who received 75–100% of the relevant processes of care compared with patients receiving 0–24%. All processes of care were associated with potential cost savings, except for early catheterization and early thromboembolism prophylaxis. Early care in agreement with key guidelines recommendations for the management of patients with stroke may be associated with hospital savings.

Electrokinetic decontamination of concrete. Final report, August 3, 1993--September 15, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-12-31

The ELECTROSORB{reg_sign} {open_quotes}C{close_quotes} process is an electrokinetic process for decontaminating concrete. ELECTROSORB{reg_sign} {open_quotes}C{close_quotes} uses a carpet-like extraction pad which is placed on the contaminated concrete surface. An electrolyte solution is circulated from a supporting module. This module keeps the electrolyte solution clean. The work is advancing through the engineering development stage with steady progress toward a full scale demonstration unit which will be ready for incorporation in the DOE Large Scale Demonstration Program by Summer 1997. A demonstration was carried out at the Mound Facility in Miamisburg, Ohio, in June 1996. Third party verification by EG&G verified the effectiveness ofmore » the process. Results of this work and the development work that proceeded are described herein.« less

LLNL Small-Scale Friction sensitivity (BAM) Test

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simpson, L.R.; Foltz, M.F.

1996-06-01

Small-scale safety testing of explosives, propellants and other energetic materials, is done to determine their sensitivity to various stimuli including friction, static spark, and impact. Testing is done to discover potential handling problems for either newly synthesized materials of unknown behavior, or materials that have been stored for long periods of time. This report describes the existing {open_quotes}BAM{close_quotes} Small-Scale Friction Test, and the methods used to determine the friction sensitivity pertinent to handling energetic materials. The accumulated data for the materials tested is not listed here - that information is in a database. Included is, however, a short list ofmore » (1) materials that had an unusual response, and (2), a few {open_quotes}standard{close_quotes} materials representing the range of typical responses usually seen.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, M.

The European chemical industry, facing growing political support for the European Commission`s latest version of the carbon dioxide (CO{sub 2})-energy tax, has renewed its attacks on the proposed law. Simon de Bree, chairman of DSM and president of the European Chemical Industry Council (Cefic; Brussels), last week wrote to Jacques Santer, president of the commission, and Solana Madariaga, current president of Europe Union`s (EU) Council of Ministers, saying the tax was {open_quotes}totally unacceptable and irresponsible in terms of EU competitiveness.{close_quotes} He says it {open_quotes}has nothing to do anymore with the protection of the environment and has instead become a normalmore » additional taxation, disguised, for opportunistic reasons, as an environmental protection measurement.{close_quotes}« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grabow, P.C.

It is apparent that the computer has had and is having a profound effect on everyone`s life. However, it is not always apparent what these effects are, where they originate, what direction they are taking us, or what controls them. Unfortunately, discussions concerning these issues often lack needed context -- terminology and ideas that help one uncover the underlying reality. This paper attempts to provide some of that context by introducing Jacques Ellul`s concept of {open_quotes}technique{close_quotes} -- encompassing much more than the computer. Many of these ideas grew out of {open_quotes}The Cultural Impact of the Computer{close_quotes}, a senior-level course taughtmore » by the author at Baylor University. The need for such context became evident when preparing for that course.« less

Tendency towards maximum complexity in a nonequilibrium isolated system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Calbet, Xavier; Lopez-Ruiz, Ricardo

2001-06-01

The time evolution equations of a simplified isolated ideal gas, the {open_quotes}tetrahedral{close_quotes} gas, are derived. The dynamical behavior of the Lopez-Ruiz{endash}Mancini{endash}Calbet complexity [R. Lopez-Ruiz, H. L. Mancini, and X. Calbet, Phys. Lett. A >209, 321 (1995)] is studied in this system. In general, it is shown that the complexity remains within the bounds of minimum and maximum complexity. We find that there are certain restrictions when the isolated {open_quotes}tetrahedral{close_quotes} gas evolves towards equilibrium. In addition to the well-known increase in entropy, the quantity called disequilibrium decreases monotonically with time. Furthermore, the trajectories of the system in phase space approach themore » maximum complexity path as it evolves toward equilibrium.« less

De novo direct duplication of chromosome segment 22q11.2-q13.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fujimoto, Atsuko; Lin, Ming S.

Lindsay et al. [1995] reported a case of de novo duplication of the segment 22q11-q12. Molecular cytogenetics studies showed that the segment includes the regions responsible for the {open_quotes}cat eye,{close_quotes} DiGeorge, and velo-cardio-facial syndrome, and extends distal to the breakpoint cluster region. The phenotype was milder than that of complete trisomy 22 and der(22)t(11;22) (q23;q11) syndrome and was similar in type and severity to that of {open_quotes}cat eye{close_quotes} syndrome (CES). They suggested that trisomy of gene(s) responsible for the CES might have a predominant phenotypic effect over other genes present in the region duplicated in their patient. 3 refs., 2more » figs.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rotman, D.

Exxon chemical says it has made linear low-density polyethylene (LLDPE) using metallocene catalysts at its world-scale gas-phase plant in Mont Belvieu, TX. Exxon also says it has received a broad US patent that covers the use of metallocenes in gas-phase reactors that use condensing mode technology and that it plans to license the know-how. The moves, say industry experts, greatly strengthen Exxon`s position in metallocenes, particularly in pushing metallocene-based PE into commodity markets. The use of gas-phase technology {open_quotes}had to happen{close_quotes} to allow metallocene polymers to compete as commodities, says David Highfield, v.p. at Catalyst Consultants (Spring House, PA). {open_quotes}It`smore » very important and very significant in widening the scope of [metallocene] technology.{close_quotes}« less

[Autism: An early neurodevelopmental disorder].

PubMed

Bonnet-Brilhault, F

2017-04-01

With approximately 67 million individuals affected worldwide, autism spectrum disorder (ASD) is the fastest growing neurodevelopmental disorder (United Nations, 2011), with a prevalence estimated to be 1/100. In France ASD affects approximately 600,000 individuals (from childhood to adulthood, half of whom are also mentally retarded), who thus have a major handicap in communication and in adapting to daily life, which leads autism to be recognized as a national public health priority. ASD is a neurodevelopmental disorder that affects several domains (i.e., socio-emotional, language, sensori-motor, executive functioning). These disorders are expressed early in life with an age of onset around 18 months. Despite evidence suggesting a strong genetic link with ASD, the genetic determinant remains unclear. The clinical picture is characterized by impairments in social interaction and communication and the presence of restrictive and repetitive behaviors (DSM-5, ICD-10). However, in addition to these two main dimensions there is significant comorbidity between ASD and other neurodevelopmental disorders such as attention deficit hyperactivity disorder or with genetic and medical conditions. One of the diagnostic features of ASD is its early emergence: symptoms must begin in early childhood for a diagnosis to be given. Due to brain plasticity, early interventions are essential to facilitate clinical improvement. Therefore, general practitioners and pediatricians are on the front line to detect early signs of ASD and to guide both medical explorations and early rehabilitation. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Evaluating and Supporting Early Childhood Teachers

ERIC Educational Resources Information Center

Passe, Angèle Sancho

2015-01-01

There's a lot of conversation in the early childhood community on evaluating teachers to improve their performance. Raising the quality of early care and education is a priority for policymakers and practitioners on local, state, and federal levels. As a result, much attention is being focused on early childhood educators to ensure that they do a…

Early Detection | Division of Cancer Prevention

Cancer.gov

[[{"fid":"171","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Early Detection Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Early Detection Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","field_deltas":{"1":{"format":"default","field_file_image_alt_text[und][0][value]":"Early

37 CFR 1.219 - Early publication.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Early publication. 1.219... Applications § 1.219 Early publication. Applications that will be published under § 1.211 may be published earlier than as set forth in § 1.211(a) at the request of the applicant. Any request for early publication...

37 CFR 1.219 - Early publication.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Early publication. 1.219... Applications § 1.219 Early publication. Applications that will be published under § 1.211 may be published earlier than as set forth in § 1.211(a) at the request of the applicant. Any request for early publication...

Early Restoration | NOAA Gulf Spill Restoration

Science.gov Websites

Early Restoration Plan. On April 20, 2011 we reached an agreement with BP to start restoration planning draft plan for the third phase of early restoration in December 2013. We are considering your comments : All Phase III information and documents Phase II Useful Links: Phase II Early Restoration Plan &

Sprites and Early ionospheric VLF perturbations

NASA Astrophysics Data System (ADS)

Haldoupis, Christos; Amvrosiadi, Nino; Cotts, Ben; van der Velde, Oscar; Chanrion, Olivier; Neubert, Torsten

2010-05-01

Past studies have shown a correlation between sprites and early VLF perturbations, but the reported correlation varies widely from ~ 50% to 100%. The present study resolves these large discrepancies by analyzing several case studies of sprite and narrowband VLF observations, in which multiple transmitter-receiver VLF links with great circle paths (GCPs) passing near a sprite-producing thunderstorm were available. In this setup, the multiple links act in a complementary way that makes the detection of early VLF perturbations much more probable compared to a single VLF link that can miss several of them, a fact that was overlooked in past studies. The evidence shows that sprites are accompanied by early VLF perturbations in a one-to-one correspondence. This implies that the sprite generation mechanism may cause also sub-ionospheric conductivity disturbances that produce early VLF events. However, the one-to-one "sprite to early" event relationship, if viewed conversely as "early to sprite", appears not to be always reciprocal. This is because the number of early events detected in some cases was considerably larger than the number of sprites. Since the great majority of the early events not accompanied by sprites was caused by positive cloud to ground (+CG) lightning discharges, it is possible that sprites or sprite halos were concurrently present in these events as well but were missed by the sprite-watch detection system. In order for this option to be resolved we need more studies using highly sensitive optical systems capable of detecting weaker sprites, sprite halos and elves.

Early recognition of growth abnormalities permitting early intervention

USDA-ARS?s Scientific Manuscript database

Normal growth is a sign of good health. Monitoring for growth disturbances is fundamental to children's health care. Early detection and diagnosis of the causes of short stature allows management of underlying medical conditions, optimizing attainment of good health and normal adult height. This rev...

Integrating Computer Technology in Early Childhood Education Environments: Issues Raised by Early Childhood Educators

ERIC Educational Resources Information Center

Wood, Eileen; Specht, Jacqueline; Willoughby, Teena; Mueller, Julie

2008-01-01

The purpose of this study was to assess the educators' perspectives on the introduction of computer technology in the early childhood education environment. Fifty early childhood educators completed a survey and participated in focus groups. Parallels existed between the individually completed survey data and the focus group discussions. The…

Integrating partner professionals. The Early Explorers project: Peers Early Education Partnership and the health visiting service.

PubMed

Barlow, J; Coe, C

2013-01-01

  A range of voluntary sector organizations are involved in the delivery of services to children, particularly within the Early Year's sector and children's centres. Peers Early Education Partnership (PEEP) Early Explorers project is one example of the way in which explicit partnerships are being forged across statutory and voluntary sectors with the aim of improving outcomes for children and families. This paper reports an exploration of stakeholder views and experiences of two Early Explorer clinics located in areas of high deprivation.   Semi-structured interviews were conducted with a purposive sample of stakeholders (n= 25) from children's centres, PEEP, the health visiting service and service users. Data were fully transcribed and analysed using a thematic approach.   The data suggest that the two key groups of stakeholders providing Early Explorer clinics (i.e. health visitors and PEEP practitioners) had quite different objectives in terms of their early goals for the clinic, but that despite these differences good progress was achieved in terms of working together effectively. All stakeholders including service users referred to the presence of PEEP as having improved the quality of the clinic environment, and participating mothers identified a wide range of benefits from the enhanced service. However, somewhat restricted views about the role of practitioners within the clinics were identified by users, and the findings suggest that although the early goals for the clinic had been exceeded, these may have been limited in terms of true 'partnership' working.   Early Explorer clinics appeared to have enhanced the service provided within traditional child health clinics and to have provided practitioners with access to hard-to-reach families and parents with access to services that are consistent with the broader policy aims of improving parent-infant interaction. However, questions remain as to whether the benefit of 'partnership' working was fully

Early anthropometric indices predict short stature and overweight status in a cohort of Peruvians in early adolescence

PubMed Central

Sterling, Robie; Miranda, J Jaime; Gilman, Robert H; Cabrera, Lilia; Sterling, Charles R; Bern, Caryn; Checkley, William

2014-01-01

While childhood malnutrition is associated with increased morbidity and mortality, less well understood is how early childhood growth influences height and body composition later in life. We revisited 152 Peruvian children who participated in a birth cohort study between 1995 and 1998, and obtained anthropometric and bioimpedance measurements 11 to 14 years later. We used multivariable regression models to study the effects of childhood anthropometric indices on height and body composition in early adolescence. Each standard deviation decrease in length-for-age at birth was associated with a decrease in adolescent height-for-age of 0.7 SD in both boys and girls (all p<0.001) and 9.7 greater odds of stunting (95% CI 3.3 to 28.6). Each SD decrease in length-for-age in the first 30 months of life was associated with a decrease in adolescent height-for-age of 0.4 in boys and 0.6 standard deviation in girls (all p<0.001) and with 5.8 greater odds of stunting (95% CI 2.6 to 13.5). The effect of weight gain during early childhood on weight in early adolescence was more complex to understand. Weight-for-length at birth and rate of change in weight-for-length in early childhood were positively associated with age- and sex-adjusted body mass index and a greater risk of being overweight in early adolescence. Linear growth retardation in early childhood is a strong determinant of adolescent stature, indicating that, in developing countries, growth failure in height during early childhood persists through early adolescence. Interventions addressing linear growth retardation in childhood are likely to improve adolescent stature and related-health outcomes in adulthood. PMID:22552904

Early anthropometric indices predict short stature and overweight status in a cohort of Peruvians in early adolescence.

PubMed

Sterling, Robie; Miranda, J Jaime; Gilman, Robert H; Cabrera, Lilia; Sterling, Charles R; Bern, Caryn; Checkley, William

2012-07-01

While childhood malnutrition is associated with increased morbidity and mortality, less well understood is how early childhood growth influences height and body composition later in life. We revisited 152 Peruvian children who participated in a birth cohort study between 1995 and 1998, and obtained anthropometric and bioimpedance measurements 11-14 years later. We used multivariable regression models to study the effects of childhood anthropometric indices on height and body composition in early adolescence. Each standard deviation decrease in length-for-age at birth was associated with a decrease in adolescent height-for-age of 0.7 SD in both boys and girls (all P < 0.001) and 9.7 greater odds of stunting (95% CI 3.3-28.6). Each SD decrease in length-for-age in the first 30 months of life was associated with a decrease in adolescent height-for-age of 0.4 in boys and 0.6 standard deviation in girls (all P < 0.001) and with 5.8 greater odds of stunting (95% CI 2.6-13.5). The effect of weight gain during early childhood on weight in early adolescence was more complex to understand. Weight-for-length at birth and rate of change in weight-for-length in early childhood were positively associated with age- and sex-adjusted body mass index and a greater risk of being overweight in early adolescence. Linear growth retardation in early childhood is a strong determinant of adolescent stature, indicating that, in developing countries, growth failure in height during early childhood persists through early adolescence. Interventions addressing linear growth retardation in childhood are likely to improve adolescent stature and related-health outcomes in adulthood. Copyright © 2012 Wiley Periodicals, Inc.

[Early flat colorectal cancer].

PubMed

Castelletto, R H; Chiarenza, C; Ottino, A; Garay, M L

1991-01-01

We report three cases of flat early colorectal carcinoma which were detected during the examination of 51 surgical specimens of colorectal resection. Two of them were endoscopically diagnosed, but the smallest one was not seen in the luminal instrumental examination. From the bibliographic analysis and our own experience we deduce the importance of flat lesions in the development of early colorectal carcinoma, either originated from pre-existent adenoma or de novo. Flat variants of adenoma, and presumably flush or depressed ones, must be considered as important factors in the early sequence adenoma-cancer. An appropriate endoscopic equipment with employment of additional staining techniques (such as carmine indigo and methylene blue) and the correct investigation during inflation-deflation procedures facilitates the identification of small lesions, their eradication and prevention from advanced forms of colorectal carcinoma.

[The early pregnancy factor (EPF) as an early marker of disorders in pregnancy].

PubMed

Straube, W; Römer, T; Zeenni, L; Loh, M

1995-01-01

The early pregnancy factor (EPF) seems to be very helpful in clinical applications such as early detection of pregnancy, differential diagnosis of failure of fertilization or implementation and prognosis of a fertilized ovum. Our purpose was to investigate the diagnostic value of single and serial measurement of EPF, especially in the differential diagnosis of abortion and extrauterine pregnancy. Women with a history of 6-16 weeks amenorrhoea with/without vaginal bleeding were included in the prospective study. The EPF-test system was carried out by means of the rosette inhibition method. EPF proved to be always positive in normal pregnant women and always negative in nonpregnant controls. In case of threatened abortion the prognosis was good, when the EPF values were positive, and poor when they became negative. Patients suffering from spontaneous and missed abortion mostly showed negative EPF-values. This was also true in ectopic pregnancies. The sensitivity and specificity of EPF-test system were 83%. The positive predictive value was observed to be 54% and the negative predictive value 95%. The EPF as an early embryonic signal may be a suitable parameter for the clinical use detecting pregnancy disturbances very early.

Marital conflict and early adolescents' self-evaluation: the role of parenting quality and early adolescents' appraisals.

PubMed

Siffert, Andrea; Schwarz, Beate; Stutz, Melanie

2012-06-01

Cognitive appraisals and family dynamics have been identified as mediators of the relationship between marital conflict and children's adjustment. Surprisingly little research has investigated both meditational processes in the same study. Guided by the cognitive-contextual framework and the spillover hypothesis, the present study integrated factors from both theories early adolescents' appraisals of threat and self-blame, as well as perceived parenting quality as mediators of the link between early adolescents' perception of marital conflict and their self-evaluations (self-esteem and scholastic competence). Analyses were based on the first two waves of an ongoing longitudinal study. Participants were 176 two-parent families, and their early adolescents (50.5% girls) whose mean age was 10.61 years at Time 1 (SD =0.40) and 11.63 years at Time 2 (SD=0.39). Structural equation modeling analyses indicated that parenting quality and early adolescents' perceived threat provided indirect pathways between marital conflict and early adolescents' self-esteem 1 year later when controlling for their initial level of self-esteem. With respect to scholastic competence, only fathers' parenting was an indirect link. Self-blame did not play a role. Implications for understanding the mechanisms by which exposure to marital conflict predicts early adolescents' maladjustment are discussed.

FFTF Asbestos Location Tracking Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reynolds, J.A.

1994-09-15

An Asbestos Location Tracking Program was prepared to list, locate, and determine Asbestos content and to provide baseline {open_quotes}good faith{close_quotes} for yearly condition inspections for the FFTF Plant and buildings and grounds.

75 FR 71163 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-22

... current quote traffic, although changes in market maker quoting behavior may reduce that increase by up to... public in accordance with the provisions of 5 U.S.C. 552, will be available for website viewing and...

Capturing early signs of deterioration: the dutch-early-nurse-worry-indicator-score and its value in the Rapid Response System.

PubMed

Douw, Gooske; Huisman-de Waal, Getty; van Zanten, Arthur R H; van der Hoeven, Johannes G; Schoonhoven, Lisette

2017-09-01

To determine the predictive value of individual and combined dutch-early-nurse-worry-indicator-score indicators at various Early Warning Score levels, differentiating between Early Warning Scores reaching the trigger threshold to call a rapid response team and Early Warning Score levels not reaching this point. Dutch-early-nurse-worry-indicator-score comprises nine indicators underlying nurses' 'worry' about a patient's condition. All indicators independently show significant association with unplanned intensive care/high dependency unit admission or unexpected mortality. Prediction of this outcome improved by adding the dutch-early-nurse-worry-indicator-score indicators to an Early Warning Score based on vital signs. An observational cohort study was conducted on three surgical wards in a tertiary university-affiliated teaching hospital. Included were surgical, native-speaking, adult patients. Nurses scored presence of 'worry' and/or dutch-early-nurse-worry-indicator-score indicators every shift or when worried. Vital signs were measured according to the prevailing protocol. Unplanned intensive care/high dependency unit admission or unexpected mortality was the composite endpoint. Percentages of 'worry' and dutch-early-nurse-worry-indicator-score indicators were calculated at various Early Warning Score levels in control and event groups. Entering all dutch-early-nurse-worry-indicator-score indicators in a multiple logistic regression analysis, we calculated a weighted score and calculated sensitivity, specificity, positive predicted value and negative predicted value for each possible total score. In 3522 patients, 102 (2·9%) had an unplanned intensive care/high dependency unit admissions (n = 97) or unexpected mortality (n = 5). Patients with such events and only slightly changed vital signs had significantly higher percentages of 'worry' and dutch-early-nurse-worry-indicator-score indicators expressed than patients in the control group. Increasing number

Early Rockets

NASA Image and Video Library

2004-04-15

In addition to Dr. Robert Goddard's pioneering work, American experimentation in rocketry prior to World War II grew, primarily in technical societies. This is an early rocket motor designed and developed by the American Rocket Society in 1932.

Telomere length and early severe social deprivation: linking early adversity and cellular aging

PubMed Central

Drury, SS; Theall, K; Gleason, MM; Smyke, AT; De Vivo, I; Wong, JYY; Fox, NA; Zeanah, CH; Nelson, CA

2012-01-01

Accelerated telomere length attrition has been associated with psychological stress and early adversity in adults; however, no studies have examined whether telomere length in childhood is associated with early experiences. The Bucharest Early Intervention Project is a unique randomized controlled trial of foster care placement compared with continued care in institutions. As a result of the study design, participants were exposed to a quantified range of time in institutional care, and represented an ideal population in which to examine the association between a specific early adversity, institutional care and telomere length. We examined the association between average relative telomere length, telomere repeat copy number to single gene copy number (T/S) ratio and exposure to institutional care quantified as the percent of time at baseline (mean age 22 months) and at 54 months of age that each child lived in the institution. A significant negative correlation between T/S ratio and percentage of time was observed. Children with greater exposure to institutional care had significantly shorter relative telomere length in middle childhood. Gender modified this main effect. The percentage of time in institutional care at baseline significantly predicted telomere length in females, whereas the percentage of institutional care at 54 months was strongly predictive of telomere length in males. This is the first study to demonstrate an association between telomere length and institutionalization, the first study to find an association between adversity and telomere length in children, and contributes to the growing literature linking telomere length and early adversity. PMID:21577215

Unlocking the Future: Early Literacy.

ERIC Educational Resources Information Center

Blair, Leslie Asher, Ed.

1999-01-01

This newsletter of the Southwest Educational Development Laboratory (SEDL)contains a collection of articles which discuss various aspects of early literacy. Articles in the newsletter are: "Introduction: Reading Instruction, a Key to the Future"; "Ensuring Early Literacy through Coherent Instruction" (Leslie Blair);…

Early extubation after cardiac surgery: emotional status in the early postoperative period.

PubMed

Silbert, B S; Santamaria, J D; Kelly, W J; O'brien, J L; Blyth, C M; Wong, M Y; Allen, N B

2001-08-01

To compare the emotional state during the first 3 days after coronary artery surgery of patients who had undergone early versus conventional extubation. A prospective, randomized, controlled trial. University hospital, single center. Eligible patients (n = 100) presenting for elective coronary artery surgery, randomized to an early extubation group or a conventional extubation group. Emotional status was measured by the Hospital Anxiety and Depression Scale (HAD), the Self Assessment Manikin (SAM), and the Multiple Affect Adjective Check List-Revised (MAACL-R). Tests were administered preoperatively and on the 1st and 3rd days postoperatively. Of patients in the conventional extubation group, 30% showed moderate-to-severe depressive symptoms (HAD score >10) on day 3 postoperatively compared with 8% of patients in the early extubation group (p = 0.02). There was a clinically insignificant increase in MAACL-R depression score on the 1st postoperative day within both groups but no other differences within or between groups in SAM or MAACL-R scores. Early extubation results in fewer patients displaying depressive symptoms on the 3rd postoperative day but appears to have little effect on other measurements of emotional status. Anesthetic management during coronary artery bypass graft surgery may play an important role in the overall well-being of the patient by decreasing the incidence of postoperative depression. Copyright 2001 by W.B. Saunders Company.

{open_quotes}In close proximity{close_quotes} to E&P waste management facilities: Lessons of three communities in the Four Corners Area

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shuey, C.

1994-12-31

Contaminant releases from E&P waste management facilities located near residences in three communities in the Four Corners Area -- two in New Mexico and one in Utah -- spurred vocal concern among local residents in recent years. Noxious odors, including hydrogen sulfide, were present in all cases and releases of production wastes and oil spills were prevalent in two of the cases. In all three, residents said they felt powerless to change operator or agency decisions about siting of facilities close to places where people congregate. These cases illustrate the need for regulators to consider facility locations in permitting decisions.more » They also demonstrate the need for creation of statutorily recognized buffer zones around new oil and gas production and processing facilities where releases of pollutants to the air, land and water can reasonably be expected, regardless of the level of pollution control. Buffer zones may be especially important in states where local governments have not elected to adopt land use and zoning requirements that affect the siting of E&P facilities. Agency and corporate sensitivity to siting concerns will engender public confidence in permitting decisions and avoid the needless waste of public and private resources.« less

Erratum: ``CO Line Width Differences in Early Universe Molecular Emission-Line Galaxies: Submillimeter Galaxies versus QSO Hosts'' (AJ, 131, 2763 [2006])

NASA Astrophysics Data System (ADS)

Carilli, C. L.; Wang, Ran

2006-11-01

It has been pointed out to us that in three dimensions the mean angle of randomly oriented disks with respect to the sky plane is <θ>=30deg, and not the 45° assumed in the original paper. This lower angle for the (assumed) random distribution of submillimeter galaxies, coupled with the factor of 2.3 lower mean CO line width for high-z, far-IR-luminous QSO host galaxies relative to the submillimeter galaxies, implies a mean angle with respect to the sky plane for the QSO host galaxies of <θ>QSO=13deg, as opposed to the 18° quoted in the original paper. We thank Pat Hall for bringing this to our attention.

Couple Therapy with Veterans: Early Improvements and Predictors of Early Dropout.

PubMed

Fischer, Melanie S; Bhatia, Vickie; Baddeley, Jenna L; Al-Jabari, Rawya; Libet, Julian

2017-07-28

Family services within Veterans Affairs Medical Centers fulfill an important role in addressing relationship distress among Veterans, which is highly prevalent and comorbid with psychopathology. However, even for evidence-based couple therapies, effectiveness is weaker compared to controlled studies, maybe because many Veteran couples drop out early and do not reach the "active" treatment stage after the 3-4 session assessment. In order to improve outcomes, it is critical to identify couples at high risk for early dropout, and understand whether couples may benefit from the assessment as an intervention. The current study examined (a) demographics, treatment delivery mode, relationship satisfaction, and psychological symptoms as predictors of dropout during and immediately following the assessment phase, and (b) changes in relationship satisfaction during assessment. 174 couples completed questionnaires during routine intake procedures. The main analyses focused on 140 male Veterans and their female civilian partners; 36.43% dropped out during the assessment phase and 24.74% of the remaining couples immediately following the first treatment session. More severe depressive symptoms in non-Veteran partners were associated with dropout during assessment. Relationship satisfaction improved significantly during the assessment phase for couples who did not drop out, with larger gains for non-Veteran partners. No demographics or treatment delivery mode were associated with dropout. Although more research is needed on engaging couples at risk for early dropout and maximizing early benefits, the findings suggest that clinicians should attend to the civilian partner's and Veteran's depressive symptoms at intake and consider the assessment part of active treatment. © 2017 Family Process Institute.

Early Education and Care, and Reconceptualizing Play. Advances in Early Education and Day Care.

ERIC Educational Resources Information Center

Reifel, Stuart, Ed.; Brown, Mac H., Ed.

Providing a forum for current thought about the field of early education and care, this book reviews efforts worldwide to educate young children. The book examines child care quality, presents a cultural feminist perspective on caregiving, discusses curricular issues, and considers the role of play in early childhood practice. The chapters are:…

Explaining Why Early-Maturing Girls Are More Exposed to Sexual Harassment in Early Adolescence

ERIC Educational Resources Information Center

Skoog, Therése; Bayram Özdemir, Sevgi

2016-01-01

In this study, we tested two competing explanations of the previously established link between early female puberty and sexual harassment in early adolescence. The sample included 680 seventh-grade Swedish girls (M[subscript age] = 13.40, SD = 0.53). Findings revealed that looking more sexually mature and being sexually active mediated the link…

Thermo spectral analysis (TSA) of living human skin by FT-IR -Development of a diagnostic method for the early detection of chronic diseases

NASA Astrophysics Data System (ADS)

Folberth, W.; Heim, G.

1985-12-01

A Fourier spectrometer was used in order to measure the spectral emissivity E(k) of human skin in the FIR region k=190-420 cm-1. Three studies on patient groups with defined chronic diseases have been performed: patients with untreated bronchial carcinoma, patients with rheumatic arthritis and patients with chronic renal insufficiency. In comparison with a symptomfree control group all patient groups show significant differences in E(k). As result of a discriminant analysis a separation of 95.7% between carcinoma patients and control persons is possible. The separation quotes between the other groups indicate that patients with malignant neoplasms can be discriminated from other chronically ill persons.

76 FR 51075 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Granting Approval to...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... options classes in which a CMM can initiate intraday quoting to the number of options classes in which it... proposes to limit the number of appointed options classes in which a CMM can initiate intraday quoting to...

Sophisticated digestive systems in early arthropods.

PubMed

Vannier, Jean; Liu, Jianni; Lerosey-Aubril, Rudy; Vinther, Jakob; Daley, Allison C

2014-05-02

Understanding the way in which animals diversified and radiated during their early evolutionary history remains one of the most captivating of scientific challenges. Integral to this is the 'Cambrian explosion', which records the rapid emergence of most animal phyla, and for which the triggering and accelerating factors, whether environmental or biological, are still unclear. Here we describe exceptionally well-preserved complex digestive organs in early arthropods from the early Cambrian of China and Greenland with functional similarities to certain modern crustaceans and trace these structures through the early evolutionary lineage of fossil arthropods. These digestive structures are assumed to have allowed for more efficient digestion and metabolism, promoting carnivory and macrophagy in early arthropods via predation or scavenging. This key innovation may have been of critical importance in the radiation and ecological success of Arthropoda, which has been the most diverse and abundant invertebrate phylum since the Cambrian.

Challenges facing early career academic cardiologists.

PubMed

Tong, Carl W; Ahmad, Tariq; Brittain, Evan L; Bunch, T Jared; Damp, Julie B; Dardas, Todd; Hijar, Amalea; Hill, Joseph A; Hilliard, Anthony A; Houser, Steven R; Jahangir, Eiman; Kates, Andrew M; Kim, Darlene; Lindman, Brian R; Ryan, John J; Rzeszut, Anne K; Sivaram, Chittur A; Valente, Anne Marie; Freeman, Andrew M

2014-06-03

Early career academic cardiologists currently face unprecedented challenges that threaten a highly valued career path. A team consisting of early career professionals and senior leadership members of American College of Cardiology completed this white paper to inform the cardiovascular medicine profession regarding the plight of early career cardiologists and to suggest possible solutions. This paper includes: 1) definition of categories of early career academic cardiologists; 2) general challenges to all categories and specific challenges to each category; 3) obstacles as identified by a survey of current early career members of the American College of Cardiology; 4) major reasons for the failure of physician-scientists to receive funding from National Institute of Health/National Heart Lung and Blood Institute career development grants; 5) potential solutions; and 6) a call to action with specific recommendations. Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Children’s early helping in action: Piagetian developmental theory and early prosocial behavior

PubMed Central

Hammond, Stuart I.

2014-01-01

After a brief overview of recent research on early helping, outlining some central problems, and issues, this paper examines children’s early helping through the lens of Piagetian moral and developmental theory, drawing on Piaget’s “Moral Judgment of the Child” (Piaget, 1932/1997), “Play, Dreams, and Imitation in Childhood” (Piaget, 1945/1951), and the “Grasp of Consciousness” (Piaget, 1976). Piaget refers to a level of moral development in action that precedes heteronomous and autonomous moral reasoning. This action level allows children to begin to interact with people and objects. In his later work, Piaget explores the gradual construction of understanding from this activity level. Taken together, these elements of Piagetian theory provide a promising conceptual framework for understanding the development of early helping. PMID:25101027

Morphogenesis of early stage melanoma

NASA Astrophysics Data System (ADS)

Chatelain, Clément; Amar, Martine Ben

2015-08-01

Melanoma early detection is possible by simple skin examination and can insure a high survival probability when successful. However it requires efficient methods for identifying malignant lesions from common moles. This paper provides an overview first of the biological and physical mechanisms controlling melanoma early evolution, and then of the clinical tools available today for detecting melanoma in vivo at an early stage. It highlights the lack of diagnosis methods rationally linking macroscopic observables to the microscopic properties of the tissue, which define the malignancy of the tumor. The possible inputs of multiscale models for improving these methods are shortly discussed.

Sequence stratigraphy, tectonics and hydrocarbon trap geometries of Middle Tertiary strata in the southern San Joaquin Basin, California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, S.; Hewlett, J.S.; Bazeley, W.J.M.

1996-01-01

Tectonic evolution of the southern San Joaquin basin exerted a fundamental control on Cenozoic sequence boundary development, reservoir, source and seal facies distribution, and hydrocarbon trap development. Spatial and temporal variations in Tertiary sequence architecture across the basin reflect differences in eastside versus westside basin-margin geometries and deformation histories. Deposition of Tertiary sequences initiated in a forearc basin setting, bounded on the east by a ramp-margin adjacent to the eroded Sierran arc complex and on the west by the imbricated accretionary wedge of the Coast Ranges thrust. The major stages of Cenozoic basin evolution are: (1) Episodic compressional folding andmore » thrusting associated with oblique convergence of the Farallon and North American plates (Late Cretaceous to Oligocene), (2) localized folding and onset of basin subsidence related to Pacific Plate reorganization, microplate formation and rotation (Oligocene to Early Miocene), (3) transtensional faulting, folding basin subsidence associated with initiation of the San Andreas transform and continued microplate rotation (Micocene to Pliocene), and (4) compressional folding, extensional and strike- slip faulting related to evolution of the Pacific-North American transform boundary (Plio- Pleistocene). Complex stratigraphic relationships within Eocene to Middle Miocene rocks provide examples of tectonic influences on sequence architecture. These include development of: (1) Tectonically enhanced sequence boundaries (Early Eocene base Domengine unconformity) and local mid-sequence angular unconformities, (2) westside-derived syntectonic [open quotes]lowstand[close quotes] systems (Yokut/Turitella Silt wedge and Leda Sand/Cymric/Salt Creek wedge), (3) regional seals associated with subsidence-related transgressions (Round Mountain Silt), and (4) combination traps formed by structural inversion of distal lowstand delta reservoirs (e.g. Coalinga East Extension field).« less

Sequence stratigraphy, tectonics and hydrocarbon trap geometries of Middle Tertiary strata in the southern San Joaquin Basin, California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, S.; Hewlett, J.S.; Bazeley, W.J.M.

1996-12-31

Tectonic evolution of the southern San Joaquin basin exerted a fundamental control on Cenozoic sequence boundary development, reservoir, source and seal facies distribution, and hydrocarbon trap development. Spatial and temporal variations in Tertiary sequence architecture across the basin reflect differences in eastside versus westside basin-margin geometries and deformation histories. Deposition of Tertiary sequences initiated in a forearc basin setting, bounded on the east by a ramp-margin adjacent to the eroded Sierran arc complex and on the west by the imbricated accretionary wedge of the Coast Ranges thrust. The major stages of Cenozoic basin evolution are: (1) Episodic compressional folding andmore » thrusting associated with oblique convergence of the Farallon and North American plates (Late Cretaceous to Oligocene), (2) localized folding and onset of basin subsidence related to Pacific Plate reorganization, microplate formation and rotation (Oligocene to Early Miocene), (3) transtensional faulting, folding basin subsidence associated with initiation of the San Andreas transform and continued microplate rotation (Micocene to Pliocene), and (4) compressional folding, extensional and strike- slip faulting related to evolution of the Pacific-North American transform boundary (Plio- Pleistocene). Complex stratigraphic relationships within Eocene to Middle Miocene rocks provide examples of tectonic influences on sequence architecture. These include development of: (1) Tectonically enhanced sequence boundaries (Early Eocene base Domengine unconformity) and local mid-sequence angular unconformities, (2) westside-derived syntectonic {open_quotes}lowstand{close_quotes} systems (Yokut/Turitella Silt wedge and Leda Sand/Cymric/Salt Creek wedge), (3) regional seals associated with subsidence-related transgressions (Round Mountain Silt), and (4) combination traps formed by structural inversion of distal lowstand delta reservoirs (e.g. Coalinga East Extension field).« less

Gas play opportunities in deeper Jurassic sequences of the Neuquen basin embayment, Argentina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fernandez-Seveso, F.; Figueroa, D.E.; Rodriguez, H.

1996-08-01

We have defined new gas plays at around 4000 m depth near the giant Loma La Lata gas field. The plays, in lower Jurassic sandstones, were developed using a different approach in stratigraphic signatures as well as deformation styles. Two initial rifting stages led to the Triassic-Early Liassic volcanoclastic deposition (Precuyo s.l.) into a suite of discrete half-grabens. The late rifting stage amalgamated the Precuyo depocenters into notably extended subsiding half-grabens where the Pliensbachian-Toarcian deposits were accommodated. This lower Cuyo sequence-set (LC) consists of basinal marine shales (Molles Formation) and a progradational stacking of slope and shelf sandstones (Lajas Formation),more » bearing a kerogen type III-II within the gas window with TOC values range 2-6%. The LC top matches with a conspicuous regional unconformity related to the thermo-mechanic subsidence. The overlying Bajocian-early Callovian upper Cuyo sequence set exhibits outer shelf argillaceous sediments at the base. The identified plays are related to two deformation mechanisms: mud diapirism and tectonic inversion. The thick, rapidly deposited LC sandstones triggered the ductile flow of the underlying, overpressured shales. Soon after, the tectonic inversion of the Precuyo half-grabens produced a series of aligned anticlines parallel to Huincul Arch. Scattered incipient diapirism toward the embayment resulted in dome-like structures. Sandstones with gas shows could act as {open_quotes}tight gas reservoirs.{close_quotes} However, increased permeability through natural fracturing in the structures would increase their viability. The estimated resources of several TCF in untested closures and the industry infrastructure make these plays particularly attractive for gas exploration.« less

Characteristics and origin of Earth-mounds on the Eastern Snake River Plain, Idaho

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tullis, J.A.

1995-09-01

Earth-mounds are common features on the Eastern Snake River Plain, Idaho. The mounds are typically round or oval in plan view, <0.5 m in height, and from 8 to 14 m in diameter. They are found on flat and sloped surfaces, and appear less frequently in lowland areas. The mounds have formed on deposits of multiple sedimentary environments. Those studied included alluvial gravel terraces along the Big Lost River (late Pleistocene/early Holocene age), alluvial fan segments on the flanks of the Lost River Range (Bull Lake and Pinedale age equivalents), and loess/slopewash sediments overlying basalt flows. Backhoe trenches were dugmore » to allow characterization of stratigraphy and soil development. Each mound has features unique to the depositional and pedogenic history of the site; however, there are common elements to all mounds that are linked to the history of mound formation. Each mound has a {open_quotes}floor{close_quotes} of a sediment or basement rock of significantly different hydraulic conductivity than the overlying sediment. These paleosurfaces are overlain by finer-grained sediments, typically loess or flood-overbank deposits. Mounds formed in environments where a sufficient thickness of fine-grained sediment held pore water in a system open to the migration to a freezing front. Heaving of the sediment occurred by the growth of ice lenses. Mound formation occurred at the end of the Late Pleistocene or early in the Holocene, and was followed by pedogenesis. Soils in the mounds were subsequently altered by bioturbation, buried by eolian deposition, and eroded by slopewash runoff. These secondary processes played a significant role in maintaining or increasing the mound/intermound relief.« less

Analysis of Early Military Attrition Behavior.

DTIC Science & Technology

1984-06-01

military separation. Although hizh school graduation status is the primary single factor affecting attrition, age and previous employment stability...assignment like individual suitability and satisfaction do not significantly influence early attrition; the early attrition rate of nonhigh- school ...a recruit with a single previous employer. I I V IS BLANK vi * Various indicators of military job match had no significant impact on early attrition

[Early mobilization. Competencies, responsibilities, milestones].

PubMed

Nydahl, P; Dewes, M; Dubb, R; Filipovic, S; Hermes, C; Jüttner, F; Kaltwasser, A; Klarmann, S; Klas, K; Mende, H; Rothaug, O; Schuchhardt, D

2016-03-01

Early mobilization is an evident, interprofessional concept to improve the outcome of intensive care patients. It reduces psychocognitive deficits and delirium and attenuates a general deconditioning, including atrophy of the respiratory pump and skeletal muscles. In this regard the interdisciplinary approach of early mobilization, taking into account different levels of mobilization, appears to be beneficial. The purpose of this study was to explore opinions on collaboration and tasks between different professional groups. During the 25th Bremen Conference on Intensive Medicine and Nursing on 20 February 2015, a questionnaire survey was carried out among the 120 participants of the German Early Mobilization Network meeting. In all, 102 questionnaires were analyzed. Most participants reported on the interdisciplinarity of the approach, but none of the tasks and responsibilities concerning early mobilization can be assigned to a single professional group. The practical implementation of mobilizing orally intubated patients may require two registered nurses as well as a physical therapist. Implementation in daily practice seems to be heterogeneous. There is no consensus regarding collaboration, competencies, and responsibilities with respect to early mobilization of intensive care patients. The approach to date has been characterized by a lack of interprofessional communication, which may lead to an inefficient use of the broad and varied base of knowledge and experienceof the different professions.

Telomere lengthening early in development.

PubMed

Liu, Lin; Bailey, Susan M; Okuka, Maja; Muñoz, Purificación; Li, Chao; Zhou, Lingjun; Wu, Chao; Czerwiec, Eva; Sandler, Laurel; Seyfang, Andreas; Blasco, Maria A; Keefe, David L

2007-12-01

Stem cells and cancer cells maintain telomere length mostly through telomerase. Telomerase activity is high in male germ line and stem cells, but is low or absent in mature oocytes and cleavage stage embryos, and then high again in blastocysts. How early embryos reset telomere length remains poorly understood. Here, we show that oocytes actually have shorter telomeres than somatic cells, but their telomeres lengthen remarkably during early cleavage development. Moreover, parthenogenetically activated oocytes also lengthen their telomeres, thus the capacity to elongate telomeres must reside within oocytes themselves. Notably, telomeres also elongate in the early cleavage embryos of telomerase-null mice, demonstrating that telomerase is unlikely to be responsible for the abrupt lengthening of telomeres in these cells. Coincident with telomere lengthening, extensive telomere sister-chromatid exchange (T-SCE) and colocalization of the DNA recombination proteins Rad50 and TRF1 were observed in early cleavage embryos. Both T-SCE and DNA recombination proteins decrease in blastocyst stage embryos, whereas telomerase activity increases and telomeres elongate only slowly. We suggest that telomeres lengthen during the early cleavage cycles following fertilization through a recombination-based mechanism, and that from the blastocyst stage onwards, telomerase only maintains the telomere length established by this alternative mechanism.

Early Identification of Autism

PubMed Central

Webb, Sara Jane; Jones, Emily J.H.

2016-01-01

In the first year of life, infants who later go on to develop autistic spectrum disorders (ASD) may exhibit subtle disruptions in social interest and attention, communication, temperament, and head circumference growth that occur prior to the onset of clinical symptoms. These disruptions may reflect the early course of ASD development and may also contribute to the later development of clinical symptoms through alterations in the child’s experience of his or her environment. By age 2, developmental precursors of autism symptoms can be used to diagnose children reliably, and by age 3, the diagnosis is thought to be relatively stable. The downward extension of the autism diagnosis poses important questions for therapists in designing interventions that are applicable for infants who demonstrate early risk factors. We review current knowledge of the early signs of ASD in the infancy period (0–12 months) and the manifestation of symptoms in toddlerhood (12– 36 months), noting the importance of considering the variability in onset and trajectory of ASD. Finally, we consider the implications of this emerging research for those who work or interact with young children, including the importance of early monitoring and the development and evaluation of age-appropriate interventions. PMID:28090148

Fine localization of the locus for autosomal dominant retinitis pigmentosa on chromosome 17p

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goliath, R.; Janssens, P.; Beighton, P.

1995-10-01

The term {open_quotes}retintis pigmentosa{close_quotes} (RP) refers to a group of inherited retinal degenerative disorders. Clinical manifestations include night-blindness, with variable age of onset, followed by constriction of the visual field that may progress to total loss of sight in later life. Previous studies have shown that RP is caused by mutations within different genes and may be inherited as an X-linked recessive (XLRRP), autosomal recessive (ARRP), or autosomal dominant (ADRP) trait. The AD form of this group of conditions has been found to be caused by mutations within the rhodopsin gene in some families and the peripherin/RDS gene in others.more » In addition, some ADRP families have been found to be linked to anonymous markers on 8cen, 7p, 7q,19q, and, more recently, 17p. The ADRP gene locus on the short arm of chromosome 17 was identified in a large South African family (ADRP-SA) of British origin. The phenotypic expression of the disorder, which has been described elsewhere is consistent in the pedigree with an early onset of disease symptoms. In all affected subjects in the family, onset of symptoms commenced before the age of 10 years. 16 refs., 3 figs., 1 tab.« less

Physical mapping of the torsion dystonia region of human chromosome 9q34

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ozelius, L.J.; Hewett, J.; Shalish, C.

1994-09-01

Torsion dystonia is a syndrome characterized by loss of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. The DYT1 gene is responsible for a subtype of torsion dystonia in which onset of symptoms tends to occur in a limb at an early age (mean 13 years) and to progress to a generalized state. Expression of the disease gene follows an autosomal dominant mode of inheritance with reduced penetrance. We initially mapped this gene to human chromosome 9q34 and have now defined its location to a < 1 cM region near the ASS locus based on historic recombination eventsmore » around a founder mutation in the Ashkenazic Jewish population. Using the CEPH YAC library and a chromosome 9 flow-sorted YAC library, we have generated a YAC contig spanning about 500 kb of this region. These YACs are being used to identify cosmids by direct hybridization to chromosome 9-specific cosmid libraries. Cosmids are being aligned by restriction digest patterns and by hybridization with oligonucleotide repeat probes. In addition, the cosmids are being {open_quotes}trapped{close_quotes} by exon amplification and these exons used to screen cDNA libraries. Thus far we have identified several candidate transcripts in this region.« less

Early Intervention in Psychosis

PubMed Central

McGorry, Patrick D.

2015-01-01

Abstract Early intervention for potentially serious disorder is a fundamental feature of healthcare across the spectrum of physical illness. It has been a major factor in the reductions in morbidity and mortality that have been achieved in some of the non-communicable diseases, notably cancer and cardiovascular disease. Over the past two decades, an international collaborative effort has been mounted to build the evidence and the capacity for early intervention in the psychotic disorders, notably schizophrenia, where for so long deep pessimism had reigned. The origins and rapid development of early intervention in psychosis are described from a personal and Australian perspective. This uniquely evidence-informed, evidence-building and cost-effective reform provides a blueprint and launch pad to radically change the wider landscape of mental health care and dissolve many of the barriers that have constrained progress for so long. PMID:25919380

Orphan radon daughters at Denver Radium site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holub, R.F.; Droullard, R.F.; Davis, T.H.

During 18 mo of sampling airborne radioactively at a National Priority List ({open_quotes}Superfund{close_quotes}) site in metroPOlitan Denver, Bureau of mines personnel discovered radon daughters that are not supported by the parent radon gas. We refer to them as {open_quotes}orphan{close_quotes} daughters because the parent, radon, is not present in sufficient concentration to support the measured daughter products. Measurements of the {open_quotes}orphan{close_quotes} daughters were made continuously, using the Bureau-developed radon and working-level (radon-daughter) monitors. The data showed high equilibrium ratios, ranging from 0.7 to 3.5, for long periods of time. Repeated, high-volume, 15-min grab samples were made, using the modified Tsivoglou method,more » to measure radon daughters, to which thoron daughters contributed 26 {+-} 12%. On average 28 {+-} 6% of the particulate activity was contributed by thoron daughters. Most samples were mixtures in which the {sup 218}Po concentration was lower than that of {sup 214}Pb and {sup 214}Bi, in agreement with the high-equilibrium factors obtained from the continuous sampling data. In view of the short half-life of radon progeny, we conclude that the source of the orphan daughters is not far from the Superfund sites. The mechanism of this phenomenon is not understood at this time, but we will discuss its possible significance in evaluating population doses.« less

An analysis of the equivalent dose calculation for the remainder tissues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zankl, M.; Drexler, G.

1995-09-01

In the 1990 Recommendations of the International Commission on Radiological Protection, the risk-weighted quantity {open_quotes}effective dose equivalent{close_quotes} was replaced by a similar quantity, {open_quotes}effective dose.{close_quotes} Among other alterations, the selection of the organs and tissues contributing to the risk-weighted quantity and their respective weighting factors were changed, including a modified definition of the so-called {open_quotes}remainder.{close_quotes} Close consideration of this latter definition shows that is causes certain ambiguities are unexpected effects which are dealt with in the following. For several geometries of external photon irradiation, the numerical differences of two possible methods of evaluating the remainder dose from the doses tomore » ten single organs, namely as arithmetic mean or as mass weighted average, are assessed. It is shown that deviation from these averaging procedures, as prescribed for these cases where a remainder organ receives a higher dose than an organ with a specified weighting factor, cause discontinuities in the energy dependence of the remainder dose and, consequently, also non-additivity of this quantity. These problems are discussed, and it is shown that, although the numerical consequences for the calculation of the effective dose are small, this unsatisfactory situation needs clarification. One approach might be to abolish some of the ICRP guidance relating to the appropriate tissue weighting factors for the remainder tissues and organs and to make other guidance more precise. 14 refs., 12 figs., 2 tabs.« less

Texas lignite mining: Groundwater and slope stability control in the nineties and beyond

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawrence J.

As lignite mining in Texas approaches and exceeds depths of 200 feet below ground level, rising costs demand that innovative mining approaches be used in order to maintain the economic viability of lignite mining. Groundwater and slope stability problems multiply at these depths, resulting in increasing focus on how to control these costs. Dewatering costs are consistently rising for the lignite industry, as deeper mining encounters more and larger saturated sand bodies. These sands require dewatering in order to improve slope stability. Planning and analysis become more important as the number of wells grows beyond what can be managed withmore » a simple {open_quotes}cookie-cutter{close_quotes} approach. Slope stability plays an increasing role in mining concerns as deeper lignite is recovered. Slope stability causes several problems, including loss of lignite, increased rehandle, and hazards to personnel and equipment. Traditional lignite mine planning involved a fairly {open_quotes}generic{close_quotes} pit design with one design highwall angle, one design spoil angle, and little geotechnical evaluation of the deposit. This {open_quotes}one mine-one design{close_quotes} approach, while cost-effective in the past, is now being replaced by a more critical analysis of the design requirements of each area. Geotechnical evaluation plays an increasing role in the planning and operational aspects of lignite mining. Laboratory core sample test results can be used for slope stability modeling, in order to obtain more accurate design and operational information.« less

Pt-black catalysts sintered at different temperatures: Surface analysis and activity in reactions of n-hexane

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paal, Z.; Xu, X.L.; Paal-Lukacs, J.

Pt-black catalysts sintered at 473 and 633 K ({open_quotes}Pt-473{close_quotes} and {open_quotes}Pt-633{close_quotes}), respectively, have been characterized by X-ray diffraction and analyzed by XPS, UPS, and AES after carrying out n-hexane reactions. The analysis has been repeated after O{sub 2}-H{sub 2} regeneration in the preparation chamber of the UHV apparatus. The surface of the blacks contains some carbon and oxygen impurities even after regeneration. Both Pt-473 and Pt-633 show high Pt 4f line intensity. Decomposition of the C 1s line reveals a higher amount of oxidized carbon polymers on Pt-633. This sample is free from lattice strain. The likely higher abundance ofmore » exposed hexagonal symmetry faces, namely the (111) plane and analogous stepped and kinked structures, may be one of the reasons why fragmentation and aromatization are favored on Pt-633, as opposed to the higher selectivity of isomerization and C{sub 5}-cyclization on Pt-473. The higher amount of oxidized carbonaceous polymer overlayer (serving as {open_quotes}hydrogen catcher{close_quotes}) on Pt-633 as well as the less-retained hydrogen by its crystallites without lattice strain may also contribute to the different selectivity and hydrogen pressure response of the n-hexane reaction over the two samples. Product ratios are suggested as an additional diagnostic tool for characterizing the hydrogen availability on the catalysts. 59 refs., 9 figs., 5 tabs.« less

Evidence for a chromosome 22q susceptibility locus for some schizophrenics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pulver, A.E.; Wolyniec, P.; Nestadt, G.

Recent reports from linkage studies suggests that in some families there may be a gene associated with schizophrenia on chromosome 22q. Given the probable heterogeneity of schizophrenia, further exploration of this region was undertaken. The region was examined for candidate genes and diseases reported to have some psychiatric manifestations. Studies were initiated to examine the the potential phenotypic and molecular similarity between schizophrenia and velo-cardio-facial syndrome (VCFS), a syndrome associated with an interstitial deletion of 22q11.2. Phenotypic expression: (1) psychiatric evaluations of VCFS patients and their relatives found a high rate of DSM III-R schizophrenia in the patients and ofmore » psychotic illness in their 2nd and 3rd degree relatives. (2) 160 schizophrenic patients from the Maryland Epidemiology Sample (MES) were evaluated for the presence of typical facies seen in VCFS. Rating a 5-point scale, {open_quotes}5{close_quotes} being most likely, 15 (9.4%) were rated {open_quotes}5{close_quotes} and 27 (16.9%) were rated {open_quotes}4{close_quotes} for the VCFS-like facial features. Molecular characteristics: fluorescent in situ hybridization methods (FISH) identified 3 schizophrenics among 60 in the MES with the microdeletion of probe sc11.lab commonly deleted in VCFS subjects. This work provides a model for the mapping of complex phenotypes such schizophrenia using both genetic and epidemiological methods.« less

Early intervention for psychosis

PubMed Central

Marshall, Max; Rathbone, John

2014-01-01

Background Proponents of early intervention have argued that outcomes might be improved if more therapeutic efforts were focused on the early stages of schizophrenia or on people with prodromal symptoms. Early intervention in schizophrenia has two elements that are distinct from standard care: early detection, and phase-specific treatment (phase-specific treatment is a psychological, social or physical treatment developed, or modified, specifically for use with people at an early stage of the illness). Early detection and phase-specific treatment may both be offered as supplements to standard care, or may be provided through a specialised early intervention team. Early intervention is now well established as a therapeutic approach in America, Europe and Australasia. Objectives To evaluate the effects of: (a) early detection; (b) phase-specific treatments; and (c) specialised early intervention teams in the treatment of people with prodromal symptoms or first-episode psychosis. Search methods We searched the Cochrane Schizophrenia Group Trials Register (March 2009), inspected reference lists of all identified trials and reviews and contacted experts in the field. Selection criteria We included all randomised controlled trials (RCTs) designed to prevent progression to psychosis in people showing prodromal symptoms, or to improve outcome for people with first-episode psychosis. Eligible interventions, alone and in combination, included: early detection, phase-specific treatments, and care from specialised early intervention teams. We accepted cluster-randomised trials but excluded non-randomised trials. Data collection and analysis We reliably selected studies, quality rated them and extracted data. For dichotomous data, we estimated relative risks (RR), with the 95% confidence intervals (CI). Where possible, we calculated the number needed to treat/harm statistic (NNT/H) and used intention-to-treat analysis (ITT). Main results Studies were diverse, mostly small

Early identification systems for emerging foodborne hazards.

PubMed

Marvin, H J P; Kleter, G A; Prandini, A; Dekkers, S; Bolton, D J

2009-05-01

This paper provides a non-exhausting overview of early warning systems for emerging foodborne hazards that are operating in the various places in the world. Special attention is given to endpoint-focussed early warning systems (i.e. ECDC, ISIS and GPHIN) and hazard-focussed early warning systems (i.e. FVO, RASFF and OIE) and their merit to successfully identify a food safety problem in an early stage is discussed. Besides these early warning systems which are based on monitoring of either disease symptoms or hazards, also early warning systems and/or activities that intend to predict the occurrence of a food safety hazard in its very beginning of development or before that are described. Examples are trend analysis, horizon scanning, early warning systems for mycotoxins in maize and/or wheat and information exchange networks (e.g. OIE and GIEWS). Furthermore, recent initiatives that aim to develop predictive early warning systems based on the holistic principle are discussed. The assumption of the researchers applying this principle is that developments outside the food production chain that are either directly or indirectly related to the development of a particular food safety hazard may also provide valuable information to predict the development of this hazard.

Biochemical Processes | Bioenergy | NREL

Science.gov Websites

;, red is labeled "Family 5", blue is labeled "Family 6", green is labeled &quot ;Family 7", purple is labeled "Family 12", and yellow is labeled "Family 45&quot

Effects of Platform Design on the Customer Experience in an Online Solar PV Marketplace

DOE Office of Scientific and Technical Information (OSTI.GOV)

OShaughnessy, Eric J.; Margolis, Robert M.; Leibowicz, Benjamin

We analyze a unique dataset of residential solar PV quotes offered in an online marketplace to understand how platform design changes affect customer outcomes. Three of the four design changes are associated with statistically significant and robust reductions in offer prices, though none of the policies were designed explicitly to reduce prices. The results suggest that even small changes in how prospective solar PV customers interact with installers can affect customer outcomes such as prices. Specifically, the four changes we evaluate are: 1) a customer map that shows potential new EnergySage registrants the locations of nearby customers; 2) a quotemore » cap that precludes more than seven installers from bidding on any one customer; 3) a price guidance feature that informs installers about competitive prices in the customer's market before they submit quotes; and 4) no pre-quote messaging to prohibit installers from contacting customers prior to offering quotes. We calculate descriptive statistics to investigate whether each design change accomplished its specific objectives. Then, we econometrically evaluate the impacts of the design changes on PV quote prices and purchase prices using a regression discontinuity approach.« less

75 FR 20830 - Early Learning

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

... meetings and written submissions, is seeking input from State agencies responsible for early learning and... intervention service providers and other providers of services to young children), students, technical... receive all written submissions of comments on the four early learning topics on or before 5 p.m...

Enhanced influence of early-spring tropical Indian Ocean SST on the following early-summer precipitation over Northeast China

NASA Astrophysics Data System (ADS)

Han, Tingting; He, Shengping; Wang, Huijun; Hao, Xin

2017-04-01

The relationship between the tropical Indian Ocean (TIO) and East Asian summer monsoon/precipitation has been documented in many studies. However, the precursor signals of summer precipitation in the TIO sea surface temperature (SST), which is important for climate prediction, have drawn little attention. This study identified a strong relationship between early-spring TIO SST and subsequent early-summer precipitation in Northeast China (NEC) since the late 1980s. For 1961-1986, the correlations between early-spring TIO SST and early-summer NEC precipitation were statistically insignificant; for 1989-2014, they were positively significant. Since the late 1980s, the early-spring positive TIO SST anomaly was generally followed by a significant anomalous anticyclone over Japan; that facilitated anomalous southerly winds over NEC, conveying more moisture from the North Pacific. Further analysis indicated that an early TIO SST anomaly showed robust persistence into early summer. However, the early-summer TIO SST anomaly displayed a more significant influence on simultaneous atmospheric circulation and further affected NEC precipitation since the late 1980s. In 1989-2014, the early-summer Hadley and Ferrell cell anomalies associated with simultaneous TIO SST anomaly were much more significant and extended further north to mid-latitudes, which provided a dynamic foundation for the TIO-mid-latitude connection. Correspondingly, the TIO SST anomaly could lead to significant divergence anomalies over the Mediterranean. The advections of vorticity by the divergent component of the flow effectively acted as a Rossby wave source. Thus, an apparent Rossby wave originated from the Mediterranean and propagated east to East Asia; that further influenced the NEC precipitation through modulation to the atmospheric circulation (e.g., surface wind, moisture, vertical motion).

Early Diagnosis of Breast Cancer.

PubMed

Wang, Lulu

2017-07-05

Early-stage cancer detection could reduce breast cancer death rates significantly in the long-term. The most critical point for best prognosis is to identify early-stage cancer cells. Investigators have studied many breast diagnostic approaches, including mammography, magnetic resonance imaging, ultrasound, computerized tomography, positron emission tomography and biopsy. However, these techniques have some limitations such as being expensive, time consuming and not suitable for young women. Developing a high-sensitive and rapid early-stage breast cancer diagnostic method is urgent. In recent years, investigators have paid their attention in the development of biosensors to detect breast cancer using different biomarkers. Apart from biosensors and biomarkers, microwave imaging techniques have also been intensely studied as a promising diagnostic tool for rapid and cost-effective early-stage breast cancer detection. This paper aims to provide an overview on recent important achievements in breast screening methods (particularly on microwave imaging) and breast biomarkers along with biosensors for rapidly diagnosing breast cancer.

Lighting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Audin, L.

1994-12-31

EPAct covers a vast territory beyond lighting and, like all legislation, also contains numerous {open_quotes}favors,{close_quotes} compromises, and even some sleight-of-hand. Tucked away under Title XIX, for example, is an increase from 20% to 28% tax on gambling winnings, effective January 1, 1993 - apparently as a way to help pay for new spending listed elsewhere in the bill. Overall, it is a landmark piece of legislation, about a decade overdue. It remains to be seen how the Federal Government will enforce upgrading of state (or even their own) energy codes. There is no mention of funding for {open_quotes}energy police{close_quotes} inmore » EPAct. Merely creating such a national standard, however, provides a target for those who sincerely wish to create an energy-efficient future.« less

Synchrotron x-ray diffraction studies of the structural properties of electrode materials in operating battery cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thurston, T.R.; Jisrawi, N.M.; Mukerjee, S.

Hard x rays from a synchrotron source were utilized in diffraction experiments which probed the bulk of electrode materials while they were operating {ital in} {ital situ} in battery cells. Two technologically relevant electrode materials were examined; an {ital AB}{sub 2}-type anode in a nickel{endash}metal{endash}hydride cell and a LiMn{sub 2}O{sub 4} cathode in a Li-ion {open_quote}{open_quote}rocking chair{close_quote}{close_quote} cell. Structural features such as lattice expansions and contractions, phase transitions, and the formation of multiple phases were easily observed as either hydrogen or lithium was electrochemically intercalated in and out of the electrode materials. The relevance of this technique for future studiesmore » of battery electrode materials is discussed. {copyright} {ital 1996 American Institute of Physics.}« less

IAEA international studies on irradiation embrittlement of reactor pressure vessel steels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brumovsky, M.; Steele, L.E.

1997-02-01

In last 25 years, three phases a Co-operative Research Programme on Irradiation Embrittlement of Reactor Pressure Vessel Steels has been organized by the International Atomic Energy Agency. This programme started with eight countries in 1971 and finally 16 countries took part in phase III of the Programme in 1983. Several main efforts were put into preparation of the programme, but the principal task was concentrated on an international comparison of radiation damage characterization by different laboratories for steels of {open_quotes}old{close_quotes} (with high impurity contents) and {open_quotes}advanced{close_quotes} (with low impurity contents) types as well as on development of small scale fracturemore » mechanics procedures applicable to reactor pressure vessel surveillance programmes. This year, a new programme has been opened, concentrated mostly on small scale fracture mechanics testing.« less

How to manage without being a manager

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sweeney, M.A.

1997-06-01

In the author`s current position at Sandia National Laboratories within the Pulsed Power Sciences Center, much of the author`s time is spent in composing short (one page) technical reports and long (> 20 page) technical contracts and program plans for transmission to the Department of Energy and to upper management and also in reviewing long technical documents for accuracy. A major requirement of these efforts is to complete them on a timely basis, often within a few hours or a few days. In this talk, the author reveals some communication {open_quotes}secrets{close_quotes} that have been learned. The idea behind these twelvemore » {open_quotes}secrets{close_quotes} is to get the answers you, as a nonmanager, need quickly from a manager without creating stress either on your part or the manager`s part.« less

De novo tandem duplication of chromosome segement 22q11-q12: Clinical, cytogenetic, and molecular characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lindsay, E.A.; Shaffer, L.G.; Carrozzo, R.

We report on a case of duplication of the segment 22q11-q12 due to a de novo duplication. Molecular cytogenetics studies demonstrated this to be a tandem duplication, flanked proximally by the marker D22Z4, a centromeric alpha satellite DNA repeat, and distally by D22S260, an anonymous DNA marker proximal to the Ewing sarcoma breakpoint. The segment includes the regions responsible for the {open_quotes}cat-eye{close_quotes}, Di George, and velo-cardio-facial syndromes and extends distal to the breakpoint cluster region (BCR). The clinical picture is dominated by the cardiac defects and includes findings reminiscent of {open_quotes}cat-eye{close_quotes} syndrome. These findings reinforce the hypothesis that the proximalmore » 22q region contains dosage-sensitive genes involved in development. 20 refs., 3 figs.« less

77 FR 16551 - Early Retiree Reinsurance Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

...] Early Retiree Reinsurance Program AGENCY: Centers for Medicare & Medicaid Services (CMS), HHS. ACTION: Notice. SUMMARY: This notice establishes a timeframe by which plan sponsors participating in the Early... Early Retiree Reinsurance Program (ERRP) which provides reimbursement to eligible sponsors of employment...

Early Rockets

NASA Image and Video Library

2004-04-15

In the 19th Century, experiments in America, Europe, and elsewhere attempted to build postal rockets to deliver mail from one location to another. The idea was more novel than successful. Many stamps used in these early postal rockets have become collector's items.

40 CFR 63.78 - Early reduction demonstration evaluation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Early reduction demonstration... Regulations Governing Compliance Extensions for Early Reductions of Hazardous Air Pollutants § 63.78 Early reduction demonstration evaluation. (a) The permitting authority will evaluate an early reduction...

40 CFR 63.78 - Early reduction demonstration evaluation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 9 2011-07-01 2011-07-01 false Early reduction demonstration... Regulations Governing Compliance Extensions for Early Reductions of Hazardous Air Pollutants § 63.78 Early reduction demonstration evaluation. (a) The permitting authority will evaluate an early reduction...

Erratum: Letter to the Editor: Exclusion of primary congenital glaucoma (buphthalmos) from two candidate regions of chromosome arm 6p and chromosome 11

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This {open_quotes}Letter to the Editor{close_quotes} is the reprint of a corrected table from a previous paper about the exclusion of primary congenital glaucoma from two candidate regions of chromosome arm 6p and chromosome 11.

Early Childhood Education in Taiwan.

ERIC Educational Resources Information Center

Barclay, Lisa K.

1989-01-01

Describes early childhood education in Taiwan, focusing on living patterns and child care arrangements, the position of the individual within the family and community, and the application of cultural norms to early childhood education. Compares the behavior of Chinese preschool children to that of American preschool children. (RJC)

Early caregiving and physiological stress responses.

PubMed

Luecken, Linda J; Lemery, Kathryn S

2004-05-01

Inadequate early caregiving has been associated with risks of stress-related psychological and physical illness over the life span. Dysregulated physiological stress responses may represent a mechanism linking early caregiving to health outcomes. This paper reviews evidence linking early caregiving to physiological responses that can increase vulnerability to stress-related illness. A number of high-risk family characteristics, including high conflict, divorce, abuse, and parental psychopathology, are considered in the development of stress vulnerability. Three theoretical pathways linking caregiving to physiological stress responses are outlined: genetic, psychosocial, and cognitive-affective. Exciting preliminary evidence suggests that early caregiving can impact long-term physiological stress responses. Directions for future research in this area are suggested.

Race to the Top--Early Learning Challenge: An Analysis of Impact on IDEIA, Part C Early Intervention Programs

ERIC Educational Resources Information Center

Bohjanen, Sharon L.

2016-01-01

Infants and toddlers who live in poverty are more likely to experience developmental delays or disabilities and less likely to access early intervention (EI) services. The federal initiative Race to the Top--Early Learning Challenge (RTT-ELC) was designed to increase access to high quality early learning programs for children at risk for…

Building Community Systems for Young Children: Early Childhood Education. Building State Early Childhood Comprehensive Systems Series, Number 11

ERIC Educational Resources Information Center

Bassok, Daphna; Stipek, Deborah; Inkelas, Moira; Kuo, Alice

2005-01-01

This report examines the importance and funding sources of early child care and education (ECE), and the ways in which the State Early Childhood Comprehensive Systems (SECCS) Initiative improves early childhood outcomes. Section I presents what is known about the importance of ECE, quality and access. Section II describes the current funding…

Examining the Challenges Early Childhood Teacher Candidates Face in Figuring Their Roles as Early Educators

ERIC Educational Resources Information Center

Brown, Christopher P.; Feger, Beth Smith

2010-01-01

Federal, state, and local policy makers' high-stakes standards-based accountability reforms are transforming the early childhood teacher education process. These reforms affect how early education teacher candidates figure their role as teachers. By employing Holland, Lachicotte, Skinner, and Cain's conception of figured worlds to analyze the…

Early Detection of Sporadic Pancreatic Cancer

PubMed Central

Chari, Suresh T.; Kelly, Kimberly; Hollingsworth, Michael A.; Thayer, Sarah P.; Ahlquist, David A.; Andersen, Dana K.; Batra, Surinder K.; Brentnall, Teresa A.; Canto, Marcia; Cleeter, Deborah F.; Firpo, Matthew A.; Gambhir, Sanjiv Sam; Go, Vay Liang W.; Hines, O. Joe; Kenner, Barbara J.; Klimstra, David S.; Lerch, Markus M.; Levy, Michael J.; Maitra, Anirban; Mulvihill, Sean J.; Petersen, Gloria M.; Rhim, Andrew D.; Simeone, Diane M.; Srivastava, Sudhir; Tanaka, Masao; Vinik, Aaron I.; Wong, David

2015-01-01

Abstract Pancreatic cancer (PC) is estimated to become the second leading cause of cancer death in the United States by 2020. Early detection is the key to improving survival in PC. Addressing this urgent need, the Kenner Family Research Fund conducted the inaugural Early Detection of Sporadic Pancreatic Cancer Summit Conference in 2014 in conjunction with the 45th Anniversary Meeting of the American Pancreatic Association and Japan Pancreas Society. This seminal convening of international representatives from science, practice, and clinical research was designed to facilitate challenging interdisciplinary conversations to generate innovative ideas leading to the creation of a defined collaborative strategic pathway for the future of the field. An in-depth summary of current efforts in the field, analysis of gaps in specific areas of expertise, and challenges that exist in early detection is presented within distinct areas of inquiry: Case for Early Detection: Definitions, Detection, Survival, and Challenges; Biomarkers for Early Detection; Imaging; and Collaborative Studies. In addition, an overview of efforts in familial PC is presented in an addendum to this article. It is clear from the summit deliberations that only strategically designed collaboration among investigators, institutions, and funders will lead to significant progress in early detection of sporadic PC. PMID:25931254

Gaia Data Release 1. Validation of the photometry

NASA Astrophysics Data System (ADS)

Evans, D. W.; Riello, M.; De Angeli, F.; Busso, G.; van Leeuwen, F.; Jordi, C.; Fabricius, C.; Brown, A. G. A.; Carrasco, J. M.; Voss, H.; Weiler, M.; Montegriffo, P.; Cacciari, C.; Burgess, P.; Osborne, P.

2017-04-01

Aims: The photometric validation of the Gaia DR1 release of the ESA Gaia mission is described and the quality of the data shown. Methods: This is carried out via an internal analysis of the photometry using the most constant sources. Comparisons with external photometric catalogues are also made, but are limited by the accuracies and systematics present in these catalogues. An analysis of the quoted errors is also described. Investigations of the calibration coefficients reveal some of the systematic effects that affect the fluxes. Results: The analysis of the constant sources shows that the early-stage photometric calibrations can reach an accuracy as low as 3 mmag.

Text-Bullying among Early Adolescents

ERIC Educational Resources Information Center

Raskauskas, Juliana

2007-01-01

Increased availability of cell-phones has provided new avenues through which adolescents can bully their peers. Text-bullying is an emerging form of bullying which may threaten the emotional well-being of early adolescents. In this study 565 early adolescents (10-13 years old) completed questionnaires regarding their experiences with bullying…

Wyoming Early Childhood Readiness Standards.

ERIC Educational Resources Information Center

Wyoming State Dept. of Education, Cheyenne.

Because children entering kindergarten come with a variety of preschool and home experiences, and accordingly, with varying levels of school readiness, the Wyoming Early Childhood Readiness Standards have been developed to provide a more consistent definition of school readiness. The goal for the Standards is to provide early childhood educators…

Early Childhood Inclusion in Spain

ERIC Educational Resources Information Center

Giné, Climent; Balcells-Balcells, Anna; Cañadas, Margarita; Paniagua, Gema

2016-01-01

This article describes early childhood inclusion in educational settings in Spain. First, we address the legislative framework of preschool education in Spain and offer a brief analysis of some relevant issues, including the current situation of early childhood education and inclusion at this stage. Second, current policies and practices relating…

Teachers in Early Childhood Policy

ERIC Educational Resources Information Center

Kilderry, Anna

2014-01-01

This paper examines teacher accountability and authority in early childhood policy. It reports on data from a study that investigated the influences affecting early childhood teacher decision-making at the preschool level in Victoria, Australia. Using a question raised by Ball "Where are the teachers in all this [policy]?" provided a…

Missouri: Early Head Start Initiative

ERIC Educational Resources Information Center

Center for Law and Social Policy, Inc. (CLASP), 2012

2012-01-01

Missouri's Early Head Start/Child Care Partnership Project expands access to Early Head Start (EHS) services for children birth to age 3 by developing partnerships between federal Head Start, EHS contractors, and child care providers. Head Start and EHS contractors that participate in the initiative provide services through community child care…

ACHP | Section 106 Success Stories

Science.gov Websites

Casa Farnese "Creative Solution Preserves Integrity of Historic Development Project&quot -site mitigation solution." - Fort A.P. Hill, Caroline County, Virginia Franklin Post Office &quot "VA Medical Center: consultation leads to innovative solution." - Leavenworth, Kansas

77 FR 47897 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Granting Approval of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-10

... impact on efficiency, competition, and capital formation. See 15 U.S.C. 78c(f). \\8\\ 15 U.S.C. 78f(b)(5... that according to the ISE, each set of CMM quotes will have independent quoting obligations, and thus...

Further patient with Angelman syndrome due to paternal disomy of chromosome 15 and a milder phenotype

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gillessen-Kaesbach, G.; Passarge, E.; Horsthemke, B.

1995-04-10

This {open_quotes}Letter to the Editor{close_quotes} decribes a patient with Angelman syndrome due to paternal uniparental disomy of chromosome 15 and a milder phenotype compared to Angelman syndrome patients with a 15q deletion. 10 refs., 1 fig.

Early dynamics of transversally thermalized matter

NASA Astrophysics Data System (ADS)

Bialas, A.; Chojnacki, M.; Florkowski, W.

2008-10-01

We argue that the idea that the parton system created in relativistic heavy-ion collisions is formed in a state with transverse momenta close to thermodynamic equilibrium and its subsequent dynamics at early times is dominated by pure transverse hydrodynamics of the perfect fluid is compatible with the data collected at RHIC. This scenario of early parton dynamics may help to solve the problem of early equilibration. Quark Matter 2008, Jaipur, India, February 2008.

34 CFR 300.226 - Early intervening services.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Early intervening services. 300.226 Section 300.226... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility § 300.226 Early intervening services. (a... coordinated, early intervening services, which may include interagency financing structures, for students in...

Actionable Intelligence about Early Childhood Risks in Philadelphia

ERIC Educational Resources Information Center

LeBoeuf, Whitney A.; Barghaus, Katherine; Fantuzzo, John; Coe, Kristen; Brumley, Benjamin

2016-01-01

"Early childhood risks" are markers of early childhood experiences that extensive research has shown to be detrimental to later academic and behavioral outcomes. In Philadelphia, evidence indicates that seven early childhood risks tracked by public agencies have negative effects on early school outcomes. These risks include low…

Early Childhood Review: Papers from GAEC, 1996-1997.

ERIC Educational Resources Information Center

Cartwright, Penny, Ed.; Kelly, Clare, Ed.; McLean, Kathy, Ed.; Mellor, Nikki, Ed.; Pidgeon, Sue, Ed.; Stevens, Judith, Ed.; Stables, Kay, Ed.

1996-01-01

This periodical, from Goldsmiths Association for Early Childhood (GAEC), addresses a variety of issues related to early childhood education in Great Britain. Articles included in the Spring 1996 issue are: (1) "Traditional Story Telling in the Early Years" (Fiona Collins); (2) "International Focus--Early Childhood Education…

Early Childhood Intervention and Early Childhood Special Education in Turkey within the Scope of the Developmental System Approach

ERIC Educational Resources Information Center

Diken, Ibrahim H.; Bayhan, Pinar; Turan, Figen; Sipal, R. Firat; Sucuoglu, Bulbin; Ceber-Bakkaloglu, Hatice; Gunel, Mintaze Kerem; Kara, Ozgun Kaya

2012-01-01

The purpose of this article was to provide an overview of early childhood intervention and early childhood special education (ECI/ECSE) services and practices in Turkey by using the Developmental System Approach (M. J. Guralnick, 2001). After pointing out the history of early childhood and ECI/ECSE services and current legislations with regard to…

An Attempt to Standardize the Calculation of Growth Velocity of Preterm Infants-Evaluation of Practical Bedside Methods.

PubMed

Fenton, Tanis R; Anderson, Diane; Groh-Wargo, Sharon; Hoyos, Angela; Ehrenkranz, Richard A; Senterre, Thibault

2018-05-01

To examine how well growth velocity recommendations for preterm infants fit with current growth references: Fenton 2013, Olsen 2010, INTERGROWTH 2015, and the World Health Organization Growth Standard 2006. The Average (2-point), Exponential (2-point), Early (1-point) method weight-gains were calculated for 1,4,8,12, and 16-week time-periods. Growth references' weekly velocities (g/kg/d, gram/day and cm/week) were illustrated graphically with frequently-quoted 15 g/kg/d, 10-30 grams/day and 1 cm/week rates superimposed. The 15 g/kg/d and 1 cm/week growth velocity rates were calculated from 24-50 weeks, superimposed on the Fenton and Olsen preterm growth charts. The Average and Exponential g/kg/d estimates showed close agreement for all ages (range 5.0-18.9 g/kg/d), while the Early method yielded values as high as 41 g/kg/d. All 3 preterm growth references were similar to 15 g/kg/d rate at 34 weeks, but rates were higher prior and lower at older ages. For gram/day, the growth references changed from 10 to 30 grams/day for 24-33 weeks. Head growth rates generally fit the 1 cm/week velocity for 23-30 weeks, and length growth rates fit for 37-40 weeks. The calculated g/kg/d curves deviated from the growth charts, first downward, then steeply crossed the median curves near term. Human growth is not constant through gestation and early infancy. The frequently-quoted 15 g/kg/d, 10-30 gram/day and 1 cm/week only fit current growth references for limited time periods. Rates of 15-20 g/kg/d (calculated using average or exponential methods) are a reasonable goal for infants 23-36 weeks, but not beyond. Copyright © 2017 Elsevier Inc. All rights reserved.

Bioecological Theory, Early Child Development and the Validation of the Population-Level Early Development Instrument

ERIC Educational Resources Information Center

Guhn, Martin; Goelman, Hillel

2011-01-01

The Early Development Instrument (EDI; Janus and Offord in "Canadian Journal of Behavioural Science" 39:1-22, 2007) project is a Canadian population-level, longitudinal research project, in which teacher ratings of Kindergarten children's early development and wellbeing are linked to health and academic achievement variables at the…

39 CFR 775.7 - Planning and early coordination.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Planning and early coordination. 775.7 Section 775... POLICY ACT PROCEDURES § 775.7 Planning and early coordination. Early planning and coordination among... to the proposed action. Operational and facility personnel must cooperate in the early concept stages...

39 CFR 775.7 - Planning and early coordination.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Planning and early coordination. 775.7 Section 775... POLICY ACT PROCEDURES § 775.7 Planning and early coordination. Early planning and coordination among... to the proposed action. Operational and facility personnel must cooperate in the early concept stages...

Oaklahoma: Early Head Start Initiative

ERIC Educational Resources Information Center

Center for Law and Social Policy, Inc. (CLASP), 2012

2012-01-01

The Oklahoma Early Childhood Program uses public and private funds to enhance and expand high quality early care and education opportunities for children birth through age 3. The George Kaiser Family Foundation initiated the pilot in 2006 by matching state general revenue with private donations. Since that time, other private funders and providers…

Nebraska: Early Head Start Initiative

ERIC Educational Resources Information Center

Center for Law and Social Policy, Inc. (CLASP), 2012

2012-01-01

Since 1999, Nebraska's Early Head Start Infant/Toddler Quality Initiative has supported Early Head Start (EHS) and community child care partnerships to improve the quality and professionalism of infant and toddler care. EHS programs apply to receive funding to establish partnerships with center-based or home-based child care.The initiative has…

Teaching and Testing Early Reading. Focus On

ERIC Educational Resources Information Center

Mraz, Maryann; Kissel, Brian

2007-01-01

This issue of "Focus On" provides an overview of several key early literacy components: phonemic awareness, alphabet knowledge, concepts of print, oral language development, writing, family literacy, and reading aloud. Suggestions for assessing early literacy development are provided, and examples of implementation of effective early literacy…

Early bioenergetic evolution

PubMed Central

Sousa, Filipa L.; Thiergart, Thorsten; Landan, Giddy; Nelson-Sathi, Shijulal; Pereira, Inês A. C.; Allen, John F.; Lane, Nick; Martin, William F.

2013-01-01

Life is the harnessing of chemical energy in such a way that the energy-harnessing device makes a copy of itself. This paper outlines an energetically feasible path from a particular inorganic setting for the origin of life to the first free-living cells. The sources of energy available to early organic synthesis, early evolving systems and early cells stand in the foreground, as do the possible mechanisms of their conversion into harnessable chemical energy for synthetic reactions. With regard to the possible temporal sequence of events, we focus on: (i) alkaline hydrothermal vents as the far-from-equilibrium setting, (ii) the Wood–Ljungdahl (acetyl-CoA) pathway as the route that could have underpinned carbon assimilation for these processes, (iii) biochemical divergence, within the naturally formed inorganic compartments at a hydrothermal mound, of geochemically confined replicating entities with a complexity below that of free-living prokaryotes, and (iv) acetogenesis and methanogenesis as the ancestral forms of carbon and energy metabolism in the first free-living ancestors of the eubacteria and archaebacteria, respectively. In terms of the main evolutionary transitions in early bioenergetic evolution, we focus on: (i) thioester-dependent substrate-level phosphorylations, (ii) harnessing of naturally existing proton gradients at the vent–ocean interface via the ATP synthase, (iii) harnessing of Na+ gradients generated by H+/Na+ antiporters, (iv) flavin-based bifurcation-dependent gradient generation, and finally (v) quinone-based (and Q-cycle-dependent) proton gradient generation. Of those five transitions, the first four are posited to have taken place at the vent. Ultimately, all of these bioenergetic processes depend, even today, upon CO2 reduction with low-potential ferredoxin (Fd), generated either chemosynthetically or photosynthetically, suggesting a reaction of the type ‘reduced iron → reduced carbon’ at the beginning of bioenergetic evolution

Bipolar Disorder and Early Affective Trauma.

PubMed

de Codt, Aloise; Monhonval, Pauline; Bongaerts, Xavier; Belkacemi, Ikram; Tecco, Juan Martin

2016-09-01

Bipolar disorder is a chronic psychiatric disease with a high prevalence and is a major psychosocial and medical burden. The exact etiological pathways of bipolar disorder are not fully understood. Genetic factors are known to play an important role in the etiology of bipolar disorder. However, high rates of discordance among identical twins and a growing body of evidence that environmental factors such as early stress can influence the onset and course of psychiatric diseases underline the importance of additional etiological mechanisms of bipolar disorders. There has been little investigation about early trauma in bipolar disorder. The aim of this study was to review the literature on the association between early traumatic interactions like child neglect, mistreatment, abuse or early parental separation and the occurrence of bipolar disorder in adulthood or impact on the course of the disease. Studies investigating associations between child neglect, mistreatment, abuse or early parental separation and occurrence of bipolar disorder in adulthood or impact on the course of the disease were searched in the Pubmed database. More than 700 articles were sorted independently by two of the authors using predefined criteria. Only research articles, reviews and meta-analyses were selected for this review. 53 articles met the inclusion criteria. To date, four systematic reviews partially addressed our research question. Early trauma is more frequently found in the past of bipolar patients than in the general population. Studies support a harmful effect of childhood trauma on the course of bipolar disease, with more anxious, depressive or psychotic symptoms, an early age of onset and a worse prognosis. Early trauma is more often found in the past of bipolar adult patients than the general population and studies support a harmful effect of childhood trauma on the course of bipolar disease, with more anxious, depressive or psychotic symptoms, an early age of onset and a

New Directions in Intercultural Early Education in Australia

ERIC Educational Resources Information Center

Miller, Melinda; Petriwskyj, Anne

2013-01-01

Early education in Australia encompasses both early education and care (ECEC) and the early years of school. Educational approaches to cultural and linguistic diversity have varied not only by sector but also by jurisdiction based on distinct curriculum frameworks and policies. In Australian early education, provision for cultural and linguistic…

Family Income Dynamics, Early Childhood Education and Care, and Early Child Behavior Problems in Norway

ERIC Educational Resources Information Center

Zachrisson, Henrik D.; Dearing, Eric

2015-01-01

The sociopolitical context of Norway includes low poverty rates and universal access to subsidized and regulated Early Childhood Education and Care (ECEC). In this context, the association between family income dynamics and changes in early child behavior problems was investigated, as well as whether high-quality ECEC buffers children from the…

Validation of the Early Functional Abilities scale: An assessment of four dimensions in early recovery after traumatic brain injury.

PubMed

Poulsen, Ingrid; Kreiner, Svend; Engberg, Aase W

2018-02-13

The Early Functional Abilities scale assesses the restoration of brain function after brain injury, based on 4 dimensions. The primary objective of this study was to evaluate the validity, objectivity, reliability and measurement precision of the Early Functional Abilities scale by Rasch model item analysis. A secondary objective was to examine the relationship between the Early Functional Abilities scale and the Functional Independence Measurement™, in order to establish the criterion validity of the Early Functional Abilities scale and to compare the sensitivity of measurements using the 2 instruments. The Rasch analysis was based on the assessment of 408 adult patients at admission to sub-acute rehabilitation in Copenhagen, Denmark after traumatic brain injury. The Early Functional Abilities scale provides valid and objective measurement of vegetative (autonomic), facio-oral, sensorimotor and communicative/cognitive functions. Removal of one item from the sensorimotor scale confirmed unidimensionality for each of the 4 subscales, but not for the entire scale. The Early Functional Abilities subscales are sensitive to differences between patients in ranges in which the Functional Independence Measurement™ has a floor effect. The Early Functional Abilities scale assesses the early recovery of important aspects of brain function after traumatic brain injury, but is not unidimensional. We recommend removal of the "standing" item and calculation of summary subscales for the separate dimensions.

Fossil evidence for a herbaceous diversification of early eudicot angiosperms during the Early Cretaceous

PubMed Central

Jud, Nathan A.

2015-01-01

Eudicot flowering plants comprise roughly 70% of land plant species diversity today, but their early evolution is not well understood. Fossil evidence has been largely restricted to their distinctive tricolpate pollen grains and this has limited our understanding of the ecological strategies that characterized their primary radiation. I describe megafossils of an Early Cretaceous eudicot from the Potomac Group in Maryland and Virginia, USA that are complete enough to allow reconstruction of important life-history traits. I draw on quantitative and qualitative analysis of functional traits, phylogenetic analysis and sedimentological evidence to reconstruct the biology of this extinct species. These plants were small and locally rare but widespread, fast-growing herbs. They had complex leaves and they were colonizers of bright, wet, disturbance-prone habitats. Other early eudicot megafossils appear to be herbaceous rather than woody, suggesting that this habit was characteristic of their primary radiation. A mostly herbaceous initial diversification of eudicots could simultaneously explain the heretofore sparse megafossil record as well as their rapid diversification during the Early Cretaceous because the angiosperm capacity for fast reproduction and fast evolution is best expressed in herbs. PMID:26336172

Fossil evidence for a herbaceous diversification of early eudicot angiosperms during the Early Cretaceous.

PubMed

Jud, Nathan A

2015-09-07

Eudicot flowering plants comprise roughly 70% of land plant species diversity today, but their early evolution is not well understood. Fossil evidence has been largely restricted to their distinctive tricolpate pollen grains and this has limited our understanding of the ecological strategies that characterized their primary radiation. I describe megafossils of an Early Cretaceous eudicot from the Potomac Group in Maryland and Virginia, USA that are complete enough to allow reconstruction of important life-history traits. I draw on quantitative and qualitative analysis of functional traits, phylogenetic analysis and sedimentological evidence to reconstruct the biology of this extinct species. These plants were small and locally rare but widespread, fast-growing herbs. They had complex leaves and they were colonizers of bright, wet, disturbance-prone habitats. Other early eudicot megafossils appear to be herbaceous rather than woody, suggesting that this habit was characteristic of their primary radiation. A mostly herbaceous initial diversification of eudicots could simultaneously explain the heretofore sparse megafossil record as well as their rapid diversification during the Early Cretaceous because the angiosperm capacity for fast reproduction and fast evolution is best expressed in herbs. © 2015 The Author(s).

Early Childhood Inclusion in the United Kingdom

ERIC Educational Resources Information Center

Blackburn, Carolyn

2016-01-01

A policy-to-practice paper is presented of early childhood inclusion in England. The article aims to report the benefits of early intervention services and early childhood inclusion for children with special educational needs and disabilities (SEND), document the chronology of policy development, and discuss research evidence about…

34 CFR 300.711 - Early intervening services.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Early intervening services. 300.711 Section 300.711... Secretary of the Interior § 300.711 Early intervening services. (a) The Secretary of the Interior may allow... funds), to develop and implement coordinated, early intervening services, which may include interagency...

34 CFR 300.226 - Early intervening services.

Code of Federal Regulations, 2010 CFR

2010-07-01

... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility § 300.226 Early intervening services. (a... annually report to the SEA on— (1) The number of children served under this section who received early intervening services; and (2) The number of children served under this section who received early intervening...

34 CFR 303.11 - Early intervention program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Early intervention program. 303.11 Section 303.11... AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EARLY INTERVENTION PROGRAM FOR INFANTS AND... intervention program. As used in this part, early intervention program means the total effort in a State that...

34 CFR 303.11 - Early intervention program.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Early intervention program. 303.11 Section 303.11... AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EARLY INTERVENTION PROGRAM FOR INFANTS AND... intervention program. As used in this part, early intervention program means the total effort in a State that...

Depressive Symptomatology among Very Early Maturing Girls.

ERIC Educational Resources Information Center

Rierdan, Jill; Koff, Elissa

1991-01-01

The relationship between very early menarche and depression was studied in a sample of 488 girls (336 sixth graders and 152 seventh graders), less than 10 percent of whom were very early maturers. Very early menarche was associated with higher levels of depression than was more normative development. (SLD)

Inside story on the legal challenge to EPA`s municipal waste combustor rule: The mouse that roared, Round 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jenkins, L.S.

1997-12-01

An article in the Deseret News, one of two general circulation newspapers in Salt Lake City, Utah, dated December 13, 1996, reported that {open_quotes}David{close_quotes} took on {open_quotes}Goliath{close_quotes} and won. The article referred to the Davis County Solid Waste Management and Energy Recovery Special Service District`s (the {open_quotes}District{close_quotes}) victory on its challenge to the EPA`s municipal waste combustor rules. On December 6, 1996, the United States Court of Appeals for the District of Columbia Circuit ruled that the EPA violated the plain language of Section 129 of the Clean Air Act, when it wrote size categories for municipal waste combustors ({open_quotes}MWCs{close_quotes})more » based on aggregate plant capacity, rather than unit capacity. The District argued that Congress divided the universe of MWC units into two categories: those with unit capacities above 250 tons per day, and those with unit capacities equal to or less than 250 tons per day. The EPA, however, had set the dividing line at 248 tons per day aggregate plant capacity in its municipal waste combustor rule. The Court said this was wrong. The Deseret News report certainly echoed the feelings of the District. Those of you familiar with the EPA, the process of judicial review of administrative rule making, and the Biblical story of David and Goliath, however, will quickly see that this is not the best metaphor to describe what happened. When David slew Goliath, that was the end of Goliath. He didn`t get back up. Of course, that will not happen to the EPA in the Davis County case. Like an 800-pound gorilla, it will always get back up after being challenged by a mouse. This paper tells the story of the challenge to the MWC rule from the District`s perspective. The District has not been popular with either the EPA or many industry players. But, the District was faced with a real problem that, given the District`s location and the local economy, forced its hand in this

Arizona Early Childhood Education Standards.

ERIC Educational Resources Information Center

Arizona State Dept. of Education, Phoenix.

In an effort to provide a sound basis for educational accountability for preschool programs, the Arizona Early Childhood Education (ECE) Standards were developed as a framework for literacy-based programs for 3- and 4-year-olds and to provide parents with a basic understanding of indicators of early learning. These standards, to be adopted by…

An early Cambrian greenhouse climate.

PubMed

Hearing, Thomas W; Harvey, Thomas H P; Williams, Mark; Leng, Melanie J; Lamb, Angela L; Wilby, Philip R; Gabbott, Sarah E; Pohl, Alexandre; Donnadieu, Yannick

2018-05-01

The oceans of the early Cambrian (~541 to 509 million years ago) were the setting for a marked diversification of animal life. However, sea temperatures-a key component of the early Cambrian marine environment-remain unconstrained, in part because of a substantial time gap in the stable oxygen isotope (δ 18 O) record before the evolution of euconodonts. We show that previously overlooked sources of fossil biogenic phosphate have the potential to fill this gap. Pristine phosphatic microfossils from the Comley Limestones, UK, yield a robust δ 18 O signature, suggesting sea surface temperatures of 20° to 25°C at high southern paleolatitudes (~65°S to 70°S) between ~514 and 509 million years ago. These sea temperatures are consistent with the distribution of coeval evaporite and calcrete deposits, peak continental weathering rates, and also our climate model simulations for this interval. Our results support an early Cambrian greenhouse climate comparable to those of the late Mesozoic and early Cenozoic, offering a framework for exploring the interplay between biotic and environmental controls on Cambrian animal diversification.

Anti-early pregnancy by PDT

NASA Astrophysics Data System (ADS)

Ding, Ai-Hua; Chen, Hui-Ling

1993-03-01

The effect of laser on anti-early pregnancy in rabbits showed that laser in combination with HPD could induce necrosis of blastocysts and complete absorption. The anti-fertility efficiency of the combined treatment was more effective than that of the He-Ne laser or the HPD treatment alone. The fluorescence spectrum of HPD determined by PNQ3 showed that its affinity to embryonic tissue was about 4 times greater than that to uterine tissue. This may underlie the mechanisms of anti-early pregnancy of the laser. The operation of artificial abortion is a routine method to terminate early pregnancy. Though it is simple and easy, its syndrome and complications can not be absolutely avoided. Many antifertility drugs have been reported, however, they often bring in general reaction. Our present work is to explore a new way of anti-early pregnancy in rabbits by means of the light inhibitory and light sensitive effects of laser. It is a quite safe and painless treatment without expanding and scraping of the uterus.