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Sample records for edwards mira bileaflet

  1. Wonderful Mira.

    PubMed

    Wareing, Christopher John

    2008-12-13

    Since being named 'wonderful' in the seventeenth century for its peculiar brightness variability, Mira A has been the subject of extensive research and become the prototype for a whole class of 'Mira' variable stars. The primary star in a binary system, Mira A is reaching the end of its life and currently undergoing an extended period of enhanced mass loss. Recent observations have revealed a surrounding arc-like structure and a stream of material stretching 12 light years away in opposition to the arc. In this article, I review recent modelling of this cometary appearance as a bow shock with an accompanying tail of material ram pressure stripped from the head of the bow shock, place Mira in an evolutionary context, predict its future with reference to the similar star R Hya and planetary nebula Sh 2-188, and speculate some avenues of research both on Mira itself and on other 'Mira-like' stars with bow shocks and tails. I also discuss the implications of this discovery for our own star, the Sun. PMID:18812301

  2. Wonderful Mira.

    PubMed

    Wareing, Christopher John

    2008-12-13

    Since being named 'wonderful' in the seventeenth century for its peculiar brightness variability, Mira A has been the subject of extensive research and become the prototype for a whole class of 'Mira' variable stars. The primary star in a binary system, Mira A is reaching the end of its life and currently undergoing an extended period of enhanced mass loss. Recent observations have revealed a surrounding arc-like structure and a stream of material stretching 12 light years away in opposition to the arc. In this article, I review recent modelling of this cometary appearance as a bow shock with an accompanying tail of material ram pressure stripped from the head of the bow shock, place Mira in an evolutionary context, predict its future with reference to the similar star R Hya and planetary nebula Sh 2-188, and speculate some avenues of research both on Mira itself and on other 'Mira-like' stars with bow shocks and tails. I also discuss the implications of this discovery for our own star, the Sun.

  3. Miras and Janet Mattei

    NASA Astrophysics Data System (ADS)

    Willson, L. A.

    2005-08-01

    Janet Mattei appears among the authors on over 70 papers concerning Mira variables or related classes of red variables. She contributed to the planning or execution of some of the research in this area, but more often appeared as representative for the thousands of AAVSO observers world wide. Janet also helped to start several observational programs concerning particular types of variables, and was involved with the planning and/or data analysis on space missions that observed these stars. In this review I put her contributions, and the AAVSO's contributions while she was Director, into a general context of work in this field.

  4. Mira Soars Through the Sky

    NASA Technical Reports Server (NTRS)

    2007-01-01

    [figure removed for brevity, see original site] [figure removed for brevity, see original site] Figure 1Figure 2

    New ultraviolet images from NASA's Galaxy Evolution Explorer shows a speeding star that is leaving an enormous trail of 'seeds' for new solar systems. The star, named Mira (pronounced my-rah) after the latin word for 'wonderful,' is shedding material that will be recycled into new stars, planets and possibly even life as it hurls through our galaxy.

    In figure 1, the upper panel shows Mira's full, comet-like tail as seen only in shorter, or 'far' ultraviolet wavelengths, while the lower panel is a combined view showing both far and longer, or 'near' ultraviolet wavelengths. The close-up picture at bottom gives a better look at Mira itself, which appears as a pinkish dot, and is moving from left to right in this view. Shed material appears in light blue. The dots in the picture are stars and distant galaxies. The large blue dot on the left side of the upper panel, and the large yellow dot in the lower panel, are both stars that are closer to us than Mira.

    The Galaxy Evolution Explorer discovered the strange tail during part of its routine survey of the entire sky at ultraviolet wavelengths. When astronomers first saw the picture, they were shocked because Mira has been studied for over 400 years yet nothing like this has ever been documented before.

    Mira's comet-like tail stretches a startling 13 light-years across the sky. For comparison, the nearest star to our sun, Proxima Centauri, is only about 4 light-years away. Mira's tail also tells a tale of its history -- the material making it up has been slowly blown off over time, with the oldest material at the end of the tail being released about 30,000 years ago (figure 2).

    Mira is a highly evolved, 'red giant' star near the end of its life. Technically, it is called an asymptotic giant branch star. It is red in color and bloated; for example, if a red giant were to replace

  5. Mira Soars Through the Sky

    NASA Technical Reports Server (NTRS)

    2007-01-01

    [figure removed for brevity, see original site] [figure removed for brevity, see original site] Figure 1Figure 2

    New ultraviolet images from NASA's Galaxy Evolution Explorer shows a speeding star that is leaving an enormous trail of 'seeds' for new solar systems. The star, named Mira (pronounced my-rah) after the latin word for 'wonderful,' is shedding material that will be recycled into new stars, planets and possibly even life as it hurls through our galaxy.

    In figure 1, the upper panel shows Mira's full, comet-like tail as seen only in shorter, or 'far' ultraviolet wavelengths, while the lower panel is a combined view showing both far and longer, or 'near' ultraviolet wavelengths. The close-up picture at bottom gives a better look at Mira itself, which appears as a pinkish dot, and is moving from left to right in this view. Shed material appears in light blue. The dots in the picture are stars and distant galaxies. The large blue dot on the left side of the upper panel, and the large yellow dot in the lower panel, are both stars that are closer to us than Mira.

    The Galaxy Evolution Explorer discovered the strange tail during part of its routine survey of the entire sky at ultraviolet wavelengths. When astronomers first saw the picture, they were shocked because Mira has been studied for over 400 years yet nothing like this has ever been documented before.

    Mira's comet-like tail stretches a startling 13 light-years across the sky. For comparison, the nearest star to our sun, Proxima Centauri, is only about 4 light-years away. Mira's tail also tells a tale of its history -- the material making it up has been slowly blown off over time, with the oldest material at the end of the tail being released about 30,000 years ago (figure 2).

    Mira is a highly evolved, 'red giant' star near the end of its life. Technically, it is called an asymptotic giant branch star. It is red in color and bloated; for example, if a red giant were to replace

  6. Excellent durability of Starr-Edwards ball valves implanted in the aortic and mitral positions for 27 years: report of a rare surgical case.

    PubMed

    Tochii, Masato; Takagi, Yasushi; Kaneko, Kan; Ishida, Michiko; Akita, Kiyotoshi; Higuchi, Yoshiro; Ando, Motomi

    2013-01-01

    A 59-year-old male who had undergone aortic and mitral valve replacement with Starr-Edwards ball valves 27 years ago was admitted to our hospital for hemolytic anemia and heart failure. Echocardiography revealed prosthetic valve failure with a high-pressure gradient and small effective orifice area. The Starr-Edwards ball valves were successfully replaced with bileaflet mechanical valves. The explanted valves revealed no structural abnormalities.

  7. Mira's Tail There All Along

    NASA Technical Reports Server (NTRS)

    2007-01-01

    NASA's Galaxy Evolution Explorer discovered an exceptionally long comet-like tail of material trailing behind Mira -- a star that has been studied thoroughly for about 400 years. So, why had this tail gone unnoticed for so long? The answer is that nobody had scanned the extended region around Mira in ultraviolet light until now.

    As this composite demonstrates, the tail is only visible in ultraviolet light (top), and does not show up in visible light (bottom). Incidentally, Mira is much brighter in visible than ultraviolet light due to its low surface temperature of about 3,000 kelvin (about 5,000 degrees Fahrenheit).

    The Galaxy Evolution Explorer, one of NASA's Small Explorer class missions, is the first all-sky survey in ultraviolet light. It found Mira's tail by chance during a routine scan. Since the mission's launch more than four years ago, it has surveyed millions of galaxies and stars. Such vast collections of data often bring welcome surprises, such as Mira's unusual tail.

    The visible-light image is from the United Kingdom Schmidt Telescope in Australia, via the Digitized Sky Survey, a program affiliated with the Space Telescope Science Institute, Baltimore, Md.

  8. Mira: Argonne's 10-petaflops supercomputer

    SciTech Connect

    Papka, Michael; Coghlan, Susan; Isaacs, Eric; Peters, Mark; Messina, Paul

    2013-07-03

    Mira, Argonne's petascale IBM Blue Gene/Q system, ushers in a new era of scientific supercomputing at the Argonne Leadership Computing Facility. An engineering marvel, the 10-petaflops supercomputer is capable of carrying out 10 quadrillion calculations per second. As a machine for open science, any researcher with a question that requires large-scale computing resources can submit a proposal for time on Mira, typically in allocations of millions of core-hours, to run programs for their experiments. This adds up to billions of hours of computing time per year.

  9. Mira: Argonne's 10-petaflops supercomputer

    ScienceCinema

    Papka, Michael; Coghlan, Susan; Isaacs, Eric; Peters, Mark; Messina, Paul

    2016-07-12

    Mira, Argonne's petascale IBM Blue Gene/Q system, ushers in a new era of scientific supercomputing at the Argonne Leadership Computing Facility. An engineering marvel, the 10-petaflops supercomputer is capable of carrying out 10 quadrillion calculations per second. As a machine for open science, any researcher with a question that requires large-scale computing resources can submit a proposal for time on Mira, typically in allocations of millions of core-hours, to run programs for their experiments. This adds up to billions of hours of computing time per year.

  10. Silicate condensation in Mira variables

    NASA Astrophysics Data System (ADS)

    Gail, Hans-Peter; Scholz, Michael; Pucci, Annemarie

    2016-06-01

    Context. The formation of dust in winds of cool and highly evolved stars and the rate of injection of dust into the interstellar medium is not yet completely understood, despite the importance of the process for the evolution of stars and galaxies. This holds in particular for oxygen-rich stars, where it is still not known which process is responsible for the formation of the necessary seed particles of their silicate dust. Aims: We study whether the condensation of silicate dust in Mira envelopes could be caused by cluster formation by the abundant SiO molecules. Methods: We solve the dust nucleation and growth equations in the co-moving frame of a fixed mass element for a simplified model of the pulsational motions of matter in the outer layers of a Mira variable, which is guided by a numerical model for Mira pulsations. It is assumed that seed particles form through the clustering of SiO. The calculation of the nucleation rate is based on published experimental data. The quantity of dust formed is calculated via a moment method and the calculation of radiation pressure on dusty gas is based on a dirty silicate model. Results: Dust nucleation occurs in the model at the upper culmination of the trajectory of a gas parcel where it stays for a considerable time at low temperatures. Subsequent dust growth occurs during the descending part of the motion and continues after the next shock reversed motion. It is found that sufficient dust forms that radiation pressure exceeds the gravitational pull of the stars such that the mass element is finally driven out of the star. Conclusions: Nucleation of dust particles by clustering of the abundant SiO molecules could be the mechanism that triggers silicate dust formation in Miras.

  11. Mechanical heart valve cavitation in patients with bileaflet valves.

    PubMed

    Johansen, Peter; Andersen, Tina S; Hasenkam, J Michael; Nygaard, Hans; Paulsen, Peter K

    2014-01-01

    Today, the quality of mechanical heart valves is quite high, and implantation has become a routine clinical procedure with a low operative mortality (< 5%). However, patients still face the risks of blood cell damage, thromboembolic events, and material failure of the prosthetic device. One mechanism found to be a possible contributor to these adverse effects is cavitation. In vitro, cavitation has been directly demonstrated by visualization and indirectly in vivo by registering of high frequency pressure fluctuations (HFPF). Tilting disc valves are thought of having higher cavitation potential than bileaflet valves due to higher closing velocities. However, the thromboembolic potential seems to be the same. Further studies are therefore needed to investigate the cavitation potential of bileaflet valves in vivo. The post processing of HFPF have shown difficulties when applied on bileaflet vavles due to asynchronous closure of the two leaflets. The aim of this study was therefore to isolate the pressure signature from each leaflet closure and perform cavitation analyses on each component. Six patients were included in the study (St. Jude Medical (n=3) and CarboMedics (n=3); all aortic bileaflet mechanical heart valves). HFPFs were recorded intraoperatively through a hydrophone at the aortic root. The pressure signature relating to the first and second leaflet closure was isolated and cavitation parameters were calculated (RMS after 50 kHz highpass filtering and signal energy). Data were averaged over 30 heart cycles. For all patients both the RMS value and signal energy of the second leaflet closure were higher than for the first leaflet closure. This indicates that the second leaflet closure is most prone to cause cavitation. Therefore, quantifying cavitation based on the HFPF related to the second leaflet closure may suggest that the cavitation potential for bileaflet valves in vivo may be higher than previous studies have suggested. PMID:25571278

  12. Motion Imagery and Robotics Application Project (MIRA)

    NASA Technical Reports Server (NTRS)

    Grubbs, Rodney P.

    2010-01-01

    This viewgraph presentation describes the Motion Imagery and Robotics Application (MIRA) Project. A detailed description of the MIRA camera service software architecture, encoder features, and on-board communications are presented. A description of a candidate camera under development is also shown.

  13. Motion Imagery and Robotics Application (MIRA)

    NASA Technical Reports Server (NTRS)

    Martinez, Lindolfo; Rich, Thomas

    2011-01-01

    Objectives include: I. Prototype a camera service leveraging the CCSDS Integrated protocol stack (MIRA/SM&C/AMS/DTN): a) CCSDS MIRA Service (New). b) Spacecraft Monitor and Control (SM&C). c) Asynchronous Messaging Service (AMS). d) Delay/Disruption Tolerant Networking (DTN). II. Additional MIRA Objectives: a) Demo of Camera Control through ISS using CCSDS protocol stack (Berlin, May 2011). b) Verify that the CCSDS standards stack can provide end-to-end space camera services across ground and space environments. c) Test interoperability of various CCSDS protocol standards. d) Identify overlaps in the design and implementations of the CCSDS protocol standards. e) Identify software incompatibilities in the CCSDS stack interfaces. f) Provide redlines to the SM&C, AMS, and DTN working groups. d) Enable the CCSDS MIRA service for potential use in ISS Kibo camera commanding. e) Assist in long-term evolution of this entire group of CCSDS standards to TRL 6 or greater.

  14. Introducing Mira, Argonne's Next-Generation Supercomputer

    SciTech Connect

    2013-03-19

    Mira, the new petascale IBM Blue Gene/Q system installed at the ALCF, will usher in a new era of scientific supercomputing. An engineering marvel, the 10-petaflops machine is capable of carrying out 10 quadrillion calculations per second.

  15. Mira Ceti and the Star of Bethlehem

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    We consider the probability that the Gospel of Matthew could report the earliest observation of Mira Ceti. Some biblical remarks have to be considered in order to distinguish a scientific text in the modern acceptation and the content of Gospels regarding some astronomical arguments. Mira fulfills the basic requirements to be the Star of Bethlehem as described in the Gospel according to Matthew (Mt 2:1-12). In fact it was visible at least two times with a time interval (not specified in Mt text) in which it disappeared. Moreover Mira was close to the position were the triple conjunction of Jupiter and Saturn occurred in the years 7-6 b. C. and it could be observed during that period by ancient astronomers. The discovery of Mira in 1596 and its second observation 12.5 years later, made by David Fabricius, occurred when Jupiter approached it. Because of those reasons we study the maxima of Mira in order to evaluate both the frequency of one and of two consecutive bright apparitions eventually as observed by the Magi. We did an evaluation of the correlation between two following maxima in order to verify the probability of occurrence of two consecutive bright maxima, because that condition would have been indeed the most favorable for the candidature of Mira as the Bethlehem Star. Analyzing the maxima of Mira we found a probability of seeing it brighter than α Ceti once every 21 years. In this case, as in February 1997, Mira can be detected at the first sight as a new component near the most significant asterism in its zone, composed by α, γ and δ Ceti. This condition could have happened in the case of the Bethlehem Star. We found also a correlation between the magnitude of two consecutive maxima: if a bright maximum occurs it is more probable that the following is a faint one.

  16. Mira Ceti and the Star of Bethlehem

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2014-05-01

    We consider the probability that the Gospel of Matthew could report the earliest observation of Mira Ceti. Some biblical remarks have to be considered in order to distinguish a scientific text in the modern acceptation and the content of Gospels regarding some astronomical arguments. Mira fulfills the basic requirements to be the Star of Bethlehem as described in the Gospel according to Matthew (Mt 2:1-12). In fact it was visible at least two times with a time interval (not specified in Mt text) in which it disappeared. Moreover Mira was close to the position were the triple conjunction of Jupiter and Saturn occurred in the years 7-6 b. C. and it could be observed during that period by ancient astronomers. The discovery of Mira in 1596 and its second observation 12.5 years later, made by David Fabricius, occurred when Jupiter approached it. Because of those reasons we study the maxima of Mira in order to evaluate both the frequency of one and of two consecutive bright apparitions eventually as observed by the Magi. We did an evaluation of the correlation between two following maxima in order to verify the probability of occurrence of two consecutive bright maxima, because that condition would have been indeed the most favorable for the candidature of Mira as the Bethlehem Star. Analyzing the maxima of Mira we found a probability of seeing it brighter than alpha Ceti once every 21 years. In this case, as in February 1997, Mira can be detected at the first sight as a new component near the most significant asterism in its zone, composed by alpha, gamma and delta Ceti. This condition could have happened in the case of the Bethlehem Star. We found also a correlation between the magnitude of two consecutive maxima: if a bright maximum occurs it is more probable that the following is a faint one.

  17. The Bright Symbiotic Mira EF Aquilae

    NASA Astrophysics Data System (ADS)

    Margon, Bruce; Prochaska, J. Xavier; Tejos, Nicolas; Monroe, TalaWanda

    2016-02-01

    An incidental spectrum of the poorly studied long-period variable EF Aquilae shows [O III] emission indicative of a symbiotic star. Strong GALEX detections in the UV reinforce this classification, providing overt evidence for the presence of the hot subluminous companion. Recent compilations of the photometric behavior strongly suggest that the cool component is a Mira variable. Thus EF Aql appears to be a member of the rare symbiotic Mira subgroup.

  18. History of the Discovery of Mira Stars

    NASA Astrophysics Data System (ADS)

    Hoffleit, Dorrit

    This year we celebrate the 400th anniversary of Fabricius' discovery of Mira, "The Wonderful," in 1596. But was he the first? Within the first century following Fabricius, four Mira-type variables were discovered, and in all cases it has been found that the stars were suspected of being novae long before their "official" discovery in the Western World. Three of the four had been recorded as novae in early Chinese or Korean records. By 1896, 251 Mira-type variabes had been discovered, most of them after the beginning of photographic experimentation. Now in the year of the fourth centennial, over 6000 Miras are known. Because of their ease of discovery relative to stars of small amplitude, no new Mira stars reaching naked-eye visibility have been discovered since 1899. The history of the discovery of Mira-type variables illustrates that (1) some new discoveries are re-discoveries of objects previously assumed to be novae; and (2) apparently logical deductions that early observations of a guest star correspond to a later discovered Mire-type may nevertheless be wrong.

  19. Measurements of flow past a bileaflet mechanical heart valve

    NASA Astrophysics Data System (ADS)

    Haya, Laura; Tavoularis, Stavros

    2013-11-01

    A bileaflet mechanical heart valve has been inserted in an axisymmetric model of the aorta within a mock circulation apparatus with physiological pressure and flow variations. The velocity field behind the valve has been measured with laser Doppler velocimetry and particle image velocimetry. The results closely match those reported by similar studies. A triple jet emanated from the valve's orifices and regions of reverse flow formed in the sinus region. Velocity fluctuations were greatest in the shear layers of the jets. The average r.m.s. streamwise velocity fluctuation over the turbulent period was 0.22 m/s; its maximum value was 0.53 m/s and occurred at the onset of deceleration. Measurements with the valve inserted in an anatomical model of the aorta are planned for the near future. The present and future measurements will be compared to determine the effects of the aorta anatomy on the characteristics of flow through bileaflet valves. In particular, measurements of the viscous and turbulent shear stresses will be analyzed to identify possible locations of blood element damage, and regions of recirculation and stagnation will be identified as locations favourable to thrombus growth. The effects of flows in branching arteries and valve orientation will also be investigated. Supported by NSERC.

  20. Effects of bileaflet mechanical heart valve orientation on coronary flow

    NASA Astrophysics Data System (ADS)

    Haya, Laura; Tavoularis, Stavros

    2015-11-01

    The aortic sinus is approximately tri-radially symmetric, but bileaflet mechanical heart valves (BMHVs), which are commonly used to replace diseased aortic valves, are bilaterally symmetric. This mismatch in symmetry suggests that the orientation in which a BMHV is implanted within the aortic sinus affects the flow characteristics downstream of it. This study examines the effect of BMHV orientation on the flow in the coronary arteries, which originate in the aortic sinus and supply the heart tissue with blood. Planar particle image velocimetry measurements were made past a BMHV mounted at the inlet of an anatomical aorta model under physiological flow conditions. The complex interactions between the valve jets, the sinus vortex and the flow in the right coronary artery were elucidated for three valve orientations. The coronary flow rate was directly affected by the size, orientation, and time evolution of the vortex in the sinus, all of which were sensitive to the valve's orientation. The total flow through the artery was highest when the valve was oriented with its axis of symmetry intersecting the artery's opening. The findings of this research may assist surgeons in choosing the best orientation for BMHV implantation. The bileaflet valve was donated by St. Jude Medical. Financial support was provided by the Natural Sciences and Engineering Research Council of Canada.

  1. Computational Simulation of Blood Flow through Bileaflet Heart Valve Prostheses

    NASA Astrophysics Data System (ADS)

    Healy, Timothy; Sotiropoulos, Fotis; Yoganathan, Ajit

    2001-11-01

    Non-physiologic flow patterns and levels of turbulence caused by contemporary bileaflet mechanical heart valve (MHV) designs are believed to be partially responsible for thromboembolic complications caused by these valves. Presently, computer-based flow assessment is not employed as a design tool. Rather, CFD is used to understand flow dynamics under highly-specialized circumstances after a design has been selected and tested experimentally. The absence of CFD from the design-screening process is most likely due to undeveloped tools specific to the heart valve problem. CFD tools for assessing MHV flow performance should be efficient at simulating the fluid-structure interaction and the resulting leaflet motion. As the first stage in the development of MHV simulation tools, a high-accuracy Chimera solver was developed and tested for laminar flow through two bileaflet MHV designs. Steady and time-dependent simulations were performed providing the highest resolution simulations of three-dimensional MHV flow fields to date. Flow structures and time-dependent flow phenomena were investigated and interpreted in the context of the clinical performance of each design studied.

  2. Edward Hopper: The Watercolors.

    ERIC Educational Resources Information Center

    Johnson, Mark M.

    2000-01-01

    Provides information on Edward Hopper, focusing on his use of watercolors. Explores five of his watercolor paintings: (1) "The Mansard Roof"; (2) "House on Pamet River"; (3) "Light at Two Lights"; (4) "Saltillo Mansion"; and (5) "Roofs of Washington Square." Addresses the exhibition "Edward Hopper: The Watercolors." (CMK)

  3. Atmospheric structure and mass loss in Miras

    NASA Astrophysics Data System (ADS)

    Hinkle, Kenneth H.; Lebzelter, Thomas; Straniero, Oscar

    2016-07-01

    The cool molecular region of late-type stellar atmospheres, the ‘MOLsphere’ located between the photosphere and expanding circumstellar shell, is explored by using time series of near-IR spectra of one large amplitude AGB (Mira) variable. The ∼⃒1400 K MOLsphere of the Mira R Cas is shown to undergo large amplitude velocity changes that are aperiodic with time scales many times longer than the photospheric pulsation. The mass of the MOLsphere is ∼⃒3×10‑5 M⊙. Initial analysis suggests that MOLsphere is thin compared to the stellar radius.

  4. A case of the Starr-Edwards ball valve (Model 6120) in the mitral position for 45 years.

    PubMed

    Azuma, Shuhei; Morita, Masafumi; Yoshii, Yasuhiro; Mieno, Shigetoshi

    2015-02-01

    A 59-year-old male who had undergone mitral valve replacement with the Starr-Edwards ball valve Model 6120 (S-E ball valve) 45 years ago was admitted to our hospital for hemolytic anemia and heart failure. Echocardiography revealed that there was no valve dysfunction but paravalvular leakage between the annulus of P2 and the sewing ring of the Starr-Edwards ball valve. He underwent mitral valve replacement. The S-E ball valve was successfully replaced with bileaflet mechanical valve. The explanted S-E ball valve was free from signs of structural valve degeneration. This case shows one of the longest durability of the S-E ball valve in mitral position in the world.

  5. Ascending aortic aneurysm in a patient with an aortic Starr-Edwards ball valve prosthesis implanted 39 years previously.

    PubMed

    Nishigawa, Kosaku; Totsugawa, Toshinori; Yoshitaka, Hidenori; Tsushima, Yoshimasa; Kuinose, Masahiko; Chikazawa, Genta

    2010-03-01

    A 53-year-old man who had undergone aortic valve replacement with a Starr-Edwards ball valve prosthesis 39 years previously was admitted to our hospital under the diagnosis of ascending aortic aneurysm. Operative findings revealed that the ball valve was functioning normally. The markedly dilated ascending aorta was replaced with a 30-mm prosthetic vascular graft, and the ball valve was replaced with a19-mm bileaflet valve prosthesis. The patient's postoperative course was uneventful, and he was discharged from our hospital 19 days after surgery. Dilatation of the ascending aorta in this case might have been caused by the poststenotic dilatation mechanism, which seems to be one of the long-term complications of Starr-Edwards ball valve implantation.

  6. The radio continuum spectrum of Mira A and Mira B up to submillimeter wavelengths

    NASA Astrophysics Data System (ADS)

    Planesas, P.; Alcolea, J.; Bachiller, R.

    2016-02-01

    Aims: We present new measurements of the flux densities at submillimeter wavelengths based on ALMA band 7 (338 GHz, λ0.89 mm) and band 9 (679 GHz, λ0.44 mm) observations to better constrain the origin of the continuum emission of the Mira AB binary system and to check its orbit. Methods: We have measured the Mira A and Mira B continuum in ALMA band 7, with a resolution of ~0.̋31, and for the first time in ALMA band 9, with a resolution of ~0.̋18. We have resolved the binary system at both bands, and derived the continuum spectral index of the stars and their relative position. We also analyzed ALMA Science Verification data obtained in bands 6 and 3. Measurements at centimeter wavelengths obtained by other authors have been included in our study of the spectral energy distribution of the Mira components. Results: The Mira A continuum emission has a spectral index of 1.98 ± 0.04 extending from submillimeter down to centimeter wavelengths. The spectral index of the Mira B continuum emission is 1.93 ± 0.06 at wavelengths ranging from submillimeter to ~3.1 mm, and a shallower spectral index of 1.22 ± 0.09 at longer wavelengths. The high precision relative positions of the A and B components are shown to significantly depart from the current (preliminary) orbit by ~14 mas. Conclusions: The Mira A continuum emission up to submillimeter wavelengths is consistent with that of a radio photosphere surrounding the evolved star for which models predict a spectral index close to 2. The Mira B continuum emission cannot be described with a single ionized component. An extremely compact and dense region around the star can produce the nearly thermal continuum measured in the range λ0.4-3.1 mm, and an inhomogeneous, less dense, and slightly larger ionized envelope could be responsible for the emission at longer wavelengths. Our results illustrate the potential of ALMA for high precision astrometry of binary systems. We have found a significant discrepancy between the ALMA

  7. Large stellar interferometer MIRA-ST

    NASA Astrophysics Data System (ADS)

    Yoshizawa, Masanori; Sato, Koichi; Nishikawa, Jun; Ohishi, Naoko; Kotani, Takayuki

    2003-02-01

    We propose a millisecond of arc optical/infrared array for stellar territory, MIRA-ST, with nine 4m-aperture off-axis telescopes, whose maximum baseline length is about 600 m. MIRA-ST will have the photon collecting area equivalent to that of a single-dish telescope of 12 m diameter, and the imaging capability better than 1 millisecond of arc resolution at 2.2 micrometers with a high dynamic range of reconstructed images. Combining the light beams from each pupil telescope efficiently is one of the most difficult tasks. We compare the relative merits among a so-called pair-wise beam combining, an all-on-one beam combining, and a tree-structured beam combining. As for transferring the beams from individual telescopes to a beam combining facility with the loss of photons as small as possible, an optical fiber system is a most interesting substitute for the current mirror-and-vacuum-pipe combination. Specifically, the nature of spatial filtering of optical fibers has been under study in the light of deepening the limiting magnitude attainable without introducing an adaptive optics to each telescope. With MIRA-ST we will be able to zoom in the stellar territory to unveil the detailed structures and lifecycles of stars of various kinds, and to examine the universality and/or diversity along the coarse of their evolutionary paths. The specific targets of most interesting for us are, among others, T Tauri stars, AGB and post-AGB stars, Cepheids, brown dwarfs, white dwarfs, stellar atmosphere/envelope of low temperature stars, accretion disks, and fundamental structures of main sequence stars.

  8. A novel computational model for the hemodynamics of bileaflet mechanical valves in the opening phase.

    PubMed

    Jahandardoost, Mehdi; Fradet, Guy; Mohammadi, Hadi

    2015-03-01

    A powerful alternative means to study the hemodynamics of bileaflet mechanical heart valves is the computational fluid dynamics method. It is well recognized that computational fluid dynamics allows reliable physiological blood flow simulation and measurements of flow parameters. To date, in almost all of the modeling studies on the hemodynamics of bileaflet mechanical heart valves, a velocity (mass flow)-based boundary condition and an axisymmetric geometry for the aortic root have been assigned, which, to some extent, are erroneous. Also, there have been contradictory reports of the profile of velocity in downstream of leaflets, that is, in some studies, it is suggested that the maximum blood velocity occurs in the lateral orifice, and in some other studies, it is postulated that the maximum velocities in the main and lateral orifices are identical. The reported values for the peak velocities range from 1 to 3 m/s, which highly depend on the model assumptions. The objective of this study is to demonstrate the importance of the exact anatomical model of the aortic root and the realistic boundary conditions in the hemodynamics of the bileaflet mechanical heart valves. The model considered in this study is based on the St Jude Medical valve in a novel modeling platform. Through a more realistic geometrical model for the aortic root and the St Jude Medical valve, we have developed a new set of boundary conditions in order to be used for the assessment of the hemodynamics of aortic bileaflet mechanical heart valves. The results of this study are significant for the design improvement of conventional bileaflet mechanical heart valves and for the design of the next generation of prosthetic valves.

  9. A novel computational model for the hemodynamics of bileaflet mechanical valves in the opening phase.

    PubMed

    Jahandardoost, Mehdi; Fradet, Guy; Mohammadi, Hadi

    2015-03-01

    A powerful alternative means to study the hemodynamics of bileaflet mechanical heart valves is the computational fluid dynamics method. It is well recognized that computational fluid dynamics allows reliable physiological blood flow simulation and measurements of flow parameters. To date, in almost all of the modeling studies on the hemodynamics of bileaflet mechanical heart valves, a velocity (mass flow)-based boundary condition and an axisymmetric geometry for the aortic root have been assigned, which, to some extent, are erroneous. Also, there have been contradictory reports of the profile of velocity in downstream of leaflets, that is, in some studies, it is suggested that the maximum blood velocity occurs in the lateral orifice, and in some other studies, it is postulated that the maximum velocities in the main and lateral orifices are identical. The reported values for the peak velocities range from 1 to 3 m/s, which highly depend on the model assumptions. The objective of this study is to demonstrate the importance of the exact anatomical model of the aortic root and the realistic boundary conditions in the hemodynamics of the bileaflet mechanical heart valves. The model considered in this study is based on the St Jude Medical valve in a novel modeling platform. Through a more realistic geometrical model for the aortic root and the St Jude Medical valve, we have developed a new set of boundary conditions in order to be used for the assessment of the hemodynamics of aortic bileaflet mechanical heart valves. The results of this study are significant for the design improvement of conventional bileaflet mechanical heart valves and for the design of the next generation of prosthetic valves. PMID:25833999

  10. Edward Teller's Scientific Life

    SciTech Connect

    Libby, S B; Weiss, M S

    2004-04-15

    Edward Teller was one of the great physicists of the twentieth century. His career began just after the key ideas of the quantum revolution of the 1920's were completed, opening vast areas of physics and chemistry to detailed understanding. Thus, his early work in theoretical physics focused on applying the new quantum theory to the understanding of diverse phenomena. These topics included chemical physics, diamagnetism, and nuclear physics. Later, he made key contributions to statistical mechanics, surface physics, solid state, and plasma physics. In many cases, the ideas in these papers are still rich with important ramifications.

  11. Discovering Mira Ceti: Celestial Change and Cosmic Continuity

    NASA Astrophysics Data System (ADS)

    Hatch, Robert Alan

    In the short narrative that follows I introduce two new heroes. Although we begin with Fabricius's first sighting in 1596, the new pivot point in the drama is the collaboration between Hevelius and Boulliau that began around 1660. As it happens, Learned Europe paid little attention to Mira in the generation after the first scattered sightings of 1596, indeed, nearly 70 years passed before the New Star was given a working identity. Like Columbus discovering America, Fabricius and Holwarda saw different things - for convenience, I call them Fabricius's Star and Holwarda's Star. Hevelius's Historiola (Danzig, 1662) and Boulliau's Ad astronomos (Paris, 1667) presented a different vision. It made Mira famous. As I shall argue, if Hevelius gave Mira a history, Boulliau gave Mira a future.5 In the end, the New Star not only challenged the ancient cosmos, it became an enduring icon for the New Science, a returning reminder of celestial continuity and cosmic order.

  12. Edward Teller Biographical Memoir

    SciTech Connect

    Libby, S B; Sessler, A M

    2009-07-27

    Edward Teller died on September 9, 2003 in Stanford, California at the age of 95. He was both one of the great theoretical physicists of the twentieth century and a leading figure in the development of nuclear weapons and broader defense advocacy. Teller's work in physics, spanning many decades of the twentieth century, includes some of the most fundamental insights in the quantum behaviors of molecules and their spectra, nuclei, surfaces, solid state and spin systems, and plasmas. In the defense arena, Teller is best known for his key insight that made thermonuclear weapons possible. Teller was both a great scientific collaborator and physics teacher at all levels, known for his openness, generosity, personal warmth, and powerful physical intuition. Many of his graduate students went on to illustrious careers.

  13. 02-NIF Dedication: Edward Moses

    ScienceCinema

    Edward Moses

    2016-07-12

    The National Ignition Facility, the world's largest laser system, was dedicated at a ceremony on May 29, 2009 at Lawrence Livermore National Laboratory. These are the remarks by NIF Director Edward Moses.

  14. 02-NIF Dedication: Edward Moses

    SciTech Connect

    Edward Moses

    2009-07-02

    The National Ignition Facility, the world's largest laser system, was dedicated at a ceremony on May 29, 2009 at Lawrence Livermore National Laboratory. These are the remarks by NIF Director Edward Moses.

  15. Edward A. Bouchet

    NASA Astrophysics Data System (ADS)

    Mickens, R. E.

    2002-04-01

    Edward A. Bouchet was the first African American to receive the doctorate in any field of knowledge in the United States and that area was physics. He was granted the degree in 1876 from Yale University making him at that time one of the few persons to hold the physics doctorate from an American university. His prior education included the Hopkins Grammar School and Yale College (BA in 1874). After Yale, Bouchet taught mathematics, physics, and chemistry for over twenty-five years at the Institute for Colored Youth in Philadelphia. During the following two decades, he was employed in positions ranging from high school principal to employment by the federal government. Bouchet played a significant role in the education of African Americans through his teaching and mentoring activities. He was one among a small group of African Americans who achieved advanced training and education within decades of the American civil war. These individuals provided direction, leadership, and role models for what eventually became the civil/human rights movements. The year 2001 marks the 125th celebration of his receiving the doctorate. We present details of his life and career with an emphasis on the influence of the political and social forces exerted on him by society.

  16. Pulsational Modes of Mira Variables Examined through IR Interferometry

    NASA Astrophysics Data System (ADS)

    Creech-Eakman, M. J.; Thompson, R. R.; van Belle, G. T.

    1999-12-01

    We have undertaken a program with the Palomar Testbed Interferometer (PTI) to measure the angular size variations, with respect to pulsational phase, of a group of about 20 mainly O-rich Mira variables. While previous groups have attempted to measure angular size with phase (van Belle et al. 1996, 1997; Tej et al. 1999) these are the first dedicated, spatially-resolved K band observations designed to detect size variations in a large sample of Miras at regular intervals over their pulsation periods. Our first goal has been the unambiguous detection of the mira pulsational cycle with phase, already shown in previous work to be as much as 35% of the radial size over the course of a pulsational period (van Belle et al. 1996; Burns et al. 1997; Tuthill et al. 1995; Perrin et al. 1999 ). We will ultimately use these data, along with the best estimates of stellar distance and effective temperatures for these sources, to determine the mode of pulsation. There has long been a debate as to whether Mira variables pulsate in their fundamental or first-overtone mode (Barthes 1999; Feast 1998; Wood and Sebo 1996). Determination of the pulsation behavior of Mira variables may eventually render them suitable as standard candles for distance determination.

  17. Edward (Ed) T. Schneider

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Research Pilot Edward T. Schneider is shown sitting in the cockpit of a McDonnell Douglas F/A-18 Hornet that was used in the High Angle-of-Attack Research Vehicle (HARV) program at the National Aeronautics and Space Administration's Ames - Dryden Flight Research Facility. When the aircraft arrived at the Dryden Facility in 1987, from the US Naval Air Test Center, Patuxent River, Maryland, it consisted of parts in crates. The aircraft crew made an airplane from those parts, and in doing so they took a 'sow's ear' and created a 'silk purse', thus the name on the side of the aircraft. Ed's helmet is from his time in the Navy. The design was taken from the Flag that is flown on the bow of a Navy ship, referred to as the Jack, and is navy blue with the 50 States being represented by the white stars. Ed arrived at the NASA Ames-Dryden Flight Research Facility (later renamed the Dryden Flight Research Center) on July 5, 1982, as a Navy Liaison Officer, becoming a NASA research pilot one year later. Ed was the project pilot for the F-18 High Angle-of-Attack program and later served as a project pilot for the F-15 aeronautical research aircraft, the NASA B-52 launch aircraft, and the SR-71 'Blackbird' aircraft. He served on active duty with the U.S. Navy from 1968 to 1983. Following squadron service he graduated from the U.S. Naval Test Pilot School, Patuxent River, Maryland, in 1973, and then served as an engineering test pilot, and test pilot school instructor at the Naval Air Test Center. Ed has been an active member of the Society of Experimental Test Pilots since 1974. He was made a Fellow of the Society in 1993 and served as its President in 1993/94. In 1996 he was awarded the NASA Exceptional Service Medal and the American Institute of Aeronautics and Astronautics' Chanute Flight Award. He retired as a NASA research pilot in September 2000.

  18. A MODEL OF MIRA'S COMETARY HEAD/TAIL ENTERING THE LOCAL BUBBLE

    SciTech Connect

    Esquivel, A.; Raga, A. C.; RodrIguez-Gonzalez, A.; Lopez-Camara, D.; Velazquez, P. F.; Canto, J.; De Colle, F. E-mail: raga@nucleares.unam.m E-mail: pablo@nucleares.unam.m

    2010-12-20

    We model the cometary structure around Mira as the interaction of an asymptotic giant branch stellar wind from Mira A with a streaming environment. Our simulations introduce the following new element: we assume that after 200 kyr of evolution in a dense environment, Mira entered the Local Bubble (low-density coronal gas). As Mira enters the bubble, the head of the comet expands quite rapidly, while the tail remains well collimated for a >100 kyr timescale. The result is a broad-head/narrow-tail structure that resembles the observed morphology of Mira's comet. The simulations were carried out with our new adaptive grid code WALICXE, which is described in detail.

  19. The wonderful complexity of the Mira AB system

    NASA Astrophysics Data System (ADS)

    Ramstedt, S.; Mohamed, S.; Vlemmings, W. H. T.; Maercker, M.; Montez, R.; Baudry, A.; De Beck, E.; Lindqvist, M.; Olofsson, H.; Humphreys, E. M. L.; Jorissen, A.; Kerschbaum, F.; Mayer, A.; Wittkowski, M.; Cox, N. L. J.; Lagadec, E.; Leal-Ferreira, M. L.; Paladini, C.; Pérez-Sánchez, A.; Sacuto, S.

    2014-10-01

    We have mapped the 12CO(3-2) line emission around the Mira AB system at 0.̋5 resolution using the Atacama Large Millimeter/submillimeter Array (ALMA). The CO map shows amazing complexity. The circumstellar gas has been shaped by different dynamical actors during the evolution of the system, and several morphological components can be identified. The companion is marginally resolved in continuum emission and is currently at 0.̋487 ± 0.̋006 separation. In the main line component, centered on the stellar velocity, spiral arcs around Mira A are found. The spiral appears to be relatively flat and oriented in the orbital plane. An accretion wake behind the companion is clearly visible, and the projected arc separation is about 5''. In the blue wing of the line emission, offset from the main line, several large (~5-10'') opposing arcs are found. We tentatively suggest that this structure is created by the wind of Mira B blowing a bubble in the expanding envelope of Mira A. Appendix A is available in electronic form at http://www.aanda.org

  20. A Large X-Ray Outburst in Mira A

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita; Schlegel, Eric; Hack, Warren; Raymond, John C.; Wood, Brian E.

    2005-04-01

    We report the Chandra ACIS-S detection of a bright soft X-ray transient in the Mira AB interacting symbiotic-like binary. We have resolved the system for the first time in X-rays. Using Chandra and Hubble Space Telescope images, we determine that the unprecedented outburst is likely associated with the cool asymptotic giant branch (AGB) star, Mira A, the prototype of the Mira class of variables. X-rays have never before been detected from an AGB star, and the recent activity signals that the system is undergoing dramatic changes. The total X-ray luminosity of the system is several times higher than the luminosity estimated using previous XMM-Newton and ROSAT observations. The outburst may be caused by a giant flare in Mira A associated with a mass ejection or a jet and may have long-term consequences on the system. We dedicate this paper to the memory of Janet A. Mattei, who inspired this work and made these observations possible for many years.

  1. A D-Shaped Bileaflet Bioprosthesis which Replicates Physiological Left Ventricular Flow Patterns

    PubMed Central

    Tan, Sean Guo-Dong; Kim, Sangho; Hon, Jimmy Kim Fatt; Leo, Hwa Liang

    2016-01-01

    Prior studies have shown that in a healthy heart, there exist a large asymmetric vortex structure that aids in establishing a steady flow field in the left ventricle. However, the implantation of existing artificial heart valves at the mitral position is found to have a negative effect on this physiological flow pattern. In light of this, a novel D-shaped bileaflet porcine bioprosthesis (GD valve) has been designed based on the native geometry mitral valve, with the hypothesis that biomimicry in valve design can restore physiological left ventricle flow patterns after valve implantation. An in-vitro experiment using two dimensional particle velocimetry imaging was carried out to determine the hemodynamic performance of the new bileaflet design and then compared to that of the well-established St. Jude Epic valve which functioned as a control in the experiment. Although both valves were found to have similar Reynolds shear stress and Turbulent Kinetic Energy levels, the novel D-shape valve was found to have lower turbulence intensity and greater mean kinetic energy conservation. PMID:27258099

  2. A D-Shaped Bileaflet Bioprosthesis which Replicates Physiological Left Ventricular Flow Patterns.

    PubMed

    Tan, Sean Guo-Dong; Kim, Sangho; Hon, Jimmy Kim Fatt; Leo, Hwa Liang

    2016-01-01

    Prior studies have shown that in a healthy heart, there exist a large asymmetric vortex structure that aids in establishing a steady flow field in the left ventricle. However, the implantation of existing artificial heart valves at the mitral position is found to have a negative effect on this physiological flow pattern. In light of this, a novel D-shaped bileaflet porcine bioprosthesis (GD valve) has been designed based on the native geometry mitral valve, with the hypothesis that biomimicry in valve design can restore physiological left ventricle flow patterns after valve implantation. An in-vitro experiment using two dimensional particle velocimetry imaging was carried out to determine the hemodynamic performance of the new bileaflet design and then compared to that of the well-established St. Jude Epic valve which functioned as a control in the experiment. Although both valves were found to have similar Reynolds shear stress and Turbulent Kinetic Energy levels, the novel D-shape valve was found to have lower turbulence intensity and greater mean kinetic energy conservation.

  3. A D-Shaped Bileaflet Bioprosthesis which Replicates Physiological Left Ventricular Flow Patterns.

    PubMed

    Tan, Sean Guo-Dong; Kim, Sangho; Hon, Jimmy Kim Fatt; Leo, Hwa Liang

    2016-01-01

    Prior studies have shown that in a healthy heart, there exist a large asymmetric vortex structure that aids in establishing a steady flow field in the left ventricle. However, the implantation of existing artificial heart valves at the mitral position is found to have a negative effect on this physiological flow pattern. In light of this, a novel D-shaped bileaflet porcine bioprosthesis (GD valve) has been designed based on the native geometry mitral valve, with the hypothesis that biomimicry in valve design can restore physiological left ventricle flow patterns after valve implantation. An in-vitro experiment using two dimensional particle velocimetry imaging was carried out to determine the hemodynamic performance of the new bileaflet design and then compared to that of the well-established St. Jude Epic valve which functioned as a control in the experiment. Although both valves were found to have similar Reynolds shear stress and Turbulent Kinetic Energy levels, the novel D-shape valve was found to have lower turbulence intensity and greater mean kinetic energy conservation. PMID:27258099

  4. Foreword by Edward Michael Campbell

    NASA Astrophysics Data System (ADS)

    Campbell, Edward Michael

    2016-10-01

    The Edward Teller medal has evolved into one of the most prestigious awards that recognizes the outstanding contributions to the field of inertial confinement fusion and high energy density science. It is appropriate that this international award be named after Teller, who with extraordinary vision and scientific insight, anticipated and then played a major role in the creation of this field...

  5. Morphology and kinematics of the gas envelope of Mira Ceti

    NASA Astrophysics Data System (ADS)

    Nhung, P. T.; Hoai, D. T.; Diep, P. N.; Phuong, N. T.; Thao, N. T.; Tuan-Anh, P.; Darriulat, P.

    2016-07-01

    Observations of 12CO(3-2) emission of the circumbinary envelope of Mira Ceti, made by Atacama Large Millimetre/sub-millimetre Array, are analysed. The observed Doppler velocity distribution is made of three components: a blueshifted south-eastern arc, which can be described as a ring in slow radial expansion, ˜1.7 km s-1, making an angle of ˜50° with the plane of the sky and born some 2000 years ago; a few arcs, probably born at the same epoch as the blueshifted arc, all sharing Doppler velocities redshifted by approximately 3±2 km s-1 with respect to the main star; thirdly, a central region dominated by the circumbinary envelope, displaying two outflows in the south-western and north-eastern hemispheres. At short distances from the star, up to ˜1.5 arcsec, these hemispheres display very different morphologies: the south-western outflow covers a broad solid angle, expands radially at a rate between 5 and 10 km s-1 and is slightly redshifted; the north-eastern outflow consists of two arms, both blueshifted, bracketing a broad dark region where emission is suppressed. At distances between ˜1.5 and ˜2.5 arcsec the asymmetry between the two hemispheres is significantly smaller and detached arcs, particularly spectacular in the north-eastern hemisphere are present. Close to the stars, we observe a mass of gas surrounding Mira B, with a size of a few tens of au, and having Doppler velocities with respect to Mira B reaching ±1.5 km s-1, which we interpret as gas flowing from Mira A towards Mira B.

  6. Mass loss and OH maser emission from Mira variables

    NASA Technical Reports Server (NTRS)

    Michalitsianos, A. G.; Kafatos, M.

    1978-01-01

    The mass, radius, and luminosity of 26 Mira variables that are known OH sources of radio emission at 1612 MHz have been estimated. The time-independent solution of Salpeter's (1974) stellar-wind equation and a period-density relation are used to solve for basic stellar parameters, with the aid of the terminal expansion velocity of the OH maser cloud. Masses obtained from these calculations are consistent with other estimated values for masses of Mira variables. Good agreement is obtained when comparing the rate of mass loss as determined from Reimers's (1977) semiempirical relation with estimates of the mass-loss rate as deduced from theoretical models involving radiation pressure on grains. These calculations suggest a strong correlation between the mass-loss rate and the pulsation period. Arguments concerning the general properties of silicate grains from radiation-pressure-driven stellar-wind equations are discussed.

  7. Loops in Bandstrength-Color Diagrams for Mira Variables

    NASA Astrophysics Data System (ADS)

    Wing, R. P.

    Narrow-band photometry of Mira variables in the near-infrared (7000-11000 AA) spectral region allows the measurement of colors at relatively good continuum points as well as strong bands of TiO and VO. Several variables including o Cet, chi Cyg, R And, R Cas, R Tri, and IK Tau have been followed through two or more cycles; 27 stars were observed on 10 or more dates. In bandstrength-color diagrams, Mira variables execute large, open loops of varying character and complexity. Several of these are illustrated and discussed. Attempts to model these loops may shed light on the temperature structures of the outer layers of these stars' extended, dynamic atmospheres.

  8. Multi-color interferometric observations of Mira stars

    NASA Technical Reports Server (NTRS)

    Mennesson, B.; Creech-Eakman, M.; Thompson, B. B.; Foresto, V. Coude du; Merand, A.; Ridgway, S.; Perrin, G.

    2002-01-01

    Interferometric observations in the atmospheric windows of the near infrared (1 to 4 microns) can be efficiently used to probe the chemical composition of Miras atmosphere and provide direct measurements of extended gas layers around these stars. This is illustrated by recent Miras observations carried out with the FLUOR instrument of the IOTA interferometer (Mennesson et al. 2002, and Perrin et al. proceedings of this conference) and with the PTI test-bed (Thompson 2002, Thompson et al. 2002). These visibility measurements show evidence for continuum emission from very extended ( 2-3 stellar radii) semi-transparent gaseous atmospheric layers, and large apparent diameter changes with pulsation phase. Interestingly these observations are consistent with the extended molecular gas layers (H20, CO ...) already inferred around some of these objects from IS0 and high resolution ground-based FTS infrared spectra.

  9. Transapical off-pump Neochord implantation on bileaflet prolapse to treat severe mitral regurgitation.

    PubMed

    Colli, Andrea; Bellu, Roberto; Pittarello, Demetrio; Gerosa, Gino

    2015-10-01

    A 74-year old lady was admitted for the presence of a symptomatic severe mitral regurgitation (MR) due to bileaflet prolapse. The patient refused any surgical conventional procedure because of severe arthrosis and osteoporosis documented by previous fractures requiring knee and hip replacements, and was sent directly to us for transapical off-pump mitral valve repair with Neochord implantation (TOP-MINI procedure). The TOP-MINI procedure was performed under general anaesthesia and transoesophageal echocardiographic guidance. Four Neochordae were implanted on the posterior leaflet and two on the anterior leaflet in order to correct a residual anterior prolapse that was not seen at preoperative screening. After 11 months of follow-up, the patient presented with recurrence of symptomatic moderate MR due to rupture of one of two neochordae implanted on the anterior leaflet and new onset of atrial fibrillation. The patient underwent uneventful mitral valve replacement. PMID:26180097

  10. Mitigation of Shear-Induced Blood Damage by Mechanical Bileaflet Heart Valves

    NASA Astrophysics Data System (ADS)

    Zakharin, Boris; Arjunon, Sivakkumar; Saikrishnan, Neelakantan; Yoganathan, Ajit; Glezer, Ari

    2010-11-01

    The strong transitory shear stress generated during the time-periodic closing of bileaflet mechanical heart valves that is associated with the formation of counter-rotating vortices near the leaflet edges may be damaging to blood elements and may result in platelet activation and therefore thrombosis and thromboembolism complications. These flow transients are investigated using fluorescent PIV in a new, low-volume test setup that reproduces the pulsatile physiological conditions associated with a 25 mm St. Jude Medical valve. The flow transients are partially suppressed and the platelet activation is minimized using miniature vortex generator arrays that are embedded on the surface of the leaflets. Measurements of the ensuing flow taken phase-locked to the leaflet motion demonstrate substantial modification of the transient vertical structures and concomitant reduction of Reynolds shear stresses. Human blood experiments validated the effectiveness of miniature vortex generators in reducing thrombus formation by over 42 percent.

  11. Clarence Edwards Middle School: Success through Transformation

    ERIC Educational Resources Information Center

    Massachusetts 2020, 2012

    2012-01-01

    Just a few years ago, Boston's Clarence Edwards Middle School was on the verge of being shut down. By 2009, a renaissance at the Edwards made it one of the highest performing and most desired middle schools in Boston, dramatically narrowing and even eliminating academic achievement gaps while delivering a far more well-rounded education to its…

  12. Phase reference VLBI astrometry fro Mira-type stars

    NASA Astrophysics Data System (ADS)

    Hachisuka, Kazuya; Miyoshi, Makoto

    2003-04-01

    We carried out phase reference VLBI observations at 43 GHz between SiO masers in Mira type variables and adjacent extragalactic continuum source with VLBA. Main aim of this obervation is determination of spatial distribution between SiO maser spots at υ=1 and υ=2, J=1→0 transition. Although the standard calibration was successful for each source, the phase reference calibration have not been successful. However, we will determine the absolute positional difference of each SiO maser spot within about 1 milliarcsecond due to the structure effect of reference source if the phase reference VLBI is successful.

  13. A new approach to the analysis of Mira light curves

    NASA Technical Reports Server (NTRS)

    Mennessier, M. O.; Barthes, D.; Mattei, J. A.

    1990-01-01

    Two different but complementary methods for predicting Mira luminosities are presented. One method is derived from a Fourier analysis, it requires performing deconvolution, and its results are not certain due to the inherent instability of deconvolution problems. The other method is a learning method utilizing artificial intelligence techniques where a light curve is presented as an ordered sequence of pseudocycles, and rules are learned by linking the characteristics of several consecutive pseudocycles to one characteristic of the future cycle. It is observed that agreement between these methods is obtainable when it is possible to eliminate similar false frequencies from the preliminary power spectrum and to improve the degree of confidence in the rules.

  14. Vorticity dynamics of a bileaflet mechanical heart valve in an axisymmetric aorta

    NASA Astrophysics Data System (ADS)

    Dasi, L. P.; Ge, L.; Simon, H. A.; Sotiropoulos, F.; Yoganathan, A. P.

    2007-06-01

    We present comprehensive particle image velocimetry measurements and direct numerical simulation (DNS) of physiological, pulsatile flow through a clinical quality bileaflet mechanical heart valve mounted in an idealized axisymmetric aorta geometry with a sudden expansion modeling the aortic sinus region. Instantaneous and ensemble-averaged velocity measurements as well as the associated statistics of leaflet kinematics are reported and analyzed in tandem to elucidate the structure of the velocity and vorticity fields of the ensuing flow-structure interaction. The measurements reveal that during the first half of the acceleration phase, the flow is laminar and repeatable from cycle to cycle. The valve housing shear layer rolls up into the sinus and begins to extract vorticity of opposite sign from the sinus wall. A start-up vortical structure is shed from the leaflets and is advected downstream as the leaflet shear layers become wavy and oscillatory. In the second half of flow acceleration the leaflet shear layers become unstable and break down into two von Karman-like vortex streets. The onset of vortex shedding from the valve leaflets is responsible for the growth of significant cycle-to-cycle vorticity oscillations. At peak flow, the housing and leaflet shear layers undergo secondary instabilities and break down rapidly into a chaotic, turbulent-like state with multiple small-scale vortical structures emerging in the flow. During the deceleration and closing phases all large-scale coherent flow features disappear and a chaotic small-scale vorticity field emerges, which persists even after the valve has closed. Probability density functions of the leaflet position during opening and closing phases show that the leaflet position fluctuates from cycle to cycle with larger fluctuations evident during valve closure. The DNS is carried out by prescribing the leaflet kinematics from the experimental data. The computed instantaneous vorticity fields are in very good

  15. Annual parallax measurements of a Mira variable star, U Lyncis

    NASA Astrophysics Data System (ADS)

    Kamezaki, Tatsuya; Nakagawa, Akiharu; Omodaka, Toshihiro; Handa, Toshihiro; Inoue, Kan-ichiro; Kurayama, Tomoharu; Kobayashi, Hideyuki; Nagayama, Takumi; Ueno, Yuji

    2016-10-01

    We have measured the annual parallax of the water maser around a Mira star, U Lyncis (U Lyn) with VLBI Exploration of Radio Astrometry (VERA). The value of the parallax is 1.27 ± 0.06 mas, corresponding to a distance of 786^{+40}_{-36}pc. This is the first VLBI measurement of the parallax of U Lyn. We obtained the period and the apparent magnitude of U Lyn based on near-infrared observations with the Kagoshima University 1 m telescope. The period and the mean magnitude of the K' band are 437.9 day and +1.15 ± 0.09 mag, respectively. Using our measured parallax and period, we find that the location of U Lyn on the period-luminosity plane is consistent with its nature as a Mira variable fundamental mode pulsator. Also, we estimated the distance using the period-luminosity relationship, our period and apparent magnitude and this gave a difference of about 100 pc between our parallactic distance and the distance estimated by using the period-luminosity relationship. We estimated the luminosity, radius, and mass of U Lyn to be 10100 ± 420 L⊙, 391 ± 34 R⊙, and 1.9 ± 0.7 M⊙, respectively. We found 50 water maser spots with a distribution ˜ 13 au around the star and the motion implies the existence of an outflow.

  16. Annual parallax measurements of a Mira variable star, U Lyncis

    NASA Astrophysics Data System (ADS)

    Kamezaki, Tatsuya; Nakagawa, Akiharu; Omodaka, Toshihiro; Handa, Toshihiro; Inoue, Kan-ichiro; Kurayama, Tomoharu; Kobayashi, Hideyuki; Nagayama, Takumi; Ueno, Yuji

    2015-06-01

    We have measured the annual parallax of the water maser around a Mira star, U Lyncis (U Lyn) with VLBI Exploration of Radio Astrometry (VERA). The value of the parallax is 1.27 ± 0.06 mas, corresponding to a distance of 786^{+40}_{-36}pc. This is the first VLBI measurement of the parallax of U Lyn. We obtained the period and the apparent magnitude of U Lyn based on near-infrared observations with the Kagoshima University 1 m telescope. The period and the mean magnitude of the K' band are 437.9 day and +1.15 ± 0.09 mag, respectively. Using our measured parallax and period, we find that the location of U Lyn on the period-luminosity plane is consistent with its nature as a Mira variable fundamental mode pulsator. Also, we estimated the distance using the period-luminosity relationship, our period and apparent magnitude and this gave a difference of about 100 pc between our parallactic distance and the distance estimated by using the period-luminosity relationship. We estimated the luminosity, radius, and mass of U Lyn to be 10100 ± 420 L⊙, 391 ± 34 R⊙, and 1.9 ± 0.7 M⊙, respectively. We found 50 water maser spots with a distribution ˜ 13 au around the star and the motion implies the existence of an outflow.

  17. A biomimetic bi-leaflet mitral prosthesis with enhanced physiological left ventricular swirl restorative capability

    NASA Astrophysics Data System (ADS)

    Tan, Sean Guo-Dong; Kim, Sangho; Leo, Hwa Liang

    2016-06-01

    Mechanical heart valve prostheses are often implanted in young patients due to their durability and long-term reliability. However, existing designs are known to induce elevated levels of blood damage and blood platelet activation. As a result, there is a need for patients to undergo chronic anti-coagulation treatment to prevent thrombosis, often resulting in bleeding complications. Furthermore, recent studies have suggested that the implantation of a mechanical prosthetic valve at the mitral position results in a significant alteration of the left ventricular flow field which may contribute to flow turbulence. This study proposes a bi-leaflet mechanical heart valve design (Bio-MHV) that mimics the geometry of a human mitral valve, with the aim of reducing turbulence levels in the left ventricle by replicating physiological flow patterns. An in vitro three-dimensional particle velocimetry imaging experiment was carried out to compare the hemodynamic performance of the Bio-MHV with that of the clinically established ATS valve. The Bio-MHV was found to replicate physiological left ventricular flow patterns and produced lower turbulence levels.

  18. A numerical investigation of blood damage in the hinge area of bileaflet mechanical heart valves

    NASA Astrophysics Data System (ADS)

    Yun, Min; Wu, Jingshu; Simon, Helene; Sotiropoulos, Fotis; Aidun, Cyrus; Yoganathan, Ajit

    2010-11-01

    Studies have shown that high shear stress and large recirculation regions have a strong impact on thromboembolic complications in Bileaflet mechanical heart valves (BMHV). This study quantitatively compares the hinge flow field and blood damage of the 23mm St. Jude Medical (SJM) regent with different hinge gap widths and the 23mm CarboMedics (CM) valves. The lattice-Boltzmann method with external boundary force (LBM-EBF) [Wu and Aidun, Int. J Num. Methods Fluids, 62, 7, 2009] was implemented to simulate the flow and capture the dynamics and the surface shear stress of the platelets with realistic geometry. The velocity boundary conditions for the small-scale hinge flow are obtained from previous 3D large-scale computational fluid dynamics (CFD) simulations [Simon et al, Annals of Biomedical Engineering, 38, 3, 2009]. The flow patterns of three hinges that were studied were similar during diastole. However, velocity magnitudes and shear stresses at the hinge gap were different, which may explain the higher blood damage index (BDI) value for the CM valve and lower BDI value for the SJM valve with a larger gap width. The multiscale computational method used to quantitatively measure the BDI during a full cardiac cycle will be discussed.

  19. Manipulation of the closing transients of bileaflet mechanical heart valves using passive, surface-mounted elements

    NASA Astrophysics Data System (ADS)

    Simon, Helene

    2005-11-01

    The time-periodic closing of bileaflet mechanical heart valves is accompanied by a strong flow transient that is associated with the formation of a counter-rotating vortex pair near the b-datum line of leaflet edges. The strong transitory shear that is generated by these vortices may be damaging to blood elements and may result in platelet activation. In the present work, these flow transients are mitigated using miniature vortex generator arrays that are embedded on the surface of the leaflets. The closing transients in the absence and presence of the passive vortex generators are characterized using PIV measurements that are phase locked to the leaflet motion. The study utilizes a 25 mm St. Jude Medical valve placed in the aortic position of the Georgia Tech left heart simulator. The valve is subjected to physiological flow conditions: a heart rate of 70 bpm; a cardiac output of 5 l/min; and a mean aortic pressure of 90 mmHg. Measurements of the velocity field in the center plane of the leaflets demonstrate that the dynamics of the transient vortices that precede the formation of the leakage jets can be significantly altered and controlled by relatively simple passive modifications of existing valve designs.

  20. Effect of vortex generators on the closing transient flow of bileaflet mechanical heart valves

    NASA Astrophysics Data System (ADS)

    Murphy, David; Dasi, Lakshmi; Yoganathan, Ajit; Glezer, Ari

    2006-11-01

    The time-periodic closing of bileaflet mechanical heart valves is accompanied by a strong flow transient that is associated with the formation of a counter-rotating vortex pair near the b-datum line of leaflet edges. The strong transitory shear that is generated by these vortices may be damaging to blood elements and may result in platelet activation. In the present work, these flow transients are mitigated using miniature vortex generator arrays that are embedded on the surface of the leaflets. Two vortex generator designs were investigated: one design comprised staggered rectangular fins and the other one staggered hemispheres. The closing transients in the absence and presence of the passive vortex generators are characterized using phase locked PIV measurements. The study utilizes a 25 mm St. Jude Medical valve placed in the aortic position of the Georgia Tech left heart simulator. Measurements of the velocity field in the center plane of the leaflets demonstrate that the dynamics of the transient vortices that precede the formation of the leakage jets can be significantly altered and controlled by relatively simple passive modifications of existing valve designs. Human blood experiments validated the effectiveness of miniature vortex generators in reducing thrombus formation by over 42 percent.

  1. Numerical Investigation of the Performance of Three Hinge Designs of Bileaflet Mechanical Heart Valves

    PubMed Central

    Simon, Hélène A.; Ge, Liang; Sotiropoulos, Fotis

    2010-01-01

    Thromboembolic complications (TECs) of bileaflet mechanical heart valves (BMHVs) are believed to be due to the nonphysiologic mechanical stresses imposed on blood elements by the hinge flows. Relating hinge flow features to design features is, therefore, essential to ultimately design BMHVs with lower TEC rates. This study aims at simulating the pulsatile three-dimensional hinge flows of three BMHVs and estimating the TEC potential associated with each hinge design. Hinge geometries are constructed from micro-computed tomography scans of BMHVs. Simulations are conducted using a Cartesian sharp-interface immersed-boundary methodology combined with a second-order accurate fractional-step method. Leaflet motion and flow boundary conditions are extracted from fluid–structure-interaction simulations of BMHV bulk flow. The numerical results are analyzed using a particle-tracking approach coupled with existing blood damage models. The gap width and, more importantly, the shape of the recess and leaflet are found to impact the flow distribution and TEC potential. Smooth, streamlined surfaces appear to be more favorable than sharp corners or sudden shape transitions. The developed framework will enable pragmatic and cost-efficient preclinical evaluation of BMHV prototypes prior to valve manufacturing. Application to a wide range of hinges with varying design parameters will eventually help in determining the optimal hinge design. PMID:20571852

  2. Development of a polymer bileaflet valve to realize a low-cost pulsatile blood pump.

    PubMed

    Iwasaki, Kiyotaka; Umezu, Mitsuo; Iijima, Kazuo; Inoue, Akira; Imachi, Kou; Ye, Chun Xiu

    2003-01-01

    The final goal of this study is to realize a low-cost pulsatile blood pump especially for patients with acute heart failure or postoperative low cardiac output syndrome. In support of the pump, two types of polymer bileaflet valves with different configuration of the valve seats were developed. Influence of the leaflet thickness on the hydrodynamics of the prototype was preliminarily investigated among 70 microm, 100 microm, and 150 microm. As to the valves with the thinner leaflets, buckling of the leaflets was observed, which induced a large amount of regurgitation at valve closure. However, by thickening the leaflet to 150 microm, the mean flow of the prototype and the second model could be successfully comparable to the Medtronic-Hall valve. Moreover, accelerated fatigue tests showed that reinforcement of the valve seat with the additional spokes in the second model extended the durability by four times as compared with the prototype, equivalent to an in vivo duration of over one month. PMID:12534717

  3. Mitigation of Shear-Induced Blood Damage of Mechanical Bileaflet Heart Valves using Embedded Vortex Generators

    NASA Astrophysics Data System (ADS)

    Hidalgo, Pablo; Arjunon, Sivakkumar; Saikrishnan, Neelakantan; Yoganathan, Ajit; Glezer, Ari

    2012-11-01

    The strong transitory shear stress generated during the time-periodic closing of the mechanical prosthetic bileaflet aortic heart valve, is considered to be one of the main factors responsible for complications, associated with thrombosis and thromboembolism. These flow transients are investigated using phase and time-averaged PIV in a low-volume (about 150 ml) test setup that simulates the pulsatile physiological conditions associated with a 23 mm St. Jude Medical valve. The PIV measurements are accompanied by continuous monitoring of the ventricular and aortic pressures and valve flow rate. Following the valve closure, the leakage flow between the valve leaflets is caused by the pressure buildup across the leaflets, leading to the formation of a regurgitation jet starting from the BMHV B-datum line. As in a typical starting jet, a counter-rotating vortex pair is formed along each leaflet edge and the vorticity sheet is associated with high shear stress that may be result in blood platelet activation. The present investigation demonstrates that the placement of arrays of mm-scale vortex generators near the edges of the leaflets diffuses the vortex sheet and suppresses the formation of these vortices, weakening the local velocity gradients and small-scale vortical structures. Supported by NIH and NSF.

  4. Laser Doppler anemometry measurements of steady flow through two bi-leaflet prosthetic heart valves

    PubMed Central

    Bazan, Ovandir; Ortiz, Jayme Pinto; Vieira Junior, Francisco Ubaldo; Vieira, Reinaldo Wilson; Antunes, Nilson; Tabacow, Fabio Bittencourt Dutra; Costa, Eduardo Tavares; Petrucci Junior, Orlando

    2013-01-01

    Introduction In vitro hydrodynamic characterization of prosthetic heart valves provides important information regarding their operation, especially if performed by noninvasive techniques of anemometry. Once velocity profiles for each valve are provided, it is possible to compare them in terms of hydrodynamic performance. In this first experimental study using laser doppler anemometry with mechanical valves, the simulations were performed at a steady flow workbench. Objective To compare unidimensional velocity profiles at the central plane of two bi-leaflet aortic prosthesis from St. Jude (AGN 21 - 751 and 21 AJ - 501 models) exposed to a steady flow regime, on four distinct sections, three downstream and one upstream. Methods To provide similar conditions for the flow through each prosthesis by a steady flow workbench (water, flow rate of 17L/min. ) and, for the same sections and sweeps, to obtain the velocity profiles of each heart valve by unidimensional measurements. Results It was found that higher velocities correspond to the prosthesis with smaller inner diameter and instabilities of flow are larger as the section of interest is closer to the valve. Regions of recirculation, stagnation of flow, low pressure, and flow peak velocities were also found. Conclusions Considering the hydrodynamic aspect and for every section measured, it could be concluded that the prosthesis model AGN 21 - 751 (RegentTM) is superior to the 21 AJ - 501 model (Master Series). Based on the results, future studies can choose to focus on specific regions of the these valves. PMID:24598950

  5. RECONCILING THE EMISSION MECHANISM DISCREPANCY IN MIRA'S TAIL AND ITS EVOLUTION IN AN INTERFACE WITH SHEAR

    SciTech Connect

    Wareing, C. J.

    2012-04-01

    Galaxy Evolution Explorer observations of the Mira AB binary system revealed a surrounding structure that has been successfully hydrodynamically interpreted as a bow shock and tail of ram-pressure-stripped material. Even the narrow tail, initially difficult to model, has been understood to be the effect of the passage of Mira from a warm neutral medium into a hot, low-density medium, postulated to be the Local Bubble. However, no model to date has explained the observed kink and associated general curvature of the tail. We test the hypothesis that before entering the Local Bubble, Mira was traveling through a shear flow with approximately 1/3 Mira's own velocity at an angle of 30 Degree-Sign to Mira's proper motion. The hypothesis reproduces the kinked nature of Mira's tail and predicts recompression and reheating of the tail material to the same or greater levels of density and temperature predicted in the shock. This provides a heat source for the FUV emission, allowing for an extended lifetime of the FUV emission in line with other estimates of the age of the tail. The uniqueness of Mira's situation implies that the chances of observing other FUV tails behind asymptotic giant branch stars are highly unlikely.

  6. Star GK Bileaflet Mechanical Valve Prosthesis-Patient Mismatch After Mitral Valve Replacement: A Chinese Multicenter Clinical Study

    PubMed Central

    Cao, Hua; Qiu, Zhihuang; Chen, Liangwan; Chen, Daozhong; Chen, Qiang

    2015-01-01

    Background The aim of this study was to investigate the incidence and immediate and mid-term effects of heart valve prosthesis-patient mismatch (PPM) after mitral valve replacement using the GK bileaflet mechanical valve. Material/Methods A total of 493 cases of mechanical mitral valve replacement were performed in the departments of cardiac surgery in 7 hospitals from January 2000 to January 2008. The patients included 142 men and 351 women ages 21 to 67 (average age, 48.75). The patients were followed for 3 years after surgery. The effective orifice area index (EOAI), ≤1.2 cm2/m2, was detected during the follow-up period and was defined as PPM. The patients were assigned to either the PPM group or the non-PPM group. Finally, the preoperative, perioperative and postoperative indexes of the 2 groups of patients were compared. Results A total of 157 patients had PPM 3 years after surgery. The incidence of PPM was 31.84%. Sixty-three patients in the PPM group received a 25-mm GK bileaflet valve (40.13%), 82 received a 27-mm valve (52.23%), and 12 (7.64%) received a 29-mm valve. There were significant differences in length of intensive care unit stay, duration of ventilator use, length of hospitalization, body surface area, EOAI, mean transmitral pressure gradient, and pulmonary artery pressure between the PPM and non-PPM group (P<0.05). There was a significant difference between preoperative and postoperative pulmonary artery pressures among non-PPM patients (P<0.05); however, there was no statistical difference in preoperative and postoperative pulmonary artery pressures among patients with PPM (P>0.05). Conclusions PPM after mitral valve replacement influences postoperative hemodynamics. Thus, larger-sized GK bileaflet mechanical valves are often used to reduce the risk of PPM. PMID:26313311

  7. Brenda K. Edwards, PhD

    Cancer.gov

    Brenda K. Edwards, PhD, has been with the Surveillance Research Program (SRP) and its predecessor organizations at the National Cancer Institute (NCI) since 1989, serving as SRP’s Associate Director from 1990-2011.

  8. Sturckow Recaps Last Shuttle Landing at Edwards

    NASA Video Gallery

    When Space Shuttle Discovery touched down at Edwards Air Force Base in Southern California on Sept. 11, 2009 to conclude mission STS-128, no one foresaw that it would be the last of 54 such landing...

  9. Edward Wheeler Hones Jr. (1922-2012)

    NASA Astrophysics Data System (ADS)

    Baker, Daniel N.; McPherron, Robert L.; Birn, Joachim

    2013-02-01

    Space physicist Edward Wheeler Hones Jr. died on 17 September 2012 at his home in Los Alamos, N. M. He was 90 years old. The cause of death was a heart attack that came following a brief hospitalization.

  10. First Assessment of the MIRAS In-Orbit Instrument Verification

    NASA Astrophysics Data System (ADS)

    Closa, Josep; Benito, Javier; Bergada, Marc; Borges, Andres; Cortes, David; Garcia, Quiterio; Olea, Ana; Lamela, Felix; Rubiales, Pilar; Sancho, Luisa; Sanz, Juan Andres; Solana, Andres; Martin-Neira, Mannuel

    2010-12-01

    The Microwave Imaging Radiometer using Aperture Synthesis (MIRAS) is the sole payload of the SMOS satellite launched on 2nd November 2009 from the Plesetsk Cosmodrome. Instrument capabilities allow observation in different modes (DUAL polarization and FULL polarization) as well as internal calibration through correlated and uncorrelated noise injection. Developed by EADS-CASA Espacio as prime contractor under ESA contract, the instrument was under intensive on-ground testing prior to the launch and was verified during the first six months after switch on, the so-called Commissioning Phase. This paper details the first results of the in-orbit instrument verification, from instrument performance assessment of the different modes, including those devoted to calibration and a review of the mission requirements to the optimization of the instrument commanding in order to improve product quality.

  11. Vanadium Oxide in the Spectra of Mira Variables

    NASA Astrophysics Data System (ADS)

    Castelaz, M. W.; Luttermoser, D. G.; Piontek, R. A.

    1999-05-01

    Over the last three years, we have made spectroscopic measurements of twenty Mira variable stars, as a function of phase, probing their stellar atmospheres and underlying pulsation mechanisms. Measurement of variations in TiO and VO with phase can be used to help determine whether these molecular species are produced in an extended region above the layers where Balmer line emission occurs or below this shocked region. Piontek & Luttermoser (1999 IAPPPC, submitted), produce synthetic spectra for three Mira variables, R Leo, V CVn, and R CVn as a function of phase. Comparison of their synthetic spectra to our observed spectra yield the fundamental astrophysical parameters of effective temperatures and surface gravities. Spectra are synthesized with LTE stellar stmospheres code ATLAS, using the 6.6--million Indiana University atomic and molecular line dataset. Piontek & Luttermoser point out that the IU dataset does not include vanadium oxide (VO). Thus, there is a noticeable difference between the synthetic spectra and observed near-IR spectra corresponding to the B-X bands of VO (Mahanti 1935, Proc. Phys. Soc., 47, 43; Keenan & Schroeder 1952,L. W., ApJ, 115, 82). In order to incorporate the VO bands in the synthetic spectra, we need to establish tables of wavenumbers, lowest energy levels, and oscillator strengths. Producing the tables is non-trivial. Laboratory measurements of wavenumbers are used in the Just-Overlapping Line Approximation (JOLA; Tsuji 1966, PASJ, 18, 127) to calculate oscillator strengths. The JOLA technique and preliminary results will be presented. MWC greatly appreciates support from the National Science Foundation grant AST-9500756. RAP acknowledges the Southeastern Association for Research in Astronomy 1998 Summer REU program supported by the National Science Foundation and thanks DGL for being his mentor.

  12. STS-66 Edwards Landing Approach

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The space shuttle Atlantis approaches runway 22 at Edwards, California, to complete the STS-66 mission dedicated to the third flight of the Atmospheric Laboratory for Applications and Science-3 (ATLAS-3), part of NASA's Mission to Planet Earth program. The astronauts also deployed and retrieved a free-flying satellite designed to study the middle and lower thermospheres and perform a series of experiments covering life sciences research and microgravity processing. The landing was at 7:34 a.m. (PST) 14 November 1994, after being waved off from the Kennedy Space Center, Florida, due to adverse weather. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout the mission. They are then removed after the Space Shuttle returns to Earth and can be reused on

  13. The Application of Bileaflet Mechanical Heart Valves in the Polish Ventricular Assist Device: Physical and Numerical Study and First Clinical Usage.

    PubMed

    Malota, Zbigniew; Sadowski, Wojciech; Krzyskow, Marek; Stolarzewicz, Bogdan

    2016-03-01

    The Polish ventricular assist device (Polvad) has been used successfully in clinical contexts for many years. The device contains two single-disc valves, one at the inlet and one at the outlet connector of the pneumatic pump. Unfortunately, in recent years, a problem has occurred with the availability of single-disc valves. This article presents the possibility of using bileaflet mechanical heart valve prostheses in the Polvad to avoid a discontinuity in clinical use. The study is based on experimental and numerical simulations and comparison of the distribution of flow, pressure, and stress (wall, shear, and turbulent) inside the Polvad chamber and the inlet/outlet connectors fitted with Sorin Monodisc and Sorin Bicarbon Fitline valves. The type and orientation of the inlet valve affects valve performance and flow distribution inside the chamber. Near-wall flow is observed for single-disc valves. In the case of bileaflet valves, the main jet is directed more centrally, with lower shear stress but higher turbulent stress in comparison with single-disc valves. For clinical usage, a 45° orientation of the bileaflet inlet valve was chosen, as this achieves good washing of the inlet area near the membrane paste surface. The Polvad with bileaflet valves has now been used successfully in our clinic for over a year and will continue to be used until new assist devices for heart support are developed.

  14. DISCOVERY OF MIRA VARIABLE STARS IN THE METAL-POOR SEXTANS DWARF SPHEROIDAL GALAXY

    SciTech Connect

    Sakamoto, Tsuyoshi; Matsunaga, Noriyuki; Nakada, Yoshikazu; Hasegawa, Takashi

    2012-12-10

    We report the discovery of two Mira variable stars (Miras) toward the Sextans dwarf spheroidal galaxy (dSph). We performed optical long-term monitoring observations for two red stars in the Sextans dSph. The light curves of both stars in the I{sub c} band show large-amplitude (3.7 and 0.9 mag) and long-period (326 {+-} 15 and 122 {+-} 5 days) variations, suggesting that they are Miras. We combine our own infrared data with previously published data to estimate the mean infrared magnitudes. The distances obtained from the period-luminosity relation of the Miras (75.3{sup +12.8}{sub -10.9} and 79.8{sup +11.5}{sub -9.9} kpc, respectively), together with the radial velocities available, support memberships of the Sextans dSph (90.0 {+-} 10.0 kpc). These are the first Miras found in a stellar system with a metallicity as low as [Fe/H] {approx} -1.9 than any other known system with Miras.

  15. STS-68 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The space shuttle Endeavour glides to a landing on runway 22 at Edwards, California, to complete the highly successful STS-68 mission dedicated to radar imaging of the earth's surface as part of NASA's Mission To Planet Earth program. The landing was at 10:02 a.m. (PDT) 11 October 1994, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather at Kennedy. The Endeavour crew was originally scheduled to land at Kennedy the morning of October 10, but mission planners decided early in the flight to extend the mission by one day. Mission commander was Michael A. Baker, making his third flight, and the pilot was Terrence W. Wilcutt, on his first mission. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout the

  16. STS-66 Edwards Landing Approach

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The space shuttle Atlantis approaches runway 22 at Edwards, California, to complete the STS-66 mission dedicated to the third flight of the Atmospheric Laboratory for Applications and Science-3 (ATLAS-3), part of NASA's Mission to Planet Earth program. The astronauts also deployed and retrieved a free-flying satellite designed to study the middle and lower thermospheres and perform a series of experiments covering life sciences research and microgravity processing. The landing was at 7:34 a.m. (PST) 14 November 1994, after being waved off from the Kennedy Space Center, Florida, due to adverse weather. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout the mission. They are then removed after the Space Shuttle returns to Earth and can be reused on

  17. STS-68 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    A drag chute slows the shuttle Endeavour after landing on runway 22 at Edwards, California, to complete the highly successful STS-68 mission dedicated to radar imaging of the earth's surface as part of NASA's Mission To Planet Earth program. The landing was at 10:02 a.m. (PDT) 11 October 1994, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather at Kennedy. The Endeavour crew was originally scheduled to land at Kennedy the morning of 10 October, but mission planners decided early in the flight to extend the mission by one day. Mission commander was Michael A. Baker and the pilot was Terrence W. Wilcutt. The four mission specialists were Thomas D. Jones, payload; Steven L. Smith; Daniel W. Bursch; and Peter J.K. Wisoff. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific

  18. STS-68 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The shuttle Endeavour comes in for a landing on runway 22 at Edwards, California, to complete the highly successful STS-68 mission dedicated to radar imaging of the earth's surface as part of NASA's Mission To Planet Earth program. The landing was at 10:02 a.m. (PDT) 11 October 1994, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather at Kennedy. The Endeavour crew was originally scheduled to land at Kennedy the morning of 10 October, but mission planners decided early in the flight to extend the mission by one day. Mission commander was Michael A. Baker making his third flight and the pilot was Terrence W. Wilcutt on his first mission. The four mission specialists were Thomas D. Jones, payload commander making his second flight; Steven L. Smith on his first flight; Daniel W. Bursch making his second flight; and Peter J.K. Wisoff making his second flight. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only

  19. STS-68 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The space shuttle Endeavour glides to a landing on runway 22 at Edwards, California, to complete the highly successful STS-68 mission dedicated to radar imaging of the earth's surface as part of NASA's Mission To Planet Earth program. The landing was at 10:02 a.m. (PDT) 11 October 1994, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather at Kennedy. The Endeavour crew was originally scheduled to land at Kennedy the morning of October 10, but mission planners decided early in the flight to extend the mission by one day. Mission commander was Michael A. Baker, making his third flight, and the pilot was Terrence W. Wilcutt, on his first mission. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout the

  20. STS-64 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The Space Shuttle Discovery settles to the main runway at Edwards, California, at 2:13 p.m. (PDT) 20 September 1994, to conclude mission STS-64. The spacecraft, with a crew of six, was launched into a 57-degree high inclination orbit from the Kennedy Space Center, Florida, at 3:23 p.m. (PDT), 9 September 1994. The mission featured the study of clouds and the atmosphere with a laser beaming system called Lidar In-Space Technology Experiment (LITE), and the first untethered space walk in over ten years. A Spartan satellite was also deployed and later retrieved in the study of the sun's corona and the solar wind. The mission was scheduled to end Sunday, 18 September, but was extended one day to continue science work. Bad weather at the Kennedy Space Center on September 19, forced a one-day delay to September 20, with a weather divert that day to Edwards. Mission commander was Richard Richards, the pilot Blaine Hammond, while mission specialists were Jerry Linenger, Susan Helms, Carl Meade, and Mark Lee. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders

  1. Shuttle Discovery Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The STS-29 Space Shuttle Discovery mission lands at NASA's then Ames-Dryden Flight Research Facility, Edwards AFB, California, early Saturday morning, 18 March 1989. Touchdown was at 6:35:49 a.m. PST and wheel stop was at 6:36:40 a.m. on runway 22. Controllers chose the concrete runway for the landing in order to make tests of braking and nosewheel steering. The STS-29 mission was very successful, completing the launch of a Tracking and Data Relay communications satellite, as well as a range of scientific experiments. Discovery's five-man crew was led by Commander Michael L. Coats, and included pilot John E. Blaha and mission specialists James P. Bagian, Robert C. Springer, and James F. Buchli. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout

  2. 7. DETAIL, ANCHOR FIXTURES. Looking to north. Edwards Air ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. DETAIL, ANCHOR FIXTURES. Looking to north. - Edwards Air Force Base, South Base Sled Track, Edwards Air Force Base, North of Avenue B, between 100th & 140th Streets East, Lancaster, Los Angeles County, CA

  3. In Tribute: Senator Edward M. Kennedy, Friend of NIH

    MedlinePlus

    ... Javascript on. In Tribute: Senator Edward M. Kennedy, Friend of NIH Past Issues / Fall 2009 Table of ... NICHD) in Shriver's honor. Senator Edward M. Kennedy, Friend of NIH "… deep compassion for those in need." ...

  4. Prince Edward Island. Reference Series No. 33.

    ERIC Educational Resources Information Center

    Department of External Affairs, Ottawa (Ontario).

    This booklet, one of a series featuring the Canadian provinces, presents a brief overview of Prince Edward Island and is suitable for teacher reference or student reading. Separate sections discuss geography, climate, history, early trade, development, agriculture, the potato industry, forests, fisheries, aquaculture, industry, tourism, energy,…

  5. Edward Weston and the "Modern" Galvanometer Movement

    ERIC Educational Resources Information Center

    Greenslade, Thomas B., Jr.

    2008-01-01

    One of my favorite 19th century electrical scientists is Edward Weston, and one of my favorite devices for teaching the topics of electromagnetic forces and torques is the D'Arsonval galvanometer. The junction of these two topics is Weston's improved meter movement that has been used in analog meters for the past 125 years.

  6. Prince Edward Island's School Psychology Report

    ERIC Educational Resources Information Center

    Matters, Rhonda

    2016-01-01

    The Prince Edward Island (PEI) school system has been struggling with issues of recruitment and particularly retention for psychologists. Reasons include concerns about professional autonomy; having more limited roles, which are heavily assessment focused; reduced job satisfaction; and restrictions on additional private practice work. The waiting…

  7. STS-68 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    A drag chute slows the shuttle Endeavour after landing on runway 22 at Edwards, California, to complete the highly successful STS-68 mission dedicated to radar imaging of the earth's surface as part of NASA's Mission To Planet Earth program. The landing was at 10:02 a.m. (PDT) 11 October 1994, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather at Kennedy. The Endeavour crew was originally scheduled to land at Kennedy the morning of 10 October, but mission planners decided early in the flight to extend the mission by one day. Mission commander was Michael A. Baker and the pilot was Terrence W. Wilcutt. The four mission specialists were Thomas D. Jones, payload; Steven L. Smith; Daniel W. Bursch; and Peter J.K. Wisoff. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific

  8. STS-68 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The shuttle Endeavour comes in for a landing on runway 22 at Edwards, California, to complete the highly successful STS-68 mission dedicated to radar imaging of the earth's surface as part of NASA's Mission To Planet Earth program. The landing was at 10:02 a.m. (PDT) 11 October 1994, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather at Kennedy. The Endeavour crew was originally scheduled to land at Kennedy the morning of 10 October, but mission planners decided early in the flight to extend the mission by one day. Mission commander was Michael A. Baker making his third flight and the pilot was Terrence W. Wilcutt on his first mission. The four mission specialists were Thomas D. Jones, payload commander making his second flight; Steven L. Smith on his first flight; Daniel W. Bursch making his second flight; and Peter J.K. Wisoff making his second flight. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only

  9. Shuttle Atlantis Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1985-01-01

    NASA's Space Shuttle Atlantis touched down on the lakebed runway at Edwards Air Force Base in California's Mojave Desert Tuesday, 3 December 1985 at 1:33:49 p.m. Pacific Standard Time, concluding the STS 61-B international mission. The eight-day mission successfully deployed three communications satellites including the Mexican Morelos B, the Australian Aussat 2 and an RCA Satcom K-2 satellite. In addition, two spacewalks were performed to experiment with construction of structures in space. Crew of the 61-B mission included Commander Brewster H. Shaw, Jr.; Pilot Bryan D. O'Connor; Mission Specialists Mary L. Cleave, Sherwood C. Spring and Jerry L. Ross; and Payload Specialists Rudolfo Neri Vela of Mexico and Charles Walker of McDonnell Douglas Astronautics Co. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories

  10. STS-40 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Space Shuttle Columbia nears its touchdown on Runway 22 at Edwards, California, at 8:39 a.m., 14 June 1991, as the STS-40 life sciences mission comes to an end at NASA's Ames-Dryden Flight Research Facility (later redesignated Dryden Flight Research Center) after nine days of orbital flight. Aboard Columbia during the extended mission were Bryan D. O'Connor, mission commander; Sidney M. Gutierrez, pilot; mission specialists James P. Bagian, Tamara E. Jernigan, and Margaret Rhea Seddon; and payload specialists Francis Andrew Gaffney and Millie Hughes-Fulford. STS-40 was the first space shuttle mission dedicated to life sciences research to explore how the body reacts to a weightless environment and how it readjusts to gravity on return to earth. Columbia was launched on the STS-40 mission 5 June 1991, from Kennedy Space Center in Florida. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused

  11. Shuttle Atlantis Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1988-01-01

    , provide facilities for several specialists to conduct experiments in such fields as medicine, astronomy, and materials manufacturing. Some types of satellites deployed by Space Shuttles include those involved in environmental and resources protection, astronomy, weather forecasting, navigation, oceanographic studies, and other scientific fields. The Space Shuttles can also launch spacecraft into orbits higher than the Shuttle's altitude limit through the use of Inertial Upper Stage (IUS) propulsion units. After release from the Space Shuttle payload bay, the IUS is ignited to carry the spacecraft into deep space. The Space Shuttles are also being used to carry elements of the International Space Station into space where they are assembled in orbit. The Space Shuttles were built by Rockwell International's Space Transportation Systems Division, Downey, California. Rockwell's Rocketdyne Division (now part of Boeing) builds the three main engines, and Thiokol, Brigham City, Utah, makes the solid rocket booster motors. Martin Marietta Corporation (now Lockheed Martin), New Orleans, Louisiana, makes the external tanks. Each orbiter (Space Shuttle) is 121 feet long, has a wingspan of 78 feet, and a height of 57 feet. The Space Shuttle is approximately the size of a DC-9 commercial airliner and can carry a payload of 65,000 pounds into orbit. The payload bay is 60 feet long and 15 feet in diameter. Each main engine is capable of producing a sea level thrust of 375,000 pounds and a vacuum (orbital) thrust of 470,000 pounds. The engines burn a mixture of liquid oxygen and liquid hydrogen. In orbit, the Space Shuttles circle the earth at a speed of 17,500 miles per hour with each orbit taking about 90 minutes. A Space Shuttle crew sees a sunrise or sunset every 45 minutes. When Space Shuttle flights began in April 1981, Dryden Flight Research Center, Edwards, California, was the primary landing site for the Shuttles. Now Kennedy Space Center, Florida, is the primary landing site

  12. STS-55 Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Space Shuttle Columbia completes the STS-55 Spacelab D-2 mission 6 May with a landing at NASA's Ames-Dryden Flight Research Facility (later redesignated the Dryden Flight Research Center), Edwards, California, at 7:30 a.m. (PDT). The landing was scheduled for the Kennedy Space Center, Florida, but was diverted to Dryden during the final hours of flight because of unacceptable weather at the Florida facility. The STS-55 mission began with the launch from Kennedy at 7:50 a.m. (PDT), 26 April. Aboard Columbia were commander Steve Nagel; pilot Tom Henricks; mission specialists Jerry Ross, Charles Precourt, and Bernard Harris; and payload specialists Hans Schlegel and Ulrich Walter, both from Germany. During Columbia's flight the NASA space shuttle fleet logged more than one year of combined flight time in space, including the time of all previous orbiters and Columbia on this flight. That mark was reached at 7:01:42 (PDT) on 5 May, and with Columbia's landing the total flight time had reached 365 days, 23 hours, and 28 minutes. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles

  13. A turbulent wake as a tracer of 30,000 years of Mira's mass loss history.

    PubMed

    Martin, D Christopher; Seibert, Mark; Neill, James D; Schiminovich, David; Forster, Karl; Rich, R Michael; Welsh, Barry Y; Madore, Barry F; Wheatley, Jonathan M; Morrissey, Patrick; Barlow, Tom A

    2007-08-16

    Mira is one of the first variable stars ever discovered and it is the prototype (and also the nearest example) of a class of low-to-intermediate-mass stars in the late stages of stellar evolution. These stars are relatively common and they return a large fraction of their original mass to the interstellar medium (ISM) (ref. 2) through a processed, dusty, molecular wind. Thus stars in Mira's stage of evolution have a direct impact on subsequent star and planet formation in their host galaxy. Previously, the only direct observation of the interaction between Mira-type stellar winds and the ISM was in the infrared. Here we report the discovery of an ultraviolet-emitting bow shock and turbulent wake extending over 2 degrees on the sky, arising from Mira's large space velocity and the interaction between its wind and the ISM. The wake is visible only in the far ultraviolet and is consistent with an unusual emission mechanism whereby molecular hydrogen is excited by turbulent mixing of cool molecular gas and shock-heated gas. This wind wake is a tracer of the past 30,000 years of Mira's mass-loss history and provides an excellent laboratory for studying turbulent stellar wind-ISM interactions. PMID:17700694

  14. A turbulent wake as a tracer of 30,000 years of Mira's mass loss history.

    PubMed

    Martin, D Christopher; Seibert, Mark; Neill, James D; Schiminovich, David; Forster, Karl; Rich, R Michael; Welsh, Barry Y; Madore, Barry F; Wheatley, Jonathan M; Morrissey, Patrick; Barlow, Tom A

    2007-08-16

    Mira is one of the first variable stars ever discovered and it is the prototype (and also the nearest example) of a class of low-to-intermediate-mass stars in the late stages of stellar evolution. These stars are relatively common and they return a large fraction of their original mass to the interstellar medium (ISM) (ref. 2) through a processed, dusty, molecular wind. Thus stars in Mira's stage of evolution have a direct impact on subsequent star and planet formation in their host galaxy. Previously, the only direct observation of the interaction between Mira-type stellar winds and the ISM was in the infrared. Here we report the discovery of an ultraviolet-emitting bow shock and turbulent wake extending over 2 degrees on the sky, arising from Mira's large space velocity and the interaction between its wind and the ISM. The wake is visible only in the far ultraviolet and is consistent with an unusual emission mechanism whereby molecular hydrogen is excited by turbulent mixing of cool molecular gas and shock-heated gas. This wind wake is a tracer of the past 30,000 years of Mira's mass-loss history and provides an excellent laboratory for studying turbulent stellar wind-ISM interactions.

  15. Dust around Mira variables: An analysis of IRAS LRS spectra

    NASA Technical Reports Server (NTRS)

    Slijkhuis, S.

    1989-01-01

    The spatial extent and spectral appearance of the thin dust shell around Mira variables is determined largely by the dust absorptivity, Q(sub abs)(lambda), and the dust condensation temperature T(sub cond). Both Q(sub abs)(lambda) and T(sub cond) are extracted from IRAS low-resolution spectra (LRS) spectra. In order to do this, the assumption that the ratio of total power in the 10 micron feature to that in the 20 micron feature should be equal to that measured in other amorphous silicates (e.g., synthesized amorphous Mg2SiO4). It was found that T(sub cond) decreases with decreasing strength of the 10 micron feature, from T(sub cond) = 1000 K to 500 K (estimated error 20 percent). A value for the near-infrared dust absorptivity could not be determined. Although this parameter strongly affects the condensation radius, it hardly affects the shape of the LRS spectrum (as long as the optically thin approximation is valid), because it scales the spatial distribution of the dust. Information on the magnitude of the near-infrared dust absorptivity may be deduced from the unique carbon star BM Gem. This star has a LRS spectrum with silicate features indication an inner dust shell temperature of at least 1000 K. However, on the basis of observations in the 1920s-30s one may infer an inner dust shell radius of at least 6x10(exp 12)m. To have this high temperature at such a large distance, the near-infrared absorptivity of the dust must be high.

  16. VizieR Online Data Catalog: Opacity-sampling models of Mira variables (Ireland+, 2011)

    NASA Astrophysics Data System (ADS)

    Ireland, M. J.; Scholz, M.; Wood, P. R.

    2012-05-01

    We present four model series of the CODEX dynamical opacity-sampling models of Mira variables with solar abundances, designed to have parameters similar to {omicron} Cet, R Leo and R Cas. We demonstrate that the CODEX models provide a clear physical basis for the molecular shell scenario used to explain interferometric observations of Mira variables. We show that these models generally provide a good match to photometry and interferometry at wavelengths between the near-infrared and the radio, and make the model outputs publicly available. These models also demonstrate that, in order to match visible and infrared observations, the Fe-poor silicate grains that form within 3 continuum radii must have small grain radii and therefore cannot drive the winds from O-rich Mira variables. (1 data file).

  17. Edward Teller Returns to LOS Alamos

    NASA Astrophysics Data System (ADS)

    Hecker, Siegfried S.

    2010-01-01

    I was asked to share some reflections of Edward Teller's return to Los Alamos during my directorship. I met Teller late in his life. My comments focus on that time and they will be mostly in the form of stories of my interactions and those of my colleagues with Teller. Although the focus of this symposium is on Teller's contributions to science, at Los Alamos it was never possible to separate Teller's science from policy and controversy ...

  18. 1995 Edward teller lecture. Patience and optimism

    NASA Astrophysics Data System (ADS)

    Miley, George H.

    1996-05-01

    Remarks made in the author's acceptance lecture for the 1995 Edward Teller Medal are presented and expanded. Topics covered include research on nuclear-pumped lasers, the first direct e-beam-pumped laser, direct energy conversion and advanced fuel fusion, plus recent work on inertial electrostatic confinement. ``Patience'' and ``optimism'' are viewed as essential elements needed by scientists following the ``zig-zag'' path to fusion energy production.

  19. Robert Edwards: the path to IVF☆

    PubMed Central

    Johnson, Martin H

    2011-01-01

    The early influences on Robert Edwards’ approach to the scientific research that led to human IVF are described. His interest as a graduate student in the genetics of early mammalian development stimulated him later to investigate whether the origins of human genetic diseases such as Down, Klinefelter and Turner syndromes might be explained by events during egg maturation. This clinical problem provided the most powerful stimulus to achieve both oocyte maturation and fertilization in vitro in humans. Indeed, preimplantation genetic diagnosis was his main goal until he met Patrick Steptoe in 1968. A re-evaluation of his meeting with Steptoe suggests that initially Steptoe’s laparoscopic skill was of interest for its potential to solve the sperm capacitation problem. Steptoe’s impact on Edwards was twofold. First, Steptoe’s long-held interest in infertility raised this application of IVF higher in Edwards’ priorities. Second, Steptoe offered a long-term partnership, in which oocyte collection without in-vitro maturation was a possibility. The professional criticism generated by their work together encouraged Edwards to pursue a deliberate programme of public education about the issues raised and to challenge and develop professional bioethical thought and discourse about reproduction. The early life and career of Robert Edwards are described and re-evaluated in the light of documentary evidence. His early interest in the genetics of development provided the major motivation behind his goal of achieving IVF in humans. Through this work, he aimed to understand and hopefully to reduce the transmission of genetic disease in humans. His meeting with Patrick Steptoe, the details of which are re-examined, increased the significance for Edwards of infertility as an outcome of IVF. It also led to a creative long-term research partnership, initiated a long-term programme of public education in the UK about reproductive science and stimulated the development of

  20. Carbon and Oxygen Isotopic Ratios for Nearby Miras

    NASA Astrophysics Data System (ADS)

    Hinkle, Kenneth H.; Lebzelter, Thomas; Straniero, Oscar

    2016-07-01

    Carbon and oxygen isotopic ratios are reported for a sample of 46 Mira and SRa-type variable asymptotic giant branch (AGB) stars. Vibration-rotation first and second-overtone CO lines in 1.5-2.5 μm spectra were measured to derive isotopic ratios for 12C/13C, 16O/17O, and 16O/18O. Comparisons with previous measurements for individual stars and with various samples of evolved stars, as available in the extant literature, are discussed. Models for solar composition AGB stars of different initial masses are used to interpret our results. We find that the majority of M-stars have main sequence masses ≤2 M ⊙ and have not experienced sizable third dredge-up (TDU) episodes. The progenitors of the four S-type stars in our sample are slightly more massive. Of the six C-stars in the sample three have clear evidence relating their origin to the occurrence of TDU. Comparisons with O-rich presolar grains from AGB stars that lived before the formation of the solar system reveal variations in the interstellar medium chemical composition. The present generation of low-mass AGB stars, as represented by our sample of long period variables (LPVs), shows a large spread of 16O/17O ratios, similar to that of group 1 presolar grains and in agreement with theoretical expectations for the composition of mass 1.2-2 M ⊙ stars after the first dredge-up. In contrast, the 16O/18O ratios of present-day LPVs are definitely smaller than those of group 1 grains. This is most probably a consequence of the the decrease with time of the 16O/18O ratio in the interstellar medium due to the chemical evolution of the Milky Way. One star in our sample has an O composition similar to that of group 2 presolar grains originating in an AGB star undergoing extra-mixing. This may indicate that the extra-mixing process is hampered at high metallicity, or, equivalently, favored at low metallicity. Similarly to O-rich grains, no star in our sample shows evidence of hot bottom burning, which is expected for

  1. Carbon and Oxygen Isotopic Ratios for Nearby Miras

    NASA Astrophysics Data System (ADS)

    Hinkle, Kenneth H.; Lebzelter, Thomas; Straniero, Oscar

    2016-07-01

    Carbon and oxygen isotopic ratios are reported for a sample of 46 Mira and SRa-type variable asymptotic giant branch (AGB) stars. Vibration–rotation first and second-overtone CO lines in 1.5–2.5 μm spectra were measured to derive isotopic ratios for 12C/13C, 16O/17O, and 16O/18O. Comparisons with previous measurements for individual stars and with various samples of evolved stars, as available in the extant literature, are discussed. Models for solar composition AGB stars of different initial masses are used to interpret our results. We find that the majority of M-stars have main sequence masses ≤2 M ⊙ and have not experienced sizable third dredge-up (TDU) episodes. The progenitors of the four S-type stars in our sample are slightly more massive. Of the six C-stars in the sample three have clear evidence relating their origin to the occurrence of TDU. Comparisons with O-rich presolar grains from AGB stars that lived before the formation of the solar system reveal variations in the interstellar medium chemical composition. The present generation of low-mass AGB stars, as represented by our sample of long period variables (LPVs), shows a large spread of 16O/17O ratios, similar to that of group 1 presolar grains and in agreement with theoretical expectations for the composition of mass 1.2–2 M ⊙ stars after the first dredge-up. In contrast, the 16O/18O ratios of present-day LPVs are definitely smaller than those of group 1 grains. This is most probably a consequence of the the decrease with time of the 16O/18O ratio in the interstellar medium due to the chemical evolution of the Milky Way. One star in our sample has an O composition similar to that of group 2 presolar grains originating in an AGB star undergoing extra-mixing. This may indicate that the extra-mixing process is hampered at high metallicity, or, equivalently, favored at low metallicity. Similarly to O-rich grains, no star in our sample shows evidence of hot bottom burning, which is expected

  2. The Chromosphere/Shock Dilemma of Non-Mira, Late-Type Variable Stars

    NASA Technical Reports Server (NTRS)

    Willson, Lee Anne

    1997-01-01

    An investigation of the atmospheric structure of non-Mira, asymptotic giant branch stars through NLTE radiative transfer modeling applied to hydrodynamic models is discussed. Synthetic spectra resulting from these calculations were compared with IUE observations of these stars to test the validity of the models. The development of the hydrodynamic models is detailed.

  3. Are the Current Doppler Echocardiography Criteria Able to Discriminate Mitral Bileaflet Mechanical Heart Valve Malfunction? An In Vitro Study.

    PubMed

    Evin, Morgane; Guivier-Curien, Carine; Pibarot, Philippe; Kadem, Lyes; Rieu, Régis

    2016-05-01

    Malfunction of bileaflet mechanical heart valves in the mitral position could either be due to patient-prosthesis mismatch (PPM) or leaflet obstruction. The aim of this article is to investigate the validity of current echocardiographic criteria used for diagnosis of mitral prosthesis malfunction, namely maximum velocity, mean transvalvular pressure gradient, effective orifice area, and Doppler velocity index. In vitro testing was performed on a double activation left heart duplicator. Both PPM and leaflet obstruction were investigated on a St. Jude Medical Master. PPM was studied by varying the St. Jude prosthesis size (21, 25, and 29 mm) and stroke volume (70 and 90 mL). Prosthesis leaflet obstruction was studied by partially or totally blocking the movement of one valve leaflet. Mitral flow conditions were altered in terms of E/A ratios (0.5, 1.0, and 1.5) to simulate physiologic panel of diastolic function. Maximum velocity, effective orifice area, and Doppler velocity index are shown to be insufficient to distinguish normal from malfunctioning St. Jude prostheses. Doppler velocity index and effective orifice area were 1.3 ± 0.49 and 1.83 ± 0.43 cm(2) for testing conditions with no malfunction below the 2.2 and 2 cm(2) thresholds (1.19 cm(2) for severe PPM and 1.23 cm(2) for fully blocked leaflet). The mean pressure gradient reached 5 mm Hg thresholds for several conditions of severe PPM only (6.9 mm Hg and mean maximum velocity value: 183.4 cm/s) whereas such value was never attained in the case of leaflet obstruction. In the case of leaflet obstruction, the maximum velocity averaged over the nine pulsed-wave Doppler locations increased by 38% for partial leaflet obstruction and 75% for a fully blocked leaflet when compared with normal conditions. Current echocardiographic criteria might be suboptimal for the detection of bileaflet mechanical heart valve malfunction. Further developments and investigations are required in order

  4. 26. "AIR INSTALLATIONS; EDWARDS AIR FORCE BASE, CALIFORNIA; HIGH SPEED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. "AIR INSTALLATIONS; EDWARDS AIR FORCE BASE, CALIFORNIA; HIGH SPEED TEST TRACK." Drawing No. 10-259. One inch to 400 feet plan of original 10,000-foot sled track. No date. No D.O. series number. No headings as above. - Edwards Air Force Base, South Base Sled Track, Edwards Air Force Base, North of Avenue B, between 100th & 140th Streets East, Lancaster, Los Angeles County, CA

  5. Modelling the atmosphere of the carbon-rich Mira RU Virginis

    NASA Astrophysics Data System (ADS)

    Rau, G.; Paladini, C.; Hron, J.; Aringer, B.; Groenewegen, M. A. T.; Nowotny, W.

    2015-11-01

    Context. We study the atmosphere of the carbon-rich Mira RU Vir using the mid-infrared high spatial resolution interferometric observations from VLTI/MIDI. Aims: The aim of this work is to analyse the atmosphere of the carbon-rich Mira RU Vir with hydrostatic and dynamic models, in this way deepening the knowledge of the dynamic processes at work in carbon-rich Miras. Methods: We compare spectro-photometric and interferometric measurements of this carbon-rich Mira AGB star with the predictions of different kinds of modelling approaches (hydrostatic model atmospheres plus MOD-More Of Dusty, self-consistent dynamic model atmospheres). A geometric model fitting tool is used for a first interpretation of the interferometric data. Results: The results show that a joint use of different kinds of observations (photometry, spectroscopy, interferometry) is essential for shedding light on the structure of the atmosphere of a carbon-rich Mira. The dynamic model atmospheres fit the ISO spectrum well in the wavelength range λ = [2.9,25.0] μm. Nevertheless, a discrepancy is noticeable both in the SED (visible) and in the interferometric visibilities (shape and level), which is a possible explanation are intra-/inter-cycle variations in the dynamic model atmospheres, as well as in the observations. The presence of a companion star and/or a disk or a decrease in mass loss within the past few hundred years cannot be excluded, but these explanations are considered unlikely. Based on observations made with ESO telescopes at La Silla Paranal Observatory under programme IDs: 085.D-0756 and 093. D-0708.Appendix A is available in electronic form at http://www.aanda.org

  6. The symbiotic binary system RX Puppis: a possible recurrent nova with a Mira companion

    NASA Astrophysics Data System (ADS)

    Mikolajewska, Joanna; Brandi, Estela; Hack, Warren; Whitelock, Patricia A.; Barba, Rodolfo; Garcia, Lia; Marang, Freddy

    1999-05-01

    We present an analysis of photometric and spectroscopic observations of the symbiotic binary system RX Pup with the aim of developing a reliable binary model for the system and identifying mechanisms responsible for its spectacular activity. The binary is composed of a long-period Mira variable surrounded by a thick dust shell and a hot ~ 0.8 M_sun white dwarf companion. The hot component produces practically all activity observed in the UV, optical and radio range, while variable obscuration of the Mira by circumstellar dust is responsible for long-term changes in the near-infrared magnitudes. The observations show that RX Pup underwent a nova-like eruption during the last three decades. The hot component contracted in radius at roughly constant luminosity from 1975 to 1986, and was the source of a strong stellar wind, which prevented it from accreting material lost in the Mira wind. Around 1988/9 the hot component turned over in the Hertzsprung-Russell (HR) diagram and by 1991 its luminosity had faded by a factor of ~ 30 with respect to the maximum plateau value and the hot wind had practically ceased. By 1995 the nova remnant started to accrete material from the Mira wind, as indicated by a general increase in intensity of the optical continuum and H I emission. The quiescent spectrum resembles the quiescent spectra of symbiotic recurrent novae, and its intensity indicates that the hot component must accrete as much as ~ 1 per cent of the Mira wind, which is more or less the amount predicted by Bondi-Hoyle theory. The earliest observational records from the 1890s suggest that another nova-like eruption of RX Pup occurred around 1894.

  7. 1995 Edward teller lecture. Patience and optimism

    SciTech Connect

    Miley, G.H.

    1996-05-01

    Remarks made in the author{close_quote}s acceptance lecture for the 1995 Edward Teller Medal are presented and expanded. Topics covered include research on nuclear-pumped lasers, the first direct e-beam-pumped laser, direct energy conversion and advanced fuel fusion, plus recent work on inertial electrostatic confinement. {open_quote}{open_quote}Patience{close_quote}{close_quote} and {open_quote}{open_quote}optimism{close_quote}{close_quote} are viewed as essential elements needed by scientists following the {open_quote}{open_quote}zig-zag{close_quote}{close_quote} path to fusion energy production. {copyright} {ital 1996 American Institute of Physics.}

  8. Edward Jenner and the eradication of smallpox.

    PubMed

    Willis, N J

    1997-08-01

    Edward Jenner's careful investigations into the usefulness of cowpox vaccination for the prevention of smallpox during the late 1790s, and his enthusiastic and continued advocation of vaccination despite the scepticism of critics, laid the foundations for the growth of understanding about the nature of infectious disease and the development of immunity during the 19th century. He began the long process which resulted in the successful eradication of the smallpox virus in 1980. His life story remains an inspiration to physicians facing an uncertain future as viruses and bacteria not yet eradicated adapt to the antibiotic age.

  9. Ethical reflections on Edward Jenner's experimental treatment.

    PubMed

    Davies, Hugh

    2007-03-01

    In 1798 Dr Edward Jenner published his famous account of "vaccination". Some claim that a Research Ethics Committee, had it existed in the 1790s, might have rejected his work. I provide the historical context of his work and argue that it addressed a major risk to the health of the community, and, given the devastating nature of smallpox and the significant risk of variolation, the only alternative preventative measure, Jenner's study had purpose, justification and a base in the practice of the day.

  10. Edward Jenner's Inquiry; a bicentenary analysis.

    PubMed

    Baxby, D

    1999-01-28

    Edward Jenner's famous Inquiry was published 200 years ago. Probably few now know on what evidence he based his claims but most will be aware that they initiated controversy which to some extent still continues. This paper briefly reviews the Inquiry, analysing its merits and faults. Jenner's claims were based on slender experimental evidence and some of the information presented was incomplete and misleading. However Jenner's role in the introduction of vaccination was seminal and others could only test and extend his ideas. His reputation as the initial promoter of vaccination is justified.

  11. Orbiter 101 'Enterprise' lands at Edwards AFB

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The rear wheels of the Space Shuttle Orbiter 101 raise desert sand on the landing strip at Edwards Air Force Base as the 'Enterprise' completes the fourth of five scheduled Approach and Landing Test (ALT) free flights. This mission marked the first occasion of the orbiter to fly minus tail cone. The unpowered phase, with Astronauts Joe H. Engle, commander, and Richard H. Truly, pilot, controlling the Enterprise, took two-minutes and 34 seconds. One of the T-38 chase planes that remained with the Shuttle craft for the mission's duration is partially visible at right.

  12. Ethical reflections on Edward Jenner's experimental treatment.

    PubMed

    Davies, Hugh

    2007-03-01

    In 1798 Dr Edward Jenner published his famous account of "vaccination". Some claim that a Research Ethics Committee, had it existed in the 1790s, might have rejected his work. I provide the historical context of his work and argue that it addressed a major risk to the health of the community, and, given the devastating nature of smallpox and the significant risk of variolation, the only alternative preventative measure, Jenner's study had purpose, justification and a base in the practice of the day. PMID:17329392

  13. Edwards plateau: Analysis of land cover trends

    USGS Publications Warehouse

    Friesen, B.A.; Hester, D.J.; Casey, K.A.

    2004-01-01

    The Land Cover Trends project studies the rates, causes, and consequences of contemporary (1973-2000) change in land use and land cover in the United States on an ecoregional basis. The Edwards Plateau ecoregion is the focus of this report. Landsat imagery from five dates during a nearly 30-year period are interpreted for randomly selected sample blocks. The resulting data provide the foundation for estimating change. Along with the image analysis, site visits to 90% of the sampled areas, geographical profiles, and socioeconomic data for the ecoregion are synthesized to assess regional driving forces and consequences of change. Complete project methodology can be found in Loveland et al [1].

  14. Ethical reflections on Edward Jenner's experimental treatment

    PubMed Central

    Davies, Hugh

    2007-01-01

    In 1798 Dr Edward Jenner published his famous account of “vaccination”. Some claim that a Research Ethics Committee, had it existed in the 1790s, might have rejected his work. I provide the historical context of his work and argue that it addressed a major risk to the health of the community, and, given the devastating nature of smallpox and the significant risk of variolation, the only alternative preventative measure, Jenner's study had purpose, justification and a base in the practice of the day. PMID:17329392

  15. Blood damage through a bileaflet mechanical heart valve: a quantitative computational study using a multiscale suspension flow solver.

    PubMed

    Min Yun, B; Aidun, Cyrus K; Yoganathan, Ajit P

    2014-10-01

    Bileaflet mechanical heart valves (BMHVs) are among the most popular prostheses to replace defective native valves. However, complex flow phenomena caused by the prosthesis are thought to induce serious thromboembolic complications. This study aims at employing a novel multiscale numerical method that models realistic sized suspended platelets for assessing blood damage potential in flow through BMHVs. A previously validated lattice-Boltzmann method (LBM) is used to simulate pulsatile flow through a 23 mm St. Jude Medical (SJM) Regent™ valve in the aortic position at very high spatiotemporal resolution with the presence of thousands of suspended platelets. Platelet damage is modeled for both the systolic and diastolic phases of the cardiac cycle. No platelets exceed activation thresholds for any of the simulations. Platelet damage is determined to be particularly high for suspended elements trapped in recirculation zones, which suggests a shift of focus in blood damage studies away from instantaneous flow fields and toward high flow mixing regions. In the diastolic phase, leakage flow through the b-datum gap is shown to cause highest damage to platelets. This multiscale numerical method may be used as a generic solver for evaluating blood damage in other cardiovascular flows and devices. PMID:25070372

  16. Device Thrombogenicty Emulator (DTE) – Design optimization Methodology for Cardiovascular Devices: A Study in Two Bileaflet MHV Designs

    PubMed Central

    Xenos, Michalis; Girdhar, Gaurav; Alemu, Yared; Jesty, Jolyon; Slepian, Marvin; Einav, Shmuel; Bluestein, Danny

    2010-01-01

    Patients who receive prosthetic heart valve (PHV) implants require mandatory anticoagulation medication after implantation due to the thrombogenic potential of the valve. Optimization of PHV designs may facilitate reduction of flow-induced thrombogenicity and reduce or eliminate the need for post-implant anticoagulants. We present a methodology entitled Device Thrombogenicty Emulator (DTE) for optimizing the thrombo-resistance performance of PHV by combining numerical and experimental approaches. Two bileaflet mechanical heart valves (MHV) designs – St. Jude Medical (SJM) and ATS were investigated, by studying the effect of distinct flow phases on platelet activation. Transient turbulent and direct numerical simulations (DNS) were conducted, and stress loading histories experienced by the platelets were calculated along flow trajectories. The numerical simulations indicated distinct design dependent differences between the two valves. The stress-loading waveforms extracted from the numerical simulations were programmed into a hemodynamic shearing device (HSD), emulating the flow conditions past the valves in distinct ‘hot spot’ flow regions that are implicated in MHV thrombogenicity. The resultant platelet activity was measured with a modified prothrombinase assay, and was found to be significantly higher in the SJM valve, mostly during the regurgitation phase. The experimental results were in excellent agreement with the calculated platelet activation potential. This establishes the utility of the DTE methodology for serving as a test bed for evaluating design modifications for achieving better thrombogenic performance for such devices. PMID:20483411

  17. The effect of implantation orientation of a bileaflet mechanical heart valve on kinematics and hemodynamics in an anatomic aorta.

    PubMed

    Borazjani, Iman; Sotiropoulos, Fotis

    2010-11-01

    We carry out three-dimensional high-resolution numerical simulations of a bileaflet mechanical heart valve under physiologic pulsatile flow conditions implanted at different orientations in an anatomic aorta obtained from magnetic resonance imaging (MRI) of a volunteer. We use the extensively validated for heart valve flow curvilinear-immersed boundary (CURVIB) fluid-structure interaction (FSI) solver in which the empty aorta is discretized with a curvilinear, aorta-conforming grid while the valve is handled as an immersed boundary. The motion of the valve leaflets are calculated through a strongly coupled FSI algorithm implemented in conjunction with the Aitken convergence acceleration technique. We perform simulations for three valve orientations, which differ from each other by 45 deg and compare the results in terms of leaflet motion and flow field. We show that the valve implanted symmetrically relative to the symmetry plane of the ascending aorta curvature exhibits the smallest overall asymmetry in the motion of its two leaflets and lowest rebound during closure. Consequently, we hypothesize that this orientation is beneficial to reduce the chance of intermittent regurgitation. Furthermore, we find that the valve orientation does not significantly affect the shear stress distribution in the aortic lumen, which is in agreement with previous studies. PMID:21034146

  18. Edward F. Diener: Award for Distinguished Scientific Contributions

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents Edward F. Diener as one of the winners of the American Psychological Association's Award for Distinguished Scientific Contributions (2012). Edward F. Diener has been a leader in every aspect of well-being research. He provided an influential conception of well-being as consisting of cognitive and emotional elements. A citation, biography,…

  19. 76 FR 76710 - Baine, Edward H.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Baine, Edward H.; Notice of Filing Take notice that on December 1, 2011, Edward H. Baine submitted for filing, an application for authority to hold interlocking...

  20. Effect of heart rate on the hemodynamics of bileaflet mechanical heart valves' prostheses (St. Jude Medical) in the aortic position and in the opening phase: A computational study.

    PubMed

    Jahandardoost, Mehdi; Fradet, Guy; Mohammadi, Hadi

    2016-03-01

    To date, to the best of the authors' knowledge, in almost all of the studies performed around the hemodynamics of bileaflet mechanical heart valves, a heart rate of 70-72 beats/min has been considered. In fact, the heart rate of ~72 beats/min does not represent the entire normal physiological conditions under which the aortic or prosthetic valves function. The heart rates of 120 or 50 beats/min may lead to hemodynamic complications, such as plaque formation and/or thromboembolism in patients. In this study, the hemodynamic performance of the bileaflet mechanical heart valves in a wide range of normal and physiological heart rates, that is, 60-150 beats/min, was studied in the opening phase. The model considered in this study was a St. Jude Medical bileaflet mechanical heart valve with the inner diameter of 27 mm in the aortic position. The hemodynamics of the native valve and the St. Jude Medical valve were studied in a variety of heart rates in the opening phase and the results were carefully compared. The results indicate that peak values of the velocity profile downstream of the valve increase as heart rate increases, as well as the location of the maximum velocity changes with heart rate in the St. Jude Medical valve model. Also, the maximum values of shear stress and wall shear stresses downstream of the valve are proportional to heart rate in both models. Interestingly, the maximum shear stress and wall shear stress values in both models are in the same range when heart rate is <90 beats/min; however, these values significantly increase in the St. Jude Medical valve model when heart rate is >90 beats/min (up to ~40% growth compared to that of the native valve). The findings of this study may be of importance in the hemodynamic performance of bileaflet mechanical heart valves. They may also play an important role in design improvement of conventional prosthetic heart valves and the design of the next generation of prosthetic valves, such as

  1. Effect of heart rate on the hemodynamics of bileaflet mechanical heart valves' prostheses (St. Jude Medical) in the aortic position and in the opening phase: A computational study.

    PubMed

    Jahandardoost, Mehdi; Fradet, Guy; Mohammadi, Hadi

    2016-03-01

    To date, to the best of the authors' knowledge, in almost all of the studies performed around the hemodynamics of bileaflet mechanical heart valves, a heart rate of 70-72 beats/min has been considered. In fact, the heart rate of ~72 beats/min does not represent the entire normal physiological conditions under which the aortic or prosthetic valves function. The heart rates of 120 or 50 beats/min may lead to hemodynamic complications, such as plaque formation and/or thromboembolism in patients. In this study, the hemodynamic performance of the bileaflet mechanical heart valves in a wide range of normal and physiological heart rates, that is, 60-150 beats/min, was studied in the opening phase. The model considered in this study was a St. Jude Medical bileaflet mechanical heart valve with the inner diameter of 27 mm in the aortic position. The hemodynamics of the native valve and the St. Jude Medical valve were studied in a variety of heart rates in the opening phase and the results were carefully compared. The results indicate that peak values of the velocity profile downstream of the valve increase as heart rate increases, as well as the location of the maximum velocity changes with heart rate in the St. Jude Medical valve model. Also, the maximum values of shear stress and wall shear stresses downstream of the valve are proportional to heart rate in both models. Interestingly, the maximum shear stress and wall shear stress values in both models are in the same range when heart rate is <90 beats/min; however, these values significantly increase in the St. Jude Medical valve model when heart rate is >90 beats/min (up to ~40% growth compared to that of the native valve). The findings of this study may be of importance in the hemodynamic performance of bileaflet mechanical heart valves. They may also play an important role in design improvement of conventional prosthetic heart valves and the design of the next generation of prosthetic valves, such as

  2. The kinematics of Mira variables in the windows towards the Galactic Centre

    NASA Astrophysics Data System (ADS)

    Feast, M. W.; Robertson, B. S. C.; Black, C.

    1980-01-01

    Radial velocities are given for 23 Mira variables in the Galactic Center window fields of Baade (Sgr I and the NGC 6522 field). The data are combined with velocities determined from other objects to obtain the velocity of the local standard of rest with respect to objects near the center. This velocity is not found to differ significantly from zero and thus there is no evidence for a high outward velocity of the local standard of rest. The velocity dispersion of the Miras is 112 km/s. OH/IR sources near the center have a similar dispersion (Baud) although the space distribution around the center of these two classes of objects seems different.

  3. Resolving the extended atmosphere and the inner wind of Mira (o Ceti) with long ALMA baselines

    NASA Astrophysics Data System (ADS)

    Wong, K. T.; Kamiński, T.; Menten, K. M.; Wyrowski, F.

    2016-05-01

    Context. High angular resolution (sub)millimetre observations of asymptotic giant branch (AGB) stars, now possible with the Atacama Large Millimeter/submillimeter Array (ALMA), allow direct imaging of these objects' photospheres. The physical properties of the molecular material around these regions, which until now has only been studied by imaging of maser emission and spatially unresolved absorption spectroscopy, can be probed with radiative transfer modelling and compared to hydrodynamical model predictions. The prototypical Mira variable, o Cet (Mira), was observed as a Science Verification target in the 2014 ALMA Long Baseline Campaign, offering the first opportunity to study these physical conditions in detail. Aims: With the longest baseline of 15 km, ALMA produces clearly resolved images of the continuum and molecular line emission/absorption at an angular resolution of ~30 mas at 220 GHz. Models are constructed for Mira's extended atmosphere to investigate the physics and molecular abundances therein. Methods: We imaged the data of 28SiO ν= 0, 2J = 5-4 and H2O v2 = 1JKa,Kc = 55,0-64,3 transitions and extracted spectra from various lines of sight towards Mira's extended atmosphere. In the course of imaging the emission/absorption, we encountered ambiguities in the resulting images and spectra that appear to be related to the performance of the CLEAN algorithm when applied to a combination of extended emission, and compact emission and absorption. We addressed these issues by a series of tests and simulations. We derived the gas density, kinetic temperature, molecular abundance, and outflow/infall velocities in Mira's extended atmosphere by modelling the SiO and H2O lines. Results: We resolve Mira's millimetre continuum emission and our data are consistent with a radio photosphere with a brightness temperature of 2611 ± 51 K. In agreement with recent results obtained with the Very Large Array, we do not confirm the existence of a compact region (<5 mas) of

  4. "Ask a slave" and interpreting race on public history's front line: interview with Azie Mira Dungey.

    PubMed

    Dungey, Azie Mira; Tyson, Amy M

    2014-02-01

    In this interview, Azie Mira Dungey (creator of the web series, "Ask a Slave") and Amy M. Tyson (Associate Professor of History at DePaul University and author of The Wages of History: Emotional Labor on Public History's Front Lines) discuss Dungey's web series, as well as her experiences as a living history interpreter at both the Smithsonian Museum of American History and at Mount Vernon.

  5. "Ask a slave" and interpreting race on public history's front line: interview with Azie Mira Dungey.

    PubMed

    Dungey, Azie Mira; Tyson, Amy M

    2014-02-01

    In this interview, Azie Mira Dungey (creator of the web series, "Ask a Slave") and Amy M. Tyson (Associate Professor of History at DePaul University and author of The Wages of History: Emotional Labor on Public History's Front Lines) discuss Dungey's web series, as well as her experiences as a living history interpreter at both the Smithsonian Museum of American History and at Mount Vernon. PMID:24988786

  6. Edward jenner and the small pox vaccine.

    PubMed

    Smith, Kendall A

    2011-01-01

    Edward Jenner, who discovered that it is possible to vaccinate against Small Pox using material from Cow Pox, is rightly the man who started the science of immunology. However, over the passage of time many of the details surrounding his astounding discovery have been lost or forgotten. Also, the environment within which Jenner worked as a physician in the countryside, and the state of the art of medicine and society are difficult to appreciate today. It is important to recall that people were still being bled at the time, to relieve the presence of evil humors. Accordingly, this review details Jenner's discovery and attempts to place it in historical context. Also, the vaccine that Jenner used, which decreased the prevalence of Small Pox worldwide in his own time, and later was used to eradicate Small Pox altogether, is discussed in light of recent data.

  7. Edward jenner and the small pox vaccine.

    PubMed

    Smith, Kendall A

    2011-01-01

    Edward Jenner, who discovered that it is possible to vaccinate against Small Pox using material from Cow Pox, is rightly the man who started the science of immunology. However, over the passage of time many of the details surrounding his astounding discovery have been lost or forgotten. Also, the environment within which Jenner worked as a physician in the countryside, and the state of the art of medicine and society are difficult to appreciate today. It is important to recall that people were still being bled at the time, to relieve the presence of evil humors. Accordingly, this review details Jenner's discovery and attempts to place it in historical context. Also, the vaccine that Jenner used, which decreased the prevalence of Small Pox worldwide in his own time, and later was used to eradicate Small Pox altogether, is discussed in light of recent data. PMID:22566811

  8. Resolving asymmetries along the pulsation cycle of the Mira star X Hydrae

    NASA Astrophysics Data System (ADS)

    Haubois, X.; Wittkowski, M.; Perrin, G.; Kervella, P.; Mérand, A.; Thiébaut, E.; Ridgway, S. T.; Ireland, M.; Scholz, M.

    2015-10-01

    Context. The mass-loss process in Mira stars probably occurs in an asymmetric way where dust can form in inhomogeneous circumstellar molecular clumps. Following asymmetries along the pulsation cycle can give us clues about these mass-loss processes. Aims: We imaged the Mira star X Hya and its environnement at different epochs to follow the evolution of the morphology in the continuum and in the molecular bands. Methods: We observed X Hya with AMBER in J-H-K at low resolution at two epochs. We modelled squared visibilities with geometrical and physical models. We also present imaging reconstruction results obtained with MiRA and based on the physical a priori images. Results: We report on the angular scale change of X Hya between the two epochs. 1D CODEX profiles allowed us to understand and model the spectral variation of squared visibilities and constrain the stellar parameters. Reconstructed model-dependent images enabled us to reproduce closure phase signals and the azimuthal dependence of squared visibilities. They show evidence for material inhomogeneities located in the immediate environment of the star. Based on observations obtained with the ESO VLTI/ATs telescopes under the program ID 084.D-0326. Figures 7-12 are available in electronic form at http://www.aanda.org

  9. Comparison of hinge microflow fields of bileaflet mechanical heart valves implanted in different sinus shape and downstream geometry.

    PubMed

    Kuan, Yee Han; Kabinejadian, Foad; Nguyen, Vinh-Tan; Su, Boyang; Yoganathan, Ajit P; Leo, Hwa Liang

    2015-01-01

    The characterization of the bileaflet mechanical heart valves (BMHVs) hinge microflow fields is a crucial step in heart valve engineering. Earlier in vitro studies of BMHV hinge flow at the aorta position in idealized straight pipes have shown that the aortic sinus shapes and sizes may have a direct impact on hinge microflow fields. In this paper, we used a numerical study to look at how different aortic sinus shapes, the downstream aortic arch geometry, and the location of the hinge recess can influence the flow fields in the hinge regions. Two geometric models for sinus were investigated: a simplified axisymmetric sinus and an idealized three-sinus aortic root model, with two different downstream geometries: a straight pipe and a simplified curved aortic arch. The flow fields of a 29-mm St Jude Medical BMHV with its four hinges were investigated. The simulations were performed throughout the entire cardiac cycle. At peak systole, recirculating flows were observed in curved downsteam aortic arch unlike in straight downstream pipe. Highly complex three-dimensional leakage flow through the hinge gap was observed in the simulation results during early diastole with the highest velocity at 4.7 m/s, whose intensity decreased toward late diastole. Also, elevated wall shear stresses were observed in the ventricular regions of the hinge recess with the highest recorded at 1.65 kPa. Different flow patterns were observed between the hinge regions in straight pipe and curved aortic arch models. We compared the four hinge regions at peak systole in an aortic arch downstream model and found that each individual hinge did not vary much in terms of the leakage flow rate through the valves. PMID:25343223

  10. Computational simulations of flow dynamics and blood damage through a bileaflet mechanical heart valve scaled to pediatric size and flow.

    PubMed

    Yun, B Min; McElhinney, Doff B; Arjunon, Shiva; Mirabella, Lucia; Aidun, Cyrus K; Yoganathan, Ajit P

    2014-09-22

    Despite pressing needs, there are currently no FDA approved prosthetic valves available for use in the pediatric population. This study is performed for predictive assessment of blood damage in bileaflet mechanical heart valves (BMHVs) with pediatric sizing and flow conditions. A model of an adult-sized 23 mm St. Jude Medical (SJM) Regent(™) valve is selected for use in simulations, which is scaled in size for a 5-year old child and 6-month old infant. A previously validated lattice-Boltzmann method (LBM) is used to simulate pulsatile flow with thousands of suspended platelets for cases of adult, child, and infant BMHV flows. Adult BMHV flows demonstrate more disorganized small-scale flow features, but pediatric flows are associated with higher fluid shear stresses. Platelet damage in the pediatric cases is higher than in adult flow, highlighting thrombus complication dangers of pediatric BMHV flows. This does not necessarily suggest clinically important differences in thromboembolic potential. Highly damaged platelets in pediatric flows are primarily found far downstream of the valve, as there is less flow recirculation in pediatric flows. In addition, damage levels are well below expected thresholds for platelet activation. The extent of differences here documented between the pediatric and adult cases is of concern, demanding particular attention when pediatric valves are designed and manufactured. However, the differences between the pediatric and adult cases are not such that development of pediatric sized valves is untenable. This study may push for eventual approval of prosthetic valves resized for the pediatric population. Further studies will be necessary to determine the validity and potential thrombotic and clinical implications of these findings. PMID:25011622

  11. R Centauri: An Unusual Mira Variable in a He-shell Flash

    NASA Astrophysics Data System (ADS)

    Hawkins, George; Mattei, Janet A.; Foster, Grant

    R Cen is an oxygen-rich Mira variable with a period of 546 days, amplitude of 5.3-11.8 V, and spectral type of M4e-M8IIe, as listed in the General Catalogue of Variable Stars (Kholopov et al. 1985). It is one of only a few Miras with double-peaked maxima in its light curve (e.g., Keenan et al. 1974). Our power spectrum shows harmonics up to 8 times the main mode at 546 days. The most likely explanation for the double-peaked light curve is a resonance between the fundamental and an overtone mode, with f?=2f? similar to that observed in bump Cepheids (Buchler et al. 1990), or a half integer resonance as suspected in Cepheids with period doubling (Kovacs and Buchler 1988). Visual observations from 1918 to 2000 from the AAVSO International Database show two unusual properties: 1) the pulsation amplitude has decreased by 3 magnitudes since 1950 (Figure 1), and 2) the period of the dominant mode has been steadily decreasing from 550 days at JD 2434000 (1951) to its present value of 505-510 days (Figure 2). Figure 2 shows the results of a statistical analysis using the weighted wavelet Z-transform (Foster 1996) and a Cleanest Fourier analysis (Foster 1995). We suggest that the recent behavior is due to R Cen entering a He-shell flash in its interior, as the period decrease of 1 day/yr is similar to that of other Miras thought to be undergoing a He-shell flash, such as R Hya and R Aql (Wood and Zarro 1981), and T Umi (Mattei and Foster 1995; Gal and Szatmary 1995). A star in a He-shell change may show a period change lasting only a few tens of years if it is caught right after the flash begins, or the change could last a few hundred to a few thousand years if it appears after the luminosity of the He-shell flash reaches the surface (Wood and Zarro 1981). However, R Cen should be monitored closely in the future, as some Mira variables (such as S Her and T Cep, se Wood and Zarro 1981) show short term period changes that are unrelated to a He-shell flash. We give further

  12. 7. MOTION PICTURE CAMERA STAND AT BUILDING 8768. Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. MOTION PICTURE CAMERA STAND AT BUILDING 8768. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Observation Bunkers for Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  13. 8. SOUTH REAR, SUPERSTRUCTURE. Looking north from deck. Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. SOUTH REAR, SUPERSTRUCTURE. Looking north from deck. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  14. 8. BUILDING 8769, WEST FRONT AND SOUTH SIDE. Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. BUILDING 8769, WEST FRONT AND SOUTH SIDE. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Observation Bunkers for Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  15. 5. EAST SIDE, TEST STAND AND ITS SUPERSTRUCTURE. Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. EAST SIDE, TEST STAND AND ITS SUPERSTRUCTURE. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  16. 2. BUILDING 8767, SOUTH FRONT AND EAST SIDE. Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. BUILDING 8767, SOUTH FRONT AND EAST SIDE. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Observation Bunkers for Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  17. DETAIL, CONTROL BOOTH, RP1 TANK FARM Edwards Air Force ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL, CONTROL BOOTH, RP1 TANK FARM - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Combined Fuel Storage Tank Farm, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  18. 4. BUILDING 8767, INTERIOR. Looking west. Edwards Air Force ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. BUILDING 8767, INTERIOR. Looking west. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Observation Bunkers for Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  19. 6. BUILDING 8768, NORTHWEST SIDE AND SOUTHWEST FRONT. Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. BUILDING 8768, NORTHWEST SIDE AND SOUTHWEST FRONT. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Observation Bunkers for Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  20. 4. DETAIL SHOWING FLAME DEFLECTOR. Looking southeast. Edwards Air ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. DETAIL SHOWING FLAME DEFLECTOR. Looking southeast. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-A, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

  1. 5Q4: Chris Edwards - Child Presence Sensor

    NASA Video Gallery

    Five Questions For (5Q4) Chris Edwards, NASA engineer who was the team lead of a group that invented a child presence sensor designed to alert parents if they've inadvertently left their child in h...

  2. 14. Photocopy of Illustration from Buffet, Edward P., 'Some Long ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of Illustration from Buffet, Edward P., 'Some Long Island Windmills,' American Machinist, 17 October 1918, p. 728 STONE CRANE AT THE SHELTER ISLAND WINDMILL - Shelter Island Windmill, Manwaring Road, Shelter Island, Suffolk County, NY

  3. Edward Teller Medal: Laudations and Citations 2005-2015

    NASA Astrophysics Data System (ADS)

    Hora, Heinrich; Miley, George H.

    2016-10-01

    The following sections are included: * Max Tabak * Joseph D. Kilkenny * Kunioki Mima * Brian R. Thomas * Ricardo Betti * Edward I. Moses * Christine Garban-Labaune * Bruce A. Remington * James Hammer * Richard Petrasso * Jie Zhang * Hiroshi Azechi

  4. CONTROL BUILDING, WEST FRONT SHOWING ENTRANCE Edwards Air Force ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CONTROL BUILDING, WEST FRONT SHOWING ENTRANCE - Edwards Air Force Base, X-15 Engine Test Complex, Firing Control Building, Rogers Dry Lake, east of runway between North Base & South Base, Boron, Kern County, CA

  5. 6. OUTER BLAST DOOR, WEST REAR. Edwards Air Force ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. OUTER BLAST DOOR, WEST REAR. - Edwards Air Force Base, South Base Sled Track, Firing & Control Blockhouse for 10,000-foot Track, South of Sled Track at midpoint of 20,000-foot track, Lancaster, Los Angeles County, CA

  6. 5. NORTH SIDE AND WEST REAR. Edwards Air Force ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. NORTH SIDE AND WEST REAR. - Edwards Air Force Base, South Base Sled Track, Firing & Control Blockhouse for 10,000-foot Track, South of Sled Track at midpoint of 20,000-foot track, Lancaster, Los Angeles County, CA

  7. 3. SOUTH SIDE. Edwards Air Force Base, South Base ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. SOUTH SIDE. - Edwards Air Force Base, South Base Sled Track, Firing & Control Blockhouse for 10,000-foot Track, South of Sled Track at midpoint of 20,000-foot track, Lancaster, Los Angeles County, CA

  8. 3. Photocopy of lithograph by Edward A. Wilson, owned by ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopy of lithograph by Edward A. Wilson, owned by Mrs. Arthur Williams, owner of the house in 1960. JOSHUA DYER HOUSE FROM THE REAR - Joshua Dyer House, North Pamet Road, Truro, Barnstable County, MA

  9. Edward Mills Purcell, August 30, 1912-March 7, 1997

    NASA Astrophysics Data System (ADS)

    Rigden, John S.

    2011-03-01

    I discuss the life, education, personality, and contributions of Edward Mills Purcell (1912-1997) to physics, radio astronomy, astrophysics, biological physics, physics teaching and education, and to the nation.

  10. Edward Teller Medal: Acceptance Remarks (lirpp Vol. 10)

    NASA Astrophysics Data System (ADS)

    Nuckolls, John H.

    2016-10-01

    I am honored to receive this award. It is especially significant because Edward Teller is the father of inertial fusion. Teller's pioneering work in the extreme compressibility of matter, the radiation implosion concept, and the physics of thermonuclear burn are fundamental to the creation of very small scale inertially confined fusion explosions. Edward also made key contributions by fighting to reduce secrecy and by promoting international collaborations...

  11. The ironic detachment of Edward Gibbon.

    PubMed

    Trosman, Harry

    2009-06-01

    Edward Gibbon, the author of The History of the Decline and Fall of the Roman Empire, has been widely recognized as a master of irony. The historian's early life with parents he found self-serving and unreliable, his reaction to the events surrounding the death of his mother at the age of 9 and the decline of his father, left an impact on his personality and played a role in determining his choice of his life work. Irony has been approached from a psychoanalytic perspective as a mode of communication, as a stylistic device, as a modality through which one might view reality and as a way of uncovering the linkage between pretense and aspiration, between the apparent and the real. Gibbon's ironic detachment can be understood as rooted in his life history. He felt detached from his family of origin, in need of a protective device which would enable him to deal with passion. Sexual and aggressive impulses mobilized defensive postures that were later transformed into an attitude of skepticism and an interest in undercutting false beliefs and irrational authority, positions he attributes to religious ideation which served to instigate historical decline.

  12. Episodic karstification, Edwards Plateau, central Texas

    SciTech Connect

    Kastning, E.H.

    1985-01-01

    The Edwards Plateau and Llano Basin of central Texas form one of the largest contiguous regions of karst in North America (>80,000 km/sup 2/). Solutional phenomena show that several major episodes of karstification are documentable from late Cambrian to Holocene. Relict landforms representing intervals of solutional activity correlate well with the accepted geomorphic chronology for central Texas. Secondary porosity are vertically controlled by lithology, topographic incision of streams, position of the potentiometric surface, and attitude of bedding. Areally, development of karst is strongly influenced by the extent, density, and orientation of fractures and by hydrodynamic characteristics such as points of recharge and discharge, degree of integration of groundwater flow paths, and hydraulic gradients. Early episodes of karstification correspond to intervals of subaerial exposure of carbonate rocks during marine regression or following regional uplift. Paleokarst is prevalent in the Paleozoic and Mesozoic sequences. Infilled dolines and solution-collapse breccias have been exhumed by extensive regional denudation during the Cenozoic Era. Subaerial conditions during the middle Cretaceous account for infilled solutional cavities within lower Cretaceous carbonate beds. The most extensive karstification began with regional uplift in the early Miocene. Enhanced relief along the Balcones escarpment promoted incision of streams, lowering of water tables, steepened hydraulic gradients, and increases in discharge. Caves at various-elevations attest to sequential dissection of the plateau during the late Quaternary.

  13. Craniofacial abnormalities among patients with Edwards Syndrome

    PubMed Central

    Rosa, Rafael Fabiano M.; Rosa, Rosana Cardoso M.; Lorenzen, Marina Boff; Zen, Paulo Ricardo G.; Graziadio, Carla; Paskulin, Giorgio Adriano

    2013-01-01

    OBJECTIVE To determine the frequency and types of craniofacial abnormalities observed in patients with trisomy 18 or Edwards syndrome (ES). METHODS This descriptive and retrospective study of a case series included all patients diagnosed with ES in a Clinical Genetics Service of a reference hospital in Southern Brazil from 1975 to 2008. The results of the karyotypic analysis, along with clinical data, were collected from medical records. RESULTS: The sample consisted of 50 patients, of which 66% were female. The median age at first evaluation was 14 days. Regarding the karyotypes, full trisomy of chromosome 18 was the main alteration (90%). Mosaicism was observed in 10%. The main craniofacial abnormalities were: microretrognathia (76%), abnormalities of the ear helix/dysplastic ears (70%), prominent occiput (52%), posteriorly rotated (46%) and low set ears (44%), and short palpebral fissures/blepharophimosis (46%). Other uncommon - but relevant - abnormalities included: microtia (18%), orofacial clefts (12%), preauricular tags (10%), facial palsy (4%), encephalocele (4%), absence of external auditory canal (2%) and asymmetric face (2%). One patient had an initial suspicion of oculo-auriculo-vertebral spectrum (OAVS) or Goldenhar syndrome. CONCLUSIONS: Despite the literature description of a characteristic clinical presentation for ES, craniofacial alterations may be variable among these patients. The OAVS findings in this sample are noteworthy. The association of ES with OAVS has been reported once in the literature. PMID:24142310

  14. Edward B. Aveling: the people's Darwin.

    PubMed

    Paylor, Suzanne

    2005-06-01

    By the late-19th century, evolutionary theory, known by most people as Darwinism, had earned a reputation as an atheistic theory that challenged religious orthodoxy. From recent historical work we now know a great deal about how those with religious convictions received Darwinian ideas, and the role that professional scientists played in styling and communicating 'Darwinism' to the wider public and between themselves. However, relatively little is known about how Darwinian ideas were received and used by avowedly irreligious groups, and how these groups set about communicating their own version of Darwinism to a public hungry for cheap and accessible science. The activities of the Secularist Edward Bibbins Aveling, a prolific popularizer of Darwinian ideas in the late-19th century, offer a unique insight into this relatively uncharted territory. His work helped to develop the polemic of popular irreligious groups and imbue Darwinism with overtly atheistic connotations; it also engendered unprecedented support for atheism from the general public, and challenged the monopoly that some professional scientists enjoyed over imparting serious scientific knowledge to them.

  15. Untersuchung der Mira-Sterne RT Boo, TV Peg und VX Aur

    NASA Astrophysics Data System (ADS)

    Raetz, Kerstin; Berthold, Thomas

    2015-02-01

    The light-change of the Mira stars RT Boo, TV Peg and VX Aur was analyzed on three ways for a long time. In the first period I estimated the brightness of the variables on sky monitoring photo plates (red spectral range) from Sonneberg Observatory with Argelander¥s Method, in the last years I measured scanned photo plates with a photometry program and in addition I used visual observations from A.A.V.S.O. for the analysis. The behavior of the periods of the tree stars from 1965 to 2013 is described here.

  16. Oxygen-rich Mira variables: Near-infrared luminosity calibrations. Populations and period-luminosity relations

    NASA Technical Reports Server (NTRS)

    Alvarez, R.; Mennessier, M.-O.; Barthes, D.; Luri, X.; Mattei, J. A.

    1997-01-01

    Hipparcos astrometric and kinematical data of oxygen-rich Mira variables are used to calibrate absolute near-infrared magnitudes and kinematic parameters. Three distinct classes of stars with different kinematics and scale heights were identified. The two most significant groups present characteristics close to those usually assigned to extended/thick disk-halo populations and old disk populations, respectively, and thus they may differ by their metallicity abundance. Two parallel period-luminosity relations are found, one for each population. The shift between these relations is interpreted as the consequence of the effects of metallicity abundance on the luminosity.

  17. Search for surface magnetic fields in Mira stars. First detection in χ Cygni

    NASA Astrophysics Data System (ADS)

    Lèbre, A.; Aurière, M.; Fabas, N.; Gillet, D.; Herpin, F.; Konstantinova-Antova, R.; Petit, P.

    2014-01-01

    Context. So far, surface magnetic fields have never been detected on Mira stars. Only recently have the spectropolarimetric capabilities of measuring it via the Zeeman effect become available to us. Then, to complete the knowledge of the magnetic field and of its influence during the transition from asymptotic giant branch to planetary nebulae stages, we have undertaken a search for magnetic fields on the surface of Mira stars. Aims: Our main goal is to constrain - at this stage of stellar evolution - the surface magnetic field (presence and strength) and to define the magnetic field strength dependence along the radial distance to the star, above the photosphere and across the circumstellar envelope of cool and evolved stars. Methods: We used spectropolarimetric observations (Stokes V spectra probing circular polarization), collected with the Narval instrument at TBL, in order to detect - with the least squares deconvolution (LSD) method - a Zeeman signature in the visible part of the spectrum. Results: We present the first spectropolarimetric observations of the S-type Mira star χ Cyg, performed around its maximum light. We detected a polarimetric signal in the Stokes V spectra and established its Zeeman origin. We claim that it is likely to be related to a weak magnetic field present at the photospheric level and in the lower part of the stellar atmosphere. We estimated the strength of its longitudinal component to about 2-3 gauss. This result favors a 1/r law for the variation in the magnetic field strength across the circumstellar envelope of χ Cyg. This is the first detection of a weak magnetic field on the stellar surface of a Mira star, and we discuss its origin in the framework of shock waves periodically propagating throughout the atmosphere of these radially pulsating stars. Conclusions: At the date of our observations of χ Cyg, the shock wave reaches its maximum intensity, and it is likely that the shock amplifies a weak stellar magnetic field during

  18. X-31 in Flight over Edwards AFB

    NASA Technical Reports Server (NTRS)

    1994-01-01

    One of two X-31 Enhanced Fighter Maneuverability Demonstrator aircraft, flown by an international test organization at NASA's Dryden Flight Research Center, Edwards, California, turns tightly over the desert floor on a research flight. The aircraft obtained data that may apply to the design and development of highly-maneuverable aircraft of the future. The X-31 had a three-axis thrust-vectoring system, coupled with advanced flight controls, to allow it to maneuver tightly at very high angles of attack. The X-31 Enhanced Fighter Maneuverability (EFM) demonstrator flew at the Ames- Dryden Flight Research Facility, Edwards, California (redesignated the Dryden Flight Research Center in 1994) from February 1992 until 1995 and before that at the Air Force's Plant 42 in Palmdale, California. The goal of the project was to provide design information for the next generation of highly maneuverable fighter aircraft. This program demonstrated the value of using thrust vectoring (directing engine exhaust flow) coupled with an advanced flight control system to provide controlled flight to very high angles of attack. The result was a significant advantage over most conventional fighters in close-in combat situations. The X-31 flight program focused on agile flight within the post-stall regime, producing technical data to give aircraft designers a better understanding of aerodynamics, effectiveness of flight controls and thrust vectoring, and airflow phenomena at high angles of attack. Stall is a condition of an airplane or an airfoil in which lift decreases and drag increases due to the separation of airflow. Thrust vectoring compensates for the loss of control through normal aerodynamic surfaces that occurs during a stall. Post-stall refers to flying beyond the normal stall angle of attack, which in the X-31 was at a 30-degree angle of attack. During Dryden flight testing, the X-31 aircraft established several milestones. On November 6, 1992, the X-31 achieved controlled flight

  19. STS-66 Edwards Landing with Drag Chute

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The space shuttle Atlantis lands with its drag chute deployed on runway 22 at Edwards, California, to complete the STS-66 mission dedicated to the third flight of the Atmospheric Laboratory for Applications and Science-3 (ATLAS-3), part of NASA's Mission to Planet Earth program. The astronauts also deployed and retrieved a free-flying satellite designed to study the middle and lower thermospheres and perform a series of experiments covering life sciences research and microgravity processing. The landing was at 7:34 a.m. (PST) 14 November 1994, after being waved off from the Kennedy Space Center, Florida, due to adverse weather. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout the mission. They are then removed after the Space Shuttle returns to

  20. Sir Charles Edward Saunders, Dominion cerealist.

    PubMed

    Morrison, Malcolm J

    2008-06-01

    Charles Edward Saunders was born in London, Ontario, in 1867. His father, Sir William Saunders, was the first director of the Dominion Experimental Farms (1886-1911). Charles received his B.A. with honours in science from the University of Toronto in 1888 and his Ph.D. in chemistry from Johns Hopkins University in Baltimore, Maryland, in 1891. He attempted a career in music, his first love, from 1893 to 1902. With his father, Charles attended the 1902 International Conference on Plant Breeding and Hybridization in New York, where he learned of Mendel's theories of inheritance and their applicability to plant breeding. When he began work in 1903 in the Division of Cereal Breeding and Experimentation at the Central Experimental Farm in Ottawa, he used the knowledge he had gained at that conference. It was Charles's goal to achieve "fixity" in the varieties that had been bred and released using phenotypic mass selection, prior to his tenure as Cerealist. He selected four heads from the wheat variety Markham and in the winter of 1904 he performed a "chewing test" to select for gluten elasticity and colour. Seeds from two heads were chosen, and seeds from one went on to produce the variety Marquis after extensive yield trials on the Prairies. Marquis was 7 to 10 days earlier than Red Fife, the standard bread wheat of the Prairies. The earliness and tremendous yield of Marquis wheat resulted in the rapid and successful settlement of the Great Plains and countless billions of dollars in revenue to Canada. By 1923, 90% of the spring wheat in Canada and 70% in the USA was Marquis. Charles continued as Dominion Cerealist until his retirement in 1922. He was knighted in 1934, and died in 1937.

  1. Sir Charles Edward Saunders, Dominion cerealist.

    PubMed

    Morrison, Malcolm J

    2008-06-01

    Charles Edward Saunders was born in London, Ontario, in 1867. His father, Sir William Saunders, was the first director of the Dominion Experimental Farms (1886-1911). Charles received his B.A. with honours in science from the University of Toronto in 1888 and his Ph.D. in chemistry from Johns Hopkins University in Baltimore, Maryland, in 1891. He attempted a career in music, his first love, from 1893 to 1902. With his father, Charles attended the 1902 International Conference on Plant Breeding and Hybridization in New York, where he learned of Mendel's theories of inheritance and their applicability to plant breeding. When he began work in 1903 in the Division of Cereal Breeding and Experimentation at the Central Experimental Farm in Ottawa, he used the knowledge he had gained at that conference. It was Charles's goal to achieve "fixity" in the varieties that had been bred and released using phenotypic mass selection, prior to his tenure as Cerealist. He selected four heads from the wheat variety Markham and in the winter of 1904 he performed a "chewing test" to select for gluten elasticity and colour. Seeds from two heads were chosen, and seeds from one went on to produce the variety Marquis after extensive yield trials on the Prairies. Marquis was 7 to 10 days earlier than Red Fife, the standard bread wheat of the Prairies. The earliness and tremendous yield of Marquis wheat resulted in the rapid and successful settlement of the Great Plains and countless billions of dollars in revenue to Canada. By 1923, 90% of the spring wheat in Canada and 70% in the USA was Marquis. Charles continued as Dominion Cerealist until his retirement in 1922. He was knighted in 1934, and died in 1937. PMID:18521125

  2. Annual parallax and a dimming event of a Mira variable star, FV Bootis

    NASA Astrophysics Data System (ADS)

    Kamezaki, Tatsuya; Nakagawa, Akiharu; Omodaka, Toshihiro; Inoue, Kan-ichiro; Chibueze, James O.; Nagayama, Takumi; Ueno, Yuji; Matsunaga, Noriyuki

    2016-10-01

    We present the first measurement of the trigonometric parallax of water masers associated with a Mira star, FV Bootis (FV Boo) using VLBI Exploration of Radio Astrometry (VERA). Based on our multi-epoch VERA observations, we derived the parallax to be 0.97 ± 0.06 mas, which corresponds to a distance of 1.03^{+0.07}_{-0.06} kpc. The water masers around FV Boo were spatially distributed over an area of 41 au × 41 au, and their internal motions indicate the presence of an outflow. Using the Kagoshima University 1 m optical/infrared telescope, we determined the period to be 305.6 d and the mean apparent magnitude to be +2.91 mag in the K'-band. On the period-luminosity plane, the obtained period and K'-band magnitude puts FV Boo slightly below the sequence of Miras, possibly due to circumstellar reddening. Combining our photometric data with COBE and 2MASS datasets spanning over 20 years, we found in the near infrared that FV Boo was significantly fainter in 2005 compared with preceding and later phases. Its color, however, did not show a large variation through this change. We infer that the dimming could be caused by an eclipse due to a cloud in a binary system.

  3. Angular Size Measurements of Mira Variable Stars at 2.2 Microns. II.

    NASA Astrophysics Data System (ADS)

    van Belle, G. T.; Thompson, R. R.; Creech-Eakman, M. J.

    2002-09-01

    We present angular size measurements of 22 oxygen-rich Mira variable stars. These data are part of a long-term observational program using the Infrared Optical Telescope Array to characterize the observable behavior of these stars. Complementing the infrared angular size measurements, values for variable star phase, spectral type, bolometric flux, and distance were established for stars in the sample; flux and distance led to values for effective temperature (Teff) and linear radius, respectively. Additionally, values for the K-[12] color excess were established for these stars, which is indicative of dusty mass loss. Stars with higher color excess are shown to be systematically 120 Rsolar larger than their low color excess counterparts, regardless of period. This analysis appears to present a solution to a long-standing question presented by the evidence that some Mira angular diameters are indicative of first-overtone pulsation, while other diameters are more consistent with fundamental pulsation. A simple examination of the resultant sizes of these stars in the context of pulsation mode is consistent with at least some of these objects pulsating in the fundamental mode.

  4. Annual parallax and a dimming event of a Mira variable star, FV Bootis

    NASA Astrophysics Data System (ADS)

    Kamezaki, Tatsuya; Nakagawa, Akiharu; Omodaka, Toshihiro; Inoue, Kan-ichiro; Chibueze, James O.; Nagayama, Takumi; Ueno, Yuji; Matsunaga, Noriyuki

    2016-08-01

    We present the first measurement of the trigonometric parallax of water masers associated with a Mira star, FV Bootis (FV Boo) using VLBI Exploration of Radio Astrometry (VERA). Based on our multi-epoch VERA observations, we derived the parallax to be 0.97 ± 0.06 mas, which corresponds to a distance of 1.03^{+0.07}_{-0.06} kpc. The water masers around FV Boo were spatially distributed over an area of 41 au × 41 au, and their internal motions indicate the presence of an outflow. Using the Kagoshima University 1 m optical/infrared telescope, we determined the period to be 305.6 d and the mean apparent magnitude to be +2.91 mag in the K'-band. On the period-luminosity plane, the obtained period and K'-band magnitude puts FV Boo slightly below the sequence of Miras, possibly due to circumstellar reddening. Combining our photometric data with COBE and 2MASS datasets spanning over 20 years, we found in the near infrared that FV Boo was significantly fainter in 2005 compared with preceding and later phases. Its color, however, did not show a large variation through this change. We infer that the dimming could be caused by an eclipse due to a cloud in a binary system.

  5. High-angular-resolution stellar imaging with occultations from the Cassini spacecraft - III. Mira

    NASA Astrophysics Data System (ADS)

    Stewart, Paul N.; Tuthill, Peter G.; Nicholson, Philip D.; Hedman, Matthew M.

    2016-04-01

    We present an analysis of spectral and spatial data of Mira obtained by the Cassini spacecraft, which not only observed the star's spectra over a broad range of near-infrared wavelengths, but was also able to obtain high-resolution spatial information by watching the star pass behind Saturn's rings. The observed spectral range of 1-5 microns reveals the stellar atmosphere in the crucial water-bands which are unavailable to terrestrial observers, and the simultaneous spatial sampling allows the origin of spectral features to be located in the stellar environment. Models are fitted to the data, revealing the spectral and spatial structure of molecular layers surrounding the star. High-resolution imagery is recovered revealing the layered and asymmetric nature of the stellar atmosphere. The observational data set is also used to confront the state-of-the-art cool opacity-sampling dynamic extended atmosphere models of Mira variables through a detailed spectral and spatial comparison, revealing in general a good agreement with some specific departures corresponding to particular spectral features.

  6. Are anticoagulant independent mechanical valves within reach—fast prototype fabrication and in vitro testing of innovative bi-leaflet valve models

    PubMed Central

    Siegel, Rolland

    2015-01-01

    Background Exploration for causes of prosthetic valve thrombogenicity has frequently focused on forward or post-closure flow detail. In prior laboratory studies, we uncovered high amplitude flow velocities of short duration close to valve closure implying potential for substantial shear stress with subsequent initiation of blood coagulation pathways. This may be relevant to widely accepted clinical disparity between mechanical and tissue valves vis-à-vis thrombogenicity. With a series of prototype bi-leaflet mechanical valves, we attempt reduction of closure related velocities with the objective of identifying a prototype valve with thrombogenic potential similar to our tissue valve control. This iterative design approach may find application in preclinical assessment of valves for anticoagulation independence. Methods Tested valves included: prototype mechanical bi-leaflet BVs (n=56), controls (n=2) and patented early prototype mechanicals (n=2) from other investigators. Pulsatile and quasi-steady flow systems were used for testing. Projected dynamic valve area (PDVA) was measured using previously described novel technology. Flow velocity over the open and closing periods was determined by volumetric flow rate/PDVA. For the closed valve interval, use was made of data obtained from quasi-steady back pressure/flow tests. Performance was ranked by a proposed thrombogenicity potential index (TPI) relative to tissue and mechanical control valves. Results Optimization of the prototype valve designs lead to a 3-D printed model (BV3D). For the mitral/aortic site, BV3D has lower TPI (1.10/1.47) relative to the control mechanical valve (3.44/3.93) and similar to the control tissue valve (ideal TPI ≤1.0). Conclusions Using unique technology, rapid prototyping and thrombogenicity ranking, optimization of experimental valves for reduced thrombogenic potential was expedited and simplified. Innovative mechanical valve configurations were identified that merit consideration

  7. Occasional Addresses by Edward Teller at Conferences of Laser Interaction and Related Plasma Phenomena (LIRPP)

    NASA Astrophysics Data System (ADS)

    Hora, Heinrich; Miley, George H.

    2016-10-01

    The following sections are included: * Futurology of High Intensity Lasers (LIRPP Vol. 3A) * Lecture in Connection with the Edward Teller Medal Award (LIRPP Vol. 10) * Photo of the First Recipients of the Edward Teller Medal in 1991 * Photos from the Edward Teller Medal Celebration in 1997 * Photo with Participants of the LIRPP No. 12 Conference, 1995 * Photo with Edward Teller Medalists at IFSA01, Kyoto, 2001 * Keynote Address: The Edward Teller Lecture (LIRPP Vol. 11) * Keynote Address: Dr. Edward Teller (LIRPP Vol. 12) * Teller Award Presentation and Keynote Address (LIRPP Vol. 13) * Laudations of Awardees 1991-1995 (LIRPP Vol. 13) * Laudations of Awardees 1999-2003

  8. STS-67 Endeavour Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The space shuttle Endeavour slips to a smooth landing on runway 22 at Edwards, California, to complete the highly successful record-setting STS-67 mission. The landing was at 1:46 p.m. (PST) 18 March 1995, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather. Launched into space at 10:38 a.m. (PST) 1 March 1995, the Endeavour crew conducted NASA's longest shuttle flight to date and carried unique ultraviolet telescopes (ASTRO-2) which captured views of the universe impossible to obtain from the ground. Mission Commander was Steve Oswald making his third flight and the Pilot was Bill Gregory on his first mission. Mission Specialist 1 was John Grunsfeld making his first flight and Specialist 2 was Wendy Lawrence on her first flight. Tamara Jernigan served as Specialist 3 on her third flight and the two payload specialists were Samuel Durrance and Ronald Parise, both on their second flight. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads

  9. STS-66 Edwards Landing with Drag Chute

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The space shuttle Atlantis lands with its drag chute deployed on runway 22 at Edwards, California, to complete the STS-66 mission dedicated to the third flight of the Atmospheric Laboratory for Applications and Science-3 (ATLAS-3), part of NASA's Mission to Planet Earth program. The astronauts also deployed and retrieved a free-flying satellite designed to study the middle and lower thermospheres and perform a series of experiments covering life sciences research and microgravity processing. The landing was at 7:34 a.m. (PST) 14 November 1994, after being waved off from the Kennedy Space Center, Florida, due to adverse weather. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload bay throughout the mission. They are then removed after the Space Shuttle returns to

  10. STS-29 Landing Approach at Edwards

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The STS-29 Space Shuttle Discovery mission approaches for a landing at NASA's then Ames-Dryden Flight Research Facility, Edwards AFB, California, early Saturday morning, 18 March 1989. Touchdown was at 6:35:49 a.m. PST and wheel stop was at 6:36:40 a.m. on runway 22. Controllers chose the concrete runway for the landing in order to make tests of braking and nosewheel steering. The STS-29 mission was very successful, completing the launch a Tracking and Data Relay communications satellite, as well as a range of scientific experiments. Discovery's five man crew was led by Commander Michael L. Coats, and included pilot John E. Blaha and mission specialists James P. Bagian, Robert C. Springer, and James F. Buchli. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain inside the payload

  11. STS-37 Shuttle Crew after Edwards landing

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The crew of the Space Shuttle Atlantis gives the 'all's well' thumb's-up sign after leaving the 100-ton orbiter following their landing at 6:55 a.m. (PDT), 11 April 1991, at NASA's Ames Dryden Flight Research Facility (later redesignated Dryden Flight Research Center), Edwards, California, to conclude mission STS-37. They are, from left, Kenneth D. Cameron, pilot; Steven R. Nagel, mission commander; and mission specialists Linda M. Godwin, Jerry L. Ross, and Jay Apt. During the mission,which began with launch April 5 at Kennedy Space Center, Florida, the crew deployed the Gamma Ray Observatory. Ross and Jay also carried out two spacewalks, one to deploy an antenna on the Gamma Ray Observatory and the other to test equipment and mobility techniques for the construction of the future Space Station. The planned five-day mission was extended one day because of high winds at Edwards. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space

  12. Mathematical Existence Results for the Doi-Edwards Polymer Model

    NASA Astrophysics Data System (ADS)

    Chupin, Laurent

    2016-07-01

    In this paper, we present some mathematical results on the Doi-Edwards model describing the dynamics of flexible polymers in melts and concentrated solutions. This model, developed in the late 1970s, has been used and extensively tested in modeling and simulation of polymer flows. From a mathematical point of view, the Doi-Edwards model consists in a strong coupling between the Navier-Stokes equations and a highly nonlinear constitutive law. The aim of this article is to provide a rigorous proof of the well-posedness of the Doi-Edwards model, namely that it has a unique regular solution. We also prove, which is generally much more difficult for flows of viscoelastic type, that the solution is global in time in the two dimensional case, without any restriction on the smallness of the data.

  13. Endeavour lands at Edwards AFB, ending mission STS-100

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA/Edwards AFB, Calif. -- With its drag chute deployed, Endeavour lands on runway 22 at Edwards Air Force Base, Calif., at 12:10:42 p.m. EDT after a mission of 11 days, 12 hours, 54 minutes to the International Space Station on mission STS-100. The orbiter and its crew of seven logged about 4.9 million statute miles in 186 orbits. Due to unfavorable weather conditions, landing at KSC was waved off. The landing marked the third consecutive landing at EAFB.

  14. First-Ever Census of Variable Mira-Type Stars in Galaxy Outside the Local Group

    NASA Astrophysics Data System (ADS)

    2003-05-01

    First-Ever Census of Variable Mira-Type Stars in Galaxy Outsidethe Local Group Summary An international team led by ESO astronomer Marina Rejkuba [1] has discovered more than 1000 luminous red variable stars in the nearby elliptical galaxy Centaurus A (NGC 5128) . Brightness changes and periods of these stars were measured accurately and reveal that they are mostly cool long-period variable stars of the so-called "Mira-type" . The observed variability is caused by stellar pulsation. This is the first time a detailed census of variable stars has been accomplished for a galaxy outside the Local Group of Galaxies (of which the Milky Way galaxy in which we live is a member). It also opens an entirely new window towards the detailed study of stellar content and evolution of giant elliptical galaxies . These massive objects are presumed to play a major role in the gravitational assembly of galaxy clusters in the Universe (especially during the early phases). This unprecedented research project is based on near-infrared observations obtained over more than three years with the ISAAC multi-mode instrument at the 8.2-m VLT ANTU telescope at the ESO Paranal Observatory . PR Photo 14a/03 : Colour image of the peculiar galaxy Centaurus A . PR Photo 14b/03 : Location of the fields in Centaurus A, now studied. PR Photo 14c/03 : "Field 1" in Centaurus A (visual light; FORS1). PR Photo 14d/03 : "Field 2" in Centaurus A (visual light; FORS1). PR Photo 14e/03 : "Field 1" in Centaurus A (near-infrared; ISAAC). PR Photo 14f/03 : "Field 2" in Centaurus A (near-infrared; ISAAC). PR Photo 14g/03 : Light variation of six variable stars in Centaurus A PR Photo 14h/03 : Light variation of stars in Centaurus A (Animated GIF) PR Photo 14i/03 : Light curves of four variable stars in Centaurus A. Mira-type variable stars Among the stars that are visible in the sky to the unaided eye, roughly one out of three hundred (0.3%) displays brightness variations and is referred to by astronomers as a

  15. Pollution by oestrogenic endocrine disruptors and β-sitosterol in a south-western European river (Mira, Portugal).

    PubMed

    Rocha, Maria João; Cruzeiro, Catarina; Reis, Mário; Pardal, Miguel Ângelo; Rocha, Eduardo

    2016-04-01

    The Mira River is a Portuguese water body widely known for its wilderness and is advertised as one of the less polluted European rivers. On this presumption, the levels of endocrine-disrupting compounds (EDCs) in Mira waters were never measured. However, because environmentalists have claimed that the Mira could be moderately polluted, a range of 17 EDCs were measured not only at the estuary but also along the river. The targeted EDCs included natural and pharmaceutical oestrogens (17β-oestradiol, oestrone and 17α-ethynylestradiol), industrial/household pollutants (octylphenols, nonylphenols and their monoethoxylates and diethoxylates and bisphenol A), phytoestrogens (formononetin, biochanin A, daidzein, genistein) and the phytosterol sitosterol (SITO). For this propose, waters from six sampling sites were taken every 2 months, over a 1-year period (2011), and analysed by gas chromatography-mass spectrometry. Unexpectedly high levels of oestrogens and of industrial/household pollutants were measured at all sampling sites, including those located inside natural protected areas. Indeed, the annual average sum of EDCs was ≈57 ng/L for oestrogens and ≈1.3 μg/L for industrial/household chemicals. In contrast, the global average levels of phytoestrogens (≈140 ng/L) and of SITO (≈295 ng/L) were lower than those reported worldwide. The EDC concentrations were normalised for ethynylestradiol equivalents (EE2eq). In view of these, the oestrogenic load of the Mira River attained ≈47 ng/L EE2eq. In addition, phosphates were above legal limits at both spring and summer (>1 mg/L). Overall, data show EDCs at toxicant relevant levels in the Mira and stress the need to monitor rivers that are allegedly less polluted.

  16. Pollution by oestrogenic endocrine disruptors and β-sitosterol in a south-western European river (Mira, Portugal).

    PubMed

    Rocha, Maria João; Cruzeiro, Catarina; Reis, Mário; Pardal, Miguel Ângelo; Rocha, Eduardo

    2016-04-01

    The Mira River is a Portuguese water body widely known for its wilderness and is advertised as one of the less polluted European rivers. On this presumption, the levels of endocrine-disrupting compounds (EDCs) in Mira waters were never measured. However, because environmentalists have claimed that the Mira could be moderately polluted, a range of 17 EDCs were measured not only at the estuary but also along the river. The targeted EDCs included natural and pharmaceutical oestrogens (17β-oestradiol, oestrone and 17α-ethynylestradiol), industrial/household pollutants (octylphenols, nonylphenols and their monoethoxylates and diethoxylates and bisphenol A), phytoestrogens (formononetin, biochanin A, daidzein, genistein) and the phytosterol sitosterol (SITO). For this propose, waters from six sampling sites were taken every 2 months, over a 1-year period (2011), and analysed by gas chromatography-mass spectrometry. Unexpectedly high levels of oestrogens and of industrial/household pollutants were measured at all sampling sites, including those located inside natural protected areas. Indeed, the annual average sum of EDCs was ≈57 ng/L for oestrogens and ≈1.3 μg/L for industrial/household chemicals. In contrast, the global average levels of phytoestrogens (≈140 ng/L) and of SITO (≈295 ng/L) were lower than those reported worldwide. The EDC concentrations were normalised for ethynylestradiol equivalents (EE2eq). In view of these, the oestrogenic load of the Mira River attained ≈47 ng/L EE2eq. In addition, phosphates were above legal limits at both spring and summer (>1 mg/L). Overall, data show EDCs at toxicant relevant levels in the Mira and stress the need to monitor rivers that are allegedly less polluted. PMID:27004433

  17. Development of LM10-MIRA LOX/LNG expander cycle demonstrator engine

    NASA Astrophysics Data System (ADS)

    Rudnykh, Mikhail; Carapellese, Stefano; Liuzzi, Daniele; Arione, Luigi; Caggiano, Giuseppe; Bellomi, Paolo; D'Aversa, Emanuela; Pellegrini, Rocco; Lobov, S. D.; Gurtovoy, A. A.; Rachuk, V. S.

    2016-09-01

    This article contains results of joint works by Konstruktorskoe Buro Khimavtomatiki (KBKhA, Russia) and AVIO Company (Italy) on creation of the LM10-MIRA liquid-propellant rocket demonstrator engine for the third stage of the upgraded "Vega" launcher.Scientific and research activities conducted by KBKhA and AVIO in 2007-2014 in the frame of the LYRA Program, funded by the Italian Space Agency, with ELV as Prime contractor, and under dedicated ASI-Roscosmos inter-agencies agreement, were aimed at development and testing of a 7.5 t thrust expander cycle demonstrator engine propelled by oxygen and liquid natural gas (further referred to as LNG).

  18. SMOS L1PP Performance Analysis with MIRAS Data from Validation Campaigns

    NASA Astrophysics Data System (ADS)

    Castro, R.; Barbosa, J.; Candeias, H.; Catarino, N.; Freitas, J.; Freitas, S.; Gutierrez, A.; Lucas, B.

    2009-04-01

    Deimos Engenharia has been involved in the SMOS mission since 2003 and has played an important role in the project since then. The two main software packages that Deimos Engenharia has maintained during the past years are a) the Level 1 Processor Prototype (L1PP), where the scientific algorithms are implemented and verified; and b) the SMOS End-to-end Performance Simulator - Ground Segment (SEPS-GS), derived from the original simulator from the Universitat Politécnica de Catalunya (UPC) but with emphasis on Ground Segment capabilities. These tools have been widely used by the scientific community, as well as by the Deimos Engenharia's SMOS team, in preparation for the operational period of the SMOS mission. In May/June 2007, Image Validation Tests (IVT) were conducted in the Maxwell Anechoic Chamber at ESA/ESTEC, in Noordwijck. This campaign provided the first set of data available measured by the MIRAS instrument itself, instead of being generated by the SEPS-GS simulator. This data has now been extensively analysed by Deimos Engenharia, and several studies have been performed and released, aiming at the validation and improvement of the L1PP. The results have shown to be in good agreement with the theoretical expectations, confirming that the L1PP is well prepared for the upcoming commissioning phase. The IVT data analysis was mainly based on the study of reconstructed flat scenes obtained in the Maxwell chamber. This allowed the test of several optional calibration algorithms and alternative methods for image reconstruction and foreign sources removal. The L1PP was adapted specifically for the analysis of IVT data, through the implementation of a Near Field reconstruction algorithm. The Level 1 processing has then been evaluated with real data taken with MIRAS. The results have been consistently better than expected, since the theoretically predicted value for the radiometric accuracy (or pixel bias) of an averaged flat scene is estimated to be roughly 1 K and

  19. Quality in Higher Education: The Contribution of Edward Demings Principles

    ERIC Educational Resources Information Center

    Redmond, Richard; Curtis, Elizabeth; Noone, Tom; Keenan, Paul

    2008-01-01

    Purpose--There can be little doubt about the importance and relevance of quality for any service industry. One of the most influential contributors to service quality developments was W. Edwards Deming (1900-1993). An important component of Demings philosophy is reflected in his 14-principles for transforming a service as they indicate what…

  20. Introducing Edward L. Bernays, the "Father of Public Relations."

    ERIC Educational Resources Information Center

    Yeager, Robert J.

    1985-01-01

    Relates some of the public relations achievements and techniques of Edward L. Bernays. Sees modern public relations proceeding from an understanding of individuals, institutions and social groups, and their interrelationships. Considers the information dissemination, persuasion, and attitude integration functions of public relations. Lists…

  1. Public Educators as Interpretive Critics: Edward Said and Raymond Williams

    ERIC Educational Resources Information Center

    Nixon, Jon

    2008-01-01

    The work of Edward Said and Raymond Williams exemplifies an important aspect of the role of the public intellectual as educator. This paper concentrates on the significance of their work as public educators and on the tradition of interpretive criticism as they developed it within the field of literary and cultural theory. The argument builds from…

  2. Edward Jenner, MD, and the scourge that was.

    PubMed

    White, P J; Shackelford, P G

    1983-09-01

    This article was inspired by the global eradication of smallpox in 1980. Rather than reiterate the recent history of this remarkable achievement, we have chosen to celebrate the event by reviewing the early history of smallpox immunization and the contribution of Edward Jenner, MD, to this endeavor. In addition, we present these historical events within the context of knowledge acquired by modern virologists.

  3. Dr. Edward de Bono's Six Thinking Hats and Numeracy

    ERIC Educational Resources Information Center

    Paterson, Anne

    2006-01-01

    In education, the term "metacognition" describes thinking about thinking. Within mathematics, the term "metacomputation" describes thinking about computational methods and tools. This article shows how Dr. Edward de Bono's Six Thinking Hats can be used to demonstrate metacognition and metacomputation in the primary classroom. The article suggests…

  4. What's Wrong with "Edward the Unready"? Our Responsibility for Readiness.

    ERIC Educational Resources Information Center

    Graue, M. Elizabeth

    1998-01-01

    Describes how Rosemary Wells's new books about "Edward Unready" explain children and readiness; explores the problems with her message, and suggests new endings that are more supportive of all children. Asserts that variability in development should not be mistaken for deficit, and recommends changing the focus from judging children to judging…

  5. Edward Teller and Nuclei:. Along the Trail to the Neutrino

    NASA Astrophysics Data System (ADS)

    Haxton, W. C.

    2010-01-01

    I discuss two of Edward Teller's contributions to nuclear physics, the introduction of the Gamow-Teller operator in β decay and the formulation of the Goldhaber-Teller model for electric dipole transitions, in the context of efforts to understand the weak interaction and the nature of the neutrino.

  6. Transcatheter treatment of Starr-Edwards paravalvular leaks.

    PubMed

    Santoro, Giuseppe; Scognamiglio, Giancarlo; Gaio, Gianpiero; Iacono, Carola; Giugno, Luca; Russo, Maria G

    2014-06-28

    A 56-year-old patient was referred because of refractory heart failure and mild haemolysis caused by multiple, severe paravalvular leaks of a Starr-Edwards valve implanted in mitral position 23 years before. Owing to perceived high risk of surgical re-valving, percutaneous paravalvular leak occlusion was performed by implantation of multiple, simultaneously deployed Amplatzer Vascular Plugs.

  7. The development of the Starr-Edwards heart valve.

    PubMed Central

    Matthews, A M

    1998-01-01

    Development of the Starr-Edwards heart valve marked a new era in the treatment of valvular heart disease. Until the development of the Starr-Edwards valve, there were no published reports of patients who had lived longer than 3 months with a prosthetic valve in the mitral position. This valve was the result of a unique partnership between a young surgeon, Dr. Albert Starr, and an experienced engineer, Mr. Lowell Edwards. Working as a team, these 2 men developed and successfully implanted the 1st Starr-Edwards valve within less than 2 years of their 1st meeting. Their key to success was their willingness and ability to make repeated modifications to their design to solve each clinical problem as it arose. Their constant focus on the clinical goal aided the rapid transformation of their design from a leaflet valve to a shielded ball valve, and finally to an unshielded ball valve suitable for implantation in a human being. Along the way, they abandoned the idea of imitating the appearance of native valves, in favor of developing valves that would be clinically successful. Their work has provided help and hope for patients who otherwise would have died from the complications of rheumatic heart disease and other valvular disorders for which valve replacement is the only treatment. Images PMID:9885105

  8. The Small Rural Schools of Prince Edward Island.

    ERIC Educational Resources Information Center

    Edmonds, E. L.

    In 1973, there were 56 one- and two-room elementary schools in Prince Edward Island (Canada). As part of a descriptive survey of these schools, now closed by consolidation, researchers visited each school in 1973 and recorded details of the buildings, facilities, and school organizations. Teachers from 47 schools and their 737 students in grades…

  9. A tumor profile in Edwards syndrome (trisomy 18).

    PubMed

    Satgé, Daniel; Nishi, Motoi; Sirvent, Nicolas; Vekemans, Michel

    2016-09-01

    Constitutional trisomy 18 causes Edwards syndrome, which is characterized by intellectual disability and a particular set of malformations. Although this condition carries high mortality during prenatal and early postnatal life, some of the rare infants who survive the first months develop benign and malignant tumors. To determine the tumor profile associated with Edwards syndrome, we performed a systematic review of the literature. This review reveals a tumor profile differing from those of Down (trisomy 21) and Patau (trisomy 13) syndromes. The literature covers 45 malignancies: 29 were liver cancers, mainly hepatoblastomas found in Japanese females; 13 were kidney tumors, predominantly nephroblastomas; 1 was neuroblastoma; 1 was a Hodgkin disease; and 1 was acute myeloid leukemia in an infant with both trisomy 18 and type 1 neurofibromatosis. No instances of the most frequent malignancies of early life-cerebral tumors, germ cell tumors, or leukemia--are reported in children with pure trisomy 18. Tumor occurrence does not appear to correlate with body weight, tissue growth, or cancer genes mapping to chromosome 18. Importantly, the most recent clinical histories report successful treatment; this raises ethical concerns about cancer treatment in infants with Edwards syndrome. In conclusion, knowledge of the Edwards' syndrome tumor profile will enable better clinical surveillance in at-risk organs (i.e., liver, kidney). This knowledge also provides clues to understanding oncogenesis, including the probably reduced frequency of some neoplasms in infants and children with this genetic condition. © 2016 Wiley Periodicals, Inc. PMID:27474103

  10. STS-66 landing at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The drag chute is fully deployed as the Space Shuttle Atlantis heads toward a stop at Edwards Air Force Base in southern California, ending a successful 10 day, 22 hour and 34 minute space mission. Landing occured at 7:34 a.m. (PST), November 14, 1994.

  11. STS-66 landing at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The main landing gear is on the ground and the nose gear is about to touch down as the Space Shuttle Atlantis heads toward a stop at Edwards Air Force Base in southern California, ending a successful 10 day, 22 hour and 34 minute space mission. Landing occured at 7:34 a.m. (PST), November 14, 1994.

  12. STS-67 landing at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The drag chute is fully deployed in this view of the Space Shuttle Endeavour as it completes a mission of almost 17 days duration in space on runway 22 at Edwards Air Force Base in southern California. Landing occurred at 1:46 p.m. (EST), March 18, 1995.

  13. STS-67 landing at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The Space Shuttle Endeavour, after completing a mission of almost 17 days duration in space, touches down on runway 22 at Edwards Air Force Base in southern California. Landing occurred at 1:46 p.m. (EST), March 18, 1995. In this photo the nose gear is still in the air as the orbiter touches down.

  14. Edward Lear, Limericks, and Nonsense: A Little Nonsense. [Lesson Plan].

    ERIC Educational Resources Information Center

    2002

    British poet Edward Lear (1812-1888) is widely recognized as the father of the limerick form of poetry and is well known for his nonsense poems. In the first lesson for grades 3-5, which focuses on Lear's nonsense poem "The Owl and the Pussy Cat," students learn about nonsense poetry as well as the various poetic techniques and devices that poets…

  15. Reception of Edward Bernays' Doctrine of "Manipulating Public Opinion."

    ERIC Educational Resources Information Center

    Olasky, Marvin N.

    Ivy Lee and Edward Bernays are generally regarded as the founding fathers of modern public relations. While Lee has been the subject of a full biography that included contemporary reaction to his ideas, there has been no similar work on how Bernays' ideas were received, though his ideas were in some ways more radical. He believed that propaganda…

  16. Mary Edwards Walker: the soul ahead of her time.

    PubMed

    Rehman, Atiq; Rahman, Naba G; Harris, Sharon M; Cheema, Faisal H

    2015-02-01

    Mary Edwards Walker was a gallant woman who stood for women's rights, embodied the true American spirit, and served the Union Army in the Civil War as a surgeon. She later became the first and only woman in United States history to be awarded the Congressional Medal of Honor. PMID:25535874

  17. Parallax of a Mira variable R Ursae Majoris studied with astrometric VLBI

    NASA Astrophysics Data System (ADS)

    Nakagawa, Akiharu; Kurayama, Tomoharu; Matsui, Makoto; Omodaka, Toshihiro; Honma, Mareki; Shibata, Katsunori M.; Sato, Katsuhisa; Jike, Takaaki

    2016-10-01

    We have measured an annual parallax of the Mira variable R Ursae Majoris (R UMa) with the VLBI Exploration for Radio Astronomy (VERA). From the monitoring VLBI observations over a span of about two years, we detected H2O maser spots in the LSR velocity range from 37 to 42 km s-1. We derived an annual parallax of 1.97 ± 0.05 mas, and this gives a corresponding distance of 508 ± 13 pc. The VLBI maps revealed 72 maser spots distributed in an ˜110 au area around the expected stellar position. Circumstellar kinematics of the maser spots were also revealed by subtracting a systemic motion in the Hipparcos catalog from proper motions of each maser spot derived from our VLBI observations. Infrared photometry was also conducted to measure a K-band apparent magnitude, and we obtained a mean magnitude of mK = 1.19 ± 0.02 mag. Using the trigonometric distance, mK is converted to a K-band absolute magnitude of MK = -7.34 ± 0.06 mag. This result gives a much more accurate absolute magnitude for R UMa than previously provided. We solved a zero-point of the MK-log P relation for the Galactic Mira variables and obtained a relation of MK = -3.52 log P + (1.09 ± 0.14). Other long-period variables, including red supergiants, whose distances were determined with astrometric VLBI, were also compiled to explore the different sequences of the MK-log P relation.

  18. Atlas of the mean light curves of the Mira-type stars

    NASA Astrophysics Data System (ADS)

    Kudashkina, L. S.; Andronov, I. L.

    For 62 Mira-type stars (best covered by the AAVSO observations published by Mattei (1979)) the mean curves have been fitted by trigonometric polynomials with an optimal number of harmonics (program by Andronov (1994)). The characteristics of the mean curve and of the individual harmonics are tabulated. The correlation analysis of the pairs of these mean characteristics is made. Among them: the amplitude r_j of the main wave (j = 1), trial (j-1)th harmonic in stellar magnitudes, phase phi_j of the maximum brightness of the trial wave, ratio r_j/r_1 of the amplitude of the amplitude of the harmonic to the amplitude of the main harmonic wave, shift phi_j-j phi_1 of the phase of the trial harmonic relatively to the main wave etc. have been calculated. Three diagrams have been considered: "period - (r_2/r_1)", "period - (phi_2 - phi_1)","(r_2 / r_1) - (phi_2 - phi_1)", where index "1" indicates a main wave. The majority of the stars exhibit negative shift of the phase of the first harmonic phi_2 with respect to the main wave phi_1. Maximal negative shifts of the phases are characteristic for the stars with values of the period P < 250^d and with P >= 400^d. Points with maximal positive phase shifts agree well with total picture for the negative ones. Twelve stars, which are characterized by symmetrical light curves (phi_2 - phi_1 = 0), form a homogeneous group according to their spectral types. This group corresponds to early spectral subclasses of type M (from M0 to M5). The more detailed analysis of the pairs of these and other mean characteristics allow to separate the Mira-type stars into the groups of homogeneous physical and evolutionary state. These groups are compared with that proposed by Mennessier (1985).

  19. Parallax of a Mira variable R Ursae Majoris studied with astrometric VLBI

    NASA Astrophysics Data System (ADS)

    Nakagawa, Akiharu; Kurayama, Tomoharu; Matsui, Makoto; Omodaka, Toshihiro; Honma, Mareki; Shibata, Katsunori M.; Sato, Katsuhisa; Jike, Takaaki

    2016-08-01

    We have measured an annual parallax of the Mira variable R Ursae Majoris (R UMa) with the VLBI Exploration for Radio Astronomy (VERA). From the monitoring VLBI observations over a span of about two years, we detected H2O maser spots in the LSR velocity range from 37 to 42 km s-1. We derived an annual parallax of 1.97 ± 0.05 mas, and this gives a corresponding distance of 508 ± 13 pc. The VLBI maps revealed 72 maser spots distributed in an ˜110 au area around the expected stellar position. Circumstellar kinematics of the maser spots were also revealed by subtracting a systemic motion in the Hipparcos catalog from proper motions of each maser spot derived from our VLBI observations. Infrared photometry was also conducted to measure a K-band apparent magnitude, and we obtained a mean magnitude of mK = 1.19 ± 0.02 mag. Using the trigonometric distance, mK is converted to a K-band absolute magnitude of MK = -7.34 ± 0.06 mag. This result gives a much more accurate absolute magnitude for R UMa than previously provided. We solved a zero-point of the MK-log P relation for the Galactic Mira variables and obtained a relation of MK = -3.52 log P + (1.09 ± 0.14). Other long-period variables, including red supergiants, whose distances were determined with astrometric VLBI, were also compiled to explore the different sequences of the MK-log P relation.

  20. Obituary: Harrison Edward Radford, 1927-2000

    NASA Astrophysics Data System (ADS)

    Moran, James Michael; Kirby, Kate Page; Chance, Kelly V.; Brown, Campbell

    2003-12-01

    Harrison Edward ``Harry" Radford, a noted laboratory spectroscopist and pioneer in the application of magnetic resonance techniques to spectroscopy, died on 5 May 2000, after a long battle with amyotropic lateral sclerosis (ALS). During a 37-year career at the National Bureau of Standards and the Smithsonian Astrophysical Observatory, Harry measured the frequencies of numerous molecular transitions which aided the emerging field of astrochemistry. Harry was both an excellent theoretician and a preeminently skilled experimentalist. He has several major spectroscopic achievements to his credit. He performed the first study of a short-lived molecular free radical, OH, by electron paramagnetic resonance spectroscopy, opening up a huge and important field of research. Together with colleagues he made the first observation of the rotational spectrum of CH by far infrared laser magnetic resonance spectroscopy and extended the technique to other molecules such as CH3O. Harry was born in Peterborough, New Hampshire, on 26 July 1927. He was the son of Harrison Edwin Radford, a roofer, and Dorothy (née Cole) Radford. He dropped out of high school to join the Navy in 1944 as an electronics technician's mate. After his discharge in 1946 he worked in the family construction business for four years as a roofer. In 1950 he entered the University of New Hampshire and graduated four years later, Summa Cum Laude, with a degree in physics. As a graduate student at Yale from 1954 to 1959 he wrote his PhD thesis under the supervision of V.W. Hughes on the microwave Zeeman spectra of oxygen and fluorine where he used the technique of paramagnetic resonance absorption in atomic vapors. In 1954 he married Mildred Spofford. They had three daughters, Susan (born in 1955), Amy (1957), and Sarah (1960). In 1974 he married Alfa Goldthwaithe Morrison, who survived him. From 1959 until 1969 Harry worked at the National Bureau of Standards (now the National Institute of Standards and Technology

  1. Obituary: Donald Edward Osterbrock, 1924-2007

    NASA Astrophysics Data System (ADS)

    Veilleux, Sylvain

    2007-12-01

    Donald Edward Osterbrock, one of the leading figures of post-World War II astronomy, died suddenly of a heart attack on 11 January 2007, while walking near his office at the University of California, Santa Cruz. He was 82 years old. His initials spelled D.E.O. (God in latin!), but he was known simply as Don to his many friends and colleagues. Don's long and productive career spanned five decades. His scientific work helped shape our understanding of lower main-sequence stars, the ionized interstellar medium, and active galactic nuclei. He was also a highly respected historian of astronomy who shed new light on 19th- and 20th-century astronomy. Don was born in Cincinnati, Ohio, on 13 July 1924. Both of his parents were of German descent and valued hard work, education, and science. They both completed their high-school education at night while working full-time during the day. His father eventually became a professor of electrical engineering at the University of Cincinnati. Don's plan to become an astronomer was put on hold when the Japanese attacked Pearl Harbor in 1941. After graduation from high school, Don joined the United States Army and trained as a meteorologist, taking all of the physics and mathematics courses required for a bachelor's degree in physics from the University of Chicago. He was eventually sent to islands in the Pacific Ocean but never was in harm's way. After three years of service, Don returned to Chicago to obtain his bachelor's degree in 1948, his M.S. in astronomy in 1949, and a Ph.D. in astronomy in 1952. Don's years at the University of Chicago and the University's Yerkes Observatory in Williams Bay, Wisconsin, were pivotal for his career and personal life. He came in contact with such luminaries as Otto Struve, Bengt Strömgren, Subrahmanyan Chandrasekhar, and William W. Morgan. At Yerkes, he also met and married Irene L. Hansen, a native of Williams Bay, who was employed as a member of the Yerkes staff. They had a son, William, now

  2. STS-67 Endeavour Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The space shuttle Endeavour slips to a smooth landing on runway 22 at Edwards, California, to complete the highly successful record-setting STS-67 mission. The landing was at 1:46 p.m. (PST) 18 March 1995, after waiving off from the Kennedy Space Center, Florida, earlier that morning due to adverse weather. Launched into space at 10:38 a.m. (PST) 1 March 1995, the Endeavour crew conducted NASA's longest shuttle flight to date and carried unique ultraviolet telescopes (ASTRO-2) which captured views of the universe impossible to obtain from the ground. Mission Commander was Steve Oswald making his third flight and the Pilot was Bill Gregory on his first mission. Mission Specialist 1 was John Grunsfeld making his first flight and Specialist 2 was Wendy Lawrence on her first flight. Tamara Jernigan served as Specialist 3 on her third flight and the two payload specialists were Samuel Durrance and Ronald Parise, both on their second flight. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads

  3. The origin and evolution of short-period Miras in the solar neighborhood: Constraints on the life cycle of old stars

    NASA Technical Reports Server (NTRS)

    Jura, M.

    1994-01-01

    The spatial distribution of the short-period (P less than 300 days) oxygen-rich Miras in the solar neighborhood can be fitted with an exponential scale height above the Galactic plane of about 600 pc. Using the Gliese catalog of local main-sequence stars, we estimate that the density of suitable G-type progenitor dwarfs within 20 pc of the Sun for these short-period Miras is 6 x 10(exp -4)/cu pc. The portion of the H-R diagram near the main-sequence turnoff of these velocity-selected Gliese stars is intermediate between that of the old open cluster NGC 188 and that of the metal-rich globular cluster, 47 Tuc. We infer that the main-sequence progenitors of the short-period Miras have masses near 1.0 solar mass, and we estimate that these Miras have ages approximately 9 x 10(exp 9). We also identify a few old disk red giants in the neighborhood of the Sun. On the basis of very limited information, we estimate that the total amount of mass lost from these stars during their first ascent up the red giant branch is less than or equal to 0.1 solar mass. We derive a duration of the short-period Mira phase of close to 5 x 10(exp 5) yr. This estimate for the duration of the short period Mira phase is longer than our estimate of 2 x 10(exp 5) yr for the duration of the Mira phase for stars with periods longer than 300 days. From their infrared colors, we estimate a typical mass-loss rate from the short-period Miras of approximately 1 x 10(exp -7) solar mass/yr.

  4. Obituary: Donald Edward Osterbrock, 1924-2007

    NASA Astrophysics Data System (ADS)

    Veilleux, Sylvain

    2007-12-01

    Donald Edward Osterbrock, one of the leading figures of post-World War II astronomy, died suddenly of a heart attack on 11 January 2007, while walking near his office at the University of California, Santa Cruz. He was 82 years old. His initials spelled D.E.O. (God in latin!), but he was known simply as Don to his many friends and colleagues. Don's long and productive career spanned five decades. His scientific work helped shape our understanding of lower main-sequence stars, the ionized interstellar medium, and active galactic nuclei. He was also a highly respected historian of astronomy who shed new light on 19th- and 20th-century astronomy. Don was born in Cincinnati, Ohio, on 13 July 1924. Both of his parents were of German descent and valued hard work, education, and science. They both completed their high-school education at night while working full-time during the day. His father eventually became a professor of electrical engineering at the University of Cincinnati. Don's plan to become an astronomer was put on hold when the Japanese attacked Pearl Harbor in 1941. After graduation from high school, Don joined the United States Army and trained as a meteorologist, taking all of the physics and mathematics courses required for a bachelor's degree in physics from the University of Chicago. He was eventually sent to islands in the Pacific Ocean but never was in harm's way. After three years of service, Don returned to Chicago to obtain his bachelor's degree in 1948, his M.S. in astronomy in 1949, and a Ph.D. in astronomy in 1952. Don's years at the University of Chicago and the University's Yerkes Observatory in Williams Bay, Wisconsin, were pivotal for his career and personal life. He came in contact with such luminaries as Otto Struve, Bengt Strömgren, Subrahmanyan Chandrasekhar, and William W. Morgan. At Yerkes, he also met and married Irene L. Hansen, a native of Williams Bay, who was employed as a member of the Yerkes staff. They had a son, William, now

  5. Revealing the importance of meristems and roots for the development of hypersensitive responses and full foliar resistance to Phytophthora infestans in the resistant potato cultivar Sarpo Mira.

    PubMed

    Orłowska, Elzbieta; Basile, Alessio; Kandzia, Izabela; Llorente, Briardo; Kirk, Hanne Grethe; Cvitanich, Cristina

    2012-08-01

    The defence responses of potato against Phytophthora infestans were studied using the highly resistant Sarpo Mira cultivar. The effects of plant integrity, meristems, and roots on the hypersensitive response (HR), plant resistance, and the regulation of PR genes were analysed. Sarpo Mira shoots and roots grafted with the susceptible Bintje cultivar as well as non-grafted different parts of Sarpo Mira plants were inoculated with P. infestans. The progress of the infection and the number of HR lesions were monitored, and the regulation of PR genes was compared in detached and attached leaves. Additionally, the antimicrobial activity of plant extracts was assessed. The presented data show that roots are needed to achieve full pathogen resistance, that the removal of meristems in detached leaves inhibits the formation of HR lesions, that PR genes are differentially regulated in detached leaves compared with leaves of whole plants, and that antimicrobial compounds accumulate in leaves and roots of Sarpo Mira plants challenged with P. infestans. While meristems are necessary for the formation of HR lesions, the roots of Sarpo Mira plants participate in the production of defence-associated compounds that increase systemic resistance. Based on the literature and on the presented results, a model is proposed for mechanisms involved in Sarpo Mira resistance that may apply to other resistant potato cultivars.

  6. 77 FR 17530 - Order Granting an Application of Edward Jones & Co. LLP Exemption From Exchange Act Section 11(d...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    ... COMMISSION Order Granting an Application of Edward Jones & Co. LLP Exemption From Exchange Act Section 11(d... for Edward Jones & Co., L.P. (``Edward Jones'') requested that the Securities and Exchange Commission (``Commission'') issue to Edward Jones an exemption from Section 11(d)(1) of the Securities Exchange Act of...

  7. Geologic framework and hydrogeologic characteristics of the outcrops of the Edwards and Trinity aquifers, Medina Lake area, Texas

    USGS Publications Warehouse

    Small, Ted A.; Lambert, Rebecca B.

    1998-01-01

    The Trinity aquifer, which crops out in the northern part of the Medina Lake area and underlies the Edwards aquifer in the southern part, is much less permeable and productive than the Edwards aquifer. Where the Trinity aquifer underlies the Edwards, the Trinity acts as a lower confining unit on the Edwards.

  8. Behavior of Mira Variables in Bandstrength-Color Diagrams. Comparison of Dynamic Models with Calibrated Spectral Scans

    NASA Astrophysics Data System (ADS)

    Wing, R. F.; Alvarez, R.; Plez, B.; Yuan, Y.

    We compare 26-color scanner observations of Mira variables (Wing 1967, recently rereduced and recalibrated) with model calculations. The measurements were made through a 30 AA exit slot at 26 selected wavelengths between 7800 and 11000 AA. They include the best available continuum points, and points sensitive to the presence of bands of TiO, VO, CN, ZrO, and H_2O. We present molecular bandstrength-color diagrams in which the variables execute loops. This behavior was first shown in a review article (Spinrad & Wing 1969) and discussed further by Wing (1980). Here we present comparisons with model calculations, following the work of Alvarez & Plez (1998). Detailed synthetic spectra from hydrostatic models reproduce the observed colors. The loops followed by the Mira variables in color-color diagrams are reasonably well reproduced by hydrodynamic model atmospheres. We show the effects of pulsation on the behavior of the different molecular bands seen in this spectral region.

  9. Endeavour lands at Edwards AFB, ending mission STS-100

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA/Edwards AFB, Calif. -- After landing at Edwards Air Force Base, Calif., the STS-100 crew poses for a photograph in front of orbiter Endeavour, which successfully launched them to the International Space Station and returned them to Earth. They are (left to right) Mission Specialists John Phillips, Umberto Guidoni and Chris Hadfield; Pilot Jeffrey Ashby; Commander Kent Rominger; and Mission Specialists Yuri Lonchakov and Scott Parazynski. Guidoni is with the European Space Agency, Hadfield with the Canadian Space Agency and Lonchakov with the Russian Aviation and Space Agency. The orbiter and crew logged about 4.9 million statute miles in 186 orbits. Due to unfavorable weather conditions, landing at KSC was waved off. The landing marked the third consecutive landing at EAFB.

  10. Brief Reflections on Edward Teller's Scientific Life at Livermore

    NASA Astrophysics Data System (ADS)

    Tarter, C. Bruce

    2010-01-01

    As George Miller indicated in his welcoming remarks the theme of today's symposium is the scientific and educational legacy of Edward Teller. I will say a few words about his activities in those areas during the 50 plus years he spent at the Livermore Laboratory, Sig Hecker will touch on his re-engagement with the Los Alamos Laboratory during the last couple of decades of his life, and then we will show you a video with excerpts from the Memorial Service we held on November 3, 2003 after he passed away in September of that year. On the video you will get to hear comments by many of the people who knew Edward throughout much of his life, Hans Bethe, John Wheeler, Harold Agnew and many others ...

  11. Effective Edwards-Wilkinson equation for single-file diffusion.

    PubMed

    Centres, P M; Bustingorry, S

    2010-06-01

    In this work, we present an effective discrete Edwards-Wilkinson equation aimed to describe the single-file diffusion process. The key physical properties of the system are captured defining an effective elasticity, which is proportional to the single particle diffusion coefficient and to the inverse squared mean separation between particles. The effective equation gives a description of single-file diffusion using the global roughness of the system of particles, which presents three characteristic regimes, namely, normal diffusion, subdiffusion, and saturation, separated by two crossover times. We show how these regimes scale with the parameters of the original system. Additional repulsive interaction terms are also considered and we analyze how the crossover times depend on the intensity of the additional terms. Finally, we show that the roughness distribution can be well characterized by the Edwards-Wilkinson universal form for the different single-file diffusion processes studied here.

  12. MIRAS characterization and monitoring during the SMOS In-Orbit Commissioning Phase

    NASA Astrophysics Data System (ADS)

    Corbella, I.; Torres, F.; Martin-Neira, M.; Duffo, N.; González-Gambau, V.; Camps, A.; Vall-Llossera, M.

    2009-04-01

    1 Introduction The Microwave Imaging Radiometer with Aperture Synthesis (MIRAS) is the single payload of the Soil Moisture and Ocean Salinity (SMOS) mission. The instrument was completed in early 2007 and thoroughly tested both in anechoic chamber and vacuum thermal chamber during 2007. It was integrated to the platform in early 2008 and re-tested, including compatibility, during 2008. At present, the whole satellite is stowed and waiting to be launched during 2009. In two weeks after launch, the satellite will be in the final orbit with all deployments completed. Then the In-Orbit Commissioning Phase will start, having an estimated duration of 5.5 months. During this phase, the instrument modes of operation will be systematically checked and the calibration parameters will be fully characterized in real conditions. Also, the first brightness temperature images will be obtained in order to assess the overall retrieval procedures including inversion. In the end, the objective of the In-Orbit Commissioning Phase is to provide verification that the payload meets the scientific requirements of the mission. The general design and planning of the In-Orbit Commissioning Phase is given in [1]. This abstract presents the foreseen activities to be performed during this phase by the UPC team. Just after the start of the In-Orbit Commissioning Phase, the instrument will be commanded to perform a sequence of operations oriented at providing a full characterization in terms of calibration parameters. The idea is to reproduce the results obtained during the tests carried out on ground [2]. In particular, the following issues will be covered: Thermal Stability: To provide understanding of both the intra-orbit and inter-orbit temperature variations. The instrument will be continuously operating during a number of orbits while all temperature sensors being monitored. Electrical Stability: To re-compute all internal calibration parameters (gains, offsets, receiver noise temperatures

  13. Selected Scientific and Technical Contributions of Edward C. Polhamus

    NASA Technical Reports Server (NTRS)

    Luckring, James M.

    2016-01-01

    Edward C. Polhamus joined the NACA Langley Research Center staff in 1944 and was active in a broad range of aerodynamic research related to high-speed aircraft technology, aerodynamic prediction methods, and cryogenic wind-tunnel development. This lecture will focus on his 'leading-edge suction analogy' for the prediction of vortex-lift effects on slender wings. Briefer treatment of his contributions to variable-sweep aircraft and cryogenic wind tunnels is also included.

  14. 1995 Edward Teller Lecture Patience and Optimism (LIRPP Vol. 12)

    NASA Astrophysics Data System (ADS)

    Miley, George H.

    2016-10-01

    Remarks made in the author's acceptance lecture for the 1995 Edward Teller Medal are presented and expanded. Topics covered include research on nuclear-pumped lasers, the first direct e-beam-pumped laser, direct energy conversion and advanced fuel fusion, plus recent work on inertial electrostatic confinement. "Patience" and "optimism" are viewed as essential elements needed by scientists following the "zig-zag" path to fusion energy production.

  15. Structural Failure of a Starr-Edwards Aortic Track Valve

    PubMed Central

    Ringel, Richard E.; Moulton, Anthony L.; Burns, Janet E.; Brenner, Joel I.; Berman, Michael A.

    1983-01-01

    Structural failure of a Model 2400 Starr-Edwards aortic track valve occurred suddenly, 4 years after implantation. At operation, the valve cage was removed from the descending aorta. Examination of the excised prosthesis disclosed minimal cloth wear and no evidence of infective growth; however, three struts were fractured above their insertion into the valve ring. To our knowledge, this type of valve malfunction has not been previously noted. Images PMID:15227160

  16. Acute dysfunction of Starr-Edwards mitral prostheses

    PubMed Central

    Gunstensen, John

    1971-01-01

    Four cases of acute dysfunction of Starr-Edwards mitral prostheses are recorded. The patients presented with sudden dysponea 4 to 18 months after apparently successful mitral valve replacement. The prosthetic valve dysfunction was caused by thrombus on the bare metal cage of the prosthesis. No warning thromboembolic phenomena had been recorded. Urgent replacement of the valve resulted in the survival of one patient. Images PMID:5576532

  17. Time-resolved DPIV analysis of vortex dynamics in a left ventricular model through bileaflet mechanical and porcine heart valve prostheses.

    PubMed

    Pierrakos, Olga; Vlachos, Pavios P; Telionis, Demetri P

    2004-12-01

    The performance of the heart after a mitral valve replacement operation greatly depends on the flow character downstream of the valve. The design and implanting orientation of valves may considerably affect the flow development. A study of the hemodynamics of two orientations, anatomical and anti-anatomical, of the St. Jude Medical (SJM) bileaflet valve are presented and compared with those of the SJM Biocor porcine valve, which served also to represent the natural valve. We document the velocity field in a flexible, transparent (LV) using time-resolved digital particle image velocimetry (TRDPIV). Vortex formation and vortex interaction are two important physical phenomena that dominate the filling and emptying of the ventricle. For the three configurations, the following effects were examined: mitral valve inlet jet asymmetry, survival of vortical structures upstream of the aortic valve, vortex-induced velocities and redirection of theflow in abidance of the Biot-Savart law, domain segmentation, resonant times of vortical structures, and regions of stagnantflow. The presence of three distinct flow patterns, for the three configurations, was identified by the location of vortical structures and level of coherence corresponding to a significant variation in the turbulence level distribution inside the LV. The adverse effect of these observations could potentially compromise the efficiency of the LV and result in flow patterns that deviate from those in the natural heart. PMID:15796330

  18. A case of Starr-Edwards valve thrombosis in pregnancy.

    PubMed

    Davis, Margot; Kiess, Marla; Rychel, Valerie; Fofonoff, Doreen; Grewal, Jasmine

    2012-11-01

    Starr-Edwards ball-in-cage prosthetic heart valves, although durable, are associated with a particularly high rate of thromboembolic complications. This valve is seldom used in North America, and is certainly not the valve of choice in a woman of childbearing age. Few reports exist from the 1970s of thrombotic complications in pregnant women with Starr-Edwards prostheses, and the optimal management strategy for such valves is unclear. Here, the case is reported of a 31-year-old woman with a Starr-Edwards prosthesis in the mitral position who was transferred to the authors' center at six weeks' gestation with pulmonary edema. Transthoracic echocardiography demonstrated thrombosis of the prosthetic valve, with a mean gradient of 23 mmHg. When treated initially with intravenous heparin and furosemide the patient improved significantly; however, the optimal management going forward was unclear. Here, the options for anticoagulation during pregnancy and for management in the event of valve thrombosis are reviewed. In the absence of any clear guidelines, a thorough discussion of the various risks and benefits with the patient is necessary, but ultimately any consideration of the risk to the mother is paramount.

  19. Photographic copy of photograph, view looking northeast of JPL Edwards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, view looking northeast of JPL Edwards Test Station as it looked in 1945. To the immediate right of the Test Stand 'A' tower stands a concrete monitor building or blockhouse (now Building 4203/E-4) for observation and control of tests. Other frame buildings housed workshop and administrative functions. Long structure behind automobiles was designated 4207/E-8 and was used for instrument repair and storage, a cafeteria, machine and welding shops. To the immediate south of 4207/E-8 were 4200/E-1 (used as an office and photographic laboratory) and 4205/E-6 (guardhouse, with fire extinguisher mounted on it). To the northeast of 4205/E-6 was 4204/E-5 (a propellant storage dock, with shed roof). Buildings 4200/E-1, 4205/E-6 and 4207/E-8 were demolished in 1983. Note the absence of trees. (JPL negative no. 383-1297, July 1946) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  20. Morphology and kinematics of the gas envelope of the Mira binary W Aquilae

    NASA Astrophysics Data System (ADS)

    Thi Hoai, Do; Tuyet Nhung, Pham; Diep, Pham Ngoc; Thi Phuong, Nguyen; Tuan-Anh, Pham; Thi Thao, Nguyen; Darriulat, Pierre

    2016-07-01

    We analyse ALMA observations of the 12CO(3-2) emission of the circumstellar envelope (CSE) of the Mira variable binary star W Aql. These provide, for the first time, spatially resolved Doppler velocity spectra of the CSE up to angular distances to the central star of ∼ 5″ (meaning some 2000 AU). The exploratory nature of the observations (only five minutes in each of two different configurations) does not allow for a detailed modelling of the properties of the CSE but provides important qualitative information on its morphology and kinematics. Emission is found to be enhanced along an axis moving from east/west to north-east/south-west when the angular distance from the central star projected on the plane of the sky increases from zero to four arcseconds. In parallel, the Doppler velocity distribution displays asymmetry along an axis moving from east/west to north-west/south-east. The results are discussed in the context of earlier observations, in particular of the dust morphology. ) operated by the NAOJ.

  1. Starr-Edwards valves at the aortic and mitral positions implanted for 39 years.

    PubMed

    Misawa, Shun-ichi; Aizawa, Kei; Kaminishi, Yuichiro; Muraoka, Arata; Misawa, Yoshio

    2011-06-01

    Cloth-covered Starr-Edwards caged ball valves implanted in the aortic and mitral valve positions for 39 years were extracted. Both showed valve dysfunction resulting from pannus overgrowth. The metal cages of the Starr-Edwards valves were covered with worn cloth. This case indicates the extended durability of Starr-Edwards valves and the importance of the design and materials of prosthetic heart valves to avoid pannus overgrowth and prosthetic valve abrasion.

  2. First-Ever Census of Variable Mira-Type Stars in Galaxy Outside the Local Group

    NASA Astrophysics Data System (ADS)

    2003-05-01

    First-Ever Census of Variable Mira-Type Stars in Galaxy Outsidethe Local Group Summary An international team led by ESO astronomer Marina Rejkuba [1] has discovered more than 1000 luminous red variable stars in the nearby elliptical galaxy Centaurus A (NGC 5128) . Brightness changes and periods of these stars were measured accurately and reveal that they are mostly cool long-period variable stars of the so-called "Mira-type" . The observed variability is caused by stellar pulsation. This is the first time a detailed census of variable stars has been accomplished for a galaxy outside the Local Group of Galaxies (of which the Milky Way galaxy in which we live is a member). It also opens an entirely new window towards the detailed study of stellar content and evolution of giant elliptical galaxies . These massive objects are presumed to play a major role in the gravitational assembly of galaxy clusters in the Universe (especially during the early phases). This unprecedented research project is based on near-infrared observations obtained over more than three years with the ISAAC multi-mode instrument at the 8.2-m VLT ANTU telescope at the ESO Paranal Observatory . PR Photo 14a/03 : Colour image of the peculiar galaxy Centaurus A . PR Photo 14b/03 : Location of the fields in Centaurus A, now studied. PR Photo 14c/03 : "Field 1" in Centaurus A (visual light; FORS1). PR Photo 14d/03 : "Field 2" in Centaurus A (visual light; FORS1). PR Photo 14e/03 : "Field 1" in Centaurus A (near-infrared; ISAAC). PR Photo 14f/03 : "Field 2" in Centaurus A (near-infrared; ISAAC). PR Photo 14g/03 : Light variation of six variable stars in Centaurus A PR Photo 14h/03 : Light variation of stars in Centaurus A (Animated GIF) PR Photo 14i/03 : Light curves of four variable stars in Centaurus A. Mira-type variable stars Among the stars that are visible in the sky to the unaided eye, roughly one out of three hundred (0.3%) displays brightness variations and is referred to by astronomers as a

  3. A very rare entity of diabetes insipidus associated with Edwards syndrome.

    PubMed

    Demir, Nihat; Doğan, Murat; Peker, Erdal; Bulan, Keziban; Tuncer, Oğuz

    2013-08-01

    Edwards syndrome is the second most commonly seen trisomy. It was first described by John Hamilton Edwards in 1960. Although most cases result in termination or foetal loss, live births have been documented in 5%. Edwards syndrome is characterized by multisystem anomalies, of which holoprosencephaly (HPE) is observed in 4-8% of cases. The clinical findings correspond to the degree of HPE malformation. Convulsions and endocrinopathies are among the severe clinical findings. The most common endocrinopathies are central diabetes insipidus (DI), hypothyroidism, hypocortisolism and growth hormone deficiency. The coexistence of holoproencephaly and DI in Edwards syndrome was discussed under the light of literature.

  4. John Goodricke, Edward Pigott, and Their Study of Variable Stars

    NASA Astrophysics Data System (ADS)

    French, Linda M.

    2011-05-01

    John Goodricke (1764-1786) and Edward Pigott (1753-1825) are credited with determining the first accurate periods for several important variable stars. Goodricke's name is associated with the determination of the period of the eclipsing binary Algol (Beta Persei); for this he was awarded the Copley Prize of the Royal Society of London. He also determined the periods of the contact binary Beta Lyrae and of Delta Cephei, the prototype Cepheid variable. Around the same time, Edward Pigott obtained the period of Eta Aquilae, another Cepheid. In actuality, the two collaborated on all these observations; today we would call them co-discoverers. Goodricke is the better known of the two, in part because he won the Copley Medal, in part because of his tragically short life, and in part because he was deaf. Edward Pigott was the more experienced observer, having worked with his father Nathaniel on determining the longitudes of several cities on the Continent. Evidence shows, however, that Goodricke had some astronomical experience while a student at the Warrington Academy. The journals of the two show that they developed a partnership that made the most of both their talents over the brief time (less than five years) they worked together before Goodricke's death. Today, the two are remembered as having suggested eclipses as the cause for the periodic dimming of Algol. This explanation is accepted today as the correct one. In their day, however, most eminent astronomers believed that starspots were a more likely cause for the dimming. By the time of John Goodricke's death, he seems to have accepted that explanation as well. A study of the work of Goodricke and Pigott contains many lessons for today's observers of variable stars. This work was supported by an AAS Small Research Grant and by the Pollack Award of the Dudley Observatory.

  5. Minimum flow unit installation at the South Edwards Hydro Plant

    SciTech Connect

    Bernhardt, P.; Bates, D.

    1995-12-31

    Niagara Mohawk Power Corp. owns and operates the 3.3 MW South Edwards Hydro Plant in Northern New York. The FERC license for this plant requires a minimum flow release in the bypass region of the river. NMPC submitted a license amendment to the FERC to permit the addition of a minimum flow unit to take advantage of this flow. The amendment was accepted, permitting the installation of the 236 kw, 60 cfs unit to proceed. The unit was installed and commissioned in 1994.

  6. Salutary swan song for the Starr Edwards valve.

    PubMed

    Masilonyane-Jones, Taolo Vijay; Blackham, Ruth; Alvarez, John

    2010-07-01

    The Starr-Edwards valve was the first manufactured valve to be used successfully as a cardiac valve replacement in 1960. Although superseded by newer valves over the decades it has achieved an excellent track record. It has unique features, namely a protective metal casing around the ball poppet and a large and thick sewing ring. We describe the last implant of this valve in Australia; it has now been withdrawn by the manufacturer. In this particular case, the unique features of this valve made the required surgery quite simple and avoided the need for complex mitral valve surgery in a very high-risk patient.

  7. John Goodricke, Edward Pigott, and Their Study of Variable Stars

    NASA Astrophysics Data System (ADS)

    French, Linda M.

    2012-06-01

    John Goodricke and Edward Pigott, working in York, England, between 1781 and 1786, determined the periods of variation of eclipsing binaries such as Algol and Beta Lyrae and speculated that the eclipses of Algol might be caused by a "dark body," perhaps even a planet. They also determined the periods of variation of the first two known Cepheid variables, the stars whose period-luminosity relation today enables astronomers to determine distances to distant galaxies. Goodricke holds special interest because he was completely deaf and because he died at the age of 21. The lives and work of these two astronomers are described.

  8. Effect of hinge gap width of a St. Jude medical bileaflet mechanical heart valve on blood damage potential--an in vitro micro particle image velocimetry study.

    PubMed

    Jun, Brian H; Saikrishnan, Neelakantan; Arjunon, Sivakkumar; Yun, B Min; Yoganathan, Ajit P

    2014-09-01

    The hinge regions of the bileaflet mechanical heart valve (BMHV) can cause blood element damage due to nonphysiological shear stress levels and regions of flow stasis. Recently, a micro particle image velocimetry (μPIV) system was developed to study whole flow fields within BMHV hinge regions with enhanced spatial resolution under steady leakage flow conditions. However, global velocity maps under pulsatile conditions are still necessary to fully understand the blood damage potential of these valves. The current study hypothesized that the hinge gap width will affect flow fields in the hinge region. Accordingly, the blood damage potential of three St. Jude Medical (SJM) BMHVs with different hinge gap widths was investigated under pulsatile flow conditions, using a μPIV system. The results demonstrated that the hinge gap width had a significant influence during the leakage flow phase in terms of washout and shear stress characteristics. During the leakage flow, the largest hinge gap generated the highest Reynolds shear stress (RSS) magnitudes (~1000 N/m²) among the three valves at the ventricular side of the hinge. At this location, all three valves indicated viscous shear stresses (VSS) greater than 30 N/m². The smallest hinge gap exhibited the lowest level of shear stress values, but had the poorest washout flow characteristics among the three valves, demonstrating propensity for flow stasis and associated activated platelet accumulation potential. The results from this study indicate that the hinge is a critical component of the BMHV design, which needs to be optimized to find the appropriate balance between reduction in fluid shear stresses and enhanced washout during leakage flow, to ensure minimal thrombotic complications. PMID:24976188

  9. Effect of hinge gap width of a St. Jude medical bileaflet mechanical heart valve on blood damage potential--an in vitro micro particle image velocimetry study.

    PubMed

    Jun, Brian H; Saikrishnan, Neelakantan; Arjunon, Sivakkumar; Yun, B Min; Yoganathan, Ajit P

    2014-09-01

    The hinge regions of the bileaflet mechanical heart valve (BMHV) can cause blood element damage due to nonphysiological shear stress levels and regions of flow stasis. Recently, a micro particle image velocimetry (μPIV) system was developed to study whole flow fields within BMHV hinge regions with enhanced spatial resolution under steady leakage flow conditions. However, global velocity maps under pulsatile conditions are still necessary to fully understand the blood damage potential of these valves. The current study hypothesized that the hinge gap width will affect flow fields in the hinge region. Accordingly, the blood damage potential of three St. Jude Medical (SJM) BMHVs with different hinge gap widths was investigated under pulsatile flow conditions, using a μPIV system. The results demonstrated that the hinge gap width had a significant influence during the leakage flow phase in terms of washout and shear stress characteristics. During the leakage flow, the largest hinge gap generated the highest Reynolds shear stress (RSS) magnitudes (~1000 N/m²) among the three valves at the ventricular side of the hinge. At this location, all three valves indicated viscous shear stresses (VSS) greater than 30 N/m². The smallest hinge gap exhibited the lowest level of shear stress values, but had the poorest washout flow characteristics among the three valves, demonstrating propensity for flow stasis and associated activated platelet accumulation potential. The results from this study indicate that the hinge is a critical component of the BMHV design, which needs to be optimized to find the appropriate balance between reduction in fluid shear stresses and enhanced washout during leakage flow, to ensure minimal thrombotic complications.

  10. Time variation observations of ISO SWS spectra of two oxygen-rich Mira variables

    NASA Astrophysics Data System (ADS)

    Onaka, T.; de Jong, T.; Yamamura, I.; Cami, J.; Tanab'e, T.

    1999-03-01

    Two M-type Mira variables, Z Cyg and T Cep, have been observed with SWS01 over an entire light variability cycle. Each star was observed 7 times with an interval of variability phase of approximately 0.2. Z Cyg has prominent ``silicate bands'' at 10 and 20 μm and shows large variation in the circumstellar emission. The 10 and 20 μm bands become stronger relative to the photospheric emission at maximum than at minimum and the relative intensity of the 10 μm to the 20 μm bands increases at maximum, indicating increase in the temperature of circumstellar grains. In contrast, T Cep shows relatively small, but complicated variation in its SWS spectrum. The dust shell emission is weak in T Cep compared to Z Cyg. It has atypical 10 μm feature, peaking at λ > 10 μm and band emission around 13 μm. It also shows several molecular features, including 13-17 μm CO2 and 7.3 μm SO2 bands, both of which originate from the layers of temperature of less than 1000 K. These circumstellar molecular bands show significant variations. On the other hand, the continuum slope of the dust emission in T Cep shows little change, indicating that the dust temperature does not vary largely during light variation. Neither the circumstellar molecular features nor the dust continuum intensity seems to vary synchronously with the visual light variation. The amounts of SO2 molecules and dust grains seem to be decreasing after the maximum.

  11. VizieR Online Data Catalog: A study of dust nucleation in Mira. Part I. (Kaminski+, 2016)

    NASA Astrophysics Data System (ADS)

    Kaminski, T.; Wong, K. T.; Schmidt, M. R.; Muller, H. S. P.; Gottlieb, C. A.; Cherchneff, I.; Menten, K. M.; Keller, D.; Brunken, S.; Winters, J. M.; Patel, N. A.

    2016-07-01

    Files contain ALMA observations of AlO emission in Mira (omicron Ceti) in two rotational transitions, N=6-5 and 9-8, and obtained at different epochs. Spectral cubes, moment-zero maps, and spectra of the entire emission source are provided and correspond directly to those presented in the paper (Figs. 2, 3, and 5). Complementary continuum data are also included in separate files. The data were self-calibrated and therefore their absolute astrometry is inaccurate. Relative spatial coordinates should be used. (2 data files).

  12. 77 FR 41953 - Representative Edward J. Markey; Filing of Food Additive Petition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... this petition, FDA is actively assessing the safety of BPA (see 75 FR 17145, April 5, 2010; see also... HUMAN SERVICES Food and Drug Administration 21 CFR Part 175 Representative Edward J. Markey; Filing of...: The Food and Drug Administration (FDA) is announcing that Representative Edward J. Markey has filed...

  13. Geologic framework and hydrogeologic characteristics of the Edwards Aquifer outcrop, Comal County, Texas

    USGS Publications Warehouse

    Small, T.A.; Hanson, J.A.

    1994-01-01

    In Comal County, the Edwards aquifer is probably most vulnerable to surface contamination in the rapidly urbanizing areas on the Edwards aquifer outcrop. Possible contamination can result from spills, leakage of hazardous materials, or runoff onto the intensely faulted and fractured, karstic limestone outcrops characteristic of the recharge zone.

  14. The Nucleus of the Planetary Nebula EGB 6 as a Post-Mira Binary

    NASA Astrophysics Data System (ADS)

    Bond, Howard E.; Ciardullo, Robin; Esplin, Taran L.; Hawley, Steven A.; Liebert, James; Munari, Ulisse

    2016-08-01

    EGB 6 is a faint, large, ancient planetary nebula (PN). Its central star, a hot DAOZ white dwarf (WD), is a prototype of a rare class of PN nuclei associated with dense, compact emission-line knots. The central star also shows excess fluxes in both the near-infrared (NIR) and mid-infrared (MIR). In a 2013 paper, we used Hubble Space Telescope (HST) images to show that the compact nebula is a point-like source, located 0.″16 (˜118 AU) from the WD. We attributed the NIR excess to an M dwarf companion star, which appeared to coincide with the dense emission knot. We now present new ground-based NIR spectroscopy, showing that the companion is actually a much cooler source with a continuous spectrum, apparently a dust-enshrouded low-luminosity star. New HST images confirm common proper motion of the emission knot and red source with the WD. The I-band, NIR, and MIR fluxes are variable, possibly on timescales as short as days. We can fit the spectral energy distribution (SED) with four blackbodies (the WD, a ˜1850 K NIR component, and MIR dust at 385 and 175 K). Alternatively, we show that the NIR/MIR SED is very similar to that of Class 0/I young stellar objects. We suggest a scenario in which the EGB 6 nucleus is descended from a wide binary similar to the Mira system, in which a portion of the wind from an AGB star was captured into an accretion disk around a companion star; a remnant of this disk has survived to the present time and is surrounded by gas photoionized by UV radiation from the WD. Based in part on data obtained with the NASA/ESA Hubble Space Telescope, obtained by the Space Telescope Science Institute. STScI is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. Also based in part on observations with the 1.5 m telescope operated by the SMARTS Consortium at Cerro Tololo Inter-American Observatory.

  15. Atlas of Light Curves of Faint Mira-Type Stars. Statistical Relations Between the Characteristics of Smoothed Phase Light Curves

    NASA Astrophysics Data System (ADS)

    Kudashkina, L. S.; Andronov, I. L.

    2010-12-01

    We propose a set of the photometric parameters which could be useful for the classiffication of the pulsating Mira-type stars and related objects and determination of the EAGB and TPAGB stages of the stellar evolution. To solve this problem, the light curves of faint Mira- type stars and of the semi-regular variable V411 Sct were approximated using the program FDCN, which computes a trigonometric polynomial of a statistically optimal degree (I.L.Andronov, 1994, 2003). The at las of statistically optimal fits of the phase curves of 34 long-period is presented, based on digitized data from the scanned "Atlas" by P. Maffei and G.Tosti (http://astro.fisica.unipg.it/atlasmaffei/main.htm). Some statistical relations between the parameters of the trigonometrical polynomial approximation of the phase curve are analyzed. for an additional criterion of detailed classiffication of long-perodic variables, we used various parameters, e.g. "period", "amplitude", "asymmetry", "slope of the ascending branch", "characteristic time of brightening by 1m": Discussion of the results is presented.

  16. Edward Meryon (1809-1880) and muscular dystrophy.

    PubMed Central

    Emery, A E; Emery, M L

    1993-01-01

    Edward Meryon was an English physician of Huguenot stock. He studied medicine at University College, London, and his chief appointments were at St Thomas's Hospital and the London Infirmary for Epilepsy and Paralysis. In a communication to the Royal Medical and Chirurgical Society in December 1851, which was published in the Transactions of the Society the following year, he described in detail eight boys in three families with a disease later to be associated with the name of Duchenne. He was particularly impressed by the predilection for males and its familial nature. He appears to have been the first physician to make a systematic study of the disorder some years before Duchenne. Images PMID:8326496

  17. Sexual portraits: Edward Melcarth and homoeroticism in modern American art.

    PubMed

    Griffey, Erin; Reay, Barry

    2012-01-01

    Although one will not find Edward Melcarth (1914-73) in the best recent histories of male homosexuality and American art, he was not always so spectral. Named in Life magazine in 1950 as one of the best young American artists, he exhibited as a painter, draftsman and sculptor and also practised as an illustrator, photographer and designer. His work survives in the Forbes Collection, in the Smithsonian Institution and in the art archives at the Kinsey Institute. We argue that Melcarth’s vision of the erotic was far broader than the traditional categories of sexuality that are perpetuated in art histories of homoeroticism in modern America – and that such a revisioning enables a reinterpretation of some of the better known images of homosexual art.

  18. A psychoanalytic study of Edward de Vere's The Tempest.

    PubMed

    Waugaman, Richard M

    2009-01-01

    There is now abundant evidence that Freud was correct in believing Edward de Vere (1550-1604) wrote under the pseudonym "William Shakespeare." One common reaction is "What difference does it make?" I address that question by examining many significant connections between de Vere's life and The Tempest. Such studies promise to bring our understanding of Shakespeare's works back into line with our usual psychoanalytic approach to literature, which examines how a great writer's imagination weaves a new creation out of the threads of his or her life experiences. One source of the intense controversy about de Vere's authorship is our idealization of the traditional author, about whom we know so little that, as Freud noted, we can imagine his personality was as fine as his works. PMID:20001197

  19. Transcatheter mitral valve implantation (TMVI) using the Edwards FORTIS device.

    PubMed

    Bapat, Vinayak; Buellesfeld, Lutz; Peterson, Mark D; Hancock, Jane; Reineke, David; Buller, Chris; Carrel, Thierry; Praz, Fabien; Rajani, Ronal; Fam, Neil; Kim, Han; Redwood, Simon; Young, Christopher; Munns, Christopher; Windecker, Stephan; Thomas, Martyn

    2014-09-01

    Transcatheter aortic valve implantation (TAVI) has demonstrated the feasibility of treating valvular heart disease with transcatheter therapy. On the back of this success, various transcatheter concepts are being evaluated to treat other valvular disease, especially mitral regurgitation (MR). The concepts currently approved to treat MR replicate surgical mitral valve repair. However, most of them cannot eliminate MR completely. Similar to TAVI, a transcatheter mitral valve implantation may provide a valuable alternative. The FORTIS transcatheter mitral valve (Edwards Lifesciences, Irvine, CA, USA) is a self-expanding device implanted via a transapical approach. We describe our experience and early results in the first five patients treated on compassionate grounds. We also describe the details of the device, selection criteria and technical details of implantation. PMID:25256325

  20. Enhanced recharge and karst, Edwards aquifer, south central Texas

    SciTech Connect

    Hammond, W.W. Jr. . Center for Water Research)

    1993-02-01

    Enhanced recharge is a water management strategy which can add significant quantities of ground water to the available water resources of the San Antonio region by utilizing the immense storage capacity of the unconfined zone of the Edwards aquifer. The Edwards aquifer presently is the sole source of water for a population of over 1,200,000, meeting public supply, industrial, and irrigation demands over a wide area of south central Texas. Valdina Farms Sinkhole is located adjacent to Seco Creek in Medina County and is in the recharge zone of the aquifer. Initial studies indicated that the sinkholes was capable of taking flood flows from Seco Creek and functioning as a recharge structure. Stream channels in the cavern system associated with Valdina Farms Sinkhole were incised into cave deposits and flood debris was present in the caverns at some distance from the sinkhole. Chemical analyses of samples of water from the cave and from nearby wells showed nitrate concentrations that decreased with distance from the cavern. Gradient of the potentiometric surface in the vicinity of the cave was very low, indicating high values of hydraulic conductivity for the aquifer. Based on evidence from these field studies a dam was constructed in 1982 on Seco Creek and a flood diversion channel was excavated to the sinkhole. Reservoir capacity is 2 acre-feet and design recharge rate is 3.8-6.7 m[sup 3]/sec. Annual recharge at the sinkhole has varied from 0 during periods of low runoff to 12,915 acre-feet.

  1. High-resolution fluid-structure interaction simulations of flow through a bi-leaflet mechanical heart valve in an anatomic aorta.

    PubMed

    Borazjani, Iman; Ge, Liang; Sotiropoulos, Fotis

    2010-02-01

    We have performed high-resolution fluid-structure interaction simulations of physiologic pulsatile flow through a bi-leaflet mechanical heart valve (BMHV) in an anatomically realistic aorta. The results are compared with numerical simulations of the flow through an identical BMHV implanted in a straight aorta. The comparisons show that although some of the salient features of the flow remain the same, the aorta geometry can have a major effect on both the flow patterns and the motion of the valve leaflets. For the studied configuration, for instance, the BMHV leaflets in the anatomic aorta open much faster and undergo a greater rebound during closing than the same valve in the straight axisymmetric aorta. Even though the characteristic triple-jet structure does emerge downstream of the leaflets for both cases, for the anatomic case the leaflet jets spread laterally and diffuse much faster than in the straight aorta due to the aortic curvature and complex shape of the anatomic sinus. Consequently the leaflet shear layers in the anatomic case remain laminar and organized for a larger portion of the accelerating phase as compared to the shear layers in the straight aorta, which begin to undergo laminar instabilities well before peak systole is reached. For both cases, however, the flow undergoes a very similar explosive transition to the small-scale, turbulent-like state just prior to reaching peak systole. The local maximum shear stress is used as a metric to characterize the mechanical environment experienced by blood cells. Pockets of high local maximum shear are found to be significantly more widespread in the anatomic aorta than in the straight aorta throughout the cardiac cycle. Pockets of high local maximum shear were located near the leaflets and in the aortic arc region. This work clearly demonstrates the importance of the aortic geometry on the flow phenomena in a BMHV and demonstrates the potential of our computational method to carry out image

  2. Hydrogeological framework of the Edwards-Trinity aquifer system, west-central Texas

    USGS Publications Warehouse

    Barker, Rene A.; Ardis, Ann F.

    1996-01-01

    The Edwards-Trinity aquifer system underlies about 42,000 square miles of west-central Texas, where mostly gently dipping Lower Cretaceous strata comprise three regional aquifers and two regional confining units. The aquifers are the Edwards Aquifer of the Balcones fault zone, the Trinity Aquifer of the Balcones fault zone and Hill County, and the Edwards-Trinity Aquifer of the Edwards Plateau and Trans-Pecos. The Navarro-Del Rio confining unit confines the downdip part of the Edwards Aquifer, and the Hammett confining unit confines the updip, basal part of the Trinity Aquifer and a small southeastern fringe of the Edwards-Trinity Aquifer. Transmissivity averages less than 10,000 feet squared per day throughout more than 90 percent of the study area as the result of widespread cementation and secondary mineral growth. However, in fractured and leached rocks in the Balcones fault zone, transmissivity averages about 750,000 feet squared per day in the Edwards aquifer, which occupies less than 10 percent of the area.

  3. Geologic framework and hydrogeologic characteristics of the Edwards Aquifer outcrop, Medina County, Texas

    USGS Publications Warehouse

    Small, Ted A.; Clark, Allan K.

    2000-01-01

    The hydrogeologic subdivisions of the Edwards aquifer outcrop in Medina County generally are porous and permeable. The most porous and permeable appear to be hydrogeologic subdivision VI, the Kirschberg evaporite member of the Kainer Formation; and hydrogeologic subdivision III, the leached and collapsed members, undivided, of the Person Formation. The most porous and permeable rocks of the Devils River Formation in Medina County appear to be in the top layer. The upper member of the Glen Rose Limestone, the lower confining unit, has much less porosity and permeability than that observed in the Edwards aquifer.The Edwards aquifer has relatively large porosity and permeability resulting, in part, from the development or redistribution of secondary porosity. Lithology, stratigraphy, diagenesis, and karstification account for the effective porosity and permeability in the Edwards aquifer outcrop. Karst features that can greatly enhance effective porosity and permeability in the Edwards aquifer outcrop include sinkholes, dolines, and caves. The Edwards aquifer rocks in Medina County change from the eight-member Edwards Group to the essentially indivisible Devils River Formation. The facies change occurs along a line extending northwestward from just south of Medina Lake.

  4. A Follow-up Study of the Graduates of MiraCosta Adult High School Diploma Program 1982, 1983, 1984, 1985.

    ERIC Educational Resources Information Center

    Pereira, Cecelia

    Selected characteristics and conditions of MiraCosta Adult High School Diploma Program graduates were investigated. Data were gathered from 129 respondents by a 35-item mailed questionnaire. Questions pertained to graduates' current status, analysis of their high school experience, and recommendations for improving the adult high school diploma…

  5. Prince Edward Island Heart Health Dissemination Research Project: establishing a sustainable community mobilization initiative.

    PubMed

    White, R; Mitchell, T; Gyorfi-Dyke, E; Sweet, L; Hebert, R; Moase, O; MacPhee, R; MacDonald, B

    2001-01-01

    This paper provides an overview of the Prince Edward Island Heart Health Program (PEIHHP) Dissemination Research Project. Prince Edward Island (PEI) is a small province in the Atlantic region of Canada with a population of 137,980. The Island's economy is dependent on the fishery, agriculture, and tourism industries. Although unemployment rates are high (14.4%), Prince Edward Island has the lowest poverty rate in the country at 15.2%, high levels of social support (86%), and the second lowest rate of high chronic stress (Report on the Health of Canadians, 1996, 1999).

  6. STS-49 Landing at Edwards with First Drag Chute Landing

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Space Shuttle Endeavour concludes mission STS-49 at NASA's Ames-Dryden Flight Research Facility (later redesignated Dryden Flight Research Center), Edwards, California, with a 1:57 p.m. (PDT) landing May 16 on Edward's concrete runway 22. The planned 7-day mission, which began with a launch from Kennedy Space Center, Florida, at 4:41 p.m. (PFT), 7 May, was extended two days to allow extra time to rescue the Intelsat VI satellite and complete Space Station assembly techniques originally planned. After a perfect rendezvous in orbit and numerous attempts to grab the satellite, space walking astronauts Pierre Thuot, Rick Hieb and Tom Akers successfully rescued it by hand on the third space walk with the support of mission specialists Kathy Thornton and Bruce Melnick. The three astronauts, on a record space walk, took hold of the satellite and directed it to the shuttle where a booster motor was attached to launch it to its proper orbit. Commander Dan Brandenstein and Pilot Kevin Chilton brought Endeavours's record setting maiden voyage to a perfect landing at Edwards with the first deployment of a drag chute on a shuttle mission. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their

  7. STS-49 Landing at Edwards with First Drag Chute Landing

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Space Shuttle Endeavour concludes mission STS-49 at NASA's Ames-Dryden Flight Research Facility (later redesignated Dryden Flight Research Center), Edwards, California, with a 1:57 p.m. (PDT) landing 16 May on Edward's concrete runway 22. The planned 7-day mission, which began with a launch from Kennedy Space Center, Florida, at 4:41 p.m. (PFT), 7 May, was extended two days to allow extra time to rescue the Intelsat VI satellite and complete Space Station assembly techniques originally planned. After a perfect rendezvous in orbit and numerous attempts to grab the satellite, space walking astronauts Pierre Thuot, Rick Hieb and Tom Akers successfully rescued it by hand on the third space walk with the support of mission specialists Kathy Thornton and Bruce Melnick. The three astronauts, on a record space walk, took hold of the satellite and directed it to the shuttle where a booster motor was attached to launch it to its proper orbit. Commander Dan Brandenstein and Pilot Kevin Chilton brought Endeavours's record setting maiden voyage to a perfect landing at Edwards AFB with the first deployment of a drag chute on a shuttle mission. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their

  8. Postoperative Migration of an Edwards-SAPIEN XT Mitral Valve-in-Valve Treated With Direct Vision Implantation During Beating-Heart Bypass.

    PubMed

    Mick, Stephanie L; Roselli, Eric E; Kapadia, Samir; Tuzcu, E Murat; Krishnaswamy, Amar; Svensson, Lars G

    2016-03-01

    Transcatheter valve-in-valve mitral valve replacement provides treatment options to high-risk patients but is subject to its own complications. We present the migration of a transcatheter balloon-expandable Edwards-SAPIEN XT valve (Edwards Lifesciences, Irvine, CA) within a previously implanted surgical Carpentier-Edwards valve (Edwards Lifesciences) and our novel approach to its treatment. PMID:26897205

  9. Validation of the SMOS-MIRAS Soil Moisture Product (SML2UDP) in the Pampean Region of Argentina

    NASA Astrophysics Data System (ADS)

    Niclòs, Raquel; Rivas, Raúl; Sánchez, Juan Manuel; García-Santos, Vicente; Doña, Carolina; Valor, Enric; Holzman, Mauro; Bayala, Martín Ignacio; Carmona, Facundo; Ocampo, Dora; Soldano, Alvaro; Thibeault, Marc

    2014-05-01

    A validation campaign was carried out to evaluate the SMOS-MIRAS Soil Moisture (SM) SML2UDP product (v5.51) in the Pampean Region of Argentina on February 2013. The study area was selected because it is a vast area of flatlands containing quite homogeneous rainfed croplands, with prevalence of soybean crops, considered SMOS nominal land uses (i.e., crops with vegetation heights not exceeding 1 to 2 m by opposition to trees). Transects of ground SM measurements were collected by Delta-T ThetaProbe ML2x SM probes within four ISEA-4H9 DGG SMOS nodes. The SM data obtained by each probe transect in each parcel were checked by collecting soil samples in the same parcels at the same time and measuring their masses. The gravimetric method was used to obtain reference values. An uncertainty of ± 0.03 m3m-3 was obtained for the ML2x probes. Additionally, they were calibrated in the laboratory for different SMs by saturating and drying a specific and representative variety of soil samples collected from the experimental parcels (loam, clay loam and silt loam samples). This calibration showed again accurate operations for the ML2x probes, which even attain uncertainties of ±0.01 m3m-3, in agreement with the manufacturer. The comparison of the SM transect data collected during the campaign with the SMOS-MIRAS SML2UDP product values showed a negative bias between concurrent SMOS data and ground SM measurements, which means a slight SMOS-MIRAS underestimation, and a standard deviation of ± 0.06 m3m-3. The validation sites were selected taking as reference the locations of permanent SM stations property of the Argentinean Comisión Nacional de Actividades Espaciales (CONAE, National Commission of Space Activities), Instituto Nacional de Tecnología Agropecuaria (INTA, National Institute of Farming Technology) and Instituto de Hidrología de Llanuras (IHLLA, Plain Hydrology Institute). During the campaign several transects were carried out in the parcels where permanent SM

  10. Durability, reliability, viability: 48 year-survival of a Starr-Edwards mitral valve.

    PubMed

    Ayub, Bilal; Guthier, Justin; Wu, James K; Martinez, Matthew W

    2014-01-01

    We report a case of 67 year-old female with a 48-year survival of a Starr-Edwards valve at mitral position. The patient underwent Starr-Edwards mitral valve replacement at age of 19 years for mitral stenosis secondary to severe rheumatic valve disease. The patient had experienced a progressive decline in her functional status with increasing dyspnoea on exertion over a two-week period to eventual development of severe shortness of breath at rest prior to hospitalisation. Transoesophageal echocardiogram revealed severe para-prosthetic and intravalvular mitral valve regurgitation. The patient underwent explantation of Starr-Edwards valve and replacement with a mechanical prosthesis. Our case details the longest reported survival of a Starr-Edwards prosthetic valve at mitral area.

  11. [The Starr-Edwards heart valve: one of the oldest mechanical heart valves still functioning today].

    PubMed

    Schoenaker, Michiel H; van Wetten, Herbert B; Morshuis, Wim J

    2015-01-01

    In the 1960s, the Starr-Edwards valve was the first artificial heart valve to be successfully implanted in humans. This valve has now been in use for decades with outstanding results: patients whose life expectancy had previously been short acquired a good prognosis with this development. Nowadays the Starr-Edwards valve is not used anymore, but patients are being described today in whom these valves are still functioning well after more than 40 years.

  12. A Starr-Edwards mitral prosthesis after 44 years of good performance.

    PubMed

    De Santo, Luca Salvatore; De Feo, Marisa; Della Corte, Alessandro; Cerasuolo, Flavio; Santé, Pasquale; Torella, Michele; Nappi, Gianantonio

    2010-06-01

    The Starr-Edwards caged-ball prosthesis has been widely used to replace cardiac valves. The Model 6120 mitral prosthesis was introduced on the market in 1965 to reduce the high incidence of ball variance and thromboembolism of the previous model. We report the case of a Starr-Edwards Model 6120 which had been in place for 44 years and was still well functioning with no apparent structural damage.

  13. The phonocardiogram in a partially detached mitral (Starr-Edwards) prosthesis

    PubMed Central

    Raj, M. V. Jeeva; Clarke, C. R. A.; Fleming, H. A.

    1975-01-01

    Phonocardiographic evidence of extreme variability of the time interval between the aortic sound (A2) and the opening click (OC) with intermittent absence of the OC of a partially detached mitral prosthesis of the Starr-Edwards type has not hitherto been reported. This case illustrates the diagnostic use of phonocardiography in a malfunctioning mitral Starr-Edwards prosthesis. ImagesFig. 1Fig. 2 PMID:1197179

  14. Edward Burne-Jones' Heavenly Conception: A Biblical Cosmos

    NASA Astrophysics Data System (ADS)

    Cheney, L. D. G.

    2016-01-01

    Edward Burne-Jones was a Pre-Raphaelite artist and designer, who collaborated with William Morris on many decorative arts (stained glass windows, book illustrations, ceramic and tapestry designs). He was a founding partner in the firm Morris, Marshall, Faulkner & Company. Burne-Jones composed The Days of Creation between 1870 and 1876 for the Morris firm. These paintings were executed in gouache and gold paint, and cartoons were made for tile and in stained glass, for the Church of St. Editha at Tamworth in Staffordshire. Burne-Jones' creation was highly praised and elegantly described by Oscar Wilde: “The picture is divided into six compartments, each representing a day in the Creation of the World, under the symbol of an angel holding a crystal globe, within which is shown the work of a day.” This paper will examine how Burne-Jones visualized an unusual celestial creation where angels holding magical spheres unveil the divine manifestation for the creation of a terrestrial realm. He created a cosmic utopia of the natural world.

  15. Water Resources Investigations at Edwards Air Force Base since 1988

    USGS Publications Warehouse

    Sneed, Michelle; Nishikawa, Tracy; Martin, Peter

    2006-01-01

    Edwards Air Force Base (EAFB) in southern California (fig. 1) has relied on ground water to meet its water-supply needs. The extraction of ground water has led to two major problems that can directly affect the mission of EAFB: declining water levels (more than 120 ft since the 1920s) and land subsidence, a gradual downward movement of the land surface (more than 4 ft since the late 1920s). As water levels decline, this valuable resource becomes depleted, thus requiring mitigating measures. Land subsidence has caused cracked (fissured) runways and accelerated erosion on Rogers lakebed. In 1988, the U.S. Geological Survey (USGS), in cooperation with the U.S. Air Force, began investigations of the effects of declining water levels and land subsidence at EAFB and possible mitigation measures, such as the injection of imported surface water into the ground-water system. The cooperative investigations included data collection and analyses, numerical simulations of ground-water flow and land subsidence, and development of a preliminary simulation-optimization model. The results of these investigations indicate that the injection of imported water may help to control land subsidence; however, the potential ground-water-quality impacts are unknown.

  16. When Cri du chat syndrome meets Edwards syndrome.

    PubMed

    Xie, Yingjun; Zhou, Yi; Wu, Jianzhu; Sun, Yunxia; Chen, Yongzhen; Chen, Baojiang

    2015-03-01

    It has been well established that the 5p deletion causes Cri du chat syndrome, typically characterized by a cat‑like cry, and that duplication of 18q causes Edwards syndrome; the two are rare genetic abnormalities that separately lead to physical and mental impairments. However, the severity of the clinicopathological characteristics that arise when these two aberrations occur in one patient is unknown. Here, the first case in our knowledge of a single patient (a two‑year‑old female) with 5p partial monosomy and 18q partial trisomy is described. In the present study, chromosome microarray analysis was performed, which identified the imbalance of chromosomes 5 and 18 in the patient. The chromosome aberrations were further confirmed by fluorescence in situ hybridization. By comparing the phenotypes of combined case with those of the individual syndromes, severe clinical phenotypes of the 5p (5p15.33‑p13.3) deletion were confirmed, however, the net effect of the duplication of 18q22.3‑q23 was not determined, as this duplication only appeared to have a weak effect on the patient's phenotypes. The correlation between these chromosomal aberrations and their clinical features has implications for the identification of critical regions of 5p and 18q, particularly for the functional mapping of chromosome 18. PMID:25385231

  17. Edward (Ed) T. Schneider preparing for an F-104 flight

    NASA Technical Reports Server (NTRS)

    1989-01-01

    NASA research pilot Edward T. Scheider is shown standing in the cockpit of a two-seat F-104. He is wearing a full pressure suit, which is required on all flights above 50,000 feet. Ed served in the U.S. Navy from 1968 to 1983. He attended the U.S. Naval Test Pilot School and graduated in 1973. He was then assigned as an engineering test pilot, and as an instructor at the Naval Test Pilot School. He first arrived at what was then called the Ames-Dryden Flight Research Facility (now the Dryden Flight Research Center) as a Navy Liaison Officer on July 5, 1982. He joined NASA as a research pilot a year later. Ed was a project pilot on the F-18 High Angle-of-Attack program, the F-15 aeronautical research aircraft, the B-52 launch aircraft, and the NASA-operated SR-71 Blackbirds. Ed retired as a NASA research pilot in September 2000.

  18. Obituary: Edward W. Burke, Jr. (1924-2011)

    NASA Astrophysics Data System (ADS)

    Bloomer, Raymond, Jr.

    2011-12-01

    Dr. Edward W. Burke Jr. passed away on June 15, 2011, after suffering a heart attack. Dr. Burke devoted his professional life to the research and teaching of physics and astronomy at King College in Bristol, Tennessee. Edward W. Burke, Jr., was born in Macon, Georgia, on September 16, 1924. He was a Navy veteran, having been commissioned as an ensign in 1944. He served in the Pacific near the end of World War II. He proceeded to complete his undergraduate degree in mathematics from Presbyterian College in 1947 and pursued the M.S. and Ph.D. in physics (1949 and 1954, respectively) at the University of Wisconsin. Under the direction of Professor Julian Mack, his thesis was titled "Isotope Shift in the Spectra of Boron." Although he did research in atomic spectra in the early part of his career, his interest in astronomy and variable stars in particular were his primary interests during his long academic career. Dr. Burke began his illustrious career at King College in 1949. He initiated the astronomy program there in 1950, included constructing a 12.5 inch Newtonian telescope, homemade as was most everything in those days. Many of his students learned about photometry at the Burke Observatory on the college campus. Burke was known for his trips to the Kitt Peak and Lowell observatories accompanied by undergraduate students on his trips, all of which were made by automobile which he preferred over flying. His initial interest in Ap stars later broadened into variable and especially eclipsing binary stars. His motivation was maintained by his desire to have his students experience basic research and to spark their interest in advanced degrees. Numerous students achieved advanced science and medical degrees because of Burke's encouragement and mentoring. In 1959, Dr. Burke was awarded a Fulbright professorship and traveled to Chile where he taught physics for a year in the Engineering School at the University of Chile in Santiago. He worked to establish a physics

  19. W. Edwards Deming, quality analysis, and total behavior management

    PubMed Central

    Saunders, Richard R.; Saunders, Jay L.

    1994-01-01

    During the past 10 years, the inclusion of the word “quality” in descriptions of production methods, management approaches, educational systems, service system changes, and so forth, has grown exponentially. It appears that no new approach to any problem is likely to be given much consideration today without overt acknowledgment that some improvement in quality must be the outcome. The origins of the importance of quality are primarily rooted in the awakening recognition of the influence of W. Edwards Deming in the post-World War II restoration of Japanese industry. We provide a brief overview of Deming's approach to modernizing management methods and discuss recent criticisms from the field of organizational behavior management that his approach lacks emphasis on the role of reinforcement. We offer a different analysis of Deming's approach and relate its evolution to the contingencies of reinforcement for the behavior of consulting. We also provide an example of problem solving with Deming's approach in a social service setting familiar to many behavior analysts. PMID:22478176

  20. Recharge zone of the Edwards aquifer hydrologically associated with Barton springs in the Austin area, Texas

    USGS Publications Warehouse

    Slagle, Diana L.; Ardis, Ann F.; Slade, Raymond M.

    1986-01-01

    The Edwards aquifer extends in a narrow belt from Bell County in the northeast to Kinney County in the southwest (index map) and provides water for at least nine counties in south-central Texas. Hydrologic boundaries divide the Edwards aquifer in the Austin area for which Barton Springs is the major discharge point. This part of the Edwards aquifer provides the municipal, industrial, domestic, and agricultural water supplies for about 30,000 people in the Austin area (southern Travis and northern Hays counties). Discharge from Barton Springs sustains streamflow at the mouth of Barton Creek and flows into Town Lake. Much of the land use within the outcrop area of the Edwards aquifer near Austin is rapidly changing from natural woodland and grassland to commercial and residential developments. Because urban development can result in a substantial degradation of the quality of water that recharges the aquifer, the extent of the recharge zone of the Edwards aquifer was delineated to provide information to the City of Austin for their use in formulating a plan for protecting and managing groundwater quality. The purpose of this report is to define and delineate the areal extent of the recharge zone of the Edwards aquifer in southern Travis and northern Hays Counties. The areal boundary of the recharge zone was determined by: (1) geologic mapping of the aquifer area; (2) interpretation of aerial photographs; (3) field verification of existing geologic maps; and (4) streamflow-loss studies. 

  1. Geologic framework and hydrogeologic characteristics of the Edwards Aquifer outcrop, Hays County, Texas

    USGS Publications Warehouse

    Hanson, John A.; Small, Ted A.

    1995-01-01

    All of the hydrogeologic subdivisions within the Edwards aquifer outcrop in Hays County have some porosity and permeability. The most porous and permeable appear to be hydrogeologic subdivision VI, the Kirschberg evaporite member of the Kainer Formation; hydrogeologic subdivision III, the leached and collapsed members, undivided; and hydrogeologic subdivision II, the cyclic and marine members, undivided, of the Person Formation. The two types of porosity in the Edwards aquifer outcrop are fabric selective, which is related to depositional or diagenetic elements and typically exists in specific stratigraphic horizons; and not fabric selective, which can exist in any lithostratigraphic horizon. Permeability, the capacity of porous rock to transmit water, depends on the physical properties of the rock such as size, shape, and distribution of pores, and fissuring and dissolution. Two faults, San Marcos Springs and Mustang Branch, completely, or almost completely, offset the Edwards aquifer by juxtaposing Edwards aquifer limestone against nearly impermeable upper confining units along parts of their traces across Hays County. These faults are thought to be barriers, or partial barriers, to groundwater flow where the beds are juxtaposed. In Hays County, the Edwards aquifer probably is most vulnerable to surface contamination in the rapidly urbanizing areas on the Edwards aquifer outcrop. Contamination can result from spills or leakage of hazardous materials; or runoff on the intensely faulted and fractured, karstic limestone outcrops characteristic of the recharge zone.

  2. Short-term hemodynamic performance of the mitral Carpentier-Edwards PERIMOUNT pericardial valve. Carpentier-Edwards PERIMOUNT Investigators

    NASA Technical Reports Server (NTRS)

    Firstenberg, M. S.; Morehead, A. J.; Thomas, J. D.; Smedira, N. G.; Cosgrove, D. M. 3rd; Marchand, M. A.

    2001-01-01

    BACKGROUND: Although long-term durability data exist, little data are available concerning the hemodynamic performance of the Carpentier-Edwards PERIMOUNT pericardial valve in the mitral position. METHODS: Sixty-nine patients who were implanted with mitral PERIMOUNT valves at seven international centers between January 1996 and February 1997 consented to participate in a short-term echocardiography follow-up. Echocardiographs were collected at a mean of 600+/-133 days after implantation (range, 110 to 889 days); all underwent blinded core lab analysis. RESULTS: At follow-up, peak gradients were 9.09+/-3.43 mm Hg (mean, 4.36+/-1.79 mm Hg) and varied inversely with valve size (p < 0.05). The effective orifice areas were 2.5+/-0.6 cm2 and tended to increase with valve size (p = 0.08). Trace mitral regurgitation (MR) was common (n = 48), 9 patients had mild MR, 1 had moderate MR, none had severe MR. All MR was central (n = 55) or indeterminate (n = 3). No paravalvular leaks were observed. Mitral regurgitation flow areas were 3.4+/-2.8 cm2 and were without significant volumes. CONCLUSIONS: In this multicenter study, these mitral valves are associated with trace, although physiologically insignificant, central MR. Despite known echocardiographic limitations, the PERIMOUNT mitral valves exhibit similar hemodynamics to other prosthetic valves.

  3. Conceptualization and simulation of the Edwards aquifer, San Antonio region, Texas

    USGS Publications Warehouse

    Lindgren, K.J.; Dutton, A.R.; Hovorka, S.D.; Worthington, S.R.H.; Painter, S.; ,

    2005-01-01

    Numerical ground-water flow models for the Edwards aquifer in the San Antonio region of Texas generally have been based on a diffuse-flow conceptualization. That is, although conduits likely are present, the assumption is that flow in the aquifer predominantly is through a network of small fractures and openings sufficiently numerous that the aquifer can be considered a porous-media continuum at the regional scale. Whether flow through large fractures and conduits or diffuse flow predominates in the Edwards aquifer at the regional scale is an open question. A new numerical ground-water-flow model (Edwards aquifer model) that incorporates important components of the latest information and an alternate conceptualization of the Edwards aquifer was developed. The conceptualization upon which the Edwards aquifer model is based emphasizes conduit development and conduit flow, and the model can be considered a test of one of two reasonable conceptualizations. The model incorporates conduits simulated as generally continuously connected, one-cell-wide (1,320 feet) zones with very large hydraulic-conductivity values (as much as 300,000 feet per day). The locations of the conduits are based on a number of factors, including major potentiometric-surface troughs in the aquifer, the presence of sinking streams, geochemical information, and geologic structures (for example, faults and grabens). The model includes both the San Antonio and Barton Springs segments of the Edwards aquifer in the San Antonio region, Texas, and was calibrated for steady-state (1939-46) and transient (1947-2000) conditions. Transient simulations were conducted using monthly recharge and pumpage (withdrawals) data. The predominantly conduit-flow conceptualization incorporated in the Edwards aquifer model yielded a reasonably good match between measured and simulated hydraulic heads in the confined part of the aquifer and between measured and simulated springflows. The simulated directions of flow in the

  4. Dryden B-52 Launch Aircraft on Edwards AFB Runway

    NASA Technical Reports Server (NTRS)

    1996-01-01

    NASA's venerable workhorse, the B-52 mothership, rolls out on the Edwards AFB runway after a test flight in 1996. Over the course of more than 40 years, the B-52 launched numerous experimental aircraft, ranging from the X-15 to the X-38, and was also used as a flying testbed for a variety of other research projects. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket

  5. X-31 in Banked Flight over Edwards AFB

    NASA Technical Reports Server (NTRS)

    1994-01-01

    One of two X-31 Enhanced Fighter Maneuverability Demonstrator aircraft, flown by an international test organization at NASA's Dryden Flight Research Center, Edwards, California, turns tightly over the desert floor on a research flight. The aircraft obtained data that may apply to the design and development of highly-maneuverable aircraft of the future. The X-31 had a three-axis thrust-vectoring system, coupled with advanced flight controls, to allow it to maneuver tightly at very high angles of attack. The X-31 Enhanced Fighter Maneuverability (EFM) demonstrator flew at the Ames- Dryden Flight Research Facility, Edwards, California (redesignated the Dryden Flight Research Center in 1994) from February 1992 until 1995 and before that at the Air Force's Plant 42 in Palmdale, California. The goal of the project was to provide design information for the next generation of highly maneuverable fighter aircraft. This program demonstrated the value of using thrust vectoring (directing engine exhaust flow) coupled with an advanced flight control system to provide controlled flight to very high angles of attack. The result was a significant advantage over most conventional fighters in close-in combat situations. The X-31 flight program focused on agile flight within the post-stall regime, producing technical data to give aircraft designers a better understanding of aerodynamics, effectiveness of flight controls and thrust vectoring, and airflow phenomena at high angles of attack. Stall is a condition of an airplane or an airfoil in which lift decreases and drag increases due to the separation of airflow. Thrust vectoring compensates for the loss of control through normal aerodynamic surfaces that occurs during a stall. Post-stall refers to flying beyond the normal stall angle of attack, which in the X-31 was at a 30-degree angle of attack. During Dryden flight testing, the X-31 aircraft established several milestones. On November 6, 1992, the X-31 achieved controlled flight

  6. X-31 #1 in Flight over Edwards AFB

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The first X-31 (Bu. No. 164584) flies over Edwards Air Force Base, California, in 1993. Aircraft 584 completed 292 flights during the Enhanced Fighter Maneuverability (EFM) program before being lost on January 19, 1995 when icing in the nose probe caused the flight control computer to receive bad data. German test pilot Karl-Heinz Lang ejected after the aircraft became uncontrollable. The program continued, using the second aircraft (Bu. No. 164585). The X-31 Enhanced Fighter Maneuverability (EFM) demonstrator flew at the Ames- Dryden Flight Research Facility, Edwards, California (redesignated the Dryden Flight Research Center in 1994) from February 1992 until 1995 and before that at the Air Force's Plant 42 in Palmdale, California. The goal of the project was to provide design information for the next generation of highly maneuverable fighter aircraft. This program demonstrated the value of using thrust vectoring (directing engine exhaust flow) coupled with an advanced flight control system to provide controlled flight to very high angles of attack. The result was a significant advantage over most conventional fighters in close-in combat situations. The X-31 flight program focused on agile flight within the post-stall regime, producing technical data to give aircraft designers a better understanding of aerodynamics, effectiveness of flight controls and thrust vectoring, and airflow phenomena at high angles of attack. Stall is a condition of an airplane or an airfoil in which lift decreases and drag increases due to the separation of airflow. Thrust vectoring compensates for the loss of control through normal aerodynamic surfaces that occurs during a stall. Post-stall refers to flying beyond the normal stall angle of attack, which in the X-31 was at a 30-degree angle of attack. During Dryden flight testing, the X-31 aircraft established several milestones. On November 6, 1992, the X-31 achieved controlled flight at a 70-degree angle of attack. On April 29, 1993

  7. STS-31 on Runway 22 at Edwards with Recovery Personnel

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Personnel and equipment converge on the orbiter Discovery to begin servicing the spacecraft following its landing April 29, 1990, at NASA's then Ames-Dryden Flight Research Facility, Edwards, California. Post-landing servicing by the recovery convoy is carried out after each Space Shuttle landing and includes safety checks for flammable and toxic gases escaping from systems aboard the orbiters, hooking up engine fuel purge and equipment coolant lines, and inspecting the brakes before the vehicle is towed from the runway to the shuttle facility at Dryden where it is prepared for the ferry flight back to the Kennedy Space Center in Florida. Up to 24 vehicles and scores of personnel make up the landing recovery convoys at Dryden. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain

  8. [Edward Blyth (1810-1873). Father of the Indian ornitology].

    PubMed

    Malec, Grzegorz

    2014-01-01

    Edward Blyth was born on 23 December 1810. When he was ayoung man he took an interest with the zoology which became his life's passion. As a young naturalist he was a conscientious observer of the nature and a man gifted with a superb memory. Unfortunately his career was not successful in London because of the conflict with the younger of the Gray brothers. Facing the prospect of no employment in The British Museum, Blyth decided to leave England for Calcutta where he was offered a post of a museum curator. The English naturalist spent in India the years from 1841 to 1862. During that time he greatly enriched the zoological collection of the museum and consequently the place had much more visitors. Regarding his private life he got married in 1854 to Elisabeth Mary Turner Hodges. Undoubtedly the next four year were the happiest in Blyth's life. After his wife's death Blyth's health condition deteriorated. The ongoing conflicts he kept having while the first stay in India and constant struggle to improve his financial status made him decide to return to England. Blyth left India in 1862. After coming back to his homeland he continued the naturalistic passions. Nevertheless Blyth was constantly troubled by the financial problems. Also, his health, both mental and physical, systematically deteriorated. Finally the death came on 27 December 1873, in London. Blyth tried in vain to gain the recognition and join the scientific establishment of the 19th century England. Constant lack of satisfactory income and often problems with health prevented the ornithologist to be fully devote to his passion. The aim of this article is to highlight some of the most important and interesting events of Blyth's life. Moreover, another objective is to popularise Blyth and his work since he was one of the greatest naturalists of that time.

  9. [Edward Blyth (1810-1873). Father of the Indian ornitology].

    PubMed

    Malec, Grzegorz

    2014-01-01

    Edward Blyth was born on 23 December 1810. When he was ayoung man he took an interest with the zoology which became his life's passion. As a young naturalist he was a conscientious observer of the nature and a man gifted with a superb memory. Unfortunately his career was not successful in London because of the conflict with the younger of the Gray brothers. Facing the prospect of no employment in The British Museum, Blyth decided to leave England for Calcutta where he was offered a post of a museum curator. The English naturalist spent in India the years from 1841 to 1862. During that time he greatly enriched the zoological collection of the museum and consequently the place had much more visitors. Regarding his private life he got married in 1854 to Elisabeth Mary Turner Hodges. Undoubtedly the next four year were the happiest in Blyth's life. After his wife's death Blyth's health condition deteriorated. The ongoing conflicts he kept having while the first stay in India and constant struggle to improve his financial status made him decide to return to England. Blyth left India in 1862. After coming back to his homeland he continued the naturalistic passions. Nevertheless Blyth was constantly troubled by the financial problems. Also, his health, both mental and physical, systematically deteriorated. Finally the death came on 27 December 1873, in London. Blyth tried in vain to gain the recognition and join the scientific establishment of the 19th century England. Constant lack of satisfactory income and often problems with health prevented the ornithologist to be fully devote to his passion. The aim of this article is to highlight some of the most important and interesting events of Blyth's life. Moreover, another objective is to popularise Blyth and his work since he was one of the greatest naturalists of that time. PMID:25033527

  10. Conceptualization and simulation of the Edwards Aquifer, San Antonio region, Texas

    USGS Publications Warehouse

    Lindgren, Richard J.; Dutton, A.R.; Hovorka, S.D.; Worthington, S.R.H.; Painter, Scott

    2004-01-01

    A new numerical ground-water-flow model (Edwards aquifer model) that incorporates important components of the latest information and plausible conceptualization of the Edwards aquifer was developed. The model includes both the San Antonio and Barton Springs segments of the Edwards aquifer in the San Antonio region, Texas, and was calibrated for steady-state (1939?46) and transient (1947?2000) conditions, excluding Travis County. Transient simulations were conducted using monthly recharge and pumpage (withdrawal) data. The model incorporates conduits simulated as continuously connected (other than being separated in eastern Uvalde and southwestern Medina Counties), one-cell-wide (1,320 feet) zones with very large hydraulic-conductivity values (as much as 300,000 feet per day). The locations of the conduits were based on a number of factors, including major potentiometric-surface troughs in the aquifer, the presence of sinking streams, geochemical information, and geologic structures (for example, faults and grabens). The simulated directions of flow in the Edwards aquifer model are most strongly influenced by the presence of simulated conduits and barrier faults. The simulated flow in the Edwards aquifer is influenced by the locations of the simulated conduits, which tend to facilitate flow. The simulated subregional flow directions generally are toward the nearest conduit and subsequently along the conduits from the recharge zone into the confined zone and toward the major springs. Structures simulated in the Edwards aquifer model influencing ground-water flow that tend to restrict flow are barrier faults. The influence of simulated barrier faults on flow directions is most evident in northern Medina County. A water budget is an accounting of inflow to, outflow from, and storage change in the aquifer. For the Edwards aquifer model steady-state simulation, recharge (from seepage losses from streams and infiltration of rainfall) accounts for 93.5 percent of the

  11. STS-58 Landing at Edwards with Drag Chute

    NASA Technical Reports Server (NTRS)

    1993-01-01

    A drag chute slows the space shuttle Columbia as it rolls to a perfect landing concluding NASA's longest mission at that time, STS-58, at the Ames-Dryden Flight Research Facility (later redesignated the Dryden Flight Research Center), Edwards, California, with a 8:06 a.m. (PST) touchdown 1 November 1993 on Edward's concrete runway 22. The planned 14 day mission, which began with a launch from Kennedy Space Center, Florida, at 7:53 a.m. (PDT), October 18, was the second spacelab flight dedicated to life sciences research. Seven Columbia crewmembers performed a series of experiments to gain more knowledge on how the human body adapts to the weightless environment of space. Crewmembers on this flight included: John Blaha, commander; Rick Searfoss, pilot; payload commander Rhea Seddon; mission specialists Bill MacArthur, David Wolf, and Shannon Lucid; and payload specialist Martin Fettman. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space

  12. Detection of an asymmetry in the envelope of the carbon Mira R Fornacis using VLTI/MIDI

    NASA Astrophysics Data System (ADS)

    Paladini, C.; Sacuto, S.; Klotz, D.; Ohnaka, K.; Wittkowski, M.; Nowotny, W.; Jorissen, A.; Hron, J.

    2012-08-01

    Aims: We present a study of the envelope morphology of the carbon Mira R For with VLTI/MIDI. This object is one of the few asymptotic giant branch (AGB) stars that underwent a dust-obscuration event. The cause of such events is still a matter of discussion. Several symmetric and asymmetric scenarios have been suggested in the literature. Methods: Mid-infrared interferometric observations were obtained separated by two years. The observations probe different depths of the atmosphere and cover different pulsation phases. The visibilities and the differential phases were interpreted using GEM-FIND, a tool for fitting spectrally dispersed interferometric observations with the help of wavelength-dependent geometric models. Results: We report the detection of an asymmetric structure revealed through the MIDI differential phase. This asymmetry is observed at the same baseline and position angle two years later. The observations are best simulated with a model that includes a uniform-disc plus a Gaussian envelope plus a point-source. The geometric model can reproduce both the visibilities and the differential phase signatures. Conclusions: Our MIDI data favour explanations of the R For obscuration event that are based on an asymmetric geometry. We clearly detect a photocentre shift between the star and the strongly resolved dust component. This might be caused by a dust clump or a substellar companion. However, the available observations do not allow us to distinguish between the two options. The finding has strong implications for future studies of the geometry of the envelope of AGB stars: if this is a binary, are all AGB stars that show an obscuration event binaries as well? Or are we looking at asymmetric mass-loss processes (i.e. dusty clumps) in the inner part of a carbon-rich Mira? Based on observations made with ESO telescopes at La Silla Paranal Observatory under program IDs 080.D-0231 and 084.D0361.Tables 1-3 and Figs. 1, 3 are only available in electronic form

  13. Quality of water in the Trinity and Edwards aquifers, south-central Texas, 1996-98

    USGS Publications Warehouse

    Fahlquist, Lynne; Ardis, Ann F.

    2004-01-01

    During 1996?98, the U.S. Geological Survey studied surface- and ground-water quality in south-central Texas. The ground-water components included the upper and middle zones (undifferentiated) of the Trinity aquifer in the Hill Country and the unconfined part (recharge zone) and confined part (artesian zone) of the Edwards aquifer in the Balcones fault zone of the San Antonio region. The study was supplemented by information compiled from four ground-water-quality studies done during 1996?98. Trinity aquifer waters are more mineralized and contain larger dissolved solids, sulfate, and chloride concentrations compared to Edwards aquifer waters. Greater variability in water chemistry in the Trinity aquifer likely reflects the more variable lithology of the host rock. Trace elements were widely detected, mostly at small concentrations. Median total nitrogen was larger in the Edwards aquifer than in the Trinity aquifer. Ammonia nitrogen was detected more frequently and at larger concentrations in the Trinity aquifer than in the Edwards aquifer. Although some nitrate nitrogen concentrations in the Edwards aquifer exceeded a U.S. Geological Survey national background threshold concentration, no concentrations exceeded the U.S. Environmental Protection Agency public drinking-water standard. Synthetic organic compounds, such as pesticides and volatile organic compounds, were detected in the Edwards aquifer and less frequently in the Trinity aquifer, mostly at very small concentrations (less than 1 microgram per liter). These compounds were detected most frequently in urban unconfined Edwards aquifer samples. Atrazine and its breakdown product deethylatrazine were the most frequently detected pesticides, and trihalomethanes were the most frequently detected volatile organic compounds. Widespread detections of these compounds, although at small concentrations, indicate that anthropogenic activities affect ground-water quality. Radon gas was detected throughout the Trinity

  14. Geohydrologic Framework of the Edwards and Trinity Aquifers, South-Central Texas

    USGS Publications Warehouse

    Blome, Charles D.; Faith, Jason R.; Ozuna, George B.

    2007-01-01

    This five-year USGS project, funded by the National Cooperative Geologic Mapping Program, is using multidisciplinary approaches to reveal the surface and subsurface geologic architecture of two important Texas aquifers: (1) the Edwards aquifer that extends from south of Austin to west of San Antonio and (2) the southern part of the Trinity aquifer in the Texas Hill Country west and south of Austin. The project's principal areas of research include: Geologic Mapping, Geophysical Surveys, Geochronology, Three-dimensional Modeling, and Noble Gas Geochemistry. The Edwards aquifer is one of the most productive carbonate aquifers in the United States. It also has been designated a sole source aquifer by the U.S. Environmental Protection Agency and is the primary source of water for San Antonio, America's eighth largest city. The Trinity aquifer forms the catchment area for the Edwards aquifer and it intercepts some surface flow above the Edwards recharge zone. The Trinity may also contribute to the Edwards water budget by subsurface flow across formation boundaries at considerable depths. Dissolution, karst development, and faulting and fracturing in both aquifers directly control aquifer geometry by compartmentalizing the aquifer and creating unique ground-water flow paths.

  15. Altus I aircraft landing on Edwards lakebed runway 23

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The remotely-piloted Altus I aircraft lands on Rogers Dry Lake adjacent to NASA's Dryden Flight Research Center, Edwards, Calif. The short series of test flights sponsored by the Naval Postgraduate School in early August, 1997, were designed to demonstrate the ability of the experimental craft to cruise at altitudes above 40,000 feet for sustained durations. On its final flight Aug. 15, the Altus I reached an altitude of 43,500 feet. The Altus I and its sister ship, the Altus II, are variants of the Predator surveillance drone built by General Atomics/Aeronautical Systems, Inc. They are designed for high-altitude, long-duration scientific sampling missions, and are powered by turbocharged piston engines. The Altus I incorporates a single-stage turbocharger, while the Altus II, built for NASA's Environmental Research Aircraft and Sensor Technology program, sports a two-stage turbocharger to enable the craft to fly at altitudes above 55,000 feet. The Altus II, the first of the two craft to be completed, made its first flight on May 1, 1996. With its engine augmented by a single-stage turbocharger, the Altus II reached an altitude of 37,000 ft during its first series of development flights at Dryden in Aug., 1996. In Oct. of that year, the Altus II was flown in an Atmospheric Radiation Measurement study for the Department of Energy's Sandia National Laboratory in Oklahoma. During the course of those flights, the Altus II set a single-flight endurance record for remotely-operated aircraft of more than 26 hours. The Altus I, completed in 1997, flew a series of development flights at Dryden that summer. Those test flights culminated with the craft reaching an altitude of 43,500 ft while carrying a simulated 300-lb payload, a record for an unmanned aircraft powered by a piston engine augmented with a single-stage turbocharger. The Altus II sustained an altitudeof 55,000 feet for four hours in 1999. A pilot in a control station on the ground flies the craft by radio

  16. Benefits of size dimorphism and copulatory silk wrapping in the sexually cannibalistic nursery web spider, Pisaurina mira.

    PubMed

    Anderson, Alissa G; Hebets, Eileen A

    2016-02-01

    In sexually cannibalistic animals, male fitness is influenced not only by successful mate acquisition and egg fertilization, but also by avoiding being eaten. In the cannibalistic nursery web spider, Pisaurina mira, the legs of mature males are longer in relation to their body size than those of females, and males use these legs to aid in wrapping a female's legs with silk prior to and during copulation. We hypothesized that elongated male legs and silk wrapping provide benefits to males, in part through a reduced likelihood of sexual cannibalism. To test this, we paired females of random size with males from one of two treatment groups-those capable of silk wrapping versus those incapable of silk wrapping. We found that males with relatively longer legs and larger body size were more likely to mate and were less likely to be cannibalized prior to copulation. Regardless of relative size, males capable of silk wrapping were less likely to be cannibalized during or following copulation and had more opportunities for sperm transfer (i.e. pedipalpal insertions). Our results suggest that male size and copulatory silk wrapping are sexually selected traits benefiting male reproductive success. PMID:26911340

  17. Benefits of size dimorphism and copulatory silk wrapping in the sexually cannibalistic nursery web spider, Pisaurina mira.

    PubMed

    Anderson, Alissa G; Hebets, Eileen A

    2016-02-01

    In sexually cannibalistic animals, male fitness is influenced not only by successful mate acquisition and egg fertilization, but also by avoiding being eaten. In the cannibalistic nursery web spider, Pisaurina mira, the legs of mature males are longer in relation to their body size than those of females, and males use these legs to aid in wrapping a female's legs with silk prior to and during copulation. We hypothesized that elongated male legs and silk wrapping provide benefits to males, in part through a reduced likelihood of sexual cannibalism. To test this, we paired females of random size with males from one of two treatment groups-those capable of silk wrapping versus those incapable of silk wrapping. We found that males with relatively longer legs and larger body size were more likely to mate and were less likely to be cannibalized prior to copulation. Regardless of relative size, males capable of silk wrapping were less likely to be cannibalized during or following copulation and had more opportunities for sperm transfer (i.e. pedipalpal insertions). Our results suggest that male size and copulatory silk wrapping are sexually selected traits benefiting male reproductive success.

  18. STS-36 on Edwards Runway with Recovery Personnel

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Personnel and equipment converge on the orbiter Atlantis to begin servicing the spacecraft following its landing 4 March 1990, at NASA's then Ames-Dryden Flight Research Facility, Edwards, California. Mission elapsed time for the Department of Defense mission was 4 days, 10 hours, 19 minutes and 15 seconds. Actual landing time was 10:08 a.m. Post-landing servicing by the recovery convoy is carried out after each Space Shuttle landing and includes safety checks for flammable and toxic gases escaping from systems aboard the orbiters, hooking up engine fuel purge and equipment coolant lines, and inspecting the brakes before the vehicle is towed from the runway to the shuttle facility at Dryden where it is prepared for the ferry flight back to the Kennedy Space Center in Florida. Up to 24 vehicles and scores of personnel make up the landing recovery convoys at Dryden. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed

  19. STS-31 on Runway 22 at Edwards with Recovery Personnel

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Personnel and equipment converge on the orbiter Discovery to begin servicing the spacecraft following its landing April 29, 1990, at NASA's then Ames-Dryden Flight Research Facility, Edwards, California. Post-landing servicing by the recovery convoy is carried out after each Space Shuttle landing and includes safety checks for flammable and toxic gases escaping from systems aboard the orbiters, hooking up engine fuel purge and equipment coolant lines, and inspecting the brakes before the vehicle is towed from the runway to the shuttle facility at Dryden where it is prepared for the ferry flight back to the Kennedy Space Center in Florida. Up to 24 vehicles and scores of personnel make up the landing recovery convoys at Dryden. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed to be continually reused. When Space Shuttles are used to transport complete scientific laboratories into space, the laboratories remain

  20. SR-71 Tail #844 Landing at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1996-01-01

    With distinctive heat waves trailing behind its engines, NASA Dryden Flight Research Center's SR-71A, tail number 844, lands at the Edwards AFB runway after a 1996 flight. Two SR-71 aircraft have been used by NASA as testbeds for high-speed and high-altitude aeronautical research. The aircraft, an SR-71A and an SR-71B pilot trainer aircraft, have been based here at NASA's Dryden Flight Research Center, Edwards, California. They were transferred to NASA after the U.S. Air Force program was cancelled. As research platforms, the aircraft can cruise at Mach 3 for more than one hour. For thermal experiments, this can produce heat soak temperatures of over 600 degrees Fahrenheit (F). This operating environment makes these aircraft excellent platforms to carry out research and experiments in a variety of areas -- aerodynamics, propulsion, structures, thermal protection materials, high-speed and high-temperature instrumentation, atmospheric studies, and sonic boom characterization. The SR-71 was used in a program to study ways of reducing sonic booms or over pressures that are heard on the ground, much like sharp thunderclaps, when an aircraft exceeds the speed of sound. Data from this Sonic Boom Mitigation Study could eventually lead to aircraft designs that would reduce the 'peak' overpressures of sonic booms and minimize the startling affect they produce on the ground. One of the first major experiments to be flown in the NASA SR-71 program was a laser air data collection system. It used laser light instead of air pressure to produce airspeed and attitude reference data, such as angle of attack and sideslip, which are normally obtained with small tubes and vanes extending into the airstream. One of Dryden's SR-71s was used for the Linear Aerospike Rocket Engine, or LASRE Experiment. Another earlier project consisted of a series of flights using the SR-71 as a science camera platform for NASA's Jet Propulsion Laboratory in Pasadena, California. An upward

  1. Edward (Ed) T. Schneider in Front of SR-71 Blackbird

    NASA Technical Reports Server (NTRS)

    1995-01-01

    SR-71 research pilot Ed Schneider is pictured here in front of an SR-71 Blackbird on the ramp at the Dryden Flight Research Center, Edwards, California. Schneider became a NASA research pilot at Dryden in 1983. Data from the SR-71 program will be used to aid designers of future supersonic aircraft and propulsion systems. He retired as a NASA research pilot in September 2000. Two SR-71 aircraft have been used by NASA as testbeds for high-speed and high-altitude aeronautical research. The aircraft, an SR-71A and an SR-71B pilot trainer aircraft, have been based here at NASA's Dryden Flight Research Center, Edwards, California. They were transferred to NASA after the U.S. Air Force program was cancelled. As research platforms, the aircraft can cruise at Mach 3 for more than one hour. For thermal experiments, this can produce heat soak temperatures of over 600 degrees Fahrenheit (F). This operating environment makes these aircraft excellent platforms to carry out research and experiments in a variety of areas -- aerodynamics, propulsion, structures, thermal protection materials, high-speed and high-temperature instrumentation, atmospheric studies, and sonic boom characterization. The SR-71 was used in a program to study ways of reducing sonic booms or over pressures that are heard on the ground, much like sharp thunderclaps, when an aircraft exceeds the speed of sound. Data from this Sonic Boom Mitigation Study could eventually lead to aircraft designs that would reduce the 'peak' overpressures of sonic booms and minimize the startling affect they produce on the ground. One of the first major experiments to be flown in the NASA SR-71 program was a laser air data collection system. It used laser light instead of air pressure to produce airspeed and attitude reference data, such as angle of attack and sideslip, which are normally obtained with small tubes and vanes extending into the airstream. One of Dryden's SR-71s was used for the Linear Aerospike Rocket Engine, or

  2. STS-58 Landing at Edwards with Drag Chute

    NASA Technical Reports Server (NTRS)

    1993-01-01

    A drag chute slows the space shuttle Columbia as it rolls to a perfect landing concluding NASA's longest mission at that time, STS-58, at the Ames-Dryden Flight Research Facility (later redesignated the Dryden Flight Research Center), Edwards, California, with a 8:06 a.m. (PST) touchdown 1 November 1993 on Edward's concrete runway 22. The planned 14 day mission, which began with a launch from Kennedy Space Center, Florida, at 7:53 a.m. (PDT), October 18, was the second spacelab flight dedicated to life sciences research. Seven Columbia crewmembers performed a series of experiments to gain more knowledge on how the human body adapts to the weightless environment of space. Crewmembers on this flight included: John Blaha, commander; Rick Searfoss, pilot; payload commander Rhea Seddon; mission specialists Bill MacArthur, David Wolf, and Shannon Lucid; and payload specialist Martin Fettman. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space

  3. Translational mini-review series on vaccines: The Edward Jenner Museum and the history of vaccination.

    PubMed

    Morgan, A J; Parker, S

    2007-03-01

    Edward Jenner's discovery of vaccination must rank as one of the most important medical advances of all time and is a prominent example of the power of rational enquiry being brought to bear during the Age of Enlightenment in 18th century Europe. In the modern era many millions of lives are saved each year by vaccines that work essentially on the same principles that were established by Edward Jenner more than 200 years ago. His country home in Berkeley, Gloucestershire, is where he carried out his work and where he spent most of his life. The building is now a museum in which the life and times of Jenner are commemorated including not only the discovery of smallpox vaccination but also his other important scientific contributions to natural history and medicine. The trustees of the Edward Jenner museum are committed to promoting the museum as a real and "virtual" educational centre that is both entertaining and informative.

  4. Translational mini-review series on vaccines: The Edward Jenner Museum and the history of vaccination.

    PubMed

    Morgan, A J; Parker, S

    2007-03-01

    Edward Jenner's discovery of vaccination must rank as one of the most important medical advances of all time and is a prominent example of the power of rational enquiry being brought to bear during the Age of Enlightenment in 18th century Europe. In the modern era many millions of lives are saved each year by vaccines that work essentially on the same principles that were established by Edward Jenner more than 200 years ago. His country home in Berkeley, Gloucestershire, is where he carried out his work and where he spent most of his life. The building is now a museum in which the life and times of Jenner are commemorated including not only the discovery of smallpox vaccination but also his other important scientific contributions to natural history and medicine. The trustees of the Edward Jenner museum are committed to promoting the museum as a real and "virtual" educational centre that is both entertaining and informative. PMID:17302886

  5. Translational Mini-Review Series on Vaccines: The Edward Jenner Museum and the history of vaccination

    PubMed Central

    Morgan, A J; Parker, S

    2007-01-01

    Edward Jenner's discovery of vaccination must rank as one of the most important medical advances of all time and is a prominent example of the power of rational enquiry being brought to bear during the Age of Enlightenment in 18th century Europe. In the modern era many millions of lives are saved each year by vaccines that work essentially on the same principles that were established by Edward Jenner more than 200 years ago. His country home in Berkeley, Gloucestershire, is where he carried out his work and where he spent most of his life. The building is now a museum in which the life and times of Jenner are commemorated including not only the discovery of smallpox vaccination but also his other important scientific contributions to natural history and medicine. The trustees of the Edward Jenner museum are committed to promoting the museum as a real and “virtual” educational centre that is both entertaining and informative. PMID:17302886

  6. Investigating groundwater flow between Edwards and Trinity aquifers in central Texas.

    PubMed

    Wong, C I; Kromann, J S; Hunt, B B; Smith, B A; Banner, J L

    2014-01-01

    Understanding the nature of communication between aquifers can be challenging when using traditional physical and geochemical groundwater sampling approaches. This study uses two multiport wells completed within Edwards and Trinity aquifers in central Texas to determine the degree of groundwater inter-flow between adjacent aquifers. Potentiometric surfaces, hydraulic conductivities, and groundwater major ion concentrations and Sr isotope values were measured from multiple zones within three hydrostratigraphic units (Edwards and Upper and Middle Trinity aquifers). Physical and geochemical data from the multiport wells were combined with historical measurements of groundwater levels and geochemical compositions from the region to characterize groundwater flow and identify controls on the geochemical compositions of the Edwards and Trinity aquifers. Our results suggest that vertical groundwater flow between Edwards and Middle Trinity aquifers is likely limited by low permeability, evaporite-rich units within the Upper and Middle Trinity. Potentiometric surface levels in both aquifers vary with changes in wet vs. dry conditions, indicating that recharge to both aquifers occurs through distinct recharge areas. Geochemical compositions in the Edwards, Upper, and Middle Trinity aquifers are distinct and likely reflect groundwater interaction with different lithologies (e.g., carbonates, evaporites, and siliceous sediments) as opposed to mixing of groundwater between the aquifers. These results have implications for the management of these aquifers as they indicate that, under current conditions, pumping of either aquifer will likely not induce vertical cross-formational flow between the aquifers. Inter-flow between the Trinity and the Edwards aquifers, however, should be reevaluated as pumping patterns and hydrogeologic conditions change.

  7. Investigating groundwater flow between Edwards and Trinity aquifers in central Texas.

    PubMed

    Wong, C I; Kromann, J S; Hunt, B B; Smith, B A; Banner, J L

    2014-01-01

    Understanding the nature of communication between aquifers can be challenging when using traditional physical and geochemical groundwater sampling approaches. This study uses two multiport wells completed within Edwards and Trinity aquifers in central Texas to determine the degree of groundwater inter-flow between adjacent aquifers. Potentiometric surfaces, hydraulic conductivities, and groundwater major ion concentrations and Sr isotope values were measured from multiple zones within three hydrostratigraphic units (Edwards and Upper and Middle Trinity aquifers). Physical and geochemical data from the multiport wells were combined with historical measurements of groundwater levels and geochemical compositions from the region to characterize groundwater flow and identify controls on the geochemical compositions of the Edwards and Trinity aquifers. Our results suggest that vertical groundwater flow between Edwards and Middle Trinity aquifers is likely limited by low permeability, evaporite-rich units within the Upper and Middle Trinity. Potentiometric surface levels in both aquifers vary with changes in wet vs. dry conditions, indicating that recharge to both aquifers occurs through distinct recharge areas. Geochemical compositions in the Edwards, Upper, and Middle Trinity aquifers are distinct and likely reflect groundwater interaction with different lithologies (e.g., carbonates, evaporites, and siliceous sediments) as opposed to mixing of groundwater between the aquifers. These results have implications for the management of these aquifers as they indicate that, under current conditions, pumping of either aquifer will likely not induce vertical cross-formational flow between the aquifers. Inter-flow between the Trinity and the Edwards aquifers, however, should be reevaluated as pumping patterns and hydrogeologic conditions change. PMID:24033308

  8. Geologic history and hydrogeologic setting of the Edwards-Trinity aquifer system, west-central Texas

    USGS Publications Warehouse

    Barker, R.A.; Bush, P.W.; Baker, E.T.

    1994-01-01

    Because the diagenetic effects of cementation, recrystallization, and mineral replacement diminish the hydraulic conductivity of most rocks composing the Trinity and Edwards-Trinity aquifers, transmissivity values average less than 10,000 feet squared per day over more than 90 percent of the study area. However, the effects of tectonic fractures and dissolution in the Balcones fault zone cause transmissivity values to average about 750,000 feet squared per day in the Edwards aquifer, which occupies less than 10 percent of the study area.

  9. Favorable evolution of a 43-year-old Starr-Edwards valve in the tricuspid position.

    PubMed

    Aludaat, Chadi; Gay, Arnaud; Guetlin, Amina; Nafeh-Bizet, Catherine; Bessou, Jean-Paul; Doguet, Fabien

    2012-09-01

    The durability of a Starr-Edwards valve implanted in the tricuspid position in 1967 to treat Ebstein's disease with tricuspid valve regurgitation. At surgery, cardiac permanent pacing for postoperative complete atrioventricular block was achieved using a nuclear-powered pacemaker (NP). Although the 43rd year of cardiologic follow up was free from complications, the patient--a 74-year-old woman--suffered symptomatic mitral regurgitation and underwent a redo mitral valve replacement, during which the Starr-Edwards valve and NP were left in place.

  10. Patient with a Starr-Edwards prosthesis in the aortic position for 40 years.

    PubMed

    Miranda, Matheus; do Nascimento, Luciene; Haddad, Michel Raineri; Haddad, William Teixeira; Haddad, William Teixeira; Buffolo, Enio

    2013-09-01

    Herein is reported the case of a patient who presented initially with aortic insufficiency and a fistula between the sinus of Valsalva and right atrium when aged 31 years. Closure of the fistula and replacement of the aortic valve with a Starr-Edwards A-9 caged-ball prosthesis was performed in 1972, since when the valve has survived for 40 years without dysfunction. This is one of the longest follow ups of the Starr-Edwards prosthesis reported, and highlights the possibility of acceptable valve performance over long periods of time.

  11. Dryden Fllight Reseach Facility, Edwards, California STA (Shuttle Training Aircraft, Gulf Stream II)

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Dryden Fllight Reseach Facility, Edwards, California STA (Shuttle Training Aircraft, Gulf Stream II) flys chase as STS-41returns from it's mission to Deploy Ulysses Spacecraft... Discovery's main gear is about to touch down at Edwards Air Foce Base to end a four-day mission in space for it's five-man crew. The vehicle landed at 6:57 a.m. Onboard the spacecraft were Astronauts Richard N. Richards, Robert D Cabana, William M Sheperd, Bruce E. Melnick and Thomas D. Akers.

  12. 75 FR 8106 - Don Edwards San Francisco Bay National Wildlife Refuge, Alameda, Santa Clara, and San Mateo...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... Fish and Wildlife Service Don Edwards San Francisco Bay National Wildlife Refuge, Alameda, Santa Clara, and San Mateo Counties, CA AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice of intent to...) and Environmental Assessment (EA) for the Don Edwards San Francisco Bay National Wildlife...

  13. Geologic framework and hydrogeologic characteristics of the Edwards aquifer outcrop (Barton Springs segment), northeastern Hays and southwestern Travis Counties, Texas

    USGS Publications Warehouse

    Small, Ted A.; Hanson, John A.; Hauwert, Nico M.

    1996-01-01

    In the Barton Springs segment of the Edwards aquifer, the aquifer probably is most vulnerable to surface contamination in the rapidly urbanizing areas on the Edwards aquifer outcrop. Contamination can result from spills or leakage of hazardous materials; or runoff on the intensely faulted and fractured, karstic limestone outcrops characteristic of the recharge zone.

  14. Diffuse-flow conceptualization and simulation of the Edwards Aquifer, San Antonio Region, Texas

    USGS Publications Warehouse

    Lindgren, R.J.

    2006-01-01

    A numerical ground-water-flow model (hereinafter, the conduit-flow Edwards aquifer model) of the karstic Edwards aquifer in south-central Texas was developed for a previous study on the basis of a conceptualization emphasizing conduit development and conduit flow, and included simulating conduits as one-cell-wide, continuously connected features. Uncertainties regarding the degree to which conduits pervade the Edwards aquifer and influence ground-water flow, as well as other uncertainties inherent in simulating conduits, raised the question of whether a model based on the conduit-flow conceptualization was the optimum model for the Edwards aquifer. Accordingly, a model with an alternative hydraulic conductivity distribution without conduits was developed in a study conducted during 2004-05 by the U.S. Geological Survey, in cooperation with the San Antonio Water System. The hydraulic conductivity distribution for the modified Edwards aquifer model (hereinafter, the diffuse-flow Edwards aquifer model), based primarily on a conceptualization in which flow in the aquifer predominantly is through a network of numerous small fractures and openings, includes 38 zones, with hydraulic conductivities ranging from 3 to 50,000 feet per day. Revision of model input data for the diffuse-flow Edwards aquifer model was limited to changes in the simulated hydraulic conductivity distribution. The root-mean-square error for 144 target wells for the calibrated steady-state simulation for the diffuse-flow Edwards aquifer model is 20.9 feet. This error represents about 3 percent of the total head difference across the model area. The simulated springflows for Comal and San Marcos Springs for the calibrated steady-state simulation were within 2.4 and 15 percent of the median springflows for the two springs, respectively. The transient calibration period for the diffuse-flow Edwards aquifer model was 1947-2000, with 648 monthly stress periods, the same as for the conduit-flow Edwards

  15. Cleveland's Multicultural Librarian: Eleanor (Edwards) Ledbetter, 1870-1954

    ERIC Educational Resources Information Center

    Jones, Plummer Alston, Jr.

    2013-01-01

    Eleanor (Edwards) Ledbetter, who served immigrant populations in Cleveland throughout most of the Progressive Era and the Great Depression, was one of the first librarians to advocate for multiculturalism (then called cultural pluralism) as opposed to Americanism. In providing multicultural and multilingual library services for immigrants,…

  16. Dyadic Power Theory, Touch, and Counseling Psychology: A Response to Smith, Vogel, Madon, and Edwards (2011)

    ERIC Educational Resources Information Center

    Dunbar, Norah E.; Abra, Gordon

    2012-01-01

    Smith, Vogel, Madon, and Edwards' (2011) recent article tested dyadic power theory (DPT) by examining the use of touch as a compliance-gaining tactic in the conflicts of married couples. In this response, we raise a methodological issue about the touch behaviors examined by Smith et al. and also pose a theoretical critique that their test of DPT…

  17. "Affection in Education": Edward Carpenter, John Addington Symonds and the Politics of Greek Love

    ERIC Educational Resources Information Center

    Quinn, Josephine Crawley; Brooke, Christopher

    2011-01-01

    The paper examines Edward Carpenter's 1899 essay on education that defended the value of powerful same-sex attachments, either between older and younger boys or between teachers and pupils, in the context of Victorian ideologies of same-sex affection. Linda Dowling has described how "a homosexual counterdiscourse able to justify male love in ideal…

  18. Tackling Problems through Lateral Thinking. An Interview with Edward de Bono.

    ERIC Educational Resources Information Center

    Brodinsky, Ben

    1985-01-01

    In this interview, Edward de Bono says critical or logical thinking in lockstep fashion is necessary but not sufficient because we need not only the ability to critique ideas, but to create them. Creative or lateral thinking arrives at solutions by attacking problems "laterally" or "sideways." (DCS)

  19. Edward Y. Hartshorne and the Reopening of German Universities, 1945-1946: His Personal Account.

    ERIC Educational Resources Information Center

    Tent, James F.

    1997-01-01

    Characterizes U.S. Edward Y. Hartshorne as a "manager of German social recovery." An instructor at Harvard University and protege of sociologist Talcott Parsons, Hartshorne was instrumental in the post-war reopening of German universities. Discusses Hartshorne's activities in military intelligence and psychological warfare, as well as the…

  20. The Use of Technology in Prince Edward Island (Canada) High Schools: Perceptions of School Leaders

    ERIC Educational Resources Information Center

    Preston, Jane P; Moffatt, Lyndsay; Wiebe, Sean; McAuley, Alexander; Campbell, Barbara; Gabriel, Martha

    2015-01-01

    The purpose of this paper is to document the perceptions of school leaders regarding the technological use, skills, and attitudes of high school teachers. Using a qualitative research approach, 11 educational leaders from Prince Edward Island (Canada) were individually interviewed. Participants represented the Department of Education, principals,…

  1. The Reconciliation of W. Edwards Deming and John Dewey: An Exploration of Similarities in Motivation Theory.

    ERIC Educational Resources Information Center

    Towns, William C.

    1996-01-01

    Interrogates similarities and misconceptions common to W. Edwards Deming and John Dewey, examining a reconciliation of the two within the context of motivation theory and concluding that Deming and Dewey are very similar in general outlook and the shared belief in the integrity of the individual within the social system. (SM)

  2. On the Production of Expert Knowledge: Revisiting Edward Said's Work on the Intellectual

    ERIC Educational Resources Information Center

    Dimitriadis, Greg

    2006-01-01

    Edward Said is deservedly well known for his literary insights on Orientalism. Yet, his work on the nature of the intellectual is equally important and particularly critical for navigating this moment of political, cultural, and economic retrenchment. In this essay I will explore the contours of Said's work on the intellectual. I argue that Said…

  3. Understanding "Together and Apart": A Case Study of Edward's Explorations at Nursery

    ERIC Educational Resources Information Center

    Arnold, Cath

    2009-01-01

    Edward was one of 58 children studied by workers and parents as part of a study on Well-being and Resilience at the Pen Green Nursery. Within the larger study, eight children were studied in greater depth in order to explore connections between cognitive and emotional development. Schematic theory and attachment theory were used as frameworks for…

  4. Thirty-Seven-Year Durability of a Starr-Edwards Aortic Prosthesis

    PubMed Central

    Ozkokeli, Mehmet; Ates, Mehmet; Ekinci, Abdurrahman; Akcar, Murat

    2005-01-01

    We report the case of a patient who was diagnosed with prosthetic valve endocarditis caused by Staphylococcus aureus. He had undergone aortic valve replacement with a Starr-Edwards prosthesis 37 years earlier. Because of uncontrolled infection despite antibiotic treatment, the patient underwent successful surgical replacement of the prosthetic valve. PMID:15902834

  5. Premature valve closure in patients with a mitral Starr-Edwards prosthesis and aortic incompetence

    PubMed Central

    Agnew, T. M.; Carlisle, R.

    1970-01-01

    A mitral Starr-Edwards ball valve has, in three patients with concomitant aortic incompetence, permitted recognition of intermittent premature valve closure by auscultation and this has been documented by phonocardiograms. In two instances the observations were confirmed during cardiac catheterization. The features of premature Starr valve closure are described and the mechanism is discussed. Images PMID:5433303

  6. Caleb Hillier Parry (1755-1822): clinician, scientist, friend of Edward Jenner (1749-1823).

    PubMed

    Larner, Andrew J

    2005-11-01

    This article summarizes briefly the life and work of Dr Caleb Hillier Parry (1755-1822), a friend of Dr Edward Jenner. He made original clinical observations, including the bradycardic effect of carotid artery compression, and the association of thyroid enlargement with cardiac disease. He also undertook experimental work and published extensively, including the first book devoted to angina. PMID:16244710

  7. Pickering, Edward Charles (1846-1919) and Pickering, William Henry (1858-1938)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Astronomers—two brothers. Born in Boston, MA, Edward became director of the Harvard College Observatory and observed the brightnesses of 45 000 stars. He hired a number of women, including WILLIAMINA P FLEMING, ANNIE J CANNON, Antonia Maury and HENRIETTA LEAVITT, and produced the Henry Draper Catalog, classifying the spectra of hundreds of thousands of stars. He and HERMANN CARL VOGEL independent...

  8. It Really Is All about the Child: An Interview with Dr. Edward Hallowell

    ERIC Educational Resources Information Center

    Peters, Dane L.

    2012-01-01

    In a decade when brain research has helped people understand learning difficulties in children, and people have seen increased media attention on the use of medications to treat attention deficit/hyperactivity disorder (ADHD) in children and adults, Dr. Edward (Ned) Hallowell has worked tirelessly to educate the medical profession, parents,…

  9. James Edward Scott: The Leadership Journey of a Senior-Level African American Student Affairs Officer

    ERIC Educational Resources Information Center

    Willis, Salatha T.

    2013-01-01

    The purpose of this study was to examine, understand, and describe the life, leadership, and influence of Dr. James Edward Scott on higher education and more specifically student affairs; as one of the most well-known and respected African American male chief student affairs officers in the late 20th and early 21st centuries. Using a qualitative…

  10. Caleb Hillier Parry (1755-1822): clinician, scientist, friend of Edward Jenner (1749-1823).

    PubMed

    Larner, Andrew J

    2005-11-01

    This article summarizes briefly the life and work of Dr Caleb Hillier Parry (1755-1822), a friend of Dr Edward Jenner. He made original clinical observations, including the bradycardic effect of carotid artery compression, and the association of thyroid enlargement with cardiac disease. He also undertook experimental work and published extensively, including the first book devoted to angina.

  11. Race, Ruralism, and Reformation: William J. Edwards and Snow Hill Institute, 1894-1915.

    ERIC Educational Resources Information Center

    Cooper, Arnold

    This article examines the Snow Hill Institute, one of several 19th-century industrial schools founded for rural Southern black students, following the model of Booker T. Washington's Tuskegee Institute. This case study provides a sketch of William J. Edwards, an early Tuskegee alumnus and founder of the Snow Hill Institute in Wilcox County,…

  12. STS-29 Discovery, OV-103, lands on Edwards AFB concrete runway 22

    NASA Technical Reports Server (NTRS)

    1989-01-01

    STS-29 Discovery, Orbiter Vehicle (OV) 103, main landing gear (MLG) touches down at a speed of approximately 205 knots (235 miles per hour) on concrete runway 22 at Edwards Air Force Base (AFB), California. Nose landing gear (NLG) is deployed and rides above runway surface prior touchdown. Mojave desert scrub brush appears in the foreground with mountain range appearing in the background.

  13. Enhancing Undergraduates' Capabilities through Team-Based Competitions: The Edward Jones Challenge

    ERIC Educational Resources Information Center

    Umble, Elisabeth J.; Umble, Michael; Artz, Kendall

    2008-01-01

    The Edward Jones Company recently initiated financial sponsorship of team-based competitions in six undergraduate business core classes at Baylor University. The challenges were chosen to take place in an introductory freshman business class, Managerial Accounting, Principles of Marketing, Corporate Finance, Operations Management, and Strategic…

  14. Southern Stalemate: Five Years without Public Education in Prince Edward County, Virginia

    ERIC Educational Resources Information Center

    Bonastia, Christopher

    2012-01-01

    In 1959, Virginia's Prince Edward County closed its public schools rather than obey a court order to desegregate. For five years, black children were left to fend for themselves while the courts decided if the county could continue to deny its citizens public education. Investigating this remarkable and nearly forgotten story of local, state, and…

  15. This Earthly World: Edward Said, the Praxis of Secular Humanisms and Situated Cosmopolitanisms

    ERIC Educational Resources Information Center

    Roman, Leslie G.

    2006-01-01

    This essay unearths the educational and socio-political implications of Edward W. Said's work for our understanding of what a secular humanism might mean in the highly charged atmosphere of the post-Cold War and September 11 discourses that have pervaded the USA and, to varying degrees, other parts of the world. It asks what it means to move…

  16. Landing of STS-59 Shuttle Endeavour at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The main landing gear of the Space Shuttle Endeavour touches down at Edwards Air Force Base to complete the 11 day STS-59/SRL-1 mission. Landing occured at 9:54 a.m., April 20, 1994. Mission duration was 11 days, 5 hours, 49 minutes.

  17. Vulnerability of ground water to contamination, Edwards Aquifer recharge zone, Bexar County, Texas, 1998

    USGS Publications Warehouse

    Clark, Allan K.

    2000-01-01

    The Edwards aquifer, one of the most productive carbonate-rock aquifers in the Nation, is composed of the Kainer and Person Formations of the Edwards Group plus the overlying Georgetown Formation. Most recharge to the Edwards aquifer results from the percolation of streamflow loss and the infiltration of precipitation through porous parts of the recharge zone. Residential and commercial development is increasing, particularly in Bexar County in south-central Texas, atop the densely fractured and steeply faulted recharge zone. The increasing development has increased the vulnerability of ground water to contamination by spillage or leakage of waste materials, particularly fluids associated with urban runoff and (or) septic-tank leachate. This report describes a method of assessing the vulnerability of ground water to contamination in the Edwards aquifer recharge zone. The method is based on ratings of five natural features of the area: (1) hydraulic properties of outcropping hydrogeologic units; (2) presence or absence of faults; (3) presence or absence of caves and (or) sinkholes; (4) slope of land surface; and (5) permeability of soil. The sum of the ratings for the five natural features was used to develop a map showing the recharge zone's vulnerability to ground-water contamination.

  18. Diaspora as Catastrophe, Diaspora as a Mission and the Post-Colonial Philosophy of Edward Said

    ERIC Educational Resources Information Center

    Pappe, Ilan

    2010-01-01

    Edward Said the refugee could not easily allow himself to join in the celebration of demythologizing nationalism. His Palestinianism had to coexist, uncomfortably, with his universalism. Time made this necessary coexistence an asset, not a liability, and this in fact was his political legacy for the future: Jews and Palestinians would have to…

  19. The Empty Cup: "Teaching for Understanding" at 21st Century Edward Waters College. Occasional Paper #6

    ERIC Educational Resources Information Center

    Fluellen, Jerry E., Jr.

    2008-01-01

    What happens in a final project that fosters teaching for understanding? That inquiry calls to mind the Taoist belief that emptiness makes a cup useful. In the context of this paper, the inquiry organizes a narrative about how teaching for understanding surfaced in a "Theories of Learning" course at Edward Waters College. At a deeper level, the…

  20. Obituary: Edward R. (Ted) Harrison, 1919-2007

    NASA Astrophysics Data System (ADS)

    Irvine, William M.; Arny, Thomas T.; Trimble, Virginia

    2007-12-01

    Cosmologist Edward R. (Ted) Harrison, emeritus Distinguished University Professor of Physics and Astronomy at the University of Massachusetts Amherst, died on 29 January 2007 in his retirement city of Tucson, Arizona, where he was adjunct professor at the Steward Observatory, University of Arizona. The cause of death was colon cancer. He is survived by a sister, brother, and daughter. (A son died in 2000.) Perhaps best known for his work on the growth of fluctuations in the expanding universe and his books on cosmology for the dedicated layperson, Ted had extremely broad interests, and he published more than 200 papers in space sciences, plasma physics, high-energy physics, physical chemistry, and, principally, many aspects of astrophysics. He was a Fellow of the American Physical Society, the American Association for the Advancement of Science, the Royal Astronomical Society, and the Institute of Physics (UK). Ted Harrison was born 8 January 1919 in London, England. His parents were Robert Harrison and Daisy Harrison (nee White). His education at Sir John Cass College, London University, was interrupted by the Second World War, during which he served for six years with the British Army in various campaigns, ultimately acting as Radar Adviser to the Northern Area of the Egyptian Army. It was during the latter service that he met his wife Photeni (nee Marangas). Following the War, Ted became a British Civil Servant, at first with the Atomic Energy Research Establishment in Harwell and then at the Rutherford High Energy Laboratory. During this period he acquired the equivalent of university degrees, becoming a graduate, then an Associate, and finally a Fellow of the Institute of Physics. His somewhat unorthodox education may have contributed to his broad interests and his very intuitive and physical approach to scientific problems. The latter became the bane of generations of graduate students, who might find themselves asked on their physics qualifying exams to

  1. STS-36 on Edwards Runway with Recovery Personnel

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Personnel and equipment converge on the orbiter Atlantis to begin servicing the spacecraft following its landing 4 March 1990, at NASA's then Ames-Dryden Flight Research Facility, Edwards, California. Mission elapsed time for the Department of Defense mission was 4 days, 10 hours, 19 minutes and 15 seconds. Actual landing time was 10:08 a.m. Post-landing servicing by the recovery convoy is carried out after each Space Shuttle landing and includes safety checks for flammable and toxic gases escaping from systems aboard the orbiters, hooking up engine fuel purge and equipment coolant lines, and inspecting the brakes before the vehicle is towed from the runway to the shuttle facility at Dryden where it is prepared for the ferry flight back to the Kennedy Space Center in Florida. Up to 24 vehicles and scores of personnel make up the landing recovery convoys at Dryden. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are designed

  2. Obituary: Edward R. (Ted) Harrison, 1919-2007

    NASA Astrophysics Data System (ADS)

    Irvine, William M.; Arny, Thomas T.; Trimble, Virginia

    2007-12-01

    Cosmologist Edward R. (Ted) Harrison, emeritus Distinguished University Professor of Physics and Astronomy at the University of Massachusetts Amherst, died on 29 January 2007 in his retirement city of Tucson, Arizona, where he was adjunct professor at the Steward Observatory, University of Arizona. The cause of death was colon cancer. He is survived by a sister, brother, and daughter. (A son died in 2000.) Perhaps best known for his work on the growth of fluctuations in the expanding universe and his books on cosmology for the dedicated layperson, Ted had extremely broad interests, and he published more than 200 papers in space sciences, plasma physics, high-energy physics, physical chemistry, and, principally, many aspects of astrophysics. He was a Fellow of the American Physical Society, the American Association for the Advancement of Science, the Royal Astronomical Society, and the Institute of Physics (UK). Ted Harrison was born 8 January 1919 in London, England. His parents were Robert Harrison and Daisy Harrison (nee White). His education at Sir John Cass College, London University, was interrupted by the Second World War, during which he served for six years with the British Army in various campaigns, ultimately acting as Radar Adviser to the Northern Area of the Egyptian Army. It was during the latter service that he met his wife Photeni (nee Marangas). Following the War, Ted became a British Civil Servant, at first with the Atomic Energy Research Establishment in Harwell and then at the Rutherford High Energy Laboratory. During this period he acquired the equivalent of university degrees, becoming a graduate, then an Associate, and finally a Fellow of the Institute of Physics. His somewhat unorthodox education may have contributed to his broad interests and his very intuitive and physical approach to scientific problems. The latter became the bane of generations of graduate students, who might find themselves asked on their physics qualifying exams to

  3. PRELIMINARY ANALYSIS OF THE FINAL MULTICENTER INVESTIGATION OF RHEOPHERESIS FOR AGE RELATED MACULAR DEGENERATION (AMD) TRIAL (MIRA-1) RESULTS

    PubMed Central

    Pulido, Jose S.; Winters, Jeffrey L.; Boyer, David

    2006-01-01

    Purpose To present an initial evaluation of the final data from the Multicenter Investigation of Rheopheresis for age-related macular degeneration (AMD) (MIRA-1) trial. This was a 12-month randomized, prospective, multicenter, double-masked, placebo-controlled, Food and Drug Administration approved clinical trial designed to compare rheopheresis treatment with placebo-control treatment. Methods Patients that had nonexudative age-related macular degeneration (AMD) and certain hemorheologic abnormalities were randomized to either rheopheresis or sham treatment in a 2:1 fashion. Best-corrected visual acuity was determined before and at 3, 6, 9, and 12 months following treatment. Adverse events were also recorded. Results A total of 216 patients were randomized. Of these, 18 were not included in the vision or adverse events evaluation because they did not complete one treatment. This decreased the number of patients that were evaluated for adverse events to 198 patients. In this group, there were 27 serious adverse events, but only 1.8 % of treatments were suspended because of adverse events. At 12 months, there were 104 treated patients and 63 placebo patients that had follow-up. The treated patients had a logMAR vision improvement of 0.02 ± 0.213, and the placebo patients had a vision improvement of 0.02 ± 0.20. This was not statistically significant (P = .977). The repeated measure P value for the entire time interval was not significant (P = .69). There appeared to be patients entered into the study that did not meet inclusion criteria. Excluding 37% of the treated patients and 29% of the placebo data from the analysis, there appeared to be statistically significant improvement in the treated patients compared to the control patients at 1 year with a P value of .001 (repeated measures P value = .01). Conclusions At best this was a flawed study in that 37% of the treated cases did not meet inclusion criteria, and at worst there was no evidence of effect. Even

  4. Bailout perventricular pulmonary valve implantation following failed percutaneous attempt using the Edwards Sapien transcatheter heart valve.

    PubMed

    Cubeddu, Roberto J; Hijazi, Ziyad M

    2011-02-01

    Percutaneous pulmonary valve implantation has emerged as an attractive and less invasive alternative to open-heart surgery. Nevertheless, major technical challenges and procedural complications may still occur. We report a 44-year-old woman with severe dextroscoliosis, and history of Tetralogy of Fallot repair, who underwent an attempt at percutaneous implantation of a 23-mm Edwards SAPIEN transcatheter heart valve (THV) for recurrent stenosis of the right ventricle to pulmonary artery conduit. The procedure was complicated by valve migration into the right ventricle requiring emergent surgical removal using inflow-occlusion technique to avoid cardiopulmonary bypass. A hybrid off-pump perventricular approach was then used in the operating room to successfully implant a 26-mm Edwards Sapien THV under fluoroscopic guidance. © 2010 Wiley-Liss, Inc. PMID:20518008

  5. Hot, cold, and annual reference atmospheres for Edwards Air Force Base, California (1975 version)

    NASA Technical Reports Server (NTRS)

    Johnson, D. L.

    1975-01-01

    Reference atmospheres pertaining to summer (hot), winter (cold), and mean annual conditions for Edwards Air Force Base, California, are presented from surface to 90 km altitude (700 km for the annual model). Computed values of pressure, kinetic temperature, virtual temperature, and density and relative differences percentage departure from the Edwards reference atmospheres, 1975 (ERA-75) of the atmospheric parameters versus altitude are tabulated in 250 m increments. Hydrostatic and gas law equations were used in conjunction with radiosonde and rocketsonde thermodynamic data in determining the vertical structure of these atmospheric models. The thermodynamic parameters were all subjected to a fifth degree least-squares curve-fit procedure, and the resulting coefficients were incorporated into Univac 1108 computer subroutines so that any quantity may be recomputed at any desired altitude using these subroutines.

  6. Granular statistical mechanics - Building on the legacy of Sir Sam Edwards

    NASA Astrophysics Data System (ADS)

    Blumenfeld, Raphael

    When Sir Sam Edwards laid down the foundations for the statistical mechanics of jammed granular materials he opened a new field in soft condensed matter and many followed. In this presentation we review briefly the Edwards formalism and some of its less discussed consequences. We point out that the formalism is useful for other classes of systems - cellular and porous materials. A certain shortcoming of the original formalism is then discussed and a modification to overcome it is proposed. Finally, a derivation of an equation of state with the new formalism is presented; the equation of state is analogous to the PVT relation for thermal gases, relating the volume, the boundary stress and measures of the structural and stress fluctuations. NUDT, Changsha, China, Imperial College London, UK, Cambridge University, UK.

  7. A case study of contaminants on military ranges: Camp Edwards, Massachusetts, USA.

    PubMed

    Clausen, Jay; Robb, Joe; Curry, Diane; Korte, Nic

    2004-05-01

    An extensive investigation at the Camp Edwards, Massachusetts Military Reservation (MMR) demonstrates that assessment of groundwater and soil contamination at military ranges can be limited primarily to explosive-related compounds such as RDX, HMX, perchlorate, TNT and their transformation products. A modified analytical method is recommended to expand the list of explosives and to improve the detection limits. Analyses of metals, VOCs, SVOCs, and TICs are unnecessary. Soil samples may require the analyses of PAHs and PCNs for burn areas. Camp Edwards, as one of the few military ranges that have been exhaustively investigated for contaminants, is an ideal point of departure for evaluating other ranges. The permeable site soils promote leaching of contaminants and inhibit biotic and abiotic transformations. Moreover, the site has experienced an unusual extent of activities in its more than ninety years of active use. The recommendations in this report are based on data obtained for more than 200 analytes from more than 15,000 environmental samples.

  8. Invited commentary on 'Robert G Edwards and the Roman Catholic Church'.

    PubMed

    Head, Ivan Francis

    2011-06-01

    In this issue of Reproductive BioMedicine Online, Benagiano, Carrara and Filippi have produced a clearly written and comprehensive account of why the Roman Catholic Church has not welcomed the award of the 2010 Nobel Prize in Physiology and Medicine to Dr Robert G Edwards for the development of human IVF. I commend the article for its clarity and lucidity but attempt to point out some areas where disagreement even with its nuanced opposition to IVF may be legitimate. I try to make some simple comments that explain why this is so and I suggest some areas to which contemporary theology and philosophy can commit itself. But it is good to see even a nuanced response to the work of Robert G Edwards rather than a blanket condemnation.

  9. Cloth destruction and haemolysis with totally cloth-covered Starr-Edwards prostheses

    PubMed Central

    Schottenfeld, M.; Wisheart, J. D.; Ross, J. K.; Lincoln, J. C. R.; Ross, D. N.

    1971-01-01

    Four cases are described in which totally cloth-covered Starr-Edwards valves (model 2300) had to be removed. All were causing significant haemolysis, two in the absence of a peripheral leak. The principal operative finding was destruction of the Dacron covering the struts. Following replacement of these prostheses there was complete resolution of signs and symptoms. The possible causes of haemolysis and consequences of cloth destruction are discussed. Images PMID:5576531

  10. Reoperation on a Starr-Edwards ball valve without structural deterioration.

    PubMed

    Hayatsu, Yukihiro; Saito, Takeshi; Adachi, Osamu; Kumagai, Kiichiro; Akiyama, Masatoshi; Motoyoshi, Naotaka; Kawamoto, Shunsuke; Saiki, Yoshikatsu

    2012-12-01

    Accurate measurement of pressure gradients on echocardiography across a Starr-Edwards (SE) ball valve is difficult due to its unique flow pattern. The decision of indication for reoperation on the valve requires multifactorical evaluation. We report a surgical case with an aortic SE ball valve 43 years after implantation. There was no apparent structural deterioration on the ball per se, yet, remarkable pannus formation was noted beneath the sewing cuff in the left ventricular outflow tract.

  11. From LCME probation to compliance: the Marshall University Joan C Edwards School of Medicine experience

    PubMed Central

    Miller, Bobby; Dzwonek, Brian; McGuffin, Aaron; Shapiro, Joseph I

    2014-01-01

    The Joan C Edwards School of Medicine (Marshall University, Huntington, WV, USA) was placed on probation by the Liaison Committee on Medical Education (LCME) in June 2011. In the following 2 years, extensive changes were made to address the numerous citations that resulted in this probation. In October 2013, the LCME lifted probation. In this article, we detail the challenges and solutions identified relevant to our struggle with compliance. PMID:25337003

  12. Geologic Map of the Edwards Aquifer In Northern Medina and Northeastern Uvalde Counties, South-central Texas

    USGS Publications Warehouse

    Clark, Allan K.; Faith, Jason R.; Blome, Charles D.; Pedraza, Diana E.

    2006-01-01

    The southern segment of the Edwards aquifer in south-central Texas is one of the most productive subsurface reservoirs of potable water in the world, providing water of excellent quality to more than a million people in the San Antonio region, where the Environmental Protection Agency (EPA) has declared it to be a sole-source aquifer (van der Leeden and others, 1990). Depending on the depositional province within which the associated carbonate rocks originated (Maclay and Small, 1984), the Edwards aquifer is composed of several geologic formations (primarily limestone and dolostone) of Early Cretaceous age. Most water pumped from the Edwards aquifer comes form the Person and Kainer Formations, which were deposited over the San Marcos Platform. The principal source of ground water in study area is the Devils River Formation, which was deposited in the Devils River trend. The Devils River Formation provides large quantities of irrigation water to fertile bottomland areas of Medina and Uvalde Counties, where the success of farming and ranching activities has long depended upon water from the Edwards aquifer. The study area includes all of the Edwards aquifer recharge zone between the Sabinal River (on the west) and the Medina River (on the east) plus an updip fringe of the confined zone in east-central Uvalde and central Medina Counties. Over about ninety percent of the study area--within the Devils River trend--the Edwards aquifer is composed of the Georgetown Formation plus the underlying Devils River Formation. Over the remaining area--over the southwestern margin of the San Marcos platform--the Edwards aquifer consists of the Georgetown Formation plus the underlying Edwards Group (Rose, 1972), which comprises the Kainer and Person Formations.

  13. The Edwards Aquifer Water Resource Conflict: USDA Farm Program resource-use incentives?

    NASA Astrophysics Data System (ADS)

    Schaible, Glenn D.; McCarl, Bruce A.; Lacewell, Ronald D.

    1999-10-01

    This paper summarizes economic and hydrological analyses of the impacts of the 1990 and 1996 U.S. Department of Agriculture (USDA) farm programs on irrigation water withdrawals from the Edwards Aquifer in south central Texas and on aquifer-dependent spring flows that support threatened and endangered species. Economic modeling, a regional producer behavioral survey, as well as institutional and farm characteristic analyses are used to examine likely irrigation water-use impacts. Hydrologie modeling is used to examine spring flow effects. Study results show that 1990 USDA commodity programs caused producers to require less irrigation water, in turn increasing rather than decreasing aquifer spring flows. Market economic factors are the dominant criteria influencing producer irrigation decisions. Farm-tenure arrangements and aquifer management responsibilities of the Edwards Aquifer Authority indicate that the 1996 Farm Act's PFC payment program will not cause an increase in irrigation withdrawals. Broader actions such as long-term water supply enhancement/conservation programs, dry-year water-use reduction incentives and water markets all provide tools for Edwards water-use conflict resolution. USDA farm programs do not apparently play a material part in the total debate.

  14. Replacement of the Aortic and Mitral Valves Using the Starr-Edwards Ball-Valve Prosthesis

    PubMed Central

    Callaghan, John C.

    1964-01-01

    The aortic and mitral valves were replaced in 50 patients at the University of Alberta Hospital using the Starr-Edwards ball-valve prosthesis. The basis of the selection of 20 patients for isolated aortic valve replacement and 27 for mitral valve replacement using this type of prosthesis is presented, and the techniques of insertion of the aortic and mitral valve are described in detail. Of the 27 patients in whom the mitral valve was replaced by the Starr-Edwards prosthesis six died within 30 days of surgery and two after discharge from hospital at two and a half and four months, respectively. Left atrial thrombosis was the cause of death in four of these patients. In 20 patients in whom the aortic valve was replaced, four died in hospital and two died more than 30 days after returning home. Three of these six patients died from bleeding—the result of the use of anticoagulants. The difficulty in assessing whether or not anticoagulants are needed following replacement by a Starr-Edwards prosthesis is considered. It is felt, in our present state of knowledge, that anticoagulants should be used following mitral valve replacement but are probably not essential following replacement of the aortic valve. Two patients survived replacement of both aortic and mitral valves and have been followed up 18 months and seven months, respectively. ImagesFig. 1Fig. 2Fig. 4Fig. 5Fig. 7Fig. 9Fig. 10Fig. 11Fig. 12Fig. 13 PMID:14179062

  15. Behavior modification and human rights: A legacy of Edward Stanton Sulzer, 1930-1970

    PubMed Central

    Sulzer-Azaroff, Beth

    1981-01-01

    Edward Stanton Sulzer was born in New York City on June 4, 1930. He attended school in Laureltown, N.Y., until the age of 15, when, after two years of high school, he was admitted into the University of Chicago. Leaving prematurely due to his mother's death, he returned to New York to work in film production. Sulzer completed his undergraduate work at the City College of New York, studying film production and psychology. In 1953 he entered the doctoral program in clinical psychology at Teachers College, Columbia. Spending two years in the Army during his graduate training, his work was completed in 1958. He then joined the faculty of the Upstate Medical School of the State University of New York, Department of Psychiatry, moving on two years later to the Psychiatry Department at the University of Minnesota. In 1965 Sulzer moved to assume the directorship of the Behavior Modification Program, in the Rehabilitation Institute at Southern Illinois University, where he remained until his death on February 28, 1970. In observance of the 10th anniversary of the death of Edward Stanton Sulzer, these reminiscences are presented. They describe how an individual psychologist could affect the professional and personal lives of many. Edward Sulzer is described in terms of the environment that shaped his values, how they affected the actions of his students and clients, and how they are reflected in current social policy. The account leads to a conclusion that the actions of single individuals may influence the course of human events. PMID:22478535

  16. Molecular mapping of the Edwards syndrome phenotype to two noncontiguous regions on chromosome 18.

    PubMed Central

    Boghosian-Sell, L.; Mewar, R.; Harrison, W.; Shapiro, R. M.; Zackai, E. H.; Carey, J.; Davis-Keppen, L.; Hudgins, L.; Overhauser, J.

    1994-01-01

    In an effort to identify regions on chromosome 18 that may be critical in the appearance of the Edwards syndrome phenotype, we have analyzed six patients with partial duplication of chromosome 18. Four of the patients have duplications involving the distal half of 18q (18q21.1-qter) and are very mildly affected. The remaining two patients have most of 18q (18q12.1-qter) duplicated, are severely affected, and have been diagnosed with Edwards syndrome. We have employed FISH, using DNA probes from a chromosome 18-specific library, for the precise determination of the duplicated material in each of these patients. The clinical features and the extent of the chromosomal duplication in these patients were compared with four previously reported partial trisomy 18 patients, to identify regions of chromosome 18 that may be responsible for certain clinical features of trisomy 18. The comparative analysis confirmed that there is no single region on 18q that is sufficient to produce the trisomy 18 phenotype and identified two regions on 18q that may work in conjunction to produce the Edwards syndrome phenotype. In addition, correlative analysis indicates that duplication of 18q12.3-q22.1 may be associated with more severe mental retardation in trisomy 18 individuals. Images Figure 1 Figure 3 PMID:8079991

  17. Geologic framework and hydrogeologic characteristics of the Edwards aquifer, Uvalde County, Texas

    USGS Publications Warehouse

    Clark, Allan K.

    2003-01-01

    The Edwards aquifer in Uvalde County is composed of Lower Cretaceous carbonate (mostly dolomitic limestone) strata of the Devils River Formation in the Devils River trend and of the West Nueces, McKnight, and Salmon Peak Formations in the Maverick basin. Rocks in the Devils River trend are divided at the bottom of the Devils River Formation into the (informal) basal nodular unit. Maverick basin rocks are divided (informally) into the basal nodular unit of the West Nueces Formation; into lower, middle, and upper units of the McKnight Formation; and into lower and upper units of the Salmon Peak Formation. The Edwards aquifer overlies the (Lower Cretaceous) Glen Rose Limestone, which composes the lower confining unit of the Edwards aquifer. The Edwards aquifer is overlain by the (Upper Cretaceous) Del Rio Clay, the basal formation of the upper confining unit. Upper Cretaceous and (or) Lower Tertiary igneous rocks intrude all stratigraphic units that compose the Edwards aquifer, particularly in the southern part of the study area. The Balcones fault zone and the Uvalde salient are the principal structural features in the study area. The fault zone comprises mostly en echelon, high-angle, and down-to-the-southeast normal faults that trend mostly from southwest to northeast. The Uvalde salient?resulting apparently from a combination of crustal uplift, diverse faulting, and igneous activity?elevates the Edwards aquifer to the surface across the central part of Uvalde County. Downfaulted blocks associated with six primary faults?Cooks, Black Mountain, Blue Mountain, Uvalde, Agape, and Connor?juxtapose the Salmon Peak Formation (Lower Cretaceous) in central parts of the study area against Upper Cretaceous strata in the southeastern part. The carbonate rocks of the Devils River trend and the Maverick basin are products of assorted tectonic and depositional conditions that affected the depth and circulation of the Cretaceous seas. The Devils River Formation formed in a

  18. Near-infrared spectro-interferometry of Mira variables and comparisons to 1D dynamic model atmospheres and 3D convection simulations

    NASA Astrophysics Data System (ADS)

    Wittkowski, M.; Chiavassa, A.; Freytag, B.; Scholz, M.; Höfner, S.; Karovicova, I.; Whitelock, P. A.

    2016-03-01

    Aims: We aim at comparing spectro-interferometric observations of Mira variable asymptotic giant branch (AGB) stars with the latest 1D dynamic model atmospheres based on self-excited pulsation models (CODEX models) and with 3D dynamic model atmospheres including pulsation and convection (CO5BOLD models) to better understand the processes that extend the molecular atmosphere to radii where dust can form. Methods: We obtained a total of 20 near-infrared K-band spectro-interferometric snapshot observations of the Mira variables o Cet, R Leo, R Aqr, X Hya, W Vel, and R Cnc with a spectral resolution of about 1500. We compared observed flux and visibility spectra with predictions by CODEX 1D dynamic model atmospheres and with azimuthally averaged intensities based on CO5BOLD 3D dynamic model atmospheres. Results: Our visibility data confirm the presence of spatially extended molecular atmospheres located above the continuum radii with large-scale inhomogeneities or clumps that contribute a few percent of the total flux. The detailed structure of the inhomogeneities or clumps show a variability on time scales of 3 months and above. Both modeling attempts provided satisfactory fits to our data. In particular, they are both consistent with the observed decrease in the visibility function at molecular bands of water vapor and CO, indicating a spatially extended molecular atmosphere. Observational variability phases are mostly consistent with those of the best-fit CODEX models, except for near-maximum phases, where data are better described by near-minimum models. Rosseland angular diameters derived from the model fits are broadly consistent between those based on the 1D and the 3D models and with earlier observations. We derived fundamental parameters including absolute radii, effective temperatures, and luminosities for our sources. Conclusions: Our results provide a first observational support for theoretical results that shocks induced by convection and pulsation in the

  19. Millimeter and some near infra-red observations of short-period Miras and other AGB stars

    NASA Astrophysics Data System (ADS)

    Groenewegen, M. A. T.; Baas, F.; Blommaert, J. A. D. L.; Stehle, R.; Josselin, E.; Tilanus, R. P. J.

    1999-12-01

    Millimeter observations of 48 oxygen- and 20 carbon-rich AGB Miras with periods shorter than 400 days are presented. In addition, observations of 14 O-rich and 15 C-stars with longer, or no known, periods have also been obtained. The detection statistics is as follows: in 12CO J=1-0 and 2-1 we observed 97 stars, and detected 66 in at least one line. We find 24 new detections in the 1-0 line, 38 new detections in the 2-1 line, and 29 stars have been detected for the first time in one or both lines. In 12CO J=3-2 we observed 14 stars and detected 11, with 4 new detections. In 13CO J=2-1, 3-2 we observed 2 stars and had one new detection. In HCN(1-0) we observed 5 carbon stars and detected 3, one new. In SO(6_5-5_4) we observed the same 5 stars and detected none. In CS(3-2) we observed 8 carbon stars and detected 3, all new. In SiO(3-2, v=0) we observed 34 O-rich stars and detected 25, all new except one. Near-infrared JHK photometry is presented for seven stars. For four stars it is the first NIR data published. The luminosity and dust mass loss rate are obtained for seven very red stars with unknown pulsation period from modelling the spectral energy distribution (SED) and IRAS LRS spectra. Thereby, a new IR supergiant is confirmed (AFGL 2968). For the rest of the sample, luminosity and distance are obtained in a variety of ways: using hipparcos parallaxes, period-luminosity and period-M_K-relations combined with apparent K magnitudes, and kinematic distances. The dust mass loss rate is obtained from model fitting of the SED (either from the literature, or presented in the present paper), or from the observed IRAS 60 mu m flux, corrected for the photospheric contribution. The gas mass loss rate is derived from the observed CO line intensities, as presented here, combined with existing literature data, if any. This allows the derivation of the dust-to-gas ratio. Our and literature CO J = 3-2 data has been used to calibrate the relation between mass loss rate and peak

  20. Haemolysis with Björk-Shiley and Starr-Edwards prosthetic heart valves: a comparative study

    PubMed Central

    Slater, S. D.; Sallam, I. A.; Bain, W. H.; Turner, M. A.; Lawrie, T. D. V.

    1974-01-01

    Slater, S. D., Sallam, I. A., Bain, W. H., Turner, M. A., and Lawrie, T. D. V. (1974).Thorax, 29, 624-632. Haemolysis with Björk-Shiley and Starr-Edwards prosthetic heart valves: a comparative study. A comparison was made of the haemolytic complications in 85 patients with two different types of Starr-Edwards cloth-covered ball and cage prosthesis with those in 44 patients with the Björk-Shiley tilting disc valve. Intravascular haemolysis, as detected by the presence of haemosiderinuria, occurred significantly less often with the Björk-Shiley than with the Starr-Edwards valve, the overall incidence with aortic, mitral or multiple replacements being 31%, 15%, and 20% for Björk-Shiley and 94%, 92%, and 88% for Starr-Edwards valves respectively. There was no significant difference in the frequency of haemolysis between each of the two types of Starr-Edwards prosthesis studied at either the aortic (2300 versus 2310 model) or mitral (6300 versus 6310) site. Haemolytic anaemia developed in only one patient with a Björk-Shiley valve but was common though usually mild with Starr-Edwards prostheses, particularly aortic valve replacements with the 2300 model and in aortic plus mitral (± tricuspid) replacements. The greater severity of haemolysis produced by Starr-Edwards valves, again especially of the latter types, was further demonstrated by higher serum lactate dehydrogenase and 24-hour urinary iron levels. It is concluded that the Björk-Shiley tilting disc valve represents a significant advance in the amelioration of the haemolytic complications of prosthetic valves. PMID:4450173

  1. Regional economic impacts of current and proposed management alternatives for Don Edwards National Wildlife Refuge

    USGS Publications Warehouse

    Richardson, Leslie; Huber, Chris; Koontz, Lynne

    2012-01-01

    The National Wildlife Refuge System Improvement Act of 1997 requires all units of the National Wildlife Refuge System to be managed under a Comprehensive Conservation Plan. The Comprehensive Conservation Plan must describe the desired future conditions of a Refuge and provide long-range guidance and management direction to achieve refuge purposes. The Don Edwards San Francisco Bay National Wildlife Refuge, located at the south end of California's San Francisco Bay and one of seven refuges in the San Francisco Bay National Wildlife Refuge Complex, is in the process of developing a range of management goals, objectives, and strategies for the Comprehensive Conservation Plan. The Comprehensive Conservation Plan must contain an analysis of expected effects associated with current and proposed Refuge management strategies. For Refuge Comprehensive Conservation Plan planning, a regional economic analysis provides a means of estimating how current management (No Action Alternative) and proposed management activities (alternatives) affect the local economy. This type of analysis provides two critical pieces of information: (1) it illustrates the Don Edwards San Francisco Bay National Wildlife Refuge's contribution to the local community, and (2) it can help in determining whether economic effects are or are not a real concern in choosing among management alternatives. This report first presents a description of the local community and economy near the Don Edwards San Francisco Bay National Wildlife Refuge. Next, the methods used to conduct a regional economic impact analysis are described. An analysis of the final Comprehensive Conservation Plan management strategies that could affect stakeholders, residents, and the local economy is then presented. The management activities of economic concern in this analysis are: * Spending in the local community by Refuge visitors; * Refuge personnel salary spending; and * Refuge purchases of goods and services within the local

  2. Flood-prone areas and waterways, Edwards Air Force Base, California

    USGS Publications Warehouse

    Meyer, Robert W.; Bowers, James C.

    2002-01-01

    Edwards Air Force Base (EAFB) is in the Mojave Desert region of southern California. Although the climate in the study area is arid, occasional intense storms result in flooding on the base, damaging roads and buildings. To plan for anticipated development at EAFB, the U.S. Department of the Air Force (USAF) and the U.S. Geological Survey (USGS) began a cooperative study to locate flood-prone areas on the base. This report describes flood hazards and shows flood-prone areas of the base.

  3. Science and Technology Review, July-August 1998: Celebrating Edward Teller at 90

    DOE R&D Accomplishments Database

    Smart, J.

    1998-07-01

    On the occasion of Edward Teller's 90th birthday, Science and Technology Review (S&TR) has the pleasure of honoring Lawrence Livermore's co-founder and most influential scientist. Teller is known for his inventive work in physics, his concepts leading to thermonuclear explosions, and his strong stands on such issues as science education, the nation's strategic defense, the needs for science in the future, and sharing scientific information. The articles in this issue also show him, as always, tirelessly moving forward with his new and changing interests.

  4. Getting to grips with the cannabis problem: the evolving contributions and impact of Griffith Edwards.

    PubMed

    Hall, Wayne

    2015-07-01

    Griffith Edwards played an important role in cannabis policy debates within government advisory committees in the United Kingdom from the early 1970s until the early 1980s. This has largely been hidden from public knowledge by the confidentiality of these committee discussions. The purpose of this paper is to use Griffith's writings and the results of recent historical scholarship to outline the views he expressed, the reasons he gave for them, and to provide a brief assessment of his contribution to the development of British cannabis policy. PMID:26042566

  5. Perchlorate in the San Antonio Segment of the Edwards Aquifer, Texas

    NASA Astrophysics Data System (ADS)

    Fahlquist, L.; Rajagapolan, S.; Jackson, W. A.

    2007-12-01

    Perchlorate has been detected in drinking-water supplies and can have adverse health effects on humans by disrupting thyroid function. Perchlorate and other constituents were analyzed from ground-water samples that were collected in 2004-06 from 99 wells completed in the San Antonio segment of the Edwards aquifer as part of the U.S. Geological Survey National Water-Quality Assessment Program. The fractured karstic carbonate Edwards aquifer, declared a sole-source aquifer by the U.S. Environmental Protection Agency, supplies nearly one-half million acre-feet per year for drinking water and other uses. Wells were located in a variety of land-use settings that included rangeland, agriculture, and urban; well types included domestic, public, and observation. Perchlorate was detected in 98 percent of the samples, and concentrations ranged from less than 0.05 to 3 micrograms per liter (μg/L). Five samples contained concentrations greater than 1 μg/L and were from wells in the urban northern San Antonio area. The results from three samples that contained perchlorate at concentrations greater than 2 μg/L are anomalous. Chloride concentration ranged from 5.6 to 69 milligrams per liter, typical for freshwater in the Edwards aquifer. No significant (r2 greater than 0.7) correlations were observed when perchlorate concentrations were correlated with depth to water, total depth of well, or concentrations of bicarbonate, nitrate, phosphate, sulfate, bromide, chloride, fluoride, calcium, magnesium, potassium, sodium, strontium, and dissolved solids. Tritium concentrations ranged from 1.2 to 2.9 tritium units in 31 of the 99 samples and indicate at least some fraction of modern water (post-atmospheric nuclear tests). No correlation between apparent tritium age and perchlorate concentration was observed, a possible indication that anthropogenic influences are not affecting observed perchlorate concentrations. The molar ratio of chloride to perchlorate ranged from 17,000 to 320

  6. Paraprosthetic leak closure 28 years after mitral caged-ball Starr-Edwards implantation.

    PubMed

    Antończyk, Karolina; Paluszkiewicz, Lech; Koertke, Heinrich; Gummert, Jan

    2013-08-01

    In this case report, we present a patient 28 years after mitral valve replacement with the Starr-Edwards prosthesis complicated by periprosthetic leak with severe aortic stenosis and moderate tricuspid regurgitation. We successfully repaired the periprosthetic regurgitation in a patient with extensive mitral annular calcification, without replacement of the valve. No apparent structural deterioration on the caged-ball valve was found. Moreover, aortic valve replacement and tricuspid annuloplasty were performed. One month after reoperation, the patient remained stable with improved clinical status and without any evidence for further paravalvular leak.

  7. Long-term Results of Aortic Valve Replacement with the Starr-Edwards Valve

    PubMed Central

    Fleming, James; Hamer, John; Hayward, Graham; Tubbs, O. S.; Hill, Ian

    1969-01-01

    Review of the 74 patients undergoing aortic valve replacement with a Starr–Edwards ball-valve prosthesis between October 1963 and December 1967 showed that 16 died during surgery or within the first month after operation, usually owing to myocardial failure; and there were nine late deaths. The remaining patients developed few major complications, and the long-term results of operation are considered satisfactory, no patient being grossly incapacitated and most of them are leading active, symptom-free lives. ImagesFig. 1 PMID:5762272

  8. Paraprosthetic leak closure 28 years after mitral caged-ball Starr-Edwards implantation

    PubMed Central

    Antończyk, Karolina; Paluszkiewicz, Lech; Koertke, Heinrich; Gummert, Jan

    2013-01-01

    In this case report, we present a patient 28 years after mitral valve replacement with the Starr-Edwards prosthesis complicated by periprosthetic leak with severe aortic stenosis and moderate tricuspid regurgitation. We successfully repaired the periprosthetic regurgitation in a patient with extensive mitral annular calcification, without replacement of the valve. No apparent structural deterioration on the caged-ball valve was found. Moreover, aortic valve replacement and tricuspid annuloplasty were performed. One month after reoperation, the patient remained stable with improved clinical status and without any evidence for further paravalvular leak. PMID:23599186

  9. STS-36: Breakfast / Suit-Up / C-7 Ex / Launch and Landing at Edwards

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Live footage shows the crew members of STS-36, Commander John O. Creighton, Pilot John H. Casper, and Mission Specialists Richard M. Mullane, David C. Hilmers, and Pierre J. Thuot, having the traditional breakfast, suiting up, and walking out to the Astro-Van. Scenes include panoramic views of the shuttle on the pad, main engine start, ignition, liftoff, and booster separation. The landing of Atlantis at Edwards Air Force Base is also seen. Several playback views from different cameras of both the launch and landing are also presented.

  10. Edward D. Goldberg's proposal of "the Mussel Watch": Reflections after 40years.

    PubMed

    Farrington, John W; Tripp, Bruce W; Tanabe, Shinsuke; Subramanian, Annamalai; Sericano, José L; Wade, Terry L; Knap, Anthony H

    2016-09-15

    We chronicle the extensive influence over the past forty years of Professor Edward D. Goldberg and his call in 1975 for a "Mussel Watch" or bivalve sentinel organism approach to assess geographic status and temporal trends of several chemicals of environmental concern in the coastal ocean. Examples of local, regional, national and international programs are discussed briefly as are examples of interesting useful findings and limitations to the Mussel Watch concept. Mussel Watch continues to provide useful data about status and trends of chemical contamination in coastal ecosystems.

  11. Carbonate geology and hydrology of the Edwards Aquifer in the San Antonio area, Texas

    USGS Publications Warehouse

    Maclay, R.W.; Small, T.A.

    1984-01-01

    Recognition of the hydrostratigraphic subdivisions provides a basis for defining the nonhomogeneity of the aquifer and determining its storage characteristics. The aquifer is considered to be a faulted and multilayered aquifer in which lateral circulation is mainly through very permeable, hydrostratigraphic subdivisions that are hydraulically connected at places by openings associated with steep-angle, normal faults. The Edwards aquifer is vertically displaced for its entire thickness at places along major northeastward trending faults. At these places, ground-water circulation is diverted either southwest or northeast.

  12. STS-29 Discovery, OV-103, lands on Edwards AFB concrete runway 22

    NASA Technical Reports Server (NTRS)

    1989-01-01

    STS-29 Discovery, Orbiter Vehicle (OV) 103, main landing gear (MLG) touches down at a speed of approximately 205 knots (235 miles per hour) on concrete runway 22 at Edwards Air Force Base (AFB), California. Nose landing gear (NLG) is deployed and rides above runway surface prior touchdown. Rear view captures OV-103 as it glides past photographer to wheel stop showing the tail section (speedbrake/rudder) and three space shuttle main engines (SSMEs). Mojave desert scrub brush appears in the foreground with aircraft hangar appearing in the background.

  13. When ecology and sociology meet: the contributions of Edward A. Ross.

    PubMed

    Gross, Matthias

    2002-01-01

    Edward A. Ross, a key figure in the early history of American sociology, developed a conceptualization of natural and social changes of the material environment that is virtually forgotten today. In this paper, these topics are discussed and located vis-à-vis Ross's intellectual contemporaries and their general take on the nature/society relationship. It is argued that ecological and sociological ideas in the early twentieth century influenced one another and, in the case of Ross, produced a perspective of social change that tried to include the dynamics of nature.

  14. Occurrence of the Clover Cyst Nematode, Heterodera trifolii, in Prince Edward Island Soils

    PubMed Central

    Kimpinski, J.; Plumas, G.; MacDonald, M. C.

    1993-01-01

    In a survey of potato and rotational crops on Prince Edward Island, Canada, the cyst stage of the clover cyst nematode, Heterodera trifolii, was found in 43 of 63 sites sampled; however, only 12% of the cysts contained eggs. The root lesion nematode, Pratylenchus penetrans, was the dominant plant parasitic nematode and was found in 56 sites. Extraction of cysts from soil was similar using either the Schuiling centrifuge or the Fenwick can method, although the former was more convenient to use. The modified Baermann funnel method was not efficient for detecting the clover cyst nematode in soil. PMID:19279856

  15. Data on wells in the Edwards Air Force Base area, California

    USGS Publications Warehouse

    Dutcher, L.C.; Bader, J.S.; Hiltgen, W.J.

    1962-01-01

    The data presented In this report were collected by the U.S. Geological Survey as a phase of the investigation of ground-water geology and hydrology of the Edwards Air Force Base area. The study was made in cooperation with the Department of the Air Force but also was coincident with the U.S. Geological Survey investigation of water wells and general hydrologic conditions throughout much of the desert region of southern California. The overall study of general hydrologic conditions in the desert is part of a cooperative program with the California Department of Water Resources.

  16. "Smite this sleeping world awake": Edward Burne-Jones and "The legend of the briar rose".

    PubMed

    Rager, Andrea Wolk

    2009-01-01

    Challenging entrenched preconceptions about the supposed escapism and conservatism of Edward Burne-Jones's art, this paper seeks to establish his monumental painted series, "The Legend of the Briar Rose," as a fundamentally radical and confrontational work. Critics have long viewed it as an endorsement of sleepy stasis, antithetical to the political activism espoused by his friend William Morris. By unraveling the intertwining themes of the series -- the transformative dream vision, artistic labor, the decorative mode, and social egalitarianism -- the "Briar Rose" series is revealed instead to be dramatization of the struggle for personal, social, artistic, and even environmental awakening.

  17. Edwards's statistical mechanics of crumpling networks in crushed self-avoiding sheets with finite bending rigidity

    NASA Astrophysics Data System (ADS)

    Balankin, Alexander S.; Flores-Cano, Leonardo

    2015-03-01

    This paper is devoted to the crumpling of thin matter. The Edwards-like statistical mechanics of crumpling networks in a crushed self-avoiding sheet with finite bending rigidity is developed. The statistical distribution of crease lengths is derived. The relationship between sheet packing density and hydrostatic pressure is established. The entropic contribution to the crumpling network rigidity is outlined. The effects of plastic deformations and sheet self-contacts on crumpling mechanics are discussed. Theoretical predictions are in good agreement with available experimental data and results of numerical simulations. Thus, the findings of this work provide further insight into the physics of crumpling and mechanical properties of crumpled soft matter.

  18. Simulation of groundwater flow in the Edwards-Trinity and related aquifers in the Pecos County region, Texas

    USGS Publications Warehouse

    Thomas, Jonathan V.

    2014-01-01

    The Edwards-Trinity aquifer, a major aquifer in the Pecos County region of western Texas, is a vital groundwater resource for agricultural, industrial, and public supply uses. Resource managers would like to better understand the future availability of water in the Edwards-Trinity aquifer in the Pecos County region and the effects of the possible increase or temporal redistribution of groundwater withdrawals. To that end, the U.S. Geological Survey (USGS), in cooperation with the Middle Pecos Groundwater Conservation District, Pecos County, City of Fort Stockton, Brewster County, and Pecos County Water Control and Improvement District No. 1, completed a comprehensive, integrated analysis of available hydrogeologic data to develop a groundwater-flow model of the Edwards-Trinity and related aquifers in parts of Brewster, Jeff Davis, Pecos, and Reeves Counties. Following calibration, the model was used to evaluate the sustainability of recent (2008) and projected water-use demands on groundwater resources in the study area.

  19. Bentall procedure 39 years after implantation of a Starr-Edwards Aortic Caged- Ball-Valve Prosthesis

    PubMed Central

    2010-01-01

    We report a case of a male patient who received an implantation of a Starr-Edwards-caged-ball-valve-prosthesis in 1967. The surgery and postoperative course were without complications and the patient recovered well after the operation. For the next four decades, the patient remained asymptomatic - no restrictions on his lifestyle and without any complications. In 2006, 39 years after the initial operation, we performed a Bentall-Procedure to treat an aortic ascendens aneurysm with diameters of 6.0 × 6.5 cm: we explanted the old Starr-Edwards-aortic-caged-ball-valve-prosthesis and replaced the ascending aorta with a 29 mm St.Jude Medical aortic-valve-composite-graft and re-implanted the coronary arteries. This case represents the longest time period between Starr-Edwards-caged-ball-valve-prothesis-implantation and Bentall-reoperation, thereby confirming the excellent durability of this valve. PMID:20298579

  20. Bentall procedure 39 years after implantation of a Starr-Edwards aortic caged-ball-valve prosthesis.

    PubMed

    Schmitto, Jan D; Ortmann, Philipp; Popov, Aron F; Coskun, Kasim O; Schotola, Hanna; Friedrich, Martin; Wiese, Christoph H; Sohns, Christian; Mokashi, Suyog A; Didilis, Vassilios N; Schoendube, Friedrich A

    2010-03-18

    We report a case of a male patient who received an implantation of a Starr-Edwards-caged-ball-valve-prosthesis in 1967. The surgery and postoperative course were without complications and the patient recovered well after the operation. For the next four decades, the patient remained asymptomatic--no restrictions on his lifestyle and without any complications. In 2006, 39 years after the initial operation, we performed a Bentall-Procedure to treat an aortic ascendens aneurysm with diameters of 6.0 x 6.5 cm: we explanted the old Starr-Edwards-aortic-caged-ball-valve-prosthesis and replaced the ascending aorta with a 29 mm St.Jude Medical aortic-valve-composite-graft and re-implanted the coronary arteries.This case represents the longest time period between Starr-Edwards-caged-ball-valve-prosthesis-implantation and Bentall-reoperation, thereby confirming the excellent durability of this valve.

  1. New insights into the Edwards Aquifer—Brackish-water simulation, drought, and the role of uncertainty analysis

    USGS Publications Warehouse

    Foster, Linzy K.; White, Jeremy T.

    2016-02-03

    The Edwards aquifer consists of three water-quality zones. The freshwater zone of the Edwards aquifer is bounded to the south by a zone of brackish water (transition zone) where the aquifer transitions from fresh to saline water. The saline zone is downdip from the transition zone. There is concern that a recurrence of extreme drought, such as the 7-year drought from 1950 through 1956, could cause the transition zone to move toward (encroach upon) the freshwater zone, causing production wells near the transition zone to pump saltier water. There is also concern of drought effects on spring flows from Comal and San Marcos Springs. These concerns were evaluated through the development of a new numerical model of the Edwards aquifer.

  2. Bed-material entrainment and associated transportation infrastructure problems in streams of the Edwards Plateau, central Texas

    USGS Publications Warehouse

    Heitmuller, Franklin T.; Asquith, William H.

    2008-01-01

    The Texas Department of Transportation commonly builds and maintains low-water crossings (LWCs) over streams in the Edwards Plateau in Central Texas. LWCs are low-height structures, typically constructed of concrete and asphalt, that provide acceptable passage over seasonal rivers or streams with relatively low normal-depth flow. They are designed to accommodate flow by roadway overtopping during high-flow events. The streams of the Edwards Plateau are characterized by cobble- and gravel-sized bed material and highly variable flow regimes. Low base flows that occur most of the time occasionally are interrupted by severe floods. The floods entrain and transport substantial loads of bed material in the stream channels. As a result, LWCs over streams in the Edwards Plateau are bombarded and abraded by bed material during floods and periodically must be maintained or even replaced.

  3. New insights into the Edwards Aquifer—Brackish-water simulation, drought, and the role of uncertainty analysis

    USGS Publications Warehouse

    Foster, Linzy K.; White, Jeremy T.

    2016-01-01

    The Edwards aquifer consists of three water-quality zones. The freshwater zone of the Edwards aquifer is bounded to the south by a zone of brackish water (transition zone) where the aquifer transitions from fresh to saline water. The saline zone is downdip from the transition zone. There is concern that a recurrence of extreme drought, such as the 7-year drought from 1950 through 1956, could cause the transition zone to move toward (encroach upon) the freshwater zone, causing production wells near the transition zone to pump saltier water. There is also concern of drought effects on spring flows from Comal and San Marcos Springs. These concerns were evaluated through the development of a new numerical model of the Edwards aquifer.

  4. Insects attracted to Maple Sap: Observations from Prince Edward Island, Canada

    PubMed Central

    Majka, Christopher G.

    2010-01-01

    Abstract The collection of maple sap for the production of maple syrup is a large commercial enterprise in Canada and the United States. In Canada, which produces 85% of the world’s supply, it has an annual value of over $168 million CAD. Over 38 million trees are tapped annually, 6.5% of which use traditional buckets for sap collection. These buckets attract significant numbers of insects. Despite this, there has been very little investigation of the scale of this phenomenon and the composition of insects that are attracted to this nutrient source. The present paper reports the results of a preliminary study conducted on Prince Edward Island, Canada. Twenty-eight species of Coleoptera, Lepidoptera, and Trichoptera were found in maple sap buckets, 19 of which are known to be attracted to saps and nectars. The physiological role of sap feeding is discussed with reference to moths of the tribe Xylenini, which are active throughout the winter, and are well documented as species that feed on sap flows. Additionally, 18 of the 28 species found in this study are newly recorded in Prince Edward Island. PMID:21594122

  5. Oil production and groundwater quality in the Edwards-Trinity Plateau Aquifer, Texas.

    PubMed

    Hudak, Paul F

    2003-11-13

    Chloride concentrations and chloride/bromide ratios from 198 water wells in the Edwards-Trinity Plateau Aquifer were compiled, mapped, and evaluated within the context of regional geology and land use. The study area occupies eight counties in west-central Texas, within which oil production and agriculture are predominant land uses. Samples from 49 wells had chloride concentrations above the 250 mg/l secondary drinking water standard, 22 samples had greater than 500 mg/l chloride, and 9 samples exceeded 1000 mg/l chloride. Of the 22 samples above 500 mg/l chloride, 10 had relatively low chloride/bromide ratios of less than 300, consistent with oilfield brine, and 2 had ratios above 2000, consistent with groundwater impacted by evaporite dissolution. The remaining ten samples had chloride/bromide ratios ranging from 300 to 2000, consistent with partial mixing of unimpaired groundwater with evaporite-laden water. There were no significant correlations between chloride concentration and well depth, inconsistent with contaminants originating at the land surface. Results of this study suggest that evaporite dissolution and oilfield brine locally impact the Edwards-Trinity Plateau Aquifer, but the problem is not regionally pervasive.

  6. The Jenner Society and the Edward Jenner Museum: tributes to a physician-scientist.

    PubMed

    Morgan, A J; Poland, Gregory A

    2011-12-30

    Dr. Edward Jenner's discovery and application of vaccination against smallpox was one of the most important medical advances of all time. In the modern era many millions of lives are saved each year by vaccines that work essentially on the same scientific principles established by Jenner more than 200 years ago. Jenner's country home in Berkeley, Gloucestershire, UK, where he carried out his work and where he spent most of his life, is now a museum and something of a shrine for vaccinologists. Jenner's house is also now the focal point of a new international learned society dedicated to advancing modern vaccinology. The aims of the new Jenner Society are to engage, support, and sustain the professional goals of vaccinologists, and to perpetuate the memory of Dr. Edward Jenner. Ultimately it is hoped that the Jenner Society will be recognized as one of the leading academic societies representing and promoting vaccine science around the world. We invite readers to consider joining the society (http://www.edwardjennersociety.org/).

  7. Potential for updip movement of salinewater in the Edwards Aquifer, San Antonio, Texas

    USGS Publications Warehouse

    Perez, Roberto

    1986-01-01

    The model simulations indicate that a large range in the quantity of solute transported from the salinewater zone into the freshwater zone is possible. This uncertainty is caused by the range of estimates of transmissivity, the magnitude of water-level decline, and porosity. Simulated transmissivity values for the Edwards aquifer within the salinewater zone ranged from 134 to 3,340 feet squared per day and resulted in potential lateral shifts of the salinity front from 16 to 425 feet updip into the fresh-water zone at the end of a 10-year simulation. A simulated decline in water levels from an altitude of 660 to 582 feet above sea level resulted in a potential lateral shift in the salinity front of 133 feet updip into the freshwater zone at the end of the 10-year simulation. Simulated porosity values from 1 to 20 percent resulted in lateral shifts of the salinity front from 42 to 854 feet updip into the freshwater zone at the end of the 10-year simulation. An evaluation of the results of the model simulations indicates that contamination created by the movement of saline-water into the freshwater zone of the Edwards aquifer will be limited to an are

  8. Intermediate Term Evaluation of Starr-Edwards Ball Valves in the Mitral Position

    PubMed Central

    Cotrufo, Maurizio; Renzulli, Attilio; Esposito, Vincenzo; Vosa, Carlo; Nappi, Giannantonio; Deluca, Luigi; Casale, Domenico; Bellitti, Renato; Festa, Michele

    1985-01-01

    The Model 6120 ball valve prosthesis introduced in 1965 is still strongly supported as a mitral valve substitute in many centers around the world. A current reassessment of the performance of this prosthesis is therefore pertinent to current medical practice. In this institution since 1974, 227 Starr-Edwards caged ball valves have been implanted in the mitral position during isolated valve replacement. Two models of caged ball valves were used concurrently: the silastic ball valve in 108 patients (48%) and the composite strut “tract” valve in 119 (52%). Hospital mortality was 7%, and 8-year survival (standard error) was 74 (6%), with 100% follow-up, documenting 752 total patient-years. No late deaths were known to be valve related, and there were no cases of prosthetic thrombosis. The actuarial estimate of patients free from thromboembolism at 8 years was 89 (4%) with a linearized rate of 1.3% per year. At the most recent follow-up, 95% of the patients were in the New York Heart Association (NYHA) Classes I or II. These good results were partly due to an awareness at operation of ventricular outflow tract size requirements and to strict control of postoperative anticoagulation. We conclude that the Starr-Edwards ball valve is the mitral valve of choice in the young patient who is able to take anticoagulation drugs and has a left ventricular outflow tract of satisfactory size. PMID:15227040

  9. Ten year clinical evaluation of Starr-Edwards 2400 and 1260 aortic valve prostheses.

    PubMed Central

    Hackett, D; Fessatidis, I; Sapsford, R; Oakley, C

    1987-01-01

    The long term performance characteristics of the 2400 and 1260 series of Starr-Edwards aortic prostheses were investigated by a follow up study of clinical outcome of 327 patients discharged from hospital with isolated aortic valve replacement. Follow up lasted for up to 10 years and was based on 1616 patient-years. The 2400 series cloth covered tracked valve was implanted in 182 patients from 1974 to 1980 and the 1260 series bare strut silastic ball valve was inserted in 145 patients from 1979 to 1983. Total 10 year mortality and valve related morbidity were low and no cases of mechanical valve failure were recorded. There were no significant actuarial differences in mortality or valve related morbidity between the 2400 and 1260 valves. Starr-Edwards models 2400 and 1260 aortic valve prostheses showed excellent durability without any mechanical failures over a 10 year period. The long term outcome of isolated aortic valve replacement with these models is associated with a low frequency of valve related complications. PMID:3580223

  10. The Jenner Society and the Edward Jenner Museum: tributes to a physician-scientist.

    PubMed

    Morgan, A J; Poland, Gregory A

    2011-12-30

    Dr. Edward Jenner's discovery and application of vaccination against smallpox was one of the most important medical advances of all time. In the modern era many millions of lives are saved each year by vaccines that work essentially on the same scientific principles established by Jenner more than 200 years ago. Jenner's country home in Berkeley, Gloucestershire, UK, where he carried out his work and where he spent most of his life, is now a museum and something of a shrine for vaccinologists. Jenner's house is also now the focal point of a new international learned society dedicated to advancing modern vaccinology. The aims of the new Jenner Society are to engage, support, and sustain the professional goals of vaccinologists, and to perpetuate the memory of Dr. Edward Jenner. Ultimately it is hoped that the Jenner Society will be recognized as one of the leading academic societies representing and promoting vaccine science around the world. We invite readers to consider joining the society (http://www.edwardjennersociety.org/). PMID:22486976

  11. Generalized Deam-Edwards approach to the statistical mechanics of randomly crosslinked systems

    NASA Astrophysics Data System (ADS)

    Xing, Xiangjun; Lu, Bing-Sui; Ye, Fangfu; Goldbart, Paul M.

    2013-08-01

    We address the statistical mechanics of randomly and permanently crosslinked networks. We develop a theoretical framework (vulcanization theory) which can be used to systematically analyze the correlation between the statistical properties of random networks and their histories of formation. Generalizing the original idea of Deam and Edwards, we consider an instantaneous crosslinking process, where all crosslinkers (modeled as Gaussian springs) are introduced randomly at once in an equilibrium liquid state, referred to as the preparation state. The probability that two functional sites are crosslinked by a spring exponentially decreases with their distance squared. After formally averaging over network connectivity, we obtained an effective theory with all degrees of freedom replicated 1 + n times. Two thermodynamic ensembles, the preparation ensemble and the measurement ensemble, naturally appear in this theory. The former describes the thermodynamic fluctuations in the state of preparation, while the latter describes the thermodynamic fluctuations in the state of measurement. We classify various correlation functions and discuss their physical significances. In particular, the memory correlation functions characterize how the properties of networks depend on their method of preparation, and are the hallmark properties of all randomly crosslinked materials. We clarify the essential difference between our approach and that of Deam-Edwards, and discuss the saddle-point order parameters and its physical significance. Finally we also discuss the connection between saddle-point approximation of vulcanization theory, and the classical theory of rubber elasticity as well as the neo-classical theory of nematic elastomers.

  12. Rehabilitation of the Rocket Vehicle Integration Test Stand at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    Jones, Daniel S.; Ray, Ronald J.; Phillips, Paul

    2005-01-01

    Since initial use in 1958 for the X-15 rocket-powered research airplane, the Rocket Engine Test Facility has proven essential for testing and servicing rocket-powered vehicles at Edwards Air Force Base. For almost two decades, several successful flight-test programs utilized the capability of this facility. The Department of Defense has recently demonstrated a renewed interest in propulsion technology development with the establishment of the National Aerospace Initiative. More recently, the National Aeronautics and Space Administration is undergoing a transformation to realign the organization, focusing on the Vision for Space Exploration. These initiatives provide a clear indication that a very capable ground-test stand at Edwards Air Force Base will be beneficial to support the testing of future access-to-space vehicles. To meet the demand of full integration testing of rocket-powered vehicles, the NASA Dryden Flight Research Center, the Air Force Flight Test Center, and the Air Force Research Laboratory have combined their resources in an effort to restore and upgrade the original X-15 Rocket Engine Test Facility to become the new Rocket Vehicle Integration Test Stand. This report describes the history of the X-15 Rocket Engine Test Facility, discusses the current status of the facility, and summarizes recent efforts to rehabilitate the facility to support potential access-to-space flight-test programs. A summary of the capabilities of the facility is presented and other important issues are discussed.

  13. Description and Evaluation of Numerical Groundwater Flow Models for the Edwards Aquifer, South-Central Texas

    USGS Publications Warehouse

    Lindgren, Richard J.; Taylor, Charles J.; Houston, Natalie A.

    2009-01-01

    A substantial number of public water system wells in south-central Texas withdraw groundwater from the karstic, highly productive Edwards aquifer. However, the use of numerical groundwater flow models to aid in the delineation of contributing areas for public water system wells in the Edwards aquifer is problematic because of the complex hydrogeologic framework and the presence of conduit-dominated flow paths in the aquifer. The U.S. Geological Survey, in cooperation with the Texas Commission on Environmental Quality, evaluated six published numerical groundwater flow models (all deterministic) that have been developed for the Edwards aquifer San Antonio segment or Barton Springs segment, or both. This report describes the models developed and evaluates each with respect to accessibility and ease of use, range of conditions simulated, accuracy of simulations, agreement with dye-tracer tests, and limitations of the models. These models are (1) GWSIM model of the San Antonio segment, a FORTRAN computer-model code that pre-dates the development of MODFLOW; (2) MODFLOW conduit-flow model of San Antonio and Barton Springs segments; (3) MODFLOW diffuse-flow model of San Antonio and Barton Springs segments; (4) MODFLOW Groundwater Availability Modeling [GAM] model of the Barton Springs segment; (5) MODFLOW recalibrated GAM model of the Barton Springs segment; and (6) MODFLOW-DCM (dual conductivity model) conduit model of the Barton Springs segment. The GWSIM model code is not commercially available, is limited in its application to the San Antonio segment of the Edwards aquifer, and lacks the ability of MODFLOW to easily incorporate newly developed processes and packages to better simulate hydrologic processes. MODFLOW is a widely used and tested code for numerical modeling of groundwater flow, is well documented, and is in the public domain. These attributes make MODFLOW a preferred code with regard to accessibility and ease of use. The MODFLOW conduit-flow model

  14. Hydrogeologic factors that affect the flowpath of water in selected zones of the Edwards Aquifer, San Antonio region, Texas

    USGS Publications Warehouse

    Groschen, G.E.

    1996-01-01

    The Edwards aquifer in the San Antonio region supplies drinking water for more than 1 million people. Proper development and protection of the aquifer is a high priority for local and State authorities. To better understand the flow of water in two major flowpaths in the Edwards aquifer, stratigraphic, structural, hydrologic, and geochemical data were analyzed. The western Medina flowpath is in parts of Uvalde, Medina, and Bexar Counties, and the eastern flowpath is in northern Bexar and central Comal Counties. A major hydrogeologic factor that affects the pattern of flow in the Edwards aquifer is the spatial and temporal distribution of recharge. Other hydrogeologic factors that affect flowpaths include internal boundaries and the location and rate of spring discharge. The relative displacement of faults and the high permeability layers have substantial control on the discharge at springs and on the flowpaths in the Edwards aquifer. Analysis of the estimated recharge to the Edwards aquifer during 1982 89 indicated that during years of substantial precipitation, a large part of the net recharge probably is diffuse infiltration of precipitation over large parts of the recharge area. During years with below-normal precipitation, most recharge is leakage from rivers and streams that drain the catchment subbasins. In the western Medina flowpath, concentrations of major ions indicate saturation of calcite and undersaturation of dolomite the two minerals that constitute most of the Edwards aquifer matrix. Concentrations of dissolved calcium, alkalinity, and dissolved chloride in the eastern flowpath are greater than those in the western Medina flowpath. These upward trends in concentrations might result in part from: (1) increased development in the recharge area, (2) mineralized effluent from developed areas, or (3) increased dissolution of aquifer material. Tritium data from wells sampled in and near the western Medina flowpath indicate no vertical stratification of

  15. Potential for bed-material entrainment in selected streams of the Edwards Plateau - Edwards, Kimble, and Real Counties, Texas, and vicinity

    USGS Publications Warehouse

    Heitmuller, Franklin T.; Asquith, William H.

    2008-01-01

    The Texas Department of Transportation spends considerable money for maintenance and replacement of low-water crossings of streams in the Edwards Plateau in Central Texas as a result of damages caused in part by the transport of cobble- and gravel-sized bed material. An investigation of the problem at low-water crossings was made by the U.S. Geological Survey in cooperation with the Texas Department of Transportation, and in collaboration with Texas Tech University, Lamar University, and the University of Houston. The bed-material entrainment problem for low-water crossings occurs at two spatial scales - watershed scale and channel-reach scale. First, the relative abundance and activity of cobble- and gravel-sized bed material along a given channel reach becomes greater with increasingly steeper watershed slopes. Second, the stresses required to mobilize bed material at a location can be attributed to reach-scale hydraulic factors, including channel geometry and particle size. The frequency of entrainment generally increases with downstream distance, as a result of decreasing particle size and increased flood magnitudes. An average of 1 year occurs between flows that initially entrain bed material as large as the median particle size, and an average of 1.5 years occurs between flows that completely entrain bed material as large as the median particle size. The Froude numbers associated with initial and complete entrainment of bed material up to the median particle size approximately are 0.40 and 0.45, respectively.

  16. Intravascular haemolysis after valve replacement: comparative study between Starr-Edwards (ball valve) and Björk-Shiley (disc valve) prosthesis.

    PubMed Central

    Falk, R H; Mackinnon, J; Wainscoat, J; Melikian, V; Bignell, A H

    1979-01-01

    Seventy-four patients with single prosthetic valves (Björk-Shiley or Starr-Edwards) in the mitral or aortic position and 18 controls with rheumatic valvar heart disease were investigated for evidence of intravascular haemolysis. Serum lactate dehydrogenase (LDH) was used as the most sensitive indicator of haemolysis. Raised concentrations were found in a third of 39 patients with Björk-Shiley prostheses (mean 281 IU/l) and in all 35 patients with Starr-Edwards prostheses (mean 859 IU/l. Values were considerably higher in patients with Starr-Edwards prostheses and particularly in those with aortic prostheses (mean 927 IU/l). Eight out of 12 patients with haemosiderinuria had Starr-Edwards valves. Intravascular haemolysis was of little clinical significance in patients with Björk-Shiley prostheses, but some patients with Starr-Edwards prostheses became iron deficient as a result. PMID:542913

  17. An observational study of dust nucleation in Mira (o Ceti). I. Variable features of AlO and other Al-bearing species

    NASA Astrophysics Data System (ADS)

    Kamiński, T.; Wong, K. T.; Schmidt, M. R.; Müller, H. S. P.; Gottlieb, C. A.; Cherchneff, I.; Menten, K. M.; Keller, D.; Brünken, S.; Winters, J. M.; Patel, N. A.

    2016-07-01

    Context. Dust is efficiently produced by cool giant stars, but the condensation of inorganic dust is poorly understood. Observations of key aluminum bearing molecules around evolved stars has enabled us to investigate the nucleation of alumina (Al2O3) dust in the gas. Aims: We aim to identify and characterize aluminum bearing species in the circumstellar gas of Mira (o Ceti) in order to elucidate their role in the production of Al2O3 dust. Methods: We used multiepoch spectral line observations at (sub-)millimeter, far-infrared, and optical wavelengths including: maps with ALMA that probe the gas distribution in the immediate vicinity of the star at ~30 mas; observations with ALMA, APEX, and Herschel in 2013-2015 for studying cycle and inter-cycle variability of the rotational lines of Al-bearing molecules; optical records as far back as 1965 to examine variations in electronic transitions over time spans of days to decades; and velocity measurements and excitation analysis of the spectral features that constrain the physical parameters of the gas. Results: Three diatomic molecules AlO, AlOH, and AlH, and atomic Al i are the main observable aluminum species in Mira, although a significant fraction of aluminum might reside in other species that have not yet been identified. Strong irregular variability in the (sub-)millimeter and optical features of AlO (possibly the direct precursor of Al2O3) indicates substantial changes in the excitation conditions, or varying abundance that is likely related to shocks in the star. The inhomogeneous distribution of AlO might influence the spatial and temporal characteristics of dust production. Conclusions: We are unable to quantitatively trace aluminum depletion from the gas, but the rich observational material constrains time-dependent chemical networks. Future improvements should include spectroscopic characterization of higher aluminum oxides, coordinated observations of dust and gas species at different variability phases

  18. Linking climate change and karst hydrology to evaluate species vulnerability: The Edwards and Madison aquifers (Invited)

    NASA Astrophysics Data System (ADS)

    Mahler, B. J.; Long, A. J.; Stamm, J. F.; Poteet, M.; Symstad, A.

    2013-12-01

    Karst aquifers present an extreme case of flow along structurally variable pathways, making them highly dynamic systems and therefore likely to respond rapidly to climate change. In turn, many biological communities and ecosystems associated with karst are sensitive to hydrologic changes. We explored how three sites in the Edwards aquifer (Texas) and two sites in the Madison aquifer (South Dakota) might respond to projected climate change from 2011 to 2050. Ecosystems associated with these karst aquifers support federally listed endangered and threatened species and state-listed species of concern, including amphibians, birds, insects, and plants. The vulnerability of selected species associated with projected climate change was assessed. The Advanced Research Weather and Research Forecasting (WRF) model was used to simulate projected climate at a 36-km grid spacing for three weather stations near the study sites, using boundary and initial conditions from the global climate model Community Climate System Model (CCSM3) and an A2 emissions scenario. Daily temperature and precipitation projections from the WRF model were used as input for the hydrologic Rainfall-Response Aquifer and Watershed Flow (RRAWFLOW) model and the Climate Change Vulnerability Index (CCVI) model. RRAWFLOW is a lumped-parameter model that simulates hydrologic response at a single site, combining the responses of quick and slow flow that commonly characterize karst aquifers. CCVI uses historical and projected climate and hydrologic metrics to determine the vulnerability of selected species on the basis of species exposure to climate change, sensitivity to factors associated with climate change, and capacity to adapt to climate change. An upward trend in temperature was projected for 2011-2050 at all three weather stations; there was a trend (downward) in annual precipitation only for the weather station in Texas. A downward trend in mean annual spring flow or groundwater level was projected for

  19. Traditional Native American Ball Games in the Early 20th Century Recorded by Edward S. Curtis, Artist with a Camera.

    ERIC Educational Resources Information Center

    Pesavento, Wilma J.

    The work of Edward S. Curtis, who studied and recorded American Indian culture with a camera, is described in this paper. Curtis recorded on film, with explanatory text, a photo-history of eighty tribes west of the Missouri River. The role of games and their accompanying mythology was one of the salient features of Curtis's work. The general…

  20. The Writing Life: Narrative, Metaphor, and Emotion in the Spiritual Autobiographies of Teresa of Avila and Sarah Edwards

    ERIC Educational Resources Information Center

    Friend, Elizabeth Ford

    2012-01-01

    In this dissertation, I analyze the spiritual autobiographies of Teresa of Avila (1515-1582) and Sarah Edwards (1710-1758) through the methodological lenses of autobiography studies and cognitive linguistics in order to identify key narratives and metaphors for the spiritual life and explore the significance of the interpretation process for lived…

  1. G. Stanley Hall and Edward Thorndike on the Education of Women: Theory and Policy in the Progressive Era.

    ERIC Educational Resources Information Center

    Seller, Maxine S.

    During the Progressive Era (late 19th and early 20th Centuries), the theories of educational psychologists G. Stanley Hall and Edward L. Thorndike provided a basis for educational policy formation. It is hypothesized that their educational policies led to separate and unequal educational programs for women. Review of their writing indicates that…

  2. 77 FR 28895 - Don Edwards San Francisco Bay National Wildlife Refuge, Alameda, Santa Clara, and San Mateo...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ...We, the U.S. Fish and Wildlife Service (Service) announce the availability of a Draft Comprehensive Conservation Plan (CCP) and Environmental Assessment (EA) for the Don Edwards San Francisco Bay National Wildlife Refuge for public review and comment. The CCP/EA, prepared under the National Wildlife Refuge System Improvement Act of 1997, and in accordance with the National Environmental Policy......

  3. Map Showing Geology and Hydrostratigraphy of the Edwards Aquifer Catchment Area, Northern Bexar County, South-Central Texas

    USGS Publications Warehouse

    Clark, Amy R.; Blome, Charles D.; Faith, Jason R.

    2009-01-01

    Rock units forming the Edwards and Trinity aquifers in northern Bexar County, Texas, are exposed within all or parts of seven 7.5-minute quadrangles: Bulverde, Camp Bullis, Castle Hills, Helotes, Jack Mountain, San Geronimo, and Van Raub. The Edwards aquifer is the most prolific ground-water source in Bexar County, whereas the Trinity aquifer supplies water for residential, commercial, and industrial uses for areas north of the San Antonio. The geologic map of northern Bexar County shows the distribution of informal hydrostratigraphic members of the Edwards Group and the underlying upper member of the Glen Rose Limestone. Exposures of the Glen Rose Limestone, which forms the Trinity aquifer alone, cover approximately 467 km2 in the county. This study also describes and names five informal hydrostratigraphic members that constitute the upper member of the Glen Rose Limestone; these include, in descending order, the Caverness, Camp Bullis, Upper evaporite, Fossiliferous, and Lower evaporite members. This study improves our understanding of the hydrogeologic connection between the two aquifers as it describes the geology that controls the infiltration of surface water and subsurface flow of ground water from the catchment area (outcropping Trinity aquifer rocks) to the Edwards water-bearing exposures.

  4. Native Agency and the Making of "The North American Indian": Alexander B. Upshaw and Edward S. Curtis

    ERIC Educational Resources Information Center

    Zamir, Shamoon

    2007-01-01

    The twenty volumes of ethnographic text and pictorial photography and the twenty portfolios of large, finely printed photogravures that together comprise "The North American Indian" were the product of an extraordinary labor by Edward S. Curtis, an extensive and shifting team of co-workers, and the participation of hundreds of Native Americans. By…

  5. Missions and Medicine at Amherst: Family Ties to Edward Hitchcock Jr., the Missionary Movement, and the American University of Beirut

    ERIC Educational Resources Information Center

    Dorman, John M.

    2011-01-01

    The Haystack Movement began at Williams College in 1805, occasioning the spread of American missions throughout the world. A half century later, two graduates of nearby Amherst College, Edward Hitchcock Jr. and Daniel Bliss, laid the foundations for college health services in this country and for mission work and education in the Middle East. The…

  6. Edward Miner Gallaudet's "Remarks on the Combined System": An Analysis of the "Preservative" Function of Rhetoric of Education.

    ERIC Educational Resources Information Center

    Sharkey, William F.; Hikins, James W.

    1993-01-01

    Examines Edward Miner Gallaudet's speech, "Remarks on the Combined System," to illustrate the power of the rhetorical knowledge thesis to account for paradoxes in Gallaudet's discourse on educating the deaf student. Contends that Gallaudet offered his remarks to preserve his ideas for a later age when they might receive sympathetic treatment. (SR)

  7. Edward D. Churchill as a combat consultant: lessons for the senior visiting surgeons and today's military medical corps.

    PubMed

    Cannon, Jeremy W; Fischer, Josef E

    2010-03-01

    In World War II, Edward D. Churchill volunteered as a combat consultant. In this role, he mentored many junior surgeons and challenged the Army leadership to treat hemorrhagic shock with blood rather than plasma. These lessons have continued relevance for today's Senior Visiting Surgeons and our military medical corps.

  8. Learning the Way: Teaching and Learning with and for Youth from Refugee Backgrounds on Prince Edward Island

    ERIC Educational Resources Information Center

    MacNevin, Joanne

    2012-01-01

    This article presents one component of a qualitative study that explored teaching and learning with and for youth from refugee backgrounds in Prince Edward Island (PEI) intermediate and high schools. Specifically, this article presents data and discussion regarding some of the challenges and professional development needs of teachers working with…

  9. Sediment yield dynamics during the 1950s multi-year droughts from two ungauged basins in the Edwards Plateau, Texas

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sediment yield dynamics on the Edwards Plateau region of Texas was dramatically influenced by a multi-year drought that occurred there during the 1950s. To assess the effect of this drought on sediment yield, we used the Soil and Water Assessment Tool (SWAT) to identify the factors that contributed...

  10. Three-dimensional geologic framework modeling of faulted hydrostratigraphic units within the Edwards Aquifer, Northern Bexar County, Texas

    USGS Publications Warehouse

    Pantea, Michael P.; Cole, James C.

    2004-01-01

    This report describes a digital, three-dimensional faulted hydrostratigraphic model constructed to represent the geologic framework of the Edwards aquifer system in the area of San Antonio, northern Bexar County, Texas. The model is based on mapped geologic relationships that reflect the complex structures of the Balcones fault zone, detailed lithologic descriptions and interpretations of about 40 principal wells (and qualified data from numerous other wells), and a conceptual model of the gross geometry of the Edwards Group units derived from prior interpretations of depositional environments and paleogeography. The digital model depicts the complicated intersections of numerous major and minor faults in the subsurface, as well as their individual and collective impacts on the continuity of the aquifer-forming units of the Edwards Group and the Georgetown Formation. The model allows for detailed examination of the extent of fault dislocation from place to place, and thus the extent to which the effective cross-sectional area of the aquifer is reduced by faulting. The model also depicts the internal hydrostratigraphic subdivisions of the Edwards aquifer, consisting of three major and eight subsidiary hydrogeologic units. This geologic framework model is useful for visualizing the geologic structures within the Balcones fault zone and the interactions of en-echelon fault strands and flexed connecting fault-relay ramps. The model also aids in visualizing the lateral connections between hydrostratigraphic units of relatively high and low permeability across the fault strands. Introduction The Edwards aquifer is the principal source of water for municipal, agricultural, industrial, and military uses by nearly 1.5 million inhabitants of the greater San Antonio, Texas, region (Hovorka and others, 1996; Sharp and Banner, 1997). Discharges from the Edwards aquifer also support local recreation and tourism industries at Barton, Comal, and San Marcos Springs located

  11. Edward Meryon (1807-80) and Charles Darwin's (1809-82) On the Origin of Species.

    PubMed

    Emery, Alan E H; Emery, Marcia L H

    2009-11-01

    London in the first half of the 19th century was a centre of scientific and medical interest. For example, the Royal Society, the Linnean Society, the Geological Society, the Chemical Society and the Royal Astronomical Society were all centred on Burlington House and, not far away, in Berner's Street was the Medical and Chirurgical Society, which in 1834 became the Royal Medical and Chirurgical Society and later the Royal Society of Medicine. It was also in this period that Edward Meryon became a member of the latter society and subsequently a Council Member, Librarian and Vice-President. His research led to the clear identification for the first time of the disease Duchenne muscular dystrophy and he published his results in the Transactions of the Royal Medical and Chirurgical Society in 1852. PMID:20029074

  12. Sonic booms of space shuttles approaching Edwards Air Force Base, 1988-1993.

    PubMed

    Young, Robert W

    2002-01-01

    From 1988 to 1993 13 sonic booms of space shuttles approaching Edwards Air Force Base were measured at a site 10 miles west of EAFB, with one to seven different sound level meters for each measurement. Results from five of these measurements are here presented. Maximum differences in measured levels between instruments for the same flight varied from 0 to 6 dB depending on the measurement descriptor and model of sound level meter. The average difference between predicted and measured values was 0.7+/-1.5 dB. For sound level meters with adequate bandwidth the waveforms measured varied from a near perfect N-wave to a more distorted form reflecting the influence of the varying condition of the atmosphere during propagation to the ground. PMID:11837962

  13. Edward Leicester Atkinson (1881-1929): Antarctic explorer, scientist and naval surgeon.

    PubMed

    Guly, Henry

    2016-02-01

    Edward Leicester Atkinson qualified at St Thomas's Hospital in 1906 and joined the Navy in 1908. He was a doctor and parasitologist on Captain Scott's Terra Nova expedition to the Antarctic and had to take charge of the expedition when Scott died on his return from the South Pole. After the expedition he went to China and discovered the cause of schistosomiasis, returning at the start of the First World War in which he served with distinction, winning a DSO and Albert Medal but also being severely injured. After the war he served in various naval posts and became the youngest Surgeon Captain in the Navy before being retired on health grounds in 1928. He died at sea the following year.

  14. Mary Edwards Walker, M.D.: a feminist physician a century ahead of her time.

    PubMed

    Spiegel, A D; Suskind, P B

    1996-06-01

    In her teens, Mary Edwards Walker already wore the "bloomer" outfit began to campaign for reforming the "unhygienic" clothing of women. Assertively, she attended medical school and earned her M.D. degree. Due to prejudice, her practice did not flourish and she moved to Washington to offer her medical services to the Union as the Civil War began. Rebuffed by the male medical bureaucrats, she volunteered her services anyway. Eventually, she was awarded the Congressional Medal of Honor, the only women to ever gain such distinction. After the war, Walker became a journalist, an author of two sensational books, a political lobbyist, a suffrage campaigner, a professional and public lecturer, an ardent dress reformer, a peace activist, a Utopianist and a women's right advocate. Light-years ahead of her times, Dr. Walker was an intelligent, independent, irrepressible and indefatigable proponent for a host of worthy causes.

  15. John L. LaBrecque Receives 2013 Edward A. Flinn III Award: Response

    NASA Astrophysics Data System (ADS)

    LaBrecque, John L.

    2014-01-01

    Thank you, Jean Bernard Minster and those who supported my nomination for the Edward A. Flinn III Award. We owe so much to colleagues such as Bernard Minster who support NASA and Earth Science with unrelenting and unselfish service. I am also grateful to my parents, the people of Lewiston, Maine, and the National Defense Education Act (NDEA) of 1958 for nurturing my early interest in science with an education that ultimately led me to Columbia University and the Lamont-Doherty Earth Observatory. Lamont for me was a scientific wonderland tended by scientists with global appetites for discovery and adventure. Marine geophysics, geomagnetism, and satellite altimetry of the oceans were creating a revolution of discovery, and Lamont was the center of this revolution. I owe so much to my mentor and dear friend, Walter C. Pitman III, who showed me that great science was accomplished through boundless curiosity, perseverance, and, most of all, humility.

  16. A review of Edward Flatau's 1894 Atlas of the Human Brain by the neurologist Sigmund Freud.

    PubMed

    Triarhou, Lazaros C

    2011-01-01

    In 1894, the Polish neurologist Edward Flatau (1868-1932), working in Berlin, published an exquisite photographic atlas of the unfixed human brain, preceding by 2 years Das Menschenhirn, the reference work of Gustaf Retzius (1842-1919) in Stockholm. In his early career as a neuroanatomist and neurologist, Sigmund Freud (1856-1939) wrote a review of Flatau's atlas for the Internationale klinische Rundschau, which has not been included in the 'Standard Edition of the Complete Psychological Works'. The aim of the present paper is twofold: to document Freud's review, and to revive the largely forgotten atlas of Flatau. The full text of Freud is presented in translation. Further, one element Flatau, Retzius and Freud had in common is discussed: their early role as protagonists and firm supporters of Ramón y Cajal's neuron theory, the cornerstone of modern neuroscience.

  17. Sir Edward Mellanby (1884-1955) GBE KCB FRCP FRS: nutrition scientist and medical research mandarin.

    PubMed

    Hawgood, Barbara J

    2010-08-01

    Edward Mellanby used the experimental method to investigate medical problems. In 1918, working at King's College for Women, London, he provided conclusive evidence that rickets is a dietary deficiency disease due to lack of a fat-soluble vitamin [D]. In Sheffield he demonstrated that cereals, in an unbalanced diet, produced rickets due to the phytic acid content reducing the availability of calcium. Mellanby became Secretary of the Medical Research Council (1933-49) but continued his research by working at weekends. In the 1930s he campaigned for the results of nutritional research to be used for the benefit of public health. During World War II he acted as a scientific adviser to the War Cabinet and had a strong influence on the food policy which maintained successfully the nutrition of the population during the shipping blockade. Mellanby was a formidable person but with sagacity he promoted new research and guided the expansion of the organization.

  18. A Gentleman's mad-doctor in Georgian England: Edward Long Fox and Brislington House.

    PubMed

    Smith, Leonard

    2008-06-01

    The late eighteenth and early nineteenth centuries were a period of particular innovation in the history of British psychiatry. Enlightenment ideas brought a change in attitudes to insanity, reflected in the growing prevalence of psychologically based treatment techniques being implemented in both public and private institutions. A new group of practitioners, specializing in the treatment and management of insanity, was emerging. One of the most prominent and successful was Dr. Edward Long Fox, a Bristol physician. His main venture was the establishment of Brislington House in 1806. Here he created a state-of-the-art asylum, catering mainly for the wealthier members of society. Its unique design, with seven distinct houses, enabled classification of patients according to social class as well as behavioural presentation. Within a context of safety and security, Fox sought to provide a therapeutic regime based on the principles and practices of moral management.

  19. Sir Edward Appleton and Joseph Priestley: two giants of electrical science

    NASA Astrophysics Data System (ADS)

    Excell, P. S.

    The life of Sir Edward Appleton is reviewed, in commemoration of the recent centenary of his birth. Appleton discovered the ionosphere and devoted much of his life to investigations of its properties, receiving the Nobel Prize for physics as a result. He became a senior government scientist in World War II and afterwards was appointed Vice-Chancellor of Edinburgh University. The influence of his roots in the city of Bradford is emphasized and compared with the case of Joseph Priestley, also born near Bradford some 160 yr earlier. Priestley was a major early investigator of electrical phenomena and compiled a comprehensive treatise on the electrical knowledge of his day. He was the first person to present an experimental proof of the inverse-square law of electrostatic force, although he is usually better remembered as the discoverer of oxygen.

  20. Disc wear and entrapment in a Starr-Edwards mitral caged-disc valve.

    PubMed

    Aoyagi, Shigeaki; Fukunaga, Shuji; Arinaga, Koichi

    2011-07-01

    A case of wear and entrapment of a polyethylene disc observed in a Starr-Edwards (SE) mitral caged-disc valve at 37 years after implantation is reported. A 66-year-old woman who had undergone mitral valve replacement with a SE disc valve 37 years previously was admitted to the authors' hospital. Cinefluoroscopy showed the polyethylene disc of the SE valve to have impinged against a calcified mass on the left ventricular posterior wall, causing a tipping motion of the disc during opening. The valve was successfully replaced at surgery. A macroscopic examination of the excised valve revealed wear of the polyethylene disc at sites where the disc abutted the cage struts, and where it impinged on the calcified mass. The long-term durability of the SE caged-disc valves has been favorable; however, when implanted for over 20 years, they should be carefully followed up.

  1. Late results of aortic valve replacement with the Starr-Edwards prosthesis.

    PubMed Central

    Morgans, C M; Barritt, D W; Belsey, R H; Keen, G; Wensley, R

    1970-01-01

    Details are presented concerning 59 patients who left hospital between January 1964 and January 1969 after aortic valve replacement with the Starr-Edwards prosthesis. Of the 14 late deaths, 7 are known to have been due to causes related to the prosthesis and 4 to other causes. The 45 surviving patients have nearly all shown clinical improvement and only 3 are unable to work as a result of some complication of the operation. Aortic regurgitation and its consequences appear to be the most significant factor leading to symptoms. In 11 of 16 patients with anaemia there was evidence of intravascular haemolysis. The long-term consequence of this complication is not known. Images PMID:5212355

  2. Estimating transmissivity in the Edwards Aquifer using upscaling, geostatistics, and Bayesian updating

    NASA Astrophysics Data System (ADS)

    Painter, S. L.; Jiang, Y.; Woodbury, A. D.

    2002-12-01

    The Edwards Aquifer, a highly heterogeneous karst aquifer located in south central Texas, is the sole source of drinking water for more than one million people. Hydraulic conductivity (K) measurements in the Edwards Aquifer are sparse, highly variable (log-K variance of 6.4), and are mostly from single-well drawdown tests that are appropriate for the spatial scale of a few meters. To support ongoing efforts to develop a groundwater management (MODFLOW) model of the San Antonio segment of the Edwards Aquifer, a multistep procedure was developed to assign hydraulic parameters to the 402 m x 402 m computational cells intended for the management model. The approach used a combination of nonparametric geostatistical analysis, stochastic simulation, numerical upscaling, and automatic model calibration based on Bayesian updating [1,2]. Indicator correlograms reveal a nested spatial structure in the well-test K of the confined zone, with practical correlation ranges of 3,600 and 15,000 meters and a large nugget effect. The fitted geostatistical model was used in unconditional stochastic simulations by the sequential indicator simulation method. The resulting realizations of K, defined at the scale of the well tests, were then numerically upscaled to the block scale. A new geostatistical model was fitted to the upscaled values. The upscaled model was then used to cokrige the block-scale K based on the well-test K. The resulting K map was then converted to transmissivity (T) using deterministically mapped aquifer thickness. When tested in a forward groundwater model, the upscaled T reproduced hydraulic heads better than a simple kriging of the well-test values (mean error of -3.9 meter and mean-absolute-error of 12 meters, as compared with -13 and 17 meters for the simple kriging). As the final step in the study, the upscaled T map was used as the prior distribution in an inverse procedure based on Bayesian updating [1,2]. When input to the forward groundwater model, the

  3. 'Spinal amaurosis' (1841). On the early contribution of Edward Hocken to the concept of neuromyelitis optica.

    PubMed

    Jarius, S; Wildemann, B

    2014-02-01

    While the history of classical multiple sclerosis has been extensively studied, only little is known about the early history of neuromyelitis optica (Devic's syndrome). Here we discuss a forgotten report by Edward Octavius Hocken (1820-1845) published in The Lancet in 1841. Hocken's report is important from a historic point of view for two reasons. Firstly, apart from a French language report by Antoine Portal, no earlier case of spinal cord inflammation and amaurosis is known. Secondly and much more importantly, Hocken, who upon his untimely death at the age of just 25 years was honoured by his contemporaries as a "precocious talent" of "very early reputation", in that article propagated the novel concept of 'spinal amaurosis', i.e. the concept of acute amaurosis and spinal cord disease being pathogenetically connected. Hocken's ideas predate Devic and Gault's seminal works on 'neuromyelitis optica' by more than 50 years.

  4. Edward Meryon (1807-80) and Charles Darwin's (1809-82) On the Origin of Species.

    PubMed

    Emery, Alan E H; Emery, Marcia L H

    2009-11-01

    London in the first half of the 19th century was a centre of scientific and medical interest. For example, the Royal Society, the Linnean Society, the Geological Society, the Chemical Society and the Royal Astronomical Society were all centred on Burlington House and, not far away, in Berner's Street was the Medical and Chirurgical Society, which in 1834 became the Royal Medical and Chirurgical Society and later the Royal Society of Medicine. It was also in this period that Edward Meryon became a member of the latter society and subsequently a Council Member, Librarian and Vice-President. His research led to the clear identification for the first time of the disease Duchenne muscular dystrophy and he published his results in the Transactions of the Royal Medical and Chirurgical Society in 1852.

  5. The Elegance of Disordered Granular Packings: A Validation of Edwards' Hypothesis

    NASA Technical Reports Server (NTRS)

    Metzger, Philip T.; Donahue, Carly M.

    2004-01-01

    We have found a way to analyze Edwards' density of states for static granular packings in the special case of round, rigid, frictionless grains assuming constant coordination number. It obtains the most entropic density of single grain states, which predicts several observables including the distribution of contact forces. We compare these results against empirical data obtained in dynamic simulations of granular packings. The agreement between theory and the empirics is quite good, helping validate the use of statistical mechanics methods in granular physics. The differences between theory and empirics are mainly due to the variable coordination number, and when the empirical data are sorted by that number we obtain several insights that suggest an underlying elegance in the density of states

  6. Mary Edwards Walker, M.D.: a feminist physician a century ahead of her time.

    PubMed

    Spiegel, A D; Suskind, P B

    1996-06-01

    In her teens, Mary Edwards Walker already wore the "bloomer" outfit began to campaign for reforming the "unhygienic" clothing of women. Assertively, she attended medical school and earned her M.D. degree. Due to prejudice, her practice did not flourish and she moved to Washington to offer her medical services to the Union as the Civil War began. Rebuffed by the male medical bureaucrats, she volunteered her services anyway. Eventually, she was awarded the Congressional Medal of Honor, the only women to ever gain such distinction. After the war, Walker became a journalist, an author of two sensational books, a political lobbyist, a suffrage campaigner, a professional and public lecturer, an ardent dress reformer, a peace activist, a Utopianist and a women's right advocate. Light-years ahead of her times, Dr. Walker was an intelligent, independent, irrepressible and indefatigable proponent for a host of worthy causes. PMID:8726211

  7. 'Spinal amaurosis' (1841). On the early contribution of Edward Hocken to the concept of neuromyelitis optica.

    PubMed

    Jarius, S; Wildemann, B

    2014-02-01

    While the history of classical multiple sclerosis has been extensively studied, only little is known about the early history of neuromyelitis optica (Devic's syndrome). Here we discuss a forgotten report by Edward Octavius Hocken (1820-1845) published in The Lancet in 1841. Hocken's report is important from a historic point of view for two reasons. Firstly, apart from a French language report by Antoine Portal, no earlier case of spinal cord inflammation and amaurosis is known. Secondly and much more importantly, Hocken, who upon his untimely death at the age of just 25 years was honoured by his contemporaries as a "precocious talent" of "very early reputation", in that article propagated the novel concept of 'spinal amaurosis', i.e. the concept of acute amaurosis and spinal cord disease being pathogenetically connected. Hocken's ideas predate Devic and Gault's seminal works on 'neuromyelitis optica' by more than 50 years. PMID:24366649

  8. Using Edward de Bono's six hats game to aid critical thinking and reflection in palliative care.

    PubMed

    Kenny, Lesley J

    2003-03-01

    This article describes the use of a creative thinking game to stimulate critical thinking and reflection with qualified health professionals undertaking palliative care education. The importance of reflective practice in nursing is well documented and numerous models are available. However, the author as a nurse teacher has found that many of these models are either too simple or too complex to be valuable in practice. The six hats game, devised by Edward de Bono, is a method that stimulates a variety of types of thinking and when used as a means of reflection helps students to become more critical about their practice. Using this game with a palliative care case study the author demonstrates how thinking more creatively about the patients' perceived needs and problems can assist in developing reflective skills. The article concludes with a discussion on some of the challenges of using this method and suggestions for future practical uses. PMID:12682572

  9. Using Edward de Bono's six hats game to aid critical thinking and reflection in palliative care.

    PubMed

    Kenny, Lesley J

    2003-03-01

    This article describes the use of a creative thinking game to stimulate critical thinking and reflection with qualified health professionals undertaking palliative care education. The importance of reflective practice in nursing is well documented and numerous models are available. However, the author as a nurse teacher has found that many of these models are either too simple or too complex to be valuable in practice. The six hats game, devised by Edward de Bono, is a method that stimulates a variety of types of thinking and when used as a means of reflection helps students to become more critical about their practice. Using this game with a palliative care case study the author demonstrates how thinking more creatively about the patients' perceived needs and problems can assist in developing reflective skills. The article concludes with a discussion on some of the challenges of using this method and suggestions for future practical uses.

  10. Sonic booms of space shuttles approaching Edwards Air Force Base, 1988-1993.

    PubMed

    Young, Robert W

    2002-01-01

    From 1988 to 1993 13 sonic booms of space shuttles approaching Edwards Air Force Base were measured at a site 10 miles west of EAFB, with one to seven different sound level meters for each measurement. Results from five of these measurements are here presented. Maximum differences in measured levels between instruments for the same flight varied from 0 to 6 dB depending on the measurement descriptor and model of sound level meter. The average difference between predicted and measured values was 0.7+/-1.5 dB. For sound level meters with adequate bandwidth the waveforms measured varied from a near perfect N-wave to a more distorted form reflecting the influence of the varying condition of the atmosphere during propagation to the ground.

  11. Sawfly taxa (Hymenoptera, Symphyta) described by Edward Newman and Charles Healy

    PubMed Central

    Liston, Andrew D.; Prous, Marko

    2014-01-01

    Abstract Type specimens of seven nominal species of sawfly described by Edward Newman and one by Charles Healy were studied. This material is housed in the Oxford University Museum of Natural History, United Kingdom. The following new synonymies are proposed (valid names in parentheses): Hartigia Schiødte, 1839 (Phylloecus Newman, 1838), Cephus helleri Taschenberg, 1871 (Phylloecus faunus Newman, 1838) and Euura gallae Newman, 1837 (Euura mucronata (Hartig, 1837)). The type species of Euura Newman, 1837 and Euura subgenus Gemmura E. L. Smith, 1968 belong to the same taxonomic species, Euura mucronata (Hartig, 1837), so that these genus group names become new synonyms. Lectotypes are designated for Phyllotoma tormentillae Healy, 1868, Fenusa ianthe Newman, 1837, Fenusa parviceps Newman, 1837, Selandria pallida Newman, 1837 and Phylloecus faunus Newman, 1838. 26 new combinations are proposed for species formerly placed in Hartigia and here transferred to Phylloecus, and 4 original combinations are re-instated as valid. PMID:24715803

  12. Source, variability, and transformation of nitrate in a regional karst aquifer: Edwards aquifer, central Texas.

    PubMed

    Musgrove, M; Opsahl, S P; Mahler, B J; Herrington, C; Sample, T L; Banta, J R

    2016-10-15

    Many karst regions are undergoing rapid population growth and expansion of urban land accompanied by increases in wastewater generation and changing patterns of nitrate (NO3(-)) loading to surface and groundwater. We investigate variability and sources of NO3(-) in a regional karst aquifer system, the Edwards aquifer of central Texas. Samples from streams recharging the aquifer, groundwater wells, and springs were collected during 2008-12 from the Barton Springs and San Antonio segments of the Edwards aquifer and analyzed for nitrogen (N) species concentrations and NO3(-) stable isotopes (δ(15)N and δ(18)O). These data were augmented by historical data collected from 1937 to 2007. NO3(-) concentrations and discharge data indicate that short-term variability (days to months) in groundwater NO3(-) concentrations in the Barton Springs segment is controlled by occurrence of individual storms and multi-annual wet-dry cycles, whereas the lack of short-term variability in groundwater in the San Antonio segment indicates the dominance of transport along regional flow paths. In both segments, longer-term increases (years to decades) in NO3(-) concentrations cannot be attributed to hydrologic conditions; rather, isotopic ratios and land-use change indicate that septic systems and land application of treated wastewater might be the source of increased loading of NO3(-). These results highlight the vulnerability of karst aquifers to NO3(-) contamination from urban wastewater. An analysis of N-species loading in recharge and discharge for the Barton Springs segment during 2008-10 indicates an overall mass balance in total N, but recharge contains higher concentrations of organic N and lower concentrations of NO3(-) than does discharge, consistent with nitrification of organic N within the aquifer and consumption of dissolved oxygen. This study demonstrates that subaqueous nitrification of organic N in the aquifer, as opposed to in soils, might be a previously unrecognized

  13. Infectious disease survey of Rio Grande wild turkeys in the Edwards Plateau of Texas.

    PubMed

    Peterson, Markus J; Aguirre, Raymond; Ferro, Pamela J; Jones, Dustin A; Lawyer, Tim A; Peterson, M Nils; Silvy, Nova J

    2002-10-01

    State wildlife agencies have translocated thousands of wild turkeys (Meleagris gallopavo) since the 1930s to reestablish this species. Because of threats to the domestic poultry industry and wild birds, screening for selected infectious agents has become routine since the early 1980s. One of the principal sources for Rio Grande wild turkeys (M. gallopavo intermedia) for translocation purposes was the Edwards Plateau of Texas (USA). Unfortunately, turkey abundance has declined in the southern Edwards Plateau since the late 1970s. Surprisingly few studies have addressed wild turkeys in this region, perhaps reflecting its status as the heart of Rio Grande turkey range. We surveyed 70 free-living Rio Grande wild turkeys from Bandera and Kerr counties, Texas, for evidence of exposure to Salmonella typhimurium, S. pullorum, Mycoplasma gallisepticum, M. meleagridis, M. synoviae, Chlamydophila psittaci, and the avian influenza, Newcastle disease, turkey corona, and reticuloendotheliosis viruses. Of these, 80% (56) were seropositive for both M. gallisepticum and M. synoviae on the serum plate antigen test. Ten of these individuals (14% of total) were positive for M. synoviae by hemagglutination inhibition testing. All other serologic tests were negative. Two adult females sampled in Kerr County, whose body mass was significantly less than that of other adult females trapped in the area, tested positive for reticuloendotheliosis virus (REV) proviral DNA on polymerase chain reaction. Reticuloendotheliosis virus was isolated from one of these individuals. The pathogenesis, transmission, and/or population-level influences of M. gallisepticum, M. synoviae, and REV in Rio Grande wild turkeys deserves further study.

  14. Source, variability, and transformation of nitrate in a regional karst aquifer: Edwards aquifer, central Texas.

    PubMed

    Musgrove, M; Opsahl, S P; Mahler, B J; Herrington, C; Sample, T L; Banta, J R

    2016-10-15

    Many karst regions are undergoing rapid population growth and expansion of urban land accompanied by increases in wastewater generation and changing patterns of nitrate (NO3(-)) loading to surface and groundwater. We investigate variability and sources of NO3(-) in a regional karst aquifer system, the Edwards aquifer of central Texas. Samples from streams recharging the aquifer, groundwater wells, and springs were collected during 2008-12 from the Barton Springs and San Antonio segments of the Edwards aquifer and analyzed for nitrogen (N) species concentrations and NO3(-) stable isotopes (δ(15)N and δ(18)O). These data were augmented by historical data collected from 1937 to 2007. NO3(-) concentrations and discharge data indicate that short-term variability (days to months) in groundwater NO3(-) concentrations in the Barton Springs segment is controlled by occurrence of individual storms and multi-annual wet-dry cycles, whereas the lack of short-term variability in groundwater in the San Antonio segment indicates the dominance of transport along regional flow paths. In both segments, longer-term increases (years to decades) in NO3(-) concentrations cannot be attributed to hydrologic conditions; rather, isotopic ratios and land-use change indicate that septic systems and land application of treated wastewater might be the source of increased loading of NO3(-). These results highlight the vulnerability of karst aquifers to NO3(-) contamination from urban wastewater. An analysis of N-species loading in recharge and discharge for the Barton Springs segment during 2008-10 indicates an overall mass balance in total N, but recharge contains higher concentrations of organic N and lower concentrations of NO3(-) than does discharge, consistent with nitrification of organic N within the aquifer and consumption of dissolved oxygen. This study demonstrates that subaqueous nitrification of organic N in the aquifer, as opposed to in soils, might be a previously unrecognized

  15. Valve Replacement with the Starr-Edwards and Hancock Prostheses: Comparative Analysis of Late Morbidity and Mortality

    PubMed Central

    Oyer, Philip E.; Stinson, Edward B.; Griepp, Randall B.; Shumway, Norman E.

    1977-01-01

    Although the Starr-Edwards caged-ball valve remains a standard of comparison for more recently introduced prostheses, a substantial incidence of thromboembolic and hemorrhagic complications prompted our evaluation of the Hancock glutaraldehyde-fixed porcine xenograft. We have compared the results of 435 aortic valve replacements using the Starr- Edwards valve (SE-AVR), 515 mitral valve replacements (SE-MVR), and 121 double-valve replacements (SE-AVRMVR) with 251 aortic valve replacements using the xenograft aortic valve (X-AVR), 338 mitral valve replacements (X-MVR), and 88 double-valve replacements (X-AVR-MVR). The Starr- Edwards valves were used during the period 1963 through 1973 and the xenograft valves between 1971 and 1976. No significant differences in patient age, sex, or preoperative hemodynamic data were noted between comparable groups. All patients with Starr-Edwards valves received long-term anticoagulation while anticoagulants were used only for specific indications in patients with xenograft valves. Total follow up was 3944 patient years for the Starr-Edwards patients and 947 patient years for the xenograft patients. Hospital mortality was not significantly different for comparable groups: SE-AVR 6.9% vs. X-AVR 6.4%, SE-MVR 9.7% vs X-MVR 8.6%, and SE-AVR-MVR 7.5% vs. X-AVR-MVR 10.2%. Linearized mortality and morbidity data expressed as percent per patient- year are tabulated below. Pairs which differ significantly (p < .05) are italicized. PMID:560824

  16. Groundwater ages from the freshwater zone of the Edwards aquifer, Uvalde County, Texas—Insights into groundwater flow and recharge

    USGS Publications Warehouse

    Hunt, Andrew G.; Landis, Gary P.; Faith, Jason R.

    2016-02-23

    Tritium–helium-3 groundwater ages of the Edwards aquifer in south-central Texas were determined as part of a long-term study of groundwater flow and recharge in the Edwards and Trinity aquifers. These ages help to define groundwater residence times and to provide constraints for calibration of groundwater flow models. A suite of 17 samples from public and private supply wells within Uvalde County were collected for active and noble gases, and for tritium–helium-3 analyses from the confined and unconfined parts of the Edwards aquifer. Samples were collected from monitoring wells at discrete depths in open boreholes as well as from integrated pumped well-head samples. The data indicate a fairly uniform groundwater flow system within an otherwise structurally complex geologic environment comprised of regionally and locally faulted rock units, igneous intrusions, and karst features within carbonate rocks. Apparent ages show moderate, downward average, linear velocities in the Uvalde area with increasing age to the east along a regional groundwater flow path. Though the apparent age data show a fairly consistent distribution across the study area, many apparent ages indicate mixing of both modern (less than 60 years) and premodern (greater than 60 years) waters. This mixing is most evident along the “bad water” line, an arbitrary delineation of 1,000 milligrams per liter dissolved solids that separates the freshwater zone of the Edwards aquifer from the downdip saline water zone. Mixing of modern and premodern waters also is indicated within the unconfined zone of the aquifer by high excess helium concentrations in young waters. Excess helium anomalies in the unconfined aquifer are consistent with possible subsurface discharge of premodern groundwater from the underlying Trinity aquifer into the younger groundwater of the Edwards aquifer.

  17. Riverbed-Sediment Mapping in the Edwards Dam Impoundment on the Kennebec River, Maine By Use of Geophysical Techniques

    USGS Publications Warehouse

    Dudley, Robert W.

    1999-01-01

    INTRODUCTION In July 1997, the Federal Energy Regulatory Commission (FERC) issued a Final Environmental Impact Statement recommending that the 162-year-old Edwards Dam on the Kennebec River in Augusta, Maine, be removed. The impoundment formed by Edwards Dam extends about 15 mi to the city of Waterville, near the confluence of the Sebasticook River with the Kennebec River. The impoundment has a surface area of 1,143 acres, a gross storage of approximately 740 million ft3, and a usable storage of about 184 million ft3 (Stone and Webster, 1995a). According to FERC, removal of the 917-ft-long, 24-ft-high timber crib and concrete structure would restore 15 mi of riverine habitat, improve passage of ocean-migrating fish species native to the Kennebec River, and result in substantial recreational enhancements (Federal Energy Regulatory Commission, 1997). Because the removal of Edwards Dam would change the hydraulic characteristics of the river in the present-day impoundment, the potential transport of erodible, fine-grained sediment currently in the impoundment is a concern. Of particular concern is the erosion and transport of this sediment to areas downstream from the dam, a process that could introduce possible bacterial and chemical contamination and could impede river navigation as a result of sediment deposition. In an effort to build upon available information on the composition of the riverbed, the U.S. Geological Survey (USGS), in cooperation with the Maine State Planning Office, classified riverbed sediment types and mapped their areal extents in the lower (southern) half of the Edwards Dam impoundment. This report describes the methods used to collect and analyze the data used to create a map of sediment types in the Edwards Dam impoundment. The map is included with this report. Data used to map riverbed sediment types were also used to estimate the volume of observed mud and mud-containing sediment in the study area.

  18. Groundwater ages from the freshwater zone of the Edwards aquifer, Uvalde County, Texas—Insights into groundwater flow and recharge

    USGS Publications Warehouse

    Hunt, Andrew G.; Landis, Gary P.; Faith, Jason R.

    2016-01-01

    Tritium–helium-3 groundwater ages of the Edwards aquifer in south-central Texas were determined as part of a long-term study of groundwater flow and recharge in the Edwards and Trinity aquifers. These ages help to define groundwater residence times and to provide constraints for calibration of groundwater flow models. A suite of 17 samples from public and private supply wells within Uvalde County were collected for active and noble gases, and for tritium–helium-3 analyses from the confined and unconfined parts of the Edwards aquifer. Samples were collected from monitoring wells at discrete depths in open boreholes as well as from integrated pumped well-head samples. The data indicate a fairly uniform groundwater flow system within an otherwise structurally complex geologic environment comprised of regionally and locally faulted rock units, igneous intrusions, and karst features within carbonate rocks. Apparent ages show moderate, downward average, linear velocities in the Uvalde area with increasing age to the east along a regional groundwater flow path. Though the apparent age data show a fairly consistent distribution across the study area, many apparent ages indicate mixing of both modern (less than 60 years) and premodern (greater than 60 years) waters. This mixing is most evident along the “bad water” line, an arbitrary delineation of 1,000 milligrams per liter dissolved solids that separates the freshwater zone of the Edwards aquifer from the downdip saline water zone. Mixing of modern and premodern waters also is indicated within the unconfined zone of the aquifer by high excess helium concentrations in young waters. Excess helium anomalies in the unconfined aquifer are consistent with possible subsurface discharge of premodern groundwater from the underlying Trinity aquifer into the younger groundwater of the Edwards aquifer.

  19. Curved butterfly bileaflet prosthetic cardiac valve

    DOEpatents

    McQueen, David M.; Peskin, Charles S.

    1991-06-25

    An annular valve body having a central passageway for the flow of blood therethrough with two curved leaflets each of which is pivotally supported on an accentric positioned axis in the central passageway for moving between a closed position and an open position. The leaflets are curved in a plane normal to the eccentric axis and positioned with the convex side of the leaflets facing each other when the leaflets are in the open position. Various parameters such as the curvature of the leaflets, the location of the eccentric axis, and the maximum opening angle of the leaflets are optimized according to the following performance criteria: maximize the minimum peak velocity through the valve, maximize the net stroke volume, and minimize the mean forward pressure difference, thereby reducing thrombosis and improving the hemodynamic performance.

  20. X-43A Undergoing Controlled Radio Frequency Testing in the Benefield Anechoic Facility at Edwards Ai

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The X-43A Hypersonic Experimental (Hyper-X) Vehicle hangs suspended in the cavernous Benefield Aenechoic Facility at Edwards Air Force Base during radio frequency tests in January 2000. Hyper-X, the flight vehicle for which is designated as X-43A, is an experimental flight-research program seeking to demonstrate airframe-integrated, 'air-breathing' engine technologies that promise to increase payload capacity for future vehicles, including hypersonic aircraft (faster than Mach 5) and reusable space launchers. This multiyear program is currently underway at NASA Dryden Flight Research Center, Edwards, California. The Hyper-X schedule calls for its first flight later this year (2000). Hyper-X is a joint program, with Dryden sharing responsibility with NASA's Langley Research Center, Hampton, Virginia. Dryden's primary role is to fly three unpiloted X-43A research vehicles to validate engine technologies and hypersonic design tools as well as the hypersonic test facility at Langley. Langley manages the program and leads the technology development effort. The Hyper-X Program seeks to significantly expand the speed boundaries of air-breathing propulsion by being the first aircraft to demonstrate an airframe-integrated, scramjet-powered free flight. Scramjets (supersonic-combustion ramjets) are ramjet engines in which the airflow through the whole engine remains supersonic. Scramjet technology is challenging because only limited testing can be performed in ground facilities. Long duration, full-scale testing requires flight research. Scramjet engines are air-breathing, capturing their oxygen from the atmosphere. Current spacecraft, such as the Space Shuttle, are rocket powered, so they must carry both fuel and oxygen for propulsion. Scramjet technology-based vehicles need to carry only fuel. By eliminating the need to carry oxygen, future hypersonic vehicles will be able to carry heavier payloads. Another unique aspect of the X-43A vehicle is the airframe integration

  1. Source, variability, and transformation of nitrate in a regional karst aquifer: Edwards aquifer, central Texas.

    USGS Publications Warehouse

    Musgrove, Marylynn; Opsahl, Stephen P.; Mahler, Barbara J.; Herrington, Chris; Sample, Thomas; Banta, John (Ryan)

    2016-01-01

    Many karst regions are undergoing rapid population growth and expansion of urban land accompanied by increases in wastewater generation and changing patterns of nitrate (NO3−) loading to surface and groundwater. We investigate variability and sources of NO3− in a regional karst aquifer system, the Edwards aquifer of central Texas. Samples from streams recharging the aquifer, groundwater wells, and springs were collected during 2008–12 from the Barton Springs and San Antonio segments of the Edwards aquifer and analyzed for nitrogen (N) species concentrations and NO3− stable isotopes (δ15N and δ18O). These data were augmented by historical data collected from 1937 to 2007. NO3− concentrations and discharge data indicate that short-term variability (days to months) in groundwater NO3− concentrations in the Barton Springs segment is controlled by occurrence of individual storms and multi-annual wet-dry cycles, whereas the lack of short-term variability in groundwater in the San Antonio segment indicates the dominance of transport along regional flow paths. In both segments, longer-term increases (years to decades) in NO3− concentrations cannot be attributed to hydrologic conditions; rather, isotopic ratios and land-use change indicate that septic systems and land application of treated wastewater might be the source of increased loading of NO3−. These results highlight the vulnerability of karst aquifers to NO3− contamination from urban wastewater. An analysis of N-species loading in recharge and discharge for the Barton Springs segment during 2008–10 indicates an overall mass balance in total N, but recharge contains higher concentrations of organic N and lower concentrations of NO3−than does discharge, consistent with nitrification of organic N within the aquifer and consumption of dissolved oxygen. This study demonstrates that subaqueous nitrification of organic N in the aquifer, as opposed to in soils, might be a previously

  2. The structure and function of roots of woody species on the Edwards Plateau, Texas, USA

    NASA Astrophysics Data System (ADS)

    Pockman, W. T.; McElrone, A. J.; Bleby, T. M.; Jackson, R. B.

    2008-05-01

    The Edwards Plateau in central Texas USA, supports woody vegetation in savannas and woodlands despite characteristically shallow soils. Surveys using caves to access greater depths have shown that roots of all dominant woody species can reach 7 m below the surface while some species reliably reach depths as great as 20 m. Comparative studies showed that deep roots were structurally distinct from shallow roots of similar diameter. Deep roots had larger xylem conducting elements resulting in more than 2-fold greater hydraulic conductance than their shallow counterparts. To understand the relationship between environmental fluctuations and deep root function in these species, we directly measured water transport in deep roots accessed via caves for comparison with similar measurements in shallow roots and stems. Long term measurements of Juniperus ashei, one of the most abundant species on the Edwards plateau, showed that the contribution of roots 7 m below the surface fluctuated with the volumetric water content (VWC) of surface soils. During prolonged drought, upward flow in deep roots accounted for as much as 60% of total daily transpiration and occurred not only during the day when the canopy was transpiring but also throughout the night when hydraulic redistribution from deep to shallow soil maintained flow through the roots. Hydraulic redistribution was suppressed immediately after precipitation until nocturnal flow gradually increased as VWC decreased. In a cave system where roots reach a stream 18-20 m below the surface, hydraulic redistribution was observed year-round in all measured individuals of three additional dominant species (Quercus fusiformis, Bumelia lanuginosa and Prosopis glandulosa). Like J. ashei, upward hydraulic redistribution was observed when surface soils were dry. More complex patterns of redistribution were also observed, including downward redistribution of soil water following precipitation, and continuing redistribution of soil water

  3. Effects of altered soil moisture on respiratory quotient in the Edwards Plateau

    NASA Astrophysics Data System (ADS)

    Sellers, M. A.; Hawkes, C.; Breecker, D.

    2014-12-01

    Climate change is expected to alter precipitation patterns around the world. The impacts of altered precipitation on ecosystem function will be partly controlled by soil microbes because of their primary role in soil carbon cycling. However, microbial responses to drought remain poorly understood, particularly local responses that might partly reflect specialization based on historical conditions. Here, we investigated the respiratory response of microbial communities originating from historically wetter and drier sites to both low and high soil moistures. We focused on the respiratory quotient (RQ= moles of CO2 produced per mole of O2 consumed), which varies with the oxidation state of organic carbon being respired and/or the compounds being synthesized by soil microbes. We hypothesized that there would be a shift in RQ across the gradient of soil moisture. Soils were collected from 13 sites across a steep precipitation gradient on the Edwards plateau in central Texas, air-dried, rewet at low or high soil moisture (6% or 24% gravimetric, respectively), and incubated in an atmosphere of 21% O2, 1% Ar, and balance He. After eight weeks, CO2, O2 and Ar in the headspace of incubation vials were measured by gas chromatography after separation of Ar and O2 at subambient temperature. Because of the high calcite content in soils on the Edwards plateau, we corrected the RQ values by assuming pH was buffered at 8 and then adding the calculated amount of CO2 dissolved in water in the incubations vials to the measured CO2 in the headspace. We found that uncorrected RQ values were slightly less than one and increased significantly with increasing mean annual precipitation. In contrast, corrected RQ values were greater than one and decreased with increasing mean annual precipitation. In both cases, we see a shift in RQ across the gradient, suggesting that differences in substrate utilization may vary based on origin across the gradient and with current level of soil moisture

  4. Longitudinal distribution and lateral pattern of megalopal settlement and juvenile recruitment of Carcinus maenas (L.) (Brachyura, Portunidae) in the Mira River Estuary, Portugal

    NASA Astrophysics Data System (ADS)

    Silva, Inês C.; Dinis, Ana M.; Francisco, Sara M.; Flores, Augusto A. V.; Paula, José

    2006-08-01

    Settlement is a critical process in the life history of crabs, and thus affecting the abundance, distribution and structure of estuarine communities. The spatial pattern of settlement of megalopae of the shore crab Carcinus maenas along a longitudinal estuarine gradient (Mira River Estuary, Portugal) was examined, as well as its effects on the juvenile population. To measure megalopal settlement, four replicate collectors were deployed in six equally spaced stations along the estuarine axis. Juveniles were collected on the same locations with a quadrat randomly deployed on the substrate. To assess fine-scale megalopal settlement within a curved region of the estuary, replicate collectors were deployed on both margins along Moinho da Asneira curve. Megalopae settled differently along the six longitudinal points, with a tendency to attenuate their settlement upstream. Within the curved region, megalopae preferentially settled on the left margin collectors, probably due to the weaker velocity speeds felt on this margin. Concerning the overall juvenile density, there were significant differences among the stations distributed along the estuary, but they did no reflect a longitudinal dispersion attenuation pattern. Size-frequency distribution of the juvenile population showed that the average size is higher on the left margin. Recruits (carapace length between 1.0 mm and 3.4 mm) were more abundant on the upstream stations. Density of early juveniles (3.4 mm-6.5 mm) and juveniles (6.5 mm-10 mm) was more stable throughout the estuary axis than that of recruits. This distribution pattern may result from tidal excursion processes or mechanisms to avoid biotic interactions, such as predation and competition.

  5. Edward A. Delgado-Romero: Award for Distinguished Early Career Contributions to Psychology in the Public Interest.

    PubMed

    2011-11-01

    Presents Edward A. Delgado-Romero, the 2011 winner of the American Psychological Association Award for Distinguished Early Career Contributions to Psychology in the Public Interest. "Societies, professions, and individual citizens are enriched by the contributions of those who care. Edward A. Delgado-Romero has demonstrated through his scholarship, leadership in psychological associations such as the National Latina/Latino Psychological Association, and collaborations with universities and school districts in Georgia that he cares and is committed to addressing challenges in the provision of culturally sensitive psychological services to benefit the public interest. His example of servant leadership leaves a legacy to other early career professionals and graduate students alike. Es un hijo honorado." (PsycINFO Database Record (c) 2011 APA, all rights reserved).

  6. Historical saturated thickness of the Edwards-Trinity aquifer system and selected contiguous hydraulically connected units, west-central Texas

    USGS Publications Warehouse

    Ardis, Ann F.; Barker, Rene A.

    1993-01-01

    The purposes of this report are to illustrate the historical distribution of saturated thickness (hereafter referred to as the saturated thickness) in the Edwards-Trinity aquifer system, summarize the reasons for the variation in the saturated thickness, and relate the regional effects of this variation to the distribution of transmissivity. The saturated thickness map (sheet 2) was determined for most of the area by subtracting the altitude of the base of the aquifer system (Barker and Ardis, 1992) from the altitude of the historical potentiometric surface (Bush and others, 1993). Where the Edwards and Trinity aquifers are confined in the Balcones fault zone, the saturated thickness is defined by the thickness of the aquifer system, which was determined by subtracting the altitude of the base of the aquifer system from the altitude of the base of the Navarro-Del Rio confining unit (G.E. Groschen and W.G. Stein, U.S. Geological Survey, written commun, 1990).

  7. Thrombo-embolic complications of the cloth-covered Starr-Edwards prostheses No. 2300 aortic and No. 6300 mitral

    PubMed Central

    Cleland, J.; Molloy, P. J.

    1973-01-01

    The thrombo-embolic complications of the cloth-covered Starr-Edwards prostheses No. 2300 aortic and No. 6300 mitral followed for an average of 14 months in 155 patients are reviewed. There was a high incidence of early fatal and disabling thrombo-embolus in patients having mitral valve replacement. Late emboli were more common after aortic valve replacement. Anticoagulant control was unsatisfactory and not without hazards. PMID:4685210

  8. Investigation of seismicity and related effects at NASA Ames-Dryden Flight Research Facility, Computer Center, Edwards, California

    NASA Technical Reports Server (NTRS)

    Cousineau, R. D.; Crook, R., Jr.; Leeds, D. J.

    1985-01-01

    This report discusses a geological and seismological investigation of the NASA Ames-Dryden Flight Research Facility site at Edwards, California. Results are presented as seismic design criteria, with design values of the pertinent ground motion parameters, probability of recurrence, and recommended analogous time-history accelerograms with their corresponding spectra. The recommendations apply specifically to the Dryden site and should not be extrapolated to other sites with varying foundation and geologic conditions or different seismic environments.

  9. The Interdisciplinary Generalist Curriculum Project at Joan C. Edwards School of Medicine at Marshall University.

    PubMed

    Veitia, M; McCarty, S; Kelly, P; Szarek, J; Harvey, H

    2001-04-01

    The Interdisciplinary Generalist Curriculum (IGC) Project was designed to enhance interest in and support of generalism during the first two years of medical education. The original goals at Joan C. Edwards School of Medicine at Marshall University included the design and implementation of a core curriculum, Introduction to Patient Care (IPC), and enhancement of teaching excellence through faculty development. The core curriculum facilitated integration with the basic sciences and early introduction of physical examination skills, which were further developed in longitudinal clinical experiences with mentors. Although it was not originally intended to include basic scientists in the preceptor groups, they became important additions and created additional opportunities for interdisciplinary teaching and reciprocal learning. The mentor program, another well-received and intended curriculum change, evolved from a structured experience to a more flexible component of the curriculum. The program met the requirements of the IGC Project but 53% of the originally intended mentor time was achievable, due to curriculum constraints. Faculty development, another success, was originally intended to target IPC faculty but ultimately became a university-wide effort. The changes implemented as a result of the IGC Project continue to flourish beyond the funding period and have become integral aspects of the curriculum and the medical school.

  10. A survey of biological productivity of Prince Edward Island swine herds.

    PubMed Central

    Van Til, L D; Dohoo, I R; Spangler, E; Ogilvie, T H

    1991-01-01

    Sow and feeder pig productivity were measured on a random sample of 32 Prince Edward Island swine farms (each producing over 1000 market hogs per year). Productivity parameters could be arranged in a hierarchy, with the highest level on farrow-finish operations represented by pigs weaned per sow per year. The 17 farrow-finish farms in this study averaged 19.6 (+/- 2.2 SD) pigs weaned per sow per year. Large variation between farms was observed with a range from 16.2 to 24.9 pigs weaned per sow per year. The major opportunities for improving productivity, as compared to reviewed targets, lie in reducing the average weaning age, reducing preweaning mortality, and reducing non-productive sow days per parity. The 14 feeder operations were characterized by 0.58 +/- 0.07 kg average daily gain. Average daily gain was negatively correlated with mortality (r = -0.662, p = 0.010), suggesting that herds that achieved a high rate of gain also had lower mortality. PMID:1884298

  11. Editorial - Climate change impacts on rural poverty in low-elevation coastal zones, Edward B. Barbier

    NASA Astrophysics Data System (ADS)

    Elliott, Michael; Wolanski, Eric

    2015-11-01

    In the Invited Feature Article in this issue of Estuarine, Coastal and Shelf Science, we are extremely grateful to Edward Barbier for performing the major task of increasing our awareness of the hazards and risks faced by all communities on low lying coasts but especially the poor, rural communities (Barbier, 2015). Against a background of climate-induced change, we now have a good and increasing evidence of the way the natural estuarine, coastal and marine system will respond (Elliott et al, 2015). However, more importantly Barbier (2015) highlights the way in which poor, rural coastal communities will be affected and will need to respond or will need help from the developed world to respond. It is axiomatic that while those communities are having less impact than more developed countries on the causes of climate change they are more affected and so have to respond to its consequences, what have been called exogenic unmanaged pressures. Hence they need to rely on mechanisms, techniques, technologies and approaches to help them cope with such change (see also Wolanski and Elliott 2015).

  12. Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures.

    PubMed

    Amano, Tomokazu; Jeffries, Emiko; Amano, Misa; Ko, Akihiro C; Yu, Hong; Ko, Minoru S H

    2015-10-01

    Aneuploidy, an abnormal number of chromosomes, has previously been considered irremediable. Here, we report findings that euploid cells increased among cultured aneuploid cells after exposure to the protein ZSCAN4, encoded by a mammalian-specific gene that is ordinarily expressed in preimplantation embryos and occasionally in stem cells. For footprint-free delivery of ZSCAN4 to cells, we developed ZSCAN4 synthetic mRNAs and Sendai virus vectors that encode human ZSCAN4. Applying the ZSCAN4 biologics to established cultures of mouse embryonic stem cells, most of which had become aneuploid and polyploid, dramatically increased the number of euploid cells within a few days. We then tested the biologics on non-immortalized primary human fibroblast cells derived from four individuals with Down syndrome—the most frequent autosomal trisomy of chromosome 21. Within weeks after ZSCAN4 application to the cells in culture, fluorescent in situ hybridization with a chromosome 21-specific probe detected the emergence of up to 24% of cells with only two rather than three copies. High-resolution G-banded chromosomes further showed up to 40% of cells with a normal karyotype. These findings were confirmed by whole-exome sequencing. Similar results were obtained for cells with the trisomy 18 of Edwards syndrome. Thus a direct, efficient correction of aneuploidy in human fibroblast cells seems possible in vitro using human ZSCAN4. PMID:26324424

  13. Optical scattering simulation of ice particles with surface roughness modeled using the Edwards-Wilkinson equation

    NASA Astrophysics Data System (ADS)

    Zhang, Jianing; Bi, Lei; Liu, Jianping; Panetta, R. Lee; Yang, Ping; Kattawar, George W.

    2016-07-01

    Constructing an appropriate particle morphology model is essential for realistic simulation of optical properties of atmospheric particles. This paper presents a model for generating surface roughness based on a combination of methods from discrete differential geometry combined with a stochastic partial differential equation for surface evolution introduced by Edwards and Wilkinson. Scattering of light by roughened particles is simulated using the Invariant Imbedding T-Matrix (II-TM) method. The effects of surface roughness on the single-scattering properties, namely, the phase matrix, asymmetry factor, and extinction efficiency, are investigated for a single wavelength in the visible range and for a range of size parameters up to x=50. Three different smooth shapes are considered: spherical, spheroidal, and hexagonal, the latter two in just the "compact particle" case of unit aspect ratio. It is shown that roughness has negligible effects on the optical scattering properties for size parameters less than 20. For size parameters ranging from 20 to 50, the phase matrix elements are more sensitive to the surface roughness than are two important integral optical properties, the extinction efficiency and asymmetry factor. As has been seen in studies using other forms of roughening, the phase function is progressively smoothed as roughness increases. The effect on extinction efficiency is to increase it, and on asymmetry factor is to decrease it. Each of these effects is relatively modest in the size range considered, but the trend of results suggests that greater effects will be seen for size parameters larger than ones considered here.

  14. [Peter Plett and other discoverers of cowpox vaccination before Edward Jenner].

    PubMed

    Plett, Peter C

    2006-01-01

    Before Edward Jenner tested the possibility of using the cowpox vaccine as an immunisation for smallpox in humans in 1796, at least six people had done the same several years earlier. However, the findings of these six people regarding the cowpox vaccination are either hardly known or have even been forgotten. For the first time, the originally scattered information on the procedures used by these six people has been gathered and will be presented in this article. Detailed attention will be given to the works of the teacher Peter Plett (1766-1823), the only one to recognize the importance of his discovery for mankind. In 1790 and 1791/92, Plett reported his findings to the Medical Faculty of the University of Kiel. The faculty disregarded Plett's reports by neither responding to them nor changing their methods of immunisation, as the faculty at that time was still in favour of variolation. This article contains the available information and references concerning Plett's discovery, including the entire sources from 1802 and 1815 describing his findings.

  15. Effects of trichloroethylene and perchloroethylene on wild rodents at Edwards Air Force Base, California, USA.

    PubMed

    Spring, Sarah E; Miles, A Keith; Anderson, Michael J

    2004-09-01

    Effects of inhalation of volatilized trichloroethylene (TCE) or perchloroethylene (PCE) were assessed based on the health and population size of wild, burrowing mammals at Edwards Air Force Base (CA, USA). Organic soil-vapor concentrations were measured at three sites with aquifer contamination of TCE or PCE of 5.5 to 77 mg/L and at two uncontaminated reference sites. Population estimates of kangaroo rats (Dipodomys merriami and D. panamintinus) as well as hematology, blood chemistry, and histopathology of kangaroo rats and deer mice (Peromyscus maniculatus) were compared between contaminated and uncontaminated populations. Maximum soil-gas concentrations associated with groundwater contamination were less than 1.5 microl/L of TCE and 0.07 microl/L of PCE. Population estimates of kangaroo rats were similar at contaminated and reference sites. Hematology, blood chemistry, and histopathology of kangaroo rats and deer mice indicated no evidence of health effects caused by exposure. Trichloroethylene or PCE in groundwater and in related soil gas did not appear to reduce the size of small mammal populations or impair the health of individuals.

  16. Statistical Short-Range Guidance for Peak Wind Speed Forecasts at Edwards Air Force Base, CA

    NASA Technical Reports Server (NTRS)

    Dreher, Joseph G.; Crawford, Winifred; Lafosse, Richard; Hoeth, Brian; Burns, Kerry

    2009-01-01

    The peak winds near the surface are an important forecast element for space shuttle landings. As defined in the Flight Rules (FR), there are peak wind thresholds that cannot be exceeded in order to ensure the safety of the shuttle during landing operations. The National Weather Service Spaceflight Meteorology Group (SMG) is responsible for weather forecasts for all shuttle landings, and is required to issue surface average and 10-minute peak wind speed forecasts. They indicate peak winds are a challenging parameter to forecast. To alleviate the difficulty in making such wind forecasts, the Applied Meteorology Unit (AMU) developed a PC-based graphical user interface (GUI) for displaying peak wind climatology and probabilities of exceeding peak wind thresholds for the Shuttle Landing Facility (SLF) at Kennedy Space Center (KSC; Lambert 2003). However, the shuttle occasionally may land at Edwards Air Force Base (EAFB) in southern California when weather conditions at KSC in Florida are not acceptable, so SMG forecasters requested a similar tool be developed for EAFB.

  17. Phase diagram and reentrance for the 3D Edwards-Anderson model using information theory

    NASA Astrophysics Data System (ADS)

    Cortez, V.; Saravia, G.; Vogel, E. E.

    2014-12-01

    Data compressor techniques are used to study the phase diagram of the generalized Edwards-Anderson model in three dimensions covering the full range of mixture between ferromagnetic (concentration 1-x) and antiferromagnetic interactions (concentration x). The recently proposed data compressor wlzip is used to recognize criticality by the maximum information content in the files storing the simulation processes. The method allows not only the characterization of the ferromagnetic to paramagnetic (FP) transition (x<0.22, or x>0.78) but also it equally well yields the spin-glass to paramagnetic (SP) transition (0.22

  18. A premature obituary: Edward C. Spitzka and the American psychiatry of 1878.

    PubMed

    Geller, Jeffrey

    2011-09-01

    On March 4, 1878, at a meeting of the New York Neurological Society, Edward C. Spitzka delivers a blistering attack on psychiatry, basically dismissing all alienists as incompetent and indicating that "the study of insanity should be considered a subdivision of neurology." This address was published in the Journal of Nervous and Mental Disease in 1878 and reproduced in the current issue of the journal.Spitzka asserts that "nothing worthy of notice has proceeded from our insane asylums" and that asylum superintendents may be experts in many things, but they are not experts in the "diagnosis, pathology, and treatment of insanity." To ascertain whether or not Spitzka's characterizations were correct, I examined the medical and psychiatric literature published in English only in 1878.This review indicates that Spitzka was largely wrong. Research was not what it should have been, and the alienists (psychiatrists of that era) knew it. American alienists, however, were otherwise engaged in all manner of deliberations about important issues of the day relevant to the practice of psychiatry. In fact, to an absolutely remarkable degree, the issues of 1878 are the same as those of American psychiatry in the 21st century. That might say much more about psychiatry than Spitzka could ever have known 133 years ago.

  19. Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures

    PubMed Central

    Amano, Tomokazu; Jeffries, Emiko; Amano, Misa; Ko, Akihiro C.; Yu, Hong; Ko, Minoru S. H.

    2015-01-01

    Aneuploidy, an abnormal number of chromosomes, has previously been considered irremediable. Here, we report findings that euploid cells increased among cultured aneuploid cells after exposure to the protein ZSCAN4, encoded by a mammalian-specific gene that is ordinarily expressed in preimplantation embryos and occasionally in stem cells. For footprint-free delivery of ZSCAN4 to cells, we developed ZSCAN4 synthetic mRNAs and Sendai virus vectors that encode human ZSCAN4. Applying the ZSCAN4 biologics to established cultures of mouse embryonic stem cells, most of which had become aneuploid and polyploid, dramatically increased the number of euploid cells within a few days. We then tested the biologics on non-immortalized primary human fibroblast cells derived from four individuals with Down syndrome—the most frequent autosomal trisomy of chromosome 21. Within weeks after ZSCAN4 application to the cells in culture, fluorescent in situ hybridization with a chromosome 21-specific probe detected the emergence of up to 24% of cells with only two rather than three copies. High-resolution G-banded chromosomes further showed up to 40% of cells with a normal karyotype. These findings were confirmed by whole-exome sequencing. Similar results were obtained for cells with the trisomy 18 of Edwards syndrome. Thus a direct, efficient correction of aneuploidy in human fibroblast cells seems possible in vitro using human ZSCAN4. PMID:26324424

  20. [Peter Plett and other discoverers of cowpox vaccination before Edward Jenner].

    PubMed

    Plett, Peter C

    2006-01-01

    Before Edward Jenner tested the possibility of using the cowpox vaccine as an immunisation for smallpox in humans in 1796, at least six people had done the same several years earlier. However, the findings of these six people regarding the cowpox vaccination are either hardly known or have even been forgotten. For the first time, the originally scattered information on the procedures used by these six people has been gathered and will be presented in this article. Detailed attention will be given to the works of the teacher Peter Plett (1766-1823), the only one to recognize the importance of his discovery for mankind. In 1790 and 1791/92, Plett reported his findings to the Medical Faculty of the University of Kiel. The faculty disregarded Plett's reports by neither responding to them nor changing their methods of immunisation, as the faculty at that time was still in favour of variolation. This article contains the available information and references concerning Plett's discovery, including the entire sources from 1802 and 1815 describing his findings. PMID:17338405

  1. Monitoring stream sediment loads in response to agriculture in Prince Edward Island, Canada.

    PubMed

    Alberto, Ashley; St-Hilaire, Andre; Courtenay, Simon C; van den Heuvel, Michael R

    2016-07-01

    Increased agricultural land use leads to accelerated erosion and deposition of fine sediment in surface water. Monitoring of suspended sediment yields has proven challenging due to the spatial and temporal variability of sediment loading. Reliable sediment yield calculations depend on accurate monitoring of these highly episodic sediment loading events. This study aims to quantify precipitation-induced loading of suspended sediments on Prince Edward Island, Canada. Turbidity is considered to be a reasonably accurate proxy for suspended sediment data. In this study, turbidity was used to monitor suspended sediment concentration (SSC) and was measured for 2 years (December 2012-2014) in three subwatersheds with varying degrees of agricultural land use ranging from 10 to 69 %. Comparison of three turbidity meter calibration methods, two using suspended streambed sediment and one using automated sampling during rainfall events, revealed that the use of SSC samples constructed from streambed sediment was not an accurate replacement for water column sampling during rainfall events for calibration. Different particle size distributions in the three rivers produced significant impacts on the calibration methods demonstrating the need for river-specific calibration. Rainfall-induced sediment loading was significantly greater in the most agriculturally impacted site only when the load per rainfall event was corrected for runoff volume (total flow minus baseflow), flow increase intensity (the slope between the start of a runoff event and the peak of the hydrograph), and season. Monitoring turbidity, in combination with sediment modeling, may offer the best option for management purposes.

  2. Demographics, management, and welfare of nonracing horses in Prince Edward Island.

    PubMed

    Christie, Julie L; Hewson, Caroline J; Riley, Christopher B; Mcniven, Mary A; Dohoo, Ian R; Bate, Luis A

    2004-12-01

    There are no detailed, representative, horse-level data about equine management practices in different parts of Canada. To help address this, the demographics, management, and welfare of 312 nonracing horses in Prince Edward Island were examined in a randomized, horse-level survey during summer 2002. Owners completed a pretested questionnaire, and a veterinarian examined each horse. Owners were experienced caregivers and the horses were generally in good condition. Areas for improvement included parasite control, dental and hoof care, and tail docking. The mean fecal egg count was 428 eggs per gram; 76% of owners never removed manure from the pasture. Sixty-two percent of horses had never had a veterinary dental examination. Many horses had hoof defects (excessively long hooves, 26.8%; hoof wall breaks, 32.0%; and white line disease, 8.5%). Many (54.9%) draft horses had docked tails. These results suggest owners might benefit their horses by receiving education in aspects of equine care.

  3. Weather Research and Forecasting Model Wind Sensitivity Study at Edwards Air Force Base, CA

    NASA Technical Reports Server (NTRS)

    Watson, Leela R.; Bauman, William H., III

    2008-01-01

    NASA prefers to land the space shuttle at Kennedy Space Center (KSC). When weather conditions violate Flight Rules at KSC, NASA will usually divert the shuttle landing to Edwards Air Force Base (EAFB) in Southern California. But forecasting surface winds at EAFB is a challenge for the Spaceflight Meteorology Group (SMG) forecasters due to the complex terrain that surrounds EAFB, One particular phenomena identified by SMG is that makes it difficult to forecast the EAFB surface winds is called "wind cycling". This occurs when wind speeds and directions oscillate among towers near the EAFB runway leading to a challenging deorbit bum forecast for shuttle landings. The large-scale numerical weather prediction models cannot properly resolve the wind field due to their coarse horizontal resolutions, so a properly tuned high-resolution mesoscale model is needed. The Weather Research and Forecasting (WRF) model meets this requirement. The AMU assessed the different WRF model options to determine which configuration best predicted surface wind speed and direction at EAFB, To do so, the AMU compared the WRF model performance using two hot start initializations with the Advanced Research WRF and Non-hydrostatic Mesoscale Model dynamical cores and compared model performance while varying the physics options.

  4. Effects of trichloroethylene and perchloroethylene on wild rodents at Edwards Air Force Base, California, USA

    USGS Publications Warehouse

    Spring, Sarah E.; Miles, A. Keith; Anderson, Michael J.

    2004-01-01

    Effects of inhalation of volatilized trichloroethylene (TCE) or perchloroethylene (PCE) were assessed based on the health and population size of wild, burrowing mammals at Edwards Air Force Base (CA, USA). Organic soil-vapor concentrations were measured at three sites with aquifer contamination of TCE or PCE of 5.5 to 77 mg/L and at two uncontaminated reference sites. Population estimates of kangaroo rats (Dipodomys merriami and D. panamintinus) as well as hematology, blood chemistry, and histopathology of kangaroo rats and deer mice (Peromyscus maniculatus) were compared between contaminated and uncontaminated populations. Maximum soil-gas concentrations associated with groundwater contamination were less than 1.5 μl/L of TCE and 0.07 μl/L of PCE. Population estimates of kangaroo rats were similar at contaminated and reference sites. Hematology, blood chemistry, and histopathology of kangaroo rats and deer mice indicated no evidence of health effects caused by exposure. Trichloroethylene or PCE in groundwater and in related soil gas did not appear to reduce the size of small mammal populations or impair the health of individuals.

  5. Roughness Scaling for the Edwards-Wilkinson Model on Small-World Substrates

    NASA Astrophysics Data System (ADS)

    Kozma, B.; Hastings, M. B.; Korniss, G.

    2004-03-01

    We studied the generalization of the Edwards-Wilkinson model to substrates with small-world topology(B. Kozma, M.B. Hastings, and G. Korniss, cond-mat/0309196 (2003).). We considered two implementations of this topology, the ``hard'' version of the network, where each site has exactly one random link of strength p, and the ``soft'' one, where each site on average has p random links of unit strength. Both versions are embedded in one dimension. The research is motivated in part by a recent general criterion for mean-field behavior(M.B. Hastings, Physical Review Letters 91), 098701 (2003). predicting the model to exhibit anomalous scaling on the soft network, and also by synchronization problems in scalable parallel computing(G. Korniss et al., Science 299), 677 (2003). We used impurity averaged perturbation technique to calculate the width in both the weak- and sparse-coupling limits, for the hard and soft network, respectively. The width remains finite in both cases in the infinite system-size limit, but scales differently as p tends to zero. We verified our analytic results by comparing them to those of exact numerical diagonalization.

  6. A newly identified apothecary in Boswell's Life of Johnson: Edward Ferrand (1691-1769).

    PubMed

    Caudle, James J; Bundock, Michael

    2014-05-01

    Ever since the publication of James Boswell's Life of Samuel Johnson (1791), it has been known that Johnson's young servant, the former slave Francis Barber 'ran away' at one point and worked for a London apothecary. But the apothecary was not named by Boswell and has not been identified by any of Johnson's numerous biographers nor in recent studies of Francis Barber. Research in surviving Boswell manuscripts, 18th-century London guides and the archives of the Society of Apothecaries prove the apothecary to have been Edward Ferrand. This article sets out the circumstances in which the reference to the anonymous apothecary came to appear in the Life of Johnson and reconstructs Ferrand's life and career. Examining Ferrand's origins, his social circumstances and his career, a case study is presented of a successful practitioner of the profession of apothecary in early Georgian Britain and a suggestion made as to why the distinguished apothecary came to provide a place of refuge for a teenaged runaway servant who had been a slave until he was about nine years old. PMID:24585592

  7. Weather Research and Forecasting Model Wind Sensitivity Study at Edwards Air Force Base, CA

    NASA Technical Reports Server (NTRS)

    Watson, Leela R.; Bauman, William H., III; Hoeth, Brian

    2009-01-01

    This abstract describes work that will be done by the Applied Meteorology Unit (AMU) in assessing the success of different model configurations in predicting "wind cycling" cases at Edwards Air Force Base, CA (EAFB), in which the wind speeds and directions oscillate among towers near the EAFB runway. The Weather Research and Forecasting (WRF) model allows users to choose among two dynamical cores - the Advanced Research WRF (ARW) and the Non-hydrostatic Mesoscale Model (NMM). There are also data assimilation analysis packages available for the initialization of the WRF model - the Local Analysis and Prediction System (LAPS) and the Advanced Regional Prediction System (ARPS) Data Analysis System (ADAS). Having a series of initialization options and WRF cores, as well as many options within each core, creates challenges for local forecasters, such as determining which configuration options are best to address specific forecast concerns. The goal of this project is to assess the different configurations available and determine which configuration will best predict surface wind speed and direction at EAFB.

  8. Dolomite dissolution rates and possible Holocene dedolomitization of water-bearing units in the Edwards aquifer, south-central Texas

    USGS Publications Warehouse

    Deike, R.G.

    1990-01-01

    Rates of dolomite dissolution can be used to test the concept, based on geomorphologic evidence, that a major part of the Edwards aquifer could have formed within the Holocene, a timeframe of approximately 10,000 years. During formation of the aquifer in the Edwards limestone (Cretaceous, Albian) of the Balcones fault zone, dolomite dissolution and porosity development were synchronous and the result of mixing-zone dedolomitization. Initiation of the mixing zone in the early Holocene (???11,000 years before present) is suggested by the maximum age of formation of major discharge sites that allowed the influx of meteoric water into brine-filled, dolomitic preaquifer units. Dedolomitization, the dissolution of dolomite and net precipitation of calcite, has left aquifer units that are calcitic, and 40 vol.% interconnected pore space. The mass of dolomite missing is obtained by comparison of stratigraphically equivalent altered and unaltered units. One dissolution rate (1.76 ?? 10-4 mmol dolomite kgH2O-1yr-1) is determined from this mass, 104yr reaction time, and a log-linear function describing the increase in mass discharge (three orders of magnitude) during aquifer formation. The second estimated dissolution rate is obtained from the mass transfer of dolomite to solution calculated from the increase in magnesium in pore fluids selected from the modern aquifer to represent a typical flowpath during aquifer formation. A reaction time of 104yr for this mass transfer yields a rate of 0.56 ?? 10-4 mmol dolomite kgH2O-1yr-1. Both of these rates are comparable to modern rates of dolomite dissolution (0.3 to 4.5 ?? 10-4 mmol dolomite kgH2O-1yr-1) calculated from measured reaction times in the Tertiary Floridan aquifer system in Florida and the Madison aquifer in the Mississippian Madison Limestone of the Northern Great Plains. Similarity of these rates to the estimated paleo-rates of dolomite dissolution supports a 104 yr reaction timeframe. The Holocene reaction time also

  9. Incidence of prenatal alcohol exposure in Prince Edward Island: a population-based descriptive study

    PubMed Central

    Bryanton, Janet; Boswall, Diane; McCarthy, Mary Jean; Fraser, Bonnie; Walsh, Donna; Freeman, Bridget; Koren, Gideon; Bigsby, Kathy

    2014-01-01

    Background Fetal alcohol spectrum disorder (FASD) is a leading preventable cause of neurodevelopmental disability in North America. The stigma associated with alcohol use and abuse during pregnancy makes it difficult to obtain information on prenatal alcohol use through self-reporting. We assessed the incidence of prenatal alcohol exposure in Prince Edward Island to facilitate future public health initiatives addressing FASD. Methods Prenatal alcohol exposure was examined via population-based collection of meconium and analysis of fatty acid ethyl esters (FAEEs). Fatty acid ethyl esters are nonoxidative metabolites of ethanol that are produced in the fetus. Meconium FAEE concentrations of 2.0 nmol/g or greater are indicative of frequent prenatal alcohol exposure during the last 2 trimesters of pregnancy. Samples were collected from 1307 neonates between Nov. 8, 2010, and Nov. 8, 2011, in hospitals in PEI, or from those born to mothers who resided in PEI but gave birth in Halifax, Nova Scotia. Samples were frozen and shipped for analysis. Fatty acid ethyl esters were analyzed by gas chromatography–mass spectrometry and quantified by means of deuterated internal standards. Results Of the 1307 samples collected, 1271 samples were successfully analyzed. Positive results for FAEEs were obtained in 3.1% (n = 39) of samples collected within the first 24 hours after birth. Interpretation Not all neonates exposed to heavy prenatal alcohol in utero will exhibit FASD; based on current estimates of predictive value for disease by exposure, our findings suggest that 1.3% of neonates born in PEI during this 1-year period will have FASD. In its application to an entire provincial birth cohort, this study successfully implemented a public health–centred approach for evaluating population-based risk of FASD, with implications for practice across Canada. PMID:25077128

  10. A prepared mind--Ernest Edward Tyzzer's legacy of research into avian diseases.

    PubMed

    Williams, R B

    2013-12-01

    Ernest Edward Tyzzer (1875-1965) was a physician, specializing at first (1902-1916) in cancer research and then from 1916 as a parasitologist. He was born of English parents in Wakefield, Massachusetts, where he lived all his life. Educated in Wakefield public schools, Brown University (Ph.B., A.M., Hon. Sc.D.), and Harvard University (M.D.), he established during his 40-yr career (1902-1942) an international reputation in oncology, pathology, virology, bacteriology, parasitology, and taxonomic zoology in relation to human and veterinary medicine. His contributions to knowledge of avian diseases were outstanding and wide-ranging. Seminal work included: new descriptions of tumors in chickens; the first record of Cryptosporidium in birds; studies on the biology, morphology, in vitro culture, and epizootiology of the blackhead (histomonosis) parasite and its reclassification under a new genus Histomonas; descriptions of eight new taxa of amebae and flagellates in chickens, turkeys, and ruffed grouse; descriptions of seven new species of Eimeria in chickens, turkeys, pheasants, and quail as well as studies on their biology, immunogenicity, virulence, and epizootiology; a description of the trematode Collyriclum in English sparrows; the first record of mycosis in ruffed grouse; the recognition of birds as a source of equine encephalomyelitis infections of humans; the first American record of infectious sinusitis in turkeys and discovery of a curative treatment; and studies of Newcastle disease and avian influenza during the war research program of the 1940s. Application of Tyzzer's histomonosis research to farm practice saved the Massachusetts turkey industry from extinction in the 1920s and significantly influenced the recovery of turkey farming nationally.

  11. A Fractal Interpretation of Controlled-Source Helicopter Electromagnetic Survey Data: Seco Creek, Edwards Aquifer, TX

    NASA Astrophysics Data System (ADS)

    Decker, K. T.; Everett, M. E.

    2009-12-01

    The Edwards aquifer lies in the structurally complex Balcones fault zone and supplies water to the growing city of San Antonio. To ensure that future demands for water are met, the hydrological and geophysical properties of the aquifer must be well-understood. In most settings, fracture lengths and displacements occur in power-law distributions. Fracture distribution plays an important role in determining electrical and hydraulic current flowpaths. 1-D synthetic models of the controlled-source electromagnetic (CSEM) response for layered models with a fractured layer at depth described by the roughness parameter βV, such that 0≤βV<1, associated with the power-law length-scale dependence of electrical conductivity are developed. A value of βV = 0 represents homogeneous, continuous media, while a value of 0<βV<1 shows that roughness exists. The Seco Creek frequency-domain helicopter electromagnetic survey data set is analyzed by introducing the similarly defined roughness parameter βH to detect lateral roughness along survey lines. Fourier transforming the apparent resistivity as a function of position along flight line into wavenumber domain using a 256-point sliding window gives the power spectral density (PSD) plot for each line. The value of βH is the slope of the least squares regression for the PSD in each 256-point window. Changes in βH with distance along the flight line are plotted. Large values of βH are found near well-known large fractures and maps of βH produced by interpolating values of βH along survey lines suggest previously undetected structure at depth.

  12. Effects of contaminants on reproductive success of aquatic birds nesting at Edwards Air Force Base, California

    USGS Publications Warehouse

    Hothem, R.L.; Crayon, J.J.; Law, M.A.

    2006-01-01

    Contamination by organochlorine pesticides (OCs), polychlorinated biphenyls, metals, and trace elements at Edwards Air Force Base (EAFB), located in the Mojave Desert, could adversely affect nesting aquatic birds, especially at the sewage lagoons that comprise Piute Ponds. Estimates of avian reproduction, in conjunction with analyses of eggs and avian foods for contaminant residues, may indicate the potential for negative effects on avian populations. From 1996 to 1999, we conducted studies at the Piute Ponds area of EAFB to evaluate the impacts of contaminants on nesting birds. Avian reproduction was evaluated in 1999. Eggs were collected for chemical analyses in 1996 and 1999, and African clawed frogs (Xenopus laevis), a likely food source, were collected for chemical analyses in 1998. Avian species occupying the higher trophic levels-black-crowned night-heron (Nycticorax nycticorax), white-faced ibis (Plegadis chihi), and American avocet (Recurvirostra americana)-generally bioaccumulated higher concentrations of contaminants in their eggs. Reproductive success and egg hatchability of night-herons and white-faced ibises in the Piute Ponds were similar to results observed at other western colonies. Deformities were observed in only one embryo in this study, but concentrations of contaminants evaluated in this ibis embryo were considered insufficient to have caused the deformities. Because clawed frogs, a primary prey item for night-herons at Piute Ponds, had no detectable levels of any OCs, it is likely that OCs found in night-heron eggs were acquired from the wintering grounds rather than from EAFB. The presence of isomers of dichlorodiphenyltrichloroethane (DDT) in ibis eggs indicated recent exposure, but invertebrates used for food by ibises were not sampled at Piute Ponds, and conclusions about the source of OCs in ibis eggs could not be made. Concentrations of contaminants in random and failed eggs of individual species were not different, and we concluded

  13. Groundwater nitrate concentration evolution under climate change and agricultural adaptation scenarios: Prince Edward Island, Canada

    NASA Astrophysics Data System (ADS)

    Paradis, Daniel; Vigneault, Harold; Lefebvre, René; Savard, Martine M.; Ballard, Jean-Marc; Qian, Budong

    2016-03-01

    Nitrate (N-NO3) concentration in groundwater, the sole source of potable water in Prince Edward Island (PEI, Canada), currently exceeds the 10 mg L-1 (N-NO3) health threshold for drinking water in 6 % of domestic wells. Increasing climatic and socio-economic pressures on PEI agriculture may further deteriorate groundwater quality. This study assesses how groundwater nitrate concentration could evolve due to the forecasted climate change and its related potential changes in agricultural practices. For this purpose, a tridimensional numerical groundwater flow and mass transport model was developed for the aquifer system of the entire Island (5660 km2). A number of different groundwater flow and mass transport simulations were made to evaluate the potential impact of the projected climate change and agricultural adaptation. According to the simulations for year 2050, N-NO3 concentration would increase due to two main causes: (1) the progressive attainment of steady-state conditions related to present-day nitrogen loadings, and (2) the increase in nitrogen loadings due to changes in agricultural practices provoked by future climatic conditions. The combined effects of equilibration with loadings, climate and agricultural adaptation would lead to a 25 to 32 % increase in N-NO3 concentration over the Island aquifer system. The change in groundwater recharge regime induced by climate change (with current agricultural practices) would only contribute 0 to 6 % of that increase for the various climate scenarios. Moreover, simulated trends in groundwater N-NO3 concentration suggest that an increased number of domestic wells (more than doubling) would exceed the nitrate drinking water criteria. This study underlines the need to develop and apply better agricultural management practices to ensure sustainability of long-term groundwater resources. The simulations also show that observable benefits from positive changes in agricultural practices would be delayed in time due to

  14. Effects of contaminants on reproductive success of aquatic birds nesting at Edwards Air Force Base, California.

    PubMed

    Hothem, R L; Crayon, J J; Law, M A

    2006-11-01

    Contamination by organochlorine pesticides (OCs), polychlorinated biphenyls, metals, and trace elements at Edwards Air Force Base (EAFB), located in the Mojave Desert, could adversely affect nesting aquatic birds, especially at the sewage lagoons that comprise Piute Ponds. Estimates of avian reproduction, in conjunction with analyses of eggs and avian foods for contaminant residues, may indicate the potential for negative effects on avian populations. From 1996 to 1999, we conducted studies at the Piute Ponds area of EAFB to evaluate the impacts of contaminants on nesting birds. Avian reproduction was evaluated in 1999. Eggs were collected for chemical analyses in 1996 and 1999, and African clawed frogs (Xenopus laevis), a likely food source, were collected for chemical analyses in 1998. Avian species occupying the higher trophic levels--black-crowned night-heron (Nycticorax nycticorax), white-faced ibis (Plegadis chihi), and American avocet (Recurvirostra americana)--generally bioaccumulated higher concentrations of contaminants in their eggs. Reproductive success and egg hatchability of night-herons and white-faced ibises in the Piute Ponds were similar to results observed at other western colonies. Deformities were observed in only one embryo in this study, but concentrations of contaminants evaluated in this ibis embryo were considered insufficient to have caused the deformities. Because clawed frogs, a primary prey item for night-herons at Piute Ponds, had no detectable levels of any OCs, it is likely that OCs found in night-heron eggs were acquired from the wintering grounds rather than from EAFB. The presence of isomers of dichlorodiphenyltrichloroethane (DDT) in ibis eggs indicated recent exposure, but invertebrates used for food by ibises were not sampled at Piute Ponds, and conclusions about the source of OCs in ibis eggs could not be made. Concentrations of contaminants in random and failed eggs of individual species were not different, and we concluded

  15. Prevalence of Batrachochytrium dendrobatidis in three species of wild frogs on Prince Edward Island, Canada.

    PubMed

    Forzán, M J; Vanderstichel, R; Hogan, N S; Teather, K; Wood, J

    2010-09-01

    Chytridiomycosis, caused by the fungus Batrachochytrium dendrobatidis (Bd), has resulted in the decline or extinction of approximately 200 frog species worldwide. It has been reported throughout much of North America, but its presence on Prince Edward Island (PEI), on the eastern coast of Canada, was unknown. To determine the presence and prevalence of Bd on PEI, skin swabs were collected from 115 frogs from 18 separate sites across the province during the summer of 2009. The swabs were tested through single round end-point PCR for the presence of Bd DNA. Thirty-one frogs were positive, including 25/93 (27%) green frogs Lithobates (Rana) clamitans, 5/20 (25%) northern leopard frogs L. (R.) pipiens, and 1/2 (50%) wood frogs L. sylvaticus (formerly R. sylvatica); 12 of the 18 (67%) sites had at least 1 positive frog. The overall prevalence of Bd infection was estimated at 26.9% (7.2-46.7%, 95% CI). Prevalence amongst green frogs and leopard frogs was similar, but green frogs had a stronger PCR signal when compared to leopard frogs, regardless of age (p < 0.001) and body length (p = 0.476). Amongst green frogs, juveniles were more frequently positive than adults (p = 0.001). Green frogs may be the most reliable species to sample when looking for Bd in eastern North America. The 1 wood frog positive for Bd was found dead from chytridiomycosis; none of the other frogs that were positive for Bd by PCR showed any obvious signs of illness. Further monitoring will be required to determine what effect Bd infection has on amphibian population health on PEI.

  16. Effects of contaminants on reproductive success of aquatic birds nesting at Edwards Air Force Base, California.

    PubMed

    Hothem, R L; Crayon, J J; Law, M A

    2006-11-01

    Contamination by organochlorine pesticides (OCs), polychlorinated biphenyls, metals, and trace elements at Edwards Air Force Base (EAFB), located in the Mojave Desert, could adversely affect nesting aquatic birds, especially at the sewage lagoons that comprise Piute Ponds. Estimates of avian reproduction, in conjunction with analyses of eggs and avian foods for contaminant residues, may indicate the potential for negative effects on avian populations. From 1996 to 1999, we conducted studies at the Piute Ponds area of EAFB to evaluate the impacts of contaminants on nesting birds. Avian reproduction was evaluated in 1999. Eggs were collected for chemical analyses in 1996 and 1999, and African clawed frogs (Xenopus laevis), a likely food source, were collected for chemical analyses in 1998. Avian species occupying the higher trophic levels--black-crowned night-heron (Nycticorax nycticorax), white-faced ibis (Plegadis chihi), and American avocet (Recurvirostra americana)--generally bioaccumulated higher concentrations of contaminants in their eggs. Reproductive success and egg hatchability of night-herons and white-faced ibises in the Piute Ponds were similar to results observed at other western colonies. Deformities were observed in only one embryo in this study, but concentrations of contaminants evaluated in this ibis embryo were considered insufficient to have caused the deformities. Because clawed frogs, a primary prey item for night-herons at Piute Ponds, had no detectable levels of any OCs, it is likely that OCs found in night-heron eggs were acquired from the wintering grounds rather than from EAFB. The presence of isomers of dichlorodiphenyltrichloroethane (DDT) in ibis eggs indicated recent exposure, but invertebrates used for food by ibises were not sampled at Piute Ponds, and conclusions about the source of OCs in ibis eggs could not be made. Concentrations of contaminants in random and failed eggs of individual species were not different, and we concluded

  17. Groundwater nitrate concentration evolution under climate change and agricultural adaptation scenarios: Prince Edward Island, Canada

    NASA Astrophysics Data System (ADS)

    Paradis, D.; Vigneault, H.; Lefebvre, R.; Savard, M. M.; Ballard, J.-M.; Qian, B.

    2015-08-01

    Nitrate (N-NO3) concentration in groundwater, the sole source of potable water in Prince Edward Island (PEI, Canada), currently exceeds the 10 mg L-1 (N-NO3) health threshold for drinking water in 6 % of domestic wells. Increasing climatic and socio-economic pressures on PEI agriculture may further deteriorate groundwater quality. This study assesses how groundwater nitrate concentrations could evolve due to the forecasted climate change and its related potential changes in agricultural practices. For this purpose, a tridimensional numerical groundwater flow and mass transport model was developed for the aquifer system of the entire Island (5660 km2). A number of different groundwater flow and mass transport simulations were made to evaluate the potential impact of the projected climate change and agricultural adaptation. According to the simulations for year 2050, N-NO3 concentration would increase due to two main causes: (1) the progressive attainment of steady-state conditions related to present-day nitrogen loadings, and (2) the increase in nitrogen loadings due to changes in agricultural practices provoked by future climatic conditions. The combined effects of equilibration with loadings, climate and agricultural adaptation would lead to a 25 to 32 % increase in N-NO3 concentration over the Island aquifer system. Climate change alone (practices maintained at their current level) would contribute only 0 to 6 % to that increase according to the various climate scenarios. Moreover, simulated trends in groundwater N-NO3 concentration suggest that an increased number of domestic wells (more than doubling) would exceed the nitrate drinking water criteria. This study underlines the need to develop and apply better agricultural management practices to ensure sustainability of long-term groundwater resources. The simulations also show that observable benefits from positive changes in agricultural practices would be delayed in time due to the slow dynamics of nitrate

  18. STS-76 Landing - Space Shuttle Atlantis Lands at Edwards Air Force Base, Drag Chute Deploy

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The space shuttle Atlantis touches down on the runway at Edwards, California, at approximately 5:29 a.m. Pacific Standard Time after completing the highly successful STS-76 mission to deliver Astronaut Shannon Lucid to the Russian Space Station Mir. She was the first American woman to serve as a Mir station researcher. Atlantis was originally scheduled to land at Kennedy Space Center, Florida, but bad weather there both 30 and 31 March necessitated a landing at the backup site at Edwards. This photo shows the drag chute deployed to help the shuttle roll to a stop. Mission commander for STS-76 was Kevin P. Chilton, and Richard A. Searfoss was the pilot. Ronald M. Sega was payload commander and mission specialist-1. Mission specialists were Richard Clifford, Linda Godwin and Shannon Lucid. The mission also featured a spacewalk while Atlantis was docked to Mir and experiments aboard the SPACEHAB module. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be

  19. STS-76 Landing - Space Shuttle Atlantis Lands at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The space shuttle Atlantis touches down on the runway at Edwards, California, at approximately 5:29 a.m. Pacific Standard Time on 31 March 1996 after completing the highly successful STS-76 mission to deliver Astronaut Shannon Lucid to the Russian Space Station Mir. She was the first American woman to serve as a Mir station researcher. Atlantis was originally scheduled to land at Kennedy Space Center, Florida, but bad weather there both March 30 and March 31 necessitated a landing at the backup site at Edwards AFB. Mission commander for STS-76 was Kevin P. Chilton. Richard A. Searfoss was the pilot. Serving as payload commander and mission specialist-1 was Ronald M. Sega. Mission specialist-2 was Richard Clifford. Linda Godwin served as mission specialist-3, and Shannon Lucid was mission specialist-4. The mission also featured a spacewalk while Atlantis was docked to Mir and experiments aboard the SPACEHAB module. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they

  20. STS-76 Landing - Space Shuttle Atlantis Lands at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The space shuttle Atlantis prepares to touch down on the runway at Edwards, California, at approximately 5:29 a.m. Pacific Standard Time after completing the highly successful STS-76 mission to deliver Astronaut Shannon Lucid to the Russian Space Station Mir. Lucid was the first American woman to serve as a Mir station researcher. Atlantis was originally scheduled to land at Kennedy Space Center, Florida, but bad weather there both 30 March and 31 March necessitated a landing at the backup site at Edwards on the latter date. Mission commander for STS-76 was Kevin P. Chilton, and Richard A. Searfoss was the pilot. Ronald M. Sega was the payload commander and mission specialist-1. Other mission specialists were Richard Clifford, Linda Godwin, and Shannon Lucid. The mission also featured a spacewalk while Atlantis was docked to Mir and experiments aboard the SPACEHAB module. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are

  1. A Biography of Distinguished Scientist Gilbert Newton Lewis (by Edward S. Lewis)

    NASA Astrophysics Data System (ADS)

    Harris, Reviewed By Harold H.

    1999-11-01

    The Edward Mellen Press: Lewiston, NY, 1998. 114 pp + index. ISBN 0-7734-8284-9. $69.95. There may not be a surname better known to students of chemistry than Lewis, from the Lewis electron-dot diagrams and the Lewis theory of acids and bases. More advanced students may know of the groundbreaking textbook Thermodynamics, by Lewis and Randall. Yet few Americans know much about this remarkable U.S.-born scholar, whose contributions equal those of the greatest scientists. He is a chemist-educator of whom we should be as proud and as well informed as we are of Linus Pauling, who was part of the westward movement of science in this country that G. N. Lewis began, or of the recently deceased Glenn Seaborg, who was one of the many students of Lewis who achieved renown. Gilbert N. Lewis was born in Weymouth, Massachusetts, in 1875, but his family moved to near Lincoln, Nebraska, in 1884. He spent two years at the University of Nebraska, but then moved to Harvard when his father became an executive at Merchants Trust Company in Boston. Young Lewis (then only 17) was also said to have been disappointed with the quality of education in Nebraska, and this may have been part of the impetus for the family's move east. After earning his baccalaureate at Harvard, he taught for a year at Phillips Andover Academy before returning to Harvard to study for his doctorate, which he completed 100 years ago, in 1899, under T. W. Richards. Lewis's doctoral work was on the thermodynamics of zinc and cadmium amalgams. At that time, physical chemistry was only beginning to achieve recognition as a branch of science, and its boundaries were ill defined. Edward Lewis quotes his father as often saying, "Physical chemistry is anything interesting." Like many chemists of his time, Lewis went to Europe to complete his preparation for a career; he was in the laboratories of Ostwald in Leipzig and Nernst in Göttingen in 1900-1901. On his return to the United States, he was an instructor at Harvard

  2. Feasibility and safety of early discharge after transfemoral transcatheter aortic valve implantation with the Edwards SAPIEN-XT prosthesis.

    PubMed

    Durand, Eric; Eltchaninoff, Hélène; Canville, Alexandre; Bouhzam, Najime; Godin, Matthieu; Tron, Christophe; Rodriguez, Carlos; Litzler, Pierre-Yves; Bauer, Fabrice; Cribier, Alain

    2015-04-15

    There is currently no consensus on the duration of hospitalization required after transfemoral transcatheter aortic valve implantation (TAVI). We report the feasibility and safety of early discharge after TAVI with the Edwards SAPIEN-XT prosthesis. From 2009 to 2013, 337 patients underwent transfemoral TAVI with the Edwards SAPIEN-XT prosthesis using local anesthesia and were discharged home either early (≤3 days, Early Discharge group, n = 121) or after 3 days (Late Discharge group, n = 216). The primary end point of the study combined death and rehospitalization from discharge to 30-day follow-up. Patients in the Early Discharge group were less symptomatic (New York Heart Association class ≥III: 64.5% vs 75.5%, p = 0.01) and had less renal failure (creatinine: 102.1 ± 41.0 vs 113.3 ± 58.9 μmol/L, p = 0.04), atrial fibrillation (33.1% vs 46.3%, p = 0.02), and previous balloon aortic valvuloplasty (11.6% vs 23.1%, p = 0.01) and were more likely to have a pacemaker before TAVI (16.5% vs 8.3%, p = 0.02). Pre-existing pacemaker (p = 0.05) and the absence of acute kidney injury (p = 0.02) were independent predictors of an early discharge, whereas previous balloon aortic valvuloplasty (p = 0.03) and post-TAVI blood transfusions (p = 0.002) were independent predictors of late discharge. The primary end point occurred in 4 patients (3.3%) in the Early Discharge group and in 11 patients (5.1%) in the Late Discharge group (p = 0.58). In conclusion, the results of our study suggest that early discharge after transfemoral TAVI using the Edwards SAPIEN-XT prosthesis is feasible and safe in selected patients. PMID:25726383

  3. Upper Albian rudist buildups of the Edwards Formation in central Texas: A GPR-assisted reservoir analog study

    NASA Astrophysics Data System (ADS)

    Mukherjee, Damayanti; Khan, Shuhab D.; Sullivan, Charlotte

    2012-03-01

    Albian rudist-associated shallow water carbonates form important hydrocarbon reservoirs in the Middle East, Mexico, and the United States. Outcrops of rudist-bearing shallow water carbonates are common across parts of central Texas, USA, and in places display lateral and vertical relationships that form important analogs for the subsurface distribution and heterogeneity of hydrocarbon reservoirs and seals. In particular, the walls and spillways of several lakes in central Texas provide ideal conditions for the investigation by ground-penetrating radar (GPR) of the three-dimensional geometries of platform interior rudist lithofacies belts. This study integrates outcrop studies and GPR surveys to clarify lateral and vertical facies relations of rudist-bearing lithofacies in the Cretaceous Edwards Formation (Fredericksburg Group) that are partially exposed in spillways and gullies near Lake Georgetown and Belton Lake in central Texas, USA. GPR data illuminated four types of mounds that have distinct three-dimensional geometries, lithofacies, and biota and that record both seaward to leeward changes and vertical changes from below wavebase to within wavebase. The lowermost mounds are high relief circular caprinid mounds that mark the aggradational part of the Edwards lithostratigraphic unit at our study locality. Well cemented, low relief toucasid-foraminiferal mounds and grainstones cap these caprinid-dominated buildups. Weakly cemented, circular, flat-topped radiolitid-caprinid-toucasid mounds developed above the toucasid mounds and low relief, often sucrosic-dolomitized mounds constitute the most shallow water rudist accumulations. Stromatolitic dolomites record final filling of accommodation space on the Edwards platform. GPR provides an unparalleled view of the three-dimensional growth, vertical accretion, and progradation of these mounds and lithofacies through time, and the geoelectrical signatures provide insight on porosity and permeability of the lithofacies

  4. Further contributions to the Hydradephaga (Coleoptera, Haliplidae, Gyrinidae and Dytiscidae) fauna of Prince Edward Island, Canada: new records, distributions and faunal composition.

    PubMed

    Alarie, Yves

    2016-01-01

    The Haliplidae, Gyrinidae and Dytiscidae (Coleoptera) of Prince Edward Island, Canada were surveyed during the years 2004-2005. A total of 2450 individuals from 79 species were collected from 98 different localities, among which 30 species are newly recorded from that region. Among these, Acilius sylvanus Hilsenhoff, Rhantus consimilis Motschulsky and Neoporus sulcipennis (Fall) stand out as representing the easternmost reports of these species in Canada. Once removed, Gyrinus aquiris LeConte (Gyrinidae) is reinstated in the faunal list of Prince Edward Island. According to this study and literature 84 species of Hydradephaga are currently known from Prince Edward Island. The Nearctic component of the fauna is made up of 68 species (80.9%) and the Holarctic component of 16 species (19.1%). Most species are characteristic of the Boreal and Atlantic Maritime Ecozones and have a transcontinental distribution. In an examination of the Hydradephaga of insular portions of Atlantic Canada, we found that despite significantly different land areas and different distances to the neighbouring continental mainland the island faunas of Prince Edward Island and insular Newfoundland are very similar in the number of species (84 and 94 species respectively) despite differences in composition. With a land area significantly larger than that of Prince Edward Island, however, the fauna of Cape Breton Island was 39% smaller consisting of 53 species. This difference could be due to the comparative lack of collecting efforts on Cape Breton Island. PMID:27408603

  5. Identification and Mapping of the Edwards Stratigraphic Sequence in the State of Chihuahua Assisted by ten ArcMap Based Layers

    NASA Astrophysics Data System (ADS)

    Martinez-Pina, C.; Granados, A.; Goodell, P.

    2007-05-01

    Edwards Formation is a reef limestone that hosts one of the largest aquifers of the State of Texas. In 2004 the United States and Mexico signed an agreement intended to characterize and identify the shared binational underground resources. Texas Water Development Board Report 360 established for the Edwards Aquifer an area of more than 31,000 km2, half of which is in the State of Coahuila, Mexico (the agreement did not include the State of Chihuahua). This led to the idea that Chihuahua may also have hydrologic potential in the Edwards equivalent, where numerous large cavern systems are already recognized (Naica's Sword Cavern, and the Coyame, Nombre de Dios and Bocagrande Caverns). The objective of this study is to establish the existence, in the State of Chihuahua, of the stratigraphic sequence and geohydrologic properties such as faulting, sinkholes, and springs, within the Edwards equivalent. The Consejo de Recursos Minerales geologic map, INEGI's hydrologic study, petroleum, mining and hydrogeology studies of Chihuahua, and many others, constitute the database used. ArcMap is used to define the geologic framework and construct different thematic layers (structural, lithological, hydrological) that would aid in the identification of the stratigraphic sequence. The results show that all the Edwards Stratigraphic Sequence (ESS) exists in Chihuahua; that there are isolated areas of groundwater production in eastern Chihuahua possibly from ESS but this is not well established. Overall the ESS presents an unusual opportunity as a potentially productive aquifer in the State of Chihuahua.

  6. Further contributions to the Hydradephaga (Coleoptera, Haliplidae, Gyrinidae and Dytiscidae) fauna of Prince Edward Island, Canada: new records, distributions and faunal composition

    PubMed Central

    Alarie, Yves

    2016-01-01

    Abstract The Haliplidae, Gyrinidae and Dytiscidae (Coleoptera) of Prince Edward Island, Canada were surveyed during the years 2004–2005. A total of 2450 individuals from 79 species were collected from 98 different localities, among which 30 species are newly recorded from that region. Among these, Acilius sylvanus Hilsenhoff, Rhantus consimilis Motschulsky and Neoporus sulcipennis (Fall) stand out as representing the easternmost reports of these species in Canada. Once removed, Gyrinus aquiris LeConte (Gyrinidae) is reinstated in the faunal list of Prince Edward Island. According to this study and literature 84 species of Hydradephaga are currently known from Prince Edward Island. The Nearctic component of the fauna is made up of 68 species (80.9%) and the Holarctic component of 16 species (19.1%). Most species are characteristic of the Boreal and Atlantic Maritime Ecozones and have a transcontinental distribution. In an examination of the Hydradephaga of insular portions of Atlantic Canada, we found that despite significantly different land areas and different distances to the neighbouring continental mainland the island faunas of Prince Edward Island and insular Newfoundland are very similar in the number of species (84 and 94 species respectively) despite differences in composition. With a land area significantly larger than that of Prince Edward Island, however, the fauna of Cape Breton Island was 39% smaller consisting of 53 species. This difference could be due to the comparative lack of collecting efforts on Cape Breton Island. PMID:27408603

  7. Nematocarcinus Milne Edwards, 1881 (Crustacea, Decapoda) from Southwestern Atlantic, including the Southern Mid-Atlantic Ridge area.

    PubMed

    Cardoso, Irene A; Burukovsky, Rudolf N

    2014-01-01

    The deep sea shrimp genus Nematocarcinus Milne Edwards, 1881 includes 47 species, ten of them have been recorded from the Atlantic Ocean. Herein, material sampled during three scientific projects (REVIZEE Central Fishery project; Campos Basin Deep Sea Environmental Project; Evaluation of Environmental Heterogeneity in the Campos Basin) made in the Southwestern Atlantic, off Brazil, is examined. In addition, material sampled from the South Mid Atlantic Ridge (MAR-ECO Project) was also examined. Four species are recorded for the first time to the southwestern Atlantic Ocean including Mid Atlantic Ridge area: Nematocarcinus faxoni Burukovsky, 2001; N. gracilipes Filhol, 1884; N. rotundus Crosnier & Forest, 1973 and N. tenuipes Spence-Bate, 1888. PMID:25543942

  8. Reflections on working for Senator Edward Kennedy, a vital ally in the effort to improve mental health access and care.

    PubMed

    Pollack, David A

    2010-04-01

    The author worked as a health policy fellow in the office of Senator Edward M. Kennedy in 1999. These reflections on that experience provide a description of the ambience of working on health policy issues in the US Congress, how the author utilized his community psychiatric knowledge and skills to assist in the process of developing and promoting various health and mental health related issues, and what it was like working in the Kennedy office. In the wake of his death, the Senator's long and influential career and especially his role in advancing health and mental health access and care improvement cannot be overstated.

  9. Nematocarcinus Milne Edwards, 1881 (Crustacea, Decapoda) from Southwestern Atlantic, including the Southern Mid-Atlantic Ridge area.

    PubMed

    Cardoso, Irene A; Burukovsky, Rudolf N

    2014-01-01

    The deep sea shrimp genus Nematocarcinus Milne Edwards, 1881 includes 47 species, ten of them have been recorded from the Atlantic Ocean. Herein, material sampled during three scientific projects (REVIZEE Central Fishery project; Campos Basin Deep Sea Environmental Project; Evaluation of Environmental Heterogeneity in the Campos Basin) made in the Southwestern Atlantic, off Brazil, is examined. In addition, material sampled from the South Mid Atlantic Ridge (MAR-ECO Project) was also examined. Four species are recorded for the first time to the southwestern Atlantic Ocean including Mid Atlantic Ridge area: Nematocarcinus faxoni Burukovsky, 2001; N. gracilipes Filhol, 1884; N. rotundus Crosnier & Forest, 1973 and N. tenuipes Spence-Bate, 1888.

  10. In celebration of the 200th anniversary of Edward Jenner's Inquiry into the causes and effects of the variolae vaccinae.

    PubMed

    Brunham, R C; Coombs, K M

    1998-09-01

    This review commemorates the 200th anniversary of Edward Jenner's development of a vaccine for variola, the cause of smallpox, and the 20th anniversary of its eradication. Jenner's original 23 case reports are briefly revisited within the context of earlier attempts to prevent this dreaded disease and in light of the current understanding of vaccinology and immunology. In addition, with molecular biological information available about many pox viruses and detailed sequence knowledge of some, it is now possible to appreciate Jenner's prescient accomplishments more fully.

  11. A multiphased approach to groundwater investigations for the Edwards-Trinity and related aquifers in the Pecos County region, Texas

    USGS Publications Warehouse

    Thomas, Jonathan V.

    2014-01-01

    The Edwards-Trinity aquifer is a vital groundwater resource for agricultural, industrial, and public supply uses in the Pecos County region of western Texas. Resource managers would like to understand the future availability of water in the Edwards-Trinity aquifer in the Pecos County region and the effects of the possible increase or temporal redistribution of groundwater withdrawals. To provide resource managers with that information, the U.S. Geological Survey (USGS), in cooperation with the Middle Pecos Groundwater Conservation District, Pecos County, City of Fort Stockton, Brewster County, and Pecos County Water Control and Improvement District No. 1, completed a three-phase study of the Edwards-Trinity and related aquifers in parts of Brewster, Jeff Davis, Pecos, and Reeves Counties. The first phase was to collect groundwater, surface-water, geochemical, geophysical, and geologic data in the study area and develop a geodatabase of historical and collected data. Data compiled in the first phase of the study were used to develop the conceptual model in the second phase of the study. The third phase of the study involved the development and calibration of a numerical groundwater-flow model of the Edwards-Trinity aquifer to simulate groundwater conditions based on various groundwater-withdrawal scenarios. Analysis of well, geophysical, geochemical, and hydrologic data contributed to the development of the conceptual model in phase 1. Lithologic information obtained from well reports and geophysical data was used to describe the hydrostratigraphy and structural features of the groundwater-flow system, and aquifer-test data were used to estimate aquifer hydraulic properties. Geochemical data were used to evaluate groundwater-flow paths, water-rock interaction, aquifer interaction, and the mixing of water from different sources in phase 2. Groundwater-level data also were used to evaluate aquifer interaction, as well as to develop a potentiometric-surface map

  12. Economic efficiency and cost implications of habitat conservation: An example in the context of the Edwards Aquifer region

    NASA Astrophysics Data System (ADS)

    Gillig, Dhazn; McCarl, Bruce A.; Jones, Lonnie L.; Boadu, Frederick

    2004-04-01

    Groundwater management in the Edwards Aquifer in Texas is in the process of moving away from a traditional right of capture economic regime toward a more environmentally sensitive scheme designed to preserve endangered species habitats. This study explores economic and environmental implications of proposed groundwater management and water development strategies under a proposed regional Habitat Conservation Plan. Results show that enhancing the habitat by augmenting water flow costs $109-1427 per acre-foot and that regional water development would be accelerated by the more extreme possibilities under the Habitat Conservation Plan. The findings also indicate that a water market would improve regional welfare and lower water development but worsen environmental attributes.

  13. Joint min-max distribution and Edwards-Anderson's order parameter of the circular 1/f-noise model

    NASA Astrophysics Data System (ADS)

    Cao, Xiangyu; Le Doussal, Pierre

    2016-05-01

    We calculate the joint min-max distribution and the Edwards-Anderson's order parameter for the circular model of 1/f-noise. Both quantities, as well as generalisations, are obtained exactly by combining the freezing-duality conjecture and Jack-polynomial techniques. Numerical checks come with significantly improved control of finite-size effects in the glassy phase, and the results convincingly validate the freezing-duality conjecture. Application to diffusive dynamics is discussed. We also provide a formula for the pre-factor ratio of the joint/marginal Carpentier-Le Doussal tail for minimum/maximum which applies to any logarithmic random energy model.

  14. Phonocardiographic method of assessing changes in left ventricular function after Starr-Edwards replacement of aortic valve

    PubMed Central

    Gibson, D. G.; Broder, G.; Sowton, E.

    1970-01-01

    A phonocardiographic method is described for measuring the time taken by the ball of a Starr-Edwards prosthesis to move to the apex of the cage at the onset of left ventricular ejection, and from this its acceleration can be derived. The acceleration is conspicuously increased in post-ectopic beats and in exercise, but is unaffected by posture and tachycardia induced by atropine or ventricular pacing. It is suggested that the acceleration of the ball is related to the initial acceleration of blood into the ascending aorta. Images PMID:5440511

  15. Hydrostratigraphic subdivisions and fault barriers of the Edwards aquifer, south-central Texas, U.S.A.

    USGS Publications Warehouse

    Maclay, R.W.; Small, T.A.

    1983-01-01

    The karstic Edwards Limestone within the Balcones Fault Zone of south-central Texas forms a productive confined aquifer that consists predominately of dense carbonate rocks and contains several layers of highly permeable and porous honeycombed rocks that have been produced by the leaching of evaporitic, tidal flat or reefal deposits. Fractures have hydraulically interconnected these layers at some places. Faults, however, commonly place rocks of very high-permeability opposite rocks of very low permeability, thus creating a lateral discontinuity and a flow barrier. At places, fault barriers probably cause partial to almost complete blockage of groundwater flow normal to the fault. ?? 1982.

  16. [Edward Wilhelm Drescher--the founder of pediatric surgery in West Pomerania].

    PubMed

    Pacanowski, J H

    1999-01-01

    Professor Edward Wilhelm Drescher--an eminent Polish pediatric surgeon and pioneer of this specialization in West Pomerania--was born in 1912 in Biłgoraj. His young years he spent in his parents familial town Kalisz, where he attended a very famous college--State Humanistic Grammar-School. In 1937 he graduated from Faculty of Medicine at the Warsaw University. Next year he started his career as a surgeon in the Surgery at Orthopedic Ward of Pediatric Clinic in Warsaw, which was directed by prof. Jan Kossakowski--excellent pediatric surgeon and artist. During the September Campaign he took part in the battle of Bzura and in the defense of Polish capital as the physician in the 25th Regiment of Artillery. In 1940 he joined Polish underground army--AK. In 1944, when the Warsaw Uprising broke out, he was the Commander of the insurgent hospital--Poznańska 11. It was a very well arranged and headed hospital, which admitted about eight hundred wounded soldiers and civilians. After the war for two years he lived in Sopot, where he organized and directed the Surgery Hospital and the Town Outpatients' Department. In 1947 he moved to Szczecin, where he arranged the first ward of pediatric surgery in West Pomerania (in Polish Red Cross hospital). Ten years later he was nominated the head of the Clinic of Pediatric Surgery in the Pomeranian Medical Academy in Szczecin. For many years Prof. Drescher was provincial and regional consultant. He helped to organize a few pediatric surgery wards in Pomerania (Koszalin, Gorzów Wlkp., Słupsk). He died in 1977 in Warsaw. Prof. Drescher published almost 80 scientific papers including two medical books. Traumatology of children and the newborn surgery became his principal area of interest. He was the author of Code of the Ethical and Moral Procedure of the Polish Medical Society. For almost twenty years he was co-author the Annales of Pomeranian Medical Academy. He was a co-founder, next was a president of the Polish Association of

  17. Evaluating cumulative effects of anthropogenic inputs in Prince Edward Island estuaries using the mummichog (Fundulus heteroclitus).

    PubMed

    Finley, Megan A; Courtenay, Simon C; Teather, Kevin L; Hewitt, L Mark; Holdway, D A; Hogan, Natacha S; van den Heuvel, Michael R

    2013-07-01

    Estuarine eutrophication as a result of agricultural land use, including the use of chemical fertilizers, is increasing worldwide. Prince Edward Island (PEI), Canada has very high agricultural intensity by international standards with approximately 44% of the land area under production, and some watersheds in excess of 75% agricultural land-use. The type of agriculture is also intensive with primarily row crops that have high chemical fertilizer and pesticide usage. In light of these stressors, the hypothesis of this study was that mummichog (Fundulus heteroclitus) population parameters would change with point and nonpoint source pollution, and that multivariate statistics could be used to draw associations with specific stressors. Fish were sampled on a monthly basis from May through August at 7 estuaries spanning a range of land use, nutrient, and contaminant loadings. A suite of environmental variables were simplified into 3 principal components: PC1 representing agricultural land use, N loading, and plant habitat, PC2 being dominated by sediment sand and silt distribution, and PC3 largely reflecting P loading and sediment organic matter. There were significant differences in abundance of both adult and young-of-the-year mummichog, and these changes associated most strongly with PC1, the largely N-driven agricultural influences. In contrast, somatic variables such as liver and gonad size did not show strong association with the environmental quality principal component scores. The sand and silt PC2 appeared to have the opposite association with the biological data, with siltier environments correlating to older, larger, less dense populations of mummichog. Although pesticide residues were detected in estuarine sediment, there was no clear relationship between these and watershed agricultural intensity or biochemical indicators. There was, however, a strong relationship between agricultural environmental variables (PC1) and in vitro steroid production that is

  18. Evaluating cumulative effects of anthropogenic inputs in Prince Edward Island estuaries using the mummichog (Fundulus heteroclitus).

    PubMed

    Finley, Megan A; Courtenay, Simon C; Teather, Kevin L; Hewitt, L Mark; Holdway, D A; Hogan, Natacha S; van den Heuvel, Michael R

    2013-07-01

    Estuarine eutrophication as a result of agricultural land use, including the use of chemical fertilizers, is increasing worldwide. Prince Edward Island (PEI), Canada has very high agricultural intensity by international standards with approximately 44% of the land area under production, and some watersheds in excess of 75% agricultural land-use. The type of agriculture is also intensive with primarily row crops that have high chemical fertilizer and pesticide usage. In light of these stressors, the hypothesis of this study was that mummichog (Fundulus heteroclitus) population parameters would change with point and nonpoint source pollution, and that multivariate statistics could be used to draw associations with specific stressors. Fish were sampled on a monthly basis from May through August at 7 estuaries spanning a range of land use, nutrient, and contaminant loadings. A suite of environmental variables were simplified into 3 principal components: PC1 representing agricultural land use, N loading, and plant habitat, PC2 being dominated by sediment sand and silt distribution, and PC3 largely reflecting P loading and sediment organic matter. There were significant differences in abundance of both adult and young-of-the-year mummichog, and these changes associated most strongly with PC1, the largely N-driven agricultural influences. In contrast, somatic variables such as liver and gonad size did not show strong association with the environmental quality principal component scores. The sand and silt PC2 appeared to have the opposite association with the biological data, with siltier environments correlating to older, larger, less dense populations of mummichog. Although pesticide residues were detected in estuarine sediment, there was no clear relationship between these and watershed agricultural intensity or biochemical indicators. There was, however, a strong relationship between agricultural environmental variables (PC1) and in vitro steroid production that is

  19. Statistical Short-Range Guidance for Peak Wind Speed Forecasts at Edwards Air Force Base, CA

    NASA Technical Reports Server (NTRS)

    Dreher, Joseph; Crawford, Winifred; Lafosse, Richard; Hoeth, Brian; Burns, Kerry

    2008-01-01

    The peak winds near the surface are an important forecast element for Space Shuttle landings. As defined in the Shuttle Flight Rules (FRs), there are peak wind thresholds that cannot be exceeded in order to ensure the safety of the shuttle during landing operations. The National Weather Service Spaceflight Meteorology Group (SMG) is responsible for weather forecasts for all shuttle landings. They indicate peak winds are a challenging parameter to forecast. To alleviate the difficulty in making such wind forecasts, the Applied Meteorology Unit (AMTJ) developed a personal computer based graphical user interface (GUI) for displaying peak wind climatology and probabilities of exceeding peak-wind thresholds for the Shuttle Landing Facility (SLF) at Kennedy Space Center. However, the shuttle must land at Edwards Air Force Base (EAFB) in southern California when weather conditions at Kennedy Space Center in Florida are not acceptable, so SMG forecasters requested that a similar tool be developed for EAFB. Marshall Space Flight Center (MSFC) personnel archived and performed quality control of 2-minute average and 10-minute peak wind speeds at each tower adjacent to the main runway at EAFB from 1997- 2004. They calculated wind climatologies and probabilities of average peak wind occurrence based on the average speed. The climatologies were calculated for each tower and month, and were stratified by hour, direction, and direction/hour. For the probabilities of peak wind occurrence, MSFC calculated empirical and modeled probabilities of meeting or exceeding specific 10-minute peak wind speeds using probability density functions. The AMU obtained and reformatted the data into Microsoft Excel PivotTables, which allows users to display different values with point-click-drag techniques. The GUT was then created from the PivotTables using Visual Basic for Applications code. The GUI is run through a macro within Microsoft Excel and allows forecasters to quickly display and

  20. [Edward Wilhelm Drescher--the founder of pediatric surgery in West Pomerania].

    PubMed

    Pacanowski, J H

    1999-01-01

    Professor Edward Wilhelm Drescher--an eminent Polish pediatric surgeon and pioneer of this specialization in West Pomerania--was born in 1912 in Biłgoraj. His young years he spent in his parents familial town Kalisz, where he attended a very famous college--State Humanistic Grammar-School. In 1937 he graduated from Faculty of Medicine at the Warsaw University. Next year he started his career as a surgeon in the Surgery at Orthopedic Ward of Pediatric Clinic in Warsaw, which was directed by prof. Jan Kossakowski--excellent pediatric surgeon and artist. During the September Campaign he took part in the battle of Bzura and in the defense of Polish capital as the physician in the 25th Regiment of Artillery. In 1940 he joined Polish underground army--AK. In 1944, when the Warsaw Uprising broke out, he was the Commander of the insurgent hospital--Poznańska 11. It was a very well arranged and headed hospital, which admitted about eight hundred wounded soldiers and civilians. After the war for two years he lived in Sopot, where he organized and directed the Surgery Hospital and the Town Outpatients' Department. In 1947 he moved to Szczecin, where he arranged the first ward of pediatric surgery in West Pomerania (in Polish Red Cross hospital). Ten years later he was nominated the head of the Clinic of Pediatric Surgery in the Pomeranian Medical Academy in Szczecin. For many years Prof. Drescher was provincial and regional consultant. He helped to organize a few pediatric surgery wards in Pomerania (Koszalin, Gorzów Wlkp., Słupsk). He died in 1977 in Warsaw. Prof. Drescher published almost 80 scientific papers including two medical books. Traumatology of children and the newborn surgery became his principal area of interest. He was the author of Code of the Ethical and Moral Procedure of the Polish Medical Society. For almost twenty years he was co-author the Annales of Pomeranian Medical Academy. He was a co-founder, next was a president of the Polish Association of

  1. A Biography of Distinguished Scientist Gilbert Newton Lewis (by Edward S. Lewis)

    NASA Astrophysics Data System (ADS)

    Harris, Reviewed By Harold H.

    1999-11-01

    The Edward Mellen Press: Lewiston, NY, 1998. 114 pp + index. ISBN 0-7734-8284-9. $69.95. There may not be a surname better known to students of chemistry than Lewis, from the Lewis electron-dot diagrams and the Lewis theory of acids and bases. More advanced students may know of the groundbreaking textbook Thermodynamics, by Lewis and Randall. Yet few Americans know much about this remarkable U.S.-born scholar, whose contributions equal those of the greatest scientists. He is a chemist-educator of whom we should be as proud and as well informed as we are of Linus Pauling, who was part of the westward movement of science in this country that G. N. Lewis began, or of the recently deceased Glenn Seaborg, who was one of the many students of Lewis who achieved renown. Gilbert N. Lewis was born in Weymouth, Massachusetts, in 1875, but his family moved to near Lincoln, Nebraska, in 1884. He spent two years at the University of Nebraska, but then moved to Harvard when his father became an executive at Merchants Trust Company in Boston. Young Lewis (then only 17) was also said to have been disappointed with the quality of education in Nebraska, and this may have been part of the impetus for the family's move east. After earning his baccalaureate at Harvard, he taught for a year at Phillips Andover Academy before returning to Harvard to study for his doctorate, which he completed 100 years ago, in 1899, under T. W. Richards. Lewis's doctoral work was on the thermodynamics of zinc and cadmium amalgams. At that time, physical chemistry was only beginning to achieve recognition as a branch of science, and its boundaries were ill defined. Edward Lewis quotes his father as often saying, "Physical chemistry is anything interesting." Like many chemists of his time, Lewis went to Europe to complete his preparation for a career; he was in the laboratories of Ostwald in Leipzig and Nernst in Göttingen in 1900-1901. On his return to the United States, he was an instructor at Harvard

  2. STS-76 Landing - Space Shuttle Atlantis Lands at Edwards Air Force Base, Drag Chute Deploy

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The space shuttle Atlantis touches down on the runway at Edwards, California, at approximately 5:29 a.m. Pacific Standard Time after completing the highly successful STS-76 mission to deliver Astronaut Shannon Lucid to the Russian Space Station Mir. She was the first American woman to serve as a Mir station researcher. Atlantis was originally scheduled to land at Kennedy Space Center, Florida, but bad weather there both 30 and 31 March necessitated a landing at the backup site at Edwards. This photo shows the drag chute deployed to help the shuttle roll to a stop. Mission commander for STS-76 was Kevin P. Chilton, and Richard A. Searfoss was the pilot. Ronald M. Sega was payload commander and mission specialist-1. Mission specialists were Richard Clifford, Linda Godwin and Shannon Lucid. The mission also featured a spacewalk while Atlantis was docked to Mir and experiments aboard the SPACEHAB module. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be

  3. STS-76 Landing - Space Shuttle Atlantis Lands at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The space shuttle Atlantis prepares to touch down on the runway at Edwards, California, at approximately 5:29 a.m. Pacific Standard Time after completing the highly successful STS-76 mission to deliver Astronaut Shannon Lucid to the Russian Space Station Mir. Lucid was the first American woman to serve as a Mir station researcher. Atlantis was originally scheduled to land at Kennedy Space Center, Florida, but bad weather there both 30 March and 31 March necessitated a landing at the backup site at Edwards on the latter date. Mission commander for STS-76 was Kevin P. Chilton, and Richard A. Searfoss was the pilot. Ronald M. Sega was the payload commander and mission specialist-1. Other mission specialists were Richard Clifford, Linda Godwin, and Shannon Lucid. The mission also featured a spacewalk while Atlantis was docked to Mir and experiments aboard the SPACEHAB module. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they can only be used once. Space Shuttles are

  4. STS-76 Landing - Space Shuttle Atlantis Lands at Edwards Air Force Base

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The space shuttle Atlantis touches down on the runway at Edwards, California, at approximately 5:29 a.m. Pacific Standard Time on 31 March 1996 after completing the highly successful STS-76 mission to deliver Astronaut Shannon Lucid to the Russian Space Station Mir. She was the first American woman to serve as a Mir station researcher. Atlantis was originally scheduled to land at Kennedy Space Center, Florida, but bad weather there both March 30 and March 31 necessitated a landing at the backup site at Edwards AFB. Mission commander for STS-76 was Kevin P. Chilton. Richard A. Searfoss was the pilot. Serving as payload commander and mission specialist-1 was Ronald M. Sega. Mission specialist-2 was Richard Clifford. Linda Godwin served as mission specialist-3, and Shannon Lucid was mission specialist-4. The mission also featured a spacewalk while Atlantis was docked to Mir and experiments aboard the SPACEHAB module. Space Shuttles are the main element of America's Space Transportation System and are used for space research and other space applications. The shuttles are the first vehicles capable of being launched into space and returning to Earth on a routine basis. Space Shuttles are used as orbiting laboratories in which scientists and mission specialists conduct a wide variety of scientific experiments. Crews aboard shuttles place satellites in orbit, rendezvous with satellites to carry out repair missions and return them to space, and retrieve satellites and return them to Earth for refurbishment and reuse. Space Shuttles are true aerospace vehicles. They leave Earth and its atmosphere under rocket power provided by three liquid-propellant main engines with two solid-propellant boosters attached plus an external liquid-fuel tank. After their orbital missions, they streak back through the atmosphere and land like airplanes. The returning shuttles, however, land like gliders, without power and on runways. Other rockets can place heavy payloads into orbit, but, they

  5. Pagurus Asper H. Milne Edwards, 1848, a subjective synonym of Clibanarius longitarsus (De Haan, 1849) and reversal of precedence (Crustacea: Decapoda: Anomura: Diogenidae).

    PubMed

    Low, Martyn E Y; Rahayu, Dwi Listyo

    2014-01-01

    The species-group name Pagurus longitarsus was proposed by De Haan (1849: 211, pl. 50, fig. 3) for a species of hermit crab collected from Japan (see Yamaguchi & Baba 1993: 272, 273). Dana (1852b: 464) transferred Pagurus longitarsus to the genus Clibanarius Dana, 1852 (first established in Dana 1852a). Dana (1852b: 464) also suggested that Pagurus longitarsus De Haan, 1849, and Pagurus asper H. Milne Edwards, 1848, were possibly synonymous by listing "Pagurus asper ? Edwards, Ann. des Sci. Nat., 1848(3), v. [sic] 62" in the synonymy of Pagurus longitarsus De Haan, 1849. Fize & Serène (1955: 72) repeated Dana's (1852b: 464) opinion regarding the synonymy Pagurus longitarsus and Pagurus asper. McLaughlin (2002: 399) and McLaughlin et al. (2010: 20) also considered Pagurus longitarsus De Haan, 1849, and Pagurus asper H. Milne Edwards, 1848, to be possibly conspecific, but considered Clibanarius longitarsus (De Haan, 1849), to be the valid name.

  6. Compilation of hydrologic data for the Edwards Aquifer, San Antonio area, Texas, 1981, with 1934-81 summary

    USGS Publications Warehouse

    Reeves, R.D.; Maclay, R.W.; Ozuna, G.B.

    1984-01-01

    The average annual ground-water recharge to the Edwards aquifer in the San Antonio area, Texas, from 1934 through 1981, was 612,400 acre-feet. The recharge in 1981 was 1,448,400 acre-feet, which is the third highest annual recharge since 1934. A maximum annual recharge of 1,711,200 acre-feet occurred in 1958, and a minimum annual recharge of 43,700 acre-feet occurred in 1956. The calculated annual discharge by wells and springs in 1981 was 794,400 acre-feet. Annual discharge by wells and springs ranged from a maximum of 960,900 acre-feet in 1977 to a minimum of 388,800 acre-feet in 1955. The annual discharge by wells was 387,100 acre-feet in 1981. Although water levels in many of the wells in the Edwards aquifer fluctuated near the midpoint between record high and low levels during the first 5 months of 1981, the volume of ground water in storage in the aquifer was above average for most of the year. Analyses of water samples from 56 wells and 3 springs show that the water is of a significantly better quality than the level established for public water systems.

  7. Accuracy of non-invasive prenatal testing using cell-free DNA for detection of Down, Edwards and Patau syndromes: a systematic review and meta-analysis

    PubMed Central

    Taylor-Phillips, Sian; Freeman, Karoline; Geppert, Julia; Agbebiyi, Adeola; Uthman, Olalekan A; Madan, Jason; Clarke, Angus; Quenby, Siobhan; Clarke, Aileen

    2016-01-01

    Objective To measure test accuracy of non-invasive prenatal testing (NIPT) for Down, Edwards and Patau syndromes using cell-free fetal DNA and identify factors affecting accuracy. Design Systematic review and meta-analysis of published studies. Data sources PubMed, Ovid Medline, Ovid Embase and the Cochrane Library published from 1997 to 9 February 2015, followed by weekly autoalerts until 1 April 2015. Eligibility criteria for selecting studies English language journal articles describing case–control studies with ≥15 trisomy cases or cohort studies with ≥50 pregnant women who had been given NIPT and a reference standard. Results 41, 37 and 30 studies of 2012 publications retrieved were included in the review for Down, Edwards and Patau syndromes. Quality appraisal identified high risk of bias in included studies, funnel plots showed evidence of publication bias. Pooled sensitivity was 99.3% (95% CI 98.9% to 99.6%) for Down, 97.4% (95.8% to 98.4%) for Edwards, and 97.4% (86.1% to 99.6%) for Patau syndrome. The pooled specificity was 99.9% (99.9% to 100%) for all three trisomies. In 100 000 pregnancies in the general obstetric population we would expect 417, 89 and 40 cases of Downs, Edwards and Patau syndromes to be detected by NIPT, with 94, 154 and 42 false positive results. Sensitivity was lower in twin than singleton pregnancies, reduced by 9% for Down, 28% for Edwards and 22% for Patau syndrome. Pooled sensitivity was also lower in the first trimester of pregnancy, in studies in the general obstetric population, and in cohort studies with consecutive enrolment. Conclusions NIPT using cell-free fetal DNA has very high sensitivity and specificity for Down syndrome, with slightly lower sensitivity for Edwards and Patau syndrome. However, it is not 100% accurate and should not be used as a final diagnosis for positive cases. Trial registration number CRD42014014947. PMID:26781507

  8. Assessing the vulnerability of public-supply wells to contamination—Edwards aquifer near San Antonio, Texas

    USGS Publications Warehouse

    Jagucki, Martha L.; Musgrove, MaryLynn; Lindgren, Richard J.; Fahlquist, Lynne; Eberts, Sandra M.

    2011-01-01

    This fact sheet highlights findings from the vulnerability study of a public-supply well field in San Antonio, Texas. The well field consists of six production wells that tap the Edwards aquifer. Typically, one or two wells are pumped at a time, yielding an average total of 20-21 million gallons per day. Water samples were collected from public-supply wells in the well field and from monitoring wells installed along general directions of flow to the well field. Samples from the well field contained some constituents of concern for drinking-water quality, including nitrate; the pesticide compounds atrazine, deethylatrazine, and simazine; and the volatile organic compounds tetrachloroethene (also called perchloroethene, or PCE), chloroform, bromoform, and dibromochloromethane. These constituents were detected in untreated water at concentrations much less than established drinking-water standards, where such standards exist. Overall, the study findings point to four primary factors that affect the movement and fate of contaminants and the vulnerability of the public-supply well field in San Antonio, Texas: (1) groundwater age (how long ago water entered, or recharged, the aquifer), (2) fast pathways for flow of groundwater through features formed or enlarged by dissolution of bedrock, (3) recharge characteristics of the aquifer, and (4) natural geochemical processes within the aquifer. A computer-model simulation of groundwater flow and transport was used to estimate the traveltime (or age) of water particles entering public-supply well W4 in the well field. Modeled findings show that almost half of the water reaching the public-supply well is less than 2 years old. Such a large percentage of very young water indicates that (1) contaminants entering the aquifer may be transported rapidly to the well, (2) there is limited time for chemical reactions to occur in the aquifer that may attenuate contaminants, and (3) should recharge water become contaminated with

  9. High crystallizability under air-exclusion conditions of the full-length LysR-type transcriptional regulator TsaR from Comamonas testosteroni T-2 and data-set analysis for a MIRAS structure-solution approach

    PubMed Central

    Monferrer, Dominique; Tralau, Tewes; Kertesz, Michael A.; Panjikar, Santosh; Usón, Isabel

    2008-01-01

    The full-length LysR-type transcriptional regulator TsaR from Comamonas testosteroni T-2 was heterologously overexpressed in Escherichia coli, purified and stabilized under conditions that favoured its rapid crystallization using the microbatch-under-oil technique. The purified protein was highly crystallizable and two different crystal forms were readily obtained. However, only monoclinic crystals gave diffraction beyond 2 Å and there was a slight variation in unit-cell parameters between crystals. The only other LysR-type regulator for which a full-length crystal form is available is CbnR, but no solution could be obtained when this was used as a model in molecular replacement. Mercury and xenon derivatives were therefore produced in order to phase the structure using a MIRAS approach. PMID:18678953

  10. Soil Flushing Through a Thick Vadose Zone: Perchlorate Removal Documented at Edwards AFB, California

    NASA Astrophysics Data System (ADS)

    Battey, T. F.; Shepard, A. J.; Tait, R. J.

    2007-12-01

    There are currently few viable alternatives for perchlorate remediation in the vadose zone, particularly for the relatively thick vadose zones that are typical in the arid southwest where many perchlorate sites occur. Perchlorate in the vadose zone occurs in the form of highly soluble salts that may represent a risk to human or ecological receptors, and may also represent a threat to the underlying groundwater. A soil flushing treatability study was conducted at Edwards Air Force Base in the Mojave Desert of southern California at a site with a 129-foot thick vadose zone consisting primarily of clayey sand. This study utilized an infiltration gallery in conjunction with extraction, treatment, and re-injection of groundwater at the site, which contained perchlorate-contaminated soil and groundwater. The study objective was to evaluate the effectiveness of the infiltration gallery to 1) introduce treated groundwater back into the aquifer and 2) wash the perchlorate from the vadose zone soils to the aquifer. The infiltration gallery consisted of slotted PVC pipes within a highly permeable engineered bed of washed gravel. The initial water introduced into the gallery was amended with potassium bromide tracer. A downhole neutron probe was used to track the movement of the wetting front downward and outward from the gallery. Successive neutron measurements in vertical access tubes revealed that the introduced water reached the 125-foot bottom of the access tubes 14 weeks after the water was introduced into the gallery. The bromide tracer was detected in groundwater immediately below the gallery approximately 1 week later. The infiltration gallery was able to sustain an average flow rate of 2.3 gallons per minute. Prior to infiltration, the perchlorate concentration in groundwater below the gallery was 4,500 µg/L. Approximately 18 weeks after the start of infiltration, a perchlorate spike of 72,400 µg/L was detected below the gallery. The increase in perchlorate

  11. Predicting nitrate concentrations of groundwater from land uses in Prince Edward Island, Canada

    NASA Astrophysics Data System (ADS)

    Jiang, Y.; Chow, L.; Xing, Z.

    2009-05-01

    Elevated nitrate levels in groundwater are of growing concern for drinking water protection in Prince Edward Island (PEI). Elevated nitrate levels were identified being associated with the intensity of potato production. This study examined the relationship between land uses and nitrate levels in groundwater in PEI. A land use analysis was performed for each watershed (totaling 52) on PEI. Land uses in each watershed were categorized as A) agriculture and B) non-agriculture, and acreage for each category was calculated based on data of 1990. Category A was further subdivided into A1) land in potato production rotation and A2) pasture/grass based on data of period 1996-2000. Rotation lengths for Category A1 were also computed using GIS. LEACHM-N simulations, tile drain measurements, field N budgets and groundwater modeling were employed to define annual nitrate leaching to groundwater for each land use category, which was used to develop acreage-weighted nitrate leaching concentration of a watershed. With an assumption that the acreage- weighted nitrate concentration equal to mean nitrate concentration of well water, percentage of well water samples with nitrate level > 10 mg N/l was predicted based on a normal distribution derived from a statistics of well water samples. Mean nitrate concentration of well water in each watershed was calculated based on regular sample submissions to PEI Department of Environment during 2004-2008 (9512 samples) and compared against the acreage-weighted nitrate concentration based on current land use practice (assumed as the same of the year 20000). Acreage-weighted nitrate concentrations for a scenario of potato land to be adjusted to 3-yr rotation with a reduction of N rate on potato crop were used to predict the potential effects on nitrate reductions. The study showed mean nitrate level of well water appeared to be positively correlated with percentage of land used for potato production rotation in a watershed. Predicted acreage

  12. Special issue dedicated in memory of Dr. Edward H. Ahrens, Jr.

    PubMed

    Ahrens, Edward H

    2002-01-01

    This special issue of the "Cardiovascular Drug Reviews" is dedicated in memory of Dr. Edward H. Ahrens, Jr., who died on Dec. 9th, 2000 at the Princeton Medical Center in New Jersey at the age of 85. Dr. Ahrens was the Director of the Lipid Metabolism Laboratory at the Rockefeller University. Dr. Alexander Scriabine conceived the idea for the issue at the special memorial symposium held at the Rockefeller University on Feb. 05, 2002 under the auspices of The New York Lipid and Vascular Biology Research Club. Dr. Ahrens was the first president of the club. He started this club with Drs. Howard Eder and DeWitt Goodman. Dr. Eder thought that it would be a fitting attribute to honor one of the founding fathers of the club by hosting a memorial symposium. I, as the President of the club for that academic year, had no hesitation in accepting the proposal. This year will be the 40th anniversary of the club and its continued success provides a glimpse of the fine legacy left behind by Dr. Ahrens. Dr. Ahrens also played a pivotal role in the establishment of the Journal of Lipid Research. This is the 43rd year of the journal and in this commemorative issue we are reproducing a review he wrote for the 25th anniversary of the journal. I was never personally acquainted with Dr. Ahrens. However, I am honored that I got this opportunity to pay tribute to a great scientist whose work has contributed immensely to the progress of lipid research. He was a person who touched many lives and still continues to do so. My involvement in the remembrance of Dr. Ahrens shows that science not only impacts your contemporaries but also generations that follow you. Scientific research is a journey where you can leave your trails behind and be remembered for your work long after your departure from this world. Dr. Ahrens contributed immensely to the understanding of cholesterol metabolism. In the early stages of his career he showed that phospholipids solubilize fat in the blood. Now we know

  13. Response to Edwards' comments on Origin of British and Irish mammals: disparate post-glacial colonisation and species introductions

    NASA Astrophysics Data System (ADS)

    Montgomery, W. I.; Provan, J.

    2014-12-01

    We are most grateful to Dr Edwards for her lucid summary of recent, calibrated dates for giant Irish deer, red deer, reindeer and brown bear in Irish deposits during the period before and after the Last Glacial Maximum (LGM). Montgomery et al. (2014) dealt largely with the period after the LGM because the physical evidence suggests Ireland was completely covered by ice for at least part of the period between 28 ka and 23 ka (Clark et al., 2012; O'Cofaigh et al., 2012) when Ireland would not have supported any terrestrial mammals. The earliest it was possible for re-colonisation of these species to occur after LGM was probably during the rapid retreat of ice after 23 ka and before 15 ka when the Irish Sea became a complete barrier to terrestrial mammals between Britain and Ireland. There are no dates for any of the four species during the LGM and only one for giant Irish deer (BM-1794, date 18,761-18,034 cal. BP) which is from a site close to the present coast just south of Dublin, between LGM and completion of the Irish Sea, suggesting that conditions generally remained unsuitable for even cold-adapted mammals for many millennia after LGM. Edwards (2014) indicates clearly that all four species are well represented after Ireland became an island although giant Irish deer struggle to make it into the Holocene and the red deer record is broken and perhaps influenced by people (Carden et al., 2012). The sudden reappearance of large mammals around 13-15 ka is consistent with re-colonisation from cryptic refugia lying to the south and west of present day Ireland. The relatively short periods of warming and cooling during the Older and Younger Dryas respectively, followed by warming in the Holocene and the arrival of Mesolithic and Neolithic people remain the major events in the history of Irish mammals until the late 19th Century to the present during which many mammals species have been introduced (Montgomery et al., 2014). Whilst events prior to the LGM are important

  14. Shaping America's Future III: Proceedings of the National Forum on Transforming Our System of Educating Youth with W. Edwards Deming (June 8, 1992).

    ERIC Educational Resources Information Center

    National Educational Service, Bloomington, IN.

    On June 8, 1992, the presidents of the nation's two largest teachers unions joined the directors and presidents of virtually every educational organization, as well as political leaders and executives from Ford, General Motors, and Chrysler in an effort to redesign U.S. schools using the quality principles of W. Edwards Deming. Panelists spent the…

  15. How Direct Descendants of a School Lockout Achieved Academic Success: Resilience in the Educational Attainments of Prince Edward County's Children

    ERIC Educational Resources Information Center

    Williams, Randolph, Jr.

    2013-01-01

    From 1959 to 1964, approximately 1,700 Black children in Prince Edward County, Virginia were denied schooling, due to the county leaders' decision to close schools--a defiant response to federal racial desegregation mandates stemming from "Brown v. Board of Education" (1954, 1955). Yet from one of the most extreme cases of injustice…

  16. Youth Speaks ... P.E.I. Listens! Young Leaders' Forum 2007. Rural Dialogue Summary Report (Charlottetown, Prince Edward Island, Canada, March 9-10, 2007)

    ERIC Educational Resources Information Center

    Canadian Rural Partnership, 2007

    2007-01-01

    This report is a summary of discussions that took place at the Young Leaders' Forum held in Charlottetown, Prince Edward Island (PEI), on March 9-10, 2007. The event was part of the Rural Dialogue, an on-going, two-way discussion between the Government of Canada and Canadians from rural, remote and northern regions. Launched in 1998, the Rural…

  17. Quality of stormwater runoff from an urbanizing watershed and a rangeland watershed in the Edwards aquifer recharge zone, Bexar and Uvalde counties, Texas, 1996-98

    USGS Publications Warehouse

    Ging, P.B.

    1999-01-01

    Encroachment of urban development on the outcrop of the Edwards aquifer (the recharge zone), particularly in Bexar County, has raised the issue of possible contamination of water that enters the aquifer. Increasing residential and commercial development on the recharge zone increases the potential for runoff containing toxic substances, oil spills, or leakage of hazardous materials to contaminate the regional drinking water supply.

  18. The Reality of Aging Viewed from the Arterial Wall: An Interview with Dr. Edward Lakatta, Founder and Director of the Laboratory of Cardiovascular Science, National Institute on Aging.

    PubMed

    Park, Jeong Bae; Park, Sungha

    2013-10-01

    An exclusive interview conducted by Professors Jeong Bae Park and Sungha Park with Dr. Edward Lakatta in Seoul while he was visiting for the Pulse of Asia 2013 in Seoul. In this interview, Dr. Lakatta explains and describes vascular aging and aging.

  19. Pedagogy of the Other: Edward Said, Postcolonial Theory, and Strategies for Critique. Counterpoints: Studies in the Postmodern Theory of Education. Volume 417

    ERIC Educational Resources Information Center

    Burney, Shehla

    2012-01-01

    Edward Said has been acknowledged as one of the greatest critics and cultural theorists of our time. His groundbreaking work "Orientalism" initiated the development of postcolonial theory, causing a paradigm shift by re-conceptualizing, deconstructing, and re-presenting the "Orient" as the ultimate "Other" of the "Occident." Despite its influence…

  20. Biaxial deformation of a polymer under shear: NMR test of the Doi-Edwards model with convected constraint release

    NASA Astrophysics Data System (ADS)

    Cormier, Ryan J.; Kilfoil, Maria L.; Callaghan, Paul T.

    2001-11-01

    2H NMR quadrupole interaction spectroscopy has been used to measure the deformation of a 670 kD poly(dimethylsiloxane) melt under shear in a Couette cell. The signals were acquired from a per deuterated benzene probe molecule which provides a motionally averaged sampling of the entire segmental ensemble. We have measured the dependence on shear rate of the SXX (velocity), SYY (velocity gradient), SZZ (vorticity), and SXY (shear) elements of the segmental alignment tensor, as well as the angular dependence of the deuterium quadrupole splitting at fixed shear rate. We show that the data agree quite well with the Doi-Edwards theory but significantly better when convected constraint release effects are included. These fits return a value for the tube disengagement time of 100 ms.