Heavy-light mesons in chiral AdS/QCD

NASA Astrophysics Data System (ADS)

Liu, Yizhuang; Zahed, Ismail

2017-06-01

We discuss a minimal holographic model for the description of heavy-light and light mesons with chiral symmetry, defined in a slab of AdS space. The model consists of a pair of chiral Yang-Mills and tachyon fields with specific boundary conditions that break spontaneously chiral symmetry in the infrared. The heavy-light spectrum and decay constants are evaluated explicitly. In the heavy mass limit the model exhibits both heavy-quark and chiral symmetry and allows for the explicit derivation of the one-pion axial couplings to the heavy-light mesons.

Chiral anomaly and anomalous finite-size conductivity in graphene

NASA Astrophysics Data System (ADS)

Shen, Shun-Qing; Li, Chang-An; Niu, Qian

2017-09-01

Graphene is a monolayer of carbon atoms packed into a hexagon lattice to host two spin degenerate pairs of massless two-dimensional Dirac fermions with different chirality. It is known that the existence of non-zero electric polarization in reduced momentum space which is associated with a hidden chiral symmetry will lead to the zero-energy flat band of a zigzag nanoribbon and some anomalous transport properties. Here it is proposed that the Adler-Bell-Jackiw chiral anomaly or non-conservation of chiral charges of Dirac fermions at different valleys can be realized in a confined ribbon of finite width, even in the absence of a magnetic field. In the laterally diffusive regime, the finite-size correction to conductivity is always positive and is inversely proportional to the square of the lateral dimension W, which is different from the finite-size correction inversely proportional to W from the boundary modes. This anomalous finite-size conductivity reveals the signature of the chiral anomaly in graphene, and it is measurable experimentally. This finding provides an alternative platform to explore the purely quantum mechanical effect in graphene.

Theory of Magnetic Edge States in Chiral Graphene Nanoribbons

NASA Astrophysics Data System (ADS)

Capaz, Rodrigo; Yazyev, Oleg; Louie, Steven

2011-03-01

Using a model Hamiltonian approach including electron Coulomb interactions, we systematically investigate the electronic structure and magnetic properties of chiral graphene nanoribbons. We show that the presence of magnetic edge states is an intrinsic feature of any smooth graphene nanoribbons with chiral edges, and discover a number of structure-property relations. Specifically, we describe how the edge-state energy gap, zone-boundary edge-state energy splitting, and magnetic moment per edge length depend on the nanoribbon width and chiral angle. The role of environmental screening effects is also studied. Our results address a recent experimental observation of signatures of magnetic ordering at smooth edges of chiral graphene nanoribbons and provide an avenue towards tuning their properties via the structural and environmental degrees of freedom. This work was supported by National Science Foundation Grant No. DMR10-1006184, the U.S. Department of Energy under Contract No. DE-AC02-05CH11231 and the ONR MURI program. RBC acknowledges financial support from Brazilian agencies CNPq, FAPERJ and INCT-Nanomateriais de Carbono.

Boundary stress tensor and asymptotically AdS3 non-Einstein spaces at the chiral point

NASA Astrophysics Data System (ADS)

Giribet, Gaston; Goya, Andrés; Leston, Mauricio

2011-09-01

Chiral gravity admits asymptotically AdS3 solutions that are not locally equivalent to AdS3; meaning that solutions do exist which, while obeying the strong boundary conditions usually imposed in general relativity, happen not to be Einstein spaces. In topologically massive gravity (TMG), the existence of non-Einstein solutions is particularly connected to the question about the role played by complex saddle points in the Euclidean path integral. Consequently, studying (the existence of) nonlocally AdS3 solutions to chiral gravity is relevant to understanding the quantum theory. Here, we discuss a special family of nonlocally AdS3 solutions to chiral gravity. In particular, we show that such solutions persist when one deforms the theory by adding the higher-curvature terms of the so-called new massive gravity. Moreover, the addition of higher-curvature terms to the gravity action introduces new nonlocally AdS3 solutions that have no analogues in TMG. Both stationary and time-dependent, axially symmetric solutions that asymptote AdS3 space without being locally equivalent to it appear. Defining the boundary stress tensor for the full theory, we show that these non-Einstein geometries have associated vanishing conserved charges.

Micropatterning of cells reveals chiral morphogenesis

PubMed Central

2013-01-01

Invariant left-right (LR) patterning or chirality is critical for embryonic development. The loss or reversal of LR asymmetry is often associated with malformations and disease. Although several theories have been proposed, the exact mechanism of the initiation of the LR symmetry has not yet been fully elucidated. Recently, chirality has been detected within single cells as well as multicellular structures using several in vitro approaches. These studies demonstrated the universality of cell chirality, its dependence on cell phenotype, and the role of physical boundaries. In this review, we discuss the theories for developmental LR asymmetry, compare various in vitro cell chirality model systems, and highlight possible roles of cell chirality in stem cell differentiation. We emphasize that the in vitro cell chirality systems have great promise for helping unveil the nature of chiral morphogenesis in development. PMID:23672821

Valley-chiral quantum Hall state in graphene superlattice structure

NASA Astrophysics Data System (ADS)

Tian, H. Y.; Tao, W. W.; Wang, J.; Cui, Y. H.; Xu, N.; Huang, B. B.; Luo, G. X.; Hao, Y. H.

2016-05-01

We theoretically investigate the quantum Hall effect in a graphene superlattice (GS) system, in which the two valleys of graphene are coupled together. In the presence of a perpendicular magnetic field, an ordinary quantum Hall effect is found with the sequence σxy=ν e^2/h(ν=0,+/-1,+/-2,\\cdots) . At the zeroth Hall platform, a valley-chiral Hall state stemming from the single K or K' valley is found and it is localized only on one sample boundary contributing to the longitudinal conductance but not to the Hall conductivity. Our findings may shed light on the graphene-based valleytronics applications.

Gapless edges of 2d topological orders and enriched monoidal categories

NASA Astrophysics Data System (ADS)

Kong, Liang; Zheng, Hao

2018-02-01

In this work, we give a mathematical description of a chiral gapless edge of a 2d topological order (without symmetry). We show that the observables on the 1+1D world sheet of such an edge consist of a family of topological edge excitations, boundary CFT's and walls between boundary CFT's. These observables can be described by a chiral algebra and an enriched monoidal category. This mathematical description automatically includes that of gapped edges as special cases. Therefore, it gives a unified framework to study both gapped and gapless edges. Moreover, the boundary-bulk duality also holds for gapless edges. More precisely, the unitary modular tensor category that describes the 2d bulk phase is exactly the Drinfeld center of the enriched monoidal category that describes the gapless/gapped edge. We propose a classification of all gapped and chiral gapless edges of a given bulk phase. In the end, we explain how modular-invariant bulk rational conformal field theories naturally emerge on certain gapless walls between two trivial phases.

Timoshenko beam model for chiral materials

NASA Astrophysics Data System (ADS)

Ma, T. Y.; Wang, Y. N.; Yuan, L.; Wang, J. S.; Qin, Q. H.

2017-12-01

Natural and artificial chiral materials such as deoxyribonucleic acid (DNA), chromatin fibers, flagellar filaments, chiral nanotubes, and chiral lattice materials widely exist. Due to the chirality of intricately helical or twisted microstructures, such materials hold great promise for use in diverse applications in smart sensors and actuators, force probes in biomedical engineering, structural elements for absorption of microwaves and elastic waves, etc. In this paper, a Timoshenko beam model for chiral materials is developed based on noncentrosymmetric micropolar elasticity theory. The governing equations and boundary conditions for a chiral beam problem are derived using the variational method and Hamilton's principle. The static bending and free vibration problem of a chiral beam are investigated using the proposed model. It is found that chirality can significantly affect the mechanical behavior of beams, making materials more flexible compared with nonchiral counterparts, inducing coupled twisting deformation, relatively larger deflection, and lower natural frequency. This study is helpful not only for understanding the mechanical behavior of chiral materials such as DNA and chromatin fibers and characterizing their mechanical properties, but also for the design of hierarchically structured chiral materials.

Timoshenko beam model for chiral materials

NASA Astrophysics Data System (ADS)

Ma, T. Y.; Wang, Y. N.; Yuan, L.; Wang, J. S.; Qin, Q. H.

2018-06-01

Natural and artificial chiral materials such as deoxyribonucleic acid (DNA), chromatin fibers, flagellar filaments, chiral nanotubes, and chiral lattice materials widely exist. Due to the chirality of intricately helical or twisted microstructures, such materials hold great promise for use in diverse applications in smart sensors and actuators, force probes in biomedical engineering, structural elements for absorption of microwaves and elastic waves, etc. In this paper, a Timoshenko beam model for chiral materials is developed based on noncentrosymmetric micropolar elasticity theory. The governing equations and boundary conditions for a chiral beam problem are derived using the variational method and Hamilton's principle. The static bending and free vibration problem of a chiral beam are investigated using the proposed model. It is found that chirality can significantly affect the mechanical behavior of beams, making materials more flexible compared with nonchiral counterparts, inducing coupled twisting deformation, relatively larger deflection, and lower natural frequency. This study is helpful not only for understanding the mechanical behavior of chiral materials such as DNA and chromatin fibers and characterizing their mechanical properties, but also for the design of hierarchically structured chiral materials.

Chiral Tricritical Point: A New Universality Class in Dirac Systems

NASA Astrophysics Data System (ADS)

Yin, Shuai; Jian, Shao-Kai; Yao, Hong

2018-05-01

Tricriticality, as a sister of criticality, is a fundamental and absorbing issue in condensed-matter physics. It has been verified that the bosonic Wilson-Fisher universality class can be changed by gapless fermionic modes at criticality. However, the counterpart phenomena at tricriticality have rarely been explored. In this Letter, we study a model in which a tricritical Ising model is coupled to massless Dirac fermions. We find that the massless Dirac fermions result in the emergence of a new tricritical point, which we refer to as the chiral tricritical point (CTP), at the phase boundary between the Dirac semimetal and the charge-density wave insulator. From functional renormalization group analysis of the effective action, we obtain the critical behaviors of the CTP, which are qualitatively distinct from both the tricritical Ising universality and the chiral Ising universality. We further extend the calculations of the chiral tricritical behaviors of Ising spins to the case of Heisenberg spins. The experimental relevance of the CTP in two-dimensional Dirac semimetals is also discussed.

Tweaking one-loop determinants in AdS3

NASA Astrophysics Data System (ADS)

Castro, Alejandra; Keeler, Cynthia; Szepietowski, Phillip

2017-10-01

We revisit the subject of one-loop determinants in AdS3 gravity via the quasi-normal mode method. Our goal is to evaluate a one-loop determinant with chiral boundary conditions for the metric field; chirality is achieved by imposing Dirichlet boundary conditions on certain components while others satisfy Neumann. Along the way, we give a generalization of the quasinormal mode method for stationary (non-static) thermal backgrounds, and propose a treatment for Neumann boundary conditions in this framework. We evaluate the graviton one-loop determinant on the Euclidean BTZ background with parity-violating boundary conditions (CSS), and find excellent agreement with the dual warped CFT. We also discuss a more general falloff in AdS3 that is related to two dimensional quantum gravity in lightcone gauge. The behavior of the ghost fields under both sets of boundary conditions is novel and we discuss potential interpretations.

Vector two-point functions in finite volume using partially quenched chiral perturbation theory at two loops

NASA Astrophysics Data System (ADS)

Bijnens, Johan; Relefors, Johan

2017-12-01

We calculate vector-vector correlation functions at two loops using partially quenched chiral perturbation theory including finite volume effects and twisted boundary conditions. We present expressions for the flavor neutral cases and the flavor charged case with equal masses. Using these expressions we give an estimate for the ratio of disconnected to connected contributions for the strange part of the electromagnetic current. We give numerical examples for the effects of partial quenching, finite volume and twisting and suggest the use of different twists to check the size of finite volume effects. The main use of this work is expected to be for lattice QCD calculations of the hadronic vacuum polarization contribution to the muon anomalous magnetic moment.

Comment on "Chiral gauge field and axial anomaly in a Weyl semimetal"

NASA Astrophysics Data System (ADS)

Zhang, Kai; Zhang, Erhu; Zhang, Shengli

2017-12-01

In Liu et al. [Phys. Rev. B 87, 235306 (2013), 10.1103/PhysRevB.87.235306], the authors obtain that the cross coupling between vector gauge field and chiral gauge field can lead to the anomaly of vector current. We demonstrate that this anomaly is not a physical effect. On one hand, it can be regulated out by the proper regulation. On the other hand, it leads to unjustifiable results, the breaking of the vector gauge symmetry and the ambiguous boundary current. Moreover, the effects associated with anomaly of vector current are understood by random phase approximation (RPA) in the paper we comment on. We point out that the RPA cannot describe the effects resulting from the quantum anomaly.

High-effective approach from amino acid esters to chiral amino alcohols over Cu/ZnO/Al2O3 catalyst and its catalytic reaction mechanism

NASA Astrophysics Data System (ADS)

Zhang, Shuangshuang; Yu, Jun; Li, Huiying; Mao, Dongsen; Lu, Guanzhong

2016-09-01

Developing the high-efficient and green synthetic method for chiral amino alcohols is an intriguing target. We have developed the Mg2+-doped Cu/ZnO/Al2O3 catalyst for hydrogenation of L-phenylalanine methyl ester to chiral L-phenylalaninol without racemization. The effect of different L-phenylalanine esters on this title reaction was studied, verifying that Cu/ZnO/Al2O3 is an excellent catalyst for the hydrogenation of amino acid esters to chiral amino alcohols. DFT calculation was used to study the adsorption of substrate on the catalyst, and showed that the substrate adsorbs on the surface active sites mainly by amino group (-NH2) absorbed on Al2O3, and carbonyl (C=O) and alkoxy (RO-) group oxygen absorbed on the boundary of Cu and Al2O3. This catalytic hydrogenation undergoes the formation of a hemiacetal intermediate and the cleavage of the C-O bond (rate-determining step) by reacting with dissociated H to obtain amino aldehyde and methanol ad-species. The former is further hydrogenated to amino alcohols, and the latter desorbs from the catalyst surface.

High-effective approach from amino acid esters to chiral amino alcohols over Cu/ZnO/Al2O3 catalyst and its catalytic reaction mechanism

PubMed Central

Zhang, Shuangshuang; Yu, Jun; Li, Huiying; Mao, Dongsen; Lu, Guanzhong

2016-01-01

Developing the high-efficient and green synthetic method for chiral amino alcohols is an intriguing target. We have developed the Mg2+-doped Cu/ZnO/Al2O3 catalyst for hydrogenation of L-phenylalanine methyl ester to chiral L-phenylalaninol without racemization. The effect of different L-phenylalanine esters on this title reaction was studied, verifying that Cu/ZnO/Al2O3 is an excellent catalyst for the hydrogenation of amino acid esters to chiral amino alcohols. DFT calculation was used to study the adsorption of substrate on the catalyst, and showed that the substrate adsorbs on the surface active sites mainly by amino group (-NH2) absorbed on Al2O3, and carbonyl (C=O) and alkoxy (RO-) group oxygen absorbed on the boundary of Cu and Al2O3. This catalytic hydrogenation undergoes the formation of a hemiacetal intermediate and the cleavage of the C–O bond (rate-determining step) by reacting with dissociated H to obtain amino aldehyde and methanol ad-species. The former is further hydrogenated to amino alcohols, and the latter desorbs from the catalyst surface. PMID:27619990

Open tubular capillary columns with basic templates made by the generalized preparation protocol in capillary electrochromatography chiral separation and template structural effects on chiral separation capability.

PubMed

Zaidi, Shabi Abbas; Lee, Seung Mi; Cheong, Won Jo

2011-03-04

Some open tubular (OT) molecule imprinted polymer (MIP) silica capillary columns have been prepared using atenolol, sulpiride, methyl benzylamine (MBA) and (1-naphthyl)-ethylamine (NEA) as templates by the pre-established generalized preparation protocol. The four MIP thin layers of different templates showed quite different morphologies. The racemic selectivity of each MIP column for the template enantiomers was optimized by changing eluent composition and pH. The template structural effects on chiral separation performance have been examined. This work verifies the versatility of the generalized preparation protocol for OT-MIP silica capillary columns by extending its boundary toward templates with basic functional group moieties. This study is the very first report to demonstrate a generalized MIP preparation protocol that is valid for both acidic and basic templates. The chiral separation performances of atenolol and sulpiride by the MIPs of this study were found better than or comparable to those of atenolol and sulpiride obtained by non-MIP separation techniques and those of some basic template enantiomers obtained by MIP based techniques. Copyright © 2011 Elsevier B.V. All rights reserved.

Exact equivalence of the D=4 gauged Wess-Zumino-Witten term and the D=5 Yang-Mills Chern-Simons term

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hill, Christopher T.

We derive the full Wess-Zumino-Witten term of a gauged chiral Lagrangian in D=4 by starting from a pure Yang-Mills theory of gauged quark flavor in a flat, compactified D=5. The theory is compactified such that there exists a B{sub 5} zero mode, and supplemented with quarks that are 'chirally delocalized' with q{sub L} (q{sub R}) on the left (right) boundary (brane). The theory then necessarily contains a Chern-Simons term (anomaly flux) to cancel the fermionic anomalies on the boundaries. The constituent quark mass represents chiral symmetry breaking and is a bilocal operator in D=5 of the form: q{sub L}Wq{sub R}+h.c,more » where W is the Wilson line spanning the bulk, 0{<=}x{sup 5}{<=}R, and is interpreted as a chiral meson field, W=exp(2i{pi}-tilde/f{sub {pi}}), where f{sub {pi}}{approx}1/R. The quarks are integrated out, yielding a Dirac determinant which takes the form of a 'boundary term' (anomaly flux return), and is equivalent to Bardeen's counterterm that connects consistent and covariant anomalies. The Wess-Zumino-Witten term then emerges straightforwardly, from the Yang-Mills Chern-Simons term, plus boundary term. The method is systematic and allows generalization of the Wess-Zumino-Witten term to theories of extra dimensions, and to express it in alternative and more compact forms. We give a novel form appropriate to the case of (unintegrated) massless fermions.« less

Mixing and demixing of binary mixtures of polar chiral active particles.

PubMed

Ai, Bao-Quan; Shao, Zhi-Gang; Zhong, Wei-Rong

2018-05-17

We study a binary mixture of polar chiral (counterclockwise or clockwise) active particles in a two-dimensional box with periodic boundary conditions. Besides the excluded volume interactions between particles, the particles are also subjected to the polar velocity alignment. From the extensive Brownian dynamics simulations, it is found that the particle configuration (mixing or demixing) is determined by the competition between the chirality difference and the polar velocity alignment. When the chirality difference competes with the polar velocity alignment, the clockwise particles aggregate in one cluster and the counterclockwise particles aggregate in the other cluster; thus, the particles are demixed and can be separated. However, when the chirality difference or the polar velocity alignment is dominant, the particles are mixed. Our findings could be used for the experimental pursuit of the separation of binary mixtures of chiral active particles.

Chiral topological insulating phases from three-dimensional nodal loop semimetals

NASA Astrophysics Data System (ADS)

Li, Linhu; Yin, Chuanhao; Chen, Shu; Araujo, Miguel

We begin with a minimal model of three-dimensional nodal loop semimetals, and study the effect of anticommuting gap terms. The resulting topological insulating phases are protected by a chiral symmetry, and can be characterized by a winding number defined along the nodal loop. We illustrate the geometric relation between the nodal loop and the gap terms, which has a correspondence to the nodal loop winding number. We further investigate a lattice model and study its edge states under open boundary condition. The edge states hold Dirac cones with the same number as the summation of the winding numbers of each nodal loop in the first Brillouin zone.

Bulk and boundary unitary gravity in 3D: MMG2

NASA Astrophysics Data System (ADS)

Tekin, Bayram

2015-07-01

We construct a massive spin-2 theory in 2 +1 dimensions that is immune to the bulk-boundary unitarity conflict in anti-de Sitter space and hence amenable to holography. The theory is an extension of topologically massive gravity (TMG), just like the recently found minimal massive gravity (MMG), but it has two massive helicity modes instead of a single one. The theory admits all the solutions of TMG with a redefined topological parameter. We calculate the Shapiro time delay and show that flat-space (local) causality is not violated. We show that there is an interesting relation between the theory we present here (which we call MMG2 ), MMG, and the earlier new massive gravity (NMG): namely, field equations of these theories are nontrivially related. We study the bulk excitations and boundary charges of the conformal field theory that could be dual to gravity. We also find the chiral gravity limit for which one of the massive modes becomes massless. The virtue of the model is that one does not have to go to the chiral limit to achieve unitarity in the bulk and on the boundary, and the log-terms that appear in the chiral limit and cause instability do not exist in the generic theory.

A quenched study of the Schrödinger functional with chirally rotated boundary conditions: Applications

NASA Astrophysics Data System (ADS)

González López, J.; Jansen, K.; Renner, D. B.; Shindler, A.

2013-02-01

In a previous paper (González López, et al., 2013) [1], we have discussed the non-perturbative tuning of the chirally rotated Schrödinger functional (χSF). This tuning is required to eliminate bulk O(a) cutoff effects in physical correlation functions. Using our tuning results obtained in González López et al. (2013) [1] we perform scaling and universality tests analyzing the residual O(a) cutoff effects of several step-scaling functions and we compute renormalization factors at the matching scale. As an example of possible application of the χSF we compute the renormalized strange quark mass using large volume data obtained from Wilson twisted mass fermions at maximal twist.

Left-right asymmetry is formed in individual cells by intrinsic cell chirality.

PubMed

Hatori, Ryo; Ando, Tadashi; Sasamura, Takeshi; Nakazawa, Naotaka; Nakamura, Mitsutoshi; Taniguchi, Kiichiro; Hozumi, Shunya; Kikuta, Junichi; Ishii, Masaru; Matsuno, Kenji

2014-08-01

Many animals show left-right (LR) asymmetric morphology. The mechanisms of LR asymmetric development are evolutionarily divergent, and they remain elusive in invertebrates. Various organs in Drosophila melanogaster show stereotypic LR asymmetry, including the embryonic gut. The Drosophila embryonic hindgut twists 90° left-handedly, thereby generating directional LR asymmetry. We recently revealed that the hindgut epithelial cell is chiral in shape and other properties; this is termed planar cell chirality (PCC). We previously showed by computer modeling that PCC is sufficient to induce the hindgut rotation. In addition, both the PCC and the direction of hindgut twisting are reversed in Myosin31DF (Myo31DF) mutants. Myo31DF encodes Drosophila MyosinID, an actin-based motor protein, whose molecular functions in LR asymmetric development are largely unknown. Here, to understand how PCC directs the asymmetric cell-shape, we analyzed PCC in genetic mosaics composed of cells homozygous for mutant Myo31DF, some of which also overexpressed wild-type Myo31DF. Wild-type cell-shape chirality only formed in the Myo31DF-overexpressing cells, suggesting that cell-shape chirality was established in each cell and reflects intrinsic PCC. A computer model recapitulating the development of this genetic mosaic suggested that mechanical interactions between cells are required for the cell-shape behavior seen in vivo. Our mosaic analysis also suggested that during hindgut rotation in vivo, wild-type Myo31DF suppresses the elongation of cell boundaries, supporting the idea that cell-shape chirality is an intrinsic property determined in each cell. However, the amount and distribution of F-actin and Myosin II, which are known to help generate the contraction force on cell boundaries, did not show differences between Myo31DF mutant cells and wild-type cells, suggesting that the static amount and distribution of these proteins are not involved in the suppression of cell-boundary elongation. Taken together, our results suggest that cell-shape chirality is intrinsically formed in each cell, and that mechanical force from intercellular interactions contributes to its formation and/or maintenance. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Active fluids at circular boundaries: swim pressure and anomalous droplet ripening.

PubMed

Jamali, Tayeb; Naji, Ali

2018-06-13

We investigate the swim pressure exerted by non-chiral and chiral active particles on convex or concave circular boundaries. Active particles are modeled as non-interacting and non-aligning self-propelled Brownian particles. The convex and concave circular boundaries are used to model a fixed inclusion immersed in an active bath and a cavity (or container) enclosing the active particles, respectively. We first present a detailed analysis of the role of convex versus concave boundary curvature and of the chirality of active particles in their spatial distribution, chirality-induced currents, and the swim pressure they exert on the bounding surfaces. The results will then be used to predict the mechanical equilibria of suspended fluid enclosures (generically referred to as 'droplets') in a bulk with active particles being present either inside the bulk fluid or within the suspended droplets. We show that, while droplets containing active particles behave in accordance with standard capillary paradigms when suspended in a normal bulk, those containing a normal fluid exhibit anomalous behaviors when suspended in an active bulk. In the latter case, the excess swim pressure results in non-monotonic dependence of the inside droplet pressure on the droplet radius; hence, revealing an anomalous regime of behavior beyond a threshold radius, in which the inside droplet pressure increases upon increasing the droplet size. Furthermore, for two interconnected droplets, mechanical equilibrium can occur also when the droplets have different sizes. We thus identify a regime of anomalous droplet ripening, where two unequal-sized droplets can reach a final state of equal size upon interconnection, in stark contrast with the standard Ostwald ripening phenomenon, implying shrinkage of the smaller droplet in favor of the larger one.

Edge states at phase boundaries and their stability

NASA Astrophysics Data System (ADS)

Asorey, M.; Balachandran, A. P.; Pérez-Pardo, J. M.

2016-10-01

We analyze the effects of Robin-like boundary conditions on different quantum field theories of spin 0, 1/2 and 1 on manifolds with boundaries. In particular, we show that these conditions often lead to the appearance of edge states. These states play a significant role in physical phenomena like quantum Hall effect and topological insulators. We prove in a rigorous way the existence of spectral lower bounds on the kinetic term of different Hamiltonians, even in the case of Abelian gauge fields where it is a non-elliptic differential operator. This guarantees the stability and consistency of massive field theories with masses larger than the lower bound of the kinetic term. Moreover, we find an upper bound for the deepest edge state. In the case of Abelian gauge theories, we analyze a generalization of Robin boundary conditions. For Dirac fermions, we analyze the cases of Atiyah-Patodi-Singer and chiral bag boundary conditions. The explicit dependence of the bounds on the boundary conditions and the size of the system is derived under general assumptions.

Structure of neutron star crusts from new Skyrme effective interactions constrained by chiral effective field theory

NASA Astrophysics Data System (ADS)

Lim, Yeunhwan; Holt, Jeremy W.

2017-06-01

We investigate the structure of neutron star crusts, including the crust-core boundary, based on new Skyrme mean field models constrained by the bulk-matter equation of state from chiral effective field theory and the ground-state energies of doubly-magic nuclei. Nuclear pasta phases are studied using both the liquid drop model as well as the Thomas-Fermi approximation. We compare the energy per nucleon for each geometry (spherical nuclei, cylindrical nuclei, nuclear slabs, cylindrical holes, and spherical holes) to obtain the ground state phase as a function of density. We find that the size of the Wigner-Seitz cell depends strongly on the model parameters, especially the coefficients of the density gradient interaction terms. We employ also the thermodynamic instability method to check the validity of the numerical solutions based on energy comparisons.

Analog geometry in an expanding fluid from AdS/CFT perspective

NASA Astrophysics Data System (ADS)

Bilić, Neven; Domazet, Silvije; Tolić, Dijana

2015-04-01

The dynamics of an expanding hadron fluid at temperatures below the chiral transition is studied in the framework of AdS/CFT correspondence. We establish a correspondence between the asymptotic AdS geometry in the 4 + 1 dimensional bulk with the analog spacetime geometry on its 3 + 1 dimensional boundary with the background fluid undergoing a spherical Bjorken type expansion. The analog metric tensor on the boundary depends locally on the soft pion dispersion relation and the four-velocity of the fluid. The AdS/CFT correspondence provides a relation between the pion velocity and the critical temperature of the chiral phase transition.

Stability of warped AdS3 vacua of topologically massive gravity

NASA Astrophysics Data System (ADS)

Anninos, Dionysios; Esole, Mboyo; Guica, Monica

2009-10-01

AdS3 vacua of topologically massive gravity (TMG) have been shown to be perturbatively unstable for all values of the coupling constant except the chiral point μl = 1. We study the possibility that the warped vacua of TMG, which exist for all values of μ, are stable under linearized perturbations. In this paper, we show that spacelike warped AdS3 vacua with Compère-Detournay boundary conditions are indeed stable in the range μl>3. This is precisely the range in which black hole solutions arise as discrete identifications of the warped AdS3 vacuum. The situation somewhat resembles chiral gravity: although negative energy modes do exist, they are all excluded by the boundary conditions, and the perturbative spectrum solely consists of boundary (pure large gauge) gravitons.

Quantification of Magnetic Surface and Edge States in an FeGe Nanostripe by Off-Axis Electron Holography

NASA Astrophysics Data System (ADS)

Song, Dongsheng; Li, Zi-An; Caron, Jan; Kovács, András; Tian, Huanfang; Jin, Chiming; Du, Haifeng; Tian, Mingliang; Li, Jianqi; Zhu, Jing; Dunin-Borkowski, Rafal E.

2018-04-01

Whereas theoretical investigations have revealed the significant influence of magnetic surface and edge states on Skyrmonic spin texture in chiral magnets, experimental studies of such chiral states remain elusive. Here, we study chiral edge states in an FeGe nanostripe experimentally using off-axis electron holography. Our results reveal the magnetic-field-driven formation of chiral edge states and their penetration lengths at 95 and 240 K. We determine values of saturation magnetization MS by analyzing the projected in-plane magnetization distributions of helices and Skyrmions. Values of MS inferred for Skyrmions are lower by a few percent than those for helices. We attribute this difference to the presence of chiral surface states, which are predicted theoretically in a three-dimensional Skyrmion model. Our experiments provide direct quantitative measurements of magnetic chiral boundary states and highlight the applicability of state-of-the-art electron holography for the study of complex spin textures in nanostructures.

The logarithmic Cardy case: Boundary states and annuli

NASA Astrophysics Data System (ADS)

Fuchs, Jürgen; Gannon, Terry; Schaumann, Gregor; Schweigert, Christoph

2018-05-01

We present a model-independent study of boundary states in the Cardy case that covers all conformal field theories for which the representation category of the chiral algebra is a - not necessarily semisimple - modular tensor category. This class, which we call finite CFTs, includes all rational theories, but goes much beyond these, and in particular comprises many logarithmic conformal field theories. We show that the following two postulates for a Cardy case are compatible beyond rational CFT and lead to a universal description of boundary states that realizes a standard mathematical setup: First, for bulk fields, the pairing of left and right movers is given by (a coend involving) charge conjugation; and second, the boundary conditions are given by the objects of the category of chiral data. For rational theories our proposal reproduces the familiar result for the boundary states of the Cardy case. Further, with the help of sewing we compute annulus amplitudes. Our results show in particular that these possess an interpretation as partition functions, a constraint that for generic finite CFTs is much more restrictive than for rational ones.

Chiral HPLC for a study of the optical purity of new liquid crystalline materials derived from lactic acid

NASA Astrophysics Data System (ADS)

Vojtylová, T.; Kašpar, M.; Hamplová, V.; Novotná, V.; Sýkora, D.

2014-08-01

New liquid crystalline (LC) materials were prepared by derivatization of lactic acid. First compound possesses the lactic acid unit as the only chiral center and the second group of LC materials contains two chiral centers. Mesomorphic properties of both the newly synthesized LC materials were studied and the presence of the SmA*-SmC* or exhibit the twist grain boundary (TGB) phases, namely TGBA and TGBC, in a wide range of temperatures down to the room temperature was established. The potential of high-performance liquid chromatography (HPLC) applying chiral stationary phases to separate enantiomers or diastereoisomers of the synthesized LC compounds was evaluated. Two different brands of commercial chiral sorbents, Lux Amylose-2 and Chiralpak AD-3, both based on modified silica with derivatized polysaccharide, were employed in the development of separation procedures. The optimized chiral HPLC method provided a baseline separation of the individual enantiomers for the LC material containing one chiral center. In the case of the more complex compound with two asymmetric carbon atoms, where four isomers exist, partial separation was reached only using the current chiral HPLC.

Nonlinear magnetic responses at the phase boundaries around helimagnetic and skyrmion lattice phases in MnSi: Evaluation of robustness of noncollinear spin texture

NASA Astrophysics Data System (ADS)

Tsuruta, K.; Mito, M.; Deguchi, H.; Kishine, J.; Kousaka, Y.; Akimitsu, J.; Inoue, K.

2018-03-01

The phase diagram of a cubic chiral magnet MnSi with multiple Dzyaloshinskii-Moriya (DM) vectors as a function of temperature T and dc magnetic field Hdc was investigated using intensity mapping of the odd-harmonic responses of ac magnetization (M1 ω and M3 ω), and the responses at phase boundaries were evaluated according to a prescription [J. Phys. Soc. Jpn. 84, 104707 (2015), 10.7566/JPSJ.84.104707]. By evaluating M3 ω/M1 ω appearing at phase boundaries, the robustness of noncollinear spin texture in both the helimagnetic (HM) and the skyrmion lattice (SkL) phases of MnSi was discussed. The robustness of vortices-type solitonic texture SkL in MnSi is smaller than those of both the single DM HM and chiral soliton lattice phases of a monoaxial chiral magnet Cr1 /3NbS2 , and furthermore the robustness of the multiple DM HM phase in MnSi is smaller than that of its SkL. Through magnetic diagnostics over the wide T -Hdc range, we found a new paramagnetic (PM) region with ac magnetic hysteresis, where spin fluctuations have been observed via electrical magnetochiral effect. The anomalies observed in the previous ultrasonic attenuation measurement correspond to the peak positions of out-of-phase M1 ω. The appearance of a new PM region occurs at a characteristic magnetic field, above which indeed the SkL phase appears. It has us suppose that the new PM region could be a phase with spin fluctuation like the skyrmion gas phase.

Graphene chiral liquid crystals and macroscopic assembled fibres

PubMed Central

Xu, Zhen; Gao, Chao

2011-01-01

Chirality and liquid crystals are both widely expressed in nature and biology. Helical assembly of mesophasic molecules and colloids may produce intriguing chiral liquid crystals. To date, chiral liquid crystals of 2D colloids have not been explored. As a typical 2D colloid, graphene is now receiving unprecedented attention. However, making macroscopic graphene fibres is hindered by the poor dispersibility of graphene and by the lack of an assembly method. Here we report that soluble, chemically oxidized graphene or graphene oxide sheets can form chiral liquid crystals in a twist-grain-boundary phase-like model with simultaneous lamellar ordering and long-range helical frustrations. Aqueous graphene oxide liquid crystals were continuously spun into metres of macroscopic graphene oxide fibres; subsequent chemical reduction gave the first macroscopic neat graphene fibres with high conductivity and good mechanical performance. The flexible, strong graphene fibres were knitted into designed patterns and into directionally conductive textiles. PMID:22146390

Topological dynamics of gyroscopic and Floquet lattices from Newton's laws

NASA Astrophysics Data System (ADS)

Lee, Ching Hua; Li, Guangjie; Jin, Guliuxin; Liu, Yuhan; Zhang, Xiao

2018-02-01

Despite intense interest in realizing topological phases across a variety of electronic, photonic, and mechanical platforms, the detailed microscopic origin of topological behavior often remains elusive. To bridge this conceptual gap, we show how hallmarks of topological modes—boundary localization and chirality—emerge from Newton's laws in mechanical topological systems. We first construct a gyroscopic lattice with analytically solvable edge modes, and show how the Lorentz and spring restoring forces conspire to support very robust "dangling bond" boundary modes. The chirality and locality of these modes intuitively emerges from microscopic balancing of restoring forces and cyclotron tendencies. Next, we introduce the highlight of this work, an experimentally realistic mechanical nonequilibrium (Floquet) Chern lattice driven by ac electromagnets. Through appropriate synchronization of the ac driving protocol, the Floquet lattice is "pushed around" by a rotating potential analogous to an object washed ashore by water waves. Besides hosting "dangling bond" chiral modes analogous to the gyroscopic boundary modes, our Floquet Chern lattice also supports peculiar half-period chiral modes with no static analog, i.e., analogs of anomalous Floquet Chern insulators edge modes. With key parameters controlled electronically, our setup has the advantage of being dynamically tunable for applications involving arbitrary Floquet modulations. The physical intuition gleaned from our two prototypical topological systems is applicable not just to arbitrarily complicated mechanical systems, but also photonic and electrical topological setups.

Radical chiral Floquet phases in a periodically driven Kitaev model and beyond

NASA Astrophysics Data System (ADS)

Po, Hoi Chun; Fidkowski, Lukasz; Vishwanath, Ashvin; Potter, Andrew C.

2017-12-01

We theoretically discover a family of nonequilibrium fractional topological phases in which time-periodic driving of a 2D system produces excitations with fractional statistics, and produces chiral quantum channels that propagate a quantized fractional number of qubits along the sample edge during each driving period. These phases share some common features with fractional quantum Hall states, but are sharply distinct dynamical phenomena. Unlike the integer-valued invariant characterizing the equilibrium quantum Hall conductance, these phases are characterized by a dynamical topological invariant that is a square root of a rational number, inspiring the label: radical chiral Floquet phases. We construct solvable models of driven and interacting spin systems with these properties, and identify an unusual bulk-boundary correspondence between the chiral edge dynamics and bulk "anyon time-crystal" order characterized by dynamical transmutation of electric-charge into magnetic-flux excitations in the bulk.

Chiral behavior of K →π l ν decay form factors in lattice QCD with exact chiral symmetry

NASA Astrophysics Data System (ADS)

Aoki, S.; Cossu, G.; Feng, X.; Fukaya, H.; Hashimoto, S.; Kaneko, T.; Noaki, J.; Onogi, T.; Jlqcd Collaboration

2017-08-01

We calculate the form factors of the K →π l ν semileptonic decays in three-flavor lattice QCD and study their chiral behavior as a function of the momentum transfer and the Nambu-Goldstone boson masses. Chiral symmetry is exactly preserved by using the overlap quark action, which enables us to directly compare the lattice data with chiral perturbation theory (ChPT). We generate gauge ensembles at a lattice spacing of 0.11 fm with four pion masses covering 290-540 MeV and a strange quark mass ms close to its physical value. By using the all-to-all quark propagator, we calculate the vector and scalar form factors with high precision. Their dependence on ms and the momentum transfer is studied by using the reweighting technique and the twisted boundary conditions for the quark fields. We compare the results for the semileptonic form factors with ChPT at next-to-next-to-leading order in detail. While many low-energy constants appear at this order, we make use of our data of the light meson electromagnetic form factors in order to control the chiral extrapolation. We determine the normalization of the form factors as f+(0 )=0.9636 (36 )(-35+57) and observe reasonable agreement of their shape with experiment.

Adding gauge fields to Kaplan's fermions

NASA Astrophysics Data System (ADS)

Blum, T.; Kärkkäinen, Leo

1994-04-01

We experiment with adding dynamical gauge field to Kaplan (defect) fermions. In the case of U (1) gauge theory we use an inhomogenous Higgs mechanism to restrict the 3d gauge dynamics to a planar 2d defect. In our simulations the 3d theory produce the correct 2d gauge dynamics. We measure fermion propagators with dynamical gauge fields. They posses the correct chiral structure. The fermions at the boundary of the support of the gauge field (waveguide) are non-chiral, and have a mass two times heavier than the chiral modes. Moreover, these modes cannot be excited by a source at the defect; implying that they are dynamically decoupled. We have also checked that the anomaly relation is fullfilled for the case of a smooth external gauge field.

Alternative auxiliary fields for chiral multiplets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nishino, Hitoshi; Rajpoot, Subhash

We study 3-form auxiliary field formulation for chiral multiplets in the Wess-Zumino model. The conventional auxiliary fields F and G are replaced by their Hodge duals K{sub {mu}}{sub {nu}}{sub {rho}}{sub {sigma}} and H{sub {mu}}{sub {nu}}{sub {rho}}{sub {sigma}} which are the field strengths of the 3-form potential auxiliary fields G{sub {mu}}{sub {nu}}{sub {rho}} and F{sub {mu}}{sub {nu}}{sub {rho}}. Even though duality transformations connect these two formulations, there exist certain differences from the conventional formulation. When boundary conditions are taken into account, the field equations in the 3-form formulation are equivalent to the conventional ones, while our Lagrangian is not. We alsomore » show that the new field strengths acquire generalized Chern-Simons terms. The O'Raifeartaigh mechanism works for spontaneous supersymmetry breaking also in the 3-form auxiliary field formulation via the boundary conditions on the 3-form auxiliary fields.« less

Chiral Magnetic Effect in Condensed Matters

NASA Astrophysics Data System (ADS)

Li, Qiang

The chiral magnetic effect is the generation of electrical current induced by chirality imbalance in the presence of magnetic field. It is a macroscopic manifestation of the quantum chiral anomaly in systems possessing charged chiral fermions. In quark-gluon plasma containing nearly massless quarks, the chirality imbalance is sourced by the topological transitions. In condensed matter systems, the chiral quasiparticles emerge in the 3D Dirac and Weyl semimetals having a linear dispersion relation. Recently, the chiral magnetic effect was discovered in a 3D Dirac semimetal - zirconium pentatelluride, ZrTe5, in which a large negative magnetoresistance is observed when magnetic field is parallel with the current. It is now reported in more than a dozen Dirac and Weyl semimetals. Broadly speaking, the chiral magnetic effect can exist in a variety of condensed matters. In some cases, a material may be transformed into a Weyl semimetal by magnetic field, exhibiting the chiral magnetic effect. In other cases, the chiral magnetic current may be generated in magnetic Dirac semimetals without external magnetic field, or in asymmetric Weyl semimetals without electric field where only a magnetic field and the source of chiral quasipartiles would be necessary. In the limit of conserved quasiparticle chirality, charge transport by the chiral magnetic current is non-dissipative. The powerful notion of chirality, originally discovered in high-energy and nuclear physics, holds promise in new ways of transmitting and processing information and energy. At the same time, chiral materials have opened a fascinating possibility to study the quantum dynamics of relativistic field theory in condensed matter experiments.

Topological Switching and Orbiting Dynamics of Colloidal Spheres Dressed with Chiral Nematic Solitons

PubMed Central

Porenta, T.; Čopar, S.; Ackerman, P. J.; Pandey, M. B.; Varney, M. C. M.; Smalyukh, I. I.; Žumer, S.

2014-01-01

Metastable configurations formed by defects, inclusions, elastic deformations and topological solitons in liquid crystals are a promising choice for building photonic crystals and metamaterials with a potential for new optical applications. Local optical modification of the director or introduction of colloidal inclusions into a moderately chiral nematic liquid crystal confined to a homeotropic cell creates localized multistable chiral solitons. Here we induce solitons that “dress” the dispersed spherical particles treated for tangential degenerate boundary conditions, and perform controlled switching of their state using focused optical beams. Two optically switchable distinct metastable states, toron and hopfion, bound to colloidal spheres into structures with different topological charges are investigated. Their structures are examined using Q-tensor based numerical simulations and compared to the profiles reconstructed from the experiments. A topological explanation of observed multistability is constructed. PMID:25477195

Topological switching and orbiting dynamics of colloidal spheres dressed with chiral nematic solitons.

PubMed

Porenta, T; Copar, S; Ackerman, P J; Pandey, M B; Varney, M C M; Smalyukh, I I; Žumer, S

2014-12-05

Metastable configurations formed by defects, inclusions, elastic deformations and topological solitons in liquid crystals are a promising choice for building photonic crystals and metamaterials with a potential for new optical applications. Local optical modification of the director or introduction of colloidal inclusions into a moderately chiral nematic liquid crystal confined to a homeotropic cell creates localized multistable chiral solitons. Here we induce solitons that "dress" the dispersed spherical particles treated for tangential degenerate boundary conditions, and perform controlled switching of their state using focused optical beams. Two optically switchable distinct metastable states, toron and hopfion, bound to colloidal spheres into structures with different topological charges are investigated. Their structures are examined using Q-tensor based numerical simulations and compared to the profiles reconstructed from the experiments. A topological explanation of observed multistability is constructed.

Flatspace chiral supergravity

NASA Astrophysics Data System (ADS)

Bagchi, Arjun; Basu, Rudranil; Detournary, Stéphane; Parekh, Pulastya

2018-05-01

We propose a holographic duality between a 2 dimensional (2d) chiral superconformal field theory and a certain theory of supergravity in 3d with flatspace boundary conditions that is obtained as a double scaling limit of a parity breaking theory of supergravity. We show how the asymptotic symmetries of the bulk theory reduce from the "despotic" super Bondi-Metzner-Sachs algebra (or equivalently the inhomogeneous super Galilean conformal algebra) to a single copy of the super-Virasoro algebra in this limit and also reproduce the same reduction from a study of null vectors in the putative 2d dual field theory.

Chiral magnetic effect without chirality source in asymmetric Weyl semimetals

NASA Astrophysics Data System (ADS)

Kharzeev, Dmitri E.; Kikuchi, Yuta; Meyer, René

2018-05-01

We describe a new type of the chiral magnetic effect (CME) that should occur in Weyl semimetals (WSMs) with an asymmetry in the dispersion relations of the left- and right-handed (LH and RH) chiral Weyl fermions. In such materials, time-dependent pumping of electrons from a non-chiral external source can generate a non-vanishing chiral chemical potential. This is due to the different capacities of the LH and RH chiral Weyl cones arising from the difference in the density of states in the LH and RH cones. The chiral chemical potential then generates, via the chiral anomaly, a current along the direction of an applied magnetic field even in the absence of an external electric field. The source of chirality imbalance in this new setup is thus due to the band structure of the system and the presence of (non-chiral) electron source, and not due to the parallel electric and magnetic fields. We illustrate the effect by an argument based on the effective field theory, and by the chiral kinetic theory calculation for a rotationally invariant WSM with different Fermi velocities in the left and right chiral Weyl cones; we also consider the case of a WSM with Weyl nodes at different energies. We argue that this effect is generically present in WSMs with different dispersion relations for LH and RH chiral Weyl cones, such as SrSi2 recently predicted as a WSM with broken inversion and mirror symmetries, as long as the chiral relaxation time is much longer than the transport scattering time.

Probing Chirality in Superfluid 3He-A: Free surface as an ideal boundary condition

NASA Astrophysics Data System (ADS)

Kono, Kimitoshi

2013-03-01

Superfluid 3He is known as a typical topological superfluid. A recent theoretical investigation suggests Majorana surface states at the free surface of superfluid 3He-B phase. On the other hand, superfluid 3He-A is known as a chiral superfluid. The scattering of quasiparticle from small object is predicted to be skew with respect to an anisotropy axis. We have developed an experimental technique to study transport properties of ions under the free surface of superfluid 3He. By using this technique, we can investigate interaction between elementary excitations in superfluid 3He and small objects under well-controlled conditions. For example, in 3He-B interaction with Majorana surface states, although no interaction is expected, will be investigated, whereas in 3He-A skew scattering of quasiparticle from electron bubbles will be probed. In this paper, we present the recent results of transport properties of electron bubbles trapped below the free surface of superfluid 3He. In particular, experimental evidences of the skew scattering and chirality of superfluid 3He-A will be presented. The skew scattering of quasiparticle in 3He-A from electron bubble results in a bubble transport analogous to the Hall effect, where the anisotropy vector of 3He-A behaves as if it was a magnetic field in the Hall effect. Under experimental conditions, the effect is observed as an analogue of edge magnetoplasmon effect. After the analysis of data, we obtained a reasonable qualitative agreement with the theory. This work is done in collaboration with Hiroki Ikegami.

Laminar and Turbulent Dynamos in Chiral Magnetohydrodynamics. I. Theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rogachevskii, Igor; Kleeorin, Nathan; Ruchayskiy, Oleg

2017-09-10

The magnetohydrodynamic (MHD) description of plasmas with relativistic particles necessarily includes an additional new field, the chiral chemical potential associated with the axial charge (i.e., the number difference between right- and left-handed relativistic fermions). This chiral chemical potential gives rise to a contribution to the electric current density of the plasma ( chiral magnetic effect ). We present a self-consistent treatment of the chiral MHD equations , which include the back-reaction of the magnetic field on a chiral chemical potential and its interaction with the plasma velocity field. A number of novel phenomena are exhibited. First, we show that themore » chiral magnetic effect decreases the frequency of the Alfvén wave for incompressible flows, increases the frequencies of the Alfvén wave and of the fast magnetosonic wave for compressible flows, and decreases the frequency of the slow magnetosonic wave. Second, we show that, in addition to the well-known laminar chiral dynamo effect, which is not related to fluid motions, there is a dynamo caused by the joint action of velocity shear and chiral magnetic effect. In the presence of turbulence with vanishing mean kinetic helicity, the derived mean-field chiral MHD equations describe turbulent large-scale dynamos caused by the chiral alpha effect, which is dominant for large fluid and magnetic Reynolds numbers. The chiral alpha effect is due to an interaction of the chiral magnetic effect and fluctuations of the small-scale current produced by tangling magnetic fluctuations (which are generated by tangling of the large-scale magnetic field by sheared velocity fluctuations). These dynamo effects may have interesting consequences in the dynamics of the early universe, neutron stars, and the quark–gluon plasma.« less

Involution Requirement on a Boundary Makes Massless Fermions Compactified on a Finite Flat Disk Mass Protected

NASA Astrophysics Data System (ADS)

Mankoč Borštnik, N. S.; Nielsen, H. B.

2006-12-01

The genuine Kaluza-Klein-like theories--with no fields in addition to gravity--have difficulties with the existence of massless spinors after the compactification of some space dimensions \\cite{witten}. We proposed (Phys. Lett. B 633 (2006)771) such a boundary condition for spinors in 1+5 compactified on a flat disk that ensures masslessness of spinors in d=1+3 as well as their chiral coupling to the corresponding background gauge field (which solves equations of motion for a free field linear in the Riemann curvature). In this paper we study the same toy model: M^{(1+3)} x M^{(2)}, looking this time for an involution which transforms a space of solutions of Weyl equations in d=1+5 from the outside of the flat disk in x^5 and x^6 into its inside, allowing massless spinor of only one handedness--and accordingly assures mass protection--and of one charge--1/2--and infinitely many massive spinors of the same charge, chirally coupled to the corresponding background gauge field. We reformulate the operator of momentum so that it is Hermitean on the vector space of spinor states obeying the involution boundary condition.

Chirality Differentiation by Diffusion in Chiral Nematic Liquid Crystals

NASA Astrophysics Data System (ADS)

Jiang, Jinghua; Yang, Deng-Ke

2017-01-01

Chirality is of great importance in the living world. It helps differentiate biochemical reactions such as those that take place during digestion. It may also help differentiate physical processes such as diffusion. Aiming to study the latter effect, we investigate the diffusion of guest chiral molecules in chiral nematic (cholesteric) liquid-crystal hosts. We discover that the diffusion dramatically depends on the handedness of the guest and host molecules and the chiral differentiation is greatly enhanced by the proper alignment of the liquid-crystal host. The diffusion of a guest chiral molecule in a chiral host with the same handedness is much faster than in a chiral host with opposite handedness. We also observe that the differentiation of chirality depends on the diffusion direction with respect to the twisting direction (helical axis). These results might be important in understanding effects of chirality on physical processes that take place in biological organisms. In addition, this effect could be utilized for enantiomer separation.

Magnetic antiskyrmions above room temperature in tetragonal Heusler materials

NASA Astrophysics Data System (ADS)

Nayak, Ajaya K.; Kumar, Vivek; Ma, Tianping; Werner, Peter; Pippel, Eckhard; Sahoo, Roshnee; Damay, Franoise; Rößler, Ulrich K.; Felser, Claudia; Parkin, Stuart S. P.

2017-08-01

Magnetic skyrmions are topologically stable, vortex-like objects surrounded by chiral boundaries that separate a region of reversed magnetization from the surrounding magnetized material. They are closely related to nanoscopic chiral magnetic domain walls, which could be used as memory and logic elements for conventional and neuromorphic computing applications that go beyond Moore’s law. Of particular interest is ‘racetrack memory’, which is composed of vertical magnetic nanowires, each accommodating of the order of 100 domain walls, and that shows promise as a solid state, non-volatile memory with exceptional capacity and performance. Its performance is derived from the very high speeds (up to one kilometre per second) at which chiral domain walls can be moved with nanosecond current pulses in synthetic antiferromagnet racetracks. Because skyrmions are essentially composed of a pair of chiral domain walls closed in on themselves, but are, in principle, more stable to perturbations than the component domain walls themselves, they are attractive for use in spintronic applications, notably racetrack memory. Stabilization of skyrmions has generally been achieved in systems with broken inversion symmetry, in which the asymmetric Dzyaloshinskii-Moriya interaction modifies the uniform magnetic state to a swirling state. Depending on the crystal symmetry, two distinct types of skyrmions have been observed experimentally, namely, Bloch and Néel skyrmions. Here we present the experimental manifestation of another type of skyrmion—the magnetic antiskyrmion—in acentric tetragonal Heusler compounds with D2d crystal symmetry. Antiskyrmions are characterized by boundary walls that have alternating Bloch and Néel type as one traces around the boundary. A spiral magnetic ground-state, which propagates in the tetragonal basal plane, is transformed into an antiskyrmion lattice state under magnetic fields applied along the tetragonal axis over a wide range of temperatures. Direct imaging by Lorentz transmission electron microscopy shows field-stabilized antiskyrmion lattices and isolated antiskyrmions from 100 kelvin to well beyond room temperature, and zero-field metastable antiskyrmions at low temperatures. These results enlarge the family of magnetic skyrmions and pave the way to the engineering of complex bespoke designed skyrmionic structures.

DC conductivity of twisted bilayer graphene: Angle-dependent transport properties and effects of disorder

NASA Astrophysics Data System (ADS)

Andelković, M.; Covaci, L.; Peeters, F. M.

2018-03-01

The in-plane dc conductivity of twisted bilayer graphene is calculated using an expansion of the real-space Kubo-Bastin conductivity in terms of Chebyshev polynomials. We investigate within a tight-binding approach the transport properties as a function of rotation angle, applied perpendicular electric field, and vacancy disorder. We find that for high-angle twists, the two layers are effectively decoupled, and the minimum conductivity at the Dirac point corresponds to double the value observed in monolayer graphene. This remains valid even in the presence of vacancies, hinting that chiral symmetry is still preserved. On the contrary, for low twist angles, the conductivity at the Dirac point depends on the twist angle and is not protected in the presence of disorder. Furthermore, for low angles and in the presence of an applied electric field, we find that the chiral boundary states emerging between AB and BA regions contribute to the dc conductivity, despite the appearance of localized states in the AA regions. The results agree qualitatively with recent transport experiments in low-angle twisted bilayer graphene.

Unitarity problems in 3D gravity theories

NASA Astrophysics Data System (ADS)

Alkac, Gokhan; Basanisi, Luca; Kilicarslan, Ercan; Tekin, Bayram

2017-07-01

We revisit the problem of the bulk-boundary unitarity clash in 2 +1 -dimensional gravity theories, which has been an obstacle in providing a viable dual two-dimensional conformal field theory for bulk gravity in anti-de Sitter (AdS) spacetime. Chiral gravity, which is a particular limit of cosmological topologically massive gravity (TMG), suffers from perturbative log-modes with negative energies inducing a nonunitary logarithmic boundary field theory. We show here that any f (R ) extension of TMG does not improve the situation. We also study the perturbative modes in the metric formulation of minimal massive gravity—originally constructed in a first-order formulation—and find that the massive mode has again negative energy except in the chiral limit. We comment on this issue and also discuss a possible solution to the problem of negative-energy modes. In any of these theories, the infinitesimal dangerous deformations might not be integrable to full solutions; this suggests a linearization instability of AdS spacetime in the direction of the perturbative log-modes.

Chiral magnetic effect in lattice QCD with a chiral chemical potential.

PubMed

Yamamoto, Arata

2011-07-15

We perform a first lattice QCD simulation including a two-flavor dynamical fermion with a chiral chemical potential. Because the chiral chemical potential gives rise to no sign problem, we can exactly analyze a chirally imbalanced QCD matter by Monte Carlo simulation. By applying an external magnetic field to this system, we obtain a finite induced current along the magnetic field, which corresponds to the chiral magnetic effect. The obtained induced current is proportional to the magnetic field and to the chiral chemical potential, which is consistent with an analytical prediction.

Chiral magnetic effect of light

NASA Astrophysics Data System (ADS)

Hayata, Tomoya

2018-05-01

We study a photonic analog of the chiral magnetic (vortical) effect. We discuss that the vector component of magnetoelectric tensors plays a role of "vector potential," and its rotation is understood as "magnetic field" of a light. Using the geometrical optics approximation, we show that "magnetic fields" cause an anomalous shift of a wave packet of a light through an interplay with the Berry curvature of photons. The mechanism is the same as that of the chiral magnetic (vortical) effect of a chiral fermion, so that we term the anomalous shift "chiral magnetic effect of a light." We further study the chiral magnetic effect of a light beyond geometric optics by directly solving the transmission problem of a wave packet at a surface of a magnetoelectric material. We show that the experimental signal of the chiral magnetic effect of a light is the nonvanishing of transverse displacements for the beam normally incident to a magnetoelectric material.

Chiral magnetic effect in condensed matter systems

DOE PAGES

Li, Qiang; Kharzeev, Dmitri E.

2016-12-01

The chiral magnetic effect is the generation of electrical current induced by chirality imbalance in the presence of magnetic field. It is a macroscopic manifestation of the quantum anomaly in relativistic field theory of chiral fermions. In the quark-gluon plasma, the axial anomaly induces topological charge changing transition that results in the generation of electrical current along the magnetic field. In condensed matter systems, the chiral magnetic effect was first predicted in the gapless semiconductors with tow energy bands having pointlike degeneracies. In addition, thirty years later after this prediction, the chiral magnetic effect was finally observed in the 3Dmore » Dirac/Weyl semimetals.« less

New excitations in the Thirring model

NASA Astrophysics Data System (ADS)

Cortés, J. L.; Gamboa, J.; Schmidt, I.; Zanelli, J.

1998-12-01

The quantization of the massless Thirring model in the light-cone using functional methods is considered. The need to compactify the coordinate x- in the light-cone spacetime implies that the quantum effective action for left-handed fermions contains excitations similar to abelian instantons produced by composite of left-handed fermions. Right-handed fermions don't have a similar effective action. Thus, quantum mechanically, chiral symmetry must be broken as a result of the topological excitations. The conserved charge associated to the topological states is quantized. Different cases with only fermionic excitations or bosonic excitations or both can occur depending on the boundary conditions and the value of the coupling.

Charge/spin supercurrent and the Fulde-Ferrell state induced by crystal deformation in Weyl/Dirac superconductors

NASA Astrophysics Data System (ADS)

Matsushita, Taiki; Liu, Tianyu; Mizushima, Takeshi; Fujimoto, Satoshi

2018-04-01

It has been predicted that emergent chiral magnetic fields can be generated by crystal deformation in Weyl/Dirac metals and superconductors. The emergent fields give rise to chiral anomaly phenomena as in the case of Weyl semimetals with usual electromagnetic fields. Here, we clarify effects of the chiral magnetic field on Cooper pairs in Weyl/Dirac superconductors on the basis of the Ginzburg-Landau equation microscopically derived from the quasiclassical Eilenberger formalism. It is found that Cooper pairs are affected by the emergent chiral magnetic field in a dramatic way, and the pseudo-Lorentz force due to the chiral magnetic field stabilizes the Fulde-Ferrell state and causes a charge/spin supercurrent, which flows parallel to the chiral magnetic field in the case of Weyl/Dirac superconductors. This effect is in analogy with the chiral magnetic effect of Weyl semimetals. In addition, we elucidate that neither Meissner effect nor vortex state due to chiral magnetic fields occurs.

Photoexcitation circular dichroism in chiral molecules

NASA Astrophysics Data System (ADS)

Beaulieu, S.; Comby, A.; Descamps, D.; Fabre, B.; Garcia, G. A.; Géneaux, R.; Harvey, A. G.; Légaré, F.; Mašín, Z.; Nahon, L.; Ordonez, A. F.; Petit, S.; Pons, B.; Mairesse, Y.; Smirnova, O.; Blanchet, V.

2018-05-01

Chiral effects appear in a wide variety of natural phenomena and are of fundamental importance in science, from particle physics to metamaterials. The standard technique of chiral discrimination—photoabsorption circular dichroism—relies on the magnetic properties of a chiral medium and yields an extremely weak chiral response. Here, we propose and demonstrate an orders of magnitude more sensitive type of circular dichroism in neutral molecules: photoexcitation circular dichroism. This technique does not rely on weak magnetic effects, but takes advantage of the coherent helical motion of bound electrons excited by ultrashort circularly polarized light. It results in an ultrafast chiral response and the efficient excitation of a macroscopic chiral density in an initially isotropic ensemble of randomly oriented chiral molecules. We probe this excitation using linearly polarized laser pulses, without the aid of further chiral interactions. Our time-resolved study of vibronic chiral dynamics opens a way to the efficient initiation, control and monitoring of chiral chemical change in neutral molecules at the level of electrons.

Laminar and Turbulent Dynamos in Chiral Magnetohydrodynamics. II. Simulations

NASA Astrophysics Data System (ADS)

Schober, Jennifer; Rogachevskii, Igor; Brandenburg, Axel; Boyarsky, Alexey; Fröhlich, Jürg; Ruchayskiy, Oleg; Kleeorin, Nathan

2018-05-01

Using direct numerical simulations (DNS), we study laminar and turbulent dynamos in chiral magnetohydrodynamics with an extended set of equations that accounts for an additional contribution to the electric current due to the chiral magnetic effect (CME). This quantum phenomenon originates from an asymmetry between left- and right-handed relativistic fermions in the presence of a magnetic field and gives rise to a chiral dynamo. We show that the magnetic field evolution proceeds in three stages: (1) a small-scale chiral dynamo instability, (2) production of chiral magnetically driven turbulence and excitation of a large-scale dynamo instability due to a new chiral effect (α μ effect), and (3) saturation of magnetic helicity and magnetic field growth controlled by a conservation law for the total chirality. The α μ effect becomes dominant at large fluid and magnetic Reynolds numbers and is not related to kinetic helicity. The growth rate of the large-scale magnetic field and its characteristic scale measured in the numerical simulations agree well with theoretical predictions based on mean-field theory. The previously discussed two-stage chiral magnetic scenario did not include stage (2), during which the characteristic scale of magnetic field variations can increase by many orders of magnitude. Based on the findings from numerical simulations, the relevance of the CME and the chiral effects revealed in the relativistic plasma of the early universe and of proto-neutron stars are discussed.

Chiral Polymers.

DTIC Science & Technology

1984-10-01

regardless of the method of polymerization. The styrene-bead copolymers were packed in HPLC columns, but none were especiall, effective in separating...enantiomers in a racemic mixture. The chiral butyrolactone polymer was coated on silica, but this material did not effect resolution of racemic mixtures in an...been effected utilizing chiral oxazolines3 prompted the initial efforts to synthesize various chiral 2-vinyl- oxazoline monomers for incorporation

FATE AND EFFECTS OF THE ENANTIOMERS OF CHIRAL ENVIRONMENTAL POLLUTANTS

EPA Science Inventory

Enantiomers, the mirror image isomers of chiral compounds, are known to be selective in their interaction with other chiral molecules, including enzymes and other biochemicals. This holds true for pesticides, about 25% of which are chiral molecules, and other chiral environmental...

Spin-Selective Transmission and Devisable Chirality in Two-Layer Metasurfaces.

PubMed

Li, Zhancheng; Liu, Wenwei; Cheng, Hua; Chen, Shuqi; Tian, Jianguo

2017-08-15

Chirality is a nearly ubiquitous natural phenomenon. Its minute presence in most naturally occurring materials makes it incredibly difficult to detect. Recent advances in metasurfaces indicate that they exhibit devisable chirality in novel forms; this finding offers an effective opening for studying chirality and its features in such nanostructures. These metasurfaces display vast possibilities for highly sensitive chirality discrimination in biological and chemical systems. Here, we show that two-layer metasurfaces based on twisted nanorods can generate giant spin-selective transmission and support engineered chirality in the near-infrared region. Two designed metasurfaces with opposite spin-selective transmission are proposed for treatment as enantiomers and can be used widely for spin selection and enhanced chiral sensing. Specifically, we demonstrate that the chirality in these proposed metasurfaces can be adjusted effectively by simply changing the orientation angle between the twisted nanorods. Our results offer simple and straightforward rules for chirality engineering in metasurfaces and suggest intriguing possibilities for the applications of such metasurfaces in spin optics and chiral sensing.

Active chiral fluids.

PubMed

Fürthauer, S; Strempel, M; Grill, S W; Jülicher, F

2012-09-01

Active processes in biological systems often exhibit chiral asymmetries. Examples are the chirality of cytoskeletal filaments which interact with motor proteins, the chirality of the beat of cilia and flagella as well as the helical trajectories of many biological microswimmers. Here, we derive constitutive material equations for active fluids which account for the effects of active chiral processes. We identify active contributions to the antisymmetric part of the stress as well as active angular momentum fluxes. We discuss four types of elementary chiral motors and their effects on a surrounding fluid. We show that large-scale chiral flows can result from the collective behavior of such motors even in cases where isolated motors do not create a hydrodynamic far field.

Dispersion relations for electromagnetic wave propagation in chiral plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gao, M. X.; Guo, B., E-mail: binguo@whut.edu.cn; Peng, L.

2014-11-15

The dispersion relations for electromagnetic wave propagation in chiral plasmas are derived using a simplified method and investigated in detail. With the help of the dispersion relations for each eignwave, we explore how the chiral plasmas exhibit negative refraction and investigate the frequency region for negative refraction. The results show that chirality can induce negative refraction in plasmas. Moreover, both the degree of chirality and the external magnetic field have a significant effect on the critical frequency and the bandwidth of the frequency for negative refraction in chiral plasmas. The parameter dependence of the effects is calculated and discussed.

Resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1-phenylethylamine: chiral discrimination mechanism.

PubMed

Peng, Yangfeng; He, Quan; Rohani, Sohrab; Jenkins, Hilary

2012-05-01

During the resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1-phenylethylamine, the crystals of the less soluble salt were grown, and their structure were determined and presented. The chiral discrimination mechanism was investigated by examining the weak intermolecular interactions (such as hydrogen bond, CH/π, and van der Waals interactions) and molecular packing mode in crystal structure of the less soluble diastereomeric salt. A one-dimensional double-chain hydrogen-bonding network and a "lock-and-key" supramolecular packing mode are disclosed. The investigation demonstrates that hydrophobic layers with corrugated surfaces can fit into the grooves of one another to realize a compact packing, when the molecular structure of resolving agent is much larger than that of the racemate. This "lock-and-key" assembly is recognized to be another characteristic of molecular packing contributing to the chiral discrimination, in addition to the well-known sandwich-like packing by hydrophobic layers with planar boundary surfaces. Copyright © 2012 Wiley Periodicals, Inc.

Self-assembly and electrostriction of arrays and chains of hopfion particles in chiral liquid crystals

PubMed Central

Ackerman, Paul J.; van de Lagemaat, Jao; Smalyukh, Ivan I.

2015-01-01

Some of the most exotic condensed matter phases, such as twist grain boundary and blue phases in liquid crystals and Abrikosov phases in superconductors, contain arrays of topological defects in their ground state. Comprised of a triangular lattice of double-twist tubes of magnetization, the so-called ‘A-phase’ in chiral magnets is an example of a thermodynamically stable phase with topologically nontrivial solitonic field configurations referred to as two-dimensional skyrmions, or baby-skyrmions. Here we report that three-dimensional skyrmions in the form of double-twist tori called ‘hopfions’, or ‘torons’ when accompanied by additional self-compensating defects, self-assemble into periodic arrays and linear chains that exhibit electrostriction. In confined chiral nematic liquid crystals, this self-assembly is similar to that of liquid crystal colloids and originates from long-range elastic interactions between particle-like skyrmionic torus knots of molecular alignment field, which can be tuned from isotropic repulsive to weakly or highly anisotropic attractive by low-voltage electric fields. PMID:25607778

Enhanced Chiral Discriminatory van der Waals Interactions Mediated by Chiral Surfaces

NASA Astrophysics Data System (ADS)

Barcellona, Pablo; Safari, Hassan; Salam, A.; Buhmann, Stefan Yoshi

2017-05-01

We predict a discriminatory interaction between a chiral molecule and an achiral molecule which is mediated by a chiral body. To achieve this, we generalize the van der Waals interaction potential between two ground-state molecules with electric, magnetic, and chiral response to nontrivial environments. The force is evaluated using second-order perturbation theory with an effective Hamiltonian. Chiral media enhance or reduce the free interaction via many-body interactions, making it possible to measure the chiral contributions to the van der Waals force with current technology. The van der Waals interaction is discriminatory with respect to enantiomers of different handedness and could be used to separate enantiomers. We also suggest a specific geometric configuration where the electric contribution to the van der Waals interaction is zero, making the chiral component the dominant effect.

Effect of molecular structure of tartrates on chiral recognition of tartrate-boric acid complex chiral selectors in chiral microemulsion electrokinetic chromatography.

PubMed

Hu, Shao-Qiang; Chen, Yong-Lei; Zhu, Hua-Dong; Shi, Hai-Jun; Yan, Na; Chen, Xing-Guo

2010-08-20

Eight l-tartrates and a d-tartrate with different alcohol moieties were used as chiral oils to prepare chiral microemulsions, which were utilized in conjunction with borate buffer to separate the enantiomers of beta-blockers or structurally related compounds by the chiral microemulsion electrokinetic chromatography (MEEKC) method. Among them, six were found to have a relatively good chiral separation performance and their chiral recognition effect in terms of both enantioselectivity and resolution increases linearly with the number of carbon atoms in the alkyl group of alcohol moiety. The tartrates containing alkyl groups of different structures but the same number of carbon atoms, i.e. one of straight chain and one of branched chain, provide similar enantioseparations. The trend was elucidated according to the changes in the difference of the steric matching between the molecules of two enantiomers and chiral selector. Furthermore, it was demonstrated for the first time that a water insoluble solid compound, di-i-butyl l-tartrate (mp. 73.5 degrees C), can be used as an oil to prepare a stable microemulsion to be used in the chiral MEEKC successfully. And a critical effect of the microemulsion for chiral separation, which has never been reported before, was found in this experiment, namely providing a hydrophobic environment to strengthen the interactions between the chiral selector and enantiomers. Copyright 2010 Elsevier B.V. All rights reserved.

Enantioselective environmental toxicology of chiral pesticides.

PubMed

Ye, Jing; Zhao, Meirong; Niu, Lili; Liu, Weiping

2015-03-16

The enantioselective environmental toxic effect of chiral pesticides is becoming more important. As the industry develops, increasing numbers of chiral insecticides and herbicides will be introduced into use, potentially posing toxic effects on nontarget living beings. Chiral pesticides, including herbicides such as acylanilides, phenoxypropanoic acids, and imidazolinones, and insecticides such as synthetic pyrethroids, organophosphates, and DDT often behave enantioselectively during agricultural use. These compounds also pose unpredictable enantioselective ecological threats to nontarget living beings and/or humans, affecting the food chain and entire ecosystems. Thus, to investigate the enantioselective toxic effects of chiral insecticides and herbicides is necessary during environmental protection. The environmental toxicology of chiral pesticides, especially the findings obtained from studies conducted in our laboratory during the past 10 years, is reviewed.

Experimental Overview of the Search for Chiral Effects at RHIC

NASA Astrophysics Data System (ADS)

Wang, Gang

2017-01-01

In high-energy heavy-ion collisions, various novel transport phenomena in local chiral domains result from the interplay of quantum anomalies with magnetic field and vorticity, and could survive the expansion of the fireball and be detected in experiments. Among these phenomena are the chiral magnetic effect, the chiral vortical effect and the chiral magnetic wave, the experimental searches for which have aroused extensive interest. This review will describe the current status of experimental studies at Relativistic Heavy Ion Collider at BNL, and outline the future work in experiment needed to eliminate the existing uncertainties in the interpretation of the data.

Chiral filtration-induced spin/valley polarization in silicene line defects

NASA Astrophysics Data System (ADS)

Ren, Chongdan; Zhou, Benhu; Sun, Minglei; Wang, Sake; Li, Yunfang; Tian, Hongyu; Lu, Weitao

2018-06-01

The spin/valley polarization in silicene with extended line defects is investigated according to the chiral filtration mechanism. It is shown that the inner-built quantum Hall pseudo-edge states with identical chirality can serve as a chiral filter with a weak magnetic field and that the transmission process is restrained/strengthened for chiral states with reversed/identical chirality. With two parallel line defects, which act as natural chiral filtration, the filter effect is greatly enhanced, and 100% spin/valley polarization can be achieved.

Electric line source illumination of a chiral cylinder placed in another chiral background medium

NASA Astrophysics Data System (ADS)

Aslam, M.; Saleem, A.; Awan, Z. A.

2018-05-01

An electric line source illumination of a chiral cylinder embedded in a chiral background medium is considered. The field expressions inside and outside of a chiral cylinder have been derived using the wave field decomposition approach. The effects of various chiral cylinders, chiral background media and source locations upon the scattering gain pattern have been investigated. It is observed that the chiral background reduces the backward scattering gain as compared to the free space background for a dielectric cylinder. It is also studied that by moving a line source away from a cylinder reduces the backward scattering gain for a chiral cylinder placed in a chiral background under some specific conditions. A unique phenomenon of reduced scattering gain has been observed at a specific observation angle for a chiral cylinder placed in a chiral background having an electric line source location of unity free space wavelength. An isotropic scattering gain pattern is observed for a chiral nihility background provided that if cylinder is chiral or chiral nihility type. It is also observed that this isotropic behaviour is independent of background and cylinder chirality.

Simulating Chiral Magnetic and Separation Effects with Spin-Orbit Coupled Atomic Gases

PubMed Central

Huang, Xu-Guang

2016-01-01

The chiral magnetic and chiral separation effects—quantum-anomaly-induced electric current and chiral current along an external magnetic field in parity-odd quark-gluon plasma—have received intense studies in the community of heavy-ion collision physics. We show that analogous effects occur in rotating trapped Fermi gases with Weyl-Zeeman spin-orbit coupling where the rotation plays the role of an external magnetic field. These effects can induce a mass quadrupole in the atomic cloud along the rotation axis which may be tested in future experiments. Our results suggest that the spin-orbit coupled atomic gases are potential simulators of the chiral magnetic and separation effects. PMID:26868084

ENANTIOMER-SPECIFIC EFFECTS OF CHIRAL POLLUTANTS

EPA Science Inventory

Enantiomers, the mirror image isomers of chiral pollutants, are known to be selective in their interaction with other chiral molecules, including enzymes and other biochemicals. Considerable research has shown, for example, that chiral pesticides are degraded selectively by micr...

Chirality effect in disordered graphene ribbon junctions

NASA Astrophysics Data System (ADS)

Long, Wen

2012-05-01

We investigate the influence of edge chirality on the electronic transport in clean or disordered graphene ribbon junctions. By using the tight-binding model and the Landauer-Büttiker formalism, the junction conductance is obtained. In the clean sample, the zero-magnetic-field junction conductance is strongly chirality-dependent in both unipolar and bipolar ribbons, whereas the high-magnetic-field conductance is either chirality-independent in the unipolar or chirality-dependent in the bipolar ribbon. Furthermore, we study the disordered sample in the presence of magnetic field and find that the junction conductance is always chirality-insensitive for both unipolar and bipolar ribbons with adequate disorders. In addition, the disorder-induced conductance plateaus can exist in all chiral bipolar ribbons provided the disorder strength is moderate. These results suggest that we can neglect the effect of edge chirality in fabricating electronic devices based on the magnetotransport in a disordered graphene ribbon.

Synergistic Enhancement of Microwave Absorption Using Hybridized Polyaniline@helical CNTs with Dual Chirality.

PubMed

Tian, Xin; Meng, Fanbin; Meng, Fanchen; Chen, Xiangnan; Guo, Yifan; Wang, Ying; Zhu, Wenjun; Zhou, Zuowan

2017-05-10

In this study, we designed a dual-chirality hierarchical structure to achieve a synergistically enhanced effect in microwave absorption via the hybridization of nanomaterials. Herein, polyaniline (PANi) nanorods with tunable chirality are grown on helical carbon nanotubes (HCNTs), a typical nanoscale chiral structure, through in situ polymerization. The experimental results show that the hierarchical hybrids (PANi@HCNTs) exhibit distinctly dual chirality and a significant enhancement in electromagnetic (EM) losses compared to those of either pure PANi or HCNTs. The maximum reflection loss of the as-prepared hybrids can reach -32.5 dB at 8.9 GHz. Further analysis demonstrates that combinations of chiral acid-doped PANi and coiled HCNTs with molecular and nanoscale chirality lead to synergistic effects resulting from the dual chirality. The so-called cross-polarization may result in additional interactions with induced EM waves in addition to multiscaled relaxations from functional groups and interfacial polarizations, which can benefit EM absorption.

IR properties of chiral effects in pionic matter

NASA Astrophysics Data System (ADS)

Avdoshkin, A.; Sadofyev, A. V.; Zakharov, V. I.

2018-04-01

Chiral effects exhibit peculiar universality in idealized theoretical limits. However, they are known to be infrared sensitive and get modified in more realistic settings. In this work we study how the corresponding conductivities vary with the constituent mass. We concentrate on a pionic realization of chiral effects which provides a better control over infrared properties of the theory. The pionic medium is considered at finite vector and axial isospin chemical potentials in the presence of an external magnetic field. This system supports electric and axial isospin currents along the magnetic field which correspond to chiral magnetic and chiral separation effects. We show that these currents are sensitive to the finite mass of the constituents but the conductivities follow a simple scaling with the corresponding charge densities as one would expect for polarization effects. It is argued that this relation can capture the dependence of chiral effects on other infrared parameters. Finally, we briefly comment on the realization of the 't Hooft matching condition in pionic media at finite densities.

Effects of molecular chirality on self-assembly and switching in liquid crystals at the cross-over between rod-like and bent shapes.

PubMed

Ocak, Hale; Poppe, Marco; Bilgin-Eran, Belkız; Karanlık, Gürkan; Prehm, Marko; Tschierske, Carsten

2016-09-21

A bent-core compound derived from a 4-cyanoresorcinol core unit with two terephthalate based rod-like wings and carrying chiral 3,7-dimethyloctyloxy side chains has been synthesized in racemic and enantiomerically pure form and characterized by polarizing microscopy, differential scanning calorimetry, X-ray diffraction and electro-optical investigations to study the influence of molecular chirality on the superstructural chirality and polar order in lamellar liquid crystalline phases. Herein we demonstrate that the coupling of molecular chirality with superstructural layer chirality in SmCsPF domain phases (forming energetically distinct diastereomeric pairs) can fix the tilt direction and thus stabilize synpolar order, leading to bistable ferroelectric switching in the SmC* phases of the (S)-enantiomer, whereas tristable modes determine the switching of the racemate. Moreover, the mechanism of electric field induced molecular reorganization changes from a rotation around the molecular long axis in the racemate to a rotation on the tilt-cone for the (S)-enantiomer. At high temperature the enantiomer behaves like a rod-like molecule with a chirality induced ferroelectric SmC* phase and an electroclinic effect in the SmA'* phase. At reduced temperature sterically induced polarization, due to the bent molecular shape, becomes dominating, leading to much higher polarization values, thus providing access to high polarization ferroelectric materials with weakly bent compounds having only "weakly chiral" stereogenic units. Moreover, the field induced alignment of the SmCsPF(()*()) domains gives rise to a special kind of electroclinic effect appearing even in the absence of molecular chirality. Comparison with related compounds indicates that the strongest effects of chirality appear for weakly bent molecules with a relatively short coherence length of polar order, whereas for smectic phases with long range polar order the effects of the interlayer interfaces can override the chirality effects.

Phenomenology of anomalous chiral transports in heavy-ion collisions

NASA Astrophysics Data System (ADS)

Huang, Xu-Guang

2018-01-01

High-energy Heavy-ion collisions can generate extremely hot quark-gluon matter and also extremely strong magnetic fields and fluid vorticity. Once coupled to chiral anomaly, the magnetic fields and fluid vorticity can induce a variety of novel transport phenomena, including the chiral magnetic effect, chiral vortical effect, etc. Some of them require the environmental violation of parity and thus provide a means to test the possible parity violation in hot strongly interacting matter. We will discuss the underlying mechanism and implications of these anomalous chiral transports in heavy-ion collisions.

Rediscovering Chirality - Role of S-Metoprolol in Cardiovascular Disease Management.

PubMed

Mohan, Jagdish C; Shah, Siddharth N; Chinchansurkar, Sunny; Dey, Arindam; Jain, Rishi

2017-06-01

The process of drug discovery and development today encompass a myriad of paths for bringing a new therapeutic molecule that has minimal adverse effects and of optimal use to the patient. Chirality was proposed in the direction of providing a purer and safer form of drug [Ex- cetrizine and levocetrizine]. Decades have passed since the introduction of this concept and numerous chiral molecules are in existence in therapeutics, yet somehow this concept has been ignored. This review aims to rediscover the ignored facts about chirality, its benefits and clear some common myths considering the example of S-Metoprolol in the management of Hypertension and other cardiovascular diseases. Relevant articles from Pubmed, Embase, Medline and Google Scholar were searched using the terms "Chiral", "Chirality", "Enantiomers", "Isomers", "Isomerism", "Stereo-chemistry", and "S-Metoprolol". Out of 103 articles found 17 articles mentioning in general about the concept of chirality and articles on study of S-metoprolol in various cardiovascular diseases were then reviewed. Many articles mention about the importance of chirality yet the concept has not been highlighted much. Clear benefits with chiral molecules have been documented for various drug molecules few amongst them being anaesthetics, antihypertensives, antidepressants. Benefits of S-metoprolol over racemate are also clear in terms of responder rates, dose of administration and adverse effects profile in various cardiovascular diseases. Chirality is a good way forward in providing a new drug molecule which is safe with lesser pharmacokinetic and pharmacodynamics variability, lesser side effects and more potent action. S-metoprolol is chirally pure form of racemate metoprolol and has lesser side effects, is safer in patients of COPD and Diabetes who also have hypertension and comparable responder rates at half the doses when compared to racemate.

Metal-Ion-Mediated Supramolecular Chirality of l-Phenylalanine Based Hydrogels.

PubMed

Wang, Fang; Feng, Chuan-Liang

2018-05-14

For chiral hydrogels and related applications, one of the critical issues is how to control the chirality of supramolecular systems in an efficient way, including easy operation, efficient transfer of chirality, and so on. Herein, supramolecular chirality of l-phenylalanine based hydrogels can be effectively controlled by using a broad range of metal ions. The degree of twisting (twist pitch) and the diameter of the chiral nanostructures can also be efficiently regulated. These are ascribed to the synergic effect of hydrogen bonding and metal ion coordination. This study may develop a method to design a new class of electronically, optically, and biologically active materials. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Observation of the chiral magnetic effect in ZrTe₅

DOE PAGES

Li, Qiang; Kharzeev, Dmitri E.; Zhang, Cheng; ...

2015-02-08

The chiral magnetic effect is the generation of electric current induced by chirality imbalance in the presence of magnetic field. It is a macroscopic manifestation of the quantum anomaly in relativistic field theory of chiral fermions (massless spin 1/2 particles with a definite projection of spin on momentum) – a dramatic phenomenon arising from a collective motion of particles and antiparticles in the Dirac sea. The recent discovery of Dirac semimetals with chiral quasi-particles opens a fascinating possibility to study this phenomenon in condensed matter experiments. Here we report on the first observation of chiral magnetic effect through the measurementmore » of magneto-transport in zirconium pentatelluride, ZrTe₅. Our angle-resolved photoemission spectroscopy experiments show that this material’s electronic structure is consistent with a 3D Dirac semimetal. We observe a large negative magnetoresistance when magnetic field is parallel with the current. The measured quadratic field dependence of the magnetoconductance is a clear indication of the chiral magnetic effect. Furthermore, the observed phenomenon stems from the effective transmutation of Dirac semimetal into a Weyl semimetal induced by the parallel electric and magnetic fields that represent a topologically nontrivial gauge field background.« less

The chiral magnetic effect and chiral symmetry breaking in SU(3) quenched lattice gauge theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Braguta, V. V., E-mail: braguta@mail.ru; Buividovich, P. V., E-mail: buividovich@itep.ru; Kalaydzhyan, T., E-mail: tigran.kalaydzhyan@desy.de

2012-04-15

We study some properties of the non-Abelian vacuum induced by strong external magnetic field. We perform calculations in the quenched SU(3) lattice gauge theory with tadpole-improved Luescher-Weisz action and chirally invariant lattice Dirac operator. The following results are obtained: The chiral symmetry breaking is enhanced by the magnetic field. The chiral condensate depends on the strength of the applied field as a power function with exponent {nu} = 1.6 {+-} 0.2. There is a paramagnetic polarization of the vacuum. The corresponding susceptibility and other magnetic properties are calculated and compared with the theoretical estimations. There are nonzero local fluctuations ofmore » the chirality and electromagnetic current, which grow with the magnetic field strength. These fluctuations can be a manifestation of the Chiral Magnetic Effect.« less

Spin-Wave Chirality and Its Manifestations in Antiferromagnets

NASA Astrophysics Data System (ADS)

Proskurin, Igor; Stamps, Robert L.; Ovchinnikov, Alexander S.; Kishine, Jun-ichiro

2017-10-01

As first demonstrated by Tang and Cohen in chiral optics, the asymmetry in the rate of electromagnetic energy absorption between left and right enantiomers is determined by an optical chirality density. Here, we demonstrate that this effect can exist in magnetic spin systems. By constructing a formal analogy with electrodynamics, we show that in antiferromagnets with broken chiral symmetry, the asymmetry in local spin-wave energy absorption is proportional to a spin-wave chirality density, which is a direct counterpart of optical zilch. We propose that injection of a pure spin current into an antiferromagnet may serve as a chiral symmetry breaking mechanism, since its effect in the spin-wave approximation can be expressed in terms of additional Lifshitz invariants. We use linear response theory to show that the spin current induces a nonequilibrium spin-wave chirality density.

Experimental results on chiral magnetic and vortical effects

DOE PAGES

Wang, Gang; Wen, Liwen

2017-01-12

Various novel transport phenomena in chiral systems result from the interplay of quantum anomalies with magnetic field and vorticity in high-energy heavy-ion collisions and could survive the expansion of the fireball and be detected in experiments. Among them are the chiral magnetic effect, the chiral vortical effect, and the chiral magnetic wave, the experimental searches for which have aroused extensive interest. As a result, the goal of this review is to describe the current status of experimental studies at Relativistic Heavy-Ion Collider at BNL and the Large Hadron Collider at CERN and to outline the future work in experiment neededmore » to eliminate the existing uncertainties in the interpretation of the data.« less

Investigating the nature of chiral near-field interactions

NASA Astrophysics Data System (ADS)

Barr, Lauren E.; Horsley, Simon A. R.; Hooper, Ian R.; Eager, Jake K.; Gallagher, Cameron P.; Hornett, Samuel M.; Hibbins, Alastair P.; Hendry, Euan

2018-04-01

In recent years, there have been reports of enhanced chiroptical interactions in the near-fields of antennas, postulated to be mediated by high spatial gradients in the electromagnetic fields. Here, using gigahertz experimentation, we investigate the nature of the chiral near-field generated by an array of staggered-rod antennas through its interaction with an array of aligned, subwavelength metallic helices. This allows us to eliminate many potential origins of enhancements, such as those associated with plasmon-exciton interactions, and search solely for enhancements due to the high spatial gradients in the chirality of the fields around chiral antennas (so-called `superchiral fields'). By comparing the strength of the chiral interaction with our helices to that of a homogeneous chiral layer with effective material parameters, we find that the strength of this chiral interaction can be predicted using a completely local effective medium approximation. This suggests no obvious enhancement in the chiral interaction in the near-field and indicates that nonlocal interactions are negligible in this system.

Second-order dissipative hydrodynamics for plasma with chiral asymmetry and vorticity

NASA Astrophysics Data System (ADS)

Gorbar, E. V.; Rybalka, D. O.; Shovkovy, I. A.

2017-05-01

By making use of the chiral kinetic theory in the relaxation-time approximation, we derive an Israel-Stewart type formulation of the hydrodynamic equations for a chiral relativistic plasma made of neutral particles (e.g., neutrinos). The effects of chiral asymmetry are captured by including an additional continuity equation for the axial charge, as well as the leading-order quantum corrections due to the spin of particles. In a formulation of the chiral kinetic theory used, we introduce a symmetric form of the energy-momentum tensor that is suitable for the description of a weakly nonuniform chiral plasma. By construction, the energy and momentum are conserved to the same leading order in the Planck constant as the kinetic equation itself. By making use of such a chiral kinetic theory and the Chapman-Enskog approach, we obtain a set of second-order dissipative hydrodynamic equations. The effects of the fluid vorticity and velocity fluctuations on the dispersion relations of chiral vortical waves are analyzed.

Enantioselective Effects of Chiral Pesticides on their Primary Targets and Secondary Targets.

PubMed

Yang, Ye; Zhang, Jianyun; Yao, Yijun

2017-01-01

Enantioselectivity has been well recognized in the environmental fate and effects of chiral pesticides. Enantiospecific action of the optical enantiomers on the biological molecules establishes the mechanistic basis for the enantioselective toxicity of chiral pesticides to both target and non-target organisms. We undertook a structured search of bibliographic databases for research literature concerning the enantioselective effects of chiral pesticides, including insecticides, herbicides and fungicides, on biomolecules in various species by using some key words. The results of the relevant literatures were reviewed in the text and summarized in tables. Pesticides generally exert their activity on the target organisms via disrupting the primary target biomolecules. In non-target species, effects of pesticides on the secondary targets distinguished from the primary ones make great contribution to their toxicity. Recent investigations have provided convincing evidence of enantioselective toxicity of chiral pesticides to both target and non-target species which is recognized to result from their enantiospecific action on the primary or secondary targets in organisms. This review confirms that chiral pesticides have enantiospecific effects on both primary and secondary target biomolecules in organisms. Future studies regarding toxicological effects of chiral pesticides should focus on the relationship between the enantiomeric difference in the compound-biomolecules interaction and the enantioselectivity in their toxicity.

IR properties of chiral effects in pionic matter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Avdoshkin, A.; Sadofyev, A. V.; Zakharov, V. I.

Chiral effects exhibit peculiar universality in idealized theoretical limits. However, they are known to be infrared sensitive and get modified in more realistic settings. In this work we study how the corresponding conductivities vary with the constituent mass. We concentrate on a pionic realization of chiral effects which provides a better control over infrared properties of the theory. The pionic medium is considered at finite vector and axial isospin chemical potentials in the presence of an external magnetic field. This system supports electric and axial isospin currents along the magnetic field which correspond to chiral magnetic and chiral separation effects.more » We show that these currents are sensitive to the finite mass of the constituents but the conductivities follow a simple scaling with the corresponding charge densities as one would expect for polarization effects. It is argued that this relation can capture the dependence of chiral effects on other infrared parameters. Finally, we briefly comment on the realization of the ’t Hooft matching condition in pionic media at finite densities.« less

IR properties of chiral effects in pionic matter

DOE PAGES

Avdoshkin, A.; Sadofyev, A. V.; Zakharov, V. I.

2018-04-27

Chiral effects exhibit peculiar universality in idealized theoretical limits. However, they are known to be infrared sensitive and get modified in more realistic settings. In this work we study how the corresponding conductivities vary with the constituent mass. We concentrate on a pionic realization of chiral effects which provides a better control over infrared properties of the theory. The pionic medium is considered at finite vector and axial isospin chemical potentials in the presence of an external magnetic field. This system supports electric and axial isospin currents along the magnetic field which correspond to chiral magnetic and chiral separation effects.more » We show that these currents are sensitive to the finite mass of the constituents but the conductivities follow a simple scaling with the corresponding charge densities as one would expect for polarization effects. It is argued that this relation can capture the dependence of chiral effects on other infrared parameters. Finally, we briefly comment on the realization of the ’t Hooft matching condition in pionic media at finite densities.« less

Circularly polarized guided modes in dielectrically chiral photonic crystal fiber.

PubMed

Li, Junqing; Su, Qiyao; Cao, Yusheng

2010-08-15

The effect of dielectric chirality on the polarization states and mode indices of guided modes in photonic crystal fiber (PCF) is investigated by a modified plane-wave expansion (PWE) method. Using a solid-core chiral PCF as a numerical example, we show that circular polarization is the eigenstate of the fundamental mode. Mode index divergence between right-handed circularly polarized (RCP) and left-handed circularly polarized (LCP) states is demonstrated. Chirality's effect on mode index and circular birefringence (CB) in such a PCF is found to be similar to that in bulk chiral media.

Chirality-induced negative refraction in magnetized plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guo, B.

2013-09-15

Characteristic equations in magnetized plasma with chirality are derived in simple formulations and the dispersion relations for propagation parallel and perpendicular to the external magnetic field are studied in detail. With the help of the dispersion relations of each eigenwave, the author explores chirality-induced negative refraction in magnetized plasma and investigates the effects of parameters (i.e., chirality degree, external magnetic field, etc.) on the negative refraction. The results show that the chirality is the necessary and only one factor which leads to negative refraction without manipulating electrical permittivity and magnetic permeability. Both increasing the degree of chirality and reducing themore » external magnetic field can result in greater range negative refraction. Parameter dependence of the effects is calculated and discussed.« less

Self-Assembly and Electrostriction of Arrays and Chains of Hopfion Particles in Chiral Liquid Crystals

DOE PAGES

Ackerman, P. J.; van de Lagemaat, J.; Smalyukh, I. I.

2015-01-21

Some of the most exotic condensed matter phases, such as twist grain boundary and blue phases in liquid crystals and Abrikosov phases in superconductors, contain arrays of topological defects in their ground state. Comprised of a triangular lattice of double-twist tubes of magnetization, the so-called ‘A-phase’ in chiral magnets is an example of a thermodynamically stable phase with topologically nontrivial solitonic field configurations referred to as two-dimensional skyrmions, or baby-skyrmions. Here we report that three-dimensional skyrmions in the form of double-twist tori called ‘hopfions’, or ‘torons’ when accompanied by additional self-compensating defects, self-assemble into periodic arrays and linear chains thatmore » exhibit electrostriction. In confined chiral nematic liquid crystals, this self-assembly is similar to that of liquid crystal colloids and originates from long-range elastic interactions between particle-like skyrmionic torus knots of molecular alignment field, which can be tuned from isotropic repulsive to weakly or highly anisotropic attractive by low-voltage electric fields.« less

Chiral electroweak currents in nuclei

DOE PAGES

Riska, D. O.; Schiavilla, R.

2017-01-10

Here, the development of the chiral dynamics based description of nuclear electroweak currents is reviewed. Gerald E. (Gerry) Brown’s role in basing theoretical nuclear physics on chiral Lagrangians is emphasized. Illustrative examples of the successful description of electroweak observables of light nuclei obtained from chiral effective field theory are presented.

Chiral magnetic effect in condensed matter systems

NASA Astrophysics Data System (ADS)

Li, Qiang; Kharzeev, Dmitri E.

2016-12-01

The chiral magnetic effect (CME) is the generation of electrical current induced by chirality imbalance in the presence of magnetic field. It is a macroscopic manifestation of the quantum chiral anomaly [S. L. Adler. Axial-vector vertex in spinor electrodynamics. Physical Review, 177, 2426 (1969), J. S. Bell and R. Jackiw. A PCAC puzzle: π 0 γγin the σ-model. Il Nuovo Cimento A, 60, 47-61 (1969)] in systems possessing charged chiral fermions. In quark-gluon plasma containing nearly massless quarks, the chirality imbalance is sourced by the topological transitions. In condensed matter systems, the chiral quasiparticles emerge in gapless semiconductors with two energy bands having pointlike degeneracies opening the path to the study of chiral anomaly [H. B. Nielsen and M. Ninomiya. The Adler-Bell-Jackiw anomaly and Weyl fermions in a crystal. Physics Letters B, 130, 389-396 (1983)]. Recently, these novel materials - so-called Dirac and Weyl semimetals have been discovered experimentally, are suitable for the investigation of the CME in condensed matter experiments. Here we report on the first experimental observation of the CME in a 3D Dirac semimetal ZrTe5 [Q. Li, D. E. Kharzeev, C. Zhang, Y. Huang, I. Pletikosić, A. V. Fedorov, R. D. Zhong, J. A. Schneeloch, G. D. Gu, and T. Valla. Chiral magnetic effect in ZrTe5. Nature Physics (2016) doi:10.1038/nphys3648].

Enantiomeric separation of six chiral pesticides that contain chiral sulfur/phosphorus atoms by supercritical fluid chromatography.

PubMed

Zhang, Lijun; Miao, Yelong; Lin, Chunmian

2018-03-01

Six chiral pesticides containing chiral sulfur/phosphorus atoms were separated by supercritical fluid chromatography with supercritical CO 2 as the main mobile phase component. The effect of the chiral stationary phase, different type and concentration of modifiers, column temperature, and backpressure on the separation efficiency was investigated to obtain the appropriate separation condition. Five chiral pesticides (isofenphos-methyl, isocarbophos, flufiprole, fipronil, and ethiprole) were baseline separated under experimental conditions, while isofenphos only obtained partial separation. The Chiralpak AD-3 column showed a better chiral separation ability than others for chiral pesticides containing chiral sulfur/phosphorus atoms. When different modifiers at the same concentration were used, the retention factor of pesticides except flufiprole decreased in the order of isopropanol, ethanol, methanol; meanwhile, the retention factor of flufiprole increased in the order of isopropanol, ethanol, methanol. For a given modifier, the retention factor and resolution decreased on the whole with the increase of its concentration. The enantiomer separation of five chiral pesticides was an "enthalpy-driven" process, and the separation factor decreased as the temperature increased. The backpressure of the mobile phase had little effect on the separation factor and resolution. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Synergistic effects on enantioselectivity of zwitterionic chiral stationary phases for separations of chiral acids, bases, and amino acids by HPLC.

PubMed

Hoffmann, Christian V; Pell, Reinhard; Lämmerhofer, Michael; Lindner, Wolfgang

2008-11-15

In an attempt to overcome the limited applicability scope of earlier proposed Cinchona alkaloid-based chiral weak anion exchangers (WAX) and recently reported aminosulfonic acid-based chiral strong cation exchangers (SCX), which are conceptionally restricted to oppositely charged solutes, their individual chiral selector (SO) subunits have been fused in a combinatorial synthesis approach into single, now zwitterionic, chiral SO motifs. The corresponding zwitterionic ion-exchange-type chiral stationary phases (CSPs) in fact combined the applicability spectra of the parent chiral ion exchangers allowing for enantioseparations of chiral acids and amine-type solutes in liquid chromatography using polar organic mode with largely rivaling separation factors as compared to the parent WAX and SCX CSPs. Furthermore, the application spectrum could be remarkably expanded to various zwitterionic analytes such as alpha- and beta-amino acids and peptides. A set of structurally related yet different CSPs consisting of either a quinine or quinidine alkaloid moiety as anion-exchange subunit and various chiral or achiral amino acids as cation-exchange subunits enabled us to derive structure-enantioselectivity relationships, which clearly provided strong unequivocal evidence for synergistic effects of the two oppositely charged ion-exchange subunits being involved in molecular recognition of zwitterionic analytes by zwitterionic SOs driven by double ionic coordination.

Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles

PubMed Central

Deng, Jun; Wu, Sai; Yao, Mengyun; Gao, Changyou

2016-01-01

Chirality is one of the ubiquitous phenomena in biological systems. The left handed (L-) amino acids and right handed (D-) sugars are normally found in proteins, and in RNAs and DNAs, respectively. The effect of chiral surfaces at the nanoscale on cellular uptake has, however, not been explored. This study reveals for the first time the molecular chirality on gold nanoparticles (AuNPs) functions as a direct regulator for cellular uptake. Monolayers of 2-mercaptoacetyl-L(D)-valine (L(D)-MAV) and poly(acryloyl-L(D)-valine (L(D)-PAV) chiral molecules were formed on AuNPs surface, respectively. The internalized amount of PAV-AuNPs was several times larger than that of MAV-AuNPs by A549 and HepG2 cells, regardless of the chirality difference. However, the D-PAV-AuNPs were internalized with significantly larger amount than the L-PAV-AuNPs. This chirality-dependent uptake effect is likely attributed to the preferable interaction between the L-phospholipid-based cell membrane and the D-enantiomers. PMID:27531648

Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles

NASA Astrophysics Data System (ADS)

Deng, Jun; Wu, Sai; Yao, Mengyun; Gao, Changyou

2016-08-01

Chirality is one of the ubiquitous phenomena in biological systems. The left handed (L-) amino acids and right handed (D-) sugars are normally found in proteins, and in RNAs and DNAs, respectively. The effect of chiral surfaces at the nanoscale on cellular uptake has, however, not been explored. This study reveals for the first time the molecular chirality on gold nanoparticles (AuNPs) functions as a direct regulator for cellular uptake. Monolayers of 2-mercaptoacetyl-L(D)-valine (L(D)-MAV) and poly(acryloyl-L(D)-valine (L(D)-PAV) chiral molecules were formed on AuNPs surface, respectively. The internalized amount of PAV-AuNPs was several times larger than that of MAV-AuNPs by A549 and HepG2 cells, regardless of the chirality difference. However, the D-PAV-AuNPs were internalized with significantly larger amount than the L-PAV-AuNPs. This chirality-dependent uptake effect is likely attributed to the preferable interaction between the L-phospholipid-based cell membrane and the D-enantiomers.

Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles.

PubMed

Deng, Jun; Wu, Sai; Yao, Mengyun; Gao, Changyou

2016-08-17

Chirality is one of the ubiquitous phenomena in biological systems. The left handed (L-) amino acids and right handed (D-) sugars are normally found in proteins, and in RNAs and DNAs, respectively. The effect of chiral surfaces at the nanoscale on cellular uptake has, however, not been explored. This study reveals for the first time the molecular chirality on gold nanoparticles (AuNPs) functions as a direct regulator for cellular uptake. Monolayers of 2-mercaptoacetyl-L(D)-valine (L(D)-MAV) and poly(acryloyl-L(D)-valine (L(D)-PAV) chiral molecules were formed on AuNPs surface, respectively. The internalized amount of PAV-AuNPs was several times larger than that of MAV-AuNPs by A549 and HepG2 cells, regardless of the chirality difference. However, the D-PAV-AuNPs were internalized with significantly larger amount than the L-PAV-AuNPs. This chirality-dependent uptake effect is likely attributed to the preferable interaction between the L-phospholipid-based cell membrane and the D-enantiomers.

Topological Magnon Bands in a Kagome Lattice Ferromagnet.

PubMed

Chisnell, R; Helton, J S; Freedman, D E; Singh, D K; Bewley, R I; Nocera, D G; Lee, Y S

2015-10-02

There is great interest in finding materials possessing quasiparticles with topological properties. Such materials may have novel excitations that exist on their boundaries which are protected against disorder. We report experimental evidence that magnons in an insulating kagome ferromagnet can have a topological band structure. Our neutron scattering measurements further reveal that one of the bands is flat due to the unique geometry of the kagome lattice. Spin wave calculations show that the measured band structure follows from a simple Heisenberg Hamiltonian with a Dzyaloshinkii-Moriya interaction. This serves as the first realization of an effectively two-dimensional topological magnon insulator--a new class of magnetic material that should display both a magnon Hall effect and protected chiral edge modes.

In situ synthesis of di-n-butyl l-tartrate-boric acid complex chiral selector and its application in chiral microemulsion electrokinetic chromatography.

PubMed

Hu, Shaoqiang; Chen, Yonglei; Zhu, Huadong; Zhu, Jinhua; Yan, Na; Chen, Xingguo

2009-11-06

A novel procedure for in situ assembling a complex chiral selector, di-n-butyl l-tartrate-boric acid complex, by the reaction of di-n-butyl l-tartrate with boric acid in a running buffer was reported and its application in the enantioseparation of beta-blockers and structural related compounds by chiral microemulsion electrokinetic chromatography (MEEKC) has been demonstrated. In order to achieve a good enantioseparation, the effect of dibutyl l-tartrate and sodium tetraborate concentration, surfactant identity and concentration, cosurfactant, buffer pH and composition, organic modifiers, as well as applied voltage and capillary length were investigated. Ten pairs of enantiomers that could not be separated with only dibutyl l-tartrate, obtained good chiral separation using the complex chiral selector; among them, seven pairs could be baseline resolved under optimized experimental conditions. The fixation of chiral centers by the formation of five-membered rings, and being oppositely charged with basic analytes were thought to be the key factors giving the complex chiral selector a superior chiral recognition capability. The effect of the molecular structure of analytes on enantioseparation was discussed in terms of molecular interaction.

Single walled boron nitride nanotube-based biosensor: an atomistic finite element modelling approach.

PubMed

Panchal, Mitesh B; Upadhyay, Sanjay H

2014-09-01

The unprecedented dynamic characteristics of nanoelectromechanical systems make them suitable for nanoscale mass sensing applications. Owing to superior biocompatibility, boron nitride nanotubes (BNNTs) are being increasingly used for such applications. In this study, the feasibility of single walled BNNT (SWBNNT)-based bio-sensor has been explored. Molecular structural mechanics-based finite element (FE) modelling approach has been used to analyse the dynamic behaviour of SWBNNT-based biosensors. The application of an SWBNNT-based mass sensing for zeptogram level of mass has been reported. Also, the effect of size of the nanotube in terms of length as well as different chiral atomic structures of SWBNNT has been analysed for their sensitivity analysis. The vibrational behaviour of SWBNNT has been analysed for higher-order modes of vibrations to identify the intermediate landing position of biological object of zeptogram scale. The present molecular structural mechanics-based FE modelling approach is found to be very effectual to incorporate different chiralities of the atomic structures. Also, different boundary conditions can be effectively simulated using the present approach to analyse the dynamic behaviour of the SWBNNT-based mass sensor. The presented study has explored the potential of SWBNNT, as a nanobiosensor having the capability of zeptogram level mass sensing.

Self-assembly of skyrmion-dressed chiral nematic colloids with tangential anchoring.

PubMed

Pandey, M B; Porenta, T; Brewer, J; Burkart, A; Copar, S; Zumer, S; Smalyukh, Ivan I

2014-06-01

We describe dipolar nematic colloids comprising mutually bound solid microspheres, three-dimensional skyrmions, and point defects in a molecular alignment field of chiral nematic liquid crystals. Nonlinear optical imaging and numerical modeling based on minimization of Landau-de Gennes free energy reveal that the particle-induced skyrmions resemble torons and hopfions, while matching surface boundary conditions at the interfaces of liquid crystal and colloidal spheres. Laser tweezers and videomicroscopy reveal that the skyrmion-colloidal hybrids exhibit purely repulsive elastic pair interactions in the case of parallel dipoles and an unexpected reversal of interaction forces from repulsive to attractive as the center-to-center distance decreases for antiparallel dipoles. The ensuing elastic self-assembly gives rise to colloidal chains of antiparallel dipoles with particles entangled by skyrmions.

Quantized Chiral Magnetic Current from Reconnections of Magnetic Flux.

PubMed

Hirono, Yuji; Kharzeev, Dmitri E; Yin, Yi

2016-10-21

We introduce a new mechanism for the chiral magnetic effect that does not require an initial chirality imbalance. The chiral magnetic current is generated by reconnections of magnetic flux that change the magnetic helicity of the system. The resulting current is entirely determined by the change of magnetic helicity, and it is quantized.

Chiral vortical effect generated by chiral anomaly in vortex-skyrmions

NASA Astrophysics Data System (ADS)

Volovik, G. E.

2017-03-01

We discuss the type of the general macroscopic parity-violating effects, when there is the current along the vortex, which is concentrated in the vortex core. We consider vortices in chiral superfluids with Weyl points. In the vortex core, the positions of the Weyl points form the skyrmion structure. We show that the mass current concentrated in such a core is provided by the spectral flow through the Weyl points according to the Adler-Bell-Jackiw equation for chiral anomaly.

Anomaly manifestation of Lieb-Schultz-Mattis theorem and topological phases

NASA Astrophysics Data System (ADS)

Cho, Gil Young; Hsieh, Chang-Tse; Ryu, Shinsei

2017-11-01

The Lieb-Schultz-Mattis (LSM) theorem dictates that emergent low-energy states from a lattice model cannot be a trivial symmetric insulator if the filling per unit cell is not integral and if the lattice translation symmetry and particle number conservation are strictly imposed. In this paper, we compare the one-dimensional gapless states enforced by the LSM theorem and the boundaries of one-higher dimensional strong symmetry-protected topological (SPT) phases from the perspective of quantum anomalies. We first note that they can both be described by the same low-energy effective field theory with the same effective symmetry realizations on low-energy modes, wherein non-on-site lattice translation symmetry is encoded as if it were an internal symmetry. In spite of the identical form of the low-energy effective field theories, we show that the quantum anomalies of the theories play different roles in the two systems. In particular, we find that the chiral anomaly is equivalent to the LSM theorem, whereas there is another anomaly that is not related to the LSM theorem but is intrinsic to the SPT states. As an application, we extend the conventional LSM theorem to multiple-charge multiple-species problems and construct several exotic symmetric insulators. We also find that the (3+1)d chiral anomaly provides only the perturbative stability of the gaplessness local in the parameter space.

Homochiral Evolution in Self-Assembled Chiral Polymers and Block Copolymers.

PubMed

Wen, Tao; Wang, Hsiao-Fang; Li, Ming-Chia; Ho, Rong-Ming

2017-04-18

The significance of chirality transfer is not only involved in biological systems, such as the origin of homochiral structures in life but also in man-made chemicals and materials. How the chiral bias transfers from molecular level (molecular chirality) to helical chain (conformational chirality) and then to helical superstructure or phase (hierarchical chirality) from self-assembly is vital for the chemical and biological processes in nature, such as communication, replication, and enzyme catalysis. In this Account, we summarize the methodologies for the examination of homochiral evolution at different length scales based on our recent studies with respect to the self-assembly of chiral polymers and chiral block copolymers (BCPs*). A helical (H*) phase to distinguish its P622 symmetry from that of normal hexagonally packed cylinder phase was discovered in the self-assembly of BCPs* due to the chirality effect on BCP self-assembly. Enantiomeric polylactide-containing BCPs*, polystyrene-b-poly(l-lactide) (PS-PLLA) and polystyrene-b-poly(d-lactide) (PS-PDLA), were synthesized for the examination of homochiral evolution. The optical activity (molecular chirality) of constituted chiral repeating unit in the chiral polylactide is detected by electronic circular dichroism (ECD) whereas the conformational chirality of helical polylactide chain can be explicitly determined by vibrational circular dichroism (VCD). The H* phases of the self-assembled polylactide-containing BCPs* can be directly visualized by 3D transmission electron microscopy (3D TEM) technique at which the handedness (hierarchical chirality) of the helical nanostructure is thus determined. The results from the ECD, VCD, and 3D TEM for the investigated chirality at different length scales suggest the homochiral evolution in the self-assembly of the BCPs*. For chiral polylactides, twisted lamellae in crystalline banded spherulite can be formed by dense packing scheme and effective interactions upon helical chains from self-assembly. The handedness of the twisted lamella can be determined by using rotation experiment of polarized light microscopy (PLM). Similar to the self-assembly of BCPs*, the examined results suggest the homochiral evolution in the crystallized chiral polylactides. The results presented in this Account demonstrate the notable progress in the spectral and morphological determination for the examination of molecular, conformational, and hierarchical chirality in self-assembled twisted superstructures of chiral polymers and helical phases of block copolymers and suggest the attainability of homochiral evolution in the self-assembly of chiral homopolymers and BCPs*. The suggested methodologies for the understanding of the mechanisms of the chirality transfer at different length scales provide the approaches to give Supporting Information for disclosing the mysteries of the homochiral evolution from molecular level.

Chirality in molecular collision dynamics

NASA Astrophysics Data System (ADS)

Lombardi, Andrea; Palazzetti, Federico

2018-02-01

Chirality is a phenomenon that permeates the natural world, with implications for atomic and molecular physics, for fundamental forces and for the mechanisms at the origin of the early evolution of life and biomolecular homochirality. The manifestations of chirality in chemistry and biochemistry are numerous, the striking ones being chiral recognition and asymmetric synthesis with important applications in molecular sciences and in industrial and pharmaceutical chemistry. Chiral discrimination phenomena, due to the existence of two enantiomeric forms, very well known in the case of interaction with light, but still nearly disregarded in molecular collision studies. Here we review some ideas and recent advances about the role of chirality in molecular collisions, designing and illustrating molecular beam experiments for the demonstration of chiral effects and suggesting a scenario for a stereo-directional origin of chiral selection.

Anatomy of the chiral magnetic effect in and out of equilibrium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kharzeev, Dmitri; Stephanov, Mikhail; Yee, Ho-Ung

Here, we identify a new contribution to the chiral magnetic conductivity at finite frequencies—the magnetization current. This allows us to quantitatively reproduce the known field-theoretic time-dependent (AC) chiral magnetic response in terms of kinetic theory. We also evaluate the corresponding AC chiral magnetic conductivity in two-flavor QCD plasma at weak coupling. The magnetization current results from the spin response of chiral quasiparticles to magnetic field, and is thus proportional to the quasiparticle’s g -factor. Furthemrore, in condensed matter systems, where the chiral quasiparticles are emergent and the g -factor can significantly differ from 2, this opens up the possibility ofmore » tuning the AC chiral magnetic response.« less

Anatomy of the chiral magnetic effect in and out of equilibrium

DOE PAGES

Kharzeev, Dmitri; Stephanov, Mikhail; Yee, Ho-Ung

2017-03-28

Here, we identify a new contribution to the chiral magnetic conductivity at finite frequencies—the magnetization current. This allows us to quantitatively reproduce the known field-theoretic time-dependent (AC) chiral magnetic response in terms of kinetic theory. We also evaluate the corresponding AC chiral magnetic conductivity in two-flavor QCD plasma at weak coupling. The magnetization current results from the spin response of chiral quasiparticles to magnetic field, and is thus proportional to the quasiparticle’s g -factor. Furthemrore, in condensed matter systems, where the chiral quasiparticles are emergent and the g -factor can significantly differ from 2, this opens up the possibility ofmore » tuning the AC chiral magnetic response.« less

Chiral photonic crystal fibers with single mode and single polarization

NASA Astrophysics Data System (ADS)

Li, She; Li, Junqing

2015-12-01

Chiral photonic crystal fiber (PCF) with a solid core is numerically investigated by a modified chiral plane-wave expansion method. The effects of structural parameters and chirality strength are analyzed on single-polarization single-mode range and polarization states of guided modes. The simulation demonstrates that the chiral photonic crystal fiber compared to its achiral counterpart possesses another single-circular-polarization operation range, which is located in the short-wavelength region. The original single-polarization operation range in the long-wavelength region extends to the short wavelength caused by introducing chirality. Then this range becomes a broadened one with elliptical polarization from linear polarization. With increase of chirality, the two single-polarization single-mode ranges may fuse together. By optimizing the structure, an ultra-wide single-circular-polarization operation range from 0.5 μm to 1.67 μm for chiral PCF can be realized with moderate chirality strength.

Second Harmonic Generation Optical Rotation Solely Attributable to Chirality in Plasmonic Metasurfaces.

PubMed

Collins, Joel T; Hooper, David C; Mark, Andrew G; Kuppe, Christian; Valev, Ventsislav Kolev

2018-05-31

Chiral plasmonic nanostructures, those lacking mirror symmetry, can be designed to manipulate the polarization of incident light resulting in chiroptical (chiral optical) effects such as circular dichroism (CD) and optical rotation (OR). Due to high symmetry sensitivity, corresponding effects in second harmonic generation (SHG-CD and SHG-OR) are typically much stronger in comparison. These nonlinear effects have long been used for chiral molecular analysis and characterization, however both linear and nonlinear optical rotation can occur even in achiral structures, if the structure is birefringent due to anisotropy. Crucially, chiroptical effects resulting from anisotropy typically exhibit a strong dependence on structural orientation. Here we report large second-harmonic generation optical rotation of ±45°, due to intrinsic chirality in a highly anisotropic helical metamaterial. The SHG intensity is found to strongly relate to the structural anisotropy, however the angle of SHG-OR is invariant under sample rotation. We show that by tuning the geometry of anisotropic nanostructures, the interaction between anisotropy, chirality, and experiment geometry can allow even greater control over the chiroptical properties of plasmonic metamaterials.

Experimental Evidence of Chiral Ferrimagnetism in Amorphous GdCo Films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Streubel, Robert; Lambert, Charles-Henri; Kent, Noah

Inversion symmetry breaking has become a vital research area in modern magnetism with phenomena including the Rashba effect, spin Hall effect, and the Dzyaloshinskii-Moriya interaction (DMI)-a vector spin exchange. The latter one may stabilize chiral spin textures with topologically nontrivial properties, such as Skyrmions. So far, chiral spin textures have mainly been studied in helimagnets and thin ferromagnets with heavy-element capping. Here, the concept of chirality driven by interfacial DMI is generalized to complex multicomponent systems and demonstrated on the example of chiral ferrimagnetism in amorphous GdCo films. Utilizing Lorentz microscopy and X-ray magnetic circular dichroism spectroscopy, and tailoring thickness,more » capping, and rare-earth composition, reveal that 2 nm thick GdCo films preserve ferrimagnetism and stabilize chiral domain walls. Finally, the type of chiral domain walls depends on the rare-earth composition/saturation magnetization, enabling a possible temperature control of the intrinsic properties of ferrimagnetic domain walls.« less

Experimental Evidence of Chiral Ferrimagnetism in Amorphous GdCo Films

DOE PAGES

Streubel, Robert; Lambert, Charles-Henri; Kent, Noah; ...

2018-05-23

Inversion symmetry breaking has become a vital research area in modern magnetism with phenomena including the Rashba effect, spin Hall effect, and the Dzyaloshinskii-Moriya interaction (DMI)-a vector spin exchange. The latter one may stabilize chiral spin textures with topologically nontrivial properties, such as Skyrmions. So far, chiral spin textures have mainly been studied in helimagnets and thin ferromagnets with heavy-element capping. Here, the concept of chirality driven by interfacial DMI is generalized to complex multicomponent systems and demonstrated on the example of chiral ferrimagnetism in amorphous GdCo films. Utilizing Lorentz microscopy and X-ray magnetic circular dichroism spectroscopy, and tailoring thickness,more » capping, and rare-earth composition, reveal that 2 nm thick GdCo films preserve ferrimagnetism and stabilize chiral domain walls. Finally, the type of chiral domain walls depends on the rare-earth composition/saturation magnetization, enabling a possible temperature control of the intrinsic properties of ferrimagnetic domain walls.« less

Use of Chiral Oxazolidinones for a Multi-Step Synthetic Laboratory Module

ERIC Educational Resources Information Center

Betush, Matthew P.; Murphree, S. Shaun

2009-01-01

Chiral oxazolidinone chemistry is used as a framework for an advanced multi-step synthesis lab. The cost-effective and robust preparation of chiral starting materials is presented, as well as the use of chiral auxiliaries in a synthesis scheme that is appropriate for students currently in the second semester of the organic sequence. (Contains 1…

Bolometric-Effect-Based Wavelength-Selective Photodetectors Using Sorted Single Chirality Carbon Nanotubes

PubMed Central

Zhang, Suoming; Cai, Le; Wang, Tongyu; Shi, Rongmei; Miao, Jinshui; Wei, Li; Chen, Yuan; Sepúlveda, Nelson; Wang, Chuan

2015-01-01

This paper exploits the chirality-dependent optical properties of single-wall carbon nanotubes for applications in wavelength-selective photodetectors. We demonstrate that thin-film transistors made with networks of carbon nanotubes work effectively as light sensors under laser illumination. Such photoresponse was attributed to photothermal effect instead of photogenerated carriers and the conclusion is further supported by temperature measurements. Additionally, by using different types of carbon nanotubes, including a single chirality (9,8) nanotube, the devices exhibit wavelength-selective response, which coincides well with the absorption spectra of the corresponding carbon nanotubes. This is one of the first reports of controllable and wavelength-selective bolometric photoresponse in macroscale assemblies of chirality-sorted carbon nanotubes. The results presented here provide a viable route for achieving bolometric-effect-based photodetectors with programmable response spanning from visible to near-infrared by using carbon nanotubes with pre-selected chiralities. PMID:26643777

Chiral helimagnetic state in a Kondo lattice model with the Dzyaloshinskii-Moriya interaction

NASA Astrophysics Data System (ADS)

Okumura, Shun; Kato, Yasuyuki; Motome, Yukitoshi

2018-05-01

Monoaxial chiral magnets can form a noncollinear twisted spin structure called the chiral helimagnetic state. We study magnetic properties of such a chiral helimagnetic state, with emphasis on the effect of itinerant electrons. Modeling a monoaxial chiral helimagnet by a one-dimensional Kondo lattice model with the Dzyaloshinskii-Moriya interaction, we perform a variational calculation to elucidate the stable spin configuration in the ground state. We obtain a chiral helimagnetic state as a candidate for the ground state, whose helical pitch is modulated by the model parameters: the Kondo coupling, the Dzyaloshinski-Moriya interaction, and electron filling.

Spin-Dependent Transport through Chiral Molecules Studied by Spin-Dependent Electrochemistry

PubMed Central

2016-01-01

Conspectus Molecular spintronics (spin + electronics), which aims to exploit both the spin degree of freedom and the electron charge in molecular devices, has recently received massive attention. Our recent experiments on molecular spintronics employ chiral molecules which have the unexpected property of acting as spin filters, by way of an effect we call “chiral-induced spin selectivity” (CISS). In this Account, we discuss new types of spin-dependent electrochemistry measurements and their use to probe the spin-dependent charge transport properties of nonmagnetic chiral conductive polymers and biomolecules, such as oligopeptides, L/D cysteine, cytochrome c, bacteriorhodopsin (bR), and oligopeptide-CdSe nanoparticles (NPs) hybrid structures. Spin-dependent electrochemical measurements were carried out by employing ferromagnetic electrodes modified with chiral molecules used as the working electrode. Redox probes were used either in solution or when directly attached to the ferromagnetic electrodes. During the electrochemical measurements, the ferromagnetic electrode was magnetized either with its magnetic moment pointing “UP” or “DOWN” using a permanent magnet (H = 0.5 T), placed underneath the chemically modified ferromagnetic electrodes. The spin polarization of the current was found to be in the range of 5–30%, even in the case of small chiral molecules. Chiral films of the l- and d-cysteine tethered with a redox-active dye, toludin blue O, show spin polarizarion that depends on the chirality. Because the nickel electrodes are susceptible to corrosion, we explored the effect of coating them with a thin gold overlayer. The effect of the gold layer on the spin polarization of the electrons ejected from the electrode was investigated. In addition, the role of the structure of the protein on the spin selective transport was also studied as a function of bias voltage and the effect of protein denaturation was revealed. In addition to “dark” measurements, we also describe photoelectrochemical measurements in which light is used to affect the spin selective electron transport through the chiral molecules. We describe how the excitation of a chromophore (such as CdSe nanoparticles), which is attached to a chiral working electrode, can flip the preferred spin orientation of the photocurrent, when measured under the identical conditions. Thus, chirality-induced spin polarization, when combined with light and magnetic field effects, opens new avenues for the study of the spin transport properties of chiral molecules and biomolecules and for creating new types of spintronic devices in which light and molecular chirality provide new functions and properties. PMID:27797176

Chiral Magnetic Effect in Heavy Ion Collisions

DOE PAGES

Liao, Jinfeng

2016-12-01

The Chiral Magnetic Effect (CME) is a remarkable phenomenon that stems from highly nontrivial interplay of QCD chiral symmetry, axial anomaly, and gluonic topology. We show it is of fundamental importance to search for the CME in experiments. The heavy ion collisions provide a unique environment where a hot chiral-symmetric quark-gluon plasma is created, gluonic topological fluctuations generate chirality imbalance, and very strong magnetic fields |Β →|~m 2 π are present during the early stage of such collisions. Significant efforts have been made to look for CME signals in heavy ion collision experiments. Lastly, in this contribution we give amore » brief overview on the status of such efforts.« less

Chirality-induced magnon transport in AA-stacked bilayer honeycomb chiral magnets.

PubMed

Owerre, S A

2016-11-30

In this Letter, we study the magnetic transport in AA-stacked bilayer honeycomb chiral magnets coupled either ferromagnetically or antiferromagnetically. For both couplings, we observe chirality-induced gaps, chiral protected edge states, magnon Hall and magnon spin Nernst effects of magnetic spin excitations. For ferromagnetically coupled layers, thermal Hall and spin Nernst conductivities do not change sign as function of magnetic field or temperature similar to single-layer honeycomb ferromagnetic insulator. In contrast, for antiferromagnetically coupled layers, we observe a sign change in the thermal Hall and spin Nernst conductivities as the magnetic field is reversed. We discuss possible experimental accessible honeycomb bilayer quantum materials in which these effects can be observed.

Spin Chirality of Cu3 and V3 Nanomagnets. 1. Rotation Behavior of Vector Chirality, Scalar Chirality, and Magnetization in the Rotating Magnetic Field, Magnetochiral Correlations.

PubMed

Belinsky, Moisey I

2016-05-02

The rotation behavior of the vector chirality κ, scalar chirality χ, and magnetization M in the rotating magnetic field H1 is considered for the V3 and Cu3 nanomagnets, in which the Dzialoshinsky-Moriya coupling is active. The polar rotation of the field H1 of the given strength H1 results in the energy spectrum characterized by different vector and scalar chiralities in the ground and excited states. The magnetochiral correlations between the vector and scalar chiralities, energy, and magnetization in the rotating field were considered. Under the uniform polar rotation of the field H1, the ground-state chirality vector κI performs sawtooth oscillations and the magnetization vector MI performs the sawtooth oscillating rotation that is accompanied by the correlated transformation of the scalar chirality χI. This demonstrates the magnetochiral effect of the joint rotation behavior and simultaneous frustrations of the spin chiralities and magnetization in the rotating field, which are governed by the correlation between the chiralities and magnetization.

Neuronal growth on L- and D-cysteine self-assembled monolayers reveals neuronal chiral sensitivity.

PubMed

Baranes, Koby; Moshe, Hagay; Alon, Noa; Schwartz, Shmulik; Shefi, Orit

2014-05-21

Studying the interaction between neuronal cells and chiral molecules is fundamental for the design of novel biomaterials and drugs. Chirality influences all biological processes that involve intermolecular interaction. One common method used to study cellular interactions with different enantiomeric targets is the use of chiral surfaces. Based on previous studies that demonstrated the importance of cysteine in the nervous system, we studied the effect of L- and D-cysteine on single neuronal growth. L-Cysteine, which normally functions as a neuromodulator or a neuroprotective antioxidant, causes damage at elevated levels, which may occur post trauma. In this study, we grew adult neurons in culture enriched with L- and D-cysteine as free compounds or as self-assembled monolayers of chiral surfaces and examined the effect on the neuronal morphology and adhesion. Notably, we have found that exposure to the L-cysteine enantiomer inhibited, and even prevented, neuronal attachment more severely than exposure to the D-cysteine enantiomer. Atop the L-cysteine surfaces, neuronal growth was reduced and degenerated. Since the cysteine molecules were attached to the surface via the thiol groups, the neuronal membrane was exposed to the molecular chiral site. Thus, our results have demonstrated high neuronal chiral sensitivity, revealing chiral surfaces as indirect regulators of neuronal cells and providing a reference for studying chiral drugs.

Chirality as a tool in nucleic acid recognition: principles and relevance in biotechnology and in medicinal chemistry.

PubMed

Corradini, Roberto; Sforza, Stefano; Tedeschi, Tullia; Marchelli, Rosangela

2007-05-05

The understanding of the interaction of chiral species with DNA or RNA is very important for the development of new tools in biology and of new drugs. Several cases in which chirality is a crucial point in determining the DNA binding mode are reviewed and discussed, with the aim of illustrating how chirality can be considered as a tool for improving the understanding of mechanisms and the effectiveness of nucleic acid recognition. The review is divided into two parts: the former describes examples of chiral species interacting with DNA: intercalators, metal complexes, and groove binders; the latter part is dedicated to chirality in DNA analogs, with discussion of phosphate stereochemistry and chirality of ribose substitutes, in particular of peptide nucleic acids (PNAs) for which a number of works have been published recently dealing with the effect of chirality in DNA recognition. The discussion is intended to show how enantiomeric recognition originates at the molecular level, by exploiting the enormous progresses recently achieved in the field of structural characterization of complexes formed by nucleic acid with their ligands by crystallographic and spectroscopic methods. Examples of application of the DNA binding molecules described and the role of chirality in DNA recognition relevant for biotechnology or medicinal chemistry are reported. (c) 2007 Wiley-Liss, Inc.

A novel aggregation-induced emission enhancement triggered by the assembly of a chiral gelator: from non-emissive nanofibers to emissive micro-loops.

PubMed

Chen, Wenrui; Qing, Guangyan; Sun, Taolei

2016-12-22

In this study, a novel aggregation-induced emission (AIE) enhancement triggered by the self-assembly of chiral gelator is described. Tuning of molecular chirality in situ triggers different assemblies of superstructures exhibiting fluorescence. This novel AIE material can constitute an emerging library of chiral supramolecules for turn-on fluorescent sensors. It will also help in better understanding the effects of chiral factors on the photophysical process.

Maltodextrins as chiral selectors in CE: molecular structure effect of basic chiral compounds on the enantioseparation.

PubMed

Tabani, Hadi; Fakhari, Ali Reza; Nojavan, Saeed

2014-10-01

Prediction of chiral separation for a compound using a chiral selector is an interesting and debatable work. For this purpose, in this study 23 chiral basic drugs with different chemical structures were selected as model solutes and the influence of their chemical structures on the enantioseparation in the presence of maltodextrin (MD) as chiral selector was investigated. For chiral separation, a 100-mM phosphate buffer solution (pH 3.0) containing 10% (w/v) MD with dextrose equivalent (DE) of 4-7 as chiral selector at the temperature of 25°C and voltage of 20 kV was used. Under this condition, baseline separation was achieved for nine chiral compounds and partial separation was obtained for another six chiral compounds while no enantioseparation was obtained for the remaining eight compounds. The results showed that the existence of at least two aromatic rings or cycloalkanes and an oxygen or nitrogen atom or -CN group directly bonded to the chiral center are necessary for baseline separation. With the obtained results in this study, chiral separation of a chiral compound can be estimated with MD-modified capillary electrophoresis before analysis. This prediction will minimize the number of preliminary experiments required to resolve enantiomers and will save time and cost. © 2014 Wiley Periodicals, Inc.

Exact results for the star lattice chiral spin liquid

NASA Astrophysics Data System (ADS)

Kells, G.; Mehta, D.; Slingerland, J. K.; Vala, J.

2010-03-01

We examine the star lattice Kitaev model whose ground state is a chiral spin liquid. We fermionize the model such that the fermionic vacua are toric-code states on an effective Kagome lattice. This implies that the Abelian phase of the system is inherited from the fermionic vacua and that time-reversal symmetry is spontaneously broken at the level of the vacuum. In terms of these fermions we derive the Bloch-matrix Hamiltonians for the vortex-free sector and its time-reversed counterpart and illuminate the relationships between the sectors. The phase diagram for the model is shown to be a sphere in the space of coupling parameters around the triangles of the lattices. The Abelian phase lies inside the sphere and the critical boundary between topologically distinct Abelian and non-Abelian phases lies on the surface. Outside the sphere the system is generically gapped except in the planes where the coupling parameters between the vertices on triangles are zero. These cases correspond to bipartite lattice structures and the dispersion relations are similar to that of the original Kitaev honeycomb model. In a further analysis we demonstrate the threefold non-Abelian ground-state degeneracy on a torus by explicit calculation.

Application of L-proline derivatives as chiral shift reagents for enantiomeric recognition of carboxylic acids.

PubMed

Naziroglu, Hayriye Nevin; Durmaz, Mustafa; Bozkurt, Selahattin; Sirit, Abdulkadir

2011-07-01

Four proline-derived chiral receptors 5-8 were readily synthesized starting from L-proline. The enantiomeric recognition ability of chiral receptors was examined with a series of carboxylic acids by (1) H NMR spectroscopy. The molar ratio and the association constants of the chiral compounds with each of the enantiomers of guest molecules were determined by using Job plots and a nonlinear least-squares fitting method, respectively. The Job plots indicate that the hosts form 1:1 instantaneous complexes with all guests. The receptors exhibited different chiral recognition abilities toward the enantiomers of racemic guests. Among the chiral receptors used in this study, prolinamide 6 was found to be the best chiral shift reagent and is effective for the determination of the enantiomeric excess of chiral carboxylic acids. Copyright © 2011 Wiley-Liss, Inc.

Proposed Spontaneous Generation of Magnetic Fields by Curved Layers of a Chiral Superconductor

NASA Astrophysics Data System (ADS)

Kvorning, T.; Hansson, T. H.; Quelle, A.; Smith, C. Morais

2018-05-01

We demonstrate that two-dimensional chiral superconductors on curved surfaces spontaneously develop magnetic flux. This geometric Meissner effect provides an unequivocal signature of chiral superconductivity, which could be observed in layered materials under stress. We also employ the effect to explain some puzzling questions related to the location of zero-energy Majorana modes.

Molecular recognition in chiral smectic liquid crystals: the effect of core-core interactions and chirality transfer on polar order.

PubMed

Lemieux, Robert P

2007-12-01

This critical review focuses on the induction of polar order in smectic liquid crystal phases by dopants with axially chiral cores, and should be of interest to all practitioners of supramolecular chemistry. The variations in polarization power of these dopants with the core structure of the liquid crystal hosts is a manifestation of molecular recognition that reflects the nanosegregation of aromatic cores from paraffinic side-chains in smectic phases, and the collective effect of core-core interactions that enable the propagation of chiral perturbations.

Uncertainty analysis of 208Pb neutron skin predictions with chiral interactions

DOE PAGES

Sammarruca, Francesca

2015-09-14

Here, we report predictions for the neutron skin in 208Pb using chiral two- and three-body interactions at increasing orders of chiral effective field theory and varying resolution scales. Closely related quantities, such as the slope of the symmetry energy, are also discussed. As a result, the sensitivity of the skin to just pure neutron matter pressure when going from order 2 to order 4 of chiral effective theory is singled out in a set of calculations that employ an empirical equation of state for symmetric nuclear matter.

Chirality in adsorption on solid surfaces.

PubMed

Zaera, Francisco

2017-12-07

In the present review we survey the main advances made in recent years on the understanding of chemical chirality at solid surfaces. Chirality is an important topic, made particularly relevant by the homochiral nature of the biochemistry of life on Earth, and many chiral chemical reactions involve solid surfaces. Here we start our discussion with a description of surface chirality and of the different ways that chirality can be bestowed on solid surfaces. We then expand on the studies carried out to date to understand the adsorption of chiral compounds at a molecular level. We summarize the work published on the adsorption of pure enantiomers, of enantiomeric mixtures, and of prochiral molecules on chiral and achiral model surfaces, especially on well-defined metal single crystals but also on other flat substrates such as highly ordered pyrolytic graphite. Several phenomena are identified, including surface reconstruction and chiral imprinting upon adsorption of chiral agents, and the enhancement or suppression of enantioselectivity seen in some cases upon adsorption of enantiomixtures of chiral compounds. The possibility of enhancing the enantiopurity of adsorbed layers upon the addition of chiral seeds and the so-called "sergeants and soldiers" phenomenon are presented. Examples are provided where the chiral behavior has been associated with either thermodynamic or kinetic driving forces. Two main approaches to the creation of enantioselective surface sites are discussed, namely, via the formation of supramolecular chiral ensembles made out of small chiral adsorbates, and by adsorption of more complex chiral molecules capable of providing suitable chiral environments for reactants by themselves, via the formation of individual adsorbate:modifier adducts on the surface. Finally, a discussion is offered on the additional effects generated by the presence of the liquid phase often required in practical applications such as enantioselective crystallization, chiral chromatography, and enantioselective catalysis.

Blue phase liquid crystal phase transition for cyano compound chiral nematic liquid crystal mixtures with three two-ring core structures and chiral dopant concentrations

NASA Astrophysics Data System (ADS)

Shin, Jaesun; Kim, Beomjong; Jung, Wansu; Fahad, Mateen; Park, SangJin; Hong, Sung-Kyu

2017-05-01

Blue phase (BP) temperature range of a chiral nematic liquid crystal (LC) mixture is dependent upon the host nematic LC chemical structure and chiral dopant concentration. In this study, we investigated BP phase transition behaviour and helical twisting power (HTP) using three chiral dopant concentrations of cyano compound chiral nematic LC mixtures incorporating three two-ring core structures in the host nematic LCs. The effect of the host nematic LC core structure, HTP and chiral dopant concentrations were considered on BP temperature ranges, for two types of complete BPI and BPII without isotropic phase (Iso) and two types of coexistence state of BPI+Iso and BPII+Iso.

Direct measurement of proximity-induced magnetism at the interface between a topological insulator and a ferromagnet

DOE PAGES

Lee, Changmin; Katmis, Ferhat; Jarillo-Herrero, Pablo; ...

2016-06-27

When a topological insulator (TI) is in contact with a ferromagnet, both time-reversal and inversion symmetries are broken at the interface. An energy gap is formed at the TI surface, and its electrons gain a net magnetic moment through short-range exchange interactions. Magnetic TIs can host various exotic quantum phenomena, such as massive Dirac fermions, Majorana fermions, the quantum anomalous Hall effect and chiral edge currents along the domain boundaries. However, selective measurement of induced magnetism at the buried interface has remained a challenge. Using magnetic second-harmonic generation, we directly probe both the in-plane and out-of-plane magnetizations induced at themore » interface between the ferromagnetic insulator (FMI) EuS and the three-dimensional TI Bi 2Se 3. Furthermore, our findings not only allow characterizing magnetism at the TI–FMI interface but also lay the groundwork for imaging magnetic domains and domain boundaries at the magnetic TI surfaces.« less

Chiral-selective nonlinear optical generation and emission control with plasmonic metamaterials (Conference Presentation)

NASA Astrophysics Data System (ADS)

Cai, Wenshan

2016-09-01

Metamaterials can be designed to exhibit extraordinarily strong chiral responses. Here we present a chiral metamaterial that produces both distinguishable linear and nonlinear features in the visible to near-infrared range. In additional to the gigantic chiral effects in the linear regime, the metamaterial demonstrates a pronounced contrast between second harmonic responses from the two circular polarizations. Linear and nonlinear images probed with circularly polarized lights show strongly defined contrast. Moreover, the chiral centers of the nanometallic structures with enhanced hotspots can be purposely opened for direct access, where emitters occupying the light-confining regions produce chiral-selective enhancement of two-photon luminescence.

Enantioselective induction of cytotoxicity by o,p'-DDD in PC12 cells: implications of chirality in risk assessment of POPs metabolites.

PubMed

Wang, Cui; Li, Zhuoyu; Zhang, Quan; Zhao, Meirong; Liu, Weiping

2013-04-16

The increased release of chiral persistent organic pollutants (POPs) into the environment has resulted in more attention to the role of enantioselectivity in the fate and ecotoxicological effects of these compounds. Although the enantioselectivity of chiral POPs has been considered in previous studies, little effort has been expended to discern the enantiospecific effects of chiral POPs metabolites, which may impede comprehensive risk assessments of these chemicals. In the present study, o,p'-DDD, the chiral metabolite of o,p'-DDT, was used as a model chiral metabolite. First, a preferential chiral separation at 100% ethanol was employed to obtain a pure enantiomer. The enantioselective cytotoxicity of o,p'-DDD in rat cells (PC12) was evaluated by detecting activation of the cellular apoptosis and oxidative stress systems and microarray analysis. We have documented for the first time that R-(+)-o,p'-DDD increases apoptosis by selectively disturbing the oxidative system (enzymes and molecules) and regulating the transcription of Aven, Bid, Cideb and Tp53. By comparing the data from the present study to data derived from the parent compound, we concluded that the R-enantiomer is the more detrimental stereostructure for both o,p'-DDT and o,p'-DDD. This observed stereostructural effect is in line with the structure-activity relationship formulated at other structural levels. Biological activities of the chiral metabolites are likely to occur in the same absolute configuration between chiral POPs and their metabolites provided that they have the similar stereostructures.

Enantiopure heterobimetallic single-chain magnets from the chiral Ru(III) building block.

PubMed

Ru, Jing; Gao, Feng; Wu, Tao; Yao, Min-Xia; Li, Yi-Zhi; Zuo, Jing-Lin

2014-01-21

A pair of one-dimensional enantiomers based on the versatile chiral dicyanoruthenate(III) building block have been synthesized and they are chiral single-chain magnets with the effective spin-reversal barrier of 28.2 K.

Five chiral Cd(II) complexes with dual chiral components: Effect of positional isomerism, luminescence and SHG response

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Lin, E-mail: lcheng@seu.edu.cn; Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University, Nanjing 211189; Wang, Jun

2015-01-15

Five chiral Cd(II) complexes with dual chiral components have been synthesized by using a series of (1R,2R)–N{sup 1},N{sup 2}-bis(pyridinylmethyl)cyclohexane-1,2-diamine ligands with different N-positions of pyridyl rings and Cd(NO{sub 3}){sub 2}. The circular dichroism (CD) spectra and second-harmonic generation (SHG) efficiency measurements confirmed that they are of structural chirality in the bulk samples. The luminescent properties indicated that they may have potential applications as optical materials. The formation of discrete mononuclear and binuclear complexes, and one-dimensional chains may be attributed to positional isomerism of the ligands. - Graphical abstract: Five chiral Cd(II) complexes with dual chiral components have been synthesized bymore » using a series of chiral ligands with different N-positions of pyridyl rings. - Highlights: • Five chiral Cd(II) complexes with dual chiral components have been synthesized. • CD spectra and SHG efficiency of the bulk samples have been measured. • The complexes display luminescent properties.« less

Chiral superconductors.

PubMed

Kallin, Catherine; Berlinsky, John

2016-05-01

Chiral superconductivity is a striking quantum phenomenon in which an unconventional superconductor spontaneously develops an angular momentum and lowers its free energy by eliminating nodes in the gap. It is a topologically non-trivial state and, as such, exhibits distinctive topological modes at surfaces and defects. In this paper we discuss the current theory and experimental results on chiral superconductors, focusing on two of the best-studied systems, Sr2RuO4, which is thought to be a chiral triplet p-wave superconductor, and UPt3, which has two low-temperature superconducting phases (in zero magnetic field), the lower of which is believed to be chiral triplet f-wave. Other systems that may exhibit chiral superconductivity are also discussed. Key signatures of chiral superconductivity are surface currents and chiral Majorana modes, Majorana states in vortex cores, and the possibility of half-flux quantum vortices in the case of triplet pairing. Experimental evidence for chiral superconductivity from μSR, NMR, strain, polar Kerr effect and Josephson tunneling experiments are discussed.

Dissolution of topological Fermi arcs in a dirty Weyl semimetal

NASA Astrophysics Data System (ADS)

Slager, Robert-Jan; Juričić, Vladimir; Roy, Bitan

2017-11-01

Weyl semimetals (WSMs) have recently attracted a great deal of attention as they provide a condensed matter realization of chiral anomaly, feature topologically protected Fermi arc surface states, and sustain sharp chiral Weyl quasiparticles up to a critical disorder at which a continuous quantum phase transition (QPT) drives the system into a metallic phase. We here numerically demonstrate that with increasing strength of disorder, the Fermi arc gradually loses its sharpness, and close to the WSM-metal QPT it completely dissolves into the metallic bath of the bulk. The predicted topological nature of the WSM-metal QPT and the resulting bulk-boundary correspondence across this transition can be directly observed in angle-resolved photoemission spectroscopy (ARPES) and Fourier transformed scanning tunneling microscopy (STM) measurements by following the continuous deformation of the Fermi arcs with increasing disorder in recently discovered Weyl materials.

Chirality detection of enantiomers using twisted optical metamaterials

NASA Astrophysics Data System (ADS)

Zhao, Yang; Askarpour, Amir N.; Sun, Liuyang; Shi, Jinwei; Li, Xiaoqin; Alù, Andrea

2017-01-01

Many naturally occurring biomolecules, such as amino acids, sugars and nucleotides, are inherently chiral. Enantiomers, a pair of chiral isomers with opposite handedness, often exhibit similar physical and chemical properties due to their identical functional groups and composition, yet show different toxicity to cells. Detecting enantiomers in small quantities has an essential role in drug development to eliminate their unwanted side effects. Here we exploit strong chiral interactions with plasmonic metamaterials with specifically designed optical response to sense chiral molecules down to zeptomole levels, several orders of magnitude smaller than what is typically detectable with conventional circular dichroism spectroscopy. In particular, the measured spectra reveal opposite signs in the spectral regime directly associated with different chiral responses, providing a way to univocally assess molecular chirality. Our work introduces an ultrathin, planarized nanophotonic interface to sense chiral molecules with inherently weak circular dichroism at visible and near-infrared frequencies.

Chirality detection of enantiomers using twisted optical metamaterials

PubMed Central

Zhao, Yang; Askarpour, Amir N.; Sun, Liuyang; Shi, Jinwei; Li, Xiaoqin; Alù, Andrea

2017-01-01

Many naturally occurring biomolecules, such as amino acids, sugars and nucleotides, are inherently chiral. Enantiomers, a pair of chiral isomers with opposite handedness, often exhibit similar physical and chemical properties due to their identical functional groups and composition, yet show different toxicity to cells. Detecting enantiomers in small quantities has an essential role in drug development to eliminate their unwanted side effects. Here we exploit strong chiral interactions with plasmonic metamaterials with specifically designed optical response to sense chiral molecules down to zeptomole levels, several orders of magnitude smaller than what is typically detectable with conventional circular dichroism spectroscopy. In particular, the measured spectra reveal opposite signs in the spectral regime directly associated with different chiral responses, providing a way to univocally assess molecular chirality. Our work introduces an ultrathin, planarized nanophotonic interface to sense chiral molecules with inherently weak circular dichroism at visible and near-infrared frequencies. PMID:28120825

Chirality Transfer in Gold(I)-Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study

PubMed Central

Barker, Graeme; Johnson, David G; Young, Paul C; Macgregor, Stuart A; Lee, Ai-Lan

2015-01-01

Gold(I)-catalysed direct allylic etherifications have been successfully carried out with chirality transfer to yield enantioenriched, γ-substituted secondary allylic ethers. Our investigations include a full substrate-scope screen to ascertain substituent effects on the regioselectivity, stereoselectivity and efficiency of chirality transfer, as well as control experiments to elucidate the mechanistic subtleties of the chirality-transfer process. Crucially, addition of molecular sieves was found to be necessary to ensure efficient and general chirality transfer. Computational studies suggest that the efficiency of chirality transfer is linked to the aggregation of the alcohol nucleophile around the reactive π-bound Au–allylic ether complex. With a single alcohol nucleophile, a high degree of chirality transfer is predicted. However, if three alcohols are present, alternative proton transfer chain mechanisms that erode the efficiency of chirality transfer become competitive. PMID:26248980

Chiral anomaly, Berry phase, and chiral kinetic theory from worldlines in quantum field theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mueller, Niklas; Venugopalan, Raju

Here, we outline a novel chiral kinetic theory framework for systematic computations of the Chiral Magnetic Effect (CME) in ultrarelativistic heavy-ion collisions. The real part of the fermion determinant in the QCD effective action is expressed as a supersymmetric world-line action of spinning, colored, Grassmanian point particles in background gauge fields, with equations of motion that are covariant generalizations of the Bargmann-Michel-Telegdi and Wong equations. Berry’s phase is obtained in a consistent non-relativistic adiabatic limit. The chiral anomaly, in contrast, arises from the phase of the fermion determinant; its topological properties are therefore distinct from those of the Berry phase.more » We show that the imaginary contribution to the fermion determinant too can be expressed as a point particle world-line path integral and derive the corresponding anomalous axial vector current. Our results can be used to derive a covariant relativistic chiral kinetic theory including the effects of topological fluctuations that has overlap with classical-statistical simulations of the CME at early times and anomalous hydrodynamics at late times.« less

Out-of-equilibrium chiral magnetic effect from chiral kinetic theory

NASA Astrophysics Data System (ADS)

Huang, Anping; Jiang, Yin; Shi, Shuzhe; Liao, Jinfeng; Zhuang, Pengfei

2018-02-01

Recently there has been significant interest in the macroscopic manifestation of chiral anomaly in many-body systems of chiral fermions. A notable example is the Chiral Magnetic Effect (CME). Enthusiastic efforts have been made to search for the CME in the quark-gluon plasma created in heavy ion collisions. A crucial challenge is that the extremely strong magnetic field in such collisions may last only for a brief moment and the CME current may have to occur at so early a stage that the quark-gluon matter is still far from thermal equilibrium. This thus requires modeling of the CME in an out-of-equilibrium setting. With the recently developed theoretical tool of chiral kinetic theory, we make a first phenomenological study of the CME-induced charge separation during the pre-thermal stage in heavy ion collisions. The effect is found to be very sensitive to the time dependence of the magnetic field and also influenced by the initial quark momentum spectrum as well as the relaxation time of the system evolution toward thermal equilibrium. Within the present approach, such pre-thermal charge separation is found to be modest.

Chiral anomaly, Berry phase, and chiral kinetic theory from worldlines in quantum field theory

DOE PAGES

Mueller, Niklas; Venugopalan, Raju

2018-03-21

Here, we outline a novel chiral kinetic theory framework for systematic computations of the Chiral Magnetic Effect (CME) in ultrarelativistic heavy-ion collisions. The real part of the fermion determinant in the QCD effective action is expressed as a supersymmetric world-line action of spinning, colored, Grassmanian point particles in background gauge fields, with equations of motion that are covariant generalizations of the Bargmann-Michel-Telegdi and Wong equations. Berry’s phase is obtained in a consistent non-relativistic adiabatic limit. The chiral anomaly, in contrast, arises from the phase of the fermion determinant; its topological properties are therefore distinct from those of the Berry phase.more » We show that the imaginary contribution to the fermion determinant too can be expressed as a point particle world-line path integral and derive the corresponding anomalous axial vector current. Our results can be used to derive a covariant relativistic chiral kinetic theory including the effects of topological fluctuations that has overlap with classical-statistical simulations of the CME at early times and anomalous hydrodynamics at late times.« less

Coriolis effect and spin Hall effect of light in an inhomogeneous chiral medium.

PubMed

Zhang, Yongliang; Shi, Lina; Xie, Changqing

2016-07-01

We theoretically investigate the spin Hall effect of spinning light in an inhomogeneous chiral medium. The Hamiltonian equations of the photon are analytically obtained within eikonal approximation in the noninertial orthogonal frame. Besides the usual spin curvature coupling, the chiral parameter enters the Hamiltonian as a spin-torsion-like interaction. We reveal that both terms have parallel geometric origins as the Coriolis terms of Maxwell's equations in nontrivial frames.

Chiral effective theory of dark matter direct detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bishara, Fady; Brod, Joachim; Grinstein, Benjamin

2017-02-01

We present the effective field theory for dark matter interactions with the visible sector that is valid at scales of O(1 GeV). Starting with an effective theory describing the interactions of fermionic and scalar dark matter with quarks, gluons and photons via higher dimension operators that would arise from dimension-five and dimension-six operators above electroweak scale, we perform a nonperturbative matching onto a heavy baryon chiral perturbation theory that describes dark matter interactions with light mesons and nucleons. This is then used to obtain the coefficients of the nuclear response functions using a chiral effective theory description of nuclear forces.more » Our results consistently keep the leading contributions in chiral counting for each of the initial Wilson coefficients.« less

Spectrum of the Wilson Dirac operator at finite lattice spacings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akemann, G.; Damgaard, P. H.; Splittorff, K.

2011-04-15

We consider the effect of discretization errors on the microscopic spectrum of the Wilson Dirac operator using both chiral perturbation theory and chiral random matrix theory. A graded chiral Lagrangian is used to evaluate the microscopic spectral density of the Hermitian Wilson Dirac operator as well as the distribution of the chirality over the real eigenvalues of the Wilson Dirac operator. It is shown that a chiral random matrix theory for the Wilson Dirac operator reproduces the leading zero-momentum terms of Wilson chiral perturbation theory. All results are obtained for a fixed index of the Wilson Dirac operator. The low-energymore » constants of Wilson chiral perturbation theory are shown to be constrained by the Hermiticity properties of the Wilson Dirac operator.« less

GLOBAL EFFECTS OF VARIOUS SOIL TREATMENTS ON TRANSFORMATIONS OF CHIRAL PESTICIDES

EPA Science Inventory

Many pesticides and other organic pollutants are chiral, and their enantiomers exhibit differences in biological properties, including rates of microbial degradation. We have measured by chiral GC and capillary electrophoresis the enantioselectivity of biodegradation of three pe...

One-step hydrothermal synthesis of chiral carbon dots and their effects on mung bean plant growth.

PubMed

Zhang, Mengling; Hu, Lulu; Wang, Huibo; Song, Yuxiang; Liu, Yang; Li, Hao; Shao, Mingwang; Huang, Hui; Kang, Zhenhui

2018-06-27

Chiral compounds/materials have important effects on the growth of plants. Chiral carbon dots (CDs), as an emerging chiral carbon nanomaterial, have great potential in bio-application and bio-nanotechnology. Herein, we report a hydrothermal method to synthesize chiral CDs from cysteine (cys) and citric acid. These chiral CDs were further demonstrated to have systemic effects on the growth of mung bean plants, in which case both l- and d-CDs can promote the growth of the root in mung bean plants, stem length of mung bean sprouts and water absorption of bean seeds. The elongation of mung bean sprouts presented an increasing trend with the treatment of chiral CDs of increasing concentration (below 500 μg mL-1). Furthermore, in the optimal concentration (100 μg mL-1), the l-CDs can improve root vigor and the activity of the Rubisco enzyme of bean sprouts by 8.4% and 20.5%, while the d-CDs increased by 28.9% and 67.5%. Due to more superior properties in improving root vigor and the activity of the Rubisco enzyme of mung bean sprouts, d-CDs are able to enhance photosynthesis better and accumulate more carbohydrate in mung bean plants.

Delocalization of charge and current in a chiral quasiparticle wave packet

NASA Astrophysics Data System (ADS)

Sarkar, Subhajit

2018-03-01

A chiral quasiparticle wave packet (c-QPWP) is defined as a conventional superposition of chiral quasiparticle states corresponding to an interacting electron system in two dimensions (2D) in the presence of Rashba spin-orbit coupling (RSOC). I investigate its internal structure via studying the charge and the current densities within the first-order perturbation in the electron-electron interaction. It is found that the c-QPWP contains a localized charge which is less than the magnitude of the bare charge and the remaining charge resides at the system boundary. The amount of charge delocalized turns out to be inversely proportional to the degenerate Fermi velocity v0(=√{α2+2 μ /m }) when RSOC (with strength α ) is weak, and therefore externally tunable. For strong RSOC, the magnitudes of both the delocalized charge and the current further strongly depend on the direction of propagation of the wave packet. Both the charge and the current densities consist of an anisotropic r-2 tail away from the center of the wave packet. Possible implications of such delocalizations in real systems corresponding to 2D semiconductor heterostructure are also discussed within the context of particle injection experiments.

Lattice QCD analysis for relation between quark confinement and chiral symmetry breaking

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doi, Takahiro M.; Suganuma, Hideo; Iritani, Takumi

2016-01-22

The Polyakov loop and the Dirac modes are connected via a simple analytical relation on the temporally odd-number lattice, where the temporal lattice size is odd with the normal (nontwisted) periodic boundary condition. Using this relation, we investigate the relation between quark confinement and chiral symmetry breaking in QCD. In this paper, we discuss the properties of this analytical relation and numerically investigate each Dirac-mode contribution to the Polyakov loop in both confinement and deconfinement phases at the quenched level. This relation indicates that low-lying Dirac modes have little contribution to the Polyakov loop, and we numerically confirmed this fact.more » From our analysis, it is suggested that there is no direct one-to-one corresponding between quark confinement and chiral symmetry breaking in QCD. Also, in the confinement phase, we numerically find that there is a new “positive/negative symmetry” in the Dirac-mode matrix elements of link-variable operator which appear in the relation and the Polyakov loop becomes zero because of this symmetry. In the deconfinement phase, this symmetry is broken and the Polyakov loop is non-zero.« less

Chiral discrimination in nuclear magnetic resonance spectroscopy

NASA Astrophysics Data System (ADS)

Lazzeretti, Paolo

2017-11-01

Chirality is a fundamental property of molecules whose spatial symmetry is characterized by the absence of improper rotations, making them not superimposable to their mirror image. Chiral molecules constitute the elementary building blocks of living species and one enantiomer is favoured in general (e.g. L-aminoacids and D-sugars pervade terrestrial homochiral biochemistry) because most chemical reactions producing natural substances are enantioselective. Since the effect of chiral chemicals and drugs on living beings can be markedly different between enantiomers, the quest for practical spectroscopical methods to scrutinize chirality is an issue of great importance and interest. Nuclear magnetic resonance (NMR) is a topmost analytical technique, but spectrometers currently used are ‘blind’ to chirality, i.e. unable to discriminate the two mirror-image forms of a chiral molecule, because, in the absence of a chiral solvent, the spectral parameters, chemical shifts and spin-spin coupling constants are identical for enantiomers. Therefore, the development of new procedures for routine chiral recognition would offer basic support to scientists. However, in the presence of magnetic fields, a distinction between true and false chirality is mandatory. The former epitomizes natural optical activity, which is rationalized by a time-even pseudoscalar, i.e. the trace of a second-rank tensor, the mixed electric dipole/magnetic dipole polarizability. The Faraday effect, magnetic circular dichroism and magnetic optical activity are instead related to a time-odd axial vector. The present review summarizes recent theoretical and experimental efforts to discriminate enantiomers via NMR spectroscopy, with the focus on the deep connection between chirality and symmetry properties under the combined set of fundamental discrete operations, namely charge conjugation, parity (space inversion) and time (motion) reversal.

Chiral Organic Cages with a Triple-Stranded Helical Structure Derived from Helicene.

PubMed

Malik, Abaid Ullah; Gan, Fuwei; Shen, Chengshuo; Yu, Na; Wang, Ruibin; Crassous, Jeanne; Shu, Mouhai; Qiu, Huibin

2018-02-28

We report the use of helicene with an intrinsic helical molecular structure to prepare covalent organic cages via imine condensation. The organic cages revealed a [3+2]-type architecture containing a triple-stranded helical structure with three helicene units arranged in a propeller-like fashion with the framework integrally twisted. Such structural chirality was retained upon dissolution in organic solvents, as indicated by a strong diastereotopy effect in proton NMR and unique Cotton effects in circular dichroism spectra. Further study on chiral adsorption showed that the chiral organic cages possess considerable enantioselectivity toward a series of aromatic racemates.

The Clusters-in-a-Liquid Approach for Solvation: New Insights from the Conformer Specific Gas Phase Spectroscopy and Vibrational Optical Activity Spectroscopy

PubMed Central

Perera, Angelo S.; Thomas, Javix; Poopari, Mohammad R.; Xu, Yunjie

2016-01-01

Vibrational optical activity spectroscopies, namely vibrational circular dichroism (VCD) and Raman optical activity (ROA), have been emerged in the past decade as powerful spectroscopic tools for stereochemical information of a wide range of chiral compounds in solution directly. More recently, their applications in unveiling solvent effects, especially those associated with water solvent, have been explored. In this review article, we first select a few examples to demonstrate the unique sensitivity of VCD spectral signatures to both bulk solvent effects and explicit hydrogen-bonding interactions in solution. Second, we discuss the induced solvent chirality, or chiral transfer, VCD spectral features observed in the water bending band region in detail. From these chirality transfer spectral data, the related conformer specific gas phase spectroscopic studies of small chiral hydration clusters, and the associated matrix isolation VCD experiments of hydrogen-bonded complexes in cold rare gas matrices, a general picture of solvation in aqueous solution emerges. In such an aqueous solution, some small chiral hydration clusters, rather than the chiral solutes themselves, are the dominant species and are the ones that contribute mainly to the experimentally observed VCD features. We then review a series of VCD studies of amino acids and their derivatives in aqueous solution under different pHs to emphasize the importance of the inclusion of the bulk solvent effects. These experimental data and the associated theoretical analyses are the foundation for the proposed “clusters-in-a-liquid” approach to account for solvent effects effectively. We present several approaches to identify and build such representative chiral hydration clusters. Recent studies which applied molecular dynamics simulations and the subsequent snapshot averaging approach to generate the ROA, VCD, electronic CD, and optical rotatory dispersion spectra are also reviewed. Challenges associated with the molecular dynamics snapshot approach are discussed and the successes of the seemingly random “ad hoc explicit solvation” reported before are also explained. To further test and improve the “clusters-in-a-liquid” model in practice, future work in terms of conformer specific gas phase spectroscopy of sequential solvation of a chiral solute, matrix isolation VCD measurements of small chiral hydration clusters, and more sophisticated models for the bulk solvent effects would be highly valuable. PMID:26942177

Chiroptical studies on supramolecular chirality of molecular aggregates.

PubMed

Sato, Hisako; Yajima, Tomoko; Yamagishi, Akihiko

2015-10-01

The attempts of applying chiroptical spectroscopy to supramolecular chirality are reviewed with a focus on vibrational circular dichroism (VCD). Examples were taken from gels, solids, and monolayers formed by low-molecular mass weight chiral gelators. Particular attention was paid to a group of gelators with perfluoroalkyl chains. The effects of the helical conformation of the perfluoroalkyl chains on the formation of chiral architectures are reported. It is described how the conformation of a chiral gelator was determined by comparing the experimental and theoretical VCD spectra together with a model proposed for the molecular aggregation in fibrils. The results demonstrate the potential utility of the chiroptical method in analyzing organized chiral aggregates. © 2015 Wiley Periodicals, Inc.

Observation of chiral phonons

NASA Astrophysics Data System (ADS)

Zhu, Hanyu; Yi, Jun; Li, Ming-Yang; Xiao, Jun; Zhang, Lifa; Yang, Chih-Wen; Kaindl, Robert A.; Li, Lain-Jong; Wang, Yuan; Zhang, Xiang

2018-02-01

Chirality reveals symmetry breaking of the fundamental interaction of elementary particles. In condensed matter, for example, the chirality of electrons governs many unconventional transport phenomena such as the quantum Hall effect. Here we show that phonons can exhibit intrinsic chirality in monolayer tungsten diselenide. The broken inversion symmetry of the lattice lifts the degeneracy of clockwise and counterclockwise phonon modes at the corners of the Brillouin zone. We identified the phonons by the intervalley transfer of holes through hole-phonon interactions during the indirect infrared absorption, and we confirmed their chirality by the infrared circular dichroism arising from pseudoangular momentum conservation. The chiral phonons are important for electron-phonon coupling in solids, phonon-driven topological states, and energy-efficient information processing.

Chirality, Metallicity, and Transition Dependent Asymmetries in Resonance Raman Excitation Profiles of Chirality-Enriched Carbon Nanotubes

NASA Astrophysics Data System (ADS)

Doorn, Stephen; Duque, Juan; Telg, Hagen; Haroz, Erik; Tu, Xiaomin; Zheng, Ming

2014-03-01

Access to carbon nanotube samples enriched in single chiralities allows the observation of new photophysical behaviors obscured or difficult to demonstrate in mixed-chirality ensembles. Recent examples include the observation of strongly asymmetric G-band excitation profiles resulting from non-Condon effects1 and the unambiguous demonstration of Raman interference effects.2 We present here our most recent results demonstrating the generality of the non-Condon behavior to include metallic species (specifically several armchair chiralities). Additionally, the Eii dependence in non-Condon behavior with excitations from E11 thru E44 for both RBM and G modes will be discussed. 1. J.G. Duque, et. al., ACS Nano, 5, 5233 (2011). 2. J.G. Duque, et. al., Phys. Rev. Lett. 108, 117404 (2012).

Chiral anomaly, Berry phase, and chiral kinetic theory from worldlines in quantum field theory

NASA Astrophysics Data System (ADS)

Mueller, Niklas; Venugopalan, Raju

2018-03-01

In previous work, we outlined a worldline framework that can be used for systematic computations of the chiral magnetic effect (CME) in ultrarelativistic heavy-ion collisions. Towards this end, we first expressed the real part of the fermion determinant in the QCD effective action as a supersymmetric worldline action of spinning, colored, Grassmanian point particles in background gauge fields, with equations of motion that are covariant generalizations of the Bargmann-Michel-Telegdi and Wong equations. The chiral anomaly, in contrast, arises from the phase of the fermion determinant. Remarkably, the latter too can be expressed as a point particle worldline path integral, which can be employed to derive the anomalous axial vector current. We will show here how Berry's phase can be obtained in a consistent nonrelativistic adiabatic limit of the real part of the fermion determinant. Our work provides a general first principles demonstration that the topology of Berry's phase is distinct from that of the chiral anomaly confirming prior arguments by Fujikawa in specific contexts. This suggests that chiral kinetic treatments of the CME in heavy-ion collisions that include Berry's phase alone are incomplete. We outline the elements of a worldline covariant relativistic chiral kinetic theory that captures the physics of how the chiral current is modified by many-body scattering and topological fluctuations.

Molecular dynamics simulation of a nanofluidic energy absorption system: effects of the chiral vector of carbon nanotubes.

PubMed

Ganjiani, Sayed Hossein; Hossein Nezhad, Alireza

2018-02-14

A Nanofluidic Energy Absorption System (NEAS) is a novel nanofluidic system with a small volume and weight. In this system, the input mechanical energy is converted to surface tension energy during liquid infiltration in the nanotube. The NEAS is made of a mixture of nanoporous material particles in a functional liquid. In this work, the effects of the chiral vector of a carbon nanotube (CNT) on the performance characteristics of the NEAS are investigated by using molecular dynamics simulation. For this purpose, six CNTs with different diameters for each type of armchair, zigzag and chiral, and several chiral CNTs with different chiral vectors (different values of indices (m,n)) are selected and studied. The results show that in the chiral CNTs, the contact angle shows the hydrophobicity of the CNT, and infiltration pressure is reduced by increasing the values of m and n (increasing the CNT diameter). Contact angle and infiltration pressure are decreased by almost 1.4% and 9% at all diameters, as the type of CNT is changed from chiral to zigzag and then to armchair. Absorbed energy density and efficiency are also decreased by increasing m and n and by changing the type of CNT from chiral to zigzag and then to armchair.

Electroclinic effect in the chiral lamellar α phase of a lyotropic liquid crystal

NASA Astrophysics Data System (ADS)

Harjung, Marc D.; Giesselmann, Frank

2018-03-01

In thermotropic chiral Sm -A* phases, an electric field along the smectic layers breaks the D∞ symmetry of the Sm -A* phase and induces a tilt of the liquid crystal director. This so-called electroclinic effect (ECE) was first reported by Garoff and Meyer in 1977 and attracted substantial scientific and technological interest due to its linear and submicrosecond electro-optic response [S. Garoff and R. B. Meyer, Phys. Rev. A 19, 338 (1979), 10.1103/PhysRevA.19.338]. We now report the observation of an ECE in the pretransitional regime from a lyotropic chiral lamellar Lα* phase into a lyo-Sm -C* phase, the lyotropic analog to the thermotropic Sm -C* phase which was recently discovered by Bruckner et al. [Angew. Chem. Int. Ed. 52, 8934 (2013), 10.1002/anie.201303344]. We further show that the observed ECE has all signatures of its thermotropic counterpart, namely (i) the effect is chiral in nature and vanishes in the racemic Lα phase, (ii) the effect is essentially linear in the sign and magnitude of the electric field, and (iii) the magnitude of the effect diverges hyperbolically as the temperature approaches the critical temperature of the second order tilting transition. Specific deviations between the ECEs in chiral lamellar and chiral smectic phases are related to the internal field screening effect of electric double layers formed by inevitable ionic impurities in lyotropic phases.

Effects of chiral three-nucleon forces on 4He-nucleus scattering in a wide range of incident energies

NASA Astrophysics Data System (ADS)

Toyokawa, Masakazu; Yahiro, Masanobu; Matsumoto, Takuma; Kohno, Michio

2018-02-01

An important current subject is to clarify the properties of chiral three-nucleon forces (3NFs) not only in nuclear matter but also in scattering between finite-size nuclei. Particularly for elastic scattering, this study has just started and the properties are not understood for a wide range of incident energies (E_in). We investigate basic properties of chiral 3NFs in nuclear matter with positive energies by using the Brueckner-Hartree-Fock method with chiral two-nucleon forces at N3LO and 3NFs at NNLO, and analyze the effects of chiral 3NFs on 4He elastic scattering from targets ^{208}Pb, ^{58}Ni, and ^{40}Ca over a wide range of 30 ≲ E_in/A_P ≲ 200 MeV by using the g-matrix folding model, where A_P is the mass number of the projectile. In symmetric nuclear matter with positive energies, chiral 3NFs make the single-particle potential less attractive and more absorptive. The effects mainly come from the Fujita-Miyazawa 2π-exchange 3NF and become slightly larger as E_in increases. These effects persist in the optical potentials of 4He scattering. As for the differential cross sections of 4He scattering, chiral-3NF effects are large for E_in/A_P ≳ 60 MeV and improve the agreement of the theoretical results with the measured ones. Particularly for E_in/A_P ≳ 100 MeV, the folding model reproduces measured differential cross sections pretty well. Cutoff (Λ) dependence is investigated for both nuclear matter and 4He scattering by considering two cases of Λ=450 and 550 MeV. The uncertainty coming from the dependence is smaller than chiral-3NF effects even at E_in/A_P=175 MeV.

Stoichiometry-Controlled Inversion of Supramolecular Chirality in Nanostructures Co-assembled with Bipyridines.

PubMed

Wang, Fang; Feng, Chuan-Liang

2018-02-01

To control supramolecular chirality of the co-assembled nanostructures, one of the remaining issues is how stoichiometry of the different molecules involved in co-assembly influence chiral transformation. Through co-assembly of achiral 1,4-bis(pyrid-4-yl)benzene and chiral phenylalanine-glycine derivative hydrogelators, stoichiometry is found to be an effective tool for controlling supramolecular chirality inversion processes. This inversion is mainly mediated by a delicate balance between intermolecular hydrogen bonding interactions and π-π stacking of the two components, which may subtly change the stacking of the molecules, in turn, the self-assembled nanostructures. This study exemplifies a simplistic way to invert the handedness of chiral nanostructures and provide fundamental understanding of the inherent principles of supramolecular chirality. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chirality controlled responsive self-assembled nanotubes in water† †Electronic supplementary information (ESI) available: Detailed experimental procedures and analyses, UV-vis absorption and CD spectroscopy, cryo-TEM and widefield microscopy. See DOI: 10.1039/c6sc02935c Click here for additional data file.

PubMed Central

van Dijken, D. J.; Štacko, P.; Stuart, M. C. A.; Browne, W. R.

2017-01-01

The concept of using chirality to dictate dimensions and to store chiral information in self-assembled nanotubes in a fully controlled manner is presented. We report a photoresponsive amphiphile that co-assembles with its chiral counterpart to form nanotubes and demonstrate how chirality can be used to effect the formation of either micrometer long, achiral nanotubes or shorter (∼300 nm) chiral nanotubes that are bundled. The nature of these assemblies is studied using a variety of spectroscopic and microscopic techniques and it is shown that the tubes can be disassembled with light, thereby allowing the chiral information to be erased. PMID:28451300

Lithium Enolates in the Enantioselective Construction of Tetrasubstituted Carbon Centers with Chiral Lithium Amides as Noncovalent Stereodirecting Auxiliaries.

PubMed

Yu, Kai; Lu, Ping; Jackson, Jeffrey J; Nguyen, Thuy-Ai D; Alvarado, Joseph; Stivala, Craig E; Ma, Yun; Mack, Kyle A; Hayton, Trevor W; Collum, David B; Zakarian, Armen

2017-01-11

Lithium enolates derived from carboxylic acids are ubiquitous intermediates in organic synthesis. Asymmetric transformations with these intermediates, a central goal of organic synthesis, are typically carried out with covalently attached chiral auxiliaries. An alternative approach is to utilize chiral reagents that form discrete, well-defined aggregates with lithium enolates, providing a chiral environment conducive of asymmetric bond formation. These reagents effectively act as noncovalent, or traceless, chiral auxiliaries. Lithium amides are an obvious choice for such reagents as they are known to form mixed aggregates with lithium enolates. We demonstrate here that mixed aggregates can effect highly enantioselective transformations of lithium enolates in several classes of reactions, most notably in transformations forming tetrasubstituted and quaternary carbon centers. Easy recovery of the chiral reagent by aqueous extraction is another practical advantage of this one-step protocol. Crystallographic, spectroscopic, and computational studies of the central reactive aggregate, which provide insight into the origins of selectivity, are also reported.

Directing the phase behavior of polyelectrolyte complexes using chiral patterned peptides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pacalin, Naomi M.; Leon, Lorraine; Tirrell, Matthew

Polyelectrolyte complexes (PECs) have a broad range of promising applications as soft materials due to their self-assembly and diversity of structure and chemical composition. Peptide polymer PECs are highly biocompatible and biodegradable, making them particularly useful for encapsulation of food additives and flavors, micellar drug delivery, medical and underwater adhesives, fetal membrane patches, and scaffolds for cell growth in tissue engineering. While parameters affecting PEC formation and stability in regards to charge effects are well researched, little is known about the effects of van der Waals interactions, hydrogen bonding, and secondary structure in these materials. Peptide chirality provides a uniquemore » opportunity to manipulate PEC phase to modulate the amount of solid-like (precipitate) or liquid-like (coacervate) character by influencing hydrogen bonding interactions among peptide chains. In previous work, we showed that chiral peptides form solid complexes, while complexes with even one racemic peptide were fluid. This raised the interesting question of how long a homochiral sequence must be to result in solid phase formation. In this work, we designed chiral patterned peptides of polyglutamic acid and polylysine ranging from 50 to 90% L-chiral residues with increasing numbers of sequential L-chiral residues before a chirality change. These polymers were mixed together to form PECs. We observed that 8 or more sequential L-chiral residues are necessary to achieve both the appearance of a precipitate phase and sustained beta-sheets in the complex, as determined by optical imaging and FTIR Spectroscopy. Less homochiral content results in formation of a coacervate phase. Thus, we show that chiral sequence can be used to control the phase transition of PECs. Understanding how to manipulate PEC phase using chiral sequence as presented here may enable tuning of the material properties to achieve the desired mechanical strength for coatings and polymer brushes, or the most effective molecular release kinetics for drug delivery applications, for example.« less

Directing the phase behavior of polyelectrolyte complexes using chiral patterned peptides

NASA Astrophysics Data System (ADS)

Pacalin, Naomi M.; Leon, Lorraine; Tirrell, Matthew

2016-10-01

Polyelectrolyte complexes (PECs) have a broad range of promising applications as soft materials due to their self-assembly and diversity of structure and chemical composition. Peptide polymer PECs are highly biocompatible and biodegradable, making them particularly useful for encapsulation of food additives and flavors, micellar drug delivery, medical and underwater adhesives, fetal membrane patches, and scaffolds for cell growth in tissue engineering. While parameters affecting PEC formation and stability in regards to charge effects are well researched, little is known about the effects of van der Waals interactions, hydrogen bonding, and secondary structure in these materials. Peptide chirality provides a unique opportunity to manipulate PEC phase to modulate the amount of solid-like (precipitate) or liquid-like (coacervate) character by influencing hydrogen bonding interactions among peptide chains. In previous work, we showed that chiral peptides form solid complexes, while complexes with even one racemic peptide were fluid. This raised the interesting question of how long a homochiral sequence must be to result in solid phase formation. In this work, we designed chiral patterned peptides of polyglutamic acid and polylysine ranging from 50 to 90% L-chiral residues with increasing numbers of sequential L-chiral residues before a chirality change. These polymers were mixed together to form PECs. We observed that 8 or more sequential L-chiral residues are necessary to achieve both the appearance of a precipitate phase and sustained β-sheets in the complex, as determined by optical imaging and FTIR Spectroscopy. Less homochiral content results in formation of a coacervate phase. Thus, we show that chiral sequence can be used to control the phase transition of PECs. Understanding how to manipulate PEC phase using chiral sequence as presented here may enable tuning of the material properties to achieve the desired mechanical strength for coatings and polymer brushes, or the most effective molecular release kinetics for drug delivery applications, for example.

Chiral corrections to the Adler-Weisberger sum rule

NASA Astrophysics Data System (ADS)

Beane, Silas R.; Klco, Natalie

2016-12-01

The Adler-Weisberger sum rule for the nucleon axial-vector charge, gA , offers a unique signature of chiral symmetry and its breaking in QCD. Its derivation relies on both algebraic aspects of chiral symmetry, which guarantee the convergence of the sum rule, and dynamical aspects of chiral symmetry breaking—as exploited using chiral perturbation theory—which allow the rigorous inclusion of explicit chiral symmetry breaking effects due to light-quark masses. The original derivations obtained the sum rule in the chiral limit and, without the benefit of chiral perturbation theory, made various attempts at extrapolating to nonvanishing pion masses. In this paper, the leading, universal, chiral corrections to the chiral-limit sum rule are obtained. Using PDG data, a recent parametrization of the pion-nucleon total cross sections in the resonance region given by the SAID group, as well as recent Roy-Steiner equation determinations of subthreshold amplitudes, threshold parameters, and correlated low-energy constants, the Adler-Weisberger sum rule is confronted with experimental data. With uncertainty estimates associated with the cross-section parametrization, the Goldberger-Treimann discrepancy, and the truncation of the sum rule at O (Mπ4) in the chiral expansion, this work finds gA=1.248 ±0.010 ±0.007 ±0.013 .

Net motion of acoustically levitating nano-particles: A theoretical analysis

NASA Astrophysics Data System (ADS)

Lippera, Kevin; Dauchot, Olivier; Benzaquen, Michael; Gulliver-LadHyX Collaboration

2017-11-01

A particle 2D-trapped in the nodal planed of a standing acoustic wave is prone to acoustic-phoretic motion as soon as its shape breaks polar or chiral symmetry. such a setup constitues an ideal system to study boundaryless 2D collective behavior with purely hydrodynamic long range interactions. Recent studies have indeed shown that quasi-spherical particles may undergo net propulsion, a feature partially understood theoretically in the particular case of infinite viscous boundary layers. We here extend the theoretical results of to any boundary layer thickness, by that meeting typical experimental conditions. In addition, we propose an explanation for the net spinning of the trapped particles, as observed in experiments.

Strong-field control and enhancement of chiral response in bi-elliptical high-order harmonic generation: an analytical model

NASA Astrophysics Data System (ADS)

Ayuso, David; Decleva, Piero; Patchkovskii, Serguei; Smirnova, Olga

2018-06-01

The generation of high-order harmonics in a medium of chiral molecules driven by intense bi-elliptical laser fields can lead to strong chiroptical response in a broad range of harmonic numbers and ellipticities (Ayuso et al 2018 J. Phys. B: At. Mol. Opt. Phys. 51 06LT01). Here we present a comprehensive analytical model that can describe the most relevant features arising in the high-order harmonic spectra of chiral molecules driven by strong bi-elliptical fields. Our model recovers the physical picture underlying chiral high-order harmonic generation (HHG) based on ultrafast chiral hole motion and identifies the rotationally invariant molecular pseudoscalars responsible for chiral dynamics. Using the chiral molecule propylene oxide as an example, we show that one can control and enhance the chiral response in bi-elliptical HHG by tailoring the driving field, in particular by tuning its frequency, intensity and ellipticity, exploiting a suppression mechanism of achiral background based on the linear Stark effect.

Solvent polarity effects on supramolecular chirality of a polyfluorene-thiophene copolymer.

PubMed

Hirahara, Takashi; Yoshizawa-Fujita, Masahiro; Takeoka, Yuko; Rikukawa, Masahiro

2018-06-01

This study demonstrates the supramolecular chirality control of a conjugated polymer via solvent polarity. We designed and synthesized a chiral polyfluorene-thiophene copolymer having two different chiral side chains at the 9-position of the fluorene unit. Chiral cyclic and alkyl ethers with different polarities were selected as the chiral side chains. The sign of the circular dichroism spectra in the visible wavelength region was affected by the solvent system, resulting from the change of supramolecular structure. The estimation of the solubility parameter revealed that the solubility difference of the side chains contributed to the change of the circular dichroism sign, which was also observed in spin-coated films prepared from good solvents having different polarities. © 2018 Wiley Periodicals, Inc.

Chiral Plasmonic Nanostructures Fabricated by Circularly Polarized Light.

PubMed

Saito, Koichiro; Tatsuma, Tetsu

2018-05-09

The chirality of materials results in a wide variety of advanced technologies including image display, data storage, light management including negative refraction, and enantioselective catalysis and sensing. Here, we introduce chirality to plasmonic nanostructures by using circularly polarized light as the sole chiral source for the first time. Gold nanocuboids as precursors on a semiconductor were irradiated with circularly polarized light to localize electric fields at specific corners of the cuboids depending on the handedness of light and deposited dielectric moieties as electron oscillation boosters by the localized electric field. Thus, plasmonic nanostructures with high chirality were developed. The present bottom-up method would allow the large-scale and cost-effective fabrication of chiral materials and further applications to functional materials and devices.

Nonlocal homogenization theory in metamaterials: Effective electromagnetic spatial dispersion and artificial chirality

NASA Astrophysics Data System (ADS)

Ciattoni, Alessandro; Rizza, Carlo

2015-05-01

We develop, from first principles, a general and compact formalism for predicting the electromagnetic response of a metamaterial with nonmagnetic inclusions in the long-wavelength limit, including spatial dispersion up to the second order. Specifically, by resorting to a suitable multiscale technique, we show that the effective medium permittivity tensor and the first- and second-order tensors describing spatial dispersion can be evaluated by averaging suitable spatially rapidly varying fields, each satisfying electrostatic-like equations within the metamaterial unit cell. For metamaterials with negligible second-order spatial dispersion, we exploit the equivalence of first-order spatial dispersion and reciprocal bianisotropic electromagnetic response to deduce a simple expression for the metamaterial chirality tensor. Such an expression allows us to systematically analyze the effect of the composite spatial symmetry properties on electromagnetic chirality. We find that even if a metamaterial is geometrically achiral, i.e., it is indistinguishable from its mirror image, it shows pseudo-chiral-omega electromagnetic chirality if the rotation needed to restore the dielectric profile after the reflection is either a 0∘ or 90∘ rotation around an axis orthogonal to the reflection plane. These two symmetric situations encompass two-dimensional and one-dimensional metamaterials with chiral response. As an example admitting full analytical description, we discuss one-dimensional metamaterials whose single chirality parameter is shown to be directly related to the metamaterial dielectric profile by quadratures.

On a chiral analog of the Einstein-de Haas effect

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zakharov, V. I., E-mail: vzakharov@itep.ru

The Einstein-de Haas effect reveals a transfer of angular momentum from microscopic constituents (electrons) to a macroscopic body, but in the case of massless fermions, one could expect the transfer of the chirality of constituents to macroscopic helical motion. For such a picture to be consistent, the macroscopic helicity is to be conserved classically, to echo the conservation of the angular momentum of a rotating body. The helicity conservation would in turn impose constraints on hydrodynamics of chiral liquids (whose constituents are massless fermions). Essentially, the chiral liquids are dissipation-free, on the classical level. Reservations and alternatives to this scenariomore » are discussed.« less

Effects of Composite Pions on the Chiral Condensate within the PNJL Model at Finite Temperature

NASA Astrophysics Data System (ADS)

Blaschke, D.; Dubinin, A.; Ebert, D.; Friesen, A. V.

2018-05-01

We investigate the effect of composite pions on the behaviour of the chiral condensate at finite temperature within the Polyakov-loop improved NJL model. To this end we treat quark-antiquark correlations in the pion channel (bound states and scattering continuum) within a Beth-Uhlenbeck approach that uses medium-dependent phase shifts. A striking medium effect is the Mott transition which occurs when the binding energy vanishes and the discrete pion bound state merges the continuum. This transition is triggered by the lowering of the continuum edge due to the chiral restoration transition. This in turn also entails a modification of the Polyakov-loop so that the SU(3) center symmetry gets broken at finite temperature and dynamical quarks (and gluons) appear in the system, taking over the role of the dominant degrees of freedom from the pions. At low temperatures our model reproduces the chiral perturbation theory result for the chiral condensate while at high temperatures the PNJL model result is recovered. The new aspect of the current work is a consistent treatment of the chiral restoration transition region within the Beth-Uhlenbeck approach on the basis of mesonic phase shifts for the treatment of the correlations.

On the effect of basic and acidic additives on the separation of the enantiomers of some basic drugs with polysaccharide-based chiral selectors and polar organic mobile phases.

PubMed

Mosiashvili, L; Chankvetadze, L; Farkas, T; Chankvetadze, B

2013-11-22

This article reports the systematic study of the effect of basic and acidic additives on HPLC separation of enantiomers of some basic chiral drugs on polysaccharide-based chiral columns under polar organic mobile-phase conditions. In contrary to generally accepted opinion that the basic additives improve the separation of enantiomers of basic compounds, the multiple scenarios were observed including the increase, decrease, disappearance and appearance of separation, as well as the reversal of the enantiomer elution order of studied basic compounds induced by the acidic additives. These effects were observed on most of the studied 6 chiral columns in 2-propanol and acetonitrile as mobile phases and diethylamine as a basic additive. As acidic additives formic acid was used systematically and acetic acid and trifluoroacetic acid were applied for comparative purposes. This study illustrates that the minor acidic additives to the mobile phase can be used as for the adjustment of separation selectivity and the enantiomer elution order of basic compounds, as well as for study of chiral recognition mechanisms with polysaccharide-based chiral stationary phases. Copyright © 2013 Elsevier B.V. All rights reserved.

Boundaries, mirror symmetry, and symplectic duality in 3d N = 4 gauge theory

DOE PAGES

Bullimore, Mathew; Dimofte, Tudor; Gaiotto, Davide; ...

2016-10-20

We introduce several families of N = (2, 2) UV boundary conditions in 3d N=4 gauge theories and study their IR images in sigma-models to the Higgs and Coulomb branches. In the presence of Omega deformations, a UV boundary condition defines a pair of modules for quantized algebras of chiral Higgs- and Coulomb-branch operators, respectively, whose structure we derive. In the case of abelian theories, we use the formalism of hyperplane arrangements to make our constructions very explicit, and construct a half-BPS interface that implements the action of 3d mirror symmetry on gauge theories and boundary conditions. Finally, by studyingmore » two-dimensional compactifications of 3d N = 4 gauge theories and their boundary conditions, we propose a physical origin for symplectic duality $-$ an equivalence of categories of modules associated to families of Higgs and Coulomb branches that has recently appeared in the mathematics literature, and generalizes classic results on Koszul duality in geometric representation theory. We make several predictions about the structure of symplectic duality, and identify Koszul duality as a special case of wall crossing.« less

Through-space transfer of chiral information mediated by a plasmonic nanomaterial

NASA Astrophysics Data System (ADS)

Ostovar Pour, Saeideh; Rocks, Louise; Faulds, Karen; Graham, Duncan; Parchaňský, Václav; Bouř, Petr; Blanch, Ewan W.

2015-07-01

The ability to detect chirality gives stereochemically attuned nanosensors the potential to revolutionize the study of biomolecular processes. Such devices may structurally characterize the mechanisms of protein-ligand binding, the intermediates of amyloidogenic diseases and the effects of phosphorylation and glycosylation. We demonstrate that single nanoparticle plasmonic reporters, or nanotags, can enable a stereochemical response to be transmitted from a chiral analyte to an achiral benzotriazole dye molecule in the vicinity of a plasmon resonance from an achiral metallic nanostructure. The transfer of chirality was verified by the measurement of mirror image surface enhanced resonance Raman optical activity spectra for the two enantiomers of both ribose and tryptophan. Computational modelling confirms these observations and reveals the novel chirality transfer mechanism responsible. This is the first report of colloidal metal nanoparticles in the form of single plasmonic substrates displaying an intrinsic chiral sensitivity once attached to a chiral molecule.

A molecular propeller effect for chiral separation and analysis

PubMed Central

Clemens, Jonathon B.; Kibar, Osman; Chachisvilis, Mirianas

2015-01-01

Enantiomers share nearly identical physical properties but have different chiral geometries, making their identification and separation difficult. Here we show that when exposed to a rotating electric field, the left- and right-handed chiral molecules rotate with the field and act as microscopic propellers; moreover, owing to their opposite handedness, they propel along the axis of field rotation in opposite directions. We introduce a new molecular parameter called hydrodynamic chirality to characterize the coupling of rotational motion of a chiral molecule into its translational motion and quantify the direction and velocity of such motion. We demonstrate >80% enrichment level of counterpart enantiomers in solution without using chiral selectors or circularly polarized light. We expect our results to have an impact on multiple applications in drug discovery, analytical and chiral chemistry, including determination of absolute configuration, as well as in influencing the understanding of artificial and natural molecular systems where rotational motion of the molecules is involved. PMID:26216219

Real-Space Mapping of the Chiral Near-Field Distributions in Spiral Antennas and Planar Metasurfaces.

PubMed

Schnell, M; Sarriugarte, P; Neuman, T; Khanikaev, A B; Shvets, G; Aizpurua, J; Hillenbrand, R

2016-01-13

Chiral antennas and metasurfaces can be designed to react differently to left- and right-handed circularly polarized light, which enables novel optical properties such as giant optical activity and negative refraction. Here, we demonstrate that the underlying chiral near-field distributions can be directly mapped with scattering-type scanning near-field optical microscopy employing circularly polarized illumination. We apply our technique to visualize, for the first time, the circular-polarization selective nanofocusing of infrared light in Archimedean spiral antennas, and explain this chiral optical effect by directional launching of traveling waves in analogy to antenna theory. Moreover, we near-field image single-layer rosette and asymmetric dipole-monopole metasurfaces and find negligible and strong chiral optical near-field contrast, respectively. Our technique paves the way for near-field characterization of optical chirality in metal nanostructures, which will be essential for the future development of chiral antennas and metasurfaces and their applications.

High-performance liquid chromatographic separations of stereoisomers of chiral basic agrochemicals with polysaccharide-based chiral columns and polar organic mobile phases.

PubMed

Matarashvili, Iza; Shvangiradze, Iamze; Chankvetadze, Lali; Sidamonidze, Shota; Takaishvili, Nino; Farkas, Tivadar; Chankvetadze, Bezhan

2015-12-01

The separation of the stereoisomers of 23 chiral basic agrochemicals was studied on six different polysaccharide-based chiral columns in high-performance liquid chromatography with various polar organic mobile phases. Along with the successful separation of analyte stereoisomers, emphasis was placed on the effect of the chiral selector and mobile phase composition on the elution order of stereoisomers. The interesting phenomenon of reversal of enantiomer/stereoisomer elution order function of the polysaccharide backbone (cellulose or amylose), type of derivative (carbamate or benzoate), nature, and position of the substituent(s) in the phenylcarbamate moiety (methyl or chloro) and the nature of the mobile phase was observed. For several of the analytes containing two chiral centers all four stereoisomers were resolved with at least one chiral selector/mobile phase combination. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A molecular propeller effect for chiral separation and analysis

NASA Astrophysics Data System (ADS)

Clemens, Jonathon B.; Kibar, Osman; Chachisvilis, Mirianas

2015-07-01

Enantiomers share nearly identical physical properties but have different chiral geometries, making their identification and separation difficult. Here we show that when exposed to a rotating electric field, the left- and right-handed chiral molecules rotate with the field and act as microscopic propellers; moreover, owing to their opposite handedness, they propel along the axis of field rotation in opposite directions. We introduce a new molecular parameter called hydrodynamic chirality to characterize the coupling of rotational motion of a chiral molecule into its translational motion and quantify the direction and velocity of such motion. We demonstrate >80% enrichment level of counterpart enantiomers in solution without using chiral selectors or circularly polarized light. We expect our results to have an impact on multiple applications in drug discovery, analytical and chiral chemistry, including determination of absolute configuration, as well as in influencing the understanding of artificial and natural molecular systems where rotational motion of the molecules is involved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koch, Volker

These lectures are an attempt to a pedagogical introduction into the elementary concepts of chiral symmetry in nuclear physics. We will also discuss some effective chiral models such as the linear and nonlinear sigma model as well as the essential ideas of chiral perturbation theory. We will present some applications to the physics of ultrarelativistic heavy ion collisionsd.

Probing the importance of the hemilabile site of bis(phosphine) monoxide ligands in the copper-catalyzed addition of diethylzinc to N-phosphinoylimines: discovery of new effective chiral ligands.

PubMed

Bonnaventure, Isabelle; Charette, André B

2008-08-15

The hemilabile ligand Me-DuPHOS(O) 2 has proven to be a successful ligand for the copper-catalyzed addition of diethylzinc to N-phosphinoylimines. The corresponding alpha-chiral amines were obtained in high yields (80-98%) and enantiomeric ratios (19.0:1 to 99.0:1 er). Furthermore, this Cu* 2 catalytic system has been shown to be effective in the addition of diethylzinc to nitroalkenes and in the reduction of beta,beta-disubstituted vinyl phenyl sulfones. This paper describes a general structure/selectivity study in which the three ligand subunits (chiral phospholane-linker-labile coordinating group (Z)) are systematically modified and tested in the copper-catalyzed addition of diethylzinc to the N-phosphinoylimine 1 derived from benzaldehyde. This study led to the discovery of a new class of effective chiral ligands that combine a chiral phospholane unit and an achiral phosphine oxide.

Chiral phases of fundamental and adjoint quarks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Natale, A. A.; Instituto de Física Teórica - UNESP Rua Dr. Bento T. Ferraz, 271, Bl.II - 01140-070, São Paulo, SP

2016-01-22

We consider a QCD chiral symmetry breaking model where the gap equation contains an effective confining propagator and a dressed gluon propagator with a dynamically generated mass. This model is able to explain the ratios between the chiral transition and deconfinement temperatures in the case of fundamental and adjoint quarks. It also predicts the recovery of the chiral symmetry for a large number of quarks (n{sub f} ≈ 11 – 13) in agreement with lattice data.

Fluid-gravity model for the chiral magnetic effect.

PubMed

Kalaydzhyan, Tigran; Kirsch, Ingo

2011-05-27

We consider the STU model as a gravity dual of a strongly coupled plasma with multiple anomalous U(1) currents. In the bulk we add additional background gauge fields to include the effects of external electric and magnetic fields on the plasma. Reducing the number of chemical potentials in the STU model to two and interpreting them as quark and chiral chemical potential, we obtain a holographic description of the chiral magnetic and chiral vortical effects (CME and CVE) in relativistic heavy-ion collisions. These effects formally appear as first-order transport coefficients in the electromagnetic current. We compute these coefficients from our model using fluid-gravity duality. We also find analogous effects in the axial-vector current. Finally, we briefly discuss a variant of our model, in which the CME/CVE is realized in the late-time dynamics of an expanding plasma. © 2011 American Physical Society

Biomarkers of Oxidative Stress in the Assessment of Enantioselective Toxicity of Chiral Pesticides.

PubMed

Ye, Xiaoqing; Liu, Ying; Li, Feixue

2017-01-01

In biological systems, the individual stereoisomers of chiral substances possess significantly different biochemical properties because the specific structure-activity relationships are required for a common site on biomolecules. In the past decade, there has been increasing concern over the enantioselective toxicity of environmental chiral pollutants, especially chiral pesticides. Different responses and activities of a pair of enantiomers of chiral pesticides were often observed. Therefore, assessment of the enantioselective toxicological properties of chiral pesticides is a prerequisite in application of single-isomer products and particularly important for environmental protection. The development of biomarkers that can predict enantioselective effects from chiral pesticides has recently been gained more and more attention. The biomarkers of oxidative stress have become a topic of significant interest for toxic assessments. In this review, we summarized current knowledge and advances in the understanding of enantiomeric oxidative processes in biological systems in response to chiral pesticides. The consistent results in two types of chiral insecticides (synthetic pyrethroids and organochlorine pesticides) showed the significant difference in cytotoxicity of enantiomers, suggesting the antioxidant enzymes are reliable biomarkers for the assessment of toxicity of chiral chemicals. Results indicate that antioxidant enzymes are sensitive and valid biomarkers to assess the oxidative damage caused by chiral herbicides. In addition, it can be inferred that the enantioselectivity of chiral herbicides on antioxidant enzymes exists in other species. Compared with insecticides and herbicides, researches about the enantioselectivity of oxidative stress caused by chiral fungicides are quite limited. Only two kinds of chiral fungicides has been used to study the enantioselectivity of oxidative stress by now. The current knowledge that enantioselective processes of oxidative damage occur in organisms or cells extends toxicological studies of environmental contamination by chiral chemicals. These studies indicate that oxidative biomarkers can be useful for monitoring enantioselective toxicity of chiral contaminates, while comparing enantiomer-induced responses in different species should be approached with caution because of differences in uptake, target sites, biotransformation and pharmacokinetics of the enantiomers.

Observation of the Zero Hall Plateau in a Quantum Anomalous Hall Insulator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feng, Yang; Feng, Xiao; Ou, Yunbo

We report experimental investigations on the quantum phase transition between the two opposite Hall plateaus of a quantum anomalous Hall insulator. We observe a well-defined plateau with zero Hall conductivity over a range of magnetic field around coercivity when the magnetization reverses. The features of the zero Hall plateau are shown to be closely related to that of the quantum anomalous Hall effect, but its temperature evolution exhibits a significant difference from the network model for a conventional quantum Hall plateau transition. We propose that the chiral edge states residing at the magnetic domain boundaries, which are unique to amore » quantum anomalous Hall insulator, are responsible for the novel features of the zero Hall plateau.« less

Corolla chirality does not contribute to directed pollen movement in Hypericum perforatum (Hypericaceae): mirror image pinwheel flowers function as radially symmetric flowers in pollination.

PubMed

Diller, Carolina; Fenster, Charles B

2016-07-01

Corolla chirality, the pinwheel arrangement of petals within a flower, is found throughout the core eudicots. In 15 families, different chiral type flowers (i.e., right or left rotated corolla) exist on the same plant, and this condition is referred to as unfixed/enantiomorphic corolla chirality. There are no investigations on the significance of unfixed floral chirality on directed pollen movement even though analogous mirror image floral designs, for example, enantiostyly, has evolved in response to selection to direct pollinator and pollen movement. Here, we examine the role of corolla chirality on directing pollen transfer, pollinator behavior, and its potential influence on disassortative mating. We quantified pollen transfer and pollinator behavior and movement for both right and left rotated flowers in two populations of Hypericum perforatum. In addition, we quantified the number of right and left rotated flowers at the individual level. Pollinators were indifferent to corolla chirality resulting in no difference in pollen deposition between right and left flowers. Corolla chirality had no effect on pollinator and pollen movement between and within chiral morphs. Unlike other mirror image floral designs, corolla chirality appears to play no role in promoting disassortative mating in this species.

Staggered chiral perturbation theory in the two-flavor case

DOE Office of Scientific and Technical Information (OSTI.GOV)

Du Xining

2010-07-01

I study two-flavor staggered chiral perturbation theory in the light pseudoscalar sector. The pion mass and decay constant are calculated through next-to-leading order in the partially-quenched case. In the limit where the strange quark mass is large compared to the light quark masses and the taste splittings, I show that the SU(2) staggered chiral theory emerges from the SU(3) staggered chiral theory, as expected. Explicit relations between SU(2) and SU(3) low energy constants and taste-violating parameters are given. The results are useful for SU(2) chiral fits to asqtad data and allow one to incorporate effects from varying strange quark masses.

Effective interactions between inclusions in an active bath

NASA Astrophysics Data System (ADS)

Zaeifi Yamchi, Mahdi; Naji, Ali

2017-11-01

We study effective two- and three-body interactions between non-active colloidal inclusions in an active bath of chiral or non-chiral particles, using Brownian dynamics simulations within a standard, two-dimensional model of disk-shaped inclusions and active particles. In a non-chiral active bath, we first corroborate previous findings on effective two-body repulsion mediated between the inclusions by elucidating the detailed non-monotonic features of the two-body force profiles, including a primary maximum and a secondary hump at larger separations that was not previously reported. We then show that these features arise directly from the formation, and sequential overlaps, of circular layers (or "rings") of active particles around the inclusions, as the latter are brought to small surface separations. These rings extend to radial distances of a few active-particle radii from the surface of inclusions, giving the hard-core inclusions relatively thick, soft, repulsive "shoulders," whose multiple overlaps then enable significant (non-pairwise) three-body forces in both non-chiral and chiral active baths. The resulting three-body forces can even exceed the two-body forces in magnitude and display distinct repulsive and attractive regimes at intermediate to large self-propulsion strengths. In a chiral active bath, we show that, while active particles still tend to accumulate at the immediate vicinity of the inclusions, they exhibit strong depletion from the intervening region between the inclusions and partial depletion from relatively thick, circular zones further away from the inclusions. In this case, the effective, predominantly repulsive interactions between the inclusions turn to active, chirality-induced, depletion-type attractions, acting over an extended range of separations.

Application of classical models of chirality to optical rectification

NASA Astrophysics Data System (ADS)

Wang, Xiao-Ou; Gong, Li-Jing; Li, Chun-Fei

2008-08-01

Classical models of chirality are used to investigate the optical rectification effect in chiral molecular media. Calculation of the zero frequency first hyperpolarizabilities of chiral molecules with different structures is performed and applied to the derivation of a dc electric-dipole polarization. The expression of second-order nonlinear static-electric-dipole susceptibilities is obtained by theoretical derivation in the isotropic chiral thin films. The microscopic mechanism producing optical rectification is analyzed in view of this calculation. We find that optical rectification is derived from interaction between the electric field gradient (spatial dispersion) and chiral molecules in optically active liquids and solution by our calculation, which is consistent with the result given by Woźniak and Wagnière [Opt. Commun. 114, 131 (1995)]: The optical rectification depends on the fourth-order electric-dipole susceptibilities.

Complexity growth in massive gravity theories, the effects of chirality, and more

NASA Astrophysics Data System (ADS)

Ghodrati, Mahdis

2017-11-01

To study the effect of parity violation on the rate of complexity growth, by using "complexity=action " conjecture, we find the complexity growth rates in different solutions of the chiral theory of topologically massive gravity (TMG) and parity-preserving theory of new massive gravity (NMG). Using the results, one can see that decreasing the parameter μ , which increases the effect of the Chern-Simons term and increases chirality, would increase the rate of growth of complexity. Also one can observe a stronger correlation between complexity growth and temperature rather than complexity growth and entropy. At the end we comment on the possible meaning of the deforming term of chiral Liouville action for the rate of complexity growth of warped conformal field theories in the tensor network renormalization picture.

Anomalous transport and generalized axial charge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirilin, Vladimir P.; Sadofyev, Andrey V.

For this article, we continue studying the modification of the axial charge in chiral media by macroscopic helicities. Recently it was shown that magnetic reconnections result in a persistent current of zero mode along flux tubes. Here we argue that in general a change in the helical part of the generalized axial charge results in the same phenomenon. Thus one may say that there is a novel realization of chiral effects requiring no initial chiral asymmetry. The transfer of flow helicity to zero modes is analyzed in a toy model based on a vortex reconnection in a chiral superfluid. Then,more » we discuss the balance between the two competing processes effect of reconnections and the chiral instability on the example of magnetic helicity. We argue that in the general case there is a possibility for the distribution of the axial charge between the magnetic and fermionic forms at the end of the instability.« less

The charmonium dissociation in an ''anomalous wind''

DOE PAGES

Sadofyev, Andrey V.; Yin, Yi

2016-01-11

We study the charmonium dissociation in a strongly coupled chiral plasma in the presence of magnetic field and axial charge imbalance. This type of plasma carries "anomalous flow" induced by the chiral anomaly and exhibits novel transport phenomena such as chiral magnetic effect. We found that the "anomalous flow" would modify the charmonium color screening length by using the gauge/gravity correspondence. We derive an analytical expression quantifying the "anomalous flow" experienced by a charmonium for a large class of chiral plasma with a gravity dual. We elaborate on the similarity and it qualitative difference between anomalous effects on the charmoniummore » color screening length which are model-dependent and those on the heavy quark drag force which are fixed by the second law of thermodynamics. As a result, we speculate on the possible charmonium dissociation induced by the chiral anomaly in heavy ion collisions.« less

Anomalous transport and generalized axial charge

DOE PAGES

Kirilin, Vladimir P.; Sadofyev, Andrey V.

2017-07-25

For this article, we continue studying the modification of the axial charge in chiral media by macroscopic helicities. Recently it was shown that magnetic reconnections result in a persistent current of zero mode along flux tubes. Here we argue that in general a change in the helical part of the generalized axial charge results in the same phenomenon. Thus one may say that there is a novel realization of chiral effects requiring no initial chiral asymmetry. The transfer of flow helicity to zero modes is analyzed in a toy model based on a vortex reconnection in a chiral superfluid. Then,more » we discuss the balance between the two competing processes effect of reconnections and the chiral instability on the example of magnetic helicity. We argue that in the general case there is a possibility for the distribution of the axial charge between the magnetic and fermionic forms at the end of the instability.« less

Emergence of Chiral Phases in Active Torque Dipole Systems

NASA Astrophysics Data System (ADS)

Fialho, Ana; Tjhung, Elsen; Cates, Michael; Marenduzzo, Davide

The common description of active particles as active force dipoles fails to take into account that active processes in biological systems often exhibit chiral asymmetries, generating active chiral processes and torque dipoles. Examples of such systems include cytoskeleton filaments which interact with motor proteins and beating cilia and flagella. In particular, the generation of active torques by the actomyosin cytoskeleton has been linked to the break of chiral symmetry at a cellular level. This phenomenon could constitute the primary determinant for the break of left-right symmetry in many living organisms, e.g. the position of the human heart within the human body. In order to account for the effects of chirality, we consider active torque dipoles which generate a chiral active stress. We characterize quasi-1D and 2D systems of torque dipoles, using a combination of linear stability analysis and numerical simulations (Lattice Boltzmann). Our results show that activity drives a spontaneous breaking of chiral symmetry, leading to the self-assembly of a chiral phase, in the absence of any thermodynamic interactions favoring cholesteric ordering. At high values of activity, we also observe labyrinthine patterns where the activity-induced chiral ordering is highly frustrated.

Fluorescence Turn-on Enantioselective Recognition of both Chiral Acidic Compounds and α-Amino Acids by a Chiral Tetraphenylethylene Macrocycle Amine.

PubMed

Feng, Hai-Tao; Zhang, Xing; Zheng, Yan-Song

2015-08-21

New chiral tetraphenylethylene (TPE) macrocycles bearing optically pure amine groups were synthesized and found to have a discriminating ability between the two enantiomers of not only chiral acidic compounds but also α-amino acids by enantioselective aggregation and aggregation-induced emission (AIE) effects. NMR spectra, including 2D-NOESY, disclosed that the host-guest interaction of the macrocycle receptor played a key role in addition to the acid-base interactions.

ENANTIOMER-SPECIFIC FATE AND EFFECTS OF MODERN CHIRAL PESTICIDES

EPA Science Inventory

This slide presentation presents enantiomer-specific fate and effects of modern chiral pesticides. The research areas presented were analytical separation of enantiomers; environmental occurrence of enantiomers; transformation rates and enantioselectivity; bioaccumulation; and e...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, C. D.; Schmidt, S. M.; Physics

Continuum strong QCD is the application of models and continuum quantum field theory to the study of phenomena in hadronic physics, which includes; e.g., the spectrum of QCD bound states and their interactions; and the transition to, and properties of, a quark gluon plasma. We provide a contemporary perspective, couched primarily in terms of the Dyson-Schwinger equations but also making comparisons with other approaches and models. Our discourse provides a practitioners' guide to features of the Dyson-Schwinger equations [such as confinement and dynamical chiral symmetry breaking] and canvasses phenomenological applications to light meson and baryon properties in cold, sparse QCD.more » These provide the foundation for an extension to hot, dense QCD, which is probed via the introduction of the intensive thermodynamic variables: chemical potential and temperature. We describe order parameters whose evolution signals deconfinement and chiral symmetry restoration, and chronicle their use in demarcating the quark gluon plasma phase boundary and characterizing the plasma's properties. Hadron traits change in an equilibrated plasma. We exemplify this and discuss putative signals of the effects. Finally, since plasma formation is not an equilibrium process, we discuss recent developments in kinetic theory and its application to describing the evolution from a relativistic heavy ion collision to an equilibrated quark gluon plasma.« less

Chiral Magnetic Effect and Anomalous Transport from Real-Time Lattice Simulations

DOE PAGES

Müller, Niklas; Schlichting, Sören; Sharma, Sayantan

2016-09-30

Here, we present a first-principles study of anomaly induced transport phenomena by performing real-time lattice simulations with dynamical fermions coupled simultaneously to non-Abelian S U ( N c ) and Abelian U ( 1 ) gauge fields. By investigating the behavior of vector and axial currents during a sphaleron transition in the presence of an external magnetic field, we demonstrate how the interplay of the chiral magnetic and chiral separation effect leads to the formation of a propagating wave. Furthermore, we analyze the dependence of the magnitude of the induced vector current and the propagation of the wave on themore » amount of explicit chiral symmetry breaking due to finite quark masses.« less

Hall viscosity of a chiral two-orbital superconductor at finite temperatures

NASA Astrophysics Data System (ADS)

Yazdani-Hamid, Meghdad; Shahzamanian, Mohammad Ali

2018-06-01

The Hall viscosity known as the anti-symmetric part of the viscosity fourth-rank tensor. Such dissipationless response which appears for systems with broken time reversal symmetry. We calculate this non-dissipative quantity for a chiral two-orbital superconductor placed in a viscoelastic magnetic field using the linear response theory and apply our calculations to the putative multiband chiral superconductor Sr2RuO4. The chirality origin of a multiband superconductor arises from the interorbital coupling of the superconducting state. This feature leads to the robustness of the Hall viscosity against temperature and impurity effects. We study the temperature effect on the Hall viscosity at the one-loop approximation.

Magnetotransport in Dirac metals: Chiral magnetic effect and quantum oscillations

DOE PAGES

Monteiro, Gustavo M.; Abanov, Alexander G.; Kharzeev, Dmitri E.

2015-10-08

Dirac metals are characterized by the linear dispersion of fermionic quasiparticles, with the Dirac point hidden inside a Fermi surface. We study the magnetotransport in these materials using chiral kinetic theory to describe within the same framework both the negative magnetoresistance caused by the chiral magnetic effect and quantum oscillations in the magnetoresistance due to the existence of the Fermi surface. Lastly, we discuss the relevance of obtained results to recent measurements on Cd 3As 2.

Spin and chirality effects in antler-topology processes at high energy $${e^+e^-}$$ colliders

DOE PAGES

Choi, S. Y.; Christensen, N. D.; Salmon, D.; ...

2015-10-01

We perform a model-independent investigation of spin and chirality correlation effects in the antler-topology processes e +e -→P +P -→(ℓ+D0)(ℓ-D¯0) at high-energy e +e - colliders with polarized beams. Generally the production process e +e -→P +P - can occur not only through the s-channel exchange of vector bosons, V0 , including the neutral Standard Model (SM) gauge bosons, γ and Z, but also through the s- and t-channel exchanges of new neutral states, S0 and T0 , and the u-channel exchange of new doubly charged states, U-- . The general set of (non-chiral) three-point couplings of the new particlesmore » and leptons allowed in a renormalizable quantum field theory is considered. The general spin and chirality analysis is based on the threshold behavior of the excitation curves for P +P - pair production in e +e - collisions with longitudinal- and transverse-polarized beams, the angular distributions in the production process and also the production-decay angular correlations. In the first step, we present the observables in the helicity formalism. Subsequently, we show how a set of observables can be designed for determining the spins and chiral structures of the new particles without any model assumptions. Finally, taking into account a typical set of approximately chiral invariant scenarios, we demonstrate how the spin and chirality effects can be probed experimentally at a high-energy e +e - collider.« less

Spin and chirality effects in antler-topology processes at high energy $$\\varvec{e^+e^-}$$ e + e - colliders

DOE PAGES

Choi, S. Y.; Christensen, N. D.; Salmon, D.; ...

2015-10-01

We perform a model-independent investigation of spin and chirality correlation effects in the antler-topology processes e+e−→P+P−→(ℓ+D0)(ℓ−D¯0) at high-energy e+e− colliders with polarized beams. Generally the production process e+e−→P+P− can occur not only through the s-channel exchange of vector bosons, V0 , including the neutral Standard Model (SM) gauge bosons, γ and Z, but also through the s- and t-channel exchanges of new neutral states, S0 and T0 , and the u-channel exchange of new doubly charged states, U−− . The general set of (non-chiral) three-point couplings of the new particles and leptons allowed in a renormalizable quantum field theory ismore » considered. The general spin and chirality analysis is based on the threshold behavior of the excitation curves for P+P− pair production in e+e− collisions with longitudinal- and transverse-polarized beams, the angular distributions in the production process and also the production-decay angular correlations. In the first step, we present the observables in the helicity formalism. Subsequently, we show how a set of observables can be designed for determining the spins and chiral structures of the new particles without any model assumptions. Finally, taking into account a typical set of approximately chiral invariant scenarios, we demonstrate how the spin and chirality effects can be probed experimentally at a high-energy e+e− collider.« less

Spin and chirality effects in antler-topology processes at high energy $${e^+e^-}$$ colliders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, S. Y.; Christensen, N. D.; Salmon, D.

We perform a model-independent investigation of spin and chirality correlation effects in the antler-topology processes e +e -→P +P -→(ℓ+D0)(ℓ-D¯0) at high-energy e +e - colliders with polarized beams. Generally the production process e +e -→P +P - can occur not only through the s-channel exchange of vector bosons, V0 , including the neutral Standard Model (SM) gauge bosons, γ and Z, but also through the s- and t-channel exchanges of new neutral states, S0 and T0 , and the u-channel exchange of new doubly charged states, U-- . The general set of (non-chiral) three-point couplings of the new particlesmore » and leptons allowed in a renormalizable quantum field theory is considered. The general spin and chirality analysis is based on the threshold behavior of the excitation curves for P +P - pair production in e +e - collisions with longitudinal- and transverse-polarized beams, the angular distributions in the production process and also the production-decay angular correlations. In the first step, we present the observables in the helicity formalism. Subsequently, we show how a set of observables can be designed for determining the spins and chiral structures of the new particles without any model assumptions. Finally, taking into account a typical set of approximately chiral invariant scenarios, we demonstrate how the spin and chirality effects can be probed experimentally at a high-energy e +e - collider.« less

Paraxial propagation of the first-order chirped Airy vortex beams in a chiral medium.

PubMed

Xie, Jintao; Zhang, Jianbin; Ye, Junran; Liu, Haowei; Liang, Zhuoying; Long, Shangjie; Zhou, Kangzhu; Deng, Dongmei

2018-03-05

We introduce the propagation of the first-order chirped Airy vortex beams (FCAiV) in a chiral medium analytically. Results show that the FCAiV beams split into the left circularly polarized vortex (LCPV) beams and the right circularly polarized vortex (RCPV) beams, which have totally different propagation trajectories in the chiral medium. In this paper, we investigate the effects of the first-order chirped parameter β, the chiral parameter γ and the optical vortex on the propagation process of the FCAiV beams. It is shown that the propagation trajectory of the FCAiV beams declines with the chirped parameter increasing. Besides, the increase of the chiral parameter acting on the LCPV beams makes the relative position between the main lobe and the optical vortex further while the effect on the RCPV beams is the opposite. Furthermore, the relative position between the main lobe and the optical vortex contributes to the position of the intensity focusing. Meanwhile, with the chiral parameter increasing, the maximum gradient and scattering forces of the LCPV beams decrease but those of the RCPV beams will increase during the propagation. It is significant that we can control the propagation trajectory, the intensity focusing position and the radiation forces of the FCAiV beams by varying the chirped parameter and the chiral parameter.

Chirality plays critical roles in enhancing the aqueous solubility of nocathiacin I by block copolymer micelles.

PubMed

Feng, Kun; Wang, Shuzhen; Ma, Hairong; Chen, Yijun

2013-01-01

Although drug solubilization by block copolymer micelles has been extensively studied, the rationale behind the choice of appropriate block copolymer micelles for various poorly water-soluble drugs has been of relatively less concern. The objective of this study was to use methoxy-poly(ethylene glycol)-polylactate micelles (MPEG-PLA) to solubilize glycosylated antibiotic nocathiacin I and to compare the effects of chirality on the enhancement of aqueous solubility. Nocathiacin I-loaded MPEG-PLA micelles with opposite optical property in PLA were synthesized and characterized. The drug release profile, micelle stability and preliminary safety properties of MPEG-PLA micelles were evaluated. Meanwhile, three other poorly water-soluble chiral compound-loaded micelles were also prepared and compared.  The aqueous solubility of nocathiacin I was greatly enhanced by both L- and D-copolymers, with the degree of enhancement appearing to depend on the chirality of the copolymers. Comparison of different chiral compounds confirmed the trend that aqueous solubility of chiral compounds can be more effectively enhanced by block copolymer micelles with specific stereochemical configuration. The present study introduced chiral concept on the selection and preparation of block copolymer micelles for the enhancement of aqueous solubility of poorly water-soluble drugs. © 2012 The Authors. JPP © 2012 Royal Pharmaceutical Society.

Inversion of Supramolecular Chirality by Sonication-Induced Organogelation

PubMed Central

Maity, Sibaprasad; Das, Priyadip; Reches, Meital

2015-01-01

Natural helical structures have inspired the formation of well-ordered peptide-based chiral nanostructures in vitro. These structures have drawn much attention owing to their diverse applications in the area of asymmetric catalysts, chiral photonic materials, and nanoplasmonics. The self-assembly of two enantiomeric fluorinated aromatic dipeptides into ordered chiral fibrillar nanostructures upon sonication is described. These fibrils form organogels. Our results clearly indicate that fluorine-fluorine interactions play an important role in self-assembly. Circular dichroism analysis revealed that both peptides (peptides 1 and 2), containing two fluorines, depicted opposite cotton effects in their monomeric form compared with their aggregated form. This shows that supramolecular chirality inversion took place during the stimuli-responsive self-aggregation process. Conversely, peptide 3, containing one fluorine, did not exhibit chirality inversion in sonication-induced organogelation. Therefore, our results clearly indicate that fluorination plays an important role in the organogelation process of these aromatic dipeptides. Our findings may have broad implications regarding the design of chiral nanostructures for possible applications such as chiroptical switches, asymmetric catalysis, and chiral recognitions. PMID:26553508

Chirality Transfer in Gold(I)-Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study.

PubMed

Barker, Graeme; Johnson, David G; Young, Paul C; Macgregor, Stuart A; Lee, Ai-Lan

2015-09-21

Gold(I)-catalysed direct allylic etherifications have been successfully carried out with chirality transfer to yield enantioenriched, γ-substituted secondary allylic ethers. Our investigations include a full substrate-scope screen to ascertain substituent effects on the regioselectivity, stereoselectivity and efficiency of chirality transfer, as well as control experiments to elucidate the mechanistic subtleties of the chirality-transfer process. Crucially, addition of molecular sieves was found to be necessary to ensure efficient and general chirality transfer. Computational studies suggest that the efficiency of chirality transfer is linked to the aggregation of the alcohol nucleophile around the reactive π-bound Au-allylic ether complex. With a single alcohol nucleophile, a high degree of chirality transfer is predicted. However, if three alcohols are present, alternative proton transfer chain mechanisms that erode the efficiency of chirality transfer become competitive. © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Minimally doubled fermions and spontaneous chiral symmetry breaking

NASA Astrophysics Data System (ADS)

Osmanaj (Zeqirllari), Rudina; Hyka (Xhako), Dafina

2018-03-01

Chiral symmetry breaking in massless QCD is a very important feature in the current understanding of low energy physics. Low - lying Dirac modes are suitable to help us understand the spontaneous chiral symmetry breaking, since the formation of a non zero chiral condensate is an effect of their accumulation near zero. The Banks - Casher relation links the spectral density of the Dirac operator to the condensate with an identity that can be read in both directions. In this work we propose a spectral method to achieve a reliable determination of the density of eigenvalues of Dirac operator near zero using the Gauss - Lanczos quadrature. In order to understand better the dynamical chiral symmetry breaking and use the method we propose, we have chosen to work with minimally doubled fermions. These kind of fermions have been proposed as a strictly local discretization of the QCD fermions action, which preserves chiral symmetry at finite cut-off. Being chiral fermions, is easier to work with them and their low - lying Dirac modes and to understand the dynamical spontaneous chiral symmetry breaking.

Chiral separation of β-blockers by MEEKC using neutral microemulsion: Analysis of separation mechanism and further elucidation of resolution equation.

PubMed

Hu, Shao-Qiang; Lü, Wen-Juan; Ma, Yan-Hua; Hu, Qin; Dong, Li-Jun; Chen, Xing-Guo

2013-01-01

Based on the investigation of the effect of microemulsion charge on the chiral separation, a new chiral separation method with MEEKC employing neutral microemulsion was established. The method used a microemulsion containing 3.0% (w/v) neutral surfactant Tween 20 and 0.8% (w/v, 30 mM) dibutyl l-tartrate in 40 mM sodium tetraborate buffer to separate the enantiomers of β-blockers. The effect of major parameters on the chiral separation was investigated. The applied voltage had little effect on the resolution, but the chiral separation could be improved by suppressing the EOF. Nine racemic β-blockers obtained relatively good enantioseparation after appropriate concentrations of tetradecyl trimethyl ammonium bromide were added into the microemulsion to suppress the EOF. These results were explained based on the analysis of the separation mechanism of the method and deduced separation equations. The resolution equation of the method was further elucidated. It was found that the fourth term in the resolution equation, an additional term compared to the conventional resolution equation for column chromatography, represents the ratio of the relative movement distance between the analyte and microemulsion droplets relative to the effective capillary length. It can be regarded as a correction for the effective capillary length. These findings are significant for the development of the theory of MEEKC and the development of new chiral MEEKC method. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chiral magnetic and vortical effects in high-energy nuclear collisions—A status report

DOE PAGES

Kharzeev, D. E.; Liao, J.; Voloshin, S. A.; ...

2016-05-01

Here, the interplay of quantum anomalies with magnetic field and vorticity results in a variety of novel non-dissipative transport phenomena in systems with chiral fermions, including the quark–gluon plasma. Among them is the Chiral Magnetic Effect (CME)—the generation of electric current along an external magnetic field induced by chirality imbalance. Because the chirality imbalance is related to the global topology of gauge fields, the CME current is topologically protected and hence non-dissipative even in the presence of strong interactions. As a result, the CME and related quantum phenomena affect the hydrodynamical and transport behavior of strongly coupled quark–gluon plasma, andmore » can be studied in relativistic heavy ion collisions where strong magnetic fields are created by the colliding ions. Evidence for the CME and related phenomena has been reported by the STAR Collaboration at Relativistic Heavy Ion Collider at BNL, and by the ALICE Collaboration at the Large Hadron Collider at CERN. The goal of the present review is to provide an elementary introduction into the physics of anomalous chiral effects, to describe the current status of experimental studies in heavy ion physics, and to outline the future work, both in experiment and theory, needed to eliminate the existing uncertainties in the interpretation of the data.« less

On the chiral magnetic effect in Weyl superfluid 3He-A

NASA Astrophysics Data System (ADS)

Volovik, G. E.

2017-01-01

In the theory of the chiral anomaly in relativistic quantum field theories (RQFTs), some results depend on a regularization scheme at ultraviolet. In the chiral superfluid 3He-A, which contains two Weyl points and also experiences the effects of chiral anomaly, the "trans-Planckian" physics is known and the results can be obtained without regularization. We discuss this on example of the chiral magnetic effect (CME), which has been observed in 3He-A in the 1990s [1]. There are two forms of the contribution of the CME to the Chern-Simons term in free energy, perturbative and non-perturbative. The perturbative term comes from the fermions living in the vicinity of the Weyl point, where the fermions are "relativistic" and obey the Weyl equation. The non-perturbative term originates from the deep vacuum, being determined by the separation of the two Weyl points in momentum space. Both terms are obtained using the Adler-Bell-Jackiw equation for chiral anomaly, and both agree with the results of the microscopic calculations in the "trans-Planckian" region. Existence of the two nonequivalent forms of the Chern-Simons term demonstrates that the results obtained within the RQFT depend on the specific properties of the underlying quantum vacuum and may reflect different physical phenomena in the same vacuum.

Characteristics of chiral anomaly in view of various applications

NASA Astrophysics Data System (ADS)

Fujikawa, Kazuo

2018-01-01

In view of the recent applications of chiral anomaly to various fields beyond particle physics, we discuss some basic aspects of chiral anomaly which may help deepen our understanding of chiral anomaly in particle physics also. It is first shown that Berry's phase (and its generalization) for the Weyl model H =vFσ →.p →(t ) assumes a monopole form at the exact adiabatic limit but deviates from it off the adiabatic limit and vanishes in the high frequency limit of the Fourier transform of p →(t ) for bounded |p →(t )|. An effective action, which is consistent with the nonadiabatic limit of Berry's phase, combined with the Bjorken-Johnson-Low prescription, gives normal equal-time space-time commutators and no chiral anomaly. In contrast, an effective action with a monopole at the origin of the momentum space, which describes Berry's phase in the precise adiabatic limit but fails off the adiabatic limit, gives anomalous space-time commutators and a covariant anomaly to the gauge current. We regard this anomaly as an artifact of the postulated monopole and not a consequence of Berry's phase. As for the recent application of the chiral anomaly to the description of effective Weyl fermions in condensed matter and nuclear physics, which is closely related to the formulation of lattice chiral fermions, we point out that the chiral anomaly for each species doubler separately vanishes for a finite lattice spacing, contrary to the common assumption. Instead, a general form of pair creation associated with the spectral flow for the Dirac sea with finite depth takes place. This view is supported by the Ginsparg-Wilson fermion, which defines a single Weyl fermion without doublers on the lattice and gives a well-defined index (anomaly) even for a finite lattice spacing. A different use of anomaly in analogy to the partially conserved axial-vector current is also mentioned and could lead to an effect without fermion number nonconservation.

Natural terpene derivatives as new structural task-specific ionic liquids to enhance the enantiorecognition of acidic enantiomers on teicoplanin-based stationary phase by high-performance liquid chromatography.

PubMed

Flieger, Jolanta; Feder-Kubis, Joanna; Tatarczak-Michalewska, Małgorzata; Płazińska, Anita; Madejska, Anna; Swatko-Ossor, Marta

2017-06-01

We present the specific cooperative effect of a semisynthetic glycopeptide antibiotic teicoplanin and chiral ionic liquids containing the (1R,2S,5R)-(-)-menthol moiety on the chiral recognition of enantiomers of mandelic acid, vanilmandelic acid, and phenyllactic acid. Experiments were performed chromatographically on an Astec Chirobiotic T chiral stationary phase applying the mobile phase with the addition of the chiral ionic liquids. The stereoselective binding of enantiomers to teicoplanin in presence of new chiral ionic liquids were evaluated applying thermodynamic measurements and the docking simulations. Both the experimental and theoretical methods revealed that the chiral recognition of enantiomers in the presence of new chiral ionic liquids was enthalpy driven. The changes of the teicoplanin conformation occurring upon binding of the chiral ionic liquids are responsible for the differences in the standard changes in Gibbs energy (ΔG 0 ) values obtained for complexes formed by the R and S enantiomers and teicoplanin. Docking simulations revealed the steric adjustment between the chiral ionic liquids cyclohexane ring (chair conformation) and the β-d-glucosamine ring of teicoplanin and additionally hydrophobic interactions between the decanoic aliphatic chain of teicoplanin and the alkyl group of the tested salts. The obtained terpene derivatives can be considered as "structural task-specific ionic liquids" responsible for enhancing the chiral resolution in synergistic systems with two chiral selectors. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Measuring the electromagnetic chirality of 2D arrays under normal illumination.

PubMed

Garcia-Santiago, X; Burger, S; Rockstuhl, C; Fernandez-Corbaton, I

2017-10-15

We present an electromagnetic chirality measure for 2D arrays of subwavelength periodicities under normal illumination. The calculation of the measure uses only the complex reflection and transmission coefficients from the array. The measure allows the ordering of arrays according to their electromagnetic chirality, which further allows a quantitative comparison of different design strategies. The measure is upper bounded, and the extreme properties of objects with high values of electromagnetic chirality make them useful in both near- and far-field applications. We analyze the consequences that different possible symmetries of the array have on its electromagnetic chirality. We use the measure to study four different arrays. The results indicate the suitability of helices for building arrays of high electromagnetic chirality, and the low effectiveness of a substrate for breaking the transverse mirror symmetry.

Observation of chiral phonons.

PubMed

Zhu, Hanyu; Yi, Jun; Li, Ming-Yang; Xiao, Jun; Zhang, Lifa; Yang, Chih-Wen; Kaindl, Robert A; Li, Lain-Jong; Wang, Yuan; Zhang, Xiang

2018-02-02

Chirality reveals symmetry breaking of the fundamental interaction of elementary particles. In condensed matter, for example, the chirality of electrons governs many unconventional transport phenomena such as the quantum Hall effect. Here we show that phonons can exhibit intrinsic chirality in monolayer tungsten diselenide. The broken inversion symmetry of the lattice lifts the degeneracy of clockwise and counterclockwise phonon modes at the corners of the Brillouin zone. We identified the phonons by the intervalley transfer of holes through hole-phonon interactions during the indirect infrared absorption, and we confirmed their chirality by the infrared circular dichroism arising from pseudoangular momentum conservation. The chiral phonons are important for electron-phonon coupling in solids, phonon-driven topological states, and energy-efficient information processing. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Chiral Drug Analysis in Forensic Chemistry: An Overview.

PubMed

Ribeiro, Cláudia; Santos, Cristiana; Gonçalves, Valter; Ramos, Ana; Afonso, Carlos; Tiritan, Maria Elizabeth

2018-01-28

Many substances of forensic interest are chiral and available either as racemates or pure enantiomers. Application of chiral analysis in biological samples can be useful for the determination of legal or illicit drugs consumption or interpretation of unexpected toxicological effects. Chiral substances can also be found in environmental samples and revealed to be useful for determination of community drug usage (sewage epidemiology), identification of illicit drug manufacturing locations, illegal discharge of sewage and in environmental risk assessment. Thus, the purpose of this paper is to provide an overview of the application of chiral analysis in biological and environmental samples and their relevance in the forensic field. Most frequently analytical methods used to quantify the enantiomers are liquid and gas chromatography using both indirect, with enantiomerically pure derivatizing reagents, and direct methods recurring to chiral stationary phases.

Chiral resolution of spin angular momentum in linearly polarized and unpolarized light

PubMed Central

Hernández, R. J.; Mazzulla, A.; Provenzano, C.; Pagliusi, P.; Cipparrone, G.

2015-01-01

Linearly polarized (LP) and unpolarized (UP) light are racemic entities since they can be described as superposition of opposite circularly polarized (CP) components of equal amplitude. As a consequence they do not carry spin angular momentum. Chiral resolution of a racemate, i.e. separation of their chiral components, is usually performed via asymmetric interaction with a chiral entity. In this paper we provide an experimental evidence of the chiral resolution of linearly polarized and unpolarized Gaussian beams through the transfer of spin angular momentum to chiral microparticles. Due to the interplay between linear and angular momentum exchange, basic manipulation tasks, as trapping, spinning or orbiting of micro-objects, can be performed by light with zero helicity. The results might broaden the perspectives for development of miniaturized and cost-effective devices. PMID:26585284

Self-organized internal architectures of chiral micro-particles

NASA Astrophysics Data System (ADS)

Provenzano, Clementina; Mazzulla, Alfredo; Pagliusi, Pasquale; De Santo, Maria P.; Desiderio, Giovanni; Perrotta, Ida; Cipparrone, Gabriella

2014-02-01

The internal architecture of polymeric self-assembled chiral micro-particles is studied by exploring the effect of the chirality, of the particle sizes, and of the interface/surface properties in the ordering of the helicoidal planes. The experimental investigations, performed by means of different microscopy techniques, show that the polymeric beads, resulting from light induced polymerization of cholesteric liquid crystal droplets, preserve both the spherical shape and the internal self-organized structures. The method used to create the micro-particles with controlled internal chiral architectures presents great flexibility providing several advantages connected to the acquired optical and photonics capabilities and allowing to envisage novel strategies for the development of chiral colloidal systems and materials.

Electromagnetic wave propagation through a dielectric-chiral interface and through a chiral slab

NASA Technical Reports Server (NTRS)

Bassiri, S.; Papas, C. H.; Engheta, N.

1988-01-01

The reflection from and transmission through a semiinfinite chiral medium are analyzed by obtaining the Fresnel equations in terms of parallel- and perpendicular-polarized modes, and a comparison is made with results reported previously. The chiral medium is described electromagnetically by the constitutive relations D = (epsilon)E+i(gamma)B and H = i(gamma)E+(1/mu)B. The constants epsilon, mu and gamma are real and have values that are fixed by the size, the shape, and the spatial distribution of the elements that collectively compose the medium. The conditions are obtained for the total internal reflection of the incident wave from the interface and for the existence of the Brewster angle. The effects of the chirality on the polarization and the intensity of the reflected wave from the chiral half-space are discussed and illustrated by using the Stokes parameters. The propagation of electromagnetic wave through an infinite slab of chiral medium is formulated for oblique incidence and solved analytically for the case of normal incidence.

Complex Langevin simulation of chiral symmetry restoration at finite baryonic density

NASA Astrophysics Data System (ADS)

Ilgenfritz, Ernst-Michael

1986-12-01

A recently proposed effective SU(3) spin model with chiral order parameter is studied by means of the complex Langevin equation. A first-order chiral symmetry restoring and deconfining transition is observed at sufficiently low temperature at finite baryonic density. Permanent address: Sektion Physik, Karl-Marx Universität, DDR-7010 Leipzig, German Democratic Republic.

Dissymmetry effects on the laser spectroscopy of supersonically expanded rare gas/chiral arene heteroclusters.

PubMed

Filippi, Antonello; Giardini, Anna; Marcantoni, Enrico; Paladini, Alessandra; Piccirillo, Susanna; Renzi, Gabriele; Rondino, Flaminia; Roselli, Graziella; Satta, Mauro; Speranza, Maurizio

2007-04-14

The R2PI-TOF spectra of supersonically expanded rare gas/chiral arene heteroclusters have been rationalized in terms of the distortion of the pi-electron density reflecting the different dipole and quadrupole momenta induced in the rare gas atoms by interaction with the opposite pi-faces of the chiral arene itself.

General gauge mediation in five dimensions

DOE Office of Scientific and Technical Information (OSTI.GOV)

McGarrie, Moritz; Russo, Rodolfo

2010-08-01

We use the ''general gauge mediation'' (GGM) formalism to describe a five-dimensional setup with an S{sup 1}/Z{sub 2} orbifold. We first consider a model independent supersymmetry breaking hidden sector on one boundary and generic chiral matter on another. Using the definition of GGM, the effects of the hidden sector are contained in a set of global symmetry current correlator functions and is mediated through the bulk. We find the gaugino, sfermion and hyperscalar mass formulas for minimal and generalized messengers in different regimes of a large, small and intermediate extra dimension. Then we use the five-dimensional GGM formalism to constructmore » a model in which an SU(5) Intriligator, Seiberg and Shih (ISS) model is located on the hidden boundary. We weakly gauge a global symmetry of the ISS model and associate it with the bulk vector superfield. Compared to four-dimensional GGM, there is a natural way to adjust the gaugino versus sfermion mass ratio by a factor (Ml){sup 2}, where M is a characteristic mass scale of the supersymmetry breaking sector and l is the length of the extra dimension.« less

Magnetic fields and chiral asymmetry in the early hot universe

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sydorenko, Maksym; Shtanov, Yuri; Tomalak, Oleksandr, E-mail: maxsydorenko@gmail.com, E-mail: tomalak@uni-mainz.de, E-mail: shtanov@bitp.kiev.ua

In this paper, we study analytically the process of external generation and subsequent free evolution of the lepton chiral asymmetry and helical magnetic fields in the early hot universe. This process is known to be affected by the Abelian anomaly of the electroweak gauge interactions. As a consequence, chiral asymmetry in the fermion distribution generates magnetic fields of non-zero helicity, and vice versa. We take into account the presence of thermal bath, which serves as a seed for the development of instability in magnetic field in the presence of externally generated lepton chiral asymmetry. The developed helical magnetic field andmore » lepton chiral asymmetry support each other, considerably prolonging their mutual existence, in the process of 'inverse cascade' transferring magnetic-field power from small to large spatial scales. For cosmologically interesting initial conditions, the chiral asymmetry and the energy density of helical magnetic field are shown to evolve by scaling laws, effectively depending on a single combined variable. In this case, the late-time asymptotics of the conformal chiral chemical potential reproduces the universal scaling law previously found in the literature for the system under consideration. This regime is terminated at lower temperatures because of scattering of electrons with chirality change, which exponentially washes out chiral asymmetry. We derive an expression for the termination temperature as a function of the chiral asymmetry and energy density of helical magnetic field.« less

Magnetic fields and chiral asymmetry in the early hot universe

NASA Astrophysics Data System (ADS)

Sydorenko, Maksym; Tomalak, Oleksandr; Shtanov, Yuri

2016-10-01

In this paper, we study analytically the process of external generation and subsequent free evolution of the lepton chiral asymmetry and helical magnetic fields in the early hot universe. This process is known to be affected by the Abelian anomaly of the electroweak gauge interactions. As a consequence, chiral asymmetry in the fermion distribution generates magnetic fields of non-zero helicity, and vice versa. We take into account the presence of thermal bath, which serves as a seed for the development of instability in magnetic field in the presence of externally generated lepton chiral asymmetry. The developed helical magnetic field and lepton chiral asymmetry support each other, considerably prolonging their mutual existence, in the process of `inverse cascade' transferring magnetic-field power from small to large spatial scales. For cosmologically interesting initial conditions, the chiral asymmetry and the energy density of helical magnetic field are shown to evolve by scaling laws, effectively depending on a single combined variable. In this case, the late-time asymptotics of the conformal chiral chemical potential reproduces the universal scaling law previously found in the literature for the system under consideration. This regime is terminated at lower temperatures because of scattering of electrons with chirality change, which exponentially washes out chiral asymmetry. We derive an expression for the termination temperature as a function of the chiral asymmetry and energy density of helical magnetic field.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Granados, Carlos; Weiss, Christian

The nucleon's peripheral transverse charge and magnetization densities are computed in chiral effective field theory. The densities are represented in first-quantized form, as overlap integrals of chiral light-front wave functions describing the transition of the nucleon to soft pion-nucleon intermediate states. The orbital motion of the pion causes a large left-right asymmetry in a transversely polarized nucleon. As a result, the effect attests to the relativistic nature of chiral dynamics [pion momenta k = O(M π)] and could be observed in form factor measurements at low momentum transfer.

Chiral separation of norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, and three benzoin derivatives using amino acid based molecular micelles.

PubMed

Billiot, Fereshteh H; Billiot, Eugene J; Ng, Yuen Kwun; Warner, Isiah M

2006-02-01

In this study, 18 polymeric single amino acid and dipeptide surfactants are examined, and their performances, in terms of enantioselectivity, are compared for norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, benzoin, benzoin methyl, and benzoin ethyl enantiomers. Several aspects of amino acid-based polymeric surfactants including comparison of single amino acid versus dipeptide, amino acid order, steric effect, and effect of the position of the chiral center of dipeptide surfactants on the chiral selectivity of these optically active compounds are discussed.

Doped Chiral Polymer Metamaterials

NASA Technical Reports Server (NTRS)

Kang, Jin Ho (Inventor); Gordon, Keith L. (Inventor); Sauti, Godfrey (Inventor); Bryant, Robert G. (Inventor); Park, Cheol (Inventor); Lowther, Sharon E. (Inventor)

2017-01-01

Some implementations provide a composite material that includes a first material and a second material. In some implementations, the composite material is a metamaterial. The first material includes a chiral polymer (e.g., crystalline chiral helical polymer, poly-.gamma.-benzyl-L-glutamate (PBLG), poly-L-lactic acid (PLA), polypeptide, and/or polyacetylene). The second material is within the chiral polymer. The first material and the second material are configured to provide an effective index of refraction value for the composite material of 1 or less. In some implementations, the effective index of refraction value for the composite material is negative. In some implementations, the effective index of refraction value for the composite material of 1 or less is at least in a wavelength of one of at least a visible spectrum, an infrared spectrum, a microwave spectrum, and/or an ultraviolet spectrum.

Strangeness S =-1 hyperon-nucleon interactions: Chiral effective field theory versus lattice QCD

NASA Astrophysics Data System (ADS)

Song, Jing; Li, Kai-Wen; Geng, Li-Sheng

2018-06-01

Hyperon-nucleon interactions serve as basic inputs to studies of hypernuclear physics and dense (neutron) stars. Unfortunately, a precise understanding of these important quantities has lagged far behind that of the nucleon-nucleon interaction due to lack of high-precision experimental data. Historically, hyperon-nucleon interactions are either formulated in quark models or meson exchange models. In recent years, lattice QCD simulations and chiral effective field theory approaches start to offer new insights from first principles. In the present work, we contrast the state-of-the-art lattice QCD simulations with the latest chiral hyperon-nucleon forces and show that the leading order relativistic chiral results can already describe the lattice QCD data reasonably well. Given the fact that the lattice QCD simulations are performed with pion masses ranging from the (almost) physical point to 700 MeV, such studies provide a useful check on both the chiral effective field theory approaches as well as lattice QCD simulations. Nevertheless more precise lattice QCD simulations are eagerly needed to refine our understanding of hyperon-nucleon interactions.

Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect

PubMed Central

Karukurichi, Kannan R.; Fei, Xiang; Swyka, Robert A.; Broussy, Sylvain; Shen, Weijun; Dey, Sangeeta; Roy, Sandip K.; Berkowitz, David B.

2015-01-01

This study introduces new methods of screening for and tuning chiral space and in so doing identifies a promising set of chiral ligands for asymmetric synthesis. The carbafructopyranosyl-1,2-diamine(s) and salens constructed therefrom are particularly compelling. It is shown that by removing the native anomeric effect in this ligand family, one can tune chiral ligand shape and improve chiral bias. This concept is demonstrated by a combination of (i) x-ray crystallographic structure determination, (ii) assessment of catalytic performance, and (iii) consideration of the anomeric effect and its underlying dipolar basis. The title ligands were identified by a new mini version of the in situ enzymatic screening (ISES) procedure through which catalyst-ligand combinations are screened in parallel, and information on relative rate and enantioselectivity is obtained in real time, without the need to quench reactions or draw aliquots. Mini-ISES brings the technique into the nanomole regime (200 to 350 nmol catalyst/20 μl organic volume) commensurate with emerging trends in reaction development/process chemistry. The best-performing β-d-carbafructopyranosyl-1,2-diamine–derived salen ligand discovered here outperforms the best known organometallic and enzymatic catalysts for the hydrolytic kinetic resolution of 3-phenylpropylene oxide, one of several substrates examined for which the ligand is “matched.” This ligand scaffold defines a new swath of chiral space, and anomeric effect tunability defines a new concept in shaping that chiral space. Both this ligand set and the anomeric shape-tuning concept are expected to find broad application, given the value of chiral 1,2-diamines and salens constructed from these in asymmetric catalysis. PMID:26501130

Increments to chiral recognition facilitating enantiomer separations of chiral acids, bases, and ampholytes using Cinchona-based zwitterion exchanger chiral stationary phases.

PubMed

Wernisch, Stefanie; Pell, Reinhard; Lindner, Wolfgang

2012-07-01

The intramolecular distances of anion and cation exchanger sites of zwitterionic chiral stationary phases represent potential tuning sites for enantiomer selectivity. In this contribution, we investigate the influence of alkanesulfonic acid chain length and flexibility on enantiomer separations of chiral acids, bases, and amphoteric molecules for six Cinchona alkaloid-based chiral stationary phases in comparison with structurally related anion and cation exchangers. Employing polar-organic elution conditions, we observed an intramolecular counterion effect for acidic analytes which led to reduced retention times but did not impair enantiomer selectivities. Retention of amphoteric analytes is based on simultaneous double ion pairing of their charged functional groups with the acidic and basic sites of the zwitterionic selectors. A chiral center in the vicinity of the strong cation exchanger site is vital for chiral separations of bases. Sterically demanding side chains are beneficial for separations of free amino acids. Enantioseparations of free (un-derivatized) peptides were particularly successful in stationary phases with straight-chain alkanesulfonic acid sites, pointing to a beneficial influence of more flexible moieties. In addition, we observed pseudo-enantiomeric behavior of quinine and quinidine-derived chiral stationary phases facilitating reversal of elution orders for all analytes. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chiral Polychlorinated Biphenyl Transport, Metabolism and Distribution - A Review

PubMed Central

Lehmler, Hans-Joachim; Harrad, Stuart J.; Hühnerfuss, Heinrich; Kania-Korwel, Izabela; Lee, Cindy M.; Lu, Zhe; Wong, Charles S.

2009-01-01

Chirality can be exploited to gain insight into enantioselective fate processes that may otherwise remain undetected because only biological, but not physical and chemical transport and transformation processes in an achiral environment will change enantiomer compositions. This review provides an in-depth overview of the application of chirality to the study of chiral polychlorinated biphenyls (PCBs), an important group of legacy pollutants. Like other chiral compounds, individual PCB enantiomers may interact enantioselectively (or enantiospecifically) with chiral macromolecules, such as cytochrome P-450 enzymes or ryanodine receptors, leading to differences in their toxicological effects and the enantioselective formation of chiral biotransformation products. Species and congener-specific enantiomer enrichment has been demonstrated in environmental compartments, wildlife and mammals, including humans, typically due to a complex combination of biotransformation processes and uptake via the diet by passive diffusion. Changes in the enantiomer composition of chiral PCBs in the environment have been used to understand complex aerobic and anaerobic microbial transformation pathways, to delineate and quantify PCB sources and transport in the environment, to gain insight into the biotransformation of PCBs in aquatic food webs, and to investigate the enantioselective disposition of PCBs and their methylsulfonyl PCBs metabolites in rodents. Overall, changes in chiral signatures are powerful, but currently underutilized tools for studies of environmental and biological processes of PCBs. PMID:20384371

Chiral Symmetry Breaking in Peptide Systems During Formation of Life on Earth.

PubMed

Konstantinov, Konstantin K; Konstantinova, Alisa F

2018-03-01

Chiral symmetry breaking in complex chemical systems with a large number of amino acids and a large number of similar reactions was considered. It was shown that effective averaging over similar reaction channels may result in very weak effective enantioselectivity of forward reactions, which does not allow most of the known models to result in chiral symmetry breaking during formation of life on Earth. Models with simple and catalytic synthesis of a single amino acid, formation of peptides up to length five, and sedimentation of insoluble pair of substances were considered. It was shown that depending on the model and the values of the parameters, chiral symmetry breaking may occur in up to about 10% out of all possible unique insoluble pair combinations even in the absence of any catalytic synthesis and that minimum total number of amino acids in the pair is 5. If weak enantioselective forward catalytic synthesis of amino acids is present, then the number of possible variants, in which chiral symmetry breaking may occur, increases substantially. It was shown that that the most interesting catalysts have zero or one amino acid of "incorrect" chirality. If the parameters of the model are adjusted in such a way to result in an increase of concentration of longer peptides, then catalysts with two amino acids of incorrect chirality start to appear at peptides of length five. Models of chiral symmetry breaking in the presence of epimerization were considered for peptides up to length three. It was shown that the range of parameters in which chiral symmetry breaking could occur significantly shrinks in comparison to previously considered models with peptides up to length two. An experiment of chiral symmetry breaking was proposed. The experiment consists of a three-step cycle: reversible catalytic synthesis of amino acids, reversible synthesis of peptides, and irreversible sedimentation of insoluble substances.

Chiral Symmetry Breaking in Peptide Systems During Formation of Life on Earth

NASA Astrophysics Data System (ADS)

Konstantinov, Konstantin K.; Konstantinova, Alisa F.

2018-03-01

Chiral symmetry breaking in complex chemical systems with a large number of amino acids and a large number of similar reactions was considered. It was shown that effective averaging over similar reaction channels may result in very weak effective enantioselectivity of forward reactions, which does not allow most of the known models to result in chiral symmetry breaking during formation of life on Earth. Models with simple and catalytic synthesis of a single amino acid, formation of peptides up to length five, and sedimentation of insoluble pair of substances were considered. It was shown that depending on the model and the values of the parameters, chiral symmetry breaking may occur in up to about 10% out of all possible unique insoluble pair combinations even in the absence of any catalytic synthesis and that minimum total number of amino acids in the pair is 5. If weak enantioselective forward catalytic synthesis of amino acids is present, then the number of possible variants, in which chiral symmetry breaking may occur, increases substantially. It was shown that that the most interesting catalysts have zero or one amino acid of "incorrect" chirality. If the parameters of the model are adjusted in such a way to result in an increase of concentration of longer peptides, then catalysts with two amino acids of incorrect chirality start to appear at peptides of length five. Models of chiral symmetry breaking in the presence of epimerization were considered for peptides up to length three. It was shown that the range of parameters in which chiral symmetry breaking could occur significantly shrinks in comparison to previously considered models with peptides up to length two. An experiment of chiral symmetry breaking was proposed. The experiment consists of a three-step cycle: reversible catalytic synthesis of amino acids, reversible synthesis of peptides, and irreversible sedimentation of insoluble substances.

Chiral interface at the finite temperature transition point of QCD

NASA Technical Reports Server (NTRS)

Frei, Z.; Patkos, A.

1990-01-01

The domain wall between coexisting chirally symmetric and broken symmetry regions is studied in a saddle point approximation to the effective three-flavor sigma model. In the chiral limit the surface tension varies in the range ((40 to -50)MeV)(exp 3). The width of the domain wall is estimated to be approximately or equal to 4.5 fm.

Exotic meson decays in the environment with chiral imbalance

NASA Astrophysics Data System (ADS)

Andrianov, A. A.; Andrianov, V. A.; Espriu, D.; Iakubovich, A. V.; Putilova, A. E.

2017-10-01

An emergence of Local Parity Breaking (LPB) in central heavy-ion collisions (HIC) at high energies is discussed. LPB in the fireball can be produced by a difference between the number densities of right- and left-handed chiral fermions (Chiral Imbalance) which is implemented by a chiral (axial) chemical potential. The effective meson lagrangian induced by QCD is extended to the medium with Chiral Imbalance and the properties of light scalar and pseudoscalar mesons (π, α0) are analyzed. It is shown that exotic decays of scalar mesons arise as a result of mixing of π and α0 vacuum states in the presence of chiral imbalance. The pion electromagnetic formfactor obtains an unusual parity-odd supplement which generates a photon polarization asymmetry in pion polarizability. We hope that the above pointed indications of LPB can be identified in experiments on LHC, RHIC, CBM FAIR and NICA accelerators.

Chiral liquid crystal colloids

NASA Astrophysics Data System (ADS)

Yuan, Ye; Martinez, Angel; Senyuk, Bohdan; Tasinkevych, Mykola; Smalyukh, Ivan I.

2018-01-01

Colloidal particles disturb the alignment of rod-like molecules of liquid crystals, giving rise to long-range interactions that minimize the free energy of distorted regions. Particle shape and topology are known to guide this self-assembly process. However, how chirality of colloidal inclusions affects these long-range interactions is unclear. Here we study the effects of distortions caused by chiral springs and helices on the colloidal self-organization in a nematic liquid crystal using laser tweezers, particle tracking and optical imaging. We show that chirality of colloidal particles interacts with the nematic elasticity to predefine chiral or racemic colloidal superstructures in nematic colloids. These findings are consistent with numerical modelling based on the minimization of Landau-de Gennes free energy. Our study uncovers the role of chirality in defining the mesoscopic order of liquid crystal colloids, suggesting that this feature may be a potential tool to modulate the global orientated self-organization of these systems.

Thermodynamic properties of the S =1 /2 twisted triangular spin tube

NASA Astrophysics Data System (ADS)

Ito, Takuya; Iino, Chihiro; Shibata, Naokazu

2018-05-01

Thermodynamic properties of the twisted three-leg spin tube under magnetic field are studied by the finite-T density-matrix renormalization group method. The specific heat, spin, and chiral susceptibilities of the infinite system are calculated for both the original and its low-energy effective models. The obtained results show that the presence of the chirality is observed as a clear peak in the specific heat at low temperature and the contribution of the chirality dominates the low-temperature part of the specific heat as the exchange coupling along the spin tube decreases. The peak structures in the specific heat, spin, and chiral susceptibilities are strongly modified near the quantum phase transition where the critical behaviors of the spin and chirality correlations change. These results confirm that the chirality plays a major role in characteristic low-energy behaviors of the frustrated spin systems.

DNA-bridged Chiroplasmonic Assemblies of Nanoparticles

NASA Astrophysics Data System (ADS)

Kotov, Nicholas

2015-03-01

Chirality at nanoscale attracts a lot of attention during the last decade. A number of chiral nanoscale systems had been discovered ranging from individual nanoparticles to helical nanowires and from lithographically defined substrates. DNA bridges make possible in-silico engineering and practical construction of complex assemblies of nanoparticles with of both plasmonic and excitonic nature. In this presentation, expected and unexpected optical effects that we observed in chiral plasmonic and excitonic systems will be demonstrated. Special effort will be placed on the transitioning of theoretical and experimental knowledge about chiral nanoscale systems to applications. The most obvious direction for practical targets was so far, the design of metamaterials for negative refractive index optics. The results describing the 3D materials with the highest experimentally observed chiral anisotropy factor will be presented. It will be followed by the discussion of the recent developments in analytical application of chiral assemblies for detection of cancer and bacterial contamination.

Bulky melamine-based Zn-porphyrin tweezer as a CD probe of molecular chirality.

PubMed

Petrovic, Ana G; Vantomme, Ghislaine; Negrón-Abril, Yashira L; Lubian, Elisa; Saielli, Giacomo; Menegazzo, Ileana; Cordero, Roselynn; Proni, Gloria; Nakanishi, Koji; Carofiglio, Tommaso; Berova, Nina

2011-10-01

The transfer of chirality from a guest molecule to an achiral host is the subject of significant interest especially when, upon chiral induction, the chiroptical response of the host/guest complex can effectively report the absolute configuration (AC) of the guest. For more than a decade, dimeric metalloporphyrin hosts (tweezers) have been successfully applied as chirality probes for determination of the AC for a wide variety of chiral synthetic compounds and natural products. The objective of this study is to investigate the utility of a new class of melamine-bridged Zn-porphyrin tweezers as sensitive AC reporters. A combined approach based on an experimental CD analysis and a theoretical prediction of the prevailing interporphyrin helicity demonstrates that these tweezers display favorable properties for chiral recognition. Herein, we discuss the application of the melamine-bridged tweezer to the chiral recognition of a diverse set of chiral guests, such as 1,2-diamines, α-amino-esters and amides, secondary alcohols, and 1,2-amino-alcohols. The bulky periphery and the presence of a rigid porphyrin linkage lead, in some cases, to a more enhanced CD sensitivity than that reported earlier with other tweezers. Copyright © 2011 Wiley-Liss, Inc.

Broken chiral symmetry on a null plane

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beane, Silas R., E-mail: silas@physics.unh.edu

2013-10-15

On a null-plane (light-front), all effects of spontaneous chiral symmetry breaking are contained in the three Hamiltonians (dynamical Poincaré generators), while the vacuum state is a chiral invariant. This property is used to give a general proof of Goldstone’s theorem on a null-plane. Focusing on null-plane QCD with N degenerate flavors of light quarks, the chiral-symmetry breaking Hamiltonians are obtained, and the role of vacuum condensates is clarified. In particular, the null-plane Gell-Mann–Oakes–Renner formula is derived, and a general prescription is given for mapping all chiral-symmetry breaking QCD condensates to chiral-symmetry conserving null-plane QCD condensates. The utility of the null-planemore » description lies in the operator algebra that mixes the null-plane Hamiltonians and the chiral symmetry charges. It is demonstrated that in a certain non-trivial limit, the null-plane operator algebra reduces to the symmetry group SU(2N) of the constituent quark model. -- Highlights: •A proof (the first) of Goldstone’s theorem on a null-plane is given. •The puzzle of chiral-symmetry breaking condensates on a null-plane is solved. •The emergence of spin-flavor symmetries in null-plane QCD is demonstrated.« less

Coupling mesodomain positional ordering to intra-domain orientational ordering in block copolymer assembly

NASA Astrophysics Data System (ADS)

Burke, Christopher; Reddy, Abhiram; Prasad, Ishan; Grason, Gregory

Block copolymer (BCP) melts form a number of symmetric microphases, e.g. columnar or double gyroid phases. BCPs with a block composed of chiral monomers are observed to form bulk phases with broken chiral symmetry e.g. a phase of hexagonally ordered helical mesodomains. Other new structures may be possible, e.g. double gyroid with preferred chirality which has potential photonic applications. One approach to understanding chirality transfer from monomer to the bulk is to use self consistent field theory (SCFT) and incorporate an orientational order parameter with a preference for handed twist in chiral block segments, much like the texture of cholesteric liquid crystal. Polymer chains in achiral BCPs exhibit orientational ordering which couples to the microphase geometry; a spontaneous preference for ordering may have an effect on the geometry. The influence of a preference for chiral polar (vectorial) segment order has been studied to some extent, though the influence of coupling to chiral tensorial (nematic) order has not yet been developed. We present a computational approach using SCFT with vector and tensor order which employs well developed pseudo-spectral methods. Using this we explore how tensor order influences which structures form, and if it can promote chiral phases.

Chiral quantum dot based materials

NASA Astrophysics Data System (ADS)

Govan, Joseph; Loudon, Alexander; Baranov, Alexander V.; Fedorov, Anatoly V.; Gun'ko, Yurii

2014-05-01

Recently, the use of stereospecific chiral stabilising molecules has also opened another avenue of interest in the area of quantum dot (QD) research. The main goal of our research is to develop new types of technologically important quantum dot materials containing chiral defects, study their properties and explore their applications. The utilisation of chiral penicillamine stabilisers allowed the preparation of new water soluble white emitting CdS quantum nanostructures which demonstrated circular dichroism in the band-edge region of the spectrum. It was also demonstrated that all three types of QDs (D-, L-, and Rac penicillamine stabilised) show very broad emission bands between 400 and 700 nm due to defects or trap states on the surfaces of the nanocrystals. In this work the chiral CdS based quantum nanostructures have also been doped by copper metal ions and new chiral penicilamine stabilized CuS nanoparticles have been prepared and investigated. It was found that copper doping had a strong effect at low levels in the synthesis of chiral CdS nanostructures. We expect that this research will open new horizons in the chemistry of chiral nanomaterials and their application in biotechnology, sensing and asymmetric synthesis.

Partial restoration of chiral symmetry in a confining string

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kharzeev, Dmitri E.; Loshaj, F.

2014-08-01

Here, we attempt to describe the interplay of confinement and chiral symmetry breaking in QCD by using the string model. We argue that in the quasi-Abelian picture of confinement based on the condensation of magnetic monopoles and the dual Meissner effect, the world sheet dynamics of the confining string can be effectively described by the 1+1 dimensional massless electrodynamics, which is exactly soluble. The transverse plane distribution of the chromoelectric field stretched between the quark and antiquark sources can then be attributed to the fluctuations in the position of the string. The dependence of the chiral condensate in the stringmore » on the (chromo-)electric field can be evaluated analytically, and is determined by the chiral anomaly and the θ-vacuum structure. Moreover, our picture allows us to predict the distribution of the chiral condensate in the plane transverse to the axis connecting the quark and antiquark. This prediction is compared to the lattice QCD results; a good agreement is found.« less

Chiral Selective Chemistry Induced by Natural Selection of Spin-Polarized Electrons.

PubMed

Rosenberg, Richard A; Mishra, Debabrata; Naaman, Ron

2015-06-15

The search to understand the origin of homochirality in nature has been ongoing since the time of Pasteur. Previous work has shown that DNA can act as a spin filter for low-energy electrons and that spin-polarized secondary electrons produced by X-ray irradiation of a magnetic substrate can induce chiral selective chemistry. In the present work it is demonstrated that secondary electrons from a substrate that are transmitted through a chiral overlayer cause enantiomeric selective chemistry in an adsorbed adlayer. We determine the quantum yields (QYs) for dissociation of (R)- or (S)-epichlorohydrin adsorbed on a chiral self-assembled layer of DNA on gold and on bare gold (for control). The results show that there is a significant difference in the QYs between the two enantiomers when adsorbed on DNA, but none when they are adsorbed on bare Au. We propose that the effect results from natural spin filtering effects cause by the chiral monolayer. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Handedness Dependent Electromagnetically Induced Transparency in Hybrid Chiral Metamaterials

NASA Astrophysics Data System (ADS)

Kang, Lei; Hao Jiang, Zhi; Yue, Taiwei; Werner, Douglas H.

2015-07-01

We provide the first experimental demonstration of the handedness dependent electromagnetically induced transparency (EIT) in chiral metamaterials during the interaction with circularly polarized waves. The observed chiral-sensitive EIT phenomena arise from the coherent excitation of a non-radiative mode in the component split ring resonators (SRRs) produced by the corresponding Born-Kuhn type (radiative) resonators that are responsible for the pronounced chirality. The coherent coupling, which is dominated by the bonding and antibonding resonances of the Born-Kuhn type resonators, leads to an extremely steep dispersion for a circularly polarized wave of predefined handedness. Accordingly, retrieved effective medium parameters from simulated results further reveal a difference of 80 in the group indices for left- and right-handed circularly polarized waves at frequencies within the EIT window, which can potentially result in handedness-sensitive pulse delays. These chiral metamaterials which enable a handedness dependent EIT effect may provide more degrees of freedom for designing circular polarization based communication devices.

Membrane rafts stabilized by chiral liquid crystal correction to bare interfacial tension

NASA Astrophysics Data System (ADS)

Kang, Louis; Lubensky, T. C.

Lipid rafts are hypothesized to facilitate protein interaction, tension regulation, and trafficking in biological membranes, but the mechanisms responsible for their formation and maintenance are not clear. Recently, experiments showed that bidisperse mixtures of filamentous viruses can self-assemble into colloidal monolayers with thermodynamically stable rafts that exhibit chiral structure and repulsive interactions. We quantitatively explain these observations by modeling the membrane particles as chiral liquid crystals. Chiral twist promotes the formation of finite-sized rafts by decreasing the effective interfacial tension between rafts and background membrane. It also mediates a repulsion that distributes rafts evenly throughout the membrane. Although this system is composed of filamentous viruses whose aggregation is entropically driven by dextran depletants instead of phospholipids and cholesterol with prominent electrostatic interactions, colloidal and biological membranes share many of the same physical symmetries. Chiral twist can contribute to the behavior of both systems and may account for certain stereospecific effects observed in molecular membranes.

Unusual dimeric tetrahydroxanthone derivatives from Aspergillus lentulus and the determination of their axial chiralities

NASA Astrophysics Data System (ADS)

Li, Tian-Xiao; Yang, Ming-Hua; Wang, Ying; Wang, Xiao-Bing; Luo, Jun; Luo, Jian-Guang; Kong, Ling-Yi

2016-12-01

The research on secondary metabolites of Aspergillus lentulus afforded eight unusual heterodimeric tetrahydroxanthone derivatives, lentulins A-H (2-9), along with the known compound neosartorin (1). Compounds 1-6 exhibited potent antimicrobial activities especially against methicillin-resistant Staphylococci. Their absolute configurations, particularly the axial chiralities, were unambiguously demonstrated by a combination of electronic circular dichroism (ECD), Rh2(OCOCF3)4-induced ECD experiments, modified Mosher methods, and chemical conversions. Interestingly, compounds 1-4 were the first samples of atropisomers within the dimeric tetrahydroxanthone class. Further investigation of the relationships between their axial chiralities and ECD Cotton effects led to the proposal of a specific CD Exciton Chirality rule to determine the axial chiralities in dimeric tetrahydroxanthones and their derivatives.

Lanthanide tris(β-diketonates) as useful probes for chirality determination of biological amino alcohols in vibrational circular dichroism: ligand to ligand chirality transfer in lanthanide coordination sphere.

PubMed

Miyake, Hiroyuki; Terada, Keiko; Tsukube, Hiroshi

2014-06-01

A series of lanthanide tris(β-diketonates) functioned as useful chirality probes in the vibrational circular dichroism (VCD) characterization of biological amino alcohols. Various chiral amino alcohols induced intense VCD signals upon ternary complexation with racemic lanthanide tris(β-diketonates). The VCD signals observed around 1500 cm(-1) (β-diketonate IR absorption region) correlated well with the stereochemistry and enantiomeric purity of the targeted amino alcohol, while the corresponding monoalcohol, monoamine, and diol substrates induced very weak VCD signals. The high-coordination number and dynamic property of the lanthanide complex offer an effective chirality VCD probing of biological substrates. © 2014 Wiley Periodicals, Inc.

A theoretical study of potentially observable chirality-sensitive NMR effects in molecules.

PubMed

Garbacz, Piotr; Cukras, Janusz; Jaszuński, Michał

2015-09-21

Two recently predicted nuclear magnetic resonance effects, the chirality-induced rotating electric polarization and the oscillating magnetization, are examined for several experimentally available chiral molecules. We discuss in detail the requirements for experimental detection of chirality-sensitive NMR effects of the studied molecules. These requirements are related to two parameters: the shielding polarizability and the antisymmetric part of the nuclear magnetic shielding tensor. The dominant second contribution has been computed for small molecules at the coupled cluster and density functional theory levels. It was found that DFT calculations using the KT2 functional and the aug-cc-pCVTZ basis set adequately reproduce the CCSD(T) values obtained with the same basis set. The largest values of parameters, thus most promising from the experimental point of view, were obtained for the fluorine nuclei in 1,3-difluorocyclopropene and 1,3-diphenyl-2-fluoro-3-trifluoromethylcyclopropene.

Spontaneous chiral symmetry breaking in metamaterials

NASA Astrophysics Data System (ADS)

Liu, Mingkai; Powell, David A.; Shadrivov, Ilya V.; Lapine, Mikhail; Kivshar, Yuri S.

2014-07-01

Spontaneous chiral symmetry breaking underpins a variety of areas such as subatomic physics and biochemistry, and leads to an impressive range of fundamental phenomena. Here we show that this prominent effect is now available in artificial electromagnetic systems, enabled by the advent of magnetoelastic metamaterials where a mechanical degree of freedom leads to a rich variety of strong nonlinear effects such as bistability and self-oscillations. We report spontaneous symmetry breaking in torsional chiral magnetoelastic structures where two or more meta-molecules with opposite handedness are electromagnetically coupled, modifying the system stability. Importantly, we show that chiral symmetry breaking can be found in the stationary response of the system, and the effect is successfully demonstrated in a microwave pump-probe experiment. Such symmetry breaking can lead to a giant nonlinear polarization change, energy localization and mode splitting, which provides a new possibility for creating an artificial phase transition in metamaterials, analogous to that in ferrimagnetic domains.

Spontaneous chiral symmetry breaking in metamaterials.

PubMed

Liu, Mingkai; Powell, David A; Shadrivov, Ilya V; Lapine, Mikhail; Kivshar, Yuri S

2014-07-18

Spontaneous chiral symmetry breaking underpins a variety of areas such as subatomic physics and biochemistry, and leads to an impressive range of fundamental phenomena. Here we show that this prominent effect is now available in artificial electromagnetic systems, enabled by the advent of magnetoelastic metamaterials where a mechanical degree of freedom leads to a rich variety of strong nonlinear effects such as bistability and self-oscillations. We report spontaneous symmetry breaking in torsional chiral magnetoelastic structures where two or more meta-molecules with opposite handedness are electromagnetically coupled, modifying the system stability. Importantly, we show that chiral symmetry breaking can be found in the stationary response of the system, and the effect is successfully demonstrated in a microwave pump-probe experiment. Such symmetry breaking can lead to a giant nonlinear polarization change, energy localization and mode splitting, which provides a new possibility for creating an artificial phase transition in metamaterials, analogous to that in ferrimagnetic domains.

Infrared computations of defect Schur indices

DOE PAGES

Córdova, Clay; Gaiotto, Davide; Shao, Shu-Heng

2016-11-18

We conjecture a formula for the Schur index of four-dimensional N = 2 theories in the presence of boundary conditions and/or line defects, in terms of the low-energy effective Seiberg-Witten description of the system together with massive BPS excitations. We test our proposal in a variety of examples for SU(2) gauge theories, either conformal or asymptotically free. We use the conjecture to compute these defect-enriched Schur indices for theories which lack a Lagrangian description, such as Argyres-Douglas theories. We demonstrate in various examples that line defect indices can be expressed as sums of characters of the associated two-dimensional chiral algebramore » and that for Argyres-Douglas theories the line defect OPE reduces in the index to the Verlinde algebra.« less

Infrared computations of defect Schur indices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Córdova, Clay; Gaiotto, Davide; Shao, Shu-Heng

We conjecture a formula for the Schur index of four-dimensional N = 2 theories in the presence of boundary conditions and/or line defects, in terms of the low-energy effective Seiberg-Witten description of the system together with massive BPS excitations. We test our proposal in a variety of examples for SU(2) gauge theories, either conformal or asymptotically free. We use the conjecture to compute these defect-enriched Schur indices for theories which lack a Lagrangian description, such as Argyres-Douglas theories. We demonstrate in various examples that line defect indices can be expressed as sums of characters of the associated two-dimensional chiral algebramore » and that for Argyres-Douglas theories the line defect OPE reduces in the index to the Verlinde algebra.« less

Study on the determination and chiral inversion of R-salbutamol in human plasma and urine by liquid chromatography-tandem mass spectrometry.

PubMed

Zhou, Ting; Zeng, Jing; Liu, Shan; Zhao, Ting; Wu, Jie; Lai, Wenshi; He, Mingzhi; Xu, Beining; Qu, Shanshan; Xu, Ling; Tan, Wen

2015-10-01

The chiral inversion has been a concerned issue during the research and development of a chiral drug. In this study, a sensitive chiral liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of salbutamol enantiomers in human plasma and urine. The chiral inversion mechanism of R-salbutamol was fully investigated for the first time by studying the effects of physicochemical factors, including pH, temperature and time. A fitted model to predict the chiral inversion ratio of R-salbutamol was proposed using a Box-Behnken design. All the samples were separated on an Astec Chirobiotic T column and detected by a tandem mass spectrometer in multiple reaction monitoring mode. Lower limit of quantification of 0.100ng/mL was achieved under the optimized conditions. The method was fully validated and successfully applied to the clinical pharmacokinetic study of R-salbutamol in healthy volunteers. Chiral inversion of R-salbutamol to S-salbutamol has been detected in urine samples. The results indicated that pH and temperature were two dominant factors that caused the chiral inversion of R-salbutamol, which should be taken into consideration during the analysis of chiral drugs. The chiral inversion of R-salbutamol determined in this study was confirmed resulted from the gastric acid in stomach rather than caused by the analysis conditions. Moreover, the calculated results of the fitted model matched very well with the enantioselective pharmacokinetic study of R-salbutamol, and the individual difference of the chiral inversion ratio of R-salbutamol was related to the individual gastric environment. On the basis of the results, this study provides important and concrete information not only for the chiral analysis but also for the metabolism research of chiral drugs. Copyright © 2015 Elsevier B.V. All rights reserved.

Generalized Oseen transformation for and enhancement of Bragg characteristics of electro-optic structurally chiral materials

NASA Astrophysics Data System (ADS)

Lakhtakia, Akhlesh

2006-05-01

The Oseen transformation is generalized to define a non-electro-optic structurally chiral material, wherein propagation along the axis of chirality is equivalent to that in an electro-optic SCM with local 4¯2m point group symmetry. This generalization shows that the exploitation of the Pockels effect amounts to an enhancement of the effective local birefringence, which in turn can enhance the characteristics of the circular Bragg phenomenon. Electro-optic SCMs can therefore serve as efficient and electrically controllable circular- and elliptical-polarization rejection filters.

Chiral Symmetry Breaking in Crystal Growth: Is Hydrodynamic Convection Relevant?

NASA Technical Reports Server (NTRS)

Martin, B.; Tharrington, A.; Wu, Xiao-Lun

1996-01-01

The effects of mechanical stirring on nucleation and chiral symmetry breaking have been investigated for a simple inorganic molecule, sodium chlorate (NaClO3). In contrast to earlier findings, our experiment suggests that the symmetry breaking may have little to do with hydrodynamic convection. Rather the effect can be reasonably accounted for by mechanical damage to incipient crystals. The catastrophic events, creating numerous small 'secondary' crystals, produce statistical domination of one chiral species over the other. Our conclusion is supported by a number of observations using different mixing mechanisms.

Nucleation and chiral symmetry breaking under controlled hydrodynamic flows

NASA Technical Reports Server (NTRS)

Wu, Xiao-Lun; Martin, Brian; Tharrington, Arnold

1994-01-01

The effects of hydrodynamic convection on nucleation and broken chiral symmetry have been investigated for a simple inorganic molecule, sodium chlorate (NaClO3). Our experiment suggests that the symmetry breaking is a result of hydrodynamic amplification of rare nucleation events. The effect is more pronounced when the primary nucleation occurs on the solute-vapor interface, where mixing in the surface sublayer becomes important. The transition from the achiral to the chiral states appears to be smooth as the hydrodynamic parameters, such as flow rate, are varied.

Toroidal Interaction and Propeller Chirality of Hexaarylbenzenes. Dynamic Domino Inversion Revealed by Combined Experimental and Theoretical Circular Dichroism Studies.

PubMed

Kosaka, Tomoyo; Inoue, Yoshihisa; Mori, Tadashi

2016-03-03

Hexaarylbenzenes (HABs) have greatly attracted much attention due to their unique propeller-shaped structure and potential application in materials science, such as liquid crystals, molecular capsules/rotors, redox materials, nonlinear optical materials, as well as molecular wires. Less attention has however been paid to their propeller chirality. By introducing small point-chiral group(s) at the periphery of HABs, propeller chirality was effectively induced, provoking strong Cotton effects in the circular dichroism (CD) spectrum. Temperature and solvent polarity manipulate the dynamics of propeller inversion in solution. As such, whizzing toroids become more substantial in polar solvents and at an elevated temperature, where radial aromatic rings (propeller blades) prefer orthogonal alignment against the central benzene ring (C6 core), maximizing toroidal interactions.

Contractile and chiral activities codetermine the helicity of swimming droplet trajectories

NASA Astrophysics Data System (ADS)

Tjhung, Elsen; Cates, Michael E.; Marenduzzo, Davide

2017-05-01

Active fluids are a class of nonequilibrium systems where energy is injected into the system continuously by the constituent particles themselves. Many examples, such as bacterial suspensions and actomyosin networks, are intrinsically chiral at a local scale, so that their activity involves torque dipoles alongside the force dipoles usually considered. Although many aspects of active fluids have been studied, the effects of chirality on them are much less known. Here, we study by computer simulation the dynamics of an unstructured droplet of chiral active fluid in three dimensions. Our model considers only the simplest possible combination of chiral and achiral active stresses, yet this leads to an unprecedented range of complex motilities, including oscillatory swimming, helical swimming, and run-and-tumble motion. Strikingly, whereas the chirality of helical swimming is the same as the microscopic chirality of torque dipoles in one regime, the two are opposite in another. Some of the features of these motility modes resemble those of some single-celled protozoa, suggesting that underlying mechanisms may be shared by some biological systems and synthetic active droplets.

Ferroelectric nanostructure having switchable multi-stable vortex states

DOEpatents

Naumov, Ivan I [Fayetteville, AR; Bellaiche, Laurent M [Fayetteville, AR; Prosandeev, Sergey A [Fayetteville, AR; Ponomareva, Inna V [Fayetteville, AR; Kornev, Igor A [Fayetteville, AR

2009-09-22

A ferroelectric nanostructure formed as a low dimensional nano-scale ferroelectric material having at least one vortex ring of polarization generating an ordered toroid moment switchable between multi-stable states. A stress-free ferroelectric nanodot under open-circuit-like electrical boundary conditions maintains such a vortex structure for their local dipoles when subject to a transverse inhomogeneous static electric field controlling the direction of the macroscopic toroidal moment. Stress is also capable of controlling the vortex's chirality, because of the electromechanical coupling that exists in ferroelectric nanodots.

Understanding Cooperative Chirality at the Nanoscale

NASA Astrophysics Data System (ADS)

Yu, Shangjie; Wang, Pengpeng; Govorov, Alexander; Ouyang, Min

Controlling chirality of organic and inorganic structures plays a key role in many physical, chemical and biochemical processes, and may offer new opportunity to create technology applications based on chiroptical effect. In this talk, we will present a theoretical model and simulation to demonstrate how to engineer nanoscale chirality in inorganic nanostructures via synergistic control of electromagnetic response of both lattice and geometry, leading to rich tunability of chirality at the nanoscale. Our model has also been applied to understand recent materials advancement of related control with excellent agreement, and can elucidate physical origins of circular dichroism features in the experiment.

Effective Hamiltonian Approach to Optical Activity in Weyl Spin–Orbit System

NASA Astrophysics Data System (ADS)

Kawaguchi, Hideo; Tatara, Gen

2018-06-01

Chirality or handedness in condensed matter induces anomalous optical responses such as natural optical activity, rotation of the plane of light polarization, as a result of breaking of spatial-inversion symmetry. In this study, optical properties of a Weyl spin-orbit system with quadratic dispersion, a typical chiral system invariant under time-reversal, are investigated theoretically by deriving an effective Hamiltonian based on an imaginary-time path-integral formalism. We show that the effective Hamiltonian can indeed be written in terms of an optical chirality order parameter suggested by Lipkin. The natural optical activity is discussed on the basis of the Hamiltonian.

Structure and properties of composite films formed by cellulose nanocrystals and charged latex nanoparticles

NASA Astrophysics Data System (ADS)

Thérien-Aubin, Héloïse; Lukach, Ariella; Pitch, Natalie; Kumacheva, Eugenia

2015-04-01

We report the structural and optical properties of composite films formed from mixed suspensions of cellulose nanocrystals (CNCs) and fluorescent latex nanoparticles (NPs). We explored the effect of NP concentration, size, surface charge, glass transition temperature and film processing conditions on film structure and properties. The chiral nematic order, typical of CNC films, was preserved in films with up to 50 wt% of negatively-charged latex NPs. Composite films were characterized by macroscopically close-to-uniform fluorescence, birefringence, and circular dichroism properties. In contrast, addition of positively charged latex NPs led to gelation of CNC-latex suspensions and disruption of the chiral nematic order in the composite films. Large latex NPs disrupted the chiral nematic order to a larger extend than small NPs. Furthermore, the glass transition of latex NPs had a dramatic effect on the structure of CNC-latex films. Latex particles in the rubbery state were easily incorporated in the ordered CNC matrix and improved the structural integrity of its chiral nematic phase.We report the structural and optical properties of composite films formed from mixed suspensions of cellulose nanocrystals (CNCs) and fluorescent latex nanoparticles (NPs). We explored the effect of NP concentration, size, surface charge, glass transition temperature and film processing conditions on film structure and properties. The chiral nematic order, typical of CNC films, was preserved in films with up to 50 wt% of negatively-charged latex NPs. Composite films were characterized by macroscopically close-to-uniform fluorescence, birefringence, and circular dichroism properties. In contrast, addition of positively charged latex NPs led to gelation of CNC-latex suspensions and disruption of the chiral nematic order in the composite films. Large latex NPs disrupted the chiral nematic order to a larger extend than small NPs. Furthermore, the glass transition of latex NPs had a dramatic effect on the structure of CNC-latex films. Latex particles in the rubbery state were easily incorporated in the ordered CNC matrix and improved the structural integrity of its chiral nematic phase. Electronic supplementary information (ESI) available: Detailed latex synthesis. Additional characterization of the nanoparticles and films. See DOI: 10.1039/c5nr00660k

Drag suppression in anomalous chiral media

DOE PAGES

Sadofyev, Andrey V.; Yin, Yi

2016-06-01

We study a heavy impurity moving longitudinal with the direction of an external magnetic field in an anomalous chiral medium. Such system would carry a non-dissipative current of chiral magnetic effect associated with the anomaly. We show, by generalizing Landau's criterion for super fluidity, that the "anomalous component" which gives rise to the anomalous transport will not contribute to the drag experienced by an impurity. We argue on a very general basis that those systems with a strong magnetic field would exhibit an interesting transport phenomenon$-$the motion of the heavy impurity is frictionless, in analogy to the case of amore » super fluid. Finally, we demonstrate and confirm our general results with two complementary examples: weakly coupled chiral fermion gases and strongly interacting chiral liquids.« less

Matching Pion-Nucleon Roy-Steiner Equations to Chiral Perturbation Theory.

PubMed

Hoferichter, Martin; Ruiz de Elvira, Jacobo; Kubis, Bastian; Meissner, Ulf-G

2015-11-06

We match the results for the subthreshold parameters of pion-nucleon scattering obtained from a solution of Roy-Steiner equations to chiral perturbation theory up to next-to-next-to-next-to-leading order, to extract the pertinent low-energy constants including a comprehensive analysis of systematic uncertainties and correlations. We study the convergence of the chiral series by investigating the chiral expansion of threshold parameters up to the same order and discuss the role of the Δ(1232) resonance in this context. Results for the low-energy constants are also presented in the counting scheme usually applied in chiral nuclear effective field theory, where they serve as crucial input to determine the long-range part of the nucleon-nucleon potential as well as three-nucleon forces.

Matching Pion-Nucleon Roy-Steiner Equations to Chiral Perturbation Theory

NASA Astrophysics Data System (ADS)

Hoferichter, Martin; Ruiz de Elvira, Jacobo; Kubis, Bastian; Meißner, Ulf-G.

2015-11-01

We match the results for the subthreshold parameters of pion-nucleon scattering obtained from a solution of Roy-Steiner equations to chiral perturbation theory up to next-to-next-to-next-to-leading order, to extract the pertinent low-energy constants including a comprehensive analysis of systematic uncertainties and correlations. We study the convergence of the chiral series by investigating the chiral expansion of threshold parameters up to the same order and discuss the role of the Δ (1232 ) resonance in this context. Results for the low-energy constants are also presented in the counting scheme usually applied in chiral nuclear effective field theory, where they serve as crucial input to determine the long-range part of the nucleon-nucleon potential as well as three-nucleon forces.

Signatures of a staggered-flux phase in the t-J model with two holes on a 32-site lattice

NASA Astrophysics Data System (ADS)

Leung, P. W.

2000-09-01

We study the relevance of the staggered-flux phase in the t-J model using a system with two holes on a 32-site lattice with periodic boundary conditions. We find a staggered-flux pattern in the current-current correlation in the lowest energy d-wave state where there is mutual attraction between the holes. This staggered correlation decays faster with distance when the hole binding becomes stronger. This is in complete agreement with a recent study by Ivanov, Lee, and Wen [Phys. Rev. Lett. 84, 3958 (2000)] based on the SU(2) theory, and strongly suggests that the staggered-flux phase is a key ingredient in the t-J model. We further show that this staggered-flux pattern does not exist in a state where the holes repel each other. Correlations of the chirality operator S1.(S2×S3) show that the staggered pattern of the chirality is closely tied to the holes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ackerman, P. J.; van de Lagemaat, J.; Smalyukh, I. I.

Some of the most exotic condensed matter phases, such as twist grain boundary and blue phases in liquid crystals and Abrikosov phases in superconductors, contain arrays of topological defects in their ground state. Comprised of a triangular lattice of double-twist tubes of magnetization, the so-called ‘A-phase’ in chiral magnets is an example of a thermodynamically stable phase with topologically nontrivial solitonic field configurations referred to as two-dimensional skyrmions, or baby-skyrmions. Here we report that three-dimensional skyrmions in the form of double-twist tori called ‘hopfions’, or ‘torons’ when accompanied by additional self-compensating defects, self-assemble into periodic arrays and linear chains thatmore » exhibit electrostriction. In confined chiral nematic liquid crystals, this self-assembly is similar to that of liquid crystal colloids and originates from long-range elastic interactions between particle-like skyrmionic torus knots of molecular alignment field, which can be tuned from isotropic repulsive to weakly or highly anisotropic attractive by low-voltage electric fields.« less

Insights into the Distinguishing Stress-induced Cytotoxicity of Chiral Gold Nanoclusters and the Relationship with GSTP1

PubMed Central

Zhang, Chunlei; Zhou, Zhijun; Zhi, Xiao; Ma, Yue; Wang, Kan; Wang, Yuxia; Zhang, Yingge; Fu, Hualin; Jin, Weilin; Pan, Fei; Cui, Daxiang

2015-01-01

Chiral gold nanoclusters (Au NCs) exhibit attracting properties owing to their unique physical and chemical properties. Herein we report for the first time chiral gold nanoclusters' cytotoxicity and potential molecular mechanism. The L-glutathione (i.e. L-GSH) and D-glutathione (i.e. D-GSH)-capped Au NCs were prepared and characterized by HRTEM, UV-vis, photoluminescence and circular dichroism (CD) spectroscopy. Results showed that the CD spectra of L-glutathione (i.e. L-GSH) and D-glutathione (i.e. D-GSH)-capped Au NCs exhibited multiple bands which were identically mirror-imaged, demonstrating that the chirality of GSH-capped NCs had contributions from both the metal core and the ligand. The effects of AuNCs@L-GSH and AuNCs@D-GSH on cells were similar based on the cell physiology related cytotoxicity, although the effects became more prominent in AuNCs@D-GSH treated cells, including ROS generation, mitochondrial membrane depolarization, cell cycle arrest and apoptosis. Global gene expression and pathway analysis displayed that both AuNCs@L-GSH and AuNCs@D-GSH caused the up-regulation of genes involved in cellular rescue and stress response, while AuNCs@D-GSH individually induced up-regulation of transcripts involved in some metabolic- and biosynthetic-related response. MGC-803 cells were more sensitive to the oxidative stress damage induced by chiral Au NCs than GES-1 cells, which was associated with GSTP1 hypermethylation. In conclusion, chiral gold nanoclusters exhibit this chirality-associated regulation of cytotoxicity, different gene expression profiling and epigenetic changes should be responsible for observed phenomena. Our study highlights the importance of the interplays between chiral materials and biological system at sub-nano level. PMID:25553104

Elevated levels of polychlorinated biphenyls in plants, air, and soils at an E-waste site in Southern China and enantioselective biotransformation of chiral PCBs in plants.

PubMed

Chen, She-Jun; Tian, Mi; Zheng, Jing; Zhu, Zhi-Cheng; Luo, Yong; Luo, Xiao-Jun; Mai, Bi-Xian

2014-04-01

E-waste that contains polychlorinated biphenyls (PCBs) is moved across national boundaries, often from industrialized countries in the northern hemisphere, where the items were formerly used, to subtropical and tropical regions in southeastern Asia and Africa. As a result, there is a high likelihood that PCBs will be released into the environment from a primary source due to the elevated temperatures encountered in these low-latitude regions. In the present study, PCBs and enantiomer fractions (EFs) of chiral PCBs (PCB 84, 95, 132, 136, 149, and 183) were analyzed in air, eucalyptus leaves, pine needles, and soil at an e-waste site and a rural site in southern China. The concentrations of PCBs at the e-waste site ranged from 7825 to 76330 pg/m(3), 27.5 to 1993 ng/g, and 24.2 to 12045 ng/g in the air (gas plus particle), plant leaves, and soils, respectively. The atmospheric PCB composition profiles in the present study indicated relatively high abundances of penta- and hexa-PCBs, which were different from those previously observed in the air across China. The Clausius-Clapeyron regression analysis indicated that evaporation from local contaminated surfaces constitutes a primary emission source of PCBs in the air at the e-waste site. The chiral signatures of PCBs in the air at the e-waste site were essentially racemic (mean EFs = (0.484 ± 0.022)-(0.499 ± 0.004) in the gaseous phase) except for PCB 84 (0.420 ± 0.050), indicating that racemic sources dominate the PCB emission in the air. PCB chiral signatures in the soils ((0.422 ± 0.038)-(0.515 ± 0.016)) were similar to those in the air except for PCB 95. However, the chiral PCBs in the plants (especially the eucalyptus leaves) had significantly nonracemic residues ((0.368 ± 0.075)-(0.561 ± 0.045)) compared to those in the air and soil. This finding suggests that enantioselective biotransformation of these atropisomeric PCBs was very likely to occur in the plant leaves, possibly due to metabolism by cytochrome P-450 enzymes in leaves. To our knowledge, this is the first report on the enantioselective metabolism of chiral PCBs in plants under field conditions.

Characteristics of chiral plasma plumes generated in the absence of external magnetic field

NASA Astrophysics Data System (ADS)

Nie, LanLan; Liu, FengWu; Zhou, XinCai; Lu, XinPei; Xian, YuBin

2018-05-01

A chiral plasma plume has recently been generated inside a dielectric tube without the use of an external magnetic field. In this paper, we seek to further study the key properties of such a chiral plume to improve our understanding of how this interesting structure is generated and controlled. The chiral plume is generated by externally mounting a stainless steel helical coil or a ring onto the dielectric tube. By changing the pitch of the helical coil, the pitch of the plasma plume can be controlled, with the shape of the plume following the shape of the helical coil. The addition of the helical coil significantly expands the range of parameters under which the chiral plasma plume appears. When the frequency of the applied voltage increases, additional stable discharge channels appear between the adjacent helices. The addition of two helical coils results in the formation of two chiral plasma plumes, which follow the shape of the helical coils. When a metal ring is placed on the outside of the tube, there is no chiral plasma plume between the high voltage electrode and the ring; however, a chiral plasma plume appears on the right side of the ring if the distance between the ring and the high voltage electrode is small. These findings suggest that the chiral plasma can be effectively modulated and guided using an externally mounted helical coil, which acts as the floating/actual ground to reduce the impedance of the discharge and as such contributes to the emergence of the chiral plasma plume behavior.

Criteria of backscattering in chiral one-way photonic crystals

NASA Astrophysics Data System (ADS)

Cheng, Pi-Ju; Chang, Shu-Wei

2016-03-01

Optical isolators are important devices in photonic circuits. To reduce the unwanted reflection in a robust manner, several setups have been realized using nonreciprocal schemes. In this study, we show that the propagating modes in a strongly-guided chiral photonic crystal (no breaking of the reciprocity) are not backscattering-immune even though they are indeed insensitive to many types of scatters. Without the protection from the nonreciprocity, the backscattering occurs under certain circumstances. We present a perturbative method to calculate the backscattering of chiral photonic crystals in the presence of chiral/achiral scatters. The model is, essentially, a simplified analogy to the first-order Born approximation. Under reasonable assumptions based on the behaviors of chiral photonic modes, we obtained the expression of reflection coefficients which provides criteria for the prominent backscattering in such chiral structures. Numerical examinations using the finite-element method were also performed and the results agree well with the theoretical prediction. From both our theory and numerical calculations, we find that the amount of backscattering critically depends on the symmetry of scatter cross sections. Strong reflection takes place when the azimuthal Fourier components of scatter cross sections have an order l of 2. Chiral scatters without these Fourier components would not efficiently reflect the chiral photonic modes. In addition, for these chiral propagating modes, disturbances at the most significant parts of field profiles do not necessarily result in the most effective backscattering. The observation also reveals what types of scatters or defects should be avoided in one-way applications of chiral structures in order to minimize the backscattering.

Potential Super-Toughness Behavior of Chiral (10,5) Carbon Nanotubes

DTIC Science & Technology

2006-11-01

1 POTENTIAL SUPER-TOUGHNESS BEHAVIOR OF CHIRAL (10,5) CARBON NANOTUBES C. R. Welch, R. W. Haskins, D. L. Majure , R. M. Ebeling, C. P. Marsh...1 This paper is approved for public release; distribution is unlimited. performance will be a disruptive and positive force ...strengths was due to the effects of molecular defects and chirality of the nanotube structures. Barber et al. (2003), using atomic force microscope

Cytotoxicity of gold nanoparticles with different structures and surface-anchored chiral polymers.

PubMed

Deng, Jun; Yao, Mengyun; Gao, Changyou

2017-04-15

Nanoparticles (NPs) can have profound effects on cell biology. However, the potential adverse effects of gold nanoparticles (AuNPs) with different surface chirality and structures have not been elucidated. In this study, monolayers of poly(acryloyl-l(d)-valine (l(d)-PAV) chiral molecules were anchored on the surfaces of gold nanocubes (AuNCs) and nanooctahedras (AuNOs), respectively. The l-PAV-AuNCs and d-PAV-AuNCs, or the l-PAV-AuNOs and d-PAV-AuNOs, had identical physicochemical properties in terms of size, morphology and ligand density except of the reverse molecular chirality on the particle surfaces, respectively. The l-PAV capped AuNCs and AuNOs exhibited larger cytotoxicity to A549 cells than the D-PAV coated ones, and the PAV-AuNOs had larger cytotoxicity than PAV-AuNCs when being capped with the same type of enantiomers, respectively. The cytotoxicity was positively correlated with the cellular uptake amount, and thereby the production of intracellular reactive oxygen species (ROS). • Gold nanoparticles with different structure and surface chirality are fabricated. • The structure and surface chirality at the nanoscale can influence cytotoxicity and genotoxicity. • A new perspective on designing nanoparticles for drug delivery, bioimaging and diagnosis. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Evanescent-wave and ambient chiral sensing by signal-reversing cavity ringdown polarimetry.

PubMed

Sofikitis, Dimitris; Bougas, Lykourgos; Katsoprinakis, Georgios E; Spiliotis, Alexandros K; Loppinet, Benoit; Rakitzis, T Peter

2014-10-02

Detecting and quantifying chirality is important in fields ranging from analytical and biological chemistry to pharmacology and fundamental physics: it can aid drug design and synthesis, contribute to protein structure determination, and help detect parity violation of the weak force. Recent developments employ microwaves, femtosecond pulses, superchiral light or photoionization to determine chirality, yet the most widely used methods remain the traditional methods of measuring circular dichroism and optical rotation. However, these signals are typically very weak against larger time-dependent backgrounds. Cavity-enhanced optical methods can be used to amplify weak signals by passing them repeatedly through an optical cavity, and two-mirror cavities achieving up to 10(5) cavity passes have enabled absorption and birefringence measurements with record sensitivities. But chiral signals cancel when passing back and forth through a cavity, while the ubiquitous spurious linear birefringence background is enhanced. Even when intracavity optics overcome these problems, absolute chirality measurements remain difficult and sometimes impossible. Here we use a pulsed-laser bowtie cavity ringdown polarimeter with counter-propagating beams to enhance chiral signals by a factor equal to the number of cavity passes (typically >10(3)); to suppress the effects of linear birefringence by means of a large induced intracavity Faraday rotation; and to effect rapid signal reversals by reversing the Faraday rotation and subtracting signals from the counter-propagating beams. These features allow absolute chiral signal measurements in environments where background subtraction is not feasible: we determine optical rotation from α-pinene vapour in open air, and from maltodextrin and fructose solutions in the evanescent wave produced by total internal reflection at a prism surface. The limits of the present polarimeter, when using a continuous-wave laser locked to a stable, high-finesse cavity, should match the sensitivity of linear birefringence measurements (3 × 10(-13) radians), which is several orders of magnitude more sensitive than current chiral detection limits and is expected to transform chiral sensing in many fields.

Field-controlled structures in ferromagnetic cholesteric liquid crystals.

PubMed

Medle Rupnik, Peter; Lisjak, Darja; Čopič, Martin; Čopar, Simon; Mertelj, Alenka

2017-10-01

One of the advantages of anisotropic soft materials is that their structures and, consequently, their properties can be controlled by moderate external fields. Whereas the control of materials with uniform orientational order is straightforward, manipulation of systems with complex orientational order is challenging. We show that a variety of structures of an interesting liquid material, which combine chiral orientational order with ferromagnetic one, can be controlled by a combination of small magnetic and electric fields. In the suspensions of magnetic nanoplatelets in chiral nematic liquid crystals, the platelet's magnetic moments orient along the orientation of the liquid crystal and, consequently, the material exhibits linear response to small magnetic fields. In the absence of external fields, orientations of the liquid crystal and magnetization have wound structure, which can be either homogeneously helical, disordered, or ordered in complex patterns, depending on the boundary condition at the surfaces and the history of the sample. We demonstrate that by using different combinations of small magnetic and electric fields, it is possible to control reversibly the formation of the structures in a layer of the material. In such a way, different periodic structures can be explored and some of them may be suitable for photonic applications. The material is also a convenient model system to study chiral magnetic structures, because it is a unique liquid analog of a solid helimagnet.

Chiral EFT based nuclear forces: achievements and challenges

NASA Astrophysics Data System (ADS)

Machleidt, R.; Sammarruca, F.

2016-08-01

During the past two decades, chiral effective field theory has become a popular tool to derive nuclear forces from first principles. Two-nucleon interactions have been worked out up to sixth order of chiral perturbation theory and three-nucleon forces up to fifth order. Applications of some of these forces have been conducted in nuclear few- and many-body systems—with a certain degree of success. But in spite of these achievements, we are still faced with great challenges. Among them is the issue of a proper uncertainty quantification of predictions obtained when applying these forces in ab initio calculations of nuclear structure and reactions. A related problem is the order by order convergence of the chiral expansion. We start this review with a pedagogical introduction and then present the current status of the field of chiral nuclear forces. This is followed by a discussion of representative examples for the application of chiral two- and three-body forces in the nuclear many-body system including convergence issues.

Micropatterned mammalian cells exhibit phenotype-specific left-right asymmetry.

PubMed

Wan, Leo Q; Ronaldson, Kacey; Park, Miri; Taylor, Grace; Zhang, Yue; Gimble, Jeffrey M; Vunjak-Novakovic, Gordana

2011-07-26

Left-right (LR) asymmetry (handedness, chirality) is a well-conserved biological property of critical importance to normal development. Changes in orientation of the LR axis due to genetic or environmental factors can lead to malformations and disease. While the LR asymmetry of organs and whole organisms has been extensively studied, little is known about the LR asymmetry at cellular and multicellular levels. Here we show that the cultivation of cell populations on micropatterns with defined boundaries reveals intrinsic cell chirality that can be readily determined by image analysis of cell alignment and directional motion. By patterning 11 different types of cells on ring-shaped micropatterns of various sizes, we found that each cell type exhibited definite LR asymmetry (p value down to 10(-185)) that was different between normal and cancer cells of the same type, and not dependent on surface chemistry, protein coating, or the orientation of the gravitational field. Interestingly, drugs interfering with actin but not microtubule function reversed the LR asymmetry in some cell types. Our results show that micropatterned cell populations exhibit phenotype-specific LR asymmetry that is dependent on the functionality of the actin cytoskeleton. We propose that micropatterning could potentially be used as an effective in vitro tool to study the initiation of LR asymmetry in cell populations, to diagnose disease, and to study factors involved with birth defects in laterality.

In situ synthesis of twelve dialkyltartrate-boric acid complexes and two polyols-boric acid complexes and their applications as chiral ion-pair selectors in nonaqueous capillary electrophoresis.

PubMed

Wang, Li-Juan; Yang, Juan; Yang, Geng-Liang; Chen, Xing-Guo

2012-07-27

In this paper, twelve dialkyltartrate-boric acid complexes and two polyols-boric acid complexes were in situ synthesized by the reaction of different dialkyltartrates or polyols with boric acid in methanol containing triethylamine. All of the twelve dialkyltartrate-boric acid complexes were found to have relatively good chiral separation performance in nonaqueous capillary electrophoresis (NACE). Their chiral recognition effects in terms of both enantioselectivity (α) and resolution (R(s)) were similar when the number of carbon atoms was below six in the alkyl group of alcohol moiety. The dialkyltartrates containing alkyl groups of different structures but the same number of carbon atoms, i.e. one of straight chain and one of branched chain, also provided similar chiral recognition effects. Furthermore, it was demonstrated for the first time that two methanol insoluble polyols, D-mannitol and D-sorbitol, could react with boric acid to prepare chiral ion-pair selectors using methanol as the solvent medium. Copyright © 2012 Elsevier B.V. All rights reserved.

Field theoretic perspectives of the Wigner function formulation of the chiral magnetic effect

NASA Astrophysics Data System (ADS)

Wu, Yan; Hou, De-fu; Ren, Hai-cang

2017-11-01

We assess the applicability of the Wigner function formulation in its present form to the chiral magnetic effect and note some issues regarding the conservation and the consistency of the electric current in the presence of an inhomogeneous and time-dependent axial chemical potential. The problems are rooted in the ultraviolet divergence of the underlying field theory associated with the axial anomaly and can be fixed with the Pauli-Villars regularization of the Wigner function. The chiral magnetic current with a nonconstant axial chemical potential is calculated with the regularized Wigner function and the phenomenological implications are discussed.

Electromagnetic propulsion and separation by chirality of nanoparticles in liquids

NASA Astrophysics Data System (ADS)

Kirkinis, E.; Andreev, A. V.; Spivak, B.

2012-01-01

We introduce a new mechanism for the propulsion and separation by chirality of small ferromagnetic particles suspended in a liquid. Under the action of a uniform dc magnetic field H and an ac electric field E isomers with opposite chirality move in opposite directions. Such a mechanism could have a significant impact on a wide range of emerging technologies. The component of the chiral velocity that is odd in H is found to be proportional to the intrinsic orbital and spin angular momentum of the magnetized electrons. This effect arises because a ferromagnetic particle responds to the applied torque as a small gyroscope.

trans-2-Tritylcyclohexanol as a chiral auxiliary in permanganate-mediated oxidative cyclization of 2-methylenehept-5-enoates: application to the synthesis of trans-(+)-linalool oxide.

PubMed

Al Hazmi, Ali M; Sheikh, Nadeem S; Bataille, Carole J R; Al-Hadedi, Azzam A M; Watkin, Sam V; Luker, Tim J; Camp, Nicholas P; Brown, Richard C D

2014-10-03

The permanganate-mediated oxidative cyclization of a series of 2-methylenehept-5-eneoates bearing different chiral auxiliaries was investigated, leading to the discovery of trans-2-tritylcyclohexanol (TTC) as a highly effective chiral controller for the formation of the 2,5-substituted THF diol product with high diastereoselectivity (dr ∼97:3). Chiral resolution of (±)-TTC, prepared in one step from cyclohexene oxide, afforded (-)-(1S,2R)-TTC (er >99:1), which was applied to the synthesis of (+)-trans-(2S,5S)-linalool oxide.

Incomplete immunity to backscattering in chiral one-way photonic crystals.

PubMed

Cheng, Pi-Ju; Tien, Chung-Hao; Chang, Shu-Wei

2015-04-20

We show that the propagating modes in a strongly-guided chiral one-way photonic crystal are not backscattering-immune even though they are indeed insensitive to many kinds of scatters. Since these modes are not protected by the nonreciprocity, the backscattering does occur under certain circumstances. We use a perturbative method to derive criteria for the prominent backscattering in such chiral structures. From both our theory and numerical examinations, we find that the amount of backscattering critically depends on the symmetry of scatters. Additionally, for these chiral photonic modes, disturbances at the most intense parts of field profiles do not necessarily lead to the most effective backscattering.

Catalysis of partial chiral symmetry restoration by Δ matter

NASA Astrophysics Data System (ADS)

Takeda, Yusuke; Kim, Youngman; Harada, Masayasu

2018-06-01

We study the phase structure of dense hadronic matter including Δ (1232 ) as well as N (939 ) based on the parity partner structure, where the baryons have their chiral partners with a certain amount of chiral invariant masses. We show that, in symmetric matter, Δ enters into matter in the density region of about one to four times normal nuclear matter density, ρB˜1 -4 ρ0 . The onset density of Δ matter depends on the chiral invariant mass of Δ ,mΔ 0 : As mΔ 0 increases, the onset density becomes bigger. The stable Δ -nucleon matter is realized for ρB≳1.5 ρ0 , i.e., the phase transition from nuclear matter to Δ -nucleon matter is of first order for small mΔ 0, and it is of second order for large mΔ 0. We find that, associated with the phase transition, the chiral condensate changes very rapidly; i.e., the chiral symmetry restoration is accelerated by Δ matter. As a result of the accelerations, there appear N*(1535 ) and Δ (1700 ) , which are the chiral partners to N (939 ) and Δ (1232 ) , in high-density matter, signaling the partial chiral symmetry restoration. Furthermore, we find that complete chiral symmetry restoration itself is delayed by Δ matter. We also calculate the effective masses, pressure, and symmetry energy to study how the transition to Δ matter affects such physical quantities. We observe that the physical quantities change drastically at the transition density.

An implemented method of asymmetric transmission for arbitrary polarization base in multi-layered chiral meta-surface

NASA Astrophysics Data System (ADS)

Xiao, Zhong-yin; Zou, Huan-ling; Xu, Kai-Kai; Tang, Jing-yao

2018-03-01

Asymmetric transmission of linearly or circularly polarized waves is a well-established property not only for three-layered chiral structures but for multi-layered ones. Here we show a method which can simultaneously implement asymmetric transmission for arbitrary base vector polarized wave in multi-layered chiral meta-surface. We systematically study the implemented method based on a multi-layered chiral structure consisting of a y-shape, a half gammadion and an S-shape in the terahertz gap. A numerical simulation was carried out, followed by an explanation of the asymmetric transmission mechanism in these structures proposed in this work. The simulated results indicate that the multi-layered chiral structure can realize a maximum asymmetric transmission of 0.89 and 0.28 for circularly and linearly polarized waves, respectively, which exhibit magnitude improvement over previous chiral metamaterials. Specifically, the maximum asymmetric transmitted coefficient of the multi-layered chiral structure is insensitivity to the incident angles from 0° to 45° for circularly polarized components. Additionally, we also study the influence of structural parameters on the asymmetric transmission effect for both linearly and circularly polarized waves in detail.

INFLUENCE OF ENVIRONMENTAL CHANGES ON DEGRADATION OF CHIRAL POLLUTANTS IN SOILS

EPA Science Inventory

Numerous anthropogenic chemicals of environmental concern- including some phenoxy acid herbicides, organophosphorus insecticides, polychlorinated biphenyls, phthalates, freon substi- tutes and some DDT derivatives- are chiral. Their potential biological effects, such as toxicity,...

An Active Metamaterial Platform for Chiral Responsive Optoelectronics.

PubMed

Kang, Lei; Lan, Shoufeng; Cui, Yonghao; Rodrigues, Sean P; Liu, Yongmin; Werner, Douglas H; Cai, Wenshan

2015-08-05

Chiral-selective non-linear optics and optoelectronic signal generation are demonstrated in an electrically active photonic metamaterial. The metamaterial reveals significant chiroptical responses in both harmonic generation and the photon drag effect, correlated to the resonance behavior in the linear regime. The multifunctional chiral metamaterial with dual electrical and optical functionality enables transduction of chiroptical responses to electrical signals for integrated photonics. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Hydrodynamics with chiral anomaly and charge separation in relativistic heavy ion collisions

DOE PAGES

Yin, Yi; Liao, Jinfeng

2016-03-03

Matter with chiral fermions is microscopically described by theory with quantum anomaly and macroscopically described (at low energy) by anomalous hydrodynamics. For such systems in the presence of external magnetic field and chirality imbalance, a charge current is generated along the magnetic field direction ₋ a phenomenon known as the Chiral Magnetic Effect (CME). The quark- gluon plasma created in relativistic heavy ion collisions provides an (approximate) example, for which the CME predicts a charge separation perpendicular to the collisional reaction plane. Charge correlation measurements designed for the search of such signal have been done at RHIC and the LHCmore » for which the interpretations, however, remain unclear due to contamination by background effects that are collective flow driven, theoretically poorly constrained, and experimentally hard to separate. Using anomalous (and viscous) hydrodynamic simulations, we make a first attempt at quantifying contributions to observed charge correlations from both CME and background effects in one and same framework. We discuss the implications for the search of CME.« less

Status of the chiral magnetic effect and collisions of isobars

DOE PAGES

Koch, Volker; Schlichting, Soeren; Skokov, Vladimir; ...

2017-04-30

Here, we examine the current theoretical and experimental status of the chiral magnetic effect. We discuss possible future strategies for resolving uncertainties in interpretation including recommendations for theoretical work, recommendations for measurements based on data collected in the past five years, and recommendations for beam use in the coming years of RHIC. We then investigate the case for colliding nuclear isobars (nuclei with the same mass but different charge) and find the case compelling. We recommend that a program of nuclear isobar collisions to isolate the chiral magnetic effect from background sources be placed as a high priority item inmore » the strategy for completing the RHIC mission.« less

Chiral catalysts immobilized on achiral polymers: effect of the polymer support on the performance of the catalyst.

PubMed

Altava, Belén; Burguete, M Isabel; García-Verdugo, Eduardo; Luis, Santiago V

2018-04-23

Positive effects of the polymeric support on the performance of supported chiral catalysts, in terms of activity, stability and selectivity-enantioselectivity, have been reported when the support is properly selected and optimized opening the way to the design of more efficient catalytic systems.

Chiral Superstructure Mesophases of Achiral Bent-Shaped Molecules - Hierarchical Chirality Amplification and Physical Properties.

PubMed

Le, Khoa V; Takezoe, Hideo; Araoka, Fumito

2017-07-01

Chiral mesophases in achiral bent-shaped molecules have attracted particular attention since their discovery in the middle 1990s, not only because of their homochirality and polarity, but also due to their unique physical/physicochemical properties. Here, the most intriguing results in the studies of such symmetry-broken states, mainly helical-nanofilament (HNF) and dark-conglomerate (DC) phases, are reviewed. Firstly, basic information on the typical appearance and optical activity in these phases is introduced. In the following section, the formation of mesoscopic chiral superstructures in the HNF and DC phases is discussed in terms of hierarchical chirality. Nanoscale phase segregation in mixture systems and gelation ability in the HNF phase are also described. In addition, some other related chiral phases of bent-shaped molecules are shown. Recent attempts to control such mesoscopic chiral structure and the alignment/confinement of HNFs are also discussed, along with several examples of their fascinating advanced physical properties, i.e. huge enhancement of circular dichroism, electro- and photo-tunable optical activities, chirality-induced nonlinear optics (second-harmonic-generation circular difference and electrogyration effect), enhanced hydrophobicity through the dual-scale surface morphological modulation, and photoconductivity in the HNF/fullerene binary system. Future prospects from basic science and application viewpoints are also indicated in the concluding section. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Enantioselective column coupled electrophoresis employing large bore capillaries hyphenated with tandem mass spectrometry for ultra-trace determination of chiral compounds in complex real samples.

PubMed

Piešťanský, Juraj; Maráková, Katarína; Kovaľ, Marián; Havránek, Emil; Mikuš, Peter

2015-12-01

A new multidimensional analytical approach for the ultra-trace determination of target chiral compounds in unpretreated complex real samples was developed in this work. The proposed analytical system provided high orthogonality due to on-line combination of three different methods (separation mechanisms), i.e. (1) isotachophoresis (ITP), (2) chiral capillary zone electrophoresis (chiral CZE), and (3) triple quadrupole mass spectrometry (QqQ MS). The ITP step, performed in a large bore capillary (800 μm), was utilized for the effective sample pretreatment (preconcentration and matrix clean-up) in a large injection volume (1-10 μL) enabling to obtain as low as ca. 80 pg/mL limits of detection for the target enantiomers in urine matrices. In the chiral CZE step, the different chiral selectors (neutral, ionizable, and permanently charged cyclodextrins) and buffer systems were tested in terms of enantioselectivity and influence on the MS detection response. The performance parameters of the optimized ITP - chiral CZE-QqQ MS method were evaluated according to the FDA guidance for bioanalytical method validation. Successful validation and application (enantioselective monitoring of renally eliminated pheniramine and its metabolite in human urine) highlighted great potential of this chiral approach in advanced enantioselective biomedical applications. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Curvature bound from gravitational catalysis

NASA Astrophysics Data System (ADS)

Gies, Holger; Martini, Riccardo

2018-04-01

We determine bounds on the curvature of local patches of spacetime from the requirement of intact long-range chiral symmetry. The bounds arise from a scale-dependent analysis of gravitational catalysis and its influence on the effective potential for the chiral order parameter, as induced by fermionic fluctuations on a curved spacetime with local hyperbolic properties. The bound is expressed in terms of the local curvature scalar measured in units of a gauge-invariant coarse-graining scale. We argue that any effective field theory of quantum gravity obeying this curvature bound is safe from chiral symmetry breaking through gravitational catalysis and thus compatible with the simultaneous existence of chiral fermions in the low-energy spectrum. With increasing number of dimensions, the curvature bound in terms of the hyperbolic scale parameter becomes stronger. Applying the curvature bound to the asymptotic safety scenario for quantum gravity in four spacetime dimensions translates into bounds on the matter content of particle physics models.

Anomalous transport from holography. Part I

NASA Astrophysics Data System (ADS)

Bu, Yanyan; Lublinsky, Michael; Sharon, Amir

2016-11-01

We revisit the transport properties induced by the chiral anomaly in a charged plasma holographically dual to anomalous U(1) V ×U(1) A Maxwell theory in Schwarzschild-AdS5. Off-shell constitutive relations for vector and axial currents are derived using various approximations generalising most of known in the literature anomaly-induced phenomena and revealing some new ones. In a weak external field approximation, the constitutive relations have all-order derivatives resummed into six momenta-dependent transport co-efficient functions: the diffusion, the electric/magnetic conductivity, and three anomaly induced functions. The latter generalise the chiral magnetic and chiral separation effects. Nonlinear transport is studied assuming presence of constant background external fields. The chiral magnetic effect, including all order nonlinearity in magnetic field, is proven to be exact when the magnetic field is the only external field that is turned on. Non-linear corrections to the constitutive relations due to electric and axial external fields are computed.

Auxiliary field diffusion Monte Carlo calculations of light and medium-mass nuclei with local chiral interactions

NASA Astrophysics Data System (ADS)

Lonardoni, D.; Gandolfi, S.; Lynn, J. E.; Petrie, C.; Carlson, J.; Schmidt, K. E.; Schwenk, A.

2018-04-01

Quantum Monte Carlo methods have recently been employed to study properties of nuclei and infinite matter using local chiral effective-field-theory interactions. In this work, we present a detailed description of the auxiliary field diffusion Monte Carlo algorithm for nuclei in combination with local chiral two- and three-nucleon interactions up to next-to-next-to-leading order. We show results for the binding energy, charge radius, charge form factor, and Coulomb sum rule in nuclei with 3 ≤A ≤16 . Particular attention is devoted to the effect of different operator structures in the three-body force for different cutoffs. The outcomes suggest that local chiral interactions fit to few-body observables give a very good description of the ground-state properties of nuclei up to 16O, with the exception of one fit for the softer cutoff which predicts overbinding in larger nuclei.

Liquid crystal behavior induced assembling fabrication of conductive chiral MWCNTs@NCC nanopaper

NASA Astrophysics Data System (ADS)

Ren, Yumei; Wang, Tianjiao; Chen, Zhimin; Li, Jing; Tian, Qiuge; Yang, Hongxia; Xu, Qun

2016-11-01

The conductive chiral MWCNTs@NCC nanopapers obtained by the assembly of nanocrystalline cellulose liquid crystals (NCC LCs) host matrix along with one-dimensional (1-D) multi-walled carbon nanotubes (MWCNTs) have been studied in this work. Circular dichroism (CD) studies show strong signals stemming from the chiral nematic structure. Notably, the introduction of the MWCNTs has a pronounced effect on the chiral structure of the as-prepared nanopaper. Our experimental results indicate the multiple weak molecular interactions existing between MWCNTs and NCC are responsible for the effective dispersion and stabilization of MWCNTs. Moreover it also confirms the resulting nanopaper has an increased conductivity of 4.2 S/m at 1.96 wt% MWCNTs. So the co-assembly of the nanocomposite herein opens a gateway for preparing functional materials combining the photonic properties of the NCC LCs matrix with other building blocks that can supply other advantageous functions.

Synthesis of cellulose-2,3-bis(3,5-dimethylphenylcarbamate) in an ionic liquid and its chiral separation efficiency as stationary phase.

PubMed

Liu, Runqiang; Zhang, Yijun; Bai, Lianyang; Huang, Mingxian; Chen, Jun; Zhang, Yuping

2014-04-11

A chiral selector of cellulose-2,3-bis(3,5-dimethylphenylcarbamate) (CBDMPC) was synthesized by reacting 3,5-dimethylphenyl isocyanate with microcrystalline cellulose dissolved in an ionic liquid of 1-allyl-3-methyl-imidazolium chloride (AMIMCl). The obtained chiral selector was effectively characterized by infrared spectroscopy, elemental analysis and 1H NMR. The selector was reacted with 3-aminopropylsilanized silica gel and the CBDMPC bonded chiral stationary phase (CSP) was obtained. Chromatographic evaluation of the prepared CSPs was conducted by high performance liquid chromatographic (HPLC) and baseline separation of three typical fungicides including hexaconazole, metalaxyl and myclobutanil was achieved using n-hexane/isopropanol as the mobile phase with a flow rate 1.0 mL/min. Experimental results also showed that AMIMCl could be recycled easily and reused in the preparation of CSPs as an effective reaction media.

Synthesis of Cellulose-2,3-bis(3,5-dimethylphenylcarbamate) in an Ionic Liquid and Its Chiral Separation Efficiency as Stationary Phase

PubMed Central

Liu, Runqiang; Zhang, Yijun; Bai, Lianyang; Huang, Mingxian; Chen, Jun; Zhang, Yuping

2014-01-01

A chiral selector of cellulose-2,3-bis(3,5-dimethylphenylcarbamate) (CBDMPC) was synthesized by reacting 3,5-dimethylphenyl isocyanate with microcrystalline cellulose dissolved in an ionic liquid of 1-allyl-3-methyl-imidazolium chloride (AMIMCl). The obtained chiral selector was effectively characterized by infrared spectroscopy, elemental analysis and 1H NMR. The selector was reacted with 3-aminopropylsilanized silica gel and the CBDMPC bonded chiral stationary phase (CSP) was obtained. Chromatographic evaluation of the prepared CSPs was conducted by high performance liquid chromatographic (HPLC) and baseline separation of three typical fungicides including hexaconazole, metalaxyl and myclobutanil was achieved using n-hexane/isopropanol as the mobile phase with a flow rate 1.0 mL/min. Experimental results also showed that AMIMCl could be recycled easily and reused in the preparation of CSPs as an effective reaction media. PMID:24733066

Factorization of chiral string amplitudes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Yu-tin; Siegel, Warren; Yuan, Ellis Ye

We re-examine a closed-string model defined by altering the boundary conditions for one handedness of two-dimensional propagators in otherwise-standard string theory. We evaluate the amplitudes using Kawai-Lewellen-Tye factorization into open-string amplitudes. The only modification to standard string theory is effectively that the spacetime Minkowski metric changes overall sign in one open-string factor. This cancels all but a finite number of states: as found in earlier approaches, with enough supersymmetry (e.g., type II) the tree amplitudes reproduce those of the massless truncation of ordinary string theory. However, we now find for the other cases that additional fields, formerly thought to bemore » auxiliary, describe new spin-2 states at the two adjacent mass levels (tachyonic and tardyonic). The tachyon is always a ghost, but can be avoided in the heterotic case.« less

Factorization of chiral string amplitudes

DOE PAGES

Huang, Yu-tin; Siegel, Warren; Yuan, Ellis Ye

2016-09-16

We re-examine a closed-string model defined by altering the boundary conditions for one handedness of two-dimensional propagators in otherwise-standard string theory. We evaluate the amplitudes using Kawai-Lewellen-Tye factorization into open-string amplitudes. The only modification to standard string theory is effectively that the spacetime Minkowski metric changes overall sign in one open-string factor. This cancels all but a finite number of states: as found in earlier approaches, with enough supersymmetry (e.g., type II) the tree amplitudes reproduce those of the massless truncation of ordinary string theory. However, we now find for the other cases that additional fields, formerly thought to bemore » auxiliary, describe new spin-2 states at the two adjacent mass levels (tachyonic and tardyonic). The tachyon is always a ghost, but can be avoided in the heterotic case.« less

Description and Evaluation of Chiral Interactive Sites on Bonded Cyclodextrin Stationary Phases for Liquid Chromatography

NASA Astrophysics Data System (ADS)

Beesley, Thomas E.

Development of chiral separations has been essential to the drug discovery and development process. The solubility requirements for a number of methods and/or the mobile phase requirements for application of certain detection systems have opened up many opportunities for cyclodextrin-based CSPs for liquid chromatography. Even though a few chiral stationary phases cover a wide area of enantioselectivity, they do not meet the entire needs of the industry. Cyclodextrin phases offer some unique mechanisms and opportunities to resolve chiral separation problems especially in the aqueous reversed-phase and non-aqueous polar organic modes. This chapter addresses the need to understand the chiral stationary phase structure, the mechanisms at work, and the role mobile phase composition plays in driving those mechanisms to produce enantioselectivity. In addition, the development of certain derivatives has played an essential part in expanding that basic role for certain chiral separations. What these derivatives contribute in concert with the basic structure is a critical part of the understanding to the effective use of these phases. During this study it was determined that the role of steric hindrance has been vastly underestimated, both to the extent that it has occurred and to its effectiveness for obtaining enantioselectivity. References to the entire 20-year history of the cyclodextrin phase development and application literature up to this current date have been reviewed and incorporated.

Continuum limit of Bk from 2+1 flavor domain wall QCD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Soni, A.; T. Izubuchi, et al.

2011-07-01

We determine the neutral kaon mixing matrix element B{sub K} in the continuum limit with 2+1 flavors of domain wall fermions, using the Iwasaki gauge action at two different lattice spacings. These lattice fermions have near exact chiral symmetry and therefore avoid artificial lattice operator mixing. We introduce a significant improvement to the conventional nonperturbative renormalization (NPR) method in which the bare matrix elements are renormalized nonperturbatively in the regularization invariant momentum scheme (RI-MOM) and are then converted into the MS{sup -} scheme using continuum perturbation theory. In addition to RI-MOM, we introduce and implement four nonexceptional intermediate momentum schemesmore » that suppress infrared nonperturbative uncertainties in the renormalization procedure. We compute the conversion factors relating the matrix elements in this family of regularization invariant symmetric momentum schemes (RI-SMOM) and MS{sup -} at one-loop order. Comparison of the results obtained using these different intermediate schemes allows for a more reliable estimate of the unknown higher-order contributions and hence for a correspondingly more robust estimate of the systematic error. We also apply a recently proposed approach in which twisted boundary conditions are used to control the Symanzik expansion for off-shell vertex functions leading to a better control of the renormalization in the continuum limit. We control chiral extrapolation errors by considering both the next-to-leading order SU(2) chiral effective theory, and an analytic mass expansion. We obtain B{sub K}{sup MS{sup -}} (3 GeV) = 0.529(5){sub stat}(15){sub {chi}}(2){sub FV}(11){sub NPR}. This corresponds to B{sup -}{sub K}{sup RGI{sup -}} = 0.749(7){sub stat}(21){sub {chi}}(3){sub FV}(15){sub NPR}. Adding all sources of error in quadrature, we obtain B{sup -}{sub K}{sup RGI{sup -}} = 0.749(27){sub combined}, with an overall combined error of 3.6%.« less

Brilliant Sm, Eu, Tb, and Dy Chiral Lanthanide Complexes with Strong Circularly Polarized Luminescence

PubMed Central

Petoud, Stéphane; Muller, Gilles; Moore, Evan G.; Xu, Jide; Sokolnicki, Jurek; Riehl, James P.; Le, Uyen N.; Cohen, Seth M.; Raymond, Kenneth N.

2009-01-01

The synthesis, characterization, and luminescent behavior of trivalent Sm, Eu, Dy, and Tb complexes of two enantiomeric, octadentate, chiral, 2-hydroxyisophthalamide ligands are reported. These complexes are highly luminescent in solution. Functionalization of the achiral parent ligand with a chiral 1-phenylethylamine substituent on the open face of the complex in close proximity to the metal center yields complexes with strong circularly polarized luminescence (CPL) activity. This appears to be the first example of a system utilizing the same ligand architecture to sensitize four different lanthanide cations and display CPL activity. The luminescence dissymmetry factor, glum, recorded for the Eu(III) complex is one of the highest values reported, and this is the first time the CPL effect has been demonstrated for a Sm(III) complex with a chiral ligand. The combination of high luminescence intensity with CPL activity should enable new bioanalytical applications of macromolecules in chiral environments. PMID:17199285

Interactions between pyrazole derived enantiomers and Chiralcel OJ: Prediction of enantiomer absolute configurations and elution order by molecular dynamics simulations.

PubMed

Hu, Guixiang; Huang, Meilan; Luo, Chengcai; Wang, Qi; Zou, Jian-Wei

2016-05-01

The separation of enantiomers and confirmation of their absolute configurations is significant in the development of chiral drugs. The interactions between the enantiomers of chiral pyrazole derivative and polysaccharide-based chiral stationary phase cellulose tris(4-methylbenzoate) (Chiralcel OJ) in seven solvents and under different temperature were studied using molecular dynamics simulations. The results show that solvent effect has remarkable influence on the interactions. Structure analysis discloses that the different interactions between two isomers and chiral stationary phase are dependent on the nature of solvents, which may invert the elution order. The computational method in the present study can be used to predict the elution order and the absolute configurations of enantiomers in HPLC separations and therefore would be valuable in development of chiral drugs. Copyright © 2016 Elsevier Inc. All rights reserved.

Lewis base catalyzed aldol additions of chiral trichlorosilyl enolates and silyl enol ethers.

PubMed

Denmark, Scott E; Fujimori, Shinji; Pham, Son M

2005-12-23

[structures: see text] The consequences of double diastereodifferentiation in chiral Lewis base catalyzed aldol additions using chiral enoxysilanes derived from lactate, 3-hydroxyisobutyrate, and 3-hydroxybutyrate have been investigated. Trichlorosilyl enolates derived from the chiral methyl and ethyl ketones were subjected to aldolization in the presence of phosphoramides, and the intrinsic selectivity of these enolates and the external stereoinduction from chiral catalyst were studied. In the reactions with the lactate derived enolate, the strong internal stereoinduction dominated the stereochemical outcome of the aldol addition. For the 3-hydroxyisobutyrate- and 3-hydroxybutyrate derived enolates, the catalyst-controlled diastereoselectivities were observed, and the resident stereogenic centers exerted marginal influence. The corresponding trimethylsilyl enol ethers were employed in SiCl4/bisphosphoramide catalyzed aldol additions, and the effect of double diastereodifferentiation was also investigated. The overall diastereoselection of the process was again controlled by the strong external influence of the catalyst.

Effect of chiral symmetry on chaotic scattering from Majorana zero modes.

PubMed

Schomerus, H; Marciani, M; Beenakker, C W J

2015-04-24

In many of the experimental systems that may host Majorana zero modes, a so-called chiral symmetry exists that protects overlapping zero modes from splitting up. This symmetry is operative in a superconducting nanowire that is narrower than the spin-orbit scattering length, and at the Dirac point of a superconductor-topological insulator heterostructure. Here we show that chiral symmetry strongly modifies the dynamical and spectral properties of a chaotic scatterer, even if it binds only a single zero mode. These properties are quantified by the Wigner-Smith time-delay matrix Q=-iℏS^{†}dS/dE, the Hermitian energy derivative of the scattering matrix, related to the density of states by ρ=(2πℏ)^{-1}TrQ. We compute the probability distribution of Q and ρ, dependent on the number ν of Majorana zero modes, in the chiral ensembles of random-matrix theory. Chiral symmetry is essential for a significant ν dependence.

How tetraquarks can generate a second chiral phase transition

DOE PAGES

Pisarski, Robert D.; Skokov, Vladimir V.

2016-09-09

We consider how tetraquarks can affect the chiral phase transition in theories like QCD, with light quarks coupled to three colors. For two flavors the tetraquark field is an isosinglet, and its effect is minimal. For three flavors, however, the tetraquark field transforms in the same representation of the chiral symmetry group as the usual chiral order parameter, and so for very light quarks there may be two chiral phase transitions, which are both of first order. In QCD, results from the lattice indicate that any transition from the tetraquark condensate is a smooth crossover. In the plane of temperature,more » T, and quark chemical potential, μ, though, a crossover line for the tetraquark condensate is naturally related to the transition line for color superconductivity. For four flavors we suggest that a triquark field, antisymmetric in both flavor and color, combine to form hexaquarks.« less

Leading order relativistic chiral nucleon-nucleon interaction

NASA Astrophysics Data System (ADS)

Ren, Xiu-Lei; Li, Kai-Wen; Geng, Li-Sheng; Long, Bingwei; Ring, Peter; Meng, Jie

2018-01-01

Motivated by the successes of relativistic theories in studies of atomic/molecular and nuclear systems and the need for a relativistic chiral force in relativistic nuclear structure studies, we explore a new relativistic scheme to construct the nucleon-nucleon interaction in the framework of covariant chiral effective field theory. The chiral interaction is formulated up to leading order with covariant power counting and a Lorentz invariant chiral Lagrangian. We find that the relativistic scheme induces all six spin operators needed to describe the nuclear force. A detailed investigation of the partial wave potentials shows a better description of the {}1S0 and {}3P0 phase shifts than the leading order Weinberg approach, and similar to that of the next-to-leading order Weinberg approach. For the other partial waves with angular momenta J≥slant 1, the relativistic results are almost the same as their leading order non-relativistic counterparts. )

[Topological models of retention index of thin-layer chromatogram for chiral organic acids].

PubMed

Li, Mingjian; Wang, Yuxiao; Feng, Hui; Feng, Changjun

2014-03-01

On the basis of Kier's molecular connectivity indices and conjugated matrix, novel molecular connectivity indices ((m) G(t)(v)) were defined and calculated for 18 chiral hydroxyl acids and amino acids. The chiral connectivity indices ((m)C(t)(v)) were introduced by extending (m)G(t)(v): (m)C(t)(v) = (m)G(t)(v) x w(j), where w(j) is the chiral index. The quantitative structure-retention index relationship (QSRR) between the retention index (R(M)) of thin-layer chromatogram for the chiral organic acids and (m)C(t)(v) was studied by multivariate statistical regression. By leaps-and-bounds regression analysis, the best four-parameter QSRR model was set up, and the traditional correlation coefficient (R2) and the cross-validation correlation coefficient (Q2) of leave-one-out (LOO) were 0.973 and 0.950, respectively. The results demonstrated that the model was highly reliable and had good predictive ability from the point of view of statistics. From the four parameters (0C(p)(v), 2C(p)(v), C(ch),(v), 5C(p)(v)) of the model, it is known that the dominant influence factors of the retention index were the molecular structure characteristics of two-dimensional and the space factors: the chiral characteristics, the flexibility and the puckered degree of molecules for the chiral organic acids. The results showed that the new parameter mC(t)(v) had good rationality and efficiency for the retention indices of the chiral organic acids. Therefore, an effective method was provided to predict the retention indices of the chiral organic acids.

Chiral symmetry and the nucleon-nucleon interaction

DOE PAGES

Machleidt, Ruprecht

2016-04-20

We review how nuclear forces emerge from low-energy quantum chromodynamics (QCD) via chiral effective field theory (EFT). During the past two decades, this approach has evolved into a powerful tool to derive nuclear two- and many-body forces in a systematic and model-independent way. We then focus on the nucleon-nucleon (NN) interaction and show in detail how, governed by chiral symmetry, the long- and intermediate-range of the NN potential builds up order by order. We proceed up to sixth order in small momenta, where convergence is achieved. Lastly, the final result allows for a full assessment of the validity of themore » chiral EFT approach to the NN interaction.« less

A Reflection on the Fate of Chiral 1,2,4-Triazole Fungicides in Biological Systems

EPA Science Inventory

In biological systems, stereoisomers of chiral compounds can exhibit significantly different pharmacokinetics (absorption, distribution, metabolism, and elimination) and pharmacodynamics (physiological effects). Pharmacokinetic processes (i.e., what the body does to the chemical)...

Anomalous effects of dense matter under rotation

NASA Astrophysics Data System (ADS)

Huang, Xu-Guang; Nishimura, Kentaro; Yamamoto, Naoki

2018-02-01

We study the anomaly induced effects of dense baryonic matter under rotation. We derive the anomalous terms that account for the chiral vortical effect in the low-energy effective theory for light Nambu-Goldstone modes. The anomalous terms lead to new physical consequences, such as the anomalous Hall energy current and spontaneous generation of angular momentum in a magnetic field (or spontaneous magnetization by rotation). In particular, we show that, due to the presence of such anomalous terms, the ground state of the quantum chromodynamics (QCD) under sufficiently fast rotation becomes the "chiral soliton lattice" of neutral pions that has lower energy than the QCD vacuum and nuclear matter. We briefly discuss the possible realization of the chiral soliton lattice induced by a fast rotation in noncentral heavy ion collisions.

Nuclear axial currents in chiral effective field theory

DOE PAGES

Baroni, Alessandro; Girlanda, Luca; Pastore, Saori; ...

2016-01-11

Two-nucleon axial charge and current operators are derived in chiral effective field theory up to one loop. The derivation is based on time-ordered perturbation theory and accounts for cancellations between the contributions of irreducible diagrams and the contributions owing to nonstatic corrections from energy denominators of reducible diagrams. Ultraviolet divergencies associated with the loop corrections are isolated in dimensional regularization. The resulting axial current is finite and conserved in the chiral limit, while the axial charge requires renormalization. As a result, a complete set of contact terms for the axial charge up to the relevant order in the power countingmore » is constructed.« less

The Chiral Separation Effect in quenched finite-density QCD

NASA Astrophysics Data System (ADS)

Puhr, Matthias; Buividovich, Pavel

2018-03-01

We present results of a study of the Chiral Separation Effect (CSE) in quenched finite-density QCD. Using a recently developed numerical method we calculate the conserved axial current for exactly chiral overlap fermions at finite density for the first time. We compute the anomalous transport coeffcient for the CSE in the confining and deconfining phase and investigate possible deviations from the universal value. In both phases we find that non-perturbative corrections to the CSE are absent and we reproduce the universal value for the transport coeffcient within small statistical errors. Our results suggest that the CSE can be used to determine the renormalisation factor of the axial current.

Effects of the regularization on the restoration of chiral and axial symmetries

NASA Astrophysics Data System (ADS)

Costa, P.; Ruivo, M. C.; de Sousa, C. A.

2008-05-01

The effects of a type of regularization for finite temperatures on the restoration of chiral and axial symmetries are investigated within the SU(3) Nambu-Jona-Lasinio model. The regularization consists in using an infinite cutoff in the integrals that are convergent at finite temperature, a procedure that allows one to take into account the effects of high momentum quarks at high temperatures. It is found that the critical temperature for the phase transition is closer to lattice results than the one obtained with the conventional regularization, and the restoration of chiral and axial symmetries, signaled by the behavior of several observables, occurs simultaneously and at a higher temperature. The restoration of the axial symmetry appears as a natural consequence of the full recovering of the chiral symmetry that was dynamically broken. By using an additional ansatz that simulates instanton suppression effects, by means of a convenient temperature dependence of the anomaly coefficient, we found that the restoration of U(2) symmetry is shifted to lower values, but the dominant effect at high temperatures comes from the new regularization that enhances the decrease of quark condensates, especially in the strange sector.

Chirality in Magnetic Multilayers Probed by the Symmetry and the Amplitude of Dichroism in X-Ray Resonant Magnetic Scattering

NASA Astrophysics Data System (ADS)

Chauleau, Jean-Yves; Legrand, William; Reyren, Nicolas; Maccariello, Davide; Collin, Sophie; Popescu, Horia; Bouzehouane, Karim; Cros, Vincent; Jaouen, Nicolas; Fert, Albert

2018-01-01

Chirality in condensed matter has recently become a topic of the utmost importance because of its significant role in the understanding and mastering of a large variety of new fundamental physical mechanisms. Versatile experimental approaches, capable to reveal easily the exact winding of order parameters, are therefore essential. Here we report x-ray resonant magnetic scattering as a straightforward tool to reveal directly the properties of chiral magnetic systems. We show that it can straightforwardly and unambiguously determine the main characteristics of chiral magnetic distributions: i.e., its chiral nature, the quantitative winding sense (clockwise or counterclockwise), and its type, i.e., Néel [cycloidal] or Bloch [helical]. This method is model independent, does not require a priori knowledge of the magnetic parameters, and can be applied to any system with magnetic domains ranging from a few nanometers (wavelength limited) to several microns. By using prototypical multilayers with tailored magnetic chiralities driven by spin-orbit-related effects at Co |Pt interfaces, we illustrate the strength of this method.

Influence of optical activity on rogue waves propagating in chiral optical fibers.

PubMed

Temgoua, D D Estelle; Kofane, T C

2016-06-01

We derive the nonlinear Schrödinger (NLS) equation in chiral optical fiber with right- and left-hand nonlinear polarization. We use the similarity transformation to reduce the generalized chiral NLS equation to the higher-order integrable Hirota equation. We present the first- and second-order rational solutions of the chiral NLS equation with variable and constant coefficients, based on the modified Darboux transformation method. For some specific set of parameters, the features of chiral optical rogue waves are analyzed from analytical results, showing the influence of optical activity on waves. We also generate the exact solutions of the two-component coupled nonlinear Schrödinger equations, which describe optical activity effects on the propagation of rogue waves, and their properties in linear and nonlinear coupling cases are investigated. The condition of modulation instability of the background reveals the existence of vector rogue waves and the number of stable and unstable branches. Controllability of chiral optical rogue waves is examined by numerical simulations and may bring potential applications in optical fibers and in many other physical systems.

Formation of Coaxial Nanocables with Amplified Supramolecular Chirality through an Interaction between Carbon Nanotubes and a Chiral π-Gelator.

PubMed

Vedhanarayanan, Balaraman; Nair, Vishnu S; Nair, Vijayakumar C; Ajayaghosh, Ayyappanpillai

2016-08-22

In an attempt to gather experimental evidence for the influence of carbon allotropes on supramolecular chirality, we found that carbon nanotubes (CNTs) facilitate amplification of the molecular chirality of a π-gelator (MC-OPV) to supramolecular helicity at a concentration much lower than that required for intermolecular interaction. For example, at a concentration 1.8×10(-4)  m, MC-OPV did not exhibit a CD signal; however, the addition of 0-0.6 mg of SWNTs resulted in amplified chirality as evident from the CD spectrum. Surprisingly, AFM analysis revealed the formation of thick helical fibers with a width of more than 100 nm. High-resolution TEM analysis and solid-state UV/Vis/NIR spectroscopy revealed that the thick helical fibers were cylindrical cables composed of individually wrapped and coaxially aligned SWNTs. Such an impressive effect of CNTs on supramolecular chirality and cylindrical-cable formation has not been reported previously. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The dynamics of supertranslations and superrotations in 2  +  1 dimensions

NASA Astrophysics Data System (ADS)

Carlip, S.

2018-01-01

Supertranslations, and at least in 2  +  1 dimensions superrotations, are asymptotic symmetries of the metric in asymptotically flat spacetimes. They are not, however, symmetries of the boundary term of the Einstein–Hilbert action, which therefore induces an action for the Goldstone-like fields that parametrize these symmetries. I show that in 2  +  1 dimensions, this action is closely related to a chiral Liouville action, as well as the ‘Schwarzian’ action that appears in two-dimensional near-AdS physics.

Chiral transport along magnetic domain walls in the quantum anomalous Hall effect

DOE PAGES

Rosen, Ilan T.; Fox, Eli J.; Kou, Xufeng; ...

2017-12-01

The recent prediction, and subsequent discovery, of the quantum anomalous Hall (QAH) effect in thin films of the three-dimensional ferromagnetic topological insulator (MTI) (Crmore » $$_y$$Bi$$_x$$Sb$$_{1-x-y}$$)$$_2$$Te$$_3$$ has opened new possibilities for chiral-edge-state-based devices in zero external magnetic field. Like the $$\

EFFECTS OF PCB 84 ATROPISOMERS ON [3H]-PHORBOL ESTER BINDING IN RAT CEREBELLAR GRANULE CELLS AND 45CA2+-UPTAKE IN RAT CEREBELLUM.

EPA Science Inventory

There is evidence that Polychlorinated biphenyl (PCB) congeners with ortho substituents have potential to cause neurotoxicity. Many PCB congeners implicated in these neurotoxic effects are chiral. It is currently unknown if the enantiomers of a chiral PCB congeners have differe...

Elasticity-driven partial demixing in cholesteric liquid crystal films.

PubMed

Schmidtke, Jürgen; Coles, Harry J

2009-07-01

We discuss the partial demixing of a chiral nematic mixture of a chiral and an achiral compound, induced by inhomogeneous confinement between substrates. While the effect is tiny in low molar mass mixtures, it is predicted to be noticeable in polymeric systems. The potential of the effect for improving performance of liquid crystal based photonic devices is discussed.

Light-front representation of chiral dynamics in peripheral transverse densities

DOE PAGES

Granados, Carlos G.; Weiss, Christian

2015-07-31

The nucleon's electromagnetic form factors are expressed in terms of the transverse densities of charge and magnetization at fixed light-front time. At peripheral transverse distances b = O(M_pi^{-1}) the densities are governed by chiral dynamics and can be calculated model-independently using chiral effective field theory (EFT). We represent the leading-order chiral EFT results for the peripheral transverse densities as overlap integrals of chiral light-front wave functions, describing the transition of the initial nucleon to soft pion-nucleon intermediate states and back. The new representation (a) explains the parametric order of the peripheral transverse densities; (b) establishes an inequality between the spin-independentmore » and -dependent densities; (c) exposes the role of pion orbital angular momentum in chiral dynamics; (d) reveals a large left-right asymmetry of the current in a transversely polarized nucleon and suggests a simple interpretation. The light-front representation enables a first-quantized, quantum-mechanical view of chiral dynamics that is fully relativistic and exactly equivalent to the second-quantized, field-theoretical formulation. It relates the charge and magnetization densities measured in low-energy elastic scattering to the generalized parton distributions probed in peripheral high-energy scattering processes. The method can be applied to nucleon form factors of other operators, e.g. the energy-momentum tensor.« less

Fabrication of Supramolecular Chirality from Achiral Molecules at the Liquid/Liquid Interface Studied by Second Harmonic Generation.

PubMed

Lin, Lu; Zhang, Zhen; Guo, Yuan; Liu, Minghua

2018-01-09

We present the investigation into the supramolecular chirality of 5-octadecyloxy-2-(2-pyridylazo)phenol (PARC18) at water/1,2-dichloroethane interface by second harmonic generation (SHG). We observe that PARC18 molecules form supramolecular chirality through self-assembly at the liquid/liquid interface although they are achiral molecules. The bulk concentration of PARC18 in the organic phase has profound effects on the supramolecular chirality. By increasing bulk concentration, the enantiomeric excess at the interface first grows and then decreases until it eventually vanishes. Further analysis reveals that the enantiomeric excess is determined by the twist angle of PARC18 molecules at the interface rather than their orientational angle. At lower and higher bulk concentrations, the average twist angle of PARC18 molecules approaches zero, and the assemblies are achiral; whereas at medium bulk concentrations, the average twist angle is nonzero, so that the assemblies show supramolecular chirality. We also estimate the coverage of PARC18 molecules at the interface versus the bulk concentration and fit it to Langmuir adsorption model. The result indicates that PARC18 assemblies show strongest supramolecular chirality in a half-full monolayer. These findings highlight the opportunities for precise control of supramolecular chirality at liquid/liquid interfaces by manipulating the bulk concentration.

Circularly Polarized Light with Sense and Wavelengths To Regulate Azobenzene Supramolecular Chirality in Optofluidic Medium.

PubMed

Wang, Laibing; Yin, Lu; Zhang, Wei; Zhu, Xiulin; Fujiki, Michiya

2017-09-20

Circularly polarized light (CPL) as a massless physical force causes absolute asymmetric photosynthesis, photodestruction, and photoresolution. CPL handedness has long been believed to be the determining factor in the resulting product's chirality. However, product chirality as a function of the CPL handedness, irradiation wavelength, and irradiation time has not yet been studied systematically. Herein, we investigate this topic using achiral polymethacrylate carrying achiral azobenzene as micrometer-size aggregates in an optofluidic medium with a tuned refractive index. Azobenzene chirality with a high degree of dissymmetry ratio (±1.3 × 10 -2 at 313 nm) was generated, inverted, and switched in multiple cycles by irradiation with monochromatic incoherent CPL (313, 365, 405, and 436 nm) for 20 s using a weak incoherent light source (≈ 30 μW·cm -2 ). Moreover, the optical activity was retained for over 1 week in the dark. Photoinduced chirality was swapped by the irradiating wavelength, regardless of whether the CPL sense was the same. This scenario is similar to the so-called Cotton effect, which was first described in 1895. The tandem choice of both CPL sense and its wavelength was crucial for azobenzene chirality. Our experimental proof and theoretical simulation should provide new insight into the chirality of CPL-controlled molecules, supramolecules, and polymers.

Chiral anomaly and longitudinal magnetotransport in type-II Weyl semimetals

NASA Astrophysics Data System (ADS)

Sharma, Girish; Goswami, Pallab; Tewari, Sumanta

2017-07-01

In the presence of parallel electric and magnetic fields, the violation of a separate number conservation laws for the three-dimensional left- and right-handed Weyl fermions is known as the chiral anomaly. The recent discovery of Weyl and Dirac semimetals has paved the way for experimentally testing the effects of chiral anomaly via magnetotransport measurements, since chiral anomaly can lead to negative longitudinal magnetoresistance (LMR) while the transverse magnetoresistance remains positive. More recently, a type-II Weyl semimetal (WSM) phase has been proposed, where the nodal points possess a finite density of states due to the touching between electron and hole pockets. It has been suggested that the main difference between the two types of WSMs (type I and type II) is that in the latter, chiral-anomaly-induced negative LMR (positive longitudinal magnetoconductance) is strongly anisotropic, vanishing when the applied magnetic field is perpendicular to the direction of tilt of Weyl fermion cones in a type-II WSM. We analyze chiral anomaly in a type-II WSM in a quasiclassical Boltzmann framework, and find that the chiral-anomaly-induced positive longitudinal magnetoconductivity is present along any arbitrary direction. Thus, our results are pertinent for uncovering transport signatures of type-II WSMs in different candidate materials.

Competitive chiral induction in a 2D molecular assembly: Intrinsic chirality versus coadsorber-induced chirality.

PubMed

Chen, Ting; Li, Shu-Ying; Wang, Dong; Wan, Li-Jun

2017-11-01

Noncovalently introducing stereogenic information is a promising approach to embed chirality in achiral molecular systems. However, the interplay of the noncovalently introduced chirality with the intrinsic chirality of molecules or molecular aggregations has rarely been addressed. We report a competitive chiral expression of the noncovalent interaction-mediated chirality induction and the intrinsic stereogenic center-controlled chirality induction in a two-dimensional (2D) molecular assembly at the liquid/solid interface. Two enantiomorphous honeycomb networks are formed by the coassembly of an achiral 5-(benzyloxy)isophthalic acid (BIC) derivative and 1-octanol at the liquid/solid interface. The preferential formation of the globally homochiral assembly can be achieved either by using the chiral analog of 1-octanol, ( S )-6-methyl-1-octanol, as a chiral coadsorber to induce chirality to the BIC assembly via noncovalent hydrogen bonding or by covalently linking a chiral center in the side chain of BIC. Both the chiral coadsorber and the intrinsically chiral BIC derivative can act as a chiral seeds to induce a preferred handedness in the assembly of the achiral BIC derivatives. Furthermore, the noncovalent interaction-mediated chirality induction can restrain or even overrule the manifestation of the intrinsic chirality of the BIC molecule and dominate the handedness of the 2D molecular coassembly. This study provides insight into the interplay of intrinsically chiral centers and external chiral coadsorbers in the chiral induction, transfer, and amplification processes of 2D molecular assembly.

Competitive chiral induction in a 2D molecular assembly: Intrinsic chirality versus coadsorber-induced chirality

PubMed Central

Chen, Ting; Li, Shu-Ying; Wang, Dong; Wan, Li-Jun

2017-01-01

Noncovalently introducing stereogenic information is a promising approach to embed chirality in achiral molecular systems. However, the interplay of the noncovalently introduced chirality with the intrinsic chirality of molecules or molecular aggregations has rarely been addressed. We report a competitive chiral expression of the noncovalent interaction–mediated chirality induction and the intrinsic stereogenic center–controlled chirality induction in a two-dimensional (2D) molecular assembly at the liquid/solid interface. Two enantiomorphous honeycomb networks are formed by the coassembly of an achiral 5-(benzyloxy)isophthalic acid (BIC) derivative and 1-octanol at the liquid/solid interface. The preferential formation of the globally homochiral assembly can be achieved either by using the chiral analog of 1-octanol, (S)-6-methyl-1-octanol, as a chiral coadsorber to induce chirality to the BIC assembly via noncovalent hydrogen bonding or by covalently linking a chiral center in the side chain of BIC. Both the chiral coadsorber and the intrinsically chiral BIC derivative can act as a chiral seeds to induce a preferred handedness in the assembly of the achiral BIC derivatives. Furthermore, the noncovalent interaction–mediated chirality induction can restrain or even overrule the manifestation of the intrinsic chirality of the BIC molecule and dominate the handedness of the 2D molecular coassembly. This study provides insight into the interplay of intrinsically chiral centers and external chiral coadsorbers in the chiral induction, transfer, and amplification processes of 2D molecular assembly. PMID:29119137

Covariant and 3 + 1 Equations for Dynamo-Chiral General Relativistic Magnetohydrodynamics

NASA Astrophysics Data System (ADS)

Del Zanna, L.; Bucciantini, N.

2018-06-01

The exponential amplification of initial seed magnetic fields in relativistic plasmas is a very important topic in astrophysics, from the conditions in the early Universe to the interior of neutron stars. While dynamo action in a turbulent plasma is often invoked, in the last years a novel mechanism of quantum origin has gained increasingly more attention, namely the Chiral Magnetic Effect (CME). This has been recognized in semi-metals and it is most likely at work in the quark-gluon plasma formed in heavy-ion collision experiments, where the highest magnetic fields in nature, up to B ˜ 1018 G, are produced. This effect is expected to survive even at large hydrodynamical/MHD scales and it is based on the chiral anomaly due to an imbalance between left- and right-handed relativistic fermions in the constituent plasma. Such imbalance leads to an electric current parallel to an external magnetic field, which is precisely the same mechanism of an α-dynamo action in classical MHD. Here we extend the close parallelism between the chiral and the dynamo effects to relativistic plasmas and we propose a unified, fully covariant formulation of the generalized Ohm's law. Moreover, we derive for the first time the 3 + 1 general relativistic MHD equations for a chiral plasma both in flat and curved spacetimes, in view of numerical investigation of the CME in compact objects, especially magnetars, or of the interplay among the non-ideal magnetic effects of dynamo, the CME and reconnection.

Spontaneous Hall effect in a chiral p-wave superconductor

NASA Astrophysics Data System (ADS)

Furusaki, Akira; Matsumoto, Masashige; Sigrist, Manfred

2001-08-01

In a chiral superconductor with broken time-reversal symmetry a ``spontaneous Hall effect'' may be observed. We analyze this phenomenon by taking into account the surface properties of a chiral superconductor. We identify two main contributions to the spontaneous Hall effect. One contribution originates from the Bernoulli (or Lorentz) force due to spontaneous currents running along the surfaces of the superconductor. The other contribution has a topological origin and is related to the intrinsic angular momentum of Cooper pairs. The latter can be described in terms of a Chern-Simons-like term in the low-energy field theory of the superconductor and has some similarities with the quantum Hall effect. The spontaneous Hall effect in a chiral superconductor is, however, nonuniversal. Our analysis is based on three approaches to the problem: a self-consistent solution of the Bogoliubov-de Gennes equation, a generalized Ginzburg-Landau theory, and a hydrodynamic formulation. All three methods consistently lead to the same conclusion that the spontaneous Hall resistance of a two-dimensional superconducting Hall bar is of order h/(ekFλ)2, where kF is the Fermi wave vector and λ is the London penetration depth; the Hall resistance is substantially suppressed from a quantum unit of resistance. Experimental issues in measuring this effect are briefly discussed.

Manipulating Light and Matter with Photonic Structures: Numerical Investigations on Photonic Crystals and Optical Forces

NASA Astrophysics Data System (ADS)

Zhang, Peng

The highly developed nano-fabrication techniques allow light to be modulated with photonic structures in a more intensive way. These photonic structures involve photonic crystals, metals supporting surface plasmon polaritons, metamaterials, etc. In this thesis work, three different ways for light manipulation are numerically investigated. First, the light propagation is modulated using a photonic crystal with Dirac cones. It is demonstrated that the zero-index behavior of this photonic crystal which happens for normal incident waves, is lost at oblique incidence. A new method combining complex-k band calculations and absorbing boundary conditions for Bloch modes is developed to analyze the Bloch mode interaction in details. Second, the mechanic states of graphene are modulated through the optical gradient force. This force is induced by the coupled surface plasmons on the double graphene sheets and is greatly enhanced in comparison to the regular waveguides. By applying different strengths of forces in accordance to the input power, the mechanic state transition is made possible, accompanied by an abrupt change in the transmission and reflection spectra. Third, the helicity/chirality of light is studied to modulate the lateral force on a small particle. A left-hand material slab which supports coherent TE ad TM plasmons simultaneously is introduced. By mixing the TE and TM surface plasmons with different relative phases, the lateral force on a chiral particle can be changed, which will be beneficial for chiral particle sorting.

Gelation induced supramolecular chirality: chirality transfer, amplification and application.

PubMed

Duan, Pengfei; Cao, Hai; Zhang, Li; Liu, Minghua

2014-08-14

Supramolecular chirality defines chirality at the supramolecular level, and is generated from the spatial arrangement of component molecules assembling through non-covalent interactions such as hydrogen bonding, van der Waals interactions, π-π stacking, hydrophobic interactions and so on. During the formation of low molecular weight gels (LMWGs), one kind of fascinating soft material, one frequently encounters the phenomenon of chirality as well as chiral nanostructures, either from chiral gelators or even achiral gelators. A view of gelation-induced supramolecular chirality will be very helpful to understand the self-assembly process of the gelator molecules as well as the chiral structures, the regulation of the chirality in the gels and the development of the "smart" chiral materials such as chiroptical devices, catalysts and chiral sensors. It necessitates fundamental understanding of chirality transfer and amplification in these supramolecular systems. In this review, recent progress in gelation-induced supramolecular chirality is discussed.

Impact of pyrrolidine-bispyrrole DNA minor groove binding agents and chirality on global proteomic profile in Escherichia Coli.

PubMed

Yang, Ya-Ting; Lin, Chun-Yu; Jeng, Jingyueh; Ong, Chi-Wi

2013-05-23

There is great interest in the design of small molecules that selectively target minor grooves of duplex DNA for controlling specific gene expression implicated in a disease. The design of chiral small molecules for rational drug design has attracted increasing attention due to the chirality of DNA. Yet, there is limited research on the chirality effect of minor groove binders on DNA interaction, especially at the protein expression level. This paper is an attempt to illustrate that DNA binding affinity might not provide a full picture on the biological activities. Drug interacting at the genomic level can be translated to the proteomic level. Here we have illustrated that although the chiral bispyrrole-pyrrolidine-oligoamides, PySSPy and PyRSPy, showed low binding affinity to DNA, their influence at the proteomic level is significant. More importantly, the chirality also plays a role. Two-dimensional proteomic profile to identify the differentially expressed protein in Escherichia coli DH5α (E coli DH5α) were investigated. E coli DH5α incubated with the chiral PySSPy and PyRSPy, diastereomeric at the pyrrolidine ring, showed differential expression of eighteen proteins as observed through two dimensional proteomic profiling. These eighteen proteins identified by MALDI_TOF/TOF MS include antioxidant defense, DNA protection, protein synthesis, chaperone, and stress response proteins. No statistically significant toxicity was observed at the tested drug concentrations as measured via MTT assay. The current results showed that the chiral PySSPy and PyRSPy impact on the proteomic profiling of E coli DH5α, implicating the importance of drug chirality on biological activities at the molecular level.

Conformational arm-wrestling: battles for stereochemical control in benzamides bearing matched and mismatched chiral 2- and 6-substituents.

PubMed

Clayden, Jonathan; Foricher, Yann J Y; Helliwell, Madeleine; Johnson, Paul; Mitjans, David; Vinader, Victoria

2006-02-07

The orientation of a tertiary amide group adjacent to an aromatic ring may be governed by the stereochemistry of an adjacent chiral substituent. With a chiral substituent in both ortho positions, matched/mismatched pairs of isomers result. Evidence for matched stereochemistry is provided by the clean NMR spectra of single conformers, while mismatching gives poor or unexpected selectivities in the formation of chiral substituents, or mixtures of amide conformers. Attempts to use the match-mismatch effect to select for racemic pairs of enantiomeric substituents, and hence develop a "racemate-sequestering" reagent, are described, along with the use of "matching" to scavenge a single enantiomer of a diamine from material of incomplete enantiomeric purity.

Piezoelectric Characteristics of Chiral Polymer Composite Films Obtained under Strong Magnetic Field

NASA Astrophysics Data System (ADS)

Nakiri, Takuo; Okuno, Masaki; Maki, Nobuyuki; Kanasaki, Masayoshi; Morimoto, Yu; Okamoto, Satoshi; Ishizuka, Masayuki; Fukuda, Kazuyuki; Takaki, Toshihiko; Tajitsu, Yoshiro

2005-09-01

It is difficult to obtain a drawn chiral polymer/inorganic material composite membrane with shear piezoelectricity by the conventional method because the chiral polymer/inorganic material composite membrane breaks during the drawing process by which shear piezoelectricity is realized. Using a strong magnetic field, we propose to manufacture a drawn composite membrane of poly-l-lactic acid (PLLA), a chiral polymer, and hydroxyapatite (Hap), an inoroganic material (PLLA/Hap composite membrane). The manufacturing method used here is effective for obtaining a drawn PLLA/Hap composite membrane with a large uniform area. Also, the shear piezoelectric constant of the drawn PLLA/Hap composite membrane is about 20 pC/N. This value is large for piezoelectric polymers.

Field-Free Programmable Spin Logics via Chirality-Reversible Spin-Orbit Torque Switching.

PubMed

Wang, Xiao; Wan, Caihua; Kong, Wenjie; Zhang, Xuan; Xing, Yaowen; Fang, Chi; Tao, Bingshan; Yang, Wenlong; Huang, Li; Wu, Hao; Irfan, Muhammad; Han, Xiufeng

2018-06-21

Spin-orbit torque (SOT)-induced magnetization switching exhibits chirality (clockwise or counterclockwise), which offers the prospect of programmable spin-logic devices integrating nonvolatile spintronic memory cells with logic functions. Chirality is usually fixed by an applied or effective magnetic field in reported studies. Herein, utilizing an in-plane magnetic layer that is also switchable by SOT, the chirality of a perpendicular magnetic layer that is exchange-coupled with the in-plane layer can be reversed in a purely electrical way. In a single Hall bar device designed from this multilayer structure, three logic gates including AND, NAND, and NOT are reconfigured, which opens a gateway toward practical programmable spin-logic devices. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Optical resolution of rotenoids

USGS Publications Warehouse

Abidi, S.L.

1987-01-01

Optical resolution of selected rotenoids containing 1-3 asymmetric centers in dihydrobenzopyranofuroben-zopyranone and dihydrobisbenzopyranopyranone series has been achieved on two chiral high-performance liquid chromatographic (hplc) stationary phases. In most cases, the absolute stereochemistry at the cis-B/C ring junction of the rotenoidal antipodes can be related to their elution order. Generally, the 6aα,12aα-enantiomers were more strongly retained by the chiral substrate than their corresponding optical antipodes. The elution-configuration relationship provides potential utility for predicting the absolute configuration of related rotenoidal compounds. Chiral phase hplc on amino-acid-bonded-silica yielded results explicable in terms of Pirkle's bonding schemes for chiral recognition. Resolution data for 12a-hydroxy-, 12a-methoxy-, and 12-hydroxyiminorotenoids further corroborate the mechanistic rationale, and demonstrate that nonpolar π-π interactions appeared to be important for enantiomeric separation on helic poly-triphenylmethylacryl-ate-silica (CPOT). In the latter system, steric effects and conformational factors in association with the modification of E-ring structures might play significant roles in the chiral separation process in view of the reversal to the elution order observed for all methoxylated rotenoids and elliptone derivatives including the parent deguelin. The unique separability (α = 1.44) of 12a-hydroxyelliptone on CPOT was suggestive of structural effects of the 5-side chain on the resolution of the rotenoids having a five-membered-E-ring. The results obtained with two different types of chiral phases are complementary and useful for optical resolution of a wide variety of natural and synthetic rotenoidal compounds.

Pion momentum distributions in the nucleon in chiral effective theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burkardt, Matthias R.; Hendricks, K. S.; Ji, Cheung Ryong

2013-03-01

We compute the light-cone momentum distributions of pions in the nucleon in chiral effective theory using both pseudovector and pseudoscalar pion--nucleon couplings. For the pseudovector coupling we identifymore » $$\\delta$$-function contributions associated with end-point singularities arising from the pion-nucleon rainbow diagrams, as well as from pion tadpole diagrams which are not present in the pseudoscalar model. Gauge invariance is demonstrated, to all orders in the pion mass, with the inclusion of Weinberg-Tomozawa couplings involving operator insertions at the $$\\pi NN$$ vertex. The results pave the way for phenomenological applications of pion cloud models that are manifestly consistent with the chiral symmetry properties of QCD.« less

Strain-induced chiral magnetic effect in Weyl semimetals

DOE PAGES

Cortijo, Alberto; Kharzeev, Dmitri; Landsteiner, Karl; ...

2016-12-19

Here, we argue that strain applied to a time-reversal and inversion breaking Weyl semimetal in a magnetic field can induce an electric current via the chiral magnetic effect. A tight-binding model is used to show that strain generically changes the locations in the Brillouin zone but also the energies of the band touching points (tips of the Weyl cones). Since axial charge in a Weyl semimetal can relax via intervalley scattering processes, the induced current will decay with a time scale given by the lifetime of a chiral quasiparticle. Lastly, we estimate the strength and lifetime of the current formore » typical material parameters and find that it should be experimentally observable.« less

Chiral pesticides: identification, description, and environmental implications.

PubMed

Ulrich, Elin M; Morrison, Candice N; Goldsmith, Michael R; Foreman, William T

2012-01-01

Of the 1,693 pesticides considered in this review, 1,594 are organic chemicals, 47 are inorganic chemicals, 53 are of biological origin (largely non chemical; insect,fungus, bacteria, virus, etc.), and 2 have an undetermined structure. Considering that the EPA's Office of Pesticide Programs found 1,252 pesticide active ingredients(EPA Pesticides Customer Service 2011), we consider this dataset to be comprehensive; however, no direct comparison of the compound lists was undertaken. Of all pesticides reviewed, 482 (28%) are chiral; 30% are chiral when considering only the organic chemical pesticides. A graph of this distribution is shown in Fig. 7a. Each pesticide is classified with up to three pesticidal utilities (e.g., fungicide, plant growth regulator, rodenticide, etc.), taken first from the Pesticide Manual as a primary source, and the Compendium of Common Pesticide Names website as a secondary source. Of the chiral pesticides, 195 (34%) are insecticides (including attractants, pheromones, and repellents), 150 (27%) are herbicides (including plant growth regulators and herbicide safeners), 104 (18%) are fungicides, and 55 (10%)are acaricides. The distribution of chiral pesticides by utility is shown in Fig. 7b,including categories of pesticides that make up 3%t or less of the usage categories.Figure 7c shows a similar distribution of non chiral pesticide usage categories. Of the chiral pesticides, 270 (56%) have one chiral feature, 105 (22%) have two chiral features, 30 (6.2%) have three chiral features, and 29 (6.0%) have ten or more chiral features.Chiral chemicals pose many difficulties in stereospecific synthesis, characterization, and analysis. When these compounds are purposely put into the environment,even more interesting complications arise in tracking, monitoring, and predicting their fate and risks. More than 475 pesticides are chiral, as are other chiral contaminants such as pharmaceuticals, polychlorinated biphenyls, brominated flame retardants, synthetic musks, and their degradates (Kallenborn and Hiihnerfuss 2001;Heeb et al. 2007; Hihnerfuss and Shah 2009). The stereoisomers of pesticides can have widely different efficacy, toxicity to nontarget organisms, and metabolic rates in biota. For these reasons, it is important to first be aware of likely fate and effect differences, to incorporate molecular asymmetry insights into research projects, and to study the individual stereoisomers of the applied pesticide material.With the advent of enantioselective chromatography techniques, the chirality of pesticides has been increasingly studied. While the ChirBase (Advanced ChemistryDevelopment 1997-2010) database does not include all published chiral analytical separations, it does contain more than 3,500 records for 146 of the 482 chiral pesticides (30%). The majority of the records are found in the liquid chromatography database (2,677 or 76%), followed by the gas chromatography database (652 or 18%),and the capillary electrophoresis database (203 or 6%). The finding that only 30% of the chiral pesticides covered in this review have entries in ChirBase highlights the need for expanded efforts to develop additional enantioselective chromatographic methods. Other techniques (e.g., nuclear magnetic resonance and other spectroscopy)are available for investigation of chiral compounds, but often are not utilized because of cost, complexity, or simply not recognizing that a pesticide is chiral.In this review, we have listed and have briefly described the general nature of chiral fungicides, herbicides, insecticides, and other miscellaneous classes. A data-set generated for this review contains 1,693 pesticides, the number of enantioselective separation records in ChirBase, pesticide usage class, SMILES structure string and counts of stereogenic centers. This dataset is publically available for download at the following website: http://www.epa.gov/heasd/products/products.html. With the information herein coupled to the publically accessible dataset, we can begin to develop the tools to handle molecular asymmetry as it applies to agrochemicals.Additional structure-based resources would allow further analysis of key parameters (e.g., exposure, toxicity, environmental fate, degradation, and risks) for individual stereoisomers of chiral compounds.

From quarks to nucleons in dark matter direct detection

NASA Astrophysics Data System (ADS)

Bishara, Fady; Brod, Joachim; Grinstein, Benjamin; Zupan, Jure

2017-11-01

We provide expressions for the nonperturbative matching of the effective field theory describing dark matter interactions with quarks and gluons to the effective theory of nonrelativistic dark matter interacting with nonrelativistic nucleons. We give expressions of leading and subleading order in chiral counting. In general, a single partonic operator matches onto several nonrelativistic operators already at leading order in chiral counting. Keeping only one operator at the time in the nonrelativistic effective theory thus does not properly describe the scattering in direct detection. The matching of the axial-axial partonic level operator, as well as the matching of the operators coupling DM to the QCD anomaly term, include naively momentum suppressed terms. However, these are still of leading chiral order due to pion poles and can be numerically important.

THE ENANTIOMERS OF CHIRAL POLLUTANTS POSE DIFFERENT RISKS

EPA Science Inventory

In order to make more accurate risk assessments for chiral pesticides and other pollutants, it is necessary to understand the relative persistence and effects of their enantiomers. A major effort is underway in the USEPA to measure exposure in the home environment to various pes...

Grasping the Concepts of Stereochemistry.

ERIC Educational Resources Information Center

Barta, Nancy S.; Stille, John R.

1994-01-01

Presents an effective means of determining the R or S configuration of chiral molecules using the Cahn Ingold Prelog (CIP) sequence rules to establish substituent priority and use of the ultimate model of chirality, the hands, to aid in the direct correlation and assignment of relative configuration. (ZWH)

OBSERVATIONS OF ENANTIOSELECTIVITY IN THE FATE, PERSISTENCE AND EFFECTS OF MODERN PESTICIDES

EPA Science Inventory

Chiral pollutants exist as 2 (or more) species, -- enantiomers -- that are non-superimposable mirror images of each other. Enantiomers have identical physical and chemical properties except when they interact with enzymes or other chiral molecules; then they usually react select...

Effective chiral restoration in the ρ' meson in lattice QCD

NASA Astrophysics Data System (ADS)

Glozman, L. Ya.; Lang, C. B.; Limmer, Markus

2010-11-01

In simulations with dynamical quarks it has been established that the ground state ρ in the infrared is a strong mixture of the two chiral representations (0,1)+(1,0) and (1/2,1/2)b. Its angular momentum content is approximately the S13 partial wave. Effective chiral restoration in an excited ρ-meson would require that in the infrared this meson couples predominantly to one of the two representations. The variational method allows one to study the mixing of interpolators with different chiral transformation properties in the nonperturbatively determined excited state at different resolution scales. We present results for the first excited state of the ρ-meson using simulations with nf=2 dynamical quarks. We point out, that in the infrared a leading contribution to ρ'=ρ(1450) comes from (1/2,1/2)b, in contrast to the ρ. The ρ' wave function contains a significant contribution of the D13 wave which is not consistent with the quark model prediction.

Computations of the chirality-sensitive effect induced by an antisymmetric indirect spin–spin coupling

NASA Astrophysics Data System (ADS)

Garbacz, Piotr

2018-05-01

Results of quantum mechanical computations of the antisymmetric part of the indirect spin-spin coupling tensor, ?, performed using the coupled-cluster method, the second-order polarisation propagator approximation, and the density functional theory for 25 molecules and nearly 100 spin-spin couplings are reported. These results are used for an estimation of the magnitude of the recently proposed liquid-state nuclear magnetic resonance chirality-sensitive effect, which allows to determine the molecular chirality directly, i.e. without the need for the application of any chiral agent. The following were found: (i) the antisymmetry J⋆ is usually larger for the coupling between spins separated by two chemical bonds in comparison with the coupling through one bond, (ii) promising samples are those which contain fluorine, and (iii) the antisymmetry of the spin-spin coupling tensor is of the order of a few hertz for commercially available chemical compounds. Therefore, the relevant property of the experiment, the pseudoscalar Jc, for them is of the order of 1 nHz m/V.

High-performance liquid chromatographic enantioseparation of unusual isoxazoline-fused 2-aminocyclopentanecarboxylic acids on macrocyclic glycopeptide-based chiral stationary phases.

PubMed

Sipos, László; Ilisz, István; Nonn, Melinda; Fülöp, Ferenc; Pataj, Zoltán; Armstrong, Daniel W; Péter, Antal

2012-04-06

The enantiomers of four unusual isoxazoline-fused 2-aminocyclopentanecarboxylic acids were directly separated on chiral stationary phases containing macrocyclic glycopeptide antibiotics teicoplanin (Astec Chirobiotic T and T2), teicoplanin aglycone (Chirobiotic TAG), vancomycin (Chirobiotic V) and vancomycin aglycone (Chirobiotic VAG) as chiral selectors. The effects of the mobile phase composition, the structure of the analytes and temperature on the separations were investigated. Experiments were performed at constant mobile phase compositions in the temperature range 5-45 °C to study the effects of temperature, and thermodynamic parameters were calculated from plots of lnk or lnα versus 1/T. Some mechanistic aspects of the chiral recognition process are discussed with respect to the structures of the analytes. It was found that the enantiomeric separations were in most cases enthalpy-driven. The sequence of elution of the enantiomers was determined in all cases. Copyright © 2011 Elsevier B.V. All rights reserved.

Auxiliary field diffusion Monte Carlo calculations of light and medium-mass nuclei with local chiral interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lonardoni, D.; Gandolfi, S.; Lynn, J. E.

Quantum Monte Carlo methods have recently been employed to study properties of nuclei and infinite matter using local chiral effective-field-theory interactions. In this paper, we present a detailed description of the auxiliary field diffusion Monte Carlo algorithm for nuclei in combination with local chiral two- and three-nucleon interactions up to next-to-next-to-leading order. We show results for the binding energy, charge radius, charge form factor, and Coulomb sum rule in nuclei withmore » $$3{\\le}A{\\le}16$$. Particular attention is devoted to the effect of different operator structures in the three-body force for different cutoffs. Finally, the outcomes suggest that local chiral interactions fit to few-body observables give a very good description of the ground-state properties of nuclei up to $$^{16}\\mathrm{O}$$, with the exception of one fit for the softer cutoff which predicts overbinding in larger nuclei.« less

Auxiliary field diffusion Monte Carlo calculations of light and medium-mass nuclei with local chiral interactions

DOE PAGES

Lonardoni, D.; Gandolfi, S.; Lynn, J. E.; ...

2018-04-24

Quantum Monte Carlo methods have recently been employed to study properties of nuclei and infinite matter using local chiral effective-field-theory interactions. In this paper, we present a detailed description of the auxiliary field diffusion Monte Carlo algorithm for nuclei in combination with local chiral two- and three-nucleon interactions up to next-to-next-to-leading order. We show results for the binding energy, charge radius, charge form factor, and Coulomb sum rule in nuclei withmore » $$3{\\le}A{\\le}16$$. Particular attention is devoted to the effect of different operator structures in the three-body force for different cutoffs. Finally, the outcomes suggest that local chiral interactions fit to few-body observables give a very good description of the ground-state properties of nuclei up to $$^{16}\\mathrm{O}$$, with the exception of one fit for the softer cutoff which predicts overbinding in larger nuclei.« less

Effect of basic and acidic additives on the separation of some basic drug enantiomers on polysaccharide-based chiral columns with acetonitrile as mobile phase.

PubMed

Gogaladze, Khatuna; Chankvetadze, Lali; Tsintsadze, Maia; Farkas, Tivadar; Chankvetadze, Bezhan

2015-03-01

The separation of enantiomers of 16 basic drugs was studied using polysaccharide-based chiral selectors and acetonitrile as mobile phase with emphasis on the role of basic and acidic additives on the separation and elution order of enantiomers. Out of the studied chiral selectors, amylose phenylcarbamate-based ones more often showed a chiral recognition ability compared to cellulose phenylcarbamate derivatives. An interesting effect was observed with formic acid as additive on enantiomer resolution and enantiomer elution order for some basic drugs. Thus, for instance, the enantioseparation of several β-blockers (atenolol, sotalol, toliprolol) improved not only by the addition of a more conventional basic additive to the mobile phase, but also by the addition of an acidic additive. Moreover, an opposite elution order of enantiomers was observed depending on the nature of the additive (basic or acidic) in the mobile phase. © 2015 Wiley Periodicals, Inc.

Local light-induced magnetization using nanodots and chiral molecules.

PubMed

Dor, Oren Ben; Morali, Noam; Yochelis, Shira; Baczewski, Lech Tomasz; Paltiel, Yossi

2014-11-12

With the increasing demand for miniaturization, nanostructures are likely to become the primary components of future integrated circuits. Different approaches are being pursued toward achieving efficient electronics, among which are spin electronics devices (spintronics). In principle, the application of spintronics should result in reducing the power consumption of electronic devices. Recently a new, promising, effective approach for spintronics has emerged, using spin selectivity in electron transport through chiral molecules. In this work, using chiral molecules and nanocrystals, we achieve local spin-based magnetization generated optically at ambient temperatures. Through the chiral layer, a spin torque can be transferred without permanent charge transfer from the nanocrystals to a thin ferromagnetic layer, creating local perpendicular magnetization. We used Hall sensor configuration and atomic force microscopy (AFM) to measure the induced local magnetization. At low temperatures, anomalous spin Hall effects were measured using a thin Ni layer. The results may lead to optically controlled spintronics logic devices that will enable low power consumption, high density, and cheap fabrication.

Enhancing and reducing chirality by opposite circularly-polarized light irradiation on crystalline chiral domains consisting of nonchiral photoresponsive W-shaped liquid crystal molecules.

PubMed

Choi, Suk-Won; Takezoe, Hideo

2016-09-28

We found possible chirality enhancement and reduction in chiral domains formed by photoresponsive W-shaped molecules by irradiation with circularly polarized light (CPL). The W-shaped molecules exhibit a unique smectic phase with spontaneously segregated chiral domains, although the molecules are nonchiral. The chirality control was generated in the crystalline phase, which shows chiral segregation as in the upper smectic phase, and the result appeared to be as follows: for a certain chiral domain, right-CPL stimuli enhanced the chirality, while left-CPL stimuli reduced the chirality, and vice versa for another chiral domain. Interestingly, no domain-size change could be observed after CPL irradiation, suggesting some changes in the causes of chirality. In this way, the present system can recognize the handedness of the applied chiral stimuli. In other words, the present material can be used as a sensitive chiral-stimuli-recognizing material and should find invaluable applications, including in chiroptical switches, sensors, and memories as well as in chiral recognition.

Probing chiral superconductivity in Sr 2RuO 4 underneath the surface by point contact measurements

DOE PAGES

Wang, He; Luo, Jiawei; Lou, Weijian; ...

2017-05-08

Sr2RuO4 (SRO) is the prime candidate for a chiral p-wave superconductor with critical temperaturemore » $${T}_{{\\rm{c}}}(\\mathrm{SRO})\\sim 1.5$$ K. Chiral domains with opposite chiralities $${p}_{x}\\pm {{\\rm{i}}{p}}_{y}$$ have been proposed, but are yet to be confirmed. We measure the field dependence of the point contact (PC) resistance between a tungsten tip and an SRO–Ru eutectic crystal, where micrometer-sized Ru inclusions are embedded in SRO with an atomically sharp interface. Ruthenium is an s-wave superconductor with $${T}_{{\\rm{c}}}(\\mathrm{Ru})\\sim 0.5$$ K; flux pinned near the Ru inclusions can suppress its superconductivity, as reflected in the PC resistance and spectra. This flux pinning effect originates from SRO underneath the surface and is very strong once flux is introduced. To fully remove flux pinning, one needs to thermally cycle the sample above T c(SRO) or apply alternating fields with decreasing amplitude. With alternating fields, the observed hysteresis in magnetoresistance can be explained by domain dynamics, providing support for the existence of chiral domains. The origin of the strong pinning could be the chiral domains themselves.« less

Probing chiral superconductivity in Sr2RuO4 underneath the surface by point contact measurements

NASA Astrophysics Data System (ADS)

Wang, He; Luo, Jiawei; Lou, Weijian; Ortmann, J. E.; Mao, Z. Q.; Liu, Y.; Wei, Jian

2017-05-01

Sr2RuO4 (SRO) is the prime candidate for a chiral p-wave superconductor with critical temperature {T}{{c}}({SRO})˜ 1.5 K. Chiral domains with opposite chiralities {p}x+/- {{{i}}{p}}y have been proposed, but are yet to be confirmed. We measure the field dependence of the point contact (PC) resistance between a tungsten tip and an SRO-Ru eutectic crystal, where micrometer-sized Ru inclusions are embedded in SRO with an atomically sharp interface. Ruthenium is an s-wave superconductor with {T}{{c}}({Ru})˜ 0.5 K; flux pinned near the Ru inclusions can suppress its superconductivity, as reflected in the PC resistance and spectra. This flux pinning effect originates from SRO underneath the surface and is very strong once flux is introduced. To fully remove flux pinning, one needs to thermally cycle the sample above T c(SRO) or apply alternating fields with decreasing amplitude. With alternating fields, the observed hysteresis in magnetoresistance can be explained by domain dynamics, providing support for the existence of chiral domains. The origin of the strong pinning could be the chiral domains themselves.

Capillary electrophoresis of covalently functionalized single-chirality carbon nanotubes.

PubMed

He, Pingli; Meany, Brendan; Wang, Chunyan; Piao, Yanmei; Kwon, Hyejin; Deng, Shunliu; Wang, YuHuang

2017-07-01

We demonstrate the separation of chirality-enriched single-walled carbon nanotubes (SWCNTs) by degree of surface functionalization using high-performance CE. Controlled amounts of negatively charged and positively charged functional groups were attached to the sidewall of chirality-enriched SWCNTs through covalent functionalization using 4-carboxybenzenediazonium tetrafluoroborate or 4-diazo-N,N-diethylaniline tetrafluoroborate, respectively. Surfactant- and pH-dependent studies confirmed that under conditions that minimized ionic screening effects, separation of these functionalized SWCNTs was strongly dependent on the surface charge density introduced through covalent surface chemistry. For both heterogeneous mixtures and single-chirality-enriched samples, covalently functionalized SWCNTs showed substantially increased peak width in electropherogram spectra compared to nonfunctionalized SWCNTs, which can be attributed to a distribution of surface charges along the functionalized nanotubes. Successful separation of functionalized single-chirality SWCNTs by functional density was confirmed with UV-Vis-NIR absorption and Raman scattering spectroscopies of fraction collected samples. These results suggest a high degree of structural heterogeneity in covalently functionalized SWCNTs, even for chirality-enriched samples, and show the feasibility of applying CE for high-performance separation of nanomaterials based on differences in surface functional density. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Cellular and Nuclear Alignment Analysis for Determining Epithelial Cell Chirality

PubMed Central

Raymond, Michael J.; Ray, Poulomi; Kaur, Gurleen; Singh, Ajay V.; Wan, Leo Q.

2015-01-01

Left-right (LR) asymmetry is a biologically conserved property in living organisms that can be observed in the asymmetrical arrangement of organs and tissues and in tissue morphogenesis, such as the directional looping of the gastrointestinal tract and heart. The expression of LR asymmetry in embryonic tissues can be appreciated in biased cell alignment. Previously an in vitro chirality assay was reported by patterning multiple cells on microscale defined geometries and quantified the cell phenotype–dependent LR asymmetry, or cell chirality. However, morphology and chirality of individual cells on micropatterned surfaces has not been well characterized. Here, a Python-based algorithm was developed to identify and quantify immunofluorescence stained individual epithelial cells on multicellular patterns. This approach not only produces results similar to the image intensity gradient-based method reported previously, but also can capture properties of single cells such as area and aspect ratio. We also found that cell nuclei exhibited biased alignment. Around 35% cells were misaligned and were typically smaller and less elongated. This new imaging analysis approach is an effective tool for measuring single cell chirality inside multicellular structures and can potentially help unveil biophysical mechanisms underlying cellular chiral bias both in vitro and in vivo. PMID:26294010

Enantioseparation of Mandelic Acid Enantiomers With Magnetic Nano-Sorbent Modified by a Chiral Selector.

PubMed

Tarhan, Tuba; Tural, Bilsen; Tural, Servet; Topal, Giray

2015-11-01

In this study, R(+)-α-methylbenzylamine-modified magnetic chiral sorbent was synthesized and assessed as a new enantioselective solid phase sorbent for separation of mandelic acid enantiomers from aqueous solutions. The chemical structures and magnetic properties of the new sorbent were characterized by vibrating sample magnetometry, transmission electron microscopy, Fourier transform infrared spectroscopy, and dynamic light scattering. The effects of different variables such as the initial concentration of racemic mandelic acid, dosage of sorbent, and contact time upon sorption characteristics of mandelic acid enantiomers on magnetic chiral sorbent were investigated. The sorption of mandelic acid enantiomers followed a pseudo-second-order reaction and equilibrium experiments were well fitted to a Langmuir isotherm model. The maximum adsorption capacity of racemic mandelic acid on to the magnetic chiral sorbent was found to be 405 mg g(-1). The magnetic chiral sorbent has a greater affinity for (S)-(+)-mandelic acid compared to (R)-(-)-mandelic acid. The optimum resolution was achieved with 10 mL 30 mM of racemic mandelic acid and 110 mg of magnetic chiral sorbent. The best percent enantiomeric excess values (up to 64%) were obtained by use of a chiralpak AD-H column. © 2015 Wiley Periodicals, Inc.

Long-range Coulomb interaction effects on the topological phase transitions between semimetals and insulators

NASA Astrophysics Data System (ADS)

Han, SangEun; Moon, Eun-Gook

2018-06-01

Topological states may be protected by a lattice symmetry in a class of topological semimetals. In three spatial dimensions, the Berry flux around gapless excitations in momentum space concretely defines a chirality, so a protecting symmetry may be referred to as a chiral symmetry. Prime examples include a Dirac semimetal (DSM) in a distorted spinel, BiZnSiO4, protected by a mirror symmetry, and a DSM in Na3Bi , protected by a rotational symmetry. In these states, topology and chiral symmetry are intrinsically tied. In this Rapid Communication, the characteristic interplay between a chiral symmetry order parameter and an instantaneous long-range Coulomb interaction is investigated with the standard renormalization group method. We show that a topological transition associated with chiral symmetry is stable under the presence of a Coulomb interaction and the electron velocity always becomes faster than the one of a chiral symmetry order parameter. Thus, the transition must not be relativistic, which implies that supersymmetry is intrinsically forbidden by the long-range Coulomb interaction. Asymptotically exact universal ratios of physical quantities such as the energy gap ratio are obtained, and connections with experiments and recent theoretical proposals are also discussed.

An ion-pair principle for enantioseparations of basic analytes by nonaqueous capillary electrophoresis using the di-n-butyl L-tartrate-boric acid complex as chiral selector.

PubMed

Wang, Li-Juan; Liu, Xiu-Feng; Lu, Qie-Nan; Yang, Geng-Liang; Chen, Xing-Guo

2013-04-05

A chiral recognition mechanism of ion-pair principle has been proposed in this study. It rationalized the enantioseparations of some basic analytes using the complex of di-n-butyl l-tartrate and boric acid as the chiral selector in methanolic background electrolytes (BGEs) by nonaqueous capillary electrophoresis (NACE). An approach of mass spectrometer (MS) directly confirmed that triethylamine promoted the formation of negatively charged di-n-butyl l-tartrate-boric acid complex chiral counter ion with a complex ratio of 2:1. And the negatively charged counter ion was the real chiral selector in the ion-pair principle enantioseparations. It was assumed that triethylamine should play its role by adjusting the apparent acidity (pH*) of the running buffer to a higher value. Consequently, the effects of various basic electrolytes including inorganic and organic ones on the enantioseparations in NACE were investigated. The results showed that most of the basic electrolytes tested were favorable for the enantioseparations of basic analytes using di-n-butyl l-tartrate-boric acid complex as the chiral ion-pair selector. Copyright © 2013 Elsevier B.V. All rights reserved.

Brilliant Sm, Eu, Tb and Dy chiral lanthanide complexes withstrong circularly polarized luminescence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Petoud, Stephane; Muller, Gilles; Moore, Evan G.

The synthesis, characterization and luminescent behavior of trivalent Sm, Eu, Dy and Tb complexes of two enantiomeric, octadentate, chiral, 2-hydroxyisophthalamide ligands are reported. These complexes are highly luminescent in solution. Functionalization of the achiral parent ligand with a chiral 1-phenylethylamine substituent on the open face of the complex in close proximity to the metal center yields complexes with strong circularly polarized luminescence (CPL) activity. This appears to be the first example of a system utilizing the same ligand architecture to sensitize four different lanthanide cations and display CPL activity. The luminescence dissymmetry factor, g{sub lum}, recorded for the Eu(III) complexmore » is one of the highest values reported, and this is the first time the CPL effect has been demonstrated for a Sm(III) complex with a chiral ligand. The combination of high luminescence intensity with CPL activity should enable new bioanalytical applications of macromolecules in chiral environments.« less

Chiral light intrinsically couples to extrinsic/pseudo-chiral metasurfaces made of tilted gold nanowires

PubMed Central

Belardini, Alessandro; Centini, Marco; Leahu, Grigore; Hooper, David C.; Li Voti, Roberto; Fazio, Eugenio; Haus, Joseph W.; Sarangan, Andrew; Valev, Ventsislav K.; Sibilia, Concita

2016-01-01

Extrinsic or pseudo-chiral (meta)surfaces have an achiral structure, yet they can give rise to circular dichroism when the experiment itself becomes chiral. Although these surfaces are known to yield differences in reflected and transmitted circularly polarized light, the exact mechanism of the interaction has never been directly demonstrated. Here we present a comprehensive linear and nonlinear optical investigation of a metasurface composed of tilted gold nanowires. In the linear regime, we directly demonstrate the selective absorption of circularly polarised light depending on the orientation of the metasurface. In the nonlinear regime, we demonstrate for the first time how second harmonic generation circular dichroism in such extrinsic/pseudo-chiral materials can be understood in terms of effective nonlinear susceptibility tensor elements that switch sign depending on the orientation of the metasurface. By providing fundamental understanding of the chiroptical interactions in achiral metasurfaces, our work opens up new perspectives for the optimisation of their properties. PMID:27553888

Self-similar inverse cascade of magnetic helicity driven by the chiral anomaly

DOE PAGES

Hirono, Yuji; Kharzeev, Dmitri E.; Yin, Yi

2015-12-28

For systems with charged chiral fermions, the imbalance of chirality in the presence of magnetic field generates an electric current—this is the chiral magnetic effect (CME). We study the dynamical real-time evolution of electromagnetic fields coupled by the anomaly to the chiral charge density and the CME current by solving the Maxwell-Chern-Simons equations. We find that the CME induces the inverse cascade of magnetic helicity toward the large distances, and that at late times this cascade becomes self-similar, with universal exponents. We also find that in terms of gauge field topology the inverse cascade represents the transition from linked electricmore » and magnetic fields (Hopfions) to the knotted configuration of magnetic field (Chandrasekhar-Kendall states). The magnetic reconnections are accompanied by the pulses of the CME current directed along the magnetic field lines. In conclusion, we devise an experimental signature of these phenomena in heavy ion collisions, and speculate about implications for condensed matter systems.« less

Emergent Chiral Spin State in the Mott Phase of a Bosonic Kane-Mele-Hubbard Model

NASA Astrophysics Data System (ADS)

Plekhanov, Kirill; Vasić, Ivana; Petrescu, Alexandru; Nirwan, Rajbir; Roux, Guillaume; Hofstetter, Walter; Le Hur, Karyn

2018-04-01

Recently, the frustrated X Y model for spins 1 /2 on the honeycomb lattice has attracted a lot of attention in relation with the possibility to realize a chiral spin liquid state. This model is relevant to the physics of some quantum magnets. Using the flexibility of ultracold atom setups, we propose an alternative way to realize this model through the Mott regime of the bosonic Kane-Mele-Hubbard model. The phase diagram of this model is derived using bosonic dynamical mean-field theory. Focusing on the Mott phase, we investigate its magnetic properties as a function of frustration. We do find an emergent chiral spin state in the intermediate frustration regime. Using exact diagonalization we study more closely the physics of the effective frustrated X Y model and the properties of the chiral spin state. This gapped phase displays a chiral order, breaking time-reversal and parity symmetry, but is not topologically ordered (the Chern number is zero).

Transport and collective radiance in a basic quantum chiral optical model

NASA Astrophysics Data System (ADS)

Kornovan, D. F.; Petrov, M. I.; Iorsh, I. V.

2017-09-01

In our work, we theoretically study the dynamics of a single excitation in a one-dimensional array of two-level systems, which are chirally coupled through a single mode waveguide. The chirality is achieved owing to a strong optical spin-locking effect, which in an ideal case gives perfect unidirectional excitation transport. We obtain a simple analytical solution for a single excitation dynamics in the Markovian limit, which directly shows the tolerance of the system with respect to the fluctuations of emitters position. We also show that the Dicke state, which is well known to be superradiant, has twice lower emission rate in the case of unidirectional quantum interaction. Our model is supported and verified with the numerical computations of quantum emitters coupled via surface plasmon modes in a metallic nanowire. The obtained results are based on a very general model and can be applied to any chirally coupled system that gives a new outlook on quantum transport in chiral nanophotonics.

Chiral density wave versus pion condensation at finite density and zero temperature

NASA Astrophysics Data System (ADS)

Andersen, Jens O.; Kneschke, Patrick

2018-04-01

The quark-meson model is often used as a low-energy effective model for QCD to study the chiral transition at finite temperature T , baryon chemical potential μB , and isospin chemical potential μI . We determine the parameters of the model by matching the meson and quark masses, as well as the pion decay constant to their physical values using the on shell (OS) and modified minimal subtraction (MS ¯ ) schemes. In this paper, the existence of different phases at zero temperature is studied. In particular, we investigate the competition between an inhomogeneous chiral condensate and a homogeneous pion condensate. For the inhomogeneity, we use a chiral-density wave ansatz. For a sigma mass of 600 MeV, we find that an inhomogeneous chiral condensate exists only for pion masses below approximately 37 MeV. We also show that due to our parameter fixing, the onset of pion condensation takes place exactly at μIc=1/2 mπ in accordance with exact results.

FDTD chiral brain tissue model for specific absorption rate determination under radiation from mobile phones at 900 and 1800 MHz

NASA Astrophysics Data System (ADS)

Zamorano, M.; Torres-Silva, H.

2006-04-01

A new electrodynamics model formed by chiral bioplasma, which represents the human head inner structure and makes it possible to analyse its behaviour when it is irradiated by a microwave electromagnetic field from cellular phones, is presented. The finite-difference time-domain (FDTD) numeric technique is used, which allows simulation of the electromagnetic fields, deduced with Maxwell's equations, and allows us to simulate the specific absorption rate (SAR). The results show the SAR behaviour as a function of the input power and the chirality factor. In considering the chiral brain tissue in the proposed human head model, the two more important conclusions of our work are the following: (a) the absorption of the electromagnetic fields from cellular phones is stronger, so the SAR coefficient is higher than that using the classical model, when values of the chiral factor are of order of 1; (b) 'inverse skin effect' shows up at 1800 MHz, with respect to a 900 MHz source.

Chiral topological superconductor and half-integer conductance plateau from quantum anomalous Hall plateau transition

DOE PAGES

Wang, Jing; Zhou, Quan; Lian, Biao; ...

2015-08-31

Here, we propose to realize a two-dimensional chiral topological superconducting (TSC) state from the quantum anomalous Hall plateau transition in a magnetic topological insulator thin film through the proximity effect to a conventional s -wave superconductor. This state has a full pairing gap in the bulk and a single chiral Majorana mode at the edge. The optimal condition for realizing such chiral TSC is to have inequivalent superconducting pairing amplitudes on top and bottom surfaces of the doped magnetic topological insulator. We further propose several transport experiments to detect the chiral TSC. One unique signature is that the conductance willmore » be quantized into a half-integer plateau at the coercive field in this hybrid system. In particular, with the point contact formed by a superconducting junction, the conductance oscillates between e 2 /2h and e2 /h with the frequency determined by the voltage across the junction. We close by discussing the feasibility of these experimental proposals.« less

The chiral separation of triazole pesticides enantiomers by amylose-tris (3,5-dimethylphenylcarbamate) chiral stationary phase.

PubMed

Wang, Peng; Liu, Donghui; Jiang, Shuren; Xu, Yangguang; Zhou, Zhiqiang

2008-10-01

The amylose-tris(3,5-dimethylphenylcarbamate) chiral stationary phase was synthesized and used to separate the enantiomers of triazole pesticides by high-performance liquid chromatography. The mobile phase was n-hexane-isopropanol applying a flow rate of 1.0 mL/min. Six triazole pesticides were enantioselectively separated. Myclobutanil, paclobutrazol, tebuconazole, and uniconazole obtained complete separation with the resolution factors of 5.73, 2.99, 1.72, and 2.07, respectively, and imazalil and diniconazole obtained partial separation with the resolution factors of 0.79 and 0.77 under the optimized conditions. The effect of the content of isopropanol as well as column temperature on the separation was investigated. A circular dichroism detector was used to identify the enantiomers and determine the elution orders. The results showed the low temperature was good for the chiral separation except for diniconazole. The thermodynamic parameters calculated based on linear Van't Hoff plots showed the chiral separations were controlled by enthalpy.

HPLC of fluoroquinolone antibacterials using chiral stationary phase based on enantiomeric (3,3'-diphenyl-1,1'-binaphthyl)-20-crown-6.

PubMed

Choi, Hee Jung; Cho, Hwan Sun; Han, Sang Cheol; Hyun, Myung Ho

2009-02-01

A residual silanol group-protecting chiral stationary phase (CSP) based on optically active (3,3'-diphenyl-1,1'-binaphthyl)-20-crown-6 was successfully applied to the resolution of fluoroquinolone compounds including gemifloxacin mesylate. The chiral recognition ability of the residual silanol group-protecting CSP was generally greater than that of the residual silanol group-containing CSP. From these results, it was concluded that the simple protection of the residual silanol groups of the latter CSP with lipophilic n-octyl groups can improve its chiral recognition ability for the resolution of racemic fluoroquinolone compounds. The chromatographic resolution behaviors were investigated as a function of the content and type of organic and acidic modifiers and the ammonium acetate concentration in aqueous mobile phase and the column temperature. Especially, the addition of ammonium acetate to the mobile phase was found to be a quite effective means of reducing the enantiomer retentions without sacrificing the chiral recognition efficiency of the CSP.

Chiral topological superconductor and half-integer conductance plateau from quantum anomalous Hall plateau transition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Jing; Zhou, Quan; Lian, Biao

Here, we propose to realize a two-dimensional chiral topological superconducting (TSC) state from the quantum anomalous Hall plateau transition in a magnetic topological insulator thin film through the proximity effect to a conventional s -wave superconductor. This state has a full pairing gap in the bulk and a single chiral Majorana mode at the edge. The optimal condition for realizing such chiral TSC is to have inequivalent superconducting pairing amplitudes on top and bottom surfaces of the doped magnetic topological insulator. We further propose several transport experiments to detect the chiral TSC. One unique signature is that the conductance willmore » be quantized into a half-integer plateau at the coercive field in this hybrid system. In particular, with the point contact formed by a superconducting junction, the conductance oscillates between e 2 /2h and e2 /h with the frequency determined by the voltage across the junction. We close by discussing the feasibility of these experimental proposals.« less

Quantum Monte Carlo calculations of neutron matter with chiral three-body forces

DOE PAGES

Tews, I.; Gandolfi, Stefano; Gezerlis, A.; ...

2016-02-02

Chiral effective field theory (EFT) enables a systematic description of low-energy hadronic interactions with controlled theoretical uncertainties. For strongly interacting systems, quantum Monte Carlo (QMC) methods provide some of the most accurate solutions, but they require as input local potentials. We have recently constructed local chiral nucleon-nucleon (NN) interactions up to next-to-next-to-leading order (N 2LO). Chiral EFT naturally predicts consistent many-body forces. In this paper, we consider the leading chiral three-nucleon (3N) interactions in local form. These are included in auxiliary field diffusion Monte Carlo (AFDMC) simulations. We present results for the equation of state of neutron matter and formore » the energies and radii of neutron drops. Specifically, we study the regulator dependence at the Hartree-Fock level and in AFDMC and find that present local regulators lead to less repulsion from 3N forces compared to the usual nonlocal regulators.« less

Fractional Quantum Hall Effect in n = 0 Landau Band of Graphene with Chern Number Matrix

NASA Astrophysics Data System (ADS)

Kudo, Koji; Hatsugai, Yasuhiro

2018-06-01

Fully taking into account the honeycomb lattice structure, fractional quantum Hall states of graphene are considered by a pseudopotential projected into the n = 0 Landau band. By using chirality as an internal degree of freedom, the Chern number matrices are defined and evaluated numerically. Quantum phase transition induced by changing a range of the interaction is demonstrated that is associated with chirality ferromagnetism. The chirality-unpolarized ground state is consistent with the Halperin 331 state of the bilayer quantum Hall system.

Chiral pesticides: Identification, description, and environmental implications

USGS Publications Warehouse

Ulrich, Elin M.; Morrison, Candice N.; Goldsmith, Michael R.; Foreman, William T.

2012-01-01

Anthropogenic chemicals, including pesticides, are a major source of contamination and pollution in the environment. Pesticides have many positive uses: increased food production, decreased damage to crops and structures, reduced disease vector populations, and more. Nevertheless, pesticide exposure can pose risks to humans and the environment, so various mitigation strategies are exercised to make them safer, minimize their use, and reduce their unintended environment effects. One strategy that may help achieve these goals relies on the unique properties of chirality or molecular asymmetry. Some common terms related to chirality are defined in Table 1.

Enantioseparation of Six Antihistamines with Immobilized Cellulose Chiral Stationary Phase by HPLC

PubMed Central

Zhou, Jie; Luo, Pei; Chen, Shanshan; Meng, Lingchang; Sun, Chong; Du, Qiuzheng; Sun, Fang

2016-01-01

A stereoselective high performance liquid chromatography method has been developed for the chiral separation of the enantiomers of six antihistamines, doxylamine, carbinoxamine, dioxopromethazine, oxomemazine, cetirizine and hydroxyzine. The effects of mobile phase additive, column temperature and flow rate on the retention time and resolution were studied. Enantiomeric separation of cetirizine, doxylamine and hydroxyzine were achieved on cellulose tris-(3,5-dichlorophenylcarbamate) immobilized on silica gel chiral stationary phase known as Chiralpak IC (RS = 3.74, RS = 1.85 and RS = 1.74, respectively). PMID:26657408

Infrared length scale and extrapolations for the no-core shell model

DOE PAGES

Wendt, K. A.; Forssén, C.; Papenbrock, T.; ...

2015-06-03

In this paper, we precisely determine the infrared (IR) length scale of the no-core shell model (NCSM). In the NCSM, the A-body Hilbert space is truncated by the total energy, and the IR length can be determined by equating the intrinsic kinetic energy of A nucleons in the NCSM space to that of A nucleons in a 3(A-1)-dimensional hyper-radial well with a Dirichlet boundary condition for the hyper radius. We demonstrate that this procedure indeed yields a very precise IR length by performing large-scale NCSM calculations for 6Li. We apply our result and perform accurate IR extrapolations for bound statesmore » of 4He, 6He, 6Li, and 7Li. Finally, we also attempt to extrapolate NCSM results for 10B and 16O with bare interactions from chiral effective field theory over tens of MeV.« less

Intrinsic and Extrinsic Origins of the Polar Kerr Effect in a Chiral p-WAVE Superconductor

NASA Astrophysics Data System (ADS)

Goryo, Jun

Recently, the measurement of the polar Kerr effect (PKE) in the quasi two-dimensional superconductor Sr2RuO4, which is motivated to observe the chirality of px + ipy-wave pairing, has been reported. We clarify that the PKE has intrinsic and extrinsic (disorder-induced) origins. The extrinsic contribution would be dominant in the PKE experiment.

Statistical uncertainties of a chiral interaction at next-to-next-to leading order

DOE PAGES

Ekström, A.; Carlsson, B. D.; Wendt, K. A.; ...

2015-02-05

In this paper, we have quantified the statistical uncertainties of the low-energy coupling-constants (LECs) of an optimized nucleon–nucleon interaction from chiral effective field theory at next-to-next-to-leading order. Finally, in addition, we have propagated the impact of the uncertainties of the LECs to two-nucleon scattering phase shifts, effective range parameters, and deuteron observables.

A relativistic neutron fireball from a supernova explosion as a possible source of chiral influence.

PubMed

Gusev, G A; Saito, T; Tsarev, V A; Uryson, A V

2007-06-01

We elaborate on a previously proposed idea that polarized electrons produced from neutrons, released in a supernova (SN) explosion, can cause chiral dissymmetry of molecules in interstellar gas-dust clouds. A specific physical mechanism of a relativistic neutron fireball with Lorentz factor of the order of 100 is assumed for propelling a great number of free neutrons outside the dense SN shell. A relativistic chiral electron-proton plasma, produced from neutron decays, is slowed down owing to collective effects in the interstellar plasma. As collective effects do not involve the particle spin, the electrons can carry their helicities to the cloud. The estimates show high chiral efficiency of such electrons. In addition to this mechanism, production of circularly polarized ultraviolet photons through polarized-electron bremsstrahlung at an early stage of the fireball evolution is considered. It is shown that these photons can escape from the fireball plasma. However, for an average density of neutrals in the interstellar medium of the order of 0.2 cm(-3) and at distances of the order of 10 pc from the SN, these photons will be absorbed with a factor of about 10(-7) due to the photoeffect. In this case, their chiral efficiency will be about five orders of magnitude less than that for polarized electrons.

Chiral Gold Nanoclusters: Atomic Level Origins of Chirality.

PubMed

Zeng, Chenjie; Jin, Rongchao

2017-08-04

Chiral nanomaterials have received wide interest in many areas, but the exact origin of chirality at the atomic level remains elusive in many cases. With recent significant progress in atomically precise gold nanoclusters (e.g., thiolate-protected Au n (SR) m ), several origins of chirality have been unveiled based upon atomic structures determined by using single-crystal X-ray crystallography. The reported chiral Au n (SR) m structures explicitly reveal a predominant origin of chirality that arises from the Au-S chiral patterns at the metal-ligand interface, as opposed to the chiral arrangement of metal atoms in the inner core (i.e. kernel). In addition, chirality can also be introduced by a chiral ligand, manifested in the circular dichroism response from metal-based electronic transitions other than the ligand's own transition(s). Lastly, the chiral arrangement of carbon tails of the ligands has also been discovered in a very recent work on chiral Au 133 (SR) 52 and Au 246 (SR) 80 nanoclusters. Overall, the origins of chirality discovered in Au n (SR) m nanoclusters may provide models for the understanding of chirality origins in other types of nanomaterials and also constitute the basis for the development of various applications of chiral nanoparticles. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Light-Nuclei Spectra from Chiral Dynamics

NASA Astrophysics Data System (ADS)

Piarulli, M.; Baroni, A.; Girlanda, L.; Kievsky, A.; Lovato, A.; Lusk, Ewing; Marcucci, L. E.; Pieper, Steven C.; Schiavilla, R.; Viviani, M.; Wiringa, R. B.

2018-02-01

In recent years local chiral interactions have been derived and implemented in quantum Monte Carlo methods in order to test to what extent the chiral effective field theory framework impacts our knowledge of few- and many-body systems. In this Letter, we present Green's function Monte Carlo calculations of light nuclei based on the family of local two-body interactions presented by our group in a previous paper in conjunction with chiral three-body interactions fitted to bound- and scattering-state observables in the three-nucleon sector. These interactions include Δ intermediate states in their two-pion-exchange components. We obtain predictions for the energy levels and level ordering of nuclei in the mass range A =4 - 12 , accurate to ≤2 % of the binding energy, in very satisfactory agreement with experimental data.

Chirality and gravitational parity violation.

PubMed

Bargueño, Pedro

2015-06-01

In this review, parity-violating gravitational potentials are presented as possible sources of both true and false chirality. In particular, whereas phenomenological long-range spin-dependent gravitational potentials contain both truly and falsely chiral terms, it is shown that there are models that extend general relativity including also coupling of fermionic degrees of freedom to gravity in the presence of torsion, which give place to short-range truly chiral interactions similar to that usually considered in molecular physics. Physical mechanisms which give place to gravitational parity violation together with the expected size of the effects and their experimental constraints are discussed. Finally, the possible role of parity-violating gravity in the origin of homochirality and a road map for future research works in quantum chemistry is presented. © 2015 Wiley Periodicals, Inc.

TaRh2B2 and NbRh2B2: Superconductors with a chiral noncentrosymmetric crystal structure.

PubMed

Carnicom, Elizabeth M; Xie, Weiwei; Klimczuk, Tomasz; Lin, Jingjing; Górnicka, Karolina; Sobczak, Zuzanna; Ong, Nai Phuan; Cava, Robert J

2018-05-01

It is a fundamental truth in solid compounds that the physical properties follow the symmetry of the crystal structure. Nowhere is the effect of symmetry more pronounced than in the electronic and magnetic properties of materials-even the projection of the bulk crystal symmetry onto different crystal faces is known to have a substantial impact on the surface electronic states. The effect of bulk crystal symmetry on the properties of superconductors is widely appreciated, although its study presents substantial challenges. The effect of a lack of a center of symmetry in a crystal structure, for example, has long been understood to necessitate that the wave function of the collective electron state that gives rise to superconductivity has to be more complex than usual. However, few nonhypothetical materials, if any, have actually been proven to display exotic superconducting properties as a result. We introduce two new superconductors that in addition to having noncentrosymmetric crystal structures also have chiral crystal structures. Because the wave function of electrons in solids is particularly sensitive to the host material's symmetry, crystal structure chirality is expected to have a substantial effect on their superconducting wave functions. Our two experimentally obtained chiral noncentrosymmetric superconducting materials have transition temperatures to superconductivity that are easily experimentally accessible, and our basic property characterization suggests that their superconducting properties may be unusual. We propose that their study may allow for a more in-depth understanding of how chirality influences the properties of superconductors and devices that incorporate them.

Chiral signs of TPPS co-assemblies with chiral gelators: role of molecular and supramolecular chirality.

PubMed

Wang, Qiuling; Zhang, Li; Yang, Dong; Li, Tiesheng; Liu, Minghua

2016-10-13

A dianionic tetrakis(4-sulfonatophenyl)porphyrin (TPPS) self-assembled into J-aggregates when it co-assembled with a chiral cationic amphiphile via supramolecular gelation. The chiral signs of TPPS J aggregates followed the supramolecular chirality of amphiphilic assemblies rather than the molecular chirality of the amphiphile.

Formation of Enhanced Uniform Chiral Fields in Symmetric Dimer Nanostructures

PubMed Central

Tian, Xiaorui; Fang, Yurui; Sun, Mengtao

2015-01-01

Chiral fields with large optical chirality are very important in chiral molecules analysis, sensing and other measurements. Plasmonic nanostructures have been proposed to realize such super chiral fields for enhancing weak chiral signals. However, most of them cannot provide uniform chiral near-fields close to the structures, which makes these nanostructures not so efficient for applications. Plasmonic helical nanostructures and blocked squares have been proved to provide uniform chiral near-fields, but structure fabrication is a challenge. In this paper, we show that very simple plasmonic dimer structures can provide uniform chiral fields in the gaps with large enhancement of both near electric fields and chiral fields under linearly polarized light illumination with polarization off the dimer axis at dipole resonance. An analytical dipole model is utilized to explain this behavior theoretically. 30 times of volume averaged chiral field enhancement is gotten in the whole gap. Chiral fields with opposite handedness can be obtained simply by changing the polarization to the other side of the dimer axis. It is especially useful in Raman optical activity measurement and chiral sensing of small quantity of chiral molecule. PMID:26621558

Experimental demonstration of topologically protected efficient sound propagation in an acoustic waveguide network

NASA Astrophysics Data System (ADS)

Wei, Qi; Tian, Ye; Zuo, Shu-Yu; Cheng, Ying; Liu, Xiao-Jun

2017-03-01

Acoustic topological states support sound propagation along the boundary in a one-way direction with inherent robustness against defects and disorders, leading to the revolution of the manipulation on acoustic waves. A variety of acoustic topological states relying on circulating fluid, chiral coupling, or temporal modulation have been proposed theoretically. However, experimental demonstration has so far remained a significant challenge, due to the critical limitations such as structural complexity and high losses. Here, we experimentally demonstrate an acoustic anomalous Floquet topological insulator in a waveguide network. The acoustic gapless edge states can be found in the band gap when the waveguides are strongly coupled. The scheme features simple structure and high-energy throughput, leading to the experimental demonstration of efficient and robust topologically protected sound propagation along the boundary. The proposal may offer a unique, promising application for design of acoustic devices in acoustic guiding, switching, isolating, filtering, etc.

Estimation of the chiral magnetic effect considering the magnetic field response of the QGP medium

NASA Astrophysics Data System (ADS)

Feng, Sheng-Qin; Ai, Xin; Pei, Lei; Sun, Fei; Zhong, Yang; Yin, Zhong-Bao

2018-05-01

The magnetic field plays a major role in searching for the chiral magnetic effect in relativistic heavy-ion collisions. If the lifetime of the magnetic field is too short, as predicted by simulations of the field in vacuum, the chiral magnetic effect will be largely suppressed. However, the lifetime of the magnetic field will become longer when the QGP medium response is considered. We give an estimate of the effect, especially considering the magnetic field response of the QGP medium, and compare it with the experimental results for the background-subtracted correlator H at RHIC and LHC energies. The results show that our method explains the experimental results better at the top RHIC energy than at the LHC energy. Supported by National Natural Science Foundation of China (11747115, 11475068), the CCNU-QLPL Innovation Fund (QLPL2016P01) and the Excellent Youth Foundation of Hubei Scientific Committee (2006ABB036)

Chiral Separations

NASA Astrophysics Data System (ADS)

Stalcup, A. M.

2010-07-01

The main goal of this review is to provide a brief overview of chiral separations to researchers who are versed in the area of analytical separations but unfamiliar with chiral separations. To researchers who are not familiar with this area, there is currently a bewildering array of commercially available chiral columns, chiral derivatizing reagents, and chiral selectors for approaches that span the range of analytical separation platforms (e.g., high-performance liquid chromatography, gas chromatography, supercritical-fluid chromatography, and capillary electrophoresis). This review begins with a brief discussion of chirality before examining the general strategies and commonalities among all of the chiral separation techniques. Rather than exhaustively listing all the chiral selectors and applications, this review highlights significant issues and differences between chiral and achiral separations, providing salient examples from specific classes of chiral selectors where appropriate.

Enhanced Stereoselectivity of a Cu(II) Complex Chiral Auxiliary in the Synthesis of Fmoc-L-γ-carboxyglutamic Acid | Center for Cancer Research

Cancer.gov

Bridging bioinorganic chemistry with asymmetric synthesis: a naturally occurring metalloprotein is used for the structure-based evolution of chiral auxiliaries that prove to be effective in the synthesis of Fmoc-L-γ-carboxyglutamic acid.

Chiral Pesticides in Chiral Biological Enciroments: Do We Need to Move Beyond our Achiral Perspective.

EPA Science Inventory

When a chemical stressor crosses the body barrier it becomes an internal dose. In the context of risk assessment, this internal dose provides a critical linkage between exposure and effects. Pharmacokinetic processes (i.e., what the body does to the chemical) such as absorption, ...

Towards Measurements of Chiral Effects Using Identified Particles from STAR

NASA Astrophysics Data System (ADS)

Wen, Liwen; STAR Collaboration

2017-11-01

We report recent STAR results on searching for the Chiral Magnetic Effect via measurements of γ correlation and κK parameter for charged hadrons and identified particle pairs (ππ, pK, πK, pp, pπ) in Au+Au collisions at 200 GeV. We compare the κK parameters with expectations from the AMPT simulations. Sizable γ correlations for charged hadrons, using Time Projection Chamber event plane, in p+Au and d+Au 200 GeV have been observed, and the correlations in these small systems are reduced to near zero when the event planes from forward detectors are used. We will also present our results on the Chiral Magnetic Wave searches from p+Au collisions at 200 GeV.

One-loop perturbative coupling of A and A? through the chiral overlap operator

NASA Astrophysics Data System (ADS)

Makino, Hiroki; Morikawa, Okuto; Suzuki, Hiroshi

2018-03-01

Recently, Grabowska and Kaplan constructed a four-dimensional lattice formulation of chiral gauge theories on the basis of the chiral overlap operator. At least in the tree-level approximation, the left-handed fermion is coupled only to the original gauge field A, while the right-handed one is coupled only to the gauge field A*, a deformation of A by the gradient flow with infinite flow time. In this paper, we study the fermion one-loop effective action in their formulation. We show that the continuum limit of this effective action contains local interaction terms between A and A*, even if the anomaly cancellation condition is met. These non-vanishing terms would lead an undesired perturbative spectrum in the formulation.

Novel topological effects in dense QCD in a magnetic field

NASA Astrophysics Data System (ADS)

Ferrer, E. J.; de la Incera, V.

2018-06-01

We study the electromagnetic properties of dense QCD in the so-called Magnetic Dual Chiral Density Wave phase. This inhomogeneous phase exhibits a nontrivial topology that comes from the fermion sector due to the asymmetry of the lowest Landau level modes. The nontrivial topology manifests in the electromagnetic effective action via a chiral anomaly term θFμνF˜μν, with a dynamic axion field θ given by the phase of the Dual Chiral Density Wave condensate. The coupling of the axion with the electromagnetic field leads to several macroscopic effects that include, among others, an anomalous, nondissipative Hall current, an anomalous electric charge, magnetoelectricity, and the formation of a hybridized propagating mode known as an axion polariton. Connection to topological insulators and Weyls semimetals, as well as possible implications for heavy-ion collisions and neutron stars are all highlighted.

Stereoselectivity in ene reactions with 1O2: matrix effects in polymer supports, photo-oxygenation of organic salts and asymmetric synthesis.

PubMed

Griesbeck, Axel G; Bartoschek, Anna; Neudörfl, Jörg; Miara, Claus

2006-01-01

The ene reaction of chiral allylic alcohols is applied as a tool for the investigation of intrapolymer effects by means of the stereoselectivity of the singlet-oxygen addition. The diastereo selectivity strongly depends on the structure of the polymer, the substrate loading degree and also on the degree of conversion demonstrating additional supramolecular effects evolving during the reaction. The efficiency and the stability of polymer-bound sensitizers were evaluated by the ene reaction of singlet oxygen with citronellol. The ene reaction with chiral ammonium salts of tiglic acid was conducted under solution phase conditions or in polystyrene beads under chiral contact ion-pair conditions. The products thus obtained precipitate during the photoreaction as ammonium salts. Moderate asymmetric induction was observed for this procedure for the first time.

One-loop perturbative coupling of A and A⊙ through the chiral overlap operator

NASA Astrophysics Data System (ADS)

Makino, Hiroki; Morikawa, Okuto; Suzuki, Hiroshi

2017-06-01

We study the one-loop effective action defined by the chiral overlap operator in the four-dimensional lattice formulation of chiral gauge theories by Grabowska and Kaplan. In the tree-level continuum limit, the left-handed component of the fermion is coupled only to the original gauge field A, while the right-handed one is coupled only to A_\\star, which is given by the gradient flow of A with infinite flow time. In this paper, we show that the continuum limit of the one-loop effective action contains local interaction terms between A and A_\\star, which do not generally vanish even if the gauge representation of the fermion is anomaly free. We argue that the presence of such interaction terms can be regarded as undesired gauge symmetry-breaking effects in the formulation.

Quantum Monte Carlo calculations of light nuclei with local chiral two- and three-nucleon interactions

DOE PAGES

Lynn, J. E.; Tews, I.; Carlson, J.; ...

2017-11-30

Local chiral effective field theory interactions have recently been developed and used in the context of quantum Monte Carlo few- and many-body methods for nuclear physics. In this paper, we go over detailed features of local chiral nucleon-nucleon interactions and examine their effect on properties of the deuteron, paying special attention to the perturbativeness of the expansion. We then turn to three-nucleon interactions, focusing on operator ambiguities and their interplay with regulator effects. We then discuss the nuclear Green's function Monte Carlo method, going over both wave-function correlations and approximations for the two- and three-body propagators. Finally, following this, wemore » present a range of results on light nuclei: Binding energies and distribution functions are contrasted and compared, starting from several different microscopic interactions.« less

Anomalous chiral transport in heavy ion collisions from Anomalous-Viscous Fluid Dynamics

NASA Astrophysics Data System (ADS)

Shi, Shuzhe; Jiang, Yin; Lilleskov, Elias; Liao, Jinfeng

2018-07-01

Chiral anomaly is a fundamental aspect of quantum theories with chiral fermions. How such microscopic anomaly manifests itself in a macroscopic many-body system with chiral fermions, is a highly nontrivial question that has recently attracted significant interest. As it turns out, unusual transport currents can be induced by chiral anomaly under suitable conditions in such systems, with the notable example of the Chiral Magnetic Effect (CME) where a vector current (e.g. electric current) is generated along an external magnetic field. A lot of efforts have been made to search for CME in heavy ion collisions, by measuring the charge separation effect induced by the CME transport. A crucial challenge in such effort, is the quantitative prediction for the CME signal. In this paper, we develop the Anomalous-Viscous Fluid Dynamics (AVFD) framework, which implements the anomalous fluid dynamics to describe the evolution of fermion currents in QGP, on top of the neutral bulk background described by the VISH2+1 hydrodynamic simulations for heavy ion collisions. With this new tool, we quantitatively and systematically investigate the dependence of the CME signal to a series of theoretical inputs and associated uncertainties. With realistic estimates of initial conditions and magnetic field lifetime, the predicted CME signal is quantitatively consistent with measured change separation data in 200GeV Au-Au collisions. Based on analysis of Au-Au collisions, we further make predictions for the CME observable to be measured in the planned isobaric (Ru-Ru v.s. Zr-Zr) collision experiment, which could provide a most decisive test of the CME in heavy ion collisions.

Chirality-Controlled Synthesis and Applications of Single-Wall Carbon Nanotubes.

PubMed

Liu, Bilu; Wu, Fanqi; Gui, Hui; Zheng, Ming; Zhou, Chongwu

2017-01-24

Preparation of chirality-defined single-wall carbon nanotubes (SWCNTs) is the top challenge in the nanotube field. In recent years, great progress has been made toward preparing single-chirality SWCNTs through both direct controlled synthesis and postsynthesis separation approaches. Accordingly, the uses of single-chirality-dominated SWCNTs for various applications have emerged as a new front in nanotube research. In this Review, we review recent progress made in the chirality-controlled synthesis of SWCNTs, including metal-catalyst-free SWCNT cloning by vapor-phase epitaxy elongation of purified single-chirality nanotube seeds, chirality-specific growth of SWCNTs on bimetallic solid alloy catalysts, chirality-controlled synthesis of SWCNTs using bottom-up synthetic strategy from carbonaceous molecular end-cap precursors, etc. Recent major progresses in postsynthesis separation of single-chirality SWCNT species, as well as methods for chirality characterization of SWCNTs, are also highlighted. Moreover, we discuss some examples where single-chirality SWCNTs have shown clear advantages over SWCNTs with broad chirality distributions. We hope this review could inspire more research on the chirality-controlled preparation of SWCNTs and equally important inspire the use of single-chirality SWCNT samples for more fundamental studies and practical applications.

6D fractional quantum Hall effect

NASA Astrophysics Data System (ADS)

Heckman, Jonathan J.; Tizzano, Luigi

2018-05-01

We present a 6D generalization of the fractional quantum Hall effect involving membranes coupled to a three-form potential in the presence of a large background four-form flux. The low energy physics is governed by a bulk 7D topological field theory of abelian three-form potentials with a single derivative Chern-Simons-like action coupled to a 6D anti-chiral theory of Euclidean effective strings. We derive the fractional conductivity, and explain how continued fractions which figure prominently in the classification of 6D superconformal field theories correspond to a hierarchy of excited states. Using methods from conformal field theory we also compute the analog of the Laughlin wavefunction. Compactification of the 7D theory provides a uniform perspective on various lower-dimensional gapped systems coupled to boundary degrees of freedom. We also show that a supersymmetric version of the 7D theory embeds in M-theory, and can be decoupled from gravity. Encouraged by this, we present a conjecture in which IIB string theory is an edge mode of a 10 + 2-dimensional bulk topological theory, thus placing all twelve dimensions of F-theory on a physical footing.

Chiral supramolecular organization from a sheet-like achiral gel: a study of chiral photoinduction.

PubMed

Royes, Jorge; Polo, Víctor; Uriel, Santiago; Oriol, Luis; Piñol, Milagros; Tejedor, Rosa M

2017-05-31

Chiral photoinduction in a photoresponsive gel based on an achiral 2D architecture with high geometric anisotropy and low roughness has been investigated. Circularly polarized light (CPL) was used as a chiral source and an azobenzene chromophore was employed as a chiral trigger. The chiral photoinduction was studied by evaluating the preferential excitation of enantiomeric conformers of the azobenzene units. Crystallographic data and density functional theory (DFT) calculations show how chirality is transferred to the achiral azomaterials as a result of the combination of chiral photochemistry and supramolecular interactions. This procedure could be applied to predict and estimate chirality transfer from a chiral physical source to a supramolecular organization using different light-responsive units.

Enhanced chiral response from the Fabry-Perot cavity coupled meta-surfaces

NASA Astrophysics Data System (ADS)

Yang, Ze-Jian; Hu, De-Jiao; Gao, Fu-Hua; Hou, Yi-Dong

2016-08-01

The circular dichroism (CD) signal of a two-dimensional (2D) chiral meta-surface is usually weak, where the difference between the transmitted (or reflected) right and left circular polarization is barely small. We present a general method to enhance the reflective CD spectrum, by adding a layer of reflective film behind the meta-surface. The light passes through the chiral meta-surface and propagates towards the reflector, where it is reflected back and further interacts with the chiral meta-surface. The light is reflected back and forth between these two layers, forming a Fabry-Perot type resonance, which interacts with the localized surface plasmonic resonance (LSPR) mode and greatly enhances the CD signal of the light wave leaving the meta-surface. We numerically calculate the CD enhancing effect of an L-shaped chiral meta-surface on a gold film in the visible range. Compared with the single layer meta-surface, the L-shaped chiral meta-surface has a CD maximum that is dramatically increased to 1. The analysis of reflection efficiency reveals that our design can be used to realize a reflective circular polarizer. Corresponding mode analysis shows that the huge CD originates from the hybrid mode comprised of FP mode and LSPR. Our results provide a general approach to enhancing the CD signal of a chiral meta-surface and can be used in areas like biosensing, circular polarizer, integrated photonics, etc. Project supported by the National Natural Science Foundation of China (Grant No. 61377054).

Effects of molecular asymmetry of optically active molecules on the polarization properties of multiply scattered light

NASA Astrophysics Data System (ADS)

Vitkin, I. Alex; Laszlo, Richard D.; Whyman, Claire L.

2002-02-01

The use of polarized light for investigation of optically turbid systems has generated much recent interest since it has been shown that multiple scattering does not fully scramble the incident polarization states. It is possible under some conditions to measure polarization signals in diffusely scattered light, and use this information to characterize the structure or composition of the turbid medium. Furthermore, the idea of quantitative detection of optically active (chiral) molecules contained in such a system is attractive, particularly in clinical medicine where it may contribute to the development of a non-invasive method of glucose sensing in diabetic patients. This study uses polarization modulation and synchronous detection in the perpendicular and in the exact backscattering orientations to detect scattered light from liquid turbid samples containing varying amounts of L and D (left and right) isomeric forms of a chiral sugar. Polarization preservation increased with chiral concentrations in both orientations. In the perpendicular orientation, the optical rotation of the linearly polarized fraction also increased with the concentration of chiral solute, but in different directions for the two isomeric forms. There was no observed optical rotation in the exact backscattering geometry for either isomer. The presence of the chiral species is thus manifest in both detection directions, but the sense of the chiral asymmetry is not resolvable in retroreflection. The experiments show that useful information may be extracted from turbid chiral samples using polarized light.

Hierarchical chirality transfer in the growth of Towel Gourd tendrils

PubMed Central

Wang, Jian-Shan; Wang, Gang; Feng, Xi-Qiao; Kitamura, Takayuki; Kang, Yi-Lan; Yu, Shou-Wen; Qin, Qing-Hua

2013-01-01

Chirality plays a significant role in the physical properties and biological functions of many biological materials, e.g., climbing tendrils and twisted leaves, which exhibit chiral growth. However, the mechanisms underlying the chiral growth of biological materials remain unclear. In this paper, we investigate how the Towel Gourd tendrils achieve their chiral growth. Our experiments reveal that the tendrils have a hierarchy of chirality, which transfers from the lower levels to the higher. The change in the helical angle of cellulose fibrils at the subcellular level induces an intrinsic torsion of tendrils, leading to the formation of the helical morphology of tendril filaments. A chirality transfer model is presented to elucidate the chiral growth of tendrils. This present study may help understand various chiral phenomena observed in biological materials. It also suggests that chirality transfer can be utilized in the development of hierarchically chiral materials having unique properties. PMID:24173107

Direct Detection of Hardly Detectable Hidden Chirality of Hydrocarbons and Deuterated Isotopomers by a Helical Polyacetylene through Chiral Amplification and Memory.

PubMed

Maeda, Katsuhiro; Hirose, Daisuke; Okoshi, Natsuki; Shimomura, Kouhei; Wada, Yuya; Ikai, Tomoyuki; Kanoh, Shigeyoshi; Yashima, Eiji

2018-03-07

We report the first direct chirality sensing of a series of chiral hydrocarbons and isotopically chiral compounds (deuterated isotopomers), which are almost impossible to detect by conventional optical spectroscopic methods, by a stereoregular polyacetylene bearing 2,2'-biphenol-derived pendants. The polyacetylene showed a circular dichroism due to a preferred-handed helix formation in response to the hardly detectable hidden chirality of saturated tertiary or chiroptical quaternary hydrocarbons, and deuterated isotopomers. In sharp contrast to the previously reported sensory systems, the chirality detection by the polyacetylene relies on an excess one-handed helix formation induced by the chiral hydrocarbons and deuterated isotopomers via significant amplification of the chirality followed by its static memory, through which chiral information on the minute and hidden chirality can be stored as an excess of a single-handed helix memory for a long time.

Chiral Recognition and Separation by Chirality-Enriched Metal-Organic Frameworks.

PubMed

Das, Saikat; Xu, Shixian; Ben, Teng; Qiu, Shilun

2018-05-16

Endowed with chiral channels and pores, chiral metal-organic frameworks (MOFs) are highly useful; however, their synthesis remains a challenge given that most chiral building blocks are expensive. Although MOFs with induced chirality have been reported to avoid this shortcoming, no study providing evidence for the ee value of such MOFs has yet been reported. We herein describe the first study on the efficiency of chiral induction in MOFs using inexpensive achiral building blocks and fully recoverable chiral dopants to control the handedness of racemic MOFs. This method yielded chirality-enriched MOFs with accessible pores. The ability of the materials to form host-guest complexes was probed with enantiomers of varying size and coordination and in solvents with varying polarity. Furthermore, mixed-matrix membranes (MMMs) composed of chirality-enriched MOF particles dispersed in a polymer matrix demonstrated a new route for chiral separation. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Utilization of Alternate Chirality Enantiomers in Microbial Communities

NASA Technical Reports Server (NTRS)

Pikuta, Elena V.; Hoover, Richard B.

2010-01-01

Our previous study of chirality led to interesting findings for some anaerobic extremophiles: the ability to metabolize substrates with alternate chirality enantiomers of amino acids and sugars. We have subsequently found that not just separate microbial species or strains but entire microbial communities have this ability. The functional division within a microbial community on proteo- and sugarlytic links was also reflected in a microbial diet with L-sugars and D-amino acids. Several questions are addressed in this paper. Why and when was this feature developed in a microbial world? Was it a secondary de novo adaptation in a bacterial world? Or is this a piece of genetic information that has been left in modern genomes as an atavism? Is it limited exclusively to prokaryotes, or does this ability also occur in eukaryotes? In this article, we have used a broader approach to study this phenomenon using anaerobic extremophilic strains from our laboratory collection. A series of experiments were performed on physiologically different groups of extremophilic anaerobes (pure and enrichment cultures). The following characteristics were studied: 1) the ability to grow on alternate chirality enantiomers -- L-sugars and D- amino acids; 2) Growth-inhibitory effect of alternate chirality enantiomers; 3) Stickland reaction with alternate chirality amino acids. The results of this research are presented in this paper.

Fabrication of chiroptically switchable films via co-gelation of a small chiral gelator with an achiral azobenzene-containing polymer.

PubMed

Yang, Dong; Zhang, Li; Yin, Lu; Zhao, Yin; Zhang, Wei; Liu, Minghua

2017-09-20

Helical polymers are widely found in nature and synthetic functional materials. Although a number of elaborate strategies have been developed to endow polymers with helicity through either covalent bonds or supramolecular techniques, it still remains a challenge to get the desired helical polymers with controlled handedness in an easy but effective manner. In this study, we report an easily accessible gelation-guided self-assembly system where the chirality of a gelator can be easily transferred to an achiral azobenzene-containing polymer during gelation. It is found that during the process of chiral induction, the induced chirality of the polymer was entirely dominated by the molecular chirality of the gelator. Experimentally, achiral azobenzene-containing polymers with different side-chain lengths were doped into a supramolecular gel system formed with amphiphilic N,N'-bis-(octadecyl)-l(d)-Boc-glutamic (LBG-18 or DBG-18 for short). CD spectra and SEM observation confirmed that the co-assembly of polymer/LBG-18 or polymer/DBG-18 in the xerogel state exhibited supramolecular chirality. More importantly, alternate UV and visible light irradiation on the xerogel film caused the induced CD signal to switch between on and off states. Thus a chiroptical switch was fabricated based on the isomerization of the azo-polymer in xerogel films.

Chirality-sensitive microwave spectroscopy - application to terpene molecules

NASA Astrophysics Data System (ADS)

Schnell, Melanie

Most molecules of biochemical relevance are chiral. Even though the physical properties of two enantiomers are nearly identical, they might exhibit completely different biochemical effects, such as different odor in the case of carvone. In nature and as products of chemical syntheses, chiral molecules often exist in mixtures with other chiral molecules. The analysis of these complex mixtures to identify the molecular components, to determine which enantiomers are present, and to measure the enantiomeric excesses (ee) is still one of the challenging and very important tasks of analytical chemistry. We recently experimentally demonstrated a new method of differentiating enantiomeric pairs of chiral molecules in the gas phase. It is based on broadband rotational spectroscopy and is a three-wave mixing process that involves a closed cycle of three rotational transitions. The phase of the acquired signal bares the signature of the enantiomer, as it depends upon the product of the transition dipole moments. Furthermore, because the signal amplitude is proportional to the ee, this technique allows not only for determining which enantiomer is in excess, but also by how much. A unique advantage of our technique is that it can also be applied to mixtures of chiral molecules, even when the molecules are very similar. In my lecture, I will introduce the technique and give an update on the recent developments.

Light-Nuclei Spectra from Chiral Dynamics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piarulli, M.; Baroni, A.; Girlanda, L.

In recent years local chiral interactions have been derived and implemented in quantum Monte Carlo methods in order to test to what extent the chiral effective field theory framework impacts our knowledge of few- and many-body systems. Here in this Letter, we present Green’s function Monte Carlo calculations of light nuclei based on the family of local two-body interactions presented by our group in a previous paper in conjunction with chiral three-body interactions fitted to bound- and scattering-state observables in the three-nucleon sector. These interactions include Δ intermediate states in their two-pion-exchange components. We obtain predictions for the energy levelsmore » and level ordering of nuclei in the mass range A=4–12, accurate to ≤2% of the binding energy, in very satisfactory agreement with experimental data.« less

Dissipative vibrational model for chiral recognition in olfaction

NASA Astrophysics Data System (ADS)

Tirandaz, Arash; Taher Ghahramani, Farhad; Shafiee, Afshin

2015-09-01

We examine the olfactory discrimination of left- and right-handed enantiomers of chiral odorants based on the odorant-mediated electron transport from a donor to an acceptor of the olfactory receptors embodied in a biological environment. The chiral odorant is effectively described by an asymmetric double-well potential whose minima are associated to the left- and right-handed enantiomers. The introduced asymmetry is considered an overall measure of chiral interactions. The biological environment is conveniently modeled as a bath of harmonic oscillators. The resulting spin-boson model is adapted by a polaron transformation to derive the corresponding Born-Markov master equation with which we obtain the elastic and inelastic electron tunneling rates. We show that the inelastic tunneling through left- and right-handed enantiomers occurs with different rates. The discrimination mechanism depends on the ratio of tunneling frequency to localization frequency.

Light-Nuclei Spectra from Chiral Dynamics

DOE PAGES

Piarulli, M.; Baroni, A.; Girlanda, L.; ...

2018-02-01

In recent years local chiral interactions have been derived and implemented in quantum Monte Carlo methods in order to test to what extent the chiral effective field theory framework impacts our knowledge of few- and many-body systems. Here in this Letter, we present Green’s function Monte Carlo calculations of light nuclei based on the family of local two-body interactions presented by our group in a previous paper in conjunction with chiral three-body interactions fitted to bound- and scattering-state observables in the three-nucleon sector. These interactions include Δ intermediate states in their two-pion-exchange components. We obtain predictions for the energy levelsmore » and level ordering of nuclei in the mass range A=4–12, accurate to ≤2% of the binding energy, in very satisfactory agreement with experimental data.« less

Structural and electronic properties of chiral single-wall copper nanotubes

NASA Astrophysics Data System (ADS)

Duan, YingNi; Zhang, JianMin; Xu, KeWei

2014-04-01

The structural, energetic and electronic properties of chiral ( n, m) (3⩽ n⩽6, n/2⩽ m⩽ n) single-wall copper nanotubes (CuNTs) have been investigated by using projector-augmented wave method based on density-functional theory. The (4, 3) CuNT is energetically stable and should be observed experimentally in both free-standing and tip-suspended conditions, whereas the (5, 5) and (6, 4) CuNTs should be observed in free-standing and tip-suspended conditions, respectively. The number of conductance channels in the CuNTs does not always correspond to the number of atomic strands comprising the nanotube. Charge density contours show that there is an enhanced interatomic interaction in CuNTs compared with Cu bulk. Current transporting states display different periods and chirality, the combined effects of which lead to weaker chiral currents on CuNTs.

Individual eigenvalue distributions of crossover chiral random matrices and low-energy constants of SU(2) × U(1) lattice gauge theory

NASA Astrophysics Data System (ADS)

Yamamoto, Takuya; Nishigaki, Shinsuke M.

2018-02-01

We compute individual distributions of low-lying eigenvalues of a chiral random matrix ensemble interpolating symplectic and unitary symmetry classes by the Nyström-type method of evaluating the Fredholm Pfaffian and resolvents of the quaternion kernel. The one-parameter family of these distributions is shown to fit excellently the Dirac spectra of SU(2) lattice gauge theory with a constant U(1) background or dynamically fluctuating U(1) gauge field, which weakly breaks the pseudoreality of the unperturbed SU(2) Dirac operator. The observed linear dependence of the crossover parameter with the strength of the U(1) perturbations leads to precise determination of the pseudo-scalar decay constant, as well as the chiral condensate in the effective chiral Lagrangian of the AI class.

Compound analysis via graph kernels incorporating chirality.

PubMed

Brown, J B; Urata, Takashi; Tamura, Takeyuki; Arai, Midori A; Kawabata, Takeo; Akutsu, Tatsuya

2010-12-01

High accuracy is paramount when predicting biochemical characteristics using Quantitative Structural-Property Relationships (QSPRs). Although existing graph-theoretic kernel methods combined with machine learning techniques are efficient for QSPR model construction, they cannot distinguish topologically identical chiral compounds which often exhibit different biological characteristics. In this paper, we propose a new method that extends the recently developed tree pattern graph kernel to accommodate stereoisomers. We show that Support Vector Regression (SVR) with a chiral graph kernel is useful for target property prediction by demonstrating its application to a set of human vitamin D receptor ligands currently under consideration for their potential anti-cancer effects.

Chiral Brønsted Acid-Catalyzed Allylboration of Aldehydes

PubMed Central

Jain, Pankaj; Antilla, Jon C.

2010-01-01

The catalytic enantioselective allylation of aldehydes is a long-standing problem with considerable interest to the chemical community. We wish to disclose a new high yielding and highly enantioselective chiral Brønsted acid-catalyzed allylboration of aldehydes. The reaction is shown to be highly general, with broad substrate scope that covers aryl, heteroaryl, α,β-unsaturated, and aliphatic aldehydes. The reaction conditions were also shown to be effective for the catalytic enantioselective crotylation of aldehydes. We believe that the high reactivity of the allyl boronate is due to protonation of the boronate oxygen by the chiral phosphoric acid catalyst. PMID:20690662

Highly efficient all-dielectric optical tensor impedance metasurfaces for chiral polarization control.

PubMed

Kim, Minseok; Eleftheriades, George V

2016-10-15

We propose a highly efficient (nearly lossless and impedance-matched) all-dielectric optical tensor impedance metasurface that mimics chiral effects at optical wavelengths. By cascading an array of rotated crossed silicon nanoblocks, we realize chiral optical tensor impedance metasurfaces that operate as circular polarization selective surfaces. Their efficiencies are maximized through a nonlinear numerical optimization process in which the tensor impedance metasurfaces are modeled via multi-conductor transmission line theory. From rigorous full-wave simulations that include all material losses, we show field transmission efficiencies of 94% for right- and left-handed circular polarization selective surfaces at 800 nm.

A Helicene Nanoribbon with Greatly Amplified Chirality.

PubMed

Schuster, Nathaniel J; Hernández Sánchez, Raúl; Bukharina, Daria; Kotov, Nicholas A; Berova, Nina; Ng, Fay; Steigerwald, Michael L; Nuckolls, Colin

2018-05-14

We report the synthesis and characterization of a chiral, shape-persistent, perylene-diimide-based nanoribbon. Specifically, the fusion of three perylene-diimide monomers with intervening naphthalene subunits resulted in a helical superstructure with two [6]helicene subcomponents. This π-helix-of-helicenes exhibits very intense electronic circular dichroism, including one of the largest Cotton effects ever observed in the visible range. It also displays more than an order of magnitude increase in circular dichroism for select wavelengths relative to its smaller homologue. These impressive chiroptical properties underscore the potential of this new nanoribbon architecture in the context of chiral electronic materials.

Omnidirectional narrow optical filters for circularly polarized light in a nanocomposite structurally chiral medium.

PubMed

Avendaño, Carlos G; Palomares, Laura O

2018-04-20

We consider the propagation of electromagnetic waves throughout a nanocomposite structurally chiral medium consisting of metallic nanoballs randomly dispersed in a structurally chiral material whose dielectric properties can be represented by a resonant effective uniaxial tensor. It is found that an omnidirectional narrow pass band and two omnidirectional narrow band gaps are created in the blue optical spectrum for right and left circularly polarized light, as well as narrow reflection bands for right circularly polarized light that can be controlled by varying the light incidence angle and the filling fraction of metallic inclusions.

A C–H oxidation approach for streamlining synthesis of chiral polyoxygenated motifs

PubMed Central

Covell, Dustin J.; White, M. Christina

2013-01-01

Chiral oxygenated molecules are pervasive in natural products and medicinal agents; however, their chemical syntheses often necessitate numerous, wasteful steps involving functional group and oxidation state manipulations. Herein a strategy for synthesizing a readily diversifiable class of chiral building blocks, allylic alcohols, through sequential asymmetric C—H activation/resolution is evaluated against the state-of-the-art. The C—H oxidation routes’ capacity to strategically introduce oxygen into a sequence and thereby minimize non-productive manipulations is demonstrated to effect significant decreases in overall step-count and increases in yield and synthetic flexibility. PMID:25013239

The scalar and electromagnetic form factors of the nucleon in dispersively improved Chiral EFT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alarcon, Jose Manuel

We present a method for calculating the nucleon form factors of G-parity-even operators. This method combines chiral effective field theory (χEFT) and dispersion theory. Through unitarity we factorize the imaginary part of the form factors into a perturbative part, calculable with χEFT, and a non-perturbative part, obtained through other methods. We consider the scalar and electromagnetic (EM) form factors of the nucleon. The results show an important improvement compared to standard chiral calculations, and can be used in analysis of the low-energy properties of the nucleon.

d +i d chiral superconductivity in a triangular lattice from trigonal bipyramidal complexes

NASA Astrophysics Data System (ADS)

Lu, Chen; Zhang, Li-Da; Wu, Xianxin; Yang, Fan; Hu, Jiangping

2018-04-01

We model the newly predicted high-Tc superconducting candidates constructed by corner-shared trigonal bipyramidal complexes with an effective three-orbital tight-binding Hamiltonian and investigate the pairing symmetry of their superconducting states driven by electron-electron interactions. Our combined weak- and strong-coupling-based calculations consistently identify the chiral d +i d superconductivity as the leading pairing symmetry in a wide doping range with realistic interaction parameters. This pairing state has a nontrivial topological Chern number and can host gapless chiral edge modes, and the vortex cores under magnetic field can carry Majorana zero modes.

Neutron matter with Quantum Monte Carlo: chiral 3N forces and static response

DOE PAGES

Buraczynski, M.; Gandolfi, S.; Gezerlis, A.; ...

2016-03-14

Neutron matter is related to the physics of neutron stars and that of neutron-rich nuclei. Moreover, Quantum Monte Carlo (QMC) methods offer a unique way of solving the many-body problem non-perturbatively, providing feedback on features of nuclear interactions and addressing scenarios that are inaccessible to other approaches. Our contribution goes over two recent accomplishments in the theory of neutron matter: a) the fusing of QMC with chiral effective field theory interactions, focusing on local chiral 3N forces, and b) the first attempt to find an ab initio solution to the problem of static response.

Dynamic amplification of light signals in photorefractive ferroelectric liquid crystal blends containing photoconductive chiral dopant

NASA Astrophysics Data System (ADS)

Sasaki, T.; Hafuri, M.; Suda, T.; Nakano, M.; Funada, K.; Ohta, M.; Terazono, T.; Le, K. V.; Naka, Y.

2017-08-01

Effect of ferroelectricity on the photorefractive effect of ferroelectric liquid crystal blends was investigated. The photorefractive effect of ferroelectric liquid crystal blends strongly depend on the ferroelectricity of the blend. We have prepared a series of ferroelectric liquid crystal blends that contains several concentrations of a chiral compound while keeping a constant concentration of a photoconductive moiety. The photorefractive properties of the ferroelectric liquid crystal blends were discussed with relations to the ferroelectric properties of the blends.

Combined effects of nonparaxiality, optical activity, and walk-off on rogue wave propagation in optical fibers filled with chiral materials.

PubMed

Temgoua, D D Estelle; Tchokonte, M B Tchoula; Kofane, T C

2018-04-01

The generalized nonparaxial nonlinear Schrödinger (NLS) equation in optical fibers filled with chiral materials is reduced to the higher-order integrable Hirota equation. Based on the modified Darboux transformation method, the nonparaxial chiral optical rogue waves are constructed from the scalar model with modulated coefficients. We show that the parameters of nonparaxiality, third-order dispersion, and differential gain or loss term are the main keys to control the amplitude, linear, and nonlinear effects in the model. Moreover, the influence of nonparaxiality, optical activity, and walk-off effect are also evidenced under the defocusing and focusing regimes of the vector nonparaxial NLS equations with constant and modulated coefficients. Through an algorithm scheme of wider applicability on nonparaxial beam propagation methods, the most influential effect and the simultaneous controllability of combined effects are underlined, showing their properties and their potential applications in optical fibers and in a variety of complex dynamical systems.

Combined effects of nonparaxiality, optical activity, and walk-off on rogue wave propagation in optical fibers filled with chiral materials

NASA Astrophysics Data System (ADS)

Temgoua, D. D. Estelle; Tchokonte, M. B. Tchoula; Kofane, T. C.

2018-04-01

The generalized nonparaxial nonlinear Schrödinger (NLS) equation in optical fibers filled with chiral materials is reduced to the higher-order integrable Hirota equation. Based on the modified Darboux transformation method, the nonparaxial chiral optical rogue waves are constructed from the scalar model with modulated coefficients. We show that the parameters of nonparaxiality, third-order dispersion, and differential gain or loss term are the main keys to control the amplitude, linear, and nonlinear effects in the model. Moreover, the influence of nonparaxiality, optical activity, and walk-off effect are also evidenced under the defocusing and focusing regimes of the vector nonparaxial NLS equations with constant and modulated coefficients. Through an algorithm scheme of wider applicability on nonparaxial beam propagation methods, the most influential effect and the simultaneous controllability of combined effects are underlined, showing their properties and their potential applications in optical fibers and in a variety of complex dynamical systems.

Recent progress of chiral stationary phases for separation of enantiomers in gas chromatography.

PubMed

Xie, Sheng-Ming; Yuan, Li-Ming

2017-01-01

Chromatography techniques based on chiral stationary phases are widely used for the separation of enantiomers. In particular, gas chromatography has developed rapidly in recent years due to its merits such as fast analysis speed, lower consumption of stationary phases and analytes, higher column efficiency, making it a better choice for chiral separation in diverse industries. This article summarizes recent progress of novel chiral stationary phases based on cyclofructan derivatives and chiral porous materials including chiral metal-organic frameworks, chiral porous organic frameworks, chiral inorganic mesoporous materials, and chiral porous organic cages in gas chromatography, covering original research papers published since 2010. The chiral recognition properties and mechanisms of separation toward enantiomers are also introduced. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Complex topological structures of frustrated liquid crystals with potential for optics and photonics (Presentation Recording)

NASA Astrophysics Data System (ADS)

Žumer, Slobodan; Čančula, Miha; Čopar, Simon; Ravnik, Miha

2015-10-01

Geometrical constrains and intrinsic chirality in nematic mesophases enable formation of stable and metastable complex defect structures. Recently selected knotted and linked disclinations have been formed using laser manipulation of nematic braids entangling colloidal particles in nematic colloids [Tkalec et al., Science 2011; Copar et al., PNAS 2015]. In unwinded chiral nematic phases stable and metastable toron and hopfion defects have been implemented by laser tweezers [Smalyukh et al., Nature Materials 2010; Chen et al., PRL2013] and in chiral nematic colloids particles dressed by solitonic deformations [Porenta et al., Sci. Rep. 2014]. Modelling studies based on the numerical minimisation of the phenomenological free energy, supported with the adapted topological theory [Copar and Zumer, PRL 2011; Copar, Phys. Rep. 2014] allow describing the observed nematic defect structures and also predicting numerous structures in confined blue phases [Fukuda and Zumer, Nature Comms 2011 and PRL 2011] and stable knotted disclinations in cholesteric droplets with homeotropic boundary [Sec et al., Nature Comms 2014]. Coupling the modeling with finite difference time domain light field computation enables understanding of light propagation and light induced restructuring in these mesophases. The method was recently demonstrated for the description of low intensity light beam changes during the propagation along disclination lines [Brasselet et al., PRL 2009; Cancula et al., PRE 2014]. Allowing also high intensity light an order restructuring is induced [Porenta et al., Soft Matter 2012; Cancula et al., 2015]. These approaches help to uncover the potential of topological structures for beyond-display optical and photonic applications.

Highly Efficient Chirality Transfer from Diamines Encapsulated within a Self-Assembled Calixarene-Salen Host.

PubMed

Martínez-Rodríguez, Luis; Bandeira, Nuno A G; Bo, Carles; Kleij, Arjan W

2015-05-04

A calix[4]arene host equipped with two bis-[Zn(salphen)] complexes self-assembles into a capsular complex in the presence of a chiral diamine guest with an unexpected 2:1 ratio between the host and the guest. Effective chirality transfer from the diamine to the calix-salen hybrid host is observed by circular dichroism (CD) spectroscopy, and a high stability constant K2,1 of 1.59×10(11)  M(-2) for the assembled host-guest ensemble has been determined with a substantial cooperativity factor α of 6.4. Density functional calculations are used to investigate the origin of the stability of the host-guest system and the experimental CD spectrum compared with those calculated for both possible diastereoisomers showing that the M,M isomer is the one that is preferentially formed. The current system holds promise for the chirality determination of diamines, as evidenced by the investigated substrate scope and the linear relationship between the ee of the diamine and the amplitude of the observed Cotton effects. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Weyl magnons in noncoplanar stacked kagome antiferromagnets

NASA Astrophysics Data System (ADS)

Owerre, S. A.

2018-03-01

Weyl nodes have been experimentally realized in photonic, electronic, and phononic crystals. However, magnonic Weyl nodes are yet to be seen experimentally. In this paper, we propose Weyl magnon nodes in noncoplanar stacked frustrated kagome antiferromagnets, naturally available in various real materials. Most crucially, the Weyl nodes in the current system occur at the lowest excitation and possess a topological thermal Hall effect, therefore they are experimentally accessible at low temperatures due to the population effect of bosonic quasiparticles. In stark contrast to other magnetic systems, the current Weyl nodes do not rely on time-reversal symmetry breaking by the magnetic order. Rather, they result from explicit macroscopically broken time reversal symmetry by the scalar spin chirality of noncoplanar spin textures and can be generalized to chiral spin liquid states. Moreover, the scalar spin chirality gives a real space Berry curvature which is not available in previously studied magnetic Weyl systems. We show the existence of magnon arc surface states connecting projected Weyl magnon nodes on the surface Brillouin zone. We also uncover the first realization of triply-degenerate nodal magnon point in the noncollinear regime with zero scalar spin chirality.

Search for the Chiral Magnetic Effect in Heavy-Ion Collisions and Quantification of the Background with the AMPT Model

NASA Astrophysics Data System (ADS)

Bryon, Jacob

2017-09-01

The chiral magnetic effect (CME) arises from the chirality imbalance of quarks and its interaction to the strong magnetic field generated in non-central heavy-ion collisions. Possible formation of domains of quarks with chirality imbalances is an intrinsic property of the Quantum ChromoDynamics (QCD), which describes the fundamental strong interactions among quarks and gluons. Azimuthal-angle correlations have been used to measure the magnitude of charge- separation across the reaction plane, which was predicted to arise from the CME. However, backgrounds from collective motion (flow) of the collision system can also contribute to the correlation observable. In this poster, we investigate the magnitude of the background utilizing the AMPT model, which contains no CME signals. We demonstrate, for Au +Au collisions at 200 and 39 GeV, a scheme to remove the flow background via the event-shape engineering with the vanishing magnitude of the flow vector. We also calculate the ensemble average of the charge-separation observable, and provide a background baseline for the experimental data.

Self-Assemblies of Single-Walled Carbon Nanotubes through Tunable Tethering of Pyrenes by Dextrin for Rapidly Chiral Sensing

PubMed Central

Wei, Wei-Li; Chen, Qiushui; Li, Haifang; Lin, Jin-Ming

2011-01-01

Pyrene-modified dextrin (Py-Dex) was synthesized via the Schiff base reaction between reducing end of dextrins and 1-aminopyrene, and then self-assemblies of single-walled carbon nanotubes (SWNTs) were fabricated through the tunable tethering of pyrene to SWNTs by dextrin chains. The Py-Dex-SWNTs assemblies were found to be significantly water-soluble because of the synergistic effect of dextrin chains and pyrene moieties. Py-Dex and Py-Dex-SWNTs were adequately characterized by NMR, UV-vis, fluorescence spectroscopy, Raman spectroscopy, matrix-assisted laser desorption/ionization-time of flight mass spectroscopy, and transmission electron microscopy. The tethering effect of dextrin toward pyrene moieties was clearly revealed and was found to be tunable by adjusting the length of dextrin chains. The fluorescence of pyrene moieties was sufficiently quenched by SWNTs with the support of dextrin chains. Furthermore, the Py-Dex-SWNTs assemblies were used for chiral selective sensing by introducing cyclodextrins as chiral binding sites. The rapid chiral sensing was successfully tested for different enantiomers. PMID:21811502

Meson properties at finite temperature in a three flavor nonlocal chiral quark model with Polyakov loop

DOE Office of Scientific and Technical Information (OSTI.GOV)

Contrera, G. A.; CONICET, Rivadavia 1917, 1033 Buenos Aires; Dumm, D. Gomez

2010-03-01

We study the finite temperature behavior of light scalar and pseudoscalar meson properties in the context of a three-flavor nonlocal chiral quark model. The model includes mixing with active strangeness degrees of freedom, and takes care of the effect of gauge interactions by coupling the quarks with the Polyakov loop. We analyze the chiral restoration and deconfinement transitions, as well as the temperature dependence of meson masses, mixing angles and decay constants. The critical temperature is found to be T{sub c{approx_equal}}202 MeV, in better agreement with lattice results than the value recently obtained in the local SU(3) PNJL model. Itmore » is seen that above T{sub c} pseudoscalar meson masses get increased, becoming degenerate with the masses of their chiral partners. The temperatures at which this matching occurs depend on the strange quark composition of the corresponding mesons. The topological susceptibility shows a sharp decrease after the chiral transition, signalling the vanishing of the U(1){sub A} anomaly for large temperatures.« less

Chiral mirror and optical resonator designs for circularly polarized light: suppression of cross-polarized reflectances and transmittances

NASA Astrophysics Data System (ADS)

Hodgkinson, Ian J.; Wu, Qi h.; Arnold, Matthew; McCall, Martin W.; Lakhtakia, Akhlesh

2002-09-01

A left-handed chiral sculptured thin film (STF) that reflects strongly at the wavelength of the circular Bragg resonance tends to partially convert the handedness of incident LCP (left-circularly-polarized) light to RCP (right-circularly-polarized). We show that the cross-polarized component of the reflected RCP beam can be eliminated by interference with an additional RCP beam that is reflected at the interface of an isotropic cover and an AR (antireflecting) layer. For best results the refractive index and thickness of the AR layer need to accommodate a phase change on reflection that occurs at the chiral film. Effective suppression of the reflectances RRR, RRL, RLR and the transmittances TRL, TLR can be achieved by sandwiching the chiral reflector between such amplitude and phase-matched AR coatings. Co-polarized chiral reflectors of this type may form efficient handed optical resonators. For LCP light the optical properties of such a handed resonator are formally the same as the properties of the isotropic passive or active Fabry-Perot resonators, but the handed resonator is transparent to RCP light.

Chirality of the cytoskeleton in the origins of cellular asymmetry

PubMed Central

2016-01-01

Self-assembly of two important components of the cytoskeleton of eukaryotic cells, actin microfilaments and microtubules (MTs) results in polar filaments of one chirality. As is true for bacterial flagella, in actin microfilaments, screw direction is important for assembly processes and motility. For MTs, polar orientation within the cell is paramount. The alignment of these elements in the cell cytoplasm gives rise to emergent properties, including the potential for cell differentiation and specialization. Complex MTs with a characteristic chirality are found in basal bodies and centrioles; this chirality is preserved in cilia. In motile cilia, it is reflected in the direction of the effective stroke. The positioning of the basal body or cilia on the cell surface depends on polarity proteins. In evolution, survival depends on global polarity information relayed to the cell in part by orientation of the MT and actin filament cytoskeletons and the chirality of the basal body to determine left and right coordinates within a defined anterior–posterior cell and tissue axis. This article is part of the themed issue ‘Provocative questions in left–right asymmetry’. PMID:27821520

Chiral current generation in QED by longitudinal photons

NASA Astrophysics Data System (ADS)

Acosta Avalo, J. L.; Pérez Rojas, H.

2016-08-01

We report the generation of a pseudovector electric current having imbalanced chirality in an electron-positron strongly magnetized gas in QED. It propagates along the external applied magnetic field B as a chiral magnetic effect in QED. It is triggered by a perturbative electric field parallel to B, associated to a pseudovector longitudinal mode propagating along B. An electromagnetic chemical potential was introduced, but our results remain valid even when it vanishes. A nonzero fermion mass was assumed, which is usually considered vanishing in the literature. In the quantum field theory formalism at finite temperature and density, an anomaly relation for the axial current was found for a medium of massive fermions. It bears some analogy to the Adler-Bell-Jackiw anomaly. From the expression for the chiral current in terms of the photon self-energy tensor in a medium, it is obtained that electrons and positrons scattered by longitudinal photons (inside the light cone) contribute to the chiral current, as well as the to pair creation due to longitudinal photons (out of light cone). In the static limit, an electric pseudovector current is obtained in the lowest Landau level.

Topology in the SU(Nf) chiral symmetry restored phase of unquenched QCD and axion cosmology

NASA Astrophysics Data System (ADS)

Azcoiti, Vicente

2018-03-01

The axion is one of the more interesting candidates to make the dark matter of the universe, and the axion potential plays a fundamental role in the determination of the dynamics of the axion field. Moreover, the way in which the U(1)A anomaly manifests itself in the chiral symmetry restored phase of QCD at high temperature could be tested when probing the QCD phase transition in relativistic heavy ion collisions. With these motivations, we investigate the physical consequences of the survival of the effects of the U(1)A anomaly in the chiral symmetric phase of QCD, and show that the free energy density is a singular function of the quark mass m, in the chiral limit, and that the σ and π susceptibilities diverge in this limit at any T ≥ Tc. We also show that the difference between the π and t;δ susceptibilities diverges in the chiral limit at any T ≥ Tc, a result that can be contrasted with the existing lattice calculations; and discuss on the generalization of these results to the Nf ≥ 3 model.

Amino Acid Chirality and Ferrocene Conformation Guided Self-Assembly and Gelation of Ferrocene-Peptide Conjugates.

PubMed

Adhikari, Bimalendu; Singh, Charanpreet; Shah, Afzal; Lough, Alan J; Kraatz, Heinz-Bernhard

2015-08-03

The self-assembly and gelation behavior of a series of mono- and disubstituted ferrocene (Fc)-peptide conjugates as a function of ferrocene conformation and amino acid chirality are described. The results reveal that ferrocene-peptide conjugates self-assemble into organogels by controlling the conformation of the central ferrocene core, through inter- versus intramolecular hydrogen bonding in the attached peptide chain(s). The chirality controlled assembling studies showed that two monosubstituted Fc conjugates FcCO-LFLFLA-OMe and FcCO-LFLFDA-OMe form gels with nanofibrillar network structures, whereas the other two diastereomers FcCO-DFLFLA-OMe and FcCO-LFDFLA-OMe exclusively produced straight nanorods and non-interconnected small fibers, respectively. This suggests the potential tuning of gelation behavior and nanoscale morphology by altering the chirality of constituted amino acids. The current study confirms the profound effect of diastereomerism and no influence of enantiomers on gelation. Correspondingly, the diastereomeric and enantiomeric Fc[CO-FFA-OMe]2 were constructed for the study of chirality-organized structures. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chiral twist drives raft formation and organization in membranes composed of rod-like particles

PubMed Central

Lubensky, Tom C.

2017-01-01

Lipid rafts are hypothesized to facilitate protein interaction, tension regulation, and trafficking in biological membranes, but the mechanisms responsible for their formation and maintenance are not clear. Insights into many other condensed matter phenomena have come from colloidal systems, whose micron-scale particles mimic basic properties of atoms and molecules but permit dynamic visualization with single-particle resolution. Recently, experiments showed that bidisperse mixtures of filamentous viruses can self-assemble into colloidal monolayers with thermodynamically stable rafts exhibiting chiral structure and repulsive interactions. We quantitatively explain these observations by modeling the membrane particles as chiral liquid crystals. Chiral twist promotes the formation of finite-sized rafts and mediates a repulsion that distributes them evenly throughout the membrane. Although this system is composed of filamentous viruses whose aggregation is entropically driven by dextran depletants instead of phospholipids and cholesterol with prominent electrostatic interactions, colloidal and biological membranes share many of the same physical symmetries. Chiral twist can contribute to the behavior of both systems and may account for certain stereospecific effects observed in molecular membranes. PMID:27999184

Possible formation of high temperature superconductor at an early stage of heavy-ion collisions

NASA Astrophysics Data System (ADS)

Liu, Hao; Yu, Lang; Chernodub, Maxim; Huang, Mei

2016-12-01

We investigate the effect of the inverse magnetic catalysis (IMC) on charged ρ meson condensation at finite temperature in the framework of the Nambu-Jona-Lasinio model, where mesons are calculated to the leading order of 1 /Nc expansion. The IMC for chiral condensate has been considered using three different approaches: incorporating the chiral condensate from lattice data, using the running coupling constant, and introducing the chiral chemical potential, respectively. It is observed that with no IMC effect included, the critical magnetic field e Bc for charged ρ condensation increases monotonically with the temperature. However, including IMC substantially affects the polarized charged ρ condensation around the critical temperature Tc of the chiral phase transition: first, the critical magnetic field e Bc for the charged ρ condensation decreases with the temperature, reaches its minimum value around Tc, and then increases with the temperature. It is quite surprising that the charged ρ can condense above the critical temperature of chiral phase transition with a even smaller critical magnetic field comparing its vacuum value. The Nambu-Jona-Lasinio model calculation shows that in the temperature region of 1 - 1.5 Tc , the critical magnetic field for charged ρ condensation is rather small and in the region of e Bc˜0.15 - 0.3 GeV2 , which suggests that high temperature superconductor might be created through noncentral heavy ion collisions at LHC energies.

Chiral separation and twin-beam photonics

NASA Astrophysics Data System (ADS)

Bradshaw, David S.; Andrews, David L.

2016-03-01

It is well-known that, in a homogeneous fluid medium, most optical means that afford discrimination between molecules of opposite handedness are intrinsically weak effects. The reason is simple: the wide variety of origins for differential response commonly feature real or virtual electronic transitions that break a parity condition. Despite being electric dipole allowed, they manifest the chirality of the material in which they occur by breaking a selection rule that would otherwise preclude the simultaneous involvement of magnetic dipole or electric quadrupole forms of coupling. Although the latter are typically weaker than electric dipole effects by several orders of magnitude, it is the involvement of these weak forms of interaction that are responsible for chiral sensitivity. There have been a number of attempts to cleverly exploit novel optical configurations to enhance the relative magnitude - and hence potentially the efficiency - of chiral discrimination. The prospect of success in any such venture is enticing, because of the huge impact that such an advance might be expected to have in the health, food and medical sectors. Some of these proposals have utilized mirror reflection, and others surface plasmon coupling, or optical binding methods. Several recent works in the literature have drawn attention to a further possibility: the deployment of optical beam interference as a means to achieve chiral separations of sizeable extent. In this paper the underlying theory is fully developed to identify the true scope and limitations of such an approach.

Influence of chirality on catalytic generation of nitric oxide and platelet behavior on selenocystine immobilized TiO2 films.

PubMed

Fan, Yonghong; Pan, Xiaxin; Wang, Ke; Wu, Sisi; Han, Honghong; Yang, Ping; Luo, Rifang; Wang, Hong; Huang, Nan; Tan, Wei; Weng, Yajun

2016-09-01

As nitric oxide (NO) plays vital roles in the cardiovascular system, incorporating this molecule into cardiovascular stents is considered as an effective method. In the present study, selenocystine with different chirality (i.e., l- and d-selenocystine) was used as the catalytic molecule immobilized on TiO2 films for decomposing endogenous NO donor. The influences of surface chirality on NO release and platelet behavior were evaluated. Results show that although the amount of immobilized l-selenocystine on the surface was nearly the same as that of immobilized d-selenocystine, in vitro catalytic NO release tests showed that l-selenocystine immobilized surfaces were more capable of catalyzing the decomposition of S-nitrosoglutathione and thus generating more NO. Accordingly, l-selenocystine immobilized surfaces demonstrated significantly increased inhibiting effects on the platelet adhesion and activation, when compared to d-selenocystine immobilized ones. Measurement of the cGMP concentration of platelets further confirmed that surface chirality played an important role in regulating NO generation and platelet behaviors. Additionally, using bovine serum albumin and fibrinogen as model proteins, the protein adsorption determined with quartz crystal microbalance showed that the l-selenocystine immobilized surface enhanced protein adsorption. In conclusion, surface chirality significantly influences protein adsorption and NO release, which may have significant implications in the design of NO-generating cardiovascular stents. Copyright © 2016 Elsevier B.V. All rights reserved.

The isospin strange asymmetry from the chiral effective theory

NASA Astrophysics Data System (ADS)

Trevisan, Luis Augusto; Mirez, Carlos

2018-05-01

The proposal of the present work is to study the difference between the strange quark-antiquark amount in the proton and neutron. For this purpose, the possible nucleon-hyperon-kaon fluctuations are analyzed with the effective chiral theory. The small difference of particle masses is shown to be in the origin of this isospin asymmetry. The dependence of the results on the mass cutoff parameter and with the coupling constants is analyzed.

Thermally driven spin-Seebeck transport in chiral dsDNA-based molecular devices

NASA Astrophysics Data System (ADS)

Nian, L. L.; Zhang, Rong; Tang, F. R.; Tang, Jun; Bai, Long

2018-03-01

By employing the nonequilibrium Green's function technique, we study the thermal-induced spin-Seebeck transport through a chiral double-stranded DNA (dsDNA) connected to a normal-metal and a ferromagnetic lead. How the main parameters of the dsDNA-based system influence the spin-Seebeck transport is analyzed at length, and the thermally created charge (spin-related) current displays the rectification effect and the negative differential thermal conductance feature. More importantly, the spin current exhibits the rectification behavior of the spin-Seebeck effect; even the perfect spin-Seebeck effect can be obtained with the null charge current. Thus, the chiral dsDNA-based system can act as a spin(charge)-Seebeck diode, spin(charge)-Seebeck switch, and spin(charge)-Seebeck transistor. Our results provide new ways to design spin caloritronic devices based on dsDNA or other organic molecules.

Magnetic fields in turbulent quark matter and magnetar bursts

NASA Astrophysics Data System (ADS)

Dvornikov, Maxim

We analyze the magnetic field evolution in dense quark matter with unbroken chiral symmetry, which can be found inside quark and hybrid stars. The magnetic field evolves owing to the chiral magnetic effect in the presence of the electroweak interaction between quarks. In our study, we also take into account the magnetohydrodynamic turbulence effects in dense quark matter. We derive the kinetic equations for the spectra of the magnetic helicity density and the magnetic energy density as well as for the chiral imbalances. On the basis of the numerical solution of these equations, we find that turbulence effects are important for the behavior of small scale magnetic fields. It is revealed that, under certain initial conditions, these magnetic fields behave similarly to the electromagnetic flashes of some magnetars. We suggest that fluctuations of magnetic fields, described in frames of our model, which are created in the central regions of a magnetized compact star, can initiate magnetar bursts.

Can a Non-Chiral Object Be Made of Two Identical Chiral Moieties?

ERIC Educational Resources Information Center

LeMarechal, Jean Francois

2008-01-01

Several pedagogical objects can be used to discuss chirality. Here, we use the cut of an apple to show that the association of identical chiral moieties can form a non-chiral object. Octahedral chirality is used to find situations equivalent to the cut of the apple. (Contains 5 figures.)

A dispersive treatment of decays

NASA Astrophysics Data System (ADS)

Stoffer, Peter; Colangelo, Gilberto; Passemar, Emilie

2017-01-01

decays have several features of interest: they allow an accurate measurement of ππ-scattering lengths; the decay is the best source for the determination of some low-energy constants of chiral perturbation theory (χPT) one form factor of the decay is connected to the chiral anomaly. We present the results of our dispersive analysis of decays, which provides a resummation of ππ- and Kπ-rescattering effects. The free parameters of the dispersion relation are fitted to the data of the high-statistics experiments E865 and NA48/2. By matching to χPT at NLO and NNLO, we determine the low-energy constants and . In contrast to a pure chiral treatment, the dispersion relation describes the observed curvature of one of the form factors, which we understand as an effect of rescattering beyond NNLO.

Chiral anomalies and effective vector meson Lagrangian beyond the tree level

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dominguez, C.A.

1987-12-01

The decays ..pi../sup O/ ..-->.. ..gamma gamma.., rho ..-->.. ..pi gamma.., ..omega.. ..-->.. ..pi gamma.., ..omega.. ..-->.. 3..pi.. and ..gamma.. ..-->.. 3..pi.. are studied in the framework of the chiral invariant effective Vector Meson Lagrangian beyond the tree level. The standard Lagrangian is enlarged by including an infinite number of radial excitations which are summed according to the dual model. As a result tree level diagrams are modified by a universal form factor at each vertex containing off-mass-shell mesons, but still respecting chiral anomaly low energy theorems. These vertex corrections bring the tree level predictions into better agreement with experiment.more » The presence of the ..omega.. ..-->.. 3..pi.. contact term is confirmed but its strength is considerably smaller than at tree level.« less

Selection of Amino Acid Chirality via Neutrino Interactions with 14N in Crossed Electric and Magnetic Fields

PubMed Central

Boyd, Richard N.; Kajino, Toshitaka; Onaka, Takashi

2018-01-01

Abstract Previous work has suggested that the chirality of the amino acids could be established in the magnetic field of a nascent neutron star from a core-collapse supernova or massive collapsar. The magnetic field would orient the 14N nuclei, and the alignment of its nuclear spin with respect to those of the electron antineutrinos emitted from the collapsing star would determine the probability of destruction of the 14N nuclei by interactions with the antineutrinos. Subsequent work estimated the bulk polarization of the 14N nuclei in large rotating meteoroids in such an environment. The present work adds a crucial piece of this model by describing the details by which the selective 14N nuclear destruction would produce molecular chiral selectivity. The effects of the neutrino-induced interactions on the 14N nuclei bound in amino acids polarized in strong magnetic fields are studied. It is shown that electric fields in the reference frame of the nuclei modify the magnetic field at the nucleus, creating nuclear magnetizations that are asymmetric in chirality. The antineutrino cross sections depend on this magnetization, creating a selective destructive effect. The environmental conditions and sites in which such a selection mechanism could occur are discussed. Selective destruction of D-enantiomers results in enantiomeric excesses which may be sufficient to drive subsequent autocatalysis necessary to produce the few-percent enantiomeric excesses found in meteorites and subsequent homochirality. Molecular quantum chemical calculations were performed for alanine, and the chirality-dependent effects studied were included. A preference for left-handed molecules was found, and enantiomeric excesses as high as 0.02% were estimated for molecules in the electromagnetic conditions expected from a core-collapse supernova. Key Words: Amino acids—Supernovae—Antineutrinos—Enantiomeric excess—Chirality. Astrobiology 18, 190–206. PMID:29160728

On the search for the chiral anomaly in Weyl semimetals: the negative longitudinal magnetoresistance

NASA Astrophysics Data System (ADS)

dos Reis, R. D.; Ajeesh, M. O.; Kumar, N.; Arnold, F.; Shekhar, C.; Naumann, M.; Schmidt, M.; Nicklas, M.; Hassinger, E.

2016-08-01

Recently, the existence of massless chiral (Weyl) fermions has been postulated in a class of semi-metals with a non-trivial energy dispersion. These materials are now commonly dubbed Weyl semi-metals (WSM). One predicted property of Weyl fermions is the chiral or Adler-Bell-Jackiw anomaly, a chirality imbalance in the presence of parallel magnetic and electric fields. In WSM, it is expected to induce a negative longitudinal magnetoresistance (MR). Here, we present experimental evidence that the observation of the chiral anomaly can be hindered by an effect called ‘current jetting’. This effect also leads to a strong apparent negative longitudinal MR, but it is characterized by a highly non-uniform current distribution inside the sample. It appears in materials possessing a large field-induced anisotropy of the resistivity tensor, such as almost compensated high-mobility semimetals due to the orbital effect. In case of a non-homogeneous current injection, the potential distribution is strongly distorted in the sample. As a consequence, an experimentally measured potential difference is not proportional to the intrinsic resistance. Our results on the MR of the Weyl semimetal candidate materials NbP, NbAs, TaAs, and TaP exhibit distinct signatures of an inhomogeneous current distribution, such as a field-induced ‘zero resistance’ and a strong dependence of the ‘measured resistance’ on the position, shape, and type of the voltage and current contacts on the sample. A misalignment between the current and the magnetic-field directions can even induce a ‘negative resistance’. Finite-element simulations of the potential distribution inside the sample, using typical resistance anisotropies, are in good agreement with the experimental findings. Our study demonstrates that great care must be taken before interpreting measurements of a negative longitudinal MR as evidence for the chiral anomaly in putative Weyl semimetals.

Meta-Chirality: Fundamentals, Construction and Applications

PubMed Central

Ma, Xiaoliang; Pu, Mingbo; Li, Xiong; Guo, Yinghui; Gao, Ping; Luo, Xiangang

2017-01-01

Chiral metamaterials represent a special type of artificial structures that cannot be superposed to their mirror images. Due to the lack of mirror symmetry, cross-coupling between electric and magnetic fields exist in chiral mediums and present unique electromagnetic characters of circular dichroism and optical activity, which provide a new opportunity to tune polarization and realize negative refractive index. Chiral metamaterials have attracted great attentions in recent years and have given rise to a series of applications in polarization manipulation, imaging, chemical and biological detection, and nonlinear optics. Here we review the fundamental theory of chiral media and analyze the construction principles of some typical chiral metamaterials. Then, the progress in extrinsic chiral metamaterials, absorbing chiral metamaterials, and reconfigurable chiral metamaterials are summarized. In the last section, future trends in chiral metamaterials and application in nonlinear optics are introduced. PMID:28513560

Chiral acidic amino acids induce chiral hierarchical structure in calcium carbonate

PubMed Central

Jiang, Wenge; Pacella, Michael S.; Athanasiadou, Dimitra; Nelea, Valentin; Vali, Hojatollah; Hazen, Robert M.; Gray, Jeffrey J.; McKee, Marc D.

2017-01-01

Chirality is ubiquitous in biology, including in biomineralization, where it is found in many hardened structures of invertebrate marine and terrestrial organisms (for example, spiralling gastropod shells). Here we show that chiral, hierarchically organized architectures for calcium carbonate (vaterite) can be controlled simply by adding chiral acidic amino acids (Asp and Glu). Chiral, vaterite toroidal suprastructure having a ‘right-handed' (counterclockwise) spiralling morphology is induced by L-enantiomers of Asp and Glu, whereas ‘left-handed' (clockwise) morphology is induced by D-enantiomers, and sequentially switching between amino-acid enantiomers causes a switch in chirality. Nanoparticle tilting after binding of chiral amino acids is proposed as a chiral growth mechanism, where a ‘mother' subunit nanoparticle spawns a slightly tilted, consequential ‘daughter' nanoparticle, which by amplification over various length scales creates oriented mineral platelets and chiral vaterite suprastructures. These findings suggest a molecular mechanism for how biomineralization-related enantiomers might exert hierarchical control to form extended chiral suprastructures. PMID:28406143

Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs

PubMed Central

Jacques, Vincent; Czarnik, Anthony W.; Judge, Thomas M.; Van der Ploeg, Lex H. T.; DeWitt, Sheila H.

2015-01-01

Therapeutics developed and sold as racemates can exhibit a limited therapeutic index because of side effects resulting from the undesired enantiomer (distomer) and/or its metabolites, which at times, forces researchers to abandon valuable scaffolds. Therefore, most chiral drugs are developed as single enantiomers. Unfortunately, the development of some chirally pure drug molecules is hampered by rapid in vivo racemization. The class of compounds known as immunomodulatory drugs derived from thalidomide is developed and sold as racemates because of racemization at the chiral center of the 3-aminoglutarimide moiety. Herein, we show that replacement of the exchangeable hydrogen at the chiral center with deuterium allows the stabilization and testing of individual enantiomers for two thalidomide analogs, including CC-122, a compound currently in human clinical trials for hematological cancers and solid tumors. Using “deuterium-enabled chiral switching” (DECS), in vitro antiinflammatory differences of up to 20-fold are observed between the deuterium-stabilized enantiomers. In vivo, the exposure is dramatically increased for each enantiomer while they retain similar pharmacokinetics. Furthermore, the single deuterated enantiomers related to CC-122 exhibit profoundly different in vivo responses in an NCI-H929 myeloma xenograft model. The (−)-deuterated enantiomer is antitumorigenic, whereas the (+)-deuterated enantiomer has little to no effect on tumor growth. The ability to stabilize and differentiate enantiomers by DECS opens up a vast window of opportunity to characterize the class effects of thalidomide analogs and improve on the therapeutic promise of other racemic compounds, including the development of safer therapeutics and the discovery of new mechanisms and clinical applications for existing therapeutics. PMID:25775521

Cell Chirality Drives Left-Right Asymmetric Morphogenesis.

PubMed

Inaki, Mikiko; Sasamura, Takeshi; Matsuno, Kenji

2018-01-01

Most macromolecules found in cells are chiral, meaning that they cannot be superimposed onto their mirror image. However, cells themselves can also be chiral, a subject that has received little attention until very recently. In our studies on the mechanisms of left-right (LR) asymmetric development in Drosophila , we discovered that cells can have an intrinsic chirality to their structure, and that this "cell chirality" is generally responsible for the LR asymmetric development of certain organs in this species. The actin cytoskeleton plays important roles in the formation of cell chirality. In addition, Myosin31DF ( Myo31DF ), which encodes Drosophila Myosin ID, was identified as a molecular switch for cell chirality. In other invertebrate species, including snails and Caenorhabditis elegans , chirality of the blastomeres, another type of cell chirality, determines the LR asymmetry of structures in the body. Thus, chirality at the cellular level may broadly contribute to LR asymmetric development in various invertebrate species. Recently, cell chirality was also reported for various vertebrate cultured cells, and studies suggested that cell chirality is evolutionarily conserved, including the essential role of the actin cytoskeleton. Although the biological roles of cell chirality in vertebrates remain unknown, it may control LR asymmetric development or other morphogenetic events. The investigation of cell chirality has just begun, and this new field should provide valuable new insights in biology and medicine.

Cell chirality: its origin and roles in left–right asymmetric development

PubMed Central

Inaki, Mikiko; Liu, Jingyang

2016-01-01

An item is chiral if it cannot be superimposed on its mirror image. Most biological molecules are chiral. The homochirality of amino acids ensures that proteins are chiral, which is essential for their functions. Chirality also occurs at the whole-cell level, which was first studied mostly in ciliates, single-celled protozoans. Ciliates show chirality in their cortical structures, which is not determined by genetics, but by ‘cortical inheritance’. These studies suggested that molecular chirality directs whole-cell chirality. Intriguingly, chirality in cellular structures and functions is also found in metazoans. In Drosophila, intrinsic cell chirality is observed in various left–right (LR) asymmetric tissues, and appears to be responsible for their LR asymmetric morphogenesis. In other invertebrates, such as snails and Caenorhabditis elegans, blastomere chirality is responsible for subsequent LR asymmetric development. Various cultured cells of vertebrates also show intrinsic chirality in their cellular behaviours and intracellular structural dynamics. Thus, cell chirality may be a general property of eukaryotic cells. In Drosophila, cell chirality drives the LR asymmetric development of individual organs, without establishing the LR axis of the whole embryo. Considering that organ-intrinsic LR asymmetry is also reported in vertebrates, this mechanism may contribute to LR asymmetric development across phyla. This article is part of the themed issue ‘Provocative questions in left–right asymmetry’. PMID:27821533

Cell chirality: its origin and roles in left-right asymmetric development.

PubMed

Inaki, Mikiko; Liu, Jingyang; Matsuno, Kenji

2016-12-19

An item is chiral if it cannot be superimposed on its mirror image. Most biological molecules are chiral. The homochirality of amino acids ensures that proteins are chiral, which is essential for their functions. Chirality also occurs at the whole-cell level, which was first studied mostly in ciliates, single-celled protozoans. Ciliates show chirality in their cortical structures, which is not determined by genetics, but by 'cortical inheritance'. These studies suggested that molecular chirality directs whole-cell chirality. Intriguingly, chirality in cellular structures and functions is also found in metazoans. In Drosophila, intrinsic cell chirality is observed in various left-right (LR) asymmetric tissues, and appears to be responsible for their LR asymmetric morphogenesis. In other invertebrates, such as snails and Caenorhabditis elegans, blastomere chirality is responsible for subsequent LR asymmetric development. Various cultured cells of vertebrates also show intrinsic chirality in their cellular behaviours and intracellular structural dynamics. Thus, cell chirality may be a general property of eukaryotic cells. In Drosophila, cell chirality drives the LR asymmetric development of individual organs, without establishing the LR axis of the whole embryo. Considering that organ-intrinsic LR asymmetry is also reported in vertebrates, this mechanism may contribute to LR asymmetric development across phyla.This article is part of the themed issue 'Provocative questions in left-right asymmetry'. © 2016 The Authors.

EFFECT OF PREGNANCY ON THE DISPOSITION OF 2,2′,3,5′,6-PENTACHLOROBIPHENYL (PCB 95) ATROPISOMERS AND THEIR HYDROXYLATED METABOLITES IN FEMALE MICE

PubMed Central

Kania-Korwel, Izabela; Barnhart, Christopher D.; Lein, Pamela J.; Lehmler, Hans-Joachim

2015-01-01

Chiral PCBs, such as PCB 95, are developmental neurotoxicants that undergo atropisomeric enrichment in non-pregnant, adult mice. Because pregnancy is associated with changes in hepatic cytochrome P450 enzyme activity as well as lipid disposition and metabolism, this study investigates the effect of pregnancy on the maternal disposition of chiral PCBs. Female C57Bl/6 mice (8 weeks old) were dosed daily beginning 2 weeks prior to conception and continuing throughout gestation and lactation (56 days total) with racemic PCB 95 (0, 0.1, 1.0 or 6.0 mg/kg body wt/day) in peanut butter. Levels and chiral signatures of PCB 95 and its hydroxylated metabolites (OH-PCBs) were determined in adipose, blood, brain and liver. Tissue levels of PCB 95 increased 4 to 12 fold with increasing dose, with considerable enrichment of the second eluting atropisomer in all tissues (EF range 0.11 to 0.26). OH-PCBs displayed atropisomeric enrichment in blood and liver, but were not detected in adipose and brain. Levels of PCB 95 and its metabolites were 2 to 11 fold lower in pregnant dams relative to those previously reported in non-pregnant age-matched female mice; however, PCB 95 and OH-PCB profiles and chiral signatures were similar between both studies. In contrast, human brain samples contained racemic PCB 95 residues (EF=0.50). These results demonstrate that changes in cytochrome P450 enzyme activity and lipid disposition during pregnancy reduce the PCB body burden in dams, but do not affect metabolite profiles or chiral signatures. The differences in chiral signatures between mice and humans suggest species-specific differences in atropisomeric disposition, the toxicological significance of which remain to be determined. PMID:26271003

Effect of pregnancy on the disposition of 2,2',3,5',6-pentachlorobiphenyl (PCB 95) atropisomers and their hydroxylated metabolites in female mice.

PubMed

Kania-Korwel, Izabela; Barnhart, Christopher D; Lein, Pamela J; Lehmler, Hans-Joachim

2015-09-21

Chiral PCBs, such as PCB 95, are developmental neurotoxicants that undergo atropisomeric enrichment in nonpregnant adult mice. Because pregnancy is associated with changes in hepatic cytochrome P450 enzyme activity as well as lipid disposition and metabolism, this study investigates the effect of pregnancy on the maternal disposition of chiral PCBs. Female C57BL/6 mice (8 weeks old) were dosed daily beginning 2 weeks prior to conception and continuing throughout gestation and lactation (56 days total) with racemic PCB 95 (0, 0.1, 1.0, or 6.0 mg/kg body wt/day) in peanut butter. Levels and chiral signatures of PCB 95 and its hydroxylated metabolites (OH-PCBs) were determined in adipose, blood, brain, and liver. Tissue levels of PCB 95 increased 4- to 12-fold with increasing dose, with considerable enrichment of the second eluting atropisomer in all tissues (EF range 0.11 to 0.26). OH-PCBs displayed atropisomeric enrichment in blood and liver but were not detected in adipose and brain. Levels of PCB 95 and its metabolites were 2- to 11-fold lower in pregnant dams relative to those previously reported in nonpregnant age-matched female mice; however, PCB 95 and OH-PCB profiles and chiral signatures were similar between both studies. In contrast, human brain samples contained racemic PCB 95 residues (EF = 0.50). These results demonstrate that changes in cytochrome P450 enzyme activity and lipid disposition during pregnancy reduce the PCB body burden in dams but do not affect metabolite profiles or chiral signatures. The differences in chiral signatures between mice and humans suggest species-specific differences in atropisomeric disposition, the toxicological significance of which remains to be determined.

Light-front representation of chiral dynamics with Δ isobar and large-N c relations

DOE PAGES

Granados, C.; Weiss, C.

2016-06-13

Transverse densities describe the spatial distribution of electromagnetic current in the nucleon at fixed light-front time. At peripheral distances b = O(M π –1) the densities are governed by chiral dynamics and can be calculated model-independently using chiral effective field theory (EFT). Recent work has shown that the EFT results can be represented in first-quantized form, as overlap integrals of chiral light-front wave functions describing the transition of the nucleon to soft-pion-nucleon intermediate states, resulting in a quantum-mechanical picture of the peripheral transverse densities. We now extend this representation to include intermediate states with Δ isobars and implement relations basedmore » on the large-N c limit of QCD. We derive the wave function overlap formulas for the Δ contributions to the peripheral transverse densities by way of a three-dimensional reduction of relativistic chiral EFT expressions. Our procedure effectively maintains rotational invariance and avoids the ambiguities with higher-spin particles in the light-front time-ordered approach. We study the interplay of πN and πΔ intermediate states in the quantum-mechanical picture of the densities in a transversely polarized nucleon. We show that the correct N c-scaling of the charge and magnetization densities emerges as the result of the particular combination of currents generated by intermediate states with degenerate N and Δ. The off-shell behavior of the chiral EFT is summarized in contact terms and can be studied easily. As a result, the methods developed here can be applied to other peripheral densities and to moments of the nucleon's generalized parton distributions.« less

Chiral Dynamics 2006

NASA Astrophysics Data System (ADS)

Ahmed, Mohammad W.; Gao, Haiyan; Weller, Henry R.; Holstein, Barry

2007-10-01

pt. A. Plenary session. Opening remarks: experimental tests of chiral symmetry breaking / A. M. Bernstein. [Double pie symbols] scattering / H. Leutwyler. Chiral effective field theory in a [Triangle]-resonance region / V. Pascalutsa. Some recent developments in chiral perturbation theory / Ulf-G. Mei ner. Chiral extrapolation and nucleon structure from the lattice / R.D. Young. Recent results from HAPPEX / R. Michaels. Chiral symmetries and low energy searches for new physics / M.J. Ramsey-Musolf. Kaon physics: recent experimental progress / M. Moulson. Status of the Cabibbo angle / V. Cirigliano. Lattice QCD and nucleon spin structure / J.W. Negele. Spin sum rules and polarizabilities: results from Jefferson lab / J-P Chen. Compton scattering and nucleon polarisabilities / Judith A. McGovern. Virtual compton scattering at MIT-bates / R. Miskimen. Physics results from the BLAST detector at the BATES accelerator / R.P. Redwine. The [Pie sympbol]NN system, recent progress / C. Hanhart. Application of chiral nuclear forces to light nuclei / A. Nogga. New results on few-body experiments at low energy / Y. Nagai. Few-body lattice calculations / M.J. Savage. Research opportunities at the upgraded HI?S facility / H.R. Weller -- pt. B. Goldstone boson dynamics. Working group summary: Goldstone Boson dynamics / G. Colangelo and S. Giovannella. Recent results on radiative Kaon decays from NA48 and NA48/2 / S.G. López. Cusps in K-->3 [Pie symbol] decays / B. Kubis. Recent KTeV results on radiative Kaon decays / M.C. Ronquest. The [Double pie symbols] scattering amplitude / J.R. Peláez. Determination of the Regge parameters in the [Double pie symbols] scattering amplitude / I. Caprini. e+e- Hadronic cross section measurement at DA[symbol]NE with the KLOE detector / P. Beltrame. Measurement of the form factors of e+e- -->2([Pie symbol]+[Pie symbol]-), pp and the resonant parameters of the heavy charmonia at BES / H. Hu. Measurement of e+e- multihadronic cross section below 4.5 GeV with BABAR / A. Denig. The pion vector form-factor and (g-2)u / C. Smith. Partially quenched CHPT results to two loops / J. Bijnens. Pion-pion scattering with mixed action lattice QCD / P.F. Bedaque. Meson systems with Ginsparg-Wilson valence quarks / A. Walker-Loud. Low energy constants from the MILC collaboration / C. Bernard. Finite volume effects: lattice meets CHPT / G. Schierholz. Lattice QCD simulations with two light dynamical (Wilson) quarks / L. Giusti. Do we understand the low-energy constant L8? / M. Golterman. Quark mass dependence of LECs in the two-flavour sector / M. Schmid. Progress report on the [Pie symbol]0 Lifetime experiment (PRIMEX) at Jlab / D.E. McNulty. Determination of the charged pion polarizabilities / L.V. Fil'kov. Proposed measurement of electroproduction of [Pie symbol]0 near threshold using a large acceptance spectrometer / R.A. Lindgren. The [Pie symbol] meson in [Pie symbol]K scattering / B. Moussallam. Strangeness -1 Meson-Baryon scattering S-wave / J.A. Oller. Results on light mesons decays and dynamics at KLOE / M. Martini. Studies of decays of [symbol] and [symbol] mesons with WASA detector / A. Kupsc. Heavy Quark-Diquark symmetry and X PT for doubly heavy baryons / T. Mehen. HHChPT applied to the charmed-strange parity partners/ R.P. Springer. Study of pion structure through precise measurements of the [Pie symbol]+ --> e+[symbol] decay / D. Pocanic. Exceptional and non-exceptional contributions to the radiative [Pie symbol] decay / V. Mateu. Leading chiral logarithms from unitarity, analyticity and the Roy equations / A. Fuhrer. All orders symmetric subtraction of the nonlinear sigma model in D=4 / A. Quadri -- pt. C. Chiral dynamics in few-nucleon systems. Working group summary: chiral dynamics in few-nucleon systems / H.W Hammer, N. Kalantar-Nayestanaki, and D.R. Phillips. Power counting in nuclear chiral effective field theory / U. van Kolck. On the consistency of Weinberg's power counting / U-G Mei ner. Renormalization of singular potentials and power counting / M.P. Valderrrama. The challenge of calculating Baryon-Baryon scattering from lattice QCD / S.R. Beane. Precise absolute np scattering cross section and the charged [Pie symbol] NN coupling constant / S. E. Vigdor. Probing hadronic parity violation using few nucleon systems / S.A. Page. Extracting the neutron-neutron scattering length from neutron-deuteron breakup / C.R. Howell. Extraction of [equationl] from [Pie symbol]-d --> [equation] / A. Grudestig. The three- and four-body system with large scattering length / L. Platter. 3N and 4N systems and the Ay puzzle / T. Clegg. Recent progress in nuclear lattice simulations with effective field theory / D. Lee. Few-body studies at KVI / J.G. Messchendorp. Results of three nucleon experiments from RIKEN / K. Sekiguchi. A new opportunity to measure the total photoabsorption cross section of helium / P. T. Debevec. Three-body photodisintegration of 3He with double polarizations / X. Zong. Large two-pion exchange contributions to the pp --> pp[Pie symbol]0 reaction / F. Myhrer. Towards a systematic theory of nuclear forces / E. Epelbaum. Ab initio calculations of eletromagnetic reactions in light nuclei / W. Leidemann. Electron scattering from a polarized deuterium target at BLAST / R. Fatemi. Neutron-neutron scattering length from the reaction [equation] / V. Lensky. Renormalization group analysis of nuclear current operators / S.X. Nakamura. Recent results and future plans at MAX-LAB / K.G. Fissum. Nucleon polarizabilities from deutron compton scattering, and its lessons for chiral power counting / H. W. Grie hammer. Compton scattering on HE-3 / D. Choudhury -- pt. D. Hadron structure and Meson-Baryon interactions. Summary of the working group on Hadron structure and Meson-Baryon interactions / G. Feldman and T.R. Hemmert. Finite volume effects: lattice meets CHPT / G. Schierholz. Lattice discretization errors in chiral effective field theories / B.C. Tiburzi. SU(3)-breaking effects in hyperon semileptonic decays from lattice QCD / S. Simula. Uncertainty bands for chiral extrapolations / B.U. Musch. Update of the nucleon electromagnetic form factors / C. B. Crawford. N and N to ? transition from factors from lattice QCD / C. Alexandrou. The [equation] transition at low Q2 and the pionic contribution / S. Stave. Strange Quark CoNtributions to the form factors of the nucleon / F. Benmokhtar. Dynamical polarizabilities of the nucleon / B. Pasquini. Hadron magnetic moments and polarizabilities in lattice QCD / F.X. Lee. Spin-dependent compton scattering from 3He and the neutron spin polarizabilities / H. Gao. Chiral dynamics from Dyson-Schwinger equations / C.D. Roberts. Radiative neutron [Beta symbol]-decay in effective field theory / S. Gardner. Comparison between different renormalization schemes for co-variant BChPT / T.A. Gail. Non-perturbative study of the light pseudoscalar masses in chiral dynamics / José Antonio Oller. Masses and widths of hadrons in nuclear matter / M. Kotulla. Chiral effective field theory at finite density / R.J. Furnstahl. The K-nuclear interaction: a search fro deeply bound K-nuclear clusters / P. Camerini. Moments of GPDs from lattice QCD / D.G. Richards. Generalized parton distributions in effective field theory / J.W. Chen. Near-threshold pion production: experimental update / M.W. Ahmed. Pion photoproduction near threshold theory update / L. Tiator.

Selectively transporting small chiral particles with circularly polarized Airy beams.

PubMed

Lu, Wanli; Chen, Huajin; Guo, Sandong; Liu, Shiyang; Lin, Zhifang

2018-05-01

Based on the full wave simulation, we demonstrate that a circularly polarized vector Airy beam can selectively transport small chiral particles along a curved trajectory via the chirality-tailored optical forces. The transverse optical forces can draw the chiral particles with different particle chirality towards or away from the intensity maxima of the beam, leading to the selective trapping in the transverse plane. The transversely trapped chiral particles are then accelerated along a curved trajectory of the Airy beam by the chirality-tailored longitudinal scattering force, rendering an alternative way to sort and/or transport chiral particles with specified helicity. Finally, the underlying physics of the chirality induced transverse trap and de-trap phenomena are examined by the analytical theory within the dipole approximation.

Silver Films with Hierarchical Chirality.

PubMed

Ma, Liguo; Cao, Yuanyuan; Duan, Yingying; Han, Lu; Che, Shunai

2017-07-17

Physical fabrication of chiral metallic films usually results in singular or large-sized chirality, restricting the optical asymmetric responses to long electromagnetic wavelengths. The chiral molecule-induced formation of silver films prepared chemically on a copper substrate through a redox reaction is presented. Three levels of chirality were identified: primary twisted nanoflakes with atomic crystal lattices, secondary helical stacking of these nanoflakes to form nanoplates, and tertiary micrometer-sized circinates consisting of chiral arranged nanoplates. The chiral Ag films exhibited multiple plasmonic absorption- and scattering-based optical activities at UV/Vis wavelengths based on their hierarchical chirality. The Ag films showed chiral selectivity for amino acids in catalytic electrochemical reactions, which originated from their primary atomic crystal lattices. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Switching chiral solitons for algebraic operation of topological quaternary digits

NASA Astrophysics Data System (ADS)

Kim, Tae-Hwan; Cheon, Sangmo; Yeom, Han Woong

2017-02-01

Chiral objects can be found throughout nature; in condensed matter chiral objects are often excited states protected by a system's topology. The use of chiral topological excitations to carry information has been demonstrated, where the information is robust against external perturbations. For instance, reading, writing, and transfer of binary information have been demonstrated with chiral topological excitations in magnetic systems, skyrmions, for spintronic devices. The next step is logic or algebraic operations of such topological bits. Here, we show experimentally the switching between chiral topological excitations or chiral solitons of different chirality in a one-dimensional electronic system with Z4 topological symmetry. We found that a fast-moving achiral soliton merges with chiral solitons to switch their handedness. This can lead to the realization of algebraic operation of Z4 topological charges. Chiral solitons could be a platform for storage and operation of robust topological multi-digit information.

Chirality-controlled crystallization via screw dislocations.

PubMed

Sung, Baeckkyoung; de la Cotte, Alexis; Grelet, Eric

2018-04-11

Chirality plays an important role in science from enantiomeric separation in chemistry to chiral plasmonics in nanotechnology. However, the understanding of chirality amplification from chiral building blocks to ordered helical superstructures remains a challenge. Here, we demonstrate that topological defects, such as screw dislocations, can drive the chirality transfer from particle to supramolecular structure level during the crystallization process. By using a model system of chiral particles, which enables direct imaging of single particle incorporation into growing crystals, we show that the crystallization kinetic pathway is the key parameter for monitoring, via the defects, the chirality amplification of the crystalline structures from racemic to predominantly homohelical. We provide an explanation based on the interplay between geometrical frustration, racemization induced by thermal fluctuations, and particle chirality. Our results demonstrate that screw dislocations not only promote the growth, but also control the chiral morphology and therefore the functionality of crystalline states.

Influence of Chirality in Ordered Block Copolymer Phases

NASA Astrophysics Data System (ADS)

Prasad, Ishan; Grason, Gregory

2015-03-01

Block copolymers are known to assemble into rich spectrum of ordered phases, with many complex phases driven by asymmetry in copolymer architecture. Despite decades of study, the influence of intrinsic chirality on equilibrium mesophase assembly of block copolymers is not well understood and largely unexplored. Self-consistent field theory has played a major role in prediction of physical properties of polymeric systems. Only recently, a polar orientational self-consistent field (oSCF) approach was adopted to model chiral BCP having a thermodynamic preference for cholesteric ordering in chiral segments. We implement oSCF theory for chiral nematic copolymers, where segment orientations are characterized by quadrupolar chiral interactions, and focus our study on the thermodynamic stability of bi-continuous network morphologies, and the transfer of molecular chirality to mesoscale chirality of networks. Unique photonic properties observed in butterfly wings have been attributed to presence of chiral single-gyroid networks, this has made it an attractive target for chiral metamaterial design.

Chiral permselectivity in surface-modified nanoporous opal films.

PubMed

Cichelli, Julie; Zharov, Ilya

2006-06-28

Nanoporous 7 mum thin opal films comprising 35 layers of 200 nm diameter SiO2 spheres were assembled on Pt electrodes and modified with chiral selector moieties on the silica surface. Diffusion of chiral redox species through the opals was studied by cyclic voltammetry. The chiral opal films demonstrate high selectivity for transport of one enantiomer over the other. This chiral permselectivity is attributed to the surface-facilitated transport utilizing noncovalent interactions between the chiral permeant molecules and surface-bound chiral selectors.

Chiral bobbers and skyrmions in epitaxial FeGe/Si(111) films

NASA Astrophysics Data System (ADS)

Ahmed, Adam S.; Rowland, James; Esser, Bryan D.; Dunsiger, Sarah R.; McComb, David W.; Randeria, Mohit; Kawakami, Roland K.

2018-04-01

We report experimental and theoretical evidence for the formation of chiral bobbers—an interfacial topological spin texture—in FeGe films grown by molecular beam epitaxy. After establishing the presence of skyrmions in FeGe/Si(111) thin-film samples through Lorentz transmission electron microscopy and the topological Hall effect, we perform magnetization measurements that reveal an inverse relationship between the film thickness and the slope of the susceptibility (d χ /d H ). We present evidence for the evolution as a function of film thickness L from a skyrmion phase for L LD/2 , where LD˜70 nm is the FeGe pitch length. We show using micromagnetic simulations that chiral bobbers, earlier predicted to be metastable, are in fact the stable ground state in the presence of an additional interfacial Rashba Dzyaloshinskii-Moriya interaction.

Nonlinear chiral plasma transport in rotating coordinates

NASA Astrophysics Data System (ADS)

Dayi, Ömer F.; Kilinçarslan, Eda

2017-08-01

The nonlinear transport features of inhomogeneous chiral plasma in the presence of electromagnetic fields, in rotating coordinates are studied within the relaxation time approach. The chiral distribution functions up to second order in the electric field in rotating coordinates and the derivatives of chemical potentials are established by solving the Boltzmann transport equation. First, the vector and axial current densities in the weakly ionized chiral plasma for vanishing magnetic field are calculated. They involve the rotational analogues of the Hall effect as well as several new terms arising from the Coriolis and fictitious centrifugal forces. Then in the short relaxation time regime the angular velocity and electromagnetic fields are treated as perturbations. The current densities are obtained by retaining the terms up to second order in perturbations. The time evolution equations of the inhomogeneous chemical potentials are derived by demanding that collisions conserve the particle number densities.

Series of chiral interpenetrating 3d-4f heterometallic MOFs: Luminescent sensors and magnetic properties

NASA Astrophysics Data System (ADS)

Zhang, Xiaolei; Chen, Chen; Liu, Xiaoli; Gao, Peng; Hu, Ming

2017-09-01

Series of chiral 3d-4f heterometallic MOFs based on a multidentate terpyridyl carboxylic acid ligand have been synthesized under the solvothermal conditions, namely, [LnZnL(CO3)2(H2O)]n (Ln = Eu (1), Gd (2), Dy (3), Ho (4), Er (5), Tm (6), Yb (7), Lu (8)) (HL = 4‧-(4-carboxyphenyl)-2,2‧:6‧,2″-terpyridine). Compounds 1-8 were structurally characterized by the elemental analyses, infrared spectra, and single crystal X-ray diffractions. Compounds 1-8 exhibit the chiral interpenetrating 3D frameworks. Interestingly, 1 can serve as the luminescent sensor to detect nitrobenzene molecules with high sensitivity. The investigations on CD spectra of single crystals clearly assigned the Cotton effect, indicating that there exist two chiral enantiomers of 1-8 in the course of crystallization. The magnetic properties of 2 and 7 were exploited, respectively.

Attosecond-resolved photoionization of chiral molecules.

PubMed

Beaulieu, S; Comby, A; Clergerie, A; Caillat, J; Descamps, D; Dudovich, N; Fabre, B; Géneaux, R; Légaré, F; Petit, S; Pons, B; Porat, G; Ruchon, T; Taïeb, R; Blanchet, V; Mairesse, Y

2017-12-08

Chiral light-matter interactions have been investigated for two centuries, leading to the discovery of many chiroptical processes used for discrimination of enantiomers. Whereas most chiroptical effects result from a response of bound electrons, photoionization can produce much stronger chiral signals that manifest as asymmetries in the angular distribution of the photoelectrons along the light-propagation axis. We implemented self-referenced attosecond photoelectron interferometry to measure the temporal profile of the forward and backward electron wave packets emitted upon photoionization of camphor by circularly polarized laser pulses. We measured a delay between electrons ejected forward and backward, which depends on the ejection angle and reaches 24 attoseconds. The asymmetric temporal shape of electron wave packets emitted through an autoionizing state further reveals the chiral character of strongly correlated electronic dynamics. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Pion-photon reactions and chiral dynamics in Primakoff processes at COMPASS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friedrich, Jan Michael

2016-01-22

With the COMPASS experiment at CERN, pion-photon reactions are investigated via the Primakoff effect, implying that high-energetic pions react with the quasi-real photon field surrounding the target nuclei. The production of a single hard photon in such a pion scattering at lowest momentum transfer to the nucleus is related to pion Compton scattering. From the measured cross-section shape, the pion polarisability is determined. The COMPASS measurement is in contradiction to the earlier dedicated measurements, and rather in agreement with the theoretical expectation from chiral perturbation theory. In the same data taking, reactions with neutral and charged pions in the finalmore » state are measured and analyzed. At low energy in the pion-photon centre-of-momentum system, these reactions are governed by chiral dynamics and contain information relevant for chiral perturbation theory. At higher energies, resonances are produced and their radiative coupling is investigated.« less

Predicting the switchable screw sense in fluorene-based polymers.

PubMed

Pietropaolo, Adriana; Wang, Yue; Nakano, Tamaki

2015-02-23

A chirality-switching free-energy landscape was reconstructed on a 43-mer of poly(9,9-dioctylfluoren-2,7-diyl) (PDOF). The simulations were conducted on amorphous silica surface as well as in the vacuum phase for a single chain or for a group of sixteen chains. The achiral-to-chiral transition occurs only on amorphous silica (activation free-energy 35 kcal mol(-1) ), where the enantiomeric (homochiral) basins are detected. This was supported by the experiments where effective chirality induction to PDOF using circularly polarized light (CPL) was attained only for a film deposited on a quartz glass and not for a solution or a suspension. These results indicate that interactions of PDOF with amorphous silica play a crucial role in chirality switching. Importance of chain assembling was also indicated. Theoretical ECD spectra of the enantiomeric basins containing a 51 helix reproduce the experimental spectra. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Chirality-selected phase behaviour in ionic polypeptide complexes

DOE PAGES

Perry, Sarah L.; Leon, Lorraine; Hoffmann, Kyle Q.; ...

2015-01-14

In this study, polyelectrolyte complexes present new opportunities for self-assembled soft matter. Factors determining whether the phase of the complex is solid or liquid remain unclear. Ionic polypeptides enable examination of the effects of stereochemistry on complex formation. Here we demonstrate that chirality determines the state of polyelectrolyte complexes, formed from mixing dilute solutions of oppositely charged polypeptides, via a combination of electrostatic and hydrogen-bonding interactions. Fluid complexes occur when at least one of the polypeptides in the mixture is racemic, which disrupts backbone hydrogen-bonding networks. Pairs of purely chiral polypeptides, of any sense, form compact, fibrillar solids with amore » β-sheet structure. Analogous behaviour occurs in micelles formed from polypeptide block copolymers with polyethylene oxide, where assembly into aggregates with either solid or fluid cores, and eventually into ordered phases at high concentrations, is possible. Chirality is an exploitable tool for manipulating material properties in polyelectrolyte complexation.« less

Orbital angular momentum and spectral flow in two-dimensional chiral superfluids.

PubMed

Tada, Yasuhiro; Nie, Wenxing; Oshikawa, Masaki

2015-05-15

We study the orbital angular momentum (OAM) L_{z} in two-dimensional chiral (p_{x}+ip_{y})^{ν}-wave superfluids (SFs) of N fermions on a disk at zero temperature, in terms of spectral asymmetry and spectral flow. It is shown that L_{z}=νN/2 for any integer ν, in the Bose-Einstein condensation regime. In contrast, in the BCS limit, while the OAM is L_{z}=N/2 for the p+ip-wave SF, for chiral SFs with ν≥2, the OAM is remarkably suppressed as L_{z}=N×O(Δ_{0}/ϵ_{F})≪N, where Δ_{0} is the gap amplitude and ϵ_{F} is the Fermi energy. We demonstrate that the difference between the p+ip-wave SF and the other chiral SFs in the BCS regimes originates from the nature of edge modes and related depairing effects.

Notes on phase transitions and the role of spin fluctuations

NASA Astrophysics Data System (ADS)

Stishov, S. M.

2016-09-01

The physical properties of two chiral systems with localized and delocalized magnetic moments, {\\text{Cu}}2{\\text{OSeO}}3 and MnSi, are reviewed. It is concluded that the longitudinal fluctuations of magnetic moments have no strong effect on the qualitative picture of phase transitions and the magnetic phase diagrams of chiral systems.

Nanoscale chirality in metal and semiconductor nanoparticles

PubMed Central

Thomas, K. George

2016-01-01

The field of chirality has recently seen a rejuvenation due to the observation of chirality in inorganic nanomaterials. The advancements in understanding the origin of nanoscale chirality and the potential applications of chiroptical nanomaterials in the areas of optics, catalysis and biosensing, among others, have opened up new avenues toward new concepts and design of novel materials. In this article, we review the concept of nanoscale chirality in metal nanoclusters and semiconductor quantum dots, then focus on recent experimental and theoretical advances in chiral metal nanoparticles and plasmonic chirality. Selected examples of potential applications and an outlook on the research on chiral nanomaterials are additionally provided. PMID:27752651

Nanoscale chirality in metal and semiconductor nanoparticles.

PubMed

Kumar, Jatish; Thomas, K George; Liz-Marzán, Luis M

2016-10-18

The field of chirality has recently seen a rejuvenation due to the observation of chirality in inorganic nanomaterials. The advancements in understanding the origin of nanoscale chirality and the potential applications of chiroptical nanomaterials in the areas of optics, catalysis and biosensing, among others, have opened up new avenues toward new concepts and design of novel materials. In this article, we review the concept of nanoscale chirality in metal nanoclusters and semiconductor quantum dots, then focus on recent experimental and theoretical advances in chiral metal nanoparticles and plasmonic chirality. Selected examples of potential applications and an outlook on the research on chiral nanomaterials are additionally provided.

A chiroptical switch based on supramolecular chirality transfer through alkyl chain entanglement and dynamic covalent bonding.

PubMed

Lv, Kai; Qin, Long; Wang, Xiufeng; Zhang, Li; Liu, Minghua

2013-12-14

Chirality transfer is an interesting phenomenon in Nature, which represents an important step to understand the evolution of chiral bias and the amplification of the chirality. In this paper, we report the chirality transfer via the entanglement of the alkyl chains between chiral gelator molecules and achiral amphiphilic Schiff base. We have found that although an achiral Schiff base amphiphile could not form organogels in any kind of organic solvents, it formed co-organogels when mixed with a chiral gelator molecule. Interestingly, the chirality of the gelator molecules was transferred to the Schiff base chromophore in the mixed co-gels and there was a maximum mixing ratio for the chirality transfer. Furthermore, the supramolecular chirality was also produced based on a dynamic covalent chemistry of an imine formed by the reaction between an aldehyde and an amine. Such a covalent bond of imine was formed reversibly depending on the pH variation. When the covalent bond was formed the chirality transfer occurred, when it was destroyed, the transfer stopped. Thus, a supramolecular chiroptical switch is obtained based on supramolecular chirality transfer and dynamic covalent chemistry.

Chiral separation and quantitation of cetirizine and hydroxyzine by maltodextrin-mediated CE in human plasma: effect of zwitterionic property of cetirizine on enantioseparation.

PubMed

Nojavan, Saeed; Fakhari, Ali Reza

2011-03-01

In the present study, a very simple CE method for chiral separation and quantitation of zwitterionic cetirizine (CTZ), as the main metabolite of hydroxyzine (HZ), and HZ has been developed. In addition, the effect of zwitterionic property of CTZ on enantioseparation was investigated. Maltodextrin, a linear polysaccharide, as a chiral selector was used and several parameters affecting the separation such as pH of BGE, concentration of chiral selector and applied voltage were studied. The best BGE conditions for CTZ and HZ enantiomers were optimized as 75 mM sodium phosphate solution at pH of 2.0, containing 5% w/v maltodextrin. Results showed that, compared to HZ, pH of BGE was an effective parameter in enantioseparation of CTZ due to the zwitterionic property of CTZ. The linear range of the method was over 30-1200 ng/mL for all enantiomers of CTZ and HZ. The quantification and detection limits (S/N=3) of all enantiomers were 30 and 10 ng/mL, respectively. The method was used to quantitative enantioseparation of CTZ and HZ in spiked human plasma. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Effects of nonequilibrated topological charge distributions on pseudoscalar meson masses and decay constants

NASA Astrophysics Data System (ADS)

Bernard, C.; Toussaint, D.

2018-04-01

We study the effects of failure to equilibrate the squared topological charge Q2 on lattice calculations of pseudoscalar masses and decay constants. The analysis is based on chiral perturbation theory calculations of the dependence of these quantities on the QCD vacuum angle θ . For the light-light partially quenched case, we rederive the known chiral perturbation theory results of Aoki and Fukaya, but using the nonperturbatively valid chiral theory worked out by Golterman, Sharpe and Singleton, and by Sharpe and Shoresh. We then extend these calculations to heavy-light mesons. Results when staggered taste violations are important are also presented. The derived Q2 dependence is compared to that of simulations using the MILC Collaboration's ensembles of lattices with four flavors of dynamical highly improved staggered quarks. We find agreement, albeit with large statistical errors. These results can be used to correct for the leading effects of unequilibrated Q2, or to make estimates of the systematic error coming from the failure to equilibrate Q2. In an appendix, we show that the partially quenched chiral theory may be extended beyond a lower bound on valence masses discovered by Sharpe and Shoresh. Subtleties occurring when a sea-quark mass vanishes are discussed in another appendix.

Chemical synthesis of water-soluble, chiral conducting-polymer complexes

DOEpatents

Wang, Hsing-Lin; McCarthy, Patrick A.; Yang, Sze Cheng

2003-01-01

The template-guided synthesis of water-soluble, chiral conducting polymer complexes is described. Synthesis of water-soluble polyaniline complexes is achieved by carefully controlling the experimental parameters such as; acid concentration, ionic strength, monomer/template ratio, total reagent concentration, and order of reagent addition. Chiral (helical) polyaniline complexes can be synthesized by addition of a chiral inducing agent (chiral acid) prior to polymerization, and the polyaniline helix can be controlled by the addition of the (+) or (-) form of the chiral acid. Moreover the quantity of chiral acid and the salt content has a significant impact on the degree of chirality in the final polymer complexes. The polyaniline and the template have been found to be mixed at the molecular level which results in chiral complexes that are robust through repeated doping and dedoping cycles.