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Sample records for ecg-triggered axial ct

  1. An automatic machine learning system for coronary calcium scoring in clinical non-contrast enhanced, ECG-triggered cardiac CT

    NASA Astrophysics Data System (ADS)

    Wolterink, Jelmer M.; Leiner, Tim; Takx, Richard A. P.; Viergever, Max A.; Išgum, Ivana

    2014-03-01

    Presence of coronary artery calcium (CAC) is a strong and independent predictor of cardiovascular events. We present a system using a forest of extremely randomized trees to automatically identify and quantify CAC in routinely acquired cardiac non-contrast enhanced CT. Candidate lesions the system could not label with high certainty were automatically identified and presented to an expert who could relabel them to achieve high scoring accuracy with minimal effort. The study included 200 consecutive non-contrast enhanced ECG-triggered cardiac CTs (120 kV, 55 mAs, 3 mm section thickness). Expert CAC annotations made as part of the clinical routine served as the reference standard. CAC candidates were extracted by thresholding (130 HU) and 3-D connected component analysis. They were described by shape, intensity and spatial features calculated using multi-atlas segmentation of coronary artery centerlines from ten CTA scans. CAC was identified using a randomized decision tree ensemble classifier in a ten-fold stratified cross-validation experiment and quantified in Agatston and volume scores for each patient. After classification, candidates with posterior probability indicating uncertain labeling were selected for further assessment by an expert. Images with metal implants were excluded. In the remaining 164 images, Spearman's p between automatic and reference scores was 0.94 for both Agatston and volume scores. On average 1.8 candidate lesions per scan were subsequently presented to an expert. After correction, Spearman's p was 0.98. We have described a system for automatic CAC scoring in cardiac CT images which is able to effectively select difficult examinations for further refinement by an expert.

  2. Effect of Heart Rate and Body Mass Index on the Interscan and Interobserver Variability of Coronary Artery Calcium Scoring at Prospective ECG-Triggered 64-Slice CT

    PubMed Central

    Matsuura, Noriaki; Yamamoto, Hideya; Kiguchi, Masao; Fujioka, Chikako; Kitagawa, Toshiro; Ito, Katsuhide

    2009-01-01

    Objective To test the effects of heart rate, body mass index (BMI) and noise level on interscan and interobserver variability of coronary artery calcium (CAC) scoring on a prospective electrocardiogram (ECG)-triggered 64-slice CT. Materials and Methods One hundred and ten patients (76 patients with CAC) were scanned twice on prospective ECG-triggered scans. The scan parameters included 120 kV, 82 mAs, a 2.5 mm thickness, and an acquisition center at 45% of the RR interval. The interscan and interobserver variability on the CAC scores (Agatston, volume, and mass) was calculated. The factors affecting the variability were determined by plotting it against heart rate, BMI, and noise level (defined as the standard deviation: SD). Results The estimated effective dose was 1.5 ± 0.2 mSv. The mean heart rate was 63 ± 12 bpm (range, 44-101 bpm). The patient BMIs were 24.5 ± 4.5 kg/m2 (range, 15.5-42.3 kg/m2). The mean and median interscan variabilities were 11% and 6%, respectively by volume, and 11% and 6%, respectively, by mass. Moreover, the mean and median of the algorithms were lower than the Agatston algorithm (16% and 9%, respectively). The mean and median interobserver variability was 10% and 4%, respectively (average of algorithms). The mean noise levels were 15 ± 4 Hounsfield unit (HU) (range, 8-25 HU). The interscan and interobserver variability was not correlated with heart rate, BMI, or noise level. Conclusion The interscan and interobserver variability of CAC on a prospective ECG-triggered 64-slice CT with high image quality and 45% of RR acquisition is not significantly affected by heart rate, BMI, or noise level. The volume or mass algorithms show reduced interscan variability compared to the Agatston scoring (p < 0.05). PMID:19568461

  3. Diagnostic accuracy of sub-mSv prospective ECG-triggering cardiac CT in young infant with complex congenital heart disease.

    PubMed

    Gao, Wei; Zhong, Yu Min; Sun, Ai Min; Wang, Qian; Ouyang, Rong Zhen; Hu, Li Wei; Qiu, Han Sheng; Wang, Shi Yu; Li, Jian Ying

    2016-06-01

    To explore the clinical value and evaluate the diagnostic accuracy of sub-mSv low-dose prospective ECG-triggering cardiac CT (CCT) in young infants with complex congenital heart disease (CHD). A total of 102 consecutive infant patients (53 boys and 49 girls with mean age of 2.9 ± 2.4 m and weight less than 5 kg) with complex CHD were prospectively enrolled. Scans were performed on a 64-slice high definition CT scanner with low dose prospective ECG-triggering mode and reconstructed with 80 % adaptive statistical iterative reconstruction algorithm. All studies were performed during free breathing with sedation. The subjective image quality was evaluated by 5-point grading scale and interobserver variability was calculated. The objective image noise (standard deviation, SD) and contrast to noise ratio (CNR) was calculated. The effective radiation dose from the prospective ECG-triggering mode was recorded and compared with the virtual conventional retrospective ECG-gating mode. The detection rate for the origin of coronary artery was calculated. All patients also underwent echocardiography before CCT examination. 81 patients had surgery and their preoperative CCT and echocardiography findings were compared with the surgical results and sensitivity, specificity, positive and negative predictive values and accuracy were calculated for separate cardiovascular anomalies. Heart rates were 70-161 beats per minute (bpm) with mean value of 129.19 ± 14.52 bpm. The effective dose of 0.53 ± 0.15 mSv in the prospective ECG-triggering cardiac CT was lower than the calculated value in a conventional retrospective ECG-gating mode (2.00 ± 0.35 mSv) (p < 0.001). The mean CNR and SD were 28.19 ± 13.00 and 15.75 ± 3.61HU, respectively. The image quality scores were 4.31 ± 0.36 and 4.29 ± 0.41 from reviewer 1 and 2 respectively with an excellent agreement between them (Kappa = 0.85). The detection rate for the origins of the left and right coronary

  4. Improvement of Image Quality and Diagnostic Performance by an Innovative Motion-Correction Algorithm for Prospectively ECG Triggered Coronary CT Angiography

    PubMed Central

    Lu, Bin; Yan, Hong-Bing; Mu, Chao-Wei; Gao, Yang; Hou, Zhi-Hui; Wang, Zhi-Qiang; Liu, Kun; Parinella, Ashley H.; Leipsic, Jonathon A.

    2015-01-01

    Objective To investigate the effect of a novel motion-correction algorithm (Snap-short Freeze, SSF) on image quality and diagnostic accuracy in patients undergoing prospectively ECG-triggered CCTA without administering rate-lowering medications. Materials and Methods Forty-six consecutive patients suspected of CAD prospectively underwent CCTA using prospective ECG-triggering without rate control and invasive coronary angiography (ICA). Image quality, interpretability, and diagnostic performance of SSF were compared with conventional multisegment reconstruction without SSF, using ICA as the reference standard. Results All subjects (35 men, 57.6 ± 8.9 years) successfully underwent ICA and CCTA. Mean heart rate was 68.8±8.4 (range: 50–88 beats/min) beats/min without rate controlling medications during CT scanning. Overall median image quality score (graded 1–4) was significantly increased from 3.0 to 4.0 by the new algorithm in comparison to conventional reconstruction. Overall interpretability was significantly improved, with a significant reduction in the number of non-diagnostic segments (690 of 694, 99.4% vs 659 of 694, 94.9%; P<0.001). However, only the right coronary artery (RCA) showed a statistically significant difference (45 of 46, 97.8% vs 35 of 46, 76.1%; P = 0.004) on a per-vessel basis in this regard. Diagnostic accuracy for detecting ≥50% stenosis was improved using the motion-correction algorithm on per-vessel [96.2% (177/184) vs 87.0% (160/184); P = 0.002] and per-segment [96.1% (667/694) vs 86.6% (601/694); P <0.001] levels, but there was not a statistically significant improvement on a per-patient level [97.8 (45/46) vs 89.1 (41/46); P = 0.203]. By artery analysis, diagnostic accuracy was improved only for the RCA [97.8% (45/46) vs 78.3% (36/46); P = 0.007]. Conclusion The intracycle motion correction algorithm significantly improved image quality and diagnostic interpretability in patients undergoing CCTA with prospective ECG triggering and

  5. Body physique and heart rate variability determine the occurrence of stair-step artefacts in 64-slice CT coronary angiography with prospective ECG-triggering.

    PubMed

    Husmann, Lars; Herzog, Bernhard A; Burkhard, Nina; Tatsugami, Fuminari; Valenta, Ines; Gaemperli, Oliver; Wyss, Christophe A; Landmesser, Ulf; Kaufmann, Philipp A

    2009-07-01

    The purpose of this study was to describe and characterize the frequency and extent of stair-step artefacts in computed tomography coronary angiography (CTCA) with prospective electrocardiogram (ECG)-triggering and to identify their determinants. One hundred and forty three consecutive patients (55 women, mean age 57 +/- 13 years) underwent 64-slice CTCA using prospective ECG-triggering. Occurrence of stair-step artefacts in CTCA of the thoracic wall and the coronary arteries was determined and maximum offset was measured. If stair-step artefacts occurred in both cases, a difference between thoracic wall and coronary artery offset of 0.6 mm or greater was attributed to additional motion of the heart. Mean effective radiation dose was 2.1 +/- 0.7 mSv (range 1.0-3.5 mSv). Eighty-nine patients (62%) had stair-step artefacts in CTCA of the coronary arteries (mean offset of 1.7 +/- 1.1 mm), while only 77 patients had thoracic wall stair-step artefacts (mean offset of 1.0 +/- 0.3 mm; significantly different, P < 0.001). Stair-step artefacts in CTCA of the thoracic wall were determined by BMI and weight (P < 0.01), while artefacts in CTCA of the coronary arteries were associated with heart rate variability (P < 0.05). Stair-step artefacts in CTCA with prospective ECG-triggering are determined by (a) motion of the entire patient during table travel, particularly in large patients and (b) by motion of the heart, particularly when heart rates are variable.

  6. Evaluation of superior vena cava syndrome by axial CT and CT phlebography

    SciTech Connect

    Moncada, R.; Cardella, R.; Demos, T.C.; Churchill, R.J.; Cardoso, M.; Love, L.; Reynes, C.J.

    1984-10-01

    Transverse axial computed tomography (CT) has been combined with CT digital phlebography to study nine patients with superior vena cava syndrome. Six were due to malignancy, two were secondary to benign disease, and one was a paraneoplastic manifestation. This combined CT approach successfully identified the abnormal morphology of the superior vena cava, demonstrating external compression, encasement, or intraluminal thrombus in all patients and the collateral venous channels in eight. This technique is a rapid, informative, and cost-effective method for the workup of superior vena cava syndrome. The CT digital phlebogram, however, is not successful in regularly and optimally opacifying the normal superior vena cava because of the limited amount of contrast material, dilution effect of the nonopacified incoming flow from the jugular and azygos veins, and the lack of image enhancement from the CT digital scanograms.

  7. Whole-Chest 64-MDCT of Emergency Department Patients with Nonspecific Chest Pain: Radiation Dose and Coronary Artery Image Quality with Prospective ECG Triggering Versus Retrospective ECG Gating

    PubMed Central

    Shuman, William P.; Branch, Kelley R.; May, Janet M.; Mitsumori, Lee M.; Strote, Jared N.; Warren, Bill H.; Dubinsky, Theodore J.; Lockhart, David W.; Caldwell, James H.

    2012-01-01

    Objective The purpose of this study was to compare the patient radiation dose and coronary artery image quality of long-z-axis whole-chest 64-MDCT performed with retrospective ECG gating with those of CT performed with prospective ECG triggering in the evaluation of emergency department patients with nonspecific chest pain. Subjects and Methods Consecutively registered emergency department patients with nonspecific low-to-moderate-risk chest pain underwent whole-chest CT with retrospective gating (n = 41) or prospective triggering (n = 31). Effective patient radiation doses were estimated and compared by use of unpaired Student's t tests. Two reviewers independently scored the quality of images of the coronary arteries, and the scores were compared by use of ordinal logistic regression. Results Age, heart rate, body mass index, and z-axis coverage were not statistically different between the two groups. For retrospective gating, the mean effective radiation dose was 31.8 ± 5.1 mSv; for prospective triggering, the mean effective radiation dose was 9.2 ± 2.2 mSv (prospective triggering 71% lower, p < 0.001). Two of 512 segments imaged with retrospective gating were nonevaluable (0.4%), and two of 394 segments imaged with prospective triggering were nonevaluable (0.5%). Prospectively triggered images were 2.2 (95% CI, 1.1–4.5) times as likely as retrospectively gated images to receive a high image quality score for each segment after adjustment for segment differences (p < 0.05). Conclusion For long-z-axis whole-chest 64-MDCT of emergency department patients with nonspecific chest pain, use of prospective ECG triggering may result in substantially lower patient radiation doses and better coronary artery image quality than is achieved with retrospective ECG gating. PMID:19457832

  8. Pediatric organ dose measurements in axial and helical multislice CT

    SciTech Connect

    McDermott, Alanna; White, R. Allen; Mc-Nitt-Gray, Mike; Angel, Erin; Cody, Dianna

    2009-05-15

    An anthropomorphic pediatric phantom (5-yr-old equivalent) was used to determine organ doses at specific surface and internal locations resulting from computed tomography (CT) scans. This phantom contains four different tissue-equivalent materials: Soft tissue, bone, brain, and lung. It was imaged on a 64-channel CT scanner with three head protocols (one contiguous axial scan and two helical scans [pitch=0.516 and 0.984]) and four chest protocols (one contiguous axial scan and three helical scans [pitch=0.516, 0.984, and 1.375]). Effective mA s [=(tube currentxrotation time)/pitch] was kept nearly constant at 200 effective mA s for head and 290 effective mA s for chest protocols. Dose measurements were acquired using thermoluminescent dosimeter powder in capsules placed at locations internal to the phantom and on the phantom surface. The organs of interest were the brain, both eyes, thyroid, sternum, both breasts, and both lungs. The organ dose measurements from helical scans were lower than for contiguous axial scans by 0% to 25% even after adjusting for equivalent effective mA s. There was no significant difference (p>0.05) in organ dose values between the 0.516 and 0.984 pitch values for both head and chest scans. The chest organ dose measurements obtained at a pitch of 1.375 were significantly higher than the dose values obtained at the other helical pitches used for chest scans (p<0.05). This difference was attributed to the automatic selection of the large focal spot due to a higher tube current value. These findings suggest that there may be a previously unsuspected radiation dose benefit associated with the use of helical scan mode during computed tomography scanning.

  9. Can nontriggered thoracic CT be used for coronary artery calcium scoring? A phantom study

    SciTech Connect

    Xie, Xueqian; Greuter, Marcel J. W.; Groen, Jaap M.; Bock, Geertruida H. de; Oudkerk, Matthijs; Jong, Pim A. de; Vliegenthart, Rozemarijn

    2013-08-15

    Purpose: Coronary artery calcium score, traditionally based on electrocardiography (ECG)-triggered computed tomography (CT), predicts cardiovascular risk. However, nontriggered CT is extensively utilized. The study-purpose is to evaluate the in vitro agreement in coronary calcium score between nontriggered thoracic CT and ECG-triggered cardiac CT.Methods: Three artificial coronary arteries containing calcifications of different densities (high, medium, and low), and sizes (large, medium, and small), were studied in a moving cardiac phantom. Two 64-detector CT systems were used. The phantom moved at 0–90 mm/s in nontriggered low-dose CT as index test, and at 0–30 mm/s in ECG-triggered CT as reference. Differences in calcium scores between nontriggered and ECG-triggered CT were analyzed by t-test and 95% confidence interval. The sensitivity to detect calcification was calculated as the percentage of positive calcium scores.Results: Overall, calcium scores in nontriggered CT were not significantly different to those in ECG-triggered CT (p > 0.05). Calcium scores in nontriggered CT were within the 95% confidence interval of calcium scores in ECG-triggered CT, except predominantly at higher velocities (≥50 mm/s) for the high-density and large-size calcifications. The sensitivity for a nonzero calcium score was 100% for large calcifications, but 46%± 11% for small calcifications in nontriggered CT.Conclusions: When performing multiple measurements, good agreement in positive calcium scores is found between nontriggered thoracic and ECG-triggered cardiac CT. Agreement decreases with increasing coronary velocity. From this phantom study, it can be concluded that a high calcium score can be detected by nontriggered CT, and thus, that nontriggered CT likely can identify individuals at high risk of cardiovascular disease. On the other hand, a zero calcium score in nontriggered CT does not reliably exclude coronary calcification.

  10. Comparing the diagnostic utility of sacroiliac spectral CT and MRI in axial spondyloarthritis

    PubMed Central

    Zhang, Ping; Yu, Kai Hu; Guo, Rui Min; Ran, Jun; Liu, Yao; Morelli, John; Runge, Val A

    2016-01-01

    Objective: To compare the clinical value of sacroiliac spectral CT and MRI in diagnosing axial spondyloarthritis (SpA). Methods: 137 patients with low back pain and suspected axial SpA were recruited. 76 patients were diagnosed with axial SpA, and 49 patients were diagnosed with non-specific low back pain (nLBP). Each patient underwent spectral CT and MRI examinations of the sacroiliac joints. Water- and calcium-based material decomposition images were reconstructed for quantitative analysis. The marrow-to-muscle ratios of water and calcium concentrations and short tau inversion recovery (STIR) signal intensity, as well as Hounsfield units in the ilium and sacrum were compared between nLBP and patients with axial SpA. Results: Spectral CT is comparable with MRI for the detection of bone marrow oedema, and it is superior to MRI for detection of osseous sclerosis and erosions. MRI is superior to spectral CT in detecting enthesitis and synovitis. There were statistically significant differences in STIR signal intensity, water concentration and calcium concentration ratios as well as CT values between nLBP and patients with axial SpA (p < 0.05) in the ilium. There was a statistically significant but weak correlation between ratios of water concentration and STIR signal intensity in both the ilium and sacrum (p < 0.05). Overall, the iliac water concentration was most sensitive for detection of patients with SpA. The positive likelihood ratio of the STIR signal intensity ratio was the highest. The diagnostic odds ratio of the calcium concentration ratio was the highest, and its negative likelihood ratio was the lowest. Conclusion: Spectral CT not only depicts findings of chronic sacroiliitis (i.e. bone erosion and sclerosis), but also can detect and quantify the extent of marrow oedema in patients with SpA with activity sacroiliitis. The sensitivity of MRI for diagnosis of early synovitis and enthesitis remains superior. The combination of spectral CT and MRI may

  11. Computed tomography coronary angiography with a consistent dose below 2 mSv using double prospectively ECG-triggered high-pitch spiral acquisition in patients with atrial fibrillation: initial experience.

    PubMed

    Wang, Qi; Qin, Jing; He, Bai; Zhou, Yin; Yang, Jun-jie; Hou, Xiao-ling; Yang, Xiao-bo; Chen, Jiu-hong; Chen, Yun-dai

    2013-08-01

    To evaluate the feasibility and imaging quality of double prospectively ECG-triggered high-pitch spiral acquisition mode (double flash mode) for coronary computed tomography angiography (CTCA) in patients with atrial fibrillation (AF). 47 patients (11 women, 36 men; mean age 64.5 ± 12.1 years) were enrolled for CTCA examinations using a dual-source CT with 2 × 128 × 0.6 mm collimation, 0.28 s rotation time and a pitch of 3.4. Double flash mode was prospectively triggered first at 60 % and later at 30 % of the R-R interval within two cardiac cycles. Image quality was evaluated using a four-point scale (1 = excellent, 4 = non-assessable). From 672 coronary artery segments, 77.5 % (521/672) was rated as score of 1, 20.8 % (140/672) as score of 2, 1.2 % (8/672) as score of 3 and 0.4 % (3/672) was rated as 'non-assessable'. The average image quality score was 1.25 ± 0.38 on a per segment basis. Mean dose-length product for CTCA was 92.6 ± 28.2 mGy cm, the effective dose was 1.30 ± 0.39 mSv (0.64-1.97 mSv). In patients with AF, double prospectively ECG-triggered high-pitch spiral acquisition mode could be a feasible and valuable scan mode for CTCA with a consistent dose below 2 mSv as well as diagnostic imaging quality.

  12. Locating the reference point of symphysis pubis in axial CT images.

    PubMed

    Oh, Jiyong; Jung, Dae Chul; Choi, Chong-Ho

    2012-02-01

    In this paper, we present an effective method to determine the reference point of symphysis pubis (SP) in an axial stack of CT images to facilitate image registration for pelvic cancer treatment. In order to reduce the computational time, the proposed method consists of two detection parts, the coarse detector, and the fine detector. The detectors check each image patch whether it contains the characteristic structure of SP. The coarse detector roughly determines the location of the reference point of SP using three types of information, which are the location and intensity of an image patch, the SP appearance, and the geometrical structure of SP. The fine detector examines around the location found by the coarse detection to refine the location of the reference point of SP. In the experiment, the average location error of the propose method was 2.23 mm, which was about the side length of two pixels. Considering that the average location error by a radiologist is 0.77 mm, the proposed method finds the reference point quite accurately. Since it takes about 10 s to locate the reference point from a stack of CT images, it is fast enough to use in real time to facilitate image registration of CT images for pelvic cancer treatment.

  13. Reformatted images improve the detection rate of acute traumatic subdural hematomas on brain CT compared with axial images alone.

    PubMed

    Amrhein, Timothy J; Mostertz, William; Matheus, Maria Gisele; Maass-Bolles, Genevieve; Sharma, Komal; Collins, Heather R; Kranz, Peter G

    2017-02-01

    Subdural hematomas (SDHs) comprise a significant percentage of missed intracranial hemorrhage on axial brain CT. SDH detection rates could be improved with the addition of reformatted images. Though performed at some centers, the potential additional diagnostic sensitivity of reformatted images has not yet been investigated. The purpose of our study is to determine if the addition of coronal and sagittal reformatted images to an axial brain CT increases the sensitivity and specificity for detection of acute traumatic SDH. We retrospectively reviewed consecutive brain CTs acquired for acute trauma that contained new SDHs. An equivalent number of normal brain CTs served as control. Paired sets of images were created for each case: (1) axial images only ("axial only") and (2) axial, coronal, sagittal images ("reformat added"). Three readers interpreted both the axial only and companion reformat added for each case, separated by 1 month. Reading times and SDH detection rates were compared. One hundred SDH and 100 negative examinations were collected. Sensitivity and specificity for the axial-only scans were 75.7 and 94.3 %, respectively, compared with 88.3 and 98.3 % for reformat added. There was a 24.3 % false negative (missed SDH) rate with axial-only scans versus 11.7 % with reformat added (p = <0.001). Median reader interpretation times were longer with the addition of reformatted images (125 versus 89 s), but this difference was not significant (p = 0.23). The addition of coronal and sagittal images in trauma brain CT resulted in improved sensitivity and specificity as well as a reduction in SDH false negatives by greater than 50 %. Reformatted images substantially reduce the number of missed SDHs compared with axial images alone.

  14. Assessments of Coronary Artery Visibility and Radiation Dose in Infants with Congenital Heart Disease on Cardiac 128-slice CT and on Cardiac 64-slice CT.

    PubMed

    Cui, Y; Huang, M; Zheng, J; Li, J; Liu, H; Liang, C

    2016-01-01

    The aim of this study was to compare the coronary artery visibility and radiation dose in infants with CHD on cardiac 128-slice CT and on cardiac 64-slice CT. The images of 200 patients were analyzed in this study, 100 patients were selected randomly from a group of 789 infants (<1 years old) with CHD undergoing 128-slice CT prospective ECG-triggered axial scan, and 100 were selected randomly from 911 infants with CHD undergoing 64-slice CT retrospective ECG-gated spiral scan. The visibility of coronary artery segments was graded on a four-point scale. The coronary arteries were considered to be detected or visible when grade was 2 or higher. The visibility of the coronary artery segments and the radiation dose was compared between the two groups. Except for the rate of LM (96 vs. 99%), the detection rates of the total, LAD, LCX, RCA, and the proximal segment of the RCA in the 256-slice CT group were significantly higher than those in the 64-slice CT group (51.7, 53.33, 33.67, 53.33, and 99 vs. 34.8, 34.33, 18, 30.67, and 75%, respectively). The counts of visibility score (4/3/2/1) for the LM and the proximal segment of the RCA were 62/22/12/4 and 56/20/17/7, respectively, in the 128-slice CT group and 17/42/30/1 and 9/30/38/25, respectively, in the 64-slice CT group. There were significant differences, especially for score 4 and 3, between the two groups. The radiation dose in the 128-slice CT group was significantly decreased than those in the 64-slice CT group (CTDIvol 1.88 ± 0.51 vs. 5.61 ± 0.63 mGy; SSDE 4.48 ± 1.15 vs. 13.97 ± 1.52 mGy; effective radiation dose 1.36 ± 0.44 vs. 4.06 ± 0.7 mSv). With reduced radiation dose, the visibility of the coronary artery in infants with CHD via prospective ECG-triggered mode on a 128-slice CT is superior to that of the 64-slice CT using retrospective ECG-gated spiral mode.

  15. A framework for automated coronary artery tracking of low axial resolution multi slice CT images

    NASA Astrophysics Data System (ADS)

    Wu, Jing; Ferns, Gordon; Giles, John; Lewis, Emma

    2011-03-01

    Low axial resolution data such as multi-slice CT(MSCT) used for coronary artery disease screening must balance the potential loss in image clarity, detail and partial volume effects with the benefits to the patient such as faster acquisition time leading to lower dose exposure. In addition, tracking of the coronary arteries can aid the location of objects contained within, thus helping to differentiate them from similar in appearance, difficult to discern neighbouring regions. A fully automated system has been developed to segment and track the main coronary arteries and visualize the results. Automated heart isolation is carried out for each slice of an MSCT image using active contour methods. Ascending aorta and artery root segmentation is performed using a combination of active contours, morphological operators and geometric analysis of coronary anatomy to identify a starting point for vessel tracking. Artery tracking and backtracking employs analysis of vessel position combined with segmented region shape analysis to obtain artery paths. Robust, accurate threshold parameters are calculated for segmentation utilizing Gaussian Mixture Model fitting and analysis. The low axial resolution of our MSCT data sets, in combination with poor image clarity and noise presented the greatest challenge. Classification techniques such as shape analysis have been utilized to good effect and our results to date have shown that such deficiencies in the data can be overcome, further promoting the positive benefits to patients.

  16. The evaluation and comparison of kidney length obtained from axial cuts in spiral CT scan with its true length

    PubMed Central

    Karami, Mehdi; Rahimi, Farshad; Tajadini, Mohammadhasan

    2015-01-01

    Background: Increased size of kidney is the main symptom of pyelonephritis and renal ischemia in children. Ultrasound and computed tomography (CT) scan methods are the imaging methods for evaluating the urogenital system. The aim of this study is to compare the kidney length obtained from spiral CT scan with the true length obtained from multi-slice CT. Materials and Methods: From 100 patients 200 kidneys were examined in Alzahra Hospital in 2012. Multi-slice CT was used to obtain coronal and sagittal cuts to find the length of kidneys. Results: The mean values of true size of axial sections of the right and left kidneys were 108.37 ± 12.3 mm and 109.74 ± 13.6 mm, respectively. The mean difference of axial sections’ lengths in the right and left kidneys was 1.37 ± 1.22 mm. The mean values of length in the spiral CT scan of the right and left kidneys were 98.61 ± 15.8 mm and 103.11 ± 15.9 mm, respectively. The difference in the estimated size by multi-slice CT scan in oblique and axial images was significant (9.77 ± 1.19 mm and 6.63 ± 0.8 mm for the right and left kidneys, respectively (P < 0.001). Conclusion: The average size of both kidneys determined in axial images was smaller than the actual size. The estimation of kidney size in axial images is not reliable, and to obtain the actual size, it is required to have the coronal and sagittal cuts with proper quality, which could be achieved by multi-slice method. PMID:25709984

  17. Maximum Diameter Measurements of Aortic Aneurysms on Axial CT Images After Endovascular Aneurysm Repair: Sufficient for Follow-up?

    SciTech Connect

    Baumueller, Stephan Nguyen, Thi Dan Linh Goetti, Robert Paul; Lachat, Mario; Seifert, Burkhardt; Pfammatter, Thomas Frauenfelder, Thomas

    2011-12-15

    Purpose: To assess the accuracy of maximum diameter measurements of aortic aneurysms after endovascular aneurysm repair (EVAR) on axial computed tomographic (CT) images in comparison to maximum diameter measurements perpendicular to the intravascular centerline for follow-up by using three-dimensional (3D) volume measurements as the reference standard. Materials and Methods: Forty-nine consecutive patients (73 {+-} 7.5 years, range 51-88 years), who underwent EVAR of an infrarenal aortic aneurysm were retrospectively included. Two blinded readers twice independently measured the maximum aneurysm diameter on axial CT images performed at discharge, and at 1 and 2 years after intervention. The maximum diameter perpendicular to the centerline was automatically measured. Volumes of the aortic aneurysms were calculated by dedicated semiautomated 3D segmentation software (3surgery, 3mensio, the Netherlands). Changes in diameter of 0.5 cm and in volume of 10% were considered clinically significant. Intra- and interobserver agreements were calculated by intraclass correlations (ICC) in a random effects analysis of variance. The two unidimensional measurement methods were correlated to the reference standard. Results: Intra- and interobserver agreements for maximum aneurysm diameter measurements were excellent (ICC = 0.98 and ICC = 0.96, respectively). There was an excellent correlation between maximum aneurysm diameters measured on axial CT images and 3D volume measurements (r = 0.93, P < 0.001) as well as between maximum diameter measurements perpendicular to the centerline and 3D volume measurements (r = 0.93, P < 0.001). Conclusion: Measurements of maximum aneurysm diameters on axial CT images are an accurate, reliable, and robust method for follow-up after EVAR and can be used in daily routine.

  18. Prevalence of CT features of axial spondyloarthritis in patients with Crohn's disease.

    PubMed

    De Kock, Isabelle; Hindryckx, Pieter; De Vos, Martine; Delrue, Louke; Verstraete, Koenraad; Jans, Lennart

    2017-05-01

    Background The sacroiliac joint and spine are seen on abdominal computed tomography (CT) and may show structural lesions as part of spondyloarthritis. Purpose To determine the prevalence of CT features of spondyloarthritis in patients with Crohn's disease (CD). Material and Methods A retrospective study of structural lesions of spondyloarthritis on abdominal CT was performed. The sacroiliac joints and spine of 120 patients were studied: study group I consisted of 40 patients with known CD and inflammatory back pain, group II involved 40 patients with CD without inflammatory back pain, and group III consisted of 40 patients without known joint or inflammatory bowel disease. Recorded CT features included sclerosis, erosions or ankylosis of the sacroiliac joint, enthesopathy, spinal syndesmophytes, and costovertebral joint lesions. Results CT showed structural lesions of the sacroiliac joints in 19/40 (48%) patients with CD and inflammatory back pain (sclerosis [n = 14; 35%], erosions [n = 14; 35%], ankylosis [n = 3; 8%]), in 8/40 (8%) patients with CD without inflammatory back pain (sclerosis [n = 3; 8%], erosions [n = 4; 10%], ankylosis [n = 3; 8%]), and in 3/40 (8%) patients without known joint or bowel disease (sclerosis [n = 2; 5%], ankylosis [n = 1; 3%]). Syndesmophytes were exclusively seen in group I (n = 6; 15%). Conclusion CT of the abdomen in patients with CD and inflammatory back pain shows structural lesions of the sacroiliac joint, entheses, or spine in almost half of the patients. Awareness and knowledge of these findings may guide the referring clinician to further clinical evaluation, imaging, and biomarker evaluation of the disease.

  19. Atlas of axial, sagittal and coronal anatomy with CT and MRI

    SciTech Connect

    Christoforidis, A.J.

    1988-01-01

    This book correlates CT scans and nuclear magnetic resonance images with cross sections of all parts of the body-head and neck, thorax, abdomen, male and female pelvis and extremities. Cross sections are fixed, and images are made from the sections to provide exact section-to-scan correlation. Shows all three cross-sectional axes. Includes selected pathologic cases to demonstrate technique.

  20. Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG PET/CT) Findings in an Unusual Case of Multiple Myeloma Presenting with a Large Extra-Axial Intracranial Mass

    PubMed Central

    Ayaz, Sevin; Ayaz, Ümit Yaşar

    2016-01-01

    Summary Background We aimed to present unusual cranial FDG PET/CT findings of a 56-year-old female with multiple myeloma (MM). Case Report Plain CT images revealed a lytic lesion in the right parietal bone, filled with an oval-shaped, large, extra-axial, extradural, intracranial mass which measured 75×75×40 mm and had smooth borders. The right parietal lobe was compressed by the mass. The maximum standardized uptake value (SUVmax) of the mass lesion was 8.94 on FDG PET/CT images. Multiple lytic lesions with an increased uptake were also detected in other calvarial bones, in several vertebras and in the proximal left femur. After seven months, a control FDG PET/CT following radiotherapy and chemotherapy revealed almost complete regression of the right parietal extra-axial mass lesion. The number, size and metabolism of lytic lesions in other bones also decreased. Conclusions FDG PET/CT was useful for an initial evaluation of MM lesions and was effective in monitoring the response of these lesions to therapy. PMID:28058074

  1. Patient radiation dose in prospectively gated axial CT coronary angiography and retrospectively gated helical technique with a 320-detector row CT scanner

    SciTech Connect

    Seguchi, Shigenobu; Aoyama, Takahiko; Koyama, Shuji; Fujii, Keisuke; Yamauchi-Kawaura, Chiyo

    2010-11-15

    Purpose: The aim of this study was to evaluate radiation dose to patients undergoing computed tomography coronary angiography (CTCA) for prospectively gated axial (PGA) technique and retrospectively gated helical (RGH) technique. Methods: Radiation doses were measured for a 320-detector row CT scanner (Toshiba Aquilion ONE) using small sized silicon-photodiode dosimeters, which were implanted at various tissue and organ positions within an anthropomorphic phantom for a standard Japanese adult male. Output signals from photodiode dosimeters were read out on a personal computer, from which organ and effective doses were computed according to guidelines published in the International Commission on Radiological Protection Publication 103. Results: Organs that received high doses were breast, followed by lung, esophagus, and liver. Breast doses obtained with PGA technique and a phase window width of 16% at a simulated heart rate of 60 beats per minute were 13 mGy compared to 53 mGy with RGH technique using electrocardiographically dependent dose modulation at the same phase window width as that in PGA technique. Effective doses obtained in this case were 4.7 and 20 mSv for the PGA and RGH techniques, respectively. Conversion factors of dose length product to the effective dose in PGA and RGH were 0.022 and 0.025 mSv mGy{sup -1} cm{sup -1} with a scan length of 140 mm. Conclusions: CTCA performed with PGA technique provided a substantial effective dose reduction, i.e., 70%-76%, compared to RGH technique using the dose modulation at the same phase windows as those in PGA technique. Though radiation doses in CTCA with RGH technique were the same level as, or some higher than, those in conventional coronary angiography (CCA), the use of PGA technique reduced organ and effective doses to levels less than CCA except for breast dose.

  2. SU-D-9A-04: Brain PET/CT Imaging On a Scanner with a Large Axial Field-Of-View

    SciTech Connect

    Park, M; Gerbaudo, V; Hamberg, L; Seaver, K; Kijewski, M

    2014-06-01

    Purpose: Large axial field-of-view (FOV) PET/CT scanners are valued for high sensitivity. Brain PET image quality may depend on the head position within the FOV. We investigated the precision of activity estimation for brain PET imaging when the brain was positioned at the end (END) and in the middle (CEN) of the FOV. The additional CT dose for the CEN position was recorded. Methods: An image quality (Jaszczak) phantom and a striatal phantom were filled with F-18 and positioned in END and CEN locations. For each phantom and each location, we acquired a ∼1-hr listmode PET, rebinned the data into 10 frames with equal number of coincidence events, and reconstructed each frame using an iterative algorithm. For the striatal phantom, END and CEN were compared by drawing on each image three regions of interest (ROI) in axially separated uniform areas. The standard deviation of the activity estimation within each ROI was averaged over the 10 images. The coefficient of variation (CV) for activity estimation was calculated at each position. Image quality was assessed by inspecting the resolution bar pattern in the Jaszczak phantom at two different head positions. Results: The CV was the lowest for ROIs near the center of the FOV. For slices near the end, not only was the CV highest, but also the resolution pattern was degraded. CTDIvol summarized in the dose report indicated that the CT dose was ∼ 10% higher for CEN as compared to END position. Conclusion: Positioning the brain in the middle of the FOV in a large FOV PET/CT scanner allows more precise measurement of tracer uptake and better image quality at the cost of increased CT dose. For the end location longer scan times may minimize image quality degradation without any additional CT dose.

  3. 18F-NaF PET/CT in Extensive Melorheostosis of the Axial and Appendicular Skeleton With Soft-Tissue Involvement.

    PubMed

    Papadakis, Georgios Z; Jha, Smita; Bhattacharyya, Timothy; Millo, Corina; Tu, Tsang-Wei; Bagci, Ulas; Marias, Kostas; Karantanas, Apostolos H; Patronas, Nicholas J

    2017-03-17

    Melorheostosis is a rare, nonhereditary, benign, sclerotic bone dysplasia with no sex predilection, typically occurring in late childhood or early adulthood, which can lead to substantial functional morbidity, depending on the sites of involvement. We report on a patient with extensive melorheostosis in the axial and appendicular skeleton, as well as in the soft tissues, who was evaluated with whole-body F-NaF PET/CT scan. All melorheostotic lesions of the skeleton and of the ossified soft-tissue masses demonstrated intensely increased F-NaF activity, suggesting the application of this modality in assessing and monitoring the disease activity.

  4. SU-E-I-15: Quantitative Evaluation of Dose Distributions From Axial, Helical and Cone-Beam CT Imaging by Measurement Using a Two-Dimensional Diode-Array Detector

    SciTech Connect

    Chacko, M; Aldoohan, S; Sonnad, J; Ahmad, S; Ali, I

    2015-06-15

    Purpose: To evaluate quantitatively dose distributions from helical, axial and cone-beam CT clinical imaging techniques by measurement using a two-dimensional (2D) diode-array detector. Methods: 2D-dose distributions from selected clinical protocols used for axial, helical and cone-beam CT imaging were measured using a diode-array detector (MapCheck2). The MapCheck2 is composed from solid state diode detectors that are arranged in horizontal and vertical lines with a spacing of 10 mm. A GE-Light-Speed CT-simulator was used to acquire axial and helical CT images and a kV on-board-imager integrated with a Varian TrueBeam-STx machine was used to acquire cone-beam CT (CBCT) images. Results: The dose distributions from axial, helical and cone-beam CT were non-uniform over the region-of-interest with strong spatial and angular dependence. In axial CT, a large dose gradient was measured that decreased from lateral sides to the middle of the phantom due to large superficial dose at the side of the phantom in comparison with larger beam attenuation at the center. The dose decreased at the superior and inferior regions in comparison to the center of the phantom in axial CT. An asymmetry was found between the right-left or superior-inferior sides of the phantom which possibly to angular dependence in the dose distributions. The dose level and distribution varied from one imaging technique into another. For the pelvis technique, axial CT deposited a mean dose of 3.67 cGy, helical CT deposited a mean dose of 1.59 cGy, and CBCT deposited a mean dose of 1.62 cGy. Conclusions: MapCheck2 provides a robust tool to measure directly 2D-dose distributions for CT imaging with high spatial resolution detectors in comparison with ionization chamber that provides a single point measurement or an average dose to the phantom. The dose distributions measured with MapCheck2 consider medium heterogeneity and can represent specific patient dose.

  5. The impact of x-ray tube stabilization on localized radiation dose in axial CT scans: initial results in CTDI phantoms

    NASA Astrophysics Data System (ADS)

    Mathieu, Kelsey B.; McNitt-Gray, Michael F.; Cody, Dianna D.

    2016-10-01

    Rise, fall, and stabilization of the x-ray tube output occur immediately before and after data acquisition on some computed tomography (CT) scanners and are believed to contribute additional dose to anatomy facing the x-ray tube when it powers on or off. In this study, we characterized the dose penalty caused by additional radiation exposure during the rise, stabilization, and/or fall time (referred to as overscanning). A 32 cm CT dose-index (CTDI) phantom was scanned on three CT scanners: GE Healthcare LightSpeed VCT, GE Healthcare Discovery CT750 HD, and Siemens Somatom Definition Flash. Radiation exposure was detected for various x-ray tube start acquisition angles using a 10 cm pencil ionization chamber placed in the peripheral chamber hole at the phantom’s 12 o’clock position. Scan rotation time, ionization chamber location, phantom diameter, and phantom centering were varied to quantify their effects on the dose penalty caused by overscanning. For 1 s single, axial rotations, CTDI at the 12 o’clock chamber position (CTDI100, 12:00) was 6.1%, 4.0%, and 4.4% higher when the start angle of the x-ray tube was aligned at the top of the gantry (12 o’clock) versus when the start angle was aligned at 9 o’clock for the Siemens Flash, GE CT750 HD, and GE VCT scanner, respectively. For the scanners’ fastest rotation times (0.285 s for the Siemens and 0.4 s for both GE scanners), the dose penalties increased to 22.3%, 10.7%, and 10.5%, respectively, suggesting a trade-off between rotation speed and the dose penalty from overscanning. In general, overscanning was shown to have a greater radiation dose impact for larger diameter phantoms, shorter rotation times, and to peripheral phantom locations. Future research is necessary to determine an appropriate method for incorporating the localized dose penalty from overscanning into standard dose metrics, as well as to assess the impact on organ dose.

  6. Quantitative estimation of a ratio of intracranial cerebrospinal fluid volume to brain volume based on segmentation of CT images in patients with extra-axial hematoma.

    PubMed

    Nguyen, Ha Son; Patel, Mohit; Li, Luyuan; Kurpad, Shekar; Mueller, Wade

    2017-02-01

    Background Diminishing volume of intracranial cerebrospinal fluid (CSF) in patients with space-occupying masses have been attributed to unfavorable outcome associated with reduction of cerebral perfusion pressure and subsequent brain ischemia. Objective The objective of this article is to employ a ratio of CSF volume to brain volume for longitudinal assessment of space-volume relationships in patients with extra-axial hematoma and to determine variability of the ratio among patients with different types and stages of hematoma. Patients and methods In our retrospective study, we reviewed 113 patients with surgical extra-axial hematomas. We included 28 patients (age 61.7 +/- 17.7 years; 19 males, nine females) with an acute epidural hematoma (EDH) ( n = 5) and subacute/chronic subdural hematoma (SDH) ( n = 23). We excluded 85 patients, in order, due to acute SDH ( n = 76), concurrent intraparenchymal pathology ( n = 6), and bilateral pathology ( n = 3). Noncontrast CT images of the head were obtained using a CT scanner (2004 GE LightSpeed VCT CT system, tube voltage 140 kVp, tube current 310 mA, 5 mm section thickness) preoperatively, postoperatively (3.8 ± 5.8 hours from surgery), and at follow-up clinic visit (48.2 ± 27.7 days after surgery). Each CT scan was loaded into an OsiriX (Pixmeo, Switzerland) workstation to segment pixels based on radiodensity properties measured in Hounsfield units (HU). Based on HU values from -30 to 100, brain, CSF spaces, vascular structures, hematoma, and/or postsurgical fluid were segregated from bony structures, and subsequently hematoma and/or postsurgical fluid were manually selected and removed from the images. The remaining images represented overall brain volume-containing only CSF spaces, vascular structures, and brain parenchyma. Thereafter, the ratio between the total number of voxels representing CSF volume (based on values between 0 and 15 HU) to the total number of voxels

  7. Accuracy of finite element analyses of CT scans in predictions of vertebral failure patterns under axial compression and anterior flexion.

    PubMed

    Jackman, Timothy M; DelMonaco, Alex M; Morgan, Elise F

    2016-01-25

    Finite element (FE) models built from quantitative computed tomography (QCT) scans can provide patient-specific estimates of bone strength and fracture risk in the spine. While prior studies demonstrate accurate QCT-based FE predictions of vertebral stiffness and strength, the accuracy of the predicted failure patterns, i.e., the locations where failure occurs within the vertebra and the way in which the vertebra deforms as failure progresses, is less clear. This study used digital volume correlation (DVC) analyses of time-lapse micro-computed tomography (μCT) images acquired during mechanical testing (compression and anterior flexion) of thoracic spine segments (T7-T9, n=28) to measure displacements occurring throughout the T8 vertebral body at the ultimate point. These displacements were compared to those simulated by QCT-based FE analyses of T8. We hypothesized that the FE predictions would be more accurate when the boundary conditions are based on measurements of pressure distributions within intervertebral discs of similar level of disc degeneration vs. boundary conditions representing rigid platens. The FE simulations captured some of the general, qualitative features of the failure patterns; however, displacement errors ranged 12-279%. Contrary to our hypothesis, no differences in displacement errors were found when using boundary conditions representing measurements of disc pressure vs. rigid platens. The smallest displacement errors were obtained using boundary conditions that were measured directly by DVC at the T8 endplates. These findings indicate that further work is needed to develop methods of identifying physiological loading conditions for the vertebral body, for the purpose of achieving robust, patient-specific FE analyses of failure mechanisms.

  8. Accuracy of finite element analyses of CT scans in predictions of vertebral failure patterns under axial compression and anterior flexion

    PubMed Central

    Jackman, Timothy M.; DelMonaco, Alex M.; Morgan, Elise F.

    2016-01-01

    Finite element (FE) models built from quantitative computed tomography (QCT) scans can provide patient-specific estimates of bone strength and fracture risk in the spine. While prior studies demonstrate accurate QCT-based FE predictions of vertebral stiffness and strength, the accuracy of the predicted failure patterns, i.e., the locations where failure occurs within the vertebra and the way in which the vertebra deforms as failure progresses, is less clear. This study used digital volume correlation (DVC) analyses of time-lapse micro-computed tomography (µCT) images acquired during mechanical testing (compression and anterior flexion) of thoracic spine segments (T7–T9, n = 28) to measure displacements occurring throughout the T8 vertebral body at the ultimate point. These displacements were compared to those simulated by QCT-based FE analyses of T8. We hypothesized that the FE predictions would be more accurate when the boundary conditions are based on measurements of pressure distributions within intervertebral discs of similar level of disc degeneration vs. boundary conditions representing rigid platens. The FE simulations captured some of the general, qualitative features of the failure patterns; however, displacement errors ranged 12–279%. Contrary to our hypothesis, no differences in displacement errors were found when using boundary conditions representing measurements of disc pressure vs. rigid platens. The smallest displacement errors were obtained using boundary conditions that were measured directly by DVC at the T8 endplates. These findings indicate that further work is needed to develop methods of identifying physiological loading conditions for the vertebral body, for the purpose of achieving robust, patient-specific FE analyses of failure mechanisms. PMID:26792288

  9. Computerised Axial Tomography (CAT)

    DTIC Science & Technology

    1990-06-01

    OF COMPUTERISED AXIAL TOMOGRAPHY Paragraph 1.1 ORIGIN, DEVELOPMENT AND MARKET OF CAT Paragraph 1.2 EQUIPMENT Chapter 2 OPERATIONAL PRINCIPLE OF A CT...DEVELOPMENT OF THE COMPUTERISED AXIAL TOMOGRAPHY 1.1 Origin, development and marketing of the CAT The origin of the CAT goes back to 1961 when...count on wide commercial possibilities, in the international market . In particular, EMI entered, very forcefully, the American market , always

  10. Rare and challenging extra-axial brain lesions: CT and MRI findings with clinico-radiological differential diagnosis and pathological correlation

    PubMed Central

    Demir, Mustafa Kemal; Yapıcıer, Özlem; Onat, Elif; Toktaş, Zafer Orkun; Akakın, Akın; Urgun, Kamran; Kılıç, Türker

    2014-01-01

    There are many kinds of extra-axial brain tumors and tumor-like lesions, and definitive diagnosis is complicated in some cases. In this pictorial essay, we present rare and challenging extra-axial brain lesions including neuroenteric cyst, primary leptomeningeal melanomatosis, isolated dural neurosarcoidosis, intradiploic epidermoid cyst, ruptured dermoid cyst, intraventricular cavernoma, and cavernous hemangioma of the skull with imaging findings and clinico-radiological differential diagnosis, including the pathologic correlation. Familiarity with these entities may improve diagnostic accuracy and patient management. PMID:25010368

  11. Axial spondyloarthritis.

    PubMed

    Sieper, Joachim; Braun, Jürgen; Dougados, Maxime; Baeten, Dominique

    2015-07-09

    The term axial spondyloarthritis covers both non-radiographic disease and radiographic disease (also known as ankylosing spondylitis). Some studies have been performed to investigate the prevalence of axial spondyloarthritis, although most are limited to patients with radiographic disease. A strong genetic association has been shown between axial spondyloarthritis and human leukocyte antigen-B27 (HLA-B27), but the pathogenetic role of HLA-B27 has not yet been clarified. Tumour necrosis factor (TNF), IL-17, IL-23 and downstream pathways also seem to be important - based on the good results of therapies directed against these molecules - but their exact role in the inflammatory process is also not yet clear. Elucidating the interaction between osteoproliferation and inflammation will be crucial for the prevention of long-term structural damage of the bone. The development of new criteria for classification, diagnosis and screening of patients with axial spondyloarthritis will enable earlier intervention for this chronic inflammatory disease. MRI has become an important tool for the early detection of axial spondyloarthritis. NSAIDs and TNF blockers are effective therapies, including in the early non-radiographic stage. Therapeutic blockade of IL-17 or IL-23 seems to be a promising new treatment option. Tools for measuring quality of life in axial spondyloarthritis have become relevant to assess the impact that the disease has on patients. These diagnostic and therapeutic advances will continue to change the management of axial spondyloarthritis, and new insights into the disease pathogenesis will hopefully accelerate this process. For an illustrated summary of this Primer, visit: http://go.nature.com/51b1af.

  12. Leg CT scan

    MedlinePlus

    CAT scan - leg; Computed axial tomography scan - leg; Computed tomography scan - leg; CT scan - leg ... scanners can perform the exam without stopping.) A computer creates separate images of the body area, called ...

  13. Arm CT scan

    MedlinePlus

    CAT scan - arm; Computed axial tomography scan - arm; Computed tomography scan - arm; CT scan - arm ... scanners can perform the exam without stopping.) A computer creates separate images of the arm area, called ...

  14. Lumbar spine CT scan

    MedlinePlus

    CAT scan - lumbar spine; Computed axial tomography scan - lumbar spine; Computed tomography scan - lumbar spine; CT - lower back ... stopping.) A computer creates separate images of the spine area, called slices. These images can be stored, ...

  15. Can Parameters Other than Minimal Axial Diameter in MRI and PET/CT Further Improve Diagnostic Accuracy for Equivocal Retropharyngeal Lymph Nodes in Nasopharyngeal Carcinoma?

    PubMed Central

    Wu, Chin-Shun; Zhang, Guo-Yi; Chang, Chih-Han; Cheng, Kuo-Sheng; Yao, Wei-Jen; Chang, Yu-Kang; Chien, Tsair-Wei; Lin, Li-Ching; Lin, Keng-Ren

    2016-01-01

    Purpose Minimal axial diameter (MIAD) in magnetic resonance imaging (MRI) was recognized as the most useful parameter in diagnosing lateral retropharyngeal lymph (LRPL) nodes in nasopharyngeal carcinoma (NPC). This study aims to explore the additional nodal parameters in MRI and positron emission tomography–computed tomography for increasing the prediction accuracy. Materials and Methods A total of 663 LRPL nodes were retrospectively collected from 335 patients with NPC. The LRPL nodes ascertained on follow-up MRI were considered positive for metastases. First, the optimal cutoff value of each parameter was derived for each parameter. In addition, neural network (NN) nodal evaluation was tested for all combinations of three parameters, namely MIAD, maximal axial diameter (MAAD), and maximal coronal diameter (MACD). The optimal approach was determined through brute force attack, and the results of two methods were compared using a bootstrap sampling method. Second, the mean standard uptake value (NSUVmean) was added as the fourth parameter and tested in the same manner for 410 nodes in 219 patients. Results In first and second analysis, the accuracy rate (percentage) for the MIAD was 89.0% (590/663) and 89.0% (365/410), with the optimal cutoff values being 6.1 mm and 6.0 mm, respectively. With the combination of all three and four parameters, the accuracy rate of the NN was 89% (288/332) and 88.8% (182/205), respectively. In prediction, the optimal combinations of the three and four parameters resulted in correct identification of three (accuracy: 593/663, 89.4%) and six additional nodes (371/410, 90.5%), representing 4% (3/73) and 13.3% (6/45) decreases in incorrect prediction, respectively. Conclusion NPC LRPL nodes with an MIAD ≥ 6.1 mm are positive. Among nodes with an MIAD < 6.1 mm, if the NSUVmean ≥ 2.6 or MACD ≥ 25 mm and MAAD ≥ 8 mm, the nodes are positive; otherwise, they are negative. PMID:27736927

  16. Axial Pump

    NASA Technical Reports Server (NTRS)

    Bozeman, Richard J., Jr. (Inventor); Akkerman, James W. (Inventor); Aber, Gregory S. (Inventor); VanDamm, George Arthur (Inventor); Bacak, James W. (Inventor); Svejkovsky, Paul A. (Inventor); Benkowski, Robert J. (Inventor)

    1997-01-01

    A rotary blood pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial and radial clearances of blades associated with the flow straightener, inducer portion, impeller portion and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with cross-linked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

  17. Application of the Low-dose One-stop-shop Cardiac CT Protocol with Third-generation Dual-source CT.

    PubMed

    Lin, Lu; Wang, Yining; Yi, Yan; Cao, Jian; Kong, Lingyan; Qian, Hao; Zhang, Hongzhi; Wu, Wei; Wang, Yun; Jin, Zhengyu

    2017-02-20

    Objective To evaluate the feasibility of a low-dose one-stop-shop cardiac CT imaging protocol with third-generation dual-source CT (DSCT). Methods Totally 23 coronary artery disease (CAD) patients were prospectively enrolled between March to September in 2016. All patients underwent an ATP stress dynamic myocardial perfusion imaging (MPI) (data acquired prospectively ECG-triggered during end systole by table shuttle mode in 32 seconds) at 70 kV combined with prospectively ECG-triggered high-pitch coronary artery angiography (CCTA) on a third-generation DSCT system. Myocardial blood flow (MBF) was quantified and compared between perfusion normal and abnormal myocardial segments based on AHA-17-segment model. CCTA images were evaluated qualitatively based on SCCT-18-segment model and the effective dose(ED) was calculated. In patients with subsequent catheter coronary angiography (CCA) as reference,the diagnosis performance of MPI (for per-vessel ≥50% and ≥70% stenosis) and CCTA (for≥50% stenosis) were assessed. Results Of 23 patients who had completed the examination of ATP stress MPI plus CCTA,12 patients received follow-up CCA. At ATP stress MPI,77 segments (19.7%) in 13 patients (56.5%) had perfusion abnormalities. The MBF values of hypo-perfused myocardial segments decreased significantly compared with normal segments [(93±22)ml/(100 ml·min) vs. (147±27)ml/(100 ml·min);t=15.978,P=0.000]. At CCTA,93.9% (308/328) of the coronary segments had diagnostic image quality. With CCA as the reference standard,the per-vessel and per-segment sensitivity,specificity,and accuracy of CCTA for stenosis≥50% were 94.1%,93.5%,and 93.7% and 90.9%,97.8%,and 96.8%,and the per-vessel sensitivity,specificity and accuracy of ATP stress MPI for stenosis≥50% and ≥70% were 68.7%,100%,and 89.5% and 91.7%,100%,and 97.9%. The total ED of MPI and CCTA was (3.9±1.3) mSv [MPI:(3.5±1.2) mSv,CCTA:(0.3±0.1) mSv]. Conclusion The third-generation DSCT stress dynamic MPI at 70 k

  18. Axial superchargers

    NASA Technical Reports Server (NTRS)

    Betz, A

    1944-01-01

    Improvements, however, have been attained which permit a shortening of the structure without any impairment of the efficiency. The axial supercharger has a better efficiency and a simpler design than the radial supercharger. The relatively narrow range in which it operates satisfactorily should not be a very disturbing factor for practical flight problems. The length of this type of supercharger may be reduced considerably if some impairment in the efficiency is permitted.

  19. Compressive axial mechanical properties of rat bone as functions of bone volume fraction, apparent density and micro-ct based mineral density.

    PubMed

    Cory, Esther; Nazarian, Ara; Entezari, Vahid; Vartanians, Vartan; Müller, Ralph; Snyder, Brian D

    2010-03-22

    Mechanical testing has been regarded as the gold standard to investigate the effects of pathologies on the structure-function properties of the skeleton. With recent advances in computing power of personal computers, virtual alternatives to mechanical testing are gaining acceptance and use. We have previously introduced such a technique called structural rigidity analysis to assess mechanical strength of skeletal tissue with defects. The application of this technique is predicated upon the use of relationships defining the strength of bone as a function of its density for a given loading mode. We are to apply this technique in rat models to assess their compressive skeletal response subjected to a host of biological and pharmaceutical stimulations. Therefore, the aim of this study is to derive a relationship expressing axial compressive mechanical properties of rat cortical and cancellous bone as a function of equivalent bone mineral density, bone volume fraction or apparent density over a range of normal and pathologic bones. We used bones from normal, ovariectomized and partially nephrectomized animals. All specimens underwent micro-computed tomographic imaging to assess bone morphometric and densitometric indices and uniaxial compression to failure. We obtained univariate relationships describing 71-78% of the mechanical properties of rat cortical and cancellous bone based on equivalent mineral density, bone volume fraction or apparent density over a wide range of density and common skeletal pathologies. The relationships reported in this study can be used in the structural rigidity analysis introduced by the authors to provide a non-invasive method to assess the compressive strength of bones affected by pathology and/or treatment options.

  20. Computed tomography of axial skeletal osteoid osteomas

    SciTech Connect

    Gamba, J.L.; Martinez, S.; Apple, J.; Harrelson, J.M.; Nunley, J.A.

    1984-04-01

    Five cases of axial skeletal osteoid osteomas were viewed with particular attention to the role of computed tomography (CT) as a key diagnostic tool in the evaluation of osteoid osteoma. The complex anatomy of the axial skeleton can make the diagnosis of osteoid osteoma extremely difficult on routine films or tomograms, and the lesion often is well delineated only on CT scans. As complete surgical excision of this benign bony tumor is curative, precise anatomic localization is essential to the surgeon. Conventional radiographs were normal in all patients. Bone scans were positive when obtained and were useful in localizing the lesion and directing CT to the appropriate level. In all five cases CT was of proven value in accurately demonstrating the location, nidus, and other characteristic diagnostic radiographic features of osteoid osteoma.

  1. CT of pituitary abscess

    SciTech Connect

    Fong, T.C.; Johns, R.D.; Long, M.; Myles, S.T.

    1985-06-01

    Pituitary abscess is a rare condition, with only 50 cases reported in the literature. Of those, 29 cases were well documented for analysis. Preoperative diagnosis of pituitary abscess is difficult. The computed tomographic (CT) appearance of pituitary abscess was first described in 1983; the abscess was depicted by axial images with coronal reconstruction. The authors recently encountered a case of pituitary abscess documented by direct coronal CT of the sella turcica.

  2. CT evaluation prior to transapical aortic valve replacement: semi-automatic versus manual image segmentation.

    PubMed

    Foldyna, Borek; Jungert, Camelia; Luecke, Christian; von Aspern, Konstantin; Boehmer-Lasthaus, Sonja; Rueth, Eva Maria; Grothoff, Matthias; Nitzsche, Stefan; Gutberlet, Matthias; Mohr, Friedrich Wilhelm; Lehmkuhl, Lukas

    2015-08-01

    To compare the performance of semi-automatic versus manual segmentation for ECG-triggered cardiovascular computed tomography (CT) examinations prior to transcatheter aortic valve replacement (TAVR), with focus on the speed and precision of experienced versus inexperienced observers. The preoperative ECG-triggered CT data of 30 consecutive patients who were scheduled for TAVR were included. All datasets were separately evaluated by two radiologists with 1 and 5 years of experience (novice and expert, respectively) in cardiovascular CT using an evaluation software program with or without a semi-automatic TAVR workflow. The time expended for data loading and all segmentation steps required for the implantation planning were assessed. Inter-software as well as inter-observer reliability analysis was performed. The CT datasets were successfully evaluated, with mean duration between 520.4 ± 117.6 s and 693.2 ± 159.5 s. The three most time-consuming steps were the 3D volume rendering, the measurement of aorta diameter and the sizing of the aortic annulus. Using semi-automatic segmentation, a novice could evaluate CT data approximately 12.3% faster than with manual segmentation, and an expert could evaluate CT data approximately 10.3% faster [mean differences of 85.4 ± 83.8 s (p < 0.001) and 59.8 ± 101 s (p < 0.001), respectively]. The inter-software reliability for a novice was slightly lower than for an expert; however, the reliability for a novice and expert was excellent (ICC 0.92, 95% CI 0.75-0.97/ICC 0.96, 95% CI 0.91-0.98). Automatic aortic annulus detection failed in two patients (6.7%). The study revealed excellent inter-software and inter-observer reliability, with a mean ICC of 0.95. TAVR evaluation can be accomplished significantly faster with semi-automatic rather than with manual segmentation, with comparable exactness, showing a benefit for experienced and inexperienced observers.

  3. Dynamic CT myocardial perfusion imaging: detection of ischemia in a porcine model with FFR verification

    NASA Astrophysics Data System (ADS)

    Fahmi, Rachid; Eck, Brendan L.; Vembar, Mani; Bezerra, Hiram G.; Wilson, David L.

    2014-03-01

    Dynamic cardiac CT perfusion (CTP) is a high resolution, non-invasive technique for assessing myocardial blood ow (MBF), which in concert with coronary CT angiography enable CT to provide a unique, comprehensive, fast analysis of both coronary anatomy and functional ow. We assessed perfusion in a porcine model with and without coronary occlusion. To induce occlusion, each animal underwent left anterior descending (LAD) stent implantation and angioplasty balloon insertion. Normal ow condition was obtained with balloon completely de ated. Partial occlusion was induced by balloon in ation against the stent with FFR used to assess the extent of occlusion. Prospective ECG-triggered partial scan images were acquired at end systole (45% R-R) using a multi-detector CT (MDCT) scanner. Images were reconstructed using FBP and a hybrid iterative reconstruction (iDose4, Philips Healthcare). Processing included: beam hardening (BH) correction, registration of image volumes using 3D cubic B-spline normalized mutual-information, and spatio-temporal bilateral ltering to reduce partial scan artifacts and noise variation. Absolute blood ow was calculated with a deconvolutionbased approach using singular value decomposition (SVD). Arterial input function was estimated from the left ventricle (LV) cavity. Regions of interest (ROIs) were identi ed in healthy and ischemic myocardium and compared in normal and occluded conditions. Under-perfusion was detected in the correct LAD territory and ow reduction agreed well with FFR measurements. Flow was reduced, on average, in LAD territories by 54%.

  4. Light axial vector mesons

    NASA Astrophysics Data System (ADS)

    Chen, Kan; Pang, Cheng-Qun; Liu, Xiang; Matsuki, Takayuki

    2015-04-01

    Inspired by the abundant experimental observation of axial-vector states, we study whether the observed axial-vector states can be categorized into the conventional axial-vector meson family. In this paper we carry out an analysis based on the mass spectra and two-body Okubo-Zweig-Iizuka-allowed decays. Besides testing the possible axial-vector meson assignments, we also predict abundant information for their decays and the properties of some missing axial-vector mesons, which are valuable for further experimental exploration of the observed and predicted axial-vector mesons.

  5. CT Enterography

    MedlinePlus

    ... obstructions and Crohn’s disease. CT scanning is fast, painless, noninvasive and accurate. CT enterography is better able ... the benefits vs. risks? Benefits CT scanning is painless, noninvasive and accurate. A major advantage of CT ...

  6. BWR AXIAL PROFILE

    SciTech Connect

    J. Huffer

    2004-09-28

    The purpose of this calculation is to develop axial profiles for estimating the axial variation in burnup of a boiling water reactor (BWR) assembly spent nuclear fuel (SNF) given the average burnup of an assembly. A discharged fuel assembly typically exhibits higher burnup in the center and lower burnup at the ends of the assembly. Criticality safety analyses taking credit for SNF burnup must account for axially varying burnup relative to calculations based on uniformly distributed assembly average burnup due to the under-burned tips. Thus, accounting for axially varying burnup in criticality analyses is also referred to as accounting for the ''end effect'' reactivity. The magnitude of the reactivity change due to ''end effect'' is dependent on the initial assembly enrichment, the assembly average burnup, and the particular axial profile characterizing the burnup distribution. The set of bounding axial profiles should incorporate multiple BWR core designs and provide statistical confidence (95 percent confidence that 95 percent of the population is bound by the profile) that end nodes are conservatively represented. The profiles should also conserve the overall burnup of the fuel assembly. More background on BWR axial profiles is provided in Attachment I.

  7. Measuring axial pump thrust

    DOEpatents

    Suchoza, Bernard P.; Becse, Imre

    1988-01-01

    An apparatus for measuring the hydraulic axial thrust of a pump under operation conditions is disclosed. The axial thrust is determined by forcing the rotating impeller off of an associated thrust bearing by use of an elongate rod extending coaxially with the pump shaft. The elongate rod contacts an impeller retainer bolt where a bearing is provided. Suitable measuring devices measure when the rod moves to force the impeller off of the associated thrust bearing and the axial force exerted on the rod at that time. The elongate rod is preferably provided in a housing with a heat dissipation mechanism whereby the hot fluid does not affect the measuring devices.

  8. Measuring axial pump thrust

    DOEpatents

    Suchoza, B.P.; Becse, I.

    1988-11-08

    An apparatus for measuring the hydraulic axial thrust of a pump under operation conditions is disclosed. The axial thrust is determined by forcing the rotating impeller off of an associated thrust bearing by use of an elongate rod extending coaxially with the pump shaft. The elongate rod contacts an impeller retainer bolt where a bearing is provided. Suitable measuring devices measure when the rod moves to force the impeller off of the associated thrust bearing and the axial force exerted on the rod at that time. The elongate rod is preferably provided in a housing with a heat dissipation mechanism whereby the hot fluid does not affect the measuring devices. 1 fig.

  9. Axial static mixer

    DOEpatents

    Sandrock, H.E.

    1982-05-06

    Static axial mixing apparatus includes a plurality of channels, forming flow paths of different dimensions. The axial mixer includes a flow adjusting device for adjustable selective control of flow resistance of various flow paths in order to provide substantially identical flows through the various channels, thereby reducing nonuniform coating of interior surfaces of the channels. The flow adjusting device may include diaphragm valves, and may further include a pressure regulating system therefor.

  10. Axial Halbach Magnetic Bearings

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.; Gallo, Christopher A.; Thompson, William K.

    2008-01-01

    Axial Halbach magnetic bearings have been investigated as part of an effort to develop increasingly reliable noncontact bearings for future high-speed rotary machines that may be used in such applications as aircraft, industrial, and land-vehicle power systems and in some medical and scientific instrumentation systems. Axial Halbach magnetic bearings are passive in the sense that unlike most other magnetic bearings that have been developed in recent years, they effect stable magnetic levitation without need for complex active control.

  11. CT Scans

    MedlinePlus

    ... cross-sectional pictures of your body. Doctors use CT scans to look for Broken bones Cancers Blood clots Signs of heart disease Internal bleeding During a CT scan, you lie still on a table. The table ...

  12. Altered Axial Skeletal Development

    EPA Science Inventory

    The axial skeleton is routinely examined in standard developmental toxicity bioassays and has proven to be sensitive to a wide variety of chemical agents. Dysmorphogenesis in the skull, vertebral column and ribs has been described in both human populations and in laboratory anima...

  13. Correlation of CT cerebral vascular territories with function. 3. Middle cerebral artery

    SciTech Connect

    Berman, S.A.; Hayman, L.A.; Hinck, V.C.

    1984-05-01

    Schematic displays are presented of the cerebral territories supplied by branches of the middle cerebral artery as they would appear on axial and coronal computed tomographic (CT) scan sections. Companion diagrams of regional cortical function and a discussion of the fiber tracts are provided to simplify correlation of clinical deficits with coronal and axial CT abnormalities.

  14. CT Image Presentations For Oral Surgery

    NASA Astrophysics Data System (ADS)

    Rhodes, Michael L.; Rothman, Stephen L. G.; Schwarz, Melvyn S.; Tivattanasuk, Eva S.

    1988-06-01

    Reformatted CT images of the mandible and maxilla are described as a planning aid to the surgical implantation of dental fixtures. Precisely scaled and cross referenced axial, oblique, CT generated panorex, and 3-D images are generated to help indicate where and how critical anatomic structures are positioned. This information guides the oral surgeon to those sites where dental implants have optimal osteotic support and least risk to sensitive neural tissue. Oblique images are generated at 1-2 mm increments along the arch of the mandible (or maxilla). Each oblique is oriented perpendicular to the local arch curvature. The adjoining five CT generated panorex views match the patient's mandibular (or maxilla) arch, with each of the views separated by twice the distance between axial CT slices. All views are mutually cross-referenced to show fine detail of the underlying mandibular (or maxilla) structure. Several exams are illustrated and benefit to subsequent surgery is assessed.

  15. Head CT scan

    MedlinePlus

    Brain CT; Cranial CT; CT scan - skull; CT scan - head; CT scan - orbits; CT scan - sinuses; Computed tomography - cranial; CAT scan - brain ... conditions: Birth (congenital) defect of the head or brain Brain infection Brain tumor Buildup of fluid inside ...

  16. Dual source CT (DSCT) imaging of obese patients: evaluation of CT number accuracy, uniformity, and noise

    NASA Astrophysics Data System (ADS)

    Walz-Flannigan, A.; Schmidt, B.,; Apel, A.; Eusemann, C.; Yu, L.; McCollough, C. H.

    2009-02-01

    Obese patients present challenges in obtaining sufficient x-ray exposure over reasonable time periods for acceptable CT image quality. To overcome this limitation, the exposure can be divided between two x-ray sources using a dualsource (DS) CT system. However, cross-scatter issues in DS CT may also compromise image quality. We evaluated a DS CT system optimized for imaging obese patients, comparing the CT number accuracy and uniformity to the same images obtained with a single-source (SS) acquisition. The imaging modes were compared using both solid cylindrical PMMA phantoms and a semi-anthropomorphic thorax phantom fitted with extension rings to simulate different size patients. Clinical protocols were used and CTDIvol and kVp were held constant between SS and DS modes. Results demonstrated good agreement in CT number between SS and DS modes in CT number, with the DS mode showing better axial uniformity for the largest phantoms.

  17. Axial Plane Optical Microscopy

    PubMed Central

    Li, Tongcang; Ota, Sadao; Kim, Jeongmin; Wong, Zi Jing; Wang, Yuan; Yin, Xiaobo; Zhang, Xiang

    2014-01-01

    We present axial plane optical microscopy (APOM) that can, in contrast to conventional microscopy, directly image a sample's cross-section parallel to the optical axis of an objective lens without scanning. APOM combined with conventional microscopy simultaneously provides two orthogonal images of a 3D sample. More importantly, APOM uses only a single lens near the sample to achieve selective-plane illumination microscopy, as we demonstrated by three-dimensional (3D) imaging of fluorescent pollens and brain slices. This technique allows fast, high-contrast, and convenient 3D imaging of structures that are hundreds of microns beneath the surfaces of large biological tissues. PMID:25434770

  18. GEOS axial booms

    NASA Technical Reports Server (NTRS)

    Schmidt, G. K.

    1979-01-01

    A booms and mechanisms subsystem was designed, developed, and qualified for the geostationary scientific satellite GEOS. Part of this subsystem consist of four axial booms consisting of one pair of 1 m booms and one pair of 2.5 m booms. Each of these booms is carrying one bird cage electric field sensor. Alignment accuracy requirements led to a telescopic type solution. Deployment is performed by pressurized nitrogen. At deployment in orbit two of these booms showed some anomalies and one of these two deployed only about 80%. Following this malfunction a detailed failure investigation was performed resulting in a design modification of some critical components as release mechanism, guide sleeves of the telescopic elements, and pressure system.

  19. Deep convolutional neural networks for automatic coronary calcium scoring in a screening study with low-dose chest CT

    NASA Astrophysics Data System (ADS)

    Lessmann, Nikolas; Išgum, Ivana; Setio, Arnaud A. A.; de Vos, Bob D.; Ciompi, Francesco; de Jong, Pim A.; Oudkerk, Matthjis; Mali, Willem P. Th. M.; Viergever, Max A.; van Ginneken, Bram

    2016-03-01

    The amount of calcifications in the coronary arteries is a powerful and independent predictor of cardiovascular events and is used to identify subjects at high risk who might benefit from preventive treatment. Routine quantification of coronary calcium scores can complement screening programs using low-dose chest CT, such as lung cancer screening. We present a system for automatic coronary calcium scoring based on deep convolutional neural networks (CNNs). The system uses three independently trained CNNs to estimate a bounding box around the heart. In this region of interest, connected components above 130 HU are considered candidates for coronary artery calcifications. To separate them from other high intensity lesions, classification of all extracted voxels is performed by feeding two-dimensional 50 mm × 50 mm patches from three orthogonal planes into three concurrent CNNs. The networks consist of three convolutional layers and one fully-connected layer with 256 neurons. In the experiments, 1028 non-contrast-enhanced and non-ECG-triggered low-dose chest CT scans were used. The network was trained on 797 scans. In the remaining 231 test scans, the method detected on average 194.3 mm3 of 199.8 mm3 coronary calcifications per scan (sensitivity 97.2 %) with an average false-positive volume of 10.3 mm3 . Subjects were assigned to one of five standard cardiovascular risk categories based on the Agatston score. Accuracy of risk category assignment was 84.4 % with a linearly weighted κ of 0.89. The proposed system can perform automatic coronary artery calcium scoring to identify subjects undergoing low-dose chest CT screening who are at risk of cardiovascular events with high accuracy.

  20. Axial disease in psoriatic arthritis.

    PubMed

    Gladman, Dafna D

    2007-12-01

    The definition of axial disease in psoriatic arthritis has varied from isolated unilateral grade 2 sacroiliitis to criteria similar to those used for ankylosing spondylitis. Depending on the definition used, the prevalence of axial disease varies from 25% to 70% of patients with psoriatic arthritis. This article reviews the prevalence, clinical and radiologic features, pathogenesis, prognosis, and treatment of psoriatic spondylitis.

  1. Identification of an intra-cranial intra-axial porcupine quill foreign body with computed tomography in a canine patient.

    PubMed

    Sauvé, Christopher P; Sereda, Nikki C; Sereda, Colin W

    2012-02-01

    An intra-cranial intra-axial foreign body was diagnosed in a golden retriever dog through the use of computed tomography (CT). Confirmed by necropsy, a porcupine quill had migrated to the patient's left cerebral hemisphere, likely through the oval foramen. This case study demonstrates the efficacy of CT in visualizing a quill in the canine brain.

  2. Axial gap rotating electrical machine

    DOEpatents

    None

    2016-02-23

    Direct drive rotating electrical machines with axial air gaps are disclosed. In these machines, a rotor ring and stator ring define an axial air gap between them. Sets of gap-maintaining rolling supports bear between the rotor ring and the stator ring at their peripheries to maintain the axial air gap. Also disclosed are wind turbines using these generators, and structures and methods for mounting direct drive rotating electrical generators to the hubs of wind turbines. In particular, the rotor ring of the generator may be carried directly by the hub of a wind turbine to rotate relative to a shaft without being mounted directly to the shaft.

  3. Study of axial magnetic effect

    SciTech Connect

    Braguta, Victor; Chernodub, M. N.; Goy, V. A.; Landsteiner, K.; Ulybyshev, M.

    2016-01-22

    The Axial Magnetic Effect manifests itself as an equilibrium energy flow of massless fermions induced by the axial (chiral) magnetic field. Here we study the Axial Magnetic Effect in the quenched SU(2) lattice gauge theory with massless overlap fermions at finite temperature. We numerically observe that in the low-temperature hadron phase the effect is absent due to the quark confinement. In the high-temperature deconfinement phase the energy flow is an increasing function of the temperature which reaches the predicted asymptotic T{sup 2} behavior at high temperatures. We find, however, that energy flow is about one order of magnitude lower compared to a theoretical prediction.

  4. Appropriate management of axial spondyloarthritis.

    PubMed

    LaSalle, Sean P; Deodhar, Atul A

    2007-10-01

    The management of axial spondyloarthritis includes a structured baseline assessment of the disease and follow-up of treatment efficacy using validated instruments. The treatment will depend on the severity and predominant manifestations of the disease. The cornerstone of management remains physical therapy and nonsteroidal anti-inflammatory drugs. Disease-modifying antirheumatic drugs such as sulfasalazine have shown efficacy only in treating peripheral arthritis, whereas thalidomide and pamidronate have shown some efficacy in treating axial inflammation. Anti-tumor necrosis factor-alpha agents are an efficacious option for treating signs and symptoms of axial disease, peripheral arthritis, and enthesitis, and for improving functional outcomes. They have not shown efficacy in reducing radiographic progression in axial disease. Recent evidence suggests that the new bone formation in ankylosing spondylitis may be due to upregulation of Wnt signaling in the osteoblastic pathway secondary to low serum DKK-1 levels, which are further suppressed by tumor necrosis factor inhibitor therapy.

  5. Twin-Axial Wire Antenna

    DTIC Science & Technology

    2015-08-06

    08-2015 Publication Twin-Axial Wire Antenna David A. Tonn Naval Under Warfare Center Division, Newport 1176 Howell St., Code 00L, Bldg 102T...Approved for Public Release Distribution is unlimited Attorney Docket No. 300030 1 of 10 TWIN-AXIAL WIRE ANTENNA STATEMENT OF GOVERNMENT INTEREST...2 of 10 length of the antenna wire . This creates a high pass filter in the antenna and prevents current flow in the VLF/LF bands. [0005] U.S

  6. Dissipative axial inflation

    NASA Astrophysics Data System (ADS)

    Notari, Alessio; Tywoniuk, Konrad

    2016-12-01

    We analyze in detail the background cosmological evolution of a scalar field coupled to a massless abelian gauge field through an axial term phi/fγ F ~F, such as in the case of an axion. Gauge fields in this case are known to experience tachyonic growth and therefore can backreact on the background as an effective dissipation into radiation energy density ρR, which can lead to inflation without the need of a flat potential. We analyze the system, for momenta k smaller than the cutoff fγ, including the backreaction numerically. We consider the evolution from a given static initial condition and explicitly show that, if fγ is smaller than the field excursion phi0 by about a factor of at least Script O (20), there is a friction effect which turns on before the field can fall down and which can then lead to a very long stage of inflation with a generic potential. In addition we find superimposed oscillations, which would get imprinted on any kind of perturbations, scalars and tensors. Such oscillations have a period of 4-5 efolds and an amplitude which is typically less than a few percent and decreases linearly with fγ. We also stress that the curvature perturbation on uniform density slices should be sensitive to slow-roll parameters related to ρR rather than dot phi2/2 and we discuss the existence of friction terms acting on the perturbations, although we postpone a calculation of the power spectrum and of non-gaussianity to future work and we simply define and compute suitable slow roll parameters. Finally we stress that this scenario may be realized in the axion case, if the coupling 1/fγ to U(1) (photons) is much larger than the coupling 1/fG to non-abelian gauge fields (gluons), since the latter sets the range of the potential and therefore the maximal allowed phi0~ fG.

  7. Differential occupation of axial morphospace.

    PubMed

    Ward, Andrea B; Mehta, Rita S

    2014-02-01

    The postcranial system is composed of the axial and appendicular skeletons. The axial skeleton, which consists of serially repeating segments commonly known as vertebrae, protects and provides leverage for movement of the body. Across the vertebral column, much numerical and morphological diversity can be observed, which is associated with axial regionalization. The present article discusses this basic diversity and the early developmental mechanisms that guide vertebral formation and regionalization. An examination of vertebral numbers across the major vertebrate clades finds that actinopterygian and chondrichthyan fishes tend to increase vertebral number in the caudal region whereas Sarcopterygii increase the number of vertebrae in the precaudal region, although exceptions to each trend exist. Given the different regions of axial morphospace that are occupied by these groups, differential developmental processes control the axial patterning of actinopterygian and sarcopterygian species. It is possible that, among a variety of factors, the differential selective regimes for aquatic versus terrestrial locomotion have led to the differential use of axial morphospace in vertebrates.

  8. CT Colonography (Virtual Colonoscopy)

    MedlinePlus

    ... Z CT Colonography Computed tomography (CT) colonography or virtual colonoscopy uses special x-ray equipment to examine ... and blood vessels. CT colonography, also known as virtual colonoscopy, uses low dose radiation CT scanning to ...

  9. [Application of computed tomography (CT) examination for forensic medicine].

    PubMed

    Urbanik, Andrzej; Chrzan, Robert

    2013-01-01

    The aim of the study is to present a own experiences in usage of post mortem CT examination for forensic medicine. With the help of 16-slice CT scanner 181 corpses were examined. Obtained during acquisition imaging data are later developed with dedicated programmes. Analyzed images were extracted from axial sections, multiplanar reconstructions as well as 3D reconstructions. Gained information helped greatly when classical autopsy was performed by making it more accurate. A CT scan images recorded digitally enable to evaluate corpses at any time, despite processes of putrefaction or cremation. If possible CT examination should precede classical autopsy.

  10. Axial-Centrifugal Compressor Program

    DTIC Science & Technology

    1975-10-01

    We also wish to thank Robert Langworthy of the Eustis Directorate for his timely assistance and constructive guidance. 3, INj TABLE OF CONTENTS Page...34 PREFACE 3 LIST OF ILLUSTRATIONS ..................... 7 LIST OF TABLES . . . . . . . . . . . . . . . . . . . . . . . . . 17 INTRODUCTIONB...Blow Test. 132 Axial IGV Blow Test . . . . . . . . ........... 141 PMIZ ?crn AM BLANK-NOT 1=43D TABLE OF CONTENTS - Continued Centrifugal Compressor

  11. Axial pumps for propulsion systems

    NASA Technical Reports Server (NTRS)

    Huppert, M. C.; Rothe, K.

    1974-01-01

    The development of axial flow hydrogen pumps is examined. The design features and the performance data obtained during the course of the development programs are discussed. The problems created by the pump characteristics are analyzed. Graphs of four stage pump performance for various turbine blade configurations are developed. The characteristics and performance of a variety of pumps are included.

  12. Axial structure of the nucleon

    SciTech Connect

    Veronique Bernard; Latifa Elouadrhiri; Ulf-G Meissner

    2002-01-01

    We review the current status of experimental and theoretical understanding of the axial nucleon structure at low and moderate energies. Topics considered include (quasi)elastic (anti)neutrino-nucleon scattering, charged pion electroproduction off nucleons and ordinary as well as radiative muon capture on the proton.

  13. Thermophoresis of Axially Symmetric Bodies

    DTIC Science & Technology

    2007-11-02

    Sweden Abstract. Thermophoresis of axially symmetric bodies is investigated to first order in the Knudsen-mimber, Kn. The study is made in the limit...derived. Asymptotic solutions are studied. INTRODUCTION Thermophoresis as a phenomenon has been known for a long time, and several authors have approached

  14. Postmortem pulmonary CT in hypothermia.

    PubMed

    Schweitzer, Wolf; Thali, Michael; Giugni, Giannina; Winklhofer, Sebastian

    2014-12-01

    Fatal hypothermia has been associated with pulmonary edema. With postmortem full body computed tomography scanning (PMCT), the lungs can also be examined for CT attenuation. In fatal hypothermia cases low CT attenuation appeared to prevail in the lungs. We compared 14 cases of fatal hypothermia with an age-sex matched control group. Additionally, 4 cases of carbon monoxide (CO) poisoning were examined. Furthermore, 10 test cases were examined to test predictability based on PMCT. Two readers measured CT attenuation on four different axial slices across the lungs (blinded to case group and other reader's results). Hypothermia was associated with statistically significantly lower lung PMCT attenuation and lower lung weights than controls, and there was a dose-effect relationship at an environmental temperature cutoff of 2 °C. CO poisoning yielded low pulmonary attenuation but higher lung weights. General model based prediction yielded a 94% probability for fatal hypothermia deaths and a 21% probability for non-hypothermia deaths in the test group. Increased breathing rate is known to accompany both CO poisoning and hypothermia, so this could partly explain the low PMCT lung attenuation due to an oxygen dissociation curve left shift. A more marked distension in fatal hypothermia, compared to CO poisoning, indicates that further, possibly different mechanisms, are involved in these cases. Increased dead space and increased stiffness to deflation (but not inflation) appear to be effects of inhaling cold air (but not CO) that may explain the difference in low PMCT attenuation seen in hypothermia cases.

  15. Abdominal CT scan

    MedlinePlus

    Computed tomography scan - abdomen; CT scan - abdomen; CT abdomen and pelvis ... 2016:chap 133. Radiologyinfo.org. Computed tomography (CT) - abdomen and pelvis. Updated June 16, 2016. www.radiologyinfo. ...

  16. Computed Tomography (CT) - Spine

    MedlinePlus

    ... test used to help diagnose—or rule out—spinal column damage in injured patients. CT scanning is fast, ... CT is to detect—or to rule out—spinal column damage in patients who have been injured. CT ...

  17. [Axial spondyloarthritis and ankylosing spondylitis].

    PubMed

    Nordström, Dan; Kauppi, Markku

    2010-01-01

    Current classification criteria for ankylosing spondylitis do not allow diagnosis before radiographic changes are visible in sacroiliacal joints. The the new axial spondyloarthropathy (SpA) criteria include axial SpA without radiographic changes as well as established ankylosing spondylitis, recognizing them as a continuum of the same disease. This is of major importance as the burden of early SpA is comparable to that of later stage disease. Diagnosis relies on inflammatory MRI findings which is the most significant change compared to earlier criteria. Emerging data on the efficacy of tumor necrosis factor (TNF) alpha blocking therapies already in early but also in established disease have given new promising alternatives for treatment of this often very cumbersome disease, that rarely responds to classic DMARDs.

  18. Classification of CT-brain slices based on local histograms

    NASA Astrophysics Data System (ADS)

    Avrunin, Oleg G.; Tymkovych, Maksym Y.; Pavlov, Sergii V.; Timchik, Sergii V.; Kisała, Piotr; Orakbaev, Yerbol

    2015-12-01

    Neurosurgical intervention is a very complicated process. Modern operating procedures based on data such as CT, MRI, etc. Automated analysis of these data is an important task for researchers. Some modern methods of brain-slice segmentation use additional data to process these images. Classification can be used to obtain this information. To classify the CT images of the brain, we suggest using local histogram and features extracted from them. The paper shows the process of feature extraction and classification CT-slices of the brain. The process of feature extraction is specialized for axial cross-section of the brain. The work can be applied to medical neurosurgical systems.

  19. Cervical neural foramina: Correlation of microtomy and CT anatomy

    SciTech Connect

    Pech, P.; Daniels, D.L.; Williams, A.L.; Haughton, V.M.

    1985-04-01

    The CT appearance of the cervical neural foramina and contents is described in detail. Nineteen cervical spine specimens were studied with CT and corresponding cryomicrotomy in direct axial, sagittal, coronal, and oblique planes. Both ventra and dorsal nerve roots can be identified in the foramen's lower portion at or below the disk level. The dorsal nerve roots and ganglion contact the superior facet. The ventral nerve roots contact the uncinate process and bottom of the neural foramen. The ventral nerve roots, dorsal nerve roots and ganglion, and vertebral artery are resolved with current high-resolution CT.

  20. Golimumab for treatment of axial spondyloarthritis.

    PubMed

    Rios Rodriguez, Valeria; Poddubnyy, Denis

    2016-02-01

    Axial spondyloarthritis comprises two forms: nonradiographic (nonradiographic axial spondyloarthritis) and radiographic (better known as ankylosing spondylitis), which are often considered as two stages of one disease. Historically, all currently available TNF-α inhibitors were first investigated in ankylosing spondylitis and later on in nonradiographic axial spondyloarthritis. This year, EMA has granted golimumab approval for the treatment of active nonradiographic axial spondyloarthritis based on the recently published data from the GO-AHEAD study. This article summarizes recent data on efficacy and safety of golimumab in the treatment of ankylosing spondylitis and nonradiographic axial spondyloarthritis.

  1. Fast CT-CT fluoroscopy registration with respiratory motion compensation for image-guided lung intervention

    NASA Astrophysics Data System (ADS)

    Su, Po; Xue, Zhong; Lu, Kongkuo; Yang, Jianhua; Wong, Stephen T.

    2012-02-01

    CT-fluoroscopy (CTF) is an efficient imaging method for guiding percutaneous lung interventions such as biopsy. During CTF-guided biopsy procedure, four to ten axial sectional images are captured in a very short time period to provide nearly real-time feedback to physicians, so that they can adjust the needle as it is advanced toward the target lesion. Although popularly used in clinics, this traditional CTF-guided intervention procedure may require frequent scans and cause unnecessary radiation exposure to clinicians and patients. In addition, CTF only generates limited slices of images and provides limited anatomical information. It also has limited response to respiratory movements and has narrow local anatomical dynamics. To better utilize CTF guidance, we propose a fast CT-CTF registration algorithm with respiratory motion estimation for image-guided lung intervention using electromagnetic (EM) guidance. With the pre-procedural exhale and inhale CT scans, it would be possible to estimate a series of CT images of the same patient at different respiratory phases. Then, once a CTF image is captured during the intervention, our algorithm can pick the best respiratory phase-matched 3D CT image and performs a fast deformable registration to warp the 3D CT toward the CTF. The new 3D CT image can be used to guide the intervention by superimposing the EM-guided needle location on it. Compared to the traditional repetitive CTF guidance, the registered CT integrates both 3D volumetric patient data and nearly real-time local anatomy for more effective and efficient guidance. In this new system, CTF is used as a nearly real-time sensor to overcome the discrepancies between static pre-procedural CT and the patient's anatomy, so as to provide global guidance that may be supplemented with electromagnetic (EM) tracking and to reduce the number of CTF scans needed. In the experiments, the comparative results showed that our fast CT-CTF algorithm can achieve better registration

  2. Friction Reduction for Microhole CT Drilling

    SciTech Connect

    Ken Newman; Patrick Kelleher; Edward Smalley

    2007-03-31

    The objective of this 24 month project focused on improving microhole coiled tubing drilling bottom hole assembly (BHA) reliability and performance, while reducing the drilling cost and complexity associated with inclined/horizontal well sections. This was to be accomplished by eliminating the need for a downhole drilling tractor or other downhole coiled tubing (CT) friction mitigation techniques when drilling long (>2,000 ft.) of inclined/horizontal wellbore. The technical solution to be developed and evaluated in this project was based on vibrating the coiled tubing at surface to reduce the friction along the length of the downhole CT drillstring. The Phase 1 objective of this project centered on determining the optimum surface-applied vibration system design for downhole CT friction mitigation. Design of the system would be based on numerical modeling and laboratory testing of the CT friction mitigation achieved with various types of surface-applied vibration. A numerical model was developed to predict how far downhole the surface-applied vibration would travel. A vibration test fixture, simulating microhole CT drilling in a horizontal wellbore, was constructed and used to refine and validate the numerical model. Numerous tests, with varying surface-applied vibration parameters were evaluated in the vibration test fixture. The data indicated that as long as the axial force on the CT was less than the helical buckling load, axial vibration of the CT was effective at mitigating friction. However, surface-applied vibration only provided a small amount of friction mitigation as the helical buckling load on the CT was reached or exceeded. Since it would be impractical to assume that routine field operations be conducted at less than the helical buckling load of the CT, it was determined that this technical approach did not warrant the additional cost and maintenance issues that would be associated with the surface vibration equipment. As such, the project was

  3. PWR AXIAL BURNUP PROFILE ANALYSIS

    SciTech Connect

    J.M. Acaglione

    2003-09-17

    The purpose of this activity is to develop a representative ''limiting'' axial burnup profile for pressurized water reactors (PWRs), which would encompass the isotopic axial variations caused by different assembly irradiation histories, and produce conservative isotopics with respect to criticality. The effect that the low burnup regions near the ends of spent fuel have on system reactivity is termed the ''end-effect''. This calculation will quantify the end-effects associated with Pressurized Water Reactor (PWR) fuel assemblies emplaced in a hypothetical 21 PWR waste package. The scope of this calculation covers an initial enrichment range of 3.0 through 5.0 wt% U-235 and a burnup range of 10 through 50 GWd/MTU. This activity supports the validation of the process for ensuring conservative generation of spent fuel isotopics with respect to criticality safety applications, and the use of burnup credit for commercial spent nuclear fuel. The intended use of these results will be in the development of PWR waste package loading curves, and applications involving burnup credit. Limitations of this evaluation are that the limiting profiles are only confirmed for use with the B&W 15 x 15 fuel assembly design. However, this assembly design is considered bounding of all other typical commercial PWR fuel assembly designs. This calculation is subject to the Quality Assurance Requirements and Description (QARD) because this activity supports investigations of items or barriers on the Q-list (YMP 2001).

  4. Extra-Axial Cavernous Hemangioma

    PubMed Central

    Kanaan, Imad; Jallu, Ashraf; Alwatban, Jehad; Patay, Zoltan; Hessler, Richard

    2001-01-01

    Two patients with extra-axial cavernous hemangioma who presented with headache and oculovisual disturbances were investigated with computed tomography and magnetic resonance imaging. The lesions masqueraded as basal meningioma, but this diagnosis was not supported by magnetic resonance spectroscopy in one patient. Cerebral angiography with embolization was indicated in one patient, but embolization was not justified in the other. Both patients underwent a pterional craniotomy. The lesions were extradural and highly vascular, necessitating excessive transfusion in one patient in whom gross total resection was achieved, and precluding satisfactory removal in the other. There was no mortality. Transient ophthalmoplegia, the only complication in one patient, was due to surgical manipulation of the cavernous sinus; it resolved progressively over 3 months. Extra-axial skull base cavernous hemangiomas are distinct entities with clinical and radiological characteristics that differ from those of intraparenchymal cavernous malformations. They can mimic meningiomas or pituitary tumors. In some cases, magnetic resonance spectroscopy may narrow the differential diagnoses. Surgical resection remains the treatment of choice, facilitated by preoperative embolization to reduce intraoperative bleeding and by the application of the principles of skull base surgery. Fractionated radiotherapy is an alternative in partial or difficult resections and in high-risk and elderly patients. ImagesFigure 1Figure 2Figure 3Figure 4 PMID:17167631

  5. System Study for Axial Vane Engine Technology

    NASA Technical Reports Server (NTRS)

    Badley, Patrick R.; Smith, Michael R.; Gould, Cedric O.

    2008-01-01

    The purpose of this engine feasibility study was to determine the benefits that can be achieved by incorporating positive displacement axial vane compression and expansion stages into high bypass turbofan engines. These positive-displacement stages would replace some or all of the conventional compressor and turbine stages in the turbine engine, but not the fan. The study considered combustion occurring internal to an axial vane component (i.e., Diesel engine replacing the standard turbine engine combustor, burner, and turbine); and external continuous flow combustion with an axial vane compressor and an axial vane turbine replacing conventional compressor and turbine systems.

  6. Resolution of axial shear strain elastography

    NASA Astrophysics Data System (ADS)

    Thitaikumar, Arun; Righetti, Raffaella; Krouskop, Thomas A.; Ophir, Jonathan

    2006-10-01

    The technique of mapping the local axial component of the shear strain due to quasi-static axial compression is defined as axial shear strain elastography. In this paper, the spatial resolution of axial shear strain elastography is investigated through simulations, using an elastically stiff cylindrical lesion embedded in a homogeneously softer background. Resolution was defined as the smallest size of the inclusion for which the strain value at the inclusion/background interface was greater than the average of the axial shear strain values at the interface and inside the inclusion. The resolution was measured from the axial shear strain profile oriented at 45° to the axis of beam propagation, due to the absence of axial shear strain along the normal directions. The effects of the ultrasound system parameters such as bandwidth, beamwidth and transducer element pitch along with signal processing parameters such as correlation window length (W) and axial shift (ΔW) on the estimated resolution were investigated. The results show that the resolution (at 45° orientation) is determined by the bandwidth and the beamwidth. However, the upper bound on the resolution is limited by the larger of the beamwidth and the window length, which is scaled inversely to the bandwidth. The results also show that the resolution is proportional to the pitch and not significantly affected by the axial window shift.

  7. Axial cylinder internal combustion engine

    SciTech Connect

    Gonzalez, C.

    1992-03-10

    This patent describes improvement in a barrel type internal combustion engine including an engine block having axial-positioned cylinders with reciprocating pistons arranged in a circular pattern: a drive shaft concentrically positioned within the cylinder block having an offset portion extending outside the cylinder block; a wobble spider rotatably journaled to the offset portion; connecting rods for each cylinder connecting each piston to the wobble spider. The improvement comprising: a first sleeve bearing means supporting the drive shaft in the engine block in a cantilevered manner for radial loads; a second sleeve bearing means rotatably supporting the wobble spider on the offset portion of the drive shaft for radial loads; a first roller bearing means positioned between the offset portion of the drive shaft and the wobble spider carrying thrust loadings only; a second roller bearing means carrying thrust loads only reacting to the first roller bearing located on the opposite end of the driveshaft between the shaft and the engine block.

  8. Axially grooved heat pipe study

    NASA Technical Reports Server (NTRS)

    1977-01-01

    A technology evaluation study on axially grooved heat pipes is presented. The state-of-the-art is reviewed and present and future requirements are identified. Analytical models, the Groove Analysis Program (GAP) and a closed form solution, were developed to facilitate parametric performance evaluations. GAP provides a numerical solution of the differential equations which govern the hydrodynamic flow. The model accounts for liquid recession, liquid/vapor shear interaction, puddle flow as well as laminar and turbulent vapor flow conditions. The closed form solution was developed to reduce computation time and complexity in parametric evaluations. It is applicable to laminar and ideal charge conditions, liquid/vapor shear interaction, and an empirical liquid flow factor which accounts for groove geometry and liquid recession effects. The validity of the closed form solution is verified by comparison with GAP predictions and measured data.

  9. Unsteady Flows in Axial Turbomachines

    NASA Technical Reports Server (NTRS)

    Marble, F. E.; Rannie, W. D.

    1957-01-01

    Of the various unsteady flows that occur in axial turbomachines certain asymmetric disturbances, of wave length large in comparison with blade spacing, have become understood to a certain extent. These disturbances divide themselves into two categories: self-induced oscillations and force disturbances. A special type of propagating stall appears as a self-induced disturbance; an asymmetric velocity profile introduced at the compressor inlet constitutes a forced disturbance. Both phenomena have been treated from a unified theoretical point of view in which the asymmetric disturbances are linearized and the blade characteristics are assumed quasi-steady. Experimental results are in essential agreement with this theory wherever the limitations of the theory are satisfied. For the self-induced disturbances and the more interesting examples of the forced disturbances, the dominant blade characteristic is the dependence of total pressure loss, rather than the turning angle, upon the local blade inlet angle.

  10. High-pitch dual-source CT coronary angiography: analysis of the impact on image quality of altered electrocardiography waves during data acquisition.

    PubMed

    Wang, Xiaoling; Fang, Jiliang; Tong, Haibin; Zhao, Qing; Song, Qingqiao; Luo, Ping; Xue, Chao; Zhang, Min; Yang, Shuhua; Wang, Qun; Wang, Ping; Shi, Fengxiang; Xu, Lei; Rong, Peijing

    2012-06-01

    Electrocardiography (ECG) "altered waves" sometimes occur during data acquisition when computed tomography coronary angiography (CTCA) is performed with the prospectively ECG-triggered high-pitch (Flash spiral) mode using a second-generation dual-source CT. The aim of this study was to assess the effect of the ECG altered waves on image quality. Seventy-three consecutive patients with stable sinus rhythm ≤ 65 beats per minute were retrospectively enrolled in this study. CTCA was performed using the Flash spiral mode in which the data acquisition was prospectively triggered at 60 % of the R-R interval and completed within one cardiac cycle. The ECG waves before and during data acquisition were analyzed for grouping purposes. Image quality was evaluated using a four-point scale (1 = best, 4 = unevaluatable). Thirty patients (group 1) were found to have ECG altered waves during data acquisition, while 43 patients (group 2) had ECG "stable waves." The altered waves were seen as the baseline drifting; the broad, erected, or inverted P wave or QRS complexes; and a new wave. However, the length of the R-R interval did not change during the data acquisition. There were no significant differences in image quality scores between the two groups on the per-patient (2 ± 0.87 vs. 2.2 ± 0.74, P = 0.273) or per-segment (1.27 ± 0.54 vs. 1.32 ± 0.55, P = 0.577) basis. There were no significant differences in coronary evaluatability as well (per-patient; 93.3 vs. 95.3 %, P = 0.352; per-segment; 99.4 vs. 99.6 %, P = 1.0). CTCA image quality is not affected by ECG altered waves during data acquisition using the Flash spiral mode in low and stable heart rate patients. Thus, the ECG altered waves are considered artifacts.

  11. NETL CT Imaging Facility

    ScienceCinema

    None

    2016-07-12

    NETL's CT Scanner laboratory is equipped with three CT scanners and a mobile core logging unit that work together to provide characteristic geologic and geophysical information at different scales, non-destructively.

  12. Body CT (CAT Scan)

    MedlinePlus

    ... may increase the risk of an unusual adverse effect. Women should always inform their physician and the CT ... of data to create two-dimensional cross-sectional images of your body, which are then displayed on a monitor. CT ...

  13. Liquid rocket engine axial-flow turbopumps

    NASA Technical Reports Server (NTRS)

    Scheer, D. D.; Huppert, M. C.; Viteri, F.; Farquhar, J.; Keller, R. B., Jr. (Editor)

    1978-01-01

    The axial pump is considered in terms of the total turbopump assembly. Stage hydrodynamic design, pump rotor assembly, pump materials for liquid hydrogen applications, and safety factors as utilized in state of the art pumps are among the topics discussed. Axial pump applications are included.

  14. Axial interaction free-electron laser

    DOEpatents

    Carlsten, B.E.

    1997-09-02

    Electron orbits from a helical axial wiggler in an axial guide field are absolutely unstable as power is extracted from the particles. For off-axis beams an axial FEL mechanism exists when the axial electric field in a TM mode is wiggled to interact with the axial velocity of the electrons that form the beam. The interaction strength is comparable to that for helical FELs and is insensitive to beam orbit errors. The orbits for this mechanism are extremely stable in the absence of space charge and lead to high extraction efficiencies without particle phasing incoherence or interception. This interaction mechanism is suitable for use with intense annular electron beams for high power generation at microwave frequencies. 5 figs.

  15. Axial interaction free-electron laser

    DOEpatents

    Carlsten, Bruce E.

    1997-01-01

    Electron orbits from a helical axial wiggler in an axial guide field are absolutely unstable as power is extracted from the particles. For off-axis beams an axial FEL mechanism exists when the axial electric field in a TM mode is wiggled to interact with the axial velocity of the electrons that form the beam. The interaction strength is comparable to that for helical FELs and is insensitive to beam orbit errors. The orbits for this mechanism are extremely stable in the absence of space charge and lead to high extraction efficiencies without particle phasing incoherence or interception. This interaction mechanism is suitable for use with intense annular electron beams for high power generation at microwave frequencies.

  16. Non-Radiographic Axial Spondyloarthritis.

    PubMed

    Slobodin, Gleb; Eshed, Iris

    2015-12-01

    The term non-radiographic axial spondyloarthritis (nrAxSpA) was coined for patients who have a clinical picture of ankylosing spondylitis (AS) but do not exhibit radiographic sacroiliitis. The ASAS classification criteria for nrAxSpA, ensuring the recruitment of homogenous study cohorts, were accepted in 2009, although the respective diagnostic criteria for daily clinical practice have not yet been developed. The clinical diagnosis should be based on the composite of clinical symptoms and signs of the disease, HLA B27 status, and magnetic resonance imaging (MRI) of sacroiliac joints. Notably, a negative MRI or HLA B27 does not exclude the diagnosis in patients with a high clinical suspicion for nrAxSpA. The prevalence of nrAxSpA is similar to that of AS, but the former has a higher female preponderance. The rate of progression of nrAxSpA to the radiographic stage of disease (AS) ranges from 10% to 20% over 2 years. Current treatment strategies for nrAxSpA are the same as for AS and include non-steroidal anti-inflammatory drugs and inhibitors of tumor necrosis factor-alpha. While this review summarizes the current achievements in the field of nrAxSpA, further understanding of the epidemiology and natural history of the disease and, particularly, mechanisms of inflammation and subsequent new bone formation is essential for the development of new treatment strategies for nrAxSpA patients.

  17. Helical mode lung 4D-CT reconstruction using Bayesian model.

    PubMed

    He, Tiancheng; Xue, Zhong; Nitsch, Paige L; Teh, Bin S; Wong, Stephen T

    2013-01-01

    4D computed tomography (CT) has been widely used for treatment planning of thoracic and abdominal cancer radiotherapy. Current 4D-CT lung image reconstruction methods rely on respiratory gating to rearrange the large number of axial images into different phases, which may be subject to external surrogate errors due to poor reproducibility of breathing cycles. New image-matching-based reconstruction works better for the cine mode of 4D-CT acquisition than the helical mode because the table position of each axial image is different in helical mode and image matching might suffer from bigger errors. In helical mode, not only the phases but also the un-uniform table positions of images need to be considered. We propose a Bayesian method for automated 4D-CT lung image reconstruction in helical mode 4D scans. Each axial image is assigned to a respiratory phase based on the Bayesian framework that ensures spatial and temporal smoothness of surfaces of anatomical structures. Iterative optimization is used to reconstruct a series of 3D-CT images for subjects undergoing 4D scans. In experiments, we compared visually and quantitatively the results of the proposed Bayesian 4D-CT reconstruction algorithm with the respiratory surrogate and the image matching-based method. The results showed that the proposed algorithm yielded better 4D-CT for helical scans.

  18. Strategies to reduce radiation dose in cardiac PET/CT

    NASA Astrophysics Data System (ADS)

    Wu, Tung Hsin; Wu, Nien-Yun; Wang, Shyh-Jen; Wu, Jay; S. P. Mok, Greta; Yang, Ching-Ching; Huang, Tzung-Chi

    2011-08-01

    Our aim was to investigate CT dose reduction strategies on a hybrid PET/CT scanner for cardiac applications.MaterialsImage quality and dose estimation of different CT scanning protocols for CT coronary angiography (CTCA), and CT-based attenuation correction for PET imaging were investigated. Fifteen patients underwent CTCA, perfusion PET imaging at rest and under stress, and FDG PET for myocardial viability. These patients were divided into three groups based on the CTCA technique performed: retrospectively gated helical (RGH), ECG tube current modulation (ETCM), and prospective gated axial (PGA) acquisitions. All emission images were corrected for photon attenuation using CT images obtained by default setting and an ultra-low dose CT (ULDCT) scan.ResultsRadiation dose in RGH technique was 22.2±4.0 mSv. It was reduced to 10.95±0.82 and 4.13±0.31 mSv using ETCM and PGA techniques, respectively. Radiation dose in CT transmission scan was reduced by 96.5% (from 4.53±0.5 to 0.16±0.01 mSv) when applying ULDCT as compared to the default CT. No significant difference in terms of image quality was found among various protocols.ConclusionThe proposed CT scanning strategies, i.e. ETCM or PGA for CTCA and ULDCT for PET attenuation correction, could reduce radiation dose up to 47% without degrading imaging quality in an integrated cardiac PET/CT coronary artery examination.

  19. Axial force measurement for esophageal function testing

    PubMed Central

    Gravesen, Flemming H; Funch-Jensen, Peter; Gregersen, Hans; Drewes, Asbjørn Mohr

    2009-01-01

    The esophagus serves to transport food and fluid from the pharynx to the stomach. Manometry has been the “golden standard” for the diagnosis of esophageal motility diseases for many decades. Hence, esophageal function is normally evaluated by means of manometry even though it reflects the squeeze force (force in radial direction) whereas the bolus moves along the length of esophagus in a distal direction. Force measurements in the longitudinal (axial) direction provide a more direct measure of esophageal transport function. The technique used to record axial force has developed from external force transducers over in-vivo strain gauges of various sizes to electrical impedance based measurements. The amplitude and duration of the axial force has been shown to be as reliable as manometry. Normal, as well as abnormal, manometric recordings occur with normal bolus transit, which have been documented using imaging modalities such as radiography and scintigraphy. This inconsistency using manometry has also been documented by axial force recordings. This underlines the lack of information when diagnostics are based on manometry alone. Increasing the volume of a bag mounted on a probe with combined axial force and manometry recordings showed that axial force amplitude increased by 130% in contrast to an increase of 30% using manometry. Using axial force in combination with manometry provides a more complete picture of esophageal motility, and the current paper outlines the advantages of using this method. PMID:19132762

  20. Flow Split Venturi, Axially-Rotated Valve

    DOEpatents

    Walrath, David E.; Lindberg, William R.; Burgess, Robert K.; LaBelle, James

    2000-02-22

    The present invention provides an axially-rotated valve which permits increased flow rates and lower pressure drop (characterized by a lower loss coefficient) by using an axial eccentric split venturi with two portions where at least one portion is rotatable with respect to the other portion. The axially-rotated valve typically may be designed to avoid flow separation and/or cavitation at full flow under a variety of conditions. Similarly, the valve is designed, in some embodiments, to produce streamlined flow within the valve. An axially aligned outlet may also increase the flow efficiency. A typical cross section of the eccentric split venturi may be non-axisymmetric such as a semicircular cross section which may assist in both throttling capabilities and in maximum flow capacity using the design of the present invention. Such a design can include applications for freeze resistant axially-rotated valves and may be fully-opened and fully-closed in one-half of a complete rotation. An internal wide radius elbow typically connected to a rotatable portion of the eccentric venturi may assist in directing flow with lower friction losses. A valve actuator may actuate in an axial manner yet be uniquely located outside of the axial flow path to further reduce friction losses. A seal may be used between the two portions that may include a peripheral and diametrical seal in the same plane. A seal separator may increase the useful life of the seal between the fixed and rotatable portions.

  1. Comparison of CT and MR in 400 patients with suspected disease of the brain and cervical spinal cord

    SciTech Connect

    Bradley, W.G. Jr.; Waluch, V.; Yadley, R.A.; Wycoff, R.R.

    1984-09-01

    Magnetic resonance imaging (MR) (0.35T) and computed tomography (CT) were compared in 400 consecutive patients with suspected disease of the brain and cervical spinal cord. Of 325 positive diagnoses, MR detected abnormality while CT was normal in 93; MR was more specific in 68; MR and CT gave equivalent information in 129; CT was more specific in 32; and CT was positive while MR was normal in 3. MR was superior to CT in detection of multiple sclerosis, subcortical arteriosclerotic encephalopathy, posterior fossa infarcts and tumors, small extra-axial fluid collections, and cervical syringomyelia. CT was preferable in evaluation of meningiomas and separation of tumor from edema. CT takes less time and may be preferable in patients with acute trauma as well as very young or elderly individuals. Thus the two studies should be considered complementary.

  2. Characterization of multiphase fluid flow during air-sparged hydrocyclone flotation by x-ray CT. Sixteenth quarterly report, 14 May--13 August 1994

    SciTech Connect

    Miller, J.D.

    1994-10-10

    The axial flow reversal was studied using tracer injection and results correlation with x-ray CT and flotation. Effects of dimensionless area ratio and flow rate ratio, percent solids in feed, and inlet pressure on location of surface of zero axial velocity in the ASH were studied. 4 figs.

  3. Modeling axial compression fatigue in fiber ropes

    SciTech Connect

    Hearle, J.W.S.; Hobbs, R.E.; Overington, M.S.; Banfield, S.J.

    1995-12-31

    The modeling of long-term fatigue performance of twisted ropes has been extended to cover axial compression fatigue. This mode of failure has been observed in use and testing of ropes. It is characterized by sharp cooperative kinking of yarns, which leads to flex fatigue breakage of fibers. A model of pipeline buckling was modified to allow for plasticity in bending. An axial and lateral restraints, which influence the buckling, were derived from the existing rope mechanics model. Axial compression was introduced into the total computational model, in order to predict the form of buckling and the consequent fiber failure. An alternative use of the program is simply to detect conditions in which axial compression occurs as an indication of the occurrence of fatigue.

  4. Axial grading of inert matrix fuels

    SciTech Connect

    Recktenwald, G. D.; Deinert, M. R.

    2012-07-01

    Burning actinides in an inert matrix fuel to 750 MWd/kg IHM results in a significant reduction in transuranic isotopes. However, achieving this level of burnup in a standard light water reactor would require residence times that are twice that of uranium dioxide fuels. The reactivity of an inert matrix assembly at the end of life is less than 1/3 of its beginning of life reactivity leading to undesirable radial and axial power peaking in the reactor core. Here we show that axial grading of the inert matrix fuel rods can reduce peaking significantly. Monte Carlo simulations are used to model the assembly level power distributions in both ungraded and graded fuel rods. The results show that an axial grading of uranium dioxide and inert matrix fuels with erbium can reduces power peaking by more than 50% in the axial direction. The reduction in power peaking enables the core to operate at significantly higher power. (authors)

  5. Flat-panel volume CT: fundamental principles, technology, and applications.

    PubMed

    Gupta, Rajiv; Cheung, Arnold C; Bartling, Soenke H; Lisauskas, Jennifer; Grasruck, Michael; Leidecker, Christianne; Schmidt, Bernhard; Flohr, Thomas; Brady, Thomas J

    2008-01-01

    Flat-panel volume computed tomography (CT) systems have an innovative design that allows coverage of a large volume per rotation, fluoroscopic and dynamic imaging, and high spatial resolution that permits visualization of complex human anatomy such as fine temporal bone structures and trabecular bone architecture. In simple terms, flat-panel volume CT scanners can be thought of as conventional multidetector CT scanners in which the detector rows have been replaced by an area detector. The flat-panel detector has wide z-axis coverage that enables imaging of entire organs in one axial acquisition. Its fluoroscopic and angiographic capabilities are useful for intraoperative and vascular applications. Furthermore, the high-volume coverage and continuous rotation of the detector may enable depiction of dynamic processes such as coronary blood flow and whole-brain perfusion. Other applications in which flat-panel volume CT may play a role include small-animal imaging, nondestructive testing in animal survival surgeries, and tissue-engineering experiments. Such versatility has led some to predict that flat-panel volume CT will gain importance in interventional and intraoperative applications, especially in specialties such as cardiac imaging, interventional neuroradiology, orthopedics, and otolaryngology. However, the contrast resolution of flat-panel volume CT is slightly inferior to that of multidetector CT, a higher radiation dose is needed to achieve a comparable signal-to-noise ratio, and a slower scintillator results in a longer scanning time.

  6. High temperature co-axial winding transformers

    NASA Technical Reports Server (NTRS)

    Divan, Deepakraj M.; Novotny, Donald W.

    1993-01-01

    The analysis and design of co-axial winding transformers is presented. The design equations are derived and the different design approaches are discussed. One of the most important features of co-axial winding transformers is the fact that the leakage inductance is well controlled and can be made low. This is not the case in conventional winding transformers. In addition, the power density of co-axial winding transformers is higher than conventional ones. Hence, using co-axial winding transformers in a certain converter topology improves the power density of the converter. The design methodology used in meeting the proposed specifications of the co-axial winding transformer specifications are presented and discussed. The final transformer design was constructed in the lab. Co-axial winding transformers proved to be a good choice for high power density and high frequency applications. They have a more predictable performance compared with conventional transformers. In addition, the leakage inductance of the transformer can be controlled easily to suit a specific application. For space applications, one major concern is the extraction of heat from power apparatus to prevent excessive heating and hence damaging of these units. Because of the vacuum environment, the only way to extract heat is by using a cold plate. One advantage of co-axial winding transformers is that the surface area available to extract heat from is very large compared to conventional transformers. This stems from the unique structure of the co-axial transformer where the whole core surface area is exposed and can be utilized for cooling effectively. This is a crucial issue here since most of the losses are core losses.

  7. Planned Axial Reorientation Investigation on Sloshsat

    NASA Technical Reports Server (NTRS)

    Chato, David J.

    2000-01-01

    This paper details the design and logic of an experimental investigation to study axial reorientation in low gravity. The Sloshsat free-flyer is described. The planned axial reorientation experiments and test matrixes are presented. Existing analytical tools are discussed. Estimates for settling range from 64 to 1127 seconds. The planned experiments are modelled using computational fluid dynamics. These models show promise in reducing settling estimates and demonstrate the ability of pulsed high thrust settling to emulate lower thrust continuous firing.

  8. The Slotted Blade Axial-Flow Blower

    DTIC Science & Technology

    1955-09-01

    YORK 18, NEW YORK w is|’ .THE SLOTTED BLADE AXIAL-FLOW BLOVER AUG 0 1 13941J F Dr. H. E. Sheets, Member ASME Chief Research and Development Engineer ... blades of an axial flow blower. The subject of boundary-layer control has attracted considerable attention in respect to the isolated airfoil (1)1 but... blades . Flow through airfoils displays a region of laminar flow beginning at the leading edge. Further downstream, at approximately the location of the

  9. Split Venturi, Axially-Rotated Valve

    DOEpatents

    Walrath, David E.; Lindberg, William R.; Burgess, Robert K.

    2000-08-29

    The present invention provides an axially-rotated valve which permits increased flow rates and lower pressure drop (characterized by a lower loss coefficient) by using an axial eccentric split venturi with two portions where at least one portion is rotatable with respect to the other portion. The axially-rotated valve typically may be designed to avoid flow separation and/or cavitation at full flow under a variety of conditions. Similarly, the valve is designed, in some embodiments, to produce streamlined flow within the valve. A typical cross section of the eccentric split venturi may be non-axisymmetric such as a semicircular cross section which may assist in both throttling capabilities and in maximum flow capacity using the design of the present invention. Such a design can include applications for freeze resistant axially-rotated valves and may be fully-opened and fully-closed in one-half of a complete rotation. An internal wide radius elbow typically connected to a rotatable portion of the eccentric venturi may assist in directing flow with lower friction losses. A valve actuator may actuate in an axial manner yet be uniquely located outside of the axial flow path to further reduce friction losses. A seal may be used between the two portions that may include a peripheral and diametrical seal in the same plane.

  10. Wave propagation in axially moving periodic strings

    NASA Astrophysics Data System (ADS)

    Sorokin, Vladislav S.; Thomsen, Jon Juel

    2017-04-01

    The paper deals with analytically studying transverse waves propagation in an axially moving string with periodically modulated cross section. The structure effectively models various relevant technological systems, e.g. belts, thread lines, band saws, etc., and, in particular, roller chain drives for diesel engines by capturing both their spatial periodicity and axial motion. The Method of Varying Amplitudes is employed in the analysis. It is shown that the compound wave traveling in the axially moving periodic string comprises many components with different frequencies and wavenumbers. This is in contrast to non-moving periodic structures, for which all components of the corresponding compound wave feature the same frequency. Due to this "multi-frequency" character of the wave motion, the conventional notion of frequency band-gaps appears to be not applicable for the moving periodic strings. Thus, for such structures, by frequency band-gaps it is proposed to understand frequency ranges in which the primary component of the compound wave attenuates. Such frequency band-gaps can be present for a moving periodic string, but only if its axial velocity is lower than the transverse wave speed, and, the higher the axial velocity, the narrower the frequency band-gaps. The revealed effects could be of potential importance for applications, e.g. they indicate that due to spatial inhomogeneity, oscillations of axially moving periodic chains always involve a multitude of frequencies.

  11. Knee CT scan

    MedlinePlus

    CAT scan - knee; Computed axial tomography scan - knee; Computed tomography scan - knee ... scanners can perform the exam without stopping.) A computer makes several images of the body area. These ...

  12. CT angiography - chest

    MedlinePlus

    Computed tomography angiography - thorax; CTA - lungs; Pulmonary embolism - CTA chest; Thoracic aortic aneurysm - CTA chest; Venous thromboembolism - CTA lung; Blood clot - CTA lung; Embolus - CTA lung; CT ...

  13. Computed Tomography (CT) -- Sinuses

    MedlinePlus

    ... More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Computed Tomography (CT) - Sinuses Computed tomography (CT) of the sinuses uses special x-ray equipment to evaluate the paranasal sinus cavities – hollow, air-filled spaces within the bones of the face surrounding the ...

  14. Donkey dental anatomy. Part 1: Gross and computed axial tomography examinations.

    PubMed

    Du Toit, N; Kempson, S A; Dixon, P M

    2008-06-01

    Post-mortem examination of 19 donkey skulls showed that donkeys have a greater degree of anisognathia (27% width difference between upper and lower jaws) compared to horses (23%). Teeth (n=108) were collected from 14 skulls and examined grossly and by computed axial tomography (CAT). A greater degree of peripheral enamel infolding was found in mandibular cheek teeth (CT) compared to maxillary CT (P<0.001). A significant increase in peripheral cementum from the apical region to the clinical crown was demonstrated in all CT (P<0.0001). All donkey CT had at least five pulp cavities with six pulp cavities present in the 06s and 11s. A new endodontic numbering system for equid CT has been proposed. A greater occlusal depth of secondary dentine (mm) was present in older donkeys (>16 years) than in the younger (<15 years) donkeys studied. Based on gross and CAT examinations, donkey dental anatomy was shown to be largely similar to that described in horses.

  15. Optimization of residual heat removal pump axial thrust and axial bearing

    SciTech Connect

    Schubert, F.

    1996-12-01

    The residual heat removal (RHR) pumps of German 1300 megawatt pressurized-water reactor (PWR) power plants are of the single stage end suction type with volute casing or with diffuser and forged circular casing. Due to the service conditions the pumps have to cover the full capacity range as well as a big variation in suction static pressure. This results in a big difference in the axial thrust that has to be borne by the axial bearing. Because these pumps are designed to operate without auxiliary systems (things that do not exist can not fail), they are equipped with antifriction bearings and sump oil lubrication. To minimize the heat production within the bearing casing, a number of PWR plants have pumps with combined axial/radial bearings of the ball type. Due to the fact that the maximum axial thrust caused by static pressure and hydrodynamic forces on the impeller is too big to be borne by that type of axial bearing, the impellers were designed to produce a hydrodynamic axial force that counteracts the static axial force. Thus, the resulting axial thrust may change direction when the static pressure varies.

  16. Axial eye length after retinal detachment surgery.

    PubMed

    Vukojević, Nenad; Sikić, Jakov; Curković, Tihomir; Juratovac, Zlatko; Katusić, Damir; Sarić, Borna; Jukić, Tomislav

    2005-01-01

    Changes in the eye axial diameter were studied to assess the eye globe impact of conventional operation for retinal detachment. The study included 69 eyes in 69 patients operated on for rhegmatogenous retinal detachment. There were 46.4% of men and 53.6% of women, mean age 52.7 (+/- 15.21) years. Results of preoperative and postoperative ultrasonographic measurement of axial diameter are presented. The mean preoperative and postoperative eye axial diameter was 23.69 (+/- 1.84) mm and 24.43 (+/- 1.91) mm, respectively. Postoperative results showed the axial eye length to increase by a mean of 0.74 (+/- 0.44) mm, yielding a statistically significant difference from the preoperative measurement (p < 0.001). The mean myopia induced by this eyeball elongation was 1.77 D. The encircling band with and without segmental buckling used in surgical repair of retinal detachment creates circular and segmental indentation of the eyeball, thus increasing its axial length. The myopia induced by elongation of the eyeball results in considerable myopia, which requires appropriate correction in the early postoperative period to achieve favorable vision rehabilitation.

  17. Axial super-resolution evanescent wave tomography

    NASA Astrophysics Data System (ADS)

    Pendharker, Sarang; Shende, Swapnali; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-12-01

    Optical tomographic reconstruction of a 3D nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography (AxSET) method that enables the use of regular evanescent wave microscopes like Total Internal Reflection Fluorescence Microscope (TIRF) beyond surface imaging, and achieve tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of three-dimensional fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by 1D (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axial resolution of $\\sim$130 nm. Our method does not require any additional optical components or sample preparation. The proposed method can be combined with focal plane super-resolution techniques like STORM and can also be adapted for THz and microwave near-field tomography.

  18. Are axial and radial flow chromatography different?

    PubMed

    Besselink, Tamara; van der Padt, Albert; Janssen, Anja E M; Boom, Remko M

    2013-01-04

    Radial flow chromatography can be a solution for scaling up a packed bed chromatographic process to larger processing volumes. In this study we compared axial and radial flow affinity chromatography both experimentally and theoretically. We used an axial flow column and a miniaturized radial flow column with a ratio of 1.8 between outer and inner surface area, both with a bed height of 5 cm. The columns were packed with affinity resin to adsorb BSA. The average velocity in the columns was set equal. No difference in performance between the two columns could be observed. To gain more insight into the design of a radial flow column, the velocity profile and resin distribution in the radial flow column were calculated. Using mathematical models we found that the breakthrough performance of radial flow chromatography is very similar to axial flow when the ratio between outer and inner radius of the radial flow column is around 2. When this ratio is increased, differences become more apparent, but remain small. However, the ratio does have a significant influence on the velocity profile inside the resin bed, which directly influences the pressure drop and potentially resin compression, especially at higher values for this ratio. The choice between axial and radial flow will be based on cost price, footprint and packing characteristics. For small-scale processes, axial flow chromatography is probably the best choice, for resin volumes of at least several tens of litres, radial flow chromatography may be preferable.

  19. Axial super-resolution evanescent wave tomography.

    PubMed

    Pendharker, Sarang; Shende, Swapnali; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-12-01

    Optical tomographic reconstruction of a three-dimensional (3D) nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography method that enables the use of regular evanescent wave microscopes like the total internal reflection fluorescence microscope beyond surface imaging and achieve a tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of 3D fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by one-dimensional (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axial resolution of ∼130  nm. Our method does not require any additional optical components or sample preparation. The proposed method can be combined with focal plane super-resolution techniques like stochastic optical reconstruction microscopy and can also be adapted for THz and microwave near-field tomography.

  20. Axial flow reversal and its significance in air-sparged hydrocyclone (ASH) flotation

    SciTech Connect

    Miller, J.D.; Das, A.; Yin, D.

    1995-12-31

    In recent years the potential of air-sparged hydrocyclone (ASH) flotation for fine coal cleaning has been demonstrated both in pilot plant testing and in a plant-site demonstration program. Further improvements in the ASH technology will depend, to some extent, on improved understanding of the complex multiphase fluid flow. Froth transport plays a very important role in determining the efficiency of fine coal cleaning by ASH flotation. It should be noted that the surface of zero axial velocity is of particular significance in froth transport because the location of this surface actually accounts for the amount of froth being transported to the overflow. In this regard, the axial flow reversal has been examined based on specially designed tracer experiments. On the basis of these experimental results, modeling efforts were made to characterize the flow pattern in the ASH. The theoretical predictions based on turbulent fluid dynamic considerations were found to describe experimental observations regarding the surface of zero axial velocity. These results that define the surface of zero axial velocity together with froth phase features established from X-ray CT measurements provide an excellent description of the flow characteristics in ASH flotation and explain the effect of various process variables, such as dimensionless area (A*), dimensionless flowrate (Q*), inlet pressure, percent solids, etc., on flotation recovery. On this basis it is expected that further advances in the design and operation of the ASH system can be made, leading to more efficient use of the ASH technology for fine coal cleaning.

  1. Axial resolution enhancement of third harmonic generation microscopy by harmonic focal point axial modulation

    NASA Astrophysics Data System (ADS)

    Mozdoor Dashtabi, Mahdi; Arabanian, Atoosa Sadat; Massudi, Reza

    2017-02-01

    Harmonic focal point axial modulation (h-FPAM) in nonlinear optical microscopy is introduced and used to enhance the axial resolution and the signal to background ratio by modulating the focal point of a beam of femtosecond pulses train along the axial direction and phase sensitively filtering the resulting signals using a lock-in amplifier. Axial resolution enhancement factor of 2.05 is acquired in 2f detection mode for the third harmonic generation microscopy of glass-oil interfaces. This technique also resolves the image interpretation problem of the fundamental harmonic FPAM technique. Moreover, the potential of this technique for axial sectioning is demonstrated by acquiring images from a red blood cell.

  2. CT of lumbar spine disk herniation: correlation with surgical findings

    SciTech Connect

    Firooznia, H.; Benjamin, V.; Kricheff, I.I.; Rafii, M.; Golimbu, C.

    1984-03-01

    Computed tomography (CT) of the lumbar spine was performed with selectively positioned 5-mm-thick axial cross sections to examine each disk level from the top of the neural foramen to the pedicle of the next caudad vertebra. One hundred consecutive patients with 116 surgical disk explorations were reviewed. There was agreement between the CT and surgical findings in 89 patients (104 explorations) in determination of presence or absence of a herniated nucleus pulposus (HNP). Discrepancy occurred in 12 instances (11 patients): two because of incorrect interpretations, five in previously operated patients, three in spondylolisthesis, and two in spinal stenosis. There were 97 true-positives, eight false-negatives, seven true-negatives, and four false-positives. If nine previously operated patients are excluded from the study, then CT was accurate in detection of presence or absence of an HNP in 93% of the disk explorations.

  3. Volumetric applications for spiral CT in the thorax

    NASA Astrophysics Data System (ADS)

    Rubin, Geoffrey D.; Napel, Sandy; Leung, Ann N.

    1994-05-01

    Spiral computed tomography (CT) is a new technique for rapidly acquiring volumetric data within the body. By combining a continuous gantry rotation and table feed, it is possible to image the entire thorax within a single breath-hold. This eliminates the ventilatory misregistration seen with conventional thoracic CT, which can result in small pulmonary lesions being undetected. An additional advantage of a continuous data set is that axial sections can be reconstructed at arbitrary intervals along the spiral path, resulting in the generation of overlapping sections which diminish partial volume effects resulting from lesions that straddle adjacent sections. The rapid acquisition of spiral CT enables up to a 50% reduction in the total iodinated contrast dose required for routine thoracic CT scanning. This can be very important for imaging patients with cardiac and renal diseases and could reduce the cost of thoracic CT scanning. Alternatively, by combining a high flow peripheral intravenous iodinated contrast injection with a spiral CT acquisition, it is possible to obtain images of the vasculature, which demonstrate pulmonary arterial thrombi, aortic aneurysms and dissections, and congenital vascular anomalies in detail previously unattainable without direct arterial access.

  4. Axial flow positive displacement worm gas generator

    NASA Technical Reports Server (NTRS)

    Murrow, Kurt David (Inventor); Giffin, Rollin George (Inventor); Fakunle, Oladapo (Inventor)

    2010-01-01

    An axial flow positive displacement engine has an inlet axially spaced apart and upstream from an outlet. Inner and outer bodies have offset inner and outer axes extend from the inlet to the outlet through first, second, and third sections of a core assembly in serial downstream flow relationship. At least one of the bodies is rotatable about its axis. The inner and outer bodies have intermeshed inner and outer helical blades wound about the inner and outer axes respectively. The inner and outer helical blades extend radially outwardly and inwardly respectively. The helical blades have first, second, and third twist slopes in the first, second, and third sections respectively. The first twist slopes are less than the second twist slopes and the third twist slopes are less than the second twist slopes. A combustor section extends axially downstream through at least a portion of the second section.

  5. Theoretical Determination of Axial Fan Performance

    NASA Technical Reports Server (NTRS)

    Struve, E.

    1943-01-01

    The report presents a method for the computation of axial fan characteristics. The method is based on the assumption that the law of constancy of the circulation along the blade holds, approximately, for all fan conditions for which the blade elements operate at normal angles of attack (up to the stalling angles). Pressure head coefficient K(sub a) and power coefficient K(sub u) for the force components in the axial and tangential directions, respectively, and analogous to the lift and drag coefficients C(sub y) and C(sub x) are conveniently introduced.

  6. Rotor self-lubricating axial stop

    NASA Technical Reports Server (NTRS)

    Blount, Dale H. (Inventor)

    1989-01-01

    A plurality of lubricating plugs are disposed in the stationary backup face adjacent to the axial stop face of a rotating impeller mounted in a turbopump for pumping liquid oxygen or liquid hydrogen. The stop face and the backup face are those surfaces which engage when the axial load on the impeller exceeds the load balancing capability. The plugs have a truncated conical configuration so as to be trapped in the backup face, and are disposed at varying radii on the face to provide complete surface lubrication. The plugs may be formed from Teflon, Kel-F or bronze filled Teflon.

  7. CT Angiography (CTA)

    MedlinePlus

    ... CT Angiography? Angiography is a minimally invasive medical test that helps physicians diagnose and treat medical conditions. Angiography uses one of three imaging technologies and, in most cases, a contrast material injection ...

  8. Computed Tomography (CT) -- Sinuses

    MedlinePlus Videos and Cool Tools

    ... to urinate; however, this is actually a contrast effect and subsides quickly. When you enter the CT scanner room, special light lines may be seen projected onto your body, and are used to ensure that you are ...

  9. Computed Tomography (CT) -- Head

    MedlinePlus Videos and Cool Tools

    ... to urinate; however, this is actually a contrast effect and subsides quickly. When you enter the CT scanner room, special light lines may be seen projected onto your body, and are used to ensure that you are ...

  10. Thoracic spine CT scan

    MedlinePlus

    ... Narrowing of the spine ( spinal stenosis ) Scoliosis Tumor Risks Risks of CT scans include: Exposure to radiation ... urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows ...

  11. Pediatric CT Scans

    Cancer.gov

    The Radiation Epidemiology Branch and collaborators have initiated a retrospective cohort study to evaluate the relationship between radiation exposure from CT scans conducted during childhood and adolescence and the subsequent development of cancer.

  12. Body CT (CAT Scan)

    MedlinePlus

    ... lives. CT has been shown to be a cost-effective imaging tool for a wide range of ... accredited facilities database . This website does not provide cost information. The costs for specific medical imaging tests, ...

  13. Cardiac CT Scan

    MedlinePlus

    ... CT Scan Related Topics Aneurysm Coronary Calcium Scan Coronary Heart Disease Heart Attack Pulmonary Embolism Send a link to ... imaging test can help doctors detect or evaluate coronary heart disease, calcium buildup in the coronary arteries, problems with ...

  14. Co-axial, high energy gamma generator

    DOEpatents

    Reijonen, Jani Petteri; Gicquel, Frederic

    2011-08-16

    A gamma ray generator includes an ion source in a first chamber. A second chamber is configured co-axially around the first chamber at a lower second pressure. Co-axially arranged plasma apertures separate the two chambers and provide for restricted passage of ions and gas from the first to the second chamber. The second chamber is formed by a puller electrode having at least one long channel aperture to draw ions from the first chamber when the puller electrode is subject to an appropriate applied potential. A plurality of electrodes rings in the third chamber in third pressure co-axially surround the puller electrode and have at least one channel corresponding to the at least one puller electrode aperture and plasma aperture. The electrode rings increase the energy of the ions to a selected energy in stages in passing between successive pairs of the electrodes by application of an accelerating voltage to the successive pairs of accelerator electrodes. A target disposed co-axially around the plurality of electrodes receives the beam of accelerated ions, producing gamma rays.

  15. Lenses axial space ray tracing measurement.

    PubMed

    Zhao, Weiqian; Sun, Ruoduan; Qiu, Lirong; Shi, Libo; Sha, Dingguo

    2010-02-15

    In order to achieve the precise measurement of the lenses axial space, a new lenses axial space ray tracing measurement (ASRTM) is proposed based on the geometrical theory of optical image. For an assembled lenses with the given radius of curvature r(n) and refractive index nn of every lens, ASRTM uses the annular laser differential confocal chromatography focusing technique (ADCFT) to achieve the precise focusing at the vertex position P(n) of its inner-and-outer spherical surface Sn and obtain the coordinate z(n) corresponding to the axial movement position of ASRTM objective, and then, uses the ray tracing facet iterative algorithm to precisely determine the vertex position P(n) of every spherical surface by these coordinates z(n), refractive index n(n) and spherical radius r(n), and thereby obtaining the lenses inner axial space d(n). The preliminary experimental results indicate that ASRTM has a relative measurement error of less than 0.02%.

  16. Axial spondyloarthritis: the heart of the matter.

    PubMed

    Gensler, Lianne S

    2015-06-01

    A variety of cardiovascular clinical manifestations have been described in patients with spondyloarthritis, especially in well-established ankylosing spondylitis. These include both structural heart disease, conduction defects and ischemic heart disease. The true prevalence of cardiovascular involvement in patients with axial spondyloarthritis, including non-radiographic disease needs to be further defined.

  17. Aerodynamic Design of Axial Flow Compressors

    NASA Technical Reports Server (NTRS)

    Bullock, R. O. (Editor); Johnsen, I. A.

    1965-01-01

    An overview of 'Aerodynamic systems design of axial flow compressors' is presented. Numerous chapters cover topics such as compressor design, ptotential and viscous flow in two dimensional cascades, compressor stall and blade vibration, and compressor flow theory. Theoretical aspects of flow are also covered.

  18. Investigations on Experimental Impellers for Axial Blowers

    NASA Technical Reports Server (NTRS)

    Encke, W.

    1947-01-01

    A selection of measurements obtained on experimental impellers for axial blowers will be reported. In addition to characteristic curves plotted for low and for high peripheral velocities, proportions and blade sections for six different blower models and remarks on the design of blowers will be presented.

  19. CONFOCAL MICROSCOPY SYSTEM PERFORMANCE: AXIAL RESOLUTION

    EPA Science Inventory

    Abstract

    Confocal Microscopy System Performance: Axial resolution.
    Robert M. Zucker, PhD

    Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Re...

  20. Supersonic axial-flow fan flutter

    NASA Technical Reports Server (NTRS)

    Ramsey, John K.

    1988-01-01

    Lane's (1957) analytical formulation of the unsteady pressure distribution on an oscillating two-dimensional flat plate cascade in supersonic axial flow has been developed into a computer code. This unsteady aerodynamic code has shown good agreement with other published data. This code has also been incorporated into an existing aeroelastic code to analyze the NASA Lewis supersonic through-flow fan design.

  1. Axial type self-bearing motor for axial flow blood pump.

    PubMed

    Okada, Yohji; Masuzawa, Toru; Matsuda, Ken-Ichi; Ohmori, Kunihiro; Yamane, Takashi; Konishi, Yoshiaki; Fukahori, Shinya; Ueno, Satoshi; Kim, Seung-Jong

    2003-10-01

    An axial self-bearing motor is proposed which can drive an axial blood pump without physical contact. It is a functional combination of the bi-directional disc motor and the axial active magnetic bearing, where it actively controls single degree-of-freedom motion, while other motions such as lateral vibration are passively stable. For application to a blood pump, the proposed self-bearing motor has the advantages of simple structure and small size. Through the finite element method (FEM) analysis and the experimental test, its good feasibility is verified. Finally, the axial flow pump is fabricated using the developed magnetically suspended motor. The pump test is carried out and the results are discussed in detail.

  2. Description of Axial Detail for ROK Fuel

    SciTech Connect

    Trellue, Holly R; Galloway, Jack D

    2012-04-20

    For the purpose of NDA simulations of the ROK fuel assemblies, we have developed an axial burnup distribution to represent the pins themselves based on gamma scans of rods in the G23 assembly. For the purpose of modeling the G23 assembly (both at ORNL and LANL), the pin-by-pin burnup map as simulated by ROK is being assumed to represent the radial burnup distribution. However, both DA and NDA results indicate that this simulated estimate is not 100% correct. In particular, the burnup obtained from the axial gamma scan of 7 pins does not represent exactly the same 'average' pin burnup as the ROK simulation. Correction for this discrepancy is a goal of the well-characterized assembly task but will take time. For now, I have come up with a correlation for 26 axial points of the burnup as obtained by gamma scans of 7 different rods (C13, G01, G02, J11, K10, L02, and M04, neglecting K02 at this time) to the average burnup given by the simulation for each of the rods individually. The resulting fraction in each axial zone is then averaged for the 7 different rods so that it can represent every fuel pin in the assembly. The burnup in each of the 26 axial zones of rods in all ROK assemblies will then be directly adjusted using this fraction, which is given in Table 1. Note that the gamma scan data given by ROK for assembly G23 included a length of {approx}3686 mm, so the first 12 mm and the last 14 mm were ignored to give an actual rod length of {approx}366 cm. To represent assembly F02 in which no pin-by-pin burnup distribution is given by ROK, we must model it using infinitely-reflected geometry but can look at the effects of measuring in different axial zones by using intermediate burnup files (i.e. smaller burnups than 28 GWd/MTU) and determining which axial zone(s) each burnup represents. Details for assembly F02 are then given in Tables 2 and 3, which is given in Table 1 and has 44 total axial zones to represent the top meter in explicit detail in addition to the

  3. Review of Axial Burnup Distribution Considerations for Burnup Credit Calculations

    SciTech Connect

    Wagner, J.C.; DeHart, M.D.

    2000-03-01

    This report attempts to summarize and consolidate the existing knowledge on axial burnup distribution issues that are important to burnup credit criticality safety calculations. Recently released Nuclear Regulatory Commission (NRC) staff guidance permits limited burnup credit, and thus, has prompted resolution of the axial burnup distribution issue. The reactivity difference between the neutron multiplication factor (keff) calculated with explicit representation of the axial burnup distribution and keff calculated assuming a uniform axial burnup is referred to as the ``end effect.'' This end effect is shown to be dependent on many factors, including the axial-burnup profile, total accumulated burnup, cooling time, initial enrichment, assembly design, and the isotopics considered (i.e., actinide-only or actinides plus fission products). Axial modeling studies, efforts related to the development of axial-profile databases, and the determination of bounding axial profiles are also discussed. Finally, areas that could benefit from further efforts are identified.

  4. Axial flow positive displacement worm compressor

    NASA Technical Reports Server (NTRS)

    Murrow, Kurt David (Inventor); Giffin, Rollin George (Inventor); Fakunle, Oladapo (Inventor)

    2010-01-01

    An axial flow positive displacement compressor has an inlet axially spaced apart and upstream from an outlet. Inner and outer bodies have offset inner and outer axes extend from the inlet to the outlet through first and second sections of a compressor assembly in serial downstream flow relationship. At least one of the bodies is rotatable about its axis. The inner and outer bodies have intermeshed inner and outer helical blades wound about the inner and outer axes respectively. The inner and outer helical blades extend radially outwardly and inwardly respectively. The helical blades have first and second twist slopes in the first and second sections respectively. The first twist slopes are less than the second twist slopes. An engine including the compressor has in downstream serial flow relationship from the compressor a combustor and a high pressure turbine drivingly connected to the compressor by a high pressure shaft.

  5. Modular organization of axial microcircuits in zebrafish

    PubMed Central

    Bagnall, Martha W.; McLean, David L.

    2014-01-01

    Locomotion requires precise control of spinal networks. In tetrapods and bipeds, dynamic regulation of locomotion is simplified by the modular organization of spinal limb circuits, but it is not known whether their predecessors, fish axial circuits, are similarly organized. Here, we demonstrate that the larval zebrafish spinal cord contains distinct, parallel microcircuits for independent control of dorsal and ventral musculature on each side of the body. During normal swimming, dorsal and ventral microcircuits are equally active; but during postural correction, fish differentially engage these microcircuits to generate torque for self-righting. These findings reveal greater complexity in the axial spinal networks responsible for swimming than previously recognized and suggest an early template of modular organization for more complex locomotor circuits in later vertebrates. PMID:24408436

  6. Buckling of axially compressed conical shells

    NASA Technical Reports Server (NTRS)

    Chang, C.-H.; Katz, L.

    1980-01-01

    The buckling of a truncated elastic conical shell subjected to an axial compression is a classical problem in shell structures. The paper reinvestigates the buckling of an axially compressed truncated conical shell with rigid bulkheads. Two improvements are achieved. First, the condition that the total horizontal displacement must vanish due to rigid bulkhead and axisymmetry is treated as a constraint. This constraint is incorporated into the system through the use of the Lagrange multiplier; then the variational method is used to derive a complete set of boundary conditions for conical shells. Second, the stability is evaluated in the deformed state using the asymptotic solutions of the pair of Donnell-type equations for axisymmetric configuration. The results indicate that the buckling strength of conical shells depends mainly on the condition of the smaller end. In addition to the vertex angle, the distance ratio plays, at least, an equally important role.

  7. Tri-axial tactile sensing element

    NASA Astrophysics Data System (ADS)

    Castellanos-Ramos, Julián.; Navas-González, Rafael; Vidal-Verdú, F.

    2013-05-01

    A 13 x 13 square millimetre tri-axial taxel is presented which is suitable for some medical applications, for instance in assistive robotics that involves contact with humans or in prosthetics. Finite Element Analysis is carried out to determine what structure is the best to obtain a uniform distribution of pressure on the sensing areas underneath the structure. This structure has been fabricated in plastic with a 3D printer and a commercial tactile sensor has been used to implement the sensing areas. A three axis linear motorized translation stage with a tri-axial precision force sensor is used to find the parameters of the linear regression model and characterize the proposed taxel. The results are analysed to see to what extent the goal has been reached in this specific implementation.

  8. The closed co-axial analgesia system.

    PubMed

    Waaben, J; Jørgensen, S; Oxhøj, H; Arnsbo, P

    1980-10-01

    A twin-tube system for nitrous oxide analgesia in dental surgeries is described. The system is a non-polluting modification of the Mapleson A system, employing the principle of co-axial tubing introduced by Bain & Spoerel (1972). Active, continuous and calibrated gas removal takes place via the co-axial tubing by means of an ejector flowmeter. Investigation of the dynamic pressure excursions occurring at the nose-piece are fully compatible with normal breathing. Gas contamination of the dental environment can be reduced by at least 90%. The system described is safe and easy to handle. It is made of light-weight material and is adaptable to the equipment available. No rebreathing takes place when using a fresh gas inflow of 150 ml/kg body weight/min.

  9. Micrometer axial resolution OCT for corneal imaging

    PubMed Central

    Yadav, Rahul; Lee, Kye-Sung; Rolland, Jannick P.; Zavislan, James M.; Aquavella, James V.; Yoon, Geunyoung

    2011-01-01

    An optical coherence tomography (OCT) for high axial resolution corneal imaging is presented. The system uses 375 nm bandwidth (625 to 1000 nm) from a broadband supercontinuum light source. The system was developed in free space to minimize image quality degradation due to dispersion. A custom-designed spectrometer based on a Czerny Turner configuration was implemented to achieve an imaging depth of 1 mm. Experimentally measured axial resolution was 1.1 μm in corneal tissue and had a good agreement with the theoretically calculated resolution from the envelope of the spectral interference fringes. In vivo imaging was carried out and thin corneal layers such as the tear film and the Bowman’s layer were quantified in normal, keratoconus, and contact lens wearing eyes, indicating the system’s suitability for several ophthalmic applications. PMID:22076265

  10. Piping inspection carriage having axially displaceable sensor

    DOEpatents

    Zollinger, W.T.; Treanor, R.C.

    1994-12-06

    A pipe inspection instrument carriage is described for use with a pipe crawler for performing internal inspections of piping surfaces. The carriage has a front leg assembly, a rear leg assembly and a central support connecting the two assemblies and for mounting an instrument arm having inspection instruments. The instrument arm has a Y-arm mounted distally thereon for axially aligning the inspection instrumentation and a mounting block, a linear actuator and axial movement arm for extending the inspection instruments radially outward to operably position the inspection instruments on the piping interior. Also, the carriage has a rotation motor and gear assembly for rotating the central support and the front leg assembly with respect to the rear leg assembly so that the inspection instruments azimuthally scan the piping interior. The instrument carriage allows performance of all piping inspection operations with a minimum of moving parts, thus decreasing the likelihood of performance failure. 4 figures.

  11. Piping inspection carriage having axially displaceable sensor

    DOEpatents

    Zollinger, William T.; Treanor, Richard C.

    1994-01-01

    A pipe inspection instrument carriage for use with a pipe crawler for performing internal inspections of piping surfaces. The carriage has a front leg assembly, a rear leg assembly and a central support connecting the two assemblies and for mounting an instrument arm having inspection instruments. The instrument arm has a y-arm mounted distally thereon for axially aligning the inspection instrumentation and a mounting block, a linear actuator and axial movement arm for extending the inspection instruments radially outward to operably position the inspection instruments on the piping interior. Also, the carriage has a rotation motor and gear assembly for rotating the central support and the front leg assembly with respect to the rear leg assembly so that the inspection instruments azimuthally scan the piping interior. The instrument carriage allows performance of all piping inspection operations with a minimum of moving parts, thus decreasing the likelihood of performance failure.

  12. Microwave axial dielectric properties of carbon fiber

    PubMed Central

    Hong, Wen; Xiao, Peng; Luo, Heng; Li, Zhuan

    2015-01-01

    Randomly distributed carbon fibers (CFs) reinforced epoxy resin composites are prepared by the pouring method, the dielectric properties of CF composites with different fiber content and length have been performed in the frequency range from 8.2 to 12.4 GHz. The complex permittivity of the composite increases with the fiber length, which is attributed to the decrease of depolarization field, and increases with the volume fraction, which is attributed to the increase of polarization. A formula, based on the theory of Reynolds-Hugh, is proposed to calculate the effective permittivity of CF composites, and validated by the experiments. The proposed formula is further applied to derive the axial permittivity of CF and analyze the effect of fiber length on the axial permittivity. PMID:26477579

  13. Compressive strength of axially loaded composite cylinders

    NASA Astrophysics Data System (ADS)

    Kollar, Laszlo P.; Springer, George C.; Spingarn, Jay; McColskey, J. D.

    1993-10-01

    Tests were performed to measure the failure loads of axially compressed glass-fiber-reinforced and graphite-fiber-reinforced composite cylinders. The data were compared with the results of a previous model, which was based on a three-dimensional stress analysis and the Tsai-Wu quadratic first-ply failure criterion. This model predicted the failure loads for glass-fiber-reinforced composites with good accuracy, but less accurately for failure loads of graphite-epoxy composites.

  14. Measurement of axial forces via natural frequency

    NASA Astrophysics Data System (ADS)

    Petro, Samer H.; Reynolds, Don; EnChen, Shen; GangaRao, Hota V. S.

    1998-03-01

    This paper presents results from testing several suspender ropes of the Delaware Memorial Bridge using vibration measurements and a non-destructive evaluation (NDE) instrument called the Axial Load Monitor (ALM). The testing consisted of measuring the frequencies of suspender ropes and determining their tension levels. Results were compared to theoretical predictions. This paper presents the results of the testing and discusses the problems associated with vibration measurements on actual bridges.

  15. Atlanto-axial subluxation: a case report

    PubMed Central

    Thurlow, Robert D

    1988-01-01

    One of the causes of death in rheumatoid patients is cord compression following atlanto-axial subluxation. Dislocations in the cervical spine are common with patients who have rheumatoid arthritis. Anterior subluxation occurs in up to 35%, followed by vertical subluxation in 22.2%, lateral subluxation in 20.6% and rarely posterior subluxation. A case report is presented to illustrate such a complication. ImagesFigure 1Figure 2Figure 3Figure 4

  16. CT of abdominal tuberculosis

    SciTech Connect

    Epstein, B.M.; Mann, J.H.

    1982-11-01

    Intraabdominal tuberculosis (TB) presents with a wide variety of clinical and radiologic features. Besides the reported computed tomographic (CT) finding of high-density ascites in tuberculous peritonitis, this report describes additional CT features highly suggestive of abdominal tuberculosis in eight cases: (1) irregular soft-tissue densities in the omental area; (2) low-density masses surrounded by thick solid rims; (3) a disorganized appearance of soft-tissue densities, fluid, and bowel loops forming a poorly defined mass; (4) low-density lymph nodes with a multilocular appearance after intravenous contrast administration; and (5) possibly high-density ascites. The differential diagnosis of these features include lymphoma, various forms of peritonitis, peritoneal carcinomatosis, and peritoneal mesothelioma. It is important that the CT features of intraabdominal tuberculosis be recognized in order that laparotomy be avoided and less invasive procedures (e.g., laparoscopy, biopsy, or a trial of antituberculous therapy) be instituted.

  17. Bessel beam CARS of axially structured samples

    NASA Astrophysics Data System (ADS)

    Heuke, Sandro; Zheng, Juanjuan; Akimov, Denis; Heintzmann, Rainer; Schmitt, Michael; Popp, Jürgen

    2015-06-01

    We report about a Bessel beam CARS approach for axial profiling of multi-layer structures. This study presents an experimental implementation for the generation of CARS by Bessel beam excitation using only passive optical elements. Furthermore, an analytical expression is provided describing the generated anti-Stokes field by a homogeneous sample. Based on the concept of coherent transfer functions, the underling resolving power of axially structured geometries is investigated. It is found that through the non-linearity of the CARS process in combination with the folded illumination geometry continuous phase-matching is achieved starting from homogeneous samples up to spatial sample frequencies at twice of the pumping electric field wave. The experimental and analytical findings are modeled by the implementation of the Debye Integral and scalar Green function approach. Finally, the goal of reconstructing an axially layered sample is demonstrated on the basis of the numerically simulated modulus and phase of the anti-Stokes far-field radiation pattern.

  18. Bessel beam CARS of axially structured samples.

    PubMed

    Heuke, Sandro; Zheng, Juanjuan; Akimov, Denis; Heintzmann, Rainer; Schmitt, Michael; Popp, Jürgen

    2015-06-05

    We report about a Bessel beam CARS approach for axial profiling of multi-layer structures. This study presents an experimental implementation for the generation of CARS by Bessel beam excitation using only passive optical elements. Furthermore, an analytical expression is provided describing the generated anti-Stokes field by a homogeneous sample. Based on the concept of coherent transfer functions, the underling resolving power of axially structured geometries is investigated. It is found that through the non-linearity of the CARS process in combination with the folded illumination geometry continuous phase-matching is achieved starting from homogeneous samples up to spatial sample frequencies at twice of the pumping electric field wave. The experimental and analytical findings are modeled by the implementation of the Debye Integral and scalar Green function approach. Finally, the goal of reconstructing an axially layered sample is demonstrated on the basis of the numerically simulated modulus and phase of the anti-Stokes far-field radiation pattern.

  19. Golimumab for the treatment of axial spondyloarthritis.

    PubMed

    Gelfer, Gita; Perry, Lisa; Deodhar, Atul

    2016-01-01

    Axial spondyloarthritis (axSpA) is a chronic, immune-mediated inflammatory disease of the axial skeleton that includes ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA). Patients with AS experience chronic pain due to sacroiliac joint and spinal inflammation, and may develop spinal ankylosing with syndesmophyte formation. Tumor necrosis factor α inhibitors (TNFi) have shown promise in the management of AS and axSpA by targeting the underlying inflammatory process, and providing symptomatic relief. Whether they alter the progression of the disease is uncertain. Golimumab is a fully human IgG1 monoclonal antibody that targets and downregulates the pro-inflammatory cytokine TNF-α. The use of golimumab has been shown to reduce the signs and symptoms of axSpA as well as improve patient function and quality reported outcomes. This review focuses on the biological rationale and the results of clinical trials with golimumab for the treatment of axSpA.

  20. Turbulence Effects of Axial Flow Hydrokinetic Turbines

    NASA Astrophysics Data System (ADS)

    Hill, C.; Chamorro, L. P.; Neary, V. S.; Morton, S.; Sotiropoulos, F.

    2011-12-01

    Axial flow hydrokinetic turbines provide a method for extracting the kinetic energy available in unidirectional (river), bidirectional (tidal) and marine currents; however, a deep understanding of the wake dynamics, momentum recovery, geomorphologic effects, and ecological interaction with these hydrokinetic turbines is required to guarantee their economical and environmental viability. The St. Anthony Falls Laboratory (SAFL) at the University of Minnesota (UMN) has performed physical modeling experiments using a 1:10 scale axial flow tidal turbine in the SAFL Main Channel, a 2.75m x 1.8m x 80m open channel test facility. A sophisticated control system allows synchronous measurements of turbine torque and rotational speed along with high resolution 3-D velocity measurements within the channel. Using acoustic Doppler velocimeters (ADVs), high resolution 3-D velocity profile data were collected up to 15 turbine diameters downstream of the turbine location. These data provide valuable information on the wake characteristics (turbulence, Reynolds stresses, etc.) resulting from a rotating axial flow hydrokinetic machine. Regions of high turbulence and shear zones that persist in the near wake regions are delineated along with the velocity deficit and momentum recovery within the wake downstream of the device. Synchronous ADV data shed light on the rotational and meandering characteristics of the wake and its potential impacts on the local geomorphology and hydrodynamic environment. This dataset on single hydrokinetic turbine flow characteristics is the basis for further work on the optimal arrangement and performance environment for arrays of similar hydrokinetic devices.

  1. Vibration of axially loaded circular arches

    SciTech Connect

    Sabir, A.B.; Djoudi, M.S.

    1996-11-01

    The work in the present paper is devoted to the determination of the buckling loads and natural frequencies of axially loaded arch structures. The finite element method is employed using a strain based arch element. The element is based on the conventional Euler curved beam type of strain displacement relationship and satisfies the exact representation of rigid body modes. The sub-space iteration technique is used to determine the eigenvalues and corresponding eigenvectors of the governing transcendental equation. The buckling of a pinned arch subjected to a uniform lateral pressure is first considered. The work is then extended to produce a comprehensive set of results for the vibration of axially loaded arches which are either pinned or fixed at both ends. The first symmetric and anti symmetric modes of vibration are determined and the effect of the axial load on these frequencies is investigated. The practical problem of an arch with a backfill is then considered and the effect of the elastic packing due to this backfill on the natural frequencies is determined.

  2. Bessel beam CARS of axially structured samples

    PubMed Central

    Heuke, Sandro; Zheng, Juanjuan; Akimov, Denis; Heintzmann, Rainer; Schmitt, Michael; Popp, Jürgen

    2015-01-01

    We report about a Bessel beam CARS approach for axial profiling of multi-layer structures. This study presents an experimental implementation for the generation of CARS by Bessel beam excitation using only passive optical elements. Furthermore, an analytical expression is provided describing the generated anti-Stokes field by a homogeneous sample. Based on the concept of coherent transfer functions, the underling resolving power of axially structured geometries is investigated. It is found that through the non-linearity of the CARS process in combination with the folded illumination geometry continuous phase-matching is achieved starting from homogeneous samples up to spatial sample frequencies at twice of the pumping electric field wave. The experimental and analytical findings are modeled by the implementation of the Debye Integral and scalar Green function approach. Finally, the goal of reconstructing an axially layered sample is demonstrated on the basis of the numerically simulated modulus and phase of the anti-Stokes far-field radiation pattern. PMID:26046671

  3. Direct optical nanoscopy with axially localized detection

    NASA Astrophysics Data System (ADS)

    Bourg, N.; Mayet, C.; Dupuis, G.; Barroca, T.; Bon, P.; Lécart, S.; Fort, E.; Lévêque-Fort, S.

    2015-09-01

    Evanescent light excitation is widely used in super-resolution fluorescence microscopy to confine light and reduce background noise. Here, we propose a method of exploiting evanescent light in the context of emission. When a fluorophore is located in close proximity to a medium with a higher refractive index, its near-field component is converted into light that propagates beyond the critical angle. This so-called supercritical-angle fluorescence can be captured using a high-numerical-aperture objective and used to determine the axial position of the fluorophore with nanometre precision. We introduce a new technique for three-dimensional nanoscopy that combines direct stochastic optical reconstruction microscopy (dSTORM) with dedicated detection of supercritical-angle fluorescence emission. We demonstrate that our approach of direct optical nanoscopy with axially localized detection (DONALD) typically yields an isotropic three-dimensional localization precision of 20 nm within an axial range of ∼150 nm above the coverslip.

  4. Wetting on axially-patterned heterogeneous surfaces.

    PubMed

    Rodríguez-Valverde, M A; Ruiz-Cabello, F J Montes; Cabrerizo-Vilchez, M A

    2008-05-19

    Contact angle variability, leading to errors in interpretation, arises from various sources. Contact angle hysteresis (history-dependent wetting) and contact angle multiplicity (corrugation of three-phase contact line) are irrespectively the most frequent causes of this uncertainty. Secondary effects also derived from the distribution of chemical defects on solid surfaces, and so due to the existence of boundaries, are the known "stick/jump-slip" phenomena. Currently, the underlying mechanisms in contact angle hysteresis and their connection to "stick/jump-slip" effects and the prediction of thermodynamic contact angle are not fully understood. In this study, axial models of smooth heterogeneous surface were chosen in order to mitigate contact angle multiplicity. For each axial pattern, advancing, receding and equilibrium contact angles were predicted from the local minima location of the system free energy. A heuristic model, based on the local Young equation for spherical drops on patch-wise axial patterns, was fruitfully tested from the results of free-energy minimization. Despite the very simplistic surface model chosen in this study, it allowed clarifying concepts usually misleading in wetting phenomena.

  5. Dual-energy computed tomography of the head: a phantom study assessing axial dose distribution, eye lens dose, and image noise level

    NASA Astrophysics Data System (ADS)

    Matsubara, Kosuke; Kawashima, Hiroki; Hamaguchi, Takashi; Takata, Tadanori; Kobayashi, Masanao; Ichikawa, Katsuhiro; Koshida, Kichiro

    2016-03-01

    The aim of this study was to propose a calibration method for small dosimeters to measure absorbed doses during dual- source dual-energy computed tomography (DECT) and to compare the axial dose distribution, eye lens dose, and image noise level between DE and standard, single-energy (SE) head CT angiography. Three DE (100/Sn140 kVp 80/Sn140 kVp, and 140/80 kVp) and one SE (120 kVp) acquisitions were performed using a second-generation dual-source CT device and a female head phantom, with an equivalent volumetric CT dose index. The axial absorbed dose distribution at the orbital level and the absorbed doses for the eye lens were measured using radiophotoluminescent glass dosimeters. CT attenuation numbers were obtained in the DE composite images and the SE images of the phantom at the orbital level. The doses absorbed at the orbital level and in the eye lens were lower and standard deviations for the CT attenuation numbers were slightly higher in the DE acquisitions than those in the SE acquisition. The anterior surface dose was especially higher in the SE acquisition than that in the DE acquisitions. Thus, DE head CT angiography can be performed with a radiation dose lower than that required for a standard SE head CT angiography, with a slight increase in the image noise level. The 100/Sn140 kVp acquisition revealed the most balanced axial dose distribution. In addition, our proposed method was effective for calibrating small dosimeters to measure absorbed doses in DECT.

  6. Deformation and failure mechanisms of 18650 battery cells under axial compression

    NASA Astrophysics Data System (ADS)

    Zhu, Juner; Zhang, Xiaowei; Sahraei, Elham; Wierzbicki, Tomasz

    2016-12-01

    An important deformation mode during ground impacts of battery packs made of cylindrical battery cells is axial compression. This type of loading subjects the cell to a complex deformation pattern and failure mechanism. The design of endcaps plays an important role in such deformations. To explore the sequence of deformation and the underlying failure mechanisms, a combined experimental/numerical study was carried out. Tests were conducted on 18650 cells, and the deformation of each component was carefully investigated and documented. There are four different stages in the force-displacement curve, corresponding with deformation of various components in the endcap assembly. A short circuit happens at a displacement of 4 mm. To clarify these observations, a detailed Finite Element model was set up, covering the geometry and the mechanical property of almost all the components of the cell. Using the simulation results, the sequence of the axial compression was revealed, which was subsequently validated by Micro CT scans as well as analytical solutions. Based on the precise analysis of the mechanical behavior, the cause of the short circuit during axial loading was clarified. Two failure mechanisms in the separator at the top section of the cell explain the possible causes of short circuit.

  7. Might axial myofascial properties and biomechanical mechanisms be relevant to ankylosing spondylitis and axial spondyloarthritis?

    PubMed

    Masi, Alfonse T

    2014-01-01

    Ankylosing spondylitis and axial spondyloarthropathy have characteristic age- and sex-specific onset patterns, typical entheseal lesions, and marked heritability, but the integrative mechanisms causing the pathophysiological and structural alterations remain largely undefined. Myofascial tissues are integrated in the body into webs and networks which permit transmission of passive and active tensional forces that provide stabilizing support and help to control movements. Axial myofascial hypertonicity was hypothesized as a potential excessive polymorphic trait which could contribute to chronic biomechanical overloading and exaggerated stresses at entheseal sites. Such a mechanism may help to integrate many of the characteristic host, pathological, and structural features of ankylosing spondylitis and axial spondyloarthritis. Biomechanical stress and strain were recently documented to correlate with peripheral entheseal inflammation and new bone formation in a murine model of spondyloarthritis. Ankylosing spondylitis has traditionally been classified by the modified New York criteria, which require the presence of definite radiographic sacroiliac joint lesions. New classification criteria for axial spondyloarthritis now include patients who do not fulfill the modified New York criteria. The male-to-female sex ratios clearly differed between the two patient categories - 2:1 or 3:1 in ankylosing spondylitis and 1:1 in non-radiographic axial spondyloarthritis - and this suggests a spectral concept of disease and, among females, milder structural alterations. Magnetic resonance imaging of active and chronic lesions in ankylosing spondylitis and axial spondyloarthritis reveals complex patterns, usually interpreted as inflammatory reactions, but shows similarities to acute degenerative disc disease, which attributed to edema formation following mechanical stresses and micro-damage. A basic question is whether mechanically induced microinjury and immunologically mediated

  8. Determination of CT-to-density conversion relationship for image-based treatment planning systems.

    PubMed

    Saw, Cheng B; Loper, Alphonse; Komanduri, Krishna; Combine, Tony; Huq, Saiful; Scicutella, Carol

    2005-01-01

    The implementation of tissue inhomogeneity correction in image-based treatment planning will improve the accuracy of radiation dose calculations for patients undergoing external-beam radiotherapy. Before the tissue inhomogeneity correction can be applied, the relationship between the computed tomography (CT) value and density must be established. This tissue characterization relationship allows the conversion of CT value in each voxel of the CT images into density for use in the dose calculations. This paper describes the proper procedure of establishing the CT value to density conversion relationship. A tissue characterization phantom with 17 inserts made of different materials was scanned using a GE Lightspeed Plus CT scanner (120 kVp). These images were then downloaded into the Eclipse and Pinnacle treatment planning systems. At the treatment planning workstation, the axial images were retrieved to determine the CT value of the inserts. A region of interest was drawn on the central portion of the insert and the mean CT value and its standard deviation were determined. The mean CT value was plotted against the density of the tissue inserts and fitted with bilinear equations. A new set of CT values vs. densities was generated from the bilinear equations and then entered into the treatment planning systems. The need to obtain CT values through the treatment planning system is very clear. The 2 treatment planning systems use different CT value ranges, one from -1024 to 3071 and the other from 0 to 4096. If the range is correct, it would result in inappropriate use of the conversion curve. In addition to the difference in the range of CT values, one treatment planning system uses physical density, while the other uses relative electron density.

  9. CT Perfusion of the Head

    MedlinePlus

    ... the machine as the actual CT scanning is performed. Depending on the type of CT scan, the machine may make several passes. The contrast material will then be injected through an intravenous line ( ...

  10. Axial flow heat exchanger devices and methods for heat transfer using axial flow devices

    DOEpatents

    Koplow, Jeffrey P.

    2016-02-16

    Systems and methods described herein are directed to rotary heat exchangers configured to transfer heat to a heat transfer medium flowing in substantially axial direction within the heat exchangers. Exemplary heat exchangers include a heat conducting structure which is configured to be in thermal contact with a thermal load or a thermal sink, and a heat transfer structure rotatably coupled to the heat conducting structure to form a gap region between the heat conducting structure and the heat transfer structure, the heat transfer structure being configured to rotate during operation of the device. In example devices heat may be transferred across the gap region from a heated axial flow of the heat transfer medium to a cool stationary heat conducting structure, or from a heated stationary conducting structure to a cool axial flow of the heat transfer medium.

  11. Technical aspects of CT angiography.

    PubMed

    Kuszyk, B S; Fishman, E K

    1998-10-01

    The basic tasks of spiral CT acquisition, image processing, and image display are the foundations underlying CT angiography regardless of the anatomic region of interest. Volume rendering is a rapidly emerging image processing technique for creating three-dimensional (3D) images from CT datasets, which has important advantages over other 3D rendering techniques including maximum intensity projection and surface rendering. This articles reviews the techniques that are commonly used in CT angiography and key considerations for optimization.

  12. Seventh-generation CT

    NASA Astrophysics Data System (ADS)

    Besson, G. M.

    2016-03-01

    A new dual-drum CT system architecture has been recently introduced with the potential to achieve significantly higher temporal resolution than is currently possible in medical imaging CT. The concept relies only on known technologies; in particular rotation speeds several times higher than what is possible today could be achieved leveraging typical x-ray tube designs and capabilities. However, the architecture lends itself to the development of a new arrangement of x-ray sources in a toroidal vacuum envelope containing a rotating cathode ring and a (optionally rotating) shared anode ring to potentially obtain increased individual beam power as well as increase total exposure per rotation. The new x-ray source sub-system design builds on previously described concepts and could make the provision of multiple conventional high-power cathodes in a CT system practical by distributing the anode target between the cathodes. In particular, relying on known magnetic-levitation technologies, it is in principle possible to more than double the relative speed of the electron-beam with respect to the target, thus potentially leading to significant individual beam power increases as compared to today's state-of-the-art. In one embodiment, the proposed design can be naturally leveraged by the dual-drum CT concept previously described to alleviate the problem of arranging a number of conventional rotating anode-stem x-ray tubes and power conditioners on the limited space of a CT gantry. In another embodiment, a system with three cathodes is suggested leveraging the architecture previously proposed by Franke.

  13. Drop size selection in axially heated co-axial fiber capillary instability

    NASA Astrophysics Data System (ADS)

    Mowlavi, Saviz; Brun, Pierre-Thomas; Gallaire, Francois

    2015-11-01

    We analyze the sphere size selection mechanism in silicon-in-silica sphere formation through the application of an external axial thermal gradient to a co-axial silicon-in-silica fiber (Gumennik et al., Nature Com., 2013). We first apply a convective/absolute stability analysis to the in-fibre capillary instability governing the sphere formation and demonstrate that the resulting wavelength selection predicts a finite but still too large wavelength. A global stability analysis is then pursued, which accounts for the spatial inhomogeneity of the base flow. F.G. acknowledges funding from ERC SimCoMiCs 280117.

  14. Value of 3-D CT in classifying acetabular fractures during orthopedic residency training.

    PubMed

    Garrett, Jeffrey; Halvorson, Jason; Carroll, Eben; Webb, Lawrence X

    2012-05-01

    The complex anatomy of the pelvis and acetabulum have historically made classification and interpretation of acetabular fractures difficult for orthopedic trainees. The addition of 3-dimensional (3-D) computed tomography (CT) scan has gained popularity in preoperative planning, identification, and education of acetabular fractures given their complexity. Therefore, the authors examined the value of 3-D CT compared with conventional radiography in classifying acetabular fractures at different levels of orthopedic training. Their hypothesis was that 3-D CT would improve correct identification of acetabular fractures compared with conventional radiography.The classic Letournel fracture pattern classification system was presented in quiz format to 57 orthopedic residents and 20 fellowship-trained orthopedic traumatologists. A case consisted of (1) plain radiographs and 2-dimensional axial CT scans or (2) 3-D CT scans. All levels of training showed significant improvement in classifying acetabular fractures with 3-D vs 2-D CT, with the greatest benefit from 3-D CT found in junior residents (postgraduate years 1-3).Three-dimensional CT scans can be an effective educational tool for understanding the complex spatial anatomy of the pelvis, learning acetabular fracture patterns, and correctly applying a widely accepted fracture classification system.

  15. Electronic and optical properties of silicene under uni-axial and bi-axial mechanical strains: A first principle study

    NASA Astrophysics Data System (ADS)

    Mohan, Brij; Kumar, Ashok; Ahluwalia, P. K.

    2014-07-01

    The uni-axial and bi-axial mechanical strain mediated electronic band structures and dielectric properties of silicene have been investigated. It is found that on applying uni- and bi-axial strains, the band gap opens for smaller strain in silicene. However, on further increase of strain beyond 8% silicene changed into metal. The ultimate tensile strength estimated is 3.4 GPa. Imaginary part of dielectric function shows that the inter-band transitions are red-shifted for uni- and bi-axial tensile strains and are blue shifted for uni- and bi-axial compressive strains. Electron energy loss (EEL) function shows that the π+σ plasmon energies are red-shifted for uni- and bi-axial strains and blue-shifted for compressive strains. The π plasmons disappears for tensile and asymmetric strains. Bi-axial asymmetric strain is found to have no influence on inter-band transitions and π+σ plasmon energies.

  16. Scalar resonances in axially symmetric spacetimes

    NASA Astrophysics Data System (ADS)

    Ranea-Sandoval, Ignacio F.; Vucetich, Héctor

    2015-03-01

    We study properties of resonant solutions to the scalar wave equation in several axially symmetric spacetimes. We prove that nonaxial resonant modes do not exist neither in the Lanczos dust cylinder, the extreme (2 + 1) dimensional Bañados-Taitelboim-Zanelli (BTZ) spacetime nor in a class of simple rotating wormhole solutions. Moreover, we find unstable solutions to the wave equation in the Lanczos dust cylinder and in the r2 < 0 region of the extreme (2 + 1) dimensional BTZ spacetime, two solutions that possess closed timelike curves. Similarities with previous results obtained for the Kerr spacetime are explored.

  17. Axial Tomography from Digitized Real Time Radiography

    DOE R&D Accomplishments Database

    Zolnay, A. S.; McDonald, W. M.; Doupont, P. A.; McKinney, R. L.; Lee, M. M.

    1985-01-18

    Axial tomography from digitized real time radiographs provides a useful tool for industrial radiography and tomography. The components of this system are: x-ray source, image intensifier, video camera, video line extractor and digitizer, data storage and reconstruction computers. With this system it is possible to view a two dimensional x-ray image in real time at each angle of rotation and select the tomography plane of interest by choosing which video line to digitize. The digitization of a video line requires less than a second making data acquisition relatively short. Further improvements on this system are planned and initial results are reported.

  18. Water ingestion into jet engine axial compressors

    NASA Technical Reports Server (NTRS)

    Tsuchiya, T.; Murthy, S. N. B.

    1982-01-01

    An axial flow compressor has been tested with water droplet ingestion under a variety of conditions. The results illustrate the manner in which the compressor pressure ratio, efficiency and surging characteristics are affected. A model for estimating the performance of a compressor during water ingestion has been developed and the predictions obtained compare favorably with the test results. It is then shown that with respect to five droplet-associated nonlinearly-interacting processes (namely, droplet-blade interactions, blade performance changes, centrifugal action, heat and mass transfer processes and droplet break-up), the initial water content and centrifugal action play the most dominant roles.

  19. Flow field visualization about external axial corners

    NASA Technical Reports Server (NTRS)

    Talcott, N. A., Jr.

    1978-01-01

    An experimental investigation was conducted to visualize the flow field about external axial corners. The investigation was initiated to provide answers to questions about the inviscid flow pattern for continuing numerical investigations. Symmetrical and asymmetrical corner models were tested at a Reynolds number per meter of 60,700,000. Oil-flow and vapor-screen photographs were taken for both models at angle of attack and yaw. The paper presents the results of the investigation in the form of oil-flow photographs and the surrounding shock wave location obtained from the vapor screens.

  20. Axial tomography from digitized real time radiography

    SciTech Connect

    Zolnay, A.S.; McDonald, W.M.; Doupont, P.A.; McKinney, R.L.; Lee, M.M.

    1985-01-18

    Axial tomography from digitized real time radiographs provides a useful tool for industrial radiography and tomography. The components of this system are: x-ray source, image intensifier, video camera, video line extractor and digitizer, data storage and reconstruction computers. With this system it is possible to view a two dimensional x-ray image in real time at each angle of rotation and select the tomography plane of interest by choosing which video line to digitize. The digitization of a video line requires less than a second making data acquisition relatively short. Further improvements on this system are planned and initial results are reported.

  1. Leveraging Lexical Matching and Ontological Alignment to Map SNOMED CT Surgical Procedures to ICD-10-PCS

    PubMed Central

    Fung, Kin Wah; Xu, Julia; Ameye, Filip; Gutiérrez, Arturo Romero; D'Havé, Arabella

    2016-01-01

    In 2015 ICD-10-PCS replaced ICD-9-CM for coding medical procedures in the U.S. We explored two methods to automatically map SNOMED CT surgical procedures to ICD-10-PCS. First, we used MetaMap to lexically map ICD-10-PCS index terms to SNOMED CT. Second, we made use of the axial structure of ICD-10-PCS and aligned them to defining attributes in SNOMED CT. Lexical mapping produced 45% of correct maps and 44% of broader maps. Ontological mappings were 40% correct and 5% broader. Both correct and broader maps will be useful in assisting mappers to create the map. When the two mapping methods agreed, the accuracy increased to 93%. Reviewing the MetaMap generated body part mappings and using additional information in the SNOMED CT names and definitions can lead to better results for the ontological map. PMID:28269853

  2. Influence of z overscanning on normalized effective doses calculated for pediatric patients undergoing multidetector CT examinations

    SciTech Connect

    Tzedakis, Antonis; Damilakis, John; Perisinakis, Kostas; Karantanas, Apostolos; Karabekios, Spiros; Gourtsoyiannis, Nicholas

    2007-04-15

    The purpose of this study was to evaluate the effect of z overscanning on normalized effective dose for pediatric patients undergoing multidetector-computed tomography (CT) examinations. Five commercially available mathematical anthropomorphic phantoms representing newborn, 1-, 5-, 10-, and 15-year-old patients and the Monte Carlo N-Particle (MCNP, version 4C2) radiation transport code were employed in the current study to simulate pediatric CT exposures. For all phantoms, axial and helical examinations at 120 kV tube voltage were simulated. Scans performed at 80 kV were also simulated. Sex-specific normalized effective doses were estimated for four standard CT examinations i.e., head-neck, chest, abdomen-pelvis, and trunk, for all pediatric phantoms. Data for both axial and helical mode acquisition were obtained. In the helical mode, z overscanning was taken into account. The validity of the Monte Carlo results was verified by comparison with dose data obtained using thermoluminescence dosimetry and a physical pediatric anthropomorphic phantom simulating a 10-year-old child. In all cases normalized effective dose values were found to increase with increasing z overscanning. The percentage differences in normalized data between axial and helical scans may reach 43%, 70%, 36%, and 26% for head-neck, chest, abdomen-pelvis, and trunk studies, respectively. Normalized data for female pediatric patients was in general higher compared to male patients for all ages, examined regions, and z overscanning values. For both male and female children, the normalized effective dose values were reduced as the age was increased. For the same typical exposure conditions, dose values decreased when lower tube voltage was used; for a 1-year-old child, for example, the effective dose was 3.8 times lower when 80 kV instead of 120 kV was used. Normalized data for the estimation of effective dose to pediatric patients undergoing standard axial and helical CT examinations on an

  3. Axial vessel widening in arborescent monocots.

    PubMed

    Petit, Giai; DeClerck, Fabrice A J; Carrer, Marco; Anfodillo, Tommaso

    2014-02-01

    Dicotyledons have evolved a strategy to compensate for the increase in hydraulic resistance to water transport with height growth by widening xylem conduits downwards. In monocots, the accumulation of hydraulic resistance with height should be similar, but the absence of secondary growth represents a strong limitation for the maintenance of xylem hydraulic efficiency during ontogeny. The hydraulic architecture of monocots has been studied but it is unclear how monocots arrange their axial vascular structure during ontogeny to compensate for increases in height. We measured the vessel lumina and estimated the hydraulic diameter (Dh) at different heights along the stem of two arborescent monocots, Bactris gasipaes (Kunth) and Guadua angustifolia (Kunth). For the former, we also estimated the variation in Dh along the leaf rachis. Hydraulic diameter increased basally from the stem apex to the base with a scaling exponent (b) in the range of those reported for dicot trees (b = 0.22 in B. gasipaes; b = 0.31 and 0.23 in G. angustifolia). In B. gasipaes, vessels decrease in Dh from the stem's centre towards the periphery, an opposite pattern compared with dicot trees. Along the leaf rachis, a pattern of increasing Dh basally was also found (b = 0.13). The hydraulic design of the monocots studied revealed an axial pattern of xylem conduits similar to those evolved by dicots to compensate and minimize the negative effect of root-to-leaf length on hydrodynamic resistance to water flow.

  4. Pulsed Detonation Operation of an Axial Turbine

    NASA Astrophysics Data System (ADS)

    Munday, David; St. George, Andrew; Driscoll, Robert; Gutmark, Ephraim; Gas Dynamics and Propulsion Lab Team

    2013-11-01

    A detonation is by its nature a more thermodynamically efficient combustion mode than deflagration. Several attempts are underway to integrate detonating combustion into turbomachines in order to realize the increased efficiency available, save resources and reduce emissions. One approach to this challenge is to employ pulsed detonations as from pulsed detonation engines (PDEs) and use the pulsed outflow to drive a turbine. The difficulty with this approach is that turbines, especially the more efficient axial turbines suffer in efficiency when their inflow is pulsed. At present there is not even a commonly acknowledged turbine efficiency measure which works reasonably for a pulsed input. The present work investigates the efficiency of an axial turbine with pulsed flow. Initial tests are performed with non-combusting flow in order to study the influence of pulsation on the turbine performance. This cold flow will admit a broader range of instrumentation which can be inserted within the turbine. This allows time-resolved measure of the flow angles which have a pronounced effect on the turbine performance. Later tests with detonating inflow yield global measures and these are compared to the non-combusting results. Work sponsored by Innovative Scientific Solutions, Inc.

  5. Microbubbling by co-axial electrohydrodynamic atomization.

    PubMed

    Farook, U; Stride, E; Edirisinghe, M J; Moaleji, R

    2007-08-01

    The preparation of microbubble suspensions is an important feature of medical engineering research. Recently, co-axial electrohydrodynamic atomization was used in our laboratory for the first time to prepare microbubble suspensions. In this paper, using a model glycerol-air system, we investigate in detail the characteristics of this microbubbling process. Modes of microbubbling are elucidated with respect to applied voltage and liquid and air flow rates. Thus, a parametric plot is constructed to identify a liquid and gas flow rate regime, which allows continuous microbubbling. This map provides a basis for the selection of a suitable combination of liquid and gas flow rates particularly in relation to yield and bubble size. The mechanism of microbubbling in microfluidic systems is compared with that of microbubbling by co-axial electrohydrodynamic atomization to identify the advantages and the limiting factors of the latter. Stability of microbubbles prepared by this method in terms of variation of diameter as a function of time is compared with previous literature on the dissolution of microbubbles with an air core and suggests the need for further work to stabilize the bubbles.

  6. CT maxillary sinus evaluation-A retrospective cohort study

    PubMed Central

    Vaz, Paula; Faria-Almeida, Ricardo; Braga, Ana-Cristina; Felino, António

    2015-01-01

    Background Proximity of the dental roots to the sinus floor makes dental disease a probable cause of maxillary sinusitis. The aim of this study was to find out if maxillary sinus pathologic changes were more prevalent in patients with dental disease and to evaluate the performance of computed tomography (CT) in analyzing and detecting apical periodontitis and other odontogenic causes on the maxillary sinusitis etiology in a Portuguese Caucasian population. Material and Methods Retrospective cohort study. The total sample of 504 patients and their CT was included in this study. The patients were from a private dental clinic, specializing in oral surgery, where the first complaint was not directly related to sinus disease, but with dental pathology. For each patient, the etiological factors of maxillary sinusitis and the imaging CT findings were analyzed. All the axial, coronal and sagittal CT slices were evaluated and general data were registered. The latter was selected based on the maxillary sinus CT published literature. Results 32.40% of patients presented normal sinus (without any etiological factor associated), 29.00% showed presence of etiological and imaging findings in the maxillary sinus, 20.60% had only imaging changes in the maxillary sinus and 18.00% of patients presented only etiological factors and no change in the maxillary sinus. Conclusions Radiological imaging is an important tool for establishing the diagnosis of maxillary sinus pathology. These results indicate that the CT scan should be an excellent tool for complement the odontogenic sinusitis diagnosis. Key words: Maxillary sinusitis/etiology, odontogenic, computed tomography, maxillary sinus. PMID:25858084

  7. Quantification with a dedicated breast PET/CT scanner

    PubMed Central

    Bowen, Spencer L.; Ferrero, Andrea; Badawi, Ramsey D.

    2012-01-01

    Purpose: Dedicated breast PET/CT is expected to have utility in local staging, surgical planning, monitoring of therapy response, and detection of residual disease for breast cancer. Quantitative metrics will be integral to several such applications. The authors present a validation of fully 3D data correction schemes for a custom built dedicated breast PET/CT (DbPET/CT) scanner via 18F-FDG phantom scans. Methods: A component-based normalization was implemented, live-time was estimated with a multicomponent model, and a variance reduced randoms estimate was computed from delayed coincidences. Attenuation factors were calculated by using a CT based segmentation scheme while scatter was computed using a Monte Carlo (MC) simulation method. As no performance standard currently exists for breast PET systems, custom performance tests were created based on prior patient imaging results. Count-rate linearity for live-time and randoms corrections was measured with a decay experiment for a solid polyethylene cylinder phantom with an offset line source. A MC simulation was used to validate attenuation correction, a multicompartment phantom with asymmetric activity distribution provided an assessment of scatter correction, and image uniformity after geometric and detector normalization was measured from a high count scan of a uniform cylinder phantom. Raw data were reconstructed with filtered back projection (FBP) after Fourier rebinning. To quantify performance absolute activity concentrations, contrast recovery coefficients and image uniformity were calculated through region of interest analysis. Results: The most significant source of error was attributed to mispositioning of events due to pile-up, presenting in count-related axial and transaxial nonuniformities that were not corrected for with the normalization method used here. Within the range of singles counts observed during clinical trials residual error after applying all corrections was comparable to that of a

  8. Performance evaluation of Biograph PET/CT system based on Monte Carlo simulation

    NASA Astrophysics Data System (ADS)

    Wang, Bing; Gao, Fei; Liu, Hua-Feng

    2010-10-01

    Combined lutetium oxyorthosilicate (LSO) Biograph PET/CT is developed by Siemens Company and has been introduced into medical practice. There is no septa between the scintillator rings, the acquisition mode is full 3D mode. The PET components incorporate three rings of 48 detector blocks which comprises a 13×13 matrix of 4×4×20mm3 elements. The patient aperture is 70cm, the transversal field of view (FOV) is 58.5cm, and the axial field of view is 16.2cm. The CT components adopt 16 slices spiral CT scanner. The physical performance of this PET/CT scanner has been evaluated using Monte Carlo simulation method according to latest NEMA NU 2-2007 standard and the results have been compared with real experiment results. For PET part, in the center FOV the average transversal resolution is 3.67mm, the average axial resolution is 3.94mm, and the 3D-reconstructed scatter fraction is 31.7%. The sensitivities of the PET scanner are 4.21kcps/MBq and 4.26kcps/MBq at 0cm and 10cm off the center of the transversal FOV. The peak NEC is 95.6kcps at a concentration of 39.2kBq/ml. The spatial resolution of CT part is up to 1.12mm at 10mm off the center. The errors between simulated and real results are permitted.

  9. Visualization of an actively bleeding cortical vessel into the subdural space by CT angiography.

    PubMed

    Dalfino, John C; Boulos, Alan S

    2010-10-01

    Spontaneous subdural hematomas of arterial origin are rare with only a few published case reports in the literature. In the CT era, vessel imaging of extra-axial hematomas is not commonly performed. In this case report we present a patient with a large, spontaneous acute subdural hematoma that demonstrated active contrast extravasation from a small cortical vessel on CT angiography. During surgical evacuation the vessel was confirmed to be a small cortical artery that was bulging through the arachnoid membrane and bleeding into the subdural space. The historical, radiographic, and clinical aspects of this unusual cause of subdural hematoma are discussed.

  10. The treatment of refractory atlanto-axial rotatory fixation using a halo vest: results of a case series involving seven children.

    PubMed

    Tauchi, R; Imagama, S; Kanemura, T; Yoshihara, H; Sato, K; Deguchi, M; Kamiya, M; Ishiguro, N

    2011-08-01

    We reviewed seven children with torticollis due to refractory atlanto-axial rotatory fixation who were treated in a halo vest. Pre-operative three-dimensional CT and sagittal CT imaging showed deformity of the superior articular process of C2 in all patients. The mean duration of halo vest treatment was 67 days (46 to 91). The mean follow-up was 34 months (8 to 73); at the latest review six patients demonstrated remodelling of the deformed articular process. The other child, who had a more severe deformity, required C1-2 fusion. We suggest that patients with atlanto-axial rotatory fixation who do not respond to conservative treatment and who have deformity of the superior articular process of C2 should undergo manipulative reduction and halo-vest fixation for two to three months to induce remodelling of the deformed superior articular process before C1-2 fusion is considered.

  11. A technique to determine a desired preparation axial inclination.

    PubMed

    Parker, M Harry; Ivanhoe, John R; Blalock, John S; Frazier, Kevin B; Plummer, Kevin D

    2003-10-01

    The guidelines recommended in the literature for the convergence angle of a crown preparation vary from 3 to 24 degrees. There is a lack of guidelines on techniques to achieve a specific axial inclination. The purpose of this article was to present a practical technique, with a diamond rotary cutting instrument of known axial inclination, to determine the diamond rotary cutting instrument angulations required to achieve the desired axial inclination of a preparation.

  12. Elastic Buckling of Orthotropic Plates Under Varying Axial Stresses

    NASA Technical Reports Server (NTRS)

    Badir, Ashraf; Hu, Hurang; Diallo, Abdouramane

    1997-01-01

    The elastic buckling load of simply supported rectangular orthotropic plates subjected to a second degree parabolic variation of axial stresses in the longitudinal direction is calculated using analytical methods. The variation of axial stresses is equilibrated by nonuniform shear stresses along the plate edges and transverse normal stresses. The influence of the aspect ratio is examined, and the results are compared with plates subjected to uniform axial stresses.

  13. U(1) axial charge in the chiral limit

    NASA Astrophysics Data System (ADS)

    Ji, Xiangdong

    1990-07-01

    The U(1) axial-vector form factor is studied using an unsubtracted dispersion relation. The associated axial charge is shown to be analytic in quark masses in the chiral limit although individual terms in the Cheng-Li separation exhibit large isospin and flavor-SU(3) symmetry breaking. A new separation of the U(1) axial charge is proposed, based on the wave functions of the physical states entering in the spectral density.

  14. 4D-Imaging of the Lung: Reproducibility of Lesion Size and Displacement on Helical CT, MRI, and Cone Beam CT in a Ventilated Ex Vivo System

    SciTech Connect

    Biederer, Juergen Dinkel, Julien; Remmert, Gregor; Jetter, Siri; Nill, Simeon; Moser, Torsten; Bendl, Rolf; Thierfelder, Carsten; Fabel, Michael; Oelfke, Uwe; Bock, Michael; Plathow, Christian; Bolte, Hendrik; Welzel, Thomas; Hoffmann, Beata; Hartmann, Guenter; Schlegel, Wolfgang; Debus, Juergen; Heller, Martin

    2009-03-01

    Purpose: Four-dimensional (4D) imaging is a key to motion-adapted radiotherapy of lung tumors. We evaluated in a ventilated ex vivo system how size and displacement of artificial pulmonary nodules are reproduced with helical 4D-CT, 4D-MRI, and linac-integrated cone beam CT (CBCT). Methods and Materials: Four porcine lungs with 18 agarose nodules (mean diameters 1.3-1.9 cm), were ventilated inside a chest phantom at 8/min and subject to 4D-CT (collimation 24 x 1.2 mm, pitch 0.1, slice/increment 24x10{sup 2}/1.5/0.8 mm, pitch 0.1, temporal resolution 0.5 s), 4D-MRI (echo-shared dynamic three-dimensional-flash; repetition/echo time 2.13/0.72 ms, voxel size 2.7 x 2.7 x 4.0 mm, temporal resolution 1.4 s) and linac-integrated 4D-CBCT (720 projections, 3-min rotation, temporal resolution {approx}1 s). Static CT without respiration served as control. Three observers recorded lesion size (RECIST-diameters x/y/z) and axial displacement. Interobserver- and interphase-variation coefficients (IO/IP VC) of measurements indicated reproducibility. Results: Mean x/y/z lesion diameters in cm were equal on static and dynamic CT (1.88/1.87; 1.30/1.39; 1.71/1.73; p > 0.05), but appeared larger on MRI and CBCT (2.06/1.95 [p < 0.05 vs. CT]; 1.47/1.28 [MRI vs. CT/CBCT p < 0.05]; 1.86/1.83 [CT vs. CBCT p < 0.05]). Interobserver-VC for lesion sizes were 2.54-4.47% (CT), 2.29-4.48% (4D-CT); 5.44-6.22% (MRI) and 4.86-6.97% (CBCT). Interphase-VC for lesion sizes ranged from 2.28% (4D-CT) to 10.0% (CBCT). Mean displacement in cm decreased from static CT (1.65) to 4D-CT (1.40), CBCT (1.23) and MRI (1.16). Conclusions: Lesion sizes are exactly reproduced with 4D-CT but overestimated on 4D-MRI and CBCT with a larger variability due to limited temporal and spatial resolution. All 4D-modalities underestimate lesion displacement.

  15. Nuclear axial currents in chiral effective field theory

    DOE PAGES

    Baroni, Alessandro; Girlanda, Luca; Pastore, Saori; ...

    2016-01-11

    Two-nucleon axial charge and current operators are derived in chiral effective field theory up to one loop. The derivation is based on time-ordered perturbation theory and accounts for cancellations between the contributions of irreducible diagrams and the contributions owing to nonstatic corrections from energy denominators of reducible diagrams. Ultraviolet divergencies associated with the loop corrections are isolated in dimensional regularization. The resulting axial current is finite and conserved in the chiral limit, while the axial charge requires renormalization. As a result, a complete set of contact terms for the axial charge up to the relevant order in the power countingmore » is constructed.« less

  16. Nuclear axial currents in chiral effective field theory

    SciTech Connect

    Baroni, Alessandro; Girlanda, Luca; Pastore, Saori; Schiavilla, Rocco; Viviani, Michele

    2016-01-11

    Two-nucleon axial charge and current operators are derived in chiral effective field theory up to one loop. The derivation is based on time-ordered perturbation theory and accounts for cancellations between the contributions of irreducible diagrams and the contributions owing to nonstatic corrections from energy denominators of reducible diagrams. Ultraviolet divergencies associated with the loop corrections are isolated in dimensional regularization. The resulting axial current is finite and conserved in the chiral limit, while the axial charge requires renormalization. As a result, a complete set of contact terms for the axial charge up to the relevant order in the power counting is constructed.

  17. Motion and emotion: anxiety-axial connections in Parkinson's disease.

    PubMed

    Šumec, Rastislav; Rektorová, Irena; Jech, Robert; Menšíková, Kateřina; Roth, Jan; Růžička, Evžen; Sochorová, Dana; Dušek, Ladislav; Kaňovský, Petr; Rektor, Ivan; Pavlík, Tomáš; Filip, Pavel; Bareš, Martin

    2017-03-01

    Anxiety is a serious and frequent complication in Parkinson's disease (PD) that significantly affects the quality of life of patients. Multiple neuroanatomical, experimental, and clinical studies suggest its close association with axial disturbances. However, whether this relation applies for PD patients (commonly suffering from axial difficulties, such as balance and gait disturbance) has not been properly tested yet. The purpose of this study was to determine whether PD patients suffering from axial symptoms have higher levels of anxiety than others and to identify other factors associated with anxiety-axial connections. In this questionnaire study, 212 patients with PD were assessed by standardized scales, such as Hamilton Anxiety Scale, Montgomery-Asberg Depression Rating Scale, Montreal Cognitive Assessment, examining their mood and cognitive status. These data were correlated to dominant motor symptoms of these patients, such as tremor, rigidity, bradykinesia, and axial symptoms. Unlike other motor symptoms, only axial symptoms showed to be significantly related to higher levels of anxiety. The patients suffering from anxiety and axial problems have also shown significantly higher depression levels. Axial disturbances are related to higher anxiety levels in PD patients. It is crucial to pay high attention to symptoms of anxiety in patients having postural instability or gait disorder. Further clinical studies are desirable to investigate new, practical implications of anxiety-axial connection to provide complex management options of these serious symptoms.

  18. Modular functional organisation of the axial locomotor system in salamanders.

    PubMed

    Cabelguen, Jean-Marie; Charrier, Vanessa; Mathou, Alexia

    2014-02-01

    Most investigations on tetrapod locomotion have been concerned with limb movements. However, there is compelling evidence that the axial musculoskeletal system contributes to important functions during locomotion. Adult salamanders offer a remarkable opportunity to examine these functions because these amphibians use axial undulations to propel themselves in both aquatic and terrestrial environments. In this article, we review the currently available biological data on axial functions during various locomotor modes in salamanders. We also present data showing the modular organisation of the neural networks that generate axial synergies during locomotion. The functional implication of this modular organisation is discussed.

  19. Axial flux machine, stator and fabrication method

    DOEpatents

    Carl, Ralph James

    2004-03-16

    An axial flux machine comprises: a soft magnetic composite stator extension positioned in parallel with a rotor disk and having slots; soft magnetic composite pole pieces attached to the stator extension and facing a permanent magnet on the rotor disk, each comprising a protrusion situated within a respective one of the slots, each protrusion shaped so as to facilitate orientation of the respective pole piece with respect to the stator extension; electrical coils, each wrapped around a respective one of the pole pieces. In another embodiment the soft magnetic composite pole pieces each comprise a base portion around with the electrical coils are wound and a trapezoidal shield portion a plurality of heights with a first height in a first region being longer than a second height in a second region, the second region being closer to a pole-to-pole gap than the first region.

  20. Hierarchical tapered bar elements undergoing axial deformation

    NASA Technical Reports Server (NTRS)

    Ganesan, N.; Thampi, S. K.

    1992-01-01

    A method is described to model the dynamics of tapered axial bars of various cross sections based on the well-known Craig/Bampton component mode synthesis technique. This element is formed in terms of the static constraint modes and interface restrained normal modes. This is in contrast with the finite elements as implemented in NASTRAN where the interface restrained normal modes are neglected. These normal modes are in terms of Bessel functions. Restoration of a few of these modes leads to higher accuracy with fewer generalized coordinates. The proposed models are hierarchical so that all lower order element matrices are embedded in higher order element matrices. The advantages of this formulation compared to standard NASTRAN truss element formulation are demonstrated through simple numerical examples.

  1. Axially symmetric static sources of gravitational field

    NASA Astrophysics Data System (ADS)

    Hernandez-Pastora, J. L.; Herrera, L.; Martin, J.

    2016-12-01

    A general procedure to find static and axially symmetric, interior solutions to the Einstein equations is presented. All the so obtained solutions, verify the energy conditions for a wide range of values of the parameters, and match smoothly to some exterior solution of the Weyl family, thereby representing globally regular models describing non-spherical sources of gravitational field. In the spherically symmetric limit, all our models converge to the well known incompressible perfect fluid solution. The key stone of our approach is based on an ansatz allowing to define the interior metric in terms of the exterior metric functions evaluated at the boundary source. Some particular sources are obtained, and the physical variables of the energy-momentum tensor are calculated explicitly, as well as the geometry of the source in terms of the relativistic multipole moments. The total mass of different configurations is also calculated, it is shown to be equal to the monopole of the exterior solution.

  2. Axially symmetric shapes with minimum wave drag

    NASA Technical Reports Server (NTRS)

    Heaslet, Max A; Fuller, Franklyn B

    1956-01-01

    The external wave drag of bodies of revolution moving at supersonic speeds can be expressed either in terms of the geometry of the body, or in terms of the body-simulating axial source distribution. For purposes of deriving optimum bodies under various given conditions, it is found that the second of the methods mentioned is the more tractable. By use of a quasi-cylindrical theory, that is, the boundary conditions are applied on the surface of a cylinder rather than on the body itself, the variational problems of the optimum bodies having prescribed volume or caliber are solved. The streamline variations of cross-sectional area and drags of the bodies are exhibited, and some numerical results are given.

  3. Aerodynamics of advanced axial-flow turbomachinery

    NASA Technical Reports Server (NTRS)

    Serovy, G. K.; Kavanagh, P.; Kiishi, T. H.

    1980-01-01

    A multi-task research program on aerodynamic problems in advanced axial-flow turbomachine configurations was carried out at Iowa State University. The elements of this program were intended to contribute directly to the improvement of compressor, fan, and turbine design methods. Experimental efforts in intra-passage flow pattern measurements, unsteady blade row interaction, and control of secondary flow are included, along with computational work on inviscid-viscous interaction blade passage flow techniques. This final report summarizes the results of this program and indicates directions which might be taken in following up these results in future work. In a separate task a study was made of existing turbomachinery research programs and facilities in universities located in the United States. Some potentially significant research topics are discussed which might be successfully attacked in the university atmosphere.

  4. Buckling of cylindrical panels under axial compression

    NASA Technical Reports Server (NTRS)

    Sobel, L. H.; Weller, T.; Agarwal, B. L.

    1976-01-01

    This paper investigates the effects of boundary conditions and panel width on the axially compressive buckling behavior of unstiffened, isotropic, circular cylindrical panels. Numerical results are presented for eight different sets of boundary conditions along the straight edges of the panels. For all sets of boundary conditions except one (SS1), the results show that the panel buckling loads monotonically approach the complete cylinder buckling load from above as the panel width is increased. Low buckling loads, sometimes less than half the complete cylinder buckling load, are found for simply supported panels with free in-plane edge displacements (SS1). It is observed that the prevention of circumferential edge displacement is the most important in-plane boundary condition from the point of view of increasing the buckling load; and that the prevention of edge rotation in the circumferential direction also significantly increases the buckling load.

  5. Dose conversion coefficients for CT examinations of adults with automatic tube current modulation

    NASA Astrophysics Data System (ADS)

    Schlattl, H.; Zankl, M.; Becker, J.; Hoeschen, C.

    2010-10-01

    Automatic tube current modulation (TCM) is used in modern CT devices. This is implemented in the numerical calculation of dose conversion coefficients for CT examinations. For four models of adults, the female and male reference models of ICRP and ICRU and a lighter and a heavier female model, dose conversion coefficients normalized to CTDIvol (DCCCT) have been computed with a Monte Carlo transport code for CT scans with and without TCM. It could be shown for both cases that reliable values for spiral CT scans are obtained when combining the results from an appropriate set of axial scans. The largest organ DCCCT are presented for typical CT examinations for all four models. The impact of TCM is greatest for chest, pelvis and whole-trunk CT examinations, where with TCM the effective DCCCT can be 20-25% lower than without TCM. Typical organs with strong dependence on TCM are thyroid, urinary bladder, lungs and oesophagus. While the DCCCT of thyroid and urinary bladder are mainly sensitive to angular TCM, the DCCCT of lungs and oesophagus are influenced primarily by longitudinal TCM. The impact of the body stature on the effective DCCCT is of the same order as the effect of TCM. Thus, for CT scans in the trunk region, accurate dose values can only be obtained when different sets of DCCCT are employed that are appropriate for the patient's sex and stature and the actual TCM settings.

  6. Assessment of bilateral filter on 1/2-dose chest-pelvis CT views.

    PubMed

    Al-Hinnawi, Abdel Razzak; Daear, Mohammed; Huwaijah, Said

    2013-07-01

    A bilateral filter (BF) is a non-linear filter that has been proved to de-noise images without overrunning edges. Multi-slice computerized tomography (CT) may employ a BF to participate in dose reduction. This paper quantifies the role of the BF in achieving this objective on 1/2-dose CT. Two sets of CT images are acquired for the chest-pelvis at two different radiation doses. The BF was applied on the 1/2-dose CT images by use of various window sizes. Each time, a set of values of the BF range was fixed while the BF domain was modified. The goal was to observe the behavior of the BF on 1/2-dose CT images in comparison with full-dose CT images. The comparison was carried out by use of four co-occurrence matrix descriptors. Additionally, the peak signal-to-noise ratio (PSNR) and the mean square error (MSE) were reported. The study was applied to the sagittal, coronal, and axial CT views. The results showed that the impact of applying a BF varies among different CT views. The BF can retrieve only part of the signal being lost due to reduction of the radiation dose by one half. Yet, the BF improves the appearance of the 1/2-dose chest-pelvis CT examination. Thus, the BF can contribute to a 50% dose reduction. A procedure for employing the BF on CT machines is proposed. The results also showed that texture descriptors are similar to the PSNR and MSE in providing quantities for assessing medical image quality.

  7. Quantification of AC electromagnetic tracking system accuracy in a CT scanner environment

    NASA Astrophysics Data System (ADS)

    Shen, Eric; Shechter, Guy; Kruecker, Jochen; Stanton, Douglas

    2007-03-01

    The purpose of this study was to quantify the effects of a computed tomography (CT) scanner environment on the positional accuracy of an AC electromagnetic tracking system, the second generation NDI Aurora. A three-axis positioning robot was used to move an electromagnetically tracked needle above the CT table throughout a 30cm by 30cm axial plane sampled in 2.5cm steps. The corresponding position data was captured from the Aurora and was registered to the positioning system data using a rigid body transformation minimizing the least squares L2-norm. Data was sampled at varying distances from the CT gantry (three feet, two feet, and one foot) and with the CT table in a nominal position and lowered by 10cm. A coordinate system was defined with the x axis normal to the CT table and the origin at the center of the CT table, and the z axis spanning the table in the lateral direction with the origin at the center of the CT table. In this coordinate system, the positional relationships of each sampled point, the CT table, and the Aurora field generator are clearly defined. This allows error maps to be displayed in accurate spatial relationship to the CT scanner as well as to a representative patient anatomy. By quantifying the distortions in relation to the position of CT scanner components and the Aurora field generator, the optimal working field of view and recommended guidelines for operation can be determined such that targeting inside human anatomy can be done with reasonable expectations of desired performance.

  8. New approach to a novel axially chiral ligand showing spontaneous enrichment of axial chirality.

    PubMed

    Hasegawa, Tomokuni; Omote, Masaaki; Sato, Kazuyuki; Ando, Akira; Kumadaki, Itsumaro

    2003-03-01

    We have synthesized novel axially chiral ligand with two chiral centers, (R)-(R)(2)- and (S)-(S)(2)-2,2'-bis(2,2,2-trifluoro-1-hydroxyethyl)biphenyl (1), which showed a high asymmetric induction when used as ligand. Here, another new approach to 1 by kinetic and thermodynamic resolution is presented which gave these ligands in a much shorter steps, in a higher yield, and in a higher enantiomeric excess.

  9. Chronic osteomyelitis examined by CT

    SciTech Connect

    Wing, V.W.; Jeffrey, R.B. Jr.; Federle, M.P.; Helms, C.A.; Trafton, P.

    1985-01-01

    CT examination of 25 patients who had acute exacerbations of chronic osteomyelitis allowed for the correct identification of single or multiple sequestra in 14 surgical patients. Plain radiographs were equivocal for sequestra in seven of these patients, because the sequestra were too small or because diffuse bony sclerosis was present. CT also demonstrated a foreign body and five soft tissue abscesses not suspected on the basis of plain radiographs. CT studies, which helped guide the operative approach, were also useful in treating those patients whose plain radiographs were positive for sequestra. The authors review the potential role of CT in evaluating patients with chronic osteomyelitis.

  10. An Axial-Torsional, Thermomechanical Fatigue Testing Technique

    NASA Technical Reports Server (NTRS)

    Kalluri, Sreeramesh; Bonacuse, Peter J.

    1995-01-01

    A technique for conducting strain-controlled, thermomechanical, axial-torsional fatigue tests on thin-walled tubular specimens was developed. Three waveforms of loading, namely, the axial strain waveform, the engineering shear strain waveform, and the temperature waveform were required in these tests. The phasing relationships between the mechanical strain waveforms and the temperature and axial strain waveforms were used to define a set of four axial-torsional, thermomechanical fatigue (AT-TMF) tests. Real-time test control (3 channels) and data acquisition (a minimum of 7 channels) were performed with a software program written in C language and executed on a personal computer. The AT-TMF testing technique was used to investigate the axial-torsional thermomechanical fatigue behavior of a cobalt-base superalloy, Haynes 188. The maximum and minimum temperatures selected for the AT-TMF tests were 760 and 316 C, respectively. Details of the testing system, calibration of the dynamic temperature profile of the thin-walled tubular specimen, thermal strain compensation technique, and test control and data acquisition schemes, are reported. The isothermal, axial, torsional, and in- and out-of-phase axial-torsional fatigue behaviors of Haynes 188 at 316 and 760 C were characterized in previous investigations. The cyclic deformation and fatigue behaviors of Haynes 188 in AT-TMF tests are compared to the previously reported isothermal axial-torsional behavior of this superalloy at the maximum and minimum temperatures.

  11. An Unbroken Axial-Vector Current Conservation Law

    NASA Astrophysics Data System (ADS)

    Sharafiddinov, Rasulkhozha S.

    2016-04-01

    The mass, energy and momentum of the neutrino of a true flavor have an axial-vector nature. As a consequence, the left-handed truly neutral neutrino in an axial-vector field of emission can be converted into a right-handed one and vice versa. This predicts the unidenticality of masses, energies and momenta of neutrinos of the different components. Recognizing such a difference in masses, energies, momenta and accepting that the left-handed axial-vector neutrino and the right-handed antineutrino of true neutrality refer to long-lived C-odd leptons, and the right-handed truly neutral neutrino and the left-handed axial-vector antineutrino are of short-lived fermions of C-oddity, we would write a new CP-even Dirac equation taking into account the flavor symmetrical axial-vector mass, energy and momentum matrices. Their presence explains the spontaneous mirror symmetry violation, confirming that an axial-vector current conservation law has never violated. They reflect the availability of a mirror Minkowski space in which a neutrino is characterized by left as well as by right space-time coordinates. Therefore, it is not surprising that whatever the main purposes experiments about a quasielastic axial-vector mass say in favor of an axial-vector mirror Minkowski space-time.

  12. An Unbroken Axial-Vector Current Conservation Law

    NASA Astrophysics Data System (ADS)

    Sharafiddinov, Rasulkhozha S.

    2016-03-01

    The mass, energy and momentum of the neutrino of a true flavor have an axial-vector nature. As a consequence, the left-handed truly neutral neutrino in an axial-vector field of emission can be converted into a right-handed one and vice versa. This predicts the unidenticality of masses, energies and momenta of neutrinos of the different components. Recognizing such a difference in masses, energies, momenta and accepting that the left-handed axial-vector neutrino and the right-handed antineutrino of true neutrality refer to long-lived C-odd leptons, and the right-handed truly neutral neutrino and the left-handed axial-vector antineutrino are of short-lived fermions of C-oddity, we would write a new CP-even Dirac equation taking into account the flavor symmetrical axial-vector mass, energy and momentum matrices. Their presence explains the spontaneous mirror symmetry violation, confirming that an axial-vector current conservation law has never violated. They reflect the availability of a mirror Minkowski space in which a neutrino is characterized by left as well as by right space-time coordinates. Therefore, it is not surprising that whatever the main purposes experiments about a quasielastic axial-vector mass say in favor of an axial-vector mirror Minkowski space-time.

  13. Study of a new airfoil used in reversible axial fans

    NASA Technical Reports Server (NTRS)

    Li, Chaojun; Wei, Baosuo; Gu, Chuangang

    1991-01-01

    The characteristics of the reverse ventilation of axial flow are analyzed. An s shaped airfoil with a double circular arc was tested in a wind tunnel. The experimental results showed that the characteristics of this new airfoil in reverse ventilation are the same as those in normal ventilation, and that this airfoil is better than the existing airfoils used on reversible axial fans.

  14. Axial resolution of a chromatic dispersion confocal microscopy

    NASA Astrophysics Data System (ADS)

    Garzon Reyes, Johnson; Meneses, J.; Plata, Arturo; Tribillon, Gilbert M.; Gharbi, Tijani

    2004-10-01

    An analysis of the axial resolution of a chromatic dispersion confocal microscopy is presented. The system is based on the principle of focus multiplexing by wavelength encoding due to a phase Fresnel lens. The axial resolution is related with the measure of the FWHM value of every spectral response.

  15. A new approach to radial and axial gauges

    NASA Astrophysics Data System (ADS)

    Weigert, Heribert; Heinz, Ulrich

    1992-03-01

    We develop a new path integral formulation of QCD in radial and axial gauges. This formalism yields free propagators which are free of gauge poles. We find that radial gauges are ghost free. In axial gauges ghosts cannot generally be excluded from the formalism due to the need to fix the residual gauge freedom.

  16. Dedicated Cone-Beam CT System for Extremity Imaging

    PubMed Central

    Al Muhit, Abdullah; Zbijewski, Wojciech; Thawait, Gaurav K.; Stayman, J. Webster; Packard, Nathan; Senn, Robert; Yang, Dong; Foos, David H.; Yorkston, John; Siewerdsen, Jeffrey H.

    2014-01-01

    Purpose To provide initial assessment of image quality and dose for a cone-beam computed tomographic (CT) scanner dedicated to extremity imaging. Materials and Methods A prototype cone-beam CT scanner has been developed for imaging the extremities, including the weight-bearing lower extremities. Initial technical assessment included evaluation of radiation dose measured as a function of kilovolt peak and tube output (in milliampere seconds), contrast resolution assessed in terms of the signal difference–to-noise ratio (SDNR), spatial resolution semiquantitatively assessed by using a line-pair module from a phantom, and qualitative evaluation of cadaver images for potential diagnostic value and image artifacts by an expert CT observer (musculoskeletal radiologist). Results The dose for a nominal scan protocol (80 kVp, 108 mAs) was 9 mGy (absolute dose measured at the center of a CT dose index phantom). SDNR was maximized with the 80-kVp scan technique, and contrast resolution was sufficient for visualization of muscle, fat, ligaments and/or tendons, cartilage joint space, and bone. Spatial resolution in the axial plane exceeded 15 line pairs per centimeter. Streaks associated with x-ray scatter (in thicker regions of the patient—eg, the knee), beam hardening (about cortical bone—eg, the femoral shaft), and cone-beam artifacts (at joint space surfaces oriented along the scanning plane—eg, the interphalangeal joints) presented a slight impediment to visualization. Cadaver images (elbow, hand, knee, and foot) demonstrated excellent visibility of bone detail and good soft-tissue visibility suitable to a broad spectrum of musculoskeletal indications. Conclusion A dedicated extremity cone-beam CT scanner capable of imaging upper and lower extremities (including weight-bearing examinations) provides sufficient image quality and favorable dose characteristics to warrant further evaluation for clinical use. © RSNA, 2013 Online supplemental material is available for

  17. Engineering axially vascularized bone in the sheep arteriovenous-loop model.

    PubMed

    Boos, Anja M; Loew, Johanna S; Weigand, Annika; Deschler, Gloria; Klumpp, Dorothee; Arkudas, Andreas; Bleiziffer, Oliver; Gulle, Heinz; Kneser, Ulrich; Horch, Raymund E; Beier, Justus P

    2013-08-01

    Treatment of complex bone defects in which vascular supply is insufficient is still a challenge. To overcome the limitations from autologous grafts, a sheep model has been established recently, which is characterized by the development of an independent axial vascularization of a bioartificial construct, permitting microsurgical transplantation. To engineer independently axially vascularized bone tissue in the sheep arteriovenous (AV)-loop model, mesenchymal stem cells (MSCs), without and in combination with recombinant human bone morphogenetic protein-2 (rhBMP-2), were harvested and directly autotransplanted in combination with β-tricalcium phosphate-hydroxyapatite (β-TCP-HA) granules into sheep in this study. After explantation after 12 weeks, histological and immunohistochemical evaluation revealed newly formed bone in both groups. An increased amount of bone area was obtained using directly autotransplanted MSCs with rhBMP-2 stimulation. Osteoblastic and osteoclastic cells were detected adjacent to the newly formed bone, revealing an active bone remodelling process. Directly autotransplanted MSCs can be found close to the β-TCP-HA granules and are contributing to bone formation. Over time, magnetic resonance imaging (MRI) and micro-computed tomography (μCT) imaging confirmed the dense vascularization arising from the AV-loop. This study shows de novo engineering of independently axially vascularized transplantable bone tissue in clinically significant amounts, using directly autotransplanted MSCs and rhBMP-2 stimulation in about 12 weeks in the sheep AV-loop model. This strategy of engineering vascularized transplantable bone tissue could be possibly transferred to the clinic in the future in order to augment current reconstructive strategies.

  18. Development of 1-year-old computational phantom and calculation of organ doses during CT scans using Monte Carlo simulation

    NASA Astrophysics Data System (ADS)

    Pan, Yuxi; Qiu, Rui; Gao, Linfeng; Ge, Chaoyong; Zheng, Junzheng; Xie, Wenzhang; Li, Junli

    2014-09-01

    With the rapidly growing number of CT examinations, the consequential radiation risk has aroused more and more attention. The average dose in each organ during CT scans can only be obtained by using Monte Carlo simulation with computational phantoms. Since children tend to have higher radiation sensitivity than adults, the radiation dose of pediatric CT examinations requires special attention and needs to be assessed accurately. So far, studies on organ doses from CT exposures for pediatric patients are still limited. In this work, a 1-year-old computational phantom was constructed. The body contour was obtained from the CT images of a 1-year-old physical phantom and the internal organs were deformed from an existing Chinese reference adult phantom. To ensure the organ locations in the 1-year-old computational phantom were consistent with those of the physical phantom, the organ locations in 1-year-old computational phantom were manually adjusted one by one, and the organ masses were adjusted to the corresponding Chinese reference values. Moreover, a CT scanner model was developed using the Monte Carlo technique and the 1-year-old computational phantom was applied to estimate organ doses derived from simulated CT exposures. As a result, a database including doses to 36 organs and tissues from 47 single axial scans was built. It has been verified by calculation that doses of axial scans are close to those of helical scans; therefore, this database could be applied to helical scans as well. Organ doses were calculated using the database and compared with those obtained from the measurements made in the physical phantom for helical scans. The differences between simulation and measurement were less than 25% for all organs. The result shows that the 1-year-old phantom developed in this work can be used to calculate organ doses in CT exposures, and the dose database provides a method for the estimation of 1-year-old patient doses in a variety of CT examinations.

  19. Development of 1-year-old computational phantom and calculation of organ doses during CT scans using Monte Carlo simulation.

    PubMed

    Pan, Yuxi; Qiu, Rui; Gao, Linfeng; Ge, Chaoyong; Zheng, Junzheng; Xie, Wenzhang; Li, Junli

    2014-09-21

    With the rapidly growing number of CT examinations, the consequential radiation risk has aroused more and more attention. The average dose in each organ during CT scans can only be obtained by using Monte Carlo simulation with computational phantoms. Since children tend to have higher radiation sensitivity than adults, the radiation dose of pediatric CT examinations requires special attention and needs to be assessed accurately. So far, studies on organ doses from CT exposures for pediatric patients are still limited. In this work, a 1-year-old computational phantom was constructed. The body contour was obtained from the CT images of a 1-year-old physical phantom and the internal organs were deformed from an existing Chinese reference adult phantom. To ensure the organ locations in the 1-year-old computational phantom were consistent with those of the physical phantom, the organ locations in 1-year-old computational phantom were manually adjusted one by one, and the organ masses were adjusted to the corresponding Chinese reference values. Moreover, a CT scanner model was developed using the Monte Carlo technique and the 1-year-old computational phantom was applied to estimate organ doses derived from simulated CT exposures. As a result, a database including doses to 36 organs and tissues from 47 single axial scans was built. It has been verified by calculation that doses of axial scans are close to those of helical scans; therefore, this database could be applied to helical scans as well. Organ doses were calculated using the database and compared with those obtained from the measurements made in the physical phantom for helical scans. The differences between simulation and measurement were less than 25% for all organs. The result shows that the 1-year-old phantom developed in this work can be used to calculate organ doses in CT exposures, and the dose database provides a method for the estimation of 1-year-old patient doses in a variety of CT examinations.

  20. Investigation on viewing direction dependent detectability in a reconstructed 3D volume for a cone beam CT system

    NASA Astrophysics Data System (ADS)

    Park, Junhan; Lee, Changwoo; Baek, Jongduk

    2015-03-01

    In medical imaging systems, several factors (e.g., reconstruction algorithm, noise structures, target size, contrast, etc) affect the detection performance and need to be considered for object detection. In a cone beam CT system, FDK reconstruction produces different noise structures in axial and coronal slices, and thus we analyzed directional dependent detectability of objects using detection SNR of Channelized Hotelling observer. To calculate the detection SNR, difference-of-Gaussian channel model with 10 channels was implemented, and 20 sphere objects with different radius (i.e., 0.25 (mm) to 5 (mm) equally spaced by 0.25 (mm)), reconstructed by FDK algorithm, were used as object templates. Covariance matrix in axial and coronal direction was estimated from 3000 reconstructed noise volumes, and then the SNR ratio between axial and coronal direction was calculated. Corresponding 2D noise power spectrum was also calculated. The results show that as the object size increases, the SNR ratio decreases, especially lower than 1 when the object size is larger than 2.5 mm radius. The reason is because the axial (coronal) noise power is higher in high (low) frequency band, and therefore the detectability of a small (large) object is higher in coronal (axial) images. Our results indicate that it is more beneficial to use coronal slices in order to improve the detectability of a small object in a cone beam CT system.

  1. High Power Co-Axial SRF Coupler

    SciTech Connect

    M.L. Neubauer, R.A. Rimmer

    2009-05-01

    There are over 35 coupler designs for SRF cavities ranging in frequency from 325 to 1500 MHz. Two-thirds of these designs are coaxial couplers using disk or cylindrical ceramics in various combinations and configurations. While it is well known that dielectric losses go down by several orders of magnitude at cryogenic temperatures, it not well known that the thermal conductivity also goes down, and it is the ratio of thermal conductivity to loss tangent (SRF ceramic Quality Factor) and ceramic volume which will determine the heat load of any given design. We describe a novel robust co-axial SRF coupler design which uses compressed window technology. This technology will allow the use of highly thermally conductive materials for cryogenic windows. The mechanical designs will fit into standard-sized ConFlat® flanges for ease of assembly. Two windows will be used in a coaxial line. The distance between the windows is adjusted to cancel their reflections so that the same window can be used in many different applications at various frequencies.

  2. Recent advances in transonic axial compressor aerodynamics

    NASA Astrophysics Data System (ADS)

    Biollo, Roberto; Benini, Ernesto

    2013-01-01

    Transonic axial flow compressors are fundamental components in aircraft engines as they make it possible to maximize pressure ratios per stage unit. This is achieved through a careful combination of both tangential flow deflections and, above all, by taking advantage of shock wave formation around the rotor blades. The resulting flow field is really complex as it features highly three-dimensional inviscid/viscous structures, strong shock-boundary layer interaction and intense tip clearance effects which negatively influence compressor efficiency. Complications are augmented at part load operation, where stall-related phenomena occur. Therefore, considerable research efforts are being spent, both numerically and experimentally, to improve efficiency and stall margin at peak efficiency and near stall operation. The present work aims at giving a complete review of the most recent advances in the field of aerodynamic design and operation of such machines. A great emphasis has been given to highlight the most relevant contribution in this field and to suggest the prospects for future developments.

  3. Small axial compressor technology, volume 1

    NASA Technical Reports Server (NTRS)

    Holman, F. F.; Kidwell, J. R.; Ware, T. C.

    1976-01-01

    A scaled single-stage, highly-loaded, axial-flow transonic compressor was tested at speeds from 70 to 110% design equivalent speed to evaluate the effects of scaling compromises and the individual and combined effects of rotor tip running clearance and rotor shroud casing treatment on the overall and blade element performance. At design speed and 1% tip clearance the stage demonstrated an efficiency of 83.2% at 96.4% design flow and a pressure ratio of 1.865. Casing treatment increased design speed surge margin 2.0 points to 12.8%. Overall performance was essentially unchanged. An increase in rotor running clearance to 2.2%, with smooth casing, reduced design speed peak efficiency 5.7 points, flow by 7.4%, pressure ratio to 1.740, and surge margin to 5.4%. Reinstalling casing treatment regained 3.5 points in design speed peak efficiency, 4.7% flow, increased pressure ratio to 1.800 and surge margin to 8.7%.

  4. Giant cell tumors of the axial skeleton.

    PubMed

    Balke, Maurice; Henrichs, Marcel P; Gosheger, Georg; Ahrens, Helmut; Streitbuerger, Arne; Koehler, Michael; Bullmann, Viola; Hardes, Jendrik

    2012-01-01

    Background. We report on 19 cases of giant cell tumor of bone (GCT) affecting the spine or sacrum and evaluate the outcome of different treatment modalities. Methods. Nineteen patients with GCT of the spine (n = 6) or sacrum (n = 13) have been included in this study. The mean followup was 51.6 months. Ten sacral GCT were treated by intralesional procedures of which 4 also received embolization, and 3 with irradiation only. All spinal GCT were surgically treated. Results. Two (15.4%) patients with sacral and 4 (66.7%) with spinal tumors had a local recurrence, two of the letter developed pulmonary metastases. One local recurrence of the spine was successfully treated by serial arterial embolization, a procedure previously described only for sacral tumors. At last followup, 9 patients had no evidence of disease, 8 had stable disease, 1 had progressive disease, 1 died due to disease. Six patients had neurological deficits. Conclusions. GCT of the axial skeleton have a high local recurrence rate. Neurological deficits are common. En-bloc spondylectomy combined with embolization is the treatment of choice. In case of inoperability, serial arterial embolization seems to be an alternative not only for sacral but also for spinal tumors.

  5. Giant Cell Tumors of the Axial Skeleton

    PubMed Central

    Balke, Maurice; Henrichs, Marcel P.; Gosheger, Georg; Ahrens, Helmut; Streitbuerger, Arne; Koehler, Michael; Bullmann, Viola; Hardes, Jendrik

    2012-01-01

    Background. We report on 19 cases of giant cell tumor of bone (GCT) affecting the spine or sacrum and evaluate the outcome of different treatment modalities. Methods. Nineteen patients with GCT of the spine (n = 6) or sacrum (n = 13) have been included in this study. The mean followup was 51.6 months. Ten sacral GCT were treated by intralesional procedures of which 4 also received embolization, and 3 with irradiation only. All spinal GCT were surgically treated. Results. Two (15.4%) patients with sacral and 4 (66.7%) with spinal tumors had a local recurrence, two of the letter developed pulmonary metastases. One local recurrence of the spine was successfully treated by serial arterial embolization, a procedure previously described only for sacral tumors. At last followup, 9 patients had no evidence of disease, 8 had stable disease, 1 had progressive disease, 1 died due to disease. Six patients had neurological deficits. Conclusions. GCT of the axial skeleton have a high local recurrence rate. Neurological deficits are common. En-bloc spondylectomy combined with embolization is the treatment of choice. In case of inoperability, serial arterial embolization seems to be an alternative not only for sacral but also for spinal tumors. PMID:22448122

  6. Vector and Axial Vector Pion Form Factors

    NASA Astrophysics Data System (ADS)

    Vitz, Michael; PEN Collaboration

    2015-04-01

    Radiative pion decay π+ -->e+ νγ (RPD) provides critical input to chiral perturbation theory (χPT). Aside from the uninteresting ``inner bremsstrahlung'' contribution from QED, the RPD rate contains ``structure dependent'' terms given by FV and FA, the vector and axial-vector pion form factors, respectively. The two appear in the decay rate in combinations FV -FA and FV +FA , i.e., in the so-called SD- and SD+ terms, respectively. The latter has been measured to high precision by the PIBETA collaboration. We report on the analysis of new data, measured by the PEN collaboration in runs between 2008 and 2010 at the Paul Scherrer Institute, Switzerland. We particularly focus on the possibility of improvement in the determination of the SD- term. Precise determinations of FV and FA test the validity of the CVC hypothesis, provide numerical input for the l9 +l10 terms in the χPT lagrangian, and constrain potential non-(V - A) terms, such as a possible tensor term FT. NSF grants PHY-0970013, 1307328, and others.

  7. New treatment targets for axial spondyloarthritis.

    PubMed

    Sieper, Joachim

    2016-12-01

    Axial spondyloarthritis (axSpA) patients can be divided into those with structural damage in the SI joint visible on X-rays, termed radiographic axSpA or AS, and those in an earlier phase of the disease, without structural damage in the SI joint, termed non-radiographic axSpA. TNF-blockers have been shown to be highly effective in the treatment of active axSpA. Interestingly, conventional DMARDs and also non-TNF-blocker biologics targeting IL-1, IL-6 and T cells (abatacept) are not effective. Recent interest has focused on the cytokines IL-23 and IL-17 as potential treatment targets in axSpA. An open-label trial with ustekinumab showed a good efficacy in AS patients. Two placebo-controlled phase 3 trials with a mAb blocking IL-17, secukinumab, showed a good reduction in disease activity, similar to that shown for TNF blockers. Probably triggered by inflammation, new bone formation is another hallmark in AS and a potentially important treatment target. However, a previously reported inhibitory effect of NSAID treatment could not be confirmed in a recent NSAID trial.

  8. Nitinol stent design - understanding axial buckling.

    PubMed

    McGrath, D J; O'Brien, B; Bruzzi, M; McHugh, P E

    2014-12-01

    Nitinol׳s superelastic properties permit self-expanding stents to be crimped without plastic deformation, but its nonlinear properties can contribute towards stent buckling. This study investigates the axial buckling of a prototype tracheobronchial nitinol stent design during crimping, with the objective of eliminating buckling from the design. To capture the stent buckling mechanism a computational model of a radial force test is simulated, where small geometric defects are introduced to remove symmetry and allow buckling to occur. With the buckling mechanism ascertained, a sensitivity study is carried out to examine the effect that the transitional plateau region of the nitinol loading curve has on stent stability. Results of this analysis are then used to redesign the stent and remove buckling. It is found that the transitional plateau region can have a significant effect on the stability of a stent during crimping, and by reducing the amount of transitional material within the stent hinges during loading the stability of a nitinol stent can be increased.

  9. Axial residual stresses in boron fibers

    NASA Technical Reports Server (NTRS)

    Behrendt, D. R.

    1978-01-01

    The axial residual stress distribution as a function of radius was determined from the fiber surface to the core including the average residual stress in the core. Such measurements on boron on tungsten (B/W) fibers show that the residual stresses for 102, 142, 203, and 366 micron diameter fibers were similar, being compressive at the surface and changing monotonically to a region of tensile within the boron. At approximately 25 percent of the original radius, the stress reaches a maximum tensile stress of about 860 mn/sq.m and then decreases to a compressive stress near the tungsten boride core. Data were presented for 203 micron diameter B/W fibers that show annealing above 900 C reduces the residual stresses. A comparison between 102 micron diameter B/W and boron on carbon (b/C) shows that the residual stresses were similar in the outer regions of the fibers, but that large differences near and in the core were observed. The effects of these residual stresses on the fracture of boron fibers were discussed.

  10. Small axial turbine stator technology program

    NASA Technical Reports Server (NTRS)

    Brockett, W.; Kozak, A.

    1982-01-01

    An experimental investigation was conducted to determine the effects of surface finish, fillet radius, inlet boundary layer thickness, and free-stream inlet turbulence level on the aerodynamic performance of a small axial flow turbine stator. The principal objective of this program was to help understand why large turbine efficiency is not maintained when a large turbine is scaled to a smaller size. The stator used in this program as a one-sixth scale of a 762 mm (30 in.) diameter stator design with 50 vanes having a vane height of 17 mm (0.666 in.) and an aspect ratio of 1.77. A comprehensive overall test matrix was used to provide a complete engineering understanding of the effects of each variable over the full range of all the other variables. The range of each variable investigated was as follows: surface finish 0.1 micro (4 micro in.) to 2.4 micro (95 micro in.); boundary layer thickness 2 to 25 percent of channel height at each wall; fillet radius 0 mm (0 in.) to 1.0 mm (.040 in.) and turbulence 2 to 12 percent.

  11. Axial 3D region of interest reconstruction using weighted cone beam BPF/DBPF algorithm cascaded with adequately oriented orthogonal butterfly filtering

    NASA Astrophysics Data System (ADS)

    Tang, Shaojie; Tang, Xiangyang

    2016-03-01

    Axial cone beam (CB) computed tomography (CT) reconstruction is still the most desirable in clinical applications. As the potential candidates with analytic form for the task, the back projection-filtration (BPF) and the derivative backprojection filtered (DBPF) algorithms, in which Hilbert filtering is the common algorithmic feature, are originally derived for exact helical and axial reconstruction from CB and fan beam projection data, respectively. These two algorithms have been heuristically extended for axial CB reconstruction via adoption of virtual PI-line segments. Unfortunately, however, streak artifacts are induced along the Hilbert filtering direction, since these algorithms are no longer accurate on the virtual PI-line segments. We have proposed to cascade the extended BPF/DBPF algorithm with orthogonal butterfly filtering for image reconstruction (namely axial CB-BPP/DBPF cascaded with orthogonal butterfly filtering), in which the orientation-specific artifacts caused by post-BP Hilbert transform can be eliminated, at a possible expense of losing the BPF/DBPF's capability of dealing with projection data truncation. Our preliminary results have shown that this is not the case in practice. Hence, in this work, we carry out an algorithmic analysis and experimental study to investigate the performance of the axial CB-BPP/DBPF cascaded with adequately oriented orthogonal butterfly filtering for three-dimensional (3D) reconstruction in region of interest (ROI).

  12. Thoracic textilomas: CT findings*

    PubMed Central

    Machado, Dianne Melo; Zanetti, Gláucia; Araujo, Cesar Augusto; Nobre, Luiz Felipe; Meirelles, Gustavo de Souza Portes; Pereira e Silva, Jorge Luiz; Guimarães, Marcos Duarte; Escuissato, Dante Luiz; Souza, Arthur Soares; Hochhegger, Bruno; Marchiori, Edson

    2014-01-01

    OBJECTIVE: The aim of this study was to analyze chest CT scans of patients with thoracic textiloma. METHODS: This was a retrospective study of 16 patients (11 men and 5 women) with surgically confirmed thoracic textiloma. The chest CT scans of those patients were evaluated by two independent observers, and discordant results were resolved by consensus. RESULTS: The majority (62.5%) of the textilomas were caused by previous heart surgery. The most common symptoms were chest pain (in 68.75%) and cough (in 56.25%). In all cases, the main tomographic finding was a mass with regular contours and borders that were well-defined or partially defined. Half of the textilomas occurred in the right hemithorax and half occurred in the left. The majority (56.25%) were located in the lower third of the lung. The diameter of the mass was ≤ 10 cm in 10 cases (62.5%) and > 10 cm in the remaining 6 cases (37.5%). Most (81.25%) of the textilomas were heterogeneous in density, with signs of calcification, gas, radiopaque marker, or sponge-like material. Peripheral expansion of the mass was observed in 12 (92.3%) of the 13 patients in whom a contrast agent was used. Intraoperatively, pleural involvement was observed in 14 cases (87.5%) and pericardial involvement was observed in 2 (12.5%). CONCLUSIONS: It is important to recognize the main tomographic aspects of thoracic textilomas in order to include this possibility in the differential diagnosis of chest pain and cough in patients with a history of heart or thoracic surgery, thus promoting the early identification and treatment of this postoperative complication. PMID:25410842

  13. Phase-transfer-catalyzed asymmetric synthesis of axially chiral anilides.

    PubMed

    Liu, Kun; Wu, Xiangfei; Kan, S B Jennifer; Shirakawa, Seiji; Maruoka, Keiji

    2013-12-01

    Catalytic asymmetric synthesis of axially chiral o-iodoanilides and o-tert-butylanilides as useful chiral building blocks was achieved by means of binaphthyl-modified chiral quaternary ammonium-salt-catalyzed N-alkylations under phase-transfer conditions. The synthetic utility of axially chiral products was demonstrated in various transformations. For example, axially chiral N-allyl-o-iodoanilide was transformed to 3-methylindoline by means of radical cyclization with high chirality transfer from axial chirality to C-centered chirality. Furthermore, stereochemical information on axial chirality in o-tert-butylanilides could be used as a template to control the stereochemistry of subsequent transformations. The transition-state structure of the present phase-transfer reaction was discussed on the basis of the X-ray crystal structure of ammonium anilide, which was prepared from binaphthyl-modified chiral ammonium bromide and o-iodoanilide. The chiral tetraalkylammonium bromide as a phase-transfer catalyst recognized the steric difference between the ortho substituents on anilide to obtain high enantioselectivity. The size and structural effects of the ortho substituents on anilide were investigated, and a wide variety of axially chiral anilides that possess various functional groups could be synthesized with high enantioselectivities. This method is the only general way to access a variety of axially chiral anilides in a highly enantioselective fashion reported to date.

  14. Solving outside-axial-field-of-view scatter correction problem in PET via digital experimentation

    NASA Astrophysics Data System (ADS)

    Andreyev, Andriy; Zhu, Yang-Ming; Ye, Jinghan; Song, Xiyun; Hu, Zhiqiang

    2016-03-01

    Unaccounted scatter impact from unknown outside-axial-field-of-view (outside-AFOV) activity in PET is an important degrading factor for image quality and quantitation. Resource consuming and unpopular way to account for the outside- AFOV activity is to perform an additional PET/CT scan of adjacent regions. In this work we investigate a solution to the outside-AFOV scatter problem without performing a PET/CT scan of the adjacent regions. The main motivation for the proposed method is that the measured random corrected prompt (RCP) sinogram in the background region surrounding the measured object contains only scattered events, originating from both inside- and outside-AFOV activity. In this method, the scatter correction simulation searches through many randomly-chosen outside-AFOV activity estimates along with known inside-AFOV activity, generating a plethora of scatter distribution sinograms. This digital experimentation iterates until a decent match is found between a simulated scatter sinogram (that include supposed outside-AFOV activity) and the measured RCP sinogram in the background region. The combined scatter impact from inside- and outside-AFOV activity can then be used for scatter correction during final image reconstruction phase. Preliminary results using measured phantom data indicate successful phantom length estimate with the method, and, therefore, accurate outside-AFOV scatter estimate.

  15. Axial penile rigidity: determinants and relation to hemodynamic parameters.

    PubMed

    Goldstein, I; Udelson, D

    1998-05-01

    Erectile dysfunction may be defined in terms of axial penile rigidity, the physical property that enables the erection to be utilized as a penetration tool during sexual activity. Erectile dysfunction occurs when inadequate axial penile rigidity results in buckling of the penile column when subjected to axial compressive loading situations during vaginal intromission. New multi-disciplinary engineering studies of penile hemodynamic and structural dynamic relationships are reviewed concerning the determinants of axial penile rigidity. Axial penile rigidity develops as a continuum during the increases in intracavernosal pressure and volume changes from the flaccid state and is influenced by intracavernosal pressure, penile tissue mechanical properties and penile geometry. Two penile tissue mechanical properties are especially relevant; cavernosal maximum volume at relatively low intracavernosal pressure, and tunical distensibility, the relative volume of the fully erect to completely flaccid pendulous penis. Two penile geometric properties are critical; the penile aspect ratio, defined as the diameter to length ratio of the pendulous penis, and the magnitude of the flaccid penile diameter. Clinically measured values of axial buckling forces in patients undergoing dynamic pharmacocavernosometry strongly correlated to theoretic-based analytic derived magnitudes of axial penile rigidity based on these above pressure, tissue and geometric determinants. Since axial penile rigidity is not exclusively dependent upon intracavernosal pressure, patients with normal erectile hemodynamics may be erroneously labelled as having psychogenic dysfunction where their true pathophysiology may be related to abnormal penile tissue properties and/or penile geometric factors. Similarly, some patients may claim sufficient rigidity for penetration, but have abnormal hemodynamic erectile function studies. They may have uniquely advantageous tissue mechanical and/or geometric properties. More

  16. CT scanning of the breast using a conventional CT scanner.

    PubMed

    Doust, B D; Milbrath, J R; Doust, V L

    1981-09-01

    Using a conventional body CT scanner, computed tomography of the breast was performed on 32 patients known to have or suspected of having breast masses. Xeromammograms were available for comparison in all cases. All mass lesions were histologically proved. Seven patients were examined prone, 25 supine. The prone position yielded pictures that resembled craniocaudal mammograms. Breast asymmetry, skin thickening, stranding from a mass to the chest wall, calcification, and axillary lymphadenopathy could be demonstrated by means of CT. The portion of the breast adjacent to the chest wall was more readily examined by means of CT than by conventional mammography. Internal mammary nodes could not be demonstrated.

  17. Multidetector CT and postprocessing in planning and assisting in minimally invasive bronchoscopic airway interventions.

    PubMed

    Nair, Arjun; Godoy, Myrna C; Holden, Emma L; Madden, Brendan P; Chua, Felix; Ost, David E; Roos, Justus E; Naidich, David P; Vlahos, Ioannis

    2012-01-01

    A widening spectrum of increasingly advanced bronchoscopic techniques is available for the diagnosis and treatment of various bronchopulmonary diseases. The evolution of computed tomography (CT)-multidetector CT in particular-has paralleled these advances. The resulting development of two-dimensional and three-dimensional (3D) postprocessing techniques has complemented axial CT interpretation in providing more anatomically familiar information to the pulmonologist. Two-dimensional techniques such as multiplanar recontructions and 3D techniques such as virtual bronchoscopy can provide accurate guidance for increasing yield in transbronchial needle aspiration and transbronchial biopsy of mediastinal and hilar lymph nodes. Sampling of lesions located deeper within the lung periphery via bronchoscopic pathways determined at virtual bronchoscopy are also increasingly feasible. CT fluoroscopy for real-time image-guided sampling is now widely available; electromagnetic navigation guidance is being used in select centers but is currently more costly. Minimally invasive bronchoscopic techniques for restoring airway patency in obstruction caused by both benign and malignant conditions include mechanical strategies such as airway stent insertion and ablative techniques such as electrocauterization and cryotherapy. Multidetector CT postprocessing techniques provide valuable information for planning and surveillance of these treatment methods. In particular, they optimize the evaluation of dynamic obstructive conditions such as tracheobronchomalacia, especially with the greater craniocaudal coverage now provided by wide-area detectors. Multidetector CT also provides planning information for bronchoscopic treatment of bronchopleural fistulas and bronchoscopic lung volume reduction for carefully selected patients with refractory emphysema.

  18. On-the-fly generation of multiplanar reformation images independent of CT scanner type.

    PubMed

    Jeong, Dong Kyun; Lee, Kyoung Ho; Kim, Bo Hyoung; Kim, Kil Joong; Kim, Young Hoon; Bajpai, Vasundhara; Shin, Yeong Gil

    2008-09-01

    We propose a system that automatically generates multiplanar reformation (MPR) images on-the-fly, which is independent of computed tomography (CT) scanner type. Triggered by digital imaging communication in medicine (DICOM) Storage Commitment or in a time threshold manner, this system generates MPR images from received thin-section CT data sets with predefined reformation parameters and then sends MPR images to DICOM stations. Users can specify the reformation parameters and the destination of the resulting MPR images for each CT study description. A pilot system was tested for 3 months. From thin-section data sets received from two 16- and one 64-detector-row CT scanners, this system generated MPR images and sent them to the picture archiving and communication system (PACS) without failure or any additional human operation. For 143 test thin-section CT studies (172-4,761 images in each study), the time to store reformatted images (axial and coronal with 5-mm thicknesses and 4-mm intervals) in PACS after the completion of the CT scan ranged from 92 to 1,772 s (mean +/- SD, 555.1 +/- 509.4).

  19. Experimental benchmarking of a Monte Carlo dose simulation code for pediatric CT

    NASA Astrophysics Data System (ADS)

    Li, Xiang; Samei, Ehsan; Yoshizumi, Terry; Colsher, James G.; Jones, Robert P.; Frush, Donald P.

    2007-03-01

    In recent years, there has been a desire to reduce CT radiation dose to children because of their susceptibility and prolonged risk for cancer induction. Concerns arise, however, as to the impact of dose reduction on image quality and thus potentially on diagnostic accuracy. To study the dose and image quality relationship, we are developing a simulation code to calculate organ dose in pediatric CT patients. To benchmark this code, a cylindrical phantom was built to represent a pediatric torso, which allows measurements of dose distributions from its center to its periphery. Dose distributions for axial CT scans were measured on a 64-slice multidetector CT (MDCT) scanner (GE Healthcare, Chalfont St. Giles, UK). The same measurements were simulated using a Monte Carlo code (PENELOPE, Universitat de Barcelona) with the applicable CT geometry including bowtie filter. The deviations between simulated and measured dose values were generally within 5%. To our knowledge, this work is one of the first attempts to compare measured radial dose distributions on a cylindrical phantom with Monte Carlo simulated results. It provides a simple and effective method for benchmarking organ dose simulation codes and demonstrates the potential of Monte Carlo simulation for investigating the relationship between dose and image quality for pediatric CT patients.

  20. Multirigid registration of MR and CT images of the cervical spine

    NASA Astrophysics Data System (ADS)

    Hu, Yangqiu; Haynor, David R.

    2004-05-01

    We present our work on fusion of MR and CT images of the cervical spine. To achieve the required registration accuracy of approximately 1mm, the spine is treated as a collection of rigid vertebrae, and a separate rigid body transformation applied to each (Hawkes). This in turn requires segmentation of the CT datasets into separate vertebral images, which is difficult because the narrow planes separating adjacent vertebrae are parallel to the axial plane of the CT scans. We solve this problem by evolving all the vertebral contours simultaneously using a level set method, and use contour competition to estimate the position of the vertebral edges when a clean separation between adjacent vertebrae is not seen. Contour competition is based in turn on the vertical scan principle: no part of a given vertebra is vertically below any part of an inferior vertebra. Once segmentation is complete, the individual rigid body transforms are then estimated using mutual information maximization, and the CT images of the vertebrae superimposed on the MR scans. The resultant fused images contain the bony detail of CT and the soft tissue discrimination of MR and appear to be diagnostically equivalent, or superior, to CT myelograms. A formal test of these conclusions is planned for the next phase of our work.

  1. Historical variation of the geomagnetic axial dipole

    NASA Astrophysics Data System (ADS)

    Finlay, Christopher C.

    2008-09-01

    The geomagnetic axial dipole (hereinafter denoted g10) is the largest component of our planet's magnetic field. Its magnitude determines the morphology of solar-terrestrial electrical current systems and it is the most fundamental diagnostic property of the core-generated geodynamo. Elucidating past and future variations of g10(t) is consequently of central importance in geomagnetism. Previous historical geomagnetic field models, such as gufm1 of Jackson et al. [Jackson, A., Jonkers, A.R.T., Walker, M.R., 2000. Four centuries of geomagnetic secular variation from historical records. Philos. Trans. R. Soc. Lond. A 358, 957-990], used direct observations to constrain g10(t) only after 1840 A.D.; before this time a crude linear extrapolation of the post-1840 A.D. rate of change (15 nT/year) was employed. In this contribution I construct historical field models with g10(t) instead constrained from 1590 A.D. to 1840 A.D. by an archaeointensity dataset compiled by Korte et al. [Korte, M., Genevey, A., Constable, C.G., Frank, U., Schnepp, E., 2005. Continuous geomagnetic field models for the past 7 millennia. 1. A new global data compilation. Geochem. Geophys. Geosyst. 6, doi:10.1029/2004GC000800]. A range of possible linear models of the form g10(t)=g10(1840)+β(t-1840) are first explored; β=2.74±42.32 nT/year is found to explain the archaeointensity dataset with maximum likelihood, consistent with the recent findings of Gubbins et al. [Gubbins, D., Jones, A.L., Finlay, C.C., 2006. Fall in Earth's magnetic field is erratic. Science 312, 900-902]. Relaxing the linear constraint in an effort to find more physically plausible models, I find it is necessary to artificially increase the weight given to the archaeointensity data in order to obtain acceptable models. Despite satisfactorily explaining both the historical and archaeointensity data, and possessing reasonable spatial and temporal complexity, such free evolution models perform worse than the simpler linearly

  2. A Model for Axial Magnetic Bearings Including Eddy Currents

    NASA Technical Reports Server (NTRS)

    Kucera, Ladislav; Ahrens, Markus

    1996-01-01

    This paper presents an analytical method of modelling eddy currents inside axial bearings. The problem is solved by dividing an axial bearing into elementary geometric forms, solving the Maxwell equations for these simplified geometries, defining boundary conditions and combining the geometries. The final result is an analytical solution for the flux, from which the impedance and the force of an axial bearing can be derived. Several impedance measurements have shown that the analytical solution can fit the measured data with a precision of approximately 5%.

  3. Fluorescence Axial Localization with Nanometer Accuracy and Precision

    SciTech Connect

    Li, Hui; Yen, Chi-Fu; Sivasankar, Sanjeevi

    2012-06-15

    We describe a new technique, standing wave axial nanometry (SWAN), to image the axial location of a single nanoscale fluorescent object with sub-nanometer accuracy and 3.7 nm precision. A standing wave, generated by positioning an atomic force microscope tip over a focused laser beam, is used to excite fluorescence; axial position is determined from the phase of the emission intensity. We use SWAN to measure the orientation of single DNA molecules of different lengths, grafted on surfaces with different functionalities.

  4. Nonmechanical axial scanning laser Doppler velocimeter with directional discrimination.

    PubMed

    Maru, Koichi; Hata, Takahiro

    2012-07-10

    An axial scanning laser Doppler velocimeter (LDV) with directional discrimination not requiring any moving mechanism in its probe is proposed. The proposed LDV utilizes frequency shift induced by acousto-optic modulators (AOMs) for discriminating the direction of velocity. The measurement position is axially scanned by changing the wavelength of the light input to the probe. The experimental result reveals that both the axial scan and the directional discrimination can be realized by using the proposed method without any moving element in the probe.

  5. High Power Co-Axial Coupler

    SciTech Connect

    Johnson, Rolland; Neubauer, Michael

    2013-08-14

    A superconducting RF (SRF) power coupler capable of handling 500 kW CW RF power at 750 MHz is required for present and future storage rings and linacs. There are over 35 coupler designs for SRF cavities ranging in frequency from 325 to 1500 MHz. Coupler windows vary from cylinders to cones to disks and RF power couplers will always be limited by the ability of ceramic windows and their matching systems to withstand the stresses due to non-uniform heating from dielectric and wall losses, multipactor, and mechanical flexure. In the Phase II project, we built a double window coaxial system with materials that would not otherwise be useable due to individual VSWRs. Double window systems can be operated such that one is cold (LN2) and one is warm. They can have different materials and still have a good match without using matching elements that create problematic multipactor bands. The match of the two windows will always result from the cancellation of the two window’s reflections when they are located approximately a quarter wavelength apart or multiples of a quarter wavelength. The window assemblies were carefully constructed to put the window material and its braze joint in compression at all times. This was done using explosion bonding techniques which allow for inexpensive fabrication of the vacuum / compression ring out of stainless steel with copper plating applied to the inner surface. The EIA 3-1/8” double window assembly was then successfully baked out and tested to 12 kW in a 3-1/8” co-axial system. The thermal gradient across the window was measured to be 90 C which represents about 15 ksi tensile stress in an uncompressed window. In our design the compression was calculated to be about 25 ksi, so the net compressive force was 5 ksi at full power.

  6. Revealing atropisomer axial chirality in drug discovery.

    PubMed

    LaPlante, Steven R; Edwards, Paul J; Fader, Lee D; Jakalian, Araz; Hucke, Oliver

    2011-03-07

    An often overlooked source of chirality is atropisomerism, which results from slow rotation along a bond axis due to steric hindrance and/or electronic factors. If undetected or not managed properly, this time-dependent chirality has the potential to lead to serious consequences, because atropisomers can be present as distinct enantiomers or diastereoisomers with their attendant different properties. Herein we introduce a strategy to reveal and classify compounds that have atropisomeric chirality. Energy barriers to axial rotation were calculated using quantum mechanics, from which predicted high barriers could be experimentally validated. A calculated rotational energy barrier of 20 kcal mol(-1) was established as a suitable threshold to distinguish between atropisomers and non-atropisomers with a prediction accuracy of 86%. This methodology was applied to subsets of drug databases in the course of which atropisomeric drugs were identified. In addition, some drugs were exposed that were not yet known to have this chiral attribute. The most valuable utility of this tool will be to predict atropisomerism along the drug discovery pathway. When used in concert with our compound classification scheme, decisions can be made during early discovery stages such as "hit-to-lead" and "lead optimization," to foresee and validate the presence of atropisomers and to exercise options of removing, further stabilizing, or rendering the chiral axis of interest more freely rotatable via SAR design, thereby decreasing this potential liability within a compound series. The strategy can also improve drug development plans, such as determining whether a drug or series should be developed as a racemic mixture or as an isolated single compound. Moreover, the work described herein can be extended to other chemical fields that require the assessment of potential chiral axes.

  7. Comparison between blinded and partially blinded detection of gastric cancer with multidetector CT using surgery and endoscopic submucosal dissection as reference standards.

    PubMed

    Kim, H J; Lee, D H; Ko, Y T

    2010-08-01

    The aim of this study is to compare blinded with partially blinded detection of gastric cancer with multidetector (MD) CT by using surgery and endoscopic submucosal dissection (ESD) as reference standards. 44 patients with gastric cancer underwent MDCT with air as an oral contrast agent. Surgery was performed on 37 patients, ESD on six and surgery after ESD on one. To provide comparison cases of blinded evaluation, 38 MDCT examinations were added for cases where no focal gastric lesion was seen on endoscopy. Two radiologists, blinded to the presence, number and location of the tumours, evaluated axial and axial plus multiplanar reformation (MPR) images of 82 MDCT examinations with or without gastric cancer. For partially blinded evaluation, the same radiologists, blinded to the location and number of tumours, evaluated axial and axial plus MPR images of 44 MDCT examinations of gastric cancer. Differences in assessment were resolved by consensus. 45 gastric cancers were found in surgical and ESD specimens. Detection rates of gastric cancer from axial and axial plus MPR images during blinded evaluation and from axial and axial plus MPR images during partially blinded evaluation were 62% (28/45), 64% (29/45), 64% (29/45) and 71% (32/45), respectively. There was no statistical significance for the comparison between blinded and partially blinded detection rates of gastric cancer. The detection rate of gastric cancer with MDCT during blinded evaluation showed no specific difference compared with the detection rate of gastric cancer with MDCT during partially blinded evaluation.

  8. Helical CT in emergency radiology.

    PubMed

    Novelline, R A; Rhea, J T; Rao, P M; Stuk, J L

    1999-11-01

    Today, a wide range of traumatic and nontraumatic emergency conditions are quickly and accurately diagnosed with helical computed tomography (CT). Many traditional emergency imaging procedures have been replaced with newer helical CT techniques that can be performed in less time and with greater accuracy, less patient discomfort, and decreased cost. The speed of helical technology permits CT examination of seriously ill patients in the emergency department, as well as patients who might not have been taken to CT previously because of the length of the examinations of the past. Also, helical technology permits multiple, sequential CT scans to be quickly obtained in the same patient, a great advance for the multiple-trauma patient. Higher quality CT examinations result from decreased respiratory misregistration, enhanced intravenous contrast material opacification of vascular structures and parenchymal organs, greater flexibility in image reconstruction, and improved multiplanar and three-dimensional reformations. This report summarizes the role and recommended protocols for the helical CT diagnosis of thoracic aortic trauma; aortic dissection; pulmonary embolism; acute conditions of the neck soft tissues; abdominal trauma; urinary tract stones; appendicitis; diverticulitis; abdominal aortic aneurysm; fractures of the face, spine, and extremities; and acute stroke.

  9. MULTIMODALITY IMAGING: BEYOND PET/CT AND SPECT/CT

    PubMed Central

    Cherry, Simon R.

    2009-01-01

    Multimodality imaging with PET/CT and SPECT/CT has become commonplace in clinical practice and in preclinical and basic medical research. Do other combinations of imaging modalities have a similar potential to impact medical science and clinical medicine? The combination of PET or SPECT with MRI is an area of active research at the present time, while other, perhaps less obvious combinations, including CT/MR and PET/optical also are being studied. In addition to the integration of the instrumentation, there are parallel developments in synthesizing imaging agents that can be viewed by multiple imaging modalities. Is the fusion of PET and SPECT with CT the ultimate answer in multimodality imaging, or is it just the first example of a more general trend towards harnessing the complementary nature of the different modalities on integrated imaging platforms? PMID:19646559

  10. Characterization of multiphase fluid flow during air-sparged hydrocyclone flotation by x-ray CT. Fourteenth quarterly report, 14 November 1993--13 February 1994

    SciTech Connect

    Miller, J.D.

    1994-08-10

    During this quarter of the DOE project, ``Characterization of Multiphase Fluid Flow During Air-Sparged Hydrocyclone Flotation``, efforts were made to correlate the x-ray CT measurements with the flotation experiments reported in the last. quarterly report. In this regard the axial view of the flow regimes in the ASH during steady state operation were constructed from the radial density profiles as revealed by x-ray CT measurements. By studying the characteristics of the flow regimes from these axial views and relating them with flotation recovery data, a more detailed understanding of ASH flotation was possible. Construction of the axial view of the flow regimes and the effect of two operating variables, dimensionless area ratio (A* = overflow opening area/underflow opening area) and percent solids in the feed, are reported in this quarterly report.

  11. Characterization of multiphase fluid flow during air-sparged hydrocyclone flotation by x-ray CT. Fifteenth quarterly report, 14 February 1994--13 May 1994

    SciTech Connect

    Miller, J.D.

    1994-08-10

    During this quarter of the DOE project, ``Characterization of Multiphase Fluid Flow During Air-Sparged Hydrocyclone Flotation``, the x-ray CT measurements were correlated with the results from the flotation experiments reported in the 13th quarterly report. In this regard the axial view of the flow regimes in the ASH during steady state operation were constructed from the radial density profiles as revealed by x-ray CT measurements. Construction of the axial view of the flow regimes was explained in the last quarterly report. By studying the characteristics of the flow regimes from these axial views and relating them with flotation recovery data, a phenomenological description of ASH flotation was possible. The effect of two operating variables, inlet pressure and dimensionless flow rate ratio (A* = air flow rate/slurry flow rate), are reported in this quarterly report.

  12. 22. Axial view along north cell corridor, cells at right; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Axial view along north cell corridor, cells at right; view to southwest, 65mm lens with electronic flash illumination. - Tule Lake Project Jail, Post Mile 44.85, State Route 139, Newell, Modoc County, CA

  13. Radial breathing mode of carbon nanotubes subjected to axial pressure.

    PubMed

    Lei, Xiao-Wen; Ni, Qing-Qing; Shi, Jin-Xing; Natsuki, Toshiaki

    2011-08-11

    In this paper, a theoretical analysis of the radial breathing mode (RBM) of carbon nanotubes (CNTs) subjected to axial pressure is presented based on an elastic continuum model. Single-walled carbon nanotubes (SWCNTs) are described as an individual elastic shell and double-walled carbon nanotubes (DWCNTs) are considered to be two shells coupled through the van der Waals force. The effects of axial pressure, wave numbers and nanotube diameter on the RBM frequency are investigated in detail. The validity of these theoretical results is confirmed through the comparison of the experiment, calculation and simulation. Our results show that the RBM frequency is linearly dependent on the axial pressure and is affected by the wave numbers. We concluded that RBM frequency can be used to characterize the axial pressure acting on both ends of a CNT.

  14. 12. Axial view to north of south portal of truss ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Axial view to north of south portal of truss span. Repaired compression and sway brace members clearly visible. - Stanislaus River Bridge, Atchison, Topeka & Santa Fe Railway at Stanislaus River, Riverbank, Stanislaus County, CA

  15. Axial field shaping under high-numerical-aperture focusing

    NASA Astrophysics Data System (ADS)

    Jabbour, Toufic G.; Kuebler, Stephen M.

    2007-03-01

    Kant reported [J. Mod. Optics47, 905 (2000)] a formulation for solving the inverse problem of vector diffraction, which accurately models high-NA focusing. Here, Kant's formulation is adapted to the method of generalized projections to obtain an algorithm for designing diffractive optical elements (DOEs) that reshape the axial point-spread function (PSF). The algorithm is applied to design a binary phase-only DOE that superresolves the axial PSF with controlled increase in axial sidelobes. An 11-zone DOE is identified that axially narrows the PSF central lobe by 29% while maintaining the sidelobe intensity at or below 52% of the peak intensity. This DOE could improve the resolution achievable in several applications without significantly complicating the optical system.

  16. 2. AXIAL VIEW OF THE MAIN EQUIPMENT ROOM IN BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. AXIAL VIEW OF THE MAIN EQUIPMENT ROOM IN BUILDING 408, LOOKING WEST-SOUTHWEST. - Mill Valley Air Force Station, Operations Building & Annex, East Ridgecrest Boulevard, Mount Tamalpais, Mill Valley, Marin County, CA

  17. Axial mesodermal dysplasia complex: a new case with parental consanguinity.

    PubMed

    Mota, C R; Azevedo, M; Rocha, G; Manuela, F; Coelho, R; Lima, M R

    2000-01-01

    A female is described with axial mesodermal dysplasia complex (AMDC) born to a consanguineous couple. This is thought to be the first description of a patient with AMDC born to consanguineous parents.

  18. Errors in CT colonography.

    PubMed

    Trilisky, Igor; Ward, Emily; Dachman, Abraham H

    2015-10-01

    CT colonography (CTC) is a colorectal cancer screening modality which is becoming more widely implemented and has shown polyp detection rates comparable to those of optical colonoscopy. CTC has the potential to improve population screening rates due to its minimal invasiveness, no sedation requirement, potential for reduced cathartic examination, faster patient throughput, and cost-effectiveness. Proper implementation of a CTC screening program requires careful attention to numerous factors, including patient preparation prior to the examination, the technical aspects of image acquisition, and post-processing of the acquired data. A CTC workstation with dedicated software is required with integrated CTC-specific display features. Many workstations include computer-aided detection software which is designed to decrease errors of detection by detecting and displaying polyp-candidates to the reader for evaluation. There are several pitfalls which may result in false-negative and false-positive reader interpretation. We present an overview of the potential errors in CTC and a systematic approach to avoid them.

  19. Axially astigmatic surfaces: different types and their properties

    NASA Astrophysics Data System (ADS)

    Malacara-Doblado, Daniel; Malacara-Hernandez, Daniel; Garcia-Marquez, Jorge L.

    1996-12-01

    Axially astigmatic surfaces have different curvatures in orthogonal diameters. Toroidal and spherocylindrical optical surfaces are two mathematically different special cases of axially astigmatic surfaces as noted by Menchaca and Malacara (1986), but they are almost identical in the vicinity of the optical axis. The different between these two surfaces increases when the distance to the optical axis increases. We study the general properties of astigmatic surfaces and some special interesting cases.

  20. The research on flow pulsation characteristics of axial piston pump

    NASA Astrophysics Data System (ADS)

    Wang, Bingchao; Wang, Yulin

    2017-01-01

    The flow pulsation is an important factor influencing the axial piston pump performance. In this paper we implement modeling and simulation of the axial piston pump with AMESim software to explore the flow pulsation characteristics under various factors . Theory analysis shows the loading pressure, angular speed, piston numbers and the accumulator impose evident influence on the flow pulsation characteristics. This simulation and analysis can be used for reducing the flow pulsation rate via properly setting the related factors.

  1. Update on the PWR axial burnup profile database

    SciTech Connect

    Cacciapouti, R.F.; Volkinburg, S.V.

    1995-12-01

    A pressurized water reactor database was developed to evaluate the axial burnup profiles of various reactor types. The data showed that the various types exhibit similar behavior, especially at the top and bottom of the assembly. From the existing data, bounding axial burnup profiles can be developed to envelope the various pressurized water reactor assembly deigns. The database encompasses most of the PWR fuel designs and contains sufficient data to provide reliable statistics.

  2. Comparison of Image Quality, Diagnostic Accuracy and Radiation Dose Between Flash Model and Retrospective ECG-Triggered Protocols in Dual Source Computed Tomography (DSCT) in Congenital Heart Diseases

    PubMed Central

    Wang, Rong; Xu, Xiang-Jiu; Huang, Gang; Zhou, Xing; Zhang, Wen-Wen; Ma, Ya-Qiong; Zuo, Xiao-na

    2017-01-01

    Summary Background Dual source computed tomography (DSCT) plays an important role in the diagnosis of congenital heart diseases (CHD). However, the issue of radiation-related side effects constitutes a wide public concern. The aim of the study was to explore the differences in diagnostic accuracy, radiation dose and image quality between a prospectively ECG – triggered high – pitch spiral acquisition (flash model) and a retrospective ECG-gated protocol of DSCT used for the detection of CHD. Material/Methods The study included 58 patients with CHD who underwent a DSCT examination, including two groups of 29 patients in each protocol. Then, both subjective and objective image quality, diagnostic accuracy and radiation dose were compared between the two protocols. Results The image quality and the total as well as partial diagnostic accuracy did not differ significantly between the protocols. The radiation dose in the flash model was obviously lower than that in the retrospective model (P<0.05). Conclusions Compared to the retrospective protocol, the flash model can significantly reduce the dose of radiation, while maintaining both diagnostic accuracy and image quality. PMID:28344686

  3. PRELIMINARY DESIGN ANALYSIS OF AXIAL FLOW TURBINES

    NASA Technical Reports Server (NTRS)

    Glassman, A. J.

    1994-01-01

    A computer program has been developed for the preliminary design analysis of axial-flow turbines. Rapid approximate generalized procedures requiring minimum input are used to provide turbine overall geometry and performance adequate for screening studies. The computations are based on mean-diameter flow properties and a stage-average velocity diagram. Gas properties are assumed constant throughout the turbine. For any given turbine, all stages, except the first, are specified to have the same shape velocity diagram. The first stage differs only in the value of inlet flow angle. The velocity diagram shape depends upon the stage work factor value and the specified type of velocity diagram. Velocity diagrams can be specified as symmetrical, zero exit swirl, or impulse; or by inputting stage swirl split. Exit turning vanes can be included in the design. The 1991 update includes a generalized velocity diagram, a more flexible meanline path, a reheat model, a radial component of velocity, and a computation of free-vortex hub and tip velocity diagrams. Also, a loss-coefficient calibration was performed to provide recommended values for airbreathing engine turbines. Input design requirements include power or pressure ratio, mass flow rate, inlet temperature and pressure, and rotative speed. The design variables include inlet and exit diameters, stator angle or exit radius ratio, and number of stages. Gas properties are input as gas constant, specific heat ratio, and viscosity. The program output includes inlet and exit annulus dimensions, exit temperature and pressure, total and static efficiencies, flow angles, blading angles, and last stage absolute and relative Mach numbers. This program is written in FORTRAN 77 and can be ported to any computer with a standard FORTRAN compiler which supports NAMELIST. It was originally developed on an IBM 7000 series computer running VM and has been implemented on IBM PC computers and compatibles running MS-DOS under Lahey FORTRAN, and

  4. Greening America's Capitals - Hartford, CT

    EPA Pesticide Factsheets

    This Greening America's Capitals report gives Hartford, CT, a new vision for Capitol Avenue that highlights existing assets and fills in gaps along the mile-long area of focus and into the surrounding neighborhoods.

  5. Multiplanar CT of the spine

    SciTech Connect

    Rothman, S.L.G.; Glenn, W.V. Jr.

    1986-01-01

    This is an illustrated text on computed tomography (CT) of the lumbar spine with an emphasis on the role and value of multiplanar imaging for helping determine diagnoses. The book has adequate discussion of scanning techniques for the different regions, interpretations of various abnormalities, degenerative disk disease, and different diagnoses. There is a 50-page chapter on detailed sectional anatomy of the spine and useful chapters on the postoperative spine and the planning and performing of spinal surgery with CT multiplanar reconstruction. There are comprehensive chapters on spinal tumors and trauma. The final two chapters of the book are devoted to CT image processing using digital networks and CT applications of medical computer graphics.

  6. CT Perfusion of the Head

    MedlinePlus

    ... ray beam follows a spiral path. A special computer program processes this large volume of data to create ... process. Nearly all CT scanners now have special computer programs that help to increase image quality at lower ...

  7. CT Demonstration of Caput Medusae

    ERIC Educational Resources Information Center

    Weber, Edward C.; Vilensky, Joel A.

    2009-01-01

    Maximum intensity and volume rendered CT displays of caput medusae are provided to demonstrate both the anatomy and physiology of this portosystemic shunt associated with portal hypertension. (Contains 2 figures.)

  8. Adrenal cortex dysfunction: CT findings

    SciTech Connect

    Huebener, K.H.; Treugut, H.

    1984-01-01

    The computed tomographic appearance of the adrenal gland was studied in 302 patients with possible endocrinologic disease and 107 patients undergoing CT for nonendocrinologic reasons. Measurements of adrenal size were also made in 100 adults with no known adrenal pathology. CT proved to be a sensitive diagnostic tool in combination with clinical studies. When blood hormone levels are increased, CT can differentiate among homogeneous organic hyperplasia, nodular hyperplasia, benign adenoma, and malignant cortical adenoma. When blood hormone levels are decreased, CT can demonstrate hypoplasia or metastatic tumorous destruction. Calcifications can be demonstrated earlier than on plain radiographs. When hormone elimination is increased, the morphologic substrate can be identified; tumorous changes can be localized and infiltration of surrounding organs recognized.

  9. Children's (Pediatric) CT (Computed Tomography)

    MedlinePlus Videos and Cool Tools

    ... What are the limitations of Children's CT? A person who is very large may not fit into ... facility staff and/or your insurance provider to get a better understanding of the possible charges you ...

  10. CT angiography - head and neck

    MedlinePlus

    ... medlineplus.gov/ency/article/007677.htm CT angiography - head and neck To use the sharing features on this page, ... create pictures of the blood vessels in the head and neck. How the Test is Performed You will be ...

  11. Multiplanar CT of the spine

    SciTech Connect

    Rothman, S.L.G.; Glenn, W.V.

    1985-01-01

    This book contains 16 chapters. Some of the topics are: CT of the Sacrum, The Postoperative Spine, Film Organizations and Case Reporting, Degeneration and Disc Disease of the Intervertebral Joint, Lumbar Spinal Stenosis, and Cervical and Thoracic Spine.

  12. A tonsillolith seen on CT.

    PubMed

    Espe, B J; Newmark, H

    1992-01-01

    A case of a large tonsillolith visualized by computerized tomography is presented. Although otolaryngologists are well aware of this entity, few radiologists are. The importance of distinguishing tonsilloliths from other structures by CT scan is discussed.

  13. Liver echinococcus - CT scan (image)

    MedlinePlus

    This upper abdominal CT scan shows multiple cysts in the liver, caused by dog tapeworm (echinococcus). Note the large circular cyst (seen on the left side of the screen) and multiple smaller cysts throughout ...

  14. X-ray snapshots for metalloporphyrin axial ligation

    SciTech Connect

    Chen, L. X.; Zhang, X.; Wasinger, E. C.; Lockard, J. V.; Stickrath, A. B.; Mara, M. W.; Attenkofer, K.; Jennings, G.; Smolentsev, G.; Soldatov, A.

    2010-01-01

    Axial ligation mechanisms of a metalloporphyrin, nickel(II) tetramesitylporphyrin (NiTMP), were investigated by static and transient X-ray absorption spectroscopy at Ni K-edge (8.333 keV). A surprisingly broad (i.e. {approx}1.4 eV) linewidth for the 1s {yields} 3d{sub x2-y2} transition in the ground state was attributed to strong geometry dependent 3d molecular orbital (MO) energies due to coexisting conformers in solution. The broad distribution of 3d MO energy levels enables transient degeneracy of the 3d{sub z2} and 3d{sub x2-y2} MOs to produce a temporary vacancy in the 3d{sub z2} MO which favors axial ligation. Photoexcitation also induces the vacancy in the 3d{sub z2} MO, leading to a more than two-fold enhancement in the axial ligated species. Therefore, a unified axial ligation mechanism for both the ground and excited state is proposed based on the elucidation of the excited state structural dynamics, which will have a broad impact in understanding and controlling axial ligation in enzymatic reactions and molecular catalysis involving transient axial ligation.

  15. [Changes in axial length after scleral buckling surgery].

    PubMed

    Hayashi, H; Hayashi, K; Nakao, F; Hayashi, F

    1996-04-01

    The eye lengthens after scleral buckling surgery for retinal detachment. We investigated the changes in axial length and refraction after scleral buckling. A total of 89 eyes from 88 patients which were all scheduled to undergo scleral buckling were included in this study. The eyes were classified into four groups based on the type of buckling procedures:1 local buckling, 2 encircling, 3 encircling with vitrectomy, and 4 encircling with local buckling. We examined the axial length of these eyes using ultrasonography, preoperatively and at 1, 3, and 6 months postoperatively. The refractive changes were also examined. Depending on the type of scleral buckling procedure employed, the eyes in Groups 2, 3, and 4 clearly lengthened, but those of Group 1 did not. The amount of axial lengthening in Groups 2, 3, and 4 was significantly greater than in Group 1 at 3 and 6 months after surgery. In the spherical equivalent, a myopic shift occurred in the eyes in Groups 2, 3, and 4, and this shift was significantly greater than in Group 1 In addition, the correlation between the extent of axial lengthening and myopic shift was significant. In conclusion, the axial length increases with a myopic shift due to encircling, whereas local buckling changed the axial length only slightly.

  16. Active axial spondyloarthritis: potential role of certolizumab pegol

    PubMed Central

    Ranatunga, Sriya; Miller, Anne V

    2014-01-01

    The axial spondyloarthropathies are a group of chronic inflammatory diseases that predominantly affect the axial joints. This group includes ankylosing spondylitis and nonradiographic axial spondyloarthropathy. While the pathogenesis of axial spondyloarthropathies is not clear, immunologically active tissues primarily include the entheses, ie, the areas where ligaments, tendons, and joint capsules attach to bone and to the annulus fibrosis at the vertebrae. One of the major mediators of the immune response in this group of diseases is tumor necrosis factor-alpha (TNFα). Blockade of TNFα results in reduced vascularity and inflammatory cell infiltration in the synovial tissues of affected joints. Certolizumab pegol (CZP) is an Fc-free, PEGylated anti-TNFα monoclonal antibody. CZP has unique properties that differ from other available TNFα inhibitors by virtue of its lack of an Fc region, which minimizes potential Fc-mediated effects, and its PEGylation, which improves drug pharmacokinetics and bioavailability. It has been shown in clinical trials that CZP improves patient outcomes and reduces inflammation in the sacroiliac joints and spine in both ankylosing spondylitis and nonradiographic axial spondyloarthropathies. These data support CZP as a treatment option for axial spondyloarthropathies. PMID:24611014

  17. Reactive control of subsonic axial fan noise in a duct.

    PubMed

    Liu, Y; Choy, Y S; Huang, L; Cheng, L

    2014-10-01

    Suppressing the ducted fan noise at low frequencies without varying the flow capacity is still a technical challenge. This study examines a conceived device consisting of two tensioned membranes backed with cavities housing the axial fan for suppression of the sound radiation from the axial fan directly. The noise suppression is achieved by destructive interference between the sound fields from the axial fan of a dipole nature and sound radiation from the membrane via vibroacoustics coupling. A two-dimensional model with the flow effect is presented which allows the performance of the device to be explored analytically. The air flow influences the symmetrical behavior and excites the odd in vacuo mode response of the membrane due to kinematic coupling. Such an asymmetrical effect can be compromised with off-center alignment of the axial fan. Tension plays an important role to sustain the performance to revoke the deformation of the membrane during the axial fan operation. With the design of four appropriately tensioned membranes covered by a cylindrical cavity, the first and second blade passage frequencies of the axial fan can be reduced by at least 20 dB. The satisfactory agreement between experiment and theory demonstrates that its feasibility is practical.

  18. Regularization Designs for Uniform Spatial Resolution and Noise Properties in Statistical Image Reconstruction for 3D X-ray CT

    PubMed Central

    Cho, Jang Hwan; Fessler, Jeffrey A.

    2014-01-01

    Statistical image reconstruction methods for X-ray computed tomography (CT) provide improved spatial resolution and noise properties over conventional filtered back-projection (FBP) reconstruction, along with other potential advantages such as reduced patient dose and artifacts. Conventional regularized image reconstruction leads to spatially variant spatial resolution and noise characteristics because of interactions between the system models and the regularization. Previous regularization design methods aiming to solve such issues mostly rely on circulant approximations of the Fisher information matrix that are very inaccurate for undersampled geometries like short-scan cone-beam CT. This paper extends the regularization method proposed in [1] to 3D cone-beam CT by introducing a hypothetical scanning geometry that helps address the sampling properties. The proposed regularization designs were compared with the original method in [1] with both phantom simulation and clinical reconstruction in 3D axial X-ray CT. The proposed regularization methods yield improved spatial resolution or noise uniformity in statistical image reconstruction for short-scan axial cone-beam CT. PMID:25361500

  19. Regularization designs for uniform spatial resolution and noise properties in statistical image reconstruction for 3-D X-ray CT.

    PubMed

    Cho, Jang Hwan; Fessler, Jeffrey A

    2015-02-01

    Statistical image reconstruction methods for X-ray computed tomography (CT) provide improved spatial resolution and noise properties over conventional filtered back-projection (FBP) reconstruction, along with other potential advantages such as reduced patient dose and artifacts. Conventional regularized image reconstruction leads to spatially variant spatial resolution and noise characteristics because of interactions between the system models and the regularization. Previous regularization design methods aiming to solve such issues mostly rely on circulant approximations of the Fisher information matrix that are very inaccurate for undersampled geometries like short-scan cone-beam CT. This paper extends the regularization method proposed in to 3-D cone-beam CT by introducing a hypothetical scanning geometry that helps address the sampling properties. The proposed regularization designs were compared with the original method in with both phantom simulation and clinical reconstruction in 3-D axial X-ray CT. The proposed regularization methods yield improved spatial resolution or noise uniformity in statistical image reconstruction for short-scan axial cone-beam CT.

  20. 68Ga PSMA PET/CT in a Rare Case of Metastatic Adenocarcinoma Prostate Presenting as Numb Chin Syndrome.

    PubMed

    Sasikumar, Arun; Joy, Ajith; Pillai, M R A; Gopal, Renuka; Thomas, Boben

    2017-03-01

    A 68-year-old man presented with right-side facial numbness. MRI showed an extra-axial mass infiltrating the right temporal bone. It was debulked surgically, and histopathology revealed metastatic adenocarcinoma. Ga PSMA PET/CT done in view of increased PSA levels and clinically suspicious hard lesion in prostate showed primary lesion in left side of prostate with metastases to the right temporal bone. Primary carcinoma of the prostate and metastases to the right temporal bone were proven histopathologically. Our case highlights the usefulness of Ga PSMA PET/CT in identifying the primary site in suspected prostate cancer and mapping the metastatic sites.

  1. Mapping AUV Survey of Axial Seamount

    NASA Astrophysics Data System (ADS)

    Thomas, H.; Caress, D.; Conlin, D.; Clague, D.; Paduan, J.; Butterfield, D.; Chadwick, W.; Tucker, P.

    2006-12-01

    In late August and early September 2006, the MBARI Mapping Autonomous Underwater Vehicle (AUV) was deployed for 5 missions on Axial Seamount during a NOAA NeMO cruise on the R/V Thompson. The objective of the survey was to determine the geologic history of the summit of Axial Seamount using high resolution multibeam, sidescan, and sub-bottom profiler data. The Mapping AUV is a torpedo-shaped, 6000 m rated vehicle designed and constructed by MBARI. The vehicle is equipped with a 200 kHz multibeam sonar, 110 kHz and 410 kHz chirp sidescan sonar, and a 2-16 kHz sweep chirp sub-bottom profiler. The multibeam provides a 120-degree swath with 0.94 degree by 0.94 degree beam resolution. The endurance of the AUV is eight hours at 3 knots. Navigation derives from an inertial navigation system (INS) incorporating a ring laser gyro aided by GPS at the surface and by velocity-over- ground observations from a Doppler velocity log (DVL) when within 130 m of the seafloor. A navigational precision of 0.05 percent of distance traveled is achieved with continuous DVL bottom lock. An acoustic modem allows surface aiding of navigation during deep descents. The AUV ran two types of missions: those on the rim of the caldera were run at 90 m altitude with a line spacing of 250 m and those on the caldera floor were run at 50 m altitude with a line spacing of 150 or 175 m. The surveys covered most of 1998 lava flow on the south rim of the caldera and northern part of the south rift zone, the southern region of the caldera floor where hydrothermal vents are common, the northeast rim of the caldera where volcaniclastic deposits related to caldera collapse drape the surface, the north rift zone, and the northern portion of the caldera floor. The low-altitude maps have a resolution of 1 m, so large individual lava pillars and hydrothermal chimneys can be seen, fissures stand out clearly, and the regions of collapsed lobate flows and lava channels are prominent. Many of the flows, including the

  2. Primary lower extremity lymphedema: CT diagnosis

    SciTech Connect

    Gamba, J.L.; Silverman, P.M.; Ling, D.; Dunnick, N.R.; Korobkin, M.

    1983-10-01

    The CT findings of two cases of primary lymphedema of the lower extremities are presented. CT showed a coarse, nonenhancing, reticular pattern in an enlarged subcutaneous compartment. CT excluded the diagnosis of secondary lymphedema from an obstructing mass by demonstrating a normal retroperitoneum and pelvis. The CT findings are correlated with pedal lymphangiograms.

  3. Primary epiploic appendagitis: CT diagnosis.

    PubMed

    Sandrasegaran, Kumaresan; Maglinte, Dean D; Rajesh, Arumugam; Akisik, Fatih M

    2004-08-01

    The purpose of this study was to analyze the CT signs of primary epiploic appendagitis. A retrospective search of the CT database over 12 months for this diagnosis revealed 11 cases. The clinical findings were recorded. Softcopy CT images were reviewed by two experienced abdominal radiologists (KS, DM) for location of lesion, size, shape, presence of central hyperdense focus, degree of bowel wall thickening, mass effect, and ancillary signs. Abdominal pain was the primary symptom in all patients. Preliminary diagnoses were appendicitis (n=2), diverticulitis (n=5), pancreatitis (n=1), ovarian lesion (n=1), or unknown (n=2). Abdominal examination and white blood cell count were uninformative. CT examination revealed a solitary (n=11), ovoid (n=9) fatty lesion with some soft tissue stranding adjacent to the left colon (n=6), transverse colon (n=3), or right colon (n=2). Central hyperdensity (n=5), mild bowel wall thickening (n=2), and parietal peritoneal thickening (n=4) were also seen. In 4 patients the lesions were not visible on follow-up CT examination performed 23-184 days later. Primary epiploic appendagitis can clinically mimic other, more serious inflammatory conditions. Knowledge of its findings on CT would help the radiologist make the diagnosis and allow a more conservative approach to patient care.

  4. Diffuse Infiltrative Splenic Lymphoma: Diagnostic Efficacy of Arterial-Phase CT

    PubMed Central

    Lee, Jeong Eun; Shin, Kyung Sook; Kim, Song Soo; You, Sun Kyoung; Park, Jae Woo; Shin, Hye Soo; Yoon, Yeo Chang

    2016-01-01

    Objective To evaluate the diagnostic performance of obliteration of normal heterogeneous enhancement of the spleen (ONHES) on arterial phase (AP) computed tomography (CT) images in diffuse infiltrative splenic lymphoma (DISL). Materials and Methods One hundred and thirty-six patients with lymphoma who had undergone two-phase (arterial and portal venous) abdominal CT were included in this study. We retrospectively evaluated the diagnostic performance of ONHES on AP CT in diagnosing DISL. Two observers evaluated ONHES on AP CT using the 5-point confidence level and assessed the presence or absence of subjective splenomegaly on axial CT images. Another two observers measured the splenic index as proposed by objective CT criteria. Statistical analysis included interobserver agreement and diagnostic performance of CT findings. Results Eleven of the 136 patients with lymphoma had DISL. The area under the receiver operating characteristic curve of ONHES (0.948 for observer 1 and 0.922 for observer 2) was superior to that of the splenic index (0.872 for observer 3 and 0.877 for observer 4), but the difference was not statistically significant (p > 0.05). The diagnostic performance of ONHES in conjunction with subjective splenomegaly showed higher diagnostic performance, as compared with subjective splenomegaly alone (accuracy: 100% and 85.3% for observer 1, 98.5% and 87.5% for observer 2; positive predictive value: 100% and 35.5% for observer 1, 90.9% and 39.3% for observer 2, respectively). Conclusion Obliteration of normal heterogeneous enhancement of the spleen in conjunction with subjective splenomegaly can improve the diagnostic performance for DISL. Our results suggest that ONHES on AP CT images could be useful as an adjunctive diagnostic indicator of DISL in patients with lymphoma. PMID:27587962

  5. Implementation and characterization of a 320-slice volumetric CT scanner for simulation in radiation oncology

    SciTech Connect

    Coolens, C.; Breen, S.; Purdie, T. G.; Owrangi, A.; Publicover, J.; Bartolac, S.; Jaffray, D. A.

    2009-11-15

    Purpose: Effective target definition and broad employment of treatment response assessment with dynamic contrast-enhanced CT in radiation oncology requires increased speed and coverage for use within a single bolus injection. To this end, a novel volumetric CT scanner (Aquilion One, Toshiba, Tochigi Pref., Japan) has been installed at the Princess Margaret Hospital for implementation into routine CT simulation. This technology offers great advantages for anatomical and functional imaging in both scan speed and coverage. The aim of this work is to investigate the system's imaging performance and quality as well as CT quantification accuracy which is important for radiotherapy dose calculations. Methods: The 320-slice CT scanner uses a 160 mm wide-area (2D) solid-state detector design which provides the possibility to acquire a volumetric axial length of 160 mm without moving the CT couch. This is referred to as ''volume'' and can be scanned with a rotation speed of 0.35-3 s. The scanner can also be used as a 64-slice CT scanner and perform conventional (axial) and helical acquisitions with collimation ranges of 1-32 and 16-32 mm, respectively. Commissioning was performed according to AAPM Reports TG 66 and 39 for both helical and volumetric imaging. Defrise and other cone-beam image analysis tests were performed. Results: Overall, the imaging spatial resolution and geometric efficiency (GE) were found to be very good (>10 lp/mm, <1 mm spatial integrity and GE{sub 160mm}=85%) and within the AAPM guidelines as well as IEC recommendations. Although there is evidence of some cone-beam artifacts when scanning the Defrise phantom, image quality was found to be good and sufficient for treatment planning (soft tissue noise <10 HU). Measurements of CT number stability and contrast-to-noise values across the volume indicate clinically acceptable scan accuracy even at the field edge. Conclusions: Initial experience with this exciting new technology confirms its accuracy for

  6. Comparisons between co-axial and bi-axial optical systems for time-of-flight based laser scanners

    NASA Astrophysics Data System (ADS)

    Jang, Junhwan; Hwang, Sungui; Won, Bumsik; Park, Kyihwan

    2015-07-01

    In time-of-flight based laser scanners, measurable distance and accuracy are the most important parameters to determine performances. The optical system of the laser scanner should be optimally designed since a high intensity of measured signal increases the measurable distance and accuracy. Therefore, it is important to understand how the optical component layout affects the laser scanner performances. Optical component design for co-axial and bi-axial mechanisms are considered in the paper.

  7. Investigation of the failure behaviour of vertebral trabecular architectures under uni-axial compression and wedge action loading conditions.

    PubMed

    McDonnell, P; Harrison, N; McHugh, P E

    2010-07-01

    Vertebral wedge fractures are associated with combined compression and flexure loading and are the most common fracture type for human vertebrae. In this study, rapid prototype (RP) biomodels of human vertebral trabecular bone were mechanically tested under uni-axial compression loading and also under wedge action loading (combination of compression and flexure loading) to investigate the mode of failure and the ultimate loads that could be sustained under these different loading conditions. Two types of trabecular bone models were manufactured and tested: baseline models which were directly derived from microCT scans of human thoracic vertebrae, and osteoporotic models which were generated from the baseline models using a custom-developed bone loss algorithm. The ultimate load for each model under compression and wedge action loading was determined and a video was recorded of each test so that failure mechanisms could be evaluated. The results of the RP model mechanical tests showed that the ultimate loads that could be supported by vertebral trabecular architectures under wedge action loading were less than those that could be supported under uni-axial compression loading by up to 26%. Also, the percentage reduction in strength from the baseline value due to osteoporotic bone loss was slightly less for the wedge action loading compared to uni-axial compression loading. Analysis of the videos for each test revealed that failure occurred in localised regions of the trabecular structure due to bending and buckling of thin vertical struts. These results suggest that vertebral trabecular bone is more susceptible to failure from wedge action loading compared to uni-axial compression loading, although this effect is not exacerbated by osteoporotic bone loss.

  8. Multivariate Analysis of Factors Associated With Axial Symptoms in Unilateral Expansive Open-Door Cervical Laminoplasty With Miniplate Fixation.

    PubMed

    Chen, Hua; Liu, Hao; Deng, Yuxiao; Gong, Quan; Li, Tao; Song, Yueming

    2016-01-01

    Retrospective case-control study.Unilateral expansive open-door cervical laminoplasty with miniplate fixation is an efficient and increasing popular surgery for multilevel cervical spondylotic myelopathy. Axial symptoms are the most frequent complaints after cervical laminoplasty. But the mechanisms have not been fully clarified yet.The objective of this study is to compare the clinical and radiologic data between patients with or without axial symptoms and to investigate the factors associated with axial symptoms by multivariate analysis in cervical laminoplasty with miniplate fixation.A total of 129 patients who underwent cervical laminoplasty with miniplate fixation were comprised from August 2009 to March 2014. Patients were grouped according to whether they suffered from postoperative axial symptoms (PA) or not (NA). The clinical data including gender, age, duration of symptoms, diagnosis type, medical comorbidity, operative level, blood loss, operative time, pre- and post-Japanese Orthopedic Association (JOA) score, JOA recovery rates, and other complications were recorded. The radiologic data including cervical canal diameter, C2-7 Cobb angle, cervical range of motion (ROM), cross-sectional area, open angle, hinge union, and facet joint destroyed would be measured according to X-ray plain and CT scan images. The univariate analysis and multivariate logistic regression analysis were performed.There were 39 patients in PA group and 90 patients in NA group. Both groups gained significant JOA improvement postoperatively (P < 0.05). The preoperative neck pain (P = 0.048), negative change of cervical ROM (P = 0.018), and facet joints destroyed (P = 0.022) were significant different between the 2 groups. There were no significant differences for other clinical and radiography parameters between the groups (P > 0.05). The multivariate analysis showed that the negative change of cervical ROM (OR = 1.062, P = 0.047) and facet joints

  9. Patient-specific radiation dose and cancer risk estimation in CT: Part I. Development and validation of a Monte Carlo program

    SciTech Connect

    Li Xiang; Samei, Ehsan; Segars, W. Paul; Sturgeon, Gregory M.; Colsher, James G.; Toncheva, Greta; Yoshizumi, Terry T.; Frush, Donald P.

    2011-01-15

    Purpose: Radiation-dose awareness and optimization in CT can greatly benefit from a dose-reporting system that provides dose and risk estimates specific to each patient and each CT examination. As the first step toward patient-specific dose and risk estimation, this article aimed to develop a method for accurately assessing radiation dose from CT examinations. Methods: A Monte Carlo program was developed to model a CT system (LightSpeed VCT, GE Healthcare). The geometry of the system, the energy spectra of the x-ray source, the three-dimensional geometry of the bowtie filters, and the trajectories of source motions during axial and helical scans were explicitly modeled. To validate the accuracy of the program, a cylindrical phantom was built to enable dose measurements at seven different radial distances from its central axis. Simulated radial dose distributions in the cylindrical phantom were validated against ion chamber measurements for single axial scans at all combinations of tube potential and bowtie filter settings. The accuracy of the program was further validated using two anthropomorphic phantoms (a pediatric one-year-old phantom and an adult female phantom). Computer models of the two phantoms were created based on their CT data and were voxelized for input into the Monte Carlo program. Simulated dose at various organ locations was compared against measurements made with thermoluminescent dosimetry chips for both single axial and helical scans. Results: For the cylindrical phantom, simulations differed from measurements by -4.8% to 2.2%. For the two anthropomorphic phantoms, the discrepancies between simulations and measurements ranged between (-8.1%, 8.1%) and (-17.2%, 13.0%) for the single axial scans and the helical scans, respectively. Conclusions: The authors developed an accurate Monte Carlo program for assessing radiation dose from CT examinations. When combined with computer models of actual patients, the program can provide accurate dose

  10. Cardiac cone-beam CT

    SciTech Connect

    Manzke, Robert . E-mail: robert.manzke@philips.com

    2005-10-15

    This doctoral thesis addresses imaging of the heart with retrospectively gated helical cone-beam computed tomography (CT). A thorough review of the CT reconstruction literature is presented in combination with a historic overview of cardiac CT imaging and a brief introduction to other cardiac imaging modalities. The thesis includes a comprehensive chapter about the theory of CT reconstruction, familiarizing the reader with the problem of cone-beam reconstruction. The anatomic and dynamic properties of the heart are outlined and techniques to derive the gating information are reviewed. With the extended cardiac reconstruction (ECR) framework, a new approach is presented for the heart-rate-adaptive gated helical cardiac cone-beam CT reconstruction. Reconstruction assessment criteria such as the temporal resolution, the homogeneity in terms of the cardiac phase, and the smoothness at cycle-to-cycle transitions are developed. Several reconstruction optimization approaches are described: An approach for the heart-rate-adaptive optimization of the temporal resolution is presented. Streak artifacts at cycle-to-cycle transitions can be minimized by using an improved cardiac weighting scheme. The optimal quiescent cardiac phase for the reconstruction can be determined automatically with the motion map technique. Results for all optimization procedures applied to ECR are presented and discussed based on patient and phantom data. The ECR algorithm is analyzed for larger detector arrays of future cone-beam systems throughout an extensive simulation study based on a four-dimensional cardiac CT phantom. The results of the scientific work are summarized and an outlook proposing future directions is given. The presented thesis is available for public download at www.cardiac-ct.net.

  11. National Survey of Radiation Dose and Image Quality in Adult CT Head Scans in Taiwan

    PubMed Central

    Lin, Chung-Jung; Mok, Greta S. P.; Tsai, Mang-Fen; Tsai, Wei-Ta; Yang, Bang-Hung; Tu, Chun-Yuan; Wu, Tung-Hsin

    2015-01-01

    Introduction The purpose of the present study was to evaluate the influence of different variables on radiation dose and image quality based on a national database. Materials and Methods Taiwan’s Ministry of Health and Welfare requested all radiology departments to complete a questionnaire for each of their CT scanners. Information gathered included all scanning parameters for CT head scans. For the present analysis, CT machines were divided into three subgroups: single slice CT (Group A); multi-detector CT (MDCT) with 2-64 slices (Group B); and MDCT with more than 64 slices (Group C). Correlations between computed tomography dose index (CTDI) and signal-to-noise ratio (SNR) with cumulated tube rotation number (CTW(n)) and cumulated tube rotation time (CTW(s)), and sub group analyses of CTDI and SNR across the three groups were performed. Results CTDI values demonstrated a weak correlation (r = 0.33) with CTW(n) in Group A. SNR values demonstrated a weak negative correlation (r = -0.46) with CTW(n) in Group C. MDCT with higher slice numbers used more tube potential resulting in higher effective doses. There were both significantly lower CTDI and SNR values in helical mode than in axial mode in Group B, but not Group C. Conclusion CTW(n) and CTW(s) did not influence radiation output. Helical mode is more often used in MDCT and results in both lower CTDI and SNR compared to axial mode in MDCT with less than 64 slices. PMID:26125549

  12. A method for smoothing segmented lung boundary in chest CT images

    NASA Astrophysics Data System (ADS)

    Yim, Yeny; Hong, Helen

    2007-03-01

    To segment low density lung regions in chest CT images, most of methods use the difference in gray-level value of pixels. However, radiodense pulmonary vessels and pleural nodules that contact with the surrounding anatomy are often excluded from the segmentation result. To smooth lung boundary segmented by gray-level processing in chest CT images, we propose a new method using scan line search. Our method consists of three main steps. First, lung boundary is extracted by our automatic segmentation method. Second, segmented lung contour is smoothed in each axial CT slice. We propose a scan line search to track the points on lung contour and find rapidly changing curvature efficiently. Finally, to provide consistent appearance between lung contours in adjacent axial slices, 2D closing in coronal plane is applied within pre-defined subvolume. Our method has been applied for performance evaluation with the aspects of visual inspection, accuracy and processing time. The results of our method show that the smoothness of lung contour was considerably increased by compensating for pulmonary vessels and pleural nodules.

  13. Axially staggered seed-blanket reactor fuel module construction

    DOEpatents

    Cowell, Gary K.; DiGuiseppe, Carl P.

    1985-01-01

    A heterogeneous nuclear reactor of the seed-blanket type is provided wher the fissile (seed) and fertile (blanket) nuclear fuels are segregated axially within each fuel element such that fissile and fertile regions occur in an alternating pattern along the length of the fuel element. Further, different axial stacking patterns are used for the fuel elements of at least two module types such that when modules of different types are positioned adjacent to one another, the fertile regions of the modules are offset or staggered. Thus, when a module of one type is surrounded by modules of the second type the fertile regions thereof will be surrounded on all sides by fissile material. This provides enhanced neutron communication both radially and axially, thereby resulting in greater power oscillation stability than other axial arrangements. The arrangements of the fissile and fertile regions in an alternating axial manner minimizes the radial power peaking factors and provides a more optional thermal-hydraulic design than is afforded by radial arrangements.

  14. An Axial-Vector Photon in a Mirror World

    NASA Astrophysics Data System (ADS)

    Sharafiddinov, Rasulkhozha S.

    2016-03-01

    The unity of symmetry laws emphasizes, in the case of a mirror CP-even Dirac Lagrangian, the ideas of the left- and right-handed axial-vector photons referring to long- and short-lived bosons of true neutrality, respectively. Such a difference in lifetimes expresses the unidenticality of masses, energies and momenta of axial-vector photons of the different components. They define the unified field theory equation of C-odd particles with an integral spin. Together with a new equation of a theory of truly neutral particles with the half-integral spin, the latter reflects the availability in their nature of the second type of the local axial-vector gauge transformation responsible for origination in the Lagrangian of C-oddity of an interaction Newton component giving an axial-vector mass to all the interacting particles and fields. The mirror axial-vector mass, energy and momentum operators constitute a CP-invariant equation of quantum mechanics, confirming that each of them can individually influence on matter field. Thereby, findings suggest at the level of the mass-charge structure of gauge invariance a new equation for the C-noninvariant Lagrangian.

  15. Multi-axial mechanical properties of human trabecular bone.

    PubMed

    Rincón-Kohli, Liliana; Zysset, Philippe K

    2009-06-01

    In the context of osteoporosis, evaluation of bone fracture risk and improved design of epiphyseal bone implants rely on accurate knowledge of the mechanical properties of trabecular bone. A multi-axial loading chamber was designed, built and applied to explore the compressive multi-axial yield and strength properties of human trabecular bone from different anatomical locations. A thorough experimental protocol was elaborated for extraction of cylindrical bone samples, assessment of their morphology by micro-computed tomography and application of different mechanical tests: torsion, uni-axial traction, uni-axial compression and multi-axial compression. A total of 128 bone samples were processed through the protocol and subjected to one of the mechanical tests up to yield and failure. The elastic data were analyzed using a tensorial fabric-elasticity relationship, while the yield and strength data were analyzed with fabric-based, conewise generalized Hill criteria. For each loading mode and more importantly for the combined results, strong relationships were demonstrated between volume fraction, fabric and the elastic, yield and strength properties of human trabecular bone. Despite the reviewed limitations, the obtained results will help improve the simulation of the damage behavior of human bones and bone-implant systems using the finite element method.

  16. Light Weakly Coupled Axial Forces: Models, Constraints, and Projections

    SciTech Connect

    Kahn, Yonatan; Krnjaic, Gordan; Mishra-Sharma, Siddharth; Tait, Tim P.

    2016-09-28

    We investigate the landscape of constraints on MeV-GeV scale, hidden U(1) forces with nonzero axial-vector couplings to Standard Model fermions. While the purely vector-coupled dark photon, which may arise from kinetic mixing, is a well-motivated scenario, several MeV-scale anomalies motivate a theory with axial couplings which can be UV-completed consistent with Standard Model gauge invariance. Moreover, existing constraints on dark photons depend on products of various combinations of axial and vector couplings, making it difficult to isolate the effects of axial couplings for particular flavors of SM fermions. We present a representative renormalizable, UV-complete model of a dark photon with adjustable axial and vector couplings, discuss its general features, and show how some UV constraints may be relaxed in a model with nonrenormalizable Yukawa couplings at the expense of fine-tuning. We survey the existing parameter space and the projected reach of planned experiments, briefly commenting on the relevance of the allowed parameter space to low-energy anomalies in pi^0 and 8-Be* decay.

  17. Development and Testing of an Axial Halbach Magnetic Bearing

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.; Gallo, Christopher A.; Thompson, William K.

    2006-01-01

    The NASA Glenn Research Center has developed and tested a revolutionary Axial Halbach Magnetic Bearing. The objective of this work is to develop a viable non-contact magnetic thrust bearing utilizing Halbach arrays for all-electric flight, and many other applications. This concept will help to reduce harmful emissions, reduce the Nation s dependence on fossil fuels and mitigate many of the concerns and limitations encountered in conventional axial bearings such as bearing wear, leaks, seals and friction loss. The Axial Halbach Magnetic Bearing is inherently stable and requires no active feedback control system or superconductivity as required in many magnetic bearing designs. The Axial Halbach Magnetic Bearing is useful for very high speed applications including turbines, instrumentation, medical systems, computer memory systems, and space power systems such as flywheels. Magnetic fields suspend and support a rotor assembly within a stator. Advanced technologies developed for particle accelerators, and currently under development for maglev trains and rocket launchers, served as the basis for this application. Experimental hardware was successfully designed and developed to validate the basic principles and analyses. The report concludes that the implementation of Axial Halbach Magnetic Bearings can provide significant improvements in rotational system performance and reliability.

  18. Trunk axial rotation in baseball pitching and batting.

    PubMed

    Fleisig, Glenn S; Hsu, Wellington K; Fortenbaugh, Dave; Cordover, Andrew; Press, Joel M

    2013-11-01

    The purpose of this study was to quantify trunk axial rotation and angular acceleration in pitching and batting of elite baseball players. Healthy professional baseball pitchers (n = 40) and batters (n = 40) were studied. Reflective markers attached to each athlete were tracked at 240 Hz with an eight-camera automated digitizing system. Trunk axial rotation was computed as the angle between the pelvis and the upper trunk in the transverse plane. Trunk angular acceleration was the second derivative of axial rotation. Maximum trunk axial rotation (55 +/- 6 degrees) and angular acceleration (11,600 +/- 3,100 degrees/s2) in pitching occurred before ball release, approximately at the instant the front foot landed. Maximum trunk axial rotation (46 +/- 9 degrees) and angular acceleration (7,200 +/- 2,800 degrees/s2) in batting occurred in the follow-through after ball contact. Thus, the most demanding instant for the trunk and spine was near front foot contact for pitching and after ball contact for batting.

  19. Optical axial scanning in confocal microscopy using an electrically tunable lens.

    PubMed

    Jabbour, Joey M; Malik, Bilal H; Olsovsky, Cory; Cuenca, Rodrigo; Cheng, Shuna; Jo, Javier A; Cheng, Yi-Shing Lisa; Wright, John M; Maitland, Kristen C

    2014-02-01

    This paper presents the use and characterization of an electrically focus tunable lens to perform axial scanning in a confocal microscope. Lateral and axial resolution are characterized over a >250 µm axial scan range. Confocal microscopy using optical axial scanning is demonstrated in epithelial tissue and compared to traditional stage scanning. By enabling rapid axial scanning, minimizing motion artifacts, and reducing mechanical complexity, this technique has potential to enhance in vivo three-dimensional imaging in confocal endomicroscopy.

  20. Malignant external otitis: CT evaluation

    SciTech Connect

    Curtin, H.D.; Wolfe, P.; May, M.

    1982-11-01

    Malignant external otitis is an aggressive infection caused by Pseudomonas aeruginosa that most often occurs in elderly diabetics. Malignant external otitis often spreads inferiorly from the external canal to involve the subtemporal area and progresses medially towards the petrous apex leading to multiple cranial nerve palsies. The computed tomographic (CT) findings in malignant external otitis include obliteration of the normal fat planes in the subtemporal area as well as patchy destruction of the bony cortex of the mastoid. The point of exit of the various cranial nerves can be identified on CT scans, and the extent of the inflammatory mass correlates well with the clinical findings. Four cases of malignant external otitis are presented. In each case CT provided a good demonstration of involvement of the soft tissues at the base of the skull.

  1. Dosimetric and image quality assessment of different acquisition protocols of a novel 64-slice CT scanner

    NASA Astrophysics Data System (ADS)

    Vite, Cristina; Mangini, Monica; Strocchi, Sabina; Novario, Raffaele; Tanzi, Fabio; Carrafiello, Gianpaolo; Conte, Leopoldo; Fugazzola, Carlo

    2006-03-01

    Dose and image quality assessment in computed tomography (CT) are almost affected by the vast variety of CT scanners (axial CT, spiral CT, low-multislice CT (2-16), high-multislice CT (32-64)) and imaging protocols in use. Very poor information is at the moment available on 64 slices CT scanners. Aim of this work is to assess image quality related to patient dose indexes and to investigate the achievable dose reduction for a commercially available 64 slices CT scanner. CT dose indexes (weighted computed tomography dose index, CTDI w and Dose Length Product, DLP) were measured with a standard CT phantom for the main protocols in use (head, chest, abdomen and pelvis) and compared with the values displayed by the scanner itself. The differences were always below 7%. All the indexes were below the Diagnostic Reference Levels defined by the European Council Directive 97/42. Effective doses were measured for each protocol with thermoluminescent dosimeters inserted in an anthropomorphic Alderson Rando phantom and compared with the same values computed by the ImPACT CT Patient Dosimetry Calculator software code and corrected by a factor taking in account the number of slices (from 16 to 64). The differences were always below 25%. The effective doses range from 1.5 mSv (head) to 21.8 mSv (abdomen). The dose reduction system of the scanner was assessed comparing the effective dose measured for a standard phantom-man (a cylinder phantom, 32 cm in diameter) to the mean dose evaluated on 46 patients. The standard phantom was considered as no dose reduction reference. The dose reduction factor range from 16% to 78% (mean of 46%) for all protocols, from 29% to 78% (mean of 55%) for chest protocol, from 16% to 76% (mean of 42%) for abdomen protocol. The possibility of a further dose reduction was investigated measuring image quality (spatial resolution, contrast and noise) as a function of CTDI w. This curve shows a quite flat trend decreasing the dose approximately to 90% and a

  2. Recent technologic advances in multi-detector row cardiac CT.

    PubMed

    Halliburton, Sandra Simon

    2009-11-01

    Recent technical advances in multi-detector row CT have resulted in lower radiation dose, improved temporal and spatial resolution, decreased scan time, and improved tissue differentiation. Lower radiation doses have resulted from the use of pre-patient z collimators, the availability of thin-slice axial data acquisition, the increased efficiency of ECG-based tube current modulation, and the implementation of iterative reconstruction algorithms. Faster gantry rotation and the simultaneous use of two x-ray sources have led to improvements in temporal resolution, and gains in spatial resolution have been achieved through application of the flying x-ray focal-spot technique in the z-direction. Shorter scan times have resulted from the design of detector arrays with increasing numbers of detector rows and through the simultaneous use of two x-ray sources to allow higher helical pitch. Some improvement in tissue differentiation has been achieved with dual energy CT. This article discusses these recent technical advances in detail.

  3. Bistability between equatorial and axial dipoles during magnetic field reversals.

    PubMed

    Gissinger, Christophe; Petitdemange, Ludovic; Schrinner, Martin; Dormy, Emmanuel

    2012-06-08

    Numerical simulations of the geodynamo in the presence of heterogeneous heating are presented. We study the dynamics and the structure of the magnetic field when the equatorial symmetry of the flow is broken. If the symmetry breaking is sufficiently strong, the m=0 axial dipolar field is replaced by a hemispherical magnetic field, dominated by an oscillating m=1 magnetic field. Moreover, for moderate symmetry breaking, a bistability between the axial and the equatorial dipole is observed. In this bistable regime, the axial magnetic field exhibits chaotic switches of its polarity, involving the equatorial dipole during the transition period. This new scenario for magnetic field reversals is discussed within the framework of Earth's dynamo.

  4. Compressive failure of fiber composites under multi-axial loading

    NASA Astrophysics Data System (ADS)

    Basu, Shiladitya; Waas, Anthony M.; Ambur, Damodar R.

    2006-03-01

    This paper examines the compressive strength of a fiber reinforced lamina under multi-axial stress states. An equilibrium analysis is carried out in which a kinked band of rotated fibers, described by two angles, is sandwiched between two regions in which the fibers are nominally straight. Proportional multi-axial stress states are examined. The analysis includes the possibility of bifurcation from the current equilibrium state. The compressive strength of the lamina is contingent upon either attaining a load maximum in the equilibrium response or satisfaction of a bifurcation condition, whichever occurs first. The results show that for uniaxial loading a non-zero kink band angle β produces the minimum limit load. For multi-axial loading, different proportional loading paths show regimes of bifurcation dominated and limit load dominated behavior. The present results are able to capture the beneficial effect of transverse compression in raising the composite compressive strength as observed in experiments.

  5. Compressive Failure of Fiber Composites under Multi-Axial Loading

    NASA Technical Reports Server (NTRS)

    Basu, Shiladitya; Waas, Anthony M.; Ambur, Damodar R.

    2006-01-01

    This paper examines the compressive strength of a fiber reinforced lamina under multi-axial stress states. An equilibrium analysis is carried out in which a kinked band of rotated fibers, described by two angles, is sandwiched between two regions in which the fibers are nominally straight. Proportional multi-axial stress states are examined. The analysis includes the possibility of bifurcation from the current equilibrium state. The compressive strength of the lamina is contingent upon either attaining a load maximum in the equilibrium response or satisfaction of a bifurcation condition, whichever occurs first. The results show that for uniaxial loading a non-zero kink band angle beta produces the minimum limit load. For multi-axial loading, different proportional loading paths show regimes of bifurcation dominated and limit load dominated behavior. The present results are able to capture the beneficial effect of transverse compression in raising the composite compressive strength as observed in experiments.

  6. Ball Screw Actuator Including an Axial Soft Stop

    NASA Technical Reports Server (NTRS)

    Wingett, Paul T. (Inventor); Forrest, Steven Talbert (Inventor); Abel, Steve (Inventor); Woessner, George (Inventor); Hanlon, Casey (Inventor)

    2016-01-01

    An actuator includes an actuator housing, a ball screw, and an axial soft stop assembly. The ball screw extends through the actuator housing and has a first end and a second end. The ball screw is coupled to receive a drive force and is configured, upon receipt of the drive force, to selectively move in a retract direction and an extend direction. The axial soft stop assembly is disposed within the actuator housing. The axial soft stop assembly is configured to be selectively engaged by the ball screw and, upon being engaged thereby, to translate, with compliance, a predetermined distance in the extend direction, and to prevent further movement of the ball screw upon translating the predetermined distance.

  7. Elastic Buckling of Laminated Plates Under Varying Axial Stresses

    NASA Technical Reports Server (NTRS)

    Badir, A.; Hu, H.

    1998-01-01

    The elastic buckling load of simply supported rectangular composite plates subjected to a second degree parabolic variation of axial stresses in the longitudinal direction is calculated using analytical methods. The variation of axial stresses is equilibrated by nonuniform shear stresses along the plate edges and transverse normal stresses. Numerical results are reported for three different cases: (1) orthotropic plates, (2) symmetrically laminated plates with multiple generally orthotropic layers exhibiting coupling between normal moments and twist, and twisting moment and normal curvatures, and (3) unsymmetrically laminated plates. Rayleigh-Ritz method is used to calculate the buckling load. An approximate solution using "reduced bending stiffness" is adopted for unsymmetrically laminated plates. The influence of the aspect ratio is examined, and the results are compared with plates subjected to uniform axial stresses.

  8. Removal of Axial Twist in RHIC Insertion Quadrupole Magnets

    NASA Astrophysics Data System (ADS)

    Cozzolino, J.; Anerella, M.; Jain, A.; Louie, W.; Muratore, P.

    1997-05-01

    The focusing triplets located on either side of the six interaction points of RHIC each consist of three 13cm aperture quadrupoles with magnetic lengths of 1.44m (Q1), 3.40m (Q2), and 2.10m (Q3). The field quality and alignment of these magnets are most critical to the performance of the accelerator. The maximum allowable axial twist of the cold mass, defined as the standard deviation in the quadrupole roll angle, is 0.5 mrad. This requirement has occasionally exceeded the capabilities of the assembly fixturing and the procedures used to complete the axial welding of the shell halves around the cold mass yoke. A corrective shell welding technique has been successfully employed to remove excessive axial twist of the 13cm quadrupoles. This ``custom straightening" method will be described along with the before and after mechanical inspection data. The magnetic results which confirm the untwisting procedure shall also be discussed.

  9. Three-Dimensional Photon Counting Imaging with Axially Distributed Sensing.

    PubMed

    Cho, Myungjin; Javidi, Bahram

    2016-07-28

    In this paper, we review three-dimensional (3D) photon counting imaging with axially distributed sensing. Under severely photon-starved conditions, we have proposed various imaging and algorithmic approaches to reconstruct a scene in 3D, which are not possible by using conventional imaging system due to lack of sufficient number of photons. In this paper, we present an overview of optical sensing and imaging system along with dedicated algorithms for reconstructing 3D scenes by photon counting axially distributed sensing, which may be implemented by moving a single image sensor along its optical axis. To visualize the 3D image, statistical estimation methods and computational reconstruction of axially distributed sensing is applied.

  10. Investigation of Aluminum-Copper Tube Hydroforming with Axial Feeding

    NASA Astrophysics Data System (ADS)

    Parto D., M.; Seyedkashi, S. M. H.; Liaghat, Gh.; Naeini, H. Moslemi; Panahizadeh R., V.

    2011-01-01

    Hydroforming of a two-layered Aluminum-Copper tube is investigated numerically and experimentally. Pressure is applied through a nonlinear path along with symmetrical axial feeding. ABAQUS/Explicit commercial code is used for finite element simulation of the process. ASTM C11000 Copper alloy is used as inner layer and ASTM AA1050A Aluminum alloy is used as outer layer. The simulation results show that the part can be successfully formed under internal pressure of 40 MPa with 8 mm axial displacement. Stress distributions on both inner and outer tubes are compared and maximum thinning on their wall is also discussed. Different friction conditions are applied on the process using different coefficients of friction and their effects are investigated on thinning percentage of inner and outer tubes and also on axial feeding. It is observed that finite element results are in good agreement with experimental results.

  11. Axial asymmetry in holographic and incoherent correlation imaging

    NASA Astrophysics Data System (ADS)

    Běhal, Jaromír.; Bouchal, Petr; Schovánek, Petr; Fordey, Tomáš; Bouchal, Zdeněk

    2016-12-01

    In optical lens imaging, the main attention has traditionally been paid to the lateral resolution roughly estimated by a two-dimensional point spread function (PSF) describing sharp image of a point object. In three-dimensional (3D) imaging and methods based on depth information, an axial profile of the PSF becomes of particular importance. In studies on the 3D PSF, the axial image asymmetry and shift of the intensity maximum out of the focal plane were revealed for optical systems characterized by low Fresnel numbers. In this paper, the 3D PSF is examined in terms of digital imaging, where a point object is recorded optically and its image reconstructed numerically. The analysis includes methods of digital holography, in which the axial image asymmetry is examined in relation to different geometries of coherent recording waves. Attention is also devoted to the Fresnel incoherent correlation imaging that enables recording of 3D objects in spatially incoherent light.

  12. [Gallstone ileus. Abdominal CT usefulness].

    PubMed

    Sukkarieh, F; Brasseur, P; Bissen, L

    2004-06-01

    The authors report the case of a 93-year old woman referred to the emergency department and presenting with an intestinal obstruction. Abdominal CT reveals a biliary ileus caused by the migration and the impaction of a 3 cm gallstone in the small bowel. Surgical treatment by enterolithotomy was successful. In over 90% of cases, gallstone ileus is a complication of cholelithiasis and accounts for 25% of intestinal obstruction in patients over 65 years. To reduce morbidity and mortality, early diagnosis and prompt treatment are essential. Abdominal CT-scan is the gold standard technique.

  13. Granulocytic sarcoma (chloroma): CT manifestations

    SciTech Connect

    Pomeranz, S.J.; Hawkins, H.H.; Towbin, R.; Lisberg, W.N.; Clark, R.A.

    1985-04-01

    Nests of granulocytic tumor cells in patients who have myelogeneous leukemia are termed chloromas. Eight cases of chloroma seen on CT were reviewed. Lymph nodes, subcutaneous tissues, peritoneum, pleural space, pelvis, and portal hepatis were involved. The extracranial appearance of chloroma on CT is that of small, nonenhancing, nodular densities that resemble lymphoma. Cranial involvement is characteristically in the orbit. The central nervous system appearance is variable, however, and high attenuation masses may occur that mimic lymphoma, hematoma, and metastatic neuroblastoma. The recognition of these lesions is important, since radiation, not chemotherapy, is often the preferred treatment for localized chloroma.

  14. Ontological analysis of SNOMED CT

    PubMed Central

    Héja, Gergely; Surján, György; Varga, Péter

    2008-01-01

    Background SNOMED CT is the most comprehensive medical terminology. However, its use for intelligent services based on formal reasoning is questionable. Methods The analysis of the structure of SNOMED CT is based on the formal top-level ontology DOLCE. Results The analysis revealed several ontological and knowledge-engineering errors, the most important are errors in the hierarchy (mostly from an ontological point of view, but also regarding medical aspects) and the mixing of subsumption relations with other types (mostly 'part of'). Conclusion The found errors impede formal reasoning. The paper presents a possible way to correct these problems. PMID:19007445

  15. Investigation of rat bone fracture healing using pulsed 1.5 MHz, 30 mW/cm(2) burst ultrasound--axial distance dependency.

    PubMed

    Fung, Chak-Hei; Cheung, Wing-Hoi; Pounder, Neill M; de Ana, F Javier; Harrison, Andrew; Leung, Kwok-Sui

    2014-03-01

    This study investigated the effect of LIPUS on fracture healing when fractures were exposed to ultrasound at three axial distances: z=0 mm, 60 mm, and 130 mm. We applied LIPUS to rat fracture at these three axial distances mimicking the exposure condition of human fractures at different depths under the soft tissue. Measurement of LIPUS shows pressure variations in near field (nearby transducer); uniform profile was found beyond it (far field). We asked whether different positions of the fracture within the ultrasound field cause inconsistent biological effect during the healing process. Closed femoral fractured Sprague-Dawley rats were randomized into control, near-field (0mm), mid-near field (60 mm) or far-field (130 mm) groups. Daily LIPUS treatment (plane, but apodized source, see details in the text; 2.2 cm in diameter; 1.5 MHz sine waves repeating at 1 kHz PRF; spatial average temporal average intensity, ISATA=30 mW/cm(2)) was given to fracture site at the three axial distances. Weekly radiographs and endpoint microCT, histomorphometry, and mechanical tests were performed. The results showed that the 130 mm group had the highest tissue mineral density; and significantly higher mechanical properties than control at week 4. The 60 mm and 0 mm groups had significantly higher (i.e. p<0.05) woven bone percentage than control group in radiological, microCT and histomorphometry measurements. In general, LIPUS at far field augmented callus mineralization and mechanical properties; while near field and mid-near field enhanced woven bone formation. Our results indicated the therapeutic effect of LIPUS is dependent on the axial distance of the ultrasound beam. Therefore, the depth of fracture under the soft tissue affects the biological effect of LIPUS. Clinicians have to be aware of the fracture depth when LIPUS is applied transcutaneously.

  16. NASA Low-speed Axial Compressor for Fundamental Research

    NASA Technical Reports Server (NTRS)

    Wasserbauer, Charles A.; Weaver, Harold F.; Senyitko, Richard G.

    1995-01-01

    A low-speed multistage axial compressor built by the NASA Lewis Research Center is described. The purpose of this compressor is to increase the understanding of the complex flow phenomena within multistage axial compressors and to obtain detailed data from a multistage compressor environment for use in developing and verifying models for computational fluid dynamic code assessment. The compressor has extensive pressure instrumentation in both stationary and rotating frames of reference, and has provisions for flow visualization and laser velocimetry. The compressor will accommodate rotational speeds to 1050 rpm and is rated at a pressure ratio of 1.042.

  17. Reflective correctors for the Hubble Space Telescope axial instruments.

    PubMed

    Bottema, M

    1993-04-01

    Reflective correctors to compensate the spherical aberration in the Hubble Space Telescope are placed in front of three of the axial scientific instruments (a camera and two spectrographs) during the first scheduled refurbishment mission. The five correctors required are deployed from a new module that replaces the fourth axial instrument. Each corrector consists of a field mirror and an aspherical, aberration-correcting reimaging mirror. In the camera the angular resolution capability is restored, be it in reduced fields, and in the spectrographs the potential for observations in crowded areas is regained along with effective light collection at the slits.

  18. Electrons Confined with an Axially Symmetric Magnetic Mirror Field

    SciTech Connect

    Higaki, H.; Ito, K.; Kira, K.; Okamoto, H.

    2008-08-08

    Low energy non-neutral electron plasmas were confined with an axially symmetric magnetic mirror field and an electrostatic potential to investigate the basic confinement properties of a simple magnetic mirror trap. As expected the confinement time became longer as a function of the mirror ratio. The axial electrostatic oscillations of a confined electron plasma were also observed. Obtained results suggested an improved scheme to accumulate low energy charged particles with the use of a magnetic mirror field, which would enable the investigation of electron-positron plasmas.

  19. Recent Results on High-Pressure Axial Blowers

    NASA Technical Reports Server (NTRS)

    Eckert, B.

    1947-01-01

    Considerable progress has, in recent times, been attained in the development of the high-pressure axial blower by well-planned research. The efforts are directed toward improving the efficiencies, which are already high for the axial blower, and in particular the delivery pressure heads. For high pressures multistage arrangements are used. Of fundamental importance is the careful design of all structural parts of the blower that are subject to the effects of the flow. In the present report, several recent results and experiences are reported, which are based on results of German engine research.

  20. Reflective correctors for the Hubble Space Telescope axial instruments

    NASA Technical Reports Server (NTRS)

    Bottema, Murk

    1993-01-01

    Reflective correctors to compensate the spherical aberration in the Hubble Space Telescope are placed in front of three of the axial scientific instruments (a camera and two spectrographs) during the first scheduled refurbishment mission. The five correctors required are deployed from a new module that replaces the fourth axial instrument. Each corrector consists of a field mirror and an aspherical, aberration-correcting reimaging mirror. In the camera the angular resolution capability is restored, be it in reduced fields, and in the spectrographs the potential for observations in crowded areas is regained along with effective light collection at the slits.

  1. SSME alternate turbopump (pump section) axial load analysis

    NASA Technical Reports Server (NTRS)

    Crease, G. A.; Rosello, A., Jr.; Fetfatsidis, A. K.

    1989-01-01

    A flow balancing computer program constructed to calculate the axial loads on the Space Shuttle Main Engine (SSME) alternate turbopumps (ATs) pump sections are described. The loads are used in turn to determine load balancing piston design requirements. The application of the program to the inlet section, inducer/impeller/stage, bearings, seals, labyrinth, damper, piston, face and corner, and stationary/rotating surfaces is indicated. Design analysis results are reported which show that the balancing piston's designs are adequate and that performance and life will not be degraded by the turbopump's axial load characteristics.

  2. Miniaturization of a magnetically levitated axial flow blood pump.

    PubMed

    Cheng, Shanbao; Olles, Mark W; Olsen, Don B; Joyce, Lyle D; Day, Steven W

    2010-10-01

    This article introduces a unique miniaturization process of a magnetically levitated axial flow blood pump from a functional prototype to a pump suitable for animal trials. Through COMSOL three-dimensional finite element analysis and experimental verification, the hybrid magnetic bearings of the pump have been miniaturized, the axial spacing between magnetic components has been reduced, and excess material in mechanical components of the pump was reduced. Experimental results show that the pump performance was virtually unchanged and the smaller size resulted in the successful acute pump implantation in calves.

  3. A high-performance axial-field magnetic gear

    NASA Astrophysics Data System (ADS)

    Mezani, S.; Atallah, K.; Howe, D.

    2006-04-01

    The paper describes an axial-field topology of magnetic gear, which is particularly suitable for applications which require a hermetic isolation between the input and output shafts, such as pumps for use in the chemical/pharmaceutical, food, and aerospace industries. It is shown that a torque density in excess of 70 kN m/m3 can be achieved, and that the axial forces, which are exerted on the high-speed and low-speed rotors, are relatively low.

  4. EVOLUTION OF THE AXIAL MAGNETIC FIELD IN SOLAR FILAMENT CHANNELS

    SciTech Connect

    Litvinenko, Yuri E.

    2010-09-01

    Formation of solar filament channels by photospheric magnetic reconnection is considered. A magnetohydrodynamic model for magnetic merging, driven by converging convective motions in the photosphere, is presented. Evolution of the axial magnetic field in a channel is analyzed. An exact time-dependent analytical solution for the field profile in a steady stagnation-point flow is derived. The maximum magnetic field in the channel is determined, and its dependence on the reconnection inflow speed is discussed. The quantitative results show that the maximum axial magnetic field in a forming channel is an indicator of the photospheric reconnection rate, in agreement with recent solar observations and laboratory experiments.

  5. Infrared and terahertz radiation of a crystal at axial channeling

    NASA Astrophysics Data System (ADS)

    Epp, V.; Mitrofanova, T. G.; Zotova, M. A.

    2015-08-01

    Basic properties of radiation of a crystal lattice excited by an axial channeling particle are considered. It is shown that a coherent radiation of atoms occurs if the frequency of oscillations of the channeled particle comes to a resonance with the vibrational mode of the crystal. Spectral and angular distribution of radiation and its polarization are calculated. In case of a relativistic channeled particle, the radiation of atoms is generated into a narrow cone in the direction of a crystallographic axis along which the particle is channeling. The radiation of atoms exited at axial channelling has significant degree of circular polarization.

  6. The axial topographic high at intermediate and fast spreading ridges

    NASA Astrophysics Data System (ADS)

    Carbotte, Suzanne M.; MacDonald, Ken C.

    1994-12-01

    An axial topographic high is commonly observed at both fast spreading ridges and some segments of intermediate spreading ridges. At fast rates the axial high is primarily created by the buoyancy of hot rock and magma beneath the rise. As newly formed crust is transported off axis, little vestige of an axial high is observed on the ridge flanks. In contrast, at intermediate rates, a significant component of the positive topography may be a volcanic construction, preserved on the ridge flanks as abyssal hills, which are slit axial volcanoes. We suggest this difference in the nature of the axial high reflects a lithosphere strong enough to support construction of a volcanic crestal ridge at intermediate spreading rates, but only rarely at fast rates. Relict overlap ridges, found within the discordant zones left by overlapping spreading centers, is one class of ridge-flank topography which appears to have a significant volcanic constructional component even at fast spreading ridges. Unlike topography away from these discontinuities, the relief and shape of overlapping spreading centers is preserved as relict ridge tips are rafted onto the ridge flanks. Reduced magma supply at these discontinuities may give rise to an axial lithosphere strong enough to support volcanic construction of overlap ridges. Low axial lithospheric strength may also account for the lack of normal faults within the innermost 1-2 km of fast, and some intermediate, spreading ridges. With a thin/weak brittle layer at the ridge crest, tensile failure will predominate and few normal faults will form. Depths to the axial magma chamber reflector observed in multi-channel seismic data limit the thickness of the brittel layer on axis to less than 1-2 km for much of the East Pacific Rise (EPR). This depth is comparable to depths over which tensile failure within the oceanic crust will predominate, estimated from the Griffith criteria for fracture initiation (approx. 0.5-1.5 km). As the brittle layer

  7. Classification of CT brain images based on deep learning networks.

    PubMed

    Gao, Xiaohong W; Hui, Rui; Tian, Zengmin

    2017-01-01

    While computerised tomography (CT) may have been the first imaging tool to study human brain, it has not yet been implemented into clinical decision making process for diagnosis of Alzheimer's disease (AD). On the other hand, with the nature of being prevalent, inexpensive and non-invasive, CT does present diagnostic features of AD to a great extent. This study explores the significance and impact on the application of the burgeoning deep learning techniques to the task of classification of CT brain images, in particular utilising convolutional neural network (CNN), aiming at providing supplementary information for the early diagnosis of Alzheimer's disease. Towards this end, three categories of CT images (N = 285) are clustered into three groups, which are AD, lesion (e.g. tumour) and normal ageing. In addition, considering the characteristics of this collection with larger thickness along the direction of depth (z) (~3-5 mm), an advanced CNN architecture is established integrating both 2D and 3D CNN networks. The fusion of the two CNN networks is subsequently coordinated based on the average of Softmax scores obtained from both networks consolidating 2D images along spatial axial directions and 3D segmented blocks respectively. As a result, the classification accuracy rates rendered by this elaborated CNN architecture are 85.2%, 80% and 95.3% for classes of AD, lesion and normal respectively with an average of 87.6%. Additionally, this improved CNN network appears to outperform the others when in comparison with 2D version only of CNN network as well as a number of state of the art hand-crafted approaches. As a result, these approaches deliver accuracy rates in percentage of 86.3, 85.6 ± 1.10, 86.3 ± 1.04, 85.2 ± 1.60, 83.1 ± 0.35 for 2D CNN, 2D SIFT, 2D KAZE, 3D SIFT and 3D KAZE respectively. The two major contributions of the paper constitute a new 3-D approach while applying deep learning technique to extract signature information

  8. PET/CT in radiation oncology

    SciTech Connect

    Pan, Tinsu; Mawlawi, Osama

    2008-11-15

    PET/CT is an effective tool for the diagnosis, staging and restaging of cancer patients. It combines the complementary information of functional PET images and anatomical CT images in one imaging session. Conventional stand-alone PET has been replaced by PET/CT for improved patient comfort, patient throughput, and most importantly the proven clinical outcome of PET/CT over that of PET and that of separate PET and CT. There are over two thousand PET/CT scanners installed worldwide since 2001. Oncology is the main application for PET/CT. Fluorine-18 deoxyglucose is the choice of radiopharmaceutical in PET for imaging the glucose uptake in tissues, correlated with an increased rate of glycolysis in many tumor cells. New molecular targeted agents are being developed to improve the accuracy of targeting different disease states and assessing therapeutic response. Over 50% of cancer patients receive radiation therapy (RT) in the course of their disease treatment. Clinical data have demonstrated that the information provided by PET/CT often changes patient management of the patient and/or modifies the RT plan from conventional CT simulation. The application of PET/CT in RT is growing and will become increasingly important. Continuing improvement of PET/CT instrumentation will also make it easier for radiation oncologists to integrate PET/CT in RT. The purpose of this article is to provide a review of the current PET/CT technology, to project the future development of PET and CT for PET/CT, and to discuss some issues in adopting PET/CT in RT and potential improvements in PET/CT simulation of the thorax in radiation therapy.

  9. Buckling of Beams and Columns under Combined Axial and Horizontal Loading with Various Axial Loading Application Locations

    NASA Astrophysics Data System (ADS)

    Javidinejad, Amir

    2012-12-01

    In this paper the buckling behaviour of an I-beam under combined axial and horizontal side loading is examined. It is to shown that the actual application location of the axial loading governs the buck- ling behaviour of the long I-beam. Theoretical formulation is developed to determine the critical buckling load for such combined loading configura- tion from the elastic static theory. Both, the beam deflection theoretical model and the critical load capacity are derived for this combined loading condition. The Finite Element Analysis (FEA) is utilized to apply the axial load on the beam at various configuration locations and it is shown that this application location determines the buckling behaviour and the critical load of the buckling of the I-beam. Numerical example is given.

  10. Four-Dimensional Magnetic Resonance Imaging Using Axial Body Area as Respiratory Surrogate: Initial Patient Results

    SciTech Connect

    Yang, Juan; Cai, Jing; Wang, Hongjun; Chang, Zheng; Czito, Brian G.; Bashir, Mustafa R.; Yin, Fang-Fang

    2014-03-15

    Purpose: To evaluate the feasibility of a retrospective binning technique for 4-dimensional magnetic resonance imaging (4D-MRI) using body area (BA) as a respiratory surrogate. Methods and Materials: Seven patients with hepatocellular carcinoma (4 of 7) or liver metastases (3 of 7) were enrolled in an institutional review board-approved prospective study. All patients were simulated with both computed tomography (CT) and MRI to acquire 3-dimensinal and 4D images for treatment planning. Multiple-slice multiple-phase cine-MR images were acquired in the axial plane for 4D-MRI reconstruction. Image acquisition time per slice was set to 10-15 seconds. Single-slice 2-dimensinal cine-MR images were also acquired across the center of the tumor in orthogonal planes. Tumor motion trajectories from 4D-MRI, cine-MRI, and 4D-CT were analyzed in the superior–inferior (SI), anterior–posterior (AP), and medial–lateral (ML) directions, respectively. Their correlation coefficients (CC) and differences in tumor motion amplitude were determined. Tumor-to-liver contrast-to-noise ratio (CNR) was measured and compared between 4D-CT, 4D-MRI, and conventional T2-weighted fast spin echo MRI. Results: The means (±standard deviations) of CC comparing 4D-MRI with cine-MRI were 0.97 ± 0.03, 0.97 ± 0.02, and 0.99 ± 0.04 in SI, AP, and ML directions, respectively. The mean differences were 0.61 ± 0.17 mm, 0.32 ± 0.17 mm, and 0.14 ± 0.06 mm in SI, AP, and ML directions, respectively. The means of CC comparing 4D-MRI and 4D-CT were 0.95 ± 0.02, 0.94 ± 0.02, and 0.96 ± 0.02 in SI, AP, and ML directions, respectively. The mean differences were 0.74 ± 0.02 mm, 0.33 ± 0.13 mm, and 0.18 ± 0.07 mm in SI, AP, and ML directions, respectively. The mean tumor-to-tissue CNRs were 2.94 ± 1.51, 19.44 ± 14.63, and 39.47 ± 20.81 in 4D-CT, 4D-MRI, and T2-weighted MRI, respectively. Conclusions: The preliminary evaluation of our 4D-MRI technique results in oncologic patients demonstrates its

  11. Low-dose interpolated average CT for attenuation correction in cardiac PET/CT

    NASA Astrophysics Data System (ADS)

    Wu, Tung-Hsin; Zhang, Geoffrey; Wang, Shyh-Jen; Chen, Chih-Hao; Yang, Bang-Hung; Wu, Nien-Yun; Huang, Tzung-Chi

    2010-07-01

    Because of the advantages in the use of high photon flux and thus the short scan times of CT imaging, the traditional 68Ge scans for positron emission tomography (PET) image attenuation correction have been replaced by CT scans in the modern PET/CT technology. The combination of fast CT scan and slow PET scan often causes image misalignment between the PET and CT images due to respiration motion. Use of the average CT derived from cine CT images is reported to reduce such misalignment. However, the radiation dose to patients is higher with cine CT scans. This study introduces a method that uses breath-hold CT images and their interpolations to generate the average CT for PET image attenuation correction. Breath-hold CT sets are taken at end-inspiration and end-expiration. Deformable image registration is applied to generate a voxel-to-voxel motion matrix between the two CT sets. The motion is equally divided into 5 steps from inspiration to expiration and 5 steps from expiration to inspiration, generating a total of 8 phases of interpolated CT sets. An average CT image is generated from all the 10 phase CT images, including original inhale/exhale CT and 8 interpolated CT sets. Quantitative comparison shows that the reduction of image misalignment artifacts using the average CT from the interpolation technique for PET attenuation correction is at a similar level as that using cine average CT, while the dose to the patient from the CT scans is reduced significantly. The interpolated average CT method hence provides a low dose alternative to cine CT scans for PET attenuation correction.

  12. Dynamic response of the occipito-atlanto-axial (C0-C1-C2) complex in right axial rotation.

    PubMed

    Chang, H; Gilbertson, L G; Goel, V K; Winterbottom, J M; Clark, C R; Patwardhan, A

    1992-05-01

    The torque-angular deformation in right axial rotation until failure of the ligamentous occipito-atlanto-axial complex subjected to variable loading rate (dynamic) axial torque was characterized using a biaxial MTS system. A special fixture and gear box that permitted right axial rotation of the specimen until failure without imposing any additional constraints were used to obtain the data. The specimens were divided into three groups and tested until failure at three different dynamic loading rates: 50, 100, and 400 degrees/s. A previous study by the authors provided data for quasi-static (4 degrees/s) loading conditions. The torque versus rotation curves can be divided into two straight regions and two transition zones. The plots clearly indicated that at loading rates higher than 4 degrees/s, the specimens became stiffer in the region of steadily increasing resistance prior to failure. The increase in stiffness was maximum at 100 degrees/s. The stiffness decreased somewhat at 400 degrees/s in comparison with 100 degrees/s, but this decrease was not significant. The resulting torque-right axial rotation curves were also examined to estimate the magnitude of maximum resistance (torque) and the corresponding angular rotation value. The average maximum resistance torque increased from 13.6 Nm at 4 degrees/s to 27.8 Nm at 100 degrees/s. The corresponding right angular rotation data (65-78 degrees), however, did not show any significant variation with loading rate. Posttest dissection of the specimens indicated that the type of injury observed was related to the rate of axial loading imposed on a specimen during testing.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. A comparative analysis of the dependences of the hemodynamic parameters on changes in ROI's position in perfusion CT scans

    NASA Astrophysics Data System (ADS)

    Choi, Yong-Seok; Cho, Jae-Hwan; Namgung, Jang-Sun; Kim, Hyo-Jin; Yoon, Dae-Young; Lee, Han-Joo

    2013-05-01

    This study performed a comparative analysis of cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and mean time-to-peak (TTP) obtained by changing the region of interest's (ROI) anatomical positions, during CT brain perfusion. We acquired axial source images of perfusion CT from 20 patients undergoing CT perfusion exams due to brain trauma. Subsequently, the CBV, CBF, MTT, and TTP values were calculated through data-processing of the perfusion CT images. The color scales for the CBV, CBF, MTT, and TTP maps were obtained using the image data. Anterior cerebral artery (ACA) was taken as the standard ROI for the calculations of the perfusion values. Differences in the hemodynamic average values were compared in a quantitative analysis by placing ROI and the dividing axial images into proximal, middle, and distal segments anatomically. By performing the qualitative analysis using a blind test, we observed changes in the sensory characteristics by using the color scales of the CBV, CBF, and MTT maps in the proximal, middle, and distal segments. According to the qualitative analysis, no differences were found in CBV, CBF, MTT, and TTP values of the proximal, middle, and distal segments and no changes were detected in the color scales of the the CBV, CBF, MTT, and TTP maps in the proximal, middle, and distal segments. We anticipate that the results of the study will useful in assessing brain trauma patients using by perfusion imaging.

  14. CT angiography - arms and legs

    MedlinePlus

    ... combines a CT scan with the injection of dye. This technique is able to create pictures of ... Some exams require a special dye, called contrast, to be injected into your body before the test. Contrast helps certain areas show up better on the x- ...

  15. Pocket atlas of normal CT anatomy

    SciTech Connect

    Weinstein, J.B.; Lee, J.K.T.; Sagel, S.S.

    1985-01-01

    This book is a quick reference for interpreting CT scans of the extracranial organs. This collection of 41 CT scans covers all the major organs of the body: neck and larynx; chest; abdomen; male pelvis; and female pelvis.

  16. Validation of calculation algorithms for organ doses in CT by measurements on a 5 year old paediatric phantom

    NASA Astrophysics Data System (ADS)

    Dabin, Jérémie; Mencarelli, Alessandra; McMillan, Dayton; Romanyukha, Anna; Struelens, Lara; Lee, Choonsik

    2016-06-01

    Many organ dose calculation tools for computed tomography (CT) scans rely on the assumptions: (1) organ doses estimated for one CT scanner can be converted into organ doses for another CT scanner using the ratio of the Computed Tomography Dose Index (CTDI) between two CT scanners; and (2) helical scans can be approximated as the summation of axial slices covering the same scan range. The current study aims to validate experimentally these two assumptions. We performed organ dose measurements in a 5 year-old physical anthropomorphic phantom for five different CT scanners from four manufacturers. Absorbed doses to 22 organs were measured using thermoluminescent dosimeters for head-to-torso scans. We then compared the measured organ doses with the values calculated from the National Cancer Institute dosimetry system for CT (NCICT) computer program, developed at the National Cancer Institute. Whereas the measured organ doses showed significant variability (coefficient of variation (CoV) up to 53% at 80 kV) across different scanner models, the CoV of organ doses normalised to CTDIvol substantially decreased (12% CoV on average at 80 kV). For most organs, the difference between measured and simulated organ doses was within  ±20% except for the bone marrow, breasts and ovaries. The discrepancies were further explained by additional Monte Carlo calculations of organ doses using a voxel phantom developed from CT images of the physical phantom. The results demonstrate that organ doses calculated for one CT scanner can be used to assess organ doses from other CT scanners with 20% uncertainty (k  =  1), for the scan settings considered in the study.

  17. Pathological investigation of caries and occlusal pulpar exposure in donkey cheek teeth using computerised axial tomography with histological and ultrastructural examinations.

    PubMed

    Toit, Nicole du; Burden, Faith A; Kempson, Sue A; Dixon, Padraic M

    2008-12-01

    Post-mortem examination of 16 donkey cheek teeth (CT) with caries (both peripheral and infundibular) and pulpar exposure were performed using computerised axial tomography (CAT), histology and scanning electron microscopy. CAT imaging was found to be useful to assess the presence and extent of caries and pulp exposure in individual donkey CT. Histology identified the loss of occlusal secondary dentine, and showed pulp necrosis in teeth with pulpar exposure. Viable pulp was present more apically in one exposed pulp horn, with its occlusal aspect sealed off from the exposed aspect of the pulp horn by a false pulp stone. Scanning electron microscopy showed the amelo-cemental junction to be a possible route of bacterial infection in infundibular cemental caries. The basic pathogenesis of dental caries in donkeys appears very similar to its description in other species.

  18. Abdominal CT findings in small bowel perforation.

    PubMed

    Zissin, R; Osadchy, A; Gayer, G

    2009-02-01

    Small bowel perforation is an emergent medical condition for which the diagnosis is usually not made clinically but by CT, a common imaging modality used for the diagnosis of acute abdomen. Direct CT features that suggest perforation include extraluminal air and oral contrast, which are often associated with secondary CT signs of bowel pathology. This pictorial review illustrates the CT findings of small bowel perforation caused by various clinical entities.

  19. CT Scans - Multiple Languages: MedlinePlus

    MedlinePlus

    ... الأشعة المقطعية الحاسوبية - العربية Bilingual PDF Health Information Translations Chinese - Simplified (简体中文) CT (Computerized Tomography) Scan CT ( ... 扫描 - 简体中文 (Chinese - Simplified) Bilingual PDF Health Information Translations Chinese - Traditional (繁體中文) CT (Computerized Tomography) Scan CT ( ...

  20. Electromagnetic fields in axial symmetric waveguides with variable cross section

    SciTech Connect

    Kheifets, S.

    1980-02-15

    A new class of separable variables is found which allows one to find an approximate analytical solution of the Maxwell equations for axial symmetric waveguides with slow (but not necessarily small) varying boundary surfaces. An example of the solution is given. Possible applications and limitations of this approach are discussed. 6 refs., 10 figs.

  1. Optimal design of multi-conditions for axial flow pump

    NASA Astrophysics Data System (ADS)

    Shi, L. J.; Tang, F. P.; Liu, C.; Xie, R. S.; Zhang, W. P.

    2016-11-01

    Passage components of the pump device will have a negative flow state when axial pump run off the design condition. Combined with model tests of axial flow pump, this paper use numerical simulation and numerical optimization techniques, and change geometric design parameters of the impeller to optimal design of multi conditions for Axial Flow Pump, in order to improve the efficiency of non-design conditions, broad the high efficient district and reduce operating cost. The results show that, efficiency curve of optimized significantly wider than the initial one without optimization. The efficiency of low flow working point increased by about 2.6%, the designed working point increased by about 0.5%, and the high flow working point increased the most, about 7.4%. The change range of head is small, so all working point can meet the operational requirements. That will greatly reduce operating costs and shorten the period of optimal design. This paper adopted the CFD simulation as the subject analysis, combined with experiment study, instead of artificial way of optimization design with experience, which proves the reliability and efficiency of the optimization design of multi-operation conditions of axial-flow pump device.

  2. A survey of unclassified axial-flow-compressor literature

    NASA Technical Reports Server (NTRS)

    Herzig, Howard Z; Hansen, Arthur G

    1955-01-01

    A survey of unclassified axial-flow-compressor literature is presented in the form of brief reviews of the methods, results, and conclusions of selected reports. The reports are organized into several main categories with subdivisions, and frequent references are made within the individual reviews to pertinent material elsewhere in the survey.

  3. Magnetically suspended centrifugal blood pump with an axially levitated motor.

    PubMed

    Masuzawa, Toru; Ezoe, Shiroh; Kato, Tsuyoshi; Okada, Yohji

    2003-07-01

    The longevity of a rotary blood pump is mainly determined by the durability of its wearing mechanical parts such as bearings and seals. Magnetic suspension techniques can be used to eliminate these mechanical parts altogether. This article describes a magnetically suspended centrifugal blood pump using an axially levitated motor. The motor comprises an upper stator, a bottom stator, and a levitated rotor-impeller between the stators. The upper stator has permanent magnets to generate an attractive axial bias force on the rotor and electric magnets to control the inclination of the rotor. The bottom stator has electric magnets to generate attractive forces and rotating torque to control the axial displacement and rotation of the rotor. The radial displacement of the rotor is restricted by passive stability. A shrouded impeller is integrated within the rotor. The performance of the magnetic suspension and pump were evaluated in a closed mock loop circuit filled with water. The maximum amplitude of the rotor displacement in the axial direction was only 0.06 mm. The maximum possible rotational speed during levitation was 1,600 rpm. The maximum pressure head and flow rate were 120 mm Hg and 7 L/min, respectively. The pump shows promise as a ventricular assist device.

  4. Performance analysis of axial-flow mixing impellers

    SciTech Connect

    Wu, J.; Pullum, L.

    2000-03-01

    Theoretical formulations for impeller performance were evaluated based on a blade-element theory. These enable the calculation of the head and power vs. flow-rate curves of axial-flow impellers. The technique uses the life and drag coefficients of the blade section of an impeller to calculate the spanwise swirl-velocity distribution. Using the angular-momentum equation, it is possible to calculate the corresponding spanwise distribution of the energy head of the impeller. Integration of these distributions of head and torque gives the impeller's performance. Parameters including the flow number, the power number, the thrust force number, and the swirl velocity can be found at the impeller operating point, determined using the head curve and an experimentally calibrated resistance curve. A laser Doppler velocimetry (LDV) system was used to measure the velocity distribution for different axial flow impellers in mixing tanks. Calculated flow and power numbers agreed well with the experimental results. Using the blade's spanwise head distribution and a set of calibrated flow-resistance data, it is also possible to estimate an impeller's outlet axial-velocity distribution. Predictions compared well with LDV experimental data. The effect of impeller-blade angle, number of blades, blade camber, and blade thickness on the performance of axial-flow impellers was investigated using the Agitator software.

  5. Axial dispersion in flowing red blood cell suspensions

    NASA Astrophysics Data System (ADS)

    Podgorski, Thomas; Losserand, Sylvain; Coupier, Gwennou

    2016-11-01

    A key parameter in blood microcirculation is the transit time of red blood cells (RBCs) through an organ, which can influence the efficiency of gas exchange and oxygen availability. A large dispersion of this transit time is observed in vivo and is partly due to the axial dispersion in the flowing suspension. In the classic Taylor-Aris example of a solute flowing in a tube, the combination of molecular diffusion and parabolic velocity profile leads to enhanced axial dispersion. In suspensions of non-Brownian deformable bodies such as RBCs, axial dispersion is governed by a combination of shear induced migration and shear-induced diffusion arising from hydrodynamic interactions. We revisit this problem in the case of RBC pulses flowing in a microchannel and show that the axial dispersion of the pulse eventually saturates with a final extension that depends directly on RBC mechanical properties. The result is especially interesting in the dilute limit since the final pulse length depends only on the channel width, exponent of the migration law and dimensionless migration velocity. In continuous flow, the dispersion of transit times is the result of complex cell-cell and cell-wall interactions and is strongy influenced by the polydispersity of the blood sample. The authors acknowledge support from LabEx TEC21 and CNES.

  6. 13. Axial view to south through truss span. In addition ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Axial view to south through truss span. In addition to repaired vertical compression members visible on upstream (right) side and new sway bracing overhead, note also spliced diagonal tension member on downstream (left) side. - Stanislaus River Bridge, Atchison, Topeka & Santa Fe Railway at Stanislaus River, Riverbank, Stanislaus County, CA

  7. 8. Axial view to south of north portal of truss ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Axial view to south of north portal of truss span. Note boxed, repaired vertical compression members at left (upstream) side of truss, new I-beam braces between compression members and upper sway bracing. - Stanislaus River Bridge, Atchison, Topeka & Santa Fe Railway at Stanislaus River, Riverbank, Stanislaus County, CA

  8. 11. Axial view of west bay, view to east. Transverse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Axial view of west bay, view to east. Transverse wall at end of space was installed after cessation of railway use. - Interurban Electric Railway Bridge Yard Shop, Interstate 80 at Alameda County Postmile 2.0, Oakland, Alameda County, CA

  9. Evaluation of Satisfaction and Axial Rigidity with Titan XL Cylinders

    PubMed Central

    Henry, Gerard D.; Jennermann, Caroline; Eid, J. Francois

    2012-01-01

    The inflatable penile prosthesis (IPP) has high patient satisfaction rates and good mechanical reliability rates in multiple studies. The number one patient compliant at six months is penile length. Recently, new technique for aggressive sizing of the cylinders has been published on in the literature. One IPP company has produced a new product that has longer length cylinders (XL) than those available. However, traditionally long cylinders were felt to lack axial rigidity. Therefore, a prospective, multicenter, central IRB-approved, monitored study was performed on the new product to address these concerns. At 2 centers, a total of 17 patients underwent surgical implantation of these new XL cylinders. These patients were questioned for patient satisfaction and tested for axial rigidity using a Fastsize Erectile Quality Monitor. The results showed excellent patient satisfaction rates and great axial rigidity with the Fastsize Erectile Quality Monitor. The XL cylinders appear to give the IPP surgeon the ability to use longer cylinders with good patient satisfaction and great axial rigidity. PMID:22997510

  10. Modifications to Axially Symmetric Simulations Using New DSMC (2007) Algorithms

    NASA Technical Reports Server (NTRS)

    Liechty, Derek S.

    2008-01-01

    Several modifications aimed at improving physical accuracy are proposed for solving axially symmetric problems building on the DSMC (2007) algorithms introduced by Bird. Originally developed to solve nonequilibrium, rarefied flows, the DSMC method is now regularly used to solve complex problems over a wide range of Knudsen numbers. These new algorithms include features such as nearest neighbor collisions excluding the previous collision partners, separate collision and sampling cells, automatically adaptive variable time steps, a modified no-time counter procedure for collisions, and discontinuous and event-driven physical processes. Axially symmetric solutions require radial weighting for the simulated molecules since the molecules near the axis represent fewer real molecules than those farther away from the axis due to the difference in volume of the cells. In the present methodology, these radial weighting factors are continuous, linear functions that vary with the radial position of each simulated molecule. It is shown that how one defines the number of tentative collisions greatly influences the mean collision time near the axis. The method by which the grid is treated for axially symmetric problems also plays an important role near the axis, especially for scalar pressure. A new method to treat how the molecules are traced through the grid is proposed to alleviate the decrease in scalar pressure at the axis near the surface. Also, a modification to the duplication buffer is proposed to vary the duplicated molecular velocities while retaining the molecular kinetic energy and axially symmetric nature of the problem.

  11. Quantifying the eruption cycle at Axial Seamount using submarine geodesy

    NASA Astrophysics Data System (ADS)

    Nooner, S. L.; Chadwick, B.

    2011-12-01

    Bottom pressure instruments within the caldera of Axial Seamount recorded subsidence during eruptions in 1998 and again in April 2011, for a total repeat time of 13 years. We present here a summary of the vertical deformation history at Axial and describe what that tells us about changes in magma supply over an entire eruption cycle. Over the last 13 years we have used a combination of continuously recording bottom pressure recorder (BPR) instruments and campaign style mobile pressure recorder (MPR) surveys to document changes in the elevation of the caldera floor. These observations of caldera deformation directly reflect changes in the magmatic system throughout the entire volcanic eruption cycle. Rapid inflation of the volcano (>50 cm/yr) started immediately after the 1998 eruption and began slowing exponentially within a few months, ultimately transitioning to a constant linear inflation rate of 15 cm/yr that continued until the 2011 eruption. We interpret these two different inflation regimes as the surface manifestation of two entirely different recharge mechanisms within the magma chamber: 1) Short-duration poroelastic flow and viscoelastic relaxation immediately following eruption, and 2) Long-term linear recharge from the mantle. The second mechanism suggests that long-term flow rates from the mantle are controlled by permeability rather than pressure at Axial. Finally, we present evidence that the pattern of deformation at Axial can be used as a method of forecasting future eruptions here.

  12. Dynamics of Axial Separation in Long Rotating Drums

    SciTech Connect

    Aranson, I.S.; Tsimring, L.S.

    1999-06-01

    We propose a continuum description for the axial separation of granular materials in a long rotating drum. The model, operating with two local variables, concentration difference and the dynamic angle of repose, describes both initial transient traveling wave dynamics and long-term segregation of the binary mixture. Segregation proceeds through ultraslow logarithmic coarsening. {copyright} {ital 1999} {ital The American Physical Society}

  13. 247. Axial Parkway alignment along ridge top. Note the open ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    247. Axial Parkway alignment along ridge top. Note the open vistas to either side of the roadway. These are maintained through vegetation management. The wood guide rail is a primary safety feature. View is to the northeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  14. Axial-Loading Circumferential Dovetail Turbine-Blade Mount

    NASA Technical Reports Server (NTRS)

    Pierce, Martin J.; Ward, Steven D.; Eskridge, Ronald R.

    1992-01-01

    In new configuration, retaining ring holds base of blades in circumferential dovetail slot. Blades inserted axially via loading slots into circumferential dovetail slot. Ring placed over loading slots and fastened with split ring held by arm of disk. Blades less likely to be shaken loose during operation.

  15. Axial alignment fixtures for tension tests of threaded specimens

    NASA Technical Reports Server (NTRS)

    Jones, M. H.; Bubsey, R. T.; Succop, G.; Brown, W. F., Jr.

    1974-01-01

    Description of two axial alignment fixtures that are capable of providing very low load application eccentricity in tension tests of threaded notched cylindrical specimens. The described fixtures are simple in design, very compact, and free from the effects of friction. Also, an evaluation procedure is presented that can be used to qualify any fixture for use in sharp notch tensile tests.

  16. Axial-Gap Induction Motor For Levitated Specimens

    NASA Technical Reports Server (NTRS)

    Sridharan, Govind; Rhim, Won-Kyu; Barber, Dan; Chung, Sang

    1992-01-01

    Motor does not obscure view of specimen. Axial-gap induction motor applies torque to rotate electrostatically or electromagnetically levitated specimen of metal. Possible applications include turning specimens for uniform heating under focused laser beams and obtaining indirect measurements of resistivities or of surface tensions in molten specimens.

  17. Novel axially disubstituted non-aggregated silicon phthalocyanines.

    PubMed

    Bıyıklıoğlu, Zekeriya; Cakır, Dilek

    2012-12-01

    This paper describes the synthesis, spectroscopic characterization of a range of new axially-disubstituted silicon phthalocyanines with 2-[2-(dimethylamino)ethoxy] or 2-[2-(1,4,7,10,13-pentaoxa-16-azacyclooctadecan-16-yl)ethoxy] groups as axial ligands. 2-[2-(Dimethylamino)ethoxy]ethanol 2, 2-[2-(1,4,7,10,13-pentaoxa-16-azacyclooctadecan-16-yl)ethoxy]ethanol 4 are reacted with silicon phthalocyanine 1, to give an axially-disubstituted silicon phthalocyanines 3 and 5. Axially-disubstituted silicon phthalocyanine complexes were synthesized at the first time. Newly synthesized silicon phthalocyanines were characterized by UV-Vis, IR, (1)H NMR, (13)C NMR spectroscopy, ESI mass spectrometry. These new silicon(IV) phthalocyanines 3 and 5 showed excellent solubility in organic solvents such as CHCl(3), CH(2)Cl(2), acetone, DMF, DMSO, THF, EtOAc. The aggregation behavior of these compounds were investigated in different concentrations of DMSO. The effect of solvents on absorption spectra were studied in various organic solvents. The thermal stabilities of the silicon(IV) phthalocyanines 3 and 5 were determined by thermogravimetric analysis.

  18. Momentos centrados en sistemas estelares a simetria axial.

    NASA Astrophysics Data System (ADS)

    Sanz Subirana, J.; Juan Zornoza, J. M.; Català Poch, M. A.

    Centered moments in the galactic plane have been analytically determined up to the fourth order for a non-stationary stellar system model with a distribution of peculiar velocities of the stars symmetric under point-axial transformations and equatorial plane reflexions. The obtained results explain satisfactorily the peculiar velocities distribution of the considered stellar samples in the solar neighborhood.

  19. Etanercept for the treatment of non-radiographic axial spondyloarthritis.

    PubMed

    Rios Rodriguez, Valeria; Poddubnyy, Denis

    2016-01-01

    Presently, tumor necrosis factor α antagonist therapy is the only effective alternative treatment to nonsteroidal anti-inflammatory drugs for the entire spectrum of axial spondyloarthritis, including non-radiographic and radiographic (=ankylosing spondylitis) forms. Recently, etanercept has been approved by the European Medicines Agency for the treatment of non-radiographic axial spondyloarthritis, increasing the number of available treatment options for this indication. The latest data on etanercept concerning clinical efficacy and safety in short-term and long-term treatment of patients with non-radiographic axial spondyloarthritis who do not respond to the first-line therapy with non-steroidal anti-inflammatory drugs suggests good efficacy and safety profiles similar to that observed previously in ankylosing spondylitis. This article reviews recent data on the efficacy and safety of etanercept and is focused on the treatment of non-radiographic axial spondyloarthritis. This article will also discuss the role of etanercept in the context of current and developing treatment options.

  20. Fission gas retention and axial expansion of irradiated metallic fuel

    SciTech Connect

    Fenske, G.R.; Emerson, J.E.; Savoie, F.E.; Johanson, E.W.

    1986-05-01

    Out-of-reactor experiments utilizing direct electrical heating and infrared heating techniques were performed on irradiated metallic fuel. The results indicate accelerated expansion can occur during thermal transients and that the accelerated expansion is driven by retained fission gases. The results also demonstrate gas retention and, hence, expansion behavior is a function of axial position within the pin.

  1. On the Applications of Axial Representation of Trigonometric Functions

    ERIC Educational Resources Information Center

    Siadat, M. Vali

    2006-01-01

    In terms of modern pedagogy, having visual interpretation of trigonometric functions is useful and quite helpful. This paper presents, pictorially, an easy approach to prove all single angle trigonometric identities on the axes. It also discusses the application of axial representation in calculus--finding the derivative of trigonometric functions.

  2. Potential sources of artefact in the co-axial bioassay.

    PubMed

    Gunn, L K; Piper, P J

    1991-10-22

    The apparent release of relaxant activity from airway epithelium (epithelium-derived relaxing factor, EpDRF) has been examined in a co-axial bioassay system. The endothelium-denuded rat aorta, placed inside either the epithelium-intact guinea-pig trachea or rabbit bronchus relaxed in response to acetylcholine. In a modification of the standard preparation, the airway was slit longitudinally and immobilised inside a silicone rubber tube. Under these conditions, the acetylcholine-induced relaxation was abolished. Under the conditions of the co-axial bioassay, the oxygen tension in the lumen of either airway tube was lower than that of the bathing fluid. Upon addition of acetylcholine at concentrations which caused relaxation in the co-axial bioassay, the oxygen tension inside the epithelium-intact, but not the epithelium-denuded guinea-pig trachea was depressed to levels which would have affected the contractile response of a rat aorta. We suggest that the assay of relaxant activity from airways using co-axial preparations may be complicated by changes in volume and oxygen tension in the lumen of the donor airway and discuss how such problems might be avoided.

  3. Perturbation approximation for orbits in axially symmetric funnels

    NASA Astrophysics Data System (ADS)

    Nauenberg, Michael

    2014-11-01

    A perturbation method that can be traced back to Isaac Newton is applied to obtain approximate analytic solutions for objects sliding in axially symmetric funnels in near circular orbits. Some experimental observations are presented for balls rolling in inverted cones with different opening angles, and in a funnel with a hyperbolic surface that approximately simulates the gravitational force.

  4. Cyclone reactor with internal separation and axial recirculation

    DOEpatents

    Becker, F.E.; Smolensky, L.A.

    1988-07-19

    A cyclone combustor apparatus contains a circular partition plate containing a central circular aperture is described. The partition plate divides the apparatus into a cylindrical precombustor chamber and a combustor chamber. A coal-water slurry is passed axially into the inlet end of the precombustor chamber, and primary air is passed tangentially into said chamber to establish a cyclonic air flow. Combustion products pass through the partition plate aperture and into the combustor chamber. Secondary air may also be passed tangentially into the combustor chamber adjacent the partition plate to maintain the cyclonic flow. Flue gas is passed axially out of the combustor chamber at the outlet end and ash is withdrawn tangentially from the combustor chamber at the outlet end. A first mixture of flue gas and ash may be tangentially withdrawn from the combustor chamber at the outlet end and recirculated to the axial inlet of the precombustor chamber with the coal-water slurry. A second mixture may be tangentially withdrawn from the outlet end and passed to a heat exchanger for cooling. Cooled second mixture is then recirculated to the axial inlet of the precombustor chamber. In another embodiment a single cyclone combustor chamber is provided with both the recirculation streams of the first mixture and the second mixture. 10 figs.

  5. Cyclone reactor with internal separation and axial recirculation

    DOEpatents

    Becker, Frederick E.; Smolensky, Leo A.

    1989-01-01

    A cyclone combustor apparatus contains a circular partition plate containing a central circular aperture. The partition plate divides the apparatus into a cylindrical precombustor chamber and a combustor chamber. A coal-water slurry is passed axially into the inlet end of the precombustor chamber, and primary air is passed tangentially into said chamber to establish a cyclonic air flow. Combustion products pass through the partition plate aperture and into the combustor chamber. Secondary air may also be passed tangentially into the combustor chamber adjacent the partition plate to maintain the cyclonic flow. Flue gas is passed axially out of the combustor chamber at the outlet end and ash is withdrawn tangentially from the combuston chamber at the outlet end. A first mixture of flue gas and ash may be tangentially withdrawn from the combustor chamber at the outlet end and recirculated to the axial inlet of the precombustor chamber with the coal-water slurry. A second mixture of flue gas and ash may be tangentially withdrawn from the outlet end of the combustor chamber and passed to a heat exchanger for cooling. Cooled second mixture is then recirculated to the axial inlet of the precombustor chamber. In another embodiment a single cyclone combustor chamber is provided with both the recirculation streams of the first mixture and the second mixture.

  6. Hydrostatic self-aligning axial/torsional mechanism

    DOEpatents

    O'Connor, Daniel G.; Gerth, Howard L.

    1990-01-01

    The present invention is directed to a self-aligning axial/torsional loading mechanism for testing the strength of brittle materials which are sensitive to bending moments. Disposed inside said self-aligning loading mechanism is a frictionless hydrostatic ball joint with a flexure ring to accommodate torsional loads through said ball joint.

  7. Elevated temperature axial and torsional fatigue behavior of Haynes 188

    NASA Technical Reports Server (NTRS)

    Bonacuse, Peter J.; Kalluri, Sreeramesh

    1995-01-01

    The results are reported for high-temperature axial and torsional low-cycle fatigue experiments performed at 760 C in air on thin-walled tubular specimens of Haynes 188, a wrought cobalt-based superalloy. Data are also presented for mean coefficient of thermal expansion, elastic modulus, and shear modulus at various temperatures from room to 1000 C, and monotonic and cyclic stress-strain curves in tension and in shear at 760 C. This data set is used to evaluate several multiaxial fatigue life models (most were originally developed for room temperature multiaxial life prediction) including von Mises equivalent strain range (ASME Boiler and Pressure Code), Manson-Halford, modified multiaxiality factor (proposed in this paper), modified Smith-Watson-Topper, and Fatemi-Socie-Kurath. At von Mises equivalent strain ranges (the torsional strain range divided by the square root of 3, taking the Poisson's ratio to be 0.5), torsionally strained specimens lasted, on average, factors of 2 to 3 times longer than axially strained specimens. The modified multiaxiality factor approach shows promise as a useful method of estimating torsional fatigue life from axial fatigue data at high temperatures. Several difficulties arose with the specimen geometry and extensometry used in these experiments. Cracking at extensometer probe indentations was a problem at smaller strain ranges. Also, as the largest axial and torsional strain range fatigue tests neared completion, a small amount of specimen buckling was observed.

  8. Elevated temperature axial and torsional fatigue behavior of Haynes 188

    NASA Technical Reports Server (NTRS)

    Bonacuse, Peter J.; Kalluri, Sreeramesh

    1992-01-01

    The results of high-temperature axial and torsional low-cycle fatigue experiments performed on Haynes 188, a wrought cobalt-base superalloy, are reported. Fatigue tests were performed at 760 C in air on thin-walled tubular specimens at various ranges under strain control. Data are also presented for coefficient of thermal expansion, elastic modulus, and shear modulus at various temperatures from room to 1000 C, and monotonic and cyclic stress-strain curves in tension and in shear at 760 C. The data set is used to evaluate several multiaxial fatigue life models (most were originally developed for room temperature multiaxial life prediction) including von Mises equivalent strain range (ASME boiler and pressure vessel code), Manson-Halford, Modified Multiaxiality Factor (proposed here), Modified Smith-Watson-Topper, and Fatemi-Socie-Kurath. At von Mises equivalent strain ranges (the torsional strain range divided by the square root of 3, taking the Poisson's ratio to be 0.5), torsionally strained specimens lasted, on average, factors of 2 to 3 times longer than axially strained specimens. The Modified Multiaxiality Factor approach shows promise as a useful method of estimating torsional fatigue life from axial fatigue data at high temperatures. Several difficulties arose with the specimen geometry and extensometry used in these experiments. Cracking at extensometer probe indentations was a problem at smaller strain ranges. Also, as the largest axial and torsional strain range fatigue tests neared completion, a small amount of specimen buckling was observed.

  9. [Periinterventional cone-beam-CT: application at transarterial chemoembolization of liver tumors].

    PubMed

    Adamus, R; Uder, M; Wilhelm, M; Loose, R W

    2011-07-01

    Periinterventional Cone-Beam CT (CBCT) today is a valuable tool in complex radiological interventions. Only little experience exists about CBCT in transarterial chemoembolisations (TACE) of liver tumors. 25 patients underwent periinterventional CBCT. We used a C-arc DSA with 30 × 40 cm flat panel detector. Image data with axial, coronal and 3D-reconstruction were acquired by 217° rotation in 8 seconds. In all 25 cases CBCT had an influence on the TACE regarding the decision which vessels to catheterize, the amount of retention of the embolisation agent or an abort because of insufficient vascularisation. In comparison with DSA alone, CBCT allows a better visualisation of tumour vessels, simplifies selective catheterisation, the decision whether an embolisation is possible and enables a good visualisation of Lipiodol retention. Hence, CBCT is a helpful periinterventional tool but cannot substitute CT and MRI in follow up.

  10. Micro-CT of Carotid Arteries: A Tool for Experimental Studies

    SciTech Connect

    Mohr, Andreas; Wenke, Ruediger; Roemer, Frank W.; Lynch, John A.; Gatzka, Christian; Priebe, Markus; Guermazi, Ali; Grigorian, Mikayel; Heller, Martin; Mueller-Huelsbeck, Stefan

    2004-11-15

    Micro-computed tomography (micro-CT) is a high-resolution, nondestructive tool for two- and three-dimensional imaging and quantification. The ability of this technique to assess atherosclerosis of the carotid artery was evaluated in three human cadaver samples based on the original axial acquisitions, multiplanar reconstructions and volume rendering techniques. Quantitative analysis included the calculation of: (1) the original lumen perimeter, original lumen area, plaque area, residual lumen area, calcified area and gross sectional area reduction of the vascular lumen from two-dimensional slices; (2) the total tissue volume, soft tissue volume and calcified tissue volume from the three-dimensional data set. This preliminary study demonstrates the potential of micro-CT as a supplementary method for the two- and three-dimensional ex vivo evaluation of carotid atherosclerosis.

  11. Axial differentiation and early gastrulation stages of the pig embryo.

    PubMed

    Hassoun, Romia; Schwartz, Peter; Feistel, Kerstin; Blum, Martin; Viebahn, Christoph

    2009-12-01

    Differentiation of the principal body axes in the early vertebrate embryo is based on a specific blueprint of gene expression and a series of transient axial structures such as Hensen's node and the notochord of the late gastrulation phase. Prior to gastrulation, the anterior visceral endoderm (AVE) of the mouse egg-cylinder or the anterior marginal crescent (AMC) of the rabbit embryonic disc marks the anterior pole of the embryo. For phylogenetic and functional reasons both these entities are addressed here as the mammalian anterior pregastrulation differentiation (APD). However, mouse and rabbit show distinct structural differences in APD and the molecular blueprint, making the search of general rules for axial differentiation in mammals difficult. Therefore, the pig was analysed here as a further species with a mammotypical flat embryonic disc. Using light and electron microscopy and in situ hybridisation for three key genes involved in early development (sox17, nodal and brachyury), two axial structures of early gastrulation in the pig were identified: (1) the anterior hypoblast (AHB) characterised by increased cellular height and density and by sox17 expression, and (2) the early primitive streak characterised by a high pseudostratified epithelium with an almost continuous but unusually thick basement membrane, by localised epithelial-mesenchymal transition, and by brachyury expression in the epiblast. The stepwise appearance of these two axial structures was used to define three stages typical for mammals at the start of gastrulation. Intriguingly, the round shape and gradual posterior displacement of the APD in the pig appear to be species-specific (differing from all other mammals studied in detail to date) but correlate with ensuing specific primitive streak and extraembryonic mesoderm development. APD and, hence, the earliest axial structure presently known in the mammalian embryo may thus be functionally involved in shaping extraembryonic membranes and

  12. SU-E-T-93: Creation of Standardized APBI SAVI Cavities Using CT Registration

    SciTech Connect

    Dahl, R

    2014-06-01

    Purpose: Develop a consistent and rapid method of generating the initial cavity structure for Accelerated Partial Breast Irradiation (APBI) using the SAVI applicator. Methods: Four SAVI (Cianna Medical) applicators (6-1 Mini, 6-1, 8-1, and 10-1) were scanned on a CT simulator. The applicators were scanned in air with the CT slices (0.625mm axial thickness) perpendicular to the long axis of the applicator. Following scanning the CT images were transferred to Eclipse (Varian Medical Systems) and contours of the cavity were drawn. The cavity proximal and distal locations were defined according to MD specification. The scans and contours were then re-imported into the CT virtual simulation workstation.At the time of patient planning the appropriate applicator scan is anonymized and imported into Eclipse. In Brachytherapy Planning two Marker points are placed, one at the distal band location (cavity start) and the second at a defined distance along the applicator (cavity end). The actual patient scan is then registered to the applicator scan. A three point match is used to quickly get the two scans in approximate alignment. Manually matching is then used to fine tune the alignment of the cavity contour and Marker points. Results: The standard applicator scans have shown to agree well with the applicators in the patient scans. The time taken to register the scans has shown to be less than generating the cavities using the standard methods of contouring on the axial slices or using the dose shaper with sources in the central channel. Conclusion: The registration of a standard applicator scan and contour has improved the consistency in the generation of the initial cavity (SAVI) structure. Planning structures used for dose calculation are created with that structure as a starting point so accuracy and consistency are important for dose evaluation and plan comparison.

  13. Embedding of human vertebral bodies leads to higher ultimate load and altered damage localisation under axial compression.

    PubMed

    Maquer, Ghislain; Schwiedrzik, Jakob; Zysset, Philippe K

    2014-01-01

    Computer tomography (CT)-based finite element (FE) models of vertebral bodies assess fracture load in vitro better than dual energy X-ray absorptiometry, but boundary conditions affect stress distribution under the endplates that may influence ultimate load and damage localisation under post-yield strains. Therefore, HRpQCT-based homogenised FE models of 12 vertebral bodies were subjected to axial compression with two distinct boundary conditions: embedding in polymethylmethalcrylate (PMMA) and bonding to a healthy intervertebral disc (IVD) with distinct hyperelastic properties for nucleus and annulus. Bone volume fraction and fabric assessed from HRpQCT data were used to determine the elastic, plastic and damage behaviour of bone. Ultimate forces obtained with PMMA were 22% higher than with IVD but correlated highly (R² = 0.99). At ultimate force, distinct fractions of damage were computed in the endplates (PMMA: 6%, IVD: 70%), cortex and trabecular sub-regions, which confirms previous observations that in contrast to PMMA embedding, failure initiated underneath the nuclei in healthy IVDs. In conclusion, axial loading of vertebral bodies via PMMA embedding versus healthy IVD overestimates ultimate load and leads to distinct damage localisation and failure pattern.

  14. Time-Domain Terahertz Computed Axial Tomography NDE System

    NASA Technical Reports Server (NTRS)

    Zimdars, David

    2012-01-01

    NASA has identified the need for advanced non-destructive evaluation (NDE) methods to characterize aging and durability in aircraft materials to improve the safety of the nation's airline fleet. 3D THz tomography can play a major role in detection and characterization of flaws and degradation in aircraft materials, including Kevlar-based composites and Kevlar and Zylon fabric covers for soft-shell fan containment where aging and durability issues are critical. A prototype computed tomography (CT) time-domain (TD) THz imaging system has been used to generate 3D images of several test objects including a TUFI tile (a thermal protection system tile used on the Space Shuttle and possibly the Orion or similar capsules). This TUFI tile had simulated impact damage that was located and the depth of damage determined. The CT motion control gan try was designed and constructed, and then integrated with a T-Ray 4000 control unit and motion controller to create a complete CT TD-THz imaging system prototype. A data collection software script was developed that takes multiple z-axis slices in sequence and saves the data for batch processing. The data collection software was integrated with the ability to batch process the slice data with the CT TD-THz image reconstruction software. The time required to take a single CT slice was decreased from six minutes to approximately one minute by replacing the 320 ps, 100-Hz waveform acquisition system with an 80 ps, 1,000-Hz waveform acquisition system. The TD-THZ computed tomography system was built from pre-existing commercial off-the-shelf subsystems. A CT motion control gantry was constructed from COTS components that can handle larger samples. The motion control gantry allows inspection of sample sizes of up to approximately one cubic foot (.0.03 cubic meters). The system reduced to practice a CT-TDTHz system incorporating a COTS 80- ps/l-kHz waveform scanner. The incorporation of this scanner in the system allows acquisition of 3D

  15. Pediatric personalized CT-dosimetry Monte Carlo simulations, using computational phantoms

    NASA Astrophysics Data System (ADS)

    Papadimitroulas, P.; Kagadis, G. C.; Ploussi, A.; Kordolaimi, S.; Papamichail, D.; Karavasilis, E.; Syrgiamiotis, V.; Loudos, G.

    2015-09-01

    The last 40 years Monte Carlo (MC) simulations serve as a “gold standard” tool for a wide range of applications in the field of medical physics and tend to be essential in daily clinical practice. Regarding diagnostic imaging applications, such as computed tomography (CT), the assessment of deposited energy is of high interest, so as to better analyze the risks and the benefits of the procedure. The last few years a big effort is done towards personalized dosimetry, especially in pediatric applications. In the present study the GATE toolkit was used and computational pediatric phantoms have been modeled for the assessment of CT examinations dosimetry. The pediatric models used come from the XCAT and IT'IS series. The X-ray spectrum of a Brightspeed CT scanner was simulated and validated with experimental data. Specifically, a DCT-10 ionization chamber was irradiated twice using 120 kVp with 100 mAs and 200 mAs, for 1 sec in 1 central axial slice (thickness = 10mm). The absorbed dose was measured in air resulting in differences lower than 4% between the experimental and simulated data. The simulations were acquired using ∼1010 number of primaries in order to achieve low statistical uncertainties. Dose maps were also saved for quantification of the absorbed dose in several children critical organs during CT acquisition.

  16. Computer-aided diagnosis in CT colonography: detection of polyps based on geometric and texture features

    NASA Astrophysics Data System (ADS)

    Yoshida, Hiroyuki; Naeppi, Janne J.; Frimmel, Hans; Dachman, Abraham H.

    2002-05-01

    A computer-aided diagnosis scheme for the detection of colonic polyps in CT colonography has been developed, and its performance has been assessed based on clinical cases with colonoscopy-confirmed polyps. In the scheme, the colon was automatically segmented by use of knowledge-guided segmentation from 3-dimensional isotropic volumes reconstructed from axial CT slices in CT colonography. Polyp candidates are detected by first computing of 3-dimensional geometric features that characterize polyps, and then segmenting of connected components corresponding to suspicious regions by hysteresis thresholding and fuzzy clustering based on these geometric features. False-positive detections are reduced by computation of 3-dimensional texture features characterizing the internal structures of the polyp candidates, followed by application of discriminant analysis to the feature space generated by the geometric and texture features. We applied our scheme to 43 CT colonographic cases with cleansed colon, including 12 polyps larger than 5 mm. In a by-dataset analysis, the CAD scheme yielded a sensitivity of 95% with 1.2 false positives per data set. The false negative was one of the two polyps in a single patient. Consequently, in by-patient analysis, our method yielded 100% sensitivity with 2.0 false positives per patient. The results indicate that our CAD scheme has the potential to detect clinically important polyp cases with a high sensitivity and a relatively low false-positive rate.

  17. Toxoplasma encephalitis in Haitian adults with acquired immunodeficiency syndrome: a clinical-pathologic-CT correlation

    SciTech Connect

    Post, M.J.D.; Chan, J.C.; Hensley, G.T.; Hoffman, T.A.; Moskowitz, L.B.; Lippmann, S.

    1983-05-01

    The clinical data, histologic findings, and computed tomographic (CT) abnormalities in eight adult Haitians with toxoplasma encephalitis were analyzed retrospectively. Diagnosis was established by identification of Toxoplasma gondii on autopsy in five and brain biopsy in three specimens and subsequently confirmed by the immunoperoxidase method. All these patiens, six of whom had been in the United States for 24 months or less, had severe idiopathic immunodeficiency syndrome. All were lymphopenic and six were on treatment for tuberculosis when the toxoplasma encephalitis developed. All patients were studied with CT when they developed an altered mental status and fever associated with seizures and/or focal neurologic deficits. Scans before treatment showed multiple intraparenchymal lesions in seven and a single lesion in the thalamus in one. Ring and/or nodular enhancement of the lesions was found in six and hypodense areas in two. Progressions of abnormalities occurred on serial studies. These CT findings that were best shown on axial and coronal thin-section double-dose contrast studies were useful but not diagnostically pathognomonic. In patients with similar clinical presentation CT is recommended to identify focal areas of involvement and to guide brain biopsy or excision so that prompt medical thereapy of this often lethal infection can be instituted.

  18. Cervical tuberculous adenitis: CT manifestations

    SciTech Connect

    Reede, D.L.; Bergeron, R.T.

    1985-03-01

    Cervical tuberculous adenitis is being seen with increasing frequency in the United States; in the appropriate clinical setting it should be included in the differential diagnosis of an asymptomatic neck mass. Patients are typically young adults who are recent arrivals from Southeast Asia. A history of tuberculosis is not always elicited nor is the chest radiograph always abnormal. All of these patients have positive purified protein derivative tests unless they are anergic. The CT findings may lead to the diagnosis. Several CT patterns of nodal disease can be seen in tuberculous adenitis; some may mimic benign and neoplastic disease. The presence of a multiloculated or multichambered (conglomerate nodal) mass with central lucency and thick rims of enhancement and minimally effaced fascial planes is highly suggestive of tuberculous adenitis, especially if the patient has a strongly positive tuberculosis skin test.

  19. Dual energy CT for attenuation correction with PET/CT

    SciTech Connect

    Xia, Ting; Alessio, Adam M.; Kinahan, Paul E.

    2014-01-15

    Purpose: The authors evaluate the energy dependent noise and bias properties of monoenergetic images synthesized from dual-energy CT (DECT) acquisitions. These monoenergetic images can be used to estimate attenuation coefficients at energies suitable for positron emission tomography (PET) and single-photon emission computed tomography (SPECT) imaging. This is becoming more relevant with the increased use of quantitative imaging by PET/CT and SPECT/CT scanners. There are, however, potential variations in the noise and bias of synthesized monoenergetic images as a function of energy. Methods: The authors used analytic approximations and simulations to estimate the noise and bias of synthesized monoenergetic images of water-filled cylinders with different shapes and the NURBS-based cardiac-torso (NCAT) phantom from 40 to 520 keV, the range of SPECT and PET energies. The dual-kVp spectra were based on the GE Lightspeed VCT scanner at 80 and 140 kVp with added filtration of 0.5 mm Cu. The authors evaluated strategies of noise suppression with sinogram smoothing and dose minimization with reduction of tube currents at the two kVp settings. The authors compared the impact of DECT-based attenuation correction with single-kVp CT-based attenuation correction on PET quantitation for the NCAT phantom for soft tissue and high-Z materials of bone and iodine contrast enhancement. Results: Both analytic calculations and simulations displayed the expected minimum noise value for a synthesized monoenergetic image at an energy between the mean energies of the two spectra. In addition the authors found that the normalized coefficient of variation in the synthesized attenuation map increased with energy but reached a plateau near 160 keV, and then remained constant with increasing energy up to 511 keV and beyond. The bias was minimal, as the linear attenuation coefficients of the synthesized monoenergetic images were within 2.4% of the known true values across the entire energy range

  20. Deformation associated with the 2015 Eruption of Axial Seamount

    NASA Astrophysics Data System (ADS)

    Nooner, S. L.; Chadwick, W.; Caress, D. W.; Clague, D. A.; Paduan, J. B.; Yoerger, D.; Sasagawa, G. S.

    2015-12-01

    On April 24th 2015, an eruption began at Axial Seamount, a seafloor volcano located about 480 km west of the Oregon coast at the intersection of the Cobb hotspot and the Juan de Fuca Ridge. This eruption was first detected in real time by the newly operational Ocean Observatories Initiative cabled instrumentation at Axial (Delaney, AGU-2015, Wilcock, AGU-2015, Caplan-Auerbach, AGU-2015). Two prior eruptions have been observed since routine observations began in the 1990's, one in January 1998 and the other in April 2011. Precise water pressure measurements made on the volcano have documented an inflation/deflation cycle within Axial's summit caldera for the past 15 years. These data are now being supplemented by repeat bathymetric mapping by AUV. The long-term pattern appears to be "inflation predictable", in which eruptions are triggered at or near the same level of inflation. This pattern allowed us to successfully forecast in September 2014 that the next eruption was expected to occur at Axial sometime in 2015 (a 1-year time window). It is noteworthy that the rate of inflation between the 2011 and 2015 eruptions was about 4 times higher than between the 1998 and 2011 eruptions (60 cm/yr vs. 15 cm/yr). Subsidence at the caldera center began at 06:00 on 24 April (all times GMT) and amounted to 2.2 m by 02:00 on 25 April (20 hours in), 2.4 m by 00:00 on 28 April, and 2.45 m by 05 May when subsidence ended and re-inflation began (which has continued ever since). This amount of subsidence is similar to that observed during the 2011 eruption, but in 2015 the initial rate of subsidence was higher (11 cm/hr during the first 20 hours vs. 7 cm/hr in 2011) and the duration appears to have been longer (11 days vs. 6 days). Also, the 1998 and 2011 eruptions occurred along the southeastern edge of the caldera and along Axial's south rift zone, whereas the 2015 eruption occurred along the north rift zone (Kelley, AGU-2015). Here we present preliminary results of our August

  1. Modelling larval transport in a axial convergence front

    NASA Astrophysics Data System (ADS)

    Robins, P.

    2010-12-01

    Marine larvae exhibit different vertical swimming behaviours, synchronised by factors such as tidal currents and daylight, in order to aid retention near the parent populations and hence promote production, avoid predation, or to stimulate digestion. This paper explores two types of larval migration in an estuarine axial convergent front which is an important circulatory mechanism in many coastal regions where larvae are concentrated. A parallelised, three-dimensional, ocean model was applied to an idealised estuarine channel which was parameterised from observations of an axial convergent front which occurs in the Conwy Estuary, U.K. (Nunes and Simpson, 1985). The model successfully simulates the bilateral cross-sectional recirculation of an axial convergent front, which has been attributed to lateral density gradients established by the interaction of the lateral shear of the longitudinal currents with the axial salinity gradients. On the flood tide, there is surface axial convergence whereas on the ebb tide, there is (weaker) surface divergence. Further simulations with increased/decreased tidal velocities and with stronger/weaker axial salinity gradients are planned so that the effects of a changing climate on the secondary flow can be understood. Three-dimensional Lagrangian Particle Tracking Models (PTMs) have been developed which use the simulated velocity fields to track larvae in the estuarine channel. The PTMs take into account the vertical migrations of two shellfish species that are commonly found in the Conwy Estuary: (i) tidal migration of the common shore crab (Carcinus maenas) and (ii), diel (daily) migration of the Great scallop (Pecten maximus). These migration behaviours are perhaps the most widespread amongst shellfish larvae and have been compared with passive (drifting) particles in order to assess their relative importance in terms of larval transport. Preliminary results suggest that the net along-estuary dispersal over a typical larval

  2. Ultra-low dose CT attenuation correction for PET/CT

    NASA Astrophysics Data System (ADS)

    Xia, Ting; Alessio, Adam M.; De Man, Bruno; Manjeshwar, Ravindra; Asma, Evren; Kinahan, Paul E.

    2012-01-01

    A challenge for positron emission tomography/computed tomography (PET/CT) quantitation is patient respiratory motion, which can cause an underestimation of lesion activity uptake and an overestimation of lesion volume. Several respiratory motion correction methods benefit from longer duration CT scans that are phase matched with PET scans. However, even with the currently available, lowest dose CT techniques, extended duration cine CT scans impart a substantially high radiation dose. This study evaluates methods designed to reduce CT radiation dose in PET/CT scanning. We investigated selected combinations of dose reduced acquisition and noise suppression methods that take advantage of the reduced requirement of CT for PET attenuation correction (AC). These include reducing CT tube current, optimizing CT tube voltage, adding filtration, CT sinogram smoothing and clipping. We explored the impact of these methods on PET quantitation via simulations on different digital phantoms. CT tube current can be reduced much lower for AC than that in low dose CT protocols. Spectra that are higher energy and narrower are generally more dose efficient with respect to PET image quality. Sinogram smoothing could be used to compensate for the increased noise and artifacts at radiation dose reduced CT images, which allows for a further reduction of CT dose with no penalty for PET image quantitation. When CT is not used for diagnostic and anatomical localization purposes, we showed that ultra-low dose CT for PET/CT is feasible. The significant dose reduction strategies proposed here could enable respiratory motion compensation methods that require extended duration CT scans and reduce radiation exposure in general for all PET/CT imaging.

  3. CT-assisted agile manufacturing

    NASA Astrophysics Data System (ADS)

    Stanley, James H.; Yancey, Robert N.

    1996-11-01

    The next century will witness at least two great revolutions in the way goods are produced. First, workers will use the medium of virtual reality in all aspects of marketing, research, development, prototyping, manufacturing, sales and service. Second, market forces will drive manufacturing towards small-lot production and just-in-time delivery. Already, we can discern the merging of these megatrends into what some are calling agile manufacturing. Under this new paradigm, parts and processes will be designed and engineered within the mind of a computer, tooled and manufactured by the offspring of today's rapid prototyping equipment, and evaluated for performance and reliability by advanced nondestructive evaluation (NDE) techniques and sophisticated computational models. Computed tomography (CT) is the premier example of an NDE method suitable for future agile manufacturing activities. It is the only modality that provides convenient access to the full suite of engineering data that users will need to avail themselves of computer- aided design, computer-aided manufacturing, and computer- aided engineering capabilities, as well as newly emerging reverse engineering, rapid prototyping and solid freeform fabrication technologies. As such, CT is assured a central, utilitarian role in future industrial operations. An overview of this exciting future for industrial CT is presented.

  4. Attenuation-based estimation of patient size for the purpose of size specific dose estimation in CT. Part II. Implementation on abdomen and thorax phantoms using cross sectional CT images and scanned projection radiograph images

    SciTech Connect

    Wang Jia; Christner, Jodie A.; Duan Xinhui; Leng Shuai; Yu Lifeng; McCollough, Cynthia H.

    2012-11-15

    Purpose: To estimate attenuation using cross sectional CT images and scanned projection radiograph (SPR) images in a series of thorax and abdomen phantoms. Methods: Attenuation was quantified in terms of a water cylinder with cross sectional area of A{sub w} from both the CT and SPR images of abdomen and thorax phantoms, where A{sub w} is the area of a water cylinder that would absorb the same dose as the specified phantom. SPR and axial CT images were acquired using a dual-source CT scanner operated at 120 kV in single-source mode. To use the SPR image for estimating A{sub w}, the pixel values of a SPR image were calibrated to physical water attenuation using a series of water phantoms. A{sub w} and the corresponding diameter D{sub w} were calculated using the derived attenuation-based methods (from either CT or SPR image). A{sub w} was also calculated using only geometrical dimensions of the phantoms (anterior-posterior and lateral dimensions or cross sectional area). Results: For abdomen phantoms, the geometry-based and attenuation-based methods gave similar results for D{sub w}. Using only geometric parameters, an overestimation of D{sub w} ranging from 4.3% to 21.5% was found for thorax phantoms. Results for D{sub w} using the CT image and SPR based methods agreed with each other within 4% on average in both thorax and abdomen phantoms. Conclusions: Either the cross sectional CT or SPR images can be used to estimate patient attenuation in CT. Both are more accurate than use of only geometrical information for the task of quantifying patient attenuation. The SPR based method requires calibration of SPR pixel values to physical water attenuation and this calibration would be best performed by the scanner manufacturer.

  5. Bilateral macrodactyly of the hands and feet with post-axial involvement - a case report.

    PubMed

    Bhat, A K; Bhaskaranand, K; Kanna, R

    2005-12-01

    Macrodactyly is a rare congenital anomaly characterized by large digits. The usual involvement of macrodactyly is on the pre-axial side of the limb. There has been only one case report to date with involvement of both hands and feet in a child with post-axial upper limb involvement. We report an adult male who has macrodactyly of both hands and feet with post-axial involvement of both hands and pre and post- axial involvement of both feet.

  6. Third-order aberration analysis of an off-axial optical system

    NASA Astrophysics Data System (ADS)

    Wakazono, Tsuyoshi; Yatagai, Toyohiko; Araki, Keisuke

    2016-02-01

    The aberration theory applied to co-axial optical systems is extended to off-axial systems, for which third-order aberration coefficients are considered. The derived aberrations are analyzed using three-dimensional ray bundles, spot diagrams, and image charts, and classified in relation to the system symmetry. This theory is very useful for optical designers, allowing them to clarify the relationship between the structures of off-axial optical systems and the corresponding off-axial aberrations.

  7. WE-AB-BRA-12: Virtual Endoscope Tracking for Endoscopy-CT Image Registration

    SciTech Connect

    Ingram, W; Rao, A; Wendt, R; Court, L; Yang, J; Beadle, B

    2015-06-15

    Purpose: The use of endoscopy in radiotherapy will remain limited until we can register endoscopic video to CT using standard clinical equipment. In this phantom study we tested a registration method using virtual endoscopy to measure CT-space positions from endoscopic video. Methods: Our phantom is a contorted clay cylinder with 2-mm-diameter markers in the luminal surface. These markers are visible on both CT and endoscopic video. Virtual endoscope images were rendered from a polygonal mesh created by segmenting the phantom’s luminal surface on CT. We tested registration accuracy by tracking the endoscope’s 6-degree-of-freedom coordinates frame-to-frame in a video recorded as it moved through the phantom, and using these coordinates to measure CT-space positions of markers visible in the final frame. To track the endoscope we used the Nelder-Mead method to search for coordinates that render the virtual frame most similar to the next recorded frame. We measured the endoscope’s initial-frame coordinates using a set of visible markers, and for image similarity we used a combination of mutual information and gradient alignment. CT-space marker positions were measured by projecting their final-frame pixel addresses through the virtual endoscope to intersect with the mesh. Registration error was quantified as the distance between this intersection and the marker’s manually-selected CT-space position. Results: Tracking succeeded for 6 of 8 videos, for which the mean registration error was 4.8±3.5mm (24 measurements total). The mean error in the axial direction (3.1±3.3mm) was larger than in the sagittal or coronal directions (2.0±2.3mm, 1.7±1.6mm). In the other 2 videos, the virtual endoscope got stuck in a false minimum. Conclusion: Our method can successfully track the position and orientation of an endoscope, and it provides accurate spatial mapping from endoscopic video to CT. This method will serve as a foundation for an endoscopy-CT registration

  8. A phantom for testing of 4D-CT for radiotherapy of small lesions

    SciTech Connect

    Dunn, L.; Kron, T.; Taylor, M. L.; Callahan, J.; Franich, R. D.

    2012-09-15

    Purpose: The use of time-resolved four-dimensional computed tomography (4D-CT) in radiotherapy requires strict quality assurance to ensure the accuracy of motion management protocols. The aim of this work was to design and test a phantom capable of large amplitude motion for use in 4D-CT, with particular interest in small lesions typical for stereotactic body radiotherapy. Methods: The phantom of 'see-saw' design is light weight, capable of including various sample materials and compatible with several surrogate marker signal acquisition systems. It is constructed of polymethylmethacrylate (Perspex) and its movement is controlled via a dc motor and drive wheel. It was tested using two CT scanners with different 4D acquisition methods: the Philips Brilliance Big Bore CT (helical scan, pressure belt) and a General Electric Discovery STE PET/CT (axial scan, infrared marker). Amplitudes ranging from 1.5 to 6.0 cm and frequencies of up to 40 cycles per minute were used to study the effect of motion on image quality. Maximum intensity projections (MIPs), as well as average intensity projections (AIPs) of moving objects were investigated and their quality dependence on the number of phase reconstruction bins assessed. Results: CT number discrepancies between moving and stationary objects were found to have no systematic dependence on amplitude, frequency, or specific interphase variability. MIP-delineated amplitudes of motion were found to match physical phantom amplitudes to within 2 mm for all motion scenarios tested. Objects undergoing large amplitude motions (>3.0 cm) were shown to cause artefacts in MIP and AIP projections when ten phase bins were assigned. This problem can be mitigated by increasing the number of phase bins in a 4D-CT scan. Conclusions: The phantom was found to be a suitable tool for evaluating the image quality of 4D-CT motion management technology, as well as providing a quality assurance tool for intercenter/intervendor testing of commercial 4D-CT

  9. Masses and axial currents of the doubly charmed baryons

    NASA Astrophysics Data System (ADS)

    Sun, Zhi-Feng; Liu, Zhan-Wei; Liu, Xiang; Zhu, Shi-Lin

    2015-05-01

    The chiral dynamics of the doubly heavy baryons is solely governed by the light quark. In this paper, we have derived the chiral corrections to the mass of the doubly heavy baryons up to N3LO . The mass splitting of Ξc c and Ωc c at the N2LO depends on one unknown low energy constant c7. By fitting the lattice masses of Ξc c(3520 ), we estimate the mass of Ωc c to be around 3.726 GeV. Moreover, we have also performed a systematical analysis of the chiral corrections to the axial currents and axial charges of the doubly heavy baryons. The chiral structure and analytical expressions will be very useful to the chiral extrapolations of the future lattice QCD simulations of the doubly heavy baryons.

  10. Organocatalyzed Asymmetric Synthesis of Axially, Planar, and Helical Chiral Compounds.

    PubMed

    Shirakawa, Seiji; Liu, Shiyao; Kaneko, Shiho

    2016-02-04

    Axially, planar, and helical chiral compounds are indispensable building blocks in modern organic synthesis. A wide variety of chiral ligands and catalysts were designed based on these chiral scaffolds, and these chiral ligands and catalysts were used for various catalytic asymmetric transformations to produce important chiral compounds in an optically enriched form. Furthermore, these chiral skeletons are found in the structure of biologically active natural products. Thus, the development of efficient enantioselective methods for the synthesis of these chiral compounds is an important task in the field of organic chemistry. In the last few years, organocatalyzed approaches, which are one of the most reliable catalytic asymmetric methods, became a hot topic. This Focus Review summarizes asymmetric organocatalytic methods for the synthesis of axially, planar, and helical chiral compounds as useful chiral building blocks.

  11. [Inflammatory spinal diseases: axial spondyloarthritis : Central importance of imaging].

    PubMed

    Baraliakos, X; Fruth, M; Kiltz, U; Braun, J

    2017-03-01

    The diagnosis of axial spondyloarthritis (axSpA) includes classical ankylosing spondylitis (AS) as well as earlier stages and abortive courses of the disease, in which structural alterations have not yet occurred. These are classified as non-radiographic axSpA (nr-axSpa). Inflammatory changes in the entire axial skeleton are characteristic for axSpA and can be visualized by magnetic resonance imaging (MRI), while in most patients structural alterations, such as new bone formation with syndesmophytes and ankylosis develop in the later course of the disease. These bony alterations can best be visualized by conventional radiography and by computed tomography. Certain MRI sequences are nowadays considered as the standard method for depiction of inflammatory changes in axSpA. The introduction of MRI has led to a paradigm shift for this disease because the inflammatory lesions characteristic for the disease can be visualized at an early stage using appropriate MRI sequences.

  12. Axial transition form factors and pion decay of baryon resonances

    SciTech Connect

    Julia-Diaz, B.; Riska, D.O.; Coester, F.

    2004-10-01

    The pion decay constants of the lowest orbitally excited states of the nucleon and the {delta}(1232) along with the corresponding axial transition form factors are calculated with Poincare covariant constituent-quark models with instant, point, and front forms of relativistic kinematics. The model wave functions are chosen such that the calculated electromagnetic and axial form factors of the nucleon represent the empirical values in all three forms of kinematics, when calculated with single-constituent currents. The pion decay widths calculated with the three forms of kinematics are smaller than the empirical values. Front and instant form kinematics provide a similar description, with a slight preference for front form, while the point form values are significantly smaller in the case of the lowest positive parity resonances.

  13. Axial Torsion of Gangrenous Meckel's Diverticulum Causing Small Bowel Obstruction

    PubMed Central

    Sasikumar, K.; Noonavath, Ravinder Naik; Sreenath, G. S.; Maroju, Nanda Kishore

    2013-01-01

    Meckel's diverticulum (MD) is a commonly encountered congenital anomaly of the small intestine. We report an extremely unusual case of an axially torted, gangrenous MD presenting as acute intestinal obstruction. A 26-year-old male patient presented to our emergency department with 3 days history of abdominal pain, distention and bilious vomiting. On laparotomy, there was minimal hemorrhagic fluid localized in right iliac fossa and small bowel loops were dilated. A MD was seen attached to the mesentery of nonadjacent small bowel by a peritoneal band. The diverticulum was axially torted and gangrenous. In addition, there was compression of ileum by the peritoneal band resulting in intestinal obstruction, which was relieved on dividing the band. Resection and anastomosis of the small bowel including the MD was performed. We hereby report a rare and unusual complication of a MD. Although treatment outcome is generally good, pre-operative diagnosis is often difficult. PMID:24741431

  14. Buckling Imperfection Sensitivity of Axially Compressed Orthotropic Cylinders

    NASA Technical Reports Server (NTRS)

    Schultz, Marc R.; Nemeth, Michael P.

    2010-01-01

    Structural stability is a major consideration in the design of lightweight shell structures. However, the theoretical predictions of geometrically perfect structures often considerably over predict the buckling loads of inherently imperfect real structures. It is reasonably well understood how the shell geometry affects the imperfection sensitivity of axially compressed cylindrical shells; however, the effects of shell anisotropy on the imperfection sensitivity is less well understood. In the present paper, the development of an analytical model for assessing the imperfection sensitivity of axially compressed orthotropic cylinders is discussed. Results from the analytical model for four shell designs are compared with those from a general-purpose finite-element code, and good qualitative agreement is found. Reasons for discrepancies are discussed, and potential design implications of this line of research are discussed.

  15. Axially staged combustion system for a gas turbine engine

    DOEpatents

    Bland, Robert J.

    2009-12-15

    An axially staged combustion system is provided for a gas turbine engine comprising a main body structure having a plurality of first and second injectors. First structure provides fuel to at least one of the first injectors. The fuel provided to the one first injector is adapted to mix with air and ignite to produce a flame such that the flame associated with the one first injector defines a flame front having an average length when measured from a reference surface of the main body structure. Each of the second injectors comprising a section extending from the reference surface of the main body structure through the flame front and having a length greater than the average length of the flame front. Second structure provides fuel to at least one of the second injectors. The fuel passes through the one second injector and exits the one second injector at a location axially spaced from the flame front.

  16. Axially Tapered And Bilayer Microchannels For Evaporative Cooling Devices

    DOEpatents

    Nilson, Robert; Griffiths, Stewart

    2005-10-04

    The invention consists of an evaporative cooling device comprising one or more microchannels whose cross section is axially reduced to control the maximum capillary pressure differential between liquid and vapor phases. In one embodiment, the evaporation channels have a rectangular cross section that is reduced in width along a flow path. In another embodiment, channels of fixed width are patterned with an array of microfabricated post-like features such that the feature size and spacing are gradually reduced along the flow path. Other embodiments incorporate bilayer channels consisting of an upper cover plate having a pattern of slots or holes of axially decreasing size and a lower fluid flow layer having channel widths substantially greater than the characteristic microscale dimensions of the patterned cover plate. The small dimensions of the cover plate holes afford large capillary pressure differentials while the larger dimensions of the lower region reduce viscous flow resistance.

  17. Experimentally studying of axial compressor operation with steam

    NASA Astrophysics Data System (ADS)

    Batenin, V. M.; Zeigarnik, Yu. A.; Kosoi, A. S.; Datsenko, V. V.; Sinkevich, M. V.

    2015-12-01

    Steam offers numerous benefits when used as the working fluid in thermodynamic cycles. In lowtemperature cycles, where thermal energy is switched from one temperature potential to another (thermal transformers), steam is much less commonly used as a working fluid than in high-temperature cycles. The deficiencies of difficulties in using steam in thermal transformers include low pressure at the working temperatures and hence large specific volume. A compressor capable of high productivity having high discharge and relatively large increase in pressure is required. To that end, a multistage axial compressor from an airplane aircraft engine may be employed. To confirm the viability of this approach, the compressor of an AL-21 airplane aircraft engine is tested on a custom test bench. Experimental results are presented for a multistage axial compressor working with steam, when the input pressure is 0.5-5 kPa.

  18. Imaging in axial spondyloarthritis: diagnostic problems and pitfalls.

    PubMed

    Baraliakos, Xenofon; Hermann, Kay-Geert A; Braun, Jürgen

    2012-08-01

    Magnetic Structural changes in axial Spondyloarthritis (axSpA) are best identified by conventional radiographs, while magnetic resonance imaging (MRI) is considered the gold standard for assessment of inflammatory changes. Imaging of the axial skeleton is crucial for the diagnosis but also for classification to non-radiographic axSpA according to the 2009 ASAS classification criteria. Despite the existing definitions for a positive MRI for the sacroiliac joints and the spine, these predefined lesions can also be seen in other conditions, representing pitfalls and false-positive conclusions in patients with similar clinical symptoms who do not have SpA. Diagnosis of SpA should result from the combination of clinical, laboratory and imaging findings.

  19. Investigation of performance limits in axial groove heat pipes

    NASA Technical Reports Server (NTRS)

    Feldman, K. T.

    1976-01-01

    The entrainment-shear performance limit which occurs in axial groove heat pipes was investigated and explained. In the existing heat pipe literature the entrainment heat flux limit is defined as the condition where the Weber number is greater than or equal to one. In this analysis, the critical value for the entrainment Weber number is found to be 2 pi less than or equal to 3 pi. Perhaps more important to the heat pipe designer than the entrainment performance limit is the prediction of the performance degradation due to vapor-liquid shearing stress which is also described. Preliminary qualitative experiments were conducted to observe the shear. stress wave formation phenomena. The equations presented may be used to predict and minimize the vapor-liquid shear stress performance effects that occur in axial groove and puddle flow artery heat pipes.

  20. Axial Ge/Si nanowire heterostructure tunnel FETs

    SciTech Connect

    Picraux, Sanuel T; Daych, Shadi A

    2010-01-01

    The vapor-liquid-solid (VLS) growth of semiconductor nanowires allows doping and composition modulation along their axis and the realization of axial 1 D heterostructures. This provides additional flexibility in energy band-edge engineering along the transport direction which is difficult to attain by planar materials growth and processing techniques. We report here on the design, growth, fabrication, and characterization of asymmetric heterostructure tunnel field-effect transistors (HTFETs) based on 100% compositionally modulated Si/Ge axial NWs for high on-current operation and low ambipolar transport behavior. We discuss the optimization of band-offsets and Schottky barrier heights for high performance HTFETs and issues surrounding their experimental realization. Our HTFET devices with 10 nm PECVD SiN{sub x} gate dielectric resulted in a measured current drive exceeding 100 {mu}A/{mu}m (I/{pi}D) and 10{sup 5} I{sub on}/I{sub off} ratios.

  1. Reduced aniseikonia in axial anisometropia with contact lens correction.

    PubMed

    Winn, B; Ackerley, R G; Brown, C A; Murray, F K; Prais, J; St John, M F

    1988-01-01

    Aniseikonia, although present in isometropia, is associated principally with anisometropia and is widely thought to be the result of differences in the retinal image size presented to each eye. This assumes that equating retinal image size results in congruous cortical images. To test this assumption 1 refractive and 17 axial anisometropic subjects were examined to determine the aniseikonia present when corrected with spectacles and contact lenses. Contrary to many previous predictions, based upon Knapp's Law, the presence of equal retinal images resulted in larger aniseikonias than observed when the eyes were presented with unequal retinal images. This suggests that non-optical components have a significant role in the production of the cortical image, and this therefore requires a shift in the way the management of anisometropia is considered clinically. Contact lens correction maintains the aniseikonia at a minimum level in axial as well as refractive anisometropia and offers the clinician an acceptable practical alternative when prescribing for these patients.

  2. Inter- and Intra-Observer Reliability of Measurement of Pedicle Screw Breach Assessed by Postoperative CT Scans

    PubMed Central

    Ranade, Ashish; Samdani, Amer F.; Gaughan, John P.; D'Andrea, Linda P.; Betz, Randal R.

    2014-01-01

    Background Pedicle screws are used increasingly in spine surgery. Concerns of complications associated with screw breach necessitates accurate pedicle screw placement. Postoperative CT imaging helps to detect screw malposition and assess its severity. However, accuracy is dependent on the reading of the CT scans. Inter- and intra-observer variability could affect the reliability of CT scans to assess multiple screw types and sites. The purpose of this study was to assess the reliability of multi-observer analysis of CT scans for determining pedicle screw breach for various screw types and sites in patients with spinal deformity or degenerative pathologies. Methods Axial CT scan images of 23 patients (286 screws) were read by four experienced spine surgeons. Pedicle screw placement was considered 'In' when the screw was fully contained and/or the pedicle wall breach was ≤2 mm. 'Out' was defined as a breach in the medial or lateral pedicle wall >2 mm. Intra-class coefficients (ICC) were calculated to assess the inter- and intra-observer reliability. Results Marked inter- and intra-observer variability was noticed. The overall inter-observer ICC was 0.45 (95% confidence limits 0.25 to 0.65). The intra-observer ICC was 0.49 (95% confidence limits 0.29 to 0.69). Underlying spinal pathology, screw type, and patient age did not seem to impact the reliability of our CT assessments. Conclusion Our results indicate the evaluation of pedicle screw breach on CT by a single surgeon is highly variable, and care should be taken when using individual CT evaluations of millimeters of breach as a basis for screw removal. This was a Level III study. PMID:25694925

  3. Axial Seamount - Under the hood of the volcano machine.

    NASA Astrophysics Data System (ADS)

    Arnulf, A. F.; Harding, A. J.; Kent, G. M.

    2015-12-01

    On the Juan de Fuca ridge, Axial volcano is the most volcanically active site of the northwestern Pacific and it has been continuously monitored through two complete eruption cycles, with an increased number of seafloor instruments, leading in 2014 to the deployment of a permanent, wired-to-shore, seafloor observatory. Accurate imaging of the internal structure of volcanic systems is critical in order to characterize and quantify mass and energy transport mechanisms in such dynamic environments. To produce high-resolution velocity/reflectivity structures of Axial volcano, here, we combined a synthetic ocean bottom experiment (SOBE), 3-D traveltime tomography, 2D elastic full waveform and a reverse time migration (RTM) formalism.We present an updated and more complete outlook of Axial volcano upper crustal structure. We find that the addition of 469,891 traveltime arrivals, from twelve different multichannel seismic lines, to a previous OBSs-based traveltime tomography inversion, greatly improved the resolution of the three-dimensional velocity structure. We observe two elongated crustal magma reservoir beneath the central volcano. We investigate the extent, volume and physical state of those magma reservoirs and provide images of the volcanic plumbing system. We use our 3D velocity structure to relocate several months of seismicity and track magma movements between the caldera and the eruption site. We show that crustal-aging is controlled by pipe-like pattern of focused hydrothermal circulation. We suggest that the subsiding caldera floor at Axial Volcano was initiated ~720kyr +/-100kyr and provides a near perfect trap for the ponding of lava flows.

  4. Dynamic Buckling on Rectangular Plates under Axial Step Load

    NASA Astrophysics Data System (ADS)

    Diao, Bin-Bin; Han, Zhi-Jun; Lu, Guo-Yun

    2016-05-01

    Considering the effects of shear deformation and stress wave, the dynamic buckling governing equations of rectangular plates under axial step load are established. Based on the Rayleigh-Ritz method, the expression of the critical load is got. The relation curve between the critical load and critical length is described by using MATLAB software. In this paper, the influences of thickness, first-order shear deformation (FSD), and the number of modes are discussed.

  5. The Axial Compressive Strength of High Performance Polymer Fibers

    DTIC Science & Technology

    1985-03-01

    examined is a high-modulus graphite fiber (Union Carbide P-75) that is spun from mesophase pitch . This fiber is stretched during the graphitization...After approximately 3% axial compressive strain the fibers exhibited surface helical kink bands having a pitch angle of 600. Both left- and right-handed...strength using transmission optical microscopy with the beam bending technique. However, the compressive strengths of similar pitch -based graphite fibers

  6. Numerical Study of Axial Turbulent Flow Over Long Cylinders

    DTIC Science & Technology

    1992-04-01

    the planar case, with maxima (-21/2/u;t 3.2) also located at y+ 12. In a visualization study of axial flow over a cylinder, Lueptow & Haritonidis...a) I 0 0 50 100 150 200I + FIcuE 4.2 Profiles of the root-mean-square value of the pressure source terms normalized by v and Ur: (a) linear

  7. Rotary-To-Axial Motion Converter For Valve

    NASA Technical Reports Server (NTRS)

    Reinicke, Robert H.; Mohtar, Rafic

    1991-01-01

    Nearly frictionless mechanism converts rotary motion into axial motion. Designed for use in electronically variable pressure-regulator valve. Changes rotary motion imparted by motor into translation that opens and closes valve poppet. Cables spaced equidistantly around edge of fixed disk support movable disk. As movable disk rotated, cables twist, lifting it. When rotated in opposite direction, cables untwist, lowering it. Spider disk helps to prevent cables from tangling. Requires no lubrication and insensitive to contamination in fluid flowing through valve.

  8. Microwave axial free-electron laser with enhanced phase stability

    SciTech Connect

    Carlsten, B.; Fazio, M.; Haynes, W.

    1995-12-31

    Free-electron laser (FEL) amplifiers have demonstrated high efficiencies and high output power at microwave wavelengths. However, measurements and simulations have indicated that the present level of phase stability for these devices is not sufficient for driving linear accelerators. Fluctuations in the diode voltage, which is needed to accelerate the electron beam, are the largest cause of the shifts in the phase of the output power. Pulse-power technology cannot keep the voltage fluctuations less than 1/4%. However, we have found a scheme that will make the output phase much less sensitive to these fluctuations by exploiting the traveling wave nature of the FEL interaction. In this paper we study the phase stability issue by analyzing the dispersion relation for an axial FEL, in which the rf field is transversely wiggled and the electron trajectories are purely longitudinal. The advantage of using the axial FEL interaction instead of the common transverse FEL interaction is that (1) the dispersion relation is not additionally complicated by how the transverse electron motion depends on the diode voltage and (2) such a device is simpler and less expensive to construct than a transverse-coupling FEL because there is no wiggler. The axial FEL interaction is with a fast wave and does involve axial bunching of the electron beam, so the results found for this device also apply to transverse-coupling FELs. By examination of the dispersion relation it is found that the effect of the phase dependency on the beam`s velocity can be cancelled by the effect of the phase dependency on the beam`s plasma wave, for an annular electron beam. By changing the annulus radius, exact cancellation can be found for a variety of beam voltages and currents in the ranges of 0.5-1.0 MV and 1-5 kA. This cancellation leads to first-order phase stability, which is not possible for standing-wave devices, such as klystrons.

  9. Measurement of axial injection displacement with trim coil current unbalance

    SciTech Connect

    Covo, Michel Kireeff

    2014-08-15

    The Dee probe used for measuring internal radial beam intensity shows large losses inside the radius of 20 cm of the 88 in. cyclotron. The current of the top and bottom innermost trim coil 1 is unbalanced to study effects of the axial injection displacement. A beam profile monitor images the ion beam bunches, turn by turn. The experimental bunch center of mass position is compared with calculations of the magnetic mirror effect displacement and shows good agreement.

  10. Hypercapnia resulting from a faulty co-axial (Bain) circuit.

    PubMed

    Singh, Ishwar; Gupta, Monika; Singh, Tarun K

    2011-07-01

    The Bain co-axial circuit is fully established in general anaesthesia practice. A major concern is the potential malfunctioning of the circuit due to avulsion of the inner fresh gas delivery tube at the machine end of the circuit. The following case report presents a case in which a patient connected to the Bain circuit developed severe hypercapnia in the early intraoperative period due to the above mentioned defect.

  11. Enhanced betatron X-rays from axially modulated plasma wakefields

    SciTech Connect

    Palastro, J. P.; Kaganovich, D.; Gordon, D.

    2015-06-15

    In the cavitation regime of plasma-based accelerators, a population of high-energy electrons trailing the driver can undergo betatron motion. The motion results in X-ray emission, but the brilliance and photon energy are limited by the electrons' initial transverse coordinate. To overcome this, we exploit parametrically unstable betatron motion in a cavitated, axially modulated plasma. Theory and simulations are presented showing that the unstable oscillations increase both the total X-ray energy and average photon energy.

  12. Measurement of axial injection displacement with trim coil current unbalance

    NASA Astrophysics Data System (ADS)

    Covo, Michel Kireeff

    2014-08-01

    The Dee probe used for measuring internal radial beam intensity shows large losses inside the radius of 20 cm of the 88 in. cyclotron. The current of the top and bottom innermost trim coil 1 is unbalanced to study effects of the axial injection displacement. A beam profile monitor images the ion beam bunches, turn by turn. The experimental bunch center of mass position is compared with calculations of the magnetic mirror effect displacement and shows good agreement.

  13. Turbulence and Complex Flow Phenomena in Axial Turbomachines

    DTIC Science & Technology

    2007-11-02

    Adamczyk J. J., 1996, "Wake Mixing in Axial Flow Compressors," ASME Paper No. 96-GT-029 Adamczyk J.J., Mulac R.A., Celestina M.L., 1986, "A Model for...Closing the Inviscid Form of the Average-Passage Equation System," ASME Paper No. 86-GT-227 Adamczyk J.J.; Celestina M.L.; Beach T.A.; Barnett M., 1990

  14. Development of optimized, graded-permeability axial groove heat pipes

    NASA Technical Reports Server (NTRS)

    Kapolnek, Michael R.; Holmes, H. Rolland

    1988-01-01

    Heat pipe performance can usually be improved by uniformly varying or grading wick permeability from end to end. A unique and cost effective method for grading the permeability of an axial groove heat pipe is described - selective chemical etching of the pipe casing. This method was developed and demonstrated on a proof-of-concept test article. The process improved the test article's performance by 50 percent. Further improvement is possible through the use of optimally etched grooves.

  15. Small Laminated Axial Turbine Design and Test Program.

    DTIC Science & Technology

    1980-12-01

    the Disk Rim During Startup and Shutdown 112 74 CME Rotor Burst Ratio 114 75 PCM Laminate Tool No. 21 115 76 Small Cruise Missile Laminated Turbine 117...Jr., H. R. Fisk and J. A. Vonada, ’Demonstration of a Cooled Laminated Integral Axial Turbine," AIAA Paper 77-949. Reprinted in Journal of Aircraft... Tooling (PC0) for the small diameter laminated rotor. 3 4. .< ,.C, DESIGN ANALYSIS Heat-Ttansfer Performance Predictions The expected metal temperature

  16. Analysis of axial deformation response during reverse shear

    NASA Astrophysics Data System (ADS)

    Lowe, T. C.; Lipkin, J.

    T HE RESPONSE of a polycrystalline metal undergoing torsional shearing deformation is examined in detail using a strain-rate dependent model of the deformation of polycrystals. Several boundary value problems are solved to determine the roles of anisotropic elasticity and boundary constraints on the stresses and strains that develop along the torsion axis during forward and reverse shearing deformation. An initially random orientation distribution of 300 grains is assumed, and boundary conditions are chosen to represent a thin-walled tube with fixed, free and intermediate stiffness end constraints. A constant quasi-static shear strain rate of γ = 0.00775 s -1 is imposed to prestrain the polycrystal to a maximum shear strain γ = 1.6. At this point the sign of the shear strain rale is reversed and deformation is continued until the shear strain is reduced to essentially zero. For calculations in which some degree of axial constraint is imposed, the axial stress increases monotonically in compression during forward shearing. During reverse shearing, the axial stress response depends sensitively upon the degree of axial constraint, the textural anisotropy induced during forward shearing of the polycrystal. and the elastic anisotropy of the constituent grains. The model predictions demonstrate the role of anisotropic elasticity and the importance of minor strain components when modeling elastic plastic transients in textured polycrystals. Finally, the model predictions are compared with the results of experiments on short, thin-walled tubes of 304L stainless steel. Satisfactory agreement between a number of predicted and measured features of the response was obtained.

  17. Development of a Radiation Dose Reporting Software for X-ray Computed Tomography (CT)

    NASA Astrophysics Data System (ADS)

    Ding, Aiping

    X-ray computed tomography (CT) has experienced tremendous technological advances in recent years and has established itself as one of the most popular diagnostic imaging tools. While CT imaging clearly plays an invaluable role in modern medicine, its rapid adoption has resulted in a dramatic increase in the average medical radiation exposure to the worldwide and United States populations. Existing software tools for CT dose estimation and reporting are mostly based on patient phantoms that contain overly simplified anatomies insufficient in meeting the current and future needs. This dissertation describes the development of an easy-to-use software platform, “VirtualDose”, as a service to estimate and report the organ dose and effective dose values for patients undergoing the CT examinations. “VirtualDose” incorporates advanced models for the adult male and female, pregnant women, and children. To cover a large portion of the ignored obese patients that frequents the radiology clinics, a new set of obese male and female phantoms are also developed and applied to study the effects of the fat tissues on the CT radiation dose. Multi-detector CT scanners (MDCT) and clinical protocols, as well as the most recent effective dose algorithms from the International Commission on Radiological Protection (ICRP) Publication 103 are adopted in “VirtualDose” to keep pace with the MDCT development and regulatory requirements. A new MDCT scanner model with both body and head bowtie filter is developed to cover both the head and body scanning modes. This model was validated through the clinical measurements. A comprehensive slice-by-slice database is established by deriving the data from a larger number of single axial scans simulated on the patient phantoms using different CT bowtie filters, beam thicknesses, and different tube voltages in the Monte Carlo N-Particle Extended (MCNPX) code. When compared to the existing CT dose software packages, organ dose data in this

  18. Safety screw fixation technique in a case of coracoid base fracture with acromioclavicular dislocation and coracoid base cross-sectional size data from a computed axial tomography study.

    PubMed

    Kawasaki, Yoshiteru; Hirano, Tetsuya; Miyatake, Katsutoshi; Fujii, Koji; Takeda, Yoshitsugu

    2014-07-01

    Coracoid base fracture accompanied by acromioclavicular joint dislocation with intact coracoclavicular ligaments is a rare injury. Generally, an open reduction with screw fixation is the first treatment choice, as it protects the important structures around the coracoid process. This report presents a new technique of screw fixation for coracoid base fracture and provides anatomic information on cross-sectional size of the coracoid base obtained by computed tomography (CT). An axial image of the coracoid base was visualized over the neck of the scapula, and a guidewire was inserted into this circle under fluoroscopic guidance. The wire was inserted easily into the neck of scapula across the coracoid base fracture with imaging in only 1 plane. In addition, 25 measurements of the coracoid base were made in 25 subjects on axial CT images. Average length of the long and short axes at the thinnest part of the coracoid base was 13.9 ± 2.0 mm (range 10.6-17.0) and 10.5 ± 2.2 mm (6.6-15.1), respectively. This new screw fixation technique and measurement data on the coracoid base may be beneficial for safety screw fixation of coracoid base fracture.

  19. Can the nucleon axial charge be O(Nc0)?

    NASA Astrophysics Data System (ADS)

    Kojo, Toru

    2013-02-01

    The nucleon self-energy and its relation to the nucleon axial charge gA are discussed at large Nc. The energy is compared for the hedgehog, conventional, and recently proposed dichotomous nucleon wavefunctions which give different values for gA. We consider their energies at both perturbative and non-perturbative levels. In perturbative estimates, we take into account the pion exchanges among quarks up to the third orders of axial charge vertices, including the many-body forces such as the Wess-Zumino terms. It turns out that the perturbative pion exchanges among valence quarks give the same leading Nc contributions for three wavefunctions, while their mass differences are O(ΛQCD). The signs of splittings flip for different orders of the axial charge vertices, so it is hard to conclude which one is the most energetically favored. For non-perturbative estimates involving the modification of quark bases, we use the chiral quark soliton model as an illustration. With the hedgehog quark wavefunctions with gA of O(Nc), we investigate whether solutions with coherent pions are energetically favored. Again it is hard to give decisive conclusions, but it is possible that adding the confining effects disfavors the solution with the coherent pions, making a pion cloud around a nucleon quantum rather than coherent. The nuclear matter at large Nc is also discussed in light of the value of gA.

  20. A mini axial and a permanent maglev radial heart pump.

    PubMed

    Qian, Kun-Xi; Ru, Wei-Min; Wang, Hao; Jing, Teng

    2007-05-31

    The implantability and durability have been for decades the focus of artificial heart R&D. A mini axial and a maglev radial pump have been developed to meet with such requirements.The mini axial pump weighing 27g (incl.5g rotor) has an outer diameter of 21mm and a length of 10mm in its largest point, but can produce a maximal blood flow of 6l/min with 50mmHg pressure increase. Therefore, it is suitable for the patients of 40-60kg body weight. For other patients of 60-80kg or 80-100kg body weight, the mini axial pumps of 23mm and 25mm outer diameter had been developed before, these devices were acknowledged to be the world smallest LVADs by Guinness World Record Center in 2004.The permanent maglev radial pump weighing 150g is a shaft-less centrifugal pump with permanent magnetic bearings developed by the author. It needs no second coil for suspension of the rotor except the motor coil, different from all other maglev pumps developed in USA, Japan, European, etc. Thus no detecting and controlling systems as well as no additional power supply for maglev are necessary. The pump can produce a blood flow up to as large as 10l/min against 100mmHg pressure.An implantable and durable blood pump will be a viable alternative to natural donor heart for transplantation.

  1. The new performance calculation method of fouled axial flow compressor.

    PubMed

    Yang, Huadong; Xu, Hong

    2014-01-01

    Fouling is the most important performance degradation factor, so it is necessary to accurately predict the effect of fouling on engine performance. In the previous research, it is very difficult to accurately model the fouled axial flow compressor. This paper develops a new performance calculation method of fouled multistage axial flow compressor based on experiment result and operating data. For multistage compressor, the whole compressor is decomposed into two sections. The first section includes the first 50% stages which reflect the fouling level, and the second section includes the last 50% stages which are viewed as the clean stage because of less deposits. In this model, the performance of the first section is obtained by combining scaling law method and linear progression model with traditional stage stacking method; simultaneously ambient conditions and engine configurations are considered. On the other hand, the performance of the second section is calculated by averaged infinitesimal stage method which is based on Reynolds' law of similarity. Finally, the model is successfully applied to predict the 8-stage axial flow compressor and 16-stage LM2500-30 compressor. The change of thermodynamic parameters such as pressure ratio, efficiency with the operating time, and stage number is analyzed in detail.

  2. Whispering gallery resonators with broken axial symmetry: Theory and experiment.

    PubMed

    Fürst, J; Sturman, B; Buse, K; Breunig, I

    2016-09-05

    Axial symmetry is the cornerstone for theory and applications of high-Q optical whispering gallery resonators (WGRs). Nevertheless, research on birefringent crystalline material persistently pushes towards breaking this symmetry. We show theoretically and experimentally that the effect of broken axial symmetry, caused by optical anisotropy, is modest for the resonant frequencies and Q-factors of the WGR modes. Thus, the most important equatorial whispering gallery modes can be quantitatively described and experimentally identified. At the same time, the effect of broken axial symmetry on the light field distribution of the whispering gallery modes is typically very strong. This qualitatively modifies the phase-matching for the χ(2) nonlinear processes and enables broad-band second harmonic generation and optical parametric oscillation. The effect of weak geometric ellipticity in nominally symmetric WGRs is also considered. Altogether our findings pave the way for an extensive use of numerous birefringent (uniaxial and biaxial) crystals with broad transparency window and large χ(2) coefficients in nonlinear optics with WGRs.

  3. Axial length effects on lean NOx trap performance

    SciTech Connect

    Prikhodko, Vitaly Y; Nguyen, Ke; Choi, Jae-Soon; Daw, C Stuart

    2009-01-01

    The effect of axial length on the NO{sub x} reduction performance of two different commercial Lean NO{sub x} Trap (LNT) monolithic catalysts was experimentally investigated in a bench flow reactor. The washcoat composition of one of the catalysts consisted of Pt and K on {gamma}-Al{sub 2}O{sub 3}; whereas the other catalyst contained a complex mixture of Pt, Pd, Rh, Ba, Ce, Zr, Mg, Al and others. The NO{sub x} removal characteristics of cylindrical monolith segments of constant diameter (2.22 cm) and axial lengths of 2.54, 5.08 and 7.62 cm were evaluated using a simulated lean engine exhaust containing water and carbon dioxide at a constant space velocity of 30,000 h{sup -1}. No significant effects of length were observed when the catalysts were fully reduced with hydrogen between NO{sub x} capture phases. However when the catalysts were only partially regenerated NO{sub x} reduction efficiency increased with monolith length. Intra-catalyst H{sub 2} measurements at different axial locations indicated that at least some of the efficiency loss during partial regeneration occurred when back-mixed H{sub 2} was directly oxidized and became unavailable for nitrate reduction.

  4. The New Performance Calculation Method of Fouled Axial Flow Compressor

    PubMed Central

    Xu, Hong

    2014-01-01

    Fouling is the most important performance degradation factor, so it is necessary to accurately predict the effect of fouling on engine performance. In the previous research, it is very difficult to accurately model the fouled axial flow compressor. This paper develops a new performance calculation method of fouled multistage axial flow compressor based on experiment result and operating data. For multistage compressor, the whole compressor is decomposed into two sections. The first section includes the first 50% stages which reflect the fouling level, and the second section includes the last 50% stages which are viewed as the clean stage because of less deposits. In this model, the performance of the first section is obtained by combining scaling law method and linear progression model with traditional stage stacking method; simultaneously ambient conditions and engine configurations are considered. On the other hand, the performance of the second section is calculated by averaged infinitesimal stage method which is based on Reynolds' law of similarity. Finally, the model is successfully applied to predict the 8-stage axial flow compressor and 16-stage LM2500-30 compressor. The change of thermodynamic parameters such as pressure ratio, efficiency with the operating time, and stage number is analyzed in detail. PMID:25197717

  5. Period of vibration of axially vibrating truly nonlinear rod

    NASA Astrophysics Data System (ADS)

    Cveticanin, L.

    2016-07-01

    In this paper the axial vibration of a muscle whose fibers are parallel to the direction of muscle compression is investigated. The model is a clamped-free rod with a strongly nonlinear elastic property. Axial vibration is described by a nonlinear partial differential equation. A solution of the equation is constructed for special initial conditions by using the method of separation of variables. The partial differential equation is separated into two uncoupled strongly nonlinear second order differential equations. Both equations, with displacement function and with time function are exactly determined. Exact solutions are given in the form of inverse incomplete and inverse complete Beta function. Using boundary and initial conditions, the frequency of vibration is obtained. It has to be mentioned that the determined frequency represents the exact analytic description for the axially vibrating truly nonlinear clamped-free rod. The procedure suggested in this paper is applied for calculation of the frequency of the longissimus dorsi muscle of a cow. The influence of elasticity order and elasticity coefficient on the frequency property is tested.

  6. Axial stress localization facilitates pressure propagation in gelled pipes

    NASA Astrophysics Data System (ADS)

    Norrman, Jens; Skjæraasen, Olaf; Oschmann, Hans-Jörg; Paso, Kristofer; Sjöblom, Johan

    2016-03-01

    Paraffin wax-oil gels are unique rheological fluids which undergo shear degradation starting at a deformation (shear strain level) of approximately 1%. Flow commencement in pipelines filled with wax-oil gels is a complex hydrodynamic process involving propagation of acoustic, diffusive, and rheological degradation pressure wave fronts. Dynamic simulation informed by qualified rheological relations provides useful insight into the physical nature of these flow processes. Eulerian simulations are presented which emulate known physical phenomena and essential characteristics of wax-gel flow dynamics. A constitutive rheological equation set accounts for deformation-driven reduction in yield stress and viscosity terms. No explicit time-dependent rheological parameters are utilized in the equations. Rheological yielding alters the nature of the dominant pressure wave from inherently diffusive towards self-sharpening. Axial stress localization effectively sequentializes the gel breakage process, quantified by reduced length of the pressure wave-front zone. Ultimately, axial stress localization allows flow in longer pipe segments, albeit with a concomitant time delay. Viscous behavior and yielding degradation behavior are shown to account for upward and downward concavity in transient axial pressure profiles, respectively. Overall, a unique synergy between gel compressibility and gel degradation is revealed. Deformation-coupled interaction between compressibility and degradation allows pressure propagation and subsequent sustained flow through a gel material which is otherwise immobile in the incompressible case.

  7. ASAS classification criteria for axial spondyloarthritis: time to modify.

    PubMed

    Akkoc, Nurullah; Khan, Muhammad A

    2016-06-01

    The relationship between ankylosing spondylitis and the recently proposed entity called axial spondyloarthritis with its radiographic and non-radiographic forms that have been defined by the Assessment of Spondyloarthritis International Society (ASAS) criteria for axial spondyloarthritis (axSpA), is currently being debated. The Food and Drug Agency (FDA) had criticized the ASAS criteria and the studies which used these criteria to enroll patients in a clinical trial of certolizumab and adalimumab for the treatment of non-radiographic axial spondyloarthritis. The primary aim of classification criteria is to create homogenous patient populations for basic and clinical research. But the multi-arm construct of the ASAS criteria is a potential source of heterogeneity reducing their utility. Criteria sets should be regarded as dynamic concepts open to modifications or updates as our knowledge advances. We provide evidence to conclude that it is time to modify the ASAS Criteria for axSpA, and we propose some of the steps that can be taken to start moving forward in improving the validity of these criteria.

  8. Anterior axial ultrasound in monitoring infants with Pavlik harness.

    PubMed

    El Ferzli, Julie; Abuamara, Saad; Eurin, Danielle; Le Dosseur, Patrick; Dacher, Jean-Nicolas

    2004-01-01

    Real-time ultrasonography has been used for diagnosis and screening of developmental dysplasia of the hip for several years. If diagnostic criteria are well established, the use of sonography in follow-up of treated infants remains extremely variable. The aims of this study were (a). to describe the normal sonographic anatomy of the infant abducted hip on an anterior axial view, and (b). to define the role of this approach in the follow-up of developmental dysplasia treated by Pavlik harness. Thirty-eight patients with Pavlik harness had anterior axial sonograms in addition to their usual clinical and sonographic follow-up. Normal anatomy was inferred from the examination of 25 clinically proven normal hips in the same population. The best criterion of a normal positioning of the femoral head appears to be the alignment of the pubic bone and the femoral metaphysis. Pavlik harness was the only treatment in 32 patients. It was directly efficient in 22, after readjustment in 10 patients. Reduction was shown by anterior sonography in all of them. In 6 children, sonography showed no reduction and subsequent treatment by closed or open reduction was carried out. Anterior axial sonogram can show reduction of a dislocated hip in children with Pavlik harness, but it does not evaluate its stability. It helps optimize the settings of the harness, and may predict a poor outcome, but it does not identify the cause of non-reducibility.

  9. Aeroelastic flutter in axial flow-The continuum theory

    NASA Astrophysics Data System (ADS)

    Balakrishnan, A. V.; Tuffaha, A. M.

    2012-11-01

    We present a mathematical continuum model for aeroelastic flutter of a Goland type structure subject to axial airflow. The model consists of a linearized Euler full potential equation for the airflow and a second order linear structure equation in two degrees of freedom plunge and pitch (bending and torsion). These are coupled through velocity matching type conditions and Kutta type condition describing the pressure jump. The approach mimics the approach used to study aeroelastic flutter in the normal flow case [?], which deals with aircraft applications. We layout the theoretical framework for determining the aeroelastic modes and the flutter point of the structure at any given mode. We will focus on the torsion aeroelastic modes and consider bending modes in future work. The importance of studying aeroelastic flutter in the axial flow case has come to attention in the recent years in light of non aircraft applications of which we mention two: the problem of snoring or apnea, which can be characterized as palattal flutter and secondly power generation from structures placed in axial flow.

  10. Fundamental metallurgical aspects of axial splitting in zircaloy cladding

    SciTech Connect

    Chung, H. M.

    2000-04-03

    Fundamental metallurgical aspects of axial splitting in irradiated Zircaloy cladding have been investigated by microstructural characterization and analytical modeling, with emphasis on application of the results to understand high-burnup fuel failure under RIA situations. Optical microscopy, SEM, and TEM were conducted on BWR and PWR fuel cladding tubes that were irradiated to fluence levels of 3.3 x 10{sup 21} n cm{sup {minus}2} to 5.9 x 10{sup 21} n cm{sup {minus}2} (E > 1 MeV) and tested in hot cell at 292--325 C in Ar. The morphology, distribution, and habit planes of macroscopic and microscopic hydrides in as-irradiated and posttest cladding were determined by stereo-TEM. The type and magnitude of the residual stress produced in association with oxide-layer growth and dense hydride precipitation, and several synergistic factors that strongly influence axial-splitting behavior were analyzed. The results of the microstructural characterization and stress analyses were then correlated with axial-splitting behavior of high-burnup PWR cladding reported for simulated-RIA conditions. The effects of key test procedures and their implications for the interpretation of RIA test results are discussed.

  11. Axial and Centrifugal Compressor Mean Line Flow Analysis Method

    NASA Technical Reports Server (NTRS)

    Veres, Joseph P.

    2009-01-01

    This paper describes a method to estimate key aerodynamic parameters of single and multistage axial and centrifugal compressors. This mean-line compressor code COMDES provides the capability of sizing single and multistage compressors quickly during the conceptual design process. Based on the compressible fluid flow equations and the Euler equation, the code can estimate rotor inlet and exit blade angles when run in the design mode. The design point rotor efficiency and stator losses are inputs to the code, and are modeled at off design. When run in the off-design analysis mode, it can be used to generate performance maps based on simple models for losses due to rotor incidence and inlet guide vane reset angle. The code can provide an improved understanding of basic aerodynamic parameters such as diffusion factor, loading levels and incidence, when matching multistage compressor blade rows at design and at part-speed operation. Rotor loading levels and relative velocity ratio are correlated to the onset of compressor surge. NASA Stage 37 and the three-stage NASA 74-A axial compressors were analyzed and the results compared to test data. The code has been used to generate the performance map for the NASA 76-B three-stage axial compressor featuring variable geometry. The compressor stages were aerodynamically matched at off-design speeds by adjusting the variable inlet guide vane and variable stator geometry angles to control the rotor diffusion factor and incidence angles.

  12. CT of 338 active professional boxers.

    PubMed

    Jordan, B D; Jahre, C; Hauser, W A; Zimmerman, R D; Zarrelli, M; Lipsitz, E C; Johnson, V; Warren, R F; Tsairis, P; Folk, F S

    1992-11-01

    Computed tomography (CT) was performed in 338 active professional boxers. CT scans were abnormal in 25 boxers (7%). The most common CT abnormality was brain atrophy (22 cases). Focal lesions of low attenuation consistent with posttraumatic encephalomalacia were noted in only three boxers. Boxers with abnormal CT scans did not differ from those with borderline or normal CT scans in regard to age, win-loss record, number of bouts, or history of an abnormal electroencephalogram. Thirty-seven boxers with borderline CT scans (49%) and 17 with abnormal CT scans (68%) reported a previous technical knockout (TKO) or knockout (KO), compared with only 89 (37%) of the 238 boxers with normal CT scans (P < .01). Brain atrophy was noted more frequently in boxers with a large cavum septum pellucidum (CSP) than in those with a small or no CSP (P < .05). Boxers with abnormal or borderline CT scans who experienced a TKO or KO were slightly older than those with normal CT scans and a history of a TKO or KO (P < .05).

  13. Modern CT applications in veterinary medicine.

    PubMed

    Garland, Melissa R; Lawler, Leo P; Whitaker, Brent R; Walker, Ian D F; Corl, Frank M; Fishman, Elliot K

    2002-01-01

    Although computed tomography (CT) is used primarily for diagnosis in humans, it can also be used to diagnose disease in veterinary patients. CT and associated three-dimensional reconstruction have a role in diagnosis of a range of illnesses in a variety of animals. In a sea turtle with failure to thrive, CT showed a nodal mass in the chest, granulomas in the lungs, and a ball in the stomach. CT of a sea dragon with balance and movement problems showed absence of the swim bladder. In a sloth with failure to thrive, CT allowed diagnosis of a coin in the intestine. CT of a puffin with failure to thrive showed a mass in the chest, which was found to be a hematoma. In a smooth-sided toad whose head was tilted to one side and who was circling in that direction, CT showed partial destruction of the temporal bone. CT of a domestic cat with listlessness showed a mass with focal calcification, which proved to be a leiomyosarcoma. CT of a sea otter showed pectus excavatum, which is caused by the animal smashing oysters against its chest. In a Japanese koi with abdominal swelling, CT allowed diagnosis of a hepatoma.

  14. Estimation of axial curvature of anterior sclera: correlation between axial length and anterior scleral curvature as affected by angle kappa.

    PubMed

    Lee, Sang-Mok; Choi, Hyuk Jin; Choi, Heejin; Kim, Mee Kum; Wee, Won Ryang

    2016-10-07

    BACKGROUND: Though the development and fitting of scleral contact lenses are expanding steadily, there is no simple method to provide scleral metrics for scleral contact lens fitting yet. The aim of this study was to establish formulae for estimation of the axial radius of curvature (ARC) of the anterior sclera using ocular biometric parameters that can be easily obtained with conventional devices.

  15. Light fields with an axially expanded intensity distribution for stable three-dimensional optical trapping.

    PubMed

    Zwick, Susanne; Schaub, Christian; Haist, Tobias; Osten, Wolfgang

    2010-09-13

    We introduce a new kind of light field to improve and simplify the trapping process of axially displaced particles. To this end we employ a light field with an axially expanded intensity distribution, which at the same time enables stable axial trapping. We present simulations of the axial intensity distribution of the novel trapping field and first experimental results, which demonstrate the improvement of the reliability of the axial trapping process. The method can be used to automate trapping of particles that are located outside of the focal plane of the microscope.

  16. Axial psoriatic arthritis: an intriguing clinical entity or a subset of an intriguing disease?

    PubMed

    Lubrano, Ennio; Spadaro, Antonio

    2012-07-01

    This article summarizes the state of the art of axial involvement in psoriatic arthritis (axial PsA). The definition and measurement of axial disease in PsA still remain problematic, and this, in turn, could affect the best approach of recognition and treatment of this intriguing subset of the psoriatic disease. Axial PsA has been studied over the last few years looking at the difference in function and radiological finding compared to ankylosing spondylitis (AS), trying to differentiate it from a coincidental AS with psoriasis. Finally, this review has described the diagnosis and treatment of axial PsA reporting the data obtained from the literature.

  17. Completeness map evaluation demonstrated with candidate next-generation cardiac CT architectures

    SciTech Connect

    Liu Baodong; Bennett, James; Wang Ge; De Man, Bruno; Zeng Kai; Yin Zhye; Fitzgerald, Paul; Yu Hengyong

    2012-05-15

    Purpose: In this report, the authors introduce the general concept of the completeness map, as a means to evaluate the completeness of data acquired by a given CT system design (architecture and scan mode). They illustrate the utility of completeness map by applying the completeness map concept to a number of candidate CT system designs, as part of a study to advance the state-of-the-art in cardiac CT. Methods: In order to optimally reconstruct a point within a volume of interest (VOI), the Radon transform on all possible planes through that point should be measured. The authors quantified the extent to which this ideal condition is satisfied for the entire image volume. They first determined a Radon completeness number for each point in the VOI, as the percentage of possible planes that is actually measured. A completeness map is then defined as a 3D matrix of the completeness numbers for the entire VOI. The authors proposed algorithms to analyze the projection datasets in Radon space and compute the completeness number for a fixed point and apply these algorithms to various architectures and scan modes that they are evaluating. In this report, the authors consider four selected candidate architectures, operating with different scan modes, for a total of five system design alternatives. Each of these alternatives is evaluated using completeness map. Results: If the detector size and cone angle are large enough to cover the entire cardiac VOI, a single-source circular scan can have {>=}99% completeness over the entire VOI. However, only the central z-slice can be exactly reconstructed, which corresponds to 100% completeness. For a typical single-source architecture, if the detector is limited to an axial dimension of 40 mm, a helical scan needs about five rotations to form an exact reconstruction region covering the cardiac VOI, while a triple-source helical scan only requires two rotations, leading to a 2.5x improvement in temporal resolution. If the source and

  18. Functional Imaging: CT and MRI

    PubMed Central

    van Beek, Edwin JR; Hoffman, Eric A

    2008-01-01

    Synopsis Numerous imaging techniques permit evaluation of regional pulmonary function. Contrast-enhanced CT methods now allow assessment of vasculature and lung perfusion. Techniques using spirometric controlled MDCT allow for quantification of presence and distribution of parenchymal and airway pathology, Xenon gas can be employed to assess regional ventilation of the lungs and rapid bolus injections of iodinated contrast agent can provide quantitative measure of regional parenchymal perfusion. Advances in magnetic resonance imaging (MRI) of the lung include gadolinium-enhanced perfusion imaging and hyperpolarized helium imaging, which can allow imaging of pulmonary ventilation and .measurement of the size of emphysematous spaces. PMID:18267192

  19. Cortical Tremor (CT) with coincident orthostatic movements.

    PubMed

    Termsarasab, Pichet; Frucht, Steven J

    2015-01-01

    Cortical tremor (CT) is a form of cortical reflex myoclonus that can mimic essential tremor (ET). Clinical features that are helpful in distinguishing CT from ET are the irregular and jerky appearance of the movements. We report two patients with CT with coexisting orthostatic movements, either orthostatic tremor (OT) or myoclonus, who experienced functional improvement in both cortical myoclonus and orthostatic movements when treated with levetiracetam.

  20. Pediatric CT and radiation: our responsibility

    NASA Astrophysics Data System (ADS)

    Frush, Donald P.

    2009-02-01

    In order to discuss the cost-benefit ratio of CT examinations in children, one must be familiar with the reasons why CT can provide a high collective or individual dose. The reasons include increasing CT use as well as lack of attention to dose reduction strategies. While those have been substantial efforts for dose reduction, additional work is necessary to prevent unnecessary radiation exposure. This responsibility is shared between science and medicine, industry, regulatory agencies, and patients as well.

  1. Multimodal CT in stroke imaging: new concepts.

    PubMed

    Ledezma, Carlos J; Wintermark, Max

    2009-01-01

    A multimodal CT protocol provides a comprehensive noninvasive survey of acute stroke patients with accurate demonstration of the site of arterial occlusion and its hemodynamic tissue status. It combines widespread availability with the ability to provide functional characterization of cerebral ischemia, and could potentially allow more accurate selection of candidates for acute stroke reperfusion therapy. This article discusses the individual components of multimodal CT and addresses the potential role of a combined multimodal CT stroke protocol in acute stroke therapy.

  2. Radiation dose measurements in coronary CT angiography

    PubMed Central

    Sabarudin, Akmal; Sun, Zhonghua

    2013-01-01

    Coronary computed tomography (CT) angiography is associated with high radiation dose and this has raised serious concerns in the literature. Awareness of various parameters for dose estimates and measurements of coronary CT angiography plays an important role in increasing our understanding of the radiation exposure to patients, thus, contributing to the implementation of dose-saving strategies. This article provides an overview of the radiation dose quantity and its measurement during coronary CT angiography procedures. PMID:24392190

  3. Normal conus medullaris: CT criteria for recognition

    SciTech Connect

    Grogan, J.P.; Daniels, D.L.; Williams, I.L.; Rauschning, W.; Haughton, V.M.

    1984-06-01

    The normal CT configuration and dimension of the conus medullaris and adjacent spinal cord were determined in 30 patients who had no clinical evidence of conus compression. CT studies were also correlated with anatomic sections in cadavers. The normal conus on CT has a distinctive oval configuration, an arterior sulcus, and a posterior promontory. The anteroposterior diameter ranged from 5 to 8 mm; the transverse diameter from 8 to 11 mm. Intramedullary processes altered both the dimensions and configuration of the conus.

  4. The use of CT density changes at internal tissue interfaces to correlate internal organ motion with an external surrogate

    NASA Astrophysics Data System (ADS)

    Gaede, Stewart; Carnes, Gregory; Yu, Edward; Van Dyk, Jake; Battista, Jerry; Lee, Ting-Yim

    2009-01-01

    The purpose of this paper is to describe a non-invasive method to monitor the motion of internal organs affected by respiration without using external markers or spirometry, to test the correlation with external markers, and to calculate any time shift between the datasets. Ten lung cancer patients were CT scanned with a GE LightSpeed Plus 4-Slice CT scanner operating in a ciné mode. We retrospectively reconstructed the raw CT data to obtain consecutive 0.5 s reconstructions at 0.1 s intervals to increase image sampling. We defined regions of interest containing tissue interfaces, including tumour/lung interfaces that move due to breathing on multiple axial slices and measured the mean CT number versus respiratory phase. Tumour motion was directly correlated with external marker motion, acquired simultaneously, using the sample coefficient of determination, r2. Only three of the ten patients showed correlation higher than r2 = 0.80 between tumour motion and external marker position. However, after taking into account time shifts (ranging between 0 s and 0.4 s) between the two data sets, all ten patients showed correlation better than r2 = 0.8. This non-invasive method for monitoring the motion of internal organs is an effective tool that can assess the use of external markers for 4D-CT imaging and respiratory-gated radiotherapy on a patient-specific basis.

  5. Performance evaluation of a compact PET/SPECT/CT tri-modality system for small animal imaging applications

    NASA Astrophysics Data System (ADS)

    Wei, Qingyang; Wang, Shi; Ma, Tianyu; Wu, Jing; Liu, Hui; Xu, Tianpeng; Xia, Yan; Fan, Peng; Lyu, Zhenlei; Liu, Yaqiang

    2015-06-01

    PET, SPECT and CT imaging techniques are widely used in preclinical small animal imaging applications. In this paper, we present a compact small animal PET/SPECT/CT tri-modality system. A dual-functional, shared detector design is implemented which enables PET and SPECT imaging with a same LYSO ring detector. A multi-pinhole collimator is mounted on the system and inserted into the detector ring in SPECT imaging mode. A cone-beam CT consisting of a micro focus X-ray tube and a CMOS detector is implemented. The detailed design and the performance evaluations are reported in this paper. In PET imaging mode, the measured NEMA based spatial resolution is 2.12 mm (FWHM), and the sensitivity at the central field of view (CFOV) is 3.2%. The FOV size is 50 mm (∅)×100 mm (L). The SPECT has a spatial resolution of 1.32 mm (FWHM) and an average sensitivity of 0.031% at the center axial, and a 30 mm (∅)×90 mm (L) FOV. The CT spatial resolution is 8.32 lp/mm @10%MTF, and the contrast discrimination function value is 2.06% with 1.5 mm size cubic box object. In conclusion, a compact, tri-modality PET/SPECT/CT system was successfully built with low cost and high performance.

  6. Intracranial CT angiography obtained from a cerebral CT perfusion examination

    SciTech Connect

    Gratama van Andel, H. A. F.; Venema, H. W.; Majoie, C. B.; Den Heeten, G. J.; Grimbergen, C. A.; Streekstra, G. J.

    2009-04-15

    CT perfusion (CTP) examinations of the brain are performed increasingly for the evaluation of cerebral blood flow in patients with stroke and vasospasm after subarachnoid hemorrhage. Of the same patient often also a CT angiography (CTA) examination is performed. This study investigates the possibility to obtain CTA images from the CTP examination, thereby possibly obviating the CTA examination. This would save the patient exposure to radiation, contrast, and time. Each CTP frame is a CTA image with a varying amount of contrast enhancement and with high noise. To improve the contrast-to-noise ratio (CNR) we combined all 3D images into one 3D image after registration to correct for patient motion between time frames. Image combination consists of weighted averaging in which the weighting factor of each frame is proportional to the arterial contrast. It can be shown that the arterial CNR is maximized in this procedure. An additional advantage of the use of the time series of CTP images is that automatic differentiation between arteries and veins is possible. This feature was used to mask veins in the resulting 3D images to enhance visibility of arteries in maximum intensity projection (MIP) images. With a Philips Brilliance 64 CT scanner (64x0.625 mm) CTP examinations of eight patients were performed on 80 mm of brain using the toggling table technique. The CTP examination consisted of a time series of 15 3D images (2x64x0.625 mm; 80 kV; 150 mAs each) with an interval of 4 s. The authors measured the CNR in images obtained with weighted averaging, images obtained with plain averaging, and images with maximal arterial enhancement. The authors also compared CNR and quality of the images with that of regular CTA examinations and examined the effectiveness of automatic vein masking in MIP images. The CNR of the weighted averaged images is, on the average, 1.73 times the CNR of an image at maximal arterial enhancement in the CTP series, where the use of plain averaging

  7. Arterial wall perfusion measured with photon counting spectral x-ray CT

    NASA Astrophysics Data System (ADS)

    Jorgensen, Steven M.; Korinek, Mark J.; Vercnocke, Andrew J.; Anderson, Jill L.; Halaweish, Ahmed; Leng, Shuai; McCollough, Cynthia H.; Ritman, Erik L.

    2016-10-01

    Early atherosclerosis changes perfusion of the arterial wall due to localized proliferation of the vasa vasorum. When contrast agent passes through the artery, some enters the vasa vasorum and increases radiopacity of the arterial wall. Technical challenges to detecting changes in vasa vasorum density include the thin arterial wall, partial volume averaging at the arterial lumen/wall interface and calcification within the wall. We used a photon-counting spectral CT scanner to study carotid arteries of anesthetized pigs and micro-CT of these arteries to quantify vasa vasorum density. The left carotid artery wall was injected with autologous blood to stimulate vasa vasorum angiogenesis. The scans were performed at 25-120 keV; the tube-current-time product was 550 mAs. A 60 mL bolus of iodine contrast agent was injected into the femoral vein at 5mL/s. Two seconds post injection, an axial scan was acquired at every 3 s over 60 s (i.e., 20 time points). Each time point acquired 28 contiguous transaxial slices with reconstructed voxels 0.16 x 0.16 x 1 mm3. Regions-of-interest in the outer 2/3 of the arterial wall and in the middle 2/3 of the lumen were drawn and their enhancements plotted versus time. Lumenal CT values peaked several seconds after injection and then returned towards baseline. Arterial wall CT values peaked concurrent to the lumen. The peak arterial wall enhancement in the left carotid arterial wall correlated with increased vasa vasorum density observed in micro-CT images of the isolated arteries.

  8. Objective performance evaluation methods adapted to helical and multislice CT scanners

    NASA Astrophysics Data System (ADS)

    Ellerbusch, David C.

    Since its introduction in the early 1970's, Computed Tomography (CT) has evolved into an important imaging tool for a continually increasing variety of clinical applications. This growth is due to dramatic improvements in image quality and acquisition speed over the last sixteen years. These improvements have come from important technical developments that include sub-second gantry rotation times, helical scanning, multislice acquisition, and tube current modulation. The procedures for performing CT scanner evaluations have been in existence since the 1970's, but most are based on single-slice, axial scan geometry. These procedures are not adequate for the evaluation of modern, helical multislice scanners that use fundamentally different acquisition geometries, have many types of acquisition modes available, and are capable of generating huge numbers of images in a short period of time. Properly evaluating the image quality of these scanners is usually too difficult and time-consuming using the more traditional test methods. Computer analysis methods are needed to analyze the large number of images generated during a CT scanner evaluation. Subjecting these images to objective image evaluation methods will provide a much more thorough evaluation of image quality compared to subjective methods, and can do so in a shorter amount of time. This dissertation describes the development of objective analysis methods and improved phantom designs that more accurately and efficiently evaluate the image quality in helical multislice CT scanners. The new tools are appropriate for routine quality assurance, for acceptance testing of new equipment, and for optimizing techniques for novel clinical applications. Furthermore, using these methods we have found deficiencies and errors in the design of specific CT scanner models and also significant problems in the performance of individual scanner.

  9. Arterial Wall Perfusion Measured with Photon Counting Spectral X-ray CT

    PubMed Central

    Jorgensen, Steven M.; Korinek, Mark J.; Vercnocke, Andrew J.; Anderson, Jill L.; Halaweish, Ahmed; Leng, Shuai; McCollough, Cynthia H.; Ritman, Erik L.

    2016-01-01

    Early atherosclerosis changes perfusion of the arterial wall due to localized proliferation of the vasa vasorum. When contrast agent passes through the artery, some enters the vasa vasorum and increases radiopacity of the arterial wall. Technical challenges to detecting changes in vasa vasorum density include the thin arterial wall, partial volume averaging at the arterial lumen/wall interface and calcification within the wall. We used a photon-counting spectral CT scanner to study carotid arteries of anesthetized pigs and micro-CT of these arteries to quantify vasa vasorum density. The left carotid artery wall was injected with autologous blood to stimulate vasa vasorum angiogenesis. The scans were performed at 25–120 keV; the tube-current-time product was 550 mAs. A 60 mL bolus of iodine contrast agent was injected into the femoral vein at 5mL/s. Two seconds post injection, an axial scan was acquired at every 3 s over 60 s (i.e., 20 time points). Each time point acquired 28 contiguous transaxial slices with reconstructed voxels 0.16 × 0.16 × 1 mm3. Regions-of-interest in the outer 2/3 of the arterial wall and in the middle 2/3 of the lumen were drawn and their enhancements plotted versus time. Lumenal CT values peaked several seconds after injection and then returned towards baseline. Arterial wall CT values peaked concurrent to the lumen. The peak arterial wall enhancement in the left carotid arterial wall correlated with increased vasa vasorum density observed in micro-CT images of the isolated arteries. PMID:27807391

  10. Arterial Wall Perfusion Measured with Photon Counting Spectral X-ray CT.

    PubMed

    Jorgensen, Steven M; Korinek, Mark J; Vercnocke, Andrew J; Anderson, Jill L; Halaweish, Ahmed; Leng, Shuai; McCollough, Cynthia H; Ritman, Erik L

    2016-08-28

    Early atherosclerosis changes perfusion of the arterial wall due to localized proliferation of the vasa vasorum. When contrast agent passes through the artery, some enters the vasa vasorum and increases radiopacity of the arterial wall. Technical challenges to detecting changes in vasa vasorum density include the thin arterial wall, partial volume averaging at the arterial lumen/wall interface and calcification within the wall. We used a photon-counting spectral CT scanner to study carotid arteries of anesthetized pigs and micro-CT of these arteries to quantify vasa vasorum density. The left carotid artery wall was injected with autologous blood to stimulate vasa vasorum angiogenesis. The scans were performed at 25-120 keV; the tube-current-time product was 550 mAs. A 60 mL bolus of iodine contrast agent was injected into the femoral vein at 5mL/s. Two seconds post injection, an axial scan was acquired at every 3 s over 60 s (i.e., 20 time points). Each time point acquired 28 contiguous transaxial slices with reconstructed voxels 0.16 × 0.16 × 1 mm(3). Regions-of-interest in the outer 2/3 of the arterial wall and in the middle 2/3 of the lumen were drawn and their enhancements plotted versus time. Lumenal CT values peaked several seconds after injection and then returned towards baseline. Arterial wall CT values peaked concurrent to the lumen. The peak arterial wall enhancement in the left carotid arterial wall correlated with increased vasa vasorum density observed in micro-CT images of the isolated arteries.

  11. Crustal structure beneath the Kenya Rift from axial profile data

    USGS Publications Warehouse

    Mechie, J.; Keller, Gordon R.; Prodehl, C.; Gaciri, S.; Braile, L.W.; Mooney, W.D.; Gajewski, D.; Sandmeier, K.-J.

    1994-01-01

    Modelling of the KRISP 90 axial line data shows that major crustal thinning occurs along the axis of the Kenya Rift from Moho depths of 35 km in the south beneath the Kenya Dome in the vicinity of Lake Naivasha to 20 km in the north beneath Lake Turkana. Low Pn velocities of 7.5-7.7 km/s are found beneath the whole of the axial line. The results indicate that crustal extension increases to the north and that the low Pn velocities are probably caused by magma (partial melt) rising from below and being trapped in the uppermost kilometres of the mantle. Along the axial line, the rift infill consisting of volcanics and a minor amount of sediments varies in thickness from zero where Precambrian crystalline basement highs occur to 5-6 km beneath the lakes Turkana and Naivasha. Analysis of the Pg phase shows that the upper crystalline crust has velocities of 6.1-6.3 km/s. Bearing in mind the Cainozoic volcanism associated with the rift, these velocities most probably represent Precambrian basement intruded by small amounts of igneous material. The boundary between the upper and lower crusts occurs at about 10 km depth beneath the northern part of the rift and 15 km depth beneath the southern part of the rift. The upper part of the lower crust has velocities of 6.4-6.5 km/s. The basal crustal layer which varies in thickness from a maximum of 2 km in the north to around 9 km in the south has a velocity of about 6.8 km/s. ?? 1994.

  12. Volcanic inflation of Axial Seamount since the 1998 eruption

    NASA Astrophysics Data System (ADS)

    Nooner, S. L.; Chadwick, W.

    2010-12-01

    Since 2000, ambient seawater pressure has been precisely measured at five seafloor benchmarks inside the summit caldera at Axial Seamount in order to measure their relative depth and monitor volcanic inflation that has been occurring since an eruption in 1998. A remotely operated vehicle has been used to deploy a mobile pressure recorder (MPR) in campaign-style surveys, with additional seawater pressure data collected at the caldera center with multiyear deployments of continuously recording bottom pressure recorders (BPRs). Our previous measurements at Axial Seamount have shown steady inflation of the caldera center through 2007 and the spatial pattern of uplift has been consistent with magma storage in a shallow reservoir underlying the caldera at a depth of 3.5 km. This is the only location in the world where long-term monitoring of volcanic inflation has been accomplished at a submarine volcano. Here we present the results of new pressure data (both MPR and BPR) collected during a cruise on board the R/V Thomas Thompson in August-September 2010 and using the Jason ROV. Three years have passed since the previous survey, providing enough time to distinguish between two alternative models of inflation and magma recharge for the volcano. This allows us to refine our forecast for the next eruption at Axial and estimate total uplift that has occurred since the 1998 eruption. During the 2010 survey we also deployed new concrete benchmarks to replace our original galvanized steel benchmarks. The new benchmarks are larger and much heavier, and we expect them to be much more durable and stable over long time periods and help keep measurement errors as small as possible. We installed a sixth benchmark at a new site within the caldera, near the Ashes vent field, which will help constrain our modeling of the inflation signal in future years.

  13. Positional cloning of the gene for pre-axial polydactyly

    SciTech Connect

    Heutink, P.; Breedveld, G.J.; Zguricas, J.

    1994-09-01

    Pre-axial polydactyly can occur as an isolated anomaly, in association with other abnormalities of the hand or as a component of complex developmental disorders. We recently localized the gene for pre-axial polydactyly to the most distal part of chromosome 7q. Identification and characterization of the gene defect and studies of the expression pattern during embryonic development may help clarify questions about the role of this gene in other developmental processes than those in hands. A key element involved in the formation of the separate digits of the developing limb is the apical ectodermal ridge (AER). In the AER and in the adjacent mesoderm, homeobox genes as well as genes regulating programmed cell death, growth factors or receptors are expressed. Disruption of any of these genes might potentially interfere with normal differentiation. How these genes interact and which genes are involved in the formation of the five digits is still largely unknown. We have ascertained additional families and performed haplotype analysis to define the critical region. Currently, we are developing new STS polymorphic markers to narrow down this critical region. YAC and cosmid contigs are being developed. On the syntenic region of human 7q36, the mouse chromosome 5p, a mutation has been localized that resembles the human polydactyly phenotype. Hx is a candidate gene for the disease gene in the families studied. YACs from the critical regions of the human and mouse phenotypes are being used to identify conserved sequences. These sequences are used to isolate cDNAs which will be used for mutation analysis in human family material in order to isolate the responsible gene for pre-axial polydactyly. Our most recent results will be presented.

  14. Experimental and Numerical Investigation of an Axial Rotary Blood Pump.

    PubMed

    Schüle, Chan Yong; Thamsen, Bente; Blümel, Bastian; Lommel, Michael; Karakaya, Tamer; Paschereit, Christian Oliver; Affeld, Klaus; Kertzscher, Ulrich

    2016-04-18

    Left ventricular assist devices (LVADs) have become a standard therapy for patients with severe heart failure. As low blood trauma in LVADs is important for a good clinical outcome, the assessment of the fluid loads inside the pump is critical. More specifically, the flow features on the surfaces where the interaction between blood and artificial material happens is of great importance. Therefore, experimental data for the near-wall flows in an axial rotary blood pump were collected and directly compared to computational fluid dynamic results. For this, the flow fields based on unsteady Reynolds-averaged Navier-Stokes simulations-computational fluid dynamics (URANS-CFD) of an axial rotary blood pump were calculated and compared with experimental flow data at one typical state of operation in an enlarged model of the pump. The focus was set on the assessment of wall shear stresses (WSS) at the housing wall and rotor gap region by means of the wall-particle image velocimetry technique, and the visualization of near-wall flow structures on the inner pump surfaces by a paint erosion method. Additionally, maximum WSS and tip leakage volume flows were measured for 13 different states of operation. Good agreement between CFD and experimental data was found, which includes the location, magnitude, and direction of the maximum and minimum WSS and the presence of recirculation zones on the pump stators. The maximum WSS increased linearly with pressure head. They occurred at the upstream third of the impeller blades and exceeded the critical values with respect to hemolysis. Regions of very high shear stresses and recirculation zones could be identified and were in good agreement with simulations. URANS-CFD, which is often used for pump performance and blood damage prediction, seems to be, therefore, a valid tool for the assessment of flow fields in axial rotary blood pumps. The magnitude of maximum WSS could be confirmed and were in the order of several hundred Pascal.

  15. Mean Velocity of Local Populations: Axiality, Age and Time Dependence

    NASA Astrophysics Data System (ADS)

    Cubarsi, Rafael; Alcobé, Santiago

    2007-05-01

    The mean velocity of local stellar populations is analyzed by building a set of hierarchically selected samples from Hipparcos catalog, with the full space motions. The technique for scanning populations, MEMPHIS (Maximum Entropy of the Mixture Probability from HIerarchical Segregation), is a combination of two separate procedures: A sample selecting filter (Alcobé & Cubarsi 2005, A&A 442, 292) and a segregation method (Cubarsi & Alcobé 2004, A&A 427, 131). By continuously increasing the sampling parameter, in our case the absolute value of the stellar velocity, we build a set of nested subsamples containing an increasing number of populations. A bimodal pattern is then applied in order to identify differentiated kinematic populations. The resulting populations can be identified as early-type stars, young disk stars, old disk stars, and thick disk stars. Discontinuities of the velocity dispersion are found for early-type and thick disk stars, while young and old disk stars show a continuous trend that is asymptotically represented by the thin disk galactic component. Similarly, the mean velocity of early-type stars shows a particular behavior, while the remaining populations share a similar average motion. The later populations are studied on the basis of a time-dependent and non-axial Chandrasekhar model, allowing to estimate the degree of deviation from axial symmetry and steady-state hypotheses, as well as the average age of each population. According to this model, the no net radial movement point can be evaluated, having heliocentric velocities U=-18 ± 1 km/s in the radial direction, which is very close to the radial mean velocity of early-type stars, and V=-76 ± 2 km/s in rotation. The remaining populations share a common differential galactic movement, suggesting a common dynamical origin for the rupture of the axial symmetry.

  16. Particle classification in Taylor vortex flow with an axial flow

    NASA Astrophysics Data System (ADS)

    Ohmura, N.; Suemasu, T.; Asamura, Y.

    2005-01-01

    Particle classification phenomenon in Taylor vortex flow with an axial flow was investigated experimentally and numerically. The flow-visualization experiment by a laser-induced fluorescence method clearly revealed that there existed two distinct mixing regions at low Reynolds numbers. The tracer near the vortex cell boundary was rapidly transported axially owing to the bypass flow effect. On the other hand, the fluid element was confined to the vortex core region without being exchanged with the outer flow region. In order to observe particle classification phenomenon, polymethyl methacrylate (PMMA) particles suspended in the same aqueous solution of glycerol as the working fluid were fed into the top of the apparatus. Particle size was initially ranging from 10 to 80 µm. The ratio of the particle density to the fluid density was 1.04-1.05, which means the density difference between particle and fluid is very small. The suspended solution was withdrawn using a hypodermic needle every a certain time period at 30 mm above the bottom of apparatus. The fluid was sampled both near the outer wall and in vortex core. The particles sampled at 42 min having the size of 20-50 µm were mainly observed in the vortex core region. On the other hand, a large population of particles having the size of about 50-80 µm could be seen in the outer region of vortex. It was found that large particles located near the outer edge of vortices were quickly transported axially owing to the bypass flow effect. Numerical simulation also revealed that the loci of particles depended on the particle size.

  17. Mars - Change in axial tilt due to climate?

    NASA Technical Reports Server (NTRS)

    Rubincam, David Parry

    1990-01-01

    The average tilt of Mars' equator with respect to its orbital plane may have increased significantly over the age of the solar system. Obliquity oscillations might have induced changes in the climate, which altered the mass distribution and hence the solar torque on the planet. Viscous deformation attributable to loading by the large polar caps expected at low obliquity may have induced secular changes in the axial tilt. Earth-like effective viscosities can account for virtually the entire present obliquity of 24.4 degrees. Thus the present average tilt of Mars may not be primordial.

  18. Mars: change in axial tilt due to climate?

    PubMed

    Rubincam, D P

    1990-05-11

    The average tilt of Mars' equator with respect to its orbital plane may have increased significantly over the age of the solar system. Obliquity oscillations might have induced changes in the climate, which altered the mass distribution and hence the solar torque on the planet. Viscous deformation attributable to loading by the large polar caps expected at low obliquity may have induced secular changes in the axial tilt. Earth-like effective viscosities can account for virtually the entire present obliquity of 24.4 degrees. Thus the present average tilt of Mars may not be primordial.

  19. Parametric design of tri-axial nested Helmholtz coils

    SciTech Connect

    Abbott, Jake J.

    2015-05-15

    This paper provides an optimal parametric design for tri-axial nested Helmholtz coils, which are used to generate a uniform magnetic field with controllable magnitude and direction. Circular and square coils, both with square cross section, are considered. Practical considerations such as wire selection, wire-wrapping efficiency, wire bending radius, choice of power supply, and inductance and time response are included. Using the equations provided, a designer can quickly create an optimal set of custom coils to generate a specified field magnitude in the uniform-field region while maintaining specified accessibility to the central workspace. An example case study is included.

  20. Axially symmetric pulse propagation in semi-infinite hollow cylinders

    NASA Technical Reports Server (NTRS)

    Kohl, T.; Datta, S. K.; Shah, A. H.

    1992-01-01

    The effects of dispersion and end conditions on axially symmetric pulse propagation in semiinfinite tubes are investigated. Numerical modeling of the dynamic response is accomplished using a stable and efficient finite element and wave propagation based method. This method yields the dispersive and modal data required to express displacements in a frequency domain modal expansion. Boundary conditions are applied to the tube end to obtain mode amplitudes. A fast Fourier transform is then used to get the time response. The specific end conditions considered are intended to give some insight into how the tube would behave as a member of a jointed truss structure.

  1. Buckling of circular cylindrical shells under axial compression.

    NASA Technical Reports Server (NTRS)

    Budiansky, B.; Hutchinson, J. W.

    1972-01-01

    The infinitely long cylindrical shell under axial compression with axisymmetric sinusoidal imperfections is considered. The bifurcation problem is formulated exactly, and a complete family of buckling modes is identified. Koiter's (1963) upper bound pertains to the critical stress associated with one restricted set of modes, and the critical stress for a set of long wavelength modes reproduces some numerical results obtained by Almroth (1966). The initial postbuckling analysis is also formulated exactly. An exact analytical solution is obtained for the limiting case of modes with infinitely long wavelengths, and numerical analysis is used to solve the equations for the other cases. An appendix gives the details of the analysis.

  2. Discrimination of hydrogen-bonded complexes with axial chirality

    NASA Astrophysics Data System (ADS)

    Alkorta, Ibon; Elguero, José

    2002-10-01

    The chiral self-discrimination of twelve molecules showing axial chirality has been studied. They included peroxides, hydrazines, carboxylic acids, amides, and allenes. The homo and heterochiral dimers of the selected compounds, that present two hydrogen bonds, have been studied by means of density functional theory (B3LYP/6-31+G**) and ab initio (MP2/6-31+G** and MP2/6-311++G**) methods. The energetic differences found for the complexes of each compound have been rationalized based on their electron density maps and the natural bond orbital analysis. In some cases, intermolecular oxygen-oxygen interactions have been found and interpreted as additional stabilizing contacts.

  3. Parametric design of tri-axial nested Helmholtz coils.

    PubMed

    Abbott, Jake J

    2015-05-01

    This paper provides an optimal parametric design for tri-axial nested Helmholtz coils, which are used to generate a uniform magnetic field with controllable magnitude and direction. Circular and square coils, both with square cross section, are considered. Practical considerations such as wire selection, wire-wrapping efficiency, wire bending radius, choice of power supply, and inductance and time response are included. Using the equations provided, a designer can quickly create an optimal set of custom coils to generate a specified field magnitude in the uniform-field region while maintaining specified accessibility to the central workspace. An example case study is included.

  4. Rotor wake characteristics of a transonic axial flow fan

    NASA Technical Reports Server (NTRS)

    Hathaway, M. D.; Gertz, J.; Epstein, A.; Strazisar, A. J.

    1985-01-01

    State of the art turbomachinery flow analysis codes are not capable of predicting the viscous flow features within turbomachinery blade wakes. Until efficient 3D viscous flow analysis codes become a reality there is therefore a need for models which can describe the generation and transport of blade wakes and the mixing process within the wake. To address the need for experimental data to support the development of such models, high response pressure measurements and laser anemometer velocity measurements were obtained in the wake of a transonic axial flow fan rotor.

  5. Charged axially-symmetric solution in f( T) gravity theory

    NASA Astrophysics Data System (ADS)

    Nashed, G. G. L.

    2015-01-01

    In present article, an axially symmetric tetrad field has been applied to the charged field equations of f( T) gravity theory. Some constraints have been imposed to solve the resulting non-linear partial differential equations. An exact non-vacuum charged solution with three constants of integration is derived. The solution does not have non-trivial scalar torsion, T={T^i}_{jk}{S_i}^{jk}. Total conserved charges, using Poincaré gauge version, are calculated to understand the physical meaning of the three constants of integration. It has been shown that these constants are gravitational mass, angular momentum of the rotating source and charge parameter.

  6. Stability analysis of restricted non-static axial symmetry

    SciTech Connect

    Sharif, M.; Bhatti, M. Zaeem Ul Haq E-mail: mzaeem.math@gmail.com

    2013-11-01

    This paper aims to investigate the instability of very restricted class of non-static axially symmetric spacetime with anisotropic matter configuration. The perturbation scheme is established for the Einstein field equations and conservation laws. The instability range in the Newtonian and post-Newtonian regions are explored by constructing the collapse equation in this scenario. It is found that the adiabatic index plays an important role in the stability analysis which depends upon the physical parameters i.e., energy density and anisotropic pressure of the fluid distribution.

  7. Axial jet mixing of ethanol in spherical containers during weightlessness

    NASA Technical Reports Server (NTRS)

    Audelott, J. C.

    1976-01-01

    An experimental program was conducted to examine the liquid flow patterns that result from the axial jet mixing of ethanol in 10-centimeter-diameter spherical containers in weightlessness. Complete liquid circulation flow patterns were easily established in containers that were less than half full of liquid, while for higher liquid fill conditions, vapor was drawn into the inlet of the simulated mixer unit. Increasing the liquid-jet or lowering the position at which the liquid jet entered the container caused increasing turbulence and bubble formation.

  8. Axial jet mixing of ethanol in cylindrical containers during weightlessness

    NASA Technical Reports Server (NTRS)

    Aydelott, J. C.

    1979-01-01

    An experimental program was conducted to examine the liquid flow patterns that result from the axial jet mixing of ethanol in 10-centimeter-diameter cylindrical tanks in weightlessness. A convex hemispherically ended tank and two Centaur liquid-hydrogen-tank models were used for the study. Four distinct liquid flow patterns were observed to be a function of the tank geometry, the liquid-jet velocity, the volume of liquid in the tank, and the location of the tube from which the liquid jet exited.

  9. Buckling of circular cylindrical shells under dynamically applied axial loads

    NASA Technical Reports Server (NTRS)

    Tulk, J. D.

    1972-01-01

    A theoretical and experimental study was made of the buckling characteristics of perfect and imperfect circular cylindrical shells subjected to dynamic axial loading. Experimental data included dynamic buckling loads (124 data points), high speed photographs of buckling mode shapes and observations of the dynamic stability of shells subjected to rapidly applied sub-critical loads. A mathematical model was developed to describe the dynamic behavior of perfect and imperfect shells. This model was based on the Donnell-Von Karman compatibility and equilibrium equations and had a wall deflection function incorporating five separate modes of deflection. Close agreement between theory and experiment was found for both dynamic buckling strength and buckling mode shapes.

  10. Induced axial chirality in biocatalytic asymmetric ketone reduction.

    PubMed

    Agudo, Rubén; Roiban, Gheorghe-Doru; Reetz, Manfred T

    2013-02-06

    Catalytic asymmetric reduction of prochiral ketones of type 4-alkylidene cyclohexanone with formation of the corresponding axially chiral R-configurated alcohols (up to 99% ee) was achieved using alcohol dehydrogenases, whereas chiral transition-metal catalysts fail. Reversal of enantioselectivity proved to be possible by directed evolution based on saturation mutagenesis (up to 98% ee (S)). Utilization of ketone with a vinyl bromide moiety allows respective R- and S-alcohols to be exploited as key compounds in Pd-catalyzed cascade reactions.

  11. Method and apparatus for reducing axial thrust in centrifugal pumps

    NASA Astrophysics Data System (ADS)

    Palmer, Alan S.; Henry, John W., IV; Kerr, John P.

    1994-06-01

    A control stator comprising a plurality of stationary vanes, ribs, or cavities is provided in a centrifugal pump having a shrouded impeller. The function of the control stator is to slow the swirl of fluid in the cavity between the casing and the impeller front shroud and thereby provide a very cost effective solution to the problem of excess axial thrust. The control stator is a simple, inexpensive non-rotating part that can be affixed in an existing space in the pump casing between the casing wall and the front shroud of the impeller.

  12. Utility of the clivo-axial angle in assessing brainstem deformity: pilot study and literature review.

    PubMed

    Henderson, Fraser C; Henderson, Fraser C; Wilson, William A; Mark, Alexander S; Koby, Myles

    2017-03-03

    There is growing recognition of the kyphotic clivo-axial angle (CXA) as an index of risk of brainstem deformity and craniocervical instability. This review of literature and prospective pilot study is the first to address the potential correlation between correction of the pathological CXA and postoperative clinical outcome. The CXA is a useful sentinel to alert the radiologist and surgeon to the possibility of brainstem deformity or instability. Ten adult subjects with ventral brainstem compression, radiographically manifest as a kyphotic CXA, underwent correction of deformity (normalization of the CXA) prior to fusion and occipito-cervical stabilization. The subjects were assessed preoperatively and at one, three, six, and twelve months after surgery, using established clinical metrics: the visual analog pain scale (VAS), American Spinal InjuryAssociation Impairment Scale (ASIA), Oswestry Neck Disability Index, SF 36, and Karnofsky Index. Parametric and non-parametric statistical tests were performed to correlate clinical outcome with CXA. No major complications were observed. Two patients showed pedicle screws adjacent to but not deforming the vertebral artery on post-operative CT scan. All clinical metrics showed statistically significant improvement. Mean CXA was normalized from 135.8° to 163.7°. Correction of abnormal CXA correlated with statistically significant clinical improvement in this cohort of patients. The study supports the thesis that the CXA maybe an important metric for predicting the risk of brainstem and upper spinal cord deformation. Further study is feasible and warranted.

  13. Automated synthesis, insertion and detection of polyps for CT colonography

    NASA Astrophysics Data System (ADS)

    Sezille, Nicolas; Sadleir, Robert J. T.; Whelan, Paul F.

    2003-03-01

    CT Colonography (CTC) is a new non-invasive colon imaging technique which has the potential to replace conventional colonoscopy for colorectal cancer screening. A novel system which facilitates automated detection of colorectal polyps at CTC is introduced. As exhaustive testing of such a system using real patient data is not feasible, more complete testing is achieved through synthesis of artificial polyps and insertion into real datasets. The polyp insertion is semi-automatic: candidate points are manually selected using a custom GUI, suitable points are determined automatically from an analysis of the local neighborhood surrounding each of the candidate points. Local density and orientation information are used to generate polyps based on an elliptical model. Anomalies are identified from the modified dataset by analyzing the axial images. Detected anomalies are classified as potential polyps or natural features using 3D morphological techniques. The final results are flagged for review. The system was evaluated using 15 scenarios. The sensitivity of the system was found to be 65% with 34% false positive detections. Automated diagnosis at CTC is possible and thorough testing is facilitated by augmenting real patient data with computer generated polyps. Ultimately, automated diagnosis will enhance standard CTC and increase performance.

  14. Streak artifact reduction in cardiac cone beam CT

    NASA Astrophysics Data System (ADS)

    Shechter, Gilad; Naveh, Galit; Lessick, Jonathan; Altman, Ami

    2005-04-01

    Cone beam reconstructed cardiac CT images suffer from characteristic streak artifacts that affect the quality of coronary artery imaging. These artifacts arise from inhomogeneous distribution of noise. While in non-tagged reconstruction inhomogeneity of noise distribution is mainly due to anisotropy of the attenuation of the scanned object (e.g. shoulders), in cardiac imaging it is largely influenced by the non-uniform distribution of the acquired data used for reconstructing the heart at a given phase. We use a cardiac adaptive filter to reduce these streaks. In difference to previous methods of adaptive filtering that locally smooth data points on the basis of their attenuation values, our filter is applied as a function of the noise distribution of the data as it is used in the phase selective reconstruction. We have reconstructed trans-axial images without adaptive filtering, with a regular adaptive filter and with the cardiac adaptive filter. With the cardiac adaptive filter significant reduction of streaks is achieved, and thus image quality is improved. The coronary vessel is much more pronounced in the cardiac adaptive filtered images, in slab MIP the main coronary artery branches are more visible, and non-calcified plaque is better differentiated from vessel wall. This improvement is accomplished without altering significantly the border definition of calcified plaques.

  15. CT enterography with polyethylene glycol solution vs CT enteroclysis in small bowel disease

    PubMed Central

    Minordi, L M; Vecchioli, A; Mirk, P; Bonomo, L

    2011-01-01

    Objective The aim of the study is to compare CT enterography with polyethylene glycol solution (PEG-CT) with CT enteroclysis (CT-E) in patients with suspected small bowel disease. Methods 145 patients underwent abdominal contrast-enhanced 16-row multidetector CT after administration of 2000 ml of PEG by mouth (n = 75) or after administration of 2000 ml of methylcellulose by nasojejunal tube (n = 70). Small bowel distension, luminal and extraluminal findings were evaluated and compared with small bowel follow-through examination in 60 patients, double contrast enema in 50, surgery in 25 and endoscopy in 35. Statistical evaluation was carried out by χ2 testing. For both techniques we have also calculated the effective dose and the equivalent dose in a standard patient. Results Crohn's disease was diagnosed in 64 patients, neoplasms in 16, adhesions in 6. Distension of the jejunum was better with CT-E than PEG-CT (p<0.05: statistically significant difference). No significant difference was present for others sites (p>0.05). Evaluation of pathological ileal loops was good with both techniques. The values of sensitivity, specificity and diagnostic accuracy were respectively 94%, 100% and 96% with CT-E, and 93%, 94% and 93% with PEG-CT. The effective dose for PEG-CT was less than the dose for the CT-E (34.7 mSv vs 39.91 mSv). Conclusion PEG-CT shows findings of Crohn's disease as well as CT-E does, although CT-E gives better bowel distension, especially in the jejunum, and has higher specificity than PEG-CT. PMID:20959377

  16. SU-E-I-17: Evaluation of Commercially Available Extension Plates for the ACR CT Accreditation Phantom

    SciTech Connect

    Greene-Donnelly, K; Ogden, K

    2015-06-15

    Purpose: To evaluate the impact of commercially available extension plates on Hounsfield Unit (HU) values in the ACR CT accreditation phantom (Model 464, Gammex Inc., Middleton, Wi). The extension plates are intended to improve water HU values in scanners where the traditional solution involves scanning the phantom with an adjacent water or CTDI phantom. Methods: The Model 464 phantom was scanned on 9 different CT scanners at 8 separate sites representing 16 and 64 slice MDCT technology from four CT manufacturers. The phantom was scanned with and without the extension plates (Gammex 464 EXTPLT-KIT) in helical and axial modes. A water phantom was also scanned to verify water HU calibration. Technique was 120 kV tube potential, 350 mAs, and 210 mm display field of view. Slice thickness and reconstruction algorithm were based on site clinical protocols. The widest available beam collimation was used. Regions of interest were drawn on the HU test objects in Module 1 of the phantom and mean values recorded. Results: For all axial mode scans, water HU values were within limits with or without the extension plates. For two scanners (both Lightspeed VCT, GE Medical Systems, Waukesha WI), axial mode bone HU values were above the specified range both with and without the extension plates though they were closer to the specified range with the plates installed. In helical scan mode, two scanners (both GE Lightspeed VCT) had water HU values above the specified range without the plates installed. With the plates installed, the water HU values were within range for all scanners in all scan modes. Conclusion: Using the plates, the Lightspeed VCT scanners passed the water HU test when scanning in helical mode. The benefit of the extension plates was evident in helical mode scanning with GE scanners using a nominal 4 cm beam. Disclosure: The extension plates evaluated in this work were provided free of charge to the authors. The authors have no other financial interest in Gammex

  17. CT demonstration of bilateral adrenal hemorrhage

    SciTech Connect

    Ling, D.; Korobkin, M.; Silverman, P.M.; Dunnick, N.R.

    1983-08-01

    Bilateral adrenal hemorrhage with subsequent adrenal insufficiency is a recognized complication of anticoagulant therapy. Because the clinical manifestations are often nonspecific, the antemortem diagnosis of adrenal hemorrhage has been a difficult clinical problem. Computed tomography (CT) provides detailed images of the adrenal glands that are not possible with conventional imaging methods. The CT findings of bilateral adrenal hemorrhage in an anticoagulated patient are reported.

  18. Reconstructing misaligned x-ray CT data

    SciTech Connect

    Divin, C. J.

    2016-10-24

    Misalignment errors for x-ray computed tomography (CT) systems can manifest as artifacts and a loss of spatial and contrast resolution. To mitigate artifacts, significant effort is taken to determine the system geometry and minimizing any residual error in the system alignment. This project improved our ability to post-correct data which was acquired on a misaligned CT system.

  19. CT of schistosomal calcification of the intestine

    SciTech Connect

    Fataar, S.; Bassiony, H.; Satyanath, S.; Rudwan, M.; Hebbar, G.; Khalifa, A.; Cherian, M.J.

    1985-01-01

    The spectrum of schistosomal colonic calcification on abdominal radiographs has been described. The appearance on computed tomography (CT) is equally distinctive and occurs with varying degrees of genitourinary calcification. The authors have experience in three cases with the appearance on CT of intestinal calcification due to schistosomiasis.

  20. State-of-the-art in CT hardware and scan modes for cardiovascular CT

    PubMed Central

    Halliburton, Sandra; Arbab-Zadeh, Armin; Dey, Damini; Einstein, Andrew J.; Gentry, Ralph; George, Richard T.; Gerber, Thomas; Mahesh, Mahadevappa; Weigold, Wm. Guy

    2013-01-01

    Multidetector row computed tomography (CT) allows noninvasive anatomic and functional imaging of the heart, great vessels, and the coronary arteries. In recent years, there have been several advances in CT hardware, which have expanded the clinical utility of CT for cardiovascular imaging; such advances are ongoing. This review article from the Society of Cardiovascular Computed Tomography (SCCT) Basic and Emerging Sciences and Technology (BEST) Working Group summarizes the technical aspects of current state-of-the-art CT hardware and describes the scan modes this hardware supports for cardiovascular CT imaging. PMID:22551595

  1. State-of-the-art in CT hardware and scan modes for cardiovascular CT.

    PubMed

    Halliburton, Sandra; Arbab-Zadeh, Armin; Dey, Damini; Einstein, Andrew J; Gentry, Ralph; George, Richard T; Gerber, Thomas; Mahesh, Mahadevappa; Weigold, Wm Guy

    2012-01-01

    Multidetector row computed tomography (CT) allows noninvasive anatomic and functional imaging of the heart, great vessels, and coronary arteries. In recent years, there have been several advances in CT hardware, which have expanded the clinical utility of CT for cardiovascular imaging; such advances are ongoing. This review article from the Society of Cardiovascular Computed Tomography Basic and Emerging Sciences and Technology Working Group summarizes the technical aspects of current state-of-the-art CT hardware and describes the scan modes this hardware supports for cardiovascular CT imaging.

  2. The term 'non-radiographic axial spondyloarthritis' is much more important to classify than to diagnose patients with axial spondyloarthritis.

    PubMed

    Deodhar, Atul; Strand, Vibeke; Kay, Jonathan; Braun, Juergen

    2016-05-01

    The term axial spondyloarthritis (axSpA) now is used frequently to describe patients with predominantly axial symptoms who fit into the spectrum of a well-recognised rheumatic disease that continues to be known as ankylosing spondylitis (AS). The 2009 Assessment of SpondyloArthritis international Society (ASAS) classification criteria, developed to identify patients with early or atypical disease which could not be classified by the 1984 modified New York (mNY) criteria for AS, have led to a differentiation between non-radiographic axial spondyloarthritis (nr-axSpA) and radiographic axSpA, which is largely synonymous with AS. The main reason to distinguish between these ends of the spectrum of axSpA was that tumor necrosis factor (TNF) inhibitors (TNFi) approved for AS could obtain additional labelling for nr-axSpA and be used to treat all patients manifesting clinical features of axSpA. These two terms are distinguished by the degree of 'radiographic sacroiliitis' assessed by conventional radiography, according to the 1984 mNY criteria for AS. Since this differentiation has been shown to be not very reliable, we argue that the terms nr-axSpA and AS should only be used for classification of patients with axSpA and not as separate diagnoses. Therefore, we propose that only the term axSpA be used to diagnose patients, unless there is a meaningful medical reason to differentiate nr-axSpA from AS. The available data justify performing randomised controlled trials designed to obtain regulatory approval for therapeutic agents in patients across the entire spectrum of axSpA.

  3. Peripheral pulmonary arteries: identification at multi-slice spiral CT with 3D reconstruction.

    PubMed

    Coche, Emmanuel; Pawlak, Sebastien; Dechambre, Stéphane; Maldague, Baudouin

    2003-04-01

    Our objective was to analyze the peripheral pulmonary arteries using thin-collimation multi-slice spiral CT. Twenty consecutive patients underwent enhanced-spiral multi-slice CT using 1-mm collimation. Two observers analyzed the pulmonary arteries by consensus on a workstation. Each artery was identified on axial and 3D shaded-surface display reconstruction images. Each subsegmental artery was measured at a mediastinal window setting and compared with anatomical classifications. The location and branching of every subsegmental artery was recorded. The number of well-visualized sub-subsegmental arteries at a mediastinal window setting was compared with those visualized at a lung window setting. Of 800 subsegmental arteries, 769 (96%) were correctly visualized and 123 accessory subsegmental arteries were identified using the mediastinal window setting. One thousand ninety-two of 2019 sub-subsegmental arteries (54%) identified using the lung window setting were correctly visualized using the mediastinal window setting. Enhanced multi-slice spiral CT with thin collimation can be used to analyze precisely the subsegmental pulmonary arteries and may identify even more distal pulmonary arteries.

  4. CT-Guided Interventions Using a Free-Hand, Optical Tracking System: Initial Clinical Experience

    SciTech Connect

    Schubert, Tilman Jacob, Augustinus L.; Pansini, Michele; Liu, David; Gutzeit, Andreas; Kos, Sebastian

    2013-08-01

    PurposeThe present study was designed to evaluate the geometrical accuracy and clinical applicability of a new, free-hand, CT-guided, optical navigation system.MethodsFifteen procedures in 14 consecutive patients were retrospectively analyzed. The navigation system was applied for interventional procedures on small target lesions, in cases with long needle paths, narrow access windows, or when an out-of-plane access was expected. Mean lesion volume was 27.9 ml, and mean distance to target measured was 107.5 mm. Eleven of 15 needle trajectories were planned as out-of-plane approaches regarding the axial CT plane.ResultsNinety-one percent of the biopsies were diagnostic. All therapeutic interventions were technically successful. Targeting precision was high with a mean distance of the needle tip from planned target of 1.98 mm. Mean intervention time was 1:12 h. A statistically significant correlation between angular needle deviation and intervention time (p = 0.007), respiratory movement of the target (p = 0.008), and body mass index (p = 0.02) was detected. None of the evaluated parameters correlated significantly with the distance from the needle tip to the planned target.ConclusionsThe application of a navigation system for complex CT-guided procedures provided safe and effective targeting within a reasonable intervention time in our series.

  5. Non-local means resolution enhancement of lung 4D-CT data.

    PubMed

    Zhang, Yu; Wu, Guorong; Yap, Pew-Thian; Feng, Qianjin; Lian, Jun; Chen, Wufan; Shen, Dinggang

    2012-01-01

    Image resolution in 4D-CT is a crucial bottleneck that needs to be overcome for improved dose planning in radiotherapy for lung cancer. In this paper, we propose a novel patch-based algorithm to enhance the image quality of 4D-CT data. Our premise is that anatomical information missing in one phase can be recovered from complementary information embedded in other phases. We employ a patch-based mechanism to propagate information across phases for reconstruction of intermediate slices in the axial direction, where resolution is normally the lowest. Specifically, structurally-matching and spatially-nearby patches are combined for reconstruction of each patch. For greater sensitivity to anatomical nuances, we further employ a quad-tree technique to adaptively partition each slice of the image in each phase for more fine-grained refinement. Our evaluation based on a public 4D-CT lung data indicates that our algorithm gives very promising results with significantly enhanced image structures.

  6. Computational Study of Axial Fatigue for Peripheral Nitinol Stents

    NASA Astrophysics Data System (ADS)

    Meoli, Alessio; Dordoni, Elena; Petrini, Lorenza; Migliavacca, Francesco; Dubini, Gabriele; Pennati, Giancarlo

    2014-07-01

    Despite their success as primary treatment for vascular diseases, Nitinol peripheral stents are still affected by complications related to fatigue failure. Hip and knee movements during daily activities produce large and cyclic deformations of the superficial femoral artery, that concomitant to the effects of pulsatile blood pressure, may cause fatigue failure in the stent. Fatigue failure typically occurs in cases of very extended lesions, which often require the use of two or more overlapping stents. In this study, finite element models were used to study the fatigue behavior of Nitinol stents when subjected to cyclic axial compression in different conditions. A specific commercial Nitinol stent was chosen for the analysis and subjected to cyclic axial compression typical of the femoral vascular region. Three different configurations were investigated: stent alone, stent deployed in a tube, and two overlapping stents deployed in a tube. Results confirm that stent oversizing has an influence in determining both the mean and amplitude strains induced in the stent and plays an important role in determining the fatigue response of Nitinol stents. In case of overlapping stents, numerical results suggest higher amplitude strains concentrate in the region close to the overlapping portion where the abrupt change in stiffness causes higher cyclic compression. These findings help to explain the high incidence of stent fractures observed in various clinical trials located close to the overlapping portion.

  7. Four Centuries of the Geocentric Axial Dipole Hypothesis

    NASA Astrophysics Data System (ADS)

    Tauxe, L.; Kent, D. V.

    2004-12-01

    William Gilbert first articulated what has come to be known as the geocentric axial dipole hypothesis. The GAD hypothesis is the principle on which paleogeographic reconstructions rely to constrain paleolatitude. For decades there have been calls for permanent non-dipole contributions to the time averaged field. Recently, these have demanded large contributions of the axial octupole, which, if valid, would call into question the general utility of the GAD hypothesis. In the process of geological recording of the geomagnetic field, ``Earth filters'' distort the directions. Many processes, for example, sedimentary inclination error and random tilting lead to a net shallowing of the observed direction. Therefore inclinations that are shallower than expected from GAD can be explained by recording biases, northward transport, or non-dipole geomagnetic fields. Using paleomagnetic data from the last five million years from well constrained lava flow data allows the construction of a statistical geomagnetic field model. Such a model can predict not only the average expected direction for a given latitude, but also the shape of the distribution of directions produced by secular variation. This allows us to differentiate among the possible explanations for shallow bias. We find no compelling reason to abandon the geocentric dipole hypothesis that has served us well for four centuries.

  8. Ultrasonometry evaluation of axial compression osteosinthesis. An experimental study

    PubMed Central

    Bezuti, Márcio Takey; Mandarano, Luiz Garcia; Barbieri, Giuliano; Mazzer, Nilton; Barbieri, Cláudio Henrique

    2013-01-01

    OBJECTIVE: To measure the ultrasound propagation velocity (UV) through a tibial transverse osteotomy in sheep, before and after the fixation with a DCP plate. MATERIAL AND METHODS: Ten assemblies of a DCP plate with the diaphyseal segment of tibiae, in which a transverse osteotomy was made, were used. Both coronal and sagittal transverse and the axial UV were measured, first with the intact bone assembled with the plate and then with the uncompressed and compressed osteotomy; statistical comparisons were made at the 1% (p<0.01) level of significance. RESULTS: Compared with the intact bone assembly, axial UV significantly decreased with the addition of the osteotomy and significantly increased with compression, presenting the same behavior for the other modalities, although not significantly. DISCUSSION AND CONCLUSION: In accordance with the literature data on the ultrasonometric evaluation of fracture healing, underwater UV measurement was able to demonstrate the efficiency of DCP plate fixation. The authors conclude that the method has a potential for clinical application in the postoperative follow-up of DCP plate osteosinthesis, with a capability to demonstrate when it becomes ineffective. Laboratory investigation. PMID:24453644

  9. Sacroiliitis associated with axial spondyloarthropathy: new concepts and latest trends.

    PubMed

    Navallas, María; Ares, Jesús; Beltrán, Brigitte; Lisbona, María Pilar; Maymó, Joan; Solano, Albert

    2013-01-01

    The sacroiliac joints are involved in most cases of axial spondyloarthropathy, the first manifestation usually being sacroiliitis. A finding of sacroiliitis at radiography is the classic diagnostic hallmark of axial spondyloarthropathy. However, radiographic changes reflect structural damage rather than active inflammation, which may delay the diagnosis by several years. In the past decade, the field of spondyloarthropathy has undergone major changes, largely driven by the development of new drugs for the treatment of ankylosing spondylitis. In recent years, the Assessment of SpondyloArthritis international Society has focused on the reassessment of existing classification criteria and the development and validation of diagnostic tools to facilitate early diagnosis and assessment of treatment response. Magnetic resonance (MR) imaging is the most recent innovation and the important change with respect to the previously established classification criteria. This modality has become an integral part of managing patients with sacroiliitis. MR imaging can serve as a biomarker of disease activity, allows monitoring, and can provide guidance for the treatment of affected patients, and it will likely become even more central to the care of these patients. Familiarity with the anatomy, anatomic variants, and physiologic changes of the sacroiliac joints is important for correctly interpreting findings and avoiding misdiagnosis.

  10. Design and analysis of miniature tri-axial fluxgate magnetometer

    NASA Astrophysics Data System (ADS)

    Zhi, Menghui; Tang, Liang; Qiao, Donghai

    2017-02-01

    The detection technology of weak magnetic field is widely used in Earth resource survey and geomagnetic navigation. Useful magnetic field information can be obtained by processing and analyzing the measurement data from magnetic sensors. A miniature tri-axial fluxgate magnetometer is proposed in this paper. This miniature tri-axial fluxgate magnetometer with ring-core structure has a dynamic range of the Earth’s field ±65,000 nT, resolution of several nT. It has three independent parts placed in three perpendicular planes for measuring three orthogonal magnetic field components, respectively. A field-programmable gate array (FPGA) is used to generate stimulation signal, analog-to-digital (A/D) convertor control signal, and feedback digital-to-analog (D/A) control signal. Design and analysis details are given to improve the dynamic range, sensitivity, resolution, and linearity. Our prototype was measured and compared with a commercial standard Magson fluxgate magnetometer as a reference. The results show that our miniature fluxgate magnetometer can follow the Magson’s change trend well. When used as a magnetic compass, our prototype only has ± 0.3∘ deviation compared with standard magnetic compass.

  11. In vivo axial loading of the mouse tibia.

    PubMed

    Melville, Katherine M; Robling, Alexander G; van der Meulen, Marjolein C H

    2015-01-01

    Noninvasive methods to apply controlled, cyclic loads to the living skeleton are used as anabolic procedures to stimulate new bone formation in adults and enhance bone mass accrual in growing animals. These methods are also invaluable for understanding bone signaling pathways. Our focus here is on a particular loading model: in vivo axial compression of the mouse tibia. An advantage of loading the tibia is that changes are present in both the cancellous envelope of the proximal tibia and the cortical bone of the tibial diaphysis. To load the tibia of the mouse axially in vivo, a cyclic compressive load is applied up to five times a week to a single tibia per mouse for a duration lasting from 1 day to 6 weeks. With the contralateral limb as an internal control, the anabolic response of the skeleton to mechanical stimuli can be studied in a pairwise experimental design. Here, we describe the key parameters that must be considered before beginning an in vivo mouse tibial loading experiment, including methods for in vivo strain gauging of the tibial midshaft, and then we describe general methods for loading the mouse tibia for an experiment lasting multiple days.

  12. Simulation of the Galileo spacecraft axial - Delta-V algorithm

    NASA Technical Reports Server (NTRS)

    Longuski, J. M.

    1983-01-01

    Preliminary results are presented from the analysis of the Galileo spacecraft axial delta-V algorithm. The Galileo spacecraft is a dual spin interplanetary spacecraft which will study the four Galilean moons of Jupiter as well as the Jovian environment and atmosphere. In order to achieve orbit about Jupiter and accurately deliver the probe to the planet's upper atmosphere, the Galileo spacecraft must be capable of performing many trajectory corrections or delta-V maneuvers. Twelve 10 Newton thrusters and one 400 Newton engine are utilized for this purpose. There are many maneuver modes and control algorithms available to the spacecraft. In this paper only the analysis of the axial delta-V algorithm will be discussed. The analysis consists of two parts: an analytic study and a simulation study. The analytic results are based on rigid body dynamics, while the simulation includes the first order effect of the flexible magnetometer boom and nutation damper. The simulation utilizes a program developed at JPL which allows flexible body effects to be simulated by modeling a collection of rigid bodies attached together by hinges, springs and dampers. In this preliminary study of the Galileo only two rigid bodies were used in the simulation, but many more can and will be used in the final tests. In this analysis, the algorithm appears to be working correctly and the analytic and simulation results agree very well.

  13. Evanescent field shapes excitation profile under axial epi-illumination

    PubMed Central

    2012-01-01

    Abstract. Axial epi-illuminating light transmitting a >1.3-numerical-aperture microscope objective creates an excitation volume at focus with size and shape dictated by diffraction and due to refraction by the objective and by the coverslip interface separating a specimen in aqueous buffer from the oil immersion objective. The evanescent field on the coverslip aqueous side affects primarily the excitation volume axial dimension as the specimen in focus approaches the interface to within a few hundred nanometers. Following excitation, an excited stationary dipole moment emits fluorescence in a spatially varying pattern collected over the large objective aperture. Collected light propagates in parallel rays toward the tube lens that forms a real three-dimensional image that is decoded to identify dipole orientation. An integral representation of the excitation and emitted fields for infinity-corrected optics—including effects of finite conjugate illumination, fluorescence emission near an interface, emitter dipole orientation, spherical aberration, light transmission through a dichroic filter, and for real microscopic specifications—accurately models observed field intensities including the substantial excitation from the evanescent field. The goal is to develop and verify the practical depiction of excitation and emission in a real microscope for quantitative interpretation of the 3-D emission pattern. PMID:22734777

  14. Molecular dynamics study of nanojoining between axially positioned Ag nanowires

    NASA Astrophysics Data System (ADS)

    Cui, Jianlei; Theogene, Barayavuga; Wang, Xuewen; Mei, Xuesong; Wang, Wenjun; Wang, Kedian

    2016-08-01

    The miniaturization of electronics devices into nanometer scale is indispensable for next-generation semiconductor technology. Ag nanowires (Ag NWs) are considered to be the promising candidates for future electronic circuit owing to the excellent electrical and thermal properties. The nanojoining of axially positioned Ag NWs was performed by molecular dynamics simulation. Through the detailed atomic evolution during the nanojoining, the results indicate that the temperature and the distance between Ag NWs in axial direction have a great impact on nanojoining effect. When the nanojoining temperature is relatively high, the atoms are disordered and the atomic queues become to distort with strong thermodynamic properties and weak effect of metal bonds. At the relatively low temperature, the Ag NWs can be well connected with good junction quality and their own morphology, which is similar to the cold welding without fusion, while the distance between Ag NWs should be controlled for interaction and diffusion of interfacial atoms at nanowires head. When the Ag NWs are placed on Si and SiO2 substrate, because the atomic species and lattice structure of substrate material can differently affect the motions of Ag atoms through the interactive force between the atoms, the nanojoining quality of Ag NWs on Si substrate is better than that on the SiO2 substrate. So, for getting effective and reliable nanojoining without nanosolders and other materials, the temperature, distance and substrate surface should be reasonably controlled and selected, providing helpful theoretical guidance for experiment and application of nanojoining.

  15. Axial radiation asymmetry in dynamic hohlraums diagnosed spectro-scopically

    NASA Astrophysics Data System (ADS)

    Sanford, T. W. L.; Nash, T. J.; Mock, R. C.; Bailey, J. E.; Chandler, G. A.; Jobe, D. O.; Lake, P. W.; Leeper, R. J.; Lucas, J. M.; Mehlhorn, T. H.; Moore, T. C.; Nielson, D. S.; Apruzese, J. P.; Clark, R. W.; Kepple, P. C.; Davis, J.; Macfarlane, J. J.; Watt, R. C.; Peterson, D. L.; Chrien, R. E.; Idzorek, G. C.; Roderick, N. F.

    2003-10-01

    Dynamic-hohlraums (DH) driven by a Z pinch are being developed and used as intense blackbody x-ray sources for ICF and radiation-transport experiments. These sources have exhibited an unexpected axial asymmetry in their radiated power [1]. A new spectrometer system has been developed that enables the spectral emission to be measured exiting the bottom of the DH as well as the top. K-shell lines observed, with this system, mostly in absorption from Al and Mg tracer layers embedded within the DH are used to estimate the emission temperature at either end. Tungsten plasma, observed to prematurely slide across the bottom aperture, likely accounts for the bulk of the measured axial asymmetry. Possible models will be discussed. [1] T. W. L. Sanford, R. C. Mock, R. J. Leeper, D. L. Peterson, R. C. Watt, R. E. Chrien, G. C. Idzorek, B. V. Oliver, N. F. Roderick, and M. G. Haines, Phys.Plasmas 10, 1187 (2003). *Sandia is a multiprogram laboratory operated by the Sandia Corporation, a Lockheed Martin Company, for the U.S. Department of Energy under Contract No. DE-AC04-94AL85000.

  16. Axial tubule junctions control rapid calcium signaling in atria

    PubMed Central

    Brandenburg, Sören; Kohl, Tobias; Williams, George S.B.; Rog-Zielinska, Eva A.; Hebisch, Elke; Dura, Miroslav; Didié, Michael; Nikolaev, Viacheslav O.; Hasenfuss, Gerd; Kohl, Peter; Ward, Christopher W.; Lehnart, Stephan E.

    2016-01-01

    The canonical atrial myocyte (AM) is characterized by sparse transverse tubule (TT) invaginations and slow intracellular Ca2+ propagation but exhibits rapid contractile activation that is susceptible to loss of function during hypertrophic remodeling. Here, we have identified a membrane structure and Ca2+-signaling complex that may enhance the speed of atrial contraction independently of phospholamban regulation. This axial couplon was observed in human and mouse atria and is composed of voluminous axial tubules (ATs) with extensive junctions to the sarcoplasmic reticulum (SR) that include ryanodine receptor 2 (RyR2) clusters. In mouse AM, AT structures triggered Ca2+ release from the SR approximately 2 times faster at the AM center than at the surface. Rapid Ca2+ release correlated with colocalization of highly phosphorylated RyR2 clusters at AT-SR junctions and earlier, more rapid shortening of central sarcomeres. In contrast, mice expressing phosphorylation-incompetent RyR2 displayed depressed AM sarcomere shortening and reduced in vivo atrial contractile function. Moreover, left atrial hypertrophy led to AT proliferation, with a marked increase in the highly phosphorylated RyR2-pS2808 cluster fraction, thereby maintaining cytosolic Ca2+ signaling despite decreases in RyR2 cluster density and RyR2 protein expression. AT couplon “super-hubs” thus underlie faster excitation-contraction coupling in health as well as hypertrophic compensatory adaptation and represent a structural and metabolic mechanism that may contribute to contractile dysfunction and arrhythmias. PMID:27643434

  17. Preparation of microbubble suspensions by co-axial electrohydrodynamic atomization.

    PubMed

    Farook, U; Zhang, H B; Edirisinghe, M J; Stride, E; Saffari, N

    2007-09-01

    In this paper we report a novel method, based on co-axial electrohydrodynamic jetting, for the preparation of microbubble suspensions containing bubbles <10 microm in size and having a narrow size distribution. No selective filtration is necessary and the suspensions are produced directly by the process. To demonstrate the method, glycerol was used as the liquid medium, flowing in the outer needle of the co-axial twin needle arrangement and undergoing electrohydrodynamic atomization in the stable cone-jet mode while air flowed through the inner needle at the same time. At zero applied voltage a hollow stream of liquid flowed from the outer needle. When the applied voltage was increased, eventually the hollow stream became a stable cone-jet and emitted a microthread of bubbles, which were collected in a container of glycerol to obtain microbubble suspensions. The size of the microbubbles was measured via optical microscopy and laser diffractometry. Several microbubble suspensions were prepared and characterised and the size distribution was found to be critically dependent on the ratio (n) of flow rates of liquid/air and, in particular the flow rate of the air. At n=1.5, with the flow rate of air set at approximately 1.7 microl/s, a microbubble suspension containing bubbles in the size range 2-8 microm was obtained.

  18. Tgif1 and Tgif2 Regulate Axial Patterning in Mouse

    PubMed Central

    Wotton, David

    2016-01-01

    Tgif1 and Tgif2 are transcriptional repressors that inhibit the transcriptional response to transforming growth factor β signaling, and can repress gene expression by direct binding to DNA. Loss of function mutations in TGIF1 are associated with holoprosencephaly (HPE) in humans. In mice, embryos lacking both Tgif1 and Tgif2 fail to complete gastrulation, and conditional double null embryos that survive past gastrulation have HPE and do not survive past mid-gestation. Here we show that in mice of a relatively pure C57BL/6 strain background, loss of Tgif1 alone results in defective axial patterning and altered expression of Hoxc6. The primary defects in Tgif1 null embryos are the presence of extra ribs on the C7 vertebra, consistent with a posterior transformation phenotype. In addition we observed defective cervical vertebrae, primarily C1-C5, in both adult mice and embryos that lacked Tgif1. The combination of Tgif1 and Tgif2 mutations increases the severity and penetrance of the posterior transformation phenotype, without altering the type of defects seen. Similarly, exposure of Tgif1 mutant embryos to retinoic acid at E8.5 increased the severity and penetrance of the Tgif1 phenotype. This suggests that Tgif1 and Tgif2 regulate axial patterning and that reduced TGIF function sensitizes embryos to the effects of retinoic acid. PMID:27187787

  19. Development of a miniature intraventricular axial flow blood pump.

    PubMed

    Yamazaki, K; Umezu, M; Koyanagi, H; Outa, E; Ogino, S; Otake, Y; Shiozaki, H; Fujimoto, T; Tagusari, O; Kitamura, M

    1993-01-01

    A new intraventricular axial flow blood pump has been designed and developed as a totally implantable left ventricular assist device (LVAD). This pump consists of an impeller combined with a guide-vane, a tube housing, and a DC motor. The pump is introduced into the LV cavity through the LV apex, and the outlet cannula is passed antegrade across the aortic valve. Blood is withdrawn from the LV through the inlet ports at the pump base, and discharged to the ascending aorta. Our newly developed axial flow pump system has the following advantages: 1) it is a simple and compact system, 2) minimal blood stasis both in the device and the LV cavity, 3) minimal blood contacting surface of the pump, 4) easy accessibility with a less invasive surgical procedure, and 5) low cost. A pump flow > 5 L/min was obtained against 100 mmHg differential pressure in the mock circulatory system. The pump could produce a passive pulsatile flow effect with a beating heart more efficiently than other non-pulsatile pumps because of minimal pressure drop and inertia along the bypass tract. Anatomic fit studies using dissected hearts of dilated cardiomyopathy (DCM) cadavers showed that this pump could smoothly pass through the aortic valve without any interference with mitral valve function. Recently, a dynamic pressure groove bearing and a miniature lip seal have been developed. The dynamic pressure groove bearing has a simple structure and acts as a pressure resistant sealing mechanism.(ABSTRACT TRUNCATED AT 250 WORDS)

  20. Axial couplings and strong decay widths of heavy hadrons.

    PubMed

    Detmold, William; Lin, C-J David; Meinel, Stefan

    2012-04-27

    We calculate the axial couplings of mesons and baryons containing a heavy quark in the static limit using lattice QCD. These couplings determine the leading interactions in heavy hadron chiral perturbation theory and are central quantities in heavy quark physics, as they control strong decay widths and the light quark mass dependence of heavy hadron observables. Our analysis makes use of lattice data at six different pion masses, 227 MeVaxial couplings are g(1)=0.449(51), g(2)=0.84(20), and g(3)=0.71(13), where g(1) governs the interaction between heavy-light mesons and pions and g(2,3) are similar couplings between heavy-light baryons and pions. Using our lattice result for g(3), and constraining 1/m(Q) corrections in the strong decay widths with experimental data for Σ(c)(*) decays, we obtain Γ[Σ(b)(*)→Λ(b)π(±)]=4.2(1.0), 4.8(1.1), 7.3(1.6), 7.8(1.8) MeV for the Σ(b)(+), Σ(b)(-), Σ(b)(*+), Σ(b)(*-) initial states, respectively. We also derive upper bounds on the widths of the Ξ(b)(I(*)) baryons.