Zhang, Ben; Jia, Wei-Hua; Matsuo, Keitaro; Shin, Aesun; Xiang, Yong-Bing; Matsuda, Koichi; Jee, Sun Ha; Kim, Dong-Hyun; Cheah, Peh Yean; Ren, Zefang; Cai, Qiuyin; Long, Jirong; Shi, Jiajun; Wen, Wanqing; Yang, Gong; Ji, Bu-Tian; Pan, Zhi-Zhong; Matsuda, Fumihiko; Gao, Yu-Tang; Oh, Jae Hwan; Ahn, Yoon-Ok; Kubo, Michiaki; Thean, Lai Fun; Park, Eun Jung; Li, Hong-Lan; Park, Ji Won; Jo, Jaeseong; Jeong, Jin-Young; Hosono, Satoyo; Nakamura, Yusuke; Shu, Xiao-Ou; Zeng, Yi-Xin; Zheng, Wei
Genome-wide association studies (GWAS) of colorectal cancer (CRC) have been conducted primarily in European descendants. In a GWAS conducted in East Asians, we first analyzed approximately 1.7 million single-nucleotide polymorphisms (SNPs) in four studies with 1,773 CRC cases and 2,642 controls. We then selected 66 promising SNPs for replication and genotyped them in three independent studies with 3,612 cases and 3,523 controls. Five SNPs were further evaluated using data from four additional studies including up to 3,290 cases and 4,339 controls. SNP rs7229639 in the SMAD7 gene was found to be associated with CRC risk with an odds ratio (95% confidence interval) associated with the minor allele (A) of 1.22 (1.15-1.29) in the combined analysis of all 11 studies (p = 2.93 × 10(-11) ). SNP rs7229639 is 2,487 bp upstream from rs4939827, a risk variant identified previously in a European-ancestry GWAS in relation to CRC risk. However, these two SNPs are not correlated in East Asians (r(2) = 0.008) nor in Europeans (r(2) = 0.146). The CRC association with rs7229639 remained statistically significant after adjusting for rs4939827 as well as three additional CRC risk variants (rs58920878, rs12953717 and rs4464148) reported previously in this region. SNPs rs7229639 and rs4939827 explained approximately 1% of the familial relative risk of CRC in East Asians. This study identifies a new CRC risk variant in the SMAD7 gene, further highlighting the significant role of this gene in the etiology of CRC.
Hwang, Joo-Yeon; Sim, Xueling; Wu, Ying; Liang, Jun; Tabara, Yasuharu; Hu, Cheng; Hara, Kazuo; Tam, Claudia H T; Cai, Qiuyin; Zhao, Qi; Jee, Sunha; Takeuchi, Fumihiko; Go, Min Jin; Ong, Rick Twee Hee; Ohkubo, Takayoshi; Kim, Young Jin; Zhang, Rong; Yamauchi, Toshimasa; So, Wing Yee; Long, Jirong; Gu, Dongfeng; Lee, Nanette R; Kim, Soriul; Katsuya, Tomohiro; Oh, Ji Hee; Liu, Jianjun; Umemura, Satoshi; Kim, Yeon-Jung; Jiang, Feng; Maeda, Shiro; Chan, Juliana C N; Lu, Wei; Hixson, James E; Adair, Linda S; Jung, Keum Ji; Nabika, Toru; Bae, Jae-Bum; Lee, Mi Hee; Seielstad, Mark; Young, Terri L; Teo, Yik Ying; Kita, Yoshikuni; Takashima, Naoyuki; Osawa, Haruhiko; Lee, So-Hyun; Shin, Min-Ho; Shin, Dong Hoon; Choi, Bo Youl; Shi, Jiajun; Gao, Yu-Tang; Xiang, Yong-Bing; Zheng, Wei; Kato, Norihiro; Yoon, Miwuk; He, Jiang; Shu, Xiao Ou; Ma, Ronald C W; Kadowaki, Takashi; Jia, Weiping; Miki, Tetsuro; Qi, Lu; Tai, E Shyong; Mohlke, Karen L; Han, Bok-Ghee; Cho, Yoon Shin; Kim, Bong-Jo
Fasting plasma glucose (FPG) has been recognized as an important indicator for the overall glycemic state preceding the onset of metabolic diseases. So far, most indentified genome-wide association loci for FPG were derived from populations with European ancestry, with a few exceptions. To extend a thorough catalog for FPG loci, we conducted meta-analyses of 13 genome-wide association studies in up to 24,740 nondiabetic subjects with East Asian ancestry. Follow-up replication analyses in up to an additional 21,345 participants identified three new FPG loci reaching genome-wide significance in or near PDK1-RAPGEF4, KANK1, and IGF1R. Our results could provide additional insight into the genetic variation implicated in fasting glucose regulation.
Chen, C; Zhang, X
Endoplasmic reticulum aminopeptidase 1 (ERAP1) has been confirmed to be associated with ankylosing spondylitis (AS) in Caucasian. However, whether they are associated with AS in East Asian population remains unidentified. We investigated this relationship by a new Chinese case-control study and a meta-analysis of published series. 368 cases and 460 controls were recruited in the Chinese case-control study. Genotyping was completed using the chip-based matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Allelic associations were analysed using contingency tables. In the meta-analysis, up to 2748 cases and 2774 controls from seven different studies and the new Chinese study were combined using Review Manager software version 5.1.1. Mantel-Haenszel or Inverse Variance test was used to calculate fixed or random-effects pooled ORs. In the new Chinese study, strong association with AS was observed for marker rs10050860, rs27434 and rs1065407 at P value of <0.001. Moderate association was observed for rs30187 at P value of <0.01, while no association was observed for rs27044 (P = 0.37) and rs2287987 (P = 0.23). The meta-analysis showed that rs27037 and rs30187 were strongly associated with AS (P < 0.00001). Significant association was also observed for rs27434 (P = 0.001). No association was shown for rs27044 (P = 0.70). We concluded that ERAP1 variants are associated with AS in East Asian population, indicating a common pathogenic mechanism for AS in East Asians and Caucasians.
Chen, Yi-An; Hsu, Chao-Kai; Lee, Julia Yu-Yun; Yang, Chao-Chun
A 32-year-old Taiwanese man presented to our clinic with a 6-month history of linear hair loss in a wavy and curved pattern across the parietal and occipital scalp, resembling the distribution of Blaschko's lines. Physical examination showed interfollicular erythema and follicular plugging without skin atrophy or sclerotic change. Histopathology revealed a lymphoplasmacytic infiltrate in the perifollicular dermis and subcutis with abundant mucin deposition, consistent with the diagnosis of lupus panniculitis. Treatment with hydroxychloroquine and local steroid injection resulted in complete hair regrowth but recurrence was noted. Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines had so far been reported exclusively in five East Asians. Apart from classical lupus panniculitis, it had distinct clinical and histopathological features such as younger age of onset, male predominance, reversible clinical course without scarring, fewer associations with systemic lupus erythematosus, exclusive involvement of scalp, sparse inflammatory infiltration, abundant mucin deposition, higher degree of hyaline fat degeneration and negative results of immunofluorescent studies. Therefore, we propose linear lupus panniculitis of the scalp to be a distinct variant of lupus panniculitis and should be included in the differential diagnosis for focal or linear alopecia, especially in East Asians.
Waki, A; Sasazaki, S; Kobayashi, E; Mannen, H
This study was a first analysis of paternal genetic diversity for extensive Asian domestic goats using SRY gene sequences. Sequencing comparison of the SRY 3'-untranslated region among 210 Asian goats revealed four haplotypes (Y1A, Y1B, Y2A and Y2B) derived from four variable sites including a novel substitution detected in this study. In Asian goats, the predominant haplotype was Y1A (62%) and second most common was Y2B (30%). Interestingly, the Y2B was a unique East Asian Y chromosomal variant, which differentiates eastern and western Eurasian goats. The SRY geographic distribution in Myanmar and Cambodia indicated predominant the haplotype Y1A in plains areas and a high frequency of Y2B in mountain areas. The results suggest recent genetic infiltration of modern breeds into South-East Asian goats and an ancestral SRY Y2B haplotype in Asian native goats.
This study has investigated the relation between the East Asian monsoon and the South Asian monsoon at intraseasonal time scale during the boreal summer. Applying a data adaptive method on daily anomalies of precipitation, two leading intraseasonal oscillations (ISOs) were extracted separately in the regions of South Asia, tropical East Asia and subtropical East Asia. The first ISO has a period of about 45 days and propagates northward and eastward over the South Asian and tropical East Asian regions. The second ISO, with a period of about 26 days, propagates northeastward over South Asia and northwestward over tropical East Asia. Although both the ISOs are also present over the subtropical East Asia, the variance is low while no propagation is evident. The circulation patterns associated with the ISOs were found to be consistent with the corresponding precipitation patterns of the ISOs. The two ISOs also reveal consistency with the space-time evolution of diabatic heating, convection, vertical motion, upper-level divergence and moisture transport. The zonal and meridional propagation of the ISOs provide a strong link between the South Asian monsoon and East Asian monsoon regions. The subtropical East Asian region seems to have a weaker link with the other monsoon regions.
Chao, Roger Y., Jr.
The Author argues that historical regional developments in Europe and East Asia greatly influence the formation of an East Asian Higher Education Area. As such, this article compares European and East Asian regionalization and higher education regionalization processes to show this path dependency in East Asian regionalization of higher education…
A reading-writing initiative began in 2011-12 at the University of Toronto as a partnership between an East Asian Studies (EAS) department and an English Language Learning (ELL) Program. In this institution, students are expected to enter into scholarly discussions in their first year essays, yet many (both native English speakers and non-native…
Fernandez, L R
Creation of a dynamic levator aponeurosis fold or double eye adds to the beauty of the East Asian. The eyes are larger and less puffy, and the eyelashes appear longer and curve up and out instead of down. The distance from the ciliary border to the eyebrow is decreased and more in proportion. The Mongolian trait is preserved.
Wang, Qiuyan; Wang, Zhili; Zhang, Hua
The impact of the total effects due to anthropogenic aerosols from global, East Asian, and non-East Asian sources on East Asian summer monsoon (EASM) system is studied using an aerosol-climate online model BCC_AGCM2.0.1_CUACE/Aero. The results show that the summer mean net all-sky shortwave fluxes averaged over East Asian monsoon region (EAMR) at the top of the atmosphere (TOA) and surface reduce by 4.8 and 5.0 W m- 2, respectively, due to the increases of global aerosol emissions in 2000 relative to 1850. Changes in radiations and their resulting changes in heat and water transport and cloud fraction contribute together to the surface cooling over EAMR in summer. The increases in global anthropogenic aerosols lead to a decrease of 2.1 K in summer mean surface temperature and an increase of 0.4 hPa in summer mean surface pressure averaged over EAMR, respectively. It is shown that the changes in surface temperature and pressure are significantly larger over land than ocean, thus decreasing the contrast of land-sea surface temperature and pressure. This results in the marked anomalies of north and northeast winds over eastern and southern China and the surrounding oceans in summer, thereby weakening the EASM. The summer mean precipitation averaged over the EAMR reduces by 12%. The changes in non-East Asian aerosol emissions play a more important role in inducing the changes of local temperature and pressure, and thus significantly exacerbate the weakness of the EASM circulation due to local aerosol changes. The weakening of circulation due to both is comparable, and even the effect of non-local aerosols is larger in individual regions. The changes of local and non-local aerosols contribute comparably to the reductions in precipitation over oceans, whereas cause opposite changes over eastern China. Our results highlight the importance of aerosol changes outside East Asia in the impact of the changes of anthropogenic aerosols on EASM.
Marques, Patrícia Isabel; Fonseca, Filipa; Sousa, Tânia; Santos, Paulo; Camilo, Vânia; Ferreira, Zélia; Quesada, Victor; Seixas, Susana
The human kallikrein (KLK) cluster, located at chromosome 19q13.3-13.4, encodes 15 serine proteases, including neighboring genes (KLK3, KLK2, KLK4, and KLK5) with key roles in the cascades of semen liquefaction, tooth enamel maturation, and skin desquamation. KLK2 and KLK3 were previously identified as targets of adaptive evolution in primates through different mechanisms linked to reproductive biology and, in humans, genome-wide scans of positive selection captured, a yet unexplored, evidence for KLK neutrality departure in East Asians. We perform a detailed evaluation of KLK3-KLK5 variability in the 1000 Genomes samples from East Asia, Europe, and Africa, which was sustained by our own sequencing. In East Asians, we singled out a 70-kb region surrounding KLK4 that combined unusual low levels of diversity, high frequency variants with significant levels of population differentiation (FST > 0.5) and fairly homogenous haplotypes given the large local recombination rates. Among these variants, rs1654556_G, rs198968_T, and rs17800874_A stand out for their location on putative regulatory regions and predicted functional effects, namely the introduction of several microRNA binding sites and a repressor motif. Our functional assays carried out in different cellular models showed that rs198968_T and rs17800874_A operate synergistically to reduce KLK4 expression and could be further assisted by rs1654556_G. Considering the previous findings that KLK4 inactivation causes enamel malformations in humans and mice, and that this gene is coexpressed in epidermal layers along with several substrates involved in either cell adhesion or keratinocyte differentiation, we propose KLK4 as another target of selection in East Asians correlated to tooth and epidermal morphological traits.
Gross, Eric R.; Zambelli, Vanessa O.; Small, Bryce A.; Ferreira, Julio C.B.; Chen, Che-Hong; Mochly-Rosen, Daria
Asian Americans are one of the fastest-growing populations in the United States. A relatively large subset of this population carries a unique loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2. Found in approximately 560 million people of East Asian descent, ALDH2*2 reduces enzymatic activity by approximately 60% to 80% in heterozygotes. Furthermore, this variant is associated with a higher risk for several diseases affecting many organ systems, including a particularly high incidence relative to the general population of esophageal cancer, myocardial infarction, and osteoporosis. In this review, we discuss the pathophysiology associated with the ALDH2*2 variant, describe why this variant needs to be considered when selecting drug treatments, and suggest a personalized medicine approach for Asian American carriers of this variant. We also discuss future clinical and translational perspectives regarding ALDH2*2 research. PMID:25292432
The Indian and East Asian summer monsoons are two components of the whole Asian summer monsoon system. Previous studies have indicated in-phase and out-of-phase variations between Indian and East Asian summer rainfall. The present study reviews the current understanding of the connection between Indian and East Asian summer rainfall. The review covers the relationship of northern China, southern Japan, and South Korean summer rainfall with Indian summer rainfall; the atmospheric circulation anomalies connecting Indian and East Asian summer rainfall variations; the long-term change in the connection between Indian and northern China rainfall and the plausible reasons for the change; and the influence of ENSO on the relationship between Indian and East Asian summer rainfall and its change. While much progress has been made about the relationship between Indian and East Asian summer rainfall variations, there are several remaining issues that need investigation. These include the processes involved in the connection between Indian and East Asian summer rainfall, the non-stationarity of the connection and the plausible reasons, the influences of ENSO on the relationship, the performance of climate models in simulating the relationship between Indian and East Asian summer rainfall, and the relationship between Indian and East Asian rainfall intraseasonal fluctuations.
Wajima, K.; Hagiwara, Y.; An, T.; Baan, W. A.; Fujisawa, K.; Hao, L.; Jiang, W.; Jung, T.; Kawaguchi, N.; Kim, J.; Kobayashi, H.; Oh, S.-J.; Roh, D.-G.; Wang, M. Wu, Y.; Xia, B.; Zhang, M.
The East-Asian VLBI Network (EAVN) is the international VLBI facility in East Asia and is conducted in collaboration with China, Japan, and Korea. The EAVN consists of VLBI arrays operated in each East Asian country, containing 21 radio telescopes and three correlators. The EAVN will be mainly operated at 6.7 (C-band), 8 (X-band), 22 (K-band), and 43 GHz (Q-band), although the EAVN has an ability to conduct observations at 1.6 - 129 GHz. We have conducted fringe test observations eight times to date at 8 and 22 GHz and fringes have been successfully detected at both frequencies. We have also conducted science commissioning observations of 6.7 GHz methanol masers in massive star-forming regions. The EAVN will be operational from the second half of 2017, providing complementary results with the FAST on AGNs, massive star-forming regions, and evolved stars with high angular resolution at cm- to mm-wavelengths.
Park, Joon Oh; Ryoo, Baek-Yeol; Yen, Chia-Jui; Kudo, Masatoshi; Yang, Ling; Abada, Paolo B.; Cheng, Rebecca; Orlando, Mauro; Zhu, Andrew X.; Okusaka, Takuji
Purpose REACH investigated second-line ramucirumab therapy for advanced hepatocellular carcinoma. Results Median overall survival was 8.2 months for ramucirumab and 6.9 months for placebo (HR, 0.835; 95% CI, 0.634–1.100; p = 0.2046) for East Asians, and 10.1 months for ramucirumab and 8.0 months for placebo (HR, 0.895; 95% CI, 0.690–1.161; p = 0.4023) for non-East Asians. Median overall survival in patients with baseline alpha-fetoprotein ≥ 400 ng/mL was 7.8 months for ramucirumab and 4.2 months for placebo (HR, 0.749; 95% CI, 0.519–1.082; p = 0.1213) for East Asians (n = 139), and 8.2 months for ramucirumab and 4.5 months for placebo (HR, 0.579; 95% CI, 0.371–0.904; p = 0.0149) for non-East Asians (n = 111). The most common grade ≥ 3 treatment-emergent adverse events in East Asians and non-East Asians included hypertension and malignant neoplasm progression. Materials and methods A post-hoc analysis of East Asians (N = 252) and non-East Asians (N = 313) in the intent-to-treat population was performed. Conclusions In East Asians and non-East Asians, ramucirumab did not significantly prolong overall survival. In patients with baseline alpha-fetoprotein ≥ 400 ng/mL, a potentially larger survival benefit was observed in both subgroups. Safety for East Asians was similar to non-East Asians. PMID:27776351
Kazennova, Elena; Laga, Vita; Lapovok, Ilya; Glushchenko, Nataliya; Neshumaev, Dmitry; Vasilyev, Alexander
Abstract A molecular analysis of HIV-1 subtypes and recombinants circulating in cities in the Russian Far East was performed. The study included samples from 201 outpatients from Vladivostok, Khabarovsk, and Blagoveshchensk. In most parts of Russia, patients are infected with HIV-1 subtype A, known as the IDU-A variant. Subtype B, including the IDU-B variant, is rare in Russia but widespread in the Ukraine, and the CRF02_AG is prevalent in Central Asian countries and Siberia, Russia. One of the challenges of this study in the Far East was to determine whether the molecular landscape of HIV infection in this region is influenced by the bordering countries, including China and Japan, where a distinct set of HIV subtypes is circulating, such as B′, C, and CRF01_AE. The distribution of HIV-1 genetic variants in the cities studied was as follows: subtype A (IDU-A), 55.7%; subtype B, 25.3% (IDU-B variant—24.3%); subtype C, 10.0%; CRF02_AG, 1.5%; and CRF63_02A1, 7.5%. A phylogenetic analysis confirmed the relationship of subtype A viruses with the IDU-A variant predominating in Ukraine, Russia and other former Soviet Union (FSU) countries, of subtype B viruses with IDU-B in the Ukraine and of CRF02_AG variants with variants in Uzbekistan, Russia, and other former USSR countries. Subtype C sequences were not uniform, and most clustered between each other and HIV-1 sequences originating from Africa; there was only one sample possibly related to Chinese variants. Thus, despite close cultural and commercial relationships among Russia, China, and Japan, the distribution of HIV-1 subtypes in the Russian Far East is still primarily influenced by contacts with the countries of the former USSR. PMID:24773167
Pasch, Whitney; Costales, Cristina; Siddiqi, Imran; Mohrbacher, Ann
Intravascular large B-cell lymphoma (IVLBCL) is a rare and deadly malignancy involving the growth of lymphoma cells within vessel lumina of all organ types. IVLBCL is further divided into the hemophagocytic Asian variant and a classical Western variant. Both variants are difficult to diagnose by imaging, and although diagnostic criteria have been developed to guide workup, histopathological examination remains imperative. Treatment of IVLBCL remains difficult given the high mortality of the disease, but rituximab has emerged as a promising therapeutic option when combined with various cytotoxic regimens. The two main variants of IVLBCL generally manifest in their respective Asian or Western populations, and crossover between ethnicities is rare. We present the second described case of Asian-variant IVLBCL in an African American individual.
Four East Asian winter monsoon (EAWM) indices are compared in this paper. In the research periods, all the indices show similar interannual and decadal-interdecadal variations, with predominant periods centering in 3-4 years, 6.5 years and 9-15 years, respectively. Besides, all the indices show remarkable weakening trends since the 1980s. The correlation coefficient of each two indices is positive with a significance level of 99%. Both the correlation analyses and the composites indicate that in stronger EAWM years, the Siberian high and the higher-level subtropical westerly jet are stronger, and the Aleutian low and the East Asia trough are deeper. This circulation pattern is favorable for much stronger northwesterly wind and lower air temperature in the subtropical regions of East Asia, while it is on the opposite in weaker EAWM years. Besides, EAWM can also exert a remarkable leading effect on the summer monsoon. After stronger (weaker) EAWM, less (more) summer precipitation is seen over the regions from the Yangtze River valley of China to southern Japan, while more (less) from South China Sea to the tropical western Pacific.
Wang, Bin; Wu, Renguang; Fu, Xiouhua
Observational evidence is presented to show a teleconnection between the central Pacific and East Asia during the extreme phases of ENSO cycles. This Pacific-East Asian teleconnection is confined to the lower troposphere. The key system that bridges the warm (cold) events in the eastern Pacific and the weak (strong) East Asian winter monsoons is an anomalous lower-tropospheric anticyclone (cyclone) located in the western North Pacific. The western North Pacific wind anomalies develop rapidly in late fall of the year when a strong warm or cold event matures. The anomalies persist until the following spring or early summer, causing anomalously wet (dry) conditions along the East Asian polar front stretching from southern China northeastward to the east of Japan (Kuroshio extension).Using atmospheric general circulation and intermediate models, the authors show that the anomalous Philippine Sea anticyclone results from a Rossby-wave response to suppressed convective heating, which is induced by both the in situ ocean surface cooling and the subsidence forced remotely by the central Pacific warming. The development of the anticyclone is nearly concurrent with the enhancement of the local sea surface cooling. Both the anticyclone and the cooling region propagate slowly eastward. The development and persistence of the teleconnection is primarily attributed to a positive thermodynamic feedback between the anticyclone and the sea surface cooling in the presence of mean northeasterly trades. The rapid establishment of the Philippine Sea wind and SST anomalies implies the occurrence of extratropical-tropical interactions through cold surge-induced exchanges of surface buoyancy flux. The central Pacific warming plays an essential role in the development of the western Pacific cooling and the wind anomalies by setting up a favorable environment for the anticyclone-SST interaction and midlatitude-tropical interaction in the western North Pacific.
Fowler, Darren M.; Glenwright, Brittni J.; Bhatia, Maneet; Drapeau, Martin
This study investigated whether East Asians differ from Caucasian Canadians in their expectations about counselling. Participants in this study included 31 East Asian and 53 Caucasian Canadian university students. The East Asian participants were all first-generation East Asians living in Canada, originally from China, Korea, Japan, or Vietnam.…
Discusses autonomy in language related to East-Asian contexts, describing autonomy in language learning, proposing a framework for learners in all contexts, examining three sources of sociocultural influence that could affect students' approaches to learning in East Asia, and considering attitudes and habits of learning that might result from such…
Lee, Sok K
The art of dying well has been a quintessential subject of ethicoreligious matters among the people in the West and the East. Most of us wish to die at home; however, about 50% of Americans die in acute care hospitals. Furthermore, immigrants from East Asian cultures feel more uncomfortable near death, because their physicians are not familiar with their traditions. This article is written to help American physicians understand the unique aspects of East Asian Confucian Ethics for the better care of the dying elderly. Western attitudes toward death are briefly reviewed and the six East Asian concepts related to death are elaborated from Confucian Chinese philosophy. To widen the horizon of bioethics and to embrace the Confucian wisdom of dying well, three pearls of wisdom from classical Confucianism are proposed: the relational autonomy of family, Confucian creative self-transformation, and the unity of transcendence and the human being. PMID:20740092
Prieler, Michael; Ivanov, Alex; Hagiwara, Shigeru
In this study, 432 television advertisements from Hong Kong, Japan, and South Korea were analyzed to determine their representations of older people. Findings demonstrate that in East Asian advertisements, older people are highly underrepresented, appear in major roles, mostly alongside younger people, and older men clearly outnumber older women. The other variables investigated (i.e., setting and product categories) led to no conclusive findings for the three societies. In short, our study, employing ethnolinguistic vitality theory to analyze television advertisements, demonstrates how East Asian societies greatly marginalize older people. Potential effects of such representations are discussed using social cognitive theory and cultivation theory.
Hong, Ja-Young; Ahn, Joong-Bae; Jhun, Jong-Ghap
The changes in the winter climatology and variability of the East Asian winter monsoon (EAWM) for the late 21st century (2070-2099) under the Representative Concentration Pathway (RCP) 4.5 and 8.5 scenarios are projected in terms of EAWM indices (EAWMIs). Firstly, the capability of the climate models participating in the Coupled Model Intercomparison Project phase 5 (CMIP5) in simulating the boreal winter climatology and the interannual variability of the EAWM for the late 20th century (1971-2000) is examined. Nine of twenty-three climate models are selected based on the pattern correlations with observation and a multi-model ensemble is applied to the nine model data. Three of twelve EAWMIs that show the most significant temporal correlations between the observation and CMIP5 surface air temperatures are utilized. The ensemble CMIP5 is capable of reproducing the overall features of the EAWM in spite of some biases in the region. The negative correlations between the EAWMIs and boreal winter temperature are well reproduced and 3-5 years of the major interannual variation observed in this region are also well simulated according to power spectral analyses of the simulated indices. The fields regressed onto the indices that resemble the composite strong winter monsoon pattern are simulated more or less weakly in CMIP5 compared to the observation. However, the regressed fields of sea level pressure, surface air temperature, 500-hPa geopotential height, and 300-hPa zonal wind are well established with pattern correlations above 0.83 between CMIP5 and observation data. The differences between RCPs and Historical indicate strong warming, which increases with latitude, ranging from 1 to 5 °C under RCP4.5 and from 3 to 7 °C under RCP8.5 in the East Asian region. The anomalous southerly winds generally become stronger, implying weaker EAWMs in both scenarios. These features are also identified with fields regressed onto the indices in RCPs. The future projections reveal
Avataneo, Chiara; Sablier, Michel
We report a pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) method capable of analyzing traditional East Asian papers. The method proposed is based on rapid and easy single step Py-GC/MS analysis that can be carried out with a minimum amount of matter, in the few microgram range. Three reference papers manufactured from kozo (Broussonetia kazinoki Siebold & Zucc.), mitsumata (Edgeworthia chrysantha Lindl.), and gampi (Wikstroemia sikokiana Franch. & Sav.) with the traditional hand paper making processes were examined. The method allows discrimination between terpenic and steroid compounds, which were revealed as chemical markers of origin of the plant fibers. Each paper investigated was found to have characteristic pyrolysis fingerprints that were unique to the traditional handmade paper, demonstrating the potential for differentiation of these biochemical components of fiber plants on East Asian papers towards identification and conservation of cultural heritage. The investigation on Py-GC/MS was extended to liquid extraction followed by GC/MS analysis to characterize the biochemical components of fiber plants. The main contribution of this study is to provide molecular criteria for discriminating plant species used for traditional East Asian hand papermaking. Py-GC/MS complements efficiently microscope identification especially for adverse cases. A case study of archaeological Chinese paper painting artefacts was thereafter successfully investigated to address informative potential and efficiency of the criteria of identification on ancient and degraded East Asian paperworks.
Discusses special aspects of East Asian collections and explores how organizational changes in academic libraries affect them, based on experiences at the University of Arizona. Considers total quality management; continuous quality improvement; teamwork; staffing changes; specialization versus generalization; budgetary restraints and cost…
Mou, Chunyan; Thomason, Helen A; Willan, Pamela M; Clowes, Christopher; Harris, W Edwin; Drew, Caroline F; Dixon, Jill; Dixon, Michael J; Headon, Denis J
Hair morphology differs dramatically between human populations: people of East Asian ancestry typically have a coarse hair texture, with individual fibers being straight, of large diameter, and cylindrical when compared to hair of European or African origin. Ectodysplasin-A receptor (EDAR) is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family involved in the development of hair follicles, teeth, and sweat glands. Analyses of genome-wide polymorphism data from multiple human populations suggest that EDAR experienced strong positive selection in East Asians. It is likely that a nonsynonymous SNP in EDAR, rs3827760, was the direct target of selection as the derived p.Val370Ala variant is seen at high frequencies in populations of East Asian and Native American origin but is essentially absent from European and African populations. Here we demonstrate that the derived EDAR370A common in East Asia has a more potent signaling output than the ancestral EDAR370 V in vitro. We show that elevation of Edar activity in transgenic mice converts their hair phenotype to the typical East Asian morphology. The coat texture becomes coarse, with straightening and thickening of individual hairs and conversion of fiber cross-sectional profile to a circular form. These thick hair fibers are produced by enlarged hair follicles, which in turn develop from enlarged embryonic organ primordia. This work shows that the multiple differences in hair form between East Asian and other human populations can be explained by the simplest of genetic alterations.
Yang, Song; Lau, K.-M.; Kim, K.-M.
Interannual variability of the wintertime East Asian westerly jet stream and the linkage between this variability and the Asian-Pacific climate are investigated. The study emphasizes on the variability of the jet core and its association with the Asian winter monsoon, tropical convection, upper tropospheric wave patterns, and the teleconnection of the jet with other climate systems. The relationship between the jet and North Pacific sea surface temperature pattern (SST) is also explored. NCEP/NCAR reanalysis, NASA GISS surface temperature, NASA GEOS reanalysis, NOAA reconstructed SST, GPCP precipitation, and NOAA snow cover data sets are analyzed in this study. An index of the East Asian jet has been defined by the December-February means of the 200 mb zonal winds that are averaged within a box enclosing the jet maximum, which shifts only moderately from one year to another especially in the south-north direction. The jet links to a teleconnection pattern whose major climate anomalies appear over the Asian continent and western Pacific (west of the dateline). This pattern differs distinctly from the teleconnection pattern associated with El Nino/Southern Oscillation (ENSO), which causes the Pacific/North American pattern to the east of the dateline. A strong jet is accompanied clearly by an increase in the intensity of the atmospheric circulation over Asia and the Pacific. In particular, the winter monsoon strengthens over East Asia, leading to cold climate in the region, and convection intensifies over the tropical Asia-Australia sector. Changes in the jet are associated with broad-scale modification in the upper tropospheric wave patterns that leads to downstream climate anomalies over the eastern Pacific. Through this downstream influence, the East Asian jet causes climate signals in North America as well. A strong jet gives rise to warming and less snow cover in the western United States but reverse climate anomalies in the eastern part of the country, although
Shouse, Roger C.; Ma, Chenwei
Over the past two decades, the concepts of educational creativity and leadership have attracted tremendous attention throughout East Asia. Driven in large part by isomorphic tendencies within a global organizational environment, the two ideas have also acquired the trappings of institutional myth. Often overlooked in the schools literature,…
Brucato, Nicolas; Mazières, Stéphane; Guitard, Evelyne; Giscard, Pierre-Henri; Bois, Etienne; Larrouy, Georges; Dugoujon, Jean-Michel
The Hmong Diaspora is one of the widest modern human migrations. Mainly localised in South-East Asia, the United States of America, and metropolitan France, a small community has also settled the Amazonian forest of French Guiana. We have biologically analysed 62 individuals of this unique Guianese population through three complementary genetic markers: mitochondrial DNA (HVS-I/II and coding region SNPs), Y-chromosome (SNPs and STRs), and the Gm allotypic system. All genetic systems showed a high conservation of the Asian gene pool (Asian ancestry: mtDNA=100.0%; NRY=99.1%; Gm=96.6%), without a trace of founder effect. When compared across various Asian populations, the highest correlations were observed with Hmong-Mien groups still living in South-East Asia (Fst<0.05; P-value<0.05). Despite a long history punctuated by exodus, the French Guianese Hmong have maintained their original genetic diversity.
Styrkarsdottir, Unnur; Halldorsson, Bjarni V; Gudbjartsson, Daniel F; Tang, Nelson L S; Koh, Jung-Min; Xiao, Su-mei; Kwok, Timothy C Y; Kim, Ghi Su; Chan, Juliana C N; Cherny, Stacey; Lee, Seung Hun; Kwok, Anthony; Ho, Suzanne; Gretarsdottir, Solveig; Kostic, Jelena Pop; Palsson, Stefan Th; Sigurdsson, Gunnar; Sham, Pak C; Kim, Beom-Jun; Kung, Annie W C; Kim, Shin-Yoon; Woo, Jean; Leung, Ping-C; Kong, Augustine; Thorsteinsdottir, Unnur; Stefansson, Kari
Most genome-wide association (GWA) studies have focused on populations of European ancestry with limited assessment of the influence of the sequence variants on populations of other ethnicities. To determine whether markers that we have recently shown to associate with Bone Mineral Density (BMD) in Europeans also associate with BMD in East-Asians we analysed 50 markers from 23 genomic loci in samples from Korea (n = 1,397) and two Chinese Hong Kong sample sets (n = 3,869 and n = 785). Through this effort we identified fourteen loci that associated with BMD in East-Asian samples using a false discovery rate (FDR) of 0.05; 1p36 (ZBTB40, P = 4.3×10(-9)), 1p31 (GPR177, P = 0.00012), 3p22 (CTNNB1, P = 0.00013), 4q22 (MEPE, P = 0.0026), 5q14 (MEF2C, P = 1.3×10(-5)), 6q25 (ESR1, P = 0.0011), 7p14 (STARD3NL, P = 0.00025), 7q21 (FLJ42280, P = 0.00017), 8q24 (TNFRSF11B, P = 3.4×10(-5)), 11p15 (SOX6, P = 0.00033), 11q13 (LRP5, P = 0.0033), 13q14 (TNFSF11, P = 7.5×10(-5)), 16q24 (FOXL1, P = 0.0010) and 17q21 (SOST, P = 0.015). Our study marks an early effort towards the challenge of cataloguing bone density variants shared by many ethnicities by testing BMD variants that have been established in Europeans, in East-Asians.
Lee, Haeok; Kim, Sun S; You, Kwang Soo; Park, Wanju; Yang, Jin Hyang; Kim, Minjin; Hayman, Laura L
Alcohol use can lead to a cascade of problems such as increased chances of risky behavior and negative health consequences, including alcoholic liver disease and upper gastric and liver cancer. Ethanol is metabolized mainly by 2 major enzymes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH). Genetic variations of genes encoding the 2 enzymes are very common among East Asians but relatively rare for most other populations. Facial flushing and other physical discomforts after alcohol drinking triggered by accumulation of acetaldehyde through defective genes for ADH and ALDH have been reported. Approximately 40% of East Asians (Chinese, Japanese, and Korean) show facial flushing after drinking alcohol, known as "Asian flush," which is characterized by adverse reactions on alcohol drinking in individuals possessing the fasting metabolizing alleles for ADH, ADH1B*2, and ADH1C*1, and the null allele for ALDH and ALDH2*2. Alcoholism is determined not only by the genetic deficiency but also by behaviors that involve complex interactions between genetic and sociocultural factors. The purpose of this article was to provide nurses with the most current information about genetic and sociocultural influences on alcoholism and alcohol-related health problems specifically for East Asians and implications of this knowledge to nursing practice. The physiological phenomenon of genes and genetics in relation to alcohol metabolism in this special population is emphasized.
suggest, as the US defense establishment must, that a trade war with Japan would endanger higher political and military interests is a difficult...standi is weak, but the case of security con- siderations must be pressed. The third lever that might move Japan is related to the first- defense ... Japan and the East Asian Balance of Power JEROME K. HOLLOWAY T hirteen years after the collapse of the American enterprise in Vietnam, there
A small group of high-performing East Asian economies dominate the top of the Programme for International Student Assessment (PISA) rankings. This has caught the attention of Western policymakers, who want to know why East Asian children obtain such high PISA scores, and what can be done to replicate their success. In this paper I investigate…
Yang, Song; Lau, K.-M.; Kim, K.-M.
The upper-tropospheric westerly jet stream over subtropical East Asia and western Pacific, often referred to as East Asian Jet (EAJ), is an important atmospheric circulation system in the Asian-Pacific-American (APA) region during winter. It is characterized by variabilities on a wide range of time scales and exerts a strong impact on the weather and climate of the region. On the synoptic scale, the jet stream is closely linked to many phenomena such as cyclogenesis, frontogenesis, blocking, storm track activity, and the development of other atmospheric disturbances. On the seasonal time scale, the variation of the EAJ determines many characteristics of the seasonal transition of the atmospheric circulation especially over East Asia. The variabilities of the EAJ on these time scales have been relatively well documented. It has also been understood since decades ago that the interannual. variability of the EAJ is associated with many climate signals in the APA region. These signals include the persistent anomalies of the East Asian winter monsoon and the changes in diabatic heating and in the Hadley circulation. However, many questions remain for the year-to-year variabilities of the EAJ and their relation to the APA climate. For example, what is the relationship between the EAJ and El Nino/Southern Oscillation (ENSO)? Will the EAJ and ENSO play different roles in modulating the APA climate? How is the jet stream linked to the non-ENSO-related sea surface temperature (SST) anomalies and to the Pacific/North American (PNA) teleconnection pattern?
Chen, Yuan; Xue, Yali; Luiselli, Donata; Tyler-Smith, Chris; Pagani, Luca; Ayub, Qasim
Vitamin D and folate are activated and degraded by sunlight, respectively, and the physiological processes they control are likely to have been targets of selection as humans expanded from Africa into Eurasia. We investigated signals of positive selection in gene sets involved in the metabolism, regulation and action of these two vitamins in worldwide populations sequenced by Phase I of the 1000 Genomes Project. Comparing allele frequency-spectrum-based summary statistics between these gene sets and matched control genes, we observed a selection signal specific to East Asians for a gene set associated with vitamin D action in bones. The selection signal was mainly driven by three genes CXXC finger protein 1 (CXXC1), low density lipoprotein receptor-related protein 5 (LRP5) and runt-related transcription factor 2 (RUNX2). Examination of population differentiation and haplotypes allowed us to identify several candidate causal regulatory variants in each gene. Four of these candidate variants (one each in CXXC1 and RUNX2 and two in LRP5) had a >70% derived allele frequency in East Asians, but were present at lower (20–60%) frequency in Europeans as well, suggesting that the adaptation might have been part of a common response to climatic and dietary changes as humans expanded out of Africa, with implications for their role in vitamin D-dependent bone mineralization and osteoporosis insurgence. We also observed haplotype sharing between East Asians, Finns and an extinct archaic human (Denisovan) sample at the CXXC1 locus, which is best explained by incomplete lineage sorting. PMID:26719974
de Grijs, Richard; Zhang, Ziping; He, Jinhua
At the 2012 General Assembly of the International Astronomical Union (IAU), the Office of Astronomy for Development announced a number of exciting new partnerships to assist with the IAU's decadal strategic plan (2010-2020). These landmark decisions included establishing a new coordinating centre that aims at using astronomy as a tool for development in East Asia. The agreement covers two important functions. One is known as a Regional Node, which entails the coordination of astronomy-for-development activities in countries within the general geographical region of East Asia. The other is known as a Language Expertise Centre which deals with all aspects relating to (mainly) the Chinese language and culture. The impact of the latter may obviously spread well beyond the geographical region to other parts of the world. Here we provide an update of the achievements and aims of the East Asian Office of Astronomy for Development.
Tateno, Yoshio; Komiyama, Tomoyoshi; Katoh, Toru; Munkhbat, Batmunkh; Oka, Akira; Haida, Yuko; Kobayashi, Hiroyuki; Tamiya, Gen; Inoko, Hidetoshi
To study the male and female lineages of East Asian and European humans, we have sequenced 25 short tandem repeat markers on 453 Y-chromosomes and collected sequences of 72 complete mitochondrial genomes to construct independent phylogenetic trees for male and female lineages. The results indicate that East Asian individuals fall into two clades, one that includes East Asian individuals only and a second that contains East Asian and European individuals. Surprisingly, the European individuals did not form an independent clade, but branched within in the East Asians. We then estimated the divergence time of the root of the European clade as ∼41,000 years ago. These data indicate that, contrary to traditional views, Europeans diverged from East Asians around that time. We also address the origin of the Ainu lineage in northern Japan. PMID:24589501
Maker, Azmaira H.; Shah, Priti V.; Agha, Zia
The present study examined the prevalence, characteristics, beliefs, and demographic predictors of parent-child physical violence among South Asian, Middle Eastern, East Asian, and Latina women in the United States. Two hundred fifty-one college-educated women from a middle to high SES (South Asian/Middle Eastern, n = 93; East Asian, n = 72;…
Zhang, Shuyan; Li, Xuling; Ma, Guoda; Jiang, Yongshuai; Liao, Mingzhi; Feng, Rennan; Zhang, Liangcai; Liu, Jiafeng; Wang, Guangyu; Zhao, Bin; Jiang, Qinghua; Li, Keshen; Liu, Guiyou
Large-scale genome-wide association studies (GWAS) identified three single nucleotide polymorphisms rs11136000, rs2279590, and rs9331888 in CLU gene to be significantly associated with Alzheimer's disease (AD) in Caucasian ancestry. Both rs11136000 and rs2279590 variants were successfully replicated in Asian population. However, previous studies reported either a weak association or no association between rs9331888 polymorphism and AD in Asian population. Here, we searched the PubMed, AlzGene, and Google Scholar databases. We selected 12 independent studies that evaluated the association between the rs9331888 polymorphism and AD using a case-control design. Using an additive model, we did not identify significant heterogeneity among these 12 studies. We observed significant association between rs9331888 polymorphism and AD in pooled populations (P = 2.26E - 07, odds ratio (OR) = 1.10, 95% confidence interval (CI) 1.06-1.14). In subgroup analysis, we did not identify significant heterogeneity in both Asian and Caucasian populations. We identified significant association in Caucasian population (P = 1.67E - 08, OR = 1.13, 95% CI 1.08-1.18) but not in East Asian population (P = 0.49, OR = 1.02, 95% CI 0.96-1.10).
Gong, Dao-Yi; Mao, Rui; Shi, Pei-Jun; Fan, Yi-Da
Large-scale climate teleconnections play evident roles in spring dust storm variability over east Asia through influencing regional weather and climates. In the present study authors found that dust storm frequency in northern China is significantly correlated to the Pacific/North American (PNA) pattern with a Pearson's correlation coefficient of +0.60 on interannual time scale during the period 1962-2002. The atmospheric circulation changes (including weather disturbances at 850hPa, monthly mean wind and height at 500 hPa and 200 hPa levels) in association with dust storm and PNA bear remarkable similarity, confirming the robustness of their connections. East Asian jet stream is, at least partly, responsible for generating the evident co-variations between dust storm frequency and PNA. This teleconnection and the corresponding circulation changes exist in non-El Niño/Southern Oscillation (ENSO), likely independent of ENSO phases. The results are helpful for better understanding how East Asian dust storm responds to the global change.
Wei, Ke; Chen, Wen; Zhou, Wen
Using NCEP-NCAR reanalysis data and observational data from meteorological stations in China, the evolution of the East Asian cold season (EACS) and its long-term changes after 2000 were studied. A monsoon tendency index (MTI), defined as the temporal difference of the East Asian monsoon index, indicates that the winter monsoon setup has been postponed in autumn, while the setup has quickened in early winter. In mid winter, the EACS breakdown process has accelerated, while it has lingered in late winter. The authors suggest that the postponement of monsoon setup in autumn may be caused by strong global warming at the lower levels, which further limits the setup time period and leads to the quickening of the setup process in early winter. Meanwhile, a north-south seesaw of temperature tendency change in China can be observed in December and February, which may be related to large-scale circulation changes in the stratosphere, characterized by a polar warming in mid winter and polar cooling in early spring. This linkage is possibly caused by the dynamical coupling between stratosphere and troposphere, via the variation of planetary wave activities. In spring, the speed of the EACS breakdown has decreased, which favors the revival of the EACS in East Asia.
He, Jinhai; Liu, Boqi
The East Asian subtropical summer monsoon (EASSM) is one component of the East Asian summer monsoon system, and its evolution determines the weather and climate over East China. In the present paper, we firstly demonstrate the formation and advancement of the EASSM rainbelt and its associated circulation and precipitation patterns through reviewing recent studies and our own analysis based on JRA-55 (Japanese 55-yr Reanalysis) data and CMAP (CPC Merged Analysis of Precipitation), GPCP (Global Precipitation Climatology Project), and TRMM (Tropical Rainfall Measuring Mission) precipitation data. The results show that the rainy season of the EASSM starts over the region to the south of the Yangtze River in early April, with the establishment of strong southerly wind in situ. The EASSM rainfall, which is composed of dominant convective and minor stratiform precipitation, is always accompanied by a frontal system and separated from the tropical summer monsoon system. It moves northward following the onset of the South China Sea summer monsoon. Moreover, the role of the land-sea thermal contrast in the formation and maintenance of the EASSM is illustrated, including in particular the effect of the seasonal transition of the zonal land-sea thermal contrast and the influences from the Tibetan Plateau and midlatitudes. In addition, we reveal a possible reason for the subtropical climate difference between East Asia and East America. Finally, the multi-scale variability of the EASSM and its influential factors are summarized to uncover possible reasons for the intraseasonal, interannual, and interdecadal variability of the EASSM and their importance in climate prediction.
Isobe, Atsuhiko; Uchida, Keiichi; Tokai, Tadashi; Iwasaki, Shinsuke
To investigate concentrations of pelagic micro- (<5mm in size) and mesoplastics (>5mm) in the East Asian seas around Japan, field surveys using two vessels were conducted concurrently in summer 2014. The total particle count (pieces km(-2)) was computed based on observed concentrations (pieces m(-3)) of small plastic fragments (both micro- and mesoplastics) collected using neuston nets. The total particle count of microplastics within the study area was 1,720,000 pieces km(-2), 16 times greater than in the North Pacific and 27 times greater than in the world oceans. The proportion of mesoplastics increased upstream of the northeastward ocean currents, such that the small plastic fragments collected in the present surveys were considered to have originated in the Yellow Sea and East China Sea southwest of the study area.
Zhangqing, Li; Li, C.; Chen, H.; Tsay, S.-C.; Holben, B.; Huang, J.; Li, B.; Maring, H.; Qian, Y.; Shi, G.; Xia, X.; Yin, Y.; Zheng, Y.; Zhuang, G.
As the most populated region of the world, Asia is a major source of aerosols with potential large impact over vast downstream areas, Papers published in this special section describe the variety of aerosols observed in China and their effects and interactions with the regional climate as part of the East Asian Study of Tropospheric Aerosols and their Impact on Regional Climate (EAST-AIRC), The majority of the papers are based on analyses of observations made under three field projects, namely, the Atmospheric Radiation Measurements (ARM) Mobile Facility mission in China (AMF-China), the East Asian Study of Tropospheric Aerosols: An International Regional Experiment (EAST-AIRE), and the Atmospheric Aerosols of China and their Climate Effects (AACCE), The former two are U,S,-China collaborative projects, and the latter is a part of the China's National Basic Research program (or often referred to as "973 project"), Routine meteorological data of China are also employed in some studies, The wealth of general and speCIalized measurements lead to extensive and close-up investigations of the optical, physical, and chemical properties of anthropogenic, natural, and mixed aerosols; their sources, formation, and transport mechanisms; horizontal, vertical, and temporal variations; direct and indirect effects; and interactions with the East Asian monsoon system, Particular efforts are made to advance our understanding of the mixing and interaction between dust and anthropogenic pollutants during transport. Several modeling studies were carried out to simulate aerosol impact on radiation budget, temperature, precipitation, wind and atmospheric circulation, fog, etc, In addition, impacts of the Asian monsoon system on aerosol loading are also simulated.
Murray, Nicole; Norton, Heather L; Parra, Esteban J
Two OCA2 polymorphisms (rs1800414 and rs74653330) have been associated with pigmentation in East Asians. We explored the distribution of these markers in a panel of samples from populations around the world. The derived allele of rs1800414 has high frequencies in a broad East-Asian region, whereas the derived allele of rs74653330 is primarily restricted to northern East Asia. Our data suggest that these polymorphisms may have been selected independently in different regions of East Asia. PMID:27081560
Tsuchie, H; Saraswathy, T S; Sinniah, M; Vijayamalar, B; Maniar, J K; Monzon, O T; Santana, R T; Paladin, F J; Wasi, C; Thongcharoen, P
HIV spread in South and South-East Asia is most alarming, and genetic variability of HIV-1 is an important consideration in vaccine development. In this study, we examined the third variable (V3) region of env gene of HIV-1 variants prevalent in Thailand, Malaysia, India, and the Philippines. By phylogenetic tree analyses, an HIV-1 variant from an injecting drug user (IDU) in Thailand belonged to subtype B, and HIV-1 variants from 2 IDUs in Malaysia were classified into 2 subtypes, B and E. One HIV-1 variant from a male homosexual in the Philippines belonged to subtype B. Out of 8 HIV-1 variants from sexually transmitted disease patients in India, 7 belonged to subtype C, and one to subtype A. Although the total number of individuals examined in this study was limited, 4 HIV-1 subtypes were found in South and South-East Asia and large international movements of HIV-1-infected individuals in this region could induce global dissemination of these HIV-1 variants.
Chen, Yen-Yuan; Tsai, Shih-Li; Yang, Chih-Wei; Ni, Yen-Hsuan; Chang, Shan-Chwen
Family autonomy/family-determination (FA/FD) is deeply rooted in Confucianism, and is an important core value in East Asian biomedical ethics. Individual autonomy/self-determination (IA/SD) did not originate in East Asia, and is the most important core value of Western biomedical ethics. IA/SD and FA/FD are different from each other not only because of where they originated but also in their general sense and moral foundations. We investigated the influence of Western biomedical ethics on the Eastern hemisphere. We examined the secular trends of IA/SD use in ethics and biomedical ethics articles published in Taiwan from 1991 to 2010. The published articles were collected from a popular online library called the Chinese Electronic Periodical Services. A total of 1737 articles were associated with ethics, and 300 of them were associated with biomedical ethics. The total number of times IA/SD was used in each ethics and biomedical ethics article was calculated. The secular trends were plotted graphically and analyzed by time series linear regression analysis. The results showed that the secular trend of the proportion of the yearly total of biomedical ethics articles to the yearly total of ethics articles was significantly increasing (p = 0.007). The secular trends of the average of times IA/SD showed that one unit of yearly increase was associated with an increment of 0.056 IA/SD use per ethics article (p < 0.001), and 0.331 IA/SD use per biomedical ethics article (p = 0.027), respectively. These findings suggest that Western biomedical ethics have become increasingly influential in Taiwan over the past two decades. Thus, assuming that FA/FD takes priority over IA/SD in an East Asian medical encounter is too simplistic. Whether FA/FD or IA/SD takes priority in a medical encounter should be carefully evaluated.
Dhillon, Jasmin; Horch, Jenny D; Hodgins, David C
Cultural influences on problem gambling stigma were examined using a between subject vignette study design. Students of East Asian (n = 64) and Caucasian (n = 50) ancestry recruited from a Canadian University rated a vignette describing either an East Asian problem gambler or a Caucasian problem gambler on a measure of attitudinal social distance. In accordance with the hypothesis, a factorial ANOVA revealed that East Asian Canadians stigmatize problem gambling more than Caucasian Canadians. Moreover, East Asian participants stigmatized the East Asian individual described in the vignette more than they did the Caucasian individual. Individuals with gambling problems were generally not perceived as being dangerous. However, participants who perceived problem gambling as a dangerous condition wanted more social distance than those who did not perceive individuals with a gambling problem as dangerous.
de Grijs, Richard; Zhang, Ziping
At the 2012 General Assembly of the International Astronomical Union (IAU), the Office of Astronomy for Development (OAD) programme announced a number of exciting new partnerships to assist with the IAU's decadal strategic plan (2010-2020). These landmark decisions included establishing a new coordinating centre that aims at using astronomy as a tool for development in East Asia. The agreement covers two important functions. One is known as a Regional Node, which entails the coordination of astronomy-for-development activities in countries within the general geographical region of East Asia (in first instance China, Mongolia and the DPRK, but without placing firm geographical limits on the region). The other is known as a Language Expertise Centre which will deal with all aspects relating to (mainly) the Chinese language and culture. The impact of the latter may obviously spread well beyond the geographical region to other parts of the world. At this next General Assembly, we aim at updating the community of the achievements and aims of the East Asian Office of Astronomy for Development.
Yang, Song; Lau, K.-M.; Kim, K.-M.
The wintertime upper-tropospheric westerly jet stream over subtropical East Asia and western Pacific, often referred to as East Asian Jet (EAJ), is an important atmospheric circulation system in the Asian-Pacific-American (APA) region. It is characterized by variabilities on a wide range of time scales and exerts a strong impact on the weather and climate of the region. On the synoptic scale, the jet is closely linked to many phenomena such as cyclogenesis, frontogenesis, blocking, storm track activity, and the development of other atmospheric disturbances. On the seasonal time scale, the variation of the EAJ determines many characteristics of the seasonal transition of the atmospheric circulation over Asia. The variabilities of the jet on these time scales have been relatively well documented (e.g., Yeh et al. 1959, Palmen and Newton 1969; Zeng 1979). It has also been understood that the inter-annual variability of the EAJ is associated with many climate signals in the APA region. These signals include the persistent anomalies of the East Asian winter monsoon and the changes in diabatic heating and in the Hadley circulation (Bjerknes 1966; Chang and Lau 1980; Huang and Gambo 1982; Kang and Held 1986; Tao and Chen 1987; Lau et al. 1988; Yang and Webster 1990; Ding 1992; Webster and Yang 1992; Dong et al. 1999). However, many questions remain for the year-to-year variabilities of the jet and their relation to the APA climate. For example, what is the relationship between the EAJ and El Nino/Southern Oscillation (ENSO)? Will the jet and ENSO play different roles in modulating the APA climate? How is the jet linked to North Pacific sea surface temperature (SST) and the Pacific/North American (PNA) teleconnection pattern? In this study, we address several issues related to the wintertime EAJ with a focus on interannual time scales. We will examine the association between the jet core and ENSO, which has always been overshadowed by the relationship between ENSO and the
Wagner, Thomas W.; Shuchman, Robert A.
By all economic measures East and Southeast Asia are major success stories and emerging powerhouses in the global economy. This region continues to outperform, by a wide margin, other regions of the developing world and the industrial countries as well. However, this economic growth has been at a cost to the environment that is increasingly evident and may threaten future growth. Losses of tropical forests, unsustainable agriculture, unsound energy production and use, urban and industrial pollution, and the depletion of coastal and marine resources all impact current and future growth. However, information obtained from Mission-To-Planet-Earth sensors and other remote sensing devices may provide a basis for policies that help reduce environmental damage and promote resource sustainability. Three examples using Landsat, AVHRR, and interferometric RADAR data illustrate remote sensing applications to Asian development and environmental sustainability.
Kim, Young Uk; Kim, Young Jin; Lee, Jong-Young; Park, Kiejung
Genome-wide association studies (GWAS) have become popular as an approach for the identification of large numbers of phenotype-associated variants. However, differences in genetic architecture and environmental factors mean that the effect of variants can vary across populations. Understanding population genetic diversity is valuable for the investigation of possible population specific and independent effects of variants. EvoSNP-DB aims to provide information regarding genetic diversity among East Asian populations, including Chinese, Japanese, and Korean. Non-redundant SNPs (1.6 million) were genotyped in 54 Korean trios (162 samples) and were compared with 4 million SNPs from HapMap phase II populations. EvoSNP-DB provides two user interfaces for data query and visualization, and integrates scores of genetic diversity (Fst and VarLD) at the level of SNPs, genes, and chromosome regions. EvoSNP-DB is a web-based application that allows users to navigate and visualize measurements of population genetic differences in an interactive manner, and is available online at [http://biomi.cdc.go.kr/EvoSNP/]. [BMB Reports 2013; 46(8): 416-421] PMID:23977990
di Marco, Chiara F.; Phillips, Gavin J.; Thomas, Rick; Tang, Sim; Nemitz, Eiko; Sutton, Mark A.; Fowler, David; Lim, Sei F.
The supply of reactive nitrogen (N) to global terrestrial ecosystems has doubled since the 1960s as a consequence of human activities, such as fertilizer application and production of nitrogen oxides by fossil-fuel burning. The deposition of atmospheric N species constitutes a major nutrient input to the biosphere. Tropical forests have been undergoing a radical land use change by increasing cultivation of sugar cane and oil palms and the remaining forests are increasingly affected by anthropogenic activities. Yet, quantifications of atmospheric nitrogen deposition to tropical forests, and nitrogen cycling under near-pristine and polluted conditions are rare. The OP3 project ("Oxidant and Particle Photochemical Processes above a Southeast Asian Tropical Rainforest") was conceived to study how emissions of reactive trace gases from a tropical rain forest mediate the regional scale production and processing of oxidants and particles, and to better understand the impact of these processes on local, regional and global scale atmospheric composition, chemistry and climate. As part of this study we have measured reactive, nitrogen containing trace gas (ammonia, nitric acid) and the associated aerosol components (ammonium, nitrate) at monthly time resolution using a simple filter / denuder for 16 months. These measurements were made at the Bukit Atur Global Atmospheric Watch tower near Danum Valley in the Malaysian state of Sabah, Borneo. In addition, the same compounds were measured at hourly time-resolution during an intensive measurement period, with a combination of a wet-chemistry system based on denuders and steam jet aerosol collectors and an aerosol mass spectrometer (HR-ToF-AMS), providing additional information on the temporal controls. During this period, concentrations and fluxes of NO, NO2 and N2O were also measured. The measurements are used for inferential dry deposition modelling and combined with wet deposition data from the South East Asian Acid
Dallmeyer, Anne; Claussen, Martin; Ni, Jian; Wang, Yongbo; Cao, Xianyong; Herzschuh, Ulrike
East Asia is affected by three major atmospheric circulation systems determining the regional climate and vegetation distribution: The moisture advected by the Indian and East Asian monsoon support the growing of forest in large parts of Eastern China. The influence of the monsoon gets weaker further on the continent yielding a transition of forest to steppe and of steppe to desert in Central East Asia (e.g. Inner Mongolia) where the dry westerly winds prevail. Particularly in these transition zones, vegetation is supposed to be very sensitive to climate change and strong feedbacks are expected in case of climate and vegetation shifts due to large environmental changes (Feng et al., 2006). During mid-Holocene, cyclic variations in the Earth's orbit around the sun led to an enhancement of the Asian monsoon system probably causing strong shifts in the biome distribution. According to reconstructions, the steppe-forest margin moved to the northwest by about 500km (Yu et al., 2000) and the desert area in China and Inner Mongolia was substantially reduced compared to today (Feng et al., 2006). However, in the complex environment of Asia, the locally limited reconstructions may not portray the general vegetation change. To get a systematic overview on the spatial pattern of biome shifts in the Asian monsoon - westerly wind transition zone since mid-Holocene, we use the diagnostic vegetation model BIOME4 and force this model with climate anomalies from different transient Holocene climate simulations performed in coupled atmosphere-ocean-vegetation models. The main aims of this study are to a) get a consistent ensemble of possible changes in biome distribution since the mid-Holocene b) test the robustness of the simulated vegetation changes and quantify the differences between the models, and c) allow for a better comparison of simulated and reconstructed vegetation changes. Preliminary results confirm the general trend seen in the reconstructions. The simulations reveal
Jeong, Choongwon; Nakagome, Shigeki; Di Rienzo, Anna
Despite recent advances in population genomics, much remains to be elucidated with regard to East Asian population history. The Ainu, a hunter–gatherer population of northern Japan and Sakhalin island of Russia, are thought to be key to elucidating the prehistory of Japan and the peopling of East Asia. Here, we study the genetic relationship of the Ainu with other East Asian and Siberian populations outside the Japanese archipelago using genome-wide genotyping data. We find that the Ainu represent a deep branch of East Asian diversity more basal than all present-day East Asian farmers. However, we did not find a genetic connection between the Ainu and populations of the Tibetan plateau, rejecting their long-held hypothetical connection based on Y chromosome data. Unlike all other East Asian populations investigated, the Ainu have a closer genetic relationship with northeast Siberians than with central Siberians, suggesting ancient connections among populations around the Sea of Okhotsk. We also detect a recent genetic contribution of the Ainu to nearby populations, but no evidence for reciprocal recent gene flow is observed. Whole genome sequencing of contemporary and ancient Ainu individuals will be helpful to understand the details of the deep history of East Asians. PMID:26500257
Wang, Huaitang; Masuda, Takahiko; Ito, Kenichi; Rashid, Marghalara
Literature in cultural psychology suggests that compared with North Americans, East Asians prefer context-rich cultural products (e.g., paintings and photographs). The present article further examines the preferred amount of information in cultural products produced by East Asians and North Americans (Study 1: Society for Personality and Social Psychology conference posters; Study 2: government and university portal pages). The authors found that East Asians produced more information-rich products than did North Americans. Study 3 further examined people's information search speed when identifying target objects on mock webpages containing large amounts of information. The results indicated that East Asians were faster than North Americans in dealing with information on mock webpages with large amounts of information. Finally, the authors found that there were cultural differences as well as similarities in functional and aesthetic preferences regarding styles of information presentation. The interplay between cultural products and skills for accommodating to the cultural products is discussed.
Masuda, Takahiko; Gonzalez, Richard; Kwan, Letty; Nisbett, Richard E
Prior research indicates that East Asians are more sensitive to contextual information than Westerners. This article explored aesthetics to examine whether cultural variations were observable in art and photography. Study 1 analyzed traditional artistic styles using archival data in representative museums. Study 2 investigated how contemporary East Asians and Westerners draw landscape pictures and take portrait photographs. Study 3 further investigated aesthetic preferences for portrait photographs. The results suggest that (a) traditional East Asian art has predominantly context-inclusive styles, whereas Western art has predominantly object-focused styles, and (b) contemporary members of East Asian and Western cultures maintain these culturally shaped aesthetic orientations. The findings can be explained by the relation among attention, cultural resources, and aesthetic preference.
Homma, Yuko; Wong, Sabrina T; Zumbo, Bruno D; Saewyc, Elizabeth M
Despite the large number of East Asian youth in Canada, little is known about their health and risk behaviors. We examined the relationship between ethnic identity and sexual initiation among East Asians. This secondary analysis of a population-based survey selected 4,311 students in 7-12th grades who described themselves as East Asian (e.g., Chinese, Japanese, Korean). Gender-stratified logistic regression analyses examined whether ethnic identity was associated with sexual initiation, controlling for age, living situation, and cultural exposure. Boys with stronger commitment to their ethnic groups were less likely to have ever had sexual intercourse (aOR 0.80). Girls with higher levels of ethnic identity exploration were less likely to report sexual initiation (aOR 0.71). Stronger ethnic identity was associated with not having sexual intercourse among East Asian adolescents. The findings suggest the need to consider ethnocultural factors in future research and practice.
Gangoli, Geetanjali; McCarry, Melanie; Razak, Amina
This article addresses the links between child marriage and forced marriage in the UK, drawing from a research study on South Asian communities in North East England. It looks at definitional issues through an analysis of UK and South Asian policies. It also analyses how these concepts are understood by service providers, survivors of child…
Homma, Yuko; Chen, Weihong; Poon, Colleen S.; Saewyc, Elizabeth M.
The purpose of this study was to examine the relationship between substance use and sexual orientation among Asian adolescents in Canada. We analyzed an East- and Southeast-Asian subsample of a province-wide, school-based survey (weighted N = 51,349). Compared to heterosexual adolescents of the same gender, gay, lesbian, bisexual, and mostly…
Yang, Song; Lau, K.-M.; Kim, K.-M.; Einaudi, Franco (Technical Monitor)
In this study, the influences of the East Asian jet stream (EAJS) and El Nino/Southern Oscillation (ENSO) on the interannual variability of the East Asian winter climate are examined with a focus on the relative climate impacts of the two phenomena. Although the variations of the East Asian winter monsoon and the temperature and precipitation of China, Japan, and Korea are emphasized, the associated changes in the broad-scale atmospheric circulation patterns over Asia and the Pacific and in the extratropical North Pacific sea surface temperature (SST) are also investigated. It is demonstrated that there is no apparent relationship between ENSO and the interannual variability of EAJS core. The EAJS and ENSO are associated with distinctly different patterns of atmospheric circulation and SST in the Asian-Pacific regions. While ENSO causes major climate signals in the Tropics and over the North Pacific east of the dateline, the EAJS produces significant changes in the atmospheric circulation over East Asia and western Pacific. In particular, the EAJS explains larger variance of the interannual signals of the East Asian trough, the Asian continental high, the Aleutian low, and the East Asian winter monsoon. When the EAJS is strong, all these atmospheric systems intensify significantly. The response of surface temperature and precipitation to EAJS variability and ENSO is more complex. In general, the East Asian winter climate is cold (warm) and dry (wet) when the EAJS is strong (weak) and it is warm during El Nino years. However, different climate signals are found during different La Nina years. In terms of linear correlation, both the temperature and precipitation of northern China, Korea, and central Japan are more significantly associated with the EAJS than with ENSO.
Qin, Pengfei; Zhou, Ying; Lou, Haiyi; Lu, Dongsheng; Yang, Xiong; Wang, Yuchen; Jin, Li; Chung, Yeun-Jun; Xu, Shuhua
Historical records indicate that extensive cultural, commercial and technological interaction occurred between European and Asian populations. What have been the biological consequences of these contacts in terms of gene flow? We systematically estimated gene flow between Eurasian groups using genome-wide polymorphisms from 34 populations representing Europeans, East Asians, and Central/South Asians. We identified recent gene flow between Europeans and Asians in most populations we studied, including East Asians and Northwestern Europeans, which are normally considered to be non-admixed populations. In addition we quantitatively estimated the extent of this gene flow using two statistical approaches, and dated admixture events based on admixture linkage disequilibrium. Our results indicate that most genetic admixtures occurred between 2,400 and 310 years ago and show the admixture proportions to be highly correlated with geographic locations, with the highest admixture proportions observed in Central Asia and the lowest in East Asia and Northwestern Europe. Interestingly, we observed a North-to-South decline of European gene flow in East Asians, suggesting a northern path of European gene flow diffusing into East Asian populations. Our findings contribute to an improved understanding of the history of human migration and the evolutionary mechanisms that have shaped the genetic structure of populations in Eurasia.
Chen, Fahu; Xu, Qinghai; Chen, Jianhui; Birks, H. John B.; Liu, Jianbao; Zhang, Shengrui; Jin, Liya; An, Chengbang; Telford, Richard J.; Cao, Xianyong; Wang, Zongli; Zhang, Xiaojian; Selvaraj, Kandasamy; Lu, Houyuan; Li, Yuecong; Zheng, Zhuo; Wang, Haipeng; Zhou, Aifeng; Dong, Guanghui; Zhang, Jiawu; Huang, Xiaozhong; Bloemendal, Jan; Rao, Zhiguo
The lack of a precisely-dated, unequivocal climate proxy from northern China, where precipitation variability is traditionally considered as an East Asian summer monsoon (EASM) indicator, impedes our understanding of the behaviour and dynamics of the EASM. Here we present a well-dated, pollen-based, ~20-yr-resolution quantitative precipitation reconstruction (derived using a transfer function) from an alpine lake in North China, which provides for the first time a direct record of EASM evolution since 14.7 ka (ka = thousands of years before present, where the “present” is defined as the year AD 1950). Our record reveals a gradually intensifying monsoon from 14.7–7.0 ka, a maximum monsoon (30% higher precipitation than present) from ~7.8–5.3 ka, and a rapid decline since ~3.3 ka. These insolation-driven EASM trends were punctuated by two millennial-scale weakening events which occurred synchronously to the cold Younger Dryas and at ~9.5–8.5 ka, and by two centennial-scale intervals of enhanced (weakened) monsoon during the Medieval Warm Period (Little Ice Age). Our precipitation reconstruction, consistent with temperature changes but quite different from the prevailing view of EASM evolution, points to strong internal feedback processes driving the EASM, and may aid our understanding of future monsoon behaviour under ongoing anthropogenic climate change. PMID:26084560
Nagatomo, S; Leisman, G
This paper addresses a need to re-examine the mind-body dualism established since Descartes. Descartes' dualism has been regarded by modern philosophers as an extremely insufficient solution to the problem of mind and body, from which is derived a long opposition in modern epistomology between idealism and empiricism. This dualism, bifurcating the region of spirit and matter, and the dichotomous models of thinking based on this dualism, have long dominated the world of modern philosophy and science. The paper examines states of conscious experience from an East Asian perspective allowing analysis on achieved supernormal consciousness rather than a focus on "normal" or "subnormal." The nature of the "transformation" of human consciousness will be studied both philosophically, as a transformation from "provisional" dualism to non-dualism, and neurophysiologically. The theoretical structure of the transformation will, in part, be examined through the model provided by a Japanese medieval Zen master, Takuan Sôhô. Then, to verify Takuan's theoretical explanation, toposcopic analysis of electroencephalographs will be presented of the performance of individuals practicing the martial arts technique of tôate.
Zhang, Yi; Sperber, Kenneth R.; Boyle, James S.
This paper examines the interannual variation of the East Asian winter monsoon and its relationship with EJSO based on the 1979-1995 NCEP/NCAR reanalysis. Two stratifications of cold surges are used. The first one, described as the conventional cold surges, indicates that the surge frequency reaches a urn one year after El Nino events. The second one, originated from the same region as the first, is defined as the maximum wind events near the South China Sea. The variation of this stratification of surges is found to be in good agreement with the South Oscillation Index (SOI). Low SOI (high SOI) events coincide with years of low (high) surge frequency. The interannual variation of averaged meridional wind near the South China Sea and western Pacific is dominated by the South China Sea cold surges, and is also well correlated (R--O.82) with the SOI. Strong wind seasons are associated with La Nina and high SOI events; likewise, weak wind years are linked with El Nino and low SOI cases. This pattern is restricted north of the equator within the region of (OON-20 N, 11OOE-1300E), and is confined to the near surface layer. The surface Siberian high, 500 hPa trough and 200 hPa jetstream, all representing the large-scale monsoon flow, are found to be weaker than normal during El Nino years. In particular, the interannual variation of the Siberian high is in general agreement with the SOL.
Chen, Fahu; Xu, Qinghai; Chen, Jianhui; Birks, H John B; Liu, Jianbao; Zhang, Shengrui; Jin, Liya; An, Chengbang; Telford, Richard J; Cao, Xianyong; Wang, Zongli; Zhang, Xiaojian; Selvaraj, Kandasamy; Lu, Houyuan; Li, Yuecong; Zheng, Zhuo; Wang, Haipeng; Zhou, Aifeng; Dong, Guanghui; Zhang, Jiawu; Huang, Xiaozhong; Bloemendal, Jan; Rao, Zhiguo
The lack of a precisely-dated, unequivocal climate proxy from northern China, where precipitation variability is traditionally considered as an East Asian summer monsoon (EASM) indicator, impedes our understanding of the behaviour and dynamics of the EASM. Here we present a well-dated, pollen-based, ~20-yr-resolution quantitative precipitation reconstruction (derived using a transfer function) from an alpine lake in North China, which provides for the first time a direct record of EASM evolution since 14.7 ka (ka = thousands of years before present, where the "present" is defined as the year AD 1950). Our record reveals a gradually intensifying monsoon from 14.7-7.0 ka, a maximum monsoon (30% higher precipitation than present) from ~7.8-5.3 ka, and a rapid decline since ~3.3 ka. These insolation-driven EASM trends were punctuated by two millennial-scale weakening events which occurred synchronously to the cold Younger Dryas and at ~9.5-8.5 ka, and by two centennial-scale intervals of enhanced (weakened) monsoon during the Medieval Warm Period (Little Ice Age). Our precipitation reconstruction, consistent with temperature changes but quite different from the prevailing view of EASM evolution, points to strong internal feedback processes driving the EASM, and may aid our understanding of future monsoon behaviour under ongoing anthropogenic climate change.
Chen, Fahu; Xu, Qinghai; Chen, Jianhui; Birks, H. John B.; Liu, Jianbao; Zhang, Xiaojian; Jin, Liya
The lack of a precisely-dated, unequivocal climate proxy from northern China, where precipitation variability is traditionally considered as an East Asian summer monsoon (EASM) indicator, impedes our understanding of the behaviour and dynamics of the EASM. Here we present a well-dated, pollen-based, ~20-yr-resolution quantitative precipitation reconstruction (derived using a transfer function) from an alpine lake in North China, which provides for the first time a direct record of EASM evolution since 14.7 ka (ka=thousands of years before present, where the "present" is defined as the year AD 1950). Our record reveals a gradually intensifying monsoon from 14.7-7.0 ka, a maximum monsoon (30% higher precipitation than present) from ~7.8-5.3 ka, and a rapid decline since ~3.3 ka. These insolation-driven EASM trends were punctuated by two millennial-scale weakening events which occurred synchronously to the cold Younger Dryas and at ~9.5-8.5 ka, and by two centennial-scale intervals of enhanced (weakened) monsoon during the Medieval Warm Period (Little Ice Age). Our precipitation reconstruction, consistent with temperature changes but quite different from the prevailing view of EASM evolution, points to strong internal feedback processes driving the EASM, and may aid our understanding of future monsoon behaviour under ongoing anthropogenic climate change.
Jung, Jisun; Horta, Hugo
Studies of higher education by scholars based in Asia have been growing in volume, following worldwide trends. To a large extent, this growth has been driven by East Asian countries, but little is known about the characteristics of the contribution of these countries. This study analyses their overall and specific contribution. The paper concludes…
Regional tendencies in higher education are increasingly important, for example the common rise of North-East Asian universities in China, Hong Kong SAR, Taiwan and South Korea, and Singapore in South-East Asia, to a major global role, following the prior trajectory of Japan. Though the rapidly modernizing Post-Confucian countries do not…
Lau, Kwok Chi
The study has integrated the data from PISA 2006 to 2012 to give an overall picture of the cognitive and affective performances and pedagogy of East Asian regions on PISA scientific literacy. Attempts are made to account for their performances based on the PISA data and cultural characteristics. The cognitive science performance of East Asian…
Little research has been done to investigate the influence of cultural differences on students' second/foreign language learning styles, with a focus on comparing between East and West classroom cultures. This study investigates the differences that East Asian students may encounter when studying in the English-medium academic environment. By…
Wang, J.; Allen, D. J.; Pickering, K. E.; Li, Z.
Three WRF-Chem simulations were conducted for East Asia region during March 2005 East Asian Studies of Tropospheric Aerosols: an International Regional Experiment (EAST-AIRE) Intensive Observation Campaign (IOC) period to investigate the direct effects of aerosols on surface radiation and air quality. WRF-Chem captured the temporal and spatial variations of meteorological fields, trace gases, and aerosol loadings. Surface shortwave radiation changes due to the aerosol direct effect (ADE) were calculated and compared with data from six World Radiation Data Center (WRDC) stations. The comparison indicated that WRF-Chem can simulate the surface short wave radiation moderately well, with temporal correlations between 0.4 and 0.7, and high biases between 9 to 120 W/m2. Domain-wide, WRF-Chem showed a decrease of 22 W/m2 in surface SW radiation due to the aerosol direct effect, consistent with observational studies. The ADE demonstrates diverse influences on air quality in East Asian. For example, the surface concentration of PM2.5 increases in eastern China (~11.1%) due to ADE, but decreases in central China (-7.3%), western China (-8.8%), and Sichuan Basin (-4%). Surface 1-hour maximum ozone is reduced by 2.3%, owing to less radiation reaching the surface due to the ADE. Since PM2.5 pollution raises serious public concern in China, regulations that control the emissions of PM2.5 and its precursors have been implemented. We investigate the impact of reducing two different types of aerosols, sulfate (scattering) and black carbon (absorbing), by cutting 80% of SO2 and black carbon (BC) emissions in two sensitivity simulations. We found that reducing SO2 emissions results in the decline of PM2.5 as much as 16mg/m3 in eastern China, and 20mg/m3 in the Sichuan Basin. Reducing the BC emissions by the same percentage causes the PM2.5 to decrease as much as 40mg/m3 in eastern China, and 25mg/m3 in the Sichuan Basin. The monthly averaged surface 1-hour maximum ozone increases 3
Clift, Peter; Kuhnt, Wolfgang; Wang, Pinxian; Hayes, Dennis
The study of the complex interactions between continents and oceans has become a leading area for 21st century earth cience. In this volume, continent—ocean interactions in tectonics, arc-continent collision, sedimentology, and climatic volution within the East Asian Marginal Seas take precedence. Links between oceanic and continental climate, the sedimentology of coastal and shelf areas, and the links between deformation of continental and oceanic lithosphere are also discussed. As an introduction to the science presented throughout the volume, Wang discusses many of the possible interactions between the tectonic evolution of Asia and both regional and global climate. He speculates that uplift of central Asia in the Pliocene may have triggered the formation of many of the major rivers that drain north through Siberia into the Arctic Ocean. He also argues that it is the delivery of this fresh water that allows the formation of sea ice in that area and triggered the start of Northern Hemispheric glaciation. This may be one of the most dramatic ways in which Asia has shaped the Earth's climate and represents an alternative to the other competing models that have previously emphasized the role of oceanic gateway closure in Central America. Moreover, his proposal for major uplift of at least part of Tibet and Mongolia as late as the Pliocene, based on the history of drainage evolution in Siberia, supports recent data from the southern Tarim Basin and from the Qilian Shan and Qaidam and Jiuxi Basins in northeast Tibet that indicate surface uplift at that time. Constraining the timing and patterns of Tibetan surface uplift is crucial to testing competing models for strain accommodation in Asia following India—Asia collision.
Zhao, G.; Zhang, G.; Wang, Y.; Huang, B.; Dong, Y.; Li, S.; Xiao, W.
Pangea is the youngest supercontinent in Earth's history and its main body formed about 250 million years ago. As supported by voluminous evidence from reliable geological, paleomagnetic and paleontological data, configurations of major continental blocks in Pangea have been widely accepted. However, controversy has long surrounded the reconstructions of East Asian blocks in Pangea. So far, most Pangea reconstructions assume that continental blocks in East Asia had never become parts of Pangea before its breakup. In these reconstruction models, configurations of East Asian blocks in Pangea were mainly based on geological and paleomagnetic data before the 1990's but did not fully consider recent data produced by Chinese researchers about collisional mountain belts between continental blocks in East Asia. To precisely reconstruct the East Asian blocks in Pangea, the Natural Science Foundation of China (NSFC) recently set up a Major NSFC Program entitled 'Reconstruction of East Asian Blocks in Pangea'. On the basis of summarizing and integrating previous data, this major program will carry out detailed field-based structural, metamorphic, geochemical, geochronological, paleomagnetic and paleontonological investigations on key segments of the Central Asian Orogenic Belt, Central China Orogenic Belt and Paleo-Tethys Belt, which assembled major continental blocks in East Asia, in order to determine the timing and processes of opening and closuring of the Paleo-Asian Ocean, Proto-Tethyan Ocean (Qin-Qi-Kun Ocean) and Paleo-Tethyan Ocean. The program will not only answer where, when and how continental blocks in East Asia were assembled and whether or not they had become parts of Pangea before the breakup of the supercontinent, but will also improve and develop the theory of plate tectonics. Acknowledgements: NSFC (41190070, 41190075)
Ahn, Joong-Bae; Lee, Doo-Young; Yoo, Jin‑Ho
Using the retrospective forecasts of seven state-of-the-art coupled models and their multi-model ensemble (MME) for boreal summers, the prediction skills of climate models in the western tropical Pacific (WTP) and East Asian region are assessed. The prediction of summer rainfall anomalies in East Asia is difficult, while the WTP has a strong correlation between model prediction and observation. We focus on developing a new approach to further enhance the seasonal prediction skill for summer rainfall in East Asia and investigate the influence of convective activity in the WTP on East Asian summer rainfall. By analyzing the characteristics of the WTP convection, two distinct patterns associated with El Niño-Southern Oscillation developing and decaying modes are identified. Based on the multiple linear regression method, the East Asia Rainfall Index (EARI) is developed by using the interannual variability of the normalized Maritime continent-WTP Indices (MPIs), as potentially useful predictors for rainfall prediction over East Asia, obtained from the above two main patterns. For East Asian summer rainfall, the EARI has superior performance to the East Asia summer monsoon index or each MPI. Therefore, the regressed rainfall from EARI also shows a strong relationship with the observed East Asian summer rainfall pattern. In addition, we evaluate the prediction skill of the East Asia reconstructed rainfall obtained by hybrid dynamical-statistical approach using the cross-validated EARI from the individual models and their MME. The results show that the rainfalls reconstructed from simulations capture the general features of observed precipitation in East Asia quite well. This study convincingly demonstrates that rainfall prediction skill is considerably improved by using a hybrid dynamical-statistical approach compared to the dynamical forecast alone. Acknowledgements This work was carried out with the support of Rural Development Administration Cooperative Research
Cabezas, Andres F.; Krebes, Kristi; Hussey, Michael M.; Santoni, Brandon G.; Kim, Hyuong Sik
Background The aim of this study was to determine if there were significant differences in glenohumeral joint morphology between North American and East Asian populations that may influence sizing and selection of shoulder arthroplasty systems. Methods Computed tomography reconstructions of 92 North American and 58 East Asian patients were used to perform 3-dimensional measurements. The proximal humeral position was normalized in all patients by aligning it with the scapular plane utilizing anatomic landmarks. Measurements were performed on the humerus and scapula and included coronal and axial humeral head radius, humeral neck shaft and articular arc angles, glenoid height and width, and critical shoulder angle. Glenohumeral relationships were also measured and included lateral distance to the greater tuberosity and acromion, abduction lever arm, and acromial index. Parametric and nonparametric statistical analyses were used to compare population metrics. Results East Asian glenohumeral measurements were significantly smaller for all linear metrics (p < 0.05), with the exception of acromial length, which was greater than in the North American cohort (p < 0.001). The increase in acromial length affected all measurements involving the acromion including abduction lever arms. No difference was found between the neck shaft and articular angular measurements. Conclusions The East Asian population exhibited smaller shoulder morphometrics than their North American cohort, with the exception of an extended acromial overhang. The morphologic data can provide some additional factors to consider when choosing an optimal shoulder implant for the East Asian population, in addition to creating future designs that may better accommodate this population. PMID:27583111
Byun, Soo-yong; Park, Hyunjoon
Using data from the Education Longitudinal Study, this study assessed the relevance of shadow education to the high academic performance of East Asian American students by examining how East Asian American students differed from other racial/ethnic students in the prevalence, purpose, and effects of using the two forms – commercial test preparation service and private one-to-one tutoring – of SAT coaching, defined as the American style of shadow education. East Asian American students were most likely to take a commercial SAT test preparation course for the enrichment purpose, and benefited most from taking this particular form of SAT coaching. However, this was not the case for private SAT one-to-one tutoring. While black students were most likely to utilize private tutoring for the remedial purpose, the impact of private tutoring was trivial for all racial/ethnic groups including East Asian American students. The authors discussed broader implications of the findings on racial/ethnic inequalities in educational achievement beyond the relevance of shadow education for the academic success of East Asian American students. PMID:24163483
Food production in the countries of South and South-East Asia has shown a general upward trend during the last decade. Despite the considerable increase in population in many of these countries, food production per capita in 1988-90 was significantly higher as compared to 1979-81 figures, the increase being specially marked in such countries as Vietnam, Cambodia, Indonesia, and Malaysia. Available daily calorie supply was adequate to meet the requirement. The overall pattern of food production however has shown little change, with cereal production continuing to account for a predominant part of food production. There is no evidence of a significant uptrend with respect to production of pulses, milk, horticultural products, poultry or meat production in most countries. A unique and unfortunate feature of the nutrition situation in South-Asian countries is that the incidence of low birth weight deliveries is as high as 34% (1990), ranging from 25% in Sri Lanka to 50% in Bangladesh (as against less than 7% in the countries of Europe and North America). Even in countries of Africa where the overall food and nutrition situation is worse than in South Asia, the incidence is well below 20%. This is a reflection of the poor state of maternal nutrition in pregnancy. Florid nutritional deficiency diseases have shown a steep decline over the last two decades, but goitre and iron deficiency anaemia continue to be major public health problems, though some headway has been made with regard to the control of the former. Severe forms of growth retardation in children have declined but the majority suffer from mild and moderate forms of growth retardation. Countries of the Region are in varying stages of developmental transition. Among the burgeoning middle classes in some of these countries there are evidences of escalation of degenerative diseases such as diabetes and coronary heart disease. With increasing life expectancy, geriatric nutritional problems will demand increasing
Hsu, Shih-Chieh; Huh, Chih-An; Lin, Chuan-Yao; Chen, Wei-Nai; Mahowald, Natalie M.; Liu, Shaw-Chen; Chou, C. C. K.; Liang, Mao-Chang; Tsai, Chuen-Jinn; Lin, Fei-Jan; Chen, Jen-Ping; Huang, Yi-Tang
It is generally thought that East Asia dominates the supply of eolian dust to the North Pacific. Here we show the first data-based evidence of dust primarily from non-East Asian sources even during March 2010 when a super dust storm from East Asia struck the western Pacific. Chemical characteristics of aerosol samples collected at a high-mountain site in Taiwan show variable inputs from eolian dust and biomass burning. From backward trajectory analyses, satellite observation and model simulation, dust origins can be traced to the Middle East and North Africa, suggesting an integrated source from the global dust belt. Our global model results demonstrate that dust deposition in the North Pacific is primarily contributed by non-East Asian sources with an eastward decrease along the Westerlies.
Parikh, Purvish M.; Raja, T.; Mula-Hussain, L.; Baral, R. P.; Ingle, P.; Narayanan, P.; Tsikai, N.; Baki, M. O.; Satyapal, N.; Adusei, K. O.; Popoola, A.; Musibi, A.; Nyaim, E.; Tsomo, U.; Opio, C.; Jamshed, A.; Reddy, P.
This manuscript captures the discussion and recommendations that came out of a special Afro Asian symposium involving 13 countries. Unmet needs and cost-effective solutions with special emphasis on training form the backbone of practical next steps. PMID:24818109
Lin, B Z; Odahara, S; Ishida, M; Kato, T; Sasazaki, S; Nozawa, K; Mannen, H
The domestic goat is one of the most important livestock species, but its origins and genetic diversity still remain uncertain. Multiple highly divergent maternal lineages of goat have been reported in previous studies. Although one of the mitochondrial DNA lineages, lineage B, was detected only in eastern and southern Asia, the geographic distribution of these lineages was previously unclear. Here, we examine the genetic diversity and phylogeographic structure of Asian goats by mitochondrial DNA sequences and morphological characteristics. The analyses of a total of 1661 Asian goats from 12 countries revealed a high frequency of lineage B in Southeast Asia. The frequency of this lineage tended to be higher in mountain areas than in plain areas in Southeast Asian countries, and there was a significant correlation between its frequency and morphological traits. The results suggest an original predominance of lineage B in Southeast Asia and the recent infiltration of lineage A into Southeast Asian goats.
Hu, Ya; Ding, Qiliang; He, Yungang; Xu, Shuhua; Jin, Li
In this study, we present an analysis of Neanderthal introgression at the dipeptidase 1 gene, DPEP1. A Neanderthal origin for the putative introgressive haplotypes was demonstrated using an established three-step approach. This introgression was under positive natural selection, reached a frequency of >50%, and introduced a homocysteine level- and pigmentation-associated allele (rs460879-T) into East Asians. However, the same allele was also found in non-East Asians, but not from Neanderthal introgression. It is likely that rs460879-T was lost in East Asians and was reintroduced subsequently through Neanderthal introgression. Our findings suggest that Neanderthal introgression could reintroduce an important previously existing allele into populations where the allele had been lost. This study sheds new light on understanding the contribution of Neanderthal introgression to the adaptation of non-Africans.
Stiller, Gabriele; von Clarmann, Thomas; Kellmann, Sylvia; Chirkov, Maksym; Vogel, Bärbel; Müller, Rolf
East-Asian pollution from Southern China or India was shown to be uplifted effectively by the Asian monsoon system to levels just below the tropopause. HCFC-22 nowadays has it strongest source region within East Asia. Due to its long lifetime in the troposphere, it is a very well suited transport tracer. We compare observations from MIPAS/Envisat of HCFC-22 with results from pollution transport modelling by the Lagrangian chemistry-transport model CLaMS. We find that East Asian pollution (and HCFC-22) is uplifted into the Asian monsoon anticyclone at the Eastern flank of the monsoon system. However, we do not find any indication of a significant transport through the tropopause of the Asian monsoon anticyclone into the stratosphere. In contrast, HCFC-22 is transported southwards into the tropics during the end phase and the break-down of the Asian monsoon anticyclone and distributed zonally in the tropics. By this a maximum layer of HCFC-22 just below the tropical tropopause is formed. Further transport into the stratosphere happens mainly by uplift within the upwelling branch of the Brewer-Dobson circulation.
Wang, Jing; Allen, Dale J.; Pickering, Kenneth E.; Li, Zhanqing; He, Hao
WRF-Chem simulations were performed for the March 2005 East Asian Studies of Tropospheric Aerosols: an International Regional Experiment (EAST-AIRE) Intensive Observation Campaign (IOC) to investigate the direct effects of aerosols on surface radiation and air quality. Domain-wide, WRF-Chem showed a decrease of 20 W/m2 in surface shortwave (SW) radiation due to the aerosol direct effect (ADE), consistent with observational studies. The ADE caused 24 h surface PM2.5 (particulate matter with diameter < 2.5 µm) concentrations to increase in eastern China (4.4%), southern China (10%), western China (2.3%), and the Sichuan Basin (9.6%), due to different aerosol compositions in these four regions. Conversely, surface 1 h maximum ozone was reduced by 2.3% domain-wide and up to 12% in eastern China because less radiation reached the surface. We also investigated the impact of reducing SO2 and black carbon (BC) emissions by 80% on aerosol amounts via two sensitivity simulations. Reducing SO2 decreased surface PM2.5 concentrations in the Sichuan Basin and southern China by 5.4% and decreased ozone by up to 6 ppbv in the Sichuan Basin and Southern China. Reducing BC emissions decreased PM2.5 by 3% in eastern China and the Sichuan Basin but increased surface ozone by up to 3.6 ppbv in eastern China and the Sichuan Basin. This study indicates that the benefits of reducing PM2.5 associated with reducing absorbing aerosols may be partially offset by increases in ozone at least for a scenario when NOx and VOC emissions are unchanged.
Huang, Ronghui; Chen, Jilong; Wang, Lin; Lin, Zhongda
Recent advances in the study of the characteristics, processes, and causes of spatio-temporal variabilities of the East Asian monsoon (EAM) system are reviewed in this paper. The understanding of the EAM system has improved in many aspects: the basic characteristics of horizontal and vertical structures, the annual cycle of the East Asian summer monsoon (EASM) system and the East Asian winter monsoon (EAWM) system, the characteristics of the spatio-temporal variabilities of the EASM system and the EAWM system, and especially the multiple modes of the EAM system and their spatio-temporal variabilities. Some new results have also been achieved in understanding the atmosphere-ocean interaction and atmosphere-land interaction processes that affect the variability of the EAM system. Based on recent studies, the EAM system can be seen as more than a circulation system, it can be viewed as an atmosphere-ocean-land coupled system, namely, the EAM climate system. In addition, further progress has been made in diagnosing the internal physical mechanisms of EAM climate system variability, especially regarding the characteristics and properties of the East Asia-Pacific (EAP) teleconnection over East Asia and the North Pacific, the "Silk Road" teleconnection along the westerly jet stream in the upper troposphere over the Asian continent, and the dynamical effects of quasi-stationary planetary wave activity on EAM system variability. At the end of the paper, some scientific problems regarding understanding the EAM system variability are proposed for further study.
Areepattamannil, Shaljan; Caleon, Imelda S.
The authors examined the relationships of cognitive (i.e., memorization and elaboration) and metacognitive learning strategies (i.e., control strategies) to mathematics achievement among 15-year-old students in 4 high-performing East Asian education systems: Shanghai-China, Hong Kong-China, Korea, and Singapore. In all 4 East Asian education…
Chow, Nelson W. S.; Kwan, Alex Y. H.
This report consists of two papers on caregiving in Asian countries. The first, "Caregiving in Developing East and Southeast Asian Countries" by Nelson W. S. Chow, discusses the change in the caregiving pattern for the urban elderly in developing countries of East and Southeast Asia. It includes examples from studies carried out in…
Li, Guofang; Wen, Keying
Drawing on research about East Asian (mainly Chinese, Korean, and Japanese) heritage language (HL) teaching and learning in three contexts--the home, community heritage language schools, and programs in U.S. K-12 schools--this article discusses the challenges that East Asian subethnic groups face in improving HL education in each context.…
Shi, Joy; Grundy, Anne; Richardson, Harriet; Burstyn, Igor; Schuetz, Johanna M; Lohrisch, Caroline A; SenGupta, Sandip K; Lai, Agnes S; Brooks-Wilson, Angela; Spinelli, John J; Aronson, Kristan J
Studies of vitamin D-related genetic variants and breast cancer have been inconsistent. This study aimed to investigate associations of vitamin D-related polymorphisms and breast cancer risk among European and East Asian women and potential interactions with menopausal status and breast tumour subtypes. Data from a case-control study of breast cancer (1037 cases and 1050 controls) were used to assess relationships between 21 polymorphisms in two vitamin D-related genes (GC and VDR) and breast cancer risk. Odds ratios were calculated in stratified analyses of European and East Asian women, using logistic regression in an additive genetic model. An interaction term was used to explore modification by menopausal status. Polytomous regression was used to assess heterogeneity by breast tumour subtype. False discovery rate adjustments were conducted to account for multiple testing. No association was observed between GC or VDR polymorphisms and breast cancer risk. Modification of these relationships by menopausal status was observed for select polymorphisms in both Europeans (VDR rs4328262 and rs11168292) and East Asians (GC rs7041 and VDR rs11168287). Heterogeneity by tumour subtype was seen for three VDR polymorphisms (rs1544410, rs7967152 and rs2239186) among Europeans, in which associations with ER-/PR-/HER2+ tumours, but not with other subtypes, were observed. In conclusion, associations between vitamin D-related genetic variants and breast cancer were not observed overall, although the relationships between vitamin D pathway polymorphisms and breast cancer may be modified by menopausal status and breast tumour subtype.
He, Meian; Xu, Min; Zhang, Ben; Liang, Jun; Chen, Peng; Lee, Jong-Young; Johnson, Todd A.; Li, Huaixing; Yang, Xiaobo; Dai, Juncheng; Liang, Liming; Gui, Lixuan; Qi, Qibin; Huang, Jinyan; Li, Yanping; Adair, Linda S.; Aung, Tin; Cai, Qiuyin; Cheng, Ching-Yu; Cho, Myeong-Chan; Cho, Yoon Shin; Chu, Minjie; Cui, Bin; Gao, Yu-Tang; Go, Min Jin; Gu, Dongfeng; Gu, Weiqiong; Guo, Huan; Hao, Yongchen; Hong, Jie; Hu, Zhibin; Hu, Yanling; Huang, Jianfeng; Hwang, Joo-Yeon; Ikram, Mohammad Kamran; Jin, Guangfu; Kang, Dae-Hee; Khor, Chiea Chuen; Kim, Bong-Jo; Kim, Hung Tae; Kubo, Michiaki; Lee, Jeannette; Lee, Juyoung; Lee, Nanette R.; Li, Ruoying; Li, Jun; Liu, JianJun; Longe, Jirong; Lu, Wei; Lu, Xiangfeng; Miao, Xiaoping; Okada, Yukinori; Ong, Rick Twee-Hee; Qiu, Gaokun; Seielstad, Mark; Sim, Xueling; Song, Huaidong; Takeuchi, Fumihiko; Tanaka, Toshihiro; Taylor, Phil R.; Wang, Laiyuan; Wang, Weiqing; Wang, Yiqin; Wu, Chen; Wu, Ying; Xiang, Yong-Bing; Yamamoto, Ken; Yang, Handong; Liao, Ming; Yokota, Mitsuhiro; Young, Terri; Zhang, Xiaomin; Kato, Norihiro; Wang, Qing K.; Zheng, Wei; Hu, Frank B.; Lin, Dongxin; Shen, Hongbing; Teo, Yik Ying; Mo, Zengnan; Wong, Tien Yin; Lin, Xu; Mohlke, Karen L.; Ning, Guang; Tsunoda, Tatsuhiko; Han, Bok-Ghee; Shu, Xiao-Ou; Tai, E. Shyong; Wu, Tangchun; Qi, Lu
Human height is associated with risk of multiple diseases and is profoundly determined by an individual's genetic makeup and shows a high degree of ethnic heterogeneity. Large-scale genome-wide association (GWA) analyses of adult height in Europeans have identified nearly 180 genetic loci. A recent study showed high replicability of results from Europeans-based GWA studies in Asians; however, population-specific loci may exist due to distinct linkage disequilibrium patterns. We carried out a GWA meta-analysis in 93 926 individuals from East Asia. We identified 98 loci, including 17 novel and 81 previously reported loci, associated with height at P < 5 × 10−8, together explaining 8.89% of phenotypic variance. Among the newly identified variants, 10 are commonly distributed (minor allele frequency, MAF > 5%) in Europeans, with comparable frequencies with in Asians, and 7 single-nucleotide polymorphisms are with low frequency (MAF < 5%) in Europeans. In addition, our data suggest that novel biological pathway such as the protein tyrosine phosphatase family is involved in regulation of height. The findings from this study considerably expand our knowledge of the genetic architecture of human height in Asians. PMID:25429064
Li, Zhanqing; Li, C.; Chen, H.; Tsay, S. C.; Holben, B. N.; Huang, J.; Li, B.; Maring, H.; Qian, Yun; Shi, Guangyu; Xia, X.; Yin, Y.; Zheng, Y.; Zhuang, G.
As the most populated region of the world, Asia is a major source of aerosols with potential large impact over vast downstream areas. Papers published in this special section describe the variety of aerosols observed in China and their effects and interactions with the regional climate as part of the East Asian Study of Tropospheric Aerosols and Impact on Regional Climate (EAST-AIRC). The majority of the papers are based on analyses of observations made under three field projects, namely, the Atmospheric Radiation Measurements (ARM) Mobile Facility mission in China (AMF10 China), the East Asian Study of Tropospheric Aerosols: an International Regional Experiment (EAST-AIRE), and the Atmospheric Aerosols of China and their Climate Effects (AACCE). The former two are US-China collaborative projects and the latter is a part of the China’s National Basic Research program (or often referred to as “973 project”). Routine meteorological data of China are also employed in some studies. The wealth of general and specialized measurements lead to extensive and close-up investigations of the optical, physical and chemical properties of anthropogenic, natural, and mixed aerosols; their sources, formation and transport mechanisms; horizontal, vertical and temporal variations; direct and indirect effects and interactions with the East Asian monsoon system. Particular efforts are made to advance our understanding of the mixing and interaction between dust and anthropogenic pollutants during transport. Several modeling studies were carried out to simulate aerosol impact on radiation budget, temperature, precipitation, wind and atmospheric circulation, fog, etc. In addition, impacts of the Asian monsoon system on aerosol loading are also simulated.
Onishi, Chie; Ikejiri, Fumiyoshi; Kawakami, Koshi; Miyake, Takaaki; Kumanomido, Satoshi; Inoue, Masaya; Takahashi, Tsutomu; Tanaka, Junko; Yamamoto, Masahiro; Sugimoto, Toshitsugu; Suzumiya, Junji
The Asian variant of intravascular large B cell lymphoma is a special type of intravascular lymphoma with hemophagocytic syndrome and hypercytokinemia including interleukin-6, which stimulates antidiuretic hormone synthesis in the hypothalamus. We present here that the syndrome of inappropriate antidiuretic hormone secretion frequently occurs in patients with the Asian variant of intravascular large B cell lymphoma. The syndrome of inappropriate antidiuretic hormone secretion was found in eight of 118 (6.8%) lymphoma patients at the first diagnosis. Although there were six (5.1%) among 118 lymphoma patients with the Asian variant of intravascular large B cell lymphoma, four of the six patients (66.7%) developed the syndrome of inappropriate antidiuretic hormone secretion. In four patients with the Asian variant of intravascular large B cell lymphoma with the syndrome of inappropriate antidiuretic hormone secretion, elevated serum interleukin-6 and low sodium levels were almost normalized after chemotherapy. The Asian variant of intravascular large B cell lymphoma patients frequently develop the syndrome of inappropriate antidiuretic hormone secretion, and interleukin-6 might play a role in the occurrence of this disease. We should pay attention to hyponatremia caused by the syndrome of inappropriate antidiuretic hormone secretion in patients with the Asian variant of intravascular large B cell lymphoma.
Hsu, S.; Huh, C.; Lin, C.; Chen, W.; Mahowald, N. M.; Liu, S. C.; Chou, C. C.; Liang, M.; Tsai, C.; Lin, F.; Chen, J.; Huang, Y.
It is generally thought that East Asia dominates the supply of eolian dust to the North Pacific. Here we show the first data-based evidence of dust primarily from non-East Asian sources even during March 2010 when a super dust storm from East Asia struck the western Pacific. Chemical characteristics of aerosol samples collected at a high-mountain site in Taiwan show variable inputs from eolian dust and biomass burning. From backward trajectory analyses, satellite observation and model simulation, dust origins can be traced to the Middle East and North Africa, suggesting an integrated source from the global dust belt. Our global model results demonstrate that dust deposition in the North Pacific is primarily contributed by non-East Asian sources with an eastward decrease along the Westerlies. Time-series of aerosol composition at Mt. Lulin: (A) 210Pb and biomass burning potassium (KBB), (B) 7Be and aluminum. Also shown (in A) are daily mean O3 and CO , hourly relative humidity (gray curve/area) and (in B) daily rainfall (yellow bars) measured at Taiwan EPA's Lulin Atmospheric Background Station (LABS), ~25 m southeast of our aerosol sampling site. Results from the MATCH model showing (A) total annual dust deposition fluxes, and (B) fraction of the total deposition attributable to East Asian sources over the North Pacific.
Zhou, Xin; Sun, Liguang; Chu, Yangxi; Xia, Zehui; Zhou, Xinying; Li, Xiangzhong; Chu, Zhuding; Liu, Xiangjun; Shao, Da; Wang, Yuhong
Heinrich event 1 (H1) is an important millennial climate event during the last deglaciation. The substantial decreasing of monsoon strength in the East Asian monsoon region during the H1, as shown by stalagmite δ18O records, has been attributed to the southward shift of the intertropical convergence zone (ITCZ), which is caused by the slowdown/collapse of the Atlantic meridional overturning circulation (AMOC). However, records from different Asian monsoon regions show various trends in precipitation changes during the H1, and these trends cannot be solely interpreted by the southward shift of the ITCZ. In the present study, we reconstructed time-series of East Asian monsoon precipitation between 25,000 and 10,000 a BP from floodplain sediments in the Huai River Basin. A white sediment layer, distinct from other layers in the profile, contains significantly low TOC, tree pollen and fern spore contents, and more positive δ13Corg, and it is deposited during the H1 event. The determined TOC, pollen and δ13Corg time-series, together with previously reported stalagmite δ18O, indicate a catastrophic (severe) drought in Jianghuai Region, one of the East Asian monsoon regions, during the H1. The La Niña condition in tropical Pacific likely also contributes to the catastrophic drought in Jianghuai Region and the precipitation variations in the Asian monsoon region during the H1.
Hao, Nan; Ding, Aijun; Safieddine, Sarah; Valks, Pieter; Clerbaux, Cathy; Trautmann, Thomas
Air pollution is one of the most important environmental problems in developing Asian countries like China. In this region, studies showed that the East Asian monsoon plays a significant role in characterizing the temporal variation and spatial patterns of air pollution, since monsoon is a major atmospheric system affecting air mass transport, convection, and precipitation. Knowledge gaps still exist in the understanding of Asian monsoon impact on the air quality in China under the background of global climate change. For the first time satellite observations of tropospheric ozone and its precursors will be integrated with the ground-based, aircraft measurements of air pollutants and model simulations to study the impact of the East Asian monsoon on air quality in China. We apply multi-platform satellite observations by the GOME-2, IASI, and MOPITT instruments to analyze tropospheric ozone and CO, precursors of ozone (NO2, HCHO and CHOCHO) and other related trace gases over China. Two years measurements of air pollutants including NO2, HONO, SO2, HCHO and CHOCHO at a regional back-ground site in the western part of the Yangtze River Delta (YRD) in eastern China will be presented. The potential of using the current generation of satellite instruments, ground-based instruments and aircraft to monitor air quality changes caused by the East Asian monsoon circulation will be presented. Preliminary comparison results between satellite measurement and limited but valuable ground-based and aircraft measurements will also be showed.
Lee, Boram; Farruggia, Susan P.; Brown, Gavin T. L.
The study focused on learning difficulties experienced by East Asian International (EAI) students. Participants were 117 EAI students undertaking tertiary study at a major university, all were surveyed and 21 students were interviewed. The findings suggest that language limitations, academic content and learning styles were associated with…
Li, Jiaqi; Wang, Yanlin; Xiao, Feiya
The present article reports a systematic review of the studies related to psychological well-being among East Asian international students. A total of 18 quantitative studies published in peer-reviewed journals from 2000 to 2011 were reviewed. Our review revealed three major results: (1) a majority of researchers (n = 13, 72.2%) tend to choose…
Chen, Rainbow Tsai-Hung
Many East-Asian countries are actively positioning themselves as receiving countries of international students. Consequently, the number of international students in these countries is steadily growing. Given the differences between Eastern and Western conceptions of teaching and learning, it could be expected that Western learners studying in the…
The author argues that there is an ongoing debate among educators concerning the extent to which American educators can learn from East Asian school systems. Some social scientists argue that cultural differences make this impossible. Others argue that there are many ways that Americans can benefit. The author believes that both sides of this…
Lin, Yi-Jiun; Flores, Lisa Y.
Using a sample of 86 East Asian international graduate students, this study examined Bandura's perceived self-efficacy model (1986) in the domain of job search self-efficacy and tested the mediating effects of job search self-efficacy in the relationship between efficacy source variables and job search behaviors. Results show that both performance…
Morton, Heather; Gorzalka, Boris B
The purpose of this study was to investigate the sexual beliefs of female undergraduates, as well as the thoughts they experience during sexual experiences. The study aimed to determine potential differences in these variables between East Asian-Canadians and Euro-Canadians, as well as the influence of acculturation on these variables. In addition, the relationships between sexual beliefs, automatic thoughts, and specific aspects of sexual functioning were examined. Euro-Canadian (n = 77) and East Asian-Canadian (n = 123) undergraduate women completed the Sexual Dysfunctional Beliefs Questionnaire, the Sexual Modes Questionnaire, the Female Sexual Function Index, and the Vancouver Index of Acculturation. East Asian women endorsed almost all sexual beliefs assessed in this study more than did Euro-Canadian women, and endorsement of these beliefs was associated with acculturation. In addition, East Asian-Canadian and Euro-Canadian women differed in the frequency of experiencing negative automatic thoughts. Results also revealed associations between difficulties in sexual functioning, and both sexual beliefs and automatic thoughts. Together, these results provide preliminary support for the hypothesis that differences in cognitive aspects of sexuality may underlie the differences in sexual functioning previously observed between these two groups.
Woo, Jane S T; Brotto, Lori A; Yule, Morag A
Evidence from studies of ethnic differences in sexual conservativeness and Papanicolaou (Pap) testing behaviors suggests that there may be culture-linked differences in rates of participation in physically invasive sexuality studies, resulting in volunteer bias. The effects of ethnicity and acculturation on participation in female psychophysiological sexual arousal research were investigated in a sample of Euro-Canadian (n = 50) and East Asian (n = 58) women. Participants completed a battery of questionnaires and were given either course credits or $10 for their participation. Participants were then informed about the opportunity to participate in a second phase of the study, which involved psychophysiological sexual arousal testing and which was completely optional. Contrary to expectations, the results showed that the East Asian women were more likely to participate in Phase 2 than the Euro-Canadian women. Among the East Asian women, greater heritage acculturation and lower mainstream acculturation predicted a lower likelihood of Phase 2 participation. The findings suggest the need to be wary of overgeneralizing female psychophysiological sexual arousal research results and may have implications for improving Pap testing behaviors in East Asian women.
Lang, LingLing; Irby, Beverly J.; Brown, Genevieve
For more than 2000 years, Confucian teaching has had tremendous influence on the history, politics, economy, and culture of East Asian countries and regions. Despite the rapid growth in gross domestic product (GDP), people's standard of living, and economic advancements, Confucian Asia continues to adhere to the Confucian cultural values that they…
Smits, Jeroen; Park, Hyunjoon
We study trends in educational homogamy at six boundaries in the educational structure of 10 East-Asian societies and explain its variation using explanatory variables at the country, cohort and boundary level. Educational homogamy was higher at the higher boundaries in the educational structure. Since the 1950s it decreased at all but the lowest…
Kitao, S. Kathleen
A study of the relationship of request comprehension with context and experience with the language is reported. Sixty-two East Asian non-native English speaking students from China, Japan, South Korea, and Taiwan were presented with seemingly spontaneous indirect requests during a taped interview. Their ability to respond appropriately to the…
Yokogawa, Kōji; Watanabe, Ken-Ichi; Ogihara, Gota
Because of the taxonomic confusion, including misapplication of their scientific names, resulting from the morphological similarity of two East Asian flatfish species, Pleuronichthys lighti Wu, 1929 and Pleuronichthys cornutus (Temminck & Schlegel, 1846), both species are redescribed, with particular emphasis on some new key characters. New common names are proposed for each species.
Seo, Dong-Chul; Torabi, Mohammad R.; Chin, Ming-Kai; Lee, Chung Gun; Kim, Nayoung; Huang, Sen-Fang; Chen, Chee Keong; Mok, Magdalena Mo Ching; Wong, Patricia; Chia, Michael; Park, Bock-Hee
Objective: To identify levels of moderate-intensity physical activity (MPA) and vigorous-intensity physical activity (VPA) in a representative sample of college students in six East Asian economies and examine their relationship with weight, alcohol consumption and cigarette smoking. Design: Cross-sectional survey. Setting: College students…
Zacharias, Nugrahenny Tourisia
This study reports the evolving teacher identities of 12 South/East Asian teachers during their study in the United States. Grounded in poststructuralist views of identities, the study employed narrative analysis to capture the complexities of teacher identity construction. Narrative data were collected through in-depth individual interviews,…
Jeong, Yu-Jin; Acock, Alan C.
Drawing on the National Educational Longitudinal Survey 1988 (NELS:88), this study identified (1) the growth pattern of academic achievement of adolescent children from Mexican and East Asian immigrant families; (2) investigated to what extent ethnicity and family capital influenced the trajectories in the academic achievement of children from…
Yang, Jean Sook Ryu
College Students enrolled in East Asian language classes were surveyed about their language learning motivational orientations (MOs). MOs were classified and measured on seven subscales; integrative, instrumental, heritage-related, travel, interest, school-related, and language use. Learners were highly influenced by interest, language use, and…
This article relates changes in higher education (HE) and research in East Asian societies to recent trends in political economy and, in particular, the reorientation of developmental states (DSs) in the region. The DS is oriented to catch-up competitiveness and, as the horizon of development shifts, so do its appropriate institutional forms and…
The present study examined roles that perceived English fluency and sociocultural adaptation difficulty play in predicting self-efficacy beliefs for teaching in a sample of 119 international teaching assistants (ITAs) from East Asian countries of China, Japan, Korea and Taiwan. Results showed that a positive relationship between perceived English…
Purpose: The purpose of this paper is to provide a structural overview about indigenous approaches to learning in South East Asian countries, with a particular reference to education initiatives that have been operating in this region; and especially to investigate information and communication technologies (ICT) systems, in combination with…
Lu, Chunhui; Zhou, Botao; Ding, Yihui
We analyze the decadal variation of the stratosphere-troposphere coupled system around the year 2000 by using the NCEP reanalysis-2 data. Specifically, the relationship between the Northern Hemisphere Annular Mode (NAM) and the tropospheric East Asian trough is investigated in order to find the effective stratospheric signals during cold air outbreaks in China. Statistical analyses and dynamic diagnoses both indicate that after 2000, increased stratospheric polar vortex disturbances occur and the NAM is mainly in negative phase. The tropospheric polar areas are directly affected by the polar vortex, and in the midlatitudes, the Ural blocking high and East Asian trough are more active, which lead to enhanced cold air activities in eastern and northern China. Further investigation reveals that under this circulation pattern, downward propagations of negative NAM index are closely related to the intensity variation of the East Asian trough. When negative NAM anomalies propagate down to the upper troposphere and reach a certain intensity (standardized NAM index less than-1), they result in apparent reinforcement of the East Asian trough, which reaches its maximum intensity about one week later. The northerly wind behind the trough transports cold air southward and eastward, and the range of influence and the intensity are closely associated with the trough location. Therefore, the NAM index can be used as a measure of the signals from the disturbed stratosphere to give some indication of cold air activities in China.
Hien, P. D.
This paper presents a comparative study of research performance of 11 East and Southeast Asian countries based upon the total number of peer-refereed international publications (PRIP) per one million people (research intensity), the mean citation, and the contribution of domestic authors in PRIP production. Large gaps are observed within the…
Sun, Celi; Molineros, Julio E.; Looger, Loren L.; Zhou, Xu-jie; Kim, Kwangwoo; Okada, Yukinori; Ma, Jianyang; Qi, Yuan-yuan; Kim-Howard, Xana; Motghare, Prasenjeet; Bhattarai, Krishna; Adler, Adam; Bang, So-Young; Lee, Hye-Soon; Kim, Tae-Hwan; Kang, Young Mo; Suh, Chang-Hee; Chung, Won Tae; Park, Yong-Beom; Choe, Jung-Yoon; Shim, Seung Cheol; Kochi, Yuta; Suzuki, Akari; Kubo, Michiaki; Sumida, Takayuki; Yamamoto, Kazuhiko; Lee, Shin-Seok; Kim, Young Jin; Han, Bok-Ghee; Dozmorov, Mikhail; Kaufman, Kenneth M.; Wren, Jonathan D.; Harley, John B.; Shen, Nan; Chua, Kek Heng; Zhang, Hong; Bae, Sang-Cheol; Nath, Swapan K.
Systemic lupus erythematosus (SLE) has a strong but incompletely understood genetic architecture. We conducted an association study with replication in 4,492 SLE cases and 12,675 controls from six East-Asian cohorts, to identify novel and better localize known SLE susceptibility loci. We identified 10 novel loci as well as 20 known loci with genome-wide significance. Among the novel loci, the most significant was GTF2IRD1-GTF2I at 7q11.23 (rs73366469, Pmeta=3.75×10−117, OR=2.38), followed by DEF6, IL12B, TCF7, TERT, CD226, PCNXL3, RASGRP1, SYNGR1 and SIGLEC6. We localized the most likely functional variants for each locus by analyzing epigenetic marks and gene regulation data. Ten putative variants are known to alter cis- or trans-gene expression. Enrichment analysis highlights the importance of these loci in B- and T-cell biology. Together with previously known loci, the explained heritability of SLE increases to 24%. Novel loci share functional and ontological characteristics with previously reported loci, and are possible drug targets for SLE therapeutics. PMID:26808113
Sun, Celi; Molineros, Julio E; Looger, Loren L; Zhou, Xu-Jie; Kim, Kwangwoo; Okada, Yukinori; Ma, Jianyang; Qi, Yuan-Yuan; Kim-Howard, Xana; Motghare, Prasenjeet; Bhattarai, Krishna; Adler, Adam; Bang, So-Young; Lee, Hye-Soon; Kim, Tae-Hwan; Kang, Young Mo; Suh, Chang-Hee; Chung, Won Tae; Park, Yong-Beom; Choe, Jung-Yoon; Shim, Seung Cheol; Kochi, Yuta; Suzuki, Akari; Kubo, Michiaki; Sumida, Takayuki; Yamamoto, Kazuhiko; Lee, Shin-Seok; Kim, Young Jin; Han, Bok-Ghee; Dozmorov, Mikhail; Kaufman, Kenneth M; Wren, Jonathan D; Harley, John B; Shen, Nan; Chua, Kek Heng; Zhang, Hong; Bae, Sang-Cheol; Nath, Swapan K
Systemic lupus erythematosus (SLE) has a strong but incompletely understood genetic architecture. We conducted an association study with replication in 4,478 SLE cases and 12,656 controls from six East Asian cohorts to identify new SLE susceptibility loci and better localize known loci. We identified ten new loci and confirmed 20 known loci with genome-wide significance. Among the new loci, the most significant locus was GTF2IRD1-GTF2I at 7q11.23 (rs73366469, Pmeta = 3.75 × 10(-117), odds ratio (OR) = 2.38), followed by DEF6, IL12B, TCF7, TERT, CD226, PCNXL3, RASGRP1, SYNGR1 and SIGLEC6. We identified the most likely functional variants at each locus by analyzing epigenetic marks and gene expression data. Ten candidate variants are known to alter gene expression in cis or in trans. Enrichment analysis highlights the importance of these loci in B cell and T cell biology. The new loci, together with previously known loci, increase the explained heritability of SLE to 24%. The new loci share functional and ontological characteristics with previously reported loci and are possible drug targets for SLE therapeutics.
Lee, D. Y.; Ahn, J. B.; Yoo, J. H.
The prediction skills of climate model simulations in the western tropical Pacific (WTP) and East Asian region are assessed using the retrospective forecasts of seven state-of-the-art coupled models and their multi-model ensemble (MME) for boreal summers (June-August) during the period 1983-2005, along with corresponding observed and reanalyzed data. The prediction of summer rainfall anomalies in East Asia is difficult, while the WTP has a strong correlation between model prediction and observation. We focus on developing a new approach to further enhance the seasonal prediction skill for summer rainfall in East Asia and investigate the influence of convective activity in the WTP on East Asian summer rainfall. By analyzing the characteristics of the WTP convection, two distinct patterns associated with El Niño-Southern Oscillation (ENSO) developing and decaying modes are identified. Based on the multiple linear regression method, the East Asia Rainfall Index (EARI) is developed by using the interannual variability of the normalized Maritime continent-WTP indices (MPIs), as potentially useful predictors for rainfall prediction over East Asia, obtained from the above two main patterns. For East Asian summer rainfall, the EARI has superior performance to the East Asia summer monsoon index (EASMI) or each MP index (MPI). Therefore, the regressed rainfall from EARI also shows a strong relationship with the observed East Asian summer rainfall pattern. In addition, we evaluate the prediction skill of the East Asia reconstructed rainfall obtained by statistical-empirical approach using the cross-validated EARI from the individual models and their MME. The results show that the rainfalls reconstructed from simulations capture the general features of observed precipitation in East Asia quite well. This study convincingly demonstrates that rainfall prediction skill is considerably improved by using the statistical-empirical method compared to the dynamical models
This study seeks to explain why and how international graduate students from East Asia choose to come to Canada to pursue advanced education, to assess the strengths and dynamics of the factors influencing the enrollment decision, and to describe possible implications both for education-exporting countries and universities offering graduate…
Yu, Guirui; Chen, Zhi; Piao, Shilong; Peng, Changhui; Ciais, Philippe; Wang, Qiufeng; Li, Xuanran; Zhu, Xianjin
Temperate- and high-latitude forests have been shown to contribute a carbon sink in the Northern Hemisphere, but fewer studies have addressed the carbon balance of the subtropical forests. In the present study, we integrated eddy covariance observations established in the 1990s and 2000s to show that East Asian monsoon subtropical forests between 20 °N and 40 °N represent an average net ecosystem productivity (NEP) of 362 ± 39 g C m(-2) yr(-1) (mean ± 1 SE). This average forest NEP value is higher than that of Asian tropical and temperate forests and is also higher than that of forests at the same latitudes in Europe-Africa and North America. East Asian monsoon subtropical forests have comparable NEP to that of subtropical forests of the southeastern United States and intensively managed Western European forests. The total NEP of East Asian monsoon subtropical forests was estimated to be 0.72 ± 0.08 Pg C yr(-1), which accounts for 8% of the global forest NEP. This result indicates that the role of subtropical forests in the current global carbon cycle cannot be ignored and that the regional distributions of the Northern Hemisphere's terrestrial carbon sinks are needed to be reevaluated. The young stand ages and high nitrogen deposition, coupled with sufficient and synchronous water and heat availability, may be the primary reasons for the high NEP of this region, and further studies are needed to quantify the contribution of each underlying factor.
Yu, Guirui; Chen, Zhi; Piao, Shilong; Peng, Changhui; Ciais, Philippe; Wang, Qiufeng; Li, Xuanran; Zhu, Xianjin
Temperate- and high-latitude forests have been shown to contribute a carbon sink in the Northern Hemisphere, but fewer studies have addressed the carbon balance of the subtropical forests. In the present study, we integrated eddy covariance observations established in the 1990s and 2000s to show that East Asian monsoon subtropical forests between 20°N and 40°N represent an average net ecosystem productivity (NEP) of 362 ± 39 g C m−2 yr−1 (mean ± 1 SE). This average forest NEP value is higher than that of Asian tropical and temperate forests and is also higher than that of forests at the same latitudes in Europe–Africa and North America. East Asian monsoon subtropical forests have comparable NEP to that of subtropical forests of the southeastern United States and intensively managed Western European forests. The total NEP of East Asian monsoon subtropical forests was estimated to be 0.72 ± 0.08 Pg C yr−1, which accounts for 8% of the global forest NEP. This result indicates that the role of subtropical forests in the current global carbon cycle cannot be ignored and that the regional distributions of the Northern Hemisphere's terrestrial carbon sinks are needed to be reevaluated. The young stand ages and high nitrogen deposition, coupled with sufficient and synchronous water and heat availability, may be the primary reasons for the high NEP of this region, and further studies are needed to quantify the contribution of each underlying factor. PMID:24639529
Ng, Joseph Soon-Yau; Ismail-Pratt, Ida
The Association of Southeast Asian Nations (ASEAN) is a confederation of 10 sovereign states occupying approximately 1.7 million square miles of Southeast Asia with an estimated population of just under 630 million. Southeast Asia continues to have one of the world's highest rates of cervical cancer-related death. Organised training in cervical cancer screening is essential but lacking in low to middle income countries (LMICs). Systematic training of local doctors is an essential part of an effective screening program and an effective strategy to reduce cervical cancer-related mortality. Singapore is a first-world economy with a healthcare system that can support this mode of training and is geographically proximate to Southeast Asian LMICs that need this training. This makes it possible for model of tiered training with trainers on site in the LMICs and more advanced training where trainees receive training in Singapore. We present a case study where this tiered system of training is applied to Cambodia and demonstrate that this model of training is not only effective but also sustainable.
Seino, Yutaka; Kuwata, Hitoshi; Yabe, Daisuke
Type 2 diabetes in East Asians is characterized primarily by β-cell dysfunction, and with less adiposity and less insulin resistance compared with that in Caucasians. Such pathophysiological differences can determine the appropriate therapeutics for the disease. Incretins, glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1, are secreted in response to meal ingestion, and enhance insulin secretion glucose-dependently. Incretin-based drugs, dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists, that ameliorate β-cell dysfunction with limited hypoglycemia risk are now widely used in type 2 diabetes management. Recent meta-analyses of clinical trials on DPP-4i and glucagon-like peptide-1 receptor agonists found that the drugs were more effective in Asians, most likely because of amelioration of β-cell dysfunction. In addition, we found increased glycated hemoglobin-lowering effects of DPP-4i to be associated with intake of fish in type 2 diabetes, which suggests that dietary customs of East Asians might also underlie the greater efficacy of DPP-4i. Despite the limited risk, cases of severe hypoglycemia were reported for DPP-4i/sulfonylureas combinations. Importantly, hypoglycemia was more frequent in patients also receiving glibenclamide or glimepiride, which activate exchange protein directly activated by cyclic adenosine monophosphate 2, a critical mediator of incretin signaling, and was less frequent in patients receiving gliclazide, which does not activate exchange protein directly activated by cyclic adenosine monophosphate 2. Prevention of insulin-associated hypoglycemia by DPP-4i has gained attention with regard to the enhancement of hypoglycemia-induced glucagon secretion by insulinotropic polypeptide, but remains to be investigated in East Asians. Despite the safety issues, which are paramount and must be carefully monitored, the incretin-based drugs could have potential as a first choice therapy in
Kim, Bernard Y; Lohmueller, Kirk E
It has been hypothesized that the greater proportion of Neandertal ancestry in East Asians than in Europeans is due to the fact that purifying selection is less effective at removing weakly deleterious Neandertal alleles from East Asian populations. Using simulations of a broad range of models of selection and demography, we have shown that this hypothesis cannot account for the higher proportion of Neandertal ancestry in East Asians than in Europeans. Instead, more complex demographic scenarios, most likely involving multiple pulses of Neandertal admixture, are required to explain the data.
Ji, Linong; Min, Kyung Wan; Oliveira, Juliana; Lew, Thomas; Duan, Ran
Objective The objective of this study was to explore the efficacy and safety of insulin lispro mix 25 (25% insulin lispro and 75% insulin lispro protamine suspension [LM25]) or insulin glargine plus insulin lispro (G+L) in insulin-naïve patients with type 2 diabetes from different racial/ethnic groups. Methods Three subgroups from the PARADIGM study were analyzed post hoc: non-Asian (n=130), Asian Indian (n=106), and East Asian (n=89). Results All subgroups recorded glycated hemoglobin (HbA1c) reductions: non-Asian (LM25, −2.07%; G+L, −2.05%), Asian Indian (LM25, −1.75%; G+L, −1.60%), and East Asian (LM25, −2.03%; G+L, −1.76%); end point HbA1c values were higher in Asian Indians and East Asians than in non-Asians. Fewer Asian Indians (LM25, 43.2%; G+L, 29.2%) and East Asians (LM25, 37.5%; G+L, 36.1%) reached HbA1c <7% versus non-Asians (LM25, 51.7%; G+L, 48.1%); differences were not significant (P=0.12 and P=0.06, respectively). The mean total daily insulin dose (U/kg) for non-Asians was 0.67 (LM25) and 0.61 (G+L), for Asian Indians was 0.91 (LM25) and 0.90 (G+L), and for East Asians was 0.53 (LM25) and 0.59 (G+L). The ratio of mealtime to total insulin dose in the G+L arm for non-Asians was 0.19±0.23, for Asian Indians was 0.33±0.25, and for East Asians was 0.34±0.27. Overall incidence (%) of hypoglycemia in non-Asians was 94.1 (LM25) and 91.8 (G+L), in Asian Indians was 90.4 (LM25) and 88.5 (G+L), and in East Asians was 69.8 (LM25) and 77.3 (G+L). Conclusion Asian Indians showed least improvement in glycemic HbA1c reduction despite greater insulin use. East Asians and non-Asians achieved similar HbA1c reduction in the LM25 arm with a lower rate of hypoglycemia. Asians required more mealtime insulin coverage than non-Asians. This study added important insight into the effect of ethnicity on insulin treatment outcomes in patients with type 2 diabetes. PMID:27563254
The incidence of cutaneous melanoma (CM) has rapidly increased over the past four decades. CM is often overlooked in East Asian populations due to its low incidence, despite East Asia making up 22% of the world’s population. Since the 1990s, Caucasian populations have seen a plateau in CM mortality rates; however, there is little data investigating the mortality rates of CM in East Asian populations. In this study, the World Health Organization Mortality Database with the joinpoint regression method, and a generalized additive model were used to investigate trends in age standardized mortality rates (ASMRs) of CM in four East Asia regions (Japan, Republic of Korea (Korea), China: Hong Kong (Hong Kong), and Singapore) over the past six decades. In addition, mortality rate ratios by different variables (i.e., sex, age group, and region) were analyzed. Our results showed ASMRs of CM in East Asia significantly increased non-linearly over the past six decades. The joinpoint regression method indicated women had greater annual percentage changes than men in Japan, Korea, and Hong Kong. Men had significantly greater mortality rate ratio (1.51, 95% CI [1.48–1.54]) than women. Mortality rate ratios in 30−59 and 60+ years were significant greater than in the 0−29 years. Compared to Hong Kong, mortality rate ratio was 0.72 (95% CI [0.70–0.74]) times, 0.73 (95% CI [0.70–0.75]) times, and 1.02 (95% CI [1.00–1.05]) times greater in Japan, Korea, and Singapore, respectively. Although there is limited research investigating CM mortality rates in East Asia, results from the present study indicate that there is a significant growth in the ASMRs of CM in East Asian populations, highlighting a need to raise awareness of CM in the general population. PMID:28028475
Chen, Ling; Jin, Shaofei
The incidence of cutaneous melanoma (CM) has rapidly increased over the past four decades. CM is often overlooked in East Asian populations due to its low incidence, despite East Asia making up 22% of the world's population. Since the 1990s, Caucasian populations have seen a plateau in CM mortality rates; however, there is little data investigating the mortality rates of CM in East Asian populations. In this study, the World Health Organization Mortality Database with the joinpoint regression method, and a generalized additive model were used to investigate trends in age standardized mortality rates (ASMRs) of CM in four East Asia regions (Japan, Republic of Korea (Korea), China: Hong Kong (Hong Kong), and Singapore) over the past six decades. In addition, mortality rate ratios by different variables (i.e., sex, age group, and region) were analyzed. Our results showed ASMRs of CM in East Asia significantly increased non-linearly over the past six decades. The joinpoint regression method indicated women had greater annual percentage changes than men in Japan, Korea, and Hong Kong. Men had significantly greater mortality rate ratio (1.51, 95% CI [1.48-1.54]) than women. Mortality rate ratios in 30-59 and 60+ years were significant greater than in the 0-29 years. Compared to Hong Kong, mortality rate ratio was 0.72 (95% CI [0.70-0.74]) times, 0.73 (95% CI [0.70-0.75]) times, and 1.02 (95% CI [1.00-1.05]) times greater in Japan, Korea, and Singapore, respectively. Although there is limited research investigating CM mortality rates in East Asia, results from the present study indicate that there is a significant growth in the ASMRs of CM in East Asian populations, highlighting a need to raise awareness of CM in the general population.
Yamaoka, Y; Osato, M S; Sepulveda, A R; Gutierrez, O; Figura, N; Kim, J G; Kodama, T; Kashima, K; Graham, D Y
The predominant H. pylori strain circulating among geographic locations differs with regard to the genomic structure. This study determined whether structural subtypes of the cagA 3' repeat region could be used to identify the population of origin of H. pylori isolates. We examined 600 cagA-positive H. pylori (Colombia, 100; USA, 100; France, 100; Canada, 20; Italy, 20; Korea, 100; Japan, 100; Hong Kong, 20; Taiwan, 20; Vietnam, 20). The cagA 3' region was amplified by PCR using primers specific to Japanese and Western 3' cagA gene sequences. PCR using Japanese cagA primers resulted in PCR products in 99-6 % of strains from East Asia but no non-Asian strains. Conversely, PCR using Western cagA primers resulted in amplicons in 100% of non-Asian strains, and only one from East Asia. cagA genotyping is useful for molecular epidemiological studies as strains can be completely separated by differences in the cagA 3' region.
Zhou, Xin; Sun, Liguang; Zhan, Tao; Huang, Wen; Zhou, Xinying; Hao, Qingzhen; Wang, Yuhong; He, Xiaoqing; Zhao, Chao; Zhang, Jun; Qiao, Yansong; Ge, Junyi; Yan, Pei; Yan, Qing; Shao, Da; Chu, Zhuding; Yang, Wenqing; Smol, John P.
The East Asian summer monsoon affects precipitation and hence vegetation in the densely populated Northwest Pacific region, yet a long-standing controversy exists concerning the spatial and temporal dynamics of the Holocene Optimum (HO) in the East Asian Monsoon Region. Here we use a detailed 14,000-year record reconstructing vegetation variations from a strategically selected crater lake from Northeast China, as well as a compilation of previous paleoclimatic studies, to show that the HO began around 6,000 Cal a BP in Northeast China, significantly later than generally recognized. By comparing our paleoenvironmental data with Holocene vegetation records from other regions of East Asia, we identified a marked northward shift for the onset of the HO from ∼ 10 , 260 Cal a BP in South China to ∼ 6 , 000 Cal a BP in Northeast China. The gradual northward transgression of the vegetation change could be caused by both the temperature and precipitation changes in different regions. Finally, we fitted a regression model of the start of the HO period versus latitude, which allowed us to make predictions for the beginning of the HO at different geographical locations. This study reveals a strong relationship between latitude and the initiation of the HO, and provides a window towards better understanding the forcing of vegetation changes in the East Asian monsoon region.
de Grijs, Richard
At the 2012 General Assembly of the International Astronomical Union (IAU), the Office of Astronomy for Development (OAD) programme announced a number of exciting new partnerships to assist with the IAU's decadal strategic plan (2010-2020). These landmark decisions included establishing a new coordinating centre that aims at using astronomy as a tool for development in East Asia. The agreement covers two important functions. One is known as a Regional Node, which entails the coordination of astronomy-for-development activities in countries within the general geographical region of East Asia (in first instance China, Mongolia and the DPRK, but without placing firm geographical limits on the region). The other is known as a Language Expertise Centre which will deal with all aspects relating to (mainly) the Chinese language and culture. The impact of the latter may obviously spread well beyond the geographical region to other parts of the world.
Qu, Jingxuan; Gong, Daoyi; Mao, Rui; Yang, Jing; Li, Sang
In this study, the possible influence of the springtime Arctic oscillation (AO) on precipitation along the East Asian rain belt has been studied for the period of 1979 to 2014. To capture the features of the large-scale variability of the atmospheric circulation and precipitation, singular value decomposition (SVD) analysis was performed. The domain for precipitation is from 21.25 to 33.75° N and 111.25 to 133.25° E, and the 1000 hPa heights are from 20° N northward. Prior to analysis, the El Niño-Southern Oscillation (ENSO) signals were linearly fitted and subtracted from the variables of interest. The first paired modes explain 51.1 % of the total squared covariance. The spatial feature of the pressure mode is almost identical to that of the positive AO pattern, while the precipitation mode displays an overall less-than-normal anomaly along the rain belt. The AO indices are highly correlated with the time coefficients of the pressure mode at a value of 0.91, and for the time coefficients of the precipitation mode, the correlation is -0.44, both of which are significant at the 99 % level. The regional atmospheric circulation anomalies in association with the negative phase AO mode display consistent changes, including the anomalous southerly winds and vapor flux convergence in the lower troposphere over East Asia, the stronger East Asian westerly jet stream, and the enhanced ascending air motion between 20 and 30° N. There are two possible mechanisms linking the AO and East Asian circulation and precipitation, i.e., the wave-trains along the westerly jet stream from North Africa to the Middle East and East Asia and the dipole of an anti-cyclone and a cyclone over the North Pacific.
Caussy, Deoraj; Kumar, Priti; Than Sein, U.
A situation analysis was undertaken to assess impediments to health impact assessment (HIA) in the South-East Asia Region of WHO (SEARO). The countries of the region were assessed on the policy framework and procedures for HIA, existing infrastructure required to support HIA, the capacity for undertaking HIA, and the potential for intersectoral collaboration. The findings show that environmental impact assessment (EIA) is being used implicitly as a substitute for HIA, which is not explicitly or routinely conducted in virtually all countries of the Region. Therefore, policy, infrastructure, capacity, and intersectoral collaboration need strengthening for the routine implementation of HIA. PMID:12894329
Goto-Yamamoto, Nami; Sawler, Jason; Myles, Sean
Koshu is a grape cultivar native to Japan and is one of the country's most important cultivars for wine making. Koshu and other oriental grape cultivars are widely believed to belong to the European domesticated grape species Vitis vinifera. To verify the domesticated origin of Koshu and four other cultivars widely grown in China and Japan, we genotyped 48 ancestry informative single nucleotide polymorphisms (SNPs) and estimated wild and domesticated ancestry proportions. Our principal components analysis (PCA) based ancestry estimation revealed that Koshu is 70% V. vinifera, and that the remaining 30% of its ancestry is most likely derived from wild East Asian Vitis species. Partial sequencing of chloroplast DNA suggests that Koshu's maternal line is derived from the Chinese wild species V. davidii or a closely related species. Our results suggest that many traditional East Asian grape cultivars such as Koshu were generated from hybridization events with wild grape species.
Kim, S. J.; Kim, B. M.; Kim, J. H.
The Arctic is warming much more rapidly than the lower latitudes. In contrast to the rapid Arctic warming, in winters of the recent decade, the cold-air outbreaks over East Asia occur more frequently and stronger than in 1990s. By accompanying the snow over East Asia, the strong cold surges have led to a severe socio-economic impact. Such severe cold surges in recent decade over east Asia is consistent with the more dominant negative phase of the Arctic Oscillation (AO), that may be attributed by the Arctic amplification. In both observation-based reanalysis and numerical model experiments, the Arctic sea ice melting leads to the weakening of the AO polarity by reducing the meridional temperature gradient through a heat flux feedback. The Arctic warming and associated sea ice melting over the Kara-Barents area in late fall and early winter first release a lot of heat to the atmosphere from the ocean by a strong contrast in temperature and moisture and higher height anomaly is developed over the Kara/Barents and the Ural mountains The anomalous anticyclonic anomaly over the Arctic strengthen the Siberian High and at the same time the east Asian trough is developed over the western coast of the North Pacific. Through the passage between the margin of the Siberian High and east Asian tough, an extremely cold air is transported from east Siberia to east Asia for sometimes more than a week. Such a severe sold air brings about the moisture from nearby ocean, largely influencing the daily lives and economy in north East China, Korea, and Japan. The recent Arctic and associated sea ice melting is not only contributed to the local climate and weather, but also a severe weather in mid-latitudes through a modulation in polar vortex.
Yuasa, Isao; Jin, Feng; Harihara, Shinji; Matsusue, Aya; Fujihara, Junko; Takeshita, Haruo; Akane, Atsushi; Umetsu, Kazuo; Saitou, Naruya; Chattopadhyay, Prasanta K
Previous studies of four populations revealed that a hypervariable short tandem repeat (iSTR) in intron 7 of the human complement factor I (CFI) gene on chromosome 4q was unique, with 17 possible East Asian-specific group H alleles observed at relatively high frequencies. To develop a deeper anthropological and forensic understanding of iSTR, 1161 additional individuals from 11 Asian populations were investigated. Group H alleles of iSTR and c.1217A allele of a SNP in exon 11 of the CFI gene were associated with each other and were almost entirely confined to East Asian populations. Han Chinese in Changsha, southern China, showed the highest frequency for East Asian-specific group H alleles (0.201) among 15 populations. Group H alleles were observed to decrease gradually from south to north in 11 East Asian populations. This expansion of group H alleles provides evidence that southern China and Southeast Asia are a hotspot of Asian diversity and a genetic reservoir of Asians after they entered East Asia. The expected heterozygosity values of iSTR ranged from 0.927 in Thais to 0.874 in Oroqens, higher than those of an STR in the fibrinogen alpha chain (FGA) gene on chromosome 4q. Thus, iSTR is a useful marker for anthropological and forensic genetics.
Graham, David Y; Lu, Hong; Yamaoka, Yoshio
Helicobacter pylori is etiologically related to peptic ulcer disease and gastric adenocarcinomas. Reports of geographical enigmas (African, Asian, Indian and Costa Rican enigmas) are based on perceptions that clinical presentations in a population or region are not as the authors expected. We discuss the background for these enigmas and examine the evidence whether they are real or are medical myths. The African enigma was challenged almost as soon as it was proposed and recent analyses of endoscopic data have confirmed it is a myth, as H. pylori-related diseases occur in Africa at the expected frequencies. The Asian and Indian enigmas relate to gastric cancer and peptic ulcers, respectively, and when one takes the patterns of gastritis in the different regions, these enigmas disappear. The pattern of gastritis underlies and predicts the clinical outcome and the predominant pattern of gastritis has been observed to change much more rapidly than can be accounted for by changes in host genetics. There is also no evidence that these changes relate to changes in the predominant H. pylori strain. The factors that link most closely to preventing an atrophic corpus are environmental, with food preservation and diet currently assuming the most prominent roles. This focus on diseases (cancer vs duodenal ulcers) instead of the underlying patterns of gastritis has fostered, and possibly helped to perpetuate, these mythical enigmas. We suggest that a better strategy would be to focus on the pathogenesis of underlying histopathologic differences which could also lead to the identification of specific chemoprevention strategies.
Gupta, Usha; Mittal, Balraj; Kim, Jong Joo; Rai, Rajani
CD44 is a well-established cancer stem cell marker playing a crucial role in tumor metastasis, recurrence and chemo-resistance. Genetic variants of CD44 have been shown to be associated with susceptibility to various cancers; however, the results are confounding. Hence, we performed a meta-analysis to clarify these associations more accurately. Overall, rs13347 (T vs. C: OR=1.30, p=<0.004, pcorr=0.032; CT vs. CC: OR=1.29, p=0.015, pcorr=0.047; TT vs. CC: OR=1.77, p=<0.000, pcorr=0.018; CT+TT vs. CC: OR=1.34, p=<0.009, pcorr=0.041) and rs187115 (GG vs. AA: OR=2.34, p=<0.000, pcorr=0.025; AG vs. AA: OR=1.59, p=<0.000, pcorr=0.038; G vs. A allele OR=1.56, p=0.000, pcorr=0.05; AG+GG vs. AA: OR=1.63, p=<0.000, pcorr=0.013) polymorphisms were found to significantly increase the cancer risk in Asians. On the other hand, rs11821102 was found to confer low risk (A vs. G: OR=0.87, p=<0.027, pcorr=0.04; AG vs. GG: OR=0.85, p=<0.017, pcorr=0.01; AG+AA vs. GG: OR=0.86, p=<0.020, pcorr=0.02). Based on our analysis, we suggest significant role of CD44 variants (rs13347, rs187115 and rs11821102) in modulating individual's cancer susceptibility in Asians. Therefore, these variants may be used as predictive genetic biomarkers for cancer predisposition in Asian populations. However, more comprehensive studies involving other cancers and/or populations, haplotypes, gene-gene and gene-environment interactions are necessary to delineate the role of these variants in conferring cancer risk. PMID:27521214
Jia, Wei-Hua; Zhang, Ben; Matsuo, Keitaro; Shin, Aesun; Xiang, Yong-Bing; Jee, Sun Ha; Kim, Dong-Hyun; Ren, Zefang; Cai, Qiuyin; Long, Jirong; Shi, Jiajun; Wen, Wanqing; Yang, Gong; Delahanty, Ryan J.; Ji, Bu-Tian; Pan, Zhi-Zhong; Matsuda, Fumihiko; Gao, Yu-Tang; Oh, Jae Hwan; Ahn, Yoon-Ok; Park, Eun Jung; Li, Hong-Lan; Park, Ji Won; Jo, Jaeseong; Jeong, Jin-Young; Hosono, Satoyo; Casey, Graham; Peters, Ulrike; Shu, Xiao-Ou; Zeng, Yi-Xin; Zheng, Wei
To identify novel genetic factors for colorectal cancer (CRC), we conducted a genome-wide association study in East Asians. By analyzing genome-wide data in 2,098 cases and 5,749 controls, we selected 64 promising SNPs for replication in an independent set of samples including up to 5,358 cases and 5,922 controls. We identified four SNPs with a P-value of 8.58 × 10−7 to 3.77 × 10−10 in the combined analysis of all East Asian samples. Three of the four SNPs were replicated in a study conducted among 26,060 European descendants with a combined P-value of 1.22 × 10−10 for rs647161 (5q31.1), 6.64 × 10−9 for rs2423279 (20p12.3), and 3.06 × 10−8 for rs10774214 (12p13.32 near the CCND2 gene), respectively, derived from the meta-analysis of data from both East Asian and European populations. This study identified three new CRC susceptibility loci and provides additional insight into the genetics and biology of CRC. PMID:23263487
Hwang, Sung Wook; Seo, Hyungil; Kim, Gwang-Un; Song, Eun Mi; Seo, Myeongsook; Park, Sang Hyoung; Kwon, Eunja; Lee, Ho-Su; Yang, Dong-Hoon; Kim, Kyung-Jo; Ye, Byong Duk; Byeon, Jeong-Sik; Myung, Seung-Jae; Kim, Jin-Ho; Yang, Suk-Kyun
Background/Aims The reported rates of current smoking at the time of Crohn’s disease (CD) diagnosis tend to be low in East Asian studies. However, we hypothesized that East Asian patients may be reluctant to disclose their smoking history, likely because of the influence of the Confucian culture. Methods We prospectively re-evaluated the smoking status at diagnosis in 1,437 Korean CD patients whose smoking status had been reported in our previous study. Results After re-evaluation, the current smokers at diagnosis increased from 388 patients (27.0%) to 445 patients (31.0%), indicating that 12.8% (57 of 445 patients) of the current smokers at diagnosis did not disclose their smoking status at their initial evaluation. The proportion of current smokers at diagnosis who had initially concealed their smoking status was significantly higher among the female patients (29.7%, 11/37) compared with the male patients (11.3%, 46/408) (p<0.005) and among the patients who were ≤18 years old at diagnosis (56.4%, 22/39) compared with the patients >18 years old at diagnosis (8.6%, 35/406) (p<0.001). Conclusions Subgroups of Korean CD patients, particularly young patients and female patients, are reluctant to disclose their smoking history. Therefore, the suggestion that smoking is not a risk factor for the development of CD in East Asians should be made with caution. PMID:27728967
Wei, Ke; Cai, Zelin; Chen, Wen; Xu, Luyang
This study performs a comparison between models with and without well-resolved stratosphere on the simulation of the East Asian winter climate. The results reveal that the Fifth Coupled Model Inter-comparison Project (CMIP5) models with model top above the stratopause have a better simulation of the distribution of surface air temperature, sea level pressure and precipitation than the models with a low-top below the stratopause. The discrepancy of the East Asian winter climate between high-top (HT) and low-top (LT) CMIP5 models is also evident in the future projection under higher (RCP85) and midrange (RCP45) emission scenarios. The HT models present about 1.3 and 1.7 °C higher surface air temperature in East Asian region under RCP45 and RCP 85 scenarios by the end of this century than that of the LT models. Therefore, the insufficient representation of the stratosphere may lead to underestimation of the anthropogenic global warming in regional scale and hence have the potential to lead to insufficient response action and mitigation measures.
Strucken, E M; Gudex, B; Ferdosi, M H; Lee, H K; Song, K D; Gibson, J P; Kelly, M; Piper, E K; Porto-Neto, L R; Lee, S H; Gondro, C
The International Society for Animal Genetics (ISAG) proposed a panel of single nucleotide polymorphisms (SNPs) for parentage testing in cattle (a core panel of 100 SNPs and an additional list of 100 SNPs). However, markers specific to East Asian taurine cattle breeds were not included, and no information is available as to whether the ISAG panel performs adequately for these breeds. We tested ISAG's core (100 SNP) and full (200 SNP) panels on two East Asian taurine breeds: the Korean Hanwoo and the Japanese Wagyu, the latter from the Australian herd. Even though the power of exclusion was high at 0.99 for both ISAG panels, the core panel performed poorly with 3.01% false-positive assignments in the Hanwoo population and 3.57% in the Wagyu. The full ISAG panel identified all sire-offspring relations correctly in both populations with 0.02% of relations wrongly excluded in the Hanwoo population. Based on these results, we created and tested two population-specific marker panels: one for the Wagyu population, which showed no false-positive assignments with either 100 or 200 SNPs, and a second panel for the Hanwoo, which still had some false-positive assignments with 100 SNPs but no false positives using 200 SNPs. In conclusion, for parentage assignment in East Asian cattle breeds, only the full ISAG panel is adequate for parentage testing. If fewer markers should be used, it is advisable to use population-specific markers rather than the ISAG panel.
Li, Jun; Fu, Cuizhang; Lei, Guangchun
Few studies have explored the role of Cenozoic tectonic evolution in shaping patterns and processes of extant animal distributions within East Asian margins. We select Hynobius salamanders (Amphibia: Hynobiidae) as a model to examine biogeographical consequences of Cenozoic tectonic events within East Asian margins. First, we use GenBank molecular data to reconstruct phylogenetic interrelationships of Hynobius by bayesian and maximum likelihood analyses. Second, we estimate the divergence time using the bayesian relaxed clock approach and infer dispersal/vicariance histories under the 'dispersal-extinction-cladogenesis' model. Finally, we test whether evolutionary history and biogeographical processes of Hynobius should coincide with the predictions of two major hypotheses (the 'vicariance'/'out of southwestern Japan' hypothesis). The resulting phylogeny confirmed Hynobius as a monophyletic group, which could be divided into nine major clades associated with six geographical areas. Our results show that: (1) the most recent common ancestor of Hynobius was distributed in southwestern Japan and Hokkaido Island, (2) a sister taxon relationship between Hynobius retardatus and all remaining species was the results of a vicariance event between Hokkaido Island and southwestern Japan in the Middle Eocene, (3) ancestral Hynobius in southwestern Japan dispersed into the Taiwan Island, central China, 'Korean Peninsula and northeastern China' as well as northeastern Honshu during the Late Eocene-Late Miocene. Our findings suggest that Cenozoic tectonic evolution plays an important role in shaping disjunctive distributions of extant Hynobius within East Asian margins.
Mateus Pereira, L H; Socorro, A; Fernandez, I; Masleh, M; Vidal, D; Bianchi, N O; Bonatto, S L; Salzano, F M; Herrera, R J
This study attempts to ascertain genetic affinities between Native American and East Asian populations by analyzing four polymorphic Alu insertions (PAIs) and three L1 polymorphic loci. These two genetic systems demonstrated strong congruence when levels of diversity and genetic distances were considered. Overall, genetic relatedness within Native American groups does not correlate with geographical and linguistic structure, although strong grouping for Native Americans with East Asians was demonstrated, with clear discrimination from African and European groups. Most of the variation was assigned to differences occurring within groups, but the interpopulation variation found for South Amerindians was recognizably higher in comparison to the other sampled groups of populations. Our data suggest that bottleneck events followed by strong influence of genetic drift in the process of the peopling of the Americas may have been determinant factors in delineating the genetic background of present-day South Amerindians. Since no clear subgroups were detected within Native Americans and East Asians, there is no indication of multiple waves in the early colonization of the New World.
Edwards, Melissa; Cha, David; Krithika, S; Johnson, Monique; Cook, Gillian; Parra, Esteban J
In this study, we present a new quantitative method to measure iris colour based on high-resolution photographs. We applied this method to analyse iris colour variation in a sample of individuals of East Asian, European and South Asian ancestry. We show that measuring iris colour using the coordinates of the CIELAB colour space uncovers a significant amount of variation that is not captured using conventional categorical classifications, such as 'brown', 'blue' or 'green'. We tested the association of a selected panel of polymorphisms with iris colour in each population group. Six markers showed significant associations with iris colour in the European sample, three in the South Asian sample and two in the East Asian sample. We also observed that the marker HERC2 rs12913832, which is the main determinant of 'blue' versus 'brown' iris colour in European populations, is also significantly associated with central heterochromia in the European sample.
Chen, Quan; Liu, Zhifei; Kissel, Catherine
The East Asian summer monsoon controls the climatic regime of an extended region through temperature and precipitation changes. As the East Asian summer monsoon is primarily driven by the northern hemisphere summer insolation, such meteorological variables are expected to significantly change on the orbital timescale, influencing the composition of terrestrial sediments in terms of both mineralogy and geochemistry. Here we present clay mineralogy and major element composition of Core MD12-3432 retrieved from the northern South China Sea, and we investigate their relationship with the East Asian summer monsoon evolution over the last 400 ka. The variability of smectite/(illite + chlorite) ratio presents a predominant precession periodicity, synchronous with the northern hemisphere summer insolation changes and therefore with that of the East Asian summer monsoon. Variations in K2O/Al2O3 are characterized by eccentricity cycles, increasing during interglacials when the East Asian summer monsoon is enhanced. Based on the knowledge of sediment provenances, we suggest that these two proxies in the South China Sea are linked to the East Asian summer monsoon evolution with different mechanisms, which are (1) contemporaneous chemical weathering intensity in Luzon for smectite/(illite + chlorite) ratio and (2) river denudation intensity for K2O/Al2O3 ratio of bulk sediment.
Chen, Quan; Liu, Zhifei; Kissel, Catherine
The East Asian summer monsoon controls the climatic regime of an extended region through temperature and precipitation changes. As the East Asian summer monsoon is primarily driven by the northern hemisphere summer insolation, such meteorological variables are expected to significantly change on the orbital timescale, influencing the composition of terrestrial sediments in terms of both mineralogy and geochemistry. Here we present clay mineralogy and major element composition of Core MD12-3432 retrieved from the northern South China Sea, and we investigate their relationship with the East Asian summer monsoon evolution over the last 400 ka. The variability of smectite/(illite + chlorite) ratio presents a predominant precession periodicity, synchronous with the northern hemisphere summer insolation changes and therefore with that of the East Asian summer monsoon. Variations in K2O/Al2O3 are characterized by eccentricity cycles, increasing during interglacials when the East Asian summer monsoon is enhanced. Based on the knowledge of sediment provenances, we suggest that these two proxies in the South China Sea are linked to the East Asian summer monsoon evolution with different mechanisms, which are (1) contemporaneous chemical weathering intensity in Luzon for smectite/(illite + chlorite) ratio and (2) river denudation intensity for K2O/Al2O3 ratio of bulk sediment.
Chen, Quan; Liu, Zhifei; Kissel, Catherine
The East Asian summer monsoon controls the climatic regime of an extended region through temperature and precipitation changes. As the East Asian summer monsoon is primarily driven by the northern hemisphere summer insolation, such meteorological variables are expected to significantly change on the orbital timescale, influencing the composition of terrestrial sediments in terms of both mineralogy and geochemistry. Here we present clay mineralogy and major element composition of Core MD12-3432 retrieved from the northern South China Sea, and we investigate their relationship with the East Asian summer monsoon evolution over the last 400 ka. The variability of smectite/(illite + chlorite) ratio presents a predominant precession periodicity, synchronous with the northern hemisphere summer insolation changes and therefore with that of the East Asian summer monsoon. Variations in K2O/Al2O3 are characterized by eccentricity cycles, increasing during interglacials when the East Asian summer monsoon is enhanced. Based on the knowledge of sediment provenances, we suggest that these two proxies in the South China Sea are linked to the East Asian summer monsoon evolution with different mechanisms, which are (1) contemporaneous chemical weathering intensity in Luzon for smectite/(illite + chlorite) ratio and (2) river denudation intensity for K2O/Al2O3 ratio of bulk sediment. PMID:28176842
Yan, Huiping; Qian, Yun; Zhao, Chun; Wang, Hailong; Wang, Minghuai; Yang, Ben; Liu, Xiaohong; Fu, Qiang
In this study, we adopt a parametric sensitivity analysis framework that integrates the quasi-Monte Carlo parameter sampling approach and a surrogate model to examine aerosol effects on the East Asian Monsoon climate simulated in the Community Atmosphere Model (CAM5). A total number of 256 CAM5 simulations are conducted to quantify the model responses to the uncertain parameters associated with cloud microphysics parameterizations and aerosol (e.g., sulfate, black carbon (BC), and dust) emission factors and their interactions. Results show that the interaction terms among parameters are important for quantifying the sensitivity of fields of interest, especially precipitation, to the parameters. The relative importance of cloud-microphysics parameters and emission factors (strength) depends on evaluation metrics or the model fields we focused on, and the presence of uncertainty in cloud microphysics imposes an additional challenge in quantifying the impact of aerosols on cloud and climate. Due to their different optical and microphysical properties and spatial distributions, sulfate, BC, and dust aerosols have very different impacts on East Asian Monsoon through aerosol-cloud-radiation interactions. The climatic effects of aerosol do not always have a monotonic response to the change of emission factors. The spatial patterns of both sign and magnitude of aerosol-induced changes in radiative fluxes, cloud, and precipitation could be different, depending on the aerosol types, when parameters are sampled in different ranges of values. We also identify the different cloud microphysical parameters that show the most significant impact on climatic effect induced by sulfate, BC and dust, respectively, in East Asia.
Thomas, Elizabeth K.; Clemens, Steven C.; Sun, Youbin; Prell, Warren L.; Huang, Yongsong; Gao, Li; Loomis, Shannon; Chen, Guangshan; Liu, Zhengyu
For the past decade, East Asian monsoon history has been interpreted in the context of an exceptionally well-dated, high-resolution composite record of speleothem oxygen isotopes (δ18Ocave) from the Yangtze River Valley. This record is characterized by a unique spectral response, with variance concentrated predominantly within the precession band and an enigmatic lack of variance at the eccentricity and obliquity bands. Here we examine the spectral characteristics of all existing >250-kyr-long terrestrial water isotope records in Asia, including a new water isotope record using leaf wax hydrogen isotope ratios from the Chinese Loess Plateau. There exist profound differences in spectral characteristics among all orbital-scale Asian water isotope records. We demonstrate that these differences result from latitudinal gradients in the influence of the winter and summer monsoons, both of which impact climate and water isotopes throughout East Asia. Water isotope records therefore do not reflect precipitation during a single season or from a single circulation system. Rather, water isotope records in East Asia reflect the complex interplay of oceanic and continental moisture sources, operating at multiple Earth-orbital periods. These non-linear interactions are reflected in water isotope spectra by the presence of heterodynes. Although complex, we submit that water isotope records, when paired with rapidly developing isotope-enabled model simulations, will have the potential to elucidate mechanisms causing seasonal precipitation variability and moisture source variability in East Asia.
Lim, Young-Kwon; Kim, Hae-Dong
The large-scale impacts of the Arctic Oscillation (AO) and the East Atlantic/West Russia (EA/WR) teleconnection on the East Asian winter climate anomalies are compared for the past 34 winters focusing on 1) interannual monthly to seasonal temperature variability, 2) East Asian winter monsoon (EAWM), and 3) the Siberian high (SH) and cold surge. Regression analysis reveals warming by AO and EA/WR over mid-latitude East Asia during their positive phase and vice versa. The EA/WR impact is found to be comparable to the AO impact in affecting the East Asian temperature and monsoon. For example, warm (cold) months over mid-latitude East Asia during the positive (negative) AO are clearly seen when the AO and EA/WR are in the same phase. Near zero correlation is found between temperature and the AO phase when both teleconnections are in an opposite phase. The well-known negative relationship between SH and the AO phase is observed significantly more often when the AO is in the same phase with the EA/WR. Also, the indices of EAWM, cold surge, and SH are found to be more highly negative-correlated with the EA/WR rather than with the AO. The advective temperature change and associated circulation demonstrate that the anomalous large-scale field including the SH over the mid-latitude Asian inland is better represented by the EA/WR, influencing the East Asian winter climates. These results suggest that the impact of EA/WR should be considered more important than previously thought for a better understanding of East Asian winter temperature and monsoon variability.
Copeland, Wade K; Vedanthan, Rajesh; Grant, Eric; Lee, Jung Eun; Gu, Dongfeng; Gupta, Prakash C; Ramadas, Kunnambath; Inoue, Manami; Tsugane, Shoichiro; Tamakoshi, Akiko; Gao, Yu-Tang; Yuan, Jian-Min; Shu, Xiao-Ou; Ozasa, Kotaro; Tsuji, Ichiro; Kakizaki, Masako; Tanaka, Hideo; Nishino, Yoshikazu; Wang, Renwei; Yoo, Keun-Young; Ahn, Yoon-Ok; Ahsan, Habibul; Pan, Wen-Harn; Pednekar, Mangesh S; Sauvaget, Catherine; Sasazuki, Shizuka; Yang, Gong; Koh, Woon-Puay; Xiang, Yong-Bing; Ohishi, Waka; Watanabe, Takashi; Sugawara, Yumi; Matsuo, Keitaro; You, San-Lin; Park, Sue K; Kim, Dong-Hyun; Parvez, Faruque; Chuang, Shao-Yuan; Ge, Wenzhen; Rolland, Betsy; McLerran, Dale; Sinha, Rashmi; Thornquist, Mark; Kang, Daehee; Feng, Ziding; Boffetta, Paolo; Zheng, Wei
Objective To evaluate the association between body mass index and mortality from overall cardiovascular disease and specific subtypes of cardiovascular disease in east and south Asians. Design Pooled analyses of 20 prospective cohorts in Asia, including data from 835 082 east Asians and 289 815 south Asians. Cohorts were identified through a systematic search of the literature in early 2008, followed by a survey that was sent to each cohort to assess data availability. Setting General populations in east Asia (China, Taiwan, Singapore, Japan, and Korea) and south Asia (India and Bangladesh). Participants 1 124 897 men and women (mean age 53.4 years at baseline). Main outcome measures Risk of death from overall cardiovascular disease, coronary heart disease, stroke, and (in east Asians only) stroke subtypes. Results 49 184 cardiovascular deaths (40 791 in east Asians and 8393 in south Asians) were identified during a mean follow-up of 9.7 years. East Asians with a body mass index of 25 or above had a raised risk of death from overall cardiovascular disease, compared with the reference range of body mass index (values 22.5-24.9; hazard ratio 1.09 (95% confidence interval 1.03 to 1.15), 1.27 (1.20 to 1.35), 1.59 (1.43 to 1.76), 1.74 (1.47 to 2.06), and 1.97 (1.44 to 2.71) for body mass index ranges 25.0-27.4, 27.5-29.9, 30.0-32.4, 32.5-34.9, and 35.0-50.0, respectively). This association was similar for risk of death from coronary heart disease and ischaemic stroke; for haemorrhagic stroke, the risk of death was higher at body mass index values of 27.5 and above. Elevated risk of death from cardiovascular disease was also observed at lower categories of body mass index (hazard ratio 1.19 (95% confidence interval 1.02 to 1.39) and 2.16 (1.37 to 3.40) for body mass index ranges 15.0-17.4 and <15.0, respectively), compared with the reference range. In south Asians, the association between body mass index and mortality from cardiovascular disease was less
Chang, Cynthia X L; Tan, Anthony T; Or, Ming Yan; Toh, Kai Yee; Lim, Pei Yiing; Chia, Adeline S E; Froesig, Thomas M; Nadua, Karen D; Oh, Hsueh-Ling J; Leong, Hoe Nam; Hadrup, Sine R; Gehring, Adam J; Tan, Yee-Joo; Bertoletti, Antonio; Grotenbreg, Gijsbert M
Conditional ligands have enabled the high-throughput production of human leukocyte antigen (HLA) libraries that present defined peptides. Immunomonitoring platforms typically concentrate on restriction elements associated with European ancestry, and such tools are scarce for Asian HLA variants. We report 30 novel irradiation-sensitive ligands, specifically targeting South East Asian populations, which provide 93, 63, and 79% coverage for HLA-A, -B, and -C, respectively. Unique ligands for all 16 HLA types were constructed to provide the desired soluble HLA product in sufficient yield. Peptide exchange was accomplished for all variants as demonstrated by an ELISA-based MHC stability assay. HLA tetramers with redirected specificity could detect antigen-specific CD8(+) T-cell responses against human cytomegalovirus, hepatitis B (HBV), dengue virus (DENV), and Epstein-Barr virus (EBV) infections. The potential of this population-centric HLA library was demonstrated with the characterization of seven novel T-cell epitopes from severe acute respiratory syndrome coronavirus, HBV, and DENV. Posthoc analysis revealed that the majority of responses would be more readily identified by our unbiased discovery approach than through the application of state-of-the-art epitope prediction. This flow cytometry-based technology therefore holds considerable promise for monitoring clinically relevant antigen-specific T-cell responses in populations of distinct ethnicity.
Han, Siyu; Chen, Peng; Fan, Qiao; Khor, Chiea-Chuen; Sim, Xueling; Tay, Wan-Ting; Ong, Rick Twee-Hee; Suo, Chen; Goh, Liang-Kee; Lavanya, Raghavan; Zheng, Yingfeng; Wu, Renyi; Seielstad, Mark; Vithana, Eranga; Liu, Jianjun; Chia, Kee-Seng; Lee, Jeannette Jen-Mai; Tai, E-Shyong; Wong, Tien-Yin; Aung, Tin; Teo, Yik-Ying; Saw, Seang-Mei
Corneal curvature (CC) is a key determinant of major eye diseases, such as keratoconus, myopia and corneal astigmatism. No prior studies have discovered the genes for CC. Here we report the findings from four genome-wide association studies of CC in 10 008 samples from three population groups in Singapore. Our discovery phase surveyed 2867 Chinese and 3072 Malays, allowing us to identify two loci that were associated with CC variation: FRAP1 on chromosome 1p36.2 and PDGFRA on chromosome 4q12. These findings were subsequently replicated in a validation study involving an additional 2953 Asian Indians and a further collection of 1116 Chinese children. The effect sizes of the identified variants were consistent across all four cohorts, with seven single nucleotide polymorphisms (SNPs) in FRAP1 (lead SNP: rs17036350, meta P-value = 4.06 × 10(-13)) and six SNPs in PDGFRA (lead SNP: rs2114039, meta P-value = 1.33 × 10(-9)) attaining genome-wide significance in the SNP-based meta-analysis of the four studies. This is the first genome-wide survey of CC variation and we have identified two implicated loci in three genetically diverse Asian populations, suggesting the presence of common genetic etiology across multiple populations.
Choi, Ki-Seon; Cha, Yumi; Kim, Hae-Dong; Kang, Sung-Dae
In the present study, the fact that strong positive correlations have existed between East Asian summer monsoons (EASMs) and western North Pacific tropical cyclone (TC) genesis frequency over the last 37 years was found. To figure out the cause of these correlations, 7 years (positive East Asian summer monsoon index (EASMI) phase) that have the highest values and 7 years (negative EASMI phase) that have the lowest values in the normalized EASM index were selected and the differences in averages between the two phases were analyzed. In the positive EASMI phase, TCs mainly occurred in the northwestern waters of the tropical and subtropical western North Pacific and showed a tendency to move from the far eastern waters of the Philippines, pass the East China Sea, and move northward toward Korea and Japan. On the 500 hPa streamline, whereas anomalous anticyclones developed in the East Asia middle-latitude region, anomalous cyclones developed in the tropical and subtropical western North Pacific. Therefore, in this phase, whereas EASMs were weakened, western North Pacific summer monsoons (WNPSMs) were strengthened so that some more TCs could occur. In addition, in the case of the East China Sea and the southern waters of Japan located between the two anomalous pressure systems, TCs could move some more toward the East Asia middle-latitude region in this phase. According to an analysis of the 850 hPa relative vorticity, negative anomalies were strengthened in the East Asia middle-latitude region while positive anomalies were strengthened in the region south to 25 N. Therefore, in the positive EASMI phase, whereas EASMs were weakened, WNPSMs were strengthened so that some more TCs could occur. According to an analysis of the 850 and 200 hPa horizontal divergence, whereas anomalous downward flows were strengthened in the East Asia middle-latitude region, anomalous upward flows were strengthened in the tropical and subtropical western North Pacific. According to an analysis
Lindstrom, Kati; Uchiyama, Junzo
The boundaries of landscape policies often coincide with political or economic boundaries, thus creating a situation where a unit of landscape protection or management reflects more its present political status than its historico-geographical situation, its historical function and formation. At the same time, it is evident that no unit can exist independently of the context that has given birth to it and that environmental protection in isolated units cannot be very effective. The present paper will discuss inland sea as a landscape unit from prehistory to modern days and its implications for future landscape planning, using EastAsian inland sea (Japan Sea and East China Sea) rim as an example. Historically an area of active communication, EastAsian inland sea rim has become a politically very sharply divided area. The authors will bring examples to demonstrate how cultural communication on the inland sea level has influenced the formation of several landscape features that are now targets for local or national landscape protection programs, and how a unified view could benefit the future of landscape policies in the whole region.
Volkov, Sergei N; Samokhvalov, Ignatii V; Cheong, Hai Du; Kim, Dukhyeon
In this paper we present results of investigation of the main optical properties of East Asian clouds with a ground-based polarization lidar placed in Daejeon, Republic of Korea. Asian dust is located in elevated layers of the atmosphere in spring, travels long distances, and causes significant damage to ecology. We present backscattering matrices of clouds obtained from polarimetric remote measurements which comprise information on the scattering and absorption properties of cloud particles, their morphology, and spatial orientation. Theory of our applied lidar polarization experiment is presented in terms of the instrumental vectors of a transmitter and a receiver. Methods of solving linear and nonlinear systems of equations comprising echo signals are considered. Some numerical and measurement results are presented to illustrate the efficiency and versatility of the method of estimating the cloud parameters.
Arai, M.; Kimoto, M.
Using observational data and atmospheric general circulation model, relationship between surface condition over Siberia and circulation over East Asia is examined. We notice particularly the influence of springtime surface temperature over Siberia, which becomes high when the snowmelt is encouraged in situ. It is found that when the surface temperature over Siberia is high in April, blocking events over northeastern Siberia and the Okhotsk Sea in May and June occur more frequently than climatology. In the year when the surface temperature over Siberia is high, a jet stream over the north of Siberia is formed in the upper troposphere corresponding to the enhanced meridional temperature gradient, and the polar frontal jet is observed earlier than climatology. Blocking anticyclones over northeastern Siberia and the Okhotsk Sea is considered to be formed by Rossby wave propagation along the polar frontal jet in early summer. Therefore, the early establishment of the polar frontal jet is consistent with the increase of the blocking frequency. Associated with the enhancement of blocking activity is the intensification of the surface Okhotsk high, and cold anomaly to its south over the northern part of Japan during the early summer season. The amplified Okhotsk high also causes the enhancement of the Baiu front, which is a part of East Asian monsoon. The finding of this study suggests monitoring the springtime surface condition over northern Siberia as one of the promising predictors for the early summer climate over East Asia. We also examined the future climate change on the Eurasian Continent and East Asia due to the global warming, using a general circulation model. The surface temperature over Siberia increases and springtime snowmelt is enhanced under doubled CO2 condition. Summertime blocking anticyclones are also increased and the Baiu front is enhanced, compared with the simulation of the present climate. These results are manifestation of relationship between
Jung, Chun-Yong; Shin, Ho-Jeong; Jang, Chan Joo; Kim, Hyung-Jin
The summer monsoon considerably affects water resource and natural hazards including flood and drought in East Asia, one of the world's most densely populated area. In this study, we investigate future changes in summer precipitation over East Asia induced by global warming through dynamical downscaling with the Weather Research and Forecast model. We have selected a global model from the Coupled Model Intercomparison Project Phase 5 based on an objective evaluation for East Asian summer monsoon and applied its climate change under Representative Concentration Pathway 4.5 scenario to a pseudo global warming method. Unlike the previous studies that focused on a qualitative description of projected precipitation changes over East Asia, this study tried to identify the physical causes of the precipitation changes by analyzing a local moisture budget. Projected changes in precipitation over the eastern foothills area of Tibetan Plateau including Sichuan Basin and Yangtze River displayed a contrasting pattern: a decrease in its northern area and an increase in its southern area. A local moisture budget analysis indicated the precipitation increase over the southern area can be mainly attributed to an increase in horizontal wind convergence and surface evaporation. On the other hand, the precipitation decrease over the northern area can be largely explained by horizontal advection of dry air from the northern continent and by divergent wind flow. Regional changes in future precipitation in East Asia are likely to be attributed to different mechanisms which can be better resolved by regional dynamical downscaling.
Yeh, Sang-Wook; Won, Yujin; Yeo, Sae-Rim; Yim, Bo Young
The surface air temperature (SAT) in East Asia was examined in order to find global scale versus local scale factors that affected its variability during the summer (June-July-August). It was found that there exist a distinguished sub-seasonal variation, showing remarkable differences in its variability between early summer (June) and late summer (July and August). In particular, we pay attention to the variability of Korean SAT. This study revealed that Korean SAT during early and late summer is affected by different principal modes of SAT over East Asia domain. In particular, there was a significant warming trend in the Korean SAT during early summer, which was primarily influenced by a global warming trend that manifested in East Asia. Meanwhile, there exists the local scale variability of the Korean SAT, which is independent from the global warming signal. During late summer, on the other hand, the SAT variability in Korea was not significantly influenced by a warming trend, although the warming signal still accounts for majority of the SAT variance over East Asia. Instead, Korean SAT during late summer appears to be closely related to the atmospheric variability originated from the western tropical sea surface temperature (SST) forcing. These results implied that the East Asian SAT variability during early and late summer has different sources.
Kim, Beom-Jun; Ahn, Seong Hee; Kim, Hyeon-Mok; Ikegawa, Shiro; Yang, Tie-Lin; Guo, Yan; Deng, Hong-Wen; Koh, Jung-Min
Background Most reported genome-wide association studies (GWAS) seeking to identify the loci of osteoporosis-related traits have involved Caucasian populations. We aimed to identify the single nucleotide polymorphisms (SNPs) of osteoporosis-related traits among East Asian populations from the bone mineral density (BMD)-related loci of an earlier GWAS meta-analysis. Methods A total of 95 SNPs, identified at the discovery stage of the largest GWAS meta-analysis of BMD, were tested to determine associations with osteoporosis-related traits (BMD, osteoporosis, or fracture) in Korean subjects (n=1,269). The identified SNPs of osteoporosis-related traits in Korean subjects were included in the replication analysis using Chinese (n=2,327) and Japanese (n=768) cohorts. Results A total of 17 SNPs were associated with low BMD in Korean subjects. Specifically, 9, 6, 9, and 5 SNPs were associated with the presence of osteoporosis, non-vertebral fractures, vertebral fractures, and any fracture, respectively. Collectively, 35 of the 95 SNPs (36.8%) were associated with one or more osteoporosis-related trait in Korean subjects. Of the 35 SNPs, 19 SNPs (54.3%) were also associated with one or more osteoporosis-related traits in East Asian populations. Twelve SNPs were associated with low BMD in the Chinese and Japanese cohorts. Specifically, 3, 4, and 2 SNPs were associated with the presence of hip fractures, vertebral fractures, and any fracture, respectively. Conclusions Our results identified the common SNPs of osteoporosis-related traits in both Caucasian and East Asian populations. These SNPs should be further investigated to assess whether they are true genetic markers of osteoporosis. PMID:27965945
Kakuda, Tsuneo; Shojo, Hideki; Tanaka, Mayumi; Nambiar, Phrabhakaran; Minaguchi, Kiyoshi; Umetsu, Kazuo; Adachi, Noboru
Mitochondrial DNA (mtDNA) serves as a powerful tool for exploring matrilineal phylogeographic ancestry, as well as for analyzing highly degraded samples, because of its polymorphic nature and high copy numbers per cell. The recent advent of complete mitochondrial genome sequencing has led to improved techniques for phylogenetic analyses based on mtDNA, and many multiplex genotyping methods have been developed for the hierarchical analysis of phylogenetically important mutations. However, few high-resolution multiplex genotyping systems for analyzing East-Asian mtDNA can be applied to extremely degraded samples. Here, we present a multiplex system for analyzing mitochondrial single nucleotide polymorphisms (mtSNPs), which relies on a novel amplified product-length polymorphisms (APLP) method that uses inosine-flapped primers and is specifically designed for the detailed haplogrouping of extremely degraded East-Asian mtDNAs. We used fourteen 6-plex polymerase chain reactions (PCRs) and subsequent electrophoresis to examine 81 haplogroup-defining SNPs and 3 insertion/deletion sites, and we were able to securely assign the studied mtDNAs to relevant haplogroups. Our system requires only 1×10−13 g (100 fg) of crude DNA to obtain a full profile. Owing to its small amplicon size (<110 bp), this new APLP system was successfully applied to extremely degraded samples for which direct sequencing of hypervariable segments using mini-primer sets was unsuccessful, and proved to be more robust than conventional APLP analysis. Thus, our new APLP system is effective for retrieving reliable data from extremely degraded East-Asian mtDNAs. PMID:27355212
Cheung, Hoffman H. N.; Zhou, Wen
Instead of conventional East Asian winter monsoon indices (EAWMIs), we simply use two large-scale teleconnection patterns to represent long-term variations in the EAWM. First, the Urals blocking pattern index (UBI) is closely related to cold air advection from the high latitudes towards western Siberia, such that it shows an implicit linkage with the Siberian high intensity and the surface air temperature (SAT) variations north of 40°N in the EAWM region. Second, the well-known western Pacific teleconnection index (WPI) is connected with the meridional displacement of the East Asian jet stream and the East Asian trough. This is strongly related to the SAT variations in the coastal area south of 40°N in the EAWM region. The temperature variation in the EAWM region is also represented by the two dominant temperature modes, which are called the northern temperature mode (NTM) and the southern temperature mode (STM). Compared to 19 existing EAWMIs and other well-known teleconnection patterns, the UBI shows the strongest correlation with the NTM, while the WPI shows an equally strong correlation with the STM as four EAWMIs. The UBI-NTM and WPI-STM relationships are robust when the correlation analysis is repeated by (1) the 31-year running correlation and (2) the 8-year high-pass and low-pass filter. Hence, these results are useful for analyzing the large-scale teleconnections of the EAWM and for evaluating this issue in climate models. In particular, more studies should focus on the teleconnection patterns over extratropical Eurasia.
Zhou, Botao; Xu, Ying; Shi, Ying
The summer Asian-Pacific oscillation (APO), one of the major modes of climate variability over the Asian-Pacific sector, has a pronounced effect on variations of large-scale atmospheric circulations and climate. This study evaluated the capability of 30 state-of-the-art climate models among the Coupled Model Intercomparison Project Phase 5 (CMIP5) in simulating its association with the atmospheric circulations over the Asian-Pacific region and the precipitation over East Asia. Furthermore, their future connections under the RCP8.5 scenario were examined. The evaluation results show that 5 out of 30 climate models can well capture the observed APO-related features in a comprehensive way, including the strengthened South Asian high (SAH), deepened North Pacific trough (NPT) and northward East Asian jet (EAJ) in the upper troposphere; an intensification of the Asian low and the North Pacific subtropical high (NPSH) as well as a northward shift of the western Pacific subtropical high (WPSH) in the lower troposphere; and a decrease in East Asian summer rainfall (EASR) under the positive APO phase. Based on the five CMIP5 models' simulations, the dynamic linkages of the APO to the SAH, NPT, AL, and NPSH are projected to maintain during the second half of the twenty-first century. However, its connection with the EASR tends to reduce significantly. Such a reduction might result from the weakening of the linkage of the APO to the meridional displacement of the EAJ and WPSH as a response to the warming scenario.
Lee, Mo Yee; Mjelde-Mossey, LeeAnn
In traditional East Asian cultures, high value is assigned to family harmony and filial piety coupled with the expectation that elders will be honored and obeyed. A lifetime of such expectations shapes how elders perceive their role and status in the family. Problems can arise when younger, less traditional, generations do not share these expectations. This article describes a solution-focused approach that facilitates the family in creating a beneficial harmony in situations of cultural dissonance. Family members are empowered to draw on personal strengths in which multiple worldviews and values of individual members are recognized, incorporated, and negotiated.
Kaya-Bahçe, Seçil; Özmen, Erdal
This paper investigates whether the recent experience of the emerging East Asian countries with current account surpluses is consistent with the “saving glut” hypothesis and the Feldstein and Horioka puzzle. The evidence suggests that the saving retention coefficients declined substantially in most of the countries after an endogenous break date coinciding with a major exchange rate regime change with the 1997-1998 crisis. Exchange rate flexibility appears to be enhancing financial integration. The results are consistent with an “investment slump” explanation rather than the “saving glut” postulation.
Zhang, Laiming; Wang, Chengshan; Cao, Ke; Wang, Qian; Tan, Jie; Gao, Yuan
A large body of evidence suggests that there were extensive coastal mountains along the East Asian margin during the Late Cretaceous. However, current knowledge of the paleo-mountains - the period, range, and elevation - is limited. Therefore, direct paleoaltimetry is needed to validate and evaluate the paleo-mountains in East Asia. Our study area is Jiaolai Basin, which is located at the East Asian continental margin. We estimate the paleoelevation of Jiaolai Basin during the Late Cretaceous using carbonate clumped isotope paleothermometry. After correcting for seasonal preference, latitudinal difference, and secular climate change, we conclude that the paleoelevation of Jiaolai Basin was almost certainly ≥2.0 km at ∼80 Ma. Combined with the evidence from stratigraphy, paleogeography, and paleoclimatology, our results suggest that the existence of coastal mountains along East Asia during the Late Cretaceous is likely and the model of Okhotomorsk-East Asia collision is preferred.
Yao, Hong-Bing; Wang, Chuan-Chao; Tao, Xiaolan; Shang, Lei; Wen, Shao-Qing; Zhu, Bofeng; Kang, Longli; Jin, Li; Li, Hui
There is a long-going debate on the genetic origin of Chinese Muslim populations, such as Uygur, Dongxiang, and Hui. However, genetic information for those Muslim populations except Uygur is extremely limited. In this study, we investigated the genetic structure and ancestry of Chinese Muslims by analyzing 15 autosomal short tandem repeats in 652 individuals from Dongxiang, Hui, and Han Chinese populations in Gansu province. Both genetic distance and Bayesian-clustering methods showed significant genetic homogeneity between the two Muslim populations and East Asian populations, suggesting a common genetic ancestry. Our analysis found no evidence of substantial gene flow from Middle East or Europe into Dongxiang and Hui people during their Islamization. The dataset generated in present study are also valuable for forensic identification and paternity tests in China. PMID:27924949
Hopkins, James; Lee, James; Macquaid, James; Lewis, Alastair; Hamilton, Jacqueline
Observations of volatile organic compounds (VOCs), including isoprene, have been made in the atmosphere above a tropical rainforest in South-East Asia during the Oxidant and Particle Photochemical Processes above a south-east Asian tropical rainforest (OP3) experiment in July/August 2008. Seventeen flights were completed during the campaign sampling the atmosphere above significantly different terrain including primary rainforest, secondary rainforest, palm-oil plantations and the ocean with the aim of investigating the effect of changing land use on emissions of volatile organic compounds. Isoprene was found to be the dominant VOC emission from each vegetation type in terms of abundance and reactivity. Results are presented for the campaign and comparisons with ground-based observations drawn.
Huang, Wenyu; Wang, Bin; Wright, Jonathon S.
A novel dynamically based index that reflects the strength of the regional potential vorticity (PV) intrusion on the 300 K isentropic surface is proposed as a reliable measure of East Asian winter monsoon (EAWM) intensity. The index captures essential aspects of the EAWM, including its climatic influences on East Asia, its continuous weakening trend since the 1980s, and its close relationships with the Siberian high, Arctic Oscillation, and El Niño. The use of a potential vorticity framework enables the definition of a new metric called continuous PV intrusion duration (CPVID), which can be used to monitor and explain wintertime weather extremes like the extreme snowfall event that occurred in south China during January 2008. The CPVID of March is comparable to that of December, indicating that data from this month should be included in estimates of the strength of the EAWM.
Agoramoorthy, Govindasamy; Harrison, Bernard
Concern for zoo animals is palpable throughout society in many countries in South East Asia. It is important to understand problems of animal welfare in order for zoos to make significant improvement in maintaining high standards. With a case study of 3 zoos in Thailand, this article presents results for the first time on how ethics and welfare evaluations are conducted in South East Asian zoos. The study identified several major and minor welfare problems and provided constructive suggestions to zoo authorities, which in turn significantly improved the standards of animal welfare. Thus, the data presented in this article could serve as a model for other zoos to follow animal welfare evaluations locally, regionally, and globally.
Shokalsky, Sergey; Petrov, Oleg; Pospelov, Igor; Kashubin, Sergey; Sobolev, Nikolay; Petrov, Evgeny
Over the last decade under the international project of five countries, the geological surveys of Russia, China, Kazakhstan, Mongolia, and the Republic of Korea, with the participation of national academies of sciences in these countries compiled a set of digital maps at 1:2.5 M scale. It includes geological, tectonic, metallogenic maps and map of energy resources with databases for North, Central, and East Asia, area of more than 30 million km2. Map compilation was supervised by the Subcommission for Northern Eurasia and Subcommission for Tectonic Maps of the Commission for the Geological Map of the World under the auspices of UNESCO (CGMW). The set of maps was displayed at the 33rd IGC (Oslo, 2008) and 34th IGC (Brisbane, 2012). One of the largest accretion collages of orogenic belts of different ages on the planet (from the Neoproterozoic to Early Mesozoic) is clearly shown in the tectonic map compiled under the joint project. Extended polychronous mobile belt is bounded in the west by the East European Craton, in the east, by the Siberian Craton, in the south, by a chain of Gondwana cratonic blocks - North China, Tarim, Tajik. In the north it can be traced as a broad band within the Circumpolar Region, where it is limited by the North American Craton. The central part of the accretionary belt is hidden under the Meso-Cenozoic sediments of Western Siberia. Analysis of vast geological material shows that the Arctic-Asian mobile belt was formed on place of an extensive paleo-ocean, which closed with a successive rejuvenation of suture ophiolite zones from the marginal to axial zone and along strike to the north and east of the South Siberian segment towards Paleopacific. Arctic-Asian mobile belt is characterized by a complex combination of accretionary and riftogenic tectonic-magmatic processes. At its early stages, accretionary tectonics with a wide development of volcanic belts dominated; at the late ones (in the Late Paleozoic, Mesozoic, and Cenozoic
Wall, Jeffrey D; Yang, Melinda A; Jay, Flora; Kim, Sung K; Durand, Eric Y; Stevison, Laurie S; Gignoux, Christopher; Woerner, August; Hammer, Michael F; Slatkin, Montgomery
Neanderthals were a group of archaic hominins that occupied most of Europe and parts of Western Asia from ∼30,000 to 300,000 years ago (KYA). They coexisted with modern humans during part of this time. Previous genetic analyses that compared a draft sequence of the Neanderthal genome with genomes of several modern humans concluded that Neanderthals made a small (1-4%) contribution to the gene pools of all non-African populations. This observation was consistent with a single episode of admixture from Neanderthals into the ancestors of all non-Africans when the two groups coexisted in the Middle East 50-80 KYA. We examined the relationship between Neanderthals and modern humans in greater detail by applying two complementary methods to the published draft Neanderthal genome and an expanded set of high-coverage modern human genome sequences. We find that, consistent with the recent finding of Meyer et al. (2012), Neanderthals contributed more DNA to modern East Asians than to modern Europeans. Furthermore we find that the Maasai of East Africa have a small but significant fraction of Neanderthal DNA. Because our analysis is of several genomic samples from each modern human population considered, we are able to document the extent of variation in Neanderthal ancestry within and among populations. Our results combined with those previously published show that a more complex model of admixture between Neanderthals and modern humans is necessary to account for the different levels of Neanderthal ancestry among human populations. In particular, at least some Neanderthal-modern human admixture must postdate the separation of the ancestors of modern European and modern East Asian populations.
East Asian descendents during a phone screen interview. Caucasian participants identified themselves as well as the maternal and paternal ...be found in an animal study. Animal data suggest that changes in the macronutrient composition of meals from an Eastern- to a Western- style diet...may negatively impact !-cell function and insulin resistance (S. Park et al., 2005). Rats were fed either an Asian- style diet (AD; high carbohydrate
Kako, Shin'ichiro; Isobe, Atsuhiko; Kataoka, Tomoya; Hinata, Hirofumi
Large quantities of plastic litter are expected to wash ashore along the beaches of the East Asian marginal seas in the coming decade. Litter quantities were predicted using three techniques: a particle tracking model (PTM) used in conjunction with two-way PTM experiments designed to reveal litter sources, an inverse method used to compute litter outflows at each source, and a sequential monitoring system designed to monitor existing beach litter using webcams. Modeled year-to-year variation in litter quantities indicated that the amount of litter would continue to increase in the East Asian marginal seas if the level of outflow remains constant in the coming decade. The study confirms that about 3% of all East Asian beaches may potentially experience a 250-fold increase in the amount of plastic beach litter washed ashore in the next 10 years.
Homma, Yuko; Zumbo, Bruno D.; Saewyc, Elizabeth M.; Wong, Sabrina T.
We examined the psychometric properties of scores on a 6-item version of the Multigroup Ethnic Identity Measure (MEIM) among East Asian adolescents in Canada. A series of confirmatory factor analysis (CFA) was conducted for 4,190 East Asians who completed a provincial survey of students in grades 7 to 12. The MEIM measured highly correlated dimensions of ethnic identity (exploration and commitment). Further, multi-group CFA indicated that the scale measured the same constructs on the same metric across three age groups and across four groups with varying degrees of exposure to Canadian and East Asian cultures. The findings suggest the short version of the MEIM can be used to compare levels of ethnic identity across different age or acculturation groups. PMID:27833471
Hamamura, Takeshi; Park, Justin H
Research has found that contagion-minimizing behavioral tendencies are amplified in pathogen-prevalent regions. We investigated whether reactions to the "swine flu" outbreak of 2009 were stronger among East Asians than Westerners, populations residing in regions that now enjoy comparable advances in healthcare but that are characterized by relatively high and low historical pathogen prevalence, respectively. In a survey, East Asians reported greater concerns about infection, especially from foreigners. Analyses of international air travel data around the time of the outbreak provided corroborating evidence: Immediately following the outbreak, airports in the Asia-Pacific region lost more international traffic relative to their Western counterparts, and East Asian airlines reported greater declines in international traffic compared to Western airlines. These differences are unlikely to reflect objective threat posed by swine flu (whose casualties were concentrated in the Americas); rather, they appear to reflect culturally adapted behavioral patterns forged and sustained by regionally variable levels of pathogen prevalence.
Gu, Sen; Zhang, Yang; Wu, Qigang
The Arctic sea ice is suggested with wide impacts on the winter climate over East Asia. In this study, the relationship between the early autumn Arctic sea ice and the wintertime transient eddy activity over East Asia is investigated. Our singular value decomposition (SVD) analysis between the Arctic sea ice concentration (SIC) and transient eddy kinetic energy (EKE) shows that with the decrease in SIC over the Siberia coast, Kara sea and Barents sea, the EKE around the Tibetan Plateau and the downstream regions increase significantly. This leading mode indicates that more than 60% variance of the wintertime East Asian transient eddy activity can be predicted from the SIC three month earlier. Possible dynamical processes responsible for the linkage between SIC and EKE are investigated. In the upstream of Tibetan Plateau, a branch of anomalous wave train is detected propagating southward from Ural Mountains to the North China and Tibet. In the downstream region of Tibetan Plateau, with the decrease in SIC, anomalous increase in synoptic eddy generation is found with the enhanced baroclinicity over the north slope of the Tibetan Plateau, which can result in the increase in EKE as well. Those two dynamical processes both act to enhance the transient eddy activity over East Asia.
Hayakawa, Hisashi; Iwahashi, Kiyomi; Tamazawa, Harufumi; Isobe, Hiroaki; Kataoka, Ryuho; Ebihara, Yusuke; Miyahara, Hiroko; Kawamura, Akito Davis; Shibata, Kazunari
A magnetic storm around 1859 September 2, caused by a so-called Carrington flare, was the most intense in the history of modern scientific observations, and hence is considered to be a benchmark event concerning space weather. The magnetic storm caused worldwide observations of auroras, even at very low latitudes, such as Hawaii, Panama, or Santiago. Available magnetic-field measurements at Bombay, India, showed two peaks: the main was the Carrington event, which occurred in day time in East Asia; a second storm after the Carrington event occurred at night in East Asia. In this paper, we present results from surveys of aurora records in East Asia, which provide new information concerning the aurora activity of this important event. We found some new East Asian records of low-latitude aurora observations caused by a storm which occurred after the Carrington event. The size of the aurora belt of the second peak of the Carrington magnetic storm was even wider than that of usual low-latitude aurora events.
Li, Tao; Liu, Fei; Abels, Hemmo A.; You, Chen-Feng; Zhang, Zeke; Chen, Jun; Ji, Junfeng; Li, Laifeng; Li, Le; Liu, Hou-Chun; Ren, Chao; Xia, Renyuan; Zhao, Liang; Zhang, Wenfang; Li, Gaojun
Records from natural archives show that the strength of the East Asian summer monsoon (EASM) strongly depends on the orbital configuration of the Earth. However, the dominant orbital cycles driving EASM have been found to be spatially different. Speleothem stable oxygen isotopic records from southern China, which are believed to reflect large-scale changes in the Asian monsoon system, are dominated by climatic precession cycles. Further north, on the Chinese Loess Plateau (CLP), loess-and-paleosol sequences, which are argued to be controlled by monsoon intensity, are in pace with global ice volume changes dominated by obliquity, and after the mid-Pleistocene transition by 100-kyr cycles. To understand these critical discrepancies, here we apply a novel proxy based on the trace metal compositions of pedogenic carbonate in the eolian deposits on the CLP to reconstruct summer precipitation over the last 1.5 million years. Our reconstructions show that summer precipitation on the CLP is dominantly forced by obliquity not in pace with the ice-volume-imprinted loess-paleosol sequences before and after the mid-Pleistocene transition or with the precession-paced speleothem oxygen isotopic records. Coupled with climate model results, we suggest that the obliquity-driven variations of summer precipitation may originate from the gradient of boreal insolation that modulates the thermal contrast between the Asian continent and surrounding oceans.
Arshad, Shaista; Rizvi, Syed Aun R.
The EMH has been the subject of much debate over the past few decades, with a recent surge in interest in Asian markets. Asian markets which traditionally comprise of many emerging markets are more volatile and speculative in nature. The heart of our study focuses on the East Asian economies, which have experienced massive capital inflows. This begs the question of whether or not the stock markets are efficient enough for further investment and development. Our paper differs from existing literature as it focuses on deriving weak form efficiency rankings during different business cycle phases. We endeavour further to assess the volatility and business cycle phases. Taking Malaysia, Indonesia, Singapore and South Korea owing to their economic and financial development, we use MF-DFA to derive efficiency rankings and find firstly, the overall efficiency has improved over the past two decades and secondly, markets are more efficient in growth phases in comparison to its preceding decline. Similarly, employing wavelet decomposition in conjunction with EGARCH, we obtain volatility of stock markets in two distinct time horizons, i.e. short term and long term. We find the markets to be more stable during economic boom than its preceding bust. Our results confer with mainstream literature.
Wu, Zhiwei; Wang, Bin; Li, Jianping; Jin, Fei-Fei
How to predict the year-to-year variation of the east Asian summer monsoon (EASM) is one of the most challenging and important tasks in climate prediction. It has been recognized that the EASM variations are intimately but not exclusively linked to the development and decay of El Niño or La Niña. Here we present observed evidence and numerical experiment results to show that anomalous North Atlantic Oscillation (NAO) in spring (April-May) can induce a tripole sea surface temperature pattern in the North Atlantic that persists into ensuing summer and excite downstream development of subpolar teleconnections across the northern Eurasia, which raises (or lowers) the pressure over the Ural Mountain and the Okhotsk Sea. The latter strengthens (or weakens) the east Asian subtropical front (Meiyu-Baiu-Changma), leading to a strong (or weak) EASM. An empirical model is established to predict the EASM strength by combination of the El Niño-Southern Oscillation (ENSO) and spring NAO. Hindcast is performed for the 1979-2006 period, which shows a hindcast prediction skill that is comparable to the 14 state-of-the-art multimodel ensemble hindcast. Since all these predictors can be readily monitored in real time, this empirical model provides a real time forecast tool.
Wu, Z.; Wang, B.; Li, J.; Jin, F.
How to predict the year-to-year variation of the East Asian summer monsoon (EASM) is one of the most challenging and important tasks in climate prediction. It has been recognized that the EASM variations are intimately but not exclusively linked to the development and decay of El Niño or La Niña. Here, we present observed evidence and numerical experiment results to show that anomalous North Atlantic Oscillation (NAO) in spring (April-May) can induce a tripole sea surface temperature (SST) pattern in the North Atlantic that persists into ensuing summer and excite downstream development of sub-polar teleconnections across the northern Eurasia, which raises (or lowers) the pressure over the Ural Mountain and the Okhotsk Sea. The latter strengthens (or weakens) the East Asian subtropical front (Meiyu/Baiu), leading to a strong (or weak) EASM. An empirical model is established to predict the EASM strength by combination of ENSO and spring NAO. Hindcast is performed for the 1979-2006 period, which shows a hindcast prediction skill that is comparable to the 14 state-of-the-art multi-model ensemble hindcast. Since all these predictors can be readily monitored in real time, this empirical model provides a real time forecast tool.
Eroglu, Deniz; McRobie, Fiona H; Ozken, Ibrahim; Stemler, Thomas; Wyrwoll, Karl-Heinz; Breitenbach, Sebastian F M; Marwan, Norbert; Kurths, Jürgen
The East Asian-Indonesian-Australian summer monsoon (EAIASM) links the Earth's hemispheres and provides a heat source that drives global circulation. At seasonal and inter-seasonal timescales, the summer monsoon of one hemisphere is linked via outflows from the winter monsoon of the opposing hemisphere. Long-term phase relationships between the East Asian summer monsoon (EASM) and the Indonesian-Australian summer monsoon (IASM) are poorly understood, raising questions of long-term adjustments to future greenhouse-triggered climate change and whether these changes could 'lock in' possible IASM and EASM phase relationships in a region dependent on monsoonal rainfall. Here we show that a newly developed nonlinear time series analysis technique allows confident identification of strong versus weak monsoon phases at millennial to sub-centennial timescales. We find a see-saw relationship over the last 9,000 years-with strong and weak monsoons opposingly phased and triggered by solar variations. Our results provide insights into centennial- to millennial-scale relationships within the wider EAIASM regime.
Ge, Qian; Xue, Zuo; Yao, Zhigang; Zang, Zhengchen; Chu, Fengyou
The relationship between the East Asian winter monsoon (EAWM) and East Asian summer monsoon (EASM) during the Holocene is complicated and remains controversial. In this study, analysis of grain size and benthic foraminiferal oxygen isotope, as well as accelerator mass spectrometry 14C dating was performed on a sediment core retrieved from the newly revealed muddy deposit on the northern South China Sea continental shelf. The history of the EAWM and EASM were reconstructed for the last 8200 a BP. Further analysis in conjunction with previously published paleo-climate proxies revealed that the relationship between the EAWM and EASM during the Holocene is more complex than a simple and strict anti-phase one-both negative and positive correlations were identified. The EAWM and EASM are negatively correlated around 7500, 4800, 4200, 3200, and 300 a BP (cooling periods), while positively correlated around 7100, 3700, and 2100 a BP (warm periods). In particular, both the EAWM and EASM intensified during the three positive correlation periods. However, we also found that the relationship between these two sub-monsoons is anti-phase during the final phase of particularly hot periods like Holocene Optimum and Medieval warm period. The possible impact from variations of solar irradiance on the relationship between the EAWM and EASM was also discussed.
Leung, Marco Y.-T.; Cheung, Hoffman H. N.; Zhou, Wen
This paper examined the underlying dynamic mechanisms associated with the meridional displacement of the East Asian trough (EAT), which is closely related to the temperature variability in the southern part of East Asian winter monsoon (EAWM). During the southward displacement of the EAT, the Siberian high is stronger and the Aleutian low is displaced southward. This is due mainly to the anomalous cyclonic flow associated with seasonal eddies over the midlatitude central Pacific, which enhances the horizontal advection of cold (warm) air to the southern (northern) part of the EAT in the lower troposphere. The cold (warm) advection narrows (thickens) the height thickness and results in negative (positive) temperature anomalies in the southern (northern) part of the EAT. These anomalous circulation features can be reasonably explained by the phase of the El Niño-Southern Oscillation (ENSO). The results are also verified by the numerical experiments with prescribing ENSO-like heat source anomalies over the tropical eastern and western Pacific in an anomaly atmospheric general circulation model. All of these results advance our understanding for the linkage between the ENSO and the EAWM via its modulation of the EAT.
Chen, Junming; Zhao, Ping; Wang, Chengshan; Huang, Yongjian
In this study, the East Asian climate during the Late Cretaceous ( ca 80 Ma) is examined by using the Community Climate System Model Version 2 (CCSM2) from the National Center for Atmospheric Research (NCAR) and the reconstructed palaeogeographic data. The simulation results indicate that the large-scale prevailing wind directions and pressure systems over East Asia showed a remarkable seasonal variation during 80 Ma, so that it can be inferred that there existed a monsoon circulation over East Asia at that time. Compared to the present climate, the atmospheric circulation systems over the Eurasian continent in the Late Cretaceous showed a stronger meridional feature, which was possibly correspondent to a smaller lateral extension of the Eurasian continent at that time. Moreover, under a warmer background in the Late Cretaceous, the winter and summer monsoons over East Asia showed a synchronous variation, with a stronger winter monsoon as well as a stronger summer monsoon. The pattern of annual mean precipitation was similar to that of the present climate, with the maximum precipitation appearing in the intertropical convergence zone (ITCZ) between 10°S and 10°N. There was also more precipitation over the eastern coasts of the continent adjacent to the western Pacific, with the central value exceeding 1200 mm, and there was less precipitation in the midlatitudes of the inland areas. Although a more precipitation belt also appeared near 30°N over the western Pacific, which was similar to the present climate, there was no high precipitation belt over the land of East Asia. This feature implies that the uplift of the Tibetan Plateau plays an important role in the formation of the present baiu (plum rains). Moreover, the simulated climate over East Asia during 80 Ma was warmer relative to the present and the surface air temperature was 2 °C higher at the same latitudes compared to the present climate. This simulation result is closer to the estimation from the
Pollanen, Michael S
Incaprettamento is a ritualized form of ligature strangulation often associated with the Italian Mafia. The hallmarks include ligature strangulation and binding of the body in a highly stereotyped fashion. The bindings include tying the wrists and ankles together, with the body in the prone position (similar to "hogtying"), and an additional ligature encircling the neck and attached to the bindings of the extremities. The binding of the body may be performed after death is inflicted by ligature strangulation, or it may be associated with self-strangulation, as shown by the arrangement of ligatures and the position of the body. A case with great similarities to incaprettamento, in which the body was exhumed from a grave in East Timor, is described in detail. However, in addition to prone-position binding and a hyoid fracture, chopping wounds of a knee and blunt trauma to the posterior torso were found. The implication of these wounds is discussed in relation to incaprettamento.
Keinan, Alon; Mullikin, James C; Patterson, Nick; Reich, David
Large data sets on human genetic variation have been collected recently, but their usefulness for learning about history and natural selection has been limited by biases in the ways polymorphisms were chosen. We report large subsets of SNPs from the International HapMap Project that allow us to overcome these biases and to provide accurate measurement of a quantity of crucial importance for understanding genetic variation: the allele frequency spectrum. Our analysis shows that East Asian and northern European ancestors shared the same population bottleneck expanding out of Africa but that both also experienced more recent genetic drift, which was greater in East Asians.
Wilcox, L.; Highwood, E.; Dong, B.; Sutton, R.
The atmospheric component of HadGEM2-ES has been used to investigate the impacts of local and non-local emissions of anthropogenic sulphur dioxide on the East Asian summer monsoon (EASM). We focus on the very different fast responses to sudden changes in emissions from Asia and Europe. During days 1-40, Asian emissions have an impact on the sulphate burden itself over Asia, resulting in changes to the shortwave energy budget, cooling of East Asia and a weakening of the EASM. In contrast, European emissions have no significant impact on the sulphate burden over Asia, but do produce mid-tropospheric cold and dry anomaly over the European sector which is advected into Asia, where it induces atmospheric and surface feedbacks over Asia and the Western North Pacific, also weakening the EASM. The large scale pattern of changes in land-sea thermal contrast, atmospheric circulation and local precipitation over East Asia from day 40 onwards in both simulations exhibits similar structures, indicating a preferred response, and suggesting that emissions from both regions likely contributed to the observed weakening of the EASM. A weakening of the EASM tends to lead to flooding in southern China and drought in the north. Northeast Asia experienced a severe drought in summer 2014 itself within the context of two decades of dry summers. We used HadGEM3-A simulations of summer 2014 to quantify the roles of greenhouse gases, anthropogenic aerosol, and sea surface temperature in the drought. These show reductions in precipitation over East Asia in response to recent changes in sea surface temperature, which are characteristic of the warm phase of the PDO. However, model biases meant that these experiments were unable to capture the observed pattern of precipitation anomalies, thus precluding definitive attribution. These results show mechanisms by which anthropogenic aerosol could have contributed to the observed weakening of the EASM, but suggest that model biases in the Asian
This study investigated the mediating and moderating roles of self-compassion and emotional approach coping in the relationship between maladaptive perfectionism and psychological distress among East Asian international students. Data were collected through an online survey completed by 255 East Asian international students in a large public…
Park, Hye-Jin; Ahn, Joong-Bae
The combined effects of the Arctic Oscillation (AO) and Western Pacific (WP) teleconnection pattern on the East Asian winter monsoon (EAWM) over the last 56 years (1958/59-2013/2014) were investigated using NCEP/NCAR reanalysis data (Park and Ahn, 2015). The study results revealed that the effect of the AO on winter temperature in East Asia could be changed depending on the phases of the WP pattern in the North Pacific. The negative relationship between the EAWM and the AO increased when the AO and WP were in-phase with each other. Hence, when winter negative (positive) AO was accompanied by negative (positive) WP, negative (positive) temperature anomalies were dominant across the entire East Asia region. Conversely, when the AO and WP were of-of-phase, the winter temperature anomaly in East Asia did not show distinct changes. Furthermore, from the perspective of stationary planetary waves, the zonal wavenumber-2 patterns of sea level pressure and geopotential height at 500hPa circulation strengthened when the AO and WP were in-phase but were not significant for the out-of-phase condition. It explained the possible mechanism of the combined effects of the AO and WP on the circulation related to EAWM. Reference Park, H.-J., and J.-B. Ahn (2015) Combined effect of the Arctic Oscillation and the Western Pacific pattern on East Asia winter temperature, Clim. Dyn. DOI:10.1007/s00382-015-2763-2. Acknowledgements This work was funded by the Korea Meteorological Administration Research and Development Program under grant KMIPA2015-2081.
Lim, Young-Kwon; Kim, Hae-Dong
The impact of European teleconnections including the East AtlanticWest Russia (EA-WR), the Scandinavia (SCA), and the East Atlantic (EA) on East Asian winter temperature variability was quantified and compared with the combined effect of the Arctic Oscillation (AO), the Western Pacific (WP), and the El-Nino Southern Oscillation (ENSO), which are originated in the Northern Hemispheric high-latitudes or the Pacific. Three European teleconnections explained 22-25 percent of the total monthly upper-tropospheric height variance over Eurasia. Regression analysis revealed warming by EA-WR and EA and cooling by SCA over mid-latitude East Asia during their positive phase and vice versa. Temperature anomalies were largely explained by the advective temperature change process at the lower troposphere. The average spatial correlation over East Asia (90-180E, 10-80N) for the last 34 winters between observed and reconstructed temperature comprised of AO, WP and ENSO effect (AWE) was approximately 0.55, and adding the European teleconnection components (ESE) to the reconstructed temperature improved the correlation up to approximately 0.64. Lower level atmospheric structure demonstrated that approximately five of the last 34 winters were significantly better explained by ESE than AWE to determine East Asian seasonal winter temperatures. We also compared the impact between EA-WR and AO on the 1) East Asian winter monsoon, 2) cold surge, and 3) the Siberian high. These three were strongly coupled, and their spatial features and interannual variation were somewhat better explained by EA-WR than AO. Results suggest that the EA-WR impact must be treated more importantly than previously thought for a better understanding of East Asian winter temperature and monsoon variability.
Cao, Jie; Lu, Riyu; Hu, Jinming; Wang, Hai
After studying the relationship between SST in the tropical Indian Ocean (TIO), tropical western Pacific (TWP), and tropical eastern Pacific (TEP) and East Asian summer rainfall (EASR), using data provided by NOAA/OAR/ESRL PSD and the National Climate Center of China for the period 1979-2008, an index, SSTDI, was defined to describe the SST difference between the TIO and TWP. In comparison with the winter ENSO, the spring SST contrast between the TIO and TWP was found to be more significantly associated with summer rainfall in East Asia, especially along the EASR band and in Northeast China. This spring SST contrast can persist into summer, resulting in a more significant meridional teleconnection pattern of lower-tropospheric circulation anomalies over the western North Pacific and East Asia. These circulation anomalies are dynamically consistent with the summer rainfall anomaly along the EASR band. When the SSTDI is higher (lower) than normal, the EASR over the Yangtze River valley, Korea, and central and southern Japan is heavier (less) than normal. The present results suggest that this spring SST contrast can be used as a new and better predictor of EASR anomalies.
Qiao, Shaobo; Feng, Guolin
During winter, the December North Atlantic Oscillation (NAO) has an impact on the following February East Asian trough (EAT), and a significant positive correlation exists between them. It is shown that the circulation anomalies affected by the December NAO for December and for the following January are primarily confined to the Euro-Atlantic sector while they extend to East Asia during the following February, and this is related to anomalous wave trains originating from the southwestern Atlantic and spreading to the northeastern Atlantic, northern Europe, western Siberia, and East Asia. When the NAO is positive phase in December, the sea surface temperature (SST) tripole pattern is forced by persistence positive NAO from December to the following January, contributing to pronounced positive SST anomalies in midlatitude areas of the North Atlantic during the following February. The pronounced positive SST anomalies found during this period can generate feedback for atmospheric anomalies, and the westerly winds are enhanced (reduced) to the north (south) side of the positive SST anomalies, which result from strengthened (weakened) baroclinicity there. In addition, the Rossby wave source over the northeastern Atlantic shows a positive anomaly, establishing a link between the positive SST anomalies in midlatitude areas of the North Atlantic and the deepened EAT downstream.
Breyer, Christian; Bogdanov, Dmitrii; Komoto, Keiichi; Ehara, Tomoki; Song, Jinsoo; Enebish, Namjil
Further development of the North-East Asian energy system is at a crossroads due to severe limitations of the current conventional energy based system. For North-East Asia it is proposed that the excellent solar and wind resources of the Gobi desert could enable the transformation towards a 100% renewable energy system. An hourly resolved model describes an energy system for North-East Asia, subdivided into 14 regions interconnected by high voltage direct current (HVDC) transmission grids. Simulations are made for highly centralized, decentralized and country-wide grids scenarios. The results for total system levelized cost of electricity (LCOE) are 0.065 and 0.081 €/(kW·h) for the centralized and decentralized approaches for 2030 assumptions. The presented results for 100% renewable resources-based energy systems are lower in LCOE by about 30-40% than recent findings in Europe for conventional alternatives. This research clearly indicates that a 100% renewable resources-based energy system is THE real policy option.
Kim, Minjoong J.; Yeh, Sang-Wook; Park, Rokjin J.
We examine the effect of anthropogenic aerosol forcing on the East Asian summer monsoon (EASM) using the Community Atmosphere Model version 5.1.1. One control and two sensitivity model experiments were conducted in order to diagnose the separate roles played by sea surface temperature (SST) variations and anthropogenic sulfate aerosol forcing changes in East Asia. We find that the SST variation has been a major driver for the observed weakening of the EASM, whereas the effect of the anthropogenic aerosol forcing has been opposite and has slightly intensified the EASM over the recent decades. The reinforcement of the EASM results from radiative cooling by the sulfate aerosol forcing, which decelerates the jet stream around the jet's exit region. Subsequently, the secondary circulation induced by such a change in the jet stream leads to the increase in precipitation around 18-23°N. This result indicates that the increase in anthropogenic emissions over East Asia may play a role in compensating for the weakening of the EASM caused by the SST forcing.
Kurita, N.; Fujiyoshi, Y.; Nakayama, T.; Matsumi, Y.; Kitagawa, H.
To elucidate the mechanism for how the East Asian Monsoon (EAM) variability have influenced the isotope proxy records in Japan, we explore the primary driver of variations of precipitation isotopes at multiple temporal scales (event, seasonal and inter-annual scales). Using a new 1-year record of the isotopic composition of event-based precipitation and continuous near-surface water vapor at Nagoya in central Japan, we identify the key atmospheric processes controlling the storm-to-storm isotopic variations through an analysis of air mass sources and rainout history during the transport of moisture to the site, and then apply the identified processes to explain the inter-annual isotopic variability related to the EAM variability in the historical 17-year long Tokyo station record in the Global Network of Isotopes in Precipitation (GNIP). In the summer, southerly flows transport moisture with higher isotopic values from subtropical marine regions and bring warm rainfall enriched with heavy isotopes. The weak monsoon summer corresponds to enriched isotopic values in precipitation, reflecting higher contribution of warm rainfall to the total summer precipitation. In the strong monsoon summer, the sustaining Baiu rainband along the southern coast of Japan prevents moisture transport across Japan, so that the contribution of warm rainfall is reduced. In the winter, storm tracks are the dominant driver of storm-to-storm isotopic variation and relatively low isotopic values occur when a cold frontal rainband associated with extratropical cyclones passes off to the south of the Japan coast. The weak monsoon winter is characterized by lower isotopes in precipitation, due to the distribution of the cyclone tracks away from the southern coast of Japan. In contrast, the northward shift of the cyclone tracks and stronger development of cyclones during the strong monsoon winters decrease the contribution of cold frontal precipitation, resulting in higher isotopic values in
Kim, Yoonhee; Honda, Yasushi; Guo, Yue Leon; Chen, Bing-Yu; Woo, Jong-Min; Ebi, Kristie L.
Background A limited number of studies suggest that ambient temperature contributes to suicide; these studies typically focus on a single nation and use temporally and spatially aggregated data. Objective We evaluated the association between ambient temperature and suicide in multiple cities in three East Asian countries. Methods A time-stratified case-crossover method was used to explore the relationship between temperature and suicide, adjusting for potential time-varying confounders and time-invariant individual characteristics. Sex- and age-specific associations of temperature with suicide were estimated, as were interactions between temperature and these variables. A random-effects meta-analysis was used to estimate country-specific pooled associations of temperature with suicide. Results An increase in temperature corresponding to half of the city-specific standard deviation was positively associated with suicide in most cities, although average suicide rates varied substantially. Pooled country-level effect estimates were 7.8% (95% CI: 5.0, 10.8%) for a 2.3°C increase in ambient temperature in Taiwan, 6.8% (95% CI: 5.4, 8.2%) for a 4.7°C increase in Korea, and 4.5% (95% CI: 3.3, 5.7%) for a 4.2°C increase in Japan. The association between temperature and suicide was significant even after adjusting for sunshine duration; the association between sunshine and suicide was not significant. The associations were greater among men than women in 12 of the 15 cities although not significantly so. There was little evidence of a consistent pattern of associations with age. In general, associations were strongest with temperature on the same day or the previous day, with little evidence of associations with temperature over longer lags (up to 5 days). Conclusions We estimated consistent positive associations between suicide and elevated ambient temperature in three East Asian countries, regardless of country, sex, and age. Citation Kim Y, Kim H, Honda Y, Guo YL
As the workplace becomes more international, it is necessary to periodically examine the learning preferences of adults from different cultures in order to enhance their transfer of learning. This study explored whether there was any different instructional preference between Western and nonresident Far East Asian (NFEA, also Confucian-influenced)…
It is argued that it is unnecessary to propose that Confucian values explain the high achievements in math and science of the North East Asian peoples, and that these can be satisfactorily and more parsimoniously be explained by their high IQs.
Shim, Gayoung; Freund, Henning; Stopsack, Malte; Kämmerer, Annette; Barnow, Sven
The present study explores acculturation and its associated aspects of two East Asian student groups with different levels of exposure to German culture (100 international students from East Asian countries [IS]; 61 second generation students of East Asian descent [SGS]). First, we investigated the relationships between acculturation, self-construal, depressive and somatic symptoms, and differences between the student groups in these variables. Second, the four acculturation types (integration, assimilation, separation and marginalization) were examined regarding their relationship to self-construal and health outcomes. The results showed that the acculturation dimensions (mainstream, heritage) were relevant to the level of depressive symptoms for IS which was not the case for SGS. Furthermore, IS reported more somatic symptoms whereas there was no difference between the two groups in the level of depressive symptoms. In the analysis of acculturation types, assimilated and integrated students were characterized by high independent self-construal, while separated and integrated students showed high interdependent self-construal. Assimilated students displayed the least depressive symptoms of all acculturation groups. This study highlights different characteristics of East Asian students in acculturation, self-construal and health outcomes, and discusses the complexity of the relationships between acculturation types and health.
Drawing on a recent collaborative and interdisciplinary study of East Asian Images of Japan, this article discusses contemporary Chinese portrayals of Japan, their political context, and their significance for Sino-Japanese relations. It questions some widely-held assumptions concerning the extent of "thought control" in an authoritarian…
Hamamura, Toshitaka; Laird, Philip G.
This study examined relationships among acculturative stress, grade point average satisfaction, maladaptive perfectionism, and depression in 52 East Asian international students and 126 North American students. Results indicated that a combined effect of perfectionism and acculturative stress accounted for more than 30% of the variance related to…
The paper explores the adaptation experiences of East Asian masters students in the UK in dealing with western academic norms of critical thinking and debate. Through in-depth interviewing, students' perceptions of their learning experiences were explored, and stages in this adaptation process were identified, with various entry and exit routes.…
Using a narrative approach (i.e., Clandinin and Connelly 2000; Dewey 1938 ), this article explores the identity constructions and negotiations of two East Asian women teachers of English in MATESOL programs. The focus of this article explores the ways in which the two women's privileged experiences coexisted with issues of marginalization…
Gleeman, E.; Clemens, S. C.; Lawman, A. E.; Kubota, Y.; Holbourn, A. E.; Martin, A.
The East Asian Summer Monsoon (EASM) brings heavy summer rainfall to some of Asia's most densely-populated areas, impacting agricultural production and water resources. Sediment cores were recovered from International Ocean Drilling Program Site U1429 in the East China Sea (31° 37.04' N, 128° 59.50' E, 732 mbsl). This location receives runoff from the Yangtze River, which serves as a major drainage system for monsoon-induced precipitation. Hence, the δ18O record of planktonic foraminifera at Site U1429 reflects changes in regional, monsoon-driven salinity. The top 100 meters of core at Site U1429 were sampled at a preliminary resolution of 15 cm and processed to isolate the planktonic foraminifer Globigerinoides ruber for δ18O mass spectrometry analyses. Abrupt, millennial-scale regional climate variability in the EASM and its linkage to orbital forcings have been reconstructed using stratigraphic analysis of δ18O. The sub-orbital scale structure of the δ18O record over the past 400 kyr matches the structures of both the composite speleothem δ18O from eastern China (Sanbao and Hulu caves) and the planktonic δ18O record from northern South China Sea Site 1146. The similarities between these δ18O records indicate a strong regional response to monsoon forcing. Removal of the temperature component of the δ18O signal by using Mg/Ca (G. ruber) paleothermometry will provide a record of changes in the δ18O composition of seawater in response to Yangtze River runoff.
Yim, So-Young; Wang, Bin; Xing, Wen
The part II of the present study focuses on northern East Asia (NEA: 26°N-50°N, 100°-140°E), exploring the source and limit of the predictability of the peak summer (July-August) rainfall. Prediction of NEA peak summer rainfall is extremely challenging because of the exposure of the NEA to midlatitude influence. By examining four coupled climate models' multi-model ensemble (MME) hindcast during 1979-2010, we found that the domain-averaged MME temporal correlation coefficient (TCC) skill is only 0.13. It is unclear whether the dynamical models' poor skills are due to limited predictability of the peak-summer NEA rainfall. In the present study we attempted to address this issue by applying predictable mode analysis method using 35-year observations (1979-2013). Four empirical orthogonal modes of variability and associated major potential sources of variability are identified: (a) an equatorial western Pacific (EWP)-NEA teleconnection driven by EWP sea surface temperature (SST) anomalies, (b) a western Pacific subtropical high and Indo-Pacific dipole SST feedback mode, (c) a central Pacific-El Nino-Southern Oscillation mode, and (d) a Eurasian wave train pattern. Physically meaningful predictors for each principal component (PC) were selected based on analysis of the lead-lag correlations with the persistent and tendency fields of SST and sea-level pressure from March to June. A suite of physical-empirical (P-E) models is established to predict the four leading PCs. The peak summer rainfall anomaly pattern is then objectively predicted by using the predicted PCs and the corresponding observed spatial patterns. A 35-year cross-validated hindcast over the NEA yields a domain-averaged TCC skill of 0.36, which is significantly higher than the MME dynamical hindcast (0.13). The estimated maximum potential attainable TCC skill averaged over the entire domain is around 0.61, suggesting that the current dynamical prediction models may have large rooms to improve
Guo, Zhun; Zhou, Tianjun; Wang, Minghuai; ...
The impacts of cloud radiative heating on East Asian Summer Monsoon (EASM) over the southeastern China (105°-125°E, 20°-35°N) are explained by using the Community Atmosphere Model version 5 (CAM5). Sensitivity experiments demonstrate that the radiative heating of clouds leads to a positive effect on the local EASM circulation over southeastern China. Without the radiative heating of cloud, the EASM circulation and precipitation would be much weaker than that in the normal condition. The longwave heating of clouds dominates the changes of EASM circulation. The positive effect of clouds on EASM circulation is explained by the thermodynamic energy equation, i.e. themore » different heating rate between cloud base and cloud top enhances the convective instability over southeastern China, which enhances updraft consequently. The strong updraft would further result in a southward meridional wind above the center of the updraft through Sverdrup vorticity balance.« less
Dempsey, Jessica T.; Ho, Paul T. P.; Walther, Craig; Friberg, Per; Bell, Graham S.; Parsons, Harriet; Chen, Ming-Tang
The newly formed East Asian Observatory assumed operations of the James Clerk Maxwell Telescope in March of 2015. In just three weeks, the facility needed to run up completely mothballed observatory operations, introduce the telescope to a vast new scientist base with no familiarity with the facility, and create a non-existent science program. The handover to the EAO has since been a succession of challenging time-lines, and nearly unique problems requiring novel solutions. The results, however, have been spectacular, with subscription rates at unprecedented levels, a new series of Large Programs underway, as well as an exciting Future Instrumentation Project that together promises to keep JCMT at the forefront of wide-field submillimeter astronomy for the next decade.
Shergis, Johannah Linda; Wu, Lei; May, Brian H; Zhang, Anthony Lin; Guo, Xinfeng; Lu, Chuanjian; Xue, Charlie Changli
Chronic cough is a significant health burden. Patients experience variable benefits from over the counter and prescribed products, but there is an unmet need to provide more effective treatments. Natural products have been used to treat cough and some plant compounds such as pseudoephedrine from ephedra and codeine from opium poppy have been developed into drugs. Text mining historical literature may offer new insight for future therapeutic development. We identified natural products used in the East Asian historical literature to treat chronic cough. Evaluation of the historical literature revealed 331 natural products used to treat chronic cough. Products included plants, minerals and animal substances. These natural products were found in 75 different books published between AD 363 and 1911. Of the 331 products, the 10 most frequently and continually used products were examined, taking into consideration findings from contemporary experimental studies. The natural products identified are promising and offer new directions in therapeutic development for treating chronic cough.
Chong, Kar Hau; Wu, Suet Kei; Noor Hafizah, Yatiman; Bragt, Marjolijn C E; Poh, Bee Koon
This article aims to describe the eating habits of Malaysian children using a nationally representative data set from the South East Asian Nutrition Surveys (SEANUTS) in Malaysia. A total of 2797 children aged 2 to 12 years were included in this analysis. Eating habits and dietary intakes of children were assessed using questionnaires. Overall, 56.1% of children consumed 3 main meals every day. Approximately 20% of children snacked 3 times per day, whereas 9.7% ate fast food on a weekly basis. Irregular meal patterns were significantly associated with lower micronutrient intakes, and the groups with higher odds for this pattern were older children, Malays, and those living in rural areas. Considering the relatively high rate of irregular meal consumption and its potential influence on dietary nutrient intake, persistent efforts must be continued to promote and inculcate healthy eating habits among children from an early age.
Barry, Declan T; Beitel, Mark
Although sex role ideology (i.e., beliefs about the proper roles for men and women) is linked with self-definition and male-female interactions, researchers have rarely examined such beliefs among U.S. immigrants. This study examined the cultural (ethnic identity, self-construal) and demographic (gender, age, years in United States) correlates of sex role ideology among 170 (88 male, 82 female) East Asian immigrants using psychometrically established measures. Male participants who endorsed ethnic identity and interdependent self-construal were more likely to report traditional sex roles; female participants who lived for a longer period of time in the United States and who endorsed independent self-construal were more likely to report sex role equality. Clinicians should consider assessing sex role ideology to reduce the likelihood of stereotyping their immigrant clients.
Barry, Declan T; Bernard, Matthew J; Beitel, Mark
This study examined the relationship between gender, sex role ideology, and self-esteem among 170 (88 male, 82 female) East Asian immigrants in the United States. Participants were administered a battery of psychometrically established measures. Men and women did not differ on personal or collective self-esteem (CSE). Women who endorsed traditional sex roles were significantly more likely to report higher private, identity, and total CSE. Personal self-esteem was a significant independent predictor of traditional sex role for women. Participants who endorsed sex role equality were significantly more likely to report public, membership, and total CSE. Sex role equality was associated with enhanced private CSE for men and attenuated personal self-esteem for women. These findings point to the importance of assessing multiple facets of self-esteem, which appear to be differentially associated with sex role ideology for men and women.
Haupt, Joachim; Müller, Frank
Secretion products from the opisthosomal defense gland of south east Asian whip scorpions were identified for the first time by gas-chromatography and mass-spectrometry. Specimens of the genera Hypoctonus, Typopeltis and Ginosigma were tested. While some ingredients are present in large concentrations, others are possibly only side products and may be synthesized more incidentally. For this reason no important functional role is attributed to them. There are considerable individual differences concerning the concentrations of various ingredients. While the secretion products of most species of the genus Typopeltis--similar to Mastigoproctus--are characterized by acetic and octanoic acid in large concentrations, the secretion product of Hypoctonus siamensis provides octanoic acid only in a very low concentration but it is characterized by hexyl acetate.
Guo, Zhun; Zhou, Tianjun; Wang, Minghuai; Qian, Yun
The impacts of cloud radiative heating on East Asian Summer Monsoon (EASM) over the southeastern China (105°-125°E, 20°-35°N) are explained by using the Community Atmosphere Model version 5 (CAM5). Sensitivity experiments demonstrate that the radiative heating of clouds leads to a positive effect on the local EASM circulation over southeastern China. Without the radiative heating of cloud, the EASM circulation and precipitation would be much weaker than that in the normal condition. The longwave heating of clouds dominates the changes of EASM circulation. The positive effect of clouds on EASM circulation is explained by the thermodynamic energy equation, i.e. the different heating rate between cloud base and cloud top enhances the convective instability over southeastern China, which enhances updraft consequently. The strong updraft would further result in a southward meridional wind above the center of the updraft through Sverdrup vorticity balance.
Du, S.; Li, B.; Chen, M.; Zhang, D.; Xiang, R.; Niu, D.
The Bohai Sea coastal zone of China faces the Pacific Ocean to the east and the Eurasian continent to the west, hence, this region is influenced by both the ocean and continental landmasses. The Bohai Sea coastal zone has significant monsoon climate characteristics and a strong sensitivity to climate change. The Miaodao stratigraphical section (MDS) contains historical information about climate features in the region, especially the high-frequency variations during the last interglacial, sea level changes, and the evolution of the East Asian monsoon. By analyzing the ages of different sedimentary facies in combination with proxy paleoclimatic indices (i.e., grain <63 μm fraction, average grain size (Mz), clay + silt/sand content (SC/D), magnetic susceptibility, and the ratios of Na2O/Al2O3 and (Al2O3+TOFe)/SiO2, in the fifth segments of the MDS from the last-interglacial (MDS5), we conclude that subsections 5a, 5c, and 5e were controlled by summer monsoons, whereas subsections 5b and 5d were formed when winter monsoons prevailed. These results were similar to oxygen isotope analyses from previous studies including the Spectral Mapping Project (SPECMAP) and the North Greenland Ice Core Project (NorthGRIP). Five and a half comparable oscillations in proxy indices that were dated to ca. 116.1, 118.3, 121.2, 122.7, 125.9, and 128.7 ka occurred within the MDS 5e subsection when winter monsoon winds strengthened. This millennial-scale climate variability during the Eemian period may have reached up to ten and a half oscillations with a quasi-periodicity of approximately a 1,470 year cycle during the late glacial period. This rapid period of climate change has been recorded in northern and central Europe, central Asia, as well as in East Asia. The climate forming mechanism was probably initiated by changes in solar activity, and driven by the East Asian monsoon and sea level oscillations. Comparison of Miaodao section records with other paleoclimatic records during the
Abdillah, M. R.; Kanno, Y.; Iwasaki, T.
This study investigates possible interactions between East Asian cold air outbreak (CAOs) and tropical variability during boreal winter (DJF), particularly in interannual and intraseasonal time scale. The definition of CAOs follows the recent definition that used isentropic coordinate. The CAO definition is based on anomalously large equatorward mass flux below θ=280 K crossing 45°N latitude. This location represents the maxima of extratropical direct (ETD) circulation in the viewpoint of mass-weighted isentropic meridional circulation (MIM; Iwasaki and Mochizuki 2012; Iwasaki et al. 2014; Shoji et al. 2014). Unlike most CAO studies, we utilize quantitative definition of cold air mass (CAM) to estimate the CAO. EOF analysis on the seasonal-mean equatorward CAM flux in East Asia reveals two CAO types that can be easily distinguished as the western type CAO (90°-135°E) and eastern type CAO (135°-180°E). These CAOs are significantly associated with remote forcing in tropics. The western CAO tends to be in phase with La Nina event. Otherwise, eastern CAO is dominant in El Nino event. In sub-seasonal scale, day-lagged analysis of CAO event enables us to identify the impact and precursor during CAO event. The impact of western CAO is robust on the development of precipitation downstream around South China Sea and Philippines. Otherwise, eastern CAO event shows less impact possibly due to rapid disappearance over ocean. Remarkably, the preconditioning time of East Asian CAO is accompanied by large-scale organized convection in tropics. It is revealed that western CAOs favor to occur when the MJO arrives in Maritime Continent (MJO phase 4-5). On the other hand, eastern CAOs tend to occur when the MJO arrives in central Pacific (MJO phase 7-8). We investigated that these remote interactions are possibly driven by upper-tropospheric Rossby wave train forcing and enhanced local Hadley circulation associated with MJO-like tropical precipitation. These indicate potential
Chong, J.; Yuan, H.; French, S. W.; Romanowicz, B. A.; Ni, S.
East Asia is a seismically active region featuring active tectonic belts, such as the Himalaya collision zone, western Pacific subduction zones and the Tianshan- Baikal tectonic belt. In this study, we applied full waveform time domain tomography to image 3D isotropic, radially and azimuthally anisotropic upper mantle shear velocity structure of East Asia. High quality teleseismic waveforms were collected for both permanent and temporary stations in the target and its adjacent regions, providing good ray path coverage of the study region. Fundamental and overtone wave packets, filtered down to 60 sec, were inverted for isotropic and radially anisotropic shear wave structure using normal mode asymptotic coupling theory (NACT: Li and Romanowicz, 1995). Joint inversion of SKS measurements and seismic waveforms was then carried out following the methodology described in (Marone and Romanowicz, 2007). The 3D velocity model shows strong lateral heterogeneities in the target region, which correlate well with the surface geology in East Asia. Our model shows that Indian lithosphere has subducted beneath Tibet with a different northern reach from western to eastern Tibet,. We also find variations of the slab geometry in Western Pacific subduction zones. Old and stable regions, such as, Indian shield, Siberia platform, Tarim and Yangtze blocks are found to have higher shear wave velocity in the upper mantle. Lower velocity anomalies are found in regions like Baikal rift, Tienshan, Indochina block, and the regions along Japan island-Ryukyu Trench and Izu-bonin Trench. The dominant fast and slow velocity boundaries in the study region are well correlated with tectonic belts, such as the central Asian orogenic belt and Alty/Qilian-Qinling/Dabie orogenic belt. Our radially anisotropic model shows Vsh> Vsv in oceanic regions and at larger depths(>300km), and Vsv > Vsh in some orogenic zones.. We'll show preliminary results of azimuthally anisotropic joint inversion of SKS
Zhao, Chun; Wang, Yuhang; Yang, Qing; Fu, Rong; Cunnold, Derek; Choi, Yunsoo
Tropospheric O3 columns retrieved from OMI and MLS measurements, CO columns from MOPITT, and tropospheric O3 and CO concentrations from TES from May to August in 2006 are analyzed using the Regional chEmical and trAnsport Model (REAM) to investigate the impact of the East Asian summer monsoon on the air quality over China. The observed and simulated migrations of O3 and CO are in good agreement, demonstrating that the summer monsoon significantly affects the air quality over southeastern China and this influence extends to central East China from June to July. Enhancements of CO and O3 over southeastern China disappear after the onset of the summer monsoon and re-emerge in August after the monsoon wanes. The pre-monsoon high O3 concentrations over southern China are due to photochemical production from pollutant emissions and the O3 transport from the stratosphere. In the summer monsoon season, the O3 concentrations are relatively low over monsoon-affected regions because of the transport of marine air masses and weak photochemical activity. We find that the monsoon system strongly modulates the pollution problem over a large portion of East China in summer, depending on its strength and tempo-spatial extension. Model results also suggest that transport from the stratosphere and long-range transport from East China and South/Central Asia all make significant contributions to O3 enhancements over West China. Satellite observations provide valuable information for investigating the monsoon impact on air quality, particularly for the regions with limited in situ measurements.
Zou, Liwei; Zhou, Tianjun
In this study, a developed regional ocean-atmosphere coupled model FROALS was applied to the CORDEX East Asia domain. The performance of FROALS in the simulation of Asian summer monsoon during 1989-2010 was assessed using the metrics developed by the CLIVAR Asian-Australian Monsoon Panel Diagnostics Task Team. The results indicated that FROALS exhibited good performance in simulating Asian summer monsoon climatology. The simulated JJA mean SST biases were weaker than those of the CMIP5 multi-model ensemble mean (MMEM). The skill of FROALS approached that of CMIP5 MMEM in terms of the annual cycle of Asian summer monsoon. The simulated monsoon duration matched the observed counterpart well (with a spatial pattern correlation coefficient of 0.59). Some biases of CMIP5 MMEM were also found in FROALS, highlighting the importance of local forcing and model physics within the Asian monsoon domain. Corresponding to a strong East Asian summer monsoon, an anomalous anticyclone was found over western North Pacific in both observation and simulation. However, the simulated strength was weaker than the observed due to the responses to incorrect sea surface anomalies over the key regions. The model also accurately captured the spatial pattern of the intraseasonal variability variance and the extreme climate indices of Asian summer monsoons, although with larger amplitude. The results suggest that FROALS could be used as a dynamical downscaling tool nested within the global climate model with coarse resolution to develop high-resolution regional climate change projections over the CORDEX East Asia domain.
Kamiya, Takeshi; Joh, Takashi; Sollano, Jose D.; Zhu, Qi; Kachintorn, Udom; Aziz Rani, Abdul; Hahm, Ki-Baik; Takahashi, Shin'ichi; Kinoshita, Yoshikazu; Matsumoto, Takayuki; Naito, Yuji; Takeuchi, Koji; Arakawa, Tetsuo; Terano, Akira
Background and Aim. New diagnostic or therapeutic methods in endoscopy have been used. Current clinical application of these procedures is not well known. The aim of this study is to investigate the present situation on endoscopic diagnosis and treatment of gastrointestinal disorders in East Asian countries. Method. A representative member from the International Gastrointestinal Consensus Symposium Committee provided a questionnaire to physicians in China, Indonesia, Japan, Korea, the Philippines, and Thailand. Results. In total, 514 physicians including gastroenterologists, surgeons, and general practitioners enrolled. The most frequently occurring disorder as the origin of upper gastrointestinal bleeding is gastric ulcer. Capsule endoscopy is selected as the first choice for the diagnosis of small intestine bleeding. The second choice was double-balloon endoscopy or angiography. For patients with gastric adenoma, the number of physicians who choose endoscopic mucosal resection is larger than those selecting endoscopic submucosal dissection (ESD) in China, Indonesia, the Philippines, and Thailand. ESD is chosen first in Japan and Korea. Conclusion. New instruments or techniques on endoscopy have not come into wide use yet, and there is diversity in the situation on it in Asian countries. We should unify the endoscopic diagnostic criteria or treated strategy in patients with GI disease. PMID:23093833
Gocha, Timothy P; Vercellotti, Giuseppe; McCormick, Lara E; Van Deest, Traci L
Estimating stature in human skeletal remains of Asian ancestry is problematic for forensic anthropologists due to the paucity and uncertain suitability of regression formulae. To address this issue, our study analyzed 64 individuals from a modern skeletal collection of South-East Asian origin and developed population-specific ordinary least squares regression formulae to estimate skeletal height from each of the long bones of the upper and lower limbs, as well as from trunk length. Results indicate that the most accurate estimates of skeletal height from a single bone (as measured by standard error of the estimate-SEE) are from tibial length in males (SEE = 2.40 cm) and from humeral length in females (SEE = 2.59 cm), followed by femoral length (SEE = 2.84 cm). When multiple elements are considered, the combination of femoral and tibial length yields the best estimates in both sexes as well as combined sex samples (male SEE = 2.40 cm; female SEE = 2.77 cm; combined sex SEE = 2.54 cm).
Al-Ghaferi, Nadia; Kolodziejek, Jolanta; Nowotny, Norbert; Coquet, Laurent; Jouenne, Thierry; Leprince, Jérôme; Vaudry, Hubert; King, Jay D; Conlon, J Michael
Peptidomic analysis of norepinephrine-stimulated skin secretions of the South-East Asian frog Hylarana erythraea (formerly Rana erythraea partim) has led to the identification of multiple peptides with antimicrobial activity. Structural characterization of the peptides demonstrated that they belong to the brevinin-1 (3), brevinin-2 (2), esculentin-2 (4), and temporin (1) families. The values in parentheses indicate the number of paralogs. In addition, a peptide (GVIKSVLKGVAKTVALG ML.NH(2)) was isolated that shows some structural similarity to the brevinin-2-related peptides (B2RP) previously isolated from North American frogs of the genus Lithobates. A synthetic replicate of the species B2RP showed broad-spectrum growth inhibitory activity against reference strains of Escherichia coli (MIC=12.5 microM), Staphylococcus aureus (MIC=12.5 microM) and Candida albicans (MIC=50 microM) and was active against multidrug-resistant clinical isolates of Acetinobacter baumannii (MIC in the range 6-12.5 microM). The hemolytic activity of the peptide was relatively low (LC(50)=280 microM). Phylogenetic analysis based upon the amino acid sequences of 47 brevinin-2 peptides from 17 Asian species belonging to the family Ranidae provides support for the placement of H. erythraea in the genus Hylarana.
Yancheva, Gergana; Nowaczyk, Norbert R; Mingram, Jens; Dulski, Peter; Schettler, Georg; Negendank, Jörg F W; Liu, Jiaqi; Sigman, Daniel M; Peterson, Larry C; Haug, Gerald H
The Asian-Australian monsoon is an important component of the Earth's climate system that influences the societal and economic activity of roughly half the world's population. The past strength of the rain-bearing East Asian summer monsoon can be reconstructed with archives such as cave deposits, but the winter monsoon has no such signature in the hydrological cycle and has thus proved difficult to reconstruct. Here we present high-resolution records of the magnetic properties and the titanium content of the sediments of Lake Huguang Maar in coastal southeast China over the past 16,000 years, which we use as proxies for the strength of the winter monsoon winds. We find evidence for stronger winter monsoon winds before the Bølling-Allerød warming, during the Younger Dryas episode and during the middle and late Holocene, when cave stalagmites suggest weaker summer monsoons. We conclude that this anticorrelation is best explained by migrations in the intertropical convergence zone. Similar migrations of the intertropical convergence zone have been observed in Central America for the period ad 700 to 900 (refs 4-6), suggesting global climatic changes at that time. From the coincidence in timing, we suggest that these migrations in the tropical rain belt could have contributed to the declines of both the Tang dynasty in China and the Classic Maya in Central America.
Choi, M.; Kim, H.; Cho, E.
It is now well understood that water, carbon, and energy fluxes at the surface/atmosphere interface are highly dependent on soil moisture (SM). In addition, SM is required to be used as realistic initial states for the SM variables, for climate predictions and weather forecasting. As satellite remote-sensing have developed greatly, global surface SM datasets have been produced based on several satellites. Three satellites-based SM datasets were inter-compared under different land-cover over East Asia to select most reliable satellite for retrieving SM datasets in dust source regions. We estimated satellite sensors with 1) Soil Moisture and Ocean Salinity (SMOS), 2) Advanced Scatterometer (ASCAT), and 3) Advanced Microwave Scanning Radiometer 2 (AMSR2) and Global Land Data Assimilation System (GLDAS) was used as reference datasets. In case of arid areas (desert and semi-desert), SMOS-retrieved SM products showed best accuracy (radiometers have generally exhibited a better performance than scatterometers in dry areas). For this reason, SMOS SM products were utilized to retrieve SM over desert areas. The regions that are susceptible to dust outbreaks were investigated using the dust outbreak probability functions (DOPF). Based on DOPF, about 58% of the total number of dust events occurred in regions with a high level of vulnerability where dust outbreaks were predicted with a probability higher than 60%. The SMOS-based DOPF was calculated to be about 62.4% of the dust outbreak vulnerability (DOV) level of the desert areas. Interestingly, East Asian deserts showed an increasing tendency for a high level of DOV during the study period. Those areas were judged to be sources from which dust could be transported to neighboring countries (e.g., Korea and Japan) which can lead to Asian dust storms. These results may allow us to predict trends of dust outbreaks in order to prepare the corresponding disaster response systems.
Lee, Seungjoon; Ryu, Youngryel; Jiang, Chongya
Roof surface materials, such as green and white roofs, have attracted attention in their role in urban heat mitigation, and various studies have assessed the cooling performance of roof surface materials during hot and sunny summer seasons. However, summers in the East Asian monsoon climate region are characterized by significant fluctuations in weather events, such as dry periods, heatwaves, and rainy and cloudy days. This study investigated the efficacy of different roof surface materials for heat mitigation, considering the temperatures both at and beneath the surface of the roof covering materials during a summer monsoon in Seoul, Korea. We performed continuous observations of temperature at and beneath the surface of the roof covering materials, and manual observation of albedo and the normalized difference vegetation index for a white roof, two green roofs (grass (Poa pratensis) and sedum (Sedum sarmentosum)), and a reference surface. Overall, the surface temperature of the white roof was significantly lower than that of the grass and sedum roofs (1.1 °C and 1.3 °C), whereas the temperature beneath the surface of the white roof did not differ significantly from that of the grass and sedum roofs during the summer. The degree of cloudiness significantly modified the surface temperature of the white roof compared with that of the grass and sedum roofs, which depended on plant metabolisms. It was difficult for the grass to maintain its cooling ability without adequate watering management. After considering the cooling performance and maintenance efforts for different environmental conditions, we concluded that white roof performed better in urban heat mitigation than grass and sedum during the East Asian summer monsoon. Our findings will be useful in urban heat mitigation in the region.
Wu, Jonny; Suppe, John; Lu, Renqi; Kanda, Ravi
We reconstructed Philippine Sea and East Asian plate tectonics since 52 Ma from 28 slabs mapped in 3-D from global tomography, with a subducted area of ~25% of present-day global oceanic lithosphere. Slab constraints include subducted parts of existing Pacific, Indian, and Philippine Sea oceans, plus wholly subducted proto-South China Sea and newly discovered "East Asian Sea." Mapped slabs were unfolded and restored to the Earth surface using three methodologies and input to globally consistent plate reconstructions. Important constraints include the following: (1) the Ryukyu slab is ~1000 km N-S, too short to account for ~20° Philippine Sea northward motion from paleolatitudes; (2) the Marianas-Pacific subduction zone was at its present location (±200 km) since 48 ± 10 Ma based on a >1000 km deep slab wall; (3) the 8000 × 2500 km East Asian Sea existed between the Pacific and Indian Oceans at 52 Ma based on lower mantle flat slabs; (4) the Caroline back-arc basin moved with the Pacific, based on the overlapping, coeval Caroline hot spot track. These new constraints allow two classes of Philippine Sea plate models, which we compared to paleomagnetic and geologic data. Our preferred model involves Philippine Sea nucleation above the Manus plume (0°/150°E) near the Pacific-East Asian Sea plate boundary. Large Philippine Sea westward motion and post-40 Ma maximum 80° clockwise rotation accompanied late Eocene-Oligocene collision with the Caroline/Pacific plate. The Philippine Sea moved northward post-25 Ma over the northern East Asian Sea, forming a northern Philippine Sea arc that collided with the SW Japan-Ryukyu margin in the Miocene (~20-14 Ma).
Goh, Chee Leok; Abad-Casintahan, Flordeliz; Aw, Derrick Chen Wee; Baba, Roshidah; Chan, Lee Chin; Hung, Nguyen Thanh; Kulthanan, Kanokvalai; Leong, Hoe Nam; Medina-Oblepias, Marie Socouer; Noppakun, Nopadon; Sitohang, Irma Bernadette; Sugito, Titi Lestari; Wong, Su-Ni
The management of acne in South-East Asia is unique, as Asian skin and local variables require a clinical approach unlike that utilized in other parts of the world. There are different treatment guidelines per country in the region, and a group of leading dermatologists from these countries convened to review these guidelines, discuss current practices and recent advances, and formulate consensus guidelines to harmonize the management of acne vulgaris in the region. Emphasis has been placed on formulating recommendations to impede the development of antibiotic resistance in Propionibacterium acnes. The group adopted the Acne Consensus Conference system for grading acne severity. The group recommends that patients may be treated with topical medications including retinoids, benzoyl peroxide (BPO), salicylic acid, a combination of retinoid and BPO, or a combination of retinoids and BPO with or without antibiotics for mild acne; topical retinoid with topical BPO and a oral antibiotic for moderate acne; and oral isotretinoin if the patient fails first-line treatment (a 6- or 8-week trial of combined oral antibiotics and topical retinoids with BPO) for severe acne. Maintenance acne treatment using topical retinoids with or without BPO is recommended. To prevent the development of antibiotic resistance, topical antibiotics should not be used as monotherapy or used simultaneously with oral antibiotics. Skin care, comprised of cleansing, moisturizing and sun protection, is likewise recommended. Patient education and good communication is recommended to improve adherence, and advice should be given about the characteristics of the skin care products patients should use.
East and Southeast Asia is a complex assembly of allochthonous continental terranes, island arcs, accretionary complexes and small ocean basins. The boundaries between continental terranes are marked by major fault zones or by sutures recognized by the presence of ophiolites, mélanges and accretionary complexes. Stratigraphical, sedimentological, paleobiogeographical and paleomagnetic data suggest that all of the East and Southeast Asian continental terranes were derived directly or indirectly from the Iran-Himalaya-Australia margin of Gondwanaland. The evolution of the terranes is one of rifting from Gondwanaland, northwards drift and amalgamation/accretion to form present day East Asia. Three continental silvers were rifted from the northeast margin of Gondwanaland in the Silurian-Early Devonian (North China, South China, Indochina/East Malaya, Qamdo-Simao and Tarim terranes), Early-Middle Permian (Sibumasu, Lhasa and Qiangtang terranes) and Late Jurassic (West Burma terrane, Woyla terranes). The northwards drift of these terranes was effected by the opening and closing of three successive Tethys oceans, the Paleo-Tethys, Meso-Tethys and Ceno-Tethys. Terrane assembly took place between the Late Paleozoic and Cenozoic, but the precise timings of amalgamation and accretion are still contentious. Amalgamation of South China and Indochina/East Malaya occurred during the Early Carboniferous along the Song Ma Suture to form "Cathaysialand". Cathaysialand, together with North China, formed a large continental region within the Paleotethys during the Late Carboniferous and Permian. Paleomagnetic data indicate that this continental region was in equatorial to low northern paleolatitudes which is consistent with the tropical Cathaysian flora developed on these terranes. The Tarim terrane (together with the Kunlun, Qaidam and Ala Shan terranes) accreted to Kazakhstan/Siberia in the Permian. This was followed by the suturing of Sibumasu and Qiangtang to Cathaysialand in the
Song, Fengfei; Zhou, Tianjun; Qian, Yun
In this study, we examined the responses of East Asian Summer Monsoon (EASM) to natural (solar variability and volcanic aerosols) and anthropogenic (greenhouse gasses and aerosols) forcings simulated in the 17 latest Coupled Model Intercomparison Program phase 5 (CMIP5) models with 105 realizations. The observed weakening trend of low-level EASM circulation during 1958-2001 is partly reproduced under all-forcing runs. A comparison of separate forcing experiments reveals that the aerosol-forcing plays a primary role in driving the weakened low-level monsoon circulation. The preferential cooling over continental East Asia caused by aerosol affects the monsoon circulation through reducing the land-sea thermal contrast and results in higher sea level pressure over northern China. In the upper-level, both natural-forcing and aerosol-forcing contribute to the observed southward shift of East Asian subtropical jet through changing the meridional temperature gradient.
Akimoto, H.; Li, J.; Wang, Z.; Yamaji, K.; Pochanart, P.; Ohara, T.; Uno, I.; Gao, C.; Wang, X.; Tanimoto, H.; Kurokawa, J.
Form satellite observational data, east-central China covering the North China Plain (NCP) and Yanzi Delta (YZD) has been identified as the most widely spread source area of air pollutants in the East Asian Pacific region. In order to quantify transport and chemical production of ozone in this region, both of observational and modeling studies in both of source and outflow region are necessary. In the present study, we investigated the budgets of ozone over East Asia by using regional chemical transport models (NAQPMS and CMAQ) based on observations at newly founded three mountain sites (Mt. Tai, Hua and Huang) in east-central China, and several sites from EANET and regional WMO/GAW. The observations show that a striking pattern of two sharp high ozone peaks in May-June and September-October at the three mountain sites. The budget analysis by the model confirms that maximum of net photochemical ozone production reaches 31.8, 15.1 and 11.4 ppb/day at Mt. Tai, Hua and Huang, respectively. The net chemical production dominates the formation of ozone maximum at Mt. Tai and Hua in June, and the importing transport also plays a comparable importance at Mt. Huang. In the outflow region at Oki, Japan, transport of ozone produced by East Asian emissions accounts up to 21 ppb in summer but less than 3 ppb in winter agreeing with the model analysis. The contribution of ozone due to East Asian emission is the largest (53.6%) in July-August, and somewhat smaller in May-June (34.0%) and September-October (30.7%) on the transect between Japan and the Asian continent.
Li, Yana; Yang, Song
This study investigates the interannual variation and feedback attributions of the East Asian Winter Monsoon for the period of 1979-2013. The variations of winter mean surface air temperature are dominated by two distinct principal modes, which account for 70.9% of the total variance. The interannual variation of the northern mode features high correlations with the variations of the Arctic Oscillation, the Siberia High, and the tropoical Indian Ocean Dipole, while the southern mode is strongly linked to the East Asia trough and the atmospheric circulation over the northwestern Pacific. To find the main factors which affect the two different modes, this study decomposes the surface air temperature interannual variation into various feedback attributions by applying a climate feedback-response analysis method. The results indicate that the surface cooling associated with the northern mode is mainly contributed by the feedback processes of atmospheric dynamics, cloud, and sensible heating. For the southern mode, the surface cooling is mainly attributed to the atmospheric dynamic process, sensible heating, and water vapor, while the oceanic dynamics and heat storage process induces a negative effect that warms the surface.
The Japan/East Sea (JES), a part of East Asian Marginal Seas, is a semi-enclosed sea located upstream of the North Pacific storm track. SST variability in the JES and the ensuing air-sea process are important for local winter atmospheric condition. It is believed that the marginal sea processes also influence the storm track evolution far downstream. Dynamical processes leading to local and remote atmospheric circulation response to leading JES SST anomaly patterns are investigated using a hemispheric WRF atmospheric model with two-way multi-nesting capabilities. The atmospheric circulation in direct contact with anomalous diabatic forcing exhibits a linear baroclinic response with respect to sign of SST anomalies; that is, the northwesterly surface wind is strengthened (weakened) and the local precipitin is enhanced (reduced) over the warm (cold) SSTs. The linearity of the local response confirms the importance of fine-scale SST patterns to the predictability of regional weather and climate conditions. The downstream response, in contrast, is nonlinear, with an enhanced intraseasonal equivalent barotropic ridge emerging in the Gulf of Alaska irrespective of the polarity of JES SST anomalies. This downstream blocking high response is maintained by the positive low-frequency height tendency due to transient eddy vorticity flux convergence associated with altered storm track. The significant remote response in the North Pacific storm track and the blocking suggests that the marginal sea process is an active part of the North Pacific climate variability.
Sano, K; Shiina, T; Kohara, S; Yanagiya, K; Hosomichi, K; Shimizu, S; Anzai, T; Watanabe, A; Ogasawara, K; Torii, R; Kulski, J K; Inoko, H
Cynomolgus macaques (Macaca fascicularis, Mafa), alias the crab-eating monkeys or long-tailed macaques, live across a vast range of South-East Asia. These non-human primates have emerged as important animal models in infectious and chronic diseases and transplantation studies, necessitating a more extensive characterization of their major histocompatibility complex polymorphic regions. The current information on the polymorphic variation or diversity of the Mafa-DPB1 locus is largely limited in comparison with the more commonly studied rhesus macaque DPB1 locus. In this article, to better elucidate the degree and types of polymorphisms and genetic differences of Mafa-DPB1 locus among three South-East Asian populations and to investigate how the allele differences between macaques and humans might affect their respective immune responses, we identified 40 alleles within exon 2 of the Mafa-DPB1 locus by DNA sequencing using 217 individuals. We also performed evolutionary and population analyses using these sequences to reveal some population-specific alleles and trans-species allelic conservation between the cynomolgus macaques and the rhesus macaques. Of the 40 new alleles, eight belong to a newly identified lineage group not previously found in the rhesus macaque species. This allele information will be useful for medical researchers using the cynomolgus macaques in disease and immunological studies.
Yao, Suxiang; Sun, Qingfei; Huang, Qian; Chu, Peng
East Asia is known for its monsoon characteristics, but little research has been performed on the intraseasonal time scale of the East Asian winter monsoon (EAWM). In this paper, the extended reanalysis (ERA)-Interim sub-daily data are used to study the surface air temperature intraseasonal oscillation (ISO) of the EAWM. The results show that the air temperature (2-m level) of the EAWM has a dominant period of 10-30 days. Lake Baikal and south China are the centers of the air temperature ISO. An anomalous low frequency (10-30-day filtered) anticyclone corresponds to the intraseasonal cold air. The 10-30-day filtered cold air spreads from Novaya Zemlya to Lake Baikal and even to South China. The ISO of the Arctic Oscillation (AO) index influences the temperature of the EAWM by stimulating Rossby waves in middle latitude, causing meridional circulation, and eventually leads to the temperature ISO of the EAWM. RegCM4 has good performance for the simulation of the air temperature ISO. The simulated results indicate that the plateau is responsible for the southward propagation of the intraseasonal anticyclone. The anticyclone could not reach South China when there was no plateau in western China and its upper reaches.
Ning, Chao; Yan, Shi; Hu, Kang; Cui, Yin-Qiu; Jin, Li
The human Y-chromosome haplogroup O-M134 is one of the most abundant paternal lineages in East Asian populations, comprising ~13% of Han Chinese males, and also common in Kazakh, Korean, Japanese, Thai and so on. Despite its considerable prevalence, its current substructure is poorly resolved with only one downstream marker (M117) previously investigated. Here we address this deficiency by investigating some single-nucleotide polymorphisms (SNPs) previously reported being potentially associated with O-M134 based on high-throughput DNA-sequencing data. Using a panel of 1301 Chinese males we first identified 154 haplogroup O-M134 subjects. We then investigated the phylogenetic structure within this haplogroup using 10 SNPs (F444, F629, F3451, F46, F48, F209, F2887, F3386, F1739 and F152). Two major branches were identified, O-M117 and O-F444 and the latter was further divided into two main subclades, O-F629 and O-F3451, accounting for 10.84 and 0.92% of the Han Chinese, respectively. This update of O-M134 diversification permits better resolution of male lineages in population studies of East Asia. PMID:26306641
Ma, Ronald CW; Chan, Juliana CN
There is an epidemic of diabetes in Asia. Type 2 diabetes develops in East Asian patients at a lower mean body mass index (BMI) compared with those of European descent. At any given BMI, East Asians have a greater amount of body fat and a tendency to visceral adiposity. In Asian patients, diabetes develops at a younger age and is characterized by early β cell dysfunction in the setting of insulin resistance, with many requiring early insulin treatment. The increasing proportion of young-onset and childhood type 2 diabetes is posing a particular threat, with these patients being at increased risk of developing diabetic complications. East Asian patients with type 2 diabetes have a higher risk of developing renal complications than Europeans and, with regard to cardiovascular complications, a predisposition for developing strokes. In addition to cardiovascular–renal disease, cancer is emerging as the other main cause of mortality. While more research is needed to explain these interethnic differences, urgent and concerted actions are needed to raise awareness, facilitate early diagnosis, and encourage preventive strategies to combat these growing disease burdens. PMID:23551121
Some progresses in impacts of Western Pacific Ocean (WPO) on East Asian monsoon and stratosphere climate are reviewed from the following aspects. (1) Impact of the IPOD (a cross-basin dipole pattern of SSTA variability between the Indo-Pacific warm pool (IPWP) and North Pacific Ocean) on the East Asian summer monsoon (EASM).The IPOD exhibits a considerable correlation with the EASM. In summers with a positive IPOD phase, the western Pacific subtropical high (WPSH) weakens and shrinks with WPSH ridge moving northwards, which favours an intensified EASM and a decrease in summer rainfall in the Yangtze River valley, and vice versa. (2) TheIndo-Western Pacific convection oscillation (IPCO),which is an out-of-phase fluctuation in convection anomalies between the north Indian Ocean and the western North Pacific region,is closely related to the EASM.Negative IPCO phases, which exhibit an enhanced convection over the north Indian Ocean and a suppressed convection over the western North Pacific, favor a weakened EASM and an increase of summer rainfall in the Yangtze River valley with the joint actions of the stronger than normal Ural and Okhotsk blocking highs and the subtropical western Pacific high, and vice versa.(3) Asymmetric influence of the two types of ENSO on summer rainfall in China. The two types of ENSO have asymmetric impacts on summer rainfall over the Yangtze River Valley. The relation between summer rainfall over this valley and the cold tongue (CT) El Niño is significantly positive, while the relation with the CT La Niña is not significant. The negative phase of the warm pool (WP) ENSO has a significant positive influence, whereas no significant relation with the positive phase. They indicated that this asymmetric response of the EASM is likely to be linked to the different spatial patterns of the two types of ENSO.(4) Linkage between recent winter precipitation increase in the middle-lower Yangtze River valley (MLY) since the late 1970s andwarming in the
Kong, W.; Chiang, J. C. H.
The Holocene East Asian Summer Monsoon (EASM) was characterized by a trend to weaker monsoon intensity paced by orbital insolation. Here, we attribute the stronger EASM intensity in the early-mid Holocene to changes in the timing of the transition between the EASM seasonal stages - Spring, pre Mei- Yu, Mei-Yu, and Summer - during that time. Following the recent 'jet transition hypothesis' (Chiang et al., 2015), we explore the role of north-south displacement of the westerlies relative to the Tibetan Plateau that is hypothesized to control the downstream EASM seasonality changes across the Holocene. To this end, we analyze model simulations of the Holocene EASM, compare the simulated Holocene climate with the paleodata observations, and examine the role of atmospheric circulation and specifically the westerlies in modulating the East Asia summer climate. The PMIP3 climate model simulations suggest that, compared to the pre-industrial, the Mei-Yu onset and the transition from Mei-Yu to Summer rainfall occur earlier in the mid-Holocene. The advanced seasonal rainfall transition is accompanied by the weakened and northward-shifted upstream westerlies. In our atmospheric general circulation model (coupled to a slab ocean) simulations of various time periods across the Holocene (9ka, 6ka, 3ka, and pre-industrial), we quantitatively show that the timing and the length of each rainfall stage are closely related to the jet position over East Asia. We also show that the simulated changes in the maximum annual rainfall band and dust emission over East Asia largely agree with the paleo-proxy observations. In addition, we find that changes to the seasonal rainfall transitions, latitudinal westerly position, and stationary eddy activity over East Asia co-vary across the Holocene. In particular, we argue that the changes in the rainfall seasonal transitions are tied to an altered stationary wave pattern, resembling today's the so-called 'Silk Road Pattern', riding along the
Menking, J. A.; Kaspari, S.; Osterberg, E. C.; Fisher, D.
Black carbon (BC), an aerosol created from the incomplete combustion of fossil and biofuels, absorbs sunlight causing warming in the atmosphere and cooling at the surface. BC deposited on snow and ice reduces the surface albedo, accelerating seasonal snowmelt and glacier retreat and influencing the regional water cycle and climate. Estimates place East Asia as the top BC producer worldwide. Recent studies suggest that increases in East Asian BC related to industrialization have influenced Asian climate by altering temperatures and the timing and magnitude of precipitation. East Asian BC emissions have been estimated using fossil fuel inventories, but observational data is needed to constrain the timing and magnitude of recent BC emissions changes in order to better assess the role of BC in recent climate change. Here we present a time series of East Asian atmospheric BC that spans 1750-1999 AD that was developed using an ice core collected at the Prospector-Russell (PR) Col on Mt. Logan, Yukon Territory, Canada. The PR Col ice core is ideal for developing a record of East Asian BC emissions because the Mt. Logan summit has been shown to capture Asian emissions transported across the Pacific Ocean. The Mt. Logan record shows increases in BC concentration occurring in the early 1980's related to the recent industrialization of East Asian nations. We utilize the BC record from Mt. Logan (1) for comparison with estimated East Asian emissions inventories, and (2) to assess the role of BC in recent climate change with respect to the timing and magnitude of changes in East Asian BC emissions.
Borucki, Monica K.; Lao, Victoria; Hwang, Mona; Gardner, Shea; Adney, Danielle; Munster, Vincent; Bowen, Richard; Allen, Jonathan E.
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging human pathogen related to SARS virus. In vitro studies indicate this virus may have a broad host range suggesting an increased pandemic potential. Genetic and epidemiological evidence indicate camels serve as a reservoir for MERS virus but the mechanism of cross species transmission is unclear and many questions remain regarding the susceptibility of humans to infection. Deep sequencing data was obtained from the nasal samples of three camels that had been experimentally infected with a human MERS-CoV isolate. A majority of the genome was covered and average coverage was greater than 12,000x depth. Although only 5 mutations were detected in the consensus sequences, 473 intrahost single nucleotide variants were identified. Many of these variants were present at high frequencies and could potentially influence viral phenotype and the sensitivity of detection assays that target these regions for primer or probe binding. PMID:26790002
Borucki, Monica K.; Lao, Victoria; Hwang, Mona; Gardner, Shea; Adney, Danielle; Munster, Vincent; Bowen, Richard; Allen, Jonathan E.
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging human pathogen related to SARS virus. In vitro studies indicate this virus may have a broad host range suggesting an increased pandemic potential. Genetic and epidemiological evidence indicate camels serve as a reservoir for MERS virus but the mechanism of cross species transmission is unclear and many questions remain regarding the susceptibility of humans to infection. Deep sequencing data was obtained from the nasal samples of three camels that had been experimentally infected with a human MERS-CoV isolate. A majority of the genome was covered and average coverage was greater than 12,000x depth. Although only 5 mutations were detected in the consensus sequences, 473 intrahost single nucleotide variants were identified. Lastly, many of these variants were present at high frequencies and could potentially influence viral phenotype and the sensitivity of detection assays that target these regions for primer or probe binding.
Fremme, Astrid; Sodemann, Harald
The rainfall of the East Asian Monsoon is of key importance for livelihoods in the densely populated area of China, Japan and Korea. The interplay of many factors, including land surface processes, makes monsoon precipitation difficult to predict. To contribute to improved precipitation prediction we investigate the atmospheric mechanisms importing moisture to the region. In previous studies moisture transport has mainly been analysed by examining a combination of temperature, pressure, winds and water vapour content. However this has been done without linking precipitation to its moisture sources directly. In this project we use the Lagrangian particle dispersion model FLEXPART and the diagnostic tool WaterSip to analyse ERA Interim reanalysis data to obtain a link between precipitation and its moisture sources. The total atmospheric mass is subdivided into millions air parcels, which are traced backwards for 20 days for each rainfall event in the 34 year ERA-Interim period. Specific humidity changes are interpreted as evaporation and precipitation in the area beneath the parcel with the help of a sophisticated accounting method related to target precipitation. Results on the relationship between source and sink areas reflect changes in the conditions of the source regions and in moisture transport. We investigate the moisture transport mechanisms for both seasonal and inter-annual variations during the study period 1979-2013. Preliminary results show that the sources for precipitation in the Yangtze River Valley (YRV) in China have a clear seasonal cycle in terms of location and evaporation conditions. Land areas outside the YRV Region contribute most of the moisture. The second largest source is inside the YRV region itself. For monthly means the sum of all direct oceanic sources rarely exceeds 20%. Recycling of moisture from land surfaces outside the target regions therefore seems to play a pivotal role in the East Asian Monsoon's moisture budget. Contrasting
Yim, S. Y.; Wang, B.; Xing, W.; Kim, H. K.
East Asian summer monsoon (EASM) rainfall has a profound influence on the lives of billions of people. The seasonal prediction of the EASM rainfall, however, has long been an outstanding challenge in climate science. Traditional seasonal forecast of EASM deals with JJA mean rainfall anomalies, which may not be the best strategy because the EASM rainy season is typically from May to August and pronounced differences exist between early summer (May-June, MJ) and peak summer (July-August, JA): both climatological mean states and the principal modes of interannual variability exhibit distinct spatial and temporal structures. The present study explores the sources and limit of the predictability of the early and peak summer rainfall over the East Asian (EA) region. Since the climate models' seasonal forecasts have rather limited skills, it is important to find the causes of the low skills, to improve seasonal prediction, and to better estimate the predictability of EASM rainfall. We address this issue by applying predictable mode analysis method. Four empirical modes of variability for peak summer rainfall are identified: (a) an equatorial western Pacific-EA teleconnection mode, (b) a western Pacific subtropical high-dipole feedback mode, (c) a central Pacific-ENSO mode, and (d) a Eurasian wave train mode. These modes are named according to the major sources of predictability. Based on the understanding of predictability sources for each mode, a suite of physical-empirical (P-E) models is established to predict the four leading principal components (PCs). All four modes can be predicted with significant cross-validated correlation skills(0.59-0.65). Using the predicted PCs and the corresponding observed spatial patterns, a 35-year cross-validated hindcast over the EA yields a domain-averaged TCC skill is 0.37, which is higher than the MME hind cast skill (0.13). The estimated potential attainable pattern correlation coefficient skill averaged over the entire domain is
Sun, Xuguang; Yang, Xiuqun; Greatbatch, Richard; Park, Wonsun
In observations, the leading mode of variability of East Asian summer monsoon (EASM) features enhanced precipitation along the Yangtze River Valley, and mainly occurs in El Nino decaying summer (Sun et al. 2010). Kiel Climate Model (KCM) developed by Park et al. (2009) in GEOMAR, Germany is capable of reproducing these EASM characteristics in its 1000-year twentieth century equivalent (20C) control simulation. Moreover, consistent with the results of ERA-40 reanalysis data, the 1000-year 20C simulation of KCM also demonstrates an unstable relationship of EASM and ENSO, and the reason is particularly investigated in this study. The simulated El Nino events are selected and grouped into 4 categories according to their intensities and their relationships with EASM, i.e., Strong ENSO Strong Relation (SESR), Strong ENSO Weak Relation (SEWR), Weak ENSO Strong Relation (WESR) and Weak ENSO Weak Relation (WEWR). Their comparisons indicate that in situations of strong EASM-ENSO relationship, the suppressed precipitation in the northwest Pacific is more significant, so are the major components of EASM, such as western Pacific anticyclone (WPA) anomaly, the western Pacific subtropical high (WPSH), and the East Asian subtropical westerly jet (EASWJ) regardless of strong or weak ENSO, and vice versa. As for the strong ENSO, the robust EASM-ENSO relation mainly comes from the mid-eastern tropical Pacific where obvious large positive ENSO SST anomalies exist. However, it is primarily from the much warmer tropical Indian Ocean for the weak ENSO. Furthermore, correlation results show that EASM-ENSO relationship is getting more robust when much warmer interdecadal SST anomalies appear in the tropical Indian Ocean, tropical Atlantic Ocean and mid-western off-equatorial Pacific Ocean, which causes remarkably reduced convection and precipitation over the western Pacific, and then enhanced WPA anomaly, WPSH and EASWJ. Finally, the interdecadal changes of oceanic and atmospheric basic
Cheng, Shao-Yi; Suh, Sang-Yeon; Morita, Tatsuya; Oyama, Yasuhiro; Chiu, Tai-Yuan; Koh, Su Jin; Kim, Hyun Sook; Hwang, Shinn-Jang; Yoshie, Taeko; Tsuneto, Satoru
Abstract The primary aim of this study was to explore common beliefs and practices when death is approaching in East-Asian countries. A cross-sectional survey was performed involving palliative care physicians in Japan, Korea, and Taiwan. Measurement outcomes were physician-perceived frequencies of the following when patient death was approaching: (1) reluctance to take part in end-of-life discussions, (2) role of family members, (3) home death, and (4) circumstances surrounding death. A total of 505, 211, and 207 responses were obtained from Japanese, Korea, and Taiwan physicians, respectively. While 50% of the Japanese physicians reported that they often or very often experienced families as being reluctant to discuss end-of-life issues, the corresponding figures were 59% in Korea and 70% in Taiwan. Two specific reasons to avoid end-of-life discussion, “bad things happen after you say them out loud” and “a bad life is better than a good death” were significantly more frequently observed in Taiwan. Prioritizing the oldest of the family in breaking bad news and having all family members present at the time of death were significantly more frequently observed in Korea and Taiwan. Half of Taiwanese physicians reported they often or very often experienced the patients/family wanted to go back home to die because the soul would not be able to return from the hospital. In all countries, more than 70% of the physicians reported certain family members were expected to care for the patient at home. At the time of death, while no Japanese physicians stated that they often experienced patients wanted a religious person to visit, the corresponding figure in Korean and Taiwan was about 40%. Uncovered expression of emotion was significantly frequently observed in Korean and Taiwan, and 42% of the Japanese physicians reported family members cleaned the dead body of the patient themselves. There seem to be significant intercountry differences in beliefs and practices when
Jiang, Yiquan; Liu, Xiaohong; Yang, Xiuqun; Wang, Minghuai
The impact of anthropogenic aerosol on the East Asian summer monsoon (EASM) is investigated with NCAR CAM5, a state-of-the-art climate model with aerosol’s direct and indirect effects. Results indicate that anthropogenic aerosol tends to cause a weakened EASM with a southward shift of precipitation in East Asia mostly by its radiative effect. Anthropogenic aerosol induced surface cooling stabilizes the boundary layer, suppresses the convection and latent heat release in northern China, and reduces the tropospheric temperature over land and land-sea thermal contrast, thus leading to a weakened EASM. Meanwhile, acting as cloud condensation nuclei (CCN), anthropogenic aerosol can significantly increase the cloud droplet number concentration but decrease the cloud droplet effective radius over Indochina and Indian Peninsulas as well as over southwestern and northern China, inhibiting the precipitation in these regions. Thus, anthropogenic aerosol tends to reduce Southeast and South Asian summer monsoon precipitation by its indirect effect.
Ding, Qiliang; Hu, Ya; Xu, Shuhua; Wang, Jiucun; Jin, Li
Studies of the Neanderthal and Denisovan genomes demonstrate archaic hominin introgression in Eurasians. Here, we present evidence of Neanderthal introgression within the chromosome 3p21.31 region, occurring with a high frequency in East Asians (ranging from 49.4% to 66.5%) and at a low frequency in Europeans. We also detected a signal of strong positive selection in this region only in East Asians. Our data indicate that likely candidate targets of selection include rs12488302-T and its associated alleles--among which four are nonsynonymous, including rs35455589-G in HYAL2, a gene related to the cellular response to ultraviolet-B irradiation. Furthermore, suggestive evidence supports latitude-dependent selection, implicating a role of ultraviolet-B. Interestingly, the distribution of rs35455589-G suggests that this allele was lost during the exodus of ancestors of modern Eurasians from Africa and reintroduced to Eurasians from Neanderthals.
Areepattamannil, Shaljan; Caleon, Imelda S
The authors examined the relationships of cognitive (i.e., memorization and elaboration) and metacognitive learning strategies (i.e., control strategies) to mathematics achievement among 15-year-old students in 4 high-performing East Asian education systems: Shanghai-China, Hong Kong-China, Korea, and Singapore. In all 4 East Asian education systems, memorization strategies were negatively associated with mathematics achievement, whereas control strategies were positively associated with mathematics achievement. However, the association between elaboration strategies and mathematics achievement was a mixed bag. In Shanghai-China and Korea, elaboration strategies were not associated with mathematics achievement. In Hong Kong-China and Singapore, on the other hand, elaboration strategies were negatively associated with mathematics achievement. Implications of these findings are briefly discussed.
Liu, J.; Mauzerall, D. L.; Horowitz, L. W.
We analyze the effect of varying East Asian (EA) sulfur emissions on sulfate concentrations in the Northern Hemisphere, using a global coupled oxidant-aerosol model (MOZART-2). We conduct a base and five sensitivity simulations, in which sulfur emissions from each continent are tagged, to establish the source-receptor (S-R) relationship between EA sulfur emissions and sulfate concentrations over source and downwind regions. We find that from west to east across the North Pacific, EA sulfate contributes approximately 80%-20% of sulfate at the surface, but at least 50% at 500 hPa. In addition, EA SO2 emissions account for approximately 30%-50% and 10%-20% of North American background sulfate over the western and eastern US, respectively. The contribution of EA sulfate to the western US at the surface is highest in MAM and JJA, but is lowest in DJF. Reducing EA SO2 emissions will significantly decrease the spatial extent of the EA sulfate influence over the North Pacific both at the surface and at 500 mb in all seasons, but the extent of influence is insensitive to emission increases, particularly in DJF and JJA. We find that EA sulfate concentrations over most downwind regions respond nearly linearly to changes in EA SO2 emissions, but sulfate concentrations over the EA source region increase more slowly than SO2 emissions, particularly at the surface and in winter, due to limited availability of oxidants (mostly H2O2). We find that similar estimates of the S-R relationship for trans-Pacific transport of EA sulfate would be obtained using either sensitivity or tagging techniques. Our findings suggest that future changes in EA sulfur emissions may cause little change in the sulfate induced health impact over downwind continents but SO2 emission reductions may significantly reduce the sulfate related climate cooling over the North Pacific and the United States.
Xu, B.; Shi, C.; Xie, P.
During the last three years, the East Asian Multi-Satellite Integrated Precipitation (EMSIP) was developed at China Meteorological Administration (CMA) National Meteorological Information Center (NMIC), partially through cooperation with NOAA/CPC. IR TBB data from the FY-2 Geostationary satellite and PMW rain rate retrievals from FY-3B, TRMM, NOAA-18/19, METOP-A/B, and DMSP-F16/17/18 were integrated to produce high-resolution satellite precipitation estimates over East Asia. While the current version of the product relies on retrievals from TMI to inter-calibrate inputs from other platforms, work is underway to improve the quality of EMSIP using retrievals from the GMI. As an important step to infuse the GMI into our integration system, a comprehensive evaluation is performed for the precipitation retrievals from the GMI and the 8 other above mentioned PMW sensors with an emphasis on their performance on detecting and quantifying light rain and snowfall. PMW retrievals are compared against in situ measurements from a dense network of automatic rain gauges over China for a cold season month (January 2015). Impacts of infusing GMI precipitation retrievals into our integrated estimates are examined. Results showed improved capacity of the current version GMI retrievals in capturing light rain and snowfall than other sensors for the test period over China. The FAR score, however, is about the same as that for the TMI's. Partially due to the limited test period, only minor improvements are observed in the EMSIP through infusing GMI. Compared with CMORPH, the correlation of EMSIP and the GMI infused EMSIP is still a little lower over whole china, but sometimes over Tibet Plateau the correlation of EMSIP+GMI is higher than EMSIP and CMORPH.
Hu, Chundi; Yang, Song; Wu, Qigang
Extreme cold events occur frequently in China. The authors define a representative yet simple index to reveal the monthly changes in China winter temperature associated with the East Asian winter monsoon (EAWM), which is represented by both the leading empirical orthogonal function (EOF) mode and the country-mean temperature index of Chinese 160 gauge stations. A combined technique of correlation and multivariate EOF (Corr-MVEOF) analyses is applied to capture the dominant coupled patterns of EAWM circulation system. Based on the atmospheric circulation features captured by the leading Corr-MVEOF mode, a new EAWM index referred to as CNWMI is derived by using a stepwise regression analysis. The CNWMI highlights the importance of (1) the Mongolia-Siberian High (MSH) and its southward expansion and (2) the Asia-wide meridional dipole anomaly of 500 hPa geopotential height. Compared with the 27 existing EAWM indices, the CNWMI not only best represents the leading modes of both EAWM circulation system and China winter temperature, but also reasonably tracks the intraseasonal-to-interdecadal variations of EAWM so that the monthly intensity of EAWM can be monitored conveniently. In particular, the Aleutian low (AL) is not strongly related to the MSH and may not be responsible for the variability of EAWM/MSH. Moreover, the indices that are highly correlated with the temperature over southern East Asia do not show significant relationships with the AL, which is different from the conventional concept that a strong EAWM/MSH is linked to a deepened AL. In contrast, the anomalous Australia-Maritime Continent low is in good agreement with the variation of EAWM/MSH.
Nakamura, H.; Machimura, T.; Ogawa, S.; Kosaka, Y.; Nishii, K.; Miyasaka, T.
The East Asian summer monsoon fluctuates from its climatological activity on monthly and interannual time scales, and the most dominant pattern of the variability is known as the Pacific-Japan (PJ) pattern. Characterized by a meridional teleconnection in anomalous activity of the Meiyu/Baiu rainband, tropical storms and a surface subtropical anticyclone (the Bonin High) in between, the PJ pattern exerts substantial influence on summertime climatic conditions over East Asia and the western North Pacific. Despite the recent warming trend observed in its background state, no assessment thus far has been made on how substantially the PJ has undergone, if any, multi-decadal modulations in its structure and/or dominance. Through an EOF analysis applied to a new dataset of global atmospheric reanalysis (JRA-55), the predominance of the PJ pattern is confirmed as being extracted in the leading EOF of lower-tropospheric monthly vorticity anomalies over 55 recent years. Both efficient barotropic/baroclinic energy conversion from the climatological-mean state and efficient generation of available potential energy through anomalous convective activity over the tropical western Pacific are shown to be essential for the maintenance of the monthly atmospheric anomalies of the PJ pattern over the entire 55-year period. At the same time, however, the same EOF analysis as above but applied separately to each of the sub-periods reveals a distinct signature of long-term modulations in amplitude and thus the dominance of the PJ pattern. While being extracted in the first EOF up to the 1980s, the PJ pattern is extracted in the second EOF in the period since the 1990s with marked reductions in both the variance fraction explained and the efficiency of energy conversion/generation. The resultant modulations of the summertime meridional teleconnection are also discussed with implications for future changes.
Persad, G.; Paynter, D.; Ming, Y.; Ramaswamy, V.
Absorbing aerosols, by attenuating shortwave radiation within the atmosphere and reemitting it as longwave radiation, redistribute energy both vertically within the surface-atmosphere column and horizontally between polluted and unpolluted regions. East Asia has the largest concentrations of anthropogenic absorbing aerosols globally, and these, along with the region's scattering aerosols, have both reduced the amount of solar radiation reaching the Earth's surface regionally ("solar dimming") and increased shortwave absorption within the atmosphere, particularly during the peak months of the East Asian Summer Monsoon (EASM). We here analyze how atmospheric absorption and surface solar dimming compete in driving the response of EASM circulation to anthropogenic absorbing aerosols, which dominates, and why—issues of particular importance for predicting how the EASM will respond to projected changes in absorbing and scattering aerosol emissions in the future. We probe these questions in a state-of-the-art general circulation model (GCM) using a combination of realistic and idealized aerosol perturbations that allow us to analyze the relative influence of absorbing aerosols' atmospheric and surface-driven impacts on EASM circulation. In combination, our results make clear that, although absorption-driven dimming has a less detrimental effect on EASM circulation than purely scattering-driven dimming, aerosol absorption is still a net impairment to EASM strength when both its atmospheric and surface effects are considered. Because atmospheric heating is not efficiently conveyed to the surface, the surface dimming and associated cooling from even a pure absorber is sufficient to counteract its atmospheric heating, resulting in a net reduction in EASM strength. These findings elevate the current understanding of the impacts of aerosol absorption on the EASM, improving our ability to diagnose EASM responses to current and future regional changes in aerosol emissions.
Kang, Daehyun; Lee, Myong-In
This study examined the forecast skill for the East Asian Winter Monsoon (EAWM) using the following state-of-the-art dynamical seasonal prediction systems: CanCM3, CanCM4, CFSv2, CM2.1, and GEOS-5. To assess the prediction skills and the associations with ENSO teleconnections of these systems, long-term seasonal hindcast data sets for 28 years (1983-2010) were investigated. Observational data indicated that the ENSO-EAWM connection strengthened in a recent period (1997-2010; r = -0.84) compared with that in an earlier period (1983-1996; r = -0.44). For the recent period, a practical level of prediction skill for the EAWM index was retained by CFSv2 and GEOS-5 for the lead time of 2 months or longer, with these models showing a realistic ENSO-EAWM relationship throughout the Western Pacific Warm Pool with east-west dipole anomalies of precipitation induced by ENSO. The prediction skill of the other models was poor, even for lead times of zero to 1 month, with weak ENSO-EAWM relationships and errant north-south dipole anomalies of precipitation associated with ENSO. A large model spread was also found consistently in the CMIP5 AMIP and the Historical simulations by 14 models of the spatial pattern of equatorial Pacific precipitation anomalies associated with ENSO and the effect on the ENSO-EAWM relationship. Based on this study, the accurate prediction of EAWM should be linked with a realistic representation of the convection response in the equatorial Pacific by ENSO and the teleconnection to EAWM.
Hao, N.; Ding, A.; Valks, P.; Safieddine, S.; Clerbaux, C.; Trautmann, T.
Air pollution is one of the most important environmental problems in developing Asian countries like China. Due to huge consumption of fossil fuels and rapid increase of traffic emissions in the past decades, many regions in China have been experiencing heavy air pollution. In China, studies showed that the East Asian monsoon plays a significant role in characterizing the temporal variation and spatial patterns of air pollution, since monsoon is a major atmospheric system affecting air mass transport, convection, and precipitation. Publicly available in situ observations cannot provide sufficient spatial coverage and high consistence in data quality for a long-term period. Therefore, knowledge gaps still exist in the understanding of Asian monsoon impact on the air quality in China under the background of global climate change. Satellite retrievals with high spatial coverage and high consistence for a long period can well document the change of air pollution with monsoon. We apply multi-platform satellite observations by the GOME, SCIAMACHY, GOME-2, IASI, GOMOS, MIPAS and MOPITT instruments to analyze tropospheric ozone and CO, precursors of ozone (NOx, HCHO and CH4) and other related trace gases over China. The potential of using the current generation of satellite instruments to monitor air quality changes caused by the East Asian monsoon circulation will be presented. Preliminary comparison results between satellite measurement and limited but valuable ground-based and aircraft measurements will also be showed.
Lee, Ji Hyun; Ahn, Sung Gyun; Park, Bonil; Park, Sang Wook; Kang, Yong Seok; Lee, Jun-Won; Youn, Young Jin; Ahn, Min-Soo; Kim, Jang-Young; Yoo, Byung-Su; Lee, Seung-Hwan; Yoon, Junghan
Background/Aims: Newer P2Y12 inhibitors, such as prasugrel and ticagrelor, have greater antiplatelet efficacy but may increase the risk of bleeding. In this study, we compared the pharmacodynamic efficacy of prasugrel and ticagrelor in East Asian patients with acute coronary syndrome (ACS). Methods: We selected 83 ACS patients undergoing percutaneous coronary intervention who were discharged with 90 mg ticagrelor twice daily (n = 24), 10 mg prasugrel daily (n = 39) or 5 mg prasugrel daily (n = 20). After 2 to 4 weeks, on-treatment platelet reactivity (OPR) was assessed in terms of P2Y12 reaction units (PRUs) using the VerifyNow P2Y12 assay (Accumetrics). We compared East Asian (85 < PRU ≤ 275) and Caucasian (85 < PRU ≤ 208) criteria for assessing the therapeutic window of OPR. Results: OPR was lowest in the ticagrelor group, followed by the 10 mg prasugrel and 5 mg prasugrel groups (49.1 ± 29.9 vs. 83.7 ± 57.1 vs. 168.5 ± 60.8, respectively; p < 0.001). The 5 mg prasugrel group had the highest proportion of patients with OPR values within the therapeutic window, followed by the 10 mg prasugrel and ticagrelor groups (90.0% vs. 46.2% vs. 12.5%, respectively; p < 0.001 for East Asian criteria; 60.0% vs. 43.6% vs. 12.5%, respectively; p < 0.001 for Caucasian criteria). Conclusions: Short-term administration of 5 mg prasugrel facilitated maintenance within the therapeutic window of OPR compared with the 10 mg prasugrel and ticagrelor groups. Thus, 5 mg prasugrel daily may be the optimal antiplatelet regimen for stabilized East Asian ACS patients. PMID:26354056
Hasunuma, Tomoko; Tohkin, Masahiro; Kaniwa, Nahoko; Jang, In‐Jin; Yimin, Cui; Kaneko, Masaru; Saito, Yoshiro; Takeuchi, Masahiro; Watanabe, Hiroshi; Yamazoe, Yasushi; Uyama, Yoshiaki
Aim To examine whether strict control of clinical trial conditions could reduce apparent differences of pharmacokinetic (PK) parameters among ethnic groups. Methods Open‐label, single dose PK studies of moxifloxacin, simvastatin and meloxicam were conducted in healthy male subjects from three East Asian populations (Japanese, Chinese and Koreans) and one Caucasian population as a control. These three drugs were selected because differences in PK parameters have been reported, even though the backgrounds of these East Asian populations are similar. Moxifloxacin (400 mg) was administered orally to 20 subjects, and plasma and urine levels of moxifloxacin and its metabolite (M2) were measured. Simvastatin (20 mg) was given to 40 subjects, and plasma levels of simvastatin and simvastatin acid were measured. Meloxicam (7.5 mg) was given to 30 subjects and its plasma concentration was determined. Intrinsic factors (polymorphism of UGT1A1 for moxifloxacin, SLCO1B1 for simvastatin, and CYP2C9 for meloxicam) were also examined. Results AUCinf values for moxifloxacin, simvastatin and meloxicam showed no significant differences among the East Asian groups. Cmax values of moxifloxacin and simvastatin, but not meloxicam, showed significant differences. There were no significant differences of data for M2 or simvastatin acid. Genetic analysis identified significant differences in the frequencies of relevant polymorphisms, but these differences did not affect the PK parameters observed. Conclusions Although there were some differences in PK parameters among the three East Asian groups, the present study performed under strictly controlled conditions did not reproduce the major ethnic differences observed in previous studies. PMID:26774055
Yi Zhang; Sperber, K.; Boyle, J.
The East Asian winter monsoon, which is associated with the Siberian high and active cold surges, is one of the most energetic monsoon circulation systems. The dramatic shift of northeasterlies and the outbreak of cold surges dominate the winter weather and local climate in the East Asian region, and may exert a strong impact on the extratropical and tropical planetary-scale circulations and influence the SSTs in the tropical western Pacific. General characteristics of the winter monsoon and cold surges and their possible link with tropical disturbances are revealed in many observational studies. Little attention has been given to the climatological aspects of the winter monsoon and cold surges. The purpose of this study is to compile and document the East Asian mean winter circulation, and present the climatology of cold surges and the Siberian high based on the 1979--1995 NCEP/NCAR reanalyses. Of particular interest is the interannual variation of winter monsoon circulation and cold surge events. Given that the cold surge activity and the Indonesian convection are much reduced during the 1982--83 period, one of the goals is to determine whether there exists a statistically significant relationship between ENSO and the interannual variation of winter monsoon and cold surges.
Tao, Wenjing; Zou, Ming; Wang, Xuzhen; Gan, Xiaoni; Mayden, Richard L.; He, Shunping
Despite their great diversity and biological importance, evolutionary relationships among the endemic clade of East Asian Cyprinidae remain ambiguous. Understanding the phylogenetic history of this group involves many challenges. For instance, ecomorphological convergence may confound morphology-based phylogenetic inferences, and previous molecular phylogenetic studies based on single genes have often yielded contradictory and poorly supported trees. We assembled a comprehensive data matrix of 100 nuclear gene segments (∼ 71132 base pairs) for representative species of the endemic East Asian cyprinid fauna and recovered a robust phylogeny from this genome-wide signal supported by multiple analytical methods, including maximum parsimony, maximum likelihood and Bayesian inference. Relaxed molecular clock analyses indicated species radiations of this clade concentrated at approximately 1.9–7.6 MYA. We provide evidence that the bursts of diversification in this fauna are directly linked to major paleoenvironmental events associated with monsoon evolution occurring from late Miocene to Pliocene. Ancestral state reconstruction reveals convergent morphological characters are hypothesized to be independent products of similar selective pressures in ecosystems. Our study is the first comprehensive phylogenetic study of the enigmatic East-Asian cyprinids. The explicit molecular phylogeny provides a valuable framework for future research in genome evolution, adaptation and speciation of cyprinids. PMID:20976012
Xiang, Yang; Yang, Xiuqun
Using ERA-40 reanalysis daily data for the period 1958-2002, this study investigated the effect of transient eddy (TE) on the interannual meridional displacement of summer East Asian subtropical jet (EASJ) by conducting a detailed dynamical diagnosis. The summer EASJ axis features a significant interannual coherent meridional displacement. Associated with such a meridional displacement, the TE vorticity forcing anomalies are characterized by a meridional dipole pattern asymmetric about the climatological EASJ axis. The TE vorticity forcing anomalies yield barotropic zonal wind tendencies with a phase meridionally leading the zonal wind anomalies, suggesting that they act to reinforce further meridional displacement of the EASJ and favor a positive feedback in the TE and time-mean flow interaction. However, The TE thermal forcing anomalies induce baroclinic zonal wind tendencies that reduce the vertical shear of zonal wind and atmospheric baroclinicity and eventually suppress the TE activity, favoring a negative feedback in the TE and time-mean flow interaction. Although the two types of TE forcing tend to have opposite feedback roles, the TE vorticity forcing appears to be dominant in the TE effect on the time-mean flow.
Li, Fei; Wang, Huijun
The interannual variability of East Asian winter monsoon (EAWM) circulation from the Development of a European Multi-Model Ensemble (MME) System for Seasonal to Inter-Annual Prediction (DEMETER) hindcasts was evaluated against observation reanalysis data. We evaluated the DEMETER coupled general circulation models (CGCMs)' retrospective prediction of the typical EAWM and its associated atmospheric circulation. Results show that the EAWM can be reasonably predicted with statistically significant accuracy, yet the major bias of the hindcast models is the underestimation of the related anomalies. The temporal correlation coefficient (TCC) of the MME-produced EAWM index, defined as the first EOF mode of 850-hPa air temperature within the EAWM domain (20°-60°N, 90°-150°E), was 0.595. This coefficient was higher than those of the corresponding individual models (range: 0.39-0.51) for the period 1969-2001; this result indicates the advantage of the super-ensemble approach. This study also showed that the ensemble models can reasonably reproduce the major modes and their interannual variabilities for sea level pressure, geopotential height, surface air temperature, and wind fields in Eurasia. Therefore, the prediction of EAWM interannual variability is feasible using multimodel ensemble systems and that they may also reveal the associated mechanisms of the EAWM interannual variability.
Oh, Hyoeun; Ha, Kyung-Ja
Intraseasonal monsoon prediction is the most imperative task, but there remains an enduring challenge in climate science. The present study aims to provide a physical understanding of the sources for prediction of dominant intraseasonal modes in the East Asian-western North Pacific summer monsoon (EA-WNPSM): pre-Meiyu&Baiu, Changma&Meiyu, WNPSM, and monsoon gyre modes classified by the self-organizing map analysis. Here, we use stepwise regression to determine the predictors for the four modes in the EA-WNPSM. The selected predictors are based on the persistent and tendency signals of the sea surface temperature (SST)/2m air temperature and sea level pressure fields, which reflect the asymmetric response to the El Niño Southern Oscillation (ENSO) and the ocean and land surface anomalous conditions. For the pre-Meiyu&Baiu mode, the SST cooling tendency over the western North Pacific (WNP), which persists into summer, is the distinguishing contributor that results in strong baroclinic instability. A major precursor for the Changma&Meiyu mode is related to the WNP subtropical high, induced by the persistent SST difference between the Indian Ocean and the western Pacific. The WNPSM mode is mostly affected by the Pacific-Japan pattern, and monsoon gyre mode is primarily associated with a persistent SST cooling over the tropical Indian Ocean by the preceding ENSO signal. This study carries important implications for prediction by establishing valuable precursors of the four modes including nonlinear characteristics.
Zhang, Leying; Xu, Haiming; Shi, Ning; Deng, Jiechun
This study concerns atmospheric responses to the North Pacific subtropical front (NPSTF) in boreal spring over the period 1982-2014. Statistical results show that a strong NPSTF in spring can significantly enhance the East Asian jet stream (EAJS). Both transient eddy activity and the atmospheric heat source play important roles in this process. The enhanced atmospheric temperature gradient due to a strong NPSTF increases atmospheric baroclinicity, resulting in an intensification of transient eddy and convection activities. On the one hand, the enhanced transient eddy activities can excite an anomalous cyclonic circulation with a quasi-baraotropical structure in the troposphere to the north of the NPSTF. Accordingly, the related westerly wind anomalies around 30°N can intensify the component of the EAJS over the Northeast Pacific. On the other hand, an enhanced atmospheric heat source over the NPSTF, which is related to increased rainfall, acts to excite an anomalous cyclonic circulation system in the troposphere to the northwest of the NPSTF, which can explain the enhanced component of the EAJS over the Northwest Pacific. The two mechanisms may combine to enhance the EAJS.
Zuo, Jinqing; Li, Weijing; Sun, Chenghu; Xu, Li; Ren, Hong-Li
A strong (weak) East Asian summer monsoon (EASM) is usually concurrent with the tripole pattern of North Atlantic SST anomalies on the interannual timescale during summer, which has positive (negative) SST anomalies in the northwestern North Atlantic and negative (positive) SST anomalies in the subpolar and tropical ocean. The mechanisms responsible for this linkage are diagnosed in the present study. It is shown that a barotropic wave-train pattern occurring over the Atlantic-Eurasia region likely acts as a link between the EASM and the SST tripole during summer. This wave-train pattern is concurrent with geopotential height anomalies over the Ural Mountains, which has a substantial effect on the EASM. Diagnosis based on observations and linear dynamical model results reveals that the mechanism for maintaining the wave-train pattern involves both the anomalous diabatic heating and synoptic eddy-vorticity forcing. Since the North Atlantic SST tripole is closely coupled with the North Atlantic Oscillation (NAO), the relationships between these two factors and the EASM are also examined. It is found that the connection of the EASM with the summer SST tripole is sensitive to the meridional location of the tripole, which is characterized by large seasonal variations due to the north-south movement of the activity centers of the NAO. The SST tripole that has a strong relationship with the EASM appears to be closely coupled with the NAO in the previous spring rather than in the simultaneous summer.
Zhang, Hongli; Zhang, Qiang; Yue, Ping; Zhang, Liang; Liu, Qian; Qiao, Shaobo; Yan, Pengcheng
In this study, the variability of the aridity over a semiarid zone in Northern China from 1961 to 2013 and its association with the northernmost margin of the East Asian summer monsoon (EASM) and its intensity were investigated using composite analysis, correlative analysis, and unrotated and rotated empirical orthogonal function analyses. The results indicate that a nonsignificant drying trend (0.03/10 years) occurs over the entire eastern semiarid zone, accompanied by a southward retreat in the northernmost margin of the EASM (0.24°/10 years), and that drying (0.11/10 years) and southward retreat (0.28°/10 years) are most obvious on the Loess Plateau. The response of the annual variation of aridity to changes in the northernmost margin of the EASM is also compared with its responses to changes in the intensity of the EASM; the results indicate that it is more related to the former, especially over the Loess Plateau. Furthermore, an abnormal aridity event is likely to occur over the Loess Plateau in a year when the EASM margin advances to its northernmost latitude abnormally ahead of time and retreats abnormally ahead of time compared to the mean state.
Goldsmith, Yonaton; Broecker, Wallace S; Xu, Hai; Polissar, Pratigya J; deMenocal, Peter B; Porat, Naomi; Lan, Jianghu; Cheng, Peng; Zhou, Weijian; An, Zhisheng
The magnitude, rate, and extent of past and future East Asian monsoon (EAM) rainfall fluctuations remain unresolved. Here, late Pleistocene-Holocene EAM rainfall intensity is reconstructed using a well-dated northeastern China closed-basin lake area record located at the modern northwestern fringe of the EAM. The EAM intensity and northern extent alternated rapidly between wet and dry periods on time scales of centuries. Lake levels were 60 m higher than present during the early and middle Holocene, requiring a twofold increase in annual rainfall, which, based on modern rainfall distribution, requires a ∼400 km northward expansion/migration of the EAM. The lake record is highly correlated with both northern and southern Chinese cave deposit isotope records, supporting rainfall "intensity based" interpretations of these deposits as opposed to an alternative "water vapor sourcing" interpretation. These results indicate that EAM intensity and the northward extent covary on orbital and millennial timescales. The termination of wet conditions at 5.5 ka BP (∼35 m lake drop) triggered a large cultural collapse of Early Neolithic cultures in north China, and possibly promoted the emergence of complex societies of the Late Neolithic.
Al-koshab, May; Nambiar, Phrabhakaran; John, Jacob
Introduction Proper imaging allows practitioners to evaluate an asymptomatic tempormandibular joint (TMJ) for potential degenerative changes prior to surgical and orthodontic treatment. The recently developed cone-beam computed tomography (CBCT) allows measurement of TMJ bony structures with high accuracy. A study was undertaken to determine the morphology, and its variations, of the mandibular condyle and glenoid fossa among Malay and Chinese Malaysians. Methods CBCT was used to assess 200 joints in 100 subjects (mean age, 30.5 years). i-CAT CBCT software and The Mimics 16.0 software were employed to measure the volume, metrical size, position of each condyle sample and the thickness of the roof of the glenoid fossa (RGF). Results No significant gender differences were noted in thickness of the RGF and condylar length; however condylar volume, width, height and the joint spaces were significantly greater among males. With regards to comparison of both TMJs, the means of condylar volume, width and length of the right TMJ were significantly higher, while the means of the left condylar height and thickness of RGF were higher. When comparing the condylar measurements and the thickness of RGF between the two ethnic groups, we found no significant difference for all measurements with exception of condylar height, which is higher among Chinese. Conclusion The similarity in measurements for Malays and Chinese may be due to their common origin. This information can be clinically useful in establishing the diagnostic criteria for condylar volume, metrical size, and position in the Malaysian East Asians population. PMID:25803868
Wang, Xueyuan; Liang, Xin-Zhong; Jiang, Weimei; Tao, Zhining; Wang, Julian X. L.; Liu, Hongnian; Han, Zhiwei; Liu, Shuyan; Zhang, Yuyan; Grell, Georg A.; Peckham, Steven E.
This study develops fine temporal (seasonal, day-of-week, diurnal) and vertical allocations of anthropogenic emissions for the TRACE-P inventory and evaluates their impacts on the East Asian air quality prediction using WRF-Chem simulations in July 2001 at 30-km grid spacing against available surface measurements from EANET and NEMCC. For NO 2 and SO 2, the diurnal and vertical redistributions of emissions play essential roles, while the day-of-week variation is less important. When all incorporated, WRF-Chem best simulates observations of surface NO 2 and SO 2 concentrations, while using the default emissions produces the worst result. The sensitivity is especially large over major cities and industrial areas, where surface NO 2 and SO 2 concentrations are reduced by respectively 3-7 and 6-12 ppbv when using the scaled emissions. The incorporation of all the three redistributions of emissions simulates surface O 3 concentrations higher by 4-8 ppbv at night and 2-4 ppbv in daytime over broad areas of northern, eastern and central China. To this sensitivity, the diurnal redistribution contributes more than the other two.
Son, J. H.; Seo, K. H.
This work provides a new perspective on the major factors controlling the East Asian summer monsoon (EASM) in July, and a promising physical-statistical forecasting of the EASM ahead of summer. Dominant modes of the EASM are revealed from the variability of large-scale air masses discerned by equivalent potential temperature, and are found to be dynamically connected with the anomalous sea surface temperatures (SSTs) over the three major oceans of the world and their counterparts of prevailing atmospheric oscillation or teleconnection patterns. Precipitation over Northeast Asia (NEA) during July is enhanced by the tropical central Indian Ocean warming and central Pacific El Niño-related SST warming, the northwestern Pacific cooling off the coast of NEA, and the North Atlantic Ocean warming. Using these factors and data from the preceding spring seasons, the authors build a multiple linear regression model for seasonal forecasting. The cross-validated correlation skill predicted for the period 1994 to 2012 is up to 0.84, which far exceeds the skill level of contemporary climate models.
Chen, J.; Bordoni, S.
The regional climate change of the East Asian summer monsoon is investigated in the Coupled Model Inter-comparison Project - Phase 5 (CMIP5) archive in the context of the moist static energy budget. In the greenhouse gas forcing scenario, the reduction of radiative cooling and the increase of continental surface temperature occur much more rapidly than changes in sea surface temperatures (SSTs). Without changes in SSTs, the rainfall in the oceanic monsoon region decreases, despite an increase in the land-sea thermal contrast traditionally considered as a fundamental driver of monsoons. The reduction in precipitation is robust amongst all CMIP5 models and is primarily attributable to a weakening of the subtropical westerly jet. The weakening of the jet, in turn, can be explained by changes in upper-level eddy momentum flux convergence and thermal wind balance. On longer time scales, SSTs increase, as does monsoon rainfall. This delayed precipitation increase is primarily driven by the thermodynamic contribution to precipitation changes, by which wet regions get wetter and dry regions get drier. Dynamical changes due to changes in circulation play a secondary effect. These results clearly highlight deficits of commonly proposed geo-engineering schemes as climate mitigation strategies, which, by reducing the surface warming without sequestration of CO2, might still result in dramatic changes in rainfall, especially in heavily populated monsoonal regions. Similar analyses will be applied to other subtropical convergence zones in the Earth's atmosphere.
Huang, Bo; Kadow, Christopher; Cubasch, Ulrich
The East Asian summer monsoon (EASM) is a strong monsoon system with a complicated internal variation. Its seasonal predictability is a long-standing issue in climate science. We analysed the seasonal prediction skill of EASM and the correlation between EASM and El Niño Southern Oscillation (ENSO). Our study is based on historical and decadal experiments of six prediction systems (i.e., BCC-CMS1.1, CanCM4, GFDL-CM2p1, HadCM3, MIROC5 and MPI-ESM-LR) from the Coupled Model Intercomparison Project phase 5 (CMIP5) in 1979-2005. We find that initialised simulations improve the prediction skill of EASM in CanCM4 and GFDL-CM2p1 model experiments, but lower it in the HadCM3 simulation, especially after the anomaly initialisation. The better predictability of EASM in the CanCM4 and GFDL-CM2p1 simulations due to their good performance in capturing the coupled ENSO-EASM mode, which is better than in the HadCM3 experiments. In predicting EASM, the coupled Southern Oscillation-EASM mode plays a more important role than the coupled El Niño-EASM mode.
Khaja, Amjad Hussain; Zwiad, Abdulsalam Ali; Tarakji, Bassel; Gazal, Giath; Albaba, Feras; KalajI, Nader; Petro, Waleed
Background & Objective: The purpose of the study was to understand the dependency on smokeless tobacco. Methods: The major aspect of the interview was to study the type of chewing tobacco used, frequency of purchase of chewing tobacco, change in attitude and behavior after the use of chewing tobacco. This study was done in 2005 in London. Of the 110 respondents interviewed 88 were used for the data analysis. Study Design: An exploratory study was conducted in East London, United Kingdom. The selected sample was interviewed through a questionnaire, based on the Severson Smokeless Tobacco Dependence Scale. Results: Cross tabulations report that in a sample of 88 South Asian UK resident men 46.6% used leaf (paan), 43.2% used processed form of chewing tobacco and 10.2% used gutka. Older age (67%) respondents were more likely than the younger age (30%) respondents to chew tobacco. The frequency of purchase of chewing tobacco is reported high (67.2%) in the older age group than the younger age group (50%). Conclusion: This current study used an amended form of the Severson Smokeless Tobacco Scale questionnaire to study the dependency on smokeless tobacco. The study could be developed in the selection of the sample, which would include both males and females to study the dependency on smokeless tobacco. PMID:26234985
Chen, Xiong; Li, Chongyin; Ling, Jian; Tan, Yanke
This paper investigates the processes and mechanisms by which the East Asian winter monsoon (EAWM) affects the Madden-Julian oscillation (MJO) over the equatorial western Pacific in boreal winter (November-April). The results show that both the EAWM and MJO over the equatorial western Pacific have prominent interannual and interdecadal variabilities, and they are closely related, especially on the interannual timescales. The EAWM influences MJO via the feedback effect of convective heating, because the strong northerlies of EAWM can enhance the ascending motion and lead the convection to be strengthened over the equatorial western Pacific by reinforcing the convergence in the lower troposphere. Daily composite analysis in the phase 4 of MJO (i.e., strong MJO convection over the Maritime Continent and equatorial western Pacific) shows that the kinetic energy, outgoing longwave radiation (OLR), moisture flux, vertical velocity, zonal wind, moist static energy, and atmospheric stability differ greatly between strong and weak EAWM processes over the western Pacific. The strong EAWM causes the intensity of MJO to increase, and the eastward propagation of MJO to become more persistent. MJO activities over the equatorial western Pacific have different modes. Furthermore, these modes have differing relationships with the EAWM, and other factors can also affect the activities of MJO; consequently, the relationship between the MJO and EAWM shows both interannual and interdecadal variabilities.
Liu, Hongyan; Yin, Yi; Hao, Qian; Liu, Guo
Estimating vegetation sensitivity during the Holocene will improve the predictions of future vegetation dynamics. We compiled 52 pollen sequences from the monsoon-influenced northern China to reconstruct the Holocene dynamics of three forest types dominated respectively by Pinus, Quercus and Betula, as well as steppe and desert indicated respectively by Artemisia and Chenopodiaceae. The sensitivities of these vegetation types to changes in intensity of the East Asian monsoon were calculated according to the elevation, temperature and precipitation groupings of sites. Our results show that the Holocene vegetation dynamics differed across vegetation types, with Pinus and Quercus at lower elevations more sensitive to monsoon-induced precipitation changes and Betula at higher elevations more sensitive to temperature changes at the beginning of the Holocene. We also found an increasing sensitivity for forests and steppe within different groups following evident reduction in monsoon intensity since 5 ka BP, caused most probably by climate drying in this drought-determined forest-steppe in northern China. Besides regional scale forest retreat caused by climate drying, elevational movement as well as site expansion and decline are also suggested to explain low vegetation sensitivities in some site-groups. Our study provides insights into the mechanisms of individualistic responses of plant taxa as well as the asymmetrical response of ecotonal vegetation to the Holocene monsoon development in China.
Bing, Jian; Han, Pei-Jie; Liu, Wan-Qiu; Wang, Qi-Ming; Bai, Feng-Yan
Lager-brewing arose in 15th century Bavaria  and is nowadays the most popular technique for alcoholic beverage production in the world. The technique is characterized by low temperature fermentation using the domesticated yeast Saccharomyces pastorianus (synonym S. carlsbergensis). It has been clear that the lager yeast is a hybrid with one portion of its genome having originated from S. cerevisiae ale yeast . However, the source of the non-ale subgenome, which endows lager yeast with cold tolerance, had been a matter of debate . Recently, a Patagonian origin hypothesis of lager yeast has been proposed based on the discovery of a new cryotolerant Saccharomyces species from Patagonian native forests of Argentina . This yeast, named S. eubayanus, exhibited the closest known match (99.56%) to the non-ale portion of lager yeast and, thus, was believed to be its progenitor. However, we now show that this yeast species is likely native to the Tibetan Plateau. One of the Tibetan populations of the species exhibits closer affinity with lager yeast than the Patagonian population as inferred from population genetics and genome sequence analyses. We thus provide strong evidence for a Far East Asian origin hypothesis of lager yeast, which apparently corresponds better with geography and world trade history.
Ding, Hui; Greatbatch, Richard; Lu, Jian
The variability of the East Asian summer monsoon (EASM) is studied using a pacemaker technique in a atmospheric general circulation model (AGCM) coupled to a slab mixed layer model. In the pacemaker experiment, sea surface temperature (sst) is constrained to observations in the eastern equatorial Pacific throughout a q-flux that measures the contribution of ocean dynamics to SST variability, while the AGCM is still coupled to the slab model. An ensemble of pacemaker experiments is analysed using a multivariate EOF analysis to identify the two major modes of variability of the EASM. Results show that the pacemaker experiments simulate part of the variability of the first mode seen in the ERA40 reanalysis (correlation up to 0.67 for the model ensemble mean), as expected. Different from previous study, the pacemaker experiments also simulate part of the variabilty (correlation up to 0.51 for the model ensemble mean) of the second mode, a mode of variability that is related to that of the Indian Summer Monsoon. A possible reason is the success of the pacemaker experiments at reproducing the relationship between El Nino Southern Oscillation (ENSO) and the second mode of EASM.
Ding, Hui; Greatbatch, Richard J.; Lu, Jian; Cash, Ben
The variability of the East Asian summer monsoon (EASM) is studied using a pacemaker technique driven by ENSO in an atmospheric general circulation model (AGCM) coupled to a slab mixed layer model. In the pacemaker experiments, sea surface temperature (SST) is constrained to observations in the eastern equatorial Pacific through a q- flux that measures the contribution of ocean dynamics to SST variability, while the AGCM is coupled to the slab model. An ensemble of pacemaker experiments is analyzed using a multivariate EOF analysis to identify the two major modes of variability of the EASM. The results show that the pacemaker experiments simulate a substantial amount (around 45 %) of the variability of the first mode (the Pacific-Japan pattern) in ERA40 from 1979 to 1999. Different from previous work, the pacemaker experiments also simulate a large part (25 %) of the variability of the second mode, related to rainfall variability over northern China. Furthermore, we find that the lower (850 hPa) and the upper (200 hPa) tropospheric circulation of the first mode display the same degree of reproducibility whereas only the lower part of the second mode is reproducible. The basis for the success of the pacemaker experiments is the ability of the experiments to reproduce the observed relationship between El Niño Southern Oscillation (ENSO) and the EASM.
Jang, Haeyoung; Koo, Fung Kuen; Ke, Liang; Clemson, Lindy; Cant, Rosemary; Fraser, David R; Seibel, Marcus J; Tseng, Marilyn; Mpofu, Elias; Mason, Rebecca S; Brock, Kaye
In this qualitative study, researchers examined cultural and attitudinal factors that might be related to sun-exposure behaviors among East Asian women living in Australia. Researchers asked Chinese (n = 20) and Korean (n = 16) immigrant women who participated in a larger cross-sectional quantitative study of vitamin D blood levels to volunteer to participate in an in-depth interview in 2010. These women reported a number of cultural factors related to their attitudes and behaviors with regard to sun exposure. They expressed preference for fair skin, a tradition of covering skin when outdoors, and no sunbathing culture. They believed that fair skin was more beautiful than tanned skin. They reported that beauty was the reason for active avoidance of sunlight exposure. Although they reported knowledge of the need for sun avoidance due to skin cancer risk, few reported knowledge about the benefits of sun exposure for adequate vitamin D levels. These findings may provide some reasons for vitamin D deficiency previously reported in these populations. Thus, researchers recommend that these attitudes of excessive sun protection and limiting sun exposure be further investigated as they may have implications for planning and delivery of health promotion programs to this growing population of immigrants in Australia.
Yoon, Eunju; Adams, Kristen; Clawson, Angela; Chang, Hanna; Surya, Shruti; Jérémie-Brink, Gihane
Drawing on the current conceptualization of acculturation/enculturation as bilinear, multidimensional processes proceeding in interaction with surrounding contexts, this study examined ethnic identity development and cultural integration of 13 adolescents from East Asian immigrant families. Five domains emerged via the Consensual Qualitative Research method: ethnic/cultural identity and socialization; bicultural living; racial context-racism and stereotypes; family context-parental expectation; and peer context-friendship/dating. Overall, the participants experienced a cultural split and discontinuity between the 2 worlds of home and ethnic community versus school and society in general. They received strong ethnic socialization messages from family and ethnic community. Although most participants experienced hurtful racial discrimination, they used passive coping (e.g., dismiss, minimize, defend perpetrators). The model minority stereotype was prevalent and deeply engrained in many aspects of their lives including ethnic identity development, cultural socialization messages from mainstream society, discrimination experiences, and academic/occupational demands imposed by self, parents, peers, and society. Although they appreciated parents' high expectations of academic/occupational success, they felt pressured and desired to have space and independence. Friendship/dating patterns reflected ethnic identity development as well as contextual influence. Implications for research and practice are discussed. (PsycINFO Database Record
Background Currently, there is very limited knowledge about the genes involved in normal pigmentation variation in East Asian populations. We carried out a genome-wide scan of signatures of positive selection using the 1000 Genomes Phase I dataset, in order to identify pigmentation genes showing putative signatures of selective sweeps in East Asia. We applied a broad range of methods to detect signatures of selection including: 1) Tests designed to identify deviations of the Site Frequency Spectrum (SFS) from neutral expectations (Tajima’s D, Fay and Wu’s H and Fu and Li’s D* and F*), 2) Tests focused on the identification of high-frequency haplotypes with extended linkage disequilibrium (iHS and Rsb) and 3) Tests based on genetic differentiation between populations (LSBL). Based on the results obtained from a genome wide analysis of 25 kb windows, we constructed an empirical distribution for each statistic across all windows, and identified pigmentation genes that are outliers in the distribution. Results Our tests identified twenty genes that are relevant for pigmentation biology. Of these, eight genes (ATRN, EDAR, KLHL7, MITF, OCA2, TH, TMEM33 and TRPM1,) were extreme outliers (top 0.1% of the empirical distribution) for at least one statistic, and twelve genes (ADAM17, BNC2, CTSD, DCT, EGFR, LYST, MC1R, MLPH, OPRM1, PDIA6, PMEL (SILV) and TYRP1) were in the top 1% of the empirical distribution for at least one statistic. Additionally, eight of these genes (BNC2, EGFR, LYST, MC1R, OCA2, OPRM1, PMEL (SILV) and TYRP1) have been associated with pigmentary traits in association studies. Conclusions We identified a number of putative pigmentation genes showing extremely unusual patterns of genetic variation in East Asia. Most of these genes are outliers for different tests and/or different populations, and have already been described in previous scans for positive selection, providing strong support to the hypothesis that recent selective sweeps left a
Spracklen, Cassandra N; Chen, Peng; Kim, Young Jin; Wang, Xu; Cai, Hui; Li, Shengxu; Long, Jirong; Wu, Ying; Wang, Ya Xing; Takeuchi, Fumihiko; Wu, Jer-Yuarn; Jung, Keum-Ji; Hu, Cheng; Akiyama, Koichi; Zhang, Yonghong; Moon, Sanghoon; Johnson, Todd A; Li, Huaixing; Dorajoo, Rajkumar; He, Meian; Cannon, Maren E; Roman, Tamara S; Salfati, Elias; Lin, Keng-Hung; Guo, Xiuqing; Sheu, Wayne H H; Absher, Devin; Adair, Linda S; Assimes, Themistocles L; Aung, Tin; Cai, Qiuyin; Chang, Li-Ching; Chen, Chien-Hsiun; Chien, Li-Hsin; Chuang, Lee-Ming; Chuang, Shu-Chun; Du, Shufa; Fan, Qiao; Fann, Cathy S J; Feranil, Alan B; Friedlander, Yechiel; Gordon-Larsen, Penny; Gu, Dongfeng; Gui, Lixuan; Guo, Zhirong; Heng, Chew-Kiat; Hixson, James; Hou, Xuhong; Hsiung, Chao Agnes; Hu, Yao; Hwang, Mi Yeong; Hwu, Chii-Min; Isono, Masato; Juang, Jyh-Ming Jimmy; Khor, Chiea-Chuen; Kim, Yun Kyoung; Koh, Woon-Puay; Kubo, Michiaki; Lee, I-Te; Lee, Sun-Ju; Lee, Wen-Jane; Liang, Kae-Woei; Lim, Blanche; Lim, Sing-Hui; Liu, Jianjun; Nabika, Toru; Pan, Wen-Harn; Peng, Hao; Quertermous, Thomas; Sabanayagam, Charumathi; Sandow, Kevin; Shi, Jinxiu; Sun, Liang; Tan, Pok Chien; Tan, Shu-Pei; Taylor, Kent D; Teo, Yik-Ying; Toh, Sue-Anne; Tsunoda, Tatsuhiko; van Dam, Rob M; Wang, Aili; Wang, Feijie; Wang, Jie; Wei, Wen Bin; Xiang, Yong-Bing; Yao, Jie; Yuan, Jian-Min; Zhang, Rong; Zhao, Wanting; Chen, Yii-Der Ida; Rich, Stephen S; Rotter, Jerome I; Wang, Tzung-Dau; Wu, Tangchun; Lin, Xu; Han, Bok-Ghee; Tanaka, Toshihiro; Cho, Yoon Shin; Katsuya, Tomohiro; Jia, Weiping; Jee, Sun-Ha; Chen, Yuan-Tsong; Kato, Norihiro; Jonas, Jost B; Cheng, Ching-Yu; Shu, Xiao-Ou; He, Jiang; Zheng, Wei; Wong, Tien-Yin; Huang, Wei; Kim, Bong-Jo; Tai, E-Shyong; Mohlke, Karen L; Sim, Xueling
Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). With differences in linkage disequilibrium (LD) structure and allele frequencies between ancestry groups, studies in additional large samples may detect new associations. We conducted staged GWAS meta-analyses in up to 69,414 East Asian individuals from 24 studies with participants from Japan, the Philippines, Korea, China, Singapore, and Taiwan. These meta-analyses identified (P < 5 × 10-8) three novel loci associated with HDL-C near CD163-APOBEC1 (P = 7.4 × 10-9), NCOA2 (P = 1.6 × 10-8), and NID2-PTGDR (P = 4.2 × 10-8), and one novel locus associated with TG near WDR11-FGFR2 (P = 2.7 × 10-10). Conditional analyses identified a second signal near CD163-APOBEC1. We then combined results from the East Asian meta-analysis with association results from up to 187,365 European individuals from the Global Lipids Genetics Consortium in a trans-ancestry meta-analysis. This analysis identified (log10Bayes Factor ≥6.1) eight additional novel lipid loci. Among the twelve total loci identified, the index variants at eight loci have demonstrated at least nominal significance with other metabolic traits in prior studies, and two loci exhibited coincident eQTLs (P < 1 × 10-5) in subcutaneous adipose tissue for BPTF and PDGFC. Taken together, these analyses identified multiple novel lipid loci, providing new potential therapeutic targets.
Li, Xinxin; Wu, Zhiwei; Li, Yanjie
Arctic sea ice (ASI) and its potential climatic impacts have received increasing attention during the past decades, yet the relevant mechanisms are far from being understood, particularly on how anomalous ASI affects climate in midlatitudes. The spring precipitation takes up as much as 30% of the annual total and has significant influences to agriculture in East Asia. Here, observed evidence and numerical experiment results manifest that the ASI variability in the Norwegian Sea and the Barents Sea in preceding winter is intimately connected with interannual variations of the East Asian spring precipitation (EAP). The former can explain about 14% of the total variances of the latter. The ASI anomalies persist from winter through the ensuing spring and excite downstream tele-connections of a distinct Rossby wave train prevailing over the Eurasian continent. For the reduced ASI, such a wave train pattern is usually associated with an anomalous low pressure center over Mongolian Plateau, which accelerates the East Asian subtropical westerly jet. The intensified subtropical westerly jet, concurrent with lower-level convergence and upper-level divergence, enhances the local convection and consequently favors rich spring precipitation over East Asia. For the excessive ASI, the situation tends to be opposite. Given that seasonal prediction of the EAP remains a challenging issue, the winter ASI variability may provide another potential predictability source besides El Niño-Southern Oscillation.
Li, Chaofan; Lin, Zhongda
The interannual variation of the East Asian upper-tropospheric westerly jet (EAJ) significantly affects East Asian climate in summer. Identifying its performance in model prediction may provide us another viewpoint, from the perspective of upper-tropospheric circulation, to understand the predictability of summer climate anomalies in East Asia. This study presents a comprehensive assessment of year-to-year variability of the EAJ based on retrospective seasonal forecasts, initiated from 1 May, in the five state-of-the-art coupled models from ENSEMBLES during 1960-2005. It is found that the coupled models show certain capability in describing the interannual meridional displacement of the EAJ, which reflects the models' performance in the first leading empirical orthogonal function (EOF) mode. This capability is mainly shown over the region south of the EAJ axis. Additionally, the models generally capture well the main features of atmospheric circulation and SST anomalies related to the interannual meridional displacement of the EAJ. Further analysis suggests that the predicted warm SST anomalies in the concurrent summer over the tropical eastern Pacific and northern Indian Ocean are the two main sources of the potential prediction skill of the southward shift of the EAJ. In contrast, the models are powerless in describing the variation over the region north of the EAJ axis, associated with the meridional displacement, and interannual intensity change of the EAJ, the second leading EOF mode, meaning it still remains a challenge to better predict the EAJ and, subsequently, summer climate in East Asia, using current coupled models.
Wen, Xinyu; Liu, Zhengyu; Wang, Shaowu; Cheng, Jun; Zhu, Jiang
Understanding the past significant changes of the East Asia Summer Monsoon (EASM) and Winter Monsoon (EAWM) is critical for improving the projections of future climate over East Asia. One key issue that has remained outstanding from the paleo-climatic records is whether the evolution of the EASM and EAWM are correlated. Here, using a set of long-term transient simulations of the climate evolution of the last 21,000 years, we show that the EASM and EAWM are positively correlated on the orbital timescale in response to the precessional forcing, but are anti-correlated on millennial timescales in response to North Atlantic melt water forcing. The relation between EASM and EAWM can differ dramatically for different timescales because of the different response mechanisms, highlighting the complex dynamics of the East Asian monsoon system and the challenges for future projection. PMID:27328616
Ng, Edwin; Muntaner, Carles; Chung, Haejoo
Recent scholarship offers different theories on how macrosocial determinants affect the population health of East and Southeast Asian nations. Dominant theories emphasize the effects of welfare regimes, welfare generosity, and labor market institutions. In this article, we conduct exploratory time-series cross-sectional analyses to generate new evidence on these theories while advancing a political explanation. Using unbalanced data of 7 East Asian countries and 11 Southeast Asian nations from 1960 to 2012, primary findings are 3-fold. First, welfare generosity measured as education and health spending has a positive impact on life expectancy, net of GDP. Second, life expectancy varies significantly by labor markets; however, these differences are explained by differences in welfare generosity. Third, as East and Southeast Asian countries become more democratic, welfare generosity increases, and population health improves. This study provides new evidence on the value of considering politics, welfare states, and labor markets within the same conceptual framework.
Sperber, K.R.; Potter, G.L.; Boyle, J.S.; Hameed, S.
The ability of the ECMWF model (Cycle 33) to simulate the Indian and East Asian summer monsoon is evaluated at four different horizontal resolutions: T21, T42, T63, and T106. Generally, with respect to the large scale features of the circulation, the largest differences among the simulations occur at T42 relative to T21. However, on regional scales, important differences among the high frequency temporal variabilitY serve as a further critical test of the model`s ability to simulate the monsoon. More generally, the results indicate the importance of evaluating high frequency time scales as a component of the climate system. T106 best captures both the spatial and temporal characteristics of the Indian and East Asian Monsoon, while T42 fails to correctly simulate the sequence and development of synoptic scale milestones that characterize the monsoon flow. In particular, T106 is superior at simulating the development and migration of the monsoon trough over the Bay of Bengal. In the T42 simulation, the development of the monsoon occurs one month earlier than typically observed. At this time the trough is incorrectly located adjacent to the east coast of India which results in an underestimate of precipitation over the Burma/Thailand region. This early establishment of the monsoon trough affects the evolution of the East-Asian monsoon and yields excessive preseason rainfall over the Mei-yu region. EOF analysis of precipitation over China indicates that T106 best simulates the Mei-yu mode of variability associated with an oscillation of the rainband that gives rise to periods of enhanced rainfall over the Yangize River Valley. The coarse resolution of T21 precludes simulation of the aforementioned regional scale monsoon flows.
Liu, J.; Mauzerall, D. L.; Horowitz, L. W.
We analyze the effect of varying East Asian (EA) sulfur emissions on sulfate concentrations in the Northern Hemisphere, using a global coupled oxidant-aerosol model (MOZART-2). We conduct a base and five sensitivity simulations, in which sulfur emissions from each continent are tagged, to establish the source-receptor (S-R) relationship between EA sulfur emissions and sulfate concentrations over source and downwind regions. We find that from west to east across the North Pacific, EA sulfate contributes approximately 80% 20% of sulfate at the surface, but at least 50% at 500 hPa. Surface sulfate concentrations are dominated by local anthropogenic sources. Of the sulfate produced from sources other than local anthropogenic emissions (defined here as "background" sulfate), EA sources account for approximately 30% 50% (over the Western US) and 10% 20% (over the Eastern US). The surface concentrations of sulfate from EA sources over the Western US are highest in MAM (up to 0.15 μg/m3), and lowest in DJF (less than 0.06 μg/m3). Reducing EA SO2 emissions will significantly decrease the spatial extent of the EA sulfate influence (represented by the areas where at least 0.1 μg m-3 of sulfate originates from EA) over the North Pacific both at the surface and at 500 hPa in all seasons, but the extent of influence is insensitive to emission increases, particularly in DJF and JJA. We find that EA sulfate concentrations over most downwind regions respond nearly linearly to changes in EA SO2 emissions, but sulfate concentrations over the EA source region increase more slowly than SO2 emissions, particularly at the surface and in winter, due to limited availability of oxidants (in particular of H2O2, which oxidizes SO2 to sulfate in the aqueous phase). We find that similar estimates of the S-R relationship for trans-Pacific transport of EA sulfate would be obtained using either sensitivity (i.e., varying emissions from a region to examine the effects on downwind concentrations
Wu, Zhiwei; Yu, Lulu
Seasonal prediction of the East Asian summer monsoon (EASM) strength is probably one of the most challenging and crucial issues for climate prediction over East Asia. In this paper, a statistical method called partial-least square (PLS) regression is utilized to uncover principal sea surface temperature (SST) modes in the winter preceding the EASM. Results show that the SST pattern of the first PLS mode is associated with the turnabout of warming (or cooling) phase of a mega-El Niño/Southern Oscillation (mega-ENSO) (a leading mode of interannual-to-interdecadal variations of global SST), whereas that of the second PLS mode leads the warming/cooling mega-ENSO by about 1 year, signaling precursory conditions for mega-ENSO. These indicate that mega-ENSO may provide a critical predictability source for the EASM strength. Based on a 40-year training period (1958-1997), a PLS prediction model is constructed using the two leading PLS modes and 3-month-lead hindcasts are performed for the validation period of 1998-2013. A promising skill is obtained, which is comparable to the ensemble mean of versions 3 and 4 of the Canadian Community Atmosphere Model (CanCM3/4) hindcasts from the newly developed North American Multi-model Ensemble Prediction System regarding the interannual variations of the EASM strength. How to improve dynamical model simulation of the EASM is also examined through comparing the CanCM3/4 hindcast (1982-2010) with the 106-year historical run (1900-2005) by the Second Generation Canadian Earth System Model (CanESM2). CanCM3/4 exhibits a high skill in the EASM hindcast period 1982-2010 during which it also has a better performance in capturing the relationship between the EASM and mega-ENSO. By contrast, the simulation skill of CanESM2 is quite low and it is unable to reproduce the linkage between the EASM and mega-ENSO. All these results emphasize importance of mega-ENSO in seasonal prediction and dynamical model simulation of the EASM.
Sun, Li; Shen, Baizhu; Sui, Bo; Huang, Bohua
A unique dataset of 53-year (1961-2013) rainfall measurements from 104 stations uniformly distributed in the Northeast China, combined with the observation-based NCEP/NCAR atmospheric reanalysis, is used to analyze the precipitation anomalies in Northeast China during late boreal summer (July-August) and their relationship with the anomalous moisture transport associated with the fluctuations of the East Asian Summer Monsoon (EASM) circulation. Based on this analysis, a new EASM influence index ( I EASM ) is proposed to quantify the EASM effects on the Northeast China summer precipitation. The relationship between the IEASM variations and patterns of the anomalous regional atmospheric circulation is demonstrated. The characteristics of several precursors that lead to the major fluctuations of the I EASM index are also explored. The results show that the EASM influence index is closely linked to the anomalous rainfall in Northeast China and can be used as a major factor to measure the physical processes that affect the regional dry and wet conditions. The I EASM index responds to the large-scale anomalies of the atmospheric circulation sensitively. Specifically, the high I EASM values are associated with the intensified Mongolia cyclone, blocking developing near the Ural Mountains and a northwestward shift of subtropical high over the western Pacific. The low I EASM values are associated with a reversed pattern of these features. The I EASM anomalous fluctuation has some precursors. A major high (low) index during the summer is likely preceded with the pattern of the sea surface temperature anomalies of an El Niño (La Niña) event in the Pacific from the previous early fall to early winter.
Liu, J.; Mauzerall, D. L.; Horowitz, L. W.
We analyze the effect of varying East Asian (EA) sulfur emissions on sulfate concentrations in the northern hemisphere based on a global coupled oxidant-aerosol model (MOZART-2) driven with NCEP reanalysis meteorology for 1991. We conduct a base and several sensitivity simulations, in which sulfur emissions from each continent are tagged, to establish the source-receptor (S-R) relationship between EA sulfur emissions and sulfate concentrations over the source and downwind regions. We find that reducing EA SO2 emissions will significantly decrease the spatial extent of the EA sulfate influence over the North Pacific, but raising EA SO2 emissions will not significantly increase the spatial extent of influence. We define a linearity index and find the S-R relationship between EA SO2 emissions and EA sulfate concentrations to be nearly linear over most downwind regions, but to be non-linear over the EA source region, particularly at the surface and in winter. In addition, we find that besides the direct transport of EA sulfate to North America (NA) and Europe (EU), the indirect response of locally-produced NA or EU sulfate to changes in EA SO2 emissions is negative (i.e., offsetting the direct effect) in winter, spring and fall, but becomes positive in summer. In summer the indirect response is as important as direct transport of EA sulfate over the southeastern U.S. and southern EU. This summertime positive indirect effect largely results from induced changes in H2O2 oxidant concentrations over these regions.
MacDonald, S. M.; Oetjen, H.; Mahajan, A. S.; Whalley, L. K.; Edwards, P. M.; Heard, D. E.; Jones, C. E.; Plane, J. M. C.
Tropical rainforests act as a huge contributor to the global emissions of biogenic volatile organic compounds (BVOCs). Measurements of their oxidation products, such as formaldehyde (HCHO) and glyoxal (CHOCHO), provide useful indicators of fast photochemistry occurring in the lower troposphere. However, measurements of these species in tropical forest locations are extremely limited. To redress this, HCHO and CHOCHO were measured using the long-path (LP) and multi-axis (MAX) differential optical absorption spectroscopy (DOAS) techniques above the rainforest canopy in Borneo during two campaigns in spring and summer 2008, as part of the Oxidant and Particle Photochemical Processes above a South-East Asian tropical rainforest (OP3) project. The results were compared with concurrent measurements of hydroxyl radical (OH), isoprene (C5H8) (which was the dominant organic species emitted in this forest environment), and various meteorological parameters. Formaldehyde was observed at a maximum concentration of 4.5 ppb and glyoxal at a maximum of 1.6 ppb, significantly higher than previous measurements in rural locations. A 1-D chemistry model was then used to assess the diurnal evolution of formaldehyde and glyoxal throughout the boundary layer. The results, which compare well with the LP-DOAS and MAX-DOAS observations, suggest that the majority of the glyoxal and formaldehyde is confined to the first 500 m of the boundary layer, and that the measured ratio of these species is reproduced using currently accepted product yields for the oxidation of isoprene by OH. An important conclusion is that the measured levels of glyoxal are consistent with the surprisingly high concentrations of OH measured in this environment.
MacDonald, S. M.; Oetjen, H.; Mahajan, A. S.; Whalley, L. K.; Edwards, P. M.; Heard, D. E.; Jones, C. E.; Plane, J. M. C.
Tropical rainforests act as a huge contributor to the global emissions of biogenic volatile organic compounds (BVOCs). Measurements of their oxidation products, such as formaldehyde (HCHO) and glyoxal (CHOCHO), provide useful indicators of fast photochemistry occurring in the lower troposphere. However, measurements of these species in tropical forest locations are extremely limited. To redress this, HCHO and CHOCHO were measured using the long-path (LP) and multi-axis (MAX) differential optical absorption spectroscopy (DOAS) techniques above the rainforest canopy in Borneo during two campaigns in spring and summer 2008, as part of the Oxidant and Particle Photochemical Processes above a south-east Asian tropical rainforest (OP3) project. The results were compared with concurrent measurements of hydroxyl radical (OH), isoprene (C5H8) (which was the dominant organic species emitted in this forest environment), and various meteorological parameters. Formaldehyde was observed at a maximum concentration of 4.5 ppb and glyoxal at a maximum of 1.6 ppb, significantly higher than previous measurements in rural locations. A 1-D chemistry model was then used to assess the diurnal evolution of formaldehyde and glyoxal throughout the boundary layer. The results, which compare well with the LP-DOAS and MAX-DOAS observations, suggest that the majority of the glyoxal and formaldehyde is confined to the first 500 m of the boundary layer, and that the measured ratio of these species is reproduced using currently accepted product yields for the oxidation of isoprene by OH. An important conclusion is that the measured levels of glyoxal are consistent with the surprisingly high concentrations of OH measured in this environment.
Li, Jianping; Wu, Zhiwei; Feng, Juan; Zheng, Fei; Xu, Hanlie; Wang, Bin; Jin, Fei-Fei
The observational analysis shows that the relationship between the preceding winter El Niño-Southern Oscillation (ENSO) and the following East Asian summer monsoon (EASM) in the past 60 years is strengthened. Both the observational and numerical evidences demonstrate that spring North Atlantic Oscillation (NAO) may exert significant influences on the enhancement of the EASM-ENSO relationship. Anomalous spring NAO may cause a tripole SSTA pattern in North Atlantic which can persist into ensuring summer from spring. In summer, the tripole SSTA impacts EASM through two pathways. One is the tripole SSTA pattern excites the Atlantic-Eurasian (AEA) teleconnection which is a distinct Rossby wave train prevailing over the Atlantic and northern Eurasia. As a result, the blocking highs over the Ural Mountain and the Okhotsk Sea can be modulated. Another is it can force a simple Gill-Matsuno-type quadrupole response over western Pacific, consequently, the linkage between the western Pacific subtropical high (WPSH) and ENSO is enhanced. The co-effects of the two teleconnection patterns help to strengthen (or weaken) the subtropical Meiyu-Baiu-Changma front, the primary rain-bearing system of the EASM. As such, spring NAO is tied to the strengthened connection between ENSO and the EASM. Then we may establish a NAO-ENSO-based seasonal prediction model for EASM. The hindcast experiments show a good performances of this prediction model for EASM. The NAO-ENSO-based model is employed to make seasonal prediction for EASM strength and summer rainfall over middle reach of Yangtze river in 2012, and the results show a good performance of the approach, implying the model could be a useful tool for seasonal prediction of EASM.
An, Soon-Il; Kim, Hyo-Jeong; Park, Wonsun; Schneider, Birgit
Orbital forcing influences climate phenomena by changing incoming solar radiation in season and latitude. Here, changes in the El Niño-Southern Oscillation (ENSO)'s impact on the East Asian winter monsoon (EAWM) due to orbital forcing, especially for three selected time periods in each of two interglacial periods, the Eemian (126, 122, 115 ka) and Holocene (9, 6, 0 ka), are investigated. There was a high negative correlation between ENSO and EAWM when the obliquity was low, the processional angle was large, and especially when accompanied by large eccentricity, which corresponds to a weaker monsoon period. The correlation was also high when ENSO variability was high, which interestingly corresponded to lower obliquity and higher-degree precession periods. Therefore, as both lower obliquity and higher-degree precession, such as during 115 ka and 0 ka, cause the EAWM to be weakened through higher winter insolation over Northern hemisphere, and the ENSO to be enhanced through an intensified zonal contrast of the equatorial sea surface temperature, the relationship between the ENSO and EAWM becomes tighter. The opposite case (i.e., during 126 and 9 ka) is also true dynamically. Furthermore, the sensitivity of boreal winter precipitation against sea surface temperature (SST) anomaly over the tropical Pacific, which depends on mean SST, was positively correlated to the strength of the ENSO-EAWM correlation, implying that the warmer mean ocean surface causes the strong response of atmosphere to change in the SST anomaly, thereby enhancing the impact of ENSO on EAWM. Warmer wintertime tropical SST is attributed to higher insolation over the tropics, especially during 115 and 0 ka, while cooler SSTs occurred during 126 and 9 ka.
Yang, J H; Sohn, Y-H; Ko, S-Y; Choi, S-E; Kim, M H; Oh, H-B
Human leukocyte antigens (HLAs) are useful markers for anthropological investigations because the allele and haplotype distributions at these loci vary widely among ethnic groups. HLA frequencies in Koreans, however, have not previously been analyzed on a phylogenetic basis. We determined the allele frequencies of four HLA class II (HLA-DRB1, -DQA1, -DQB1, and -DPB1) loci in 149 unrelated Korean individuals using a sequence-based typing method. A total of 29 HLA-DRB1, 17 HLA-DQA1, 16 HLA-DQB1, and 15 HLA-DPB1 alleles were identified. The most common allele at each locus was DRB1*0901, DQA1*0102, DQB1*0301, and DPB1*0501, respectively. Four-locus allelic association analysis showed the existence of 25 DRB1-DQA1-DQB1-DPB1 haplotypes with a frequency greater than 0.010. A dataset comprising ethnicity-specific information from published literature and the dbMHC database, as well as the allele frequencies determined in this study, was subjected to phylogenetic analysis. The analysis showed that Koreans are most closely related to Japanese and Han Chinese from Shandong province. Correspondence analyses showed that the current Korean population is located in a position intermediate between the northern and southern East Asian groups, supporting the theory of a bi- and/or multidirectional route of migration of early Korean settlers. This report can be used for anthropological studies, and may also be of use in the International Hematopoietic Stem Cell Sharing program.
Introduction Incomplete lineage sorting and hybridization are two major nonexclusive causes of haplotype sharing between species. Distinguishing between these two processes is notoriously difficult as they can generate similar genetic signatures. Previous studies revealed that the mitochondrial DNA (mtDNA) differentiation between two East Asian long-tailed tits (Aegithalos bonvaloti and A. fuliginosus) was extremely low, even lower than intraspecific differentiation in some other long-tailed tits. Using a combination of multilocus and coalescent analyses, we explored the causes of the anomalous lack of mtDNA differentiation between the two species. Results The mtDNA divergence between the two species was shallow, while the nuclear DNA (nuDNA) divergence was considerably deeper. The IMa analyses based on the mtDNA dataset suggested relatively high gene flow from A. fuliginosus to A. bonvaloti, while negligible gene flow in the opposite direction. In contrast to mtDNA, the migration rates at autosomal and Z-linked nuDNA loci were negligible or much lower. The NEWHYBRIDS analysis assigned all individuals except one to pure parental species with high posterior probability. The Bayesian skyline plot showed that both species underwent population expansions during the Last Glacial Maximum (LGM), and the ecological niche modelling suggested that their ranges overlapped more during the LGM than at present. Conclusions We suggest that historical hybridization, in combination with selective sweep and/or genetic drift might be the main causes of the extremely low mtDNA differentiation between the two species. The hybridization probably occurred mainly between A. fuliginosus females and A. bonvaloti males. The LGM distribution expansion might have facilitated hybridization, while the post-LGM distribution contraction could have facilitated some mtDNA sorting. Ongoing hybridization between the two species might be very limited, but further studies with more samples from the
Kandasamy, S.; Chen, C. A.; Lou, J.
Sedimentary geochemical records from subalpine Retreat Lake, subtropical Taiwan, document the unstable East Asian Monsoon (EAM) climate for the last ~10250 calendar years before the present (cal yr B.P.). The proxy records demonstrate cool, glacial conditions with weak EAM between ~10250 and 8640 cal yr B.P., the strongest EAM during the "Holocene optimum" (8640-4500 cal yr B.P.) with an abrupt, decadal onset of postglacial EAM (8640-8600 cal yr B.P.), and relatively dry conditions since 4500 cal yr B.P. Although after 8600 cal yr B.P., EAM strength reduces gradually in response to the Northern Hemisphere summer insolation, heat and moisture transport and the development of late Holocene El-Niño-Southern Oscillation in the tropical Pacific appear to corroborate the periods of abrupt monsoon changes. Our proxy records reveal several weak monsoon intervals that correlate to low sea surface temperatures in the western tropical Pacific and cold events in the North Atlantic, suggesting a mechanistic link. Among those, four weak EAM events at 8170, 5400, 4500-2100 and 2000-1600 cal yr B.P. are in phase with the timings of low concentrations of atmospheric methane and periods of reduced North Atlantic Deep Water production as well as the `8.2 ka cold spell' and widespread event of low-latitude cultural collapse. Our EAM records exhibit strong correlations with high- and low-latitude climate and monsoon records; thus, provide robust evidences that the centennial-millennial scale monsoon variability during the Holocene are globally-mediated via sun- ocean-monsoon-North Atlantic linkages.
Wang, Lei; Asimakopoulos, Alexandros G; Moon, Hyo-Bang; Nakata, Haruhiko; Kannan, Kurunthachalam
Organic corrosion inhibitors (OCIs), including ultraviolet light filters, are widely used in plastics, rubbers, colorants, and coatings to increase the performance of products. Derivatives of benzotriazole (BTR), benzothiazole (BTH), and benzophenone (BP) are high-production volume OCIs that have been detected in the environment and human tissues. However, knowledge of their occurrence in indoor environments, as well as human exposure to them, is still lacking. In this study, BTR, BTH, BP and their 12 derivatives were determined in indoor dust for the first time. All three groups of OCIs were found in all 158 indoor dust samples from the U.S. and three East Asian countries (China, Japan, and Korea). The geometric mean (GM) concentration of the sum of six BTRs (GM CΣBTRs) ranged from 20 to 90 ng/g among the four countries studied, with a maximum CΣBTRs of ∼2000 ng/g found in a dust sample from China. Tolyltriazole was the major derivative of BTR measured in dust. GM CΣBTHs in indoor dust from the four countries ranged from 600 to 2000 ng/g. 2-OH-BTH was the predominant BTH in dust from the U.S., Japan, and Korea. GM CΣBPs in dust ranged from 80 to 600 ng/g, with 2-OH-4-MeO-BP and 2,4-2OH-BP, contributing to the majority of ∑BP concentrations. Based on the concentrations of three types of OCIs in indoor dust, human exposure through dust ingestion was calculated. Daily intake of OCIs through dust ingestion was higher for people in the U.S., Japan, and Korea than in China; the residents in urban China are exposed to higher levels of OCIs via dust ingestion than are those in rural China.
Takahara, Hikaru; Igarashi, Yaeko; Hayashi, Ryoma; Kumon, Fujio; Liew, Ping-Mei; Yamamoto, Masanobu; Kawai, Sayuri; Oba, Tadamichi; Irino, Tomohisa
High-resolution pollen records from Taiwan, Japan and Sakhalin document regional vegetation changes during Dansgaard-Oeschger (D-O) cycles during the last glacial. During the period from the cold phase (GS 18/19) to warm phase (D-O 19), the biome shift from temperate conifer forest to cold/cool conifer forest in Japan and from subtropical forest to temperate deciduous/conifer forest in Taiwan. The vegetation in D-O 17, cool mixed forest in central Japan, temperate deciduous broadleaf forest in western Japan and subtropical forest in Taiwan, indicates warm condition but not wet in all area. These vegetation changes lead to biome shift from MIS (Marine Isotope Stage) 4 to MIS 3. The abundance of Cryptomeria japonica and Fagus crenata in D-O 12 and D-O 8 indicates wet conditions brought by the strong summer monsoon through the Islands and high snowfall brought by the inflow of the Tsushima Warm Current into the Sea of Japan. The registration of other D-O warming events in MIS 3, although reflected by shifts in the abundance of key species, is not sufficient to produce changes in biomes. Development of cold deciduous forest in HS (Heinrich events) 1 in Sakhalin, Hokkaido and central Japan was conspicuous and was much larger than that in YD. Vegetation response in YD was small scale and within the same biome in the East Asian Islands. In D-O 1 at the termination of the last glacial, the same taxa that developed in the early Holocene, cold evergreen needleleaf trees in northern region, temperate deciduous broadleaf trees in central and western Japan, and warm-temperate evergreen trees in Taiwan, increased.
Sun, Li; Shen, Baizhu; Sui, Bo; Huang, Bohua
A unique dataset of 53-year (1961-2013) rainfall measurements from 104 stations uniformly distributed in the Northeast China, combined with the observation-based NCEP/NCAR atmospheric reanalysis, is used to analyze the precipitation anomalies in Northeast China during late boreal summer (July-August) and their relationship with the anomalous moisture transport associated with the fluctuations of the East Asian Summer Monsoon (EASM) circulation. Based on this analysis, a new EASM influence index (I EASM ) is proposed to quantify the EASM effects on the Northeast China summer precipitation. The relationship between the IEASM variations and patterns of the anomalous regional atmospheric circulation is demonstrated. The characteristics of several precursors that lead to the major fluctuations of the I EASM index are also explored. The results show that the EASM influence index is closely linked to the anomalous rainfall in Northeast China and can be used as a major factor to measure the physical processes that affect the regional dry and wet conditions. The I EASM index responds to the large-scale anomalies of the atmospheric circulation sensitively. Specifically, the high I EASM values are associated with the intensified Mongolia cyclone, blocking developing near the Ural Mountains and a northwestward shift of subtropical high over the western Pacific. The low I EASM values are associated with a reversed pattern of these features. The I EASM anomalous fluctuation has some precursors. A major high (low) index during the summer is likely preceded with the pattern of the sea surface temperature anomalies of an El Niño (La Niña) event in the Pacific from the previous early fall to early winter.
Geng, Xin; Zhang, Wenjun; Stuecker, Malte F.; Liu, Peng; Jin, Fei-Fei; Tan, Guirong
This work investigates the decadal modulation of the El Niño-Southern Oscillation (ENSO)-East Asian winter monsoon (EAWM) relationship by the Atlantic Multidecadal Oscillation (AMO). A stable ENSO-EAWM relationship is found during the positive AMO phase but not during the negative phase. While the impact of El Niño events on the EAWM does not depend on the AMO phase, a different picture is observed for La Niña events. The La Niña boreal winter season coincides with a strengthened EAWM during a positive AMO phase and a weakened EAWM during a negative AMO phase. We suggest that the AMO's modulating effect mainly comprises two pathways that influence ENSO's impact on the EAWM. On one hand, when La Niña coincides with a positive AMO, the warm SST anomalies over the western North Pacific (WNP) are amplified both in intensity and spatial extent, which favors strengthened WNP cyclonic anomalies and an enhanced EAWM. During La Niña with a negative AMO, only very weak SST anomalies occur over the WNP with reduced WNP cyclonic anomalies that are confined to the tropics, thus having little effect on the EAWM. On the other hand, an eastward-propagating Rossby wavetrain across the mid-high latitudes of Eurasia during a warm AMO phase strengthens the Siberian high and thus leads to a strengthened EAWM, while during a cold AMO phase the Siberian high is weakened, leading to a reduced EAWM. In contrast, El Niño and its associated atmospheric responses are relatively strong and stable, independent of the AMO phase. These results carry important implications to the seasonal-to-interannual predictability associated with ENSO.
The health systems of Japan and the Asian Tigers (Hong Kong, Korea, Singapore and Taiwan), and the recent reforms to them, provide many potentially valuable lessons to East Asia's developing countries. All five systems have managed to keep a check on health spending despite their different approaches to financing and delivery. These differences are reflected in the progressivity of health finance, but the precise degree of progressivity of individual sources and the extent to which households are vulnerable to catastrophic health payments depend on the design features of the system - the height of any ceilings on social insurance contributions, the fraction of health spending covered by the benefit package, the extent to which the poor face reduced copayments, whether there are caps on copayments, and so on. On the delivery side, too, Japan and the Tigers offer some interesting lessons. Singapore's experience with corporatizing public hospitals - rapid cost and price inflation, a race for the best technology, and so on - illustrates the difficulties of corporatization. Korea's experience with a narrow benefit package illustrates the danger of providers shifting demand from insured services with regulated prices to uninsured services with unregulated prices. Japan, in its approach to rate setting for insured services, has managed to combine careful cost control with fine-tuning of profit margins on different types of care. Experiences with DRGs in Korea and Taiwan point to cost-savings but also to possible knock-on effects on service volume and total health spending. Korea and Taiwan both offer important lessons for the separation of prescribing and dispensing, including the risks of compensation costs outweighing the cost savings caused by more 'rational' prescribing, and cost-savings never being realized because of other concessions to providers, such as allowing them to have onsite pharmacists.
Liu, Xiaoxi; Shimada, Takafumi; Otowa, Takeshi; Wu, Yu-Yu; Kawamura, Yoshiya; Tochigi, Mamoru; Iwata, Yasuhide; Umekage, Tadashi; Toyota, Tomoko; Maekawa, Motoko; Iwayama, Yoshimi; Suzuki, Katsuaki; Kakiuchi, Chihiro; Kuwabara, Hitoshi; Kano, Yukiko; Nishida, Hisami; Sugiyama, Toshiro; Kato, Nobumasa; Chen, Chia-Hsiang; Mori, Norio; Yamada, Kazuo; Yoshikawa, Takeo; Kasai, Kiyoto; Tokunaga, Katsushi; Sasaki, Tsukasa; Gau, Susan Shur-Fen
Autism spectrum disorder is a heterogeneous neurodevelopmental disorder with strong genetic basis. To identify common genetic variations conferring the risk of ASD, we performed a two-stage genome-wide association study using ASD family and healthy control samples obtained from East Asian populations. A total of 166 ASD families (n = 500) and 642 healthy controls from the Japanese population were used as the discovery cohort. Approximately 900,000 single nucleotide polymorphisms (SNPs) were genotyped using Affymetrix Genome-Wide Human SNP array 6.0 chips. In the replication stage, 205 Japanese ASD cases and 184 healthy controls, as well as 418 Chinese Han trios (n = 1,254), were genotyped by TaqMan platform. Case-control analysis, family based association test, and transmission/disequilibrium test (TDT) were then conducted to test the association. In the discovery stage, significant associations were suggested for 14 loci, including 5 known ASD candidate genes: GPC6, JARID2, YTHDC2, CNTN4, and CSMD1. In addition, significant associations were identified for several novel genes with intriguing functions, such as JPH3, PTPRD, CUX1, and RIT2. After a meta-analysis combining the Japanese replication samples, the strongest signal was found at rs16976358 (P = 6.04 × 10(-7)), which is located near the RIT2 gene. In summary, our results provide independent support to known ASD candidate genes and highlight a number of novel genes warranted to be further investigated in a larger sample set in an effort to improve our understanding of the genetic basis of ASD.
Argent, Richard H; Hale, James L; El-Omar, Emad M; Atherton, John C
Helicobacter pylori strains from East Asia have an 'East Asian' type of CagA that is more active and predominantly comprises a single type. Strains from other countries have a 'western' type of CagA, which is less active and comprises many different types generated by intragenomic recombination. Co-culture of AGS gastric epithelial cells with isolates of western strains that displayed microevolution in CagA showed that isolates with additional copies of the C motif induced significantly more interleukin (IL)-8 secretion. Co-culture of AGS cells with western and East Asian strains, each expressing CagA with a single copy of the C or D motif, showed that East Asian strains induced significantly more IL-8 secretion. Analysis of the different CagA types from data deposited in GenBank and from the literature showed that western CagA is significantly more likely to undergo duplication of tyrosine phosphorylation motif C than East Asian CagA is of the corresponding D motif. Taken together, the data suggest that the already highly active East Asian CagA with one D motif has no requirement to increase its virulence, whereas the less active western CagA displays flexibility in its capacity to increase its number of tyrosine phosphorylation motifs to become more virulent.
Zhou, Ningfang; Yu, Yongqiang; Qian, Yongfu
The South Asian High (SAH) and precipitation over East Asia simulated by 11 coupled GCMs associated with the forthcoming Intergovernmental Panel on Climate Change’s (IPCC) 4th Assessment Report are evaluated. The seasonal behavior of the SAH is presented for each model. Analyses of the results show that all models are able to reproduce the seasonal cycle of the SAH. Locations of the SAH center are also basically reproduced by these models. All models underestimate the intensity and the extension of coverage in summer. The anomalous SAH can be divided into east and west modes according to its longitudinal position in summer on the interannual timescale, and the composite anomalies of the observed precipitation for these two modes tend to have opposite signs over East Asia. However, only several coupled GCMs can simulate the relationship between rainfall and SAH similar to the observed one, which may be associated with the bias in simulation of the subtropical anticyclone over the West Pacific (SAWP) at 500 hPa. In fact, it is found that any coupled GCM, that can reproduce the reasonable summer mean state of SAWP and the southward (northward) withdrawal (extension) for the east (west) mode of SAH as compared to the observed, will also simulate similar rainfall anomaly patterns for the east and west SAH modes over East Asia. Further analysis indicates that the observed variations in the SAH, SAWP and rainfall are closely related to the sea surface temperature (SST) over the equatorial tropical Pacific. Particularly, some models cannot simulate the SAWP extending northward in the west mode and withdrawing southward in the east mode, which may be related to weak major El Niño or La Niña events. The abilities of the coupled GCMs to simulate the SAWP and ENSO events are associated partly with their ability to reproduce the observed relationship between SAH and the rainfall anomaly over East Asia.
Yin, Hengxia; Yan, Xia; Shi, Yong; Qian, Chaoju; Li, Zhonghu; Zhang, Wen; Wang, Lirong; Li, Yi; Li, Xiaoze; Chen, Guoxiong; Li, Xinrong; Nevo, Eviatar; Ma, Xiao-Fei
Both of the uplift of Qinghai-Tibet Plateau (QTP) and the development of East Asian monsoon system (EAMS) could have comprehensively impacted the formation and evolution of Arid Central Asia (ACA). To understand how desert plants endemic to ACA responded to these two factors, we profiled the historical population dynamics and distribution range shift of a constructive desert shrub Reaumuria soongarica (Tamaricaceae) based on species wide investigation of sequence variation of chloroplast DNA and nuclear ribosomal ITS. Phylogenetic analysis uncovered a deep divergence occurring at ca. 2.96 Mya between the western and eastern lineages of R. soongarica, and ecological niche modeling analysis strongly supported that the monsoonal climate could have fragmented its habitats in both glacial and interglacial periods and impelled its intraspecific divergence. Additionally, the population from the east monsoonal zone expanded rapidly, suggesting that the local monsoonal climate significantly impacted its population dynamics. The isolation by distance tests supported strong maternal gene flow along the direction of the East Asian winter monsoon, whose intensification induced the genetic admixture along the latitudinal populations of R. soongarica. Our results presented a new case that the development of EAMS had prominently impacted the intraspecific divergence and population dynamics of this desert plant. PMID:26510579
Yin, Hengxia; Yan, Xia; Shi, Yong; Qian, Chaoju; Li, Zhonghu; Zhang, Wen; Wang, Lirong; Li, Yi; Li, Xiaoze; Chen, Guoxiong; Li, Xinrong; Nevo, Eviatar; Ma, Xiao-Fei
Both of the uplift of Qinghai-Tibet Plateau (QTP) and the development of East Asian monsoon system (EAMS) could have comprehensively impacted the formation and evolution of Arid Central Asia (ACA). To understand how desert plants endemic to ACA responded to these two factors, we profiled the historical population dynamics and distribution range shift of a constructive desert shrub Reaumuria soongarica (Tamaricaceae) based on species wide investigation of sequence variation of chloroplast DNA and nuclear ribosomal ITS. Phylogenetic analysis uncovered a deep divergence occurring at ca. 2.96 Mya between the western and eastern lineages of R. soongarica, and ecological niche modeling analysis strongly supported that the monsoonal climate could have fragmented its habitats in both glacial and interglacial periods and impelled its intraspecific divergence. Additionally, the population from the east monsoonal zone expanded rapidly, suggesting that the local monsoonal climate significantly impacted its population dynamics. The isolation by distance tests supported strong maternal gene flow along the direction of the East Asian winter monsoon, whose intensification induced the genetic admixture along the latitudinal populations of R. soongarica. Our results presented a new case that the development of EAMS had prominently impacted the intraspecific divergence and population dynamics of this desert plant.
Zhang, Jingyong; Wu, Lingyun; Huang, Gang; Zhu, Wenquan; Zhang, Yan
It is well known that the slowly varying oceanic processes provide the primary source for East Asian summer monsoon (EASM) predictability. However, the memory inherent in the land surface state is less well understood or applied toward the EASM prediction. Here we investigate the role of antecedent vegetation conditions over East Asia for the EASM variation and prediction using March, April, May, and spring mean satellite-sensed Normalized Difference Vegetation Index (NDVI) for the period of 1982-2006. Results show that May vegetation greenness on the southeastern Tibetan Plateau (TP) is most closely linked to the EASM, accounting for about half of the total EASM variance. May vegetation greenness on the southeastern TP has significant and positive correlations with summer rainfall over the southeastern TP, East Asian summer subtropical frontal region, and many areas of northern China. We further discuss the possible physical mechanism explaining our findings. It is proposed that increased TP vegetation greenness enhances surface thermal effects, which subsequently warm atmospheric temperature, as well as strengthen ascending motion, convergence at the lower layers and divergence at the higher layers, and summer monsoon circulation. Finally, a linear regression model is developed to predict the EASM strength by combination of El Niño-Southern Oscillation (ENSO) and the vegetation greenness. Hindcast for the period 1982-2006 shows that the use of the southeastern TP vegetation information can highly improve the EASM prediction skill compared to that using ENSO alone.
Lin, Ka; Xu, Yun; Huang, Tianhai; Zhang, Jiahua
Using data from surveys on "social quality survey questionnaires", carried out by the Asian Consortium for Social Quality between 2009 and 2011, this study investigates the causes of social exclusion in six Asian societies. About 6,460 questionnaires were completed and the analysis of the data reveals the features and the causes of…
Despite their educational and economic achievements in the United States, Asian Americans continue to be occupationally segregated in the labor force. Asian Americans are overrepresented in mathematics, engineering and biological sciences while underrepresented in field such as education, humanities, social and behavioral sciences (Bureau of Labor…
Borucki, Monica K.; Lao, Victoria; Hwang, Mona; ...
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging human pathogen related to SARS virus. In vitro studies indicate this virus may have a broad host range suggesting an increased pandemic potential. Genetic and epidemiological evidence indicate camels serve as a reservoir for MERS virus but the mechanism of cross species transmission is unclear and many questions remain regarding the susceptibility of humans to infection. Deep sequencing data was obtained from the nasal samples of three camels that had been experimentally infected with a human MERS-CoV isolate. A majority of the genome was covered and average coverage was greater thanmore » 12,000x depth. Although only 5 mutations were detected in the consensus sequences, 473 intrahost single nucleotide variants were identified. Lastly, many of these variants were present at high frequencies and could potentially influence viral phenotype and the sensitivity of detection assays that target these regions for primer or probe binding.« less
Wang, Zhili; Zhang, Hua; Zhang, Xiaoye
The response of the East Asian summer monsoon (EASM) system to reductions in emissions of anthropogenic aerosols and their precursors at the end of the twenty-first century projected by Representative Concentration Pathway 4.5 is studied using an aerosol-climate model with aerosol direct, semi-direct, and indirect effects included. Our results show that the global annual mean aerosol effective radiative forcing at the top of the atmosphere (TOA) is +1.45 W m-2 from 2000 to 2100. The summer mean net all-sky shortwave fluxes averaged over the East Asian monsoon region (EAMR) at the TOA and surface increased by +3.9 and +4.0 W m-2, respectively, due to the reductions of aerosols in 2100 relative to 2000. Changes in radiations affect local thermodynamic and dynamic processes and the hydrological cycle. The summer mean surface temperature and pressure averaged over the EAMR are shown to increase by 1.7 K and decreased by 0.3 hPa, respectively, due to the reduced aerosols. The magnitudes of these changes are larger over land than ocean, causing a marked increase in the contrast of land-sea surface temperature and pressure in the EAMR, thus strengthening the EASM. The summer mean southwest and south winds at 850 hPa are enhanced over eastern and southern China and the surrounding oceans, and the East Asian subtropical jet shifted northward due to the decreases of aerosols. These factors also indicate enhanced EASM circulation, which in turn causes a 10 % increase in summer mean precipitation averaged over the EAMR.
Liu, Z.; Li, X.; He, Z.; Colin, C.; Zhao, Y.
Clay minerals have a significant role in sedimentation and paleoenvironment studies of the South China Sea. Many previous studies showed that the time series variation in late Quaternary clay mineral assemblages presents mostly glacial-interglacial cyclicity, and they were interpreted chemical weathering closely related to contemporaneous climatic changes of source areas. It is quite debatable whether clay minerals can directly indicate the East Asian monsoon evolution. To answer this question, we investigated sediment cores collected in various locations in the South China Sea during the MARCO POLO cruise in 2005, MD05-2904 (2066 m water depth, abbreviated w.d.) and MD05-2905 (1198 m w.d.) in the north, MD05-2901 (1254 m w.d.) and MD05-2899 (2393 m w.d.) in the west, and MD05-2895 (1982 m w.d.) in the south. Our results show that provenance supply and current transport directly control the clay mineralogical compositions in core and surface sediments, with various expression forms in different locations. In the north, the clay mineral assemblage indicates a relationship between surface current transport (for smectite) under the significant influence of the Kuroshio intrusion and deep water transport (for illite and chlorite). In the west, the East Asian monsoons forced surface currents and different clay-composition provenances affect the glacial-interglacial cyclicity of clay mineral variations. In the south, land-sea distribution variations controlled by the sea level change determine the sources of clay minerals. Our new studies suggest that the late Quaternary clay minerals in the South China Sea do not bear contemporaneous paleoclimatic features, and their implication for proxies of the East Asian monsoon evolution is realized through both the provenance supply and current transport processes.
Yuan, Xiao-Yan; Yan, Jin-Jun; Yang, Ya-Chao; Wu, Chun-Mei; Hu, Yan; Geng, Jian-Li
The severity of Helicobacter pylori-related disease is correlated with the presence and integrity of a cag pathogenicity island (cagPAI). cagPAI genotype may have a modifying effect on the pathogenic potential of the infecting strain. After analyzing the sequences of cagPAI genes, some strains with the East Asian-type cagPAI genes were selected for further analysis to examine the association between the diversity of the cagPAI genes and the virulence of H. pylori. The results showed that gastric mucosal inflammatory cell infiltration was significantly higher in patients with East Asian-type cagPAI genes H. pylori strain compared with mosaicism cagPAI genes H. pylori strain (p<0.05). H. pylori strains with the East Asian-type cagPAI genes were closely associated with IL-8 secretion in vitro and in vivo compared with H. pylori strains with the mosaicism cagPAI genes (p<0.01). H. pylori strains with East Asian-type cagPAI genes are able to strongly translocate CagA to host cells. These results suggest that H. pylori strains with East Asian-type cagPAI genes are more virulent than the strains of cagPAI gene/genes that are Western type.
Yunnan province, China is a typical area that is influenced by Southwest Asian summer monsoon (SASM) during boreal summer. Although the interannual variation of summer precipitation in Yunnan Province is closely related to that of the SASM, the East Asian subtropical westerly jet (EASWJ) may have an important role in heavy rainfall events in Yunnan Province during boreal summer. By using daily observations and the NACAR/NCEP data during 1960-2011, a diagnostic analysis is performed to investigate the association of the EASWJ with the SASM on heavy rain events in Yunnan Province during boreal summer. The analysis shows an anomalous divergence circulation pattern at upper level (200 hPa) over Eurasian continent that corresponds well to the negative anomaly of EASWJ during heavy rain events in boreal summer in Yunnan Province. At the same time, a low-level jet stream with abundant water vapor originated from the Arabian Sea and Bengal gulf provides necessarily dynamic and water conditions for heavy rain mechanism. The study further shows that the weakening of the EASWJ during heavy rain events in Yunnan Province is associated with the decrease in the meridional temperature gradient in northern mid-latitude (30o-40o N).
Ge, J.; Dai, Y.; Zhang, Z.; Zhao, D.; Li, Q.; Zhang, Y.; Yi, L.; Oldfield, F.; Guo, Z.
Since the mid-Pliocene, East Asian climates have experienced significant changes. One view suggests that significant uplift of the Tibetan Plateau during this period could have been responsible for these dramatic changes in the strength of the East Asian monsoon and for Asian interior aridification, while some other authors attribute these changes to the ongoing global cooling and rapid growth of the Arctic ice-sheet. Up to the present, which factor dominates the major changes of East Asian climate in the mid-Pliocene is still a contentious issue. This study presents an analysis of several climate proxies including magnetic susceptibility, grain-size, (CaO*+Na2O+MgO)/TiO2 ratio, Na/Ka ratio, Fe flux, and dust accumulation rates of the Xifeng Red Clay sequence in the eastern Chinese Loess Plateau and the Xihe Pliocene loess-soil sequence in West Qinling. They reveal that aridity in the continental interior and winter monsoon circulation both intensified, whereas the East Asian summer monsoon showed a weakening rather than intensifying trend since the mid-Pliocene. These changes are also supported by the other multi-proxy records from various regions in East Asia. Previous numerical modeling studies have demonstrated that uplift of the Tibetan Plateau would have simultaneously enhanced continental-scale summer and winter monsoon strength as well as central Asian aridity. The mid-Pliocene climate changes in East Asia are therefore unlikely to be a response to Plateau uplift. On the contrary, our recent modeling results give support to the view that ongoing cooling could have intensified both the aridity of the interior and the strength of the winter monsoon, but weakened the summer monsoon in East Asia.
Yamaguchi, Tetsutaro; Tomita, Daisuke; Nakawaki, Takatoshi; Kim, Yong-Il; Hikita, Yu; Haga, Shugo; Takahashi, Masahiro; Nadim, Mohamed A.; Kawaguchi, Akira; Isa, Mutsumi; El-Kenany, Walid H.; El-Kadi, Abbadi A.; Park, Soo-Byung; Ishida, Hajime; Maki, Koutaro; Kimura, Ryosuke
FGFR1 plays an important role in the development of the nervous system as well as the regulation of the skeletal development and bone homeostasis. Mutations in FGFR1 genes affect skull development, specifically suture and synchondrosis, resulting in craniosynostosis and facial abnormalities. We examined subjects with normal skull morphology for genetic polymorphisms that might be associated with normal craniofacial variations. Genomic DNA was obtained from 216 Japanese and 227 Korean subjects. Four FGFR1 SNPs, namely, rs881301, rs6996321, rs4647905, and rs13317, were genotyped. These SNPs were tested for association with craniofacial measurements obtained from lateral and posteroanterior cephalometries, in which principle component analysis was performed to compress the data of the craniofacial measurements. We observed that SNPs rs13317 and rs6996321 were correlated with the overall head size and midfacial development, indicating that FGFR1 SNPs played crucial roles in the normal variation of human craniofacial morphology. Subjects with the derived alleles of SNPs rs13317 and rs6996321 had a small face and a facial pattern associated with a retruded midface and relatively wide-set eyes. These facial features were similar to but were milder than those of individuals with Pfeiffer syndrome, which is caused by a dysfunctional mutation in FGFR1. PMID:28129408
Robinson, N. H.; Allan, J. D.; Williams, P. I.; Coe, H.; Hamilton, J.; Chen, Q.; Martin, S.; Trembath, J.
The tropics emit a huge amount of volatile organic compounds (VOCs) into the Earth's atmosphere. The processes by which these gases are oxidised to form secondary organic aerosol (SOA) are currently not well understood or quantified. Intensive field measurements were carried out as part of the Oxidant and Particle Photochemical Processes (OP3) and the Aerosol Coupling in the Earth System (ACES) projects around pristine rainforest in Malaysian Borneo. This is the first campaign of its type in a South East Asian rainforest. We present detailed organic aerosol composition measurements made using an Aerodyne High Resolution Time of Flight Aerosol Mass Spectrometer (HR-ToF-AMS) at Bukit Atur, a Global Atmosphere Watch site located in the Danum Valley Conservation Area. This is a state-of-the-art field deployable instrument that can provide real time composition, mass loading and aerodynamic particle sizing information. In addition, the mass spectral resolution is sufficient to perform an analysis of the elemental composition of the organic species present. Other tools such as positive matrix factorisation (PMF) have been used to help assess the relative source contributions to the organic aerosol. A suite of supporting aerosol and gas phase measurements were made, including size resolved number concentration measurements with Differential Mobility Particle Sizer (DMPS), as well as absorption measurements made with a Multi-Angle Absorption Photometer (MAAP). The ground site data are compared with Aerodyne Compact Time of Flight Aerosol Mass Spectrometer (C-ToF-AMS) measurements made on the UK Facility for Airborne Atmospheric Measurements (FAAM) BAe-146 research aircraft. Airborne measurements were made above pristine rainforest surrounding the Danum Valley site, as well as nearby oil palm agricultural sites and palm oil rendering plants. Airborne hygroscopicity was measured using a Droplet Measurement Technology Cloud Condensation Nuclei counter (DMT CCN counter) in
Muller, Jennifer; Coyle, Mhairi; Helfter, Carole; Dorsey, James; Gallagher, Martin; Percival, Carl; Nemitz, Eiko; Fowler, David
Ozone flux measurements were made over a South-East Asian tropical rainforest (April & June/July 2008) and an oil palm plantation (June 2008), as part of the NERC OP3 and ACES projects. Flux measurements over the rainforest were made at the Bukit Atur Global Atmospheric Watch (GAW) tower, where ozone fluxes were measured by the gradient approach (concentrations at 30, 45, 60, 75 m) and by eddy-covariance (45 and 75 m). The hourly median flux at the forest site peaked before midday and did not differ greatly between Period 1 (P1, April, end of wet season) and Period 3 (P3, June/July, dry season). The periods were however clearly contrasted by the different levels of ambient ozone and concentrations were larger during P1 by about 50 %, with diurnal hourly medians ranging from 26 - 38 ?g m-3 in P1 versus 15 - 27 ?g m-3 in P3. Ozone deposition velocities were smaller during P1 than P3 and median daytime maxima of deposition velocity in P1 were 5 mm s-1 compared to 11 mm s-1 in P3. The magnitude of fluxes and deposition velocities are similar to those observed over the Amazon rainforest (Rummel et al., 2007), but the diurnal profile differs slightly as ozone concentrations showed a stronger diurnal amplitude in the Amazon. Fluxes from 45 and 75 m are compared and ozone flux divergence with height is investigated. Flux measurements at the oil palm plantation were made using the eddy covariance method for 8 days (4th to 11th June 2008). During this period concentrations were very small with a diurnal range of 0 - 7 ?g m-3, probably due to the combined effect of a low measurement height, low turbulence and O3 destruction by soil NO emissions. However, median deposition velocity was 5 mm s-1 indicating that the oil palms are an effective sink for ozone. The ozone flux will be decomposed into stomatal ozone uptake by the vegetation, estimated from conductance modelling, ozone destruction by VOC chemistry (estimated from the measured VOC concentrations) and ozone destruction
Kim, Ji-Won; An, Soon-Il; Jun, Sang-Yoon; Park, Hey-Jin; Yeh, Sang-Wook
Using observational datasets and numerical model experiments, the mechanism on the slowly varying change in the relationship between the El Niño-Southern Oscillation (ENSO) and the East Asian winter monsoon (EAWM) is investigated. The decadal-window (11-, 15-, and 21-year) moving correlations show a significant change in the boreal wintertime ENSO-EAWM relationship between two sub-periods of 1976‒1992 and 1997‒2013. Such recent change in ENSO-EAWM relationship is mainly attributed to the changes in the intensity and zonal location of the anomalous lower-tropospheric northwest Pacific anticyclone (NWP-AC). NWP-AC commonly develops near the region of the Philippine Sea during the ENSO's peak phase and plays an important role of bridging the tropical convection and mid-latitude teleconnection. On one hand, the intensity of the NWP-AC is influenced by the interdecadal variation in a linkage between ENSO and the Indian Ocean sea surface temperature (SST) variability, referring that a strong connection between the Pacific and Indian Oceans results in the strengthening of NWP-AC response to ENSO. On the other hand, the zonal displacement of the NWP-AC is associated with the Pacific Decadal Oscillation (PDO) and the Atlantic Multidecadal Oscillation (AMO). That is, the tropical Pacific mean state (i.e., zonal SST gradient between climatologically warm western Pacific and cold eastern Pacific)—strengthened by either the negative PDO phase or the positive AMO phase—drives the anomalous ENSO-induced convection to be shifted to the west. With this westward shift, the zonal center of the NWP-AC also migrates westward over the Philippine Islands and exerts stronger connection between ENSO and EAWM. In contrast, the relaxed zonal SST contrast associated with either the positive PDO phase or the negative AMO phase tends to exhibit weaker ENSO-EAWM relationship via both of eastward shifted zonal centers of the anomalous ENSO-induced convection and the NWP-AC. Finally, a
Liu, Jianbao; Chen, Jianhui; Zhang, Xiaojian; Chen, Fahu
Monsoon precipitation over China exhibits large spatial differences. It has been found that a significantly enhanced East Asian summer monsoon (EASM) is characterized by increased rainfall in northern China and by reduced rainfall in southern China, and this relationship occurs on different time scales during the Holocene. This study presents results from a diverse range of proxy paleoclimatic records from northern China where precipitation variability is traditionally considered as an EASM proxy. Our aim is to evaluate the evolution of the EASM during the Holocene and to compare it with all of the published stalagmite δ18O records from the Asian Monsoon region in order to explore the potential mechanism(s) controlling the Chinese stalagmite δ18O. We found that the intensity of the EASM during the Holocene recorded by the traditional EASM proxy of moisture (or precipitation) records from northern China are significantly different from the Chinese stalagmite δ18O records. The EASM maximum occurred during the mid-Holocene, challenging the prevailing view of an early Holocene EASM maximum mainly inferred from stalagmite δ18O records in eastern China. In addition, all of the well-dated Holocene stalagmite δ18O records, covering a broad geographical region, exhibit a remarkably similar trend of variation and are statistically well-correlated on different time scales, thus indicating a common signal. However, in contrast with the clear consistency in the δ18O values in all of the cave records, both instrumental and paleoclimatic records exhibit significant spatial variations in rainfall on decadal-to- centennial time scales over eastern China. In addition, both paleoclimatic records and modeling results suggest that Holocene East Asian summer monsoon precipitation reached a maximum at different periods in different regions of China. Thus the stalagmite δ18O records from the EASM region should not be regarded as a reliable indicator of the strength of the East
Karami, M.; Herold, N.; Yin, Q.; Berger, A.
Studying past climates is a valuable approach to improve our understanding of the present and future climate systems. Among the significant events in the history of climate, the interglacial periods are good candidates for representation of the future climate because of their astronomical characteristics and their similarity to predicted anthropogenic warming. Moreover, some interglacials exhibited significant changes in atmospheric and oceanic properties due to only small changes in their climatic forcing (greenhouse gases and solar insolation) which also make them a good case for investigating past climates. For instance, the interglacial stage of around 0.5 Ma identified as Marine Isotopic stage 13 (MIS-13), the focus of this study, was characterized by extremely strong East Asian and Indian summer monsoons while the CO2 and CH4 levels were lower and seasonal radiation energy could reach up to 50 Wm-2 higher than today. The extreme monsoon precipitation is quite unexpected for a climate with such forcing. To understand the physics-based mechanism that enhances the East Asian Summer Monsoon (EASM) during MIS-13, we used two fully coupled general circulation models, the HadCM3 and CCSM3. In MIS-13 experiments, concentrations of greenhouse gases were prescribed lower than in pre-industrial and seasonal insolation characterised by Northern-Hemisphere (NH) summer occurring at perihelion instead of aphelion as it does today. Results of both models confirm increased summer precipitation in the monsoon regions. We find that the tropical Pacific Ocean plays a major role in strengthening the EASM in MIS-13. Simulations of MIS-13 show stronger easterly surface winds along the equatorial Pacific and a subsequent increase in the mean thermocline tilt, in addition to a westward shift of the cold tongue. These changes alter the background climatic state of the equatorial Pacific towards a La Niña-type state. The interannual variability around the La Niña-like background
This thesis aims at enhancing our fundamental understanding of the East Asian summer monsoon (EASM), and mechanisms implicated in its climatology in present-day and warmer climates. We focus on the most prominent feature of the EASM, i.e., the so-called Meiyu-Baiu (MB), which is characterized by a well-defined, southwest to northeast elongated quasi-stationary rainfall band, spanning from eastern China to Japan and into the northwestern Pacific Ocean in June and July. We begin with an observational study of the energetics of the MB front in present-day climate. Analyses of the moist static energy (MSE) budget of the MB front indicate that horizontal advection of moist enthalpy, primarily of dry enthalpy, sustains the front in a region of otherwise negative net energy input into the atmospheric column. A decomposition of the horizontal dry enthalpy advection into mean, transient, and stationary eddy fluxes identifies the longitudinal thermal gradient due to zonal asymmetries and the meridional stationary eddy velocity as the most influential factors determining the pattern of horizontal moist enthalpy advection. Numerical simulations in which the Tibetan Plateau (TP) is either retained or removed show that the TP influences the stationary enthalpy flux, and hence the MB front, primarily by changing the meridional stationary eddy velocity, with reinforced southerly wind on the northwestern flank of the north Pacific subtropical high (NPSH) over the MB region and northerly wind to its north. Changes in the longitudinal thermal gradient are mainly confined to the near downstream of the TP, with the resulting changes in zonal warm air advection having a lesser impact on the rainfall in the extended MB region. Similar mechanisms are shown to be implicated in present climate simulations in the Couple Model Intercomparison Project - Phase 5 (CMIP5) models. We find that the spatial distribution of the EASM precipitation simulated by different models is highly correlated
Chua, Chong-Long; Sam, I-Ching; Merits, Andres; Chan, Yoke-Fun
Background Chikungunya virus (CHIKV) is a re-emerging mosquito-borne virus which causes epidemics of fever, severe joint pain and rash. Between 2005 and 2010, the East/Central/South African (ECSA) genotype was responsible for global explosive outbreaks across India, the Indian Ocean and Southeast Asia. From late 2013, Asian genotype CHIKV has caused outbreaks in the Americas. The characteristics of cross-antibody efficacy and epitopes are poorly understood. Methodology/Principal Findings We characterized human immune sera collected during two independent outbreaks in Malaysia of the Asian genotype in 2006 and the ECSA genotype in 2008–2010. Neutralizing capacity was analyzed against representative clinical isolates as well as viruses rescued from infectious clones of ECSA and Asian CHIKV. Using whole virus antigen and recombinant E1 and E2 envelope glycoproteins, we further investigated antibody binding sites, epitopes, and antibody titers. Both ECSA and Asian sera demonstrated stronger neutralizing capacity against the ECSA genotype, which corresponded to strong epitope-antibody interaction. ECSA serum targeted conformational epitope sites in the E1-E2 glycoprotein, and E1-E211K, E2-I2T, E2-H5N, E2-G118S and E2-S194G are key amino acids that enhance cross-neutralizing efficacy. As for Asian serum, the antibodies targeting E2 glycoprotein correlated with neutralizing efficacy, and I2T, H5N, G118S and S194G altered and improved the neutralization profile. Rabbit polyclonal antibody against the N-terminal linear neutralizing epitope from the ECSA sequence has reduced binding capacity and neutralization efficacy against Asian CHIKV. These findings imply that the choice of vaccine strain may impact cross-protection against different genotypes. Conclusion/Significance Immune serum from humans infected with CHIKV of either ECSA or Asian genotypes showed differences in binding and neutralization characteristics. These findings have implications for the continued
Wei, Ting; Wang, Lanning; Dong, Wenjie; Dong, Min; Zhang, Jingyong
This paper examines the sensitivity of CAM3.1 simulations of East Asian summer monsoon (EASM) to the choice of dynamic cores using three long-term simulations, one with each of the following cores: the Eulerian spectral transform method (EUL), semi-Lagrangian scheme (SLD) and finite volume approach (FV). Our results indicate that the dynamic cores significantly influence the simulated fields not only through dynamics, such as wind, but also through physical processes, such as precipitation. Generally speaking, SLD is superior to EUL and FV in simulating the climatological features of EASM and its interannual variability. The SLD version of the CAM model partially reduces its known deficiency in simulating the climatological features of East Asian summer precipitation. The strength and position of simulated western Pacific subtropical high (WPSH) and its ridge line compare more favourably with observations in SLD and FV than in EUL. They contribute to the intensification of the south-easterly along the south of WPSH and the vertical motion through the troposphere around 30° N, where the subtropical rain belt exists. Additionally, SLD simulates the scope of the westerly jet core over East Asia more realistically than the other two dynamic cores do. Considerable systematic errors of the seasonal migration of monsoon rain belt and water vapour flux exist in all of the three versions of CAM3.1 model, although it captures the broad northward shift of convection, and the simulated results share similarities. The interannual variation of EASM is found to be more accurate in SLD simulation, which reasonably reproduces the leading combined patterns of precipitation and 850-hPa winds in East Asia, as well as the 2.5- and 10-year periods of Li-Zeng EASM index. These results emphasise the importance of dynamic cores for the EASM simulation as distinct from the simulation's sensitivity to the physical parameterisations.
Clark, Martyn P.; Serreze, Mark C.
At least four different modeling studies indicate that variability in snow cover over Asia may modulate atmospheric circulation over the North Pacific Ocean during winter. Here, satellite data on snow extent for east Asia for 1971-95 along with atmospheric fields from the National Centers for Environmental Prediction-National Center for Atmospheric Research reanalysis are used to examine whether the circulation signals seen in model results are actually observed in nature. Anomalies in snow extent over east Asia exhibit a distinct lack of persistence. This suggests that understanding the effects of east Asian snow cover is more germane for short- to medium-range weather forecasting applications than for problems on longer timescales. While it is impossible to attribute cause and effect in the empirical study, analyses of composite fields demonstrate relationships between snow cover extremes and atmospheric circulation downstream remarkably similar to those identified in model results. Positive snow cover extremes in midwinter are associated with a small decrease in air temperatures over the transient snow regions, a stronger east Asian jet, and negative geopotential height anomalies over the North Pacific Ocean. Opposing responses are observed for negative snow cover extremes. Diagnosis of storm track feedbacks shows that the action of high-frequency eddies does not reinforce circulation anomalies in positive snow cover extremes. However, in negative snow cover extremes, there are significant decreases in high-frequency eddy activity over the central North Pacific Ocean, and a corresponding decrease in the mean cyclonic effect of these eddies on the geopotential tendency, contributing to observed positive height anomalies over the North Pacific Ocean. The circulation signals over the North Pacific Ocean are much more pronounced in midwinter (January-February) than in the transitional seasons (November-December and March-April).
Yun, Kyung-Sook; Lee, June-Yi; Ha, Kyung-Ja
Observed analysis of the 35 years of 1979-2013 reveals considerable interdecadal change and significant recent intensification in the difference of convective precipitation between the South Asian monsoon (SAM) and East Asian monsoon (EAM) systems during the major summer monsoon season (June-July). We propose that the recent strengthening of the zonal gradient of sea surface temperature (SST) between the Indian Ocean, western Pacific, and eastern Pacific is a possible cause for the intensification of the convective precipitation contrast. It is noted that the strengthening of the zonal SST gradient associated with the recent mega-La Niña trend tends to reinforce the negative connection between SAM and EAM systems by inducing enhanced convection over the maritime continent and then facilitating the northwestward emanation of Rossby waves. Consequently, a cyclonic circulation anomaly that effectively changes the local Hadley circulation has been formed over the SAM region, resulting in the noticeable difference between the SAM and EAM. The years 2013 and 1983 are further investigated as the strongest extreme years for positive and negative phases of submonsoon contrast, respectively. The result confirms that the meridional dipole height pattern along the Asian Jet stream, which is caused by the strong zonal gradient of tropical SST, serves as a key trigger in strengthening the submonsoon contrast.
Lee, Seung Yong; You, Seung Hyun; Kim, Na Rae
Background Thin hairs are critical to achieve natural result in female hairline correction surgery. However, there are few studies on the usefulness of hair thinning by intense pulsed light (IPL) after hairline correction surgery in East Asian females. Methods Hair thinning using IPL was performed in 54 women who had complained about thick hairs along the frontal hairline after hairline correction surgery. Patient mean age was 31.2 years old and patients were an average of 2.1 years post-hairline correction surgery. Initial treatment used 10 J, while second and third sessions were conducted with 10 to 15 J according to responsiveness to treatment. Results Mean thickness of individual hairs assessed before the procedure was 78.86 µm. The mean number of procedures was 1.6 per patient. Forty of 54 subjects (74%) achieved satisfactory hair thinning with only one procedure from 78.01 to 66.14 µm after treatment. The measured thickness was 66.43 µm at the end of the first year in patients who were satisfied after one procedure. Thirteen cases achieved satisfactory hair thinning after two sessions. Mean thickness was 74.44 µm and 67.51 µm, before and after the second session. One case required a third session with 15J, thinning from 89.00 to 66.50 µm. Conclusions Hair thinning by IPL is a very useful method to provide a natural look after hairline correction surgery in East Asians, who have naturally thick hair. PMID:28352605
Zhang, Zhenqing; Xing, Wei; Wang, Guoping; Tong, Shouzheng; Lv, Xianguo; Sun, Jimin
Studying the peatlands accumulation and carbon (C) storage in monsoonal areas could provide useful insights into the response of C dynamics to climate variation in the geological past. Here, we integrated 40 well-dated peat/lake sediment cores to reveal the peatlands evolution history in the Sanjiang Plain and examine its links to East Asian monsoon variations during the Holocene. The results show that 80% peatlands in the Sanjiang Plain initiated after 4.7 ka (1 ka = 1000 cal yr BP), with the largest initiating frequency around 4.5 ka. The mean C accumulation rate of peatlands in the Sanjiang Plain exhibits a synchronous increase with the peatlands expansion during the Holocene. Such a peatlands expanding and C accumulating pattern corresponds well to the remarkable drying event subsequent to the Holocene monsoon maximum. We suggest that in addition to the locally topographic conditions, Holocene variations of East Asian summer monsoon (especially its associated precipitation) have played a critical role in driving the peatlands initiation and expansion in the Sanjiang Plain.
Wyrwoll, Karl-Heinz; Wei, Junhong; Lin, Zhaohui; Shao, Yaping; He, Feng
The Chinese loess/palaeosol succession is one of the most comprehensive and intensively studied archives of Neogene and Quaternary global palaeoclimate events. Its stratigraphic details are widely recognised to indicate close links to the history and function of the East Asian Winter Monsoon (EAWM) - one of the most active components of the Earth's climate system. But the formal meteorological links between the EAWM and dust emission, both in the present day and in the past, have not been established and with it, the veracity of the loess record as an indicator of the EAWM questioned. Here we show that present day major dust events over northern China, while largely occurring during spring, are nevertheless 'conditioned' by the strength of the preceding EAWM. We also demonstrate, for the first time, a close link between the occurrence of dust events and the strength of the EAWM. From these findings, linked to global-scale climate model simulations, we conclude that the Chinese loess succession provides a convincing proxy record of the strength of the East Asian Winter Monsoon.
He, Lei; Luo, Hesheng
Purpose The aldehyde dehydrogenase 2 (ALDH2) gene has been implicated in the development of alcoholic liver cirrhosis (ALC) in East Asians. However, the results are inconsistent. In this study, a meta-analysis was performed to assess the associations between the ALDH2 polymorphism and the risk of ALC. Materials and Methods Relevant studies were retrieved by searching PubMed, Web of Science, CNKI, Wanfang and Veipu databases up to January 10, 2015. Pooled odds ratio (OR) and 95% confidence interval (CI) were calculated using either the fixed- or random effects model. Results A total of twelve case-control studies included 1003 cases and 2011 controls were included. Overall, the ALDH2 polymorphism was associated with a decreased risk of ALC (*1/*2 vs. *1/*1: OR=0.78, 95% CI: 0.61–0.99). However, in stratification analysis by country, we failed to detect any association among Chinese, Korean or Japanese populations. Conclusion The pooled evidence suggests that ALDH2 polymorphism may be an important protective factor for ALC in East Asians. PMID:27189280
Zhang, Wenjun; Jin, Fei-Fei; Stuecker, Malte F.; Wittenberg, Andrew T.; Timmermann, Axel; Ren, Hong-Li; Kug, Jong-Seong; Cai, Wenju; Cane, Mark
Strong El Niño events are followed by massive summer monsoon flooding over the Yangtze River basin (YRB), home to about a third of the population in China. Although the El Niño-Southern Oscillation (ENSO) provides the main source of seasonal climate predictability for many parts of the Earth, the mechanisms of its connection to the East Asian monsoon remain largely elusive. For instance, the traditional Niño3.4 ENSO index only captures precipitation anomalies over East Asia in boreal winter but not during the summer. Here we show that there exists a robust year-round and predictable relationship between ENSO and the Asian monsoon. This connection is revealed by combining equatorial (Niño3.4) and off-equatorial Pacific sea surface temperature anomalies (Niño-A index) into a new metric that captures ENSO's various aspects, such as its interaction with the annual cycle and its different flavors. This extended view of ENSO complexity improves predictability of YRB summer flooding events.
Jin, Liya; Wang, Huijun; Chen, Fahu; Jiang, Dabang
By using a 9-level global atmospheric general circulation model developed at the Institute of Atmospheric Physics (IAP9L-AGCM) under the Chinese Academy of Sciences, the authors investigated the response of the East Asian monsoon climate to changes both in orbital forcing and the snow and glaciers over the Tibetan Plateau at the mid-Holocene, about 600 calendar years before the present (6 kyr BP). With the Earth’s orbital parameters appropriate for the mid-Holocene, the IAP9L-AGCM computed warmer and wetter conditions in boreal summer than for the present day. Under the precondition of continental snow and glacier cover existing over part of the Tibetan Plateau at the mid-Holocene, the authors examined the regional climate response to the Tibetan Plateau cooling. The simulations indicated that climate changes in South Asia and parts of central Asia as well as in East Asia are sensitive to the Tibetan Plateau cooling at the mid-Holocene, showing a significant decrease in precipitation in northern India, northern China and southern Mongolia and an increase in Southeast Asia during boreal summer. The latter seems to correspond to the weakening, southeastward shift of the Asian summer monsoon system resulting from reduced heat contrast between the Eurasian continent and the Pacific and Indian Oceans when a cooling over the Tibetan Plateau was imposed. The simulation results suggest that the snow and glacier environment over the Tibetan Plateau is an important factor for mid-Holocene climate change in the areas highly influenced by the Asian monsoon.
Indiana Univ., Bloomington. East Asian Studies Center.
This document contains five middle school lesson plans that teach about East Asia, focusing on Japan, China, and Korea. Lessons deal with geography, history, cultural comparisons, and trade relations. Lesson plans include background information, materials needed, extension and enrichment ideas, a lesson script, a rubric, a list of resources, and…
Edwards, Melissa; Bigham, Abigail; Tan, Jinze; Li, Shilin; Gozdzik, Agnes; Ross, Kendra; Jin, Li; Parra, Esteban J.
The last decade has witnessed important advances in our understanding of the genetics of pigmentation in European populations, but very little is known about the genes involved in skin pigmentation variation in East Asian populations. Here, we present the results of a study evaluating the association of 10 Single Nucleotide Polymorphisms (SNPs) located within 5 pigmentation candidate genes (OCA2, DCT, ADAM17, ADAMTS20, and TYRP1) with skin pigmentation measured quantitatively in a sample of individuals of East Asian ancestry living in Canada. We show that the non-synonymous polymorphism rs1800414 (His615Arg) located within the OCA2 gene is significantly associated with skin pigmentation in this sample. We replicated this result in an independent sample of Chinese individuals of Han ancestry. This polymorphism is characterized by a derived allele that is present at a high frequency in East Asian populations, but is absent in other population groups. In both samples, individuals with the derived G allele, which codes for the amino acid arginine, show lower melanin levels than those with the ancestral A allele, which codes for the amino acid histidine. An analysis of this non-synonymous polymorphism using several programs to predict potential functional effects provides additional support for the role of this SNP in skin pigmentation variation in East Asian populations. Our results are consistent with previous research indicating that evolution to lightly-pigmented skin occurred, at least in part, independently in Europe and East Asia. PMID:20221248
Li, J.; Ding, R.; Wu, Z.; Feng, J.; Ha, K.
Interdecadal shift in the interannual relationship between the East Asian summer monsoon (EASM) and the tropical sea surface temperature (SST) anomalies (SSTA) is investigated. The result shows that a notable feature is the enhanced relationship between the previous winter El Niño-Southern Oscillation (ENSO) and the following EASM in the past 60 years, which is opposite to the weakening relationship between the Indian summer monsoon (ISM) and ENSO since 1970s. It is also found that pronounced changes in the interannual relationship between the EASM and summer SSTA over the tropical Indian Ocean (IO) happen in the late 1970s. Besides, an enhanced relationship between the previous autumn-winter SSTA over western tropical IO and the following EASM occurs in the late 1970s. The observational and numerical evidences manifest that spring North Atlantic Oscillation (NAO) may exert notable impacts on the enhancement of the EASM-ENSO relationship. Anomalous spring NAO induces a tripole SSTA pattern in North Atlantic which persists into ensuring summer. The tripole SSTA excites downstream teleconnections of a distinct Rossby wave train prevailing over the northern Eurasia and a simple Gill-Matsuno-type quadrupole response over western Pacific. The former modulates the blocking highs over the Ural Mountain and the Okhotsk Sea. The latter enhances the linkage between the western Pacific subtropical high (WPSH) and ENSO. The co-effects of the two teleconnection patterns help to strengthen (or weaken) the subtropical Meiyu-Baiu-Changma front, the primary rain-bearing system of the EASM. As such, spring NAO is tied to the strengthened connection between ENSO and the EASM. It can be seen from the correlations of the EASM index (EASMI) with the summer IO SSTA between 1953-1975 and 1978-2000 that the SSTA pattern similar to the positive Indian Ocean Dipole (IOD) shows a strongly positive correlation with the EASMI in 1953-1975, but in 1978-2000, significant negative correlation
Kong, W.; Chiang, J. C. H.
The East Asian Summer Monsoon (EASM) varies on inter-decadal to interglacial-glacial timescales. The EASM is stronger in the mid-Holocene than today, and these changes can be readily explained by orbitally-driven insolation increase during the boreal summer. However, a detailed understanding of the altered seasonal evolution of the EASM during this time is still lacking. In particular, previous work has suggested a close link between seasonal migration of the EASM and that of the mid-latitude westerlies impinging on the Tibetan Plateau. In this study, we explore, this problem in PMIP3 climate model simulations of the mid-Holocene, focusing on the role of atmospheric circulation and in particular how the westerly jet modulates the East Asia summer climate on paleoclimate timescales. Analysis of the model simulations suggests that, compared to the preindustrial simulations, the transition from Mei-Yu to deep summer rainfall occurs earlier in the mid-Holocene. This is accompanied by an earlier weakening and northward shift of westerly jet away from the Tibetan Plateau. The variation in the strength and the 3-D structure of the westerly jet in the mid-Holocene is summarized. We find that changes to the monsoonal rainfall, westerly jet and meridional circulation covary on paleoclimate timescales. Meridional wind changes in particular are tied to an altered stationary wave pattern, resembling today's the so-called 'Silk Road' teleconnection pattern, riding along the westerly jet. Diagnostic analysis also reveals changes in moist static energy and eddy energy fluxes associated with the earlier seasonal transition of the EASM. Our analyses suggest that the westerly jet is critical to the altered dynamics of the East Asian summer monsoon during the mid-Holocene.
Discusses the difficulty of teaching Asian languages, because their mindsets and writing systems are unfamiliar to English speakers. Cites further complications, such as staffing necessities, the history of these languages as a part of area studies, and the varied needs of heritage speakers among the learners. (Author/VWL)
Lee, Isadora; Lai, Selena; Francis, Gregory; Brunette, Rachel
The 1997-98 Asian financial crisis and its aftermath have brought to light a number of crucial economic lessons. This curriculum unit focuses on some of the purported causes of the crisis, the workings of the International Monetary Fund, and the general nature of economies affected by financial turmoil. Lesson 1, "A Story of Boom and Bust in…
Do, Nguyen-Van; Ingemar, Ernberg; Phi, Phan-Thi Phi; Jenny, Almqvist; Chinh, Tran-Thi; Zeng, Yixin; Hu, Lifu
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) has an instrumental role in maintaining EBV latent infection by controlling EBV episome replication and regulating viral transcription. It is a ubiquitously expressed protein during latent viral infection and in EBV-associated tumors. The EBNA1 C-terminus interacts functionally with the Qp and Cp that control viral gene expression in latency I/II and III, respectively. EBNA1 has been classified into five subtypes due to sequence variation in the DNA-interacting C-terminus. By DNA sequence analysis of its C-terminus, we detected a main sub-variant (V-val-v1) of EBNA1 with valine located in both positions 487 and 528 from matched samples including NPC biopsies and peripheral blood taken from Vietnamese (9), Chinese (12) NPC patients and healthy donors (5). In the FR-region of oriP from nine NPC biopsies from Vietnam we also frequently found substitutions, deletions and variable numbers of repeats. Using a luciferase reporter system, EBNA1 and FR both derived from Asian isolates induced higher transcriptional activity than those from B95-8 virus.
Gordon, Chris H; Stewart, Anne-Marie E; Meijaard, Erik
Correspondence regarding Wilting A, Fischer F, Bakar SA, Linsenmair KE: Clouded leopards, the secretive top-carnivore of South-East Asian rainforests: their distribution, status and conservation needs in Sabah, Malaysia. BMC Ecol 2006, 6:16. Wilting et al. have provided their response to Gordon et al., directly following the correspondence. PMID:17605794
Kristensen, Pal; Weisaeth, Lars; Heir, Trond
The authors examined predictors of complicated grief (CG) in Norwegians 2 years after bereavement in the 2004 South-East Asian tsunami. A cross-sectional postal survey retrospectively covering disaster experiences and assessing CG according to the Inventory of Complicated Grief yielded 130 respondents (35 directly disaster-exposed and 95 not…
Yang, Liu; Zhao, Junhu; Feng, Guolin
In this study, the summer rainfall patterns in the East China monsoon region during 1951-2015 were objectively classified into four typical categories: the northern China rainfall pattern (NCP), the intermediate rainfall pattern (IRP), the Yangtze River rainfall pattern (YRP), and the South China rainfall pattern (SCP). The periods of the four patterns show significant decadal characteristics. The NCP occurred mainly between the late 1950s and the early 1980s, and the IRP in the late 1950s to the early 1970s and the 2000s. The YRP occurred mainly between the 1980s and the 1990s, and the SCP between the mid-1990s and the early 21st century. The relationship between the East Asian summer monsoon index (EASM I WF) and the four rainfall patterns was comparatively analyzed. The results confirmed that the four rainfall patterns have obvious differences in the EASM. In the NCP, IRP, or SCP years, the EASM I WF primarily showed a positive phase and a strong summer monsoon; in the YRP years, the EASM I WF primarily showed a negative phase and a weak summer monsoon.
Ng, Franklin, Ed.
The articles in this anthology address the complex subject of interethnic relations and Asian American politics, transcending ideas of Asian Americans as the model minority. The articles are: (1) "Opening the American Mind and Body: The Role of Asian American Studies" (Shirley Hume); (2) "Surviving Democracy's 'Mistake":…
Zheng, Jiayu; Li, Jianping; Feng, Juan
This study demonstrates a robust relationship between the Indo-Pacific warm pool (IPWP) and North Pacific Ocean dipole (IPOD) and the East Asian summer monsoon (EASM) using observational datasets and sensitivity tests from the Community Atmosphere Model version 3.1 of the National Center for Atmospheric Research. The IPOD, which is a significant pattern of boreal summer SSTA in the Indian and Pacific oceans characterized by positive (negative) sea-surface temperature anomalies (SSTA) in the North Pacific and negative (positive) SSTA in the IPWP, appears around May, intensifies in the following months, and weakens in September. In summers with a positive IPOD phase, the western Pacific subtropical high (WPSH) weakens and shrinks with the axis of the WPSH ridge moving northwards, which favours an intensified EASM and a decrease in summer rainfall in the Yangtze River valley, and vice versa.
Eroglu, Deniz; Ozken, Ibrahim; McRobie, Fiona; Stemler, Thomas; Marwan, Norbert; Wyrwoll, Karl-Heinz; Kurths, Juergen
The East Asian-Indonesian-Australian monsoon is the predominant low latitude monsoon system, providing a major global scale heat source. Here we apply newly developed non-linear time series techniques on speleothem climate proxies, from eastern China and northwestern Australia and establish relationships between the two summer monsoon regimes over the last ˜9000 years. We identify significant variations in monsoonal activity, both dry and wet phases, at millennial to multi-centennial time scales and demonstrate for the first time the existence of a see-saw antiphase relationship between the two regional monsoon systems. Our analysis attributes this inter-hemispheric linkage to the solar variability that is effecting both monsoon systems.
Okazaki, Sumie; Saw, Anne
In response to a call to better integrate culture in community psychology (O'Donnell in American Journal of Community Psychology 37:1-7 2006), we offer a cultural-community framework to facilitate a collaborative engagement between community psychologists and ethnic minority communities, focusing on Asian American communities as illustrations. Extending Hays' (Addressing cultural complexities in practice: Assessment, diagnosis, and therapy, American Psychological Association, Washington, DC, 2008) ADDRESSING framework for considering cultural influences on a counseling relationship, the proposed framework provides a broad but systematic guidepost for considering three major cultural-ecological influences on Asian American communities: Race and Ethnicity (R), Culture (C), and Immigration and Transnational Ties (I). We provide a sequence of steps that incorporate the ADDRESSING and the RCI frameworks to facilitate the collaborative community-based research or social action.
Yong, Rita Y Y; Mustaffa, Su'Aidah B; Wasan, Pavandip S; Sheng, Liang; Marshall, Christian R; Scherer, Stephen W; Teo, Yik-Ying; Yap, Eric P H
The human amylase gene locus at chromosome 1p21.1 is structurally complex. This region contains two pancreatic amylase genes, AMY2B, AMY2A, and a salivary gene AMY1. The AMY1 gene harbors extensive copy number variation (CNV), and recent studies have implicated this variation in adaptation to starch-rich diets and in association to obesity for European and Asian populations. In this study, we showed that by combining quantitative PCR and digital PCR, coupled with careful experimental design and calibration, we can improve the resolution of genotyping CNV with high copy numbers (CNs). In two East Asian populations of Chinese and Malay ethnicity studied, we observed a unique non-normal distribution of AMY1 diploid CN genotypes with even:odd CNs ratio of 4.5 (3.3-4.7), and an association between the common AMY2A CN = 2 genotype and odd CNs of AMY1, that could be explained by the underlying haplotypic structure. In two further case-control cohorts (n = 932 and 145, for Chinese and Malays, respectively), we did not observe the previously reported association between AMY1 and obesity or body mass index. Improved methods for accurately genotyping multiallelic CNV loci and understanding the haplotype complexity at the AMY1 locus are necessary for population genetics and association studies.
Koike, M.; Asano, N.; Nakamura, H.; Sakai, S.; Nagao, T. M.; Nakajima, T. Y.
In our previous aircraft observations, the possible influence of high sea surface temperature (SST) along the Kuroshio Current on aerosol-cloud interactions over the western North Pacific was revealed. The cloud droplet number concentration (Nc) was found to increase with decreasing near-surface static stability (NSS), which was evaluated locally as the difference between the SST and surface air temperature (SAT). To explore the spatial and temporal extent to which this warm SST influence can be operative, the present study analyzed Nc values estimated from Moderate Resolution Imaging Spectroradiometer (MODIS) satellite measurements. The comparison of the local Nc values between the high and low SST - SAT days revealed a marked increase in Nc (up to a factor of 1.8) along the Kuroshio Current in the southern East China Sea, where particularly high SST - SAT values (up to 8 K) were observed in winter under monsoonal cold air outflows from the Asian Continent. This cold airflow destabilizes the atmospheric boundary layer, which leads to enhanced updraft velocities within the well-developed mixed layer and thus greater Nc. The monsoonal northwesterlies also bring a large amount of anthropogenic aerosols from the Asian continent that increase Nc in the first place. These results suggest that the same modulations of cloud microphysics can occur over other warm western boundary currents, including the Gulf Stream, under polluted cool continental airflows. Possibilities of influencing the cloud liquid water path are also discussed.
Okada, Yukinori; Sim, Xueling; Go, Min Jin; Wu, Jer-Yuarn; Gu, Dongfeng; Takeuchi, Fumihiko; Takahashi, Atsushi; Maeda, Shiro; Tsunoda, Tatsuhiko; Chen, Peng; Lim, Su-Chi; Wong, Tien-Yin; Liu, Jianjun; Young, Terri L; Aung, Tin; Seielstad, Mark; Teo, Yik-Ying; Kim, Young Jin; Lee, Jong-Young; Han, Bok-Ghee; Kang, Daehee; Chen, Chien-Hsiun; Tsai, Fuu-Jen; Chang, Li-Ching; Fann, S-J Cathy; Mei, Hao; Rao, Dabeeru C; Hixson, James E; Chen, Shufeng; Katsuya, Tomohiro; Isono, Masato; Ogihara, Toshio; Chambers, John C; Zhang, Weihua; Kooner, Jaspal S; Albrecht, Eva; Yamamoto, Kazuhiko; Kubo, Michiaki; Nakamura, Yusuke; Kamatani, Naoyuki; Kato, Norihiro; He, Jiang; Chen, Yuan-Tsong; Cho, Yoon Shin; Tai, E-Shyong; Tanaka, Toshihiro
Chronic kidney disease (CKD), impairment of kidney function, is a serious public health problem, and the assessment of genetic factors influencing kidney function has substantial clinical relevance. Here, we report a meta-analysis of genome-wide association studies for kidney function-related traits, including 71,149 east Asian individuals from 18 studies in 11 population-, hospital- or family-based cohorts, conducted as part of the Asian Genetic Epidemiology Network (AGEN). Our meta-analysis identified 17 loci newly associated with kidney function-related traits, including the concentrations of blood urea nitrogen, uric acid and serum creatinine and estimated glomerular filtration rate based on serum creatinine levels (eGFRcrea) (P < 5.0 × 10(-8)). We further examined these loci with in silico replication in individuals of European ancestry from the KidneyGen, CKDGen and GUGC consortia, including a combined total of ∼110,347 individuals. We identify pleiotropic associations among these loci with kidney function-related traits and risk of CKD. These findings provide new insights into the genetics of kidney function.
Lou, Sijia; Russell, Lynn M.; Yang, Yang; Xu, Li; Lamjiri, Maryam A.; DeFlorio, Michael J.; Miller, Arthur J.; Ghan, Steven J.; Liu, Ying; Singh, Balwinder
We use 150 year preindustrial simulations of the Community Earth System Model to quantify the impacts of the East Asian Monsoon strength on interannual variations of springtime dust concentrations over China. The simulated interannual variations in March-April-May (MAM) dust column concentrations range between 20–40% and 10–60% over eastern and western China, respectively. The dust concentrations over eastern China correlate negatively with the East Asian Monsoon (EAM) index, which represents the strength of monsoon, with a regionally averaged correlation coefficient of 0.64. Relative to the strongest EAM years, MAMdust concentrations in the weakest EAM years are higher over China, with regional relative differences of 55.6%, 29.6%, and 13.9% in the run with emissions calculated interactively and of 33.8%, 10.3%, and 8.2% over eastern, central, and western China, respectively, in the run with prescribed emissions. Both interactive run and prescribed emission run show the similar pattern of climate change between the weakest and strongest EAM years. Strong anomalous northwesterly and westerly winds over the Gobi and Taklamakan deserts during the weakest EAM years result in larger transport fluxes, and thereby increase the dust concentrations over China. These differences in dust concentrations between the weakest and strongest EAM years (weakest-strongest) lead to the change in the net radiative forcing by up to 8 and 3Wm2 at the surface, compared to 2.4 and +1.2Wm2 at the top of the atmosphere over eastern and western China, respectively.
Lin, N.; Tsay, S.; Hsu, N. C.; Holben, B. N.; Anh, N.; Reid, J. S.; Sheu, G.; Chi, K.; Wang, S.; Lee, C.; Wang, L.; Wang, J.; Chen, W.; Welton, E. J.; Liang, S.; Sopajaree, K.; Maring, H. B.; Janjai, S.; Chantara, S.
The Seven South East Asian Studies (7-SEAS) is a grass-root program and seeks to perform interdisciplinary research in the field of aerosol-meteorology and climate interaction in the Southeast Asian region, particularly for the impact of biomass burning on cloud, atmospheric radiation, hydrological cycle, and regional climate. Participating countries include Indonesia, Malaysia, Philippines, Singapore, Thailand, Taiwan, Vietnam, and USA. A series of field experiments have been conducted during springtime biomass burning seasons in northern Southeast Asia, i.e., Dongsha Experiment in 2010, Son La Campaigns in 2011 and 2012, and BASELInE (Biomass-burning Aerosols & Stratocumulus Environment: Lifecycles and Interactions Experiment) in 2013, respectively. Given an example, during 2010 Dongsha Experiment, a monitoring network for ground-based measurements was established, including five stations from northern Thailand and central Vietnam to Taiwan, with a supersite at the Dongsha Island (i.e. Pratas Island) in South China Sea (or East Sea). Aerosol chemistry sampling was performed for each station for characterizing the compositions of PM2.5/PM10 (some for TSP) including water-soluble ions, metal elements, BC/OC, Hg and dioxins. This experiment provides a relatively complete and first dataset of aerosol chemistry and physical observations conducted in the source/sink region for below marine boundary layer and lower free troposphere of biomass burning/air pollutants in the northern SE Asia. This presentation will give an overview of these 7-SEAS activities and their results, particularly for the characterization of biomass-burning aerosol at source regions in northern Thailand and northern Vietnam, and receptor stations in Taiwan, which is rarely studied.
Tong, Jieli; Xiang, Wen Wei; Ang, An Shing; Sim, Wen Jun; Quah, Kien Hong; Foo, David; Ong, Paul Jau Lueng; Ho, Hee Hwa
Objective To evaluate the clinical characteristics and in-hospital outcomes of elderly South-East Asian patients undergoing primary percutaneous coronary intervention (PPCI). Methods From January 2009 to December 2012, 1268 patients (86.4% male, mean age of 58.4 ± 12.2 years) presented to our hospital for ST-elevation myocardial infarction (STEMI) and underwent PPCI. They were divided into two groups: elderly group defined as age ≥ 70 years and non-elderly group defined as age < 70 years. Data were collected retrospectively on baseline clinical characteristics, door-to-balloon (D2B) time, angiographic findings, therapeutic modality and hospital course. Results The elderly group constituted 19% of the study population with mean age 76.6 ± 5.0 years. There was a higher proportion of female gender and ethnic Chinese patients in the elderly group when compared with the non-elderly group. The former was less likely to be smokers and have a significantly higher prevalence of hypertension. The mean D2B time was significantly longer in the elderly group. They also had a significantly higher incidence of triple vessel disease and obstructive left main disease. The use of radial artery access, glycoprotein 2b/3a inhibitors and drug-eluting stents during PPCI were also significantly lower. In-hospital mortality was significantly higher in the elderly group. The rate of cardiogenic shock and inhospital complications were also significantly higher. Conclusions Our registry showed that in-hospital mortality rate in elderly South-East Asian patients undergoing PPCI for STEMI was high. Further studies into the optimal STEMI management strategy for these elderly patients are warranted. PMID:27928224
Wang, Yongjin; Cheng, Hai; Edwards, R Lawrence; Kong, Xinggong; Shao, Xiaohua; Chen, Shitao; Wu, Jiangyin; Jiang, Xiouyang; Wang, Xianfeng; An, Zhisheng
High-resolution speleothem records from China have provided insights into the factors that control the strength of the East Asian monsoon. Our understanding of these factors remains incomplete, however, owing to gaps in the record of monsoon history over the past two interglacial-glacial cycles. In particular, missing sections have hampered our ability to test ideas about orbital-scale controls on the monsoon, the causes of millennial-scale events and relationships between changes in the monsoon and climate in other regions. Here we present an absolute-dated oxygen isotope record from Sanbao cave, central China, that completes a Chinese-cave-based record of the strength of the East Asian monsoon that covers the past 224,000 years. The record is dominated by 23,000-year-long cycles that are synchronous within dating errors with summer insolation at 65 degrees N (ref. 10), supporting the idea that tropical/subtropical monsoons respond dominantly and directly to changes in Northern Hemisphere summer insolation on orbital timescales. The cycles are punctuated by millennial-scale strong-summer-monsoon events (Chinese interstadials), and the new record allows us to identify the complete series of these events over the past two interglacial-glacial cycles. Their duration decreases and their frequency increases during glacial build-up in both the last and penultimate glacial periods, indicating that ice sheet size affects their character and pacing. The ages of the events are exceptionally well constrained and may thus serve as benchmarks for correlating and calibrating climate records.
Zheng, Xufeng; Li, Anchun; Wan, Shiming; Kao, Shuhji; Kuhn, Gerhard
Deep-sea fan sediments provide an excellent geological archive for paleoenvironment reconstruction. Grain size, clay mineral and elemental (Ti, Fe, Ca) compositions were measured for a core retrieved from a submarine fan in the Okinawa Trough. Varimax-rotated Principal Component Analysis (V-PCA) on time-evolution of grain size spectrum reveals that, since the Holocene, sediment was transported mainly by the benthic nepheloid layer (33%) and upper layers (33%) which is driven by the East Asian winter monsoon (EAWM). The intensification of the Kuroshio Current during the Holocene, masks the fluvial signal of the summer monsoon and obstructs clay minerals derived from the Yellow River, a major contributor prior to 12 ka BP. A new grain size index (GSI), which represents the EAWM well, exhibits a negative correlation with the δ18O record in Dongge Cave, China during the Holocene when sea level was relatively steady. This anticorrelation suggests the southward migration of the Intertropical Convergence Zone (ITCZ). The consistency among our records and rainfall records in Peru, Ti counts in the Cariaco Basin, monsoon records in Oman and the averaged summer insolation pattern at 30°N further support the ITCZ's impact on monsoon systems globally. Cross-Correlation Analyses for GSI and log(Ti/Ca) against δ18O record in Dongge Cave reveal a decoupling between the East Asian winter and summer monsoon during 5500-2500 cal yr BP, with greater complexity in the last 2500 years. This can be attributed to exacerbated ENSO mode fluctuations and possibly anthropogenic interference superimposed on insolation and ITCZ forcing.
Kim, Judy Joo-Hyun
This study explored the effectiveness of an instructional tool, elaborate analogy, in teaching the particle theory to both Grade 7 mainstream and East or South Asian ESL students. Ten Grade 7 science classes from five different schools in a large school district in the Greater Toronto area participated. Each of the ten classes were designated as either Group X or Y. Using a quasi-experimental counterbalanced design, Group X students were taught one science unit using the elaborate analogies, while Group Y students were taught by their teachers' usual methods of teaching. The instructional methods used for Group X and Y were interchanged for the subsequent science unit. Quantitative data were collected from 95 students (50 mainstream and 45 ESL) by means of a posttest and a follow-up test for each of the units. When the differences between mainstream and East or South Asian ESL students were analyzed, the results indicate that both groups scored higher on the posttests when they were instructed with elaborate analogies, and that the difference between the two groups was not significant. That is, the ESL students, as well as the mainstream students, benefited academically when they were instructed with the elaborate analogies. The students obtained higher inferential scores on the posttest when their teacher connected the features of less familiar and more abstract scientific concepts to the features of the familiar and easy-to-visualize concept of school dances. However, after two months, the students were unable to recall inferential content knowledge. This is perhaps due to the lack of opportunity for the students to represent and test their initial mental models. Rather than merely employing elaborate analogies, perhaps, science teachers can supplement the use of elaborate analogies with explicit guidance in helping students to represent and test the coherence of their mental models.
Yonekura, Emmi; Hall, Timothy M.
Improvements on a statistical tropical cyclone (TC) track model in the western North Pacific Ocean are described. The goal of the model is to study the effect of El Nino-Southern Oscillation (ENSO) on East Asian TC landfall. The model is based on the International Best-Track Archive for Climate Stewardship (IBTrACS) database of TC observations for 1945-2007 and employs local regression of TC formation rates and track increments on the Nino-3.4 index and seasonally varying climate parameters. The main improvements are the inclusion of ENSO dependence in the track propagation and accounting for seasonality in both genesis and tracks. A comparison of simulations of the 1945-2007 period with observations concludes that the model updates improve the skill of this model in simulating TCs. Changes in TC genesis and tracks are analyzed separately and cumulatively in simulations of stationary extreme ENSO states. ENSO effects on regional (100-km scale) landfall are attributed to changes in genesis and tracks. The effect of ENSO on genesis is predominantly a shift in genesis location from the southeast in El Nino years to the northwest in La Nina years, resulting in higher landfall rates for the East Asian coast during La Nina. The effect of ENSO on track propagation varies seasonally and spatially. In the peak activity season (July-October), there are significant changes in mean tracks with ENSO. Landfall-rate changes from genesis- and track-ENSO effects in the Philippines cancel out, while coastal segments of Vietnam, China, the Korean Peninsula, and Japan show enhanced La Nina-year increases.
Ma, Hongyun; Jiang, Zhihong; Song, Jie; Dai, Aiguo; Yang, Xiuqun; Huo, Fei
The effects of urban land-use change in East China on the East Asian summer monsoon (EASM) are investigated using a Community Atmosphere Model Version 5.1. The results show that the urban land-use change in East China causes spatially-varying changes in surface net radiation and heat fluxes, atmospheric circulation, and water budgets. It results in significant surface warming (cooling) and precipitation decrease (increase) in a large region north (south) of 30°N. Urban expansion agglomerated in (29°-41°N, 110°-122°E) alters the surface energy budget and warms the surface, resulting in strengthened southwesterly airflow south of 25°N and increased convergence below the mid-troposphere between 20° and 30°N. A concomitant northward downdraft associated with the increased convection generates an anomalous high pressure north of 30°N. Meanwhile, the downdraft not only produces adiabatic warming but also inhibits the dynamic condition for precipitation formation. The anomalous high pressure formed in North China prevents the southwesterly airflow from advancing northward, leading to increase the convergence and precipitation in South China. These changes reduce the meridional temperature gradient in the mid-lower troposphere and weaken the westerly airflow near 30°N. In addition, horizontal transport of vorticity north of 35°N weakens significantly, which leads to an anomalous barotropic structure of anticyclonic there. As a result, the anomalous anticyclonic circulation and descent north of 30°N are strengthened. At the same time, the anomalous cyclonic circulation and ascent south of 30°N are enhanced. These process induced by the thermal state changes due to urbanization weakens the EASM.
Koh, Xuan-Han; Liu, Xuanyao; Teo, Yik-Ying
Body fat deposition and distribution differ between East Asians and Europeans, and for the same level of obesity, East Asians are at higher risks of Type 2 diabetes (T2D) and other metabolic disorders. This observation has prompted the reclassifications of body mass index thresholds for the definitions of “overweight” and “obese” in East Asians. However, the question remains over what evolutionary mechanisms have driven the differences in adiposity morphology between two population groups that shared a common ancestor less than 80,000 years ago. The Thrifty Gene hypothesis has been suggested as a possible explanation, where genetic factors that allowed for efficient food-energy conversion and storage are evolutionarily favoured by conferring increased chances of survival and fertility. Here, we leveraged on the existing findings from genome-wide association studies and large-scale surveys of positive natural selection to evaluate whether there is currently any evidence to support the Thrifty Gene hypothesis. We first assess whether the existing genetic associations with obesity and T2D are located in genomic regions that are reported to be under positive selection, and if so, whether the risk alleles sit on the extended haplotype forms. In addition, we interrogate whether these risk alleles are the derived forms that differ from the ancestral alleles, and whether there is significant evidence of population differentiation at these SNPs between East Asian and European populations. Our systematic survey did not yield conclusive evidence to support the Thrifty Gene hypothesis as a possible explanation for the differences observed between East Asians and Europeans. PMID:25337808
Takekawa, J.Y.; Newman, S.H.; Xiao, X.; Prosser, D.J.; Spragens, K.A.; Palm, E.C.; Yan, B.; Li, T.; Lei, F.; Zhao, D.; Douglas, D.C.; Muzaffar, S.B.; Ji, W.
Poyang Lake is situated within the East Asian Flyway, a migratory corridor for waterfowl that also encompasses Guangdong Province, China, the epicenter of highly pathogenic avian influenza (HPAI) H5N1. The lake is the largest freshwater body in China and a significant congregation site for waterfowl; however, surrounding rice fields and poultry grazing have created an overlap with wild waterbirds, a situation conducive to avian influenza transmission. Reports of HPAI H5N1 in healthy wild ducks at Poyang Lake have raised concerns about the potential of resilient free-ranging birds to disseminate the virus. Yet the role wild ducks play in connecting regions of HPAI H5N1 outbreak in Asia is hindered by a lack of information about their migratory ecology. During 2007-08 we marked wild ducks at Poyang Lake with satellite transmitters to examine the location and timing of spring migration and identify any spatiotemporal relationship with HPAI H5N1 outbreaks. Species included the Eurasian wigeon (Anas penelope), northern pintail (Anas acuta), common teal (Anas crecca), falcated teal (Anas falcata), Baikal teal (Anas formosa), mallard (Anas platyrhynchos), garganey (Anas querquedula), and Chinese spotbill (Anas poecilohyncha). These wild ducks (excluding the resident mallard and Chinese spotbill ducks) followed the East Asian Flyway along the coast to breeding areas in northern China, eastern Mongolia, and eastern Russia. None migrated west toward Qinghai Lake (site of the largest wild bird epizootic), thus failing to demonstrate any migratory connection to the Central Asian Flyway. A newly developed Brownian bridge spatial analysis indicated that HPAI H5N1 outbreaks reported in the flyway were related to latitude and poultry density but not to the core migration corridor or to wetland habitats. Also, we found a temporal mismatch between timing of outbreaks and wild duck movements. These analyses depend on complete or representative reporting of outbreaks, but by
Siska, Veronika; Jones, Eppie Ruth; Jeon, Sungwon; Bhak, Youngjune; Kim, Hak-Min; Cho, Yun Sung; Kim, Hyunho; Lee, Kyusang; Veselovskaya, Elizaveta; Balueva, Tatiana; Gallego-Llorente, Marcos; Hofreiter, Michael; Bradley, Daniel G; Eriksson, Anders; Pinhasi, Ron; Bhak, Jong; Manica, Andrea
Ancient genomes have revolutionized our understanding of Holocene prehistory and, particularly, the Neolithic transition in western Eurasia. In contrast, East Asia has so far received little attention, despite representing a core region at which the Neolithic transition took place independently ~3 millennia after its onset in the Near East. We report genome-wide data from two hunter-gatherers from Devil's Gate, an early Neolithic cave site (dated to ~7.7 thousand years ago) located in East Asia, on the border between Russia and Korea. Both of these individuals are genetically most similar to geographically close modern populations from the Amur Basin, all speaking Tungusic languages, and, in particular, to the Ulchi. The similarity to nearby modern populations and the low levels of additional genetic material in the Ulchi imply a high level of genetic continuity in this region during the Holocene, a pattern that markedly contrasts with that reported for Europe.
Siska, Veronika; Jones, Eppie Ruth; Jeon, Sungwon; Bhak, Youngjune; Kim, Hak-Min; Cho, Yun Sung; Kim, Hyunho; Lee, Kyusang; Veselovskaya, Elizaveta; Balueva, Tatiana; Gallego-Llorente, Marcos; Hofreiter, Michael; Bradley, Daniel G.; Eriksson, Anders; Pinhasi, Ron; Bhak, Jong; Manica, Andrea
Ancient genomes have revolutionized our understanding of Holocene prehistory and, particularly, the Neolithic transition in western Eurasia. In contrast, East Asia has so far received little attention, despite representing a core region at which the Neolithic transition took place independently ~3 millennia after its onset in the Near East. We report genome-wide data from two hunter-gatherers from Devil’s Gate, an early Neolithic cave site (dated to ~7.7 thousand years ago) located in East Asia, on the border between Russia and Korea. Both of these individuals are genetically most similar to geographically close modern populations from the Amur Basin, all speaking Tungusic languages, and, in particular, to the Ulchi. The similarity to nearby modern populations and the low levels of additional genetic material in the Ulchi imply a high level of genetic continuity in this region during the Holocene, a pattern that markedly contrasts with that reported for Europe. PMID:28164156
van Donkelaar, A.; Martin, R. V.; Leaitch, W. R.; MacDonald, A. M.; Walker, T. W.; Streets, D. G.; Zhang, Q.; Dunlea, E. J.; Jimenez, J. L.; Dibb, J. E.; Huey, L. G.; Weber, R.; Andreae, M. O.
We interpret a suite of satellite, aircraft, and ground-based measurements over the North Pacific Ocean and western North America during April-May 2006 as part of the Intercontinental Chemical Transport Experiment Phase B (INTEX-B) campaign to understand the implications of long-range transport of East Asian emissions to North America. The Canadian component of INTEX-B included 33 vertical profiles from a Cessna 207 aircraft equipped with an aerosol mass spectrometer. Long-range transport of organic aerosols was insignificant, contrary to expectations. Measured sulfate plumes in the free troposphere over British Columbia exceeded 2 μg/m3. We update the global anthropogenic emission inventory in a chemical transport model (GEOS-Chem) and use it to interpret the observations. Aerosol Optical Depth (AOD) retrieved from two satellite instruments (MISR and MODIS) for 2000-2006 are analyzed with GEOS-Chem to estimate an annual growth in Chinese sulfur emissions of 6.2% and 9.6%, respectively. Analysis of aircraft sulfate measurements from the NASA DC-8 over the central Pacific, the NSF C-130 over the east Pacific and the Cessna over British Columbia indicates most Asian sulfate over the ocean is in the lower free troposphere (800-600 hPa), with a decrease in pressure toward land due to orographic effects. We calculate that 56% of the measured sulfate between 500-900 hPa over British Columbia is due to East Asian sources. We find evidence of a 72-85% increase in the relative contribution of East Asian sulfate to the total burden in spring off the northwest coast of the United States since 1985. Campaign-average simulations indicate anthropogenic East Asian sulfur emissions increase mean springtime sulfate in Western Canada at the surface by 0.31 μg/m3 (~30%) and account for 50% of the overall regional sulfate burden between 1 and 5 km. Mean measured daily surface sulfate concentrations taken in the Vancouver area increase by 0.32 μg/m3 per 10% increase in the simulated
van Donkelaar, A.; Martin, R. V.; Leaitch, W. R.; MacDonald, A. M.; Walker, T. W.; Streets, D. G.; Zang, Q.; Dunlea, E.; Jimenez, J. L.; Dibb, J. E.; Huley, G.; Weber, R.; Andreae, M. O.
We interpret a suite of satellite, aircraft, and ground-based measurements over the North Pacific Ocean and western North America during April-May 2006 as part of the Intercontinental Chemical Transport Experiment Phase B (INTEX-B) campaign to understand the implications of long-range transport of East Asian emissions to North America. The Canadian component of INTEX-B included 33 vertical profiles from a Cessna 207 aircraft equipped with an aerosol mass spectrometer. Long-range transport of organic aerosols was insignificant. Measured sulfate plumes in the free troposphere over British Columbia exceeded 1 μg/m3. We update the global anthropogenic emission inventory in a chemical transport model (GEOS-Chem) and use it to interpret the observations. Trends in Aerosol Optical Depth (AOD) retrieved from two satellite instruments (MISR and MODIS) for 2000-2006 are analyzed with GEOS-Chem to estimate an annual growth in Chinese sulfur emissions of 6.2% and 9.6%, respectively. Analysis of aircraft sulfate measurements from the NASA DC-8 over the central Pacific, the NSF C-130 over the east Pacific and the Cessna over British Columbia indicates most Asian sulfate over the ocean is in the lower free troposphere (800-600 hPa), with a decrease in pressure toward land due to orographic effects. We calculate that 63% of the measured sulfate at 600 hPa over British Columbia is due to East Asian sources. Simulation of INTEX-B and May 1985 aircraft measurements off the northwest coast of the United States reveals a 2.4-3.4 fold increase in the relative contribution of East Asian sulfate to the total burden. Campaign-average simulations indicate anthropogenic East Asian sulfur emissions increase mean springtime sulfate in Western Canada at the surface by 0.14-0.19 μg/m3 (~30%) and account for 40% of the overall regional sulfate burden between 1 and 5 km. Mean measured daily surface sulfate concentrations taken in the Vancouver area increase by 0.27 μg/m3 per 10% increase in the
Finlayson, Jill; Ghassemifar, Reza; Holmes, Paula; Grey, Dianne; Figliomeni, Lisa; Newbound, Christopher; Pell, Nicole; Kersten, Michael; Jennens, Michelle; Macaulay, Claire; Greenwood, Laura; Beilby, John
Routine hemoglobin (Hb) analyses identified a new β-globin variant in a family from East Timor. The red cell indices were within normal limits for all affected family members. The variant is due to a missense mutation at amino acid codon 80 (AAC>CAC) which results in the substitution of histidine for asparagine.
Ke, Y; Su, B; Xiao, J; Chen, H; Huang, W; Chen, Z; Chu, J; Tan, J; Jin, L; Lu, D
We investigated the distribution of Y-chromosome haplotype using 19 Y-SNPs in Han Chinese populations from 22 provinces of China. Our data indicate distinctive patterns of Y chromosome between southern and northern Han Chinese populations. The southern populations are much more polymorphic than northern populations. The latter has only a subset of the southern haplotypes. This result confirms the genetic difference observed between southern and northern ethnic populations in East Asia. It supports the hypothesis that the first settlement of modern humans of African origin occurred in the southern part of East Asia during the last Ice Age, and a northward migration led to the peopling of northern China.
Meta-analyses of European populations has successfully identified genetic variants in over 100 loci associated with lipid levels, but our knowledge in other ethnicities remains limited. To address this, we performed dense genotyping of circa 2,000 candidate genes in 7,657 African Americans, 1,315 Hi...
Dong, Hao; Campbell, Cameron; Kurosu, Satomi; Lee, James Z.
In the past, many people were ‘unfree’ in the sense that their movement was restricted, and out-migration without permission was regarded and recorded as ‘escape.’ Even though such escape was common in the past, historical studies mostly neglect this form of migration. This paper examines escape in historical East Asia, focusing on the influence of household context and individual characteristics on the chances of escape, taking advantage of large-scale individual panel datasets from three adjacent unfree populations from northeast China, southeast Korea and northeast Japan in the 18th and 19th century. We not only find similar temporal, spatial, and age patterns of escape, but also similar patterns of associations between chances of escape and household context. In particular, the presence of dependent children and elderly in the household makes individuals less likely to escape. Other patterns of association also highlight the importance of gender and social class. Despite significant differences in political, social, and community context across these three East Asian populations, our empirical comparisons suggest important commonalities in terms of motivation driven by shared understandings of obligation to others. PMID:26989495
Ikehara, K.; Usami, K.
The late Quaternary sediments of the Japan Sea is characterized by the alternation of dark and light colored layers. Temporal occurrence of the dark layers has similar pattern with the Dansgaard-Oeschger cycle in the Greenland ice cores. It is considered that the dark layers were formed under the high primary productivity conditions related to enhanced inflow of nutrient-rich East China Sea surface water. We analyzed the sediment color with 0.2 mm intervals of a core collected from the central Japan Sea, and planktonic/benthic foraminiferal assemblages of another core from the southern Japan Sea. The results indicate the clear difference between the dark layers of MIS5 and of MIS 3-4. Higher productivity was expected for the former period but due to the relatively higher ventilation (lateral supply) of dissolved oxygen during the period, the dark layer formation occurred under the delicate balance between the oxygen consumption and supply. On the other hand, during MIS3-4, dark layer had sharp base and finely laminated, and low oxygen tolerant benthic foraminifera was dominant in the dark layer. This suggests that the dark layer formation was mainly controlled by not degradation at the sediment surface but the development of low-oxygen bottom water. The difference of the mechanism of dark layer formation was controlled by the global eustatic sea level changes and the East Asian summer monsoon fluctuation related to the mid-latitude insolation.
Schlager, H.; Arnold, F.; Aufmhoff, H.; Baumann, R.; Pirjola, L.; Roiger, A.; Sailer, T.; Wirth, M.; Schumann, U.
We report on a case study of anthropogenic SO2 pollution transport into the lower stratosphere from East Asian source regions. The pollution layer was observed over Central Europe by measurements from the new German research aircraft HALO. The layer contained enhanced SO2, HNO3 and water vapor and caused increased Lidar backscatter radiation. Meteorological analysis and air mass transport and dispersion model simulations reveal that the detected pollutants were released from ground-based sources in East-China, South-Korea, and Japan. The pollution plume was uplifted by a warm conveyor belt associated with a West-Pacific cyclone and finally injected into the lower stratosphere. Our HALO measurements were performed 5 days after the air mass uplift event, when significant parts of the Northern Hemisphere were already covered by the pollution plume. Accompanying trajectory chemistry and aerosol box model simulations indicate that H2SO4/H2O aerosol droplets were generated in the SO2-rich plume and grew to sizes large enough to explain the observed increased Lidar backscatter signal. Implications of the SO2 transport pathway into the lower stratosphere presented in this study will be discussed.
Xie, Xiaoning; Wang, Hongli; Liu, Xiaodong; Li, Jiandong; Wang, Zhaosheng; Liu, Yangang
Because industrial emissions of anthropogenic aerosols over East Asia have greatly increased in recent decades, the interactions between atmospheric aerosols and the East Asian summer monsoon (EASM) have attracted enormous attention. To further understand the aerosol-EASM interaction, we investigate the impacts of anthropogenic aerosols on the EASM during the multidecadal strong (1950-1977) and weak (1978-2000) EASM stages using the Community Atmospheric Model 5.1. Numerical experiments are conducted for the whole period, including the two different EASM stages, with present day (PD, year 2000) and preindustrial (PI, year 1850) aerosol emissions, as well as the observed time-varying aerosol emissions. A comparison of the results from PD and PI shows that, with the increase in anthropogenic aerosols, the large-scale EASM intensity is weakened to a greater degree (-9.8%) during the weak EASM stage compared with the strong EASM stage (-4.4%). The increased anthropogenic aerosols also result in a significant reduction in precipitation over North China during the weak EASM stage, as opposed to a statistically insignificant change during the strong EASM stage. Because of greater aerosol loading and the larger sensitivity of the climate system during weak EASM stages, the aerosol effects are more significant during these EASM stages. These results suggest that anthropogenic aerosols from the same aerosol emissions have distinct effects on the EASM and the associated precipitation between the multidecadal weak and strong EASM stages.
Xie, Xiaoning; Wang, Hongli; Liu, Xiaodong; Li, Jiandong; Wang, Zhaosheng; Liu, Yangang
Industrial emissions of anthropogenic aerosols over East Asia have greatly increased in recent decades, and so the interactions between atmospheric aerosols and the East Asian summer monsoon (EASM) have attracted enormous attention. In order to further understand the aerosol-EASM interaction, we investigate the impacts of anthropogenic aerosols on the EASM during the multidecadal strong (1950–1977) and weak (1978–2000) EASM stages using the Community Atmospheric Model 5.1. Numerical experiments are conducted for the whole period, including the two different EASM stages, with present day (PD, year 2000) and preindustrial (PI, year 1850) aerosol emissions, as well as the observed time-varying aerosol emissions. A comparison of the results from PD and PI shows that, with the increase in anthropogenic aerosols, the large-scale EASM intensity is weakened to a greater degree (-9.8%) during the weak EASM stage compared with the strong EASM stage (-4.4%). The increased anthropogenic aerosols also result in a significant reduction in precipitation over North China during the weak EASM stage, as opposed to a statistically insignificant change during the strong EASM stage. Because of greater aerosol loading and the larger sensitivity of the climate system during weak EASM stages, the aerosol effects are more significant during these EASM stages. Moreover, these results suggest that anthropogenic aerosols from the same aerosol emissions have distinct effects on the EASM and the associated precipitation between the multidecadal weak and strong EASM stages.
Xie, Xiaoning; Wang, Hongli; Liu, Xiaodong; ...
Industrial emissions of anthropogenic aerosols over East Asia have greatly increased in recent decades, and so the interactions between atmospheric aerosols and the East Asian summer monsoon (EASM) have attracted enormous attention. In order to further understand the aerosol-EASM interaction, we investigate the impacts of anthropogenic aerosols on the EASM during the multidecadal strong (1950–1977) and weak (1978–2000) EASM stages using the Community Atmospheric Model 5.1. Numerical experiments are conducted for the whole period, including the two different EASM stages, with present day (PD, year 2000) and preindustrial (PI, year 1850) aerosol emissions, as well as the observed time-varying aerosolmore » emissions. A comparison of the results from PD and PI shows that, with the increase in anthropogenic aerosols, the large-scale EASM intensity is weakened to a greater degree (-9.8%) during the weak EASM stage compared with the strong EASM stage (-4.4%). The increased anthropogenic aerosols also result in a significant reduction in precipitation over North China during the weak EASM stage, as opposed to a statistically insignificant change during the strong EASM stage. Because of greater aerosol loading and the larger sensitivity of the climate system during weak EASM stages, the aerosol effects are more significant during these EASM stages. Moreover, these results suggest that anthropogenic aerosols from the same aerosol emissions have distinct effects on the EASM and the associated precipitation between the multidecadal weak and strong EASM stages.« less
Han, J.; Shin, B.; Lee, M.; Hwang, G.; Kim, J.; Shim, J.; Lee, G.; Shim, C.
Ieodo Ocean Research Station (IORS), a research tower (~ 40 m a.s.l.) for atmospheric and oceanographic observations, is located in the East China Sea (32.07° N, 125.10° E). The IORS is almost equidistant from South Korea, China, and Japan and, therefore, it is an ideal place to observe Asian outflows without local emission effects. The average ozone concentrations were 51.8 ± 15.9 ppbv during June 2003-December 2010. The seasonal variation of ozone was distinct, with a summer minimum (37.8 ppbv) and a spring maximum (61.1 ppbv), and was largely affected by seasonal wind pattern over East Asia. The fractional contribution of ozone at IORS could be attributed to six well distinguished air masses that were classified by the cluster analysis of backward trajectories. Marine air from the Pacific Ocean represents a relatively clean background air with a lowest ozone level of 32.2 ppbv in summer. In spring and winter the influence of Chinese outflows was dominant with higher ozone concentrations of 61.6 and 49.3 ppbv, respectively. This study confirms that the influence of Chinese outflows was the main factor determining O3 levels at IORS, of which extent was apt to be changed by meteorological state, particularly at a long-term scale.
Han, J.; Shin, B.; Lee, M.; Hwang, G.; Kim, J.; Shim, J.; Lee, G.; Shim, C.
Ieodo Ocean Research Station (IORS), a research tower (~ 40 m a.s.l.) for atmospheric and oceanographic observations, is located in the East China Sea (32.07° N, 125.10° E). The IORS is almost equidistant from South Korea, China, and Japan and, therefore, it is an ideal place to observe Asian outflows without local emission effects. The seasonal variation of ozone was distinct, with a minimum in August (37 ppbv) and two peaks in April and October (62 ppbv), and was largely affected by the seasonal wind pattern over east Asia. At IORS, six types of air masses were distinguished with different levels of O3 concentrations by the cluster analysis of backward trajectories. Marine air masses from the Pacific Ocean represent a relatively clean background air with a lowest ozone level of 32 ppbv, which was most frequently observed in summer (July-August). In spring (March-April) and winter (December-February), the influence of Chinese outflows was dominant with higher ozone concentrations of 62 and 49 ppbv, respectively. This study confirms that the influence of Chinese outflows was the main factor determining O3 levels at IORS and its extent was dependent on meteorological state, particularly at a long-term scale.
Foo, Jia Nee; Tan, Louis C; Irwan, Ishak D; Au, Wing-Lok; Low, Hui Qi; Prakash, Kumar-M; Ahmad-Annuar, Azlina; Bei, Jinxin; Chan, Anne Yy; Chen, Chiung Mei; Chen, Yi-Chun; Chung, Sun Ju; Deng, Hao; Lim, Shen-Yang; Mok, Vincent; Pang, Hao; Pei, Zhong; Peng, Rong; Shang, Hui-Fang; Song, Kyuyoung; Tan, Ai Huey; Wu, Yih-Ru; Aung, Tin; Cheng, Ching-Yu; Chew, Fook Tim; Chew, Soo-Hong; Chong, Siow-Ann; Ebstein, Richard P; Lee, Jimmy; Saw, Seang-Mei; Seow, Adeline; Subramaniam, Mythily; Tai, E-Shyong; Vithana, Eranga N; Wong, Tien-Yin; Heng, Khai Koon; Meah, Wee-Yang; Khor, Chiea Chuen; Liu, Hong; Zhang, Furen; Liu, Jianjun; Tan, Eng-King
Genome-wide association studies (GWAS) on Parkinson's disease (PD) have mostly been done in Europeans and Japanese. No study has been done in Han Chinese, which make up nearly a fifth of the world population. We conducted the first Han Chinese GWAS analysing a total of 22,729 subjects (5,125 PD cases and 17,604 controls) from Singapore, Hong Kong, Malaysia, Korea, mainland China and Taiwan. We performed imputation, merging and logistic regression analyses of 2,402,394 SNPs passing quality control filters in 779 PD cases, 13,227 controls, adjusted for the first three principal components. 90 SNPs with association P < 10-4 were validated in 9 additional sample collections and the results were combined using fixed-effects inverse-variance meta-analysis. We observed strong associations reaching genome-wide significance at SNCA, LRRK2 and MCCC1, confirming their important roles in both European and Asian PD. We also identified significant (P < 0.05) associations at 5 loci (DLG2, SIPA1L2, STK39, VPS13C and RIT2), and observed the same direction of associations at 9 other loci including BST1 and PARK16. Allelic heterogeneity was observed at LRRK2 while European risk SNPs at 6 other loci including MAPT and GBA-SYT11 were non-polymorphic or very rare in our cohort. Overall, we replicate associations at SNCA, LRRK2, MCCC1 and 14 other European PD loci but did not identify Asian-specific loci with large effects (OR > 1.45) on PD risk. Our results also demonstrate some differences in the genetic contribution to PD between Europeans and Asians. Further pan-ethnic meta-analysis with European GWAS cohorts may unravel new PD loci.
Czehut, Katherine Jessica Drake
International mathematics assessments have established students in East Asia as among the best in the world and their U.S. counterparts as mediocre. What is not clear is why this "achievement gap" exists. The last major study to address this question, Stevenson and Stigler's (1992) "The Learning Gap," was published prior to…
Christianity as a world religion was propagated from Europe and North America to Africa and Asia. Global Christianity spread to East Asia when Robert Morrison (1782-1843) arrived in Canton, China in 1807, and later in the late 19th-century Protestant missionaries from North America arrived in Japan and Korea. This Christianity experienced a modern…
Hao, Zhixin; Sun, Di; Zheng, Jingyun
Based on observational data and Asian monsoon intensity datasets from China, the relationships between the East Asian winter monsoon index and winter temperature, the East Asian summer monsoon index and Meiyu precipitation over the middle and lower reaches of the Yangtze River, were analyzed. We found that the monsoon signals were reflected in the temperature and Meiyu precipitation variations. Thus, we used the reconstructed Meiyu precipitation and winter temperature series for the past 300 years and detected the summer/winter monsoon intensity signals using multi-taper spectral estimation method and wavelet analysis. The main periodicities of Meiyu precipitation and winter temperature, such as interannual cycle with 2-7-year, interdecadal-centennial cycles with 30-40-year and 50-100-year, were found. The good relationships between the East Asian summer and winter monsoons suggested that they were in phase at 31-year cycle, while out of phase at 100-year cycle, but with 20-year phase difference. In addition, the winter monsoon intensity may be regulated by the North Atlantic Oscillation, the Arctic Oscillation and the Atlantic Multidecadal Oscillation, and the summer monsoon is closely related to the signal intensities of the Pacific Decadal Oscillation.
Hao, Zhixin; Sun, Di; Zheng, Jingyun
Based on observational data and Asian monsoon intensity datasets from China, the relationships between the East Asian winter monsoon index and winter temperature, the East Asian summer monsoon index and Meiyu precipitation over the middle and lower reaches of the Yangtze River, were analyzed. We found that the monsoon signals were reflected in the temperature and Meiyu precipitation variations. Thus, we used the reconstructed Meiyu precipitation and winter temperature series for the past 300 years and detected the summer/winter monsoon intensity signals using multi-taper spectral estimation method and wavelet analysis. The main periodicities of Meiyu precipitation and winter temperature, such as interannual cycle with 2–7-year, interdecadal-centennial cycles with 30–40-year and 50–100-year, were found. The good relationships between the East Asian summer and winter monsoons suggested that they were in phase at 31-year cycle, while out of phase at 100-year cycle, but with 20-year phase difference. In addition, the winter monsoon intensity may be regulated by the North Atlantic Oscillation, the Arctic Oscillation and the Atlantic Multidecadal Oscillation, and the summer monsoon is closely related to the signal intensities of the Pacific Decadal Oscillation. PMID:26107375
Wen, Z.; Guo, Y.
The leading mode of boreal winter precipitation variability over the tropical Pacific for the period 1980-2010 shows a west-east dipole pattern with one center over the western North Pacific (WNP) and Maritime Continent and the other center over the equatorial central Pacific (CP). Observational evidences show that the variability of the East Asian upper-tropospheric subtropical westerly jet (EAJ) has a significant correlation with precipitation anomalies over the WNP and CP and that tropical precipitation anomalies over WNP and CP have distinct influence on the variation of EAJ. A series of numerical experiments based on a linear baroclinic model are performed to confirm the influence of the heating anomalies associated with precipitation perturbations over the WNP and CP on the EAJ. The results of numerical experiments indicate that a heat source over the WNP can excite a northward-propagating Rossby wave train in the upper troposphere over East Asia and facilitate a poleward eddy momentum flux. It results in the acceleration of westerly between 30°N and 45°N, which favors a northward displacement of the EAJ. The response induced by a heat sink over the CP features a zonal easterly band between 25°N and 40°N, suggesting that the response to heat sink associated with negative precipitation anomalies over the CP may weaken the EAJ. A strengthened relationship was found between tropical Pacific precipitation and EAJ since 1979. The modeling results suggest that the shift of mean states might be responsible for the strengthened EAJ-rainfall relationship after 1979.
Yin, Guohua; Bennett, Joan Wennstrom
Medicinal fungi, taken whole or as various forms of extracts, have been used to alleviate, cure or prevent human ailments since pre-historic times. In particular, Asian cultures have incorporated a variety of mushrooms into their medical practices. Chemically pure, bioactive metabolites from fungi have been a mainstay of modern pharmacological research and in addition to antibiotics, include anticancer agents, immunosuppressants, enzyme inhibitors, antagonist and agonists of hormones, and a variety of psychotropic substances. However, to date not many studies have focused on the possible health benefits of odorant volatile organic compounds (i.e., gas phase compounds). An analysis of these compounds for their health related effects will expand the range of compounds available for the treatment of chronic and acute diseases. This review highlights phenolic acids and monoterpenes from Asian medicinal mushrooms (AMMs), which not only produce pleasant odors but also have antioxidant and antibacterial effects. Odorant bioactive volatile phase compounds from medicinal mushrooms remain an essentially untapped source for future medicines, and AMMs remain a promising resource for future pharmacological research. PMID:25892909
Niccoli, Sarah; Abraham, Suraj; Richard, Christina; Zehbe, Ingeborg
We examined how well the human papillomavirus (HPV) E6 oncogene can function in the absence of the E7 oncogene during the carcinogenic process in human keratinocytes using a common HPV variant strongly associated with cervical cancer: the Asian-American E6 variant (AAE6). This E6 variant is 20 times more frequently detected in cervical cancer than the prototype European E6 variant, as evidenced by independent epidemiological data. Using cell culture and cell-based functional assays, we assessed how this variant can perform crucial carcinogenesis steps compared to the prototype E6 variant. The ability to immortalize and transform primary human foreskin keratinocytes (PHFKs) to acquire resilient phenotypes and the ability to promote cell migration were evaluated. The immortalization capability was assayed based on population doublings, number of passages, surpassing mortality stages 1 and 2, human telomerase reverse transcriptase (hTERT) expression, and the ability to overcome G(1) arrest via p53 degradation. Transformation and migration efficiency were analyzed using a combination of functional cell-based assays. We observed that either AAE6 or prototype E6 proteins alone were sufficient to immortalize PHFKs, although AAE6 was more potent in doing so. The AAE6 variant protein alone pushed PHFKs through transformation and significantly increased their migration ability over that of the E6 prototype. Our findings are in line with epidemiological data that the AA variant of HPV16 confers an increased risk over the European prototype for cervical cancer, as evidenced by a superior immortalization, transformation, and metastatic potential.
Xiao, Chuliang; Zhang, Yaocun; Lofgren, Brent M.; Nie, Yu
The variability of East Asian upper level westerly jets in winter is studied with regard to the concurrent existence of subtropical jet (East Asian subtropical jet (EASJ)) and polar-front jet (East Asian polar-front jet (EAPJ)) using the National Centers for Environmental Prediction/National Center for Atmospheric Research reanalysis. In the distribution of jet occurrence revealed in 6-hourly data, two jet branches along 30°N and 55°N, corresponding to locations of EASJ and EAPJ, respectively, are separated over the Tibetan Plateau. The leading two modes of zonal-mean zonal wind in East Asia extracted from a mass-weighted empirical orthogonal function analysis are characterized by the intensity changes and location displacements of two jets. The key regions for EASJ and EAPJ are then defined to represent variabilities of these two jets. Correlation analysis indicates that the subseasonal variation of EAPJ precedes EASJ by around 5 days, which can be interpreted as wave-mean flow interactions via synoptic-scale transient eddy activities. Based on the pentad intensity indices of two jets, the concurrent variabilities of EASJ and EAPJ are investigated with typical temperature and precipitation anomalies in China. The results suggest that by taking account of the two jets, we are able to get a more comprehensive understanding of the winter climate.
Wang, Dongdong; Zhu, Bin; Jiang, Zhihong; Yang, Xiu-Qun; Zhu, Tong
Aerosol emissions have rapidly increased in East Asia since the late 1970s. During the same period, the East Asian summer monsoon has shown a weakening trend. In this work, the direct effects (DE) of sulfate and black carbon (BC) aerosols on the subseasonal (pentad mean) march of the East Asian subtropical summer monsoon (EASSM) are investigated using an interactive global climate-chemistry model. The simulation results suggest that the DE of sulfate aerosols have a notable effect on the cooling of the low troposphere across the continent in spring and autumn, hence, changing the time of the seasonal transition of the zonal land-sea thermal contrast (ZTC). The DE of BC result in cooling of the low troposphere and heating of the middle troposphere, leading to a different impact than that caused by sulfates. The cooling of the surface and troposphere by sulfates leads to a delay in the warming of East Asian continent in spring and the EASSM onset time; it also accelerates the process of the continent turning colder and advances the retreat of the EASSM. The deeper heating in the middle-upper troposphere than the cooling in the low troposphere due to the DE of BC or the combination of both lead to an advance in the onset time of the monsoon caused by the continent turning warmer earlier in spring. In autumn, the same cooling effect by sulfates leads to the continent turning colder earlier, resulting in an advance in the retreat time.
The author reviews the literature on the trends and characteristics of international migration within and from East and Southeast Asia, with a focus on the past 25 years. "Five migration systems are described: settler, student, contract labor, skilled labor, and refugee. Settler migration to the U.S., Canada and Australia has consisted primarily of family members.... Contract labor migration, particularly to the Middle East, has provided jobs, foreign currency through remittances and greater participation of women, but also led to illegal migration, skills drain, and labor abuses. The hierarchy of development has led to intra-regional flows: (1) skilled labor mainly from Japan to other countries in the region, and (2) contract labor and illegal migration from the LDCs to the NIEs [newly industrializing economies] and Japan."
Chiam, Chun Wei; Chan, Yoke Fun; Ong, Kien Chai; Wong, Kum Thong; Sam, I-Ching
Chikungunya virus (CHIKV), an alphavirus of the family Togaviridae, causes fever, polyarthritis and rash. There are three genotypes: West African, Asian and East/Central/South African (ECSA). The latter two genotypes have caused global outbreaks in recent years. Recent ECSA CHIKV outbreaks have been associated with severe neurological disease, but it is not known if different CHIKV genotypes are associated with different neurovirulence. In this study, the neurovirulence of Asian (MY/06/37348) and ECSA (MY/08/065) strains of CHIKV isolated in Malaysia were compared. Intracerebral inoculation of either virus into suckling mice was followed by virus titration, histopathology and gene expression analysis of the harvested brains. Both strains of CHIKV replicated similarly, yet mice infected with MY/06/37348 showed higher mortality. Histopathology findings showed that both CHIKV strains spread within the brain (where CHIKV antigen was localized to astrocytes and neurons) and beyond to skeletal muscle. In MY/06/37348-infected mice, apoptosis, which is associated with neurovirulence in alphaviruses, was observed earlier in brains. Comparison of gene expression showed that a pro-apoptotic gene (eIF2αK2) was upregulated at higher levels in MY/06/37348-infected mice, while genes involved in anti-apoptosis (BIRC3), antiviral responses and central nervous system protection (including CD40, IL-10RA, MyD88 and PYCARD) were upregulated more highly in MY/08/065-infected mice. In conclusion, the higher mortality observed following MY/06/37348 infection in mice is due not to higher viral replication in the brain, but to differentially expressed genes involved in host immune responses. These findings may help to identify therapeutic strategies and biomarkers for neurological CHIKV infections.
Asian butch-dykes have been overlooked in analyses of Chinese cinema, studies that often concentrate on "feminized" transgender roles. This article examines cinematic representations of Asian butch-dykes through film analysis of Enter the Mullet (2004), a five-minute short, and in-depth interviews with the filmmaker, Donna Lee, a Chinese-Canadian in Vancouver. Lee's film is inspired by Enter the Dragon (1973), starring Bruce Lee, the most recognized icon of Asian masculinity. Combining with the mullet hairstyle, which is often associated with White working-class, the filmmaker introduces viewers to the hybrid masculinity of Asian butch-dykes. The article argues that Asian female masculinity can be a strategic means of destabilizing the hegemony of White-male-middle-class masculinity.
Shao, X.; Huang, L.; Yin, Z.; Guo, Q.
East Asian monsoon is crucial for modulating the climate in China. Especially, the summer monsoon is closely related to the severe flood and drought events in eastern China. To study the characteristics of summer monsoon a long-term record is needed. In this study we attempted to examine the interdecadal variations of East Asian monsoon by using tree-ring data. The summer monsoon index (Ism) for the period of 1873- 2000 was calculated using sea level pressure data. Firstly, we calculated the difference (ΔP) of the sea level pressure between the land (110ºE) and sea (160ºE) from 10ºN to 50ºN with 5º intervals. Then the ΔP values that are smaller than or equal to -5 hPa in June, July and August were summed and defined as the Ism. By this definition Ism values greater than 1.0 represent strong monsoon conditions, and vice versa. Sea level pressure data prior to 1951 were obtained from the Meteorological Office of United Kingdom, and that afterwards were from the NCEP data set. The tree ring data of Qilian junipers (Sabina przewalskii Kom.) are from the northeastern part of the Qaidam Basin, located along the northeastern margin of the Qinghai-Tibetan Plateau. These tree-ring data have been used to reconstruct local precipitation and soil moisture conditions. Previous studies have revealed that there was a teleconnection in rainfall between eastern China and the Qinghai-Tibetan Plateau. We examined the relationships of the ring-width series with the Ism series over the common period of 1873-2000 AD. We found that the tree-ring widths were statistical significantly correlated with Ism. These negative correlations increased significantly after a low-pass filter was used for both data sets, indicating very good potential for reconstruction of low-frequency variations of Ism in the past. Variability of the Ism series and ring-width series were examined using power spectrum analysis and wavelet transformation. The reconstructed Ism values during the period 1440
Logan, Shanna; Steel, Zachary; Hunt, Caroline
Previous research has demonstrated the importance of intercultural willingness to interact; however, these investigations have yet to be applied to a health context or to compare an ethnic minority with a majority sample. Consequently, the current study sought to better understand engagement with health services by investigating both attitudes towards seeking psychological help and intercultural willingness to interact within an ethnic minority South East Asian population, relative to an Anglo Australian sample. As predicted, negative attitudes towards seeking psychological help were higher in the South East Asian sample, with this relationship persisting across generations, despite significant differences in acculturation. In contrast, intercultural willingness to interact was not associated with ethnicity status but was associated with higher anxiety, uncertainty, ethnocentrism and help-seeking, consistent with current empirical and theoretical literature. The current study also sought to examine factors associated with help-seeking attitudes and found that ethnocentrism was a significant predictor, when accounting for previous health experience.
Li, Jing; Carlson, Barbara E.; Lacis, Andrew A.
Spectral dependence of aerosol single-scattering albedo (SSA) has been used to infer aerosol composition. In particular, aerosol mixtures dominated by dust absorption will have monotonically increasing SSA with wavelength while that dominated by black carbon absorption has monotonically decreasing SSA spectra. However, by analyzing SSA measured at four wavelengths, 440, 675, 870, and 1020 nm from the Aerosol Robotic Network data set, we find that the SSA spectra over East Asia are frequently peaked at 675 nm. In these cases, we suggest that SSA spectral curvature, defined as the negative of the second derivative of SSA as a function of wavelength, can provide additional information on the composition of these aerosol mixtures. Aerosol SSA spectral curvatures for East Asia during fall and winter are considerably larger than those found in places primarily dominated by biomass burning or dust aerosols. SSA curvature is found to increase as the SSA magnitude decreases. The curvature increases with coarse mode fraction (CMF) to a CMF value of about 0.4, then slightly decreases or remains constant at larger CMF. Mie calculations further verify that the strongest SSA curvature occurs at approx. 40% dust fraction, with 10% scattering aerosol fraction. The nonmonotonic SSA spectral dependence is likely associated with enhanced absorption in the shortwave by dust, absorption by black carbon at longer wavelengths, and also the flattened absorption optical depth spectral dependence due to the increased particle size.
Kim, J.; Li, S.; Muhle, J.; Fang, X.; Manning, A. J.; Arnold, T.; Park, S.; Park, M.; Saito, T.; Yokouchi, Y.; Stohl, A.; Weiss, R. F.; Kim, K.
Tetrafluoromethane (CF4) and Hexafluoroethane (C2F6) are among the most potent greenhouse gases (GHGs), with atmospheric lifetimes of 50,000 and 10,000 years and 100-year Global Warming Potentials of 7,490 and 12,200, respectively. The Chinese aluminum smelting (AL) industry, accounting for 39% of the global aluminum production in 2010, has become a significant emitter of these compounds to the atmosphere, . The AL industry has estimated its Chinese emissions averaged over 2008-2010 at 1.4 Gg/yr of CF4 and 0.06 Gg/yr of C2F6. In this study we combine East Asian measurements of C2F6 at Gosan (Jeju Island, Korea), Hateruma, and Ochi-Ishi (Japan) and of CF4 at Gosan, using inversion techniques and two Lagrangian particle dispersion models (FLEXPART and NAME), to estimate the emissions of these two compounds from China and East Asia. Our results yield total emissions from China for the 2008-2010 period of approximately 4 × 0.5 Gg/yr for CF4 and 0.8 × 0.1 Gg/yr for C2F6. These results may be reconciled if emissions of these compounds from China's semiconductor (SC) industry are larger than currently estimated. However, evidence presented in the analysis of the inversion results and in the C2F6/CF4 emission ratios observed for China suggest that China's AL industry emissions are likely to be the dominant source of the discrepancy between reported emissions and those inferred from atmospheric measurements. As the AL and SC industries evolve toward new manufacturing technologies that reduce GHG emissions, continued and improved atmospheric measurements and modeling in this region will be useful in assessing the effectiveness of these changes.
Yamada, K.; Sakai, S.; Seto, K.
Oxygen isotope ratios of ostracode shells (δ18Oostracode) from the central part of Lake Nakaumi, southwest Japan were examined to clarify intensity of East Asian summer monsoon (EASM) in the last 1700 years. Adult whole shell of Bicornucythere bisanensis, which grow into adulthood from April to August in the present Nakaumi, was used for δ18O measurements. Long-term trend in δ18Oostracode correspond with salinity changes in Lake Nakaumi caused by regional geographic events based on analysis of fossil ostracode assemblages. Five short-term increases in δ18Oostracode were recognized in 500, 900, 1350, 1650 and 1850 AD, which correspond with weak periods of the EASM intensity based on δ18O of stalagmite in Wanxiang cave. Intensity of EASM is representative of precipitation around the Japan. For recent ostracodes, δ18Oostracode positively correlated with bottom water salinity, which related negatively to precipitation and positively to δ18O of lake water in the recent Nakaumi. Thus, it might be interpreted that the short-term fluctuations in δ18Oostracode were caused by intensity change of EASM, since δ18Oostracode will increase due to low precipitation during weak periods of EASM. Further, the compiled data demonstrate that at least five EASM weakening periods, in 500, 900, 1350, 1650 and 1850 AD, occurred between 30° and 40° N in East Asia in the last 1700 years. These timings accord with data from sites, which suggests that oscillations of the EASM have been synchronous across the region.
Chakrabarty, R. K.; Beres, N. D.; Moosmuller, H.; Bender, F.; Ramanathan, V.
Light absorption due to aerosols in the atmosphere is dominated by black carbon (BC) particles emitted from combustion sources. BC particles in the atmosphere have been observed to exist as sub-micron sized fractal-like aggregates, and several studies have been conducted to characterize BC fractal morphologies and their influence on radiative forcing. In this study, we report our observation of BC "superaggregates" (SAs) in the long-range transport of pollutants during the 2012 CARDEX (Cloud, Aerosol, and Radiative forcing Dynamics EXperiment) campaign based on the island of Hanimaadhoo in the Republic of Maldives. Scanning electron microscopy (SEM) images reveal occurrence of SAs in abundance on the filter substrates. These particles have a mean mobility diameter of ~3μm and a fractal dimension (Df¬) of ~2.64 - consistent with the prediction by gelation/percolation theory of aggregation. Back-trajectory analysis indicates that these SAs originated from Southeast Asian biomass burning episodes during February 27 - March 01, 2012. The knowledge of SA physical characteristics makes it possible to estimate their optical properties and contribution to short-wave radiative forcing.ypical Superaggregates of Black Carbon Observed during CARDEX
Weng, H.-Y.; Lau, K.-M.
One of the main factors that might have caused the disastrous flood in China during 1998 summer is long-term variations that include a trend indicating increasing monsoon rainfall over the Yangtze River Valley. China's 160-station monthly rainfall anomaly for the summers of 1955-98 is analyzed for exploring such long-term variations. Singular value decomposition (SVD) between the summer rainfall and the global sea surface temperature (SST) anomalies reveals that the rainfall over Yangtze River Valley is closely related to global and regional SST variabilities at both interannual and interdecadal timescales. SVD1 mode links the above normal rainfall condition in central China to an El Nino-like SSTA distribution, varying on interannual timescale modified by a trend during the period. SVD3 mode links positive rainfall anomaly in Yangtze River Valley to the warm SST anomaly in the subtropical western Pacific, varying on interannual timescales modified by interdecadal timescales. This link tends to be stronger when the Nino3 area becomes colder and the western subtropical Pacific becomes warmer. The 1998 summer is a transition season when the 1997/98 El Nino event was in its decaying phase, and the SST in the Nino3 area emerged below normal anomaly while the subtropical western Pacific SST above normal. Thus, the first and third SVD modes become dominant in 1998 summer, favoring more Asian summer monsoon rainfall over the Yangtze River Valley.
Identifying, Instructing and Rehabilitating South East Asian Students with Special Needs and Counseling Their Parents. Report of a Meeting Held at the Annual Conference of the National Association for South East Asian Students with Special Needs (San Francisco, California, March 13, 1985) and a Workshop (June 9-12, 1985).
Dao, Mai; Grossman, Herbert
The report provides background information on the educational needs of disabled South East Asian students and presents four papers from a meeting and workshop on the topic held respectively in March and June of 1985. A draft of an action plan advocated by meeting participants addresses ways to meet five major needs: (1) to obtain information on…
Sultana, H.; Seo, D. W.; Bhuiyan, M. S. A.; Choi, N. R.; Hoque, M. R.; Heo, K. N.; Lee, J. H.
The maternally inherited mitochondrial DNA (mtDNA) D–loop region is widely used for exploring genetic relationships and for investigating the origin of various animal species. Currently, domestic ducks play an important role in animal protein supply. In this study, partial mtDNA D–loop sequences were obtained from 145 samples belonging to six South-East Asian duck populations and commercial duck population. All these populations were closely related to the mallard duck (Anas platyrhynchos), as indicated by their mean overall genetic distance. Sixteen nucleotide substitutions were identified in sequence analyses allowing the distinction of 28 haplotypes. Around 42.76% of the duck sequences were classified as Hap_02, which completely matched with Anas platyrhynchos duck species. The neighbor-joining phylogenetic tree also revealed that South-East Asian duck populations were closely related to Anas platyrhynchos. Network profiles were also traced using the 28 haplotypes. Overall, results showed that those duck populations D-loop haplotypes were shared between several duck breeds from Korea and Bangladesh sub continental regions. Therefore, these results confirmed that South-East Asian domestic duck populations have been domesticated from Anas platyrhynchos duck as the maternal origins. PMID:27004808
Chang, C.; Shen, C.; Chiang, H.; Chen, Y.; Lam, D.; Ngai, N.
The climate in the South China Sea (SCS), a semi-closed ocean basin with a narrow opening in the north to the Western Pacific Ocean, is mainly constrained by the East Asian summer and winter monsoons. Due to the limited instrumental data, the quantitative evaluation of both influences on local and regional areas is still beyond the capacity of climate models. The geochemical proxy records in coral skeletons provide a potential way to retrieve the history of hydrological and climatic conditions with weekly to monthly resolution. We present geochemical proxy records in a 12-year modern Porites coral collected from Son Tra Island, central Vietnam in June, 2005. Three features are exhibited as follows. (1) The winter data of coral δ18O match well with the instrumental SST observations. This consistency indicates that the winter coral δ18O can reflect the regional hydrological conditions, which is dominated by the East Asian winter monsoon. (2) The variation of interannual summer coral δ18O values differ from that of instrumental SST record. The episodic enriched coral δ18O in summer might reflect sea surface water cooling events, triggered by enhancement of the East Asian summer monsoon (EASM) and/or local salinity increase. (3) The diachronous characteristics of seasonal and interannual trends among different elements, such as Al, Ba, Fe and Cd, shows the dynamic natural of EASM-induced seasonal upwelling and the variability of terrestrial sediment transport over the past 12 years in this area.
Woo, Jane S T; Morshedian, Negar; Brotto, Lori A; Gorzalka, Boris B
Research has examined the relationship between religiosity and sexuality but few studies have explored the mechanisms by which sexual variables are influenced by religiosity. The purpose of the present study was to investigate the role of sex guilt in the relationship between religiosity and sexual desire in women. Euro-Canadian (n = 178) and East Asian (n = 361) female university students completed a battery of questionnaires. Higher levels of religious fundamentalism, intrinsic religiosity and spirituality were associated with higher levels of sex guilt in both ethnic groups. Paranormal belief was not associated with sex guilt in either ethnic group. The Euro-Canadian women reported significantly higher levels of sexual desire and significantly less sex guilt than the East Asian women. Among the Euro-Canadian women, sex guilt mediated the relationships between spirituality and sexual desire, and fundamentalism and sexual desire; among the East Asian women, sex guilt mediated the relationships between spirituality and sexual desire, fundamentalism and sexual desire, and intrinsic religiosity and sexual desire. These findings suggest that sex guilt may be one mechanism by which religiosity affects sexual desire among women.
Kang, Jung-Yoon; Tanaka, Taichu Y.; Mikami, Masao; Yoon, Soon-Chang
There are few dust simulation studies for East Asian dust events that took place in the wintertime, when the surface conditions of the dust source region differ from those of the springtime. The soil water turns into ice when the temperature falls below freezing, and the ice might prohibit wind erosion by increasing the binding strength between soil particles. However, the contribution of frozen soil to reducing dust outbreaks remains unclear. This study investigates the effect of frozen soil on dust emission through a case study of a severe wintertime East Asian dust event that originated on 23 and 24 December 2009 in Southern Mongolia and Inner Mongolia and reached Korea on 25 and 26 December 2009 using WRF/Chem with a new dust emission scheme. Model simulations with and without the effect of frozen soil were conducted. A temperature below 0°C and relative soil saturation exceeding 40% were used for frozen soil criteria, and the frozen soil was prohibited from emitting dust. The dust concentrations derived from the simulation without the effect of frozen soil were about three times higher than the observed PM10 concentrations, while the results from the simulation with the frozen-soil effect were quite similar to those of the observation data. The simulation of the wintertime East Asian dust event with the frozen-soil effect improved the model representation. The sensitivity tests for frozen soil indicate that the criteria of frozen soil used in this study are appropriate for this case study.
Jin, Liya; Zhang, Xiaojian; Leduc, Guillaume
Rashid et al. (2016) questioned the use of the Mg-/Ca-based sea surface temperature (SST) data from the subpolar North Atlantic Ocean as well as the alkenone-based SST data from the western tropical Indian Ocean we used to reflect the winter SSTs or regional changes in the Holocene SSTs. We first would like to reemphasize that the main message we wanted to convey in our article is that the East Asian winter monsoon (EAWM) strength decreased and then increased again during the Holocene but with a substantial lag in southern China as compared to northern China. We, of course, wanted to back up our model results with published SST data that may have detected such an asynchronous variation in the EAWM. For convenience, we used a series of proxy records extracted from the extended Global database for alkenone-derived HOlocene Sea-surface Temperature (GHOST) database that were initially intended to provide a template of Holocene SST trends for model/data comparison purpose (http://doi.pangaea.de/10.1594/PANGAEA.737370). Rashid et al. (2016) questioned our model/data comparison exercise, arguing that the data we present in Zhang et al. (2015a) cannot be used to track leads and lags in winter SSTs in the North Atlantic and northern Indian Ocean. Below we address point by point the issues raised by Rashid et al. (2016) and thank the authors for giving us the opportunity to sharpen our model/data comparison analysis.
Lin, Renping; Zhu, Jiang; Zheng, Fei
The East Asian summer monsoon (EASM) experienced decadal transitions over the past few decades, and the associated "wetter-South-drier-North" shifts in rainfall patterns in China significantly affected the social and economic development in China. Two viewpoints stand out to explain these decadal shifts, regarding the shifts either a result of internal variability of climate system or that of external forcings (e.g. greenhouse gases (GHGs) and anthropogenic aerosols). However, most climate models, for example, the Atmospheric Model Intercomparison Project (AMIP)-type simulations and the Coupled Model Intercomparison Project (CMIP)-type simulations, fail to simulate the variation patterns, leaving the mechanisms responsible for these shifts still open to dispute. In this study, we conducted a successful simulation of these decadal transitions in a coupled model where we applied ocean data assimilation in the model free of explicit aerosols and GHGs forcing. The associated decadal shifts of the three-dimensional spatial structure in the 1990s, including the eastward retreat, the northward shift of the western Pacific subtropical high (WPSH), and the south-cool-north-warm pattern of the upper-level tropospheric temperature, were all well captured. Our simulation supports the argument that the variations of the oceanic fields are the dominant factor responsible for the EASM decadal transitions. PMID:27934933
Su, Tao; Liu, Yu-Sheng (Christopher); Jacques, Frédéric M. B.; Huang, Yong-Jiang; Xing, Yao-Wu; Zhou, Zhe-Kun
Climate change during the Quaternary played an important role in the distribution of extant plants. Herein, cone scales of Cedrus (Pinaceae) were uncovered from the Upper Pliocene Sanying Formation, Longmen Village, Yongping County of Yunnan Province in southwestern China. Detailed comparisons show that these fossils all belong to the genus Cedrus (Pinaceae), and a new species is proposed, Cedrus angusta sp. nov. This find expands the known distribution of Cedrus during the Late Pliocene to Yunnan, where the genus no longer exists in natural forests. Based on the analysis of reconstructed Neogene climate data, we suggest that the intensification of the East Asian winter monsoon during the Quaternary may have dramatically increased seasonality and given rise to a much drier winter in Yunnan. Combined with information on Cedrus fossil records and its seed physiology, we conclude that the intensification of a drier climate after the Late Pliocene may have prevented the survival of Cedrus seedlings, leading to the eventual disappearance of Cedrus in western Yunnan. This study indicates that the topography in southwestern China acted as a vital refuge for many plants during the Quaternary, but that other species gradually disappeared due to the intensification of the monsoonal climate.
Jiang, Tianyu NMI; Evans, Katherine J; Deng, Yi; Dong, Xiquan
In this study, an atmospheric river (AR) detection algorithm is developed to investigate the downstream modulation of the eastern North Pacific ARs by another weather extreme, known as the East Asian cold surge (EACS), in both reanalysis data and high-resolution global model simulations. It is shown that following the peak of an EACS, atmospheric disturbances of intermediate frequency (IF; 10 30 day period) are excited downstream. This leads to the formation of a persistent cyclonic circulation anomaly over the eastern North Pacific that dramatically enhances the AR occurrence probability and the surface precipitation over the western U.S. between 30 N and 50 N. A diagnosis of the local geopotential height tendency further confirms the essential role of IF disturbances in establishing the observed persistent anomaly. This downstream modulation effect is then examined in the two simulations of the National Center for Atmospheric Research Community Climate System Model version 4 with different horizontal resolutions (T85 and T341) for the same period (1979 2005). The connection between EACS and AR is much better captured by the T341 version of the model, mainly due to a better representation of the scale interaction and the characteristics of IF atmospheric disturbances in the higher-resolution model. The findings here suggest that faithful representations of scale interaction in a global model are critical for modeling and predicting the occurrences of hydrological extremes in the western U.S. and for understanding their potential future changes.
Zhang, Ben; Jia, Wei-Hua; Matsuda, Koichi; Kweon, Sun-Seog; Matsuo, Keitaro; Xiang, Yong-Bing; Shin, Aesun; Jee, Sun Ha; Kim, Dong-Hyun; Cai, Qiuyin; Long, Jirong; Shi, Jiajun; Wen, Wanqing; Yang, Gong; Zhang, Yanfeng; Li, Chun; Li, Bingshan; Guo, Yan; Ren, Zefang; Ji, Bu-Tian; Pan, Zhi-Zhong; Takahashi, Atsushi; Shin, Min-Ho; Matsuda, Fumihiko; Gao, Yu-Tang; Oh, Jae Hwan; Kim, Soriul; Ahn, Yoon-Ok; Chan, Andrew T; Chang-Claude, Jenny; Slattery, Martha L.; Gruber, Stephen B.; Schumacher, Fredrick R.; Stenzel, Stephanie L.; Casey, Graham; Kim, Hyeong-Rok; Jeong, Jin-Young; Park, Ji Won; Li, Hong-Lan; Hosono, Satoyo; Cho, Sang-Hee; Kubo, Michiaki; Shu, Xiao-Ou; Zeng, Yi-Xin; Zheng, Wei
Known genetic loci explain only a small proportion of the familial relative risk of colorectal cancer (CRC). We conducted the largest genome-wide association study in East Asians with 14,963 CRC cases and 31,945 controls and identified six new loci associated with CRC risk (P = 3.42 × 10−8 to 9.22 × 10−21) at 10q22.3, 10q25.2, 11q12.2, 12p13.31, 17p13.3 and 19q13.2. Two of these loci map to genes (TCF7L2 and TGFB1) with established roles in colorectal tumorigenesis. Four other loci are located in or near genes involved in transcription regulation (ZMIZ1), genome maintenance (FEN1), fatty acid metabolism (FADS1 and FADS2), cancer cell motility and metastasis (CD9) and cell growth and differentiation (NXN). We also found suggestive evidence for three additional loci associated with CRC risk near genome-wide significance at 8q24.11, 10q21.1 and 10q24.2. Furthermore, we replicated 22 previously reported CRC loci. Our study provides insights into the genetic basis of CRC and suggests new biological pathways. PMID:24836286
Lin, Renping; Zhu, Jiang; Zheng, Fei
The East Asian summer monsoon (EASM) experienced decadal transitions over the past few decades, and the associated "wetter-South-drier-North" shifts in rainfall patterns in China significantly affected the social and economic development in China. Two viewpoints stand out to explain these decadal shifts, regarding the shifts either a result of internal variability of climate system or that of external forcings (e.g. greenhouse gases (GHGs) and anthropogenic aerosols). However, most climate models, for example, the Atmospheric Model Intercomparison Project (AMIP)-type simulations and the Coupled Model Intercomparison Project (CMIP)-type simulations, fail to simulate the variation patterns, leaving the mechanisms responsible for these shifts still open to dispute. In this study, we conducted a successful simulation of these decadal transitions in a coupled model where we applied ocean data assimilation in the model free of explicit aerosols and GHGs forcing. The associated decadal shifts of the three-dimensional spatial structure in the 1990s, including the eastward retreat, the northward shift of the western Pacific subtropical high (WPSH), and the south-cool-north-warm pattern of the upper-level tropospheric temperature, were all well captured. Our simulation supports the argument that the variations of the oceanic fields are the dominant factor responsible for the EASM decadal transitions.
Lee, Seung Hyoun; Lee, Yong Il; Yoon, Ho Il; Yoo, Kyu-Cheul
A 4.96-m-long sediment core from the Hanon paleo-maar in Jeju Island, Korea was studied to investigate the paleoclimatic change and East Asian monsoon variations during the latest Pleistocene to early Holocene (23,000-9000 cal yr BP). High-resolution TOC content, magnetic susceptibility, and major element composition data indicate that Jeju Island experienced the coldest climate around 18,000 cal yr BP, which corresponds to the last glacial maximum (LGM). Further, these multi-proxy data show an abrupt shift in climatic regime from cold and arid to warm and humid conditions at around 14,000 cal yr BP, which represents the commencement of the last major deglaciation. After the last major deglaciation, the TOC content decreased from 13,300 to 12,000 cal yr BP and from 11,500 to 9800 cal yr BP, thereby reflecting the weakening of the summer monsoon. The LGM in Jeju Island occurred later in comparison with the Chinese Loess Plateau. Such a disparity in climatic change events between central China and Jeju Island appears to be caused by the asynchrony between the coldest temperature event and the minimum precipitation event in central China and by the buffering effect of the Pacific Ocean.
Gong, Zhiqiang; Li, Shangfeng; Hu, Po; Shen, Baizhu; Feng, Guolin
This paper systematically evaluates the deviations that appear in the hindcasts of the East Asian summer precipitation (EASP) decadal change in the late 1990s in two global coupled models (BCC_CGCM and BCC_CSM). The possible causes for the deviations between the model hindcasts and observations are analyzed. The results show that the hindcasts of EASP by BCC_CGCM and BCC_CSM deviate from observations, with the anomaly correlation coefficient (ACC) being -0.01 and -0.09 for the two models, respectively. The SST anomalies in North and West Pacific and the SST index values predicted by the two models also deviate from the observations, indicating that inconsistent SST fields may be the key factor leading to the deviation in the prediction of the EASP decadal shift. Thus, a dynamic-analogue scheme is proposed to correct the precipitation hindcasts by using SSTs, where SST and EASP are highly correlated, to select historical analogue cases. Cross validations show that the average ACC of the temporal-latitude distribution of the EASP between the corrected hindcasts and observations is 0.18 for BCC_CGCM and 0.02 for BCC_CSM; both are much higher than the uncorrected hindcasts. Applying the dynamic-analogue correction scheme in both models successfully improves prediction of the EASP decadal change in the late 1990s.
Liew, P. M.; Lee, C. Y.; Kuo, C. M.
The East Asian monsoon Holocene optimal period has been debated both about duration and whether conditions were a maximum in thermal conditions or in precipitation. In this study we show Holocene climate variability inferred by a forest reconstruction of a subalpine pollen sequence from peat bog deposits in central Taiwan, based on modern analogues of various altitudinal biomes in the region. A warmer interval occurred between 8 and 4 ka BP (calibrated 14C years) when the subtropical forests were more extensive. The Holocene thermal optimum is represented by an altitudinal tropical forest at 6.1-5.9 ka BP and 6.9 ka BP and only the latter was accompanied by wet conditions, indicating decoupling of thermal and precipitation mechanism in the middle Holocene. Abrupt and relative severe cold phases, shown by biome changes, occurred at about 11.2-11.0 ka BP; 7.5 ka BP; 7.2 ka BP; 7.1 ka BP; 5.2 ka BP, 5.0 ka BP and 4.9 ka BP. A spectral analysis of pollen of a relatively cold taxon — Salix, reveals that the time series is dominated by a 1500 yr periodicity and similar to the cold cycle reported in the marine records of Indian and western Pacific Oceans. The cold-warm conditions inferred by the change of forests show close relationship to solar energy in comparison with the production rate of Be-10.
Park, Chorong; Nam, Soohyun; Whittemore, Robin
It is important to understand East Asian immigrants (EAIs)' unique perspectives in managing diabetes in order to provide culturally-competent care. However, it is not known whether EAIs' perspectives are addressed in diabetes self-management interventions developed for EAIs. Therefore, a mixed-study review was conducted to identify EAIs' perspective from qualitative research (n = 9 studies) and to evaluate the components of EAI diabetes self-management interventions (n = 7). Themes from the qualitative synthesis demonstrated that EAIs have unique cultural values and traditional health beliefs while struggling with multi-contextual barriers due to immigration. The evaluation of EAI diabetes self-management interventions revealed that there was a lack of consensus on cultural strategies for EAIs' across the interventions. Addressing language barriers was the only factor consistently integrated in the cultural components of intervention by employing bilingual interventionists. EAIs' perspectives and experiences need to be incorporated in the future diabetes self-management interventions to better provide culturally-competent care.
Watanabe, Tsuyoshi; Kawamura, Takashi; Yamazaki, Atsuko; Murayama, Masafumi; Yamano, Hiroya
The Pacific Decadal Oscillation (PDO) is a dominant climate mode in the Pacific Ocean and thought to be related to seasonal to decadal changes in sea surface conditions. Colonies of long-living Porites coral, widely used to reconstruct monthly to century-scale tropical sea surface temperature and sea surface salinity records, were discovered near Koshiki Island, Japan (31°N, 129°E). A monthly resolved, 106 year δ18O record revealed that distinct decadal-scale variability was significantly correlated with the PDO index. Our comparison showed 1 to 3 years lead-lag correlation of summer coral δ18O with the winter PDO index, suggesting that the East Asian summer monsoon (EASM) may act as the driving force of winter PDO variability over the last 100 years. Cross-spectral analysis between the winter PDO index and summer coral δ18O suggested that recent and future global warming may lead to a more frequent and/or stronger teleconnection between EASM and PDO.
Lin, Renping; Zhu, Jiang; Zheng, Fei
The East Asian summer monsoon (EASM) experienced decadal transitions over the past few decades, and the associated "wetter-South-drier-North" shifts in rainfall patterns in China significantly affected the social and economic development in China. Two viewpoints stand out to explain these decadal shifts, regarding the shifts either a result of internal variability of climate system or that of external forcings (e.g. greenhouse gases (GHGs) and anthropogenic aerosols). However, most climate models, for example, the Atmospheric Model Intercomparison Project (AMIP)-type simulations and the Coupled Model Intercomparison Project (CMIP)-type simulations, fail to simulate the variation patterns, leaving the mechanisms responsible for these shifts still open to dispute. In this study, we conducted a successful simulation of these decadal transitions in a coupled model where we applied ocean data assimilation in the model free of explicit aerosols and GHGs forcing. The associated decadal shifts of the three-dimensional spatial structure in the 1990s, including the eastward retreat, the northward shift of the western Pacific subtropical high (WPSH), and the south-cool-north-warm pattern of the upper-level tropospheric temperature, were all well captured. Our simulation supports the argument that the variations of the oceanic fields are the dominant factor responsible for the EASM decadal transitions.
Yu, Rong; Jiang, Zhihong; Zhai, Panmao
The effect of urban land-use change in eastern China on the East Asian subtropical monsoon (EASTM) is investigated by using the Community Atmosphere Model version 5.1. Comparison of the results between the urban expansion and reference experiments shows that with the urban expansion, the land surface energy balance alters: surface net radiation and sensible heat fluxes enhance while the latent heat fluxes reduce. As a result, a significant increase in surface air temperature over eastern China is detected. The urban land-use change contributes to a change in the zonal land-sea temperature difference (LSTD), leading to a delay in the time when LSTD changes from positive to negative, and vice versa. Additionally, the onset and retreat dates of the EASTM are also delayed. Meanwhile, the rise in surface air temperature leads to formation of abnormal northerly air flows, which may be the reason for the slower northward movement of the EASTM and a more southward location of its northern boundary.
Yang, D.; Yang, X. Q.; Xie, Q.; Zhang, Y.; Ren, X.; Tang, Y.
Based on the historical forecasts of three quasi-operational multi-model ensemble (MME) systems, this study assesses the superiorities of the coupled MME over its contributing single-model ensembles (SMEs) and over the uncoupled atmospheric MME in predicting the seasonal variability of the Western North Pacific-East Asian summer monsoon. The seasonal prediction skill of the monsoon is measured by Brier skill score (BSS) in the sense of probabilistic forecast as well as by anomaly correlation (AC) in the sense of deterministic forecast. The probabilistic forecast skill of the MME is found to be always significantly better than that of each participating SME, while the deterministic forecast skill of the MME is even worse than that of some SME. The BSS is composed of reliability and resolution, two attributes characterizing probabilistic forecast skill. The probabilistic skill increase of the MME is dominated by the drastic improvement in reliability, while resolution is not always improved, similar to AC. A monotonous resolution-AC relationship is further found and qualitatively understood, whereas little relationship can be identified between reliability and AC. It is argued that the MME's success in improving the reliability possibly arises from an effective reduction of biases and overconfidence in forecast distributions. The coupled MME is much more skillful than the uncoupled atmospheric MME forced by persisted sea surface temperature (SST) anomalies. This advantage is mainly attributed to its better capability in capturing the evolution of the underlying seasonal SST anomaly.
Tyrlis, Evangelos; Å kerlak, Bojan; Sprenger, Michael; Wernli, Heini; Zittis, George; Lelieveld, Jos
A climatology of tropopause folds occurring over the Eastern Mediterranean and the Middle East (EMME) has been established using the ERA-Interim reanalyses for the years 1979-2012. The methodology employs an algorithm that detects folds at grid points where the vertical profile features multiple crossings of the dynamical tropopause and allows their classification according to their vertical extent. Our results confirm the findings of an earlier 1 year climatology that recognized a global "hot spot" of summertime fold activity between the eastern Mediterranean and central Asia, in the vicinity of the subtropical jet. Two distinct maxima of activity are identified over Turkey and Iran-Afghanistan where fold frequency exceeds 25%. Occasionally, medium and deep folds form over the two regions at surprisingly low latitudes. This summertime peak in fold activity diverges from the zonal mean seasonal cycle over the subtropics and is driven by the South Asian Monsoon. Starting in late spring, the EMME is gradually brought under the influence of the zonally asymmetric background state induced by the monsoon. As areas of sharply sloping isentropes develop especially over the eastern Mediterranean and Iran-Afghanistan, subsidence and fold formation are favored. Further investigation of the reanalysis data provided empirical evidence that the monsoon also drives the interannual variability of EMME fold activity. An upward trend in fold activity is identified, especially in May, attributed to the recent advanced monsoon onset and the deepening convective activity throughout summer, which promotes upper-level baroclinicity over the EMME and favors folding.
Huang, Junhao; Yoshitake, Hiraku; Zhang, Runzhi; Ito, Motomi
Abstract The genus Scleropteroides Colonnelli, 1979 (Ceutorhynchinae: Scleropterini) was revised on the basis of detailed morphological observations. The genus was redefined to include three species from East Asia: S. hypocrita (Hustache, 1916) is redescribed and recorded from northeastern China and northern Korea for the first time; S. horridulus (Voss, 1958) is redescribed with new records from southern Korea; S. insularis Voss, 1971 was moved from synonymy with S. hypocrita to that with S. horridulus (syn. n.), and S. longiprocessus Huang & Yoshitake, sp. n. is described as new, sympatric with S. hypocrita in Japan. All the species are associated with woody Rubus species (Rosaceae). A key to species, habitus photographs, illustrations of important characters, and distribution maps are provided for each species. PMID:25197212
Lee, Jung-Hyun; Choi, In-Su; Choi, Byoung-Hee; Yang, Sungyu; Choi, Goya
We sequenced the complete plastid genome (plastome) for Piper kadsura, a woody vine endemic to East Asia. This species is part of the largest genus within Piperaceae and its genome is almost identical to its congener P. cenocladum. The plastome for P. kadsura comprises 131 genes, including four unique rRNAs, 30 tRNAs, and 79 protein-coding genes. It retains ycf1 as an intact open reading frame. Our phylogenetic analysis demonstrated the monophyly of the Piper genus. The additional plastome sequence found in this evolutionarily and economically important genus will be a valuable, fundamental tool for future studies of phylogenetic relationships among basal angiosperms, and will provide a useful resource for molecular breeding programs.
Jin, Dong-Pil; Lee, Jung-Hyun; Xu, Bo; Choi, Byoung-Hee
The dynamic changes in land configuration during the Quaternary that were accompanied by climatic oscillations have significantly influenced the current distribution and genetic structure of warm-temperate forests in East Asia. Although recent surveys have been conducted, the historical migration of forest species via land bridges and, especially, the origins of Korean populations remains conjectural. Here, we reveal the genetic structure of Lespedeza buergeri, a warm-temperate shrub that is disjunctively distributed around the East China Sea (ECS) at China, Korea, and Japan. Two non-coding regions (rpl32-trnL, psbA-trnH) of chloroplast DNA (cpDNA) and the internal transcribed spacer of nuclear ribosomal DNA (nrITS) were analyzed for 188 individuals from 16 populations, which covered almost all of its distribution. The nrITS data demonstrated a genetic structure that followed geographic boundaries. This examination utilized AMOVA, comparisons of genetic differentiation based on haplotype frequency/genetic mutations among haplotypes, and Mantel tests. However, the cpDNA data showed contrasting genetic pattern, implying that this difference was due to a slower mutation rate in cpDNA than in nrITS. These results indicated frequent migration by this species via an ECS land bridge during the early Pleistocene that then tapered gradually toward the late Pleistocene. A genetic isolation between western and eastern Japan coincided with broad consensus that was suggested by the presence of other warm-temperate plants in that country. For Korean populations, high genetic diversity indicated the existence of refugia during the Last Glacial Maximum on the Korean Peninsula. However, their closeness with western Japanese populations at the level of haplotype clade implied that gene flow from western Japanese refugia was possible until post-glacial processing occurred through the Korea/Tsushima Strait land bridge.
Karanovic, Tomislav; Kim, Kichoon; Lee, Wonchoel
Abstract Definition of monophyletic supraspecific units in the harpacticoid subfamily Stenheliinae Brady, 1880 has been considered problematic and hindered by the lack of molecular or morphology based phylogenies, as well as by incomplete original descriptions of many species. Presence of a modified seta on the fifth leg endopod has been suggested recently as a synapomorphy of eight species comprising the redefined genus Stenhelia Boeck, 1865, although its presence was not known in S. pubescens Chislenko, 1978. We redescribe this species in detail here, based on our freshly collected topotypes from the Russian Far East. The other species redescribed in this paper was collected from the southern coast of South Korea and identified as the Chinese S. taiae Mu & Huys, 2002, which represents its second record ever and the first one in Korea. A fragment of the mtCOI gene was successfully PCR-amplified from two specimens of each species, which represents the first molecular data for this genus, and from additional 19 specimens belonging to six different species of other stenheliins from Korea and Russia. Reconstructed phylogenies confirm previously postulated monophyly of Stenhelia and polyphyly of the closely related genus Delavalia Brady, 1869. Average pairwise maximum likelihood distances between S. pubescens and S. taiae are only slightly above 10%, suggesting a very close relationship despite numerous newly discovered micro-morphological differences and despite macro-morphological similarities being probable plesiomorphies. PMID:24899857
Amiot, Romain; Wang, Xu; Zhou, Zhonghe; Wang, Xiaolin; Buffetaut, Eric; Lécuyer, Christophe; Ding, Zhongli; Fluteau, Frédéric; Hibino, Tsuyoshi; Kusuhashi, Nao; Mo, Jinyou; Suteethorn, Varavudh; Wang, Yuanqing; Xu, Xing; Zhang, Fusong
Early Cretaceous vertebrate assemblages from East Asia and particularly the Jehol Biota of northeastern China flourished during a period of highly debated climatic history. While the unique characters of these continental faunas have been the subject of various speculations about their biogeographic history, little attention has been paid to their possible climatic causes. Here we address this question using the oxygen isotope composition of apatite phosphate (δ ) from various reptile remains recovered from China, Thailand, and Japan. δ values indicate that cold terrestrial climates prevailed at least in this part of Asia during the Barremian-early Albian interval. Estimated mean air temperatures of about 10 ± 4 °C at midlatitudes (∼ 42 °N) correspond to present day cool temperate climatic conditions. Such low temperatures are in agreement with previous reports of cold marine temperatures during this part of the Early Cretaceous, as well as with the widespread occurrence of the temperate fossil wood genus Xenoxylon and the absence of thermophilic reptiles such as crocodilians in northeastern China. The unique character of the Jehol Biota is thus not only the result of its evolutionary and biogeographical history but is also due to rather cold local climatic conditions linked to the paleolatitudinal position of northeastern China and global icehouse climates that prevailed during this part of the Early Cretaceous.
Choi, In-Jin; Jin, Emilia Kyung; Han, Ji-Young; Kim, So-Young; Kwon, Young
The capability to simulate the diurnal variation of precipitation over East Asia region during the summertime of 2011 is investigated using five different cumulus parameterization schemes with the Weather Research and Forecasting model. A semidiurnal cycle with a 12 h interval over land and a diurnal cycle with a 24 h interval over ocean are commonly found in all simulations, consistent with the observed diurnal cycle. Two observed dominant peaks in the early morning and afternoon are reproduced in all simulations. With overestimated precipitation rate, however, the simulated afternoon peaks occur earlier than the observed peaks by 2 h for the Kain-Fritsch (KF) and Simplified Arakawa-Schubert schemes, and by 3 h for the Betts-Miller-Janjić and Tiedtke schemes. The overestimation of simulated precipitation frequency leads to amplitude and phase errors in the precipitation rate, and the early peak time of simulated precipitation intensity intensifies the phase error in the simulation over land. The KF scheme with alternative trigger function (KFtr) based on moisture advection provides slightly better results in terms of alleviating the overestimated precipitation rate and frequency and delaying the afternoon peaks. Additional sensitivity simulations based on the change of temperature perturbation in the trigger function of the KF and KFtr schemes demonstrate the afternoon peak tends to be delayed as temperature perturbation decreases, implying the significant role of convective initiation frequency in determining diurnal peaks of precipitation. Modulation of temperature perturbation alleviates the precipitation frequency bias, while it could not resolve the precipitation intensity bias.
Yao, Shuai-Lei; Luo, Jing-Jia; Huang, Gang
Regional climate projections are challenging because of large uncertainty particularly stemming from unpredictable, internal variability of the climate system. Here, we examine the internal variability-induced uncertainty in precipitation and surface air temperature (SAT) trends during 2005–2055 over East Asia based on 40 member ensemble projections of the Community Climate System Model Version 3 (CCSM3). The model ensembles are generated from a suite of different atmospheric initial conditions using the same SRES A1B greenhouse gas scenario. We find that projected precipitation trends are subject to considerably larger internal uncertainty and hence have lower confidence, compared to the projected SAT trends in both the boreal winter and summer. Projected SAT trends in winter have relatively higher uncertainty than those in summer. Besides, the lower-level atmospheric circulation has larger uncertainty than that in the mid-level. Based on k-means cluster analysis, we demonstrate that a substantial portion of internally-induced precipitation and SAT trends arises from internal large-scale atmospheric circulation variability. These results highlight the importance of internal climate variability in affecting regional climate projections on multi-decadal timescales. PMID:26930402
Zhang, Hongbin; Griffiths, Michael L.; Huang, Junhua; Cai, Yanjun; Wang, Canfa; Zhang, Fan; Cheng, Hai; Ning, Youfeng; Hu, Chaoyong; Xie, Shucheng
Previous research has shown a strong persistence for direct teleconnections between the East Asian summer monsoon (EASM) and high northern latitude climate variability during the last glacial and deglaciation, in particular between monsoon weakening and a reduced Atlantic meridional overturning circulation (AMOC). However, less attention has been paid to EASM strengthening as the AMOC was reinvigorated following peak Northern Hemisphere (NH) cooling. Moreover, climate model simulations have suggested a strong role for Antarctic meltwater discharge in modulating northward heat transport and hence NH warming, yet the degree to which Southern Hemisphere (SH) climate anomalies impacted the Asian monsoon region is still unclear. Here we present a new stalagmite oxygen-isotope record from the EASM affected region of central China, which documents two prominent stages of increased 18O-depleted moisture delivery to the region through the transition from Heinrich Stadial 1 (HS1) to the Bølling-Allerød (B-A) interstadial; this is in general agreement with the other monsoonal records from both NH and SH mid to low latitudes. Through novel comparisons with a recent iceberg-rafted debris (IRD) record from the Southern Ocean, we propose that the two-stage EASM intensification observed in our speleothem records were linked with two massive Antarctic icesheet discharge (AID) events at ∼16.0 ka and ∼14.7 ka, immediately following the peak HS1 stadial event. Notably, the large increase in EASM intensity at the beginning of the HS1/B-A transition (∼16 ka) is relatively muted in the NH higher latitudes, and better aligns with the changes observed in the SH, indicating the Antarctic and Southern Ocean perturbations could have an active role in driving the initial EASM strengthening at this time. Indeed, Antarctic freshwater input to the Southern Ocean during these AID events would have cooled the surrounding surface waters and caused an expansion of sea ice, restricting the
Li, Wenkai; Guo, Weidong; Xue, Yongkang; Fu, Congbin; Qiu, Bo
Land surface processes play an important role in the East Asian Summer Monsoon (EASM) system. Parameterization schemes of land surface processes may cause uncertainties in regional climate model (RCM) studies for the EASM. In this paper, we investigate the sensitivity of a RCM to land surface parameterization (LSP) schemes for long-term simulation of the EASM. The Weather Research and Forecasting (WRF) Model coupled with four different LSP schemes (Noah-MP, CLM4, Pleim-Xiu and SSiB), hereafter referred to as Sim-Noah, Sim-CLM, Sim-PX and Sim-SSiB respectively, have been applied for 22-summer EASM simulations. The 22-summer averaged spatial distributions and strengths of downscaled large-scale circulation, 2-m temperature and precipitation are comprehensively compared with ERA-Interim reanalysis and dense station observations in China. Results show that the downscaling ability of RCM for the EASM is sensitive to LSP schemes. Furthermore, this study confirms that RCM does add more information to the EASM compared to reanalysis that imposes the lateral boundary conditions (LBC) because it provides 2-m temperature and precipitation that are with higher resolution and more realistic compared to LBC. For 2-m temperature and monsoon precipitation, Sim-PX and Sim-SSiB simulations are more consistent with observation than simulations of Sim-Noah and Sim-CLM. To further explore the physical and dynamic mechanisms behind the RCM sensitivity to LSP schemes, differences in the surface energy budget between simulations of Ens-Noah-CLM (ensemble mean averaging Sim-Noah and Sim-CLM) and Ens-PX-SSiB (ensemble mean averaging Sim-PX and Sim-SSiB) are investigated and their subsequent impacts on the atmospheric circulation are analyzed. It is found that the intensity of simulated sensible heat flux over Asian continent in Ens-Noah-CLM is stronger than that in Ens-PX-SSiB, which induces a higher tropospheric temperature in Ens-Noah-CLM than in Ens-PX-SSiB over land. The adaptive
Yu, Shimei; Xiao, Zuo; Zhao, Biqiang; Zhang, Donghe; Hao, Yongqiang
The mechanism of the longitudinal difference of ionospheric electron density is in general attributed to the thermospheric wind effect modulated by the local geomagnetic declination. Although this mechanism is tested in many case studies, there are other possible factors such as solar activity and so on which still need further investigations. In this paper, TEC data from two Chinese GPS stations located at almost same geographic latitudes but with a wide longitude span (~38°) are used to study the morphological features of longitudinal differences under various geophysical conditions. A parameter Rew is defined as a normalized measure of the TEC difference between the two stations. All the observed temporal variations of Rew are analyzed statistically, with the results showing that negative east-west differences (Western TEC>Eastern TEC) in the noontime are pronounced during Day of Year (DoY) 90-270, while nighttime positive differences (Western TEC
Ross, J. Ole; Ceranna, Lars
The radionuclide component of the International Monitoring System (IMS) to verify compliance with the Comprehensive Nuclear-Test-Ban Treaty (CTBT) is in place to detect tiny traces of fission products from nuclear explosions in the atmosphere. The challenge for the interpretation of IMS radionuclide data is to discriminate radionuclide sources of CTBT relevance against emissions from nuclear facilities. Remarkable activity concentrations of Ba/La-140 occurred at the IMS radionuclide stations RN 37 (Okinawa) and RN 58 (Ussurysk) mid of May 2010. In those days also an elevated Xe-133 level was measured at RN 38 (Takasaki). Additional regional measurements of radioxenon were reported in the press and further analyzed in various publications. The radionuclide analysis gives evidence for the presence of a nuclear fission source between 10 and 12 May 2010. Backward Atmospheric Transport Modelling (ATM) with HYSPLIT driven by 0.2° ECMWF meteorological data for the IMS samples indicates that, assuming a single source, a wide range of source regions is possible including the Korean Peninsula, the Sea of Japan (East Sea), and parts of China and Russia. Further confinement of the possible source location can be provided by atmospheric backtracking for the assumed sampling periods of the reported regional xenon measurements. New studies indicate a very weak seismic event at the DPRK test site on early 12 May 2010. Forward ATM for a pulse release caused by this event shows fairly good agreement with the observed radionuclide signature. Nevertheless, the underlying nuclear fission scenario remains quite unclear and speculative even if assuming a connection between the waveform and the radionuclide event.
Xing, Wen; Wang, Bin; Yim, So-Young
The interannual variation of East Asia summer monsoon (EASM) rainfall exhibits considerable differences between early summer [May-June (MJ)] and peak summer [July-August (JA)]. The present study focuses on peak summer. During JA, the mean ridge line of the western Pacific subtropical High (WPSH) divides EASM domain into two sub-domains: the tropical EA (5°N-26.5°N) and subtropical-extratropical EA (26.5°N-50°N). Since the major variability patterns in the two sub-domains and their origins are substantially different, the Part I of this study concentrates on the tropical EA or Southeast Asia (SEA). We apply the predictable mode analysis approach to explore the predictability and prediction of the SEA peak summer rainfall. Four principal modes of interannual rainfall variability during 1979-2013 are identified by EOF analysis: (1) the WPSH-dipole sea surface temperature (SST) feedback mode in the Northern Indo-western Pacific warm pool associated with the decay of eastern Pacific El Niño/Southern Oscillation (ENSO), (2) the central Pacific-ENSO mode, (3) the Maritime continent SST-Australian High coupled mode, which is sustained by a positive feedback between anomalous Australian high and sea surface temperature anomalies (SSTA) over Indian Ocean, and (4) the ENSO developing mode. Based on understanding of the sources of the predictability for each mode, a set of physics-based empirical (P-E) models is established for prediction of the first four leading principal components (PCs). All predictors are selected from either persistent atmospheric lower boundary anomalies from March to June or the tendency from spring to early summer. We show that these four modes can be predicted reasonably well by the P-E models, thus they are identified as the predictable modes. Using the predicted PCs and the corresponding observed spatial patterns, we have made a 35-year cross-validated hindcast, setting up a bench mark for dynamic models' predictions. The P-E hindcast
Singh, Gajinder Pal; Sharma, Amit
Resistance to frontline anti-malarial drugs, including artemisinin, has repeatedly arisen in South-East Asia, but the reasons for this are not understood. Here we test whether evolutionary constraints on Plasmodium falciparum strains from South-East Asia differ from African strains. We find a significantly higher ratio of non-synonymous to synonymous polymorphisms in P. falciparum from South-East Asia compared to Africa, suggesting differences in the selective constraints on P. falciparum genome in these geographical regions. Furthermore, South-East Asian strains showed a higher proportion of non-synonymous polymorphism at conserved positions, suggesting reduced negative selection. There was a lower rate of mixed infection by multiple genotypes in samples from South-East Asia compared to Africa. We propose that a lower mixed infection rate in South-East Asia reduces intra-host competition between the parasite clones, reducing the efficiency of natural selection. This might increase the probability of fixation of fitness-reducing mutations including drug resistant ones. PMID:27853513
Sato, K.; Tsuyoshi, O.; Endo, T.; Yagoh, H.; Matsuda, K.
Emission of sulfur and nitrogen compounds in Asian region has been remarkably increased with recent rapid economical growth (Ohara et al., 2007). To appropriately assess the influence of air pollutants on the ecosystem, it is important to quantitatively determine the atmospheric deposition of air pollutants. Here, Seasonal and annual variations and regional characteristics of estimated wet and dry deposition amounts at 27 monitoring sites of Acid Deposition Monitoring Network in East Asia (EANET) from 2003 to 2009 are discussed. Wet deposition sample was collected every 24 hours or 1 week by a wet only sampler. Wet deposition amounts were calculated by the product of the volume-weighted concentrations of ionic species (SO42-, NO3-, and NH4+) in the precipitation and precipitation amount measured by a standard rain gauge at each site. Dry deposition amount was estimated by the inferential method which was originated the model developed by Wesely and Hicks (1977) and modified by Matsuda (2008). The components examined for dry deposition were sulfur compounds (gaseous SO2 and particulate SO42-) and nitrogen compounds (gaseous HNO3 and NH3, particulate NO3- and NH4+). Dry deposition was calculated by the product of the deposition velocity estimated by the inferential method for forest and grass surfaces and the monitored air concentration of each compound. The mean annual dry deposition amounts for sulfur and nitrogen compounds in Japanese sites were in the range of 5-37 and 7-50 mmol m-2 year-1, respectively. The regional characteristics of dry deposition amounts in Japan were similar between sulfur and nitrogen compounds, which showed higher deposition in the Sea of Japan side and the western Japan. The mean annual total (wet + dry) deposition amounts for sulfur and nitrogen compounds in Japanese sites were in the range of 28-77 and 22-130 mmol m-2 year-1, respectively. The contributions of dry deposition to the total deposition amounts were 10-55% and 13-56% for
The Indonesian Throughflow (ITF) links upper ocean waters of the west Pacific and Indian Ocean, modulates heat and fresh water budgets between these oceans and in turn plays an important role in global climate change. It was suggested that East Asian monsoon and El Niño-Southern Oscillation (ENSO) exert a strong influence on flux, water properties and vertical stratification of the modern ITF. Possible link of the ITF to ENSO is also supported by significant linear correlation (R2=0.43) between thermocline temperature (TT) of the ITF outflow and NINO3.4 index over the past 50 years. In this work, seawater temperatures and salinity and vertical thermal structure of the ITF outflow since the last glacial were reconstructed from Core SO18462 that was retrieved from exit of the ITF to the Timor Sea (TS) (Holbourn et al., 2011). The records of Core SO18462 were then compared with records of Core 3cBX that were considered to reveal ENSO-like conditions in the center of the western Pacific warm pool (WPWP) (Sagawa et al., 2012). The results show that surface waters were comparable in the TS and the WPWP prior to ~16ka, and then diverged with much freshening in the TS. On the contrary, thermocline waters were largely diverged, warmer and more saline in the TS than in the WPWP, and then started to converge from ~16ka. Sea surface temperature (SST) remained over 28°C (the temperature defining range of modern WPWP) in both of the regions during 11.5-6ka. SST then slightly decreased below 28°C in the TS when it kept all the way above 28°C in the WPWP towards the late Holocene. In contrast, TT and thermocline depth remained overall unchanged in the WPWP, concurring with decreasing of TT and shoaling of thermocline in the TS during 11.5-6ka. After 6ka, thermocline continued shoaling in the TS, when TT remained decreasing and thermocline salinity approached to be similar in both of the regions. Comparison of TS and WPWP records conspicuously disclose two categories of
Fan, Jiawei; Xiao, Jule; Wen, Ruilin; Zhang, Shengrui; Wang, Xu; Cui, Linlin; Li, He; Xue, Dingshuai; Yamagata, Hideki
Teleconnections to the high latitudes, forcing by the tropical oceans and solar variability have all been suggested as dominant factors in the sub-millennial global climate changes, yet there is little consensus as to the relative importance of these factors for the East Asian summer monsoon (EASM) variability. This study presents the results of high-resolution analyses of Ca and Mg concentrations, Mg/Ca ratio, δ18O and δ13C values of endogenic calcites from a sediment core from Dali Lake in the EASM margin, in order to investigate the sub-millennial EASM variability and its possible driving forces during the last 6 kyrs. Increases in these chemical proxy data were interpreted as drought events in the region due to the intensive evaporation losses overwhelming the water input to the lake. The chemical proxy data in this study combined with multi-proxy indicators including grain size component and total organic carbon concentrations from the same sediment core imply that declines in the EASM intensity may have played a dominant role in triggering the drought events during the last 6 kyrs. The results indicate that the EASM intensity significantly declined at the intervals of 5.8-4.75, 3.2-2.8, 1.65-1.15 and 0.65-0.2 kyrs BP. Large declines in the EASM intensity during the last 6 kyrs correspond in time to occurrences of ice-rafted debris in the North Atlantic, indicating that millennial-to-centennial scale changes in the EASM intensity were mainly controlled by climatic processes occurring in the northern high latitudes. These data imply that persistent global warming may be favorable for the strengthening of the EASM circulation and for the transportation of more rainfall to the semi-arid regions of northern China on sub-millennial scales.
Huang, Wei-Hsin; Hwang, Lee-Ching; Chan, Hsin-Lung; Lin, Hsiang-Yu; Lin, Yung-Hsiang
Objective This study aimed to examine single-nucleotide polymorphisms (SNPs) of seven previously reported obesity genes in East Asians and to analyse their associations and synergistic effects on obesity in the Taiwanese population. Design Cross-sectional study. Setting One medical centre in northern Taiwan. Participants A total of 323 non-obese and 264 obese participants were recruited. The threshold for obesity in this study was a body mass index of ≥27 kg/m2, as defined by the Ministry of Health and Welfare in Taiwan. The study was performed with the approval of the institutional review board of MacKay Memorial Hospital, Taipei, Taiwan (application number 12MMHIS106). Outcome measures We analysed the genotype distributions of seven SNPs localising to the PPARγ2, GNB3, SDC3, ADRB2, FTO, PPARγ and ESR1 genes in obese and non-obese groups and then paired obesity-related SNPs to determine if they have synergistic effects on obesity. Results Analysis of the genotype distributions in obese and non-obese groups revealed only a significant positive correlation between an SNP in rs2282440-syndecan 3 (SDC3) and obesity in the Taiwanese population (p=0.006). In addition, the T/T genotype of SDC3 was significantly associated with a larger waist and hip circumference, higher body fat percentage and lower high-density lipoprotein cholesterol. Moreover, the combination of the rs2282440-SDC3T/T genotype with the rs1801282-peroxisome proliferator-activated receptor-gamma2 gene (PPARγ2) G carrier genotype was strongly associated with obesity (OR=6.77). Conclusions We found that the rs2282440-SDC3T/T genotype is associated with obesity in the Taiwanese population. Furthermore, there is a synergistic effect of the high-risk alleles of the SDC3 and PPARγ2 genes on the obese phenotype in the Taiwanese population. Trial registration number 12MMHIS106; Results. PMID:27515755
Safieddine, S.; Boynard, A.; Hao, N.; Huang, F.; Wang, L.; Ji, D.; Barret, B.; Ghude, S. D.; Coheur, P.-F.; Hurtmans, D.; Clerbaux, C.
Satellite measurements from the thermal Infrared Atmospheric Sounding Interferometer (IASI), the Measurements of OZone and water vapor by in-service AIrbus airCraft (MOZAIC), as well as observations from ground based stations, are used to assess the tropospheric ozone (O3) variability during the East Asian Summer Monsoon (EASM). Six years [2008-2013] of IASI data analysis reveals the ability of the instrument to detect the onset and the progression of the monsoon reflected by a decrease in the tropospheric [0-6] km O3 column due to the EASM, and to reproduce this decrease from one year to the other. Focusing on the period of May-August 2011, taken as an example year, IASI data show clear inverse relationship between tropospheric [0-6] km O3 on one hand and meteorological parameters such as cloud cover, relative humidity and wind speed, on the other hand. Aircraft data from the MOZAIC project at Hyderabad, Nanjing and Guangzhou are used to validate the IASI data and to assess the effect of the monsoon on the vertical distribution of the tropospheric O3 at different locations. Results show good agreement with a correlation coefficient of 0.74 between the [0-6] km O3 column derived from IASI and MOZAIC. The aircraft data show a decrease in the tropospheric O3 that is more important in the free troposphere than in the boundary layer and at Hyderabad than at the other two Chinese cities. Ground station data at different locations in India and China show a spatiotemporal dependence on meteorology during the monsoon, with decrease up to 22 ppbv in Hyderabad, and up to 5 ppbv in the North China Plain.
Guo, C.; Yu, J.; Ho, T.-Y.; Wang, L.; Song, S.; Kong, L.; Liu, H.
Recent studies have demonstrated atmospheric deposition as an important source of bioreactive compounds to the ocean. The South China Sea (SCS), where aerosol loading is among the highest in the world, however, is poorly studied, particularly on the in situ response of phytoplankton community structures to atmospheric deposition. By conducting a series of microcosm bioassays at different hydrographical locations and simulating different aerosol event scales, we observed both positive and negative responses to the input of East Asian (EA) aerosol with high nitrogen (N) and trace metal contents, in terms of biomass, composition and physiological characteristics of phytoplankton communities. High levels of aerosol loading relieved phytoplankton nitrogen and trace metal limitations in SCS, and thus increased total phytoplankton biomass, enhanced their physiological indicators (e.g. photosynthetic efficiency) and shifted phytoplankton assemblages from being dominated by picoplankton to microphytoplanton, especially diatoms. However, under low levels of aerosol loading, the composition shift and biomass accumulation were not apparent, suggesting that the stimulation effects might be counterbalanced by enhanced grazing mortality indicated by increased abundance of protist grazers. Trace metal toxicity of the aerosols might also be the reason for the reduction of picocyanobacteria when amended with high EA aerosols. The magnitude and duration of the deposition event, as well as the hydrographical and trophic conditions of receiving waters are also important factors when predicting the influence of an aerosol deposition event. Our results demonstrated different responses of phytoplankton and microbial food web dynamics to different scales of atmospheric input events in SCS and highlighted the need for achieving an accurate comprehension of atmospheric nutrient on the biogeochemical cycles of the oceans.
Safieddine, Sarah; Boynard, Anne; Hao, Nan; Huang, Fuxiang; Wang, Lili; Ji, Dongsheng; Barret, Brice; Ghude, Sachin D.; Coheur, Pierre-François; Hurtmans, Daniel; Clerbaux, Cathy
Satellite measurements from the thermal Infrared Atmospheric Sounding Interferometer (IASI), aircraft data from the MOZAIC/IAGOS project, as well as observations from ground-based stations, are used to assess the tropospheric ozone (O3) variability during the East Asian Summer Monsoon (EASM). Six years 2008-2013 of IASI data analysis reveals the ability of the instrument to detect the onset and the progression of the monsoon seen by a decrease in the tropospheric 0-6 km O3 column due to the EASM, and to reproduce this decrease from one year to the other. The year-to-year variability is found to be mainly dependent on meteorology. Focusing on the period of May-August 2011, taken as an example year, IASI data show clear inverse relationship between tropospheric 0-6 km O3 on one hand and meteorological parameters such as cloud cover, relative humidity and wind speed, on the other hand. Aircraft data from the MOZAIC/IAGOS project for the EASM of 2008-2013 are used to validate the IASI data and to assess the effect of the monsoon on the vertical distribution of the tropospheric O3 at different locations. Results show good agreement with a correlation coefficient of 0.73 (12 %) between the 0-6 km O3 column derived from IASI and aircraft data. IASI captures very well the inter-annual variation of tropospheric O3 observed by the aircraft data over the studied domain. Analysis of vertical profiles of the aircraft data shows a decrease in the tropospheric O3 that is more important in the free troposphere than in the boundary layer and at 10-20° N than elsewhere. Ground station data at different locations in India and China show a spatiotemporal dependence on meteorology during the monsoon, with a decrease up to 22 ppbv in Hyderabad, and up to 5 ppbv in the North China Plain.
Schaafsma, Anne; Deurenberg, Paul; Calame, Wim; van den Heuvel, Ellen G H M; van Beusekom, Christien; Hautvast, Jo; Sandjaja; Bee Koon, Poh; Rojroongwasinkul, Nipa; Le Nguyen, Bao Khanh; Parikh, Panam; Khouw, Ilse
Nutrition is a well-known factor in the growth, health and development of children. It is also acknowledged that worldwide many people have dietary imbalances resulting in over- or undernutrition. In 2009, the multinational food company FrieslandCampina initiated the South East Asian Nutrition Survey (SEANUTS), a combination of surveys carried out in Indonesia, Malaysia, Thailand and Vietnam, to get a better insight into these imbalances. The present study describes the general study design and methodology, as well as some problems and pitfalls encountered. In each of these countries, participants in the age range of 0·5-12 years were recruited according to a multistage cluster randomised or stratified random sampling methodology. Field teams took care of recruitment and data collection. For the health status of children, growth and body composition, physical activity, bone density, and development and cognition were measured. For nutrition, food intake and food habits were assessed by questionnaires, whereas in subpopulations blood and urine samples were collected to measure the biochemical status parameters of Fe, vitamins A and D, and DHA. In Thailand, the researchers additionally studied the lipid profile in blood, whereas in Indonesia iodine excretion in urine was analysed. Biochemical data were analysed in certified laboratories. Study protocols and methodology were aligned where practically possible. In December 2011, data collection was finalised. In total, 16,744 children participated in the present study. Information that will be very relevant for formulating nutritional health policies, as well as for designing innovative food and nutrition research and development programmes, has become available.
Yang, Dejian; Yang, Xiu-Qun; Xie, Qian; Zhang, Yaocun; Ren, Xuejuan; Tang, Youmin
Based on historical forecasts of three quasi-operational multimodel ensemble (MME) systems, this study assesses the superiority of coupled MME over contributing single-model ensembles (SMEs) and over uncoupled atmospheric MME in predicting the Western North Pacific-East Asian summer monsoon variability. The probabilistic and deterministic forecast skills are measured by Brier skill score (BSS) and anomaly correlation (AC), respectively. A forecast-format-dependent MME superiority over SMEs is found. The probabilistic forecast skill of the MME is always significantly better than that of each SME, while the deterministic forecast skill of the MME can be lower than that of some SMEs. The MME superiority arises from both the model diversity and the ensemble size increase in the tropics, and primarily from the ensemble size increase in the subtropics. The BSS is composed of reliability and resolution, two attributes characterizing probabilistic forecast skill. The probabilistic skill increase of the MME is dominated by the dramatic improvement in reliability, while resolution is not always improved, similar to AC. A monotonic resolution-AC relationship is further found and qualitatively explained, whereas little relationship can be identified between reliability and AC. It is argued that the MME's success in improving the reliability arises from an effective reduction of the overconfidence in forecast distributions. Moreover, it is examined that the seasonal predictions with coupled MME are more skillful than those with the uncoupled atmospheric MME forced by persisting sea surface temperature (SST) anomalies, since the coupled MME has better predicted the SST anomaly evolution in three key regions.
McPherson, S; Valappil, M; Moses, S E; Eltringham, G; Miller, C; Baxter, K; Chan, A; Shafiq, K; Saeed, A; Qureshi, R; Hudson, M; Bassendine, M F
Chronic infection with the hepatitis B virus (HBV) is a frequent cause of cirrhosis and liver cancer. Targeted HBV screening is recommended by the Centre for Disease Control (CDC) and Prevention for subjects born in countries with >2% HBV prevalence. However, there are no UK guidelines. Here, we applied the (CDC) recommendations to the British-Chinese and British-South Asian community of North-East (NE) England. British-Chinese and South Asian subjects were invited to attend for HBV education and screening sessions held in community centres. Hepatitis B surface antigen (HBsAg) and hepatitis B core total antibody (HBcAb) were tested with dry blood spot tests. South Asians were also tested for hepatitis C antibody (HCVAb). A total of 1126 subjects (606 Chinese and 520 South Asian) were screened. Sixty-two (5.5%) were HBsAg positive. Ten of these reported a previous diagnosis of HBV. The prevalence of HBsAg positivity was 4.6% when previously diagnosed individuals were excluded. The HBsAg prevalence was significantly higher in the Chinese subjects compared with South Asians (8.7% VS. 1.7% P < 0.001). In Chinese subjects, HBsAg positivity was highest in subjects born in Vietnam (17.4%), followed by China (11%), Hong Kong (7.8%) and the UK (6.7%). Subjects from Pakistan had the highest HBsAg and HCV Ab prevalence in the South Asians (3.1% and 1.8%, respectively). Ten percentage of HBsAg positive patients who had follow-up assessment had active disease requiring antiviral treatment. Undiagnosed HBV infection was above the 2% threshold for screening suggested by the CDC in the British-Chinese and Pakistani community of NE England, which provides evidence for a UK HBV-targeted screening programme.
Wu, Li-Wei; Yen, Shen-Horn; Lees, David C; Lu, Chih-Chien; Yang, Ping-Shih; Hsu, Yu-Feng
The phylogenetic status of the well-known Asian butterflies often known as Agehana (a species group, often treated as a genus or a subgenus, within Papilio sensu lato) has long remained unresolved. Only two species are included, and one of them especially, Papilio maraho, is not only rare but near-threatened, being monophagous on its vulnerable hostplant, Sassafras randaiense (Lauraceae). Although the natural history and population conservation of "Agehana" has received much attention, the biogeographic origin of this group still remains enigmatic. To clarify these two questions, a total of 86 species representatives within Papilionidae were sampled, and four genes (concatenated length 3842 bp) were used to reconstruct their phylogenetic relationships and historical scenarios. Surprisingly, "Agehana" fell within the American Papilio subgenus Pterourus and not as previously suggested, phylogenetically close to the Asian Papilio subgenus Chilasa. We therefore formally synonymize Agehana with Pterourus. Dating and biogeographic analysis allow us to infer an intercontinental dispersal of an American ancestor of Asian Pterourus in the early Miocene, which was coincident with historical paleo-land bridge connections, resulting in the present "East Asia-America" disjunction distribution. We emphasize that species exchange between East Asia and America seems to be a quite frequent occurrence in butterflies during the Oligocene to Miocene climatic optima.
Wu, Li-Wei; Lu, Chih-Chien; Yang, Ping-Shih; Hsu, Yu-Feng
The phylogenetic status of the well-known Asian butterflies often known as Agehana (a species group, often treated as a genus or a subgenus, within Papilio sensu lato) has long remained unresolved. Only two species are included, and one of them especially, Papilio maraho, is not only rare but near-threatened, being monophagous on its vulnerable hostplant, Sassafras randaiense (Lauraceae). Although the natural history and population conservation of “Agehana” has received much attention, the biogeographic origin of this group still remains enigmatic. To clarify these two questions, a total of 86 species representatives within Papilionidae were sampled, and four genes (concatenated length 3842 bp) were used to reconstruct their phylogenetic relationships and historical scenarios. Surprisingly, “Agehana” fell within the American Papilio subgenus Pterourus and not as previously suggested, phylogenetically close to the Asian Papilio subgenus Chilasa. We therefore formally synonymize Agehana with Pterourus. Dating and biogeographic analysis allow us to infer an intercontinental dispersal of an American ancestor of Asian Pterourus in the early Miocene, which was coincident with historical paleo-land bridge connections, resulting in the present “East Asia-America” disjunction distribution. We emphasize that species exchange between East Asia and America seems to be a quite frequent occurrence in butterflies during the Oligocene to Miocene climatic optima. PMID:26484776
Shin, Sung-Kyun; Müller, Detlef; Lee, K. H.; Shin, D.; Kim, Y. J.; Noh, Y. M.
We use five years (2009 - 2013) of multiwavelength Raman lidar measurements at Gwangju, Korea (35.10° N, 126.53° E) for the identification of changes of optical properties of East Asian dust in dependence of its transport path over China. Profiles of backscatter and extinction coefficients, lidar ratios, and backscatter-related Ångström exponents (wavelength pair 355/532nm) were measured at Gwangju. Linear particle depolarization ratios were used to identify East Asian dust layers. We used backward trajectory modelling to identify the pathway and the vertical position of dust-laden air masses over China during long-range transport. Most cases of Asian dust events can be described by the emission of dust in desert areas and subsequent transport over highly polluted regions of China. The Asian dust plumes could be categorized into two classes according to the height above ground in which these plumes were transported: (I) the dust layers passed over China at high altitude levels until arrival over Gwangju, and (II) the Asian dust layers were transported near the surface and the lower troposphere over industrialized areas before they arrived over Gwangju. We find that the optical characteristics of these mixed Asian dust layers over Gwangju differ in dependence of their vertical position above ground over China and the change of height above ground during transport. The mean linear particle depolarization ratio was 0.21±0.06 (at 532 nm), the mean lidar ratios were 52±7 sr at 355 nm and 53±8 sr at 532 nm, and the mean Ångström exponent was 0.74±0.31 in case I. In contrast, plumes transported at lower altitudes (case II) showed low depolarization ratios, and higher lidar ratio and Ångström exponents. The mean linear particle depolarization ratio was 0.13 ± 0.04, the mean lidar ratios were 63±9 sr at 355 nm and 62±8 sr at 532 nm, respectively, and the mean Ångström exponent was 0.98±0.51. These numbers show that the optical characteristics of mixed
Liu, Guiyou; Wang, Haiyang; Liu, Jiafeng; Li, Jingbo; Li, Hali; Ma, Guoda; Jiang, Yongshuai; Chen, Zugen; Zhao, Bin; Li, Keshen
Large-scale genomewide association studies have reported that the CLU rs11136000 polymorphism is significantly associated with Alzheimer's disease (AD) in people of Caucasian ancestry. Recently, this association was investigated in Asian populations (Chinese, Japanese, and Korean). However, these studies reported either a weak association or no association between the rs11136000 polymorphism and AD. We believe that this discrepancy may be caused by the relatively small sample size of the previous studies and the genetic heterogeneity of the rs11136000 polymorphism in AD among different populations. For this study, we searched the PubMed and AlzGene databases. We selected 18 independent studies (6 studies of Asian populations and 12 of populations of Caucasian ancestry) that evaluated the association between the rs11136000 polymorphism and AD using a case-control experimental design. We evaluated the genetic heterogeneity of the rs11136000 polymorphism in Caucasian and Asian populations. We then investigated the rs11136000 polymorphism by a meta-analysis in Asian populations using allele, dominant, and recessive models. We identified a significant association between rs11136000 and AD with the allele model (P = 2.00 × 10(-4)) and the dominant model (P = 5.00 × 10(-3)). Meanwhile, a similar genetic risk of the rs11136000 polymorphism in AD was observed in Asian and Caucasian populations. Further meta-analysis in pooled Asian and Caucasian populations indicated a more significant association with the allele (P = 8.30 × 10(-24)), dominant (P = 4.46 × 10(-17)), and recessive (P = 3.92 × 10(-12)) models. Collectively, our findings from this meta-analysis indicate that the effect of the CLU rs11136000 polymorphism on AD risk in Asian cohorts (Chinese, Japanese, and Korean) is consistent with the protective effect observed in Caucasian AD cohorts.
Liu, J.; Horowitz, L. W.; Lau, N.; Fan, S.; Tao, S.; Mauzerall, D. L.; Levy, H.
Short-lived anthropogenic pollutants (such as ozone and aerosols) not only degrade ambient air quality and influence human health, but also play an important role in scattering/absorbing atmospheric radiation and disturbing regional climate. Due to the rapid industrialization, anthropogenic emissions from East Asia (EA) have increased substantially during the past decades. At the same time, EA has experienced a changing climate in terms of surface temperature and precipitation. In order to understand to what extent that EA short-lived anthropogenic emissions could influence domestic and downwind air quality (e.g. surface O3 and PM2.5), and explore the potential linkage between hemispheric-scale climate perturbation and regional anthropogenic forcing, we simulate global climate and chemical compositions during 1981-2000 based on the coupled general circulation model CM3 for atmosphere (with interactive tropospheric and stratospheric chemistry), oceans, land and sea ice, recently developed at Geophysical Fluid Dynamics Laboratory (GFDL/NOAA). We also conduct a parallel sensitivity simulation which is identical to the base simulation but with all anthropogenic emissions over EA turned off. The difference between the base and sensitivity simulations represents the short-term response of the Northern Hemispheric climate system and atmospheric composition to the perturbation of regional anthropogenic forcing. We find that East Asian short-lived anthropogenic emissions exert significant adverse impacts on local air quality during 1981-2000, accounting for 10-30ppbV daily-averaged O3 over Eastern China in JJA. In particular, EA anthropogenic emissions elevate the summertime daily maximum 8-hour average ozone (MDA8 O3) by 30-40ppbV over the North China Plain, where the typical background MDA8 ozone ranges 30 to 45ppbV. In addition, the surface PM2.5 concentrations peak at the same season and over the same region, with a seasonal mean of 10-30ug/m3, mostly contributed from
We tested two methods for dataset generation and model construction, and three tree-classifier variants to identify the most parsimonious and thematically accurate mapping methodology for the SW ReGAP project. Competing methodologies were tested in the East Great Basin mapping un...
Dundes, Lauren; Cho, Eunice; Kwak, Spencer
To better understand factors underlying educational and career choices, this study used both survey data from an online networking tool and data collected in college classrooms to gauge differences between Asians (primarily Korean) and white students in the United States. More Asians (41%) than whites (9%) prioritized prestige over happiness,…
Qiu, Jingya; Darabos, Christian
ABSTRACT Genome‐wide association studies (GWAS) have led to the discovery of over 200 single nucleotide polymorphisms (SNPs) associated with type 2 diabetes mellitus (T2DM). Additionally, East Asians develop T2DM at a higher rate, younger age, and lower body mass index than their European ancestry counterparts. The reason behind this occurrence remains elusive. With comprehensive searches through the National Human Genome Research Institute (NHGRI) GWAS catalog literature, we compiled a database of 2,800 ancestry‐specific SNPs associated with T2DM and 70 other related traits. Manual data extraction was necessary because the GWAS catalog reports statistics such as odds ratio and P‐value, but does not consistently include ancestry information. Currently, many statistics are derived by combining initial and replication samples from study populations of mixed ancestry. Analysis of all‐inclusive data can be misleading, as not all SNPs are transferable across diverse populations. We used ancestry data to construct ancestry‐specific human phenotype networks (HPN) centered on T2DM. Quantitative and visual analysis of network models reveal the genetic disparities between ancestry groups. Of the 27 phenotypes in the East Asian HPN, six phenotypes were unique to the network, revealing the underlying ancestry‐specific nature of some SNPs associated with T2DM. We studied the relationship between T2DM and five phenotypes unique to the East Asian HPN to generate new interaction hypotheses in a clinical context. The genetic differences found in our ancestry‐specific HPNs suggest different pathways are involved in the pathogenesis of T2DM among different populations. Our study underlines the importance of ancestry in the development of T2DM and its implications in pharmocogenetics and personalized medicine. PMID:27061195
Qiu, Jingya; Moore, Jason H; Darabos, Christian
Genome-wide association studies (GWAS) have led to the discovery of over 200 single nucleotide polymorphisms (SNPs) associated with type 2 diabetes mellitus (T2DM). Additionally, East Asians develop T2DM at a higher rate, younger age, and lower body mass index than their European ancestry counterparts. The reason behind this occurrence remains elusive. With comprehensive searches through the National Human Genome Research Institute (NHGRI) GWAS catalog literature, we compiled a database of 2,800 ancestry-specific SNPs associated with T2DM and 70 other related traits. Manual data extraction was necessary because the GWAS catalog reports statistics such as odds ratio and P-value, but does not consistently include ancestry information. Currently, many statistics are derived by combining initial and replication samples from study populations of mixed ancestry. Analysis of all-inclusive data can be misleading, as not all SNPs are transferable across diverse populations. We used ancestry data to construct ancestry-specific human phenotype networks (HPN) centered on T2DM. Quantitative and visual analysis of network models reveal the genetic disparities between ancestry groups. Of the 27 phenotypes in the East Asian HPN, six phenotypes were unique to the network, revealing the underlying ancestry-specific nature of some SNPs associated with T2DM. We studied the relationship between T2DM and five phenotypes unique to the East Asian HPN to generate new interaction hypotheses in a clinical context. The genetic differences found in our ancestry-specific HPNs suggest different pathways are involved in the pathogenesis of T2DM among different populations. Our study underlines the importance of ancestry in the development of T2DM and its implications in pharmocogenetics and personalized medicine.
Lin, Gen-Min; Li, Yi-Hwei; Yin, Wei-Hsian; Wu, Yen-Wen; Chu, Pao-Hsien; Wu, Chih-Cheng; Hsu, Chih-Hsin; Wen, Ming-Shien; Voon, Wen-Chol; Wang, Chun-Chieh; Yeh, San-Jou; Lin, Wei-Shiang
A global heart failure (HF) registry suggested that the inverse association between body mass index (BMI) and all-cause mortality differed by race, particularly stronger in Japanese patients at 1-year follow-up. Whether this finding was consistent across all East Asian populations was unknown. In a multicenter prospective study in Taiwan, we enrolled 1,301 patients hospitalized for systolic HF from 2013 to 2014 and followed up the mortality after their discharge for a median of 1-year period. Cox proportional hazard regression analyses were used to assess the association of BMI with all-cause mortality. The results showed that BMI was inversely associated with all-cause mortality (hazard ratio and 95% CI per 5-kg/m(2) increase: 0.75 [0.62 to 0.91]) after adjusting for demographics, traditional risk factors, HF severity, and medications at discharge. Subsequently, we sought previous studies regarding the BMI association with mortality for East Asian patients with HF from Medline, and a random-effect meta-analysis was performed by the inverse variance method. The meta-analysis including 7 previous eligible studies (3 for the Chinese and 4 for the Japanese cohorts) and the present one showed similar results that BMI was inversely associated with all-cause mortality (hazard ratio 0.65 [0.58 to 0.73], I(2) = 37%). In conclusion, our study in Taiwan and a collaborative meta-analysis confirmed a strong inverse BMI-mortality association consistently among East Asian patients with HF.
Yu, Peilong; Zhang, Lifeng; Zhong, Quanjia
This study reveals that the relationship between the western North Pacific Ocean (WNPO; 0-55°N, 100-165°E) and the East Asian summer monsoon (EASM) experiences a well-defined interdecadal change in the late 1980s and early 1990s. The EASM-related WNPO sea surface temperature anomaly (SSTA) pattern changes from the dipole pattern [WNPO dipole (WNPOD)] that develops over the period between 1968 and 1987 (P1) to a tripole pattern [WNPO tripole (WNPOT)] between 1991 and 2010 (P2). The positive (negative) phase of the WNPOD is characterized by warm (cold) SSTAs in the Japan Sea and Kuroshio-Oyashio Extension region, and cold (warm) SSTAs in the subtropical WNPO, whereas the positive (negative) phase of the WNPOT shows warming (cooling) in the Kuroshio Extension region (KER), and cooling (warming) in the south of Kamchatka Peninsula (SKP) and Philippine Sea (PS). During P1 (P2), the WNPOD (WNPOT) can be regarded as the first (second) leading mode of summer WNPO SST variability, and its positive phase is associated with a weakened WNPO subtropical high and thereby the deficient summer rainfall in the Yangtze River valley, together with a strong EASM, and vice versa. The change in the WNPO-EASM relationship may be caused by interdecadal changes in the relationship of the equatorial central Pacific (ECP) with the WNPO and EASM, and an increase in summer KER SST variability. During P2, because the ECP warming-induced cyclonic anomalies move northwestwards and intensify, summertime ECP warming is able to generate a strong EASM and significant cooling over the two poles of the WNPOT (SKP and PS). These strengthened impacts of the ECP on the WNPOT and EASM contribute to the strengthened WNPOT-EASM relationship during P2. In addition, summer KER SST variability increases between 1991 and 2010, and this may have enhanced the impact of the KER on the EASM during P2. These two factors probably cause the EASM-related WNPO SSTA pattern to change from the WNPOD in P1 to the WNPOT in
Noh, Young Min; Lee, Kwonho; Kim, Kwanchul; Shin, Sung-Kyun; Müller, Detlef; Shin, Dong Ho
We estimate the aerosol direct radiative forcing (ADRF) and heating rate profiles of mixed East Asian dust plumes in the solar wavelength region ranging from 0.25 to 4.0 μm using the Santa Barbara Discrete Ordinate Atmospheric Radiative Transfer (SBDART) code. Vertical profiles of aerosol extinction coefficients and single-scattering albedos (SSA) were derived from measurements with a multi-wavelength Raman lidar system. The data are used as input parameters for our radiative transfer calculations. We considered four cases of radiative forcing in SBDART: 1. dust, 2. pollution, 3. mixed dust plume and the use of vertical profiles of SSA, and 4. mixed dust plumes and the use of column-averaged values of SSA. In our sensitivity study we examined the influence of SSA and aerosol layer height on our results. The ADRF at the surface and in the atmosphere shows a small dependence on the specific shape of the aerosol extinction vertical profile and its light-absorption property for all four cases. In contrast, at the top of the atmosphere (TOA), the ADRF is largely affected by the vertical distribution of the aerosols extinction. This effect increases if the light-absorption capacity (decrease of SSA) of the aerosols increases. We find different radiative effects in situations in which two layers of aerosols had different light-absorption properties. The largest difference was observed at the TOA for an absorbing aerosol layer at high altitude in which we considered in one case the vertical profile of SSA and in another case the column-averaged SSA only. The ADRF at the TOA increases when the light-absorbing aerosol layer is located above 3 km altitude. The differences between height-resolved SSA, which can be obtained from lidar data, and total layer-mean SSA indicates that the use of a layer-mean SSA can be rather misleading as it can induce a large error in the calculation of the ADRF at the TOA, which in turn may cause errors in the vertical profiles of heating rates.
Anderson, J. R.; Hua, X.
While ocean deposition of East Asian dust is given significant emphasis as a source of biologically-active trace elements, iron in particular, dust events are episodic and highly seasonal. There is, however, a constant source of aerosol that is chemically similar to dust (albeit amorphous in structure rather than crystalline) in the ash particles emitted from many hundreds of coal-fired power plants that are sited along the entire coastal region of China and Korea. The emission controls on these facilities vary widely and, in even cases of state-of-the-art emission controls, the secondary release of ash can be significant. There are of course even more small industrial and household sources of coal combustion emissions, in most cases with little or no emissions controls. Ash from a modern coal-fired power facility in Korea has been examined chemically and morphologically with electron microscopic techniques. As is characteristic of all such facilities, two principal types of ash are present: (1) flyash, silicate glass spheres that are emitted with the smoke and removed by electrostatic precipitators; and (2) bottom ash, "clinkers" and noncombustible material sticking to the furnace walls that are mixed with water and ground after cooling, then removed as a slurry to a dumping area. In addition, iron sulfide (pyrite) is a common constituent of coal and provides both a source of sulfur dioxide gas and also molten iron spherical particles in the ash. The iron spheres then are rapidly oxidized upon cooling. Bottom ash is a more complex material than flyash in that it contains more iron and other trace metals, plus it contains varying amounts of uncombusted carbon. The post-combustion handling of bottom ash can lead to significant emissions despite the fact that little or none goes out the stack. The iron oxide spheres can also be emitted by this secondary method. The concentrations of ash can be very high in close proximity to power plants (PM10 of several hundred
Nemitz, E.; Misztal, P.; Langford, B.; Oram, D.; Phillips, G.; di Marco, C.; Davison, B.; Hewitt, N.; Cape, N.
Fluxes of volatile organic compounds were measured above tropical rainforest and oil palm plantation in the Malaysian state of Sabah on the island of Borneo. During April and July 2008 an Ionikon proton transfer reaction mass spectrometer (ptrms) was operated at the 100 m Global Atmospheric Watch (GAW) tower at Bukit Atur, at the edge of the Danum Valley conservation area. An ultrasonic anemometer and air inlet were mounted at 76 m, with the ptrms housed in a laboratory building at the foot of the tower, measuring fluxes over tropical rainforest (selectively logged in 1989) with a typical canopy height of 30 to 40 m. In addition, during the July period, a second ptrms was coupled to a lift system which automatically moved an inlet to sample in-canopy gradients inside the forest canopy, between 2 and 30 m. During May 2008, the ptrms was moved to an oil palm plantation, north of the town of Lahad Datu, were fluxes were measured at a height of 15 m above the 12 m tall canopy, together with concentrations and fluxes of ozone and aerosols. These measurements formed part of two major UK projects: OP3-Danum-2008 (Oxidant and Particle Production Processes above South East Asian Rainforest) was aimed at quantifying biogenic emissions and evaluating their impact on air chemistry and the production of photo-oxidants and biogenic secondary organic aerosol, while ACES (Aerosol Coupling in the Earth System) studies the role of primary biogenic emissions, in-canopy processes and the effect of land-use change on aerosols. Initial results indicate that fluxes of isoprene above forest averaged 1.4 mg m-2 s-1 which is somewhat smaller than previous measurements in Amazonia and than previous estimates derived from leaf- level measurements, reflecting uncertainties in the assumed plant species composition. Concentrations peaked at the top of the canopy during midday. With an average of 5.5 mg m-2s-1, isoprene fluxes above the oil palm plantation were four times larger. Average fluxes
Hardelid, P; Cortina-Borja, M; Munro, A; Jones, H; Cleary, M; Champion, M P; Foo, Y; Scriver, C R; Dezateux, C
Phenylketonuria (PKU) is an autosomal recessive inborn error of metabolism (OMIM 261600). Treatment with a low-phenylalanine diet following early ascertainment by newborn screening prevents impaired cognitive development, the major disease phenotype in PKU. The overall birth prevalence of PKU in European, Chinese and Korean populations is approximately 1/10,000. Since the human PAH locus contains PKU-causing alleles and polymorphic core haplotypes that describe and corroborate an out-of-Africa range expansion in modern human populations, it is of interest to know the prevalence of PKU in different ethnic groups with diverse geographical origin. We estimated PKU prevalence in South East England, where a sizeable proportion of the population are of Sub-Saharan African or South Asian ancestry. Over the period 1994 to 2004 167 children were diagnosed with PKU. Using birth registration and census data to derive denominators, PKU birth prevalence per 10,000 live births (95% Bayesian credible intervals) was estimated to be 1.14 (0.96-1.33) among white, 0.11 (0.02-0.37) among black, and 0.29 (0.10-0.63) among Asian ethnic groups. This suggests that PKU is up to an order of magnitude less prevalent in populations with Sub-Saharan African and South Asian ancestry that have migrated to the UK.
Park, H; Shaukat, S; Liu, X; Hahn, S; Naz, S; Ghosh, M; Kim, H; Moon, S; Abe, S; Tukamoto, K; Riazuddin, S; Kabra, M; Erdenetungalag, R; Radnaabazar, J; Khan, S; Pandya, A; Usami, S; Nance, W; Wilcox, E; Riazuddin, S; Griffith, A
Recessive mutations of SLC26A4 (PDS) are a common cause of Pendred syndrome and non-syndromic deafness in western populations. Although south and east Asia contain nearly one half of the global population, the origins and frequencies of SLC26A4 mutations in these regions are unknown. We PCR amplified and sequenced seven exons of SLC26A4 to detect selected mutations in 274 deaf probands from Korea, China, and Mongolia. A total of nine different mutations of SLC26A4 were detected among 15 (5.5%) of the 274 probands. Five mutations were novel and the other four had seldom, if ever, been identified outside east Asia. To identify mutations in south Asians, 212 Pakistani and 106 Indian families with three or more affected offspring of consanguineous matings were analysed for cosegregation of recessive deafness with short tandem repeat markers linked to SLC26A4. All 21 SLC26A4 exons were PCR amplified and sequenced in families segregating SLC26A4 linked deafness. Eleven mutant alleles of SLC26A4 were identified among 17 (5.4%) of the 318 families, and all 11 alleles were novel. SLC26A4 linked haplotypes on chromosomes with recurrent mutations were consistent with founder effects. Our observation of a diverse allelic series unique to each ethnic group indicates that mutational events at SLC26A4 are common and account for approximately 5% of recessive deafness in south Asians and other populations. PMID:12676893
Gai, N; Pan, J; Yin, X C; Zhu, X H; Yu, H Q; Li, Y; Tan, K Y; Jiao, X C; Yang, Y L
Activities of atmospheric aerosols, bulk deposition fluxes, and undisturbed soil inventories of (7)Be were investigated in China's East Asian monsoon zone at various latitudes ranging from 23.8°N to 43.5°N. The annual latitudinal distributions of (7)Be concentrations in aerosols follow a distribution pattern which looks similar to a normal distribution with the maxima occurring in the mid-latitude region. Simultaneous measurements of (7)Be at various latitudes suggest that atmospheric circulation may play an important role in the latitudinal distributions of (7)Be in surface air. Latitude and wet precipitation are the main factors controlling the bulk (7)Be depositional fluxes. Significant seasonal variations in (7)Be depositional fluxes in Beijing, a mid-latitude city, were observed with the highest flux in summer and the lowest in winter, whereas less seasonality were found in the high- and the low-latitude cities. The highest (7)Be inventory in undisturbed soils in summer also occurred at a mid-latitudinal area in the East Asian monsoon zone. Precipitation is the main factor controlling the (7)Be soil inventory in Qingdao with the highest values occurring in autumn followed by summer.
Benitez-Garcia, Gibran; Nakamura, Tomoaki; Kaneko, Masahide
Darwin was the first one to assert that facial expressions are innate and universal, which are recognized across all cultures. However, recent some cross-cultural studies have questioned this assumed universality. Therefore, this paper presents an analysis of the differences between Western and East-Asian faces of the six basic expressions (anger, disgust, fear, happiness, sadness and surprise) focused on three individual facial regions of eyes-eyebrows, nose and mouth. The analysis is conducted by applying PCA for two feature extraction methods: appearance-based by using the pixel intensities of facial parts, and geometric-based by handling 125 feature points from the face. Both methods are evaluated using 4 standard databases for both racial groups and the results are compared with a cross-cultural human study applied to 20 participants. Our analysis reveals that differences between Westerns and East-Asians exist mainly on the regions of eyes-eyebrows and mouth for expressions of fear and disgust respectively. This work presents important findings for a better design of automatic facial expression recognition systems based on the difference between two racial groups.
Hsu, S.-C.; Gong, G.-C.; Shiah, F.-K.; Hung, C.-C.; Kao, S.-J.; Zhang, R.; Chen, W.-N.; Chen, C.-C.; Chou, C. C.-K.; Lin, Y.-C.; Lin, F.-J.; Lin, S.-H.
Iron and phosphorous are essential to marine microorganisms in vast regions in oceans worldwide. Atmospheric inputs are important allochthonous sources of Fe and P. The variability in airborne Fe deposition is hypothesized to serve an important function in previous glacial-interglacial cycles, contributing to the variability in atmospheric CO2 and ultimately the climate. Understanding the mechanisms underlying the mobilization of airborne Fe and P from insoluble to soluble forms is critical to evaluate the biogeochemical effects of these elements. In this study, we present a robust power-law correlation between fractional Fe solubility and non-sea-salt-sulfate / Total-Fe (nss-sulfate / FeT) molar ratio independent of distinct sources of airborne Fe of natural and/or anthropogenic origins over the South China Sea. This area receives Asian dust and pollution outflows and Southeast Asian biomass burning. This correlation is also valid for nitrate and total acids, demonstrating the significance of acid processing in enhancing Fe mobilization. Such correlations are also found for P, yet source dependent. These relationships serve as straightforward parameters that can be directly incorporated into available atmosphere-ocean coupling models that facilitate the assessment of Fe and P fertilization effects. Although biomass burning activity may supply Fe to the bioavailable Fe pool, pyrogenic soils are possibly the main contributors, not the burned plants. This finding warrants a multidisciplinary investigation that integrates atmospheric observations with the resulting biogeochemistry in the South China Sea, which is influenced by atmospheric forcings and nutrient dynamics with monsoons.
Konecky, B. L.; Russell, J. M.; Vogel, H.; Bijaksana, S.; Huang, Y.
The Indo-Pacific Warm Pool (IPWP) invigorates the oceanic-atmospheric circulation in the tropics, with far-reaching climate impacts that extend into the high latitudes. A growing number of deglacial proxy reconstructions from the Maritime Continent and its surrounding seas have revealed the importance of both high- and low-latitude climate processes to IPWP rainfall during the deglaciation and the Holocene. However, few records extend beyond the Last Glacial Maximum (LGM), making it difficult to assess regional rainfall characteristics and monsoon interactions under the glacial/interglacial boundary conditions of the Pleistocene. Proxy reconstructions of the oxygen and hydrogen isotopic composition of rainfall (δ18O/δDprecip) have proven useful in understanding millennial to orbital scale changes in the climate of the Maritime Continent, but the tendency for δ18O/δDprecip in this region to reflect regional and/or remote climate p