Electrophysiological and mechanical effects of caffeic acid phenethyl ester, a novel cardioprotective agent with antiarrhythmic activity, in guinea-pig heart.

PubMed

Chang, Gwo-Jyh; Chang, Chi-Jen; Chen, Wei-Jan; Yeh, Yung-Hsin; Lee, Hsiao-Yu

2013-02-28

Caffeic acid phenethyl ester (CAPE) is an active component of propolis that exhibits cardioprotective and antiarrhythmic effects. The detailed mechanisms underlying these effects, however, are not entirely understood. The aim of this study was to elucidate the electromechanical effects of CAPE in guinea-pig cardiac preparations. Intracardiac electrograms, left ventricular (LV) pressure, and the anti-arrhythmic efficacy were determined using isolated hearts. Action potentials of papillary muscles were assessed with microelectrodes, Ca(2+) transients were measured by fluorescence, and ion fluxes were measured by patch-clamp techniques. In a perfused heart model, CAPE prolonged the atrio-ventricular conduction interval, the Wenckebach cycle length, and the refractory periods of the AV node and His-Purkinje system, while shortening the QT interval. CAPE reduced the occurrence of reperfusion-induced ventricular fibrillation and decreased LV pressure in isolated hearts. In papillary muscles, CAPE shortened the action potential duration and reduced both the maximum upstroke velocity and contractile force. In fura-2-loaded single ventricular myocytes, CAPE decreased cell shortening and the Ca(2+) transient amplitude. Patch-clamp experiments revealed that CAPE produced a use-dependent decrease in L-type Ca(2+) current (ICa,L) (IC50=1.1 μM) and Na(+) current (INa) (IC50=0.43 μM), caused a negative-shift of the voltage-dependent inactivation and a delay of recovery from inactivation. CAPE decreased the delayed outward K(+) current (IK) slightly, without affecting the inward rectifier K(+) current (IK1). These results suggest that the preferential inhibition of Ca(2+) inward and Na(+) inward currents by CAPE may induce major electromechanical alterations in guinea-pig cardiac preparations, which may underlie its antiarrhythmic action. Copyright © 2013 Elsevier B.V. All rights reserved.

Protective role of caffeic acid on lambda cyhalothrin-induced changes in sperm characteristics and testicular oxidative damage in rats.

PubMed

Abdallah, Fatma Ben; Fetoui, Hamadi; Zribi, Nassira; Fakhfakh, Feiza; Keskes, Leila

2012-08-01

The synthetic pyrethroids are expected to cause deleterious effects on most of the organs and especially on the male reproductive system. The current study was performed to assess the adverse effect of lambda cyhalothrin (LC) on reproductive organs and fertility in male rats and to evaluate the protective role of caffeic acid phenethyl ester (CAPE) in alleviating the detrimental effect of LC on male fertility. A total of 48 male rats were divided into 4 groups (12 rats each): control group received distilled water ad libitum and 1 ml of vehicle solution given intraperitoneally (i.p.); CAPE-treated group received a single i.p. dose of CAPE (10 μmol kg⁻¹ day⁻¹); LC-treated group received 668 ppm of LC through drinking water; and CAPE + LC-treated group received an i.p. injection of CAPE (10 μmol kg⁻¹ day⁻¹) 12 h before the LC administration. The experiment was conducted for 10 consecutive weeks. LC caused a significant increase in testicular malondialdehyde, catalase, superoxide dismutase, glutathione-S-transferase activities, and sperm abnormalities and a significant reduction in testicular glutathione concentration, sperm count, sperm motility, and a live sperm percentage. Conversely, treatment with CAPE improved the reduction in the sperm characteristics, LC-induced oxidative damage of testes and the testicular histopathological alterations. Results indicate that LC exerts significant harmful effects on the male reproductive system and that CAPE reduced the deleterious effects of LC on male fertility.

FEASIBILITY STUDY OF CLIMATE CHANGE IMPACTS ON NITROGEN IN CAPE COD EMBAYMENTS

EPA Science Inventory

The objective of this study is to explore the feasibility of studying potential effects of climate change on impairments resulting from nitrogen loadings in the salt water embayments of Cape Cod. The report includes a recommended plan for studying these impacts, an estimate of t...

Suppression of skin inflammation in keratinocytes and acute/chronic disease models by caffeic acid phenethyl ester.

PubMed

Lim, Kyung-Min; Bae, SeungJin; Koo, Jung Eun; Kim, Eun-Sun; Bae, Ok-Nam; Lee, Joo Young

2015-04-01

Skin inflammation plays a central role in the pathophysiology and symptoms of diverse chronic skin diseases including atopic dermatitis (AD). In this study, we examined if caffeic acid phenethyl ester (CAPE), a skin-permeable bioactive compound from propolis, was protective against skin inflammation using in vitro cell system and in vivo animal disease models. CAPE suppressed TNF-α-induced NF-κB activation and expression of inflammatory cytokines in human keratinocytes (HaCaT). The potency and efficacy of CAPE were superior to those of a non-phenethyl derivative, caffeic acid. Consistently, topical treatment of CAPE (0.5 %) attenuated 12-O-tetradecanoylphorbol-13-acetate(TPA)-induced skin inflammation on mouse ear as CAPE reduced ear swelling and histologic inflammation scores. CAPE suppressed increased expression of pro-inflammatory molecules such as TNF-α, cyclooxygenase-2 and inducible NO synthase in TPA-stimulated skin. TPA-induced phosphorylation of IκB and ERK was blocked by CAPE suggesting that protective effects of CAPE on skin inflammation is attributed to inhibition of NF-κB activation. Most importantly, in an oxazolone-induced chronic dermatitis model, topical application of CAPE (0.5 and 1 %) was effective in alleviating AD-like symptoms such as increases of trans-epidermal water loss, skin thickening and serum IgE as well as histologic inflammation assessment. Collectively, our results propose CAPE as a promising candidate for a novel topical drug for skin inflammatory diseases.

Cytoprotective Effect of Caffeic Acid Phenethyl Ester (CAPE) and Catechol Ring-Fluorinated CAPE Derivatives Against Menadione-Induced Oxidative Stress in Human Endothelial Cells

DTIC Science & Technology

2006-03-31

chlorogenic acid , and rosmari- nic acid did not display any cytoprotective effect in this assay at 15 lM (data not shown). Within the same pas- sage of HUVEC...Cytoprotective effect of caffeic acid phenethyl ester (CAPE) and catechol ring-fluorinated CAPE derivatives against menadione-induced oxidative...accepted 13 March 2006 Available online 31 March 2006 Abstract—Caffeic acid phenethyl ester (CAPE), a natural polyphenolic compound with many

Caffeic acid phenethyl ester inhibits 3-MC-induced CYP1A1 expression through induction of hypoxia-inducible factor-1α

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Hyung Gyun; Han, Eun Hee; Im, Ji Hye

2015-09-25

Caffeic acid phenethyl ester (CAPE), a natural component of propolis, is reported to have anticarcinogenic properties, although its precise chemopreventive mechanism remains unclear. In this study, we examined the effects of CAPE on 3-methylcholanthrene (3-MC)-induced CYP1A1 expression and activities. CAPE reduced the formation of the benzo[a]pyrene-DNA adduct. Moreover, CAPE inhibited 3-MC-induced CYP1A1 activity, mRNA expression, protein level, and promoter activity. CAPE treatment also decreased 3-MC-inducible xenobiotic-response element (XRE)-linked luciferase, aryl hydrocarbons receptor (AhR) transactivation and nuclear localization. CAPE induced hypoxia inducible factor-1α (HIF-1α) protein level and HIF-1α responsible element (HRE) transcriptional activity. CAPE-mediated HIF-1α reduced 3-MC-inducible CYP1A1 protein expression. Takenmore » together, CAPE decreases 3-MC-mediated CYP1A1 expression, and this inhibitory response is associated with inhibition of AhR and HIF-1α induction. - Highlights: • CAPE reduced the formation of the benzo[a]pyrene-DNA adduct. • CAPE inhibited 3-MC-induced CYP1A1 expression. • CAPE induced HIF-1α induction. • CAPE-mediated HIF-1α reduced 3-MC-inducible CYP1A1 expression.« less

The Effect of Performance Assessment-Driven Instruction on the Attitude and Achievement of Senior High School Students in Mathematics in Cape Coast Metropolis, Ghana

ERIC Educational Resources Information Center

Arhin, Ato Kwamina

2015-01-01

The study was a quasi-experimental research project conducted to investigate the effect of performance assessment-driven instructions on the attitude and achievement in mathematics of senior high school students in Ghana at Ghana National College in Cape Coast. Two Form 1 science classes were used for the study and were assigned as experimental…

Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.

PubMed

Mahmoud, N N; Carothers, A M; Grunberger, D; Bilinski, R T; Churchill, M R; Martucci, C; Newmark, H L; Bertagnolli, M M

2000-05-01

Epidemiological studies consistently indicate that consumption of fruits and vegetables lowers cancer risk in humans and suggest that certain dietary constituents may be effective in preventing colon cancer. Plant-derived phenolic compounds manifest many beneficial effects and can potentially inhibit several stages of carcinogenesis in vivo. In this study, we investigated the efficacy of several plant-derived phenolics, including caffeic acid phenethyl ester (CAPE), curcumin, quercetin and rutin, for the prevention of tumors in C57BL/6J-Min/+ (Min/+) mice. These animals bear a germline mutation in the Apc gene and spontaneously develop numerous intestinal adenomas by 15 weeks of age. At a dietary level of 0.15%, CAPE decreased tumor formation in Min/+ mice by 63%. Curcumin induced a similar tumor inhibition. Quercetin and rutin, however, both failed to alter tumor formation at dietary levels of 2%. Examination of intestinal tissue from the treated animals showed that tumor prevention by CAPE and curcumin was associated with increased enterocyte apoptosis and proliferation. CAPE and curcumin also decreased expression of the oncoprotein beta-catenin in the enterocytes of the Min/+ mouse, an observation previously associated with an antitumor effect. These data place the plant phenolics CAPE and curcumin among a growing list of anti-inflammatory agents that suppress Apc-associated intestinal carcinogenesis.

Effect of caffeic acid phenethyl ester on the regression of endometrial explants in an experimental rat model.

PubMed

Güney, Mehmet; Nasir, Serdar; Oral, Baha; Karahan, Nermin; Mungan, Tamer

2007-04-01

The objective of this study is to determine the effects of antioxidant and anti-inflammatory caffeic acid phenethyl ester (CAPE) on experimental endometriosis, peritoneal superoxide dismutase (SOD) and catalase (CAT) activities, and malondialdehyde (MDA) levels in the rat endometriosis model. Thirty rats with experimentally induced endometriosis were randomly divided into 2 groups and treated for 4 weeks with intraperitoneal CAPE (CAPE-treated group; 10 micromol/kg/d, n = 13) or vehicle (control group; n = 13). The volume and weight changes of the implants were calculated. Immunohistochemical and histologic examinations of endometriotic explants by semiquantitative analysis and measurements of peritoneal SOD, CAT, and MDA levels were made. Following 4 weeks of treatment with CAPE, there were significant differences in posttreatment spherical volumes (37.4 +/- 14.7 mm(3) vs 147.5 +/- 41.2 mm(3)) and explant weights (49.1 +/- 28.5 mg vs 158.9 +/- 50.3 mg) between the CAPE-treated groups and controls. The mean evaluation nomogram levels in glandular epithelium for COX-2 positivity by scoring system were 2.1 +/- 0.3 in the CAPE-treated group and 3.9 +/- 0.3 in the control group. In the CAPE-treated group, peritoneal levels of MDA and activities of SOD and CAT significantly decreased when compared with the control group (P < .01). Histologic analysis of the explants demonstrated mostly atrophy and regression in the treatment group, and semiquantitative analysis showed significantly lower scores in rats treated with CAPE compared with the control group. CAPE appeared to cause regression of experimental endometriosis.

Toward better assessment of tornado potential in typhoons: Significance of considering entrainment effects for CAPE

NASA Astrophysics Data System (ADS)

Sueki, Kenta; Niino, Hiroshi

2016-12-01

The characteristics of typhoons that spawned tornadoes (tornadic typhoons: TTs) in Japan from 1991 to 2013 were investigated by composite analysis using the Japanese 55 year Reanalysis and compared with those of typhoons that did not spawn tornadoes (nontornadic typhoons: NTs). We found that convective available potential energy (CAPE), which considers the effects of entrainment (entraining CAPE: E-CAPE), and storm-relative environmental helicity (SREH) are significantly large in the northeast quadrant of TTs where tornadoes frequently occur and that E-CAPE and SREH in that quadrant for TTs are larger than those for NTs. On the other hand, ordinary CAPE without entrainment does not account for the spatial distribution of tornado occurrences nor does it distinguish TTs from NTs. E-CAPE is sensitive to humidity in the midtroposphere; thus, it is effective for detecting a conditionally unstable layer up to about 550 hPa, which is distinctive of TTs.

Mutuality at the center: health promotion with Cape Verdean immigrant women.

PubMed

De Jesus, Maria

2009-02-01

Public health care researchers, policy makers, and providers are increasingly interested in developing more effective and culturally responsive health promotion theories and interventions for diverse immigrant populations. The purpose of this study was to develop health promotion theory that validates the local knowledge and experiences of Cape Verdean women health promoters who work with immigrant women in their community. In-depth, semi-structured interviews were conducted with nine culturally savvy, community-based Cape Verdean women health promoters about their perspectives and daily experiences of health promotion practice with Cape Verdean immigrant women. This study used Glaserian grounded theory to analyze the interviews. This approach identified concepts and developed an integrated process through which to theorize about the practice of health promoters. For Cape Verdean women health promoters, a process of creating relationships was a key to promoting women's health. The relational theory of health promotion practice reflects these dynamic processes, properties, and stages through which Cape Verdean women health promoters develop mutually engaging relationships with immigrant women. CONCLUSION. These findings challenge health care professionals to broaden the repertoire of health promotion strategies to include relationship-building between health promoters and community women. Through these relationships health promoters can understand the complex structural, cultural, and community factors that influence immigrant women's health and incorporate that knowledge into more effective health promotion practices.

Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells.

PubMed

Izuta, Hiroshi; Shimazawa, Masamitsu; Tsuruma, Kazuhiro; Araki, Yoko; Mishima, Satoshi; Hara, Hideaki

2009-11-17

Vascular endothelial growth factor (VEGF) is a key regulator of pathogenic angiogenesis in diseases such as cancer and diabetic retinopathy. Bee products [royal jelly (RJ), bee pollen, and Chinese red propolis] from the honeybee, Apis mellifera, have been used as traditional health foods for centuries. The aim of this study was to investigate the anti-angiogenic effects of bee products using human umbilical vein endothelial cells (HUVECs). In an in vitro tube formation assay, HUVECs and fibroblast cells were incubated for 14 days with VEGF and various concentrations of bee products [RJ, ethanol extract of bee pollen, ethanol extract of Chinese red propolis and its constituent, caffeic acid phenethyl ester (CAPE)]. To clarify the mechanism of in vitro angiogenesis, HUVEC proliferation and migration were induced by VEGF with or without various concentrations of RJ, bee pollen, Chinese red propolis, and CAPE. RJ, bee pollen, Chinese red propolis, and CAPE significantly suppressed VEGF-induced in vitro tube formation in the descending order: CAPE > Chinese red propolis > bee pollen > RJ. RJ and Chinese red propolis suppressed both VEGF-induced HUVEC proliferation and migration. In contrast, bee pollen and CAPE suppressed only the proliferation. Among the bee products, Chinese red propolis and CAPE in particular showed strong suppressive effects against VEGF-induced angiogenesis. These findings indicate that Chinese red propolis and CAPE may have potential as preventive and therapeutic agents against angiogenesis-related human diseases.

Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers affecting NF-κB and NOS2 and NRF2 expression.

PubMed

Romana-Souza, Bruna; Dos Santos, Jeanine Salles; Monte-Alto-Costa, Andréa

2018-06-01

In pressure ulcers, the synthesis of reactive oxygen species induced by ischemia and reperfusion leads to chronic inflammation and tissue damage, which impair the closure of these lesions. Caffeic acid phenethyl ester (CAPE), found in propolis, promotes cutaneous wound healing of acute lesions and severe burns. However, the effects of CAPE on wound healing of pressure ulcers have not been investigated. This study investigated the effects of CAPE administration in a murine model of pressure ulcers. To induce pressure ulcers, two cycles of ischemia and reperfusion by external application of two magnetic plates were performed in the skin dorsum of mice. After the last cycle, animals were treated daily with CAPE or vehicle until they were euthanized. The nitric oxide synthesis, lipid peroxidation, macrophage migration, protein nuclear factor kappa B and nitric-oxide synthase-2 expression were increased 3 days after ulceration but decreased 7 days later, in pressure ulcers of the CAPE group compared to that of the control group. CAPE reduced the protein expression of nuclear factor-erythroid2-related factor 2 in pressure ulcers 3 days after ulceration, but increased 7 days later. Myofibroblast density was increased in the CAPE group 7 days after ulceration, but reduced 12 days later when compared to control group. In addition, CAPE promoted collagen deposition, re-epithelialization and wound closure of mice pressure ulcers 12 days after ulceration. CAPE brings forward inflammatory response and oxidative damage involved in injury by ischemia and reperfusion, promoting dermal reconstruction and closure of pressure ulcers. Copyright © 2017. Published by Elsevier Inc.

Homework Policy Review: A Case Study of A Public School in the Western Cape Province

ERIC Educational Resources Information Center

Pfeiffer, Verbra

2018-01-01

A key concern today is the question of homework in our nation's public schools. In this study, an investigation was conducted with the first no-homework policy, which has been introduced in one of the primary schools in the Western Cape. This study seeks to determine whether a no-homework policy will validate a positive or negative effect on…

Effects of caffeic acid phenethyl ester on palatal mucosal defects and tooth extraction sockets

PubMed Central

Günay, Ahmet; Arpağ, Osman Fatih; Atilgan, Serhat; Yaman, Ferhan; Atalay, Yusuf; Acikan, İzzet

2014-01-01

Aim The purpose of this study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) on palatal mucosal defects and tooth extraction sockets in an experimental model. Materials and methods Forty-two male Sprague-Dawley rats with a mean age of 7 weeks and weighing 280–490 g were used in this study. The rats were randomly divided into two groups: group A (the control group, n=21) and group B (the experimental group, n=21). Under anesthesia with ketamine (8 mg/100 g, intraperitoneally), palatal mucosal defects were created and tooth extraction was performed in the rats in groups A and B. Group A received no treatment, whereas group B received CAPE. CAPE was injected daily (10 μmol/kg, intraperitoneally). The rats were killed on days 7, 14, and 30 after the procedures. Palatal mucosa healing and changes in bone tissue and fibrous tissue were evaluated histopathologically. Result Pairwise comparisons showed no statistically significant difference between days 7 and 14 in either group (P>0.05). At day 30, bone healing was significantly better in group B (CAPE) than in group A (control) (P<0.05). Fibrinogen levels at day 30 were significantly higher in group A (control) than in group B (CAPE) (P<0.05). Pairwise comparisons showed no statistically significant difference in palatal mucosa healing levels between days 7 and 14 in both groups (P>0.05). Conclusion In conclusion, the findings of this study suggest that CAPE can significantly improve tooth socket healing. PMID:25364232

Caffeic acid phenethyl ester guards against benign prostate hypertrophy in rats: Role of IGF-1R/protein kinase-B (Akt)/β-catenin signaling.

PubMed

Omar, Hany A; Tolba, Mai F

2018-06-01

Benign prostate hypertrophy (BPH) is among the most common diseases with a huge impact on the quality of life of elderly men. There is a current need for the development of well-tolerated and effective preventive strategies to improve the clinical outcome. Caffeic acid phenethyl ester (CAPE) is an important active ingredient isolated from honey-bee propolis with potent anti-proliferative, anti-inflammatory and antioxidant effects. These properties promote CAPE as a promising candidate to be tested as an alternative therapy for BPH, which is still uninvestigated. Herein, we tested the ability of CAPE to guard against testosterone-induced BPH and investigated the involvement of IGF1-R/Akt/β-catenin signaling as a protective mechanism in testosterone-induced BPH rat model. Treatment with CAPE reduced testosterone-induced increase in the prostate index and histopathological alterations. In addition, co-treatment with CAPE significantly suppressed insulin-like growth factor-1 receptor (IGF-1R)/Akt/β-catenin/cyclinD1 axis as well as tumor necrosis factor-α level and nuclear factor (NF)-kB activity. Furthermore, the treatment with CAPE replenished the antioxidant defense systems, superoxide dismutase (SOD) and reduced glutathione (GSH) with subsequent reduction in prostate tissue lipid peroxides. This study highlights the potential merit of CAPE-enriched propolis formulations to protect elderly men against the development of BPH. © 2018 IUBMB Life, 70(6):519-528, 2018. © 2018 International Union of Biochemistry and Molecular Biology.

Effect of caffeic acid phenethyl ester on oxidant and anti-oxidant status of liver and serum in a rat model with acute methanol intoxication.

PubMed

Yazgan, Ü C; Elbey, B; Kuş, S; Baykal, B; Keskin, I; Yılmaz, A; Şahin, A

2017-05-01

Methanol toxicity is one of the major public health problems because it can cause severe morbidity and mortality. Methanol intoxication causes changes in the balance between the production of free radicals and antioxidant capacity. We aimed to investigate the effects of caffeic acid phenethyl ester (CAPE) on the total oxidant status, total antioxidant status (TAS), and oxidative stress index (OSI) parameters of the liver and the serum in a rat model of acute methanol intoxication. Rats were treated with intraperitoneal (i.p.) Methotrexate (MTX) for 7 days. On the 8th day, i.p. Methanol was administered in the methanol, ethanol and CAPE groups. Four hours after methanol treatment, ethanol was injected i.p. in the ethanol group; CAPE (i.p.) in the CAPE group; serum physiologic i.p. in other groups. After 8 hours, rats were killed and the serum and the liver samples were obtained for biochemical analyses. The OSI value was significantly higher in the methanol group compared to the ethanol and CAPE groups. Serum TAS levels of the methanol group were significantly different compared to the control group, but not compared to the MTX group. The amelioration of oxidative stress was greater in the CAPE group compared to the ethanol group but was not statistically significant. This study demonstrates that CAPE treatment ameliorates oxidative stress in the serum and liver in a rat model of acute methanol intoxication.

Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells

PubMed Central

2009-01-01

Background Vascular endothelial growth factor (VEGF) is a key regulator of pathogenic angiogenesis in diseases such as cancer and diabetic retinopathy. Bee products [royal jelly (RJ), bee pollen, and Chinese red propolis] from the honeybee, Apis mellifera, have been used as traditional health foods for centuries. The aim of this study was to investigate the anti-angiogenic effects of bee products using human umbilical vein endothelial cells (HUVECs). Methods In an in vitro tube formation assay, HUVECs and fibroblast cells were incubated for 14 days with VEGF and various concentrations of bee products [RJ, ethanol extract of bee pollen, ethanol extract of Chinese red propolis and its constituent, caffeic acid phenethyl ester (CAPE)]. To clarify the mechanism of in vitro angiogenesis, HUVEC proliferation and migration were induced by VEGF with or without various concentrations of RJ, bee pollen, Chinese red propolis, and CAPE. Results RJ, bee pollen, Chinese red propolis, and CAPE significantly suppressed VEGF-induced in vitro tube formation in the descending order: CAPE > Chinese red propolis >> bee pollen > RJ. RJ and Chinese red propolis suppressed both VEGF-induced HUVEC proliferation and migration. In contrast, bee pollen and CAPE suppressed only the proliferation. Conclusion Among the bee products, Chinese red propolis and CAPE in particular showed strong suppressive effects against VEGF-induced angiogenesis. These findings indicate that Chinese red propolis and CAPE may have potential as preventive and therapeutic agents against angiogenesis-related human diseases. PMID:19917137

The Effects of Community Violence on Children in Cape Town, South Africa

ERIC Educational Resources Information Center

Shields, Nancy; Nadasen, Kathy; Pierce, Lois

2008-01-01

Objective: The primary objective of the study was to investigate the relationship between exposure to community violence (neighborhood, school, police, and gang violence) and psychological distress in a sample of children living in the Cape Town, South Africa area. Another objective was to identify variables that moderate and mediate the…

Pilot study of a culturally adapted psychoeducation (CaPE) intervention for bipolar disorder in Pakistan.

PubMed

Husain, Muhammad Ishrat; Chaudhry, Imran B; Rahman, Raza R; Hamirani, Munir M; Mehmood, Nasir; Haddad, Peter M; Hodsoll, John; Young, Allan H; Naeem, Farooq; Husain, Nusrat

2017-12-01

Despite the use of maintenance medication, recurrence rates in bipolar affective disorder (BPAD) are high. To date, there are no clinical trials that have investigated the use of psychological interventions in bipolar disorder in Pakistan. The purpose of the study was to assess the feasibility and acceptability of a culturally adapted bipolar psychoeducation programme (CaPE) in Pakistan. Thirty-four euthymic bipolar I and II outpatients were randomized to either 12 weekly sessions of individual psychoeducation plus Treatment As Usual (Intervention) or Treatment As Usual (TAU) (Control). Outcomes were assessed using the Young Mania Rating Scale (YMRS), Beck Depression Inventory (BDI), EuroQoL (EQ-5D), Bipolar Knowledge and Attitudes and Questionnaire (BKAQ), and a self-reported measure of medication adherence (Morisky Medication Adherence Scale-4 items, MMAS-4). Effect sizes were derived from baseline adjusted standardized regression coefficients. Retention in the study was good, 80% of patients in the TAU follow-up assessment and 100% of patients in the CaPE group attended all 12 sessions. Patient satisfaction was higher in the CaPE group relative to control (ES = 1.41). Further, there were large effect sizes shown for CaPE versus TAU for medication adherence (MMAS-4: ES = 0.81), knowledge and attitudes towards bipolar (BKAQ: ES = 0.68), mania (YMRS: ES = 1.18), depression (BDI: ES = 1.17) and quality of life measures (EQ-5D: ES ⇒ 0.88). Culturally adapted psychoeducation intervention is acceptable and feasible, and can be effective in improving mood symptoms and knowledge and attitudes to BPAD when compared with TAU. Larger scale studies are needed to confirm our findings. Clinicaltrials.gov identifier NCT02210390.

Caffeic Acid Phenethyl Ester Regulates PPAR's Levels in Stem Cells-Derived Adipocytes

PubMed Central

Vanella, Luca; Tibullo, Daniele; Godos, Justyna; Pluchinotta, Francesca Romana; Di Giacomo, Claudia; Sorrenti, Valeria; Acquaviva, Rosaria; Russo, Alessandra; Li Volti, Giovanni; Barbagallo, Ignazio

2016-01-01

Hypertrophic obesity inhibits activation of peroxisome proliferators-activated receptor gamma (PPARγ), considered the key mediator of the fully differentiated and insulin sensitive adipocyte phenotype. We examined the effects of Caffeic Acid Phenethyl Ester (Cape), isolated from propolis, a honeybee hive product, on Adipose Stem Cells (ASCs) differentiation to the adipocyte lineage. Finally we tested the effects of Cape on insulin-resistant adipocytes. Quantification of Oil Red O-stained cells showed that lipid droplets decreased following Cape treatment as well as radical oxygen species formation. Additionally, exposure of ASC to high glucose levels decreased adiponectin and increased proinflammatory cytokines mRNA levels, which were reversed by Cape-mediated increase of insulin sensitivity. Cape treatment resulted in decreased triglycerides synthesis and increased beta-oxidation. Exposure of ASCs to Lipopolysaccharide (LPS) induced a reduction of PPARγ, an increase of IL-6 levels associated with a well-known stimulation of lipolysis; Cape partially attenuated the LPS-mediated effects. These observations reveal the main role of PPARγ in the adipocyte function and during ASC differentiation. As there is now substantial interest in functional food and nutraceutical products, the observed therapeutic value of Cape in insulin-resistance related diseases should be taken into consideration. PMID:26904104

Groundwater resources of Mosteiros basin, island of Fogo, Cape Verde, West Africa

USGS Publications Warehouse

Heilweil, Victor M.; Gingerich, Stephen B.; Plummer, Niel; Verstraeten, Ingrid M.

2010-01-01

Groundwater resources in Cape Verde provide water for agriculture, industry, and human consumption. These resources are limited and susceptible to contamination. Additional groundwater resources are needed for continued agricultural development, particularly during times of drought, but increased use and (or) climatic change may have adverse effects on the quantity and quality of freshwater available. In volcanic island aquifers such as those of Cape Verde, a lens of fresh groundwater typically ?floats? upon a layer of brackish water at the freshwater/saltwater boundary, and increased pumping may cause salt water intrusion or other contamination. A recent U.S. Geological Survey study assessed baseline groundwater conditions in watersheds on three islands of Cape Verde to provide the scientific basis for sustainably developing water resources and minimizing future groundwater depletion and contamination.

Effect of ethylene and 1-methylcyclopropene on the postharvest behavior of cape gooseberry fruits (Physalis peruviana L.).

PubMed

Balaguera-López, Helber E; Espinal-Ruiz, Mauricio; Zacarías, Lorenzo; Herrera, Aníbal O

2017-01-01

Cape gooseberry (Physalis peruviana L.) fruits are highly perishable berries that exhibit a climacteric respiratory behavior. The objective of this study was to evaluate the effect of ethylene and the ethylene action inhibitor 1-methylcyclopropene on the postharvest behavior of cape gooseberry fruits (ecotype Colombia). Fruits were treated with ethylene, in an ethephon application (1000 µL L -1 ), and pretreated with 1-methylcyclopropene (1 µL L -1 ), 1-methylcyclopropene+ethylene, and results compared with a control without application. Subsequently, the fruits were maintained at room temperature (20 ℃, 75% RH) for up to 11 days. The pretreatment of the cape gooseberry fruits with 1-methylcyclopropene delayed most of the ripening-associated parameters, with a reduction in the respiration rate and ethylene production, skin color development, total soluble solids, total carotenoid content, loss of firmness, loss of total titratable acidity and emission of volatile compounds such as ethyl octanoate, ethyl butanoate, ethyl decanoate, and hexyl decanoate. Conversely, application of ethephon accelerated most of these physiological changes and also overcame most of the effects prevented by the ethylene action inhibitor. Altogether, the results supported the idea of a climacteric-like behavior for cape gooseberry fruits and pointing out that the pretreatment with 1-methylcyclopropene may be a promising and efficient postharvest treatment to delay maturity and extend the postharvest period. © The Author(s) 2016.

Migration Rate Inhibition of Breast Cancer Cells Treated by Caffeic Acid and Caffeic Acid Phenethyl Ester: An In Vitro Comparison Study.

PubMed

Kabała-Dzik, Agata; Rzepecka-Stojko, Anna; Kubina, Robert; Jastrzębska-Stojko, Żaneta; Stojko, Rafał; Wojtyczka, Robert Dariusz; Stojko, Jerzy

2017-10-19

One of the deadliest cancers among women is a breast cancer. Research has shown that two natural substances occurring in propolis, caffeic acid (CA) and caffeic acid phenethyl ester (CAPE), have significant anticancer effects. The purpose of our in vitro study was to compare cytotoxic activity and migration rate inhibition using CA and CAPE (doses of 50 and 100 µm) against triple-negative, MDA-MB-231 breast adenocarcinoma line cells, drawn from Caucasian women. Viability was measured by XTT-NR-SRB assay (Tetrazolium hydroxide-Neutral Red-Sulforhodamine B) for 24 h and 48 h periods. Cell migration for wound healing assay was taken for 0 h, 8 h, 16 h, and 24 h periods. CAPE displayed more than two times higher cytotoxicity against MDA-MB-231 cells. IC 50 values for the XTT assay were as follows: CA for 24 h and 48 h were 150.94 µM and 108.42 µM, respectively, while CAPE was 68.82 µM for 24 h and 55.79 µM for 48 h. For the NR assay: CA was 135.85 µM at 24 h and 103.23 µM at 48 h, while CAPE was 64.04 µM at 24 h and 53.25 µM at 48 h. For the SRB assay: CA at 24 h was 139.80 µM and at 48 h 103.98 µM, while CAPE was 66.86 µM at 24 h and 47.73 µM at 48 h. Both agents suspended the migration rate; however, CAPE displayed better activity. Notably, for the 100 µM CAPE dose, motility of the tested breast carcinoma cells was halted.

Caffeic acid phenethyl ester attenuates pathological cardiac hypertrophy by regulation of MEK/ERK signaling pathway in vivo and vitro.

PubMed

Ren, Jie; Zhang, Nan; Liao, Haihan; Chen, Si; Xu, Ling; Li, Jing; Yang, Zheng; Deng, Wei; Tang, Qizhu

2017-07-15

To explore the effects of caffeic acid phenethyl ester (CAPE) on cardiac hypertrophy induced by pressure overload. Male wild-type C57 mice, aged 8-10weeks, were used for aortic banding (AB) to induce cardiac hypertrophy. CAPE or (resveratrol) RS was administered from the 3rd day after AB surgery for 6weeks. Echocardiography and hemodynamic analysis were performed to estimate cardiac function. Mice hearts were collected for H&E and PSR staining. Western blot analysis and quantitative PCR were performed for to investigate molecular mechanism. We further confirmed our findings in H9c2 cardiac fibroblasts treated with PE or CAPE. CAPE protected against cardiac hypertrophy induced by pressure overload, as evidenced by inhibition of cardiac hypertrophy and improvement in mouse cardiac function. The effect of CAPE on cardiac hypertrophy was mediated via inhibition of the MEK/ERK and TGFβ-Smad signaling pathways. We also demonstrated that CAPE protected H9c2 cells from PE-induced hypertrophy in vitro via a similar molecular mechanism as seen in the mouse heart. Finally, CAPE seemed to be as effective as RS for treatment of pressure overload induced mouse cardiac hypertrophy. Our results suggest that CAPE may play an important role in the regulation of cardiac hypertrophy induced by pressure overload via negative regulation of the MEK/ERK and TGFβ/Smad signaling pathways. These results indicate that CAPE could potentially be used for treatment of cardiac hypertrophy. Copyright © 2017 Elsevier Inc. All rights reserved.

Groundwater resources of Ribeira Paúl basin, island of Santo Antão, Cape Verde, West Africa

USGS Publications Warehouse

Heilweil, Victor M.; Gingerich, Stephen B.; Verstraeten, Ingrid M.

2010-01-01

Groundwater resources in Cape Verde provide water for agriculture, industry, and human consumption. These resources are limited and susceptible to contamination. Additional groundwater resources are needed for continued agricultural development, particularly during times of drought, but increased use and (or) climatic change may have adverse effects on the quantity and quality of freshwater available. In volcanic island aquifers such as those of Cape Verde, a lens of fresh groundwater typically ?floats? upon a layer of brackish water at the freshwater/saltwater boundary, and increased pumping may cause salt water intrusion or other contamination. A recent U.S. Geological Survey study assessed baseline groundwater conditions in watersheds on three islands of Cape Verde to provide the scientific basis for sustainably developing water resources and minimizing future groundwater depletion and contamination.

Groundwater resources of Ribeira Fajã basin, island of São Nicolau, Cape Verde, West Africa

USGS Publications Warehouse

Heilweil, Victor M.; Gingerich, Stephen B.; Plummer, Niel; Verstraeten, Ingrid M.

2010-01-01

Groundwater resources in Cape Verde provide water for agriculture, industry, and human consumption. These resources are limited and susceptible to contamination. Additional groundwater resources are needed for continued agricultural development, particularly during times of drought, but increased use and (or) climatic change may have adverse effects on the quantity and quality of freshwater available. In volcanic island aquifers such as those of Cape Verde, a lens of fresh groundwater typically ?floats? upon a layer of brackish water at the freshwater/saltwater boundary, and increased pumping may cause salt water intrusion or other contamination. A recent U.S. Geological Survey study assessed baseline groundwater conditions in watersheds on three islands of Cape Verde to provide the scientific basis for sustainably developing water resources and minimizing future groundwater depletion and contamination.

Cytoprotection of human endothelial cells against oxidative stress by 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Im): application of systems biology to understand the mechanism of action.

PubMed

Wang, Xinyu; Bynum, James A; Stavchansky, Solomon; Bowman, Phillip D

2014-07-05

Cellular damage from oxidative stress, in particular following ischemic injury, occurs during heart attack, stroke, or traumatic injury, and is potentially reducible with appropriate drug treatment. We previously reported that caffeic acid phenethyl ester (CAPE), a plant-derived polyphenolic compound, protected human umbilical vein endothelial cells (HUVEC) from menadione-induced oxidative stress and that this cytoprotective effect was correlated with the capacity to induce heme oxygenase-1 (HMOX1) and its protein product, a phase II cytoprotective enzyme. To further improve this cytoprotective effect, we studied a synthetic triterpenoid, 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole (CDDO-Im), which is known as a potent phase II enzyme inducer with antitumor and anti-inflammatory activities, and compared it to CAPE. CDDO-Im at 200nM provided more protection to HUVEC against oxidative stress than 20μM CAPE. We explored the mechanism of CDDO-Im cytoprotection with gene expression profiling and pathway analysis and compared to that of CAPE. In addition to potent up-regulation of HMOX1, heat shock proteins (HSP) were also found to be highly induced by CDDO-Im in HUVEC. Pathway analysis results showed that transcription factor Nrf2-mediated oxidative stress response was among the top canonical pathways commonly activated by both CDDO-Im and CAPE. Compared to CAPE, CDDO-Im up-regulated more HSP and some of them to a much higher extent. In addition, CDDO-Im treatment affected Nrf2 pathway more significantly. These findings may provide an explanation why CDDO-Im is a more potent cytoprotectant than CAPE against oxidative stress in HUVEC. Copyright © 2014 Elsevier B.V. All rights reserved.

Hydrophilicity and antifouling property of membrane materials from cellulose acetate/polyethersulfone in DMAc.

PubMed

Sun, Zhonghua; Chen, Fushan

2016-10-01

In this study, cellulose acetate (CA) was blended with polyethersulfone (PES) to endow the ultrafiltration membrane with the improved hydrophilicity and antifouling property by using N,N-dimethylacetamide (DMAc) as the solvent. The effects of blend composition and evaporation time on the mechanical strength and pure water flux were investigated. It was found that the optimal composition of the casting solution was: 18wt% (PES), 4wt% (Polyvinylpyrrolidone K30), 3wt% (CA) and 20s (Evaporation time). The characteristics of CA-PES blend membranes were investigated through the methods of contact angle goniometer, antifouling property, compatibility, thermo gravimetric analysis and SEM. The results showed that the hydrophilicity and antifouling property of CA-PES ultrafiltration membranes were enhanced in comparison with the pure PES membranes. The CA-PES membranes exhibited semi-compatibility and good thermal stability below 270°C. This study provided a potential industrial application prospect of CA-PES membranes prepared in DMAc. Copyright © 2016 Elsevier B.V. All rights reserved.

Does Assessment Type Matter? A Measurement Invariance Analysis of Online and Paper and Pencil Assessment of the Community Assessment of Psychic Experiences (CAPE)

PubMed Central

Vleeschouwer, Marloes; Schubart, Chris D.; Henquet, Cecile; Myin-Germeys, Inez; van Gastel, Willemijn A.; Hillegers, Manon H. J.; van Os, Jim J.; Boks, Marco P. M.; Derks, Eske M.

2014-01-01

Background The psychometric properties of an online test are not necessarily identical to its paper and pencil original. The aim of this study is to test whether the factor structure of the Community Assessment of Psychic Experiences (CAPE) is measurement invariant with respect to online vs. paper and pencil assessment. Method The factor structure of CAPE items assessed by paper and pencil (N = 796) was compared with the factor structure of CAPE items assessed by the Internet (N = 21,590) using formal tests for Measurement Invariance (MI). The effect size was calculated by estimating the Signed Item Difference in the Sample (SIDS) index and the Signed Test Difference in the Sample (STDS) for a hypothetical subject who scores 2 standard deviations above average on the latent dimensions. Results The more restricted Metric Invariance model showed a significantly worse fit compared to the less restricted Configural Invariance model (χ2(23) = 152.75, p<0.001). However, the SIDS indices appear to be small, with an average of −0.11. A STDS of −4.80 indicates that Internet sample members who score 2 standard deviations above average would be expected to score 4.80 points lower on the CAPE total scale (ranging from 42 to 114 points) than would members of the Paper sample with the same latent trait score. Conclusions Our findings did not support measurement invariance with respect to assessment method. Because of the small effect sizes, the measurement differences between the online assessed CAPE and its paper and pencil original can be neglected without major consequences for research purposes. However, a person with a high vulnerability for psychotic symptoms would score 4.80 points lower on the total scale if the CAPE is assessed online compared to paper and pencil assessment. Therefore, for clinical purposes, one should be cautious with online assessment of the CAPE. PMID:24465389

Association analysis for disease resistance to Fusarium oxysporum in cape gooseberry (Physalis peruviana L).

PubMed

Osorio-Guarín, Jaime A; Enciso-Rodríguez, Felix E; González, Carolina; Fernández-Pozo, Noé; Mueller, Lukas A; Barrero, Luz Stella

2016-03-18

Vascular wilt caused by Fusarium oxysporum is the most important disease in cape gooseberry (Physalis peruviana L.) in Colombia. The development of resistant cultivars is considered one of the most cost-effective means to reduce the impact of this disease. In order to do so, it is necessary to provide breeders with molecular markers and promising germplasm for introgression of different resistance loci as part of breeding schemes. Here we described an association mapping study in cape gooseberry with the goal to: (i) select promising materials for use in plant breeding and (ii) identify SNPs associated with the cape gooseberry resistance response to the F. oxysporum pathogen under greenhouse conditions, as potential markers for cape gooseberry breeding. We found a total of 21 accessions with different resistance responses within a diversity panel of 100 cape gooseberry accessions. A total of 60,663 SNPs were also identified within the same panel by means of GBS (Genotyping By Sequencing). Model-based population structure and neighbor-joining analyses showed three populations comprising the cape gooseberry panel. After correction for population structure and kinship, we identified SNPs markers associated with the resistance response against F. oxysporum. The identification of markers was based on common tags using the reference genomes of tomato and potato as well as the root/stem transcriptome of cape gooseberry. By comparing their location with the tomato genome, 16 SNPs were found in genes involved in defense/resistance response to pathogens, likewise when compared with the genome of potato, 12 markers were related. The work presented herein provides the first association mapping study in cape gooseberry showing both the identification of promising accessions with resistance response phenotypes and the identification of a set of SNP markers mapped to defense/resistance response genes of reference genomes. Thus, the work also provides new knowledge on candidate genes involved in the P. peruviana - F. oxysporum pathosystem as a foundation for further validation in marker-assisted selection. The results have important implications for conservation and breeding strategies in cape gooseberry.

Direct interaction between caffeic acid phenethyl ester and human neutrophil elastase inhibits the growth and migration of PANC-1 cells.

PubMed

Duan, Jianhui; Xiaokaiti, Yilixiati; Fan, Shengjun; Pan, Yan; Li, Xin; Li, Xuejun

2017-05-01

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant tumors of the digestive system, but the mechanisms of its development and progression are unclear. Inflammation is thought to be fundamental to pancreatic cancer development and caffeic acid phenethyl ester (CAPE) is an active component of honey bee resin or propolis with anti-inflammatory and anticancer activities. We investigated the inhibitory effects of CAPE on cell growth and migration induced by human neutrophil elastase (HNE) and report that HNE induced cancer cell migration at low doses and growth at higher doses. In contrast, lower CAPE doses inhibited migration and higher doses of CAPE inhibited the growth induced by HNE. HNE activity was significantly inhibited by CAPE (7.5-120 µM). Using quantitative real-time PCR and western blotting, we observed that CAPE (18-60 µM) did not affect transcription and translation of α1-antitrypsin (α1-AT), an endogenous HNE inhibitor. However, in an in silico drug target docking model, we found that CAPE directly bound to the binding pocket of HNE (25.66 kcal/mol) according to CDOCKER, and the residue of the catalytic site stabilized the interaction between CAPE and HNE as evidenced by molecular dynamic simulation. Response unit (RU) values of surface plasmon resonance (SPR) significantly increased with incremental CAPE doses (7.5-120 µM), indicating that CAPE could directly bind to HNE in a concentration-dependent manner. Thus, CAPE is an effective inhibitor of HNE via direct interaction whereby it inhibits the migration and growth of PANC-1 cells in a dose-dependent manner.

Individual- and Neighbourhood-Level Indicators of Subjective Well-Being in a Small and Poor Eastern Cape Township: The Effect of Health, Social Capital, Marital Status, and Income

ERIC Educational Resources Information Center

Cramm, J. M.; Moller, V.; Nieboer, A. P.

2012-01-01

Our study used multilevel regression analysis to identify individual- and neighbourhood-level factors that determine individual-level subjective well-being in Rhini, a deprived suburb of Grahamstown in the Eastern Cape province of South Africa. The Townsend index and Gini coefficient were used to investigate whether contextual neighbourhood-level…

COMMAND MODULE (C/M) - APOLLO/SATURN (A/S) MISSION 204 - SPACECRAFT (S/C) 012 - CAPE

NASA Image and Video Library

1967-01-28

Closeup view of the interior of Apollo S/C 012 C/M, Pad 34, showing the effects of the intense heat of the flash fire which killed the Prime Crew of the A/S 204 Mission. CAPE KENNEDY, FL CAPE KENNEDY, FL

Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Sae-Gwang; Lee, Da-Young; Seo, Su-Kil

Caffeic acid phenethyl ester (CAPE) is an active component of honeybee propolis extracts. It has several positive effects, including anti-inflammatory, anti-oxidation, anti-cancer, anti-bacterial, anti-viral, anti-fungal, and immunomodulatory effects. In particular, the suppressive effect of NF-{kappa}B may disrupt a component of allergic induction. The principal objective of this experimental study was to evaluate the effects of CAPE on the active systemic anaphylaxis induced by ovalbumin (OVA) challenge in mice. Mice were intraperitoneally sensitized and intravenously challenged with OVA. Histopathological analysis, nuclear factor (NF)-{kappa}B activation, and the plasma levels of histamine and total IgE after allergen challenge were evaluated. After challenges, allmore » of the sham-treated mice developed anaphylactic symptoms, increased plasma levels of histamine and OVA-specific IgE, marked vascular leakage, NF-{kappa}B activation, platelet-activating factor (PAF) production, and histological changes including pulmonary edema and hemorrhage in the renal medullae within 20 min. By way of contrast, a reduction in the plasma levels of histamine and OVA-specific IgE and an inhibition of NF-{kappa}B activation and PAF release were observed in the CAPE-treated mice. In addition, a significant prevention of hemoconcentration and OVA-induced pathological changes were noted. These results indicate that CAPE demonstrates an anti-allergic effect, which may be the result of its protective effects against IgE-mediated allergy.« less

A novel antioxidant agent caffeic acid phenethyl ester prevents long-term mobile phone exposure-induced renal impairment in rat. Prognostic value of malondialdehyde, N-acetyl-beta-D-glucosaminidase and nitric oxide determination.

PubMed

Ozguner, Fehmi; Oktem, Faruk; Ayata, Ali; Koyu, Ahmet; Yilmaz, H Ramazan

2005-09-01

Caffeic acid phenethyl ester (CAPE), a flavonoid like compound, is one of the major components of honeybee propolis. It has been used in folk medicine for many years in Middle East countries. It was found to be a potent free radical scavenger and antioxidant recently. The aim of this study was to examine long-term applied 900 MHz emitting mobile phone-induced oxidative stress that promotes production of reactive oxygen species (ROS) and, was to investigate the role of CAPE on kidney tissue against the possible electromagnetic radiation (EMR)-induced renal impairment in rats. In particular, the ROS such as superoxide and nitric oxide (NO) may contribute to the pathophysiology of EMR-induced renal impairment. Malondialdehyde (MDA, an index of lipid peroxidation) levels, urinary N-acetyl-beta-D-glucosaminidase (NAG, a marker of renal tubular injury) and nitric oxide (NO, an oxidant product) levels were used as markers of oxidative stress-induced renal impairment and the success of CAPE treatment. The activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) in renal tissue were determined to evaluate the changes of antioxidant status. The rats used in the study were randomly grouped (10 each) as follows: i) Control group (without stress and EMR), ii) Sham-operated rats stayed without exposure to EMR (exposure device off), iii) Rats exposed to 900 MHz EMR (EMR group), and iv) A 900 MHz EMR exposed + CAPE treated group (EMR + CAPE group). In the EMR exposed group, while tissue MDA, NO levels and urinary NAG levels increased (p < 0.0001), the activities of SOD, CAT, and GSH-Px in renal tissue were reduced (p < 0.001). CAPE treatment reversed these effects as well (p < 0.0001, p < 0.001 respectively). In conclusion, the increase in NO and MDA levels of renal tissue, and in urinary NAG with the decrease in renal SOD, CAT, GSH-Px activities demonstrate the role of oxidative mechanisms in 900 MHz mobile phone-induced renal tissue damage, and CAPE, via its free radical scavenging and antioxidant properties, ameliorates oxidative renal damage. These results strongly suggest that CAPE exhibits a protective effect on mobile phone-induced and free radical mediated oxidative renal impairment in rats.

A multi-level analysis of risk perception, poverty and sexual risk-taking among young people in Cape Town, South Africa.

PubMed

Tenkorang, Eric Y; Maticka-Tyndale, Eleanor; Rajulton, Fernando

2011-03-01

Various studies have underscored the relevance of community-level factors to sexual behavior and HIV/AIDS prevention efforts in Africa. However, there is a paucity of research and theorizing in this area compared to the preponderance of prevention models that focus solely on individual-level factors. Using data from the Cape Area Panel Survey and hierarchical linear models, this study examines the effects of a combination of individual-level factors and community-level poverty on sexual behaviors. Male and female respondents who perceived themselves to be at great risk of HIV infection were less likely to indulge in risky sexual behaviors. For females, race and community-level poverty were confounded such that race mediated the effects of community-level poverty. Results from this study indicate that multiple rationalities affect sexual behaviors in Cape Town, South Africa and that there is a need to consider both the social embeddedness of sexual behaviors and the rational components of decision making when designing HIV/AIDS prevention programs. Copyright © 2010 Elsevier Ltd. All rights reserved.

Influence of electromagnetic fields and protective effect of CAPE on bone mineral density in rats.

PubMed

Yildiz, Mustafa; Cicek, Ekrem; Cerci, Sevim Sureyya; Cerci, Celal; Oral, Baha; Koyu, Ahmet

2006-10-01

Most mobile phones emit electromagnetic radiation at 900 MHz or 1800 MHz. An electromagnetic field has some biological effects on the behavior of the cell population of bone. The aim of this work is to evaluate the effects of the radiation emitted by mobile phones on bone mineral density (BMD). The effects of caffeic acid phenethyl ester (CAPE) on the radiation-induced changes were also investigated. In the study, 48 Sprague Dawley rats were used. Rats were divided into five groups as follows: control, irradiated with 900 MHz, irradiated with 900 MHz and treatment, irradiated with 1800 MHz, irradiated with 1800 MHz and treatment groups. The rats in the control group (first group) were left within the experimental setup during 30 min/day for 28 days without radiation exposure. Nine hundred-MHz radiation group was exposed to irradiate both second and third groups for 28 days (30 min/day); 1800-MHz radiation group was exposed to irradiate both fourth and fifth groups for 28 days (30 min/day). Third and fifth groups were also treated by CAPE for 28 days. Treatment groups received 10 microml/kg/day CAPE i.p. before the irradiation. Bone mineral densities were determined in all groups. BMD was found to be decreased in the irradiated groups and to be increased in the treatment groups. The changes were not significant (p >0.05).

Influence of drying temperature on dietary fibre, rehydration properties, texture and microstructure of Cape gooseberry (Physalis peruviana L.).

PubMed

Vega-Gálvez, Antonio; Zura-Bravo, Liliana; Lemus-Mondaca, Roberto; Martinez-Monzó, Javier; Quispe-Fuentes, Issis; Puente, Luis; Di Scala, Karina

2015-04-01

The effects of air drying temperature on dietary fibre, texture and microstructure of the Cape gooseberry fruits during convective dehydration in the range of 50-90 ºC were investigated. The ratio of insoluble dietary fibre to soluble dietary fibre was higher than 7:1 for all dehydrated samples. At 50 ºC tissue structure damage was evidenced leading to the maximum water holding capacity (47.4 ± 2.8 g retained water/100 g water) and the lowest rehydration ratio (1.15 ± 0.06 g absorbed water/g d.m.). Texture analysis showed effects of drying temperatures on TPA parameters. Changes in microstructure tissue were also observed at the studied drying temperatures. Hot air drying technology leads not only to fruit preservation but also increases and adds value to Cape gooseberry, an asset to develop new functional products.

Skylab investigation of the upwelling off the Northwest coast of Africa

NASA Technical Reports Server (NTRS)

Szekielda, K. H.; Suszkowski, D. J.; Tabor, P. S.

1975-01-01

The upwelling off the NW coast of Africa in the vicinity of Cape Blanc was studied in February - March 1974 from aircraft and in September 1973 from Skylab. The aircraft study was designed to determine the effectiveness of a differential radiometer in quantifying surface chlorophyll concentrations. Photographic images of the S190A Multispectral Camera and the S190B Earth Terrain Camera from Skylab were used to study distributional patterns of suspended material and to locate ocean color boundaries. The thermal channel of the S192 Multispectral Scanner was used to map sea-surface temperature distributions offshore of Cape Blanc. Correlating ocean color changes with temperature gradients is an effective method of qualitatively estimating biological productivity in the upwelling region off Africa.

Larvicidal activity against Aedes aegypti of Foeniculum vulgare essential oils from Portugal and Cape Verde.

PubMed

Rocha, Diara Kady; Matosc, Olivia; Novoa, Maria Teresa; Figueiredo, Ana Cristina; Delgado, Manuel; Moiteiro, Cristina

2015-04-01

Dengue is a potentially fatal mosquito-borne infection with 50 million cases per year and 2.5 billion people vulnerable to the disease. This major public health problem has recurrent epidemics in Latin America and occurred recently in Cape Verde and Madeira Island. The lack of anti-viral treatment or vaccine makes the control of mosquito vectors a high option to prevent virus transmission. Essential oil (EO) constituents can affect insect's behaviour, being potentially effective in pest control. The present study evaluated the potential use of Foenicultm vulgare (fennel) EO in the control of the dengue vector Aedes aegypti. EOs isolated from fennel aerial parts collected in Cape Verde and from a commercial fennel EO of Portugal were analysed by NMR, GC and GC-MS. trans-Anethole (32 and 30%, respectively), limonene (28 and 18%, respectively) and fenchone (10% in both cases) were the main compounds identified in the EOs isolated from fennel from Cape Verde and Portugal, respectively. The larvicidal activity of the EOs and its major constituents were evaluated, using WHO procedures, against third instar larvae ofAe. aegypti for 24 h. Pure compounds, such as limonene isomers, were also assayed. The lethal concentrations LC50, C90 and LC99 were determined by probit analysis using mortality rates of bioassays. A 99% mortality of Ae. aegypti larvae was estimated at 37.1 and 52.4 µL L-1 of fennel EOs from Cape Verde and Portugal, respectively. Bioassays showed that fennel EOs from both countries displayed strong larvicidal effect against Ae. aegypti, the Cape Verde EO being as active as one of its major constituents, (-)-limonene.

MOCHA - Multi-Study Ocean Acoustics Human Effects Analysis

DTIC Science & Technology

2012-09-30

trials on sperm whales, Bahamas BRS, SOCAL BRS, Norwegian 3S and 3S2, Cape Hatteras EK60 experiments and Cape Hatteras and Hawaiian killer whale BRS... hold a series of workshops that will be attended by the working group, steering group and project post-doctoral researchers. Each workshop will focus...and in this order for of a number of reasons, as follows. We have begun with deep divers (beaked whales and sperm whales) because this group contains

Evaluation of infection control advice for patients at risk of chemotherapy-induced neutropenia in 2 pediatric oncology centers: Cape Town, South Africa, and Newcastle-Upon-Tyne, UK.

PubMed

Woolner, Andrea Forman; Davidson, Alan; Skinner, Rod; King, Derek

2012-02-01

Childhood cancers are treated with myelotoxic chemotherapy. Resultant neutropenia can lead to life-threatening infections. There is no consistent guidance on infection control precautions for neutropenic patients who are not yet febrile or infected. Although it is not possible to eradicate infection risk, it is conceivable that the risk could be reduced by effective infection prevention. This study compared infection control measures advised to pediatric and adolescent oncology patients receiving chemotherapy in 2 centers (Cape Town, South Africa, and Newcastle, UK). Prospective, observational, cross-sectional surveys of staff and patients/parents were undertaken using standardized, study-specific questionnaires. Seventy-eight staff and 56 patients/parents participated. Precautions advised in Newcastle were significantly different to Cape Town (all P < .05), except both agreed inpatient isolation was unnecessary. Over 40% of patients/parents felt isolation was important (P < .01). In Cape Town, staff and patients had similar views. In Newcastle, patients/parents had stricter opinions on particular precautions than staff, for example, attending school, playing outside and avoiding busy places (P < .01). Patient/parent responses were similar between centers. Over 90% of staff felt advising patients/parents about hand washing was important. Currently infection prevention advice is inconsistent. Further research is needed to elucidate effective guidance for infection prevention in pediatric neutropenic patients.

Effects of propolis, caffeic acid phenethyl ester, and pollen on renal injury in hypertensive rat: An experimental and theoretical approach.

PubMed

Salmas, Ramin Ekhteiari; Gulhan, Mehmet Fuat; Durdagi, Serdar; Sahna, Engin; Abdullah, Huda I; Selamoglu, Zeliha

2017-08-01

The objective of this study was to evaluate the antioxidant effects of propolis, caffeic acid phenethyl ester (CAPE; active compound in propolis), and pollen on biochemical oxidative stress biomarkers in rat kidney tissue inhibited by N ω -nitro-L-arginine methyl ester (L-NAME). The biomarkers evaluated were paraoxonase (PON1), oxidative stress index (OSI), total antioxidant status (TAS), total oxidant status (TOS), asymmetric dimethylarginine (ADMA), and nuclear factor kappa B (NF-κB). TAS levels and PON1 activity were significantly decreased in kidney tissue samples in the L-NAME-treated group (P < 0.05). The levels of TAS and PONI were higher in the L-NAME plus propolis, CAPE, and pollen groups compared with the L-NAME-treated group. TOS, ADMA, and NF-κB levels were significantly increased in the kidney tissue samples of the L-NAME-treated group (P < 0.05). However, these parameters were significantly lower in the L-NAME plus propolis, CAPE, and pollen groups (P < 0.05) compared with rats administered L-NAME alone (P < 0.05). Furthermore, the binding energy of CAPE within catalytic domain of glutathione reductase (GR) enzyme as well as its inhibitory mechanism was determined using molecular modeling approaches. In conclusion, experimental and theoretical data suggested that oxidative alterations occurring in the kidney tissue of chronic hypertensive rats may be prevented via active compound of propolis, CAPE administration. Copyright © 2017 John Wiley & Sons, Ltd.

Metal exposure and effects in voles and small birds near a mining haul road in Cape Krusenstern National Monument, Alaska.

PubMed

Brumbaugh, William G; Mora, Miguel A; May, Thomas W; Phalen, David N

2010-11-01

Voles and small passerine birds were live-captured near the Delong Mountain Regional Transportation System (DMTS) haul road in Cape Krusenstern National Monument in northwest Alaska to assess metals exposure and sub-lethal biological effects. Similar numbers of animals were captured from a reference site in southern Cape Krusenstern National Monument for comparison. Histopathological examination of selected organs, and analysis of cadmium, lead, and zinc concentrations in liver and blood samples were performed. Voles and small birds captured from near the haul road had about 20 times greater blood and liver lead concentrations and about three times greater cadmium concentrations when compared to those from the reference site, but there were no differences in zinc tissue concentrations. One vole had moderate metastatic mineralization of kidney tissue, otherwise we observed no abnormalities in internal organs or DNA damage in the blood of any of the animals. The affected vole also had the greatest liver and blood Cd concentration, indicating that the lesion might have been caused by Cd exposure. Blood and liver lead concentrations in animals captured near the haul road were below concentrations that have been associated with adverse biological effects in other studies; however, subtle effects resulting from lead exposure, such as the suppression of the activity of certain enzymes, cannot be ruled out for some individual animals. Results from our 2006 reconnaissance-level study indicate that overall, voles and small birds obtained from near the DMTS road in Cape Krusenstern National Monument were not adversely affected by metals exposure; however, because of the small sample size and other uncertainties, continued monitoring of lead and cadmium in terrestrial habitats near the DMTS road is advised.

Metal exposure and effects in voles and small birds near a mining haul road in Cape Krusenstern National Monument, Alaska

USGS Publications Warehouse

Brumbaugh, William G.; Mora, Miguel A.; May, Thomas W.; Phalen, David N.

2010-01-01

Voles and small passerine birds were live-captured near the Delong Mountain Regional Transportation System (DMTS) haul road in Cape Krusenstern National Monument in northwest Alaska to assess metals exposure and sub-lethal biological effects. Similar numbers of animals were captured from a reference site in southern Cape Krusenstern National Monument for comparison. Histopathological examination of selected organs, and analysis of cadmium, lead, and zinc concentrations in liver and blood samples were performed. Voles and small birds captured from near the haul road had about 20 times greater blood and liver lead concentrations and about three times greater cadmium concentrations when compared to those from the reference site, but there were no differences in zinc tissue concentrations. One vole had moderate metastatic mineralization of kidney tissue, otherwise we observed no abnormalities in internal organs or DNA damage in the blood of any of the animals. The affected vole also had the greatest liver and blood Cd concentration, indicating that the lesion might have been caused by Cd exposure. Blood and liver lead concentrations in animals captured near the haul road were below concentrations that have been associated with adverse biological effects in other studies; however, subtle effects resulting from lead exposure, such as the suppression of the activity of certain enzymes, cannot be ruled out for some individual animals. Results from our 2006 reconnaissance-level study indicate that overall, voles and small birds obtained from near the DMTS road in Cape Krusenstern National Monument were not adversely affected by metals exposure; however, because of the small sample size and other uncertainties, continued monitoring of lead and cadmium in terrestrial habitats near the DMTS road is advised.

Reconstruction of major maternal and paternal lineages of the Cape Muslim population

PubMed Central

Isaacs, Shafieka; Geduld-Ullah, Tasneem; Benjeddou, Mongi

2013-01-01

The earliest Cape Muslims were brought to the Cape (Cape Town - South Africa) from Africa and Asia from 1652 to 1834. They were part of an involuntary migration of slaves, political prisoners and convicts, and they contributed to the ethnic diversity of the present Cape Muslim population of South Africa. The history of the Cape Muslims has been well documented and researched however no in-depth genetic studies have been undertaken. The aim of the present study was to determine the respective African, Asian and European contributions to the mtDNA (maternal) and Y-chromosomal (paternal) gene pool of the Cape Muslim population, by analyzing DNA samples of 100 unrelated Muslim males born in the Cape Metropolitan area. A panel of six mtDNA and eight Y-chromosome SNP markers were screened using polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP). Overall admixture estimates for the maternal line indicated Asian (0.4168) and African mtDNA (0.4005) as the main contributors. The admixture estimates for the paternal line, however, showed a predominance of the Asian contribution (0.7852). The findings are in accordance with historical data on the origins of the early Cape Muslims. PMID:23885197

Reliability and Validity of the Turkish Version of the Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V).

PubMed

Özcebe, Esra; Aydinli, Fatma Esen; Tiğrak, Tuğçe Karahan; İncebay, Önal; Yilmaz, Taner

2018-01-11

The main purpose of this study was to culturally adapt the Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) to Turkish and to evaluate its internal consistency, validity, and reliability. The Turkish version of CAPE-V was developed, and with the use of a prospective case-control design, the voice recordings of 130 participants were collected according to CAPE-V protocol. Auditory-perceptual evaluation was conducted according to CAPE-V and Grade, Roughness, Breathiness, Asthenia, and Strain (GRBAS) scale by two ear, nose, and throat specialists and two speech and language therapists. The different types of voice disorders, classified as organic and functional disorders, were compared in terms of their CAPE-V scores. The overall severity parameter had the highest intrarater and inter-reliability values for all the participants. For all four raters, the differences in the six CAPE-V parameters between the study and the control groups were found to be statistically significant. Among the correlations for the comparable parameters of the CAPE-V and the GRBAS scales, the highest correlation was found between the overall severity-grade parameters. There was no difference found between the organic and functional voice disorders in terms of the CAPE-V scores. The Turkish version of CAPE-V has been proven to be a reliable and valid instrument to use in the auditory-perceptual evaluation of voice. For the future application of this study, it would be important to investigate whether cepstral measures correlate with the auditory-perceptual judgments of dysphonia severity collected by a Turkish version of the CAPE-V. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

Apunipima baby basket program: a retrospective cost study.

PubMed

Edmunds, Kim; Searles, Andrew; Neville, Johanna; Ling, Rod; McCalman, Janya; Mein, Jacki

2016-11-03

The Baby Basket initiative was developed by Apunipima Cape York Health Council (ACYHC) to address poor maternal and child health (MCH) in Cape York, the northernmost region of Queensland. While positive outcomes for Indigenous MCH programs are reported in the literature, few studies have a strong evidence base or employ a sound methodological approach to evaluation. The aim of the cost study is to identify the resources required to deliver the Baby Basket program in the remote communities of Cape York. It represents an initial step in the economic evaluation of the Apunipima Baby Basket program. The aim of this study was to report whether the current program represents an effective use of scarce resources. The cost study was conducted from the perspective of the health providers and reflects the direct resources required to deliver the Baby Basket program to 170 women across 11 communities represented by ACYHC. A flow diagram informed by interviews with ACYHC staff, administrative documents and survey feedback was used to map the program pathway and measure resource use. Monetary values, in 2013 Australian dollars, were applied to the resources used to deliver the Baby Basket program for one year. The total cost of delivering the Baby Basket progam to 170 participants in Cape York was $148,642 or approximately, $874 per participant. The analysis allowed for the cost of providing the Baby Baskets to remote locations and the time for health workers to engage with women and thereby encourage a relationship with the health service. Routinely collected data showed improved engagement between expectant women and the health service during the life of the program. The Apunipima Baby Basket cost study identifies the resources required to deliver this program in remote communities of Cape York and provides a framework that will support prospective data collection of more specific outcome data, for future cost-effectiveness analyses and cost-benefit analyses. An investment of $874 per Baby Basket participant was associated with improved engagement with the health service, an important factor in maternal and child health.

Metabolomics study of cadmium-induced diabetic nephropathy and protective effect of caffeic acid phenethyl ester using UPLC-Q-TOF-MS combined with pattern recognition.

PubMed

Gong, Pin; Chang, Xiangna; Chen, Xuefeng; Bai, Xiaohuan; Wen, He; Pi, Sihui; Yang, Wenjuan; Wang, Lan; Chen, Fuxin

2017-09-01

Diabetic nephropathy (DN) is the most severe complication of diabetes and multiple factors are involved in the pathogenesis of DN. Among them, cadmium (Cd) acts as a risk factor inducing the occurrence of DN. The present study focused on investigating the protective role of caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives, against Cd-induced DN in mice based on ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS)and pattern recognition. Serum and urine biochemical indexes were detected and histopathological observation has been done to evaluate the damage of Cd on animals. Moreover, the global serum profiles of different groups were distinguished by UPLC-Q-TOF-MS and principal component analysis (PCA) were applied for group differentiation and marker selection. Moreover, the influence of Cd on the oxidative status in DN mice were also evaluated by assessing the parameters of oxidative stress, proinflammatory cytokines and antioxidant competence. As shown in the scores plots, the distinct clustering among controls, DN and CAPE groups were observed, significant changes in serum levels of LysoPC(18:1(11Z)), 2,3-dinor-8-iso-PGF2a, PS(18:1(9Z)/18:1(9Z)), DG(17:0/22:4 (7Z,10Z, 13Z, 16Z)/0:0) and Arachidonic acid(AA) were noted and identified as potential biomarkers, the effect of CAPE reverted them back to near normalcy. Further, It was observed a significant improvement in lipid peroxides (LPO) and protein carbonyls (PCO) levels in Cd-induced DN kidneys along with a significant decline in superoxide dismutase (SOD), catalase (CAT), and reduced glutathione (GSH) levels, however, CAPE relieved these changes. In conclusion, the study suggested that the pathogenesis of DN caused by Cd probably owes to the perturbations of lipid metabolism and AA metabolism; CAPE seems to be effective agent and may be related to its potent antioxidant, anti-inflammatory properties and action as an Nrf2 activator. Copyright © 2017 Elsevier B.V. All rights reserved.

Comparative evaluation of antibacterial activity of caffeic acid phenethyl ester and PLGA nanoparticle formulation by different methods

NASA Astrophysics Data System (ADS)

Arasoglu, Tülin; Derman, Serap; Mansuroglu, Banu

2016-01-01

The aim of the present study was to evaluate the antimicrobial activity of nanoparticle and free formulations of the CAPE compound using different methods and comparing the results in the literature for the first time. In parallel with this purpose, encapsulation of CAPE with the PLGA nanoparticle system (CAPE-PLGA-NPs) and characterization of nanoparticles were carried out. Afterwards, antimicrobial activity of free CAPE and CAPE-PLGA-NPs was determined using agar well diffusion, disk diffusion, broth microdilution and reduction percentage methods. P. aeroginosa, E. coli, S. aureus and methicillin-resistant S. aureus (MRSA) were chosen as model bacteria since they have different cell wall structures. CAPE-PLGA-NPs within the range of 214.0 ± 8.80 nm particle size and with an encapsulation efficiency of 91.59 ± 4.97% were prepared using the oil-in-water (o-w) single-emulsion solvent evaporation method. The microbiological results indicated that free CAPE did not have any antimicrobial activity in any of the applied methods whereas CAPE-PLGA-NPs had significant antimicrobial activity in both broth dilution and reduction percentage methods. CAPE-PLGA-NPs showed moderate antimicrobial activity against S. aureus and MRSA strains particularly in hourly measurements at 30.63 and 61.25 μg ml-1 concentrations (both p < 0.05), whereas they failed to show antimicrobial activity against Gram-negative bacteria (P. aeroginosa and E. coli, p > 0.05). In the reduction percentage method, in which the highest results of antimicrobial activity were obtained, it was observed that the antimicrobial effect on S. aureus was more long-standing (3 days) and higher in reduction percentage (over 90%). The appearance of antibacterial activity of CAPE-PLGA-NPs may be related to higher penetration into cells due to low solubility of free CAPE in the aqueous medium. Additionally, the biocompatible and biodegradable PLGA nanoparticles could be an alternative to solvents such as ethanol, methanol or DMSO. Consequently, obtained results show that the method of selection is extremely important and will influence the results. Thus, broth microdilution and reduction percentage methods can be recommended as reliable and useful screening methods for determination of antimicrobial activity of PLGA nanoparticle formulations used particularly in drug delivery systems compared to both agar well and disk diffusion methods.

Validation of the Spanish adaptation of the Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V).

PubMed

Núñez-Batalla, Faustino; Morato-Galán, Marta; García-López, Isabel; Ávila-Menéndez, Arántzazu

2015-01-01

The Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) was developed.to promote a standardised approach to evaluating and documenting auditory perceptual judgments of vocal quality. This tool was originally developed in English language and its Spanish version is still inexistent. The aim of this study was to develop a Spanish adaptation of CAPE-V and to examine the reliability and empirical validity of this Spanish version. To adapt the CAPE-V protocol to the Spanish language, we proposed 6 phrases phonetically designed according to the CAPE-V requirements. Prospective instrument validation was performed. The validity of the Spanish version of the CAPE-V was examined in 4 ways: intra-rater reliability, inter-rater reliability and CAPE-V versus GRABS judgments. Inter-rater reliability coefficients for the CAPE-V ranged from 0.93 for overall severity to 0.54 for intensity; intra-rater reliability ranged from 0.98 for overall severity to 0.85 for intensity. The comparison of judgments between GRABS and CAPE-V ranged from 0.86 for overall severity to 0.61 for breathiness. The present study supports the use of the Spanish version of CAPE-V because of its validity and reliability. Copyright © 2014 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial. All rights reserved.

Effects of Caffeic Acid Phenethyl Ester and 4-Vinylcatechol on the Stabilities of Oil-in-Water Emulsions of Stripped Soybean Oil.

PubMed

Jia, Cai-Hua; Shin, Jung-Ah; Lee, Ki-Teak

2015-12-02

Caffeic acid phenethyl ester (CAPE) and 4-vinylcatechol (4-VC) were prepared for studying their antioxidative activities in emulsion. Oil-in-water emulsions of stripped soybean oil containing 200 ppm of CAPE, 4-VC, or α-tocopherol were stored at 40 °C in the dark for 50 days, and proton nuclear magnetic resonance ((1)H NMR) was used to identify and quantify the oxidation products. Emulsion droplet sizes, peroxide values, and levels of primary oxidation products (i.e., hydroperoxides) and secondary oxidation products (i.e., aldehydes) were determined. The results showed that CAPE (200 ppm) and 4-VC (200 ppm) had significantly greater antioxidant activities on the oxidation of stripped soybean oil-in-water emulsions than α-tocopherol (200 ppm). The peroxide values of CAPE (8.4 mequiv/L emulsion) and 4-VC (15.0 mequiv/L emulsion) were significantly lower than that of α-tocopherol (33.4 mequiv/L emulsion) (p < 0.05) on 36 days. In addition, the combinations of CAPE + α-tocopherol (100 + 100 ppm) or 4-VC + α-tocopherol (100 + 100 ppm) had better antioxidant activities than α-tocopherol (200 ppm). For CAPE + α-tocopherol, 4-VC + α-tocopherol, and α-tocopherol, the amounts of conjugated diene forms were 16.67, 13.72, and 16.32 mmol/L emulsion, and the concentrations of aldehydes were 2.15, 1.13, and 4.26 mmol/L emulsion, respectively, after 50 days of storage.

Regional ontogeny of New England salt marsh die-off.

PubMed

Coverdale, Tyler C; Bertness, Mark D; Altieri, Andrew H

2013-10-01

Coastal areas are among the world's most productive and highly affected ecosystems. Centuries of human activity on coastlines have led to overexploitation of marine predators, which in turn has led to cascading ecosystem-level effects. Human effects and approaches to mediating them, however, differ regionally due to gradients in biotic and abiotic factors. Salt marsh die-off on Cape Cod, Massachusetts (U.S.A.), triggered by a recreational-fishing-induced trophic cascade that has released herbivorous crabs from predator control, has been ongoing since 1976. Similar salt marsh die-offs have been reported in Long Island Sound and Narragansett Bay (U.S.A.), but the driving mechanism of these die-offs has not been examined. We used field experiments to assess trophic interactions and historical reconstructions of 24 New England marshes to test the hypotheses that recreational fishing and predator depletion are a regional trigger of salt marsh die-off in New England and that die-offs in Long Island Sound and Narragansett Bay are more recent than those on Cape Cod. Predator depletion was the general trigger of marsh die-off and explained differences in herbivorous crab abundance and the severity of die-off across regions. Die-offs in Long Island Sound and Narragansett Bay are following a trajectory similar to die-off on Cape Cod, but are approximately 20 years behind those on Cape Cod. As a result, die-off currently affects 31.2% (SE 2.2) of low-marsh areas in Long Island Sound and Narragansett Bay, less than half the severity of die-off on Cape Cod. Our results contribute to the growing evidence that recreational fishing is an increasing threat to coastal ecosystems and that studying the effects of human activity at regional scales can provide insight into local effects and aid in early detection and potential remediation. © 2013 Society for Conservation Biology.

Clausius-Clapeyron Scaling of Convective Available Potential Energy (CAPE) in Cloud-Resolving Simulations

NASA Astrophysics Data System (ADS)

Seeley, J.; Romps, D. M.

2015-12-01

Recent work by Singh and O'Gorman has produced a theory for convective available potential energy (CAPE) in radiative-convective equilibrium. In this model, the atmosphere deviates from a moist adiabat—and, therefore, has positive CAPE—because entrainment causes evaporative cooling in cloud updrafts, thereby steepening their lapse rate. This has led to the proposal that CAPE increases with global warming because the strength of evaporative cooling scales according to the Clausius-Clapeyron (CC) relation. However, CAPE could also change due to changes in cloud buoyancy and changes in the entrainment rate, both of which could vary with global warming. To test the relative importance of changes in CAPE due to CC scaling of evaporative cooling, changes in cloud buoyancy, and changes in the entrainment rate, we subject a cloud-resolving model to a suite of natural (and unnatural) forcings. We find that CAPE changes are primarily driven by changes in the strength of evaporative cooling; the effect of changes in the entrainment rate and cloud buoyancy are comparatively small. This builds support for CC scaling of CAPE.

Science for the stewardship of the groundwater resources of Cape Cod, Massachusetts

USGS Publications Warehouse

Barbaro, Jeffrey R.; Masterson, John P.; LeBlanc, Denis R.

2014-01-01

Groundwater is the sole source of drinking water and a major source of freshwater for domestic, industrial, and agricultural uses on Cape Cod, Massachusetts. Groundwater discharged from aquifers also supports freshwater pond and stream ecosystems and coastal wetlands. Six hydraulically distinct groundwater-flow systems (lenses) have been delineated on Cape Cod. Of the approximately 450 million gallons per day of water that enters these lenses as recharge from precipitation, about 69 percent discharges directly to the coast, about 24 percent discharges to streams, and almost 7 percent is withdrawn by public-supply wells. In most areas, groundwater in the sand and gravel aquifers is shallow and susceptible to contamination from anthropogenic sources and saltwater intrusion. Continued land development and population growth on Cape Cod have created concerns that potable water will become less available and that the quantity and quality of water flowing to natural discharge areas such as ponds, streams, and coastal waters will continue to decline. The U.S. Geological Survey (USGS) has been investigating groundwater and surface-water resources on Cape Cod for more than 50 years. Recent studies highlighted in this fact sheet have focused on the sources of water to public-supply wells, ponds, streams, and coastal areas; the transport and discharge of nitrogen derived from domestic and municipal disposal of wastewater; and the effects of climate change on groundwater and surface-water resources. Other USGS activities include long-term monitoring of groundwater and pond levels and field research on groundwater contamination at the USGS Cape Cod Toxic Substances Hydrology Research Site (http://ma.water.usgs.gov/MMRCape/) near the Joint Base Cape Cod (JBCC), formerly the Massachusetts Military Reservation.

Caffeic acid phenethyl ester protects kidneys against acetylsalicylic acid toxicity in rats.

PubMed

Bozkurt, Yasar; Bozkurt, Mehtap; Turkçu, Gul; Sancaktutar, Ahmet Ali; Soylemez, Haluk; Penbegul, Necmettin; Atar, Murat; Bodakcı, Mehmet Nuri; Hatipoglu, Namık Kemal; Yuksel, Hatice; Kıbrıslı, Erkan; Yavuz, Celal

2012-01-01

The aim of this study was to investigate the protective effect of caffeic acid phenethyl ester (CAPE) on acetylsalicylic acid (ASA)-induced renal damage in rats. A total of 40 rats were randomly divided into five groups, with eight rats in each group-group 1: control, not receiving any medication; group 2: ASA (50 mg/kg/day); group 3: ASA (50 mg/kg/day) + CAPE (20 μg/kg/day); group 4: ASA (100 mg/kg/day); and group 5: ASA (100 mg/kg/day) + CAPE (20 μg/kg/day). ASA and CAPE were given via orogastric gavage for 5 days. The total oxidant status (TOS), total antioxidant capacity (TAC), and paraoxonase-1 (PON-1) activity of the blood samples and kidney tissues were determined. Histopathological examinations of the kidneys were performed using light microscopic methods. The TOS level in the serum of rats and kidney tissues given ASA (groups 2 and 4) significantly increased, but the levels of TAC and PON-1 in these tissues significantly decreased in group 4 when compared with the control rats (p < 0.05). The levels of TAC and PON-1 in the kidney tissues increased and the levels of TOS decreased in the CAPE treatment groups (groups 3 and 5) when compared with the rats in the no CAPE treatment groups (groups 2 and 4). The PON-1, TAC, and TOS values reverted to normal levels in group 5 when compared to group 4 (p < 0.05). These results were supported by histopathological observation. Oxidative stress plays an important role in ASA-induced nephrotoxicity, and CAPE may protect against ASA-induced nephrotoxicity in rats.

Applications of ichnology to hydrogeology, with examples from the Cape Fear Formation (Cretaceous), South Carolina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martin, A.J.; Simones, G.C.

Ichnology, the study of modern and ancient traces left by organisms, has provided supplemental information to geologic subdisciplines such as sedimentology and stratigraphy. The major objective of the authors paper is to emphasize the valuable information that can be conveyed by trace fossils in the investigation of hydrogeologic units. Bioturbation has a net effect of mixing different types and layers of sediments, such as introducing clays into sands and vice versa. This mixing can decrease porosity and permeability of sandy units, thus changing potential aquifers into confining units. For example, a sandy fluvial deposit will contain distinctive nonmarine trace fossils,more » thus defining channel sands that may serve as permeable conduits for ground-water flow. In contrast, a sandy shelf deposit will contain marine trace fossils in a sand body geometry that will be markedly different from aquifers produced in nonmarine environments. Bioturbation also causes geochemical and diagenetic changes in sediments, causing irrigation of previously anoxic sediments and precipitation of ion oxides. The Cretaceous Cape Fear Formation of the Atlantic Coastal Plain, in the subsurface of South Carolina, is presented as an example of a hydrogeologic unit that has been reinterpreted using ichnologic data. Extensive bioturbation caused mixing of clays and sands in Cape Fear sediments, which resulted in the Cape Fear becoming a regional confining system. Trace fossil assemblages indicate a brackish water environment, perhaps estuarine, for the Cape Fear, as opposed to previous interpretations of fluvial and deltaic environments. Bioturbated zones also have significantly more oxidized iron than unbioturbated zones, highlighting potential effects on ground-water quality.« less

Abiotic versus biotic drivers of ocean pH variation under fast sea ice in McMurdo Sound, Antarctica.

PubMed

Matson, Paul G; Washburn, Libe; Martz, Todd R; Hofmann, Gretchen E

2014-01-01

Ocean acidification is expected to have a major effect on the marine carbonate system over the next century, particularly in high latitude seas. Less appreciated is natural environmental variation within these systems, particularly in terms of pH, and how this natural variation may inform laboratory experiments. In this study, we deployed sensor-equipped moorings at 20 m depths at three locations in McMurdo Sound, comprising deep (bottom depth>200 m: Hut Point Peninsula) and shallow environments (bottom depth ∼25 m: Cape Evans and New Harbor). Our sensors recorded high-frequency variation in pH (Hut Point and Cape Evans only), tide (Cape Evans and New Harbor), and water mass properties (temperature and salinity) during spring and early summer 2011. These collective observations showed that (1) pH differed spatially both in terms of mean pH (Cape Evans: 8.009±0.015; Hut Point: 8.020±0.007) and range of pH (Cape Evans: 0.090; Hut Point: 0.036), and (2) pH was not related to the mixing of two water masses, suggesting that the observed pH variation is likely not driven by this abiotic process. Given the large daily fluctuation in pH at Cape Evans, we developed a simple mechanistic model to explore the potential for biotic processes--in this case algal photosynthesis--to increase pH by fixing carbon from the water column. For this model, we incorporated published photosynthetic parameters for the three dominant algal functional groups found at Cape Evans (benthic fleshy red macroalgae, crustose coralline algae, and sea ice algal communities) to estimate oxygen produced/carbon fixed from the water column underneath fast sea ice and the resulting pH change. These results suggest that biotic processes may be a primary driver of pH variation observed under fast sea ice at Cape Evans and potentially at other shallow sites in McMurdo Sound.

Abiotic versus Biotic Drivers of Ocean pH Variation under Fast Sea Ice in McMurdo Sound, Antarctica

PubMed Central

Matson, Paul G.; Washburn, Libe; Martz, Todd R.; Hofmann, Gretchen E.

2014-01-01

Ocean acidification is expected to have a major effect on the marine carbonate system over the next century, particularly in high latitude seas. Less appreciated is natural environmental variation within these systems, particularly in terms of pH, and how this natural variation may inform laboratory experiments. In this study, we deployed sensor-equipped moorings at 20 m depths at three locations in McMurdo Sound, comprising deep (bottom depth>200 m: Hut Point Peninsula) and shallow environments (bottom depth ∼25 m: Cape Evans and New Harbor). Our sensors recorded high-frequency variation in pH (Hut Point and Cape Evans only), tide (Cape Evans and New Harbor), and water mass properties (temperature and salinity) during spring and early summer 2011. These collective observations showed that (1) pH differed spatially both in terms of mean pH (Cape Evans: 8.009±0.015; Hut Point: 8.020±0.007) and range of pH (Cape Evans: 0.090; Hut Point: 0.036), and (2) pH was not related to the mixing of two water masses, suggesting that the observed pH variation is likely not driven by this abiotic process. Given the large daily fluctuation in pH at Cape Evans, we developed a simple mechanistic model to explore the potential for biotic processes – in this case algal photosynthesis – to increase pH by fixing carbon from the water column. For this model, we incorporated published photosynthetic parameters for the three dominant algal functional groups found at Cape Evans (benthic fleshy red macroalgae, crustose coralline algae, and sea ice algal communities) to estimate oxygen produced/carbon fixed from the water column underneath fast sea ice and the resulting pH change. These results suggest that biotic processes may be a primary driver of pH variation observed under fast sea ice at Cape Evans and potentially at other shallow sites in McMurdo Sound. PMID:25221950

Perspectives on quality mental health care from Brazilian and Cape Verdean outpatients: implications for effective patient-centered policies and models of care.

PubMed

De Jesus, Maria; Earl, Tara R

2014-01-01

Mental health providers are increasingly coming into contact with large and growing multi-racial/ethnic and immigrant patient populations in the United States. Knowledge of patient perspectives on what constitutes quality mental health care is necessary for these providers. The aim of this study was to identify indicators of quality of mental health care that matter most to two underrepresented immigrant patient groups of Portuguese background: Brazilians and Cape Verdeans. A qualitative design was adopted using focus group discussions. Six focus groups of patients (n=24 Brazilians; n=24 Cape Verdeans) who received outpatient mental health treatment through public safety net clinics in the northeast region of the United States were conducted. The Consensual Qualitative Research analytic method allowed us to identify three quality of care domains: provider performance, aspects of mental health care environment, and effectiveness of mental health care treatment. Provider performance was associated with five categories: relational, communication, linguistic, cultural, and technical competencies. Aspects of mental health care environment were linked to two categories: psychosocial and physical environment. Effectiveness of mental health care treatment was related to two categories: therapeutic relationship and treatment outcomes. Study findings provide useful data for the development of more culturally appropriate and effective patient-centered models and policies in mental health care.

Perspectives on quality mental health care from Brazilian and Cape Verdean outpatients: Implications for effective patient-centered policies and models of care

PubMed Central

De Jesus, Maria; Earl, Tara R.

2014-01-01

Mental health providers are increasingly coming into contact with large and growing multi-racial/ethnic and immigrant patient populations in the United States. Knowledge of patient perspectives on what constitutes quality mental health care is necessary for these providers. The aim of this study was to identify indicators of quality of mental health care that matter most to two underrepresented immigrant patient groups of Portuguese background: Brazilians and Cape Verdeans. A qualitative design was adopted using focus group discussions. Six focus groups of patients (n=24 Brazilians; n=24 Cape Verdeans) who received outpatient mental health treatment through public safety net clinics in the northeast region of the United States were conducted. The Consensual Qualitative Research analytic method allowed us to identify three quality of care domains: provider performance, aspects of mental health care environment, and effectiveness of mental health care treatment. Provider performance was associated with five categories: relational, communication, linguistic, cultural, and technical competencies. Aspects of mental health care environment were linked to two categories: psychosocial and physical environment. Effectiveness of mental health care treatment was related to two categories: therapeutic relationship and treatment outcomes. Study findings provide useful data for the development of more culturally appropriate and effective patient-centered models and policies in mental health care. PMID:24461570

Cape Verdeans in America: Our Story. A Teachers Manual.

ERIC Educational Resources Information Center

Almeida, Raymond A.; And Others

Teaching strategies are suggested to help high school social studies teachers develop and implement a study of Cape Verdean American history. Intended as a guide to accompany "Cape Verdeans in America," (SO 011 060), the teacher's manual offers three categories of teaching methods: (1) ideas to help students read and understand the book,…

Midlatitude Storm Potential in a Changing Climate

NASA Astrophysics Data System (ADS)

Seeley, J.; Romps, D. M.

2013-12-01

The effect of climate change on severe weather over the continental U.S. is calculated using CMIP5 output from ten GCMs. The potential for severe weather is evaluated in these models using an operational proxy of CAPE times shear; the calculation of CAPE is made possible by the presence of high-frequency data in the CMIP5 archive that was not available in CMIP3. First, the ability of each GCM to replicate modern-day distributions of CAPE and shear is assessed. It is found that the GCMs replicate the observed seasonal cycle of CAPE with reasonable fidelity, but a majority of the GCMs show an erroneous summertime CAPE maximum on the East Coast. The source of this persistent bias is explored. Second, the predicted changes in future severe-storm potential over the continental U.S. are evaluated using the RCP4.5 emissions scenario. The seasonal cycle of domain-averaged undilute CAPE over CONUS for 10 GCMs and radiosonde measurements. Data is averaged over the recent past ("RP") period of 1999-2008. Summertime (JJA) climatologies of CAPE over CONUS for 10 GCMs and radiosonde observations. Data is averaged over the recent past ("RP") period of 1999-2008. Six of the models show an erroneous CAPE maximum on the East Coast.

Is caffeic acid phenethyl ester more protective than doxycycline in experimental periodontitis?

PubMed

Yiğit, Umut; Kırzıoğlu, Fatma Yeşim; Uğuz, Abdülhadi Cihangir; Nazıroğlu, Mustafa; Özmen, Özlem

2017-09-01

Host modulation therapies (anti-inflammatory drugs, bone-stimulating agents, anti-proteinase etc.) target the inhibition or stabilization of tissue breakdown. The aim of the present study was to evaluate the effects of caffeic acid phenethyl ester (CAPE) and/or low dose doxycycline (LDD) administrations on alveolar bone loss (ABL), serum cytokines and gingival apoptosis, as well as the levels of oxidants and anti-oxidants in rats with ligature-induced periodontitis. The animals were randomly divided into five groups: Group C (periodontally healthy), Group PC (Periodontitis+CAPE), Group PD (Periodontitis+LDD), Group PCD (Periodontitis+CAPE+LDD), Group P (Periodontitis). Experimental periodontitis was induced for 14days. Levels of ABL, and the serum cytokines, interleukin (IL)-1 β, IL-6, tumor necrosis factor-α (TNF-α) and IL-10 were assessed as were the levels of the oxidants and anti-oxidants, malondialdehyde (MDA), glutathione (GSH) and glutathione peroxidase (GSH-Px), and levels of gingival apoptosis. The lowest ABL levels was evident in the PC group, among the experimental groups. There was also less inflammatory infiltration in the PC group than the PD group. IL-1β, IL-6, and IL-10 were lower in the PC group and higher in the P group in comparison to the levels in the other experiment groups. TNF-α levels in the PD group were higher than levels in the PC and PCD groups. The PC and PCD groups did not differ from the C group in regard to MDA levels. The highest GSH-Px level was found in the PC group. Gingival apoptosis in the PC group was not only lower than the PD and PCD groups, but also lower than in the C group. The present study suggests that CAPE has more anti-inflammatory, anti-oxidant and anti-apoptotic effects than LDD, with no additive benefits of a CAPE+LDD combination being evident in rats with periodontitis. Copyright © 2017 Elsevier Ltd. All rights reserved.

A predictive risk model for electroshock-induced mortality of the endangered Cape Fear shiner

USGS Publications Warehouse

Holliman, F.M.; Reynolds, J.B.; Kwak, T.J.

2003-01-01

We evaluated the effects of a single electroshock on injury and mortality of hatchery-reared Cape Fear shiners Notropis mekistocholas (N = 517), an endangered cyprinid. Groups of 18-22 Cape Fear shiners were exposed to DC, 120-Hz pulsed DC (PDC), or 60-Hz PDC at voltage gradients of 1.1, 1.9, or 2.7 V/cm for 3 s. Mortality occurred only among fish exposed to 120-Hz PDC (25%) and DC (38%) applied at 2.7 V/cm. Because no mortality occurred in Cape Fear shiners exposed to 60-Hz PDC, this waveform was selected for further study of electroshock duration (3, 6, 12, 24, or 48 s) and voltage gradient (0.9, 1.6, or 2.3 V/cm). Most fish electroshocked in the experiments were immobilized (ceased swimming motion). No physical injury was detected by necropsy or radiography in any fish. Electroshock-induced mortality of Cape Fear shiners showed a strong multivariable relationship to voltage gradient, electroshock duration, and fish length. Fish subjected to 60-Hz PDC at 0.9 or 1.6 V/cm for 6 s experienced low mortality (<10%). Our results demonstrate that Cape Fear shiners can be immobilized by 60-Hz PDC electroshock without injury or significant risk of mortality. We propose that electrofishing may be safely used to sample similar small cyprinids, imperiled or otherwise, when electrofishers select an appropriate waveform (DC pulsed at 60-Hz or less) and use it judiciously (minimal exposure at, or below, the immobilization threshold).

Cape Cod National Seashore : satellite maintenance facility feasibility study

DOT National Transportation Integrated Search

2010-09-30

This report analyzes the benefits and costs of a potential satellite vehicle maintenance facility on the outer portion of Cape Cod. A satellite facility had been proposed as a means of servicing the local transit vehicles that bring visitors to Cape ...

Potential adverse health effects of persistent organic pollutants on sea turtles: evidences from a cross-sectional study on Cape Verde loggerhead sea turtles.

PubMed

Camacho, María; Luzardo, Octavio P; Boada, Luis D; López Jurado, Luis F; Medina, María; Zumbado, Manuel; Orós, Jorge

2013-08-01

The Cape Verde nesting population of loggerhead sea turtles (Caretta caretta) is the third largest population of this species in the world. For conservation purposes, it is essential to determine how these reptiles respond to different types of anthropogenic contaminants. We evaluated the presence of organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs) in the plasma of adult nesting loggerheads from Boa Vista Island, Cape Verde, and studied the effects of the contaminants on the health status of the turtles using hematological and biochemical parameters. All turtles had detectable levels of non-dioxin like PCBs, whereas dioxin-like congeners (DL-PCBs) were detected in only 30% of the turtles. Packed cell volume decreased with higher concentrations of PCBs, which suggests that PCB exposure could result in anemia in sea turtles. In addition, a negative association between some OCPs and white blood cells (WBC) and thrombocyte estimate was noted. The DDT-metabolite, p,p'-DDE was negatively correlated with the Na/K ratio and, additionally, a number of correlations between certain PAHs and electrolyte balances were found, which suggest that exposure to these environmental contaminants could affect the kidneys and salt glands in sea turtles. Additionally, several correlations were observed between these environmental pollutants (OCPs and PAHs) and enzyme activity (GGT, ALT, ALP and amylase) and serum protein levels, pointing to the possibility that these contaminants could induce adverse metabolic effects in sea turtles. Our results indicate that anthropogenic pollutants are present in the Cape Verde loggerhead turtle nesting population and could exert negative effects on several health parameters. Because of the importance of this loggerhead nesting population, protective regulations at national and international levels as well as international action are necessary for assuring the conservation of this population. Copyright © 2013 Elsevier B.V. All rights reserved.

Cross-cultural validation of the Children's Assessment of Participation and Enjoyment (CAPE) in Spain.

PubMed

Longo, E; Badia, M; Orgaz, B; Verdugo, M A

2014-03-01

Despite growing interest in the topic of participation, the construct has not yet been assessed in children and adolescents with and without cerebral palsy (CP) in Spain. As there are no available instruments to measure participation in leisure activities which have been adapted in this country, the goal of this study was to validate a Spanish version of the Children's Assessment of Participation and Enjoyment (CAPE). The sample comprised 199 children and adolescents with CP and 199 without CP, between 8 and 18 years of age, from seven regions in Spain. The adaptation of the original version of CAPE was carried out through translation and backward translation, and the validity of the instrument was analysed. Construct validity was assessed through the correlation of the diverse CAPE domains and the quality of life domains (KIDSCREEN questionnaire). Discriminant validity was established by comparing children and adolescents with CP and typically developing children and adolescents. For test-retest reliability, the children and adolescents with and without CP completed the CAPE questionnaire twice within 4 weeks. The correlations found between the CAPE domains and the quality of life domains show that the CAPE presents construct validity. The CAPE discriminated children and adolescents with CP from those without any disability in the results of participation. According to most CAPE domains, typically developing children and adolescents engage in a greater number of activities than children and adolescents with CP. Test-retest reliability for the Spanish version of CAPE was adequate. The study provides a valid instrument to assess the participation of children and adolescents with and without CP who live in Spain. © 2012 John Wiley & Sons Ltd.

Psychometric Properties of “Community Assessment of Psychic Experiences”: Review and Meta-analyses

PubMed Central

Mark, Winifred; Toulopoulou, Timothea

2016-01-01

The Community Assessment of Psychic Experiences (CAPE) has been used extensively as a measurement for psychosis proneness in clinical and research settings. However, no prior review and meta-analysis have comprehensively examined psychometric properties (reliability and validity) of CAPE scores across different studies. To study CAPE’s internal reliability—ie, how well scale items correlate with one another—111 studies were reviewed. Of these, 18 reported unique internal reliability coefficients using data at hand, which were aggregated in a meta-analysis. Furthermore, to confirm the number and nature of factors tapped by CAPE, 17 factor analytic studies were reviewed and subjected to meta-analysis in cases of discrepancy. Results suggested that CAPE scores were psychometrically reliable—ie, scores obtained could be attributed to true score variance. Our review of factor analytic studies supported a 3-factor model for CAPE consisting of “Positive”, “Negative”, and “Depressive” subscales; and a tripartite structure for the Negative dimension consisting of “Social withdrawal”, “Affective flattening”, and “Avolition” subdimensions. Meta-analysis of factor analytic studies of the Positive dimension revealed a tridimensional structure consisting of “Bizarre experiences”, “Delusional ideations”, and “Perceptual anomalies”. Information on reliability and validity of CAPE scores is important for ensuring accurate measurement of the psychosis proneness phenotype, which in turn facilitates early detection and intervention for psychotic disorders. Apart from enhancing the understanding of psychometric properties of CAPE scores, our review revealed questionable reporting practices possibly reflecting insufficient understanding regarding the significance of psychometric properties. We recommend increased focus on psychometrics in psychology programmes and clinical journals. PMID:26150674

Cervical cancer prevention in El Salvador (CAPE)-An HPV testing-based demonstration project: Changing the secondary prevention paradigm in a lower middle-income country.

PubMed

Maza, Mauricio; Alfaro, Karla; Garai, Jillian; Velado, Mario Morales; Gage, Julia C; Castle, Philip E; Felix, Juan; Luciani, Silvana; Campos, Nicole; Kim, Jane; Masch, Rachel; Cremer, Miriam

2017-05-01

•CareHPV tests were used to compare screen-and-treat and colposcopy management.•Screen-and-treat strategy with HPV testing was found to be very cost-effective.•CAPE has screened > 25,000 women in the Paracentral region.•Over 70% of screen-positive women received recommended treatment within six months.•CAPE is an example of public-private partnership resulting in paradigm change.

Quaternary geophysical framework of the northeastern North Carolina coastal system

USGS Publications Warehouse

Thieler, E.R.; Foster, D.S.; Mallinson, D.M.; Himmelstoss, E.A.; McNinch, J.E.; List, J.H.; Hammar-Klose, E.S.

2013-01-01

The northeastern North Carolina coastal system, from False Cape, Virginia, to Cape Lookout, North Carolina, has been studied by a cooperative research program that mapped the Quaternary geologic framework of the estuaries, barrier islands, and inner continental shelf. This information provides a basis to understand the linkage between geologic framework, physical processes, and coastal evolution at time scales from storm events to millennia. The study area attracts significant tourism to its parks and beaches, contains a number of coastal communities, and supports a local fishing industry, all of which are impacted by coastal change. Knowledge derived from this research program can be used to mitigate hazards and facilitate effective management of this dynamic coastal system.

A Cretaceous origin for fire adaptations in the Cape flora.

PubMed

He, Tianhua; Lamont, Byron B; Manning, John

2016-10-05

Fire has had a profound effect on the evolution of worldwide biotas. The Cape Floristic Region is one of the world's most species-rich regions, yet it is highly prone to recurrent fires and fire-adapted species contribute strongly to the overall flora. It is hypothesized that the current fire regimes in the Cape could be as old as 6-8 million years (My), while indirect evidence indicates that the onset of fire could have reached 18 million years ago (Ma). Here, we trace the origin of fire-dependent traits in two monocot families that are significant elements in the fire-prone Cape flora. Our analysis shows that fire-stimulated flowering originated in the Cape Haemodoraceae 81 Ma, while fire-stimulated germination arose in the African Restionaceae at least 70 Ma, implying that wildfires have been a significant force in the evolution of the Cape flora at least 60 My earlier than previous estimates. Our results provide strong evidence for the presence of fire adaptations in the Cape from the Cretaceous, leading to the extraordinary persistence of a fire-adapted flora in this biodiversity hotspot, and giving support to the hypothesis that Cretaceous fire was a global phenomenon that shaped the evolution of terrestrial floras.

Cape Lookout National Seashore passenger ferry transportation feasibility study

DOT National Transportation Integrated Search

2010-09-01

The Cape Lookout National Seashore Passenger Ferry Transportation Feasibility Study is a technical study documenting the capital investment and operational considerations associated with consolidation of passenger ferry service from Harkers Island an...

Gender Dimension in the Development of Effective Teaching Skills among University of Cape Coast (UCC) Distance Education Students

ERIC Educational Resources Information Center

Ahiatrogah, Paul Dela

2017-01-01

The study examined gender dimension in the development of effective teaching skills among distance education (DE) students. The conceptual framework for the study is gender mainstreaming which centres on pluralistic approach to diversity issues among both men and women. A longitudinal developmental research design was used for the study. A sample…

Early Rockets

NASA Image and Video Library

1990-07-25

An Atlas Centaur rocket (AC-S9) was launched from Cape Canaveral Air Force Station complex 36B carrying into orbit the Combined Release and Radiation Effects Satellite (CRRES) spacecraft. CRRES was a joint NASA/Air Force mission to study the effects of chemical release on the Earth’s atmosphere and magnetosphere.

Geostationary Coastal and Air Pollution Events (GEO-CAPE) Sensitivity Analysis Experiment

NASA Technical Reports Server (NTRS)

Lee, Meemong; Bowman, Kevin

2014-01-01

Geostationary Coastal and Air pollution Events (GEO-CAPE) is a NASA decadal survey mission to be designed to provide surface reflectance at high spectral, spatial, and temporal resolutions from a geostationary orbit necessary for studying regional-scale air quality issues and their impact on global atmospheric composition processes. GEO-CAPE's Atmospheric Science Questions explore the influence of both gases and particles on air quality, atmospheric composition, and climate. The objective of the GEO-CAPE Observing System Simulation Experiment (OSSE) is to analyze the sensitivity of ozone to the global and regional NOx emissions and improve the science impact of GEO-CAPE with respect to the global air quality. The GEO-CAPE OSSE team at Jet propulsion Laboratory has developed a comprehensive OSSE framework that can perform adjoint-sensitivity analysis for a wide range of observation scenarios and measurement qualities. This report discusses the OSSE framework and presents the sensitivity analysis results obtained from the GEO-CAPE OSSE framework for seven observation scenarios and three instrument systems.

Simulated precipitation diurnal cycles over East Asia using different CAPE-based convective closure schemes in WRF model

NASA Astrophysics Data System (ADS)

Yang, Ben; Zhou, Yang; Zhang, Yaocun; Huang, Anning; Qian, Yun; Zhang, Lujun

2018-03-01

Closure assumption in convection parameterization is critical for reasonably modeling the precipitation diurnal variation in climate models. This study evaluates the precipitation diurnal cycles over East Asia during the summer of 2008 simulated with three convective available potential energy (CAPE) based closure assumptions, i.e. CAPE-relaxing (CR), quasi-equilibrium (QE), and free-troposphere QE (FTQE) and investigates the impacts of planetary boundary layer (PBL) mixing, advection, and radiation on the simulation by using the weather research and forecasting model. The sensitivity of precipitation diurnal cycle to PBL vertical resolution is also examined. Results show that the precipitation diurnal cycles simulated with different closures all exhibit large biases over land and the simulation with FTQE closure agrees best with observation. In the simulation with QE closure, the intensified PBL mixing after sunrise is responsible for the late-morning peak of convective precipitation, while in the simulation with FTQE closure, convective precipitation is mainly controlled by advection cooling. The relative contributions of different processes to precipitation formation are functions of rainfall intensity. In the simulation with CR closure, the dynamical equilibrium in the free troposphere still can be reached, implying the complex cause-effect relationship between atmospheric motion and convection. For simulations in which total CAPE is consumed for the closures, daytime precipitation decreases with increased PBL resolution because thinner model layer produces lower convection starting layer, leading to stronger downdraft cooling and CAPE consumption. The sensitivity of the diurnal peak time of precipitation to closure assumption can also be modulated by changes in PBL vertical resolution. The results of this study help us better understand the impacts of various processes on the precipitation diurnal cycle simulation.

The "Cape Times"'s Portrayal of School Violence

ERIC Educational Resources Information Center

de Wet, Corene

2016-01-01

This study explores the "Cape Times"'s portrayal of school violence in the Western Cape (WC), South Africa, reporting on findings from a qualitative content analysis of 41 news articles retrieved from the SA Media database. The findings shed light on the victims and their victimisation, the perpetrators, as well as the context of the…

Everolimus plus exemestane versus bevacizumab-based chemotherapy for second-line treatment of hormone receptor-positive metastatic breast cancer in Greece: An economic evaluation study.

PubMed

Kourlaba, Georgia; Rapti, Vasiliki; Alexopoulos, Athanasios; Relakis, John; Koumakis, Georgios; Chatzikou, Magdalini; Maniadakis, Nikos; Georgoulias, Vassilis

2015-08-05

The objective of our study was to conduct a cost-effectiveness (CE) study of combined everolimus (EVE) and exemestane (EXE) versus the common clinical practice in Greece for the treatment of postmenopausal women with HR+/HER2- advanced breast cancer (BC) progressing on nonsteroidal aromatase inhibitors (NSAI). The combinations of bevacizumab (BEV) plus paclitaxel (PACL) and BEV plus capecitabine (CAPE) were selected as comparators. A Markov model, consisting of three health states, was used to describe disease progression and evaluate the CE of the comparators from a third-party payer perspective over a lifetime horizon. Efficacy and safety data as well as utility values considered in the model were extracted from the relevant randomized Phase III clinical trials and other published studies. Direct medical costs referring to the year 2014 were incorporated in the model. A probabilistic sensitivity analysis was conducted to account for uncertainty and variation in the parameters of the model. Primary outcomes were patient survival (life-years), quality-adjusted life years (QALYs), total direct costs and incremental cost-effectiveness ratios (ICER). The discounted quality-adjusted survival of patients treated with EVE plus EXE was greater by 0.035 and 0.004 QALYs, compared to BEV plus PACL and BEV plus CAPE, respectively. EVE plus EXE was the least costly treatment in terms of drug acquisition, administration, and concomitant medications. The total lifetime cost per patient was estimated at €55,022, €67,980, and €62,822 for EVE plus EXE, BEV plus PACL, and BEV plus CAPE, respectively. The probabilistic analysis confirmed the deterministic results. Our results suggest that EVE plus EXE may be a dominant alternative relative to BEV plus PACL and BEV plus CAPE for the treatment of HR+/HER2- advanced BC patients failing initial therapy with NSAIs.

Strategies GeoCape Intelligent Observation Studies @ GSFC

NASA Technical Reports Server (NTRS)

Cappelaere, Pat; Frye, Stu; Moe, Karen; Mandl, Dan; LeMoigne, Jacqueline; Flatley, Tom; Geist, Alessandro

2015-01-01

This presentation provides information a summary of the tradeoff studies conducted for GeoCape by the GSFC team in terms of how to optimize GeoCape observation efficiency. Tradeoffs include total ground scheduling with simple priorities, ground scheduling with cloud forecast, ground scheduling with sub-area forecast, onboard scheduling with onboard cloud detection and smart onboard scheduling and onboard image processing. The tradeoffs considered optimzing cost, downlink bandwidth and total number of images acquired.

Assessment and forecasting of lightning potential and its effect on launch operations at Cape Canaveral Air Force Station and John F. Kennedy Space Center

NASA Technical Reports Server (NTRS)

Weems, J.; Wyse, N.; Madura, J.; Secrist, M.; Pinder, C.

1991-01-01

Lightning plays a pivotal role in the operation decision process for space and ballistic launches at Cape Canaveral Air Force Station and Kennedy Space Center. Lightning forecasts are the responsibility of Detachment 11, 4th Weather Wing's Cape Canaveral Forecast Facility. These forecasts are important to daily ground processing as well as launch countdown decisions. The methodology and equipment used to forecast lightning are discussed. Impact on a recent mission is summarized.

Reliability of the German version of the Children's Assessment of Participation and Enjoyment (CAPE) and Preferences for Activities of Children (PAC).

PubMed

Fink, A; Gebhard, B; Erdwiens, S; Haddenhorst, L; Nowak, S

2016-09-01

The introduction of the International Classification of Functioning, Disabilities and Health of the World Health Organization in 2001 made social participation a major rehabilitation outcome and the ultimate goal of rehabilitation services. There is no available instrument to measure the youth participation in leisure activities apart from asking the youth themselves. The goal of this study was to present a German version of the Children's Assessment of Participation and Enjoyment and Preferences for Activities of Children (CAPE/PAC). The CAPE/PAC questionnaire was translated into German, a cultural adaptation process was designed and a reliability study was conducted. One hundred and fifty-two youths with and without disabilities, with a mean age of 15.2 years (standard deviation 1.7), participated in the study. The participants completed CAPE and PAC twice within 4 weeks. Reliability was examined by intraclass correlation coefficients, standard error of measurement, smallest detectable change and Cronbach's alpha. The absolute values of participation differ between the typically developed youth group and those with impairments; the reliability of the CAPE/PAC is comparable in both groups. Intraclass correlation coefficients ranged from 0.43 to 0.74 for the CAPE and from 0.71 to 0.83 for the PAC in all participants. The alpha values for internal consistency ranged from 0.42 to 0.82 for the CAPE and from 0.65 to 0.92 for the PAC. The German version of the PAC showed satisfactory reliability; however, reliability was not satisfactory for all scores of the CAPE, but comparable with versions in other languages. The need for newly developed participation measurements requires further discussion. © 2016 John Wiley & Sons Ltd.

Caffeic Acid Phenethyl Ester (Propolis Extract) Ameliorates Insulin Resistance by Inhibiting JNK and NF-κB Inflammatory Pathways in Diabetic Mice and HepG2 Cell Models.

PubMed

Nie, Jiarui; Chang, Yaning; Li, Yujia; Zhou, Yingjun; Qin, Jiawen; Sun, Zhen; Li, Haibin

2017-10-18

Caffeic acid phenethyl ester (CAPE), extracted from propolis, was evaluated for the ameliorative effects on insulin resistance and the mechanisms were identified, using non-insulin-dependent diabetes mellitus (NIDDM) model mice and insulin resistance (IR) model cells. After 5 weeks of CAPE supplementation, insulin sensitivity, hyperlipidemia, and peroxisome proliferator-activated receptor-α (PPAR-α) levels were improved in mice. Proinflammatory cytokines in serum and the expressions of tumor necrosis factor-alpha (TNF-α) mRNA in tissues were markedly downregulated from CAPE-treated mice. In vitro, CAPE supplement significantly improved glucose consumption, glucose uptake, glycogen content, and oxidative stress and decreased expression of glucose-6-phosphatase (G6Pase) mRNA in cells. Both in vivo and in vitro, CAPE enhanced p-Akt (Ser473) and p-insulin receptor substrate (IRS)-1 (Tyr612), but inhibited p-JNK (Thr183/Tyr185), p-NF-κB p65 (Ser536), and nuclear translocation of p-NF-κB p65 (Ser536). In summary, CAPE can ameliorate insulin resistance through modulation of JNK and NF-κB signaling pathway in mice and HepG2 cells.

A study of psychrophilic organisms isolated from the manufacture and assembly areas of spacecraft to be used in the Viking mission

NASA Technical Reports Server (NTRS)

Foster, T. L.

1974-01-01

The effect of storage of dry heat treated Teflon ribbons under nitrogen gas followed by high vacuum on the recovery of hardy organisms from the ribbons was studied. A similar experiment was performed on spore crops of hardy organisms recovered previously from Cape Canaveral. Hardy organisms have been inoculated onto slides and subjected to an artificial Martian environment in an attempt to demonstrate their growth in this environment. Additional experiments using the artificial Martian environment include response of soil samples from the VAB with both constant temperature and freeze-thaw cycles. These experiments were performed with dried soil and soil containing added water. Other investigations included the effect of heatshock on soil samples, psychrophilic counts of new soil samples from the manufacture area of the Viking spacecraft, effect of pour plate versus spread plate on psychrophilic counts, and preparation of spore crops of hardy organisms from Cape Canaveral.

Investigating Coastal Processes Responsible for Large-Scale Shoreline Responses to Human Shoreline Stabilization

NASA Astrophysics Data System (ADS)

Slott, J. M.; Murray, A. B.; Ashton, A. D.

2006-12-01

Human shoreline stabilization practices, such as beach nourishment (i.e. placing sand on an eroding beach), have become more prevalent as erosion threatens coastal communities. On sandy shorelines, recent experiments with a numerical model of shoreline change (Slott, et al., in press) indicate that moderate shifts in storminess patterns, one possible outcome of global warming, may accelerate the rate at which shorelines erode or accrete, by altering the angular distribution of approaching waves (the `wave climate'). Accelerated erosion would undoubtedly place greater demands on stabilization. Scientists and coastal engineers have typically only considered the site-specific consequences of shoreline stabilization; here we explore the coastal processes responsible for large-scale (10's kms) and long-term (decades) effects using a numerical model developed by Ashton, et al. (2001). In this numerical model, waves breaking at oblique angles drive a flux of sediment along the shoreline, where gradients in this flux can shape the coastline into surprisingly complex forms (e.g. cuspate-capes found on the Carolina coast). Wave "shadowing" plays a major role in shoreline evolution, whereby coastline features may block incoming waves from reaching distant parts. In this work, we include beach nourishment in the Ashton, et al. (2001) model. Using a cuspate-cape shoreline as our initial model condition, we conducted pairs of experiments and varied the wave-climate forcing across each pair, each representing different storminess scenarios. Here we report on one scenario featuring increased extra-tropical storm influence. For each experiment-pair we ran a control experiment with no shoreline stabilization and a second where a beach nourishment project stabilized a cape tip. By comparing the results of these two parallel runs, we isolate the tendency of the shoreline to migrate landward or seaward along the domain due solely to beach nourishment. Significant effects from beach nourishment reached several tens of kilometers away from the nourishment project. The magnitude of these effects rivaled the erosion we expect from sea-level rise alone over the coming century. Furthermore, the nature of the effects were unexpected: where we expect beach nourishment sand to spread laterally in the direction of net alongshore sediment transport (e.g. to the right looking off-shore), coastline segments to the right of the cape should tend to migrate seaward, while segments to the left of the cape might naively be expected to feel little effects. We observed, however, that shoreline segments to the left (right) of the stabilized cape tip tended to migrate seaward (landward). Two statistics we collected for each model run--the extent of wave shadowing and the net flux of sediment at each alongshore position--helped explain the surprising behavior. By pinning the location of the cape tip, beach nourishment altered the way in which the cape shadowed adjacent coastlines. The stabilized cape-tip shadowed segments to the left more often, increasing the influence from left-approaching waves. These shoreline segments shifted seaward, relative to the non-nourishment case, through a convergence in alongshore sediment transport from increased transport from the left, rather than from laterally-spreading beach nourishment sand. The stabilized cape-tip shadowed segments to the right less often, increasing the influence of left-approaching waves. These segments shifted landward through a divergence in alongshore sediment transport from increased transport to the right.

Diurnal Variability of the inner-shelf circulation in the lee of a cape under upwelling conditions

NASA Astrophysics Data System (ADS)

Lamas, Luisa; Peliz, Álvaro; Marchesiello, Patrick

2013-04-01

The circulation over the inner-shelf is a key component of shelf dynamics and an important mechanism for cross-shore exchange on most shelves. Yet our understanding of the cross-shore circulation and how it depends on different forcing conditions, bathymetry and stratification remains poor due in part to sparse observations and the difficulty of resolving spatial and temporal scales within the inner-shelf. Most studies of cross-shore transport on the inner-shelf consider only a 2D circulation, due to coastal upwelling or downwelling and assume along-shore uniformity. However, divergence in the along-shore and cross-shore flows may occur with the presence of complex coastline topography or subtle bathymetric features, and can drive substantial horizontal cross-shore exchange, with same order of magnitude as coastal upwelling and downwelling. A recent study using observational data collected near cape Sines, Portugal, showed that not only wind, waves and tides are important forcing mechanisms of the inner-shelf circulation, but also that the along-shore pressure gradient plays a major role on driving cross-shore exchange. A modeling study was conducted in order to study the complexity of the inner-shelf dynamics, in the presence of a cape. A simplified configuration was used in order to isolate the effects of individual processes: wind, heat fluxes, tides and waves. The preliminary results of the effects of these processes on the inner-shelf circulation will be presented.

The Prevalence of Fetal Alcohol Syndrome and Its Impact on a Child's Classroom Performance: A Case Study of a Rural South African School.

PubMed

Lubbe, Melissa; van Walbeek, Corné; Vellios, Nicole

2017-08-09

Alcohol consumption is high among farm labourers in the Western and Northern Cape of South Africa. Excessive alcohol consumption during pregnancy is common, resulting in a high prevalence of Fetal Alcohol Syndrome (FAS) among children. FAS causes intellectual and behavioural problems, which create considerable obstacles to a child's education. The aim of this study is to provide a prevalence estimate of FAS in a rural school and to examine the effects of FAS on learners' educational outcomes. The study was conducted at a farm school near Clanwilliam in the Western Cape of South Africa. The sample comprises 166 learners from Grades 1 to 4. Educational outcomes include class scores (Afrikaans Home Language and Mathematics), reading ability, and classroom behaviour. A physician diagnosed FAS using a three-stage process. We find FAS prevalence of 127 per 1000 (12.7%). Children with FAS score significantly lower (at the 10% level) for home language and behaviour than children who do not have FAS. Large-scale interventions in rural areas of the Western and Northern Cape that specifically target females of child-bearing age, as well aschildren with FAS, are necessary.

The Prevalence of Fetal Alcohol Syndrome and Its Impact on a Child’s Classroom Performance: A Case Study of a Rural South African School

PubMed Central

Lubbe, Melissa; van Walbeek, Corné

2017-01-01

Alcohol consumption is high among farm labourers in the Western and Northern Cape of South Africa. Excessive alcohol consumption during pregnancy is common, resulting in a high prevalence of Fetal Alcohol Syndrome (FAS) among children. FAS causes intellectual and behavioural problems, which create considerable obstacles to a child’s education. The aim of this study is to provide a prevalence estimate of FAS in a rural school and to examine the effects of FAS on learners’ educational outcomes. The study was conducted at a farm school near Clanwilliam in the Western Cape of South Africa. The sample comprises 166 learners from Grades 1 to 4. Educational outcomes include class scores (Afrikaans home language and mathematics), reading ability, and classroom behaviour. A physician diagnosed FAS using a three-stage process. We find FAS prevalence of 127 per 1000 (12.7%). Children with FAS score significantly lower (at the 10% level) for home language and behaviour than children who do not have FAS. Large-scale interventions in rural areas of the Western and Northern Cape that specifically target females of child-bearing age, as well as children with FAS, are necessary. PMID:28792446

76 FR 38302 - Safety Zone; Cape Charles Fireworks, Cape Charles Harbor, Cape Charles, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-30

... the Town of Cape Charles will sponsor a fireworks display on the shoreline of the navigable waters of...-AA00 Safety Zone; Cape Charles Fireworks, Cape Charles Harbor, Cape Charles, VA AGENCY: Coast Guard... navigable waters of Cape Charles City Harbor in Cape Charles, VA in support of the Fourth of July Fireworks...

Ethanol extract of propolis and its constituent caffeic acid phenethyl ester inhibit breast cancer cells proliferation in inflammatory microenvironment by inhibiting TLR4 signal pathway and inducing apoptosis and autophagy.

PubMed

Chang, Huasong; Wang, Yuehua; Yin, Xusheng; Liu, Xinying; Xuan, Hongzhuan

2017-09-26

Propolis and its major constituent - caffeic acid phenethyl ester (CAPE) have good abilities on antitumor and anti-inflammation. However, little is known about the actions of propolis and CAPE on tumor in inflammatory microenvironment, and inflammatory responses play decisive roles at different stages of tumor development. To understand the effects and mechanisms of ethanol-extracted Chinese propolis (EECP) and its major constituent - CAPE in inflammation-stimulated tumor, we investigated their effects on Toll-like receptor 4 (TLR4) signaling pathway which plays a crucial role in breast cancer MDA-MB-231 cell line. 80% confluent breast cancer MDA-MB-231 cells were stimulated with 1 μg/mL lipopolysaccaride (LPS). Then the cells were divided for treatment by CAPE (25 μg/mL) and EECP (25, 50 and 100 μg/mL), respectively. Cell viability, nitric oxide (NO) production and cell migration were measured by sulforhodamine B assay, chemical method and scratch assay. The levels of TLR4, MyD88, IRAK4, TRIF, caspase 3, PARP, LC3B and p62 were investigated through western blotting. The expression of TLR4, LC3B and nuclear factor-κB p65 (NF-κB p65) were tested by immunofluorescence microscopy assay. Treatment of different concentrations of EECP (25, 50 and 100 μg/mL) and CAPE (25 μg/mL) significantly inhibited LPS-stimulated MDA-MB-231 cell line proliferation, migration and NO production. Furthermore, EECP and CAPE activated caspase3 and PARP to induce cell apoptosis, and also upregulated LC3-II and decreased p62 level to induce autophagy during the process. TLR4 signaling pathway molecules such as TLR4, MyD88, IRAK4, TRIF and NF-κB p65 were all down-regulated after EECP and CAPE treatment in LPS-stimulated MDA-MB-231 cells. These findings indicated that EECP and its major constituent - CAPE inhibited breast cancer MDA-MB-231 cells proliferation in inflammatory microenvironment through activating apoptosis, autophagy and inhibiting TLR4 signaling pathway. EECP and CAPE may hold promising prospects in treating inflammation-induced tumor.

Burnout among rural hospital doctors in the Western Cape: Comparison with previous South African studies.

PubMed

Liebenberg, Andrew R; Coetzee Jnr, Johan F; Conradie, Hofmeyr H; Coetzee, Johan F

2018-05-24

Burnout among doctors negatively affects health systems and, ultimately,patient care. To determine the prevalence of burnout among doctors working in the district health system in the Overberg and Cape Winelands districts of the Western Cape Province and to compare the findings with those of previous South African studies. Rural district hospitals. During 2013, a validated questionnaire (Maslach Burnout Inventory) was sent to 42 doctors working in the district health system within the referral area of the Worcester Hospital, consisting of the Overberg health district and the eastern half of the Cape Winelands. Response rate was 85.7%. Clinically significant burnout was found among 81% of respondents. High levels of burnout on all three subscales were present in 31% of participants.Burnout rates were similar to those of a previous study conducted among doctors working in the Cape Town Metropolitan Municipality primary health care facilities. Scores for emotional exhaustion (EE) and depersonalisation (DP) were greater than those of a national survey;however, the score for personal accomplishment (PA) was greater. EE and PA scores weresimilar to that of a study of junior doctors working in the Red Cross Children's Hospital;however, EE was smaller. This study demonstrates high burnout rates among doctors working at district level hospitals, similar to the prevalence thereof in the Cape Town Metropolitan primary health care facilities. Health services planning should include strategies to address and prevent burnout of which adequate staffing and improved work environment are of prime importance.

Parental Investment, Club Membership, and Youth Sexual Risk Behavior in Cape Town

PubMed Central

Camlin, Carol S.; Snow, Rachel C.

2010-01-01

This study examines whether parental investment and membership in social clubs are associated with safer sexual behaviors among South African youth. Participants comprised 4,800 randomly selected adolescents age 14 to 22 living in the Cape Town area in 2002. Logistic regression was used to examine associations between measures of parental investment and associational membership with reported condom use at first and most recent sexual intercourse, net of effects of HIV knowledge, age, education, population group, parental coresidence, and household income. Interaction terms were used to examine gender differences in associations between risk behavior and parental investment and between risk behavior and group membership. Participation in clubs and community groups is associated with safer behaviors. A mother’s financial support (for clothing, school fees and uniforms, and pocket money) is negatively associated with condom use, particularly among young women, suggesting that material need impels vulnerability to higher risk behaviors. Social resources in households and communities mediate HIV risk behaviors among youth in Cape Town. PMID:18375613

77 FR 29929 - Safety Zone; Town of Cape Charles Fireworks, Cape Charles Harbor, Cape Charles, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-21

... section of this notice. Basis and Purpose On July 4, 2012 the Town of Cape Charles will sponsor a...-AA00 Safety Zone; Town of Cape Charles Fireworks, Cape Charles Harbor, Cape Charles, VA AGENCY: Coast... temporary safety zone on the waters of Cape Charles City Harbor in Cape Charles, VA in support of the Fourth...

The Challenges of Using the WebCAPE Placement Exam in an Advanced Spanish Grammar Class

ERIC Educational Resources Information Center

Turner, Robert L., III

2017-01-01

This study attempts to ascertain if the WebCAPE placement exam can be used to measure improvement in an upper division grammar course. The WebCAPE online placement exam is a widely used instrument designed to help university language programs place students into the basic language course best corresponding to their proficiency level. This is done…

The effect of season and latitude on in vitro vitamin D formation by sunlight in South Africa.

PubMed

Pettifor, J M; Moodley, G P; Hough, F S; Koch, H; Chen, T; Lu, Z; Holick, M F

1996-10-01

To assess the effect of season and latitude on the in vitro formation of previtamin D3 and vitamin D3 from 7-dehydrocholesterol (7-DHC) by sunlight in two cities in South Africa, Cape Town and Johannesburg. An in vitro study utilising vials containing 7-DHC, which were exposed to sunlight for a period of 1 hour between 8:00 and 17:00 on 1 day a month for a year. Previtamin D3 and vitamin D3 were separated from 7-DHC by high-performance liquid chromatography, and the amounts formed were calculated with the use of external standards. A marked seasonal variation in vitamin D3 production was noted in Cape Town, with very little being formed during the winter months of April through September. In Johannesburg, in vitro formation changed little throughout the year, and was similar to that found in Cape Town during the summer. During sunlit hours, vitamin D3 production was maximal at midday and small quantities were still being formed between 8:00 and 9:00, and between 16:00 and 17:00 during the summer. During winter in Cape Town, peak formation at midday was less than one-third of that in Johannesburg, and negligible amounts were formed before 10:00 and after 15:00. The previously documented seasonal variation in serum 25-hydroxyvitamin D recorded in patients in Johannesburg is probably a consequence of the increased clothing worn and the decreased time spent out of doors during winter, rather than decreased ultraviolet radiation reaching the earth. The limited in vitro formation of vitamin D3 during winter in Cape Town may have clinical implications insofar as the management of metabolic bone diseases like rickets and osteoporosis is concerned. Breast-fed infants resident in the area are likely to suffer from vitamin D deficiency rickets unless vitamin D supplements are provided, or the mothers are encouraged to take their children out of doors.

Developing qualitative ecosystem service relationships with the Driver-Pressure-State-Impact-Response framework: A case study on Cape Cod, Massachusetts

EPA Science Inventory

Understanding the effects of environmental management strategies on society and the environment is critical for evaluating their effectiveness but is often impeded by limited data availability. In this article, we present a method that can help scientists to support environmental...

Effects of laughing gull and shorebird predation on the intertidal fauna at Cape May, New Jersey

NASA Astrophysics Data System (ADS)

Botton, M. L.

1984-02-01

The intertidal flats of the Cape May, New Jersey shore of Delaware Bay are populated by large numbers of laughing gulls and migrating shorebirds during the spring and early summer. Exclusion of birds from a shallow slough and a sand bar had only minor effects on the infaunal benthic invertebrate assemblage at either site. The Cape May beaches provide a rich source of food in the form of horseshoe crab ( Limulus polyphemus) eggs; foraging on this item may be more profitable than probing the sediment for infauna. Gemma gemma, a small, thick-shelled bivalve, composed over 98% of the benthic infauna at both sites in 1980, and this species may be resistant to predation by certain shorebirds, as suggested by Schneider (1978).

1H-NMR and UPLC-MS metabolomics: Functional tools for exploring chemotypic variation in Sceletium tortuosum from two provinces in South Africa.

PubMed

Zhao, Jianping; Khan, Ikhlas A; Combrinck, Sandra; Sandasi, Maxleene; Chen, Weiyang; Viljoen, Alvaro M

2018-05-17

Sceletium tortuosum (Aizoaceae) is widely recognised for the treatment of stress, anxiety and depression, as well as for obsessive compulsive disorders. A comprehensive intraspecies chemotypic variation study, using samples harvested from two distinct regions of South Africa, was done using both proton nuclear magnetic resonance ( 1 H-NMR) spectroscopy of methanol extracts (N = 145) and ultra performance liquid chromatography-mass spectrometry (UPLC-MS) of acid/base extracts (N = 289). Chemometric analysis of the 1 H-NMR data indicated two main clusters that were region-specific (Northern Cape and Western Cape provinces). Two dimensional (2D) NMR was used to identify analytes that contributed to the clustering as revealed by the S-plot. The sceletium alkaloids, pinitol and two alkylamines, herein reported for the first time from S. tortuosum, were identified as markers that distinguished the two groups. Relative quantification of the marker analytes conducted by qNMR indicated that samples from the Northern Cape generally contained higher concentrations of all the markers than samples from the Western Cape. Quantitative analysis of the four mesembrine alkaloids using a validated UPLC-photo diode array (PDA) detection method confirmed the results of qNMR with regard to the total alkaloid concentrations. Samples from the Northern Cape Province were found to contain, on average, very high total alkaloids, ranging from 4938.0 to 9376.8 mg/kg dry w. Regarding the Western Cape samples, the total yields of the four mesembrine alkaloids were substantially lower (averages 16.4-4143.2 mg/kg). Hierarchical cluster analysis of the UPLC-MS data, based on the alkaloid chemistry, revealed three branches, with one branch comprising samples primarily from the Northern Cape that seemed somewhat chemically conserved, while the other two branches represented mainly samples from the Western Cape. The construction of an orthogonal projections to latent structures-discriminant analysis model and subsequent loadings plot, allowed alkaloid markers to be identified for each cluster. The diverse sceletium alkaloid chemistry of samples from the three clusters may facilitate the recognition of alkaloid profiles, rather than individual compounds, that exert targeted effects on various brain receptors involved in stress, anxiety or depression. Copyright © 2018 Elsevier Ltd. All rights reserved.

76 FR 27970 - Safety Zone; Cape Charles Fireworks, Cape Charles Harbor, Cape Charles, VA.

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-13

... Charles will sponsor a fireworks display on the shoreline of the navigable waters of Cape Charles City...[deg]01'30'' W (NAD 1983). This safety zone will be established in the vicinity of Cape Charles, VA...-AA00 Safety Zone; Cape Charles Fireworks, Cape Charles Harbor, Cape Charles, VA. AGENCY: Coast Guard...

Simulation of the effects of ground-water withdrawals and recharge on ground-water flow in Cape Cod, Martha's Vineyard, and Nantucket Island basins, Massachusetts

USGS Publications Warehouse

Masterson, John P.; Barlow, Paul M.

1994-01-01

The effects of changing patterns of ground-water pumping and aquifer recharge on the surface-water and ground-water hydrologic systems were determined for the Cape Cod, Martha's Vineyard, and Nantucket Island Basins. Three-dimensional, transient, ground-water-flow modelS that simulate both freshwater and saltwater flow were developed for the f1ow cells of Cape Cod which currently have large-capacity public-supply wells. Only the freshwater-flow system was simulated for the Cape Cod flow cells where public-water supply demands are satisfied by small-capacity domestic wells. Two- dimensional, finite-difference, change models were developed for Martha's Vineyard and Nantucket Island to determine the projected drawdowns in response to projected in-season pumping rates for 180 days of no aquifer recharge. Results of the simulations indicate very little change in the position of the freshwater-saltwater interface from predevelopment flow conditions to projected ground-water pumping and recharge rates for Cape Cod in the year 2020. Results of change model simulations for Martha's Vineyard and Nantucket Island indicate that the greatest impact in response to projected in-season ground-water pumping occurs at the pumping centers and the magnitude of the drawdowns are minimal with respect to the total thickness of the aquifers.

Space Radar Image of Cape Cod, Massachusetts

NASA Technical Reports Server (NTRS)

1994-01-01

This spaceborne radar image shows the famous 'hook' of Cape Cod, Massachusetts. The Cape, which juts out into the Atlantic Ocean about 100 kilometers (62 miles) southeast of Boston, actually consists of sandy debris left behind by the great continental ice sheets when they last retreated from southern New England about 20,000 years ago. Today's landscape consists of sandy forests, fields of scrub oak and other bushes and grasses, salt marshes, freshwater ponds, as well as the famous beaches and sand dunes. In this image, thickly forested areas appear green, marshes are dark blue, ponds and sandy areas are black, and developed areas are mostly pink. The dark L-shape in the lower center is the airport runways in Hyannis, the Cape's largest town. The dark X-shape left of the center is Otis Air Force Base. The Cape Cod Canal, above and left of center, connects Buzzards Bay on the left with Cape Cod Bay on the right. The northern tip of the island of Martha's Vineyard is seen in the lower left. The tip of the Cape, in the upper right, includes the community of Provincetown, which appears pink, and the protected National Seashore areas of sand dunes that parallel the Atlantic coast east of Provincetown. Scientists are using radar images like this one to study delicate coastal environments and the effects of human activities on the ecosystem and landscape. This image was acquired by Spaceborne Imaging Radar-C/X-band Synthetic Aperture Radar (SIR-C/X-SAR) onboard the space shuttle Endeavour on April 15, 1994. The image is 81.7 kilometers by 43.1 kilometers (50.7 miles by 26.7 miles) and is centered at 41.8 degrees north latitude, 70.3 degrees west longitude. North is toward the upper right. The colors are assigned to different radar frequencies and polarizations of the radar as follows: red is L-band, horizontally transmitted and received; green is C-band, horizontally transmitted, vertically received; and blue is C-band, horizontally transmitted and received. SIR-C/X-SAR, a joint mission of the German, Italian and United States space agencies, is part of NASA's Mission to Planet Earth program.

Dusk Lighting of Layered Textures in 'Cape Verde'

NASA Technical Reports Server (NTRS)

2008-01-01

Full-shade lighting in the late Martian afternoon helps make details visible in this view of the layered cliff face of the 'Cape Verde' promontory making up part of the rim of Victoria Crater in the Meridiani Planum region of equatorial Mars.

NASA's Mars Exploration Rover Opportunity used its panoramic camera (Pancam) to shoot the dozens of individual images that have been combined into this mosaic. Opportunity was inside Victoria Crater and near the base of the cliff when it took these images on the 1,579th and 1,580th Martian days, or sols, of the mission (July 2 and 3, 2008).

Photographing the promontory from this position in Victoria Crater presented challenges for the rover team. The geometry was such that Cape Verde was between the rover and the sun, which could cause a range of negative effects, from glinting off Pancam's dusty lenses to shadowing on the cliff face. The team's solution was to take the images for this mosaic just after the sun disappeared behind the crater rim, at about 5:30 p.m. local solar time. The atmosphere was still lit, but no direct sunlight was illuminating the wall of Cape Verde.

The result is a high-resolution view of Cape Verde in relatively uniform diffuse sky lighting across the scene.

Pancam used a clear filter for taking the images for this mosaic. Capturing images in low-light situations was one of the main motivations for including the clear filter among the camera's assortment of filters available for use.

The face of Cape Verde is about 6 meters (20 feet) tall. Victoria Crater, at about 800 meters (one-half mile) wide, is the largest and deepest crater that Opportunity has visited. It sits more than 5 kilometers (almost 4 miles) away from Opportunity's Eagle Crater landing site. Researchers sent Opportunity into Victoria Crater to study the rock layers exposed inside. The textures seen in the rock layers of Cape Verde suggest that the exposed layers were originally deposited by wind.

Low Latitude Aeronomy Study in Africa

DTIC Science & Technology

2016-02-09

In our first attempt, we went to Cape Verde Atmospheric Observatory, which is a British and German joint atmospheric research facility. The...facility has reliable power and internet link. The project PI went to Cape Verde and deployed the instrument at the observatory (Figure 3). However...After careful consideration, we decide to take the instrument back to NCAR. Figure 3. The small FPI (left) and Cape Verde Atmospheric

Simulated interaction between freshwater and saltwater and effects of ground-water pumping and sea-level change, lower Cape Cod aquifer system, Massachusetts

USGS Publications Warehouse

Masterson, John P.

2004-01-01

The U.S. Geological Survey, in cooperation with the National Park Service, Massachusetts Executive Office of Environmental Affairs, Cape Cod Commission, and the Towns of Eastham, Provincetown, Truro, and Wellfleet, began an investigation in 2000 to improve the understanding of the hydrogeology of the four freshwater lenses of the Lower Cape Cod aquifer system and to assess the effects of changing ground-water pumping, recharge conditions, and sea level on ground-water flow in Lower Cape Cod, Massachusetts. A numerical flow model was developed with the computer code SEAWAT to assist in the analysis of freshwater and saltwater flow. Model simulations were used to determine water budgets, flow directions, and the position and movement of the freshwater/saltwater interface. Model-calculated water budgets indicate that approximately 68 million gallons per day of freshwater recharge the Lower Cape Cod aquifer system with about 68 percent of this water moving through the aquifer and discharging directly to the coast, 31 percent flowing through the aquifer, discharging to streams, and then reaching the coast as surface-water discharge, and the remaining 1 percent discharging to public-supply wells. The distribution of streamflow varies greatly among flow lenses and streams; in addition, the subsurface geology greatly affects the position and movement of the underlying freshwater/saltwater interface. The depth to the freshwater/saltwater interface varies throughout the study area and is directly proportional to the height of the water table above sea level. Simulated increases in sea level appear to increase water levels and streamflows throughout the Lower Cape Cod aquifer system, and yet decrease the depth to the freshwater/saltwater interface. The resulting change in water levels and in the depth to the freshwater/saltwater interface from sea-level rise varies throughout the aquifer system and is controlled largely by non-tidal freshwater streams. Pumping from large-capacity municipal-supply wells increases the potential for effects on surface-water bodies, which are affected by pumping and wastewater-disposal locations and rates. Pumping wells that are upgradient of surface-water bodies potentially capture water that would otherwise discharge to these surface-water bodies, thereby reducing streamflow and pond levels. Kettle-hole ponds, such as Duck Pond in Wellfleet, that are near the top of a freshwater flow lens, appear to be more susceptible to changing pumping and recharge conditions than kettle-hole ponds closer to the coast or near discharge boundaries, such as the Herring River.

CAPE suppresses migration and invasion of prostate cancer cells via activation of non-canonical Wnt signaling.

PubMed

Tseng, Jen-Chih; Lin, Ching-Yu; Su, Liang-Chen; Fu, Hsiao-Hui; Yang, Shiaw-Der; Chuu, Chih-Pin

2016-06-21

Prostate cancer (PCa) was the fifth most common cancer overall in the world. More than 80% of patients died from PCa developed bone metastases. Caffeic acid phenethyl ester (CAPE) is a main bioactive component of honeybee hive propolis. Transwell and wound healing assays demonstrated that CAPE treatment suppressed the migration and invasion of PC-3 and DU-145 PCa cells. Gelatin zymography and Western blotting indicated that CAPE treatment reduced the abundance and activity of MMP-9 and MMP-2. Analysis using Micro-Western Array (MWA), a high-throughput antibody-based proteomics platform with 264 antibodies detecting signaling proteins involved in important pathways indicated that CAPE treatment induced receptor tyrosine kinase-like orphan receptor 2 (ROR2) in non-canonical Wnt signaling pathway but suppressed abundance of β-catenin, NF-κB activity, PI3K-Akt signaling, and epithelial-mesenchymal transition (EMT). Overexpression or knockdown of ROR2 suppressed or enhanced cell migration of PC-3 cells, respectively. TCF-LEF promoter binding assay revealed that CAPE treatment reduced canonical Wnt signaling. Intraperitoneal injection of CAPE reduced the metastasis of PC-3 xenografts in tail vein injection nude mice model. Immunohistochemical staining demonstrated that CAPE treatment increased abundance of ROR2 and Wnt5a but decreased protein expression of Ki67, Frizzle 4, NF-κB p65, MMP-9, Snail, β-catenin, and phosphorylation of IκBα. Clinical evidences suggested that genes affected by CAPE treatment (CTNNB1, RELA, FZD5, DVL3, MAPK9, SNAl1, ROR2, SMAD4, NFKBIA, DUSP6, and PLCB3) correlate with the aggressiveness of PCa. Our study suggested that CAPE may be a potential therapeutic agent for patients with advanced PCa.

3 CFR 8467 - Proclamation 8467 of December 23, 2009. To Modify Duty-Free Treatment Under the Generalized...

Code of Federal Regulations, 2010 CFR

2010-01-01

... determined that Cape Verde should be removed from the list of least-developed beneficiary countries. 7. In... reflect in the HTS the termination of the designation of Cape Verde as a least-developed beneficiary... Verde” from the list of least-developed beneficiary developing countries, effective with respect to...

Cape Cod National Seashore integrated parking and transit study

DOT National Transportation Integrated Search

2010-12-31

Beach parking adjacent to the ever changing coastline of the Lower/Outer Cape is subject to erosion. In order to maintain access to the beaches without paving over additional NPS land, this study looks at alternative parking locations and the feasibi...

Chemometric characterization of alembic and industrial sugar cane spirits from cape verde and ceará, Brazil.

PubMed

Pereira, Regina F R; Vidal, Carla B; de Lima, Ari C A; Melo, Diego Q; Dantas, Allan N S; Lopes, Gisele S; do Nascimento, Ronaldo F; Gomes, Clerton L; da Silva, Maria Nataniela

2012-01-01

Sugar cane spirits are some of the most popular alcoholic beverages consumed in Cape Verde. The sugar cane spirit industry in Cape Verde is based mainly on archaic practices that operate without supervision and without efficient control of the production process. The objective of this work was to evaluate samples of industrial and alembic sugar cane spirits from Cape Verde and Ceará, Brazil using principal component analysis. Thirty-two samples of spirits were analyzed, twenty from regions of the islands of Cape Verde and twelve from Ceará, Brazil. Of the samples obtained from Ceará, Brazil seven are alembic and five are industrial spirits. The components analyzed in these studies included the following: volatile organic compounds (n-propanol, isobutanol, isoamylic, higher alcohols, alcoholic grade, acetaldehyde, acetic acid, acetate); copper; and sulfates.

Chemometric Characterization of Alembic and Industrial Sugar Cane Spirits from Cape Verde and Ceará, Brazil

PubMed Central

Pereira, Regina F. R.; Vidal, Carla B.; de Lima, Ari C. A.; Melo, Diego Q.; Dantas, Allan N. S.; Lopes, Gisele S.; do Nascimento, Ronaldo F.; Gomes, Clerton L.; da Silva, Maria Nataniela

2012-01-01

Sugar cane spirits are some of the most popular alcoholic beverages consumed in Cape Verde. The sugar cane spirit industry in Cape Verde is based mainly on archaic practices that operate without supervision and without efficient control of the production process. The objective of this work was to evaluate samples of industrial and alembic sugar cane spirits from Cape Verde and Ceará, Brazil using principal component analysis. Thirty-two samples of spirits were analyzed, twenty from regions of the islands of Cape Verde and twelve from Ceará, Brazil. Of the samples obtained from Ceará, Brazil seven are alembic and five are industrial spirits. The components analyzed in these studies included the following: volatile organic compounds (n-propanol, isobutanol, isoamylic, higher alcohols, alcoholic grade, acetaldehyde, acetic acid, acetate); copper; and sulfates. PMID:23227051

33 CFR 165.530 - Safety Zone: Cape Fear and Northeast Cape Fear Rivers, NC.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Northeast Cape Fear Rivers, NC. 165.530 Section 165.530 Navigation and Navigable Waters COAST GUARD... § 165.530 Safety Zone: Cape Fear and Northeast Cape Fear Rivers, NC. (a) Location. The following area is a moving safety zone during the specified conditions: The waters of the Cape Fear and Northeast Cape...

Environmental Education Evaluation at the School: An Example in Sao Nicolau Island, Cape Verde

ERIC Educational Resources Information Center

Graziani, Pietro; Cabral, Daniel; Santana, Nelson

2013-01-01

Monte Gordo Natural Park (MGNP) is part of the Cape Verde (CV) Protected Areas National Network. In order to create an effective Environmental Education (EE) curriculum, it is crucial to first identify the level of environmental knowledge of both teachers and students. In 2007 we implemented a set of four surveys to students and educators and…

Utilizing NASA Earth Observations to investigate habitat suitability of the Cape Vulture in the Western Cape Province of South Africa

NASA Astrophysics Data System (ADS)

Gray, D.; Estes, M. G., Jr.; Griffin, R.; Estes, S. M.

2017-12-01

As the global urban population rapidly increases, many wild species lose habitat to human development. The Western Cape of South Africa contains one of Earth's 35 biodiversity hotspots, with remarkably high levels of species richness and endemism. Understanding the relationship between anthropogenic changes and key species in this region is crucial for conservation of its threatened ecosystems. The objective of this research was to investigate the effect that climate change and urbanization each have on habitat suitability of the Cape Vulture. This research utilized NASA satellite data and crowdsourced species sightings to model past, current, and future habitat suitability for this key species in the Western Cape. Data used from NASA Earth Observations included: Landsat 8- derived Land Cover, Modis Land Surface Temperature, Digital Elevation Models from the Shuttle Radar Topography Mission, and precipitation data which integrated in-situ stations with Infrared data. Species observations were sourced from the Global Biodiversity Information Facility online database. A geospatial modelling framework was used to generate maps of present, past and future suitable habitats for analysis and comparison. Changes in precipitation and temperature may be a factor in the extreme loss of habitat since 1995, and predict even more drastic loss in the future. This research provides insights on anthropogenic effects on a species' range which may be used to inform discussions of conservation as an element of environmentally sustainable development.

Environmental Restoration of Diesel-Range Organics from Project Chariot, Cape Thompson, Alaska

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kautsky, Mark; Hutton, Rick; Miller, Judy

The Chariot site is located in the Ogotoruk Valley in the Cape Thompson region of northwest Alaska. Project Chariot was part of the Plowshare Program, created in 1957 by the US Atomic Energy Commission (AEC), a predecessor agency of the US Department of Energy (DOE), to study peaceful uses for atomic energy. Project Chariot began in 1958 when a scientific field team chose Cape Thompson as a potential site to excavate a harbor using a series of nuclear explosions. AEC, with assistance from other agencies, conducted more than 40 pretest bioenvironmental studies of the Cape Thompson area between 1959 andmore » 1962; however, the Plowshare Program work at the Project Chariot site (Figure 1) was cancelled because of strong public opposition [1]. No nuclear explosions were ever conducted at the site.« less

Preventive Role of Specific Dietary Factors and Natural Compounds Against DNA Damage and Oxidative Stress.

DTIC Science & Technology

1998-08-01

vitamins (C and E) and natural compounds (caffeic acid phenethyl ester [CAPE] and epigallocatechin gallate [ EGCG ] may be protective against mammary...caffeic acid phenethyl ester (CAPE), and epigallocatechin gallate ( EGCG ) in inhibiting DNA damage. These antioxidants are found in natural products such...as fruits and vegetables (vitamins C and E), the popular medicine honeybee propolis (CAPE), or green tea ( EGCG ). Studies carried out to date suggest

Cape Blanco wind farm feasibility study

NASA Astrophysics Data System (ADS)

1987-11-01

The Cape Blanco Wind Farm (CBWF) Feasibility Study was undertaken as a prototype for determining the feasibility of proposals for wind energy projects at Northwest sites. It was intended to test for conditions under which wind generation of electricity could be commercially feasible, not by another abstract survey of alternative technologies, but rather through a site-specific, machine-specific analysis of one proposal. Some of the study findings would be most pertinent to the Cape Blanco site - local problems require local solutions. Other findings would be readily applicable to other sites and other machines, and study methodologies would be designed to be modified for appraisal of other proposals. This volume discusses environmental, economic, and technical issues of the Wind Farm.

Genetic variation in natural honeybee populations, Apis mellifera capensis

NASA Astrophysics Data System (ADS)

Hepburn, Randall; Neumann, Peter; Radloff, Sarah E.

2004-09-01

Genetic variation in honeybee, Apis mellifera, populations can be considerably influenced by breeding and commercial introductions, especially in areas with abundant beekeeping. However, in southern Africa apiculture is based on the capture of wild swarms, and queen rearing is virtually absent. Moreover, the introduction of European subspecies constantly failed in the Cape region. We therefore hypothesize a low human impact on genetic variation in populations of Cape honeybees, Apis mellifera capensis. A novel solution to studying genetic variation in honeybee populations based on thelytokous worker reproduction is applied to test this hypothesis. Environmental effects on metrical morphological characters of the phenotype are separated to obtain a genetic residual component. The genetic residuals are then re-calculated as coefficients of genetic variation. Characters measured included hair length on the abdomen, width and length of wax plate, and three wing angles. The data show for the first time that genetic variation in Cape honeybee populations is independent of beekeeping density and probably reflects naturally occurring processes such as gene flow due to topographic and climatic variation on a microscale.

A total extinction confidently hoped for: the destruction of Cape San society under Dutch colonial rule, 1700-1795.

PubMed

Adhikari, Mohamed

2010-01-01

San (Bushman) society in the Cape Colony was almost completely annihilated during the eighteenth and nineteenth centuries as a result of land confiscation, massacre, forced labour and cultural suppression that accompanied colonial rule. Whereas similar obliterations of indigenous peoples in other parts of the world have resulted in major public controversies and heated debate amongst academics about the genocidal nature of these episodes, in South Africa the issue has effectively been ignored aside from passing, often polemical, references to it as genocide. Even recent studies that have approached the mass killing of the Cape San with sensitivity and insight do not address it as a case of genocide. This article sets out to redress this imbalance in part by analysing the dynamic of frontier conflict between San and settler under Dutch colonial rule as genocide. It demonstrates both the exterminatory intent underlying settler violence as well as the complicity of a weak colonial state in these depredations, including its sanctioning of the root-and-branch eradication of the San.

The potential effects of climate-change-associated temperature increases on the metabolic rate of a small Afrotropical bird.

PubMed

Thompson, Lindy J; Brown, Mark; Downs, Colleen T

2015-05-15

Studies have only recently begun to underline the importance of including data on the physiological flexibility of a species when modelling its vulnerability to extinction from climate change. We investigated the effects of a 4°C increase in ambient temperature (Ta), similar to that predicted for southern Africa by the year 2080, on certain physiological variables of a 10-12 g passerine bird endemic to southern Africa, the Cape white-eye Zosterops virens. There was no significant difference in resting metabolism, body mass and intraperitoneal body temperature between birds housed indoors at 4°C above outside ambient temperature and those housed indoors at outside ambient temperature. We conclude that the physiological flexibility of Cape white-eyes will aid them in coping with the 4°C increase predicted for their range by 2080. © 2015. Published by The Company of Biologists Ltd.

The evolution of the medical workforce in Cape Verde since independence in 1975.

PubMed

Delgado, A P; Tolentino, A C; Ferrinho, P

2017-01-18

Cape Verdean doctors have always graduated abroad. The first experience of pre-graduate medical education in Cape Verde begun in October 2015. Counting how many doctors Cape Verde has, knowing who they are, and knowing how they are distributed are very important to help fine-tune the medical training. The aim of this study is to analyze the evolution of the medical workforce in Cape Verde to support medical education implementation. Secondary data on doctors, from July 1975 until December 2014, collected from the Ministry of Health, were entered into an SPSS 20 database and studied by a simple descriptive statistical analysis. The database included data on 401 medical doctors. There was a predominance of females (n = 218; 54.4%). The overwhelming majority (n = 378; 94.3%) graduated from 5 of the 17 countries that contributed to the training of Cape Verdean doctors. All the islands of this archipelago country contributed to the 324 (80.8%) doctors born in the country. Of the 272 doctors still active in December 2014, 119 (43.6%) were general practitioners and 153 (56.4%) had specialized in one of the 31 specialties. The national ratio of doctors per 10 000 inhabitants was 5.25, but the reality varied significantly among islands. About one third of the doctors (n = 86; 32%) were at the primary care level, 38 (14%) at the secondary care level, and 144 (52%) in central hospitals. In 2053, all active physicians in 2014 will already be retired. This is a unique study of the evolution of the medical workforce of a country over 40 years, from the first day of independence. The study illustrates the importance of international collaborations, particularly of Cuba, in sustaining the medical workforce in Cape Verde. It is an example of how this collaboration was used to equip the country with doctors in an increasingly more equitable distribution across all islands. The study further illustrates the progressive feminization of the medical workforce. The study clarifies the effort required from the emerging medical faculty to supply the national health system with the needed number of doctors.

Caffeic acid phenethyl ester protects 661W cells from H2O2-mediated cell death and enhances electroretinography response in dim-reared albino rats

PubMed Central

Chen, Hui; Tran, Julie-Thu A.; Anderson, Robert E.

2012-01-01

Purpose Caffeic acid phenethyl ester (CAPE), an active component of honeybee propolis, has a wide range of beneficial properties. The purpose of this study was to test the protective role of CAPE in 661W cells (in vitro) against H2O2-mediated cell death and in albino rats (in vivo) against various light conditions. Methods The 661W cells were pretreated with CAPE and then stressed with H2O2. Cell death was measured with lactate dehydrogenase (LDH) release assay, and mRNA and proteins were analyzed. Sprague Dawley rats were raised on either a control or CAPE (0.02%) diet and exposed to various light conditions for short or long periods. Retinal histology, mRNA, protein, lipid composition, and retinal function by electroretinography (ERG) were measured at the end of feeding. Results Pretreatment of 661W cells with CAPE reduced H2O2-mediated cell death in a dose-dependent manner and induced expression of heme oxygenase-1 (Ho1). Albino rats fed with CAPE had greater expression of Ho1 and intercellular adhesion molecule 1 (Icam1), less expression of FOS-like antigen (Fosl) and lipoxygenase 12 (Lox12) genes in the retina, less translocation of nuclear factor kappaB protein to the nucleus, and a lower molar ratio of n-3 polyunsaturated fatty acids. Further, the ERGs of the retinas of CAPE-fed rats were significantly higher than those of the control-fed rats when raised in dim light. Conclusions CAPE can activate the antioxidative gene expression pathway in retinal cells in vitro and in vivo. Feeding CAPE to albino rats can enhance ERG responses and change the lipid profile in the rats’ retinas. PMID:22690111

Geostationary Coastal and Air Pollution Events (GEO CAPE) Instrument Performance Study

NASA Technical Reports Server (NTRS)

Mannino, Antonio; Hartman, Kathy R.

2014-01-01

The Ultimate objective of the GEO-CAPE 2014 study: Quantify the cost impact of very specific changes in instrument performance! The customer has defined 4 instrument types they are notionally interested in:! FR: Filter Radiometer! WAS: Wide Angle Spectrometer! MSS: Multi Slit Spectrometer! SSS: Single Slit Spectrometer.

The UNESCO biosphere reserve concept as a tool for urban sustainability: the CUBES Cape Town case study.

PubMed

Stanvliet, R; Jackson, J; Davis, G; De Swardt, C; Mokhoele, J; Thom, Q; Lane, B D

2004-06-01

The Cape Town Case Study (CTCS) was a multi-institutional collaborative project initiated by CUBES, a knowledge networking initiative of UNESCO's Ecological Sciences Division and the Earth Institute at Columbia University. Cape Town was selected as a CUBES site on the basis of its high biological and cultural significance, together with its demonstrated leadership in promoting urban sustainability. The CTCS was conducted by the Cape Town Urban Biosphere Group, a cross-disciplinary group of specialists drawn from national, provincial, municipal, and civil society institutions, mandated to examine the potential value of the UNESCO Biosphere Reserve concept as a tool for environmental management, social inclusion, and poverty alleviation in Cape Town. This article provides a contextualization of the CTCS and its collaborative process. It also reviews the biosphere reserve concept relative to urban sustainability objectives and proposes a more functional application of that concept in an urban context. A detailed analysis of key initiatives at the interface of conservation and poverty alleviation is provided in table format. Drawing on an examination of successful sustainability initiatives in Cape Town, specific recommendations are made for future application of the biosphere reserve concept in an urban context, as well as a model by which urban areas might affiliate with the UNESCO World Network of Biosphere Reserves, and criteria for such affiliation.

Phonological Neighborhood Effects in Spoken Word Production: An fMRI Study

ERIC Educational Resources Information Center

Peramunage, Dasun; Blumstein, Sheila E.; Myers, Emily B.; Goldrick, Matthew; Baese-Berk, Melissa

2011-01-01

The current study examined the neural systems underlying lexically conditioned phonetic variation in spoken word production. Participants were asked to read aloud singly presented words, which either had a voiced minimal pair (MP) neighbor (e.g., cape) or lacked a minimal pair (NMP) neighbor (e.g., cake). The voiced neighbor never appeared in the…

Child Adjustment and Parent Efficacy Scale-Developmental Disability (CAPES-DD): First psychometric evaluation of a new child and parenting assessment tool for children with a developmental disability.

PubMed

Emser, Theresa S; Mazzucchelli, Trevor G; Christiansen, Hanna; Sanders, Matthew R

2016-01-01

This study examined the psychometric properties of the Child Adjustment and Parent Efficacy Scale-Developmental Disability (CAPES-DD), a brief inventory for assessing emotional and behavioral problems of children with developmental disabilities aged 2- to 16-years, as well as caregivers' self-efficacy in managing these problems. A sample of 636 parents participated in the study. Children's ages ranged from 2 to 15. Exploratory and confirmatory factor analyses supported a 21-item, three-factor model of CAPES-DD child adjustment with 13 items describing behavioral (10 items) and emotional (3 items) problems and 8 items describing prosocial behavior. Three additional items were included due to their clinical usefulness and contributed to a Total Problem Score. Factor analyses also supported a 16-item, one factor model of CAPES-DD self-efficacy. Psychometric evaluation of the CAPES-DD revealed scales had satisfactory to very good internal consistency, as well as very good convergent and predictive validity. The instrument is to be in the public domain and free for practitioners and researchers to use. Potential uses of the measure and implications for future validation studies are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

Is a changing climate affecting the tropical cyclone behavior of Cape Verde?

NASA Astrophysics Data System (ADS)

Emmenegger, T. W.; Mann, M. E.; Evans, J. L.

2016-12-01

An existing dataset of synthetic tropical cyclone (TC) tracks derived from climate change simulations were used to explore TC variability within a 250 km radius of the Cape Verde Islands (16.5388N, 23.0418W). The synthetic sets were examined according to genesis point location, track projection, intensity, frequency, and seasonality within the observational era (1851 AD to present). These factors of TC variability have been shown to be strongly related to climate oscillations, thus the historical era was grouped by the increasing and decreasing regimes of sea surface temperature (SST) in the main development region (MDR) of the Atlantic Ocean. Numerous studies have examined Atlantic Basin activity throughout this era; the goal of this study is to investigate possible variations in TC behavior around Cape Verde, ultimately determining whether Cape Verde experiences similar fluctuations in activity as observed basin-wide. We find that several facets of TC variability such as intensity, seasonality, and genesis point location around Cape Verde are not significantly different to that of the entire basin, thus forecasts of the entire basin in these respects may also apply to our site. A long-term trend of increasing TC frequency can be identified basin-wide within the observed set, yet activity around Cape Verde does not display this same behavior observably or in any synthetic set. A relationship between the location of genesis points and the regimes of SST fluctuation is shown to be existent. We find both more observed and synthetic genesis points within the vicinity of Cape Verde during cool periods, and an eastward and equatorward shift in cyclogenesis is evident during warm regimes. This southeastern shift in genesis points attributes to the increased intensities of TCs seen during periods of warmer SST. Years of increased SST are additionally linked to an earlier seasonality in Cape Verde.

46 CFR 7.45 - Cape Henlopen, DE to Cape Charles, VA.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Cape Henlopen, DE to Cape Charles, VA. 7.45 Section 7.45 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.45 Cape Henlopen, DE to Cape Charles, VA. (a) A line drawn from the easternmost...

The Foraging Ecology of the Endangered Cape Verde Shearwater, a Sentinel Species for Marine Conservation off West Africa.

PubMed

Paiva, Vitor H; Geraldes, Pedro; Rodrigues, Isabel; Melo, Tommy; Melo, José; Ramos, Jaime A

2015-01-01

Large Marine Ecosystems such as the Canary Current system off West Africa sustains high abundance of small pelagic prey, which attracts marine predators. Seabirds are top predators often used as biodiversity surrogates and sentinel species of the marine ecosystem health, thus frequently informing marine conservation planning. This study presents the first data on the spatial (GPS-loggers) and trophic (stable isotope analysis) ecology of a tropical seabird-the endangered Cape Verde shearwater Calonectris edwardsii-during both the incubation and the chick-rearing periods of two consecutive years. This information was related with marine environmental predictors (species distribution models), existent areas of conservation concern for seabirds (i.e. marine Important Bird Areas; marine IBAs) and threats to the marine environment in the West African areas heavily used by the shearwaters. There was an apparent inter-annual consistency on the spatial, foraging and trophic ecology of Cape Verde shearwater, but a strong alteration on the foraging strategies of adult breeders among breeding phases (i.e. from incubation to chick-rearing). During incubation, birds mostly targeted a discrete region off West Africa, known by its enhanced productivity profile and thus also highly exploited by international industrial fishery fleets. When chick-rearing, adults exploited the comparatively less productive tropical environment within the islands of Cape Verde, at relatively close distance from their breeding colony. The species enlarged its trophic niche and increased the trophic level of their prey from incubation to chick-rearing, likely to provision their chicks with a more diversified and better quality diet. There was a high overlap between the Cape Verde shearwaters foraging areas with those of European shearwater species that overwinter in this area and known areas of megafauna bycatch off West Africa, but very little overlap with existing Marine Important Bird Areas. Further investigation on the potential nefarious effects of fisheries on seabird communities exploiting the Canary Current system off West Africa is needed. Such negative effects could be alleviated or even dissipated if the 'fisheries-conservation hotspots' identified for the region, would be legislated as Marine Protected Areas.

The Foraging Ecology of the Endangered Cape Verde Shearwater, a Sentinel Species for Marine Conservation off West Africa

PubMed Central

Paiva, Vitor H.; Geraldes, Pedro; Rodrigues, Isabel; Melo, Tommy; Melo, José; Ramos, Jaime A.

2015-01-01

Large Marine Ecosystems such as the Canary Current system off West Africa sustains high abundance of small pelagic prey, which attracts marine predators. Seabirds are top predators often used as biodiversity surrogates and sentinel species of the marine ecosystem health, thus frequently informing marine conservation planning. This study presents the first data on the spatial (GPS-loggers) and trophic (stable isotope analysis) ecology of a tropical seabird—the endangered Cape Verde shearwater Calonectris edwardsii–during both the incubation and the chick-rearing periods of two consecutive years. This information was related with marine environmental predictors (species distribution models), existent areas of conservation concern for seabirds (i.e. marine Important Bird Areas; marine IBAs) and threats to the marine environment in the West African areas heavily used by the shearwaters. There was an apparent inter-annual consistency on the spatial, foraging and trophic ecology of Cape Verde shearwater, but a strong alteration on the foraging strategies of adult breeders among breeding phases (i.e. from incubation to chick-rearing). During incubation, birds mostly targeted a discrete region off West Africa, known by its enhanced productivity profile and thus also highly exploited by international industrial fishery fleets. When chick-rearing, adults exploited the comparatively less productive tropical environment within the islands of Cape Verde, at relatively close distance from their breeding colony. The species enlarged its trophic niche and increased the trophic level of their prey from incubation to chick-rearing, likely to provision their chicks with a more diversified and better quality diet. There was a high overlap between the Cape Verde shearwaters foraging areas with those of European shearwater species that overwinter in this area and known areas of megafauna bycatch off West Africa, but very little overlap with existing Marine Important Bird Areas. Further investigation on the potential nefarious effects of fisheries on seabird communities exploiting the Canary Current system off West Africa is needed. Such negative effects could be alleviated or even dissipated if the ‘fisheries-conservation hotspots’ identified for the region, would be legislated as Marine Protected Areas. PMID:26436804

Implementing community participation through legislative reform: a study of the policy framework for community participation in the Western Cape province of South Africa

PubMed Central

2012-01-01

Background Amidst an evolving post-apartheid policy framework for health, policymakers have sought to institutionalize community participation in Primary Health Care, recognizing participation as integral to realizing South Africa’s constitutional commitment to the right to health. With evolving South African legislation supporting community involvement in the health system, early policy developments focused on Community Health Committees (HCs) as the principal institutions of community participation. Formally recognized in the National Health Act of 2003, the National Health Act deferred to provincial governments in establishing the specific roles and functions of HCs. As a result, stakeholders developed a Draft Policy Framework for Community Participation in Health (Draft Policy) to formalize participatory institutions in the Western Cape province. Methods With the Draft Policy as a frame of analysis, the researchers conducted documentary policy analysis and semi-structured interviews on the evolution of South African community participation policy. Moving beyond the specific and unique circumstances of the Western Cape, this study analyzes generalizable themes for rights-based community participation in the health system. Results Framing institutions for the establishment, appointment, and functioning of community participation, the Draft Policy proposed a formal network of communication – from local HCs to the health system. However, this participation structure has struggled to establish itself and function effectively as a result of limitations in community representation, administrative support, capacity building, and policy commitment. Without legislative support for community participation, the enactment of superseding legislation is likely to bring an end to HC structures in the Western Cape. Conclusions Attempts to realize community participation have not adequately addressed the underlying factors crucial to promoting effective participation, with policy reforms necessary: to codify clearly defined roles and functions of community representation; to outline how communities engage with government through effective and accountable channels for participation; and to ensure extensive training and capacity building of community representatives. Given the public health importance of structured and effective policies for community participation, and the normative importance of participation in realizing a rights-based approach to health, this analysis informs researchers on the challenges to institutionalizing participation in health systems policy and provides practitioners with a research base to frame future policy reforms. PMID:22920557

Long-term monitoring reveals cold-water corals in extreme conditions off the southeast US coast

NASA Astrophysics Data System (ADS)

Mienis, F.; Duineveld, G.; Davies, A. J.; Ross, S. W.; Lavaleye, M.; Van Weering, T.

2011-12-01

Cold-water corals are common on the SE slope of the US (SEUS) from Florida to Cape Hatteras between depths of 400-600 m. Near Cape Hatteras cold-water corals have formed mound structures that are up to 60 m high, which are mainly covered by living colonies of the coral species Lophelia pertusa. Past explorations of major reef sites of N Carolina using remote and manned submersibles have shown living Lophelia pertusa colonies on the current facing side of the mound structures and a high biodiversity of associated fauna, especially fish. The coral areas lie in the vicinity of the Gulf Stream characterized by strong currents transporting relatively warm water northwards along the SEUS slope. Thus far little is known about the environmental conditions inside the SEUS coral communities and particularly the effects of the nearby Gulf Stream. In December 2009 two autonomous benthic landers were deployed amidst Lophelia reefs off Cape Lookout (NC) for a period of 6 months to define oceanographic patterns that are relevant for the development and persistence of cold-water coral ecosystems. Landers recorded temperature, fluorescence, turbidity, and current speed and direction. Furthermore, a sediment trap was mounted on the landers that collected material at a 16-days interval. A first analysis of the lander data shows that instability of the Gulf Stream causes rapid rises in temperature, current speed and turbidity lasting for days to more than a week. Peak temperature and turbidity levels are the highest measured in coral habitats studied so far. We did not see clear cut effects of Gulf Stream instabilities on the near bed flux of phytodetritus as opposed to reports of meanders inducing upwelling and enhanced production in the photic zone. Data analyzed so far suggest that cwc habitats of Cape Lookout experience extreme and adverse conditions for prolonged periods. The findings of this study are compared with methodologically similar studies that have been conducted in coral habitats in the Gulf of Mexico and in the eastern North Atlantic.

Studying - Astronaut John H. Glenn, Jr. - Mercury-Atlas (MA)-6 - Cape

NASA Image and Video Library

1961-01-01

S61-04546 (1961) --- Astronaut John H. Glenn Jr., pilot of the Mercury-Atlas 6 (MA-6) "Friendship 7" mission, takes part in spacecraft systems briefing during preflight activity at Cape Canaveral, Florida. Photo credit: NASA

46 CFR 7.155 - Cape Spencer, AK to Cape St. Elias, AK.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Cape Spencer, AK to Cape St. Elias, AK. 7.155 Section 7.155 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.155 Cape Spencer, AK to Cape St. Elias, AK. (a) A line drawn from the westernmost...

46 CFR 7.155 - Cape Spencer, AK to Cape St. Elias, AK.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Cape Spencer, AK to Cape St. Elias, AK. 7.155 Section 7.155 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.155 Cape Spencer, AK to Cape St. Elias, AK. (a) A line drawn from the westernmost...

46 CFR 7.155 - Cape Spencer, AK to Cape St. Elias, AK.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Cape Spencer, AK to Cape St. Elias, AK. 7.155 Section 7.155 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.155 Cape Spencer, AK to Cape St. Elias, AK. (a) A line drawn from the westernmost...

46 CFR 7.155 - Cape Spencer, AK to Cape St. Elias, AK.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Cape Spencer, AK to Cape St. Elias, AK. 7.155 Section 7.155 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.155 Cape Spencer, AK to Cape St. Elias, AK. (a) A line drawn from the westernmost...

46 CFR 7.155 - Cape Spencer, AK to Cape St. Elias, AK.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Cape Spencer, AK to Cape St. Elias, AK. 7.155 Section 7.155 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.155 Cape Spencer, AK to Cape St. Elias, AK. (a) A line drawn from the westernmost...

75 FR 54770 - Drawbridge Operation Regulations; Cape Fear River and Northeast Cape Fear River, in Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-09

... Regulations; Cape Fear River and Northeast Cape Fear River, in Wilmington, NC AGENCY: Coast Guard, DHS. ACTION..., mile 26.8, and the Isabel S. Holmes Bridge, across Northeast Cape Fear River, mile 1.0, both in... Isabel S. Holmes Bridge, across Northeast Cape Fear River, mile 1.0, a bascule lift bridge, has a...

76 FR 39298 - Drawbridge Operation Regulation; Cape Fear River, and Northeast Cape Fear River, in Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-06

... Operation Regulation; Cape Fear River, and Northeast Cape Fear River, in Wilmington, NC AGENCY: Coast Guard... Northeast Cape Fear River, at mile 1.0, both in Wilmington, NC. The deviation restricts the operation of the... across Northeast Cape Fear River, at mile 1.0, both in Wilmington, NC, requested a temporary deviation...

Low concentrations of persistent organic pollutants (POPs) in air at Cape Verde.

PubMed

Nøst, Therese Haugdahl; Halse, Anne Karine; Schlabach, Martin; Bäcklund, Are; Eckhardt, Sabine; Breivik, Knut

2018-01-15

Ambient air is a core medium for monitoring of persistent organic pollutants (POPs) under the Stockholm Convention and is used in studies of global transports of POPs and their atmospheric sources and source regions. Still, data based on active air sampling remain scarce in many regions. The primary objectives of this study were to (i) monitor concentrations of selected POPs in air outside West Africa, and (ii) to evaluate potential atmospheric processes and source regions affecting measured concentrations. For this purpose, an active high-volume air sampler was installed on the Cape Verde Atmospheric Observatory at Cape Verde outside the coast of West Africa. Sampling commenced in May 2012 and 43 samples (24h sampling) were collected until June 2013. The samples were analyzed for selected polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), hexachlorobenzene (HCB) and chlordanes. The concentrations of these POPs at Cape Verde were generally low and comparable to remote sites in the Arctic for several compounds. Seasonal trends varied between compounds and concentrations exhibited strong temperature dependence for chlordanes. Our results indicate net volatilization from the Atlantic Ocean north of Cape Verde as sources of these POPs. Air mass back trajectories demonstrated that air masses measured at Cape Verde were generally transported from the Atlantic Ocean or the North African continent. Overall, the low concentrations in air at Cape Verde were likely explained by absence of major emissions in areas from which the air masses originated combined with depletion during long-range atmospheric transport due to enhanced degradation under tropical conditions (high temperatures and concentrations of hydroxyl radicals). Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

Sleep in the Cape Mole Rat: A Short-Sleeping Subterranean Rodent.

PubMed

Kruger, Jean-Leigh; Gravett, Nadine; Bhagwandin, Adhil; Bennett, Nigel C; Archer, Elizabeth K; Manger, Paul R

2016-01-01

The Cape mole rat Georychus capensis is a solitary subterranean rodent found in the western and southern Cape of South Africa. This approximately 200-gram bathyergid rodent shows a nocturnal circadian rhythm, but sleep in this species is yet to be investigated. Using telemetric recordings of the electroencephalogram (EEG) and electromyogram (EMG) in conjunction with video recordings, we were able to show that the Cape mole rat, like all other rodents, has sleep periods composed of both rapid eye movement (REM) and slow-wave (non-REM) sleep. These mole rats spent on average 15.4 h awake, 7.1 h in non-REM sleep and 1.5 h in REM sleep each day. Cape mole rats sleep substantially less than other similarly sized terrestrial rodents but have a similar percentage of total sleep time occupied by REM sleep. In addition, the duration of both non-REM and REM sleep episodes was markedly shorter in the Cape mole rat than has been observed in terrestrial rodents. Interestingly, these features (total sleep time and episode duration) are similar to those observed in another subterranean bathyergid mole rat, i.e. Fukomys mechowii. Thus, there appears to be a bathyergid type of sleep amongst the rodents that may be related to their environment and the effect of this on their circadian rhythm. Investigating further species of bathyergid mole rats may fully define the emerging picture of sleep in these subterranean African rodents. © 2016 S. Karger AG, Basel.

A Systems Dynamic Model for Drug Abuse and Drug-Related Crime in the Western Cape Province of South Africa

PubMed Central

Coetzee, Lezanie

2017-01-01

The complex problem of drug abuse and drug-related crimes in communities in the Western Cape province cannot be studied in isolation but through the system they are embedded in. In this paper, a theoretical model to evaluate the syndemic of substance abuse and drug-related crimes within the Western Cape province of South Africa is constructed and explored. The dynamics of drug abuse and drug-related crimes within the Western Cape are simulated using STELLA software. The simulation results are consistent with the data from SACENDU and CrimeStats SA, highlighting the usefulness of such a model in designing and planning interventions to combat substance abuse and its related problems. PMID:28555161

Latitudinal patterns in the life-history traits of three isolated Atlantic populations of the deep-water shrimp Plesionika edwardsii (Decapoda, Pandalidae)

NASA Astrophysics Data System (ADS)

González, José A.; Pajuelo, José G.; Triay-Portella, Raül; Ruiz-Díaz, Raquel; Delgado, João; Góis, Ana R.; Martins, Albertino

2016-11-01

Patterns in the life-history traits of the pandalid shrimp Plesionika edwardsii are studied for the first time in three isolated Atlantic populations (Madeira, Canaries and Cape Verde Islands) to gain an understanding of their latitudinal variations. The maximum carapace size of the populations studied, as well as the maximum weight, showed clear latitudinal patterns. The patterns observed may be a consequence of the temperature experienced by shrimps during development, 1.37 ° C higher in the Canaries and 5.96 ° C higher in the Cape Verde Islands than in Madeira. These temperature differences among populations may have induced phenotypic plasticity because the observed final body size decreased as the temperature increased. A latitudinal north-south pattern was also observed in the maximum size of ovigerous females, with larger sizes found in the Madeira area and lower sizes observed in the Cape Verde Islands. A similar pattern was observed in the brood size and maximum egg size. Females of P. edwardsii produced smaller eggs in the Cape Verde Islands than did those at the higher latitude in Madeira. P. edwardsii was larger at sexual maturity in Madeira than in the Cape Verde Islands. The relative size at sexual maturity is not affected by latitude or environmental factors and is the same in the three areas studied, varying slightly between 0.568 and 0.585. P. edwardsii had a long reproductive season with ovigerous females observed all year round, although latitudinal variations were observed. Seasonally, there were more ovigerous females in spring and summer in Madeira and from winter to summer in the Cape Verde Islands. P. edwardsii showed a latitudinal pattern in size, with asymptotic size and growth rate showing a latitudinal compensation gradient as a result of an increased growth performance in the Madeira population compared to that of the Cape Verde Islands.

Long-term Neurotoxic Effects of Early-life Exposure to Tetrachloroethylene-contaminated Drinking Water.

PubMed

Aschengrau, Ann; Janulewicz, Patricia A; White, Roberta F; Vieira, Veronica M; Gallagher, Lisa G; Getz, Kelly D; Webster, Thomas F; Ozonoff, David M

2016-01-01

Tetrachloroethene (PCE) is a common environmental and occupational contaminant and an acknowledged neurotoxicant. From 1968 through 1983, widespread contamination of public drinking water supplies with PCE occurred in the Cape Cod region of Massachusetts. The source of the contamination was a vinyl liner applied to the inner surface of water distribution pipes. A retrospective cohort study (the Cape Cod Health Study) was undertaken to examine possible health consequences of early-life exposure to PCE-contaminated drinking water. This review describes the study methods and findings regarding the effects of prenatal and childhood exposure on neurologic outcomes during early adulthood, including vision, neuropsychological functioning, brain structure, risky behaviors, and mental illness. The review also describes the strengths and challenges of conducting population-based epidemiologic research in this unique setting. Participants were identified by cross-matching birth certificates and water system data. Information on health outcomes and confounding variables was collected from self-administered surveys (n = 1689), neuropsychological tests (n = 63), vision examinations (n = 63), and magnetic resonance imaging (n = 42). Early-life exposure to PCE was estimated using a leaching and transport model. The data analysis compared the occurrence of each health outcome among individuals with prenatal and early childhood PCE exposure to unexposed individuals while considering the effect of confounding variables. The study found evidence that early-life exposure to PCE-contaminated drinking water has long-term neurotoxic effects. The strongest associations were seen with illicit drug use, bipolar disorder, and post-traumatic stress disorder. Key strengths of the study were availability of historical data on affected water systems, a relatively high exposure prevalence and wide range of exposure levels, and little confounding. Challenges arose mainly from the historical nature of the exposure assessments. The Cape Cod Health Study demonstrates how scientists can take advantage of unique "natural experiments" to learn about the health effects of environmental pollution. This body of work has improved our understanding of the long-term health effects of early-life exposure to this common environmental contaminant and will help risk assessors and policymakers ensure that drinking water supplies in the United States are safe for vulnerable populations. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

46 CFR 7.55 - Cape Henry, VA to Cape Fear, NC.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Cape Henry, VA to Cape Fear, NC. 7.55 Section 7.55 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.55 Cape Henry, VA to Cape Fear, NC. (a) A line drawn from Rudee Inlet Jetty Light “2” to...

Estimation of hydraulic parameters from an unconfined aquifer test conducted in a glacial outwash deposit, Cape Cod, Massachusetts

USGS Publications Warehouse

Moench, Allen F.; Garabedian, Stephen P.; LeBlanc, Denis R.

2001-01-01

An aquifer test conducted in a sand and gravel, glacial outwash deposit on Cape Cod, Massachusetts was analyzed by means of a model for flow to a partially penetrating well in a homogeneous, anisotropic unconfined aquifer. The model is designed to account for all significant mechanisms expected to influence drawdown in observation piezometers and in the pumped well. In addition to the usual fluid-flow and storage processes, additional processes include effects of storage in the pumped well, storage in observation piezometers, effects of skin at the pumped-well screen, and effects of drainage from the zone above the water table.

Ecological correlates of multiple sexual partnerships among adolescents and young adults in urban Cape Town: a cumulative risk factor approach.

PubMed

Muchiri, Evans; Odimegwu, Clifford; Banda, Pamela; Ntoimo, Lorreta; Adedini, Sunday

2017-07-01

Studies in South Africa have reported unsafe levels of risky sexual behvaiours among adolescents and young adults, with the country reporting the highest burden of HIV/AIDS globally, as well as a high rate of teenage pregnancy. While determinants of risky sexual behaviours have been investigated for factors occurring at the individual and household levels, not fully explored in the literature is the effect of community level factors. Furthermore, it is unclear whether risk factors occurring within the ecology of adolescents and young adults act cumulatively to influence their sexual practices. This article aims to address this knowledge gap using a case study of the Cape Area Panel Study of adolescents and young adults in urban Cape Town, South Africa. The ecological framework was adopted to guide the selection of risk factors at the individual, household, and community levels. Multivariate linear discriminant function analyses were used to select significant risk factors for multiple sexual partnerships and used to produce risk indices for the respondents. The cumulative risk approach was applied to test whether significant risk factors acted cumulatively. Findings point to the importance of ecological factors in influencing outcomes of multiple sexual partnerships among respondents and further demonstrate that ecological risk factors may act cumulatively. These findings are important for South Africa that is grappling with teenage pregnancy and disproportionate HIV epidemic among the youth.

Northern Saw-whet Owls (Aegolius acadicus) captured at Cape May Point, NJ, 1980-1994: comparison of two capture techniques

Treesearch

Katharine E. Duffy; Patrick E. Matheny

1997-01-01

During autumn migration 1980-1994, 1,270 Northern Saw-whet Owls (Aegolius acadicus) (NSWO) were captured and banded at Cape May Point, NJ. From 1980-1988, captures were effected by passive mist-netting. From 1989-1994, an audiolure (NSWO territorial song broadcast loudly from dusk to dawn in the trapping area) was used to enhance capture rate. 638...

KSC-2011-2976

NASA Image and Video Library

2011-04-07

CAPE CANAVERAL, Fla. - At the Cape Canaveral Air Force Station forecast facility in Florida, a member of the weather team demonstrates the effectiveness of the new weather radar display recently installed. The facility is operated by the U.S. Air Force 45th Weather Squadron and will generate a launch weather forecast for the scheduled July 8 lift off of space shuttle Atlantis on the STS-135 mission. Photo credit: NASA/Jack Pfaller

KSC-2011-2975

NASA Image and Video Library

2011-04-07

CAPE CANAVERAL, Fla. - At the Cape Canaveral Air Force Station forecast facility in Florida, a member of the weather team demonstrates the effectiveness of the new weather radar display recently installed. The facility is operated by the U.S. Air Force 45th Weather Squadron and will generate a launch weather forecast for the scheduled July 8 lift off of space shuttle Atlantis on the STS-135 mission. Photo credit: NASA/Jack Pfaller

Coastal vulnerability assessment of Cape Hatteras National Seashore (CAHA) to sea-level rise

USGS Publications Warehouse

Pendleton, Elizabeth A.; Theiler, E. Robert; Williams, S. Jeffress

2005-01-01

A coastal vulnerability index (CVI) was used to map the relative vulnerability of the coast to future sea-level rise within Cape Hatteras National Seashore (CAHA) in North Carolina. The CVI ranks the following in terms of their physical contribution to sea-level rise-related coastal change: geomorphology, regional coastal slope, rate of relative sea-level rise, historical shoreline change rates, mean tidal range, and mean significant wave height. The rankings for each variable were combined and an index value was calculated for 1-minute grid cells covering the park. The CVI highlights those regions where the physical effects of sea-level rise might be the greatest. This approach combines the coastal system's susceptibility to change with its natural ability to adapt to changing environmental conditions, yielding a quantitative, although relative, measure of the park's natural vulnerability to the effects of sea-level rise. The CVI provides an objective technique for evaluation and long-term planning by scientists and park managers. Cape Hatteras National Seashore consists of stable and washover dominated segments of barrier beach backed by wetland and marsh. The areas within Cape Hatteras that are likely to be most vulnerable to sea-level rise are those with the highest occurrence of overwash and the highest rates of shoreline change.

3. View from former light tower to Cape Elizabeth Light ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. View from former light tower to Cape Elizabeth Light Tower, view northeast, southwest side of Cape Elizabeth Tower - Cape Elizabeth Light Station, Near Two Lights State Park at end of Two Lights Road, off State Highway 77, Cape Elizabeth, Cumberland County, ME

Long-Term Neurotoxic Effects of Early Life Exposure to Tetrachloroethylene-contaminated Drinking Water

PubMed Central

Aschengrau, Ann; Janulewicz, Patricia A.; White, Roberta F.; Vieira, Veronica M.; Gallagher, Lisa G.; Getz, Kelly D.; Webster, Thomas F.; Ozonoff, David M.

2016-01-01

Background Tetrachloroethene (PCE) is a common environmental and occupational contaminant and an acknowledged neurotoxicant. From 1968 through 1983 widespread contamination of public drinking water supplies with PCE occurred in the Cape Cod region of Massachusetts. The source of the contamination was a vinyl liner applied to the inner surface of water distribution pipes. Objectives A retrospective cohort study (“the Cape Cod Health Study”) was undertaken to examine possible health consequences of early life exposure to PCE-contaminated drinking water. This review describes the study methods and findings regarding the impact of prenatal and childhood exposure on neurological outcomes during early adulthood, including vision, neuropsychological functioning, brain structure, risky behaviors, and mental illness. The review also describes the strengths and challenges of conducting population-based epidemiological research in this unique setting. Methods Subjects were identified by cross-matching birth certificate and water system data. Information on health outcomes and confounding variables was collected from self-administered surveys (N= 1,689), neuropsychological tests (N=63), vision exam (N=63), and magnetic resonance imaging (N=42). Early life exposure to PCE was estimated using a leaching and transport model. The data analysis compared the occurrence of each health outcome among subjects with prenatal and early childhood PCE exposure to unexposed subjects while considering the impact of confounding variables. Results The study found evidence that early life exposure to PCE-contaminated drinking water has long-term neurotoxic effects. The strongest associations were seen with illicit drug use, bipolar disorder, and post-traumatic stress disorder. Key strengths of the study were availability of historical data on affected water systems, a relatively high exposure prevalence and wide range of exposure levels, and little confounding. Challenges arose mainly from the historical nature of the exposure assessments. Conclusions The Cape Cod Health Study demonstrates how scientists can take advantage of unique “natural experiments” to learn about the health effects of environmental pollution. This body of work has improved our understanding of the long-term health effects of early life exposure to this common environmental contaminant and will help risk assessors and policy makers ensure that U.S. drinking water supplies are safe for vulnerable populations. PMID:27325074

Theoretical and numerical studies on physics and dynamics of orographic precipitation associated with tropical cyclones over mesoscale mountains

NASA Astrophysics Data System (ADS)

Sever, Gokhan

A series of systematic two/three-dimensional (2D/3D) idealized numerical experiments were conducted to investigate the combined effects of dynamical and physical processes on orographic precipitation (OP) with varying incoming basic flow speed (U) and CAPE in a conditionally unstable uniform flow. The three moist flow regimes identified by Chu and Lin are reproduced using the CM1 model in low resolution (Deltax = 1 km) 2D simulations. A new flow regime, namely Regime IV (U > 36 m s-1) is characterized by gravity waves, heavy precipitation, lack of upper-level wave breaking and turbulence over the lee slope. The regime transition from III to IV at about 36 m s -1 can be explained by the transition from upward propagating gravity waves to evanescent flow, which can be predicted using a moist mountain wave theory. Although the basic features are captured well in low grid resolutions, high resolution (Deltax = 100 m) 2D/3D simulations are required to resolve precipitation distribution and intensity at higher basic winds (U > 30 m s -1). These findings may be applied to examine the performance of moist and turbulence parameterization schemes. Based on 3D simulations, gravity wave-induced severe downslope winds and turbulent mixing within hydraulic jump reduce OP in Regime III. Then in Regime IV, precipitation amount and spatial extent are intensified as the upper-level wave breaking vanishes and updrafts strengthen. Similar experiments were performed with a low CAPE sounding to assess the evolution of OP in an environment similar to that observed in tropical cyclones. These low CAPE simulations show that precipitation is nearly doubled at high wind speeds compared to high CAPE results. Based on a microphysics budget analysis, two factors are identified to explain this difference: 1) warm-rain formation processes (auto-conversion and accretion), which are more effective in low CAPE environment, and 2) even though rain production (via graupel and snow melting) is intense in high CAPE, strong downdrafts and advection induced evaporation tend to deplete precipitation before reaching the ground. Overall, both in 2D/3D high wind speed simulations, the pattern of the precipitation distribution resembles to the bell-shaped mountain profile with maximum located over the mountain peak. This result has a potential to simplify the parameterization of OP in terms of two control parameters and might applicable to global weather and climate modeling.

Character and distribution of exposed glaciodeltaic deposits off outer Cape Cod, Massachusetts, and their effects on hydrogeology and benthic habitats

USGS Publications Warehouse

Poppe, L.J.; Foster, D.S.; Danforth, W.W.

2006-01-01

Seabed outcrops of glaciodeltaic sediments were identified in four places east of Cape Cod, Massachusetts, during seismic-reflection, multibeam bathymetric and backscatter, bottom photographic, and sediment sampling surveys. These strata record coarser-grained ice-proximal glaciofluvial topset to finer-grained distal glaciolacustrine bottomset deposition within deltaic systems that prograded southwestward into glacial lakes from the South Channel lobe about 18 ka B.P. These beds are important because they (1) influence the outer Cape's hydrogeologic framework, and (2) constitute relatively stable, locally rough habitats within an area of seafloor dominated by mobile sand and gravelly sediment, and benefit the benthic fauna by providing shelter and a substrate amenable to burrow construction. ?? Springer-Verlag 2006.

Design, synthesis and pharmacological evaluation of (E)-3,4-dihydroxy styryl sulfonamides derivatives as multifunctional neuroprotective agents against oxidative and inflammatory injury.

PubMed

Ning, Xianling; Guo, Ying; Ma, Xiaoyan; Zhu, Renzong; Tian, Chao; Zhang, Zhili; Wang, Xiaowei; Ma, Zhizhong; Liu, Junyi

2013-09-01

A novel class of (E)-3,4-dihydroxy styryl sulfonamides and their 3,4-diacetylated derivatives as caffeic acid phenethyl ester (CAPE) analogs was designed and prepared for improving stability and solubility of the lead compound. Their neuroprotective properties were assessed by several models. The results showed that target compounds displayed positive free radical quenching abilities, superior to that of CAPE. Compounds 6j-k and 7j-k demonstrated remarkable protection effects against damage induced by hydrogen peroxide which were apparently stronger than that of CAPE. Most of target compounds could inhibit nitric oxide production. Additionally, target compounds showed high blood-brain barrier permeability. Copyright © 2013. Published by Elsevier Ltd.

KSC-84PC-0228

NASA Image and Video Library

1984-07-13

CAPE CANAVERAL, Fla. -- At Cape Canaveral Air Force Station in Florida, British engineers conduct tests on the United Kingdom Subsatellite, part of the three-spacecraft international Active Magnetospheric Particle Tracer Explorer AMPTE mission scheduled for launch on Aug. 9, 1984 aboard a Delta rocket. The 172-pound UKS contains a comprehensive set of plasma measuring instruments to record the effects of chemical clouds released by the West German built Ion Release Module. The other AMPTE spacecraft – the Charged Composition Explorer CCEUnited States) – will operate far below, from inside the Earth’s magnetosphere, where it will track the ionized clouds as it is swept along by the solar wind. With the CCE studying this activity from below, and the IRM and UKS studying it from above, scientists expect to acquire valuable new data on exactly how the solar wind interacts with the Earth’s magnetic fields. Photo Credit: NASA

A study of psychrophilic organisms isolated from the manufacture and assembly areas of spacecraft to be used in the Viking mission

NASA Technical Reports Server (NTRS)

Foster, T. L.; Winans, L., Jr.

1974-01-01

The ability of psychrophilic microorganisms to grow in some of the environmental conditions suggested for Mars is studied with particular attention given to the effects of moisture and nutrients on growth. Results of growth with the slide culture technique are presented and indicate that this technique can be a rapid and sensitive technique for demonstration of microbial growth under various environmental conditions. Additional soil samples have been obtained from Cape Kennedy, and results of these assays at various low temperatures for psychrophilic populations are presented. The heat resistance of some of the psychrophilic sporeformers have been determined. Psychrophilic organisms were isolated from the teflon ribbons at Cape Kennedy and characterization of these was begun. In addition, heat survivors from the teflon ribbons are being investigated, and partial characterizations of these are presented.

Testing of microsatellite multiplexes for individual identification of Cape Parrots (Poicephalus robustus): paternity testing and monitoring trade

PubMed Central

Coetzer, Willem G.; Downs, Colleen T.; Perrin, Mike R.

2017-01-01

Background Illegal trade in rare wildlife species is a major threat to many parrot species around the world. Wildlife forensics plays an important role in the preservation of endangered or threatened wildlife species. Identification of illegally harvested or traded animals through DNA techniques is one of the many methods used during forensic investigations. Natural populations of the South African endemic Cape Parrot (Poicephalus robustus) are negatively affected by the removal of eggs and chicks for the pet trade. Methods In this study, 16 microsatellite markers specifically designed for the South African endemic Cape Parrot (P. robustus) are assessed for their utility in forensic casework. Using these 16 loci, the genetic diversity of a subset of the captive Cape Parrot population was also assessed and compared to three wild Cape Parrot populations. Results It was determined that the full 16 locus panel has sufficient discriminatory power to be used in parentage analyses and can be used to determine if a bird has been bred in captivity and so can be legally traded or if it has been illegally removed from the wild. In cases where birds have been removed from the wild, this study suggests that a reduced 12 locus microsatellite panel has sufficient power to assign confiscated birds to geographic population of origin. Discussion The level of genetic diversity observed within the captive Cape Parrot population was similar to that observed in the wild populations, which suggests that the captive population is not suffering from decreased levels of genetic diversity. The captive Cape Parrots did however have double the number of private alleles compared to that observed in the most genetically diverse wild population. This is probably due to the presence of rare alleles present in the founder population, which has not been lost due to genetic drift, as many of the individuals tested in this study are F1–F3 wild descendants. The results from this study provide a suit of markers that can be used to aid conservation and law enforcement authorities to better control legal and illegal trade of this South African endemic. PMID:28344897

Cape Cod National Seashore alternative transportation systems long range planning study

DOT National Transportation Integrated Search

2003-05-01

This project involves the development of short-range and long-range plans for alternative transportation to, from, and within the Cape Cod National Seashore. The five-year plan notes that improved public transportation services are needed both to mit...

Orientation Programs and Student Retention in Distance Learning: The Case of University of Cape Coast

ERIC Educational Resources Information Center

Arhin, Vera; Wang'eri, Tabitha

2018-01-01

This study investigated how orientation programs predict student retention in distance learning at the University of Cape Coast. A correlational research design was employed for the study. The target population was level-200 students in the distance education program at the university. Seven hundred and twenty-seven participants were selected from…

Unusual megafaunal assemblages on the continental slope off Cape Hatteras

NASA Astrophysics Data System (ADS)

Hecker, Barbara

Megafaunal assemblages were studied in August-September 1992 using a towed camera sled along seven cross-isobath transects on the continental slope off Cape Hatteras. A total of 20,722 megafaunal organisms were observed on 10,918 m 2 of the sea floor between the depths of 157 and 1 924 m. These data were compared with data previously collected off Cape Hatteras in 1985 and at other locations along the eastern U.S. coast between 1981 and 1987. Megafaunal populations on the upper and lower slopes off Cape Hatteras were fouond to be similar, in terms of density and species composition, to those observed at the other locations. In contrast, megafaunal abundances were found to be elevated (0.88 and 2.65 individuals per m 2 during 1985 and 1992, respectively) on the middle slope off Cape Hatteras when compared to most other slope locations (<0.5individuals per m 2). These elevated abundances mainly reflect dense populations of three demersal fish, two eel pouts ( Lysenchelys verrilli and Lycodes atlanticus) and the witch flounder Glyptocephalus cynoglossus, and a large anemone ( Actinauge verrilli). These four species dominated the megafauna off Cape Hatteras, whereas they represented only a minor component of megafaunal populations found at other slope locations. Additionally, numerous tubes of the foraminiferan Bathysiphon filiformis were observed off Cape Hatteras, but not elsewhere. The high density of demersal fish found off Cape Hatteras appears to be related to the high densities of infaunal prey reported from this area. The high densities of A. verrilli and B. fuliformis may be related to the same factors responsible for the high infaunal densities, namely enhanced nutrient inputs in the form of fine particles. Extreme patchiness also was observed in the distributions of the middle slope taxa off Cape Hatteras. This patchiness may reflect the habitat heterogeneity of this exceptionally rugged slope and the sedentary nature of the organisms inhabiting it.

Differences in CAPE between wet and dry spells of the monsoon over the southeastern peninsular India

NASA Astrophysics Data System (ADS)

Mohan, T. S.; Rao, T. N.; Rajeevan, M.

2018-03-01

In the present research we explored the variability of convective available potential energy (CAPE) during wet and dry spells over southeast India. Comparison between India Meteorological Department (IMD) observations and reanalysis products (NCEP, ERA-interim, and MERRA) reconfirms that gridded data sets can be utilized to fill the void of observations. Later, GPS radiosonde measurements made at Gadanki (13.5 N, 79.2 E) Andre analysis output are utilized to address key scientific issues related to CAPE over the southeastern peninsular region. They are: (1) How does CAPE vary between different spells of the Indian summer monsoon (i.e., from wet to dry spell)? (2) Does differences in CAPE and in the vertical structure of buoyancy between spells are localized features over Gadanki or observed all over southeastern peninsular region? (3) What physical/dynamical processes are responsible for the differences in CAPE between spells and how do they affect the convection growth in dry spell? Interestingly, CAPE is higher in wet spell than in dry spell, in contrast to the observations made elsewhere over land and warm oceans. Similar feature (high CAPE in wet spell) is observed at all grid points in the southeastern peninsular India. Furthermore, vertical buoyancy profiles show only one peak in the middle-upper troposphere in wet spell, while two peaks are observed in most of the profiles (66%) in dry spell over the entire study region in all the reanalysis products. Plausible mechanisms are discussed for the observed CAPE differences. They are, among others, timing of sounding with reference to rain occurrence, rapid buildup of surface instabilities, moistening of lower troposphere by evaporation of the surface moisture in wet spell, enhanced low-level moisture convergence, evaporation of rain in relatively warm and dry atmosphere, and reduction of positive buoyancy in dry spell. The omnipresence of stable layers and strong and deep shear in the presence of weak updrafts (buoyancy) limits the growth of convective draft cores in dry spell.

Geology of the Woods Hole area, Massachusetts; the story behind the landscape

USGS Publications Warehouse

Hutchinson, D.R.; Schwarzman, Beth

2001-01-01

The geologic story of the Woods Hole area, Cape Cod, Mass., was written by glacial ice during the last ice age and edited by the ocean waves. If you learn to read today's landscape, you can see the fascinating history it records. The features of Cape Cod, from the ponds and cranberry bogs to the gently sloping sandy uplands and rocky, irregular hills to the beaches, result from the glacial processes that built the cape and the marine processes that still shape it. Many geologists since the late 19th century have contributed to telling this story. The U.S. Geological Survey has studied the geology of Cape Cod in order to provide people with objective scientific data that can be applied to wise stewardship of the land and coasts.

75 FR 81637 - Commercial Lease for the Cape Wind Energy Project

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

... Commercial Lease for the Cape Wind Energy Project AGENCY: Bureau of Ocean Energy Management, Regulation and... Renewable Energy Development on the Outer Continental Shelf (``OCS'') for the Cape Wind Energy Project... requirements of 30 CFR 285.231. The Lease is for the Cape Wind Energy Project (``Project'') which grants Cape...

Prospects for biological control of Cape-ivy with the Cape-ivy fly and the cape-ivy moth

USDA-ARS?s Scientific Manuscript database

Cape-ivy (Delairea odorata, Asteraceae), native to coastal floodplains and mountain riparian zones in eastern South Africa, is an invasive vine in coastal riparian, woodland and scrub habitats in California and southern Oregon. Cape-ivy smothers native vegetation and may impair water flow in coastal...

78 FR 9587 - Drawbridge Operation Regulation; Cape Fear River, Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... Operation Regulation; Cape Fear River, Wilmington, NC AGENCY: Coast Guard, DHS. ACTION: Notice of deviation... operating schedule that governs the operation of the Cape Fear River Memorial Bridge, across the Cape Fear.... The Cape Fear River Memorial Bridge, at mile 26.8, at Wilmington, NC, has vertical clearances in the...

33 CFR 80.505 - Cape Henlopen, DE to Cape Charles, VA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Cape Henlopen, DE to Cape Charles, VA. 80.505 Section 80.505 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Fifth District § 80.505 Cape Henlopen, DE...

Contribution of Water Pollution From Inadequate Sanitation and Housing Quality to Diarrheal Disease in Low-Cost Housing Settlements of Cape Town, South Africa

PubMed Central

Barnes, Jo M.; Pieper, Clarissa H.

2011-01-01

Objectives. We investigated the effects of failing sanitation, poor housing conditions, and fecal pollution in runoff water on the health—particularly the incidence of diarrheal disease—of residents of low-cost housing settlements in Cape Town, South Africa. Methods. In November 2009, we conducted a cross-sectional survey with structured interviews in 4 communities (n = 336 dwellings; 1080 persons). We used Colilert defined-substrate technology to determine Escherichia coli levels in runoff water samples taken from the study communities. Results. Almost 15% of households disposed of soiled products in storm water drains and 6% disposed of soiled products in the street. In only 26% of the dwellings were toilets washed daily. Approximately 59% of dwellings lacked a tap near the toilet for hand washing, and 14% of respondents suffered 1 or more attacks of diarrhea in the 2 weeks preceding their interview. E.coli counts of runoff environmental water samples ranged from 750 to 1 580 000 000 per 100 milliliters. Conclusions. A holistic and integrated approach is needed to improve housing quality and sanitation among Cape Town's low-income citizens. PMID:21566018

Assessment of metals exposure and sub-lethal effects in voles and small birds captured near the DeLong Mountain Regional Transportation System Road, Cape Krusenstern National Monument, Alaska, 2006

USGS Publications Warehouse

Brumbaugh, William G.; Mora, Miguel A.; May, Thomas W.

2008-01-01

Voles (n=6) and small ground-nesting birds (n=12) were live-captured near the DeLong Mountain Regional Transportation System haul road in Cape Krusenstern National Monument in northwest Alaska in 2006 to assess metals exposure and sub-lethal biological effects. Similar numbers of animals were captured from a reference site in southern Cape Krusenstern National Monument for comparison. Histopathological examination of selected organs, blood analysis, and analysis for aluminum, barium, cadmium, lead, and zinc concentrations in liver and blood samples were performed. Voles and small birds captured from near the haul road had about 20 times greater blood and liver lead concentrations and about 3 times greater cadmium concentrations when compared to those from the reference site. Barium and zinc tissue concentrations of animals collected from different sites were not remarkably different, and aluminum concentrations were below the reporting limits in most samples. There was no clear evidence of serious sub-lethal biological effects such as lesions in internal organs or DNA damage in blood in any of the animals. Accordingly, blood and liver lead concentrations in animals captured near the haul road generally were less than tissue concentration thresholds associated with serious biological effects reported from other studies; however, subtle effects resulting from lead exposure, such as the suppression of the activity of certain enzymes, cannot be ruled out for those animals nearest the haul road. Notably, liver lead concentrations of voles and small birds at the reference location were considerably less than those previously reported for similar animals at reference sites in other parts of the United States, Canada, and Europe. Results from this reconnaissance-level study indicate that voles and small birds inhabiting this area are not suffering serious biological effects as a result of metals exposure; however, continued monitoring of lead and other metals is recommended because of uncertainties noted and because biological effects thresholds might be approached if exposure levels were to increase.

76 FR 40725 - Approval of Outer Continental Shelf (OCS) Permit Issued to Cape Wind Associates, LLC (EPA Permit...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

... Cape Wind Associates, LLC (Cape Wind). The OCS permit, which was issued pursuant to regulations, authorizes Cape Wind to construct and operate an offshore renewable wind energy project in federal waters off... Issued to Cape Wind Associates, LLC (EPA Permit Number OCS-R1-01) AGENCY: Environmental Protection Agency...

77 FR 50376 - Drawbridge Operation Regulation, Atlantic Intracoastal Waterway (AIWW); Wrightsville Beach, NC...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-21

...; Cape Fear and Northeast Cape Fear River; Wilmington, NC AGENCY: Coast Guard, DHS. ACTION: Final rule... Beach, NC; the Cape Fear Memorial Bridge across the Cape Fear River, mile 26.8; and the Isabel S. Holmes Bridge across the Northeast Cape Fear River, mile 1.0; both in Wilmington, NC. The modification will...

School District Leadership Styles and School Improvement: Evidence from Selected School Principals in the Eastern Cape Province

ERIC Educational Resources Information Center

Moorosi, Pontso; Bantwini, Bongani D.

2016-01-01

The purpose of this study was to investigate how leadership styles in the Eastern Cape school districts support school improvement. Mixed methods research was employed and data was collected through the use of questionnaires and semi-structured interviews with school principals in various districts. The study was guided by the following questions:…

Challenges Pre-School Teachers Face in the Implementation of the Early Childhood Curriculum in the Cape Coast Metropolis

ERIC Educational Resources Information Center

Ntumi, Simon

2016-01-01

The study examined the challenges that pre-school teachers encounter in the implementation of the early childhood curriculum; exploring teaching methods employed by pre-schools teachers in the Cape Coast Metropolis. The study employed descriptive survey as the research design. A convenient sample of 62 pre-school teachers were selected from a…

Promoting sexual and reproductive health among adolescents in southern and eastern Africa (PREPARE): project design and conceptual framework.

PubMed

Aarø, Leif Edvard; Mathews, Catherine; Kaaya, Sylvia; Katahoire, Anne Ruhweza; Onya, Hans; Abraham, Charles; Klepp, Knut-Inge; Wubs, Annegreet; Eggers, Sander Matthijs; de Vries, Hein

2014-01-18

Young people in sub-Saharan Africa are affected by the HIV pandemic to a greater extent than young people elsewhere and effective HIV-preventive intervention programmes are urgently needed. The present article presents the rationale behind an EU-funded research project (PREPARE) examining effects of community-based (school delivered) interventions conducted in four sites in sub-Saharan Africa. One intervention focuses on changing beliefs and cognitions related to sexual practices (Mankweng, Limpopo, South Africa). Another promotes improved parent-offspring communication on sexuality (Kampala, Uganda). Two further interventions are more comprehensive aiming to promote healthy sexual practices. One of these (Western Cape, South Africa) also aims to reduce intimate partner violence while the other (Dar es Salaam, Tanzania) utilises school-based peer education. A modified Intervention Mapping approach is used to develop all programmes. Cluster randomised controlled trials of programmes delivered to school students aged 12-14 will be conducted in each study site. Schools will be randomly allocated (after matching or stratification) to intervention and delayed intervention arms. Baseline surveys at each site are followed by interventions and then by one (Kampala and Limpopo) or two (Western Cape and Dar es Salaam) post-intervention data collections. Questionnaires include questions common for all sites and are partly based on a set of social cognition models previously applied to the study of HIV-preventive behaviours. Data from all sites will be merged in order to compare prevalence and associations across sites on core variables. Power is set to .80 or higher and significance level to .05 or lower in order to detect intervention effects. Intraclass correlations will be estimated from previous surveys carried out at each site. We expect PREPARE interventions to have an impact on hypothesized determinants of risky sexual behaviour and in Western Cape and Dar es Salaam to change sexual practices. Results from PREPARE will (i) identify modifiable cognitions and social processes related to risky sexual behaviour and (ii) identify promising intervention approaches among young adolescents in sub-Saharan cultures and contexts. Controlled Trials ISRCTN56270821 (Cape Town); Controlled Trials ISRCTN10386599 (Limpopo); Clinical Trials NCT01772628 (Kampala); Australian New Zealand Clinical Trials Registry ACTRN12613000900718 (Dar es Salaam).

Promoting sexual and reproductive health among adolescents in southern and eastern Africa (PREPARE): project design and conceptual framework

PubMed Central

2014-01-01

Background Young people in sub-Saharan Africa are affected by the HIV pandemic to a greater extent than young people elsewhere and effective HIV-preventive intervention programmes are urgently needed. The present article presents the rationale behind an EU-funded research project (PREPARE) examining effects of community-based (school delivered) interventions conducted in four sites in sub-Saharan Africa. One intervention focuses on changing beliefs and cognitions related to sexual practices (Mankweng, Limpopo, South Africa). Another promotes improved parent-offspring communication on sexuality (Kampala, Uganda). Two further interventions are more comprehensive aiming to promote healthy sexual practices. One of these (Western Cape, South Africa) also aims to reduce intimate partner violence while the other (Dar es Salaam, Tanzania) utilises school-based peer education. Methods/design A modified Intervention Mapping approach is used to develop all programmes. Cluster randomised controlled trials of programmes delivered to school students aged 12–14 will be conducted in each study site. Schools will be randomly allocated (after matching or stratification) to intervention and delayed intervention arms. Baseline surveys at each site are followed by interventions and then by one (Kampala and Limpopo) or two (Western Cape and Dar es Salaam) post-intervention data collections. Questionnaires include questions common for all sites and are partly based on a set of social cognition models previously applied to the study of HIV-preventive behaviours. Data from all sites will be merged in order to compare prevalence and associations across sites on core variables. Power is set to .80 or higher and significance level to .05 or lower in order to detect intervention effects. Intraclass correlations will be estimated from previous surveys carried out at each site. Discussion We expect PREPARE interventions to have an impact on hypothesized determinants of risky sexual behaviour and in Western Cape and Dar es Salaam to change sexual practices. Results from PREPARE will (i) identify modifiable cognitions and social processes related to risky sexual behaviour and (ii) identify promising intervention approaches among young adolescents in sub-Saharan cultures and contexts. Trial registrations Controlled Trials ISRCTN56270821 (Cape Town); Controlled Trials ISRCTN10386599 (Limpopo); Clinical Trials NCT01772628 (Kampala); Australian New Zealand Clinical Trials Registry ACTRN12613000900718 (Dar es Salaam). PMID:24438582

The first human heart transplant and further advances in cardiac transplantation at Groote Schuur Hospital and the University of Cape Town - with reference to : the operation. A human cardiac transplant : an interim report of a successful operation performed at Groote Schuur Hospital, Cape Town.

PubMed

Brink, J G; Hassoulas, J

2009-01-01

Christiaan (Chris) Barnard was born in 1922 and qualified in medicine at the University of Cape Town in 1946. Following surgical training in South Africa and the USA, Barnard established a successful open-heart surgery programme at Groote Schuur Hospital and the University of Cape Town in 1958. In 1967, he led the team that performed the world's first human-to-human heart transplant. The article describing this remarkable achievement was published in the South African Medical Journal just three weeks after the event and is one of the most cited articles in the cardiovascular field. In the lay media as well, this first transplant remains the most publicised event in world medical history. Although the first heart transplant patient survived only 18 days, four of Groote Schuur Hospital's first 10 patients survived for more than one year, two living for 13 and 23 years, respectively. This relative success amid many failures worldwide did much to generate guarded optimism that heart transplantation would eventually become a viable therapeutic option. This first heart transplant and subsequent ongoing research in cardiac transplantation at the University of Cape Town and in a few other dedicated centres over the subsequent 15 years laid the foundation for heart transplantation to become a well-established form of therapy for end-stage cardiac disease. During this period from 1968 to 1983, Chris Barnard and his team continued to make major contributions to organ transplantation, notably the development of the heterotopic ( 'piggy-back') heart transplants; advancing the concept of brain death, organ donation and other related ethical issues; better preservation and protection of the donor heart (including hypothermic perfusion storage of the heart; studies on the haemodynamic and metabolic effects of brain death; and even early attempts at xenotransplantation.

Bedrock topography of western Cape Cod, Massachusetts, based on bedrock altitudes from geologic borings and analysis of ambient seismic noise by the horizontal-to-vertical spectral-ratio method

USGS Publications Warehouse

Fairchild, Gillian M.; Lane, John W.; Voytek, Emily B.; LeBlanc, Denis R.

2013-01-01

This report presents a topographic map of the bedrock surface beneath western Cape Cod, Massachusetts, that was prepared for use in groundwater-flow models of the Sagamore lens of the Cape Cod aquifer. The bedrock surface of western Cape Cod had been characterized previously through seismic refraction surveys and borings drilled to bedrock. The borings were mostly on and near the Massachusetts Military Reservation (MMR). The bedrock surface was first mapped by Oldale (1969), and mapping was updated in 2006 by the Air Force Center for Environmental Excellence (AFCEE, 2006). This report updates the bedrock-surface map with new data points collected by using a passive seismic technique based on the horizontal-to-vertical spectral ratio (HVSR) of ambient seismic noise (Lane and others, 2008) and from borings drilled to bedrock since the 2006 map was prepared. The HVSR method is based on a relationship between the resonance frequency of ambient seismic noise as measured at land surface and the thickness of the unconsolidated sediments that overlie consolidated bedrock. The HVSR method was shown by Lane and others (2008) to be an effective method for determining sediment thickness on Cape Cod owing to the distinct difference in the acoustic impedance between the sediments and the underlying bedrock. The HVSR data for 164 sites were combined with data from 559 borings to bedrock in the study area to create a spatially distributed dataset that was manually contoured to prepare a topographic map of the bedrock surface. The interpreted bedrock surface generally slopes downward to the southeast as was shown on the earlier maps by Oldale (1969) and AFCEE (2006). The surface also has complex small-scale topography characteristic of a glacially eroded surface. More information about the methods used to prepare the map is given in the pamphlet that accompanies this plate.

Center for the Advancement of Pharmacy Education 2013 Educational Outcomes

PubMed Central

Medina, Melissa S.; Stowe, Cindy D.; Robinson, Evan T.; DeLander, Gary; Beck, Diane E.; Melchert, Russell B.; Supernaw, Robert B.; Roche, Victoria F.; Gleason, Brenda L.; Strong, Mark N.; Bain, Amanda; Meyer, Gerald E.; Dong, Betty J.; Rochon, Jeffrey; Johnston, Patty

2013-01-01

An initiative of the Center for the Advancement of Pharmacy Education (formerly the Center for the Advancement of Pharmaceutical Education) (CAPE), the CAPE Educational Outcomes are intended to be the target toward which the evolving pharmacy curriculum should be aimed. Their development was guided by an advisory panel composed of educators and practitioners nominated for participation by practitioner organizations. CAPE 2013 represents the fourth iteration of the Educational Outcomes, preceded by CAPE 1992, CAPE 1998 and CAPE 2004 respectively. The CAPE 2013 Educational Outcomes were released at the AACP July 2013 Annual meeting and have been revised to include 4 broad domains, 15 subdomains, and example learning objectives. PMID:24159203

33 CFR 334.595 - Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape Canaveral Air Force Station, FL...

Code of Federal Regulations, 2014 CFR

2014-07-01

...; 45th Space Wing, Cape Canaveral Air Force Station, FL; restricted area. 334.595 Section 334.595.... The regulations in this section shall be enforced by the Commander, 45th Space Wing, Patrick Air Force... AND RESTRICTED AREA REGULATIONS § 334.595 Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape...

33 CFR 334.595 - Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape Canaveral Air Force Station, FL...

Code of Federal Regulations, 2013 CFR

2013-07-01

...; 45th Space Wing, Cape Canaveral Air Force Station, FL; restricted area. 334.595 Section 334.595.... The regulations in this section shall be enforced by the Commander, 45th Space Wing, Patrick Air Force... AND RESTRICTED AREA REGULATIONS § 334.595 Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape...

33 CFR 334.595 - Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape Canaveral Air Force Station, FL...

Code of Federal Regulations, 2012 CFR

2012-07-01

...; 45th Space Wing, Cape Canaveral Air Force Station, FL; restricted area. 334.595 Section 334.595.... The regulations in this section shall be enforced by the Commander, 45th Space Wing, Patrick Air Force... AND RESTRICTED AREA REGULATIONS § 334.595 Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape...

33 CFR 334.595 - Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape Canaveral Air Force Station, FL...

Code of Federal Regulations, 2010 CFR

2010-07-01

...; 45th Space Wing, Cape Canaveral Air Force Station, FL; restricted area. 334.595 Section 334.595.... The regulations in this section shall be enforced by the Commander, 45th Space Wing, Patrick Air Force... AND RESTRICTED AREA REGULATIONS § 334.595 Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape...

33 CFR 334.595 - Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape Canaveral Air Force Station, FL...

Code of Federal Regulations, 2011 CFR

2011-07-01

...; 45th Space Wing, Cape Canaveral Air Force Station, FL; restricted area. 334.595 Section 334.595.... The regulations in this section shall be enforced by the Commander, 45th Space Wing, Patrick Air Force... AND RESTRICTED AREA REGULATIONS § 334.595 Atlantic Ocean off Cape Canaveral; 45th Space Wing, Cape...

'Cape capture': Geologic data and modeling results suggest the holocene loss of a Carolina Cape

USGS Publications Warehouse

Thieler, E.R.; Ashton, A.D.

2011-01-01

For more than a century, the origin and evolution of the set of cuspate forelands known as the Carolina Capes-Hatteras, Lookout, Fear, and Romain-off the eastern coast of the United States have been discussed and debated. The consensus conceptual model is not only that these capes existed through much or all of the Holocene transgression, but also that their number has not changed. Here we describe bathymetric, lithologic, seismic, and chronologic data that suggest another cape may have existed between Capes Hatteras and Lookout during the early to middle Holocene. This cape likely formed at the distal end of the Neuse-Tar-Pamlico fiuvial system during the early Holocene transgression, when this portion of the shelf was fiooded ca. 9 cal (calibrated) kyr B.P., and was probably abandoned by ca. 4 cal kyr B.P., when the shoreline attained its present general configuration. Previously proposed mechanisms for cape formation suggest that the large-scale, rhythmic pattern of the Carolina Capes arose from a hydrodynamic template or the preexisting geologic framework. Numerical modeling, however, suggests that the number and spacing of capes can be dynamic, and that a coast can self-organize in response to a high-angle-wave instability in shoreline shape. In shoreline evolution model simulations, smaller cuspate forelands are subsumed by larger neighbors over millennial time scales through a process of 'cape capture.' The suggested former cape in Raleigh Bay represents the first interpreted geological evidence of dynamic abandonment suggested by the self-organization hypothesis. Cape capture may be a widespread process in coastal environments with large-scale rhythmic shoreline features; its preservation in the sedimentary record will vary according to geologic setting, physical processes, and sea-level history. ?? 2011 Geological Society of America.

Learners' Experiences of Learning Support in Selected Western Cape Schools

ERIC Educational Resources Information Center

Bojuwoye, Olaniyi; Moletsane, Mokgadi; Stofile, Sindiswa; Moolla, Nadeen; Sylvester, Fredrick

2014-01-01

The study explored Western Cape primary and secondary school learners' experiences regarding the provision and utilization of support services for improving learning. A qualitative interpretive approach was adopted and data gathered through focus group interviews involving 90 learners. Results revealed that learners received and utilized various…

The Cape Fear Plan.

ERIC Educational Resources Information Center

Conrath, Richard C.

In spring 1992, Cape Fear Community College (CFCC) completed its long-range strategic plan. The consultant who helped guide the institution through the process presented the plan to the Board of Trustees with 60 recommendations for implementation. The Chairman of the Board established task forces to study the recommendations for each major…

Impact of hurricanes on the flux of rainwater and Cape Fear River water dissolved organic carbon to Long Bay, southeastern United States

NASA Astrophysics Data System (ADS)

Avery, G. Brooks; Kieber, Robert J.; Willey, Joan D.; Shank, G. Christopher; Whitehead, Robert F.

2004-09-01

The hurricane flux of rain and river water dissolved organic carbon (DOC) to Long Bay located on the southeastern coast of the United States was determined for four hurricanes that made landfall in the Cape Fear region of North Carolina. Riverine flux of DOC following hurricanes Fran (1996) and Floyd (1999) represented one third and one half of the entire annual river flux of DOC to Long Bay, respectively. The majority of this DOC was recalcitrant and not available for biological consumption. The high flux of DOC from hurricane Floyd resulted from extremely high precipitation amounts (in excess of 50 cm) associated with the hurricane and subsequent flooding. High riverine DOC fluxes were observed following hurricane Fran but not hurricanes Bertha (1996) and Bonnie (1998). The westerly path of Fran deposited rain inland along the Cape Fear River watershed, causing high river flow conditions, while Bonnie and Bertha took an eastern path, resulting in a minimal effect to the Cape Fear River flow rates. The rainwater flux of total DOC to Long Bay from the four hurricanes was not as dramatic as that observed for riverine fluxes. However, unlike river water DOC that is refractory, rainwater DOC is highly labile. Rainwater from the four hurricanes in this study deposited 2-5 times the DOC deposited in an average storm. This represented a flux of 3-9% of the entire annual budget of bioavailable DOC to Long Bay being deposited over a 1 or 2 day period, likely spurring short-term secondary productivity following the hurricanes.

Parental education as an indicator of socioeconomic status: improving quality of data by requiring consistency across measurement occasions.

PubMed

Aarø, Leif Edvard; Flisher, Alan J; Kaaya, Sylvia; Onya, Hans; Namisi, Francis S; Wubs, Annegreet

2009-06-01

Adolescents' reports of parents' education are sometimes used as indicators of socioeconomic status in surveys of health behaviour. The quality of such measurements is questionable. We hypothesized that consistent reporting of parents' education across measurement occasions in prospective panel studies indicates a higher quality of data than single or inconsistent reports. A multi-site, prospective panel study (three measurement occasions) was carried out among adolescents in Cape Town and Mankweng (South Africa), and Dar es Salaam (Tanzania). Analyses were based on data from students participating at baseline and with a valid code for school number (n = 15,684). For Cape Town and Dar es Salaam students, the associations between parents' education and an alternative indicator of socioeconomic status (both measured at baseline) increased with increasing consistency of reports about parents' education across measurement occasions. For Cape Town, the associations of father's education with a range of behavioural and social cognition variables were significantly stronger among ;;consistent'' than among other students. The pattern was the same for mother's education, but with fewer significant interaction effects. Requiring consistency of reports across data-collection occasions may, under the right combination of circumstances, make a difference. Insignificant and "close to zero'' associations may turn out to be at least moderately strong and statistically significant. When applying indicators of socioeconomic status, such as parents' highest level of completed education, it is most advantageous to use data from prospective panel studies, and to check for consistency of answers across measurement occasions.

Mobile HIV screening in Cape Town, South Africa: clinical impact, cost and cost-effectiveness.

PubMed

Bassett, Ingrid V; Govindasamy, Darshini; Erlwanger, Alison S; Hyle, Emily P; Kranzer, Katharina; van Schaik, Nienke; Noubary, Farzad; Paltiel, A David; Wood, Robin; Walensky, Rochelle P; Losina, Elena; Bekker, Linda-Gail; Freedberg, Kenneth A

2014-01-01

Mobile HIV screening may facilitate early HIV diagnosis. Our objective was to examine the cost-effectiveness of adding a mobile screening unit to current medical facility-based HIV testing in Cape Town, South Africa. We used the Cost Effectiveness of Preventing AIDS Complications International (CEPAC-I) computer simulation model to evaluate two HIV screening strategies in Cape Town: 1) medical facility-based testing (the current standard of care) and 2) addition of a mobile HIV-testing unit intervention in the same community. Baseline input parameters were derived from a Cape Town-based mobile unit that tested 18,870 individuals over 2 years: prevalence of previously undiagnosed HIV (6.6%), mean CD4 count at diagnosis (males 423/µL, females 516/µL), CD4 count-dependent linkage to care rates (males 31%-58%, females 49%-58%), mobile unit intervention cost (includes acquisition, operation and HIV test costs, $29.30 per negative result and $31.30 per positive result). We conducted extensive sensitivity analyses to evaluate input uncertainty. Model outcomes included site of HIV diagnosis, life expectancy, medical costs, and the incremental cost-effectiveness ratio (ICER) of the intervention compared to medical facility-based testing. We considered the intervention to be "very cost-effective" when the ICER was less than South Africa's annual per capita Gross Domestic Product (GDP) ($8,200 in 2012). We projected that, with medical facility-based testing, the discounted (undiscounted) HIV-infected population life expectancy was 132.2 (197.7) months; this increased to 140.7 (211.7) months with the addition of the mobile unit. The ICER for the mobile unit was $2,400/year of life saved (YLS). Results were most sensitive to the previously undiagnosed HIV prevalence, linkage to care rates, and frequency of HIV testing at medical facilities. The addition of mobile HIV screening to current testing programs can improve survival and be very cost-effective in South Africa and other resource-limited settings, and should be a priority.

Soil and water conservation strategies and impact on sustainable livelihood in Cape Verde - Case study of Ribeira Seca watershed

NASA Astrophysics Data System (ADS)

Baptista, I.; Ferreira, A. D.; Tavares, J.; Querido, A. L. E.; Reis, A. E. A.; Geissen, V.; Ritsema, C.; Varela, A.

2012-04-01

Cape Verde, located off the coast of Senegal in western Africa, is a volcanic archipelago where a combination of human, climatic, geomorphologic and pedologic factors has led to extensive degradation of the soils. Like other Sahelian countries, Cape Verde has suffered the effects of desertification through the years, threatening the livelihood of the islands population and its fragile environment. In fact, the steep slopes in the ore agricultural islands, together with semi-arid and arid environments, characterized by an irregular and poorly distributed rainy season, with high intensity rainfall events, make dryland production a challenge. To survive in these fragile conditions, the stabilization of the farming systems and the maintenance of sustainable yields have become absolute priorities, making the islands an erosion control laboratory. Soil and water conservation strategies have been a centerpiece of the government's agricultural policies for the last half century. Aiming to maintain the soil in place and the water inside the soil, the successive governments of Cape Verde have implemented a number of soil and water conservation techniques, the most common ones being terraces, half moons, live barriers, contour rock walls, contour furrows and microcatchments, check dams and reforestation with drought resistant species. The soil and water conservation techniques implemented have contributed to the improvement of the economical and environmental conditions of the treated landscape, making crop production possible, consequently, improving the livelihood of the people living on the islands. In this paper, we survey the existing soil and water conservation techniques, analyze their impact on the livelihood condition of the population through a thorough literature review and field monitoring using a semi-quantitative methodology and evaluate their effectiveness and impact on crop yield in the Ribeira Seca watershed. A brief discussion is given on the cost and effectiveness of the techniques to reduce soil erosion and to promote rainfall infiltration. Finally, we discuss the critical governance factors that lead to the successful implementation of such strategy in a country with scarce natural resources.

Using Exploratory Talk to Enhance Problem-Solving and Reasoning Skills in Grade-7 Science Classrooms

ERIC Educational Resources Information Center

Webb, Paul; Treagust, David F.

2006-01-01

This study investigates whether the generation of exploratory talk in grade seven, second-language science classrooms in the Eastern Cape Province, South Africa, has a positive effect on learners in terms of their problem-solving and reasoning skills and whether socio-cultural "milieus" (urban, peri-urban and rural settings of schools)…

Demographic Profiling--A Determination of Academic Performance in a Postgraduate Diploma in Marketing Management

ERIC Educational Resources Information Center

Beneke, J.; Beeming, C.

2011-01-01

This article analyses the direct effect of demographic variables on academic outcomes. The study concludes that ethnic group plays a pivotal role in determining the academic performance of students registered for the Postgraduate Diploma in Marketing Management at the University of Cape Town. White students (presumed to emanate from a privileged…

Stress and Coping Strategies among Distance Education Students at the University of Cape Coast, Ghana

ERIC Educational Resources Information Center

Kwaah, Christopher Yaw; Essilfie, Gabriel

2017-01-01

This study was designed to identify the causes of stress and coping strategies adopted among distance education students at the College of Distance Education in the University of Cape Coast. A total of 332 diploma and post-diploma final year students in 2014/2015 academic year were selected from two study centers using random sampling procedure to…

Cape Cod Transit Task Force : Five-Year Public Transportation Plan

DOT National Transportation Integrated Search

2002-06-30

The U.S. Department of Transportation's Volpe National Transportation Systems : Center has been working in cooperation with the Cape Cod Regional Transit : Authority, the Cape Cod Commission, and other organizations participating on : the Cape Cod Tr...

The 2006 Cape Canaveral Air Force Station Range Reference Atmosphere Model Validation Study and Sensitivity Analysis to the National Aeronautics and Space Administration's Space Shuttle

NASA Technical Reports Server (NTRS)

Decker, Ryan K.; Burns, Lee; Merry, Carl; Harrington, Brian

2008-01-01

Atmospheric parameters are essential in assessing the flight performance of aerospace vehicles. The effects of the Earth's atmosphere on aerospace vehicles influence various aspects of the vehicle during ascent ranging from its flight trajectory to the structural dynamics and aerodynamic heatmg on the vehicle. Atmospheric databases charactenzing the wind and thermodynamic environments, known as Range Reference Atmospheres (RRA), have been developed at space launch ranges by a governmental interagency working group for use by aerospace vehicle programs. The National Aeronantics and Space Administration's (NASA) Space Shuttle Program (SSP), which launches from Kennedy Space Center, utilizes atmosphenc statistics derived from the Cape Canaveral Air Force Station Range Reference Atmosphere (CCAFS RRA) database to evaluate environmental constraints on various aspects of the vehlcle during ascent.

46 CFR 7.60 - Cape Fear, NC to Sullivans Island, SC.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Cape Fear, NC to Sullivans Island, SC. 7.60 Section 7.60... Atlantic Coast § 7.60 Cape Fear, NC to Sullivans Island, SC. (a) A line drawn from the southernmost extremity to Cape Fear to latitude 33°49.5′ N. longitude 78°03.7′ W. (Cape Fear River Entrance Lighted Bell...

Particle-tracking analysis of contributing areas of public-supply wells in simple and complex flow systems, Cape Cod, Massachusetts

USGS Publications Warehouse

Barlow, Paul M.

1997-01-01

Steady-state, two- and three-dimensional, ground-water-flow models coupled with particle tracking were evaluated to determine their effectiveness in delineating contributing areas of wells pumping from stratified-drift aquifers of Cape Cod, Massachusetts. Several contributing areas delineated by use of the three-dimensional models do not conform to simple ellipsoidal shapes that are typically delineated by use of two-dimensional analytical and numerical modeling techniques and included discontinuous areas of the water table.

Aerosol Effects on Microphysical Processes, Storm Structure, and Cold Pool Strength in Simulated Supercell Thunderstorms from VORTEX-2 and VORTEX-SE

NASA Astrophysics Data System (ADS)

Guo, M.; Dawson, D. T., II; Baldwin, M. E.; Mansell, E. R.

2017-12-01

The cloud condensation nuclei (CCN) concentration has been found to strongly affect microphysical, dynamical and thermodynamical processes in supercells and other deep convective storms. Moreover, recent simulation studies have shown aerosols effects differ between higher- and lower-CAPE environments. Owing to the known sensitivity of severe storms to microphysical differences, studying the impact of aerosols supercell storms different environments is of clear societal importance. Tornadic environments in the southwastern U.S. are generally characterized by lower magnitudes CAPE and deeper tropospheric moisture than those in the Great Plains. These two regions were the focus of Verification of the Origins of Rotation in Tornadoes Experiment (VORTEX)-2 and VORTEX-Southeast (SE) field campaigns, respectively. In our study, we simulate several cases from VORTEX-2 and -SE with the Advanced Regional Prediction System (ARPS) Model at 6 different CCN concentrations (100-3000 cm-3). We use NSSL 3-moment microphysics parameterization schemeto explicitly predict precipitation particle size distributions and microphysirocess rates. Overall, storms under the higher-CAPE VORTEX-2 environments are more sensitiveto the change of CCN than those under the lower-CAPE VORTEX-SE environments. Updraft volume decreases as CCN increases for the VORTEX-2 cases, whereas the opposite is true but with a much weaker trend for the VORTEX-SE cases. Moreover, the cold pool strength drops dramatically as CCN surpasses 1000 cm-3n the VORTEX-2 cases but barely changes for the VORTEX-SE cases. Through a microphysics budget analysis, we show the change of the importance of ice processes is key to the differing sensitivities. in the VORTEX-2 cases, deposition to ice nuclei, cloud drop freezing and rain drop freezing in the upper levels (5-11km) contribute more to latent heating since more rain and cloud drops are lifted above the freezing level due to stronger updrafts. For CCN concentration over 1000cm-3, the drops become too small for efficient accretion by graupel and hail, leading to considerable decrease of latent heating and thus updraft volume. Finally, the decrease in cold pool strength in the VORTEX-2 cases at higher CCN is due to the rapid decrease of graupel melting at lower levels (<2km).

Dynamics of Indian Ocean Slavery Revealed through Isotopic Data from the Colonial Era Cobern Street Burial Site, Cape Town, South Africa (1750-1827)

PubMed Central

Morris, Alan G.; Kars, Henk; Davies, Gareth R.

2016-01-01

The Dutch East India Company (VOC) intended the Cape of Good Hope to be a refreshment stop for ships travelling between the Netherlands and its eastern colonies. The indigenous Khoisan, however, did not constitute an adequate workforce, therefore the VOC imported slaves from East Africa, Madagascar and Asia to expand the workforce. Cape Town became a cosmopolitan settlement with different categories of people, amongst them a non-European underclass that consisted of slaves, exiles, convicts and free-blacks. This study integrated new strontium isotope data with carbon and nitrogen isotope results from an 18th-19th century burial ground at Cobern Street, Cape Town, to identify non-European forced migrants to the Cape. The aim of the study was to elucidate individual mobility patterns, the age at which the forced migration took place and, if possible, geographical provenance. Using three proxies, 87Sr/86Sr, δ13Cdentine and the presence of dental modifications, a majority (54.5%) of the individuals were found to be born non-locally. In addition, the 87Sr/86Sr data suggested that the non-locally born men came from more diverse geographic origins than the migrant women. Possible provenances were suggested for two individuals. These results contribute to an improved understanding of the dynamics of slave trading in the Indian Ocean world. PMID:27309532

Dynamics of Indian Ocean Slavery Revealed through Isotopic Data from the Colonial Era Cobern Street Burial Site, Cape Town, South Africa (1750-1827).

PubMed

Kootker, Lisette M; Mbeki, Linda; Morris, Alan G; Kars, Henk; Davies, Gareth R

2016-01-01

The Dutch East India Company (VOC) intended the Cape of Good Hope to be a refreshment stop for ships travelling between the Netherlands and its eastern colonies. The indigenous Khoisan, however, did not constitute an adequate workforce, therefore the VOC imported slaves from East Africa, Madagascar and Asia to expand the workforce. Cape Town became a cosmopolitan settlement with different categories of people, amongst them a non-European underclass that consisted of slaves, exiles, convicts and free-blacks. This study integrated new strontium isotope data with carbon and nitrogen isotope results from an 18th-19th century burial ground at Cobern Street, Cape Town, to identify non-European forced migrants to the Cape. The aim of the study was to elucidate individual mobility patterns, the age at which the forced migration took place and, if possible, geographical provenance. Using three proxies, 87Sr/86Sr, δ13Cdentine and the presence of dental modifications, a majority (54.5%) of the individuals were found to be born non-locally. In addition, the 87Sr/86Sr data suggested that the non-locally born men came from more diverse geographic origins than the migrant women. Possible provenances were suggested for two individuals. These results contribute to an improved understanding of the dynamics of slave trading in the Indian Ocean world.

COASTAL CONDITIONS IN THE VIRGINIAN PROVINCE (CAPE COD TO CAPE HENRY)

EPA Science Inventory

The U.S. EPA Environmental Monitoring and Assessment Program (EMAP) collected ecological condition data during 1990 through 1993 from the estuarine waters of the Virginian Biogeographic Province (Cape Henry to Cape Cod) to answer broad-scale questions on environmental conditions...

Establishing Validity of the Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V)

ERIC Educational Resources Information Center

Zraick, Richard I.; Kempster, Gail B.; Connor, Nadine P.; Thibeault, Susan; Klaben, Bernice K.; Bursac, Zoran; Thrush, Carol R.; Glaze, Leslie E.

2011-01-01

Purpose: The Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) was developed to provide a protocol and form for clinicians to use when assessing the voice quality of adults with voice disorders (Kempster, Gerratt, Verdolini Abbott, Barkmeier-Kramer, & Hillman, 2009). This study examined the reliability and the empirical validity of the…

Cape Verdean Immigrants' Career Development and School Engagement: Perceived Discrimination as a Moderator

ERIC Educational Resources Information Center

Coutinho, Maria Teresa; Blustein, David L.

2014-01-01

This study examined the contribution of perceptions of discrimination, career planning, and vocational identity to the school engagement experiences of first- and second-generation immigrants among a sample of 125 Cape Verdean high school students. Perceived ethnic discrimination was found to moderate the association between both vocational…

Arctic Security: An Adaptive Approach for a Changing Climate

DTIC Science & Technology

2009-04-01

Hansen, Director of NASA Goddard Institute for Space Studies and Adjunct Professor of Earth and Environmental Sciences at Columbia University’s Earth...realized by megaships which are too large to use the Panama and Suez Canals and are currently making the long treks around the Cape of Good Hope and Cape

Parental Investment, Club Membership, and Youth Sexual Risk Behavior in Cape Town

ERIC Educational Resources Information Center

Camlin, Carol S.; Snow, Rachel C.

2008-01-01

This study examines whether parental investment and membership in social clubs are associated with safer sexual behaviors among South African youth. Participants comprised 4,800 randomly selected adolescents age 14 to 22 living in the Cape Town area in 2002. Logistic regression was used to examine associations between measures of parental…

Improving Access to Pediatric Cardiology in Cape Verde via a Collaborative International Telemedicine Service.

PubMed

Lapão, Luís Velez; Correia, Artur

2015-01-01

This paper addresses the role of international telemedicine services in supporting the evacuation procedures from Cape Verde to Portugal, enabling better quality and cost reductions in the management of the global health system. The Cape Verde, as other African countries, health system lacks many medical specialists, like pediatric cardiologists, neurosurgery, etc. In this study, tele-cardiology shows good results as diagnostic support to the evacuation decision. Telemedicine services show benefits while monitoring patients in post-evacuation, helping to address the lack of responsive care in some specialties whose actual use will help save resources both in provision and in management of the evacuation procedures. Additionally, with tele-cardiology collaborative service many evacuations can be avoided whereas many cases will be treated and followed locally in Cape Verde with remote technical support from Portugal. This international telemedicine service enabled more efficient evacuations, by reducing expenses in travel and housing, and therefore contributed to the health system's improvement. This study provides some evidence of how important telemedicine really is to cope with both the geography and the shortage of physicians.

Characterization of polyphenol oxidase from Cape gooseberry (Physalis peruviana L.) fruit.

PubMed

Bravo, Karent; Osorio, Edison

2016-04-15

Cape gooseberry (Physalis peruviana) is an exotic fruit highly valued, however it is a very rich source of polyphenol oxidase (PPO). In this study, Cape gooseberry PPO was isolated and biochemically characterized. The enzyme was extracted and purified using acetone and aqueous two-phase systems. The data indicated that PPO had the highest substrate affinity for chlorogenic acid, 4-methylcatechol and catechol. Chlorogenic acid was the most suitable substrate (Km=0.56±0.07 mM and Vmax=53.15±2.03 UPPO mL(-1) min(-1)). The optimal pH values were 5.5 for catechol and 4-methylcatechol and 5.0 for chlorogenic acid. Optimal temperatures were 40°C for catechol, 25°C for 4-methylcatechol and 20°C for chlorogenic acid. In inhibition tests, the most potent inhibitor was found to be ascorbic acid followed by L-cysteine and quercetin. This study shows possible treatments that can be implemented during the processing of Cape gooseberry fruits to prevent browning. Copyright © 2015 Elsevier Ltd. All rights reserved.

‘Cape capture’: Geologic data and modeling results suggest the Holocene loss of a Carolina Cape

USGS Publications Warehouse

Thieler, E. Robert; Ashton, Andrew D.

2011-01-01

For more than a century, the origin and evolution of the set of cuspate forelands known as the Carolina Capes—Hatteras, Lookout, Fear, and Romain—off the eastern coast of the United States have been discussed and debated. The consensus conceptual model is not only that these capes existed through much or all of the Holocene transgression, but also that their number has not changed. Here we describe bathymetric, lithologic, seismic, and chronologic data that suggest another cape may have existed between Capes Hatteras and Lookout during the early to middle Holocene. This cape likely formed at the distal end of the Neuse-Tar-Pamlico fluvial system during the early Holocene transgression, when this portion of the shelf was flooded ca. 9 cal (calibrated) kyr B.P., and was probably abandoned by ca. 4 cal kyr B.P., when the shoreline attained its present general configuration. Previously proposed mechanisms for cape formation suggest that the large-scale, rhythmic pattern of the Carolina Capes arose from a hydrodynamic template or the preexisting geologic framework. Numerical modeling, however, suggests that the number and spacing of capes can be dynamic, and that a coast can self-organize in response to a high-angle-wave instability in shoreline shape. In shoreline evolution model simulations, smaller cuspate forelands are subsumed by larger neighbors over millennial time scales through a process of ‘cape capture.’ The suggested former cape in Raleigh Bay represents the first interpreted geological evidence of dynamic abandonment suggested by the self-organization hypothesis. Cape capture may be a widespread process in coastal environments with large-scale rhythmic shoreline features; its preservation in the sedimentary record will vary according to geologic setting, physical processes, and sea-level history.

Outlook. Number 364

ERIC Educational Resources Information Center

Council for American Private Education, 2011

2011-01-01

Council for American Private Education (CAPE) is a coalition of national associations serving private schools K-12. "Outlook" is published monthly by CAPE. This issue contains the following articles: (1) House Approves Opportunity Scholarships Bill; (2) Lawmakers Discuss Key Issues at CAPE Forum; (3) Digital Now; and (4) CAPE Notes.

Questioning the Pace and Pathway of E-Government Development in Africa: A Case Study of South Africa's Cape Gateway Project

ERIC Educational Resources Information Center

Maumbe, Blessing Mukabeta; Owei, Vesper; Alexander, Helen

2008-01-01

The paper examines e-government development in Africa. This study is based on the Cape Gateway project in South Africa, a leading e-government initiative on the continent. We observe that African countries have jumped on the e-government band wagon by looking mostly at the benefits without a clear risk assessment. We argue that African countries…

Substance Use and Psychosocial Predictors of High School Dropout in Cape Town, South Africa

ERIC Educational Resources Information Center

Flisher, Alan J.; Townsend, Loraine; Chikobvu, Perpetual; Lombard, Carl F.; King, Gary

2010-01-01

The aims of this study were to examine whether use of tobacco, alcohol, and illicit drugs predicts dropout among secondary school students in Cape Town, South Africa. A self-report instrument was administered to 1,470 Grade 8 students. The proportion of students that dropped out of school between the onset of the study and 4 years later was 54.9%.…

The South African Food Sensitisation and Food Allergy population-based study of IgE-mediated food allergy: validity, safety, and acceptability.

PubMed

Basera, Wisdom; Botha, Maresa; Gray, Claudia L; Lunjani, Nonhlanhla; Watkins, Alexandra S M; Venter, Carina; Allen, Katrina J; Hlela, Carol; Zar, Heather J; Levin, Michael E

2015-08-01

Few studies exist on food sensitization and challenge-proven food allergy in low- and middle-income countries. To describe the study design and methodology to recruit infants from an African population for skin prick testing and oral food challenges and the use of preliminary data to investigate the extent to which the study sample is representative of the target population. Children 12 to 36 months old were recruited from childcare education facilities in Cape Town. Children underwent skin prick testing to foods. Those with a reactive wheal of at least 1 mm larger than the negative control and not clearly tolerant according to history to a full age-appropriate portion to at least 1 food underwent oral food challenges. Parents who chose not to participate completed a nonparticipant questionnaire. Interim analysis of at least 500 respondents was performed. Demographic features of participating children were compared with those of nonparticipants and the population demographics of the most recent Cape Town census data. The response rate was 60.1%, with high participation and completion rates of 96.5% and 97.5%, respectively. Demographics of the completed participant sample were similar to those of the Cape Town census. Use of a nonrespondent questionnaire indicated no selection bias in favor of increased participation of participants with allergy. No ethnic differences in sensitization or food allergy were evident. The study was safe and feasible and the recruitment was effective and representative of the target population. Future studies will aim to increase the precision of the prevalence of food sensitization and allergy, describe environmental risk factors, and include a rural black African cohort. Copyright © 2015 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

77 FR 26048 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

...--Cape Adare; ASPA 160--Cape Geology; and, ASPA 171--Narebski Point. Access to these sites will be on an... Shirreff; ASPA 150--Ardley Island; ASPA 158--Cape Adare; ASPA 160--Cape Geology; and, ASPA 171-- Narebski...

Development and application of damage assessment modeling: example assessment for the North Cape oil spill.

PubMed

McCay, Deborah French

2003-01-01

Natural resource damage assessment (NRDA) models for oil spills have been under development since 1984. Generally applicable (simplified) versions with built-in data sets are included in US government regulations for NRDAs in US waters. The most recent version of these models is SIMAP (Spill Impact Model Application Package), which contains oil fates and effects models that may be applied to any spill event and location in marine or freshwater environments. It is often not cost-effective or even possible to quantify spill impacts using field data collections. Modeling allows quantification of spill impacts using as much site-specific data as available, either as input or as validation of model results. SIMAP was used for the North Cape oil spill in Rhode Island (USA) in January 1996, for injury quantification in the first and largest NRDA case to be performed under the 1996 Oil Pollution Act NRDA regulations. The case was successfully settled in 1999. This paper, which contains a description of the model and application to the North Cape spill, delineates and demonstrates the approach.

Triggering mechanism and tsunamogenic potential of the Cape Fear Slide complex, U.S. Atlantic margin

USGS Publications Warehouse

Hornbach, Matthew J.; Lavier, Luc L.; Ruppel, Carolyn D.

2007-01-01

Analysis of new multibeam bathymetry data and seismic Chirp data acquired over the Cape Fear Slide complex on the U.S. Atlantic margin suggests that at least 5 major submarine slides have likely occurred there within the past 30,000 years, indicating that repetitive, large-scale mass wasting and associated tsunamis may be more common in this area than previously believed. Gas hydrate deposits and associated free gas as well as salt tectonics have been implicated in previous studies as triggers for the major Cape Fear slide events. Analysis of the interaction of the gas hydrate phase boundary and the various generations of slides indicates that only the most landward slide likely intersected the phase boundary and inferred high gas pressures below it. For much of the region, we believe that displacement along a newly recognized normal fault led to upward migration of salt, oversteepening of slopes, and repeated slope failures. Using new constraints on slide morphology, we develop the first tsunami model for the Cape Fear Slide complex. Our results indicate that if the most seaward Cape Fear slide event occurred today, it could produce waves in excess of 2 m at the present-day 100 m bathymetric contour.

Strategic Analysis for the MER Cape Verde Approach

NASA Technical Reports Server (NTRS)

Gaines, Daniel; Belluta, Paolo; Herman, Jennifer; Hwang, Pauline; Mukai, Ryan; Porter, Dan; Jones, Byron; Wood, Eric; Grotzinger, John; Edgar, Lauren;

Influence of cultivar and ripening time on bioactive compounds and antioxidant properties in Cape gooseberry (Physalis peruviana L.).

PubMed

Bravo, Karent; Sepulveda-Ortega, Stella; Lara-Guzman, Oscar; Navas-Arboleda, Alejandro A; Osorio, Edison

2015-05-01

Cape gooseberry (Physalis peruviana) is an exotic fruit highly valued for its organoleptic properties and bioactive compounds. Considering that the presence of phenolics and ascorbic acid could contribute to its functional capacity, it is important to investigate the quality parameters, bioactive contents and functional properties with respect to genotype and ripening time. In this study the genotype effect was evaluated in 15 cultivars for two different harvest times. Changes during maturation were recorded in two commercial cultivars within seven levels of maturity. Multivariate statistical analysis suggested that phenolic content and ORAC value were mainly affected by harvest time and that ascorbic acid content and DPPH level were mainly affected by genotype. In addition, acidity, phenolic content, ORAC value and inhibition of LDL oxidation decreased with maturity, but soluble solids content, ascorbic acid content, β-carotene content and DPPH-scavenging activity were higher in mature fruits. The phenolic content, ascorbic acid content and antioxidant properties of Cape gooseberry fruit were strongly affected by cultivar, harvest time and maturity state. Consequently, the harvest time must be scheduled carefully to gain the highest proportion of bioactive compounds according to the specific cultivar and the environment where it is grown. © 2014 Society of Chemical Industry.

Cape Cod, MA, USA

NASA Technical Reports Server (NTRS)

1992-01-01

Cape Cod, (41.5N, 71.0W) is a very young geological feature, formed after the retreat of the last glaciers some 15,000 years ago. The cape is made up of outwash sands laid down by rivers of melt water from glaciers which pushed as far south as Long Island. The cape itself then lay many miles inland but as the glaciers melted, the water level of the world's oceans rose to their present level. Storm waves, wind and tides then formed the Cape Cod hook.

75 FR 56093 - FFP Mass 1, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-15

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13828-000] FFP Mass 1, LLC... study the feasibility of the Cape Cod Tidal Energy Project to be located in the Cape Cod Canal and a...,000 hydrokinetic tidal devices consisting of a turbine blade assembly and an integrated 10-kilowatt...

Cape Blanco Wind Farm Feasibility Study : Technical Report, No. 2, Civil Engineering.

DOE Office of Scientific and Technical Information (OSTI.GOV)

United States. Bonneville Power Administration.

1986-09-01

An investigation of the feasibility of developing a wind farm near Cape Blanco, Oregon, requires a plan for civil engineering and preliminary site construction activities. In this report, plans for such activities and related cost estimates are presented for a wind farm using either a Boeing MOD-2 or FloWind 170 wind turbine generator.

Career Decision Making in the Shadow of Economic Downturn: A Study of Cape Breton High School Students.

ERIC Educational Resources Information Center

Chisholm, Joe; Edmunds, Alan

2001-01-01

Examines differences in levels of career decision-making self-efficacy in Cape Breton high school students who lived in communities with recent closures of mining and steel industries compared to students from communities with no such closures. Students demonstrated considerable confidence in their career decision-making abilities implying that…

Influence of ocean surface conditions on atmospheric vertical thermodynamic structure and deep convection

NASA Technical Reports Server (NTRS)

Fu, Rong; Del Genio, Anthony D.; Rossow, William B.

1994-01-01

The authors analyze the influence of Sea Surface Temperature (SST) and surface wind divergence on atmospheric thermodynamic structure and the resulting effects on the occurrence of deep convection using National Meteorological Center radiosonde data and International Satellite Cloud Climatology Program data for July 1983-July 1985. The onset of deep convection requires not only the existence of positive convective available potential energy (CAPE), but also an unstable planetary boundary layer (PBL). A stable PBL is observed to suppress deep convection even when CAPE is positive. Variations of SST have a major effect on CAPE, but surface wind divergence can also affect deep convection by changing the lapse rate in the lower troposphere and humidity in the PBL. Specifically, when SST is greater than or equal to 28 C, CAPE is always positive, and surface wind divergence does not qualitatively change the buoyancy profile above the PBL. Strong surface wind divergence, however, stabilizes the PBL so as to suppress the initiation of deep convection. In warm SST regions, CAPE is greater than 0 regardless of assumptions about condensate loading, although the pseudoadiabatic limit is more consistent with the observed deep convection than the reversible moist-adiabatic limit under these circumstances. When SST is less than 27 C, CAPE is usually negative and inhibits convection, but strong surface wind convergence can destabilize the inversion layer and moisten the PBL enough to make the atmosphere neutrally stable in the mean. As a result, deep convection is generally enhanced either when SST is greater than or equal to 28 C in the absence of strong surface wind divergence or when strong surface wind convergence occurs even if SST is less than 27 C. The anomalous suppression of deep convection in the warm area of the equatorial west Pacific lying between the intertropical convergence zone (ITCZ) and south Pacific convergence zone (SPCZ) is probably caused by dryness in the PBL and an inversion in that area. The seasonal cycles of deep convection and surface wind divergence are in phase with the maximum solar radiation and lead SST for one to three months in the central Pacific. The change of PBL relative humidity plays a critical role in the changeover to convective instability in this case. The seasonal change of deep convection and associated clouds seems not to have important effects on the seasonal change of local SST in the central Pacific.

77 FR 9699 - Cape Cod National Seashore Advisory Commission; Cape Cod National Seashore, South Wellfleet, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-17

... DEPARTMENT OF THE INTERIOR National Park Service [1730-SZM] Cape Cod National Seashore Advisory Commission; Cape Cod National Seashore, South Wellfleet, MA AGENCY: National Park Service, Interior. ACTION... National Seashore, 99 Marconi Site Road, Wellfleet, MA 02667. Date: February 7, 2012. George E. Price, Jr...

77 FR 22611 - Cape Cod National Seashore Advisory Commission; Cape Cod National Seashore, South Wellfleet, MA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-16

... DEPARTMENT OF THE INTERIOR National Park Service [1730-SZM] Cape Cod National Seashore Advisory Commission; Cape Cod National Seashore, South Wellfleet, MA AGENCY: National Park Service, Interior. ACTION... Cod National Seashore, 99 Marconi Site Road, Wellfleet, MA 02667. Dated: April 9, 2012. George E...

33 CFR 80.105 - Calais, ME to Cape Small, ME.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Calais, ME to Cape Small, ME. 80... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.105 Calais, ME to Cape Small, ME... International Bridge at Calais, ME to the southwesternmost extremity of Bald Head at Cape Small. ...

33 CFR 80.105 - Calais, ME to Cape Small, ME.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Calais, ME to Cape Small, ME. 80... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.105 Calais, ME to Cape Small, ME... International Bridge at Calais, ME to the southwesternmost extremity of Bald Head at Cape Small. ...

33 CFR 80.105 - Calais, ME to Cape Small, ME.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Calais, ME to Cape Small, ME. 80... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.105 Calais, ME to Cape Small, ME... International Bridge at Calais, ME to the southwesternmost extremity of Bald Head at Cape Small. ...

33 CFR 80.105 - Calais, ME to Cape Small, ME.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Calais, ME to Cape Small, ME. 80... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.105 Calais, ME to Cape Small, ME... International Bridge at Calais, ME to the southwesternmost extremity of Bald Head at Cape Small. ...

Nho Lobo: Folk Tales of the Cape Verdean People. Teacher's Guide.

ERIC Educational Resources Information Center

Nyhan, Patricia; Almeida, Raymond A.

The teacher's guide presents two Cape Verdean folktales, background information, discussion questions, and activity suggestions for grades 4-6. The objective is to teach students about Cape Verde and its culture through folklore. The guide contains five sections. Section I offers a description of Cape Verdean folklore, describes five ways folklore…

76 FR 11960 - Drawbridge Operation Regulation; Cape Fear River, Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-04

... Operation Regulation; Cape Fear River, Wilmington, NC AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulation governing the operation of the Cape Fear River Memorial Bridge, across the Cape Fear River, mile 26.8, at Wilmington, NC. The deviation restricts the operation of the draw span...

75 FR 44916 - Drawbridge Operation Regulation; Cape Fear River, Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-30

... Operation Regulation; Cape Fear River, Wilmington, NC AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulation governing the operation of the Cape Fear River Memorial Bridge, across the Cape Fear River, mile 26.8, at Wilmington, NC. The deviation restricts the operation of the draw span...

77 FR 12475 - Drawbridge Operation Regulations; Cape Fear River, Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-01

... Operation Regulations; Cape Fear River, Wilmington, NC AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulations governing the operation of the Cape Fear Memorial Bridge, across the Cape Fear River, mile 26.8, at Wilmington, NC. The deviation restricts the operation of the draw span to...

76 FR 53342 - Drawbridge Operation Regulations; Cape Fear River, Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

... Operation Regulations; Cape Fear River, Wilmington, NC AGENCY: Coast Guard, DHS. ACTION: Notice of temporary... deviation from the regulations governing the operation of the Cape Fear Memorial Bridge, at mile 26.8, over Cape Fear River, at Wilmington, NC. The deviation restricts the operation of the draw span to...

33 CFR 117.823 - Cape Fear River.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cape Fear River. 117.823 Section... DRAWBRIDGE OPERATION REGULATIONS Specific Requirements North Carolina § 117.823 Cape Fear River. The draw of the Cape Fear Memorial Bridge, mile 26.8, at Wilmington need not open for the passage of vessel from 8...

Effects of simulated ground-water pumping and recharge on ground-water flow in Cape Cod, Martha's Vineyard, and Nantucket Island basins, Massachusetts

USGS Publications Warehouse

Masterson, John P.; Barlow, Paul M.

1997-01-01

Three-dimensional transient ground-water-flow models that simulate both freshwater and saltwater flow were developed for the flow cells of the Cape Cod Basin to determine the effects of long-term pumping and recharge, seasonal fluctuations in pumping and recharge, and prolonged reductions of natural recharge, on the position of the freshwater-saltwater interface, water-table and pond altitudes, and streamflow and discharge to coastal marshes and embayments. Two-dimensional, finite-difference change models were developed for Martha's Vineyard and Nantucket Island basins to determine anticipated drawdowns in response to projected summer season pumping rates for 180 days of no recharge.

Antibiotic prescribing practice and adherence to guidelines in primary care in the Cape Town Metro District, South Africa.

PubMed

Gasson, J; Blockman, M; Willems, B

2018-03-28

Knowledge of antibiotic prescribing practice in primary care in South Africa is limited. As 80% of human antibiotic use is in primary care, this knowledge is important in view of the global problem of antibiotic resistance. To assess antibiotic prescribing in primary care facilities in the Cape Town Metro District and compare it with current national guidelines, and to assess the reasons why prescriptions were not adherent to guidelines. A retrospective medical record review was performed in April/May 2016. Records of all patients seen over 2 days in each of eight representative primary care facilities in the Cape Town Metro District were reviewed. The treatment of any patient who raised a new complaint on either of those days was recorded. Prophylactic antibiotic courses, tuberculosis treatment and patients with a non-infection diagnosis were excluded. Treatment was compared with the Standard Treatment Guidelines and Essential Medicines List for South Africa, Primary Healthcare Level, 2014 edition. Of 654 records included, 68.7% indicated that an antibiotic had been prescribed. Overall guideline adherence was 45.1%. Adherence differed significantly between facilities and according to the physiological system being treated, whether the prescription was for an adult or paediatric patient, and the antibiotic prescribed. Healthcare professional type and patient gender had no significant effect on adherence. The main reasons for non-adherence were an undocumented diagnosis (30.5%), antibiotic not required (21.6%), incorrect dose (12.9%), incorrect drug (11.5%), and incorrect duration of therapy (9.5%). This study demonstrates poor adherence to guidelines. Irrational use of antibiotics is associated with increased antibiotic resistance. There is an urgent need to improve antibiotic prescribing practice in primary care in the Cape Town Metro District.

Immunisation coverage in the rural Eastern Cape — are we getting the basics of primary care right? Results from a longitudinal prospective cohort study

PubMed Central

le Roux, K; Akin-Olugbade, O; Katzen, L S; Laurenzi, C; Mercer, N; Tomlinson, M; Rotheram-Borus, M J

2017-01-01

BACKGROUND Immunisations are one of the most cost-effective public health interventions available and South Africa (SA) has implemented a comprehensive immunisation schedule. However, there is disagreement about the level of immunisation coverage in the country and few studies document the immunisation coverage in rural areas. OBJECTIVE To examine the successful and timely delivery of immunisations to children during the first 2 years of life in a deeply rural part of the Eastern Cape Province ot SA. METHODS From January to April 2013, a cohort of sequential births (N=470) in the area surrounding Zithulele Hospital in the OR Tambo District of the Eastern Cape was recruited and followed up at home at 3, 6, 9,12 and 24 months post birth, up to May 2015. Immunisation coverage was determined using Road-to-Health cards. RESULTS The percentages of children with all immunisations up to date at the time of interview were: 48.6% at 3 months, 73.3% at 6 months, 83.9% at 9 months, 73.3% at 12 months and 73.2% at 24 months. Incomplete immunisations were attributed to stock-outs (56%), lack of awareness of the immunisation schedule or of missed immunisations by the mother (16%) and lack of clinic attendance by the mother (19%). Of the mothers who had visited the clinic for baby immunisations, 49.8% had to make multiple visits because of stock-outs. Measles coverage (of at least one dose) was 85.2% at 1 year and 96.3% by 2 years, but 20.6% of babies had not received a second measles dose (due at 18 months) by 2 years. Immunisations were often given late, particularly the 14-week immunisations. CONCLUSIONS Immunisation rates in the rural Eastern Cape are well below government targets and indicate inadequate provision of basic primary care. Stock-outs of basic childhood immunisations are common and are, according to mothers, the main reason for their childrens immunisations not being up to date. There is still much work to be done to ensure that the basics of disease prevention are being delivered at rural clinics in the Eastern Cape, despite attempts to re-engineer primary healthcare in SA. PMID:28112092

Earth observations Cape Town, South Africa taken during the STS-97 mission

NASA Image and Video Library

2000-12-10

STS097-711-069 (30 Nov. - 11 Dec. 2000) This view featuring Cape Town and the Western Cape Province in the Republic of South Africa was provided by one of the STS-97 astronauts using a 70mm handheld camera aboard the Earth-orbiting Space Shuttle Endeavour. The capital and largest city of Western Cape Province, Cape Town (1995 population in the urban and suburban area shows in excess of 1.9 million), is visible between False Bay (large, U-shaped bay) and a smaller bay along the Atlantic coast of the peninsula. Within the urban built-up area some of the infrastructure of Cape Town, including the city center and the harbor and waterfront facilities, can be identified near the small bay (middle left edge of the image). Table Mountain elevation of 3563 feet (1086 meters above sea level) separates the city center (north of the mountain) from the southern suburbs of Cape Town. The Cape of Good Hope, long famous as the gateway from the Atlantic Ocean to the Indian Ocean, is located at the southern tip of the claw-shaped peninsula. False Bay is a popular recreational region for the local residents of the greater Cape Town region, as well as a tourist attraction for people who live beyond the borders of South Africa. The lighter-colored terrain, mainly north of Cape Town, shows a landscape of large, cultivated field patterns. These coastal plains are separated from the interior by a chain of folded mountain ranges that include the Cedarberg (dark, linear, north/south aligned feature in the upper right corner) and the more complex, folded Herrivierberge Mountains (dark structure, right middle) that are located northeast of Cape Town.

Caffeic acid phenethyl ester down-regulates claudin-2 expression at the transcriptional and post-translational levels and enhances chemosensitivity to doxorubicin in lung adenocarcinoma A549 cells.

PubMed

Sonoki, Hiroyuki; Tanimae, Asami; Furuta, Takumi; Endo, Satoshi; Matsunaga, Toshiyuki; Ichihara, Kenji; Ikari, Akira

2018-06-01

Claudin-2 is highly expressed in human lung adenocarcinoma cells and involved in the promotion of proliferation. Here, we searched for a compound, which can decrease claudin-2 expression using lung adenocarcinoma A549 cells. In the screening using compounds included in royal jelly and propolis, the protein level of claudin-2 was dose-dependently decreased by caffeic acid phenethyl ester (CAPE), whereas the mRNA level and promoter activity were only decreased by 50 μM CAPE. These results suggest that CAPE down-regulates claudin-2 expression mediated by two different mechanisms. CAPE (50 μM) decreased the level of p-NF-κB, whereas it increased that of IκB. The CAPE-induced decrease in promoter activity of claudin-2 was blocked by the mutation in an NF-κB-binding site. The inhibition of NF-κB may be involved in the decrease in mRNA level of claudin-2. The CAPE (10 μM)-induced decrease in claudin-2 expression was inhibited by chloroquine, a lysosomal inhibitor. CAPE increased the expression and activity of protein phosphatase (PP) 1 and 2A. The CAPE-induced decrease in claudin-2 expression was blocked by cantharidin, a potent PPs inhibitor. The cell proliferation was suppressed by CAPE, which was partially rescued by ectopic expression of claudin-2. In addition, the toxicity and accumulation of doxorubicin in 3D spheroid cells were enhanced by CAPE, which was inhibited by ectopic expression of claudin-2. Taken together, CAPE down-regulates claudin-2 expression at the transcriptional and post-translational levels, and enhances sensitivity of cells to doxorubicin in 3D culture conditions. CAPE may be a useful adjunctive compound in the treatment of lung adenocarcinoma. Copyright © 2018 Elsevier Inc. All rights reserved.

ICT applications as e-health solutions in rural healthcare in the Eastern Cape Province of South Africa.

PubMed

Ruxwana, Nkqubela L; Herselman, Marlien E; Conradie, D Pieter

Information and Communication Technology (ICT) solutions (e.g. e-health, telemedicine, e-education) are often viewed as vehicles to bridge the digital divide between rural and urban healthcare centres and to resolve shortcomings in the rural health sector. This study focused on factors perceived to influence the uptake and use of ICTs as e-health solutions in selected rural Eastern Cape healthcare centres, and on structural variables relating to these facilities and processes. Attention was also given to two psychological variables that may underlie an individual&s acceptance and use of ICTs: usefulness and ease of use. Recommendations are made with regard to how ICTs can be used more effectively to improve health systems at fi ve rural healthcare centres where questionnaire and interview data were collected: St. Lucy&s Hospital, Nessie Knight Hospital, the Tsilitwa Clinic, the Madzikane Ka-Zulu Memorial Hospital and the Nelson Mandela General Hospital.

Analysis of the Cape Cod tracer data

USGS Publications Warehouse

Ezzedine, Souheil; Rubin, Yoram

1997-01-01

An analysis of the Cape Cod test was performed using several first- and higher-order theoretical models. We compare conditional and unconditional solutions of the transport equation and employ them for analysis of the experimental data. We consider spatial moments, mass breakthrough curves, and the distribution of the solute mass in space. The concentration measurements were also analyzed using theoretical models for the expected value and variance of concentration. The theoretical models we employed are based on the spatial correlation structure of the conductivity field, without any fitting of parameters to the tracer data, and hence we can test the predictive power of the theories tested. The effects of recharge on macrodispersion are investigated, and it is shown that recharge provides a reasonable explanation for the enhanced lateral spread of the Cape Cod plume. The compendium of the experimental results presented here is useful for testing of theoretical and numerical models.

Environmental monitoring of pesticide residues from farms at a neighbouring primary and pre-school in the Western Cape in South Africa.

PubMed

Dalvie, M A; Sosan, M B; Africa, A; Cairncross, E; London, L

2014-01-01

Concerns about pesticide drift from neighbouring vineyards affecting children attending school on a farm adjacent to an urban suburb of Cape Town, Western Cape in South Africa were investigated. The study involved a before-after design, measuring levels of environmental exposure before and during pesticide application activities on the neighbouring farms. Samples were collected in air, dust and grass cuttings at the preschool and primary school located on the farms during September-December in 2010 and tested for pesticides using multi-pesticide methods. Eleven different pesticides were detected in the various samples. Six of these chemicals (endosulfan, dimethomorph, penconazole, cyprodinil, boscalid and bromopropylate) were on the spraying schedules of the two farms neighbouring the schools and the timing and location of detection were generally consistent with farm application. Three pesticides detected (chlorpyrifos, cypermethrin, permethrin) are agents commonly used in household applications and one (pyriproxifen) is used in pet treatment agents. Kresoxim-methyl, the other pesticide detected, is likely to come from drift from other farms in the area. The concentration of pesticides was all lower than 0.1 μg/m(3) in air and 0.1 μg/kg in dust and grass apart from permethrin and cypermethrin. The findings confirm the presence of drift onto the school premises and concentrations found in this study were generally low in comparison to that detected in other studies. Regular monitoring to track the effectiveness of containment and mitigation measures that reduce drift is recommended. © 2013.

75 FR 62320 - Safety Zone; Fireworks for USS GRAVELY Commissioning Ceremony, Cape Fear River, Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-08

...-AA00 Safety Zone; Fireworks for USS GRAVELY Commissioning Ceremony, Cape Fear River, Wilmington, NC... zone on the navigable waters of Cape Fear River in Wilmington, NC in support of the Fireworks for the... western shore of the Cape Fear River at Battleship Park. The fireworks debris fallout area will extend...

33 CFR 165.515 - Safety Zone: Cape Fear River, Wilmington, North Carolina.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zone: Cape Fear River... § 165.515 Safety Zone: Cape Fear River, Wilmington, North Carolina. (a) Location. The following area is a safety zone: (1) The waters of the Cape Fear River bounded by a line connecting the following...

78 FR 37963 - Safety Zone; Fifth Coast Guard District Fireworks Display Cape Fear River; Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-25

...-AA00 Safety Zone; Fifth Coast Guard District Fireworks Display Cape Fear River; Wilmington, NC AGENCY... District. This regulation applies to only one recurring fireworks event, held adjacent to the Cape Fear... of the Cape Fear River, Wilmington, North Carolina, during the event. DATES: This rule will be...

Validation of the Spanish Version of the CAPES: A Brief Instrument for Assessing Child Psychological Difficulties and Parental Self-Efficacy

ERIC Educational Resources Information Center

Mejia, Anilena; Filus, Ania; Calam, Rachel; Morawska, Alina; Sanders, Matthew R.

2016-01-01

In the present study, we explored the factor structure as well as validity and reliability of the Spanish version of the Child Adjustment and Parent Efficacy Scale (CAPES) suitable for assessing child behavioural and emotional difficulties (Intensity Scale) and parental self-efficacy (Self-Efficacy Scale) among Spanish-speaking parents from the…

76 FR 76154 - Natural Currents Energy Services, LLC; Notice of Preliminary Permit Application Accepted for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-06

... annual minimum generation of 3,504,000 kilowatt-hours with the installation of 10 units. Applicant... Services, LLC filed an application, pursuant to section 4(f) of the Federal Power Act, proposing to study the feasibility of the Cape May Tidal Energy Project, which would be located on the Cape May Canal in...

An Investigation into How Grade 5 Teachers Teach Natural Science Concepts in Three Western Cape Primary Schools

ERIC Educational Resources Information Center

Set, Beata; Hadman, Joanne; Ashipala, Daniel Opotamutale

2017-01-01

Purpose: The rationale behind this study was to investigate how three Grade 5 Natural Sciences teachers in three Western Cape primary schools teach science concepts so as to enable the researcher to gain a deeper understanding and more insightful perception of the ways in which the pedagogical practices of South African primary school teachers…

Disempowerment and Psychological Distress in the Lives of Young People in Eastern Cape, South Africa

ERIC Educational Resources Information Center

Nduna, Mzikazi; Jewkes, Rachel

2012-01-01

A qualitative study was conducted in Butterworth, in the rural Eastern Cape Province of South Africa, to explore sources of distress for young people. Semi-structured, individual in-depth interviews were conducted with 16 men and 24 women aged 16-22 years. The findings revealed interconnections between structural factors such as death, poverty,…

Coordinated field study for CaPE: Analysis of energy and water budgets

NASA Technical Reports Server (NTRS)

Goodman, Steven J.; Duchon, Claude; Kanemasu, Edward T.; Smith, Eric A.; Crosson, William; Laymon, Chip; Luvall, Jeff

1993-01-01

The objectives of this hydrologic cycle study are to understand and model (1) surface energy and land-atmosphere water transfer processes, and (2) interactions between convective storms and surface energy fluxes. A surface energy budget measurement campaign was carried out by an interdisciplinary science team during the period July 8 - August 19, 1991 as part of the Convection and Precipitation/Electrification Experiment (CaPE) in the vicinity of Cape Canaveral, FL. Among the research themes associated with CaPE is the remote estimation of rainfall. Thus, in addition to surface radiation and energy budget measurements, surface mesonet, special radiosonde, precipitation, high-resolution satellite (SPOT) data, geosynchronous (GOES) and polar orbiting (DMSP SSM/I, OLS; NOAA AVHRR) satellite data, and high altitude airplane data (AMPR, MAMS, HIS) were collected. Initial quality control of the seven surface flux station data sets has begun. Ancillary data sets are being collected and assembled for analysis. Browsing of GOES and radar data has begun to classify days as disturbed/undisturbed to identify the larger scale forcing of the pre-convective environment, convection storms and precipitation. The science analysis plan has been finalized and tasks assigned to various investigators.

Key aspects of cost effective collector and solar field design

NASA Astrophysics Data System (ADS)

von Reeken, Finn; Nicodemo, Dario; Keck, Thomas; Weinrebe, Gerhard; Balz, Markus

2016-05-01

A study has been performed where different key parameters influencing solar field cost are varied. By using levelised cost of energy as figure of merit it is shown that parameters like GoToStow wind speed, heliostat stiffness or tower height should be adapted to respective site conditions from an economical point of view. The benchmark site Redstone (Northern Cape Province, South Africa) has been compared to an alternate site close to Phoenix (AZ, USA) regarding site conditions and their effect on cost-effective collector and solar field design.

Strategic analysis for the MER Cape Verde approach

USGS Publications Warehouse

Gaines, D.; Belluta, P.; Herman, J.; Hwang, P.; Mukai, R.; Porter, D.; Jones, B.; Wood, E.; Grotzinger, J.; Edgar, L.; Hayes, A.; Hare, T.; Squyres, S.

2009-01-01

The Mars Exploration Rover Opportunity has recently completed a two year campaign studying Victoria Crater. The campaign culminated in a close approach of Cape Verde in order to acquire high resolution imagery of the exposed stratigraphy in the cliff face. The close approach to Cape Verde provided significant challenges for every subsystem of the rover as the rover needed to traverse difficult, uncharacterised terrain and approach a cliff face with the potential of blocking out solar energy and communications with Earth. In this paper we describe the strategic analyses performed by the science and engineering teams so that we could successfully achieve the science objectives while keeping the rover safe. ??2009 IEEE.

KSC-2013-4536

NASA Image and Video Library

2013-11-28

CAPE CANAVERAL, Fla. – At Cape Canaveral Air Force Station's Atlas V Spaceflight Operations Center NASA managers monitor progress of the countdown for the launch the agency's Mars Atmosphere and Volatile Evolution, or MAVEN, spacecraft. From the left are Amanda Mitskevich, program manager of NASA's Launch Services Program, or LSP, and Chuck Dovale, deputy program manager of LSP. MAVEN was launched on Nov. 18, 2013 from Cape Canaveral's Space Launch Complex 41 atop a United Launch Alliance Atlas V rocket. Positioned in an orbit above the Red Planet, MAVEN will study the upper atmosphere of Mars in unprecedented detail. For more information, visit: http://www.nasa.gov/mission_pages/maven/main/index.html Photo credit: NASA/Kim Shiflett

Noachian Impact Ejecta on Murray Ridge and Pre-impact Rocks on Wdowiak Ridge, Endeavour Crater, Mars: Opportunity Observations

NASA Technical Reports Server (NTRS)

Mittlefehldt, D. W.; Gellert, R.; Ming, D. W.; Morris, R. V.; Schroeder, C.; Yen, A. S.; Farrand, W. H.; Arvidson, R. E.; Franklin, B. J.; Grant, J. A.;

The use of garden boreholes in Cape Town, South Africa: lessons learnt from Perth, Western Australia

NASA Astrophysics Data System (ADS)

Saayman, I. C.; Adams, S.

The similarities in climate and geology offer water resource managers in Cape Town and Perth an opportunity to learn from each other's experiences. While Cape Town relies mostly on surface water for supply, Perth uses 50% groundwater for its domestic and industrial use. It is proposed that certain aspects of Perth's water supply infrastructure could successfully be transposed for the exploitation of Cape Towns' groundwater resources. In Perth private boreholes is used to tap a shallow phreatic aquifer for garden irrigation. The Government of Western Australia encourages this practice. Cape Town has an opportunity to use water from the Cape Flats Aquifer in a similar manner. In this paper the use of the Cape Flats Aquifer for private garden irrigation is evaluated. By encouraging private landowners to develop private wells, large savings could be made in the amount of treated bulk water supply required by Cape Town. The Cape Flats Aquifer has the potential to meet a large part of the city's garden irrigation requirements. Though the impact of pollution on water quality remains uncertain and a concern, the general quality of water in the aquifer is adequate for irrigation requirements. If the use of private garden boreholes is to be successful, education of the public will be vital. It is envisaged that the City of Cape Town and the Department of Water Affairs and Forestry in partnership with private, education and research institutions take the lead in such education and the development of appropriate legislation and guidelines.

Intraplate seismicity across the Cape Verde swell

NASA Astrophysics Data System (ADS)

Vales, Dina; Matias, Luís.; Haberland, Christian; Silveira, Graça.; Weber, Michael; Carrilho, Fernando; Dias, Nuno

2010-05-01

The Cape Verde Archipelago ((15-17°N, 23-26°W) is located within the African plate, about 500km west of Senegal, in the African coast. The islands are located astride the Cape Verde mid-plate topographic swell, one of the largest features of its type in the world's ocean basins. The origin of this Cape Verde swell is still in debate. Previous determinations of the elastic thickness (Te) reveal a normal Te and a modest heat flow anomaly which suggest that the swell cannot be fully explained by uplift due to thermal reheating of the lithosphere by an underlying ‘‘hot spot'' and that other, deep-seated, mantle processes must be involved. The CV-PLUME (An investigation on the geometry and deep signature of the Cape Verde mantle plume) project intends to shape the geometry and deep origin of the Cape Verde mantle plume, via a combined study of seismic, magnetic, gravimetric and geochemical observations. Through this study we intend to characterize the structure beneath the archipelago from the surface down to the deep mantle. The core of this 3-year project was a temporary deployment of 39 Very Broad Band seismometers, across all the inhabited islands, to recorder local and teleseismic earthquakes. These instruments were operational from November 2007 to September 2008. In this work we report on the preliminary results obtained from the CV-PLUME network on the characterization of the local and regional seismicity. To detect the small magnitude seismic events the continuous data stream was screened using spectrograms. This proved to be a very robust technique in the face of the high short-period noise recorded by many of the stations, particularly during day time. The 10 month observation time showed that the background seismic activity in the Archipelago and surrounding area is low, with only a very few events recorded by the complete network. However, two clusters of earthquakes were detected close to the Brava Island, one to the NW and a second one, more active, to the SW. This activity was concentrated mainly during January 2008. The Brava and nearby Fogo Islands are known for their recent volcanic activity (last eruption in Fogo was in April 1995) and earthquake swarms. Therefore, we infer that the recorded seismic activity may be also triggered by magma flow. This study was funded by project "CV-PLUME: An investigation on the geometry and deep signature of the Cape Verde mantle plume", reference - PTDC/CTE-GIN/64330/2006; and Germany - "COBO: Cape Verdes Origin from Broadband Observations, GFZ, Geophysical Deep Sounding Section. The operation was possible thanks to the cooperation between the GeoForschungsZentrum Potsdam (Germany's National Research Centre for Geosciences) with the Instituto Dom Luiz.

Lessons Learnt from Employing van Hiele Theory Based Instruction in Senior Secondary School Geometry Classrooms

ERIC Educational Resources Information Center

Alex, Jogymol Kalariparambil; Mammen, Kuttickattu John

2016-01-01

This paper reports on a part of a study which was conducted to determine the effect of van Hiele theory based instruction in the teaching of geometry to Grade 10 learners. The sample consisted of 359 participants from five conveniently selected schools from Mthatha District in the Eastern Cape Province in South Africa. There were 195 learners in…

Cape Verdeans in the United States (Continuing a Story of Struggle, Creativity and Persistence).

ERIC Educational Resources Information Center

Houston, Laura Pires

This article focuses on the history of the Cape Verde Islands, the nature of Cape Verdean immigration to the United States, and the ethnic experience of Cape Verdeans in the U.S. The colonization of the Atlantic archipelago by the Portuguese as part of their expanding slave trade is described and the Islands' economic, ecologic, racial and…

33 CFR 334.1330 - Bering Strait, Alaska; naval restricted area off Cape Prince of Wales.

Code of Federal Regulations, 2010 CFR

2010-07-01

... restricted area off Cape Prince of Wales. 334.1330 Section 334.1330 Navigation and Navigable Waters CORPS OF....1330 Bering Strait, Alaska; naval restricted area off Cape Prince of Wales. (a) The area. An area 2,000 feet wide extending from a point on Cape Prince of Wales marked by a triangular cable marker located...

77 FR 44468 - Safety Zone; Fireworks for NC NENA/APCO Conference, Cape Fear River; Wilmington, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

... 1625-AA00 Safety Zone; Fireworks for NC NENA/APCO Conference, Cape Fear River; Wilmington, NC AGENCY... on the navigable waters of Cape Fear River; Wilmington, NC in support of the Fireworks display for... shore of the Cape Fear River at Battleship Park. The fireworks debris fallout area will extend over the...

Geochemical constraints on depth of origin of oceanic carbonatites: The Cape Verde case

NASA Astrophysics Data System (ADS)

Doucelance, Régis; Hammouda, Tahar; Moreira, Manuel; Martins, João C.

2010-12-01

We present new Sr-Nd isotope compositions together with major- and trace element concentrations measured for whole rocks and mineral separate phases (apatite, biotite and calcite) from fifteen Cape Verde oceanic carbonatites (Atlantic Ocean). Trace element patterns of calcio- and magnesio-carbonatites present a strong depletion in K, Hf, Zr and Ti and an overall enrichment in Sr and REE relative to Cape Verde basalts, arguing for distinct source components between carbonatites and basalts. Sr and Nd isotopic ratios show small, but significant variations defining a binary mixing between a depleted end-member with unradiogenic Sr and radiogenic Nd values and a ''enriched'' end-member compatible with old marine carbonates. We interpret the depleted end-member as the Cape Verde oceanic lithosphere by comparison with previous studies on Cape Verde basalts. We thus propose that oceanic carbonatites are resulting from the interaction of a deep rooted mantle plume carrying a lower 4He/ 3He signature from the lower mantle and a carbonated metasomatized lithosphere, which by low degree melting produced carbonatite magmas. Sr-Nd compositions and trace element patterns of carbonatites argue in favor of a metasomatic agent originating from partial melting of recycled, carbonated oceanic crust. We have successfully reproduced the main geochemical features of this model using a Monte-Carlo-type simulation.

Sediment transport on Cape Sable, Everglades National Park, Florida

USGS Publications Warehouse

Zucker, Mark; Boudreau, Carrie

2010-01-01

The Cape Sable peninsula is located on the southwestern tip of the Florida peninsula within Everglades National Park (ENP). Lake Ingraham, the largest lake within Cape Sable, is now connected to the Gulf of Mexico and western Florida Bay by canals built in the early 1920's. Some of these canals breached a natural marl ridge located to the north of Lake Ingraham. These connections altered the landscape of this area allowing for the transport of sediments to and from Lake Ingraham. Saline intrusion into the formerly fresh interior marsh has impacted the local ecology. Earthen dams installed in the 1950's and 1960's in canals that breached the marl ridge have repeatedly failed. Sheet pile dams installed in the early 1990's subsequently failed resulting in the continued alteration of Lake Ingraham and the interior marsh. The Cape Sable Canals Dam Restoration Project, funded by ENP, proposes to restore the two failed dams in Lake Ingraham. The objective of this study was to collect discharge and water quality data over a series of tidal cycles and flow conditions to establish discharge and sediment surrogate relations prior to initiating the Cape Sable Canals Dam Restoration Project. A dry season synoptic sampling event was performed on April 27-30, 2009.

Cape Canaveral Air Force Station, Launch Complex 39, Solid Rocket ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Cape Canaveral Air Force Station, Launch Complex 39, Solid Rocket Booster Disassembly & Refurbishment Complex, Thrust Vector Control Deservicing Facility, Hangar Road, Cape Canaveral, Brevard County, FL

Earth observations taken from shuttle orbiter Atlantis during STS-84 mission

NASA Image and Video Library

1997-07-09

STS084-703-003 (15-24 May 1997) --- Cape Cod extends 105 kilometers (65 miles) into the Atlantic Ocean. To the south of Cape Cod are the islands of Martha's Vineyard (west) and Nantucket (east). The city of Boston can be seen surrounding the bay above the "hook" on Cape Cod. To the south are the cities of New Bedford on Buzzards Bay, and Providence, Rhode Island. The Cape Cod Canal is an artificial waterway that connects Buzzards Bay and Cape Cod Bay. The waterway is 28 kilometers (17.5 miles) and does not contains locks. The canal was built to shorten the distance over water between New York City and Boston. In 1620 the Pilgrims landed at Provincetown, on the upper tip of Cape Cod, before they proceeded to Plymouth.

Assessing the effectiveness of botulinum toxin injections for adductor spasmodic dysphonia: clinician and patient perception.

PubMed

Braden, Maia N; Johns, Michael M; Klein, Adam M; Delgaudio, John M; Gilman, Marina; Hapner, Edie R

2010-03-01

To determine the effectiveness of Botox treatment for adductor spasmodic dysphonia (ADSD), the clinician and patient judge changes in voice symptoms and the effect on quality of life. Currently, there is no standard protocol for determining the effectiveness of Botox injections in treating ADSD. Therefore, clinicians use a variety of perceptual scales and patient-based self-assessments to determine patients' impressions of severity and changes after treatments. The purpose of this study was to assess clinician-patient agreement of the effects of Botox on voice quality and quality of life in ADSD. Retrospective chart review of 199 randomly selected patients since 2004. Results indicated a weak correlation between the patient's assessment of voice impairment (EIS) and patient's quality of life impairment (Voice-Related Quality of Life [V-RQOL]) in the mild-moderate dysphonia severity group and the moderate-to-severe dysphonia group. There was a weak correlation between the patient's assessment of voice impairment EIS and the clinician's perceptual judgment of voice impairment (Consensus Auditory Perceptual Evaluation of Voice [CAPE-V]) only in the moderate to severe dysphonia group. There was a weak correlation between the patient's quality of life impairment (V-RQOL) and the clinician's perceptual judgment of voice impairment (CAPE-V) only in the severe to profound dysphonia group. The poor relationship among commonly used outcome measures leads us to question how best to assess the effectiveness of Botox in ADSD. Clinicians are required to document treatment outcomes, making it important to use scales that are valid, reliable, and sensitive to change. Future research directions include examining relationships between measures both before and after Botox injections, examining the specific factors that determine quality of life changes, and further research on specific parameters of the CAPE-V as well as comparing perceptual and quality of life scales with acoustic and aerodynamic measures in this population would be beneficial in the move toward more effective ways of measuring change. Copyright (c) 2010 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

Extinction Risk and Diversification Are Linked in a Plant Biodiversity Hotspot

PubMed Central

Davies, T. Jonathan; Smith, Gideon F.; Bellstedt, Dirk U.; Boatwright, James S.; Bytebier, Benny; Cowling, Richard M.; Forest, Félix; Harmon, Luke J.; Muasya, A. Muthama; Schrire, Brian D.; Steenkamp, Yolande; van der Bank, Michelle; Savolainen, Vincent

2011-01-01

It is widely recognized that we are entering an extinction event on a scale approaching the mass extinctions seen in the fossil record. Present-day rates of extinction are estimated to be several orders of magnitude greater than background rates and are projected to increase further if current trends continue. In vertebrates, species traits, such as body size, fecundity, and geographic range, are important predictors of vulnerability. Although plants are the basis for life on Earth, our knowledge of plant extinctions and vulnerabilities is lagging. Here, we disentangle the underlying drivers of extinction risk in plants, focusing on the Cape of South Africa, a global biodiversity hotspot. By comparing Red List data for the British and South African floras, we demonstrate that the taxonomic distribution of extinction risk differs significantly between regions, inconsistent with a simple, trait-based model of extinction. Using a comprehensive phylogenetic tree for the Cape, we reveal a phylogenetic signal in the distribution of plant extinction risks but show that the most threatened species cluster within short branches at the tips of the phylogeny—opposite to trends in mammals. From analyzing the distribution of threatened species across 11 exemplar clades, we suggest that mode of speciation best explains the unusual phylogenetic structure of extinction risks in plants of the Cape. Our results demonstrate that explanations for elevated extinction risk in plants of the Cape flora differ dramatically from those recognized for vertebrates. In the Cape, extinction risk is higher for young and fast-evolving plant lineages and cannot be explained by correlations with simple biological traits. Critically, we find that the most vulnerable plant species are nonetheless marching towards extinction at a more rapid pace but, surprisingly, independently from anthropogenic effects. Our results have important implications for conservation priorities and cast doubts on the utility of current Red List criteria for plants in regions such as the Cape, where speciation has been rapid, if our aim is to maximize the preservation of the tree-of-life. PMID:21629678

Ground-water level data for North Carolina, 1987

USGS Publications Warehouse

Coble, Ronald W.; Strickland, A.G.; Bailey, M. Carl

1989-01-01

Continuous and periodic measurements in 54 key wells and water-level measurements emplaced in Coastal Plain aquifers across North Carolina in 193 supplemental wells are presented in this report. Hydrographs of selected wells show changes in ground-water storage in the State. The water table in the shallow aquifers was higher throughout most of the State in 1987 than in 1986, indicating that rain had recharged these aquifers sufficiently to replenish the deficit in ground water storage that accumulated in the western and central parts of the State during 1986. Water levels in the heavily pumped Coastal Plain aquifers show a general downward trend for the year, indicating ground water is being withdrawn from aquifer storage. Record low water levels were measured in 4 of 13 wells in the Castle Hayne aquifer; the greatest decline measured during 1987 was 0.3 ft. Water levels in wells in the Peedee, Black Creek, upper Cape Fear, and lower Cape Fear aquifers generally show downward trends. Record low water levels were measured in 4 of 8 wells in the Peedee aquifer; the maximum decline measured during 1987 was 1.5 ft. All wells in the Black Creek, upper Cape Fear, and lower Cape Fear aquifers had record low water levels for 1987, with maximum measured declines in 1987 of 8.6, 3.1, and 3.1 ft., respectively. Record high water levels were measured in two wells, one each in the Castle Hayne and Peedee aquifers. Potentiometric surface maps show the effects of major centers of pumping for the Castle Hayne, Black Creek, and lower Cape Fear aquifers of the Coastal Plain.

Characterization of convection-related parameters by Raman lidar: Analysis of selected case studies from the Convective and Orographically-induced Precipitation Study

NASA Astrophysics Data System (ADS)

Di Girolamo, P.; Summa, D.; Stelitano, D.

2012-04-01

This paper illustrates an approach to determine the convective available potential energy (CAPE) and the convective inhibition (CIN) based on the use of data from a Raman lidar system. The use of Raman lidar data allows to provide high temporal resolution (5 min) measurements of CAPE and CIN and follow their evolution over extended time period covering the full cycle of convective activity. Lidar-based measurements of CAPE and CIN are obtained from Raman lidar measurements of the temperature profile and the surface measurements of temperature, pressure and dew point temperature provided from a surface weather station. The approach is tested and applied to the data collected by the Raman lidar system BASIL, which was operational in Achern (Black Forest, Lat: 48.64 ° N, Long: 8.06 ° E, Elev.: 140 m) in the period 01 June - 31 August 2007 in the frame of the Convective and Orographically-induced Precipitation Study (COPS), held in Southern Germany and Eastern France. Reported measurements are found to be in good agreement with simultaneous measurements obtained from the radiosondes launched in Achern and with estimates from different mesoscale models. An estimate of the different random error sources affecting the measurements of CAPE and CIN has also been performed, together with a detail sensitivity study to quantify the different systematic error sources. Preliminary results from this study will be illustrated and discussed at the Conference.

Identification of hydraulic conductivity structure in sand and gravel aquifers: Cape Cod data set

USGS Publications Warehouse

Eggleston, J.R.; Rojstaczer, S.A.; Peirce, J.J.

1996-01-01

This study evaluates commonly used geostatistical methods to assess reproduction of hydraulic conductivity (K) structure and sensitivity under limiting amounts of data. Extensive conductivity measurements from the Cape Cod sand and gravel aquifer are used to evaluate two geostatistical estimation methods, conditional mean as an estimate and ordinary kriging, and two stochastic simulation methods, simulated annealing and sequential Gaussian simulation. Our results indicate that for relatively homogeneous sand and gravel aquifers such as the Cape Cod aquifer, neither estimation methods nor stochastic simulation methods give highly accurate point predictions of hydraulic conductivity despite the high density of collected data. Although the stochastic simulation methods yielded higher errors than the estimation methods, the stochastic simulation methods yielded better reproduction of the measured In (K) distribution and better reproduction of local contrasts in In (K). The inability of kriging to reproduce high In (K) values, as reaffirmed by this study, provides a strong instigation for choosing stochastic simulation methods to generate conductivity fields when performing fine-scale contaminant transport modeling. Results also indicate that estimation error is relatively insensitive to the number of hydraulic conductivity measurements so long as more than a threshold number of data are used to condition the realizations. This threshold occurs for the Cape Cod site when there are approximately three conductivity measurements per integral volume. The lack of improvement with additional data suggests that although fine-scale hydraulic conductivity structure is evident in the variogram, it is not accurately reproduced by geostatistical estimation methods. If the Cape Cod aquifer spatial conductivity characteristics are indicative of other sand and gravel deposits, then the results on predictive error versus data collection obtained here have significant practical consequences for site characterization. Heavily sampled sand and gravel aquifers, such as Cape Cod and Borden, may have large amounts of redundant data, while in more common real world settings, our results suggest that denser data collection will likely improve understanding of permeability structure.

33 CFR 334.450 - Cape Fear River and tributaries at Sunny Point Army Terminal, Brunswick County, N.C.; restricted...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Cape Fear River and tributaries... AND RESTRICTED AREA REGULATIONS § 334.450 Cape Fear River and tributaries at Sunny Point Army Terminal, Brunswick County, N.C.; restricted area. (a) The area. That portion of Cape Fear River due west of the main...

33 CFR 80.530 - Cape Fear, NC to Little River Inlet, NC.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cape Fear, NC to Little River... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Fifth District § 80.530 Cape Fear, NC to... latitude 33°52.4′ N. longitude 78°00.1′ W. across the Cape Fear River Entrance to Oak Island Light. (b...

Cape queer? A case study of Provincetown, Massachusetts.

PubMed

Krahulik, Karen Christel

2006-01-01

Cape Queer is a case study that details how sexuality intersects with race, gender, and class in the development of the gay and lesbian resort community, Provincetown, Massachusetts. It asks scholars to pay closer attention to the ways in which methodologies and practices utilizing LGBT studies and queer theory can combine rather than separate to interrogate LGBT and queer histories, politics and communities. In the process, it assesses how the global mechanics of capitalism led to the local queering and eventually un-queering of a gentrified, white, gay and lesbian enclave.

Cultural Resources Intensive Survey and Testing of Mississippi River Levee Berms Crittenden and Desha Counties, Arkansas and Mississippi, Scott, Cape Girardeau and Pemiscot Counties, Missouri. Item R-48.87 A.C. Nash; Missouri, Relief Well Ditches Cape Girardeau and Scott Counties, Missouri

DTIC Science & Technology

1983-07-01

denizens and occurred in the study area. Maps presented by Simpson (1945) indicate that the genus Tapirus ( tapirs ) occurred in the study area. Mosimann and...Felines in North America. The American Museum of Natural History, No. 1136, pp. 20-27. 1945 Notes on Pleistocene and Recent Tapirs . Bulletin of the

Panorama from 'Cape Verde'

NASA Technical Reports Server (NTRS)

2007-01-01

NASA's Mars Exploration Rover Opportunity captured this vista of 'Victoria Crater' from the viewpoint of 'Cape Verde,' one of the promontories that are part of the scalloped rim of the crater. Opportunity drove onto Cape Verde shortly after arriving at the rim of Victoria in September 2006. The view combines hundreds of exposures taken by the rover's panoramic camera (Pancam). The camera began taking the component images during Opportunity's 970th Martian day, or sol, on Mars (Oct. 16, 2006). Work on the panorama continued through the solar conjunction period, when Mars was nearly behind the sun from Earth's perspective and communications were minimized. Acquisition of images for this panorama was completed on Opportunity's 991st sol (Nov. 7, 2006).

The top of Cape Verde is in the immediate foreground at the center of the image. To the left and right are two of the more gradually sloped bays that alternate with the cliff-faced capes or promontories around the rim of the crater. 'Duck Bay,' where Opportunity first reached the rim, is to the right. Beyond Duck Bay counterclockwise around the rim, the next promontory is 'Cabo Frio,' about 150 meters (500 feet) from the rover. On the left side of the panorama is 'Cape St. Mary,' the next promontory clockwise from Cape Verde and about 40 meters (130 feet) from the rover. The vantage point atop Cape Verde offered a good view of the rock layers in the cliff face of Cape St. Mary, which is about 15 meters or 50 feet tall. By about two weeks after the Pancam finished collecting the images for this panorama, Opportunity had driven to Cape St. Mary and was photographing Cape Verde's rock layers.

The far side of the crater lies about 800 meters (half a mile) away, toward the southeast.

This approximately true-color view combines images taken through three of the Pancam's filters, admitting light with wavelengths centered at 750 nanometers (near infrared), 530 nanometers (green) and 430 nanometers (violet).

The Role of Postgraduate Students in Co-Authoring Open Educational Resources to Promote Social Inclusion: A Case Study at the University of Cape Town

ERIC Educational Resources Information Center

Hodgkinson-Williams, Cheryl; Paskevicius, Michael

2012-01-01

Like many universities worldwide, the University of Cape Town (UCT) in South Africa has joined the open educational resources (OER) movement, making a selection of teaching and learning materials available through its OER directory, UCT OpenContent. However, persuading and then supporting busy academics to share their teaching materials as OER…

Reliability of the Norwegian Version of the Children's Assessment of Participation and Enjoyment (CAPE) and Preferences for Activities of Children (PAC)

ERIC Educational Resources Information Center

Nordtorp, Heidi L.; Nyquist, Astrid; Jahnsen, Reidun; Moser, Thomas; Strand, Liv Inger

2013-01-01

This study examined test-retest reliability of the Norwegian version of Children's Assessment of Participation and Enjoyment (CAPE), and Preferences for Activities of Children (PAC) in children with and without disabilities. Totally 141 children, 107 typically developing, mean age 11.1, and 34 with disabilities, mean age 14.2 years participated. A…

From Digital Divide to Digital Equity: Learners' ICT Competence in Four Primary Schools in Cape Town, South Africa

ERIC Educational Resources Information Center

Gudmundsdottir, G. B.

2010-01-01

This study explores factors influencing the digital divide in four schools in Cape Town, South Africa. Three of the schools are for disadvantaged learners whereas the fourth was previously for whites only. All the schools use ICT in their curriculum delivery and thereby support the emphasis of provincial educational authorities on ICT access for…

Hydrogeologic framework of the North Carolina Coastal Plain aquifer system

USGS Publications Warehouse

Winner, M.D.; Coble, R.W.

1989-01-01

The hydrogeologic framework of the North Carolina Coastal Plain aquifer system consists of ten aquifers separated by nine confining units. From top to bottom the aquifers are: the surficial aquifer, Yorktown aquifer, Pungo River aquifer, Castle Hayne aquifer, Beaufort aquifer, Peedee aquifer, Black Creek aquifer, upper Cape Fear aquifer, lower Cape Fear aquifer, and the Lower Cretaceous aquifer. The uppermost aquifer (the surficial aquifer in most places) is a water-table aquifer and the bottom of the system is underlain by crystalline bedrock. The sedimentary deposits forming the aquifers are of Holocene to Cretaceous age and are composed mostly of sand with lesser amounts of gravel and limestone. Confining units between aquifers are composed primarily of clay and silt. The thickness of the aquifers ranges from zero along the Fall Line to more than 10,000 feet at Cape Hatteras. Prominent structural features are the increasing easterly homoclinal dip of the sediments and the Cape Fear arch, the axis of which trends in a southeast direction. The stratigraphic continuity is determined from correlations of 161 geophysical logs along with data from drillers' and geologists' logs. Aquifers were defined by means of these logs plus water-level and water-quality data and evidence of the continuity of pumping effects. Eighteen hydrogeologic sections depict the correlation of these aquifers throughout the Coastal Plain.

Changes in the convective population and thermodynamic environments in convection-permitting regional climate simulations over the United States

NASA Astrophysics Data System (ADS)

Rasmussen, K. L.; Prein, A. F.; Rasmussen, R. M.; Ikeda, K.; Liu, C.

2017-11-01

Novel high-resolution convection-permitting regional climate simulations over the US employing the pseudo-global warming approach are used to investigate changes in the convective population and thermodynamic environments in a future climate. Two continuous 13-year simulations were conducted using (1) ERA-Interim reanalysis and (2) ERA-Interim reanalysis plus a climate perturbation for the RCP8.5 scenario. The simulations adequately reproduce the observed precipitation diurnal cycle, indicating that they capture organized and propagating convection that most climate models cannot adequately represent. This study shows that weak to moderate convection will decrease and strong convection will increase in frequency in a future climate. Analysis of the thermodynamic environments supporting convection shows that both convective available potential energy (CAPE) and convective inhibition (CIN) increase downstream of the Rockies in a future climate. Previous studies suggest that CAPE will increase in a warming climate, however a corresponding increase in CIN acts as a balancing force to shift the convective population by suppressing weak to moderate convection and provides an environment where CAPE can build to extreme levels that may result in more frequent severe convection. An idealized investigation of fundamental changes in the thermodynamic environment was conducted by shifting a standard atmospheric profile by ± 5 °C. When temperature is increased, both CAPE and CIN increase in magnitude, while the opposite is true for decreased temperatures. Thus, even in the absence of synoptic and mesoscale variations, a warmer climate will provide more CAPE and CIN that will shift the convective population, likely impacting water and energy budgets on Earth.

Dental needs of intellectualy disabled children attending six special educational facilities in Cape Town.

PubMed

Roberts, T; Chetty, M; Kimmie-Dhansay, F; Fieggen, K; Stephen, L X G

2016-05-25

To assess the dental needs of a group of children with intellectual disability (ID) attending six special educational facilities in Cape Town, South Africa. Methods. This was a cross-sectional study based on a convenience sampling method. One hundred and fifty-seven children with ID attending six special educational facilities in Cape Town were included in the survey. Five schools were exclusively funded by the State and one school received additional private financial support. The oral examinations complied with guidelines drafted by Special Olympics Special Smiles programme and the Centers for Disease Control, USA. The most common dental disorders requiring management were gingival disease (69%) and untreated dental caries (68%). Almost 50% of the children had missing teeth. Twenty-nine percent needed orthodontic correction of malocclusion and 7% had structural abnormalities of their teeth that required either aesthetic or functional intervention. Fillings were evident in only 8% of the children. Females required more dental treatment than males. The dental needs of children with ID increased with age. There were no significant differences in the dental needs of children attending State-funded schools and those attending the single school that received additional financial assistance. The frequency of unmet dental needs of children with ID attending special educational facilities in Cape Town was high and the dental care available to them was minimal. The study highlights the need for improved dental services to ensure that optimal oral health is accessible to children with ID attending special educational facilities in Cape Town.

Hepatitis B virus genotypes A1, A2 and E in Cape Verde: Unequal distribution through the islands and association with human flows

PubMed Central

Soares, Caroline C.; Niel, Christian; Lago, Barbara V.

2018-01-01

Hepatitis B virus (HBV) diversity has not been previously studied in Cape Verde. The archipelago was discovered in 1460 by Portuguese explorers, who brought African slaves to colonise the islands. In this study, we investigated the HBV characteristics from 183 HBsAg-positive Cape Verdean individuals. Phylogenetic analysis of the pre-S/S region and the full-length genomes revealed 54 isolates with HBV/A1 (57%), 21 with HBV/A2 (22%), 19 with HBV/E (20%), and one with HBV/D (1%). HBV genotypes and subgenotypes were unequally distributed through the islands. In São Vicente, the main northern island, most isolates (84%) belonged to the African-originated HBV/A1, with the remaining isolates belonging to HBV/A2, which is prevalent in Europe. Interestingly, the HBV/A1 isolates from São Vicente were closely related to Brazilian sequences into the Asian-American clade, which suggests the dissemination of common African ancestors through slave trade. In contrast, in Santiago and nearby southern islands, where a recent influx from different populations circulates, a higher diversity of HBV was observed: HBV/A1 (40%); HBV/E (32%); HBV/A2 (28%); and HBV/D (1%). HBV/E is a recent genotype disseminated in Africa that was absent in the era of the slave trade. African and European human flows at different times of the history may explain the HBV diversity in Cape Verde. The possible origin and specifics of each HBV genotype circulating in Cape Verde are discussed. PMID:29447232

Hepatitis B virus genotypes A1, A2 and E in Cape Verde: Unequal distribution through the islands and association with human flows.

PubMed

de Pina-Araujo, Isabel Inês M; Spitz, Natalia; Soares, Caroline C; Niel, Christian; Lago, Barbara V; Gomes, Selma A

2018-01-01

Hepatitis B virus (HBV) diversity has not been previously studied in Cape Verde. The archipelago was discovered in 1460 by Portuguese explorers, who brought African slaves to colonise the islands. In this study, we investigated the HBV characteristics from 183 HBsAg-positive Cape Verdean individuals. Phylogenetic analysis of the pre-S/S region and the full-length genomes revealed 54 isolates with HBV/A1 (57%), 21 with HBV/A2 (22%), 19 with HBV/E (20%), and one with HBV/D (1%). HBV genotypes and subgenotypes were unequally distributed through the islands. In São Vicente, the main northern island, most isolates (84%) belonged to the African-originated HBV/A1, with the remaining isolates belonging to HBV/A2, which is prevalent in Europe. Interestingly, the HBV/A1 isolates from São Vicente were closely related to Brazilian sequences into the Asian-American clade, which suggests the dissemination of common African ancestors through slave trade. In contrast, in Santiago and nearby southern islands, where a recent influx from different populations circulates, a higher diversity of HBV was observed: HBV/A1 (40%); HBV/E (32%); HBV/A2 (28%); and HBV/D (1%). HBV/E is a recent genotype disseminated in Africa that was absent in the era of the slave trade. African and European human flows at different times of the history may explain the HBV diversity in Cape Verde. The possible origin and specifics of each HBV genotype circulating in Cape Verde are discussed.

Cape Canaveral Air Force Station, Launch Complex 39, The Solid ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Cape Canaveral Air Force Station, Launch Complex 39, The Solid Rocket Booster Assembly and Refurbishment Facility Manufacturing Building, Southeast corner of Schwartz Road and Contractors Road, Cape Canaveral, Brevard County, FL

DETAIL VIEW OF COMPUTER PANELS, ROOM 8A Cape Canaveral ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL VIEW OF COMPUTER PANELS, ROOM 8A - Cape Canaveral Air Force Station, Launch Complex 39, Mobile Launcher Platforms, Launcher Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

Incidence of neuropsychiatric side effects of efavirenz in HIV-positive treatment-naïve patients in public-sector clinics in the Eastern Cape.

PubMed

Gaida, Razia; Truter, Ilse; Grobler, Christoffel

2016-01-01

It is acknowledged that almost half of patients initiated on efavirenz will experience at least one neuropsychiatric side effect. The aim was to determine the incidence and severity of neuropsychiatric side effects associated with efavirenz use in five public-sector primary healthcare clinics in the Eastern Cape. The study was a prospective drug utilisation study. A total of 126 medical records were reviewed to obtain the required information. After baseline assessment, follow-up reviews were conducted at 4 weeks, 12 weeks and 24 weeks from 2014 to 2015. The participant group was 74.60% female ( n = 94), and the average age was 37.57±10.60 years. There were no neuropsychiatric side effects recorded for any patient. After the full follow-up period, there were a total of 49 non-adherent patients and one patient had demised. A non-adherent patient was defined as a patient who did not return to the clinic for follow-up assessment and medication refills 30 days or more after the appointed date. Some patients ( n = 11) had sent a third party to the clinic to collect their antiretroviral therapy (ART). The clinic pharmacy would at times dispense a two-month supply of medication resulting in the patient presenting only every two months. Further pharmacovigilance studies need to be conducted to determine the true incidence of these side effects. Healthcare staff must be encouraged to keep complete records to ensure meaningful patient assessments. Patients being initiated on ART need to personally attend the clinic monthly for at least the first 6 months of treatment. Clinic staff should receive regular training concerning ART, including changes made to guidelines as well as reminders of side effects experienced.

Species-rich and polyploid-poor: Insights into the evolutionary role of whole-genome duplication from the Cape flora biodiversity hotspot.

PubMed

Oberlander, Kenneth C; Dreyer, Léanne L; Goldblatt, Peter; Suda, Jan; Linder, H Peter

2016-07-01

Whole-genome duplication (WGD) in angiosperms has been hypothesized to be advantageous in unstable environments and/or to increase diversification rates, leading to radiations. Under the first hypothesis, floras in stable environments are predicted to have lower proportions of polyploids than highly, recently disturbed floras, whereas species-rich floras would be expected to have higher than expected proportions of polyploids under the second. The South African Cape flora is used to discriminate between these two hypotheses because it features a hyperdiverse flora predominantly generated by a limited number of radiations (Cape clades), against a backdrop of climatic and geological stability. We compiled all known chromosome counts for species in 21 clades present in the Cape (1653 species, including 24 Cape clades), inferred ploidy levels for these species by inspection or derived from the primary literature, and compared Cape to non-Cape ploidy levels in these clades (17,520 species) using G tests. The Cape flora has anomalously low proportions of polyploids compared with global levels. This pattern is consistently observed across nearly half the clades and across global latitudinal gradients, although individual lineages seem to be following different paths to low levels of WGD and to differing degrees. This pattern shows that the diversity of the Cape flora is the outcome of primarily diploid radiations and supports the hypothesis that WGD may be rare in stable environments. © 2016 Botanical Society of America.

Populations, productivity, and feeding habits of seabirds at Cape Thompson, Alaska: Final report

USGS Publications Warehouse

Fadely, Brian S.; Piatt, John F.; Hatch, Scott A.; Roseneau, David G.

1989-01-01

Investigations of seabird population sizes and breeding biology were conducted at Cape Thompson from 1959 to 1961 during pre-development studies associated with the Atomic through 1982, the Alaskan Program (OCSEAP) supported determine whether changes Energy Commission’s “Project Chariot.” From 1976 Outer Continental Shelf Environmental Assessment efforts to recensus seabirds at Cape Thompson and had occurred since the 1959-61 period. Prior to the present study, it had been 6 years since the last efforts to census seabird colonies in this area.We established a field camp at the and occupied it continuously until 31 were selected for cliff nesting species comprising the Cape Thompson complex, mouth of Ikijaktusak Creek on 2 July August 1988. Permanent study plots in four of the five discrete colonies and regular observations were made throughout the study to document attendance patterns, breeding phenology, and success of murres and kittiwakes. Periodic collections of adults offshore were used to determine the food habits of study species. Shore-based work was supplemented with offshore studies of seabird foraging from the USFWS vessel Eagle-Tiglax, 24-31 August (Fig. 2).Correlation analysis revealed negative trends in murre attendance at all Cape Thompson colonies between 1960 and 1982 or 1988, significantly so for 3 of the 5 colonies. Based on apparent changes in species composition within the colonies, Common Murres declined at a more rapid rate than Thick-billed Murres between 1960 and 1988. Combining information from all colonies, it appears that murre populations have been relatively stable since about 1979. In contrast to murres, the kittiwake population showed no significant trends between 1960 and 1982 or between 1960 and 1988. All fluctuations in kittiwake numbers documented between years were within the variability expected within years. Breeding productivity of murres was about average during 1988 (0.47 young/pair), whereas the productivity of kittiwakes was very poor (0.15 young/pair).Murres and kittiwakes fed mostly on arctic cod and sand lance distributed widely but in low concentrations (e.g., 0.1-10 g/m3) UP to 1.20 km north and northwest of Cape Thompson. In the total area surveyed (225 km2), only two major feeding aggregations were observed where fish school densities exceeded 15 g/ins. Forage fish densities were higher in shallow Alaska Coastal Current waters than offshore in Bering Sea waters, and piscivorous seabirds like murres and kittiwakes fed mostly in coastal waters. Reduced numbers of fish in murre and kittiwake stomachs in August and low breeding success of kittiwakes suggested that forage fish densities observed around Cape Thompson in late August were sufficient to sustain murres but were insufficient for, or inaccessible to, kittiwakes.The breeding failure of Black-legged Kittiwakes at Cape Thompson in 1988 was part throughout causes of kittiwakes of a pervasive syndrome of failure in this species observed the Bering/Chukchi seas and Gulf of Alaska in recent years. The recurrent widespread breeding failure need to be identified if are to have a role in area-wide population monitoring during the period of Alaskan OCS development by the oil and gas industry.The system of land-based plots established in 1988 is recommended for future population monitoring of cliff-nesting birds at Cape Thompson. Based on the coefficients of variation among counts observed in this study, it is estimated that 10 replicate counts per year would detect an 8% change in numbers of Thick-billed Murres between years and a 12% change in Common Murres, with 75% certainty of statistical significance at the 0.05 level. Similarly, a 9% annual change in the population of Black-legged Kittiwakes should be detectable at the 0.05 significance level given samples of 10 replicate counts of the land-based plots.

Review of the physical oceanography of the Cape Hatteras, North Carolina Region. Volume 1. Literature synthesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, C.E.; Berger, T.J.; Boicourt, W.C.

The present study is part of a sequence of programs designed to provide the MMS with a basis for evaluating the potential environmental impacts of oil and gas production off of the Cape Hatteras region. The primary objective of this review is to summarize and critique the present state of knowledge of the physical oceanography of the complex region offshore of Cape Hatteras, North Carolina, within the context of understanding the regional circulation and its relation to the fate of any discharges resulting from offshore oil and gas activity. The two other related objectives are to produce an annotated bibliographymore » of the pertinent literature, primarily from 1970 to the present, and to identify relevant oceanographic data sets which can provide a basis for an improved understanding of circulation patterns and physical oceanographic conditions in the study area.« less

Dynamics and Predictability of Hurricane Humberto (2007) Revealed from Ensemble Analysis and Forecasting

NASA Technical Reports Server (NTRS)

Sippel, Jason A.; Zhang, Fuqing

2009-01-01

This study uses short-range ensemble forecasts initialized with an Ensemble-Kalman filter to study the dynamics and predictability of Hurricane Humberto, which made landfall along the Texas coast in 2007. Statistical correlation is used to determine why some ensemble members strengthen the incipient low into a hurricane and others do not. It is found that deep moisture and high convective available potential energy (CAPE) are two of the most important factors for the genesis of Humberto. Variations in CAPE result in as much difference (ensemble spread) in the final hurricane intensity as do variations in deep moisture. CAPE differences here are related to the interaction between the cyclone and a nearby front, which tends to stabilize the lower troposphere in the vicinity of the circulation center. This subsequently weakens convection and slows genesis. Eventually the wind-induced surface heat exchange mechanism and differences in landfall time result in even larger ensemble spread. 1

Ambient carbon monoxide and daily mortality in three Chinese cities: the China Air Pollution and Health Effects Study (CAPES).

PubMed

Chen, Renjie; Pan, Guowei; Zhang, Yanping; Xu, Qun; Zeng, Guang; Xu, Xiaohui; Chen, Bingheng; Kan, Haidong

2011-11-01

Ambient carbon monoxide (CO) is an air pollutant primarily generated by traffic. CO has been associated with increased mortality and morbidity in developed countries, but few studies have been conducted in Asian developing countries. In the China Air Pollution and Health Effects Study (CAPES), the short-term associations between ambient CO and daily mortality were examined in three Chinese cities: Shanghai, Anshan and Taiyuan. Poisson regression models incorporating natural spline smoothing functions were used to adjust for long-term and seasonal trend of mortality, as well as other time-varying covariates. Effect estimates were obtained for each city and then for the cities combined. In both individual-city and combined analysis, significant associations of CO with both total non-accidental and cardiovascular mortality were observed. In the combined analysis, a 1 mg/m(3) increase of 2-day moving average concentrations of CO corresponded to 2.89% (95%CI: 1.68, 4.11) and 4.17% (95%CI: 2.66, 5.68) increase of total and cardiovascular mortality, respectively. CO was not significantly associated with respiratory mortality. Sensitivity analyses showed that our findings were generally insensitive to alternative model specifications. In conclusion, ambient CO was associated with increased risk of daily mortality in these three cities. Our findings suggest that the role of exposure to CO and other traffic-related air pollutants should be further investigated in China. Copyright © 2011 Elsevier B.V. All rights reserved.

Cubesat Application for Planetary Entry (CAPE) Missions: Micro-Reentry Capsule (MIRCA)

NASA Technical Reports Server (NTRS)

Esper, Jaime

2014-01-01

The Cubesat Application for Planetary Entry Missions (CAPE) concept describes a high-performing Cubesat system which includes a propulsion module and miniaturized technologies capable of surviving atmospheric entry heating, while reliably transmitting scientific and engineering data. The Micro Return Capsule (MIRCA) is CAPEs first planetary entry probe flight prototype. Within this context, this paper briefly describes CAPEs configuration and typical operational scenario, and summarizes ongoing work on the design and basic aerodynamic characteristics of the prototype MIRCA vehicle. CAPE not only opens the door to new planetary mission capabilities, it also offers relatively low-cost opportunities especially suitable to university participation.

Health activism in Cape Town: a case study of the Health Workers Society.

PubMed

Pick, W; Claassen, J W B; Le Grange, C A; Hussey, G D

2012-03-02

The Health Workers Society (HWS), founded in 1980, was one of several progressive health organisations that fought for a democratic health system in South Africa. We document the sociopolitical context within which it operated and some of its achievements. HWS, many of whose members were staff and students of the University of Cape Town (UCT), provided a forum for debate on health-related issues, politics and society, and worked closely with other organisations to oppose the apartheid state's health policies and practices. They assisted with the formation of the first dedicated trade union for all healthcare workers and were one of the first to pioneer the primary healthcare approach in an informal settlement in Cape Town.

KSC-2012-3935

NASA Image and Video Library

2012-07-16

CAPE CANAVERAL, Fla. – At Space Launch Complex 41 at Cape Canaveral Air Force Station, Fla., the Centaur stage has just been mated with the Atlas V rocket, which will launch the Radiation Belt Storm Probes, or RBSP, spacecraft. NASA’s RBSP mission will help us understand the sun’s influence on Earth and near-Earth space by studying the Earth’s radiation belts on various scales of space and time. RBSP will begin its mission of exploration of Earth’s Van Allen radiation belts and the extremes of space weather after its liftoff aboard a United Launch Alliance Atlas V from Cape Canaveral. Liftoff is targeted for Aug. 23, 2012. For more information, visit http://www.nasa.gov/rbsp. Photo credit: NASA/Jim Grossmann

Effects of tannins on fruit selection in three southern African frugivorous birds.

PubMed

Zungu, Manqoba M; Downs, Colleen T

2015-02-01

Tannins are common secondary compounds in plant material and are known for their ability to bind to protein which reduces nitrogen availability in the diet. In fruits, these compounds are responsible for their astringency which is thought to result in reduced food intake. In this study, the repellent effects of tannins were examined in three species of frugivorous birds: red-winged starlings Onychognathus morio, speckled mousebirds Colius striatus and Cape white-eyes Zosterops virens. Birds were fed artificial fruit diets containing varying levels of tannins in paired choice tests with the amount of food eaten by birds used to determine preference. Red-winged starlings were attracted to the control diet, indifferent to the medium tannin diet and deterred by the high tannin diet whereas speckled mousebirds and Cape white-eyes were not deterred at all concentrations. The discrepancy in the results was attributed to differences in taste sensitivity, tolerance levels and detoxification mechanisms of secondary compounds between species. Because fruit selection and ultimately fruit removal rates affect plant community composition, the disparity in the results suggests that frugivorous birds do not contribute equally to plant community dynamics. However, plant secondary compounds in fruits are diverse and their effects are similarly diverse and there is potential that different groups of secondary compounds generate disparate effects. Similar studies on other types of secondary compounds may thus contribute towards a broader understanding of the role of secondary compounds in mediating fruit-frugivore interactions. Copyright © 2014 Elsevier B.V. All rights reserved.

Including Emotional Intelligence in Pharmacy Curricula to Help Achieve CAPE Outcomes

PubMed Central

Fierke, Kerry K.; Sucher, Brandon J.; Janke, Kristin K.

2015-01-01

The importance of emotional intelligence (EI) for effective teamwork and leadership within the workplace is increasingly apparent. As suggested by the 2013 CAPE Outcomes, we recommend that colleges and schools of pharmacy consider EI-related competencies to build self-awareness and professionalism among students. In this Statement, we provide two examples of the introduction of EI into pharmacy curricula. In addition, we provide a 4-phase process based on recommendations developed by EI experts for structuring and planning EI development. Finally, we make 9 recommendations’ to inform the process of including EI in pharmacy curricula. PMID:26089557

KSC-2009-5208

NASA Image and Video Library

2009-09-23

CAPE CANAVERAL, Fla. – Approaching rain clouds at dawn hover over Central Florida's east coast, effectively causing the scrub of the Space Tracking and Surveillance System - Demonstrator spacecraft from Launch Pad 17-B at Cape Canaveral Air Force Station. STSS Demo is a space-based sensor component of a layered Ballistic Missile Defense System designed for the overall mission of detection, tracking and discriminating ballistic missiles. STSS is capable of tracking objects after boost phase and provides trajectory information to other sensors. It will be launched by NASA for the Missile Defense Agency between 8 and 8:58 a.m. EDT Sept. 24. Photo credit: NASA/Jack Pfaller

Effect of Active Learning Techniques on Students' Choice of Approach to Learning in Dentistry: A South African Case Study

ERIC Educational Resources Information Center

Khan, S.

2011-01-01

The purpose of this article is to report on empirical work, related to a techniques module, undertaken with the dental students of the University of the Western Cape, South Africa. I will relate how a range of different active learning techniques (tutorials; question papers and mock tests) assisted students to adopt a deep approach to learning in…

Use of a constucted wetland to reduce nonpoint-source pesticide contamination of the Lourens River, South America

Treesearch

Ralf Schulz

2000-01-01

The Lourens River, Western Cape, South Africa, and its tributaries situated in an intensively cultivated orchard area receive pesticide contamination during rainfall-induced runoff and during spraydrift. A 0.44-ha constructed wetland, built in 1991 in one of the tributaries (summer flow 0.03 m3 per second), was studied in order to assess its effectiveness in reducing...

The admixture structure and genetic variation of the archipelago of Cape Verde and its implications for admixture mapping studies.

PubMed

Beleza, Sandra; Campos, Joana; Lopes, Jailson; Araújo, Isabel Inês; Hoppfer Almada, Ana; Correia e Silva, António; Parra, Esteban J; Rocha, Jorge

2012-01-01

Recently admixed populations offer unique opportunities for studying human history and for elucidating the genetic basis of complex traits that differ in prevalence between human populations. Historical records, classical protein markers, and preliminary genetic data indicate that the Cape Verde islands in West Africa are highly admixed and primarily descended from European males and African females. However, little is known about the variation in admixture levels, admixture dynamics and genetic diversity across the islands, or about the potential of Cape Verde for admixture mapping studies. We have performed a detailed analysis of phenotypic and genetic variation in Cape Verde based on objective skin color measurements, socio-economic status (SES) evaluations and data for 50 autosomal, 34 X-chromosome, and 21 non-recombinant Y-chromosome (NRY) markers in 845 individuals from six islands of the archipelago. We find extensive genetic admixture between European and African ancestral populations (mean West African ancestry = 0.57, sd = 0.08), with individual African ancestry proportions varying considerably among the islands. African ancestry proportions calculated with X and Y-chromosome markers confirm that the pattern of admixture has been sex-biased. The high-resolution NRY-STRs reveal additional patterns of variation among the islands that are most consistent with differentiation after admixture. The differences in the autosomal admixture proportions are clearly evident in the skin color distribution across the islands (Pearson r = 0.54, P-value<2e-16). Despite this strong correlation, there are significant interactions between SES and skin color that are independent of the relationship between skin color and genetic ancestry. The observed distributions of admixture, genetic variation and skin color and the relationship of skin color with SES relate to historical and social events taking place during the settlement history of Cape Verde, and have implications for the design of association studies using this population.

The Admixture Structure and Genetic Variation of the Archipelago of Cape Verde and Its Implications for Admixture Mapping Studies

PubMed Central

Beleza, Sandra; Campos, Joana; Lopes, Jailson; Araújo, Isabel Inês; Hoppfer Almada, Ana; e Silva, António Correia; Parra, Esteban J.; Rocha, Jorge

2012-01-01

Recently admixed populations offer unique opportunities for studying human history and for elucidating the genetic basis of complex traits that differ in prevalence between human populations. Historical records, classical protein markers, and preliminary genetic data indicate that the Cape Verde islands in West Africa are highly admixed and primarily descended from European males and African females. However, little is known about the variation in admixture levels, admixture dynamics and genetic diversity across the islands, or about the potential of Cape Verde for admixture mapping studies. We have performed a detailed analysis of phenotypic and genetic variation in Cape Verde based on objective skin color measurements, socio-economic status (SES) evaluations and data for 50 autosomal, 34 X-chromosome, and 21 non-recombinant Y-chromosome (NRY) markers in 845 individuals from six islands of the archipelago. We find extensive genetic admixture between European and African ancestral populations (mean West African ancestry = 0.57, sd = 0.08), with individual African ancestry proportions varying considerably among the islands. African ancestry proportions calculated with X and Y-chromosome markers confirm that the pattern of admixture has been sex-biased. The high-resolution NRY-STRs reveal additional patterns of variation among the islands that are most consistent with differentiation after admixture. The differences in the autosomal admixture proportions are clearly evident in the skin color distribution across the islands (Pearson r = 0.54, P-value<2e–16). Despite this strong correlation, there are significant interactions between SES and skin color that are independent of the relationship between skin color and genetic ancestry. The observed distributions of admixture, genetic variation and skin color and the relationship of skin color with SES relate to historical and social events taking place during the settlement history of Cape Verde, and have implications for the design of association studies using this population. PMID:23226471

Heat treatment as a universal technical solution for silcrete use? A comparison between silcrete from the Western Cape (South Africa) and the Kalahari (Botswana)

PubMed Central

Nash, David J.; Coulson, Sheila; Göden, Matthias B.; Awcock, Graeme J.

2017-01-01

Heat treatment was one of the first transformative technologies in the southern African Middle Stone Age (MSA), with many studies in the Cape coastal zone of South Africa identifying it as an essential step in the preparation of silcrete prior to its use in stone tool manufacture. To date, however, no studies have investigated whether heat treatment is necessary for all silcrete types, and how geographically widespread heat treatment was in the subcontinent. The aim of this study is to investigate experimentally whether heat treatment continued further north into the Kalahari Desert of Botswana and northernmost South Africa, the closest area with major silcrete outcrops to the Cape. For this we analyse the thermal transformations of silcrete from both regions, proposing a comprehensive model of the chemical, crystallographic and ‘water’-related processes taking place upon heat treatment. For the first time, we also explore the mobility of minor and trace elements during heat treatment and introduce a previously undescribed mechanism—steam leaching—causing depletion of a limited number of elements. The results of this comparative study reveal the Cape and Kalahari silcrete to respond fundamentally differently to heat treatment. While the former can be significantly improved by heat, the latter is deteriorated in terms of knapping quality. These findings have important implications for our understanding of the role of fire as a technical solution in MSA stone tool knapping, and for the extension of its use in southern Africa. Silcrete heat treatment—at least in the form we understand it today—may have been a strictly regional phenomenon, confined to a narrow zone along the west and south coast of the Cape. On the basis of our findings, silcrete heat treatment should not be added as a new trait on the list of behaviours that characterise the MSA of the southern African subcontinent. PMID:28723941

Heat treatment as a universal technical solution for silcrete use? A comparison between silcrete from the Western Cape (South Africa) and the Kalahari (Botswana).

PubMed

Schmidt, Patrick; Nash, David J; Coulson, Sheila; Göden, Matthias B; Awcock, Graeme J

2017-01-01

Heat treatment was one of the first transformative technologies in the southern African Middle Stone Age (MSA), with many studies in the Cape coastal zone of South Africa identifying it as an essential step in the preparation of silcrete prior to its use in stone tool manufacture. To date, however, no studies have investigated whether heat treatment is necessary for all silcrete types, and how geographically widespread heat treatment was in the subcontinent. The aim of this study is to investigate experimentally whether heat treatment continued further north into the Kalahari Desert of Botswana and northernmost South Africa, the closest area with major silcrete outcrops to the Cape. For this we analyse the thermal transformations of silcrete from both regions, proposing a comprehensive model of the chemical, crystallographic and 'water'-related processes taking place upon heat treatment. For the first time, we also explore the mobility of minor and trace elements during heat treatment and introduce a previously undescribed mechanism-steam leaching-causing depletion of a limited number of elements. The results of this comparative study reveal the Cape and Kalahari silcrete to respond fundamentally differently to heat treatment. While the former can be significantly improved by heat, the latter is deteriorated in terms of knapping quality. These findings have important implications for our understanding of the role of fire as a technical solution in MSA stone tool knapping, and for the extension of its use in southern Africa. Silcrete heat treatment-at least in the form we understand it today-may have been a strictly regional phenomenon, confined to a narrow zone along the west and south coast of the Cape. On the basis of our findings, silcrete heat treatment should not be added as a new trait on the list of behaviours that characterise the MSA of the southern African subcontinent.

Selection on overdominant genes maintains heterozygosity along multiple chromosomes in a clonal lineage of honey bee.

PubMed

Goudie, Frances; Allsopp, Michael H; Oldroyd, Benjamin P

2014-01-01

Correlations between fitness and genome-wide heterozygosity (heterozygosity-fitness correlations, HFCs) have been reported across a wide range of taxa. The genetic basis of these correlations is controversial: do they arise from genome-wide inbreeding ("general effects") or the "local effects" of overdominant loci acting in linkage disequilibrium with neutral loci? In an asexual thelytokous lineage of the Cape honey bee (Apis mellifera capensis), the effects of inbreeding have been homogenized across the population, making this an ideal system in which to detect overdominant loci, and to make inferences about the importance of overdominance on HFCs in general. Here we investigate the pattern of zygosity along two chromosomes in 42 workers from the clonal Cape honey bee population. On chromosome III (which contains the sex-locus, a gene that is homozygous-lethal) and chromosome IV we show that the pattern of zygosity is characterized by loss of heterozygosity in short regions followed by the telomeric restoration of heterozygosity. We infer that at least four selectively overdominant genes maintain heterozygosity on chromosome III and three on chromosome IV via local effects acting on neutral markers in linkage disequilibrium. We conclude that heterozygote advantage and local effects may be more common and evolutionarily significant than is generally appreciated. © 2013 The Author(s). Evolution © 2013 The Society for the Study of Evolution.

Surface chemical effects on colloid stability and transport through natural porous media

USGS Publications Warehouse

Puls, Robert W.; Paul, Cynthia J.; Clark, Donald A.

1993-01-01

Surface chemical effects on colloidal stability and transport through porous media were investigated using laboratory column techniques. Approximately 100 nm diameter, spherical, iron oxide particles were synthesized as the mobile colloidal phase. The column packing material was retrieved from a sand and gravel aquifer on Cape Cod, MA. Previous studies have indicated enhanced stability and transport of iron oxide particles due to specific adsorption of some inorganic anions on the iron oxide surface. This phenomenon was further evaluated with an anionic surfactant, sodium dodecyl sulfate. Surfactants constitute a significant mass of the contaminant loading at the Cape Cod site and their presence may contribute to colloidal transport as a significant transport mechanism at the site. Other studies at the site have previously demonstrated the occurrence of this transport mechanism for iron phosphate particles. Photon correlation spectroscopy, micro-electrophoretic mobility, and scanning electron microscopy were used to evaluate particle stability, mobility and size. Adsorption of negatively charged organic and inorganic species onto the surface of the iron oxide particles was shown to significantly enhance particle stability and transport through alterations of the electrokinetic properties of the particle surface. Particle breakthrough generally occurred simultaneously with tritiated water, a conservative tracer. The extent of particle breakthrough was primarily dependent upon colloidal stability and surface charge.

Role of environmental exposures and filaggrin mutations on associations of ethnic origin with risk of childhood eczema. The Generation R Study.

PubMed

Elbert, Niels J; Duijts, Liesbeth; den Dekker, Herman T; Jaddoe, Vincent W V; Sonnenschein-van der Voort, Agnes M M; de Jongste, Johan C; Pasmans, Suzanne G M A

2016-09-01

The prevalence of childhood eczema varies considerably between ethnic groups. However, data from longitudinal studies remain scarce. We examined the associations of ethnic origin with the development of eczema from birth until the age of 4 years, and whether known environmental and genetic risk factors explain these associations. This study was performed in a multiethnic population-based prospective cohort among 5,082 children. Ethnic origin was based on the parents' country of birth. Data on physician-diagnosed eczema were obtained by annual questionnaires. Information on environmental risk factors was mostly obtained by questionnaires. Filaggrin (FLG) mutations (2282del4, R2447X, R501X, and S3247X) were genotyped for 3,096 children. We used generalized estimating equation models to examine the associations of ethnic origin with the longitudinal odds of eczema at 6 months and 1, 2, 3, and 4 years of age overall and independently. Compared with Dutch children, Cape Verdean, Dutch Antillean, Surinamese-Creole, and Surinamese-Hindustani children had overall increased risks of eczema (OR (95%-CI): 1.53 (1.15, 2.03), 1.60 (1.21, 2.12), 1.95 (1.56, 2.44), and 2.06 (1.65, 2.57), respectively). Effect estimates for the associations of Cape Verdean and Dutch Antillean origin with eczema became non-significant after adjustment for genetic risk factors or both environmental and genetic risk factors, respectively. Surinamese-Creole and Surinamese-Hindustani children remained to have increased risks of eczema. Cape Verdean, Dutch Antillean, Surinamese-Creole, and Surinamese-Hindustani children had increased risks of eczema in the first 4 years of life. Environmental and genetic risk factors partly weakened these associations. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The Degradational History of Endeavour Crater, Mars

NASA Technical Reports Server (NTRS)

Grant, J. A.; Parker, T. J.; Crumpler, L. S.; Wilson, S. A.; Golombek, M. P.; Mittlefehldt, D. W.

2015-01-01

Endeavour crater (2.28 deg S, 354.77 deg E) is a Noachian-aged 22 km-diameter impact structure of complex morphology in Meridiani Planum. The degradation state of the crater has been studied using Mars Reconnaissance Orbiter and Opportunity rover data. Exposed rim segments rise approximately 10 m to approximately 100 m above the level of the embaying Burns Formation and the crater is 200-500 m deep with the southern interior wall exposing over approximately 300 m relief. Both pre-impact rocks (Matijevic Formation) and Endeavour impact ejecta (Shoemaker Formation) are present at Cape York, but only the Shoemaker crops out (up to approximately 140 m) along the rim segment from Murray Ridge to Cape Tribulation. Study of pristine complex craters Bopolu and Tooting, and morphometry of other martian complex craters, enables us to approximate Endeavour's pristine form. The original rim likely averaged 410 m (+/-)200 m in elevation and a 250-275 m section of ejecta ((+/-)50-60 m) would have composed a significant fraction of the rim height. The original crater depth was likely between 1.5 km and 2.2 km. Comparison between the predicted original and current form of Endeavour suggests approximately 100-200 m rim lowering that removed most ejecta in some locales (e.g., Cape York) while thick sections remain elsewhere (e.g., Cape Tribulation). Almost complete removal of ejecta at Cape York and minimal observable offset across fractures indicates current differences in rim relief are not solely due to original rim relief. Rim segments are embayed by approximately 100-200 m thickness of plains rocks outside the crater, but thicker deposits lie inside the crater. Ventifact textures confirm ongoing eolian erosion with the overall extent difficult to estimate. Analogy with degraded Noachian-aged craters south of Endeavour, however, suggests fluvial erosion dominated rim degradation in the Noachian and was likely followed by approximately 10s of meters modification by alternate processes. Such degradation is consistent with 1) the interpretation of a pediment on the rim flanks of Endeavour, 2) the formation of features such as Marathon Valley, 3) the nearly complete removal of ejecta at Cape York, 4) preservation of a thicker section of ejecta at Cape Tribulation and perhaps, 5) the origin of some gaps in the rim around the crater. A paucity of debris shed from the rim indicates most degradation occurred prior to embayment by the plains rocks.

An Investigation into the Impact of School Context on Achievement: A Situational Analysis of Five Western Cape Schools in South Africa

ERIC Educational Resources Information Center

Mushayikwa, Emmanuel

2009-01-01

The purpose of this study was to generate a snapshot profile of the teaching and learning environment in each of five schools in Cape Town, South Africa. The generated profile would in turn facilitate the identification of critical, localized and systemic factors that might be targeted by a whole school intervention programme to improve the…

The Impact of Computer and Mathematics Software Usage on Performance of School Leavers in the Western Cape Province of South Africa: A Comparative Analysis

ERIC Educational Resources Information Center

Smith, Garth Spencer; Hardman, Joanne

2014-01-01

In this study the impact of computer immersion on performance of school leavers Senior Certificate mathematics scores was investigated across 31 schools in the EMDC East education district of Cape Town, South Africa by comparing performance between two groups: a control and an experimental group. The experimental group (14 high schools) had access…

A situational analysis of training for behaviour change counselling for primary care providers, South Africa.

PubMed

Malan, Zelra; Mash, Bob; Everett-Murphy, Katherine

2015-03-18

Non-communicable diseases and associated risk factors (smoking, alcohol abuse, physical inactivity and unhealthy diet) are a major contributor to primary care morbidity and the burden of disease. The need for healthcare-provider training in evidence-based lifestyle interventions has been acknowledged by the National Department of Health. However, local studies suggest that counselling on lifestyle modification from healthcare providers is inadequate and this may, in part, be attributable to a lack of training. This study aimed to assess the current training courses for primary healthcare providers in the Western Cape. Stellenbosch University and University of Cape Town. Qualitative interviews were conducted with six key informants (trainers of primary care nurses and registrars in family medicine) and two focus groups (nine nurses and eight doctors) from both Stellenbosch University and the University of Cape Town. Trainers lack confidence in the effectiveness of behaviour change counselling and in current approaches to training. Current training is limited by time constraints and is not integrated throughout the curriculum--there is a focus on theory rather than modelling and practice, as well as a lack of both formative and summative assessment. Implementation of training is limited by a lack of patient education materials, poor continuity of care and record keeping, conflicting lifestyle messages and an unsupportive organisational culture. Revising the approach to current training is necessary in order to improve primary care providers' behaviour change counselling skills. Primary care facilities need to create a more conducive environment that is supportive of behaviour change counselling.

Household and community income, economic shocks and risky sexual behavior of young adults: evidence from the Cape Area Panel Study 2002 and 2005.

PubMed

Dinkelman, Taryn; Lam, David; Leibbrandt, Murray

2007-11-01

To describe recent trends in adolescent sexual behavior in Cape Town, South Africa, and to determine whether household and community poverty and negative economic shocks predict risky sexual behavior. Matched survey data on 2993 African and coloured youth from the Cape Area Panel Study 2002 and 2005. Sexual debut, multiple sexual partners in past year, condom use at last sex, measured in 2002 and 2005. We tested for changes over time in reported sexual behavior and estimate multivariate probit models to measure the association between 2002 individual, household and community characteristics and 2005 sexual behavior. There was a statistically significant increase in condom use and a decrease in the incidence of multiple sexual partners between 2002 and 2005 for young women aged 17-22 years. Young women in households with 10% higher income were 0.53% less likely to debut sexually by 2005; young men in communities with a 10% higher poverty rate were 5% less likely to report condom use at last sex. Negative economic shocks are associated with a 0.04% increase in the probability of multiple partnerships for young women. Education is positively correlated with sexual debut for young women and with multiple partnerships for both sexes. Trends in sexual behavior between 2002 and 2005 indicate significant shifts towards safer practices. There is little evidence of a relationship between negative economic shocks, household and community poverty, and risky behavior. We hypothesize that the unexpected positive relationship between education and sexual debut may be driven by peer effects in schools with substantial age mixing.

A situational analysis of training for behaviour change counselling for primary care providers, South Africa

PubMed Central

Mash, Bob; Everett-Murphy, Katherine

2015-01-01

Abstract Background Non-communicable diseases and associated risk factors (smoking, alcohol abuse, physical inactivity and unhealthy diet) are a major contributor to primary care morbidity and the burden of disease. The need for healthcare-provider training in evidence-based lifestyle interventions has been acknowledged by the National Department of Health. However, local studies suggest that counselling on lifestyle modification from healthcare providers is inadequate and this may, in part, be attributable to a lack of training. Aim This study aimed to assess the current training courses for primary healthcare providers in the Western Cape. Setting Stellenbosch University and University of Cape Town. Methods Qualitative interviews were conducted with six key informants (trainers of primary care nurses and registrars in family medicine) and two focus groups (nine nurses and eight doctors) from both Stellenbosch University and the University of Cape Town. Results Trainers lack confidence in the effectiveness of behaviour change counselling and in current approaches to training. Current training is limited by time constraints and is not integrated throughout the curriculum – there is a focus on theory rather than modelling and practice, as well as a lack of both formative and summative assessment. Implementation of training is limited by a lack of patient education materials, poor continuity of care and record keeping, conflicting lifestyle messages and an unsupportive organisational culture. Conclusion Revising the approach to current training is necessary in order to improve primary care providers’ behaviour change counselling skills. Primary care facilities need to create a more conducive environment that is supportive of behaviour change counselling. PMID:26245589

Gender-based Violence and HIV Sexual Risk Behavior: Alcohol Use and Mental Health Problems as Mediators among Women in Drinking Venues, Cape Town

PubMed Central

Pitpitan, Eileen V.; Kalichman, Seth C.; Eaton, Lisa A.; Sikkema, Kathleen J.; Watt, Melissa H.; Skinner, Donald

2012-01-01

Gender-based violence is a key determinant of HIV infection among women in South Africa as elsewhere. However, research has not examined potential mediating processes to explain the link between experiencing abuse and engaging in HIV sexual risk behavior. Previous studies suggest that alcohol use and mental health problems may explain how gender-based violence predicts sexual risk. In a prospective study, we examined whether lifetime history of gender-based violence indirectly affects future sexual risk behavior through alcohol use, depression and post-traumatic stress disorder (PTSD) in a high-risk socio-environmental context. We recruited a cohort of 560 women from alcohol drinking venues in a Cape Town, South African township. Participants completed computerized interviews at baseline and 4 months later. We tested prospective mediating associations between gender-based violence, alcohol use, depression, PTSD, and sexual risk behavior. There was a significant indirect effect of gender-based violence on sexual risk behavior through alcohol use, but not mental health problems. Women who were physically and sexually abused drank more, which in turn predicted more unprotected sex. We did not find a mediated relationship between alcohol use and sexual risk behavior through the experience of recent abuse or mental health problems. Alcohol use explains the link between gender-based violence and sexual risk behavior among women attending drinking venues in Cape Town, South Africa. Efforts to reduce HIV risk in South Africa by addressing gender-based violence must also address alcohol use. PMID:22832324

Gender-based violence and HIV sexual risk behavior: alcohol use and mental health problems as mediators among women in drinking venues, Cape Town.

PubMed

Pitpitan, Eileen V; Kalichman, Seth C; Eaton, Lisa A; Sikkema, Kathleen J; Watt, Melissa H; Skinner, Donald

2012-10-01

Gender-based violence is a key determinant of HIV infection among women in South Africa as elsewhere. However, research has not examined potential mediating processes to explain the link between experiencing abuse and engaging in HIV sexual risk behavior. Previous studies suggest that alcohol use and mental health problems may explain how gender-based violence predicts sexual risk. In a prospective study, we examined whether lifetime history of gender-based violence indirectly affects future sexual risk behavior through alcohol use, depression and post-traumatic stress disorder (PTSD) in a high-risk socio-environmental context. We recruited a cohort of 560 women from alcohol drinking venues in a Cape Town, South African township. Participants completed computerized interviews at baseline and 4 months later. We tested prospective mediating associations between gender-based violence, alcohol use, depression, PTSD, and sexual risk behavior. There was a significant indirect effect of gender-based violence on sexual risk behavior through alcohol use, but not mental health problems. Women who were physically and sexually abused drank more, which in turn predicted more unprotected sex. We did not find a mediated relationship between alcohol use and sexual risk behavior through the experience of recent abuse or mental health problems. Alcohol use explains the link between gender-based violence and sexual risk behavior among women attending drinking venues in Cape Town, South Africa. Efforts to reduce HIV risk in South Africa by addressing gender-based violence must also address alcohol use. Copyright © 2012 Elsevier Ltd. All rights reserved.

A review of antimalarial plants used in traditional medicine in communities in Portuguese-speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola.

PubMed

Silva, Jefferson Rocha de A; Ramos, Aline de S; Machado, Marta; de Moura, Dominique F; Neto, Zoraima; Canto-Cavalheiro, Marilene M; Figueiredo, Paula; do Rosário, Virgilio E; Amaral, Ana Claudia F; Lopes, Dinora

2011-08-01

The isolation of bioactive compounds from medicinal plants, based on traditional use or ethnomedical data, is a highly promising potential approach for identifying new and effective antimalarial drug candidates. The purpose of this review was to create a compilation of the phytochemical studies on medicinal plants used to treat malaria in traditional medicine from the Community of Portuguese-Speaking Countries (CPSC): Angola, Brazil, Cape Verde, Guinea-Bissau, Mozambique and São Tomé and Príncipe. In addition, this review aimed to show that there are several medicinal plants popularly used in these countries for which few scientific studies are available. The primary approach compared the antimalarial activity of native species used in each country with its extracts, fractions and isolated substances. In this context, data shown here could be a tool to help researchers from these regions establish a scientific and technical network on the subject for the CPSC where malaria is a public health problem.

Geological Interpretation of Bathymetric and Backscatter Imagery of the Sea Floor off Eastern Cape Cod, Massachusetts

USGS Publications Warehouse

Poppe, Larry J.; Paskevich, Valerie F.; Butman, Bradford; Ackerman, Seth D.; Danforth, William W.; Foster, Dave S.; Blackwood, Dann S.

2006-01-01

The imagery, interpretive data layers, and data presented herein were derived from multibeam echo-sounder data collected off Eastern Cape Cod, Massachusetts, and from the stations occupied to verify these acoustic data. The basic data layers show sea-floor topography, sun-illuminated shaded relief, and backscatter intensity; interpretive layers show the distributions of surficial sediment and sedimentary environments. Presented verification data include new and historical sediment grain-size analyses and a gallery of still photographs of the seabed. The multibeam data, which cover a narrow band of the sea floor extending from Provincetown around the northern tip of Cape Cod and south southeastward to off Monomoy Island, were collected during transits between concurrent mapping projects in the Stellwagen Bank National Marine Sanctuary (Valentine and others, 2001; Butman and others, 2004; and Valentine, 2005) and Great South Channel (Valentine and others, 2003a, b, c, d). Although originally collected to maximize the use of time aboard ship, these data provide a fundamental framework for research and management activities in this part of the Gulf of Maine (Noji and others, 2004), show the composition and terrain of the seabed, and provide information on sediment transport and benthic habitat. These data and interpretations also support ongoing modeling studies of the lower Cape's aquifer system (Masterson, 2004) and of erosional hotspots along the Cape Cod National Seashore (List and others, 2006).

Cape Cod

Atmospheric Science Data Center

2014-05-15

... 3000 shipwrecks on the Cape, mainly along the treacherous outer shore between Provincetown located at the "fist" of the Cape and Chatham ... D.C. The Terra spacecraft is managed by NASA's Goddard Space Flight Center, Greenbelt, MD. The MISR data were obtained from the NASA ...

Cape Cod National Seashore intelligent transportation systems implementation plan: final report

DOT National Transportation Integrated Search

2011-03-18

The Volpe National Transportation Systems Center (Volpe Center) is providing technical support to the Cape Cod National Seashore in the planning of an Intelligent Transportation System (ITS). In collaboration with the Cape Cod Commission, National Se...

Cost and cost-effectiveness of community-based care for tuberculosis in Cape Town, South Africa.

PubMed

Sinanovic, E; Floyd, K; Dudley, L; Azevedo, V; Grant, R; Maher, D

2003-09-01

Guguletu and Nyanga areas of Cape Town, South Africa. To evaluate the affordability and cost-effectiveness of community involvement in tuberculosis (TB) care. A cost-effectiveness analysis comparing treatment for new smear-positive pulmonary and retreatment TB patients in two similar townships, one providing clinic-based-care with community-based observation options available for its TB patients (Guguletu) and one providing clinic-based care only, with no community-based observation of treatment (Nyanga). Costs were assessed from a societal perspective in 1997 US dollars, and cost-effectiveness was calculated as the cost per patient successfully treated. TB treatment in Guguletu was more cost-effective than TB treatment in Nyanga for both new and retreatment patients (dollars 726 vs. dollars 1201 and dollars 1419 vs. dollars 2058, respectively). This reflected both lower costs (dollars 495 vs. dollars 769 per patient treated for new cases; dollars 823 vs. dollars 1070 per patient treated for retreatment cases) and better treatment outcomes (successful treatment rate 68% vs. 64% and 58% vs. 52% for new and retreatment patients, respectively). Within Guguletu, community-based care was more than twice as cost-effective as clinic-based care (dollars 392 vs. dollars 1302 per patient successfully treated for new patients, and dollars 766 vs. dollars 2008 for retreatment patients), for similar reasons (e.g., for new cases, dollars 314 vs. dollars 703 per patient treated, successful treatment rate 80% vs. 54%). Community involvement in TB care can improve the affordability and cost-effectiveness of TB treatment in urban South Africa. Expansion in the Western Cape and in similar areas of the country is worthy of serious consideration by planners and policy-makers.

The role of beetle marks and flower colour on visitation by monkey beetles (hopliini) in the greater cape floral region, South Africa.

PubMed

Van Kleunen, Mark; Nänni, Ingrid; Donaldson, John S; Manning, John C

2007-12-01

A deviation from the classical beetle pollination syndrome of dull-coloured flowers with an unpleasant scent is found in the Greater Cape Floral Region of South Africa. Here, monkey beetles (Scarabaeidae) visit brightly coloured, odourless flowers with conspicuous dark spots and centres (beetle marks). The role of flower colour and markings in attracting monkey beetles is still poorly understood. Artificial model flowers with different marking patterns were used to test the effect of beetle marks on visitation by monkey beetles. To test whether monkey beetles are conditioned to the colour of the local matrix species, model flowers of different colours were placed in populations of three differently coloured species of Iridaceae. Among all three matrix species the presence of dark markings of some kind (either centres or spots) increased visitation rates but the different matrix species differed in whether the effect was due to a dark centre or to dark spots. Monkey beetles were not conditioned for the colour of the matrix species: model colour was not significant in the Hesperantha vaginata and in the Romulea monadelpha matrices, whereas yellow model flowers were preferred over orange ones in the orange-flowered Sparaxis elegans matrix. This study is the first to demonstrate that beetle marks attract pollinating monkey beetles in the Greater Cape Floral Region. In contrast to plants with the classical beetle pollination syndrome that use floral scent as the most important attractant of pollinating beetles, plants with the monkey beetle pollination syndrome rely on visual signals, and, in some areas at least, monkey beetles favour flowers with dark beetle markings over unmarked flowers.

Mantacaprella macaronensis, a new genus and species of Caprellidae (Crustacea: Amphipoda) from Canary Islands and Cape Verde.

PubMed

Maite, Vázquez-Luis; José M, Guerra-García; Susana, Carvalho; Lydia Png-Gonzalez

2013-01-01

Mantacaprella macaronensis new genus, new species, is described based on specimens collected from Canary Islands and Cape Verde. Mantacaprella is close to the genera Parambus, Pseudolirius, Propodalirius and Paracaprella, but can be distinguished by the combination of the following characteristics: pereopods 3, 4 and 5 two-articulate; pereopods 6 and 7 six-articulate; mandibular molar present and palp absent; male abdomen with a pair of well-developed appendages. The new species has been found living in Cymodocea nodosa meadows and Caulerpa prolifera beds from 8.8 to 14.6 m depth in Gran Canaria (Canary Islands), and in natural rocky and artificial habitats (shipwrecks) at 25 m in Sal Island (Cape Verde). Even though the new species is one of the dominant amphipods inhabiting meadows of Cymodocea nodosa in Gran Canaria and in Cape Verde, it had not been described so far. This reflects the lack of knowledge on Macaronesian invertebrates, such as amphipods, and the need of further taxonomical studies to better characterise the whole biodiversity of this region and to design adequate programmes of management and conservation.

Characterization of the genome of a novel ilarvirus naturally infecting Cape gooseberry (Physalis peruviana).

PubMed

Gallo-García, Yuliana M; Jaramillo-Mesa, Helena; Toro-Fernández, Luisa F; Marín-Montoya, Mauricio; Gutiérrez, Pablo A

2018-06-01

As part of an initiative to characterize viruses infecting Cape gooseberry in the province of Antioquia (Colombia), we report the genome sequence of a new member of the genus Ilarvirus (family Bromoviridae). This virus was identified in a Cape gooseberry plot in the municipality of Marinilla in a mixed infection with potato virus Y (PVY) as part of high-throughput sequencing initiative. Results were confirmed by nested RT-PCR and DAS-ELISA. Phylogenetic analysis suggested that the Cape gooseberry ilarvirus is a new member of subgroup 1 and it is most closely related to ageratum latent virus (AgLV). The name "Cape gooseberry ilarvirus 1" (CGIV-1) is proposed for this new ilarvirus.

Translational Research in South Africa: Evaluating Implementation Quality Using a Factorial Design

PubMed Central

Smith, Edward A.; Collins, Linda M.; Graham, John W.; Lai, Mary; Wegner, Lisa; Vergnani, Tania; Matthews, Catherine; Jacobs, Joachim

2012-01-01

Background HealthWise South Africa: Life Skills for Adolescents (HW) is an evidence-based substance use and sexual risk prevention program that emphasizes the positive use of leisure time. Since 2000, this program has evolved from pilot testing through an efficacy trial involving over 7,000 youth in the Cape Town area. Beginning in 2011, through 2015, we are undertaking a new study that expands HW to all schools in the Metro South Education District. Objective This paper describes a research study designed in partnership with our South African collaborators that examines three factors hypothesized to affect the quality and fidelity of HW implementation: enhanced teacher training; teacher support, structure and supervision; and enhanced school environment. Methods Teachers and students from 56 schools in the Cape Town area will participate in this study. Teacher observations are the primary means of collecting data on factors affecting implementation quality. These factors address the practical concerns of teachers and schools related to likelihood of use and cost-effectiveness, and are hypothesized to be “active ingredients” related to high-quality program implementation in real-world settings. An innovative factorial experimental design was chosen to enable estimation of the individual effect of each of the three factors. Results Because this paper describes the conceptualization of our study, results are not yet available. Conclusions The results of this study may have both substantive and methodological implications for advancing Type 2 translational research. PMID:22707870

Panorama from 'Cape Verde' (False Color)

NASA Technical Reports Server (NTRS)

2007-01-01

NASA's Mars Exploration Rover Opportunity captured this vista of 'Victoria Crater' from the viewpoint of 'Cape Verde,' one of the promontories that are part of the scalloped rim of the crater. Opportunity drove onto Cape Verde shortly after arriving at the rim of Victoria in September 2006. The view combines hundreds of exposures taken by the rover's panoramic camera (Pancam). The camera began taking the component images during Opportunity's 970th Martian day, or sol, on Mars (Oct. 16, 2006). Work on the panorama continued through the solar conjunction period, when Mars was nearly behind the sun from Earth's perspective and communications were minimized. Acquisition of images for this panorama was completed on Opportunity's 991st sol (Nov. 7, 2006).

The top of Cape Verde is in the immediate foreground at the center of the image. To the left and right are two of the more gradually sloped bays that alternate with the cliff-faced capes or promontories around the rim of the crater. 'Duck Bay,' where Opportunity first reached the rim, is to the right. Beyond Duck Bay counterclockwise around the rim, the next promontory is 'Cabo Frio,' about 150 meters (500 feet) from the rover. On the left side of the panorama is 'Cape St. Mary,' the next promontory clockwise from Cape Verde and about 40 meters (130 feet) from the rover. The vantage point atop Cape Verde offered a good view of the rock layers in the cliff face of Cape St. Mary, which is about 15 meters or 50 feet tall. By about two weeks after the Pancam finished collecting the images for this panorama, Opportunity had driven to Cape St. Mary and was photographing Cape Verde's rock layers.

The far side of the crater lies about 800 meters (half a mile) away, toward the southeast.

This view combines images taken through three of the Pancam's filters, admitting light with wavelengths centered at 750 nanometers (near infrared), 530 nanometers (green) and 430 nanometers (violet). It is presented in false color to emphasize differences among materials in the rocks and soils.

Results of a cluster randomised controlled trial to reduce risky use of alcohol, alcohol-related HIV risks and improve help-seeking behaviour among safety and security employees in the Western Cape, South Africa.

PubMed

Burnhams, Nadine Harker; London, Leslie; Laubscher, Ria; Nel, Elmarie; Parry, Charles

2015-05-08

To test the effectiveness of a programme aimed at reducing the risky use of alcohol and alcohol-related HIV risk and increase help-seeking behaviour among a sample of municipal employees in the Western Cape Province, South Africa. A clustered randomised controlled trial was conducted in 2011-2012 among 325 employees. The eight hour intervention, Team Awareness (TA), addressing behavioural risk among employees was administered to 168 employees in the intervention arm and the 157 employees in the control arm who received a one-hour wellness talk. The results show that TA had the greatest impact on risky drinking practices and hangover effects. There was a significant group × time interaction (F (1, 117) = 25.16, p<0.0001) with participants in the intervention condition reducing number of days on which they engaged in binge drinking. There was also a significant time effect with participants in the intervention condition reducing the likelihood of going to work with a hangover (F (1,117) = 4.10, p=0.045). No reduction in HIV-related risk behaviours were found. This intervention study was able to demonstrate a modest but significant reduction in risky drinking practices and hangover effects. This provides encouraging evidence for the effectiveness of interventions that address risky use of alcohol among employed persons, further providing a launch pad for strengthening and replicating future RCT studies on workplace prevention, especially in developing country settings. Pan-African Control Trial Registry (201301000458308) .

Lessons learned about collaborative evaluation using the Capacity for Applying Project Evaluation (CAPE) framework with school and district leaders.

PubMed

Corn, Jenifer O; Byrom, Elizabeth; Knestis, Kirk; Matzen, Nita; Thrift, Beth

2012-11-01

Schools, districts, and state-level educational organizations are experiencing a great shift in the way they do the business of education. This shift focuses on accountability, specifically through the expectation of the effective utilization of evaluative-focused efforts to guide and support decisions about educational program implementation. In as much, education leaders need specific guidance and training on how to plan, implement, and use evaluation to critically examine district and school-level initiatives. One specific effort intended to address this need is through the Capacity for Applying Project Evaluation (CAPE) framework. The CAPE framework is composed of three crucial components: a collection of evaluation resources; a professional development model; and a conceptual framework that guides the work to support evaluation planning and implementation in schools and districts. School and district teams serve as active participants in the professional development and ultimately as formative evaluators of their own school or district-level programs by working collaboratively with evaluation experts. The CAPE framework involves the school and district staff in planning and implementing their evaluation. They are the ones deciding what evaluation questions to ask, which instruments to use, what data to collect, and how and to whom results should be reported. Initially this work is done through careful scaffolding by evaluation experts, where supports are slowly pulled away as the educators gain experience and confidence in their knowledge and skills as evaluators. Since CAPE engages all stakeholders in all stages of the evaluation, the philosophical intentions of these efforts to build capacity for formative evaluation strictly aligns with the collaborative evaluation approach. Copyright © 2012 Elsevier Ltd. All rights reserved.

Evaluating the Photoprotective Effects of Ochre on Human Skin by In Vivo SPF Assessment: Implications for Human Evolution, Adaptation and Dispersal.

PubMed

Rifkin, Riaan F; Dayet, Laure; Queffelec, Alain; Summers, Beverley; Lategan, Marlize; d'Errico, Francesco

2015-01-01

Archaeological indicators of cognitively modern behaviour become increasingly prevalent during the African Middle Stone Age (MSA). Although the exploitation of ochre is viewed as a key feature of the emergence of modern human behaviour, the uses to which ochre and ochre-based mixtures were put remain ambiguous. Here we present the results of an experimental study exploring the efficacy of ochre as a topical photoprotective compound. This is achieved through the in vivo calculation of the sun protection factor (SPF) values of ochre samples obtained from Ovahimba women (Kunene Region, Northern Namibia) and the Palaeozoic Bokkeveld Group deposits of the Cape Supergroup (Western Cape Province, South Africa). We employ visible spectroscopy, energy-dispersive X-ray fluorescence (ED-XRF), X-ray diffraction (XRD) and granulometric analyses to characterise ochre samples. The capacity of ochre to inhibit the susceptibility of humans to the harmful effects of exposure to ultraviolet radiation (UVR) is confirmed and the mechanisms implicated in the efficacy of ochre as a sunscreen identified. It is posited that the habitual application of ochre may have represented a crucial innovation for MSA humans by limiting the adverse effects of ultraviolet exposure. This may have facilitated the colonisation of geographic regions largely unfavourable to the constitutive skin colour of newly arriving populations.

Space station accommodations for lunar base elements: A study

NASA Technical Reports Server (NTRS)

Weidman, Deene J.; Cirillo, William; Llewellyn, Charles; Kaszubowski, Martin; Kienlen, E. Michael, Jr.

1987-01-01

The results of a study conducted at NASA-LaRC to assess the impact on the space station of accommodating a Manned Lunar Base are documented. Included in the study are assembly activities for all infrastructure components, resupply and operations support for lunar base elements, crew activity requirements, the effect of lunar activities on Cape Kennedy operations, and the effect on space station science missions. Technology needs to prepare for such missions are also defined. Results of the study indicate that the space station can support the manned lunar base missions with the addition of a Fuel Depot Facility and a heavy lift launch vehicle to support the large launch requirements.

A 'private adventure'? John Herschel's Cape voyage and the production of the 'Cape Results'

NASA Astrophysics Data System (ADS)

Ruskin, Steven William

2002-07-01

This dissertation considers the life of John Herschel (1792 1871) from the years 1833 to 1847. In 1833 Herschel sailed from London to Cape Town, southern Africa, to undertake (at his own expense) an astronomical exploration of the southern heavens, as well as a terrestrial exploration of the area around Cape Town. After his return to England in 1838, he was highly esteemed and became Britain's most recognized scientist. In 1847 his southern hemisphere astronomical observations were published as the Cape Results. The main argument of this dissertation is that Herschel's voyage, and the publication of the Cape Results, in addition to their contemporary scientific importance, were also significant for nineteenth-century politics and culture. This dissertation is a two-part dissertation. The first part is entitled “John Herschel's Cape Voyage: Private Science, Public Imagination, and the Ambitions of Empire”; and the second part, “The Production of the Cape Results.” In the first part it is demonstrated that the reason for Herschel's cultural renown was the popular notion that his voyage to the Cape was a project aligned with the imperial ambitions of the British government. By leaving England for one of its colonies, and pursuing there a significant scientific project, Herschel was seen in the same light as other British men of science who had also undertaken voyages of exploration and discovery. It is then demonstrated, in the second part of this work, that the production of the Cape Results, in part because of Herschel's status as Britain's scientific figurehead, was a significant political and cultural event. In addition to the narrow area of Herschel scholarship, this dissertation touches on other areas of research in the history of science as well: science and culture, science and empire, science and politics, and what has been called the “new” history of scientific books.

Cubesat Application for Planetary Entry (CAPE) Missions: Micro-Return Capsule (MIRCA)

NASA Technical Reports Server (NTRS)

Esper, Jaime

2016-01-01

The Cubesat Application for Planetary Entry Missions (CAPE) concept describes a high-performing Cubesat system which includes a propulsion module and miniaturized technologies capable of surviving atmospheric entry heating, while reliably transmitting scientific and engineering data. The Micro Return Capsule (MIRCA) is CAPE's first planetary entry probe flight prototype. Within this context, this paper briefly describes CAPE's configuration and typical operational scenario, and summarizes ongoing work on the design and basic aerodynamic characteristics of the prototype MIRCA vehicle. CAPE not only opens the door to new planetary mission capabilities, it also offers relatively low-cost opportunities especially suitable to university participation. In broad terms, CAPE consists of two main functional components: the "service module" (SM), and "CAPE's entry probe" (CEP). The SM contains the subsystems necessary to support vehicle targeting (propulsion, ACS, computer, power) and the communications capability to relay data from the CEP probe to an orbiting "mother-ship". The CEP itself carries the scientific instrumentation capable of measuring atmospheric properties (such as density, temperature, composition), and embedded engineering sensors for Entry, Descent, and Landing (EDL). The first flight of MIRCA was successfully completed on 10 October 2015 as a "piggy-back" payload onboard a NASA stratospheric balloon launched from Ft. Sumner, NM.

Cape Province, South Africa as seen from STS-58

NASA Image and Video Library

1993-10-30

STS058-77-083 (18 Oct-1 Nov 1993) --- In this scene of the south coast of Africa, Cape Agulhas, the southernmost point on the continent, appears as the leftmost cape. Viewed with the Earth's limb top left, clouds at bottom, the view direction is west and north top right. The Cape of Good Hope, with Cape Town nearby, is the thin spike beyond. The great bay in the foreground is Algoa Bay with the city of Port Elizabeth. This was the first time European voyagers are known to have rounded the Cape of Good Hope in their quest to reach India by sea. The entire fold mountain belt of southern Africa is visible: these mountains appear as green (forested) wavy structures stretching west form the foreground, to the Cape of Good Hope, and then northwards some distance. One theory about their origin is that the Falkland Plateau, now an undersea extension of South America, was jostled up against Africa more than 150 million years ago, in times before the Atlantic Ocean existed, before Africa and South America drifted apart from one another. The jostling caused the evolution of the fold mountain belt.

"They must understand we are people": Pregnancy and maternity service use among signing Deaf women in Cape Town.

PubMed

Gichane, Margaret W; Heap, Marion; Fontes, Mayara; London, Leslie

2017-07-01

Women with disabilities are at disproportionate risk for adverse pregnancy outcomes, however, there is limited information on their pregnancy histories. This mixed-methods study focuses on signing Deaf women whose access to health care may be compromised by language barriers related to their disability. To describe and compare the pregnancy outcomes and maternity service use of a sample of signing Deaf women of child-bearing age in Cape Town to the population of the Western Cape of South Africa. We interviewed 42 Deaf women selected by non-probability snowball sampling, using a structured questionnaire in South African Sign Language in Cape Town in July 2016. Average parity of the sample was similar to that of the Western Cape population. Most women had one or two children (74%). Thirty-one percent of women had experienced a miscarriage and 19% had terminated a pregnancy. Almost all women (96%) attended at least one antenatal appointment during their pregnancies, and all deliveries occurred at a health facility. Women primarily relied on writing to communicate during antenatal visits and labor/delivery. The majority of women reported communication issues due to limited interpretation services, and some reported experiencing mistreatment from hospital staff. This study provides novel information on the pregnancy histories of Deaf women. While maternal service usage was high, the quality of services were inadequate with reports of linguistic barriers and mistreatment. Findings suggest the need to improve maternity care for Deaf women through implementing interpretation services and providing sensitivity training to health care providers. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Patterns of genetic diversity in three plant lineages endemic to the Cape Verde Islands.

PubMed

Romeiras, Maria M; Monteiro, Filipa; Duarte, M Cristina; Schaefer, Hanno; Carine, Mark

2015-05-15

Conservation of plant diversity on islands relies on a good knowledge of the taxonomy, distribution and genetic diversity of species. In recent decades, a combination of morphology- and DNA-based approaches has become the standard for investigating island plant lineages and this has led, in some cases, to the discovery of previously overlooked diversity, including 'cryptic species'. The flora of the Cape Verde archipelago in the North Atlantic is currently thought to comprise ∼740 vascular plant species, 92 of them endemics. Despite the fact that it is considered relatively well known, there has been a 12 % increase in the number of endemics in the last two decades. Relatively few of the Cape Verde plant lineages have been included in genetic studies so far and little is known about the patterns of diversification in the archipelago. Here we present an updated list for the endemic Cape Verde flora and analyse diversity patterns for three endemic plant lineages (Cynanchum, Globularia and Umbilicus) based on one nuclear (ITS) and four plastid DNA regions. In all three lineages, we find genetic variation. In Cynanchum, we find two distinct haplotypes with no clear geographical pattern, possibly reflecting different ploidy levels. In Globularia and Umbilicus, differentiation is evident between populations from northern and southern islands. Isolation and drift resulting from the small and fragmented distributions, coupled with the significant distances separating the northern and southern islands, could explain this pattern. Overall, our study suggests that the diversity in the endemic vascular flora of Cape Verde is higher than previously thought and further work is necessary to characterize the flora. Published by Oxford University Press on behalf of the Annals of Botany Company.

Western Cape Primary Care Assessment Tool (PCAT) study: Measuring primary care organisation and performance in the Western Cape Province, South Africa (2013)

PubMed Central

Sayed, Abdul-Rauf; le Grange, Cynthia; Bhagwan, Susheela; Manga, Nayna; Hellenberg, Derek

2016-01-01

Background Major health sector reform and the need for baseline measures of performance to determine impact. Aim Baseline audit of primary healthcare (PHC) performance. Setting Cape Town and Cape Winelands (rural) PHC facilities (PCFs) in Western Cape Province, South Africa. Method The South African cross-culturally validated ZA PCAT to audit PHC performance on 11 subdomains associated with improved health and reduced costs. Adult PCF users systematically sampled. All full-time doctors and nurse practitioners in PCFs sampled and all PCF managers in sub-districts sampled invited into the study. Results Data from 1432 users, 100 clinicians and 64 managers from 13 PCFs in 10 sub-districts analysed (figures show stakeholder percentages scoring subdomain performance ‘acceptable to good’). 11.5% users scored access ‘acceptable to good’; community orientation and comprehensive services provided 20.8% and 39.9%, respectively. Total PHC score for users 50.2%; for managers and practitioners 82.8% and 88.0%, respectively. Among practitioners access was lowest (33.3%); PHC team (98.0%) and comprehensive services available (100.0%) highest. Among managers, access (13.5%) and family centredness (45.6%) are lowest; PHC team (85.9%) and comprehensive services available (90.6%) highest. Managers scored access, family centredness and cultural competence significantly lower than practitioners. Users scored comprehensive services available, comprehensive services provided and community orientation significantly lower than practitioners and managers. Conclusion Gaps between users’ experience and providers’ assessments of PHC performance are identified. Features that need strengthening and alignment with best practice, provincial and national, and health policies are highlighted with implications for practitioner and manager training, health policy, and research. PMID:27247157

Stress history and geotechnical properties of sediment from the Cape Fear Diapir, Blake Ridge Diapir, and Blake Ridge

USGS Publications Warehouse

Winters, W.J.

2000-01-01

Geotechnical properties of sediment from Ocean Drilling Program Leg 164 are presented as: (1) normalized shipboard strength ratios from the Cape Fear Diapir, the Blake Ridge Diapir, and the Blake Ridge; and (2) Atterberg limit, vane shear strength, pocket-penetrometer strength, and constant-rate-of-strain consolidation results from Hole 995A, located on the Blake Ridge. This study was conducted to understand the stress history in a region characterized by high sedimentation rates and the presence of gas hydrates. Collectively, the results indicate that sediment from the Blake Ridge exhibits significant underconsolidated behavior, except near the seafloor. At least 10 m of additional overburden was removed by erosion or mass wasting at Hole 993A on the Cape Fear Diapir, compared to nearby sites.

EPA Cape Cod 208 Plan 2015 Update Approval Letter

EPA Pesticide Factsheets

EPA approval letter re: certification by the Governor of MA that the Cape Cod WQM Plan Update is consistent with CWA section 208(b)(3) & accepted the Commonwealth’s reaffirmation of the existing designations of Cape Cod Towns as waste management agencies.

43. CAPE COD AIR STATION PAVE PAWS FACILITY WITH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

43. CAPE COD AIR STATION PAVE PAWS FACILITY - WITH BUILDING METAL SIDING BEING APPLIED ON "C" FACE (RIGHT) AND "B" FACE BEING PREPARED FOR INSTALLATION. - Cape Cod Air Station, Technical Facility-Scanner Building & Power Plant, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

DEVELOPMENT OF CAPE-OPEN COMPLIANT PROCESS MODELING COMPONENTS IN MICROSOFT .NET

EPA Science Inventory

The CAPE-OPEN middleware standards were created to allow process modeling components (PMCs) developed by third parties to be used in any process modeling environment (PME) utilizing these standards. The CAPE-OPEN middleware specifications were based upon both Microsoft's Compone...

CAPE-OPEN WITH .NET TRAINING COURSE

EPA Science Inventory

On March 7, 2007 in Heidelberg, Germany, the CAPE-OPEN Laboratories Network (CO-LaN) is offering a one-day training seminar on implementing CAPE-OPEN compliant process modeling components (PMCs) using .NET-based development tools. This seminar will be geared to component develope...

Carolinas Coastal Change Processes Project data report for nearshore observations at Cape Hatteras, North Carolina

USGS Publications Warehouse

Armstrong, Brandy N.; Warner, John C.; Voulgaris, George; List, Jeffrey H.; Thieler, Robert; Martini, Marinna A.; Montgomery, Ellyn T.; McNinch, Jesse E.; Book, Jeffrey W.; Haas, Kevin

2013-01-01

An oceanographic field study conducted in February 2010 investigated processes that control nearshore flow and sediment transport dynamics at Cape Hatteras, North Carolina. This report describes the project background, field program, instrumentation setup, and locations of the sensor deployments. The data collected, and supporting meteorological and streamflow observations, are presented as time-series plots for data visualization. Additionally, the data are available as part of this report.

"It's Not Their Job to Share Content": A Case Study of the Role of Senior Students in Adapting Teaching Materials as Open Educational Resources at the University of Cape Town

ERIC Educational Resources Information Center

Hodgkinson-Williams, Cheryl; Paskevicius, Michael

2013-01-01

Inspired by the Massachusetts Institute of Technology's landmark decision to make its teaching and learning materials freely available to the public as OpenCourseWare (OCW), many other higher education institutions have followed suit sharing resources now more generally referred to as Open Educational Resources (OER). The University of Cape Town…

The importance of social context in understanding and promoting low-income immigrant women's health.

PubMed

De Jesus, Maria

2009-02-01

Understanding the social context and realities of Cape Verdean women in the U.S. as well as other immigrant and ethnic/racial groups is important to promote their overall health and well-being more effectively. The aim of this study was to gain a contextual understanding from the perspectives of health promoters who work with marginalized women. In-depth, semi-structured interviews were conducted with nine Cape Verdean women health promoters about their perspectives and experiences of health promotion practice with immigrant women in their community. Using a Glaserian grounded theory approach to analysis, six salient themes describing women's social context emerged: community and domestic violence, loss and isolation, economic injustice, immigration-related issues and abuse, unequal gender-based power relations, and cultural taboos. These findings challenge health researchers and practitioners to understand health problems and health promotion not only at an individual level, but at multiple levels of influence including interpersonal, family, neighborhood, and structural levels.

Breeding biology of the spotted salamander Ambystoma maculatum (Shaw) in acidic temporary ponds at Cape Cod, USA

USGS Publications Warehouse

Portnoy, J.W.

1990-01-01

The relationship between water chemistry and breeding success of spotted salamanders Ambystoma maculatum (Shaw) was examined in temporary woodland ponds on outer Cape Cod, Massachusetts in 1985 and 1986. Most pond waters were dilute (3median coductivity = 57 umhos cm-1 (1 umhos cm-1 = 0?1 mSm-1)), acidic (median pH = 4?82), and highly colored (median = 140 Pt-Co units). Most acidity was due to abundant organic acids. Salamander survival to hatching was over 80% at 8 of 12 ponds monitored. Complete mortality, preceded by gross abnormalities, was observed only among embryos in the most acidic spawning pond (pH 4?3-4?5) in both years. Embryo transfers between ponds and laboratory studies indicated that reduced survival was due to the interaction of low pH with high tannin-lignin concentration. The use of amphibian embryonic survival to indicate acid rain effects is complicated by multiple habitat parameters and should only be attempted in conjunction with long-term population monitoring.

MOCHA: Multi-Study Ocean Acoustics Human Effects Analysis

DTIC Science & Technology

2013-09-30

scientists of existing BRS projects (Sirena sonar trials on sperm whales, Bahamas BRS, SOCAL BRS, Norwegian 3S and 3S2, Cape Hatteras EK60...Over the course of the project we are holding a series of workshops attended by the working group, steering group and project post-doctoral researchers...began with deep divers (beaked whales and sperm whales) because this group contains species of concern, there are data for these species across

Hydrogeologic framework of the North Carolina coastal plain

USGS Publications Warehouse

Winner, M.D.; Coble, R.W.

1996-01-01

The hydrogeologic framework of the North Carolina Coastal Plain aquifer system consists of 10 aquifers separated by 9 confining units. From top to bottom, the aquifers are the surficial aquifer, Yorktown aquifer, Pungo River aquifer, Castle Hayne aquifer, Beaufort aquifer, Peedee aquifer, Black Creek aquifer, upper Cape Fear aquifer, lower Cape Fear aquifer, and Lower Cretaceous aquifer. The uppermost aquifer (the surficial aquifer in most places) is a water-table aquifer, and the bottom of the system is underlain by crystalline bedrock. The sedimentary deposits forming the aquifers are of Holocene to Cretaceous age and are composed mostly of sand, with lesser amounts of gravel and limestone. The confining units between the aquifers are composed primarily of clay and silt. The thickness of the aquifers ranges from zero along the Fall Line to more than 10,000 feet at Cape Hatteras. Prominent structural features are the increasing easterly homoclinal dip of the sediments and the Cape Fear arch, the axis of which trends in a southeast direction. Stratigraphic continuity was determined from correlations of 161 geophysical logs along with data from drillers? and geologists? logs. Aquifers were defined by means of these logs as well as water-level and water-quality data and evidence of the continuity of pumping effects. Eighteen hydrogeologic sections depict the correlation of these aquifers throughout the North Carolina Coastal Plain.

Evaluation of the Cape Seal Process as a Pavement Rehabilitation Alternative

DOT National Transportation Integrated Search

1998-10-01

A 1-year research project was conducted to evaluate the Cape seal process as a pavement rehabilitation technique. During the course of this research project, most of the Cape seal projects that have been constructed within the state were visited as p...

42. CAPE COD AIR STATION PAVE PAWS FACILITY SHOWING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

42. CAPE COD AIR STATION PAVE PAWS FACILITY - SHOWING BUILDING "RED IRON" STEEL STRUCTURE AT 46T DAY OF STEEL CONSTRUCTION. "BUILDING TOPPED OFF, 7 JULY, 1974. - Cape Cod Air Station, Technical Facility-Scanner Building & Power Plant, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

TECHNOLOGIES FOR MONITORING AND MEASUREMENT ...

EPA Pesticide Factsheets

A demonstration of technologies for determining the presence of dioxin and dioxin-like compounds in soil and sediment was conducted under EPA's Superfund Innovative Technology Evaluation Program in Saginaw, Michigan in April 2004. This report describes the performance evaluation of CAPE Technologies DF-1 Dioxin/Furan and PCB TEQ Immunoassay Kits. The kits are immunoassay techniques that report the total toxicity equivalents (TEQ) of dioxin/furans and polychlorinated biphenyls (PCBs. The technology results were compared to high resolution mass spectrometry TEQ results generated using EPA Methods 1613B and 1668A.The CAPE Technologies kits generally reported data higher than the certified PE and reference laboratory values. The technologys estimated MDL was 12 to 33 pg/g TEQ. Results from this demonstration suggest that the CAPE Technologies kits could be an effective screening tool for determining sample results above and below 20 pg/g TEQ and even more effective as a screen for sample above and below 50 pg/g TEQ, particularly considering that both the cost ($59,234 vs. $398,029) and the time (3 weeks vs. 8 months) to analyze the 209 demonstration samples were significantly less than those of the reference laboratory. The objective of this program is to promote the acceptance and use of innovative field technologies by providing well-documented performance and cost data obtained from field demonstrations.

A genetic approach to the origin of Millepora sp. in the eastern Atlantic

NASA Astrophysics Data System (ADS)

López, C.; Clemente, S.; Almeida, C.; Brito, A.; Hernández, M.

2015-06-01

Many species have experienced recent range expansions due to human-mediated processes, such as the unintentional transport on ships or plastic waste and ocean warming, which facilitates many tropical species to tolerate living beyond their normal limit of distribution, with a potential impact on autochthonous assemblages. In September 2008, three colonies of the fire coral Millepora sp. (Cnidaria: Hydrozoa) were found on the southeastern coast of Tenerife (Canary Islands), though this species had been previously described to have a circumtropical distribution with Cape Verde Islands as its northern limit of distribution in the eastern Atlantic. The aim of this study was to determine the origin of these new colonies in the Canary Islands (11°N of its previously known northernmost limit of distribution) using variation in the cytochrome oxidase subunit I (COI) gene as a molecular marker. In order to do that, Millepora samples from Tenerife and Cape Verde Islands were collected for molecular analyses, and COI sequences from Caribbean samples listed in GenBank were also included in the analysis. Our results showed that all the specimens from Tenerife were genetically identical, suggesting that the colonization of the Canary Islands was the result of a very recent and strong founder effect. The nucleotide sequences of the samples from the Cape Verde and the Canary Islands were closer to the Caribbean than between themselves, pointing to the Caribbean population as the source population for both archipelagos, through independent founder events. The fact that Millepora sp. arrived to Cape Verde long before arriving to the Canaries (pleistocene fossils have been found in that archipelago) suggests that the habitat requirements for this species did not exist before in the Canarian archipelago. Therefore, the rising seawater temperatures recently registered in the Canary Islands could have facilitated the settlement of reef-forming corals drifting across the two basins of the Atlantic.

Outsourcing vaccine logistics to the private sector: The evidence and lessons learned from the Western Cape Province in South-Africa.

PubMed

Lydon, Patrick; Raubenheimer, Ticky; Arnot-Krüger, Michelle; Zaffran, Michel

2015-06-26

With few exceptions, immunization supply chains in developing countries continue to face chronic difficulties in providing uninterrupted availability of potent vaccines up to service delivery levels, and in the most efficient manner possible. As these countries struggle to keep pace with an ever growing number of vaccines, more and more Ministries of Health are considering options of engaging the private sector to manage vaccine storage, handling and distribution on their behalf. Despite this emerging trend, there is limited evidence on the benefits or challenges of this option to improve public supply chain performance for national immunization programmes. To bridge this knowledge gap, this study aims to shed light on the value proposition of outsourcing by documenting the specific experience of the Western Cape Province of South Africa. The methodology for this review rested on conducting two key supply chain assessments which allowed juxtaposing the performance of the government managed segments of the vaccine supply chain against those managed by the private sector. In particular, measures of effective vaccine management best practice and temperature control in the cold chain were analysed. In addition, the costs of engaging the private sector were analysed to get a better understanding of the economics underpinning outsourcing vaccine logistics. The results from this analysis confirmed some of the theoretical benefits of outsourcing to the private sector. Yet, if the experience in the Western Cape can be deemed a successful one, there are several policy and practice implications that developing countries should be mindful of when considering engaging the private sector. While outsourcing can help improve the performance of the vaccine supply chain, it has the potential to do the reverse if done incorrectly. The findings and lessons learnt from the Western Cape experience can serve as a step towards understanding the role of the private sector in immunization supply chain and logistics systems for developing countries. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Female homicidal strangulation in urban South Africa

PubMed Central

Suffla, Shahnaaz; Van Niekerk, Ashley; Arendse, Najuwa

2008-01-01

Background Female strangulation in South Africa occurs in a context of pervasive and often extreme violence perpetrated against women, and therefore represents a major public health, social and human rights concern. South African studies that provide accurate descriptions of the occurrence of strangulation incidents among female homicide victims are limited. The current study describes the extent, distribution and patterns of homicidal strangulation of women in the four largest South African metropolitan centres, Tshwane/Pretoria, Johannesburg, Cape Town and Ethekwini/Durban. Methods The study is a register-based cross sectional investigation of female homicidal strangulation, as reported in the National Injury Mortality Surveillance System for the four cities, for the period 2001 to 2005. Crude, unadjusted female strangulation rates for age and population group, and proportions of strangulation across specific circumstances of occurrence were compiled for each year and aggregated in some cases. Results This study reports that female homicidal strangulation in urban South Africa ranges from 1.71/100 000 to 0.70/100 000. Rates have generally declined in all the cities, except Cape Town. The highest rates were reported in the over 60 and the 20 to 39 year old populations, and amongst women of mixed descent. Most strangulations occurred from the early morning hours and across typical working hours in Johannesburg and Durban, and to a lesser extent in Cape Town. Occurrences across Johannesburg, Durban and Pretoria were distributed across the days of the week; an exception was Cape Town, which reported the highest rates over the weekend. Cape Town also reported distinctly high blood alcohol content levels of strangulation victims. The seasonal variation in strangulation deaths suggested a pattern of occurrence generally spanning the period from end-winter to summer. Across cities, the predominant crime scene was linked to the domestic context, suggesting that perpetration was by an intimate partner or acquaintance. Conclusion The study contributes to an emerging gendered homicide risk profile for a country with one of the highest homicide rates in the world. The results support the call for the development of evidence-based and gender-specific initiatives to especially address the forms of violence that instigate fatalities. PMID:18939973

Female homicidal strangulation in urban South Africa.

PubMed

Suffla, Shahnaaz; Van Niekerk, Ashley; Arendse, Najuwa

2008-10-21

Female strangulation in South Africa occurs in a context of pervasive and often extreme violence perpetrated against women, and therefore represents a major public health, social and human rights concern. South African studies that provide accurate descriptions of the occurrence of strangulation incidents among female homicide victims are limited. The current study describes the extent, distribution and patterns of homicidal strangulation of women in the four largest South African metropolitan centres, Tshwane/Pretoria, Johannesburg, Cape Town and Ethekwini/Durban. The study is a register-based cross sectional investigation of female homicidal strangulation, as reported in the National Injury Mortality Surveillance System for the four cities, for the period 2001 to 2005. Crude, unadjusted female strangulation rates for age and population group, and proportions of strangulation across specific circumstances of occurrence were compiled for each year and aggregated in some cases. This study reports that female homicidal strangulation in urban South Africa ranges from 1.71/100 000 to 0.70/100 000. Rates have generally declined in all the cities, except Cape Town. The highest rates were reported in the over 60 and the 20 to 39 year old populations, and amongst women of mixed descent. Most strangulations occurred from the early morning hours and across typical working hours in Johannesburg and Durban, and to a lesser extent in Cape Town. Occurrences across Johannesburg, Durban and Pretoria were distributed across the days of the week; an exception was Cape Town, which reported the highest rates over the weekend. Cape Town also reported distinctly high blood alcohol content levels of strangulation victims. The seasonal variation in strangulation deaths suggested a pattern of occurrence generally spanning the period from end-winter to summer. Across cities, the predominant crime scene was linked to the domestic context, suggesting that perpetration was by an intimate partner or acquaintance. The study contributes to an emerging gendered homicide risk profile for a country with one of the highest homicide rates in the world. The results support the call for the development of evidence-based and gender-specific initiatives to especially address the forms of violence that instigate fatalities.

Increasing potential for intense tropical and subtropical thunderstorms under global warming.

PubMed

Singh, Martin S; Kuang, Zhiming; Maloney, Eric D; Hannah, Walter M; Wolding, Brandon O

2017-10-31

Intense thunderstorms produce rapid cloud updrafts and may be associated with a range of destructive weather events. An important ingredient in measures of the potential for intense thunderstorms is the convective available potential energy (CAPE). Climate models project increases in summertime mean CAPE in the tropics and subtropics in response to global warming, but the physical mechanisms responsible for such increases and the implications for future thunderstorm activity remain uncertain. Here, we show that high percentiles of the CAPE distribution (CAPE extremes) also increase robustly with warming across the tropics and subtropics in an ensemble of state-of-the-art climate models, implying strong increases in the frequency of occurrence of environments conducive to intense thunderstorms in future climate projections. The increase in CAPE extremes is consistent with a recently proposed theoretical model in which CAPE depends on the influence of convective entrainment on the tropospheric lapse rate, and we demonstrate the importance of this influence for simulated CAPE extremes using a climate model in which the convective entrainment rate is varied. We further show that the theoretical model is able to account for the climatological relationship between CAPE and a measure of lower-tropospheric humidity in simulations and in observations. Our results provide a physical basis on which to understand projected future increases in intense thunderstorm potential, and they suggest that an important mechanism that contributes to such increases may be present in Earth's atmosphere. Published under the PNAS license.

Increasing potential for intense tropical and subtropical thunderstorms under global warming

PubMed Central

Kuang, Zhiming; Maloney, Eric D.; Hannah, Walter M.; Wolding, Brandon O.

2017-01-01

Intense thunderstorms produce rapid cloud updrafts and may be associated with a range of destructive weather events. An important ingredient in measures of the potential for intense thunderstorms is the convective available potential energy (CAPE). Climate models project increases in summertime mean CAPE in the tropics and subtropics in response to global warming, but the physical mechanisms responsible for such increases and the implications for future thunderstorm activity remain uncertain. Here, we show that high percentiles of the CAPE distribution (CAPE extremes) also increase robustly with warming across the tropics and subtropics in an ensemble of state-of-the-art climate models, implying strong increases in the frequency of occurrence of environments conducive to intense thunderstorms in future climate projections. The increase in CAPE extremes is consistent with a recently proposed theoretical model in which CAPE depends on the influence of convective entrainment on the tropospheric lapse rate, and we demonstrate the importance of this influence for simulated CAPE extremes using a climate model in which the convective entrainment rate is varied. We further show that the theoretical model is able to account for the climatological relationship between CAPE and a measure of lower-tropospheric humidity in simulations and in observations. Our results provide a physical basis on which to understand projected future increases in intense thunderstorm potential, and they suggest that an important mechanism that contributes to such increases may be present in Earth’s atmosphere. PMID:29078312

Determination of flow losses in the Cape Fear River between B. Everett Jordan Lake and Lillington, North Carolina, 2008-2010

USGS Publications Warehouse

Weaver, J. Curtis; McSwain, Kristen Bukowski

2013-01-01

During 2008-2010, the U.S. Geological Survey conducted a hydrologic investigation in cooperation with the Triangle J Council of Governments Cape Fear River Flow Study Committee and the North Carolina Division of Water Resources to collect hydrologic data in the Cape Fear River between B. Everett Jordan Lake and Lillington in central North Carolina to help determine if suspected flow losses occur in the reach. Flow loss analyses were completed by summing the daily flow releases at Jordan Lake Dam with the daily discharges at Deep River at Moncure and Buckhorn Creek near Corinth, then subtracting these values from the daily discharges at Cape Fear River at Lillington. Examination of long-term records revealed that during 10,227 days of the 1983-2010 water years, 408 days (4.0 percent) had flow loss when conditions were relatively steady with respect to the previous day's records. The flow loss that occurred on these 40 days ranged from 0.49 to 2,150 cubic feet per second with a median flow loss of 37.2 cubic feet per second. The months with the highest number of days with flow losses were June (16. percent), September (16.9 percent), and October (19.4 percent). A series of synoptic discharge measurements made on six separate days in 2009 provided "snapshots" of overall flow conditions along the study reach. The largest water diversion is just downstream from the confluence of the Haw and Deep Rivers, and discharges substantially decrease in the main stem downstream from the intake point. Downstream from Buckhorn Dam, minimal gain or loss between the dam and Raven Rock State Park was noted. Analyses of discharge measurements and ratings for two streamgages-one at Deep River at Moncure and the other at Cape Fear River at Lillington-were completed to address the accuracy of the relation between stage and discharge at these sites. The ratings analyses did not indicate a particular time during the 1982-2011 water years in which a consistent bias occurred in the computations of discharge records that would indicate false flow losses. A total of 34 measured discharges at a streamgage on the Haw River below B. Everett Jordan Lake near Moncure were compared with the reported hourly flow releases from Jordan Lake Dam. Because 28 of 34 measurements were within plus or minus 10 percent of the hourly flow releases reported by the U.S Army Corps of Engineers, use of the current discharge computation tables for reporting Jordan Lake Dam flow releases is generally supported. A stage gage was operated on the Cape Fear River at Buckhorn Dam near Corinth to collect continuous stage-only records. Throughout the study period, flow over the dam was observed along its length, and flow loss within the study reach is not attributed to river-level fluctuations at the dam. Water-use information and (or) data were obtained for five industrial facilities, a regional power utility, two municipalities, one small hydropower facility on the Deep River, and one quarry operation also adjacent to the Deep River. The largest water users are the regional power producer, a small hydropower operation, and the two municipalities. The total water-use diversions for these facilities range from almost 25.5 to 38.5 cubic feet per second (39.5 to 59.5 million gallons per day) during the winter and summer periods, respectively. This range is equivalent to 69 to 104 percent of the 37 cubic feet per second median flow loss. The Lockville hydropower station is on the Deep River about 1 mile downstream from the streamgage near Moncure. Run-of-river operations at the facility do not appear to affect flow losses in the study reach. The largest water user in the study area is a regional power producer at a coal-fired power-generation plant located immediately adjacent to the Cape Fear River just downstream from the confluence of the Haw an Deep Rivers. Comparisons of daily water withdrawals, sup-plied by the regional power producer, and discharge records at a streamgage on the diversion canal indicated many days when consumption exceeded the producer's estimates for the cooling towers. Uncertainty surrounding reasonable estimates of consumption remained in effect at the end of the study. Data concerning evaporative losses were compiled using two approaches-an analysis of available pan-evaporation data from a National Weather Service cooperative observer station in Chapel Hill, North Carolina; and a compilation of reference open-water evaporation computed by the State Climate Office of North Carolina. The potential flow loss by evaporation from the main stem and the Deep River was estimated to be in the range of 4 to 14 cubic feet per second during May through October, equivalent to 10 to 38 percent of the 37 cubic feet per second median flow loss. Daily water-use diversions and evaporation losses were compared to flow-loss occurrences during the period April 2008 through September 2010. In comparing the surface-water, water-use, and evaporation data compiled for 2008-2010, it is evident that documented water diversions combined with flow losses by open-water evaporation can exceed the net flow gain in the study area and result in flow losses from the reach. Analysis of data from a streamgage downstream from the regional power plant on the diversion canal adjacent to the Cape Fear River provided insight into the occurrence of an apparent flow loss at the streamgage at Lillington. Assessment of the daily discharges and subsequent hydrographs for the canal streamgage indicated at least 24 instances during the study when the flows suddenly changed by magnitudes of 100 to more that 200 cubic feet per second, resulting in a noted time-lag effect on the downstream discharges at the Lillington streamgage, beginning 8 to 16 hours after the sudden flow change. A fiber-optic distributed temperature-sensing survey was conducted on the Cape Fear River at the Raven Rock State Park reach August 12-14, 2009, to determine if the presence of diabase dikes were preferentially directing groundwater discharge. No temperature anomalies of colder water were measured during the survey, which indicated that at the time of the survey that particular reach of the Cape Fear River was a "no-flow" or losing stream. An aerial thermal-infrared survey was conducted on the Haw and Cape Fear Rivers on February 27, 2010, from Jordan Lake Dam to Lillington to qualitatively delineate areas of groundwater discharge on the basis of the contrast between warm groundwater discharge and cold surface-water temperatures. Dis-charge generally was noted as diffuse seepage, but in a few cases springs were detected as inflow at a discrete point of discharge. Two reaches of the Cape Fear River (regional power plant and Bradley Road reaches) were selected for groundwater monitoring with a transect of piezometers installed within the flood plain. Groundwater-level altitudes at these reaches were analyzed for 1 water year (October 1, 2009, to September 30, 2010). Data collected as part of this study represent only a brief period of time and may not represent all conditions and all years; however, the data indicate that, during the dry summer months, the Cape Fear River within the study area is losing an undetermined quantity of water through seepage. Analyses completed during this investigation indicate a study reach with complex flow patterns affected by numerous concurrent factors resulting in flow losses. The causes of flow loss could not be solely attributed to any one factor. Among the factors considered, the occurrences of water diversions and evaporative losses were determined to be sufficient on some days (particularly during the base-flow period) to exceed the net gain in flows between the upstream and downstream ends of the study area. Losses by diversions and evaporation can exceed the median flow loss of 3 cubic feet per second, which indicates that flow loss from the study reach is real. Groundwater data collected during 2009-2010 indicate the possibility of localized flow loss during the summer, particularly in the impounded reach above Buckhorn Dam. However, no indication of unusual patterns was noted that would cause substantial flow loss by groundwater and surface-water interaction at the river bottom.

KSC-01PP1052

NASA Image and Video Library

2001-05-31

The first stage of the Geostationary Operational Environmental Satellite-M (GOES-M) Atlas II rocket arrives at Complex 36-A, Cape Canaveral Air Force Station. It will be raised and lifted up the gantry for mating with other stages. The last in the current series of advanced geostationary weather satellites in service, GOES-M has a new instrument not on earlier spacecraft, a Solar X-ray Imager that can be used in forecasting space weather, the effects of solar storms that create electromagnetic disturbances on earth that affect other satellites, communications and power grids. GOES-M is scheduled to launch from Launch Complex 36-A, Cape Canaveral Air Force Station July 15

KSC-01pp1065

NASA Image and Video Library

2001-06-02

KENNEDY SPACE CENTER, Fla. -- At Complex 36-A, Cape Canaveral Air Force Station, the second stage of the Geostationary Operational Environmental Satellite-M (GOES-M) Atlas II rocket is lifted up the gantry for mating with the first stage. The last in the current series of advanced geostationary weather satellites in service, GOES-M has a new instrument not on earlier spacecraft, a Solar X-ray Imager that can be used in forecasting space weather, the effects of solar storms that create electromagnetic disturbances on earth that affect other satellites, communications and power grids. GOES-M is scheduled to launch from Cape Canaveral Air Force Station July 15

KSC-01pp1066

NASA Image and Video Library

2001-06-02

KENNEDY SPACE CENTER, Fla. -- At Complex 36-A, Cape Canaveral Air Force Station, the second stage of the Geostationary Operational Environmental Satellite-M (GOES-M) Atlas II rocket nears the top of the gantry. It will be mated with the first stage. The last in the current series of advanced geostationary weather satellites in service, GOES-M has a new instrument not on earlier spacecraft, a Solar X-ray Imager that can be used in forecasting space weather, the effects of solar storms that create electromagnetic disturbances on earth that affect other satellites, communications and power grids. GOES-M is scheduled to launch from Cape Canaveral Air Force Station July 15

KSC-69PC-0397

NASA Image and Video Library

1969-07-16

CAPE CANAVERAL, Fla. -- The American Flag heralds the flight of Apollo 11, man's first lunar landing mission. This double exposure was made with a 1,000 mm lens. The photograph was taken from Cape Kennedy, adjacent to Kennedy Space Center, where Apollo 11 lifted off from pad 39A at 9:32 a.m. EDT. This image was imposed upon the image of hte flag, filmed a day earlier. In the photo, the rocket at an alititude of about 5,000 feet. A band of super-cold propellants seems to circle the rocket near its center. The effect is caused by the difference in temperature between the propellants and the atmosphere. Photo credit: NASA

Outlook. Number 367

ERIC Educational Resources Information Center

Council for American Private Education, 2011

2011-01-01

Council for American Private Education (CAPE) is a coalition of national associations serving private schools K-12. "Outlook" is published monthly by CAPE. This issue contains the following articles: (1) Historic Year for School Choice; (2) Above-Average Scores in Geography and U.S. History; (3) Early Learning; and (4) CAPE Notes.

76 FR 2705 - Notice of Continuation of Visitor Services

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-14

... Sports & Shenandoah National Park. Entertainment Services, Inc. DEVA002-81 Xanterra Parks & Death Valley... ARAMARK Sports & Olympic National Park. Entertainment, Inc. OLYM002-89 Log Cabin Resort, Inc. Olympic... Cape Hatteras Fishing Cape Hatteras National Seashore. Pier, Inc. CAHA004-98 Oregon Inlet Fishing Cape...

Outlook. Number 372

ERIC Educational Resources Information Center

Council for American Private Education, 2012

2012-01-01

Council for American Private Education (CAPE) is a coalition of national associations serving private schools K-12. "Outlook" is published monthly by CAPE. This issue contains the following articles: (1) Supreme Court Issues 9-0 Ruling in Religious School Case; (2) White House Honors Champions of Change; and (3) CAPE Notes.

Empowering Lay-Counsellors with Technology: Masivukeni, a Standardized Multimedia Counselling Support Tool to Deliver ART Counselling.

PubMed

Gouse, H; Robbins, R N; Mellins, C A; Kingon, A; Rowe, J; Henry, M; Remien, R H; Pearson, A; Victor, F; Joska, J A

2018-05-19

Lay-counsellors in resource-limited settings convey critical HIV- and ART-information, and face challenges including limited training and variable application of counselling. This study explored lay-counsellors and Department of Health (DoH) perspectives on the utility of a multimedia adherence counselling program. Masivukeni, an mHealth application that provides scaffolding for delivering standardized ART counselling was used in a 3-year randomized control trail at two primary health care clinics in Cape Town, South Africa. In this programmatic and descriptive narrative report, we describe the application; lay-counsellors' response to open-ended questions regarding their experience with using Masivukeni; and perspectives of the City of Cape Town and Western Cape Government DoH, obtained through ongoing engagements and feedback sessions. Counsellors reported Masivukeni empowered them to provide high quality counselling. DoH indicated strong support for a future implementation study assessing feasibility for larger scale roll-out. Masivukeni has potential as a counselling tool in resource-limited settings.

Characterization of convection-related parameters by Raman lidar: Selected case studies from the convective and orographically-induced precipitation study

NASA Astrophysics Data System (ADS)

Di Girolamo, Paolo; Summa, Donato; Stelitano, Dario

2013-05-01

An approach to determine the convective available potential energy (CAPE) and the convective inhibition (CIN) based on the use of data from a Raman lidar system is illustrated in this work. The use of Raman lidar data allows to provide high temporal resolution measurements (5 min) of CAPE and CIN and follow their evolution over extended time periods covering the full cycle of convective activity. Lidar-based measurements of CAPE and CIN are obtained from Raman lidar measurements of the temperature and water vapor mixing ratio profiles and the surface measurements of temperature, pressure and dew point temperature provided by a surface weather station. The approach is applied to the data collected by the Raman lidar system BASIL in the frame of COPS. Attention was focused on 15 July and 25-26 July 2007. Lidar-based measurements are in good agreement with simultaneous measurements from radiosondes and with estimates from different mesoscale models.

The Philani Mentor Mothers Intervention: Neighbourhood wide impact on child growth in Cape Town's peri-urban settlements.

PubMed

Tomlinson, Mark; Hartley, Mary; le Roux, Ingrid; Rotheram-Borus, Mary Jane

2016-01-01

The purpose of this research was to determine whether or not routine home visiting (by the Philani Maternal Child Health and Nutrition Project) influences the prevalence of stunted, wasted and underweight children in Cape Town peri-urban settlements. The study was a cross-sectional cohort in which weight and height measurements were collected for all children from 24 matched neighbourhoods; three years earlier 12 of these neighbourhoods were randomized to receive the home visiting intervention and 12 did not. The research took place at all households located within the 24 neighbourhoods in Khayelitsha and Mfuleni peri-urban settlements. Participants included 8715 children aged 0-6 years old (4694 intervention; 4021 control). A total of 41.3% of children were stunted, 3.1% were underweight and 1.4% were wasted. Children in the intervention group were significantly less likely to be underweight or severely underweight for age than children in the control group. While the rates of stunting were also significantly lower in intervention areas, the effect was not clinically significant, and no significant differences were found between the study arms on the prevalence of wasting. The Philani model is effective in the prevention and rehabilitation of underweight children. Philani could strengthen their intervention by focussing specifically on screening for child stunting in addition to underweight children. The results also suggests that efforts to address the long-term adverse effects of undernutrition require structural and economic transformation, in addition to socio-medical intervention.

Healthcare provider views on the health effects of biomass fuel collection and use in rural Eastern Cape, South Africa: an ethnographic study.

PubMed

Matinga, Margaret Njirambo; Annegarn, Harold J; Clancy, Joy S

2013-11-01

Policymakers at global level recognise that household biomass use in developing countries has significant health consequences. However, it is unclear how local-level health professionals perceive and respond to such health effects. This paper which is derived from the findings of a larger study on perceptions and responses to the harmful health effects of carrying heavy firewood loads and to smoke from cooking fires is based on a study conducted in South Africa among managers of health programmes and community nurses of Qaukeni and Mhlontlo municipalities in rural Eastern Cape. Interviews and participant observations were conducted in 2009 using ethnographic grounded theory approaches. In addition to a 10-month period of ethnographic fieldwork, ten programme managers and nurses in two villages were interviewed about health patterns in the villages that they serve, their perceptions of, and responses to the health effects of carrying heavy firewood loads, and inhalation of smoke from wood and dung cooking fires, their professional qualifications and experience, their own household energy use; and observations made as they served clinic clients. Results show that these programme managers and nurses perceive the health effects of carrying heavy loads of firewood and of cooking smoke as minor. Sometimes, nurses give women symptomatic relief for musculoskeletal pain resulting from carrying heavy loads. We posit that their perceptions are derived from customary neglect of work-related health and non-communicable diseases, cultural interpretations of womanhood, limited access to relevant information, and limited interactions between health and energy sector professionals. We conclude that culturally and gender-sensitive awareness programmes are needed for local-level health professionals to effectively address health effects of biomass collection and use. This paper provides new insights into overlooked differences between globally-driven initiatives to address health effects of biomass use and local perceptions. Copyright © 2013 Elsevier Ltd. All rights reserved.

Knowledge of High School Learners Regarding Substance Use within High School Premises in the Buffalo Flats of East London, Eastern Cape Province, South Africa

ERIC Educational Resources Information Center

Manu, Emmanuel; Maluleke, Xavela T.; Douglas, Mbuyiselo

2017-01-01

South Africa has a high rate of substance abuse among youths both in and out of school with East London in the Eastern Cape Province experiencing an increase in young people ages 20 years and below seeking treatment for substance abuse. The purpose of the study was to explore the knowledge of high school learners (grades 10 to 12) regarding…

The United States' Next Generation of Atmospheric Composition and Coastal Ecosystem Measurements: NASA's Geostationary Coastal and Air Pollution Events (GEO-CAPE) Mission

NASA Technical Reports Server (NTRS)

Fishman, J.; Iraci, Laura T.; Al-Saddi, J.; Chance, K.; Chavez, F.; Chin, M.; Coble, P.; Davis, C.; DiGiacomo, P. M.; Edwards, D.;

Molecular Systematics of the Cape Parrot (Poicephalus robustus): Implications for Taxonomy and Conservation

PubMed Central

Coetzer, Willem G.; Downs, Colleen T.; Perrin, Mike R.; Willows-Munro, Sandi

2015-01-01

The taxonomic position of the Cape Parrot (Poicephalus robustus robustus) has been the focus of much debate. A number of authors suggest that the Cape Parrot should be viewed as a distinct species separate from the other two P. robustus subspecies (P. r. fuscicollis and P. r. suahelicus). These recommendations were based on morphological, ecological, and behavioural assessments. In this study we investigated the validity of these recommendations using multilocus DNA analyses. We genotyped 138 specimens from five Poicephalus species (P. cryptoxanthus, P. gulielmi, P. meyeri, P. robustus, and P. rueppellii) using 11 microsatellite loci. Additionally, two mitochondrial (cytochrome oxidase I gene and 16S ribosomal RNA) and one nuclear intron (intron 7 of the β-fibrinogen gene) markers were amplified and sequenced. Bayesian clustering analysis and pairwise FST analysis of microsatellite data identified P. r. robustus as genetically distinct from the other P. robustus subspecies. Phylogenetic and molecular clock analyses on sequence data also supported the microsatellite analyses, placing P. r. robustus in a distinct clade separate from the other P. robustus subspecies. Molecular clock analysis places the most recent common ancestor between P. r. robustus and P. r. fuscicollis / P. r. suahelicus at 2.13 to 2.67 million years ago. Our results all support previous recommendations to elevate the Cape Parrot to species level. This will facilitate better planning and implementation of international and local conservation management strategies for the Cape Parrot. PMID:26267261

Common mutation causes cystinosis in the majority of black South African patients.

PubMed

Owen, E Patricia; Nandhlal, Jenisha; Leisegang, Felicity; Van der Watt, George; Nourse, Peter; Gajjar, Priya

2015-04-01

The mutations responsible for cystinosis in South African patients are currently unknown. A pertinent question is whether they are similar to those described elsewhere in the world. Children who were being managed for cystinosis in the Western Cape Province of South Africa between 2002 and 2013 were studied. All underwent molecular analysis to detect sequence variations in the cystinosis gene. This cohort study included 20 patients, 13 of whom were Xhosa-speaking black South Africans and seven were Cape Coloureds (mixed race); none were Caucasian. All had nephropathic infantile-type cystinosis with evidence of proximal tubulopathy, with glycosuria and renal phosphate wasting. Diagnosis was confirmed in 19 cases by demonstrating an elevated cystine concentration in leukocytes. Molecular analysis of the cystinosin gene revealed that 19 patients had a G > A mutation in intron 11 (CTNS-c.971-12G > A p.D324AfsX44) which caused an out-of-frame 10-bp insertion. Of these 19 patients, 16 were homozygous for this mutation, which was the most frequent mutation identified in the alleles of the black South African and Cape Coloured patients (96 and 71 %, respectively). We recommend that black South African and Cape Coloured patients presenting with cystinosis be tested for CTNS-c.971-12G > A in the first instance, with the possibility of prenatal testing being offered to at-risk families.

Veterinary diclofenac threatens Africa's endangered vulture species.

PubMed

Naidoo, V; Wolter, K; Cuthbert, R; Duncan, N

2009-04-01

Veterinary diclofenac has been responsible for the devastation of three species of Gyps vulture on the Indian subcontinent, and it is now regarded as one of the worst environmental contaminants in the recent past. While measures have been taken to control the manufacture of veterinary diclofenac in South Asia, the promotion of diclofenac on the African continent poses a risk to vultures in this region. In Southern Africa, the species of greatest conservation concern is the Cape Griffon Vulture (Gyps coprotheres), as only 2900 breeding pairs remain in the wild. The objective of this study was to test if this species is toxicologically sensitive to diclofenac. In a single dose-toxicity study, two adult Cape Griffon Vultures with severe injuries, that were considered to have a very poor prognostic outcome, were dosed intravenously with diclofenac at 0.8mg/kg. The changes in the clinical pathology were compared to the normal reference range established for 24 healthy Cape Griffon Vultures. Both birds died within 48h of dosing. The clinical signs, clinical pathology, gross pathology and histopathological finding were typical for diclofenac toxicity. It would appear that the sensitivity of the Cape Griffon is similar to that of their Asian counterparts and the African White-backed Vulture (Gyps africanus). Diclofenac is almost certainly toxic to all Gyps vultures species and strong efforts must be taken to ensure that veterinary diclofenac products are not licensed or introduced to the African continent.

First biological control agent released against Cape-ivy

USDA-ARS?s Scientific Manuscript database

Cape-ivy (Delairea odorata, Asteraceae) is one of the worst invasive weeds in California, colonizing riparian, forest, and scrub habitats along the California coast and East Bay hills. Cape-ivy can smother native oaks and other trees, displace native herbs and shrubs, and clog water flow along fresh...

41. Photographic copy of the original construction drawing, 192627, by ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

41. Photographic copy of the original construction drawing, 1926-27, by Harrington, Howard, and Ash, Consulting Engineers, from microfilm copy at Bridge Division, Missouri Highway and Transportation Department, Jefferson City, Missouri. STRESS SHEET - Cape Girardeau Bridge, Spanning Mississippi River at State Highway 146, Cape Girardeau, Cape Girardeau County, MO

17. CAPE COD AIR STATION PAVE PAWS FACILITY AERIAL VIEW ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. CAPE COD AIR STATION PAVE PAWS FACILITY AERIAL VIEW WITH PROJECT NEARING COMPLETION. VIEW SHOWS "A" FACE (LEFT) AND "B" FACE OF RADAR ARRAY SYSTEM. NOTE THAT NORTH IS GENERALLY TO RIGHT OF VIEW. - Cape Cod Air Station, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

47. CAPE COD AIR STATION PAVE PAWS FACILITY AERIAL VIEW ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

47. CAPE COD AIR STATION PAVE PAWS FACILITY AERIAL VIEW OF "A" FACE (LEFT) WITH CLEANING SYSTEM INSTALLED (NOW REMOVED) AND "B" FACE (RIGHT) WITH CONSTRUCTION CRANE IN USE. - Cape Cod Air Station, Technical Facility-Scanner Building & Power Plant, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

Decapoda from Antipatharia, Gorgonaria and Bivalvia at the Cape Verde Islands

NASA Astrophysics Data System (ADS)

Wirtz, Peter; d'Udekem-d'Acoz, Cédric

2001-07-01

The shrimps Balssia gasti, Palaemonella atlantica, Periclimenes platalea, Periclimenes wirtzi, Pontonia manningi, Pontonia pinnophylax, Pontonia sp. nov., Pseudocoutierea wirtzi and the crabs Galathea intermedia and Micropisa ovata were collected from Antipatharia, Gorgonaria and Bivalvia at São Tiago Island, Republic of Cape Verde. Most of the associations between decapods and invertebrate hosts are reported here for the first time. This is also the first record of B. gasti and of P. wirtzi for the Cape Verde Islands. We briefly review the literature on littoral decapod crustaceans of the Cape Verde Islands.

Quantitative Determination of Fluorinated Caffeic Acid Phenethyl Ester Derivative From Rat Blood Plasma by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry

DTIC Science & Technology

2008-03-06

Caffeic acid phenethyl ester (CAPE), a plant-derived polyphenolic compound (Fig. 1), is a component of bee propolis . Propolis has been used as a folk...analytical methods have been documented. These include an HPLC-UV determination of CAPE from a propolis -containing gel [13], HPLC-ESI-MS measurement...of CAPE from crude propolis [14], and HPLC- ESI-MS/MS analysis of CAPE in biological samples [15]. In this paper, we developed a method using ultra

The horizontal and vertical semi-diameters of the Sun observed at the Cape of Good Hope (1834 - 1887) and Paris (1837 - 1906): A report on work in progress

NASA Technical Reports Server (NTRS)

Smith, C.; Messina, D.

1981-01-01

Cape and Paris meridian observations of the solar limbs which permit an estimate to be made of the solar semi-diameter were surveyed, sampled, and compared with Greenwich and U.S. Naval Observatory observations. Significant systematic errors were found in the Paris work and have been correlated with changes of instruments and observers. Results from the Cape series indicate that work should continue on the compilation of data from Cape observations of the Sun.

Observation of Dust Aging Processes During Transport from Africa into the Caribbean - A Lagrangian Case Study

NASA Astrophysics Data System (ADS)

Weinzierl, B.; Sauer, D. N.; Walser, A.; Dollner, M.; Reitebuch, O.; Gross, S.; Chouza, F.; Ansmann, A.; Toledano, C.; Freudenthaler, V.; Kandler, K.; Schäfler, A.; Baumann, R.; Tegen, I.; Heinold, B.

2014-12-01

Aerosol particles are regularly transported over long distances impacting air quality, health, weather and climate thousands of kilometers downwind of the source. During transport, particle properties are modified thereby changing the associated impact on the radiation budget. Although mineral dust is of key importance for the climate system many questions such as the change of the dust size distribution during long-range transport, the role of wet and dry removal mechanisms, and the complex interaction between mineral dust and clouds remain open. In June/July 2013, the Saharan Aerosol Long-range Transport and Aerosol-Cloud-Interaction Experiment (SALTRACE: http://www.pa.op.dlr.de/saltrace) was conducted to study the transport and transformation of Saharan mineral dust. Besides ground-based lidar and in-situ instruments deployed on Cape Verde, Barbados and Puerto Rico, the DLR research aircraft Falcon was equipped with an extended aerosol in-situ instrumentation, a nadir-looking 2-μm wind lidar and instruments for standard meteorological parameters. During SALTRACE, five large dust outbreaks were studied by ground-based, airborne and satellite measurements between Senegal, Cape Verde, the Caribbean, and Florida. Highlights included the Lagrangian sampling of a dust plume in the Cape Verde area on 17 June which was again measured with the same instrumentation on 21 and 22 June 2013 near Barbados. Between Cape Verde and Barbados, the aerosol optical thickness (500 nm) decreased from 0.54 to 0.26 and the stratification of the dust layers changed significantly from a rather homogenous structure near Africa to a 3-layer structure with embedded cumulus clouds in the Caribbean. In the upper part of the dust layers in the Caribbean, the aerosol properties were similar to the observations near Africa. In contrast, much more variability in the dust properties was observed between 0.7 and 2.5 km altitude probably due to interaction of the mineral dust with clouds. In our presentation, we show vertical profiles of dust size distributions, CCN and dust optical properties. Based on the Lagrangian measurements, we discuss the effects of dust aging processes during long-range transport. Special attention will be given on changes in fine and coarse mode size distribution and aerosol mixing state.

Exploration of Deaf People’s Health Information Sources and Techniques for Information Delivery in Cape Town: A Qualitative Study for the Design and Development of a Mobile Health App

PubMed Central

Glaser, Meryl; Tucker, William David; Diehl, Jan Carel

2016-01-01

Background Many cultural and linguistic Deaf people in South Africa face disparity when accessing health information because of social and language barriers. The number of certified South African Sign Language interpreters (SASLIs) is also insufficient to meet the demand of the Deaf population in the country. Our research team, in collaboration with the Deaf communities in Cape Town, devised a mobile health app called SignSupport to bridge the communication gaps in health care contexts. We consequently plan to extend our work with a Health Knowledge Transfer System (HKTS) to provide Deaf people with accessible, understandable, and accurate health information. We conducted an explorative study to prepare the groundwork for the design and development of the system. Objectives To investigate the current modes of health information distributed to Deaf people in Cape Town, identify the health information sources Deaf people prefer and their reasons, and define effective techniques for delivering understandable information to generate the groundwork for the mobile health app development with and for Deaf people. Methods A qualitative methodology using semistructured interviews with sensitizing tools was used in a community-based codesign setting. A total of 23 Deaf people and 10 health professionals participated in this study. Inductive and deductive coding was used for the analysis. Results Deaf people currently have access to 4 modes of health information distribution through: Deaf and other relevant organizations, hearing health professionals, personal interactions, and the mass media. Their preferred and accessible sources are those delivering information in signed language and with communication techniques that match Deaf people’s communication needs. Accessible and accurate health information can be delivered to Deaf people by 3 effective techniques: using signed language including its dialects, through health drama with its combined techniques, and accompanying the information with pictures in combination with simple text descriptions. Conclusions We can apply the knowledge gained from this exploration to build the groundwork of the mobile health information system. We see an opportunity to design an HKTS to assist the information delivery during the patient-health professional interactions in primary health care settings. Deaf people want to understand the information relevant to their diagnosed disease and its self-management. The 3 identified effective techniques will be applied to deliver health information through the mobile health app. PMID:27836819

Health outcomes for children born to teen mothers in Cape Town, South Africa1

PubMed Central

Ardington, Cally; Leibbrandt, Murray

2014-01-01

This paper analyzes whether children born to teen mothers in Cape Town, South Africa are disadvantaged in terms of their health outcomes because their mother is a teen. Exploiting the longitudinal nature of the Cape Area Panel Study, we assess whether observable differences between teen mothers and slightly older mothers can explain why first-born children of teen mothers appear disadvantaged. Our balanced regressions indicate that observed characteristics cannot explain the full extent of disadvantage of being born to a teen mother, with children born to teen mothers continuing to have significantly worse child health outcomes, especially among coloured children. In particular, children born to teens are more likely to be underweight at birth and to be stunted with the disadvantage for coloured children four times the size for African children. PMID:26052156

Lateral conduction effects on heat-transfer data obtained with the phase-change paint technique

NASA Technical Reports Server (NTRS)

Maise, G.; Rossi, M. J.

1974-01-01

A computerized tool, CAPE, (Conduction Analysis Program using Eigenvalues) has been developed to account for lateral heat conduction in wind tunnel models in the data reduction of the phase-change paint technique. The tool also accounts for the effects of finite thickness (thin wings) and surface curvature. A special reduction procedure using just one time of melt is also possible on leading edges. A novel iterative numerical scheme was used, with discretized spatial coordinates but analytic integration in time, to solve the inverse conduction problem involved in the data reduction. A yes-no chart is provided which tells the test engineer when various corrections are large enough so that CAPE should be used. The accuracy of the phase-change paint technique in the presence of finite thickness and lateral conduction is also investigated.

Boundary layer aerosol size distribution, mass concentration and mineralogical composition in Morocco and at Cape Verde Islands during SAMUM I-II

NASA Astrophysics Data System (ADS)

Kandler, K.; Lieke, K.

2009-04-01

The Saharan Mineral Dust Experiment (SAMUM) is dedicated to the understanding of the radiative effects of mineral dust. Two major field experiments were performed: A first joint field campaign took place at Ouarzazate and near Zagora, southern Morocco, from May 13 to June 7, 2006. Aircraft and ground based measurements of aerosol physical and chemical properties were carried out to collect a data set of surface and atmospheric columnar information within a major dust source. This data set combined with satellite data provides the base of the first thorough columnar radiative closure tests in Saharan dust. A second field experiment was conducted during January-February 2008, in the Cape Verde Islands region, where about 300 Tg of mineral dust are transported annually from Western Africa across the Atlantic towards the Caribbean Sea and the Amazon basin. Along its transport path, the mineral dust is expected to influence significantly the radiation budget - by direct and indirect effects - of the subtropical North Atlantic. We are lacking a radiative closure in the Saharan air plume. One focus of the investigation within the trade wind region is the spatial distribution of mixed dust/biomass/sea salt aerosol and their physical and chemical properties, especially with regard to radiative effects. We report on measurements of size distributions, mass concentrations and mineralogical composition conducted at the Zagora (Morocco) and Praia (Cape Verde islands) ground stations. The aerosol size distribution was measured from 20 nm to 500

Geologic history of Cape Cod, Massachusetts

USGS Publications Warehouse

,

1976-01-01

Cape Cod, a sandy peninsula built mostly during the Ice Age, juts into the Atlantic Ocean like a crooked arm. Because of its exposed location, Cape Cod was visited by many early explorers. Although clear-cut evidence is lacking, the Vikings may have sighted this land about 1,000 years ago. It was visited by Samuel de Champlain in 1605, and his detailed descriptions and charts have helped present-day scientists to determine the rate of growth of Nauset Beach marsh and Nauset spit. Bartholomew Gosnold, a lesser known explorer, settled for a short time on the Elizabeth Islands to the southwest and gave Cape Cod its name in 1602. The Pilgrims first landed in America on the tip of Lower Cape Cod after they were turned back from their more southerly destination by shoals between Cape Cod and Nantucket Island. On Cape Cod they found potable water and food and had their first fight with the natives. The Pilgrims, however, decided that this land was too isolated, too exposed, and too sandy to support them, and they sailed across Cape Cod Bay to establish Plymouth. These features remain today. Small villages are separated by large areas of forest, dune, beach, and marsh. This unspoiled natural beauty makes Cape Cod one of the most favored vacation areas for the people living in the thickly settled Northeastern States. Cape Cod is of particular interest to geologists because it was formed by glaciers very recently in terms of geologic time. During the Great Ice Age, (the Pleistocene Epoch which began 2 to 3 million years ago), glaciers advanced from the north into the temperate regions of the Earth. Glacial ice covered the land at least four times. Each advance was accompanied by a worldwide lowering of sea level because the source of the ice was water from the seas. When the glaciers melted, the climate and sea level were probably much like they are today. In fact, some scientists believe that the Earth is presently between glacial episodes and that ice once again will advance across the land.

Impact of Sahara dust transport on Cape Verde atmospheric element particles.

PubMed

Almeida-Silva, M; Almeida, S M; Freitas, M C; Pio, C A; Nunes, T; Cardoso, J

2013-01-01

The objectives of this study were to (1) conduct an elemental characterization of airborne particles sampled in Cape Verde and (2) assess the influence of Sahara desert on local suspended particles. Particulate matter (PM(10)) was collected in Praia city (14°94'N; 23°49'W) with a low-volume sampler in order to characterize its chemical composition by k0-INAA. The filter samples were first weighed and subsequently irradiated at the Portuguese Research Reactor. Results showed that PM(10) concentrations in Cape Verde markedly exceeded the health-based air quality standards defined by the European Union (EU), World Health Organization (WHO), and U.S. Environmental Protection Agency (EPA), in part due to the influence of Sahara dust transport. The PM(10) composition was characterized essentially by high concentrations of elements originating from the soil (K, Sm, Co, Fe, Sc, Rb, Cr, Ce, and Ba) and sea (Na), and low concentrations of anthropogenic elements (As, Zn, and Sb). In addition, the high concentrations of PM measured in Cape Verde suggest that health of the population may be less affected compared with other sites where PM(10) concentrations are lower but more enriched with toxic elements.

Enhancement of caffeic acid phenethyl ester on all-trans retinoic acid-induced differentiation in human leukemia HL-60 cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuo, H.-C.; Kuo, W.-H.; Lee, Y.-J.

2006-10-01

All-trans retinoic acid (ATRA) induces complete remission in a high proportion of patients with acute promyelocytic leukemia (APL); however, the response is sometimes very slow. Furthermore, relapse and resistance to treatment often occur despite continued treatment with ATRA. Thereafter, combination treatment strategies have been suggested to circumvent these problems. The present study demonstrates that caffeic acid phenethyl ester (CAPE), a major component of honeybee propolis, enhanced ATRA-induced granulocytic differentiation in HL-60, a human promyelocytic cell line. The differentiation was assessed by Wright-Giemsa stain, nitroblue tetrazolium reduction, and membrane differentiation marker CD11b. In addition, CAPE enhanced ATRA-induced cell cycle arrest atmore » the G1 phase by decreasing the association of cdk2-cyclin E complex. Finally, it was demonstrated that CAPE promoted the ATRA-mediated nuclear transcription activation of RAR{alpha} assessed by EMSA assay and enhanced the expression of target genes including RAR{alpha}, C/EBP{epsilon}, and p21 protein resulting in the differentiation development of leukemia. It is suggested that CAPE possesses the potential to enhance the efficiency of ATRA in the differentiation therapy of APL.« less

A Controversial Reform in Indigenous Education: The Cape York Aboriginal Australian Academy

ERIC Educational Resources Information Center

McCollow, John

2012-01-01

This article examines a controversial initiative in Indigenous education: the establishment of the Cape York Aboriginal Australian Academy (CYAAA). The article provides a brief description of the Academy's three campuses and their communities and considers: the circumstances of its creation, including the role of Noel Pearson and Cape York…

33 CFR 80.120 - Cape Ann, MA to Marblehead Neck, MA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cape Ann, MA to Marblehead Neck, MA. 80.120 Section 80.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.120 Cape Ann, MA to...

33 CFR 80.120 - Cape Ann, MA to Marblehead Neck, MA.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Cape Ann, MA to Marblehead Neck, MA. 80.120 Section 80.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.120 Cape Ann, MA to...

33 CFR 80.120 - Cape Ann, MA to Marblehead Neck, MA.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Cape Ann, MA to Marblehead Neck, MA. 80.120 Section 80.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.120 Cape Ann, MA to...

33 CFR 80.120 - Cape Ann, MA to Marblehead Neck, MA.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Cape Ann, MA to Marblehead Neck, MA. 80.120 Section 80.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.120 Cape Ann, MA to...

33 CFR 80.120 - Cape Ann, MA to Marblehead Neck, MA.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Cape Ann, MA to Marblehead Neck, MA. 80.120 Section 80.120 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.120 Cape Ann, MA to...

Implementation of the U.S. Environmental Protection Agency's Waste Reduction (WAR) Algorithm in Cape-Open Based Process Simulators

EPA Science Inventory

The Sustainable Technology Division has recently completed an implementation of the U.S. EPA's Waste Reduction (WAR) Algorithm that can be directly accessed from a Cape-Open compliant process modeling environment. The WAR Algorithm add-in can be used in AmsterChem's COFE (Cape-Op...

33 CFR 80.501 - Tom's River, NJ to Cape May, NJ.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39°18.2′ N., longitude 74°33.1′ W. to the northeasternmost point of Ocean City at latitude 39°17.6′ N... from Cape May Inlet East Jetty Light 4 to Cape May Inlet West Jetty Light 5. [CGD 87-008b, 52 FR 25218...

33 CFR 80.501 - Tom's River, NJ to Cape May, NJ.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39°18.2′ N. longitude 74°33.1′ W. to the northeasternmost point of Ocean City at latitude 39°17.6′ N... from Cape May Inlet East Jetty Light 4 to Cape May Inlet West Jetty Light 5. [CGD 87-008b, 52 FR 25218...

77 FR 62257 - Draft Environmental Impact Statement for the Herring River Restoration Project, Cape Cod National...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-12

... Environmental Impact Statement for the Herring River Restoration Project, Cape Cod National Seashore... Herring River Restoration Project in Cape Cod National Seashore, Massachusetts. The DEIS provides a... a press release to area media. ADDRESSES: The DEIS for the Herring River Restoration Project will be...

77 FR 9852 - Special Regulations; Areas of the National Park System, Cape Cod National Seashore

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-21

... DEPARTMENT OF THE INTERIOR National Park Service 36 CFR Part 7 RIN 1024-AD88 Special Regulations; Areas of the National Park System, Cape Cod National Seashore AGENCY: National Park Service, Interior. ACTION: Final rule. SUMMARY: The National Park Service is amending special regulations for Cape Cod...

45. CAPE COD AIR STATION PAVE PAWS FACILITY BUILDING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

45. CAPE COD AIR STATION PAVE PAWS FACILITY - BUILDING ELEVATION VIEW WITH BUILDING METAL SIDING BEING APPLIED ON "A" FACE (LEFT) AND "B" FACE (RIGHT). NOTE THAT NORTH IS GENERALLY TO RIGHT OF VIEW. - Cape Cod Air Station, Technical Facility-Scanner Building & Power Plant, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

Promoting Distance Education in Higher Education in Cape Verde and Mozambique

ERIC Educational Resources Information Center

Ramos, Fernando; Taju, Gulamo; Canuto, Louisette

2011-01-01

Over the past six years, the authors have been project leaders for three distance education initiatives in Cape Verde and Mozambique: (1) a blended learning master's degree in multimedia in education for faculty in Cape Verdean public higher education institutions (2005-2008); (2) a teacher training programme for 1375 elementary teachers provided…

75 FR 52461 - Drawbridge Operation Regulation; Atlantic Intracoastal Waterway, Wrightsville Beach, NC and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-26

... Operation Regulation; Atlantic Intracoastal Waterway, Wrightsville Beach, NC and Northeast Cape Fear River... Bridge across the Northeast Cape Fear River, mile 1.0, at Wilmington, NC. The deviation is necessary to.... Holmes Bridge across the Northeast Cape Fear River, mile 1.0, at Wilmington. The current operating...

Cytoprotection of Human Endothelial Cells From Menadione Cytotoxicity by Caffeic Acid Phenethyl Ester: The Role of Heme Oxygenase-1

DTIC Science & Technology

2008-06-08

reported here show that CAPE induces HO-1 in human endothelial cells. The major signaling transduction involved in HO-1 induction by those electrophilic ...phenethyl ester (CAPE) and catechol ring- fluorinated CAPE derivatives against menadione-induced oxidative stress in human endothelial cells. Bioorganic

78 FR 49972 - Importation of Cape Gooseberry From Colombia Into the United States

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-16

... (Physalis peruviana) from Colombia is authorized for importation into the United States if the commodity is... added to read as follows: Sec. 319.56-60 Cape gooseberry from Colombia. Cape gooseberry (Physalis peruviana) may be imported into the United States from Colombia in accordance with the conditions described...

33 CFR 167.250 - In the approaches to the Cape Fear River: General.

Code of Federal Regulations, 2012 CFR

2012-07-01

... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.250 In the approaches to the Cape Fear River: General. The traffic separation scheme (TSS) in the approaches to the Cape Fear River...

33 CFR 167.250 - In the approaches to the Cape Fear River: General.

Code of Federal Regulations, 2013 CFR

2013-07-01

... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.250 In the approaches to the Cape Fear River: General. The traffic separation scheme (TSS) in the approaches to the Cape Fear River...

33 CFR 167.250 - In the approaches to the Cape Fear River: General.

Code of Federal Regulations, 2011 CFR

2011-07-01

... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.250 In the approaches to the Cape Fear River: General. The traffic separation scheme (TSS) in the approaches to the Cape Fear River...

33 CFR 167.250 - In the approaches to the Cape Fear River: General.

Code of Federal Regulations, 2014 CFR

2014-07-01

... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Atlantic East Coast § 167.250 In the approaches to the Cape Fear River: General. The traffic separation scheme (TSS) in the approaches to the Cape Fear River...

KSC-2014-3141

NASA Image and Video Library

2014-06-20

CAPE CANAVERAL, Fla. -- Reconstruction from the original architectural plans of the keeper's house, next to the historic Cape Canaveral Light on Cape Canaveral Air Force Station in Florida, is planned by the Cape Canaveral Lighthouse Foundation. The lighthouse currently is owned by the U.S. Air Force. The first lighthouse on Cape Canaveral was built near the tip of the Cape in 1848. The structure was only about 60 feet high with a rather dim light powered by whale oil. In 1859, work began nearby on a new, taller iron structure. Construction was halted during the Civil War, and the lighthouse was not finished until 1868. The structure, with a brick lining inside its iron exterior, was painted with its "daymark" black and white horizontal bands in 1873 to make it easier to identify during the day as a navigation point. Between 1892 and 1894, the lighthouse was dismantled and moved to a new location about a mile from the coast, where it stands today. For more information on the lighthouse, visit http://www.nasa.gov/centers/kennedy/about/history/lighthouse.html. Photo credit: NASA/Ben Smegelsky

Impacts of storms on coastal circulation in Long Bay, South Carolina

NASA Astrophysics Data System (ADS)

Kim, H.; Warner, J. C.; Voulgaris, G.; Work, P.

2006-12-01

We investigate the effects of coastal storms on the regional circulation in Long Bay, South Carolina, using a coupled ROMS (Regional Ocean Modeling System)- SWAN (Simulating WAves Nearshore) model. Meteorological observations during the South Carolina Coastal Erosion Study (October 2003 April 2004) reveal three dominant types of storms in the region warm fronts, cold fronts, and tropical storms. Each storm has a characteristic progression of wind patterns: (1) Warm fronts start with southwestward winds and change to northeastward after the front passes; (2) Cold fronts begin with northeastward winds and shift to southeastward when the front moves out; and (3) Tropical storms change wind directions from the southwest to the southeast during the storm. It is observed the coastal circulation distinctly responds to such atmospheric disturbances in either a upwelling-favorable condition to the northeastward winds or a downwelling-favorable condition to the southwestward winds. The study domain encompasses 300-km of gently arcing shoreline between Cape Romain to Cape Fear, and approximately 100-km offshore to the shelf edge. The model domain is resolved by a 300×130 mesh at 1-km intervals in the horizontal and twenty terrain-following layers in the vertical. The ROMS model is driven by tides and wind stress, and it includes wave-current interactions via dynamic coupling to the surface wave model SWAN. Salinity and temperature along the open boundaries are included by nudging to climatological values. A time period of six months is simulated from October 2003 to April 2004, concurrent with the observation study. Model results are compared to an extensive set of measurements collected at eight sites in the inner part of Long Bay, and are used to identify varying circulation response to each storm type. In addition, we investigate the significance of the Capes on the development of the alongshore pressure gradients, and examine the importance of wave-current interactions in the study region.

Alcohol, Methamphetamine, and Marijuana Exposure Have Distinct Effects on the Human Placenta.

PubMed

Carter, R Colin; Wainwright, Helen; Molteno, Christopher D; Georgieff, Michael K; Dodge, Neil C; Warton, Fleur; Meintjes, Ernesta M; Jacobson, Joseph L; Jacobson, Sandra W

2016-04-01

Animal studies have demonstrated adverse effects of prenatal alcohol exposure on placental development, but few studies have examined these effects in humans. Little is known about effects of prenatal exposure to methamphetamine, marijuana, and cigarette smoking on placental development. Placentas were collected from 103 Cape Coloured (mixed ancestry) pregnant women recruited at their first antenatal clinic visit in Cape Town, South Africa. Sixty-six heavy drinkers and 37 nondrinkers were interviewed about their alcohol, cigarette smoking, and drug use at 3 antenatal visits. A senior pathologist, blinded to exposure status, performed comprehensive pathology examinations on each placenta using a standardized protocol. In multivariable regression models, effects of prenatal exposure were examined on placental size, structure, and presence of infections and meconium. Drinkers reported a binge pattern of heavy drinking, averaging 8.0 drinks/occasion across pregnancy on 1.4 d/wk. 79.6% smoked cigarettes; 22.3% used marijuana; and 17.5% used methamphetamine. Alcohol exposure was related to decreased placental weight and a smaller placenta-to-birthweight ratio. By contrast, methamphetamine was associated with larger placental weight and a larger placenta-to-birthweight ratio. Marijuana was also associated with larger placental weight. Alcohol exposure was associated with increased risk of placental hemorrhage. Prenatal alcohol, drug, and cigarette use were not associated with chorioamnionitis, villitis, deciduitis, or maternal vascular underperfusion. Alcohol and cigarette smoking were associated with a decreased risk of intrauterine passing of meconium, a sign of acute fetal stress and/or hypoxia; methamphetamine, with an increased risk. This is the first human study to show that alcohol, methamphetamine, and marijuana were associated with distinct patterns of pathology, suggesting different mechanisms mediating their effects on placental development. Given the growing body of evidence linking placental abnormalities to neurodevelopmental deficits, these findings may be important in the long-term teratogenic effects of prenatal alcohol and drug exposure. Copyright © 2016 by the Research Society on Alcoholism.

Movement and fate of solutes in a plume of sewage-contaminated ground water, Cape Cod, Massachusetts

USGS Publications Warehouse

LeBlanc, D. R.

1984-01-01

The U.S. Geological Survey (USGS) has begun a nationwide program to study the fate of toxic wastes in groundwater. Several sites where groundwater is known to be contaminated are being studied by interdisciplinary teams of geohydrologists, chemists, and microbiologists. The objective of these studies is to obtain a thorough quantitative understanding of the physical, chemical, and biological processes of contaminant generation, migration, and attenuation in aquifers. One of the sites being studied by the USGS under this program is a plume of sewage contaminated groundwater on Cape Cod, Massachusetts. The plume was formed by land disposal of treated sewage to a glacial outwash aquifer since 1936. This report summarizes results obtained during the first year of research at the Cape Cod s under the USGS Toxic-Waste Ground-Water Contamination Program. The seven papers included in this volume were presented at the Toxic Waste Technical Meeting, Tucson, Arizona, in March 1984. They provide an integrated view of the subsurface distribution of contaminants based on the first year of research and discuss hypotheses concerning the transport processes that affect the movement of contaminants in the plume. (See W89-09053 thru W89-09059) (Lantz-PTT)

Associations between short-term exposure to nitrogen dioxide and mortality in 17 Chinese cities: the China Air Pollution and Health Effects Study (CAPES).

PubMed

Chen, Renjie; Samoli, Evangelia; Wong, Chit-Ming; Huang, Wei; Wang, Zongshuang; Chen, Bingheng; Kan, Haidong

2012-09-15

Few multi-city studies in Asian developing countries have examined the acute health effects of ambient nitrogen dioxide (NO(2)). In the China Air Pollution and Health Effects Study (CAPES), we investigated the short-term association between NO(2) and mortality in 17 Chinese cities. We applied two-stage Bayesian hierarchical models to obtain city-specific and national average estimates for NO(2). In each city, we used Poisson regression models incorporating natural spline smoothing functions to adjust for long-term and seasonal trend of mortality, as well as other time-varying covariates. We examined the associations by age, gender and education status. We combined the individual-city estimates of the concentration-response curves to get an overall NO(2)-mortality association in China. The averaged daily concentrations of NO(2) in the 17 Chinese cities ranged from 26 μg/m(3) to 67 μg/m(3). In the combined analysis, a 10-μg/m(3) increase in two-day moving averaged NO(2) was associated with a 1.63% [95% posterior interval (PI), 1.09 to 2.17], 1.80% (95% PI, 1.00 to 2.59) and 2.52% (95% PI, 1.44 to 3.59) increase of total, cardiovascular, and respiratory mortality, respectively. These associations remained significant after adjustment for ambient particles or sulfur dioxide (SO(2)). Older people appeared to be more vulnerable to NO(2) exposure. The combined concentration-response curves indicated a linear association. Conclusively, this largest epidemiologic study of NO(2) in Asian developing countries to date suggests that short-term exposure to NO(2) is associated with increased mortality risk. Copyright © 2012 Elsevier Ltd. All rights reserved.

Saving the child to save the nation: poverty, whiteness and childhood in the Cape Colony, c.1870-1895.

PubMed

Duff, S E

2011-01-01

Children were central to efforts to eradicate white impoverishment in the Cape Colony in the late nineteenth century. The education and training of poor, white children were believed to be the most effective ways of breaking cycles of poverty, and of ensuring continuing white control over the Cape's resources. Yet a closer reading of the evidence presented to the 1894 Labour Commission and the committee appointed to investigate the Destitute Children Relief Bill suggests that this interest in poor, white children also stemmed from concerns about the children themselves. Destitute white children - both male and female - were described, frequently, as representing a threat to the social, moral, and even economic order, and this view of poor white children shaped official responses to white poverty. This concern for white children reflected not solely their status as 'children' - that they represented the colony's future, were fairly malleable, and could be more easily 'reached' by projects and schemes to eradicate white poverty - but also their problematic class position in a colonial racial order that sought their reform, direction and education into acceptable productive citizens.

From warm to cold: migration of Adélie penguins within Cape Bird, Ross Island

NASA Astrophysics Data System (ADS)

Nie, Yaguang; Sun, Liguang; Liu, Xiaodong; Emslie, Steven D.

2015-06-01

Due to their sensitivity to environmental change, penguins in Antarctica are widely used as bio-indicators in paleoclimatic research. On the basis of bio-element assemblages identified in four ornithogenic sediment profiles, we reconstructed the historical penguin population change at Cape Bird, Ross Island, for the past 1600 years. Clear succession of penguin population peaks were observed in different profiles at about 1400 AD, which suggested a high probability of migration within this region. The succession was most obviously marked by a sand layer lasting from 1400 to 1900 AD in one of the analyzed profiles. Multiple physical/chemical parameters indicated this sand layer was not formed in a lacustrine environment, but was marine-derived. Both isostatic subsidence and frequent storms under the colder climatic condition of the Little Ice Age were presumed to have caused the abandonment of the colonies, and we believe the penguins migrated from the coastal area of mid Cape Bird northward and to higher ground as recorded in the other sediment profiles. This migration was an ecological response to global climate change and possible subsequent geological effects in Antarctica.

KSC-2012-4353

NASA Image and Video Library

2012-08-10

CAPE CANAVERAL, Fla. – The Radiation Belt Storm Probes, or RBSP, spacecraft are moved inside their payload fairing on the payload transporter from the Astrotech payload processing facility in Titusville, Fla. to Space Launch Complex-41 at Cape Canaveral Air Force Station. The fairing, which holds the twin RBSP spacecraft, will be lifted to the top of a United Launch Alliance Atlas V rocket for launch later in August. The two spacecraft are designed to study the Van Allen radiation belts in unprecedented detail. Photo credit: NASA/Dmitri Gerondidakis

Earth observations taken from shuttle orbiter Columbia

NASA Image and Video Library

1995-10-24

STS073-725-031 (24 October 1995) --- The contrasting colors of fall in New England are captured on this northward-looking photo of Martha's Vineyard, Nantucket Island, and the famous hook-shaped Cape Cod. Light-colored patches of urbanization are scattered throughout the scene, the most evident being the greater Boston area along the shores of Massachusetts Bay. The cape is composed of rock debris that, according to NASA scientists studying Columbia's photo collection, was deposited along the end of glacier some 20,000 years ago.

KSC-06pd0456

NASA Image and Video Library

2006-01-26

KENNEDY SPACE CENTER, FLA. - At Cape Canaveral Air Force Station, workers help place the lamp room detached from the Cape Canaveral Lighthouse onto a flat bed truck. It will be moved to a facility near Cape Canaveral for repairs and renovation. Leaks in the roof allowed moisture to seep in. The lamp room is being removed for repairs and refurbishment. In addition, the original brass roof will be restored and put back in place. The Cape Canaveral Lighthouse is the only operational lighthouse owned by the Air Force. It was first erected in 1868 near the edge of the Atlantic Ocean. Photo credit: NASA/Jack Pfaller

KSC-06pd0457

NASA Image and Video Library

2006-01-26

KENNEDY SPACE CENTER, FLA. - At Cape Canaveral Air Force Station, workers secure the lamp room detached from the Cape Canaveral Lighthouse onto a flat bed truck. Leaks in the roof allowed moisture to seep in. The lamp room will be moved to a facility near Cape Canaveral for repairs and renovation. The lamp room is being removed for repairs and refurbishment. In addition, the original brass roof will be restored and put back in place. The Cape Canaveral Lighthouse is the only operational lighthouse owned by the Air Force. It was first erected in 1868 near the edge of the Atlantic Ocean. Photo credit: NASA/Jack Pfaller

Social constructions of gender roles, gender-based violence and HIV/AIDS in two communities of the Western Cape, South Africa.

PubMed

Strebel, A; Crawford, M; Shefer, T; Cloete, A; Henda, N; Kaufman, M; Simbayi, L; Magome, K; Kalichman, S

2006-11-01

The links between gender roles, gender-based violence and HIV/AIDS risk are complex and culturally specific. In this qualitative study we investigated how women and men in two black communities in the Western Cape, South Africa, constructed their gender identities and roles, how they understood gender-based violence, and what they believed about the links between gender relations and HIV risk. First we conducted 16 key informant interviews with members of relevant stakeholder organisations. Then we held eight focus group discussions with community members in single-sex groups. Key findings included the perception that although traditional gender roles were still very much in evidence, shifts in power between men and women were occurring. Also, gender-based violence was regarded as a major problem throughout communities, and was seen to be fuelled by unemployment, poverty and alcohol abuse. HIV/AIDS was regarded as particularly a problem of African communities, with strong themes of stigma, discrimination, and especially 'othering' evident. Developing effective HIV/AIDS interventions in these communities will require tackling the overlapping as well as divergent constructions of gender, gender violence and HIV which emerged in the study.

Community perceptions of risk factors for interpersonal violence in townships in Cape Town, South Africa: A focus group study.

PubMed

Makanga, Prestige Tatenda; Schuurman, Nadine; Randall, Ellen

2017-10-01

Interpersonal violence is a major contributor to the burden of disease globally, and in South Africa, it is the leading cause of injury. There is an emerging consensus that the development of actionable policy and effective prevention strategies for interpersonal violence requires an understanding of the contextual matters that elevate risk for interpersonal violence. The objective of this study was to explore community perceptions of risks for interpersonal violence in five townships in Cape Town, South Africa, with high rates of violence. Focus group discussions were conducted with community members to identify key factors in that contributed to being either a perpetrator or victim of interpersonal violence. The ecological framework was used to classify the risk factors as occurring at individual, relationship, community or society levels. Some of the risk factors identified included alcohol abuse, poverty, informality of settlements and cultural norms. Differences in how each of these risk factors are expressed and experienced in the five communities are also elucidated. This approach enabled the collection of contextual community-based data that can complement conventional surveillance data in the development of relevant community-level strategies for interpersonal violence prevention.

75 FR 33999 - Safety Zone; Fourth of July Fireworks Event, Cape Charles City Harbor, Cape Charles, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

...: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a 420-foot..., and falling hot embers or other debris, vessel traffic will be temporarily restricted within 420 feet... navigable waters of the Cape Charles City Harbor within the area bounded by a 420-foot radius circle...

Developing a Strategic Approach to Social Responsiveness at the University of Cape Town, South Africa

ERIC Educational Resources Information Center

Favish, Judith; McMillan, Janice; Ngcelwane, Sonwabo V.

2012-01-01

Collaborative community-engaged scholarship has roots in many parts of the world, and engaged practitioners and researchers are increasingly finding each other and sharing resources globally. This article focuses on a "social responsiveness" initiative at the University of Cape Town. Its story, told here by three University of Cape Town…

46 CFR 7.10 - Eastport, ME to Cape Ann, MA.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Eastport, ME to Cape Ann, MA. 7.10 Section 7.10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.10 Eastport, ME to Cape Ann, MA. (a) A line drawn from the easternmost extremity of Kendall...

46 CFR 7.10 - Eastport, ME to Cape Ann, MA.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Eastport, ME to Cape Ann, MA. 7.10 Section 7.10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.10 Eastport, ME to Cape Ann, MA. (a) A line drawn from the easternmost extremity of Kendall...

46 CFR 7.10 - Eastport, ME to Cape Ann, MA.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Eastport, ME to Cape Ann, MA. 7.10 Section 7.10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.10 Eastport, ME to Cape Ann, MA. (a) A line drawn from the easternmost extremity of Kendall...

46 CFR 7.10 - Eastport, ME to Cape Ann, MA.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Eastport, ME to Cape Ann, MA. 7.10 Section 7.10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.10 Eastport, ME to Cape Ann, MA. (a) A line drawn from the easternmost extremity of Kendall...

46 CFR 7.10 - Eastport, ME to Cape Ann, MA.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Eastport, ME to Cape Ann, MA. 7.10 Section 7.10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.10 Eastport, ME to Cape Ann, MA. (a) A line drawn from the easternmost extremity of Kendall...

75 FR 34152 - Record of Decision for the Cape Wind Energy Project; Secretary of the Interior's Response to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

... Energy Project; Secretary of the Interior's Response to Comments From the Advisory Council on Historic Preservation on the Cape Wind Energy Project AGENCY: Minerals Management Service, Interior. ACTION: Notice of... announcing the availability of the ROD for the Cape Wind Energy Project (the Project). The ROD for the...

33 CFR 80.505 - Cape Henlopen, DE to Cape Charles, VA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... to Cape Charles, VA. (a) A line drawn from the seaward extremity of Indian River Inlet North Jetty to Indian River Inlet South Jetty Light. (b) A line drawn from Ocean City Inlet Light 6, 225° true across Ocean City Inlet to the submerged south breakwater. (c) A line drawn from Assateague Beach Tower Light...

46. CAPE COD AIR STATION PAVE PAWS FACILITY BUILDING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

46. CAPE COD AIR STATION PAVE PAWS FACILITY - BUILDING ELEVATION VIEW WITH ALL METAL SIDING INSTALLED AND WITH EMITTER/ANTENNA ARRAY SYSTEM NEARING OCMPLETION ON "B" FACE (RIGHT). VIEW ALSO SHOWS TRAVELING "CLEANING" SYSTEM ON "B" FACE - NOW REMOVED. - Cape Cod Air Station, Technical Facility-Scanner Building & Power Plant, Massachusetts Military Reservation, Sandwich, Barnstable County, MA

Strategies for Post-Primary Education in Small Island Developing States (SIDS): Lessons from Cape Verde

ERIC Educational Resources Information Center

Atchoarena, David; Da Graca, Patricia Dias; Marquez, Jose Manuel

2008-01-01

This article addresses the context and challenges of small island developing states, focusing particularly on Cape Verde. After a general discussion of the characteristics of small island developing states, several development challenges such as poverty, unemployment and migratory issues specific to Cape Verde are evoked. Despite a period of…

Cape Verde. A Country Guide Series Report from the AACRAO-AID Project.

ERIC Educational Resources Information Center

Sevigny, Joseph A.

This report provides information on the education system of Cape Verde, and is designed to assist college admissions officers and registrars in the United States with the admission and placement of students from that country. The report contains general information on the geography, history, and people of Cape Verde, as well as more specific…

Cape Verdeans in America: Our Story.

ERIC Educational Resources Information Center

Almeida, Raymond Anthony, Ed.

Immigration and acculturation of Cape Verdeans in the United States from the mid-19th century to the present are discussed. Emphasis is on the period prior to 1922, at which time the United States Congress enacted new laws restricting the immigration of people of color. The Cape Verde islands are located in the Atlantic off the coast of West…

46 CFR 7.160 - Point Whitshed, AK to Aialik Cape, AK.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Point Whitshed, AK to Aialik Cape, AK. 7.160 Section 7.160 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.160 Point Whitshed, AK to Aialik Cape, AK. (a) A line drawn from the southernmost...

46 CFR 7.160 - Point Whitshed, AK to Aialik Cape, AK.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Point Whitshed, AK to Aialik Cape, AK. 7.160 Section 7.160 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.160 Point Whitshed, AK to Aialik Cape, AK. (a) A line drawn from the southernmost...

46 CFR 7.160 - Point Whitshed, AK to Aialik Cape, AK.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Point Whitshed, AK to Aialik Cape, AK. 7.160 Section 7.160 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.160 Point Whitshed, AK to Aialik Cape, AK. (a) A line drawn from the southernmost...

46 CFR 7.160 - Point Whitshed, AK to Aialik Cape, AK.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Point Whitshed, AK to Aialik Cape, AK. 7.160 Section 7.160 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.160 Point Whitshed, AK to Aialik Cape, AK. (a) A line drawn from the southernmost...

46 CFR 7.160 - Point Whitshed, AK to Aialik Cape, AK.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Point Whitshed, AK to Aialik Cape, AK. 7.160 Section 7.160 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.160 Point Whitshed, AK to Aialik Cape, AK. (a) A line drawn from the southernmost...

76 FR 49726 - Notice of Availability of a Pest Risk Analysis for the Importation of Fresh Cape Gooseberry Fruit...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-11

... Cape gooseberry fruit (Physalis peruviana L.), with husks, to be imported from Chile into the... with the importation into the continental United States of fresh Cape gooseberry fruit (Physalis peruviana L.) with husks from Chile. Based on this analysis, we concluded that the application of one or...

33 CFR 80.501 - Tom's River, NJ to Cape May, NJ.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Tom's River, NJ to Cape May, NJ. 80.501 Section 80.501 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Fifth District § 80.501 Tom's River, NJ to Cape May, NJ...

Competition and feeding ecology in two sympatric Xenopus species (Anura: Pipidae)

PubMed Central

Vogt, Solveig; de Villiers, F. André; Ihlow, Flora; Rödder, Dennis

2017-01-01

The widespread African clawed frog (Xenopus laevis) occurs in sympatry with the IUCN Endangered Cape platanna (Xenopus gilli) throughout its entire range in the south-western Cape, South Africa. In order to investigate aspects of the interspecific competition between populations of X. laevis and X. gilli, an assessment of their niche differentiation was conducted through a comprehensive study on food composition and trophic niche structure at two study sites: the Cape of Good Hope (CoGH) and Kleinmond. A total of 399 stomach contents of X. laevis (n = 183) and X. gilli (n = 216) were obtained together with samples of available prey to determine food preferences using the Electivity index (E*), the Simpson’s index of diversity (1 − D), the Shannon index (H′), and the Pianka index (Ojk). Xenopus gilli diet was more diverse than X. laevis, particularly in Kleimond where the Shannon index was nearly double. Both species were found to consume large amounts of tadpoles belonging to different amphibian species, including congeners, with an overall higher incidence of anurophagy than previously recorded. However, X. laevis also feeds on adult X. gilli, thus representing a direct threat for the latter. While trophic niche overlap was 0.5 for the CoGH, it was almost 1 in Kleinmond, suggesting both species utilise highly congruent trophic niches. Further, subdividing the dataset into three size classes revealed overlap to be higher in small frogs in both study sites. Our study underlines the importance of actively controlling X. laevis at sites with X. gilli in order to limit competition and predation, which is vital for conservation of the south-western Cape endemic. PMID:28439453

Behavioural and chemical evidence for multiple colonisation of the Argentine ant, Linepithema humile, in the Western Cape, South Africa

PubMed Central

2011-01-01

Background The Argentine ant, Linepithema humile, is a widespread invasive ant species that has successfully established in nearly all continents across the globe. Argentine ants are characterised by a social structure known as unicoloniality, where territorial boundaries between nests are absent and intraspecific aggression is rare. This is particularly pronounced in introduced populations and results in the formation of large and spatially expansive supercolonies. Although it is amongst the most well studied of invasive ants, very little work has been done on this ant in South Africa. In this first study, we investigate the population structure of Argentine ants in South Africa. We use behavioural (aggression tests) and chemical (CHC) approaches to investigate the population structure of Argentine ants within the Western Cape, identify the number of supercolonies and infer number of introductions. Results Both the aggression assays and chemical data revealed that the Western Cape Argentine ant population can be divided into two behaviourally and chemically distinct supercolonies. Intraspecific aggression was evident between the two supercolonies of Argentine ants with ants able to discriminate among conspecific non-nestmates. This discrimination is linked to the divergence in cuticular hydrocarbon profiles of ants originating from the two supercolonies. Conclusions The presence of these two distinct supercolonies is suggestive of at least two independent introductions of this ant within the Western Cape. Moreover, the pattern of colonisation observed in this study, with the two colonies interspersed, is in agreement with global patterns of Argentine ant invasions. Our findings are of interest because recent studies show that Argentine ants from South Africa are different from those identified in other introduced ranges and therefore provide an opportunity to further understand factors that determine the distributional and spread patterns of Argentine ant supercolonies. PMID:21288369

KSC-01pp1053

NASA Image and Video Library

2001-05-31

The first stage of the Geostationary Operational Environmental Satellite-M (GOES-M) Atlas II rocket is lifted to a vertical position at the gantry on Complex 36-A, Cape Canaveral Air Force Station. It will be raised and lifted up the gantry for mating with other stages. The last in the current series of advanced geostationary weather satellites in service, GOES-M has a new instrument not on earlier spacecraft, a Solar X-ray Imager that can be used in forecasting space weather, the effects of solar storms that create electromagnetic disturbances on earth that affect other satellites, communications and power grids. GOES-M is scheduled to launch from Cape Canaveral Air Force Station July 15

KSC-01PP1054

NASA Image and Video Library

2001-05-31

The first stage of the Geostationary Operational Environmental Satellite-M (GOES-M) Atlas II rocket is raised to a nearly vertical position on the gantry on Complex 36-A, Cape Canaveral Air Force Station. It will be raised and lifted up the gantry for mating with other stages. The last in the current series of advanced geostationary weather satellites in service, GOES-M has a new instrument not on earlier spacecraft, a Solar X-ray Imager that can be used in forecasting space weather, the effects of solar storms that create electromagnetic disturbances on earth that affect other satellites, communications and power grids. GOES-M is scheduled to launch from Cape Canaveral Air Force Station July 15

KSC-01pp1064

NASA Image and Video Library

2001-06-02

KENNEDY SPACE CENTER, Fla. -- At Complex 36-A, Cape Canaveral Air Force Station, the second stage of the Geostationary Operational Environmental Satellite-M (GOES-M) Atlas II rocket is lifted from the transporter. It will be raised to vertical and lifted up the gantry for mating with the first stage. The last in the current series of advanced geostationary weather satellites in service, GOES-M has a new instrument not on earlier spacecraft, a Solar X-ray Imager that can be used in forecasting space weather, the effects of solar storms that create electromagnetic disturbances on earth that affect other satellites, communications and power grids. GOES-M is scheduled to launch from Cape Canaveral Air Force Station July 15

Radon as a tracer of biogenic gas equilibration and transport from methane-saturated sediments

NASA Technical Reports Server (NTRS)

Martens, Christopher S.; Chanton, Jeffrey P.

1989-01-01

Data on Rn-222 activity in methane-rich gas bubbles from anoxic coastal sediments of Cape Lookout Bight, North Carolina, were used to determine gas equilibration with pore waters and the rates of ebullitive stripping and transport of gases to overlying waters and the atmosphere. Results showed that, during summer months, the bubble ebullition process strips and transports 1.9-4.8 percent/day of the standing crop of radon (and, by inference, other gases equilibrated with gas bubbles) in surface sediments of Cape Lookout Bight to the troposphere. Thus, the ebullitive mode of gas transport represents an effective mechanism for delivering reduced biogenic gases directly to the atmosphere.

Antiproliferative activity and SARs of caffeic acid esters with mono-substituted phenylethanols moiety.

PubMed

Xie, Jin; Yang, Fengzhi; Zhang, Man; Lam, Celine; Qiao, Yixue; Xiao, Jia; Zhang, Dongdong; Ge, Yuxuan; Fu, Lei; Xie, Dongsheng

2017-01-15

A series of CAPE derivatives with mono-substituted phenylethanols moiety were synthesized and evaluated by MTT assay on growth of 4 human cancer cell lines (Hela, DU-145, MCF-7 and ECA-109). The substituent effects on the antiproliferative activity were systematically investigated for the first time. It was found that electron-donating and hydrophobic substituents at 2'-position of phenylethanol moiety could significantly enhance CAPE's antiproliferative activity. 2'-Propoxyl derivative, as a novel caffeic acid ester, exhibited exquisite potency (IC 50 =0.4±0.02 & 0.6±0.03μM against Hela and DU-145 respectively). Copyright © 2016 Elsevier Ltd. All rights reserved.

Earth observations during STS-89 mission

NASA Image and Video Library

1998-01-31

STS089-706-068 (22-31 Jan. 1998) --- This nadir view of the southern Cape District of South Africa was photographed with a 70mm handheld camera from the Earth-orbiting space shuttle Endeavour. Prominent landmarks are the Cape of Good Hope, False Bay and Cape Town. Cape Town is the gray area at the base of the peninsula that forms the Cape of Good Hope. East and north of Cape Town the dark mountain ranges are the Cape Fold Belt. Northerly structures of the region formed approximately 580 million years ago when east Antarctica, Africa and parts of South America combined. According to NASA scientists those continents separated and then recombined about 230 million years ago; in the later event, the northerly structures were again active and the west-trending folds of the Great and Little Karroo ranges formed. The westerly structures of the Karroo formed somewhat later; the northerly structures were re-folded at that time. The great continental mass, Gondwana, remained together until around 175 million years ago, when it rifted apart leaving the coastline essentially as it is seen today. Photos such as this are useful to geologists working in these areas as they provide, quite literally, the big picture in complex regions. Other items of interest are the internal waves noted offshore, several trains can be seen east, north and south of Cape Town. In the mountains to the north (upper left corner) a large brush fire is seen from the smoke plume. The giant gold and diamond mines are located northeast and east of this photo. The gold province is primarily located around Johannesburg (450 miles northeast) and the diamond mines are approximately 300 miles northeast around Kimberley. Photo credit: NASA

Origin and Population Dynamics of a Novel HIV-1 Subtype G Clade Circulating in Cape Verde and Portugal

PubMed Central

Guimarães, Monick L.; Morgado, Mariza G.; Bello, Gonzalo

2015-01-01

The human immunodeficiency virus type 1 (HIV-1) subtype G is the most prevalent and second most prevalent HIV-1 clade in Cape Verde and Portugal, respectively; but there is no information about the origin and spatiotemporal dispersal pattern of this HIV-1 clade circulating in those countries. To this end, we used Maximum Likelihood and Bayesian coalescent-based methods to analyze a collection of 578 HIV-1 subtype G pol sequences sampled throughout Portugal, Cape Verde and 11 other countries from West and Central Africa over a period of 22 years (1992 to 2013). Our analyses indicate that most subtype G sequences from Cape Verde (80%) and Portugal (95%) branched together in a distinct monophyletic cluster (here called GCV-PT). The GCV-PT clade probably emerged after a single migration of the virus out of Central Africa into Cape Verde between the late 1970s and the middle 1980s, followed by a rapid dissemination to Portugal a couple of years later. Reconstruction of the demographic history of the GCV-PT clade circulating in Cape Verde and Portugal indicates that this viral clade displayed an initial phase of exponential growth during the 1980s and 1990s, followed by a decline in growth rate since the early 2000s. Our data also indicate that during the exponential growth phase the GCV-PT clade recombined with a preexisting subtype B viral strain circulating in Portugal, originating the CRF14_BG clade that was later disseminated to Spain and Cape Verde. Historical and recent human population movements between Angola, Cape Verde and Portugal probably played a key role in the origin and dispersal of the GCV-PT and CRF14_BG clades. PMID:25993094

Origin and Population Dynamics of a Novel HIV-1 Subtype G Clade Circulating in Cape Verde and Portugal.

PubMed

de Pina-Araujo, Isabel Inês M; Delatorre, Edson; Guimarães, Monick L; Morgado, Mariza G; Bello, Gonzalo

2015-01-01

The human immunodeficiency virus type 1 (HIV-1) subtype G is the most prevalent and second most prevalent HIV-1 clade in Cape Verde and Portugal, respectively; but there is no information about the origin and spatiotemporal dispersal pattern of this HIV-1 clade circulating in those countries. To this end, we used Maximum Likelihood and Bayesian coalescent-based methods to analyze a collection of 578 HIV-1 subtype G pol sequences sampled throughout Portugal, Cape Verde and 11 other countries from West and Central Africa over a period of 22 years (1992 to 2013). Our analyses indicate that most subtype G sequences from Cape Verde (80%) and Portugal (95%) branched together in a distinct monophyletic cluster (here called G(CV-PT)). The G(CV-PT) clade probably emerged after a single migration of the virus out of Central Africa into Cape Verde between the late 1970s and the middle 1980s, followed by a rapid dissemination to Portugal a couple of years later. Reconstruction of the demographic history of the G(CV-PT) clade circulating in Cape Verde and Portugal indicates that this viral clade displayed an initial phase of exponential growth during the 1980s and 1990s, followed by a decline in growth rate since the early 2000s. Our data also indicate that during the exponential growth phase the G(CV-PT) clade recombined with a preexisting subtype B viral strain circulating in Portugal, originating the CRF14_BG clade that was later disseminated to Spain and Cape Verde. Historical and recent human population movements between Angola, Cape Verde and Portugal probably played a key role in the origin and dispersal of the G(CV-PT )and CRF14_BG clades.

Evaluating the Photoprotective Effects of Ochre on Human Skin by In Vivo SPF Assessment: Implications for Human Evolution, Adaptation and Dispersal

PubMed Central

Rifkin, Riaan F.; Dayet, Laure; Queffelec, Alain; Summers, Beverley; Lategan, Marlize; d’Errico, Francesco

2015-01-01

Archaeological indicators of cognitively modern behaviour become increasingly prevalent during the African Middle Stone Age (MSA). Although the exploitation of ochre is viewed as a key feature of the emergence of modern human behaviour, the uses to which ochre and ochre-based mixtures were put remain ambiguous. Here we present the results of an experimental study exploring the efficacy of ochre as a topical photoprotective compound. This is achieved through the in vivo calculation of the sun protection factor (SPF) values of ochre samples obtained from Ovahimba women (Kunene Region, Northern Namibia) and the Palaeozoic Bokkeveld Group deposits of the Cape Supergroup (Western Cape Province, South Africa). We employ visible spectroscopy, energy-dispersive X-ray fluorescence (ED-XRF), X-ray diffraction (XRD) and granulometric analyses to characterise ochre samples. The capacity of ochre to inhibit the susceptibility of humans to the harmful effects of exposure to ultraviolet radiation (UVR) is confirmed and the mechanisms implicated in the efficacy of ochre as a sunscreen identified. It is posited that the habitual application of ochre may have represented a crucial innovation for MSA humans by limiting the adverse effects of ultraviolet exposure. This may have facilitated the colonisation of geographic regions largely unfavourable to the constitutive skin colour of newly arriving populations. PMID:26353012

Coordinated Field Campaigns in Chesapeake Bay and Gulf of Mexico

NASA Technical Reports Server (NTRS)

Mannino, Antonio; Novak, Michael; Tzortziou, Maria A.

2015-01-01

NASA's GEOstationary Coastal and Air Pollution Events (GEO-CAPE) mission concept recommended by the U.S. National Research Council (2007) focuses on measurements of atmospheric trace gases and aerosols and aquatic coastal ecology and biogeochemistry from geostationary orbit (35,786 km altitude). Two GEO-CAPE-sponsored multi-investigator ship-based field campaigns were conducted to coincide with the NASA Earth Venture Suborbital project DISCOVER-AQ (Deriving Information on Surface conditions from Column and Vertically Resolved Observations Relevant to Air Quality) field campaigns: (1) Chesapeake Bay in July 2011 and (2) northwestern Gulf of Mexico in September 2013. Goal: to evaluate whether GEO-CAPE coastal mission measurement and instrument requirements are optimized to address science objectives while minimizing ocean color satellite sensor complexity, size and cost - critical mission risk reduction activities. NASA continues to support science studies related to the analysis of data collected as part of these coordinated field campaigns and smaller efforts.

Persistent Organochlorine Pesticide Exposure Related to a Formerly Used Defense Site on St. Lawrence Island, Alaska: Data from Sentinel Fish and Human Sera.

PubMed

Byrne, Samuel; Miller, Pamela; Waghiyi, Viola; Buck, C Loren; von Hippel, Frank A; Carpenter, David O

2015-01-01

St. Lawrence Island, Alaska, is the largest island in the Bering Sea, located 60 km from Siberia. The island is home to approximately 1600 St. Lawrence Island Yupik residents who live a subsistence way of life. Two formerly used defense sites (FUDS) exist on the island, one of which, Northeast Cape, has been the subject of a $123 million cleanup effort. Environmental monitoring demonstrates localized soil and watershed contamination with polychlorinated biphenyls (PCB), organochlorine (OC) pesticides, mercury, and arsenic. This study examined whether the Northeast Cape FUDS is a source of exposure to OC pesticides. In total, 71 serum samples were collected during site remediation from volunteers who represented three geographic regions of the island. In addition, ninespine stickleback (Pungitius pungitius) and Alaska blackfish (Dallia pectoralis) were collected from Northeast Cape after remediation to assess continuing presence of OC pesticides. Chlordane compounds, DDT compounds, mirex, and hexachlorobenzene (HCB) were the most prevalent and present at the highest concentrations in both fish tissues and human serum samples. After controlling for age and gender, activities near the Northeast Cape FUDS were associated with an increase in serum HCB as compared to residents of the farthest village from the site. Positive but nonsignificant relationships for sum-chlordane and sum-DDT were also found. Organochlorine concentrations in fish samples did not show clear geographic trends, but appear elevated compared to other sites in Alaska. Taken together, data suggest that contamination of the local environment at the Northeast Cape FUDS may increase exposure to select persistent OC pesticides.

Persistent organochlorine pesticide exposure related to a formerly used defense site on St. Lawrence Island, Alaska: data from sentinel fish and human sera

PubMed Central

Byrne, Samuel; Miller, Pamela; Waghiyi, Viola; Buck, C. Loren; von Hippel, Frank A.; Carpenter, David O.

2015-01-01

St. Lawrence Island, Alaska is the largest island in the Bering Sea, located 60 km from Siberia. The island is home to approximately 1600 St. Lawrence Island Yupik residents who live a subsistence lifestyle. Two formerly used defense sites (FUDS) exist on the island, one of which, Northeast Cape, has been the subject of a $123 million cleanup effort. Environmental monitoring demonstrates localized soil and watershed contamination with polychlorinated biphenyls (PCBs), organochlorine (OC) pesticides and arsenic. This study examined whether the Northeast Cape FUDS is a source of exposure to OC pesticides. A total of 71 serum samples were collected during site remediation from volunteers that represented three geographic regions of the island. Additionally, ninespine stickleback (Pungitius pungitius) and Alaska blackfish (Dallia pectoralis) were collected from Northeast Cape after remediation to assess continuing presence of OC pesticides. Chlordane compounds, DDT compounds, mirex and hexachlorobenzene (HCB) were the most prevalent and present at the highest concentrations in both fish tissues and human serum samples. After controlling for age and sex, activities near the Northeast Cape FUDS were associated with an increase in serum HCB as compared to residents of the farthest village from the site. Positive but non-significant relationships for sum-chlordane and sum-DDT were also found. Organochlorine concentrations in fish samples did not show clear geographic trends, but appear elevated compared to other sites in Alaska. Taken together, the results suggest that contamination of the local environment at the Northeast Cape FUDS may increase exposure to select persistent OC pesticides. PMID:26262441

Pharmacists’ Opinions of the Value of CAPE Outcomes in Hiring Decisions

PubMed Central

Marsh, Wallace A.; Castleberry, Ashley N.; Kelley, Katherine A.; Boyce, Eric G.

2017-01-01

Objective. The Hiring Intent Reasoning Examination (HIRE) was designed to explore the utility of the CAPE 2013 outcomes attributes from the perspective of practicing pharmacists, examine how each attribute influences hiring decisions, and identify which of the attributes are perceived as most and least valuable by practicing pharmacists. Methods. An electronic questionnaire was developed and distributed to licensed pharmacists in four states to collect their opinions about 15 CAPE subdomains plus five additional business related attributes. The attributes that respondents identified were: necessary to be a good pharmacist, would impact hiring decisions, most important to them, and in short supply in the applicant pool. Data were analyzed using statistical analysis software to determine the relative importance of each to practicing pharmacists and various subsets of pharmacists. Results. The CAPE subdomains were considered necessary for most jobs by 51% or more of the 3723 respondents (range, 51% to 99%). The necessity for business-related attributes ranged from 21% to 92%. The percentage who would not hire an applicant who did not possess the attribute ranged from 2% to 71.5%; the percentage who considered the attribute most valuable ranged from 0.3% to 35%; and the percentage who felt the attribute was in short supply ranged from 5% to 36%. Opinions varied depending upon gender, practice setting and whether the pharmacist was an employee or employer. Conclusion. The results of this study can be used by faculty and administrators to inform curricular design and emphasis on CAPE domains and business-related education in pharmacy programs. PMID:29367774

The utilization of health care services by children with Foetal Alcohol Syndrome in the Western Cape, South Africa.

PubMed

Credé, Sarah; Sinanovic, Edina; Adnams, Colleen; London, Leslie

2011-06-01

The rates of Foetal Alcohol Syndrome (FAS) and Partial Foetal Alcohol Spectrum (PFAS) in South Africa are the highest reported worldwide. There is a paucity of research examining the health care costs of caring for children with FAS or PFAS in this country. A cross-sectional analytical study was conducted using an interviewer-administered questionnaire amongst caregivers of children (0-12 years) with FAS/PFAS in the Western Cape to estimate the utilization of health care services; the annual direct and indirect health care costs per child as well as the total cost to society for providing health care services to children with FAS/PFAS. It was found that the median number of annual visits to public health care facilities per child was 8 (IQR 4 to 14). The total average annual cost per child was $1039.38 (95% CI: $808.68; $1270.07) and the total annual societal cost for the Western Cape was $70,960,053.68 (95% CI: $5,528,895.48; $86,709,971.13). Caregivers in receipt of a social support grant reported spending significantly less on health care for a child with FAS/PFAS (Fisher's exact p=0.004). These study results confirm the significant burden of FAS/PFAS on the Western Cape economy and the health care system which has significant implications for FAS prevention. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

White whale ( Delphinapterus leucas) distribution in Onega Bay of the White Sea in the summer

NASA Astrophysics Data System (ADS)

Andrianov, V. V.; Bel'Kovich, V. M.; Lukin, L. R.

2009-02-01

Data on the white whale distribution in Onega Bay of the White Sea obtained during route and stationary observations in the summer of 2003-2006 are given. The presence of three regions of summer habitation of local “nonmigratory” white whale reproductive schools is confirmed. The minimum abundance of the “zhizhginskoe” (northeastern) school is 60 individuals, and the minimum abundance of the “myagostrovskoe” (western) is 50 individuals. The abundance of the best studied “southern” school is close to 120-130 individuals. One more region of white whale concentration (with an abundance of up to 40 individuals) (the eastern one; Cape Letniy Orlov-Cape Chesmenskiy) was found. The localization of single reproductive schools (RS) is due to a number of factors: the morphometry of the shores and bottom, the hydrological regime, and the character of the coastal tidal currents. The white whale distribution in the southern part of Onega Bay in the summer (June-July) is of discontinuous character with concentrations near cape Glubokiy and some other adjacent parts. The coefficient of the white whale attendance in the Cape Glubokiy area varied from 42.5 to 67.4% during the years of the studies (2003-2006). The character of the distribution, the direction of the relocations, and the animals’ behavior peculiarities indicate that the white whales of the southern part of Onega Bay of the White Sea form a rather stable school community of a few (5-6) locally distributed small family groups during the summer.

33 CFR 334.100 - Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range. 334.100 Section 334.100 Navigation and Navigable Waters CORPS OF ENGINEERS... Ocean off Cape May, N.J.; Coast Guard Rifle Range. (a) The danger zone. The waters of the Atlantic Ocean...

33 CFR 334.100 - Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range. 334.100 Section 334.100 Navigation and Navigable Waters CORPS OF ENGINEERS... Ocean off Cape May, N.J.; Coast Guard Rifle Range. (a) The danger zone. The waters of the Atlantic Ocean...

33 CFR 334.100 - Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range. 334.100 Section 334.100 Navigation and Navigable Waters CORPS OF ENGINEERS... Ocean off Cape May, N.J.; Coast Guard Rifle Range. (a) The danger zone. The waters of the Atlantic Ocean...

33 CFR 334.100 - Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range. 334.100 Section 334.100 Navigation and Navigable Waters CORPS OF ENGINEERS... Ocean off Cape May, N.J.; Coast Guard Rifle Range. (a) The danger zone. The waters of the Atlantic Ocean...

33 CFR 334.100 - Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range. 334.100 Section 334.100 Navigation and Navigable Waters CORPS OF ENGINEERS... Ocean off Cape May, N.J.; Coast Guard Rifle Range. (a) The danger zone. The waters of the Atlantic Ocean...

Biology and host range of the moth Digitivalva delaireae as one of two candidate agents for biological control of Cape-ivy

USDA-ARS?s Scientific Manuscript database

Cape-ivy (Delairea odorata, Asteraceae), native to coastal floodplains and mountains in eastern South Africa, is an invasive vine in coastal riparian, woodland and scrub habitats in California and southern Oregon, as well as mid-elevation regions on some of the Hawaiian Islands. Cape-ivy smothers na...

Pre-release efficacy assessment of the leaf-mining moth Digitivalva delaireae (Lepidoptera: Glyphipterigidae), a potential biological control agent for Cape-ivy, Delairea odorata (Asteraceae), in western North America

USDA-ARS?s Scientific Manuscript database

The leaf-mining moth Digitivalva delaireae Gaedike & Kruger (Lepidoptera: Glyphipterigidae) is a potential biological control agent for the invasive vine Cape-ivy, Delairea odorata Lemaire (Asteraceae), in western North America, where two morphological varieties (stipulate and exstipulate) of Cape-i...

33 CFR 334.20 - Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. 334.20 Section 334.20 Navigation and Navigable Waters... REGULATIONS § 334.20 Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. (a) The...

33 CFR 334.20 - Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. 334.20 Section 334.20 Navigation and Navigable Waters... REGULATIONS § 334.20 Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. (a) The...

33 CFR 334.20 - Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. 334.20 Section 334.20 Navigation and Navigable Waters... REGULATIONS § 334.20 Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. (a) The...

33 CFR 334.20 - Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. 334.20 Section 334.20 Navigation and Navigable Waters... REGULATIONS § 334.20 Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. (a) The...

33 CFR 334.20 - Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. 334.20 Section 334.20 Navigation and Navigable Waters... REGULATIONS § 334.20 Gulf of Maine off Cape Small, Maine; naval aircraft practice mining range area. (a) The...

33 CFR 207.610 - St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and navigation of the harbor...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and navigation of the harbor and U.S. breakwater. 207.610 Section 207... NAVIGATION REGULATIONS § 207.610 St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and...

75 FR 65046 - In the Matter of Cape Systems Group, Inc., Caribbean Cigar Company, Casual Male Corp., Cell Power...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-21

... SECURITIES AND EXCHANGE COMMISSION In the Matter of Cape Systems Group, Inc., Caribbean Cigar...., File No. 500-1; Order of Suspension of Trading October 19, 2010. It appears to the Securities and... Cape Systems Group, Inc. because it has not filed any periodic reports since the period ended December...

46 CFR 7.150 - Canadian (BC) and United States (AK) Borders to Cape Spencer, AK.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Canadian (BC) and United States (AK) Borders to Cape Spencer, AK. 7.150 Section 7.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.150 Canadian (BC) and United States (AK) Borders to Cape...

46 CFR 7.150 - Canadian (BC) and United States (AK) Borders to Cape Spencer, AK.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Canadian (BC) and United States (AK) Borders to Cape Spencer, AK. 7.150 Section 7.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.150 Canadian (BC) and United States (AK) Borders to Cape...

46 CFR 7.150 - Canadian (BC) and United States (AK) Borders to Cape Spencer, AK.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Canadian (BC) and United States (AK) Borders to Cape Spencer, AK. 7.150 Section 7.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.150 Canadian (BC) and United States (AK) Borders to Cape...

46 CFR 7.150 - Canadian (BC) and United States (AK) Borders to Cape Spencer, AK.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Canadian (BC) and United States (AK) Borders to Cape Spencer, AK. 7.150 Section 7.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.150 Canadian (BC) and United States (AK) Borders to Cape...

46 CFR 7.150 - Canadian (BC) and United States (AK) Borders to Cape Spencer, AK.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Canadian (BC) and United States (AK) Borders to Cape Spencer, AK. 7.150 Section 7.150 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC BOUNDARY LINES Alaska § 7.150 Canadian (BC) and United States (AK) Borders to Cape...

50 CFR 648.81 - NE multispecies closed areas and measures to protect EFH.

Code of Federal Regulations, 2012 CFR

2012-10-01

... designed and used to take surfclams or ocean quahogs, provided that there is no retention of regulated...′ 70°00′ 1 Cape Cod shoreline on the Atlantic Ocean. (ii) Rolling Closure Area II. From April 1 through... Cape Cod Bay. 3 Cape Cod shoreline on the Atlantic Ocean. 4 New Hampshire shoreline. (iii) Rolling...

50 CFR 648.81 - NE multispecies closed areas and measures to protect EFH.

Code of Federal Regulations, 2014 CFR

2014-10-01

... designed and used to take surfclams or ocean quahogs, provided that there is no retention of regulated...′ 70°00′ 1 Cape Cod shoreline on the Atlantic Ocean. (ii) Rolling Closure Area II. From April 1 through... Cape Cod Bay. 3 Cape Cod shoreline on the Atlantic Ocean. 4 New Hampshire shoreline. (iii) Rolling...

50 CFR 648.81 - NE multispecies closed areas and measures to protect EFH.

Code of Federal Regulations, 2013 CFR

2013-10-01

... designed and used to take surfclams or ocean quahogs, provided that there is no retention of regulated...′ 70°00′ 1 Cape Cod shoreline on the Atlantic Ocean. (ii) Rolling Closure Area II. From April 1 through... Cape Cod Bay. 3 Cape Cod shoreline on the Atlantic Ocean. 4 New Hampshire shoreline. (iii) Rolling...

Cape of Storms or Cape of Good Hope? Educational Technology in a Changing Environment

ERIC Educational Resources Information Center

Czerniewicz, Laura

2004-01-01

This article locates and describes the work of the Multimedia Education Group (MEG) at the University of Cape Town (UCT). This work is contextualised by three national and international challenges, these being (1) the need to increase access to new technologies and overcome the digital divide, (2) the need to respond to a new communication order,…

46 CFR 7.60 - Cape Fear, NC to Sullivans Island, SC.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Cape Fear, NC to Sullivans Island, SC. 7.60 Section 7.60... Atlantic Coast § 7.60 Cape Fear, NC to Sullivans Island, SC. (a) A line drawn from the southernmost... Buoy “2CF”); thence to Oak Island Light. (b) A line drawn from the southernmost extremity of Bird...