Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-12
... Electronic Funds Transfer (EFT) Payment; and Trace Request Direct Deposit AGENCY: Financial Management... collection. By this notice, the Financial Management Service solicits comments concerning forms FMS-150.1... comments to Financial Management Service, 3700 East West Highway, Records and Information Management Branch...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-20
... regarding trace organics and environmental monitoring; statistics, particularly regarding experimental design of field studies; human health effects and risk assessment; civil and environmental engineering...
Factors leading to the involvement of Forensic Advisors in the Belgian criminal justice system.
Bitzer, Sonja
2018-04-01
Forensic Advisors at the National Institute for Criminalistics and Criminology in Brussels act as advising body to the magistrate regarding analytical possibilities and the usefulness of trace analysis in a case. Initially, their function was devised to assist in complex murder cases with unknown offender. However, in a previous study, the increasing diversity of the cases they are requested for has been observed (Bitzer et al., in press). In order to deepen our understanding of the decision steps in the criminal investigation process, the decision to involve a Forensic Advisor and the factors leading to their involvement were evaluated. The study focused on homicide, robbery and burglary cases with and without requests for a Forensic Advisor between January 2014 and June 2016. The factors were categorised into five knowledge dimensions: strategic, immediate, physical, criminal and utility. Decision tree modelling was carried out in order to identify the factors influencing the request for a Forensic Advisor in the case. The decision to request a Forensic Advisor differs between different types of offences. It also depends on the complexity of the case in terms of the number of traces and objects collected at the crime scene, and the availability of witness reports. Indeed, Forensic Advisors take the role of trace analysis coordinator by providing an overview of all available traces, objects, analyses and results. According to the principal implication factors and the performed case study, the contribution of Forensic Advisors consists mainly in summarising all information and advise on potential additional analyses. This might be explained by a loss of overview of the information and the possibilities regarding trace analysis by the magistrate responsible of the case. Copyright © 2018 Elsevier B.V. All rights reserved.
Data Partitioning and Load Balancing in Parallel Disk Systems
NASA Technical Reports Server (NTRS)
Scheuermann, Peter; Weikum, Gerhard; Zabback, Peter
1997-01-01
Parallel disk systems provide opportunities for exploiting I/O parallelism in two possible waves, namely via inter-request and intra-request parallelism. In this paper we discuss the main issues in performance tuning of such systems, namely striping and load balancing, and show their relationship to response time and throughput. We outline the main components of an intelligent, self-reliant file system that aims to optimize striping by taking into account the requirements of the applications and performs load balancing by judicious file allocation and dynamic redistributions of the data when access patterns change. Our system uses simple but effective heuristics that incur only little overhead. We present performance experiments based on synthetic workloads and real-life traces.
41 CFR 105-64.001 - What terms are defined in this part?
Code of Federal Regulations, 2010 CFR
2010-07-01
... but not limited to name or Social Security Number, from which the identity of the person can be... distinguish or trace an individual's identity, such as their name, Social Security Number, date and place of... connection with an individual's interaction with GSA. Request for access means a request by an individual to...
Timeliness of contact tracing among flight passengers for influenza A/H1N1 2009
2011-01-01
Background During the initial containment phase of influenza A/H1N1 2009, close contacts of cases were traced to provide antiviral prophylaxis within 48 h after exposure and to alert them on signs of disease for early diagnosis and treatment. Passengers seated on the same row, two rows in front or behind a patient infectious for influenza, during a flight of ≥ 4 h were considered close contacts. This study evaluates the timeliness of flight-contact tracing (CT) as performed following national and international CT requests addressed to the Center of Infectious Disease Control (CIb/RIVM), and implemented by the Municipal Health Services of Schiphol Airport. Methods Elapsed days between date of flight arrival and the date passenger lists became available (contact details identified - CI) was used as proxy for timeliness of CT. In a retrospective study, dates of flight arrival, onset of illness, laboratory diagnosis, CT request and identification of contacts details through passenger lists, following CT requests to the RIVM for flights landed at Schiphol Airport were collected and analyzed. Results 24 requests for CT were identified. Three of these were declined as over 4 days had elapsed since flight arrival. In 17 out of 21 requests, contact details were obtained within 7 days after arrival (81%). The average delay between arrival and CI was 3,9 days (range 2-7), mainly caused by delay in diagnosis of the index patient after arrival (2,6 days). In four flights (19%), contacts were not identified or only after > 7 days. CI involving Dutch airlines was faster than non-Dutch airlines (P < 0,05). Passenger locator cards did not improve timeliness of CI. In only three flights contact details were identified within 2 days after arrival. Conclusion CT for influenza A/H1N1 2009 among flight passengers was not successful for timely provision of prophylaxis. CT had little additional value for alerting passengers for disease symptoms, as this information already was provided during and after the flight. Public health authorities should take into account patient delays in seeking medical advise and laboratory confirmation in relation to maximum time to provide postexposure prophylaxis when deciding to install contact tracing measures. International standardization of CT guidelines is recommended. PMID:22204494
Development and analysis of SCR requirements tables for system scenarios
NASA Technical Reports Server (NTRS)
Callahan, John R.; Morrison, Jeffery L.
1995-01-01
We describe the use of scenarios to develop and refine requirement tables for parts of the Earth Observing System Data and Information System (EOSDIS). The National Aeronautics and Space Administration (NASA) is developing EOSDIS as part of its Mission-To-Planet-Earth (MTPE) project to accept instrument/platform observation requests from end-user scientists, schedule and perform requested observations of the Earth from space, collect and process the observed data, and distribute data to scientists and archives. Current requirements for the system are managed with tools that allow developers to trace the relationships between requirements and other development artifacts, including other requirements. In addition, the user community (e.g., earth and atmospheric scientists), in conjunction with NASA, has generated scenarios describing the actions of EOSDIS subsystems in response to user requests and other system activities. As part of a research effort in verification and validation techniques, this paper describes our efforts to develop requirements tables from these scenarios for the EOSDIS Core System (ECS). The tables specify event-driven mode transitions based on techniques developed by the Naval Research Lab's (NRL) Software Cost Reduction (SCR) project. The SCR approach has proven effective in specifying requirements for large systems in an unambiguous, terse format that enhance identification of incomplete and inconsistent requirements. We describe development of SCR tables from user scenarios and identify the strengths and weaknesses of our approach in contrast to the requirements tracing approach. We also evaluate the capabilities of both approach to respond to the volatility of requirements in large, complex systems.
I/O-aware bandwidth allocation for petascale computing systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhou, Zhou; Yang, Xu; Zhao, Dongfang
In the Big Data era, the gap between the storage performance and an appli- cation's I/O requirement is increasing. I/O congestion caused by concurrent storage accesses from multiple applications is inevitable and severely harms the performance. Conventional approaches either focus on optimizing an ap- plication's access pattern individually or handle I/O requests on a low-level storage layer without any knowledge from the upper-level applications. In this paper, we present a novel I/O-aware bandwidth allocation framework to coordinate ongoing I/O requests on petascale computing systems. The motivation behind this innovation is that the resource management system has a holistic view ofmore » both the system state and jobs' activities and can dy- namically control the jobs' status or allocate resource on the y during their execution. We treat a job's I/O requests as periodical subjobs within its lifecycle and transform the I/O congestion issue into a classical scheduling problem. Based on this model, we propose a bandwidth management mech- anism as an extension to the existing scheduling system. We design several bandwidth allocation policies with different optimization objectives either on user-oriented metrics or system performance. We conduct extensive trace- based simulations using real job traces and I/O traces from a production IBM Blue Gene/Q system at Argonne National Laboratory. Experimental results demonstrate that our new design can improve job performance by more than 30%, as well as increasing system performance.« less
Neutral Beam Injection in the JET Trace Tritium Experiment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Surrey, E.; Ciric, D.; Cox, S. J.
Operation of the JET Neutral Beam Injectors with tritium is described. Supplying the tritium feed via the special electrically grounded gas feed compromised the performance of the up-graded high current triode Positive Ion Neutral Injectors (PINI) due to gas starvation of the source and the methods adopted to ameliorate this effect are described. A total of 362 PINI beam pulses were requested, circulating a total of 4.73g tritium, of which 9.3mg was injected into the torus. Safety considerations required a continuous, cumulative total to be maintained of the mass of tritium adsorbed onto the cryo-pumping panel; a daily limit ofmore » 0.5g was adopted for the Trace Tritium Experiment (TTE). A subsequent clean up phase using 115keV deuterium beams completed the isotopic exchange of components in the beamline.« less
dos Santos Mota, Ananda; Morais Monteiro, Priscila; Carvalho, Angela Cristina Gouvêa; Fernandes Diniz, Barbara; Gemal Lanzieri, Pedro; Carneiro Ramos, Ricardo; Mocarzel, Luis Otavio
2017-01-01
Diarrhea is one of the most common symptoms in common variable immunodeficiency, but neurologic manifestations are rare. We presented a 50-year-old woman with recurrent diarrhea and severe weight loss that developed a posterior cord syndrome. Endoscopy found a duodenal villous blunting, intraepithelial lymphocytosis, and lack of plasma cells and magnetic resonance imaging of the spine was normal. Laboratory assays confirmed common variable immunodeficiency syndrome and showed low levels of trace elements (copper and zinc). Treatment was initiated with parenteral replacement of trace elements and intravenous human immunoglobulin and the patient improved clinically. In conclusion, physicians must be aware that gastrointestinal and neurologic disorders may be related to each other and remember to request trace elements laboratory assessment. PMID:28356913
ExoMars Trace Gas Orbiter Instrument Modelling Approach to Streamline Science Operations
NASA Astrophysics Data System (ADS)
Munoz Fernandez, Michela; Frew, David; Ashman, Michael; Cardesin Moinelo, Alejandro; Garcia Beteta, Juan Jose; Geiger, Bernhard; Metcalfe, Leo; Nespoli, Federico; Muniz Solaz, Carlos
2018-05-01
ExoMars Trace Gas Orbiter (TGO) science operations activities are centralised at ESAC's Science Operations Centre (SOC). The SOC receives the inputs from the principal investigators (PIs) in order to implement and deliver the spacecraft pointing requests and instrument timelines to the Mission Operations Centre (MOC). The high number of orbits per planning cycle has made it necessary to abstract the planning interactions between the SOC and the PI teams at the observation level. This paper describes the modelling approach we have conducted for TGOÃs instruments to streamline science operations. We have created dynamic observation types that scale to adapt to the conditions specified by the PI teams including observation timing, and pointing block parameters calculated from observation geometry. This approach is considered and improvement with respect to previous missions where the generation of the observation pointing and commanding requests was performed manually by the instrument teams. Automation software assists us to effectively handle the high density of planned orbits with increasing volume of scientific data and to successfully meet opportunistic scientific goals and objectives. Our planning tool combines the instrument observation definition files provided by the PIs together with the flight dynamics products to generate the Pointing Requests and the instrument timeline (ITL). The ITL contains all the validated commands at the TC sequence level and computes the resource envelopes (data rate, power, data volume) within the constraints. At the SOC, our main goal is to maximise the science output while minimising the number of iterations among the teams, ensuring that the timeline does not violate the state transitions allowed in the Mission Operations Rules and Constraints Document.
Cost-aware request routing in multi-geography cloud data centres using software-defined networking
NASA Astrophysics Data System (ADS)
Yuan, Haitao; Bi, Jing; Li, Bo Hu; Tan, Wei
2017-03-01
Current geographically distributed cloud data centres (CDCs) require gigantic energy and bandwidth costs to provide multiple cloud applications to users around the world. Previous studies only focus on energy cost minimisation in distributed CDCs. However, a CDC provider needs to deliver gigantic data between users and distributed CDCs through internet service providers (ISPs). Geographical diversity of bandwidth and energy costs brings a highly challenging problem of how to minimise the total cost of a CDC provider. With the recently emerging software-defined networking, we study the total cost minimisation problem for a CDC provider by exploiting geographical diversity of energy and bandwidth costs. We formulate the total cost minimisation problem as a mixed integer non-linear programming (MINLP). Then, we develop heuristic algorithms to solve the problem and to provide a cost-aware request routing for joint optimisation of the selection of ISPs and the number of servers in distributed CDCs. Besides, to tackle the dynamic workload in distributed CDCs, this article proposes a regression-based workload prediction method to obtain future incoming workload. Finally, this work evaluates the cost-aware request routing by trace-driven simulation and compares it with the existing approaches to demonstrate its effectiveness.
GENERATION AND CONTROL OF AIR POLLUTANTS FROM ORIMULSION (R) COMBUSTION
The paper discusses a study requested in 1997 by the U.S. Congress to provide technical information regarding Orimulsion (R) and its environmental impacts. (NOTE: Orimulsion is an emulsified fuel, composed of approximately 70% Venezuelan bitumen, 30% water, and trace amounts of ...
Characterizing parallel file-access patterns on a large-scale multiprocessor
NASA Technical Reports Server (NTRS)
Purakayastha, Apratim; Ellis, Carla Schlatter; Kotz, David; Nieuwejaar, Nils; Best, Michael
1994-01-01
Rapid increases in the computational speeds of multiprocessors have not been matched by corresponding performance enhancements in the I/O subsystem. To satisfy the large and growing I/O requirements of some parallel scientific applications, we need parallel file systems that can provide high-bandwidth and high-volume data transfer between the I/O subsystem and thousands of processors. Design of such high-performance parallel file systems depends on a thorough grasp of the expected workload. So far there have been no comprehensive usage studies of multiprocessor file systems. Our CHARISMA project intends to fill this void. The first results from our study involve an iPSC/860 at NASA Ames. This paper presents results from a different platform, the CM-5 at the National Center for Supercomputing Applications. The CHARISMA studies are unique because we collect information about every individual read and write request and about the entire mix of applications running on the machines. The results of our trace analysis lead to recommendations for parallel file system design. First the file system should support efficient concurrent access to many files, and I/O requests from many jobs under varying load conditions. Second, it must efficiently manage large files kept open for long periods. Third, it should expect to see small requests predominantly sequential access patterns, application-wide synchronous access, no concurrent file-sharing between jobs appreciable byte and block sharing between processes within jobs, and strong interprocess locality. Finally, the trace data suggest that node-level write caches and collective I/O request interfaces may be useful in certain environments.
Resource Management Scheme Based on Ubiquitous Data Analysis
Lee, Heung Ki; Jung, Jaehee
2014-01-01
Resource management of the main memory and process handler is critical to enhancing the system performance of a web server. Owing to the transaction delay time that affects incoming requests from web clients, web server systems utilize several web processes to anticipate future requests. This procedure is able to decrease the web generation time because there are enough processes to handle the incoming requests from web browsers. However, inefficient process management results in low service quality for the web server system. Proper pregenerated process mechanisms are required for dealing with the clients' requests. Unfortunately, it is difficult to predict how many requests a web server system is going to receive. If a web server system builds too many web processes, it wastes a considerable amount of memory space, and thus performance is reduced. We propose an adaptive web process manager scheme based on the analysis of web log mining. In the proposed scheme, the number of web processes is controlled through prediction of incoming requests, and accordingly, the web process management scheme consumes the least possible web transaction resources. In experiments, real web trace data were used to prove the improved performance of the proposed scheme. PMID:25197692
Design issues and caching strategies for CD-ROM-based multimedia storage
NASA Astrophysics Data System (ADS)
Shastri, Vijnan; Rajaraman, V.; Jamadagni, H. S.; Venkat-Rangan, P.; Sampath-Kumar, Srihari
1996-03-01
CD-ROMs have proliferated as a distribution media for desktop machines for a large variety of multimedia applications (targeted for a single-user environment) like encyclopedias, magazines and games. With CD-ROM capacities up to 3 GB being available in the near future, they will form an integral part of Video on Demand (VoD) servers to store full-length movies and multimedia. In the first section of this paper we look at issues related to the single- user desktop environment. Since these multimedia applications are highly interactive in nature, we take a pragmatic approach, and have made a detailed study of the multimedia application behavior in terms of the I/O request patterns generated to the CD-ROM subsystem by tracing these patterns. We discuss prefetch buffer design and seek time characteristics in the context of the analysis of these traces. We also propose an adaptive main-memory hosted cache that receives caching hints from the application to reduce the latency when the user moves from one node of the hyper graph to another. In the second section we look at the use of CD-ROM in a VoD server and discuss the problem of scheduling multiple request streams and buffer management in this scenario. We adapt the C-SCAN (Circular SCAN) algorithm to suit the CD-ROM drive characteristics and prove that it is optimal in terms of buffer size management. We provide computationally inexpensive relations by which this algorithm can be implemented. We then propose an admission control algorithm which admits new request streams without disrupting the continuity of playback of the previous request streams. The algorithm also supports operations such as fast forward and replay. Finally, we discuss the problem of optimal placement of MPEG streams on CD-ROMs in the third section.
ERIC Educational Resources Information Center
Griffin, Melanie; Schmidt, LeEtta
2017-01-01
This article explores the implementation of special collections interlibrary loan policies and procedures at the University of South Florida (USF), focusing particularly on the development of policies related to physically loaning published materials, and traces the development of these policies through a pilot project to routinized…
Input/output behavior of supercomputing applications
NASA Technical Reports Server (NTRS)
Miller, Ethan L.
1991-01-01
The collection and analysis of supercomputer I/O traces and their use in a collection of buffering and caching simulations are described. This serves two purposes. First, it gives a model of how individual applications running on supercomputers request file system I/O, allowing system designer to optimize I/O hardware and file system algorithms to that model. Second, the buffering simulations show what resources are needed to maximize the CPU utilization of a supercomputer given a very bursty I/O request rate. By using read-ahead and write-behind in a large solid stated disk, one or two applications were sufficient to fully utilize a Cray Y-MP CPU.
Cornelis, R; Fuentes-Arderiu, X; Bruunshuus, I; Templeton, D
1997-12-10
This document is the first recommendation on the presentation of trace elements and their values in clinical laboratory sciences from IFCC and IUPAC. It forms part of the ongoing effort to standardize requests and reporting of laboratory data for transmission across cultural and linguistic domains, without attempting to standardize the language used by clinicians and laboratory practitioners. Subsequent documents deal with syntax, kinds-of-property, and properties and units used in other areas of clinical laboratory sciences.
ERIC Educational Resources Information Center
Nikica Mojsoska-Blazevski, Nikica
2017-01-01
This report presents the findings of the first nationwide tracer study conducted in the former Yugoslav Republic of Macedonia. The study was conducted as part of the World Bank's project Skills Development and Innovation Support, within the component focused on developing a Skills Observatory. At the request of the Ministry of Education and…
ERIC Educational Resources Information Center
Morris, Marilyn L.; Dye, Charles M.
The history of the Chapman College Residence Education Center (REC) System is traced from 1958 to 1982. After experimenting near its home campus in Orange, California, the program has grown to 41 centers in California and eight other states, including the Navy's shipboard PACE program. In 1958 the college met the request of students at nearby El…
The Evolution of Random Number Generation in MUVES
2017-01-01
mathematical basis and statistical justification for algorithms used in the code. The working code provided produces results identical to the current...MUVES, includ- ing the mathematical basis and statistical justification for algorithms used in the code. The working code provided produces results...questionable numerical and statistical properties. The development of the modern system is traced through software change requests, resulting in a random number
Requests from professional care providers for consultation with palliative care consultation teams.
Groot, Marieke M; Vernooij-Dassen, Myrra J F J; Courtens, Annemie M; Kuin, Annemieke; van der Linden, Barbara A; van Zuylen, Lia; Crul, Ben J P; Grol, Richard P T M
2005-11-01
Professional care providers need a substantial basis of competence and expertise to provide appropriate palliative care. Little is known about the problems professionals experience in their palliative care provision in daily practice or about the nature of the advice and support they request from experts. Our aim was to investigate the extent to which professionals requested assistance from palliative care consultation teams and the reasons behind these requests to trace any gaps they experience in the provision of palliative care. As part of a large national palliative care development programme, we studied requests for consultation made by professional care providers over a 2-year period. The requests for consultation were recorded on a specially developed standard registration form and classified according to 11 domains relevant to palliative care. Professional care providers requested 4351 consultations on account of 8413 specific problems in 11 quality-of-life and quality-of-care domains. The distribution of problems over these domains was unbalanced: 42.2% of the specific problems were physical, while the percentages of psychological, pharmacological and organizational problems were 7.7, 12.5 and 12.8%, respectively. In contrast, issues of a spiritual nature or concerned with daily functioning were raised infrequently (1.1 and 0.9%). Details of the specific problems in all the domains are described in the text and tables. The results of our study form a valid basis on which to develop and implement improvements in palliative care. We recommend that future well-founded policies for palliative care should incorporate palliative care consultation as well as educational and organizational interventions.
Naftz, David L.; Ranalli, Anthony J.; Rowland, Ryan C.; Marston, Thomas M.
2011-01-01
In 2007, the Ute Mountain Ute Tribe requested that the U.S. Environmental Protection Agency and U.S. Geological Survey conduct an independent evaluation of potential offsite migration of radionuclides and selected trace elements associated with the ore storage and milling process at an active uranium mill site near White Mesa, Utah. Specific objectives of this study were (1) to determine recharge sources and residence times of groundwater surrounding the mill site, (2) to determine the current concentrations of uranium and associated trace elements in groundwater surrounding the mill site, (3) to differentiate natural and anthropogenic contaminant sources to groundwater resources surrounding the mill site, (4) to assess the solubility and potential for offsite transport of uranium-bearing minerals in groundwater surrounding the mill site, and (5) to use stream sediment and plant material samples from areas surrounding the mill site to identify potential areas of offsite contamination and likely contaminant sources.
Huang, Yu-an; Zhou, Fang-qin; Long, Si-hua; Yang, Liu
2004-02-01
The effects on gallium atomization in the pyrolytic graphite tube imposed by different matrix modifiers and different coatings were discussed detailedly in this paper. In the presence of matrix modifier of Ni(NO3)2 the matrix interference was eliminated efficiently. The pyrolytic graphite tubes were coated differently with lanthanum, zirconium, and molybdenum to avoid producing gallium carbide. Results showed that the tube with molybdenum coating was the best. On this basis, the mechanism of gallium atomization in the molybdenum-coated pyrolytic graphite tube using Ni(NO3)2 as a matrix modifier was studied furthermore; in addition, the parameters of the operation were optimized. As a result, a new method improved in many aspects was developed to detect trace gallium in complicated sample of gangue. The outcomes of practical applications indicated that the method could satisfy the requests of analysis and that the manipulations were simple to achieve. The characteristic content, the detection limit, and the adding recoveries were 2.12 x 10(-11) g, 1.4 x 10(-10) g and 97.4%-102.7% respectively, and the relative standard deviation was less than or equal to 3.6% (n = 11).
CPU Performance Counter-Based Problem Diagnosis for Software Systems
2009-09-01
application servers and implementation techniques), this thesis only used the Enterprise Java Bean (EJB) SessionBean version of RUBiS. The PHP and Servlet ...collection statistics at the Java Virtual Machine (JVM) level can be reused for any Java application. Other examples of gray-box instrumentation include path...used gray-box approaches. For example, PinPoint [11, 14] and [29] use request tracing to diagnose Java exceptions, endless calls, and null calls in
Topical index and bibliography of U.S. Geological Survey Trace Elements and related reports
Curtis, Diane; Houser, Shirley S.
1952-01-01
Part 1, the topical index, lists the titles of reports prepared from 1941 to December 1952, in conjunction with the Geological Survey's program of uranium and other elements of related interest. It includes not only completed Trace Elements reports and those now in preparation, but also Survey publications, publications by Survey personnel in scientific journals, and open-fie releases. The titles are grouped topically under the headings listed in the table of contents. Entries in each category are listed alphabetically, by author, and numbered consecutively. Many of the reports have been cross-indexed, where appropriate. The classification of the Trace Elements reports, insofar as it is known, has been indicated after the title of the report. The classification of some of the earlier Trace Elements reports is uncertain. The Geological Survey does not have additional copies of most of the reports listed, but copies of some of the completed reports can be loaned on request to organizations officially cooperating with the Atomic Energy Commission. Many Trace Elements reports have been made available to the public, either by open-file release, reproduction by Technical Information Service, Oak Ridge (referred to as TIS), by publication as a Geological Survey circular or bulletin or by a publication in a scientific journal. This information is given, following the title of the report. If the abstract of a Trace Element report has been published in Nuclear Science Abstracts, it is noted by the initials NSA following the title of the report. Part 2 is a reference guide to information on the Trace Elements program that is available to the public. This information is categorized according to the type of publication or release.
Final report of the SIM.QM-S8 supplementary comparison, trace metals in drinking water
NASA Astrophysics Data System (ADS)
Yang, Lu; Nadeau, Kenny; Gedara Pihillagawa, Indu; Meija, Juris; Mester, Zoltan; Napoli, Romina; Pérez Zambra, Ramiro; Ferreira, Elizabeth; Alejandro Ahumada Forigua, Diego; Abella Gamba, Johanna Paola
2018-01-01
After completing a supplementary comparison SIM.QM-S7, the National Metrology Institute of Colombia (NMIC) requested to National Research Council of Canada (NRC) a subsequent bilateral comparison, because INMC considered that its results in SIM.QM-S7 unrepresentative of its standards. In this context, NRC agreed to coordinate this bilateral comparison with the aim of demonstrating the measurement capabilities of trace elements in fresh water. Participants included NMIC and LATU. No measurement method was prescribed by the coordinating laboratory. Therefore, NMIs used measurement methods of their choice. However, the majority of NMIs/DIs used ICP-MS. This SIM.QM-S8 Supplementary Comparison provides NMIs with the needed evidence for CMC claims for trace elements in fresh waters and similar matrices. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Digital Load Control Applied to Full-Scale Airframe Fatigue Tests
1979-05-01
CONTINUED) WAIT 1 TICK 1/60 SECOND 152 AFFDL-TR-79-3011 FUNCTION ICHECK START DECLARE COMMON AREAS DEFINE SWITCH PATTERNS FOR KILL & MOLD OPTIONAL...TRACE FEATURE RESET ICHECK 0 YES ET IHECKES- KILL OR HOLD ? " ANYBAKRUDRQET? ISYES RETURNAR 5PROGRAMNO RUNNABLE ? 53 AFFDL-TR-79-3011 SUBROUTINE IAIR (I...RETURN C C ERROR RETURNS 998 IDRTR=-i RETURN END C C FUNCTION ICHECK C PURPOSE IS TO CHECK FOR C KILL, STOP, GO REQUESTS FROM CONSOLE OR BUTTONS C AND
Dynamic file-access characteristics of a production parallel scientific workload
NASA Technical Reports Server (NTRS)
Kotz, David; Nieuwejaar, Nils
1994-01-01
Multiprocessors have permitted astounding increases in computational performance, but many cannot meet the intense I/O requirements of some scientific applications. An important component of any solution to this I/O bottleneck is a parallel file system that can provide high-bandwidth access to tremendous amounts of data in parallel to hundreds or thousands of processors. Most successful systems are based on a solid understanding of the expected workload, but thus far there have been no comprehensive workload characterizations of multiprocessor file systems. This paper presents the results of a three week tracing study in which all file-related activity on a massively parallel computer was recorded. Our instrumentation differs from previous efforts in that it collects information about every I/O request and about the mix of jobs running in a production environment. We also present the results of a trace-driven caching simulation and recommendations for designers of multiprocessor file systems.
Fast Flux Watch: A mechanism for online detection of fast flux networks.
Al-Duwairi, Basheer N; Al-Hammouri, Ahmad T
2014-07-01
Fast flux networks represent a special type of botnets that are used to provide highly available web services to a backend server, which usually hosts malicious content. Detection of fast flux networks continues to be a challenging issue because of the similar behavior between these networks and other legitimate infrastructures, such as CDNs and server farms. This paper proposes Fast Flux Watch (FF-Watch), a mechanism for online detection of fast flux agents. FF-Watch is envisioned to exist as a software agent at leaf routers that connect stub networks to the Internet. The core mechanism of FF-Watch is based on the inherent feature of fast flux networks: flux agents within stub networks take the role of relaying client requests to point-of-sale websites of spam campaigns. The main idea of FF-Watch is to correlate incoming TCP connection requests to flux agents within a stub network with outgoing TCP connection requests from the same agents to the point-of-sale website. Theoretical and traffic trace driven analysis shows that the proposed mechanism can be utilized to efficiently detect fast flux agents within a stub network.
EARS: Electronic Access to Reference Service.
Weise, F O; Borgendale, M
1986-01-01
Electronic Access to Reference Service (EARS) is a front end to the Health Sciences Library's electronic mail system, with links to the online public catalog. EARS, which became operational in September 1984, is accessed by users at remote sites with either a terminal or microcomputer. It is menu-driven, allowing users to request: a computerized literature search, reference information, a photocopy of a journal article, or a book. This paper traces the history of EARS and discusses its use, its impact on library staff and services, and factors that influence the diffusion of new technology. PMID:3779167
EARS: Electronic Access to Reference Service.
Weise, F O; Borgendale, M
1986-10-01
Electronic Access to Reference Service (EARS) is a front end to the Health Sciences Library's electronic mail system, with links to the online public catalog. EARS, which became operational in September 1984, is accessed by users at remote sites with either a terminal or microcomputer. It is menu-driven, allowing users to request: a computerized literature search, reference information, a photocopy of a journal article, or a book. This paper traces the history of EARS and discusses its use, its impact on library staff and services, and factors that influence the diffusion of new technology.
Differential Effects of the Cannabinoid Agonist WIN55,212-2 on Delay and Trace Eyeblink Conditioning
Steinmetz, Adam B.; Freeman, John H.
2014-01-01
Central cannabinoid-1 receptors (CB1R) play a role in the acquisition of delay eyeblink conditioning but not trace eyeblink conditioning in humans and animals. However, it is not clear why trace conditioning is immune to the effects of cannabinoid receptor compounds. The current study examined the effects of variants of delay and trace conditioning procedures to elucidate the factors that determine the effects of CB1R agonists on eyeblink conditioning. In Experiment 1 rats were administered the cannabinoid agonist WIN55,212-2 during delay, long delay, or trace conditioning. Rats were impaired during delay and long delay but not trace conditioning; the impairment was greater for long delay than delay conditioning. Trace conditioning was further examined in Experiment 2 by manipulating the trace interval and keeping constant the conditioned stimulus (CS) duration. It was found that when the trace interval was 300 ms or less WIN55,212-2 administration impaired the rate of learning. Experiment 3 tested whether the trace interval duration or the relative durations of the CS and trace interval were critical parameters influencing the effects of WIN55,212-2 on eyeblink conditioning. Rats were not impaired with a 100 ms CS, 200 ms trace paradigm but were impaired with a 1000 ms CS, 500 ms trace paradigm, indicating that the duration of the trace interval does not matter but the proportion of the interstimulus interval occupied by the CS relative to the trace period is critical. Taken together the results indicate that cannabinoid agonists affect cerebellar learning the CS is longer than the trace interval. PMID:24128358
Hagerman, Amy D; Ward, Michael P; Anderson, David P; Looney, J Chris; McCarl, Bruce A
2013-07-01
In this study our aim was to value the benefits of rapid effective trace-back capability-based on a livestock identification system - in the event of a foot and mouth disease (FMD) outbreak. We simulated an FMD outbreak in the Texas High Plains, an area of high livestock concentration, beginning in a large feedlot. Disease spread was simulated under different time dependent animal tracing scenarios. In the specific scenario modeled (incursion of FMD within a large feedlot, detection within 14 days and 90% effective tracing), simulation suggested that control costs of the outbreak significantly increase if tracing does not occur until day 10 as compared to the baseline of tracing on day 2. In addition, control costs are significantly increased if effectiveness were to drop to 30% as compared to the baseline of 90%. Results suggest potential benefits from rapid effective tracing in terms of reducing government control costs; however, a variety of other scenarios need to be explored before determining in which situations rapid effective trace-back capability is beneficial. Copyright © 2012 Elsevier B.V. All rights reserved.
Health-hazard-evaluation report MHETA 89-362-2027, Helen Mining Company, Homer City, Pennsylvania
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ferguson, R.P.
1990-03-01
In response to a request from the United Mine Workers of America, an investigation was made of possible hazardous working conditions at the Helen Mining Company, Homer City, Pennsylvania. One of the tipple operators had complained of headaches, dizziness and skin rashes from working with a mixture of solvents used in the float/sink test operation. The solvents included perchloroethylene and dibromomethane. A week prior to receiving the request, the use of dibromomethane had been discontinued. Consequently, on the visit to the site, no traces of dibromomethane were found. After engineering controls were installed, only one of seven personal breathing zonemore » samples detected any perchloroethylene, and that sample was 0.12 parts per million, at the limit of detection. The author concludes that a hazard from perchloroethylene did not exist at the time of the evaluation. The author recommends replacing the rubber/cloth type glove being used with either a Teflon or Viton glove, and enclosing the work table.« less
ERIC Educational Resources Information Center
Terrier, Lohyd; Joule, Robert-Vincent; Marfaing, Benedicte
2011-01-01
The door-in-the-face technique (Cialdini, Vincent, Lewis, Catalan, Wheeler & Darby, 1975) increases the likelihood that subjects will comply with a target request after they have been submitted first to a request too costly to for agreement. This study tests the effects of the requester's acceptance versus non-acceptance of the refusal of the…
Management of cosmic radiation exposure for aircraft crew in Japan.
Yasuda, Hiroshi; Sato, Tatsuhiko; Yonehara, Hidenori; Kosako, Toshiso; Fujitaka, Kazunobu; Sasaki, Yasuhito
2011-07-01
The International Commission on Radiological Protection has recommended that cosmic radiation exposure of crew in commercial jet aircraft be considered as occupational exposure. In Japan, the Radiation Council of the government has established a guideline that requests domestic airlines to voluntarily keep the effective dose of cosmic radiation for aircraft crew below 5 mSv y(-1). The guideline also gives some advice and policies regarding the method of cosmic radiation dosimetry, the necessity of explanation and education about this issue, a way to view and record dose data, and the necessity of medical examination for crew. The National Institute of Radiological Sciences helps the airlines to follow the guideline, particularly for the determination of aviation route doses by numerical simulation. The calculation is performed using an original, easy-to-use program package called 'JISCARD EX' coupled with a PHITS-based analytical model and a GEANT4-based particle tracing code. The new radiation weighting factors recommended in 2007 are employed for effective dose determination. The annual individual doses of aircraft crew were estimated using this program.
Effects of Maryland's law banning Saturday night special handguns on crime guns
Vernick, J.; Webster, D.; Hepburn, L.
1999-01-01
Objectives—To determine the effects of a 1988 Maryland law that banned "Saturday night special" handguns on the types of guns used in crime. To determine if controls on the lawful market for handguns affect the illegal market as well. Setting—Baltimore, Maryland, and 15 other US cities participating in a crime gun tracing project. Methods—Cross sectional comparison of the proportion of crime guns that are banned by the Maryland law, comparing Baltimore, MD with 15 other cities outside of Maryland. Multivariate linear regression analysis to determine if observed differences between Baltimore and 15 other cities are explained by demographic or regional differences among the cities rather than Maryland's law. Results—Among crime guns, a gun banned by Maryland's law is more than twice as likely (relative risk (RR) 2.3, 95% confidence interval (CI) 2.0 to 2.5) to be the subject of a crime gun trace request in 15 other cities combined, than in Baltimore. Among homicide guns, a crime especially relevant for public safety, a comparable difference (RR 2.1, 95% CI 1.1 to 4.2) was observed. The proportion of Baltimore's crime guns that are banned is 12 percentage points lower than would be expected based on its demographic and regional characteristics alone. Among crime guns purchased after 1990, a much smaller proportion in Baltimore are banned models than in 15 other cities. Conclusions—Maryland's law has reduced the use of banned Saturday night specials by criminals in Baltimore. Contrary to the claims of some opponents of gun control laws, regulation of the lawful market for firearms can also affect criminals. PMID:10628912
Systematic sparse matrix error control for linear scaling electronic structure calculations.
Rubensson, Emanuel H; Sałek, Paweł
2005-11-30
Efficient truncation criteria used in multiatom blocked sparse matrix operations for ab initio calculations are proposed. As system size increases, so does the need to stay on top of errors and still achieve high performance. A variant of a blocked sparse matrix algebra to achieve strict error control with good performance is proposed. The presented idea is that the condition to drop a certain submatrix should depend not only on the magnitude of that particular submatrix, but also on which other submatrices that are dropped. The decision to remove a certain submatrix is based on the contribution the removal would cause to the error in the chosen norm. We study the effect of an accumulated truncation error in iterative algorithms like trace correcting density matrix purification. One way to reduce the initial exponential growth of this error is presented. The presented error control for a sparse blocked matrix toolbox allows for achieving optimal performance by performing only necessary operations needed to maintain the requested level of accuracy. Copyright 2005 Wiley Periodicals, Inc.
Early social-emotional development in blind infants.
Tröster, H; Brambring, M
1992-01-01
In order to study the impact of blindness on social and emotional development during the first year of life, the level of social-emotional development was compared in blind and sighted 9- and 12-month-old infants. The five 9-month-old and the 17 12-month-old blind infants were completely blind from birth and exhibited no further serious disabilities. Social-emotional development was assessed with a scale from the Bielefeld Developmental Test for Blind Infants and Preschoolers containing three subscales on emotions, social interaction and impulse control. Compared to non-disabled infants, blind infants exhibited a more limited repertoire of facial expressions and less responsiveness. They less frequently attempted to initiate contact with their mothers (self-initiated interactions) or comply with simple requests and prohibitions than sighted infants. These differences in the social-emotional development of blind and sighted infants are traced back to the effects of blindness on the mother-child interaction. The lack of visual perception appears to impede particularly the acquisition of a dialogue concept.
Pezze, Marie-Astrid; Marshall, Hayley J; Cassaday, Helen J
2017-06-28
The muscarinic acetylcholine receptor is an important modulator of medial prefrontal cortex (mPFC) functions, such as the working memory required to bridge a trace interval in associative leaning. Aversive and appetitive trace conditioning procedures were used to examine the effects of scopolamine (0.1 and 0.5 mg/kg, i.p.) in male rats. Follow-up experiments tested the effects of microinfusion of 0.15 μg of scopolamine (0.075 μg of in 0.5 μl/side) in infralimbic (IL) versus prelimbic regions of rat mPFC, in appetitive trace and locomotor activity (LMA) procedures. Systemic scopolamine was without effect in an aversive trace conditioning procedure, but impaired appetitive conditioning at a 2 s trace interval. This effect was demonstrated as reduced responding during presentations of the conditioned stimulus (CS) and during the interstimulus interval (ISI). There was no such effect on responding during food (unconditioned stimulus, US) responding or in the intertrial interval (ITI). In contrast, systemic scopolamine dose-relatedly increased LMA. Trace conditioning was similarly impaired at the 2 s trace (shown as reduced responding to the CS and during the ISI, but not during US presentations or in the ITI) after infusion in mPFC, whereas LMA was increased (after infusion in IL only). Therefore, our results point to the importance of cholinergic modulation in mPFC for trace conditioning and show that the observed effects cannot be attributed to reduced activity. SIGNIFICANCE STATEMENT Events are very often separated in time, in which case working memory is necessary to condition their association in "trace conditioning." The present study used conditioning variants motivated aversively with foot shock and appetitively with food. The drug scopolamine was used to block muscarinic acetylcholine receptors involved in working memory. The results show that reduced cholinergic transmission in medial prefrontal cortex (mPFC) impaired appetitive trace conditioning at a 2 s trace interval. However, scopolamine was without effect in the aversive procedure, revealing the importance of procedural differences to the demonstration of the drug effect. The finding that blockade of muscarinic receptors in mPFC impaired trace conditioning shows that these receptors are critical modulators of short-term working memory. Copyright © 2017 Pezze et al.
Pezze, Marie-Astrid; Marshall, Hayley J.
2017-01-01
The muscarinic acetylcholine receptor is an important modulator of medial prefrontal cortex (mPFC) functions, such as the working memory required to bridge a trace interval in associative leaning. Aversive and appetitive trace conditioning procedures were used to examine the effects of scopolamine (0.1 and 0.5 mg/kg, i.p.) in male rats. Follow-up experiments tested the effects of microinfusion of 0.15 μg of scopolamine (0.075 μg of in 0.5 μl/side) in infralimbic (IL) versus prelimbic regions of rat mPFC, in appetitive trace and locomotor activity (LMA) procedures. Systemic scopolamine was without effect in an aversive trace conditioning procedure, but impaired appetitive conditioning at a 2 s trace interval. This effect was demonstrated as reduced responding during presentations of the conditioned stimulus (CS) and during the interstimulus interval (ISI). There was no such effect on responding during food (unconditioned stimulus, US) responding or in the intertrial interval (ITI). In contrast, systemic scopolamine dose-relatedly increased LMA. Trace conditioning was similarly impaired at the 2 s trace (shown as reduced responding to the CS and during the ISI, but not during US presentations or in the ITI) after infusion in mPFC, whereas LMA was increased (after infusion in IL only). Therefore, our results point to the importance of cholinergic modulation in mPFC for trace conditioning and show that the observed effects cannot be attributed to reduced activity. SIGNIFICANCE STATEMENT Events are very often separated in time, in which case working memory is necessary to condition their association in “trace conditioning.” The present study used conditioning variants motivated aversively with foot shock and appetitively with food. The drug scopolamine was used to block muscarinic acetylcholine receptors involved in working memory. The results show that reduced cholinergic transmission in medial prefrontal cortex (mPFC) impaired appetitive trace conditioning at a 2 s trace interval. However, scopolamine was without effect in the aversive procedure, revealing the importance of procedural differences to the demonstration of the drug effect. The finding that blockade of muscarinic receptors in mPFC impaired trace conditioning shows that these receptors are critical modulators of short-term working memory. PMID:28559376
Bershetyn, Anna; Odeny, Thomas A; Lyamuya, Rita; Nakiwogga-Muwanga, Alice; Diero, Lameck; Bwana, Mwebesa; Braitstein, Paula; Somi, Geoffrey; Kambugu, Andrew; Bukusi, Elizabeth; Hartogensis, Wendy; Glidden, David V; Wools-Kaloustian, Kara; Yiannoutsos, Constantin; Martin, Jeffrey; Geng, Elvin H
2017-06-01
The effect of tracing human immunodeficiency virus (HIV)-infected patients who are lost to follow-up (LTFU) on reengagement has not been rigorously assessed. We carried out an ex post analysis of a surveillance study in which LTFU patients were randomly selected for tracing to identify the effect of tracing on reengagement. We evaluated HIV-infected adults on antiretroviral therapy who were LTFU (>90 days late for last visit) at 14 clinics in Uganda, Kenya, and Tanzania. A random sample of LTFU patients was selected for tracing by peer health workers. We assessed the effect of selection for tracing using Kaplan-Meier estimates of reengagement among all patients as well as the subset of LTFU patients who were alive, contacted in person by the tracer, and out of care. Of 5781 eligible patients, 991 (17%) were randomly selected for tracing. One year after selection for tracing, 13.3% (95% confidence interval [CI], 11.1%-15.3%) of those selected for tracing returned compared with 10.0% (95% CI, 9.1%-10.8%) of those not randomly selected, an adjusted risk difference of 3.0% (95% CI, .7%-5.3%). Among patients found to be alive, personally contacted, and out of care, tracing increased the absolute probability of return at 1 year by 22% (95% CI, 7.1%-36.2%). The effect of tracing on rate of return to clinic decayed with a half-life of 7.0 days after tracing (95% CI, 2.6 %-12.9%). Tracing interventions increase reengagement, but developing methods for targeting LTFU patients most likely to benefit can make this practice more efficient. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
The introduction of forensic advisors in Belgium and their role in the criminal justice system.
Bitzer, Sonja; Heudt, Laetitia; Barret, Aurélie; George, Lore; Van Dijk, Karolien; Gason, Fabrice; Renard, Bertrand
2018-05-01
Forensic advisors (FA) at the National Institute for Criminalistics and Criminology (NICC), generalists in forensic science, act as an advising body to the magistrate to improve communication between the various parties involved in the investigation: magistrate, police and crime scene investigators, and forensic experts. Their role is manifold, but their main objectives are to optimise trace processing by selecting the most pertinent traces in the context of the case and by advising magistrates on the feasibility of forensic analyses in particular circumstances in regards to the latest technical advances. Despite the absence of a legal framework governing their role and involvement in judicial cases, the demand for their services has increased over the years. Initially, forensic advisors were called for complex homicide cases. Due to the proximity with the Public Prosecutor's Office, the types of offences for which their expertise was sought have become more diverse (mainly including robbery, burglary and sexual assault cases), leading to a diversity in the types of cases handled by the forensic advisors (complex, simple and review). In many of the cases they are requested for, in addition to consulting on the best analytical strategy, forensic advisors also assume the role of case coordinator regarding the seized objects and their respective analyses. Indeed, in the majority of cases treated by the FAs, two or more types of expertise have been requested and performed, either at the internal laboratories of NICC or at external laboratories. This paper explains the role of the forensic advisors in Belgium, the path that let to their current status and problems encountered. Copyright © 2017 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.
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Orejuela, Francisco J; Garcia, Tiffany; Green, Charles; Kilpatrick, Charlie; Guzman, Sara; Blackwell, Sean
2012-04-01
Ethnic disparities in labor pain management exist. Our purpose is to identify patients' attitudes and beliefs about epidural analgesia in order to develop a culturally competent educational intervention. A prospective observational study was conducted in patients admitted for vaginal delivery between July 1st-31st, 2009. Inclusion criteria were: singleton, term, cephalic, normal fetal heart tracing and no contraindications for epidural. Patients were surveyed regarding their wishes for analgesia, and their reasons for declining epidural. The obstetrics physician performed pain management counseling as is usually done. Patients were asked again about their choice for analgesia. Likert scale questionnaires were used. Wilcoxon signed ranked test was used for categorical variables. Logistic regression was performed to look for predictors of epidural request. Fifty patients were interviewed. Average age was (27.9 ± 6.7), gestational age (39.3 ± 1.3), and a median parity of 2 (range 0-6). 72% declined epidural upon admission, and 61% after counseling (P = 0.14). Most common reasons for declined epidural were 'women should cope with labor pain' (57%), 'fear of back pain' (54%) and 'family/friends advise against epidural' (36%). Acculturation was assessed by years living in the US (10 ± 6.3), preferred language (Spanish 80%) and ethnic self-identification (Hispanic 98%). 38% were high school graduates. In multivariate logistic regression, graduation from high school was the only variable associated to request for epidural in labor (OR 4.94, 95% CI 1.6-15.1). Educational level is associated to requesting an epidural in labor. Knowledge of patients' fears and expectations is essential to develop adequate counseling interventions.
Liu, Jian-Feng; Thorn, David A; Zhang, Yanan; Li, Jun-Xu
2016-07-01
As a modulator of dopaminergic system, trace amine-associated receptor 1 has been shown to play a critical role in regulating the rewarding properties of additive drugs. It has been demonstrated that activation of trace amine-associated receptor 1 decreased the abuse-related behaviors of cocaine in rats. However, the role of trace amine-associated receptor 1 in specific stages of cocaine reward memory is still unclear. Here, using a cocaine-induced conditioned place preference model, we tested the effects of a selective trace amine-associated receptor 1 agonist RO5166017 on the expression, reconsolidation, and extinction of cocaine reward memory. We found that RO5166017 inhibited the expression but not retention of cocaine-induced conditioned place preference. RO5166017 had no effect on the reconsolidation of cocaine reward memory. Pretreatment with RO5166017 before extinction hindered the formation of extinction long-term memory. RO5166017 did not affect the movement during the conditioned place preference test, indicating the inhibitory effect of RO5166017 on the expression of cocaine-induced conditioned place preference was not caused by locomotion inhibition. Using a cocaine i.v. self-administration model, we found that the combined trace amine-associated receptor 1 partial agonist RO5263397 with extinction had no effect on the following cue- and drug-induced reinstatement of cocaine-seeking behavior. Repeated administration of the trace amine-associated receptor 1 agonist during extinction showed a continually inhibitory effect on the expression of cocaine reward memory both in cocaine-induced conditioned place preference and cocaine self-administration models. Taken together, these results indicate that activation of trace amine-associated receptor 1 specifically inhibited the expression of cocaine reward memory. The inhibitory effect of trace amine-associated receptor 1 agonists on cocaine reward memory suggests that trace amine-associated receptor 1 agonists could be a promising agent to prevent cocaine relapse. © The Author 2016. Published by Oxford University Press on behalf of CINP.
Kim, Min-Suk; Min, Hyun-Gi; Lee, Sang-Hwan; Kim, Jeong-Gyu
2016-01-01
Many studies have examined the application of soil amendments, including pH change-induced immobilizers, adsorbents, and organic materials, for soil remediation. This study evaluated the effects of various amendments on trace element stabilization and phytotoxicity, depending on the initial soil pH in acid, neutral, and alkali conditions. As in all types of soils, Fe and Ca were well stabilized on adsorption sites. There was an effect from pH control or adsorption mechanisms on the stabilization of cationic trace elements from inorganic amendments in acidic and neutral soil. Furthermore, acid mine drainage sludge has shown great potential for stabilizing most trace elements. In a phytotoxicity test, the ratio of the bioavailable fraction to the pseudo-total fraction significantly affected the uptake of trace elements by bok choy. While inorganic amendments efficiently decreased the bioavailability of trace elements, significant effects from organic amendments were not noticeable due to the short-term cultivation period. Therefore, the application of organic amendments for stabilizing trace elements in agricultural soil requires further study. PMID:27835687
Kim, Min-Suk; Min, Hyun-Gi; Lee, Sang-Hwan; Kim, Jeong-Gyu
2016-01-01
Many studies have examined the application of soil amendments, including pH change-induced immobilizers, adsorbents, and organic materials, for soil remediation. This study evaluated the effects of various amendments on trace element stabilization and phytotoxicity, depending on the initial soil pH in acid, neutral, and alkali conditions. As in all types of soils, Fe and Ca were well stabilized on adsorption sites. There was an effect from pH control or adsorption mechanisms on the stabilization of cationic trace elements from inorganic amendments in acidic and neutral soil. Furthermore, acid mine drainage sludge has shown great potential for stabilizing most trace elements. In a phytotoxicity test, the ratio of the bioavailable fraction to the pseudo-total fraction significantly affected the uptake of trace elements by bok choy. While inorganic amendments efficiently decreased the bioavailability of trace elements, significant effects from organic amendments were not noticeable due to the short-term cultivation period. Therefore, the application of organic amendments for stabilizing trace elements in agricultural soil requires further study.
AF-GEOSpace Version 2.0: Space Environment Software Products for 2002
NASA Astrophysics Data System (ADS)
Hilmer, R. V.; Ginet, G. P.; Hall, T.; Holeman, E.; Tautz, M.
2002-05-01
AF-GEOSpace Version 2.0 (release 2002 on WindowsNT/2000/XP) is a graphics-intensive software program developed by AFRL with space environment models and applications. It has grown steadily to become a development tool for automated space weather visualization products and helps with a variety of tasks: orbit specification for radiation hazard avoidance; satellite design assessment and post-event analysis; solar disturbance effects forecasting; frequency and antenna management for radar and HF communications; determination of link outage regions for active ionospheric conditions; and physics research and education. The object-oriented C++ code is divided into five module classes. Science Modules control science models to give output data on user-specified grids. Application Modules manipulate these data and provide orbit generation and magnetic field line tracing capabilities. Data Modules read and assist with the analysis of user-generated data sets. Graphics Modules enable the display of features such as plane slices, magnetic field lines, line plots, axes, the Earth, stars, and satellites. Worksheet Modules provide commonly requested coordinate transformations and calendar conversion tools. Common input data archive sets, application modules, and 1-, 2-, and 3-D visualization tools are provided to all models. The code documentation includes detailed examples with click-by-click instructions for investigating phenomena that have well known effects on communications and spacecraft systems. AF-GEOSpace Version 2.0 builds on the success of its predecessors. The first release (Version 1.21, 1996/IRIX on SGI) contained radiation belt particle flux and dose models derived from CRRES satellite data, an aurora model, an ionosphere model, and ionospheric HF ray tracing capabilities. Next (Version 1.4, 1999/IRIX on SGI) science modules were added related to cosmic rays and solar protons, low-Earth orbit radiation dosages, single event effects probability maps, ionospheric scintillation, and shock propagation models. New application modules for estimating linear energy transfer (LET) and single event upset (SEU) rates in solid-state devices, and graphic modules for visualizing radar fans, communication domes, and satellite detector cones and links were added. Automated FTP scripts permitted users to update their global input parameter set directly from NOAA/SEC. What?s New? Version 2.0 includes the first true dynamic run capabilities and offers new and enhanced graphical and data visualization tools such as 3-D volume rendering and eclipse umbra and penumbra determination. Animations of all model results can now be displayed together in all dimensions. There is a new realistic day-to-day ionospheric scintillation simulation generator (IONSCINT), an upgrade to the WBMOD scintillation code, a simplified HF ionospheric ray tracing module, and applications built on the NASA AE-8 and AP-8 radiation belt models. User-generated satellite data sets can now be visualized along with their orbital ephemeris. A prototype tool for visualizing MHD model results stored in structured grids provides a hint of where future space weather model development efforts are headed. A new graphical user interface (GUI) with improved module tracking and renaming features greatly simplifies software operation. AF-GEOSpace is distributed by the Space Weather Center of Excellence in the Space Vehicles Directorate of AFRL. Recently released for WindowsNT/2000/XP, versions for UNIX and LINUX operating systems will follow shortly. To obtain AF-GEOSpace Version 2.0, please send an e-mail request to the first author.
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Wilson, S.A.; Ridley, W.I.; Koenig, A.E.
2002-01-01
The requirements of standard materials for LA-ICP-MS analysis have been difficult to meet for the determination of trace elements in sulfides. We describe a method for the production of synthetic sulfides by precipitation from solution. The method is detailed by the production of approximately 200 g of a material, PS-1, with a suite of chalcophilic trace elements in an Fe-Zn-Cu-S matrix. Preliminary composition data, together with an evaluation of the homogeneity for individual elements, suggests that this type of material meets the requirements for a sulfide calibration standard that allows for quantitative analysis. Contamination of the standard with Na suggests that H2S gas may prove a better sulfur source for future experiments. We recommend that calibration data be collected in whatever mode is closest to that employed for the analysis of the unknown material, because of variable fractionation effects as a function of analytical mode. For instance, if individual spot analyses are attempted on unknown sample, then a raster of several individual spot analyses, not a continuous scan, should be collected and averaged for the standard. Hg and Au are exceptions to the above and calibration data should always be collected in a scanning mode. Au is more heterogeneously distributed than other trace metals and large-area scans are required to provide an average value for calibration purposes. We emphasize that the values given in Table 1 are preliminary values. Further chemical characterization of this standard, through a round-robin analysis program, will allow the USGS to provide both certified and recommended values for individual elements. The USGS has developed PS-1 as a potential new LA-ICP-MS standard for use by the analytical community, and requests for this material should be addressed to S. Wilson. However, it is stressed that an important aspect of the method described here is the flexibility for individual investigators to produce sulfides with a wide range of trace metals in variable matrices. For example, PS-1 is not well suited to the analysis of galena, and it would be relatively straightforward for other standards to be developed with Pb present in the matrix as a major constituent. These standards can be made easily and cheaply in a standard wet chemistry laboratory using equipment and chemicals that are readily available.
Van Hook, R I
1979-01-01
This report addresses the effects of coal-derived trace and radioactive elements. A summary of our current understanding of health and environmental effects of trace and radioactive elements released during coal mining, cleaning, combustion, and ash disposal is presented. Physical and biological transport phenomena which are important in determining organism exposure are also discussed. Biological concentration and transformation as well as synergistic and antagonistic actions among trace contaminants are discussed in terms of their importance in mobility, persistence, availability, and ultimate toxicity. The consequences of implementing the President's National Energy Plan are considered in terms of the impact of the NEP in 1985 and 2000 on the potential effects of trace and radioactive elements from the coal fuel cycle. Areas of needed research are identified in specific recommendations. PMID:540619
Modeling of contact tracing in social networks
NASA Astrophysics Data System (ADS)
Tsimring, Lev S.; Huerta, Ramón
2003-07-01
Spreading of certain infections in complex networks is effectively suppressed by using intelligent strategies for epidemic control. One such standard epidemiological strategy consists in tracing contacts of infected individuals. In this paper, we use a recently introduced generalization of the standard susceptible-infectious-removed stochastic model for epidemics in sparse random networks which incorporates an additional (traced) state. We describe a deterministic mean-field description which yields quantitative agreement with stochastic simulations on random graphs. We also discuss the role of contact tracing in epidemics control in small-world and scale-free networks. Effectiveness of contact tracing grows as the rewiring probability is reduced.
NASA Astrophysics Data System (ADS)
Liang, S. W.; Chang, Y. W.; Chen, Chih
2006-04-01
Three-dimensional thermoelectrical simulation was conducted to investigate the influence of Al-trace dimension on Joule heating and current crowding in flip-chip solder joints. It is found that the dimension of the Al-trace effects significantly on the Joule heating, and thus directly determines the mean time to failure (MTTF). Simulated at a stressing current of 0.6A at 70°C, we estimate that the MTTF of the joints with Al traces in 100μm width was 6.1 times longer than that of joints with Al traces in 34μm width. Lower current crowding effect and reduced hot-spot temperature are responsible for the improved MTTF.
An R package for state-trace analysis.
Prince, Melissa; Hawkins, Guy; Love, Jonathon; Heathcote, Andrew
2012-09-01
State-trace analysis (Bamber, Journal of Mathematical Psychology, 19, 137-181, 1979) is a graphical analysis that can determine whether one or more than one latent variable mediates an apparent dissociation between the effects of two experimental manipulations. State-trace analysis makes only ordinal assumptions and so, is not confounded by range effects that plague alternative methods, especially when performance is measured on a bounded scale (such as accuracy). We describe and illustrate the application of a freely available GUI driven package, StateTrace, for the R language. StateTrace automates many aspects of a state-trace analysis of accuracy and other binary response data, including customizable graphics and the efficient management of computationally intensive Bayesian methods for quantifying evidence about the outcomes of a state-trace experiment, developed by Prince, Brown, and Heathcote (Psychological Methods, 17, 78-99, 2012).
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-15
... fuel or additive, and certain technical, marketing, and health-effects information. The development of... Request; Comment Request; Registration of Fuels and Fuel Additives--Requirements for Manufacturers; EPA... Fuels and Fuel Additives--Requirements for Manufacturers'' (EPA ICR No. 0309.14, OMB Control No. 2060...
Validation of Ray Tracing Code Refraction Effects
NASA Technical Reports Server (NTRS)
Heath, Stephanie L.; McAninch, Gerry L.; Smith, Charles D.; Conner, David A.
2008-01-01
NASA's current predictive capabilities using the ray tracing program (RTP) are validated using helicopter noise data taken at Eglin Air Force Base in 2007. By including refractive propagation effects due to wind and temperature, the ray tracing code is able to explain large variations in the data observed during the flight test.
Context-sensitive trace inlining for Java.
Häubl, Christian; Wimmer, Christian; Mössenböck, Hanspeter
2013-12-01
Method inlining is one of the most important optimizations in method-based just-in-time (JIT) compilers. It widens the compilation scope and therefore allows optimizing multiple methods as a whole, which increases the performance. However, if method inlining is used too frequently, the compilation time increases and too much machine code is generated. This has negative effects on the performance. Trace-based JIT compilers only compile frequently executed paths, so-called traces, instead of whole methods. This may result in faster compilation, less generated machine code, and better optimized machine code. In the previous work, we implemented a trace recording infrastructure and a trace-based compiler for [Formula: see text], by modifying the Java HotSpot VM. Based on this work, we evaluate the effect of trace inlining on the performance and the amount of generated machine code. Trace inlining has several major advantages when compared to method inlining. First, trace inlining is more selective than method inlining, because only frequently executed paths are inlined. Second, the recorded traces may capture information about virtual calls, which simplify inlining. A third advantage is that trace information is context sensitive so that different method parts can be inlined depending on the specific call site. These advantages allow more aggressive inlining while the amount of generated machine code is still reasonable. We evaluate several inlining heuristics on the benchmark suites DaCapo 9.12 Bach, SPECjbb2005, and SPECjvm2008 and show that our trace-based compiler achieves an up to 51% higher peak performance than the method-based Java HotSpot client compiler. Furthermore, we show that the large compilation scope of our trace-based compiler has a positive effect on other compiler optimizations such as constant folding or null check elimination.
Xiu, Junshan; Dong, Lili; Qin, Hua; Liu, Yunyan; Yu, Jin
2016-12-01
The detection limit of trace metals in liquids has been improved greatly by laser-induced breakdown spectroscopy (LIBS) using solid substrate. A paper substrate and a metallic substrate were used as a solid substrate for the detection of trace metals in aqueous solutions and viscous liquids (lubricating oils) respectively. The matrix effect on quantitative analysis of trace metals in two types of liquids was investigated. For trace metals in aqueous solutions using paper substrate, the calibration curves established for pure solutions and mixed solutions samples presented large variation on both the slope and the intercept for the Cu, Cd, and Cr. The matrix effects among the different elements in mixed solutions were observed. However, good agreement was obtained between the measured and known values in real wastewater. For trace metals in lubricating oils, the matrix effect between the different oils is relatively small and reasonably negligible under the conditions of our experiment. A universal calibration curve can be established for trace metals in different types of oils. The two approaches are verified that it is possible to develop a feasible and sensitive method with accuracy results for rapid detection of trace metals in industrial wastewater and viscous liquids by laser-induced breakdown spectroscopy. © The Author(s) 2016.
42 CFR 498.71 - Notice and effect of dismissal and right to request review.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 5 2010-10-01 2010-10-01 false Notice and effect of dismissal and right to request... HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION APPEALS PROCEDURES FOR DETERMINATIONS... and right to request review. (a) Notice of the ALJ's dismissal action is mailed to the parties. The...
Olu, Olushayo Oluseun; Lamunu, Margaret; Nanyunja, Miriam; Dafae, Foday; Samba, Thomas; Sempiira, Noah; Kuti-George, Fredson; Abebe, Fikru Zeleke; Sensasi, Benjamin; Chimbaru, Alexander; Ganda, Louisa; Gausi, Khoti; Gilroy, Sonia; Mugume, James
2016-01-01
Contact tracing is a critical strategy required for timely prevention and control of Ebola virus disease (EVD) outbreaks. Available evidence suggests that poor contact tracing was a driver of the EVD outbreak in West Africa, including Sierra Leone. In this article, we answered the question as to whether EVD contact tracing, as practiced in Western Area (WA) districts of Sierra Leone from 2014 to 2015, was effective. The goal is to describe contact tracing and identify obstacles to its effective implementation. Mixed methods comprising secondary data analysis of the EVD case and contact tracing data sets collected from WA during the period from 2014 to 2015, key informant interviews of contact tracers and their supervisors, and a review of available reports on contact tracing were implemented to obtain data for this study. During the study period, 3,838 confirmed cases and 32,706 contacts were listed in the viral hemorrhagic fever and contact databases for the district (mean 8.5 contacts per case). Only 22.1% (852) of the confirmed cases in the study area were listed as contacts at the onset of their illness, which indicates incomplete identification and tracing of contacts. Challenges associated with effective contact tracing included lack of community trust, concealing of exposure information, political interference with recruitment of tracers, inadequate training of contact tracers, and incomplete EVD case and contact database. While the tracers noted the usefulness of community quarantine in facilitating their work, they also reported delayed or irregular supply of basic needs, such as food and water, which created resistance from the communities. Multiple gaps in contact tracing attributed to a variety of factors associated with implementers, and communities were identified as obstacles that impeded timely control of the EVD outbreak in the WA of Sierra Leone. In future outbreaks, early community engagement and participation in contact tracing, establishment of appropriate mechanisms for selection, adequate training and supervision of qualified contact tracers, establishment of a well-managed and complete contact tracing database, and provision of basic needs to quarantined contacts are recommended as measures to enhance effective contact tracing.
TCP Packet Trace Analysis. M.S. Thesis
NASA Technical Reports Server (NTRS)
Shepard, Timothy J.
1991-01-01
Examination of a trace of packets collected from the network is often the only method available for diagnosing protocol performance problems in computer networks. This thesis explores the use of packet traces to diagnose performance problems of the transport protocol TCP. Unfortunately, manual examination of these traces can be so tedious that effective analysis is not possible. The primary contribution of this thesis is a graphical method of displaying the packet trace which greatly reduce, the tediousness of examining a packet trace. The graphical method is demonstrated by the examination of some packet traces of typical TCP connections. The performance of two different implementations of TCP sending data across a particular network path is compared. Traces many thousands of packets long are used to demonstrate how effectively the graphical method simplifies examination of long complicated traces. In the comparison of the two TCP implementations, the burstiness of the TCP transmitter appeared to be related to the achieved throughput. A method of quantifying this burstiness is presented and its possible relevance to understanding the performance of TCP is discussed.
Selenium, Vanadium, and Chromium as Micronutrients to Improve Metabolic Syndrome.
Panchal, Sunil K; Wanyonyi, Stephen; Brown, Lindsay
2017-03-01
Trace metals play an important role in the proper functioning of carbohydrate and lipid metabolism. Some of the trace metals are thus essential for maintaining homeostasis, while deficiency of these trace metals can cause disorders with metabolic and physiological imbalances. This article concentrates on three trace metals (selenium, vanadium, and chromium) that may play crucial roles in controlling blood glucose concentrations possibly through their insulin-mimetic effects. For these trace metals, the level of evidence available for their health effects as supplements is weak. Thus, their potential is not fully exploited for the target of metabolic syndrome, a constellation that increases the risk for cardiovascular disease and type 2 diabetes. Given that the prevalence of metabolic syndrome is increasing throughout the world, a simpler option of interventions with food supplemented with well-studied trace metals could serve as an answer to this problem. The oxidation state and coordination chemistry play crucial roles in defining the responses to these trace metals, so further research is warranted to understand fully their metabolic and cardiovascular effects in human metabolic syndrome.
Meillère, Alizée; Brischoux, François; Bustamante, Paco; Michaud, Bruno; Parenteau, Charline; Marciau, Coline; Angelier, Frédéric
2016-10-01
In a rapidly urbanizing world, trace element pollution may represent a threat to human health and wildlife, and it is therefore crucial to assess both exposition levels and associated effects of trace element contamination on urban vertebrates. In this study, we investigated the impact of urbanization on trace element contamination and stress physiology in a wild bird species, the common blackbird (Turdus merula), along an urbanization gradient (from rural to moderately urbanized areas). Specifically, we described the contamination levels of blackbirds by 4 non-essential (Ag, Cd, Hg, Pb) and 9 essential trace elements (As, Co, Cr, Cu, Fe, Mn, Ni, Se, Zn), and explored the putative disrupting effects of the non-essential element contamination on corticosterone levels (a hormonal proxy for environmental challenges). We found that non-essential trace element burden (Cd and Pb specifically) increased with increasing urbanization, indicating a significant trace element contamination even in medium sized cities and suburban areas. Interestingly, the increased feather non-essential trace element concentrations were also associated with elevated feather corticosterone levels, suggesting that urbanization probably constrains birds and that this effect may be mediated by trace element contamination. Future experimental studies are now required to disentangle the influence of multiple urban-related constraints on corticosterone levels and to specifically test the influence of each of these trace elements on corticosterone secretion. Copyright © 2016 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Taguchi, Naoko; Kim, Youjin
2016-01-01
This study examined the effects of collaborative dialogue in learning the speech act of request. Seventy-four second-grade girls' junior high students were divided into three groups. The "collaborative group" (n = 25) received explicit metapragmatic information on request (request head act and modifications) followed by a dialogue…
ERIC Educational Resources Information Center
Muthusamy, Paramasivam; Farashaiyan, Atieh
2016-01-01
The present study attempted to describe the request, apology, and request mitigation strategies utilized by international postgraduate students in confronting different situations. In addition, it examined the effects of the situational factors of social distance, power, and imposition on the students' choice of request and apology strategies as…
Washington State Community College Operating Budget, 1985-87. Management Summary.
ERIC Educational Resources Information Center
Washington State Board for Community Coll. Education, Olympia.
A summary is presented of the 1985-87 community college operating budget request for the Washington State Community colleges, along with a description of the policy considerations inherent in the request and the anticipated effect of the request on community college programs. The philosophy and objectives underpinning the budget request are…
NASA Astrophysics Data System (ADS)
Ekwurzel, B.; Frumhoff, P. C.; Allen, M. R.; Boneham, J.; Heede, R.; Dalton, M. W.; Licker, R.
2017-12-01
Given the progress in climate change attribution research over the last decade, attribution studies can inform policymakers guided by the UNFCCC principle of "common but differentiated responsibilities." Historically this has primarily focused on nations, yet requests for information on the relative role of the fossil energy sector are growing. We present an approach that relies on annual CH4 and CO2 emissions from production through to the sale of products from the largest industrial fossil fuel and cement production company records from the mid-nineteenth century to present (Heede 2014). Analysis of the global trends with all the natural and human drivers compared with a scenario without the emissions traced to major carbon producers over full historical versus select periods of recent history can be policy relevant. This approach can be applied with simple climate models and earth system models depending on the type of climate impacts being investigated. For example, results from a simple climate model, using best estimate parameters and emissions traced to 90 largest carbon producers, illustrate the relative difference in global mean surface temperature increase over 1880-2010 after removing these emissions from 1980-2010 (29-35%) compared with removing these emissions over 1880-2010 (42-50%). The changing relative contributions from the largest climate drivers can be important to help assess the changing risks for stakeholders adapting to and reducing exposure and vulnerability to regional climate change impacts.
Trivedi, Mehul A; Coover, Gary D
2006-04-03
Pavlovian delay conditioning, in which a conditioned stimulus (CS) and unconditioned stimulus (US) co-terminate, is thought to reflect non-declarative memory. In contrast, trace conditioning, in which the CS and US are temporally separate, is thought to reflect declarative memory. Hippocampal lesions impair acquisition and expression of trace conditioning measured by the conditioned freezing and eyeblink responses, while having little effect on the acquisition of delay conditioning. Recent evidence suggests that lesions of the ventral hippocampus (VH) impair conditioned fear under conditions in which dorsal hippocampal (DH) lesions have little effect. In the present study, we examined the time-course of fear expression after delay and trace conditioning using the fear-potentiated startle (FPS) reflex, and the effects of pre- and post-training lesions to the VH and DH on trace-conditioned FPS. We found that both delay- and trace-conditioned rats displayed significant FPS near the end of the CS relative to the unpaired control group. In contrast, trace-conditioned rats displayed significant FPS throughout the duration of the trace interval, whereas FPS decayed rapidly to baseline after CS offset in delay-conditioned rats. In experiment 2, both DH and VH lesions were found to significantly reduce the overall magnitude of FPS compared to the control group, however, no differences were found between the DH and VH groups. These findings support a role for both the DH and VH in trace fear conditioning, and suggest that the greater effect of VH lesions on conditioned fear might be specific to certain measures of fear.
Hunt, Pamela S.; Barnet, Robert C.
2015-01-01
Experience-produced deficits in trace conditioning and context conditioning have been useful tools for examining the role of the hippocampus in learning. It has also been suggested that learning in these tasks is especially vulnerable to neurotoxic effects of alcohol during key developmental periods such as adolescence. In five experiments we systematically examined the presence and source of age-dependent vulnerability to the memory-disrupting effects of acute ethanol in trace conditioning and contextual fear conditioning. In Experiment 1a pre-training ethanol disrupted trace conditioning more strongly in adolescent (postnatal day, PD30-35) than adult rats (PD65-75). In Experiment 1b when pre-training ethanol was accompanied by pre-test ethanol no deficit in trace conditioning was observed in adolescents, suggesting that state-dependent retrieval failure mediated ethanol's disruption of trace conditioning at this age. Experiments 2a and 2b examined the effect of ethanol pretreatment on context conditioning. Here, adult but not adolescent rats were impaired in conditioned freezing to context cues. Experiment 2c explored state-dependency of this effect. Pre-training ethanol continued to disrupt context conditioning in adults even when ethanol was also administered prior to test. Collectively these findings reveal clear age-dependent and task-dependent vulnerabilities in ethanol's disruptive effects on hippocampus-dependent memory. Adolescents were more disrupted by ethanol in trace conditioning than adults, and adults were more disrupted by ethanol in context conditioning than adolescents. We suggest that adolescents may be more susceptible to changes in internal state (state-dependent retrieval failure) than adults and that ethanol disrupted performance in trace and context conditioning through different mechanisms. Relevance of these findings to theories of hippocampus function is discussed. PMID:26192910
THE EFFECT OF THE "EVOKING FREEDOM" TECHNIQUE ON AN UNUSUAL AND DISTURBING REQUEST.
Guéguen, Nicolas; Silone, Fabien; David, Mathieu; Pascual, Alexandre
2015-06-01
The "evoking freedom" technique consists in soliciting someone to comply with a request by simply saying that she is free to accept or to refuse the request. However, previous studies used low cost requests. The present study examined the magnitude of this technique associated with a more disturbing and costly request. Sixty men and 60 women aged approximately 20-25 years walking in the street were asked by a male confederate to hold a closed transparent box containing a live trap-door spider while he went into the post office to pick up a package. In the evoking freedom condition, the confederate added in his request that the participant was "free to accept or to refuse." More compliance occurred in the "evoking freedom" condition (53.3%) than in the control condition (36.7%). These results confirm the robustness and the magnitude of the evoking freedom technique on compliance and show that this technique remained effective even when the request was psychologically costly to perform and was associated with fear.
20 CFR 408.814 - Can you request termination of your SVB entitlement?
Code of Federal Regulations, 2013 CFR
2013-04-01
... CERTAIN WORLD WAR II VETERANS Suspensions and Terminations Termination § 408.814 Can you request.... When a termination request is filed, your SVB entitlement ends effective with the month following the...
20 CFR 408.814 - Can you request termination of your SVB entitlement?
Code of Federal Regulations, 2010 CFR
2010-04-01
... CERTAIN WORLD WAR II VETERANS Suspensions and Terminations Termination § 408.814 Can you request.... When a termination request is filed, your SVB entitlement ends effective with the month following the...
20 CFR 408.814 - Can you request termination of your SVB entitlement?
Code of Federal Regulations, 2011 CFR
2011-04-01
... CERTAIN WORLD WAR II VETERANS Suspensions and Terminations Termination § 408.814 Can you request.... When a termination request is filed, your SVB entitlement ends effective with the month following the...
20 CFR 408.814 - Can you request termination of your SVB entitlement?
Code of Federal Regulations, 2014 CFR
2014-04-01
... CERTAIN WORLD WAR II VETERANS Suspensions and Terminations Termination § 408.814 Can you request.... When a termination request is filed, your SVB entitlement ends effective with the month following the...
20 CFR 408.814 - Can you request termination of your SVB entitlement?
Code of Federal Regulations, 2012 CFR
2012-04-01
... CERTAIN WORLD WAR II VETERANS Suspensions and Terminations Termination § 408.814 Can you request.... When a termination request is filed, your SVB entitlement ends effective with the month following the...
Enhanced analgesic effects of tramadol and common trace element coadministration in mice.
Alexa, Teodora; Marza, Aurelia; Voloseniuc, Tudor; Tamba, Bogdan
2015-10-01
Chronic pain is managed mostly by the daily administration of analgesics. Tramadol is one of the most commonly used drugs, marketed in combination with coanalgesics for enhanced effect. Trace elements are frequent ingredients in dietary supplements and may enhance tramadol's analgesic effect either through synergic mechanisms or through analgesic effects of their own. Swiss Weber male mice were divided into nine groups and were treated with a combination of the trace elements Mg, Mn, and Zn in three different doses and a fixed dose of tramadol. Two groups served as positive (tramadol alone) and negative (saline) controls. Nociceptive assessment by tail-flick (TF) and hot-plate (HP) tests was performed at baseline and at 15, 30, 45, and 60 min after intraperitoneal administration. Response latencies were recorded and compared with the aid of ANOVA testing. All three trace elements enhanced tramadol's analgesic effect, as assessed by TF and HP test latencies. Coadministration of these trace elements led to an increase of approximately 30% in the average pain inhibition compared with the tramadol-alone group. The most effective doses were 0.6 mg/kg b.w. for Zn, 75 mg/kg b.w. for Mg, and 7.2 mg/kg b.w. for Mn. Associating trace elements such as Zn, Mg, and Mn with the standard administration of tramadol increases the drug's analgesic effect, most likely a consequence of their synergic action. These findings impact current analgesic treatment because the addition of these trace elements may reduce the tramadol dose required to obtain analgesia. © 2015 Wiley Periodicals, Inc.
Developing L2 Pragmatic Competence in Mandarin Chinese: Sequential Realization of Requests
ERIC Educational Resources Information Center
Su, Yunwen; Ren, Wei
2017-01-01
The present study explored the development of second language (L2) Chinese learners' ability to negotiate requests in interactions. It investigated the effect of proficiency on learners' use of request strategies and internal modifications and on their sequential realization of requests in L2 Chinese. Twenty-four American English learners of L2…
Kravitz, Richard L.; Epstein, Ronald; Feldman, Mitchell D.; Franz, Carol E.; Azari, Rahman; Wilkes, Michael S.; Hinton, Ladson; Franks, Peter
2011-01-01
Context Direct-to-consumer (DTC) advertising of prescription drugs in the United States is both ubiquitous and controversial. Critics charge that DTC advertising leads to over-prescribing, while proponents counter that it helps avert under-use of effective treatments, especially for conditions such as depression that are poorly recognized or stigmatized. Objective To ascertain the effects of patients’ DTC-related requests on physicians’ initial treatment decisions (prescribing, referral, and follow-up) in patients with depressive symptoms. Design Randomized trial using Standardized Patients (SPs). Six SP roles (experimental cells) were created by crossing two conditions (major depression or adjustment disorder) with three request types (brand-specific, general, or none). Setting Offices of primary care physicians in Sacramento, CA; San Francisco, CA; and Rochester, NY. Participants 152 family physicians and general internists recruited from solo and group practices and health maintenance organizations; cooperation rates ranged from 53% to 61%. Interventions SPs were randomly assigned to make 298 unannounced visits, with assignments constrained so physicians saw 1 SP with major depression and 1 with adjustment disorder (approximately 50 visits per experimental cell). Main Outcome Measures Data on prescribing, mental health referral, and primary care follow-up were obtained from SP written reports, visit audio-recordings, chart review, and analysis of written prescriptions and drug samples. The effects of request type on prescribing were evaluated using contingency tables and confirmed in generalized linear mixed models that accounted for clustering and adjusted for site, physician, and visit characteristics. Results SP role fidelity was excellent, and the detection rate was 12%. In major depression, rates of antidepressant prescribing were 53%, 76%, and 31% for SPs making brand-specific requests, general requests, and no requests, respectively (p<.0001). In adjustment disorder, antidepressant prescribing was 55%, 39%, and 10%, respectively (p<.0001). The results were confirmed in multivariate models. “Minimally acceptable initial care” (any combination of an antidepressant, mental health referral, or follow-up within two weeks) in the major depression role was offered to 98% of SPs making a general request, 90% of those making a brand-specific request, and 56% of those making no request (p<0.001). Conclusions Patients’ requests have a profound effect on physician prescribing in major depression and adjustment disorder. DTC advertising may have competing effects on quality, potentially both averting under-use and promoting over-use. PMID:15855433
Co-digestion of manure and industrial waste--The effects of trace element addition.
Nordell, Erik; Nilsson, Britt; Nilsson Påledal, Sören; Karisalmi, Kaisa; Moestedt, Jan
2016-01-01
Manure is one of the most common substrates for biogas production. Manure from dairy- and swine animals are often considered to stabilize the biogas process by contributing nutrients and trace elements needed for the biogas process. In this study two lab-scale reactors were used to evaluate the effects of trace element addition during co-digestion of manure from swine- and dairy animals with industrial waste. The substrate used contained high background concentrations of both cobalt and nickel, which are considered to be the most important trace elements. In the reactor receiving additional trace elements, the volatile fatty acids (VFA) concentration was 89% lower than in the control reactor. The lower VFA concentration contributed to a more digested digestate, and thus lower methane emissions in the subsequent storage. Also, the biogas production rate increased with 24% and the biogas production yield with 10%, both as a result of the additional trace elements at high organic loading rates. All in all, even though 50% of the feedstock consisted of manure, trace element addition resulted in multiple positive effects and a more reliable process with stable and high yield. Copyright © 2015 Elsevier Ltd. All rights reserved.
A Global Overview of Exposure Levels and Biological Effects of Trace Elements in Penguins.
Espejo, Winfred; Celis, José E; GonzÃlez-Acuña, Daniel; Banegas, Andiranel; Barra, Ricardo; Chiang, Gustavo
2018-01-01
Trace elements are chemical contaminants that can be present almost anywhere on the planet. The study of trace elements in biotic matrices is a topic of great relevance for the implications that it can have on wildlife and human health. Penguins are very useful, since they live exclusively in the Southern Hemisphere and represent about 90% of the biomass of birds of the Southern Ocean. The levels of trace elements (dry weight) in different biotic matrices of penguins were reviewed here. Maps of trace element records in penguins were included. Data on exposure and effects of trace elements in penguins were collected from the literature. The most reported trace elements in penguins are aluminum, arsenic, cadmium, lead, mercury, copper, zinc, and manganese. Trace elements have been measured in 11 of the 18 species of penguins. The most studied biotic matrices are feathers and excreta. Most of the studies have been performed in Antarctica and subantarctic Islands. Little is known about the interaction among metals, which could provide better knowledge about certain mechanisms of detoxification in penguins. Future studies of trace elements in penguins must incorporate other metals such as vanadium, cobalt, nickel, and chromium. Data of metals in the species such as Eudyptes pachyrhynchus, Eudyptes moseleyi, Eudyptes sclateri, Eudyptes robustus, Eudyptes schlegeli, Spheniscus demersus, Spheniscus mendiculus, and Megadyptes antipodes are urged. It is important to correlate levels of metals in different biotic matrices with the effects on different species and in different geographic locations.
Helioviewer.org: Browsing Very Large Image Archives Online Using JPEG 2000
NASA Astrophysics Data System (ADS)
Hughitt, V. K.; Ireland, J.; Mueller, D.; Dimitoglou, G.; Garcia Ortiz, J.; Schmidt, L.; Wamsler, B.; Beck, J.; Alexanderian, A.; Fleck, B.
2009-12-01
As the amount of solar data available to scientists continues to increase at faster and faster rates, it is important that there exist simple tools for navigating this data quickly with a minimal amount of effort. By combining heterogeneous solar physics datatypes such as full-disk images and coronagraphs, along with feature and event information, Helioviewer offers a simple and intuitive way to browse multiple datasets simultaneously. Images are stored in a repository using the JPEG 2000 format and tiled dynamically upon a client's request. By tiling images and serving only the portions of the image requested, it is possible for the client to work with very large images without having to fetch all of the data at once. In addition to a focus on intercommunication with other virtual observatories and browsers (VSO, HEK, etc), Helioviewer will offer a number of externally-available application programming interfaces (APIs) to enable easy third party use, adoption and extension. Recent efforts have resulted in increased performance, dynamic movie generation, and improved support for mobile web browsers. Future functionality will include: support for additional data-sources including RHESSI, SDO, STEREO, and TRACE, a navigable timeline of recorded solar events, social annotation, and basic client-side image processing.
42 CFR 405.952 - Withdrawal or dismissal of a request for a redetermination.
Code of Federal Regulations, 2010 CFR
2010-10-01
... to file the redetermination request within the proper filing time frame in accordance with § 405.942... dismissal. (e) Effect of dismissal. The dismissal of a request for redetermination is binding unless it is...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-20
... request a predecisional enforcement conference or request alternative dispute resolution (ADR) with the... the absence of any request for hearing or ADR, or written approval of an extension of time in which to... hearing or ADR is requested, the effective date of this Order shall be determined in accordance with the...
ERIC Educational Resources Information Center
Pitts, Laura; Dymond, Simon
2012-01-01
Research on the high-probability (high-p) request sequence shows that compliance with low-probability (low-p) requests generally increases when preceded by a series of high-p requests. Few studies have conducted formal preference assessments to identify the consequences used for compliance, which may partly explain treatment failures, and still…
Watching AGN feedback at its birth: HST observations of nascent outflow host IC860
NASA Astrophysics Data System (ADS)
Alatalo, Katherine
2016-10-01
IC860 is a nearby IR-luminous early-type spiral with a unique set of properties: it is a shocked, poststarburst galaxy that hosts an AGN-driven neutral wind and a compact core of molecular gas. IC860 can serve as a rosetta stone for the early stages of triggering AGN feedback. We propose to use WFC3 on HST to obtain NUV, optical and near-IR imaging of IC860. We will create a spatially-resolved history of star formation quenching through SED-fitting of 7 requested broadband filters, and compare the spatially resolved star formation histories to in different positions within the underlying stellar features (such as spiral structure) that might define a narrative of how star formation is quenching in IC860. These observations will also resolve the super-star cluster sites to trace the most recent star formation. Finally, these observations will trace the mass of the outflow by building an absorption map of the dust. IC860 presents a unique opportunity to study a galaxy at an early stage of transitioning from blue spiral to red early-type galaxy, that also hosts an AGN-driven neutral wind and a compact, turbulent molecular gas core.
Trace Gases, CO2, Climate, and the Greenhouse Effect.
ERIC Educational Resources Information Center
Aubrecht, Gordon J., II
1988-01-01
Reports carbon dioxide and other trace gases can be the cause of the Greenhouse Effect. Discusses some effects of the temperature change and suggests some solutions. Included are several diagrams, graphs, and a table. (YP)
Outlines of a multiple trace theory of temporal preparation.
Los, Sander A; Kruijne, Wouter; Meeter, Martijn
2014-01-01
We outline a new multiple trace theory of temporal preparation (MTP), which accounts for behavior in reaction time (RT) tasks in which the participant is presented with a warning stimulus (S1) followed by a target stimulus (S2) that requires a speeded response. The theory assumes that during the foreperiod (FP; the S1-S2 interval) inhibition is applied to prevent premature response, while a wave of activation occurs upon the presentation of S2. On each trial, these actions are stored in a separate memory trace, which, jointly with earlier formed memory traces, starts contributing to preparation on subsequent trials. We show that MTP accounts for classic effects in temporal preparation, including mean RT-FP functions observed under a variety of FP distributions and asymmetric sequential effects. We discuss the advantages of MTP over other accounts of these effects (trace-conditioning and hazard-based explanations) and suggest a critical experiment to empirically distinguish among them.
Singer, Alexander; Duarte Fernandez, Roberto
2015-10-28
The Electronic Medical Record (EMR) is becoming increasingly common in health care settings. Research shows that EMRs have the potential to reduce instances of medication errors and improve communication between pharmacists and prescribers; however, more research is required to demonstrate whether this is true. This study aims to determine the effect of a newly implemented EMR system on communication between pharmacists and primary care clinicians. A retrospective chart analysis of primary care EMR data comparing faxed pharmacy communications captured before and after the implementation of an EMR system at an academic family medicine clinic. Communication requests were classified into the following various categories: refill accepted, refill denied, clarification, incorrect dose, interaction, drug insurance/coverage application, new prescription request, supplies request, continued care information, duplicate fax substitution, opioid early release request, confirmation by phone call, and other. The number and percentage of clarification requests, interaction notifications, and incorrect dose notifications were lower after the implementation of the EMR system. The number and percentage of refills accepted and new prescription requests increased after the implementation of the EMR system. The implementation of an EMR in an academic family medicine clinic had a significant effect on the volume of communication between pharmacists and prescribers. The amount of clarification requests and incorrect dosing communications decreased after EMR implementation. This suggests that EMRs improve prescribing safety. The increased amount of refills accepted and new prescription requests post EMR implementation suggests that the EMR is capable of changing prescription patterns.
Lippi, Giuseppe; Brambilla, Marco; Bonelli, Patrizia; Aloe, Rosalia; Balestrino, Antonio; Nardelli, Anna; Ceda, Gian Paolo; Fabi, Massimo
2015-11-01
There is consolidated evidence that the burden of inappropriate laboratory test requests is very high, up to 70%. We describe here the function of a computerized alert system linked to the order entry, designed to limit the number of potentially inappropriate laboratory test requests. A computerized alert system based on re-testing intervals and entailing the generation of pop-up alerts when preset criteria of appropriateness for 15 laboratory tests were violated was implemented in two clinical wards of the University Hospital of Parma. The effectiveness of the system for limiting potentially inappropriate tests was monitored for 6months. Overall, 765/3539 (22%) test requests violated the preset criteria of appropriateness and generated the appearance of electronic alert. After alert appearance, 591 requests were annulled (17% of total tests requested and 77% of tests alerted, respectively). The total number of test requests violating the preset criteria of inappropriateness constantly decreased over time (26% in the first three months of implementation versus 17% in the following period; p<0.001). The total financial saving of test withdrawn was 3387 Euros (12.8% of the total test cost) throughout the study period. The results of this study suggest that a computerized alert system may be effective to limit the inappropriateness of laboratory test requests, generating significant economic saving and educating physicians to a more efficient use of laboratory resources. Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Stevens, Reed; Hall, Rogers
1997-01-01
Reports on an exploratory study of how people see and explain a prominent exhibit (Tornado) at an interactive science museum (the Exploratorium). Data was assembled using a novel, technically mediated activity system (Video Traces). Argues that Video Traces is an effective tool and discusses an expanded Video Traces system. (Author/DKM)
77 FR 24718 - Scientific Information Request on Chronic Venous Ulcers Treatments
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-25
... Venous Ulcers: A Comparative Effectiveness Review of Treatment Modalities report, which is currently... improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review pursuant to Section 1013 of the Medicare...
NASA Technical Reports Server (NTRS)
Hicks, Karen Campbell
2015-01-01
This thesis investigated the communication and decision making process as part of the Systems Engineering practices at the NASA/Marshall Center to determine its level of effectiveness. Data was collected across three change requests to assess how decisions were made, how the decisions were communicated, and whether a process mattered in the formulation and dissemination of those decisions. Data results revealed the comprehensive decision making process for the technical change requests to be effective. Evidence revealed that the process was sufficiently tailored to accommodate the need of each individual technical change which promoted effective communication amongst the stakeholders in the formulation of the strategic decision recommendations elevated to upper management. However, data results also revealed the dissemination of the final decision and approval of the change requests from the higher organizational level down to all stakeholders was less effective. An establishment of a culmination meeting at the end of the change request decision process in which to close the communication loop with all entities would be beneficial.
Sessitsch, Angela; Kuffner, Melanie; Kidd, Petra; Vangronsveld, Jaco; Wenzel, Walter W.; Fallmann, Katharina; Puschenreiter, Markus
2013-01-01
Phytoextraction makes use of trace element-accumulating plants that concentrate the pollutants in their tissues. Pollutants can be then removed by harvesting plants. The success of phytoextraction depends on trace element availability to the roots and the ability of the plant to intercept, take up, and accumulate trace elements in shoots. Current phytoextraction practises either employ hyperaccumulators or fast-growing high biomass plants; the phytoextraction process may be enhanced by soil amendments that increase trace element availability in the soil. This review will focus on the role of plant-associated bacteria to enhance trace element availability in the rhizosphere. We report on the kind of bacteria typically found in association with trace element – tolerating or – accumulating plants and discuss how they can contribute to improve trace element uptake by plants and thus the efficiency and rate of phytoextraction. This enhanced trace element uptake can be attributed to a microbial modification of the absorptive properties of the roots such as increasing the root length and surface area and numbers of root hairs, or by increasing the plant availability of trace elements in the rhizosphere and the subsequent translocation to shoots via beneficial effects on plant growth, trace element complexation and alleviation of phytotoxicity. An analysis of data from literature shows that effects of bacterial inoculation on phytoextraction efficiency are currently inconsistent. Some key processes in plant–bacteria interactions and colonization by inoculated strains still need to be unravelled more in detail to allow full-scale application of bacteria assisted phytoremediation of trace element contaminated soils. PMID:23645938
Sessitsch, Angela; Kuffner, Melanie; Kidd, Petra; Vangronsveld, Jaco; Wenzel, Walter W; Fallmann, Katharina; Puschenreiter, Markus
2013-05-01
Phytoextraction makes use of trace element-accumulating plants that concentrate the pollutants in their tissues. Pollutants can be then removed by harvesting plants. The success of phytoextraction depends on trace element availability to the roots and the ability of the plant to intercept, take up, and accumulate trace elements in shoots. Current phytoextraction practises either employ hyperaccumulators or fast-growing high biomass plants; the phytoextraction process may be enhanced by soil amendments that increase trace element availability in the soil. This review will focus on the role of plant-associated bacteria to enhance trace element availability in the rhizosphere. We report on the kind of bacteria typically found in association with trace element - tolerating or - accumulating plants and discuss how they can contribute to improve trace element uptake by plants and thus the efficiency and rate of phytoextraction. This enhanced trace element uptake can be attributed to a microbial modification of the absorptive properties of the roots such as increasing the root length and surface area and numbers of root hairs, or by increasing the plant availability of trace elements in the rhizosphere and the subsequent translocation to shoots via beneficial effects on plant growth, trace element complexation and alleviation of phytotoxicity. An analysis of data from literature shows that effects of bacterial inoculation on phytoextraction efficiency are currently inconsistent. Some key processes in plant-bacteria interactions and colonization by inoculated strains still need to be unravelled more in detail to allow full-scale application of bacteria assisted phytoremediation of trace element contaminated soils.
78 FR 6362 - Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-30
... prescribed for use by registered investment companies in certain circumstances to request orders of the Commission declaring that the registration of that investment company cease to be in effect. The form requests information about: (i) The investment company's identity, (ii) the investment company's...
76 FR 77834 - Scientific Information Request on Intravascular Diagnostic and Imaging Medical Devices
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-14
... solicited to inform our Comparative Effectiveness Review of Intravascular Diagnostic Procedures and Imaging... scientific information on this device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review...
76 FR 74789 - Scientific Information Request on Pressure Ulcer Treatment Medical Devices
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-01
... Strategies: A Comparative Effectiveness Review, which is currently being conducted by the Evidence-based... scientific information on these devices will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-23
... Comparative Effectiveness of Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special... device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review pursuant to Section 1013 of the...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-24
... is being solicited to inform our Comparative Effectiveness Review of Treatment Strategies for... scientific information on this device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-24
... being solicited to inform our Comparative Effectiveness Review of Local Therapies for Unresectable... scientific information on this device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-26
... is being solicited to inform our Comparative Effectiveness Review of Biologic and Nonbiologic... comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review pursuant to Section 1013 of the Medicare Prescription Drug, Improvement, and...
Uccello-Barretta, Gloria; Balzano, Federica; Aiello, Federica; Falugiani, Niccolò; Desideri, Ielizza
2015-03-25
In total parenteral nutrition (TPN), especially in the case of preterm infants, simultaneous administration of vitamins and trace elements is still a problematic issue: guidelines put in evidence the lack of specific documentation. In this work NMR spectroscopy was applied to the study of vitamins (pyridoxine hydrochloride, thiamine nitrate, riboflavin-5'-phosphate and nicotinamide) stability in presence of salts and trace elements. Vitamins in D2O were first analyzed by (1)H NMR spectroscopy in absence of salts and trace elements; changes in chemical shifts or in diffusion coefficients, measured by NMR DOSY technique, were analyzed. The effects of salts and trace elements on single vitamins and on their admixtures were then investigated by performing quantitative analyses during 48h. Selected vitamins are subject to intermolecular interactions. No degradative effects were observed in presence of salts and trace elements. Only riboflavin-5'-phosphate is subject to precipitation in presence of divalent cations; however, at low concentration and in presence of other vitamins this effect was not observed. Solutions analyzed, in the condition of this study, are stable for at least 48h and vitamins and trace elements can be administered together in TPN. Copyright © 2014 Elsevier B.V. All rights reserved.
Toxic effects of trace elements on newborns and their birth outcomes.
Tang, Mengling; Xu, Chenye; Lin, Nan; Yin, Shanshan; Zhang, Yongli; Yu, Xinwei; Liu, Weiping
2016-04-15
Some trace elements are essential for newborns, their deficiency may cause abnormal biological functions, whereas excessive intakes due to environmental contamination may create adverse health effects. This study was conducted to measure the levels of selected trace elements in Chinese fish consumers by assessing their essentiality and toxicity via colostrum intake in newborns, and evaluated the effects of these trace elements on birth outcomes. Trace elements in umbilical cord serum and colostrum of the studied population were relatively high compared with other populations. The geometric means (GM) of estimated daily intake (EDI, mgday(-1)) of the trace elements were in the safe ranges for infant Dietary Reference Intakes (DRIs) recommended by the United States Food and Drug Administration (FDA). When using total dietary intake (TDI, mgkg(-1)bwday(-1)), zinc (Zn) (0.880mgkg(-1)bwday(-1)) and selenium (Se) (6.39×10(-3)mgkg(-1)bwday(-1)) were above the Reference Doses (RfD), set by the United States Environmental Protection Agency (EPA). Multivariable linear regression analyses showed that Se was negatively correlated with birth outcomes. Our findings suggested that overloading of trace elements due to environmental contamination may contribute to negative birth outcomes. Copyright © 2016 Elsevier B.V. All rights reserved.
78 FR 77173 - Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-20
... because they effect transactions in securities futures products. The information obtained from Rule 17a-13... time complying with the rule, given that they do not do a public securities business or do not hold... SECURITIES AND EXCHANGE COMMISSION Proposed Collection; Comment Request Upon Written Request...
75 FR 22637 - Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-29
... the form prescribed for use by registered investment companies in certain circumstances to request orders of the Commission declaring that the registration of that investment company cease to be in effect. The form requests, from investment companies seeking a deregistration order, information about (i) the...
NASA Technical Reports Server (NTRS)
Koczo, Stefan, Jr.
2013-01-01
Safety analyses of the Traffic Aware Strategic Aircrew Requests (TASAR) Electronic Flight Bag (EFB) application are provided to establish its Failure Effects Classification which affects certification and operational approval requirements. TASAR was developed by NASA Langley Research Center to offer flight path improvement opportunities to the pilot during flight for operational benefits (e.g., reduced fuel, flight time). TASAR, using own-ship and network-enabled information concerning the flight and its environment, including weather and Air Traffic Control (ATC) system constraints, provides recommended improvements to the flight trajectory that the pilot can choose to request via Change Requests to ATC for revised clearance. This study reviews the Change Request process of requesting updates to the current clearance, examines the intended function of TASAR, and utilizes two safety assessment methods to establish the Failure Effects Classification of TASAR. Considerable attention has been given in this report to the identification of operational hazards potentially associated with TASAR.
NASA Astrophysics Data System (ADS)
Koo, Cheol Hea; Lee, Hoon Hee; Moon, Sung Tae; Han, Sang Hyuck; Ju, Gwang Hyeok
2013-08-01
In aerospace research and practical development area, increasing the usage of simulation in software development, component design and system operation has been maintained and the increasing speed getting faster. This phenomenon can be found from the easiness of handling of simulation and the powerfulness of the output from the simulation. Simulation brings lots of benefit from the several characteristics of it as following, - easy to handle ; it is never broken or damaged by mistake - never wear out ; it is never getting old - cost effective ; once it is built, it can be distributed over 100 ~ 1000 people GenSim (Generic Simulator) which is developing by KARI and compatible with ESA SMP standard provides such a simulation platform to support flight software validation and mission operation verification. User interface of GenSim is shown in Figure 1 [1,2]. As shown in Figure 1, as most simulation platform typically has, GenSim has GRD (Graphical Display) and AND (Alpha Numeric Display). But frequently more complex and powerful handling of the simulated data is required at the actual system validation for example mission operation. In Figure 2, system simulation result of COMS (Communication, Ocean, and Meteorological Satellite, launched at June 28 2008) is being drawn by Celestia 3D program. In this case, the needed data from Celestia is given by one of the simulation model resident in system simulator through UDP network connection in this case. But the requirement of displaying format, data size, and communication rate is variable so developer has to manage the connection protocol manually at each time and each case. It brings a chaos in the simulation model design and development, also to the performance issue at last. Performance issue is happen when the required data magnitude is higher than the capacity of simulation kernel to process the required data safely. The problem is that the sending data to a visualization tool such as celestia is given by a simulation model not kernel. Because the simulation model has no way to know about the status of simulation kernel load to process simulation events, as the result the simulation model sends the data as frequent as needed. This story may make many potential problems like lack of response, failure of meeting deadline and data integrity problem with the model data during the simulation. SIMSAT and EuroSim gives a warning message if the user request event such as printing log can't be processed as planned or requested. As the consequence the requested event will be delayed or not be able to be processed, and it means that this phenomenon may violate the planned deadline. In most soft real time simulation, this can be neglected and just make a little inconvenience of users. But it shall be noted that if the user request is not managed properly at some critical situation, the simulation results may be ended with a mess and chaos. As we traced the disadvantages of what simulation model provide the user request, simulation model is not appropriate to provide a service for such user request. This kind of work shall be minimized as much as possible.
Appearance (ethnic origin) of requester affects the foot-in-the-door technique.
Fointiat, Valerie; Saint-Bauzel, Roxane
2010-12-01
A study was designed to examine the effect of the appearance of the requester within one of the variants of the foot-in-the-door paradigm, that is, the foot-in-the-door with implicit demand described by Uranowitz in 1975. A confederate (Black vs. Blanc vs. Beur2) approached the participant in a park and presented a small request. Three steps further, the confederate "accidentally" dropped 30 sheets of paper. Whether or not the participant helped the confederate in retrieving the dropped pamphlets was recorded as the implicit dependent variable. The foot-in-the-door effect was observed solely when the requester was Blanc. This result shows that the foot-in-the-door effect is not as strong as the literature suggests and undermines the usual interpretations of the foot-in-the-door effect in terms of self-perception and commitment.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-26
... solicited to inform our Comparative Effectiveness Review of Local Therapies for Unresectable Primary... device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review pursuant to Section 1013 of the...
77 FR 24716 - Scientific Information Request on Medical Devices To Treat Otitis Media With Effusion
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-25
... devices. Scientific information is being solicited to inform our Comparative Effectiveness Review of... scientific information on this device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review...
Development Of Knowledge Systems For Trouble Shooting Complex Production Machinery
NASA Astrophysics Data System (ADS)
Sanford, Richard L.; Novak, Thomas; Meigs, James R.
1987-05-01
This paper discusses the use of knowledge base system software for microcomputers to aid repairmen in diagnosing electrical failures in complex mining machinery. The knowledge base is constructed to allow the user to input initial symptoms of the failed machine, and the most probable cause of failure is traced through the knowledge base, with the software requesting additional information such as voltage or resistance measurements as needed. Although the case study presented is for an underground mining machine, results have application to any industry using complex machinery. Two commercial expert-system development tools (M1 TM and Insight 2+TM) and an Al language (Turbo PrologTM) are discussed with emphasis on ease of application and suitability for this study.
Dynamic Polymorphic Reconfiguration to Effectively Cloak a Circuit’s Function
2011-03-24
86 B . RSA Traces . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89 2.1...56 22 SEMA of Separate Square and Multiply Trace with key (E B5) - RSA Version B ...56 23 Separate Square and Multiply Trace after signal processing - RSA Version B
Climate-chemical interactions and effects of changing atmospheric trace gases
NASA Technical Reports Server (NTRS)
Ramanathan, V.; Callis, L.; Cess, R.; Hansen, J.; Isaksen, I.
1987-01-01
The paper considers trace gas-climate effects including the greenhouse effect of polyatomic trace gases, the nature of the radiative-chemical interactions, and radiative-dynamical interactions in the stratosphere, and the role of these effects in governing stratospheric climate change. Special consideration is given to recent developments in the investigations of the role of oceans in governing the transient climate responses, and a time-dependent estimate of the potential trace gas warming from the preindustrial era to the early 21st century. The importance of interacting modeling and observational efforts is emphasized. One of the problems remaining on the observational front is the lack of certainty in current estimates of the rate of growth of CO, O3, and NOx; the primary challenge is the design of a strategy that will minimize the sampling errors.
77 FR 17406 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-26
... surveys distributed to determine the impact on national security. Affected Public: Businesses and other...: Bureau of Industry and Security. Title: Request for Investigation Under Section 232 of the Trade.... Needs and Uses: Upon request, BIS will initiate an investigation to determine the effects of imports of...
Comparing FDTD and Ray-Tracing Models in Numerical Simulation of HgCdTe LWIR Photodetectors
NASA Astrophysics Data System (ADS)
Vallone, Marco; Goano, Michele; Bertazzi, Francesco; Ghione, Giovanni; Schirmacher, Wilhelm; Hanna, Stefan; Figgemeier, Heinrich
2016-09-01
We present a simulation study of HgCdTe-based long-wavelength infrared detectors, focusing on methodological comparisons between the finite-difference time-domain (FDTD) and ray-tracing optical models. We performed three-dimensional simulations to determine the absorbed photon density distributions and the corresponding photocurrent and quantum efficiency spectra of isolated n-on- p uniform-composition pixels, systematically comparing the results obtained with FDTD and ray tracing. Since ray tracing is a classical optics approach, unable to describe interference effects, its applicability has been found to be strongly wavelength dependent, especially when reflections from metallic layers are relevant. Interesting cavity effects around the material cutoff wavelength are described, and the cases where ray tracing can be considered a viable approximation are discussed.
Murray, Elizabeth; Lo, Bernard; Pollack, Lance; Donelan, Karen; Lee, Ken
2004-01-01
To determine public perceptions of the effect of direct-to-consumer advertising (DTCA) of prescription medications on health behaviors, health care utilization, the doctor-patient relationship, and the association between socioeconomic status and these effects. Cross-sectional survey of randomly selected, nationally representative sample of the US public using computer-assisted telephone interviewing. numbers and proportions of respondents in the past 12 months who, as a result of DTCA, requested preventive care or scheduled a physician visit; were diagnosed with condition mentioned in advertisement; disclosed health concerns to a doctor; felt enhanced confidence or sense of control; perceived an effect on the doctor-patient relationship; requested a test, medication change, or specialist referral; or manifested serious dissatisfaction after a visit to a doctor. As a result of DTCA, 14% of respondents disclosed health concerns to a physician, 6% requested preventive care, 5% felt more in control during a physician visit; 5% made requests for a test, medication change, or specialist referral, and 3% received the requested intervention. One percent of patients reported negative outcomes, including worsened treatment, serious dissatisfaction with the visit, or that the physician acted challenged. Effects of DTCA were greater for respondents with low socioeconomic status. DTCA has positive and negative effects on health behaviors, health service utilization, and the doctor-patient relationship that are greatest on people of low socioeconomic status. The benefits of DTCA in terms of encouraging hard-to-reach sections of the population to seek preventive care must be balanced against increased health care costs caused by clinically inappropriate requests generated by DTCA.
[Effects of asylum seekers on external migration].
Zakee, R
1992-02-01
Data concerning requests for asylum from migrants to the Netherlands are discussed. The author finds an increase from around 1,000 such requests per year in the early 1980s to over 20,000 for 1990 and 1991. It is also noted that, although women and children have a good chance of being granted asylum, most requests are rejected. The effect of this on the number of illegal aliens in the country is examined. (SUMMARY IN ENG)
78 FR 42954 - Scientific Information Request on Imaging Tests for the Staging of Colorectal Cancer
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-18
.... Scientific information is being solicited to inform our Comparative Effectiveness Review of Imaging Tests for... scientific information on these devices will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review...
78 FR 38716 - Scientific Information Request on Imaging Tests for the Staging of Colorectal Cancer
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-27
.... Scientific information is being solicited to inform our Comparative Effectiveness Review of Imaging Tests for... scientific information on these devices will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review...
ERIC Educational Resources Information Center
Lehmann, Constance M.; Heagy, Cynthia D.
2008-01-01
The authors investigated the effects of professional experience and group interaction on the information that information technology professionals and graduate accounting information system (AIS) students request when analyzing business cases related to information systems design and implementation. Understanding these effects can contribute to…
A new method for automated discontinuity trace mapping on rock mass 3D surface model
NASA Astrophysics Data System (ADS)
Li, Xiaojun; Chen, Jianqin; Zhu, Hehua
2016-04-01
This paper presents an automated discontinuity trace mapping method on a 3D surface model of rock mass. Feature points of discontinuity traces are first detected using the Normal Tensor Voting Theory, which is robust to noisy point cloud data. Discontinuity traces are then extracted from feature points in four steps: (1) trace feature point grouping, (2) trace segment growth, (3) trace segment connection, and (4) redundant trace segment removal. A sensitivity analysis is conducted to identify optimal values for the parameters used in the proposed method. The optimal triangular mesh element size is between 5 cm and 6 cm; the angle threshold in the trace segment growth step is between 70° and 90°; the angle threshold in the trace segment connection step is between 50° and 70°, and the distance threshold should be at least 15 times the mean triangular mesh element size. The method is applied to the excavation face trace mapping of a drill-and-blast tunnel. The results show that the proposed discontinuity trace mapping method is fast and effective and could be used as a supplement to traditional direct measurement of discontinuity traces.
5 CFR 1203.12 - Granting or denying the request for regulation review.
Code of Federal Regulations, 2010 CFR
2010-01-01
... ORGANIZATION AND PROCEDURES PROCEDURES FOR REVIEW OF RULES AND REGULATIONS OF THE OFFICE OF PERSONNEL MANAGEMENT Procedures for Review § 1203.12 Granting or denying the request for regulation review. (a) The..., review a regulation before its effective date. (b) After considering the request for regulation review...
31 CFR 306.106 - Requests for suspension of transactions in bearer securities.
Code of Federal Regulations, 2010 CFR
2010-07-01
... bearer securities, or registered securities so assigned as to become in effect payable to bearer, were... transactions in bearer securities. 306.106 Section 306.106 Money and Finance: Treasury Regulations Relating to... GENERAL REGULATIONS GOVERNING U.S. SECURITIES Requests for Suspension of Transactions § 306.106 Requests...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-13
... additive and certain technical, marketing, and health-effects information. The development of health... Submitted to OMB for Review and Approval; Comment Request; Registration of Fuels and Fuel Additives...), Registration of Fuels and Fuel Additives--Requirements for Manufacturers (Renewal) (EPA ICR No. 0309.14, OMB...
5 CFR 841.1006 - Additional provisions.
Code of Federal Regulations, 2010 CFR
2010-01-01
... request or revocation is effective when processed by OPM. OPM will process each request by the first day...) OPM will provide the State with the information necessary to properly process a request for State... will issue an accounting. If the State finds this accounting unacceptable, it may then and only then...
42 CFR 90.4 - Contents of requests for health assessments.
Code of Federal Regulations, 2010 CFR
2010-10-01
... ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES ADMINISTRATIVE... assessment. (c) Each request for a health assessment should include, where possible: (1) Any other... 42 Public Health 1 2010-10-01 2010-10-01 false Contents of requests for health assessments. 90.4...
Use of a tracing task to assess visuomotor performance for evidence of concussion and recuperation.
Kelty-Stephen, Damian G; Qureshi Ahmad, Mona; Stirling, Leia
2015-12-01
The likelihood of suffering a concussion while playing a contact sport ranges from 15-45% per year of play. These rates are highly variable as athletes seldom report concussive symptoms, or do not recognize their symptoms. We performed a prospective cohort study (n = 206, aged 10-17) to examine visuomotor tracing to determine the sensitivity for detecting neuromotor components of concussion. Tracing variability measures were investigated for a mean shift with presentation of concussion-related symptoms and a linear return toward baseline over subsequent return visits. Furthermore, previous research relating brain injury to the dissociation of smooth movements into "submovements" led to the expectation that cumulative micropause duration, a measure of motion continuity, might detect likelihood of injury. Separate linear mixed effects regressions of tracing measures indicated that 4 of the 5 tracing measures captured both short-term effects of injury and longer-term effects of recovery with subsequent visits. Cumulative micropause duration has a positive relationship with likelihood of participants having had a concussion. The present results suggest that future research should evaluate how well the coefficients for the tracing parameter in the logistic regression help to detect concussion in novel cases. (c) 2015 APA, all rights reserved).
Zhang, Wanli; Zhang, Lei; Li, Aimin
2015-11-01
This study aimed at investigating the effects of trace metals on methane production from food waste and examining the feasibility of reducing metals dosage by ethylenediamine-N,N'-disuccinic acid (EDDS) via improving metals bioavailability. The results indicated that the effects of metal elements highly depended on the supplemental concentrations. Trace metals supplemented under moderate concentrations greatly enhanced the methane yield. However, the excessive supplementation of Fe (1000 mg/L) and Ni (50 mg/L) exhibited the obvious toxicity to methanogens. The combinations of trace metals exhibited remarkable synergistic effects. The supplementation of Fe (100 mg/L) + Co (1 mg/L) + Mo (5 mg/L) + Ni (5 mg/L) obtained the greatest methane yield of 504 mL/g VSadded and the highest increment of 35.5% compared to the reactor without metals supplementation (372 mL/g VSadded). The changes of metals speciation showed the reduction of metals bioavailability during anaerobic digestion, which might weaken the stimulative effects of trace metals. However, the addition of EDDS improved metals bioavailability for microbial uptake and stimulated the activity of methanogens, and therefore, strengthened the stimulative effects of metals on anaerobic digestion of food waste. The batch and semi-continuous experiments confirmed that the addition of EDDS (20 mg/L) bonded to trace metals prior to their supplementation could obtain a 50% reduction of optimal metals dosage. This study provided a feasible method to reduce trace metals dosage without the degeneration of process performance of anaerobic digestion. Copyright © 2015 Elsevier Ltd. All rights reserved.
A trace map comparison algorithm for the discrete fracture network models of rock masses
NASA Astrophysics Data System (ADS)
Han, Shuai; Wang, Gang; Li, Mingchao
2018-06-01
Discrete fracture networks (DFN) are widely used to build refined geological models. However, validating whether a refined model can match to reality is a crucial problem, concerning whether the model can be used for analysis. The current validation methods include numerical validation and graphical validation. However, the graphical validation, aiming at estimating the similarity between a simulated trace map and the real trace map by visual observation, is subjective. In this paper, an algorithm for the graphical validation of DFN is set up. Four main indicators, including total gray, gray grade curve, characteristic direction and gray density distribution curve, are presented to assess the similarity between two trace maps. A modified Radon transform and loop cosine similarity are presented based on Radon transform and cosine similarity respectively. Besides, how to use Bézier curve to reduce the edge effect is described. Finally, a case study shows that the new algorithm can effectively distinguish which simulated trace map is more similar to the real trace map.
Investigation of ecosystems impacts from geothermal development in Imperial Valley, California
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shinn, J.H.; Ireland, R.R.; Kercher, J.R.
1979-07-13
A summary of three years of field ecological investigation in Imperial Valley Environmental Program is presented. The potential terrestrial habitat impacts of geothermal development are discussed for shorebirds and waterfowl habitat, the endangered clapper rail, powerline corridors, noise effects, animal trace element burdens, and the desert community. Aquatic habitats are discussed in terms of Salton Sea salinity, effects of geothermal brine discharges to the Salton Sea, trace element baselines, and potential toxicity of brine spills in freshwater. Studies of impacts on agriculture involved brine movement in soil, release of trace metals, trace element baselines in soil and plants, water requirementsmore » of crops, and H{sub 2}S effects on crop production in the presence of CO{sub 2} and ozone.« less
Use of portable X-ray fluorescence spectroscopy and geostatistics for health risk assessment.
Yang, Meng; Wang, Cheng; Yang, Zhao-Ping; Yan, Nan; Li, Feng-Ying; Diao, Yi-Wei; Chen, Min-Dong; Li, Hui-Ming; Wang, Jin-Hua; Qian, Xin
2018-05-30
Laboratory analysis of trace metals using inductively coupled plasma (ICP) spectroscopy is not cost effective, and the complex spatial distribution of soil trace metals makes their spatial analysis and prediction problematic. Thus, for the health risk assessment of exposure to trace metals in soils, portable X-ray fluorescence (PXRF) spectroscopy was used to replace ICP spectroscopy for metal analysis, and robust geostatistical methods were used to identify spatial outliers in trace metal concentrations and to map trace metal distributions. A case study was carried out around an industrial area in Nanjing, China. The results showed that PXRF spectroscopy provided results for trace metal (Cu, Ni, Pb and Zn) levels comparable to ICP spectroscopy. The results of the health risk assessment showed that Ni posed a higher non-carcinogenic risk than Cu, Pb and Zn, indicating a higher priority of concern than the other elements. Sampling locations associated with adverse health effects were identified as 'hotspots', and high-risk areas were delineated from risk maps. These 'hotspots' and high-risk areas were in close proximity to and downwind from petrochemical plants, indicating the dominant role of industrial activities as the major sources of trace metals in soils. The approach used in this study could be adopted as a cost-effective methodology for screening 'hotspots' and priority areas of concern for cost-efficient health risk management. Copyright © 2018 Elsevier Inc. All rights reserved.
Trace elements in agroecosystems and impacts on the environment.
He, Zhenli L; Yang, Xiaoe E; Stoffella, Peter J
2005-01-01
Trace elements mean elements present at low concentrations (mg kg-1 or less) in agroecosystems. Some trace elements, including copper (Cu), zinc (Zn), manganese (Mn), iron (Fe), molybdenum (Mo), and boron (B) are essential to plant growth and are called micronutrients. Except for B, these elements are also heavy metals, and are toxic to plants at high concentrations. Some trace elements, such as cobalt (Co) and selenium (Se), are not essential to plant growth but are required by animals and human beings. Other trace elements such as cadmium (Cd), lead (Pb), chromium (Cr), nickel (Ni), mercury (Hg), and arsenic (As) have toxic effects on living organisms and are often considered as contaminants. Trace elements in an agroecosystem are either inherited from soil parent materials or inputs through human activities. Soil contamination with heavy metals and toxic elements due to parent materials or point sources often occurs in a limited area and is easy to identify. Repeated use of metal-enriched chemicals, fertilizers, and organic amendments such as sewage sludge as well as wastewater may cause contamination at a large scale. A good example is the increased concentration of Cu and Zn in soils under long-term production of citrus and other fruit crops. Many chemical processes are involved in the transformation of trace elements in soils, but precipitation-dissolution, adsorption-desorption, and complexation are the most important processes controlling bioavailability and mobility of trace elements in soils. Both deficiency and toxicity of trace elements occur in agroecosystems. Application of trace elements in fertilizers is effective in correcting micronutrient deficiencies for crop production, whereas remediation of soils contaminated with metals is still costly and difficult although phytoremediation appears promising as a cost-effective approach. Soil microorganisms are the first living organisms subjected to the impacts of metal contamination. Being responsive and sensitive, changes in microbial biomass, activity, and community structure as a result of increased metal concentration in soil may be used as indicators of soil contamination or soil environmental quality. Future research needs to focus on the balance of trace elements in an agroecosystem, elaboration of soil chemical and biochemical parameters that can be used to diagnose soil contamination with or deficiency in trace elements, and quantification of trace metal transport from an agroecosystem to the environment.
76 FR 77833 - Scientific Information Request on CYP2C19 Variants and Platelet Reactivity Tests
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-14
... inform our Comparative Effectiveness Review of Testing of CYP2C19 Variants and Platelet Reactivity for... information on this device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative effectiveness review pursuant to...
Classification of conductance traces with recurrent neural networks
NASA Astrophysics Data System (ADS)
Lauritzen, Kasper P.; Magyarkuti, András; Balogh, Zoltán; Halbritter, András; Solomon, Gemma C.
2018-02-01
We present a new automated method for structural classification of the traces obtained in break junction experiments. Using recurrent neural networks trained on the traces of minimal cross-sectional area in molecular dynamics simulations, we successfully separate the traces into two classes: point contact or nanowire. This is done without any assumptions about the expected features of each class. The trained neural network is applied to experimental break junction conductance traces, and it separates the classes as well as the previously used experimental methods. The effect of using partial conductance traces is explored, and we show that the method performs equally well using full or partial traces (as long as the trace just prior to breaking is included). When only the initial part of the trace is included, the results are still better than random chance. Finally, we show that the neural network classification method can be used to classify experimental conductance traces without using simulated results for training, but instead training the network on a few representative experimental traces. This offers a tool to recognize some characteristic motifs of the traces, which can be hard to find by simple data selection algorithms.
The effect of pasteurization on trace elements in donor breast milk.
Mohd-Taufek, N; Cartwright, D; Davies, M; Hewavitharana, A K; Koorts, P; McConachy, H; Shaw, P N; Sumner, R; Whitfield, K
2016-10-01
Premature infants often receive pasteurized donor human milk when mothers are unable to provide their own milk. This study aims to establish the effect of the pasteurization process on a range of trace elements in donor milk. Breast milk was collected from 16 mothers donating to the milk bank at the Royal Brisbane and Women's Hospital. Samples were divided into pre- and post-pasteurization aliquots and were Holder pasteurized. Inductively coupled plasma mass spectrometry was used to analyze the trace elements zinc (Zn), copper (Cu), selenium (Se), manganese (Mn), iodine (I), iron (Fe), molybdenum (Mo) and bromine (Br). Differences in trace elements pre- and post-pasteurization were analyzed. No significant differences were found between the trace elements tested pre- and post-pasteurization, except for Fe (P<0.05). The median (interquartile range, 25 to 75%; μg l(-1)) of trace elements for pre- and post- pasteurization aliquots were-Zn: 1639 (888-4508), 1743 (878-4143), Cu: 360 (258-571), 367 (253-531), Se: 12.34 (11.73-17.60), 12.62 (11.94-16.64), Mn: (1.48 (1.01-1.75), 1.49 (1.11-1.75), I (153 (94-189), 158 (93-183), Fe (211 (171-277), 194 (153-253), Mo (1.46 (0.37-2.99), 1.42 (0.29-3.73) and Br (1066 (834-1443), 989 (902-1396). Pasteurization had minimal effect on several trace elements in donor breast milk but high levels of inter-donor variability of trace elements were observed. The observed decrease in the iron content of pasteurized donor milk is, however, unlikely to be clinically relevant.
76 FR 10366 - Agency Information Collection Request; 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-24
...). Abstract: This research leverages best practices in behavior change, interaction design, and service innovation to increase the understanding and adoption of Comparative Effectiveness Research (CER) information..., translation, and adoption of evidence-based, outcomes- oriented CER findings. Comparative Effectiveness...
77 FR 11121 - Scientific Information Request on Treatment of Atrial Fibrillation
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-24
... fibrillation medical devices. Scientific information is being solicited to inform our Comparative Effectiveness... unpublished pertinent scientific information on this device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative...
76 FR 10367 - Agency Information Collection Request; 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-24
.... Proposed Project: Research Evaluation and Impact Assessment of ARRA Comparative Effectiveness Research... under real-world conditions in diverse populations and clinical practice settings, that is, comparative... Coordinating Council on Comparative Effectiveness Research (FCCCER) to help coordinate and minimize duplicative...
Instruction and Pragmatic Change during Study Abroad Email Communication
ERIC Educational Resources Information Center
Alcón-Soler, Eva
2015-01-01
The study deals with the effect of instruction and study abroad (SA) on pragmatic knowledge. More specifically, the focus is on gains in explicit knowledge of request mitigators, and whether learners draw on this knowledge when they perform email requests. Email requests produced by 60 Spanish students staying abroad (30 treatment/30 control…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-13
... DEPARTMENT OF LABOR Proposed Information Collection Request of the ETA 204, Experience Rating.... Background: The data submitted annually on the ETA-204 report enables the Employment and Training... systems. Used in conjunction with other data, the ETA-204 assists in determining the effects of certain...
78 FR 14791 - Public Water System Supervision Program Approval for the State of Indiana
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-07
... Management (IDEM) has revised several of its rules to comply with the National Primary Drinking Water... motion, this determination shall become final and effective on April 8, 2013. Any request for a public..., organization, or other entity requesting a hearing; a brief statement of the requesting person's interest in...
39 CFR 3001.72 - Filing of formal requests.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Requests for Changes in the Nature of Postal Services § 3001.72 Filing of formal requests. Whenever the... in the nature of postal services subject to this subpart, the Postal Service shall file with the... Postal Service proposes to make effective the change in the nature of postal services involved. Within 5...
Olieman, Renske M; Siemonsma, Femke; Bartens, Margaux A; Garthus-Niegel, Susan; Scheele, Fedde; Honig, Adriaan
2017-06-19
Obstetricians are often reluctant to grant requests for an elective cesarean section (ECS) due to childbirth fear. To date, it is unknown if an ECS on request improves mental well-being in the mother in the peripartum period and if possible beneficial effects on anxiety and depression could outweigh the increased risk of complications associated with a surgical delivery. A systematic review was conducted to explore the effect of ECS on request on peripartum anxiety and depression. We searched on PubMed, PsychoInfo and Embase. Studies were included with primary data on anxiety and/or depression postpartum in women with childbirth fear who had requested an ECS. After full-text evaluation of 65 papers and quality analysis of four papers, three papers were included. Of one paper additional and yet unpublished data were provided. Studies varied in outcome measures, hence no meta-analysis was performed. Women who requested an ECS had higher antepartum depression and anxiety levels but no different postpartum depression levels than women who delivered vaginally. One study of good quality examined the effect of vaginal delivery in women preferring ECS: These women had significantly higher symptom levels of post-traumatic stress disorder (PTSD) and depression than women with normal vaginal delivery. The prospect of an ECS does not lower antepartum anxiety and/or depression levels in women requesting an ECS. If women resolutely persist in wishing an ECS despite adequate counselling and/or psychiatric treatment, the risk of developing depressive and PTSD symptoms in case of vaginal delivery should be taken into account, and an ECS may be considered as a valid alternative.
Epidural analgesia during labour, routinely or on request: a cost-effectiveness analysis.
Bonouvrié, Kimberley; van den Bosch, Anouk; Roumen, Frans J M E; van Kuijk, Sander M; Nijhuis, Jan G; Evers, Silvia M A A; Wassen, Martine M L H
2016-12-01
To assess the cost-effectiveness of routine labour epidural analgesia (EA), from a societal perspective, as compared with labour analgesia on request. Women delivering of a singleton in cephalic presentation beyond 36+0 weeks' gestation were randomly allocated to routine labour EA or analgesia on request in one university and one non-university teaching hospital in the Netherlands. Costs included all medical, non-medical and indirect costs from randomisation to 6 weeks postpartum. Effectiveness was defined as a non-operative, spontaneous vaginal delivery without EA-related maternal adverse effects. Incremental cost-effectiveness ratio (ICER) was defined as the ratio of the difference in costs and the difference in effectiveness between both groups. Data were analysed according to intention to treat and divided into a base case analysis and a sensitivity analysis. Total delivery costs in the routine EA group (n=233) were higher than in the labour on request group (n=255) (difference -€ 322, 95% CI -€ 60 to € 355) due to more medication costs (including EA), a longer stay in the labour ward, and more operations including caesarean sections. Total postpartum hospital costs in the routine EA group were lower (difference -€ 344, 95% CI -€ 1338 to € 621) mainly due to less neonatal admissions (difference -€ 472, 95% CI -€ 1297 to € 331), whereas total postpartum home and others costs were comparable (difference -€ 20, 95% CI -€ 267 to € 248, and -€ 1, 95% CI -€ 67 to € 284, respectively). As a result, the overall mean costs per woman were comparable between the routine EA group and the analgesia on request group (€ 8.708 and € 8.710, respectively, mean difference -€ 2, 95% CI -€ 1.012 to € 916). Routine labour EA resulted in more deliveries with maternal adverse effects, nevertheless the ICER remained low (€ 8; bootstrap 95% CI -€ 6.120 to € 8.659). The cost-effectiveness acceptability curve indicated a low probability that routine EA is cost-effective. Routine labour EA generates comparable costs as analgesia on request, but results in more operative deliveries and more EA-related maternal adverse effects. Based on cost-effectiveness, no preference can be given to routine labour EA as compared with analgesia on request. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Neural Affective Mechanisms Predict Market-Level Microlending
Genevsky, Alexander; Knutson, Brian
2015-01-01
Humans sometimes share with others whom they may never meet or know, in violation of the dictates of pure self-interest. Research has not established which neuropsychological mechanisms support lending decisions, nor whether their influence extends to markets involving significant financial incentives. In two studies, we found that neural affective mechanisms influence the success of requests for microloans. In a large Internet database of microloan requests (N = 13,500), we found that positive affective features of photographs promoted the success of those requests. We then established that neural activity (i.e., in the nucleus accumbens) and self-reported positive arousal in a neuroimaging sample (N = 28) predicted the success of loan requests on the Internet, above and beyond the effects of the neuroimaging sample’s own choices (i.e., to lend or not). These findings suggest that elicitation of positive arousal can promote the success of loan requests, both in the laboratory and on the Internet. They also highlight affective neuroscience’s potential to probe neuropsychological mechanisms that drive microlending, enhance the effectiveness of loan requests, and forecast market-level behavior. PMID:26187248
Pezze, M A; Marshall, H J; Cassaday, H J
2016-08-01
In an appetitively motivated procedure, we have previously reported that systemic treatment with the dopamine (DA) D1 receptor agonist SKF81297 (0.4 and 0.8 mg/kg) depressed acquisition at a 2 s inter-stimulus-interval (ISI), suitable to detect trace conditioning impairment. However since DA is involved in reinforcement processes, the generality of effects across appetitively- and aversively-motivated trace conditioning procedures cannot be assumed. The present study tested the effects of SKF81297 (0.4 and 0.8 mg/kg) in an established conditioned emotional response (CER) procedure. Trace-dependent conditioning was clearly shown in two experiments: while conditioning was relatively strong at a 3-s ISI, it was attenuated at a 30-s ISI. This was shown after two (Experiment 1) or four (Experiment 2) conditioning trials conducted in - as far as possible - the same CER procedure. Contrary to prediction, in neither experiment was there any indication that trace conditioning was attenuated by treatment with 0.4 or 0.8 mg/kg SKF81297. In the same rats, locomotor activity was significantly enhanced at the 0.8 mg/kg dose of SKF81297. These results suggest that procedural details of the trace conditioning variant in use are an important determinant of the profile of dopaminergic modulation.
The effect of tissue structure and soil chemistry on trace element uptake in fossils
NASA Astrophysics Data System (ADS)
Hinz, Emily A.; Kohn, Matthew J.
2010-06-01
Trace element profiles for common divalent cations (Sr, Zn, Ba), rare-earth elements (REE), Y, U, and Th were measured in fossil bones and teeth from the c. 25 ka Merrell locality, Montana, USA, by using laser-ablation ICP-MS. Multiple traverses in teeth were transformed into 2-D trace element maps for visualizing structural influences on trace element uptake. Trace element compositions of different soils from the fossil site were also analyzed by solution ICP-MS, employing progressive leaches that included distilled H 2O, 0.1 M acetic acid, and microwave digestion in concentrated HCl-HNO 3. In teeth, trace element uptake in enamel is 2-4 orders of magnitude slower than in dentine, forming an effective trace element barrier. Uptake in dentine parallel to the dentine-enamel interface is enhanced by at least 2 orders of magnitude compared to transverse, causing trace element "plumes" down the tooth core. In bone, U, Ba and Sr are nearly homogeneous, implying diffusivities ˜5 orders of magnitude faster than in enamel and virtually complete equilibration with host soils. In contrast all REE show strong depletions inward, with stepwise linear segments in log-normal or inverse complementary error function plots; these data require a multi-medium diffusion model, with about 2 orders of magnitude difference in slowest vs. fastest diffusivities. Differences in REE diffusivities in bone (slow) vs. dentine (fast) reflect different partition coefficients ( Kd's). Although acid leaches and bulk digestion of soils yield comparable fossil-soil Kd's among different elements, natural solutions are expected to be neutral to slightly basic. Distilled H 2O leachates instead reveal radically different Kd's in bone for REE than for U-Sr-Ba, suggest orders of magnitude lower effective diffusivities for REE, and readily explain steep vs. flat profiles for REE vs. U-Sr-Ba, respectively. Differences among REE Kd's and diffusivities may explain inward changes in Ce anomalies. Acid washes and bulk soil compositions yield misleading Kd's for many trace elements, especially the REE, and H 2O-leaches are preferred. Patterns of trace element distributions indicate diagenetic alteration at all scales, including enamel, and challenge the use of trace elements in paleodietary studies.
Trace-Based Microanalytic Measurement of Self-Regulated Learning Processes
ERIC Educational Resources Information Center
Siadaty, Melody; Gaševic, Dragan; Hatala, Marek
2016-01-01
To keep pace with today's rapidly growing knowledge-driven society, productive self-regulation of one's learning processes are essential. We introduce and discuss a trace-based measurement protocol to measure the effects of scaffolding interventions on self-regulated learning (SRL) processes. It guides tracing of learners' actions in a learning…
76 FR 1616 - Agency Information Collection Request; 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-11
.... Proposed Project: Comparative Effectiveness Research Inventory--OMB No. 0990-New-Assistant Secretary for... directly to a web-based inventory of comparative effectiveness research (CER). The CER Inventory will...: Research, human & scientific capital (e.g., training/education, methods development), data infrastructure...
75 FR 80504 - Agency Information Collection Request. 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-22
.... Proposed Project: Comparative Effectiveness Research Inventory--OMB No. 0990-New-Assistant Secretary for... directly to a web-based inventory of comparative effectiveness research (CER). The CER Inventory will...: research, human & scientific capital (e.g., training/education, methods development), data infrastructure...
Greenhouse effects due to man-made perturbations of trace gases
NASA Technical Reports Server (NTRS)
Wang, W. C.; Yung, Y. L.; Lacis, A. A.; Mo, T.; Hansen, J. E.
1976-01-01
Nitrous oxide, methane, ammonia, and a number of other trace constituents of the earth's atmosphere have infrared absorption bands in the spectral range from 7 to 14 microns. Despite their small amounts, these gases can have a significant effect on the thermal structure of the atmosphere by transmitting most of the thermal radiation from the earth's surface to the lower atmosphere. In the present paper, this greenhouse effect is computed for a number of trace gases. The nature and climatic implications of possible changes in the concentrations of N2O, CH4, NH3, and HNO3 are discussed.
An examination of body tracing among women with high body dissatisfaction.
Williams, Gail A; Hudson, Danae L; Whisenhunt, Brooke L; Crowther, Janis H
2014-09-01
Within eating disorder treatment programs, a body tracing activity is often used to address body dissatisfaction and overestimation of body size; however, the effects of this activity have never been empirically evaluated. This research examined the effects of body tracing on body dissatisfaction and mood among 56 female participants assigned to either a body tracing or control group. Scores were collected on trait body dissatisfaction and a series of Visual Analogue Scales (VAS). Results showed that trait body dissatisfaction moderated the relationship between group and levels of state appearance dissatisfaction and anxiety. These results suggest that individuals experiencing higher levels of trait body dissatisfaction demonstrated greater state body dissatisfaction following participation in the body tracing activity. Individuals with lower trait body dissatisfaction experienced greater anxiety after drawing a human body. These findings have potential implications for the use of this strategy in the treatment of eating disorder patients. Copyright © 2014 Elsevier Ltd. All rights reserved.
42 CFR 423.1064 - Notice and effect of dismissal and right to request review.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 3 2012-10-01 2012-10-01 false Notice and effect of dismissal and right to request review. 423.1064 Section 423.1064 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... BENEFIT Appeal Procedures for Civil Money Penalties § 423.1064 Notice and effect of dismissal and right to...
42 CFR 423.1064 - Notice and effect of dismissal and right to request review.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 3 2014-10-01 2014-10-01 false Notice and effect of dismissal and right to request review. 423.1064 Section 423.1064 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... BENEFIT Appeal Procedures for Civil Money Penalties § 423.1064 Notice and effect of dismissal and right to...
42 CFR 423.1064 - Notice and effect of dismissal and right to request review.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 3 2010-10-01 2010-10-01 false Notice and effect of dismissal and right to request review. 423.1064 Section 423.1064 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... Appeal Procedures for Civil Money Penalties § 423.1064 Notice and effect of dismissal and right to...
42 CFR 423.1064 - Notice and effect of dismissal and right to request review.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 3 2011-10-01 2011-10-01 false Notice and effect of dismissal and right to request review. 423.1064 Section 423.1064 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... Appeal Procedures for Civil Money Penalties § 423.1064 Notice and effect of dismissal and right to...
42 CFR 423.1064 - Notice and effect of dismissal and right to request review.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 42 Public Health 3 2013-10-01 2013-10-01 false Notice and effect of dismissal and right to request review. 423.1064 Section 423.1064 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... BENEFIT Appeal Procedures for Civil Money Penalties § 423.1064 Notice and effect of dismissal and right to...
Spangler, Lawrence E.; Susong, David D.
2006-01-01
At the request of and in cooperation with the Geology Program at Yellowstone National Park, the U.S. Geological Survey conducted a hydrologic investigation of the Sylvan Pass area in June 2005 to determine the relation between surface water and ground-water flow to Mammoth Crystal Springs. Results of a dye-tracing investigation indicate that streamflow lost into talus deposits on Sylvan Pass enters the ground-water system and moves to the southeast to discharge at Mammoth Crystal Springs. Ground-water travel times to the springs from a distance of 1.45 miles and a vertical relief of 500 feet were less than 1 day, indicating apparent rates of movement of at least 8,000 feet per day, values that are similar to those in karst aquifers. Peak dye concentrations were reached about 2 days after dye injection, and transit time of most of the dye mass through the system was about 3 weeks. High permeability and rapid travel times within this aquifer also are indicated by the large variation in springflow in response to snowmelt runoff and precipitation, and by the high concentration of suspended sediment (turbidity) in the water discharging into the spring-fed lake.
Ramírez-Rivera, José; Cruz, Juan; Jaume-Anselmi, Francisco
2006-12-01
Attitudes in regard to end-of life issues are evolving in Western societies. We have sought to trace this evolution in the relatively homogeneous cultural setting of Puerto Rico. One hundred fifty-two medical students, 62 medical residents and 84 members of three medical faculties were asked whether in terminally ill patients they: 1) would support a request for euthanasia(E); 2) if legalized, would engage in, would oppose or would not be opposed to others engaging physician-assisted suicide(PAS); 3) would consider ethical to prescribe full doses of drugs needed to alleviate pain, even if they knew it would hasten death; 4) would agree to limit certain resources for the terminally ill. Gender and religious affiliation were also requested. Twenty-eight percent of the students, 26% of the residents and 31% of the faculty supported E. Only 13% of the students, 18% of the residents and 11% of the faculty would engage in PAS. Men were more willing than women to acquiesce to a request for E or PAS. Religious affiliation or its absence did not influence the support or opposition to E and PAS. If it would hasten death, 86% of the residents, but only 65% of the faculty considered ethical to prescribe the dose of drugs needed to alleviate pain. More than 2/3 of the students, residents and faculty favored the limiting of certain resources for the terminally ill. In our cultural and medical environment, men are more willing than women to engage in E or PAS. The attitude towards E and PAS is not influenced by religious affiliation. If it hastens death, some still consider unethical to prescribe full doses of drugs needed to alleviate pain in the dying patient.
77 FR 20716 - Drawbridge Operation Regulation; Blackwater River, South Quay, VA
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-06
... passage of vessels. There have been no requests for openings in 11 years. DATES: This rule is effective... S189 Bridge across Blackwater River, mile 9.2, at South Quay VA. There has been no request for openings since the year 2000. The only industrial waterway user to request openings left the area in 2000. Since...
A View from CAEL: Are Your Employees Asking for Career Development?
ERIC Educational Resources Information Center
Council for Adult and Experiential Learning, 2013
2013-01-01
The Council for Adult and Experiential Learning (CAEL) created this document in response to an increased amount of requests for effective career development strategies that target the entry and mid-level workforce. These requests came from a number of different industry sectors throughout the country. This paper summarizes all of those requests,…
Parents' Agreement to Purchase Healthy Snack Foods Requested by Their Children
ERIC Educational Resources Information Center
Carson, Diane E.; Reiboldt, Wendy
2010-01-01
Research shows that parents agree to purchase their children's food requests 45% to 65% of the time. This study examined an after-school nutrition education intervention in terms of its effects on parents' agreement to purchase healthy snack foods requested by their children. Survey data from 755 parents were analyzed. Of the 67% of parents asked…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-08
... Arsenic Rule which will provide for better public health protection by lowering the maximum contaminant... interested parties are invited to submit written comments on this determination and may request a public... determination shall become effective on November 8, 2010 if no timely and appropriate request for a hearing is...
Effects of Culture and Gender in Comprehension of Speech Acts of Indirect Request
ERIC Educational Resources Information Center
Shams, Rabe'a; Afghari, Akbar
2011-01-01
This study investigates the comprehension of indirect request speech act used by Iranian people in daily communication. The study is an attempt to find out whether different cultural backgrounds and the gender of the speakers affect the comprehension of the indirect request of speech act. The sample includes thirty males and females in Gachsaran…
Reinforcement, Behavior Constraint, and the Overjustification Effect.
ERIC Educational Resources Information Center
Williams, Bruce W.
1980-01-01
Four levels of the behavior constraint-reinforcement variable were manipulated: attractive reward, unattractive reward, request to perform, and a no-reward control. Only the unattractive reward and request groups showed the performance decrements that suggest the overjustification effect. It is concluded that reinforcement does not cause the…
77 FR 37660 - Withdrawal of Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-22
... of Information on Compliance Costs and Other Effects of Regulations.'' At this time, the Bureau... of Information on Compliance Costs and Other Effects of Regulations.'' Any comments the Bureau has... BUREAU OF CONSUMER FINANCIAL PROTECTION Withdrawal of Submission for OMB Review; Comment Request...
Food product tracing technology capabilities and interoperability.
Bhatt, Tejas; Zhang, Jianrong Janet
2013-12-01
Despite the best efforts of food safety and food defense professionals, contaminated food continues to enter the food supply. It is imperative that contaminated food be removed from the supply chain as quickly as possible to protect public health and stabilize markets. To solve this problem, scores of technology companies purport to have the most effective, economical product tracing system. This study sought to compare and contrast the effectiveness of these systems at analyzing product tracing information to identify the contaminated ingredient and likely source, as well as distribution of the product. It also determined if these systems can work together to better secure the food supply (their interoperability). Institute of Food Technologists (IFT) hypothesized that when technology providers are given a full set of supply-chain data, even for a multi-ingredient product, their systems will generally be able to trace a contaminated product forward and backward through the supply chain. However, when provided with only a portion of supply-chain data, even for a product with a straightforward supply chain, it was expected that interoperability of the systems will be lacking and that there will be difficulty collaborating to identify sources and/or recipients of potentially contaminated product. IFT provided supply-chain data for one complex product to 9 product tracing technology providers, and then compared and contrasted their effectiveness at analyzing product tracing information to identify the contaminated ingredient and likely source, as well as distribution of the product. A vertically integrated foodservice restaurant agreed to work with IFT to secure data from its supply chain for both a multi-ingredient and a simpler product. Potential multi-ingredient products considered included canned tuna, supreme pizza, and beef tacos. IFT ensured that all supply-chain data collected did not include any proprietary information or information that would otherwise identify the supply-chain partner who provided the information prior to sharing this information with product tracing technology providers. The 9 traceability solution providers who agreed to participate in this project have their systems deployed in a wide range of sectors within the food industry including, but not limited to, livestock, dairy, produce, fruits, seafood, meat, and pork; as well as in pharmaceutical, automotive, retail, and other industries. Some have also been implemented across the globe including Canada, China, USA, Norway, and the EU, among others. This broad commercial use ensures that the findings of this work are applicable to a broad spectrum of the food system. Six of the 9 participants successfully completed the data entry phase of this test. To verify successful data entry for these 6, a demo or screenshots of the data set from each system's user interface was requested. Only 4 of the 6 were able to provide us with this evidence for verification. Of the 6 that completed data entry and moved on to the scenarios phase of the test, 5 were able to provide us with the responses to the scenarios. Time metrics were useful for evaluating the scalability and usability of each technology. Scalability was derived from the time it took to enter the nonstandardized data set into the system (ranges from 7 to 11 d). Usability was derived from the time it took to query the scenarios and provide the results (from a few hours to a week). The time was measured in days it took for the participants to respond after we supplied them all the information they would need to successfully execute each test/scenario. Two of the technology solution providers successfully implemented and participated in a proof-of-concept interoperable framework during Year 2 of this study. While not required, they also demonstrated this interoperability capability on the FSMA-mandated food product tracing pilots for the U.S. FDA. This has significant real-world impact since the demonstration of interoperability enables U.S. FDA to obtain evidence on the importance and impact of data-sharing moving forward. Another real-world accomplishment is the modification or upgrade of commercial technology solutions to enhance or implement interoperability. As these systems get deployed by clients in the food industry, interoperability will no longer be an afterthought but will be built into their traceability systems. In turn, industry and regulators will better understand the capabilities of the currently available technologies, and the technology provider community will identify ways in which their systems may be further developed to increase interoperability and utility. © 2013 Institute of Food Technologists®
Evolution of Archival Storage (from Tape to Memory)
NASA Technical Reports Server (NTRS)
Ramapriyan, Hampapuram K.
2015-01-01
Over the last three decades, there has been a significant evolution in storage technologies supporting archival of remote sensing data. This section provides a brief survey of how these technologies have evolved. Three main technologies are considered - tape, hard disk and solid state disk. Their historical evolution is traced, summarizing how reductions in cost have helped being able to store larger volumes of data on faster media. The cost per GB of media is only one of the considerations in determining the best approach to archival storage. Active archives generally require faster response to user requests for data than permanent archives. The archive costs have to consider facilities and other capital costs, operations costs, software licenses, utilities costs, etc. For meeting requirements in any organization, typically a mix of technologies is needed.
De la Salle, Barbara
2017-02-15
The complete blood count (CBC) is one of the most frequently requested tests in laboratory medicine, performed in a range of healthcare situations. The provision of an ideal assay material for external quality assessment is confounded by the fragility of the cellular components of blood, the lack of commutability of stabilised whole blood material and the lack of certified reference materials and methods to which CBC results can be traced. The choice of assay material between fresh blood, extended life assay material and fully stabilised, commercially prepared, whole blood material depends upon the scope and objectives of the EQA scheme. The introduction of new technologies in blood counting and the wider clinical application of parameters from the extended CBC will bring additional challenges for the EQA provider.
Characterizing parallel file-access patterns on a large-scale multiprocessor
NASA Technical Reports Server (NTRS)
Purakayastha, A.; Ellis, Carla; Kotz, David; Nieuwejaar, Nils; Best, Michael L.
1995-01-01
High-performance parallel file systems are needed to satisfy tremendous I/O requirements of parallel scientific applications. The design of such high-performance parallel file systems depends on a comprehensive understanding of the expected workload, but so far there have been very few usage studies of multiprocessor file systems. This paper is part of the CHARISMA project, which intends to fill this void by measuring real file-system workloads on various production parallel machines. In particular, we present results from the CM-5 at the National Center for Supercomputing Applications. Our results are unique because we collect information about nearly every individual I/O request from the mix of jobs running on the machine. Analysis of the traces leads to various recommendations for parallel file-system design.
USDA-ARS?s Scientific Manuscript database
While many studies have examined the effect of microbial infections on the status of trace elements in mammalian tissues, similar studies have not been performed in insects. We used inductively coupled plasma-mass spectrometry (ICP-MS) to quantify changes in trace elements of Mg, Mn, Fe, Cu, Zn and ...
78 FR 54623 - Effects of Foreign Policy-Based Export Controls
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-05
... Foreign Policy-Based Export Controls AGENCY: Bureau of Industry and Security, Commerce. ACTION: Request... export controls in the Export Administration Regulations. BIS is requesting public comments to conduct... with industry on the effect of such controls and to report the results of the consultations to Congress...
NASA Astrophysics Data System (ADS)
Vizzini, S.; Di Leonardo, R.; Costa, V.; Tramati, C. D.; Luzzu, F.; Mazzola, A.
2013-12-01
Research into the effects of ocean acidification on marine ecosystems has increasingly focused on natural CO2 vents, although their intrinsic environmental complexity means observations from these areas may not relate exclusively to pH gradients. In order to assess trace element levels and distribution in the Levante Bay (Vulcano Island, NE Sicily, Italy) and its suitability for studying biological effects of pH decline, Ba, Fe and trace elements (As, Cd, Co, Cr, Cu, Hg, Mn, Mo, Ni, Pb, V and Zn) in sediment were analysed from 7 transects. Where present, Cymodocea nodosa leaves and epiphytes were also analysed. At the spatial scale of the bay, trace element concentrations in sediments and biota showed wide variability, possibly related to both input from fluid emissions and seawater physico-chemical variables (i.e. pH and Eh), which may considerably affect the solubility and bioavailability of potentially harmful trace elements. According to two pollution indices (MSPI: Marine Sediment Pollution Index and SQG-Q: Sediment Quality Guideline Quotient), the bay can be considered to be affected by low contamination with moderate potential for adverse biological effects, especially in the area between about 150 and 350 m from the primary vent, where localized detrimental effects on biota may occur. Generally, biological samples showed concentrations that were comparable with the lower values of seagrass ranges. The overall results of this study support the complex spatial dynamics of trace elements in the CO2 vent studied, which are constrained by both direct input from the vent and/or biogeochemical processes affecting element precipitation at the sediment-seawater interface. Consequently, great caution should be used when relating biological changes along pH gradients to the unifactorial effect of pH only, as interactions with concurrent, multiple stressors, including trace element enrichments, may occur. This finding has implications for the use of CO2 vents as analogues in ocean acidification research. They should be considered more appropriately as analogues for low pH environments with non-negligible trace element contamination which, in a scenario of continuous increase in anthropogenic pollution, may be very common.
Authoring Model-Tracing Cognitive Tutors
ERIC Educational Resources Information Center
Blessing, Stephen B.; Gilbert, Stephen B.; Ourada, Stephen; Ritter, Steven
2009-01-01
Intelligent Tutoring Systems (ITSs) that employ a model-tracing methodology have consistently shown their effectiveness. However, what evidently makes these tutors effective, the cognitive model embedded within them, has traditionally been difficult to create, requiring great expertise and time, both of which come at a cost. Furthermore, an…
Guéguen, Nicolas
2003-04-01
In an attempt to test the door-in-the-face (DITF) technique in a computer-mediated context, 1,607 men and women taken at random in various e-mail lists were solicited to visit a web site for the profit of a humanitarian organization. In DITF condition, subjects were first solicited by an exaggerated request and, after refusing, were solicited for a small donation. In control condition the donation solicitation was formulated directly. In all the cases, the request was manipulated by the order of the successive HTML pages of the site. Results show that the DITF procedure increase compliance to the last request. The theoretical implication of the effect of this technique in a computer-communication context is discussed.
12 CFR Appendix A to Part 1026 - Effect on State Laws
Code of Federal Regulations, 2014 CFR
2014-01-01
... 12 Banks and Banking 9 2014-01-01 2014-01-01 false Effect on State Laws A Appendix A to Part 1026.... A Appendix A to Part 1026—Effect on State Laws Request for Determination A request for a determination that a state law is inconsistent or that a state law is substantially the same as the Act and...
12 CFR Appendix A to Part 226 - Effect on State Laws
Code of Federal Regulations, 2013 CFR
2013-01-01
... 12 Banks and Banking 3 2013-01-01 2013-01-01 false Effect on State Laws A Appendix A to Part 226... (CONTINUED) TRUTH IN LENDING (REGULATION Z) Pt. 226, App. A Appendix A to Part 226—Effect on State Laws Request for Determination A request for a determination that a State law is inconsistent or that a State...
ERIC Educational Resources Information Center
Stefan, Jordy; Jacob, Céline; Guéguen, Nicolas
2015-01-01
Studies have shown that restaurant waitresses with hair ornamentation receive higher tips than waitresses without ornaments. However, the effect of such ornamentation on other behaviors has never been explored. In this study, the effect of a female interviewer's hair ornamentation on compliance with a survey request was examined. Male and female…
1993-02-01
3.1.2. Modeling of Environment ....................... 6 3.1.3. Ray Tracing and Radiosity ..................... 8 3.2. Reflectivity Review...SIG modeling is dependent on proper treatment of its effects. 3.1.3 Ray Tracing and Radiosity Prior to reviewing reflectivity, a brief look is made of...methods of applying complex theoretical energy propagation algorithms. Two such methods are ray tracing and radiosity (Goral, et al, 1984). Ray tracing is a
Both trace and delay conditioned eyeblink responding can be dissociated from outcome expectancy.
Weidemann, Gabrielle; Broderick, Joshua; Lovibond, Peter F; Mitchell, Christopher J
2012-01-01
Squire and colleagues have proposed that trace and delay eyeblink conditioning are fundamentally different kinds of learning: trace conditioning requires acquisition of a conscious declarative memory for the stimulus contingencies whereas delay conditioning does not. Declarative memory in trace conditioning is thought to generate conditioned responding through the activation of a conscious expectancy for when the unconditioned stimulus (US) is going to occur. Perruchet (1985) has previously shown that in a 50% partial reinforcement design it is possible to dissociate single cue delay eyeblink conditioning from conscious expectancy for the US by examining performance over runs of reinforced and nonreinforced trials. Clark, Manns, and Squire (2001) claim that this dissociation does not occur in trace eyeblink conditioning. In the present experiment we examined the Perruchet effect for short, moderate, and long trace intervals (600, 1000, and 1400 ms) and for the equivalent interstimulus intervals (ISIs) in a delay conditioning procedure. We found evidence for a dissociation of eyeblink CRs and US expectancy over runs regardless of whether there was a delay or a trace arrangement of cues. The reasons for the Perruchet effect are still unclear, but the present data suggest that it does not depend on a separate nondeclarative system of the type proposed by Squire and colleagues. (c) 2012 APA, all rights reserved.
Infectious disease control using contact tracing in random and scale-free networks
Kiss, Istvan Z; Green, Darren M; Kao, Rowland R
2005-01-01
Contact tracing aims to identify and isolate individuals that have been in contact with infectious individuals. The efficacy of contact tracing and the hierarchy of traced nodes—nodes with higher degree traced first—is investigated and compared on random and scale-free (SF) networks with the same number of nodes N and average connection K. For values of the transmission rate larger than a threshold, the final epidemic size on SF networks is smaller than that on corresponding random networks. While in random networks new infectious and traced nodes from all classes have similar average degrees, in SF networks the average degree of nodes that are in more advanced stages of the disease is higher at any given time. On SF networks tracing removes possible sources of infection with high average degree. However a higher tracing effort is required to control the epidemic than on corresponding random networks due to the high initial velocity of spread towards the highly connected nodes. An increased latency period fails to significantly improve contact tracing efficacy. Contact tracing has a limited effect if the removal rate of susceptible nodes is relatively high, due to the fast local depletion of susceptible nodes. PMID:16849217
Example-Tracing Tutors: Intelligent Tutor Development for Non-Programmers
ERIC Educational Resources Information Center
Aleven, Vincent; McLaren, Bruce M.; Sewall, Jonathan; van Velsen, Martin; Popescu, Octav; Demi, Sandra; Ringenberg, Michael; Koedinger, Kenneth R.
2016-01-01
In 2009, we reported on a new Intelligent Tutoring Systems (ITS) technology, example-tracing tutors, that can be built without programming using the Cognitive Tutor Authoring Tools (CTAT). Creating example-tracing tutors was shown to be 4-8 times as cost-effective as estimates for ITS development from the literature. Since 2009, CTAT and its…
Analyzing crowdsourced ratings of speech-based take-over requests for automated driving.
Bazilinskyy, P; de Winter, J C F
2017-10-01
Take-over requests in automated driving should fit the urgency of the traffic situation. The robustness of various published research findings on the valuations of speech-based warning messages is unclear. This research aimed to establish how people value speech-based take-over requests as a function of speech rate, background noise, spoken phrase, and speaker's gender and emotional tone. By means of crowdsourcing, 2669 participants from 95 countries listened to a random 10 out of 140 take-over requests, and rated each take-over request on urgency, commandingness, pleasantness, and ease of understanding. Our results replicate several published findings, in particular that an increase in speech rate results in a monotonic increase of perceived urgency. The female voice was easier to understand than a male voice when there was a high level of background noise, a finding that contradicts the literature. Moreover, a take-over request spoken with Indian accent was found to be easier to understand by participants from India than by participants from other countries. Our results replicate effects in the literature regarding speech-based warnings, and shed new light on effects of background noise, gender, and nationality. The results may have implications for the selection of appropriate take-over requests in automated driving. Additionally, our study demonstrates the promise of crowdsourcing for testing human factors and ergonomics theories with large sample sizes. Copyright © 2017 Elsevier Ltd. All rights reserved.
CaLRS: A Critical-Aware Shared LLC Request Scheduling Algorithm on GPGPU
Ma, Jianliang; Meng, Jinglei; Chen, Tianzhou; Wu, Minghui
2015-01-01
Ultra high thread-level parallelism in modern GPUs usually introduces numerous memory requests simultaneously. So there are always plenty of memory requests waiting at each bank of the shared LLC (L2 in this paper) and global memory. For global memory, various schedulers have already been developed to adjust the request sequence. But we find few work has ever focused on the service sequence on the shared LLC. We measured that a big number of GPU applications always queue at LLC bank for services, which provide opportunity to optimize the service order on LLC. Through adjusting the GPU memory request service order, we can improve the schedulability of SM. So we proposed a critical-aware shared LLC request scheduling algorithm (CaLRS) in this paper. The priority representative of memory request is critical for CaLRS. We use the number of memory requests that originate from the same warp but have not been serviced when they arrive at the shared LLC bank to represent the criticality of each warp. Experiments show that the proposed scheme can boost the SM schedulability effectively by promoting the scheduling priority of the memory requests with high criticality and improves the performance of GPU indirectly. PMID:25729772
Oyama, Yoshimasa; Iwasaka, Hideo; Shiihara, Keisuke; Hagiwara, Satoshi; Kubo, Nobuhiro; Fujitomi, Yutaka; Noguchi, Takayuki
2011-10-01
In order to enhance postoperative recovery, preoperative consumption of carbohydrate (CHO) drinks has been used to suppress metabolic fluctuations. Trace elements such as zinc and copper are known to play an important role in postoperative recovery. Here, we examined the effects of preoperatively consuming a CHO drink containing zinc and copper. Subjects were 122 elective surgery patients divided into two groups (overnight fasting and CHO groups); each group was further divided into morning or afternoon surgery groups. Subjects in the CHO group consumed 300 mL of a CHO drink the night before surgery, followed by 200 ml before morning surgery or 700 ml before afternoon surgery (> or =2 hours before anesthesia induction). Blood levels of glucose, nonesterified fatty acids (NEFA), retinol-binding protein, zinc, and copper were determined. One subject in the CHO group was excluded after refusing the drink. There were no adverse effects from the CHO drink. NEFA levels increased in the fasting groups. Although zinc levels increased in the CHO group immediately after anesthesia induction, no group differences were observed the day after surgery. Preoperative consumption of a CHO drink containing trace elements suppressed preoperative metabolic fluctuations without complications and prevented trace element deficiency. Further beneficial effects during the perioperative period can be expected by adding trace elements to CHO supplements.
A simple model for closure temperature of a trace element in cooling bi-mineralic systems
NASA Astrophysics Data System (ADS)
Liang, Yan
2015-09-01
Closure temperature is defined as the lower temperature limit at which the element of interest effectively ceases diffusive exchange with its surrounding medium during cooling. Here we generalize the classic equation of Dodson (1973) for cooling mono-mineralic systems to cooling bi-mineralic aggregates by considering diffusive exchange of a trace element between the two minerals in a closed system. We present a simple analytical model that includes key parameters affecting the closure temperature of a trace element in cooling bi-mineralic systems: cooling rate, temperature-dependent diffusion coefficients for the trace element in the two minerals, temperature-dependent partition coefficient of the trace element between the two minerals, effective grain sizes of the two minerals, and volume proportions of the minerals in the system. We show that closure temperatures of a trace element in cooling bi-mineralic systems are bounded by the closure temperatures of the trace element in the two mono-mineralic systems and that our generalized model reduces to Dodson's equation when one of the mineral serves as "an effective infinite" reservoir to the other mineral. Application to closure temperatures of REE in orthopyroxene and clinopyroxene bi-mineralic systems highlights the importance of REE diffusion and partitioning in the pyroxenes as well as clinopyroxene modal abundance and grain size in the systems. Closure temperatures for REE in two-pyroxene bearing equigranular rocks are controlled primarily by diffusion in orthopyroxene unless the modal abundance of clinopyroxene is very small. This has important bearings on the interpretation of temperatures derived from the REE-in-two-pyroxene thermometer.
77 FR 70444 - Agency Information Collection Activities: Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-26
... Collection Request: New collection; Title: Medicare Plan Finder Experiment; Use: The mission of the Centers... experimental design to assess the effectiveness of two potential enhancements to the Medicare Plan Finder tool... experiment is to test the effects of two prospective enhancements to the Medicare Plan Finder (MPF) Web site...
A home tracing program for contacts of people with tuberculosis or HIV and patients lost to care.
Deery, C B; Hanrahan, C F; Selibas, K; Bassett, J; Sanne, I; Van Rie, A
2014-05-01
Primary care clinic serving a high tuberculosis (TB) and human immunodeficiency virus (HIV) prevalence community in South Africa. To evaluate a program combining TB and HIV contact investigation with tracing of individuals lost to TB or HIV care. Contacts were offered home-based HIV testing, TB symptom screening, sputum collection and referral for isoniazid preventive therapy (IPT). Effectiveness was assessed by the number needed to trace (NNT). Only 419/1197 (35.0%) households were successfully traced. Among 267 contacts, we diagnosed 27 new HIV cases (10 linked to care) and two TB cases (both initiated treatment) and three started IPT. Of 630 patients lost to care, 132 (21.0%) were successfully traced and 81 (61.4%) re-engaged in care. The NNT to locate one individual lost to care was 4.8 (95%CI 4.1-5.6), to re-engage one person in care 7.8 (95%CI 6.4-9.7), to diagnose one contact with HIV 44.3 (95%CI 30.6-67.0), to link one newly diagnosed contact to HIV care 120 (95%CI 65.3-249.2) and to find one contact with active TB and initiate treatment 599 (95%CI 166.0-4940.7). The effectiveness of this contact tracing approach in identifying new TB and HIV cases was low. Methods to optimize contact investigation should be explored and their cost-effectiveness assessed.
76 FR 33761 - Agency Information Collection Request. 30-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-09
... behavior change, interaction design, and service innovation to increase the understanding and adoption of Comparative Effectiveness Research (CER) information by physicians and patients. By truly understanding the...
76 FR 4643 - Notice of Proposed Information Collection Requests
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-26
...): Lessons from the Research and Profiles of Promising Programs. OMB Control Number: Pending. Agency Form... grade 12 and to describe contextual factors that contribute to their effectiveness. Requests for copies...
Shah, Mansi B; Bentley, John P; McCaffrey, David J
2006-02-01
As patients continue to take a more active role in their health care, an understanding of patient requests of health care providers, including what happens when requests are not fulfilled, is becoming more important. Although its merits have been debated, direct-to-consumer advertising of prescription drugs generates patient requests. The objective of this study was to assess the influence of physician communication style, respondents' expectations of receiving a requested prescription, and perceived symptom severity on respondents' evaluations of care following a physician denial of a prescription drug request stimulated by direct-to-consumer advertising. A 2 x 2 x 2, between-subjects experimental design was used. The respondents were made up of employees of the University of Mississippi. Physician communication style, respondents' expectations, and respondents' perceived symptom severity were manipulated using vignettes. Respondents' post-visit evaluations of care were assessed by measuring trust in the physician, visit-based satisfaction with the physician, and commitment toward the physician. Factorial analysis of variance procedures for a three-way design were used to test the hypotheses and assess the research questions. Manipulation checks suggested that the independent variables were appropriately manipulated. No significant first-order or second-order interactions were noted in any of the analyses. Post-visit evaluations of care were significantly associated with physician communication style (a partnership response led to better evaluations of care). There were no significant effects of either prior expectation of request fulfillment or perceived symptom severity. However, non-significant trends in mean scores suggested a potential role of these variables in the evaluation process following request denial. The manner in which a physician communicates with an individual is an important determinant of the evaluation of care following the denial of a request. The results suggest that health care providers attempting to minimize the effect of request denials on patient evaluations should make an effort to involve the patient in the decision-making process.
12 CFR Appendix A to Part 226 - Effect on State Laws
Code of Federal Regulations, 2011 CFR
2011-01-01
... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Effect on State Laws A Appendix A to Part 226... TRUTH IN LENDING (REGULATION Z) Pt. 226, App. A Appendix A to Part 226—Effect on State Laws Request for Determination A request for a determination that a State law is inconsistent or that a State law is...
ERIC Educational Resources Information Center
Kuriscak, Lisa
2015-01-01
This study focuses on variation within a group of learners of Spanish (N = 253) who produced requests and complaints via a written discourse completion task. It examines the effects of learner and situational variables on production--the effect of proficiency and addressee-gender on speech-act choice and the effect of perception of imposition on…
ERIC Educational Resources Information Center
Ali, Emad; MacFarland, Stephanie Z.; Umbreit, John
2011-01-01
The Picture Exchange Communication System (PECS) is an augmentative and alternative communication (AAC) program used to teach functional requesting and commenting skills to people with disabilities (Bondy & Frost, 1993; Frost & Bondy, 2002). In this study, tangible symbols were added to PECS in teaching requesting to four students (ages 7-14) with…
Enabling chip-scale trace gas sensing systems with silicon photonics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Green, William
Tunable laser trace-gas spectroscopy has been effectively used in both environmental and medical applications, for its sensitivity and specificity. We’ll describe how contemporary silicon photonics manufacturing and assembly are leveraged for a cost-effective miniaturized spectroscopic sensor platform, and outline uses in fugitive methane emissions monitoring.
Physiological Effects of Trace Elements and Chemicals in Water
ERIC Educational Resources Information Center
Varma, M. M.; And Others
1976-01-01
The physiological effects on humans and animals of trace amounts of organic and unorganic pollutants in natural and waste waters are examined. The sensitivity of particular organs and species is emphasized. Substances reviewed include mercury, arsenic, cadmium, lead, chromium, fluorides, nitrates and organics, including polychlounated biphenyls.…
Hanaki, Nao; Yamashita, Kazuto; Kunisawa, Susumu; Imanaka, Yuichi
2016-12-09
In Japan, ambulance staff sometimes must make request calls to find hospitals that can accept patients because of an inadequate information sharing system. This study aimed to quantify effects of the number of request calls on the time interval between an emergency call and hospital arrival. A cross-sectional study of an ambulance records database in Nara prefecture, Japan. A total of 43 663 patients (50% women; 31.2% aged 80 years and over): (1) transported by ambulance from April 2013 to March 2014, (2) aged 15 years and over, and (3) with suspected major illness. The time from call to hospital arrival, defined as the time interval from receipt of an emergency call to ambulance arrival at a hospital. The mean time interval from emergency call to hospital arrival was 44.5 min, and the mean number of requests was 1.8. Multilevel linear regression analysis showed that ∼43.8% of variations in transportation times were explained by patient age, sex, season, day of the week, time, category of suspected illness, person calling for the ambulance, emergency status at request call, area and number of request calls. A higher number of request calls was associated with longer time intervals to hospital arrival (addition of 6.3 min per request call; p<0.001). In an analysis dividing areas into three groups, there were differences in transportation time for diseases needing cardiologists, neurologists, neurosurgeons and orthopaedists. The study revealed 6.3 additional minutes needed in transportation time for every refusal of a request call, and also revealed disease-specific delays among specific areas. An effective system should be collaboratively established by policymakers and physicians to ensure the rapid identification of an available hospital for patient transportation in order to reduce the time from the initial emergency call to hospital arrival. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Hanaki, Nao; Yamashita, Kazuto; Kunisawa, Susumu; Imanaka, Yuichi
2016-01-01
Objectives In Japan, ambulance staff sometimes must make request calls to find hospitals that can accept patients because of an inadequate information sharing system. This study aimed to quantify effects of the number of request calls on the time interval between an emergency call and hospital arrival. Design and setting A cross-sectional study of an ambulance records database in Nara prefecture, Japan. Cases A total of 43 663 patients (50% women; 31.2% aged 80 years and over): (1) transported by ambulance from April 2013 to March 2014, (2) aged 15 years and over, and (3) with suspected major illness. Primary outcome measures The time from call to hospital arrival, defined as the time interval from receipt of an emergency call to ambulance arrival at a hospital. Results The mean time interval from emergency call to hospital arrival was 44.5 min, and the mean number of requests was 1.8. Multilevel linear regression analysis showed that ∼43.8% of variations in transportation times were explained by patient age, sex, season, day of the week, time, category of suspected illness, person calling for the ambulance, emergency status at request call, area and number of request calls. A higher number of request calls was associated with longer time intervals to hospital arrival (addition of 6.3 min per request call; p<0.001). In an analysis dividing areas into three groups, there were differences in transportation time for diseases needing cardiologists, neurologists, neurosurgeons and orthopaedists. Conclusions The study revealed 6.3 additional minutes needed in transportation time for every refusal of a request call, and also revealed disease-specific delays among specific areas. An effective system should be collaboratively established by policymakers and physicians to ensure the rapid identification of an available hospital for patient transportation in order to reduce the time from the initial emergency call to hospital arrival. PMID:27940625
An audit of the completion of radiology request forms and the request practice
Akintomide, Akintunde O.; Ikpeme, Anthonia A.; Ngaji, Affiong I.; Ani, Nchiewe E.; Udofia, Appolline T.
2015-01-01
Objective: To assess the degree of utilization of the radiology request form (RRF), the extent of completion each form, the frequency of filling the fields in all the forms, and its effectiveness as a communication tool between the referring clinicians and radiologists. Materials and Methods: All the RRFs for conventional radiographic examinations were audited over a 3-month period. A database containing all the fields in the form, type of request paper used, and legibility of the physician's handwriting was created. A few resident radiologists in the plain film reporting unit were recruited to join in collecting the data daily. We used simple statistical methods to analyze the extent of completion of each form, frequency of completion of the fields in all the request forms, frequency of use of the appropriate form, and frequency of legibility of the physician's handwriting. The results are expressed in percentages. Results: Five hundred eighty (580) requests were analyzed, consisting of 180 for males and 400 for females. The most-completed request form was 86.67% filled, while the least-completed was 26.67%. The most frequently filled field was the requested examination (99.66%). Of the clinicians, 28% did not use the RRF for their referrals, while 7.37% had illegible handwriting. Conclusion: A significant number of the referring clinicians did not make the best use of the radiology department by not using the institution's approved RRF as an effective means of communication with the radiologists, mainly due to the inadequate completion of the forms. PMID:26288767
Chatelain, M; Gasparini, J; Frantz, A
2016-04-01
Understanding the effects of trace metals emitted by anthropogenic activities on wildlife is of great concern in urban ecology; yet, information on how they affect individuals, populations, communities and ecosystems remains scarce. In particular, trace metals may impact survival by altering the immune system response to parasites. Plumage melanin is assumed to influence the effects of trace metals on immunity owing to its ability to bind metal ions in feathers and its synthesis being coded by a pleiotropic gene. We thus hypothesized that trace metal exposure would interact with plumage colouration in shaping immune response. We experimentally investigated the interactive effect between exposure to an environmentally relevant range of zinc and/or lead and melanin-based plumage colouration on components of the immune system in feral pigeons (Columba livia). We found that zinc increased anti-keyhole limpet hemocyanin (KLH) IgY primary response maintenance, buffered the negative effect of lead on anti-KLH IgY secondary response maintenance and tended to increase T-cell mediated phytohaemagglutinin (PHA) skin response. Lead decreased the peak of the anti-KLH IgY secondary response. In addition, pheomelanic pigeons exhibited a higher secondary anti-KLH IgY response than did eumelanic ones. Finally, T-cell mediated PHA skin response decreased with increasing plumage eumelanin level of birds exposed to lead. Neither treatments nor plumage colouration correlated with endoparasite intensity. Overall, our study points out the effects of trace metals on some parameters of birds' immunity, independently from other confounding urbanization factors, and underlines the need to investigate their impacts on other life history traits and their consequences in the ecology and evolution of host-parasite interactions.
Improved backward ray tracing with stochastic sampling
NASA Astrophysics Data System (ADS)
Ryu, Seung Taek; Yoon, Kyung-Hyun
1999-03-01
This paper presents a new technique that enhances the diffuse interreflection with the concepts of backward ray tracing. In this research, we have modeled the diffuse rays with the following conditions. First, as the reflection from the diffuse surfaces occurs in all directions, it is impossible to trace all of the reflected rays. We confined the diffuse rays by sampling the spherical angle out of the reflected rays around the normal vector. Second, the traveled distance of reflected energy from the diffuse surface differs according to the object's property, and has a comparatively short reflection distance. Considering the fact that the rays created on the diffuse surfaces affect relatively small area, it is very inefficient to trace all of the sampled diffused rays. Therefore, we set a fixed distance as the critical distance and all the rays beyond this distance are ignored. The result of this research is that as the improved backward ray tracing can model the illumination effects such as the color bleeding effects, we can replace the radiosity algorithm under the limited environment.
Machado, W; Borrelli, N L; Ferreira, T O; Marques, A G B; Osterrieth, M; Guizan, C
2014-02-15
The degree of iron pyritization (DOP) and degree of trace metal pyritization (DTMP) were evaluated in mangrove soil profiles from an estuarine area located in Rio de Janeiro (SE Brazil). The soil pH was negatively correlated with redox potential (Eh) and positively correlated with DOP and DTMP of some elements (Mn, Cu and Pb), suggesting that pyrite oxidation generated acidity and can affect the importance of pyrite as a trace metal-binding phase, mainly in response to spatial variability in tidal flooding. Besides these aerobic oxidation effects, results from a sequential extraction analyses of reactive phases evidenced that Mn oxidized phase consumption in reaction with pyrite can be also important to determine the pyritization of trace elements. Cumulative effects of these aerobic and anaerobic oxidation processes were evidenced as factors affecting the capacity of mangrove soils to act as a sink for trace metals through pyritization processes. Copyright © 2013 Elsevier Ltd. All rights reserved.
Thornock, Bradley Steven O
2016-01-01
Whole genome sequencing (WGS) can be a cost-effective and efficient means of diagnosis for some children, but it also raises a number of ethical concerns. One such concern is how researchers derive and communicate results from WGS, including future requests for further analysis of stored sequences. The purpose of this paper is to think about what is at stake, and for whom, in any solution that is developed to deal with such requests. To accomplish this task, this paper will utilize stakeholder theory, a common method used in business ethics. Several scenarios that connect stakeholder concerns and WGS will also posited and analyzed. This paper concludes by developing criteria composed of a series of questions that researchers can answer in order to more effectively address requests for further analysis of stored sequences.
Method and apparatus for effecting light-off of a catalytic converter in a hybrid powertrain system
Roos, Bryan Nathaniel; Spohn, Brian L
2013-07-02
A powertrain system includes a hybrid transmission and an internal combustion engine coupled to an exhaust aftertreatment device. A method for operating the powertrain system includes operating the hybrid transmission to generate tractive torque responsive to an operator torque request with the internal combustion engine in an engine-off state so long as the tractive torque is less than a threshold. The internal combustion engine is operated in an engine-on state at preferred operating conditions to effect light-off of the exhaust aftertreatment device and the hybrid transmission is coincidentally operated to generate tractive torque responsive to the operator torque request when the operator torque request exceeds the threshold. The internal combustion engine is then operated in the engine-on state to generate tractive torque responsive to the operator torque request.
Bing, Haijian; Wu, Yanhong; Zhou, Jun; Li, Rui; Luo, Ji; Yu, Dong
2016-04-07
Trace metals adsorbed onto fine particles can be transported long distances and ultimately deposited in Polar Regions via the cold condensation effect. This study indicated the possible sources of silver (Ag), cadmium (Cd), copper (Cu), lead (Pb), antimony (Sb) and zinc (Zn) in soils on the eastern slope of Mt. Gongga, eastern Tibetan Plateau, and deciphered the effects of vegetation and mountain cold condensation on their distributions with elevation. The metal concentrations in the soils were comparable to other mountains worldwide except the remarkably high concentrations of Cd. Trace metals with high enrichment in the soils were influenced from anthropogenic contributions. Spatially, the concentrations of Cu and Zn in the surface horizons decreased from 2000 to 3700 m a.s.l., and then increased with elevation, whereas other metals were notably enriched in the mid-elevation area (approximately 3000 m a.s.l.). After normalization for soil organic carbon, high concentrations of Cd, Pb, Sb and Zn were observed above the timberline. Our results indicated the importance of vegetation in trace metal accumulation in an alpine ecosystem and highlighted the mountain cold trapping effect on trace metal deposition sourced from long-range atmospheric transport.
Effects of fertilizer placement on trace gas emissions from container-grown plant production
USDA-ARS?s Scientific Manuscript database
Increased trace gas emissions of carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) are widely believed to be a primary cause of global warming. Agriculture is a large contributor to these emissions; however, its role in climate change is unique in that it can act as a source of trace gas ...
Effects of fertilizer placement on trace gas emissions from nursery container production
USDA-ARS?s Scientific Manuscript database
Increased trace gas emissions of carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) are widely believed to be a primary cause of global warming. Agriculture is a large contributor to these emissions; however, its role in climate change is unique in that it can act as a source of trace gas ...
Tana Wood; W. L. Silver
2012-01-01
[1] Soil moisture is a key driver of biogeochemical processes in terrestrial ecosystems, strongly affecting carbon (C) and nutrient availability as well as trace gas production and consumption in soils. Models predict increasing drought frequency in tropical forest ecosystems, which could feed back on future climate change directly via effects on trace gasdynamics and...
Brulé, Mathieu; Bolduan, Rainer; Seidelt, Stephan; Schlagermann, Pascal; Bott, Armin
2013-01-01
Batch biochemical methane potential (BMP) assays to evaluate the methane yield of biogas substrates such as energy crops are usually carried out with undiluted inoculum. A BMP assay was performed on two energy crops (green cuttings and grass silage). Anaerobic digestion was performed both with and without supplementation of three commercial additives containing trace metals in liquid, solid or adsorbed form (on clay particles). In order to reveal positive effects of trace metal supplementation on the methane yield, besides undiluted inoculum, 3-fold and 10-fold dilutions of the inoculum were applied for substrate digestion. Diluted inoculum variants were supplemented with both mineral nutrients and pH-buffering substances to prevent a collapse of the digestion process. As expected, commercial additives had no effect on the digestion process performed with undiluted inoculum, while significant increases of methane production through trace element supplementation could be observed on the diluted variants. The effect of inoculum dilution may be twofold: (1) decrease in trace metal supplementation from the inoculum and (2) reduction in the initial number of bacterial cells. Bacteria require higher growth rates for substrate degradation and hence have higher trace element consumption. According to common knowledge of the biogas process, periods with volatile fatty acids accumulation and decreased pH may have occurred in the course ofanaerobic digestion. These effects may have led to inhibition, not only ofmethanogenes and acetogenes involved in the final phases of methane production, but also offibre-degrading bacterial strains involved in polymer hydrolysis. Further research is required to confirm this hypothesis.
NASA Astrophysics Data System (ADS)
Li, Tao; Wang, Yan; Zhou, Jie; Wang, Tao; Ding, Aijun; Nie, Wei; Xue, Likun; Wang, Xinfeng; Wang, Wenxing
2017-03-01
Aerosols and cloud water were analyzed at a mountaintop in the planetary boundary layer in southern China during March-May 2009, when two Asian dust storms occurred, to investigate the effects of aerosol-cloud interactions (ACIs) on chemical evolution of atmospheric trace elements. Fe, Al, and Zn predominated in both coarse and fine aerosols, followed by high concentrations of toxic Pb, As, and Cd. Most of these aerosol trace elements, which were affected by dust storms, exhibited various increases in concentrations but consistent decreases in solubility. Zn, Fe, Al, and Pb were the most abundant trace elements in cloud water. The trace element concentrations exhibited logarithmic inverse relationships with the cloud liquid water content and were found highly pH dependent with minimum concentrations at the threshold of pH 5.0. The calculation of Visual MINTEQ model showed that 80.7-96.3% of Fe(II), Zn(II), Pb(II), and Cu(II) existed in divalent free ions, while 71.7% of Fe(III) and 71.5% of Al(III) were complexed by oxalate and fluoride, respectively. ACIs could markedly change the speciation distributions of trace elements in cloud water by pH modification. The in-cloud scavenging of aerosol trace elements likely reached a peak after the first 2-3 h of cloud processing, with scavenging ratios between 0.12 for Cr and 0.57 for Pb. The increases of the trace element solubility (4-33%) were determined in both in-cloud aerosols and postcloud aerosols. These results indicated the significant importance of aerosol-cloud interactions to the evolution of trace elements during the first several cloud condensation/evaporation cycles.
Progress of pharmacogenomic research related to minerals and trace elements.
Zeng, Mei-Zi; Tang, Jie; Liu, Zhao-Qian; Zhou, Hong-Hao; Zhang, Wei
2015-10-01
Pharmacogenomics explores the variations in both the benefits and the adverse effects of a drug among patients in a target population by analyzing genomic profiles of individual patients. Minerals and trace elements, which can be found in human tissues and maintain normal physiological functions, are also in the focus of pharmacogenomic research. Single-nucleotide polymorphisms (SNPs) affect the metabolism, disposition and efficacy of minerals and trace elements in humans, resulting in changes of body function. This review describes some of the recent progress in pharmacogenomic research related to minerals and trace elements.
CometQuest: A Rosetta Adventure
NASA Technical Reports Server (NTRS)
Leon, Nancy J.; Fisher, Diane K.; Novati, Alexander; Chmielewski, Artur B.; Fitzpatrick, Austin J.; Angrum, Andrea
2012-01-01
This software is a higher-performance implementation of tiled WMS, with integral support for KML and time-varying data. This software is compliant with the Open Geospatial WMS standard, and supports KML natively as a WMS return type, including support for the time attribute. Regionated KML wrappers are generated that match the existing tiled WMS dataset. Ping and JPG formats are supported, and the software is implemented as an Apache 2.0 module that supports a threading execution model that is capable of supporting very high request rates. The module intercepts and responds to WMS requests that match certain patterns and returns the existing tiles. If a KML format that matches an existing pyramid and tile dataset is requested, regionated KML is generated and returned to the requesting application. In addition, KML requests that do not match the existing tile datasets generate a KML response that includes the corresponding JPG WMS request, effectively adding KML support to a backing WMS server.
NASA Technical Reports Server (NTRS)
Plesea, Lucian
2012-01-01
This software is a higher-performance implementation of tiled WMS, with integral support for KML and time-varying data. This software is compliant with the Open Geospatial WMS standard, and supports KML natively as a WMS return type, including support for the time attribute. Regionated KML wrappers are generated that match the existing tiled WMS dataset. Ping and JPG formats are supported, and the software is implemented as an Apache 2.0 module that supports a threading execution model that is capable of supporting very high request rates. The module intercepts and responds to WMS requests that match certain patterns and returns the existing tiles. If a KML format that matches an existing pyramid and tile dataset is requested, regionated KML is generated and returned to the requesting application. In addition, KML requests that do not match the existing tile datasets generate a KML response that includes the corresponding JPG WMS request, effectively adding KML support to a backing WMS server.
Blocking performance approximation in flexi-grid networks
NASA Astrophysics Data System (ADS)
Ge, Fei; Tan, Liansheng
2016-12-01
The blocking probability to the path requests is an important issue in flexible bandwidth optical communications. In this paper, we propose a blocking probability approximation method of path requests in flexi-grid networks. It models the bundled neighboring carrier allocation with a group of birth-death processes and provides a theoretical analysis to the blocking probability under variable bandwidth traffic. The numerical results show the effect of traffic parameters to the blocking probability of path requests. We use the first fit algorithm in network nodes to allocate neighboring carriers to path requests in simulations, and verify approximation results.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-20
... biodiesel, water/diesel emulsions, several atypical additives, and renewable gasoline and diesel fuels. Tier... health effects. Tier 2 data have been submitted for baseline diesel, biodiesel, and water/diesel...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-01
... Federal agencies, and to improve the effectiveness of job training programs. This ICR requests minor... of Labor (DOL) is submitting the Employment and Training Administration (ETA) sponsored information...
Patient-initiated electronic health record amendment requests
Hanauer, David A; Preib, Rebecca; Zheng, Kai; Choi, Sung W
2014-01-01
Background and objective Providing patients access to their medical records offers many potential benefits including identification and correction of errors. The process by which patients ask for changes to be made to their records is called an ‘amendment request’. Little is known about the nature of such amendment requests and whether they result in modifications to the chart. Methods We conducted a qualitative content analysis of all patient-initiated amendment requests that our institution received over a 7-year period. Recurring themes were identified along three analytic dimensions: (1) clinical/documentation area, (2) patient motivation for making the request, and (3) outcome of the request. Results The dataset consisted of 818 distinct requests submitted by 181 patients. The majority of these requests (n=636, 77.8%) were made to rectify incorrect information and 49.7% of all requests were ultimately approved. In 6.6% of the requests, patients wanted valid information removed from their record, 27.8% of which were approved. Among all of the patients requesting a copy of their chart, only a very small percentage (approximately 0.2%) submitted an amendment request. Conclusions The low number of amendment requests may be due to inadequate awareness by patients about how to make changes to their records. To make this approach effective, it will be important to inform patients of their right to view and amend records and about the process for doing so. Increasing patient access to medical records could encourage patient participation in improving the accuracy of medical records; however, caution should be used. PMID:24863430
Balcom, Jessica R; Veach, Patricia McCarthy; Bemmels, Heather; Redlinger-Grosse, Krista; LeRoy, Bonnie S
2013-06-01
A limited amount of research indicates patient requests play a major role in genetic counselors' self-disclosure decisions and that disclosure and non-disclosure responses to patient requests may differentially affect genetic counseling processes. Studies further suggest patient requests may be more common in prenatal settings, particularly when counselors are pregnant. Empirical evidence is limited however, concerning the nature of patient requests. This study explored genetic counselors' experiences of prenatal patients' requests for self-disclosure. Four major research questions were: (1) What types of questions do prenatal patients ask that invite self-disclosure?; (2) Do pregnant genetic counselors have unique experiences with prenatal patient disclosure requests?; (3) How do genetic counselors typically respond to disclosure requests?; and (4) What strategies are effective and ineffective in responding to disclosure requests? One hundred seventy-six genetic counselors completed an online survey and 40 also participated in telephone interviews. Inductive analysis of 21 interviews revealed patient questions vary, although questions about counselor demographics are most common, and patients are more likely to ask pregnant counselors questions about their personal pregnancy decisions. Participants reported greater discomfort with self-disclosure requests during pregnancy, yet also disclosing more frequently during pregnancy. Counselor responses included personal self-disclosure, professional self-disclosure, redirection, and declining to disclose. Factors perceived as influencing disclosure included: topic, patient motivations, timing of request, quality of counseling relationship, patient characteristics, and ethical/legal responsibilities. Disclosure practices changed over time for most counselors. Additional findings, practice implications, and research recommendations are discussed.
NASA Astrophysics Data System (ADS)
Wiche, Oliver; Székely, Balazs; Moschner, Christin; Heilmeier, Hermann
2015-04-01
In recent studies root-soil interactions of white lupine (Lupinus albus L.) have drawn special attention to researchers due to its particularly high potential to increase bioavailability of phosphorous (P) and trace nutrients in soils. In mixed cultures, white lupine has the ability to mobilize P and trace nutrients in soil in excess of its own need and make this excess available for other intercropped companion species. While improved acquisition of P and improved yield parameters have mostly been documented in cereal-lupine intercrops, compared to sole crops, only a few recent studies have evidenced similar effects for trace elements e.g. Fe, Zn and Mn. In this preliminary study we tried to obtain more information about the mobilization of trace elements due to intercropping under field conditions. We hypothesize, that processes that lead to a better acquisition of trace nutrients might also affect other trace elements what could be useful for phytoremediation and phytomining research. Here we report the results of a semi-field experiment were we investigated the effects of an intercropping of white lupine with oat (Avena sativa L.) on the concentrations of trace metals in shoots of oat. We investigated the effects on 12 trace elements, including 4 elements with relevance for plant nutrition (P, Fe, Mn, Zn) and 8 trace elements, belonging to the group of metalloids, lanthanides and actinides with high relevance in phytoremediation (Cd, Pb Th, U) and phytomining research (Sc, La, Nd, Ge). The experiment was carried out on a semi-field lysimer at the off-site soil recycling and remediation center in Hirschfeld (Saxony, Germany). To test the intercropping-dependent mobilization of trace metals in soil and enhanced uptake of elements by oat, white lupine and oat were cultivated on 20 plots (4 m² each) in monocultures and mixed cultures and two different white lupin /oat-ratios (11% and 33%, respectively) applying various treatments. The geometrical arrangement of plots was randomized and every treatment was fivefold replicated. Soil solution was collected weekly with plastic suction cups. Concentrations of trace metals in shoots of oat and soil solution were measured with ICP-MS. As a result, we found that both, concentrations of trace elements in oat plants, as well as the mobility of P and trace metals in soil solution was increased by an intercropping with white lupine. Mixed culture of oat with 11% white lupin significantly increased the concentrations of the trace nutrients Fe, Mn and Zn, as well as the concentrations of the trace metals Pb, La, Nd, Sc, Th and U in tissues of oat. Surprisingly, mixed cultures with 33 % white lupin did not significantly affect trace metal concentrations in oat, what might be the consequence of an increasing competition of roots of white lupin and oat for nutrients and trace metals. In conclusion we found that mixed cultures of white lupin with cereals might be a powerful tool for enhanced phytoremediation and phytomining. However, processes involved in the physiochemical mechanism of element uptake as affected by the oat/white lupin co-cultivation remain unknown and further studies on this topic are planned. These studies have been carried out in the framework of the PhytoGerm project, financed by the Federal Ministry of Education and Research, Germany. The authors are grateful to students and laboratory assistants contributing in the field work and sample preparation.
Trace elements in Mediterranean seagrasses and macroalgae. A review.
Bonanno, Giuseppe; Orlando-Bonaca, Martina
2018-03-15
This review investigates the current state of knowledge on the levels of the main essential and non-essential trace elements in Mediterranean vascular plants and macroalgae. The research focuses also on the so far known effects of high element concentrations on these marine organisms. The possible use of plants and algae as bioindicators of marine pollution is discussed as well. The presence of trace elements is overall well known in all five Mediterranean vascular plants, whereas current studies investigated element concentrations in only c. 5.0% of all native Mediterranean macroalgae. Although seagrasses and macroalgae can generally accumulate and tolerate high concentrations of trace elements, phytotoxic levels are still not clearly identified for both groups of organisms. Moreover, although the high accumulation of trace elements in seagrasses and macroalgae is considered as a significant risk for the associated food webs, the real magnitude of this risk has not been adequately investigated yet. The current research provides enough scientific evidence that seagrasses and macroalgae may act as effective bioindicators, especially the former for trace elements in sediments, and the latter in seawater. The combined use of seagrasses and macroalgae as bioindicators still lacks validated protocols, whose application should be strongly encouraged to biomonitor exhaustively the presence of trace elements in the abiotic and biotic components of coastal ecosystems. Copyright © 2017 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Biria, Reza; Ameri-Golestan, Ahmad; Antón-Méndez, Inés
2010-01-01
This study examines the impact of syntactic priming on production of indirect questions/requests by Persian learners of English as a foreign language. Eighty learners participated in two experiments investigating the impact of syntactic priming on oral production and the possibility of transfer of the priming effects to a different modality.…
20 CFR 405.383 - Effect of dismissal of a request for a hearing before an administrative law judge.
Code of Federal Regulations, 2010 CFR
2010-04-01
... hearing before an administrative law judge. 405.383 Section 405.383 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Administrative Law Judge Hearing § 405.383 Effect of dismissal of a request for a hearing before an administrative law judge. The...
Code of Federal Regulations, 2011 CFR
2011-01-01
... CHANGE IN BANK CONTROL (REGULATION Y) Regulations Financial Holding Companies § 225.89 How to request... holding company and to the financial system generally; (5) Describe the potential adverse effects... effects. (c) Board action. The Board will inform the financial holding company in writing of the Board's...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-18
... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 20 [DA 10-1936; WT Docket No. 07-250] Hearing Aid... Telecommunications Bureau requests that the comments in the pending Hearing Aid Compatibility proceeding address the effects of the Twenty-First Century Communications and Video Accessibility Act of 2010, if any, on the...
Atmospheric transport of trace elements and nutrients to the oceans
Chance, R.
2016-01-01
This paper reviews atmospheric inputs of trace elements and nutrients to the oceans in the context of the GEOTRACES programme and provides new data from two Atlantic GEOTRACES cruises. We consider the deposition of nitrogen to the oceans, which is now dominated by anthropogenic emissions, the deposition of mineral dust and related trace elements, and the deposition of other trace elements which have a mixture of anthropogenic and dust sources. We then consider the solubility (as a surrogate for bioavailability) of the various elements. We consider briefly the sources, atmospheric transport and transformations of these elements and how this results in strong spatial deposition gradients. Solubility of the trace elements also varies systematically between elements, reflecting their sources and cycling, and for some trace elements there are also systematic gradients in solubility related to dust loading. Together, these effects create strong spatial gradients in the inputs of bioavailable trace elements to the oceans, and we are only just beginning to understand how these affect ocean biogeochemistry. This article is part of the themed issue ‘Biological and climatic impacts of ocean trace element chemistry’. PMID:29035252
Influence of trace elements on dental enamel properties: A review.
Qamar, Zeeshan; Haji Abdul Rahim, Zubaidah Binti; Chew, Hooi Pin; Fatima, Tayyaba
2017-01-01
Dental enamel, an avascular, irreparable, outermost and protective layer of the human clinical crown has a potential to withstand the physico-chemical effects and forces. These properties are being regulated by a unique association among elements occurring in the crystallites setup of human dental enamel. Calcium and phosphate are the major components (hydroxyapatite) in addition to some trace elements which have a profound effect on enamel. The current review was planned to determine the aptitude of various trace elements to substitute and their influence on human dental enamel in terms of physical and chemical properties.
Effects of Humidity Swings on Adsorption Columns for Air Revitalization: Modeling and Experiments
NASA Technical Reports Server (NTRS)
LeVan, M. Douglas; Finn, John E.
1997-01-01
Air purification systems are necessary to provide clean air in the closed environments aboard spacecraft. Trace contaminants are removed using adsorption. One major factor concerning the removal of trace contaminants is relative humidity. Water can reduce adsorption capacity and, due to constant fluctuations, its presence is difficult to incorporate into adsorption column designs. The purpose of the research was to allow for better design techniques in trace contaminant adsorption systems, especially for feeds with water present. Experiments and mathematical modeling research on effects of humidity swings on adsorption columns for air revitalization were carried out.
Architecture and the Information Revolution.
ERIC Educational Resources Information Center
Driscoll, Porter; And Others
1982-01-01
Traces how technological changes affect the architecture of the workplace. Traces these effects from the industrial revolution up through the computer revolution. Offers suggested designs for the computerized office of today and tomorrow. (JM)
Ivanina, Anna V; Beniash, Elia; Etzkorn, Markus; Meyers, Tiffany B; Ringwood, Amy H; Sokolova, Inna M
2013-09-15
Estuarine and coastal habitats experience large fluctuations of environmental factors such as temperature, salinity, partial pressure of CO2 ( [Formula: see text] ) and pH; they also serve as the natural sinks for trace metals. Benthic filter-feeding organisms such as bivalves are exposed to the elevated concentrations of metals in estuarine water and sediments that can strongly affect their physiology. The effects of metals on estuarine organisms may be exacerbated by other environmental factors. Thus, a decrease in pH caused by high [Formula: see text] (hypercapnia) can modulate the effects of trace metals by affecting metal bioavailability, accumulation or binding. To better understand the cellular mechanisms of interactions between [Formula: see text] and trace metals in marine bivalves, we exposed isolated mantle cells of the hard clams (Mercenaria mercenaria) to different levels of [Formula: see text] (0.05, 1.52 and 3.01 kPa) and two major trace metal pollutants - cadmium (Cd) and copper (Cu). Elevated [Formula: see text] resulted in a decrease in intracellular pH (pHi) of the isolated mantle cells from 7.8 to 7.4. Elevated [Formula: see text] significantly but differently affected the trace metal accumulation by the cells. Cd uptake was suppressed at elevated [Formula: see text] levels while Cu accumulation has greatly accelerated under hypercapnic conditions. Interestingly, at higher extracellular Cd levels, labile intracellular Cd(2+) concentration remained the same, while intracellular levels of free Zn(2+) increased suggesting that Cd(2+) substitutes bound Zn(2+) in these cells. In contrast, Cu exposure did not affect intracellular Zn(2+) but led to a profound increase in the intracellular levels of labile Cu(2+) and Fe(2+). An increase in the extracellular concentrations of Cd and Cu led to the elevated production of reactive oxygen species under the normocapnic conditions (0.05 kPa [Formula: see text] ); surprisingly, this effect was mitigated in hypercapnia (1.52 and 3.01 kPa). Overall, our data reveal complex and metal-specific interactions between the cellular effects of trace metals and [Formula: see text] in clams and indicate that variations in environmental [Formula: see text] may modulate the biological effects of trace metals in marine organisms. Copyright © 2013 Elsevier B.V. All rights reserved.
Tracing the Attention of Moving Citizens
NASA Astrophysics Data System (ADS)
Wu, Lingfei; Wang, Cheng-Jun
2016-09-01
With the widespread use of mobile computing devices in contemporary society, our trajectories in the physical space and virtual world are increasingly closely connected. Using the anonymous smartphone data of 1 × 105 users in a major city of China, we study the interplay between online and offline human behaviors by constructing the mobility network (offline) and the attention network (online). Using the network renormalization technique, we find that they belong to two different classes: the mobility network is small-world, whereas the attention network is fractal. We then divide the city into different areas based on the features of the mobility network discovered under renormalization. Interestingly, this spatial division manifests the location-based online behaviors, for example shopping, dating, and taxi-requesting. Finally, we offer a geometric network model to help us understand the relationship between small-world and fractal networks.
Chemical data for bottom sediment in Mountain Creek Lake, Dallas, Texas, 1999-2000
Wilson, Jennifer T.
2002-01-01
Mountain Creek Lake is a reservoir adjacent to the Naval Weapons Industrial Reserve Plant and the former Naval Air Station in Dallas, Texas. The U.S. Geological Survey began studies of water, sediment, and biota in the reservoir in 1994 after a Resource Conservation and Recovery Act Facility Investigation detected concentrations of organic chemicals on both facilities. Additional reservoir bottom sediment samples were collected during December 1999–January 2000 at the request of the Southern Division Naval Facilities Engineering Command to further define the occurrence and distribution of selected constituents and to supplement available data. The U.S. Geological Survey National Water Quality Laboratory analyzed bottom-sediment samples from 16 box cores and 5 gravity cores for major and trace elements, organochlorine pesticides, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, grain size, and cesium-137.
AmO 2 Analysis for Analytical Method Testing and Assessment: Analysis Support for AmO 2 Production
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kuhn, Kevin John; Bland, Galey Jean; Fulwyler, James Brent
Americium oxide samples will be measured for various analytes to support AmO 2 production. The key analytes that are currently requested by the Am production customer at LANL include total Am content, Am isotopics, Pu assay, Pu isotopics, and trace element content including 237Np content. Multiple analytical methods will be utilized depending on the sensitivity, accuracy and precision needs of the Am matrix. Traceability to the National Institute of Standards and Technology (NIST) will be achieved, where applicable, by running NIST traceable quality control materials. This given that there are no suitable AmO 2 reference materials currently available for requestedmore » analytes. The primary objective is to demonstrate the suitability of actinide analytical chemistry methods to support AmO 2 production operations.« less
Wolfe, Caitlin M; Hamblion, Esther L; Schulte, Jacqueline; Williams, Parker; Koryon, Augustine; Enders, Jonathan; Sanor, Varlee; Wapoe, Yatta; Kwayon, Dash; Blackley, David J; Laney, Anthony S; Weston, Emily J; Dokubo, Emily K; Davies-Wayne, Gloria; Wendland, Annika; Daw, Valerie T S; Badini, Mehboob; Clement, Peter; Mahmoud, Nuha; Williams, Desmond; Gasasira, Alex; Nyenswah, Tolbert G; Fallah, Mosoka
2017-06-01
Contact tracing is one of the key response activities necessary for halting Ebola Virus Disease (EVD) transmission. Key elements of contact tracing include identification of persons who have been in contact with confirmed EVD cases and careful monitoring for EVD symptoms, but the details of implementation likely influence their effectiveness. In November 2015, several months after a major Ebola outbreak was controlled in Liberia, three members of a family were confirmed positive for EVD in the Duport Road area of Monrovia. The cluster provided an opportunity to implement and evaluate modified approaches to contact tracing. The approaches employed for improved contact tracing included classification and risk-based management of identified contacts (including facility based isolation of some high risk contacts, provision of support to persons being monitored, and school-based surveillance for some persons with potential exposure but not listed as contacts), use of phone records to help locate missing contacts, and modifications to data management tools. We recorded details about the implementation of these approaches, report the overall outcomes of the contact tracing efforts and the challenges encountered, and provide recommendations for management of future outbreaks. 165 contacts were identified (with over 150 identified within 48 hours of confirmation of the EVD cases) and all initially missing contacts were located. Contacts were closely monitored and promptly tested if symptomatic; no contacts developed disease. Encountered challenges related to knowledge gaps among contact tracing staff, data management, and coordination of contact tracing activities with efforts to offer Ebola vaccine. The Duport Road EVD cluster was promptly controlled. Missing contacts were effectively identified, and identified contacts were effectively monitored and rapidly tested. There is a persistent risk of EVD reemergence in Liberia; the experience controlling each cluster can help inform future Ebola control efforts in Liberia and elsewhere.
Burton, Carmen; Hoefen, Todd M.; Plumlee, Geoffrey S.; Baumberger, Katherine L.; Backlin, Adam R.; Gallegos, Elizabeth; Fisher, Robert N.
2016-01-01
Most research on the effects of wildfires on stream water quality has focused on suspended sediment and nutrients in streams and water bodies, and relatively little research has examined the effects of wildfires on trace elements. The purpose of this study was two-fold: 1) to determine the effect of the 2009 Station Fire in the Angeles National Forest northeast of Los Angeles, CA on trace element concentrations in streams, and 2) compare trace elements in post-fire stormflow water quality to criteria for aquatic life to determine if trace elements reached concentrations that can harm aquatic life. Pre-storm and stormflow water-quality samples were collected in streams located inside and outside of the burn area of the Station Fire. Ash and burned soil samples were collected from several locations within the perimeter of the Station Fire. Filtered concentrations of Fe, Mn, and Hg and total concentrations of most trace elements in storm samples were elevated as a result of the Station Fire. In contrast, filtered concentrations of Cu, Pb, Ni, and Se and total concentrations of Cu were elevated primarily due to storms and not the Station Fire. Total concentrations of Se and Zn were elevated as a result of both storms and the Station Fire. Suspended sediment in stormflows following the Station Fire was an important transport mechanism for trace elements. Cu, Pb, and Zn primarily originate from ash in the suspended sediment. Fe primarily originates from burned soil in the suspended sediment. As, Mn, and Ni originate from both ash and burned soil. Filtered concentrations of trace elements in stormwater samples affected by the Station Fire did not reach levels that were greater than criteria established for aquatic life. Total concentrations for Fe, Pb, Ni, and Zn were detected at concentrations above criteria established for aquatic life.
Stefanello, C; Santos, T C; Murakami, A E; Martins, E N; Carneiro, T C
2014-01-01
This study was carried out with the purpose of evaluating the effect of supplementing hens' diets with trace minerals from inorganic or organic sources on the productive performance, eggshell quality, and eggshell ultrastructure of laying hens. Three hundred sixty Hy-Line W36 laying hens between 47 to 62 wk of age were used and distributed in a completely randomized experimental design with 9 treatments, 5 replicates, and 8 birds for each experimental unit. The treatments consisted of a control diet without supplementation of the trace minerals Mn, Zn, and Cu; 4 supplementation levels of these trace minerals from an inorganic source; and the same levels of supplementation from an organic source (proteinates). The supplementation levels in milligrams per kilogram for Mn, Zn, and Cu, were, respectively, 35-30-05, 65-60-10, 95-90-15, and 125-120-20. There was no effect of supplementation of trace minerals on the rate of posture, feed intake, feed conversion, specific weight, and Haugh unit of eggs. However, there was a quadratic effect (P < 0.05) of the levels of trace mineral supplementation on average egg weight and egg mass; the results did not differ regarding the source used. The increase in the levels of supplementation of Mn, Zn, and Cu provided a linear increase (P < 0.05) in the breaking strength and the percentage of eggshell. There was a linear decrease (P < 0.05) in the egg loss and the number of mammillary buttons in the shell. The best results were obtained using diets supplemented with trace minerals from an organic source because these diets provided lower egg loss, higher thickness, and increased strength of the shell. Structurally, organic Mn, Zn, and Cu provided higher thickness of the palisade layer and lower mammillary density. The trace mineral supplementation improved the structural characteristics and the quality of the eggshells.
Schulte, Jacqueline; Williams, Parker; Koryon, Augustine; Enders, Jonathan; Sanor, Varlee; Wapoe, Yatta; Kwayon, Dash; Blackley, David J.; Laney, Anthony S.; Weston, Emily J.; Dokubo, Emily K.; Davies-Wayne, Gloria; Wendland, Annika; Daw, Valerie T. S.; Badini, Mehboob; Clement, Peter; Mahmoud, Nuha; Williams, Desmond; Gasasira, Alex; Nyenswah, Tolbert G.; Fallah, Mosoka
2017-01-01
Background Contact tracing is one of the key response activities necessary for halting Ebola Virus Disease (EVD) transmission. Key elements of contact tracing include identification of persons who have been in contact with confirmed EVD cases and careful monitoring for EVD symptoms, but the details of implementation likely influence their effectiveness. In November 2015, several months after a major Ebola outbreak was controlled in Liberia, three members of a family were confirmed positive for EVD in the Duport Road area of Monrovia. The cluster provided an opportunity to implement and evaluate modified approaches to contact tracing. Methods The approaches employed for improved contact tracing included classification and risk-based management of identified contacts (including facility based isolation of some high risk contacts, provision of support to persons being monitored, and school-based surveillance for some persons with potential exposure but not listed as contacts), use of phone records to help locate missing contacts, and modifications to data management tools. We recorded details about the implementation of these approaches, report the overall outcomes of the contact tracing efforts and the challenges encountered, and provide recommendations for management of future outbreaks. Results 165 contacts were identified (with over 150 identified within 48 hours of confirmation of the EVD cases) and all initially missing contacts were located. Contacts were closely monitored and promptly tested if symptomatic; no contacts developed disease. Encountered challenges related to knowledge gaps among contact tracing staff, data management, and coordination of contact tracing activities with efforts to offer Ebola vaccine. Conclusions The Duport Road EVD cluster was promptly controlled. Missing contacts were effectively identified, and identified contacts were effectively monitored and rapidly tested. There is a persistent risk of EVD reemergence in Liberia; the experience controlling each cluster can help inform future Ebola control efforts in Liberia and elsewhere. PMID:28575034
Burton, Carmen A.; Hoefen, Todd M.; Plumlee, Geoffrey S.; Baumberger, Katherine L.; Backlin, Adam R.; Gallegos, Elizabeth; Fisher, Robert N.
2016-01-01
Most research on the effects of wildfires on stream water quality has focused on suspended sediment and nutrients in streams and water bodies, and relatively little research has examined the effects of wildfires on trace elements. The purpose of this study was two-fold: 1) to determine the effect of the 2009 Station Fire in the Angeles National Forest northeast of Los Angeles, CA on trace element concentrations in streams, and 2) compare trace elements in post-fire stormflow water quality to criteria for aquatic life to determine if trace elements reached concentrations that can harm aquatic life. Pre-storm and stormflow water-quality samples were collected in streams located inside and outside of the burn area of the Station Fire. Ash and burned soil samples were collected from several locations within the perimeter of the Station Fire. Filtered concentrations of Fe, Mn, and Hg and total concentrations of most trace elements in storm samples were elevated as a result of the Station Fire. In contrast, filtered concentrations of Cu, Pb, Ni, and Se and total concentrations of Cu were elevated primarily due to storms and not the Station Fire. Total concentrations of Se and Zn were elevated as a result of both storms and the Station Fire. Suspended sediment in stormflows following the Station Fire was an important transport mechanism for trace elements. Cu, Pb, and Zn primarily originate from ash in the suspended sediment. Fe primarily originates from burned soil in the suspended sediment. As, Mn, and Ni originate from both ash and burned soil. Filtered concentrations of trace elements in stormwater samples affected by the Station Fire did not reach levels that were greater than criteria established for aquatic life. Total concentrations for Fe, Pb, Ni, and Zn were detected at concentrations above criteria established for aquatic life. PMID:27144270
Vertex shading of the three-dimensional model based on ray-tracing algorithm
NASA Astrophysics Data System (ADS)
Hu, Xiaoming; Sang, Xinzhu; Xing, Shujun; Yan, Binbin; Wang, Kuiru; Dou, Wenhua; Xiao, Liquan
2016-10-01
Ray Tracing Algorithm is one of the research hotspots in Photorealistic Graphics. It is an important light and shadow technology in many industries with the three-dimensional (3D) structure, such as aerospace, game, video and so on. Unlike the traditional method of pixel shading based on ray tracing, a novel ray tracing algorithm is presented to color and render vertices of the 3D model directly. Rendering results are related to the degree of subdivision of the 3D model. A good light and shade effect is achieved by realizing the quad-tree data structure to get adaptive subdivision of a triangle according to the brightness difference of its vertices. The uniform grid algorithm is adopted to improve the rendering efficiency. Besides, the rendering time is independent of the screen resolution. In theory, as long as the subdivision of a model is adequate, cool effects as the same as the way of pixel shading will be obtained. Our practical application can be compromised between the efficiency and the effectiveness.
ERIC Educational Resources Information Center
Spudich, Thomas M.; Herrmann, Jennifer K.; Fietkau, Ronald; Edwards, Grant A.
2004-01-01
An experiment is conducted to ascertain trace-level Pb in samples of bovine liver or muscle by applying graphite furnace atomic absorption spectrophotometry (GFAAS). The primary objective is to display the effects of physical and spectral intrusions in determining trace elements, and project the usual methods employed to minimize accuracy errors…
Hunt, Pamela S; Barnet, Robert C
2015-09-01
Animal models of Fetal Alcohol Spectrum Disorders (FASD) afford the unique capacity to precisely control timing of alcohol exposure and alcohol exposure amounts in the developing animal. These models have powerfully informed neurophysiological alterations associated with fetal and perinatal alcohol. In two experiments presented here we expand use of the Pavlovian Trace Conditioning procedure to examine cognitive deficits and intervention strategies in a rat model of FASD. Rat pups were exposed to 5g/kg/day ethanol on postnatal days (PD) 4-9, simulating alcohol exposure in the third trimester in humans. During early adolescence, approximately PD 30, the rats were trained in the trace conditioning task in which a light conditioned stimulus (CS) and shock unconditioned stimulus (US) were paired but separated by a 10-s stimulus free trace interval. Learning was assessed in freezing behavior during shock-free tests. Experiment 1 revealed that neonatal ethanol exposure significantly impaired hippocampus-dependent trace conditioning relative to controls. In Experiment 2 a serial compound conditioning procedure known as 'gap filling' completely reversed the ethanol-induced deficit in trace conditioning. We also discuss prior data regarding the beneficial effects of supplemental choline and novel preliminary data regarding the pharmacological cognitive enhancer physostigmine, both of which mitigate the alcohol-induced cognitive deficit otherwise seen in trace conditioning controls. We suggest trace conditioning as a useful tool for characterizing some of the core cognitive deficits seen in FASD, and as a model for developing effective environmental as well as nutritional and pharmacological interventions. Copyright © 2014 Elsevier Inc. All rights reserved.
Hunt, Pamela S.; Barnet, Robert C.
2014-01-01
Animal models of Fetal Alcohol Spectrum Disorders (FASD) afford the unique capacity to precisely control timing of alcohol exposure and alcohol exposure amounts in the developing animal. These models have powerfully informed neurophysiological alterations associated with fetal and perinatal alcohol. In two experiments presented here we expand use of the Pavlovian Trace Conditioning procedure to examine cognitive deficits and intervention strategies in a rat model of FASD. Rat pups were exposed to 5 g/kg/day ethanol on postnatal days (PD) 4–9, simulating alcohol exposure in the third trimester in humans. During early adolescence, approximately PD 30, the rats were trained in the trace conditioning task in which a light conditioned stimulus (CS) and shock unconditioned stimulus (US) were paired but separated by a 10-s stimulus free trace interval. Learning was assessed in freezing behavior during shock-free tests. Experiment 1 revealed that neonatal ethanol exposure significantly impaired hippocampus-dependent trace conditioning relative to controls. In Experiment 2 a serial compound conditioning procedure known as ‘gap filling’ completely reversed the ethanol-induced deficit in trace conditioning. We also discuss prior data regarding the beneficial effects of supplemental choline and novel preliminary data regarding the pharmacological cognitive enhancer physostigmine, both of which mitigate the alcohol-induced cognitive deficit otherwise seen in trace conditioning controls. We suggest trace conditioning as a useful tool for characterizing some of the core cognitive deficits seen in FASD, and as a model for developing effective environmental as well as nutritional and pharmacological interventions. PMID:25477227
77 FR 72343 - Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-05
... Technical... Tribenuron-methyl. 010466-00024 Ultrafresh 300 DD Triclosan/ Nonionic. Tributyltin oxide (no... adverse effect on the environment. The registrants in Table 2 of Unit II. have requested that EPA waive...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-09
... for biodiesel, water/diesel emulsions, several atypical additives, and renewable gasoline and diesel... adverse health effects. Tier 2 data have been submitted for baseline diesel, biodiesel, and water/diesel...
Huque, Roksana; Munshi, M. Kamruzzaman; Khatun, Afifa; Islam, Mahfuza; Hossain, Afzal; Hossain, Arzina; Akter, Shirin; Kabir, Jamiul; Nahar Jolly, Yeasmin; Islam, Ashraful
2014-01-01
Trace metals concentration and proximate composition of raw and boiled silver pomfret (Pampus argenteus) from coastal area and retail market were determined to gain the knowledge of the risk and benefits associated with indiscriminate consumption of marine fishes. The effects of cooking (boiling) on trace metal and proximate composition of silver pomfret fish were also investigated. Trace element results were determined by the Energy Dispersive X-ray Fluorescence (EDXRF) Spectrometer wherein fish samples from both areas exceeded the standard limits set by FAO/WHO for manganese, lead, cadmiumm and chromium and boiling has no significant effects on these three metal concentrations. Long-term intake of these contaminated fish samples can pose a health risk to humans who consume them. PMID:26904650
Alhidary, Ibrahim A; Abdelrahman, Mutassim M; Harron, Raafat M
2016-04-01
A study was conducted to evaluate the effects of a long-acting trace mineral rumen bolus (TMB) supplement on the productive performance, metabolic profiles, and trace mineral status of growing camels under natural grazing conditions. Fifteen 6-month-old growing male camels (average bodyweight 139.51 ± 26.49 kg) were used in a 150-day trial. Animals were individually housed in a shaded pen and randomly assigned to receive zero (control group, CON), one (TMB1), or two (TMB2) long-acting TMBs. Feed intake was measured weekly, and camels were weighed monthly. Blood samples were collected from all camels on days 1, 30, 60, 90, 120, and 150 to obtain metabolic profiles. Zinc, selenium, copper, cobalt, and manganese concentrations were determined in the diet, serum, and liver. In comparison with controls, giving camels one TMB increased the average daily gain (14.38%; P < 0.04) and feed efficiency (13.68%; P < 0.01). Additionally, the serum and liver concentrations of zinc, copper, selenium, cobalt, and manganese were greater (P < 0.01) in camels in the TMB2 group. These data indicate that TMB supplementation has positive effects on the growth performance and trace mineral profiles of camels. Different levels, sources, and synergistic combinations of trace minerals can be used in further studies to elucidate their abilities to increase productive variables as well as their availability and cost to the camel industry.
Fast solar radiation pressure modelling with ray tracing and multiple reflections
NASA Astrophysics Data System (ADS)
Li, Zhen; Ziebart, Marek; Bhattarai, Santosh; Harrison, David; Grey, Stuart
2018-05-01
Physics based SRP (Solar Radiation Pressure) models using ray tracing methods are powerful tools when modelling the forces on complex real world space vehicles. Currently high resolution (1 mm) ray tracing with secondary intersections is done on high performance computers at UCL (University College London). This study introduces the BVH (Bounding Volume Hierarchy) into the ray tracing approach for physics based SRP modelling and makes it possible to run high resolution analysis on personal computers. The ray tracer is both general and efficient enough to cope with the complex shape of satellites and multiple reflections (three or more, with no upper limit). In this study, the traditional ray tracing technique is introduced in the first place and then the BVH is integrated into the ray tracing. Four aspects of the ray tracer were tested for investigating the performance including runtime, accuracy, the effects of multiple reflections and the effects of pixel array resolution.Test results in runtime on GPS IIR and Galileo IOV (In Orbit Validation) satellites show that the BVH can make the force model computation 30-50 times faster. The ray tracer has an absolute accuracy of several nanonewtons by comparing the test results for spheres and planes with the analytical computations. The multiple reflection effects are investigated both in the intersection number and acceleration on GPS IIR, Galileo IOV and Sentinel-1 spacecraft. Considering the number of intersections, the 3rd reflection can capture 99.12 %, 99.14 % , and 91.34 % of the total reflections for GPS IIR, Galileo IOV satellite bus and the Sentinel-1 spacecraft respectively. In terms of the multiple reflection effects on the acceleration, the secondary reflection effect for Galileo IOV satellite and Sentinel-1 can reach 0.2 nm /s2 and 0.4 nm /s2 respectively. The error percentage in the accelerations magnitude results show that the 3rd reflection should be considered in order to make it less than 0.035 % . The pixel array resolution tests show that the dimensions of the components have to be considered when choosing the spacing of the pixel in order not to miss some components of the satellite in ray tracing. This paper presents the first systematic and quantitative study of the secondary and higher order intersection effects. It shows conclusively the effect is non-negligible for certain classes of misson.
Helioviewer.org: An Open-source Tool for Visualizing Solar Data
NASA Astrophysics Data System (ADS)
Hughitt, V. Keith; Ireland, J.; Schmiedel, P.; Dimitoglou, G.; Mueller, D.; Fleck, B.
2009-05-01
As the amount of solar data available to scientists continues to increase at faster and faster rates, it is important that there exist simple tools for navigating this data quickly with a minimal amount of effort. By combining heterogeneous solar physics datatypes such as full-disk images and coronagraphs, along with feature and event information, Helioviewer offers a simple and intuitive way to browse multiple datasets simultaneously. Images are stored in a repository using the JPEG 2000 format and tiled dynamically upon a client's request. By tiling images and serving only the portions of the image requested, it is possible for the client to work with very large images without having to fetch all of the data at once. Currently, Helioviewer enables users to browse the entire SOHO data archive, updated hourly, as well as data feature/event catalog data from eight different catalogs including active region, flare, coronal mass ejection, type II radio burst data. In addition to a focus on intercommunication with other virtual observatories and browsers (VSO, HEK, etc), Helioviewer will offer a number of externally-available application programming interfaces (APIs) to enable easy third party use, adoption and extension. Future functionality will include: support for additional data-sources including TRACE, SDO and STEREO, dynamic movie generation, a navigable timeline of recorded solar events, social annotation, and basic client-side image processing.
Trace Elements in Parenteral Nutrition: Considerations for the Prescribing Clinician
Jin, Jennifer; Mulesa, Leanne; Carrilero Rouillet, Mariana
2017-01-01
Trace elements (TEs) are an essential component of parenteral nutrition (PN). Over the last few decades, there has been increased experience with PN, and with this knowledge more information about the management of trace elements has become available. There is increasing awareness of the effects of deficiencies and toxicities of certain trace elements. Despite this heightened awareness, much is still unknown in terms of trace element monitoring, the accuracy of different assays, and current TE contamination of solutions. The supplementation of TEs is a complex and important part of the PN prescription. Understanding the role of different disease states and the need for reduced or increased doses is essential. Given the heterogeneity of the PN patients, supplementation should be individualized. PMID:28452962
Trace Elements in Parenteral Nutrition: Considerations for the Prescribing Clinician.
Jin, Jennifer; Mulesa, Leanne; Carrilero Rouillet, Mariana
2017-04-28
Trace elements (TEs) are an essential component of parenteral nutrition (PN). Over the last few decades, there has been increased experience with PN, and with this knowledge more information about the management of trace elements has become available. There is increasing awareness of the effects of deficiencies and toxicities of certain trace elements. Despite this heightened awareness, much is still unknown in terms of trace element monitoring, the accuracy of different assays, and current TE contamination of solutions. The supplementation of TEs is a complex and important part of the PN prescription. Understanding the role of different disease states and the need for reduced or increased doses is essential. Given the heterogeneity of the PN patients, supplementation should be individualized.
ERIC Educational Resources Information Center
Takimoto, Masahiro
2014-01-01
The present study examined the effects of two types of input-based approaches--combination of pragmalinguistics- and sociopragmatics-focused instruction (CI) and sociopragmatics-focused instruction (SI) on learners' recognizing and producing English request hedges. 45 Japanese learners of English participated in the study. Treatment group…
ERIC Educational Resources Information Center
Ali, Emad
2009-01-01
The Picture Exchange Communication System (PECS) is an augmentative and alternative communication program (Frost & Bondy, 2002). Although PECS has been effectively used to teach functional requesting skills for children with autism, mental retardation, visual impairment, and physical disabilities (e.g., Anderson, Moore, & Bourne, 2007; Chambers &…
Assessing the role of contact tracing in a suspected H7N2 influenza A outbreak in humans in Wales
2010-01-01
Background The detailed analysis of an outbreak database has been undertaken to examine the role of contact tracing in controlling an outbreak of possible avian influenza in humans. The outbreak, initiating from the purchase of infected domestic poultry, occurred in North Wales during May and June 2007. During this outbreak, extensive contact tracing was carried out. Following contact tracing, cases and contacts believed to be at risk of infection were given treatment/prophylaxis. Methods We analyse the database of cases and their contacts identified for the purposes of contact tracing in relation to both the contact tracing burden and effectiveness. We investigate the distribution of numbers of contacts identified, and use network structure to explore the speed with which treatment/prophylaxis was made available and to estimate the risk of transmission in different settings. Results Fourteen cases of suspected H7N2 influenza A in humans were associated with a confirmed outbreak among poultry in May-June 2007. The contact tracing dataset consisted of 254 individuals (cases and contacts, of both poultry and humans) who were linked through a network of social contacts. Of these, 102 individuals were given treatment or prophylaxis. Considerable differences between individuals' contact patterns were observed. Home and workplace encounters were more likely to result in transmission than encounters in other settings. After an initial delay, while the outbreak proceeded undetected, contact tracing rapidly caught up with the cases and was effective in reducing the time between onset of symptoms and treatment/prophylaxis. Conclusions Contact tracing was used to link together the individuals involved in this outbreak in a social network, allowing the identification of the most likely paths of transmission and the risks of different types of interactions to be assessed. The outbreak highlights the substantial time and cost involved in contact tracing, even for an outbreak affecting few individuals. However, when sufficient resources are available, contact tracing enables cases to be identified before they result in further transmission and thus possibly assists in preventing an outbreak of a novel virus. PMID:20509927
Assessing the role of contact tracing in a suspected H7N2 influenza A outbreak in humans in Wales.
Eames, Ken T D; Webb, Cerian; Thomas, Kathrin; Smith, Josie; Salmon, Roland; Temple, J Mark F
2010-05-28
The detailed analysis of an outbreak database has been undertaken to examine the role of contact tracing in controlling an outbreak of possible avian influenza in humans. The outbreak, initiating from the purchase of infected domestic poultry, occurred in North Wales during May and June 2007. During this outbreak, extensive contact tracing was carried out. Following contact tracing, cases and contacts believed to be at risk of infection were given treatment/prophylaxis. We analyse the database of cases and their contacts identified for the purposes of contact tracing in relation to both the contact tracing burden and effectiveness. We investigate the distribution of numbers of contacts identified, and use network structure to explore the speed with which treatment/prophylaxis was made available and to estimate the risk of transmission in different settings. Fourteen cases of suspected H7N2 influenza A in humans were associated with a confirmed outbreak among poultry in May-June 2007. The contact tracing dataset consisted of 254 individuals (cases and contacts, of both poultry and humans) who were linked through a network of social contacts. Of these, 102 individuals were given treatment or prophylaxis. Considerable differences between individuals' contact patterns were observed. Home and workplace encounters were more likely to result in transmission than encounters in other settings. After an initial delay, while the outbreak proceeded undetected, contact tracing rapidly caught up with the cases and was effective in reducing the time between onset of symptoms and treatment/prophylaxis. Contact tracing was used to link together the individuals involved in this outbreak in a social network, allowing the identification of the most likely paths of transmission and the risks of different types of interactions to be assessed. The outbreak highlights the substantial time and cost involved in contact tracing, even for an outbreak affecting few individuals. However, when sufficient resources are available, contact tracing enables cases to be identified before they result in further transmission and thus possibly assists in preventing an outbreak of a novel virus.
Nürnberg, Daniela; Grüters, Annette; Führer-Sakel, Dagmar; Krude, Heiko; Köhrle, Josef; Schöneberg, Torsten; Biebermann, Heike
2011-01-01
Trace amine-associated receptors (TAAR) are rhodopsin-like G-protein-coupled receptors (GPCR). TAAR are involved in modulation of neuronal, cardiac and vascular functions and they are potentially linked with neurological disorders like schizophrenia and Parkinson's disease. Subtype TAAR1, the best characterized TAAR so far, is promiscuous for a wide set of ligands and is activated by trace amines tyramine (TYR), phenylethylamine (PEA), octopamine (OA), but also by thyronamines, dopamine, and psycho-active drugs. Unfortunately, effects of trace amines on signaling of the two homologous β-adrenergic receptors 1 (ADRB1) and 2 (ADRB2) have not been clarified yet in detail. We, therefore, tested TAAR1 agonists TYR, PEA and OA regarding their effects on ADRB1/2 signaling by co-stimulation studies. Surprisingly, trace amines TYR and PEA are partial allosteric antagonists at ADRB1/2, whereas OA is a partial orthosteric ADRB2-antagonist and ADRB1-agonist. To specify molecular reasons for TAAR1 ligand promiscuity and for observed differences in signaling effects on particular aminergic receptors we compared TAAR, tyramine (TAR) octopamine (OAR), ADRB1/2 and dopamine receptors at the structural level. We found especially for TAAR1 that the remarkable ligand promiscuity is likely based on high amino acid similarity in the ligand-binding region compared with further aminergic receptors. On the other hand few TAAR specific properties in the ligand-binding site might determine differences in ligand-induced effects compared to ADRB1/2. Taken together, this study points to molecular details of TAAR1-ligand promiscuity and identified specific trace amines as allosteric or orthosteric ligands of particular β-adrenergic receptor subtypes. PMID:22073124
42 CFR 495.362 - Retroactive approval of FFP with an effective date of February 18, 2009.
Code of Federal Regulations, 2010 CFR
2010-10-01
... HEALTH RECORD TECHNOLOGY INCENTIVE PROGRAM Requirements Specific to the Medicaid Program § 495.362... payments to providers, a State may request consideration of FFP by recorded request in a HIT advance...
42 CFR 90.5 - Acting on requests.
Code of Federal Regulations, 2011 CFR
2011-10-01
... STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES ADMINISTRATIVE FUNCTIONS, PRACTICES, AND... potential for further human exposure; (4) The recommendations of other governmental agencies; and (5) The... health assessments and health effects studies. (b) Where appropriate, ATSDR will request information from...
42 CFR 90.5 - Acting on requests.
Code of Federal Regulations, 2010 CFR
2010-10-01
... STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES ADMINISTRATIVE FUNCTIONS, PRACTICES, AND... potential for further human exposure; (4) The recommendations of other governmental agencies; and (5) The... health assessments and health effects studies. (b) Where appropriate, ATSDR will request information from...
Kiseleva, N M; Novoseletskaya, A V; Voevodina, Ye B; Kozlov, I G; Inozemtsev, A N
2012-12-01
Apart from restoration of disordered immunological parameters, tactivin and derinat exhibit a pronounced effect on the higher integrative functions of the brain. Experiments on Wistar rats have shown that these drugs accelerated conditioning of food and defense responses. New methods for quantitative evaluation of memory trace consolidation are proposed.
How Certain Trace Elements Behave.
ERIC Educational Resources Information Center
Zingaro, Ralph A.
1979-01-01
Fluorine, selenium, tin, and arsenic are among the trace elements occurring in the environment which are considered. Emphasis is given to developing a qualitative survey of the extent and kinds of metal transformations and their resultant effects. (CS)
ERIC Educational Resources Information Center
Pettyjohn, Wayne A.
1972-01-01
Summarizes the effects of arsenic, lead, zinc, mercury, and cadmium on human health, indicates the sources of the elements in water, and considers the possibility of students in high schools analyzing water for trace amounts of the elements. (AL)
The trace anomaly and dynamical vacuum energy in cosmology
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mottola, Emil
2010-04-30
The trace anomaly of conformal matter implies the existence of massless scalar poles in physical amplitudes involving the stress-energy tensor. These poles may be described by a local effective action with massless scalar fields, which couple to classical sources, contribute to gravitational scattering processes, and can have long range gravitational effects at macroscopic scales. In an effective field theory approach, the effective action of the anomaly is an infrared relevant term that should be added to the Einstein-Hilbert action of classical General Relativity to take account of macroscopic quantum effects. The additional scalar degrees of freedom contained in this effectivemore » action may be understood as responsible for both the Casimir effect in flat spacetime and large quantum backreaction effects at the horizon scale of cosmological spacetimes. These effects of the trace anomaly imply that the cosmological vacuum energy is dynamical, and its value depends on macroscopic boundary conditions at the cosmological horizon scale, rather than sensitivity to the extreme ultraviolet Planck scale.« less
Bing, Haijian; Wu, Yanhong; Zhou, Jun; Li, Rui; Luo, Ji; Yu, Dong
2016-01-01
Trace metals adsorbed onto fine particles can be transported long distances and ultimately deposited in Polar Regions via the cold condensation effect. This study indicated the possible sources of silver (Ag), cadmium (Cd), copper (Cu), lead (Pb), antimony (Sb) and zinc (Zn) in soils on the eastern slope of Mt. Gongga, eastern Tibetan Plateau, and deciphered the effects of vegetation and mountain cold condensation on their distributions with elevation. The metal concentrations in the soils were comparable to other mountains worldwide except the remarkably high concentrations of Cd. Trace metals with high enrichment in the soils were influenced from anthropogenic contributions. Spatially, the concentrations of Cu and Zn in the surface horizons decreased from 2000 to 3700 m a.s.l., and then increased with elevation, whereas other metals were notably enriched in the mid-elevation area (approximately 3000 m a.s.l.). After normalization for soil organic carbon, high concentrations of Cd, Pb, Sb and Zn were observed above the timberline. Our results indicated the importance of vegetation in trace metal accumulation in an alpine ecosystem and highlighted the mountain cold trapping effect on trace metal deposition sourced from long-range atmospheric transport. PMID:27052807
Tudor, G Samuel J; Harden, Susan V; Thomas, Simon J
2014-03-01
Dose differences from those planned can occur due to the respiratory interplay effect on helical tomotherapy. The authors present a technique to calculate single-fraction doses in three-dimensions resulting from craniocaudal motion applied to a patient CT set. The technique is applied to phantom and patient plans using patient respiratory traces. An additional purpose of the work is to determine the contribution toward the interplay effect of different components of the respiratory trace. MATLAB code used to calculate doses to a CT dataset from a helical tomotherapy plan has been modified to permit craniocaudal motion and improved temporal resolution. Real patient traces from seven patients were applied to ten phantom plans of differing field width, modulation factor, pitch and fraction dose, and simulations made with peak-to-peak amplitudes ranging from 0 to 2.5 cm. PTV voxels near the superior or inferior limits of the PTV are excluded from the analysis. The maximum dose discrepancy compared with the static case recorded along with the proportion of voxels receiving more than 10% and 20% different from prescription dose. The analysis was repeated with the baseline variation of the respiratory trace removed, leaving the cyclic component of motion only. Radiochromic film was used on one plan-trace combination and compared with the software simulation. For one case, filtered traces were generated and used in simulations which consisted only of frequencies near to particular characteristic frequencies of the treatment delivery. Intraslice standard deviation of dose differences was used to identify potential MLC interplay, which was confirmed using nonmodulated simulations. Software calculations were also conducted for four realistic patient plans and modeling movement of a patient CT set with amplitudes informed by the observed motion of the GTV on 4DCT. The maximum magnitude of dose difference to a PTV voxel due to the interplay effect within a particular plan-trace combination for peak-to-peak amplitudes of up to 2.5 cm ranged from 4.5% to 51.6% (mean: 23.8%) of the dose delivered in the absence of respiratory motion. For cyclic motion only, the maximum dose differences in each combination ranged from 2.1% to 26.2% (mean: 9.2%). There is reasonable correspondence between an example of the phantom plan simulations and radiochromic film measurement. The filtered trace simulations revealed that frequencies close to the characteristic frequency of the jaw motion across the target were found to generate greater interplay effect than frequencies close to the gantry frequency or MLC motion. There was evidence of interplay between respiratory motion and MLC modulation, but this is small compared with the interplay between respiratory motion and jaw motion. For patient-plan simulations, dose discrepancies are seen of up to 9.0% for a patient with 0.3 cm peak-to-peak respiratory amplitude and up to 17.7% for a patient with 0.9 cm peak-to-peak amplitude. These values reduced to 1.3% and 6.5%, respectively, when only cyclic motion was considered. Software has been developed to simulate craniocaudal respiratory motion in phantom and patient plans using real patient respiratory traces. Decomposition of the traces into baseline andcyclic components reveals that the large majority of the interplay effect seen with the full trace is due to baseline variation during treatment.
NASA Technical Reports Server (NTRS)
Brandon, A. D.; Ferdous, J.; Peslier, A. H.
2017-01-01
The issue of whether crustal contamination has affected the lithophile trace element budget of shergottites has been a point of contention for decades. The evaluation has focused on the enriched shergottite compositions as an outcome of crustal contamination of mantle-derived parent magmas or, alternatively, the compositions of these stones reflect an incompatible trace element (ITE) enriched mantle source.
Pan, Yunyu; Koopmans, Gerwin F; Bonten, Luc T C; Song, Jing; Luo, Yongming; Temminghoff, Erwin J M; Comans, Rob N J
2016-12-01
Alternating flooding and drainage conditions have a strong influence on redox chemistry and the solubility of trace metals in paddy soils. However, current knowledge of how the effects of water management on trace metal solubility are linked to trace metal uptake by rice plants over time is still limited. Here, a field-contaminated paddy soil was subjected to two flooding and drainage cycles in a pot experiment with two rice plant cultivars, exhibiting either high or low Cd accumulation characteristics. Flooding led to a strong vertical gradient in the redox potential (Eh). The pH and Mn, Fe, and dissolved organic carbon concentrations increased with decreasing Eh and vice versa. During flooding, trace metal solubility decreased markedly, probably due to sulfide mineral precipitation. Despite its low solubility, the Cd content in rice grains exceeded the food quality standards for both cultivars. Trace metal contents in different rice plant tissues (roots, stem, and leaves) increased at a constant rate during the first flooding and drainage cycle but decreased after reaching a maximum during the second cycle. As such, the high temporal variability in trace metal solubility was not reflected in trace metal uptake by rice plants over time. This might be due to the presence of aerobic conditions and a consequent higher trace metal solubility near the root surface, even during flooding. Trace metal solubility in the rhizosphere should be considered when linking water management to trace metal uptake by rice over time.
Double Dissociation of Amygdala and Hippocampal Contributions to Trace and Delay Fear Conditioning
Raybuck, Jonathan D.; Lattal, K. Matthew
2011-01-01
A key finding in studies of the neurobiology of learning memory is that the amygdala is critically involved in Pavlovian fear conditioning. This is well established in delay-cued and contextual fear conditioning; however, surprisingly little is known of the role of the amygdala in trace conditioning. Trace fear conditioning, in which the CS and US are separated in time by a trace interval, requires the hippocampus and prefrontal cortex. It is possible that recruitment of cortical structures by trace conditioning alters the role of the amygdala compared to delay fear conditioning, where the CS and US overlap. To investigate this, we inactivated the amygdala of male C57BL/6 mice with GABA A agonist muscimol prior to 2-pairing trace or delay fear conditioning. Amygdala inactivation produced deficits in contextual and delay conditioning, but had no effect on trace conditioning. As controls, we demonstrate that dorsal hippocampal inactivation produced deficits in trace and contextual, but not delay fear conditioning. Further, pre- and post-training amygdala inactivation disrupted the contextual but the not cued component of trace conditioning, as did muscimol infusion prior to 1- or 4-pairing trace conditioning. These findings demonstrate that insertion of a temporal gap between the CS and US can generate amygdala-independent fear conditioning. We discuss the implications of this surprising finding for current models of the neural circuitry involved in fear conditioning. PMID:21283812
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2011-10-26
... Division Record Information Dissemination Section (RIDS) will be submitting the following information... collection: Records Management Division/ Record Information Dissemination Section, Federal Bureau of... requesters etc). Abstract: The Record/Information Dissemination Section (RIDS) effectively plans, develops...
Investigation of Chemical Processes Involving Laser-generated Nanoenergetic Materials
2010-02-01
nanoparticle formation, nanoenergetic materials, laser ablation, plasma chemistry , optical emission 16. SECURITY CLASSIFICATION OF: 17...alloys with known trace metal concentrations. In addition to observing the effect of trace metals on the plasma chemistry , commercially available
Wall, David M; Allen, Eoin; Straccialini, Barbara; O'Kiely, Padraig; Murphy, Jerry D
2014-11-01
This study investigated the effect of trace element addition to mono-digestion of grass silage at high organic loading rates. Two continuous reactors were compared. The first mono-digested grass silage whilst the second operated in co-digestion, 80% grass silage with 20% dairy slurry (VS basis). The reactors were run for 65weeks with a further 5weeks taken for trace element supplementation for the mono-digestion of grass silage. The co-digestion reactor reported a higher biomethane efficiency (1.01) than mono-digestion (0.90) at an OLR of 4.0kgVSm(-3)d(-1) prior to addition of trace elements. Addition of cobalt, iron and nickel, led to an increase in the SMY in mono-digestion of grass silage by 12% to 404LCH4kg(-1)VS and attained a biomethane efficiency of 1.01. Copyright © 2014 Elsevier Ltd. All rights reserved.
Lee, Annisa Lai
2009-06-01
This study tracks the changes of the effects of 4 information sources for direct-to-consumer drug advertising on patients' requests for prescription drugs from physicians since the inception of the "Guidance for Industry about Consumer-directed Broadcast Advertisements." The Guidance advises pharmaceuticals to use four information sources for consumers to seek further information to supplement broadcast drug advertisements: small-print information, the Internet, a toll-free number, and health-care providers (nurses, doctors, and pharmacists). Logistic models were created by using survey data collected by the Food and Drug Administration in 1999 and 2002. Results show that throughout the years, health-care providers remain the most used and strongest means associated with patients' direct requests for nonspecific and specific prescription drugs from doctors. The small-print information source gains power and changes from an indirect means associated with patients' discussing drugs with health-care providers to a direct means associated with patients' asking about nonspecific and specific drugs from their doctors. The Internet is not directly related to drug requests, but the effect of its association with patients seeking information from health-care providers grew 11-fold over the course of the study. The toll-free number lost its power altogether for both direct request for a prescription drug and further discussion with health-care providers. Patient demographics will be considered for specific policy implications.
Dredging-related mobilisation of trace metals: a case study in The Netherlands.
van den Berg, G A; Meijers, G G; van der Heijdt, L M; Zwolsman, J J
2001-06-01
Mobilisation of contaminants is an important issue in environmental risk assessment of dredging projects. This study has aimed at identifying the effects of dredging on mobilisation of trace metals (Zn, Cu, Cd and Pb). The intensities and time scales of trace metal mobilisation were investigated during an experimental dredging project conducted under field conditions. The loss of contaminated dredge spoil is mainly reflected by increasing levels of trace metals in the suspended matter, dissolved trace metal concentrations in the water column are not significantly influenced by the dredging activities. This indicates a strong binding mechanism of trace metals to the solid phase or a fast redistribution over sorptive phases in response to oxidation of e.g. trace metal sulphides. Given the differences in levels of reactive phases (Mn, Fe, sulphides and organic matter) between the riverine suspended matter and the sediments, changes in the levels of these parameters in the suspended matter upon dredging may give information on the processes influencing the behaviour of trace metals and on the potential loss of sediment during dredging operations. Therefore, we recommend to routinely measure these parameters in studies on contaminant behaviour related to dredging activities.
The influence of carbon, sulfur, and silicon on trace element partitioning in iron alloys
NASA Astrophysics Data System (ADS)
Han, J.; Van Orman, J. A.; Crispin, K. L.; Ash, R. D.
2014-12-01
Non-metallic light elements are important constituents of planetary cores and have a strong influence on the partitioning behavior of trace elements. Planetary cores may contain a wide range of non-metallic light elements, including H, N, S, P, Si, and C. Under highly reducing conditions, such as those that are thought to have pertained during the formation of Mercury's core, Si and C, in addition to sulfur, may be particularly important constituents. Each of these elements may strongly effect and have a different impact on the partitioning behavior of trace elements but their combined effects on trace element partitioning have not been quantified. We investigated the partitioning behavior of more than 25 siderophile trace elements within the Fe-S-C-Si system with varying concentrations of C, S, and Si. The experiments were performed under pressures varying from 1 atm to 2 GPa and temperatures ranging from 1200˚C to 1450˚C. All experiments produced immiscible liquids, one enriched in Si and C, and the other predominantly FeS. We found some highly siderophile elements including Os, Ru, Ir, and Re are much more enriched in Fe-Si-C phase than in Fe-S phase, whereas other trace elements like V, Co, Ag, Hf, and Pb are enriched in S-rich phase. However, not all the trace elements enriched in Fe-Si-C phase are repelled by sulfur. Elements like Re and Ru could have different partitioning trends if sulfur concentration in S-rich phase rises. The partitioning behavior of these trace elements could enhance our understanding of the differentiation of Mercury's core under oxygen-poor conditions.
NASA Astrophysics Data System (ADS)
Iida, Michihira; Maeno, Tsuyoshi; Fujiwara, Osamu
It is well known that electromagnetic disturbances in vehicle-mounted radios are mainly caused by conducted noise currents flowing through wiring-harnesses from vehicle-mounted printed circuit boards (PCBs) with common ground patterns containing slits. To suppress the noise currents outflow from PCBs of these kinds, we previously measured noise currents outflow from simple two-layer PCBs having two parallel signal traces and different ground patterns with/without slits to reveal that making slits with open ends on the ground patterns in parallel with the traces can reduce the conducted noise currents. In the present study, with FDTD simulation, we investigated reduction effects of ground patterns size on the FM-band cross-talk noise levels between two parallel signal traces, by using four types of simple PCB models having different ground patterns formed in different numbers but containing the same planar dimension slits parallel to the traces, in addition to two types of PCB models with different ground patterns divided into two parts parallel to the traces. As a result, we found that the cross-talk noise currents for the above six types of PCBs decrease by 6.9-8.5dB compared to the PCB which has a plain ground with no slits. From this study, we got the finding that the contributing factor for the above mentioned cross-talk reduction relies on the reduction of mutual inductance between the two parallel traces. In addition, in case of this study, it is interesting to note that the noise currents outflow from PCBs can rather be suppressed when the size of the return ground of each signal trace is small.
NASA Astrophysics Data System (ADS)
Faucher, Giulia; Hoffmann, Linn; Bach, Lennart T.; Bottini, Cinzia; Erba, Elisabetta; Riebesell, Ulf
2017-07-01
The Cretaceous ocean witnessed intervals of profound perturbations such as volcanic input of large amounts of CO2, anoxia, eutrophication and introduction of biologically relevant metals. Some of these extreme events were characterized by size reduction and/or morphological changes of a few calcareous nannofossil species. The correspondence between intervals of high trace metal concentrations and coccolith dwarfism suggests a negative effect of these elements on nannoplankton biocalcification processes in past oceans. In order to test this hypothesis, we explored the potential effect of a mixture of trace metals on growth and morphology of four living coccolithophore species, namely Emiliania huxleyi, Gephyrocapsa oceanica, Pleurochrysis carterae and Coccolithus pelagicus. The phylogenetic history of coccolithophores shows that the selected living species are linked to Mesozoic species showing dwarfism under excess metal concentrations. The trace metals tested were chosen to simulate the environmental stress identified in the geological record and upon known trace metal interactions with living coccolithophore algae.Our laboratory experiments demonstrated that elevated trace metal concentrations, similarly to the fossil record, affect coccolithophore algae size and/or weight. Smaller coccoliths were detected in E. huxleyi and C. pelagicus, while coccoliths of G. oceanica showed a decrease in size only at the highest trace metal concentrations. P. carterae coccolith size was unresponsive to changing trace metal concentrations. These differences among species allow discriminating the most- (P. carterae), intermediate- (E. huxleyi and G. oceanica) and least-tolerant (C. pelagicus) taxa. The fossil record and the experimental results converge on a selective response of coccolithophores to metal availability.These species-specific differences must be considered before morphological features of coccoliths are used to reconstruct paleo-chemical conditions.
Hattingh, Hendrika Laetitia; Varsani, Janki; Kachouei, Leila Ataei; Parsons, Richard
2016-08-30
A community pharmacy real-time electronic recording program, ProjectSTOP, enables Australian community pharmacists to verify pseudoephedrine requests. In Western Australia the program was available for voluntary use from April 2007 and became mandatory November 2010. This case study explores the effectiveness of the program by reviewing the total requests for pseudoephedrine products, and the proportion of requests which were classified as 'denied sales' before and after mandatory implementation. Seasonal and annual trends in these measures are also evaluated. ProjectSTOP data recordings for Western Australia pharmacies between 1 December 2007 and 28 February 2014 were analysed. Data included a de-identified pharmacy number and date of each pseudoephedrine product request. The total number of requests and sale classification (allowed, denied, safety, or not recorded) were calculated for each month/pharmacy. The potential influence of mandatory reporting using ProjectSTOP was investigated using a Regression Discontinuity Design. Correlations between sales from the same pharmacy were taken into account by classifying the pharmacy number as a random effect. The main effects of year (continuous variable), and season (categorical variable) were also included in the model. There was a small but steady decline in the total requests for pseudoephedrine per month per 100,000 population (per pharmacy) from the time of mandatory reporting. The number of denied sales showed a steady increase up until mandatory reporting, after which it showed a significant decline over time. Total sales were heavily influenced by season, as expected (highest in winter, least in summer). The seasonal pattern was less pronounced for denied sales, which were highest in winter and similar across other seasons. The pattern over time for safety sales was similar to that for denied sales, with a clear change occurring around the time of mandatory reporting. Results indicate a decrease in pseudoephedrine product requests in Western Australia community pharmacies. Findings suggest ProjectSTOP has been successful in addressing suspicious sales and potential diversion however ongoing data review is recommended.
ERIC Educational Resources Information Center
Olive, Melissa L.; de la Cruz, Berenice; Davis, Tonya N.; Chan, Jeffrey M.; Lang, Russell B.; O'Reilly, Mark F.; Dickson, Sarah M.
2007-01-01
The purpose of this study was to evaluate the effects of enhanced milieu teaching when combined with a voice output communication aid on the requesting skills of three children with autism. The research design was a multiple probe across participants. All sessions were conducted during 5-min play sessions in the child's classroom. All three…
Workload Characterization and Performance Implications of Large-Scale Blog Servers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jeon, Myeongjae; Kim, Youngjae; Hwang, Jeaho
With the ever-increasing popularity of social network services (SNSs), an understanding of the characteristics of these services and their effects on the behavior of their host servers is critical. However, there has been a lack of research on the workload characterization of servers running SNS applications such as blog services. To fill this void, we empirically characterized real-world web server logs collected from one of the largest South Korean blog hosting sites for 12 consecutive days. The logs consist of more than 96 million HTTP requests and 4.7 TB of network traffic. Our analysis reveals the followings: (i) The transfermore » size of non-multimedia files and blog articles can be modeled using a truncated Pareto distribution and a log-normal distribution, respectively; (ii) User access for blog articles does not show temporal locality, but is strongly biased towards those posted with image or audio files. We additionally discuss the potential performance improvement through clustering of small files on a blog page into contiguous disk blocks, which benefits from the observed file access patterns. Trace-driven simulations show that, on average, the suggested approach achieves 60.6% better system throughput and reduces the processing time for file access by 30.8% compared to the best performance of the Ext4 file system.« less
The role of laboratory in ensuring appropriate test requests.
Ferraro, Simona; Panteghini, Mauro
2017-07-01
This review highlights the role of laboratory professionals and the strategies to be promoted in strict cooperation with clinicians for auditing, monitoring and improving the appropriateness of test request. The introduction of local pathways and care maps in agreement with international and national guidelines as well as the implementation of reflex testing and algorithms have a central role in guiding test request and in correcting the overuse/misuse of tests. Furthermore, removing obsolete tests from laboratory menu and vetting of restricted tests is recommended to increase cost-effectiveness. This saves costs and permits to introduce new biomarkers with increased diagnostic accuracy with a better impact on patient outcome. An additional issue is concerning the periodicity of (re)testing, accounting that only a minority of tests may be ordered as often as necessary. In the majority of cases, a minimum retesting interval should be introduced. The availability of effective computerised order entry systems is relevant in ensuring appropriate test requests and in providing an aid by automated rules that may stop inappropriate requests before they reach the laboratory. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
Evaluating a restrictive formulary system by assessing nonformulary-drug requests.
Green, J A; Chawla, A K; Fong, P A
1985-07-01
Nonformulary-drug requests were used to evaluate a restrictive formulary system in a large university hospital, and a telephone survey of eight similar hospitals was conducted to assess the restrictiveness of their formulary systems. Nonformulary-drug requests were evaluated by two drug information pharmacists over a 12-month period (January-December 1984) to assess the frequency with which nonformulary items were ordered, the costs associated with the procurement of nonformulary drug products, and the rationales given by physicians when ordering nonformulary products. Of all nonformulary requests, 65% were for drugs previously evaluated by the pharmacy and therapeutics committee and denied admission to the formulary. A cost savings of $1887 would have resulted if formulary alternates had been used instead of nonformulary products. Excluding 22% of nonformulary items that were requested for the continuation of preadmission drug therapy, only 13% of the rationales for the remaining requests were appropriate. Although the eight other hospitals surveyed said they had restrictive formularies, all had frequent requests and procedures for procuring nonformulary items and some formularies included most available drugs. The formulary system at the study hospital was considered restrictive, but procedures for nonformulary-drug requests limited the effectiveness of the system. If any benefit is to result from formulary systems, hospitals must strengthen their enforcement of formulary restrictions.
Stoney, David A; Stoney, Paul L
2015-08-01
An effective trace evidence capability is defined as one that exploits all useful particle types, chooses appropriate technologies to do so, and directly integrates the findings with case-specific problems. Limitations of current approaches inhibit the attainment of an effective capability and it has been strongly argued that a new approach to trace evidence analysis is essential. A hypothetical case example is presented to illustrate and analyze how forensic particle analysis can be used as a powerful practical tool in forensic investigations. The specifics in this example, including the casework investigation, laboratory analyses, and close professional interactions, provide focal points for subsequent analysis of how this outcome can be achieved. This leads to the specification of five key elements that are deemed necessary and sufficient for effective forensic particle analysis: (1) a dynamic forensic analytical approach, (2) concise and efficient protocols addressing particle combinations, (3) multidisciplinary capabilities of analysis and interpretation, (4) readily accessible external specialist resources, and (5) information integration and communication. A coordinating role, absent in current approaches to trace evidence analysis, is essential to achieving these elements. However, the level of expertise required for the coordinating role is readily attainable. Some additional laboratory protocols are also essential. However, none of these has greater staffing requirements than those routinely met by existing forensic trace evidence practitioners. The major challenges that remain are organizational acceptance, planning and implementation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
75 FR 9418 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-02
... OMB Review; Comment Request Title: Evaluation of Adolescent Pregnancy Prevention Approaches-- Baseline... part of the Evaluation of Adolescent Pregnancy Prevention Approaches (PPA). PPA is being undertaken to expand available evidence on effective ways to reduce teen pregnancy. The evaluation will document and...
78 FR 39296 - Proposed Information Collection Activity; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-01
... Information Collection Activity; Comment Request Proposed Projects Title: State Abstinence Education Program... accurate and effective abstinence-based plans responsive to their specific needs and inclusive of vulnerable populations. These plans must provide abstinence education, and at the option of the State, where...
7 CFR 400.309 - Requests for reconsideration.
Code of Federal Regulations, 2011 CFR
2011-01-01
... classification becomes effective. The request will be considered to have been made when received, in writing, by..., DEPARTMENT OF AGRICULTURE GENERAL ADMINISTRATIVE REGULATIONS Non-Standard Underwriting Classification System... be assigned a nonstandard classification under this subpart will be notified of and allowed not less...
7 CFR 400.309 - Requests for reconsideration.
Code of Federal Regulations, 2010 CFR
2010-01-01
... classification becomes effective. The request will be considered to have been made when received, in writing, by..., DEPARTMENT OF AGRICULTURE GENERAL ADMINISTRATIVE REGULATIONS Non-Standard Underwriting Classification System... be assigned a nonstandard classification under this subpart will be notified of and allowed not less...
75 FR 69473 - Agency Information Collection Activities: Submission for OMB Review; Comment Request
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2010-11-12
... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Submission for OMB Review; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION... effectiveness of the Public Vaults and its several exhibits in enhancing visitors' understanding that records...
Integrating Consumer Requests Into Community Organized Programs
ERIC Educational Resources Information Center
Brown, Sanford M.
1977-01-01
The environmental health administrative problem of reducing and/or eliminating individual complaints or requests by integrating them with the planned community environmental health program is discussed. Four parameters are detailed: problem assessment, priority establishment, activity sequencing and the evaluation of program effectiveness. (BT)
7 CFR 900.311 - Submittals or requests.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Conduct of Referenda To Determine Producer Approval of Milk Marketing Orders To Be Made Effective Pursuant to Agricultural Marketing Agreement Act of 1937, as Amended § 900.311 Submittals or requests... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing...
Qin, Yuan; Michalowski, Andreas; Weber, Rudolf; Yang, Sen; Graf, Thomas; Ni, Xiaowu
2012-11-19
Ray-tracing is the commonly used technique to calculate the absorption of light in laser deep-penetration welding or drilling. Since new lasers with high brilliance enable small capillaries with high aspect ratios, diffraction might become important. To examine the applicability of the ray-tracing method, we studied the total absorptance and the absorbed intensity of polarized beams in several capillary geometries. The ray-tracing results are compared with more sophisticated simulations based on physical optics. The comparison shows that the simple ray-tracing is applicable to calculate the total absorptance in triangular grooves and in conical capillaries but not in rectangular grooves. To calculate the distribution of the absorbed intensity ray-tracing fails due to the neglected interference, diffraction, and the effects of beam propagation in the capillaries with sub-wavelength diameter. If diffraction is avoided e.g. with beams smaller than the entrance pupil of the capillary or with very shallow capillaries, the distribution of the absorbed intensity calculated by ray-tracing corresponds to the local average of the interference pattern found by physical optics.
Predicting Individual Characteristics from Digital Traces on Social Media: A Meta-Analysis.
Settanni, Michele; Azucar, Danny; Marengo, Davide
2018-04-01
The increasing utilization of social media provides a vast and new source of user-generated ecological data (digital traces), which can be automatically collected for research purposes. The availability of these data sets, combined with the convergence between social and computer sciences, has led researchers to develop automated methods to extract digital traces from social media and use them to predict individual psychological characteristics and behaviors. In this article, we reviewed the literature on this topic and conducted a series of meta-analyses to determine the strength of associations between digital traces and specific individual characteristics; personality, psychological well-being, and intelligence. Potential moderator effects were analyzed with respect to type of social media platform, type of digital traces examined, and study quality. Our findings indicate that digital traces from social media can be studied to assess and predict theoretically distant psychosocial characteristics with remarkable accuracy. Analysis of moderators indicated that the collection of specific types of information (i.e., user demographics), and the inclusion of different types of digital traces, could help improve the accuracy of predictions.
PRESERVATION OF TRACE METALS IN WATER SAMPLES
Questions about trace metal preservation are resurfacing because the health effect risks associated with certain metals continue to drive the required reporting limits lower. Inductively coupled plasma-mass spectrometry was used in this study to analyze preservation of samples co...
An exploration of GPs' use of MRI: a critical incident study.
Robling, M; Kinnersley, P; Houston, H; Hourihan, M; Cohen, D; Hale, J
1998-06-01
Direct access to Magnetic Resonance Imaging (MRI) is becoming available to GPs in the UK, offering major benefits for the improved diagnosis and management of certain clinical conditions. Variations in usage of this service may be large, and effective locally produced guidelines are not currently available. The Department of General Practice is conducting a research programme to develop and evaluate methods to optimize MRI use by GPs. We aimed to describe the current use of MRI by GPs in South Glamorgan; to summarize their reasons for requesting MRI; and to produce criteria to assess the appropriateness of magnetic resonance (MR) scan requests. Using the critical incident technique, 25 GPs were interviewed about recent scans requested for patients with knee and lumbar spine complaints. A local panel of primary and secondary care doctors was convened to develop criteria for assessing MR scan requests. Sixty-two scan requests were discussed. Doctors' reasons for requesting MR scans were identified and classified. Reasons for requests included personal, contextual and biomedical variables. Fifteen patients (24%) were managed in primary care following MRI when otherwise they would have been referred. When referrals were made, GPs felt able to reinforce the request and occasionally to direct the patient somewhere more appropriate. The panel reviewed the interview data to produce objective criteria to assess scan requests. The criteria reflect the relative importance of non-biomedical variables in the decision to request MRI. The study identified those reasons which are important to GPs when requesting MR scans and the impact of this new technology upon patient management. Interview data have been used to inform locally developed consensus criteria, which will be made available as practice guidelines as the research programme progresses.
Diop, Cheikh; Dewaelé, Dorothée; Cazier, Fabrice; Diouf, Amadou; Ouddane, Baghdad
2015-11-01
Trace metals have the potential to associate with sediments that have been recognised as significant source of contamination for the benthic environment. The current study aims assessing the trace metals contamination level in sediments from Dakar coast and Saint Louis estuary, and to examine their bioavailability to predict potential toxicity of sediments. Surface sediment samples were collected between June 2012 and January 2013 in three sampling periods from eight stations. Trace metals were analysed using inductively coupled plasma-optical emission spectrometer. Geoaccumulation indexes (Igeo) showed strong pollution by Cd, Cr, Cu and Pb confirmed by enrichment factor (EF) suggesting that these metals derived from anthropogenic sources. Toxicity indexes exceeded one in several sites suggesting the potential effects on sediment-dwelling organisms, which may constitute a risk to populations' health. However, seasonal variability of metal bioavailability was noted, revealing the best period to monitor metal contamination. From an ecotoxicological point of view, concentrations of Cd, Cr, Cu and Pb were above the effects range low threshold limit of the sediment quality guidelines for adverse biological effects. In addition, with Pb concentrations above the effect range medium values in some sites, biological effects may occur. Copyright © 2014 Elsevier Ltd. All rights reserved.
Trace elements as paradigms of developmental neurotoxicants: lead, methylmercury and arsenic
Grandjean, Philippe; Herz, Katherine T.
2014-01-01
Trace elements have contributed unique insights into developmental neurotoxicity and serve as paradigms for such adverse effects. Many trace elements are retained in the body for long periods and can be easily measured to assess exposure by inexpensive analytical methods that became available several decades ago so that past and cumulated exposures could be easily characterized through analysis of biological samples, e.g. blood and urine. The first compelling evidence resulted from unfortunate poisoning events that allowed scrutiny of long-term outcomes of acute exposures that occurred during early development. Pursuant to this documentation, prospective studies of children's cohorts that applied sensitive neurobehavioral methods supported the notion that the brain is uniquely vulnerable to toxic damage during early development. Lead, methylmercury, and arsenic thereby serve as paradigm neurotoxicants that provide a reference for other substances that may have similar adverse effects. Less evidence is available on manganese, fluoride, and cadmium, but experience from the former trace elements suggest that, with time, adverse effects are likely to be documented at exposures previously thought to be low and safe. PMID:25175507
Trace elements as paradigms of developmental neurotoxicants: Lead, methylmercury and arsenic.
Grandjean, Philippe; Herz, Katherine T
2015-01-01
Trace elements have contributed unique insights into developmental neurotoxicity and serve as paradigms for such adverse effects. Many trace elements are retained in the body for long periods and can be easily measured to assess exposure by inexpensive analytical methods that became available several decades ago so that past and cumulated exposures could be easily characterized through analysis of biological samples, e.g. blood and urine. The first compelling evidence resulted from unfortunate poisoning events that allowed scrutiny of long-term outcomes of acute exposures that occurred during early development. Pursuant to this documentation, prospective studies of children's cohorts that applied sensitive neurobehavioral methods supported the notion that the brain is uniquely vulnerable to toxic damage during early development. Lead, methylmercury, and arsenic thereby serve as paradigm neurotoxicants that provide a reference for other substances that may have similar adverse effects. Less evidence is available on manganese, fluoride, and cadmium, but experience from the former trace elements suggest that, with time, adverse effects are likely to be documented at exposures previously thought to be low and safe. Copyright © 2014 Elsevier GmbH. All rights reserved.
NASA Technical Reports Server (NTRS)
Kornacki, Alan S.; Fegley, Bruce, Jr.
1986-01-01
The relative volatilities of lithophile refractory trace elements (LRTE) were determined using calculated 50-percent condensation temperatures. Then, the refractory trace-element abundances were measured in about 100 Allende inclusions. The abundance patterns found in Allende Ca,Al-rich inclusions (CAIs) and ultrarefractory inclusions were used to empirically modify the calculated LRTE volatility sequence. In addition, the importance of crystal-chemical effects, diffusion constraints, and grain transport for the origin of the trace-element chemistry of Allende CAIs (which have important implications for chemical and physical processes in the solar nebula) is discussed.
Cause and Effects of Fluorocarbon Degradation in Electronics and Opto-Electronic Systems
NASA Technical Reports Server (NTRS)
Predmore, Roamer E.; Canham, John S.
2002-01-01
Trace degradation of fluorocarbon or halocarbon materials must be addressed in their application in sensitive systems. As the dimensions and/or tolerances of components in a system decrease, the sensitivity of the system to trace fluorocarbon or halocarbon degradation products increases. Trace quantities of highly reactive degradation products from fluorocarbons have caused a number of failures of flight hardware. It is of utmost importance that the risk of system failure, resulting from trace amounts of reactive fluorocarbon degradation products be addressed in designs containing fluorocarbon or halocarbon materials. Thermal, electrical, and mechanical energy input into the system can multiply the risk of failure.
Cai, Yafan; Wang, Jungang; Zhao, Yubin; Zhao, Xiaoling; Zheng, Zehui; Wen, Boting; Cui, Zongjun; Wang, Xiaofen
2018-09-01
Trace elements were commonly used as additives to facilitate anaerobic digestion. However, their addition is often blind because of the complexity of reaction conditions, which has impeded their widespread application. Therefore, this study was conducted to evaluate deficiencies in trace elements during anaerobic digestion by establishing relationships between changes in trace element bioavailability (the degree to which elements are available for interaction with biological systems) and digestion performance. To accomplish this, two batch experiments were conducted. In the first, sequential extraction was used to detect changes in trace element fractions and then to evaluate trace element bioavailability in the whole digestion cycle. In the second batch experiment, trace elements (Co, Fe, Cu, Zn, Mn, Mo and Se) were added to the reaction system at three concentrations (low, medium and high) and their effects were monitored. The results showed that sequential extraction was a suitable method for assessment of the bioavailability of trace elements (appropriate coefficient of variation and recovery rate). The results revealed that Se had the highest (44.2%-70.9%) bioavailability, while Fe had the lowest (1.7%-3.0%). A lack of trace elements was not directly related to their absolute bioavailability, but was instead associated with changes in their bioavailability throughout the digestion cycle. Trace elements were insufficient when their bioavailability was steady or increased over the digestion cycle. These results indicate that changes in trace element bioavailability during the digestion cycle can be used to predict their deficiency. Copyright © 2018 Elsevier Ltd. All rights reserved.
Blose, Julia E; Mack, Rhonda W
2009-01-01
Using a scenario-based approach, an experiment is conducted to test whether the decision a physician makes to deny a prescription request (when a patient has requested a drug he or she has seen in a direct-to-consumer [DTC] ad) significantly impacts patient outcomes such as patient satisfaction and compliance intentions. The results suggest physicians can expect patient response to the denial of such a request to vary by the patient's gender in addition to the criticality of the condition being treated. The results also suggest, when treating less critical conditions, a physician can mitigate the negative effects of a denial with relatively little additional effort.
The effects of trace element content on pyrite oxidation rates
NASA Astrophysics Data System (ADS)
Gregory, D. D.; Lyons, T.; Cliff, J. B.; Perea, D. E.; Johnson, A.; Romaniello, S. J.; Large, R. R.
2017-12-01
Pyrite acts as both an important source and sink for many different metals and metalloids in the environment, including many that are toxic. Oxidation of pyrite can release these elements while at the same time producing significant amounts of sulfuric acid. Such issues are common in the vicinity of abandoned mines and smelters, but, as pyrite is a common accessory mineral in many different lithologies, significant pyrite oxidation can occur whenever pyritic rocks are exposed to oxygenated water or the atmosphere. Accelerated exposure to oxygen can occur during deforestation, fracking for petroleum, and construction projects. Geochemical models for pyrite oxidation can help us develop strategies to mitigate these deleterious effects. An important component of these models is an accurate pyrite oxidation rate; however, current pyrite oxidation rates have been determined using relatively pure pyrite. Natural pyrite is rarely pure and has a wide range of trace element concentrations that may affect the oxidation rate. Furthermore, the position of trace elements within the mineral lattice can also affect the oxidation rate. For example, elements such as Ni and Co, which substitute into the pyrite lattice, are thought to stabilize the lattice and thus prevent pyrite oxidation. Alternatively, trace elements that are held within inclusions of other minerals could form a galvanic cell with the surrounding pyrite, thus enhancing pyrite oxidation rates. In this study, we present preliminary analyses from three different pyrite oxidation experiments each using natural pyrite with different trace element compositions. These results show that the pyrite with the highest trace element concentration has approximately an order of magnitude higher oxidation rate compared to the lowest trace element sample. To further elucidate the mechanisms, we employed microanalytical techniques to investigate how the trace elements are held within the pyrite. LA-ICPMS was used to determine the variability of trace element content from the pyrite samples. These data were then used to select areas of interest for NanoSIMS analyses, which in turn was used to select areas for TEM and APT. These analyses show that the trace element content of pyrite can be highly variable, which may significantly affect the rate of pyrite oxidation.
76 FR 57749 - Information Collection Request to Office of Management and Budget
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2011-09-16
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17 CFR 200.305 - Special procedure: Medical records.
Code of Federal Regulations, 2012 CFR
2012-04-01
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Code of Federal Regulations, 2014 CFR
2014-04-01
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Code of Federal Regulations, 2011 CFR
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Code of Federal Regulations, 2010 CFR
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Code of Federal Regulations, 2013 CFR
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Tracing the Attention of Moving Citizens
Wu, Lingfei; Wang, Cheng-Jun
2016-01-01
With the widespread use of mobile computing devices in contemporary society, our trajectories in the physical space and virtual world are increasingly closely connected. Using the anonymous smartphone data of 1 × 105 users in a major city of China, we study the interplay between online and offline human behaviors by constructing the mobility network (offline) and the attention network (online). Using the network renormalization technique, we find that they belong to two different classes: the mobility network is small-world, whereas the attention network is fractal. We then divide the city into different areas based on the features of the mobility network discovered under renormalization. Interestingly, this spatial division manifests the location-based online behaviors, for example shopping, dating, and taxi-requesting. Finally, we offer a geometric network model to help us understand the relationship between small-world and fractal networks. PMID:27608929
Anonymity and Historical-Anonymity in Location-Based Services
NASA Astrophysics Data System (ADS)
Bettini, Claudio; Mascetti, Sergio; Wang, X. Sean; Freni, Dario; Jajodia, Sushil
The problem of protecting user’s privacy in Location-Based Services (LBS) has been extensively studied recently and several defense techniques have been proposed. In this contribution, we first present a categorization of privacy attacks and related defenses. Then, we consider the class of defense techniques that aim at providing privacy through anonymity and in particular algorithms achieving “historical k- anonymity” in the case of the adversary obtaining a trace of requests recognized as being issued by the same (anonymous) user. Finally, we investigate the issues involved in the experimental evaluation of anonymity based defense techniques; we show that user movement simulations based on mostly random movements can lead to overestimate the privacy protection in some cases and to overprotective techniques in other cases. The above results are obtained by comparison to a more realistic simulation with an agent-based simulator, considering a specific deployment scenario.
2012-12-01
Effectiveness Report to Congressional Requesters December 2012 GAO-13-29 United States Government Accountability Office GAO Report Documentation...TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Government Accountability Office,441 G Street NW,Washington...by ANSI Std Z39-18 United States Government Accountability Office Highlights of GAO-13-29, a report to congressional requesters
Introductory Laboratory Exercises in Radiobiology
ERIC Educational Resources Information Center
Williams, J. R. Parry; Servant, D. M.
1970-01-01
Describes experiments suitable for introducing use of radioisotopes in biology. Includes demonstrations of tracing food chains, uptake of ions by plants, concentration of elements by insects, tracing photosynthetic reactions, activation analysis of copper, and somatic and genetic effects. Uses autoradiographic and counting techniques. (AL)
Kaneko, T; Thompson, R F
1997-05-01
Central muscarinic cholinergic involvement in classical conditioning of eyeblink responses was determined in trace and delay paradigms. Rabbits were trained on a trace procedure in which a 250-ms tone conditioned stimulus (CS) and a 100-ms air-puff unconditioned stimulus (UCS) were presented with a 500-ms trace interval. Each training session day consisted of ten tone alone, ten air-puff alone and 80 paired CS-UCS trials. Scopolamine hydrochloride at doses of 0.03 and 0.1 mg/0.5 ml per kg, s.c. dose-dependently disrupted acquisition of conditioned responses. Rabbits that were treated with scopolamine and failed to learn showed a gradual increase in conditioned responses during an additional training period with saline injections and no transfer from earlier training. Scopolamine methyl bromide, which does not appreciably cross the blood-brain barrier, showed no effects in the trace conditioning paradigm at a dose of 0.1 mg/kg, s.c., indicating central cholinergic blockade is responsible for the suppressive effect of scopolamine. Scopolamine hydrochloride at a dose of 0.1 mg/kg, s.c. did not block acquisition in the delay procedure with a 250-ms inter-stimulus interval, although the rate of acquisition was somewhat reduced by the drug. These data are the first to demonstrate that classical conditioning of the eyeblink response in the trace procedure is highly sensitive to central cholinergic deficits.
Kouvo, Petri
2003-04-01
This work focused on trace metal behavior and removal in a fabric filter or in a humidification reactor during the cofiring of sawdust and refuse-derived fuels (RDFs) in a pilot-scale bubbling fluidized bed (BFB) boiler. Trace metal emissions measurements before and after the fabric filter revealed that removal efficiency in the fabric filter was in the range of 80-100%, and that the European Union (EU) Directive on Incineration of Waste restrictions for trace metal emissions are easily achieved even if addition of RDFs substantially increases the concentration of trace metals in fuel blends. Limestone injection enhanced the removal of As and Se but had no noticeable effect on the removal of other trace metals. Extensive formation of HgCl2 and condensation on fly ash particles during sawdust plus 40% RDF cofiring resulted in a 92% Hg removal efficiency in the fabric filter. Limestone injection had no effect on the Hg removal in the fabric filter but decreased the Hg removal in a humidification reactor from 40 to 28%. Results of the bed material and fly ash analysis suggested capture of Cu, Pb, Mn, Ni, and Zn in the bed material but also suggested that these metals may be released from the bed if the fuel characteristics or process conditions are changed.
NASA Astrophysics Data System (ADS)
Wang, Rongxi; Gao, Xu; Gao, Jianmin; Gao, Zhiyong; Kang, Jiani
2018-02-01
As one of the most important approaches for analyzing the mechanism of fault pervasion, fault root cause tracing is a powerful and useful tool for detecting the fundamental causes of faults so as to prevent any further propagation and amplification. Focused on the problems arising from the lack of systematic and comprehensive integration, an information transfer-based novel data-driven framework for fault root cause tracing of complex electromechanical systems in the processing industry was proposed, taking into consideration the experience and qualitative analysis of conventional fault root cause tracing methods. Firstly, an improved symbolic transfer entropy method was presented to construct a directed-weighted information model for a specific complex electromechanical system based on the information flow. Secondly, considering the feedback mechanisms in the complex electromechanical systems, a method for determining the threshold values of weights was developed to explore the disciplines of fault propagation. Lastly, an iterative method was introduced to identify the fault development process. The fault root cause was traced by analyzing the changes in information transfer between the nodes along with the fault propagation pathway. An actual fault root cause tracing application of a complex electromechanical system is used to verify the effectiveness of the proposed framework. A unique fault root cause is obtained regardless of the choice of the initial variable. Thus, the proposed framework can be flexibly and effectively used in fault root cause tracing for complex electromechanical systems in the processing industry, and formulate the foundation of system vulnerability analysis and condition prediction, as well as other engineering applications.
Mapping Fifteen Trace Elements in Human Seminal Plasma and Sperm DNA.
Ali, Sazan; Chaspoul, Florence; Anderson, Loundou; Bergé-Lefranc, David; Achard, Vincent; Perrin, Jeanne; Gallice, Philippe; Guichaoua, Marie
2017-02-01
Studies suggest a relationship between semen quality and the concentration of trace elements in serum or seminal plasma. However, trace elements may be linked to DNA and capable of altering the gene expression patterns. Thus, trace element interactions with DNA may contribute to the mechanisms for a trans-generational reproductive effect. We developed an analytical method to determine the amount of trace elements bound to the sperm DNA, and to estimate their affinity for the sperm DNA by the ratio: R = Log [metal concentration in the sperm DNA/metal concentration in seminal plasma]. We then analyzed the concentrations of 15 trace elements (Al, Cd, Cr, Cu, Hg, Mn, Mo, Ni, Pb, Ti, V, Zn, As, Sb, and Se) in the seminal plasma and the sperm DNA in 64 normal and 30 abnormal semen specimens with Inductively Coupled Plasma/Mass Spectrometry (ICP-MS). This study showed all trace elements were detected in the seminal plasma and only metals were detected in the sperm DNA. There was no correlation between the metals' concentrations in the seminal plasma and the sperm DNA. Al had the highest affinity for DNA followed by Pb and Cd. This strong affinity is consistent with the known mutagenic effects of these metals. The lowest affinity was observed for Zn and Ti. We observed a significant increase of Al linked to the sperm DNA of patients with oligozoospermia and teratozoospermia. Al's reproductive toxicity might be due to Al linked to DNA, by altering spermatogenesis and expression patterns of genes involved in the function of reproduction.
Woods, Brenda; Lennard, Chris; Kirkbride, K Paul; Robertson, James
2016-05-01
In the past, forensic soil examination was a routine aspect of forensic trace evidence examinations. The apparent need for soil examinations then went through a period of decline and with it the capability of many forensic laboratories to carry out soil examinations. In more recent years, interest in soil examinations has been renewed due-at least in part-to soil examinations contributing to some high profile investigations. However, much of this renewed interest has been in organisations with a primary interest in soil and geology rather than forensic science. We argue the need to reinstate soil examinations as a trace evidence sub-discipline within forensic science laboratories and present a pathway to support this aim. An examination procedure is proposed that includes: (i) appropriate sample collection and storage by qualified crime scene examiners; (ii) exclusionary soil examinations by trace evidence scientists within a forensic science laboratory; (iii) inclusionary soil examinations by trace evidence scientists within a forensic science laboratory; and (iv) higher-level examination of soils by specialist soil scientists and palynologists. Soil examinations conducted by trace evidence scientists will be facilitated if the examinations are conducted using the instrumentation routinely used by these examiners. Hence, the proposed examination protocol incorporates instrumentation in routine use in a forensic trace evidence laboratory. Finally, we report on an Australian soil scene variability study and a blind trial that demonstrate the utility of the proposed protocol for the effective triage and management of soil samples by forensic laboratories. Crown Copyright © 2016. Published by Elsevier Ireland Ltd. All rights reserved.
M'Sadeq, Shawkat A; Wu, Shu-Biao; Choct, Mingan; Swick, Robert A
2018-05-26
This experiment was conducted to examine the effect of trace mineral sources on broiler performance, carcass composition, trace mineral digestibility, and tibia bone quality of broiler chickens. A total of 480 Ross 308 male day-old chicks were allocated to 24 pens and assigned to 4 dietary treatments in a completely randomized design. Treatments were as follows: inorganic (I) was basal diet supplemented with 750 g/t inorganic trace mineral premix; organic 1 (O1) and organic 2 (O2) was basal diet supplemented with 375 and 500 g/t organic yeast proteinate trace mineral premix respectively; and hydroxychloride (H) was basal diet supplemented with 1000 g/t salt encrusted trace mineral premix. On day 25, no differences in feed intake (FI), body weight gain (BWG), feed conversion ratio (FCR), or livability (LV) were observed between treatments (P > 0.05). On day 38 birds fed O1 and H had higher weight gain (P < 0.05) and lower FCR (P < 0.001) relative to I. Mineral sources had no impact on FI or LV (P > 0.05) on day 38. Spleen percentage of body weight on day 25 was increased in birds fed O1 and H treatments (P < 0.05) over the I treatment. Mineral sources had no effect on relative weights of thymus or bursa of Fabricius on day 25, or bone quality and carcass composition on day 39 (P > 0.05). Apparent digestibilities of Cu and Zn were greater in birds fed yeast proteinated trace minerals compared to other sources.
SAIL: automating interlibrary loan.
Lacroix, E M
1994-01-01
The National Library of Medicine (NLM) initiated the System for Automated Interlibrary Loan (SAIL) pilot project to study the feasibility of using imaging technology linked to the DOCLINE system to deliver copies of journal articles. During the project, NLM converted a small number of print journal issues to electronic form, linking the captured articles to the MEDLINE citation unique identifier. DOCLINE requests for these journals that could not be filled by network libraries were routed to SAIL. Nearly 23,000 articles from sixty-four journals recently selected for indexing in Index Medicus were scanned to convert them to electronic images. During fiscal year 1992, 4,586 scanned articles were used to fill 10,444 interlibrary loan (ILL) requests, and more than half of these were used only once. Eighty percent of all the articles were not requested at all. The total cost per article delivered was $10.76, substantially more than it costs to process a photocopy request. Because conversion costs were the major component of the total SAIL cost, and most of the articles captured for the project were not requested, this model was not cost-effective. Data on SAIL journal article use was compared with all ILL requests filled by NLM for the same period. Eighty-eight percent of all articles requested from NLM were requested only once. The results of the SAIL project demonstrated that converting journal articles to electronic images and storing them in anticipation of repeated requests would not meet NLM's objective to improve interlibrary loan. PMID:8004020
SAIL: automating interlibrary loan.
Lacroix, E M
1994-04-01
The National Library of Medicine (NLM) initiated the System for Automated Interlibrary Loan (SAIL) pilot project to study the feasibility of using imaging technology linked to the DOCLINE system to deliver copies of journal articles. During the project, NLM converted a small number of print journal issues to electronic form, linking the captured articles to the MEDLINE citation unique identifier. DOCLINE requests for these journals that could not be filled by network libraries were routed to SAIL. Nearly 23,000 articles from sixty-four journals recently selected for indexing in Index Medicus were scanned to convert them to electronic images. During fiscal year 1992, 4,586 scanned articles were used to fill 10,444 interlibrary loan (ILL) requests, and more than half of these were used only once. Eighty percent of all the articles were not requested at all. The total cost per article delivered was $10.76, substantially more than it costs to process a photocopy request. Because conversion costs were the major component of the total SAIL cost, and most of the articles captured for the project were not requested, this model was not cost-effective. Data on SAIL journal article use was compared with all ILL requests filled by NLM for the same period. Eighty-eight percent of all articles requested from NLM were requested only once. The results of the SAIL project demonstrated that converting journal articles to electronic images and storing them in anticipation of repeated requests would not meet NLM's objective to improve interlibrary loan.
Zhu, Zongmin; Xue, Junhui; Deng, Yuzhen; Chen, Lin; Liu, Jiangfeng
2016-04-15
Based on geochemical and magnetic approaches, the distribution, sources, and health risk of trace metals in surface sediments from a seashore tourist city were investigated. A significant correlation was found between magnetic susceptibility (χ) and trace metals, which suggested that levels of trace metals in the sediments can be effectively depicted by the magnetic approach. The spatial distribution of χ and trace metals matched well with the city layout with relatively higher values being found in the port and busy tourist areas. This result, together with enrichment factors (EFs) and Tomlinson pollution load index (PLI) of metals, suggested that the influence of human activities on the coastal environment was noticeable. Principal component analysis (PCA) indicated that trace metals in the sediments were derived from both anthropogenic and natural sources. Noncarcinogenic risk assessment showed that there was no potential health risk of exposure to metals by means of ingestion or inhalation. Copyright © 2016 Elsevier Ltd. All rights reserved.
Memory and consciousness: trace distinctiveness in memory retrievals.
Brunel, Lionel; Oker, Ali; Riou, Benoit; Versace, Rémy
2010-12-01
The aim of this article was to provide experimental evidence that classical dissociation between levels of consciousness associated with memory retrieval (i.e., implicit or explicit) can be explained in terms of task dependency and distinctiveness of traces. In our study phase, we manipulated the level of isolation (partial vs. global) of the memory trace by means of an isolation paradigm (isolated words among non-isolated words). We then tested these two types of isolation in a series of tasks of increasing complexity: a lexical decision task, a recognition task, and a free recall task. The main result of this study was that distinctiveness effects were observed as a function of the type of isolation (level of isolation) and the nature of the task. We concluded that trace distinctiveness improves subsequent access to the trace, while the level of trace distinctiveness also appears to determine the possibility of conscious or explicit retrieval. Copyright © 2010 Elsevier Inc. All rights reserved.
Serrano, A; Pinto-Ibieta, F; Braga, A F M; Jeison, D; Borja, R; Fermoso, F G
2017-12-01
Low concentrations of trace elements in many organic wastes recommend their supplementation in order to avoid potential limitations. Different chelating agents have been used to ensure an adequate trace metal pool in the soluble fraction, by forming dissolved complexes. Ethylenediaminetetraacetic acid (EDTA) is probably the most common, although several negative effects could be associated with its usage. Biomethane potential tests were performed using Olive Mill Solid Waste as the substrate, supplementing different combinations of Fe, Co, Ni, Ba, always under the presence of EDTA. Results show that Ni and Co slightly recovered biodegradability. However, Ba supplementation resulted in worsening the methane yield coefficient in all cases. High concentration of EDTA led to decrease in the activity of anaerobic digestion. High availability of EDTA induces the capture of trace metals like Co or Ni, key trace metals for anaerobic biomass activity. While supplementing trace metals, the addition of Ba and/or EDTA must be carefully considered.
ERIC Educational Resources Information Center
Hinderliter, Charles F.; Andrews, Amy; Misanin, James R.
2012-01-01
In conditioned taste aversion (CTA), a taste, the conditioned stimulus (CS), is paired with an illness-inducing stimulus, the unconditioned stimulus (US), to produce CS-US associations at very long (hours) intervals, a result that appears to violate the law of contiguity. The specific length of the maximum effective trace interval that has been…
Alghadir, Ahmad H; Gabr, Sami A; Al-Eisa, Einas S
2015-01-01
Homeostatic imbalance of trace elements such as iron (Fe), copper (Cu), and zinc (Zn) demonstrated adverse effects on brain function among older adults. The present study aimed to investigate the effects of trace elements and the presence of anti-glutamic acid decarboxylase antibodies (GADAs) in human cognitive abilities among healthy older adults. A total of 100 healthy subjects (65 males, 35 females; age range; 64-96 years) were recruited for this study. Based on Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) score, the participants were classified according to cognitive performance into normal (n=45), moderate (n=30), and severe (n=25). Cognitive functioning, leisure-time physical activity (LTPA), serum trace elements - Fe, Cu, Zn, Zn/Cu, and GADAs were assessed using LOTCA battery, pre-validated physical activity (PA) questionnaire, atomic absorption, and immunoassay techniques, respectively. Approximately 45% of the study population (n=45) had normal distribution of cognitive function and 55% of the study population (n=55) had abnormal cognitive function; they were classified into moderate (score 62-92) and severe (score 31-62). There was a significant reduction in the level of Zn and Zn/Cu ratio along with an increase in the level of Fe, Cu, and anti-GADAs in subjects of severe (P=0.01) and moderate (P=0.01) cognitive performance. LOTCA-cognitive scores correlated positively with sex, HbA(1c), Fe, Cu, Zn, and Zn/Cu ratio, and negatively with age, PA, body mass index, and anti-GADAs. Significant inter-correlation was reported between serum trace element concentrations and anti-GADAs which suggest producing a cognitive decline via oxidative and neural damage mechanism. This study found significant associations among trace elements, anti-GADAs, and cognitive function in older adults. The homeostatic balance of trace elements should be recommended among older adults for better cognitive performance.
A review of recent activity in the United States.
Cannon, H.L.; Petrie, W.L.
1979-01-01
Either an overabundance or a deficiency of trace metals in the food chain can ultimately affect adversely the health of livestock and man. Increasing interest in the United States in the distribution of metals in the environment and in metal pollutants has led to widespread interdisciplinary research sponsored by governmental, private and academic groups concerning the availability of trace elements for absorption by plants and animals, and the effects of trace elements throughout the food chain. Effects on the environment of coal-fired power plants, the mining and processing of metals, asbestos, and phosphate, and the disposal of industrial and nuclear wastes have also received much attention in the past few years.-Authors
Morgan, Matthew B; Young, Elizabeth; Harada, Scott; Winkler, Nicole; Riegert, Joanna; Jones, Tony; Hu, Nan; Stein, Matthew
2017-12-01
In screening mammography, accessing prior examination images is crucial for accurate diagnosis and avoiding false-positives. When women visit multiple institutions for their screens, these "outside" examinations must be retrieved for comparison. Traditionally, prior images are obtained by faxing requests to other institutions and waiting for standard mail (film or CD-ROM), which can greatly delay report turnaround times. Recently, advancements in cloud-based image transfer technology have opened up more efficient options for examination transfer between institutions. The objective of this study was to evaluate the effect of cloud-based image transfer on mammography department workflow, time required to obtain prior images, and report turnaround times. Sixty screening examinations requiring prior images were placed into two groups (30 each). The control group used the standard institutional protocol for requesting prior images: faxing requests and waiting for mailed examinations. The experimental group used a cloud-based transfer for both requesting and receiving examinations. The mean number of days between examination request and examination receipt was measured for both groups and compared. The mean number of days from examination request to receipt was 6.08 days (SD 3.50) in the control group compared with 3.16 days (SD 3.95) in the experimental group. Using a cloud-based image transfer to obtain prior mammograms resulted in an average reduction of 2.92 days (P = .0361; 95% confidence interval 0.20-5.65) between examination request and receipt. This improvement in system efficiency is relevant for interpreting radiologists working to improve reporting times and for patients anxious to receive their mammography results. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.
Schmidt, Thomas; Nelles, Michael; Scholwin, Frank; Pröter, Jürgen
2014-09-01
A trace element dosing strategy for the anaerobic digestion of wheat stillage was developed in this study. Mesophilic CSTR reactors were operated with the sulfuric substrate wheat stillage in some cases under trace element deficiency. After supplementing trace elements during the start-up, one of the elements of Fe, Ni, Co, Mo, and W were depleted in one digester while still augmenting the other elements to determine minimum requirements for each element. The depletion of Fe and Ni resulted in a rapid accumulation of volatile fatty acids while Co and W seem to have a long-term effect. Based on the results it was possible to reduce the dosing of trace elements, which is positive with reference to economic and environmental aspects. Copyright © 2014 Elsevier Ltd. All rights reserved.
NASA Technical Reports Server (NTRS)
Liu, Nan-Suey; Wey, Thomas
2001-01-01
Many of the engine exhaust species resulting in significant environmental impact exist in trace amounts. Recent research, e.g., conducted at MIT-AM, has pointed to the intra-engine environment as a possible site for important trace chemistry activity. In addition, the key processes affecting the trace species activity occurring downstream in the air passages of the turbine and exhaust nozzle are not well understood. Most recently, an effort has been initiated at NASA Glenn Research Center under the UEET Program to evaluate and further develop CFD-based technology for modeling and simulation of intra-engine trace chemical changes relevant to atmospheric effects of pollutant emissions from aircraft engines. This presentation will describe the current effort conducted at Glenn; some preliminary results relevant to the trace species chemistry in a turbine passage will also be presented to indicate the progress to date.
Nielsen, Forrest H
2014-10-01
Today, most nutritionists do not consider a trace element essential unless it has a defined biochemical function in higher animals or humans. As a result, even though it has been found that trace elements such as boron and silicon have beneficial bioactivity in higher animals and humans, they generally receive limited attention or mention when dietary guidelines or intake recommendations are formulated. Recently, the possibility of providing dietary intake recommendations such as an adequate intake (AI) for some bioactive food components (e.g., flavonoids) has been discussed. Boron, chromium, nickel, and silicon are bioactive food components that provide beneficial health effects by plausible mechanisms of action in nutritional and supra nutritional amounts, and thus should be included in the discussions. Although the science base may not be considered adequate for establishing AIs, a significant number of findings suggest that statements about these trace elements should be included when dietary intake guidance is formulated. An appropriate recommendation may be that diets should include foods that would provide trace elements not currently recognized as essential in amounts shown to reduce the risk of chronic disease and/or promote health and well-being. Published by Elsevier GmbH.
The interpersonal process in tissue donation requests with “undecided” next of kin
Dorflinger, Lindsey; Auerbach, Stephen M.; Siminoff, Laura A.
2012-01-01
Context Although recent studies have demonstrated that tissue requesters’ behavior during conversations about tissue donation affects consent rates, the link between requesters’ behavior and consent rates remains unclear. Objective To examine whether positive/collaborative requester behaviors elicit complementary behaviors from next of kin who were initially undecided about their willingness to donate their deceased family member’s tissues. Design Audio recordings of requests were coded to assess for interpersonal behavior of each interactant. Setting Audio recordings were gathered from a national sample of tissue banks. Participants One hundred and two requester–next-of-kin dyads, consisting of 102 relatives and 53 requesters. Main Outcome Measures Tissue requester and next-of-kin affiliation and interpersonal control were assessed. Tissue requesters’ persuasion, confirmation (eg, approval, empathy, reassurance) and disapproval, as well as next-of-kin approval and disapproval, were examined. Results Tissue requesters and next of kin tended to match one another on affiliation and complement one another on interpersonal control. “Key topics,” which may affect the next of kin’s decision, are discussed in only about one-third of requests. Next of kin were less affiliative and more disapproving when requesters were also more disapproving. Interpersonal behavior of the tissue requester, such as affiliation, statements of disapproval, and persuasion, as well as discussion of key topics, was a significant predictor of the interpersonal behavior of the next of kin. Conclusions Positive requester behaviors elicited a positive response from undecided next of kin. Because many next of kin have limited knowledge about tissue donation before the request, the communication process may affect the next of kin’s perceptions of donation and thus affect the likelihood of consent. Findings could potentially inform communication skills training for tissue requesters; future research could examine effects of such training on consent rates. PMID:23187062
Shulman, Stanley A.; Brisson, Michael J.; Howe, Alan M.
2015-01-01
Inductively coupled plasma mass spectrometry (ICP-MS) is becoming more widely used for trace elemental analysis in the occupational hygiene field, and consequently new ICP-MS international standard procedures have been promulgated by ASTM International and ISO. However, there is a dearth of interlaboratory performance data for this analytical methodology. In an effort to fill this data void, an interlaboratory evaluation of ICP-MS for determining trace elements in workplace air samples was conducted, towards fulfillment of method validation requirements for international voluntary consensus standard test methods. The study was performed in accordance with applicable statistical procedures for investigating interlaboratory precision. The evaluation was carried out using certified 37-mm diameter mixed-cellulose ester (MCE) filters that were fortified with 21 elements of concern in occupational hygiene. Elements were spiked at levels ranging from 0.025 to 10 μg filter−1, with three different filter loadings denoted “Low”, “Medium” and “High”. Participating laboratories were recruited from a pool of over fifty invitees; ultimately twenty laboratories from Europe, North America and Asia submitted results. Triplicates of each certified filter with elemental contents at three different levels, plus media blanks spiked with reagent, were conveyed to each volunteer laboratory. Each participant was also provided a copy of the test method which each participant was asked to follow; spiking levels were unknown to the participants. The laboratories were requested to prepare the filters by one of three sample preparation procedures, i.e., hotplate digestion, microwave digestion or hot block extraction, which were described in the test method. Participants were then asked to analyze aliquots of the prepared samples by ICP-MS, and to report their data in units of μg filter−1. Most interlaboratory precision estimates were acceptable for medium- and high-level spikes (RSD <25%), but generally yielded greater uncertainties than were anticipated at the outset of the study. PMID:22038017
76 FR 5374 - Agency Information Collection Activities: Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-31
... Request. Form Title: Notice of Claim and Proof of Loss, Working Capital Guarantee. SUMMARY: The Export..., guarantees, insurance and working capital credits. By neutralizing the effect of export credit support.... Under the Working Capital Guarantee Program, Ex-Im Bank provides repayment guarantees to lenders on...
42 CFR 90.3 - Procedures for requesting health assessments.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 1 2010-10-01 2010-10-01 false Procedures for requesting health assessments. 90.3 Section 90.3 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES ADMINISTRATIVE...
77 FR 4041 - Agency Information Collection Activities: Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-26
... Healthcare Research and Quality (AHRQ) to request that the Office of Management and Budget (OMB) approve the proposed information collection project: ``Assessing the Feasibility of Disseminating Effective Health Care Products through a Shared Electronic Medical Record Serving Member Organization of a Health Information...
78 FR 78985 - Agency Information Collection Activities: Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-27
...) will publish periodic summaries of proposed projects. To request more information on the proposed... the effects and accomplishments of SAMHSA programs. The following table is an estimated annual... transaction \\1\\ This table represents the maximum additional burden if adult respondents for ATR provide...
78 FR 24159 - Proposed Information Collection; Comment Request; International Import Certificate
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-24
... several other countries have increased the effectiveness of their respective controls over international... information collection). Affected Public: Business or other for-profit organizations. Estimated Number of... Total Annual Cost to Public: $0. IV. Request for Comments Comments are invited on: (a) Whether the...
ARCC Teacher Compensation Initiative: Literature Review
ERIC Educational Resources Information Center
Appalachia Regional Comprehensive Center, 2014
2014-01-01
In February 2014, the Tennessee State Board of Education (SBE) requested that the Appalachia Regional Comprehensive Center (ARCC) provide assistance to the SBE's Basic Education Program (BEP) Review Committee. The SBE requested additional information on the use and effectiveness of market-based teacher compensation and market-based incentives by…
76 FR 65315 - Agency Information Collection Activities: Proposed Request and Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-20
... a benefit offset alone and in conjunction with enhanced work incentives counseling. The central...? What is the effect of the benefit offset in combination with enhanced work incentives counseling on... of enhanced work incentives counseling on SSDI beneficiaries' work efforts and earnings. Ultimately...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-15
.... SUMMARY: The Department of Labor (DOL) is submitting the Occupational Safety and Health Administration (OSHA) sponsored information collection request (ICR) titled, ``Standard on 4,4'-Methylenedianiline in...'-Methylenedianiline (MDA) in Construction protects workers from adverse health effects associated with occupational...
78 FR 54660 - Agency Information Collection Activities; Proposed Collection; Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-05
... reference. Information Collection Request Title: HRSA Telehealth Outcome Measures. OMB No.: 0915-0311...) created a set of performance measures that grantees can use to evaluate the effectiveness of their...), all federal agencies must develop strategic plans describing their overall goal and objectives. The...
75 FR 5330 - Agency Information Collection Request. 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-02
... officials and healthcare systems to ensure effective integration of Federal public health and medical assets... DEPARTMENT OF HEALTH AND HUMAN SERVICES [Document Identifier: OS-0990-0344 Extension] Agency... of the Secretary (OS), Department of Health and Human Services, is publishing the following summary...
76 FR 3877 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-21
...: Communication and Outreach. OMB Control Number: None. Form Number(s): None. Type of Request: Emergency... be used to revise/ update its collateral materials, outreach strategies and program services in a manner that effectively matches the interests and needs of its core constituency and outreach strategies...
77 FR 5227 - Information Collection Request; Debt Settlement Policies and Procedures
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-02
... Commodity Credit Corporation (CCC) are requesting comments from all interested individuals and organizations on an extension of a currently approved information collection that supports the FSA and CCC Debt... revision. Abstract: This information collection is needed to enable FSA and CCC to effectively administer...
Distinct molecular underpinnings of Drosophila olfactory trace conditioning
Shuai, Yichun; Hu, Ying; Qin, Hongtao; Campbell, Robert A. A.; Zhong, Yi
2011-01-01
Trace conditioning is valued as a simple experimental model to assess how the brain associates events that are discrete in time. Here, we adapted an olfactory trace conditioning procedure in Drosophila melanogaster by training fruit flies to avoid an odor that is followed by foot shock many seconds later. The molecular underpinnings of the learning are distinct from the well-characterized simultaneous conditioning, where odor and punishment temporally overlap. First, Rutabaga adenylyl cyclase (Rut-AC), a putative molecular coincidence detector vital for simultaneous conditioning, is dispensable in trace conditioning. Second, dominant-negative Rac expression, thought to sustain early labile memory, significantly enhances learning of trace conditioning, but leaves simultaneous conditioning unaffected. We further show that targeting Rac inhibition to the mushroom body (MB) but not the antennal lobe (AL) suffices to achieve the enhancement effect. Moreover, the absence of trace conditioning learning in D1 dopamine receptor mutants is rescued by restoration of expression specifically in the adult MB. These results suggest the MB as a crucial neuroanatomical locus for trace conditioning, which may harbor a Rac activity-sensitive olfactory “sensory buffer” that later converges with the punishment signal carried by dopamine signaling. The distinct molecular signature of trace conditioning revealed here shall contribute to the understanding of how the brain overcomes a temporal gap in potentially related events. PMID:22123966
Maternal request CS--role of hospital teaching status and for-profit ownership.
Xirasagar, Sudha; Lin, Herng-Ching
2007-05-01
To examine whether hospitals' for-profit (FP) ownership and non-teaching status are associated with greater likelihood of maternal request cesarean (CS) relative to public and not-for-profit (NFP) and teaching status, respectively. Retrospective, cross-sectional, population-based study of Taiwan's National Health Insurance claims data, covering all 739,531 vaginal delivery-eligible singleton deliveries during 1997-2000, using multiple logistic regression analyses. Adjusted for maternal age and geographic location, FP district hospitals (almost all non-teaching), followed by ob/gyn clinics were significantly more likely to perform request CS (OR=3.5-2.3) than public and NFP teaching hospitals. Among non-teaching and teaching hospitals, FPs were more likely to perform request CS than public and NFP hospitals (OR=2.3 and 2.5, respectively). Our findings are consistent with greater propensity of physicians in FP institutions to accommodate patient requests involving revenue-maximizing procedures such as request CS. This effect is moderated by teaching hospitals' preference for complicated cases, consistent with their teaching mission and hi-tech infrastructure.
The vascular effects of trace amines and amphetamines.
Broadley, Kenneth J
2010-03-01
Trace amines, including tyramine, beta-phenylethylamine (beta-PEA), tryptamine and octopamine, are biologically active amines mostly based on phenylethylamine, occurring in the body in trace amounts. They are a diverse group of naturally occurring and synthetic amines, which are also found in the diet and in herbal plants, such as ephedrine and cathinone. They include amphetamine and its analogues, such as MDMA ('ecstasy'), and synthetic proprietary sympathomimetic agents such as phenylpropanolamine and pseudoephedrine. On the vascular system they cause vasoconstriction and a rise in blood pressure. This effect is the basis of their use as nasal decongestants. For over 50 years, they have been assumed to be indirectly acting sympathomimetic amines, their responses being due to the release of noradrenaline from sympathetic neurones. There are, however, results that suggest that this is not their only mechanism of action and that they may also exert direct vascular effects independent of a noradrenergic mechanism. Recently, a group of novel trace amine-associated receptors (TAARs) have been cloned and identified in the brain and peripheral tissues including blood vessels. Trace amines bind to these cloned receptors and it is suggested that their vasoconstrictor effects can in part be attributed to this mechanism. This review describes the cardiovascular pharmacology of this diverse group of amines, their structures and uses and their endogenous synthesis and metabolism. The review also considers their clinical relevance as constituents of the diet, as therapeutic agents (ritodrine, phenylpropanolamine, and pseudoephedrine) and as drugs of abuse (amphetamine, 'ecstasy') and their mechanisms of action. 2009 Elsevier Inc. All rights reserved.
Functional role of inorganic trace elements in angiogenesis-Part II: Cr, Si, Zn, Cu, and S.
Saghiri, Mohammad Ali; Asatourian, Armen; Orangi, Jafar; Sorenson, Christine M; Sheibani, Nader
2015-10-01
Trace elements play critical roles in angiogenesis events. The effects of nitrogen, iron, selenium, phosphorus, gold, and calcium were discussed in part I. In part II, we evaluated the effect of chromium, silicon, zinc, copper, and sulfur on different aspects of angiogenesis, with critical roles in healing and regeneration processes, and undeniable roles in tumor growth and cancer therapy. This review is the second of series that serves as an overview of the role of inorganic elements in regulation of angiogenesis and vascular function. The methods of exposure, structure, mechanism, and potential activity of these trace elements are briefly discussed. An electronic search was performed on the role of these trace elements in angiogenesis from January 2005 to April 2014. The recent aspects of the relationship between five different trace elements and their role in regulation of angiogenesis, and homeostasis of pro- and anti-angiogenic factors were assessed. Many studies have investigated the effects and importance of these elements in angiogenesis events. Both stimulatory and inhibitory effects on angiogenesis are observed for the evaluated elements. Chromium can promote angiogenesis in pathological manners. Silicon as silica nanoparticles is anti-angiogenic, while in calcium silicate extracts and bioactive silicate glasses promote angiogenesis. Zinc is an anti-angiogenic agent acting on important genes and growth factors. Copper and sulfur compositions have pro-angiogenic functions by activating pro-angiogenic growth factors and promoting endothelial cells migration, growth, and tube formation. Thus, utilization of these elements may provide a unique opportunity to modulate angiogenesis under various setting. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Greenhouse effect of trace gases, 1970-1980
NASA Technical Reports Server (NTRS)
Lacis, A.; Hansen, J.; Lee, P.; Lebedeff, S.; Mitchell, T.
1981-01-01
Increased abundances were measured for several trace atmospheric gases in the decade 1970-1980. The equilibrium greenhouse warming for the measured increments of CH4, chlorofluorocarbons and N2O is between 50% and 100% of the equilibrium warming for the measured increase of atmospheric CO2 during the same 10 years. The combined warming of CO2 and trace gases should exceed natural global temperature variability in the 1980's and cause the global mean temperature to rise above the maximum of the late 1930's.
Oxidation of contaminative methane traces with radio-frequency discharge
NASA Technical Reports Server (NTRS)
Flamm, D. L.; Wydeven, T. L.
1976-01-01
An 11.8 MHz glow discharge was used to oxidize trace levels of methane in oxygen. The concentration of methane can be reduced by three orders of magnitude. The effects of power (0-400 W), flow rate (10-1000 cc-STP/min) and concentration (70-8000 ppm) were investigated at pressures ranging from 50 torr to almost 1 atm. No organic reaction products were detected in the treated gas stream. The process may prove useful for the removal of atmospheric trace contaminants at ambient pressure.
Bracken, Maeve; Rohrer, Nicole
2014-02-01
The current study assessed the effectiveness of an adapted form of the Picture Exchange Communication System (PECS) in increasing independent requesting in deafblind adults with learning disabilities. PECS cards were created to accommodate individual needs, including adaptations such as enlarging photographs and using swelled images which consisted of images created on raised line drawing paper. Training included up to Phase III of PECS and procedures ensuring generalizations across individuals and contexts were included. The effects of the intervention were evaluated using a multiple baseline design across participants. Results demonstrated an increase in independent requesting with each of the participants reaching mastery criterion. These results suggest that PECS, in combination with some minor adaptations, may be an effective communicative alternative for individuals who are deafblind and have learning impairments. Copyright © 2013 Elsevier Ltd. All rights reserved.
Wintemute, Garen J
2013-02-01
Firearms have widely supported legitimate purposes but are also frequently used in violent crimes. Owners and senior executives of federally licensed firearms dealers and pawnbrokers are a potentially valuable source of information on retail commerce in firearms, links between legal and illegal commerce, and policies designed to prevent the firearms they sell from being used in crimes. To our knowledge, there has been no prior effort to gather such information. In 2011, we conducted the Firearms Licensee Survey on a probability sample of 1,601 licensed dealers and pawnbrokers in the United States believed to sell 50 or more firearms per year. This article presents details of the design and execution of the survey and describes the characteristics of the respondents and their business establishments. The survey was conducted by mail, using methods developed by Dillman and others. Our response rate was 36.9 % (591 respondents), similar to that for other establishment surveys using similar methods. Respondents had a median age of 54; 89 % were male, 97.6 % were White, and 98.1 % were non-Hispanic. Those who held licenses under their own names had been licensed for a median of 18 years. A large majority of 96.3 % agreed that "private ownership of guns is essential for a free society"; just over half (54.9 %) believed that "it is too easy for criminals to get guns in this country." A match between the job and a personal interest in the shooting sports was the highest-ranking reason for working as a firearms retailer; the highest-ranking concerns were that "there are too many 'gun control' regulations" and that "the government might confiscate my guns." Most respondents (64.3 %) were gun dealers, with significant variation by region. Residential dealers accounted for 25.6 % of all dealers in the Midwest. Median annual sales volume was 200 firearms for both dealers and pawnbrokers. Dealers appeared more likely than pawnbrokers to specialize; they were more likely to rank in the highest or lowest quartile on sales of handguns, inexpensive handguns, and tactical rifles. Sales of inexpensive handguns and sales to women were more common among pawnbrokers. Internet sales were reported by 28.3 % of respondents and sales at gun shows by 14.3 %. A median of 1 % of sales were denied after purchasers failed background checks; firearm trace requests equaled <1 % of annual sales. Trace frequency was directly associated with the percentage of firearm sales involving handguns, inexpensive handguns, and sales to women. Frequency of denied sales was strongly and directly associated with frequency of trace requests (p < 0.0001). These results are based on self-report but are consistent with those from studies using objective data.
77 FR 70752 - Notice of Decision Regarding Requests for a Waiver of the Renewable Fuel Standard
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-27
...The Governors of several States requested that EPA waive the national volume requirements for the renewable fuel standard program (RFS or RFS program), pursuant to section 211(o)(7) of the Clean Air Act (the Act), based on the effects of the drought on feedstocks used to produce renewable fuel in 2012-2013. Several other parties submitted similar requests. Based on a thorough review of the record in this case, EPA finds that the evidence and information does not support a determination that implementation of the RFS program during the 2012- 2013 time period would severely harm the economy of a State, a region, or the United States. EPA is therefore denying the requests for a waiver.
Wasana, Hewa M S; Perera, Gamage D R K; Gunawardena, Panduka De S; Fernando, Palika S; Bandara, Jayasundera
2017-02-14
Despite WHO standards, waterborne diseases among the human being are rising alarmingly. It is known that the prolong exposure to contaminated water has major impact on public health. The effect of chemical contaminations in drinking water on human being is found to be chronic rather than acute and hence can be defined "consumption of contaminated drinking water could be a silent killer". As the WHO recommended water quality standards are only for individual element and synergic effects of trace metals and anions have not been considered, investigation of synergic effects of trace metals and anions and their effect on human being is of prime important research. By an animal trial, we investigated the synergic effect(s) of heavy metals, aluminium, arsenic, fluoride and hardness in drinking water on kidney tissues of mice. Our investigation strongly suggests existing of a synergic effect especially among Cd, F and hardness of water which could lead to severe kidney damage in mice, even at WHO maximum recommended levels. Hence, the synergic effect(s) of trace metals, fluoride and hardness present in drinking water should be investigated meticulously when stipulating the water quality at WHO maximum recommended levels.
NASA Astrophysics Data System (ADS)
Wasana, Hewa M. S.; Perera, Gamage D. R. K.; Gunawardena, Panduka De S.; Fernando, Palika S.; Bandara, Jayasundera
2017-02-01
Despite WHO standards, waterborne diseases among the human being are rising alarmingly. It is known that the prolong exposure to contaminated water has major impact on public health. The effect of chemical contaminations in drinking water on human being is found to be chronic rather than acute and hence can be defined “consumption of contaminated drinking water could be a silent killer”. As the WHO recommended water quality standards are only for individual element and synergic effects of trace metals and anions have not been considered, investigation of synergic effects of trace metals and anions and their effect on human being is of prime important research. By an animal trial, we investigated the synergic effect(s) of heavy metals, aluminium, arsenic, fluoride and hardness in drinking water on kidney tissues of mice. Our investigation strongly suggests existing of a synergic effect especially among Cd, F and hardness of water which could lead to severe kidney damage in mice, even at WHO maximum recommended levels. Hence, the synergic effect(s) of trace metals, fluoride and hardness present in drinking water should be investigated meticulously when stipulating the water quality at WHO maximum recommended levels.
77 FR 24494 - Agency Information Collection Request. 30-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-24
... their teaching of research integrity issues? (b) Will researchers use this DVD in future research... the effectiveness of an educational interactive video on research integrity--OMB No. 0990-New- Office of Research Integrity. Abstract: The Office of Research Integrity (ORI) proposes to conduct a web...
78 FR 54241 - Proposed Information Collection; Comment Request; BroadbandMatch Web Site Tool
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-03
... Information Collection; Comment Request; BroadbandMatch Web Site Tool AGENCY: National Telecommunications and... goal of increased broadband deployment and use in the United States. The BroadbandMatch Web site began... empowering technology effectively. II. Method of Collection BroadbandMatch users access the Web site through...
Evidence Based Education Request Desk. EBE #555
ERIC Educational Resources Information Center
Regional Educational Laboratory Southeast, 2009
2009-01-01
This Evidence Based Education (EBE) Request seeks to provide an overview of recent research regarding school improvement and reform with special concentration on turning around chronically low-performing schools. The response is divided into four main sections: Research on Effective Methods for Turning Around Low-Performing Schools, Frameworks for…
48 CFR 970.5227-9 - Notice of right to request patent waiver.
Code of Federal Regulations, 2010 CFR
2010-10-01
... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Solicitation Provisions and Contract Clauses for Management and Operating Contracts 970.5227-9 Notice of right to request patent waiver... contract, in advance of or within 30 days after the effective date of contracting. If such advance waiver...
48 CFR 970.5227-9 - Notice of right to request patent waiver.
Code of Federal Regulations, 2011 CFR
2011-10-01
... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Solicitation Provisions and Contract Clauses for Management and Operating Contracts 970.5227-9 Notice of right to request patent waiver... contract, in advance of or within 30 days after the effective date of contracting. If such advance waiver...
77 FR 18787 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-28
... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... having the intended effects, to evaluate the benefits and costs of changes in management measures, and to..., (202) 482-0336, Department of Commerce, Room 6616, 14th and Constitution Avenue NW., Washington, DC...
76 FR 12980 - Agency Information Collection Activities: Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-09
...) will publish periodic summaries of proposed projects. To request more information on the proposed... allowing SAMHSA to quantify the effects and accomplishments of SAMHSA programs. The following table is an...,000 .03 2,400 $18.40 $44,160 \\1\\ This table represents the maximum additional burden if adult...
77 FR 66951 - Proposed Information Collection; Comment Request; BIS Program Evaluation
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-08
... feedback from seminar participants. This information helps BIS determine the effectiveness of its programs... collection). Affected Public: Business or other for-profit organizations. Estimated Number of Respondents: 3... Total Annual Cost to Public: $0. IV. Request for Comments Comments are invited on: (a) Whether the...
75 FR 28550 - Proposed Information Collection; Comment Request; Delivery Verification Procedure
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-21
... the commodities shipped to the U.S. were in fact received. This procedure increases the effectiveness... Review: Regular submission. Affected Public: Business or other for-profit organizations. Estimated Number.... Estimated Total Annual Cost to Public: $0. IV. Request for Comments Comments are invited on: (a) Whether the...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-22
..., received. This procedure increases the effectiveness of controls on the international trade of strategic... collection). Affected Public: Business or other for-profit organizations. Estimated Number of Respondents... Annual Cost to Public: $0. IV. Request for Comments Comments are invited on: (a) Whether the proposed...
Teaching Children with Autism to Request Information
ERIC Educational Resources Information Center
Shillingsburg, M. Alice; Valentino, Amber L.; Bowen, Crystal N.; Bradley, Danielle; Zavatkay, Dana
2011-01-01
Question asking behavior, or requesting information, is often deficient in children with autism and can prove challenging to teach. Currently, there exists a paucity of research regarding the types of teaching strategies that are effective in teaching children with autism this crucial skill. The purpose of the present study was to examine…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-14
...; Tier 1 Screening of Certain Chemicals Under the Endocrine Disruptor Screening Program AGENCY... Chemicals; Tier 1 Screening of Certain Chemicals Under the Endocrine Disruptor Screening Program (EDSP... effects. The EDSP consists of a two-tiered approach to screen chemicals for potential endocrine disrupting...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-10
... Collection; Comment Request; Prohibited Species Donation (PSD) Program AGENCY: National Oceanic and... species donation (PSD) program for Pacific salmon and Pacific halibut has effectively reduced regulatory... distribution of salmon and halibut. The PSD program requires a collection-of-information so that NMFS can...
75 FR 10755 - Proposed Information Collection; Comment Request; 2010 NOAA Engagement Survey Tool
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-09
... Collection; Comment Request; 2010 NOAA Engagement Survey Tool AGENCY: National Oceanic and Atmospheric... effective two-way communication between its programs and the customers and clients it serves. This survey... parameters are three of the seven parameters included in the Kellogg Engagement Test, which the SAB...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-16
... measure their effectiveness. Through its voluntary Corporate Security Review (CSR) Program, TSA's Highway... DEPARTMENT OF HOMELAND SECURITY Transportation Security Administration Intent To Request Approval From OMB of One New Public Collection of Information: Security Program for Hazardous Materials Motor...
77 FR 21553 - Combined Notice of Filings #1
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-10
.... Description: Revisions to the PJM Tariff & OA re Lost Opportunity Cost for Wind to be effective 6/1/2012... Applicants: Twin Cities Power, LLC. Description: Twin Cities Power, LLC requests authorization under Section 203 of the Federal Power Act and Request for Expedited Consideration. Filed Date: 3/30/12. Accession...
75 FR 27345 - Agency Information Collection Request, 30-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-14
... to ensure effective integration of Federal public health and medical assets during an emergency. ASPR... DEPARTMENT OF HEALTH AND HUMAN SERVICES [Document Identifier: OS-0990-0344; 30-day notice] Agency... of the Secretary (OS), Department of Health and Human Services, is publishing the following summary...
50 CFR 216.104 - Submission of requests.
Code of Federal Regulations, 2010 CFR
2010-10-01
... requested (i.e., takes by harassment only; takes by harassment, injury and/or death) and the method of... technological) of equipment, methods, and manner of conducting such activity or other means of effecting the... similar significance; (12) Where the proposed activity would take place in or near a traditional Arctic...
76 FR 28987 - Agency Information Collection Request; 30-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-19
... diverse populations and clinical practice settings, that is, comparative effectiveness research (CER). The American Reinvestment and Recovery Act of 2009 (ARRA) expanded Federal resources devoted to CER by... also called for a report to Congress and the Secretary of HHS on priority CER topics by the Institute...
76 FR 59131 - Agency Information Collection Request; 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-23
... related to comparative effectiveness research (CER) funded by the American Recovery and Reinvestment Act... CER. Approximately 25% of the $400 million allocated to the Office of the Secretary for Health and... longitudinal data on health services financed by both public and private payers to help facilitate CER...
Report #09-N-0149, April 30, 2009. This is in response to a request dated April 24, 2009, asking that the EPA OIG provide information we have collected on the impact of the Rapanos case on Clean Water Act (CWA) enforcement.
77 FR 54652 - Draft Program Comment for Common Post-1945 Concrete and Steel Bridges
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-05
... Program Comment for Common Post-1945 Concrete and Steel Bridges AGENCIES: Federal Highway Administration... Bridges; request for comments. SUMMARY: The Advisory Council on Historic Preservation (ACHP) is... to the effects of undertakings on common post-1945 concrete and steel bridges. The FHWA is requesting...
75 FR 14158 - Agency Information Collection Request: 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-24
... reference the information collection's title, form, and OMB numbers (if any) in your comments. FOR FURTHER... of automated collection techniques or other forms of information technology to minimize the... have the foregoing adverse effects, the Commission may bring suit in the U.S. District Court for the...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yashchuk, Valeriy V.; Irick, Steve C.; MacDowell, Alastair A.
2005-04-28
A data acquisition technique and relevant program for suppression of one of the systematic effects, namely the ''ghost'' effect, of a second generation long trace profiler (LTP) is described. The ''ghost'' effect arises when there is an unavoidable cross-contamination of the LTP sample and reference signals into one another, leading to a systematic perturbation in the recorded interference patterns and, therefore, a systematic variation of the measured slope trace. Perturbations of about 1-2 {micro}rad have been observed with a cylindrically shaped X-ray mirror. Even stronger ''ghost'' effects show up in an LTP measurement with a mirror having a toroidal surfacemore » figure. The developed technique employs separate measurement of the ''ghost''-effect-related interference patterns in the sample and the reference arms and then subtraction of the ''ghost'' patterns from the sample and the reference interference patterns. The procedure preserves the advantage of simultaneously measuring the sample and reference signals. The effectiveness of the technique is illustrated with LTP metrology of a variety of X-ray mirrors.« less
The effect of direct-to-consumer advertising on prescription drug use by older adults.
Datti, Balaji; Carter, Mary W
2006-01-01
Although older adults are frequent consumers of prescription drugs and increasingly the intended audience of direct-to-consumer advertising (DTCA) marketing efforts, little is known about the effect of DTCA on older adults' prescription drug-seeking behaviour. In response, the objective of this study is to examine factors associated with requesting a prescription drug from a physician following exposure to DTCA among older adults, and whether the drug or other medical treatment was prescribed during the encounter. A secondary data analysis of the "Public Health Impact of Direct-to-Consumer Advertising of Prescription Drugs", a data set publicly available through the Inter-university Consortium for Political and Social Research (ICPSR 3687), was conducted. For the purposes of this study, only those respondents who indicated that they had been exposed to DTCA (n = 2601) were included in the study sample. Using a two-step weighted logistic regression approach, separate models were estimated to examine first, whether a request for the advertised drug was made following exposure to DTCA and secondly, the outcomes of any patient-physician encounters that occurred following exposure to DTCA. Descriptive analysis of the outcome variables revealed that, among respondents exposed to DTCA, 31% (n = 801) requested a prescription drug from their physician. Approximately 5% of those who made a request were > or =75 years of age. Among respondents requesting a prescription drug, 69% (n = 556) received a prescription in response to their request, of whom, approximately 5% were > or =75 years of age. Multivariate findings suggest that although adults > or =75 years of age are less likely to request a prescription drug following exposure to DTCA (odds ratio [OR] = 0.58; p = 0.032), when they do approach their physicians, they are more likely to receive recommendations for further treatment, with ORs indicating a 250% (OR = 3.507; p = 0.002) increase in the odds of further referral among adults > or =75 years of age. Overall, results from the study suggest that DTCA influences the patient-doctor relationship and prescription drug acquisition behaviour of patients; however, the nature of the effect of DTCA on older adults is complex. Because future cohorts of older adults may be more comfortable about requesting prescription drugs and the consumer-driven approach to obtaining medical care, understanding the impact of DTCA on older consumers represents an important area for further inquiry.
Investigation of Latent Traces Using Infrared Reflectance Hyperspectral Imaging
NASA Astrophysics Data System (ADS)
Schubert, Till; Wenzel, Susanne; Roscher, Ribana; Stachniss, Cyrill
2016-06-01
The detection of traces is a main task of forensics. Hyperspectral imaging is a potential method from which we expect to capture more fluorescence effects than with common forensic light sources. This paper shows that the use of hyperspectral imaging is suited for the analysis of latent traces and extends the classical concept to the conservation of the crime scene for retrospective laboratory analysis. We examine specimen of blood, semen and saliva traces in several dilution steps, prepared on cardboard substrate. As our key result we successfully make latent traces visible up to dilution factor of 1:8000. We can attribute most of the detectability to interference of electromagnetic light with the water content of the traces in the shortwave infrared region of the spectrum. In a classification task we use several dimensionality reduction methods (PCA and LDA) in combination with a Maximum Likelihood classifier, assuming normally distributed data. Further, we use Random Forest as a competitive approach. The classifiers retrieve the exact positions of labelled trace preparation up to highest dilution and determine posterior probabilities. By modelling the classification task with a Markov Random Field we are able to integrate prior information about the spatial relation of neighboured pixel labels.
Trace-element concentrations in streambed sediment across the conterminous United States
Rice, Karen C.
1999-01-01
Trace-element concentrations in 541 streambed-sediment samples collected from 20 study areas across the conterminous United States were examined as part of the National Water-Quality Assessment Program of the U.S. Geological Survey. Sediment samples were sieved and the <63-μm fraction was retained for determination of total concentrations of trace elements. Aluminum, iron, titanium, and organic carbon were weakly or not at all correlated with the nine trace elements examined: arsenic, cadmium, chromium, copper, lead, mercury, nickel, selenium, and zinc. Four different methods of accounting for background/baseline concentrations were examined; however, normalization was not required because field sieving removed most of the background differences between samples. The sum of concentrations of trace elements characteristic of urban settings - copper, mercury, lead, and zinc - was well correlated with population density, nationwide. Median concentrations of seven trace elements (all nine examined except arsenic and selenium) were enriched in samples collected from urban settings relative to agricultural or forested settings. Forty-nine percent of the sites sampled in urban settings had concentrations of one or more trace elements that exceeded levels at which adverse biological effects could occur in aquatic biota.
The role of high-energy synchrotron radiation in biomedical trace element research
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pounds, J.G.; Long, G.J.; Kwiatek, W.M.
1987-01-01
This paper will present the results of an investigation of the distribution of essential elements in the normal hepatic lobule. the liver is the organ responsible for metabolism and storage of most trace elements. Although parenchymal hepatocytes are rather uniform histologically, morphometry, histochemistry, immunohistochemistry, and microdissection with microchemical investigations have revealed marked heterogeneity on a functional and biochemical level. Hepatocytes from the periportal and perivenous zones of the liver parrenchyma differ in oxidative energy metabolism, glucose uptake and output, unreagenesis, biotransformation, bile acid secretion, and palsma protein synthesis and secretion. Although trace elements are intimately involved in the regulation andmore » maintenance of these functions, little is known regarding the heterogeneity of trace element localization of the liver parenchyma. Histochemical techniques for trace elements generally give high spatial resolution, but lack specificity and stoichiometry. Microdissection has been of marginal usefulness for trace element analyses due to the very small size of the dissected parenchyma. The characteristics of the high-energy x-ray microscope provide an effective approach for elucidating the trace element content of these small biological structures or regions. 5 refs., 1 fig., 1 tab.« less
Effect of supplemental trace mineral level and form on peripubertal bulls
USDA-ARS?s Scientific Manuscript database
The objectives were to determine if different supplemental trace mineral levels and /or forms (sulfate and metal amino acid complexes) influence age at puberty, semen quality, endocrine status and scrotal circumference in peripubertal bulls. Fifty crossbred, peripubertal bulls were blocked by age (...
NASA Astrophysics Data System (ADS)
Shi, Shengxian; Ding, Junfei; New, T. H.; Soria, Julio
2017-07-01
This paper presents a dense ray tracing reconstruction technique for a single light-field camera-based particle image velocimetry. The new approach pre-determines the location of a particle through inverse dense ray tracing and reconstructs the voxel value using multiplicative algebraic reconstruction technique (MART). Simulation studies were undertaken to identify the effects of iteration number, relaxation factor, particle density, voxel-pixel ratio and the effect of the velocity gradient on the performance of the proposed dense ray tracing-based MART method (DRT-MART). The results demonstrate that the DRT-MART method achieves higher reconstruction resolution at significantly better computational efficiency than the MART method (4-50 times faster). Both DRT-MART and MART approaches were applied to measure the velocity field of a low speed jet flow which revealed that for the same computational cost, the DRT-MART method accurately resolves the jet velocity field with improved precision, especially for the velocity component along the depth direction.
Electrostatic Discharge Effects on Thin Film Resistors
NASA Technical Reports Server (NTRS)
Sampson, Michael J.; Hull, Scott M.
1999-01-01
Recently, open circuit failures of individual elements in thin film resistor networks have been attributed to electrostatic discharge (ESD) effects. This paper will discuss the investigation that came to this conclusion and subsequent experimentation intended to characterize design factors that affect the sensitivity of resistor elements to ESD. The ESD testing was performed using the standard human body model simulation. Some of the design elements to be evaluated were: trace width, trace length (and thus width to length ratio), specific resistivity of the trace (ohms per square) and resistance value. However, once the experiments were in progress, it was realized that the ESD sensitivity of most of the complex patterns under evaluation was determined by other design and process factors such as trace shape and termination pad spacing. This paper includes pictorial examples of representative ESD failure sites, and provides some options for designing thin film resistors that are ESD resistant. The risks of ESD damage are assessed and handling precautions suggested.
NASA Astrophysics Data System (ADS)
Broekhuizen, K. E.; Thornberry, T.; Abbatt, J. P.
2003-12-01
The ability of organic aerosols to act as cloud condensation nuclei (CCN) will be discussed. A variety of laboratory experiments will be presented which address several key questions concerning organic particle activation. Does the particle phase impact activation? How does surface tension play a role and can a trace amount of a surface active species impact activation? Does a trace amount of a highly soluble species impact the activation of organic particles of moderate to low solubility? Can the activation properties of organic aerosols be enhanced through oxidative processing? To systematically address these issues, the CCN activity of various diacids such as oxalic, malonic, succinic, adipic and azelaic acid have been studied, as well as the addition of trace amounts of nonanoic acid and ammonium sulfate to examine the roles of surface active and soluble species, respectively. The first examination of the role of oxidative processing on CCN activity has involved investigating the effect of ozone oxidation on the activity of oleic acid particles.
Emotional expressions in voice and music: same code, same effect?
Escoffier, Nicolas; Zhong, Jidan; Schirmer, Annett; Qiu, Anqi
2013-08-01
Scholars have documented similarities in the way voice and music convey emotions. By using functional magnetic resonance imaging (fMRI) we explored whether these similarities imply overlapping processing substrates. We asked participants to trace changes in either the emotion or pitch of vocalizations and music using a joystick. Compared to music, vocalizations more strongly activated superior and middle temporal cortex, cuneus, and precuneus. However, despite these differences, overlapping rather than differing regions emerged when comparing emotion with pitch tracing for music and vocalizations, respectively. Relative to pitch tracing, emotion tracing activated medial superior frontal and anterior cingulate cortex regardless of stimulus type. Additionally, we observed emotion specific effects in primary and secondary auditory cortex as well as in medial frontal cortex that were comparable for voice and music. Together these results indicate that similar mechanisms support emotional inferences from vocalizations and music and that these mechanisms tap on a general system involved in social cognition. Copyright © 2011 Wiley Periodicals, Inc.
Li, Yuzhong; Tong, Huiling; Zhuo, Yuqun; Wang, Shujuan; Xu, Xuchang
2006-12-15
Sulfur dioxide (SO2) and trace elements are all pollutants derived from coal combustion. This study relates to the simultaneous removal of SO2 and trace selenium dioxide (SeO2) from flue gas by calcium oxide (CaO) adsorption in the moderate temperature range, especially the effect of SO2 presence on selenium capture. Experiments performed on a thermogravimetric analyzer (TGA) can reach the following conclusions. When the CaO conversion is relatively low and the reaction rate is controlled by chemical kinetics, the SO2 presence does not affect the selenium capture. When the CaO conversion is very high and the reaction rate is controlled by product layer diffusion, the SO2 presence and the product layer diffusion resistance jointly reduce the selenium capture. On the basis of the kinetics study, a method to estimate the trace selenium removal efficiency using kinetic parameters and the sulfur removal efficiency is developed.
Han, Hengda; Hu, Song; Syed-Hassan, Syed Shatir A; Xiao, Yiming; Wang, Yi; Xu, Jun; Jiang, Long; Su, Sheng; Xiang, Jun
2017-07-01
Sewage sludge is an important class of bioresources whose energy content could be exploited using pyrolysis technology. However, some harmful trace elements in sewage sludge can escape easily to the gas phase during pyrolysis, increasing the potential of carcinogenic material emissions to the atmosphere. This study investigates emission characteristics of arsenic, cadmium and lead under different pyrolysis conditions for three different sewage sludge samples. The increased temperature (within 723-1123K) significantly promoted the cadmium and lead emissions, but its influence on arsenic emission was not pronounced. The releasing rate order of the three trace elements is volatile arsenic compounds>cadmium>lead in the beginning of pyrolysis. Fast heating rates promoted the emission of trace elements for the sludge containing the highest amount of ash, but exhibited an opposite effect for other studied samples. Overall, the high ash sludge released the least trace elements almost under all reaction conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.
NASA Technical Reports Server (NTRS)
Keitz, E. L.
1978-01-01
Stratospheric trace constituent measurement requirements are separated into two somewhat overlapping areas. In the first area, it is assumed that the only problem of interest is ozone; its chemistry chain, environmental effects and measurement requirements. In like manner, in the second area it is assumed that the only problem of interest is stratospheric aerosols; their chemistry, effects and measurement requirements.
Mahmood, Shahid; Khalid, Azeem; Arshad, Muhammad; Ahmad, Riaz
2015-11-01
This study demonstrates the role of electron shuttles and trace metals in the biotransformation of azo dye reactive black-5 and hexavalent chromium (CrVI) that are released simultaneously in tannery effluent. Previously isolated bacterial strain Pseudomonas putida KI was used for the simultaneous reduction of the dye (100 mg L(-1)) and CrVI (2 mg L(-1)) in a mineral salts medium (MSM). Among various trace metals, only Cu(II) had a stimulating effect on the bacterial-mediated reduction process. Application of electron shuttles such as hydroquinone and uric acid at a low concentration (1mM) had a positive effect on the reduction process and caused simultaneous reduction of 100% dye and 97% CrVI in 12-18 h. Mannitol, EDTA and sodium benzoate at all concentrations (ranging from 1 to 9 mM) showed an inhibitory effect on the reduction of reactive black-5 and CrVI. An inverse linear relationship between the velocity of reaction (V) and the concentration [S] of electron shuttles was observed. The results imply that both types and concentration of an electron shuttle and trace metals can affect the simultaneous reduction of reactive black-5 and CrVI. Copyright © 2014 Elsevier Ltd. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Himmerkus, Felix; Rittmeyer, Cornelia
2012-07-01
The data management system KADABRA was designed according to the purposes of the Cen-tral Decontamination Department (HDB) of the Wiederaufarbeitungsanlage Karlsruhe Rueckbau- und Entsorgungs-GmbH (WAK GmbH), which is specialized in the treatment and conditioning of radioactive waste. The layout considers the major treatment processes of the HDB as well as regulatory and legal requirements. KADABRA is designed as an SAG ADABAS application on IBM system Z mainframe. The main function of the system is the data management of all processes related to treatment, transfer and storage of radioactive material within HDB. KADABRA records the relevant data concerning radioactive residues, interimmore » products and waste products as well as the production parameters relevant for final disposal. Analytical data from the laboratory and non destructive assay systems, that describe the chemical and radiological properties of residues, production batches, interim products as well as final waste products, can be linked to the respective dataset for documentation and declaration. The system enables the operator to trace the radioactive material through processing and storage. Information on the actual sta-tus of the material as well as radiological data and storage position can be gained immediately on request. A variety of programs accessed to the database allow the generation of individual reports on periodic or special request. KADABRA offers a high security standard and is constantly adapted to the recent requirements of the organization. (authors)« less
Kapoutsis, Ilias; Volkema, Roger; Lampaki, Antonia
2017-01-01
We undertook two vignette studies to examine the role of affect (trait and state) and bargaining power on initiating negotiations, an often overlooked stage of the negotiation process. Using a job negotiation opportunity, we examine three distinct phases of the initiation process—engaging a counterpart, making a request, and optimizing a request. Study 1 examines the effects of two affect dispositions (happiness and sadness), under power asymmetry (low vs. high bargaining power), on the three initiation behaviors. We found that power is pivotal to the decision to engage, request, and optimize. Also, sadness reduces the likelihood of initiation when power is high but is immaterial when power is low. In contrast, individuals who tend to be happy can reverse the adverse effect of powerlessness on requesting, but not on engaging and optimizing. However, happiness does not carry over a positive effect on negotiation initiation, over and above that of power. Study 2 investigated the role of trait affect when individuals are in power asymmetry and when they are induced with sadness or happiness. We found that those with a happy disposition initiate more (engage, request, and optimize) when power is high and experience incidental sadness. Overall, these findings qualify previous research on negotiation initiation and highlight the importance of trait affect and its interaction with state affect as additional driving forces and of power as a boundary condition. “for the error occurs at the beginning, and the beginning as the proverb says is half of the whole, so that even a small mistake at the beginning stands in the same ratio to mistakes at the other stages.” (trans. Aristotle, 1944, 1303b) PMID:28824496
Kapoutsis, Ilias; Volkema, Roger; Lampaki, Antonia
2017-01-01
We undertook two vignette studies to examine the role of affect (trait and state) and bargaining power on initiating negotiations, an often overlooked stage of the negotiation process. Using a job negotiation opportunity, we examine three distinct phases of the initiation process-engaging a counterpart, making a request, and optimizing a request. Study 1 examines the effects of two affect dispositions (happiness and sadness), under power asymmetry (low vs. high bargaining power), on the three initiation behaviors. We found that power is pivotal to the decision to engage, request, and optimize. Also, sadness reduces the likelihood of initiation when power is high but is immaterial when power is low. In contrast, individuals who tend to be happy can reverse the adverse effect of powerlessness on requesting, but not on engaging and optimizing. However, happiness does not carry over a positive effect on negotiation initiation, over and above that of power. Study 2 investigated the role of trait affect when individuals are in power asymmetry and when they are induced with sadness or happiness. We found that those with a happy disposition initiate more (engage, request, and optimize) when power is high and experience incidental sadness. Overall, these findings qualify previous research on negotiation initiation and highlight the importance of trait affect and its interaction with state affect as additional driving forces and of power as a boundary condition. " for the error occurs at the beginning, and the beginning as the proverb says is half of the whole, so that even a small mistake at the beginning stands in the same ratio to mistakes at the other stages. " (trans. Aristotle, 1944 , 1303b) .
Effects of dietary amines on the gut and its vasculature.
Broadley, Kenneth J; Akhtar Anwar, M; Herbert, Amy A; Fehler, Martina; Jones, Elen M; Davies, Wyn E; Kidd, Emma J; Ford, William R
2009-06-01
Trace amines, including tyramine and beta-phenylethylamine (beta-PEA), are constituents of many foods including chocolate, cheeses and wines and are generated by so-called 'friendly' bacteria such as Lactobacillus, Lactococcus and Enterococcus species, which are found in probiotics. We therefore examined whether these dietary amines could exert pharmacological effects on the gut and its vasculature. In the present study we examined the effects of tyramine and beta-PEA on the contractile activity of guinea-pig and rat ileum and upon the isolated mesenteric vasculature and other blood vessels. Traditionally, these amines are regarded as sympathomimetic amines, exerting effects through the release of noradrenaline from sympathetic nerve endings, which should relax the gut. A secondary aim was therefore to confirm this mechanism of action. However, contractile effects were observed in the gut and these were independent of noradrenaline, acetylcholine, histamine and serotonin receptors. They were therefore probably due to the recently described trace amine-associated receptors. These amines relaxed the mesenteric vasculature. In contrast, the aorta and coronary arteries were constricted, a response that was also independent of a sympathomimetic action. From these results, we propose that after ingestion, trace amines could stimulate the gut and improve intestinal blood flow. Restriction of blood flow elsewhere diverts blood to the gut to aid digestion. Thus, trace amines in the diet may promote the digestive process through stimulation of the gut and improved gastrointestinal circulation.
Long-term anaerobic digestion of food waste stabilized by trace elements.
Zhang, Lei; Jahng, Deokjin
2012-08-01
The purpose of this study was to examine if long-term anaerobic digestion of food waste in a semi-continuous single-stage reactor could be stabilized by supplementing trace elements. Contrary to the failure of anaerobic digestion of food waste alone, stable anaerobic digestion of food waste was achieved for 368 days by supplementing trace elements. Under the conditions of OLR (organic loading rates) of 2.19-6.64 g VS (volatile solid)/L day and 20-30 days of HRT (hydraulic retention time), a high methane yield (352-450 mL CH(4)/g VS(added)) was obtained, and no significant accumulation of volatile fatty acids was observed. The subsequent investigation on effects of individual trace elements (Co, Fe, Mo and Ni) showed that iron was essential for maintaining stable methane production. These results proved that the food waste used in this study was deficient in trace elements. Copyright © 2012. Published by Elsevier Ltd.
Stratospheric H2O and HNO3 profiles derived from solar occultation measurements
NASA Technical Reports Server (NTRS)
Fischer, H.; Fergg, F.; Rabus, D.; Burkert, P.
1985-01-01
Compact two-channel radiometers for solar occultation experiments have been constructed in order to measure stratospheric trace gases. The instruments can be used as filter- or correlation-type radiometers, depending on the trace gas under investigation. Within the LIMS correlative measurement program, balloon flights were performed with a payload of up to four of these two-channel radiometers. From the filter-type measurements, profiles of the trace gases H2O and HNO3 are inferred for the height region between the tropopause and the balloon float level. The data evaluation also includes a comprehensive analysis of the error sources and their effect on the accuracy of the trace gas profiles. The derived H2O and HNO3 profiles are assessed against the observations of other authors and are discussed in the light of the trace gas distributions calcualted from photochemical models.
Evaluating progressive-rendering algorithms in appearance design tasks.
Jiawei Ou; Karlik, Ondrej; Křivánek, Jaroslav; Pellacini, Fabio
2013-01-01
Progressive rendering is becoming a popular alternative to precomputational approaches to appearance design. However, progressive algorithms create images exhibiting visual artifacts at early stages. A user study investigated these artifacts' effects on user performance in appearance design tasks. Novice and expert subjects performed lighting and material editing tasks with four algorithms: random path tracing, quasirandom path tracing, progressive photon mapping, and virtual-point-light rendering. Both the novices and experts strongly preferred path tracing to progressive photon mapping and virtual-point-light rendering. None of the participants preferred random path tracing to quasirandom path tracing or vice versa; the same situation held between progressive photon mapping and virtual-point-light rendering. The user workflow didn’t differ significantly with the four algorithms. The Web Extras include a video showing how four progressive-rendering algorithms converged (at http://youtu.be/ck-Gevl1e9s), the source code used, and other supplementary materials.
Process Upsets Involving Trace Contaminant Control Systems
NASA Technical Reports Server (NTRS)
Graf, John C.; Perry, Jay; Wright, John; Bahr, Jim
2000-01-01
Paradoxically, trace contaminant control systems that suffer unexpected upsets and malfunctions can release hazardous gaseous contaminants into a spacecraft cabin atmosphere causing potentially serious toxicological problems. Trace contaminant control systems designed for spaceflight typically employ a combination of adsorption beds and catalytic oxidation reactors to remove organic and inorganic trace contaminants from the cabin atmosphere. Interestingly, the same design features and attributes which make these systems so effective for purifying a spacecraft's atmosphere can also make them susceptible to system upsets. Cabin conditions can be contributing causes of phenomena such as adsorbent "rollover" and catalyst poisoning can alter a systems performance and in some in stances release contamination into the cabin. Evidence of these phenomena has been observed both in flight and during ground-based tests. The following discussion describes specific instances of system upsets found in trace contaminant control systems, groups these specific upsets into general hazard classifications, and recommends ways to minimize these hazards.
The Forensic Confirmation Bias: A Comparison Between Experts and Novices.
van den Eeden, Claire A J; de Poot, Christianne J; van Koppen, Peter J
2018-05-17
A large body of research has described the influence of context information on forensic decision-making. In this study, we examined the effect of context information on the search for and selection of traces by students (N = 36) and crime scene investigators (N = 58). Participants investigated an ambiguous mock crime scene and received prior information indicating suicide, a violent death or no information. Participants described their impression of the scene and wrote down which traces they wanted to secure. Results showed that context information impacted first impression of the scene and crime scene behavior, namely number of traces secured. Participants in the murder condition secured most traces. Furthermore, the students secured more crime-related traces. Students were more confident in their first impression. This study does not indicate that experts outperform novices. We therefore argue for proper training on cognitive processes as an integral part of all forensic education. © 2018 American Academy of Forensic Sciences.
Alexander, Jonathan T; Hai, Faisal I; Al-Aboud, Turki M
2012-11-30
Trace organic contaminants have become an increasing cause of concern for governments and water authorities as they attempt to respond to the potential challenges posed by climate change by implementing sustainable water cycle management practices. The augmentation of potable water supplies through indirect potable water reuse is one such method currently being employed. Given the uncertainty surrounding the potential human health impacts of prolonged ingestion of trace organic contaminants, it is vital that effective and sustainable treatment methods are utilized. The purpose of this article is to provide a comprehensive literature review of the performance of the chemical coagulation process in removing trace organic contaminants from water. This study evaluated the removal data collated from recent research relating to various trace organic contaminants during the coagulation process. It was observed that there is limited research data relating to the removal of trace organic contaminants using coagulation. The findings of this study suggest that there is a gap in the current research investigating the potential of new types of coagulants and exploring coagulation-based hybrid processes to remove trace organic contaminants from water. The data analysed in this study regarding removal efficiency suggests that, even for the significantly hydrophobic compounds, hydrophobicity is not the sole factor governing removal of trace organic contaminants by coagulation. This has important implications in that the usual practice of screening coagulants based on turbidity (suspended solid) removal proves inadequate in the case of trace organic contaminant removal. Copyright © 2012 Elsevier Ltd. All rights reserved.
Trace element profiles of the sea anemone Anemonia viridis living nearby a natural CO2 vent
Borell, Esther M.; Fine, Maoz; Shaked, Yeala
2014-01-01
Ocean acidification (OA) is not an isolated threat, but acts in concert with other impacts on ecosystems and species. Coastal marine invertebrates will have to face the synergistic interactions of OA with other global and local stressors. One local factor, common in coastal environments, is trace element contamination. CO2 vent sites are extensively studied in the context of OA and are often considered analogous to the oceans in the next few decades. The CO2 vent found at Levante Bay (Vulcano, NE Sicily, Italy) also releases high concentrations of trace elements to its surrounding seawater, and is therefore a unique site to examine the effects of long-term exposure of nearby organisms to high pCO2 and trace element enrichment in situ. The sea anemone Anemonia viridis is prevalent next to the Vulcano vent and does not show signs of trace element poisoning/stress. The aim of our study was to compare A. viridis trace element profiles and compartmentalization between high pCO2 and control environments. Rather than examining whole anemone tissue, we analyzed two different body compartments—the pedal disc and the tentacles, and also examined the distribution of trace elements in the tentacles between the animal and the symbiotic algae. We found dramatic changes in trace element tissue concentrations between the high pCO2/high trace element and control sites, with strong accumulation of iron, lead, copper and cobalt, but decreased concentrations of cadmium, zinc and arsenic proximate to the vent. The pedal disc contained substantially more trace elements than the anemone’s tentacles, suggesting the pedal disc may serve as a detoxification/storage site for excess trace elements. Within the tentacles, the various trace elements displayed different partitioning patterns between animal tissue and algal symbionts. At both sites iron was found primarily in the algae, whereas cadmium, zinc and arsenic were primarily found in the animal tissue. Our data suggests that A. viridis regulates its internal trace element concentrations by compartmentalization and excretion and that these features contribute to its resilience and potential success at the trace element-rich high pCO2 vent. PMID:25250210
Recent trends in the variability of halogenated trace gases over the United States
NASA Astrophysics Data System (ADS)
Hurst, Dale F.; Bakwin, Peter S.; Elkins, James W.
1998-10-01
Recent trends in the atmospheric variability of seven halogenated trace gases are determined from three years (November 1994 through October 1997) of hourly gas chromatographic measurements at a 610 m tower in North Carolina and 17 months (June 1996 through October 1997) of similar measurements at a 450 m tower in Wisconsin. Production of five of these gases, CCl3F (CFC-11), CCl2F2 (CFC-12), CCl2FCClF2 (CFC-113), CH3CCl3 (methyl chloroform), and CCl4 (carbon tetrachloride), is now strictly regulated in the United States and other developed countries under international legislation. C2Cl4 (tetrachloroethene) and SF6 (sulfur hexafluoride) are currently produced without restriction, but requests for voluntary cutbacks in C2Cl4 emissions have been made, at least in the United States. Atmospheric variability of these gases is examined at several sampling heights on the towers, but trends are deduced using only nighttime data at the top sampling level of each tower to minimize variability driven by local emissions and the diurnal cycle of the planetary boundary layer, leaving regional emissions as the main source of day-to-day variability. Significant downward trends are determined for CFC-12, CFC-113, CH3CCl3, and C2Cl4 variability at both towers, reflecting decreased emissions of these gases in two regions of the United States. Trends in CFC-11, CCl4, and SF6 variability at both towers are not significantly different from zero.
Tracing a roadmap for vitamin B₁₂ testing using the health technology assessment approach.
Ferraro, Simona; Mozzi, Roberta; Panteghini, Mauro
2014-06-01
In our hospital, we are currently working to manage the appropriateness of vitamin B₁₂ (B12) testing. Unfortunately, the classic evidence-based approach is unhelpful in this process and meta-analyzing data on the accuracy of this marker for cobalamin deficiency detection is misleading due to the lack of reference diagnostic methods. The approach currently proposed by the Health Technology Assessment (HTA) enables us to tackle the issue of B₁₂ requests as a "healthcare" problem by considering the position of stakeholders involved in ordering, performing, interpreting the test, and receiving its results. Clinical expectations, methodological issues, and ethical aspects concerning the performance of the test can aid us in providing more guidance on the use of this marker. By building such structured information, hemodialysis patients and pregnant women have emerged as those groups preferentially requiring B₁₂ testing, as it may potentially improve the clinical outcome. To avoid misinterpretation of B₁₂ results more care should be taken in considering its biochemical and biological features, as well as the analytical issues. Spurious values obtained by current automated immunoassays may reflect suboptimal pre-analytical steps as well as known interfering conditions. Furthermore, the harmonization of results by available methods is still a far-reaching goal and the approach to interpret an individual's results should be improved. Tracing a roadmap for B₁₂ testing by exploiting the HTA model to balance the stakeholders' claims and maximizing the patient's outcome may help to manage the marker demand.
Dietary trace amine-dependent vasoconstriction in porcine coronary artery
Herbert, A A; Kidd, E J; Broadley, K J
2008-01-01
Background and purpose: The dietary trace amines tyramine and β-phenylethylamine (β-PEA) can increase blood pressure. However, the mechanisms involved in the vascular effect of trace amines have not been fully established. The purpose of this study was to evaluate whether trace amine-dependent vasoconstriction was brought about by tyramine and β-PEA acting as indirect sympathomimetic agents, as previously assumed, or whether trace amine-dependent vasoconstriction could be mediated by recently discovered trace amine-associated (TAA) receptors. Experimental approach: The responses to p-tyramine and β-PEA were investigated in vitro in rings of the left anterior descending coronary arteries of pigs. Key results: p-Tyramine induced a concentration-dependent (0.1–3 mM) vasoconstriction. The maximum response and pD2 value for p-tyramine was unaffected by endothelium removal or pre-treatment with antagonists for adrenoceptors, histamine, dopamine or 5-HT receptors. β-PEA also produced a concentration-dependent (0.3–10 mM) vasoconstriction which was unaffected by endothelium removal, β-adrenoceptor or 5-HT receptor antagonists. A substantial, but reduced, response to β-PEA was obtained in the presence of prazosin (α1-adrenoceptor antagonist), haloperidol (D2/D3 dopamine receptor antagonist) or mepyramine (H1 histamine receptor antagonist). The pD2 value for β-PEA was unaffected by any of the antagonists tested. Conclusions and implications: Vasoconstriction induced by p-tyramine does not involve an indirect sympathomimetic effect, although vasoconstriction caused by β-PEA may occur, in part, by this mechanism. We therefore propose that trace amine-dependent vasoconstriction is mediated by phenylethylamine-specific receptors, which are closely related to or identical to TAA receptors. These receptors could provide a target for new antihypertensive therapies. PMID:18604230
Sensitivity of trace element pyritization to pyrite oxidation processes
NASA Astrophysics Data System (ADS)
Moreira, Manuel; Díaz, Rut; Mendoza, Ursula; Capilla, Ramses; Böttcher, Michael; Luiza Albuquerque, Ana; Machado, Wilson
2014-05-01
Total trace elements concentration variability in marine sediments has been widely used as a proxy for redox conditions and marine paleoprodutivity. However, partial extraction procedures reduce influences of detrital sedimentary fractions, and information on trace element geochemical partitioning can contribute to provide comprehensive evidences on elemental sensitivity to particular processes. The potential effect of sedimentary pyrite re-oxidative cycling on the degree of trace metal pyritization (DTMP) has not been previously evaluated. This study investigates this effect in 4 sediment cores from the continental shelf under the influence of a tropical upwelling system (Cabo Frio, Brazil). The relation of DTMP with stable isotope signals (δ34SCRS) of chromium reducible sulfur, which becomes lighter in response to intense pyrite re-oxidative cycling in the study area, suggests high (As, Cd and Mn), low (Cu and Zn) or negligible (Cr and Ni) re-oxidation influences. The oldest, pyrite-richer sediments provide an apparent threshold for intense pyrite re-oxidation, after which most trace elements (As, Cd, Zn and Mn) presented more accentuated pyritization. A middle shelf core presented negative correlations of reactive (HCl-soluble) Mn, Cu and Ni with pyrite iron, suggesting Mn oxide (and associated metals) depletion in reaction with pyrite. Results provided evidences for coupled influences from both aerobic and anaerobic oxidative processes on trace elements incorporation into pyrite. Pyrite δ34S signatures under the oxic bottom water from the study area were similar to those from euxinic sedimentary environments, suggesting that pyrite re-oxidative cycling can affect trace element susceptibility to be incorporated and preserved into pyrite in a wide range of sedimentary conditions. The evaluation of trace elements sensitivity to these processes can contribute to improve the use of multiple DTMP data (e.g., as paleoredox proxies). Considering that S re-oxidative cycling is ubiquitous in many sedimentary conditions, such coupled use of DTMP and δ34SCRS proxies can be possibly applied to a large variety of sedimentary environments.
[The reproducibility of multifocal ERG recordings].
Meigen, T; Friedrich, A
2002-09-01
Multifocal electroretinogram recordings (mfERG) can be used to detect a local dysfunction of the retina. In this study we tested both the intrasessional and inter-sessional reproducibility of mfERG amplitudes. MfERGs from 6 eyes of 6 normal subjects were recorded on two different days using DTL electrodes. The relative coefficient of variation ( RCV) was used to quantify the amplitude reproducibility. We tested the effect of (a) session (inter- vs. intrasessional), (b) recording duration (7.3 vs. 3.6 min), (c) trace type (hexagon traces vs. ring averages), and (d) amplitude definition (peak-trough analysis vs. scalar product) on RCV. RCV was 6.5+/-0.4% (Mean+/-SEM, n=96) when averaged across all recording conditions and all subjects. The ANOVA showed a significant difference ( p=0.018) between hexagon traces and ring averages. Another significant effect ( p=0.016) occurred for the interaction of (a) and (b). MfERGs can be recorded with a high degree of reproducibility even for short recording durations and single hexagon traces. As the factor (a) did not show a significant effect, the new placement of the DTL electrode in the second session does not necessarily increase the retest variability compared to a second recording within the same session.
Effects of Cabin Upsets on Adsorption Columns for Air Revitalization
NASA Technical Reports Server (NTRS)
LeVan, Douglas
1999-01-01
The National Aeronautics and Space Administration (NASA) utilizes adsorption technology as part of contaminant removal systems designed for long term missions. A variety of trace contaminants can be effectively removed from gas streams by adsorption onto activated carbon. An activated carbon adsorption column meets NASA's requirements of a lightweight and efficient means of controlling trace contaminant levels aboard spacecraft and space stations. The activated carbon bed is part of the Trace Contaminant Control System (TCCS) which is utilized to purify the cabin atmosphere. TCCS designs oversize the adsorption columns to account for irregular fluctuations in cabin atmospheric conditions. Variations in the cabin atmosphere include changes in contaminant concentrations, temperature, and relative humidity. Excessively large deviations from typical conditions can result from unusual crew activity, equipment malfunctions, or even fires. The research carried out under this award focussed in detail on the effects of cabin upsets on the performance of activated carbon adsorption columns. Both experiments and modeling were performed with an emphasis on the roll of a change in relative humidity on adsorption of trace contaminants. A flow through fixed-bed apparatus was constructed at the NASA Ames Research Center, and experiments were performed there. Modeling work was performed at the University of Virginia.
Image Tracing: An Analysis of Its Effectiveness in Children's Pictorial Discrimination Learning
ERIC Educational Resources Information Center
Levin, Joel R.; And Others
1977-01-01
A total of 45 fifth grade students were the subjects of an experiment offering support for a component of learning strategy (memory imagery). Various theoretical explanations of the image-tracing phenomenon are considered, including depth of processing, dual coding and frequency. (MS)
Seeking the Trace of Argumentation in Turkish Science Curriculum
ERIC Educational Resources Information Center
Cetin, Pinar Seda; Metin, Duygu; Capkinoglu, Esra; Leblebicioglu, Gulsen
2016-01-01
Providing students with inquiry-oriented learning environments is a major concern in science education. Argumentation discourse can enhance the effectiveness of inquiry-oriented learning environments. This study seeks the trace of argumentation in Turkish Elementary and Secondary Science Curriculum developed by the Turkish Ministry of Education…
Jiang, Zhi-quan; Hu, Ke-liang
2016-03-01
In the field of forensic science, conventional infrared spectral analysis technique is usually unable to meet the detection requirements, because only very a few trace material evidence with diverse shapes and complex compositions, can be extracted from the crime scene. Infrared microscopic technique is developed based on a combination of Fourier-transform infrared spectroscopic technique and microscopic technique. Infrared microscopic technique has a lot of advantages over conventional infrared spectroscopic technique, such as high detection sensitivity, micro-area analysisand nondestructive examination. It has effectively solved the problem of authentication of trace material evidence in the field of forensic science. Additionally, almost no external interference is introduced during measurements by infrared microscopic technique. It can satisfy the special need that the trace material evidence must be reserved for witness in court. It is illustrated in detail through real case analysis in this experimental center that, infrared microscopic technique has advantages in authentication of trace material evidence in forensic science field. In this paper, the vibration features in infrared spectra of material evidences, including paints, plastics, rubbers, fibers, drugs and toxicants, can be comparatively analyzed by means of infrared microscopic technique, in an attempt to provide powerful spectroscopic evidence for qualitative diagnosis of various criminal and traffic accident cases. The experimental results clearly suggest that infrared microscopic technique has an incomparable advantage and it has become an effective method for authentication of trace material evidence in the field of forensic science.
Physician-assisted deaths under the euthanasia law in Belgium: a population-based survey.
Chambaere, Kenneth; Bilsen, Johan; Cohen, Joachim; Onwuteaka-Philipsen, Bregje D; Mortier, Freddy; Deliens, Luc
2010-06-15
Legalization of euthanasia and physician-assisted suicide has been heavily debated in many countries. To help inform this debate, we describe the practices of euthanasia and assisted suicide, and the use of life-ending drugs without an explicit request from the patient, in Flanders, Belgium, where euthanasia is legal. We mailed a questionnaire regarding the use of life-ending drugs with or without explicit patient request to physicians who certified a representative sample (n = 6927) of death certificates of patients who died in Flanders between June and November 2007. The response rate was 58.4%. Overall, 208 deaths involving the use of life-ending drugs were reported: 142 (weighted prevalence 2.0%) were with an explicit patient request (euthanasia or assisted suicide) and 66 (weighted prevalence 1.8%) were without an explicit request. Euthanasia and assisted suicide mostly involved patients less than 80 years of age, those with cancer and those dying at home. Use of life-ending drugs without an explicit request mostly involved patients 80 years of older, those with a disease other than cancer and those in hospital. Of the deaths without an explicit request, the decision was not discussed with the patient in 77.9% of cases. Compared with assisted deaths with the patient's explicit request, those without an explicit request were more likely to have a shorter length of treatment of the terminal illness, to have cure as a goal of treatment in the last week, to have a shorter estimated time by which life was shortened and to involve the administration of opioids. Physician-assisted deaths with an explicit patient request (euthanasia and assisted suicide) and without an explicit request occurred in different patient groups and under different circumstances. Cases without an explicit request often involved patients whose diseases had unpredictable end-of-life trajectories. Although opioids were used in most of these cases, misconceptions seem to persist about their actual life-shortening effects.
Effects of dopamine D1 modulation of the anterior cingulate cortex in a fear conditioning procedure
Pezze, M.A.; Marshall, H.J.; Domonkos, A.; Cassaday, H.J.
2016-01-01
The anterior cingulate cortex (AC) component of the medial prefrontal cortex (mPFC) has been implicated in attention and working memory as measured by trace conditioning. Since dopamine (DA) is a key modulator of mPFC function, the present study evaluated the role of DA receptor agents in rat AC, using trace fear conditioning. A conditioned stimulus (CS, noise) was followed by an unconditioned stimulus (US, shock) with or without a 10 s trace interval interposed between these events in a between-subjects design. Conditioned suppression of drinking was assessed in response to presentation of the CS or an experimental background stimulus (flashing lights, previously presented for the duration of the conditioning session). The selective D1 agonist SKF81297 (0.05 μg/side) or D1 antagonist SCH23390 (0.5 μg/side) was administered by intra-cerebral microinfusion directly into AC. It was predicted that either of these manipulations should be sufficient to impair trace (but not delay) conditioning. Counter to expectation, there was no effect of DA D1 modulation on trace conditioning as measured by suppression to the noise CS. However, rats infused with SKF81297 acquired stronger conditioned suppression to the experimental background stimulus than those infused with SCH23390 or saline. Thus, the DA D1 agonist SKF81297 increased conditioned suppression to the contextual background light stimulus but was otherwise without effect on fear conditioning. PMID:26343307
Madejón, P; Xiong, J; Cabrera, F; Madejón, E
2014-11-01
The use of fast growing trees could be an alternative in trace element contaminated soils to stabilize these elements and improve soil quality. In this study we investigate the effect of Paulownia fortunei growth on trace element contaminated soils amended with two organic composts under semi-field conditions for a period of 18 months. The experiment was carried out in containers filled with tree different soils, two contaminated soils (neutral AZ and acid V) and a non contaminated soil, NC. Three treatments per soil were established: two organic amendments (alperujo compost, AC, and biosolid compost, BC) and a control without amendment addition. We study parameters related with fertility and contamination in soils and plants. Paulownia growth and amendments increased pH in acid soils whereas no effect of these factors was observed in neutral soils. The plant and the amendments also increased organic matter and consequently, soil fertility. Positive results were also found in soils that were only affected by plant growth (without amendment). A general improvement of "soil biochemical quality" was detected over time and treatments, confirming the positive effect of amendments plus paulownia. Even in contaminated soils, except for Cu and Zn, trace element concentrations in leaves were in the normal range for plants. Results of this mid-term study showed that Paulownia fortunei is a promising species for phytoremediation of trace element polluted soils. Copyright © 2014 Elsevier Ltd. All rights reserved.
Ran, Jing; Wang, Dejian; Wang, Can; Zhang, Gang; Yao, Lipeng
2014-08-01
Portable X-ray fluorescence (PXRF) spectrometry may be very suitable for a fast and effective environmental assessment and source identification of trace metals in soils. In this study, topsoils (0-10 cm) at 139 sites were in situ scanned for total trace metals (Cr, Cu, Ni, Pb and Zn) and arsenic concentrations by PXRF in a typical town in Yangtze Delta region of Jiangsu province, China. To validate the utility of PXRF, 53 samples were collected from the scanning sites for the determination of selected trace metals using conventional methods. Based on trace metal concentrations detected by in situ PXRF, the contamination extent and sources of trace metals were studied via geo-accumulation index, multivariate analysis and geostatistics. The trace metal concentrations determined by PXRF were similar to those obtained via conventional chemical analysis. The median concentration of As, Cr, Cu, Ni, Pb and Zn in soils were 10.8, 56.4, 41.5, 43.5, 33.5, and 77.7 mg kg(-1), respectively. The distribution patterns of Cr, Cu, Ni, Pb, and Zn were mostly affected by anthropogenic sources, while As was mainly derived from lithogenic sources. Overall, PXRF has been successfully applied to contamination assessment and source identification of trace metals in soils.
Schmidt, Thomas; McCabe, Bernadette K; Harris, Peter W; Lee, Seonmi
2018-05-18
In this study, anaerobic digestion of slaughterhouse wastewater with the addition of trace elements was monitored for biogas quantity, quality and process stability using CSTR digesters operated at mesophilic temperature. The determination of trace element concentrations was shown to be deficient in Fe, Ni, Co, Mn and Mo compared to recommendations given in the literature. Addition of these trace elements resulted in enhanced degradation efficiency, higher biogas production and improved process stability. Higher organic loading rates and lower hydraulic retention times were achieved in comparison to the control digesters. A critical accumulation of volatile fatty acids was observed at an organic loading rate of 1.82 g L -1 d -1 in the control compared to 2.36 g L -1 d -1 in the digesters with trace element addition. The improved process stability was evident in the final weeks of experimentation, in which control reactors produced 84% less biogas per day compared to the reactors containing trace elements. Copyright © 2018 Elsevier Ltd. All rights reserved.
Li, Feng; Lin, Ze-Feng; Wen, Jia-Sheng; Wei, Yan-Sha; Gan, Hua-Yang; He, Hai-Jun; Lin, Jin-Qin; Xia, Zhen; Chen, Bi-Shuang; Guo, Wen-Jie; Tan, Cha-Sheng; Cai, Hua-Yang
2017-12-15
Hainan Island is the second largest island and one of the most famous tourist destinations in China, but sediment contamination by trace metals in coastal areas is a major issue. However, full-scale risk assessments of trace metal-polluted coastal sediments are lacking. In this study, coastal surface sediments from 474 geographical locations covering almost the entire island were collected to identify risk-related variables. Controlling factors and possible sources of trace metals were identified, and the toxicity effects were carefully evaluated. Our results suggest that trace-metal pollution in coastal sediments, which was mainly caused by Pb, Zn and Cu emissions, has primarily resulted from industrial sewage and shipping activities and has threatened the offshore ecosystem of Hainan Island and warrants extensive consideration. This is the first study that has systematically investigated trace metal-polluted coastal sediments throughout the entirety of Hainan Island and provides solid evidence for sustainable marine management in the region. Copyright © 2017 Elsevier Ltd. All rights reserved.
Accumulated energy norm for full waveform inversion of marine data
NASA Astrophysics Data System (ADS)
Shin, Changsoo; Ha, Wansoo
2017-12-01
Macro-velocity models are important for imaging the subsurface structure. However, the conventional objective functions of full waveform inversion in the time and the frequency domain have a limited ability to recover the macro-velocity model because of the absence of low-frequency information. In this study, we propose new objective functions that can recover the macro-velocity model by minimizing the difference between the zero-frequency components of the square of seismic traces. Instead of the seismic trace itself, we use the square of the trace, which contains low-frequency information. We apply several time windows to the trace and obtain zero-frequency information of the squared trace for each time window. The shape of the new objective functions shows that they are suitable for local optimization methods. Since we use the acoustic wave equation in this study, this method can be used for deep-sea marine data, in which elastic effects can be ignored. We show that the zero-frequency components of the square of the seismic traces can be used to recover macro-velocities from synthetic and field data.
Chang, Lin; Bi, Pengyu; Li, Xiaochen; Wei, Yun
2015-06-15
A novel trace analytical method based on solvent sublation (SS) and gas chromatography-mass spectrometry (GC-MS) was developed for the trace determination of twenty-two phthalate esters (PAEs) from plastic beverage packaging. In the solvent sublation section, the effects of solution pH, NaCl concentration, nitrogen flow rate, and sublation time on the sublation efficiency were investigated in detail, and the optimal conditions were obtained. The trace PAEs migrated from plastic beverage packaging to food simulants were separated and concentrated by solvent sublation, and then the trace target compounds in the concentrated solution were analyzed by GC-MS. According to the European Union Regulation, the food simulants including distilled water for the normal beverages and acetic acid solution (3%) for the acetic beverage of yogurt were prepared for migration tests. The trace analysis method showed good linearity, low limits of detection (LODs) of 1.6-183.5 ng/L, and satisfied recoveries (67.3-113.7%). Copyright © 2015 Elsevier Ltd. All rights reserved.
Trace elements: implications for nursing.
Hayter, J
1980-01-01
Although most were unknown a few years ago, present evidence indicates that at least 25 trace elements have some pertinence to health. Unlike vitamins, they cannot be synthesized. Some trace elements are now considered important only because of their harmful effects but traces of them may be essential. Zinc is especially important during puberty, pregnancy and menopause and is related to protein metabolism. Both fluoride and cadmium accumulate in the body year after year. Cadmium is positively correlated with several chronic diseases, especially hypertension. It is obtained from smoking and drinking soft water. Silicon, generally associated with silicosis, may be necessary for healthy bone and connective tissue. Chromium, believed to be the glucose tolerance factor, is obtained from brewer's yeast, spices, and whole wheat products. Copper deficiency may be implicated in a wide range of cardiovascular and blood related disorders. Either marginal deficiencies or slight excesses of most trace elements are harmful. Nurses should instruct patients to avoid highly refined foods, fad diets, or synthetic and fabricated foods. A well balanced and varied diet is the best safeguard against trace element excesses or deficiencies.
Contribution of finger tracing to the recognition of Chinese characters.
Yim-Ng, Y Y; Varley, R; Andrade, J
2000-01-01
Finger tracing is a simulation of the act of writing without the use of pen and paper. It is claimed to help in the processing of Chinese characters, possibly by providing additional motor coding. In this study, blindfolded subjects were equally good at identifying Chinese characters and novel visual stimuli through passive movements made with the index finger of the preferred hand and those made with the last finger of that hand. This suggests that finger tracing provides a relatively high level of coding specific to individual characters, but non-specific to motor effectors. Beginning each stroke from the same location, i.e. removing spatial information, impaired recognition of the familiar characters and the novel nonsense figures. Passively tracing the strokes in a random sequence also impaired recognition of the characters. These results therefore suggest that the beneficial effect of finger tracing on writing or recall of Chinese characters is mediated by sequence and spatial information embedded in the motor movements, and that proprioceptive channel may play a part in mediating visuo-spatial information. Finger tracing may be a useful strategy for remediation of Chinese language impairments.
ERIC Educational Resources Information Center
Alt, Mary; Spaulding, Tammie
2011-01-01
Purpose: The purpose of this study was to measure the effect of time to response in a fast-mapping word learning task for children with specific language impairment (SLI) and children with typically developing language skills (TD). Manipulating time to response allows us to examine decay of the memory trace, the use of vocal rehearsal, and their…
Trinity Bay Study: Dye tracing experiments
NASA Technical Reports Server (NTRS)
Ward, G. H., Jr.
1972-01-01
An analysis of the heat balance and temperature distribution within Trinity Bay near Galveston, Texas is presented. The effects of tidal currents, wind driven circulations, and large volume inflows are examined. Emphasis is placed on the effects of turbulent diffusion and local shears in currents. The technique of dye tracing to determine the parameters characterizing dispersion is described. Aerial photographs and maps are provided to show the flow conditions existing at different times and seasons.
System for Secure Integration of Aviation Data
NASA Technical Reports Server (NTRS)
Kulkarni, Deepak; Wang, Yao; Keller, Rich; Chidester, Tom; Statler, Irving; Lynch, Bob; Patel, Hemil; Windrem, May; Lawrence, Bob
2007-01-01
The Aviation Data Integration System (ADIS) of Ames Research Center has been established to promote analysis of aviation data by airlines and other interested users for purposes of enhancing the quality (especially safety) of flight operations. The ADIS is a system of computer hardware and software for collecting, integrating, and disseminating aviation data pertaining to flights and specified flight events that involve one or more airline(s). The ADIS is secure in the sense that care is taken to ensure the integrity of sources of collected data and to verify the authorizations of requesters to receive data. Most importantly, the ADIS removes a disincentive to collection and exchange of useful data by providing for automatic removal of information that could be used to identify specific flights and crewmembers. Such information, denoted sensitive information, includes flight data (here signifying data collected by sensors aboard an aircraft during flight), weather data for a specified route on a specified date, date and time, and any other information traceable to a specific flight. The removal of information that could be used to perform such tracing is called "deidentification." Airlines are often reluctant to keep flight data in identifiable form because of concerns about loss of anonymity. Hence, one of the things needed to promote retention and analysis of aviation data is an automated means of de-identification of archived flight data to enable integration of flight data with non-flight aviation data while preserving anonymity. Preferably, such an automated means would enable end users of the data to continue to use pre-existing data-analysis software to identify anomalies in flight data without identifying a specific anomalous flight. It would then also be possible to perform statistical analyses of integrated data. These needs are satisfied by the ADIS, which enables an end user to request aviation data associated with de-identified flight data. The ADIS includes client software integrated with other software running on flight-operations quality-assurance (FOQA) computers for purposes of analyzing data to study specified types of events or exceedences (departures of flight parameters from normal ranges). In addition to ADIS client software, ADIS includes server hardware and software that provide services to the ADIS clients via the Internet (see figure). The ADIS server receives and integrates flight and non-flight data pertaining to flights from multiple sources. The server accepts data updates from authorized sources only and responds to requests from authorized users only. In order to satisfy security requirements established by the airlines, (1) an ADIS client must not be accessible from the Internet by an unauthorized user and (2) non-flight data as airport terminal information system (ATIS) and weather data must be displayed without any identifying flight information. ADIS hardware and software architecture as well as encryption and data display scheme are designed to meet these requirements. When a user requests one or more selected aviation data characteristics associated with an event (e.g., a collision, near miss, equipment malfunction, or exceedence), the ADIS client augments the request with date and time information from encrypted files and submits the augmented request to the server. Once the user s authorization has been verified, the server returns the requested information in de-identified form.
Perceptual chunking and its effect on memory in speech processing: ERP and behavioral evidence
Gilbert, Annie C.; Boucher, Victor J.; Jemel, Boutheina
2014-01-01
We examined how perceptual chunks of varying size in utterances can influence immediate memory of heard items (monosyllabic words). Using behavioral measures and event-related potentials (N400) we evaluated the quality of the memory trace for targets taken from perceived temporal groups (TGs) of three and four items. Variations in the amplitude of the N400 showed a better memory trace for items presented in TGs of three compared to those in groups of four. Analyses of behavioral responses along with P300 components also revealed effects of chunk position in the utterance. This is the first study to measure the online effects of perceptual chunks on the memory trace of spoken items. Taken together, the N400 and P300 responses demonstrate that the perceptual chunking of speech facilitates information buffering and a processing on a chunk-by-chunk basis. PMID:24678304
Perceptual chunking and its effect on memory in speech processing: ERP and behavioral evidence.
Gilbert, Annie C; Boucher, Victor J; Jemel, Boutheina
2014-01-01
We examined how perceptual chunks of varying size in utterances can influence immediate memory of heard items (monosyllabic words). Using behavioral measures and event-related potentials (N400) we evaluated the quality of the memory trace for targets taken from perceived temporal groups (TGs) of three and four items. Variations in the amplitude of the N400 showed a better memory trace for items presented in TGs of three compared to those in groups of four. Analyses of behavioral responses along with P300 components also revealed effects of chunk position in the utterance. This is the first study to measure the online effects of perceptual chunks on the memory trace of spoken items. Taken together, the N400 and P300 responses demonstrate that the perceptual chunking of speech facilitates information buffering and a processing on a chunk-by-chunk basis.
Semi-volatile organic compounds and trace elements in the Yangtze River source of drinking water.
Wu, Bing; Zhang, Xuxiang; Zhang, Xiaolin; Yasun, Aishangjiang; Zhang, Yan; Zhao, Dayong; Ford, Tim; Cheng, Shupei
2009-08-01
Determination of 24 semi-volatile organic compounds (SVOCs) and 24 trace elements in water samples was conducted in order to investigate the quality of the Nanjing source of drinking water taken from Yangtze River. The total concentrations of SVOCs and trace elements were in the range of 1,951-11,098 ng/l and 51,274-72,384 microg/l, respectively. No significant seasonal changes were found for the pollutants' concentrations. A primary health risk assessment was carried out to evaluate potential health effects. Risk quotients involving carcinogenic effects for benzo(a)anthracene, benzo(a)pyrene, benzo(b)fluoranthene, dibenz(a,h)anthracene, bis(2-ethylhexyl)phthalate and arsenic were >1 under the worst-case scenario. The results of this study demonstrate the importance of further studies on the environmental health effects of exposure to the source water.
The Effect of Grammatical Accuracy and Gender on Interlanguage Request Strategy
ERIC Educational Resources Information Center
Sanjaya, I. Nyoman Suka; Sitawati, Anak Agung Raka
2017-01-01
The present study was aimed at examining whether grammatical accuracy and gender were significant predictors of the use of request strategy (direct or indirect). Participants were 39 seventh semester students (29 males and 10 females) majoring in an International Business Management program at a public higher education institution in Bali. Their…
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75 FR 6208 - Proposed Collection; Comment Request; Web Based Training for Pain Management Providers
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26 CFR 1.6050H-0 - Table of contents.
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..., 1989. (i) Failure to file return or to furnish statement. (ii) Failure to furnish TIN. (iii) Failure to...) Failure to furnish TIN. (iii) Failure to include correct information. (f) Requirement to request and to obtain TIN. (1) In general. (2) Manner of requesting TIN. (g) Effective date. (1) In general. (2) Points...
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Video Modeling to Teach Social Safety Skills to Young Adults with Intellectual Disability
ERIC Educational Resources Information Center
Spivey, Corrine E.; Mechling, Linda C.
2016-01-01
This study evaluated the effectiveness of video modeling with a constant time delay procedure to teach social safety skills to three young women with intellectual disability. A multiple probe design across three social safety skills (responding to strangers who: requested personal information; requested money; and entered the participant's…
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77 FR 75157 - Notice of Receipt of a Request To Voluntarily Cancel Certain Pesticide Registrations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-19
... Rodenticide Act (FIFRA), as amended, EPA is issuing a notice of receipt of request by registrants to... the cancellation for the allethrins end-use products will be effective December 31, 2016, as described... and Sumitomo Chemical Company Limited to cancel all their allethrins pesticide products registered...
10 CFR 205.374 - Responses from “entities” designated in the application.
Code of Federal Regulations, 2011 CFR
2011-01-01
... analysis of the impact the requested action would have on its system reliability and its ability to supply its own interruptible and firm customers. The effects of the requested action on the ability to serve firm loads shall be clearly distinguished from the ability to serve contractually interruptible loads...
10 CFR 205.374 - Responses from “entities” designated in the application.
Code of Federal Regulations, 2013 CFR
2013-01-01
... analysis of the impact the requested action would have on its system reliability and its ability to supply its own interruptible and firm customers. The effects of the requested action on the ability to serve firm loads shall be clearly distinguished from the ability to serve contractually interruptible loads...
10 CFR 205.374 - Responses from “entities” designated in the application.
Code of Federal Regulations, 2012 CFR
2012-01-01
... analysis of the impact the requested action would have on its system reliability and its ability to supply its own interruptible and firm customers. The effects of the requested action on the ability to serve firm loads shall be clearly distinguished from the ability to serve contractually interruptible loads...
10 CFR 205.374 - Responses from “entities” designated in the application.
Code of Federal Regulations, 2014 CFR
2014-01-01
... analysis of the impact the requested action would have on its system reliability and its ability to supply its own interruptible and firm customers. The effects of the requested action on the ability to serve firm loads shall be clearly distinguished from the ability to serve contractually interruptible loads...
76 FR 53902 - Agency Information Collection Request. 30-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-30
... performance of the agency's functions; (2) the accuracy of the estimated burden; (3) ways to enhance the... Health and the Centers for Disease Control and Prevention (CDC) are working collaboratively to address the high pregnancy rate of women between the ages of 15-19 by demonstrating the effectiveness of...
24 CFR 970.15 - Specific criteria for HUD approval of demolition requests.
Code of Federal Regulations, 2010 CFR
2010-04-01
... HOUSING PROJECTS § 970.15 Specific criteria for HUD approval of demolition requests. (a) In addition to... public housing project must certify that the project: (1) Is obsolete as to physical condition, location... modifications is cost-effective to return the public housing project or portion of the project to useful life...
76 FR 6793 - Agency Information Collection Request. 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-08
..., that is, comparative effectiveness research (CER). The American Reinvestment and Recovery Act of 2009 (ARRA) expanded Federal resources devoted to CER by directing $1.1 billion to the U.S. Department of... Secretary of HHS on priority CER topics by the Institute of Medicine (IOM). The report presented priority...
75 FR 15749 - Entergy Operations, Inc., Grand Gulf Nuclear Station, Unit 1; Exemption
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-30
... request to extend the rule's compliance date for all operating nuclear power plants, but noted that the... (Nuclear Energy Institute) dated June 4, 2009. The licensee's request for an exemption is therefore...) now or hereafter in effect. The facility consists of a boiling-water reactor located in Claiborne...
75 FR 16869 - Entergy Nuclear Operations, LLC; Palisades Nuclear Plant; Exemption
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-02
... generic industry request to extend the rule's compliance date for all operating nuclear power plants, but..., to M. S. Fertel, Nuclear Energy Institute). The licensee's request for an exemption is therefore... exemption will not have a significant effect on the quality of the human environment [75 FR 14473; dated...
75 FR 11947 - STP Nuclear Operating Company, South Texas Project, Units 1 and 2; Exemption
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
... request to extend the rule's compliance date for all operating nuclear power plants, but noted that the..., Nuclear Energy Institute). The licensee's request for an exemption is therefore consistent with the.... Nuclear Regulatory Commission (NRC, the Commission) now or hereafter in effect. The facility consists of...
50 CFR 660.312 - Vessel Monitoring System (VMS) requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... his/her vessel by sending a written request to NMFS OLE specifying the following information: The... requested; and the location of the vessel while the exemption is in effect. NMFS OLE will issue a written... submitted, initial contact with NMFS OLE must be made by telephone, fax or email within 24 hours from when...
78 FR 38335 - Agency Information Collection Request; 60-Day Public Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-26
... title, form, and OMB numbers (if any) in your comments. FOR FURTHER INFORMATION CONTACT: To obtain... techniques or other forms of information technology to minimize the information collection burden... adverse effects, the Commission may bring suit in the U.S. District Court for the District of Columbia to...
12 CFR 261a.7 - Special procedures for medical records.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Special procedures for medical records. 261a.7... Requests by Individual to Whom Record Pertains § 261a.7 Special procedures for medical records. Medical or... physician, have an adverse effect upon the requester. Upon such determination, the information shall be...
ERIC Educational Resources Information Center
Grunzeweig, Naomi; Stack, Dale M.; Serbin, Lisa A.; Ledingham, Jane; Schwartzman, Alex E.
2009-01-01
This prospective, intergenerational study investigated the influences of maternal histories of childhood aggression and social withdrawal on maternal request strategies and child compliance and noncompliance. Seventy-four women from the Concordia Longitudinal Risk Project, who were rated during childhood using peer nomination measures of…
Software solutions alone cannot guarantee useful radiology requests.
Van Borsel, Mathias D; Devolder, Pieter Jd; Bosmans, Jan Ml
2016-11-01
Background The availability of clinical information and a pertinent clinical question can improve the diagnostic accuracy of the imaging process. Purpose To examine if an electronic request form forcing referring clinicians to provide separate input of both clinical information and a clinical question can improve the quality of the request. Material and Methods A total of 607 request forms in the clinical worklists for a computed tomography (CT) scan of the thorax, the abdomen or their combination, were examined. Using software of our own making, we examined the presence of clinical information and a clinical question before and after the introduction of a new, more compelling order method. We scored and compared the quality of the clinical information and the clinical question between the two systems and we examined the effect on productivity. Results Both clinical information and a clinical question were present in 76.7% of cases under the old system and in 95.3% under the new system ( P < 0.001). Individual characteristics of the clinical information and the clinical question however, with the exception of incompleteness, showed little improvement under the new system. There was also no significant difference between the two systems in the number of requests requiring further search. Conclusion The introduction of electronic radiology request forms compelling referring clinicians to provide separate input of clinical information and a clinical question provides only limited benefit to the quality of the request. Raising awareness among clinicians of the importance of a well-written request remains essential.
Utsunomiya, Satoshi; Jensen, Keld A; Keeler, Gerald J; Ewing, Rodney C
2004-04-15
Exposure to airborne particulates containing low concentrations of heavy metals, such as Pb, As, and Se, may have serious health effects. However, little is known about the speciation and particle size of these airborne metals. Fine- and ultrafine particles with heavy metals in aerosol samples from the Detroit urban area, Michigan, were examined in detail to investigate metal concentrations and speciation. The characterization of individual particles was completed using high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) combined with conventional high-resolution TEM techniques. The trace elements, Pb, As, La, Ce, Sr, Zn, Cr, Se, Sn, Y, Zr, Au, and Ag, were detected, and the elemental distributions were mapped in situ atthe nanoscale. The crystal structures of the particles containing Pb, Sr, Zn, and Au were determined from their electron diffraction patterns. Based on the characterization of the representative trace element particles, the potential health effects are discussed. Most of the trace element particles detected in this study were within a range of 0.01-1.0 microm in size, which has the longest atmospheric residence time (approximately 100 days). Increased chemical reactivity owing to the size of nanoparticles may be expected for most of the trace metal particles observed.
Chebassier, Nathalie; El Houssein, Ouijja; Viegas, Isabelle; Dréno, Brigitte
2004-08-01
Matrix metalloproteinase (MMP)-2 and MMP-9 are involved in keratinocyte migration and granulation tissue remodeling during wound healing. Thermal water cures are sometimes proposed as complementary treatment for accelerating healing of wounds resulting from burns and/or surgery, but their mechanisms of action remain unknown. Some thermal waters are rich in trace elements such as boron and manganese. Interestingly, clinical studies have shown the beneficial effects of trace elements such as boron and manganese for human wound healing. To try to specify the role of trace elements in cutaneous healing, the present study investigated the effects of these trace elements on the production of MMP-2 and MMP-9 by normal human keratinocytes cultured in vitro. Immunohistochemistry and Western blot showed that intracellular MMP-9 expression in keratinocytes was induced when incubated for 6 h with boron at 10 micro g/ml or manganese at 0.2 micro g/ml. Moreover, gelatin zymography on keratinocyte supernatants showed an increase of gelatinase secretion after 24 h of incubation of keratinocytes with boron or manganese, regardless of concentration. Gelatinase secretion was not associated with keratinocyte proliferation induced by trace elements. Thus, our results suggest that boron and manganese could play a role in the clinical efficiency of thermal water on wound healing.
Leuner, Benedetta; Waddell, Jaylyn; Gould, Elizabeth; Shors, Tracey J.
2012-01-01
Some, but not all, types of learning and memory can influence neurogenesis in the adult hippocampus. Trace eyeblink conditioning has been shown to enhance the survival of new neurons, whereas delay eyeblink conditioning has no such effect. The key difference between the two training procedures is that the conditioning stimuli are separated in time during trace but not delay conditioning. These findings raise the question of whether temporal discontiguity is necessary for enhancing the survival of new neurons. Here we used two approaches to test this hypothesis. First, we examined the influence of a delay conditioning task in which the duration of the conditioned stimulus (CS) was increased nearly twofold, a procedure that critically engages the hippocampus. Although the CS and unconditioned stimulus are contiguous, this very long delay conditioning procedure increased the number of new neurons that survived. Second, we examined the influence of learning the trace conditioned response (CR) after having acquired the CR during delay conditioning, a procedure that renders trace conditioning hippocampal-independent. In this case, trace conditioning did not enhance the survival of new neurons. Together, these results demonstrate that associative learning increases the survival of new neurons in the adult hippocampus, regardless of temporal contiguity. PMID:17192426
Locality in Search Engine Queries and Its Implications for Caching
2001-05-01
in the question of whether caching might be effective for search engines as well. They study two real search engine traces by examining query...locality and its implications for caching. The two search engines studied are Vivisimo and Excite. Their trace analysis results show that queries have
Determining trace gas flux from container-grown woody ornamentals
USDA-ARS?s Scientific Manuscript database
In recent years, anthropogenic climate change and its effects on the global environment has garnered significant attention from the scientific community. Increased trace gas emissions (CO2, CH4, and N2O) are widely believed to be the driving force behind global warming. Agriculture is a large contri...
Tracing the French Policy PISA Debate: A Policy Configuration Approach
ERIC Educational Resources Information Center
Pons, Xavier
2016-01-01
This article traces the evolution of the French policy PISA debate from 2001 to 2014 by analysing the results of two original qualitative researches. Theoretically, this debate is the outcome of specific policy configurations, which predetermine its scope, content and effectiveness. These configurations are themselves described through their…
USDA-ARS?s Scientific Manuscript database
Soil microbes dominate processes that regulate soil trace gas emissions and soil C and N dynamics. Intensive management in agroecosystems provides unique opportunities to assess the effectiveness of microbial manipulations to enhance soil C retention and reduce trace gas emissions. While reduced til...
Irrigation and fertilizer placement effects on trace gas emissions from an ornamental crop
USDA-ARS?s Scientific Manuscript database
Agriculture is a large contributor of trace gas emissions and much of the work on reducing greenhouse gas (GHG) emissions has focused on row crops, pastures, forestry, and animal production systems; however, little emphasis has been placed on specialty crop industries such as horticulture. A horticu...
Interleaved Practice with Multiple Representations: Analyses with Knowledge Tracing Based Techniques
ERIC Educational Resources Information Center
Rau, Martina A.; Pardos, Zachary A.
2012-01-01
The goal of this paper is to use Knowledge Tracing to augment the results obtained from an experiment that investigated the effects of practice schedules using an intelligent tutoring system for fractions. Specifically, this experiment compared different practice schedules of multiple representations of fractions: representations were presented to…
Trace contaminant studies of HSC adsorbent. M.S. Thesis
NASA Technical Reports Server (NTRS)
Yieh, D. T. N.
1978-01-01
The adsorption and desorption of fifteen trace contaminants on HSC (polyethylenimine coated acrylic ester) adsorbent were experimentally investigated with the following two objectives: to test the removal potential and the adsorption reversibility of the selected trace contaminants, and to test the effect a preadsorbed trace contaminant has on the CO2 adsorption capacity. The experimental method for acquiring the adsorption equilibrium data used is based on the volumetric (or displacement) concept of vacuum adsorption. From the experimental results, it was found that the HSC adsorbent has good adsorption potential for contaminants of alcohol compounds, esters, and benzene compounds; whereas, adsorption of ketone compounds, oxidizing and reducing agents are detrimental to the adsorbent. In addition, all liquid contaminants reduce the CO2 capacity of HSC adsorbent.
Hanauer, David A; Hruby, Gregory W.; Fort, Daniel G.; Rasmussen, Luke V.; Mendonça, Eneida A.; Weng, Chunhua
2014-01-01
Many academic medical centers have aggregated data from multiple clinical systems into centralized repositories. These repositories can then be queried by skilled data analysts who act as intermediaries between the data stores and the research teams. To obtain data, researchers are often expected to complete a data request form. Such forms are meant to support record-keeping and, most importantly, provide a means for conveying complex data needs in a clear and understandable manner. Yet little is known about how data request forms are constructed and how effective they are likely to be. We conducted a content analysis of ten data request forms from CTSA-supported institutions. We found that most of the forms over-emphasized the collection of metadata that were not considered germane to the actual data needs. Based on our findings, we provide recommendations to improve the quality of data request forms in support of clinical and translational research. PMID:25954367
Cooperation in Human-Agent Systems to Support Resilience: A Microworld Experiment.
Chiou, Erin K; Lee, John D
2016-09-01
This study uses a dyadic approach to understand human-agent cooperation and system resilience. Increasingly capable technology fundamentally changes human-machine relationships. Rather than reliance on or compliance with more or less reliable automation, we investigate interaction strategies with more or less cooperative agents. A joint-task microworld scenario was developed to explore the effects of agent cooperation on participant cooperation and system resilience. To assess the effects of agent cooperation on participant cooperation, 36 people coordinated with a more or less cooperative agent by requesting resources and responding to requests for resources in a dynamic task environment. Another 36 people were recruited to assess effects following a perturbation in their own hospital. Experiment 1 shows people reciprocated the cooperative behaviors of the agents; a low-cooperation agent led to less effective interactions and less resource sharing, whereas a high-cooperation agent led to more effective interactions and greater resource sharing. Experiment 2 shows that an initial fast-tempo perturbation undermined proactive cooperation-people tended to not request resources. However, the initial fast tempo had little effect on reactive cooperation-people tended to accept resource requests according to cooperation level. This study complements the supervisory control perspective of human-automation interaction by considering interdependence and cooperation rather than the more common focus on reliability and reliance. The cooperativeness of automated agents can influence the cooperativeness of human agents. Design and evaluation for resilience in teams involving increasingly autonomous agents should consider the cooperative behaviors of these agents. © 2016, Human Factors and Ergonomics Society.
Gregory, Philip J; Jalloh, Mohamed A; Abe, Andrew M; Hu, James; Hein, Darren J
2016-12-01
To characterize requests received through an academic drug information consultation service related to complementary and alternative medicines. A retrospective review and descriptive analysis of drug information consultations was conducted. A total of 195 consultations related to complementary and alternative medicine were evaluated. All consultation requests involved questions about dietary supplements. The most common request types were related to safety and tolerability (39%), effectiveness (38%), and therapeutic use (34%). Sixty-eight percent of the requests were from pharmacists. The most frequent consultation requests from pharmacists were questions related to drug interactions (37%), therapeutic use (37%), or stability/compatibility/storage (34%). Nearly 60% of complementary and alternative medicine-related consultation requests were able to be completely addressed using available resources. Among review sources, Natural Medicines Comprehensive Database, Clinical Pharmacology, Micromedex, and Pharmacist's Letter were the most common resources used to address consultations. Utilization of a drug information service may be a viable option for health care professionals to help answer a complementary and alternative medicine-related question. Additionally, pharmacists and other health care professionals may consider acquiring resources identified to consistently answering these questions. © The Author(s) 2015.
NASA Astrophysics Data System (ADS)
Chabot, N. L.
2017-12-01
As planetesimals were heated up in the early Solar System, the formation of Fe-Ni metallic melts was a common occurrence. During planetesimal differentiation, the denser Fe-Ni metallic melts separated from the less dense silicate components, though some meteorites suggest that their parent bodies only experienced partial differentiation. If the Fe-Ni metallic melts did form a central metallic core, the core eventually crystallized to a solid, some of which we sample as iron meteorites. In all of these planetesimal evolution processes, the composition of the Fe-Ni metallic melt influenced the process and the resulting trace element chemical signatures. In particular, the metallic melt's "light element" composition, those elements present in the metallic melt in a significant concentration but with lower atomic masses than Fe, can strongly affect trace element partitioning. Experimental studies have provided critical data to determine the effects of light elements in Fe-Ni metallic melts on trace element partitioning behavior. Here I focus on combining numerous experimental results to identify trace elements that provide unique insight into constraining the light element composition of early Solar System Fe-Ni metallic melts. Experimental studies have been conducted at 1 atm in a variety of Fe-Ni systems to investigate the effects of light elements on trace element partitioning behavior. A frequent experimental examination of the effects of light elements in metallic systems involves producing run products with coexisting solid metal and liquid metal phases. Such solid-metal-liquid-metal experiments have been conducted in the Fe-Ni binary system as well as Fe-Ni systems with S, P, and C. Experiments with O-bearing or Si-bearing Fe-Ni metallic melts do not lend themselves to experiments with coexisting solid metal and liquid metal phases, due to the phase diagrams of these elements, but experiments with two immiscible Fe-Ni metallic melts have provided insight into the qualitative effects of O and Si relative to the well-determined effects of S. Together, these experimental studies provide a robust dataset to identify key elements that are predicted to produce distinct chemical signatures as a function of different Fe-Ni metallic melt compositions during planetesimal evolution processes.
Metaheuristics for the dynamic stochastic dial-a-ride problem with expected return transports.
Schilde, M; Doerner, K F; Hartl, R F
2011-12-01
The problem of transporting patients or elderly people has been widely studied in literature and is usually modeled as a dial-a-ride problem (DARP). In this paper we analyze the corresponding problem arising in the daily operation of the Austrian Red Cross. This nongovernmental organization is the largest organization performing patient transportation in Austria. The aim is to design vehicle routes to serve partially dynamic transportation requests using a fixed vehicle fleet. Each request requires transportation from a patient's home location to a hospital (outbound request) or back home from the hospital (inbound request). Some of these requests are known in advance. Some requests are dynamic in the sense that they appear during the day without any prior information. Finally, some inbound requests are stochastic. More precisely, with a certain probability each outbound request causes a corresponding inbound request on the same day. Some stochastic information about these return transports is available from historical data. The purpose of this study is to investigate, whether using this information in designing the routes has a significant positive effect on the solution quality. The problem is modeled as a dynamic stochastic dial-a-ride problem with expected return transports. We propose four different modifications of metaheuristic solution approaches for this problem. In detail, we test dynamic versions of variable neighborhood search (VNS) and stochastic VNS (S-VNS) as well as modified versions of the multiple plan approach (MPA) and the multiple scenario approach (MSA). Tests are performed using 12 sets of test instances based on a real road network. Various demand scenarios are generated based on the available real data. Results show that using the stochastic information on return transports leads to average improvements of around 15%. Moreover, improvements of up to 41% can be achieved for some test instances.
Gao, Yang; Hao, Zhuo; Yang, Tiantian; He, Nianpeng; Tian, Jing; Wen, Xuefa
2016-10-01
In order to better understand air pollution in deve-loping regions, such as China, it is important to investigate the wet deposition behavior of atmospheric trace metals and its sources in the subtropical watershed. This paper studies the seasonal change of trace metal concentrations in precipitation and other potential sources in a typical subtropical watershed (Jiazhuhe watershed) located in the downstream of the Yangtze River of China. The results show that typical crustal elements (Al, Fe) and trace element (Zn) have high seasonal variation patterns and these elements have higher contents in precipitation as compared to other metals in Jiazhuhe watershed. In addition, there is no observed Pb in base flow in this study, and the concentration magnitudes of Al, Ba, Fe, Mn, Sr, and Zn in base flow are significantly higher than that of other metals. During different rainfall events, the dynamic export processes are also different for trace metals. The various trace metals dynamic export processes lead to an inconsistent mass first flush and a significant accumulative variance throughout the rainfall events. It is found that in this region, most of the trace metals in precipitation are from anthropogenic emission and marine aerosols brought by typhoon and monsoon.
NASA Astrophysics Data System (ADS)
Maeno, Tsuyoshi; Ueyama, Hiroya; Iida, Michihira; Fujiwara, Osamu
It is well known that electromagnetic disturbances in vehicle-mounted radios are mainly caused by conducted noise currents flowing through wiring-harnesses from vehicle-mounted printed circuit boards (PCBs) with common ground patterns with slits. To suppress the noise current outflows from the PCBs of this kind, we previously measured noise current outflows from simple two-layer PCBs having two parallel signal traces and different ground patterns with/without slits, which revealed that making slits with open ends on the ground patterns in parallel with the traces can reduce the conducted noise currents. In the present study, with the FDTD simulation, we investigated reduction characteristics of the FM-band cross-talk noise levels between two parallel signal traces for eighteen PCBs, which have different ground patterns with/without slits parallel to the traces and dielectric layers with different thickness. As a result, we found that the cross-talk reduction effect due to slits is obtained by 3.6-5.3dB, while the cross-talks between signal traces are reduced in inverse proportion to the square of the dielectric-layer thickness and in proportion to the square of the trace interval and, which can quantitatively be explained from an inductive coupling theory.
Mohr, Oliver; Hermes, Julia; Schink, Susanne B; Askar, Mona; Menucci, Daniel; Swaan, Corien; Goetsch, Udo; Monk, Philip; Eckmanns, Tim; Poggensee, Gabriele; Krause, Gérard
2013-01-01
Background Tracing persons who have been in contact with an infectious patient may be very effective in preventing the spread of communicable diseases. However, criteria to decide when to conduct contact tracing are not well established. We have investigated the available evidence for contact tracing with a focus on public ground transport aiming to give guidance in what situations contact tracing should be considered. Methods Relevant infectious diseases suitable for contact tracing in ground transport and a set of disease-specific epidemiological criteria were defined through literature search and structured multistep expert consultations. We developed continuous scales for each criterion to be rated for its relevance to contact tracing in ground transport. We used the Delphi method with an international expert panel to position the values of criteria on the respective scales. Results The study led to the development of the ‘Contact Tracing-Risk Assessment Profile’ (CT-RAP), a decision-making instrument, taking into account pathogen-specific as well as situation-specific criteria. This report describes the methodology of this instrument and presents two examples of ready-to-use CT-RAP for tuberculosis and for meningococcal disease in public ground transport. Discussion The systematic and transparent use of the CT-RAP for tuberculosis and meningococcal disease is likely to facilitate reasonable, efficient and user-friendly decisions with respect to contact tracing. New CT-RAPs for additional pathogens and different settings such as schools and kindergartens are being planned. PMID:24157815
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-28
...Following receipt of a request from the United States Senate Committee on Finance (Committee) dated April 19, 2010, the U.S. International Trade Commission (Commission) instituted investigation No. 332-519, China: Effects of Intellectual Property Infringement and Indigenous Innovation Policies on the U.S. Economy, for the purpose of preparing the second of two reports requested by the Committee, and has scheduled a public hearing in connection with investigations relating to both reports for June 15-16, 2010.
NASA Technical Reports Server (NTRS)
Kelly, Michael J.
2013-01-01
The Alternative Fuel Effects on Contrails & Cruise Emissions (ACCESS) Project Integration Manager requested in July 2012 that the NASA Engineering and Safety Center (NESC) form a team to independently assess aircraft structural failure hazards associated with the ACCESS experiment and to identify potential flight test hazard mitigations to ensure flight safety. The ACCESS Project Integration Manager subsequently requested that the assessment scope be focused predominantly on structural failure risks to the aircraft empennage raft empennage.
Roodbeen, Ruud T J; Schelleman-Offermans, Karen; Lemmens, Paul H H M
2016-06-01
Age limits are effective in reducing alcohol- and tobacco-related harm, however, their effectiveness depends on the extent to which they are complied with. This study aimed to investigate the effectiveness of different age verification systems (AVSs) implemented by 400 Dutch supermarkets on requesting a valid age verification (ID) and on sellers' compliance. A mixed method design was used. Compliance was measured by 800 alcohol and tobacco purchase attempts by 17-year-old mystery shoppers. To analyze the effectiveness of AVSs, logistic regression analyses were performed. Insight into facilitating and hindering factors in the purchase process was obtained by 13 interviews with supermarket managers. Only a tendency toward a positive effect of the presence of the keying-on-date-of-birth AVS or ID swiper/checker was found on ID request for both alcohol and tobacco purchase attempts. The use of the keying-on-date-of-birth AVS or ID swiper/checker significantly increased the odds for compliance after an ID was requested, for both alcohol and tobacco purchase attempts. Managers indicated that ID requests and compliance could be facilitated by providing cashiers with sufficient managerial support, technical support, and regular training about the purchase process and use of the AVS. The usage of AVSs calculating and confirming whether the customer reached the legal purchase age for cashiers significantly increases the odds for cashiers to comply with age limits of alcohol and tobacco. Future research should gain insight into how usage of effective AVSs can be improved and explore the feasibility of implementation and effectiveness in other outlets. Copyright © 2016 The Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Smith, Erin; McLaughlin, T. F.; Neyman, Jennifer; Rinaldi, Lisa
2013-01-01
This study was designed to examine the effects of tracing and fading prompts to improve the handwriting of two preschoolers both diagnosed as Developmentally Delayed (DD) and one of whom had fine motor goals. The study took place in a self-contained special education public preschool classroom located in the Pacific Northwest. The results showed…
A Synopsis of Technical Issues of Concern for Monitoring Trace Elements in Highway and Urban Runoff
Breault, Robert F.; Granato, Gregory E.
2000-01-01
Trace elements, which are regulated for aquatic life protection, are a primary concern in highway- and urban-runoff studies because stormwater runoff may transport these constituents from the land surface to receiving waters. Many of these trace elements are essential for biological activity and become detrimental only when geologic or anthropogenic sources exceed concentrations beyond ranges typical of the natural environment. The Federal Highway Administration and State Transportation Agencies are concerned about the potential effects of highway runoff on the watershed scale and for the management and protection of watersheds. Transportation agencies need information that is documented as valid, current, and scientifically defensible to support planning and management decisions. There are many technical issues of concern for monitoring trace elements; therefore, trace-element data commonly are considered suspect, and the responsibility to provide data-quality information to support the validity of reported results rests with the data-collection agency. Paved surfaces are fundamentally different physically, hydraulically, and chemically from the natural surfaces typical of most freshwater systems that have been the focus of many traceelement- monitoring studies. Existing scientific conceptions of the behavior of trace elements in the environment are based largely upon research on natural systems, rather than on systems typical of pavement runoff. Additionally, the logistics of stormwater sampling are difficult because of the great uncertainty in the occurrence and magnitude of storm events. Therefore, trace-element monitoring programs may be enhanced if monitoring and sampling programs are automated. Automation would standardize the process and provide a continuous record of the variations in flow and water-quality characteristics. Great care is required to collect and process samples in a manner that will minimize potential contamination or attenuation of trace elements and other sources of bias and variability in the sampling process. Trace elements have both natural and anthropogenic sources that may affect the sampling process, including the sample-collection and handling materials used in many trace-element monitoring studies. Trace elements also react with these materials within the timescales typical for collection, processing and analysis of runoff samples. To study the characteristics and potential effects of trace elements in highway and urban runoff, investigators typically sample one or more operationally defined matrixes including: whole water, dissolved (filtered water), suspended sediment, bottom sediment, biological tissue, and contaminant sources. The sampling and analysis of each of these sample matrixes can provide specific information about the occurrence and distribution of trace elements in runoff and receiving waters. There are, however, technical concerns specific to each matrix that must be understood and addressed through use of proper collection and processing protocols. Valid protocols are designed to minimize inherent problems and to maximize the accuracy, precision, comparability, and representativeness of data collected. Documentation, including information about monitoring protocols, quality assurance and quality control efforts, and ancillary data also is necessary to establish data quality. This documentation is especially important for evaluation of historical traceelement monitoring data, because trace-element monitoring protocols and analysis methods have been constantly changing over the past 30 years.
Training evaluation final report
NASA Technical Reports Server (NTRS)
Sepulveda, Jose A.
1992-01-01
In the area of management training, 'evaluation' refers both to the specific evaluation instrument used to determine whether a training effort was considered effective, and to the procedures followed to evaluate specific training requests. This report recommends to evaluate new training requests in the same way new procurement or new projects are evaluated. This includes examining training requests from the perspective of KSC goals and objectives, and determining expected ROI of proposed training program (does training result in improved productivity, through savings of time, improved outputs, and/or personnel reduction?). To determine whether a specific training course is effective, a statement of what constitutes 'good performance' is required. The user (NOT the Training Branch) must define what is 'required level of performance'. This 'model' will be the basis for the design and development of an objective, performance-based, training evaluation instrument.
Discrete Trial Instruction vs. Mand Training for Teaching Children with Autism to Make Requests
ERIC Educational Resources Information Center
Jennett, Heather K.; Harris, Sandra L.; Delmolino, Lara
2008-01-01
The present study compared the effects of discrete trial instruction (DTI) and mand training on the acquisition of independent requests in 6 children with autism. Two multiple-probe designs across participants were conducted with 3 participants receiving mand training followed by DTI and the other 3 receiving DTI followed by mand training. Eye…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-24
... support the Request. In order to facilitate this automation, DTC will create a function that will provide... automation, DTC will be able to reduce the notification time frame on full call MMIs so that effective April... automation input mechanism. Additionally, at the request of the Options Clearing Corporation (``OCC''), DTC...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-27
... Research on Innovation, Competitiveness and Science) SUMMARY: Under the provisions of section 3507(a)(1)(D... (NIH) has submitted to the Office of Management and Budget (OMB) a request to review and approve the... (Science and Technology for America's Reinvestment: Measuring the EffecTs of Research on Innovation...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-24
... Research on Innovation, Competitiveness and Science) Summary: Under the provisions of section 3507(a)(1)(D... (NIH) has submitted to the Office of Management and Budget (OMB) a request to review and approve the... Technology for America's Reinvestment: Measuring the EffecTs of Research on Innovation, Competitiveness and...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-21
... Sudan and Iran; Comment Request AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Request for... exportation of agricultural commodities, medicine, and medical devices to Sudan and Iran. Pursuant to section... commodities, medicine, and medical devices to Sudan and Iran are set forth in 31 CFR 538.523-526 and 31 CFR...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-03
... Sudan and Iran; Comment Request AGENCY: Office of Foreign Assets Control, Treasury. ACTION: Request for... agricultural commodities, medicine, and medical devices to Sudan and Iran. Pursuant to section 906(c) of the... agricultural commodities, medicine, and medical devices to Sudan and Iran are set forth in 31 CFR 538.523-526...