Tight Left Upper Lobe Collapse from Lung Cancer
2010-07-01
misinterpreted or overlooked on chest radiographs. In reviewing lobar collapse, a typical cause is from proximal occlusion or stenosis of a lobar...common causes include fibrotic stenosis from granulomatous disease, post- radiation bronchial stenosis , and inflammatory conditions (eg. polychondritis...pleural space. On frontal radiograph, a cresentic hyperlucency may be noted adjacent to the thoracic aortic arch in about half of cases
O'Halloran, Ken D; Lewis, Philip; McDonald, Fiona
2017-11-01
Obstructive sleep apnoea syndrome (OSAS) is a devastating respiratory control disorder more common in men than women. The reasons for the sex difference in prevalence are multifactorial, but are partly attributable to protective effects of oestrogen. Indeed, OSAS prevalence increases in post-menopausal women. OSAS is characterized by repeated occlusions of the pharyngeal airway during sleep. Dysfunction of the upper airway muscles controlling airway calibre and collapsibility is implicated in the pathophysiology of OSAS, and sex differences in the neuro-mechanical control of upper airway patency are described. It is widely recognized that chronic intermittent hypoxia (CIH), a cardinal feature of OSAS due to recurrent apnoea, drives many of the morbid consequences characteristic of the disorder. In rodents, exposure to CIH-related redox stress causes upper airway muscle weakness and fatigue, associated with mitochondrial dysfunction. Of interest, in adults, there is female resilience to CIH-induced muscle dysfunction. Conversely, exposure to CIH in early life, results in upper airway muscle weakness equivalent between the two sexes at 3 and 6 weeks of age. Ovariectomy exacerbates the deleterious effects of exposure to CIH in adult female upper airway muscle, an effect partially restored by oestrogen replacement therapy. Intriguingly, female advantage intrinsic to upper airway muscle exists with evidence of substantially greater loss of performance in male muscle during acute exposure to severe hypoxic stress. Sex differences in upper airway muscle physiology may have relevance to human OSAS. The oestrogen-oestrogen receptor α axis represents a potential therapeutic target in OSAS, particularly in post-menopausal women. Copyright © 2016 Elsevier B.V. All rights reserved.
Mid-tertiary ash flow tuff cauldrons, southwestern New Mexico
NASA Technical Reports Server (NTRS)
Elston, W. E.
1984-01-01
Characteristics of 28 known or suspected mid-Tertiary ash-flow tuff cauldrons in New Mexico are described. The largest region is 40 km in diameter, and erosional and block faulting processes have exposed levels as far down as the plutonic roots. The study supports a five-stage process: precursor, caldera collapse, early post-collapse, volcanism, major ring-fracture volcanism, and hydrothermal activity. The stages can repeat or the process can stop at any stage. Post-collapse lavas fell into two categories: cauldron lavas, derived from shallow defluidized residues of caldera-forming ash flow tuff eruption, and framework lavas, evolved from a siliceous pluton below the cauldron complex. The youngest caldera was shallow and formed from asymmetric subsidence and collapse of the caldera walls.
Convective radiation fluid-dynamics: formation and early evolution of ultra low-mass objects
NASA Astrophysics Data System (ADS)
Wuchterl, G.
2005-12-01
The formation process of ultra low-mass objects is some kind of extension of the star formation process. The physical changes towards lower mass are discussed by investigating the collapse of cloud cores that are modelled as Bonnor-Ebert spheres. Their collapse is followed by solving the equations of fluid dynamics with radiation and a model of time-dependent convection that has been calibrated to the Sun. For a sequence of cloud-cores with 1 to 0.01 solar masses, evolutionary tracks and isochrones are shown in the mass-radius diagram, the Hertzsprung-Russel diagram and the effective temperature-surface gravity or Kiel diagram. The collapse and the early hydrostatic evolution to ages of few Ma are briefly discussed and compared to observations of objects in Upper Scorpius and the low-mass components of GG Tau.
Terrane accumulation and collapse in central Europe: seismic and rheological constraints
NASA Astrophysics Data System (ADS)
Meissner, R.
1999-05-01
An attempt is made to compare the tectonic units and their evolution in central Europe with the deep seismic velocity structure and patterns of reflectivity. Caledonian and Variscan terrane accretion and orogenic collapse dominate the tectonic development in central and western Europe and have left their marks in a distinct velocity structure and crustal thickness as well as in the various reflectivity patterns. Whereas the memory of old collisional structures is still preserved in the rigid upper crust, collapse processes have formed and modified the lower crust. They have generally created rejuvenated, thin crusts with shallow Mohos. In the Variscan internides, the center of collision and post-orogenic heat pulses, the lower crust developed strong and thick seismic lamellae, the (cooler) externides show a thrust and shear pattern in the whole crust, and the North German Basin experienced large mafic intrusions in the lower crust and developed a high-velocity structure with only very thin lamellae on top of the Moho. The various kinds of reflectivity patterns in the lithosphere can be explained by a thermo-rheological model from terrane collision, with crustal thickening to collapse in a hot, post-orogenic setting.
NASA Astrophysics Data System (ADS)
Vellekoop, Johan; Woelders, Lineke; Açikalin, Sanem; Smit, Jan; van de Schootbrugge, Bas; Yilmaz, Ismail Ö.; Brinkhuis, Henk; Speijer, Robert P.
2017-02-01
It is commonly accepted that the mass extinction associated with the Cretaceous-Paleogene (K-Pg) boundary (˜ 66 Ma) is related to the environmental effects of a large extraterrestrial impact. The biological and oceanographic consequences of the mass extinction are, however, still poorly understood. According to the Living Ocean
model, the biological crisis at the K-Pg boundary resulted in a long-term reduction of export productivity in the early Paleocene. Here, we combine organic-walled dinoflagellate cyst (dinocyst) and benthic foraminiferal analyses to provide new insights into changes in the coupling of pelagic and benthic ecosystems. To this end, we perform dinocyst and benthic foraminiferal analyses on the recently discovered Tethyan K-Pg boundary section at Okçular, Turkey, and compare the results with other K-Pg boundary sites in the Tethys. The post-impact dominance of epibenthic morphotypes and an increase of inferred heterotrophic dinocysts in the early Paleocene at Okçular are consistent with published records from other western Tethyan sites. Together, these records indicate that during the early Paleocene more nutrients remained available for the Tethyan planktonic community, whereas benthic communities were deprived of food. Hence, in the post-impact phase the reduction of export productivity likely resulted in enhanced recycling of nutrients in the upper part of the water column, all along the western Tethyan margins.
Piercing the upper ear: a simple infection, a difficult reconstruction.
Cicchetti, S; Skillman, J; Gault, D T
2002-04-01
Piercing the upper ear to retain jewellery is now commonplace. When infection ensues, devastating chondritis leads to collapse of the ear. To our knowledge, the surgical reconstruction of post-piercing deformities has not been documented in the literature. We present five such cases referred for autogenous-tissue ear reconstruction. In four of these, the destroyed segments of ear cartilage were replaced with a carved costal-cartilage framework. One patient declined surgery. The importance of preventing infection is stressed. Copyright 2002 The British Association of Plastic Surgeons.
Till, A.B.; Harris, A.G.; Wardlaw, B.R.; Mullen, M.
2007-01-01
Reexamination of existing conodont collections from the central Alaska Range indicates that Upper Triassic marine slope and basin rocks range in age from at least as old as the late Carnian to the early middle Norian. The conodont assemblages typical of these rocks are generally cosmopolitan and do not define a distinct paleogeographic faunal realm. One collection, however, containsEpigondolella multidentata sensu Orchard 1991c, which appears to be restricted to western North American autochthonous rocks. Although paleogeographic relations cannot be determined with specificity, the present distribution of biofaces within the Upper Triassic sequence could not have been the result of simple accordion-style collapse of the Late Triassic margin.
Taranto-Montemurro, Luigi; Sands, Scott A.; Edwards, Bradley A.; Azarbarzin, Ali; Marques, Melania; de Melo, Camila; Eckert, Danny J.; White, David P.; Wellman, Andrew
2017-01-01
We recently demonstrated that desipramine reduces the sleep-related loss of upper airway dilator muscle activity and reduces pharyngeal collapsibility in healthy humans without obstructive sleep apnoea (OSA). The aim of the present physiological study was to determine the effects of desipramine on upper airway collapsibility and apnoea–hypopnea index (AHI) in OSA patients. A placebo-controlled, double-blind, randomised crossover trial in 14 OSA patients was performed. Participants received treatment or placebo in randomised order before sleep. Pharyngeal collapsibility (critical collapsing pressure of the upper airway (Pcrit)) and ventilation under both passive (V′0,passive) and active (V′0,active) upper airway muscle conditions were evaluated with continuous positive airway pressure (CPAP) manipulation. AHI was quantified off CPAP. Desipramine reduced active Pcrit (median (interquartile range) −5.2 (4.3) cmH2O on desipramine versus −1.9 (2.7) cmH2O on placebo; p=0.049) but not passive Pcrit (−2.2 (3.4) versus −0.7 (2.1) cmH2O; p=0.135). A greater reduction in AHI occurred in those with minimal muscle compensation (defined as V′0,active−V′0, passive) on placebo (r=0.71, p=0.009). The reduction in AHI was driven by the improvement in muscle compensation (r=0.72, p=0.009). In OSA patients, noradrenergic stimulation with desipramine improves pharyngeal collapsibility and may be an effective treatment in patients with minimal upper airway muscle compensation. PMID:27799387
Landry, Shane A; Joosten, Simon A; Eckert, Danny J; Jordan, Amy S; Sands, Scott A; White, David P; Malhotra, Atul; Wellman, Andrew; Hamilton, Garun S; Edwards, Bradley A
2017-06-01
Upper airway collapsibility is a key determinant of obstructive sleep apnea (OSA) which can influence the efficacy of certain non-continuous positive airway pressure (CPAP) treatments for OSA. However, there is no simple way to measure this variable clinically. The present study aimed to develop a clinically implementable tool to evaluate the collapsibility of a patient's upper airway. Collapsibility, as characterized by the passive pharyngeal critical closing pressure (Pcrit), was measured in 46 patients with OSA. Associations were investigated between Pcrit and data extracted from patient history and routine polysomnography, including CPAP titration. Therapeutic CPAP level, demonstrated the strongest relationship to Pcrit (r2=0.51, p < .001) of all the variables investigated including apnea-hypopnea index, body mass index, sex, and age. Patients with a mildly collapsible upper airway (Pcrit ≤ -2 cmH2O) had a lower therapeutic CPAP level (6.2 ± 0.6 vs. 10.3 ± 0.4 cmH2O, p < .001) compared to patients with more severe collapsibility (Pcrit > -2 cmH2O). A therapeutic CPAP level ≤8.0 cmH2O was sensitive (89%) and specific (84%) for detecting a mildly collapsible upper airway. When applied to the independent validation data set (n = 74), this threshold maintained high specificity (91%) but reduced sensitivity (75%). Our data demonstrate that a patient's therapeutic CPAP requirement shares a strong predictive relationship with their Pcrit and may be used to accurately differentiate OSA patients with mild airway collapsibility from those with moderate-to-severe collapsibility. Although this relationship needs to be confirmed prospectively, our findings may provide clinicians with better understanding of an individual patient's OSA phenotype, which ultimately could assist in determining which patients are most likely to respond to non-CPAP therapies. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.
Upper Airway Collapsibility (Pcrit) and Pharyngeal Dilator Muscle Activity are Sleep Stage Dependent
Carberry, Jayne C.; Jordan, Amy S.; White, David P.; Wellman, Andrew; Eckert, Danny J.
2016-01-01
Study Objectives: An anatomically narrow/highly collapsible upper airway is the main cause of obstructive sleep apnea (OSA). Upper airway muscle activity contributes to airway patency and, like apnea severity, can be sleep stage dependent. Conversely, existing data derived from a small number of participants suggest that upper airway collapsibility, measured by the passive pharyngeal critical closing pressure (Pcrit) technique, is not sleep stage dependent. This study aimed to determine the effect of sleep stage on Pcrit and upper airway muscle activity in a larger cohort than previously tested. Methods: Pcrit and/or muscle data were obtained from 72 adults aged 20–64 y with and without OSA.Pcrit was determined via transient reductions in continuous positive airway pressure (CPAP) during N2, slow wave sleep (SWS) and rapid eye movement (REM) sleep. Genioglossus and tensor palatini muscle activities were measured: (1) awake with and without CPAP, (2) during stable sleep on CPAP, and (3) in response to the CPAP reductions used to quantify Pcrit. Results: Pcrit was 4.9 ± 1.4 cmH2O higher (more collapsible) during REM versus SWS (P = 0.012), 2.3 ± 0.6 cmH2O higher during REM versus N2 (P < 0.001), and 1.6 ± 0.7 cmH2O higher in N2 versus SWS (P = 0.048). Muscle activity decreased from wakefulness to sleep and from SWS to N2 to REM sleep for genioglossus but not for tensor palatini. Pharyngeal muscle activity increased by ∼50% by breath 5 following CPAP reductions. Conclusions: Upper airway collapsibility measured via the Pcrit technique and genioglossus muscle activity vary with sleep stage. These findings should be taken into account when performing and interpreting “passive” Pcrit measurements. Citation: Carberry JC, Jordan AS, White DP, Wellman A, Eckert DJ. Upper airway collapsibility (Pcrit) and pharyngeal dilator muscle activity are sleep stage dependent. SLEEP 2016;39(3):511–521. PMID:26612386
Barnett, T P; O'Leary, J M; Parkin, T D H; Dixon, P M; Barakzai, S Z
2013-09-01
To investigate upper respiratory tract function in horses, previously undergoing laryngoplasty (LP), using exercising video-endoscopy. To evaluate arytenoid abduction and stability, diagnose any concurrent upper airway problems, and correlate these with the owners' perception of success. Horses undergoing LP during a 6-year period at one hospital were initially included. Those available for re-examination were exercised for a duration and intensity considered maximal for their discipline using an over-ground endoscope. Resting and exercising laryngeal and pharyngeal videos were analysed blindly. Multivariable analysis was used to test associations between resting and exercising endoscopic variables, and also between endoscopic variables and owner questionnaire findings. Forty-one horses were included and 78% had a form of upper airway collapse at exercise, with 41% having complex forms, despite 93% of owners reporting the surgery to have been beneficial. Horses with poor abduction (grades 4 or 5/5) were 6 times more likely to make respiratory noise compared with those with good (grades 2 or 3/5) abduction (P = 0.020; 95% confidence interval [CI] 1.3-27.0), and those not having a ventriculectomy were 4.9 times more likely to produce respiratory noise post operatively (P = 0.048; 95% CI 1.0-23.9). Palatal dysfunction was observed in 24% of horses at rest, and 56% at exercise, with the diagnosis at rest and exercise significantly associated (P = 0.001). Increasing severity of pharyngeal lymphoid hyperplasia (prevalence 61%) was significantly associated with increasing arytenoid abduction (P = 0.01). Thirty-four per cent of horses had aryepiglottic fold collapse and 22% of horses had vocal fold collapse. Many horses that had previously had LP were diagnosed with upper airway abnormalities, despite the procedure being considered as beneficial by most owners. When investigating cases of ongoing respiratory noise or poor performance following LP, exercising endoscopy must be considered. Continued respiratory noise may be associated with poor arytenoid abduction and not performing concurrent ventriculectomy. © 2012 EVJ Ltd.
Early post-operative cerebrospinal fluid hypovolemia: Report of 7 cases.
Hou, Kun; Zhu, Xiaobo; Zhang, Yang; Gao, Xianfeng; Suo, Shihuan; Zhao, Jinchuan; Li, Guichen
2018-06-01
Cerebrospinal fluid (CSF) hypovolemia is a common neurosurgical condition, which may be spontaneous or iatrogenic. At our institution, a substantial number of the reported cases of early post-operative CSF hypovolemia were identified to have unintentional or unrecognized post-operative continuous excessive CSF leakage. Cases who presented with post-operative CSF hypovolemia several days after uneventful intracranial surgeries without continuous CSF leakage were rarely reported. A retrospective review of the medical records of these patients was performed to identify those patients who developed early post-operative CSF hypovolemia without the presence of post-operative continuous CSF leakage. A total of 7 patients, 5 of which were males, were identified in this retrospective study. They experienced CSF hypovolemia between days 1 and 7 after emergency or scheduled intracranial surgeries. Ventricular collapse, cisternal effacement and midline shift are the most common radiological observations. With early diagnosis and management, 4 of the patients achieved a Glasgow Outcome Scale (GOS) score of 5, 1 achieved a GOS score of 4 and the remaining 2 had a GOS score of 3. No mortality was noted in this series. Although rare in incidence, early post-operative CSF hypovolemia may occur without the existence of post-operative continuous CSF leakage. When the diagnosis of CSF hypovolemia is reached, factors that may exacerbate CSF compensation should be promptly terminated. Trendelenburg position and sufficient intravenous hydration are practical and effective managements, and CSF hypovolemia may thereby be reversed in a substantial number of patients.
Caldera formation at Volcán Colima, Mexico, by a large large holocene volcanic debris avalanche
NASA Astrophysics Data System (ADS)
Luhr, James F.; Prestegaard, Karen L.
1988-12-01
About 4,300 years ago, 10 km 3 of the upper cone of ancestral Volcán Colima collapsed to the southwest leaving a horseshoe-shaped caldera 4 km in diameter. The collapse produced a massive volcanic debris avalanche deposit covering over 1550 km 2 on the southern flanks of the volcano and extending at least 70 km from the former summit. The avalanche followed a steep topographic gradient unobstructed by barriers, resulting in an unusually high area/volume ratio for the Colima deposit. The apparent coefficient of friction (fall height/distance traveled) for the Colima avalanche is 0.06, a low value similar to those of other large-volume deposits. The debris avalanche deposit contains 40-75% angular volcanic clasts from the ancestral cone, a small proportion of vesicular blocks that may be juvenile, and in distal exposures, rare carbonate clasts plucked from the underlying surface by the moving avalanche. Clasts range in size to over 20 m in diameter and are brecciated to different degrees, pulverized, and surrounded by a rock-flour matrix. The upper surface of the deposit shows prominent hummocky topography with closed depressions and surface boulders. A thick, coarse-grained, compositionally zoned scoria-fall layer on the upper northeastern slope of the volcano may have erupted at the time of collapse. A fine-grained surge layer is present beneath the avalanche deposit at one locality, apparently representing an initial blast event. Most of the missing volume of the ancestral volcano has since been restored at an average rate of 0.002 km 3/yr through repeated eruptions from the post-caldera cone. As a result, the southern slope of Volcán Colima may again be susceptible to collapse. Over 200,000 people are now living on primary or secondary deposits of the debris avalanche, and a repetition of this event would constitute a volcanic disaster of great magnitude. Ancestral Volcán Colima grew on the southern, trenchward flank of the earlier and larger volcano Nevado de Colima. Trenchward collapse was favored by the buttressing effect of Nevado, the rapid elevation drop to the south, and the intrusion of magma into the southern flank of the ancestral volcano. Other such trenchward-younging, paired volcanoes are known from Mexico, Guatemala, El Salvador, Chile, and Japan. The trenchward slopes of the younger cones are common sites for cone collapse to form avalanche deposits, as occurred at Colima and Popocatepetl in Mexico and at San Pedro Volcano in Chile.
Andara, Christopher; Landry, Shane; Sands, Scott A.; Joosten, Simon A.; Owens, Robert L.; White, David P.; Hamilton, Garun S.; Wellman, Andrew
2016-01-01
Rationale: Oral appliances (OAs) are commonly used as an alternative treatment to continuous positive airway pressure for patients with obstructive sleep apnea (OSA). However, OAs have variable success at reducing the apnea–hypopnea index (AHI), and predicting responders is challenging. Understanding this variability may lie with the recognition that OSA is a multifactorial disorder and that OAs may affect more than just upper-airway anatomy/collapsibility. Objectives: The objectives of this study were to determine how OA alters AHI and four phenotypic traits (upper-airway anatomy/collapsibility and muscle function, loop gain, and arousal threshold), and baseline predictors of which patients gain the greatest benefit from therapy. Methods: In a randomized crossover study, 14 patients with OSA attended two sleep studies with and without their OA. Under each condition, AHI and the phenotypic traits were assessed. Multiple linear regression was used to determine independent predictors of the reduction in AHI. Measurements and Main Results: OA therapy reduced the AHI (30 ± 5 vs. 11 ± 2 events/h; P < 0.05), which was driven by improvements in upper-airway anatomy/collapsibility under passive (1.9 ± 0.7 vs. 4.7 ± 0.6 L/min; P < 0.005) and active conditions (2.4 ± 0.9 vs. 6.2 ± 0.4 L/min; P < 0.001). No changes were seen in muscle function, loop gain, or the arousal threshold. Using multivariate analysis, baseline passive upper-airway collapsibility and loop gain were independent predictors of the reduction in AHI (r2 = 0.70; P = 0.001). Conclusions: Our findings suggest that OA therapy improves the upper-airway collapsibility under passive and active conditions. Importantly, a greater response to therapy occurred in those patients with a mild anatomic compromise and a lower loop gain. PMID:27181367
Childhood bone tuberculosis from Roman Pécs, Hungary.
Hlavenková, L; Teasdale, M D; Gábor, O; Nagy, G; Beňuš, R; Marcsik, A; Pinhasi, R; Hajdu, T
2015-02-01
A child from a Roman necropolis in Pécs, Hungary (4th century CE) was initially diagnosed with severe spinal osteomyelitis. The post-cranial skeleton displayed bone alterations in the lower thoracic and upper lumbar segments, including vertebral body destruction, collapse and sharp kyphosis, and additional multiple rib lesions, suggesting a most likely diagnosis of pulmonary and spinal tuberculosis. This study discusses a number of selected diagnoses in the context of our pathological findings, complementing the macroscopic examination with radiological and biomolecular analyses. Copyright © 2014 Elsevier GmbH. All rights reserved.
After the Fall: The Dust and Gas in E+A Post-starburst Galaxies
NASA Astrophysics Data System (ADS)
Smercina, A.; Smith, J. D. T.; Dale, D. A.; French, K. D.; Croxall, K. V.; Zhukovska, S.; Togi, A.; Bell, E. F.; Crocker, A. F.; Draine, B. T.; Jarrett, T. H.; Tremonti, C.; Yang, Yujin; Zabludoff, A. I.
2018-03-01
The traditional picture of post-starburst galaxies as dust- and gas-poor merger remnants, rapidly transitioning to quiescence, has been recently challenged. Unexpected detections of a significant interstellar medium (ISM) in many post-starburst galaxies raise important questions. Are they truly quiescent, and if so, what mechanisms inhibit further star formation? What processes dominate their ISM energetics? We present an infrared spectroscopic and photometric survey of 33 E+A post-starbursts selected by the Sloan Digital Sky Survey, aimed at resolving these questions. We find compact, warm dust reservoirs with high PAH abundances and total gas and dust masses significantly higher than expected from stellar recycling alone. Both polycyclic aromatic hydrocarbon (PAH)/total infrared (TIR) and dust-to-burst stellar mass ratios are seen to decrease with post-burst age, indicative of the accumulating effects of dust destruction and an incipient transition to hot, early-type ISM properties. Their infrared spectral properties are unique, with dominant PAH emission, very weak nebular lines, unusually strong H2 rotational emission, and deep [C II] deficits. There is substantial scatter among star formation rate (SFR) indicators, and both PAH and TIR luminosities provide overestimates. Even as potential upper limits, all tracers show that the SFR has typically experienced a decline of more than two orders of magnitude since the starburst and that the SFR is considerably lower than expected given both their stellar masses and molecular gas densities. These results paint a coherent picture of systems in which star formation was, indeed, rapidly truncated, but in which the ISM was not completely expelled, and is instead supported against collapse by latent or continued injection of turbulent or mechanical heating. The resulting aging burst populations provide a “high-soft” radiation field that seemingly dominates the E+A galaxies’ unusual ISM energetics.
Lobar analysis of collapsibility indices to assess functional lung volumes in COPD patients.
Kitano, Mariko; Iwano, Shingo; Hashimoto, Naozumi; Matsuo, Keiji; Hasegawa, Yoshinori; Naganawa, Shinji
2014-01-01
We investigated correlations between lung volume collapsibility indices and pulmonary function test (PFT) results and assessed lobar differences in chronic obstructive pulmonary disease (COPD) patients, using paired inspiratory and expiratory three dimensional (3D) computed tomography (CT) images. We retrospectively assessed 28 COPD patients who underwent paired inspiratory and expiratory CT and PFT exams on the same day. A computer-aided diagnostic system calculated total lobar volume and emphysematous lobar volume (ELV). Normal lobar volume (NLV) was determined by subtracting ELV from total lobar volume, both for inspiratory phase (NLVI) and for expiratory phase (NLVE). We also determined lobar collapsibility indices: NLV collapsibility ratio (NLVCR) (%)=(1-NLVE/NLVI)×100%. Associations between lobar volumes and PFT results, and collapsibility indices and PFT results were determined by Pearson correlation analysis. NLVCR values were significantly correlated with PFT results. Forced expiratory volume in 1 second, measured as percent of predicted results (FEV1%P) was significantly correlated with NLVCR values for the lower lobes (P<0.01), whereas this correlation was not significant for the upper lobes (P=0.05). FEV1%P results were also moderately correlated with inspiratory, expiratory ELV (ELVI,E) for the lower lobes (P<0.05). In contrast, the ratio of the diffusion capacity for carbon monoxide to alveolar gas volume, measured as percent of predicted (DLCO/VA%P) results were strongly correlated with ELVI for the upper lobes (P<0.001), whereas this correlation with NLVCR values was weaker for upper lobes (P<0.01) and was not significant for the lower lobes (P=0.26). FEV1%P results were correlated with NLV collapsibility indices for lower lobes, whereas DLCO/VA%P results were correlated with NLV collapsibility indices and ELV for upper lobes. Thus, evaluating lobar NLV collapsibility might be useful for estimating pulmonary function in COPD patients.
Jia, Yi-lin; Fu, Min-kui; Ma, Lian
2004-05-01
To examine the effect of pre-surgical orthodontics on the outcome of the secondary alveolar bone grafting in the patients with complete cleft lip and palate. Sixteen complete cleft lip and palate patients (9 males and 7 females) with collapsed upper arch or severe mal-positioned upper incisors were selected. The cleft was not easily grafted because of the poor access. The total cleft sites were 22 (10 patients with UCLP and 6 patients with BCLP). The age range of the patients was from 8 to 22 years. Pre-surgical orthodontic treatment was mainly to expand the collapsed upper arch and correct the mal-positioned upper incisors. After the secondary alveolar bone grafting, the patients were followed up and anterior occlusal radiograph/intraoral panograph were taken regularly. The observation period was from 6 months to 4 years. Bergland criteria were used to evaluate the interdental septal height. Upper arch expansion and the correction of the mal-positioned upper incisors done by the orthodontic treatment made the bone grafting procedure easier. The clinically successful rate reached 86%. The severe upper arch collapse and mal-positioned upper incisors in the patients with complete cleft lip and palate should be corrected orthodontically before the secondary alveolar bone grafting.
Davidson, Elizabeth J; Martin, Benson B; Rieger, Randall H; Parente, Eric J
2010-12-01
To (1) assess upper airway function by videoendoscopy in horses performing poorly after laryngoplasty and (2) establish whether dynamic collapse of the left arytenoid can be predicted by the degree of resting postsurgical abduction. Case series. Horses that had left laryngoplasty (n=45). Medical records (June 1993-December 2007) of horses evaluated for abnormal respiratory noise and/or poor performance after laryngoplasty were reviewed. Horses with video recordings of resting and exercising upper airway endoscopy were included and postsurgical abduction categorized. Horses with immediate postoperative endoscopy recordings were also evaluated and postsurgical abduction categorized. Relationships between resting postsurgical abduction and historical information with exercising endoscopic findings were examined. Dynamic collapse of the left arytenoid cartilage was probable in horses with no postsurgical abduction and could not be predicted in horses with grade 3 or 4 postsurgical abduction. Respiratory noise was associated with upper airway obstruction but was not specific for arytenoid collapse. Most horses with a left vocal fold had billowing of the fold during exercise. Other forms of dynamic collapse involved the right vocal fold, aryepiglottic folds, corniculate process of left arytenoid cartilage, dorsal displacement of soft palate, and pharyngeal collapse. Complex obstructions were observed in most examinations and in all horses with exercising collapse of the left arytenoid cartilage. There was no relationship between exercising collapse of the left arytenoid cartilage and grade 3 or 4 postsurgical abduction but was likely in horses with no abduction. © Copyright 2010 by The American College of Veterinary Surgeons.
Geological constraints of a structural model of sector collapse at Stromboli volcano, Italy
NASA Astrophysics Data System (ADS)
Vezzoli, L.; Corazzato, C.
2016-09-01
This study is focused on the reconstruction of the structure and dynamics of the first lateral collapse that occurred at Stromboli during the Holocene, which represents the structure inherited by all the following collapses that formed the present Sciara del Fuoco depression. The first lateral collapse of Stromboli occurred at the end of the Vancori volcano activity, at about 13 ka ago. The Neostromboli lava cone grew within this collapse amphitheater. Based on a comprehensive geologic and structural analysis of both Vancori and Neostromboli products, we propose an innovative interpretation of the sliding surface. Once considered to be a homogeneous landslide along a deep-seated sliding surface, we demonstrate that the Upper Vancori failure was accommodated by a more complex deformation regime comprising an upper (proximal) domain of tilted megablocks (toreva) and a lower (distal) domain of fragmental landslide transport and deposition.
Postoperative respiratory muscle dysfunction: pathophysiology and preventive strategies.
Sasaki, Nobuo; Meyer, Matthew J; Eikermann, Matthias
2013-04-01
Postoperative pulmonary complications are responsible for significant increases in hospital cost as well as patient morbidity and mortality; respiratory muscle dysfunction represents a contributing factor. Upper airway dilator muscles functionally resist the upper airway collapsing forces created by the respiratory pump muscles. Standard perioperative medications (anesthetics, sedatives, opioids, and neuromuscular blocking agents), interventions (patient positioning, mechanical ventilation, and surgical trauma), and diseases (lung hyperinflation, obesity, and obstructive sleep apnea) have differential effects on the respiratory muscle subgroups. These effects on the upper airway dilators and respiratory pump muscles impair their coordination and function and can result in respiratory failure. Perioperative management strategies can help decrease the incidence of postoperative respiratory muscle dysfunction. Such strategies include minimally invasive procedures rather than open surgery, early and optimal mobilizing of respiratory muscles while on mechanical ventilation, judicious use of respiratory depressant anesthetics and neuromuscular blocking agents, and noninvasive ventilation when possible.
Caravaglios, Giuseppe; Muscoso, Emma Gabriella; Di Maria, Giulia; Costanzo, Erminio
2015-03-01
There are several evidences indicating that an impairment in attention-executive functions is present in prodromal Alzheimer's disease and predict future global cognitive decline. In particular, the issue of temporal orienting of attention in patients with mild cognitive impairment (MCI) due to Alzheimer's disease has been overlooked. The present research aimed to explore whether subtle deficits of cortical activation are present in these patients early in the course of the disease. We studied the upper-alpha event-related synchronization/desynchronization phenomenon during a paradigm of temporal orientation of attention. MCI patients (n = 27) and healthy elderly controls (n = 15) performed a task in which periodically omitted tones had to be predicted and their virtual onset time had to be marked by pressing a button. Single-trial responses were measured, respectively, before and after the motor response. Then, upper-alpha responses were compared to upper-alpha power during eyes-closed resting state. The time course of the task was characterized by two different behavioral conditions: (1) a pre-event epoch, in which the subject awaited the virtual onset of the omitted tone, (2) a post-event epoch (after button pressing), in which the subject was in a post-motor response condition. The principal findings are: (1) during the waiting epoch, only healthy elderly had an upper-alpha ERD at the level of both temporal and posterior brain regions; (2) during the post-motor epoch, the aMCI patients had a weaker upper-alpha ERS on prefrontal regions; (3) only healthy elderly showed a laterality effect: (a) during the waiting epoch, the upper-alpha ERD was greater at the level of the right posterior-temporal lead; during the post-motor epoch, the upper alpha ERS was greater on the left prefrontal lead. The relevance of these findings is that the weaker upper-alpha response observed in aMCI patients is evident even if the accuracy of the behavioral performance (i.e., button pressing) is still spared. This abnormal upper-alpha response might represent an early biomarker of the attention-executive network impairment in MCI due to Alzheimer's disease.
Patel, Jigna; Qiu, Qinyin; Yarossi, Mathew; Merians, Alma; Massood, Supriya; Tunik, Eugene; Adamovich, Sergei; Fluet, Gerard
2017-07-01
Explore the potential benefits of using priming methods prior to an active hand task in the acute phase post-stroke in persons with severe upper extremity hemiparesis. Five individuals were trained using priming techniques including virtual reality (VR) based visual mirror feedback and contralaterally controlled passive movement strategies prior to training with an active pinch force modulation task. Clinical, kinetic, and neurophysiological measurements were taken pre and post the training period. Clinical measures were taken at six months post training. The two priming simulations and active training were well tolerated early after stroke. Priming effects were suggested by increased maximal pinch force immediately after visual and movement based priming. Despite having no clinically observable movement distally, the subjects were able to volitionally coordinate isometric force and muscle activity (EMG) in a pinch tracing task. The Root Mean Square Error (RMSE) of force during the pinch trace task gradually decreased over the training period suggesting learning may have occurred. Changes in motor cortical neurophysiology were seen in the unaffected hemisphere using Transcranial Magnetic Stimulation (TMS) mapping. Significant improvements in motor recovery as measured by the Action Research Arm Test (ARAT) and the Upper Extremity Fugl Meyer Assessment (UEFMA) were demonstrated at six months post training by three of the five subjects. This study suggests that an early hand-based intervention using visual and movement based priming activities and a scaled motor task allows participation by persons without the motor control required for traditionally presented rehabilitation and testing. Implications for Rehabilitation Rehabilitation of individuals with severely paretic upper extremities after stroke is challenging due to limited movement capacity and few options for therapeutic training. Long-term functional recovery of the arm after stroke depends on early return of active hand control, establishing a need for acute training methods focused distally. This study demonstrates the feasibility of an early hand-based intervention using virtual reality based priming and scaled motor activities which can allow for participation by persons without the motor control required for traditionally presented rehabilitation and testing.
Impact of early applied upper limb stimulation: the EXPLICIT-stroke programme design.
Kwakkel, Gert; Meskers, Carel G M; van Wegen, Erwin E; Lankhorst, Guus J; Geurts, Alexander C H; van Kuijk, Annet A; Lindeman, Eline; Visser-Meily, Anne; de Vlugt, Erwin; Arendzen, J Hans
2008-12-17
Main claims of the literature are that functional recovery of the paretic upper limb is mainly defined within the first month post stroke and that rehabilitation services should preferably be applied intensively and in a task-oriented way within this particular time window. EXplaining PLastICITy after stroke (acronym EXPLICIT-stroke) aims to explore the underlying mechanisms of post stroke upper limb recovery. Two randomized single blinded trials form the core of the programme, investigating the effects of early modified Constraint-Induced Movement Therapy (modified CIMT) and EMG-triggered Neuro-Muscular Stimulation (EMG-NMS) in patients with respectively a favourable or poor probability for recovery of dexterity. 180 participants suffering from an acute, first-ever ischemic stroke will be recruited. Functional prognosis at the end of the first week post stroke is used to stratify patient into a poor prognosis group for upper limb recovery (N = 120, A2 project) and a group with a favourable prognosis (N = 60, A1 project). Both groups will be randomized to an experimental arm receiving respectively modified CIMT (favourable prognosis) or EMG-NMS (poor prognosis) for 3 weeks or to a control arm receiving usual care. Primary outcome variable will be the Action Research Arm Test (ARAT), assessed at 1,2,3,4,5, 8, 12 and 26 weeks post stroke. To study the impact of modified CIMT or EMG-NMS on stroke recovery mechanisms i.e. neuroplasticity, compensatory movements and upper limb neuromechanics, 60 patients randomly selected from projects A1 and A2 will undergo TMS, kinematical and haptic robotic measurements within a repeated measurement design. Additionally, 30 patients from the A1 project will undergo fMRI at baseline, 5 and 26 weeks post stroke. EXPLICIT stroke is a 5 year translational research programme which main aim is to investigate the effects of early applied intensive intervention for regaining dexterity and to explore the underlying mechanisms that are involved in regaining upper limb function after stroke. EXPLICIT-stroke will provide an answer to the key question whether therapy induced improvements are due to either a reduction of basic motor impairment by neural repair i.e. restitution of function and/or the use of behavioural compensation strategies i.e. substitution of function.
NASA Astrophysics Data System (ADS)
Edgar, C. J.; Cas, R. A. F.; Olin, P. H.; Wolff, J. A.; Martí, J.; Simmons, J. M.
2017-10-01
The 312 ka Fasnia eruption from the Las Cañadas Caldera on Tenerife, Canary Islands, Spain, produced a complex sequence of twenty-two intercalated units, including 7 pumice fall, 7 ignimbrite and 8 ash surge and fall deposits that define two distinct eruption sequences (Lower and Upper Fasnia sequences). The fallout units themselves are internally complex, reflecting waxing and waning of the eruption column, while many of the ignimbrites reflect multiple intra-plinian partial column collapse events associated with the injection of lithic clasts into the eruption column. The Lower and Upper Fasnia eruption phases were each terminated by caldera collapse and complete column collapse events. Probable blockage of the conduit and vent system during Lower Fasnia caldera collapse event briefly terminated the eruption, resulting in a short-lived period of erosion and sedimentation prior to the onset of the Upper Fasnia phase. The transition to the Upper Fasnia eruption phase coincided with the eruption of more geochemically homogeneous pyroclasts. In total, 62 km3 of tephra were erupted, including 49 km3 of juvenile clasts and > 12 km3 of lithic clasts. The DRE volume of magma erupted was 13 km3 (Lower Fasnia > 5 km3, Upper Fasnia > 8 km3), two thirds of which ( 9-10 km3) was deposited purely by fallout. The Fasnia Member is one of the most complex plinian sequences known.
Supplemental Carbon Dioxide Stabilizes the Upper Airway in Volunteers Anesthetized with Propofol.
Ruscic, Katarina Jennifer; Bøgh Stokholm, Janne; Patlak, Johann; Deng, Hao; Simons, Jeroen Cedric Peter; Houle, Timothy; Peters, Jürgen; Eikermann, Matthias
2018-05-10
Propofol impairs upper airway dilator muscle tone and increases upper airway collapsibility. Preclinical studies show that carbon dioxide decreases propofol-mediated respiratory depression. We studied whether elevation of end-tidal carbon dioxide (PETCO2) via carbon dioxide insufflation reverses the airway collapsibility (primary hypothesis) and impaired genioglossus muscle electromyogram that accompany propofol anesthesia. We present a prespecified, secondary analysis of previously published experiments in 12 volunteers breathing via a high-flow respiratory circuit used to control upper airway pressure under propofol anesthesia at two levels, with the deep level titrated to suppression of motor response. Ventilation, mask pressure, negative pharyngeal pressure, upper airway closing pressure, genioglossus electromyogram, bispectral index, and change in end-expiratory lung volume were measured as a function of elevation of PETCO2 above baseline and depth of propofol anesthesia. PETCO2 augmentation dose-dependently lowered upper airway closing pressure with a decrease of 3.1 cm H2O (95% CI, 2.2 to 3.9; P < 0.001) under deep anesthesia, indicating improved upper airway stability. In parallel, the phasic genioglossus electromyogram increased by 28% (23 to 34; P < 0.001). We found that genioglossus electromyogram activity was a significant modifier of the effect of PETCO2 elevation on closing pressure (P = 0.005 for interaction term). Upper airway collapsibility induced by propofol anesthesia can be reversed in a dose-dependent manner by insufflation of supplemental carbon dioxide. This effect is at least partly mediated by increased genioglossus muscle activity.
Gas clump formation via thermal instability in high-redshift dwarf galaxy mergers
NASA Astrophysics Data System (ADS)
Arata, Shohei; Yajima, Hidenobu; Nagamine, Kentaro
2018-04-01
Star formation in high-redshift dwarf galaxies is a key to understand early galaxy evolution in the early Universe. Using the three-dimensional hydrodynamics code GIZMO, we study the formation mechanism of cold, high-density gas clouds in interacting dwarf galaxies with halo masses of ˜3 × 107 M⊙, which are likely to be the formation sites of early star clusters. Our simulations can resolve both the structure of interstellar medium on small scales of ≲ 0.1 pc and the galactic disc simultaneously. We find that the cold gas clouds form in the post-shock region via thermal instability due to metal-line cooling, when the cooling time is shorter than the galactic dynamical time. The mass function of cold clouds shows almost a power-law initially with an upper limit of thermally unstable scale. We find that some clouds merge into more massive ones with ≳104 M⊙ within ˜ 2 Myr. Only the massive cold clouds with ≳ 103 M⊙ can keep collapsing due to gravitational instability, resulting in the formation of star clusters. We find that the clump formation is more efficient in the prograde-prograde merger than the prograde-retrograde case due to the difference in the degree of shear flow. In addition, we investigate the dependence of cloud mass function on metallicity and H2 abundance, and show that the cases with low metallicities (≲10-2 Z⊙) or high H2 abundance (≳10-3) cannot form massive cold clouds with ≳103 M⊙.
Assessment of upper airway mechanics during sleep.
Farré, Ramon; Montserrat, Josep M; Navajas, Daniel
2008-11-30
Obstructive sleep apnea, which is the most prevalent sleep breathing disorder, is characterized by recurrent episodes of upper airway collapse and reopening. However, the mechanical properties of the upper airway are not directly measured in routine polysomnography because only qualitative sensors (thermistors for flow and thoraco-abdominal bands for pressure) are used. This review focuses on two techniques that quantify upper airway obstruction during sleep. A Starling model of collapsible conduit allows us to interpret the mechanics of the upper airway by means of two parameters: the critical pressure (Pcrit) and the upstream resistance (Rup). A simple technique to measure Pcrit and Rup involves the application of different levels of continuous positive airway pressure (CPAP) during sleep. The forced oscillation technique is another non-invasive procedure for quantifying upper airway impedance during the breathing cycle in sleep studies. The latest developments in these two methods allow them to be easily applied on a routine basis in order to more fully characterize upper airway mechanics in patients with sleep breathing disorders.
Visouli, Aikaterini N.; Zarogoulidis, Konstantinos; Kougioumtzi, Ioanna; Huang, Haidong; Li, Qiang; Dryllis, Georgios; Kioumis, Ioannis; Pitsiou, Georgia; Machairiotis, Nikolaos; Katsikogiannis, Nikolaos; Papaiwannou, Antonis; Lampaki, Sofia; Zaric, Bojan; Branislav, Perin; Porpodis, Konstantinos
2014-01-01
Catamenial pneumothorax (CP) is the most common form of thoracic endometriosis syndrome, which also includes catamenial hemothorax, catamenial hemoptysis, catamenial hemopneumothorax and endometriosis lung nodules, as well as some exceptional presentations. Usually onset of lung collapse is less than 72 hours after menstruation. Most commonly occurs in women aged 30-40 years, but has been diagnosed in young girls as early as 10 years of age and post menopausal women (exclusively in women of menstrual age) most with a history of pelvic endometriosis. Diagnosis can be hinted by high recurrence rates of lung collapse in a woman of reproductive age with endometriosis. Moreover; CA-125 is elevated. Video-assisted thoracoscopy or medical thoracoscopy is used for confirmation. In our current work we will present all aspects of CP from diagnosis to treatment. PMID:25337402
NASA Astrophysics Data System (ADS)
John, D. A.; Breit, G. N.; Sisson, T. W.; Vallance, J. W.; Rye, R. O.
2005-12-01
Mount Rainier is the result of episodic stages of edifice growth during periods of high eruptive activity and edifice destruction during periods of relative magmatic quiescence over the past 500 kyr. Edifice destruction occurred both by slow erosion and by catastrophic collapses, some of which were strongly influenced by hydrothermal alteration. Several large-volume Holocene debris-flow deposits contain abundant clasts of hydrothermally altered rocks, most notably the 4-km3 clay-rich Osceola Mudflow which formed by collapse of the northeast side and upper 1000+ m of the edifice about 5600 ya and flowed >120 km downstream into Puget Sound. Mineral assemblages and stable isotope data of hydrothermal alteration products in Holocene debris-flow deposits indicate formation in distinct hydrothermal environments, including magmatic-hydrothermal, steam-heated (including a large fumarolic component), magmatic steam (including a possible fumarolic component), and supergene. The Osceola Mudflow and phreatic components of coeval tephras contain the highest-temperature and inferred most deeply formed alteration minerals; assemblages include magmatic-hydrothermal quartz-alunite, quartz-topaz, quartz-pyrophyllite and quartz-illite (all +pyrite), in addition to steam-heated opal-alunite-kaolinite and abundant smectite-pyrite. In contrast, the Paradise lahar, which formed by a collapse of the surficial upper south side of the edifice, contains only steam-heated assemblages including those formed largely above the water table from condensation of fumarolic vapor (opal-alunite-jarosite). Younger debris-flow deposits on the west side of the volcano (Round Pass lahar and Electron Mudflow) contain only smectite-pyrite alteration, whereas an early 20th century rock avalanche on Tahoma Glacier also contains magmatic-hydrothermal alteration that is exposed in the avalanche headwall of Sunset Amphitheater. Mineralogy and isotopic composition of the alteration phases, geologic and geophysical data, as well as analog fossil hydrothermal systems in volcanoes elsewhere, constrain hydrothermal alteration geometry on the pre-Osceola-collapse edifice of Mount Rainier. Relatively narrow zones of acid magmatic-hydrothermal alteration in the central core of the volcano grade to more widely distributed smectite-pyrite alteration farther out on the upper flanks, capped by steam-heated alteration with a large component of alteration resulting from condensation of fumarolic vapor above the water table. Alteration was polygenetic in zones formed episodically, and was strongly controlled by fluxes of heat and magmatic fluid and by local permeability.
How Hives Collapse: Allee Effects, Ecological Resilience, and the Honey Bee
Dennis, Brian; Kemp, William P.
2016-01-01
We construct a mathematical model to quantify the loss of resilience in collapsing honey bee colonies due to the presence of a strong Allee effect. In the model, recruitment and mortality of adult bees have substantial social components, with recruitment enhanced and mortality reduced by additional adult bee numbers. The result is an Allee effect, a net per-individual rate of hive increase that increases as a function of adult bee numbers. The Allee effect creates a critical minimum size in adult bee numbers, below which mortality is greater than recruitment, with ensuing loss of viability of the hive. Under ordinary and favorable environmental circumstances, the critical size is low, and hives remain large, sending off viably-sized swarms (naturally or through beekeeping management) when hive numbers approach an upper stable equilibrium size (carrying capacity). However, both the lower critical size and the upper stable size depend on many parameters related to demographic rates and their enhancement by bee sociality. Any environmental factors that increase mortality, decrease recruitment, or interfere with the social moderation of these rates has the effect of exacerbating the Allee effect by increasing the lower critical size and substantially decreasing the upper stable size. As well, the basin of attraction to the upper stable size, defined by the model potential function, becomes narrower and shallower, indicating the loss of resilience as the hive becomes subjected to increased risk of falling below the critical size. Environmental effects of greater severity can cause the two equilibria to merge and the basin of attraction to the upper stable size to disappear, resulting in collapse of the hive from any initial size. The model suggests that multiple proximate causes, among them pesticides, mites, pathogens, and climate change, working singly or in combinations, could trigger hive collapse. PMID:26910061
NASA Astrophysics Data System (ADS)
Boulton, Chris A.; Allison, Lesley C.; Lenton, Timothy M.
2014-12-01
The Atlantic Meridional Overturning Circulation (AMOC) exhibits two stable states in models of varying complexity. Shifts between alternative AMOC states are thought to have played a role in past abrupt climate changes, but the proximity of the climate system to a threshold for future AMOC collapse is unknown. Generic early warning signals of critical slowing down before AMOC collapse have been found in climate models of low and intermediate complexity. Here we show that early warning signals of AMOC collapse are present in a fully coupled atmosphere-ocean general circulation model, subject to a freshwater hosing experiment. The statistical significance of signals of increasing lag-1 autocorrelation and variance vary with latitude. They give up to 250 years warning before AMOC collapse, after ~550 years of monitoring. Future work is needed to clarify suggested dynamical mechanisms driving critical slowing down as the AMOC collapse is approached.
Boulton, Chris A.; Allison, Lesley C.; Lenton, Timothy M.
2014-01-01
The Atlantic Meridional Overturning Circulation (AMOC) exhibits two stable states in models of varying complexity. Shifts between alternative AMOC states are thought to have played a role in past abrupt climate changes, but the proximity of the climate system to a threshold for future AMOC collapse is unknown. Generic early warning signals of critical slowing down before AMOC collapse have been found in climate models of low and intermediate complexity. Here we show that early warning signals of AMOC collapse are present in a fully coupled atmosphere-ocean general circulation model, subject to a freshwater hosing experiment. The statistical significance of signals of increasing lag-1 autocorrelation and variance vary with latitude. They give up to 250 years warning before AMOC collapse, after ~550 years of monitoring. Future work is needed to clarify suggested dynamical mechanisms driving critical slowing down as the AMOC collapse is approached. PMID:25482065
Boulton, Chris A; Allison, Lesley C; Lenton, Timothy M
2014-12-08
The Atlantic Meridional Overturning Circulation (AMOC) exhibits two stable states in models of varying complexity. Shifts between alternative AMOC states are thought to have played a role in past abrupt climate changes, but the proximity of the climate system to a threshold for future AMOC collapse is unknown. Generic early warning signals of critical slowing down before AMOC collapse have been found in climate models of low and intermediate complexity. Here we show that early warning signals of AMOC collapse are present in a fully coupled atmosphere-ocean general circulation model, subject to a freshwater hosing experiment. The statistical significance of signals of increasing lag-1 autocorrelation and variance vary with latitude. They give up to 250 years warning before AMOC collapse, after ~550 years of monitoring. Future work is needed to clarify suggested dynamical mechanisms driving critical slowing down as the AMOC collapse is approached.
Ma, Junqiang; Ma, Yonglie; Dong, Bin; Bandet, Mischa V; Shuaib, Ashfaq; Winship, Ian R
2017-08-01
Collateral circulation is a key variable determining prognosis and response to recanalization therapy during acute ischemic stroke. Remote ischemic perconditioning (RIPerC) involves inducing peripheral ischemia (typically in the limbs) during stroke and may reduce perfusion deficits and brain damage due to cerebral ischemia. In this study, we directly investigated pial collateral flow augmentation due to RIPerC during distal middle cerebral artery occlusion (MCAo) in rats. Blood flow through pial collaterals between the anterior cerebral artery (ACA) and the MCA was assessed in male Sprague Dawley rats using in vivo laser speckle contrast imaging (LSCI) and two photon laser scanning microscopy (TPLSM) during distal MCAo. LSCI and TPLSM revealed that RIPerC augmented collateral flow into distal MCA segments. Notably, while control rats exhibited an initial dilation followed by a progressive narrowing of pial arterioles 60 to 150-min post-MCAo (constricting to 80-90% of post-MCAo peak diameter), this constriction was prevented or reversed by RIPerC (such that vessel diameters increased to 105-110% of post-MCAo, pre-RIPerC diameter). RIPerC significantly reduced early ischemic damage measured 6 h after stroke onset. Thus, prevention of collateral collapse via RIPerC is neuroprotective and may facilitate other protective or recanalization therapies by improving blood flow in penumbral tissue.
InSAR Measurement of Precursor and Post-Collapse Sinkhole Subsidence
NASA Astrophysics Data System (ADS)
Holley, Rachel; McCormack, Harry; Larkin, Hayley; Wooster, Michael; Thomas, Adam
2016-08-01
Sinkholes occur across the world, often posing an obvious hazard to communities, infrastructure and the environment. Regions prone to sinkhole formation can often be identified; however prediction of exact sinkhole locations and occurrences is exceedingly difficult. This case study from Wink, in the Permian Basin of Texas, demonstrates how InSAR can measure both precursor and post-collapse deformation associated with sinkholes. ERS, ALOS PALSAR and Sentinel-1A datasets are used to show precursor signals at least nine years before sinkhole formation, and post-collapse effects continuing over several decades. The rate of deformation is variable, but reaches many tens of centimetres per year during some periods.
Dynamics of sonoluminescing bubbles within a liquid hammer device.
Urteaga, Raúl; García-Martínez, Pablo Luis; Bonetto, Fabián J
2009-01-01
We studied the dynamics of a single sonoluminescing bubble (SBSL) in a liquid hammer device. In particular, we investigated the phosphoric acid-xenon system, in which pulses up to four orders of magnitude brighter than SBSL in water systems (about 10;{12} photons per pulse) have been previously reported [Chakravarty, Phys. Rev. E 69, 066317 (2004)]. We used stroboscopic photography and a Mie scattering technique in order to measure the radius evolution of the bubbles. Under adequate conditions we may position a bubble at the bottom of the tube (cavity) and a second bubble trapped at the middle of the tube (upper bubble). During its collapse, the cavity produces the compression of the liquid column. This compression drives impulsively the dynamics of the upper bubble. Our measurements reveal that the observed light emissions produced by the upper bubble are generated at its second collapse. We employed a simple numerical model to investigate the conditions that occur during the upper bubble collapse. We found good agreement between numerical and experimental values for the light intensity (fluence) and light pulse widths. Results from the model show that the light emission is increased mainly due to an increase in noble gas ambient radius and not because the maximum temperature increases. Even for the brightest pulses obtained ( 2x10;{13} photons, about 20W of peak power) the maximum temperatures computed for the upper bubble are always lower than 20000K .
NASA Astrophysics Data System (ADS)
Abbott, B. P.; Abbott, R.; Abbott, T. D.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Afrough, M.; Agarwal, B.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allen, G.; Allocca, A.; Altin, P. A.; Amato, A.; Ananyeva, A.; Anderson, S. B.; Anderson, W. G.; Angelova, S. V.; Antier, S.; Appert, S.; Arai, K.; Araya, M. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Atallah, D. V.; Aufmuth, P.; Aulbert, C.; AultONeal, K.; Austin, C.; Avila-Alvarez, A.; Babak, S.; Bacon, P.; Bader, M. K. M.; Bae, S.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Banagiri, S.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barkett, K.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Bawaj, M.; Bayley, J. C.; Bazzan, M.; Bécsy, B.; Beer, C.; Bejger, M.; Belahcene, I.; Bell, A. S.; Berger, B. K.; Bergmann, G.; Bernuzzi, S.; Bero, J. J.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Billman, C. R.; Birch, J.; Birney, R.; Birnholtz, O.; Biscans, S.; Biscoveanu, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blackman, J.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bode, N.; Boer, M.; Bogaert, G.; Bohe, A.; Bondu, F.; Bonilla, E.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bossie, K.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Broida, J. E.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brunett, S.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cabero, M.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T. A.; Calloni, E.; Camp, J. B.; Canepa, M.; Canizares, P.; Cannon, K. C.; Cao, H.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Carney, M. F.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerdá-Durán, P.; Cerretani, G.; Cesarini, E.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chase, E.; Chassande-Mottin, E.; Chatterjee, D.; Cheeseboro, B. D.; Chen, H. Y.; Chen, X.; Chen, Y.; Cheng, H.-P.; Chia, H.; Chincarini, A.; Chiummo, A.; Chmiel, T.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, A. J. K.; Chua, S.; Chung, A. K. W.; Chung, S.; Ciani, G.; Ciolfi, R.; Cirelli, C. E.; Cirone, A.; Clara, F.; Clark, J. A.; Clearwater, P.; Cleva, F.; Cocchieri, C.; Coccia, E.; Cohadon, P.-F.; Cohen, D.; Colla, A.; Collette, C. G.; Cominsky, L. R.; Constancio, M., Jr.; Conti, L.; Cooper, S. J.; Corban, P.; Corbitt, T. R.; Cordero-Carrión, I.; Corley, K. R.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Covas, P. B.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Creighton, J. D. E.; Creighton, T. D.; Cripe, J.; Crowder, S. G.; Cullen, T. J.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Dálya, G.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Dasgupta, A.; Da Silva Costa, C. F.; Dattilo, V.; Dave, I.; Davier, M.; Davis, D.; Daw, E. J.; Day, B.; De, S.; DeBra, D.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Demos, N.; Denker, T.; Dent, T.; De Pietri, R.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; De Rossi, C.; DeSalvo, R.; de Varona, O.; Devenson, J.; Dhurandhar, S.; Díaz, M. C.; Dietrich, T.; Di Fiore, L.; Di Giovanni, M.; Di Girolamo, T.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Renzo, F.; Doctor, Z.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Dorrington, I.; Douglas, R.; Dovale Álvarez, M.; Downes, T. P.; Drago, M.; Dreissigacker, C.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dupej, P.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Eisenstein, R. A.; Essick, R. C.; Estevez, D.; Etienne, Z. B.; Etzel, T.; Evans, M.; Evans, T. M.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Farinon, S.; Farr, B.; Farr, W. M.; Fauchon-Jones, E. J.; Favata, M.; Fays, M.; Fee, C.; Fehrmann, H.; Feicht, J.; Fejer, M. M.; Fernandez-Galiana, A.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Finstad, D.; Fiori, I.; Fiorucci, D.; Fishbach, M.; Fisher, R. P.; Fitz-Axen, M.; Flaminio, R.; Fletcher, M.; Flynn, E.; Fong, H.; Font, J. A.; Forsyth, P. W. F.; Forsyth, S. S.; Fournier, J.-D.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fries, E. M.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H.; Gadre, B. U.; Gaebel, S. M.; Gair, J. R.; Gammaitoni, L.; Ganija, M. R.; Gaonkar, S. G.; Garcia-Quiros, C.; Garufi, F.; Gateley, B.; Gaudio, S.; Gaur, G.; Gayathri, V.; Gehrels, N.; Gemme, G.; Genin, E.; Gennai, A.; George, D.; George, J.; Gergely, L.; Germain, V.; Ghonge, S.; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glover, L.; Goetz, E.; Goetz, R.; Gomes, S.; Goncharov, B.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Grado, A.; Graef, C.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Gretarsson, E. M.; Groot, P.; Grote, H.; Grunewald, S.; Gruning, P.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Halim, O.; Hall, B. R.; Hall, E. D.; Hamilton, E. Z.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hannuksela, O. A.; Hanson, J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Haster, C.-J.; Haughian, K.; Healy, J.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hinderer, T.; Hoak, D.; Hofman, D.; Holt, K.; Holz, D. E.; Hopkins, P.; Horst, C.; Hough, J.; Houston, E. A.; Howell, E. J.; Hreibi, A.; Hu, Y. M.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Indik, N.; Inta, R.; Intini, G.; Isa, H. N.; Isac, J.-M.; Isi, M.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Junker, J.; Kalaghatgi, C. V.; Kalogera, V.; Kamai, B.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Kapadia, S. J.; Karki, S.; Karvinen, K. S.; Kasprzack, M.; Kastaun, W.; Katolik, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kawabe, K.; Kéfélian, F.; Keitel, D.; Kemball, A. J.; Kennedy, R.; Kent, C.; Key, J. S.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, Chunglee; Kim, J. C.; Kim, K.; Kim, W.; Kim, W. S.; Kim, Y.-M.; Kimbrell, S. J.; King, E. J.; King, P. J.; Kinley-Hanlon, M.; Kirchhoff, R.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Knowles, T. D.; Koch, P.; Koehlenbeck, S. M.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Krämer, C.; Kringel, V.; Krishnan, B.; Królak, A.; Kuehn, G.; Kumar, P.; Kumar, R.; Kumar, S.; Kuo, L.; Kutynia, A.; Kwang, S.; Lackey, B. D.; Lai, K. H.; Landry, M.; Lang, R. N.; Lange, J.; Lantz, B.; Lanza, R. K.; Lartaux-Vollard, A.; Lasky, P. D.; Laxen, M.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, H. W.; Lee, K.; Lehmann, J.; Lenon, A.; Leonardi, M.; Leroy, N.; Letendre, N.; Levin, Y.; Li, T. G. F.; Linker, S. D.; Liu, J.; Lo, R. K. L.; Lockerbie, N. A.; London, L. T.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lousto, C. O.; Lovelace, G.; Lück, H.; Lumaca, D.; Lundgren, A. P.; Lynch, R.; Ma, Y.; Macas, R.; Macfoy, S.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña Hernandez, I.; Magaña-Sandoval, F.; Magaña Zertuche, L.; Magee, R. M.; Majorana, E.; Maksimovic, I.; Man, N.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markakis, C.; Markosyan, A. S.; Markowitz, A.; Maros, E.; Marquina, A.; Martelli, F.; Martellini, L.; Martin, I. W.; Martin, R. M.; Martynov, D. V.; Mason, K.; Massera, E.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Mastrogiovanni, S.; Matas, A.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McCuller, L.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McNeill, L.; McRae, T.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Mehmet, M.; Meidam, J.; Mejuto-Villa, E.; Melatos, A.; Mendell, G.; Mercer, R. A.; Merilh, E. L.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Metzdorff, R.; Meyers, P. M.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, A. L.; Miller, B. B.; Miller, J.; Milovich-Goff, M. C.; Minazzoli, O.; Minenkov, Y.; Ming, J.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moffa, D.; Moggi, A.; Mogushi, K.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mours, B.; Mow-Lowry, C. M.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, N.; Mullavey, A.; Munch, J.; Muñiz, E. A.; Muratore, M.; Murray, P. G.; Napier, K.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Neilson, J.; Nelemans, G.; Nelson, T. J. N.; Nery, M.; Neunzert, A.; Nevin, L.; Newport, J. M.; Newton, G.; Ng, K. K. Y.; Nguyen, T. T.; Nichols, D.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Noack, A.; Nocera, F.; Nolting, D.; North, C.; Nuttall, L. K.; Oberling, J.; O'Dea, G. D.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Okada, M. A.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; Ormiston, R.; Ortega, L. F.; O'Shaughnessy, R.; Ossokine, S.; Ottaway, D. J.; Overmier, H.; Owen, B. J.; Pace, A. E.; Page, J.; Page, M. A.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, Howard; Pan, Huang-Wei; Pang, B.; Pang, P. T. H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Parida, A.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patil, M.; Patricelli, B.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Perez, C. J.; Perreca, A.; Perri, L. M.; Pfeiffer, H. P.; Phelps, M.; Phukon, K. S.; Piccinni, O. J.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pirello, M.; Pitkin, M.; Poe, M.; Poggiani, R.; Popolizio, P.; Porter, E. K.; Post, A.; Powell, J.; Prasad, J.; Pratt, J. W. W.; Pratten, G.; Predoi, V.; Prestegard, T.; Prijatelj, M.; Principe, M.; Privitera, S.; Prodi, G. A.; Prokhorov, L. G.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rajan, C.; Rajbhandari, B.; Rakhmanov, M.; Ramirez, K. E.; Ramos-Buades, A.; Rapagnani, P.; Raymond, V.; Razzano, M.; Read, J.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Ren, W.; Reyes, S. D.; Ricci, F.; Ricker, P. M.; Rieger, S.; Riles, K.; Rizzo, M.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, R.; Romel, C. L.; Romie, J. H.; Rosińska, D.; Ross, M. P.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Rutins, G.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Sakellariadou, M.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sampson, L. M.; Sanchez, E. J.; Sanchez, L. E.; Sanchis-Gual, N.; Sandberg, V.; Sanders, J. R.; Sarin, N.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O.; Savage, R. L.; Sawadsky, A.; Schale, P.; Scheel, M.; Scheuer, J.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schulte, B. W.; Schutz, B. F.; Schwalbe, S. G.; Scott, J.; Scott, S. M.; Seidel, E.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Shaddock, D. A.; Shaffer, T. J.; Shah, A. A.; Shahriar, M. S.; Shaner, M. B.; Shao, L.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sieniawska, M.; Sigg, D.; Silva, A. D.; Singer, L. P.; Singh, A.; Singhal, A.; Sintes, A. M.; Rana, J.; Slagmolen, B. J. J.; Smith, B.; Smith, J. R.; Smith, R. J. E.; Somala, S.; Son, E. J.; Sonnenberg, J. A.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Sowell, E.; Spencer, A. P.; Srivastava, A. K.; Staats, K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stevenson, S. P.; Stone, R.; Stops, D. J.; Strain, K. A.; Stratta, G.; Strigin, S. E.; Strunk, A.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sunil, S.; Suresh, J.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Tait, S. C.; Talbot, C.; Talukder, D.; Tanner, D. B.; Tápai, M.; Taracchini, A.; Tasson, J. D.; Taylor, J. A.; Taylor, R.; Tewari, S. V.; Theeg, T.; Thies, F.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Toland, K.; Tonelli, M.; Tornasi, Z.; Torres-Forné, A.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trinastic, J.; Tringali, M. C.; Trozzo, L.; Tsang, K. W.; Tse, M.; Tso, R.; Tsukada, L.; Tsuna, D.; Tuyenbayev, D.; Ueno, K.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Varma, V.; Vass, S.; Vasúth, M.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Venugopalan, G.; Verkindt, D.; Vetrano, F.; Viceré, A.; Viets, A. D.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, M.; Walet, R.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, J. Z.; Wang, W. H.; Wang, Y. F.; Ward, R. L.; Warner, J.; Was, M.; Watchi, J.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Wen, L.; Wessel, E. K.; Weßels, P.; Westerweck, J.; Westphal, T.; Wette, K.; Whelan, J. T.; White, D. D.; Whiting, B. F.; Whittle, C.; Wilken, D.; Williams, D.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Woehler, J.; Wofford, J.; Wong, K. W. K.; Worden, J.; Wright, J. L.; Wu, D. S.; Wysocki, D. M.; Xiao, S.; Yamamoto, H.; Yancey, C. C.; Yang, L.; Yap, M. J.; Yazback, M.; Yu, Hang; Yu, Haocun; Yvert, M.; Zadrożny, A.; Zanolin, M.; Zelenova, T.; Zendri, J.-P.; Zevin, M.; Zhang, L.; Zhang, M.; Zhang, T.; Zhang, Y.-H.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, S. J.; Zhu, X. J.; Zimmerman, A. B.; Zucker, M. E.; Zweizig, J.; (LIGO Scientific Collaboration; Virgo Collaboration
2017-12-01
The first observation of a binary neutron star (NS) coalescence by the Advanced LIGO and Advanced Virgo gravitational-wave (GW) detectors offers an unprecedented opportunity to study matter under the most extreme conditions. After such a merger, a compact remnant is left over whose nature depends primarily on the masses of the inspiraling objects and on the equation of state of nuclear matter. This could be either a black hole (BH) or an NS, with the latter being either long-lived or too massive for stability implying delayed collapse to a BH. Here, we present a search for GWs from the remnant of the binary NS merger GW170817 using data from Advanced LIGO and Advanced Virgo. We search for short- (≲1 s) and intermediate-duration (≲500 s) signals, which include GW emission from a hypermassive NS or supramassive NS, respectively. We find no signal from the post-merger remnant. Our derived strain upper limits are more than an order of magnitude larger than those predicted by most models. For short signals, our best upper limit on the root sum square of the GW strain emitted from 1-4 kHz is {h}{rss}50 % =2.1× {10}-22 {{Hz}}-1/2 at 50% detection efficiency. For intermediate-duration signals, our best upper limit at 50% detection efficiency is {h}{rss}50 % =8.4× {10}-22 {{Hz}}-1/2 for a millisecond magnetar model, and {h}{rss}50 % =5.9× {10}-22 {{Hz}}-1/2 for a bar-mode model. These results indicate that post-merger emission from a similar event may be detectable when advanced detectors reach design sensitivity or with next-generation detectors.
Nelissen, Pieter; White, Richard A S
2012-02-01
To identify combined laryngeal paralysis and collapse in small dogs and describe postoperative outcome after arytenoid lateralization. Case series. Small nonbrachycephalic breed dogs with laryngeal paralysis and collapse (n = 6). Medical records of small breed dogs with airway problems and undergoing laryngeal surgery (January-December 2008) were reviewed. Dogs with combined laryngeal paralysis and laryngeal collapse (LPLC) had arytenoid lateralization. The immediate, 4 week and 6 month postoperative outcomes were described. Direct visual laryngeal exam under a light plane of anesthesia revealed bilateral failure of arytenoid and vocal fold movement and concurrent bilateral medial folding with contact of the cuneiform processes in all dogs. None of the dogs had intra- or immediate postoperative complications after arytenoid lateralization. Two dogs required a 2nd contralateral procedure. Follow-up after 6 months revealed marked improvement in clinical signs related to upper airway obstruction, but all dogs continued to have mild respiratory noise. Concurrent laryngeal paralysis and collapse should be considered as part of the differential diagnosis for small, nonbrachycephalic dogs with upper airway disease. Arytenoid lateralization resulted in improvement of clinical signs related to obstructive airway disease. © Copyright 2011 by The American College of Veterinary Surgeons.
Body size shifts and early warning signals precede the historic collapse of whale stocks.
Clements, Christopher F; Blanchard, Julia L; Nash, Kirsty L; Hindell, Mark A; Ozgul, Arpat
2017-06-22
Predicting population declines is a key challenge in the face of global environmental change. Abundance-based early warning signals have been shown to precede population collapses; however, such signals are sensitive to the low reliability of abundance estimates. Here, using historical data on whales harvested during the 20th century, we demonstrate that early warning signals can be present not only in the abundance data, but also in the more reliable body size data of wild populations. We show that during the period of commercial whaling, the mean body size of caught whales declined dramatically (by up to 4 m over a 70-year period), leading to early warning signals being detectable up to 40 years before the global collapse of whale stocks. Combining abundance and body size data can reduce the length of the time series required to predict collapse, and decrease the chances of false positive early warning signals.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cataneo, Matteo; Rapetti, David; Lombriser, Lucas
We refine the mass and environment dependent spherical collapse model of chameleon f ( R ) gravity by calibrating a phenomenological correction inspired by the parameterized post-Friedmann framework against high-resolution N -body simulations. We employ our method to predict the corresponding modified halo mass function, and provide fitting formulas to calculate the enhancement of the f ( R ) halo abundance with respect to that of General Relativity (GR) within a precision of ∼< 5% from the results obtained in the simulations. Similar accuracy can be achieved for the full f ( R ) mass function on the condition thatmore » the modeling of the reference GR abundance of halos is accurate at the percent level. We use our fits to forecast constraints on the additional scalar degree of freedom of the theory, finding that upper bounds competitive with current Solar System tests are within reach of cluster number count analyses from ongoing and upcoming surveys at much larger scales. Importantly, the flexibility of our method allows also for this to be applied to other scalar-tensor theories characterized by a mass and environment dependent spherical collapse.« less
On the Maximum Mass of Accreting Primordial Supermassive Stars
NASA Astrophysics Data System (ADS)
Woods, T. E.; Heger, Alexander; Whalen, Daniel J.; Haemmerlé, Lionel; Klessen, Ralf S.
2017-06-01
Supermassive primordial stars are suspected to be the progenitors of the most massive quasars at z ˜ 6. Previous studies of such stars were either unable to resolve hydrodynamical timescales or considered stars in isolation, not in the extreme accretion flows in which they actually form. Therefore, they could not self-consistently predict their final masses at collapse, or those of the resulting supermassive black hole seeds, but rather invoked comparison to simple polytropic models. Here, we systematically examine the birth, evolution, and collapse of accreting, non-rotating supermassive stars under accretion rates of 0.01-10 M ⊙ yr-1 using the stellar evolution code Kepler. Our approach includes post-Newtonian corrections to the stellar structure and an adaptive nuclear network and can transition to following the hydrodynamic evolution of supermassive stars after they encounter the general relativistic instability. We find that this instability triggers the collapse of the star at masses of 150,000-330,000 M ⊙ for accretion rates of 0.1-10 M ⊙ yr-1, and that the final mass of the star scales roughly logarithmically with the rate. The structure of the star, and thus its stability against collapse, is sensitive to the treatment of convection and the heat content of the outer accreted envelope. Comparison with other codes suggests differences here may lead to small deviations in the evolutionary state of the star as a function of time, that worsen with accretion rate. Since the general relativistic instability leads to the immediate death of these stars, our models place an upper limit on the masses of the first quasars at birth.
The Universe's Most Extreme Star-forming Galaxies
NASA Astrophysics Data System (ADS)
Casey, Caitlin
2017-06-01
Dusty star-forming galaxies host the most intense stellar nurseries in the Universe. Their unusual characteristics (SFRs=200-2000Msun/yr, Mstar>1010 Msun) pose a unique challenge for cosmological simulations and galaxy formation theory, particularly at early times. Although rare today, they were factors of 1000 times more prevalent at z~2-5, contributing significantly to the buildup of the Universe's stellar mass and the formation of high-mass galaxies. At even earlier times (within 1Gyr post Big Bang) they could have played a pivotal role in enriching the IGM. However, an ongoing debate lingers as to their evolutionary origins at high-redshift, whether or not they are triggered by major mergers of gas-rich disk galaxies, or if they are solitary galaxies continually fed pristine gas from the intergalactic medium. Furthermore, their presence in early protoclusters, only revealed quite recently, pose intriguing questions regarding the collapse of large scale structure. I will discuss some of the latest observational programs dedicated to understanding dust-obscuration in and gas content of the early Universe, their context in the cosmic web, and future long-term observing campaigns that may reveal their relationship to `normal’ galaxies, thus teaching us valuable lessons on the physical mechanisms of galaxy growth and the collapse of large scale structure in an evolving Universe.
Patel, Jigna; Qiu, Qinyin; Yarossi, Mathew; Merians, Alma; Massood, Supriya; Tunik, Eugene; Adamovich, Sergei; Fluet, Gerard
2016-01-01
Purpose Explore the potential benefits of using priming methods prior to an active hand task in the acute phase post-stroke in persons with severe upper extremity hemiparesis. Methods Five individuals were trained using priming techniques including virtual reality (VR) based visual mirror feedback and contralaterally controlled passive movement strategies prior to training with an active pinch force modulation task. Clinical, kinetic, and neurophysiological measurements were taken pre and post the training period. Clinical measures were taken at six months post training. Results The two priming simulations and active training were well tolerated early after stroke. Priming effects were suggested by increased maximal pinch force immediately after visual and movement based priming. Despite having no clinically observable movement distally, the subjects were able to volitionally coordinate isometric force and muscle activity (EMG) in a pinch tracing task. The Root Mean Square Error (RMSE) of force during the pinch trace task gradually decreased over the training period suggesting learning may have occurred. Changes in motor cortical neurophysiology were seen in the unaffected hemisphere using Transcranial Magnetic Stimulation (TMS) mapping. Significant improvements in motor recovery as measured by the Action Research Arm Test (ARAT) and the Upper Extremity Fugl Meyer Assessment (UEFMA) were demonstrated at six months post training by three of the five subjects. Conclusion This study suggests that an early hand-based intervention using visual and movement based priming activities and a scaled motor task allows participation by persons without the motor control required for traditionally presented rehabilitation and testing. PMID:27636200
Prediction of inspiratory flow shapes during sleep with a mathematic model of upper airway forces.
Aittokallio, Tero; Gyllenberg, Mats; Saaresranta, Tarja; Polo, Olli
2003-11-01
To predict the airflow dynamics during sleep using a mathematic model that incorporates a number of static and dynamic upper airway forces, and to compare the numerical results to clinical flow data recorded from patients with sleep-disordered breathing on and off various treatment options. Upper airway performance was modeled in virtual subjects characterized by parameter settings that describe common combinations of risk factors predisposing to upper airway collapse during sleep. The treatments effect were induced by relevant changes of the initial parameter values. Computer simulations at our website (http://www.utu.fi/ml/sovmat/bio/). Risk factors considered in the simulation settings were sex, obesity, pharyngeal collapsibility, and decreased phasic activity of pharyngeal muscles. The effects of weight loss, pharyngeal surgery, nasal continuous positive airway pressure, and respiratory stimulation on the inspiratory flow characteristics were tested with the model. Numerical predictions were investigated by means of 3 measurable inspiratory airflow characteristics: initial slope, total volume, and flow shape. The model was able to reproduce the inspiratory flow shape characteristics that have previously been described in the literature. Simulation results also supported the observations that a multitude of factors underlie the pharyngeal collapse and, therefore, certain medical therapies that are effective in some conditions may prove ineffective in others. A mathematic model integrating the current knowledge of upper airway physiology is able to predict individual treatment responses. The model provides a framework for designing novel and potentially feasible treatment alternatives for sleep-disordered breathing.
Wirth, Klaus J.; Steinmeyer, Klaus; Ruetten, Hartmut
2013-01-01
Study Objectives: Drug treatment for obstructive sleep apnea (OSA) is desirable because at least 30% of patients do not tolerate continuous positive airway pressure (CPAP) treatment. The negative pressure reflex (NPR) involving superficially located mechanoreceptors in the upper airway (UA) is an important mechanism for UA patency inhibitable by topical UA anesthesia (lidocaine). The NPR may serve as a target for pharmacological intervention for a topical treatment of OSA. The objective was to determine the effect of pharmacological augmentation of the NPR on UA collapsibility. Design: We developed a model of UA collapsibility in which application of negative pressures caused UA collapses in spontaneously breathing α-chloralose-urethane anesthetized pigs as indicated by characteristic tracheal pressure and air flow changes. Setting: N/A. Patients or Participants: N/A. Interventions: N/A. Measurements and Results: The potassium channel blocker AVE0118 administered topically to the UA in doses of 1, 3, and 10 mg per nostril sensitized the NPR, shifting the mechanoreceptor response threshold for the genioglossus muscle to more positive pressures (P < 0.001; n = 6 per group) and dose-dependently inhibited UA collapsibility. Ten mg of AVE0118 prevented UA collapses against negative pressures of -150 mbar (P < 0.01) for > 4 h in all pigs, while in control pigs the UA collapsed at -50 mbar or less negative pressures. The effect of AVE0118 was abolished by UA lidocaine anesthesia. Acute intravenous administration of naloxone or acetazolamide was ineffective; paroxetine and mirtazepine were weakly effective and fluoxetine was moderately effective in line with reported clinical efficacy. Conclusion: Topical administration of AVE0118 to the UA is a promising pharmacologic approach for the treatment of OSA. Citation: Wirth KJ; Steinmeyer K; Ruetten H. Sensitization of upper airway mechanoreceptors as a new pharmacologic principle to treat obstructive sleep apnea: investigations with AVE0118 in anesthetized pigs. SLEEP 2013;36(5):699-708. PMID:23633752
The collapse of pelagic fishes in the upper San Francisco estuary
Sommer, T.; Armor, C.; Baxter, R.; Breuer, R.; Brown, L.; Chotkowski, M.; Culberson, S.; Feyrer, F.; Gingras, M.; Herbold, B.; Kimmerer, W.; Mueller-Solger, A.; Nobriga, M.; Souza, K.
2007-01-01
Although the pelagic fish community of the upper San Francisco Estuary historically has shown substantial variability, a recent collapse has captured the attention of resource managers, scientists, legislators, and the general public. The ecological and management consequences of the decline are most serious for delta smelt (Hypomesus transpacificus), a threatened species whose narrow range overlaps with large water diversions that supply water to over 25 million people. The decline occurred despite recent moderate hydrology, which typically results in at least modest recruitment, and investments of hundreds of millions of dollars in habitat restoration and environmental water allocations to support native fishes. In response to the pelagic fish collapse, an ambitious multi-agency research team has been working since 2005 to evaluate the causes of the decline, which likely include a combination of factors: stock-recruitment effects, a decline in habitat quality, increased mortality rates, and reduced food availability due to invasive species.
Limits on low-energy neutrino fluxes with the Mont Blanc liquid scintillator detector
NASA Astrophysics Data System (ADS)
Aglietta, M.; Antonioli, P.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Khalchukov, F. F.; Korolkova, E. V.; Kortchaguin, P. V.; Kortchaguin, V. B.; Kudryavtsev, V. A.; Malguin, A. S.; Periale, L.; Ryassny, V. G.; Ryazhskaya, O. G.; Saavedra, O.; Trinchero, G.; Vernetto, S.; Yakushev, V. F.; Zatsepin, G. T.
1992-11-01
The LSD liquid scintillation detector has been operating since 1985 as an underground neutrino observatory in the Mont Blanc Laboratory with the main objective of detecting antineutrino bursts from collapsing stars. In August 1988 the construction of an additional lead and borex paraffin shield considerably reduced the radioactive background and increased the sensitivity of the apparatus. In this way the search for steady fluxes of low-energy neutrinos of different flavours through their interactions with free protons and carbon nuclei of the scintillator was made possible. No evidence for a galactic collapse was observed during the whole period of measurement. The corresponding 90% c.l. upper limit on the galactic collapses rate is 0.45 y -1 for a burst duration of ΔT ⩽ 10 s. After analysing the last 3 years data, the following 90% c.l. upper limits on the steady neutrino and antineutrino fluxes were obtained:
Volumetric Effects of Motor Cortex Injury on Recovery of Ipsilesional Dexterous Movements
Darling, Warren G.; Pizzimenti, Marc A.; Hynes, Stephanie M.; Rotella, Diane L.; Headley, Grant; Ge, Jizhi; Stilwell-Morecraft, Kimberly S.; McNeal, David W.; Solon-Cline, Kathryn M.; Morecraft, Robert J.
2011-01-01
Damage to the motor cortex of one hemisphere has classically been associated with contralateral upper limb paresis, but recent patient studies have identified deficits in both upper limbs. In non-human primates, we tested the hypothesis that the severity of ipsilesional upper limb motor impairment in the early post-injury phase depends on the volume of gray and white matter damage of the motor areas of the frontal lobe. We also postulated that substantial recovery would accompany minimal task practice and that ipsilesional limb recovery would be correlated with recovery of the contralesional limb. Gross (reaching) and fine hand motor functions were assessed for 3-12 months post-injury using two motor tests. Volumes of white and gray matter lesions were assessed using quantitative histology. Early changes in post-lesion motor performance were inversely correlated with white matter lesion volume indicating that larger lesions produced greater decreases in ipsilesional hand movement control. All monkeys showed improvements in ipsilesional hand motor skill during the post-lesion period, with reaching skill improvements being positively correlated with total lesion volume indicating larger lesions were associate with greater ipsilesional motor skill recovery. We suggest that reduced trans-callosal inhibition from the lesioned hemisphere may play a role in the observed skill improvements. Our findings show that significant ipsilesional hand motor recovery is likely to accompany injury limited to frontal motor areas. In humans, more pronounced ipsilesional motor deficits that invariably develop after stroke may, in part, be a consequence of more extensive subcortical white and gray matter damage. PMID:21703261
From a collage of microplates to stable continental crust - an example from Precambrian Europe
NASA Astrophysics Data System (ADS)
Korja, Annakaisa
2013-04-01
Svecofennian orogen (2.0-1.7 Ga) comprises the oldest undispersed orogenic belt on Baltica and Eurasian plate. Svecofennian orogenic belt evolved from a series of short-lived terrane accretions around Baltica's Archean nucleus during the formation of the Precambrian Nuna supercontinent. Geological and geophysical datasets indicate W-SW growth of Baltica with NE-ward dipping subduction zones. The data suggest a long-lived retreating subduction system in the southwestern parts whereas in the northern and central parts the northeasterly transport of continental fragments or microplates towards the continental nucleus is also documented. The geotectonic environment resembles that of the early stages of the Alpine-Himalayan or Indonesian orogenic system, in which dispersed continental fragments, arcs and microplates have been attached to the Eurasian plate margin. Thus the Svecofennian orogeny can be viewed as proxy for the initial stages of an internal orogenic system. Svecofennian orogeny is a Paleoproterozoic analogue of an evolved orogenic system where terrane accretion is followed by lateral spreading or collapse induced by change in the plate architecture. The exposed parts are composed of granitoid intrusions as well as highly deformed supracrustal units. Supracrustal rocks have been metamorphosed in LP-HT conditions in either paleo-lower-upper crust or paleo-upper-middle crust. Large scale seismic reflection profiles (BABEL and FIRE) across Baltica image the crust as a collage of terranes suggesting that the bedrock has been formed and thickened in sequential accretions. The profiles also image three fold layering of the thickened crust (>55 km) to transect old terrane boundaries, suggesting that the over-thickened bedrock structures have been rearranged in post-collisional spreading and/or collapse processes. The middle crust displays typical large scale flow structures: herringbone and anticlinal ramps, rooted onto large scale listric surfaces also suggestive of spreading. Close to the original ocean-continent plate boundary, in the core of the Svecofennian orogen, the thickened accretionary crust carries pervasive stretching lineations at surface and seismic vp-velocity anisotropy in the crust. The direction of spreading and crustal flow seems to be diverted by shapes of the pre-existing boundaries. It is concluded that lateral spreading and midcrustal flow not only rearrange the bedrock architecture but also stabilize the young accreted continental crust in emerging internal orogenic systems. Pre-existing microplate/terrane boundaries will affect the final architecture of the orogenic belt.
Constructing a patient-specific computer model of the upper airway in sleep apnea patients.
Dhaliwal, Sandeep S; Hesabgar, Seyyed M; Haddad, Seyyed M H; Ladak, Hanif; Samani, Abbas; Rotenberg, Brian W
2018-01-01
The use of computer simulation to develop a high-fidelity model has been proposed as a novel and cost-effective alternative to help guide therapeutic intervention in sleep apnea surgery. We describe a computer model based on patient-specific anatomy of obstructive sleep apnea (OSA) subjects wherein the percentage and sites of upper airway collapse are compared to findings on drug-induced sleep endoscopy (DISE). Basic science computer model generation. Three-dimensional finite element techniques were undertaken for model development in a pilot study of four OSA patients. Magnetic resonance imaging was used to capture patient anatomy and software employed to outline critical anatomical structures. A finite-element mesh was applied to the volume enclosed by each structure. Linear and hyperelastic soft-tissue properties for various subsites (tonsils, uvula, soft palate, and tongue base) were derived using an inverse finite-element technique from surgical specimens. Each model underwent computer simulation to determine the degree of displacement on various structures within the upper airway, and these findings were compared to DISE exams performed on the four study patients. Computer simulation predictions for percentage of airway collapse and site of maximal collapse show agreement with observed results seen on endoscopic visualization. Modeling the upper airway in OSA patients is feasible and holds promise in aiding patient-specific surgical treatment. NA. Laryngoscope, 128:277-282, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.
Eckert, Danny J; Malhotra, Atul; Wellman, Andrew; White, David P
2014-04-01
The effect of common sedatives on upper airway physiology and breathing during sleep in obstructive sleep apnea (OSA) has been minimally studied. Conceptually, certain sedatives may worsen OSA in some patients. However, sleep and breathing could improve with certain sedatives in patients with OSA with a low respiratory arousal threshold. This study aimed to test the hypothesis that trazodone increases the respiratory arousal threshold in patients with OSA and a low arousal threshold. Secondary aims were to examine the effects of trazodone on upper airway dilator muscle activity, upper airway collapsibility, and breathing during sleep. Patients were studied on 4 separate nights according to a within-subjects cross-over design. Sleep physiology laboratory. Seven patients with OSA and a low respiratory arousal threshold. In-laboratory polysomnograms were obtained at baseline and after 100 mg of trazodone was administered, followed by detailed overnight physiology experiments under the same conditions. During physiology studies, continuous positive airway pressure was transiently lowered to measure arousal threshold (negative epiglottic pressure prior to arousal), dilator muscle activity (genioglossus and tensor palatini), and upper airway collapsibility (Pcrit). Trazodone increased the respiratory arousal threshold by 32 ± 6% (-11.5 ± 1.4 versus -15.3 ± 2.2 cmH2O, P < 0.01) but did not alter the apnea-hypopnea index (39 ± 12 versus 39 ± 11 events/h sleep, P = 0.94). Dilator muscle activity and Pcrit also did not systematically change with trazodone. Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold without major impairment in dilator muscle activity or upper airway collapsibility. However, the magnitude of change in arousal threshold was insufficient to overcome the compromised upper airway anatomy in these patients.
On the Maximum Mass of Accreting Primordial Supermassive Stars
DOE Office of Scientific and Technical Information (OSTI.GOV)
Woods, T. E.; Heger, Alexander; Whalen, Daniel J.
Supermassive primordial stars are suspected to be the progenitors of the most massive quasars at z ∼ 6. Previous studies of such stars were either unable to resolve hydrodynamical timescales or considered stars in isolation, not in the extreme accretion flows in which they actually form. Therefore, they could not self-consistently predict their final masses at collapse, or those of the resulting supermassive black hole seeds, but rather invoked comparison to simple polytropic models. Here, we systematically examine the birth, evolution, and collapse of accreting, non-rotating supermassive stars under accretion rates of 0.01–10 M {sub ⊙} yr{sup −1} using themore » stellar evolution code Kepler . Our approach includes post-Newtonian corrections to the stellar structure and an adaptive nuclear network and can transition to following the hydrodynamic evolution of supermassive stars after they encounter the general relativistic instability. We find that this instability triggers the collapse of the star at masses of 150,000–330,000 M {sub ⊙} for accretion rates of 0.1–10 M {sub ⊙} yr{sup −1}, and that the final mass of the star scales roughly logarithmically with the rate. The structure of the star, and thus its stability against collapse, is sensitive to the treatment of convection and the heat content of the outer accreted envelope. Comparison with other codes suggests differences here may lead to small deviations in the evolutionary state of the star as a function of time, that worsen with accretion rate. Since the general relativistic instability leads to the immediate death of these stars, our models place an upper limit on the masses of the first quasars at birth.« less
Effects of high shock pressures and pore morphology on hot spot mechanisms in HMX
NASA Astrophysics Data System (ADS)
Springer, H. K.; Tarver, C. M.; Bastea, S.
2017-01-01
The shock initiation and detonation behavior of heterogeneous solid explosives is governed by its microstructure and reactive properties. New additive manufacturing techniques offer unprecedented control of explosive microstructures previously impossible, enabling us to develop novel explosives with tailored shock sensitivity and detonation properties. Since microstructure-performance relationships are not well established for explosives, there is little material design guidance for these manufacturing techniques. In this study, we explore the effects of high shock pressures (15-38 GPa) with long shock durations and different pore morphologies on hot spot mechanisms in HMX. HMX is chosen as the model material because we have experimental data on many of the chemical-thermal-mechanical properties required for pore collapse simulations. Our simulations are performed using the multi-physics arbitrary Lagrangian Eulerian finite element hydrocode, ALE3D, with Cheetah-based models for the unreacted and the product equation-of-states. We use a temperature-dependent specific heat with the unreacted equation-of-state and a temperature-dependent viscosity model to ensure accurate shock temperatures for subsequent chemistry. The Lindemann Law model is used for shock melting in HMX. In contrast to previous pore collapse studies at lower shock pressures (≤10 GPa) in HMX and shorter post-collapse burning times, our calculations show that shock melting occurs above 15 GPa due to higher bulk heating and a prominent elongated ("jet-like") hot spot region forms at later times. The combination of the elongated, post-collapse hot spot region and the higher bulk heating with increasing pressure dramatically increases the growth rate of reaction. Our calculations show that the reaction rate, dF/dt, increases with increasing shock pressure. We decompose the reaction rate into ignition ((dF/dt)ig) and growth ((dF/dt)gr) phases to better analyze our results. We define the ignition phase to primarily include pore collapse and growth phase to primarily include post-collapse grain burning. We are able to track late-time, post-collapse burning due to the unique loading conditions employed in these calculations. We find that (dF/dt)gr > (dF/dt)ig for all pressures considered. (dF/dt)gr changes more significantly from 25 to 38 GPa (from 0.05/µs to >10-100/µs) than from 15 to 25 GPa (from 0.005/µs to 0.05/µs). There is a three order-of-magnitude difference in the reaction from 15 to 38 GPa just after pore collapse. This is qualitatively consistent with fitting the (macroscopic) Ignition and Growth model to high pressure shock initiation data, where much larger reaction fractions are needed to capture the early stages of reaction. Calculated burn rates demonstrate better agreement with data at intermediate times in the growth phase for 15 to 25 GPa and late times for 30 GPa then at any time in the growth phase for 38 GPa. Our calculations are much higher than burn rate data at the earliest times in the growth phase for all pressures, which may reflect the higher localized pressures and temperatures just after pore collapse in the ignition phase. Our calculations with spherical, conical, and elliptical pores show that the influence of morphology on reaction rate is pressure dependent and the most influential pore shapes at lower pressures aren't the same at higher pressures in the regime studied. Altogether these studies provide the basis for developing microstructure-aware models that can be used to design new explosives with optimal performance-safety characteristics. Such models can be used to guide additive manufacturing of explosives and fully exploit their disruptive nature.
Katsumi, Keiichi; Hirano, Toru; Watanabe, Kei; Ohashi, Masayuki; Yamazaki, Akiyoshi; Ito, Takui; Sawakami, Kimihiko; Sano, Atsuki; Kikuchi, Ren; Endo, Naoto
2016-11-01
The study aimed to investigate the clinical outcomes and limitations after vertebroplasty with posterior spinal fusion (VP+PSF) without neural decompression for osteoporotic vertebral collapse. We conducted a prospective multicenter study including 45 patients (12 men and 33 women, mean age: 77.0 years) evaluated between 2008 and 2012. Operation time, blood loss, visual analog scale (VAS) of back pain, neurological status, kyphosis angle in the fused area, and vertebral union of the collapsed vertebra were evaluated. The mean operation time was 162 min and blood loss was 381 mL. The postoperative VAS score significantly improved, and the neurological status improved in 35 patients (83 %), and none of the remaining patients demonstrated a deteriorating neurological status at two years post-operatively. The mean kyphosis angle pre-operatively, immediately post-operatively, and two years post-operatively was 23.8°, 10.7°, and 24.3°, respectively, and there was no significant difference between the angles pre-operatively and two years post-operatively. The extensive correction of kyphosis >16° was a risk factor for a higher correction loss and subsequent fracture. Union of the collapsed vertebra was observed in 43 patients (95 %) at two years post-operatively. The present study suggests that spinal stabilization rather than neural decompression is essential to treat OVC. Short-segment VP+PSF can achieve a high union rate of collapsed vertebra and provide a significant improvement in back pain or neurological status with less invasive surgery, but has a limit of kyphosis correction more than 16°.
NASA Astrophysics Data System (ADS)
Kumano, Teruhisa
As known well, two of the fundamental processes which give rise to voltage collapse in power systems are the on load tap changers of transformers and dynamic characteristics of loads such as induction machines. It has been well established that, comparing among these two, the former makes slower collapse while the latter makes faster. However, in realistic situations, the load level of each induction machine is not uniform and it is well expected that only a part of loads collapses first, followed by collapse process of each load which did not go into instability during the preceding collapses. In such situations the over all equivalent collapse behavior viewed from bulk transmission level becomes somewhat different from the simple collapse driven by one aggregated induction machine. This paper studies the process of cascaded voltage collapse among many induction machines by time simulation, where load distribution on a feeder line is modeled by several hundreds of induction machines and static impedance loads. It is shown that in some cases voltage collapse really cascades among induction machines, where the macroscopic load dynamics viewed from upper voltage level makes slower collapse than expected by the aggregated load model. Also shown is the effects of machine protection of induction machines, which also makes slower collapse.
Marques, Melania; Genta, Pedro R; Sands, Scott A; Azarbazin, Ali; de Melo, Camila; Taranto-Montemurro, Luigi; White, David P; Wellman, Andrew
2017-03-01
In some patients, obstructive sleep apnea (OSA) can be resolved with improvement in pharyngeal patency by sleeping lateral rather than supine, possibly as gravitational effects on the tongue are relieved. Here we tested the hypothesis that the improvement in pharyngeal patency depends on the anatomical structure causing collapse, with patients with tongue-related obstruction and epiglottic collapse exhibiting preferential improvements. Twenty-four OSA patients underwent upper airway endoscopy during natural sleep to determine the pharyngeal structure associated with obstruction, with simultaneous recordings of airflow and pharyngeal pressure. Patients were grouped into three categories based on supine endoscopy: Tongue-related obstruction (posteriorly located tongue, N = 10), non-tongue related obstruction (collapse due to the palate or lateral walls, N = 8), and epiglottic collapse (N = 6). Improvement in pharyngeal obstruction was quantified using the change in peak inspiratory airflow and minute ventilation lateral versus supine. Contrary to our hypothesis, patients with tongue-related obstruction showed no improvement in airflow, and the tongue remained posteriorly located while lateral. Patients without tongue involvement showed modest improvement in airflow (peak flow increased 0.07 L/s and ventilation increased 1.5 L/min). Epiglottic collapse was virtually abolished with lateral positioning and ventilation increased by 45% compared to supine position. Improvement in pharyngeal patency with sleeping position is structure specific, with profound improvements seen in patients with epiglottic collapse, modest effects in those without tongue involvement and-unexpectedly-no effect in those with tongue-related obstruction. Our data refute the notion that the tongue falls back into the airway during sleep via gravitational influences. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.
Genta, Pedro R.; Sands, Scott A.; Azarbazin, Ali; de Melo, Camila; Taranto-Montemurro, Luigi; White, David P.; Wellman, Andrew
2017-01-01
Abstract Objectives: In some patients, obstructive sleep apnea (OSA) can be resolved with improvement in pharyngeal patency by sleeping lateral rather than supine, possibly as gravitational effects on the tongue are relieved. Here we tested the hypothesis that the improvement in pharyngeal patency depends on the anatomical structure causing collapse, with patients with tongue-related obstruction and epiglottic collapse exhibiting preferential improvements. Methods: Twenty-four OSA patients underwent upper airway endoscopy during natural sleep to determine the pharyngeal structure associated with obstruction, with simultaneous recordings of airflow and pharyngeal pressure. Patients were grouped into three categories based on supine endoscopy: Tongue-related obstruction (posteriorly located tongue, N = 10), non-tongue related obstruction (collapse due to the palate or lateral walls, N = 8), and epiglottic collapse (N = 6). Improvement in pharyngeal obstruction was quantified using the change in peak inspiratory airflow and minute ventilation lateral versus supine. Results: Contrary to our hypothesis, patients with tongue-related obstruction showed no improvement in airflow, and the tongue remained posteriorly located while lateral. Patients without tongue involvement showed modest improvement in airflow (peak flow increased 0.07 L/s and ventilation increased 1.5 L/min). Epiglottic collapse was virtually abolished with lateral positioning and ventilation increased by 45% compared to supine position. Conclusions: Improvement in pharyngeal patency with sleeping position is structure specific, with profound improvements seen in patients with epiglottic collapse, modest effects in those without tongue involvement and—unexpectedly—no effect in those with tongue-related obstruction. Our data refute the notion that the tongue falls back into the airway during sleep via gravitational influences. PMID:28329099
Chang, Yi-Chung; Huon, Leh-Kiong; Pham, Van-Truong; Chen, Yunn-Jy; Jiang, Sun-Fen; Shih, Tiffany Ting-Fang; Tran, Thi-Thao; Wang, Yung-Hung; Lin, Chen; Tsao, Jenho; Lo, Men-Tzung; Wang, Pa-Chun
2014-12-01
Progressive narrowing of the upper airway increases airflow resistance and can produce snoring sounds and apnea/hypopnea events associated with sleep-disordered breathing due to airway collapse. Recent studies have shown that acoustic properties during snoring can be altered with anatomic changes at the site of obstruction. To evaluate the instantaneous association between acoustic features of snoring and the anatomic sites of obstruction, a novel method was developed and applied in nine patients to extract the snoring sounds during sleep while performing dynamic magnetic resonance imaging (MRI). The degree of airway narrowing during the snoring events was then quantified by the collapse index (ratio of airway diameter preceding and during the events) and correlated with the synchronized acoustic features. A total of 201 snoring events (102 pure retropalatal and 99 combined retropalatal and retroglossal events) were recorded, and the collapse index as well as the soft tissue vibration time were significantly different between pure retropalatal (collapse index, 2 ± 11%; vibration time, 0.2 ± 0.3 s) and combined (retropalatal and retroglossal) snores (collapse index, 13 ± 7% [P ≤ 0.0001]; vibration time, 1.2 ± 0.7 s [P ≤ 0.0001]). The synchronized dynamic MRI and acoustic recordings successfully characterized the sites of obstruction and established the dynamic relationship between the anatomic site of obstruction and snoring acoustics.
NASA Astrophysics Data System (ADS)
Goodenough, K. M.; Thomas, R. J.; De Waele, B.; Key, R. M.; Schofield, D. I.; Bauer, W.; Tucker, R. D.; Rafahatelo, J.-M.; Rabarimanana, M.; Ralison, A. V.; Randriamananjara, T.
2010-04-01
Late tectonic, post-collisional granite suites are a feature of many parts of the Late Neoproterozoic to Cambrian East African Orogen (EAO), where they are generally attributed to late extensional collapse of the orogen, accompanied by high heat flow and asthenospheric uprise. The Maevarano Suite comprises voluminous plutons which were emplaced in some of the tectonostratigraphic terranes of northern Madagascar, in the central part of the EAO, following collision and assembly during a major orogeny at ca. 550 Ma. The suite comprises three main magmatic phases: a minor early phase of foliated gabbros, quartz diorites, and granodiorites; a main phase of large batholiths of porphyritic granitoids and charnockites; and a late phase of small-scale plutons and sheets of monzonite, syenite, leucogranite and microgranite. The main phase intrusions tend to be massive, but with variably foliated margins. New U-Pb SHRIMP zircon data show that the whole suite was emplaced between ca. 537 and 522 Ma. Geochemically, all the rocks of the suite are enriched in the LILE, especially K, and the LREE, but are relatively depleted in Nb, Ta and the HREE. These characteristics are typical of post-collisional granitoids in the EAO and many other orogenic belts. It is proposed that the Maevarano Suite magmas were derived by melting of sub-continental lithospheric mantle that had been enriched in the LILE during earlier subduction events. The melting occurred during lithospheric delamination, which was associated with extensional collapse of the East African Orogen.
Fehlings, Michael G; Kim, Kee D; Aarabi, Bizhan; Rizzo, Marco; Bond, Lisa M; McKerracher, Lisa; Vaccaro, Alexander R; Okonkwo, David O
2018-05-01
Traumatic spinal cord injury (SCI) is associated with a lifetime of disability stemming from loss of motor, sensory, and autonomic functions; these losses, along with increased comorbid sequelae, negatively impact health outcomes and quality of life. Early decompression surgery post-SCI can enhance patient outcomes, but does not directly facilitate neural repair and regeneration. Currently, there are no U.S. Food and Drug Administration-approved pharmacological therapies to augment motor function and functional recovery in individuals with traumatic SCI. After an SCI, the enzyme, Rho, is activated by growth-inhibitory factors and regulates events that culminate in collapse of the neuronal growth cone, failure of axonal regeneration, and, ultimately, failure of motor and functional recovery. Inhibition of Rho activation is a potential treatment for injuries such as traumatic SCI. VX-210, an investigational agent, inhibits Rho. When administered extradurally after decompression (corpectomy or laminectomy) and stabilization surgery in a phase 1/2a study, VX-210 was well tolerated. Here, we describe the design of the SPRING trial, a multicenter, phase 2b/3, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of VX-210 (NCT02669849). A subset of patients with acute traumatic cervical SCI is currently being enrolled in the United States and Canada. Medical, neurological, and functional changes are evaluated at 6 weeks and at 3, 6, and 12 months after VX-210 administration. Efficacy will be assessed by the primary outcome measure, change in upper extremity motor score at 6 months post-treatment, and by secondary outcomes that include question-based and task-based evaluations of functional recovery.
NASA Astrophysics Data System (ADS)
Petit, Olivier; Kuper, Marcel; López-Gunn, Elena; Rinaudo, Jean-Daniel; Daoudi, Ali; Lejars, Caroline
2017-09-01
The aim of this paper is to investigate the notion of collapse of agricultural groundwater economies using the adaptive-cycle analytical framework. This framework was applied to four case studies in southern Europe and North Africa to question and discuss the dynamics of agricultural groundwater economies. In two case studies (Saiss in Morocco and Clain basin in France), the imminent physical or socio-economic collapse was a major concern for stakeholders and the early signs of collapse led to re-organization of the groundwater economy. In the other two cases (Biskra in Algeria and Almeria in Spain), collapse was either not yet a concern or had been temporarily resolved through increased efficiency and access to additional water resources. This comparative analysis shows the importance of taking the early signs of collapse into account. These signs can be either related to resource depletion or to environmental and socio-economic impacts. Beyond these four case studies, the large number of groundwater economies under threat in (semi-)arid areas should present a warning regarding their possible collapse. Collapse can have severe and irreversible consequences in some cases, but it can also mean new opportunities and changes.
Bang, Dae-Hyouk; Shin, Won-Seob; Choi, Ho-Suk
2018-01-01
Reducing compensatory strategies during repetitive upper-limb training may be helpful in relearning motor skills. To explore the effects of modified constraint-induced movement therapy (mCIMT), additionally modified by adding trunk restraint (TR), on upper-limb function and activities of daily living (ADLs) in early post-stroke patients. Twenty-four participants with early stroke were randomly assigned to mCIMT combined with TR (mCIMT + TR) or mCIMT alone. Each group underwent twenty sessions (1 h/d, 5 d/wk for 4 weeks). Patients were assessed with the action research arm test (ARAT), the Fugl-Meyer Assessment-Upper extremity (FMA-UE), the Modified Barthel index (MBI), the Maximal elbow extension angle during reaching (MEEAR), and Motor Activity Logs (MAL-AOU and MAL-QOM). The mCIMT + TR group exhibited greater improvement in the ARAT, FMA-UE, MBI, MEEAR, and MAL-AOU, and MAL-QOM than the mCIMT group. Statistical analyses showed significant differences in ARAT (P = 0.003), FMA-UE (P = 0.042), MBI (P = 0.001), MEEAR (P = 0.002), and MAL-AOU (P = 0.005) between the groups. Modified CIMT combined with TR may be more effective than mCIMT alone in improving upper-limb function and ADLs in patients with early stroke.
SUPERNOVAE POWERED BY MAGNETARS THAT TRANSFORM INTO BLACK HOLES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moriya, Takashi J.; Metzger, Brian D.; Blinnikov, Sergei I., E-mail: takashi.moriya@nao.ac.jp
2016-12-10
Rapidly rotating, strongly magnetized neutron stars (NSs; magnetars) can release their enormous rotational energy via magnetic spin-down, providing a power source for bright transients such as superluminous supernovae (SNe). On the other hand, particularly massive (so-called supramassive) NSs require a minimum rotation rate to support their mass against gravitational collapse, below which the NS collapses to a black hole (BH). We model the light curves (LCs) of SNe powered with magnetars that transform into BHs. Although the peak luminosities can reach high values in the range of superluminous SNe, their post maximum LCs can decline very rapidly because of the suddenmore » loss of the central energy input. Early BH transformation also enhances the shock breakout signal from the magnetar-driven bubble relative to the main SN peak. Our synthetic LCs of SNe powered by magnetars transforming to BHs are consistent with those of some rapidly evolving bright transients recently reported by Arcavi et al.« less
Did mud contribute to freeway collapse?
NASA Astrophysics Data System (ADS)
Hough, Susan E.; Friberg, Paul A.; Busby, Robert; Field, Edward F.; Jacob, Klaus H.; Borcherdt, Roger D.
At least 41 people were killed October 17 when the upper tier of the Nimitz Freeway in Oakland, Calif., collapsed during the Ms = 7.1 Loma Prieta earthquake. Seismologists studying aftershocks concluded that soil conditions and resulting ground motion amplification were important in the failure of the structure and should be considered in the reconstruction of the highway.Structural design weaknesses in the two-tiered freeway, known as the Cypress structure, had been identified before the tragedy. The seismologists, from Lamont Doherty Geological Observatory in Palisades, N.Y., and the U.S. Geological Survey in Menlo Park, Calif., found that the collapsed section was built on fill over Bay mud. A southern section of the Cypress structure built on alluvium of Quaternary age did not collapse (see Figure 1).
NASA Astrophysics Data System (ADS)
Walter, W. R.; Dodge, D. A.; Ichinose, G.; Myers, S. C.; Ford, S. R.; Pitarka, A.; Pyle, M. L.; Pasyanos, M.; Matzel, E.; Rodgers, A. J.; Mellors, R. J.; Hauk, T. F.; Kroll, K.
2017-12-01
On September 3, 2017, an mb 6.3 seismic event was reported by the USGS in the vicinity of the DPRK nuclear test site at Punggye-ri. Shortly afterwards DPRK declared it had conducted a nuclear explosion. The seismic signals indicate this event is roughly an order of magnitude larger than the largest of the previous five DPRK declared nuclear tests. In addition to its size, this explosion was different from previous DPRK tests in being associated with a number of additional seismic events. Approximately eight and a half minutes after the explosion a seismic event reported as ML 4.0 by the USGS occurred. Regional waveform modeling indicated this event had a collapse mechanism (e.g. Ichinose et al., 2017, written communication). On September 23 and again on October 12, 2017, seismic events were reported near the DPRK test site by the USGS and the CTBTO (on 9/23/17 two events: USGS ML 3.6 and USGS ML 2.6; and on 10/12/17 one event: USGS mb(Lg) 2.9). Aftershocks following underground nuclear testing are expected, though at much lower magnitudes and rates than for comparably sized earthquakes. This difference in aftershock production has been proposed by Ford and Walter (2010), and others as a potential source-type discriminant. Seismic signals from the collapse of cavities formed by underground nuclear testing have also been previously observed. For example, the mb 5.7 nuclear test ATRISCO in Nevada in 1982 was followed twenty minutes later by a collapse with an mb of 4.0. Here we examine the seismic characteristics of nuclear tests, post-test collapses and post-test aftershocks from both the former Nevada test site and the DPRK test site to better understand the differences between these different source-type signals. In particular we look at discriminants such as P/S ratios, to see if there are unique characteristics to post-test collapses and aftershocks. Finally, we apply correlation methods to continuous data at regional stations to look for additional seismic signals that might have an apparent association with the DPRK nuclear testing, post-testing collapses and post-test induced seismicity.
NASA Astrophysics Data System (ADS)
Goodbody-Gringley, Gretchen; Wong, Kevin H.; Becker, Danielle M.; Glennon, Keegan; de Putron, Samantha J.
2018-06-01
Early life history traits of brooding corals are often affected by the environmental conditions experienced by parental colonies. Such parental effects can impact offspring survival, which influences the overall success of a population as well as resilience to environmental challenges. This study examines the reproductive ecology and early life history traits of the brooding coral Porites astreoides across a depth gradient in Bermuda. Fecundity, larval size, larval Symbiodinium density, and settlement success, as well as post-metamorphic juvenile survival, growth, and Symbiodinium density were compared across three reef sites representing an inshore patch reef (2-5 m), an offshore rim reef (8-10 m), and an upper-mesophotic reef (30-33 m). Although fecundity did not differ across sites, larvae produced by colonies on the patch reef site were smaller, had lower Symbiodinium densities, and had lower rates of settlement and juvenile survival compared to larvae from colonies on the rim and upper-mesophotic reef sites. Larvae produced by colonies from the rim and upper-mesophotic sites did not differ in size or Symbiodinium densities; however, rates of settlement, growth, and survival were higher for larvae from the upper-mesophotic site compared to those from the rim reef site. These results indicate that offspring quality and success vary among sites with differing environmental conditions and may imply higher recruitment potential and resilience for upper-mesophotic corals.
NASA Astrophysics Data System (ADS)
Albert, H.; Costa Rodriguez, F.; Herrin, J. S.; Di Muro, A.; Metrich, N.
2017-12-01
Summit caldera collapse is a rare event at Piton de la Fournaise. One such event occurred in 2007 during one of the largest historic eruptions of more than 200 Mm3 of magma. Effusion of aphyric basalts initiated at the summit area in mid-February, followed by the migration of active vents in March and early April to progressively lower elevations. Collapse of a 1 km diameter summit caldera occurred on April 5th while effusion of crystal rich lava continued until May 1st. Here we investigate these events through timescales recorded in olivine crystals and their melt inclusions (MIs) using a diffusion modelling approach. Olivine crystals from the early tephra emitted just before caldera collapse and from the post caldera collapse lava display similar compositions and zoning patterns. Fo [%Fo=100*Mg/(Mg+Fe)] values range from ≈82 to ≈86 and the phenocrysts are complexly zoned including a reverse followed by normal zoning. Fo≈84 cores are surrounded by a Fo≈86 plateau. In contact with the surrounding matrix or MIs, crystals exhibit normal zoning toward values of Fo≈82-83. Phosphorus distribution revealed in 2D X-Ray maps shows complex patterns that can be interpreted as early skeletal growth likely responsible for entrapment of MIs. Diffusion modeling of Fo, Ca, and Ni reveals two distinct magma residence timescales recorded in olivine. The inner reversed-zoned profiles yield timescales of 1-2 years, while normally-zoned profiles at crystal rims and also adjacent to MIs yield timescales of only a few days. Modelling of the P zoning patterns is consistent with the 1-2 year timescales obtained from reversely-zoned profiles. H2O contents of olivine-hosted MIs range from 0.35-1.16 wt%. Selective loss of water in some MIs suggests diffusive re-equilibration between the MIs and host magma during ascent. We have applied H2O diffusion modeling to estimate timescales of water loss of a few days, consistent with the results of Fo/Ca/Ni modeling of olivine profiles. We infer that the timescales of one to two years obtained from reversely-zoned profiles and P in olivine could record residence in a long-lived intrusive body sitting below the volcano summit which was fluidized during the eruption leading to caldera collapse. Timescales of one to a few days obtained from normal zoning and water loss record magma ascent during the 2007 eruption.
Bachmann, Olivier; Dungan, M.A.; Lipman, P.W.
2002-01-01
More than 5000 km3 of nearly compositionally homogeneous crystalrich dacite (~68 wt % SiO2: ~45% Pl + Kfs + Qtz + Hbl + Bt + Spn + Mag + Ilm + Ap + Zrn + Po) erupted from the Fish Canyon magma body during three phases: (1) the pre-caldera Pagosa Peak Dacite (an unusual poorly fragmented pyroclastic deposit, ~ 200 km3); (2) the syn-collapse Fish Canyon Tuff (one of the largest known ignimbrites, ~ 5000 km3); (3) the post-collapse Nutras Creek Dacite (a volumetrically minor lava). The late evolution of the Fish Canyon magma is characterized by rejuvenation of a near-solidus upper-crustal intrusive body (mainly crystal mush) of batholithic dimensions. The necessary thermal input was supplied by a shallow intrusion of more mafic magma represented at the surface by sparse andesitic enclaves in late-erupted Fish Canyon Tuff and by the post-caldera Huerto Andesite. The solidified margins of this intrusion are represented by holocrystalline xenoliths with Fish Canyon mineralogy and mineral chemistry and widely dispersed partially remelted polymineralic aggregates, but dehydration melting was not an important mechanism in the rejuvenation of the Fish Canyon magma. Underlying mafic magma may have evolved H2O-F-S-Cl-rich fluids that fluxed melting in the overlying crystal mush. Manifestations of the late up-temperature magma evolution are: (1) resorbed quartz, as well as feldspars displaying a wide spectrum of textures indicative of both resorption and growth, including Rapakivi textures and reverse growth zoning (An27-28 to An32-33) at the margins of many plagioclase phenocrysts; (2) high Sr, Ba, and Eu contents in the high-SiO2 rhyolite matrix glass, which are inconsistent with extreme fractional crystallization of feldspar; (3) oscillatory and reverse growth zoning toward the margins of many euhedral hornblende phenocrysts (rimward increases from ~5??5-6 to 7??7-8??5 wt % Al2O3). Homogeneity in magma composition at the chamber-wide scale, contrasting with extreme textural and chemical complexities at the centimeter-millimeter scale, is consistent with a dynamic environment, wherein crystals with a variety of growth and resorption histories were juxtaposed shortly before eruption by convective currents.
NASA Astrophysics Data System (ADS)
Calvari, Sonia; Intrieri, Emanuele; Di Traglia, Federico; Bonaccorso, Alessandro; Casagli, Nicola; Cristaldi, Antonio
2016-05-01
Crater-wall collapses are fairly frequent at active volcanoes and they are normally studied through the analysis of their deposits. In this paper, we present an analysis of the 12 January 2013 crater-wall collapse occurring at Stromboli volcano, investigated by means of a monitoring network comprising visible and infrared webcams and a Ground-Based Interferometric Synthetic Aperture Radar. The network revealed the triggering mechanisms of the collapse, which are comparable to the events that heralded the previous effusive eruptions in 1985, 2002, 2007 and 2014. The collapse occurred during a period of inflation of the summit cone and was preceded by increasing explosive activity and the enlargement of the crater. Weakness of the crater wall, increasing magmastatic pressure within the upper conduit induced by ascending magma and mechanical erosion caused by vent opening at the base of the crater wall and by lava fingering, are considered responsible for triggering the collapse on 12 January 2013 at Stromboli. We suggest that the combination of these factors might be a general mechanism to generate crater-wall collapse at active volcanoes.
Volcano collapse promoted by hydrothermal alteration and edifice shape, Mount Rainier, Washington
Reid, M.E.; Sisson, T.W.; Brien, D.L.
2001-01-01
Catastrophic collapses of steep volcano flanks threaten many populated regions, and understanding factors that promote collapse could save lives and property. Large collapses of hydrothermally altered parts of Mount Rainier have generated far-traveled debris flows; future flows would threaten densely populated parts of the Puget Sound region. We evaluate edifice collapse hazards at Mount Rainier using a new three-dimensional slope stability method incorporating detailed geologic mapping and subsurface geophysical imaging to determine distributions of strong (fresh) and weak (altered) rock. Quantitative three-dimensional slope stability calculations reveal that sizeable flank collapse (>0.1 km3) is promoted by voluminous, weak, hydrothermally altered rock situated high on steep slopes. These conditions exist only on Mount Rainier's upper west slope, consistent with the Holocene debris-flow history. Widespread alteration on lower flanks or concealed in regions of gentle slope high on the edifice does not greatly facilitate collapse. Our quantitative stability assessment method can also provide useful hazard predictions using reconnaissance geologic information and is a potentially rapid and inexpensive new tool for aiding volcano hazard assessments.
Seismicity associated with dome growth and collapse at the Soufriere Hills Volcano, Montserrat
Miller, A.D.; Stewart, R.C.; White, R.A.; Luckett, R.; Baptie, B.J.; Aspinall, W.P.; Latchman, J.L.; Lynch, L.L.; Voight, B.
1998-01-01
Varied seismicity has accompanied growth and collapse of the lava dome of the Soufriere Hills Volcano, Montserrat. Earthquakes have been classified as either volcano-tectonic, long-period or hybrid, and daily variations in the numbers of events have mapped changes in the style of eruption. Repetitive hybrid earthquakes were common during the first months of dome growth. In July 1996 the style of seismicity changed and regular short-lived hybrid earthquake swarms became common. This change was probably caused by an increase in the magma flux. Earthquake swarms have preceded almost all major dome collapses, and have accompanied cyclical deformation, thought to be due to a built-up of pressure in the upper conduit which is later released by magma moving into the dome.Varied seismicity has accompanied growth and collapse of the lava dome of the Soufriere Hills Volcano, Montserrat. Earthquakes have been classified as either volcano-tectonic, long-period or hybrid, and daily variations in the numbers of events have mapped changes in the style of eruption. Repetitive hybrid earthquakes were common during the first months of dome growth. In July 1996 the style of seismicity changed and regular, short-lived hybrid earthquake swarms became common. This change was probably caused by an increase in the magma flux. Earthquake swarms have preceded almost all major dome collapses, and have accompanied cyclical deformation, thought to be due to a build-up of pressure in the upper conduit which is later released by magma moving into the dome.
NASA Astrophysics Data System (ADS)
Matenco, Liviu; Toljic, Marinko; Ducea, Mihai; Stojadinovic, Uros
2010-05-01
Formation of large extensional detachments during orogenic collapse can follow inherited weakness zones such as major asymmetries given by pre-existing subduction zones active during mountain building processes. This is valid in particular in low-topography foreland coupling orogens of Mediterranean type where large amounts of deformation is concentrated in their lower plates, favoring weakness zones activated during a subsequent phase of extensional collapse. One good place to study the orogenic collapse post-dating major collision is the NE margin of the Dinarides in central and western Serbia, where Cretaceous-Eocene shortening and collision was recorded in the Alpine Tethys Sava zone between the European-derived Dacia and Tisza mega-units and the lower Adriatic plate. This is the same place where the Pannonian basin formed as a Miocene back-arc basin in response to a different subduction and roll-back taking place along the external Carpathians. A lineament of Paleogene and Miocene plutons is observed at the northern and eastern margin of the Dinarides, interpreted to be the product of both syn- to post-orogenic subduction magmatism and of decompressional melting during the Pannonian extension. Two of these plutons, Cer and Bukulja, located in western and respectively central Serbia, are intruded in the Jadar-Kopaonik composite thrust sheet, part of the lower Adriatic plate, near the contact with the main suture formed during the Cretaceous-Eocene subduction of the Sava zone. The Lower Miocene age (19-17Ma) Bukulja intrusion is a S-type granite with rare aplitic veins (Cvetkovic et al., 2007). The Cer intrusive complex is a S type two mica granite of around 16Ma in age with an older I-type quartz monzonite component (Koroneos et al. in press). Both granitoids are intruded into the Jadar-Kopaonik metamorphic series, which are in direct contact along the northern, eastern and southern flank with non-metamorphosed, mainly clastic sediments of Cretaceous-Miocene in age and, in the case of Bukulja, with serpentinized ophiolites. The metamorphic sequences are generally characterized by a Paleozoic age meta-sedimentary basement and a meta-sedimentary and meta-volcanic sequence. In the case of Bukulja, a succession of contrasting metamorphosed lithologies has been observed such as sandstones, black limestones, shallow water white limestones, basic volcanic sequences, deep nodular limestones and turbiditic sequences. The lower part of the sequence represents a metamorphosed Triassic sequence similar to what has been defined as the Kopaonik and Studenica series in southern Serbia. This part of the sequence is characterized by at least 3 successive stages of folding, asymmetric folds with WSW-ward vergence and NNE-SSW upright folds being affected by vertical flattening folds associated with extension (see also Marovic et al., 2007). The upper part of the sequence, which is the only part outcropping along the eastern flank of the Cer granitoid, is made up by metamorphosed distal turbidites which have been palinologically dated in Bukulja as Upper Cretaceous in age. This is the metamorphosed equivalent of the Upper Cretaceous - Eocene "flysch"-type of deposits commonly observed elsewhere in the main Sava subduction zone. These rocks are overprinted with a pervasive and strong extensional milonitic foliation indicating top-100 movement of the hanging-wall and are in direct contact with non-metamorphosed, but similar Upper Cretaceous distal turbidites. This suggests a large-scale tectonic omission along the eastern flanks of the Bukulja and Cer detachment. In the case of Bukulja, the extension was associated with the formation of the Early Miocene Morava basin in the detachment hanging-wall, which is an endemic lacustrine precursor of the much larger Middle-Late Miocene Pannonian basin. These finding points towards a bi-modal evolution of the internal Dinarides in central and western Serbia near the present-day contact with the Pannonian basin. An Upper Cretaceous-Eocene phase of top-WSW shortening and metamorphism in the Sava zone and its subducting lower Adriatic plate was subsequently followed by massive core-complex exhumation and top-E directed extension during initiation of the Carpathians back-arc extension. Interestingly, the newly defined extensional detachments accompanying the Pannonian extension closely follow the pre-existing subduction zone and its associated duplications in the lower orogenic plate. This conclusion is compatible with observations in other areas of the Dinarides, such as the Prosara-Motajica in Bosnia/Croatia or Kopaonik-Studenica in southern Serbia (Schefer et al., 2008; Ustaszewski et al., 2009).
Heating of trapped ultracold atoms by collapse dynamics
NASA Astrophysics Data System (ADS)
Laloë, Franck; Mullin, William J.; Pearle, Philip
2014-11-01
The continuous spontaneous localization (CSL) theory alters the Schrödinger equation. It describes wave-function collapse as a dynamical process instead of an ill-defined postulate, thereby providing macroscopic uniqueness and solving the so-called measurement problem of standard quantum theory. CSL contains a parameter λ giving the collapse rate of an isolated nucleon in a superposition of two spatially separated states and, more generally, characterizing the collapse time for any physical situation. CSL is experimentally testable, since it predicts some behavior different from that predicted by standard quantum theory. One example is the narrowing of wave functions, which results in energy imparted to particles. Here we consider energy given to trapped ultracold atoms. Since these are the coldest samples under experimental investigation, it is worth inquiring how they are affected by the CSL heating mechanism. We examine the CSL heating of a Bose-Einstein condensate (BEC) in contact with its thermal cloud. Of course, other mechanisms also provide heat and also particle loss. From varied data on optically trapped cesium BECs, we present an energy audit for known heating and loss mechanisms. The result provides an upper limit on CSL heating and thereby an upper limit on the parameter λ . We obtain λ ≲1 (±1 ) ×10-7 s-1.
Sukal-Moulton, Theresa; Krosschell, Kristin J; Gaebler-Spira, Deborah J; Dewald, Julius P A
2014-01-01
Extensive neuromotor development occurs early in human life, and the timing of brain injury may affect the resulting motor impairment. In Part I of this series, it was demonstrated that the distribution of weakness in the upper extremity depended on the timing of brain injury in individuals with childhood-onset hemiparesis. The goal of this study was to characterize how timing of brain injury affects joint torque synergies, or losses of independent joint control. Twenty-four individuals with hemiparesis were divided into 3 groups based on the timing of their injury: before birth (PRE-natal, n = 8), around the time of birth (PERI-natal, n = 8), and after 6 months of age (POST-natal, n = 8). Individuals with hemiparesis and 8 typically developing peers participated in maximal isometric shoulder, elbow, wrist, and finger torque generation tasks while their efforts were recorded by a multiple degree-of-freedom load cell. Motor output in 4 joints of the upper extremity was concurrently measured during 8 primary torque generation tasks to quantify joint torque synergies. There were a number of significant coupling patterns identified in individuals with hemiparesis that differed from the typically developing group. POST-natal differences were most noted in the coupling of shoulder abductors with elbow, wrist, and finger flexors, while the PRE-natal group demonstrated significant distal joint coupling with elbow flexion. The torque synergies measured provide indirect evidence for the use of bulbospinal pathways in the POST-natal group, while those with earlier injury may use relatively preserved ipsilateral corticospinal motor pathways.
Diversity waves in collapse-driven population dynamics
Maslov, Sergei; Sneppen, Kim
2015-09-14
Populations of species in ecosystems are often constrained by availability of resources within their environment. In effect this means that a growth of one population, needs to be balanced by comparable reduction in populations of others. In neutral models of biodiversity all populations are assumed to change incrementally due to stochastic births and deaths of individuals. Here we propose and model another redistribution mechanism driven by abrupt and severe collapses of the entire population of a single species freeing up resources for the remaining ones. This mechanism may be relevant e.g. for communities of bacteria, with strain-specific collapses caused e.g.more » by invading bacteriophages, or for other ecosystems where infectious diseases play an important role. The emergent dynamics of our system is cyclic ‘‘diversity waves’’ triggered by collapses of globally dominating populations. The population diversity peaks at the beginning of each wave and exponentially decreases afterwards. Species abundances are characterized by a bimodal time-aggregated distribution with the lower peak formed by populations of recently collapsed or newly introduced species while the upper peak - species that has not yet collapsed in the current wave. In most waves both upper and lower peaks are composed of several smaller peaks. This self-organized hierarchical peak structure has a long-term memory transmitted across several waves. It gives rise to a scale-free tail of the time-aggregated population distribution with a universal exponent of 1.7. We show that diversity wave dynamics is robust with respect to variations in the rules of our model such as diffusion between multiple environments, species-specific growth and extinction rates, and bet-hedging strategies.« less
Diversity waves in collapse-driven population dynamics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Maslov, Sergei; Sneppen, Kim
Populations of species in ecosystems are often constrained by availability of resources within their environment. In effect this means that a growth of one population, needs to be balanced by comparable reduction in populations of others. In neutral models of biodiversity all populations are assumed to change incrementally due to stochastic births and deaths of individuals. Here we propose and model another redistribution mechanism driven by abrupt and severe collapses of the entire population of a single species freeing up resources for the remaining ones. This mechanism may be relevant e.g. for communities of bacteria, with strain-specific collapses caused e.g.more » by invading bacteriophages, or for other ecosystems where infectious diseases play an important role. The emergent dynamics of our system is cyclic ‘‘diversity waves’’ triggered by collapses of globally dominating populations. The population diversity peaks at the beginning of each wave and exponentially decreases afterwards. Species abundances are characterized by a bimodal time-aggregated distribution with the lower peak formed by populations of recently collapsed or newly introduced species while the upper peak - species that has not yet collapsed in the current wave. In most waves both upper and lower peaks are composed of several smaller peaks. This self-organized hierarchical peak structure has a long-term memory transmitted across several waves. It gives rise to a scale-free tail of the time-aggregated population distribution with a universal exponent of 1.7. We show that diversity wave dynamics is robust with respect to variations in the rules of our model such as diffusion between multiple environments, species-specific growth and extinction rates, and bet-hedging strategies.« less
Strand, E; Fjordbakk, C T; Sundberg, K; Spangen, L; Lunde, H; Hanche-Olsen, S
2012-09-01
Two genetically and phenotypically distinct horse breeds are used for harness racing in Scandinavia: the Standardbred (SB) and Coldblooded Trotter. These racehorses have identical environmental, management and racing conditions. Therefore, this study was undertaken to identify and compare the relative prevalence of upper respiratory tract (URT) obstructive disorders in these 2 breeds. To determine whether these 2 phenotypically different breeds of harness racehorses have different predispositions for URT disorders. Retrospective study of 88 Norwegian Coldblooded Trotters (NCT) and 97 SBs referred to this hospital for URT evaluation between 1998 and 2006. Case records of all horses diagnosed with an URT disorder during resting endoscopy, and all horses undergoing high-speed treadmill videoendoscopy (HSTV) with one or more periods of induced poll flexion were evaluated. The relative prevalence of URT disorders between the 2 breeds was analysed using a Fisher's exact test. There was a significant (P<0.05) breed predisposition regarding 6 URT disorders. Bilateral dynamic laryngeal collapse associated with poll flexion and flaccid epiglottis was significantly more frequent in the NCT. Alar fold collapse and nasopharyngeal collapse were significantly more frequent in SBs. Epiglottic entrapment and nasal flutter were only diagnosed in the SBs. Dynamic disorders were more common than resting disorders in both breeds. URT obstructive disorders (dynamic laryngeal collapse associated with poll flexion, flaccid epiglottis, pharyngeal collapse, alar fold collapse, nasal flutter and epiglottic entrapment) are breed related, indicating an anatomic or functional cause. Periods of induced poll flexion during HSTV was essential to declare harness racehorses free of URT disorders. Further anatomic or physiological studies comparing these breeds could potentially provide insight into the pathogenesis of certain URT obstructive disorders. Induced poll flexion should be included in routine HSTV examinations of all harness racehorses. © 2011 EVJ Ltd.
NASA Astrophysics Data System (ADS)
Martínez-Moreno, F. J.; Monteiro Santos, F. A.; Madeira, J.; Pous, J.; Bernardo, I.; Soares, A.; Esteves, M.; Adão, F.; Ribeiro, J.; Mata, J.; Brum da Silveira, A.
2018-05-01
One of the most remarkable natural events on Earth are the large lateral flank collapses of oceanic volcanoes, involving volumes of rock exceeding tens of km3. These collapses are relatively frequent in recent geological times as supported by evidence found in the geomorphology of volcanic island edifices and associated debris flows deposited on the proximal ocean floor. The Island of Fogo in the Cape Verde archipelago is one of the most active and prominent oceanic volcanoes on Earth. The island has an average diameter of 25 km and reaches a maximum elevation of 2829 m above sea level (m a.s.l.) at Pico do Fogo, a young stratovolcano located within a summit depression open eastward due to a large lateral flank collapse. The sudden collapse of the eastern flank of Fogo Island produced a megatsunami 73 ky ago. The limits of the flank collapse were deduced as well from geomorphologic markers within the island. The headwall of the collapse scar is interpreted as either being located beneath the post-collapse volcanic infill of the summit depression or located further west, corresponding to the Bordeira wall that partially surrounds it. The magnetotelluric (MT) method provides a depth distribution of the ground resistivity obtained by the simultaneous measurement of the natural variations of the electric and magnetic field of the Earth. Two N-S magnetotelluric profiles were acquired across the collapsed area to determine its geometry and boundaries. The acquired MT data allowed the determination of the limits of the collapsed area more accurately as well as its morphology at depth and thickness of the post-collapse infill. According to the newly obtained MT data and the bathymetry of the eastern submarine flank of Fogo, the volume involved in the flank collapse is estimated in 110 km3. This volume -the first calculated onshore- stands between the previously published more conservative and excessive calculations -offshore- that were exclusively based in geomorphic evidence. The model for the summit depression proposing two caldera collapses preceding the collapse of the eastern flank of Fogo is supported by the MT data.
Eckmann, R
2015-05-01
A full factorial crossing experiment with five females and five males of each of two coregonid species from upper Lake Constance was used to test for intrinsic post-zygotic incompatibilities during early ontogeny. Up until shortly before hatching, there was no difference in embryo mortality between homo and heterologous crosses. A maternal effect on mortality was found in both species, but paternal effects and female-male interactions were absent. Thus, genetic incompatibility during early ontogeny does not appear to prevent introgressive hybridization, suggesting that genetic divergence between these species is maintained primarily by pre-zygotic barriers. The recent genetic homogenizations of coregonid species flocks in European alpine lakes may have been caused by a flattening of adaptive landscapes through eutrophication, but intensive stocking with larvae obtained in hatcheries from artificially fertilized eggs is also likely to be a contributing factor. To safeguard diversity among sympatric coregonids, it is important to re-establish ecological conditions conducive to species divergence and to revise traditional management strategies. © 2015 The Fisheries Society of the British Isles.
Yin, Chan Wai; Sien, Ng Yee; Ying, Low Ai; Chung, Stephanie Fook-Chong Man; Tan May Leng, Dawn
2014-11-01
To investigate the effect of virtual reality (VR) rehabilitation on upper extremity motor performance of patients with early stroke. Pilot randomized controlled trial. Rehabilitation wards. Twenty three adults with stroke (mean age (SD) = 58.35 (13.45) years and mean time since stroke (SD) = 16.30 (7.44) days). Participants were randomly assigned to VR group (n=11) or control group (n=12). VR group received nine 30 minutes upper extremity VR therapy in standing (five weekdays in two weeks) plus conventional therapy, which included physical and occupational therapy. Control group received only conventional therapy, which was comparable to total training time received by VR group (mean training hours (SD):VR = 17.07 (2.86); control = 15.50 (2.79)). The main outcome measure was the Fugl-Meyer Assessment (FMA). Secondary outcomes included Action Research Arm Test, Motor Activity Log and Functional Independence Measure. Results were taken at baseline, post intervention and 1-month post intervention. Participants' feedback and adverse effects were recorded. All participants improved in FMA scores (mean change (SD) = 11.65 (8.56), P<.001). These effects were sustained at one month after intervention (mean (SD) change from baseline = 18.67 (13.26), P<.001). All other outcome measures showed similar patterns. There were no significant differences in improvement between both groups. Majority of the participants found VR training useful and enjoyable, with no serious adverse effects reported. Although additional VR training was not superior to conventional therapy alone, this study demonstrates the feasibility of VR training in early stroke. © The Author(s) 2014.
El-Chami, Mohamad; Shaheen, David; Ivers, Blake; Syed, Ziauddin; Badr, M Safwan; Lin, Ho-Sheng; Mateika, Jason H
2015-09-15
We investigated if the number and duration of breathing events coupled to upper airway collapsibility were affected by the time of day. Male participants with obstructive sleep apnea completed a constant routine protocol that consisted of sleep sessions in the evening (10 PM to 1 AM), morning (6 AM to 9 AM), and afternoon (2 PM to 5 PM). On one occasion the number and duration of breathing events was ascertained for each sleep session. On a second occasion the critical closing pressure that demarcated upper airway collapsibility was determined. The duration of breathing events was consistently greater in the morning compared with the evening and afternoon during N1 and N2, while an increase in event frequency was evident during N1. The critical closing pressure was increased in the morning (2.68 ± 0.98 cmH2O) compared with the evening (1.29 ± 0.91 cmH2O; P ≤ 0.02) and afternoon (1.25 ± 0.79; P ≤ 0.01). The increase in the critical closing pressure was correlated to the decrease in the baseline partial pressure of carbon dioxide in the morning compared with the afternoon and evening (r = -0.73, P ≤ 0.005). Our findings indicate that time of day affects the duration and frequency of events, coupled with alterations in upper airway collapsibility. We propose that increases in airway collapsibility in the morning may be linked to an endogenous modulation of baseline carbon dioxide levels and chemoreflex sensitivity (12), which are independent of the consequences of sleep apnea.
Improved Noninterferometric Test of Collapse Models Using Ultracold Cantilevers
NASA Astrophysics Data System (ADS)
Vinante, A.; Mezzena, R.; Falferi, P.; Carlesso, M.; Bassi, A.
2017-09-01
Spontaneous collapse models predict that a weak force noise acts on any mechanical system, as a consequence of the collapse of the wave function. Significant upper limits on the collapse rate have been recently inferred from precision mechanical experiments, such as ultracold cantilevers and the space mission LISA Pathfinder. Here, we report new results from an experiment based on a high-Q cantilever cooled to millikelvin temperatures, which is potentially able to improve the current bounds on the continuous spontaneous localization (CSL) model by 1 order of magnitude. High accuracy measurements of the cantilever thermal fluctuations reveal a nonthermal force noise of unknown origin. This excess noise is compatible with the CSL heating predicted by Adler. Several physical mechanisms able to explain the observed noise have been ruled out.
NASA Astrophysics Data System (ADS)
Broughton, Paul L.
2013-01-01
The sub-Cretaceous paleotopography underlying giant Lower Cretaceous Athabasca oil sands, northern Alberta, has an orthogonal lattice pattern of troughs up to 50 km long and 100 m deep between pairs of cross-cutting lineaments. These structures are interpreted to have been inherited from a similar pattern of dissolution collapse-subsidence troughs in the underlying Middle Devonian salt beds. Removal of more than 100 m of halite salt fragmented the overlying Upper Devonian strata into fault blocks and collapse breccias that subsided into the underlying dissolution troughs. The unusually low 1:2 to 1:3 thickness ratios of halite salts to the overlying strata resulted in the Upper Devonian strata collapse-subsidence into underlying salt dissolution troughs being more cataclysmic during the first phase of salt removal. The second phase of slower but complete salt removal between the earlier troughs resulted in a more gradual subsidence of the overlying strata. This obliterated the earlier pattern of giant cross-cutting dissolution troughs bounded by major lineaments. The collapse breccia fabrics underlying the earlier troughs differ from those from areas between the troughs. Collapse breccias underlying the large troughs often have crushed fabrics distributed in zones that rapidly pinched out between fault blocks. Breccias between troughs developed as giant mosaics of detached carbonate blocks that formed breccia pipe complexes. Multiple sinkholes up to 100 m deep aligned along multi-km linear valley trends that dissected the sub-Cretaceous paleotopography. These sinkhole trends formed orthogonal patterns inherited from underlying lattice of NW-SE and NE-SW salt structured lineaments. These cross-cutting sinkhole trends have a smaller 5 km scale reticulate pattern similar to the giant 50 km scale pattern of collapse-subsidence troughs. Other sinkholes developed as lower McMurray strata sagged when underlying Devonian fault blocks and breccia pipes differentially subsided.
NASA Astrophysics Data System (ADS)
Cornu, Melodie-Neige; Paris, Raphael; Doucelance, Regis; Bachelery, Patrick; Guillou, Hervé
2017-04-01
Mass wasting of oceanic shield volcanoes is largely documented through the recognition of collapse scars and submarine debris fans. However, it is actually difficult to infer the mechanisms controlling volcano flank failures that potentially imply tens to hundreds of km3. Studies coupling detailed petrological and geochemical analyses of eruptive products hold clues for better understanding the relationships between magma sources, the plumbing system, and flank instability. Our study aims at tracking potential variations of magma source, storage and transport beneath Fogo shield volcano (Cape Verde) before and after its major flank collapse. We also provide a geochronological framework of this magmatic evolution through new radiometric ages (K-Ar and Ar-Ar) of both pre-collapse and post-collapse lavas. The central part of Fogo volcanic edifice is truncated by an 8 km-wide caldera opened to the East, corresponding to the scar of the last flank collapse (Monte Amarelo collapse, Late Pleistocene, 150 km3). Lavas sampled at the base of the scar (the so-called Bordeira) yielded ages between 158 and 136 ka. The age of the collapse is constrained between 68 ka (youngest lava flow cut by the collapse scar) and 59 ka (oldest lava flow overlapping the scar). The collapse walls display a complex structural, intrusive and eruptive history. Undersaturated volcanism (SiO2<43%) is surprisingly dominated by explosive products such as ignimbrites, with 4 major explosive episodes representing half of the volume of the central edifice. This explosive record onshore is correlated with the offshore record of mafic tephra and turbidites (Eisele et al., 2015). Major elements analyses indicate that the pre-collapse lavas are significantly less differentiated than post-collapse lavas, with a peak of alkalis at the collapse. Rare-earth elements concentration decreases with time, with a notable positive anomaly before the collapse. The evolution of the isotopic ratios (Sr, Nd and Pb) through time displays unusual V-shaped profiles centered around the collapse. The occurrence of the Monte Amarelo collapse is thus not disconnected from the magmatic evolution, both at the crustal and mantellic levels. Our results also point out the importance and relative frequency of explosive eruptions of undersaturated magmas at Fogo volcano.
First Early Hominin from Central Africa (Ishango, Democratic Republic of Congo)
Crevecoeur, Isabelle; Skinner, Matthew M.; Bailey, Shara E.; Gunz, Philipp; Bortoluzzi, Silvia; Brooks, Alison S.; Burlet, Christian; Cornelissen, Els; De Clerck, Nora; Maureille, Bruno; Semal, Patrick; Vanbrabant, Yves; Wood, Bernard
2014-01-01
Despite uncontested evidence for fossils belonging to the early hominin genus Australopithecus in East Africa from at least 4.2 million years ago (Ma), and from Chad by 3.5 Ma, thus far there has been no convincing evidence of Australopithecus, Paranthropus or early Homo from the western (Albertine) branch of the Rift Valley. Here we report the discovery of an isolated upper molar (#Ish25) from the Western Rift Valley site of Ishango in Central Africa in a derived context, overlying beds dated to between ca. 2.6 to 2.0 Ma. We used µCT imaging to compare its external and internal macro-morphology to upper molars of australopiths, and fossil and recent Homo. We show that the size and shape of the enamel-dentine junction (EDJ) surface discriminate between Plio-Pleistocene and post-Lower Pleistocene hominins, and that the Ishango molar clusters with australopiths and early Homo from East and southern Africa. A reassessment of the archaeological context of the specimen is consistent with the morphological evidence and suggest that early hominins were occupying this region by at least 2 Ma. PMID:24427292
NASA Astrophysics Data System (ADS)
Bolliet, Timothé; Holbourn, Ann; Kuhnt, Wolfgang; Laj, Carlo; Kissel, Catherine; Beaufort, Luc; Kienast, Markus; Andersen, Nils; Garbe-Schönberg, Dieter
2011-02-01
We present sea surface, upper thermocline, and benthic δ18O data, as well as temperature and paleoproductivity proxy data, from the International Marine Global Change Study Program (IMAGES) Core MD06-3067 (6°31‧N, 126°30‧E, 1575 m water depth), located in the western equatorial Pacific Ocean within the flow path of the Mindanao Current. Our records reveal considerable glacial-interglacial and suborbital variability in the Mindanao Dome upwelling over the last 160 kyr. Dome activity generally intensified during glacial intervals resulting in cooler thermocline waters, whereas it substantially declined during interglacials, in particular in the early Holocene and early marine oxygen isotope stage (MIS) 5e, when upwelling waters did not reach the thermocline. During MIS 3 and MIS 2, enhanced surface productivity together with remarkably low SST and low upper ocean thermal contrast provide evidence for episodic glacial upwelling to the surface, whereas transient surface warming marks periodic collapses of the Mindanao Dome upwelling during Heinrich events. We attribute the high variability during MIS 3 and MIS 2 to changes in the El Niño Southern Oscillation state that affected boreal winter monsoonal winds and upper ocean circulation. Glacial upwelling intensified when a strong cyclonic gyre became established, whereas El Niño-like conditions during Heinrich events tended to suppress the cyclonic circulation, reducing Ekman transport. Thus, our findings demonstrate that variations in the Mindanao Dome upwelling are closely linked to the position and intensity of the tropical convection and also reflect far-field influences from the high latitudes.
Characteristic microwave background distortions from collapsing domain wall bubbles
NASA Technical Reports Server (NTRS)
Goetz, Guenter; Noetzold, Dirk
1990-01-01
The magnitude and angular pattern of distortions of the microwave background are analyzed by collapsing spherical domain walls. A characteristic pattern of redshift distortions of red or blue spikes surrounded by blue discs was found. The width and height of a spike is related to the diameter and magnitude of the disc. A measurement of the relations between these quantities thus can serve as an unambiguous indicator for a collapsing spherical domain wall. From the redshift distortion in the blue discs an upper bound was found on the surface energy density of the walls sigma is less than or approximately 8 MeV cubed.
Engstrom, Eric J; Burgmair, Wolfgang; Weber, Matthias M
2016-06-01
This is the second of two articles exploring in depth some of the early organizational strategies that were marshalled in efforts to found and develop the German Research Institute of Psychiatry (Deutsche Forschungsanstalt für Psychiatrie). The first article analysed the strategies of psychiatric governance - best understood as a form of völkisch corporatism - that mobilized a group of stakeholders in the service of higher bio-political and hygienic ends. This second article examines how post-war imperatives and biopolitical agendas shaped the institute's organization and research. It also explores the financial challenges the institute faced amidst the collapse of the German financial system in the early Weimar Republic, including efforts to recruit financial support from the Rockefeller Foundation and other philanthropists in the USA. © The Author(s) 2016.
The Conceptual History of Independence and the Colonial Question in Spanish America.
Ortega, Francisco A
2018-01-01
The idea that Spanish American countries experienced colonialism was well accepted for most of the nineteenth and twentieth centuries. The independence movements in the early nineteenth century were viewed as the result of struggles by oppressed nations against the metropole's tyranny. Recent historiography views the collapse of the monarchy as the result of the political and legal crisis brought about by the Napoleonic invasion and the illegal abdications in Bayonne in March 1808. Colonial and post-colonial theories and categories have been brought under scrutiny. The following pages sketch the historiographical and theoretical grounds and consequences of this paradigm shift.
New Insights into Passive Margin Development from a Global Deep Seismic Reflection Dataset
NASA Astrophysics Data System (ADS)
Bellingham, Paul; Pindell, James; Graham, Rod; Horn, Brian
2014-05-01
The kinematic and dynamic evolution of the world's passive margins is still poorly understood. Yet the need to replace reserves, a high oil price and advances in drilling technology have pushed the international oil and gas industry to explore in the deep and ultra-deep waters of the continental margins. To support this exploration and help understand these margins, ION-GXT has acquired, processed and interpreted BasinSPAN surveys across many of the world's passive margins. Observations from these data lead us to consider the modes of subsidence and uplift at both volcanic and non-volcanic margins. At non-volcanic margins, it appears that frequently much of the subsidence post-dates major rifting and is not thermal in origin. Rather the subsidence is associated with extensional displacement on a major fault or shear zone running at least as deep as the continental Moho. We believe that the subsidence is structural and is probably associated with the pinching out (boudinage) of the Lower Crust so that the Upper crust effectively collapses onto the mantle. Eventually this will lead to the exhumation of the sub-continental mantle at the sea bed. Volcanic margins present more complex challenges both in terms of imaging and interpretation. The addition of volcanic and plutonic material into the system and dynamic effects all impact subsidence and uplift. However, we will show some fundamental observations regarding the kinematic development of volcanic margins and especially SDRs which demonstate that the process of collapse and the development of shear zones within and below the crust are also in existence at this type of margin. A model is presented of 'magma welds' whereby packages of SDRs collapse onto an emerging sub-crustal shear zone and it is this collapse which creates the commonly observed SDR geometry. Examples will be shown from East India, Newfoundland, Brazil, Argentina and the Gulf of Mexico.
The upper airway in sleep-disordered breathing: UA in SDB.
Taranto Montemurro, L; Kasai, T
2014-02-01
Sleep disordered breathing (SDB) is a common condition and could be a risk factor for cardiovascular morbidity and mortality. However, the pathogenesis of SDB remains to be elucidated. In general, SDB is divided into two forms, obstructive and central sleep apnea (OSA and CSA, respectively). OSA results from the sleep-related collapse of the upper airway (UA) in association with multiple factors like race, gender, obesity and UA dimensions. CSA primarily results from a fall in PaCO2 to a level below the apnea threshold during sleep through the reflex inhibition of central respiratory drive. It has been reported that UA alterations (i.e., collapse or dilation) can be observed in CSA. This review highlights the roles of the UA in the pathogenesis and pathophysiology of SDB.
Kinematic fingerprint of core-collapsed globular clusters
NASA Astrophysics Data System (ADS)
Bianchini, P.; Webb, J. J.; Sills, A.; Vesperini, E.
2018-03-01
Dynamical evolution drives globular clusters towards core collapse, which strongly shapes their internal properties. Diagnostics of core collapse have so far been based on photometry only, namely on the study of the concentration of the density profiles. Here, we present a new method to robustly identify core-collapsed clusters based on the study of their stellar kinematics. We introduce the kinematic concentration parameter, ck, the ratio between the global and local degree of energy equipartition reached by a cluster, and show through extensive direct N-body simulations that clusters approaching core collapse and in the post-core collapse phase are strictly characterized by ck > 1. The kinematic concentration provides a suitable diagnostic to identify core-collapsed clusters, independent from any other previous methods based on photometry. We also explore the effects of incomplete radial and stellar mass coverage on the calculation of ck and find that our method can be applied to state-of-art kinematic data sets.
Yoshizaki, Tetsuya; Obata, Daisuke; Aoki, Yasuhiro; Okamoto, Norihiro; Hashimura, Hiroki; Kano, Chise; Matsushita, Megumi; Kanamori, Atsushi; Matsumoto, Kei; Tsujimae, Masahiro; Momose, Kenji; Eguchi, Takaaki; Okuyama, Shunsuke; Yamashita, Hiroshi; Fujita, Mikio; Okada, Akihiko
2018-02-07
Advances in Endoscopic submucosal dissection (ESD) technology have established ESD for early gastric cancer as a safe and stable technique. However, ESD may induce delayed gastric emptying and the cause of food residue retention in the stomach after ESD is not clear. This study aimed to clarify risk factors for delayed gastric emptying with food retention after gastric ESD. We retrospectively examined for food residue in the stomach 1 week after ESD was performed for early gastric carcinoma at Osaka Saiseikai Nakatsu Hospital from February 2008 to November 2016. Food residue was observed in 68 (6.1%) of 1114 patients who underwent gastric ESD. The percentage of lesions located on the lesser curvature of the upper third of the stomach was 45.6% (31/68) in the food residue group and 3.5% (37/1046) in the non-food residue group, which was significantly different (P < 0.01). Multivariate logistic regression analysis revealed that lesions on the lesser curvature of the upper third of the stomach (Odds ratio [OR] 23.31, 95% confidence interval [CI] 12.60-43.61, P < 0.01), post-ESD bleeding (OR 4.25, 95%CI 1.67-9.80, P < 0.01), submucosal invasion (OR 2.80, 95%CI 1.34-5.63, P < 0.01), and age over 80 years (OR 2.34, 95%CI 1.28-4.22, P < 0.01) were independent risk factors for food retention after gastric ESD. Of the 68 patients, 3 had food residue in the stomach on endoscopic examination for follow-up observation after the ESD ulcer had healed. Delayed gastric emptying with food retention after gastric ESD was associated with lesions located in the lesser curvature of the upper stomach, submucosal invasion of the lesion, age older than 80 years, and post-ESD bleeding, though it was temporary in most cases.
Davidson, E J; Martin, B B; Boston, R C; Parente, E J
2011-01-01
Although well documented in racehorses, there is paucity in the literature regarding the prevalence of dynamic upper airway abnormalities in nonracing performance horses. To describe upper airway function of nonracing performance horses with abnormal respiratory noise and/or poor performance via exercising upper airway videoendoscopy. Medical records of nonracing performance horses admitted for exercising evaluation with a chief complaint of abnormal respiratory noise and/or poor performance were reviewed. All horses had video recordings of resting and exercising upper airway endoscopy. Relationships between horse demographics, resting endoscopic findings, treadmill intensity and implementation of head and neck flexion during exercise with exercising endoscopic findings were examined. Dynamic upper airway obstructions were observed in 72% of examinations. Head and neck flexion was necessary to obtain a diagnosis in 21 horses. Pharyngeal wall collapse was the most prevalent upper airway abnormality, observed in 31% of the examinations. Complex abnormalities were noted in 27% of the examinations. Resting laryngeal dysfunction was significantly associated with dynamic arytenoid collapse and the odds of detecting intermittent dorsal displacement of the soft palate (DDSP) during exercise in horses with resting DDSP was only 7.7%. Exercising endoscopic observations were different from the resting observations in 54% of examinations. Dynamic upper airway obstructions were common in nonracing performance horses with respiratory noise and/or poor performance. Resting endoscopy was only helpful in determining exercising abnormalities with recurrent laryngeal neuropathy. This study emphasises the importance of exercising endoscopic evaluation in nonracing performance horses with abnormal respiratory noise and/or poor performance for accurate assessment of dynamic upper airway function. © 2010 EVJ Ltd.
Collapse Mechanisms Of Masonry Structures
NASA Astrophysics Data System (ADS)
Zuccaro, G.; Rauci, M.
2008-07-01
The paper outlines a possible approach to typology recognition, safety check analyses and/or damage measuring taking advantage by a multimedia tool (MEDEA), tracing a guided procedure useful for seismic safety check evaluation and post event macroseismic assessment. A list of the possible collapse mechanisms observed in the post event surveys on masonry structures and a complete abacus of the damages are provided in MEDEA. In this tool a possible combination between a set of damage typologies and each collapse mechanism is supplied in order to improve the homogeneity of the damages interpretation. On the other hand recent researches of one of the author have selected a number of possible typological vulnerability factors of masonry buildings, these are listed in the paper and combined with potential collapse mechanisms to be activated under seismic excitation. The procedure takes place from simple structural behavior models, derived from the Umbria-Marche earthquake observations, and tested after the San Giuliano di Puglia event; it provides the basis either for safety check analyses of the existing buildings or for post-event structural safety assessment and economic damage evaluation. In the paper taking advantage of MEDEA mechanisms analysis, mainly developed for the post event safety check surveyors training, a simple logic path is traced in order to approach the evaluation of the masonry building safety check. The procedure starts from the identification of the typological vulnerability factors to derive the potential collapse mechanisms and their collapse multipliers and finally addresses the simplest and cheapest strengthening techniques to reduce the original vulnerability. The procedure has been introduced in the Guide Lines of the Regione Campania for the professionals in charge of the safety check analyses and the buildings strengthening in application of the national mitigation campaign introduced by the Ordinance of the Central Government n. 3362/03. The main cases of out of plane mechanisms are analyzed and a possible innovative theory for masonry building vulnerability assessment, based on limit state analyses, is outlined. The paper report the first step of a research granted by the Department of the Civil Protection to Reluis within the research program of Line 10.
Collapse Mechanisms Of Masonry Structures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zuccaro, G.; Rauci, M.
2008-07-08
The paper outlines a possible approach to typology recognition, safety check analyses and/or damage measuring taking advantage by a multimedia tool (MEDEA), tracing a guided procedure useful for seismic safety check evaluation and post event macroseismic assessment. A list of the possible collapse mechanisms observed in the post event surveys on masonry structures and a complete abacus of the damages are provided in MEDEA. In this tool a possible combination between a set of damage typologies and each collapse mechanism is supplied in order to improve the homogeneity of the damages interpretation. On the other hand recent researches of onemore » of the author have selected a number of possible typological vulnerability factors of masonry buildings, these are listed in the paper and combined with potential collapse mechanisms to be activated under seismic excitation. The procedure takes place from simple structural behavior models, derived from the Umbria-Marche earthquake observations, and tested after the San Giuliano di Puglia event; it provides the basis either for safety check analyses of the existing buildings or for post-event structural safety assessment and economic damage evaluation. In the paper taking advantage of MEDEA mechanisms analysis, mainly developed for the post event safety check surveyors training, a simple logic path is traced in order to approach the evaluation of the masonry building safety check. The procedure starts from the identification of the typological vulnerability factors to derive the potential collapse mechanisms and their collapse multipliers and finally addresses the simplest and cheapest strengthening techniques to reduce the original vulnerability. The procedure has been introduced in the Guide Lines of the Regione Campania for the professionals in charge of the safety check analyses and the buildings strengthening in application of the national mitigation campaign introduced by the Ordinance of the Central Government n. 3362/03. The main cases of out of plane mechanisms are analyzed and a possible innovative theory for masonry building vulnerability assessment, based on limit state analyses, is outlined. The paper report the first step of a research granted by the Department of the Civil Protection to Reluis within the research program of Line 10.« less
Low-(18)O Silicic Magmas: Why Are They So Rare?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Balsley, S.D.; Gregory, R.T.
1998-10-15
LOW-180 silicic magmas are reported from only a small number of localities (e.g., Yellowstone and Iceland), yet petrologic evidence points to upper crustal assimilation coupled with fractional crystallization (AFC) during magma genesis for nearly all silicic magmas. The rarity of 10W-l `O magmas in intracontinental caldera settings is remarkable given the evidence of intense 10W-l*O meteoric hydrothermal alteration in the subvolcanic remnants of larger caldera systems. In the Platoro caldera complex, regional ignimbrites (150-1000 km3) have plagioclase 6180 values of 6.8 + 0.1%., whereas the Middle Tuff, a small-volume (est. 50-100 km3) post-caldera collapse pyroclastic sequence, has plagioclase 8]80 valuesmore » between 5.5 and 6.8%o. On average, the plagioclase phenocrysts from the Middle Tuff are depleted by only 0.3%0 relative to those in the regional tuffs. At Yellowstone, small-volume post-caldera collapse intracaldera rhyolites are up to 5.5%o depleted relative to the regional ignimbrites. Two important differences between the Middle Tuff and the Yellowstone 10W-180 rhyolites elucidate the problem. Middle Tuff magmas reached water saturation and erupted explosively, whereas most of the 10W-l 80 Yellowstone rhyolites erupted effusively as domes or flows, and are nearly devoid of hydrous phenocrysts. Comparing the two eruptive types indicates that assimilation of 10W-180 material, combined with fractional crystallization, drives silicic melts to water oversaturation. Water saturated magmas either erupt explosively or quench as subsurface porphyrins bejiire the magmatic 180 can be dramatically lowered. Partial melting of low- 180 subvolcanic rocks by near-anhydrous magmas at Yellowstone produced small- volume, 10W-180 magmas directly, thereby circumventing the water saturation barrier encountered through normal AFC processes.« less
Upper Airway Collapsibility During REM Sleep in Children with the Obstructive Sleep Apnea Syndrome
Huang, Jingtao; Karamessinis, Laurie R.; Pepe, Michelle E.; Glinka, Stephen M.; Samuel, John M.; Gallagher, Paul R.; Marcus, Carole L.
2009-01-01
Study Objectives: In children, most obstructive events occur during rapid eye movement (REM) sleep. We hypothesized that children with the obstructive sleep apnea syndrome (OSAS), in contrast to age-matched control subjects, would not maintain airflow in the face of an upper airway inspiratory pressure drop during REM sleep. Design: During slow wave sleep (SWS) and REM sleep, we measured airflow, inspiratory time, inspiratory time/total respiratory cycle time, respiratory rate, tidal volume, and minute ventilation at a holding pressure at which flow limitation occurred and at 5 cm H2O below the holding pressure in children with OSAS and in control subjects. Setting: Sleep laboratory. Participants: Fourteen children with OSAS and 23 normal control subjects. Results: In both sleep states, control subjects were able to maintain airflow, whereas subjects with OSAS preserved airflow in SWS but had a significant decrease in airflow during REM sleep (change in airflow of 18.58 ± 12.41 mL/s for control subjects vs −44.33 ± 14.09 mL/s for children with OSAS, P = 0.002). Although tidal volume decreased, patients with OSAS were able to maintain minute ventilation by increasing the respiratory rate and also had an increase in inspiratory time and inspiratory time per total respiratory cycle time Conclusion: Children with OSAS do not maintain airflow in the face of upper-airway inspiratory-pressure drops during REM sleep, indicating a more collapsible upper airway, compared with that of control subjects during REM sleep. However, compensatory mechanisms exist to maintain minute ventilation. Local reflexes, central control mechanisms, or both reflexes and control mechanisms need to be further explored to better understand the pathophysiology of this abnormality and the compensation mechanism. Citation: Huang J; Karamessinis LR; Pepe ME; Glinka SM; Samuel JM; Gallagher PR; Marcus CL. Upper airway collapsibility during REM sleep in children with the obstructive sleep apnea syndrome. SLEEP 2009;32(9):1173-1181. PMID:19750922
Influence of Gender and Age on Upper-Airway Length During Development
Ronen, Ohad; Malhotra, Atul; Pillar, Giora
2008-01-01
OBJECTIVE Obstructive sleep apnea has a strong male predominance in adults but not in children. The collapsible portion of the upper airway is longer in adult men than in women (a property that may increase vulnerability to collapse during sleep). We sought to test the hypothesis that in prepubertal children, pharyngeal airway length is equal between genders, but after puberty boys have a longer upper airway than girls, thus potentially contributing to this change in apnea propensity. METHODS Sixty-nine healthy boys and girls who had undergone computed tomography scans of their neck for other reasons were selected from the computed tomography archives of Rambam and Carmel hospitals. The airway length was measured in the midsagittal plane and defined as the length between the lower part of the posterior hard palate and the upper limit of the hyoid bone. Airway length and normalized airway length/body height were compared between the genders in prepubertal (4- to 10-year-old) and postpubertal (14- to 19-year-old) children. RESULTS In prepubertal children, airway length was similar between boys and girls (43.2 ± 5.9 vs 46.8 ± 7.7 mm, respectively). When normalized to body height, airway length/body height was significantly shorter in prepubertal boys than in girls (0.35 ± 0.03 vs 0.38 ± 0.04 mm/cm). In contrast, postpubertal boys had longer upper airways (66.5 ± 9.2 vs 52.2 ± 7.0 mm) and normalized airway length/body height (0.38 ± 0.05 vs 0.33 ± 0.05 mm/cm) than girls. CONCLUSIONS Although boys have equal or shorter airway length compared with girls among prepubertal children, after puberty, airway length and airway length normalized for body height are significantly greater in boys than in girls. These data suggest that important anatomic changes at puberty occur in a gender-specific manner, which may be important in explaining the male predisposition to pharyngeal collapse in adults. PMID:17908723
NASA Technical Reports Server (NTRS)
2005-01-01
24 April 2005 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a large and several small pits formed by collapse along the trend of a fault system in the Uranius Fossae region of Mars. Running diagonal from middle-right toward lower left is a trough that intersects the pit. The trough is a typical graben formed by faulting as the upper crust of Mars split and pulled apart at this location. The opening of the graben also led to formation of the collapse pits. Location near: 26.2oN, 88.7oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Northern SummerThompson, George A.; Parsons, Thomas E.
2016-01-01
Vertical deformation of extensional provinces varies significantly and in seemingly contradictory ways. Sparse but robust geodetic, seismic, and geologic observations in the Basin and Range province of the western United States indicate that immediately after an earthquake, vertical change primarily occurs as subsidence of the normal fault hanging wall. A few decades later, a ±100 km wide zone is symmetrically uplifted. The preserved topography of long-term rifting shows bent and tilted footwall flanks rising high above deep basins. We develop finite element models subjected to extensional and gravitational forces to study time-varying deformation associated with normal faulting. We replicate observations with a model that has a weak upper mantle overlain by a stronger lower crust and a breakable elastic upper crust. A 60° dipping normal fault cuts through the upper crust and extends through the lower crust to simulate an underlying shear zone. Stretching the model under gravity demonstrates that asymmetric slip via collapse of the hanging wall is a natural consequence of coseismic deformation. Focused flow in the upper mantle imposed by deformation of the lower crust localizes uplift under the footwall; the breakable upper crust is a necessary model feature to replicate footwall bending over the observed width ( < 10 km), which is predicted to take place within 1-2 decades after each large earthquake. Thus the best-preserved topographic signature of rifting is expected to occur early in the postseismic period. The relatively stronger lower crust in our models is necessary to replicate broader postseismic uplift that is observed geodetically in subsequent decades.
Geochemical Evolution of Pre-caldera Magmas at Caviahue Caldera, Neuquen Province, Argentina
NASA Astrophysics Data System (ADS)
Todd, E.; Ort, M.
2004-12-01
Caldera subsidence and glacial erosion at Caviahue, an upper Miocene to Pliocene volcanic center located in the Andean Southern Volcanic Zone (SVZ) at 37°50'S, has exposed a detailed cross-section of pre-caldera volcanic activity from the upper Miocene to the Pliocene. Caldera walls expose 500 to 800 m of ignimbrites, cinder cones, volcanic breccias, and lava flows, which range from 1 to nearly 100 m in thickness. Lavas erupted from the monogenetic pre-caldera volcanic field have compositions ranging from evolved basaltic andesites (4% MgO, 10% FeO) to trachytes. Strong Ni-depletion signatures and high Fe/Mg ratios indicate extensive geochemical modification of Caviahue lavas. Petrologic and geochemical analyses of major and trace element abundances in Caviahue lavas indicate cyclic fractionation and recharge in an upper-crustal magma chamber during pre-caldera volcanism. Compatible and incompatible element abundances (especially Ni, MgO, K, and Zr), plotted in stratigraphic succession, show at least six distinct fractionation trends occurred between emplacement of the oldest exposed lava flows and the eruption of the ignimbrite associated with caldera formation. Each fractionation trend is punctuated by the infusion of a volume of new, more primitive magma. Modeling of recharge events indicates that these introduced from less than half to several times the volume of the existing magma body of new, more primitive (but still evolved) magma to the chamber. Geochemical analyses of lavas deposited between intermittent periods of magma residence and volcanic eruptions show strong patterns of plagioclase, olivine, clinopyroxene, and oxide fractionation. Deposits recognized on the caldera floor thought to be associated with caldera collapse are correlated with extra-caldera trachytic ignimbrite deposits dated at 2.02 Ma, providing a late Pliocene age for caldera collapse. Post-caldera volcanism has been active until present, but has shifted to smaller polygenetic volcanic centers on the periphery of the Caviahue Caldera with the majority of volcanic activity at the historically active Volcán Copahue, located on the western rim of the caldera.
Radiological factors affecting post-operative global coronal balance in Lenke 5 C scoliosis.
Shetty, Ajoy Prasad; Suresh, Subramani; Aiyer, Siddharth N; Kanna, Rishi; Rajasekaran, Shanmuganathan
2017-12-01
Lenke 5 C curves are frequently associated with clinically and radiological coronal imbalance. Appropriate selection of proximal and distal levels of fusion is essential to ensure good coronal balance (CB). We aimed to evaluate radiological factors associated with (I) global CB in the early post-operative period; (II) late decompensation of CB; and (III) favourable spontaneous correction of CB on long term follow up. Twenty-three Lenke type 5C scoliosis cases treated with selective posterior lumbar instrumentation were retrospectively evaluated. Pre-operative, early post-operative and late post-operative (>2 years) whole length radiographs were analysed. Cobb's angle, lumbar lordosis, coronal imbalance, lower instrumented vertebra (LIV) tilt and translation and upper instrumented vertebra (UIV) tilt and translation were measured. The proximal and distal fusion levels were noted and correlated with post-operative CB. There were 21 females and 2 males with a mean follow up of 36 months. The mean pre-operative cobb angle was 55°±13.26°, which corrected to 14.7°±8.84° and was maintained on follow up. Eight patients had early post-operative coronal imbalance with spontaneous resolution seen in six cases on long term follow-up. At final follow-up, four cases had coronal imbalance (persistent imbalance since early post-operative period =2; late decompensation =2). In cases with early imbalance 5/8 cases had a pre-operative LIV tilt of ≥25°. All four patients with coronal imbalance at final follow-up had pre-operative LIV tilt ≥25°. Radiographic parameters which correlated with post-operative coronal imbalance were pre-operative LIV tilt (r=0.64, P=0.001), pre-operative LIV translation (r=0.696, P<0.001), pre-operative UIV translation (r=0.44, P=0.030), post-operative LIV tilt (r=0.804, P<0.001), and post-operative UIV tilt (r=0.62, P=0.001). In Lenke 5C scoliosis, a pre-operative LIV tilt ≥25° significantly correlates with post-operative global coronal imbalance. Increasing UIV tilt may be a factor that accounts for improvement of CB in late follow-up period.
Radiological factors affecting post-operative global coronal balance in Lenke 5 C scoliosis
Suresh, Subramani; Aiyer, Siddharth N.; Kanna, Rishi; Rajasekaran, Shanmuganathan
2017-01-01
Background Lenke 5 C curves are frequently associated with clinically and radiological coronal imbalance. Appropriate selection of proximal and distal levels of fusion is essential to ensure good coronal balance (CB). We aimed to evaluate radiological factors associated with (I) global CB in the early post-operative period; (II) late decompensation of CB; and (III) favourable spontaneous correction of CB on long term follow up. Methods Twenty-three Lenke type 5C scoliosis cases treated with selective posterior lumbar instrumentation were retrospectively evaluated. Pre-operative, early post-operative and late post-operative (>2 years) whole length radiographs were analysed. Cobb’s angle, lumbar lordosis, coronal imbalance, lower instrumented vertebra (LIV) tilt and translation and upper instrumented vertebra (UIV) tilt and translation were measured. The proximal and distal fusion levels were noted and correlated with post-operative CB. Results There were 21 females and 2 males with a mean follow up of 36 months. The mean pre-operative cobb angle was 55°±13.26°, which corrected to 14.7°±8.84° and was maintained on follow up. Eight patients had early post-operative coronal imbalance with spontaneous resolution seen in six cases on long term follow-up. At final follow-up, four cases had coronal imbalance (persistent imbalance since early post-operative period =2; late decompensation =2). In cases with early imbalance 5/8 cases had a pre-operative LIV tilt of ≥25°. All four patients with coronal imbalance at final follow-up had pre-operative LIV tilt ≥25°. Radiographic parameters which correlated with post-operative coronal imbalance were pre-operative LIV tilt (r=0.64, P=0.001), pre-operative LIV translation (r=0.696, P<0.001), pre-operative UIV translation (r=0.44, P=0.030), post-operative LIV tilt (r=0.804, P<0.001), and post-operative UIV tilt (r=0.62, P=0.001). Conclusions In Lenke 5C scoliosis, a pre-operative LIV tilt ≥25° significantly correlates with post-operative global coronal imbalance. Increasing UIV tilt may be a factor that accounts for improvement of CB in late follow-up period. PMID:29354729
Eckert, Danny J.; Malhotra, Atul; Wellman, Andrew; White, David P.
2014-01-01
Study Objectives: The effect of common sedatives on upper airway physiology and breathing during sleep in obstructive sleep apnea (OSA) has been minimally studied. Conceptually, certain sedatives may worsen OSA in some patients. However, sleep and breathing could improve with certain sedatives in patients with OSA with a low respiratory arousal threshold. This study aimed to test the hypothesis that trazodone increases the respiratory arousal threshold in patients with OSA and a low arousal threshold. Secondary aims were to examine the effects of trazodone on upper airway dilator muscle activity, upper airway collapsibility, and breathing during sleep. Design: Patients were studied on 4 separate nights according to a within-subjects cross-over design. Setting: Sleep physiology laboratory. Patients: Seven patients with OSA and a low respiratory arousal threshold. Interventions: In-laboratory polysomnograms were obtained at baseline and after 100 mg of trazodone was administered, followed by detailed overnight physiology experiments under the same conditions. During physiology studies, continuous positive airway pressure was transiently lowered to measure arousal threshold (negative epiglottic pressure prior to arousal), dilator muscle activity (genioglossus and tensor palatini), and upper airway collapsibility (Pcrit). Measurements and Results: Trazodone increased the respiratory arousal threshold by 32 ± 6% (-11.5 ± 1.4 versus -15.3 ± 2.2 cmH2O, P < 0.01) but did not alter the apnea-hypopnea index (39 ± 12 versus 39 ± 11 events/h sleep, P = 0.94). Dilator muscle activity and Pcrit also did not systematically change with trazodone. Conclusions: Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold without major impairment in dilator muscle activity or upper airway collapsibility. However, the magnitude of change in arousal threshold was insufficient to overcome the compromised upper airway anatomy in these patients. Citation: Eckert DJ; Malhotra A; Wellman A; White DP. Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold. SLEEP 2014;37(4):811-819. PMID:24899767
Including trait-based early warning signals helps predict population collapse
Clements, Christopher F.; Ozgul, Arpat
2016-01-01
Foreseeing population collapse is an on-going target in ecology, and this has led to the development of early warning signals based on expected changes in leading indicators before a bifurcation. Such signals have been sought for in abundance time-series data on a population of interest, with varying degrees of success. Here we move beyond these established methods by including parallel time-series data of abundance and fitness-related trait dynamics. Using data from a microcosm experiment, we show that including information on the dynamics of phenotypic traits such as body size into composite early warning indices can produce more accurate inferences of whether a population is approaching a critical transition than using abundance time-series alone. By including fitness-related trait information alongside traditional abundance-based early warning signals in a single metric of risk, our generalizable approach provides a powerful new way to assess what populations may be on the verge of collapse. PMID:27009968
NASA Astrophysics Data System (ADS)
Vezzoli, Luigina; Corazzato, Claudia
2016-05-01
In the upper part of the Stromboli volcano, in the Le Croci and Bastimento areas, two dyke-like bodies of volcanic breccia up to two-metre thick crosscut and intrude the products of Vancori and Neostromboli volcanoes. We describe the lithofacies association of these unusual volcaniclastic dykes, interpret the setting of dyke-forming fractures and the emplacement mechanism of internal deposits, and discuss their probable relationships with the explosive eruption and major lateral collapse events that occurred at the end of the Neostromboli period. The dyke volcaniclastic deposits contain juvenile magmatic fragments (pyroclasts) suggesting a primary volcanic origin. Their petrographic characteristics are coincident with the Neostromboli products. The architecture of the infilling deposits comprises symmetrically-nested volcaniclastic units, separated by sub-vertical boundaries, which are parallel to the dyke margins. The volcanic units are composed of distinctive lithofacies. The more external facies is composed of fine and coarse ash showing sub-vertical laminations, parallel to the contact wall. The central facies comprises stratified, lithic-rich breccia and lapilli-tuff, whose stratification is sub-horizontal and convolute, discordant to the dyke margins. Only at Le Croci dyke, the final unit shows a massive tuff-breccia facies. The volcaniclastic dykes experienced a polyphasic geological evolution comprising three stages. The first phase consisted in fracturing, explosive intrusion related to magma rising and upward injection of magmatic fluids and pyroclasts. The second phase recorded the dilation of fractures and their role as pyroclastic conduits in an explosive eruption possibly coeval with the lateral collapse of the Neostromboli lava cone. Finally, in the third phase, the immediately post-eruption mass-flow remobilization of pyroclastic deposits took place on the volcano slopes.
NASA Astrophysics Data System (ADS)
Huang, Da; Gu, Dong Ming
2017-10-01
The upper Wu Gorge on the Yangtze River has been the site of tens of reservoir-induced landslides since the filling of the Three Gorges reservoir in 2003. These landslides have been occurring in heavily fractured carbonate rock materials along the rim of the reservoir in the Wu Gorge. A detailed investigation was carried out to examine the influence of reservoir operations (filling and drawdown) on slope stabilities in the upper Wu Gorge. Field investigations reveal many collapses of various types occurred at the toe of the anaclinal rock slopes, owing to the long-term intensive river erosion caused by periodic fluctuation of the reservoir level. Analysis of data from deformation monitoring suggests that the temporal movement of the slopes shows seasonal fluctuations that correlate with reservoir levels and drawdown conditions, with induced slope acceleration peaking when reservoir levels are lowest. This may illustrate that the main mechanism is the reservoir drawdown, which induces an episodic seepage force in the highly permeable materials at the slope toes, and thus leads to the episodic rockslides. The coupled hydraulic-mechanical (HM) modeling of the G2 landslide, which occurred in 2008, shows that collapse initiated at the submerged slope toe, which then caused the upper slope to collapse in a rock topple-rock slide pattern. The results imply that preventing water erosion at the slope toe might be an effective way for landslide prevention in the study area.
NASA Astrophysics Data System (ADS)
Walker, C. C.; Gardner, A. S.
2016-12-01
Over the past 50 years, several Antarctic Peninsula ice shelves have retreated or collapsed completely. One such collapse was the Wordie Ice Shelf (WIS), located in Marguerite Bay, which began to disintegrate around 1989. We use several observational datasets to show that the glaciers that used to maintain WIS have experienced a surprising acceleration in flow ( 500m/yr) that began 2008, nearly 20 years after the onset of WIS collapse. During the same period, airborne altimetry from NASA Operation IceBridge shows the glaciers experienced a drawdown at their calving fronts between 4 and 9 m/yr, a near-doubling in rate of elevation change from the 1990's and early-2000's. The time lag between WIS collapse and rapid glacier drawdown suggests that these recent changes are unrelated to loss of buttressing. We identify possible links to changes in ocean conditions using in-situ Palmer Station Long-Term Ecological Research (PAL LTER) ocean CTD-gridded observations (Martinson et al., 2008) taken along the continental shelf on the west Antarctic Peninsula (WAP) since 1993. We use ECCO2 simulations and atmospheric reanalysis data to characterize changes in atmospheric forcing. We also measure changes in ice shelf area using historic archives and Landsat imagery for 50 glacier systems along the WAP from 1945 to present. Surface structural changes in the WIS system, e.g., melt ponds, sea/fast ice presence, and crevasse density/orientation, are also examined. We conclude that recent changes in WIS tributaries likely resulted from a significant increase in upwelling of warm, salty Upper Circumpolar Deep Water (UCDW) due to enhanced wind forcing following coincident global atmospheric oscillation events, namely a positive Southern Annular Mode and a moderate La Nina event. This enabled enhanced incursions of UCDW into Marguerite Bay between 2008-2014, in part due to the deep Marguerite Trough that connects the bay to the continental shelf break, along which the southern boundary of the Antarctic Circumpolar Current flows.
Fitch, Taylor; Villanueva, Gabriela; Quadir, Mohammad M; Sagiraju, Hari K R; Alamgir, Hasanat
2015-07-01
Prevalence and risk factors of PTSD among injured garment workers who survived a major factory collapse. Survivors receiving treatment or rehabilitation care at one year post event were surveyed, which included Post Traumatic Stress Disorder Checklist Specific version. The respondents consisted of 181 people with a mean age of 27.8 years and a majority had less than high school education (91.2%). Multivariable logistic regression found that the odds of having PTSD was higher among married (OR: 3.2 [95% CI: 1.3-8.0]), those who used to work more than 70 hr/week (OR: 2.4 [1.1-5.3]), workers who used to hold higher job positions (OR: 2.6 [1.2-5.6]) or who had a concussion injury (OR: 3.7 [1.4-9.8]). Among the respondents, 83.4% remained unemployed, and only 57.3% (63 people) reported receiving a quarter or less of what they were promised as compensation. Probable PTSD was prevalent among surviving workers of the Rana Plaza building collapse in Bangladesh. © 2015 Wiley Periodicals, Inc.
NASA Technical Reports Server (NTRS)
Bleacher, Jacob; Michalski, Joseph
2012-01-01
Several irregularly shaped topographic depressions occur near the dichotomy boundary in northern Arabia Terra, Mars. The geomorphology of these features suggests that they formed by collapse, opposed to meteor impact. At least one depression (approx.55 by 85 km) displays geologic features indicating a complex, multi-stage collapse history. Features within and around the collapse structure indicate volcanic processes. The complex occurs within Hesperian ridged plains of likely volcanic origin and displays no crater rim or evidence for ejecta. Instead the depression consists of a series of circumferential graben and down-dropped blocks which also display upper surfaces similar to ridged plain lavas. Large blocks within the depression are tilted towards the crater center, and display graben that appear to have originally been linked with circumferential graben outside of the complex related to earlier collapse events. A nearly 700 m high mound exists along a graben within the complex that might be a vent. The deepest depression displays two sets of nearly continuous terraces, which we interpret as high-stands of a drained lava lake. These features appear similar to the black ledge described during the Kilauea Iki eruption in 1959. A lacustrine origin for the terraces seems unlikely because of the paucity of channels found in or around the depression that could be linked to aqueous surface processes. In addition, there is no obvious evidence for lacustrine sediments within the basin. Together with the presence of significant faulting that is indicative of collapse we conclude that this crater complex represents a large caldera formed in the Late Noachian to Early Hesperian. Other linear and irregular depressions in the region also might be linked to ancient volcanism. If that hypothesis is correct, it suggests that northern Arabia Terra could contain a large, previously unrecognized highland igneous province. Evacuation of magma via explosive and effusive activity produced localized collapse, might have contributed to nearby ridged plains, and pyroclastic materials erupted from these vents might have supplied sediments in fretted terrain and other deposits. The recognition of volcanoes within Arabia Terra expands the known extent of Noachian-Hesperian volcanism to cover much of the preserved martian highland crust.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rubin, Allison; Cooper, Kari M.; Leever, Marissa
Large silicic volcanic centers produce both small rhyolitic eruptions and catastrophic caldera-forming eruptions. Although changes in trace element and isotopic compositions within eruptions following caldera collapse have been observed at rhyolitic volcanic centers such as Yellowstone and Long Valley, much still remains unknown about the ways in which magma reservoirs are affected by caldera collapse. We present 238U– 230Th age, trace element, and Hf isotopic data from individual zircon crystals from four eruptions from the Okataina Volcanic Center, Taupo Volcanic Zone, New Zealand, in order to assess changes in trace element and isotopic composition of the reservoir following the 45-kamore » caldera-forming Rotoiti eruption. Our data indicate that (1) mixing of magmas derived from crustal melts and mantle melts takes place within the shallow reservoir; (2) while the basic processes of melt generation likely did not change significantly between pre- and post-caldera rhyolites, post-caldera zircons show increased trace element and isotopic heterogeneity that suggests a decrease in the degree of interconnectedness of the liquid within the reservoir following collapse; and (3) post-caldera eruptions from different vents indicate different storage times of the amalgamated melt prior to eruption. Furthermore, these data further suggest that the timescales needed to generate large volumes of eruptible melt may depend on the timescales needed to increase interconnectedness and achieve widespread homogenization throughout the reservoir.« less
Rubin, Allison; Cooper, Kari M.; Leever, Marissa; ...
2015-12-15
Large silicic volcanic centers produce both small rhyolitic eruptions and catastrophic caldera-forming eruptions. Although changes in trace element and isotopic compositions within eruptions following caldera collapse have been observed at rhyolitic volcanic centers such as Yellowstone and Long Valley, much still remains unknown about the ways in which magma reservoirs are affected by caldera collapse. We present 238U– 230Th age, trace element, and Hf isotopic data from individual zircon crystals from four eruptions from the Okataina Volcanic Center, Taupo Volcanic Zone, New Zealand, in order to assess changes in trace element and isotopic composition of the reservoir following the 45-kamore » caldera-forming Rotoiti eruption. Our data indicate that (1) mixing of magmas derived from crustal melts and mantle melts takes place within the shallow reservoir; (2) while the basic processes of melt generation likely did not change significantly between pre- and post-caldera rhyolites, post-caldera zircons show increased trace element and isotopic heterogeneity that suggests a decrease in the degree of interconnectedness of the liquid within the reservoir following collapse; and (3) post-caldera eruptions from different vents indicate different storage times of the amalgamated melt prior to eruption. Furthermore, these data further suggest that the timescales needed to generate large volumes of eruptible melt may depend on the timescales needed to increase interconnectedness and achieve widespread homogenization throughout the reservoir.« less
MRI Evaluation of Post Core Decompression Changes in Avascular Necrosis of Hip.
Nori, Madhavi; Marupaka, Sravan Kumar; Alluri, Swathi; Md, Naseeruddin; Irfan, Kazi Amir; Jampala, Venkateshwarlu; Apsingi, Sunil; Eachempati, Krishna Kiran
2015-12-01
Avascular necrosis of hip typically presents in young patients. Core decompression in precollapse stage provides pain relief and preservation of femoral head. The results of core decompression vary considerably despite early diagnosis. The role of MRI in monitoring patients post surgically has not been clearly defined. To study pre and post core decompression MRI changes in avascular necrosis of hip. This is a contiguous observational cohort of 40 hips treated by core decompression for precollapse avascular necrosis of femoral head, who had a baseline MRI performed before surgery. Core decompression of the femoral head was performed within 4 weeks. Follow up radiograph and MRI scans were done at six months. Harris hip score preoperatively, 1 month and 6 months after the surgery was noted. Success in this study was defined as postoperative increase in Harris hip score (HHS) by 20 points and no additional femoral collapse. End point of clinical adverse outcome as defined by fall in Harris hip score was conversion or intention to convert to total hip replacement (THR). MRI parameters in the follow up scan were compared to the preoperative MRI. Effect of core decompression on bone marrow oedema and femoral head collapse was noted. Results were analysed using SPSS software version. Harris hip score improved from 57 to 80 in all patients initially. Six hips had a fall in Harris hip score to mean value of 34.1 during follow up (9 to 12 months) and underwent total hip replacement. MRI predictors of positive outcome are lesions with grade A extent, Grade A & B location. Bone marrow oedema with lesions less than 50% involvement, medial and central location. Careful selection of patients by MR criteria for core decompression provides satisfactory outcome in precollapse stage of avascular necrosis of hip.
Study of the upper airway of obstructive sleep apnea patient using fluid structure interaction.
Liu, Yang; Mitchell, Jennifer; Chen, Yitung; Yim, Woosoon; Chu, Wenxiao; Wang, Robert C
2018-02-01
Up to 14% of the U.S. population is estimated to have obstructive sleep apnea (OSA), while the outcomes of the treatments have variable results. In the current study, a three-dimensional fluid-structure interaction modeling was applied to simulate the upper airway to identify the precise location, severity, and characteristic of airway collapse. This was accomplished using Simpleware ® and ANSYS ® software applied to a 3-D rendering of the airway in a real patient with severe OSA. During this simulation, areas which are prone to collapse and precipitate apneic episodes were identified at the tip of the soft palate and the base of the tongue, with intrathoracic pressure as low as -1370 Pa. These results are consistent with anatomical structures currently indicated and targeted in the treatment of OSA. This improved FSI modeling simulation, which is the first to completely model the whole upper airway without consideration of the nasal cavity in OSA, and can allow virtual modification of the airway prior to actual treatment by doctors. Copyright © 2018 Elsevier B.V. All rights reserved.
RESPIRATORY MODULATION OF LINGUAL MUSCLE ACTIVITY ACROSS SLEEP-WAKE STATES IN RATS
Stettner, Georg M.; Rukhadze, Irma; Mann, Graziella L.; Lei, Yanlin; Kubin, Leszek
2013-01-01
In obstructive sleep apnea (OSA) patients, inspiratory activation (IA) of lingual muscles protects the upper airway from collapse. We aimed to determine when rats’ lingual muscles exhibit IA. In 5 Sprague-Dawley and 3 Wistar rats, we monitored cortical EEG and lingual, diaphragmatic and nuchal electromyograms (EMGs), and identified segments of records when lingual EMG exhibited IA. Individual segments lasted 2.4–269 s (median: 14.5 s), most (89%) occurred during slow-wave sleep (SWS), and they collectively occupied 0.3–6.1% of the total recording time. IA usually started to increase with a delay after SWS onset and ended with an arousal, or declined prior to rapid eye movement sleep. IA of lingual EMG was not accompanied by increased diaphragmatic activity or respiratory rate changes, but occurred when cortical EEG power was particularly low in a low beta-1 frequency range (12.5–16.4 Hz). A deep SWS-related activation of upper airway muscles may be an endogenous phenomenon designed to protect the upper airway against collapse. PMID:23732510
European Neolithic societies showed early warning signals of population collapse.
Downey, Sean S; Haas, W Randall; Shennan, Stephen J
2016-08-30
Ecosystems on the verge of major reorganization-regime shift-may exhibit declining resilience, which can be detected using a collection of generic statistical tests known as early warning signals (EWSs). This study explores whether EWSs anticipated human population collapse during the European Neolithic. It analyzes recent reconstructions of European Neolithic (8-4 kya) population trends that reveal regime shifts from a period of rapid growth following the introduction of agriculture to a period of instability and collapse. We find statistical support for EWSs in advance of population collapse. Seven of nine regional datasets exhibit increasing autocorrelation and variance leading up to collapse, suggesting that these societies began to recover from perturbation more slowly as resilience declined. We derive EWS statistics from a prehistoric population proxy based on summed archaeological radiocarbon date probability densities. We use simulation to validate our methods and show that sampling biases, atmospheric effects, radiocarbon calibration error, and taphonomic processes are unlikely to explain the observed EWS patterns. The implications of these results for understanding the dynamics of Neolithic ecosystems are discussed, and we present a general framework for analyzing societal regime shifts using EWS at large spatial and temporal scales. We suggest that our findings are consistent with an adaptive cycling model that highlights both the vulnerability and resilience of early European populations. We close by discussing the implications of the detection of EWS in human systems for archaeology and sustainability science.
Prediction of the wetting-induced collapse behaviour using the soil-water characteristic curve
NASA Astrophysics Data System (ADS)
Xie, Wan-Li; Li, Ping; Vanapalli, Sai K.; Wang, Jia-Ding
2018-01-01
Collapsible soils go through three distinct phases in response to matric suction decrease during wetting: pre-collapse phase, collapse phase and post-collapse phase. It is reasonable and conservative to consider a strain path that includes a pre-collapse phase in which constant volume is maintained and a collapse phase that extends to the final matric suction to be experienced by collapsible soils during wetting. Upon this assumption, a method is proposed for predicting the collapse behaviour due to wetting. To use the proposed method, two parameters, critical suction and collapse rate, are required. The former is the suction value below which significant collapse deformations take place in response to matric suction decease, and the later is the rate at which void ratio reduces with matric suction in the collapse phase. The value of critical suction can be estimated from the water-entry value taking account of both the microstructure characteristics and collapse mechanism of fine-grained collapsible soils; the wetting soil-water characteristic curve thus can be used as a tool. Five sets of data of wetting tests on both compacted and natural collapsible soils reported in the literature were used to validate the proposed method. The critical suction values were estimated from the water-entry value with parameter a that is suggested to vary between 0.10 and 0.25 for compacted soils and to be lower for natural collapsible soils. The results of a field permeation test in collapsible loess soils were also used to validate the proposed method. The relatively good agreement between the measured and estimated collapse deformations suggests that the proposed method can provide reasonable prediction of the collapse behaviour due to wetting.
Nelson, C. Hans; Bacon, Charles R.; Robinson, Stephen W.; Adam, David P.; Bradbury, J. Platt; Barber, John H.; Schwartz, Deborah; Vagenas, Ginger
1994-01-01
Apparent phreatic explosion craters, caldera-floor volcanic cones, and geothermal features outline a ring fracture zone along which Mount Mazama collapsed to form the Crater Lake caldera during its climactic eruption about 6,850 yr B.P. Within a few years, subaerial deposits infilled the phreatic craters and then formed a thick wedge (10-20 m) of mass flow deposits shed from caldera walls. Intense volcanic activity (phreatic explosions, subaerial flows, and hydrothermal venting) occurred during this early postcaldera stage, and a central platform of subaerial andesite flows and scoria formed on the caldera floor.Radiocarbon ages suggest that deposition of Iacustrine hemipelagic sediment began on the central platform about 150 yr after the caldera collapse. This is the minimum time to fill the lake halfway with water and cover the platform assuming present hydrologic conditions of precipitation and evaporation but with negligible leakage of lake water. Wizard Island formed during the final part of the 300-yr lake-filling period as shown by its (1) upper subaerial lava flows from 0 to -70 m below present water level and lower subaqueous lava flows from -70 to -500 m and by (2) lacustrine turbidite sand derived from Wizard Island that was deposited on the central platform about 350 yr after the caldera collapse. Pollen stratigraphy indicates that the warm and dry climate of middle Holocene time correlates with the early lake deposits. Diatom stratigraphy also suggests a more thermally stratified and phosphate-rich environment associated respectively with this climate and greater hydrothermal activity during the early lake history.Apparent coarse-grained and thick-bedded turbidites of the early lake beds were deposited throughout northwest, southwest, and eastern basins during the time that volcanic and seismic activity formed the subaqueous Wizard Island, Merriam Cone, and rhyodacite dome. The last known postcaldera volcanic activity produced a subaqueous rhyodacite ash bed and dome about 4,240 yr B.P. The late lake beds with base-of-slope aprons and thin, fine-grained basin-plain turbidites were deposited during the volcanically quiescent period of the past 4,000 yr.Deposits in Crater Lake and on similar caldera floors suggest that four stages characterize the postcaldera evolution of smaller (≤10 km in diameter) terrestrial caldera lake floors: (1) initial-stage caldera collapse forms the ring fracture zone that controls location of the main volcanic eruptive centers and sedimentary basin depocenters on the caldera floor; (2) early-stage subaerial sedimentation rapidly fills ring-fracture depressions and constructs basin-floor debris fans from calderawall landslides; (3) first-stage subaqueous sedimentation deposits thick flat-lying lake turbidites throughout basins, while a thin blanket of hemipelagic sediment covers volcanic edifices that continue to form concurrently with lake sedimentation; and (4) second-stage subaqueous sedimentation after the waning of major volcanic activity and the earlier periods of most rapid sedimentation develops small sili-ciclastic basin base-of-slope turbidite aprons and central basin plains. Renewed volcanic activity or lake destruction could cause part or all of the cycle to repeat.
Anatomic optical coherence tomography for dynamic imaging of the upper airway
NASA Astrophysics Data System (ADS)
Bu, Ruofei; Balakrishnan, Santosh; Iftimia, Nicusor; Price, Hillel; Zdanski, Carlton; Oldenburg, Amy L.
2017-03-01
To aid in diagnosis and treatment of upper airway obstructive disorders (UAOD), we propose anatomic Optical Coherence Tomography (aOCT) for endoscopic imaging of the upper airway lumen with high speed and resolution. aOCT and CT scans are performed sequentially on in vivo swine to compare dynamic airway imaging data. The aOCT system is capable of capturing the dynamic deformation of the airway during respiration. This may lead to methods for airway elastography and aid in our understanding of dynamic collapse in UAOD.
Yegïn, Yakup; Çelik, Mustafa; Kaya, Kamïl Hakan; Koç, Arzu Karaman; Kayhan, Fatma Tülin
Knowledge of the site of obstruction and the pattern of airway collapse is essential for determining correct surgical and medical management of patients with Obstructive Sleep Apnea Syndrome (OSAS). To this end, several diagnostic tests and procedures have been developed. To determine whether drug-induced sleep endoscopy (DISE) or Müller's maneuver (MM) would be more successful at identifying the site of obstruction and the pattern of upper airway collapse in patients with OSAS. The study included 63 patients (52 male and 11 female) who were diagnosed with OSAS at our clinic. Ages ranged from 30 to 66 years old and the average age was 48.5 years. All patients underwent DISE and MM and the results of these examinations were characterized according to the region/degree of obstruction as well as the VOTE classification. The results of each test were analyzed per upper airway level and compared using statistical analysis (Cohen's kappa statistic test). There was statistically significant concordance between the results from DISE and MM for procedures involving the anteroposterior (73%), lateral (92.1%), and concentric (74.6%) configuration of the velum. Results from the lateral part of the oropharynx were also in concordance between the tests (58.7%). Results from the lateral configuration of the epiglottis were in concordance between the tests (87.3%). There was no statistically significant concordance between the two examinations for procedures involving the anteroposterior of the tongue (23.8%) and epiglottis (42.9%). We suggest that DISE has several advantages including safety, ease of use, and reliability, which outweigh MM in terms of the ability to diagnose sites of obstruction and the pattern of upper airway collapse. Also, MM can provide some knowledge of the pattern of pharyngeal collapse. Furthermore, we also recommend using the VOTE classification in combination with DISE. Copyright © 2016 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.
Reconnaissance geologic map of the Dixonville 7.5' quadrangle, Oregon
Jayko, Angela S.; Wells, Ray E.; Digital Database by Givler, R. W.; Fenton, J.S.; Sinor, M.
2001-01-01
The Dixonville 7.5 minute quadrangle is situated near the edge of two major geologic and tectonic provinces the northernmost Klamath Mountains and the southeastern part of the Oregon Coast Ranges (Figure 1). Rocks of the Klamath Mountains province that lie within the study area include ultramafic, mafic, intermediate and siliceous igneous types (Diller, 1898, Ramp, 1972, Ryberg, 1984). Similar rock associations that lie to the southwest yield Late Jurassic and earliest Cretaceous radiometric ages (Dott, 1965, Saleeby, et al., 1982, Hotz, 1971, Harper and Wright, 1984). These rocks, which are part of the Western Klamath terrane (Western Jurassic belt of (Irwin, 1964), are considered to have formed within an extensive volcanic arc and rifted arc complex (Harper and Wright, 1984) that lay along western North America during the Late Jurassic (Garcia, 1979, Garcia, 1982, Saleeby, et al., 1982, Ryberg, 1984). Imbricate thrust faulting and collapse of the arc during the Nevadan orogeny, which ranged in age between about 150 to 145 Ma in the Klamath region (Coleman, 1972, Saleeby, et al., 1982, Harper and Wright, 1984) was syntectonic with, or closely followed by deposition of the volcano-lithic clastic rocks of the Myrtle Group. The Myrtle Group consists of Upper Jurassic and Lower to middle Cretaceous turbidity and mass flow deposits considered to be either arc basin and/or post-orogenic flysh basins that were syntectonic with the waning phases of arc collapse (Imlay et al., 1959, Ryberg, 1984, Garcia, 1982, Roure.and Blanchet, 1983). The intermediate and mafic igneous rocks of the Rogue arc and the pre-Nevadan sedimentary cover (the Galice Formation, (Garcia, 1979) are intruded by siliceous and intermediate plutonic rocks principally of quartz diorite and granodiorite composition (Dott, 1965, Saleeby, et al., 1982, Garcia, 1982, Harper and Wright, 1984). The plutonic rocks are locally tectonized into amphibolite, gneiss, banded gneiss and augen gneiss. Similar metamorphic rocks have yielded metamorphic ages of 165 to 150 Ma (Coleman, 1972, Hotz, 1971, Saleeby, et al., 1982, Coleman and Lanphere, 1991). The Jurassic arc rocks and sedimentary cover occur as a tectonic outlier in this region (Figure 2) as they are bound to the northwest and southeast by melange, broken formation and semi-schists of the Dothan Formation and Dothan Formation(?) that are considered part of a late Mesozoic accretion complex (Ramp, 1972, Blake, et al., 1985). The plutonism that accompanied arc formation and tectonic collapse of the arc does not intrude the structurally underlying Dothan Formation, indicating major fault displacements since the Early Cretaceous. Semischistose and schistose rocks of the accretion complex have yielded metamorphic ages of around 125-140 Ma where they have been studied to the southwest (Coleman and Lanphere, 1971, Dott, 1965, Coleman, 1972). These rocks were unroofed and unconformably overlain by marine deposits by late early Eocene time (Baldwin, 1974). The early Tertiary history of this region is controversial. The most recent interpretation is that during the Paleocene and early Eocene the convergent margin was undergoing transtension or forearc extension as suggested by the voluminous extrusion of pillow basalt and related dike complexes (Wells, et al., 1984, Snavely, 1987). This episode was followed shortly by thrust and strike-slip faulting in the late early Eocene (Ryberg, 1984). During the Eocene, the Mesozoic convergent margin association of arc, clastic basin, and accretion complex was partly unroofed and faulted against early Cenozoic rocks of the Oregon Coast Ranges (Ramp, 1972, Baldwin, 1974, Champ, 1969, Ryberg, 1984). Faults that are typical of this period of deformation include high-angle reverse faults with a very strong component of strike-slip displacement characterized by a low-angle rake of striae. Thrust and oblique-slip faults are ubiquitous in early Tertiary rocks to the northwest (Ryberg, 1984, Niem and Niem, 1990). The late Mesozoic and early Cenozoic arc and forearc rocks are unconformably overlain to the east by the late Eocene and younger, mainly continental fluvial deposits and pyroclastic flows of the Cascade arc (Peck, et al., 1964, Baldwin, 1974, Walker and MacLeod, 1991). Minor fossiliferous shallow marine sandstone is locally present. The volcanic sequence consists of a homoclinal section of about 1 to 2 kilometers of andesitic to rhyolitic flows and ash flow tuff. The section is gently east-tilted and is slightly disrupted by NE trending faults with apparent normal separation.
Pilge, Hakan; Bittersohl, Bernd; Schneppendahl, Johannes; Hesper, Tobias; Zilkens, Christoph; Ruppert, Martin; Krauspe, Rüdiger; Jäger, Marcus
2016-11-17
With disease progression, avascular necrosis (AVN) of the femoral head may lead to a collapse of the articular surface. The exact pathophysiology of AVN remains unclear, although several conditions are known that can result in spontaneous cell death, leading to a reduction of trabecular bone and the development of AVN. Hip AVN treatment is stage-dependent in which two main stages of the disease can be distinguished: pre-collapse (ARCO 0-II) and post-collapse stage (ARCO III-IV, crescent sign). In the pre-collapse phase, core decompression (CD), with or without the addition of bone marrow ( e.g . bone marrow aspirate concentrate, BMAC) or bone graft, is a common treatment alternative. In the post-collapse phase, THA (total hip arthroplasty) must be performed in most of the patients. In addition to surgical treatment, the intravenous application of Iloprost has been shown to have a curative potential and analgesic effect. From October 2009 to October 2014, 49 patients with AVN (stages I-III) were treated with core decompression at our institution. All patients were divided into group A (CD + BMAC) and group B (CD alone). Of these patients, 20 were included in a matched pair analysis. The patients were matched to age, gender, ARCO-stage, Kerboul combined necrotic angle, the cause of AVN, and whether Iloprost-therapy was performed. The Merle d'Aubigné Score and the Kerboul combined necrotic angle in a-p and lateral radiographs were evaluated pre- and postoperatively. The primary endpoint was a total hip arthroplasty. In group A, two patients needed THA while in group B four patients were treated with THA. In group A, the Merle d'Aubigné Score improved from 13.5 (pre-operatively) to 15.3 (postoperatively). In group B there was no difference between the pre- (14.3) and postoperative (14.1) assessment. The mean of the Kerboul angle showed no difference in both groups compared pre- to postoperatively (group A: pre-op 212°, postop 220°, group B: pre-op 213, postop 222°). Regarding radiographic evaluation, the interobserver variability revealed a moderate agreement between two raters regarding the pre-(ICC 0.594) and postoperative analysis (ICC 0.604).This study demonstrates that CD in combination with the application of autologous bone marrow aspirate concentrate into the femoral head seems to be a safe and efficient treatment alternative in the early stages of AVN of the femoral head when compared to CD alone.
Kirkham, R.M.; Streufert, R.K.; Budahn, J.R.; Kunk, Michael J.; Perry, W.J.
2001-01-01
Dissolution and flow of Pennsylvanian evaporitic rocks in west-central Colorado created the Carbondale Collapse Center, a 450 mi2 structural depression with about 4,000 ft of vertical collapse during the late Cenozoic. This paper describes evidence of collapse in the lower Roaring Fork River valley. Both the lateral extent and amount of vertical collapse is constrained by deformed upper Cenozoic volcanic rocks that have been correlated using field mapping, 40Ar/39Ar geochronology, geochemistry, and paleomagnetism. The Carbondale Collapse Center is one of at least two contiguous areas that have experienced major evaporite tectonism during the late Cenozoic. Historic sinkholes, deformed Holocene deposits, and modern high-salinity loads in the rivers and thermal springs indicate the collapse process continues today. Flow of evaporitic rocks is an important element in the collapse process, and during initial stages of collapse it was probably the primary causative mechanism. Dissolution, however, is the ultimate means by which evaporite is removed from the collapse area. As the Roaring Fork River began to rapidly down-cut through a broad volcanic plateau during the late Miocene, the underlying evaporite beds were subjected to differential overburden pressures. The evaporitic rocks flowed from beneath the upland areas where overburden pressures remained high, toward the Roaring Fork River Valley where the pressures were much lower. Along the valley the evaporitic rocks rose upward, sometimes as diapirs, forming or enhancing a valley anticline in bedrock and locally upwarping Pleistocene terraces. Wherever the evaporites encountered relatively fresh ground water, they were dissolved, forming underground voids into which overlying bedrock and surficial deposits subsided. The saline ground water eventually discharged to streams and rivers through thermal springs and by seepage into alluvial aquifers.
Distinct Element modeling of geophysical signatures during sinkhole collapse
NASA Astrophysics Data System (ADS)
Al-Halbouni, Djamil; Holohan, Eoghan P.; Taheri, Abbas; Dahm, Torsten
2017-04-01
A sinkhole forms due to the collapse of rocks or soil near the Earth's surface into an underground cavity. Such cavities represent large secondary pore spaces derived by dissolution and subrosion in the underground. By changing the stress field in the surrounding material, the growth of cavities can lead to a positive feedback, in which expansion and mechanical instability in the surrounding material increases or generates new secondary pore space (e.g. by fracturing), which in turn increases the cavity size, etc. A sinkhole forms due to the eventual subsidence or collapse of the overburden that becomes destabilized and fails all the way to the Earth's surface. Both natural processes like (sub)surface water movement and earthquakes, and human activities, such as mining, construction and groundwater extraction, intensify such feedbacks. The development of models for the mechanical interaction of a growing cavity and fracturing of its surrounding material, thus capturing related precursory geophysical signatures, has been limited, however. Here we report on the advances of a general, simplified approach to simulating cavity growth and sinkhole formation by using 2D Distinct Element Modeling (DEM) PFC5.0 software and thereby constraining pre-, syn- and post-collapse geophysical and geodetic signatures. This physically realistic approach allows for spontaneous cavity development and dislocation of rock mass to be simulated by bonded particle formulation of DEM. First, we present calibration and validation of our model. Surface subsidence above an instantaneously excavated circular cavity is tracked and compared with an incrementally increasing dissolution zone both for purely elastic and non-elastic material.This validation is important for the optimal choice of model dimensions and particles size with respect to simulation time. Second, a cavity growth approach is presented and compared to a well-documented case study, the deliberately intensified sinkhole collapse at Cerville-Buissoncourt in France. The outcomes of our model are compared with available extensiometer, surface-subsidence and microseismicity measurements during the pre- and syn-collapse period. The proposed model development and a possible archive of modeled scenarios may, in combination with a geodetic and seismological sinkhole monitoring, contribute to an early-warning tool for end-users and decision makers in areas affected by natural (e.g. Dead Sea) or man-made sinkhole collapses (mines).
NASA Technical Reports Server (NTRS)
2003-01-01
MGS MOC Release No. MOC2-549, 19 November 2003
The volcanic plains to the east, southeast, and south of the giant Tharsis volcano, Pavonis Mons, are dotted by dozens of small volcanoes. This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows an example located near 2.1oS, 109.1oW. The elongate depression in the lower left (southwest) quarter of the image is the collapsed vent area for this small, unnamed volcano. A slightly sinuous, leveed channel runs from the depression toward the upper right (north-northeast); this is the trace of a collapsed lava tube. The entire scene has been mantled by dust, such that none of the original volcanic rocks are exposed--except minor occurrences on the steepest slopes in the vent area. The scene is 3 km (1.9 mi) wide and illuminated by sunlight from the left/upper left.Loculated pneumothorax due to a rare combination resulting in an interesting chest radiograph.
Isaac, Barney Thomas Jesudason; Samuel, Johnson Thamarathu; Mukherjee, Dipak K; Pittman, Marcus
2017-11-01
A 35 years old man presented with acute onset left sided pleuritic chest pain and shortness of breath. On evaluation, he was found to have an interesting chest radiograph which showed a loculated pneumothorax with collapse of the left upper lobe and lingula but fully expanded left lower lobe. He is a known asthmatic who had allergic broncho pulmonary aspergillosis (ABPA) previously with left upper lobe and lingular collapse secondary to mucous plugging. This resolved on treatment with steroids and itraconazole. An interesting combination of events is proposed to explain the current presentation. CT scan chest and blood tests confirmed this sequence of events. He was appropriately treated resulting in complete clinical and radiological recovery. The events leading to the presentation and the likely physiological background for this interesting chest radiograph are discussed. © 2016 John Wiley & Sons Ltd.
Zilhão, João
2018-01-01
We use stone tool refitting to assess palimpsest formation and stratigraphic integrity in the basal units of the Gruta da Oliveira archeo-stratigraphic sequence, layers 15–27, which TL and U-series dating places in late Marine Isotope Stage (MIS) 5 or early MIS 4. As in most karst contexts, the formation of this succession involved multiple and complex phenomena, including subsidence, bioturbation, carnivore activity and runoff as agents of potential post-depositional disturbance. During phases of stabilization, such as represented by layers 15, 21 and 22, the excavated area was inhabited and refits corroborate that post-depositional displacement is negligible. Layers 23–25 and 16–19 correspond to subdivisions that slice thick geological units primarily formed of material derived from the cave’s entrance via slope dynamics. Refit links are consistent with rapid fill-up of the interstitial spaces found in the Karren-like bedrock (for layers 23–25), or left between large boulders after major roof-collapse events (for layers 16–19). Layers 26 (the “Mousterian Cone”) and 27 are a “bottom-of-hourglass” deposit underlying the main sedimentary body; the refits show that this deposit consists of material derived from layers 15–25 that gravitated through fissures open in the sedimentary column above. Layer 20, at the interface between two major stratigraphic ensembles, requires additional analysis. Throughout, we found significant vertical dispersion along the contact between sedimentary fill and cave wall. Given these findings, a preliminary analysis of technological change across the studied sequence organized the lithic assemblages into five ensembles: layer 15; layers 16–19; layer 20; layers 21–22; layers 23–25. The lower ensembles show higher percentages of flint and of the Levallois method. Uniquely at the site, the two upper ensembles feature bifaces and cleavers. PMID:29451892
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sawant, A; Modiri, A; Bland, R
Purpose: Post-treatment radiation injury to central and peripheral airways is a potentially important, yet under-investigated determinant of toxicity in lung stereotactic ablative radiotherapy (SAbR). We integrate virtual bronchoscopy technology into the radiotherapy planning process to spatially map and quantify the radiosensitivity of bronchial segments, and propose novel IMRT planning that limits airway dose through non-isotropic intermediate- and low-dose spillage. Methods: Pre- and ∼8.5 months post-SAbR diagnostic-quality CT scans were retrospectively collected from six NSCLC patients (50–60Gy in 3–5 fractions). From each scan, ∼5 branching levels of the bronchial tree were segmented using LungPoint, a virtual bronchoscopic navigation system. The pre-SAbRmore » CT and the segmented bronchial tree were imported into the Eclipse treatment planning system and deformably registered to the planning CT. The five-fraction equivalent dose from the clinically-delivered plan was calculated for each segment using the Universal Survival Curve model. The pre- and post-SAbR CTs were used to evaluate radiation-induced segmental collapse. Two of six patients exhibited significant segmental collapse with associated atelectasis and fibrosis, and were re-planned using IMRT. Results: Multivariate stepwise logistic regression over six patients (81 segments) showed that D0.01cc (minimum point dose within the 0.01cc receiving highest dose) was a significant independent factor associated with collapse (odds-ratio=1.17, p=0.010). The D0.01cc threshold for collapse was 57Gy, above which, collapse rate was 45%. In the two patients exhibiting segmental collapse, 22 out of 32 segments showed D0.01cc >57Gy. IMRT re-planning reduced D0.01cc below 57Gy in 15 of the 22 segments (68%) while simultaneously achieving the original clinical plan objectives for PTV coverage and OAR-sparing. Conclusion: Our results indicate that the administration of lung SAbR can Result in significant injury to bronchial segments, potentially impairing post-SAbR lung function. To our knowledge, this is the first investigation of functional avoidance based on mapping and minimizing dose to individual bronchial segments. The presenting author receives research funding from Varian Medical Systems, Elekta, and VisionRT.« less
Gupta, Rishein; Wali, Shradha; Yu, Jieh-Juen; Chambers, James P; Zhong, Guangming; Murthy, Ashlesh K; Bakar, Sazaly Abu; Guentzel, M N; Arulanandam, Bernard P
2014-10-01
The leading cause of sexually transmitted bacterial infection is Chlamydia trachomatis. The aim of this study is to investigate the early events in colonization of this bacterium within the murine genital tract. An in vivo animal body imaging technology was used to track fluorophore labeled C. muridarum elementary bodies (EBs) inoculated intravaginally in C57BL/6 mice during the first 24 h of infection. Ascension of viable EBs was observed (1) to be localized to the lower regions of the murine genital tract within the first 24 h post challenge and (2) was dose independent during this early exposure period. Molecular detection revealed enhanced bacterial load in lower regions of the genital tract with increasing bacterial load in the upper region beginning 12 h post inoculation. This study provides additional insight into chlamydial colonization in the murine genital tract during the first 12-24 h following inoculation.
Atmospheric Collapse on Early Mars: The Role of CO2 Clouds
NASA Technical Reports Server (NTRS)
Kahre, M. A.; Haberle, R. M.; Steakley, K. E.; Murphy, J. R.; Kling, A.
2017-01-01
The abundance of evidence that liquid water flowed on the surface early in Mars' history strongly implies that the early Martian atmosphere was significantly more massive than it is today. While it seems clear that the total CO2 inventory was likely substantially larger in the past, the fundamental question about the physical state of that CO2 is not completely understood. Because the temperature at which CO2 condenses increases with surface pressure, surface CO2 ice is more likely to form and persist as the atmospheric mass increases. For the atmosphere to remain stable against collapse, there must be enough energy, distributed planet wide, to stave off the formation of permanent CO2 caps that leads to atmospheric collapse. The presence of a "faint young sun" that was likely about 25 percent less luminous 3.8 billion years ago than the sun today makes this even more difficult. Several physical processes play a role in the ultimate stability of a CO2 atmosphere. The system is regulated by the energy balance between solar insolation, the radiative effects of the atmosphere and its constituents, atmospheric heat transport, heat exchange between the surface and the atmosphere, and latent heating/cooling. Specific considerations in this balance for a given orbital obliquity/eccentricity and atmospheric mass are the albedo of the caps, the dust content of the atmosphere, and the presence of water and/or CO2 clouds. Forget et al. show that, for Mars' current obliquity (in a circular orbit), CO2 atmospheres ranging in surface pressure from 500 hectopascals to 3000 hectopascals would have been stable against collapsing into permanent surface ice reservoirs. Soto et al. examined a similar range in initial surface pressure to investigate atmospheric collapse and to compute collapse rates. CO2 clouds and their radiative effects were included in Forget et al. but they were not included in Soto et al. Here we focus on how CO2 clouds affect the stability of the atmosphere against collapse.
Black hole formation from the gravitational collapse of a nonspherical network of structures
NASA Astrophysics Data System (ADS)
Delgado Gaspar, Ismael; Hidalgo, Juan Carlos; Sussman, Roberto A.; Quiros, Israel
2018-05-01
We examine the gravitational collapse and black hole formation of multiple nonspherical configurations constructed from Szekeres dust models with positive spatial curvature that smoothly match to a Schwarzschild exterior. These configurations are made of an almost spherical central core region surrounded by a network of "pancake-like" overdensities and voids with spatial positions prescribed through standard initial conditions. We show that a full collapse into a focusing singularity, without shell crossings appearing before the formation of an apparent horizon, is not possible unless the full configuration becomes exactly or almost spherical. Seeking for black hole formation, we demand that shell crossings are covered by the apparent horizon. This requires very special fine-tuned initial conditions that impose very strong and unrealistic constraints on the total black hole mass and full collapse time. As a consequence, nonspherical nonrotating dust sources cannot furnish even minimally realistic toy models of black hole formation at astrophysical scales: demanding realistic collapse time scales yields huge unrealistic black hole masses, while simulations of typical astrophysical black hole masses collapse in unrealistically small times. We note, however, that the resulting time-mass constraint is compatible with early Universe models of primordial black hole formation, suitable in early dust-like environments. Finally, we argue that the shell crossings appearing when nonspherical dust structures collapse are an indicator that such structures do not form galactic mass black holes but virialize into stable stationary objects.
Genetics Home Reference: early infantile epileptic encephalopathy 1
... infantile epileptic encephalopathy 1 Early infantile epileptic encephalopathy 1 Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Early infantile epileptic encephalopathy 1 (EIEE1) is ...
Instability of the Antarctic Ross Sea Embayment as climate warms
NASA Astrophysics Data System (ADS)
Hughes, Terence; Zhao, Zihong; Hintz, Raymond; Fastook, James
2017-06-01
Collapse of the Antarctic Ice Sheet since the Last Glacial Maximum 18,000 years ago is most pronounced in the Ross Sea Embayment, which is partly ice-free during Antarctic summers, thereby breaching the O-ring of ice shelves and sea ice surrounding Antarctica that stabilizes the ice sheet. The O-ring may have vanished during Early Holocene (5000 to 3000 B.C.), Roman (1 to 400 A.D.), and Medieval (900 to 1300 A.D.) warm periods and reappeared during the Little Ice Age (1300 to 1900 A.D.). We postulate further collapse in the embayment during the post-1900 warming may be forestalled because East Antarctic outlet glaciers "nail" the Ross Ice Shelf to the Transantarctic Mountains so it can resist the push from West Antarctic ice streams. Our hypothesis is examined for Byrd Glacier and a static ice shelf using three modeling experiments having plastic, viscous, and viscoplastic solutions as more data and improved modeling became available. Observed crevasse patterns were not reproduced. A new research study is needed to model a dynamic Ross Ice Shelf with all its feeder ice streams, outlet glaciers, and ice calving dynamics in three dimensions over time to fully test our hypothesis. The required model must allow accelerated calving if further warming melts sea ice and discerps the ice shelf. Calving must then successively pull the outlet glacier "nails" so collapse of the marine West Antarctic Ice Sheet proceeds to completion.
SRTM Stereo Pair: Meseta de Somuncura, Patagonia, Argentina
2000-07-27
The Meseta de Somuncura is a semi-arid basalt plateau in northern Patagonia. This view of the northwestern part of the plateau, near Los Menucos, Argentina, shows numerous depressions where the upper basalt layers are missing or collapsed.
Evidence for slow late-glacial ice retreat in the upper Rangitata Valley, South Island, New Zealand
NASA Astrophysics Data System (ADS)
Shulmeister, J.; Fink, D.; Winkler, S.; Thackray, G. D.; Borsellino, R.; Hemmingsen, M.; Rittenour, T. M.
2018-04-01
A suite of cosmogenic radionuclide ages taken from boulders on lateral and latero-terminal moraines in the Rangitata Valley, eastern South Island, New Zealand demonstrates that relatively thick ice occupied valley reaches inland of the Rangitata Gorge until c. 21 ka. Thereafter ice began to thin, and by c. 17 ka it had retreated 33 km up-valley of the Rangitata Gorge to the Butler-Brabazon Downs, a structurally created basin in the upper Rangitata Valley. Despite its magnitude, this retreat represents a minor ice volume reduction from 21 ka to 17 ka, and numerous lateral moraines preserved suggest a relatively gradual retreat over that 4 ka period. In contrast to records from adjacent valleys, there is no evidence for an ice-collapse at c. 18 ka. We argue that the Rangitata record constitutes a more direct record of glacial response to deglacial climate than other records where glacial dynamics were influenced by proglacial lake development, such as the Rakaia Valley to the North and the major valleys in the Mackenzie Basin to the south-west. Our data supports the concept of a gradual warming during the early deglaciation in the South Island New Zealand.
European Neolithic societies showed early warning signals of population collapse
Downey, Sean S.; Haas, W. Randall; Shennan, Stephen J.
2016-01-01
Ecosystems on the verge of major reorganization—regime shift—may exhibit declining resilience, which can be detected using a collection of generic statistical tests known as early warning signals (EWSs). This study explores whether EWSs anticipated human population collapse during the European Neolithic. It analyzes recent reconstructions of European Neolithic (8–4 kya) population trends that reveal regime shifts from a period of rapid growth following the introduction of agriculture to a period of instability and collapse. We find statistical support for EWSs in advance of population collapse. Seven of nine regional datasets exhibit increasing autocorrelation and variance leading up to collapse, suggesting that these societies began to recover from perturbation more slowly as resilience declined. We derive EWS statistics from a prehistoric population proxy based on summed archaeological radiocarbon date probability densities. We use simulation to validate our methods and show that sampling biases, atmospheric effects, radiocarbon calibration error, and taphonomic processes are unlikely to explain the observed EWS patterns. The implications of these results for understanding the dynamics of Neolithic ecosystems are discussed, and we present a general framework for analyzing societal regime shifts using EWS at large spatial and temporal scales. We suggest that our findings are consistent with an adaptive cycling model that highlights both the vulnerability and resilience of early European populations. We close by discussing the implications of the detection of EWS in human systems for archaeology and sustainability science. PMID:27573833
Souza Possa, S; Braga Amador, C; Meira Costa, A; Takahama Sakamoto, E; Seiko Kondo, C; Maida Vasconcellos, A L; Moran de Brito, C M; Pereira Yamaguti, W
2014-01-01
The aim of this study was to evaluate the effectiveness of implementing a physical therapy guideline for patients undergoing upper abdominal surgery (UAS) in reducing the incidence of atelectasis and length of hospital stay in the postoperative period. A "before and after" study design with historical control was used. The "before" period included consecutive patients who underwent UAS before guideline implementation (intervention). The "after" period included consecutive patients after guideline implementation. Patients in the pre-intervention period were submitted to a program of physical therapy in which the treatment planning was based on the individual experience of each professional. On the other hand, patients who were included in the post-intervention period underwent a standardized program of physical therapy with a focus on the use of additional strategies (EPAP, incentive spirometry and early mobilization). There was a significant increase in the use of incentive spirometry and positive expiratory airway pressure after guideline implementation. Moreover, it was observed that early ambulation occurred in all patients in the post-intervention period. No patient who adhered totally to the guideline in the post-intervention period developed atelectasis. Individuals in the post-intervention period presented a shorter length of hospital stay (9.2±4.1 days) compared to patients in the pre-intervention period (12.1±8.3 days) (p<0.05). The implementation of a physical therapy guideline for patients undergoing UAS resulted in reduced incidence of atelectasis and reduction in length of hospital stay in the postoperative period. Copyright © 2013 Sociedade Portuguesa de Pneumologia. Published by Elsevier España. All rights reserved.
Fletcher-Smith, Joanna C; Walker, Dawn-Marie; Sprigg, Nikola; James, Marilyn; Walker, Marion F; Allatt, Kate; Mehta, Rajnikant; Pandyan, Anand D
2016-01-01
Introduction Approximately 70% of patients with stroke experience impaired arm function, which is persistent and disabling for an estimated 40%. Loss of function reduces independence in daily activities and impacts on quality of life. Muscles in those who do not recover functional movement in the stroke affected arm are at risk of atrophy and contractures, which can be established as early as 6 weeks following stroke. Pain is also common. This study aims to evaluate the feasibility of a randomised controlled trial to test the efficacy and cost-effectiveness of delivering early intensive electrical stimulation (ES) to prevent post-stroke complications in the paretic upper limb. Methods and analysis This is a feasibility randomised controlled trial (n=40) with embedded qualitative studies (patient/carer interviews and therapist focus groups) and feasibility economic evaluation. Patients will be recruited from the Stroke Unit at the Nottingham University Hospitals National Health Service (NHS) Trust within 72 h after stroke. Participants will be randomised to receive usual care or usual care and early ES to the wrist flexors and extensors for 30 min twice a day, 5 days a week for 3 months. The initial treatment(s) will be delivered by an occupational therapist or physiotherapist who will then train the patient and/or their nominated carer to self-manage subsequent treatments. Ethics and dissemination This study has been granted ethical approval by the National Research Ethics Service, East Midlands Nottingham1 Research Ethics Committee (ref: 15/EM/0006). To our knowledge, this is the first study of its kind of the early application (within 72 h post-stroke) of ES to both the wrist extensors and wrist flexors of stroke survivors with upper limb impairment. The results will inform the design of a definitive randomised controlled trial. Dissemination will include 2 peer-reviewed journal publications and presentations at national conferences. Trial registration number ISRCTN1648908; Pre-results. Clinicaltrials.gov ID: NCT02324634. PMID:26729394
NASA Astrophysics Data System (ADS)
Malekpour Alamdari, A.; Axen, G. J.; Hassanzadeh, J.
2014-12-01
Our knowledge about the spatial and temporal relationship between continental extension and its related magmatism is mainly from the western US where removal of a flat subducting slab from under the continent controlled thermal weakening and some extensional collapse. The Iranian plateau, where flat-slab subduction and its subsequent rollback is suggested for the Tertiary magmatic evolution, is an ideal place to see if a similar interaction exists. Between the Late Cretaceous and, at least, the Early Eocene, large-scale continental extension affected the NE Iranian plateau. An ~100 km-long, SE tilted upper to mid-crustal section was exhumed by slip along a low-angle, NW-dipping detachment fault. From SE to NW (young to old) this section includes late Cretaceous pelagic limestones of the Kashmar ophiolites, Late and Early Cretaceous sedimentary rocks, and the Late Triassic and older crystalline rocks of the Biarjmand-Shotor Kuh metamorphic core complex. Little pre-extensional magmatic activity exists in the tilted sequence and in surrounding regions, as Late Jurassic and Early Cretaceous dikes. Similarly, syn-extensional magmatism is absent. In contrast, the tilted sequence is unconformably overlain by >4000 m of volcanic rocks with age ranging from the Middle Eocene (explosive, calc-alkaline?) to the Late Eocene (effusive, alkaline). The absence of considerable pre-extensional magmatism in the NE Iranian plateau does not support magma underplating, subsequent thermal weakening and collapse as a mechanism for the extension in this region. It also indicates that the models that consider waning of volcanism as a controlling mechanism for triggering of extensional faulting (Sonder & Jones, 1999) is not applicable for this region. The amagmatic extension may reflect magma crystallization at depth due to reduced confining pressure resulted from active normal faulting and fracturing (Gans & Bohrson, 1998). The extension and related asthenospheric rise may be developed in a back-arc system.
Spherically symmetric solutions and gravitational collapse in brane-worlds
DOE Office of Scientific and Technical Information (OSTI.GOV)
Heydari-Fard, Malihe; Sepangi, Hamid R., E-mail: heydarifard@qom.ac.ir, E-mail: hr-sepangi@sbu.ac.ir
2009-02-15
We consider spherically symmetric solutions within the context of brane-world theory without mirror symmetry or any form of junction conditions. For a constant curvature bulk, we obtain the modified Tolman-Oppenheimer-Volkoff (TOV) interior solutions in two cases where one is matched to a schwarzschild-de Sitter exterior while the other is consistent with an exterior solution whose structure can be used to explain the galaxy rotation curves without postulating dark matter. We also find the upper bound to the mass of a static brane-world star and show that the influence of the bulk effects on the interior solutions is small. Finally, wemore » investigate the gravitational collapse on the brane and show that the exterior of a collapsing star can be static in this scenario.« less
Late Neanderthals at Jarama VI (central Iberia)?
NASA Astrophysics Data System (ADS)
Kehl, Martin; Burow, Christoph; Hilgers, Alexandra; Navazo, Marta; Pastoors, Andreas; Weniger, Gerd-Christian; Wood, Rachel; Jordá Pardo, Jesús F.
2013-09-01
Previous geochronological and archaeological studies on the rock shelter Jarama VI suggested a late survival of Neanderthals in central Iberia and the presence of lithic assemblages of Early Upper Paleolithic affinity. New data on granulometry, mineralogical composition, geochemical fingerprints and micromorphology of the sequence corroborate the previous notion that the archaeological units JVI.2.1 to JVI.2.3 are slackwater deposits of superfloods, which did not experience significant post-depositional changes, whereas the artifact-rich units JVI.3 and JVI.1 mainly received sediment inputs by sheetwash and cave spall. New AMS radiocarbon measurements on three samples of cut-marked bone using the ultrafiltration technique yielded ages close to, or beyond, the limit of radiocarbon dating at ca. 50 14C ka BP, and hence suggest much higher antiquity than assumed previously. Furthermore, elevated temperature post-IR IRSL luminescence measurements on K feldspars yielded burial ages for subunits JVI.2.2 and JVI.2.3 between 50 and 60 ka. Finally, our reappraisal of the stone industry strongly suggests that the whole sequence is of Mousterian affinity. In conclusion, Jarama VI most probably does not document a late survival of Neanderthals nor an Early Upper Paleolithic occupation in central Iberia, but rather indicates an occupation breakdown after the Middle Paleolithic.
Genetics Home Reference: hereditary myopathy with early respiratory failure
... Home Health Conditions HMERF Hereditary myopathy with early respiratory failure Printable PDF Open All Close All Enable ... expand/collapse boxes. Description Hereditary myopathy with early respiratory failure ( HMERF ) is an inherited muscle disease that ...
NASA Astrophysics Data System (ADS)
Sañé, E.; Isla, E.; Grémare, A.; Gutt, J.; Vétion, G.; DeMaster, D. J.
2011-01-01
In March 2002, 3200 km 2 of the Larsen B ice shelf collapsed off the Eastern Antarctic Peninsula (EAP). In the austral summer of 2006, sea floor sediment was recovered beneath the extinct Larsen B ice shelf and in a region off the Northern Antarctic Peninsula (NAP), which has been free of ice shelves for more than 1000 yr. To assess changes in the chemical composition of the sediment after ice shelf collapses, chlorophylls and pheophytins were measured in sediment cores at six stations. This is the first time that chlorophyll pigments have been analysed in sediment samples from regions under recently collapsed ice shelves. Five years after the ice shelf collapse, Chla and Chlc concentrations were similar in the interfacial sediment (upper 1 cm) of NAP and EAP regions. However, in EAP Chla and Chlc concentrations decreased more rapidly with depth in the sediment column and were negligible below 2 cm depth. The high Chla to Pheoa ratios indicated that sedimentary pigments found in EAP had undergone limited degradation suggesting that they were locally produced rather than laterally advected. Complementary information from excess 210Pb activity and diatom valve distributions provided further evidence that the pigment fluxes to the seabed in EAP took place only after the ice shelf collapse.
Constraints on the Progenitor of SN 2010jl and Pre-existing Hot Dust in its Surrounding Medium
NASA Technical Reports Server (NTRS)
Dwek, Eli; Arendt, Richard G.; Fox, Ori D.; Kelly, Patrick L.; Smith, Nathan; Van Dyk, Schuyler D.; Filippenko, Alexei, V.; Andrews, Jennifer; Shivvers, Isaac
2017-01-01
A search for the progenitor of SN 2010jl, an unusually luminous core-collapse supernova of Type IIn, using pre-explosion Hubble/WFPC2 and Spitzer/IRAC images of the region, yielded upper limits on the UV and near infrared (IR) fluxes from any candidate star. These upper limits constrain the luminosity and effective temperature of the progenitor, the mass of any pre-existing dust in its surrounding circumstellar medium (CSM), and dust proximity to the star. A lower limit on the CSM dust mass is required to hide a luminous progenitor from detection by Hubble. Upper limits on the CSM dust mass and constraints on its proximity to the star are set by requiring that the absorbed and reradiated IR emission not exceed the IRAC upper limits. Using the combined extinction-IR emission constraints, we present viable M(sub d)-R(sub 1) combinations, where M(sub d) and R(sub 1) are the CSM dust mass and its inner radius. These depend on the CSM outer radius, dust composition and grain size, and the properties of the progenitor. The results constrain the pre-supernova evolution of the progenitor, and the nature and origin of the observed post-explosion IR emission from SN 2010jl. In particular, an eta Car-type progenitor will require at least 4 mag of visual extinction to avoid detection by Hubble. This can be achieved with dust masses greater than approximately equal to 10(exp -3) solar mass (less than the estimated 0.2-0.5 solar mass around eta Car), which must be located at distances of greater than approximately equal to 10(exp 16) cm from the star to avoid detection by Spitzer.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Van Dyk, Schuyler D.; De Mink, Selma E.; Zapartas, Emmanouil
Core-collapse supernovae (SNe), which mark the deaths of massive stars, are among the most powerful explosions in the universe and are responsible, e.g., for a predominant synthesis of chemical elements in their host galaxies. The majority of massive stars are thought to be born in close binary systems. To date, putative binary companions to the progenitors of SNe may have been detected in only two cases, SNe 1993J and 2011dh. We report on the search for a companion of the progenitor of the Type Ic SN 1994I, long considered to have been the result of binary interaction. Twenty years aftermore » explosion, we used the Hubble Space Telescope to observe the SN site in the ultraviolet (F275W and F336W bands), resulting in deep upper limits on the expected companion: F275W > 26.1 mag and F336W > 24.7 mag. These allow us to exclude the presence of a main sequence companion with a mass ≳10 M{sub ⊙}. Through comparison with theoretical simulations of possible progenitor populations, we show that the upper limits to a companion detection exclude interacting binaries with semi-conservative (late Case A or early Case B) mass transfer. These limits tend to favor systems with non-conservative, late Case B mass transfer with intermediate initial orbital periods and mass ratios. The most likely mass range for a putative main sequence companion would be ∼5–12 M{sub ⊙}, the upper end of which corresponds to the inferred upper detection limit.« less
NASA Astrophysics Data System (ADS)
Huang, Chien-Jung; White, Susan M.; Huang, Shao-Ching; Mallya, Sanjay; Eldredge, Jeff D.
2014-11-01
Obstructive sleep apnea(OSA) is a medical condition characterized by repetitive partial or complete occlusion of the airway during sleep. The soft tissues in the airway of OSA patients are prone to collapse under the low pressure loads incurred during breathing. The numerical simulation with patient-specific upper airway model can provide assistance for diagnosis and treatment assessment. The eventual goal of this research is the development of numerical tool for air-tissue interactions in the upper airway of patients with OSA. This tool is expected to capture collapse of the airway in respiratory flow conditions, as well as the effects of various treatment protocols. Here, we present our ongoing progress toward this goal. A sharp-interface embedded boundary method is used on Cartesian grids for resolving the air-tissue interface in the complex patient-specific airway geometries. For the structure simulation, a cut-cell FEM is used. Non-linear Green strains are used for properly resolving the large tissue displacements in the soft palate structures. The fluid and structure solvers are strongly coupled. Preliminary results will be shown, including flow simulation inside the 3D rigid upper airway of patients with OSA, and several validation problem for the fluid-structure coupling.
Post discharge problems in women recovering from coronary artery bypass graft surgery.
Gallagher, Robyn; McKinley, Sharon; Dracup, Kathleen
2004-11-01
This study was conducted to describe the types and frequency of problems Australian women experience when recovering at home in the first 6 weeks following coronary artery bypass graft (CABG) surgery and the relationship between symptom experience and psychological distress. A convenience sample of 52 women (mean age 66.31 years, range 53-79 years) who had uncomplicated CABG surgery was selected from two tertiary hospitals in Sydney. A descriptive design was used with information related to post-operative problems collected by telephone interview at 1, 3 and 6 weeks post discharge using a semistructured questionnaire. Psychological distress was assessed at 12 weeks post discharge using the Hospital Anxiety and Depression Scale (HADS). Responses were categorised, collapsed and described using frequencies and percentages. Relationships were assessed by Spearman's r. The most common problems in the first and third weeks post discharge were sleeplessness and nausea or poor appetite and chest incision pain. Although problems improved over the first 6 weeks post-operatively, approximately one-quarter of the women still reported chest incision pain and almost 40% reported problems with leg wounds and oedema. The number of problems experienced at 6 weeks was significantly correlated with depression at 12 weeks. These findings support the importance of a preoperative education programme that includes anticipation of physical problems in the immediate post-operative period and a follow-up of female patients in the early transition period following hospital discharge.
NASA Astrophysics Data System (ADS)
Steinmann, Lena; Spiess, Volkhard; Sacchi, Marco
2018-01-01
In this study we present the first 3D high-resolution multichannel seismic dataset from a (partly) submerged caldera setting, the Campi Flegrei caldera (CFc). Our work aims at examining the spatial and temporal evolution of the CFc since the last caldera-forming event, the Neapolitan Yellow Tuff (NYT, 15 ka) eruption. The main objectives are to investigate the caldera's shallow (< 200 m) subsurface structure and post-NYT-collapse (< 15 ka) deformational processes, the manifestation of magmatic and hydrothermal processes in the subsurface, as well as the volume, dispersal and explosivity of coastal post-collapse eruptions, thereby significantly advancing our current knowledge of the CFc. Our findings confirm the existence of a nested-caldera system comprising two caldera depressions bordered by an inner and a deeper (> 200 m) outer caldera ring-fault zone. The seismic data revealed that the NYT collapse occurred exclusively along the inner caldera ring-fault and that the related NYT caldera depression is filled with on average 61 m of sediment deposited between 15 and 8.6 ka. The geometry of the inner ring-fault, consisting of four fault segments, seems to be strongly influenced by regional NW-SE and NE SW-trending faults. Furthermore, we found that the ring-faults have acted as pathway for the recent (< 3.7 ka) ascent of fluids (gases and liquids) and the emplacement of intrusions. We propose that the outer ring-fault zone, which likely formed in the course of the Campanian Ignimbrite (CI, 39 ka) eruption, has had the main control on the release and ascent of fluids. Overall, the caldera ring-faults represent key locations for the interconnection between the magmatic-hydrothermal systems and the surface and, thus, potentially represent future eruption sites as well as important fluid pathways during the recent unrest episodes. Furthermore, we reassessed the volume, dispersal, and explosivity of the post-collapse Nisida Bank (10.3-9.5 ka), Nisida Island ( 3.98 ka), and Capo Miseno (3.7 ka) eruptions, yielding DRE values of 0.15 km3, 0.1 km3, and 0.08 km3, respectively, and an explosive magnitude of at least moderate-large scale (VEI 3). Our findings highlight that eruption volumes may be underestimated by 3 to 4 times if the submerged portion of a (partly) submerged caldera is not considered, implying severe consequences for the hazard and risk evaluation. The spatial response of the post-collapse (< 15 ka) depositional environment to volcanic activity, deformational processes and sea-level variations is presented in a comprehensive 3D evolutionary model.
Landry, Shane A; Joosten, Simon A; Sands, Scott A; White, David P; Malhotra, Atul; Wellman, Andrew; Hamilton, Garun S; Edwards, Bradley A
2017-08-01
Upper airway collapsibility predicts the response to several non-continuous positive airway pressure (CPAP) interventions for obstructive sleep apnoea (OSA). Measures of upper airway collapsibility cannot be easily performed in a clinical context; however, a patient's therapeutic CPAP requirement may serve as a surrogate measure of collapsibility. The present work aimed to compare the predictive use of CPAP level with detailed physiological measures of collapsibility. Therapeutic CPAP levels and gold-standard pharyngeal collapsibility measures (passive pharyngeal critical closing pressure (P crit ) and ventilation at CPAP level of 0 cmH 2 O (V passive )) were retrospectively analysed from a randomized controlled trial (n = 20) comparing the combination of oxygen and eszopiclone (treatment) versus placebo/air control. Responders (9/20) to treatment were defined as those who exhibited a 50% reduction in apnoea/hypopnoea index (AHI) plus an AHI<15 events/h on-therapy. Responders to treatment had a lower therapeutic CPAP requirement compared with non-responders (6.6 (5.4-8.1) cmH 2 O vs 8.9 (8.4-10.4) cmH 2 O, P = 0.007), consistent with their reduced collapsibility (lower P crit , P = 0.017, higher V passive P = 0.025). Therapeutic CPAP level provided the highest predictive accuracy for differentiating responders from non-responders (area under the curve (AUC) = 0.86 ± 0.9, 95% CI: 0.68-1.00, P = 0.007). However, both P crit (AUC = 0.83 ± 0.11, 95% CI: 0.62-1.00, P = 0.017) and V passive (AUC = 0.77 ± 0.12, 95% CI: 0.53-1.00, P = 0.44) performed well, and the difference in AUC for these three metrics was not statistically different. A therapeutic CPAP level ≤8 cmH 2 O provided 78% sensitivity and 82% specificity (positive predictive value = 78%, negative predictive value = 82%) for predicting a response to these therapies. Therapeutic CPAP requirement, as a surrogate measure of pharyngeal collapsibility, predicts the response to non-anatomical therapy (oxygen and eszopiclone) for OSA. © 2017 Asian Pacific Society of Respirology.
NASA Astrophysics Data System (ADS)
Cunningham, K. J.; Walker, C.; Westcott, R. L.
2011-12-01
Continuous improvements in shallow-focused, high-resolution, marine seismic-reflection technology has provided the opportunity to evaluate geologic structures that breach confining units of the Floridan aquifer system within the southeastern Florida Platform. The Floridan aquifer system is comprised mostly of Tertiary platform carbonates. In southeastern Florida, hydrogeologic confinement is important to sustainable use of the Floridan aquifer system, where the saline lower part is used for injection of wastewater and the brackish upper part is an alternative source of drinking water. Between 2007 and 2011, approximately 275 km of 24- and 48-channel seismic-reflection profiles were acquired in canals of peninsular southeastern Florida, Biscayne Bay, present-day Florida shelf margin, and the deeply submerged Miami Terrace. Vertical to steeply dipping offsets in seismic reflections indicate faults, which range from Eocene to possible early Pliocene age. Most faults are associated with karst collapse structures; however, a few tectonic faults of early Miocene to early Pliocene age are present. The faults may serve as a pathway for vertical groundwater flow across relatively low-permeability carbonate strata that separate zones of regionally extensive high-permeability in the Floridan aquifer system. The faults may collectively produce a regional confinement bypass system. In early 2011, twenty seismic-reflection profiles were acquired near the Key Biscayne submarine sinkhole located on the seafloor of the Miami Terrace. Here the water depth is about 365 m. A steeply dipping (eastward) zone of mostly deteriorated quality of seismic-reflection data underlies the sinkhole. Correlation of coherent seismic reflections within and adjacent to the disturbed zone indicates a series of faults occur within the zone. It is hypothesized that upward movement of groundwater within the zone contributed to development of a hypogenic karst system and the resultant overlying sinkhole. Study of this modern seafloor sinkhole may provide clues to the genesis of the more deeply buried Tertiary karst collapse structures. Three-dimensional geomodeling of the seismic-reflection data from the Key Biscayne sinkhole further aids visualization of the seismic stratigraphy and structural system that underlies the sinkhole.
Galileo at Io: results from high-resolution imaging.
McEwen, A S; Belton, M J; Breneman, H H; Fagents, S A; Geissler, P; Greeley, R; Head, J W; Hoppa, G; Jaeger, W L; Johnson, T V; Keszthelyi, L; Klaasen, K P; Lopes-Gautier, R; Magee, K P; Milazzo, M P; Moore, J M; Pappalardo, R T; Phillips, C B; Radebaugh, J; Schubert, G; Schuster, P; Simonelli, D P; Sullivan, R; Thomas, P C; Turtle, E P; Williams, D A
2000-05-19
During late 1999/early 2000, the solid state imaging experiment on the Galileo spacecraft returned more than 100 high-resolution (5 to 500 meters per pixel) images of volcanically active Io. We observed an active lava lake, an active curtain of lava, active lava flows, calderas, mountains, plateaus, and plains. Several of the sulfur dioxide-rich plumes are erupting from distal flows, rather than from the source of silicate lava (caldera or fissure, often with red pyroclastic deposits). Most of the active flows in equatorial regions are being emplaced slowly beneath insulated crust, but rapidly emplaced channelized flows are also found at all latitudes. There is no evidence for high-viscosity lava, but some bright flows may consist of sulfur rather than mafic silicates. The mountains, plateaus, and calderas are strongly influenced by tectonics and gravitational collapse. Sapping channels and scarps suggest that many portions of the upper approximately 1 kilometer are rich in volatiles.
Delineation of a collapse feature in a noisy environment using a multichannel surface wave technique
Xia, J.; Chen, C.; Li, P.H.; Lewis, M.J.
2004-01-01
A collapse developed at Calvert Cliffs Nuclear Power Plant, Maryland, in early 2001. The location of the collapse was over a groundwater drainage system pipe buried at an elevation of +0??9 m (reference is to Chesapeake Bay level). The cause of the collapse was a subsurface drain pipe that collapsed because of saltwater corrosion of the corrugated metal pipe. The inflow/outflow of sea water and groundwater flow caused soil to be removed from the area where the pipe collapsed. To prevent damage to nearby structures, the collapse was quickly filled with uncompacted sand and gravel (???36000 kg). However, the plant had an immediate need to determine whether more underground voids existed. A high-frequency multichannel surface-wave survey technique was conducted to define the zone affected by the collapse. Although the surface-wave survey at Calvert Cliffs Nuclear Power Plant was conducted at a noise level 50-100 times higher than the normal environment for a shallow seismic survey, the shear (S)-wave velocity field calculated from surface-wave data delineated a possible zone affected by the collapse. The S-wave velocity field showed chimney-shaped low-velocity anomalies that were directly related to the collapse. Based on S-wave velocity field maps, a potential zone affected by the collapse was tentatively defined.
Khan, Ahmed; Chuenpagdee, Ratana
2014-09-01
Rebuilding collapsed fisheries is a multifaceted problem, requiring a holistic governance approach rather than technical management fixes. Using the Northern Gulf cod case study in eastern Canada, we illustrate how a "fish chain" framework, drawn from the interactive governance perspective, is particularly helpful in analyzing rebuilding challenges. The analysis demonstrates that factors limiting rebuilding exist along the entire fish chain, i.e., the pre-harvest, harvest, and post-harvest stages. These challenges are embedded in both the ecological and social systems associated with the Northern Gulf cod fisheries, as well as in the governing systems. A comparative analysis of the pre- and post-collapse of the cod fisheries also reveals governance opportunities in rebuilding, which lie in policy interventions such as integrated and ecosystem-based management, livelihood transitional programs, and cross-scale institutional arrangements. Lessons from the Northern Gulf cod case study, especially the missed opportunities to explore alternative governing options during the transition, are valuable for rebuilding other collapsed fisheries.
Building Damage Extraction Triggered by Earthquake Using the Uav Imagery
NASA Astrophysics Data System (ADS)
Li, S.; Tang, H.
2018-04-01
When extracting building damage information, we can only determine whether the building is collapsed using the post-earthquake satellite images. Even the satellite images have the sub-meter resolution, the identification of slightly damaged buildings is still a challenge. As the complementary data to satellite images, the UAV images have unique advantages, such as stronger flexibility and higher resolution. In this paper, according to the spectral feature of UAV images and the morphological feature of the reconstructed point clouds, the building damage was classified into four levels: basically intact buildings, slightly damaged buildings, partially collapsed buildings and totally collapsed buildings, and give the rules of damage grades. In particular, the slightly damaged buildings are determined using the detected roof-holes. In order to verify the approach, we conduct experimental simulations in the cases of Wenchuan and Ya'an earthquakes. By analyzing the post-earthquake UAV images of the two earthquakes, the building damage was classified into four levels, and the quantitative statistics of the damaged buildings is given in the experiments.
Gera, D N; Shah, M K; Ghodela, V A; Kute, V B; Trivedi, H L
2017-01-01
Well-recognized association between HIV 1 infection and collapsing glomerulopathy (CG) raises the possibility that intrarenal infection by other viruses may also contribute to the development of this lesion in native or post-transplant kidneys. There is evidence in literature about association of these lesions with cytomegalovirus, Epstein-Barr virus, hepatitis C virus, and parvovirus B19 infections. Here, we present a case report of post-transplant BK virus nephropathy in a male child who was found to have CG in subsequent biopsy 2 months later. His renal function and proteinuria were stabilized on elimination of viremia.
1993-01-01
effect of cisapride on the symptoms of unexplained upper abdominal pain, nausea, vomiting, anorexia, early satiety, bloating/ distension in patients with...for 30 minutes following eccentric exercise will less the 3 indices of delayed-onset muscle soreness (DOMS): perceived muscular soreness, reduced...post-exercise and the Talag Pain Rating Scale will be used to assess muscular soreness. Progress: No progress report was furnished by the principal
Sañé, Elisabet; Isla, Enrique; Bárcena, María Ángeles; DeMaster, David J
2013-01-01
In 2002, section B of the Larsen ice shelf, off of the Eastern Antarctic Peninsula, collapsed and created the opportunity to study whether the changes at the sea surface left evidence in the sedimentary record. Biogenic silica is major constituent of Antarctic marine sediment, and its presence in the sediment column is associated with diatom production in the euphotic zone. The abundance of diatom valves and the number of sponge spicules in the biogenic silica was analyzed to determine how the origin of the biogenic silica in the upper layers of the sediment column responded to recent environmental changes. Diatom valves were present only in the upper 2 cm of sediment, which roughly corresponds to the period after the collapse of the ice shelf. In contrast, sponge spicules, a more robust form of biogenic silica, were also found below the upper 2 cm layer of the sediment column. Our results indicate that in this region most of the biogenic silica in the sedimentary record originated from sponge spicules rather than diatoms during the time when the sea surface was covered by the Larsen ice shelf. Since the collapse of the ice shelf, the development of phytoplankton blooms and the consequent influx of diatom debris to the seabed have shifted the biogenic silica record to one dominated by diatom debris, as occurs in most of the Antarctic marine sediment. This shift provides further evidence of the anthropogenic changes to the benthic habitats of the Antarctic and will improve the interpretation of the sedimentary record in Polar Regions where these events occur.
NASA Astrophysics Data System (ADS)
Hassan, M.; Abu-Alam, T. S.; Hauzenberger, C.; Stüwe, K.
2016-10-01
Late Precambrian intrusive rocks in the Arabian-Nubian Shield emplaced within and around the Najd Fault System of Saudi Arabia feature a great compositional diversity and a variety of degrees of deformation (i.e. pre-shearing deformed, sheared mylonitized, and post-shearing undeformed) that allows placing them into a relative time order. It is shown here that the degree of deformation is related to compositional variations where early, usually pre-shearing deformed rocks are of dioritic, tonalitic to granodioritic, and later, mainly post-shearing undeformed rocks are mostly of granitic composition. Correlation of the geochemical signature and time of emplacement is interpreted in terms of changes in the source region of the produced melts due to the change of the stress regime during the tectonic evolution of the Arabian-Nubian Shield. The magma of the pre-shearing rocks has tholeiitic and calc-alkaline affinity indicating island arc or continental arc affinity. In contrast, the syn- and post-shearing rocks are mainly potassium rich peraluminous granites which are typically associated with post-orogenic uplift and collapse. This variation in geochemical signature is interpreted to reflect the change of the tectonic regime from a compressional volcanic arc nature to extensional within-plate setting of the Arabian-Nubian Shield. Within the context of published geochronological data, this change is likely to have occurred around 605-580 Ma.
NASA Astrophysics Data System (ADS)
Qin, Yu; Feng, Qiao; Chen, Gang; Chen, Yan; Zou, Kaizhen; Liu, Qian; Jiao, Qianqian; Zhou, Dingwu; Pan, Lihui; Gao, Jindong
2018-05-01
The Maoniushan Formation in the northern part of the North Qaidam Orogen (NQO), NW China, contains key information on a Paleozoic change in tectonic setting of the NQO from compression to extension. Here, new zircon U-Pb, petrological, and sedimentological data for the lower molasse sequence of the Maoniushan Formation are used to constrain the timing of this tectonic transition. Detrital zircons yield U-Pb ages of 3.3-0.4 Ga with major populations at 0.53-0.4, 1.0-0.56, 2.5-1.0, and 3.3-2.5 Ga. The maximum depositional age of the Maoniushan Formation is well constrained by a youngest detrital zircon age of ∼409 Ma. Comparing these dates with geochronological data for the region indicates that Proterozoic-Paleozoic zircons were derived mainly from the NQO as well as the Oulongbuluk and Qaidam blocks, whereas Archean zircons were probably derived from the Oulongbuluk Block and the Tarim Craton. The ∼924, ∼463, and ∼439 Ma tectonothermal events recorded in this region indicate that the NQO was involved in the early Neoproterozoic assembly of Rodinia and early Paleozoic microcontinental convergence. A regional angular unconformity between Devonian and pre-Devonian strata within the NQO suggests a period of strong mountain building between the Oulongbuluk and Qaidam blocks during the Silurian, whereas an Early Devonian post-orogenic molasse, evidence of extensional collapse, and Middle to Late Devonian bimodal volcanic rocks and Carboniferous marine carbonate rocks clearly reflect long-lived tectonic extension. Based on these results and the regional geology, we suggest that the Devonian volcano-sedimentary rocks within the NQO were formed in a post-orogenic extensional setting similar to that of the East Kunlun Orogen, indicating that a major tectonic transition from compression to extension in these two orogens probably commenced in the Early Devonian.
A child with a difficult airway: what do I do next?
Engelhardt, Thomas; Weiss, Markus
2012-06-01
Difficulties in pediatric airway management are common and continue to result in significant morbidity and mortality. This review reports on current concepts in approaching a child with a difficult airway. Routine airway management in healthy children with normal airways is simple in experienced hands. Mask ventilation (oxygenation) is always possible and tracheal intubation normally simple. However, transient hypoxia is common in these children usually due to unexpected anatomical and functional airway problems or failure to ventilate during rapid sequence induction. Anatomical airway problems (upper airway collapse and adenoid hypertrophy) and functional airway problems (laryngospasm, bronchospasm, insufficient depth of anesthesia and muscle rigidity, gastric hyperinflation, and alveolar collapse) require urgent recognition and treatment algorithms due to insufficient oxygen reserves. Early muscle paralysis and epinephrine administration aids resolution of these functional airway obstructions. Children with an 'impaired' normal (foreign body, allergy, and inflammation) or an expected difficult (scars, tumors, and congenital) airway require careful planning and expertise. Training in the recognition and management of these different situations as well as a suitably equipped anesthesia workstation and trained personnel are essential. The healthy child with an unexpected airway problem requires clear strategies. The 'impaired' normal pediatric airway may be handled by anesthetists experienced with children, whereas the expected difficult pediatric airway requires dedicated pediatric anesthesia specialist care and should only be managed in specialized centers.
Stress evolution during caldera collapse
NASA Astrophysics Data System (ADS)
Holohan, E. P.; Schöpfer, M. P. J.; Walsh, J. J.
2015-07-01
The mechanics of caldera collapse are subject of long-running debate. Particular uncertainties concern how stresses around a magma reservoir relate to fracturing as the reservoir roof collapses, and how roof collapse in turn impacts upon the reservoir. We used two-dimensional Distinct Element Method models to characterise the evolution of stress around a depleting sub-surface magma body during gravity-driven collapse of its roof. These models illustrate how principal stress orientations rotate during progressive deformation so that roof fracturing transitions from initial reverse faulting to later normal faulting. They also reveal four end-member stress paths to fracture, each corresponding to a particular location within the roof. Analysis of these paths indicates that fractures associated with ultimate roof failure initiate in compression (i.e. as shear fractures). We also report on how mechanical and geometric conditions in the roof affect pre-failure unloading and post-failure reloading of the reservoir. In particular, the models show how residual friction within a failed roof could, without friction reduction mechanisms or fluid-derived counter-effects, inhibit a return to a lithostatically equilibrated pressure in the magma reservoir. Many of these findings should be transferable to other gravity-driven collapse processes, such as sinkhole formation, mine collapse and subsidence above hydrocarbon reservoirs.
a Statistical Texture Feature for Building Collapse Information Extraction of SAR Image
NASA Astrophysics Data System (ADS)
Li, L.; Yang, H.; Chen, Q.; Liu, X.
2018-04-01
Synthetic Aperture Radar (SAR) has become one of the most important ways to extract post-disaster collapsed building information, due to its extreme versatility and almost all-weather, day-and-night working capability, etc. In view of the fact that the inherent statistical distribution of speckle in SAR images is not used to extract collapsed building information, this paper proposed a novel texture feature of statistical models of SAR images to extract the collapsed buildings. In the proposed feature, the texture parameter of G0 distribution from SAR images is used to reflect the uniformity of the target to extract the collapsed building. This feature not only considers the statistical distribution of SAR images, providing more accurate description of the object texture, but also is applied to extract collapsed building information of single-, dual- or full-polarization SAR data. The RADARSAT-2 data of Yushu earthquake which acquired on April 21, 2010 is used to present and analyze the performance of the proposed method. In addition, the applicability of this feature to SAR data with different polarizations is also analysed, which provides decision support for the data selection of collapsed building information extraction.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-01
.... 3. With the airplane in level attitude and in each attitude resulting from the collapse of one or... during all flight phases. 14. ``No smoking'' and ``return to seat'' signs must be installed and visible...
Gravitational-Wave Luminosity of Binary Neutron Stars Mergers
NASA Astrophysics Data System (ADS)
Zappa, Francesco; Bernuzzi, Sebastiano; Radice, David; Perego, Albino; Dietrich, Tim
2018-03-01
We study the gravitational-wave peak luminosity and radiated energy of quasicircular neutron star mergers using a large sample of numerical relativity simulations with different binary parameters and input physics. The peak luminosity for all the binaries can be described in terms of the mass ratio and of the leading-order post-Newtonian tidal parameter solely. The mergers resulting in a prompt collapse to black hole have the largest peak luminosities. However, the largest amount of energy per unit mass is radiated by mergers that produce a hypermassive neutron star or a massive neutron star remnant. We quantify the gravitational-wave luminosity of binary neutron star merger events, and set upper limits on the radiated energy and the remnant angular momentum from these events. We find that there is an empirical universal relation connecting the total gravitational radiation and the angular momentum of the remnant. Our results constrain the final spin of the remnant black hole and also indicate that stable neutron star remnant forms with super-Keplerian angular momentum.
Gravitational-Wave Luminosity of Binary Neutron Stars Mergers.
Zappa, Francesco; Bernuzzi, Sebastiano; Radice, David; Perego, Albino; Dietrich, Tim
2018-03-16
We study the gravitational-wave peak luminosity and radiated energy of quasicircular neutron star mergers using a large sample of numerical relativity simulations with different binary parameters and input physics. The peak luminosity for all the binaries can be described in terms of the mass ratio and of the leading-order post-Newtonian tidal parameter solely. The mergers resulting in a prompt collapse to black hole have the largest peak luminosities. However, the largest amount of energy per unit mass is radiated by mergers that produce a hypermassive neutron star or a massive neutron star remnant. We quantify the gravitational-wave luminosity of binary neutron star merger events, and set upper limits on the radiated energy and the remnant angular momentum from these events. We find that there is an empirical universal relation connecting the total gravitational radiation and the angular momentum of the remnant. Our results constrain the final spin of the remnant black hole and also indicate that stable neutron star remnant forms with super-Keplerian angular momentum.
NASA Technical Reports Server (NTRS)
2006-01-01
6 April 2006 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows the edge (running diagonally from the lower left to the upper right) of a trough, which is part of a large pit crater complex in Noachis Terra. This type of trough forms through the collapse of surface materials into the subsurface, and often begins as a series of individual pit craters. Over time, continued collapse increases the diameter of individual pits until finally, adjacent pits merge to form a trough such as the one captured in this image. The deep shadowed area is caused in part by an overhang; layered rock beneath this overhang is less resistant to erosion, and thus has retreated tens of meters backward, beneath the overhang. A person could walk up inside this 'cave' formed by the overhanging layered material. Location near: 47.0oS, 355.7oW Image width: 3 km (1.9 mi) Illumination from: upper left Season: Southern SummerEVIDENCE FOR A COMPACT WOLF-RAYET PROGENITOR FOR THE TYPE Ic SUPERNOVA PTF 10vgv
DOE Office of Scientific and Technical Information (OSTI.GOV)
Corsi, A.; Ofek, E. O.; Gal-Yam, A.
We present the discovery of PTF 10vgv, a Type Ic supernova (SN) detected by the Palomar Transient Factory, using the Palomar 48 inch telescope (P48). R-band observations of the PTF 10vgv field with P48 probe the SN emission from its very early phases (about two weeks before R-band maximum) and set limits on its flux in the week prior to the discovery. Our sensitive upper limits and early detections constrain the post-shock-breakout luminosity of this event. Via comparison to numerical (analytical) models, we derive an upper-limit of R {approx}< 4.5 R{sub Sun} (R {approx}< 1 R{sub Sun }) on themore » radius of the progenitor star, a direct indication in favor of a compact Wolf-Rayet star. Applying a similar analysis to the historical observations of SN 1994I yields R {approx}< 1/4 R{sub Sun} for the progenitor radius of this SN.« less
Free style perforator based propeller flaps: Simple solutions for upper extremity reconstruction!
Panse, Nikhil; Sahasrabudhe, Parag
2014-01-01
The introduction of perforator flaps by Koshima et al. was met with much animosity in the plastic surgery fraternity. The safety concerns of these flaps following the intentional twist of the perforators have prevented widespread adoption of this technique. Use of perforator based propeller flaps in the lower extremity is gradually on the rise, but their use in upper extremity reconstruction is infrequently reported, especially in the Indian subcontinent. We present a retrospective series of 63 free style perforator flaps used for soft tissue reconstruction of the upper extremity from November 2008 to June 2013. Flaps were performed by a single surgeon for various locations and indications over the upper extremity. Patient demographics, surgical indication, defect features, complications and clinical outcome are evaluated and presented as an uncontrolled case series. 63 free style perforator based propeller flaps were used for soft tissue reconstruction of 62 patients for the upper extremity from November 2008 to June 2013. Of the 63 flaps, 31 flaps were performed for trauma, 30 for post burn sequel, and two for post snake bite defects. We encountered flap necrosis in 8 flaps, of which there was complete necrosis in 4 flaps, and partial necrosis in four flaps. Of these 8 flaps, 7 needed a secondary procedure, and one healed secondarily. Although we had a failure rate of 12-13%, most of our failures were in the early part of the series indicative of a learning curve associated with the flap. Free style perforator based propeller flaps are a reliable option for coverage of small to moderate sized defects. Therapeutic IV.
Shi, Jingsheng; Chen, Jie; Wu, Jianguo; Chen, Feiyan; Huang, Gangyong; Wang, Zhan; Zhao, Guanglei; Wei, Yibing; Wang, Siqun
2014-01-01
Background The aim of this study was to contrast the collapse values of the postoperative weight-bearing areas of different tantalum rod implant positions, fibula implantation, and core decompression model and to investigate the advantages and disadvantages of tantalum rod implantation in different ranges of osteonecrosis in comparison with other methods. Material/Methods The 3D finite element method was used to establish the 3D finite element model of normal upper femur, 3D finite element model after tantalum rod implantation into different positions of the upper femur in different osteonecrosis ranges, and other 3D finite element models for simulating fibula implant and core decompression. Results The collapse values in the weight-bearing area of the femoral head of the tantalum rod implant model inside the osteonecrosis area, implant model in the middle of the osteonecrosis area, fibula implant model, and shortening implant model exhibited no statistically significant differences (p>0.05) when the osteonecrosis range was small (60°). The stress values on the artificial bone surface for the tantalum rod implant model inside the osteonecrosis area and the shortening implant model exhibited statistical significance (p<0.01). Conclusions Tantalum rod implantation into the osteonecrosis area can reduce the collapse values in the weight-bearing area when osteonecrosis of the femoral head (ONFH) was in a certain range, thereby obtaining better clinical effects. When ONFH was in a large range (120°), the tantalum rod implantation inside the osteonecrosis area, shortening implant or fibula implant can reduce the collapse values of the femoral head, as assessed by other methods. PMID:25479830
Nuclear reactor internals alignment configuration
Gilmore, Charles B [Greensburg, PA; Singleton, Norman R [Murrysville, PA
2009-11-10
An alignment system that employs jacking block assemblies and alignment posts around the periphery of the top plate of a nuclear reactor lower internals core shroud to align an upper core plate with the lower internals and the core shroud with the core barrel. The distal ends of the alignment posts are chamfered and are closely received within notches machined in the upper core plate at spaced locations around the outer circumference of the upper core plate. The jacking block assemblies are used to center the core shroud in the core barrel and the alignment posts assure the proper orientation of the upper core plate. The alignment posts may alternately be formed in the upper core plate and the notches may be formed in top plate.
Evolution of a Miocene sag basin in the Alboran Sea
NASA Astrophysics Data System (ADS)
Do Couto, D.; Gorini, C.; Jolivet, L.; Letouzey, J.; Smit, J.; d'Acremont, E.; Auxietre, J. L.; Le Pourhiet, L.; Estrada, F.; Elabassi, M.; Ammar, A.; Jabour, H.; Vendeville, B.
2012-04-01
The Alboran domain represents the westernmost termination of the peri-Mediterranean Alpine orogen. Its arcuate shape, delimited to the North by the Betic range and to the South by the Rif range, is the result of subduction, collision and slab migration processes. During the Neogene, several sedimentary basins formed on the Betics metamorphic basement, mainly due to the extensional collapse of the previously thickened crust of the Betic-Rif belt. The major sedimentary depocentre, the Western Alboran Basin (WAB), is surrounded by the Gibraltar arc, the volcanic Djibouti mounts and the Alboran ridge, and is partly affected by shale tectonics and associated mud volcanism. High-quality 2-D seismic profiles acquired along the Moroccan margin during the last decade reveal a complete history of the basin. Our study deals with the analysis of seismic profiles oriented parallel and orthogonal to the Mediterranean Moroccan margin. The stratigraphy was calibrated using well data from offshore Spain and Morocco. Our study focuses particularly on the tectono-stratigraphic reconstruction of the basin. The formation of the WAB began in the Early Miocene (Aquitanian - Burdigalian). A massive unit of Early Miocene to Lower Langhian shales and olistostromes forms a thick mobile décollement layer that controls and accommodates deformation of the basin fill. From the Upper Langhian to the Upper Tortonian, the basin is filled by a thick sequence of siliciclastic deposits. Stratigraphic geometries identified on seismic data clearly indicate that deformation of the basin fill started during deposition of Upper Langhian to the Upper Tortonian clastics. Shale tectonic deformation was re-activated recently, during the Messinian desiccation of the Mediterranean Sea (and the following catastrophic Pliocene reflooding) or during the Quaternary contourite deposition The sedimentary layers gently dip towards the basin centre and "onlaps" onto the basin margin, especially onto the basement high that bounds the basin toward the East. The contacts observed between the sediment and the basement reflectors are purely stratigraphic. These observations confirm that the geometry is essentially that of a sag basin. We discuss all these stratigraphic observations in the scope of the geodynamic evolution of the eastern and western Alboran basin and the extension recorded onshore during the basin development time interval.
Evolutionary trends of stature in upper Paleolithic and Mesolithic Europe.
Formicola, V; Giannecchini, M
1999-03-01
Long bone lengths of all available European Upper Paleolithic (41 males, 25 females) and Mesolithic (171 males, 118 females) remains have been transformed into stature estimates by means of new regression equations derived from Early Holocene skeletal samples using "Fully's anatomical stature" and the major axis regression technique (Formicola & Franceschi, 1996). Statistical analysis of the data, with reference both to time and space parameters, indicates that: (1) Early Upper Paleolithic samples (pre-Glacial Maximum) are very tall; (2) Late Upper Paleolithic groups (post-Glacial Maximum) from Western Europe, compared to their ancestors, show a marked decrease in height; (3) a further, although not significant, reduction of stature affects Western Mesolithics; (4) no regional differences have been observed during both phases of the Upper Paleolithic; (5) a high level of homogeneity has also been found in the Mesolithic, both in Western and Eastern Europe; (6) the internal homogeneity found during the Mesolithic in Western and Eastern Europe is associated with marked inter-regional variability, with populations of the latter region showing systematically significantly greater stature than their Western contemporaries. Evaluation of possible causes for the great stature of the Early Upper Paleolithic samples points to high nutritional standards as the most important factor. Results obtained on later groups clearly indicate that the Last Glacial Maximum, rather than the Mesolithic transition, is the critical phase in the negative trend affecting Western European populations. While changes in the quality of the diet, and in particular decreased protein intake, provide a likely explanation for that trend, variations in levels of gene flow probably also played a role. Reasons for the West-East Mesolithic dichotomy remain unclear and lack of information for the Late Upper Paleolithic of Eastern Europe prevents insight into the remote origins of this phenomenon. Analysis of regional differentiation of stature, particularly well supported by data from Mesolithic sites, points to the absence of today's latitudinal gradients and suggests a relative homogeneity in dietary, cultural and biodemographic patterns for the last hunter-gatherer populations of Western Europe. Copyright 1999 Academic Press.
Physiotherapy in upper abdominal surgery - what is current practice in Australia?
Patman, Shane; Bartley, Alice; Ferraz, Allex; Bunting, Cath
2017-01-01
Upper abdominal surgery (UAS) has the potential to cause post-operative pulmonary complications (PPCs). In the absence of high-quality research regarding post-operative physiotherapy management, consensus-based best practice guidelines formulated by Hanekom et al. (2012) are available to clinicians providing recommendations for post-UAS treatment. Such best practice guidelines have recommended that physiotherapists should be using early mobilisation and respiratory intervention to minimise risk of PPCs. However, recent evidence supports the implementation of mobilisation as a standalone treatment in PPC prevention, though the diversity in literature poses questions regarding ideal current practice. This project aimed to document and report the assessment measures and interventions physiotherapists are utilising following UAS, establishing whether current management is reflective of best practice guidelines and recent evidence. An online survey was completed by 57 experienced Australian physiotherapists working with patients following UAS (35% survey response rate, 63% completion rate). On day one following UAS, when a patient's condition is not medically limited, most physiotherapists routinely mobilise. Additionally, routine chest treatment continues to be implemented, with only 23% ( n = 11/47) of physiotherapists mobilising patients without accompanying specific respiratory intervention. Variability of screening tools used to identify post-operative patients at high risk of PPC development was evident. Patient-dependent factors such as 'fatigue' and 'non-compliance' were among those identified as barriers to treatment, all influencing the commencement of treatment. Physiotherapists indicated that early mobilisation away from the bedside was the preferred post-operative treatment within the UAS patient population. Many continue to perform routine respiratory interventions despite recent literature suggesting it may provide no additional benefit to preventing PPCs. Current intervention choice is reflective of guidelines [1], however, recent literature has called this into question and more research needs to be done to establish if these recommendations are the most effective at reducing PPCs. Continued research is necessary to promote translation of knowledge to ensure physiotherapists are mobilising patients day one post-UAS. Likewise, future work should focus on identification of barriers, the strategies used to overcome limitations and the creation of a reliable and validated screening tool to ensure appropriate prioritisation and allocation of physiotherapy resources within the UAS patient population.
MRI Evaluation of Post Core Decompression Changes in Avascular Necrosis of Hip
Marupaka, Sravan Kumar; Alluri, Swathi; MD, Naseeruddin; Irfan, Kazi Amir; Jampala, Venkateshwarlu; Apsingi, Sunil; Eachempati, Krishna Kiran
2015-01-01
Introduction Avascular necrosis of hip typically presents in young patients. Core decompression in precollapse stage provides pain relief and preservation of femoral head. The results of core decompression vary considerably despite early diagnosis. The role of MRI in monitoring patients post surgically has not been clearly defined. Aim To study pre and post core decompression MRI changes in avascular necrosis of hip. Materials and Methods This is a contiguous observational cohort of 40 hips treated by core decompression for precollapse avascular necrosis of femoral head, who had a baseline MRI performed before surgery. Core decompression of the femoral head was performed within 4 weeks. Follow up radiograph and MRI scans were done at six months. Harris hip score preoperatively, 1 month and 6 months after the surgery was noted. Success in this study was defined as postoperative increase in Harris hip score (HHS) by 20 points and no additional femoral collapse. End point of clinical adverse outcome as defined by fall in Harris hip score was conversion or intention to convert to total hip replacement (THR). MRI parameters in the follow up scan were compared to the preoperative MRI. Effect of core decompression on bone marrow oedema and femoral head collapse was noted. Results were analysed using SPSS software version. Results Harris hip score improved from 57 to 80 in all patients initially. Six hips had a fall in Harris hip score to mean value of 34.1 during follow up (9 to 12 months) and underwent total hip replacement. MRI predictors of positive outcome are lesions with grade A extent, Grade A & B location. Bone marrow oedema with lesions less than 50% involvement, medial and central location. Conclusion Careful selection of patients by MR criteria for core decompression provides satisfactory outcome in precollapse stage of avascular necrosis of hip. PMID:26816966
Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death.
Bernardinelli, Emanuele; Costa, Roberta; Scantamburlo, Giada; To, Janet; Morabito, Rossana; Nofziger, Charity; Doerrier, Carolina; Krumschnabel, Gerhard; Paulmichl, Markus; Dossena, Silvia
2017-01-01
Lipoyl(Octanoyl) Transferase 2 (LIPT2) is a protein involved in the post-translational modification of key energy metabolism enzymes in humans. Defects of lipoic acid synthesis and transfer start to emerge as causes of fatal or severe early-onset disease. We show that the first 31 amino acids of the N-terminus of LIPT2 represent a mitochondrial targeting sequence and inhibition of the transit of LIPT2 to the mitochondrion results in apoptotic cell death associated with activation of the apoptotic volume decrease (AVD) current in normotonic conditions, as well as over-activation of the swelling-activated chloride current (IClswell), mitochondrial membrane potential collapse, caspase-3 cleavage and nuclear DNA fragmentation. The findings presented here may help elucidate the molecular mechanisms underlying derangements of lipoic acid biosynthesis.
Terry, Russell S; Gerke, Travis; Mason, James B; Sorensen, Matthew D; Joseph, Jason P; Dahm, Philipp; Su, Li-Ming
2015-09-01
This study aimed at reviewing a contemporary series of patients who underwent robotic renal and adrenal surgery by a single surgeon at a tertiary referral academic medical center over a 6-year period, specifically focusing on the unique and serious complication of post-operative rhabdomyolysis of the dependent lower extremity. The cases of 315 consecutive patients who underwent robotic upper tract surgery over a 6-year period from August 2008 to June 2014 using a standardized patient positioning were reviewed and analyzed for patient characteristics and surgical variables that may be associated with the development of post-operative rhabdomyolysis. The incidence of post-operative rhabdomyolysis in our series was 3/315 (0.95%). All three affected patients had undergone robotic nephroureterectomy. Those patients who developed rhabdomyolysis had significantly higher mean Body Mass Index, Charlson Comorbidity Index, and median length of stay than those who did not. The mean OR time in the rhabdomyolysis group was noted to be 52 min longer than the non-rhabdomyolysis group, though this value did not reach statistical significance. Given the trends of increasing obesity in the United States and abroad as well as the continued rise in robotic upper tract urologic surgeries, urologists need to be increasingly vigilant for recognizing the risk factors and early treatment of the unique complication of post-operative rhabdomyolysis.
Subramaniam, Dhananjay Radhakrishnan; Mylavarapu, Goutham; McConnell, Keith; Fleck, Robert J; Shott, Sally R; Amin, Raouf S; Gutmark, Ephraim J
2016-05-01
Elasticity of the soft tissues surrounding the upper airway lumen is one of the important factors contributing to upper airway disorders such as snoring and obstructive sleep apnea. The objective of this study is to calculate patient specific elasticity of the pharynx from magnetic resonance (MR) images using a 'tube law', i.e., the relationship between airway cross-sectional area and transmural pressure difference. MR imaging was performed under anesthesia in children with Down syndrome (DS) and obstructive sleep apnea (OSA). An airway segmentation algorithm was employed to evaluate changes in airway cross-sectional area dilated by continuous positive airway pressure (CPAP). A pressure-area relation was used to make localized estimates of airway wall stiffness for each patient. Optimized values of patient specific Young's modulus for tissue in the velopharynx and oropharynx, were estimated from finite element simulations of airway collapse. Patient specific deformation of the airway wall under CPAP was found to exhibit either a non-linear 'hardening' or 'softening' behavior. The localized airway and tissue elasticity were found to increase with increasing severity of OSA. Elasticity based patient phenotyping can potentially assist clinicians in decision making on CPAP and airway or tissue elasticity can supplement well-known clinical measures of OSA severity.
The search for failed supernovae with the Large Binocular Telescope: constraints from 7 yr of data
NASA Astrophysics Data System (ADS)
Adams, S. M.; Kochanek, C. S.; Gerke, J. R.; Stanek, K. Z.
2017-08-01
We report updated results for the first 7 yr of our programme to monitor 27 galaxies within 10 Mpc using the Large Binocular Telescope to search for failed supernovae (SNe) - core collapses of massive stars that form black holes without luminous SNe. In the new data, we identify no new compelling candidates and confirm the existing candidate. Given the six successful core-collapse SNe in the sample and one likely failed SN, the implied fraction of core collapses that result in failed SNe is f=0.14^{+0.33}_{-0.10} at 90 per cent confidence. If the current candidate is a failed SN, the fraction of failed SN naturally explains the missing high-mass red supergiants SN progenitors and the black hole mass function. If the current candidate is ultimately rejected, the data imply a 90 per cent confidence upper limit on the failed SN fraction of f < 0.35.
The importance of an ECG: back to basics.
Haidari, Golaleh; Gray, Kirsty; Kirubakaran, Senthil
2012-11-28
A 48-year-old man presented to accident and emergency with syncope on a background history of 3 weeks of increasing shortness of breath. He collapsed at home prompting admission. He was a smoker with a 30-pack-year history. On examination, he was found to be tachypnoeic and hypoxic, with a raised JVP and quiet heard sounds. He was haemodynamically stable and a chest x-ray showed right upper-lobe collapse. His resting ECG demonstrated electrical alternans prompting urgent referral to the cardiologist for echocardiography. This revealed a large pericardial effusion with evidence of right ventricular diastolic collapse. In view of this, he underwent urgent pericardiocentesis. A subsequent CT scan showed bilateral pleural effusions and multiple lung nodules. Both pericardial and pleural fluid cytology were reported as metastatic non-small cell adenocarcinoma. The pericardial fluid continued to reaccumulate requiring a pericardial window. He was referred to the oncology team for palliative chemotherapy.
Hildebrand, L. R.; Drauch Schreier, Andrea; Lepla, K.; McAdam, S. O.; McLellan, J; Parsley, Michael J.; Paragamian, V L; Young, S P
2016-01-01
White Sturgeon, Acipenser transmontanus (WS), are distributed throughout three major river basins on the West Coast of North America: the Sacramento-San Joaquin, Columbia, and Fraser River drainages. Considered the largest North American freshwater fish, some WS use estuarine habitat and make limited marine movements between river basins. Some populations are listed by the United States or Canada as threatened or endangered (upper Columbia River above Grand Coulee Dam; Kootenai River; lower, middle and, upper Fraser River and Nechako River), while others do not warrant federal listing at this time (Sacramento-San Joaquin Rivers; Columbia River below Grand Coulee Dam; Snake River). Threats that impact WS throughout the species’ range include fishing effects and habitat alteration and degradation. Several populations suffer from recruitment limitations or collapse due to high early life mortality associated with these threats. Efforts to preserve WS populations include annual monitoring, harvest restrictions, habitat restoration, and conservation aquaculture. This paper provides a review of current knowledge on WS life history, ecology, physiology, behavior, and genetics and presents the status of WS in each drainage. Ongoing management and conservation efforts and additional research needs are identified to address present and future risks to the species.
NASA Astrophysics Data System (ADS)
Sun, K.; Cheng, D. B.; He, J. J.; Zhao, Y. L.
2018-02-01
Collapse gully erosion is a specific type of soil erosion in the red soil region of southern China, and early warning and prevention of the occurrence of collapse gully erosion is very important. Based on the idea of risk assessment, this research, taking Guangdong province as an example, adopt the information acquisition analysis and the logistic regression analysis, to discuss the feasibility for collapse gully erosion risk assessment in regional scale, and compare the applicability of the different risk assessment methods. The results show that in the Guangdong province, the risk degree of collapse gully erosion occurrence is high in northeastern and western area, and relatively low in southwestern and central part. The comparing analysis of the different risk assessment methods on collapse gully also indicated that the risk distribution patterns from the different methods were basically consistent. However, the accuracy of risk map from the information acquisition analysis method was slightly better than that from the logistic regression analysis method.
The role of viscosity in TATB hot spot ignition
NASA Astrophysics Data System (ADS)
Fried, Laurence E.; Zepeda-Ruis, Luis; Howard, W. Michael; Najjar, Fady; Reaugh, John E.
2012-03-01
The role of dissipative effects, such as viscosity, in the ignition of high explosive pores is investigated using a coupled chemical, thermal, and hydrodynamic model. Chemical reactions are tracked with the Cheetah thermochemical code coupled to the ALE3D hydrodynamic code. We perform molecular dynamics simulations to determine the viscosity of liquid TATB. We also analyze shock wave experiments to obtain an estimate for the shock viscosity of TATB. Using the lower bound liquid-like viscosities, we find that the pore collapse is hydrodynamic in nature. Using the upper bound viscosity from shock wave experiments, we find that the pore collapse is closest to the viscous limit.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Haniff, S.; Taylor, P. A.
In this paper, we conducted computational macroscale simulations predicting blast-induced intracranial fluid cavitation possibly leading to brain injury. To further understanding of this problem, we developed microscale models investigating the effects of blast-induced cavitation bubble collapse within white matter axonal fiber bundles of the brain. We model fiber tracks of myelinated axons whose diameters are statistically representative of white matter. Nodes of Ranvier are modeled as unmyelinated sections of axon. Extracellular matrix envelops the axon fiber bundle, and gray matter is placed adjacent to the bundle. Cavitation bubbles are initially placed assuming an intracranial wave has already produced them. Pressuremore » pulses, of varied strengths, are applied to the upper boundary of the gray matter and propagate through the model, inducing bubble collapse. Simulations, conducted using the shock wave physics code CTH, predict an increase in pressure and von Mises stress in axons downstream of the bubbles after collapse. This appears to be the result of hydrodynamic jetting produced during bubble collapse. Interestingly, results predict axon cores suffer significantly lower shear stresses from proximal bubble collapse than does their myelin sheathing. Finally, simulations also predict damage to myelin sheathing, which, if true, degrades axonal electrical transmissibility and general health of the white matter structures in the brain.« less
Finn, C A; Sisson, T W; Deszcz-Pan, M
2001-02-01
Hydrothermally altered rocks can weaken volcanoes, increasing the potential for catastrophic sector collapses that can lead to destructive debris flows. Evaluating the hazards associated with such alteration is difficult because alteration has been mapped on few active volcanoes and the distribution and severity of subsurface alteration is largely unknown on any active volcano. At Mount Rainier volcano (Washington, USA), collapses of hydrothermally altered edifice flanks have generated numerous extensive debris flows and future collapses could threaten areas that are now densely populated. Preliminary geological mapping and remote-sensing data indicated that exposed alteration is contained in a dyke-controlled belt trending east-west that passes through the volcano's summit. But here we present helicopter-borne electromagnetic and magnetic data, combined with detailed geological mapping, to show that appreciable thicknesses of mostly buried hydrothermally altered rock lie mainly in the upper west flank of Mount Rainier. We identify this as the likely source for future large debris flows. But as negligible amounts of highly altered rock lie in the volcano's core, this might impede collapse retrogression and so limit the volumes and inundation areas of future debris flows. Our results demonstrate that high-resolution geophysical and geological observations can yield unprecedented views of the three-dimensional distribution of altered rock.
Haniff, S.; Taylor, P. A.
2017-10-17
In this paper, we conducted computational macroscale simulations predicting blast-induced intracranial fluid cavitation possibly leading to brain injury. To further understanding of this problem, we developed microscale models investigating the effects of blast-induced cavitation bubble collapse within white matter axonal fiber bundles of the brain. We model fiber tracks of myelinated axons whose diameters are statistically representative of white matter. Nodes of Ranvier are modeled as unmyelinated sections of axon. Extracellular matrix envelops the axon fiber bundle, and gray matter is placed adjacent to the bundle. Cavitation bubbles are initially placed assuming an intracranial wave has already produced them. Pressuremore » pulses, of varied strengths, are applied to the upper boundary of the gray matter and propagate through the model, inducing bubble collapse. Simulations, conducted using the shock wave physics code CTH, predict an increase in pressure and von Mises stress in axons downstream of the bubbles after collapse. This appears to be the result of hydrodynamic jetting produced during bubble collapse. Interestingly, results predict axon cores suffer significantly lower shear stresses from proximal bubble collapse than does their myelin sheathing. Finally, simulations also predict damage to myelin sheathing, which, if true, degrades axonal electrical transmissibility and general health of the white matter structures in the brain.« less
Aerogeophysical measurements of collapse-prone hydrothermally altered zones at Mount Rainier volcano
Finn, C.A.; Sisson, T.W.; Deszcz-Pan, M.
2001-01-01
Hydrothermally altered rocks can weaken volcanoes, increasing the potential for catastrophic sector collapses that can lead to destructive debris flows1. Evaluating the hazards associated with such alteration is difficult because alteration has been mapped on few active volcanoes1-4 and the distribution and severity of subsurface alteration is largely unknown on any active volcano. At Mount Rainier volcano (Washington, USA), collapses of hydrothermally altered edifice flanks have generated numerous extensive debris flows5,6 and future collapses could threaten areas that are now densely populated7. Preliminary geological mapping and remote-sensing data indicated that exposed alteration is contained in a dyke-controlled belt trending east-west that passes through the volcano's summit3-5,8. But here we present helicopter-borne electromagnetic and magnetic data, combined with detailed geological mapping, to show that appreciable thicknesses of mostly buried hydrothermally altered rock lie mainly in the upper west flank of Mount Rainier. We identify this as the likely source for future large debris flows. But as negligible amounts of highly altered rock lie in the volcano's core, this might impede collapse retrogression and so limit the volumes and inundation areas of future debris flows. Our results demonstrate that high-resolution geophysical and geological observations can yield unprecedented views of the three-dimensional distribution of altered rock.
NASA Astrophysics Data System (ADS)
Haniff, S.; Taylor, P. A.
2017-11-01
We conducted computational macroscale simulations predicting blast-induced intracranial fluid cavitation possibly leading to brain injury. To further understanding of this problem, we developed microscale models investigating the effects of blast-induced cavitation bubble collapse within white matter axonal fiber bundles of the brain. We model fiber tracks of myelinated axons whose diameters are statistically representative of white matter. Nodes of Ranvier are modeled as unmyelinated sections of axon. Extracellular matrix envelops the axon fiber bundle, and gray matter is placed adjacent to the bundle. Cavitation bubbles are initially placed assuming an intracranial wave has already produced them. Pressure pulses, of varied strengths, are applied to the upper boundary of the gray matter and propagate through the model, inducing bubble collapse. Simulations, conducted using the shock wave physics code CTH, predict an increase in pressure and von Mises stress in axons downstream of the bubbles after collapse. This appears to be the result of hydrodynamic jetting produced during bubble collapse. Interestingly, results predict axon cores suffer significantly lower shear stresses from proximal bubble collapse than does their myelin sheathing. Simulations also predict damage to myelin sheathing, which, if true, degrades axonal electrical transmissibility and general health of the white matter structures in the brain.
Gravity or turbulence? IV. Collapsing cores in out-of-virial disguise
NASA Astrophysics Data System (ADS)
Ballesteros-Paredes, Javier; Vázquez-Semadeni, Enrique; Palau, Aina; Klessen, Ralf S.
2018-06-01
We study the dynamical state of massive cores by using a simple analytical model, an observational sample, and numerical simulations of collapsing massive cores. From the analytical model, we find that cores increase their column density and velocity dispersion as they collapse, resulting in a time evolution path in the Larson velocity dispersion-size diagram from large sizes and small velocity dispersions to small sizes and large velocity dispersions, while they tend to equipartition between gravity and kinetic energy. From the observational sample, we find that: (a) cores with substantially different column densities in the sample do not follow a Larson-like linewidth-size relation. Instead, cores with higher column densities tend to be located in the upper-left corner of the Larson velocity dispersion σv, 3D-size R diagram, a result explained in the hierarchical and chaotic collapse scenario. (b) Cores appear to have overvirial values. Finally, our numerical simulations reproduce the behavior predicted by the analytical model and depicted in the observational sample: collapsing cores evolve towards larger velocity dispersions and smaller sizes as they collapse and increase their column density. More importantly, however, they exhibit overvirial states. This apparent excess is due to the assumption that the gravitational energy is given by the energy of an isolated homogeneous sphere. However, such excess disappears when the gravitational energy is correctly calculated from the actual spatial mass distribution. We conclude that the observed energy budget of cores is consistent with their non-thermal motions being driven by their self-gravity and in the process of dynamical collapse.
Gagala, J; Tarczynska, M; Gaweda, K; Matuszewski, L
2014-09-01
Osteonecrosis of the femoral head is an entity which occurs mainly in young and active patients aged between 20 and 50. The success of hip joint preserving treatments ranges from 15% to 50% depending on the stage and amount of osteonecrotic lesion. Total hip replacement is indicated in late post-collapse hips but it has unsatisfactory survival because of the wear and osteolysis in young and active patients. Osteochondral allografts have been reported in the treatment of large articular lesions with defects in underlying bone in knee, talus and shoulder. By combining osteoconductive properties of osteochondral allograft with osteogenic abilities of bone marrow-derived mesenchymal cells it has a potential to be an alternative to an autologous graft. The adjunct of hinged joint distraction should minimize stresses in subchondral bone to promote creeping substitution and prevent femoral head collapse. Unlike current treatment modalities, it would provide both structural support and allow bony and articular substitution. Copyright © 2014 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
John, David A.; Sisson, Thomas W.; Breit, George N.; Rye, Robert O.; Vallance, James W.
2008-08-01
Hydrothermal alteration at Mount Rainier waxed and waned over the 500,000-year episodic growth of the edifice. Hydrothermal minerals and their stable-isotope compositions in samples collected from outcrop and as clasts from Holocene debris-flow deposits identify three distinct hypogene argillic/advanced argillic hydrothermal environments: magmatic-hydrothermal, steam-heated, and magmatic steam (fumarolic), with minor superimposed supergene alteration. The 3.8 km 3 Osceola Mudflow (5600 y BP) and coeval phreatomagmatic F tephra contain the highest temperature and most deeply formed hydrothermal minerals. Relatively deeply formed magmatic-hydrothermal alteration minerals and associations in clasts include quartz (residual silica), quartz-alunite, quartz-topaz, quartz-pyrophyllite, quartz-dickite/kaolinite, and quartz-illite (all with pyrite). Clasts of smectite-pyrite and steam-heated opal-alunite-kaolinite are also common in the Osceola Mudflow. In contrast, the Paradise lahar, formed by collapse of the summit or near-summit of the edifice at about the same time, contains only smectite-pyrite and near-surface steam-heated and fumarolic alteration minerals. Younger debris-flow deposits on the west side of the volcano (Round Pass and distal Electron Mudflows) contain only low-temperature smectite-pyrite assemblages, whereas the proximal Electron Mudflow and a < 100 y BP rock avalanche on Tahoma Glacier also contain magmatic-hydrothermal alteration minerals that are exposed in the avalanche headwall of Sunset Amphitheater, reflecting progressive incision into deeper near-conduit alteration products that formed at higher temperatures. The pre-Osceola Mudflow alteration geometry is inferred to have consisted of a narrow feeder zone of intense magmatic-hydrothermal alteration limited to near the conduit of the volcano, which graded outward to more widely distributed, but weak, smectite-pyrite alteration within 1 km of the edifice axis, developed chiefly in porous breccias. The edifice was capped by a steam-heated alteration zone, most of which resulted from condensation of fumarolic vapor and oxidation of H 2S in the unsaturated zone above the water table. Weakly developed smectite-pyrite alteration extended into the west and east flanks of the edifice, spatially associated with dikes that are localized in those sectors; other edifice flanks lack dikes and associated alteration. The Osceola collapse removed most of the altered core and upper east flank of the volcano, but intensely altered rocks remain on the uppermost west flank. Major conclusions of this study are that: (1) Hydrothermal-mineral assemblages and distributions at Mount Rainier can be understood in the framework of hydrothermal processes and environments developed from studies of ore deposits formed in analogous settings. (2) Frequent eruptions supplied sufficient hot magmatic fluid to alter the upper interior of the volcano hydrothermally, despite the consistently deep (≥ 8 km) magma reservoir which may have precluded formation of economic mineral deposits within or at shallow depths beneath Mount Rainier. The absence of indicator equilibrium alteration-mineral assemblages in the debris flows that effectively expose the volcano to a depth of 1-1.5 km also suggests a low potential for significant high-sulfidation epithermal or porphyry-type mineral deposits at depth. (3) Despite the long and complex history of the volcano, intensely altered collapse-prone rocks were spatially restricted to near the volcano's conduit system and summit, and short distances onto the upper east and west flanks, due to the necessary supply of reactive components carried by ascending magmatic fluids. (4) Intensely altered rocks were removed from the summit, east flank, and edifice interior by the Osceola collapse, but remain on the upper west flank in the Sunset Amphitheater area and present a continuing collapse hazard. (5) Visually conspicuous rocks on the lower east and mid-to-lower west flanks are not intensely altered and probably have not significantly weakened the rock, and thus do not present significant collapse hazards. (6) Alteration developed most intensely within breccia units, because of their high permeability and porosity. Volcanoes with abundant near-conduit upper-edifice breccias are prone to alteration increasing the possibility of collapse, whereas those that are breccia-poor (e.g., massive domes) are less prone to alteration.
Theorising Learning and Nature: Post-Human Possibilities and Problems
ERIC Educational Resources Information Center
Quinn, Jocey
2013-01-01
In their predominantly theoretical turn to the material, post-humanist feminists often focus on "nature", arguing that the nature/culture binary has collapsed and that fixed distinctions between human and non-human spheres no longer hold. Conversely, outdoor learning sees nature as a space where humans act and has been more concerned…
Globalization on the Margins: Education and Post-Socialist Transformations in Central Asia
ERIC Educational Resources Information Center
Silova, Iveta
2010-01-01
The essays in "Globalization on the Margins" explore the continuities and changes in Central Asian education development since the collapse of the Soviet Union in 1991. Reflecting on two decades of post-socialist transformations, they reveal that education systems in Central Asia responded to the rapidly changing political, economic, and…
dos Reis Santos, Israel; Danaga, Aline Roberta; de Carvalho Aguiar, Isabella; Oliveira, Ezequiel Fernandes; Dias, Ismael Souza; Urbano, Jessica Julioti; Martins, Aline Almeida; Ferraz, Leonardo Macario; Fonsêca, Nina Teixeira; Fernandes, Virgilio; Fernandes, Vinicius Alves Thomaz; Lopes, Viviane Cristina Delgado; Leitão Filho, Fernando Sérgio Studart; Nacif, Sérgio Roberto; de Carvalho, Paulo de Tarso Camillo; Sampaio, Luciana Maria Malosá; Giannasi, Lílian Christiane; Romano, Salvatore; Insalaco, Giuseppe; Araujo, Ana Karina Fachini; Dellê, Humberto; Souza, Nadia Karina Guimarães; Giannella-Neto, Daniel; Oliveira, Luis Vicente Franco
2013-10-08
Chronic kidney disease (CKD) is one of the most serious public health problems. The increasing prevalence of CKD in developed and developing countries has led to a global epidemic. The hypothesis proposed is that patients undergoing dialysis would experience a marked negative influence on physiological variables of sleep and autonomic nervous system activity, compromising quality of life. A prospective, consecutive, double blind, randomized controlled clinical trial is proposed to address the effect of dialysis on sleep, pulmonary function, respiratory mechanics, upper airway collapsibility, autonomic nervous activity, depression, anxiety, stress and quality of life in patients with CKD. The measurement protocol will include body weight (kg); height (cm); body mass index calculated as weight/height(2); circumferences (cm) of the neck, waist, and hip; heart and respiratory rates; blood pressures; Mallampati index; tonsil index; heart rate variability; maximum ventilatory pressures; negative expiratory pressure test, and polysomnography (sleep study), as well as the administration of specific questionnaires addressing sleep apnea, excessive daytime sleepiness, depression, anxiety, stress, and quality of life. CKD is a major public health problem worldwide, and its incidence has increased in part by the increased life expectancy and increasing number of cases of diabetes mellitus and hypertension. Sleep disorders are common in patients with renal insufficiency. Our hypothesis is that the weather weight gain due to volume overload observed during interdialytic period will influence the degree of collapsibility of the upper airway due to narrowing and predispose to upper airway occlusion during sleep, and to investigate the negative influences of haemodialysis in the physiological variables of sleep, and autonomic nervous system, and respiratory mechanics and thereby compromise the quality of life of patients. The protocol for this study is registered with the Brazilian Registry of Clinical Trials (ReBEC RBR-7yhr4w and World Health Organization under Universal Trial Number UTN: U1111-1127-9390 [http://www.ensaiosclinicos.gov.br/rg/RBR-7yhr4w/]).
Gravitational collapse and rotation. II - Gravitational radiation and reduction of the a/m ratio
NASA Astrophysics Data System (ADS)
de Felice, F.; Miller, J. C.; Yu, Y.
1985-11-01
During collapse of a nonaxisymmetric rotating ellipsoid, gravitational radiation causes a loss of mass M and angular momentum J. Their combined effect on the behavior of the ratio a/m = cJ/GM2 is investigated for constant density models within a post-Newtonian scheme, and it is found that whenever the value of the ratio is initially greater than 1, it tends toward 1 as the configuration approaches the black hole limit.
The Blue Straggler Star Population in NGC 1261: Evidence for a Post-core-collapse Bounce State
NASA Astrophysics Data System (ADS)
Simunovic, Mirko; Puzia, Thomas H.; Sills, Alison
2014-11-01
We present a multi-passband photometric study of the Blue Straggler Star (BSS) population in the Galactic globular cluster (GC) NGC 1261, using available space- and ground-based survey data. The inner BSS population is found to have two distinct sequences in the color-magnitude diagram (CMD), similar to double BSS sequences detected in other GCs. These well defined sequences are presumably linked to single short-lived events such as core collapse, which are expected to boost the formation of BSSs. In agreement with this, we find a BSS sequence in NGC 1261 which can be well reproduced individually by a theoretical model prediction of a 2 Gyr old population of stellar collision products, which are expected to form in the denser inner regions during short-lived core contraction phases. Additionally, we report the occurrence of a group of BSSs with unusually blue colors in the CMD, which are consistent with a corresponding model of a 200 Myr old population of stellar collision products. The properties of the NGC 1261 BSS populations, including their spatial distributions, suggest an advanced dynamical evolutionary state of the cluster, but the core of this GC does not show the classical signatures of core collapse. We argue that these apparent contradictions provide evidence for a post-core-collapse bounce state seen in dynamical simulations of old GCs.
NASA Astrophysics Data System (ADS)
Borderie, Sandra; Vendeville, Bruno C.; Graveleau, Fabien; Witt, César
2016-04-01
Extension during convergence is a structural process commonly encountered in different geodynamic settings, such as accretionary wedges subjected to tectonic erosion, or mountain belts undergoing post-orogenic collapse. This has been investigated with experimental models at the scale of doubly-vergent wedges (Haq and Davis 2008; Bonini et al. 2000, Buck and Sokoutis 1994) but not thoroughly at the scale of fold-and-thrust belts. During an experimental investigation carried out on the behavior of segmented fold-and-thrust belts induced by stratigraphic inheritance in the foreland series (Borderie et al., EGU this session), unexpected shallow normal faulting occurred. The models comprised one basal frictional décollement (glass microbeads) and one upper viscous décollement embedded in the cover (silicone polymer). Extension took place during the late stages of the experiments and it was localized at the transition zone between the rear domain of the wedge and the frontal fold-and-thrust belt that detached on the upper viscous décollement. Normal faults strike parallel to the compressional structures and mainly dip toward the foreland. They root in the viscous décollement. Through a series of parametrized experiments dedicated to constrain the timing of formation of these extensional structures, we could evidence that these normal faults appear once the bulk shortening in the rear domain has created enough uplift of the internal zone by antiformal stacking and enough forelandward tilting of the upper viscous décollement. These two latter mechanisms are direct consequences of the whole wedge dynamics that links the thrust fault dynamics in the upper shallow sedimentary sequence and the thrust dynamics of the deep subsalt basement. The occurrence of this extension depends on the initial position of the upper viscous décollement and notably the position of the internal pinchout relative to the position of the backstop. Additional tests have also demonstrated that this extension is prevented by surface processes and notably sedimentation. We compare our experimental findings with natural examples of extensional features in various fold-and-thrust belts and accretionary features across the world (e.g. the Mediterranean ridge). References: Bonini, Marco, Dimitrios Sokoutis, Genene Mulugeta, and Emmanouil Katrivanos. 2000. "Modelling Hanging Wall Accommodation above Rigid Thrust Ramps." Journal of Structural Geology 22 (8): 1165-79. Borderie, Sandra, Fabien Graveleau, Cesar Witt and Bruno C. Vendeville. 2016. "Analogue modeling of 3-D structural segmentation in fold-and-thrust belts: interactions between frictional and viscous provinces in foreland basins." Gephys. Res. Abstr., 18, EGU2016-Vienne. Buck, W Roger, and Dimitrios Sokoutis. 1994. "Analogue Model of Gravitational Collapse and Surface Extension during Continental Convergence." Nature 369: 737-40. Haq, Saad SB, and Dan M. Davis. 2008. "Extension during Active Collision in Thin-Skinned Wedges: Insights from Laboratory Experiments." Geology 36 (6): 475-78.
Xiao, Shu-hua; Xue, Jian; Shen, Bing-gui
2010-02-01
To observe the effect of mefloquine on the tegument of adult Schistosoma japonicum harbored in mice. Twelve mice were each infected with 60-80 S. japonicum cercariae. At 35 days post-infection, 10 mice were treated orally with mefloquine at a single dose of 400 mg/kg. Two mice were sacrificed at 8 h, 24 h, 3 days, 7 days, and 14 days post-treatment respectively, and schistosomes were collected by the perfusion technique, fixed and examined under a scanning electron microscope. Schistosomes obtained from the remaining 2 untreated mice served as control. 8 h post-treatment, male and female schistosomes showed focal swelling of the worm body accompanied by extensive swelling, tough junction and fusion of tegumental ridges. Meanwhile, some of the sensory structures showed enlargement and part of them collapsed. 24 h after mefloquine administration, head portion of some male and female worms revealed high swelling accompanied by severe damage to oral sucker. 3 days post-treatment, focal swelling of worm body along the whole worm was universal. In some male and female worms, the damaged tegument fused together to form a large mass protruding from the tegumental surface. In addition, focal or extensive peeling of tegumental ridges was seen or collapse of enlarged sensory structure resulted in formation of hole-like appearance. 7 days post administration, focal swelling of worm body and damage to tegument induced by mefloquine were similar to those aforementioned, but focal peeling, collapse of enlarged sensory structures, and deformation of oral sucker in male and female worms were universal. 14 days post-treatment, individual male worm survived the treatment revealed normal appearance of tegumental ridges in head portion, although light focal swelling of worm body was still observed. Mefloquine causes focal swelling of worm body, extensive and severe damage to the tegument in adult S. japonicum.
Glacier Acceleration and Thinning after Ice Shelf Collapse in the Larsen B Embayment, Antarctica
NASA Technical Reports Server (NTRS)
Scambos, T. A.; Bohlander, J. A.; Shuman, C. A.; Skvarca, P.
2004-01-01
Ice velocities derived from five Landsat 7 images acquired between January 2000 and February 2003 show a two- to six-fold increase in centerline speed of four glaciers flowing into the now-collapsed section of the Larsen B Ice Shelf. Satellite laser altimetry from ICEsat indicates the surface of Hektoria Glacier lowered by up to 38 +/- 6 m a six-month period beginning one year after the break-up in March 2002. Smaller elevation losses are observed for Crane and Jorum glaciers over a later 5-month period. Two glaciers south of the collapse area, Flask and Leppard, show little change in speed or elevation. Seasonal variations in speed preceding the large post-collapse velocity increases suggest that both summer melt percolation and changes in the stress field due to shelf removal play a major role in glacier dynamics.
Collapse risk of buildings in the Pacific Northwest region due to subduction earthquakes
Raghunandan, Meera; Liel, Abbie B.; Luco, Nicolas
2015-01-01
Subduction earthquakes similar to the 2011 Japan and 2010 Chile events will occur in the future in the Cascadia subduction zone in the Pacific Northwest. In this paper, nonlinear dynamic analyses are carried out on 24 buildings designed according to outdated and modern building codes for the cities of Seattle, Washington, and Portland, Oregon. The results indicate that the median collapse capacity of the ductile (post-1970) buildings is approximately 40% less when subjected to ground motions from subduction, as compared to crustal earthquakes. Buildings are more susceptible to earthquake-induced collapse when shaken by subduction records (as compared to crustal records of the same intensity) because the subduction motions tend to be longer in duration due to their larger magnitude and the greater source-to-site distance. As a result, subduction earthquakes are shown to contribute to the majority of the collapse risk of the buildings analyzed.
Meinhardt, J P; Ashton, B A; Annich, G M; Quintel, M; Hirschl, R B
2003-05-30
To evaluate the influence of pump system and flow pattern on expiratory airway collapse (EAC) in total perfluorocarbon ventilation. - Prospective, controlled, randomized animal trial for determination of (1) post-mortem changes by repeated expiration procedures (EP) with a constant flow piston pump (PP) before and after sacrifice (n = 8 rabbits), (2) differences between pump systems by subjecting animals to both PP and roller pump (RP) circuits for expiration (n = 16 rabbits). EP were performed using a servo-controlled shut-off at airway pressures < 25 cm H subset 2O randomly with either pump at different flows. - Expired volumes before and after sacrifice were not significantly different. PP and RP revealed identical mean flows, while significantly more liquid was drained using PP (p<0.05). Increasing differences towards higher flow rates indicated profound flow pulsatility in RP. - (1) post-mortem changes in expired volumes are not significant, (2) EAC is related to flow rate and pump system; (3) relationship between expiratory flow rate and drainable liquid volume is linear inverse; (4) PP provides higher drainage than RP. - Expiratory airway collapse is related to flow rate and pump system, post mortem changes in expirable volumes are not significant. Relationship between expiratory flow rate and drainable liquid volume is linear inverse, piston pump expiration provides higher drainage volumes than roller pump expiration.
NASA Astrophysics Data System (ADS)
Ramzi, Azizi; Lassaad, Chihi
2017-09-01
New field observations carried out in northeastern Tunisia (Kechabta Neogene basin) allowed us to clarify and pinpoint the chronology of the folding phases which had been the subject of contradictions in previous studies. To better understand the folding in the study area, a set of structural, lithostratigraphic and cartographic arguments are given in order to confirm the Atlassic folding phase (upper Tortonian) affecting rheologically weak and incompetent materials of the Neogene layers. In the Kechabta Neogene basin, the upper Tortonian folding is materialized by an unconformity between the Kechabta (Tortonian) and the Oued Bel Khedim (Messinian) formations. The highlight of this event allows us to identify the current fold structure of the study area as a superposition of two major folding episodes: The first one occurred during the upper Tortonian, and the second in the Early Quaternary (post-Villafranchian). The chronological consistency of the upper Tortonian folding in the Kechabta basin with the rest of the Tunisian chains allows for a better understanding of the collision context (Miocene to the Quaternary) which dominated the western Mediterranean Sea and steered the structural evolution of Tunisia.
Marsh collapse thresholds for coastal Louisiana estimated using elevation and vegetation index data
Couvillion, Brady R.; Beck, Holly
2013-01-01
Forecasting marsh collapse in coastal Louisiana as a result of changes in sea-level rise, subsidence, and accretion deficits necessitates an understanding of thresholds beyond which inundation stress impedes marsh survival. The variability in thresholds at which different marsh types cease to occur (i.e., marsh collapse) is not well understood. We utilized remotely sensed imagery, field data, and elevation data to help gain insight into the relationships between vegetation health and inundation. A Normalized Difference Vegetation Index (NDVI) dataset was calculated using remotely sensed data at peak biomass (August) and used as a proxy for vegetation health and productivity. Statistics were calculated for NDVI values by marsh type for intermediate, brackish, and saline marsh in coastal Louisiana. Marsh-type specific NDVI values of 1.5 and 2 standard deviations below the mean were used as upper and lower limits to identify conditions indicative of collapse. As marshes seldom occur beyond these values, they are believed to represent a range within which marsh collapse is likely to occur. Inundation depth was selected as the primary candidate for evaluation of marsh collapse thresholds. Elevation relative to mean water level (MWL) was calculated by subtracting MWL from an elevation dataset compiled from multiple data types including light detection and ranging (lidar) and bathymetry. A polynomial cubic regression was used to examine a random subset of pixels to determine the relationship between elevation (relative to MWL) and NDVI. The marsh collapse uncertainty range values were found by locating the intercept of the regression line with the 1.5 and 2 standard deviations below the mean NDVI value for each marsh type. Results indicate marsh collapse uncertainty ranges of 30.7–35.8 cm below MWL for intermediate marsh, 20–25.6 cm below MWL for brackish marsh, and 16.9–23.5 cm below MWL for saline marsh. These values are thought to represent the ranges of inundation depths within which marsh collapse is probable.
Fishing amplifies forage fish population collapses.
Essington, Timothy E; Moriarty, Pamela E; Froehlich, Halley E; Hodgson, Emma E; Koehn, Laura E; Oken, Kiva L; Siple, Margaret C; Stawitz, Christine C
2015-05-26
Forage fish support the largest fisheries in the world but also play key roles in marine food webs by transferring energy from plankton to upper trophic-level predators, such as large fish, seabirds, and marine mammals. Fishing can, thereby, have far reaching consequences on marine food webs unless safeguards are in place to avoid depleting forage fish to dangerously low levels, where dependent predators are most vulnerable. However, disentangling the contributions of fishing vs. natural processes on population dynamics has been difficult because of the sensitivity of these stocks to environmental conditions. Here, we overcome this difficulty by collating population time series for forage fish populations that account for nearly two-thirds of global catch of forage fish to identify the fingerprint of fisheries on their population dynamics. Forage fish population collapses shared a set of common and unique characteristics: high fishing pressure for several years before collapse, a sharp drop in natural population productivity, and a lagged response to reduce fishing pressure. Lagged response to natural productivity declines can sharply amplify the magnitude of naturally occurring population fluctuations. Finally, we show that the magnitude and frequency of collapses are greater than expected from natural productivity characteristics and therefore, likely attributed to fishing. The durations of collapses, however, were not different from those expected based on natural productivity shifts. A risk-based management scheme that reduces fishing when populations become scarce would protect forage fish and their predators from collapse with little effect on long-term average catches.
Niles, Justin K; Webber, Mayris P; Liu, Xiaoxue; Zeig-Owens, Rachel; Hall, Charles B; Cohen, Hillel W; Glaser, Michelle S; Weakley, Jessica; Schwartz, Theresa M; Weiden, Michael D; Nolan, Anna; Aldrich, Thomas K; Glass, Lara; Kelly, Kerry J; Prezant, David J
2014-08-01
We investigated early post 9/11 factors that could predict rhinosinusitis healthcare utilization costs up to 11 years later in 8,079 World Trade Center-exposed rescue/recovery workers. We used bivariate and multivariate analytic techniques to investigate utilization outcomes; we also used a pyramid framework to describe rhinosinusitis healthcare groups at early (by 9/11/2005) and late (by 9/11/2012) time points. Multivariate models showed that pre-9/11/2005 chronic rhinosinusitis diagnoses and nasal symptoms predicted final year healthcare utilization outcomes more than a decade after WTC exposure. The relative proportion of workers on each pyramid level changed significantly during the study period. Diagnoses of chronic rhinosinusitis within 4 years of a major inhalation event only partially explain future healthcare utilization. Exposure intensity, early symptoms and other factors must also be considered when anticipating future healthcare needs. © 2014 Wiley Periodicals, Inc.
Niles, Justin K.; Webber, Mayris P.; Liu, Xiaoxue; Zeig-Owens, Rachel; Hall, Charles B.; Cohen, Hillel W.; Glaser, Michelle S.; Weakley, Jessica; Schwartz, Theresa M.; Weiden, Michael D.; Nolan, Anna; Aldrich, Thomas K.; Glass, Lara; Kelly, Kerry J.; Prezant, David J.
2015-01-01
Background We investigated early post 9/11 factors that could predict rhinosinusitis healthcare utilization costs up to 11 years later in 8,079 World Trade Center-exposed rescue/recovery workers. Methods We used bivariate and multivariate analytic techniques to investigate utilization outcomes; we also used a pyramid framework to describe rhinosinusitis healthcare groups at early (by 9/11/2005) and late (by 9/11/2012) time points. Results Multivariate models showed that pre-9/11/2005 chronic rhinosinusitis diagnoses and nasal symptoms predicted final year healthcare utilization outcomes more than a decade after WTC exposure. The relative proportion of workers on each pyramid level changed significantly during the study period. Conclusions Diagnoses of chronic rhinosinusitis within 4 years of a major inhalation event only partially explain future healthcare utilization. Exposure intensity, early symptoms and other factors must also be considered when anticipating future healthcare needs. PMID:24898816
Tectonic Evolution of the Çayirhan Neogene Basin (Ankara), Central Turkey
NASA Astrophysics Data System (ADS)
Behzad, Bezhan; Koral, Hayrettin; İşb&idot; l, Duygu; Karaaǧa; ç, Serdal
2016-04-01
Çayırhan (Ankara) is located at crossroads of the Western Anatolian extensional region, analogous to the Basin and Range Province, and suture zone of the Neotethys-Ocean, which is locus of the North Anatolian Transform since the Late Miocene. To the north of Çayırhan (Ankara), a Neogene sedimentary basin comprises Lower-Middle Miocene and Upper Miocene age formations, characterized by swamp, fluvial and lacustrine settings respectively. This sequence is folded and transected by neotectonic faults. The Sekli thrust fault is older than the Lower-Middle Miocene age formations. The Davutoǧlan fault is younger than the Lower-Middle Miocene formations and is contemporaneous to the Upper Miocene formation. The Çatalkaya fault is younger than the Upper Miocene formation. The sedimentary and tectonic features provide information on mode, timing and evolution of this Neogene age sedimentary basin in Central Turkey. It is concluded that the region underwent a period of uplift and erosion under the influence of contractional tectonics prior to the Early-Middle Miocene, before becoming a semi-closed basin under influence of transtensional tectonics during the Early-Middle Miocene and under influence of predominantly extensional tectonics during the post-Late Miocene times. Keywords: Tectonics, Extension, Transtension, Stratigraphy, Neotectonic features.
Bower, Kelly J; Clark, Ross A; McGinley, Jennifer L; Martin, Clarissa L; Miller, Kimberly J
2014-09-01
To investigate the feasibility and potential efficacy of the Nintendo Wii™ for balance rehabilitation after stroke. Phase II, single-blind, randomized controlled trial. Inpatient rehabilitation facility. Thirty adults (mean age 63.6 (14.7) years) undergoing inpatient rehabilitation who were less than three months post-stroke and able to stand unsupported. Participants were allocated to a Balance Group, using the 'Wii Fit Plus' in standing, or Upper Limb Group, using the 'Wii Sports/Sports Resort' in sitting. Both groups undertook three 45 minute sessions per week over two to four weeks in addition to standard care. The primary focus was feasibility, addressed by recruitment, retention, adherence, acceptability and safety. Efficacy was evaluated by balance, mobility and upper limb outcomes. Twenty-one percent of individuals screened were recruited and 86% (n = 30) of eligible people agreed to participate. Study retention and session adherence was 90% and > 99%, respectively, at two weeks; dropping to 70% and 87% at four weeks due to early discharge. All participants reported enjoying the sessions and most felt they were beneficial. No major adverse events occurred. Wii use by the Balance Group was associated with trends for improved balance, with significantly greater improvement in outcomes including the Step Test and Wii Balance Board-derived centre of pressure scores. The Upper Limb Group had larger, non-significant changes in arm function. A Wii-based approach appears feasible and promising for post-stroke balance rehabilitation. A larger randomized controlled trial is recommended to further investigate efficacy. © The Author(s) 2014.
Exercise prescription after fragility fracture in older adults: a scoping review
Feehan, Lynne M.; Beck, Charlotte A.; Harris, Susan R.; MacIntyre, Donna L.; Li, Linda C.
2017-01-01
Purpose To identify and chart research literature on safety, efficacy or effectiveness of exercise prescription following fracture in older adults. Methods We conducted a systematic, research-user-informed, scoping review. The population of interest was adults aged ≥ 45 years with any fracture. ‘Exercise prescription’ included post-fracture therapeutic exercise, physical activity or rehabilitation interventions. Eligible designs included knowledge synthesis studies, primary interventional studies and observational studies. Trained reviewers independently evaluated citations for inclusion. Results A total of 9415 citations were reviewed with 134 citations (119 unique studies) identified: 13 knowledge syntheses, 95 randomized or controlled clinical trials, and 11 ‘other’ designs, representing 74 articles on lower extremity fractures, 34 on upper extremity, eight on vertebral, and three on mixed body region fractures. Exercise prescription characteristics were often missing or poorly described. Six general categories emerged describing exercise prescription characteristics: timing post-fracture, person prescribing, program design, functional focus, exercise script parameters and co-interventions. Upper extremity and ankle fracture studies focused on fracture healing or structural impairment outcomes, whereas hip fracture studies focused more on activity limitation outcomes. The variety of different outcome measures used made pooling or comparison of outcomes difficult. Conclusions There was insufficient information to identify evidence-informed parameters for safe and effective exercise prescription for older adults following fracture. Key gaps in the literature include limited numbers of studies on exercise prescription following vertebral fracture, poor delineation of effectiveness of different strategies for early post-fracture mobilization following upper extremity fracture, and inconsistent details of exercise prescription characteristics after lower extremity fracture. PMID:20967425
Constraints on lateral variations in upper mantle viscosity from Lake Bonneville shorelines
NASA Astrophysics Data System (ADS)
Austermann, Jacqueline; Chen, Christine; Lau, Harriet C. P.
2017-04-01
Lake Bonneville is an extinct pluvial lake that formed and catastrophically drained at the onset of the last deglaciation (˜ 20 - 18ka). With a volume of just over 10 000 km3 this lake was comparable in size to present-day Lake Michigan. During its existence the excess load of water stored in Lake Bonneville depressed the crust and upper mantle. After the drainage of the lake this area rebounded by up to 75 m, which is recorded in the paleoshorelines around the lake periphery and on islands within the lake. The rebound pattern has been used to infer the lithospheric thickness and upper mantle viscosity structure of the area (e.g. Bill et al., 1994). In agreement with the tectonic history of the Basin and Range area, the deformed shorelines point to a thin lithosphere (< 30km) and low upper mantle viscosity (˜ 1019 Pa s). This differs from the upper mantle viscosity inferred from post-glacial data in cratonic regions (e.g., Hudson Bay, Fennoscandia), which is one to two orders of magnitude larger (˜ 5 × 1020 Pa s). Direct constraints on the lateral variability of mantle viscosity are invaluable but in order to utilize such constraints it is important to consider the sensitivity range of different observations before comparing the inferred viscosities. In this study we revisit the earlier inversions of shoreline elevations for mantle and lithospheric structure with an updated dataset of paleoshoreline elevations by Chen and Maloof (2017). We construct depth-dependent sensitivity kernels for the lake rebound and compare them to kernels associated with the rebound from glacial ice sheets over Canada and Scandinavia. This comparison along with the inferred viscosities allows us to evaluate the degree to which lateral viscosity variations are required. We additionally compare our results to estimates of lateral viscosity variations based on perturbations in seismic shear wave speed in the respective areas in order to assess the consistency of our results with independent data. The paleoshorelines of Lake Bonneville have been deflected by not only rebound post-drainage, but also the longer-term subsidence of the Laurentide peripheral bulge. The lake was located on the distal flank of the peripheral bulge of the Laurentide Ice Sheet and after its collapse the peripheral bulge subsided leading to an additional northeast trending tilt in shoreline elevations. We show that the degree of tilt is not only sensitive to shallow mantle structure but has also sensitivity in the upper half of the lower mantle, in contrast to the lake rebound pattern. We independently invert the degree of tilt for mantle viscosity and examine its trade-off with uncertainties in the ice history.
Post-1500 Population Flows and the Long Run Determinants of Economic Growth and Inequality
Putterman, Louis; Weil, David N.
2013-01-01
We construct a matrix showing the share of the year 2000 population in every country that is descended from people in different source countries in the year 1500. Using the matrix to adjust indicators of early development so they reflect the history of a population’s ancestors rather than the history of the place they live today greatly improves the ability of those indicators to predict current GDP. The variance of early development history of a country’s inhabitants is a good predictor for current inequality, with ethnic groups originating in regions having longer histories of organized states tending to be at the upper end of a country’s income distribution. PMID:24478530
Post-1500 Population Flows and the Long Run Determinants of Economic Growth and Inequality.
Putterman, Louis; Weil, David N
2010-01-01
We construct a matrix showing the share of the year 2000 population in every country that is descended from people in different source countries in the year 1500. Using the matrix to adjust indicators of early development so they reflect the history of a population's ancestors rather than the history of the place they live today greatly improves the ability of those indicators to predict current GDP. The variance of early development history of a country's inhabitants is a good predictor for current inequality, with ethnic groups originating in regions having longer histories of organized states tending to be at the upper end of a country's income distribution.
Supersonic gas streams enhance the formation of massive black holes in the early universe.
Hirano, Shingo; Hosokawa, Takashi; Yoshida, Naoki; Kuiper, Rolf
2017-09-29
The origin of super-massive black holes in the early universe remains poorly understood. Gravitational collapse of a massive primordial gas cloud is a promising initial process, but theoretical studies have difficulty growing the black hole fast enough. We report numerical simulations of early black hole formation starting from realistic cosmological conditions. Supersonic gas motions left over from the Big Bang prevent early gas cloud formation until rapid gas condensation is triggered in a protogalactic halo. A protostar is formed in the dense, turbulent gas cloud, and it grows by sporadic mass accretion until it acquires 34,000 solar masses. The massive star ends its life with a catastrophic collapse to leave a black hole-a promising seed for the formation of a monstrous black hole. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
The Consequences of Increased Magma Supply to Kilauea Volcano, Hawai`i
NASA Astrophysics Data System (ADS)
Poland, M.; Miklius, A.; Sutton, A. J.; Orr, T.
2007-12-01
The summer of 2007 was a time of intense activity at Kilauea. By mid-2007, ~4 years of summit inflation had uplifted and extended the caldera by 30 cm and 55 cm, respectively. Lava continued to erupt from the Pu`u `O`o vent on the east rift zone (ERZ) during the inflation. On May 24, 2007, two M4+ normal-faulting earthquakes occurred on caldera-bounding faults southeast of the summit. The seismicity did not affect summit inflation, which continued until June 17 when a dike intruded the upper and middle ERZ, causing a pause in the eruption, collapse of Pu`u `O`o's floor, and a small eruption 6 km uprift of Pu`u `O`o. The inflated state of the summit, relative timing of summit deflation and east rift zone extension, and abundant co-intrusive earthquake activity suggest forcible intrusion of magma. Lava returned to Pu`u `O`o by July 2, forming a lake that gradually refilled much of the collapsed crater. Early on July 21, the lake drained suddenly, the cone began to collapse, and a 2-km-long series of discontinuous eruptive fissures opened on and beyond the east flank of Pu`u `O`o. Sesimicity in Kilauea's south flank has been elevated since June and several M3+ earthquakes have occurred there, including a M5.4 on August 13. An increase in magma supply to Kilauea's shallow magmatic system is the probable cause for the events of summer 2007. Summit inflation since 2003 occurred during a period of constant or increasing magma supply to Pu`u `O`o, based on SO2 emissions from the ERZ. The rate of inflation increased markedly in early 2006, and uplift also began in the southwest rift zone. CO2 emissions at the summit, indicative of the quantity of magma degassing beneath Kilauea's caldera, more than doubled between 2003 and 2006. Also since 2003, the ERZ immediately downrift of Pu`u `O`o extended, and subsidence in the lower ERZ ceased. Together, these factors suggest that the magma supply rate to Kilauea's shallow magmatic system (the summit and rift zones above about 5 km depth) approximately doubled between 2003 and 2006. Subsequent volcanic and earthquake activity, including the events of mid-2007, are probably a result (either directly or indirectly) of this increase.
Chakrabarti, Nikhil; Maity, Chandan; Schamel, Hans
2011-04-08
Compressional waves in a magnetized plasma of arbitrary resistivity are treated with the lagrangian fluid approach. An exact nonlinear solution with a nontrivial space and time dependence is obtained with boundary conditions as in Harris' current sheet. The solution shows competition among hydrodynamic convection, magnetic field diffusion, and dispersion. This results in a collapse of density and the magnetic field in the absence of dispersion. The dispersion effects arrest the collapse of density but not of the magnetic field. A possible application is in the early stage of magnetic star formation.
Early stages of collapsing pentacene crystal by Au
NASA Astrophysics Data System (ADS)
Ihm, Kyuwook; Chung, Sukmin; Kang, Tai-Hee; Cheong, Sang-Wook
2008-10-01
The characteristic feature of metal contacts with gold on organics is deterioration of the organic crystals during the contact formation. The unveiled key challenge is to probe dynamic details of the microscopic evolution of the organic crystal when the atomic Au is introduced. Here, we report how the collapse of the pentacene crystal is initiated even by a few Au atoms. Our results indicate that the gentle decoupling of intra and intermolecular π-π interactions causes the localization of the lowest unoccupied molecular orbital as well as the removal of cohesive forces between molecules, leading to the subsequent crystal collapse.
Early warning signals detect critical impacts of experimental warming.
Jarvis, Lauren; McCann, Kevin; Tunney, Tyler; Gellner, Gabriel; Fryxell, John M
2016-09-01
Earth's surface temperatures are projected to increase by ~1-4°C over the next century, threatening the future of global biodiversity and ecosystem stability. While this has fueled major progress in the field of physiological trait responses to warming, it is currently unclear whether routine population monitoring data can be used to predict temperature-induced population collapse. Here, we integrate trait performance theory with that of critical tipping points to test whether early warning signals can be reliably used to anticipate thermally induced extinction events. We find that a model parameterized by experimental growth rates exhibits critical slowing down in the vicinity of an experimentally tested critical threshold, suggesting that dynamical early warning signals may be useful in detecting the potentially precipitous onset of population collapse due to global climate change.
Spatial biostratigraphy of NW Pakistan
NASA Astrophysics Data System (ADS)
Shafique, Naseer Ahmed
2001-07-01
Mesozoic to Cenozoic biostratigraphy of NW Pakistan has been conducted in order to document the temporal and spatial relationship between different marine strata with the help of remote sensing and Geographic Information Systems (GIS). These relationships were then used to help distinguish different tectonostratigraphic units in the Waziristan and the Kurram areas located at the northwestern margin of the Indo-Pakistani craton. Extensive biostratigraphic work in the Waziristan and Kurram areas enabled to distinguish five tectonostratigraphic units and two significant unconformities in the study area. Different foraminiferal zones from Early Jurassic to Middle Eocenewere developed, although due to random samples these zones are not continuous in the sedimentary record. However continuous biozonation from the Late Paleocene P4 to the Early Eocene P9 (Bolli, 1985) biozone was observed. It is observed that the Santonian stage is generally missing in the sedimentary sequence, and it is only found in the olistoliths. This implies that during the Campanian stage there was instability in the shelf due to ophiolite obduction, which caused the displacement of the Santonian strata. The absence of Early Paleocene (Zone P1--P3) microfauna is suggested by rapid subsidence of the NW Indian shelf beginning in the early Paleocene. Moreover, index fossils for the Palpha, P1a, b, c, d, P2 and P3 biozones are absent in the melange of the Thal area suggesting regional uplift during the Paleocene. The presence of Planorotalites pseudomenardii P4 zone microfauna above the unconformable Upper Cretaceous Kahi melange strata suggest the India-Asia collision age between 58 Ma--56 Ma. Foraminiferal biostratigraphy of upper Cretaceous olistoliths was conducted from the Mughal Kot gorge, Baluchistan, Pakistan in order to reveal the depositional history of Late Santonian aged (Dicarinella asymmetrica zone) olistoliths and associated upper Cretaceous to early Tertiary Indo-Pakistani shelf strata. These olistoliths are embedded in uppermost Campanian strata of the Mughal Kot Formation. Similar olistostromes are found at approximately the same stratigraphic level across a broad region of NW Pakistan. These olistostromes are similar in age to radiometrically constrained deformation in the Zhob and Waziristan ophiolites 50 and 90 km to the west and northwest respectively and may record incipient underthrusting of the NW Indo Pakistani craton beneath oceanic crust now in Waziristan and northern Baluchistan. This Campanian event precedes stratigraphically constrained Paleocene and Early Eocene deformation in Parachinar, Orakzai and the Attock-Cherat Ranges, which is interpreted as the collision of NW Indo-Pakistan with Asia and the Kabul Block. A turbiditic depositional environment of the Mughal Kot Formation was developed due to the regional collapse of the NW Indo-Pakistani shelf margin during the Late Campanian (G. calcarata zone ˜80--74 Ma), possibly as a result of ophiolite obduction as the Indo-Pakistani plate moved beneath Tethyan oceanic crust.
Faith and Reason in a Post Secular Age
ERIC Educational Resources Information Center
Radford, Mike
2012-01-01
The problems that this article seeks to address are those that are raised in the context of the bilateralism that is established when we think in terms of secularism as primarily orientated towards reason and post secularism, towards faith. The objective of the article is to show that the distinction between the two can be collapsed. Post…
2013-10-01
requiring pacemaker Refusal of consent - Claustrophobia Spinal Cord Injury Unstable due to tracheal stenosis and lobar collapse 2 patients had...be stopped. Heart Block necessitating pacemaker Unstable from a respiratory point of view due to previous Left lower lobectomy, right upper
4. LOWER NOTTINGHAM MINE. DETAIL OF OBJECTS ASSOCIATED WITH CABIN ...
4. LOWER NOTTINGHAM MINE. DETAIL OF OBJECTS ASSOCIATED WITH CABIN 'B'; PIPE, WOOD, STOVE MATERIALS, AND COLLAPSED ROOT CELLAR IN CENTRAL AREA. VERTICAL, DARK PIPE IS VISIBLE IN CENTER/UPPER THIRD. CAMERA POINTED EAST. - Florida Mountain Mining Sites, Lower Nottingham Mine, Western slope of Florida Mountain, Silver City, Owyhee County, ID
NASA Astrophysics Data System (ADS)
1984-12-01
Surface landforms in the Salt Valley Area are generally a function of the Salt Valley anticline and are characterized by parallel and subparallel cuestaform ridges and hogbacks and flat valley floors. The most prominent structure in the Area is the Salt Valley anticline. Erosion resulting from the Tertiary uplift of the Colorado Plateau led to salt dissolution and subsequent collapse along the crest of the anticline. Continued erosion removed the collapse material, forming an axial valley along the crest of the anticline. Paleozoic rocks beneath the salt bearing Paradox Formation consist of limestone, dolomite, sandstone, siltstone and shale. The salt beds of the Paradox formation occur in distinct cycles separated by an interbed sequence of anhydrite, carbonate, and clastic rocks. The Paradox Formation is overlain by Pennsylvanian limestone; Permian sandstone; and Mesozoic sandstone, mudstone, conglomerate and shale. No earthquakes have been reported in the area during the period of the historic record and contemporary seismicity appears to be diffusely distributed, of low level and small magnitude. The upper unit includes the Permian strata and upper Honaker trail formation.
COSMIC-LAB: Double BSS sequences as signatures of the Core Collapse phenomenon in star clusters.
NASA Astrophysics Data System (ADS)
Ferraro, Francesco
2011-10-01
Globular Clusters {GCs} are old stellar systems tracing key stages of the star formation and chemical enrichment history of the early Universe and the galaxy assembly phase. As part of a project {COSMIC-LAB} aimed at using GCs as natural laboratories to study the complex interplay between dynamics and stellar evolution, here we present a proposal dealing with the role of Blue Straggler Stars {BSS}.BSS are core-hydrogen burning stars more massive than the main-sequence turnoff population. The canonical scenarios for BSS formation are either the mass transfer between binary companions, or stellar mergers induced by collisions. We have recently discovered two distinct and parallel sequences of BSS in the core of M30 {Ferraro et al. 2009, Nature 462, 1082}. We suggested that each of the two sequences is populated by BSS formed by one of the two processes, both triggered by the cluster core collapse, that, based on the observed BSS properties, must have occurred 1-2 Gyr ago. Following this scenario, we have identified a powerful "clock" to date the occurrence of this key event in the GC history.Here we propose to secure WFC3 images of 4 post-core collapse GCs, reaching S/N=200 at the BSS magnitude level, in order to determine the ubiquity of the BSS double sequence and calibrate the "dynamical clock". This requires very high spatial resolution and very high precision photometry capabilities that are unique to the HST. The modest amount of requested time will have a deep impact on the current and future generations of dynamical evolutionary models of collisional stellar systems.
Numerosity processing in early visual cortex.
Fornaciai, Michele; Brannon, Elizabeth M; Woldorff, Marty G; Park, Joonkoo
2017-08-15
While parietal cortex is thought to be critical for representing numerical magnitudes, we recently reported an event-related potential (ERP) study demonstrating selective neural sensitivity to numerosity over midline occipital sites very early in the time course, suggesting the involvement of early visual cortex in numerosity processing. However, which specific brain area underlies such early activation is not known. Here, we tested whether numerosity-sensitive neural signatures arise specifically from the initial stages of visual cortex, aiming to localize the generator of these signals by taking advantage of the distinctive folding pattern of early occipital cortices around the calcarine sulcus, which predicts an inversion of polarity of ERPs arising from these areas when stimuli are presented in the upper versus lower visual field. Dot arrays, including 8-32dots constructed systematically across various numerical and non-numerical visual attributes, were presented randomly in either the upper or lower visual hemifields. Our results show that neural responses at about 90ms post-stimulus were robustly sensitive to numerosity. Moreover, the peculiar pattern of polarity inversion of numerosity-sensitive activity at this stage suggested its generation primarily in V2 and V3. In contrast, numerosity-sensitive ERP activity at occipito-parietal channels later in the time course (210-230ms) did not show polarity inversion, indicating a subsequent processing stage in the dorsal stream. Overall, these results demonstrate that numerosity processing begins in one of the earliest stages of the cortical visual stream. Copyright © 2017 Elsevier Inc. All rights reserved.
The Role of Viscosity in TATB Hot Spot Ignition
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fried, L E; Zepeda-Ruis, L; Howard, W M
2011-08-02
The role of dissipative effects, such as viscosity, in the ignition of high explosive pores is investigated using a coupled chemical, thermal, and hydrodynamic model. Chemical reactions are tracked with the Cheetah thermochemical code coupled to the ALE3D hydrodynamic code. We perform molecular dynamics simulations to determine the viscosity of liquid TATB. We also analyze shock wave experiments to obtain an estimate for the shock viscosity of TATB. Using the lower bound liquid-like viscosities, we find that the pore collapse is hydrodynamic in nature. Using the upper bound viscosity from shock wave experiments, we find that the pore collapse ismore » closest to the viscous limit.« less
NASA Astrophysics Data System (ADS)
Torres-Forné, Alejandro; Cerdá-Durán, Pablo; Passamonti, Andrea; Font, José A.
2018-03-01
Gravitational waves from core-collapse supernovae are produced by the excitation of different oscillation modes in the protoneutron star (PNS) and its surroundings, including the shock. In this work we study the relationship between the post-bounce oscillation spectrum of the PNS-shock system and the characteristic frequencies observed in gravitational-wave signals from core-collapse simulations. This is a fundamental first step in order to develop a procedure to infer astrophysical parameters of the PNS formed in core-collapse supernovae. Our method combines information from the oscillation spectrum of the PNS, obtained through linear perturbation analysis in general relativity of a background physical system, with information from the gravitational-wave spectrum of the corresponding non-linear, core-collapse simulation. Using results from the simulation of the collapse of a 35 M⊙ pre-supernova progenitor we show that both types of spectra are indeed related and we are able to identify the modes of oscillation of the PNS, namely g-modes, p-modes, hybrid modes, and standing accretion shock instability (SASI) modes, obtaining a remarkably close correspondence with the time-frequency distribution of the gravitational-wave modes. The analysis presented in this paper provides a proof of concept that asteroseismology is indeed possible in the core-collapse scenario, and it may serve as a basis for future work on PNS parameter inference based on gravitational-wave observations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Famiano, M. A.; Kajino, T.; Aoki, W.
A model is proposed in which the dependence on the equation of state (EOS) of the scatter of [Sr/Ba] in metal-poor stars is studied. Light r-process element enrichment in these stars has been explained via a truncated r-process, or “tr-process.” The truncation of the r-process from a generic core-collapse event followed by a collapse into an accretion-induced black hole is examined in the framework of a galactic chemical evolution model. The constraints on this model imposed by observations of extremely metal-poor stars are explained, and the upper limits in the [Sr/Ba] distributions are found to be related to the nuclearmore » EOS in a collapse scenario. The scatter in [Sr/Ba] and [Sr/Eu] as a function of metallicity has been found to be consistent with turbulent ejection in core-collapse supernovae. Adaptations of this model are evaluated to account for the scatter in isotopic observables. This is done by assuming mixing in ejecta in a supernova event. Stiff EOS are eliminated by this model.« less
Search for thermal X-ray features from the Crab nebula with the Hitomi soft X-ray spectrometer
NASA Astrophysics Data System (ADS)
Hitomi Collaboration; Aharonian, Felix; Akamatsu, Hiroki; Akimoto, Fumie; Allen, Steven W.; Angelini, Lorella; Audard, Marc; Awaki, Hisamitsu; Axelsson, Magnus; Bamba, Aya; Bautz, Marshall W.; Blandford, Roger; Brenneman, Laura W.; Brown, Gregory V.; Bulbul, Esra; Cackett, Edward M.; Chernyakova, Maria; Chiao, Meng P.; Coppi, Paolo S.; Costantini, Elisa; de Plaa, Jelle; de Vries, Cor P.; den Herder, Jan-Willem; Done, Chris; Dotani, Tadayasu; Ebisawa, Ken; Eckart, Megan E.; Enoto, Teruaki; Ezoe, Yuichiro; Fabian, Andrew C.; Ferrigno, Carlo; Foster, Adam R.; Fujimoto, Ryuichi; Fukazawa, Yasushi; Furuzawa, Akihiro; Galeazzi, Massimiliano; Gallo, Luigi C.; Gandhi, Poshak; Giustini, Margherita; Goldwurm, Andrea; Gu, Liyi; Guainazzi, Matteo; Haba, Yoshito; Hagino, Kouichi; Hamaguchi, Kenji; Harrus, Ilana M.; Hatsukade, Isamu; Hayashi, Katsuhiro; Hayashi, Takayuki; Hayashida, Kiyoshi; Hiraga, Junko S.; Hornschemeier, Ann; Hoshino, Akio; Hughes, John P.; Ichinohe, Yuto; Iizuka, Ryo; Inoue, Hajime; Inoue, Yoshiyuki; Ishida, Manabu; Ishikawa, Kumi; Ishisaki, Yoshitaka; Kaastra, Jelle; Kallman, Tim; Kamae, Tsuneyoshi; Kataoka, Jun; Katsuda, Satoru; Kawai, Nobuyuki; Kelley, Richard L.; Kilbourne, Caroline A.; Kitaguchi, Takao; Kitamoto, Shunji; Kitayama, Tetsu; Kohmura, Takayoshi; Kokubun, Motohide; Koyama, Katsuji; Koyama, Shu; Kretschmar, Peter; Krimm, Hans A.; Kubota, Aya; Kunieda, Hideyo; Laurent, Philippe; Lee, Shiu-Hang; Leutenegger, Maurice A.; Limousin, Olivier; Loewenstein, Michael; Long, Knox S.; Lumb, David; Madejski, Greg; Maeda, Yoshitomo; Maier, Daniel; Makishima, Kazuo; Markevitch, Maxim; Matsumoto, Hironori; Matsushita, Kyoko; McCammon, Dan; McNamara, Brian R.; Mehdipour, Missagh; Miller, Eric D.; Miller, Jon M.; Mineshige, Shin; Mitsuda, Kazuhisa; Mitsuishi, Ikuyuki; Miyazawa, Takuya; Mizuno, Tsunefumi; Mori, Hideyuki; Mori, Koji; Mukai, Koji; Murakami, Hiroshi; Mushotzky, Richard F.; Nakagawa, Takao; Nakajima, Hiroshi; Nakamori, Takeshi; Nakashima, Shinya; Nakazawa, Kazuhiro; Nobukawa, Kumiko K.; Nobukawa, Masayoshi; Noda, Hirofumi; Odaka, Hirokazu; Ohashi, Takaya; Ohno, Masanori; Okajima, Takashi; Ota, Naomi; Ozaki, Masanobu; Paerels, Frits; Paltani, Stéphane; Petre, Robert; Pinto, Ciro; Porter, Frederick S.; Pottschmidt, Katja; Reynolds, Christopher S.; Safi-Harb, Samar; Saito, Shinya; Sakai, Kazuhiro; Sasaki, Toru; Sato, Goro; Sato, Kosuke; Sato, Rie; Sato, Toshiki; Sawada, Makoto; Schartel, Norbert; Serlemtsos, Peter J.; Seta, Hiromi; Shidatsu, Megumi; Simionescu, Aurora; Smith, Randall K.; Soong, Yang; Stawarz, Łukasz; Sugawara, Yasuharu; Sugita, Satoshi; Szymkowiak, Andrew; Tajima, Hiroyasu; Takahashi, Hiromitsu; Takahashi, Tadayuki; Takeda, Shin'ichiro; Takei, Yoh; Tamagawa, Toru; Tamura, Takayuki; Tanaka, Takaaki; Tanaka, Yasuo; Tanaka, Yasuyuki T.; Tashiro, Makoto S.; Tawara, Yuzuru; Terada, Yukikatsu; Terashima, Yuichi; Tombesi, Francesco; Tomida, Hiroshi; Tsuboi, Yohko; Tsujimoto, Masahiro; Tsunemi, Hiroshi; Tsuru, Takeshi Go; Uchida, Hiroyuki; Uchiyama, Hideki; Uchiyama, Yasunobu; Ueda, Shutaro; Ueda, Yoshihiro; Uno, Shin'ichiro; Urry, C. Megan; Ursino, Eugenio; Watanabe, Shin; Werner, Norbert; Wilkins, Dan R.; Williams, Brian J.; Yamada, Shinya; Yamaguchi, Hiroya; Yamaoka, Kazutaka; Yamasaki, Noriko Y.; Yamauchi, Makoto; Yamauchi, Shigeo; Yaqoob, Tahir; Yatsu, Yoichi; Yonetoku, Daisuke; Zhuravleva, Irina; Zoghbi, Abderahmen; Tominaga, Nozomu; Moriya, Takashi J.
2018-03-01
The Crab nebula originated from a core-collapse supernova (SN) explosion observed in 1054 AD. When viewed as a supernova remnant (SNR), it has an anomalously low observed ejecta mass and kinetic energy for an Fe-core-collapse SN. Intensive searches have been made for a massive shell that solves this discrepancy, but none has been detected. An alternative idea is that SN 1054 is an electron-capture (EC) explosion with a lower explosion energy by an order of magnitude than Fe-core-collapse SNe. X-ray imaging searches were performed for the plasma emission from the shell in the Crab outskirts to set a stringent upper limit on the X-ray emitting mass. However, the extreme brightness of the source hampers access to its vicinity. We thus employed spectroscopic technique using the X-ray micro-calorimeter on board the Hitomi satellite. By exploiting its superb energy resolution, we set an upper limit for emission or absorption features from as yet undetected thermal plasma in the 2-12 keV range. We also re-evaluated the existing Chandra and XMM-Newton data. By assembling these results, a new upper limit was obtained for the X-ray plasma mass of ≲ 1 M⊙ for a wide range of assumed shell radius, size, and plasma temperature values both in and out of collisional equilibrium. To compare with the observation, we further performed hydrodynamic simulations of the Crab SNR for two SN models (Fe-core versus EC) under two SN environments (uniform interstellar medium versus progenitor wind). We found that the observed mass limit can be compatible with both SN models if the SN environment has a low density of ≲ 0.03 cm-3 (Fe core) or ≲ 0.1 cm-3 (EC) for the uniform density, or a progenitor wind density somewhat less than that provided by a mass loss rate of 10-5 M⊙ yr-1 at 20 km s-1 for the wind environment.
Abrupt climate change and collapse of deep-sea ecosystems
Yasuhara, Moriaki; Cronin, T. M.; Demenocal, P.B.; Okahashi, H.; Linsley, B.K.
2008-01-01
We investigated the deep-sea fossil record of benthic ostracodes during periods of rapid climate and oceanographic change over the past 20,000 years in a core from intermediate depth in the northwestern Atlantic. Results show that deep-sea benthic community "collapses" occur with faunal turnover of up to 50% during major climatically driven oceanographic changes. Species diversity as measured by the Shannon-Wiener index falls from 3 to as low as 1.6 during these events. Major disruptions in the benthic communities commenced with Heinrich Event 1, the Inter-Aller??d Cold Period (IACP: 13.1 ka), the Younger Dryas (YD: 12.9-11.5 ka), and several Holocene Bond events when changes in deep-water circulation occurred. The largest collapse is associated with the YD/IACP and is characterized by an abrupt two-step decrease in both the upper North Atlantic Deep Water assemblage and species diversity at 13.1 ka and at 12.2 ka. The ostracode fauna at this site did not fully recover until ???8 ka, with the establishment of Labrador Sea Water ventilation. Ecologically opportunistic slope species prospered during this community collapse. Other abrupt community collapses during the past 20 ka generally correspond to millennial climate events. These results indicate that deep-sea ecosystems are not immune to the effects of rapid climate changes occurring over centuries or less. ?? 2008 by The National Academy of Sciences of the USA.
A long time ago in a building not far away...
2007-04-01
Post COLD WAR – PRESENT) THIRD SPACE AGE (SPECULATIVE) SIGNALING EVENT − Sputnik 1957 − Collapse of the USSR in 1991 − War extended to space...Post COLD WAR – PRESENT) THIRD SPACE AGE (SPECULATIVE) SATELLITE OWNERS − Mostly single states −Some single states −Some multi-national consortia...AGE (Post COLD WAR – PRESENT) THIRD SPACE AGE (SPECULATIVE) SECURITY SECTOR FOCUS −Intelligence/ISR −Reduce fog −Increase transparency −Treaty
Hydroacoustic monitoring of a salt cavity: an analysis of precursory events of the collapse
NASA Astrophysics Data System (ADS)
Lebert, F.; Bernardie, S.; Mainsant, G.
2011-09-01
One of the main features of "post mining" research relates to available methods for monitoring mine-degradation processes that could directly threaten surface infrastructures. In this respect, GISOS, a French scientific interest group, is investigating techniques for monitoring the eventual collapse of underground cavities. One of the methods under investigation was monitoring the stability of a salt cavity through recording microseismic-precursor signals that may indicate the onset of rock failure. The data were recorded in a salt mine in Lorraine (France) when monitoring the controlled collapse of 2 000 000 m3 of rocks surrounding a cavity at 130 m depth. The monitoring in the 30 Hz to 3 kHz frequency range highlights the occurrence of events with high energy during periods of macroscopic movement, once the layers had ruptured; they appear to be the consequence of the post-rupture rock movements related to the intense deformation of the cavity roof. Moreover the analysis shows the presence of some interesting precursory signals before the cavity collapsed. They occurred a few hours before the failure phases, when the rocks were being weakened and damaged. They originated from the damaging and breaking process, when micro-cracks appear and then coalesce. From these results we expect that deeper signal analysis and statistical analysis on the complete event time distribution (several millions of files) will allow us to finalize a complete typology of each signal families and their relations with the evolution steps of the cavity over the five years monitoring.
Blue straggler formation at core collapse
NASA Astrophysics Data System (ADS)
Banerjee, Sambaran
Among the most striking feature of blue straggler stars (BSS) in globular clusters is the presence of multiple sequences of BSSs in the colour-magnitude diagrams (CMDs) of several globular clusters. It is often envisaged that such a multiple BSS sequence would arise due a recent core collapse of the host cluster, triggering a number of stellar collisions and binary mass transfers simultaneously over a brief episode of time. Here we examine this scenario using direct N-body computations of moderately-massive star clusters (of order 104 {M⊙). As a preliminary attempt, these models are initiated with ≈8-10 Gyr old stellar population and King profiles of high concentrations, being ``tuned'' to undergo core collapse quickly. BSSs are indeed found to form in a ``burst'' at the onset of the core collapse and several of such BS-bursts occur during the post-core-collapse phase. In those models that include a few percent primordial binaries, both collisional and binary BSSs form after the onset of the (near) core-collapse. However, there is as such no clear discrimination between the two types of BSSs in the corresponding computed CMDs. We note that this may be due to the less number of BSSs formed in these less massive models than that in actual globular clusters.
A Subject-Specific Acoustic Model of the Upper Airway for Snoring Sounds Generation
Saha, Shumit; Bradley, T. Douglas; Taheri, Mahsa; Moussavi, Zahra; Yadollahi, Azadeh
2016-01-01
Monitoring variations in the upper airway narrowing during sleep is invasive and expensive. Since snoring sounds are generated by air turbulence and vibrations of the upper airway due to its narrowing; snoring sounds may be used as a non-invasive technique to assess upper airway narrowing. Our goal was to develop a subject-specific acoustic model of the upper airway to investigate the impacts of upper airway anatomy, e.g. length, wall thickness and cross-sectional area, on snoring sounds features. To have a subject-specific model for snoring generation, we used measurements of the upper airway length, cross-sectional area and wall thickness from every individual to develop the model. To validate the proposed model, in 20 male individuals, intensity and resonant frequencies of modeled snoring sounds were compared with those measured from recorded snoring sounds during sleep. Based on both modeled and measured results, we found the only factor that may positively and significantly contribute to snoring intensity was narrowing in the upper airway. Furthermore, measured resonant frequencies of snoring were inversely correlated with the upper airway length, which is a risk factor for upper airway collapsibility. These results encourage the use of snoring sounds analysis to assess the upper airway anatomy during sleep. PMID:27210576
NASA Astrophysics Data System (ADS)
Howard, K. A.
2009-12-01
The 1968 collapse structure of Fernandina caldera (1.5 km3 collapsed) and also the smaller Darwin Bay caldera in Galápagos each closely resembles morphologically the structural zoning of features found in depressions collapsed into nuclear-explosion cavities (“sinks” of Houser, 1969) and in coherent sandbox-collapse models. Coherent collapses characterized by faulting, folding, and organized structure contrast with spalled pit craters (and lab experiments with collapsed powder) where disorganized piles of floor rubble result from tensile failure of the roof. Subsidence in coherent mode, whether in weak sand in the lab, stronger desert alluvium for nuclear-test sinks, or in hard rock for calderas, exhibits consistent morphologic zones. Characteristically in the sandbox and the nuclear-test analogs these include a first-formed central plug that drops along annular reverse faults. This plug and a surrounding inward-tilted or monoclinal ring (hanging wall of the reverse fault) contract as the structure expands outward by normal faulting, wherein peripheral rings of distending material widen the upper part of the structure along inward-dipping normal faults and compress inner zones and help keep them intact. In Fernandina, a region between the monocline and the outer zone of normal faulting is interpreted, by comparison to the analogs, to overlie the deflation margin of an underlying magma chamber. The same zoning pattern is recognized in structures ranging from sandbox subsidence features centimeters across, to Alae lave lake and nuclear-test sinks tens to hundreds of meters across, to Fenandina’s 2x4 km-wide collapse, to Martian calderas tens of kilometers across. Simple dimensional analysis using the height of cliffs as a proxie for material strength implies that the geometric analogs are good dynamic analogs, and validates that the pattern of both reverse and normal faulting that has been reported consistently from sandbox modeling applies widely to calderas.
An upper limit on Early Mars atmospheric pressure from small ancient craters
NASA Astrophysics Data System (ADS)
Kite, E. S.; Williams, J.; Lucas, A.; Aharonson, O.
2012-12-01
Planetary atmospheres brake, ablate, and disrupt small asteroids and comets, filtering out small hypervelocity surface impacts and causing fireballs, airblasts, meteors, and meteorites. Hypervelocity craters <1 km diameter on Earth are typically caused by irons (because stones are more likely to break up), and the smallest hypervelocity craters near sea-level on Earth are ~20 m in diameter. 'Zap pits' as small as 30 microns are known from the airless moon, but the other airy worlds show the effects of progressively thicker atmospheres:- the modern Mars atmosphere is marginally capable of removing >90% of the kinetic energy of >240 kg iron impactors; Titan's paucity of small craters is consistent with a model predicting atmospheric filtering of craters smaller than 6-8km; and on Venus, craters below ~20 km diameter are substantially depleted. Changes in atmospheric CO2 concentration are believed to be the single most important control on Mars climate evolution and habitability. Existing data requires an early epoch of massive atmospheric loss to space; suggests that the present-day rate of escape to space is small; and offers only limited evidence for carbonate formation. Existing evidence has not led to convergence of atmosphere-evolution models, which must balance poorly understood fluxes from volcanic degassing, surface weathering, and escape to space. More direct measurements are required in order to determine the history of CO2 concentrations. Wind erosion and tectonics exposes ancient surfaces on Mars, and the size-frequency distribution of impacts on these surfaces has been previously suggested as a proxy time series of Mars atmospheric thickness. We will present a new upper limit on Early Mars atmospheric pressure using the size-frequency distribution of 20-100m diameter ancient craters in Aeolis Dorsa, validated using HiRISE DTMs, in combination with Monte Carlo simulations of the effect of paleo-atmospheres of varying thickness on the crater flux. These craters are interbedded with river deposits, and so the atmospheric state they record corresponds to an era when Mars was substantially wetter than the present, probably >3.7 Ga. An important caveat is that our technique cannot exclude atmospheric collapse-reinflation cycles on timescales much shorter than the sedimentary basin-filling time, so it sets an upper limit on the density of a thick stable paleoatmosphere. We will discuss our results in relation to previous estimates of ancient atmospheric pressure, and place new constraints on models of Early Mars climate.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Antrim, L.D.; Thom, R.M.; Gardiner, W.W.
1993-09-01
In 1988, the US Army Corps of Engineers and the City of Seattle placed material on the upper beach at Lincoln Park, in West Seattle, Washington. The fill served to mitigate shoreline erosion that had caused undercutting and collapse of the seawall in several places. A series of pre- and post-construction studies have been conducted to assess the impacts to marine biota of fill placement and movement of surface substrate. This study was designed to monitor infaunal bivalves and eelgrass from intertidal areas in and adjacent to the area of original fill placement. Findings from this survey were compared tomore » previous survey results to determine (1) if recruitment of infaunal bivalves to the fill area has occurred, (2) if infaunal bivalve densities outside the fill area are stable, and (3) if eelgrass distribution and abundance have remained stable along the adjacent shoreline. To maximize comparability of findings from this survey with previous studies, sampling techniques, transects, and tidal elevations were consistent with previous studies at this site.« less
OVERVIEW OF CYANIDE PLANT REMAINS, TAILINGS PILES, PARKING LOT, AND ...
OVERVIEW OF CYANIDE PLANT REMAINS, TAILINGS PILES, PARKING LOT, AND MINE MANAGER'S HOME, LOOKING SOUTH SOUTHEAST. RIGHT, TAILINGS PILES ARE AT CENTER WITH CYANIDE PLANT FOUNDATIONS TO THE LEFT OF THE PILES. PARKING LOT IS AT UPPER LEFT. THE AREA BETWEEN THE COLLAPSED TANK AT CENTER LEFT AND THE REMAINS OF THE MANAGER'S HOUSE AT LOWER RIGHT IS A TAILINGS HOLDING AREA. TAILINGS FROM THE MILL WERE HELD HERE. THE LARGE SETTLING TANKS WERE CHARGED FROM THIS HOLDING AREA BY A TRAM ON RAILS AND BY A SLUICEWAY SEEN AS THE DARK SPOT ON THE CENTER LEFT EDGE OF THE FRAME. AFTER THE TAILINGS WERE LEACHED, THEY WERE DEPOSITED ON THE LARGE WASTE PILE AT CENTER RIGHT. THE TANK AT CENTER RIGHT EDGE IS WHERE THE WATER PIPELINE ENTERED THE WORKS. A STRAIGHT LINE OF POSTS IN THE GROUND GO ACROSS THE CENTER FROM LEFT TO RIGHT, WHICH ORIGINALLY SUSPENDED THE WATER PIPELINE GOING FROM THE WATER HOLDING TANK AT RIGHT UP TO THE SECONDARY WATER TANKS ABOVE THE MILL. - Keane Wonder Mine, Park Route 4 (Daylight Pass Cutoff), Death Valley Junction, Inyo County, CA
Eakins, Barry W.; Robinson, Joel E.; Kanamatsu, Toshiya; Naka, Jiro; Smith, John R.; Takahashi, Eiichi; Clague, David A.
2003-01-01
Hawaiian volcanoes typically evolve in four stages as volcanism waxes and wanes: (1) early alkalic, when volcanism originates on the deep sea floor; (2) shield, when roughly 95 percent of a volcano's volume is emplaced; (3) post-shield alkalic, when small-volume eruptions build scattered cones that thinly cap the shield-stage lavas; and (4) rejuvenated, when lavas of distinct chemistry erupt following a lengthy period of erosion and volcanic quiescence. During the early alkalic and shield stages, two or more elongate rift zones may develop as flanks of the volcano separate. Mantle-derived magma rises through a vertical conduit and is temporarily stored in a shallow summit reservoir from which magma may erupt within the summit region or be injected laterally into the rift zones. The ongoing activity at Kilauea's Pu?u ?O?o cone that began in January 1983 is one such rift-zone eruption. The rift zones commonly extend deep underwater, producing submarine eruptions of bulbous pillow lava. Once a volcano has grown above sea level, subaerial eruptions produce lava flows of jagged, clinkery ?a?a or smooth, ropy pahoehoe. If the flows reach the ocean they are rapidly quenched by seawater and shatter, producing a steep blanket of unstable volcanic sediment that mantles the upper submarine slopes. Above sea level then, the volcanoes develop the classic shield profile of gentle lava-flow slopes, whereas below sea level slopes are substantially steeper. While the volcanoes grow rapidly during the shield stage, they may also collapse catastrophically, generating giant landslides and tsunami, or fail more gradually, forming slumps. Deformation and seismicity along Kilauea's south flank indicate that slumping is occurring there today. Loading of the underlying Pacific Plate by the growing volcanic edifices causes subsidence, forming deep basins at the base of the volcanoes. Once volcanism wanes and lava flows no longer reach the ocean, the volcano continues to submerge, while erosion incises deep river valleys, such as those on the Island of Kaua?i. The edges of the submarine terraces that ring the islands, thus, mark paleocoastlines that are now as much as 2,000 m underwater, many of which are capped by drowned coral reefs.
Geologic Setting of Mosul Dam and Its Engineering Implications
2007-09-01
thought that an increase in vol- ume, produced during alteration of interbedded anhydrite to gypsum, generated sufficient pressure to fracture the...construction.. ..................................................................23 Figure 8. Geologic sections with water- pressure test values and...contains fragments or clasts of limestone, dolomite , or larger pieces of insoluble rocks of collapsed material. The upper portion of the accumulation
Nucleosynthesis in Core-Collapse Supernovae
NASA Astrophysics Data System (ADS)
Stevenson, Taylor Shannon; Viktoria Ohstrom, Eva; Harris, James Austin; Hix, William R.
2018-01-01
The nucleosynthesis which occurs in core-collapse supernovae (CCSN) is one of the most important sources of elements in the universe. Elements from Oxygen through Iron come predominantly from supernovae, and contributions of heavier elements are also possible through processes like the weak r-process, the gamma process and the light element primary process. The composition of the ejecta depends on the mechanism of the explosion, thus simulations of high physical fidelity are needed to explore what elements and isotopes CCSN can contribute to Galactic Chemical Evolution. We will analyze the nucleosynthesis results from self-consistent CCSN simulations performed with CHIMERA, a multi-dimensional neutrino radiation-hydrodynamics code. Much of our understanding of CCSN nucleosynthesis comes from parameterized models, but unlike CHIMERA these fail to address essential physics, including turbulent flow/instability and neutrino-matter interaction. We will present nucleosynthesis predictions for the explosion of a 9.6 solar mass first generation star, relying both on results of the 160 species nuclear reaction network used in CHIMERA within this model and on post-processing with a more extensive network. The lowest mass iron core-collapse supernovae, like this model, are distinct from their more massive brethren, with their explosion mechanism and nucleosynthesis being more like electron capture supernovae resulting from Oxygen-Neon white dwarves. We will highlight the differences between the nucleosynthesis in this model and more massive supernovae. The inline 160 species network is a feature unique to CHIMERA, making this the most sophisticated model to date for a star of this type. We will discuss the need and mechanism to extrapolate the post-processing to times post-simulation and analyze the uncertainties this introduces for supernova nucleosynthesis. We will also compare the results from the inline 160 species network to the post-processing results to study further uncertainties introduced by post-processing. This work is supported by the U.S. Department of Energy, Office of Nuclear Physics, and the National Science Foundation Nuclear Theory Program (PHY-1516197).
Shah, Amir Ali; Charon, Jean Pierre
2015-06-01
Haemosuccus Pancreaticus is defined as upper gastro intestinal (GI) bleeding from the ampula of vater via the pancreatic duct. It is most commonly associated with pancreatic inflammation, erosion of the pancrease by aneurysm or pseudo-aneurysm of the splenic artery. We report a 69 year old man with previous history of acute pancreatitis who was admitted with recurrent haematemesis. Initial upper GI endocopy was normal, while admitted, he collapse with abdominal pain and hypotension. He was resuscitated with blood and intravenous fluid. Repeat upper GI endocopy showed fresh blood in the duodenum, but no active bleeding site was demonstrated. An urgent coeliac axis CT angiogram was done which showed an splenic artery pseudo-aneurysm, which was successfully embolized. Patient is well 9 months after the procedure. This case highlights the importance of considering coeliac axis CT angiogram as part of investigation for obscure GI bleeding.
Schiefer, Matthew; Gamble, Jenniffer; Strohl, Kingman Perkins
2018-06-07
Obstructive sleep apnea (OSA) is a disorder characterized by collapse of the velopharynx and/or oropharynx during sleep when drive to the upper airway is reduced. Here, we explore an indirect approach for activation of upper airway muscles which might affect airway dynamics- unilateral electrical stimulation of the afferent fibers of the sciatic nerve- in an anesthetized rabbit model. A nerve cuff electrode was placed around the sciatic and hypoglossal nerves to deliver stimulus while air flow, air pressure, and alae nasi electromyogram (EMG) were monitored both prior to and after sciatic transection. Sciatic nerve stimulation increased respiratory effort, rate, and alae nasi EMG, which persisted for seconds after stimulation; however, upper airway resistance was unchanged. Hypoglossal stimulation reduced resistance without altering drive. While sciatic nerve stimulation is not ideal for treating obstructive sleep apnea, it remains a target for altering respiratory drive.
A Simple Model for Human and Nature Interaction
NASA Astrophysics Data System (ADS)
Motesharrei, S.; Rivas, J.; Kalnay, E.
2012-12-01
There are widespread concerns that current trends in population and resource-use are unsustainable, but the possibilities of an overshoot and collapse remain unclear and controversial. Collapses of civilizations have occurred many times in the past 5000 years, often followed by centuries of economic, intellectual, and population decline. Many different natural and social phenomena have been invoked to explain specific collapses, but a general explanation remains elusive. Two important features seem to appear across societies that have collapsed: Ecological Strain and Economic Stratification. Our new model (Human And Nature DYnamics, HANDY) has just four equations that describe the evolution of Elites, Commoners, Nature, and Wealth. Mechanisms leading to collapse are discussed and the measure "Carrying Capacity" is developed and defined. The model shows that societal collapse can happen due to either one of two independent factors: (1) over-consumption of natural resources, and/or (2) deep inequity between Elites and Commoners. The model also portrays two distinct types of collapse: (i) collapse followed by recovery of nature, and (ii) full collapse. The model suggests that the estimation of Carrying Capacity is a practical means for early detection of a collapse. Collapse can be avoided, and population can reach a sustainable equilibrium, if the rate of depletion of nature is reduced to a sustainable level, and if resources are distributed in a reasonably equitable fashion.; A type-ii (full) collapse is shown in this figure. With high inequality and high depletion, societies are doomed to collapse. Wealth starts to decrease when population rises above the carrying capacity. The large gap between carrying capacity and its maximum is a result of depletion factor being much larger than the sustainable limit. ; It is possible to overshoot, oscillate, and eventually converge to an equilibrium, even in an inequitable society. However, it requires policies that control birth rates and inequality. Additionally, depletion (production) must be kept within a reasonable range.
Volcanologic and petrologic evolution of Antuco-Sierra Velluda, Southern Andes, Chile
NASA Astrophysics Data System (ADS)
Martínez, Paola; Singer, Brad S.; Roa, Hugo Moreno; Jicha, Brian R.
2018-01-01
The Andean Southern Volcanic Zone comprises > 30 active arc front volcanoes that grew over periods of hundreds of thousands of years. Quantifying the rates at which these volcanoes grow is key to appreciating geological hazards, clarifying petrologic evolution, and exploring possible relationships between volcanism, ice loading, and climate. The integration of precise geochronology and geologic mapping, together with new lava compositions and volume estimates, reveal the evolution of the Antuco-Sierra Velluda volcanic complex at 37.2°S. Thirty-one new 40Ar/39Ar age determinations illuminate a punctuated eruptive history that spans at least 430 kyr. Sierra Velluda comprises 130 km3 and began to grow prior to 426.8 ka. A lacuna in the volcanic record between 343.5 and 150.4 ka coincides with glaciations associated with marine isotope stages (MIS) 10 and 8, although shallow intrusions were emplaced at 207.0 and 190.0 ka. Antuco began to grow rapidly on the northeast flank of Sierra Velluda, erupting > 60 km3 of lava during three phases: (1) an early phase that began at 150.4 ka, (2) a post-MIS 2 phase between 16.3 and 6.2 ka, and (3) a post-sector collapse phase after 6.2 ka. Volcanism has been continuous during the last 100 kyr, with an average rate of cone growth during this period of 0.46 km3/kyr that has accelerated by about 50% during the past 6 kyr. Whereas Sierra Velluda erupted basaltic andesitic to andesitic (53.5 to 58.7 wt% SiO2) lavas, during the last expansion of glaciers between 130 and 17 ka, Early Antuco erupted a wider spectrum of lavas, ranging from basaltic andesite to dacite (52.0 to 64.5 wt% SiO2). Notably, eruptions following the last glacial termination at 17 ka produced basalts and basaltic andesites (50.9-53.7% SiO2), and following the 6.2 ka cone collapse they have been exclusively olivine basalt (50.9-53.0% SiO2) with > 5 wt% MgO. Thermodynamic and trace element modeling suggests that lavas from Sierra Velluda and Early Antuco reflect extensive fractional crystallization of parental basaltic magmas with low water content ( 1 wt%) at pressures between 0.9 and 1.5 kbar. In contrast, eruptions following rapid deglaciation tapped asthenospheric mantle-derived basalt that has been extensively modified by assimilation of partial melts of lower crustal rocks. A-2 Geochemical data (XRF-Replicates). A-3 Geochemical data (ICP-MS: International Standards).
Koo, Soo Kweon; Ahn, Gun Young; Choi, Jang Won; Kim, Young Jun; Jung, Sung Hoon; Moon, Ji Seung; Lee, Young Il
The key to successful treatment of OSAS is to individually tailor such treatment. Thus, it is very important to determine the severity of OSAS, its pattern, and the extent of collapse, by gender, age, and BMI. The objective of the study was to understand the characteristics of obstructive sleep apnea in postmenopausal women by comparing postmenopausal and premenopausal subjects, and men, using DISE. We hope that our work will help the medical community to consult on, diagnose, and treat OSAS more effectively. A total of 273 patients (195 males and 78 females) diagnosed with OSAS were enrolled. Female patients were divided into pre-menopausal (n=41) and post-menopausal patients (n=37). The group of post-menopausal female patients was matched with a group of male patients with similar age and body mass index (BMI). DISE findings were compared between pre-menopausal female patients and post-menopausal female patients, and also between post-menopausal female patients and male patients matched for age and BMI. Upon PSG examination, post-menopausal patients (who had a significantly higher BMI than did pre-menopausal patients; 25.6kg/m 2 vs. 23.5kg/m 2 ; p=0.019) tended to have a higher AHI and a lower lowest SaO 2 , but the differences did not attain statistical significance. With DISE analysis, post-menopausal female patients showed higher values in all obstruction sites, with significantly higher value in lateral diameter of retropalatal (1.49 vs. 0.90; p=0.001) and retrolingual levels (1.14 vs. 0.61; p=0.003) compared to pre-menopausal females patients. Post-menopausal female patients showed significantly more retrolingual collapse (antero-posterior, AP, p≤0.0001, and lateral diameter, p=0.042) in the lower BMI group (BMI<25) and more concentric retropalatal collapse (lateral diameter, p=0.017 and tonsillar obstruction, p=0.003) in higher BMI group (BMI≥25) than BMI and age matched male patients. Post-menopausal female patients showed a different pattern of airway obstruction compared to pre-menopausal female patients and male patients matched for age and BMI based on DISE findings. Copyright © 2016 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.
Fowler, Peter M; Duffield, Rob; Lu, Donna; Hickmans, Jeremy A; Scott, Tannath J
2016-10-01
To examine the effects of 24-h travel west across 11 time zones on subjective jet-lag and wellness responses together with self-reported sleep and upper respiratory symptoms in 18 professional rugby league players. Measures were obtained 1 or 2 d before (pretravel) and 2, 6, and 8 d after travel (post-2, post-6, and post-8) from Australia to the United Kingdom (UK) for the 2015 World Club Series. Compared with pretravel, subjective jet-lag remained significantly elevated on post-8 (3.1 ± 2.3, P < .05, d > 0.90), although it was greatest on post-2 (4.1 ± 1.4). Self-reported sleep-onset times were significantly earlier on post-2 than at all other time points (P < .05, d > 0.90), and large effect sizes suggested that wake times were earlier on post-2 than on post-6 and post-8 (d > 0.90). Although significantly more upper respiratory symptoms were reported on post-6 than at pretravel (P < .05, d ˃ 0.90), no incidence of injury and negligible changes in wellness and muscle strength and range of motion (P > .05, d < 0.90) were evident after travel. Results suggest that westward long-haul travel between Australia and the UK exacerbates subjective jet-lag and sleep responses, along with upper respiratory symptoms, in professional rugby league players. Of note, the increase in self-reported upper respiratory symptoms is a reminder that the demands of long-haul travel may be an additional concern in jet-lag for traveling athletes. However, due to the lack of sport-specific performance measures, it is still unclear whether international travel interferes with training to the extent that subsequent competition performance is impaired.
NASA Astrophysics Data System (ADS)
Kounov, Alexandre; Gerdjikov, Ianko; Vangelov, Dian; Balkanska, Eleonora; Lazarova, Anna; Georgiev, Stoyan; Blunt, Edward; Stockli, Daniel
2017-11-01
The Balkan fold-thrust belt, exposed in Bulgaria and north-east Serbia, is part of the north-east vergent segment of the bi-vergent Eastern Mediterranean Alpine orogen. It was formed during two distinct compressional stages; the first one lasted from the Middle Jurassic to the Early Cretaceous and the second from Late Cretaceous to the Paleogene. Although the compressional tectonic evolution of the Balkan fold-thrust belt since the Middle Jurassic and during most of the Mesozoic is relatively well studied, the final exhumation of the rocks of the belt during the Cenozoic has remained poorly understood. Here, we present the first thermochronological constraints, based on fission-track and [U-Th-(Sm)]/He analysis, showing that along the central part of the belt syn- to post-orogenic extension could have started as early as the middle Eocene. Low-temperature thermochronological analysis of samples collected from three areas reveals at least two phases of increased cooling and exhumation during the Cenozoic. The first exhumation phase took place between 44 and 30 Ma and appears to be related to the syn- to post-orogenic collapse coeval with the earliest Cenozoic extensional stage observed across the southern Balkan Peninsula. A period of relative quiescence (between 30 and 25 Ma) is followed by the next cooling stage, between 25 and 20 Ma, which appears to be related to late Oligocene to early Miocene crustal extension across the Balkan Peninsula. Extension accommodated by the late Miocene to Recent age Sub-Balkan Graben System does not appear to have produced exhumation of rocks from beneath 2-4 km depth, as it was not detected by the low-temperature thermochronological methods applied in this study.
The rise-time of Type II supernovae
NASA Astrophysics Data System (ADS)
González-Gaitán, S.; Tominaga, N.; Molina, J.; Galbany, L.; Bufano, F.; Anderson, J. P.; Gutierrez, C.; Förster, F.; Pignata, G.; Bersten, M.; Howell, D. A.; Sullivan, M.; Carlberg, R.; de Jaeger, T.; Hamuy, M.; Baklanov, P. V.; Blinnikov, S. I.
2015-08-01
We investigate the early-time light curves of a large sample of 223 Type II supernovae (SNe II) from the Sloan Digital Sky Survey and the Supernova Legacy Survey. Having a cadence of a few days and sufficient non-detections prior to explosion, we constrain rise-times, i.e. the durations from estimated first to maximum light, as a function of effective wavelength. At rest-frame g' band (λeff = 4722 Å), we find a distribution of fast rise-times with median of (7.5 ± 0.3) d. Comparing these durations with analytical shock models of Rabinak & Waxman and Nakar & Sari, and hydrodynamical models of Tominaga et al., which are mostly sensitive to progenitor radius at these epochs, we find a median characteristic radius of less than 400 solar radii. The inferred radii are on average much smaller than the radii obtained for observed red supergiants (RSG). Investigating the post-maximum slopes as a function of effective wavelength in the light of theoretical models, we find that massive hydrogen envelopes are still needed to explain the plateaus of SNe II. We therefore argue that the SN II rise-times we observe are either (a) the shock cooling resulting from the core collapse of RSG with small and dense envelopes, or (b) the delayed and prolonged shock breakout of the collapse of an RSG with an extended atmosphere or embedded within pre-SN circumstellar material.
NASA Astrophysics Data System (ADS)
Teza, Giordano; Galgaro, Antonio; Francese, Roberto; Ninfo, Andrea; Mariani, Rocco
2017-04-01
An early warning system has been implemented to monitor the Perarolo di Cadore landslide (North-Eastern Italian Alps), which is a slump whose induced risk is fairly high because a slope collapse could form a temporary dam on the underlying torrent and, therefore, could directly threaten the close village. A robotic total station (RTS) measures, with 6h returning time, the positions of 23 retro-reflectors placed on the landslide upper and middle sectors. The landslide's kinematical behavior derived from these near-real-time (NRT) surface displacements is interpreted on the basis of available geomorphological and geological information, geometrical data provided by some laser scanning and photogrammetric surveys, and a landslide model obtained by means of 3D Electrical Resistivity Tomography (3D ERT) measurements. In this way, an analysis of the time series provided by RTS and a pluviometer, which cover several years, allows the definition of some pre-alert and alert kinematical and rainfall thresholds. These thresholds, as well as the corresponding operational recommendations, are currently used for early warning purposes by Authorities involved in risk management for the Perarolo landslide. It should be noted the fact that, as new RTS and pluviometric data are available, the thresholds can be updated and, therefore, a fine tuning of the early warning system can be carried out in order to improve its performance. Although the proposed approach has been implemented in a particular case, it can be used to develop an early warning system based on NRT data in each site where a landslide threatens infrastructures and/or villages that cannot be relocated.
Supernova Neutrino-Burst Search with the AMANDA Detector
NASA Astrophysics Data System (ADS)
Neunhöffer, T.; AMANDA Collaboration
2001-08-01
The neutrino telescope AMANDA located deep in the South Pole ice has been used to search for bursts of low energy neutrinos originating from supernova collapses. In the data sets taken during 1997 and 1998 with 302 of the detector's optical modules no candidate events were found. With this detector configuration 70% of the galaxy is covered with 90% efficiency allowing for one background fake per year. An upper limit at the 90% c.l. on the rate of star collapses in the Milky Way is derived, yielding 4.3 events per year. The new supernova readout system, which has been installed in 2000 and 2001, is discussed. With the full (19string) system we expect to cover 97% of our galaxy.
Across the Great Divide. From a Welfare State to a New Market State: The Case of VET
ERIC Educational Resources Information Center
Ainley, Patrick
2007-01-01
This paper revisits the crucial period following the Arab oil boycott of 1973, when the welfare state in the UK finally collapsed along with the heavy industrial base upon which it rested. Unlike the post-war welfare-state "settlement", the new post-welfare market state was imposed by Margaret Thatcher's governments. It was marked for…
Power Lines: The Rhetoric of Maps as Social Change in the Post-Cold War Landscape
ERIC Educational Resources Information Center
Barney, Timothy
2009-01-01
After the fall of the Berlin Wall and the collapse of state socialism in Eastern and Central Europe, cartographers were faced with choices on how the new post-Cold War political landscape would be mapped. One such group called the Pluto Project had been producing atlases since 1981 with a progressive point of view about the nature of state power…
NASA Astrophysics Data System (ADS)
Torelli, Luigi; Grasso, Mario; Mazzoldi, Glauco; Peis, Davide
1998-11-01
Available multi- and single-channel seismic reflection profiles, calibrated by onshore borehole data, have been used for defining the structural styles in the shelf and slope of the Ionian Sea between Catania and Augusta (SE Sicily). The geological and geophysical data suggest that this area represents a segment of the foredeep-foreland system which collapsed after Late Pliocene times. The foundering was controlled by normal faults trending NE-SW, which flank the southern margin of the Catania foredeep. Onland, in outcrop, these faults appear largely to be post-dated by Lower Pleistocene sediments, nearshore carbonates passing laterally into basinal clays, which lie unconformably upon older substrata. Offshore, close to the southern edge of the foredeep, seismic lines allow recognition of two distinct units: a syn-rift wedge (Upper Pliocene submarine tholeiites and sediments), and a post-rift sequence which can be correlated with Lower Pleistocene carbonates, sands and clays recognisable on land, both in outcrop and by borehole data. The true frontal part of the thrust belt, as detected by the seismic lines, occupies the inner part of the area investigated and is buried by Upper Pliocene and Lower Pleistocene sediments. However, the compressive deformation seems to propagate toward the south-southeast by means of growing detachment levels developing at depth within Pleistocene marine clays, for a length of about 10 km, ahead of the present-day thrust front. Offshore, the faults trending NE-SW are dissected towards the east by faults trending NNW-SSE, subparallel to the Malta Escarpment, which flank the edge of the submerged Messina Rise. These faults, originating in a steep scarp which drops eastwards to the deep Ionian basin, have triggered submarine slides and affected the present-day seafloor sediments. As shown by seismic lines and as stressed by the modern seismicity of the area, some of the faults along the Malta Escarpment could be still active.
NASA Astrophysics Data System (ADS)
Tao, Yu; He, Yangbo; Duan, Xiaoqian; Zou, Ziqiang; Lin, Lirong; Chen, Jiazhou
2017-10-01
Soil preferential flow (PF) has important effects on rainfall infiltration, moisture distribution, and hydrological and ecological process; but it is very difficult to monitor and characterize on a slope. In this paper, soil water and soil temperature at 20, 40, 60, 80 cm depths in six positions were simultaneously monitored at high frequency to confirm the occurrence of PF at a typical Benggang slope underlain granite residual deposits, and to determine the interaction of soil moisture distribution and Benggang erosion. In the presence of PF, the soil temperature was first (half to one hour) governed by the rainwater temperature, then (more than one hour) governed by the upper soil temperature; in the absence of PF (only matrix flow, MF), the soil temperature was initially governed by the upper soil temperature, then by the rainwater temperature. The results confirmed the water replacement phenomenon in MF, thus it can be distinguished from PF by additional temperature monitoring. It indicates that high frequency moisture and temperature monitoring can determine the occurrence of PF and reveal the soil water movement. The distribution of soil water content and PF on the different positions of the slope showed that a higher frequency of PF resulted in a higher variation of average of water content. The frequency of PF at the lower position can be three times as that of the upper position, therefore, the variation coefficient of soil water content increased from 4.67% to 12.68% at the upper position to 8.18%-33.12% at the lower position, where the Benggang erosion (soil collapse) was more possible. The results suggest strong relationships between PF, soil water variation, and collapse activation near the Benggang wall.
Signatures of the collapse and incipient recovery of an overexploited marine ecosystem
Thompson, Patrick L.; Ball, R. Aaron; Fortin, Marie-Josée; Gouhier, Tarik C.; Link, Heike; Moritz, Charlotte; Nenzen, Hedvig; Stanley, Ryan R. E.; Taranu, Zofia E.; Gonzalez, Andrew; Guichard, Frédéric; Pepin, Pierre
2017-01-01
The Northwest Atlantic cod stocks collapsed in the early 1990s and have yet to recover, despite the subsequent establishment of a continuing fishing moratorium. Efforts to understand the collapse and lack of recovery have so far focused mainly on the dynamics of commercially harvested species. Here, we use data from a 33-year scientific trawl survey to determine to which degree the signatures of the collapse and recovery of the cod are apparent in the spatial and temporal dynamics of the broader groundfish community. Over this 33-year period, the groundfish community experienced four phases of change: (i) a period of rapid, synchronous biomass collapse in most species, (ii) followed by a regime shift in community composition with a concomitant loss of functional diversity, (iii) followed in turn by periods of slow compositional recovery, and (iv) slow biomass growth. Our results demonstrate how a community-wide perspective can reveal new aspects of the dynamics of collapse and recovery unavailable from the analysis of individual species or a combination of a small number of species. Overall, we found evidence that such community-level signals should be useful for designing more effective management strategies to ensure the persistence of exploited marine ecosystems. PMID:28791149
NASA Astrophysics Data System (ADS)
Michael, L.; Nikiforakis, N.
2018-02-01
This work is concerned with the effect of cavity collapse in non-ideal explosives as a means of controlling their sensitivity. The main objective is to understand the origin of localised temperature peaks (hot spots) which play a leading order role at the early stages of ignition. To this end, we perform two- and three-dimensional numerical simulations of shock-induced single gas-cavity collapse in liquid nitromethane. Ignition is the result of a complex interplay between fluid dynamics and exothermic chemical reaction. In order to understand the relative contribution between these two processes, we consider in this first part of the work the evolution of the physical system in the absence of chemical reactions. We employ a multi-phase mathematical formulation which can account for the large density difference across the gas-liquid material interface without generating spurious temperature peaks. The mathematical and physical models are validated against experimental, analytic, and numerical data. Previous inert studies have identified the impact of the upwind (relative to the direction of the incident shock wave) side of the cavity wall to the downwind one as the main reason for the generation of a hot spot outside of the cavity, something which is also observed in this work. However, it is also apparent that the topology of the temperature field is more complex than previously thought and additional hot spot locations exist, which arise from the generation of Mach stems rather than jet impact. To explain the generation mechanisms and topology of the hot spots, we carefully follow the complex wave patterns generated in the collapse process and identify specifically the temperature elevation or reduction generated by each wave. This enables tracking each hot spot back to its origins. It is shown that the highest hot spot temperatures can be more than twice the post-incident shock temperature of the neat material and can thus lead to ignition. By comparing two-dimensional and three-dimensional simulation results in the context of the maximum temperature observed in the domain, it is apparent that three-dimensional calculations are necessary in order to avoid belated ignition times in reactive scenarios.
NASA Astrophysics Data System (ADS)
Hamiel, Y.; Barbot, S.; Fialko, Y.
2006-12-01
We use ENVISAT Advanced Synthetic Aperture Radar data and SPOT optical imagery to investigate the co- seismic and post-seismic deformation due to the September 27th 2003, Mw7.3 Altai earthquake that occurred in the Chuya Basin area near the Russia-China-Mongolia border. Based on the SAR and SPOT data we determined the location of the ruptured fault trace and developed a co-seismic slip model for the Altai earthquake. The geodetic moment from our slip model was found to be consistent with the seismic moment determined from the teleseismic data. While the epicentral area of the Altai earthquake is not optimal for radar interferometry (in particular, due to temporal decorrelation), we were able to detect the post-seismic relaxation signal over a time period of 2.5 years following the earthquake. The signal is robust in that it allows us to discriminate between several commonly considered mechanisms of post-seismic relaxation. We find that the post-earthquake InSAR data do not warrant poro-elastic rebound in the upper crust, or simple Maxwellian visco-elastic relaxation in the upper mantle. The data can be explained in terms of afterslip on a downdip extension of the earthquake rupture, non-linear visco-elastic rheology of the ductile substrate (kinematically, similar to afterslip at early stages of relaxation), or the bulk visco-elastic relaxation in the lower crust. Continued InSAR observations may further constrain the mechanisms driving the post-seismic relaxation. The observed post-seismic deformation due to the Altai earthquake is qualitatively different from deformation due to other similar-size earthquakes (in particular, the Landers and Hector Mine earthquakes in the Mojave desert, southern California). These variations in the deformation pattern may be indicative of different rheologic structure of the continental lithosphere in different tectonically active areas.
NASA Astrophysics Data System (ADS)
Armstrong, Julian J.; Leigh, Matthew S.; Walton, Ian D.; Zvyagin, Andrei V.; Alexandrov, Sergey A.; Schwer, Stefan; Sampson, David D.; Hillman, David R.; Eastwood, Peter R.
2003-07-01
We describe a long-range optical coherence tomography system for size and shape measurement of large hollow organs in the human body. The system employs a frequency-domain optical delay line of a configuration that enables the combination of high-speed operation with long scan range. We compare the achievable maximum delay of several delay line configurations, and identify the configurations with the greatest delay range. We demonstrate the use of one such long-range delay line in a catheter-based optical coherence tomography system and present profiles of the human upper airway and esophagus in vivo with a radial scan range of 26 millimeters. Such quantitative upper airway profiling should prove valuable in investigating the pathophysiology of airway collapse during sleep (obstructive sleep apnea).
Hydrogeologic conditions and saline-water intrusion, Cape Coral, Florida, 1978-81
Fitzpatrick, D.J.
1986-01-01
The upper limestone unit of the intermediate aquifer system, locally called the upper Hawthorn aquifer, is the principal source of freshwater for Cape Coral, Florida. The aquifer has been contaminated with saline water by downward intrusion from the surficial aquifer system and by upward intrusion from the Floridan aquifer system. Much of the intrusion has occurred through open wellbores where steel casings are short or where casings have collapsed because of corrosion. Saline-water contamination of the upper limestone unit due to downward intrusion from the surficial aquifer is most severe in the southern and eastern parts of Cape Coral; contamination due to upward intrusion has occurred in many areas throughout Cape Coral. Intrusion is amplified in areas of heavy water withdrawals and large water-level declines. (USGS)
NASA Astrophysics Data System (ADS)
Krimi, Mabrouk; Ouaja, Mohamed; Zargouni, Fouad
2017-11-01
The carbonate Zebbag Formation of Upper Albian to Lower Turonian age which outcrops along the Dahar cuestas (south eastern Tunisia) includes several breccia intervals. The stratigraphic hierarchy of these breccia levels led to achieving a detailed sequential analysis within a spectrum of depositional environments extending from subtidal to inner to middle ramp settings. Six major transgressive/regressive sequences make up the stacking of the elementary sequences beginning with transgressive and/or storm wave breccias capped by desiccation and/or collapse breccias. The stratigraphic evolutionary history of the breccia facies are interpreted as the result of the interplay between eustatic and tectonic factors. This model is in accord with the tectonic activities common during Upper Albian-Lower Turonian responsible for the sequences onlapping.
Evolution of Post-accretion-induced Collapse Binaries: The Effect of Evaporation
NASA Astrophysics Data System (ADS)
Liu, Wei-Min; Li, Xiang-Dong
2017-12-01
Accretion-induced collapse (AIC) is widely accepted to be one of the formation channels for millisecond pulsars (MSPs). Since the MSPs have high spin-down luminosities, they can immediately start to evaporate their companion stars after birth. In this paper, we present a detailed investigation on the evolution of the post-AIC binaries, taking into account the effect of evaporation both before and during the Roche-lobe overflow process. We discuss the possible influence of the input parameters including the evaporation efficiency, the initial spin period, and the initial surface magnetic field of the newborn neutron star. We compare the calculated results with the traditional low-mass X-ray binary evolution and suggest that they may reproduce at least part of the observed redbacks and black widows in the companion mass–orbital period plane depending on the mechanisms of angular momentum loss associated with evaporation.
NASA Astrophysics Data System (ADS)
Gregori, Daniel; Benedini, Leonardo
2013-03-01
The Cerro Punta Blanca, Cerro Bayo and Cerro Punta Negra stocks, parts of the Cordillera Frontal Composite Batholith, cropping out in the Cordón del Portillo, records the Gondwana magmatic development of the Cordillera Frontal of Mendoza, in western Argentina. In this area, the San Rafael Orogenic phase, that represents the closure of the Late Carboniferous-Early Permian marine basins, begins at 284 Ma, and ceased before 276 Ma. The Cerro Punta Blanca, Cerro Bayo and Cerro Punta Negra stocks represent a post-orogenic magmatism and are equivalents to the Choiyoi Group. The Gondwana magmatic activity in the Cordón del Portillo area can be divided into two stages. The Cerro Punta Blanca stock (c.a. 276 Ma) represents an early post-orogenic, subduction-related magmatism similar to the basic-intermediate section of the Choiyoi Group (c.a. 277 Ma). The late post-orogenic second event was recorded by the Cerro Bayo (262 Ma) and Cerro Punta Negra stocks which represent a transition between subduction-related and intra-plate magmatism. This event represents the intrusive counterpart of the acidic facies of the upper section of the Choiyoi Group (c.a. 273 Ma). This extensional condition continued during the Triassic when the Cacheuta basin developed.
Prediction of muscle performance during dynamic repetitive movement
NASA Technical Reports Server (NTRS)
Byerly, D. L.; Byerly, K. A.; Sognier, M. A.; Squires, W. G.
2003-01-01
BACKGROUND: During long-duration spaceflight, astronauts experience progressive muscle atrophy and often perform strenuous extravehicular activities. Post-flight, there is a lengthy recovery period with an increased risk for injury. Currently, there is a critical need for an enabling tool to optimize muscle performance and to minimize the risk of injury to astronauts while on-orbit and during post-flight recovery. Consequently, these studies were performed to develop a method to address this need. METHODS: Eight test subjects performed a repetitive dynamic exercise to failure at 65% of their upper torso weight using a Lordex spinal machine. Surface electromyography (SEMG) data was collected from the erector spinae back muscle. The SEMG data was evaluated using a 5th order autoregressive (AR) model and linear regression analysis. RESULTS: The best predictor found was an AR parameter, the mean average magnitude of AR poles, with r = 0.75 and p = 0.03. This parameter can predict performance to failure as early as the second repetition of the exercise. CONCLUSION: A method for predicting human muscle performance early during dynamic repetitive exercise was developed. The capability to predict performance to failure has many potential applications to the space program including evaluating countermeasure effectiveness on-orbit, optimizing post-flight recovery, and potential future real-time monitoring capability during extravehicular activity.
NASA Astrophysics Data System (ADS)
Huang, Chien-Jung; White, Susan; Huang, Shao-Ching; Mallya, Sanjay; Eldredge, Jeff
2016-11-01
Obstructive sleep apnea (OSA) is a medical condition characterized by repetitive partial or complete occlusion of the airway during sleep. The soft tissues in the upper airway of OSA patients are prone to collapse under the low pressure loads incurred during breathing. The ultimate goal of this research is the development of a versatile numerical tool for simulation of air-tissue interactions in the patient specific upper airway geometry. This tool is expected to capture several phenomena, including flow-induced vibration (snoring) and large deformations during airway collapse of the complex airway geometry in respiratory flow conditions. Here, we present our ongoing progress toward this goal. To avoid mesh regeneration, for flow model, a sharp-interface embedded boundary method is used on Cartesian grids for resolving the fluid-structure interface, while for the structural model, a cut-cell finite element method is used. Also, to properly resolve large displacements, non-linear elasticity model is used. The fluid and structure solvers are connected with the strongly coupled iterative algorithm. The parallel computation is achieved with the numerical library PETSc. Some two- and three- dimensional preliminary results are shown to demonstrate the ability of this tool.
JIRICKOVA, A; SULC, J; POHUNEK, P; KITTNAR, O; DOHNALOVA, A; KOFRANEK, J
2009-01-01
Negative expiratory pressure (NEP) applied at the mouth during tidal expiration provides a non-invasive method for detecting expiratory flow limitation. Forty-two children were studied, i.e. 25 children with different respiratory symptoms (R) and 17 without any respiratory symptoms (NR). Children were examined without any sedation. A preset NEP of -5 cm H(2)O was applied; its duration did not exceed duration of tidal expiration. A significance of FL was judged by determining of a flow-limited range (in % of tidal volume). FL was found in 48 % children of R group. No patient of the NR group elicited FL (P<0.001 R vs. NR). The frequency of upper airway collapses was higher in R group (12 children) than in NR group (5 children). In conclusion, a high frequency of tidal FL in the R group was found, while it was not present in NR group. A relatively high frequency of expiratory upper airway collapses was found in both groups, but it did not differ significantly. NEP method represents a reasonable approach for tidal flow limitation testing in non-sedated preschool children.
Sisson, T.W.; Kimura, Jun-Ichi; Coombs, M.L.
2009-01-01
A basanite-nephelinite glass suite from early submarine Kilauea defines a continuous compositional array marked by increasing concentrations of incompatible components with decreasing SiO2, MgO, and Al2O3. Like peripheral and post-shield strongly alkalic Hawaiian localities (Clague et al. in J Volcanol Geotherm Res 151:279-307, 2006; Dixon et al. in J Pet 38:911-939, 1997), the early Kilauea basanite-nephelinite glasses are interpreted as olivine fractionation products from primary magnesian alkalic liquids. For early Kilauea, these were saturated with a garnet-phlogopite-sulfide peridotite assemblage, with elevated dissolved CO2 contents responsible for the liquids' distinctly low-SiO2 concentrations. Reconstructed primitive liquids for early Kilauea and other Hawaiian strongly alkalic localities are similar to experimental 3 GPa low-degree melts of moderately carbonated garnet lherzolite, and estimated parent magma temperatures of 1,350-1,400??C (olivine-liquid geothermometry) match the ambient upper mantle geotherm shortly beneath the base of the lithosphere. The ???3 GPa source regions were too hot for stable crystalline carbonate and may have consisted of ambient upper mantle peridotite containing interstitial carbonate-silicate or carbonatitic liquid, possibly (Dixon et al. in Geochem Geophys Geosyst 9(9):Q09005, 2008), although not necessarily, from the Hawaiian mantle plume. Carbonate-enriched domains were particularly susceptible to further melting upon modest decompression during upward lithospheric flexure beneath the advancing Hawaiian Arch, or by conductive heating or upward drag by the Hawaiian mantle plume. The early Kilauea basanite-nephelinite suite has a HIMU-influenced isotopic character unlike other Hawaiian magmas (Shimizu et al. in EOS Tran Amer Geophys Union 82(47): abstr V12B-0962, 2001; Shimizu et al. in Geochim Cosmochim Acta 66(15A):710, 2002) but consistent with oceanic carbonatite involvement (Hoernle et al. in Contrib Mineral Petrol 142:520-542, 2002). It may represent the melting products of a fertile domain in the ambient upper mantle impinged upon and perturbed by the sustained plume source that feeds later shield-stage magmatism. ?? US Government 2009.
NASA Astrophysics Data System (ADS)
Sisson, T. W.; Kimura, J.-I.; Coombs, M. L.
2009-12-01
A basanite-nephelinite glass suite from early submarine Kilauea defines a continuous compositional array marked by increasing concentrations of incompatible components with decreasing SiO2, MgO, and Al2O3. Like peripheral and post-shield strongly alkalic Hawaiian localities (Clague et al. in J Volcanol Geotherm Res 151:279-307, 2006; Dixon et al. in J Pet 38:911-939, 1997), the early Kilauea basanite-nephelinite glasses are interpreted as olivine fractionation products from primary magnesian alkalic liquids. For early Kilauea, these were saturated with a garnet-phlogopite-sulfide peridotite assemblage, with elevated dissolved CO2 contents responsible for the liquids’ distinctly low-SiO2 concentrations. Reconstructed primitive liquids for early Kilauea and other Hawaiian strongly alkalic localities are similar to experimental 3 GPa low-degree melts of moderately carbonated garnet lherzolite, and estimated parent magma temperatures of 1,350-1,400°C (olivine-liquid geothermometry) match the ambient upper mantle geotherm shortly beneath the base of the lithosphere. The ~3 GPa source regions were too hot for stable crystalline carbonate and may have consisted of ambient upper mantle peridotite containing interstitial carbonate-silicate or carbonatitic liquid, possibly (Dixon et al. in Geochem Geophys Geosyst 9(9):Q09005, 2008), although not necessarily, from the Hawaiian mantle plume. Carbonate-enriched domains were particularly susceptible to further melting upon modest decompression during upward lithospheric flexure beneath the advancing Hawaiian Arch, or by conductive heating or upward drag by the Hawaiian mantle plume. The early Kilauea basanite-nephelinite suite has a HIMU-influenced isotopic character unlike other Hawaiian magmas (Shimizu et al. in EOS Tran Amer Geophys Union 82(47): abstr V12B-0962, 2001; Shimizu et al. in Geochim Cosmochim Acta 66(15A):710, 2002) but consistent with oceanic carbonatite involvement (Hoernle et al. in Contrib Mineral Petrol 142:520-542, 2002). It may represent the melting products of a fertile domain in the ambient upper mantle impinged upon and perturbed by the sustained plume source that feeds later shield-stage magmatism.
Saltzman, B M; Frank, J M; Slikker, W; Fernandez, J J; Cohen, M S; Wysocki, R W
2015-06-01
We conducted a systematic review of studies reporting clinical outcomes after proximal row carpectomy or to four-corner arthrodesis for scaphoid non-union advanced collapse or scapholunate advanced collapse arthritis. Seven studies (Levels I-III; 240 patients, 242 wrists) were evaluated. Significantly different post-operative values were as follows for four-corner arthrodesis versus proximal row carpectomy groups: wrist extension, 39 (SD 11º) versus 43 (SD 11º); wrist flexion, 32 (SD 10º) versus 36 (SD 11º); flexion-extension arc, 62 (SD 14º) versus 75 (SD 10º); radial deviation, 14 (SD 5º) versus 10 (SD 5º); hand grip strength as a percentage of contralateral side, 74% (SD 13) versus 67% (SD 16); overall complication rate, 29% versus 14%. The most common post-operative complications were non-union (grouped incidence, 7%) after four-corner arthrodesis and synovitis and clinically significant oedema (3.1%) after proximal row carpectomy. Radial deviation and post-operative hand grip strength (as a percentage of the contralateral side) were significantly better after four-corner arthrodesis. Four-corner arthrodesis gave significantly greater post-operative radial deviation and grip strength as a percentage of the opposite side. Wrist flexion, extension, and the flexion-extension arc were better after proximal row carpectomy, which also had a lower overall complication rate. © The Author(s) 2014.
THE THREE-DIMENSIONAL EVOLUTION TO CORE COLLAPSE OF A MASSIVE STAR
DOE Office of Scientific and Technical Information (OSTI.GOV)
Couch, Sean M.; Chatzopoulos, Emmanouil; Arnett, W. David
2015-07-20
We present the first three-dimensional (3D) simulation of the final minutes of iron core growth in a massive star, up to and including the point of core gravitational instability and collapse. We capture the development of strong convection driven by violent Si burning in the shell surrounding the iron core. This convective burning builds the iron core to its critical mass and collapse ensues, driven by electron capture and photodisintegration. The non-spherical structure and motion generated by 3D convection is substantial at the point of collapse, with convective speeds of several hundreds of km s{sup −1}. We examine the impactmore » of such physically realistic 3D initial conditions on the core-collapse supernova mechanism using 3D simulations including multispecies neutrino leakage and find that the enhanced post-shock turbulence resulting from 3D progenitor structure aids successful explosions. We conclude that non-spherical progenitor structure should not be ignored, and should have a significant and favorable impact on the likelihood for neutrino-driven explosions. In order to make simulating the 3D collapse of an iron core feasible, we were forced to make approximations to the nuclear network making this effort only a first step toward accurate, self-consistent 3D stellar evolution models of the end states of massive stars.« less
Aftershock collapse vulnerability assessment of reinforced concrete frame structures
Raghunandan, Meera; Liel, Abbie B.; Luco, Nicolas
2015-01-01
In a seismically active region, structures may be subjected to multiple earthquakes, due to mainshock–aftershock phenomena or other sequences, leaving no time for repair or retrofit between the events. This study quantifies the aftershock vulnerability of four modern ductile reinforced concrete (RC) framed buildings in California by conducting incremental dynamic analysis of nonlinear MDOF analytical models. Based on the nonlinear dynamic analysis results, collapse and damage fragility curves are generated for intact and damaged buildings. If the building is not severely damaged in the mainshock, its collapse capacity is unaffected in the aftershock. However, if the building is extensively damaged in the mainshock, there is a significant reduction in its collapse capacity in the aftershock. For example, if an RC frame experiences 4% or more interstory drift in the mainshock, the median capacity to resist aftershock shaking is reduced by about 40%. The study also evaluates the effectiveness of different measures of physical damage observed in the mainshock-damaged buildings for predicting the reduction in collapse capacity of the damaged building in subsequent aftershocks. These physical damage indicators for the building are chosen such that they quantify the qualitative red tagging (unsafe for occupation) criteria employed in post-earthquake evaluation of RC frames. The results indicated that damage indicators related to the drift experienced by the damaged building best predicted the reduced aftershock collapse capacities for these ductile structures.
Ruiz-Eng, Rafael; Montiel-Jarquín, Alvaro; de la Rosa-Pérez, Raúl; López-Colombo, Aurelio; Gómez-Conde, Eduardo; Zamudio-Huerta, Leticia
2010-01-01
Approximately 30% of women who undergo mastectomy without reconstructive treatment due to breast cancer present sequelae. These include paresthesias, keloid healing, hypoesthesia, lymphedema and limitation of the function of the ipsilateral upper extremity. We undertook this study to present the results using collagen-polyvinylpyrrolidone (Clg- Pvp) as treatment for posmastectomy sequelae in women with breast cancer. We conducted a unicentric, longitudinal and prospective clinical trial between August 1, 2007 and July 31, 2008. Included variables were age, lymphedema, limitation of the function of the ipsilateral upper extremity, collapse of the wound, keloid healing, paresthesias, and appearance of the surgical area. The appearance of the surgical area (aesthetic aspect) was evaluated before and 6 months after treatment was initiated. Clg-Pvp was administered weekly for a 6-month period. Seven women were included with a median age of 49 years (range: 40-72 years). One patient (14.28%) presented lymphedema, two patients (28.57%) presented collapse of the wound, two patients (28.57%) had keloid healing, three patients (42.85%) experienced paresthesias, five patients (71.4%) reported pain, and five patients (71.4%) reported limitation of the function of the ipsilateral upper extremity. At the completion of the treatment, aesthetic improvement was statistically significant (p = 0.0020, Mann-Whitney U test). Clinical and aesthetic results are good after application of Clg-Pvp for treating sequelae in women with breast cancer who underwent mastectomy without reconstructive surgery.
Pyroclastic flow deposits on Venus as indicators of renewed magmatic activity
NASA Astrophysics Data System (ADS)
Campbell, Bruce A.; Morgan, Gareth A.; Whitten, Jennifer L.; Carter, Lynn M.; Glaze, Lori S.; Campbell, Donald B.
2017-07-01
Radar bright deposits on Venus that have diffuse margins suggest eruptions that distribute debris over large areas due to ground-hugging flows from plume collapse. We examine deposits in eastern Eistla, western Eistla, Phoebe, and Dione Regiones using Magellan data and Earth-based radar maps. The radar bright units have no marginal lobes or other features consistent with viscous flow. Their morphology, radar echo strength, polarization properties, and microwave emissivity are consistent with mantling deposits composed of few centimeters or larger clasts. This debris traveled downhill up to 100 km on modest slopes and blanketed lava flows and tectonic features to depths of tens of centimeters to a few meters over areas up to 40 × 103 km2. There is evidence for ongoing removal and exhumation of previously buried terrain. A newly identified occurrence is associated with a ridge belt south of Ushas Mons. We also note radar bright streaks of coarse material west of Rona Chasma that reflect the last traces of a deposit mobilized by winds from the formation of Mirabeau crater. If the radar bright units originate by the collapse of eruption columns, with coarse fragmental material entrained and fluidized by hot gases, then their extent suggests large erupted volatile (CO2 or H2O) amounts. We propose that these deposits reflect the early stage of renewed magmatic activity, with volatile-rich, disrupted magma escaping through vents in fractured regions of the upper crust. Rapidly eroding under Venus surface conditions or buried by subsequent eruptions, these markers of recently renewed activity have disappeared from older regions.
Benthic foraminifera at the Cretaceous-Tertiary boundary around the Gulf of Mexico
NASA Astrophysics Data System (ADS)
Alegret, Laia; Molina, Eustoquio; Thomas, Ellen
2001-10-01
Cretaceous-Tertiary (K-T) boundary sections in northeastern Mexico contain marly formations separated by a controversial clastic unit. Benthic foraminifera in seven sections indicate middle and lower bathyal depths of deposition for the marls, with the exception of the upper bathyal northernmost section. Mixed neritic-bathyal faunas were present in the clastic unit, indicating redeposition in the deep basin by mass-wasting processes resulting from the K-T bolide impact in the Gulf of Mexico. Benthic foraminifera in the Mexican sections, and at other deep-sea locations, were not subject to major extinction at the time of impact, but there were temporary changes in assemblage composition. Benthic faunas indicate well- oxygenated bottom waters and mesotrophic conditions during the late Maastrichtian and increased food supply during the latest Maastrichtian. The food supply decreased drastically just after the K-T boundary, possibly because of the collapse of surface productivity. Cretaceous and early Paleogene benthic foraminifera, however, did not exhibit the benthic-pelagic coupling of present-day faunas, as documented by the lack of significant extinction at the K-T collapse of surface productivity. Much of the food supplied to the benthic faunas along this continental margin might have been refractory material transported from land or shallow coastal regions. The decrease in food supply at the K-T boundary might be associated with the processes of mass wasting, which removed surface, food-rich sediment. Benthic faunas show a staggered pattern of faunal recovery in the lowermost Paleogene, consistent with a staged recovery of the vertical organic flux but also with a gradual buildup of organic matter in the sediment.
[Analysis of the causes of failure in surgical treatment of cancer of the larynx].
Semczuk, B; Sekuła, J; Szmeja, Z; Janczewski, G; Kruk-Zagajewska, A; Olszewski, E; Niedzielska, G; Horoch, A; Osuch-Wójcikiewicz, E; Sieradzki, A
1991-01-01
In the years 1985-1990 within the group of 2769 patients operated upon for laryngeal cancer in four medical centres (Kraków, Poznań, Warszawa, Lublin), a clinical analysis on surgical treatment failures was performed. The most significant reasons of failures were: the highly advanced age of patients, coexistent diseases, in particular the cardiopulmonary disease; poor information of neoplastic diseases (carcinomas) and delayed referral to the doctor; lack of consent for surgical treatment; old fashioned diagnostic methods; prolonged period of making diagnosis; increasing number of patients with supra-glottic localization including the hypo-pharynx and piriform recess; a considerable degree of organ ++cancer advancement and substantial clinical advancement; not radical excision of neck glands; intra-surgical blood transfusion; micrometastases to lymphatic glands; immunity collapse; discontinuance of post-surgical radiation on affected parts; lack of lymphadenectomy backward from accessory nerve ; massive cancer metastases to lymph nodes; high histologic malignancy with characteristic carcinous invasiveness; and finally, surgical and post-surgical early and late complications ranginy within our material from 25% to 29% of surgical patients. Basing on the above mentioned analysis, the authors developed indications for surgical treatment of laryngeal cancer.
Two-axis tracker for solar panels and the like
Liao, Henry H.
2013-04-16
A tracker including an outer post having elongated bore and a lower end mounted on a sub-structure, an inner pole rotatably received in the elongated bore, a lower bearing in the bore adjacent a lower end of the outer post and attached thereto to be constrained from lateral movement and mounted on the sub-structure such that a lower end of the inner pole rests on and is supported by the lower bearing, an upper bearing near an upper end of the outer post, a circumferential drive supported on the outer post for rotating the inner pole relative to the outer post, such that substantially a full weight of a load on the inner pole is directly transmitted to the sub-structure and lateral force and torque leverage are placed on a full length of the outer post by way of the upper and lower bearing.
Lee, Minyoung; Lim, Taehyun; Lee, Jaehyuk; Kim, Kimyeong; Yoon, BumChul
2017-11-01
Little is known about the optimal retraining time for regaining functional fitness through multicomponent training following long-term detraining in older adults. This study first investigated the time course of functional fitness changes during 12-month multicomponent training, 12-month detraining, and 9-month retraining in 18 older adults (68.33±3.46) and then determined the optimal retraining time for regaining the post-training functional fitness level after a 12-month detraining period. Functional fitness, including lower and upper limb strength, lower and upper limb flexibility, aerobic endurance, and dynamic balance, was assessed at baseline, 12 months post-training, 12 months post-detraining, and 3, 6, and 9 months post-retraining. There were significant increases in all of the functional fitness components except upper limb flexibility at post-training and no significant decreases at post-detraining. For lower and upper limb strength and lower limb flexibility, a 3-month period was required to regain the post-training condition. For aerobic endurance and dynamic balance, a retraining period ≥9months was necessary to regain the post-training functional fitness condition. To regain the post-training condition of all functional fitness components, a retraining period ≥9months was required. This information might be useful for health professionals to encourage older adults not to interrupt retraining until they regain their post-training functional fitness condition. Copyright © 2017 Elsevier B.V. All rights reserved.
Formation and tectonic evolution of the Pattani Basin, Gulf of Thailand
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bustin, R.M.; Chonchawalit, A.
The stratigraphic and structural evolution of the Pattani Basin, the most prolific petroleum basin in Thailand, reflects the extensional tectonic regime of continental Southeast Asia. E-W extension resulting from the northward collision of India with Eurasia since the Early Tertiary resulted in the formation of a series of N-S-trending sedimentary basins, which include the Pattani Basin. The sedimentary succession in the Pattani Basin is divisible into synrift and postrift sequences. Deposition of the synrift sequence accompanied rifting and extension, with episodic block faulting and rapid subsidence. The synrift sequence comprises three stratigraphic units: (1) Upper Eocene to Lower Olikgocene alluvial-fan,more » braided-river, and floodplain deposits; (2) Upper oligocene to Lowe Miocene floodplain and channel deposits; and (3) a Lower Miocene regressive package consisting of marine to nonmarine sediments. Post-rift succession comprises: (1) a Lower to Middle Miocene regressive package of shallow marine sediments through floodplain and channel deposits; (2) an upper Lower Miocene transgressive sequence; and (3) and Upper Miocene to Pleistocene transgressive succession. The post-rift phase is characterized by slower subsidence and decreased sediment influx. The present-day shallow-marine condition in the Gulf of Thailand is the continuation of this latest transgressive phase. The subsidence and thermal history of the Pattani Basin is consistent with a nonuniform lithospheric-stretching model. The amount of extension as well as surface heat flow generally increases from the margin to the basin center. The crustal stretching factor ({beta}) varies form 1.3 at the basin margin to 2.8 in the center. The subcrustal stretching factor ({delta}) ranges from 1.3 at the basin margin to more than 3.0 in the basin center. 31 refs., 13 figs., 4 tabs.« less
Little, E.E.; Calfee, R.D.; Linder, G.
2014-01-01
The toxicity of five smelter slag-contaminated sediments from the upper Columbia River and metals associated with those slags (cadmium, copper, zinc) was evaluated in 96-h exposures of White Sturgeon (Acipenser transmontanus Richardson, 1836) at 8 and 30 days post-hatch. Leachates prepared from slag-contaminated sediments were evaluated for toxicity. Leachates yielded a maximum aqueous copper concentration of 11.8 μg L−1 observed in sediment collected at Dead Man's Eddy (DME), the sampling site nearest the smelter. All leachates were nonlethal to sturgeon that were 8 day post-hatch (dph), but leachates from three of the five sediments were toxic to fish that were 30 dph, suggesting that the latter life stage is highly vulnerable to metals exposure. Fish maintained consistent and prolonged contact with sediments and did not avoid contaminated sediments when provided a choice between contaminated and uncontaminated sediments. White Sturgeon also failed to avoid aqueous copper (1.5–20 μg L−1). In water-only 96-h exposures of 35 dph sturgeon with the three metals, similar toxicity was observed during exposure to water spiked with copper alone and in combination with cadmium and zinc. Cadmium ranging from 3.2 to 41 μg L−1 or zinc ranging from 21 to 275 μg L−1 was not lethal, but induced adverse behavioral changes including a loss of equilibrium. These results suggest that metals associated with smelter slags may pose an increased exposure risk to early life stage sturgeon if fish occupy areas contaminated by slags.
20. DETAIL OF SOUTH CANTILEVER ANCHOR ARM UPPER CHORD, POST, ...
20. DETAIL OF SOUTH CANTILEVER ANCHOR ARM UPPER CHORD, POST, AND DIAGONAL CONNECTION U-17, LOOKING NORTHWEST - Jackson's Ferry Bridge, Route 52 over New River, 6.3 miles south of Route 94, Austinville, Wythe County, VA
Critical slowing down as early warning for the onset of collapse in mutualistic communities.
Dakos, Vasilis; Bascompte, Jordi
2014-12-09
Tipping points are crossed when small changes in external conditions cause abrupt unexpected responses in the current state of a system. In the case of ecological communities under stress, the risk of approaching a tipping point is unknown, but its stakes are high. Here, we test recently developed critical slowing-down indicators as early-warning signals for detecting the proximity to a potential tipping point in structurally complex ecological communities. We use the structure of 79 empirical mutualistic networks to simulate a scenario of gradual environmental change that leads to an abrupt first extinction event followed by a sequence of species losses until the point of complete community collapse. We find that critical slowing-down indicators derived from time series of biomasses measured at the species and community level signal the proximity to the onset of community collapse. In particular, we identify specialist species as likely the best-indicator species for monitoring the proximity of a community to collapse. In addition, trends in slowing-down indicators are strongly correlated to the timing of species extinctions. This correlation offers a promising way for mapping species resilience and ranking species risk to extinction in a given community. Our findings pave the road for combining theory on tipping points with patterns of network structure that might prove useful for the management of a broad class of ecological networks under global environmental change.
The development of neutrino-driven convection in core-collapse supernovae: 2D vs 3D
NASA Astrophysics Data System (ADS)
Kazeroni, R.; Krueger, B. K.; Guilet, J.; Foglizzo, T.
2017-12-01
A toy model is used to study the non-linear conditions for the development of neutrino-driven convection in the post-shock region of core-collapse supernovae. Our numerical simulations show that a buoyant non-linear perturbation is able to trigger self-sustained convection only in cases where convection is not linearly stabilized by advection. Several arguments proposed to interpret the impact of the dimensionality on global core-collapse supernova simulations are discussed in the light of our model. The influence of the numerical resolution is also addressed. In 3D a strong mixing to small scales induces an increase of the neutrino heating efficiency in a runaway process. This phenomenon is absent in 2D and this may indicate that the tridimensional nature of the hydrodynamics could foster explosions.
NASA Astrophysics Data System (ADS)
Mottyll, S.; Skoda, R.
2015-12-01
A compressible inviscid flow solver with barotropic cavitation model is applied to two different ultrasonic horn set-ups and compared to hydrophone, shadowgraphy as well as erosion test data. The statistical analysis of single collapse events in wall-adjacent flow regions allows the determination of the flow aggressiveness via load collectives (cumulative event rate vs collapse pressure), which show an exponential decrease in agreement to studies on hydrodynamic cavitation [1]. A post-processing projection of event rate and collapse pressure on a reference grid reduces the grid dependency significantly. In order to evaluate the erosion-sensitive areas a statistical analysis of transient wall loads is utilised. Predicted erosion sensitive areas as well as temporal pressure and vapour volume evolution are in good agreement to the experimental data.
Johnson, James H.; Farquhar, James F.; Klindt, Rodger M; Mazzocchi, Irene; Mathers, Alastair
2015-01-01
The number of double-crested cormorants (Phalacrocorax auritus) in the upper St. Lawrence River has increased markedly since the early 1990s. In 1999, a binational study was initiated to examine the annual diet composition and fish consumption of cormorants at colonies in the upper river. Since 1999, 14,032 cormorant pellets, collected from May through September each year, have been examined from St. Lawrence River colonies to estimate fish consumption and determine temporal and spatial variation in diet. Seasonal variation in diet composition within a colony was low. Prior to 2006 yellow perch was the primary fish consumed by cormorants in the upper St. Lawrence River. Round goby were first observed in cormorant diets in 2003 and by 2006 were the main fish consumed at two of the three colonies. The time interval it took from the first appearance of round goby in the diet at a colony to when goby were the dominant prey species varied by island, ranging from two to five years. Daily fish consumption at each cormorant colony increased significantly from the pre-round goby to post-round goby period. The mean annual biomass of yellow perch consumed decreased significantly during the post-round goby period at the three colonies. Reduced consumption of yellow perch by cormorants may alleviate suspected localized impacts on perch near some of the larger river colonies.
NASA Astrophysics Data System (ADS)
Commerçon, B.; Hennebelle, P.; Levrier, F.; Launhardt, R.; Henning, Th.
2012-03-01
I will present radiation-magneto-hydrodynamics calculations of low-mass and massive dense core collapse, focusing on the first collapse and the first hydrostatic core (first Larson core) formation. The influence of magnetic field and initial mass on the fragmentation properties will be investigated. In the first part reporting low mass dense core collapse calculations, synthetic observations of spectral energy distributions will be derived, as well as classical observational quantities such as bolometric temperature and luminosity. I will show how the dust continuum can help to target first hydrostatic cores and to state about the nature of VeLLOs. Last, I will present synthetic ALMA observation predictions of first hydrostatic cores which may give an answer, if not definitive, to the fragmentation issue at the early Class 0 stage. In the second part, I will report the results of radiation-magneto-hydrodynamics calculations in the context of high mass star formation, using for the first time a self-consistent model for photon emission (i.e. via thermal emission and in radiative shocks) and with the high resolution necessary to resolve properly magnetic braking effects and radiative shocks on scales <100 AU (Commercon, Hennebelle & Henning ApJL 2011). In this study, we investigate the combined effects of magnetic field, turbulence, and radiative transfer on the early phases of the collapse and the fragmentation of massive dense cores (M=100 M_⊙). We identify a new mechanism that inhibits initial fragmentation of massive dense cores, where magnetic field and radiative transfer interplay. We show that this interplay becomes stronger as the magnetic field strength increases. We speculate that highly magnetized massive dense cores are good candidates for isolated massive star formation, while moderately magnetized massive dense cores are more appropriate to form OB associations or small star clusters. Finally we will also present synthetic observations of these collapsing massive dense cores.
NASA Astrophysics Data System (ADS)
Petsios, E.; Bottjer, D. J.
2016-12-01
The Permian-Triassic mass extinction, the largest extinction of the Phanerozoic, is attributed to volcanic outgassing from the Siberian Traps and the resulting climate change. Ongoing volcanism in the Early Triassic is implicated for continued carbon cycle instability following the initial event, reflected in large inorganic carbon isotope excursions throughout the 5 Mya interval. Recent paleoecological studies have shown that timing of recovery from the extinction in the Early Triassic is highly complex, differing between regions, with documented cases of "early" recovery in some environments. The importance of specific environmental factors, such as oxygen levels and sea surface temperatures, in aiding or hindering recovery following the extinction is the topic of ongoing study. Here we present an ecological survey of marine benthic communities from the Lower Triassic Blacktail Creek outcrop of the Dinwoody Formation, correlated bed-for-bed with inorganic carbon isotope values. We observe incipient recovery as communities show increasing richness and evenness throughout the section, followed by a `collapse' with a return of high dominance, low richness fauna coincident with large δ13Ccarb shifts. We observe a statistically significant correlation between the magnitude of δ13Ccarb excursions and benthic community complexity over a stratigraphic section, implying a shared causal mechanism acting at the local scale. The globally correlatable nature of these observed carbon isotope shifts, as well as an absence of lithologic evidence for oxygen limitation, points to thermal stress brought on by pulses of volcanism as the shared cause between recovery collapse and carbon cycle perturbations. We propose that the "early" recovery at Blacktail Creek was truncated by recurrent greenhouse gas induced thermal spikes, highlighting the interplay of local and global environmental conditions in expediting or hindering Early Triassic recovery.
Outcome of patients in laparoscopic training courses compared to standard patients.
Kanakala, V; Bawa, S; Gallagher, P; Woodcock, S; Attwood, S E; Horgan, L F; Seymour, K
2010-06-01
Current Laparoscopic simulators have limited usefulness and patients have been used for training since the dawn of surgery. NUGITS (Northumbrian Upper Gastro Intestinal Team of Surgeons) Laparoscopic Skills courses utilise hands-on experience with simulators moving to live operating on volunteer patients. It is vital to know that the volunteer patient is not disadvantaged by greater surgical risk. This was a case-controlled prospective comparison of patients undergoing both Laparoscopic Cholecystectomy (LC) [n=51] and Laparoscopic Inguinal Hernia (LIH) [n=62] during NUGITS training courses. They are compared with a matched (age, sex and ASA grade) control group LC (n=51) and LIH (n=62) operated on by consultants. The outcome measures were surgical peri-and post-operative complications, post-operative hospital stay, readmission and early recurrence of inguinal hernia (<6 months). In the LC cohort, there was no significant difference in the length of hospital stay (p=0.07) or readmission (p=0.16) in both the groups. The mean operating time was higher in the trainee compared to the control group (p=0.001). There was no difference in the post-operative morbidity or mortality in either group. In LIH cohort, the mean operating time was higher in the trainee compared with the control group. There was no significant difference in post-operative complications (p>0.05) and early post-operative recurrence of hernia (p>0.05). The post-operative outcomes of patients undergoing laparoscopic surgery during laparoscopic training courses are similar to consultant-operated patients. Thus, it is acceptable and safe to encourage patients to volunteer for laparoscopic training courses. Copyright (c) 2009 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.
Understanding restoration of Oregon's Wood River through multi-modal hydrogeomorphic monitoring
NASA Astrophysics Data System (ADS)
Dearman, T.; Hughes, M. L.
2017-12-01
Channelized reaches of the lower Wood River in the Upper Klamath Basin of Oregon have undergone extensive restoration since the late 1990's, when the Bureau of Land Management began managing for the benefit of redband trout and other native-endemic species. Restoration included reconstruction of a floodplain and channel meanders, narrowing and deepening of channel, and excavation and reoccupation of fluvio-deltaic channels connecting the river to the Upper Klamath-Agency Lake system. The goals of this study were to extend the restoration monitoring record and evaluate post-restoration performance in light of this record. Monitoring included channel-bathymetry mapping, measurements of sediment transport (bedload), and measurement of discharge at points throughout the project reach under differing stage conditions. Results indicate two distinct domains of channel response to restoration: (1) an upstream domain marked by aggradation in the early and incision in the late post-restoration periods, and (2) a downstream domain marked by the inverse responses of degradation in the early and aggradation in the late post-restoration periods. These domains are separated by the confluence of an artificial channel maintained for boating access. Flow and sediment-transport continuity are interrupted at this confluence. At high stage (winter/spring) impoundment from the lake stalls flow, inducing sediment deposition. Stage falls as lake level recedes in the summer and stream power is restored, thereby releasing the sediment trapped at high stage. Aggradation in the downstream domain coupled with excavation of a birdfoot distributary in 2010 combined to initiate an avulsion from one distributary to another during the 2015 flow recession. With the exception of this recent avulsion, monitoring data suggest the channel system is approaching a dynamic equilibrium and behaving consistently with the rate law in geomorphology. This study provides the first known synthesis of long-term geomorphic monitoring of a freshwater fluvio-deltaic channel restoration in the Pacific Northwest.
NASA Astrophysics Data System (ADS)
Pearle, Philip
2007-03-01
In this volume in honour of GianCarlo Ghirardi, I discuss my involvement with ideas of dynamical collapse of the state vector. Ten problems are introduced, nine of which were seen following my initial work. Four of these problems had a resolution in GianCarlo Ghirardi, Alberto Rimini and Tullio Weber's spontaneous localization (SL) model (which added one more problem). This stimulated a (somewhat different) resolution of these five problems in the continuous spontaneous localization (CSL) model, in which I combined my initial work with SL. In an upcoming volume in honour of Abner Shimony, I shall discuss the status of the remaining five post-CSL problems.
Wallace, Adam N; Vyhmeister, Ross; Hsi, Andy C; Robinson, Clifford G; Chang, Randy O; Jennings, Jack W
2015-12-01
Stereotactic radiosurgery and percutaneous radiofrequency ablation are emerging therapies for pain palliation and local control of spinal metastases. However, the post-treatment imaging findings are not well characterized and the risk of long-term complications is unknown. We present the case of a 46-year-old woman with delayed vertebral body collapse after stereotactic radiosurgery and radiofrequency ablation of a painful lumbar metastasis. Histopathologic-MRI correlation confirmed osteonecrosis as the underlying etiology and demonstrated that treatment-induced vascular fibrosis and tumor progression can have identical imaging appearances. © The Author(s) 2015.
Modelling physiological deterioration in post-operative patient vital-sign data.
Pimentel, Marco A F; Clifton, David A; Clifton, Lei; Watkinson, Peter J; Tarassenko, Lionel
2013-08-01
Patients who undergo upper-gastrointestinal surgery have a high incidence of post-operative complications, often requiring admission to the intensive care unit several days after surgery. A dataset comprising observational vital-sign data from 171 post-operative patients taking part in a two-phase clinical trial at the Oxford Cancer Centre, was used to explore the trajectory of patients' vital-sign changes during their stay in the post-operative ward using both univariate and multivariate analyses. A model of normality based vital-sign data from patients who had a "normal" recovery was constructed using a kernel density estimate, and tested with "abnormal" data from patients who deteriorated sufficiently to be re-admitted to the intensive care unit. The vital-sign distributions from "normal" patients were found to vary over time from admission to the post-operative ward to their discharge home, but no significant changes in their distributions were observed from halfway through their stay on the ward to the time of discharge. The model of normality identified patient deterioration when tested with unseen "abnormal" data, suggesting that such techniques may be used to provide early warning of adverse physiological events.
NASA Astrophysics Data System (ADS)
Kuroda, Takami; Kotake, Kei; Takiwaki, Tomoya; Thielemann, Friedrich-Karl
2018-06-01
We study the final fate of a very massive star by performing full general relativistic (GR), three-dimensional (3D) simulation with three-flavour multi-energy neutrino transport. Utilizing a 70 solar mass zero-metallicity progenitor, we self-consistently follow the radiation-hydrodynamics from the onset of gravitational core-collapse until the second collapse of the proto-neutron star (PNS), leading to black hole (BH) formation. Our results show that the BH formation occurs at a post-bounce time of Tpb ˜ 300 ms for the 70 M⊙ star. This is significantly earlier than those in the literature where lower mass progenitors were employed. At a few ˜10 ms before BH formation, we find that the stalled bounce shock is revived by intense neutrino heating from the very hot PNS, which is aided by violent convection behind the shock. In the context of 3D-GR core-collapse modelling with multi-energy neutrino transport, our numerical results present the first evidence to validate a fallback BH formation scenario of the 70 M⊙ star.
Virginia Space Grant Consortium Upper Atmospheric Payload Balloon System (Vps)
NASA Technical Reports Server (NTRS)
Marz, Bryan E.; Ash, Robert L.
1996-01-01
This document provides a summary of the launch and post-launch activities of Virginia Space Grant Consortium Upper Atmospheric Payload Balloon System, V(ps). It is a comprehensive overview covering launch activities, post-launch activities, experimental results, and future flight recommendations.
Adult obstructive sleep apnoea
Jordan, Amy S.; McSharry, David G.; Malhotra, Atul
2013-01-01
Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway collapse during sleep, which leads to oxygen desaturation and disrupted sleep. Symptoms include snoring, witnessed apnoeas, and sleepiness. Pathogenesis varies; predisposing factors include small upper airway lumen, unstable respiratory control, low arousal threshold, small lung volume, and dysfunctional upper airway dilator muscles. Risk factors include obesity, male sex, age, menopause, fluid retention, adenotonsillar hypertrophy, and smoking. Obstructive sleep apnoea causes sleepiness, road traffic accidents, and probably systemic hypertension. It has also been linked to myocardial infarction, congestive heart failure, stroke, and diabetes mellitus though not definitively. Continuous positive airway pressure is the treatment of choice, with adherence of 60–70%. Bi-level positive airway pressure or adaptive servo-ventilation can be used for patients who are intolerant to continuous positive airway pressure. Other treatments include dental devices, surgery, and weight loss. PMID:23910433
TOP VIEW OF UPPER TRAM TERMINAL, PRIMARY ORE BIN, AND ...
TOP VIEW OF UPPER TRAM TERMINAL, PRIMARY ORE BIN, AND ORE CHUTE,LOOKING SOUTHWEST. TRAM MACHINERY AND GEARS ARE AT LOWER CENTER. A SMALL ELECTRIC MOTOR AT THE REAR LEFT OF THE TERMINAL PROBABLY WAS ADDED AFTER THE ORIGINAL CONSTRUCTION. THE MOVING CABLE OF THE TRAM WAS DRIVEN BY THESE GEARS AND THE LARGE WHEEL UNDERNEATH (SEE CA-291-31 FOR DETAIL). EMPTY TRAM BUCKETS CAME IN FROM THE LEFT, SWINGING AROUND TO THE CHUTES FROM THE ORE BIN TO BE LOADED FOR THE TRIP DOWN TO THE MILL (SEE CA-291-35 FOR DETAIL). THE BREAK OVER TOWER CAN BE SEEN IN THE DISTANCE AT TOP LEFT. THE SUPPORT TOWER BETWEEN THE UPPER TERMINAL AND THE BREAK OVER TOWER IS COLLAPSED. - Keane Wonder Mine, Park Route 4 (Daylight Pass Cutoff), Death Valley Junction, Inyo County, CA
The Role of CO2 Clouds on the Stability of the Early Mars Atmosphere Against Collapse
NASA Astrophysics Data System (ADS)
Kahre, Melinda A.; Haberle, Robert; Steakley, Kathryn; Murphy, Jim; Kling, Alexandre
2017-10-01
The early Mars atmosphere was likely significantly more massive than it is today, given the growing body of evidence that liquid water flowed on the surface early in the planet’s history. Although the CO2 inventory was likely larger in the past, there is much we still do not understand about the state of that CO2. As surface pressure increases, the temperature at which CO2 condenses also increases, making it more likely that CO2 ice would form and persist on the surface when the atmospheric mass increases. An atmosphere that is stable against collapse must contain enough energy, distributed globally, to prohibit the formation of permanents CO2 ice reservoirs that lead to collapse. The presence of the “faint young sun” compounds this issue. Previous global climate model (GCM) investigations show that atmospheres within specific ranges of obliquities and atmospheric masses are stable against collapse. We use the NASA Ames Mars GCM to expand on these works by focusing specifically on the role of CO2 clouds in atmospheric stability. Two end member simulations are executed, one that includes CO2 cloud formation and one that does not. The simulation that explicitly includes CO2 clouds is stable, while the simulation without CO2 clouds collapses into permanent surface CO2 reservoirs. In both cases, significant atmospheric condensation is occurring in the atmosphere throughout the year. In the case without CO2 clouds, all atmospheric condensation (even if it occurs at altitude) leads directly to the accumulation of surface ice, whereas in the case with CO2 clouds, there is a finite settling timescale for the cloud particles. Depending on this timescale and the local conditions, the cloud particles could stay aloft or sublimate as they fall toward the surface. Thus, the striking difference between these two cases illustrates the important role of CO2 clouds. We plan to conduct and present further simulations to better understand how atmospheric stability depends on the details of CO2 cloud microphysical processes and assumptions.
Abeyasinghe, N L; de Zoysa, P; Bandara, K M K C; Bartholameuz, N A; Bandara, J M U J
2012-01-01
Post-Traumatic Stress Disorder has been identified as one of the most commonly occurring mental illnesses in combatants. This study was conducted to determine the prevalence of Post-Traumatic Stress Disorder among soldiers who had undergone amputation of a lower or an upper limb or sustained a spinal cord injury in the battlefield, and to compare the prevalence among these categories. The research presented seeks to increase the awareness of this condition among those treating war casualties so that appropriate treatment choices could be made to address them. The study was carried out in 2009 at a rehabilitation centre for combatants of war. Data were collected from 96 male army veterans between the ages of 18-49 years using a pre-tested self-administered questionnaire based on the Diagnostic and Statistical Manual of Mental Disorders, the Impact of Event Scale and the PTSD symptom scale. Soldiers with injuries sustained at least four weeks prior to the study were selected by a convenience sampling technique. Soldiers with multiple injuries, head injuries or those diagnosed with psychiatric disorders were excluded. The results revealed that 41.7% of the study population was compatible with the diagnosis of Post-Traumatic Stress Disorder. Within the three groups, 42.5% of the lower limb amputees, 33.3% of the upper limb amputees and 45.7% of the participants with spinal cord injury had symptoms compatible with Post-Traumatic Stress Disorder. There was no difference between the prevalence among the different injury categories considered. This study highlights the need to pay more attention in providing psychological care as a part of the overall health management of injured combatants. Early preparation of soldiers for stressors of war and screening for and proper management of Post-Traumatic Stress Disorder will improve the overall outcome of rehabilitation.
How Thin Is the Ice?: The Potential for Collapse in Today’s Army
2010-05-21
Army now skates ? An examination of some historical examples of military collapse leads to the conclusion that early warnings are frequently seen...have voiced concerns about impact of sustained combat operations on the Army. How thin, really, is the ice upon the U.S. Army now skates ? An...have voiced concerns about the impact of sustained combat operations on the Army. How thin, really, is the ice upon the U.S. Army now skates ? The
Mega-geomorphology: Mars vis a vis Earth
NASA Technical Reports Server (NTRS)
Sharp, R. P.
1985-01-01
The areas of chaotic terrain, the giant chasma of the Valles Marineris region, the complex linear and circular depressions of Labyrinthus Noctis on Mars all suggest the possibility of large scale collapse of parts of the martian crust within equatorial and sub equatorial latitudes. It seems generally accepted that the above features are fossil, being perhaps, more than a billion years old. It is possible that parts of Earth's crust experienced similar episodes of large scale collapse sometime early in the evolution of the planet.
Taylor, Susan; Shmon, Cindy; Su, Lillian; Epp, Tasha; Minor, Katie; Mickelson, James; Patterson, Edward; Shelton, G Diane
2016-01-01
Clinical and metabolic variables were evaluated in 13 dogs with border collie collapse (BCC) before, during, and following completion of standardized strenuous exercise protocols. Six dogs participated in a ball-retrieving protocol, and seven dogs participated in a sheep-herding protocol. Findings were compared with 16 normal border collies participating in the same exercise protocols (11 retrieving, five herding). Twelve dogs with BCC developed abnormal mentation and/or an abnormal gait during evaluation. All dogs had post-exercise elevations in rectal temperature, pulse rate, arterial blood pH, PaO2, and lactate, and decreased PaCO2 and bicarbonate, as expected with strenuous exercise, but there were no significant differences between BCC dogs and normal dogs. Electrocardiography demonstrated sinus tachycardia in all dogs following exercise. Needle electromyography was normal, and evaluation of muscle biopsy cryosections using a standard panel of histochemical stains and reactions did not reveal a reason for collapse in 10 dogs with BCC in which these tests were performed. Genetic testing excluded the dynamin-1 related exercise-induced collapse mutation and the V547A malignant hyperthermia mutation as the cause of BCC. Common reasons for exercise intolerance were eliminated. Although a genetic basis is suspected, the cause of collapse in BCC was not determined.
Influence of Non-spherical Initial Stellar Structure on the Core-Collapse Supernova Mechanism
NASA Astrophysics Data System (ADS)
Couch, Sean M.
I review the state of investigation into the impact that nonspherical stellar progenitor structure has on the core-collapse supernova mechanism. Although modeling stellar evolution relies on 1D spherically symmetric calculations, massive stars are not truly spherical. In the stellar evolution codes, this fact is accounted for by "fixes" such as mixing length theory and attendant modifications. Of particular relevance to the supernova mechanism, the Si- and O-burning shells surrounding the iron core at the point of collapse can be violently convective, with convective speeds of hundreds of km s-1. It has recently been shown by a number of groups that the presence of nonspherical perturbations in the layers surrounding the collapsing iron core can have a favorable impact on the likelihood for shock revival and explosion via the neutrino heating mechanism. This is due in large part to the strengthening of turbulence behind the stalled shock due to the presence of finite amplitude seed perturbations to speed the growth of convection which drives the post-shock turbulence. Efforts are now underway to simulate the final minutes of stellar evolution to core-collapse in 3D with the aim to generate realistic multidimensional initial conditions for use in simulations of the supernova mechanism.
NASA Astrophysics Data System (ADS)
Duperret, A.; Genter, A.; Daigneault, M.; Mortimore, R. N.
Coastal chalk cliffs exposed on each part of the English Channel suffer numerous collapses, with mean volumes varying between 10 000 and 100 000 cubic meters. Between October 1998 and October 2001, a minimum of 52 collapses have been ob- served along 120 km of the French chalk coastline located in Upper-Normandy and Picardy. The chalk coastline has evidenced 4 collapses in 1999 and 6 collapses in 2000 (winter and spring), whereas 28 collapses with volume greater than 1000 m3 was recorded in 2001 (winter, spring and summer). The increase of large-scale collapses during 2001 is interpreted as an excess of rainfalls recorded previously. Most of these collapses extend all over the vertical cliff height and are mainly controlled by ground- water infiltration. The modality of water circulation through the chalk rock depends on the chalk lithology and the hydrogeological properties of pre-existing fractures. In the framework of the European scientific project named ROCC (Risk of Cliff Col- lapse), the chalk lithology and the pre-existing fracture pattern have been investigated in order to determine the response of the rock mass to subaerial and marine solicita- tions, including rainfall conditions. Such data have been reported in a GIS system in order to determine the degree of cliff sensibility to collapses. Some rainfall-triggered collapses will be presented to illustrate the diversity of the rock mass response to rain- fall excess, in terms of rock mass characteristics and time delay: (1) a collapse was witnessed at Puys, the 17th May 2000, after two periods of intense rainfall inducing floods, during the two previous months. The occurrence of impervious marl seams levels within the chalk and its low fracture content may have generated water over- pressure and consequently stress concentration on the marl seams, which conduct to the rupture. The delay between rainfall and the rupture may be explained by the low velocity of groundwater through a poorly fractured porous chalk. (2) a series of large- scale collapses has been evidenced at Yport in June 2001, at Grandes Dalles the 15th July 2001 and at Benouville the 24th July 2001. These collapses occurred after a dry period, during the previous three months. A collapse occurred again at Yport the 27th August 2001, after an increase of rainfall during August 2001. All these sites present the same lithological chalk succession than at Puys, but their fracture pattern is made of large-scale subvertical fractures expanding all over the cliff height. Some of them 1 which correspond to dissolution pipes are filled with clays-with-flints. The sharp in- crease of collapses during the summer 2001 could be related to the superimposition of dry periods which alternate with heavy rainfalls, in karst environment. 2
Wang, X; Zhang, J J; Yuan, F S; Wang, Y; Li, C H; Varrela, J E; Yue, J; Ge, L H
2018-06-18
To investigate the clinical effect of eruption guidance appliance in the treatment of anterior cross bite in mixed-dentition children. In the study,10 mixed-dentition children with anterior cross bite, totally 12 incisors, were selected. Alginate was used to take upper and lower dentition impression and make a hard plaster model,which served as the eruption guidance appliance for treatment. The pre- and post-operative dental casts were digitized with SmartOptics Activity 880 scanner,and the three-dimensional overlapping models were obtained by reverse engineering software,Geomagic Studio 2012,then the three-dimensional movements of the upper and lower incisors were analyzed using Imageware 13.2 software. The overbite and overjet were analyzed using the same methods. Measurement with copper wire was used to analyze the upper and lower arch length. Space analysis was the result by the sum of crown width minus the arch length. The crown width of unerupted permanent teeth was according to X-ray method to predict. The SPSS 17.0 software was used to analyze the pre- and post-operative measurements of the same child. The normality test of the measured data showed that it conformed to the normal distribution. Therefore,the t test and double side test were used,and the significance level was 0.05. The course of treatment was (5.6±2.7) months. During orthodontic treatment, the upper incisors moved mainly labially (P<0.001) in three-dimensional displacement, and the lower incisors moved mainly the same direction (P=0.025). During the treatment of eruption guidance appliance,the average overbite decreased (1.01±0.9) mm (t=-3.531, P=0.006), and the difference was statistically significant. There was no statistically significant difference between the pre- and post-operative average overjet (t=0.771, P=0.460). The severity of crowding in upper arch decreased (1.9±0.99) mm (t=-6.042, P<0.001),and that in lower arch decreased (1.9±0.74) mm (t=-8.143, P<0.001), both of the differences were statistically significant. The anterior cross bite in mixed dentition could be corrected by eruption guidance appliance, and at the same time, the normal overjet and overbite were established, and the teeth were aligned.
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging.
Ben-Zvi, Anat; Miller, Elizabeth A; Morimoto, Richard I
2009-09-01
Protein damage contributes prominently to cellular aging. To address whether this occurs at a specific period during aging or accumulates gradually, we monitored the biochemical, cellular, and physiological properties of folding sensors expressed in different tissues of C. elegans. We observed the age-dependent misfolding and loss of function of diverse proteins harboring temperature-sensitive missense mutations in all somatic tissues at the permissive condition. This widespread failure in proteostasis occurs rapidly at an early stage of adulthood, and coincides with a severely reduced activation of the cytoprotective heat shock response and the unfolded protein response. Enhancing stress responsive factors HSF-1 or DAF-16 suppresses misfolding of these metastable folding sensors and restores the ability of the cell to maintain a functional proteome. This suggests that a compromise in the regulation of proteostatic stress responses occurs early in adulthood and tips the balance between the load of damaged proteins and the proteostasis machinery. We propose that the collapse of proteostasis represents an early molecular event of aging that amplifies protein damage in age-associated diseases of protein conformation.
NASA Astrophysics Data System (ADS)
Yusufoğlu, H.
2013-04-01
The Elbistan Basin in the east-Central Anatolia is an intramontane structural depression in the interior part of the Anatolide-Tauride Platform. The Neogene fill in and around Elbistan Basin develops above the Upper Devonian to lower Tertiary basement and comprises two units separated by an angular unconformity: (1) intensely folded and faulted Miocene shallow marine to terrestrial and lacustrine sediments and (2) nearly flat-lying lignite-bearing lacustrine (lower unit) and fluvial (upper unit) deposits of Plio-Quaternary Ahmetçik Formation. The former is composed of Lower-Middle Miocene Salyan, Middle-upper Middle Miocene Gövdelidağ and Upper Miocene Karamağara formations whereas the latter one is the infill of the basin itself in the present configuration of the Elbistan Basin. The basin is bound by normal faults with a minor strike-slip component. It commenced as an intramontane pull-apart basin and developed as a natural response to Early Pliocene tectonic escape-related strike-slip faulting subsequent to post-collisional intracontinental compressional tectonics during which Miocene sediments were intensely deformed. The Early Pliocene time therefore marks a dramatic changeover in tectonic regime and is interpreted as the beginning of the ongoing last tectonic evolution and deformation style in the region unlike to previous views that it commenced before that time. Consequently, the Elbistan Basin is a unique structural depression that equates the extensional strike-slip regime in east-Central Anatolia throughout the context of the neotectonical framework of Turkey across progressive collision of Arabia with Eurasia. Its Pliocene and younger history differs from and contrasts with that of the surrounding pre-Pliocene basins such as Karamağara Basin, on which it has been structurally superimposed.
Himalayan Sackung and Associations to Regional Structure
NASA Astrophysics Data System (ADS)
Shroder, J. F.; Bishop, M. P.; Olsenholler, J.
2003-12-01
Recognition of sackung slope failure or deep-seated, rock-slope deformation in the Himalaya has been rather limited, in part because: (1) many geoscientists do not recognize its characteristics; (2) large-scale aerial photographs and topographic maps used to identify the characteristic surficial, topographic manifestations of the failure type are commonly low-level state secrets in that region; and (3) no systematic survey for sackung has ever been made in the Himalaya. In the Pakistani-controlled, western Himalaya, some unconventional access to aerial photographs in the Kaghan and Nanga Parbat areas allowed first recognition of several characteristic ridge-top grabens and anti-slope scarps. Later release of declassified, stereo imagery from the CORONA and KEYHOLE satellite series enabled discovery of other examples in the K2 region. Comparison of mapped sackung failures with geologic base maps has demonstrated some coincidence of sackung with various structural trends, including synformal structures in upper thrust plates or along the traces of high-angle faults. In all probability these structural trends have provided plentiful ancillary planes of weakness along which gravitationally driven sackung is facilitated. Sackung failure in the Himalaya appears to be a spatially scale-dependent manifestation of a gravitational-collapse continuum of the brittle, upper crust, mainly involving mountain ridges. In contrast, gravitational collapse of the whole range may involve some similar failures but also include listric faulting, as well as subsidence movement into zones of ductility at depth. Temporal scale dependence of sackung may also be threshold dominated, wherein initial long-continued, slow failure ultimately leads to the commonly catastrophic rock-slope collapses recently recognized throughout the western Himalaya and now differentiated from their original mismapping as glacial moraines. Such sackung in Himalayan terrain undergoing active deglaciation from global warming may increase catastrophic slope-failure hazard.
Anatomic Optical Coherence Tomography of Upper Airways
NASA Astrophysics Data System (ADS)
Chin Loy, Anthony; Jing, Joseph; Zhang, Jun; Wang, Yong; Elghobashi, Said; Chen, Zhongping; Wong, Brian J. F.
The upper airway is a complex and intricate system responsible for respiration, phonation, and deglutition. Obstruction of the upper airways afflicts an estimated 12-18 million Americans. Pharyngeal size and shape are important factors in the pathogenesis of airway obstructions. In addition, nocturnal loss in pharyngeal muscular tone combined with high pharyngeal resistance can lead to collapse of the airway and periodic partial or complete upper airway obstruction. Anatomical optical coherence tomography (OCT) has the potential to provide high-speed three-dimensional tomographic images of the airway lumen without the use of ionizing radiation. In this chapter we describe the methods behind endoscopic OCT imaging and processing to generate full three dimensional anatomical models of the human airway which can be used in conjunction with numerical simulation methods to assess areas of airway obstruction. Combining this structural information with flow dynamic simulations, we can better estimate the site and causes of airway obstruction and better select and design surgery for patients with obstructive sleep apnea.
Park, J-H; Kang, K-C; Shin, D-E; Koh, Y-G; Son, J-S; Kim, B-H
2014-02-01
The progression of fractured vertebral collapse is not rare after a conservative treatment of vertebral compression fracture (VCF). Teriparatide has been shown to directly stimulate bone formation and improve bone density, but there is a lack of evidence regarding its use in fracture management. Conservative treatment with short-term teriparatide is effective for decreasing the progression of fractured vertebral body collapse. Few studies have reported on the prevention of collapsed vertebral body progression after osteoporotic VCF. Teriparatide rapidly enhances bone formation and increases bone strength. This study evaluated preventive effects of short-term teriparatide on the progression of vertebral body collapse after osteoporotic VCF. Radiographs of 68 women with single-level osteoporotic VCF at thoracolumbar junction (T11-L2) were reviewed. Among them, 32 patients were treated conservatively with teriparatide (minimum 3 months) (group I), and 36 were treated with antiresorptive (group II). We measured kyphosis and wedge angle of the fractured vertebral body, and ratios of anterior, middle, and posterior heights of the collapsed body to posterior height of a normal upper vertebra were determined. The degree of collapse progression was compared between two groups. The progression of fractured vertebral body collapse was shown in both groups, but the degree of progression was significantly lower in group I than in group II. At the last follow-up, mean increments of kyphosis and wedge angle were significantly lower in group I (4.0° ± 4.2° and 3.6° ± 3.6°) than in group II (6.8° ± 4.1° and 5.8° ± 3.5°) (p = 0.032 and p = 0.037). Decrement percentages of anterior and middle border height were significantly lower in group I (9.6 ± 10.3 and 7.4 ± 7.5 %) than in group II (18.1 ± 9.7 and 13.8 ± 12.2 %) (p = 0.001 and p = 0.025), but not in posterior height (p = 0.086). In female patients with single-level osteoporotic VCF at the thoracolumbar junction, short-term teriparatide treatment did not prevent but did decrease the progression of fractured vertebral body collapse.
NASA Astrophysics Data System (ADS)
Callot, Pierre; Odonne, Francis; Sempere, Thierry
2008-12-01
In the back-arc basin of southern Peru, the bulk of the mid-Cretaceous carbonate platform collapsed near the Turonian-Coniacian boundary (~ 90-89 Ma), due to slope creation and resulting oversteepening. The resulting mass-wasting deposits, namely the Ayabacas Formation, consist of a megabreccia which is organised from NE to SW in relation with two major fault systems. Facies of sediment reworking (such as brecciation, liquification, sedimentary dykes and soft-sediment deformation) are described and four types of resedimentation facies are define. In the northeastern part of the study area, deposits mainly consist of a mixture of very heterometric clasts and blocks (millimetric to kilometric in size), mainly carbonate but also sandy-marly in nature, floating in sandy-marly matrix that exhibits features of liquification (sedimentary dykes and flows) and plastic deformation. Here, resedimentation facies are characterized by deformations and a brecciated facies at each observation scale (from aerial photographs to thin sections) and are therefore defined as fractal or multi-scale breccias. Some clasts and large amounts of the matrix were derived from the underlying clay-rich sandstones of the Murco Formation. These materials were prone to liquification and plastic deformation, allowing them to act as a sliding sole that facilitated the slides and the downslope movement of large limestone rafts. In the southwestern part of the study area, only limestone breccias are observed, in alternation with well-stratified levels. The sliding sole of plastically deformable siliciclastic sediments that previously acted as a lubricating layer was not present here, as materials were more deeply buried. Variations in the degree of sediment lithification from northeast to southwest are inferred to have existed before the collapse and also within the sedimentary succession in the northeastern part. In particular, limestones were well-cemented at the base of the carbonate succession and formed a cap that prevented water to escape from the underlying siliciclastic materials. Such a succession allowed the formation of limestone clasts and of a slide sole constituted by water-saturated siliciclastic materials. In the southern part of the study area, the slide surface was located within the Murco Formation in the upper part of the collapse and just above the Murco Formation downslope. The collapse was frontally confined as it was blocked downslope by a topographic high that folded the whole limestone succession. In the northern part of the study area, the slide surface was also within the Murco Formation in the upper part, but occurs within the limestone succession downslope, due to higher subsidence that buried the sediments more deeply. The compressional structures affecting the limestone succession in the south are not observed there, suggesting that the toe of the collapse was not blocked here.
NASA Technical Reports Server (NTRS)
Nuth, J. A.; Brearley, A. J.; Scott, E. R. D.
2004-01-01
Comets, fine-grained matrices of chondrites, and chondritic interplanetary dust particles (IDPs) are each composed of both crystalline and amorphous silicates. The primitive solar nebula, in which comets and asteroids accreted, was formed from the collapsed core of a Giant Molecular Cloud, that, in turn, condensed from materials present in the interstellar medium (ISM). Despite observations that reveal the presence of crystalline magnesium silicate minerals in the shells of very high mass-loss-rate stars [1,2], typical silicate grains in the ISM are most likely to be amorphous, given their relatively long residence time in such a high radiation environment. An upper limit of 3% crystalline grains can be derived from their non-detection in spectra of ISM solids [3]. If the vast majority of grains that enter the primitive solar nebula are amorphous, then the observation of crystalline dust in comets and primitive chondrite matrices indicates the action of specific processes required to transform the amorphous starting materials into the crystals that are observed.
The effects of growth and collapse on the magmatic system below Mt Taranaki, New Zealand.
NASA Astrophysics Data System (ADS)
Procter, Jonathan; Marcroft, Grace; Zellmer, Georg; Zernack, Anke
2017-04-01
Mt. Taranaki exhibits one of the best long-term records of volcanic growth and destruction of any volcano worldwide, making it ideal for understanding the long-term effects of changing lithostatic pressure, or loading and unloading, on the magma chamber and magma supply. The ring-plain around Mt. Taranaki houses volcaniclastic deposits that provide a near continuous record of the evolution of the volcano, yet these records have remained relatively unexploited when investigating the interrelated cyclical phases of volcano collapse and growth, the geochemical evolution of the centre, and the consequent time-varying hazard potential. In this study, we systematically sampled pumice-rich tephra and pumice-rich mass flow deposits that were stratigraphically immediately before and after the 24,801 ± 268 years BP Pungarehu Formation debris avalanche ( 7.5 km3). Crystals (clinopyroxene and plagioclase) were characterised in detail. Mg and Fe zoning across selected crystals from samples pre-and post-debris avalanche were found to have completely equilibrated, yet zoning patterns in Al remained intact and showed major differences in their formation, allowing for the calculation of diffusion rates. These have enabled the determination of maximum residence times (depths and pressure regimes) of the magma system. It is intended that this technique will be applied across the stratigraphic record, which contains 14 collapse events. This will provide insights into crustal magma transport and residence times, and the propagation of fissures and the buoyancy of the magma pre- and post-collapse, in order to characterise the evolution of the centre and quantify the long-term relationship between magmatic rise and volcano growth and destruction.
NASA Astrophysics Data System (ADS)
Sruoga, P.; Ibañes, O. D.; Japas, M. S.; Urbina, N. E.
2017-05-01
Volcanism at Sierra del Morro represents the final stages of the flat-slab related magmatism in the easternmost San Luis Neogene Volcanic Belt. This 80 km-long NW-WNW-trending belt tracks the episodic inland migration of both magmatism and tectonic deformation since 18 Ma. The Sierra del Morro stands out in the Eastern Sierras Pampeanas as a metamorphic block uplifted during the Late Miocene-Pleistocene by a combination of magma injection and tectonic deformation. Although sequences that preserve stages of basement updoming are not often preserved, exposures in Sierra del Morro are exception in providing key evidence and insight into the involved processes. Based on the comprehensive study of volcanic stratigraphy and structures, the reconstruction of the volcanic architecture has been carried out. We infer a three stage evolution of the El Morro caldera as follows: 1) pre-collapse updoming and volcanism, 2) collapse caldera formation and 3) post-caldera volcanism. The ascent of magma is recorded in small tumescence sites, strongly controlled by oblique transtensional WNW-NW and ENE-striking brittle-ductile megashear zones. Even though the area affected by tumescence was large, magma injection progressed only locally. At Cerros Guanaco and Pampa, metamorphic rocks were updomed and strongly brecciated, whereas at Sierra del Morro magma was emplaced as pre-collapse domes with associated block-and-ash flows, ignimbrite caldera-forming eruptions and post-caldera lava domes and dykes. The caldera is located in the intersection of two major oblique transtensional WNW-NW and ENE-trending brittle-ductile megashear zones, where the highest positive dilatation occurred.
EMG based FES for post-stroke rehabilitation
NASA Astrophysics Data System (ADS)
Piyus, Ceethal K.; Anjaly Cherian, V.; Nageswaran, Sharmila
2017-11-01
Annually, 15 million in world population experiences stroke. Nearly 9 million stroke survivors every year experience mild to severe disability. The loss of upper extremity function in stroke survivors still remains a major rehabilitation challenge. The proposed EMG Abstract—Annually, 15 million in world population experiences stroke. Nearly 9 million stroke survivors every year experience mild to severe disability. The loss of upper extremity function in stroke survivors still remains a major rehabilitation challenge. The proposed EMG based FES system can be used for effective upper limb motor re-education in post stroke upper limb rehabilitation. The governing feature of the designed system is its synchronous activation, in which the FES stimulation is dependent on the amplitude of the EMG signal acquired from the unaffected upper limb muscle of the hemiplegic patient. This proportionate operation eliminates the undesirable damage to the patient’s skin by generating stimulus in proportion to voluntary EMG signals. This feature overcomes the disadvantages of currently available manual motor re-education systems. This model can be used in home-based post stroke rehabilitation, to effectively improve the upper limb functions.
Overview of the limnology of crater lake
Larson, G.L.
1996-01-01
Crater Lake occupies the collapsed caldera of volcanic Mount Mazama in Crater Lake National Park, Oregon. It is the deepest lake (589 m) in the United States and the 7th deepest lake in the world. The water column mixes to a depth of about 200 m in winter and spring from wind energy and cooling. The deep lake is mixed in winter and early spring each year when relatively cold water near the surface sinks and exchanges positions with water in the deep basins of the lake. The lake becomes thermally stratified in summer and early fall. The metalimnion extends to a depth of about 100 m; thus most of the water column is a cold hypolimnion. Secchi disk clarity measurements typically are in the upper-20-m range to the low-30-m range in summer and early fall. Concentrations of nutrients are low, although conductivity is relatively high owing to the inflow of hydrothermal fluids. Total chlorophyll is low in concentration, but typically maximal at a depth of 120 m during periods of thermal stratification. Primary production also is low, with the maximum levels occurring between the depth of 40 and 80 m. Phytoplankton taxa are spatially segregated from each other within the water column to a depth of 200 m in summer and early fall. The same generalization applies to the Zooplankton taxa. Water level, clarity, concentrations of total chlorophyll, primary production, and abundances of zooplankton and introduced kokanee salmon exhibit long-term fluctuations. Based primarily on a recent 10-year study of the lake, the lake is considered to be pristine, except for the consequences of fish introductions. ?? 1996 by the Northwest Scientific Association. All rights reserved.
Overview of the limnology of Crater Lake
Larson, Gary L.
1996-01-01
Crater Lake occupies the collapsed caldera of volcanic Mount Mazama in Crater Lake National Park, Oregon. It is the deepest lake (589 m) in the United States and the 7th deepest lake in the world. The water column mixes to a depth of about 200 m in winter and spring from wind energy and cooling. The deep lake is mixed in winter and early spring each year when relatively cold water near the surface sinks and exchanges positions with water in the deep basins of the lake. The lake becomes thermally stratified in summer and early fall. The metalimnion extends to a depth of about 100 m; thus most of the water column is a cold hypolimnion. Secchi disk clarity measurements typically are in the upper-20-m range to the low-30-m range in summer and early fall. Concentrations of nutrients are low, although conductivity is relatively high owing to the inflow of hydrothermal fluids. Total chlorophyll is low in concentration, but typically maximal at a depth of 120 m during periods of thermal stratification. Primary production also is low, with the maximum levels occurring between the depth of 40 and 80 m. Phytoplankton taxa are spatially segregated from each other within the water column to a depth of 200 m in summer and early fall. The same generalization applies to the zooplankton taxa. Water level, clarity, concentrations of total chlorophyll, primary production, and abundances of zooplankton and introduced kokanee salmon exhibit long-term fluctuations. Based primarily on a recent 10-year study of the lake, the lake is considered to be pristine, except for the consequences of fish introductions.
A sagging along the eastern Chianti Mts., Italy
NASA Astrophysics Data System (ADS)
Coltorti, M.; Ravani, S.; Cornamusini, G.; Ielpi, A.; Verrazzani, F.
2009-11-01
A deep-seated gravitational slope deformation (DGSD) affects the eastern side of the Chianti Mts. Ridge. It develops in an N-S to NW-SE direction and is > 10 km wide and 3-4 km long. This area corresponds to the eastern side of a main antiform, characterised by east-verging folds and thrusts involving bedrock of the Mesozoic-Paleogene Tuscan Units, particularly sandstones containing interlayered highly fractured and deformed Ligurian rocks (shales and limestones with olistostromes). The foot of the slope is characterised by tilted Plio-Pleistocene deposits unconformably sealing the bedrock structures as folds, thrusts and faults. The most significant morphological features are a main escarpment, trenches, several secondary and counter-slope escarpments that together indicate large-scale gravitational phenomena. The main escarpment is responsible for the headward retreat of the slope, and is deeply segmented by numerous arcuate niches that reveal differential movements of single blocks. The DGSD is also dissected by SW-NE trending streams that often deepen inside the N-S trenches. Minor landslides due to local instability are also present. At the foot of the slope, the older continental Pliocene deposits of the Upper Valdarno Basin crop out. Although tilted by tectonic movements, the deposits have not been severely affected by gravitational deformations. This indicates that the movement is a typical sagging, a large landslide at an embryonic stage, affecting the upper part of the slope but not reaching the valley bottom. The deformations are absorbed in the rock mass which is also partially drained by stream incision that prevents high pore pressure. The occurrence of down-slope and down-movement facing escarpments and up-slope and up-movement facing counter-slope escarpments indicate a sagging characterised by a listric spoon-shaped geometry. The DGSD has a style similar to crustal extensional tectonics such as Morton and Black's crustal attenuation model. Although few chronological indications of movements are present, the fact that Late Pleistocene debris deposits, widespread in the northern and central Apennines, are not found at the contact between the escarpment and the trenches suggests a post-glacial activity for at least part of the movements. Recognizing embryonic-stage collapse is of primary importance in assessing geological hazard and risk because rapid evolution and collapse could follow.
Weaver, Jonathan B; Kumar, Avinash B
2017-02-01
Case report. Operating room. 25YF, ASA IV E who underwent an emergent decompressive craniectomy for refractory intracranial hypertension secondary to acute intracranial hemorhage. A 25Y caucasian female presented with acute intracranial hemorrhage with intraventricular extension secondary to Moya Moya disease. Post admisison, she underwent an emergent decompressive craniectomy for medically refractory intracranial hypertension. Introperatively (post dural closure and bone flap removal) the patient developed acutely worsening peak and plateau pressures followed by pulseless electrical activity necessitating CPR with epinephrine and Vasopressin before return of circulation before return of circulation. Intraoperative TEE done during return of circulation, was essentially non diagnostic, the patient had normal breath sounds throughout, and non-contributory bronchoscopy findings. EKG, arterial blood pressure, heart rate, resp. rate, introperative tranesophageal echocardiogram (TEE), Pulse oximetry, serial arterial blood gases, introperative bronchoscopy, ventilatory peak pressures. A post operative chest CT revealed extensive pneumomediastinum with subcutaneous emphysema. The focussed introperative echocardiogram showed preserved left ventricular function and no evidence of tamponade physiology. Tension pneumomediastinum was the likely etiologic factor for the acute hemodynamic collapse and should be considered in the differential diagnosis of intraoperative circulatory arrest. Copyright © 2016 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Ye, F.; Zhao, L., Sr.; Chen, Z. Q.; Wang, X.
2017-12-01
Calcium and carbon cycles are tightly related in the ocean, for example, through continental weathering and deposition of carbonate, thus, very important for exploring evolutions of marine environment during the earth history. The end-Permian mass extinction is the biggest biological disaster in the Phanerozoic and there are several studies talking about variations of calcium isotopes across the Permian-Triassic boundary (PTB). However, these studies are all from the Tethys regions (Payne et al., 2010; Hinojosa et al., 2012), while the Panthalassic Ocean is still unknown to people. Moreover, evolutions of the calcium isotopes during the Early to Late Triassic is also poorly studied (Blattler et al., 2012). Here, we studied an Uppermost Permian to Upper Triassic shallow water successions (Kamura section, Southwest Japan) in the Central Panthalassic Ocean. The Kamura section is far away from the continent without any clastic pollution, therefore, could preserved reliable δ44/40Cacarb signals. Conodont zonation and carbonate carbon isotope also provide precious time framework which is necessary for the explaining of the δ44/40Cacarb profile. In Kamura, δ44/40Cacarb and δ13Ccarb both exhibit negative excursions across the PTB, the δ44/40Cacarb value in the end-Permian is 1.0398‰ then abrupt decrease to the minimum value of 0.1524‰. CO2-driven global ocean acidification best explains the coincidence of the δ44/40Cacarb excursion with negative excursions in the δ13Ccarb of carbonates until the Early Smithian(N1a, N1b, N1c, P1, N2, P2). In the Middle and the Late Triassic, the δ44/40 Cacarb average approximately 1.1‰. During the Middle and Late Triassic, strong relationships between δ44/40Cacarb and δ13Ccarb are collapsed, indicating a normal pH values of the seawater in those time. The Siberian Trap volcanism probably played a significant role on the δ44/40Cacarb until the late Early Triassic. After that, δ44/40Cacarb was mostly controlled by carbonate flux.
NASA Astrophysics Data System (ADS)
Finn, Carol A.; Deszcz-Pan, Maryla; Ball, Jessica L.; Bloss, Benjamin J.; Minsley, Burke J.
2018-05-01
Water-saturated hydrothermal alteration reduces the strength of volcanic edifices, increasing the potential for catastrophic sector collapses that can lead to far traveled and destructive debris flows. Intense hydrothermal alteration significantly lowers the resistivity and magnetization of volcanic rock and therefore hydrothermally altered rocks can be identified with helicopter electromagnetic and magnetic measurements. Geophysical models constrained by rock properties and geologic mapping show that intensely altered rock is restricted to two small (500 m diameter), >150 m thick regions around Sherman Crater and Dorr Fumarole Field at Mount Baker, Washington. This distribution of alteration contrasts with much thicker and widespread alteration encompassing the summits of Mounts Adams and Rainier prior to the 5600 year old Osceola collapse, which is most likely due to extreme erosion and the limited duration of summit magmatism at Mount Baker. In addition, the models suggest that the upper 300 m of rock contains water which could help to lubricate potential debris flows. Slope stability modeling incorporating the geophysically modeled distribution of alteration and water indicates that the most likely and largest ( 0.1 km3) collapses are from the east side of Sherman Crater. Alteration at Dorr Fumarole Field raises the collapse hazard there, but not significantly because of its lower slope angles. Geochemistry and analogs from other volcanoes suggest a model for the edifice hydrothermal system.
Pomajzl, Ryan Joseph; Baker, Erin Ann; Baker, Kevin Charles; Fleischer, Mackenzie Marie; Salisbury, Meagan R; Phillips, Dylan M; Fortin, Paul Thomas
2016-09-01
Fresh osteochondral allografting of the talus is one treatment option for large chondral defects. Following positive early term results, failure rates of up to 35% have been reported. A retrieval study was performed to characterize failed talar allografts. Failed fresh osteochondral allografts of the talus were retrieved on revision. Cases of deep infection were excluded. After tissue fixation, samples were decalcified, embedded, and stained with Safranin-O/Fast Green, osteocalcin, tumor necrosis factor alpha (TNF-α), CD4, CD8, and CD68. Slides were graded according to the modified Mankin scoring system or severity scale. Medical record review was performed. Eight allografts (7 patients) were retrieved from patients, following an average term of implantation of 31 months (range, 12-58). There were 3 types of allografts in this series (hemidome, n=5; segmental, n=2; bipolar, n=1). Reasons for transplantation were post-traumatic arthritis or osteonecrosis; reasons for revision were graft failure/collapse, nonunion, progressive arthritis, and/or pain. Prior to revision, all grafts exhibited collapse and subchondral lucencies. At the graft host interface, Safranin-O staining demonstrated substantial loss of sulfated glycosaminoglycans, Osteocalcin immunostaning was nearly absent, CD68 (indicating osteoclast activity) was predominantly exhibited, and CD4+ helper T cells as well as CD8+ cytotoxic T cells and NK cells-cell types commonly implicated in allogeneic organ transplant rejection-were found in high concentrations. TNF-α was present throughout the graft. A histopathologic analysis of 8 retrieved, failed talar allografts was performed. Graft failure appeared to be primarily biologic, with an extensive loss of viable cartilaginous and osseous tissue at the graft-host interface. This study provides the first evidence of a potential CD4+ and CD8+ lymphocyte-mediated failure mechanism in fresh osteochondral allografts that were revised following collapse. Level IV, case series. © The Author(s) 2016.
Costa Rica's Chain of laterally collapsed volcanoes.
NASA Astrophysics Data System (ADS)
Duarte, E.; Fernandez, E.
2007-05-01
From the NW extreme to the SW end of Costa Rica's volcanic backbone, a number of laterally collapsed volcanoes can be observed. Due to several factors, attention has been given to active volcanoes disregarding the importance of collapsed features in terms of assessing volcanic hazards for future generations around inhabited volcanoes. In several cases the typical horseshoe shape amphitheater-like depression can be easily observed. In other cases due to erosion, vegetation, topography, seismic activity or drastic weather such characteristics are not easily recognized. In the order mentioned above appear: Orosi-Cacao, Miravalles, Platanar, Congo, Von Frantzius, Cacho Negro and Turrialba volcanoes. Due to limited studies on these structures it is unknown if sector collapse occurred in one or several phases. Furthermore, in the few studied cases no evidence has been found to relate collapses to actual eruptive episodes. Detailed studies on the deposits and materials composing dome-like shapes will shed light on unsolved questions about petrological and chemical composition. Volume, form and distance traveled by deposits are part of the questions surrounding most of these collapsed volcanoes. Although most of these mentioned structures are extinct, at least Irazú volcano (active volcano) has faced partial lateral collapses recently. It did presented strombolian activity in the early 60s. Collapse scars show on the NW flank show important mass removal in historic and prehistoric times. Moreover, in 1994 a minor hydrothermal explosion provoked the weakening of a deeply altered wall that holds a crater lake (150m diameter, 2.6x106 ). A poster will depict images of the collapsed volcanoes named above with mayor descriptive characteristics. It will also focus on the importance of deeper studies to assess the collapse potential of Irazú volcano with related consequences. Finally, this initiative will invite researchers interested in such topic to join future studies in these Costarrican volcanoes.
Precombination Cloud Collapse and Baryonic Dark Matter
NASA Technical Reports Server (NTRS)
Hogan, Craig J.
1993-01-01
A simple spherical model of dense baryon clouds in the hot big bang 'strongly nonlinear primordial isocurvature baryon fluctuations' is reviewed and used to describe the dependence of cloud behavior on the model parameters, baryon mass, and initial over-density. Gravitational collapse of clouds before and during recombination is considered including radiation diffusion and trapping, remnant type and mass, and effects on linear large-scale fluctuation modes. Sufficiently dense clouds collapse early into black holes with a minimum mass of approx. 1 solar mass, which behave dynamically like collisionless cold dark matter. Clouds below a critical over-density, however, delay collapse until recombination, remaining until then dynamically coupled to the radiation like ordinary diffuse baryons, and possibly producing remnants of other kinds and lower mass. The mean density in either type of baryonic remnant is unconstrained by observed element abundances. However, mixed or unmixed spatial variations in abundance may survive in the diffuse baryon and produce observable departures from standard predictions.
Savel'ev, Sergey E; Zagoskin, Alexandre M
2018-06-25
A popular interpretation of the "collapse" of the wave function is as being the result of a local interaction ("measurement") of the quantum system with a macroscopic system ("detector"), with the ensuing loss of phase coherence between macroscopically distinct components of its quantum state vector. Nevetheless as early as in 1953 Renninger suggested a Gedankenexperiment, in which the collapse is triggered by non-observation of one of two mutually exclusive outcomes of the measurement, i.e., in the absence of interaction of the quantum system with the detector. This provided a powerful argument in favour of "physical reality" of (nonlocal) quantum state vector. In this paper we consider a possible version of Renninger's experiment using the light propagation through a birefringent quantum metamaterial. Its realization would provide a clear visualization of a wave function collapse produced by a "non-measurement", and make the concept of a physically real quantum state vector more acceptable.
Cooperation, cheating, and collapse in microbial populations
NASA Astrophysics Data System (ADS)
Gore, Jeff
2012-02-01
Natural populations can suffer catastrophic collapse in response to small changes in environmental conditions, and recovery after such a collapse can be exceedingly difficult. We have used laboratory yeast populations to study proposed early warning signals of impending extinction. Yeast cooperatively breakdown the sugar sucrose, meaning that there is a minimum number of cells required to sustain the population. We have demonstrated experimentally that the fluctuations in the population size increase in magnitude and become slower as the population approaches collapse. The cooperative nature of yeast growth on sucrose suggests that the population may be susceptible to cheater cells, which do not contribute to the public good and instead merely take advantage of the cooperative cells. We have confirmed this possibility experimentally by using a cheater yeast strain that lacks the gene encoding the cooperative behavior [1]. However, recent results in the lab demonstrate that the presence of a bacterial competitor may drive cooperation within the yeast population.[4pt] [1] Gore et al, Nature 459, 253 -- 256 (2009)
Endoscopy of the upper respiratory tract during treadmill exercise: a clinical study of 100 horses.
Kannegieter, N J; Dore, M L
1995-03-01
Endoscopy of the upper respiratory tract was performed in 100 horses during high speed treadmill exercise. Reasons for endoscopy were a history of an abnormal noise during exercise in 75 horses, poor performance in 17 horses and to evaluate the results of upper respiratory tract surgery in 8 horses. Of the 75 horses with a history of an abnormal noise during exercise the cause was determined in 67 (89%). Endoscopic abnormalities were detected at rest in 40 of these 75 horses (53%). In these 40 horses, a similar diagnosis as to the cause of the abnormal noise was made at rest and during exercise on the treadmill in 19 cases, while in the remaining 21 the endoscopic findings during exercise varied from that seen at rest. This included 3 horses in which a diagnosis was made at rest but no abnormalities were detected during exercise. Some of the findings during treadmill endoscopy included laryngeal dysfunction, grades 3, 4 and 5 (22 cases), dorsal displacement of the soft palate (20), epiglottic entrapment (8), epiglottic flutter (4), aryepiglottic fold flutter (4), pharyngeal collapse (3), arytenoiditis (3), vocal cord flutter (3), false nostril noise (2), pharyngeal lymphoid hyperplasia (2), soft palate haemorrhage (1) and positional arytenoid collapse (1). More than one abnormality was observed during exercise in 7 horses. A complete and correct diagnosis based on the resting endoscopy findings alone was made in 19 (25%) of these 75 cases. In the 17 horses examined because of poor performance, no abnormalities were detected during treadmill endoscopy that were not evident at rest.(ABSTRACT TRUNCATED AT 250 WORDS)
Cortical Drive to Breathe during Wakefulness in Patients with Obstructive Sleep Apnea Syndrome.
Launois, Claire; Attali, Valérie; Georges, Marjolaine; Raux, Mathieu; Morawiec, Elise; Rivals, Isabelle; Arnulf, Isabelle; Similowski, Thomas
2015-11-01
The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity. The objective of this study was to test whether awake OSAS patients would exhibit a similar cortical activity. Descriptive physiology study. Sleep laboratory in a large university affiliated tertiary hospital. 26 patients with moderate OSAS according to polysomnography (5 < apnea-hypopnea index [AHI] ≤ 30, n = 14) or severe OSAS (AHI > 30, n = 12); 13 non-OSAS patients for comparison. None. Respiratory time-locked electroencephalographic segments ensemble averaged and analyzed for slow premotor potentials preceding inspiration ("pre-inspiratory potentials" [PIPs]). PIPs were present in 1/13 controls and 11/26 patients (P = 0.0336; 4/14 "moderate" and 7/12 "severe" patients). Awake OSAS patients therefore exhibit respiratory-related cortical activity during quiet breathing significantly more frequently than non-OSAS individuals. The corresponding PIPs resemble those observed during prepared voluntary inspirations and in response to experimental inspiratory loads in normal subjects, which involve a cortical network comprising the supplementary motor area. A respiratory-related cortical activity could contribute to the increased neural drive to upper airway and to inspiratory muscles that has previously been described in obstructive sleep apnea, and could therefore contribute to the arousal-dependent compensation of upper airway abnormalities. Whether or not such cortical compensatory mechanisms have cognitive consequences remains to be determined. © 2015 Associated Professional Sleep Societies, LLC.
Constitutive model for porous materials
DOE Office of Scientific and Technical Information (OSTI.GOV)
Weston, A.M.; Lee, E.L.
1982-01-01
A simple pressure versus porosity compaction model is developed to calculate the response of granular porous bed materials to shock impact. The model provides a scheme for calculating compaction behavior when relatively limited material data are available. While the model was developed to study porous explosives and propellants, it has been applied to a much wider range of materials. The early development of porous material models, such as that of Hermann, required empirical dynamic compaction data. Erkman and Edwards successfully applied the early theory to unreacted porous high explosives using a Gruneisen equation of state without yield behavior and withoutmore » trapped gas in the pores. Butcher included viscoelastic rate dependance in pore collapse. The theoretical treatment of Carroll and Holt is centered on the collapse of a circular pore and includes radial inertia terms and a complex set of stress, strain and strain rate constitutive parameters. Unfortunately data required for these parameters are generally not available. The model described here is also centered on the collapse of a circular pore, but utilizes a simpler elastic-plastic static equilibrium pore collapse mechanism without strain rate dependence, or radial inertia terms. It does include trapped gas inside the pore, a solid material flow stress that creates both a yield point and a variation in solid material pressure with radius. The solid is described by a Mie-Gruneisen type EOS. Comparisons show that this model will accurately estimate major mechanical features which have been observed in compaction experiments.« less
Black hole formation in a contracting universe
DOE Office of Scientific and Technical Information (OSTI.GOV)
Quintin, Jerome; Brandenberger, Robert H., E-mail: jquintin@physics.mcgill.ca, E-mail: rhb@hep.physics.mcgill.ca
We study the evolution of cosmological perturbations in a contracting universe. We aim to determine under which conditions density perturbations grow to form large inhomogeneities and collapse into black holes. Our method consists in solving the cosmological perturbation equations in complete generality for a hydrodynamical fluid. We then describe the evolution of the fluctuations over the different length scales of interest and as a function of the equation of state for the fluid, and we explore two different types of initial conditions: quantum vacuum and thermal fluctuations. We also derive a general requirement for black hole collapse on sub-Hubble scales,more » and we use the Press-Schechter formalism to describe the black hole formation probability. For a fluid with a small sound speed (e.g., dust), we find that both quantum and thermal initial fluctuations grow in a contracting universe, and the largest inhomogeneities that first collapse into black holes are of Hubble size and the collapse occurs well before reaching the Planck scale. For a radiation-dominated fluid, we find that no black hole can form before reaching the Planck scale. In the context of matter bounce cosmology, it thus appears that only models in which a radiation-dominated era begins early in the cosmological evolution are robust against the formation of black holes. Yet, the formation of black holes might be an interesting feature for other models. We comment on a number of possible alternative early universe scenarios that could take advantage of this feature.« less
NASA Astrophysics Data System (ADS)
Stratford, W. R.; Knight, T. P.; Peirce, C.; Watts, A. B.; Grevemeyer, I.; Paulatto, M.; Bassett, D.; Hunter, J.; Kalnins, L. M.
2012-12-01
Variations in trench and forearc morphology, and lithospheric velocity structure are observed where the Louisville Ridge seamount chain subducts at the Tonga-Kermadec Trench. Subduction of these seamounts has affected arc and back-arc processes along the trench for the last 5 Myr. High subduction rates (80 mm/yr in the north, 55 mm/yr in the south), a fast southwards migrating collision zone (~180 km/myr), and the obliquity of the subducting plate and the seamount chain to the trench, make this an ideal location to study the effects of seamount subduction on lithospheric structure. The "before and after" subduction regions have been targeted by several large-scale geophysical projects in recent years; the most recent being the R/V Sonne cruise SO215 in 2011. The crust and upper mantle velocity structure observed in profiles along strike of the seamount chain and perpendicular to the trench from this study, are compared to a similar profile from SO195, recorded ~100 km to the north. The affects of the passage of the seamounts through the subduction system are indicated by velocity anomalies in the crust and mantle of the overriding plate. Preliminary results indicate that in the present collision zone, mantle velocities (Pn) are reduced by ~5%. Around 100 km to the north, where seamounts are inferred to have subducted ~1 Myr ago, a reduction of 7% in mantle P-wave velocity is observed. The width of the trench slope and elevation of the forearc also vary along strike. At the collision zone a >100 km wide collapse region of kilometre-scale block faults comprise the trench slope, while the forearc is elevated. The elevated forearc has a 5 km think upper crust with a Vp of 2.5-5.5 km/s and the collapse zone also has upper crustal velocities as low as 2.5 km/s. To the east in the Pacific Plate, lower P-wave velocities are also observed and attributed to serpentinization due to deep fracturing in the outer trench high. Large bending faults permeate the crust and the Osbourn Seamount, currently on the verge of subduction, is fractured stepwise down into the trench. Pn velocities in the hinge zone of the Pacific Plate are as low as 7.3 km/s indicating that fracturing and serpentinization may also extend to sub-crustal depths. Finally, trench-parallel variations in subduction zone velocity structure are used to infer the degree to which seamount subduction has altered the physical state of the Pacific and Indo-Australian plates both pre- and post subduction.
Raske, Matthew; Weisse, Chick; Berent, Allyson C; McDougall, Renee; Lamb, Kenneth
2018-03-01
Intraluminal tracheal stenting is a minimally invasive procedure shown to have variable degrees of success in managing clinical signs associated with tracheal collapse syndrome (CTCS) in dogs. Identify immediate post-stent changes in tracheal diameter, determine the extent of stent migration, and stent shortening after stent placement in the immediate-, short-, and long-term periods, and evaluate inter-observer reliability of radiographic measurements. Fifty client-owned dogs. Retrospective study in which medical records were reviewed in dogs with CTCS treated with an intraluminal tracheal stent. Data collected included signalment, location, and type of collapse, stent diameter and length, and post-stent placement radiographic follow-up times. Radiographs were used to obtain pre-stent tracheal measurements and post-stent placement measurements. Immediate mean percentage change was 5.14%, 5.49%, and 21.64% for cervical, thoracic inlet, and intra-thoracic tracheal diameters, respectively. Ultimate mean follow-up time was 446 days, with mean percentage change of 2.55%, 15.09%, and 8.65% for cervical, thoracic inlet, and intra-thoracic tracheal diameters, respectively. Initial mean stent length was 26.72% higher than nominal length and ultimate long-term tracheal mean stent shortening was only 9.90%. No significant stent migration was identified in the immediate, short-, or long-term periods. Good inter-observer agreement of radiographic measurements was found among observers of variable experience level. Use of an intraluminal tracheal stent for CTCS is associated with minimal stent shortening with no clinically relevant stent migration after fluoroscopic placement. Precise stent sizing and placement techniques likely play important roles in avoiding these reported complications. Copyright © 2018 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.
Al-Mutairi, Fouad H; Fallows, Stephen J; Abukhudair, Waleed A; Islam, Baharul B; Morris, Michael M
2012-11-01
To assess the effect of early use of continuous positive airway pressure (CPAP) therapy to treat or prevent acute atelectasis in post-operative cardiac patients particularly smokers and elderly patients. A pilot study suggested enrolling at least 32 participants in each group to be significant. One hundred and eight patients from King Fahd Armed Forces Hospital, Jeddah, Kingdom of Saudi Arabia who met the inclusion criteria participated in this study conducted between March 2010 and March 2011. The participants were divided randomly into 3 groups, incentive spirometry (IS) therapy, and CPAP therapy every 2 (CPAP 2 hrs), or 4 hours (CPAP 4 hrs). Inspiratory capacity (IC) was used to compare the 3 therapy regimes. Simultaneously, respiratory rate (RR), heart rate (HR) and oxygen saturation (SpO2) were measured for all groups. Failure was defined as requiring intubation, bi-level positive airway pressure, or added chest physiotherapy. Thirty-six patients participated in each group (98 male and 10 female, with a mean age of 62+/-9.3 years). The IC increased significantly in the CPAP 2 hrs group when compared with the control group or the CPAP 4hrs group. The SpO2 decreased significantly in the control group and the CPAP 4 hrs groups when compared with the CPAP 2 hrs group. Also, there were no significant differences in RR and HR between all groups. Early use of CPAP via mask therapy for half an hour every 2 hours had better outcomes to re-open collapsed alveoli after cardiac surgery.
NASA Astrophysics Data System (ADS)
Ott, Christian D.; Roberts, Luke F.; da Silva Schneider, André; Fedrow, Joseph M.; Haas, Roland; Schnetter, Erik
2018-03-01
We present a first study of the progenitor star dependence of the three-dimensional (3D) neutrino mechanism of core-collapse supernovae. We employ full 3D general-relativistic multi-group neutrino radiation-hydrodynamics and simulate the postbounce evolutions of progenitors with zero-age main sequence masses of 12, 15, 20, 27, and 40 M ⊙. All progenitors, with the exception of the 12 M ⊙ star, experience shock runaway by the end of their simulations. In most cases, a strongly asymmetric explosion will result. We find three qualitatively distinct evolutions that suggest a complex dependence of explosion dynamics on progenitor density structure, neutrino heating, and 3D flow. (1) Progenitors with massive cores, shallow density profiles, and high post-core-bounce accretion rates experience very strong neutrino heating and neutrino-driven turbulent convection, leading to early shock runaway. Accretion continues at a high rate, likely leading to black hole formation. (2) Intermediate progenitors experience neutrino-driven, turbulence-aided explosions triggered by the arrival of density discontinuities at the shock. These occur typically at the silicon/silicon–oxygen shell boundary. (3) Progenitors with small cores and density profiles without strong discontinuities experience shock recession and develop the 3D standing-accretion shock instability (SASI). Shock runaway ensues late, once declining accretion rate, SASI, and neutrino-driven convection create favorable conditions. These differences in explosion times and dynamics result in a non-monotonic relationship between progenitor and compact remnant mass.
Steffen, Armin; Sommer, J Ulrich; Hofauer, Benedikt; Maurer, Joachim T; Hasselbacher, Katrin; Heiser, Clemens
2018-02-01
Upper airway stimulation (UAS) of the hypoglossal nerve has been implemented in the routine clinical practice for patients with moderate-to-severe obstructive sleep apnea (OSA) who could not adhere to continuous positive airway pressure. This study reports objective and patient-reported outcome after 12 months of implantation. Multicenter prospective single-arm study. Consecutive patients who received the UAS system (Inspire Medical Systems, Inc., Minneapolis, Minnesota, Maple Grove, MN, U.S.A.) were enrolled in three German centers. Key study exclusion criteria included body mass index > 35 kg/m 2 , apnea-hypopnea index (AHI) < 15 or > 65, or complete concentric collapse at the soft palate during sedated endoscopy. Data collection at 6- and 12-month visit include home sleep test and patient-reported outcome measures. Among the total of 60 participants, the median AHI reduced from 28.6 to 9.5 from baseline to 12 months. Patient-reported outcome measured in Epworth Sleepiness Scale and Functional Outcomes of Sleep Questionnaire both improved significantly from baseline to 12 months. The average usage time was 39.1 ± 14.9 hours per week among all participants based on recordings by the implanted device. One patient requested a removal of the device for cosmetic and other personal reasons and was completed without sequelae. This study supported that UAS is a safe and effective treatment option for patients with OSA in routine clinical practice. 4. Laryngoscope, 128:509-515, 2018. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.
Hauser, Robert A; Abler, Victor; Eyal, Eli; Eliaz, Rom E
2016-10-01
To evaluate the efficacy of rasagiline versus placebo in a pooled population of patients with early Parkinson's disease (PD). TEMPO and ADAGIO were Phase III studies that evaluated the symptomatic efficacy of rasagiline versus placebo in patients with early PD. This meta-analysis included Unified Parkinson's Disease Rating Scale (UPDRS) observations from weeks 12, 24 and 36 in ADAGIO and from weeks 14 and 26 in TEMPO; TEMPO visits were recoded to weeks 12 and 24, respectively. The present analysis includes all patients who received rasagiline 1 mg/day, 2 mg/day or placebo, and had ≥1 post-baseline observations and a subgroup of patients whose baseline UPDRS Total scores were ≥27 (Upper Quartile population). Change from baseline in UPDRS scores were evaluated using mixed models repeated measures analyses. Of the 1578 patients randomized to the two studies, 1546 patients met criteria for inclusion in the meta-analysis. Effects on UPDRS Total, motor and activities of daily living scores were significantly better for both doses of rasagiline compared with placebo at all time periods. The Upper Quartile population included 402 patients with a UPDRS Total score ≥27 at baseline. These patients generally demonstrated a larger magnitude of treatment effect than was seen in the full population. This meta-analysis confirms the efficacy of rasagiline monotherapy over 36 weeks. Although TEMPO and ADAGIO are considered studies of "very early" PD, both contained a sizeable pool of patients with more severe disease. In addition, the meta-analysis showed a larger magnitude of effect in patients with more severe baseline disease.
Buyukavci, Raikan; Akturk, Semra; Ersoy, Yüksel
2018-02-07
Ultrasound-guided botulinum toxin type A injection is an effective treatment for spasticity. Euro-musculus spasticity approach is a new method for administering injections to the correct point of the correct muscle. The clinical outcomes of this practical approach is not yet available in the literature. The purpose of this study was to evaluate the effects on spasticity and the functional outcomes of ultrasound guided botulinum toxin type A injections via the Euro-musculus spasticity approach to treat upper limb spasticity in post-stroke patients. An observational study. Inpatient post-stroke patients. Twenty five post-stroke patients with post-stroke upper limb spasticity were recruited. The ultrasound-guided botulinum toxin type A injections were administered into the spastic target muscles using the Euro-musculus spasticity approach, and all of the patients were enrolled in rehabilitation programmes after the injections. This research included the innervation zone and injection site figures and ultrasound images of each muscle in the upper limb. The degree of spasticity was assessed via the Modified Ashworth Scale and the upper limb motor function via the Fugl Meyer Upper Extremity Scale at the baseline and 4 and 12 weeks after the botulinum toxin type A injection. Significant decreases in the Modified Ashworth Scale scores of the upper limb flexor muscle tone measured 4 and 12 weeks after the botulinum toxin type A injection were found when compared to the baseline scores (p<0.025). When compared with the baseline Fugl Meyer Upper Extremity subgroup scores, the sitting position, wrist and total scores at 4 and 12 weeks were significantly improved (p<0.025). However, only the Fugl Meyer Upper Extremity hand scores were significantly improved 12 weeks after the injection (p<0.025). Ultrasound-guided botulinum toxin type A injection via the Euro- musculus spasticity approach is a practical and effective method for administering injections to the correct point of the correct muscle. Ultrasound-guided botulinum toxin type A injections combined with rehabilitation programmes decrease spasticity and improve the upper extremity motor functions in stroke patients. This new approach for ultrasound- guided botulinum toxin type A injection is very practical and effective method for upper extremity spasticity.
External rhinoplasty: a critical analysis of 500 cases.
Foda, Hossam M T
2003-06-01
The study presents a comprehensive statistical analysis of a series of 500 consecutive rhinoplasties of which 380 (76 per cent) were primary and 120 (24 per cent) were secondary cases. All cases were operated upon using the external rhinoplasty technique; simultaneous septal surgery was performed in 350 (70 per cent) of the cases. Deformities of the upper two-thirds of the nose that occurred significantly more in the secondary cases included; dorsal saddling, dorsal irregularities, valve collapse, open roof and pollybeak deformities. In the lower third of the nose; secondary cases showed significantly higher incidences of depressed tip, tip over-rotation, tip asymmetry, retracted columella, and alar notching. Suturing techniques were used significantly more in primary cases, while in secondary cases grafting techniques were used significantly more. The complications encountered intra-operatively included; septal flap tears (2.8 per cent) and alar cartilage injury (1.8 per cent), while post-operative complications included; nasal trauma (one per cent), epistaxis (two per cent), infection (2.4 per cent), prolonged oedema (17 per cent), and nasal obstruction (0.8 per cent). The overall patient satisfaction rate was 95.6 per cent and the transcolumellar scar was found to be unacceptable in only 0.8 per cent of the patients.
Wang, Yue; Yu, Lei; Fu, Jianming; Fang, Qiang
2014-04-01
In order to realize an individualized and specialized rehabilitation assessment of remoteness and intelligence, we set up a remote intelligent assessment system of upper limb movement function of post-stroke patients during rehabilitation. By using the remote rehabilitation training sensors and client data sampling software, we collected and uploaded the gesture data from a patient's forearm and upper arm during rehabilitation training to database of the server. Then a remote intelligent assessment system, which had been developed based on the extreme learning machine (ELM) algorithm and Brunnstrom stage assessment standard, was used to evaluate the gesture data. To evaluate the reliability of the proposed method, a group of 23 stroke patients, whose upper limb movement functions were in different recovery stages, and 4 healthy people, whose upper limb movement functions were normal, were recruited to finish the same training task. The results showed that, compared to that of the experienced rehabilitation expert who used the Brunnstrom stage standard table, the accuracy of the proposed remote Brunnstrom intelligent assessment system can reach a higher level, as 92.1%. The practical effects of surgery have proved that the proposed system could realize the intelligent assessment of upper limb movement function of post-stroke patients remotely, and it could also make the rehabilitation of the post-stroke patients at home or in a community care center possible.
Contrasting catastrophic eruptions predicted by different intrusion and collapse scenarios.
Rincón, M; Márquez, A; Herrera, R; Alonso-Torres, A; Granja-Bruña, J L; van Wyk de Vries, B
2018-04-18
Catastrophic volcanic eruptions triggered by landslide collapses can jet upwards or blast sideways. Magma intrusion is related to both landslide-triggered eruptive scenarios (lateral or vertical), but it is not clear how such different responses are produced, nor if any precursor can be used for forecasting them. We approach this problem with physical analogue modelling enhanced with X-ray Multiple Detector Computed Tomography scanning, used to track evolution of internal intrusion, and its related faulting and surface deformation. We find that intrusions produce three different volcano deformation patterns, one of them involving asymmetric intrusion and deformation, with the early development of a listric slump fault producing pronounced slippage of one sector. This previously undescribed early deep potential slip surface provides a unified explanation for the two different eruptive scenarios (lateral vs. vertical). Lateral blast only occurs in flank collapse when the intrusion has risen into the sliding block. Otherwise, vertical rather than lateral expansion of magma is promoted by summit dilatation and flank buttressing. The distinctive surface deformation evolution detected opens the possibility to forecast the possible eruptive scenarios: laterally directed blast should only be expected when surface deformation begins to develop oblique to the first major fault.
NASA Astrophysics Data System (ADS)
Praeg, D.; Silva, C. G.; dos Reis, A. T.; Ketzer, J. M.; Unnithan, V.; Perovano Da Silva, R. J.; Cruz, A. M.; Gorini, C.
2017-12-01
The stability of natural gas hydrate accumulations on continental margins has mainly been considered in terms of changes in seawater pressures and temperatures driven from above by climate. We present evidence from the Amazon deep-sea fan for stability zone changes driven from below by fluid upwelling. A grid of 2D and 3D multichannel seismic data show the upper Amazon fan in water depths of 1200-2000 m to contain a discontinuous bottom-simulating seismic reflection (BSR) that forms `patches' 10-50 km wide and up to 140 km long, over a total area of at least 5000 km2. The elongate BSR patches coincide with anticlinal thrust-folds that record on-going gravitational collapse of the fan above décollements at depths of up to 10 km. The BSR lies within 100-300 m of seafloor, in places rising beneath features that seafloor imagery show to be pockmarks and mud volcanoes, some venting gas to the water column. The BSR patches are up to 500 m shallower than predicted for methane hydrate based on geothermal gradients as low as 17˚C/km measured within the upper fan, and inversion of the BSR to obtain temperatures at the phase boundary indicates gradients 2-5 times background levels. We interpret the strongly elevated BSR patches to record upwelling of warm gas-rich fluids through thrust-fault zones 101 km wide. We infer this process to favour gas hydrate occurrences that are concentrated in proportion to flux and locally pierced by vents, and that will be sensitive to temporal variations in the upward flux of heat and gas. Thus episodes of increased flux, e.g. during thrusting, could dissociate gas hydrates to trigger slope failures and/or enhanced gas venting to the ocean. Structurally-driven fluid flow episodes could account for evidence of recurrent large-scale failures from the compressive belt on the upper fan during its Neogene collapse, and provide a long-term alternative to sea level triggering. The proposed mechanism of upward flux links the distribution and stability of gas hydrate occurrences (and gas vents) to the internal dynamics of deep-sea depocentres, in all water depths that structural pathways for fluid migration may form. Gravitational collapse is increasingly recognized to affect passive continental margins, and our findings challenge global models of hydrate inventory over time based solely on in situ methanogenesis.
NASA Astrophysics Data System (ADS)
Mulas, M.; Bowman, L.; Roverato, M.; Larrea Marquez, P.; Casado, I.
2017-12-01
Debris avalanche deposits (DAD) are common products of catastrophic volcanic edifice collapses. These failure events leave peculiar horseshoe-shaped scars on the summits of stratovolcanoes. Cubilche Volcano (3826 masl), located S of the city of Ibarra (Imbabura Province) and E of the dormant Imbabura volcano, displays a distinct horseshoe-shaped scar towards the N. This post-collapse edifice that we name "Old Cubilche Volcano" (OCV) hosts an additional edifice, "Young Cubilche Volcano" (YCV), which partially covers the southern flank of OCV. Knowledge of Cubilche is critical because of its close proximity to the provincial capital of Ibarra. In fact, Imbabura edifice was built over the northwestern slope of OCV and partially covered it. The studied DAD (unknown age) has been recently linked to Imbabura Volcano as a product of its northwestern sector collapse (LePennec et al., 2011). Alternatively, previous work proposed that the DAD, covering 80 km2 and reaching >13 km distance with an estimated volume of 1.6 km3, was the product of the older OCV (Ruiz, 2003). To constrain the source of the DAD, detailed fieldwork with granulometric, petrological, and geochemical analyses of the deposit was conducted. Preliminary data points to Cubilche as the most likely source for this DAD in accordance with Ruiz (2003). The shaded relief image of the present day OCV shows that the morphology of the volcano is well-preserved on its southern, eastern, and western flanks. This allows the reconstruction of the morphology of OCV prior to the collapse through interpolation of elevation and altitude data of the preserved flanks. A DEM of the present day topography (12m horizontal resolution) obtained from TanDEM-X data was used for extrapolating the morphology. This methodology shows that the post-collapse base of the amphitheater was reconstructed by removing the relief of the present day YCV. The reconstructed topography of OCV shows that it could have been a symmetric cone, reaching a maximum elevation of 4300 masl with a missing volume of 1.2-1.5 km3. Based on this scenario, the deposit originating from OCV's main collapse should have a volume >1.2 km3 in accordance with the volume calculated for DAD.
Multidisciplinary management of Paget-Schroetter syndrome. A case series of eight patients.
Rosa Salazar, Vladimir; Otálora Valderrama, Sonia Del Pilar; Hernández Contreras, María Encarnación; García Pérez, Bartolomé; Arroyo Tristán, Andrés Del Amor; García Méndez, María Del Mar
2015-08-01
Paget-Schroetter syndrome (PSS) in the context of upper extremity deep venous thrombosis (DVT) is an uncommon but potentially very serious condition affecting young, healthy adults, in which secondary post-thrombotic syndrome (PTS) can be a complication with major implications. The best treatment option remains controversial, with current guidelines recommending anticoagulation for at least 3 months. However, an incidence of PTS of approximately 50% after 6 months, 30% after 1 year and 25% after 2 years has been found using this therapeutic approach. Consequently, specialized units recommend local thrombolysis and early decompressive surgery. We describe a series of eight cases treated in this way. None of the patients showed signs of complications, and an early return to regular activities with no PTS was observed in 90% of cases. Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved.
White, David P; Younes, Magdy K
2012-10-01
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive collapse of the pharyngeal airway during sleep. Control of pharyngeal patency is a complex process relating primarily to basic anatomy and the activity of many pharyngeal dilator muscles. The control of these muscles is regulated by a number of processes including respiratory drive, negative pressure reflexes, and state (sleep) effects. In general, patients with OSA have an anatomically small airway the patency of which is maintained during wakefulness by reflex-driven augmented dilator muscle activation. At sleep onset, muscle activity falls, thereby compromising the upper airway. However, recent data suggest that the mechanism of OSA differs substantially among patients, with variable contributions from several physiologic characteristics including, among others: level of upper airway dilator muscle activation required to open the airway, increase in chemical drive required to recruit the pharyngeal muscles, chemical control loop gain, and arousal threshold. Thus, the cause of sleep apnea likely varies substantially between patients. Other physiologic mechanisms likely contributing to OSA pathogenesis include falling lung volume during sleep, shifts in blood volume from peripheral tissues to the neck, and airway edema. Apnea severity may progress over time, likely due to weight gain, muscle/nerve injury, aging effects on airway anatomy/collapsibility, and changes in ventilatory control stability. © 2012 American Physiological Society
NASA Astrophysics Data System (ADS)
Reisswig, C.; Ott, C. D.; Abdikamalov, E.; Haas, R.; Mösta, P.; Schnetter, E.
2013-10-01
We study the collapse of rapidly rotating supermassive stars that may have formed in the early Universe. By self-consistently simulating the dynamics from the onset of collapse using three-dimensional general-relativistic hydrodynamics with fully dynamical spacetime evolution, we show that seed perturbations in the progenitor can lead to the formation of a system of two high-spin supermassive black holes, which inspiral and merge under the emission of powerful gravitational radiation that could be observed at redshifts z≳10 with the DECIGO or Big Bang Observer gravitational-wave observatories, assuming supermassive stars in the mass range 104-106M⊙. The remnant is rapidly spinning with dimensionless spin a*=0.9. The surrounding accretion disk contains ˜10% of the initial mass.
Cassini observations of Io's visible aurorae
Geissler, P.; McEwen, A.; Porco, C.; Strobel, D.; Saur, J.; Ajello, J.; West, R.
2004-01-01
More than 500 images of Io in eclipse were acquired by the Cassini spacecraft in late 2000 and early 2001 as it passed through the jovian system en route to Saturn (Porco et al., 2003, Science 299, 1541-1547). Io's bright equatorial glows were detected in Cassini's near-ultraviolet filters, supporting the interpretation that the visible emissions are predominantly due to molecular SO2. Detailed comparisons of laboratory SO2 spectra with the Cassini observations indicate that a mixture of gases contribute to the equatorial emissions. Potassium is suggested by new detections of the equatorial glows at near-infrared wavelengths from 730 to 800 nm. Neutral atomic oxygen and sodium are required to explain the brightness of the glows at visible wavelengths. The molecule S2 is postulated to emit most of the glow intensity in the wavelength interval from 390 to 500 nm. The locations of the visible emissions vary in response to the changing orientation of the external magnetic field, tracking the tangent points of the jovian magnetic field lines. Limb glows distinct from the equatorial emissions were observed at visible to near-infrared wavelengths from 500 to 850 nm, indicating that atomic O, Na, and K are distributed across Io's surface. Stratification of the atmosphere is demonstrated by differences in the altitudes of emissions at various wavelengths: SO2 emissions are confined to a region close to Io's surface, whereas neutral oxygen emissions are seen at altitudes that reach up to 900 km, or half the radius of the satellite. Pre-egress brightening demonstrates that light scattered into Jupiter's shadow by gases or aerosols in the giant planet's upper atmosphere contaminates images of Io taken within 13 minutes of entry into or emergence from Jupiter's umbra. Although partial atmospheric collapse is suggested by the longer timescale for post-ingress dimming than pre-egress brightening, Io's atmosphere must be substantially supported by volcanism to retain auroral emissions throughout the duration of eclipse. ?? 2004 Elsevier Inc. All rights reserved.
Pyloric sphincter characteristics using EndoFLIP® in gastroparesis.
Saadi, M; Yu, D; Malik, Z; Parkman, H P; Schey, R
2018-04-27
Pyloric sphincter abnormalities may be detected in gastroparesis. Botulinum toxin A (BoNT/A) injection into the pylorus has been used to treat gastroparesis with varying results. The aim of the present article was to assess whether pyloric sphincter characteristics using the endoscopic functional lumen imaging probe (EndoFLIP ® ) with impedance planimetry in patients with gastroparesis correlated with symptoms, gastric emptying, and therapeutic response to pyloric sphincter BoNT/A injection. EndoFLIP ® study was performed on patients undergoing gastroparesis treatment with BoNT/A. The gastroparesis cardinal symptom index (GCSI) was applied prior to treatment and at post-treatment weeks 2, 4, 8, and 12. Forty-four patients were enrolled (30 with idiopathic gastroparesis, 14 with diabetic gastroparesis). Smaller pyloric diameter, cross-sectional area (CSA), and distensibility correlated with worse vomiting and retching severity at baseline. Greater gastric retention tended to correlate with decreased CSA and pyloric distensibility. BoNT/A treatment resulted in a significant decrease in the GCSI score at 2 and 4 weeks after treatment, but not at post-treatment weeks 8 or 12. Nausea, early satiety, postprandial fullness, and upper abdominal pain improved up to 12 weeks, whereas loss of appetite, stomach fullness, and stomach visibly larger improved only up to 4 weeks. Retching and vomiting failed to improve. Greater pyloric compliance at baseline correlated with greater improvement in early satiety and náusea at 8 weeks and greater pyloric distensibility correlated with improvement in upper abdominal pain. EndoFLIP ® characteristics of the pylorus provided important pathophysiologic information in patients with gastroparesis, in relation to symptoms, gastric emptying, and predicting the response to treatment directed at the pylorus. Copyright © 2018 Asociación Mexicana de Gastroenterología. Publicado por Masson Doyma México S.A. All rights reserved.
Adult obstructive sleep apnoea.
Jordan, Amy S; McSharry, David G; Malhotra, Atul
2014-02-22
Obstructive sleep apnoea is an increasingly common disorder of repeated upper airway collapse during sleep, leading to oxygen desaturation and disrupted sleep. Features include snoring, witnessed apnoeas, and sleepiness. Pathogenesis varies; predisposing factors include small upper airway lumen, unstable respiratory control, low arousal threshold, small lung volume, and dysfunctional upper airway dilator muscles. Risk factors include obesity, male sex, age, menopause, fluid retention, adenotonsillar hypertrophy, and smoking. Obstructive sleep apnoea causes sleepiness, road traffic accidents, and probably systemic hypertension. It has also been linked to myocardial infarction, congestive heart failure, stroke, and diabetes mellitus though not definitively. Continuous positive airway pressure is the treatment of choice, with adherence of 60-70%. Bi-level positive airway pressure or adaptive servo-ventilation can be used for patients who are intolerant to continuous positive airway pressure. Other treatments include dental devices, surgery, and weight loss. Copyright © 2014 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Gázquez, F.; Evans, N. P.; Bauska, T. K.; Hodell, D. A.
2016-12-01
Paleoclimate evidence suggests that drought coincided with the collapse of the lowland Classic Maya civilization between 800 and 1000 AD. However, attempts to quantitatively determine the magnitude of hydrologic change have met with mixed results. Several periods of gypsum deposition have been documented in Lake Chichancanab (Yucatan Peninsula, Mexico) sediment cores and interpreted as representing times of drought. Here we analyzed the triple oxygen (17O/16O, 18O/16O) and hydrogen (2H/1H) isotope ratios of the gypsum hydration water to obtain the δ18O, δD, 17O-excess, and d-excess of the lake water during the drought periods. By comparing these results to measurements made on the modern lake, rain and ground waters, we are able to better constrain the hydrological changes that occurred in the lake basin during the Terminal Classic Drought (TCD). During the TCD, the δ18O and δD of the lake water increased compared with modern values, whereas the 17O-excess, and d-excess decreased. The isotopic composition of lake water (δ17O, δ18O and δD, and derived d-excess and 17O-excess) is sensitive to changes in atmospheric relative humidity and temperature. We modeled the isotopic data and found the observed changes can be explained by a 10% reduction in relative humidity compared to modern conditions. This reduction in relative humidity was accompanied by a significant increase in evaporation over precipitation. Furthermore, we show that the driest period occurred during the early phase of the TCD (ca 770-870 AD) when the Classic Maya declined. Previous studies based on stalagmite δ18O records suggested that the greatest drought period occurred in the Postclassic Period (1020 and 1100 AD) and post-dated the collapse. Our findings from Lake Chichancanab suggest that the changes to the hydrological budget during the TCD were greater than those during the early Postclassic Period.
Rogers, E. M.
1990-01-01
Past investigations by myself and others on the role of the mass media in disasters indicate that news people typically find themselves in situations of uncertainty, ambiguity, and conflicting information; the communication and transportation services that these people use in covering a story become inoperative. However, the media are expected to make sense of the disaster situation almost immediately. the difficulties of doing so were reflected by the ABC Goodyear Blimp footage of the collapsed Nimitz Freeway in Oakland, California, broadcast nationally on the evening of October 17, 1989. The televised picture showed the disastrous results of the Loma Prieta earthquake, but for an hour or more the announcer could not correctly identify what was being shown. He did not seem to realize that the upper deck of the freeway had collapsed on the lower deck, crushing vechiles and people.
Thermodynamic models for bounding pressurant mass requirements of cryogenic tanks
NASA Technical Reports Server (NTRS)
Vandresar, Neil T.; Haberbusch, Mark S.
1994-01-01
Thermodynamic models have been formulated to predict lower and upper bounds for the mass of pressurant gas required to pressurize a cryogenic tank and then expel liquid from the tank. Limiting conditions are based on either thermal equilibrium or zero energy exchange between the pressurant gas and initial tank contents. The models are independent of gravity level and allow specification of autogenous or non-condensible pressurants. Partial liquid fill levels may be specified for initial and final conditions. Model predictions are shown to successfully bound results from limited normal-gravity tests with condensable and non-condensable pressurant gases. Representative maximum collapse factor maps are presented for liquid hydrogen to show the effects of initial and final fill level on the range of pressurant gas requirements. Maximum collapse factors occur for partial expulsions with large final liquid fill fractions.
The development of upper limb movements: from fetal to post-natal life.
Zoia, Stefania; Blason, Laura; D'Ottavio, Giuseppina; Biancotto, Marina; Bulgheroni, Maria; Castiello, Umberto
2013-01-01
The aim of this longitudinal study was to investigate how the kinematic organization of upper limb movements changes from fetal to post-natal life. By means of off-line kinematical techniques we compared the kinematics of hand-to-mouth and hand-to-eye movements, in the same individuals, during prenatal life and early postnatal life, as well as the kinematics of hand-to-mouth and reaching-toward-object movements in the later age periods. Movements recorded at the 14(th), 18(th) and 22(nd) week of gestation were compared with similar movements recorded in an ecological context at 1, 2, 3, 4, 8, and 12 months after birth. The results indicate a similar kinematic organization depending on movement type (i.e., eye, mouth) for the infants at one month and for the fetuses at 22 weeks of gestation. At two and three months such differential motor planning depending on target is lost and no statistical differences emerge. Hand to eye movements were no longer observed after the fourth month of life, therefore we compared kinematics for hand to mouth with hand to object movements. Results of these analyses revealed differences in the performance of hand to mouth and reaching to object movements in the length of the deceleration phase of the movement, depending on target. Data are discussed in terms of how the passage from intrauterine to extra-uterine environments modifies motor planning. These results provide novel evidence of how different types of upper extremity movements, those directed towards one's own face and those directed to external objects, develop.
Radio Constraints on Long-lived Magnetar Remnants in Short Gamma-Ray Bursts
NASA Astrophysics Data System (ADS)
Fong, W.; Metzger, B. D.; Berger, E.; Özel, F.
2016-11-01
The merger of a neutron star (NS) binary may result in the formation of a rapidly spinning magnetar. The magnetar can potentially survive for seconds or longer as a supramassive NS before collapsing to a black hole if, indeed, it collapses at all. During this process, a fraction of the magnetar’s rotational energy of ˜1053 erg is transferred via magnetic spin-down to the surrounding ejecta. The resulting interaction between the ejecta and the surrounding circumburst medium powers a year-long or greater synchrotron radio transient. We present a search for radio emission with the Very Large Array following nine short-duration gamma-ray bursts (GRBs) at rest-frame times of ≈1.3-7.6 yr after the bursts, focusing on those events that exhibit early-time excess X-ray emission that may signify the presence of magnetars. We place upper limits of ≲18-32 μJy on the 6.0 GHz radio emission, corresponding to spectral luminosities of ≲(0.05-8.3) × 1039 erg s-1. Comparing these limits to the predicted radio emission from a long-lived remnant and incorporating measurements of the circumburst densities from broadband modeling of short GRB afterglows, we rule out a stable magnetar with an energy of 1053 erg for half of the events in our sample. A supramassive remnant that injects a lower rotational energy of 1052 erg is ruled out for a single event, GRB 050724A. This study represents the deepest and most extensive search for long-term radio emission following short GRBs to date, and thus the most stringent limits placed on the physical properties of magnetars associated with short GRBs from radio observations.
Genetics Home Reference: Sjögren-Larsson syndrome
... view the expand/collapse boxes. Description Sjögren-Larsson syndrome is a condition characterized by dry, scaly skin (ichthyosis); neurological problems; and eye problems. These symptoms are apparent by early childhood ...
Black hole formation in the early Universe
NASA Astrophysics Data System (ADS)
Latif, M. A.; Schleicher, D. R. G.; Schmidt, W.; Niemeyer, J.
2013-08-01
Supermassive black holes with up to a 109 M⊙ dwell in the centres of present-day galaxies, and their presence has been confirmed at z ≥ 6. Their formation at such early epochs is still an enigma. Different pathways have been suggested to assemble supermassive black holes in the first billion years after the big bang. Direct collapse has emerged as a highly plausible scenario to form black holes as it provides seed masses of 105-106 M⊙. Gravitational collapse in atomic cooling haloes with virial temperatures Tvir ≥ 104 K may lead to the formation of massive seed black holes in the presence of an intense background ultraviolet flux. Turbulence plays a central role in regulating accretion and transporting angular momentum. We present here the highest resolution cosmological large eddy simulations to date which track the evolution of high-density regions on scales of 0.25 au beyond the formation of the first peak, and study the impact of subgrid-scale turbulence. The peak density reached in these simulations is 1.2 × 10-8 g cm-3. Our findings show that while fragmentation occasionally occurs, it does not prevent the growth of a central massive object resulting from turbulent accretion and occasional mergers. The central object reaches ˜1000 M⊙ within four free-fall times, and we expect further growth up to 106 M⊙ through accretion in about 1 Myr. The direct collapse model thus provides a viable pathway of forming high-mass black holes at early cosmic times.
Bellet, R Nicole; Lamb, Rhonda L; Gould, Tonya D; Bartlett, Harold J
2017-01-01
Chronic neuro-musculoskeletal pain is an important complication of open-heart surgery (OHS). To better understand the development and natural course of neuro-musculoskeletal pain in the immediate post-OHS period, this prospective longitudinal study assessed the prevalence and degree of pain and shoulder disability, and areas of pain pre- and post-OHS. Usual medical, nursing, and physiotherapy care was provided including early extubation, education, walking, sitting out of bed, and upper, lower limb, and trunk exercises from day 1 post-operation. Of 114 elective patients who provided consent, 98 subjects were surveyed preoperatively, and at week 6 and week 12 post-OHS. Open and closed questions encompassed numerical rating of pain scales for various body areas summed as a total pain score (TPS), the shoulder disability score (SDS), exercise compliance, and sternal clicking. Usual care comprised mobility exercises, walking program, and cardiac rehabilitation referral. Survey return rates were 100%, 88%, and 82%, respectively. Of the 76 (78%) subjects with complete data sets, 68% subjects reported a history of previous neuro-musculoskeletal injuries/conditions preoperatively while prevalence for neuro-musculoskeletal pain was 64%, 88%, and 67% and 38%, 63%, and 42% for shoulder disability, at the three assessments. In all, 11% subjects reported sternal clicking at week 6 and 7% at week 12. Pain commonly occurred in the lower back and neck preoperatively, and in front of the chest, neck, rib cage, upper back, and left shoulder at week 6. Rib cage pain alone remained significantly greater than preoperative levels by week 12 post-OHS. Preoperative SDS was positively correlated with post-OHS length of stay; women had higher SDSs than men at week 6 and week 12 and week 12 SDS was negatively correlated with height. Surgical risk score was negatively correlated with change in SDS and TPS from pre-operation to week 12. In conclusion, neuro-musculoskeletal pain and shoulder disability were common preoperatively and while prevalence increased at week 6 post-OHS, overall preoperative levels were restored by week 12.
Bellet, R Nicole; Lamb, Rhonda L; Gould, Tonya D; Bartlett, Harold J
2017-01-01
Chronic neuro-musculoskeletal pain is an important complication of open-heart surgery (OHS). To better understand the development and natural course of neuro-musculoskeletal pain in the immediate post-OHS period, this prospective longitudinal study assessed the prevalence and degree of pain and shoulder disability, and areas of pain pre- and post-OHS. Usual medical, nursing, and physiotherapy care was provided including early extubation, education, walking, sitting out of bed, and upper, lower limb, and trunk exercises from day 1 post-operation. Of 114 elective patients who provided consent, 98 subjects were surveyed preoperatively, and at week 6 and week 12 post-OHS. Open and closed questions encompassed numerical rating of pain scales for various body areas summed as a total pain score (TPS), the shoulder disability score (SDS), exercise compliance, and sternal clicking. Usual care comprised mobility exercises, walking program, and cardiac rehabilitation referral. Survey return rates were 100%, 88%, and 82%, respectively. Of the 76 (78%) subjects with complete data sets, 68% subjects reported a history of previous neuro-musculoskeletal injuries/conditions preoperatively while prevalence for neuro-musculoskeletal pain was 64%, 88%, and 67% and 38%, 63%, and 42% for shoulder disability, at the three assessments. In all, 11% subjects reported sternal clicking at week 6 and 7% at week 12. Pain commonly occurred in the lower back and neck preoperatively, and in front of the chest, neck, rib cage, upper back, and left shoulder at week 6. Rib cage pain alone remained significantly greater than preoperative levels by week 12 post-OHS. Preoperative SDS was positively correlated with post-OHS length of stay; women had higher SDSs than men at week 6 and week 12 and week 12 SDS was negatively correlated with height. Surgical risk score was negatively correlated with change in SDS and TPS from pre-operation to week 12. In conclusion, neuro-musculoskeletal pain and shoulder disability were common preoperatively and while prevalence increased at week 6 post-OHS, overall preoperative levels were restored by week 12. PMID:29066939
Clark, Allan K.; Golab, James A.; Morris, Robert R.
2016-11-28
During 2014–16, the U.S. Geological Survey, in cooperation with the Edwards Aquifer Authority, documented the geologic framework and hydrostratigraphy of the Edwards and Trinity aquifers within northern Bexar and Comal Counties, Texas. The Edwards and Trinity aquifers are major sources of water for agriculture, industry, and urban and rural communities in south-central Texas. Both the Edwards and Trinity are classified as major aquifers by the State of Texas.The purpose of this report is to present the geologic framework and hydrostratigraphy of the Edwards and Trinity aquifers within northern Bexar and Comal Counties, Tex. The report includes a detailed 1:24,000-scale hydrostratigraphic map, names, and descriptions of the geology and hydrostratigraphic units (HSUs) in the study area.The scope of the report is focused on geologic framework and hydrostratigraphy of the outcrops and hydrostratigraphy of the Edwards and Trinity aquifers within northern Bexar and Comal Counties, Tex. In addition, parts of the adjacent upper confining unit to the Edwards aquifer are included.The study area, approximately 866 square miles, is within the outcrops of the Edwards and Trinity aquifers and overlying confining units (Washita, Eagle Ford, Austin, and Taylor Groups) in northern Bexar and Comal Counties, Tex. The rocks within the study area are sedimentary and range in age from Early to Late Cretaceous. The Miocene-age Balcones fault zone is the primary structural feature within the study area. The fault zone is an extensional system of faults that generally trends southwest to northeast in south-central Texas. The faults have normal throw, are en echelon, and are mostly downthrown to the southeast.The Early Cretaceous Edwards Group rocks were deposited in an open marine to supratidal flats environment during two marine transgressions. The Edwards Group is composed of the Kainer and Person Formations. Following tectonic uplift, subaerial exposure, and erosion near the end of Early Cretaceous time, the area of present-day south-central Texas was again submerged during the Late Cretaceous by a marine transgression resulting in deposition of the Georgetown Formation of the Washita Group.The Early Cretaceous Edwards Group, which overlies the Trinity Group, is composed of mudstone to boundstone, dolomitic limestone, argillaceous limestone, evaporite, shale, and chert. The Kainer Formation is subdivided into (bottom to top) the basal nodular, dolomitic, Kirschberg Evaporite, and grainstone members. The Person Formation is subdivided into (bottom to top) the regional dense, leached and collapsed (undivided), and cyclic and marine (undivided) members.Hydrostratigraphically the rocks exposed in the study area represent a section of the upper confining unit to the Edwards aquifer, the Edwards aquifer, the upper zone of the Trinity aquifer, and the middle zone of the Trinity aquifer. The Pecan Gap Formation (Taylor Group), Austin Group, Eagle Ford Group, Buda Limestone, and Del Rio Clay are generally considered to be the upper confining unit to the Edwards aquifer.The Edwards aquifer was subdivided into HSUs I to VIII. The Georgetown Formation of the Washita Group contains HSU I. The Person Formation of the Edwards Group contains HSUs II (cyclic and marine members [Kpcm], undivided), III (leached and collapsed members [Kplc,] undivided), and IV (regional dense member [Kprd]), and the Kainer Formation of the Edwards Group contains HSUs V (grainstone member [Kkg]), VI (Kirschberg Evaporite Member [Kkke]), VII (dolomitic member [Kkd]), and VIII (basal nodular member [Kkbn]).The Trinity aquifer is separated into upper, middle, and lower aquifer units (hereinafter referred to as “zones”). The upper zone of the Trinity aquifer is in the upper member of the Glen Rose Limestone. The middle zone of the Trinity aquifer is formed in the lower member of the Glen Rose Limestone, Hensell Sand, and Cow Creek Limestone. The regionally extensive Hammett Shale forms a confining unit between the middle and lower zones of the Trinity aquifer. The lower zone of the Trinity aquifer consists of the Sligo and Hosston Formations, which do not crop out in the study area.The upper zone of the Trinity aquifer is subdivided into five informal HSUs (top to bottom): cavernous, Camp Bullis, upper evaporite, fossiliferous, and lower evaporite. The middle zone of the Trinity aquifer is composed of the (top to bottom) Bulverde, Little Blanco, Twin Sisters, Doeppenschmidt, Rust, Honey Creek, Hensell, and Cow Creek HSUs. The underlying Hammett HSU is a regional confining unit between the middle and lower zones of the Trinity aquifer. The lower zone of the Trinity aquifer is not exposed in the study area.Groundwater recharge and flow paths in the study area are influenced not only by the hydrostratigraphic characteristics of the individual HSUs but also by faults and fractures and geologic structure. Faulting associated with the Balcones fault zone (1) might affect groundwater flow paths by forming a barrier to flow that results in water moving parallel to the fault plane, (2) might affect groundwater flow paths by increasing flow across the fault because of fracturing and juxtaposing porous and permeable units, or (3) might have no effect on the groundwater flow paths.The hydrologic connection between the Edwards and Trinity aquifers and the various HSUs is complex. The complexity of the aquifer system is a combination of the original depositional history, bioturbation, primary and secondary porosity, diagenesis, and fracturing of the area from faulting. All of these factors have resulted in development of modified porosity, permeability, and transmissivity within and between the aquifers. Faulting produced highly fractured areas that have allowed for rapid infiltration of water and subsequently formed solutionally enhanced fractures, bedding planes, channels, and caves that are highly permeable and transmissive. The juxtaposition resulting from faulting has resulted in areas of interconnectedness between the Edwards and Trinity aquifers and the various HSUs that form the aquifers.
Landlordism, Rent Regulation and the Labour Party in mid-twentieth century Britain, 1950-64.
Child, Phil
2018-03-01
This article examines the politics of private renting in 1950s and early 1960s Britain, through the radical approach taken by Labour Party towards private landlords. Through setting the radical aims of Labour in a mid-twentieth-century context of decrepit housing, rising rents and sluggish public housing programmes, Labour's rationale in arguing for the 'abolition' of the private landlord is more transparent. This article takes a chronological approach, investigating what actions Labour actors took, at local and national level, and what effect this had on the wider housing market. Part one takes a long view of Labour attitudes to the private rented sector. Part two explores the policy of 'municipalization'-the attempt to place rented homes under local authority control. Part three discusses the post-1962 policy shift to state-sponsored 'improvement' of private rented housing, prior to Labour's victory at the 1964 general election. Three key arguments are made: that Labour's radicalism hastened the collapse of the post-war private rented sector; that rental market weaknesses indicated the confused place of renting in the 'tenurial pattern'; and that the proposed 'abolition' of private landlords had a direct effect on slum clearance and the composition of British cities. The conclusion suggests that Labour's pursuit of the private landlord can shed light on the vast urban transformations of the post-war period. It invites greater attention to be paid to the effects that political ideas had on the composition of the twentieth-century British housing market.
NASA Astrophysics Data System (ADS)
Everett, M. E.; Udphuay, S.; Warden, R.
2007-05-01
The 1944 D-Day invasion site at Pointe du Hoc, Normandy, France is an important WWII battlefield and cultural resource but is at risk from chalk cliff collapse. The American Battle Monuments Commission tasked us to evaluate the geohazard to the observation post and other cliff-side buildings of historical significance. Geophysical multi-electrode resistivity profiling is used to study cliff stability and the condition of the observation- post foundations. Preliminary 2-D geological interpretations are provided of individual profiles. The copious steel, concrete and void spaces at the site renders hydrogeological interpretation challenging but tractable. The cliff face appears to be relatively intact and well-drained. Several routes taken by groundwater into fractures within the chalk were identified mainly on the western side of the site. The eastern side is drier and somewhat sheltered from the Atlantic storms but may contain large void spaces that could efficiently transmit groundwater flow during heavy precipitation events, thereby imperiling the major antiaircraft gun emplacement occupied by Col. Rudder in the early days of the Allied invasion. The forward German observation post perched close to the sea stack, which now hosts the U.S. Ranger memorial, may be moving with the soil and not securely anchored to bedrock. A complex failure mechanism is identified as a combination of groundwater dissolution of the fractured chalk and sea wave attack at the cliff base.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Diot, Quentin, E-mail: quentin.diot@ucdenver.edu; Kavanagh, Brian; Vinogradskiy, Yevgeniy
2015-11-15
Purpose: To differentiate radiation-induced fibrosis from regional lung collapse outside of the high dose region in patients treated with stereotactic body radiation therapy (SBRT) for lung tumors. Methods: Lung deformation maps were computed from pre-treatment and post-treatment computed tomography (CT) scans using a point-to-point translation method. Fifty anatomical landmarks inside the lung (vessel or airway branches) were matched on planning and follow-up scans for the computation process. Two methods using the deformation maps were developed to differentiate regional lung collapse from fibrosis: vector field and Jacobian methods. A total of 40 planning and follow-ups CT scans were analyzed for 20more » lung SBRT patients. Results: Regional lung collapse was detected in 15 patients (75%) using the vector field method, in ten patients (50%) using the Jacobian method, and in 12 patients (60%) by radiologists. In terms of sensitivity and specificity the Jacobian method performed better. Only weak correlations were observed between the dose to the proximal airways and the occurrence of regional lung collapse. Conclusions: The authors presented and evaluated two novel methods using anatomical lung deformations to investigate lung collapse and fibrosis caused by SBRT treatment. Differentiation of these distinct physiological mechanisms beyond what is usually labeled “fibrosis” is necessary for accurate modeling of lung SBRT-induced injuries. With the help of better models, it becomes possible to expand the therapeutic benefits of SBRT to a larger population of lung patients with large or centrally located tumors that were previously considered ineligible.« less
Xenon isotopic composition of the Mid Ocean Ridge Basalt (MORB) source
NASA Astrophysics Data System (ADS)
Peto, M. K.; Mukhopadhyay, S.
2012-12-01
Although convection models do not preclude preservation of smaller mantle regions with more pristine composition throughout Earth's history, it has been widely assumed that the moon forming giant impact likely homogenizes the whole mantle following a magma ocean that extended all the way to the bottom of the mantle. Recent findings of tungsten and xenon heterogeneities in the mantle [1,2,3,4], however, imply that i) the moon forming giant impact may not have homogenized the whole mantle and ii) plate tectonics was inefficient in erasing early formed compositional differences, particularly for the xenon isotopes. Therefore, the xenon isotope composition in the present day mantle still preserves a memory of early Earth processes. However, determination of the xenon isotopic composition of the mantle source is still scarce, since the mantle composition is overprinted by post-eruptive atmospheric contamination in basalts erupted at ocean islands and mid ocean ridges. The xenon composition of the depleted upper mantle has been defined by the gas rich sample, 2πD43 (also known as "popping rock"), from the North Atlantic (13° 469`N). However, the composition of a single sample is not likely to define the composition of the upper mantle, especially since popping rock has an "enriched" trace element composition. We will present Ne, Ar and Xe isotope data on MORB glass samples with "normal" helium isotope composition (8±1 Ra) from the Southeast Indian Ridge, the South Atlantic Ridge, the Sojourn Ridge, the Juan de Fuca, the East Pacific Rise, and the Gakkel Ridge. Following the approach of [1], we correct for syn- and post-eruptive atmosphere contamination, and determine the variation of Ar and Xe isotope composition of the "normal" MORB source. We investigate the effect of atmospheric recycling in the variation of MORB mantle 40Ar/36Ar and 129Xe/130Xe ratios, and attempt to constrain the average upper mantle argon and xenon isotopic compositions. [1] Mukhopadhyay, Nature 2012; [2] Tucker et al., EPSL (in review); [3] Moreira et al., Nature 1998 [4] Touboul et al., Science 2012.
Vanbellingen, Tim; Filius, Suzanne J; Nyffeler, Thomas; van Wegen, Erwin E H
2017-01-01
Approximately 70-80% of stroke survivors have limited activities of daily living, mainly due to dexterous problems. Videogame-based training (VBT) along with virtual reality seems to be beneficial to train upper limb function. To evaluate the usability of VBT using the Leap Motion Controller (LMC) to train fine manual dexterity in the early rehabilitation phase of stroke patients as an add-on to conventional therapy. Additionally, this study aimed to estimate the feasibility and potential efficacy of the VBT. During 3 months, 64 stroke patients were screened for eligibility, 13 stroke patients were included (4 women and 9 men; age range: 24-91 years; mean time post stroke: 28.2 days). Nine sessions of 30 min VBT, three times per week as an add-on to conventional therapy with stroke inpatients. Primary outcome was the usability of the system measured with the System Usability Scale. Secondary outcomes concerning feasibility were the compliance rate calculated from the total time spent on the intervention (TT) compared to planned time, the opinion of participants via open-end questions, and the level of active participation measured with the Pittsburgh Rehabilitation Participation Scale. Regarding the potential efficacy secondary outcomes were: functional dexterity measured with the Nine Hole Peg Test (NHPT), subjective dexterity measured with the Dexterity Questionnaire 24, grip strength measured with the Jamar dynamometer, and motor impairment of the upper limb measured with the Fugl-Meyer Upper Extremity (FM-UE) scale. Primarily, the usability of the system was good to excellent. The patient's perception of usability remained stable over a mean period of 3 weeks of VBT. Secondly, the compliance rate was good, and the level of active participation varied between good and very good. The opinion of the participants revealed that despite individual differences, the overall impression of the therapy and device was good. Patients showed significant improvements in hand dexterity. No changes were found in motor impairment of the upper limb (FM-UE) during intervention. VBT using LMC is a usable rehabilitation tool to train dexterity in the early rehabilitation phase of stroke inpatients.
Constraints on high-energy neutrino emission from SN 2008D
NASA Astrophysics Data System (ADS)
IceCube Collaboration; Abbasi, R.; Abdou, Y.; Abu-Zayyad, T.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Andeen, K.; Auffenberg, J.; Bai, X.; Baker, M.; Barwick, S. W.; Bay, R.; Bazo Alba, J. L.; Beattie, K.; Beatty, J. J.; Bechet, S.; Becker, J. K.; Becker, K.-H.; Benabderrahmane, M. L.; Ben Zvi, S.; Berdermann, J.; Berghaus, P.; Berley, D.; Bernardini, E.; Bertrand, D.; Besson, D. Z.; Bissok, M.; Blaufuss, E.; Blumenthal, J.; Boersma, D. J.; Bohm, C.; Bose, D.; Böser, S.; Botner, O.; Braun, J.; Buitink, S.; Carson, M.; Chirkin, D.; Christy, B.; Clem, J.; Clevermann, F.; Cohen, S.; Colnard, C.; Cowen, D. F.; D'Agostino, M. V.; Danninger, M.; Davis, J. C.; De Clercq, C.; Demirörs, L.; Depaepe, O.; Descamps, F.; Desiati, P.; de Vries-Uiterweerd, G.; DeYoung, T.; Díaz-Vélez, J. C.; Dierckxsens, M.; Dreyer, J.; Dumm, J. P.; Duvoort, M. R.; Ehrlich, R.; Eisch, J.; Ellsworth, R. W.; Engdegård, O.; Euler, S.; Evenson, P. A.; Fadiran, O.; Fazely, A. R.; Fedynitch, A.; Feusels, T.; Filimonov, K.; Finley, C.; Foerster, M. M.; Fox, B. D.; Franckowiak, A.; Franke, R.; Gaisser, T. K.; Gallagher, J.; Geisler, M.; Gerhardt, L.; Gladstone, L.; Glüsenkamp, T.; Goldschmidt, A.; Goodman, J. A.; Grant, D.; Griesel, T.; Gro, A.; Grullon, S.; Gurtner, M.; Ha, C.; Hallgren, A.; Halzen, F.; Han, K.; Hanson, K.; Helbing, K.; Herquet, P.; Hickford, S.; Hill, G. C.; Hoffman, K. D.; Homeier, A.; Hoshina, K.; Hubert, D.; Huelsnitz, W.; Hül, J. P.; Hulth, P. O.; Hultqvist, K.; Hussain, S.; Ishihara, A.; Jacobsen, J.; Japaridze, G. S.; Johansson, H.; Joseph, J. M.; Kampert, K. H.; Kappes A.; Karg, T.; Karle, A.; Kelley, J. L.; Kemming, N.; Kenny, P.; Kiryluk, J.; Kislat, F.; Klein, S. R.; Köhne, J. H.; Kohnen, G.; Kolanoski, H.; Köpke, L.; Koskinen, D. J.; Kowalski, M.; Kowarik, T.; Krasberg, M.; Krings, T.; Kroll, G.; Kuehn, K.; Kuwabara, T.; Labare, M.; Lafebre, S.; Laihem, K.; Landsman, H.; Larson, M. J.; Lauer, R.; Lehmann, R.; Lünemann, J.; Madsen, J.; Majumdar, P.; Marotta, A.; Maruyama, R.; Mase, K.; Matis, H. S.; Matusik, M.; Meagher, K.; Merck, M.; Mészáros, P.; Meures, T.; Middell, E.; Milke, N.; Miller, J.; Montaruli, T.; Morse, R.; Movit, S. M.; Nahnhauer, R.; Nam, J. W.; Naumann, U.; Nießen, P.; Nygren, D. R.; Odrowski, S.; Olivas, A.; Olivo, M.; O'Murchadha, A.; Ono, M.; Panknin, S.; Paul, L.; Pérez de los Heros, C.; Petrovic, J.; Piegsa, A.; Pieloth, D.; Porrata, R.; Posselt, J.; Price, P. B.; Prikockis, M.; Przybylski, G. T.; Rawlins, K.; Redl, P.; Resconi, E.; Rhode, W.; Ribordy, M.; Rizzo, A.; Rodrigues, J. P.; Roth, P.; Rothmaier, F.; Rott, C.; Ruhe, T.; Rutledge, D.; Ruzybayev, B.; Ryckbosch, D.; Sander, H.-G.; Santander, M.; Sarkar, S.; Schatto, K.; Schlenstedt, S.; Schmidt, T.; Schukraft, A.; Schultes, A.; Schulz, O.; Schunck, M.; Seckel, D.; Semburg, B.; Seo, S. H.; Sestayo, Y.; Seunarine, S.; Silvestri, A.; Singh, K.; Slipak, A.; Spiczak, G. M.; Spiering, C.; Stamatikos, M.; Stanev, T.; Stephens, G.; Stezelberger, T.; Stokstad, R. G.; Stoyanov, S.; Strahler, E. A.; Straszheim, T.; Sullivan, G. W.; Swillens, Q.; Taavola, H.; Taboada, I.; Tamburro, A.; Tarasova, O.; Tepe, A.; Ter-Antonyan, S.; Tilav, S.; Toale, P. A.; Toscano, S.; Tosi, D.; Turčan, D.; van Eijndhoven, N.; Vandenbroucke, J.; Van Overloop, A.; van Santen, J.; Voge, M.; Voigt, B.; Walck, C.; Waldenmaier, T.; Wallraff, M.; Walter, M.; Weaver, Ch.; Wendt, C.; Westerhoff, S.; Whitehorn, N.; Wiebe, K.; Wiebusch, C. H.; Wikström, G.; Williams, D. R.; Wischnewski, R.; Wissing, H.; Wolf, M.; Woschnagg, K.; Xu, C.; Xu, X. W.; Yodh, G.; Yoshida, S.; Zarzhitsky, P.
2011-03-01
SN 2008D, a core collapse supernova at a distance of 27 Mpc, was serendipitously discovered by the Swift satellite through an associated X-ray flash. Core collapse supernovae have been observed in association with long gamma-ray bursts and X-ray flashes and a physical connection is widely assumed. This connection could imply that some core collapse supernovae possess mildly relativistic jets in which high-energy neutrinos are produced through proton-proton collisions. The predicted neutrino spectra would be detectable by Cherenkov neutrino detectors like IceCube. A search for a neutrino signal in temporal and spatial correlation with the observed X-ray flash of SN 2008D was conducted using data taken in 2007-2008 with 22 strings of the IceCube detector. Events were selected based on a boosted decision tree classifier trained with simulated signal and experimental background data. The classifier was optimized to the position and a "soft jet" neutrino spectrum assumed for SN 2008D. Using three search windows placed around the X-ray peak, emission time scales from 100-10 000 s were probed. No events passing the cuts were observed in agreement with the signal expectation of 0.13 events. Upper limits on the muon neutrino flux from core collapse supernovae were derived for different emission time scales and the principal model parameters were constrained. While no meaningful limits can be given in the case of an isotropic neutrino emission, the parameter space for a jetted emission can be constrained. Future analyses with the full 86 string IceCube detector could detect up to ~100 events for a core-collapse supernova at 10 Mpc according to the soft jet model.
No evidence of critical slowing down in two endangered Hawaiian honeycreepers
Camp, Richard J.; Reed, J. Michael
2017-01-01
There is debate about the current population trends and predicted short-term fates of the endangered forest birds, Hawai`i Creeper (Loxops mana) and Hawai`i `Ākepa (L. coccineus). Using long-term population size estimates, some studies report forest bird populations as stable or increasing, while other studies report signs of population decline or impending extinction associated with introduced Japanese White-eye (Zosterops japonicus) increase. Reliable predictors of impending population collapse, well before the collapse begins, have been reported in simulations and microcosm experiments. In these studies, statistical indicators of critical slowing down, a phenomenon characterized by longer recovery rates after population size perturbation, are reported to be early warning signals of an impending regime shift observable prior to the tipping point. While the conservation applications of these metrics are commonly discussed, early warning signal detection methods are rarely applied to population size data from natural populations, so their efficacy and utility in species management remain unclear. We evaluated two time series of state-space abundance estimates (1987–2012) from Hakalau Forest National Wildlife Refuge, Hawai`i to test for evidence of early warning signals of impending population collapse for the Hawai`i Creeper and Hawai`i `Ākepa. We looked for signals throughout the time series, and prior to 2000, when white-eye abundance began increasing. We found no evidence for either species of increasing variance, autocorrelation, or skewness, which are commonly reported early warning signals. We calculated linear rather than ordinary skewness because the latter is biased, particularly for small sample sizes. Furthermore, we identified break-points in trends over time for both endangered species, indicating shifts in slopes away from strongly increasing trends, but they were only weakly supported by Bayesian change-point analyses (i.e., no step-wise changes in abundance). The break-point and change-point test results, in addition to the early warning signal analyses, support that the two populations do not appear to show signs of critical slowing down or decline. PMID:29131835
No evidence of critical slowing down in two endangered Hawaiian honeycreepers
Rozek, Jessica C.; Camp, Richard J.; Reed, J. Michael
2017-01-01
There is debate about the current population trends and predicted short-term fates of the endangered forest birds, Hawai`i Creeper (Loxops mana) and Hawai`i `Ākepa (L. coccineus). Using long-term population size estimates, some studies report forest bird populations as stable or increasing, while other studies report signs of population decline or impending extinction associated with introduced Japanese White-eye (Zosterops japonicus) increase. Reliable predictors of impending population collapse, well before the collapse begins, have been reported in simulations and microcosm experiments. In these studies, statistical indicators of critical slowing down, a phenomenon characterized by longer recovery rates after population size perturbation, are reported to be early warning signals of an impending regime shift observable prior to the tipping point. While the conservation applications of these metrics are commonly discussed, early warning signal detection methods are rarely applied to population size data from natural populations, so their efficacy and utility in species management remain unclear. We evaluated two time series of state-space abundance estimates (1987–2012) from Hakalau Forest National Wildlife Refuge, Hawai`i to test for evidence of early warning signals of impending population collapse for the Hawai`i Creeper and Hawai`i `Ākepa. We looked for signals throughout the time series, and prior to 2000, when white-eye abundance began increasing. We found no evidence for either species of increasing variance, autocorrelation, or skewness, which are commonly reported early warning signals. We calculated linear rather than ordinary skewness because the latter is biased, particularly for small sample sizes. Furthermore, we identified break-points in trends over time for both endangered species, indicating shifts in slopes away from strongly increasing trends, but they were only weakly supported by Bayesian change-point analyses (i.e., no step-wise changes in abundance). The break-point and change-point test results, in addition to the early warning signal analyses, support that the two populations do not appear to show signs of critical slowing down or decline.
How Did Ca. 300 Years of Explosive Activity at Kilauea End?
NASA Astrophysics Data System (ADS)
Swanson, D. A.
2013-12-01
Kilauea experienced ~300 years of frequent explosive eruptions following caldera collapse in about 1500 CE, producing the Keanakāko';i Tephra. The first 200 years were dominated by juvenile-rich phreatomagmatic eruptions, and the next 100 years by lithic-rich phreatomagmatic and phreatic explosive events. For most of this time, the caldera was deep enough (≥600 m) to allow magma and hot rock to interact with external water at and below the water table. This situation changed after the deadly 1790 eruption. The first eruption was magmatic, involving high fountaining that deposited pumice across >25 km2 south of the caldera. The pumice is hard to find today; it was mostly eroded away soon after deposition and is found only in protected areas along drainages and next to obstacles. The deposit has a consistent internal stratigraphy regardless of its thickness (maximum of 12 cm): lower third mostly achneliths (Pele's hair and tears), upper two- thirds pumice bombs and lapilli. The fountaining, the first purely magmatic event since reticulite erupted in ca. 1500, probably signifies a rising magma column and early filling of the caldera. The next eruption was phreatic, depositing fine lithic ash a few millimeters thick across >45 km2 south of the caldera. It may record withdrawal of the magma column and collapse of part of the caldera floor to or below the water table. The magma column rose soon thereafter, and its free surface was above the water table for some time. This event is recorded by Pele's hair deposited on the lithic ash across >30 km2 south of the caldera. The hair forms a jackstraw mat <1 mm thick. Nothing coarser than hair is present, so it is probably not a product of tall fountains. An analog might be the open-vent activity at Halema';uma';u today, where spatter from the magma free-surface (a lava lake) produces Pele's hair that blows kilometers downwind, forming a paper-thin deposit that glistens in the sun like golden grain. Phreatic activity followed, depositing small lapilli now embedded in the hair and lithic ash. This was perhaps a vent-opening event for a dominantly phreatomagmatic eruption. The deposit of this eruption, mostly lithic but with scattered fluidal lapilli, is 0.5-2 cm thick and inversely graded across a depositional area of >40 km2 south of the caldera. Mean grain size along the dispersal axis decreases from 7 mm on the rim of the caldera to 2 mm 7 km south of the caldera, where the deposit disappears into forest. This subplinian eruption records interaction of groundwater with both conduit wallrock and magma, probably during renewed collapse. A few ballistic blocks fell near the caldera soon thereafter, recording separate explosive events after the main eruption. The last Keanakāko';i eruption, erupted some time before 1823, was a lava fountain that deposited golden pumice up to 3 m thick west of the caldera. The eruption clearly indicates that the caldera was filling and on its way to its present status. Thus the ca. 300 years of explosive activity ended with a bumpy transition from a deep to a relatively full caldera. The duration of the transition is unknown but shorter than about 30 years. During that time, at least two small collapses interrupted a generally rising magma column, which finally gained the upper hand and culminated in the mostly effusive activity of Kilauea ever since.
Coccolithovirus facilitation of carbon export in the North Atlantic.
Laber, Christien P; Hunter, Jonathan E; Carvalho, Filipa; Collins, James R; Hunter, Elias J; Schieler, Brittany M; Boss, Emmanuel; More, Kuldeep; Frada, Miguel; Thamatrakoln, Kimberlee; Brown, Christopher M; Haramaty, Liti; Ossolinski, Justin; Fredricks, Helen; Nissimov, Jozef I; Vandzura, Rebecca; Sheyn, Uri; Lehahn, Yoav; Chant, Robert J; Martins, Ana M; Coolen, Marco J L; Vardi, Assaf; DiTullio, Giacomo R; Van Mooy, Benjamin A S; Bidle, Kay D
2018-05-01
Marine phytoplankton account for approximately half of global primary productivity 1 , making their fate an important driver of the marine carbon cycle. Viruses are thought to recycle more than one-quarter of oceanic photosynthetically fixed organic carbon 2 , which can stimulate nutrient regeneration, primary production and upper ocean respiration 2 via lytic infection and the 'virus shunt'. Ultimately, this limits the trophic transfer of carbon and energy to both higher food webs and the deep ocean 2 . Using imagery taken by the Moderate Resolution Imaging Spectroradiometer (MODIS) onboard the Aqua satellite, along with a suite of diagnostic lipid- and gene-based molecular biomarkers, in situ optical sensors and sediment traps, we show that Coccolithovirus infections of mesoscale (~100 km) Emiliania huxleyi blooms in the North Atlantic are coupled with particle aggregation, high zooplankton grazing and greater downward vertical fluxes of both particulate organic and particulate inorganic carbon from the upper mixed layer. Our analyses captured blooms in different phases of infection (early, late and post) and revealed the highest export flux in 'early-infected blooms' with sinking particles being disproportionately enriched with infected cells and subsequently remineralized at depth in the mesopelagic. Our findings reveal viral infection as a previously unrecognized ecosystem process enhancing biological pump efficiency.
Genetics Home Reference: familial male-limited precocious puberty
... male-limited precocious puberty Familial male-limited precocious puberty Printable PDF Open All Close All Enable Javascript ... expand/collapse boxes. Description Familial male-limited precocious puberty is a condition that causes early sexual development ...
Marine ice sheet collapse potentially under way for the Thwaites Glacier Basin, West Antarctica.
Joughin, Ian; Smith, Benjamin E; Medley, Brooke
2014-05-16
Resting atop a deep marine basin, the West Antarctic Ice Sheet has long been considered prone to instability. Using a numerical model, we investigated the sensitivity of Thwaites Glacier to ocean melt and whether its unstable retreat is already under way. Our model reproduces observed losses when forced with ocean melt comparable to estimates. Simulated losses are moderate (<0.25 mm per year at sea level) over the 21st century but generally increase thereafter. Except possibly for the lowest-melt scenario, the simulations indicate that early-stage collapse has begun. Less certain is the time scale, with the onset of rapid (>1 mm per year of sea-level rise) collapse in the different simulations within the range of 200 to 900 years. Copyright © 2014, American Association for the Advancement of Science.
2017-10-20
testing unremarkable (’lilble 1) • Repeat exerciBe laryogoacopy found laryngeal edema and no 1LO Noted to have expindory wheezing belt belrd over...DLo/VA 4.l! 187" ) Vocal cord edema or paralysis Paradoxical vocal cord motion Laryngeal stenosls Laryngocele Tonsillar hypertrophy Post nasal
Collective Defense of the Baltic States: A SOF Beginning
2012-03-20
in Baltic’s Region Russian Military Reform . Since the Soviet Union collapsed in 1989, Russia has attempted to re-organize its ineffective post...RIANOVOSTI Online, February 09 2009, http://en.rian.ru/russia/20090209/120055890.html (accessed November 09, 2011). 10 Jim Nichol, Russian Military Reform and
Post-Soviet Moral Education: The Case of Kyrgyzstan
ERIC Educational Resources Information Center
Misco, Thomas; Hamot, Gregory E.
2007-01-01
The Republic of Kyrgyzstan became a free and democratic state after the collapse of the Soviet Union. Since that time, Kyrgyzstan has redefined and renegotiated what education in its society should be. Although numerous internal and external initiatives have sought to reshape Kyrgyzstan's curriculum and instructional strategies, these projects…
Domanski, Michael; Farkouh, Michael E; Zak, Victor; French, John; Alexander, John H; Bochenek, Andrzej; Hamon, Martial; Mahaffey, Kenneth; Puskas, John; Smith, Peter; Shrader, Peter; Fuster, Valentin
2016-12-01
Associations of early creatine phosphokinase-MB (CK-MB) elevation and new Q waves and their association with cardiovascular death (CVD) after coronary artery bypass grafting (CABG) have been reported, but this association has not been studied in a large population of patients with diabetes mellitus. In this study, we examine the association of periprocedural CK-MB elevations and new Q waves with CVD in the Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease trial. Cox proportional hazards regression was used to assess the relation of CK-MB elevations and new Q waves in the first 24 hours after procedure and their relation to CVD; logistic regression was used to assess odds ratios of these variables. Hazard ratios, 95% confidence intervals, and p values associated with Wald chi-square test are reported. CK-MB elevation in first 24 hours after procedure was independently associated with CVD. CVD hazard increased by 6% (p <0.001) with each multiple of CK-MB above the upper reference limit (URL); odds of new post-CABG Q waves increased by a factor of 1.08 (p <0.001); at 7× CK-MB URL, HR was >2. CK-MB URL multiples of 7, 12, and 15 were associated with new Q-wave odds ratios of 9, 16, and 27 times, respectively (p ≤0.001, C-statistic >0.70). New Q waves were independently associated with survival in the multivariate model only when CK-MB was excluded (p = 0.01). In conclusion, independent associations included (1) CVD and early post-CABG CK-MB elevation; (2) new Q waves with early post-CABG CK-MB elevation; (3) CVD with new Q waves only when CK-MB elevation is excluded from analysis. Copyright © 2016 Elsevier Inc. All rights reserved.
Stability of the Early Mars Atmosphere to Collapse into Permanent Polarcaps
NASA Technical Reports Server (NTRS)
Haberle, R. M.; Kahre, M. A.; Wordsworth, R.; Forget, F.
2016-01-01
The presence of a permanent CO2 polar ice cap on Mars has important consequences for the planet's climate system. The heat balance of such a cap, which is determined mainly by atmospheric heat transport, and the downward solar in infrared radiative fluxes, determines its surface temperature, which through the vapor pressure relation sets the mean annual surface pressure. On Mars today, for example, the south residual CO2 cap is present year-round with a mean annual temperature of approximately 145 K which corresponds to a mean annual CO2 vapor pressure of approximately 600 Pa. On early Mars, permanent polar caps are also possible especially since the sun was less luminous 3.5-4.0 Gya. Thus, the existence of permanent polar caps on early Mars is central to understanding the nature of the planets climate system in those ancient times and whether or not the atmosphere might have been capable of sustaining conditions suitable for liquid water flowing over the surface as is indicated in the geological record. Forget et al [1] showed that for present orbital properties atmospheric collapse into permanent polar caps could only be prevented for surface pressures roughly between 500 - 3000 hPa. Though follow-on studies confirm and extend the Forget et al. results [2], the full sensitivity of this "window" of stability has not been explored. There are many factors to consider such the albedo of the caps, dust content of the atmosphere, and the presence of water ice clouds. However, we begin our exploration of the stability of the early Martian atmosphere by focusing on the role of CO2 ice clouds. In some preliminary simulations with the Ames Mars General Circulation Model (GCM) we found that atmospheric collapse depends on assumptions regarding the fate of CO2 ice clouds. If, for example, we assume the clouds immediately fall to the surface, then in some cases collapse is favored. On the other hand if the clouds are allowed to fall and evaporate, collapse can be averted. This implies that CO2 ice cloud microphysics is important to the overall stability of the atmosphere. Though the Ames GCM has a sophisticated CO2 cloud microphysics package that includes nucleation, growth, and sedimentation (see accompanying poster by Kahre et al. [3]), we have implemented a simpler scheme based on the Forget et al. [1] approach to CO2 ice clouds. Our goal is to reproduce and expand their study. The key parameter in this approach is the concentration and vertical distribution of cloud condensation nuclei (CCN), i.e., dust particles. Fewer CCN lead to larger particles which fall faster, while higher CCN concentrations lead to smaller particles and thicker clouds that remain suspended for longer periods of time. We plan to explore the stability of the atmosphere to CCN concentrations and distributions and then assess the capability of thick early atmospheres to loft and distribute dust particles (CCN) around the planet. Thus, our work will shed light on the nature of the coupling between the dust and CO2 cycles and the implications it has for the early Mars climate system.
Lixin Wang; David S. Leigh
2015-01-01
Human activities have become important influences on the fluvial systems of eastern North America since post-colonial settlement. This research identifies post-settlement anthropic signatures in alluvial sediments in the Upper Little Tennessee River, USA. Agricultural and mining activities were scattered and discontinuous in this relatively remote region of...
Capacitive micromachined ultrasonic transducers (CMUTs) with isolation posts.
Huang, Yongli; Zhuang, Xuefeng; Haeggstrom, Edward O; Ergun, A Sanli; Cheng, Ching-Hsiang; Khuri-Yakub, Butrus T
2008-03-01
In this paper, an improved design of a capacitive micromachined ultrasonic transducer (CMUT) is presented. The design improvement aims to address the reliability issues of a CMUT and to extend the device operation beyond the contact (collapse) voltage. The major design novelty is the isolation posts in the vacuum cavities of the CMUT cells instead of full-coverage insulation layers in conventional CMUTs. This eliminates the contact voltage drifting due to charging caused by the insulation layer, and enables repeatable CMUT operation in the post-contact regime. Ultrasonic tests of the CMUTs with isolation posts (PostCMUTs) in air (electrical input impedance and capacitance vs. bias voltage) and immersion (transmission and reception) indicate acoustic performance similar to that obtained from conventional CMUTs while no undesired side effects of this new design is observed.
NASA Astrophysics Data System (ADS)
Froger, Jean-Luc; Famin, Vincent; Cayol, Valérie; Augier, Aurélien; Michon, Laurent; Lénat, Jean-François
2015-04-01
From March 30 to May 1 2007, Piton de la Fournaise, La Réunion Island, experienced a major eruptive crisis, characterized by the largest emitted lava volume (210 × 106 m3) of the 20th and 21st centuries, and by a 340 m deep caldera collapse. The event was captured by InSAR data from the ENVISAT and ALOS-1 satellites. From this data, we computed the EW and vertical components of the displacement that occurred on the entire edifice during the co-eruptive period and in the following months. Our results reveal unusually large and time-dependent displacements of the Central Cone and the Eastern Flank of Piton de la Fournaise, both of which continued to deform for at least a year after the end of the eruption. The analysis of InSAR displacement combined with other geophysical and field observations allows us to propose conceptual models to explain the Central Cone and the Eastern Flank displacements. We propose that the April 2007 caldera collapse induced a sudden decompression of the hydrothermal system, which had been previously pressurized and heated by temporary sealing of its upper part. This sudden decompression resulted in a strong centripetal subsidence. This then decreased exponentially as poro-elastic compaction and creep of the Central Cone propagated from the collapsed rock column to more distal parts of the hydrothermal system. For the Eastern Flank, we propose that the displacement is related to an intrusion within the Grandes Pentes. While propagating to the surface, the intrusion may have encountered a pre-existing structural discontinuity, intruded it and activated it as a detachment surface. It is likely that the detachment slip, by reducing the minimum principal stress close to the summit, allowed the injection of the dyke that fed the brief March 30-31 eruption. Then it may have promoted the migration of magma from the main magma storage zone, beneath the Central Cone, to the distal April 2 eruption site. The EW extensional stress field resulting from the slip of the detachment during the co-eruptive period may have activated a set of normal faults on which aseismic creep controlled the response of the edifice during the post-eruptive period.
Early warning signals of regime shifts in coupled human–environment systems
Bauch, Chris T.; Sigdel, Ram; Pharaon, Joe; Anand, Madhur
2016-01-01
In complex systems, a critical transition is a shift in a system’s dynamical regime from its current state to a strongly contrasting state as external conditions move beyond a tipping point. These transitions are often preceded by characteristic early warning signals such as increased system variability. However, early warning signals in complex, coupled human–environment systems (HESs) remain little studied. Here, we compare critical transitions and their early warning signals in a coupled HES model to an equivalent environment model uncoupled from the human system. We parameterize the HES model, using social and ecological data from old-growth forests in Oregon. We find that the coupled HES exhibits a richer variety of dynamics and regime shifts than the uncoupled environment system. Moreover, the early warning signals in the coupled HES can be ambiguous, heralding either an era of ecosystem conservationism or collapse of both forest ecosystems and conservationism. The presence of human feedback in the coupled HES can also mitigate the early warning signal, making it more difficult to detect the oncoming regime shift. We furthermore show how the coupled HES can be “doomed to criticality”: Strategic human interactions cause the system to remain perpetually in the vicinity of a collapse threshold, as humans become complacent when the resource seems protected but respond rapidly when it is under immediate threat. We conclude that the opportunities, benefits, and challenges of modeling regime shifts and early warning signals in coupled HESs merit further research. PMID:27815533
NASA Astrophysics Data System (ADS)
Smith, Victoria C.; Isaia, Roberto; Engwell, Sam L.; Albert, Paul. G.
2016-06-01
The Campanian Ignimbrite eruption dispersed ash over much of the central eastern Mediterranean Sea and eastern Europe. The eruption started with a Plinian phase that was followed by a series of pyroclastic density currents (PDCs) associated with the collapse of the Plinian column and the caldera. The glass compositions of the deposits span a wide geochemical range, but the Plinian fallout and PDCs associated with column collapse, the Lower Pumice Flow, only erupted the most evolved compositions. The later PDCs, the Breccia Museo and Upper Pumice Flow, erupted during and after caldera collapse, tap a less evolved component, and intermediate compositions that represent mixing between the end-members. The range of glass compositions in the Campanian Ignimbrite deposits from sites across the central and eastern Mediterranean Sea allow us to trace the dispersal of the different phases of this caldera-forming eruption. We map the fallout from the Plinian column and the plumes of fine material associated with the PDCs (co-PDCs) across the entire dispersal area. This cannot be done using the usual grain-size methods as deposits in these distal regions do not retain characteristics that allow attribution to either the Plinian or co-PDC phases. The glass compositions of the tephra at ultra-distal sites (>1500 km from the vent) match those of the uppermost PDC units, suggesting that most of the ultra-distal dispersal was associated with the late co-PDC plume that was generated during caldera collapse.
NASA Astrophysics Data System (ADS)
Han, Rui; Zhang, A.-Man; Li, Shuai; Zong, Zhi
2018-04-01
Two-bubble interaction is the most fundamental problem in multi-bubbles dynamics, which is crucial in many practical applications involving air-gun arrays and underwater explosions. In this paper, we experimentally and numerically investigate coalescence, collapse, and rebound of non-buoyant bubble pairs below a rigid wall. Two oscillating vapor bubbles with similar size are generated simultaneously near a rigid wall in axisymmetric configuration using the underwater electric discharge method, and the physical process is captured by a high-speed camera. Numerical simulations are conducted based on potential flow theory coupled with the boundary integral method. Our numerical results show excellent agreement with the experimental data until the splashing of the jet impact sets in. With different ranges of γbw (the dimensionless distance between the rigid wall and the nearest bubble center), the interaction between the coalesced bubble and the rigid wall is divided into three types, i.e., "weak," "intermediate," and "strong." As γbw decreases, the contact point of the two axial jets migrates toward the wall. In "strong interaction" cases, only an upward jet towards the upper rigid wall forms and a secondary jet with a larger width appears at the base of the first jet. The collapsing coalesced bubble in a toroidal form splits into many smaller bubbles due to the instabilities and presents as bubble clouds during the rebounding phase, which may lead to a weakened pressure wave because the focusing energy associated with the collapsing bubble is disintegrated.
The predictive value of drug-induced sleep endoscopy for CPAP titration in OSA patients.
Lan, Ming-Chin; Hsu, Yen-Bin; Lan, Ming-Ying; Huang, Yun-Chen; Kao, Ming-Chang; Huang, Tung-Tsun; Chiu, Tsan-Jen; Yang, Mei-Chen
2017-12-15
The aim of this study was to identify possible upper airway obstructions causing a higher continuous positive airway pressure (CPAP) titration level, utilizing drug-induced sleep endoscopy (DISE). A total of 76 patients with obstructive sleep apnea (OSA) underwent CPAP titration and DISE. DISE findings were recorded using the VOTE classification system. Polysomnographic (PSG) data, anthropometric variables, and patterns of airway collapse during DISE were analyzed with CPAP titration levels. A significant association was found between the CPAP titration level and BMI, oxygen desaturation index (ODI), apnea-hypopnea index (AHI), and neck circumference (NC) (P < 0.001, P < 0.001, P < 0.001, and P < 0.001, respectively, by Spearman correlation). Patients with concentric collapse of the velum or lateral oropharyngeal collapse were associated with a significantly higher CPAP titration level (P < 0.001 and P = 0.043, respectively, by nonparametric Mann-Whitney U test; P < 0.001 and P = 0.004, respectively, by Spearman correlation). No significant association was found between the CPAP titration level and any other collapse at the tongue base or epiglottis. By analyzing PSG data, anthropometric variables, and DISE results with CPAP titration levels, we can better understand possible mechanisms resulting in a higher CPAP titration level. We believe that the role of DISE can be expanded as a tool to identify the possible anatomical structures that may be corrected by oral appliance therapy or surgical intervention to improve CPAP compliance.
Constraining high-energy neutrino emission from choked jets in stripped-envelope supernovae
NASA Astrophysics Data System (ADS)
Senno, Nicholas; Murase, Kohta; Mészáros, Peter
2018-01-01
There are indications that γ-ray dark objects such as supernovae (SNe) with choked jets, and the cores of active galactic nuclei may contribute to the diffuse flux of astrophysical neutrinos measured by the IceCube observatory. In particular, stripped-envelope SNe have received much attention since they are capable of producing relativistic jets and could explain the diversity in observations of collapsar explosions (e.g., gamma-ray bursts (GRBs), low-luminosity GRBs, and Type Ibc SNe). We use an unbinned maximum likelihood method to search for spatial and temporal coincidences between Type Ibc core-collapse SNe, which may harbor a choked jet, and muon neutrinos from a sample of IceCube up-going track-like events measured from May 2011–May 2012. In this stacking analysis, we find no significant deviation from a background-only hypothesis using one year of data, and are able to place upper limits on the total amount of isotropic equivalent energy that choked jet core-collapse SNe deposit in cosmic rays Script Ecr and the fraction of core-collapse SNe which have a jet pointed towards Earth fjet. This analysis can be extended with yet to be made public IceCube data, and the increased amount of optically detected core-collapse SNe discovered by wide field-of-view surveys such as the Palomar Transient Factory and All-Sky Automated Survey for Supernovae. The choked jet SNe/high-energy cosmic neutrino connection can be more tightly constrained in the near future.
Finn, Carol A.; Deszcz-Pan, Maria; Ball, Jessica L.; Bloss, Benjamin J.; Minsley, Burke J.
2018-01-01
Water-saturated hydrothermal alteration reduces the strength of volcanic edifices, increasing the potential for catastrophic sector collapses that can lead to far traveled and destructive debris flows. Intense hydrothermal alteration significantly lowers the resistivity and magnetization of volcanic rock and therefore hydrothermally altered rocks can be identified with helicopter electromagnetic and magnetic measurements. Geophysical models constrained by rock properties and geologic mapping show that intensely altered rock is restricted to two small (500 m diameter), >150 m thick regions around Sherman Crater and Dorr Fumarole Field at Mount Baker, Washington. This distribution of alteration contrasts with much thicker and widespread alteration encompassing the summits of Mounts Adams and Rainier prior to the 5600 year old Osceola collapse, which is most likely due to extreme erosion and the limited duration of summit magmatism at Mount Baker. In addition, the models suggest that the upper ~300 m of rock contains water which could help to lubricate potential debris flows. Slope stability modeling incorporating the geophysically modeled distribution of alteration and water indicates that the most likely and largest (~0.1 km3) collapses are from the east side of Sherman Crater. Alteration at Dorr Fumarole Field raises the collapse hazard there, but not significantly because of its lower slope angles. Geochemistry and analogs from other volcanoes suggest a model for the edifice hydrothermal system.
NASA Astrophysics Data System (ADS)
Natta, A.
Contents 1 Introduction 2 Collapse of molecular cores 2.1 Giant molecular clouds and cores 2.2 Conditions for collapse 2.3 Free-fall collapse 2.4 Collapse of an isothermal sphere of gas 2.5 Collapse of a slowly rotating core 3 Observable properties of protostars 3.1 Evidence of infall from molecular line profiles 3.2 SEDs of protostars 3.3 The line spectrumof a protostar 4 Protostellar and pre-main-sequence evolution 4.1 The protostellar phase 4.2 Pre-main-sequence evolution 4.3 The birthline 5 Circumstellar disks 5.1 Accretion disks 5.2 Properties of steady accretion disks 5.3 Reprocessing disks 5.4 Disk-star interaction 6 SEDs of disks 6.1 Power-law disks 6.2 Long-wavelength flux and disk mass 6.3 Comparison with TTS observations: Heating mechanism 7 Disk properties from observations 7.1 Mass accretion rate 7.2 Inner radius 7.3 Masses 7.4 Sizes 8 Disk lifetimes 8.1 Ground-based near and mid-infrared surveys 8.2 Mid-infrared ISOCAMsurveys 8.3 ISOPHOT 60 microm survey 8.4 Surveys at millimeter wavelengths 9 Disk evolution 9.1 Can we observe the early planet formation phase? 9.2 Evidence for grain growth 9.3 Evidence of planetesimals 9.4 Where is the diskmass? 10 Secondary or debris disks 11 Summary
NASA Astrophysics Data System (ADS)
Wang, Jia-Min; Wu, Fu-Yuan; Rubatto, Daniela; Liu, Kai; Zhang, Jin-Jiang; Liu, Xiao-Chi
2018-04-01
Reconstructing the evolution of Gneiss domes within orogenic belts poses challenges because domes can form in a variety of geodynamic settings and by multiple doming mechanisms. For the North Himalayan gneiss domes (NHGD), it is debated whether they formed during shortening, extension or collapse of the plateau, and what is the spatial and temporal relationship of magmatism, metamorphism and deformation. This study investigates the Yardoi dome in southern Tibet using field mapping, petrography, phase equilibria modelling and new monazite ages. The resulting P-T-time-deformation-magmatism path for the first time reveals the spatial and temporal relationship of metamorphism, deformation and magmatism in the Yardoi dome: a) the dome mantle recorded prograde loading to kyanite-grade Barrovian metamorphic conditions of 650 ± 30 °C and 9 ± 1 kbar (M2) in the Early Miocene (18-17 Ma); b) the main top-to-the-north deformation fabric (D2) formed syn- to post-peak-metamorphism; c) the emplacement of leucorgranites related to doming is syn-metamorphism at 19-17 Ma. The link between the detachment shear zone in the Yardoi dome and the South Tibetan detachment system (STDS) is confirmed. By comparing with orogen-scale tectonic processes in the Himalaya, we suggest that north-south extension in a convergent geodynamic setting during Early Miocene accounts for formation of the Yardoi dome. In a wider tectonic context, the Early Miocene rapid exhumation of deep crustal rocks was contemporaneous with the rapid uplift of southern Tibet and the Himalayan orogen.
An object-oriented model of the cardiopulmonary system with emphasis on the gravity effect.
Chuong Ngo; Herranz, Silvia Briones; Misgeld, Berno; Vollmer, Thomas; Leonhardt, Steffen
2016-08-01
We introduce a novel comprehensive model of the cardiopulmonary system with emphasis on perfusion and ventilation distribution along the vertical thorax axis under the gravity effect. By using an object-oriented environment, the complex physiological system can be represented by a network of electrical, lumped-element compartments. The lungs are divided into three zones: upper, middle, and lower zone. Blood flow increases with the distance from the apex to the base of the lungs. The upper zone is characterized by a complete collapse of the pulmonary capillary vasculature; thus, there is no flow in this zone. The second zone has a "waterfall effect" where the blood flow is determined by the difference between the pulmonary-arterial and alveolar pressures. At resting position, the upper lobes of the lungs are more expanded than the middle and lower lobes. However, during spontaneous breathing, ventilation is nonuniform with more air entering the lower lobes than the middle and upper lobes. A simulative model of the complete system is developed which shows results in good agreement with the literature.
Ortega-Hernández, Javier
2016-02-01
The ever-increasing number of studies that address the origin and evolution of Euarthropoda - whose extant representatives include chelicerates, myriapods, crustaceans and hexapods - are gradually reaching a consensus with regard to the overall phylogenetic relationships of some of the earliest representatives of this phylum. The stem-lineage of Euarthropoda includes numerous forms that reflect the major morphological transition from a lobopodian-type to a completely arthrodized body organization. Several methods of classification that aim to reflect such a complex evolutionary history have been proposed as a consequence of this taxonomic diversity. Unfortunately, this has also led to a saturation of nomenclatural schemes, often in conflict with each other, some of which are incompatible with cladistic-based methodologies. Here, I review the convoluted terminology associated with the classification of stem-group Euarthropoda, and propose a synapomorphy-based distinction that allows 'lower stem-Euarthropoda' (e.g. lobopodians, radiodontans) to be separated from 'upper stem-Euarthropoda' (e.g. fuxianhuiids, Cambrian bivalved forms) in terms of the structural organization of the head region and other aspects of overall body architecture. The step-wise acquisition of morphological features associated with the origins of the crown-group indicate that the node defining upper stem-Euarthropoda is phylogenetically stable, and supported by numerous synapomorphic characters; these include the presence of a deutocerebral first appendage pair, multisegmented head region with one or more pairs of post-ocular differentiated limbs, complete body arthrodization, posterior-facing mouth associated with the hypostome/labrum complex, and post-oral biramous arthropodized appendages. The name 'Deuteropoda' nov. is proposed for the scion (monophyletic group including the crown-group and an extension of the stem-group) that comprises upper stem-Euarthropoda and Euarthropoda. A brief account of common terminological inaccuracies in recent palaeontological studies evinces the utility of Deuteropoda nov. as a reference point for discussing aspects of early euarthropod phylogeny. © 2014 Cambridge Philosophical Society.
2011-11-10
Scientists are simulating how the very first stars in our universe were born. The stars we see today formed out of collapsing clouds of gas and dust. In the very early universe, however, the stars had fewer ingredients available.
Obstructive sleep apnea syndrome: An important piece in the puzzle of cardiovascular risk factors.
Costa, Cátia; Santos, Beatriz; Severino, Davide; Cabanelas, Nuno; Peres, Marisa; Monteiro, Isabel; Leal, Margarida
2015-01-01
The obstructive sleep apnea syndrome (OSA) is a clinical entity characterized by recurring episodes of apnea and/or hypopnea during sleep, due to a total or partial collapse, respectively, of the upper airway. This collapse originates a set of pathophysiological changes that determine the appearance of several cardiovascular complications. OSA contributes for the development of hypertension, heart failure, arrhythmias and coronary heart disease. Nowadays it is recognized to be an important public health problem, taking into account not just its repercussions but also its prevalence, since the main risk factor for the disease is obesity, a growing problem worldwide, both in developed and developing countries. The present review summarizes the current knowledge about OSA, as regards its definition, pathophysiology, clinical manifestations, diagnosis, cardiovascular effects and treatment. Copyright © 2014 Sociedad Española de Arteriosclerosis. Published by Elsevier España. All rights reserved.
NASA Technical Reports Server (NTRS)
1992-01-01
The Magellan spacecraft has observed remnant landslide deposits apparently resulting from the collapse of volcanic structures. This image, centered at 45.2 degrees south latitude, 201.4 degrees east longitude, shows a collapse deposit 70 kilometers (43 miles) across. The bright, highly textured deposit near the center of the image probably consists of huge blocks of fractured volcanic rock, many as large as several hundred meters across. A remnant of the volcano itself, about 20 kilometers (12.4 miles) across, is seen at the center of the image. The distorted radar appearance of the volcano is a result of extremely steep slopes on the 'scars' from which the landslide material originated. A field of numerous small volcanic domes can be seen in the northern half of the image. The bright irregular lineaments trending to the north-northwest are ridges caused by regional tectonic deformation of the upper layers of the Venusian crust.
John, D.A.; Sisson, T.W.; Breit, G.N.; Rye, R.O.; Vallance, J.W.
2008-01-01
Hydrothermal alteration at Mount Rainier waxed and waned over the 500,000-year episodic growth of the edifice. Hydrothermal minerals and their stable-isotope compositions in samples collected from outcrop and as clasts from Holocene debris-flow deposits identify three distinct hypogene argillic/advanced argillic hydrothermal environments: magmatic-hydrothermal, steam-heated, and magmatic steam (fumarolic), with minor superimposed supergene alteration. The 3.8??km3 Osceola Mudflow (5600??y BP) and coeval phreatomagmatic F tephra contain the highest temperature and most deeply formed hydrothermal minerals. Relatively deeply formed magmatic-hydrothermal alteration minerals and associations in clasts include quartz (residual silica), quartz-alunite, quartz-topaz, quartz-pyrophyllite, quartz-dickite/kaolinite, and quartz-illite (all with pyrite). Clasts of smectite-pyrite and steam-heated opal-alunite-kaolinite are also common in the Osceola Mudflow. In contrast, the Paradise lahar, formed by collapse of the summit or near-summit of the edifice at about the same time, contains only smectite-pyrite and near-surface steam-heated and fumarolic alteration minerals. Younger debris-flow deposits on the west side of the volcano (Round Pass and distal Electron Mudflows) contain only low-temperature smectite-pyrite assemblages, whereas the proximal Electron Mudflow and a < 100??y BP rock avalanche on Tahoma Glacier also contain magmatic-hydrothermal alteration minerals that are exposed in the avalanche headwall of Sunset Amphitheater, reflecting progressive incision into deeper near-conduit alteration products that formed at higher temperatures. The pre-Osceola Mudflow alteration geometry is inferred to have consisted of a narrow feeder zone of intense magmatic-hydrothermal alteration limited to near the conduit of the volcano, which graded outward to more widely distributed, but weak, smectite-pyrite alteration within 1??km of the edifice axis, developed chiefly in porous breccias. The edifice was capped by a steam-heated alteration zone, most of which resulted from condensation of fumarolic vapor and oxidation of H2S in the unsaturated zone above the water table. Weakly developed smectite-pyrite alteration extended into the west and east flanks of the edifice, spatially associated with dikes that are localized in those sectors; other edifice flanks lack dikes and associated alteration. The Osceola collapse removed most of the altered core and upper east flank of the volcano, but intensely altered rocks remain on the uppermost west flank. Major conclusions of this study are that: (1) Hydrothermal-mineral assemblages and distributions at Mount Rainier can be understood in the framework of hydrothermal processes and environments developed from studies of ore deposits formed in analogous settings. (2) Frequent eruptions supplied sufficient hot magmatic fluid to alter the upper interior of the volcano hydrothermally, despite the consistently deep (??? 8??km) magma reservoir which may have precluded formation of economic mineral deposits within or at shallow depths beneath Mount Rainier. The absence of indicator equilibrium alteration-mineral assemblages in the debris flows that effectively expose the volcano to a depth of 1-1.5??km also suggests a low potential for significant high-sulfidation epithermal or porphyry-type mineral deposits at depth. (3) Despite the long and complex history of the volcano, intensely altered collapse-prone rocks were spatially restricted to near the volcano's conduit system and summit, and short distances onto the upper east and west flanks, due to the necessary supply of reactive components carried by ascending magmatic fluids. (4) Intensely altered rocks were removed from the summit, east flank, and edifice interior by the Osceola collapse, but remain on the upper west flank in the Sunset Amphitheater area and present a continuing collapse hazard. (5) Visually conspicuous rocks on the lower east and mid-to-lower
NASA Astrophysics Data System (ADS)
Charbonnier, S. J.; Gertisser, R.
2009-10-01
We present Titan2D simulations of two well-characterized block-and-ash flow (BAF) events of the 2006 eruption of Merapi (Java, Indonesia) that affected the Gendol valley on the volcano’s southern flank and adjacent, densely populated interfluve (non-valley) areas: (1) a single dome-collapse event to the south that generated one of the smaller, post-June 14 flows and (2) a sustained, multiple dome-collapse event, also directed to the south, that produced the largest flows of the 2006 eruption emplaced in the afternoon of June 14. Using spatially varying bed friction angles, Titan2D is capable of reproducing the paths, velocities, runout distance, areas covered and deposited volumes of these flows over highly complex topography. The model results provide the basis for estimating the areas and levels of hazards associated with BAFs generated during relatively short as well as prolonged dome-collapse periods and guidance during future eruptive crises at Merapi.
Sequential megafaunal collapse in the North Pacific Ocean: An ongoing legacy of industrial whaling?
Springer, A.M.; Estes, J.A.; Van Vliet, Gus B.; Williams, T.M.; Doak, D.F.; Danner, E.M.; Forney, K.A.; Pfister, B.
2003-01-01
Populations of seals, sea lions, and sea otters have sequentially collapsed over large areas of the northern North Pacific Ocean and southern Bering Sea during the last several decades. A bottom-up nutritional limitation mechanism induced by physical oceanographic change or competition with fisheries was long thought to be largely responsible for these declines. The current weight of evidence is more consistent with top-down forcing. Increased predation by killer whales probably drove the sea otter collapse and may have been responsible for the earlier pinniped declines as well. We propose that decimation of the great whales by post-World War II industrial whaling caused the great whales' foremost natural predators, killer whales, to begin feeding more intensively on the smaller marine mammals, thus "fishing-down" this element of the marine food web. The timing of these events, information on the abundance, diet, and foraging behavior of both predators and prey, and feasibility analyses based on demographic and energetic modeling are all consistent with this hypothesis.
Sequential megafaunal collapse in the North Pacific Ocean: An ongoing legacy of industrial whaling?
Springer, A. M.; Estes, J. A.; van Vliet, G. B.; Williams, T. M.; Doak, D. F.; Danner, E. M.; Forney, K. A.; Pfister, B.
2003-01-01
Populations of seals, sea lions, and sea otters have sequentially collapsed over large areas of the northern North Pacific Ocean and southern Bering Sea during the last several decades. A bottom-up nutritional limitation mechanism induced by physical oceanographic change or competition with fisheries was long thought to be largely responsible for these declines. The current weight of evidence is more consistent with top-down forcing. Increased predation by killer whales probably drove the sea otter collapse and may have been responsible for the earlier pinniped declines as well. We propose that decimation of the great whales by post-World War II industrial whaling caused the great whales' foremost natural predators, killer whales, to begin feeding more intensively on the smaller marine mammals, thus “fishing-down” this element of the marine food web. The timing of these events, information on the abundance, diet, and foraging behavior of both predators and prey, and feasibility analyses based on demographic and energetic modeling are all consistent with this hypothesis. PMID:14526101
Why herd size matters - mitigating the effects of livestock crashes.
Næss, Marius Warg; Bårdsen, Bård-Jørgen
2013-01-01
Analysing the effect of pastoral risk management strategies provides insights into a system of subsistence that have persevered in marginal areas for hundreds to thousands of years and may shed light into the future of around 200 million households in the face of climate change. This study investigated the efficiency of herd accumulation as a buffer strategy by analysing changes in livestock holdings during an environmental crisis in the Saami reindeer husbandry in Norway. We found a positive relationship between: (1) pre- and post-collapse herd size; and (2) pre-collapse herd size and the number of animals lost during the collapse, indicating that herd accumulation is an effective but costly strategy. Policies that fail to incorporate the risk-beneficial aspect of herd accumulation will have a limited effect and may indeed fail entirely. In the context of climate change, official policies that incorporate pastoral risk management strategies may be the only solution for ensuring their continued existence.
Unveiling early black holes with JWST
NASA Astrophysics Data System (ADS)
Natarajan, Priyamvada
The formation of direct collapse black hole seeds with masses ~104 - 105 ~M⊙ could help explain the assembly of supermassive black holes powering high redshift quasars. Conditions conducive to the formation of these massive initial seeds exist at high redshift. Halos hosting these massive seeds merge promptly with a nearby galaxy. These early stage mergers at high redshift produce a new class of transient galaxies that contain an accreting black hole that is over-massive compared to the newly acquired stellar component - Obese Black hole Galaxies (OBGs). During this phase, the accretion luminosity of the direct collapse black hole seed exceeds that of the acquired stellar component. Here we calculate the multi-wavelength spectrum of this short-lived OBG stage, and show that there exist unique observational signatures in long wavelengths spanning near, mid to far-infrared that should be detectable by instruments aboard the upcoming James Webb Space Telescope (JWST).
Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms
Kubin, Leszek
2017-01-01
Upper airway muscles subserve many essential for survival orofacial behaviors, including their important role as accessory respiratory muscles. In the face of certain predisposition of craniofacial anatomy, both tonic and phasic inspiratory activation of upper airway muscles is necessary to protect the upper airway against collapse. This protective action is adequate during wakefulness, but fails during sleep which results in recurrent episodes of hypopneas and apneas, a condition known as the obstructive sleep apnea syndrome (OSA). Although OSA is almost exclusively a human disorder, animal models help unveil the basic principles governing the impact of sleep on breathing and upper airway muscle activity. This article discusses the neuroanatomy, neurochemistry, and neurophysiology of the different neuronal systems whose activity changes with sleep-wake states, such as the noradrenergic, serotonergic, cholinergic, orexinergic, histaminergic, GABAergic and glycinergic, and their impact on central respiratory neurons and upper airway motoneurons. Observations of the interactions between sleep-wake states and upper airway muscles in healthy humans and OSA patients are related to findings from animal models with normal upper airway, and various animal models of OSA, including the chronic-intermittent hypoxia model. Using a framework of upper airway motoneurons being under concurrent influence of central respiratory, reflex and state-dependent inputs, different neurotransmitters, and neuropeptides are considered as either causing a sleep-dependent withdrawal of excitation from motoneurons or mediating an active, sleep-related inhibition of motoneurons. Information about the neurochemistry of state-dependent control of upper airway muscles accumulated to date reveals fundamental principles and may help understand and treat OSA. PMID:27783860
Looking for early black holes signatures in the anisotropies of Cosmic backgrounds
NASA Astrophysics Data System (ADS)
Cappelluti, Nico
2016-04-01
We currently do not know how Super Massive Black Holes are seeded and grow to form the observed massive QSO at z~7. This is puzzling, because at that redshift the Universe was still too young to allow the growth of such massive black holes from stellar remnant black hole seeds. Theoretical models, taking into account the paucity of metals in the early Universe, explain this by invoking the formation of massive black holes seeds at z>10 as Direct Collapse Black holes of remnants of dead POPIII stars. As of today we cannot claim any detection of any high-z (z>7) black hole in their early stage of life. However, our recent measures of the arcminute scale joint fluctuations of the Cosmic X-ray Background and the Cosmic Infrared Background by Chandra and Spitzer can be explained by a population of highly absorbed z>10 Direct Collapse Black Holes.I will review the recent discoveries obtained with different instruments and by different teams and critically discuss these findings and the interpretations.
Mangus, Richard S; Fridell, Jonathan A; Kubal, Chandrashekhar A; Davis, Jason P; Tector, A Joseph
2015-02-01
Serum alanine aminotransferase (ALT) levels are frequently elevated with liver injury and such elevations are common in deceased organ donors. The impact of this injury on early liver allograft function has not been well described. This study analyses the immediate function and 1-year graft and patient survival for liver allografts stratified by peak serum ALT levels in the deceased donor. The on-site organ procurement records for 1348 consecutive deceased liver donors were reviewed (2001–2011). Serum ALT was categorized into three study groups: normal/mild elevation, 0–499 μ/L; moderate elevation, 500–999 μ/L (>10× upper limit of normal) and severe elevation, ≥1000 μ/L (>20× upper limit of normal). Outcomes included early graft function and graft loss, and 1-year graft and patient survival. Distribution of subjects included: normal/mild, 1259 (93%); moderate, 34 (3%) and severe, 55 (4%). Risk of 30-day graft loss for the three study groups was: 72 (6%), 3 (9%) and 3 (6%) (P = 0.74). Graft and patient survival at 1 year for the three groups was: normal/mild, 1031 (87%), 1048 (88%); moderate, 31 (91%), 31 (91%) and severe, 43 (88%), 44 (90%) (P = 0.71, 0.79). Cox proportional hazards modelling of survival while controlling for donor age and recipient model for end-stage liver disease score (MELD) demonstrates no statistically significant difference among the three study groups. This study demonstrates clinical equivalence in early graft function and 1-year graft and patient survival for donor livers with varying peak levels of serum ALT. These donor allografts may, therefore, be utilized successfully.
Non-variceal upper gastrointestinal bleeding: Rescue treatment with a modified cyanoacrylate.
Grassia, Roberto; Capone, Pietro; Iiritano, Elena; Vjero, Katerina; Cereatti, Fabrizio; Martinotti, Mario; Rozzi, Gabriele; Buffoli, Federico
2016-12-28
To evaluate the safety and efficacy of a modified cyanoacrylate [N-butyl-2-cyanoacrylate associated with methacryloxysulfolane (NBCA + MS)] to treat non-variceal upper gastrointestinal bleeding (NV-UGIB). In our retrospective study we took into account 579 out of 1177 patients receiving endoscopic treatment for NV-UGIB admitted to our institution from 2008 to 2015; the remaining 598 patients were treated with other treatments. Initial hemostasis was not achieved in 45 of 579 patients; early rebleeding occurred in 12 of 579 patients. Thirty-three patients were treated with modified cyanoacrylate: 27 patients had duodenal, gastric or anastomotic ulcers, 3 had post-mucosectomy bleeding, 2 had Dieulafoy's lesions, and 1 had duodenal diverticular bleeding. Of the 45 patients treated endoscopically without initial hemostasis or with early rebleeding, 33 (76.7%) were treated with modified cyanoacrylate glue, 16 (37.2%) underwent surgery, and 3 (7.0%) were treated with selective transarterial embolization. The mean age of patients treated with NBCA + MS (23 males and 10 females) was 74.5 years. Modified cyanoacrylate was used in 24 patients during the first endoscopy and in 9 patients experiencing rebleeding. Overall, hemostasis was achieved in 26 of 33 patients (78.8%): 19 out of 24 (79.2%) during the first endoscopy and in 7 out of 9 (77.8%) among early rebleeders. Two patients (22.2%) not responding to cyanoacrylate treatment were treated with surgery or transarterial embolization. One patient had early rebleeding after treatment with cyanoacrylate. No late rebleeding during the follow-up or complications related to the glue injection were recorded. Modified cyanoacrylate solved definitively NV-UGIB after failure of conventional treatment. Some reported life-threatening adverse events with other formulations, advise to use it as last option.
Linking magmatism with collision in an accretionary orogen
Li, Shan; Chung, Sun-Lin; Wilde, Simon A.; Wang, Tao; Xiao, Wen-Jiao; Guo, Qian-Qian
2016-01-01
A compilation of U-Pb age, geochemical and isotopic data for granitoid plutons in the southern Central Asian Orogenic Belt (CAOB), enables evaluation of the interaction between magmatism and orogenesis in the context of Paleo-Asian oceanic closure and continental amalgamation. These constraints, in conjunction with other geological evidence, indicate that following consumption of the ocean, collision-related calc-alkaline granitoid and mafic magmatism occurred from 255 ± 2 Ma to 251 ± 2 Ma along the Solonker-Xar Moron suture zone. The linear or belt distribution of end-Permian magmatism is interpreted to have taken place in a setting of final orogenic contraction and weak crustal thickening, probably as a result of slab break-off. Crustal anatexis slightly post-dated the early phase of collision, producing adakite-like granitoids with some S-type granites during the Early-Middle Triassic (ca. 251–245 Ma). Between 235 and 220 Ma, the local tectonic regime switched from compression to extension, most likely caused by regional lithospheric extension and orogenic collapse. Collision-related magmatism from the southern CAOB is thus a prime example of the minor, yet tell-tale linking of magmatism with orogenic contraction and collision in an archipelago-type accretionary orogen. PMID:27167207
NASA Astrophysics Data System (ADS)
Marcon, V.; Gu, X.; Brantley, S. L.
2017-12-01
Life on Earth relies on the breakdown of impermeable bedrock into porous weathered rock to release nutrients and open pathways for gases and fluids to move through the subsurface. Serpentinites, though rare, are found across the globe and often have thin soils. Few studies have evaluated how porosity, a first order control on weathering, evolves from unweathered serpentinite bedrock to the soil. In this study, we evaluated weathering of serpentinites from bedrock to soil along a ridgetop in Nottingham Park, PA. A suite of geochemical analyses were used to determine chemical and physical changes during weathering. We used neutron scattering to measure pores 2nm to 20 microns in size (referred to here as nanoporosity). As this serpentinite weathers, small pores ( 1nm in diameter) are occluded and total nanoporosity and pore connectivity decrease throughout the weathered rock. Specifically, total nanoporosity decreases from 10% in the unweathered parent material to 5% in the weathered rock. However, in the upper meter of the profile, total nanoporosity increases as Fe, Mg, Mn, Si, Ni, Cr, and V are depleted. Additionally, bulk density and strain calculations suggest total volume expansion throughout the weathered rock followed by volume collapse in the upper 0.5m of the profile. We propose that low temperature reactions alter olivine in the parent material to serpentine minerals at the parent-weathered rock interface, resulting in a volume expansion and the loss of nanopores 1-100nm in size in this weathered rock zone. Volume expansion has long been reported to occur during low temperature serpentinization. We also infer that this loss of porosity limits the infiltration of reactive meteoric fluids into the deeper rock material and restricts the depth of regolith development. Following low temperature serpentinization, serpentine minerals (e.g. antigorite and lizardite) dissolve higher in the weathered rock. Because serpentinite rocks lack a non-reactive mineral such as quartz to provide supportive skeleton in the regolith, dissolution ultimately leads to collapse in the upper meter of the profile. The evolution of porosity in this profile can help explain why serpentinite regolith is characteristically thin to non-existent in the Piedmont: thin regolith occurs because of porosity occlusion as well as collapse.
Evaluating the Recession's Impact on State School Finance Systems
ERIC Educational Resources Information Center
Baker, Bruce D.
2014-01-01
The Great Recession's effect on state school finance systems was unlike previous downturns in the early 1990s and early 2000s in that it: a) involved a greater loss of taxable income in many states, thus greater loss to state general fund revenues, b) also involved a substantial collapse of housing markets and related reduction or at least…
Pawanindra, Lal; Vindal, Anubhav; Midha, Manoj; Nagpal, Prashant; Manchanda, Alpana; Chander, Jagdish
2015-10-01
Pre- and post-operative stomach volumes can be important determinants for effectiveness of laparoscopic sleeve gastrectomy (LSG) in causing weight loss. There is little existing data on the volumes of stomach preoperatively and that excised during LSG. This study was designed to evaluate the change in gastric volume after LSG using multi-detector CT and to correlate it with early post-operative weight loss. Twenty consecutive patients with BMI ≥ 40 kg/m(2) and medical comorbidities underwent LSG between October 2011 and October 2013 and were analysed prospectively. The pre-operative stomach volume was measured by MDCT done 1-3 days before the surgery. LSG was performed in the standard manner using a 36F bougie. The volume of excised stomach was measured by distending the specimen with saline. MDCT of the upper abdomen was repeated 3 months postoperatively to calculate the gastric sleeve volume. Weight loss and resolution of comorbidities were documented. The mean pre-operative weight of patients was 123.90 kg, and the mean pre-operative stomach volume on MDCT was 1,067 ml. The stomach volume on pre-operative MDCT correlated with pre-operative weight and BMI. The mean volume of the excised stomach was 859 ml when measured by distension of the specimen and 850 ml on MDCT. After 3 months post surgery, the mean volume of gastric sleeve on MDCT was 217 ml, and the mean weight of the patients was 101.22 kg. The volume of the excised stomach calculated by MDCT correlated with the weight loss achieved 3 months postoperatively. However, no correlation was seen between the gastric sleeve volume 3 months postoperatively and weight loss during this period. MDCT is a good method to measure gastric volume before and after LSG. Early post-operative weight loss (3 months) correlates well with the volume of the excised stomach but not with that of the gastric sleeve.
Bergman, Michael; Chetrit, Angela; Roth, Jesse; Dankner, Rachel
2015-05-01
We describe the relationship between dysglycemia and long-term mortality and elucidate the relationship between blood glucose levels during an oral glucose tolerance test (OGTT) and haemoglobin A1 (HbA1) and mortality. A cohort of 1410 individuals was followed for 33 years since 1980. Fasting and post-OGTT glucose parameters were used to categorize the cohort according to baseline glycemic status. The mortality rate increased from 43% in normoglycemic individuals to 53.3, 61.7, 72.9 and 88.0% in those with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), IFG/IGT and diabetes, respectively. The highest mortality rate, compared with the normoglycemic category, was observed in individuals with IFG/IGT and diabetes according to a Cox proportional hazard model (HR = 1.38, 95%CI 1.10-1.74 and HR = 2.14, 95%CI 1.70-2.70, respectively), followed by individuals with IGT and IFG, but this did not reach statistical significance. We speculate that the IFG group may represent a mixture of individuals en route from normal to the next two categories as well as another cohort whose glucose levels are stably set at the upper reaches of the normal distribution. Significant differences were found between 1 and 2 h glucose values (p < 0.001). Fasting, 60 and 120 min glucose values were positively associated with increasing HbA1 quintiles (p < 0.05). The mean HbA1 was significantly higher in those who died (p = 0.01). The highest mortality (58.8%) was observed in the upper HbA1 quintile that was also associated with the highest prevalence of the metabolic syndrome (17.2%). This study shows a continuous relationship between the severity of dysglycemia and long-term mortality and should promote the early recognition of prediabetes. The 1 h post-load glucose level was continuously associated with increasing HbA1 concentrations and may therefore serve as an early marker for abnormalities in glucose tolerance. An elevated 1 h post-load glucose level may potentially identify at-risk individuals well before the traditional 2 h glucose value. Copyright © 2014 John Wiley & Sons, Ltd.
The north-subducting Rheic Ocean during the Devonian: consequences for the Rhenohercynian ore sites
NASA Astrophysics Data System (ADS)
von Raumer, Jürgen F.; Nesbor, Heinz-Dieter; Stampfli, Gérard M.
2017-10-01
Base metal mining in the Rhenohercynian Zone has a long history. Middle-Upper Devonian to Lower Carboniferous sediment-hosted massive sulfide deposits (SHMS), volcanic-hosted massive sulfide deposits (VHMS) and Lahn-Dill-type iron, and base metal ores occur at several sites in the Rhenohercynian Zone that stretches from the South Portuguese Zone, through the Lizard area, the Rhenish Massif and the Harz Mountain to the Moravo-Silesian Zone of SW Bohemia. During Devonian to Early Carboniferous times, the Rhenohercynian Zone is seen as an evolving rift system developed on subsiding shelf areas of the Old Red continent. A reappraisal of the geotectonic setting of these ore deposits is proposed. The Middle-Upper Devonian to Early Carboniferous time period was characterized by detrital sedimentation, continental intraplate and subduction-related volcanism. The large shelf of the Devonian Old Red continent was the place of thermal subsidence with contemporaneous mobilization of rising thermal fluids along activated Early Devonian growth faults. Hydrothermal brines equilibrated with the basement and overlying Middle-Upper Devonian detrital deposits forming the SHMS deposits in the southern part of the Pyrite Belt, in the Rhenish Massif and in the Harz areas. Volcanic-hosted massive sulfide deposits (VHMS) formed in the more eastern localities of the Rhenohercynian domain. In contrast, since the Tournaisian period of ore formation, dominant pull-apart triggered magmatic emplacement of acidic rocks, and their metasomatic replacement in the apical zones of felsic domes and sediments in the northern part of the Iberian Pyrite belt, thus changing the general conditions of ore precipitation. This two-step evolution is thought to be controlled by syn- to post-tectonic phases in the Variscan framework, specifically by the transition of geotectonic setting dominated by crustal extension to a one characterized by the subduction of the supposed northern slab of the Rheic Ocean preceding the general Late Variscan crustal shortening and oroclinal bending.
Surgical Tooth Implants, Combat and Field.
1982-07-15
design. The serrated root portion is alumina ceramic. The upper two parts of the implant (post and core and crown) are conventional dental materials...ceramic. The upper two parts of the implant (post and core and crown) are conventional dental materials, usually gold. Roots are produced by grinding...I1 Clinical Examples of Baboon Dental Implants . . . .. . . . .. 12 Clinical Chemistry and Hematology Results in Baboons. . . . . . . 20
Field, Daniel J; Bercovici, Antoine; Berv, Jacob S; Dunn, Regan; Fastovsky, David E; Lyson, Tyler R; Vajda, Vivi; Gauthier, Jacques A
2018-06-04
The fossil record and recent molecular phylogenies support an extraordinary early-Cenozoic radiation of crown birds (Neornithes) after the Cretaceous-Paleogene (K-Pg) mass extinction [1-3]. However, questions remain regarding the mechanisms underlying the survival of the deepest lineages within crown birds across the K-Pg boundary, particularly since this global catastrophe eliminated even the closest stem-group relatives of Neornithes [4]. Here, ancestral state reconstructions of neornithine ecology reveal a strong bias toward taxa exhibiting predominantly non-arboreal lifestyles across the K-Pg, with multiple convergent transitions toward predominantly arboreal ecologies later in the Paleocene and Eocene. By contrast, ecomorphological inferences indicate predominantly arboreal lifestyles among enantiornithines, the most diverse and widespread Mesozoic avialans [5-7]. Global paleobotanical and palynological data show that the K-Pg Chicxulub impact triggered widespread destruction of forests [8, 9]. We suggest that ecological filtering due to the temporary loss of significant plant cover across the K-Pg boundary selected against any flying dinosaurs (Avialae [10]) committed to arboreal ecologies, resulting in a predominantly non-arboreal post-extinction neornithine avifauna composed of total-clade Palaeognathae, Galloanserae, and terrestrial total-clade Neoaves that rapidly diversified into the broad range of avian ecologies familiar today. The explanation proposed here provides a unifying hypothesis for the K-Pg-associated mass extinction of arboreal stem birds, as well as for the post-K-Pg radiation of arboreal crown birds. It also provides a baseline hypothesis to be further refined pending the discovery of additional neornithine fossils from the Latest Cretaceous and earliest Paleogene. Copyright © 2018 Elsevier Ltd. All rights reserved.
Dissolution of Permian salt and Mesozoic depositional trends, Powder River basin, Wyoming
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rasmussen, D.L.; Bean, D.W.
1983-08-01
Salt deposits in the Powder River basin of Wyoming occur in the Late Permian Ervay Member of the Goose Egg Formation which was deposited in a redbed-evaporite trend extending from the Williston basin of North Dakota to the Alliance basin of Nebraska and Wyoming. However, only remnants of the once extensive Ervay salt remain in the Powder River basin, with major salt dissolution events occurring during Late Jurassic and Early Cretaceous. Subsidence and deposition at the surface were contemporaneous with subsurface salt dissolution except in areas where uplift and erosion were occurring. Earliest dissolution of the Ervay salt occurred inmore » the Jurassic, during regional uplift and erosion of the overlying Triassic Chugwater Formation in the present Hartville uplift and southeastern Powder River basin areas. Thickness variations of the Canyon Springs and Stockade Beaver members of the early Late Jurassic Sundance Formation, which unconformably overlie the deeply eroded Chugwater Formation, may be related in part to dissolution of the Ervay salt. Extensive salt dissolution, synsubsidence, and syndeposition occurred throughout most of the Powder River basin during the latest Jurassic and Early Cretaceous. Many producing fields from the Mowry, Muddy, and Dakota formations exhibit either rapid stratigraphic changes syndepositional to salt collapse or fracture-enhanced reservoir quality due to postdepositional salt collapse. Major Muddy accumulations occurring in areas of local Ervay salt collapse include Kitty, Hilight, Fiddler Creek, and Clareton which have produced jointly over 172 million bbl of oil. The relationship of Ervay salt dissolution to Lower Cretaceous deposition can be exploited as an effective exploration tool.« less
PASSALI, D.; CARUSO, G.; ARIGLIANO, L.C.; PASSALI, F.M.; BELLUSSI, L.
2012-01-01
SUMMARY Obstructive sleep apnoea syndrome (OSAS) results from upper airway collapse during sleep. It represents an increasingly recognized pathology associated with many diseases. Herein, we describe a database for patients with OSAS. This has different goals: to facilitate good uniformity in clinical assessment, to allow the use of the application even by non-ENT specialists, to evaluate the results of medical and/or surgical treatments and to enable a statistical meta-analysis derived from the data collected in many OSAS medical centres. PMID:23093815
Depositional and deformational history of the Franciscan complex, northernmost California
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aalto, K.R.
1990-05-01
Pervasive extensional shear fractures and curvilinear arrays of clay and silt-filled veins in Franciscan Complex melanges and turbidites formed when Franciscan sediments were unlithified. Sandstone dikes both crosscut and follow fractures. Several scales of extensional faulting account for the juxtaposition of turbidites of different facies and/or with varying degrees of stratal disruption, the formation of sandstone lozenges and pinch-and-swell structures, and the formation of scaly foliation within the matrix of melange units. Within turbidites, the upper laminated portions of beds commonly contain abundant listric microfaults and the more massive lower portions of beds contain sediment-filled vein arrays. Veining and faultingmore » occurred concurrently and resulted in differential extension of upper verses lower portions of beds. The finer sediment in veins reflects both cataclasis and filtering in of clay and silt from vein walls. Most Franciscan rocks record an early pervasive, layer-parallel flattening strain, which may be related to the gravitational collapse of late Mesozoic Franciscan inner trench slope sediments that accompanied accretionary prism expansion resulting from underplating. However, some turbidites record noncoaxial extension that resulted from downslope creep of sediments. At Crescent City, sediment creep resulted in oversteepening of the Franciscan inner trench slope, which, in turn, may have triggered large-scale failure of slope materials resulting in the emplacement of the Crescent City olistostrome. The olistostrome crops out for 12 km along the coast, is up to 600 m thick, is in depositional contact with turbidites, and contains chiefly sandstone, greenstone, chert olistoliths up to 200 m across, and zones of slump-folded turbidites.« less
Aoshima, Ryota; Hiraoka, Rieko; Shimada, Nao; Kawata, Takefumi
2006-01-01
A Dd-STATa-null mutant, which is defective in expression of a Dictyostelium homologue of the metazoan STAT (signal transducers and activators of transcription) proteins, fails to culminate and this phenotype correlates with the loss of expression of various prestalk (pst) genes. An EST clone, SSK395, encodes a close homologue of the adducin amino-terminal head domain and harbors a putative actin-binding domain. We fused promoter fragments of the cognate gene, ahhA (adducin head homologue A), to a lacZ reporter and determined their expression pattern. The proximal promoter region is necessary for the expression of ahhA at an early (pre-aggregative) stage of development and this expression is Dd-STATa independent. The distal promoter region is necessary for expression at later stages of development in pstA cells, of the slug and in upper cup and pstAB cells during culmination. The distal region is partly Dd-STATa-dependent. The ahhA-null mutant develops almost normally until culmination, but it forms slanting culminants that tend to collapse on to the substratum. The mutant also occasionally forms fruiting bodies with swollen papillae and with constrictions in the prestalk region. The AhhA protein localizes to the stalk tube entrance and also to the upper cup cells and in cells at or near to the constricted region where an F-actin ring is localized. These findings suggest that Dd-STATa regulates culmination and may be necessary for straight downward elongation of the stalk, via the putative actin-binding protein AhhA.
Sethi, Amit; Davis, Sandra; McGuirk, Theresa; Patterson, Tara S.; Richards, Lorie G.
2012-01-01
Study Design Quasi-experimental design Introduction Although the effectiveness of constraint induced movement therapy (CIMT) in upper extremity (UE) rehabilitation post stroke is well known, the efficacy of CIMT to enhance the temporal structure of variability in upper extremity movement is not known. Purpose The purpose of this study was to investigate whether CIMT could enhance temporal structure of variability in upper extremity movement in individuals with chronic stroke. Methods Six participants with chronic stroke underwent CIMT for 4 hours/day for 2 weeks. Participants performed three trials of functional reach-to-grasp before and after CIMT. Temporal structure of variability was determined by calculating approximate entropy (ApEn) in shoulder, elbow and wrist flexion/extension joint angles. Results ApEn increased post CIMT, however, statistical significance was not achieved (p > 0.0167). Conclusion Future studies with larger sample size are warranted to investigate the effect of CIMT upon temporal structure of variability in UE movement. PMID:23084461
Acid rain research program. Annual progress report, September 1975--June 1976
DOE Office of Scientific and Technical Information (OSTI.GOV)
Evans, L.S.; Raynor, G.S.
1976-09-01
The aims of the research program are: (a) to observe the minimum threshold dose of simulated acid rain to produce visual and histological effects on plant foliage, (b) approach threshold limits of simulated sulfate acid rain that affect plant growth and reproduction, and (c) to measure chemical and meteorological parameters of incident rain. Acute leaf injury to several plant species resulted from exposure of foliage to simulated sulfate acid rain of pH level 2.3 to 2.9. Only slight injury occurred at 3.1. Scanning electron micrographs showed that injury to upper leaf surfaces occurred mostly at the base of trichomes (leafmore » hairs) and near stomata. An association of lesion development near vascular tissue was also noted. Histologically, lesions are characterized by an initial collapse of the epidermis with eventual lysis and collapse of more internal leaf tissues on the upper leaf surface of pinto beans which complemented detailed descriptions of visual lesion development after daily exposures to simulated rain. Initial experiments with gametophytes of Pteridium aquilinum show that reproduction of this fern species is very sensitive to solutions of pH 5.2 while vegetative development is not affected at pH levels of 2.2. Initial rain samples from the sequential sampler have been obtained. Initial portions of rain events exhibit a pH near 3.0 in some cases. More complete chemical analyses are anticipated.« less
Preliminary Seismological Report on the 6 August 2007 Crandall Canyon Mine Collapse in Utah
NASA Astrophysics Data System (ADS)
Pechmann, J. C.; Arabasz, W. J.; Pankow, K. L.; Burlacu, R.; McCarter, M. K.
2007-12-01
A large and tragic collapse occurred in the Crandall Canyon coal mine in east-central Utah on 6 Aug 2007, causing the loss of six miners and generating national attention. This collapse was accompanied by a local magnitude (ML) 3.9 seismic event having an origin time of 2:48 am MDT (8:48 UTC) and a location near the collapse. Two lines of evidence indicate that most of the seismic wave energy of this event was generated by the mine collapse rather than an earthquake: (1) the observation that all of the P-wave first motion directions are down and (2) the results of a moment tensor inversion by Ford et al. (2007; http://seismo.berkeley.edu/seismo/Homepage.html). The Crandall Canyon mine is in an area of Utah where there is abundant mining-induced seismicity, including events with both collapse and shear-slip sources. Prior to the 6 Aug collapse, and within a 3 km radius of it, there were 28 seismic events during 2007 that were large enough to be detected and located as part of the routine processing of University of Utah regional seismic network data: 8 in the 2.5-week period prior to the collapse (ML ≤ 1.9) and 15 during an earlier period of activity in late February and early March (ML ≤ 1.8). The 6 Aug collapse was followed by 37 locatable seismic events of ML ≤ 2.2 before the end of August. One of these "aftershocks" (ML 1.6) occurred in conjunction with the violent burst of coal from the mine walls on 17 Aug (UTC) that killed three rescuers. The aftershocks have an exponential frequency-magnitude distribution with a lower ratio between the frequencies of smaller- and larger-magnitude events (lower b-value) than for the prior events in the area. Aftershock rates generally decreased with time through August but there was a noteworthy 5.8-day hiatus in activity that began 37 hours after the collapse. The University of Utah deployed a 5-station temporary network near the mine beginning on 8 Aug. Data from these stations are being used to help develop travel-time corrections for these and other stations in order to improve the computed locations of seismic events that occurred in the area both before and after the 6 Aug collapse.
The Remarkable Deaths of 9-11 Solar Mass Stars
NASA Astrophysics Data System (ADS)
Woosley, S. E.; Heger, Alexander
2015-09-01
The post-helium-burning evolution of stars from 7 {M}⊙ to 11 {M}⊙ is complicated by the lingering effects of degeneracy and off-center ignition. Here, stars in this mass range are studied using a standard set of stellar physics. Two important aspects of the study are the direct coupling of a reaction network of roughly 220 nuclei to the structure calculation at all stages and the use of a subgrid model to describe the convective bounded flame that develops during neon and oxygen burning. Below 9.0 {M}⊙ degenerate oxygen-neon cores form that may become either white dwarfs or electron-capture supernovae. Above 10.3 {M}⊙ the evolution proceeds “normally” to iron-core collapse, without composition inversions or degenerate flashes. Emphasis here is upon the stars in between, which typically ignite oxygen burning off-center. After oxygen burns in a convectively bounded flame, silicon burning ignites in a degenerate flash that commences closer to the stellar center and with increasing violence for stars of larger mass. In some cases the silicon flash is so violent that it could lead to the early ejection of the hydrogen envelope. This might have interesting observable consequences. For example, the death of a 10.0 {M}⊙ star could produce two supernova-like displays, a faint low-energy event due to the silicon flash, and an unusually bright supernova many months later as the low-energy ejecta from core collapse collides with the previously ejected envelope. The potential relation to the Crab supernova is discussed.
Bárðarbunga volcano - post-eruption trends following the Holuhraun eruption in 2014-2015
NASA Astrophysics Data System (ADS)
Jónsdóttir, Kristín; Hooper, Andrew; Jónasson, Kristján; Vogfjörð, Kristín; Tumi Gudmundsson, Magnús; Hjorleifsdóttir, Vala; Rodríguez-Cardozo, Felix R.; Sigmundsson, Freysteinn; Ófeigsson, Benedikt G.; Parks, Michelle M.; Roberts, Matthew; Gudmundsson, Gunnar B.; Hognadóttir, Thordis; Pfeffer, Melissa A.; Geirsson, Halldór; Barsotti, Sara; Oddsson, Bjorn
2017-04-01
The Bárdarbunga volcano in central Iceland experienced a major unrest, lateral dyking, and eruption in August 2014-February 2015. The eruption was accompanied by caldera collapse, a truly rare event that has not been monitored in such detail before, providing a unique opportunity for better understanding the volcanic structure and processes. The collapse was extensive as the 8x11 km caldera gradually subsided and a subsidence bowl up to 65 m deep was formed, while about 1.8 km3 of magma drained laterally along a subterranean path, forming a flood basalt 47 km northeast of the volcano. The collapse was accompanied by high rates of seismicity and 80 earthquakes between M5-M5.8 were recorded. Using various geophysical and geochemical data, together with modelling, the magma reservoir has been estimated to reside at about 8-12 km depth beneath the caldera and recent findings show that the subsidence was driven by a feedback between the pressure of the piston-like block overlying the reservoir, and the 47 km long magma outflow path. The collapse and magma outflow gradually declined until the eruption ended on the 27th February 2015. After the end of the eruption, GPS deformation data show horizontal movements that seem to be in line with an inflation signal centered at the caldera, but the pattern is more complicated than during the co-eruptive period. The seismicity continued to decline, both in the far end of the dyke as well as within the caldera. However, in September 2015 seismicity within the caldera started to increase again. Interestingly, this increase was identified in terms of increased earthquake magnitudes while earthquake rate remained relatively constant. This resulted in a volcanic earthquake catalog with the highest seismic moment release rate ever recorded in Iceland during times of volcanic quiescence. Here we present a seismic waveform correlation analysis which reveals a dramatic change occurring between February and May 2015, where the earthquakes' first motion polarity reverses sign. This time coincides with the ending of the caldera collapse and the eruption. We investigate relative locations of the earthquakes as well as moment tensor solutions and compare results of the post-eruption period to the period during caldera subsidence and eruptive activity. In addition, we present analysis of post-eruption trends of the deformation data as well as seismicity trends. Preliminary results suggest that caldera fault movements where reversed soon after the eruption ended in spring 2015 when we also observe outwards movement of GPS stations around the caldera, indicating re-inflation long before any seismicity increase was detected. These data and their interpretation are vital to understanding the current status of the volcano and, eventually, to perform a more accurate and reliable hazard assessment.
Continuous monitoring of kidney transplant perfusion with near-infrared spectroscopy.
Malakasioti, Georgia; Marks, Stephen D; Watson, Tom; Williams, Fariba; Taylor-Allkins, Mariesa; Mamode, Nizam; Morgan, Justin; Hayes, Wesley N
2018-05-11
Current reliance on clinical, laboratory and Doppler ultrasound (DUS) parameters for monitoring kidney transplant perfusion in the immediate post-operative period in children risks late recognition of allograft hypoperfusion and vascular complications. Near-infrared spectroscopy (NIRS) is a real-time, non-invasive technique for monitoring tissue oxygenation percutaneously. NIRS monitoring of kidney transplant perfusion has not previously been validated to the gold standard of DUS. We examined whether NIRS tissue oxygenation indices can reliably assess blood flow in established paediatric kidney transplants. Paediatric kidney transplant recipients ages 1-18 years with stable allograft function were eligible. Participants underwent routine DUS assessment of kidney transplant perfusion, including resistive index (RI) and peak systolic velocity at the upper and lower poles. NIRS data [tissue oxygenation index (TOI%)] were recorded for a minimum of 2 min with NIRS sensors placed on the skin over upper and lower allograft poles. Twenty-nine subjects with a median age of 13.3 (range 4.8-17.8) years and a median transplant vintage of 26.5 months participated. Thirteen (45%) were female and 20 (69%) were living donor kidney recipients. NIRS monitoring was well tolerated by all, with 96-100% valid measurements. Significant negative correlations were observed between NIRS TOI% and DUS RI at both the upper and lower poles (r = -0.4 and -0.6, P = 0.04 and 0.001, respectively). Systolic blood pressure but not estimated glomerular filtration rate also correlated with NIRS TOI% (P = 0.01). NIRS indices correlate well with DUS perfusion and haemodynamic parameters in established paediatric kidney transplant recipients. Further studies are warranted to extend NIRS use for continuous real-time monitoring of early post-transplant perfusion status.
Schmitz, Kathryn H; DiSipio, Tracey; Gordon, Louisa G; Hayes, Sandra C
2015-06-01
The purpose of this work was to evaluate the patient-borne financial cost of common, adverse breast cancer treatment-associated effects, comparing cost across women with or without these side effects. Two hundred eighty-seven Australian women diagnosed with early-stage breast cancer were prospectively followed starting at 6 months post-surgery for 12 months, with three monthly assessments of detailed treatment-related side effects and their direct and indirect patient costs attributable to breast cancer. Bootstrapping statistics were used to analyze cost data, and adjusted logistic regression was used to evaluate the association between costs and adverse events from breast cancer. Costs were inflated and converted from 2002 Australian to 2014 US dollars. More than 90 % of women experienced at least one adverse effect (i.e., post-surgical issue, reaction to radiotherapy, upper-body symptoms or reduced function, lymphedema, fatigue, or weight gain). On average, women paid $5,636 (95 % confidence interval (CI), $4,694, $6,577) in total costs. Women with any one of the following symptoms (fatigue, reduced upper-body function, upper-body symptoms) or women who report ≥4 adverse treatment-related effects, have 1.5 to nearly 4 times the odds of having higher healthcare costs than women who do not report these complaints (p < 0.05). Women face substantial economic burden due to a range of treatment-related health problems, which may persist beyond the treatment period. Improving breast cancer care by incorporating prospective surveillance of treatment-related side effects and strategies for prevention and treatment of concerns (e.g., exercise) has real potential for reducing patient-borne costs.
The Development of Upper Limb Movements: From Fetal to Post-Natal Life
Zoia, Stefania; Blason, Laura; D’Ottavio, Giuseppina; Biancotto, Marina; Bulgheroni, Maria; Castiello, Umberto
2013-01-01
Background The aim of this longitudinal study was to investigate how the kinematic organization of upper limb movements changes from fetal to post-natal life. By means of off-line kinematical techniques we compared the kinematics of hand-to-mouth and hand-to-eye movements, in the same individuals, during prenatal life and early postnatal life, as well as the kinematics of hand-to-mouth and reaching-toward-object movements in the later age periods. Methodology/Principal Findings Movements recorded at the 14th, 18th and 22nd week of gestation were compared with similar movements recorded in an ecological context at 1, 2, 3, 4, 8, and 12 months after birth. The results indicate a similar kinematic organization depending on movement type (i.e., eye, mouth) for the infants at one month and for the fetuses at 22 weeks of gestation. At two and three months such differential motor planning depending on target is lost and no statistical differences emerge. Hand to eye movements were no longer observed after the fourth month of life, therefore we compared kinematics for hand to mouth with hand to object movements. Results of these analyses revealed differences in the performance of hand to mouth and reaching to object movements in the length of the deceleration phase of the movement, depending on target. Conclusion/Significance Data are discussed in terms of how the passage from intrauterine to extra-uterine environments modifies motor planning. These results provide novel evidence of how different types of upper extremity movements, those directed towards one’s own face and those directed to external objects, develop. PMID:24324642
Eiríksdóttir, Védís Helga; Valdimarsdóttir, Unnur Anna; Ásgeirsdóttir, Tinna Laufey; Hauksdóttir, Arna; Lund, Sigrún Helga; Bjarnadóttir, Ragnheiður Ingibjörg; Cnattingius, Sven; Zoëga, Helga
2015-01-01
Data on the potential influence of macroeconomic recessions on maternal diseases during pregnancy are scarce. We aimed to assess potential change in prevalence of pregnancy-induced hypertensive disorders (preeclampsia and gestational hypertension) during the first years of the major national economic recession in Iceland, which started abruptly in October 2008. Women whose pregnancies resulted in live singleton births in Iceland in 2005-2012 constituted the study population (N = 35,211). Data on pregnancy-induced hypertensive disorders were obtained from the Icelandic Medical Birth Register and use of antihypertensive drugs during pregnancy, including β-blockers and calcium channel blockers, from the Icelandic Medicines Register. With the pre-collapse period as reference, we used logistic regression analysis to assess change in pregnancy-induced hypertensive disorders and use of antihypertensives during the first four years after the economic collapse, adjusting for demographic and pregnancy characteristics, taking aggregate economic indicators into account. Compared with the pre-collapse period, we observed an increased prevalence of gestational hypertension in the first year following the economic collapse (2.4% vs. 3.9%; adjusted odds ratio [aOR] 1.47; 95 percent confidence interval [95%CI] 1.13-1.91) but not in the subsequent years. The association disappeared completely when we adjusted for aggregate unemployment rate (aOR 1.04; 95% CI 0.74-1.47). Similarly, there was an increase in prescription fills of β-blockers in the first year following the collapse (1.9% vs.3.1%; aOR 1.43; 95% CI 1.07-1.90), which disappeared after adjusting for aggregate unemployment rate (aOR 1.05; 95% CI 0.72-1.54). No changes were observed for preeclampsia or use of calcium channel blockers between the pre- and post-collapse periods. Our data suggest a transient increased risk of gestational hypertension and use of β-blockers among pregnant women in Iceland in the first and most severe year of the national economic recession.
Computed tomography-guided tissue engineering of upper airway cartilage.
Brown, Bryan N; Siebenlist, Nicholas J; Cheetham, Jonathan; Ducharme, Norm G; Rawlinson, Jeremy J; Bonassar, Lawrence J
2014-06-01
Normal laryngeal function has a large impact on quality of life, and dysfunction can be life threatening. In general, airway obstructions arise from a reduction in neuromuscular function or a decrease in mechanical stiffness of the structures of the upper airway. These reductions decrease the ability of the airway to resist inspiratory or expiratory pressures, causing laryngeal collapse. We propose to restore airway patency through methods that replace damaged tissue and improve the stiffness of airway structures. A number of recent studies have utilized image-guided approaches to create cell-seeded constructs that reproduce the shape and size of the tissue of interest with high geometric fidelity. The objective of the present study was to establish a tissue engineering approach to the creation of viable constructs that approximate the shape and size of equine airway structures, in particular the epiglottis. Computed tomography images were used to create three-dimensional computer models of the cartilaginous structures of the larynx. Anatomically shaped injection molds were created from the three-dimensional models and were seeded with bovine auricular chondrocytes that were suspended within alginate before static culture. Constructs were then cultured for approximately 4 weeks post-seeding and evaluated for biochemical content, biomechanical properties, and histologic architecture. Results showed that the three-dimensional molded constructs had the approximate size and shape of the equine epiglottis and that it is possible to seed such constructs while maintaining 75%+ cell viability. Extracellular matrix content was observed to increase with time in culture and was accompanied by an increase in the mechanical stiffness of the construct. If successful, such an approach may represent a significant improvement on the currently available treatments for damaged airway cartilage and may provide clinical options for replacement of damaged tissue during treatment of obstructive airway disease.
NASA Astrophysics Data System (ADS)
Pritchard, Chad J.; Larson, Peter B.
2012-08-01
An array of samples from the eastern Upper Basin Member of the Plateau Rhyolite (EUBM) in the Yellowstone Plateau, Wyoming, were collected and analyzed to evaluate styles of deposition, geochemical variation, and plausible sources for low δ18O rhyolites. Similar depositional styles and geochemistry suggest that the Tuff of Sulphur Creek and Tuff of Uncle Tom's Trail were both deposited from pyroclastic density currents and are most likely part of the same unit. The middle unit of the EUBM, the Canyon flow, may be composed of multiple flows based on a wide range of Pb isotopic ratios (e.g., 206Pb/204Pb ranges from 17.54 to 17.86). The youngest EUBM, the Dunraven Road flow, appears to be a ring fracture dome and contains isotopic ratios and sparse phenocrysts that are similar to extra-caldera rhyolites of the younger Roaring Mountain Member. Petrologic textures, more radiogenic 87Sr/86Sr in plagioclase phenocrysts (0.7134-0.7185) than groundmass and whole-rock ratios (0.7099-0.7161), and δ18O depletions on the order of 5‰ found in the Tuff of Sulphur Creek and Canyon flow indicate at least a two-stage petrogenesis involving an initial source rock formed by assimilation and fractional crystallization processes, which cooled and was hydrothermally altered. The source rock was then lowered to melting depth by caldera collapse and remelted and erupted. The presence of a low δ18O extra-caldera rhyolite indicates that country rock may have been hydrothermally altered at depth and then assimilated to form the Dunraven Road flow.
Popenoe, Peter; Kohout, F.A.; Manheim, F.T.; ,
1984-01-01
High-resolution seismic-reflection profiles show that the shelf off northern Florida is underlain by solution deformed limestone of Oligocene, Eocene, Paleocene and late Cretaceous age. Dissolution and collapse features are widely scattered. They are expressed in three general forms: as sinkholes that presently breach the sea floor, such as Red Snapper Sink and the Crescent Beach submarine spring; as sinkholes that have breached the seafloor in the past but are now filled with shelf sands; and as dissolution collapse structures that originate deep within the section and have caused buckling and folding of overlying Eocene, Oligocene, and to a lesser extent, Neogene strata. Although deformation caused by solution and collapse can be shown to be a continuous process, the major episode of karstification occurred in the late Oligocene and early Miocene when the shelf was exposed to subaerial conditions.
Rosseger, Agnieszka; Hanuszkiewicz, Justyna; Woźniewski, Marek
2014-01-01
Introduction Secondary lymphedema affects approximately 40% of women treated for breast cancer and is recognized as a major problem associated with the therapy of malignant tumors. Consequently, new therapeutic methods are constantly being sought to effectively eliminate the condition. One of the new forms of edema management, especially in the initial stages of edematous development, is Kinesiology Taping (KT). Aim of the study The aim of the study was to assess the effects of KT applications on the extent of lymphedema of the upper extremity in women post cancer treatment. Material and methods The study group consisted of 28 women after axillary lymphadenectomy due to breast cancer. All the patients were diagnosed with grade I secondary lymphedema. Kinesiology Taping was applied to a total of 14 randomly selected women. The remaining 14 patients constituted a control group. The extent of lymphedema was measured using a centimeter tape and Limb Volumes Professional 5.0 software. Results A significant reduction in the extent of lymphedema (p = 0.0009) was achieved in the KT group between baseline and post-treatment assessments. No such reduction, however, was found in the control group (p = 0.36). Conclusions Kinesiology Taping applications are an effective method of early-stage edema management. Kinesiology Taping may be a safe new therapeutic option in patients who are contraindicated for the use of other methods. PMID:26327858
[Laparoscopic Proximal Gastrectomy as a Surgical Treatment for Upper Third Early Gastric Cancer].
Park, Do Joong; Park, Young Suk; Ahn, Sang Hoon; Kim, Hyung Ho
2017-09-25
Recently, the incidence of upper third gastric cancer has increased, and with it the number of endoscopic submucosal dissection (ESD) procedures performed has been increasing. However, if ESD is not indicated or non-curable, surgical treatment may be necessary. In the case of lower third gastric cancer, it is possible to preserve the upper part of the stomach; however, in the case of upper third gastric cancer, total gastrectomy is still the standard treatment option, regardless of the stage. This is due to the complications associated with upper third gastric cancer, such as gastroesophageal reflux after proximal gastrectomy rather than oncologic problems. Recently, the introduction of the double tract reconstruction method after proximal gastrectomy has become one of the surgical treatment methods for upper third early gastric cancer. However, since there has not been a prospective comparative study evaluating its efficacy, the ongoing multicenter prospective randomized controlled trial (KLASS-05) comparing laparoscopic proximal gastrectomy with double tract reconstruction and laparoscopic total gastrectomy is expected to be important for determining the future of treatment of upper third early gastric cancer.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Foxwall, W.
2000-07-24
Ground surface subsidence resulting from the March 1992 JUNCTION underground nuclear test at the Nevada Test Site (NTS) imaged by satellite synthetic aperture radar interferometry (InSAR) wholly occurred during a period of several months after the shot (Vincent et al., 1999) and after the main cavity collapse event. A significant portion of the subsidence associated with the small (less than 20 kt) GALENA and DIVIDER tests probably also occurred after the shots, although the deformation detected in these cases contains additional contributions from coseismic processes, since the radar scenes used to construct the deformation interferogram bracketed these two later events,more » The dimensions of the seas of subsidence resulting from all three events are too large to be solely accounted for by processes confined to the damage zone in the vicinity of the shot point or the collapse chimney. Rather, the subsidence closely corresponds to the span dimensions predicted by Patton's (1990) empirical relationship between spall radius and yield. This suggests that gravitational settlement of damaged rock within the spall zone is an important source of post-shot subsidence, in addition to settlement of the rubble within the collapse chimney. These observations illustrate the potential power of InSAR as a tool for Comprehensive Nuclear-Test-Ban Treaty (CTBT) monitoring and on-site inspection in that the relatively broad ({approx} 100 m to 1 km) subsidence signatures resulting from small shots detonated at normal depths of burial (or even significantly overburied) are readily detectable within large geographical areas (100 km x 100 km) under favorable observing conditions. Furthermore, the present results demonstrate the flexibility of the technique in that the two routinely gathered satellite radar images used to construct the interferogram need not necessarily capture the event itself, but can cover a time period up to several months following the shot.« less
Whither the Heavy Forces in the Post-Containment World
1990-04-20
Japan (50,500), Philippines (17,300) and Panama (10,700).1 The European forces will be reduced by the Conventional Forces in Europe (CFE) treaty,2 by a... tardy in responding. This would be particularly damaging if the integrity of some major oil fields were at stake or if the collapse of a friendly
Business Schools Flourish in Post-Communist Eastern Europe.
ERIC Educational Resources Information Center
Bollag, Burton
1997-01-01
About 1,000 new business and management schools have opened in Eastern Europe and former Soviet republics since the collapse of Communist rule. All present appealing fronts, but many are insubstantial. Some multinational companies are using the new institutions to train local managers. At many, English is the language of instruction. An…
Sign(al)s: Living and Learning as Semiotic Engagement
ERIC Educational Resources Information Center
Stables, Andrew
2006-01-01
Cartesian mind-body dualism, while often explicitly denied, has left a legacy of conceptions that remain highly influential in education. I argue that trends in both analytic and continental philosophy of language point towards a post-Cartesian settlement in which the distinction between "signs" and "signals" is collapsed, and which thus construes…
NASA Astrophysics Data System (ADS)
Massey, M. A.; Moecher, D. P.
2006-12-01
One widely cited model for Appalachian orogenesis in New England invokes the tripartite Alpine sequence of nappe folding/thrusting, back-folding, and doming to explain regional and outcrop-scale structural relationships. Recent work suggests lateral extrusion driven by oblique convergence as an important mechanism responsible for structures, fabrics, and mineral assemblages in the Bronson Hill terrane (BHT) of Connecticut and Massachusetts. Just as the Alpine model has evolved to incorporate elements of lateral extrusion, and syn- to post-orogenic collapse, we propose similar revisions for southern New England. Detailed mapping and structural analysis of the W- to WNW-dipping BHT in south-central MA reveals: (1) a sub-vertical, transpressional dextral thrust high strain zone (Bonemill/Conant Brook shear zone) bounding the eastern margin of the Monson granitic gneiss dome (MG) with two modes of Sil+Qtz+Fs lineations plunging WNW and SSW; (2) a moderate to steeply-dipping sinistral high strain zone bounding the western margin of the MG with WNW- and SSW-plunging Ms+Qtz+Grt lineations; (3) an apparently random arrangement of gneiss, s and s-l tectonites, protomylonites, and mylonites composing the body of the MG, also containing WNW and SSW Qtz+Fs lineations. Extrapolation to a regional scale from central CT to northern MA indicates: (1) a gradual increase in s-l and l-s tectonites to the north from predominantly s-tectonites in central CT; (2) transition of lineation plunge from NW in central CT to bimodal WNW and SSW distribution to the north; (3) amphibolite facies metamorphism was pre- to synkinematic with respect to deformation. We propose that these observations may be accounted for by transpression and extrusion, rather than discreet phases of deformation invoked by the traditional three-stage model. Synchronous operation of high strain zones bounding the MG accommodated northward orogen-parallel extrusion in addition to a component of orogen-normal shortening and sub-vertical extrusion, thus constituting bulk heterogeneous flow. Existing geochronology/thermochronology constrains deformation to the late Paleozoic Alleghanian orogeny. The consistency in timing and similarity in style with deformation associated with the Pelham dome demonstrate the significance of orogen-parallel flow in the BHT. We go further by presenting a working late Paleozoic tectonic model incorporating data from this study with existing contributions from other workers in southern New England. This model involves oblique convergence and underthrusting of Avalon in the late Mississippian/early Pennsylvanian continuing into and throughout most of the Permian. Synorogenic compressional and extensional structures from upper amphibolite to greenschist facies are explained by progressive deformation, including extrusion, orogenic collapse, and wedging, throughout an evolving metamorphic gradient.
STOCHASTICITY AND EFFICIENCY IN SIMPLIFIED MODELS OF CORE-COLLAPSE SUPERNOVA EXPLOSIONS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cardall, Christian Y.; Budiardja, Reuben D., E-mail: cardallcy@ornl.gov, E-mail: reubendb@utk.edu
2015-11-01
We present an initial report on 160 simulations of a highly simplified model of the post-bounce core-collapse supernova environment in three spatial dimensions (3D). We set different values of a parameter characterizing the impact of nuclear dissociation at the stalled shock in order to regulate the post-shock fluid velocity, thereby determining the relative importance of convection and the stationary accretion shock instability (SASI). While our convection-dominated runs comport with the paradigmatic notion of a “critical neutrino luminosity” for explosion at a given mass accretion rate (albeit with a nontrivial spread in explosion times just above threshold), the outcomes of ourmore » SASI-dominated runs are much more stochastic: a sharp threshold critical luminosity is “smeared out” into a rising probability of explosion over a ∼20% range of luminosity. We also find that the SASI-dominated models are able to explode with 3–4 times less efficient neutrino heating, indicating that progenitor properties, and fluid and neutrino microphysics, conducive to the SASI would make the neutrino-driven explosion mechanism more robust.« less
Evidences of Silurian dextral transpression in the Scandinavian Caledonides
NASA Astrophysics Data System (ADS)
Torgersen, Espen; Viola, Giulio
2017-04-01
The Scandinavian Caledonides are classically interpreted as a fold and thrust belt resulting from the collision between Laurentia and Baltica during the Silurian, which involved the up-to-400 km ESE-wards translation of nappes onto the Baltoscandian platform. It has been suggested that the Caledonian fold and thrust belt formed through several distinct orogenic episodes, from early shortening in the Late Ordovician to orogenic collapse in the Devonian. The classic Caledonian, orogen-perpendicular ESE-ward nappe transport is constrained by abundant and consistently oriented stretching lineations across the entire orogen and unambiguous kinematic indicators. However, there is also a large number of NW-SE-trending and roughly orogen-parallel lineations, particularly in the upper ophiolite- and eclogite-bearing nappes, which are more challenging to interpret with the traditional orogeny evolution model. The analysis of the areal extent, spatial distribution and geometrical relationships of the Caledonian nappes in southern and central Norway, however, offers new insights and allows for new constraints on the bulk kinematic framework of the shortening history of the belt. Here we present new, first-order geological observations that demonstrate a two-fold compressional history and associated strain partitioning during Caledonian convergence. More specifically, we propose that Late Ordovician NNW-SSE shortening caused early compression, followed by WNW-ESE Early Silurian shortening, which resulted in strain partitioning along the planar fabrics and discontinuities from the earlier event. In detail, orogen-parallel dextral wrench tectonics caused significant lateral displacement along at least three, orogen-scale NE-SW striking corridors, wherein the nappes appear to be consistently displaced in a dextral fashion. We propose that the Møre-Trøndelag Fault Complex, which accommodated significant sinistral displacements during the later Devonian orogenic collapse, localized on one of these early dextral shear corridor. This is expressed by the asymptotic dragging of the nappes along it and also the significant morphological asymmetry of the central Norwegian coast line, which is not compatible with sinistral shearing. Along a southern corridor, which extends from the Hardangerfjord to the east of Folldal, the Caledonian foliation is asymptotically bent into the ENE-WSW orientation of the shear corridor, also consistent with an overall dextral kinematics. This is also confirmed by the gradual reorientation and increased strain toward these shear corridors of Ordovician to Silurian intrusive bodies, indicating that the dextral displacement is of Silurian age. Similar dextral displacements along NE-SW faults have previously been interpreted from potential field data offshore southern Norway. Large-scale dextral transpression in the Scandinavian Caledonides readily accounts for numerous geological features that are not as easily reconciled with the more classical model of only ESE-ward translation and/or sinistral transpression.
NASA Astrophysics Data System (ADS)
Gaullier, Virginie; Chanier, Frank; Vendeville, Bruno; Maillard, Agnès; Thinon, Isabelle; Graveleau, Fabien; Lofi, Johanna; Sage, Françoise
2016-04-01
The Eastern Sardinian passive continental margin formed during the opening of the Tyrrhenian Sea, which is a back-arc basin created by continental rifting and oceanic spreading related to the eastward migrating Apennine subduction system (middle Miocene to Pliocene). Up to now, rifting in this key area was considered to be pro parte coeval with the Messinian Salinity Crisis (MSC, 5.96-5.32 Ma). We use the MSC seismic markers and the deformation of viscous salt and its brittle overburden as proxies to better delineate the timing of rifting and post-rift reactivation, and especially to quantify vertical and horizontal movements. On this young, highly-segmented margin, the Messinian Erosion Surface and the Upper and Mobile Units are systematically associated, respectively, to basement highs and deeper basins, showing that a rifted deep-sea domain already existed by Messinian times, therefore a major pre-MSC rifting episode occurred across the entire domain. Data show that there are no signs of Messinian syn-rift sediments, hence no evidence for rifting after Late Tortonian times. Moreover, because salt tectonics creates fan-shaped geometries in sediments, syn-rift deposits have to be carefully re-examined to distinguish the effects of crustal tectonics (rifting) and salt tectonics. We also precise that rifting is clearly diachronous from the upper margin (East-Sardinia Basin) to the lower margin (Cornaglia Terrace) with two unconformities, attributed respectively to the necking and to the lithospheric breakup unconformities. The onshore part of the upper margin has been recently investigated in order to characterize the large crustal faults affecting the Mesozoic series (geometry, kinematics and chronology) and to decipher the role of the structural inheritance and of the early rifting. Seaward, we also try to constrain the architecture and timing of the continent-ocean transition, between the hyper-extended continental crust and the first oceanic crust. Widespread post-breakup deformation also occurred during the Pliocene. Some Pliocene vertical movements have been evidenced by discovering localized gravity gliding of the salt and its Late Messinian (UU) and Early Pliocene overburden. To the South, crustal-scale southward tilting triggered along-strike gravity gliding of salt and cover recorded by upslope extension and downslope shortening. To the North, East of the Baronie Ridge, there was some post-salt crustal activity along a narrow N-S basement trough, bounded by crustal faults. The salt geometry would suggest that nothing happened after Messinian times, but some structural features (confirmed by analogue modelling) show that basement fault slip was accommodated by lateral salt flow, which thinned upslope and thickened downslope, while the overlying sediments remained sub-horizontal. Along the inner domain of Eastern Sardinian margin, the post-rift deformation style greatly varies. Compressional structures (reverse faults and folds) are observed both onshore and offshore while post-rift extensional structures are mainly identified offshore. Such late deformation could be attributed to mechanisms acting alone or combined, such as : i. the reactivation of the margin, as already described for the Ligurian, Algerian or South-Balearic margins due to the Eurasian-African convergence ; 2. the Zanclean reflooding and the resulting water overload on the elastic lithosphere ; 3. an episodic mantle upwelling.
Postural Effects on Pharyngeal Protective Reflex Mechanisms
Malhotra, Atul; Trinder, John; Fogel, Robert; Stanchina, Michael; Patel, Sanjay R.; Schory, Karen; Kleverlaan, Darci; White, David P.
2012-01-01
Study Objectives Pharyngeal muscle dilators are important in obstructive sleep apnea pathogenesis because the failure of protective reflexes involving these muscles yields pharyngeal collapse. Conflicting results exist in the literature regarding the responsiveness of these muscles during stable non-rapid eye movement sleep. However, variations in posture in previous studies may have influenced these findings. We hypothesized that tongue protruder muscles are maximally responsive to negative pressure pulses during supine sleep, when posterior tongue displacement yields pharyngeal occlusion. Design We studied all subjects in the supine and lateral postures during wakefulness and stable non-rapid eye movement sleep by measuring genioglossus and tensor palatini electromyograms during basal breathing and following negative pressure pulses. Setting Upper-airway physiology laboratory of Sleep Medicine Division, Brigham and Women’s Hospital. Subjects/Participants 17 normal subjects. Measurements and Results We observed an increase in genioglossal responsiveness to negative pressure pulses in sleep as compared to wakefulness in supine subjects (3.9 percentage of maximum [%max] ± 1.1 vs 4.4 %max ± 1.0) but a decrease in the lateral decubitus position (4.1 %max ± 1.0 vs 1.5 %max ± 0.4), the interaction effect being significant. Despite this augmented reflex, collapsibility, as measured during negative pressure pulses, increased more while subjects were in the supine position as compared with the lateral decubitus position. While the interaction between wake-sleep state and position was also significant for the tensor palatini, the effect was weaker than for genioglossus, although, for tensor palatini, baseline activity was markedly reduced during non-rapid eye movement sleep as compared with wakefulness. Conclusions We conclude that body posture does have an important impact on genioglossal responsiveness to negative pressure pulses during non-rapid eye movement sleep. We speculate that this mechanism works to prevent pharyngeal occlusion when the upper airway is most vulnerable to collapse eg, during supine sleep. PMID:15532204
Ground deformation at Merapi Volcano, Java, Indonesia: distance changes, June 1988-October 1995
Young, K.D.; Voight, B.; ,; ,; ,; Casadevall, T.J.
2000-01-01
Edifice deformations are reported here for the period 1988–1995 at Merapi volcano, one of the most active and dangerous volcanoes in Indonesia. The study period includes a major resumption in lava effusion in January 1992 and a major dome collapse in November 1994. The data comprise electronic distance measurements (EDM) on a summit trilateration network, slope distance changes measured to the upper flanks, and other data collected from 1988 to 1995. A major consequence of this study is the documentation of a significant 4-year period of deformation precursory to the 1992 eruption. Cross-crater strain rates accelerated from less than 3×10−6/day between 1988 and 1990 to more than 11×10−6/day just prior to the January 1992 activity, representing a general, asymmetric extension of the summit during high-level conduit pressurization. After the vent opened and effusion of lava resumed, strain occurred at a much-reduced rate of less than 2×10−6/day. EDM measurements between lower flank benchmarks and the upper edifice indicate displacements as great as 1 m per year over the four years before the 1992 eruption. The Gendol breach, a pronounced depression formed by the juxtaposition of old lava coulées on the southeast flank, functioned as a major displacement discontinuity. Since 1993, movements have generally not exceeded the 95% confidence limits of the summit network. Exceptions to this include 12 cm outward movement for the northwest crater rim in 1992–1993, probably from loading by newly erupted dome lava, and movements as much as 7 cm on the south flank between November 1994 and September 1995. No short-term precursors were noted before the November 1994 lava dome collapse, but long-term adjustments of crater geometry accompanied lava dome growth in 1994. Short-term 2-cm deflation of the edifice occurred following the November 1994 dome collapse.
Community dynamics of nematodes after Larsen ice-shelf collapse in the eastern Antarctic Peninsula.
Hauquier, Freija; Ballesteros-Redondo, Laura; Gutt, Julian; Vanreusel, Ann
2016-01-01
Free-living marine nematode communities of the Larsen B embayment at the eastern Antarctic Peninsula were investigated to provide insights on their response and colonization rate after large-scale ice-shelf collapse. This study compares published data on the post-collapse situation from 2007 with new material from 2011, focusing on two locations in the embayment that showed highly divergent communities in 2007 and that are characterized by a difference in timing of ice-shelf breakup. Data from 2007 exposed a more diverse community at outer station B.South, dominated by the genus Microlaimus. On the contrary, station B.West in the inner part of Larsen B was poor in both numbers of individuals and genera, with dominance of a single Halomonhystera species. Re-assessment of the situation in 2011 showed that communities at both stations diverged even more, due to a drastic increase in Halomonhystera at B.West compared to relatively little change at B.South. On a broader geographical scale, it seems that B.South gradually starts resembling other Antarctic shelf communities, although the absence of the genus Sabatieria and the high abundance of Microlaimus still set it apart nine years after the main Larsen B collapse. In contrast, thriving of Halomonhystera at B.West further separates its community from other Antarctic shelf areas.
NASA Astrophysics Data System (ADS)
Capra, L.
2010-12-01
Climate changes have been considered to be a triggering mechanism for large magmatic eruptions. However they can also trigger volcanic collapses, phenomena that cause the destruction of the entire sector of a volcano, including its summit. During the past 30 ka, major volcanic collapses occurred just after main glacial peaks that ended with a rapid deglaciation. Glacial debuttressing, load discharge and fluid circulation coupled with the post-glacial increase of humidity and heavy rains can activate the failure of unstable edifices. Looking at the synchronicity of the maximum glaciations during the late Pleistocene and Holocene in the northern and southern hemispheres it is evident that several volcanic collapses are absent during a glacial climax, but start immediately after it during a period of rapid retreat. Several examples can be detected around the world and Mexico is not an exception. The 28 ka Nevado de Toluca volcanic collapse occurred during an intraglacial stage, under humid conditions as evidenced by paleoclimatic studies on lacustrine sediments of the area. The debris avalanche deposit associated to this event clearly shows evidence of a large amount of water into the mass previous to the failure that enhanced its mobility. It also contains peculiar, plastically deformed, m-sized fragment of lacustrine sediments eroded from glacial berms. The 17 ka BP collapse of the Colima Volcano corresponds to the initial stage of glacial retreat in Mexico after the Last Glacial Maximum (22-17.5ka). Also in this case the depositional sequence reflects high humidity conditions with voluminous debris flow containing a large amount logs left by pine trees. The occurrence of cohesive debris flows originating from the failure of a volcanic edifice can also reflect the climatic conditions, indicating important hydrothermal alteration and fluid circulation from ice-melting at an ice-capped volcano, as observed for example at the Pico de Orizaba volcano for the Tetelzingo lahar, which collapse occurred after the Terminal Glacial (15-11 ka). Furthermore, significant global warming can be responsible for the collapse of ice-capped unstable volcanoes, an unpredictable hazard that in few minutes can bury inhabited areas.
4. REAR (NORTH) FACADE OF THE UPPER FALLS GATE HOUSE. ...
4. REAR (NORTH) FACADE OF THE UPPER FALLS GATE HOUSE. - Washington Water Power Spokane River Upper Falls Hydroelectric Development, Gate House, Spokane River, approximately 0.5 mile northeast of intersection of Spokane Falls Boulevard & Post Street, Spokane, Spokane County, WA
Milagro Limits and HAWC Sensitivity for the Rate-Density of Evaporating Primordial Black Holes
NASA Technical Reports Server (NTRS)
Abdo, A. A.; Abeysekara, A. U.; Alfaro, R.; Allen, B.T.; Alvarez, C.; Alvarez, J. D.; Arceo, R.; Arteaga-Velazquez, J. C.; Aune, T.; Ayala Solares, H. A.;
2014-01-01
Primordial Black Holes (PBHs) are gravitationally collapsed objects that may have been created by density fluctuations in the early universe and could have arbitrarily small masses down to the Planck scale. Hawking showed that due to quantum effects, a black hole has a temperature inversely proportional to its mass and will emit all species of fundamental particles thermally. PBHs with initial masses of approximately 5.0 x 10 (sup 14) grams should be expiring in the present epoch with bursts of high-energy particles, including gamma radiation in the gigaelectronvolt - teraelectronvolt energy range. The Milagro high energy observatory, which operated from 2000 to 2008, is sensitive to the high end of the PBH evaporation gamma-ray spectrum. Due to its large field-of-view, more than 90 percent duty cycle and sensitivity up to 100 teraelectronvolt gamma rays, the Milagro observatory is well suited to perform a search for PBH bursts. Based on a search on the Milagro data, we report new PBH burst rate density upper limits over a range of PBH observation times. In addition, we report the sensitivity of the Milagro successor, the High Altitude Water Cherenkov (HAWC) observatory, to PBH evaporation events.
NASA Astrophysics Data System (ADS)
Wu, Huiting; He, Weihong; Weldon, Elizabeth A.
2018-04-01
Analysis of the Permian-Triassic palaeocommunities from basinal facies in South China provides an insight into the environmental deterioration occurring in the prelude to the mass extinction event. Quantitative and multivariate analyses on three brachiopod palaeocommunities from the Changhsingian to the earliest Triassic in basinal facies in South China have been undertaken in this study. Although the end-Permian extinction has been proved to be a one-stepped event, ecological warning signals appeared in the palaeocommunities long before the main pulse of the event. A brachiopod palaeocommunity turnover occurred in the upper part of the Clarkina changxingensis Zone, associated with a significant decrease of palaeocommunity diversity and brachiopod body size. During this turnover the dominant genera changed from Fusichonetes and Crurithyris (or/and Paracrurithyris) to the more competitive genus Crurithyris (or/and Paracrurithyris). The brachiopod palaeocommunity turnover was supposed to be triggered by the decreased marine primary productivity and increased volcanic activity. Moreover, such early warning signals are found not only in the deep-water siliceous facies, but also in the shallow-water clastic facies and carbonate rock facies in South China.
Milagro Limits and HAWC Sensitivity for the Rate-Density of Evaporating Primordial Black Holes
NASA Technical Reports Server (NTRS)
Abdo, A. A.; Abeysekara, A. U.; Alfaro, R.; Allen, B. T.; Alvarez, C.; Alvarez, J. D.; Arceo, R.; Arteaga-Velazquez, J. C.; Aune, T.; Ayala Solares, H. A.;
2014-01-01
Primordial Black Holes (PBHs) are gravitationally collapsed objects that may have been created by density fluctuations in the early universe and could have arbitrarily small masses down to the Planck scale. Hawking showed that due to quantum effects, a black hole has a temperature inversely proportional to its mass and will emit all species of fundamental particles thermally. PBHs with initial masses of approx.5.0 x 10(exp 14) g should be expiring in the present epoch with bursts of high-energy particles, including gamma radiation in the GeV-TeV energy range. The Milagro high energy observatory, which operated from 2000 to 2008, is sensitive to the high end of the PBH evaporation gamma-ray spectrum. Due to its large field-of-view, more than 90% duty cycle and sensitivity up to 100 TeV gamma rays, the Milagro observatory is well suited to perform a search for PBH bursts. Based on a search on the Milagro data, we report new PBH burst rate density upper limits over a range of PBH observation times. In addition, we report the sensitivity of the Milagro successor, the High Altitude Water Cherenkov (HAWC) observatory, to PBH evaporation events.
Seismic Signals of the 2014 Landslide near Oso, Washington
NASA Astrophysics Data System (ADS)
Allstadt, K.; Moran, S. C.; Malone, S. D.; Iverson, R. M.; George, D. L.
2014-12-01
The 22 March 2014 landslide near Oso, Washington rapidly moved a large volume of material (~8 million m^3), resulting in the efficient generation of seismic waves that were recorded over 350 km away. Analysis of these seismic signals significantly improves our understanding of the dynamics and timing of events. In contrast to the double couple mechanism of earthquakes, at long periods, the equivalent mechanism of a landslide is a single force. Inversion of the long-period waves for the forces exerted on the earth by the landslide yields a time-series that peaks at nearly 10^10 N and lasts ~1.5 minutes. This result, when combined with higher-frequency wave analysis, eyewitness reports, and field observations, implies a complex failure sequence. The earliest force pulses begin before the buildup in high-frequency energy, suggesting the slide began coherently before transitioning within a minute into the highly disrupted and destructive debris-avalanche flow that killed 43 people. This transition may have been due to a collapse of additional material that loaded the material downslope. Seismically observable "aftershock" landslides continued for weeks. The first and largest occurred a few minutes after the main failure sequence, and was followed by 15 more over the next ~4 hours that were observable at the closest seismic station (11 km away). Three USGS "spiders" equipped with GPS and seismic sensors were deployed by helicopter 10 days later as part of a monitoring effort. Due to their proximity, these seismometers detected signals from even minor collapses, some visually identified by human observers. This augmented network revealed interesting temporal patterns in the post-slide activity, which was dominated by sloughing of material from the headscarp, but also creep of the upper block of the failure mass at a rate of about 1 cm/day. This study shows the value of seismic analysis in landslide investigations to provide timing constraints and help improve our understanding of landslide dynamics.
Volcanic Stratigraphy of the Quaternary Rhyolite Plateau in Yellowstone National Park
Christiansen, Robert L.; Blank, H. Richard
1972-01-01
The volcanic sequence of the Quaternary Yellowstone plateau consists of rhyolites and basalts representing three volcanic cycles. The major events of each cycle were eruption of a voluminous ash-flow sheet and formation of a large collapse caldera. Lesser events of each cycle were eruption of precaldera and postcaldera rhyolitic lava flows and marginal basaltic lavas. The three major ash-flow sheets are named and designated in this report as formations within the Yellowstone Group. The lavas are assigned to newly named formations organized around the three ash-flow sheets of the Yellowstone Group to represent the volcanic cycles. Rocks of the first volcanic cycle comprise the precaldera Junction Butte Basalt and rhyolite of Broad Creek; the Huckleberry Ridge Tuff of the Yellowstone Group; and the postcaldera Lewis Canyon Rhyolite and basalt of The Narrows. Rocks of the second volcanic cycle do not crop out within Yellowstone National Park, and only the major unit, the Mesa Falls Tuff of the Yellowstone Group, is named here. The third volcanic cycle is represented by the precaldera Mount Jackson Rhyolite and Undine Falls Basalt; the Lava Creek Tuff of the Yellowstone Group; and the postcaldera Plateau Rhyolite and five post-Lava Creek basaltic sequences. Collapse to form the compound and resurgent Yellowstone caldera was related to eruption of the Lava Creek Tuff. The Plateau Rhyolite is divided into six members - the Mallard Lake, Upper Basin, Obsidian Creek, Central Plateau, Shoshone Lake Tuff, and Roaring Mountain Members; all but the Mallard Lake postdate resurgent doming of the caldera. The basalts are divided into the Swan Lake Flat Basalt, Falls River Basalt, basalt of Mariposa Lake, Madison River Basalt, and Osprey Basalt. Sediments are intercalated in the volcanic section below the Huckleberry Ridge and Mesa Falls Tuffs and within the Junction Butte Basalt, sediments and basalts of The Narrows, Undine Falls Basalt, Plateau Rhyolite, and Osprey Basalt.
NASA Astrophysics Data System (ADS)
Thouret, Jean-Claude; Gunnell, Yanni; Jicha, Brian R.; Paquette, Jean-Louis; Braucher, Régis
2017-12-01
Based on an 40Ar/39Ar- and U/Pb-based chronostratigraphy of ignimbrite sheets and the geomorphological features of watersheds, river profiles and slope deposits in the Ocoña-Cotahuasi-Marán (OCM) and Colca valleys of southwest Peru, we reconstruct the valley incision history of the western Central Andes over the last c. 25 Myr. We further document the Pleistocene and Holocene evolution of deep valleys on the basis of 14 10Be surface-exposure ages obtained on debris-avalanche deposits and river straths. The data suggest that uplift was gradual over the past 25 Myr, but accelerated after c. 9 Ma. Valley incision started around 11-9 Ma and accelerated between 5 and 4 Ma. Incision was followed by several pulses of valley cut-and-fill after 2.3 Ma. Evidence presented suggest that the post-5 Ma sequence of accelerated canyon incision probably resulted from a combination of drainage piracy from the Cordilleran drainage divide towards the Altiplano, accentuated flexural tilting of the Western Cordillera towards the SE, and increased rainfall on the Altiplano after late Miocene uplift of the Eastern Cordillera. The valley deepening and slope steepening driven by tectonic uplift gave rise to large occurrences of rockslope failure. The collapsed rock masses periodically obstructed the canyons, thus causing abrupt changes in local base levels and interfering with the steadiness of fluvial incision. As a result, channel aggradation has prevailed in the lower-gradient, U-shaped Pacific-rim canyons, whereas re-incision through landslide deposits has occurred more rapidly across the steeper V-shaped, upper valleys. Existing canyon knickpoints are currently arrested at the boundary between the plutonic bedrock and widespread outcrops of middle Miocene ignimbritic caprock, where groundwater sapping favouring rock collapse may be the dominant process driving headward erosion.
The diatom record from beneath the West Antarctic Ice Sheet and the global proxy perspective
NASA Technical Reports Server (NTRS)
Scherer, Reed P.
1993-01-01
Recent glaciological evaluation and modeling of the marine-based West Antarctic Ice Sheet (WAIS) support the possibility that the WAIS disintegrated during one or more Pleistocene interglacial period(s). The magnitude of sea level and oxygen isotope variation during certain late-Pleistocene interglacial periods is also consistent with the possibility of major retreat of the WAIS. Although oxygen isotopes from deep-sea sediments provide the best available proxy record for global ice volume (despite the ambiguities in the record), the source of ice volume changes must be hypothesized. Based on the intensity of interglacial isotopic shifts recorded in Southern Ocean marine sedimentary records, stage 11 (400,000 years ago) is the strongest candidate for WAIS collapse, but the records for stages 9, 7, and 5.5 are all consistent with the possibility of multiple late-Pleistocene collapses. Seismic reflection studies through the WAIS have revealed thick successions of strata with seismic characteristics comparable to upper Tertiary marine sediments. Small samples of glacial diamictons from beneath the ice sheet have been collected via hot-water drilled access holes. These sediments include mixed diatom assemblages of varying ages. Late-Miocene diatoms dominate many samples, probably reflecting marine deposition in West Antarctic basins prior to development of a dominantly glacial phase in West Antarctica. In addition to late-Miocene diatoms, samples from Upstream B (1988/89) contain rare post-Miocene diatoms, many of which imply deposition in the West Antarctic interior during one or more Pleistocene deglaciation periods. Age-diagnostic fossils in glacial sediments beneath ice sheets provide relatively coarse chronostratigraphic control, but they do contain direct evidence of regional deglaciation. Thus, sub-glacial till samples provide the evidence regarding the source of ice sheet variability seen in well-dated proxy records. Combined, these independent data sets can provide a more comprehensive and less speculative interpretation of the history of past glacial minima in currently glaciated polar regions.
ERIC Educational Resources Information Center
Hanratty, Brian
2017-01-01
Centred on a carefully chosen selection of Heaney's Troubles poems, this paper explores pedagogical opportunities that the poems present in the context of upper post-primary classrooms in Northern Ireland's divided schools. Five poems are evaluated in total. These are: "The Other Side", "A Constable calls", "The Toome…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kashlinsky, A., E-mail: Alexander.Kashlinsky@nasa.gov
LIGO's discovery of a gravitational wave from two merging black holes (BHs) of similar masses rekindled suggestions that primordial BHs (PBHs) make up the dark matter (DM). If so, PBHs would add a Poissonian isocurvature density fluctuation component to the inflation-produced adiabatic density fluctuations. For LIGO's BH parameters, this extra component would dominate the small-scale power responsible for collapse of early DM halos at z ≳ 10, where first luminous sources formed. We quantify the resultant increase in high- z abundances of collapsed halos that are suitable for producing the first generation of stars and luminous sources. The significantly increasedmore » abundance of the early halos would naturally explain the observed source-subtracted near-IR cosmic infrared background (CIB) fluctuations, which cannot be accounted for by known galaxy populations. For LIGO's BH parameters, this increase is such that the observed CIB fluctuation levels at 2–5 μ m can be produced if only a tiny fraction of baryons in the collapsed DM halos forms luminous sources. Gas accretion onto these PBHs in collapsed halos, where first stars should also form, would straightforwardly account for the observed high coherence between the CIB and unresolved cosmic X-ray background in soft X-rays. We discuss modifications possibly required in the processes of first star formation if LIGO-type BHs indeed make up the bulk or all of DM. The arguments are valid only if the PBHs make up all, or at least most, of DM, but at the same time the mechanism appears inevitable if DM is made of PBHs.« less
The nature of spherical collapse and a study of black hole dynamics
NASA Astrophysics Data System (ADS)
Nampalliwar, Sourabh
Gravitational waves and singularities are two of the most significant predictions of General Relativity. Binary systems are the most promising sources of gravitational waves that are expected to be detected with the current ground-based and upcoming space-based gravitational wave detectors. During the merger of binary compact objects, an important stage is the plunge. A small part of the gravitational waveform, it marks the end of early inspiral and determines the quasinormal ringing (QNR) of the final product of the merger. It is also the part of the waveform where most of the gravitational energy is released. But, unlike early inspiral and late ringdown, it is poorly understood in terms of phenomenology. This thesis introduces a novel approach combining the Fourier domain Green's function in the particle perturbation approximation and a simple model to understand this crucial stage. The resulting understanding is successful in explaining QNR for a Schwarzschild black hole and opens a new approach to understanding binary inspiral. It holds the promise of a much improved understanding, and improved efficiency in making astrophysical estimates of gravitational wave source strength. Singularities are known to be the ultimate fate of all massive stars undergoing gravitational collapse. The cosmic censorship hypothesis predicts that all these singularities are generically covered by event horizons, i.e., all collapsing stars, if they result in a singularity, end up as black holes. Although several theoretical examples of non-hidden (naked) singularities have been found, the question of the genericity of naked singularities is far from settled. This thesis presents a study of the causal structure of spherically symmetric models of dust collapse and its perturbations to investigate the genericity of naked singularities.
Radial nerve palsy in mid/distal humeral fractures: is early exploration effective?
Keighley, Geffrey; Hermans, Deborah; Lawton, Vidya; Duckworth, David
2018-03-01
Radial nerve palsies are a common complication with displaced distal humeral fractures. This case series examines the outcomes of early operative exploration and decompression of the nerve with fracture fixation with the view that this provides a solid construct for optimisation of nerve recovery. A total of 10 consecutive patients with a displaced distal humeral fracture and an acute radial nerve palsy were treated by the senior author by open reduction and internal fixation of the distal humerus and exploration and decompression of the radial nerve. Motor function and sensation of the radial nerve was assessed in the post-operative period every 2 months or until full recovery of the radial nerve function had occurred. All patients (100%) had recovery of motor and sensation function of their upper limb in the radial nerve distribution over a 12-month period. Recovery times ranged between 4 and 32 weeks, with the median time to recovery occurring at 26 weeks and the average time to full recovery being 22.9 weeks. Wrist extension recovered by an average of 3 months (range 2-26 weeks) and then finger extension started to recover 2-6 weeks after this. Disability of the arm, shoulder and hand scores ranged from 0 to 11.8 at greater than 1 year post-operatively. Our study demonstrated that early operative exploration of the radial nerve when performing an open stabilization of displaced distal humeral fractures resulted in a 100% recovery of the radial nerve. © 2017 Royal Australasian College of Surgeons.
Lenton, T. M.; Livina, V. N.; Dakos, V.; Van Nes, E. H.; Scheffer, M.
2012-01-01
We address whether robust early warning signals can, in principle, be provided before a climate tipping point is reached, focusing on methods that seek to detect critical slowing down as a precursor of bifurcation. As a test bed, six previously analysed datasets are reconsidered, three palaeoclimate records approaching abrupt transitions at the end of the last ice age and three models of varying complexity forced through a collapse of the Atlantic thermohaline circulation. Approaches based on examining the lag-1 autocorrelation function or on detrended fluctuation analysis are applied together and compared. The effects of aggregating the data, detrending method, sliding window length and filtering bandwidth are examined. Robust indicators of critical slowing down are found prior to the abrupt warming event at the end of the Younger Dryas, but the indicators are less clear prior to the Bølling-Allerød warming, or glacial termination in Antarctica. Early warnings of thermohaline circulation collapse can be masked by inter-annual variability driven by atmospheric dynamics. However, rapidly decaying modes can be successfully filtered out by using a long bandwidth or by aggregating data. The two methods have complementary strengths and weaknesses and we recommend applying them together to improve the robustness of early warnings. PMID:22291229
NASA Astrophysics Data System (ADS)
Kaniewski, D.; Paulissen, E.; Van Campo, E.; Weiss, H.; Otto, T.; Bretschneider, J.; Van Lerberghe, K.
2010-09-01
The alluvial deposits near Gibala-Tell Tweini provide a unique record of environmental history and food availability estimates covering the Late Bronze Age and the Early Iron Age. The refined pollen-derived climatic proxy suggests that drier climatic conditions occurred in the Mediterranean belt of Syria from the late 13th/early 12th centuries BC to the 9th century BC. This period corresponds with the time frame of the Late Bronze Age collapse and the subsequent Dark Age. The abrupt climate change at the end of the Late Bronze Age caused region-wide crop failures, leading towards socio-economic crises and unsustainability, forcing regional habitat-tracking. Archaeological data show that the first conflagration of Gibala occurred simultaneously with the destruction of the capital city Ugarit currently dated between 1194 and 1175 BC. Gibala redeveloped shortly after this destruction, with large-scale urbanization visible in two main architectural phases during the Early Iron Age I. The later Iron Age I city was destroyed during a second conflagration, which is radiocarbon-dated at circa 2950 cal yr BP. The data from Gibala-Tell Tweini provide evidence in support of the drought hypothesis as a triggering factor behind the Late Bronze Age collapse in the Eastern Mediterranean.
NASA Astrophysics Data System (ADS)
Liu, Junlai; Ji, Mo; Ni, Jinlong; Guan, Huimei; Shen, Liang
2017-04-01
The present study reports progress of our recent studies on the extensional structures in eastern North China craton and contiguous areas. We focus on characterizing and timing the formation/exhumation of the extensional structures, the Liaonan metamorphic core complex (mcc) and the Dayingzi basin from the Liaodong peninsula, the Queshan mcc, the Wulian mcc and the Zhucheng basin from the Jiaodong peninsula, and the Dashan magmatic dome within the Sulu orogenic belt. Magmatic rocks (either volcanic or plutonic) are ubiquitous in association with the tectonic extension (both syn- and post-kinematic). Evidence for crustal-mantle magma mixing are popular in many syn-kinematic intrusions. Geochemical analysis reveals that basaltic, andesitic to rhyolitic magmas were generated during the tectonic extension. Sr-Nd isotopes of the syn-kinematic magmatic rocks suggest that they were dominantly originated from ancient or juvenile crust partly with mantle signatures. Post-kinematic mafic intrusions with ages from ca. 121 Ma to Cenozoic, however, are of characteristic oceanic island basalts (OIB)-like trace element distribution patterns and relatively depleted radiogenic Sr-Nd isotope compositions. Integrated studies on the extensional structures, geochemical signatures of syn-kinematic magmatic rocks (mostly of granitic) and the tectono-magmatic relationships suggest that extension of the crust and the mantle lithosphere triggered the magmatisms from both the crust and the mantle. The Early Cretaceous tectono-magmatic evolution of the eastern Eurasian continent is governed by the PET in which the tectonic processes is subdivided into two stages, i.e. an early stage of tectonic extension, and a late stage of collapse of the extended lithosphere and transformation of lithospheric mantle. During the early stage, tectonic extension of the lithosphere led to detachment faulting in both the crust and mantle, resulted in the loss of some of the subcontinental roots, gave rise to the exhumation of the mccs, and triggered plutonic emplacement and volcanic eruptions of hybrid magmas. During the late stage, the nature of mantle lithosphere in North China was changed from the ancient SCLM to the juvenile SCLM. Extensional structures in eastern Eurasian continent provide a general architecture of the extensional tectonics of a rifted continent. Progressive extension resulted a sudden collaps of the crust (lithosphere) at ca. 130 to 120 Ma, associated with exhumation of mcc's and giant syn-kinematic magmatism, and post-kinematic magmatism. Parallel extension of both the crust and the mantle resulted in detachment faulting and magmatism, and also contributed to inhomogeneous thinning of the NCC lithosphere. Paleo-Pacific plate subduction and roll-back of the subducting oceanic plate contributed to the PET tectonic processes.
NASA Astrophysics Data System (ADS)
Rothery, D. A.
2012-04-01
Mercury is turning out to be a planet characterized by various kinds of endogenous hole (discounting impact craters), which are compared here. These include volcanic vents and collapse features on horizontal scales of tens of km, and smaller scale depressions ('hollows') associated with bright crater-floor deposits (BCFD). The BCFD hollows are tens of metres deep and kilometres or less across and are characteristically flat-floored, with steep, scalloped walls. Their form suggests that they most likely result from removal of surface material by some kind of mass-wasting process, probably associated with volume-loss caused by removal (via sublimation?) of a volatile component. These do not appear to be primarily a result of undermining. Determining the composition of the high-albedo bluish surface coating in BCFDs will be a key goal for BepiColombo instruments such as MIXS (Mercury Imaging Xray Spectrometer). In contrast, collapse features are non-circular rimless pits, typically on crater floors (pit-floor craters), whose morphology suggests collapse into void spaces left by magma withdrawal. This could be by drainage of either erupted lava (or impact melt) or of shallowly-intruded magma. Unlike the much smaller-scale BCFD hollows, these 'collapse pit' features tend to lack extensive flat floors and instead tend to be close to triangular in cross-section with inward slopes near to the critical angle of repose. The different scale and morphology of BCFD hollows and collapse pits argues for quite different modes of origin. However, BCFD hollows adjacent to and within the collapse pit inside Scarlatti crater suggest that the volatile material whose loss was responsible for the growth of the hollows may have been emplaced in association with the magma whose drainage caused the main collapse. Another kind of volcanic collapse can be seen within a 25 km-wide volcanic vent outside the southern rim of the Caloris basin (22.5° N, 146.1° E), on a 28 m/pixel MDIS NAC image from orbit. Although the vent itself may have been excavated partly by explosive volcanism, the most recent event is collapse of a 7 km wide zone in the south centre of the vent. The sharpness of features within this (unmuted either by regolith-forming processes or by fall of volcanic ejecta) suggests that this collapse considerably post-dates the rest of the vent interior. It could reflect a late-stage minor 'throat clearing' explosive eruption, but (in the absence of evidence of associated volcanic ejecta) more likely reflects collapse into a void within the volcanic conduit, itself a result of magma-drainage. A class of 'hole' that is so far conspicuous by its absence on Mercury is sinuous rilles (as opposed to much straighter tectonic grabens) or aligned skylights representing collapsed or partly-collapsed drained lava tubes. Tube-fed flows are to be expected during emplacement of volcanic plains, and it will be surprising if no examples are revealed on MESSENGER and BepiColombo high-resolution images.
The characteristic black hole mass resulting from direct collapse in the early Universe
NASA Astrophysics Data System (ADS)
Latif, M. A.; Schleicher, D. R. G.; Schmidt, W.; Niemeyer, J. C.
2013-12-01
Black holes of a billion solar masses are observed in the infant Universe a few hundred million years after the big bang. The direct collapse of protogalactic gas clouds in primordial haloes with Tvir ≥ 104 K provides the most promising way to assemble massive black holes. In this study, we aim to determine the characteristic mass scale of seed black holes and the time evolution of the accretion rates resulting from the direct collapse model. We explore the formation of supermassive black holes via cosmological large eddy simulations (LES) by employing sink particles and following their evolution for 20 000 yr after the formation of the first sink. As the resulting protostars were shown to have cool atmospheres in the presence of strong accretion, we assume here that UV feedback is negligible during this calculation. We confirm this result in a comparison run without sinks. Our findings show that black hole seeds with characteristic mass of 105 M⊙ are formed in the presence of strong Lyman-Werner flux which leads to an isothermal collapse. The characteristic mass is about two times higher in LES compared to the implicit large eddy simulations. The accretion rates increase with time and reach a maximum value of 10 M⊙ yr-1 after 104 yr. Our results show that the direct collapse model is clearly feasible as it provides the expected mass of the seed black holes.
Contraction Signatures toward Dense Cores in the Perseus Molecular Cloud
NASA Astrophysics Data System (ADS)
Campbell, J. L.; Friesen, R. K.; Martin, P. G.; Caselli, P.; Kauffmann, J.; Pineda, J. E.
2016-03-01
We report the results of an HCO+ (3-2) and N2D+ (3-2) molecular line survey performed toward 91 dense cores in the Perseus molecular cloud using the James Clerk Maxwell Telescope, to identify the fraction of starless and protostellar cores with systematic radial motions. We quantify the HCO+ asymmetry using a dimensionless asymmetry parameter δv, and identify 20 cores with significant blue or red line asymmetries in optically thick emission indicative of collapsing or expanding motions, respectively. We separately fit the HCO+ profiles with an analytic collapse model and determine contraction (expansion) speeds toward 22 cores. Comparing the δv and collapse model results, we find that δv is a good tracer of core contraction if the optically thin emission is aligned with the model-derived systemic velocity. The contraction speeds range from subsonic (0.03 km s-1) to supersonic (0.4 km s-1), where the supersonic contraction speeds may trace global rather than local core contraction. Most cores have contraction speeds significantly less than their free-fall speeds. Only 7 of 28 starless cores have spectra well-fit by the collapse model, which more than doubles (15 of 28) for protostellar cores. Starless cores with masses greater than the Jeans mass (M/MJ > 1) are somewhat more likely to show contraction motions. We find no trend of optically thin non-thermal line width with M/MJ, suggesting that any undetected contraction motions are small and subsonic. Most starless cores in Perseus are either not in a state of collapse or expansion, or are in a very early stage of collapse.
Geomagnetic responses to the solar wind and the solar activity
NASA Technical Reports Server (NTRS)
Svalgaard, L.
1975-01-01
Following some historical notes, the formation of the magnetosphere and the magnetospheric tail is discussed. The importance of electric fields is stressed and the magnetospheric convection of plasma and magnetic field lines under the influence of large-scale magnetospheric electric fields is outlined. Ionospheric electric fields and currents are intimately related to electric fields and currents in the magnetosphere and the strong coupling between the two regions is discussed. The energy input of the solar wind to the magnetosphere and upper atmosphere is discussed in terms of the reconnection model where interplanetary magnetic field lines merge or connect with the terrestrial field on the sunward side of the magnetosphere. The merged field lines are then stretched behind earth to form the magnetotail so that kinetic energy from the solar wind is converted into magnetic energy in the field lines in the tail. Localized collapses of the crosstail current, which is driven by the large-scale dawn/dusk electric field in the magnetosphere, divert part of this current along geomagnetic field lines to the ionosphere, causing substorms with auroral activity and magnetic disturbances. The collapses also inject plasma into the radiation belts and build up a ring current. Frequent collapses in rapid succession constitute the geomagnetic storm.
Viscous flow past a collapsible channel as a model for self-excited oscillation of blood vessels.
Tang, Chao; Zhu, Luoding; Akingba, George; Lu, Xi-Yun
2015-07-16
Motivated by collapse of blood vessels for both healthy and diseased situations under various circumstances in human body, we have performed computational studies on an incompressible viscous fluid past a rigid channel with part of its upper wall being replaced by a deformable beam. The Navier-Stokes equations governing the fluid flow are solved by a multi-block lattice Boltzmann method and the structural equation governing the elastic beam motion by a finite difference method. The mutual coupling of the fluid and solid is realized by the momentum exchange scheme. The present study focuses on the influences of the dimensionless parameters controlling the fluid-structure system on the collapse and self-excited oscillation of the beam and fluid dynamics downstream. The major conclusions obtained in this study are described as follows. The self-excited oscillation can be intrigued by application of an external pressure on the elastic portion of the channel and the part of the beam having the largest deformation tends to occur always towards the end portion of the deformable wall. The blood pressure and wall shear stress undergo significant variations near the portion of the greatest oscillation. The stretching motion has the most contribution to the total potential elastic energy of the oscillating beam. Copyright © 2015 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Xu, Wei; Qiu, Nansheng; Wang, Ye; Chang, Jian
2018-01-01
The Meso-Cenozoic lithospheric thermal-rheological structure and lithospheric strength evolution of the Jiyang sub-basin were modeled using thermal history, crustal structure, and rheological parameter data. Results indicate that the thermal-rheological structure of the Jiyang sub-basin has exhibited obvious rheological stratification and changes over time. During the Early Mesozoic, the uppermost portion of the upper crust, middle crust, and the top part of the upper mantle had a thick brittle layer. During the early Early Cretaceous, the top of the middle crust's brittle layer thinned because of lithosphere thinning and temperature increase, and the uppermost portion of the upper mantle was almost occupied by a ductile layer. During the late Early Cretaceous, the brittle layer of the middle crust and the upper mantle changed to a ductile one. Then, the uppermost portion of the middle crust changed to a thin brittle layer in the late Cretaceous. During the early Paleogene, the thin brittle layer of the middle crust became even thinner and shallower under the condition of crustal extension. Currently, with the decrease in lithospheric temperature, the top of the upper crust, middle crust, and the uppermost portion of the upper mantle are of a brittle layer. The total lithospheric strength and the effective elastic thickness ( T e) in Meso-Cenozoic indicate that the Jiyang sub-basin experienced two weakened stages: during the late Early Cretaceous and the early Paleogene. The total lithospheric strength (approximately 4-5 × 1013 N m-1) and T e (approximately 50-60 km) during the Early Mesozoic was larger than that after the Late Jurassic (2-7 × 1012 N m-1 and 19-39 km, respectively). The results also reflect the subduction, and rollback of Pacific plate is the geodynamic mechanism of the destruction of the eastern North China Craton.
Antualpa, Kizzy; Aoki, Marcelo Saldanha; Moreira, Alexandre
2018-05-01
This study examined the effect of a 4-week intensified training (IT) period, followed by a 2-week tapering period (TP), on salivary immunoglobulin A (SIgA), salivary cortisol, and the severity of upper respiratory tract infection symptoms in 23 rhythmic gymnasts [12.1 (2.6) y; 143.9 (13.7) cm; 37.2 (9.4) kg]. Saliva sampling was conducted at pre- and post-IT, and post-TP (analyzed using enzyme-linked immunosorbent assay). The Wisconsin Upper Respiratory Symptom Survey (WURSS-21) questionnaire was completed daily to analyze the severity of upper respiratory tract infection symptoms. The session rating of the perceived exertion was used to determine the internal training load and the acute:chronic workload ratio. A higher SIgA concentration [SIgA abs (μg/mL); F = 7.6; P = .001] for post-IT [234 (104)] versus pre-IT [173 (91)], and post-TP [182 (70)], and a higher SIgA secretion rate [SIgA rate (μg/min); F = 3.4; P = .04] for post-IT [69 (28)] versus pre-IT [55 (27)], and post-TP [58 (22)] were observed. No significant change was observed for cortisol (F = 0.81; P = .45) or for the severity of upper respiratory tract infection symptoms (χ 2 = 2.81; P = .24). Internal training load was higher during IT (vs TP; effect size = 2.37). The acute:chronic workload for the IT weeks varied from 1.2 (0.3) to 1.4 (0.3). These results suggest that a 4-week IT may temporarily augment the oral mucosal immunity, and an acute:chronic workload of 1.2-1.4 seems to be a safe approach to periodized training loads in youth rhythmic gymnasts.
Upper crustal densities derived from sea floor gravity measurements: Northern Juan De Fuca Ridge
Holmes, Mark L.; Johnson, H. Paul
1993-01-01
A transect of sea floor gravity stations has been analyzed to determine upper crustal densities on the Endeavour segment of the northern Juan de Fuca Ridge. Data were obtained using ALVIN along a corridor perpendicular to the axis of spreading, over crustal ages from 0 to 800,000 years. Calculated elevation factors from the gravity data show an abrupt increase in density with age (distance) for the upper 200 m of crust. This density change is interpreted as a systematic reduction in bulk porosity of the upper crustal section, from 23% for the axial ridge to 10% for the off-axis flanking ridges. The porosity decrease is attributed to the collapse and filling of large-scale voids as the abyssal hills move out of the crustal formation zone. Forward modeling of a plausible density structure for the near-axis region agrees with the observed anomaly data only if the model includes narrow, along-strike, low-density regions adjacent to both inner and outer flanks of the abyssal hills. The required low density zones could be regions of systematic upper crustal fracturing and faulting that were mapped by submersible observers and side-scan sonar images, and whose presence was suggested by the distribution of heat flow data in the same area.
NASA Astrophysics Data System (ADS)
Koehl, Jean-Baptiste P.; Bergh, Steffen G.; Henningsen, Tormod; Faleide, Jan Inge
2018-03-01
The SW Barents Sea margin experienced a pulse of extensional deformation in the Middle-Late Devonian through the Carboniferous, after the Caledonian Orogeny terminated. These events marked the initial stages of formation of major offshore basins such as the Hammerfest and Nordkapp basins. We mapped and analyzed three major fault complexes, (i) the Måsøy Fault Complex, (ii) the Rolvsøya fault, and (iii) the Troms-Finnmark Fault Complex. We discuss the formation of the Måsøy Fault Complex as a possible extensional splay of an overall NE-SW-trending, NW-dipping, basement-seated Caledonian shear zone, the Sørøya-Ingøya shear zone, which was partly inverted during the collapse of the Caledonides and accommodated top-NW normal displacement in Middle to Late Devonian-Carboniferous times. The Troms-Finnmark Fault Complex displays a zigzag-shaped pattern of NNE-SSW- and ENE-WSW-trending extensional faults before it terminates to the north as a WNW-ESE-trending, NE-dipping normal fault that separates the southwesternmost Nordkapp basin in the northeast from the western Finnmark Platform and the Gjesvær Low in the southwest. The WNW-ESE-trending, margin-oblique segment of the Troms-Finnmark Fault Complex is considered to represent the offshore prolongation of a major Neoproterozoic fault complex, the Trollfjorden-Komagelva Fault Zone, which is made of WNW-ESE-trending, subvertical faults that crop out on the island of Magerøya in NW Finnmark. Our results suggest that the Trollfjorden-Komagelva Fault Zone dies out to the northwest before reaching the western Finnmark Platform. We propose an alternative model for the origin of the WNW-ESE-trending segment of the Troms-Finnmark Fault Complex as a possible hard-linked, accommodation cross fault that developed along the Sørøy-Ingøya shear zone. This brittle fault decoupled the western Finnmark Platform from the southwesternmost Nordkapp basin and merged with the Måsøy Fault Complex in Carboniferous times. Seismic data over the Gjesvær Low and southwesternmost Nordkapp basin show that the low-gravity anomaly observed in these areas may result from the presence of Middle to Upper Devonian sedimentary units resembling those in Middle Devonian, spoon-shaped, late- to post-orogenic collapse basins in western and mid-Norway. We propose a model for the formation of the southwesternmost Nordkapp basin and its counterpart Devonian basin in the Gjesvær Low by exhumation of narrow, ENE-WSW- to NE-SW-trending basement ridges along a bowed portion of the Sørøya-Ingøya shear zone in the Middle to Late Devonian-early Carboniferous. Exhumation may have involved part of a large-scale metamorphic core complex that potentially included the Lofoten Ridge, the West Troms Basement Complex and the Norsel High. Finally, we argue that the Sørøya-Ingøya shear zone truncated and decapitated the Trollfjorden-Komagelva Fault Zone during the Caledonian Orogeny and that the western continuation of the Trollfjorden-Komagelva Fault Zone was mostly eroded and potentially partly preserved in basement highs in the SW Barents Sea.
A post-marketing observational study to assess the safety of mibefradil in the community in England.
Riley, J; Wilton, L V; Shakir, S A W
2002-06-01
To conduct a post-marketing observational cohort study to assess the safety of mibefradil in the community, using Prescription-Event Monitoring (PEM). Data were collected and analyzed on patients prescribed mibefradil by 1,996 General Practitioners (GPs) throughout England. Incidence densities were calculated for all reported events and selected events were followed-up by means of further questionnaires. The study was terminated early due to the voluntary withdrawal of mibefradil from the market because of potential drug interactions. A cohort of 3,085 patients was recruited, with a mean age of 64.5 years. The major indication for use was hypertension (55% of the cohort), the indication was not specified in 33% of patients. 80% of GPs expressing an opinion rated mibefradil as effective. The major reason for stopping was withdrawal from the market (2,342 patients). The commonest reported adverse events and reasons for stopping were malaise/lassitude, dizziness, edema and headache. Seven clinically serious reports of bradycardia/collapse were considered to be possible adverse drug reactions (ADRs) to mibefradil. All were in the elderly (> 65 years), 6 were considered to be a result of possible drug interactions. In total, 11 possible drug interactions occurred. Nine (8 reports of bradycardia and 1 of syncope) involved beta-blockers. Another, a report of collapse and severe bradycardia, occurred in a patient who had started a dihydropyridine calcium channel blocker within 24 hours of stopping mibefradil and the other was a report of palpitations and dyspnea in a patient on concomitant digoxin and sotalol. None of the 53 deaths occurring during the study was attributed to mibefradil. Mibefradil was only available on the UK market for 6 months before it was withdrawn from the market because of potential drug interactions. With respect to the reasons leading to its withdrawal, in this cohort of 3,085 patients, 11 possible drug interactions were detected (6 clinically significant) involving beta-blockers, a dihydropyridine calcium channel blocker and digoxin and/or sotalol. PEM can contribute to the understanding of ADRs caused by drug interactions occurring in real-life settings.
Isotropic neutrino flux from supernova explosions in the universe
NASA Astrophysics Data System (ADS)
Petkov, V. B.
2018-01-01
Neutrinos of all types are emitted from the gravitational collapse of massive star cores, and have been amassed in the Universe throughout the history of evolution of galaxies. The isotropic and stable flux of these neutrinos is a source of information on the spectra of neutrinos from individual supernovae and on their redshift distribution. The prospects for detecting the isotropic neutrino flux with the existing and upcoming experimental facilities and the current upper limits are discussed in this paper.
NASA Astrophysics Data System (ADS)
Miller, Craig A.; Currenti, Gilda; Hamling, Ian; Williams-Jones, Glyn
2018-05-01
Fluid transfer and ground deformation at hydrothermal systems occur both as a precursor to, or as a result of, an eruption. Typically studies focus on pre-eruption changes to understand the likelihood of unrest leading to eruption; however, monitoring post-eruption changes is important for tracking the return of the system towards background activity. Here we describe processes occurring in a hydrothermal system following the 2012 eruption of Upper Te Maari crater on Mt Tongariro, New Zealand, from observations of microgravity change and deformation. Our aim is to assess the post-eruption recovery of the system, to provide a baseline for long-term monitoring. Residual microgravity anomalies of up to 92 ± 11 μGal per year are accompanied by up to 0.037 ± 0.01 m subsidence. We model microgravity changes using analytic solutions to determine the most likely geometry and source location. A multiobjective inversion tests whether the gravity change models are consistent with the observed deformation. We conclude that the source of subsidence is separate from the location of mass addition. From this unusual combination of observations, we develop a conceptual model of fluid transfer within a condensate layer, occurring in response to eruption-driven pressure changes. We find that depressurisation drives the evacuation of pore fluid, either exiting the system completely as vapour through newly created vents and fumaroles, or migrating to shallower levels where it accumulates in empty pore space, resulting in positive gravity changes. Evacuated pores then collapse, causing subsidence. In addition we find that significant mass addition occurs from influx of meteoric fluids through the fractured hydrothermal seal. Long-term combined microgravity and deformation monitoring will allow us to track the resealing and re-pressurisation of the hydrothermal system and assess what hazard it presents to thousands of hikers who annually traverse the volcano, within 2 km of the eruption site.
Yeldan, Ipek; Huseyınsınoglu, Burcu Ersoz; Akıncı, Buket; Tarakcı, Ela; Baybas, Sevim; Ozdıncler, Arzu Razak
2015-11-01
[Purpose] The aim of the study was to evaluate the effects of a very early mirror therapy program on functional improvement of the upper extremity in acute stroke patients. [Subjects] Eight stroke patients who were treated in an acute neurology unit were included in the study. [Methods] The patients were assigned alternatively to either the mirror therapy group receiving mirror therapy and neurodevelopmental treatment or the neurodevelopmental treatment only group. The primary outcome measures were the upper extremity motor subscale of the Fugl-Meyer Assessment, Motricity Index upper extremity score, and the Stroke Upper Limb Capacity Scale. Somatosensory assessment with the Ayres Southern California Sensory Integration Test, and the Barthel Index were used as secondary outcome measures. [Results] No statistically significant improvements were found for any measures in either group after the treatment. In terms of minimally clinically important differences, there were improvements in Fugl-Meyer Assessment and Barthel Index in both mirror therapy and neurodevelopmental treatment groups. [Conclusion] The results of this pilot study revealed that very early mirror therapy has no additional effect on functional improvement of upper extremity function in acute stroke patients. Multicenter trials are needed to determine the results of early application of mirror therapy in stroke rehabilitation.
NASA Astrophysics Data System (ADS)
Frau, Camille; Pictet, Antoine; Spangenberg, Jorge E.; Masse, Jean-Pierre; Tendil, Anthony J.-B.; Lanteaume, Cyprien
2017-08-01
Our contribution presents an integrated litho-, bio- and chemostratigraphic study of the best-preserved outcrops of the post-Urgonian marly cover (A1 unit) of the North Provence carbonate platform. The study of the rich ammonite fauna from the Apt-Gargas area (SE Vaucluse) confirms that the A1 unit is older than previously assumed and dated to the upper (but non-uppermost) part of the lower Aptian Deshayesites forbesi Zone of the Mediterranean standard zonation. This interval is assigned to the lower part of the Roloboceras hambrovi Subzone as defined in the present contribution which is time equivalent to the spreading of the OAE 1a. Microfossil occurrences previously documented in the A1 unit are consistent with our ammonite-age calibration. Unfortunately, the curves of the carbon and oxygen stable isotopes exhibit a correlative signal probably caused by an early diagenetic overprint which questions the previous use of the C-isotope signal for precise chronostratigraphic correlation with respect to the OAE 1a excursion. The top of the A1 unit is marked by a burrowed firmground locally infilled and capped by glauconite-rich sandy marls which grade into the blue-grey muddy marls of the overlying A2 unit. The hiatus associated to this discontinuity is equivalent to the culmination of the OAE 1a, including the uppermost D. forbesi Zone (= upper R. hambrovi Subzone as herein defined) and the lower D. deshayesi Zone. The revised calibration of the post-Urgonian marl implies that the ammonite-age calibration of the North Provence carbonate platform should be revised and questions the timing and driving mechanisms of its stepwise demise.
1. CONTEXTUAL VIEW OF THE UPPER FALLS GATE HOUSE, FOREBAY ...
1. CONTEXTUAL VIEW OF THE UPPER FALLS GATE HOUSE, FOREBAY IN FOREGROUND, LOOKING NORTH. - Washington Water Power Spokane River Upper Falls Hydroelectric Development, Gate House, Spokane River, approximately 0.5 mile northeast of intersection of Spokane Falls Boulevard & Post Street, Spokane, Spokane County, WA
Assessment of the suitability of trees for brownfields reuse in the post-mining landscape
NASA Astrophysics Data System (ADS)
Mec, J.; Lokajickova, B.; Sotkova, N.; Svehlakova, H.; Stalmachova, B.
2017-10-01
The post-mining landscape of Upper Silesian is deterioration of the original landscape caused by underground coal mining. There are huge ecosystems changes, which have been reclaimed by nature-friendly procedures. The aim of the work is to evaluate the suitability of selected trees for reuse of brownfields in this landscape and proposals for reclamation in the interest areas of Upper Silesian.
Sandberg, C.A.; Morrow, J.R.; Poole, F.G.; Ziegler, W.
2003-01-01
The classic type section of the Devils Gate Limestone at Devils Gate Pass is situated on the eastern slope of a proto-Antler forebulge that resulted from convergence of the west side of the North American continent with an ocean plate. The original Late Devonian forebulge, the site of which is now located between Devils Gate Pass and the Northern Antelope Range, separated the continental-rise to deep-slope Woodruff basin on the west from the backbulge Pilot basin on the east. Two connections between these basins are recorded by deeper water siltstone beds at Devils Gate; the older one is the lower tongue of the Woodruff Formation, which forms the basal unit of the upper member of the type Devils Gate, and the upper one is the overlying, thin lower member of the Pilot Shale. The forebulge and the backbulge Pilot basin originated during the middle Frasnian (early Late Devonian) Early hassi Zone, shortly following the Alamo Impact within the punctata Zone in southern Nevada. Evidence of this impact is recorded by coeval and reworked shocked quartz grains in the Northern Antelope Range and possibly by a unique bypass-channel or megatsunami-uprush sandy diamictite within carbonate-platform rocks of the lower member of the type Devils Gate Limestone. Besides the Alamo Impact and three regional events, two other important global events are recorded in the Devils Gate section. The semichatovae eustatic rise, the maximum Late Devonian flooding event, coincides with the sharp lithogenetic change at the discordant boundary above the lower member of the Devils Gate Limestone. Most significantly, the Devils Gate section contains the thickest and most complete rock record in North America across the late Frasnian linguiformis Zone mass extinction event. Excellent exposures include not only the extinction shale, but also a younger. Early triangularis Zone tsunamite breccia, produced by global collapse of carbonate platforms during a shallowing event that continued into the next younger Famennian Stage. The Northern Antelope Range section is located near the top of the west side of the proto-Antler forebulge. Because of its unusual, tectonically active location, unmatched at any other Nevada localities, this section records only four regional and global events during a timespan slightly longer than that of the Devils Gate section. The global semichatovae rise and late Frasnian mass extinction event are largely masked because of the depositional complexities resulting from this location.
NASA Astrophysics Data System (ADS)
Stewart, D. M.; Silins, U.; Emelko, M.; Stone, M.
2016-12-01
While forest harvesting effects on nitrogen (N) cycling and watershed nitrogen export are generally well documented, the factors that govern variation in post-disturbance watershed export of N after forest disturbance across different hydro-climatic regions as less well understood. Factors that regulate the coupling of N dynamics on hillslopes with receiving streams are not well understood in steeper mountainous terrain where strong spatial variation in radiation, temperature, and nutrient turnover potentially govern post-disturbance catchment exports of N. Objectives of this study were to explore the relative influence of variation in hillslope position (upper vs lower) and radiation load among contrasting south- and north-facing hillslope positions in regulating soil nitrogen turnover and mobile nitrogen (NO-3) after clear-cut logging in the Rocky Mountains of south-west Alberta, Canada. A combined approach employing replicated measurement of key soil N species in soil solution (available N, using ion exchange membranes) and shallow hillslope pore water N (using suction lysimeters) was used to explore how variation in hillslope position and radiation load (S/N facing) after clear-cut logging of a Lodgepole pine dominated Rocky Mountain watershed in southwest Alberta. These were compared to parallel measurements in unharvested (reference) hillslopes in the same watershed. Logging was completed in 2015 with measurements of soil and shallow groundwater N at 6 week intervals from April to Oct. 2016. Compared to other types of forest disturbance (i.e. wildfire) common in this region, clear-cut harvesting did not produce a large impact on both surface and deeper available N for reference and harvested stands. In particular, early season available NO-3 is enriched in upper stands, while other factors showed less of an effect. Overall, results provide important insights into how disturbance effects on mobile N among hillslopes of contrasting energy gain, soil moisture, and thermal regimes interact in driving post-disturbance N export in steep, mountainous terrain.
NASA Astrophysics Data System (ADS)
Robertson, Alastair; Unlügenç, Ülvi Can; İnan, Nurdan; Ta ṡli, Kemal
2004-01-01
The Mid-Tertiary (Mid-Eocene to earliest Miocene) Misis-Andırın Complex documents tectonic-sedimentary processes affecting the northerly, active margin of the South Tethys (Neotethys) in the easternmost Mediterranean region. Each of three orogenic segments, Misis (in the SW), Andırın (central) and Engizek (in the NE) represent parts of an originally continuous active continental margin. A structurally lower Volcanic-Sedimentary Unit includes Late Cretaceous arc-related extrusives and their Lower Tertiary pelagic cover. This unit is interpreted as an Early Tertiary remnant of the Mesozoic South Tethys. The overlying melange unit is dominated by tectonically brecciated blocks (>100 m across) of Mesozoic neritic limestone that were derived from the Tauride carbonate platform to the north, together with accreted ophiolitic material. The melange matrix comprises polymict debris flows, high- to low-density turbidites and minor hemipelagic sediments. The Misis-Andırın Complex is interpreted as an accretionary prism related to the latest stages of northward subduction of the South Tethys and diachronous continental collision of the Tauride (Eurasian) and Arabian (African) plates during Mid-Eocene to earliest Miocene time. Slivers of Upper Cretaceous oceanic crust and its Early Tertiary pelagic cover were accreted, while blocks of Mesozoic platform carbonates slid from the overriding plate. Tectonic mixing and sedimentary recycling took place within a trench. Subduction culminated in large-scale collapse of the overriding (northern) margin and foundering of vast blocks of neritic carbonate into the trench. A possible cause was rapid roll back of dense downgoing Mesozoic oceanic crust, such that the accretionary wedge taper was extended leading to gravity collapse. Melange formation was terminated by underthrusting of the Arabian plate from the south during earliest Miocene time. Collision was diachronous. In the east (Engizek Range and SE Anatolia) collision generated a Lower Miocene flexural basin infilled with turbidites and a flexural bulge to the south. Miocene turbiditic sediments also covered the former accretionary prism. Further west (Misis Range) the easternmost Mediterranean remained in a pre-collisional setting with northward underthrusting (incipient subduction) along the Cyprus arc. The Lower Miocene basins to the north (Misis and Adana) indicate an extensional (to transtensional) setting. The NE-SW linking segment (Andırın) probably originated as a Mesozoic palaeogeographic offset of the Tauride margin. This was reactivated by strike-slip (and transtension) during Later Tertiary diachronous collision. Related to on-going plate convergence the former accretionary wedge (upper plate) was thrust over the Lower Miocene turbiditic basins in Mid-Late Miocene time. The Plio-Quaternary was dominated by left-lateral strike-slip along the East Anatolian transform fault and also along fault strands cutting the Misis-Andırın Complex.
Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma
Halaoui, Ruba; Rejon, Carlis; Chatterjee, Sudipa June; Szymborski, Joseph; Meterissian, Sarkis; Muller, William J.; Omeroglu, Atilla; McCaffrey, Luke
2017-01-01
Epithelial cancers (carcinoma) account for 80%–90% of all cancers. The development of carcinoma is associated with disrupted epithelial organization and solid ductal structures. The mechanisms underlying the morphological development of carcinoma are poorly understood, but it is thought that loss of cell polarity is an early event. Here we report the characterization of the development of human breast lesions leading to carcinoma. We identified a unique mechanism that generates solid ducts in carcinoma through progressive loss of polarity and collapse of the luminal architecture. This program initiates with asymmetric divisions of polarized cells that generate a stratified epithelium containing both polarized and depolarized cells. Stratified regions form cords that penetrate into the lumen, subdividing it into polarized secondary lumina. The secondary lumina then collapse with a concomitant decrease in RhoA and myosin II activity at the apical membrane and ultimately lose apical–basal polarity. By restoring RhoA activity in mice, ducts maintained lumen and cell polarity. Notably, disrupted tissue architecture through luminal collapse was reversible, and ducts with a lumen were re-established after oncogene suppression in vivo. This reveals a novel and common mechanism that contributes to carcinoma development by progressively disrupting cell and tissue organization. PMID:28887414
Dynein pulling forces counteract lamin-mediated nuclear stability during nuclear envelope repair
Penfield, Lauren; Wysolmerski, Brian; Mauro, Michael; Farhadifar, Reza; Martinez, Michael A.; Biggs, Ronald; Wu, Hai-Yin; Broberg, Curtis; Needleman, Daniel; Bahmanyar, Shirin
2018-01-01
Recent work done exclusively in tissue culture cells revealed that the nuclear envelope (NE) ruptures and repairs in interphase. The duration of NE ruptures depends on lamins; however, the underlying mechanisms and relevance to in vivo events are not known. Here, we use the Caenorhabditis elegans zygote to analyze lamin’s role in NE rupture and repair in vivo. Transient NE ruptures and subsequent NE collapse are induced by weaknesses in the nuclear lamina caused by expression of an engineered hypomorphic C. elegans lamin allele. Dynein-generated forces that position nuclei enhance the severity of transient NE ruptures and cause NE collapse. Reduction of dynein forces allows the weakened lamin network to restrict nucleo–cytoplasmic mixing and support stable NE recovery. Surprisingly, the high incidence of transient NE ruptures does not contribute to embryonic lethality, which is instead correlated with stochastic chromosome scattering resulting from premature NE collapse, suggesting that C. elegans tolerates transient losses of NE compartmentalization during early embryogenesis. In sum, we demonstrate that lamin counteracts dynein forces to promote stable NE repair and prevent catastrophic NE collapse, and thus provide the first mechanistic analysis of NE rupture and repair in an organismal context. PMID:29386297
NASA Astrophysics Data System (ADS)
Halevi, Goni; Mösta, Philipp
2018-06-01
We investigate r-process nucleosynthesis in three-dimensional general relativistic magnetohydrodynamic simulations of jet-driven supernovae resulting from rapidly rotating, strongly magnetized core-collapse. We explore the effect of misaligning the pre-collapse magnetic field with respect to the rotation axis by performing four simulations: one aligned model and models with 15°, 30°, and 45° misalignments. The simulations we present employ a microphysical finite-temperature equation of state and a leakage scheme that captures the overall energetics and lepton number exchange due to post-bounce neutrino emission and absorption. We track the thermodynamic properties of the ejected material with Lagrangian tracer particles and analyse its composition with the nuclear reaction network SKYNET. By using different neutrino luminosities in post-processing the tracer data with SKYNET, we constrain the impact of uncertainties in neutrino luminosities. We find that, for the aligned model considered here, the use of an approximate leakage scheme results in neutrino luminosity uncertainties corresponding to a factor of 100-1000 uncertainty in the abundance of third peak r-process elements. Our results show that for misalignments of 30° or less, r-process elements are robustly produced as long as neutrino luminosities are reasonably low (≲ 5 × 1052 erg s-1). For a more extreme misalignment of 45°, we find the production of r-process elements beyond the second peak significantly reduced. We conclude that robust r-process nucleosynthesis in magnetorotational supernovae requires a progenitor stellar core with a large poloidal magnetic field component that is at least moderately (within ˜30°) aligned with the rotation axis.
Mochizuki, Susumu; Minami, Eiichi; Nishizawa, Yoko
2015-12-01
The rice blast fungus Magnaporthe oryzae grows inside living host cells. Cytological analyses by live-cell imaging have revealed characteristics of the biotrophic invasion, particularly the extrainvasive hyphal membrane (EIHM) originating from the host plasma membrane and a host membrane-rich structure, biotrophic interfacial complex (BIC). Here, we observed rice subcellular changes associated with invasive hyphal growth using various transformants expressing specifically localized fluorescent proteins. The invasive hyphae did not penetrate across but were surrounded by the host vacuolar membrane together with EIHM even after branching. High-resolution imaging of BICs revealed that the host cytosol was accumulated at BIC with aggregated EIHM and a symplastic effector, Pwl2, in a punctate form. The vacuolar membrane did not aggregate in but closely surrounded the BIC. A good correlation was observed between the early collapse of vacuoles and damage of invasive hyphae in the first-invaded cell. Furthermore, a newly developed, long-term imaging method has revealed that the central vacuole gradually shrank until collapse, which was caused by the hyphal invasion occurring earlier in the neighboring cells than in the first-invaded cells. These data suggest that M. oryzae may suppress host vacuole collapse during early infection stages for successful infection. © 2015 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.
Dependence of weak interaction rates on the nuclear composition during stellar core collapse
NASA Astrophysics Data System (ADS)
Furusawa, Shun; Nagakura, Hiroki; Sumiyoshi, Kohsuke; Kato, Chinami; Yamada, Shoichi
2017-02-01
We investigate the influences of the nuclear composition on the weak interaction rates of heavy nuclei during the core collapse of massive stars. The nuclear abundances in nuclear statistical equilibrium (NSE) are calculated by some equation of state (EOS) models including in-medium effects on nuclear masses. We systematically examine the sensitivities of electron capture and neutrino-nucleus scattering on heavy nuclei to the nuclear shell effects and the single-nucleus approximation. We find that the washout of the shell effect at high temperatures brings significant change to weak rates by smoothing the nuclear abundance distribution: the electron capture rate decreases by ˜20 % in the early phase and increases by ˜40 % in the late phase at most, while the cross section for neutrino-nucleus scattering is reduced by ˜15 % . This is because the open-shell nuclei become abundant instead of those with closed neutron shells as the shell effects disappear. We also find that the single-nucleus description based on the average values leads to underestimations of weak rates. Electron captures and neutrino coherent scattering on heavy nuclei are reduced by ˜80 % in the early phase and by ˜5 % in the late phase, respectively. These results indicate that NSE like EOS accounting for shell washout is indispensable for the reliable estimation of weak interaction rates in simulations of core-collapse supernovae.
Taveggia, Giovanni; Borboni, Alberto; Salvi, Lorena; Mulé, Chiara; Fogliaresi, Stefania; Villafañe, Jorge H; Casale, Roberto
2016-12-01
A prompt and effective physical and rehabilitation medicine approach is essential to obtain recovery of an impaired limb to prevent tendon shortening, spasticity and pain. Robot-assisted virtual reality intervention has been shown to be more effective than conventional interventions and achieved greater improvement in upper limb function. The aim of this study was to evaluate the effectiveness of robotic-assisted motion and activity in addition to PRM for the rehabilitation of the upper limb in post-stroke inpatients. Randomized controlled trial. Departments of Physical and Rehabilitation Medicine from three different hospitals (Sarnico, Brescia; Bergamo; Milan). A total of 54 patients and enrolled 23 men and 31 women with post-stroke hemiparesis, aged 18 to 80 years old, enrolled from July 2014 to February 2015. Of the 54 enrolled patients, 57% were female (mean age 71±12 years), and all had upper limb function deficit post-stroke. The experimental group received a passive mobilization of the upper limb through the robotic device ARMEO Spring and the control group received PRM for 6 consecutive weeks (5 days/week) in addition to traditional PRM. We assessed the impact on functional recovery (Functional Independence Measure [FIM] scale), strength (Motricity Index [MI]), spasticity (Modified Ashworth Scale [MAS]) and pain (Numeric Rating Pain Scale [NRPS]). All patients were evaluated by a blinded observer using the outcomes tests at enrollment (T0), after the treatment (T1) and at follow up 6 weeks later (T2). Both control and experimental groups evidenced an improvement of the outcomes after the treatment (MI, Ashworth and NRPS with P<0.05). The experimental group showed further improvements after the follow up (all outcomes with P<0.01). In the treatment of pain, disability and spasticity in upper limb after stroke, robot-assisted mobilization associated to PRM is as effective as traditional rehabilitation. Robot-assisted treatment has an impact on upper limb motor function in stroke patients.
Role of ice sheet dynamics in the collapse of the early-Holocene Laurentide Ice Sheet
NASA Astrophysics Data System (ADS)
Matero, I. S. O.; Gregoire, L. J.; Cornford, S. L.; Ivanovic, R. F.
2017-12-01
The last stage of the deglaciation of the Laurentide Ice Sheet (LIS) during the early Holocene Thermal Maximum ( 9000 to 7000 years ago) provides an analogy and insight to the possible responses of contemporary ice sheets in a warming climate. What makes LIS particularly interesting is that meltwater from the collapse of an ice saddle over Hudson Bay was recently shown to be the primary forcing for the period of abrupt northern hemisphere cooling known as the 8.2 ka event. The evolution of the LIS during this period was likely influenced by its interaction with marginal lakes and the ocean, and its major ice stream, which exported ice towards Hudson Strait. Accurately simulating the early Holocene LIS evolution thus requires a model such as BISICLES, capable of accurately and efficiently resolving ice stream dynamics and grounding line migration thanks to the combined use of higher order physics and adaptive mesh refinement. We drive the BISICLES model using a positive degree day mass balance scheme with monthly precipitation and temperature from the HadCM3 climate model under climatic conditions from 10,000 to 8,000 years ago. We test the effect of varying the initial topographies and ice thicknesses from different timeslices in the ICE-6Gc reconstruction. We also test different parameterisations for the basal friction based on the thicknesses of the underlying sediments. These simulations evaluate the role of the Hudson Strait ice stream, ice sheet dynamics and interactions with the adjacent proglacial Lake Agassiz and North Atlantic Ocean in the collapse of the LIS. Our results highlight that the choice of parameterisation for basal friction has major effects on ice sheet dynamics and evolution.
Balneotherapy in treatment of spastic upper limb after stroke.
Erceg-Rukavina, Tatjana; Stefanovski, Mihajlo
2015-02-01
After stroke, spasticity is often the main problem that prevents functional recovery. Pain occurs in up to 70% of patients during the first year post-stroke. A total of 70 patients (30 female and 45 male) mean age (65.67) participated in prospective, controlled study. ischaemic stroke, developed spasticity of upper limb, post-stroke interval <6 months. contraindications for balneotherapy and inability to follow commands. Experimental group (Ex) (n=35) was treated with sulphurous baths (31°-33°C) and controlled group (Co) with taped water baths, during 21 days. All patients were additionally treated with kinesitherapy and cryotherapy. The outcome was evaluated using Modified Ashworth scale for spasticity and VAS scale for pain. The significance value was sat at p<0.05. To find out the effects of balneotherapy with sulphurous bath on spasticity and pain in affected upper limb. Reduction in tone of affected upper limb muscles was significant in Ex group (p<0.05). Pain decreased significantly in Ex-group (p<0.01). Our results show that balneotherapy with sulphurous water reduces spasticity and pain significantly and can help in treatment of post-stroke patients.
Heiser, Clemens; Fthenakis, Phillippe; Hapfelmeier, Alexander; Berger, Sebastian; Hofauer, Benedikt; Hohenhorst, Winfried; Kochs, Eberhard F; Wagner, Klaus J; Edenharter, Guenther M
2017-09-01
Drug-induced sleep endoscopy (DISE) has become an important diagnostic examination tool in the treatment decision process for surgical therapies in the treatment of obstructive sleep apnea (OSA). Currently, there is a variety of regimes for the performance of DISE, which renders comparison and assessment across results difficult. It remains unclear how the different regimes influence the findings of the examination and the resulting conclusions and treatment recommendations. This study aimed to investigate the correlation between increasing levels of sedation (i.e., light, medium, and deep) induced by propofol using a target-controlled infusion (TCI) pump, with the obstruction patterns at the levels of the velum, oropharynx, tongue base, and epiglottis (i.e., VOTE classification). A second goal was the establishment of a sufficient sedation level to enable a reliable decision regarding treatment recommendations. Forty-three patients with OSA underwent a DISE procedure using propofol TCI. Three levels of sedation were defined, depending on entropy levels and assessment of sedation: light sedation, medium sedation, and deep sedation. The evaluation of the upper airway at each level, with increasing sedation, was documented using the VOTE classification. The elapsed time at which each assessment was performed was recorded. Upper airway changes occurred and were measured throughout the DISE procedure. Clinically useful determinations of airway closure occurred at medium sedation; this level of sedation was most probably achieved with a blood propofol concentration of 3.2 μg/ml. In all 43 patients, definite treatment decisions could be made at medium sedation level. Increasing sedation did not result in changes in the treatment decision. Changes in upper airway collapse during DISE with propofol TCI occur at levels of medium sedation. Decisions regarding surgical treatment could be made at this level of sedation. Upper Airway Collapse in Patients with Obstructive Sleep Apnea Syndrome by Drug Induced Sleep Endoscopy (URL: https://clinicaltrials.gov/ct2/results?term=NCT02588300&Search=Search ) REGISTRATION NUMBER: NCT02588300.
Two different sources of water for the early solar nebula.
Kupper, Stefan; Tornow, Carmen; Gast, Philipp
2012-06-01
Water is essential for life. This is a trivial fact but has profound implications since the forming of life on the early Earth required water. The sources of water and the related amount of delivery depend not only on the conditions on the early Earth itself but also on the evolutionary history of the solar system. Thus we ask where and when water formed in the solar nebula-the precursor of the solar system. In this paper we explore the chemical mechanics for water formation and its expected abundance. This is achieved by studying the parental cloud core of the solar nebula and its gravitational collapse. We have identified two different sources of water for the region of Earth's accretion. The first being the sublimation of the icy mantles of dust grains formed in the parental cloud. The second source is located in the inner region of the collapsing cloud core - the so-called hot corino with a temperature of several hundred Kelvin. There, water is produced efficiently in the gas phase by reactions between neutral molecules. Additionally, we analyse the dependence of the production of water on the initial abundance ratio between carbon and oxygen.
Geology of the Jewel Cave SW Quadrangle, Custer County, South Dakota
Braddock, William A.
1963-01-01
The Jewel Cave SW quadrangle is in the southwestern part of the Black Hills in Custer County, S. Dak., about midway between Edgemont, S. Dak., and Newcastle, Wyo. All the rocks that crop out within the quadrangle are of sedimentary origin and range in age from Pennsylvanian to Early Cretaceous. The Minnesota Formation of Pennsylvania and Permian age, which is about 1,000 feet thick, was studied in outcrop and from two diamond-drill cores. In the subsurface the upper part of the formation consists of gray sandstone, very fine grained dolomite, and anhydrite. The anhydrite has been leached from the formation near the outcrop, perhaps in the early part of the Cenozoic Era, and the resulting subsidence has produced collapse breccias in the Minnelusa and milder deformation in the overlying units. In the collapse breccias the rocks have been oxidized and are red, whereas in the subsurface they are gray. The anhydrite cement of the subsurface sandstone has been replaced by calcite, and the dolomite beds have been partially converted to limestone. The Opeche Formation of Permian age consists of 75 to 115 feet of red siltstone and shale and two thin gypsum beds. The Minnekahta Limestone of Permian age is about 40 feet thick. The Spearfish Formation of Permian and Triassic age is about 550 feet thick and consists of red siltstone red sandstone, dolomite, and gypsum. The dolomite and gypsum beds are restricted to the lower half of the formation. In the northeast corner of the quadrangle the gypsum beds have been dissolved by ground water. The Sundance Formation of Late Jurassic age is divided into five members that have a total thickness of about 360 feet. The Morrison Formation of Late Jurassic age ranges in thickness from 60 to 120 feet. It consists of blocky weathering noncarbonaceous mudstone and subordinate beds of limestone and sandstone. The Inyan Kara Group of Early Cretaceous age has been subdivided into the Lakota Formation and the Fall River Formation. The Lakota Formation consists of 200 to 300 feet of carbonaceous siltstone blocky-weathering claystone, and fine-grained to conglomeratic sandstone. These rocks were deposited in stream channels, flood plains, and ponds. The Fall River Formation is about 110 to 130 feet thick. Along the northeast side of the outcrop the formation consists of fine- to medium-grained sandstone, which forms an elongate body at least 1-1/2 miles wide and more than 25 miles long. To the southwest the formation consists of thinly stratified interbedded sandstone, carbonaceous siltstone, and varicolored mudstone. The Skull Creek and Mowry Shales of Early Cretaceous age consist of black fissile shale. The Mowry contains abundant fish scales and weathers to a silver gray. Alluvium fills the bottom of many intermittent streams, and small gravel-covered terraces mark the former high levels of these streams. Gravel, which caps hills at altitudes of 4,460 to 4,620 feet, is believed to have been deposited by a Pleistocene stream that drained southeastward toward the town of Minnekahta. Many landslides are present along the northward- and eastward-facing scarp of the Inyan Kara hogback. The Dewey fault, trending N. 75 deg E., crosses the quadrangle. It is probably a vertical dip-slip fault, and has an apparent displacement of 250 to 440 feet. Two northwest-trending anticlines are in the quadrangle - one extends from the Edgemont NE quadrangle to near the center of the Jewel Cave SW quadrangle, and the other is limited to the center of the Jewel Cave SW quadrangle. Collapse structures, which were produced by the solution of anhydrite, are (a) breccias in the Minnelusa Formation, (b) limestone-dolomite breccias in the Spearfish Formation, (c) undulations and normal faults in the formations overlying the Minnelusa and (d) breccia pipes that extend upward from the Minnelusa to at least as high as the Lakota Formation. The leaching probably occurred in early Cenozoic time. Minor deformationa
Lekha, Thankappan; Venkatakrishnan, Leelakrishnan; Divya, Karuppannasamy; Lavanya, Perumal
2017-01-01
To report a rare case of periorbital emphysema concurrent with cervicofacial and mediastinal emphysema in an elderly woman who underwent upper gastrointestinal endoscopy for chronic liver disease. An elderly woman with decompensated chronic liver disease presented with features of periorbital, facial, and mediastinal emphysema, characterized with crepitant swelling over the right periorbital area, face, neck, and mediastinum after undergoing upper gastrointestinal endoscopy. There was no history of trauma or Valsalva maneuver. Ocular findings were stable with no evidence of orbital compartmental syndrome. Urgent computed tomography scans of the orbit and chest were performed, and emergency systemic treatment with nasogastric decompression and antibiotics was initiated. However, she suddenly collapsed and succumbed despite all resuscitative efforts. Our case demonstrates that periorbital emphysema can occur following procedures such as upper gastrointestinal endoscopy, in the eyes without history of local trauma. This complication should be suspected especially if there is associated cervicofacial and mediastinal emphysema. Subcutaneous emphysema is usually self-resolving; however, extension of air into deeper planes can cause dangerous complications such as blindness due to orbital emphysema or mortality due to mediastinal emphysema. Hence, prompt diagnosis and urgent intervention are crucial to avoid vision and life threatening complications.
Omnidirectional antenna having constant phase
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sena, Matthew
Various technologies presented herein relate to constructing and/or operating an antenna having an omnidirectional electrical field of constant phase. The antenna comprises an upper plate made up of multiple conductive rings, a lower ground-plane plate, a plurality of grounding posts, a conical feed, and a radio frequency (RF) feed connector. The upper plate has a multi-ring configuration comprising a large outer ring and several smaller rings of equal size located within the outer ring. The large outer ring and the four smaller rings have the same cross-section. The grounding posts ground the upper plate to the lower plate while maintainingmore » a required spacing/parallelism therebetween.« less
Coker-Bolt, Patty; Downey, Ryan J; Connolly, Jacqueline; Hoover, Reagin; Shelton, Daniel; Seo, Na Jin
2017-01-01
The aim of this pilot study was to determine the feasibility and use accelerometers before, during, and after a camp-based constraint-induced movement therapy (CIMT) program for children with hemiplegic cerebral palsy. A pre-test post-test design was used for 12 children with CP (mean = 4.9 yrs) who completed a 30-hour camp-based CIMT program. The accelerometer data were collected using ActiGraph GT9X Link. Children wore accelerometers on both wrists one day before and after the camp and on the affected limb during each camp day. Three developmental assessments were administered pre-post CIMT program. Accelerometers were successfully worn before, during, and directly after the CIMT program to collect upper limb data. Affected upper limb accelerometer activity significantly increased during the CIMT camp compared to baseline (p< 0.05). Significant improvements were seen in all twelve children on all assessments of affected upper limb function (p< 0.05) measuring capacity and quality of affected upper limb functioning. Accelerometers can be worn during high intensity pediatric CIMT programs to collect data about affected upper limb function. Further study is required to determine the relationship between accelerometer data, measure of motor capacity, and real-world performance post-CIMT.
A review of bilateral training for upper extremity hemiparesis.
Stoykov, Mary Ellen; Corcos, Daniel M
2009-01-01
Upper extremity hemiparesis is the most common post-stroke disability. Longitudinal studies have indicated that 30-66% of stroke survivors do not have full arm function 6 months post-stroke. The current gold standard for treatment of mild post-stroke upper limb impairment is constraint-induced therapy but, because of the inclusion criteria, alternative treatments are needed which target more impaired subjects. Bilateral arm training has been investigated as a potential rehabilitation intervention. Bilateral arm training encompasses a number of methods including: (1) bilateral isokinematic training; (2) mirror therapy using bilateral training; (3) device-driven bilateral training; and (4) bilateral motor priming. Neural mechanisms mediating bilateral training are first reviewed. The key bilateral training studies that have demonstrated evidence of efficacy will then be discussed. Finally, conclusions are drawn concerning clinical implications based on the reviewed literature. (c) 2009 John Wiley & Sons, Ltd.
Girometti, R; Brondani, G; Cereser, L; Como, G; Del Pin, M; Bazzocchi, M; Zuiani, C
2010-01-01
Post-cholecystectomy syndrome (PCS) is defined as a complex of heterogeneous symptoms, consisting of upper abdominal pain and dyspepsia, which recur and/or persist after cholecystectomy. Nevertheless, this term is inaccurate, as it encompasses biliary and non-biliary disorders, possibly unrelated to cholecystectomy. Biliary manifestations of PCS may occur early in the post-operative period, usually because of incomplete surgery (retained calculi in the cystic duct remnant or in the common bile duct) or operative complications, such as bile duct injury and/or bile leakage. A later onset is commonly caused by inflammatory scarring strictures involving the sphincter of Oddi or the common bile duct, recurrent calculi or biliary dyskinesia. The traditional imaging approach for PCS has involved ultrasound and/or CT followed by direct cholangiography, whereas manometry of the sphincter of Oddi and biliary scintigraphy have been reserved for cases of biliary dyskinesia. Because of its capability to provide non-invasive high-quality visualisation of the biliary tract, magnetic resonance cholangiopancreatography (MRCP) has been advocated as a reliable imaging tool for assessing patients with suspected PCS and for guiding management decisions. This paper illustrates the rationale for using MRCP, together with the main MRCP biliary findings and diagnostic pitfalls. PMID:20335441
Sahara, Noriyuki; Moriyama, Keita; Iida, Midori; Watanabe, Shun
2016-06-01
The present study was aimed at elucidating the time and order of eruption of first functional teeth in the upper jaw of post-larval life of Sicyopterus japonicus (S. japonicus) during cranial metamorphosis at the time of river recruitment. Fishes were caught at the post-larval stage at a river mouth and maintained for 7 days in a water tank. Each of 10 specimens was evaluated every day for 7 days by using microcomputed tomography, scanning electron microscopy, and light microscopy with peculiar attention to the development of the upper jaw teeth. Fishes caught at the river mouth were mostly transparent, with a rostral terminal mouth, and no teeth could be found in either the upper or lower jaw. At 2 days after collection, the mouth position changed from terminal to subterminal, resulting from a change in head shape. The initial eruption of first functional teeth was detected at the anterior two-thirds region of each upper jaw. These teeth erupted in adjacent positions, most had a tricuspid crown, and they represented miniature versions of adult teeth. At 5 days, the position of the mouth became further relocated from terminal rostral to ventral. The number of erupted teeth increased, followed by spreading of them anteriorly and posteriorly. At 7 days, they formed a single row of close-set tricuspid teeth along the entire length of each upper jaw. The present study demonstrated that even under laboratory conditions a rapid and drastic cranial metamorphosis took place within a week after the time of collection of post-larval S. japonicus from a river. The eruption of first functional teeth in the upper jaw of S. japonicus, which teeth are adapted to scraping algae off the substrate, was initially detected at 2 days after collection, and first functional dentition of the upper jaw was set up within 7 days after it. Copyright © 2016 Elsevier Ltd. All rights reserved.
Pierson, Tom C.; Scott, William E.; Vallance, James W.; Pringle, Patrick T.; O'Connor, Jim; Dorsey, Rebecca; Madin, Ian
2009-01-01
Late Holocene dome-building eruptions at Mount Hood during the Timberline and Old Maid eruptive periods resulted in numerous dome-collapse pyroclastic flows and lahars that moved large volumes of volcaniclastic sediment into temporary storage in headwater canyons of the Sandy River. During each eruptive period, accelerated sediment loading to the river through erosion and remobilization of volcanic fragmental debris resulted in very high sediment-transport rates in the Sandy River during rain- and snowmelt-induced floods. Large sediment loads in excess of the river's transport capacity led to channel aggradation, channel widening, and change to a braided channel form in the lowermost reach of the river, between 61 and 87 km downstream from the volcano. The post-eruption sediment load moved as a broad bed-material wave, which in the case of the Old Maid eruption took ~2 decades to crest 83 km downstream. Maximum post-eruption aggradation levels of at least 28 and 23 m were achieved in response to Timberline and Old Maid eruptions. In each case, downstream aggradation cycles were initiated by lahars, but the bulk of the aggradation was achieved by fluvial sediment transport and deposition. When the high rates of sediment supply began to diminish, the river degraded, incising the channel fills and forming progressively lower sets of degradational terraces. A variety of debris-flow, hyperconcentrated-flow, and fluvial (upper and lower flow regime) deposits record the downstream passage of the sediment waves that were initiated by these eruptions. The deposits also presage a hazard that may be faced by communities along the Sandy River when volcanic activity at Mount Hood resumes.
NASA Astrophysics Data System (ADS)
Feucht, D. W.; Bedrosian, P.; Jiracek, G. R.; Pellerin, L.; Nettleton, C. E.
2017-12-01
The Valles caldera, in north-central New Mexico, USA, is a 20-km wide topographic depression in the Jemez Mountains volcanic complex that formed during two massive ignimbrite eruptions 1.65 and 1.26 Ma. Post-collapse volcanic activity in the caldera includes the rise of a 1 km high resurgent dome, periodic eruptions of the Valles rhyolite along ring fractures, and the presence of a geothermal reservoir beneath the western caldera with temperatures in excess of 300°C at a mere 2 km depth. We present an electrical resistivity model of the upper crust from three-dimensional (3D) inversion of broadband (100 Hz to 600 s) magnetotelluric (MT) data collected in and around the Valles caldera. The Summer of Applied Geophysical Experience (SAGE) has been acquiring geophysical data in the northern Rio Grande rift for more than three decades (1983-2017). Included in that vast dataset are over 60 broadband magnetotelluric soundings that have recently been cataloged, geo-located, and digitized for use in modern geophysical processing and modeling. The resistivity models presented here were produced by inverting a subset of SAGE MT data along with 30 broadband MT soundings acquired by the Unocal Corporation in 1983 for geothermal exploration of the caldera. We use the 3D inversion algorithm ModEM (Egbert and Kelbert, 2012) to invert full impedance tensors and tipper functions from >30 MT stations for the electrical resistivity structure beneath the caldera. Our preferred model reveals the geometry and electrical properties of (1) the conductive caldera fill, (2) the resistive crystalline basement, and (3) an enigmatic mid-crustal conductor related to magmatic activity that post-dates caldera formation.
Brittle and Ductile Behavior in Deep-Seated Landslides: Learning from the Vajont Experience
NASA Astrophysics Data System (ADS)
Paronuzzi, Paolo; Bolla, Alberto; Rigo, Elia
2016-06-01
This paper analyzes the mechanical behavior of the unstable Mt. Toc slope before the 1963 catastrophic collapse, considering both the measured data (surface displacements and microseismicity) and the updated geological model of the prehistoric rockslide. From February 1960 up to 9 October 1963, the unstable mass behaved as a brittle-ductile `mechanical system,' characterized by remarkable microseismicity as well as by considerable surface displacements (up to 4-5 m). Recorded microshocks were the result of progressive rock fracturing of distinct resisting stiff parts made up of intact rock (indentations, undulations, and rock bridges). The main resisting stiff part was a large rock indentation located at the NE extremity of the unstable mass that acted as a mechanical constraint during the whole 1960-1963 period, inducing a progressive rototranslation toward the NE. This large constraint failed in autumn 1960, when an overall slope failure took place, as emphasized by the occurrence of the large perimetrical crack in the upper slope. In this circumstance, the collapse was inhibited by a reblocking phenomenon of the unstable mass that had been previously destabilized by the first reservoir filling. Progressive failure of localized intact rock parts progressively propagated westwards as a consequence of the two further filling-drawdown cycles of the reservoir (1962 and 1963). The characteristic brittle-ductile behavior of the Vajont landslide was made possible by the presence of a very thick (40-50 m) and highly deformable shear zone underlying the upper rigid rock mass (100-120 m thick).
Sleep-Disordered Breathing in Neuromuscular Disease: Diagnostic and Therapeutic Challenges.
Aboussouan, Loutfi S; Mireles-Cabodevila, Eduardo
2017-10-01
Normal sleep-related rapid eye movement sleep atonia, reduced lung volumes, reduced chemosensitivity, and impaired airway dilator activity become significant vulnerabilities in the setting of neuromuscular disease. In that context, the compounding effects of respiratory muscle weakness and disease-specific features that promote upper airway collapse or cause dilated cardiomyopathy contribute to various sleep-disordered breathing events. The reduction in lung volumes with neuromuscular disease is further compromised by sleep and the supine position, exaggerating the tendency for upper airway collapse and desaturation with sleep-disordered breathing events. The most commonly identified events are diaphragmatic/pseudo-central, due to a decrease in the rib cage contribution to the tidal volume during phasic rapid eye movement sleep. Obstructive and central sleep apneas are also common. Noninvasive ventilation can improve survival and quality of sleep but should be used with caution in the context of dilated cardiomyopathy or significant bulbar symptoms. Noninvasive ventilation can also trigger sleep-disordered breathing events, including ineffective triggering, autotriggering, central sleep apnea, and glottic closure, which compromise the potential benefits of the intervention by increasing arousals, reducing adherence, and impairing sleep architecture. Polysomnography plays an important diagnostic and therapeutic role by correctly categorizing sleep-disordered events, identifying sleep-disordered breathing triggered by noninvasive ventilation, and improving noninvasive ventilation settings. Optimal management may require dedicated hypoventilation protocols and a technical staff well versed in the identification and troubleshooting of respiratory events. Copyright © 2017 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
Newhall, C.G.; Bronto, S.; Alloway, B.; Banks, N.G.; Bahar, I.; Del Marmol, M.A.; Hadisantono, R.D.; Holcomb, R.T.; McGeehin, J.; Miksic, J.N.; Rubin, M.; Sayudi, S.D.; Sukhyar, R.; Andreastuti, Supriyati; Tilling, R.I.; Torley, R.; Trimble, D.; Wirakusumah, A.D.
2000-01-01
Stratigraphy and radiocarbon dating of pyroclastic deposits at Merapi Volcano, Central Java, reveals ~10,000 years of explosive eruptions. Highlights include: (1) Construction of an Old Merapi stratovolcano to the height of the present cone or slightly higher. Our oldest age for an explosive eruption is 9630±60 14C y B.P.; construction of Old Merapi certainly began earlier. (2) Collapse(s) of Old Merapi that left a somma rim high on its eastern slope and sent one or more debris avalanche(s) down its southern and western flanks. Impoundment of Kali Progo to form an early Lake Borobudur at ~3400 14C y B.P. hints at a possible early collapse of Merapi. The latest somma-forming collapse occurred ~1900 14C y B.P. The current cone, New Merapi, began to grow soon thereafter. (3) Several large and many small Buddhist and Hindu temples were constructed in Central Java between 732 and ~900 A.D. (roughly, 1400-1000 14C y B.P.). Explosive Merapi eruptions occurred before, during and after temple construction. Some temples were destroyed and (or) buried soon after their construction, and we suspect that this destruction contributed to an abrupt shift of power and organized society to East Java in 928 A.D. Other temples sites, though, were occupied by "caretakers" for several centuries longer. (4) A partial collapse of New Merapi occurred 14C y B.P. Eruptions ~700-800 14C y B.P. (12-14th century A.D.) deposited ash on the floors of (still-occupied?) Candi Sambisari and Candi Kedulan. We speculate but cannot prove that these eruptions were triggered by (the same?) partial collapse of New Merapi, and that the eruptions, in turn, ended "caretaker" occupation at Candi Sambisari and Candi Kedulan. A new or raised Lake Borobudur also existed during part or all of the 12-14th centuries, probably impounded by deposits from Merapi. (5) Relatively benign lava-dome extrusion and dome-collapse pyroclastic flows have dominated activity of the 20th century, but explosive eruptions much larger than any of this century have occurred many times during Merapi's history, most recently during the 19th century. Are the relatively small eruptions of the 20th century a new style of open-vent, less hazardous activity that will persist for the foreseeable future? Or, alternatively, are they merely low-level "background" activity that could be interrupted upon relatively short notice by much larger explosive eruptions? The geologic record suggests the latter, which would place several hundred thousand people at risk. We know of no reliable method to forecast when an explosive eruption will interrupt the present interval of low-level activity. This conclusion has important implications for hazard evaluation.
Petroleum systems of the Southeast Tertiary basins and Marbella area, Southeast Mexico
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fuentes, F.
1996-08-01
This study was done in an area where insufficient organic-rich rocks were available for a reliable oil-source rock correlation. However, oil-rock correlations, molecular characteristics of key horizons, paleofacies maps, maturation and potential migration pathways suggest the Tithonian as a major source rock. Moreover, there is good evidence of high quality source rocks in Oxfordian, Kimmeridgian, Middle-Upper Cretaceous and Paleogene (mainly in the Eocene). Plays were identified in Upper Jurassic oolitic sequences, Early-Middle Cretaceus carbonate platform rocks and breccias, Late Cretaceous basinal fracture carbonates, Paleogene carbonates and breccias, Early-Middle Miocene mounds and submarine fans and isolated carbonate platform sediments and Miocene-Recentmore » turbidites. Seal rocks are shaly carbonates and anhydrites from Tithonian, basinal carbonates and anhydrites from Middle-Upper Cretaceous, basinal carbonates and marls from Upper Cretaceous and Paleogene shales, and bathyal shales from Early Miocene-Recent. The first phase of oil migration from upper Jurassic-Early Cretaceous source rocks occurred in the Early-Middle Cretaceous. In the Upper Cretaceous the Chortis block collided with Chiapas, and as a result mild folding and some hydrocarbons were emplaced to the structural highs. The main phase of structuration and folding of the Sierra de Chiapas started in the Miocene, resulting in well-defined structural traps. Finally, in Plio-Pleistocene the Chortis block was separated, the major compressional period finished and the southern portion of Sierra de Chiapas was raised isostatically. As a result of major subsidence, salt withdrawal and increased burial depth, conditions were created for the generation of liquid hydrocarbons from the Paleogene shales.« less
Tammaro, Leonardo; Buda, Andrea; Di Paolo, Maria Carla; Zullo, Angelo; Hassan, Cesare; Riccio, Elisabetta; Vassallo, Roberto; Caserta, Luigi; Anderloni, Andrea; Natali, Alessandro
2014-09-01
Pre-endoscopic triage of patients who require an early upper endoscopy can improve management of patients with non-variceal upper gastrointestinal bleeding. To validate a new simplified clinical score (T-score) to assess the need of an early upper endoscopy in non variceal bleeding patients. Secondary outcomes were re-bleeding rate, 30-day bleeding-related mortality. In this prospective, multicentre study patients with bleeding who underwent upper endoscopy were enrolled. The accuracy for high risk endoscopic stigmata of the T-score was compared with that of the Glasgow Blatchford risk score. Overall, 602 patients underwent early upper endoscopy, and 472 presented with non-variceal bleeding. High risk endoscopic stigmata were detected in 145 (30.7%) cases. T-score sensitivity and specificity for high risk endoscopic stigmata and bleeding-related mortality was 96% and 30%, and 80% and 71%, respectively. No statistically difference in predicting high risk endoscopic stigmata between T-score and Glasgow Blatchford risk score was observed (ROC curve: 0.72 vs. 0.69, p=0.11). The two scores were also similar in predicting re-bleeding (ROC curve: 0.64 vs. 0.63, p=0.4) and 30-day bleeding-related mortality (ROC curve: 0.78 vs. 0.76, p=0.3). The T-score appeared to predict high risk endoscopic stigmata, re-bleeding and mortality with similar accuracy to Glasgow Blatchford risk score. Such a score may be helpful for the prediction of high-risk patients who need a very early therapeutic endoscopy. Copyright © 2014 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Lou, Yu-Qing; Xia, Yu-Kai
2017-05-01
We study magnetohydrodynamic (MHD) self-similar collapses and void evolution, with or without shocks, of a general polytropic quasi-spherical magnetofluid permeated by random transverse magnetic fields under the Paczynski-Wiita gravity that captures essential general relativistic effects of a Schwarzschild black hole (BH) with a growing mass. Based on the derived set of non-linear MHD ordinary differential equations, we obtain various asymptotic MHD solutions, the geometric and analytical properties of the magnetosonic critical curve (MSCC) and MHD shock jump conditions. Novel asymptotic MHD solution behaviours near the rim of central expanding voids are derived analytically. By exploring numerical global MHD solutions, we identify allowable boundary conditions at large radii that accommodate a smooth solution and show that a reasonable amount of magnetization significantly increases the mass accretion rate in the expansion-wave-collapse solution scenario. We also construct the counterparts of envelope-expansion-core-collapse solutions that cross the MSCC twice, which are found to be closely paired with a sequence of global smooth solutions satisfying a novel type of central MHD behaviours. MHD shocks with static outer and various inner flow profiles are also examined. Astrophysical applications include dynamic core collapses of magnetized massive stars and compact objects as well as formation of supermassive, hypermassive, dark matter and mixed matter BHs in the Universe, including the early Universe. Such gigantic BHs can be detected in X-ray/gamma-ray sources, quasars, ultraluminous infrared galaxies or extremely luminous infrared galaxies and dark matter overwhelmingly dominated elliptical galaxies as well as massive dark matter halos, etc. Gravitational waves and electromagnetic wave emissions in broad band (including e.g., gamma-ray bursts and fast radio bursts) can result from this type of dynamic collapses of forming BHs involving magnetized media.
CONTRACTION SIGNATURES TOWARD DENSE CORES IN THE PERSEUS MOLECULAR CLOUD
DOE Office of Scientific and Technical Information (OSTI.GOV)
Campbell, J. L.; Friesen, R. K.; Martin, P. G.
We report the results of an HCO{sup +} (3–2) and N{sub 2}D{sup +} (3–2) molecular line survey performed toward 91 dense cores in the Perseus molecular cloud using the James Clerk Maxwell Telescope, to identify the fraction of starless and protostellar cores with systematic radial motions. We quantify the HCO{sup +} asymmetry using a dimensionless asymmetry parameter δ{sub v}, and identify 20 cores with significant blue or red line asymmetries in optically thick emission indicative of collapsing or expanding motions, respectively. We separately fit the HCO{sup +} profiles with an analytic collapse model and determine contraction (expansion) speeds toward 22more » cores. Comparing the δ{sub v} and collapse model results, we find that δ{sub v} is a good tracer of core contraction if the optically thin emission is aligned with the model-derived systemic velocity. The contraction speeds range from subsonic (0.03 km s{sup −1}) to supersonic (0.4 km s{sup −1}), where the supersonic contraction speeds may trace global rather than local core contraction. Most cores have contraction speeds significantly less than their free-fall speeds. Only 7 of 28 starless cores have spectra well-fit by the collapse model, which more than doubles (15 of 28) for protostellar cores. Starless cores with masses greater than the Jeans mass (M/M{sub J} > 1) are somewhat more likely to show contraction motions. We find no trend of optically thin non-thermal line width with M/M{sub J}, suggesting that any undetected contraction motions are small and subsonic. Most starless cores in Perseus are either not in a state of collapse or expansion, or are in a very early stage of collapse.« less
3. EAST FACADE OF THE UPPER FALLS GATE HOUSE, FOREBAY ...
3. EAST FACADE OF THE UPPER FALLS GATE HOUSE, FOREBAY IN LEFT FOREGROUND, SPOKANE CITY HALL IN LEFT BACKGROUND, LOOKING WEST. - Washington Water Power Spokane River Upper Falls Hydroelectric Development, Gate House, Spokane River, approximately 0.5 mile northeast of intersection of Spokane Falls Boulevard & Post Street, Spokane, Spokane County, WA
Privatisation of Public Education? The Emergence of Independent Upper Secondary Schools in Sweden
ERIC Educational Resources Information Center
Arreman, Inger Erixon; Holm, Ann-Sofie
2011-01-01
This article explores the upper secondary (or post-16) school market. The study on which it is based, funded by the Swedish Research Council, was entitled "Upper-secondary education as a market". Empirical data include official statistics, policy documents, school publications, company reports and school visits. Printed and other news…