9 CFR 319.500 - Meat pies.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Meat Food Entree Products, Pies, and Turnovers § 319.500 Meat pies. Meat pies such as “Beef Pie,” “Veal Pie,” and “Pork Pie” shall contain meat...

9 CFR 319.500 - Meat pies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Meat Food Entree Products, Pies, and Turnovers § 319.500 Meat pies. Meat pies such as “Beef Pie,” “Veal Pie,” and “Pork Pie” shall contain meat...

9 CFR 319.500 - Meat pies.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Meat Food Entree Products, Pies, and Turnovers § 319.500 Meat pies. Meat pies such as “Beef Pie,” “Veal Pie,” and “Pork Pie” shall contain meat...

9 CFR 319.500 - Meat pies.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Meat Food Entree Products, Pies, and Turnovers § 319.500 Meat pies. Meat pies such as “Beef Pie,” “Veal Pie,” and “Pork Pie” shall contain meat...

Vibrational autoionization of state-selective jet-cooled methanethiol (CH 3SH) investigated with infrared + vacuum-ultraviolet photoionization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Min; Shen, Zhitao; Pratt, S. T.

Vibrational autoionization of Rydberg states provides key information about nonadiabatic processes above an ionization threshold. In this work, we employed time-of-flight mass detection of CH 3SH + to record vibrational-state selective photo-ionization efficiency (PIE) spectra of jet-cooled methanethiol (CH 3SH) on exciting CH 3SH to a specific vibrationally excited state with an infrared (IR) laser, followed by excitation with a tunable laser in the vacuum-ultraviolet (VUV) region for ionization. Autoionizing Rydberg states assigned to the ns, np, nd and nf series are identified. When IR light at 2601 (ν 3, SH stretching mode) and 2948 cm -1 (ν 2, CHmore » 3 symmetric stretching mode) was employed, the Rydberg series converged to the respective vibrationally excited (ν 3 and ν 2) states of CH 3SH +. When IR light at 3014 cm -1 (overlapped ν 1/ν 9, CH 3 antisymmetric stretching and CH 2 antisymmetric stretching modes) was employed, Rydberg series converging to two vibrationally excited states (ν 1 and ν 9) of CH 3SH + were observed. When IR light at 2867 cm -1 (2ν 10, overtone of CH 3 deformation mode) and 2892 cm -1 (2ν 4, overtone of CH 2 scissoring mode) was employed, both Δν = -1 and Δν = -2 ionization transitions were observed; there is evidence for direct ionization from the initial state into the CH 3SH + (ν 4 + = 1) continuum. In all observed IR-VUV-PIE spectra, the ns and nd series show intensity greater than the other Rydberg series, which is consistent with the fact that the highest-occupied molecular orbital of CH 3SH is a p-like lone pair orbital on the S atom. Finally, the quantum yields for autoionization of various vibrational excited states are discussed. Values of ν 1 = 3035, ν 2 = 2884, ν 3 = 2514, and ν 9 = 2936 cm -1 for CH 3SH + derived from the converged limits agree satisfactorily with values observed for Ar-tagged CH 3SH + at 3026, 2879, 2502, and 2933 cm -1.« less

Vibrational autoionization of state-selective jet-cooled methanethiol (CH 3SH) investigated with infrared + vacuum-ultraviolet photoionization

DOE PAGES

Xie, Min; Shen, Zhitao; Pratt, S. T.; ...

2017-10-24

Vibrational autoionization of Rydberg states provides key information about nonadiabatic processes above an ionization threshold. In this work, we employed time-of-flight mass detection of CH 3SH + to record vibrational-state selective photo-ionization efficiency (PIE) spectra of jet-cooled methanethiol (CH 3SH) on exciting CH 3SH to a specific vibrationally excited state with an infrared (IR) laser, followed by excitation with a tunable laser in the vacuum-ultraviolet (VUV) region for ionization. Autoionizing Rydberg states assigned to the ns, np, nd and nf series are identified. When IR light at 2601 (ν 3, SH stretching mode) and 2948 cm -1 (ν 2, CHmore » 3 symmetric stretching mode) was employed, the Rydberg series converged to the respective vibrationally excited (ν 3 and ν 2) states of CH 3SH +. When IR light at 3014 cm -1 (overlapped ν 1/ν 9, CH 3 antisymmetric stretching and CH 2 antisymmetric stretching modes) was employed, Rydberg series converging to two vibrationally excited states (ν 1 and ν 9) of CH 3SH + were observed. When IR light at 2867 cm -1 (2ν 10, overtone of CH 3 deformation mode) and 2892 cm -1 (2ν 4, overtone of CH 2 scissoring mode) was employed, both Δν = -1 and Δν = -2 ionization transitions were observed; there is evidence for direct ionization from the initial state into the CH 3SH + (ν 4 + = 1) continuum. In all observed IR-VUV-PIE spectra, the ns and nd series show intensity greater than the other Rydberg series, which is consistent with the fact that the highest-occupied molecular orbital of CH 3SH is a p-like lone pair orbital on the S atom. Finally, the quantum yields for autoionization of various vibrational excited states are discussed. Values of ν 1 = 3035, ν 2 = 2884, ν 3 = 2514, and ν 9 = 2936 cm -1 for CH 3SH + derived from the converged limits agree satisfactorily with values observed for Ar-tagged CH 3SH + at 3026, 2879, 2502, and 2933 cm -1.« less

Type utilization of baked-smashed sweet potato and vegetables on patisserie product

NASA Astrophysics Data System (ADS)

Ana; Subekti, S.; Sudewi; Perdani, E. N.; Hanum, F.; Suciani, T.; Tania, V.

2016-04-01

The research was an experimental study in Green Skill Patisserie Course using Project-Based Learning model. It aims to complete the project development of pie named guramnis rainbow pie. Several experiments were carried out to produce a pie dough crust mixed with baked-smashed sweet potato and added with vegetables extract as the food coloring. The experiment method in order to make a better appearance or an attractive shape and to have more nutrition. In addition, the pie was filled with a mixture of sweet and sour gurame as Indonesian traditional food. By applying an organoleptic test to 10 respondents, the result shows that pie dough recipe using flour substituted by baked-smashed sweet potato with 2:1 of a ratio. Coloring pie dough adding extract vegetables (carrots, beets and celery) as color. We found that pie dough has more interesting pie color (90%) and the texture of the pie with a quite level of crispness (60%). Moreover, the pie taste is fairly (70%) and tasty (70%). Nutritional analysis results show that per size, serving guramnis rainbow pie contains energy as much as 81.72 calories, carbohydrates 12.5 grams, fat 2.32 grams and 2.77 grams of protein. The main findings are the pie appearance and taste was different compared to the previous pies because of the pie was served with gurame asam manis as the filling and had flour and cilembu sweet potato as the basic ingredients. The color of guramnis rainbow pie was resulted not only from food coloring but also from vegetables extract namely carrot (orange), bit (red), and salary (green). Thus, it had many benefits for health and adds the nutrition. The researchers recommend a further study in order to make pie dough with baked sweet potato and vegetables extract having an optimal level of crispness.

Utilization of Baked-Smashed Sweet Potato and Vegetables on Patisserie Product

NASA Astrophysics Data System (ADS)

Ana, A.; Subekti, S.; Sudewi, S.; Perdani, E. N.; Hanum, F.; Suciani, T.; Tania, V.

2018-02-01

The research was an experimental study in Green Skill Patisserie Course using Project-Based Learning model. It aims to complete the project development of pie named guramnis rainbow pie. Several experiments were carried out to produce a pie dough crust mixed with baked-smashed sweet potato and added with vegetables extract as the food coloring. The experiment method in order to make a better appearance or an attractive shape and to have more nutrition. In addition, the pie was filled with a mixture of sweet and sour gurame as Indonesian traditional food. By applying an organoleptic test to 10 respondents, the result shows that pie dough recipe using flour substituted by baked-smashed sweet potato with 2:1 of a ratio. Coloring pie dough adding extract vegetables (carrots, beets and celery) as color. We found that pie dough has more interesting pie color (90%) and the texture of the pie with a quite level of crispness (60%). Moreover, the pie taste is fairly (70%) and tasty (70%). Nutritional analysis results show that per size, serving guramnis rainbow pie contains energy as much as 81.72 calories, carbohydrates 12.5 grams, fat 2.32 grams and 2.77 grams of protein. The main findings are the pie appearance and taste was different compared to the previous pies because of the pie was served with gurame asam manis as the filling and had flour and cilembu sweet potato as the basic ingredients. The color of guramnis rainbow pie was resulted not only from food coloring but also from vegetables extract namely carrot (orange), bit (red), and salary (green). Thus, it had many benefits for health and adds the nutrition. The researchers recommend a further study in order to make pie dough with baked sweet potato and vegetables extract having an optimal level of crispness.

Coalition readiness management system preliminary interoperability experiment (CReaMS PIE)

NASA Astrophysics Data System (ADS)

Clark, Peter; Ryan, Peter; Zalcman, Lucien; Robbie, Andrew

2003-09-01

The United States Navy (USN) has initiated the Coalition Readiness Management System (CReaMS) Initiative to enhance coalition warfighting readiness through advancing development of a team interoperability training and combined mission rehearsal capability. It integrates evolving cognitive team learning principles and processes with advanced technology innovations to produce an effective and efficient team learning environment. The JOint Air Navy Networking Environment (JOANNE) forms the Australian component of CReaMS. The ultimate goal is to link Australian Defence simulation systems with the USN Battle Force Tactical Training (BFTT) system to demonstrate and achieve coalition level warfare training in a synthetic battlespace. This paper discusses the initial Preliminary Interoperability Experiment (PIE) involving USN and Australian Defence establishments.

Detection of rhodopsin dimerization in situ by PIE-FCCS, a time-resolved fluorescence spectroscopy.

PubMed

Smith, Adam W

2015-01-01

Rhodopsin self-associates in the plasma membrane. At low concentrations, the interactions are consistent with a monomer-dimer equilibrium (Comar et al., J Am Chem Soc 136(23):8342-8349, 2014). At high concentrations in native tissue, higher-order clusters have been observed (Fotiadis et al., Nature 421:127-128, 2003). The physiological role of rhodopsin dimerization is still being investigated, but it is clear that a quantitative assessment is essential to determining the function of rhodopsin clusters in vision. To quantify rhodopsin interactions, I will outline the theory and methodology of a specialized time-resolved fluorescence spectroscopy for measuring membrane protein-protein interactions called pulsed-interleaved excitation fluorescence cross-correlation spectroscopy (PIE-FCCS). The strength of this technique is its ability to quantify rhodopsin interactions in situ (i.e., a live cell plasma membrane). There are two reasons for restricting the scope to live cell membranes. First, the compositional heterogeneity of the plasma membrane creates a complex milieu with thousands of lipid, protein, and carbohydrate species. This makes it difficult to infer quaternary interactions from detergent solubilized samples or construct a model phospholipid bilayer that recapitulates all of the interactions present in native membranes. Second, organizational structure and dynamics is a key feature of the plasma membrane, and fixation techniques like formaldehyde cross-linking and vitrification will modulate the interactions. PIE-FCCS is based on two-color fluorescence imaging with time-correlated single-photon counting (TCSPC) (Becker et al., Rev Sci Instrum 70:1835-1841, 1999). By time-tagging every detected photon, the data can be analyzed as a fluorescence intensity distribution, fluorescence lifetime histogram, or fluorescence (cross-)correlation spectra (FCS/FCCS) (Becker, Advanced time-correlated single-photon counting techniques, Springer, Berlin, 2005). These analysis tools can then be used to quantify protein concentration, mobility, clustering, and Förster resonance energy transfer (FRET). In this paper I will focus on PIE-FCCS, which interleaves two wavelength excitation events in time so that the effects of spectral cross-talk and FRET can be isolated. In this way it is possible to characterize monomer-dimer-oligomer equilibria with high accuracy (Müller et al., Biophys J 89:3508-3522, 2005). Currently, PIE-FCCS requires a customized equipment configuration that will be described below. There is an excellent protocol that outlines traditional FCCS on a commercially available instrument (Bacia and Schwille, Nat Protoc 2:2842-2856, 2007). The PIE-FCCS approach is a relatively recent advance in FCCS that has been used in live cell assays to quantify lipid-anchored protein clustering (Triffo et al., J Am Chem Soc 134:10833-10842, 2012), epidermal growth factor receptor dimerization (Endres et al., Cell 152:543-556, 2013), and recently the dimerization of opsin (Comar et al., J Am Chem Soc 136(23):8342-8349, 2014). This paper will outline the theory and instrumentation requirements for PIE-FCCS, as well as the data collection and analysis process.

Pie waste - A component of food waste and a renewable substrate for producing ethanol.

PubMed

Magyar, Margaret; da Costa Sousa, Leonardo; Jayanthi, Singaram; Balan, Venkatesh

2017-04-01

Sugar-rich food waste is a sustainable feedstock that can be converted into ethanol without an expensive thermochemical pretreatment that is commonly used in first and second generation processes. In this manuscript we have outlined the pie waste conversion to ethanol through a two-step process, namely, enzyme hydrolysis using commercial enzyme products mixtures and microbial fermentation using yeast. Optimized enzyme cocktail was found to be 45% alpha amylase, 45% gamma amylase, and 10% pectinase at 2.5mg enzyme protein/g glucan produced a hydrolysate with high glucose concentration. All three solid loadings (20%, 30%, and 40%) produced sugar-rich hydrolysates and ethanol with little to no enzyme or yeast inhibition. Enzymatic hydrolysis and fermentation process mass balance was carried out using pie waste on a 1000g dry weight basis that produced 329g ethanol at 20% solids loading. This process clearly demonstrate how food waste could be efficiently converted to ethanol that could be used for making biodiesel by reacting with waste cooking oil. Copyright © 2017 Elsevier Ltd. All rights reserved.

Seasonal use of a New England estuary by foraging contingents of migratory striped bass

USGS Publications Warehouse

Mather, Martha E.; Pautzke, Sarah M.; Finn, John T.; Deegan, Linda A.; Muth, Robert M.

2011-01-01

Using acoustic telemetry on migratory striped bass Morone saxatilis in Plum Island Estuary (PIE), Massachusetts, we found that striped bass (335–634 mm total length) tagged in the spring and summer of 2005 (n = 14) and 2006 (n = 46) stayed in the estuary for an average of 66.0 d in 2005 and 72.2 d in 2006. Striped bass spent the most time in two specific reaches: middle Plum Island Sound and lower Rowley River. In both years, three different use-groups of striped bass were observed in PIE. Short-term visitors (n = 24) stayed in the estuary only briefly (range = 5–20 d). Two groups of seasonal residents stayed for more than 30 d, either in the Rowley River (n = 14) or in Plum Island Sound (n = 22). Within PIE, the two seasonal-resident use-groups may be foraging contingents that learn how to feed efficiently in specific parts of the estuary. These distinct within-estuary use patterns could have different implications for striped bass condition and prey impact.

The wheat ethylene response factor transcription factor pathogen-induced ERF1 mediates host responses to both the necrotrophic pathogen Rhizoctonia cerealis and freezing stresses.

PubMed

Zhu, Xiuliang; Qi, Lin; Liu, Xin; Cai, Shibin; Xu, Huijun; Huang, Rongfeng; Li, Jiarui; Wei, Xuening; Zhang, Zengyan

2014-03-01

Sharp eyespot disease (primarily caused by the pathogen Rhizoctonia cerealis) and freezing stress are important yield limitations for the production of wheat (Triticum aestivum). Here, we report new insights into the function and underlying mechanisms of an ethylene response factor (ERF) in wheat, Pathogen-Induced ERF1 (TaPIE1), in host responses to R. cerealis and freezing stresses. TaPIE1-overexpressing transgenic wheat exhibited significantly enhanced resistance to both R. cerealis and freezing stresses, whereas TaPIE1-underexpressing wheat plants were more susceptible to both stresses relative to control plants. Following both stress treatments, electrolyte leakage and hydrogen peroxide content were significantly reduced, and both proline and soluble sugar contents were elevated in TaPIE1-overexpressing wheat, whereas these physiological traits in TaPIE1-underexpressing wheat exhibited the opposite trend. Microarray and quantitative reverse transcription-polymerase chain reaction analyses of TaPIE1-overexpressing and -underexpressing wheat plants indicated that TaPIE1 activated a subset of defense- and stress-related genes. Assays of DNA binding by electrophoretic mobility shift and transient expression in tobacco (Nicotiana tabacum) showed that the GCC boxes in the promoters of TaPIE1-activated genes were essential for transactivation by TaPIE1. The transactivation activity of TaPIE1 and the expression of TaPIE1-activated defense- and stress-related genes were significantly elevated following R. cerealis, freezing, and exogenous ethylene treatments. TaPIE1-mediated responses to R. cerealis and freezing were positively modulated by ethylene biosynthesis. These data suggest that TaPIE1 positively regulates the defense responses to R. cerealis and freezing stresses by activating defense- and stress-related genes downstream of the ethylene signaling pathway and by modulating related physiological traits in wheat.

The Wheat Ethylene Response Factor Transcription Factor PATHOGEN-INDUCED ERF1 Mediates Host Responses to Both the Necrotrophic Pathogen Rhizoctonia cerealis and Freezing Stresses1[C][W][OPEN

PubMed Central

Zhu, Xiuliang; Qi, Lin; Liu, Xin; Cai, Shibin; Xu, Huijun; Huang, Rongfeng; Li, Jiarui; Wei, Xuening; Zhang, Zengyan

2014-01-01

Sharp eyespot disease (primarily caused by the pathogen Rhizoctonia cerealis) and freezing stress are important yield limitations for the production of wheat (Triticum aestivum). Here, we report new insights into the function and underlying mechanisms of an ethylene response factor (ERF) in wheat, Pathogen-Induced ERF1 (TaPIE1), in host responses to R. cerealis and freezing stresses. TaPIE1-overexpressing transgenic wheat exhibited significantly enhanced resistance to both R. cerealis and freezing stresses, whereas TaPIE1-underexpressing wheat plants were more susceptible to both stresses relative to control plants. Following both stress treatments, electrolyte leakage and hydrogen peroxide content were significantly reduced, and both proline and soluble sugar contents were elevated in TaPIE1-overexpressing wheat, whereas these physiological traits in TaPIE1-underexpressing wheat exhibited the opposite trend. Microarray and quantitative reverse transcription-polymerase chain reaction analyses of TaPIE1-overexpressing and -underexpressing wheat plants indicated that TaPIE1 activated a subset of defense- and stress-related genes. Assays of DNA binding by electrophoretic mobility shift and transient expression in tobacco (Nicotiana tabacum) showed that the GCC boxes in the promoters of TaPIE1-activated genes were essential for transactivation by TaPIE1. The transactivation activity of TaPIE1 and the expression of TaPIE1-activated defense- and stress-related genes were significantly elevated following R. cerealis, freezing, and exogenous ethylene treatments. TaPIE1-mediated responses to R. cerealis and freezing were positively modulated by ethylene biosynthesis. These data suggest that TaPIE1 positively regulates the defense responses to R. cerealis and freezing stresses by activating defense- and stress-related genes downstream of the ethylene signaling pathway and by modulating related physiological traits in wheat. PMID:24424323

Personalized Information Environments: Do Public Libraries Want a Slice of the PIE?

ERIC Educational Resources Information Center

Worcester, Lea

2003-01-01

Discussion of personalized information environments (PIEs) focuses on library personalized interfaces. Describes academic library PIEs and commercial sites, such as Amazon.com that use personalization; explores the Public Library of Charlotte and Mecklenburg's personalized interface; and discusses opportunities and challenges PIEs offer public…

Lea's Pies

NASA Technical Reports Server (NTRS)

1996-01-01

The Technology Transfer Office at Stennis Space Center worked with a pie company owner to develop an inexpensive container that would protect pies and keep them in a near frozen condition for shipping in 48 hours. A NASA engineer made a thermal barrier envelope from a metalized mylar called 'space blanket material,' developed during the Apollo era. The envelope protects the pies from heat transfer. Pictured, a NASA engineer removes the temperature logger from a pecan pie shipped to him in a prototype envelope.

Rethinking Reinforcement: Allocation, Induction, and Contingency

PubMed Central

Baum, William M

2012-01-01

The concept of reinforcement is at least incomplete and almost certainly incorrect. An alternative way of organizing our understanding of behavior may be built around three concepts: allocation, induction, and correlation. Allocation is the measure of behavior and captures the centrality of choice: All behavior entails choice and consists of choice. Allocation changes as a result of induction and correlation. The term induction covers phenomena such as adjunctive, interim, and terminal behavior—behavior induced in a situation by occurrence of food or another Phylogenetically Important Event (PIE) in that situation. Induction resembles stimulus control in that no one-to-one relation exists between induced behavior and the inducing event. If one allowed that some stimulus control were the result of phylogeny, then induction and stimulus control would be identical, and a PIE would resemble a discriminative stimulus. Much evidence supports the idea that a PIE induces all PIE-related activities. Research also supports the idea that stimuli correlated with PIEs become PIE-related conditional inducers. Contingencies create correlations between “operant” activity (e.g., lever pressing) and PIEs (e.g., food). Once an activity has become PIE-related, the PIE induces it along with other PIE-related activities. Contingencies also constrain possible performances. These constraints specify feedback functions, which explain phenomena such as the higher response rates on ratio schedules in comparison with interval schedules. Allocations that include a lot of operant activity are “selected” only in the sense that they generate more frequent occurrence of the PIE within the constraints of the situation; contingency and induction do the “selecting.” PMID:22287807

The PIE Institute Project: Final Evaluation Report

ERIC Educational Resources Information Center

St. John, Mark; Carroll, Becky; Helms, Jen; Smith, Anita

2008-01-01

The Playful Invention and Exploration (PIE) Institute project was funded in 2005 by the National Science Foundation (NSF). For the past three years, Inverness Research has served as the external evaluator for the PIE project. The authors' evaluation efforts have included extensive observation and documentation of PIE project activities; ongoing…

Frequency Width in Predictions of Windsea Spectra and the Role of the Nonlinear Solver

DTIC Science & Technology

2012-12-20

Space Center, MS 39529-5004 3. DATES COVERED IFrom - Taj 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 0601153N 5d...passes through the origin. 5. Pearson’s correlation coefficient (CC) as computed by, for exam- pie, Cardone et al. (1996), Ardhuin et al. (2010), cc...Wavetrains in inhomogeneous moving media. Proc. Royal Soc. London A 302, 529-554. Cardone . V.J., Jensen, R.E„ Resio, D.T.. Swail, V.R.. Cox. A.T., 1996

High mobility group box 1 in patients with 2009 pandemic H1N1 influenza-associated encephalopathy.

PubMed

Momonaka, Hiroshi; Hasegawa, Shunji; Matsushige, Takeshi; Inoue, Hirofumi; Kajimoto, Madoka; Okada, Seigo; Nakatsuka, Kenji; Morishima, Tsuneo; Ichiyama, Takashi

2014-06-01

Patients with 2009 pandemic H1N1 influenza-associated encephalopathy (pIE) have been reported in Japan. The most common clinical symptoms of this condition are seizures and progressive coma with high-grade fever. We previously highlighted the cytokine profile of pIE; our results suggest that proinflammatory cytokines play an important role in the pathogenesis. High mobility group box 1 (HMGB1) protein is a late mediator of inflammation or sepsis. However, there are few reports regarding the serum and cerebrospinal fluid (CSF) levels of HMGB1 in pIE patients. We measured serum and CSF levels of HMGB1 in the following: pIE patients with poor outcomes, pIE patients without neurological sequelae, influenza patients without pIE, and control subjects. Serum HMGB1 levels were significantly higher in pIE patients with poor outcomes compared to those without neurological sequelae. In contrast, there was no difference in CSF HMGB1 levels among all groups. Regarding pIE patients, we found a significant positive correlation between HMGB1 levels and IL-6 in the serum but not in the CSF. Our results suggest that HMGB1 protein may be involved in the pathogenesis of pIE and that a high serum, but not CSF, level of inflammatory cytokines plays an important role in the severity of pIE. Copyright © 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

Post irradiation effects (PIE) in integrated circuits

NASA Technical Reports Server (NTRS)

Shaw, D. C.; Lowry, L.; Barnes, C.; Zakharia, M.; Agarwal, S.; Rax, B.

1991-01-01

Post-irradiation effects (PIE) ranging from normal recovery to catastrophic failure have been observed in integrated circuits during the PIE period. Data presented show failure due to rebound after a 10 krad(Si) dose. In particular, five device types are investigated with varying PIE response. Special attention has been given to the HI1-507A analog multiplexer because its PIE response is extreme. X-ray diffraction has been uniquely employed to measure physical stress in the HI1-507A metallization. An attempt has been made to show a relationship between stress relaxation and radiation effects. All data presented support the current MIL-STD Method 1019.4 but demonstrate the importance of performing PIE measurements, even when mission doses are as low as 10 krad(Si).

How a New Health Intervention Affects the Health Systems? Learnings from Pentavalent Vaccine Introduction in India.

PubMed

Lahariya, Chandrakant; Paruthi, Renu; Bhattacharya, Madhulekha

2016-04-01

To summarize the findings from a Post Introduction Evaluation (PIE) of pentavalent vaccine in Tamil Nadu and Kerala state of India and to understand how the health systems could be prepared for (prior to) introducing a new intervention and how such introduction could affect the health systems (afterwards). A post introduction evaluation (PIE) of Haemophilus influenzae type b (Hib) as pentavalent (DPT + HepB + Hib) vaccine was conducted in Tamil Nadu and Kerala states of India in July-Aug 2012. The PIE was conducted as per World Health Organization PIE methods and tools specifically adapted for India. This PIE adopted a 'mixed method approach' with qualitative data focus. The planning for the introduction of pentavalent vaccine provided opportunities to strengthen various functions of the health system i.e., piloting of Open Vial Policy, strengthening surveillance system, improving Adverse Events Following Immunization (AEFI) reporting system and formation of the technical expert groups. It provided opportunity for bringing attention on the immunization programme in general as well. After the vaccine introduction, the beneficial effects were noted on stewardship (increased oversight by top level policy makers and programme managers), creating resources (investment and trainings of staff in immunization), service delivery (increased coverage with the vaccines and improved quality of services) and financing (increased financial allocation and reduced out of pocket expenditures as more people started attending public health facilities). The vaccine introduction was found to be associated with improvement in the health equity, efficiency and service utilization (effective coverage). New vaccine introduction provides opportunities (both before and after) for strengthening the health systems in setting such as India. Preparing the health system for new challenges has potential to strengthen the health systems, if done in well-coordinated and planned manner. Considering that essential steps are largely similar, these lessons could be applicable for the introduction of other new health interventions in the similar settings.

49 CFR 40.363 - On what basis may the Department issue a PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false On what basis may the Department issue a PIE? 40... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.363 On what basis may the Department issue a PIE? (a) If you are a service agent, the Department may issue a PIE concerning...

49 CFR 40.377 - Who decides whether to issue a PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.377 Who decides whether to issue a PIE? (a) The ODAPC Director, or his or her designee, decides whether to issue a PIE. If a designee... 49 Transportation 1 2010-10-01 2010-10-01 false Who decides whether to issue a PIE? 40.377 Section...

49 CFR 40.385 - Who bears the burden of proof in a PIE proceeding?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Who bears the burden of proof in a PIE proceeding... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.385 Who bears the burden of proof in a PIE proceeding? (a) As the proponent of issuing a PIE, the initiating official bears...

A nickel-foam@carbon-shell with a pie-like architecture as an efficient polysulfide trap for high-energy Li–S batteries

DOE PAGES

Luo, Liu; Chung, Sheng-Heng; Chang, Chi-Hao; ...

2017-07-06

A high-loading sulfur cathode is critical for establishing rechargeable lithium–sulfur (Li–S) batteries with the anticipated high energy density. However, its fabrication as well as realizing high electrochemical utilization and stability with high-loading sulfur cathodes is a daunting challenge. Here, we present a new pie-like electrode that consists of an electrocatalytic nickel-foam as a “filling” to adsorb and store polysulfide catholytes and an outer carbon shell as a “crust” for facilitating high-loading sulfur cathodes with superior electrochemical and structural stabilities. The inner electrocatalytic nickel-foam is configured to adsorb polysulfides and facilitate their redox reactions. The intertwined carbon shell assists to shieldmore » the polysulfides within the cathode region of the cell. Both the nickel-foam and the carbon shell have high conductivity and porous space, which serve simultaneously as interconnected current collectors to enhance the redox kinetics and as polysulfide reservoirs to confine the active material. The effectiveness of such a pie-like structure in improving the electrochemical efficiency enables the cathode to host an ultrahigh sulfur loading of 40 mg cm -2 and attain a high areal capacity of over 40 mA h cm -2 at a low electrolyte/sulfur (E/S) ratio of 7. The enhanced cyclability is reflected in a high reversible areal capacity approaching 30 mA h cm -2 at C/5 rate after 100 cycles and excellent rate capability up to 2C rate.« less

A nickel-foam@carbon-shell with a pie-like architecture as an efficient polysulfide trap for high-energy Li–S batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luo, Liu; Chung, Sheng-Heng; Chang, Chi-Hao

A high-loading sulfur cathode is critical for establishing rechargeable lithium–sulfur (Li–S) batteries with the anticipated high energy density. However, its fabrication as well as realizing high electrochemical utilization and stability with high-loading sulfur cathodes is a daunting challenge. Here, we present a new pie-like electrode that consists of an electrocatalytic nickel-foam as a “filling” to adsorb and store polysulfide catholytes and an outer carbon shell as a “crust” for facilitating high-loading sulfur cathodes with superior electrochemical and structural stabilities. The inner electrocatalytic nickel-foam is configured to adsorb polysulfides and facilitate their redox reactions. The intertwined carbon shell assists to shieldmore » the polysulfides within the cathode region of the cell. Both the nickel-foam and the carbon shell have high conductivity and porous space, which serve simultaneously as interconnected current collectors to enhance the redox kinetics and as polysulfide reservoirs to confine the active material. The effectiveness of such a pie-like structure in improving the electrochemical efficiency enables the cathode to host an ultrahigh sulfur loading of 40 mg cm -2 and attain a high areal capacity of over 40 mA h cm -2 at a low electrolyte/sulfur (E/S) ratio of 7. The enhanced cyclability is reflected in a high reversible areal capacity approaching 30 mA h cm -2 at C/5 rate after 100 cycles and excellent rate capability up to 2C rate.« less

The causal pie model: an epidemiological method applied to evolutionary biology and ecology.

PubMed

Wensink, Maarten; Westendorp, Rudi G J; Baudisch, Annette

2014-05-01

A general concept for thinking about causality facilitates swift comprehension of results, and the vocabulary that belongs to the concept is instrumental in cross-disciplinary communication. The causal pie model has fulfilled this role in epidemiology and could be of similar value in evolutionary biology and ecology. In the causal pie model, outcomes result from sufficient causes. Each sufficient cause is made up of a "causal pie" of "component causes". Several different causal pies may exist for the same outcome. If and only if all component causes of a sufficient cause are present, that is, a causal pie is complete, does the outcome occur. The effect of a component cause hence depends on the presence of the other component causes that constitute some causal pie. Because all component causes are equally and fully causative for the outcome, the sum of causes for some outcome exceeds 100%. The causal pie model provides a way of thinking that maps into a number of recurrent themes in evolutionary biology and ecology: It charts when component causes have an effect and are subject to natural selection, and how component causes affect selection on other component causes; which partitions of outcomes with respect to causes are feasible and useful; and how to view the composition of a(n apparently homogeneous) population. The diversity of specific results that is directly understood from the causal pie model is a test for both the validity and the applicability of the model. The causal pie model provides a common language in which results across disciplines can be communicated and serves as a template along which future causal analyses can be made.

Wax inhibitor based on ethylene vinyl acetate with methyl methacrylate and diethanolamine for crude oil pipeline

NASA Astrophysics Data System (ADS)

Anisuzzaman, S. M.; Abang, S.; Bono, A.; Krishnaiah, D.; Karali, R.; Safuan, M. K.

2017-06-01

Wax precipitation and deposition is one of the most significant flow assurance challenges in the production system of the crude oil. Wax inhibitors are developed as a preventive strategy to avoid an absolute wax deposition. Wax inhibitors are polymers which can be known as pour point depressants as they impede the wax crystals formation, growth, and deposition. In this study three formulations of wax inhibitors were prepared, ethylene vinyl acetate, ethylene vinyl acetate co-methyl methacrylate (EVA co-MMA) and ethylene vinyl acetate co-diethanolamine (EVA co-DEA) and the comparison of their efficiencies in terms of cloud point¸ pour point, performance inhibition efficiency (%PIE) and viscosity were evaluated. The cloud point and pour point for both EVA and EVA co-MMA were similar, 15°C and 10-5°C, respectively. Whereas, the cloud point and pour point for EVA co-DEA were better, 10°C and 10-5°C respectively. In conclusion, EVA co-DEA had shown the best % PIE (28.42%) which indicates highest percentage reduction of wax deposit as compared to the other two inhibitors.

Estrogenicity of the isoflavone genistein pigeon pie seeds (Cajanus cajan L. Mill sp.) on reproductive organs in rat

NASA Astrophysics Data System (ADS)

Novi Primiani, Cicilia; Pujiati; Hardani

2018-05-01

Genistein is a compound with structures and properties similar to 17β estradiol which can be extracted from pigeon pie. The aim of the study was to identify the genistein profiles of pigeon pie in blood, urine, and feces and their effects on uterine and vaginal tissue structures of rats. Nine female white rats of Sprague Dawley, 6-7 months, weighing 150-180 g, were used and given pigeon pie seed solution for 36 days, genistein profiles were analyzed using HPLC, uterine and vaginal tissue structures were analyzed with HE staining. The results showed that the genistein contained in pigeon pie was lower than that in the synthetic genistein; vaginal epithelials and uterine proliferations were indicated. To conclude, pigeon pie was found to contain genistein which is a potential alternative for a natural estrogen source.

Objectives and Layout of a High-Resolution X-ray Imaging Crystal Spectrometer for the Large Helical Device (LHD)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bitter, M; Gates, D; Monticello, D

A high-resolution X-ray imaging crystal spectrometer, whose concept was tested on NSTX and Alcator C-Mod, is being designed for LHD. This instrument will record spatially resolved spectra of helium-like Ar16+ and provide ion temperature profiles with spatial and temporal resolutions of < 2 cm and ≥ 10 ms. The stellarator equilibrium reconstruction codes, STELLOPT and PIES, will be used for the tomographic inversion of the spectral data. The spectrometer layout and instrumental features are largely determined by the magnetic field structure of LHD.

Social suppliers: Exploring the cultural contours of the performance and image enhancing drug (PIED) market among bodybuilders in the Netherlands and Belgium.

PubMed

van de Ven, Katinka; Mulrooney, Kyle J D

2017-02-01

This paper explores the understudied phenomenon of performance and image enhancing drug (PIED) markets by examining the structure and formation of the market for PIEDs among bodybuilders in the Netherlands and Belgium. This article specifically seeks to account for individual reasons and motivations for dealing PIEDs within these bodybuilding subcultures. Understanding illicit PIED markets is important for policy decisions as knowledge on the production and distribution of these substances may assist in designing law enforcement efforts, harm reduction initiatives and treatment options. This article draws on two years of fieldwork in various bodybuilding settings, 47 semi-structured interviews with individuals who are directly or indirectly involved in the PIED market and 64 PIED dealing cases initiated by criminal justice agencies in the Netherlands and Belgium. The data indicates that PIED dealing groups and individuals are often driven by motivations stemming from their social and cultural embeddedness in the bodybuilding subculture. Specifically, these PIED dealers are 'over-socialized' into the structure and culture of bodybuilding and follow the cultural scripts that come with their group affiliation and organization. As a result of the cultural context in which these transactions occur, PIED dealing networks among bodybuilders in the Netherlands and Belgium are more likely to consist of friends or 'friends of friends' tied together by threads of collective meaning found within the bodybuilding subculture. We argue that efforts seeking to explain the structure, formation and motivations of illicit PIED dealing must learn to appreciate how culture mediates structural forces and thereby influences individual and collective action. Policy makers, health care professionals and other relevant parties should consider a plurality of factors (social, economic and cultural) when designing and evaluating PIED-related interventions such as law enforcement efforts, harm reduction initiatives and treatment options. Copyright © 2016 Elsevier B.V. All rights reserved.

The relationship of family characteristics and bipolar disorder using causal-pie models.

PubMed

Chen, Y-C; Kao, C-F; Lu, M-K; Yang, Y-K; Liao, S-C; Jang, F-L; Chen, W J; Lu, R-B; Kuo, P-H

2014-01-01

Many family characteristics were reported to increase the risk of bipolar disorder (BPD). The development of BPD may be mediated through different pathways, involving diverse risk factor profiles. We evaluated the associations of family characteristics to build influential causal-pie models to estimate their contributions on the risk of developing BPD at the population level. We recruited 329 clinically diagnosed BPD patients and 202 healthy controls to collect information in parental psychopathology, parent-child relationship, and conflict within family. Other than logistic regression models, we applied causal-pie models to identify pathways involved with different family factors for BPD. The risk of BPD was significantly increased with parental depression, neurosis, anxiety, paternal substance use problems, and poor relationship with parents. Having a depressed mother further predicted early onset of BPD. Additionally, a greater risk for BPD was observed with higher numbers of paternal/maternal psychopathologies. Three significant risk profiles were identified for BPD, including paternal substance use problems (73.0%), maternal depression (17.6%), and through poor relationship with parents and conflict within the family (6.3%). Our findings demonstrate that different aspects of family characteristics elicit negative impacts on bipolar illness, which can be utilized to target specific factors to design and employ efficient intervention programs. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

49 CFR 40.387 - What matters does the Director decide concerning a proposed PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.387 What matters does...) Whether the facts support issuing a PIE; (3) The scope of any PIE that is issued; and (4) The duration of...

Reduction Osteotomy vs Pie-Crust Technique as Possible Alternatives for Medial Release in Total Knee Arthroplasty and Compared in a Prospective Randomized Controlled Trial.

PubMed

Ahn, Ji Hyun; Yang, Tae Yeong; Lee, Jang Yun

2016-07-01

To compare the gap change between the pie-crust technique and reduction osteotomy to determine their effects on flexion and extension gaps and their success rates in achieving ligament balancing during total knee arthroplasty. In a prospective randomized controlled trial, 106 total knee arthroplasties were allocated to each group with 53 cases. If there was a narrow medial gap with an imbalance of ≥3 mm after the initial limited medial release, either reduction osteotomy or pie-crust technique was performed. The changes of extension and flexion medial gaps along with the success rate of mediolateral balancing were compared. There was a significant difference in the change of medial gap in knee extension with mean changes of 3.5 ± 0.5 mm and 2.3 ± 0.8 mm in the reduction osteotomy and pie-crust groups, respectively (P < .001). For flexion gap, greater change was found in the pie-crust group compared with the reduction osteotomy group; the mean medial gap changes in knee flexion were 1.1 ± 0.5 mm and 2.3 ± 1.2 mm in the reduction osteotomy and pie-crust groups, respectively. The success rates were 90.6% and 67.9% in reduction osteotomy and pie-crust groups, respectively (P = .007). As an alternative medial release method, reduction osteotomy was more effective in extension gap balancing, and pie-crust technique was more effective in flexion gap balancing. The overall success rate of mediolateral ligament balancing was higher in the reduction osteotomy group than in the pie-crust group. Copyright © 2016 Elsevier Inc. All rights reserved.

The causal pie model: an epidemiological method applied to evolutionary biology and ecology

PubMed Central

Wensink, Maarten; Westendorp, Rudi G J; Baudisch, Annette

2014-01-01

A general concept for thinking about causality facilitates swift comprehension of results, and the vocabulary that belongs to the concept is instrumental in cross-disciplinary communication. The causal pie model has fulfilled this role in epidemiology and could be of similar value in evolutionary biology and ecology. In the causal pie model, outcomes result from sufficient causes. Each sufficient cause is made up of a “causal pie” of “component causes”. Several different causal pies may exist for the same outcome. If and only if all component causes of a sufficient cause are present, that is, a causal pie is complete, does the outcome occur. The effect of a component cause hence depends on the presence of the other component causes that constitute some causal pie. Because all component causes are equally and fully causative for the outcome, the sum of causes for some outcome exceeds 100%. The causal pie model provides a way of thinking that maps into a number of recurrent themes in evolutionary biology and ecology: It charts when component causes have an effect and are subject to natural selection, and how component causes affect selection on other component causes; which partitions of outcomes with respect to causes are feasible and useful; and how to view the composition of a(n apparently homogeneous) population. The diversity of specific results that is directly understood from the causal pie model is a test for both the validity and the applicability of the model. The causal pie model provides a common language in which results across disciplines can be communicated and serves as a template along which future causal analyses can be made. PMID:24963386

Acceptability and preliminary feasibility of an internet/CD-ROM-based education and decision program for early-stage prostate cancer patients: randomized pilot study.

PubMed

Diefenbach, Michael A; Mohamed, Nihal E; Butz, Brian P; Bar-Chama, Natan; Stock, Richard; Cesaretti, Jamie; Hassan, Waleed; Samadi, David; Hall, Simon J

2012-01-13

Prostate cancer is the most common cancer affecting men in the United States. Management options for localized disease exist, yet an evidence-based criterion standard for treatment still has to emerge. Although 5-year survival rates approach 98%, all treatment options carry the possibility for significant side effects, such as erectile dysfunction and urinary incontinence. It is therefore recommended that patients be actively involved in the treatment decision process. We have developed an Internet/CD-ROM-based multimedia Prostate Interactive Educational System (PIES) to enhance patients' treatment decision making. PIES virtually mirrors a health center to provide patients with information about prostate cancer and its treatment through an intuitive interface, using videos, animations, graphics, and texts. (1) To examine the acceptability and feasibility of the PIES intervention and to report preliminary outcomes of the program in a pilot trial among patients with a new prostate cancer diagnosis, and (2) to explore the potential impact of tailoring PIES treatment information to participants' information-seeking styles on study outcomes. Participants (n = 72) were patients with newly diagnosed localized prostate cancer who had not made a treatment decision. Patients were randomly assigned to 3 experimental conditions: (1) control condition (providing information through standard National Cancer Institute brochures; 26%), and PIES (2) with tailoring (43%) and (3) without tailoring to a patient's information-seeking style (31%). Questionnaires were administrated before (t1) and immediately after the intervention (t2). Measurements include evaluation and acceptability of the PIES intervention, monitoring/blunting information-seeking style, psychological distress, and decision-related variables (eg, decisional confidence, feeling informed about prostate cancer and treatment, and treatment preference). The PIES program was well accepted by patients and did not interfere with the clinical routine. About 79% of eligible patients (72/91) completed the pre- and post-PIES intervention assessments. Patients in the PIES groups compared with those in the control condition were significantly more likely to report higher levels of confidence in their treatment choices, higher levels of helpfulness of the information they received in making a treatment decision, and that the information they received was emotionally reassuring. Patients in the PIES groups compared with those in the control condition were significantly less likely to need more information about treatment options, were less anxious about their treatment choices, and thought the information they received was clear (P < .05). Tailoring PIES information to information-seeking style was not related to decision-making variables. This pilot study confirms that the implementation of PIES within a clinical practice is feasible and acceptable to patients with a recent diagnosis of prostate cancer. PIES improved key decision-making process variables and reduced the emotional impact of a difficult medical decision.

The genes Scgb1a1, Lpo and Gbp2 characteristically expressed in peri-implant epithelium of rats.

PubMed

Mori, Gentaro; Sasaki, Hodaka; Makabe, Yasushi; Yoshinari, Masao; Yajima, Yasutomo

2016-12-01

The peri-implant epithelium (PIE) plays an important role in the prevention against initial stage of inflammation. To minimize the risk of peri-implantitis, it is necessary to understand the biological characteristics of the PIE. The aim of this study was to investigate the characteristic gene expression profile of PIE as compared to junctional epithelium (JE) using laser microdissection and microarray analysis. Left upper first molars of 4-week-old rat were extracted, and titanium alloy implants were placed. Four weeks after surgery, samples were harvested by laser microdissection, and total RNA samples were isolated. Comprehensive analyses of genes expressed in the JE and PIE were performed using microarray analysis. Confirmation of the differential expression of selected genes was performed by quantitative real-time polymerase chain reaction and immunohistochemistry. The microarray analysis showed that 712 genes were more than twofold change upregulated in the PIE compared with the JE. Genes Scgb1a1 were significantly upregulated more than 19.1-fold, Lpo more than 19.0-fold, and Gbp2 more than 8.9-fold, in the PIE (P < 0.01). Immunohistochemical localization of SCGB1A1, LPO, and GBP2 was observed in PIE. The present results suggested that genes Scgb1a1, Lpo, and Gbp2 are characteristically expressed in the PIE. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

46 CFR 16.109 - Public Interest Exclusion (PIE).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Public Interest Exclusion (PIE). 16.109 Section 16.109 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN CHEMICAL TESTING General § 16.109 Public Interest Exclusion (PIE). Service agents are subject to Public Interest Exclusion...

Serum and cerebrospinal fluid cytokine profile of patients with 2009 pandemic H1N1 influenza virus-associated encephalopathy.

PubMed

Hasegawa, Shunji; Matsushige, Takeshi; Inoue, Hirofumi; Shirabe, Komei; Fukano, Reiji; Ichiyama, Takashi

2011-05-01

Since April 2009, the number of patients with 2009 pandemic H1N1 influenza virus infection has been increasing in Japan just as in the rest of the world. Patients with 2009 pandemic H1N1 influenza-associated encephalopathy (pIE) have also been reported. The common clinical symptoms of this condition are seizures and progressive coma with high-grade fever. We previously reported the possible association between seasonal influenza-associated encephalopathy (sIE) and proinflammatory cytokines. However, the pathogenesis of pIE remains to be elucidated. In pIE patients with a poor outcome, the serum levels of interleukin (IL)-6, IL-10, and soluble tumor necrosis factor (TNF) receptor (sTNFR1) were significantly higher than those in pIE patients without neurological sequelae. Similarly, the cerebrospinal fluid (CSF) IL-6 levels in pIE patients with a poor outcome were significantly higher than those in pIE patients without neurological sequelae. Our results suggest that IL-6, TNF-α, and IL-10 play important roles in pIE, and that the serum levels of IL-6, IL-10, and sTNFR1 and the CSF levels of IL-6 are related to neurological complications. Copyright © 2011 Elsevier Ltd. All rights reserved.

Efficient numerical calculation of MHD equilibria with magnetic islands, with particular application to saturated neoclassical tearing modes

NASA Astrophysics Data System (ADS)

Raburn, Daniel Louis

We have developed a preconditioned, globalized Jacobian-free Newton-Krylov (JFNK) solver for calculating equilibria with magnetic islands. The solver has been developed in conjunction with the Princeton Iterative Equilibrium Solver (PIES) and includes two notable enhancements over a traditional JFNK scheme: (1) globalization of the algorithm by a sophisticated backtracking scheme, which optimizes between the Newton and steepest-descent directions; and, (2) adaptive preconditioning, wherein information regarding the system Jacobian is reused between Newton iterations to form a preconditioner for our GMRES-like linear solver. We have developed a formulation for calculating saturated neoclassical tearing modes (NTMs) which accounts for the incomplete loss of a bootstrap current due to gradients of multiple physical quantities. We have applied the coupled PIES-JFNK solver to calculate saturated island widths on several shots from the Tokamak Fusion Test Reactor (TFTR) and have found reasonable agreement with experimental measurement.

Objectives and layout of a high-resolution x-ray imaging crystal spectrometer for the large helical device.

PubMed

Bitter, M; Hill, K; Gates, D; Monticello, D; Neilson, H; Reiman, A; Roquemore, A L; Morita, S; Goto, M; Yamada, H; Rice, J E

2010-10-01

A high-resolution x-ray imaging crystal spectrometer, whose concept was tested on NSTX and Alcator C-Mod, is being designed for the large helical device (LHD). This instrument will record spatially resolved spectra of helium-like Ar(16+) and will provide ion temperature profiles with spatial and temporal resolutions of <2 cm and ≥10 ms, respectively. The spectrometer layout and instrumental features are largely determined by the magnetic field structure of LHD. The stellarator equilibrium reconstruction codes, STELLOPT and PIES, will be used for the tomographic inversion of the spectral data.

Variable aperture-based ptychographical iterative engine method

NASA Astrophysics Data System (ADS)

Sun, Aihui; Kong, Yan; Meng, Xin; He, Xiaoliang; Du, Ruijun; Jiang, Zhilong; Liu, Fei; Xue, Liang; Wang, Shouyu; Liu, Cheng

2018-02-01

A variable aperture-based ptychographical iterative engine (vaPIE) is demonstrated both numerically and experimentally to reconstruct the sample phase and amplitude rapidly. By adjusting the size of a tiny aperture under the illumination of a parallel light beam to change the illumination on the sample step by step and recording the corresponding diffraction patterns sequentially, both the sample phase and amplitude can be faithfully reconstructed with a modified ptychographical iterative engine (PIE) algorithm. Since many fewer diffraction patterns are required than in common PIE and the shape, the size, and the position of the aperture need not to be known exactly, this proposed vaPIE method remarkably reduces the data acquisition time and makes PIE less dependent on the mechanical accuracy of the translation stage; therefore, the proposed technique can be potentially applied for various scientific researches.

Defective Reduction in Frozen Pie Manufacturing Process

NASA Astrophysics Data System (ADS)

Nooted, Oranuch; Tangjitsitcharoen, Somkiat

2017-06-01

The frozen pie production has a lot of defects resulting in high production cost. Failure mode and effect analysis (FMEA) technique has been applied to improve the frozen pie process. Pareto chart is also used to determine the major defects of frozen pie. There are 3 main processes that cause the defects which are the 1st freezing to glazing process, the forming process, and the folding process. The Risk Priority Number (RPN) obtained from FMEA is analyzed to reduce the defects. If RPN of each cause exceeds 45, the process will be considered to be improved and selected for the corrective and preventive actions. The results showed that RPN values decreased after the correction. Therefore, the implementation of FMEA technique can help to improve the performance of frozen pie process and reduce the defects approximately 51.9%.

Validation environment for AIPS/ALS: Implementation and results

NASA Technical Reports Server (NTRS)

Segall, Zary; Siewiorek, Daniel; Caplan, Eddie; Chung, Alan; Czeck, Edward; Vrsalovic, Dalibor

1990-01-01

The work is presented which was performed in porting the Fault Injection-based Automated Testing (FIAT) and Programming and Instrumentation Environments (PIE) validation tools, to the Advanced Information Processing System (AIPS) in the context of the Ada Language System (ALS) application, as well as an initial fault free validation of the available AIPS system. The PIE components implemented on AIPS provide the monitoring mechanisms required for validation. These mechanisms represent a substantial portion of the FIAT system. Moreover, these are required for the implementation of the FIAT environment on AIPS. Using these components, an initial fault free validation of the AIPS system was performed. The implementation is described of the FIAT/PIE system, configured for fault free validation of the AIPS fault tolerant computer system. The PIE components were modified to support the Ada language. A special purpose AIPS/Ada runtime monitoring and data collection was implemented. A number of initial Ada programs running on the PIE/AIPS system were implemented. The instrumentation of the Ada programs was accomplished automatically inside the PIE programming environment. PIE's on-line graphical views show vividly and accurately the performance characteristics of Ada programs, AIPS kernel and the application's interaction with the AIPS kernel. The data collection mechanisms were written in a high level language, Ada, and provide a high degree of flexibility for implementation under various system conditions.

Sex and the Cinema: What "American Pie" Teaches the Young

ERIC Educational Resources Information Center

Pearce, Sharyn

2006-01-01

This paper focuses on the wildly successful blockbuster "American Pie" teenpics, especially "American Pie 3--The Wedding". I argue that these films are specifically designed to appeal to teenage male audiences, and to provide lessons in sex and romance. Movies like this are especially important as they are experienced by far more teenagers than,…

No Humble Pie: The Origins and Usage of a Statistical Chart

ERIC Educational Resources Information Center

Spence, Ian

2005-01-01

William Playfair's pie chart is more than 200 years old and yet its intellectual origins remain obscure. The inspiration likely derived from the logic diagrams of Llull, Bruno, Leibniz, and Euler, which were familiar to William because of the instruction of his mathematician brother John. The pie chart is broadly popular but--despite its common…

Effects of nocturnal illumination on life-history decisions and fitness in two wild songbird species

PubMed Central

de Jong, Maaike; Ouyang, Jenny Q.; Da Silva, Arnaud; van Grunsven, Roy H. A.; Kempenaers, Bart; Visser, Marcel E.; Spoelstra, Kamiel

2015-01-01

The effects of artificial night lighting on animal behaviour and fitness are largely unknown. Most studies report short-term consequences in locations that are also exposed to other anthropogenic disturbance. We know little about how the effects of nocturnal illumination vary with different light colour compositions. This is increasingly relevant as the use of LED lights becomes more common, and LED light colour composition can be easily adjusted. We experimentally illuminated previously dark natural habitat with white, green and red light, and measured the effects on life-history decisions and fitness in two free-living songbird species, the great tit (Parus major) and pied flycatcher (Ficedula hypoleuca) in two consecutive years. In 2013, but not in 2014, we found an effect of light treatment on lay date, and of the interaction of treatment and distance to the nearest lamp post on chick mass in great tits but not in pied flycatchers. We did not find an effect in either species of light treatment on breeding densities, clutch size, probability of brood failure, number of fledglings and adult survival. The finding that light colour may have differential effects opens up the possibility to mitigate negative ecological effects of nocturnal illumination by using different light spectra. PMID:25780240

Growth of Staphylococcus aureus MF 31 on the Top and Cut Surfaces of Southern Custard Pies

PubMed Central

Preonas, D. L.; Nelson, A. I.; Ordal, Z. John; Steinberg, M. P.; Wei, L. S.

1969-01-01

A Staphylococcus strain was inoculated on the top and cut surfaces of freshly baked Southern custard pies which were then packaged in a pasteboard carton and held at 30 C. Daily plate counts of surface sections 0.3 inch (0.76 cm) in thickness were made. The top surface inoculum showed a 24-hr lag time. This was due to the protective action of a top cakelike layer as shown by homogenization of the mix and coating of the surface. Substitution of all sweeteners with dextrose completely inhibited growth on the top surface. Further addition of dextrose to lower water activity (Aw) to 0.9 prevented growth on the cut surface as well, but such pies were organoleptically unacceptable. Growth on the top surface could also be prevented by 80 μg of undissociated sorbic acid per g in combination with 100 μg of undissociated propionic acid per g in the baked pie. Growth on the cakelike top surface was always retarded longer than on the cut surface provided the packaging allowed evaporation of surface moisture. Reducing the Aw of a different type of cream pie to 0.907 prevented top surface growth. It was concluded that baked cream pies with a cakelike top layer could be marketed with a “refrigerate after opening” label, provided the package maintains the moisture gradient caused by the surface skin and either a combination of 80 μg of undissociated sorbic acid per g and 100 μg undissociated propionic acid per g is present in the baked pie or the Aw of the baked pie is 0.920 or lower. Images PMID:5803631

Variable aperture-based ptychographical iterative engine method.

PubMed

Sun, Aihui; Kong, Yan; Meng, Xin; He, Xiaoliang; Du, Ruijun; Jiang, Zhilong; Liu, Fei; Xue, Liang; Wang, Shouyu; Liu, Cheng

2018-02-01

A variable aperture-based ptychographical iterative engine (vaPIE) is demonstrated both numerically and experimentally to reconstruct the sample phase and amplitude rapidly. By adjusting the size of a tiny aperture under the illumination of a parallel light beam to change the illumination on the sample step by step and recording the corresponding diffraction patterns sequentially, both the sample phase and amplitude can be faithfully reconstructed with a modified ptychographical iterative engine (PIE) algorithm. Since many fewer diffraction patterns are required than in common PIE and the shape, the size, and the position of the aperture need not to be known exactly, this proposed vaPIE method remarkably reduces the data acquisition time and makes PIE less dependent on the mechanical accuracy of the translation stage; therefore, the proposed technique can be potentially applied for various scientific researches. (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

PIES free boundary stellarator equilibria with improved initial conditions

NASA Astrophysics Data System (ADS)

Drevlak, M.; Monticello, D.; Reiman, A.

2005-07-01

The MFBE procedure developed by Strumberger (1997 Nucl. Fusion 37 19) is used to provide an improved starting point for free boundary equilibrium computations in the case of W7-X (Nührenberg and Zille 1986 Phys. Lett. A 114 129) using the Princeton iterative equilibrium solver (PIES) code (Reiman and Greenside 1986 Comput. Phys. Commun. 43 157). Transferring the consistent field found by the variational moments equilibrium code (VMEC) (Hirshmann and Whitson 1983 Phys. Fluids 26 3553) to an extended coordinate system using the VMORPH code, a safe margin between plasma boundary and PIES domain is established. The new EXTENDER_P code implements a generalization of the virtual casing principle, which allows field extension both for VMEC and PIES equilibria. This facilitates analysis of the 5/5 islands of the W7-X standard case without including them in the original PIES computation.

Harnessing the Internet for International Exchanges on Learning Cities: The Pie Experience 2011-2013

ERIC Educational Resources Information Center

Kearns, Peter

2014-01-01

The PASCAL International Exchanges (PIE) project was developed to facilitate online exchanges of information and experience between learning cities around the world and, in doing this, to test the potential of the internet to enable such low-cost exchanges. The author provides a personal assessment of the PIE experience over the three years 2011…

Delayed Ego Strength Development in Opioid Dependent Adolescents and Young Adults.

PubMed

Abramoff, Benjamin A; Lange, Hannah L H; Matson, Steven C; Cottrill, Casey B; Bridge, Jeffrey A; Abdel-Rasoul, Mahmoud; Bonny, Andrea E

2015-01-01

Objective. To evaluate ego strengths, in the context of Erikson's framework, among adolescents and young adults diagnosed with opioid dependence as compared to non-drug using youth. Methods. Opioid dependent (n = 51) and non-drug using control (n = 31) youth completed the self-administered Psychosocial Inventory of Ego Strengths (PIES). The PIES assesses development in the framework of Erikson's ego strength stages. Multivariate linear regression modeling assessed the independent association of the primary covariate (opioid dependent versus control) as well as potential confounding variables (e.g., psychiatric comorbidities, intelligence) with total PIES score. Results. Mean total PIES score was significantly lower in opioid dependent youth (231.65 ± 30.39 opioid dependent versus 270.67 ± 30.06 control; p < 0.01). Evaluation of the PIES subscores found significant (p < 0.05) delays in all ego strength areas (hope, will, purpose, competence, fidelity, love, care, and wisdom). When adjusting for potential confounders, opioid dependence remained a significant (p < 0.001) independent predictor of total PIES score. Conclusion. Adolescents with opioid dependence demonstrated significant delays in ego strength development. A treatment approach acknowledging this delay may be needed in the counseling and treatment of adolescents with opioid dependence.

Delayed Ego Strength Development in Opioid Dependent Adolescents and Young Adults

PubMed Central

Abramoff, Benjamin A.; Lange, Hannah L. H.; Matson, Steven C.; Cottrill, Casey B.; Bridge, Jeffrey A.; Abdel-Rasoul, Mahmoud; Bonny, Andrea E.

2015-01-01

Objective. To evaluate ego strengths, in the context of Erikson's framework, among adolescents and young adults diagnosed with opioid dependence as compared to non-drug using youth. Methods. Opioid dependent (n = 51) and non-drug using control (n = 31) youth completed the self-administered Psychosocial Inventory of Ego Strengths (PIES). The PIES assesses development in the framework of Erikson's ego strength stages. Multivariate linear regression modeling assessed the independent association of the primary covariate (opioid dependent versus control) as well as potential confounding variables (e.g., psychiatric comorbidities, intelligence) with total PIES score. Results. Mean total PIES score was significantly lower in opioid dependent youth (231.65 ± 30.39 opioid dependent versus 270.67 ± 30.06 control; p < 0.01). Evaluation of the PIES subscores found significant (p < 0.05) delays in all ego strength areas (hope, will, purpose, competence, fidelity, love, care, and wisdom). When adjusting for potential confounders, opioid dependence remained a significant (p < 0.001) independent predictor of total PIES score. Conclusion. Adolescents with opioid dependence demonstrated significant delays in ego strength development. A treatment approach acknowledging this delay may be needed in the counseling and treatment of adolescents with opioid dependence. PMID:26664819

49 CFR 40.403 - Must a service agent notify its clients when the Department issues a PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Must a service agent notify its clients when the... Must a service agent notify its clients when the Department issues a PIE? (a) As a service agent, if... clients, in writing, about the issuance, scope, duration, and effect of the PIE. You may meet this...

Food Preparation Studies

DTIC Science & Technology

1974-11-01

delivery to the satellites. Specialty baked goods such as cakes, brownies, bars, cookies , pies, tortes, and coffee cakes will be made at the CFPF...products (cakes, rolls, brownies, pie crusts, and tortes) will be made with mixes, but cookies , bars, and coffee cakes generally will be made from...scratch. Production of baked goods requires the following specialized equipment: • Planetary mixers • Dough mixers • Sheeters • Pie machines

Improved sample utilization in thermal ionization mass spectrometry isotope ratio measurements: refined development of porous ion emitters for nuclear forensic applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baruzzini, Matthew Louis

The precise and accurate determination of isotopic composition in nuclear forensic samples is vital for assessing origin, intended use and process history. Thermal ionization mass spectrometry (TIMS) is widely accepted as the gold standard for high performance isotopic measurements and has long served as the workhorse in the isotopic ratio determination of nuclear materials. Nuclear forensic and safeguard specialists have relied heavily on such methods for both routine and atypical e orts. Despite widespread use, TIMS methods for the assay of actinide systems continue to be hindered by poor ionization e ciency, often less than tenths of a percent; themore » majority of a sample is not measured. This represents a growing challenge in addressing nextgeneration nuclear detection needs by limiting the ability to analyze ultratrace quantities of high priority elements that could potentially provide critical nuclear forensic signatures. Porous ion emitter (PIE) thermal ion sources were developed in response to the growing need for new TIMS ion source strategies for improved ionization e ciency, PIEs have proven to be simple to implement, straightforward approach to boosting ion yield. This work serves to expand the use of PIE techniques for the analysis of trace quantities of plutonium and americium. PIEs exhibited superior plutonium and americium ion yields when compared to direct lament loading and the resin bead technique, one of the most e cient methods for actinide analysis, at similar mass loading levels. Initial attempts at altering PIE composition for the analysis of plutonium proved to enhance sample utilization even further. Preliminary investigations of the instrumental fractionation behavior of plutonium and uranium analyzed via PIE methods were conducted. Data collected during these initial trial indicate that PIEs fractionate in a consistent, reproducible manner; a necessity for high precision isotope ratio measurements. Ultimately, PIEs methods were applied for the age determination of various uranium isotopic standards. PIEs did not exhibit signi cant advantages for the determination of model ages when compared to traditional laments; however, this trial was able to provide valuable insight for guiding future investigations.« less

A comprehensive Reputation mechanism for ubiquitous healthcare environment exploiting cloud model.

PubMed

Athanasiou, Georgia; Lymberopoulos, Dimitrios

2016-08-01

Absence of trust foundations may outweigh benefits of ubiquitous and personalized mental healthcare supervision provided within a Ubiquitous Healthcare environment (UH). Trust is composed by patient's Personal Interaction Experience (PIE) and social entourage accumulated PIE, i.e. Reputation (R). In this paper, a cloud-based Reputation mechanism is proposed. Since PIE is the elementary trust information source, also an Updating mechanism of PIE, is introduced, in this paper. Cloud materialization of combined mechanisms provides adaptability to UH Providers' dynamic behavior, facilitates detection of milking behaviors and complex malicious attacks while meets the challenge of limited accuracy in case of data sparseness. The effectiveness of the proposed mechanisms is verified via simulation in MATLAB.

An Outbreak of Human Listeriosis in England between 2010 and 2012 Associated with the Consumption of Pork Pies.

PubMed

Awofisayo-Okuyelu, A; Arunachalam, N; Dallman, T; Grant, K A; Aird, H; McLauchlin, J; Painset, A; Amar, C

2016-05-01

An outbreak of listeriosis in England affecting 14 people between 2010 and 2012 and linked to the consumption of pork pies was investigated. All 14 individuals were older than 55 years, 12 were men, and 10 reported the presence of an underlying condition. All were resident in or had visited either of two English regions and were infected with the same strain of Listeria monocytogenes. In interviews with 12 patients, 9 reported eating pork pies, and individuals that consumed pork pies were significantly more likely to be infected with an outbreak strain than were individuals with sporadic cases of listeriosis infections in England from 2010 to 2012. Pork pies were purchased from seven retailers in South Yorkshire or the East Midlands, and the outbreak strain was recovered from pork pies supplied by only the producer in South Yorkshire. The outbreak strain was also recovered from samples of finished product and from environmental samples collected from the manufacturer. The likely source of contamination was environmental sites within the manufacturing environment, and the contamination was associated with the process of adding gelatin to the pies after cooking. Inadequate temperature control and poor hygienic practices at one of the retailers were also identified as possible contributory factors allowing growth of the pathogen. Following improvements in manufacturing practices and implementation of additional control measures at the retailers' premises, L. monocytogenes was not recovered from subsequent food and environmental samples, and the outbreak strain was not detected in further individuals with listeriosis in England.

The Dolinar Receiver in an Information Theoretic Framework

NASA Technical Reports Server (NTRS)

Erkmen, Baris I.; Birnbaum, Kevin M.; Moision, Bruce E.; Dolinar, Samuel J.

2011-01-01

Optical communication at the quantum limit requires that measurements on the optical field be maximally informative, but devising physical measurements that accomplish this objective has proven challenging. The Dolinar receiver exemplifies a rare instance of success in distinguishing between two coherent states: an adaptive local oscillator is mixed with the signal prior to photodetection, which yields an error probability that meets the Helstrom lower bound with equality. Here we apply the same local-oscillator-based architecture with aninformation-theoretic optimization criterion. We begin with analysis of this receiver in a general framework for an arbitrary coherent-state modulation alphabet, and then we concentrate on two relevant examples. First, we study a binary antipodal alphabet and show that the Dolinar receiver's feedback function not only minimizes the probability of error, but also maximizes the mutual information. Next, we study ternary modulation consistingof antipodal coherent states and the vacuum state. We derive an analytic expression for a near-optimal local oscillator feedback function, and, via simulation, we determine its photon information efficiency (PIE). We provide the PIE versus dimensional information efficiency (DIE) trade-off curve and show that this modulation and the our receiver combination performs universally better than (generalized) on-off keying plus photoncounting, although, the advantage asymptotically vanishes as the bits-per-photon diverges towards infinity.

The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene Products.

PubMed

Rattay, Stephanie; Trilling, Mirko; Megger, Dominik A; Sitek, Barbara; Meyer, Helmut E; Hengel, Hartmut; Le-Trilling, Vu Thuy Khanh

2015-08-01

Transcription of mouse cytomegalovirus (MCMV) immediate early ie1 and ie3 is controlled by the major immediate early promoter/enhancer (MIEP) and requires differential splicing. Based on complete loss of genome replication of an MCMV mutant carrying a deletion of the ie3-specific exon 5, the multifunctional IE3 protein (611 amino acids; pIE611) is considered essential for viral replication. Our analysis of ie3 transcription resulted in the identification of novel ie3 isoforms derived from alternatively spliced ie3 transcripts. Construction of an IE3-hemagglutinin (IE3-HA) virus by insertion of an in-frame HA epitope sequence allowed detection of the IE3 isoforms in infected cells, verifying that the newly identified transcripts code for proteins. This prompted the construction of an MCMV mutant lacking ie611 but retaining the coding capacity for the newly identified isoforms ie453 and ie310. Using Δie611 MCMV, we demonstrated the dispensability of the canonical ie3 gene product pIE611 for viral replication. To determine the role of pIE611 for viral gene expression during MCMV infection in an unbiased global approach, we used label-free quantitative mass spectrometry to delineate pIE611-dependent changes of the MCMV proteome. Interestingly, further analysis revealed transcriptional as well as posttranscriptional regulation of MCMV gene products by pIE611. Cytomegaloviruses are pathogenic betaherpesviruses persisting in a lifelong latency from which reactivation can occur under conditions of immunosuppression, immunoimmaturity, or inflammation. The switch from latency to reactivation requires expression of immediate early genes. Therefore, understanding of immediate early gene regulation might add insights into viral pathogenesis. The mouse cytomegalovirus (MCMV) immediate early 3 protein (611 amino acids; pIE611) is considered essential for viral replication. The identification of novel protein isoforms derived from alternatively spliced ie3 transcripts prompted the construction of an MCMV mutant lacking ie611 but retaining the coding capacity for the newly identified isoforms ie453 and ie310. Using Δie611 MCMV, we demonstrated the dispensability of the canonical ie3 gene product pIE611 for viral replication and delineated pIE611-dependent changes of the MCMV proteome. Our findings have fundamental implications for the interpretation of earlier studies on pIE3 functions and highlight the complex orchestration of MCMV gene regulation. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Promotion effect of H2 on ethanol oxidation and NOx reduction with ethanol over Ag/Al2O3 catalyst.

PubMed

Yu, Yunbo; Li, Yi; Zhang, Xiuli; Deng, Hua; He, Hong; Li, Yuyang

2015-01-06

The catalytic partial oxidation of ethanol and selective catalytic reduction of NOx with ethanol (ethanol-SCR) over Ag/Al2O3 were studied using synchrotron vacuum ultraviolet (VUV) photoionization mass spectrometry (PIMS). The intermediates were identified by PIMS and their photoionization efficiency (PIE) spectra. The results indicate that H2 promotes the partial oxidation of ethanol to acetaldehyde over Ag/Al2O3, while the simultaneously occurring processes of dehydration and dehydrogenation were inhibited. H2 addition favors the formation of ammonia during ethanol-SCR over Ag/Al2O3, the occurrence of which creates an effective pathway for NOx reduction by direct reaction with NH3. Simultaneously, the enhancement of the formation of ammonia benefits its reaction with surface enolic species, resulting in producing -NCO species again, leading to enhancement of ethanol-SCR over Ag/Al2O3 by H2. Using VUV-PIMS, the reactive vinyloxy radical was observed in the gas phase during the NOx reduction by ethanol for the first time, particularly in the presence of H2. Identification of such a reaction occurring in the gas phase may be crucial for understanding the reaction pathway of HC-SCR over Ag/Al2O3.

Retail Buildings: Assessing and Reducing Plug and Process Loads in Retail Buildings (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2013-04-01

Plug and process loads (PPLs) in commercial buildings account for almost 5% of U.S. primary energy consumption. Minimizing these loads is a primary challenge in the design and operation of an energy-efficient building. PPLs are not related to general lighting, heating, ventilation, cooling, and water heating, and typically do not provide comfort to the occupants. They use an increasingly large fraction of the building energy use pie because the number and variety of electrical devices have increased along with building system efficiency. Reducing PPLs is difficult because energy efficiency opportunities and the equipment needed to address PPL energy use inmore » retail spaces are poorly understood.« less

[In Process Citation].

PubMed

López-Fuenzalida, Antonio; Rodríguez Canales, Carolina; Reyes Ponce, Álvaro; Contreras Molina, Ángela; Fernández Quezada, Javiera; Aguirre Polanco, Carolina

2016-03-25

Introducción: dado el incremento del sobrepeso y obesidad infantil, es relevante estudiar no solo las consecuencias metabólicas, sino también aquellas de índole musculoesqueléticas que pueden afectar la funcionalidad motriz, como es el pie plano, en esta población. Objetivo: identificar la asociación entre el estado nutricional y la prevalencia de pie plano en niños y niñas chilenos de 6 a 10 años. Métodos: el z-score del índice de masa corporal (IMC) y el registro y análisis de las huellas plantares según la metodología de Hernández-Corvo fue llevado a cabo en 388 escolares (52,3% niñas). Un test de diferencia para dos proporciones fue utilizado para evaluar las diferencias entre los grupos. Se considera una significancia estadística con p ≤ 0,05. Resultados: la prevalencia del exceso de peso fue de más del 40%. Esta prevalencia fue más alta en las niñas (47,8%) que en los niños (42,7%). La prevalencia de pie plano en todos los niños fue del 17%, presentando valores más elevados el pie derecho (18,3%) que el izquierdo (15,7%). Hay un incremento significativo de la prevalencia de pie plano en los niños obesos en relación con los niños con sobrepeso y normopeso. Conclusión: el estado nutricional está asociado con incrementos en la prevalencia de pie plano en niños. En la población infantil de 6 a 10 años de edad, la obesidad está asociada con la alteración morfológica del pie.

Reverse engineering a gene network using an asynchronous parallel evolution strategy

PubMed Central

2010-01-01

Background The use of reverse engineering methods to infer gene regulatory networks by fitting mathematical models to gene expression data is becoming increasingly popular and successful. However, increasing model complexity means that more powerful global optimisation techniques are required for model fitting. The parallel Lam Simulated Annealing (pLSA) algorithm has been used in such approaches, but recent research has shown that island Evolutionary Strategies can produce faster, more reliable results. However, no parallel island Evolutionary Strategy (piES) has yet been demonstrated to be effective for this task. Results Here, we present synchronous and asynchronous versions of the piES algorithm, and apply them to a real reverse engineering problem: inferring parameters in the gap gene network. We find that the asynchronous piES exhibits very little communication overhead, and shows significant speed-up for up to 50 nodes: the piES running on 50 nodes is nearly 10 times faster than the best serial algorithm. We compare the asynchronous piES to pLSA on the same test problem, measuring the time required to reach particular levels of residual error, and show that it shows much faster convergence than pLSA across all optimisation conditions tested. Conclusions Our results demonstrate that the piES is consistently faster and more reliable than the pLSA algorithm on this problem, and scales better with increasing numbers of nodes. In addition, the piES is especially well suited to further improvements and adaptations: Firstly, the algorithm's fast initial descent speed and high reliability make it a good candidate for being used as part of a global/local search hybrid algorithm. Secondly, it has the potential to be used as part of a hierarchical evolutionary algorithm, which takes advantage of modern multi-core computing architectures. PMID:20196855

Epidemiology of ocular disorders presumed to be inherited in three large Italian dog breeds in Italy.

PubMed

Guandalini, Adolfo; Di Girolamo, Nicola; Santillo, Daniele; Andreani, Valentina; Corvi, Roberta; Bandini, Marina; Peruccio, Claudio

2017-09-01

To describe the epidemiology and the types of eye disorders that are presumed to be inherited (PIED) in three large Italian dog breeds. Three large Italian dog breeds: Neapolitan Mastiff (FCI code: 197), Maremma Sheepdog (FCI code: 201), and Italian Corso dog (FCI code: 343). All dogs that underwent a complete ophthalmic examination between 1992 and 2012 were included in this prospective observational study. The prevalence of eye disorders with 95% confidence intervals was reported for presumed healthy dogs and for dogs referred to a veterinary center for an ophthalmic consultation. Univariate and multivariate logistic regression techniques were used to generate odds ratios. Of 605 dogs examined during the study period, 351 dogs were affected by at least one PIED (58%; 95% CI: 54-62%). The prevalence of PIED was significantly lower in dogs presented for ophthalmic examination (53.8%) as compared to presumed healthy dogs (62.2%)(OR: 1.4; 95% CI: 1.02-1.9; P = 0.037). Also after multivariate adjustment for the period of observation, the odds of Neapolitan Mastiff (92.1%; OR: 21.4; 95% CI: 11.1-41.4) and of Cane Corso (57.7%; OR: 2.5; 95% CI: 1.7-3.6) suffering a PIED were greater than the Maremma Sheepdog (35.4%). The most common PIED in each breed were entropion (24.3% of all the PIED) in the Neapolitan Mastiff, ectropion (36.6%) in the Corso dog, and cataract (27.9%) in the Maremma Sheepdog. Clinicians should be aware that three large Italian dog breeds frequently suffer PIED. Breed standards should be reconsidered, and breeding programs should be directed at limiting such disorders. © 2016 American College of Veterinary Ophthalmologists.

Report on FY16 Low-dose Metal Fuel Irradiation and PIE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Edmondson, Philip D.

2016-09-01

This report gives an overview of the efforts into the low-dose metal fuel irradiation and PIE as part of the Fuel Cycle Research & Development (FCRD) Advanced Fuels Campaign (AFC) milestone M3FT-16OR020303031. The current status of the FCT and FCRP irradiation campaigns are given including a description of the materials that have been irradiated, analysis of the passive temperature monitors, and the initial PIE efforts of the fuel samples.

Effects of nocturnal illumination on life-history decisions and fitness in two wild songbird species.

PubMed

de Jong, Maaike; Ouyang, Jenny Q; Da Silva, Arnaud; van Grunsven, Roy H A; Kempenaers, Bart; Visser, Marcel E; Spoelstra, Kamiel

2015-05-05

The effects of artificial night lighting on animal behaviour and fitness are largely unknown. Most studies report short-term consequences in locations that are also exposed to other anthropogenic disturbance. We know little about how the effects of nocturnal illumination vary with different light colour compositions. This is increasingly relevant as the use of LED lights becomes more common, and LED light colour composition can be easily adjusted. We experimentally illuminated previously dark natural habitat with white, green and red light, and measured the effects on life-history decisions and fitness in two free-living songbird species, the great tit (Parus major) and pied flycatcher (Ficedula hypoleuca) in two consecutive years. In 2013, but not in 2014, we found an effect of light treatment on lay date, and of the interaction of treatment and distance to the nearest lamp post on chick mass in great tits but not in pied flycatchers. We did not find an effect in either species of light treatment on breeding densities, clutch size, probability of brood failure, number of fledglings and adult survival. The finding that light colour may have differential effects opens up the possibility to mitigate negative ecological effects of nocturnal illumination by using different light spectra. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

The NURBS curves in modelling the shape of the boundary in the parametric integral equations systems for solving the Laplace equation

NASA Astrophysics Data System (ADS)

Zieniuk, Eugeniusz; Kapturczak, Marta; Sawicki, Dominik

2016-06-01

In solving of boundary value problems the shapes of the boundary can be modelled by the curves widely used in computer graphics. In parametric integral equations system (PIES) such curves are directly included into the mathematical formalism. Its simplify the way of definition and modification of the shape of the boundary. Until now in PIES the B-spline, Bézier and Hermite curves were used. Recent developments in the computer graphics paid our attention, therefore we implemented in PIES possibility of defining the shape of boundary using the NURBS curves. The curves will allow us to modeling different shapes more precisely. In this paper we will compare PIES solutions (with applied NURBS) with the solutions existing in the literature.

Sub-aperture switching based ptychographic iterative engine (sasPIE) method for quantitative imaging

NASA Astrophysics Data System (ADS)

Sun, Aihui; Kong, Yan; Jiang, Zhilong; Yu, Wei; Liu, Fei; Xue, Liang; Wang, Shouyu; Liu, Cheng

2018-03-01

Though ptychographic iterative engine (PIE) has been widely adopted in the quantitative micro-imaging with various illuminations as visible light, X-ray and electron beam, the mechanical inaccuracy in the raster scanning of the sample relative to the illumination always degrades the reconstruction quality seriously and makes the resolution reached much lower than that determined by the numerical aperture of the optical system. To overcome this disadvantage, the sub-aperture switching based PIE method is proposed: the mechanical scanning in the common PIE is replaced by the sub-aperture switching, and the reconstruction error related to the positioning inaccuracy is completely avoided. The proposed technique remarkably improves the reconstruction quality, reduces the complexity of the experimental setup and fundamentally accelerates the data acquisition and reconstruction.

Safety Testing of AGR-2 UCO Compacts 6-4-2 and 2-3-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunn, John D.; Morris, Robert N.; Baldwin, Charles A.

2017-08-01

Post-irradiation examination (PIE) and elevated-temperature safety testing are being performed on tristructural-isotropic (TRISO) coated-particle fuel compacts from the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program second irradiation experiment (AGR-2). Details on this irradiation experiment have been previously reported [Collin 2014]. The AGR-2 PIE effort builds upon the understanding acquired throughout the AGR-1 PIE campaign [Demkowicz et al. 2015] and is establishing a database for the different AGR-2 fuel designs.

Comparison of Low-Molecular-Weight Heparins Prepared From Bovine Lung Heparin and Porcine Intestine Heparin.

PubMed

Guan, Yudong; Xu, Xiaohui; Liu, Xinyue; Sheng, Anran; Jin, Lan; Linhardt, Robert J; Chi, Lianli

2016-06-01

Currently porcine intestine is the only approved source for producing pharmaceutical heparin in most countries. Enoxaparin, prepared by benzylation and alkaline depolymerization from porcine intestine heparin, is prevalent in the anticoagulant drug market. It is predicted that porcine intestine heparin-derived enoxaparin (PIE) will encounter shortage, and expanding its production from heparins obtained from other animal tissues may, therefore, be inevitable. Bovine lung heparin is a potential alternative source for producing enoxaparin. Critical processing parameters for producing bovine lung heparin-derived enoxaparin (BLE) are discussed. Three batches of BLEs were prepared and their detailed structures were compared with PIEs using modern analytical techniques, including disaccharide composition, intact chain mapping by liquid chromatography-mass spectrometry and 2-dimensional nuclear magnetic resonance spectroscopy. The results suggested that the differences between PIEs and BLEs mainly result from N-acetylation differences derived from the parent heparins. In addition, bioactivities of BLEs were about 70% of PIEs based on anti-factor IIa and Xa chromogenic assays. We conclude that BLE has the potential to be developed as an analogue of PIE, although some challenges still remain. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Psychometric Testing of the Personal Internet Gaming Disorder Evaluation-9: A New Measure Designed to Assess Internet Gaming Disorder.

PubMed

Pearcy, Benjamin T D; Roberts, Lynne D; McEvoy, Peter M

2016-05-01

Internet Gaming Disorder (IGD) is in the early stages of recognition as a disorder, following its inclusion in the Diagnostic and Statistical Manual for Mental Disorders (DSM-5; American Psychiatric Association(1)) as a condition for further study. Existing measures of Internet gaming pathology are limited in their ability to measure IGD as defined in the DSM-5. We present the initial development and validation of a new measure derived from the proposed DSM-5 criteria for IGD, the Personal Internet Gaming Disorder Evaluation-9 (PIE-9). A student sample (n = 119) and a community sample (n = 285), sourced through a variety of online gaming forums, completed an online survey comprising the new measure, existing measures of IGD, and a range of health and demographic questions. Exploratory and confirmatory factor analysis supported a single factor structure for the 9-item PIE-9. Internal consistency (α = 0.89) and test-retest reliability (intraclass correlation [ICC] = 0.77) were high. Convergent validity was demonstrated with similar gaming addiction measures. Predictive validity was established through significant differences in distress and disability between those who met the criteria for IGD and those who did not. The distress and disability associated with meeting IGD criteria fell within the range of other common DSM-5 disorders. Preliminary testing of the PIE-9 has demonstrated that it is an efficient and straightforward measure for use in further research of IGD, and as a potential screening measure in clinical practice.

The pie-crusting technique using a blade knife for medial collateral ligament release is unreliable in varus total knee arthroplasty.

PubMed

Kwak, Dai-Soon; In, Yong; Kim, Tae Kyun; Cho, Han Suk; Koh, In Jun

2016-01-01

Despite the documented clinical efficacy of the pie-crusting technique for medial collateral ligament (MCL) release in varus total knee arthroplasty, its quantitative effects on medial gaps and safety remain unclear. This study was undertaken to determine the efficacy (quantitative effect and consistency of the number of punctures) and the safety (frequency of early over-release) of the pie-crusting technique for MCL release. From ten pairs of cadaveric knees, one knee from each pair was randomly assigned to undergo pie crusting in extension (group E) or in flexion (group F). Pie crusting was performed in the superficial MCL using a blade until over-release occurred. After every puncture, the incremental medial gap increase was recorded, and the number of punctures required for 2- or 4-mm gap increases was assessed. In group E, the extension gap increased from 0.8 to 5.0 mm and the flexion gap increased from 0.8 to 3.0 mm. In group F, the extension gap increased from 1.0 to 3.0 mm and the flexion gap increased from 2.6 to 6.0 mm. However, the gap increments were inconsistent with those that followed the preceding blade punctures, and the number of punctures required to increase the gaps by 2 or 4 mm was variable. The number of punctures leading to over-release in group E and group F was 6 ± 1 and 3 ± 1 punctures, respectively. Overall, 70% of over-release occurred earlier than the average number of punctures leading to over-release. Pie crusting led to unpredictable gap increments and to frequent early over-release. Surgeons should decide carefully before using the pie-crusting technique for MCL release and should be cautious of performing throughout the procedure, especially when performing in a flexed knee. Therapeutic study, Level I.

Selective traffic enforcement program for occupant restraints

DOT National Transportation Integrated Search

1987-04-01

Increased compliance with New York's occupant restraint law was the result of two different traffic enforcement and public information and education (PI&E) programs. The police in one community conducted four PI&E campaigns highlighting increased enf...

Evaluation of child safety seat enforcement strategies

DOT National Transportation Integrated Search

1989-09-01

Nine community programs designed to increase child safety seat (CSS) use through public information and education (PI&E) and enforcement were evaluated. An administrative evaluation documented each site's PI&E and enforcement activties. A total of 5,...

The psychosocial inventory of ego strengths: examination of theory and psychometric properties.

PubMed

Markstrom, Carol A; Marshall, Sheila K

2007-02-01

The psychosocial inventory of ego strengths (PIES) was devised as a measure of Erikson's eight ego strengths. The present investigation extended previous research through examination of the validity and reliability of the PIES among 502 high school students. The study also included an appraisal of Erikson's ego strengths as indices of psychosocial well-being. Reliability of the subscales of the PIES was shown through acceptable Cronbach's alphas. As expected, higher scores on ego strengths were positively correlated with psychosocial indictors of identity achievement, self-esteem, locus of control, empathic concern, perspective-taking, and positive forms of coping. Lower scores on ego strengths were related to less desirable psychosocial constructs. Biological sex and age differences also are reported. Based on the findings, the study offers validation of psychosocial theory. As well, the PIES is recommended for use among high school students.

Relating dynamic perception of reformulated cheese pies to consumers' expectations of satiating ability.

PubMed

Marcano, J; Varela, P; Cunha, L M; Fiszman, S

2015-12-01

Designing satiating food is not an easy task. Food reformulation is normally done by altering the proportion of basic ingredients or by adding new minor ingredients. In general, the texture varies concomitantly with these changes, altering the way the food is processed orally and the complete eating experience. This highlights the interest of discovering how variations in minor ingredients influence texture and how this affects the dynamics of the oral trajectory. Six cheese pie formulations were prepared: basic recipe (Base), no egg (-Egg), no corn starch (-Corn starch) no sugar (-Sugar), added diary cream (+Cream) and extra skimmed milk powder (+Milk powder). Temporal dominance of sensations was used to show that the appearance and disappearance of each texture sensation dominance experienced in the mouth during the eating process differed among the six pies, as did their relation to the consumers' expectation of satiating capacity scores and to the changes in composition. Two extreme behaviors were found: suppression of egg/addition of extra milk powder made the pies initially drier and harder, while suppression of corn starch/addition of cream gave the samples a soft, moist early sensation. The former elicited higher expectations of satiating capacity. In addition, overall liking, liking evolving with time (dynamic liking) and the level of several key texture attributes' divergence from those of an "ideal" cheese pie were evaluated on bipolar just-about-right scales and through penalty analysis to gain insights into potential directions for reformulating acceptable pies. Copyright © 2015 Elsevier Ltd. All rights reserved.

49 CFR 40.409 - What does the issuance of a PIE mean to transportation employers?

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.409... Department issues a PIE concerning Service Agent N on September 1. All tests conducted using N's services...

What happens in an estuary doesn't stay there: patterns of biotic connectivity resulting from long term ecological research

USGS Publications Warehouse

Mather, Martha E.; Finn, John T.; Kennedy, Christina G.; Deegan, Linda A.; Smith, Joseph M.

2013-01-01

The paucity of data on migratory connections and an incomplete understanding of how mobile organisms use geographically separate areas have been obstacles to understanding coastal dynamics. Research on acoustically tagged striped bass (Morone saxatilis) at the Plum Island Ecosystems (PIE) Long Term Ecological Research site, Massachusetts, documents intriguing patterns of biotic connectivity (i.e., long-distance migration between geographically distinct areas). First, the striped bass tagged at PIE migrated southward along the coast using different routes. Second, these tagged fish exhibited strong fidelity and specificity to PIE. For example, across multiple years, tagged striped bass resided in PIE waters for an average of 1.5-2.5 months per year (means: 51-72 days; range 2-122 days), left this estuary in fall, then returned in subsequent years. Third, this specificity and fidelity connected PIE to other locations. The fish exported nutrients and energy to at least three other coastal locations through biomass added as growth. These results demonstrate that what happens in an individual estuary can affect other estuaries. Striped bass that use tightly connected routes to feed in specific estuaries should have greater across-system impacts than fish that are equally likely to go anywhere. Consequently, variations in when, where, and how fish migrate can alter across-estuary impacts.

49 CFR 40.407 - May a service agent ask to have a PIE reduced or terminated?

Code of Federal Regulations, 2010 CFR

2010-10-01

... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.407 May a service... reconsideration of the decision to issue the PIE. (b) Your request must be in writing and supported with...

Geometry for Pie Lovers.

ERIC Educational Resources Information Center

Fisher, William

1982-01-01

An approach to the instruction of maxima and minima problems that works with tools of geometry and algebra is presented. The focus is on a classic pie-cutting problem, which is viewed as an interesting and instructive task that is an excellent application of transformation geometry. (MP)

The Cassini Solstice Mission: Streamlining Operations by Sequencing with PIEs

NASA Technical Reports Server (NTRS)

Vandermey, Nancy; Alonge, Eleanor K.; Magee, Kari; Heventhal, William

2014-01-01

The Cassini Solstice Mission (CSM) is the second extended mission phase of the highly successful Cassini/Huygens mission to Saturn. Conducted at a much-reduced funding level, operations for the CSM have been streamlined and simplified significantly. Integration of the science timeline, which involves allocating observation time in a balanced manner to each of the five different science disciplines (with representatives from the twelve different science instruments), has long been a labor-intensive endeavor. Lessons learned from the prime mission (2004-2008) and first extended mission (Equinox mission, 2008-2010) were utilized to design a new process involving PIEs (Pre-Integrated Events) to ensure the highest priority observations for each discipline could be accomplished despite reduced work force and overall simplification of processes. Discipline-level PIE lists were managed by the Science Planning team and graphically mapped to aid timeline deconfliction meetings prior to assigning discrete segments of time to the various disciplines. Periapse segments are generally discipline-focused, with the exception of a handful of PIEs. In addition to all PIEs being documented in a spreadsheet, allocated out-of-discipline PIEs were entered into the Cassini Information Management System (CIMS) well in advance of timeline integration. The disciplines were then free to work the rest of the timeline internally, without the need for frequent interaction, debate, and negotiation with representatives from other disciplines. As a result, the number of integration meetings has been cut back extensively, freeing up workforce. The sequence implementation process was streamlined as well, combining two previous processes (and teams) into one. The new Sequence Implementation Process (SIP) schedules 22 weeks to build each 10-week-long sequence, and only 3 sequence processes overlap. This differs significantly from prime mission during which 5-week-long sequences were built in 24 weeks, with 6 overlapping processes.

International Workshop on Characterization and PIE Needs for Fundamental Understanding of Fuels Performance and Safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Listed

2011-12-01

The International Workshop on Characterization and PIE Needs to Support Science-Based Development of Innovative Fuels was held June 16-17, 2011, in Paris, France. The Organization for Economic Co-operation and Development (OECD), Nuclear Energy Agency (NEA) Working Party on the Fuel Cycle (WPFC) sponsored the workshop to identify gaps in global capabilities that need to be filled to meet projected needs in the 21st century. First and foremost, the workshop brought nine countries and associated international organizations, together in support of common needs for nuclear fuels and materials testing, characterization, PIE, and modeling capabilities. Finland, France, Germany, Republic of Korea, Russianmore » Federation, Sweden, Switzerland, United Kingdom, United States of America, IAEA, and ITU (on behalf of European Union Joint Research Centers) discussed issues and opportunities for future technical advancements and collaborations. Second, the presentations provided a base level of understanding of current international capabilities. Three main categories were covered: (1) status of facilities and near term plans, (2) PIE needs from fuels engineering and material science perspectives, and (3) novel PIE techniques being developed to meet the needs. The International presentations provided valuable data consistent with the outcome of the National Workshop held in March 2011. Finally, the panel discussion on 21st century PIE capabilities, created a unified approach for future collaborations. In conclusion, (1) existing capabilities are not sufficient to meet the needs of a science-based approach, (2) safety issues and fuels behavior during abnormal conditions will receive more focus post-Fukushima; therefore we need to adopt our techniques to those issues, and (3) International collaboration is needed in the areas of codes and standards development for the new techniques.« less

Selective Medial Release Technique Using the Pie-Crusting Method for Medial Tightness During Primary Total Knee Arthroplasty.

PubMed

Ha, Chul-Won; Park, Yong-Beom; Lee, Choong-Hee; Awe, Soo-Ik; Park, Yong-Geun

2016-05-01

The pie-crusting method is popular in releasing lateral tightness during primary total knee arthroplasty (TKA) but is not well described for medial release. We established a selective medial release technique using the pie-crusting technique and investigated the effectiveness and safety of the technique during primary TKA. We retrospectively reviewed 729 primary TKAs with varus deformity between October 2009 and June 2012. Medial tightness in flexion was released by traditional subperiosteal stripping for the anterior portion of the medial collateral ligament (aMCL). Medial tightness in extension was released by the pie crusting for the tight fibers in the posterior portion of the MCL and/or posteromedial corner structures (pMCL/PMCS). Clinical outcomes were evaluated by Knee Society (KS) scores and the Western Ontario and McMaster Universities Osteoarthritis Index. Any complications, including late medial instability that may be related to our surgical technique, were carefully inspected. Among the 729 knees, 170 (23.3%) required subperiosteal stripping for balancing in flexion only, 186 (25.5%) required the pie-crusting for balancing in extension only and 142 (19.5%) required subperiosteal stripping and the pie-crusting for balancing in flexion and extension. The KS knee score was improved from 52.5 to 83.4, KS function score from 58.2 to 91.9, and Western Ontario and McMaster Universities Osteoarthritis Index from 42.7 to 21.8 (P < .001, all). No specific complications related to our technique were identified. The selective medial release technique appears to be an effective and safe method to obtain a balanced mediolateral gap in primary TKA. Copyright © 2016 Elsevier Inc. All rights reserved.

49 CFR 40.401 - How does the Department notify employers and the public about a PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.401.... (b) When the Director issues a PIE, he or she adds to the List the name and address of the service...

Syndrome de larva migrans cutanée sur pied malformé (à propos d'un cas)

PubMed Central

Benbella, Imane; Khalki, Hanane; Lahmadi, Khalid; Kouara, Sara; Abbadi, Abderrahim; Er-rami, Mohammed

2016-01-01

Le syndrome de larva migrans cutanée est une dermite sous cutanée causée par des larves d'ankylostomes d'animaux en impasse parasitaire chez l'homme. L'infestation transcutanée est favorisée par le contact avec le sol contaminé par les larves du parasite. Nous rapportons le cas d'un nourrisson de 15 mois, originaire de Guinée-Bissau, atteint d'un syndrome de larva migrans cutanée sur un pied malformé. Cette malformation sous forme d'une syndactylie associée à une tuméfaction du pied, était à l'origine d'un retard d'acquisition de la station debout. De même, on a rapporté une notion de pieds nus, vue la difficulté de chausser le pied malformé du patient. Tous ces facteurs auraient contribués à favoriser l'infestation du malade par les larves du nématode. PMID:27217876

On the Fair Division of Multiple Stochastic Pies to Multiple Agents within the Nash Bargaining Solution

PubMed Central

Karmperis, Athanasios C.; Aravossis, Konstantinos; Tatsiopoulos, Ilias P.; Sotirchos, Anastasios

2012-01-01

The fair division of a surplus is one of the most widely examined problems. This paper focuses on bargaining problems with fixed disagreement payoffs where risk-neutral agents have reached an agreement that is the Nash-bargaining solution (NBS). We consider a stochastic environment, in which the overall return consists of multiple pies with uncertain sizes and we examine how these pies can be allocated with fairness among agents. Specifically, fairness is based on the Aristotle’s maxim: “equals should be treated equally and unequals unequally, in proportion to the relevant inequality”. In this context, fairness is achieved when all the individual stochastic surplus shares which are allocated to agents are distributed in proportion to the NBS. We introduce a novel algorithm, which can be used to compute the ratio of each pie that should be allocated to each agent, in order to ensure fairness within a symmetric or asymmetric NBS. PMID:23024752

Computerized Analysis of Nutrients (CAN) System

DTIC Science & Technology

1989-11-01

1 H 24.02 PEANUT BUTTER BARS (Sugar Cookie Mix) 3.1 1 PIE CRUST 3 I 1.01. PIE CRUST ( Dough Rolling Method) 3 I 1.02 PIE CRUST (Manual Method) 3 I 2... COOKIES -CHOC COV MR6801 6 .0 .0 99.0 PEANUT BUTTER MRE & MR6906 6 .0 .0 99.0 SOUR CREAM 801056 5 .0 .0 99.0 PINEAPPLE CANNED IN 809268 5 .0 .0 99.1...CHOCOLATE CO MR6803 3 .0 .0 99.6 CAKE-CHERRY NUT MR6804 3 .0 .0 99.6 COOKIES , OREO OREO 3 .0 .0 99.7 SODA FRUIT 004060 2 .0 .0 99.7 OLIVE-GREEN 014060

Mom, Apple Pie, and the American Dream.

ERIC Educational Resources Information Center

Grambs, Jean Dresden

1982-01-01

Discusses how the mom-and-apple-pie facet of the American dream no longer seems to be working. Ways to redefine that dream so that women, men, children, and families are comfortable with each other and are able to develop a mutual dependence which also allows for mutual independence are examined. (RM)

Reflections on "Petit Battement sur le Cou de Pied": Is It Still Relevant?

ERIC Educational Resources Information Center

Paskevska, Anna

2007-01-01

This article presents multiple perspectives of "petit battement sur le cou de pied". These perspectives include historical, biomechanical, and pedagogic points of view. The article offers useful information for ballet specialists and applied research studies aimed at ballet pedagogy. (Contains 2 tables and 5 figures.)

Electron Acceptors Based on α-Substituted Perylene Diimide (PDI) for Organic Solar Cells

DOE PAGES

Zhao, Donglin; Wu, Qinghe; Cai, Zhengxu; ...

2016-02-20

The ortho-position functionalized perylene diimide derivatives (αPPID, αPBDT) were synthesized and used as the electron acceptors in nonfullerene organic photovoltaics. Due to the good planarity of ortho-position functionalized PDI, the αPPID and αPBDT show strong tendency to form aggregate because of their enhanced intermolecular pie-pie interaction. Moreover, they maintain the pure domains and the same packing order as in the pure film if they are blended with PBT7-TH and the SCLC measurement also shows the high electron mobility. The inverted OPVs employing αPDI-based compounds as acceptor and PBT7-TH as the donor give the highest PCE of 4.92 % for αPBDTmore » based device and 3.61 % for αPPID based device, which is 39 % and 4 % higher than that for their counterpart βPBDT and βPPID. The charge separation study shows the more efficient exciton dissociation at interfaces between PDI based compounds and PBT7-TH. In conclusion, the results suggest that compared to beta-substituted ones, alpha-substituted PDI derivatives are more promising electron acceptors for OPV.« less

Use of high order, periodic orbits in the PIES code

NASA Astrophysics Data System (ADS)

Monticello, Donald; Reiman, Allan

2010-11-01

We have implemented a version of the PIES code (Princeton Iterative Equilibrium SolverootnotetextA. Reiman et al 2007 Nucl. Fusion 47 572) that uses high order periodic orbits to select the surfaces on which straight magnetic field line coordinates will be calculated. The use of high order periodic orbits has increase the robustness and speed of the PIES code. We now have more uniform treatment of in-phase and out-of-phase islands. This new version has better convergence properties and works well with a full Newton scheme. We now have the ability to shrink islands using a bootstrap like current and this includes the m=1 island in tokamaks.

49 CFR 40.361 - What is the purpose of a public interest exclusion (PIE)?

Code of Federal Regulations, 2010 CFR

2010-10-01

... transportation employers and employees from serious noncompliance with DOT drug and alcohol testing rules, the Department's policy is to ensure that employers conduct business only with responsible service agents. (b... alcohol testing regulations, has shown that it is not currently acting in a responsible manner. (c) A PIE...

49 CFR 40.375 - How does the initiating official start a PIE proceeding?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false How does the initiating official start a PIE... factual basis for the initiating official's belief that you are not providing drug and/or alcohol testing... belief that your noncompliance has not been or cannot be corrected; (4) The initiating official's...

49 CFR 40.375 - How does the initiating official start a PIE proceeding?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false How does the initiating official start a PIE... factual basis for the initiating official's belief that you are not providing drug and/or alcohol testing... belief that your noncompliance has not been or cannot be corrected; (4) The initiating official's...

49 CFR 40.375 - How does the initiating official start a PIE proceeding?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false How does the initiating official start a PIE... factual basis for the initiating official's belief that you are not providing drug and/or alcohol testing... belief that your noncompliance has not been or cannot be corrected; (4) The initiating official's...

49 CFR 40.375 - How does the initiating official start a PIE proceeding?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false How does the initiating official start a PIE... factual basis for the initiating official's belief that you are not providing drug and/or alcohol testing... belief that your noncompliance has not been or cannot be corrected; (4) The initiating official's...

49 CFR 40.375 - How does the initiating official start a PIE proceeding?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false How does the initiating official start a PIE... factual basis for the initiating official's belief that you are not providing drug and/or alcohol testing... belief that your noncompliance has not been or cannot be corrected; (4) The initiating official's...

Playful Invention and Exploration. Final Evaluation Report: Executive Summary

ERIC Educational Resources Information Center

St. John; Mark; Carroll, Becky; Helms, Jen; Smith, Anita

2008-01-01

PIE (Playful Invention and Exploration) is a unique approach to learning that centers on the use of technology and design challenges to create powerful learning experiences in informal education settings. The Playful Invention and Exploration (PIE) Institute project was funded in 2005 by the National Science Foundation (NSF). Overall, 150…

Two-Person Pie-Cutting: The Fairest Cuts

ERIC Educational Resources Information Center

Barbanel, Julius B.; Brams, Steven J.

2011-01-01

Barbanel, Brams, and Stromquist (in 2009) asked whether there exists a two-person moving-knife procedure that yields an envy-free, undominated, and equitable division of a pie. We present two procedures: One yields an envy-free, almost undominated, and almost equitable allocation, whereas the second yields an allocation with the two "almost"…

Children and Drug Education: The P.I.E.D. Pipers.

ERIC Educational Resources Information Center

Gloss, Elizabeth

1995-01-01

Developing coping skills for preventing substance abuse and promoting interaction and role modeling among older and younger children were the goals of the P.I.E.D. (People Involved in Education about Drugs) Pipers project. Nurses taught content to student trainees who presented information to peers and younger children. (SK)

"A New Kind of Rule": The Subversive Narrator in "Alice's Adventures in Wonderland" and "The Pied Piper of Hamelin."

ERIC Educational Resources Information Center

Blackburn, William

1986-01-01

Compares "Alice's Adventures in Wonderland" to "The Pied Piper of Hamelin," noting that both: (1) were begun for the amusement of specific children; (2) use a subterranean journey as a device; (3) are critical of social authority; and (4) have problematic endings. (SRT)

A New Dual-Frequency Liquid Crystal Lens with Ring-and-Pie Electrodes and a Driving Scheme to Prevent Disclination Lines and Improve Recovery Time

PubMed Central

Kao, Yung-Yuan; Chao, Paul C.-P.

2011-01-01

A new liquid crystal lens design is proposed to improve the recovery time with a ring-and-pie electrode pattern through a suitable driving scheme and using dual-frequency liquid crystals (DFLC) MLC-2048. Compared with the conventional single hole-type liquid crystal lens, this new structure of the DFLC lens is composed of only two ITO glasses, one of which is designed with the ring-and-pie pattern. For this device, one can control the orientation of liquid crystal directors via a three-stage switching procedure on the particularly-designed ring-and-pie electrode pattern. This aims to eliminate the disclination lines, and using different drive frequencies to reduce the recovery time to be less than 5 seconds. The proposed DFLC lens is shown effective in reducing recovery time, and then serves well as a potential device in places of the conventional lenses with fixed focus lengths and the conventional LC lens with a single circular-hole electrode pattern. PMID:22163906

Does food complexity have a role in eliciting expectations of satiating capacity?

PubMed

Marcano, Johanna; Morales, Diana; Vélez-Ruiz, Jorge F; Fiszman, Susana

2015-09-01

New strategies for formulating healthy, balanced food with enhanced expected satiating capacity are a hot topic. The present work tests the hypothesis that adding complexity to food will result in higher expectations of satiating capacity. Different kinds of "visible" particles (wheat bran, ground coconut, flaxseeds and oat meal) were added to cheese pies with the aim of increasing the complexity of both their appearance and their texture. Two more basic recipes were also prepared with no particles added. Instrumental texture measurements, complexity and expected satiating capacity consumer scoring and sensory profiling of the six pie formulations were performed. In addition, the consumers were asked to write down the characteristics they took into account in their pie complexity scores. For pies with very similar instrumental TPA hardness and resistance to penetration values, a clear trend that emerged was that the more complex the texture, the higher the satiating capacity expectations. The qualitative analysis of the terms mentioned by consumers was of great value for understanding the concepts underlying the appraisal of the samples' complexity. Copyright © 2015 Elsevier Ltd. All rights reserved.

PIE on Safety-Tested AGR-1 Compact 5-1-1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunn, John D.; Morris, Robert Noel; Baldwin, Charles A.

Post-irradiation examination (PIE) is being performed in support of tristructural isotropic (TRISO) coated particle fuel development and qualification for High-Temperature Gas-cooled Reactors (HTGRs). AGR-1 was the first in a series of TRISO fuel irradiation experiments initiated in 2006 under the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program; this work continues to be funded by the Department of Energy's Office of Nuclear Energy as part of the Advanced Reactor Technologies (ART) initiative. AGR-1 fuel compacts were fabricated at Oak Ridge National Laboratory (ORNL) in 2006 and irradiated for three years in the Idaho National Laboratory (INL) Advanced Test Reactormore » (ATR) to demonstrate and evaluate fuel performance under HTGR irradiation conditions. PIE is being performed at INL and ORNL to study how the fuel behaved during irradiation, and to examine fuel performance during exposure to elevated temperatures at or above temperatures that could occur during a depressurized conduction cooldown event. This report summarizes safety testing of irradiated AGR-1 Compact 5-1-1 in the ORNL Core Conduction Cooldown Test Facility (CCCTF) and post-safety testing PIE.« less

Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate.

PubMed

Toth, Krisztina; Amyes, Tina L; Wood, Bryant M; Chan, Kui; Gerlt, John A; Richard, John P

2010-05-26

A product deuterium isotope effect (PIE) of 1.0 was determined as the ratio of the yields of [6-(1)H]-uridine 5'-monophosphate (50%) and [6-(2)H]-uridine 5'-monophosphate (50%) from the decarboxylation of orotidine 5'-monophosphate (OMP) in 50/50 (v/v) HOH/DOD catalyzed by orotidine 5'-monophosphate decarboxylase (OMPDC) from Saccharomyces cerevisiae, Methanothermobacter thermautotrophicus, and Escherichia coli. This unitary PIE eliminates a proposed mechanism for enzyme-catalyzed decarboxylation in which proton transfer from Lys-93 to C-6 of OMP provides electrophilic push to the loss of CO(2) in a concerted reaction. We propose that the complete lack of selectivity for the reaction of solvent H and D, which is implied by the value of PIE = 1.0, is enforced by restricted C-N bond rotation of the -CH(2)-NL(3)(+) group of the side chain of Lys-93. A smaller PIE of 0.93 was determined as the ratio of the product yields for OMPDC-catalyzed decarboxylation of 5-fluoroorotidine 5'-monophosphate (5-FOMP) in 50/50 (v/v) HOH/DOD. Mutations on the following important active-site residues of OMPDC from S. cerevisiae have no effect on the PIE on OMPDC-catalyzed decarboxylation of OMP or decarboxylation of 5-FOMP: R235A, Y217A, Q215A, S124A, and S154A/Q215A.

Product Deuterium Isotope Effects for Orotidine 5'-Monophosphate Decarboxylase: Effect of Changing Substrate and Enzyme Structure on the Partitioning of the Vinyl Carbanion Reaction Intermediate

PubMed Central

Toth, Krisztina; Amyes, Tina L.; Wood, Bryant M.; Chan, Kui; Gerlt, John A.

2010-01-01

A product deuterium isotope effect (PIE) of 1.0 was determined as the ratio of the yields of [6-1H]-uridine 5'-monophosphate (50%) and [6-2H]-uridine 5'-monophosphate (50%) from the decarboxylation of orotidine 5'-monophosphate (OMP) in 50/50 (v/v) HOH/DOD catalyzed by orotidine 5'-monophosphate decarboxylase (OMPDC) from S. cerevisiae, M. thermautotrophicus and E. coli. This unitary PIE eliminates a proposed mechanism for enzyme-catalyzed decarboxylation in which proton transfer from Lys-93 to C-6 of OMP provides electrophilic push to the loss of CO2 in a concerted reaction. We propose that the complete lack of selectivity for the reaction of solvent H and D, that is implied by the value of PIE = 1.0, is enforced by restricted C-N bond rotation of the -CH2-NL3+ group of the side-chain of Lys-93. A smaller PIE of 0.93 was determined as the ratio of the product yields for OMPDC-catalyzed decarboxylation of 5-fluoroorotidine 5'-monophosphate (5-FOMP) in 50/50 (v/v) HOH/DOD. The following mutations of important active site residues of OMPDC from S. cerevisiae have no effect on the PIE on OMPDC-catalyzed decarboxylation of OMP or decarboxylation of 5-FOMP: R235A, Y217A, Q215A, S124A and S154A/Q215A. PMID:20441167

Ultra-high speed digital micro-mirror device based ptychographic iterative engine method

PubMed Central

Sun, Aihui; He, Xiaoliang; Kong, Yan; Cui, Haoyang; Song, Xiaojun; Xue, Liang; Wang, Shouyu; Liu, Cheng

2017-01-01

To reduce the long data acquisition time of the common mechanical scanning based Ptychographic Iterative Engine (PIE) technique, the digital micro-mirror device (DMD) is used to form the fast scanning illumination on the sample. Since the transverse mechanical scanning in the common PIE is replaced by the on/off switching of the micro-mirrors, the data acquisition time can be reduced from more than 15 minutes to less than 20 seconds for recording 12 × 10 diffraction patterns to cover the same field of 147.08 mm2. Furthermore, since the precision of DMD fabricated with the optical lithography is always higher than 10 nm (1 μm for the mechanical translation stage), the time consuming position-error-correction procedure is not required in the iterative reconstruction. These two improvements fundamentally speed up both the data acquisition and the reconstruction procedures in PIE, and relax its requirements on the stability of the imaging system, therefore remarkably improve its applicability for many practices. It is demonstrated experimentally with both USAF resolution target and biological sample that, the spatial resolution of 5.52 μm and the field of view of 147.08 mm2 can be reached with the DMD based PIE method. In a word, by using the DMD to replace the translation stage, we can effectively overcome the main shortcomings of common PIE related to the mechanical scanning, while keeping its advantages on both the high resolution and large field of view. PMID:28717560

Immunobiotic Lactobacillus jensenii Elicits Anti-Inflammatory Activity in Porcine Intestinal Epithelial Cells by Modulating Negative Regulators of the Toll-Like Receptor Signaling Pathway

PubMed Central

Shimazu, Tomoyuki; Villena, Julio; Tohno, Masanori; Fujie, Hitomi; Hosoya, Shoichi; Shimosato, Takeshi; Aso, Hisashi; Suda, Yoshihito; Kawai, Yasushi; Saito, Tadao; Makino, Seiya; Ikegami, Shuji; Itoh, Hiroyuki

2012-01-01

The effect of Lactobacillus jensenii TL2937 on the inflammatory immune response triggered by enterotoxigenic Escherichia coli (ETEC) and lipopolysaccharide (LPS) in a porcine intestinal epitheliocyte cell line (PIE cells) was evaluated. Challenges with ETEC or LPS elicited Toll-like receptor 4 (TLR4)-mediated inflammatory responses in cultured PIE cells, indicating that our cell line may be useful for studying inflammation in the guts of weaning piglets. In addition, we demonstrated that L. jensenii TL2937 attenuated the expression of proinflammatory cytokines and chemokines caused by ETEC or LPS challenge by downregulating TLR4-dependent nuclear factorκB (NF-κB) and mitogen-activated protein kinase (MAPK) activation. Furthermore, we demonstrated that L. jensenii TL2937 stimulation of PIE cells upregulated three negative regulators of TLRs: A20, Bcl-3, and MKP-1, deepening the understanding of an immunobiotic mechanism of action. L. jensenii TL2937-mediated induction of negative regulators of TLRs would have a substantial physiological impact on homeostasis in PIE cells, because excessive TLR inflammatory signaling would be downregulated. These results indicated that PIE cells can be used to study the mechanisms involved in the protective activity of immunobiotics against intestinal inflammatory damage and may provide useful information for the development of new immunologically functional feeds that help to prevent inflammatory intestinal disorders, including weaning-associated intestinal inflammation. PMID:22083706

Baking a mass-spectrometry data PIE with McMC and simulated annealing: predicting protein post-translational modifications from integrated top-down and bottom-up data.

PubMed

Jefferys, Stuart R; Giddings, Morgan C

2011-03-15

Post-translational modifications are vital to the function of proteins, but are hard to study, especially since several modified isoforms of a protein may be present simultaneously. Mass spectrometers are a great tool for investigating modified proteins, but the data they provide is often incomplete, ambiguous and difficult to interpret. Combining data from multiple experimental techniques-especially bottom-up and top-down mass spectrometry-provides complementary information. When integrated with background knowledge this allows a human expert to interpret what modifications are present and where on a protein they are located. However, the process is arduous and for high-throughput applications needs to be automated. This article explores a data integration methodology based on Markov chain Monte Carlo and simulated annealing. Our software, the Protein Inference Engine (the PIE) applies these algorithms using a modular approach, allowing multiple types of data to be considered simultaneously and for new data types to be added as needed. Even for complicated data representing multiple modifications and several isoforms, the PIE generates accurate modification predictions, including location. When applied to experimental data collected on the L7/L12 ribosomal protein the PIE was able to make predictions consistent with manual interpretation for several different L7/L12 isoforms using a combination of bottom-up data with experimentally identified intact masses. Software, demo projects and source can be downloaded from http://pie.giddingslab.org/

Information sought, information shared: exploring performance and image enhancing drug user-facilitated harm reduction information in online forums.

PubMed

Tighe, Boden; Dunn, Matthew; McKay, Fiona H; Piatkowski, Timothy

2017-07-21

There is good evidence to suggest that performance and image enhancing drug (PIED) use is increasing in Australia and that there is an increase in those using PIEDs who have never used another illicit substance. Peers have always been an important source of information in this group, though the rise of the Internet, and the increased use of Internet forums amongst substance consumers to share harm reduction information, means that PIED users may have access to a large array of views and opinions. The aim of this study was to explore the type of information that PIED users seek and share on these forums. An online search was conducted to identify online forums that discussed PIED use. Three discussion forums were included in this study: aussiegymjunkies.com, bodybuildingforums.com.au, and brotherhoodofpain.com. The primary source of data for this study was the 'threads' from the online forums. Threads were thematically analysed for overall content, leading to the identification of themes. One hundred thirty-four threads and 1716 individual posts from 450 unique avatars were included in this analysis. Two themes were identified: (1) personal experiences and advice and (2) referral to services and referral to the scientific literature. Internet forums are an accessible way for members of the PIED community to seek and share information to reduce the harms associated with PIED use. Forum members show concern for both their own and others' use and, where they lack information, will recommend seeking information from medical professionals. Anecdotal evidence is given high credence though the findings from the scientific literature are used to support opinions. The engagement of health professionals within forums could prove a useful strategy for engaging with this population to provide harm reduction interventions, particularly as forum members are clearly seeking further reliable information, and peers may act as a conduit between users and the health and medical profession.

Transcriptomic Analysis of the Innate Antiviral Immune Response in Porcine Intestinal Epithelial Cells: Influence of Immunobiotic Lactobacilli

PubMed Central

Albarracin, Leonardo; Kobayashi, Hisakazu; Iida, Hikaru; Sato, Nana; Nochi, Tomonori; Aso, Hisashi; Salva, Susana; Alvarez, Susana; Kitazawa, Haruki; Villena, Julio

2017-01-01

Lactobacillus rhamnosus CRL1505 and Lactobacillus plantarum CRL1506 are immunobiotic strains able to increase protection against viral intestinal infections as demonstrated in animal models and humans. To gain insight into the host–immunobiotic interaction, the transcriptomic response of porcine intestinal epithelial (PIE) cells to the challenge with viral molecular associated pattern poly(I:C) and the changes in the transcriptomic profile induced by the immunobiotics strains CRL1505 and CRL1506 were investigated in this work. By using microarray technology and reverse transcription PCR, we obtained a global overview of the immune genes involved in the innate antiviral immune response in PIE cells. Stimulation of PIE cells with poly(I:C) significantly increased the expression of IFN-α and IFN-β, several interferon-stimulated genes, cytokines, chemokines, adhesion molecules, and genes involved in prostaglandin biosynthesis. It was also determined that lactobacilli differently modulated immune gene expression in poly(I:C)-challenged PIE cells. Most notable changes were found in antiviral factors (IFN-α, IFN-β, NPLR3, OAS1, OASL, MX2, and RNASEL) and cytokines/chemokines (IL-1β, IL-6, CCL4, CCL5, and CXCL10) that were significantly increased in lactobacilli-treated PIE cells. Immunobiotics reduced the expression of IL-15 and RAE1 genes that mediate poly(I:C) inflammatory damage. In addition, lactobacilli treatments increased the expression PLA2G4A, PTGES, and PTGS2 that are involved in prostaglandin E2 biosynthesis. L. rhamnosus CRL1505 and L. plantarum CRL1506 showed quantitative and qualitative differences in their capacities to modulate the innate antiviral immune response in PIE cells, which would explain the higher capacity of the CRL1505 strain when compared to CRL1506 to protect against viral infection and inflammatory damage in vivo. These results provided valuable information for the deeper understanding of the host–immunobiotic interaction and their effect on antiviral immunity. The comprehensive transcriptomic analyses successfully identified a group of genes (IFN-β, RIG1, RNASEL, MX2, A20, IL27, CXCL5, CCL4, PTGES, and PTGER4), which can be used as prospective biomarkers for the screening of new antiviral immunobiotics in PIE cells and for the development of novel functional food and feeds, which may help to prevent viral infections. PMID:28210256

Transcriptomic Analysis of the Innate Antiviral Immune Response in Porcine Intestinal Epithelial Cells: Influence of Immunobiotic Lactobacilli.

PubMed

Albarracin, Leonardo; Kobayashi, Hisakazu; Iida, Hikaru; Sato, Nana; Nochi, Tomonori; Aso, Hisashi; Salva, Susana; Alvarez, Susana; Kitazawa, Haruki; Villena, Julio

2017-01-01

Lactobacillus rhamnosus CRL1505 and Lactobacillus plantarum CRL1506 are immunobiotic strains able to increase protection against viral intestinal infections as demonstrated in animal models and humans. To gain insight into the host-immunobiotic interaction, the transcriptomic response of porcine intestinal epithelial (PIE) cells to the challenge with viral molecular associated pattern poly(I:C) and the changes in the transcriptomic profile induced by the immunobiotics strains CRL1505 and CRL1506 were investigated in this work. By using microarray technology and reverse transcription PCR, we obtained a global overview of the immune genes involved in the innate antiviral immune response in PIE cells. Stimulation of PIE cells with poly(I:C) significantly increased the expression of IFN- α and IFN- β, several interferon-stimulated genes, cytokines, chemokines, adhesion molecules, and genes involved in prostaglandin biosynthesis. It was also determined that lactobacilli differently modulated immune gene expression in poly(I:C)-challenged PIE cells. Most notable changes were found in antiviral factors ( IFN- α, IFN- β, NPLR3, OAS1, OASL, MX2 , and RNASEL ) and cytokines/chemokines ( IL-1 β, IL-6, CCL4, CCL5 , and CXCL10 ) that were significantly increased in lactobacilli-treated PIE cells. Immunobiotics reduced the expression of IL-15 and RAE1 genes that mediate poly(I:C) inflammatory damage. In addition, lactobacilli treatments increased the expression PLA2G4A, PTGES , and PTGS2 that are involved in prostaglandin E2 biosynthesis . L. rhamnosus CRL1505 and L. plantarum CRL1506 showed quantitative and qualitative differences in their capacities to modulate the innate antiviral immune response in PIE cells, which would explain the higher capacity of the CRL1505 strain when compared to CRL1506 to protect against viral infection and inflammatory damage in vivo . These results provided valuable information for the deeper understanding of the host-immunobiotic interaction and their effect on antiviral immunity. The comprehensive transcriptomic analyses successfully identified a group of genes ( IFN- β, RIG1, RNASEL, MX2, A20, IL27, CXCL5, CCL4, PTGES , and PTGER4 ), which can be used as prospective biomarkers for the screening of new antiviral immunobiotics in PIE cells and for the development of novel functional food and feeds, which may help to prevent viral infections.

Mnemonic Device for Relating the Eight Thermodynamic State Variables: The Energy Pie

ERIC Educational Resources Information Center

Fieberg, Jeffrey E.; Girard, Charles A.

2011-01-01

A mnemonic device, the energy pie, is presented that provides relationships between thermodynamic potentials ("U," "H," "G," and "A") and other sets of variables that carry energy units, "TS" and "PV." Methods are also presented in which the differential expressions for the potentials and the corresponding Maxwell relations follow from the energy…

Mineral of the month: boron

USGS Publications Warehouse

Lyday, Phyllis A.

2005-01-01

What does boron have to do with baseball, apple pie, motherhood and Chevrolet? Boron minerals and chemicals are used in the tanning of leather baseballs and gloves; in micro-fertilizer to grow apples and in the glass and enamels of bakewares to cook apple pie; in boron detergents for soaking baby clothes and diapers; and in fiberglass parts for the Chevrolet Corvette.

The Psychosocial Inventory of Ego Strengths: Examination of Theory and Psychometric Properties

ERIC Educational Resources Information Center

Markstrom, Carol A.; Marshall, Sheila K.

2007-01-01

The psychosocial inventory of ego strengths (PIES) was devised as a measure of Erikson's eight ego strengths. The present investigation extended previous research through examination of the validity and reliability of the PIES among 502 high school students. The study also included an appraisal of Erikson's ego strengths as indices of psychosocial…

Learning Cities as Healthy Green Cities: Building Sustainable Opportunity Cities

ERIC Educational Resources Information Center

Kearns, Peter

2012-01-01

This paper discusses a new generation of learning cities we have called EcCoWell cities (Economy, Community, Well-being). The paper was prepared for the PASCAL International Exchanges (PIE) and is based on international experiences with PIE and developments in some cities. The paper argues for more holistic and integrated development so that…

Lifting the Curse of the Roman: Quintus Horatius Flaccus Meets the Pied Piper of Hamelin.

ERIC Educational Resources Information Center

Blackburn, William

There are many similarities between Robert Browning's "The Pied Piper of Hamelin" and Lewis Carroll's "Alice in Wonderland" that are seldom noted by literary critics. Both works were begun for the amusement of specific children, both employ a strange subterranean journey as a central device, and both are works of nonsense…

Bars, Lines, & Pies: A Graphing Skills Program. Expect the Unexpected with Math[R

ERIC Educational Resources Information Center

Actuarial Foundation, 2013

2013-01-01

"Bars, Lines, & Pies" is a dynamic math program designed to build graphing skills in students, while also showing them the relevance of math in their lives. Developed by The Actuarial Foundation along with Scholastic, the graphing lessons and activities involve engaging, real-world examples about the environment and recycling. In these lessons,…

Obtaining Employment after Spinal Cord Injury: Relationship with Pre- and Postinjury Education

ERIC Educational Resources Information Center

Krause, James S.; Reed, Karla S.

2009-01-01

The authors identify the association of educational milestones obtained before and after spinal cord injury (SCI) with postinjury employment (PIE). Survey data were collected from 1,362 adults younger than 65, with traumatic SCI of at least 1 year duration who were not currently attending school. The sole outcome was obtaining PIE--whether the…

From Person-in-Environment to Strengths: The Promise of Postmodern Practice

ERIC Educational Resources Information Center

Dybicz, Phillip

2015-01-01

Social work relies heavily on its value base to guide practice; however, there are no conceptual models--on par with person-in-environment (PIE)--to describe how these values are implemented within an evidence-based approach. However, the philosophical foundation of empiricism and positivism that lends PIE its strength also brings with it inherent…

The percutaneous pie-crusting medial release during arthroscopic procedures of the medial meniscus does neither affect valgus laxity nor clinical outcome.

PubMed

Jeon, Sang-Woo; Jung, Min; Chun, Yong-Min; Lee, Su-Keon; Jung, Woo Seok; Choi, Chong Hyuk; Kim, Sung-Jae; Kim, Sung-Hwan

2017-12-28

To analyze the effect of percutaneous pie-crusting medial release on valgus laxity before and after surgery and on clinical outcomes. Eight-hundred fourteen consecutive patients who underwent an arthroscopic procedure for the medial compartment of the knee were evaluated retrospectively. Sex, age, type of operation (meniscectomy, meniscal repair, and posterior root repair), type of accompanying surgery (none, cartilage procedure, ligament procedure and osteotomy) were documented. Sixty-four patients who underwent percutaneous pie-crusting medial release (release group) and 64 who did not undergo medial release (non-release group) were matched using the propensity score method. Each patient was evaluated for the following variables: degree of valgus laxity on stress radiographs, Lysholm knee score, visual analog scale score, and International Knee Documentation Committee knee score and grade. At the 24-month follow-up, no significant increase in side-to-side differences in the valgus gap was observed in comparison to the preoperative value in the release group [preoperative, - 0.1 ± 1.3 mm; follow-up, - 0.1 ± 1.4 mm; (n.s.)]. The follow-up Lysholm score, visual analog scale score and International Knee Documentation Committee knee score and grade were similar between the two groups. Percutaneous pie-crusting medial release is an additional procedure that can be performed during arthroscopic surgery for patients with a narrow medial joint space of the knee. Percutaneous pie-crusting medial release reduces iatrogenic injury to the cartilage and does not produce any residual valgus laxity of the knee. IV.

Steeling the Mind. Combat Stress Reactions and Their Implications for Urban Warfare

DTIC Science & Technology

2004-01-01

65 Contents vii CHAPTER FIVE Reversing the Tide: Treatment Principles for Battle Fatigue ............ 69 Sym ptom s and D iagnosis...Same Principles Still Apply ............ 80 Urban-Specific Applications .............................................. 84 T he Success of PIES...PIES) was subsequently coined to summarize these principles . Forgetful of French, British, and American hard-earned lessons, the U.S. military in

Reading: Making It Personal Again--Now Serving PIE to Hungry Readers

ERIC Educational Resources Information Center

Hobbs, Nancy; Oleynik, Myra; Sacco, Kristen

2009-01-01

Something wonderful happens when children are asked to choose their own books and are given ample time to read and discuss them. They become hungry readers with an appetite for books! This simple strategy was the basis for developing the program known as PIE (Personalized Independent Enrichment) and its recipe for reading success. The goal of the…

21 CFR 152.126 - Frozen cherry pie.

Code of Federal Regulations, 2013 CFR

2013-04-01

... additives as defined in section 201(s) of the Federal Food, Drug, and Cosmetic Act or color additives as defined in section 201(t) of the act; or if they are food additives or color additives as so defined, they... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Frozen cherry pie. 152.126 Section 152.126 Food...

21 CFR 152.126 - Frozen cherry pie.

Code of Federal Regulations, 2014 CFR

2014-04-01

... additives as defined in section 201(s) of the Federal Food, Drug, and Cosmetic Act or color additives as defined in section 201(t) of the act; or if they are food additives or color additives as so defined, they... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Frozen cherry pie. 152.126 Section 152.126 Food...

21 CFR 152.126 - Frozen cherry pie.

Code of Federal Regulations, 2012 CFR

2012-04-01

... additives as defined in section 201(s) of the Federal Food, Drug, and Cosmetic Act or color additives as defined in section 201(t) of the act; or if they are food additives or color additives as so defined, they... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Frozen cherry pie. 152.126 Section 152.126 Food...

Mineral resource of the month: boron

USGS Publications Warehouse

Lyday, Phyllis A.

2005-01-01

What does boron have to do with baseball, apple pie, motherhood and Chevrolet? Boron minerals and chemicals are used in the tanning of leather baseballs and gloves; in micro-fertilizer to grow apples and in the glass and enamels of bakewares to cook apple pie; in boron detergents for soaking baby clothes and diapers; and in fiberglass parts for the Chevrolet Corvette.

Functional Analysis and Treatment of Rumination Using Fixed-Time Delivery of a Flavor Spray

ERIC Educational Resources Information Center

Wilder, David A.; Register, Martisa; Register, Stanley; Bajagic, Vedrana; Neidert, Pamela L.

2009-01-01

A functional analysis suggested that rumination exhibited by an adult with autism was maintained by automatic reinforcement. Next, a preference assessment with three flavor sprays (i.e., flavored sprays used by dieters) showed that apple pie spray was most preferred. Finally, the effects of fixed-time delivery of the apple pie spray on levels of…

21 CFR 152.126 - Frozen cherry pie.

Code of Federal Regulations, 2011 CFR

2011-04-01

... additives as defined in section 201(s) of the Federal Food, Drug, and Cosmetic Act or color additives as defined in section 201(t) of the act; or if they are food additives or color additives as so defined, they... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Frozen cherry pie. 152.126 Section 152.126 Food...

21 CFR 152.126 - Frozen cherry pie.

Code of Federal Regulations, 2010 CFR

2010-04-01

... additives as defined in section 201(s) of the Federal Food, Drug, and Cosmetic Act or color additives as defined in section 201(t) of the act; or if they are food additives or color additives as so defined, they... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Frozen cherry pie. 152.126 Section 152.126 Food...

A Comparison of Learning Management Systems in a School District: Searching for the Ideal Personalized Integrated Educational System (PIES)

ERIC Educational Resources Information Center

Yildirim, Zahide; Reigeluth, Charles M.; Kwon, Seolim; Kageto, Yuichi; Shao, Zihang

2014-01-01

This study explored the use of several learning management systems (LMS), their benefits, and their limitations in relation to the desired characteristics of an ideal Personalized Integrated Educational System (PIES) for the information age. A qualitative research design was used. The participants of the study were teachers, administrators, and…

The Production System's Formulation of Relative Clause Structures: Evidence from Polish

ERIC Educational Resources Information Center

McDaniel, Dana; Lech, Dorota

2003-01-01

In this study, we focused on the formulation of relative clauses with preposition and genitive pied-piping. Thirty child (5;9 to 8;4) and 30 adult Polish speakers were given an elicited production task and a grammaticality judgment task. Almost all of the children accepted preposition pied-piping, but only half of them produced it. We suggest that…

Giant Paperclip Necklaces, Soup-Can Rings and Cherry-Pie Hats

ERIC Educational Resources Information Center

Winters, Laurel A.

2011-01-01

In this article, the author describes an art project inspired by the wearable sculpture art created by artist Marjorie Schick. Students used wallpaper paste and newspapers to create papier-mache for a mountain hat, a cherry-pie mask/hat, a "dress" shoe and a Cubistic mask. Cardboard was used in many of these things, in addition to being used as…

Design Parameters and Objectives of a High-­Resolution X-­ray Imaging Crystal Spectrometer for the Large Helical Device (LHD)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bitter, M; Gates, D; Neilson, H

A high-resolution X-ray imaging crystal spectrometer, whose instrumental concept was thoroughly tested on NSTX and Alcator C-Mod, is presently being designed for LHD. The instrument will record spatially resolved spectra of helium-like Ar16+ and provide ion temperature profiles with spatial and temporal resolutions of 1 cm and > 10 ms which are obtained by a tomographic inversion of the spectral data, using the stellarator equilibrium reconstruction codes, STELLOPT and PIES. Since the spectrometer will be equipped with radiation hardened, high count rate, PILATUS detectors,, it is expected to be operational for all experimental conditions on LHD, which include plasmas ofmore » high density and plasmas with auxiliary RF and neutral beam heating. The special design features required by the magnetic field structure at LHD will be described.« less

A vacuum ultraviolet photoionization study on the thermal decomposition of ammonium perchlorate

DOE PAGES

Gobi, Sandor; Zhao, Long; Xu, Bo; ...

2017-11-14

Pyrolysis products of ammonium perchlorate (NH 4ClO 4) at 483 K were monitored on line and in situ via single photon photoionization reflectron time-of-flight spectrometry (PI-ReTOF-MS) in the photon energy range of 9.00–17.50 eV. The photoionization efficiency curves (PIE) of the subliming product molecules were collected and allowed for detection of three class of products containing chlorine, nitrogen, and oxygen including atoms and free radicals. The results found suggest a new insight into possible low-temperature decomposition pathways of NH 4ClO 4.

A vacuum ultraviolet photoionization study on the thermal decomposition of ammonium perchlorate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gobi, Sandor; Zhao, Long; Xu, Bo

Pyrolysis products of ammonium perchlorate (NH 4ClO 4) at 483 K were monitored on line and in situ via single photon photoionization reflectron time-of-flight spectrometry (PI-ReTOF-MS) in the photon energy range of 9.00–17.50 eV. The photoionization efficiency curves (PIE) of the subliming product molecules were collected and allowed for detection of three class of products containing chlorine, nitrogen, and oxygen including atoms and free radicals. The results found suggest a new insight into possible low-temperature decomposition pathways of NH 4ClO 4.

A vacuum ultraviolet photoionization study on the thermal decomposition of ammonium perchlorate

NASA Astrophysics Data System (ADS)

Góbi, Sándor; Zhao, Long; Xu, Bo; Ablikim, Utuq; Ahmed, Musahid; Kaiser, Ralf I.

2018-01-01

Pyrolysis products of ammonium perchlorate (NH4ClO4) at 483 K were monitored on line and in situ via single photon photoionization reflectron time-of-flight spectrometry (PI-ReTOF-MS) in the photon energy range of 9.00-17.50 eV. The photoionization efficiency curves (PIE) of the subliming product molecules were collected and allowed for detection of three class of products containing chlorine, nitrogen, and oxygen including atoms and free radicals. These results suggest a new insight into possible low-temperature decomposition pathways of NH4ClO4.

Fracto-emission from graphite/epoxy composites

NASA Technical Reports Server (NTRS)

Dickinson, J. T.

1983-01-01

Fracto-emission (FE) is the emission of particles and photons during and following crack propagation. Electrons (EE), positive ions (PIE), and excited and ground state neutrals (NE) were observed. Results of a number of experiments involving principally graphite/epoxy composites and Kevlar single fibers are presented. The physical processes responsible for EE and PIE are discussed as well as FE from fiber- and particulate-reinforced composites.

Using Discrete Trial Training to Identify Specific Learning Impairments in Boys with Fragile X Syndrome

ERIC Educational Resources Information Center

Hall, Scott S.; Hustyi, Kristin M.; Hammond, Jennifer L.; Hirt, Melissa; Reiss, Allan L.

2014-01-01

We examined whether "discrete trial training" (DTT) could be used to identify learning impairments in mathematical reasoning in boys with fragile X syndrome (FXS). Boys with FXS, aged 10-23 years, and age and IQ-matched controls, were trained to match fractions to pie-charts and pie-charts to decimals either on a computer or with a…

Navy Nutrition and Weight Control Guide

DTIC Science & Technology

1989-04-10

honey, syrup, jam, jelly, many desserts (pie, cake, cookies ), COMPLEX - Starches, vegetables, dried beans, whole grains, breads, cereals, pasta, foods...whole-grain flour for half the amount of white flour when you bake quick breads or cookies : bran muffins, cornbread, from whole, ground cornmeal...soft drinks, sweetened fruit drinks, punches or ades? (bug juice) 2. Choose sweet desserts and snacks? (cakes, pies, cookies , and, ice cream) 3. Use

Immunobiotic Lactobacillus jensenii as immune-health promoting factor to improve growth performance and productivity in post-weaning pigs.

PubMed

Suda, Yoshihito; Villena, Julio; Takahashi, Yu; Hosoya, Shoichi; Tomosada, Yohsuke; Tsukida, Kohichiro; Shimazu, Tomoyuki; Aso, Hisashi; Tohno, Masanori; Ishida, Mitsuharu; Makino, Seiya; Ikegami, Shuji; Kitazawa, Haruki

2014-06-19

Immunoregulatory probiotics (immunobiotics) have been proposed to improve piglets' immune system to avoid intestinal infections and reduce unproductive inflammation after weaning. Previously, it was demonstrated that Lactobacillus jensenii TL2937 (LjTL2937) attenuated the inflammatory response triggered by activation of Toll-like receptor 4 (TLR-4) in porcine intestinal epithelial (PIE) cells and antigen presenting cells (APCs) from porcine Peyer's patches (PP). In view of the critical importance of PIE-APCs interactions in the regulation of intestinal immune responses, we aimed to examine the effect of LjTL2937 on activation patterns of APCs from swine PPs in co-cultures with PIE cells. In addition, we investigated whether LjTL2937 was able to beneficially modulate intestinal immunity of piglets after weaning to improve immune-health status. Stimulation of PIE-APCs co-cultures with LjTL2937 increased the expression of MHC-II, CD80/86, IL-10, and Bcl-3 in CD172a+CD11R1- and CD172a+CD11R1high APCs. In addition, the TL2937 strain caused the upregulation of three negative regulators of TLR4 in PIE cells: MKP-1, Bcl-3 and A20. These changes significantly reduced the inflammatory response triggered by TLR4 activation in PIE-APCs co-cultures. The in vivo experiments using castrated male piglets (crossbreeding (LWD) with Landrace (L), Large Yorkshire (W) and Duroc (D))of 3 weeks of age demonstrated that feeding with LjTL2937 significantly reduced blood complement activity and C reactive protein concentrations while no changes were observed in blood leukocytes, ratio of granulocytes to lymphocyte numbers, macrophages' activity and antibody levels. In addition, treatment with LjTL2937 significantly improved growth performance and productivity, and increased carcass quality. We demonstrated that the use of immunobiotics strains like LjTL2937, as supplemental additives for piglets feedings, could be used as a strategy to maintain and improve intestinal homeostasis; that is important for the development of the pig and for health and performance throughout the productive life of the animal.

Immunobiotic Lactobacillus jensenii as immune-health promoting factor to improve growth performance and productivity in post-weaning pigs

PubMed Central

2014-01-01

Background Immunoregulatory probiotics (immunobiotics) have been proposed to improve piglets’ immune system to avoid intestinal infections and reduce unproductive inflammation after weaning. Previously, it was demonstrated that Lactobacillus jensenii TL2937 (LjTL2937) attenuated the inflammatory response triggered by activation of Toll-like receptor 4 (TLR-4) in porcine intestinal epithelial (PIE) cells and antigen presenting cells (APCs) from porcine Peyer’s patches (PP). Objective In view of the critical importance of PIE-APCs interactions in the regulation of intestinal immune responses, we aimed to examine the effect of LjTL2937 on activation patterns of APCs from swine PPs in co-cultures with PIE cells. In addition, we investigated whether LjTL2937 was able to beneficially modulate intestinal immunity of piglets after weaning to improve immune-health status. Results Stimulation of PIE-APCs co-cultures with LjTL2937 increased the expression of MHC-II, CD80/86, IL-10, and Bcl-3 in CD172a+CD11R1- and CD172a+CD11R1high APCs. In addition, the TL2937 strain caused the upregulation of three negative regulators of TLR4 in PIE cells: MKP-1, Bcl-3 and A20. These changes significantly reduced the inflammatory response triggered by TLR4 activation in PIE-APCs co-cultures. The in vivo experiments using castrated male piglets (crossbreeding (LWD) with Landrace (L), Large Yorkshire (W) and Duroc (D))of 3 weeks of age demonstrated that feeding with LjTL2937 significantly reduced blood complement activity and C reactive protein concentrations while no changes were observed in blood leukocytes, ratio of granulocytes to lymphocyte numbers, macrophages’ activity and antibody levels. In addition, treatment with LjTL2937 significantly improved growth performance and productivity, and increased carcass quality. Conclusions We demonstrated that the use of immunobiotics strains like LjTL2937, as supplemental additives for piglets feedings, could be used as a strategy to maintain and improve intestinal homeostasis; that is important for the development of the pig and for health and performance throughout the productive life of the animal. PMID:24943108

Multi-species call-broadcast improved detection of endangered Yuma clapper rail compared to single-species call-broadcast

USGS Publications Warehouse

Nadeau, Christopher P.; Conway, Courtney J.; Piest, Linden; Burger, William P.

2013-01-01

Broadcasting calls of marsh birds during point-count surveys increases their detection probability and decreases variation in the number of birds detected across replicate surveys. However, multi-species monitoring using call-broadcast may reduce these benefits if birds are reluctant to call once they hear broadcasted calls of other species. We compared a protocol that uses call-broadcast for only one species (Yuma clapper rail [Rallus longirostris yumanensis]) to a protocol that uses call-broadcast for multiple species. We detected more of each of the following species using the multi-species protocol: 25 % more pied-billed grebes, 160 % more American bitterns, 52 % more least bitterns, 388 % more California black rails, 12 % more Yuma clapper rails, 156 % more Virginia rails, 214 % more soras, and 19 % more common gallinules. Moreover, the coefficient of variation was smaller when using the multi-species protocol: 10 % smaller for pied-billed grebes, 38 % smaller for American bitterns, 19 % smaller for least bitterns, 55 % smaller for California black rails, 5 % smaller for Yuma clapper rails, 38 % smaller for Virginia rails, 44 % smaller for soras, and 8 % smaller for common gallinules. Our results suggest that multi-species monitoring approaches may be more effective and more efficient than single-species approaches even when using call-broadcast.

[Characterization and nutritional value of a food artisan: the meat pie of Murcia].

PubMed

Ruiz-Cano, Domingo; Pérez-Llamas, Francisca; López-Jiménez, José Ángel; González-Silvera, Daniel; Frutos, Maria José; Zamora, Salvador

2013-01-01

The main aims of this study are to describe the characteristics of the meat pie, a typical product of the regional gastronomy of Murcia and to determine its nutritional and energy values, fatty acid profile and fat quality. There were studied 24 samples of Murcia's meat pie from the six best-selling retail establishments in this Region (four units per establishment).The moisture, protein, fat, carbohydrates, fibre and minerals, contents and the energy value, fatty acid profile and fat quality were analyzed using the Official Analysis Methods of Foods. All analyses were performed by triplicate. The average weight of this product was 192.3 ± 11.8 g, with three differentiated parts (base, filling and pastry lid). All ingredients were natural raw materials: wheat flour, lard, ground beef, sliced boiled egg and chorizo, water and spices (salt, pepper, garlic, paprika and nutmeg). Most of its organoleptic attributes are due to the type and amount of fat or lard. The combination of the other ingredients and the particular formulation of the spices are also responsible of other attributes. Due to its protein content (11.0%), this meat pie can replace other meat dishes, and be incorporated into a balanced diet. However, it is necessary to take into account its fat and energy contents (17.3 g and 317 kcal/100 g, respectively). Unlike many common pastry products, it contains no trans fatty acids. The results of the research show that the studied product remains, at present, an artisan food, and offer reliable information that it is representative of the energy and nutritional values of the Murcia's meat pie, a typical product of the gastronomy of the Region of Murcia. Copyright © AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.

People into Employment: supporting people with disabilities and carers into work.

PubMed

Arksey, Hilary

2003-05-01

Carers and people with disabilities are two disadvantaged groups at risk of social exclusion. Work is an important route to social inclusion, but carers and people with disabilities are under-represented in the work force. The present paper reports key findings from a new study that evaluated People into Employment (PIE), a pilot employment project in the north-east of England designed to support people with disabilities, carers and former carers in gaining mainstream work. The study aimed to identify what clients, partner agencies and employers perceived to be PIE's most important services, its strengths and areas where there was scope for further development. The study collected quantitative and qualitative data at the mid-point and at the end of the project through two questionnaire surveys, and interviews with PIE clients, the project development officer, partner agencies and employers. Drawing on the 'pathway model', the findings show that PIE's interventions included mobilising, matching, mediating and supporting activities. Key ingredients in PIE's success include: tailor-made job-search activities and training; adjusting the pace at which people move towards sustained employment; recognising and responding to the differing needs of people with disabilities, carers and former carers; confidence boosting; accompanying clients to job interviews; good job matching; and ongoing practical and emotional support for both clients and employers. Rudimentary calculations suggest that the cost per job to the project is less than the cost per job for large national projects. Overall, these findings illustrate how access to employment via flexible job-search services geared up to the local labour market can successfully promote social inclusion for carers and people with disabilities.

Ultra-fast quantitative imaging using ptychographic iterative engine based digital micro-mirror device

NASA Astrophysics Data System (ADS)

Sun, Aihui; Tian, Xiaolin; Kong, Yan; Jiang, Zhilong; Liu, Fei; Xue, Liang; Wang, Shouyu; Liu, Cheng

2018-01-01

As a lensfree imaging technique, ptychographic iterative engine (PIE) method can provide both quantitative sample amplitude and phase distributions avoiding aberration. However, it requires field of view (FoV) scanning often relying on mechanical translation, which not only slows down measuring speed, but also introduces mechanical errors decreasing both resolution and accuracy in retrieved information. In order to achieve high-accurate quantitative imaging with fast speed, digital micromirror device (DMD) is adopted in PIE for large FoV scanning controlled by on/off state coding by DMD. Measurements were implemented using biological samples as well as USAF resolution target, proving high resolution in quantitative imaging using the proposed system. Considering its fast and accurate imaging capability, it is believed the DMD based PIE technique provides a potential solution for medical observation and measurements.

Chiral Dynamics 2006

NASA Astrophysics Data System (ADS)

Ahmed, Mohammad W.; Gao, Haiyan; Weller, Henry R.; Holstein, Barry

2007-10-01

pt. A. Plenary session. Opening remarks: experimental tests of chiral symmetry breaking / A. M. Bernstein. [Double pie symbols] scattering / H. Leutwyler. Chiral effective field theory in a [Triangle]-resonance region / V. Pascalutsa. Some recent developments in chiral perturbation theory / Ulf-G. Mei ner. Chiral extrapolation and nucleon structure from the lattice / R.D. Young. Recent results from HAPPEX / R. Michaels. Chiral symmetries and low energy searches for new physics / M.J. Ramsey-Musolf. Kaon physics: recent experimental progress / M. Moulson. Status of the Cabibbo angle / V. Cirigliano. Lattice QCD and nucleon spin structure / J.W. Negele. Spin sum rules and polarizabilities: results from Jefferson lab / J-P Chen. Compton scattering and nucleon polarisabilities / Judith A. McGovern. Virtual compton scattering at MIT-bates / R. Miskimen. Physics results from the BLAST detector at the BATES accelerator / R.P. Redwine. The [Pie sympbol]NN system, recent progress / C. Hanhart. Application of chiral nuclear forces to light nuclei / A. Nogga. New results on few-body experiments at low energy / Y. Nagai. Few-body lattice calculations / M.J. Savage. Research opportunities at the upgraded HI?S facility / H.R. Weller -- pt. B. Goldstone boson dynamics. Working group summary: Goldstone Boson dynamics / G. Colangelo and S. Giovannella. Recent results on radiative Kaon decays from NA48 and NA48/2 / S.G. López. Cusps in K-->3 [Pie symbol] decays / B. Kubis. Recent KTeV results on radiative Kaon decays / M.C. Ronquest. The [Double pie symbols] scattering amplitude / J.R. Peláez. Determination of the Regge parameters in the [Double pie symbols] scattering amplitude / I. Caprini. e+e- Hadronic cross section measurement at DA[symbol]NE with the KLOE detector / P. Beltrame. Measurement of the form factors of e+e- -->2([Pie symbol]+[Pie symbol]-), pp and the resonant parameters of the heavy charmonia at BES / H. Hu. Measurement of e+e- multihadronic cross section below 4.5 GeV with BABAR / A. Denig. The pion vector form-factor and (g-2)u / C. Smith. Partially quenched CHPT results to two loops / J. Bijnens. Pion-pion scattering with mixed action lattice QCD / P.F. Bedaque. Meson systems with Ginsparg-Wilson valence quarks / A. Walker-Loud. Low energy constants from the MILC collaboration / C. Bernard. Finite volume effects: lattice meets CHPT / G. Schierholz. Lattice QCD simulations with two light dynamical (Wilson) quarks / L. Giusti. Do we understand the low-energy constant L8? / M. Golterman. Quark mass dependence of LECs in the two-flavour sector / M. Schmid. Progress report on the [Pie symbol]0 Lifetime experiment (PRIMEX) at Jlab / D.E. McNulty. Determination of the charged pion polarizabilities / L.V. Fil'kov. Proposed measurement of electroproduction of [Pie symbol]0 near threshold using a large acceptance spectrometer / R.A. Lindgren. The [Pie symbol] meson in [Pie symbol]K scattering / B. Moussallam. Strangeness -1 Meson-Baryon scattering S-wave / J.A. Oller. Results on light mesons decays and dynamics at KLOE / M. Martini. Studies of decays of [symbol] and [symbol] mesons with WASA detector / A. Kupsc. Heavy Quark-Diquark symmetry and X PT for doubly heavy baryons / T. Mehen. HHChPT applied to the charmed-strange parity partners/ R.P. Springer. Study of pion structure through precise measurements of the [Pie symbol]+ --> e+[symbol] decay / D. Pocanic. Exceptional and non-exceptional contributions to the radiative [Pie symbol] decay / V. Mateu. Leading chiral logarithms from unitarity, analyticity and the Roy equations / A. Fuhrer. All orders symmetric subtraction of the nonlinear sigma model in D=4 / A. Quadri -- pt. C. Chiral dynamics in few-nucleon systems. Working group summary: chiral dynamics in few-nucleon systems / H.W Hammer, N. Kalantar-Nayestanaki, and D.R. Phillips. Power counting in nuclear chiral effective field theory / U. van Kolck. On the consistency of Weinberg's power counting / U-G Mei ner. Renormalization of singular potentials and power counting / M.P. Valderrrama. The challenge of calculating Baryon-Baryon scattering from lattice QCD / S.R. Beane. Precise absolute np scattering cross section and the charged [Pie symbol] NN coupling constant / S. E. Vigdor. Probing hadronic parity violation using few nucleon systems / S.A. Page. Extracting the neutron-neutron scattering length from neutron-deuteron breakup / C.R. Howell. Extraction of [equationl] from [Pie symbol]-d --> [equation] / A. Grudestig. The three- and four-body system with large scattering length / L. Platter. 3N and 4N systems and the Ay puzzle / T. Clegg. Recent progress in nuclear lattice simulations with effective field theory / D. Lee. Few-body studies at KVI / J.G. Messchendorp. Results of three nucleon experiments from RIKEN / K. Sekiguchi. A new opportunity to measure the total photoabsorption cross section of helium / P. T. Debevec. Three-body photodisintegration of 3He with double polarizations / X. Zong. Large two-pion exchange contributions to the pp --> pp[Pie symbol]0 reaction / F. Myhrer. Towards a systematic theory of nuclear forces / E. Epelbaum. Ab initio calculations of eletromagnetic reactions in light nuclei / W. Leidemann. Electron scattering from a polarized deuterium target at BLAST / R. Fatemi. Neutron-neutron scattering length from the reaction [equation] / V. Lensky. Renormalization group analysis of nuclear current operators / S.X. Nakamura. Recent results and future plans at MAX-LAB / K.G. Fissum. Nucleon polarizabilities from deutron compton scattering, and its lessons for chiral power counting / H. W. Grie hammer. Compton scattering on HE-3 / D. Choudhury -- pt. D. Hadron structure and Meson-Baryon interactions. Summary of the working group on Hadron structure and Meson-Baryon interactions / G. Feldman and T.R. Hemmert. Finite volume effects: lattice meets CHPT / G. Schierholz. Lattice discretization errors in chiral effective field theories / B.C. Tiburzi. SU(3)-breaking effects in hyperon semileptonic decays from lattice QCD / S. Simula. Uncertainty bands for chiral extrapolations / B.U. Musch. Update of the nucleon electromagnetic form factors / C. B. Crawford. N and N to ? transition from factors from lattice QCD / C. Alexandrou. The [equation] transition at low Q2 and the pionic contribution / S. Stave. Strange Quark CoNtributions to the form factors of the nucleon / F. Benmokhtar. Dynamical polarizabilities of the nucleon / B. Pasquini. Hadron magnetic moments and polarizabilities in lattice QCD / F.X. Lee. Spin-dependent compton scattering from 3He and the neutron spin polarizabilities / H. Gao. Chiral dynamics from Dyson-Schwinger equations / C.D. Roberts. Radiative neutron [Beta symbol]-decay in effective field theory / S. Gardner. Comparison between different renormalization schemes for co-variant BChPT / T.A. Gail. Non-perturbative study of the light pseudoscalar masses in chiral dynamics / José Antonio Oller. Masses and widths of hadrons in nuclear matter / M. Kotulla. Chiral effective field theory at finite density / R.J. Furnstahl. The K-nuclear interaction: a search fro deeply bound K-nuclear clusters / P. Camerini. Moments of GPDs from lattice QCD / D.G. Richards. Generalized parton distributions in effective field theory / J.W. Chen. Near-threshold pion production: experimental update / M.W. Ahmed. Pion photoproduction near threshold theory update / L. Tiator.

A System for the Preference Evaluation of Cycle Menus

DTIC Science & Technology

1974-10-01

Potatoes, Okra, Jellied Fruit Salad, Peach Shortcake 27. Swedish Meatballs , Fried Rice, Eggplant, Lettuce Salad, Pumpkin Pie 28. Corned Beef Hash... Meatballs , Rice, Beets, Jellied Fruit Salad, Marble Cake 81. Fish Sandwich, Fritters, Okra, Lettuce Salad, Chocolate Chip Cookies 82. Baked Macaroil...Radishes, Lettuce Salad, Bread Pudding 88 Cheesf j ", -tashea Potatoes, Cauliflower, M-.*©!.! Pm’r Sol ad, Apricot Pie 89. Meatbal ! Submarine Sandwich

PIES applications to NCSX

NASA Astrophysics Data System (ADS)

Monticello, D. A.; Pomphrey, N.; Reiman, A. H.

1999-11-01

The PIES ( Reiman, A. H., Greenside, H. S., Compt. Phys. Commun. 43), (1986) code will be used to evaluate the flux surface quality of NCSX. In addition, we have generalized the Cary-Hanson technique for minimizing vacuum islands to the case where finite pressure and current exist in the plasma. We will use this technique to develop trim coils and other methods for repairing broken flux surfaces if they are found in NCSX.

Challenging Notions of Academic Entitlement and Its Rise among Liberal Arts College Students.

PubMed

Lemke, Debra; Marx, Jeff; Dundes, Lauren

2017-12-06

To assess academic entitlement, we employed a repeated cross-sectional design to compare survey data from two systematic random samples collected eight years apart, in 2009 ( n = 225) and 2017 ( n = 159), at a small, private, mid-Atlantic liberal arts college. According to an entitlement scale (based on Greenberger et al., 2008), students were less likely to be entitled in 2017 (27%) than in 2009 (41%) ( p = 0.02). In 2009, a higher proportion of males than females felt entitled (50% versus 34%, p = 0.05), a sex difference that disappeared by 2017. To explore academic entitlement further, we developed the "PIE" scale to measure the extent to which students believe "participation," "improvement" and "effort" should help determine their course grades. Although the proportion of above average PIE scorers was stable from 2009 (36%) to 2017 (34%), in 2017, more females than males were above average on PIE (26% of males versus 44% of females, p = 0.02). PIE, or the desire for recognition of "academic sweat equity," could reflect students' support for a learning model that goes beyond mastery and is more developmental and process oriented. These data challenge common conceptions of what constitutes academic entitlement, the belief that it is rising, and suggest continued discussions of what factors should determine grades.

Vortex wake, downwash distribution, aerodynamic performance and wingbeat kinematics in slow-flying pied flycatchers.

PubMed

Muijres, Florian T; Bowlin, Melissa S; Johansson, L Christoffer; Hedenström, Anders

2012-02-07

Many small passerines regularly fly slowly when catching prey, flying in cluttered environments or landing on a perch or nest. While flying slowly, passerines generate most of the flight forces during the downstroke, and have a 'feathered upstroke' during which they make their wing inactive by retracting it close to the body and by spreading the primary wing feathers. How this flight mode relates aerodynamically to the cruising flight and so-called 'normal hovering' as used in hummingbirds is not yet known. Here, we present time-resolved fluid dynamics data in combination with wingbeat kinematics data for three pied flycatchers flying across a range of speeds from near hovering to their calculated minimum power speed. Flycatchers are adapted to low speed flight, which they habitually use when catching insects on the wing. From the wake dynamics data, we constructed average wingbeat wakes and determined the time-resolved flight forces, the time-resolved downwash distributions and the resulting lift-to-drag ratios, span efficiencies and flap efficiencies. During the downstroke, slow-flying flycatchers generate a single-vortex loop wake, which is much more similar to that generated by birds at cruising flight speeds than it is to the double loop vortex wake in hovering hummingbirds. This wake structure results in a relatively high downwash behind the body, which can be explained by the relatively active tail in flycatchers. As a result of this, slow-flying flycatchers have a span efficiency which is similar to that of the birds in cruising flight and which can be assumed to be higher than in hovering hummingbirds. During the upstroke, the wings of slowly flying flycatchers generated no significant forces, but the body-tail configuration added 23 per cent to weight support. This is strikingly similar to the 25 per cent weight support generated by the wing upstroke in hovering hummingbirds. Thus, for slow-flying passerines, the upstroke cannot be regarded as inactive, and the tail may be of importance for flight efficiency and possibly manoeuvrability.

An East to West Mineralogical Trend in Mars Exploration Rover Spirit Moessbauer Spectra of Home Plate

NASA Technical Reports Server (NTRS)

Schroder, C.; Di, K.; Morris, R. V.; Klingelhofer, G.; Li, R.

2008-01-01

Home Plate is a light-toned plateau approx.90 m in diameter within the Inner Basin of the Columbia Hills in Gusev crater on Mars. It is the most extensive exposure of layered bedrock encountered by Spirit to date, and it is composed of clastic rocks of moderately altered alkali basalt composition, enriched in some highly volatile elements. Textural observations suggest an explosive origin and geochemical observations favor volcanism, probably a hydrovolcanic explosion [1]. Since it first arrived at Home Plate on sol 744, Spirit has circumnavigated the plateau (Fig. 1) and is now, since sol 1410, resting at its Winter Haven 3 location at the north end of Home Plate. Results: The MER Moessbauer spectrometers determine Fe oxidation states, identify Fe-bearing mineral phases and quantify the distribution of Fe among oxidation states and mineral phases [2]. Moessbauer spectra of Home Plate bedrock were obtained in five different locations from nine different targets (Fig. 1): Barnhill Ace, Posey Manager, and James Cool Papa Bell Stars at the northwest side of Home Plate; Pesapallo, June Emerson, and Elizabeth Emery on the east side; Texas Chili on the south side; Pecan Pie on the west side; and Chanute on the north side.

Food and Drug Administration: Insufficient Planning for Field Laboratory Consolidation Decisions.

DTIC Science & Technology

1987-12-04

adequately 5 address whether FDA could meet its current and future laboratory needs if the five laboratories were closed or whether cost- effective ...pie transit and laboratory processing times would lessen FDA’S regula- tory effectiveness . Moreover, 61 percent of the excess laboratory capacity...FDA believes that it can ship sam- pies from across the nation to almost any location for analysis without reducing its regulatory effectiveness . (See

Coupling of PIES 3-D Equilibrium Code and NIFS Bootstrap Code with Applications to the Computation of Stellarator Equilibria

NASA Astrophysics Data System (ADS)

Monticello, D. A.; Reiman, A. H.; Watanabe, K. Y.; Nakajima, N.; Okamoto, M.

1997-11-01

The existence of bootstrap currents in both tokamaks and stellarators was confirmed, experimentally, more than ten years ago. Such currents can have significant effects on the equilibrium and stability of these MHD devices. In addition, stellarators, with the notable exception of W7-X, are predicted to have such large bootstrap currents that reliable equilibrium calculations require the self-consistent evaluation of bootstrap currents. Modeling of discharges which contain islands requires an algorithm that does not assume good surfaces. Only one of the two 3-D equilibrium codes that exist, PIES( Reiman, A. H., Greenside, H. S., Compt. Phys. Commun. 43), (1986)., can easily be modified to handle bootstrap current. Here we report on the coupling of the PIES 3-D equilibrium code and NIFS bootstrap code(Watanabe, K., et al., Nuclear Fusion 35) (1995), 335.

Hague climate talks collapse, new round called for next year

NASA Astrophysics Data System (ADS)

Showstack, Randy

When it comes to global greenhouse gas emissions, the U.S. slice of the pie amounts to roughly one-fourth.For one moment on November 22, though, the U.S. chief negotiator to the Sixth Conference of the Parties (COP 6) of the United Nations Framework Convention on Climate Change wore the entire (custard) pie on his face and suit coat, courtesy of a protester pushing for stronger U.S. support to cut industrial emissions.

PIE preparation of the MEGAPIE target

NASA Astrophysics Data System (ADS)

Wohlmuther, Michael; Wagner, Werner

2012-12-01

The MEGAPIE target, after successfully operating for 4 months at a beam power of 0.77 MW, is now being prepared for post irradiation examination PIE. The lead-bismuth eutectic (LBE) target was irradiated from August until December 2006, and in this period received a beam charge of 2.8 A h of 575 MeV protons. After that, the target was stored in the target storage facility of PSI, waiting for its post irradiation examination. In the meantime several campaigns of tests have been conducted by PSI and ZWILAG, the interim storage facility of Swiss nuclear power plants. In these tests the feasibility of the conditioning of the target and the extraction of sample material for the PIE has been proven. After transport to the hot cell facility at ZWILAG in June 2009, the dismantling of the MEGAPIE target started. It finally was cut into 21 pieces. Ten of these pieces will be shipped to the Hot Laboratory of PSI ('PSI hotlab') to extract samples from the structural materials as well as from the LBE. Currently it is foreseen that the sample extraction will start in the first half of 2011. The remaining parts of the MEGAPIE target were conditioned as radioactive waste. The present paper will mainly focus on the dismantling and first visual inspection of the MEGAPIE target. In addition an outlook on the PIE phase of MEGAPIE is given.

Capital requirements for the transportation of energy materials based on PIES Scenario estimates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gezen, A.; Kendrick, M.J.; Khan, S.S.

In May 1978, Transportation and Economic Research Associates (TERA), Inc. completed a study in which information and methodologies were developed for the determination of capital requirements in the transportation of energy materials. This work was designed to aid EIA in the analysis of PIES solutions. The work consisted of the development of five algorithms which are used to estimate transportation-investment requirements associated with energy commodities and transportation modes. For the purpose of this analysis, TERA was provided with three PIES-solution scenarios for 1985. These are: Scenario A which assumes a high domestic economic rate of growth along with its correspondingmore » high demand for petroleum, as well as a high domestic supply of petroleum; Scenario C which assumes a medium level of economic growth and petroleum demand and supply; and Scenario E which assumes a low level of economic growth and domestic demand and supply for petroleum. Two PIES-related outputs used in TERA's analysis are the ''COOKIE'' reports which present activity summaries by region and ''PERUSE'' printouts of solution files which give interregional flows by energy material. Only the transportation of four energy materials, crude oil, petroleum products, natural gas, and coal is considered. In estimating the capital costs of new or expanded capacity for the transportation of these materials, three transportation modes were examined: pipelines, water carriers (inland barge and deep draft vessels), and railroads. (MCW)« less

Relating the effects of protein type and content in increased-protein cheese pies to consumers' perception of satiating capacity.

PubMed

Marcano, J; Varela, P; Fiszman, S

2015-02-01

Since proteins have been shown to have the highest satiation-inducing effects of all the macronutrients, increasing the protein level is one of the main strategies for designing foods with enhanced satiating capacity. However, few studies analyze the effect that protein addition has on the texture and flavor characteristics of the target food item to relate it to the expected satiating capacity it elicits. The present work studied cheese pies with three levels of soy and whey proteins. Since the protein level altered the rheological behavior of the batters before baking and the texture of the baked pies, the feasibility of adding several protein levels for obtaining a range of final products was investigated. A check-all-that-apply questionnaire containing 32 sensory and non-sensory characteristics of the samples was given to consumers (n = 131) who also scored the perceived samples' satiating capacity. The results showed that the type and content of protein contributed distinctive sensory characteristics to the samples that could be related to their satiating capacity perception. Harder and drier samples (high protein levels) were perceived as more satiating with less perceptible sweet and milky cheese pie characteristic flavors. Soy contributed an off-flavour. These results will contribute to a better understanding of the interrelation of all these factors, aiding the development of highly palatable solid foods with enhanced satiating capacities.

Undercar Electrical Generator for Railway Passenger Cars: Improvement of Efficiency / Dzelzceļa Pasažieru Zemvagona Elektriskā Ģeneratora Efektivitātes Uzlabošana

NASA Astrophysics Data System (ADS)

Levin, N.; Kamolins, E.; Gusakov, A.; Pugachev, V.

2013-04-01

Passenger cars of the railway transport are being constantly improved, thus becoming ever more comfortable for public conveyance. These cars are fitted with air conditioners, installations for heating and forced ventilation, heaters, refrigerators; lighting, radio and TV sets; communication equipment, etc. All the listed fittings need continuous and secure electricity supply from a primary independent source. The paper considers the possibilities of meeting requirements for particular power supply systems - first of all for undercar generators. At operation of such a high-power generator under rugged conditions it should be highly reliable, possessing a reasonable mass and high efficiency. The existing designs of these generators still do not meet the listed requirements in full measure. To improve the efficiency of the undercar generator it is proposed to integrate its excitation winding into the armature one, thus reducing the copper consumption, losses and mass, while - which is the most important - considerably raising reliability of the generator and its availability factor. Dzelzceļa transporta pasažieru vilcienu vagoni nepārtraukti tiek pilnveidoti ar mērķi paaugstināt pasažieru komforta līmeni pārvadājumu laikā. Šādi pasažieru vagoni aprīkoti ar gaisa kondicionēšanas, apsildes, ventilācijas, ūdens uzsildīšanas, saldēšanas, apgaismes, radio, televīzijas, sakaru u.c. iekārtām. Visām pieminētajām iekārtām to darbības laikā ir nepieciešama nepārtraukta un droša elektroenerģijas apgāde no primāra neatkarīga avota. Darbā tiek izskatīta elektroapgādes sistēma, kura spētu nodrošināt izvirzītās prasības. Pie šīs sistēmas, pirmkārt, pieder zemvagona ģenerators. Tam ir jābūt paaugstinātas jaudas, smagos darba apstākļos jānodrošina augsts drošums, ar pieņemamu masu un augstu lietderības koeficientu. Šādu ģeneratoru esošās konstrukcijas pilnā mērā nespēj nodrošināt iepriekš minētās prasības. Lai paaugstinātu zemvagona ģeneratora efektivitāti, tiek piedāvāts elektriski integrēt tā ierosmes tinumu enkura tinumā, turklāt samazinot izmantojamā vara apjomu, zudumus, masu, bet, galvenais, būtiski paaugstinot drošumu un gatavības koeficientu.

5 new ways to look at generating revenue.

PubMed

Sturm, Arthur C

2009-11-01

A healthcare organization's "strategic pie" has four pieces: physician retention, brand, patient retention, and patient acquisition. When allocating strategic effort among these pieces of the pie, leading hospitals are following the lead of other industries, focusing on concepts such as churn rate, downstream value, strategic halo, promotable products, and the relative power of different metrics. A risk-reward metric offers an important means of assessing factors that would influence how much you would be willing to spend for specific purposes, such as acquiring new patients.

Efficient Computation of Difference Vibrational Spectra in Isothermal-Isobaric Ensemble.

PubMed

Joutsuka, Tatsuya; Morita, Akihiro

2016-11-03

Difference spectroscopy between two close systems is widely used to augment its selectivity to the different parts of the observed system, though the molecular dynamics calculation of tiny difference spectra would be computationally extraordinary demanding by subtraction of two spectra. Therefore, we have proposed an efficient computational algorithm of difference spectra without resorting to the subtraction. The present paper reports our extension of the theoretical method in the isothermal-isobaric (NPT) ensemble. The present theory expands our applications of analysis including pressure dependence of the spectra. We verified that the present theory yields accurate difference spectra in the NPT condition as well, with remarkable computational efficiency over the straightforward subtraction by several orders of magnitude. This method is further applied to vibrational spectra of liquid water with varying pressure and succeeded in reproducing tiny difference spectra by pressure change. The anomalous pressure dependence is elucidated in relation to other properties of liquid water.

Portable inference engine: An extended CLIPS for real-time production systems

NASA Technical Reports Server (NTRS)

Le, Thach; Homeier, Peter

1988-01-01

The present C-Language Integrated Production System (CLIPS) architecture has not been optimized to deal with the constraints of real-time production systems. Matching in CLIPS is based on the Rete Net algorithm, whose assumption of working memory stability might fail to be satisfied in a system subject to real-time dataflow. Further, the CLIPS forward-chaining control mechanism with a predefined conflict resultion strategy may not effectively focus the system's attention on situation-dependent current priorties, or appropriately address different kinds of knowledge which might appear in a given application. Portable Inference Engine (PIE) is a production system architecture based on CLIPS which attempts to create a more general tool while addressing the problems of real-time expert systems. Features of the PIE design include a modular knowledge base, a modified Rete Net algorithm, a bi-directional control strategy, and multiple user-defined conflict resolution strategies. Problems associated with real-time applications are analyzed and an explanation is given for how the PIE architecture addresses these problems.

Outbreak of Salmonella enterica serotype I 4,5,12:i:- infections: the challenges of hypothesis generation and microwave cooking.

PubMed

Mody, R K; Meyer, S; Trees, E; White, P L; Nguyen, T; Sowadsky, R; Henao, O L; Lafon, P C; Austin, J; Azzam, I; Griffin, P M; Tauxe, R V; Smith, K; Williams, I T

2014-05-01

We investigated an outbreak of 396 Salmonella enterica serotype I 4,5,12:i:- infections to determine the source. After 7 weeks of extensive hypothesis-generation interviews, no refined hypothesis was formed. Nevertheless, a case-control study was initiated. Subsequently, an iterative hypothesis-generation approach used by a single interviewing team identified brand A not-ready-to-eat frozen pot pies as a likely vehicle. The case-control study, modified to assess this new hypothesis, along with product testing indicated that the turkey variety of pot pies was responsible. Review of product labels identified inconsistent language regarding preparation, and the cooking instructions included undefined microwave wattage categories. Surveys found that most patients did not follow the product's cooking instructions and did not know their oven's wattage. The manufacturer voluntarily recalled pot pies and improved the product's cooking instructions. This investigation highlights the value of careful hypothesis-generation and the risks posed by frozen not-ready-to-eat microwavable foods.

Precision Information Environment (PIE) for International Safeguards: Pre-Demonstration Development Use Cases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gastelum, Zoe N.; Henry, Michael J.

2013-11-13

In FY2013, the PIE International Safeguards team demonstrated our development progress to U.S. Department of Energy (DOE) staff from the Office of Nonproliferation and International Security (NA-24, our client) and the Office of Defense Nuclear Nonproliferation Research and Development (NA-22). Following the demonstration, the team was asked by our client to complete additional development prior to a planned demonstration at the International Atomic Energy Agency (IAEA), scheduled tentatively for January or spring of 2014. The team discussed four potential areas for development (in priority order), and will develop them as time and funding permit prior to an IAEA demonstration. Themore » four capability areas are: 1. Addition of equipment manuals to PIE-accessible files 2. Optical character recognition (OCR) of photographed text 3. Barcode reader with information look-up from a database 4. Add Facilities to Data Model 5. Geospatial capabilities with information integration Each area will be described below in a use case.« less

The Perceived Invalidation of Emotion Scale (PIES): Development and psychometric properties of a novel measure of current emotion invalidation.

PubMed

Zielinski, Melissa J; Veilleux, Jennifer C

2018-05-24

Emotion invalidation is theoretically and empirically associated with mental and physical health problems. However, existing measures of invalidation focus on past (e.g., childhood) invalidation and/or do not specifically emphasize invalidation of emotion. In this article, the authors articulate a clarified operational definition of emotion invalidation and use that definition as the foundation for development of a new measure of current perceived emotion invalidation across a series of five studies. Study 1 was a qualitative investigation of people's experiences with emotional invalidation from which we generated items. An initial item pool was vetted by expert reviewers in Study 2 and examined via exploratory factor analysis in Study 3 within both college student and online samples. The scale was reduced to 10 items via confirmatory factor analysis in Study 4, resulting in a brief but psychometrically promising measure, the Perceived Invalidation of Emotion Scale (PIES). A short-term longitudinal investigation (Study 5) revealed that PIES scores had strong test-retest reliability, and that greater perceived emotion invalidation was associated with greater emotion dysregulation, borderline features and symptoms of emotional distress. In addition, the PIES predicted changes in relational health and psychological health over a 1-month period. The current set of studies thus presents a psychometrically promising and practical measure of perceived emotion invalidation that can provide a foundation for future research in this burgeoning area. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

African departure rather than migration speed determines variation in spring arrival in pied flycatchers.

PubMed

Ouwehand, Janne; Both, Christiaan

2017-01-01

Properly timed spring migration enhances reproduction and survival. Climate change requires organisms to respond to changes such as advanced spring phenology. Pied flycatchers Ficedula hypoleuca have become a model species to study such phenological adaptations of long-distance migratory songbirds to climate change, but data on individuals' time schedules outside the breeding season are still lacking. Using light-level geolocators, we studied variation in migration schedules across the year in a pied flycatcher population in the Netherlands, which sheds light on the ability for individual adjustments in spring arrival timing to track environmental changes at their breeding grounds. We show that variation in arrival dates to breeding sites in 2014 was caused by variation in departure date from sub-Saharan Africa and not by environmental conditions encountered en route. Spring migration duration was short for all individuals, on average 2 weeks. Males migrated ahead of females in spring, while migration schedules in autumn were flexibly adjusted according to breeding duties. Individuals were therefore not consistently early or late throughout the year. In fast migrants like our Dutch pied flycatchers, advancement of arrival to climate change likely requires changes in spring departure dates. Adaptation for earlier arrival may be slowed down by harsh circumstances in winter, or years with high costs associated with early migration. © 2016 The Authors. Journal of Animal Ecology published by John Wiley & Sons Ltd on behalf of British Ecological Society.

Threshold ionization spectroscopic investigation of supersonic jet-cooled, laser-desorbed Tryptophan

NASA Astrophysics Data System (ADS)

Taherkhani, Mehran; Armentano, Antonio; Černý, Jiří; Müller-Dethlefs, Klaus

2016-07-01

Tryptophan (Trp) was studied by two-colour Photoionization Efficiency (PIE) and Mass Analysed Threshold Ionization (MATI) spectroscopy using a laser desorption apparatus. Conformer A of Trp was excited into the S1 state (34,878 cm-1) and the second laser was scanned around the D0 cation ground and the D1 excited state. No ionization signal into the D0 state could be found, but a clear threshold was observed for the D1 state with an ionization energy of 66,704 ± 3 cm-1 (8.27 eV). This observation is explained in terms of the electronic configurations of the S1 and cationic states.

Calling Where It Counts: Subordinate Pied Babblers Target the Audience of Their Vocal Advertisements.

PubMed

Humphries, David J; Finch, Fiona M; Bell, Matthew B V; Ridley, Amanda R

2015-01-01

For territorial group-living species, opportunities to reproduce on the natal territory can be limited by a number of factors including the availability of resources within a territory, access to unrelated individuals, and monopolies on reproduction by dominant group members. Individuals looking to reproduce are therefore faced with the options of either waiting for a breeding opportunity to arise in the natal territory, or searching for reproductive opportunities in non-natal groups. In the cooperatively breeding Southern pied babbler, Turdoides bicolor, most individuals who achieve reproductive success do so through taking up dominant breeding positions within non-natal groups. For subordinate pied babblers therefore, searching for breeding opportunities in non-natal groups is of primary importance as this represents the major route to reproductive success. However, prospecting (where individuals leave the group to search for reproductive opportunities within other groups) is costly and individuals rapidly lose weight when not part of a group. Here we demonstrate that subordinate pied babblers adopt an alternative strategy for mate attraction by vocal advertisement from within their natal territories. We show that subordinates focus their calling efforts on the edges of their territory, and specifically near boundaries with neighbouring groups that have potential breeding partners (unrelated individuals of the opposite sex). In contrast to prospecting, calling individuals showed no body mass loss associated with this behaviour, suggesting that calling from within the group may provide a 'cheap' advertisement strategy. Additionally, we show that subordinates use information regarding the composition of neighbouring groups to target the greatest number of potential mating partners.

Psychrophilic and Mesophilic Fungi in Frozen Food Products

PubMed Central

Kuehn, Harold H.; Gunderson, Millard F.

1963-01-01

The mold flora of certain frozen pastries and chicken pies was investigated. Molds were determined qualitatively or quantitatively, or both, by preparing pour plates of the blended product and incubating the plates at various temperatures. The mesophilic fungal flora developed on plates incubated at 10 and 20 C, whereas psychrophilic fungi were obtained on plates incubated at 0 and 5 C. About 2,000 cultures of fungi, representing about 100 different species, were isolated from various products. Four different brands of blueberry, two brands of cherry pastries, two brands of apple, and one brand of raspberry pastries were examined. In addition, two brands of chicken pies were studied. Blueberry pastries had a much higher total fungal population than the other products, although different brands of blueberry pastries varied considerably. Blueberry pastries had from 347 to 1,586 psychrophilic fungi per g. Cherry pastries had about 70 to 110 psychrophiles per g, and apple pastries had 19 to 92 psychrophiles per g. Chicken pies contained very few psychrophilic fungi, about 15 per g. Aureobasidium pullulans was recovered most frequently. About 90% of the psychrophilic fungi found in blueberry products was A. pullulans. Depending upon the brand of cherry pastry, either Phoma spp. or A. pullulans was the most common fungus present. Apple pastries also displayed brand variation, but were unique in having many mesophilic aspergilli. This genus was generally absent from other products. The Penicillium content of apple pastries was also rather high; 50% of the psychrophilic flora was represented by this genus. The psychrophilic fungal flora of chicken pies was composed primarily of penicillia (50%) and Chrysosporium pannorum (46%). PMID:13927344

A soma-to-germline transformation in long-lived C. elegans mutants

PubMed Central

Curran, Sean P.; Wu, Xiaoyun; Riedel, Christian G.; Ruvkun, Gary

2009-01-01

Unlike the soma which ages during the lifespan of multicellular organisms, the germline traces an essentially immortal lineage. Genomic instability in somatic cells increases with age, and this decline in somatic maintenance might be regulated to facilitate resource reallocation toward reproduction at the expense of cellular senescence. We report here that C. elegans mutants with increased longevity exhibit a soma-to-germline transformation of gene expression programs normally limited to the germline. Decreased insulin-like signaling causes the somatic misexpression of germline-limited pie-1 and pgl family of genes in intestinal and ectodermal tissues. DAF-16/FoxO, the major transcriptional effector of insulin-like signaling, regulates pie-1 expression by directly binding to the pie-1 promoter. The somatic tissues of insulin-like mutants are more germline-like and protected from genotoxic stress. Gene inactivation of components of the cytosolic chaperonin complex that induce increased longevity also cause somatic misexpression of PGL-1. These results suggest that the acquisition of germline characteristics by the somatic cells of C. elegans mutants with increased longevity contributes to their increased health and survival. PMID:19506556

Guide to using Cuechart, Tellagraf, and Disspla at ANL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertoncini, P.J.; Thommes, M.M.

1986-01-01

Guide to Curchart, Tellagraf, and Disspla at ANL provides information necessary for using the three ISSCO graphics packages at Argonne: Cuechart is a cue-and-response program available in CMS that aids users in creating bar charts, line charts, pie charts, and word charts. It is appropriate for users with little or no previous graphics experience. Cuechart provides much of the capability of Tellagraf without the user's having to learn Tellagraf commands. Tellagraf is a more powerful, easy-to-use graphics package also available in CMS. With a little training, scientists, administrators, and secretaries can produce sophisticated publication-quality log or linear plots, bar charts,more » pie charts, tables, or posters. Disspla is a more versatile and sophisticated graphics package. It is available in both CMS and batch and consists of several hundred Fortran-callable and PL/I-callable subroutines that will enable you to obtain professional quality plots. In addition to log or linear plots, bar charts, pie charts, and pages of text, Disspla provides subroutines for contour plots, 3-D plots, and world maps.« less

Magnetic Resonance Imaging: A Tool for Pork Pie Development

PubMed Central

Gaunt, Adam P.; Morris, Robert H.; Newton, Michael I.

2013-01-01

The traditional British pork pie consists of roughly chopped pork cooked in a hot water pastry crust. Due to shrinkage of the meat during cooking, the gap formed around the meat is usually sealed using a gelatin based jelly to exclude air and thus help to preserve the pie. The properties of the jelly are such that it will ingress into the pastry crust causing undesirable softening. The jelly is traditionally produced by simmering pig trotters with seasoning for several hours. In this work we demonstrate the potential of magnetic resonance imaging (MRI) as a tool for investigating the conditions required for producing jellies with different properties and present two examples of this use. Firstly we demonstrate that MRI can determine the ability of water to diffuse through the jelly which is critical in minimizing the amount of moisture moving from the jelly to the crust. Secondly, the impact of jelly temperature on the penetration length into the crust is investigated. These examples highlight the power of MRI as a tool for food assessment. PMID:28239124

A Comparison Between Two Types of Preventive Educational Programs for a Population at High Risk for Cardiovascular Disease

DTIC Science & Technology

1988-08-01

140 lard 900 pies 250-350 pecans 696 milk choc. nuts 542 raw peanuts 543 chocolate fudge 390 pea nut butter 576 no-fat yogurt sweetened 40 cashew ...list first ingredient on label (L) U U U U Salad dressing (L) UU U U Kind Peanut butter (L) U i U U U Nuts and seeds (L) U U U U U Fried meats or...cheese, butter, margarine, nuts , peanut butter and foods which contain refined sugars such as ice cresm., puddings, pies, cakes, candies etc. Foods

Optical ptychographic microscopy for quantitative anisotropic phase imaging

NASA Astrophysics Data System (ADS)

Anthony, N.; Cadenazzi, G.; Nugent, K. A.; Abbey, B.

2016-12-01

Ptychography has recently been adapted for the recovery of the complete Jones matrix of an anisotropic specimen, using a vectorial form of the Ptychographic Iterative Engine (vPIE) for a set of linearly polarized probes. Here we show that this method can be applied to the recovery of the in-plane components of the elastic strain tensor in a diametrically compressed disc. The advantages and disadvantages of vPIE for the recovery of strain information from `real-world' samples is discussed as well as the potential for this approach to be applied to the characterization of the mechanical properties of optically transparent materials

Evaluation of the Spectra Optia apheresis system for mononuclear cell (MNC) collection in G-CSF mobilized and nonmobilized healthy donors: results of a multicenter study.

PubMed

Karafin, Matthew S; Graminske, Sharon; Erickson, Paulette; Walters, Mark C; Scott, Edward P; Carter, Scott; Padmanabhan, Anand

2014-10-01

The Spectra Optia apheresis system is a newer centrifugation-based device that in comparison with the COBE Spectra includes features that enhance procedure automation and usability. In this FDA-approved three-center two-arm observational study we characterized the performance of the Spectra Optia for collection of MNCs and CD34+ cells from nonmobilized and granulocyte-colony stimulating factor (G-CSF) mobilized healthy donors, respectively. There were a total of 15 evaluable subjects in each arm. Key performance indicators included collection efficiency of MNCs/CD34+ cells, product purity and cellular viability. For nonmobilized donors, median MNC collection efficiency, platelet collection efficiency, product hematocrit and granulocyte contamination were 57%, 12%, 4%, and 1.7%, respectively. For mobilized donors, median MNC collection efficiency, CD34+ cell collection efficiency, platelet collection efficiency, product hematocrit and granulocyte contamination were 61%, 77%, 19%, 4%, and 15%, respectively. Average WBC viability in the mobilized products was 99%. There was one severe (grade 3) adverse event related to citrate toxicity. This study demonstrates that the Spectra Optia can be used for safe and efficacious collection of MNCs, and results obtained are in line with expectations on collection efficiency and product characteristics. Adverse events were limited to those that are well documented in the stem-cell mobilization and leukapheresis process. As of the time of this writing, FDA 510(k) approval for use of the Spectra Optia device for MNC collection was achieved in the US based partly on the results of this study. © 2014 Wiley Periodicals, Inc.

Vitamin profiles in two free-living passerine birds under a metal pollution gradient - A calcium supplementation experiment.

PubMed

Ruiz, Sandra R; Espín, Silvia; Sánchez-Virosta, Pablo; Salminen, Juha-Pekka; Lilley, Thomas M; Eeva, Tapio

2017-04-01

Vitamin and carotenoid deficiency may impair development in free-living vertebrates, because of the importance of these micronutrients to growth, antioxidant defense and calcium regulation. Micronutrient and calcium insufficiency can be intensified by metal pollution which can interfere with nutrient homeostasis or indirectly reduce food availability. Furthermore, absorption of dietary heavy metals is dependent on food calcium and vitamin levels. We investigated the effect of calcium on plasma vitamin and carotenoid profiles and how these affected growth and survival in two passerine birds with different calcium turnover living along a metal pollution gradient. Vitamins (A, D 3 and E) and carotenoids were quantified from blood plasma of great tit (Parus major) and pied flycatcher (Ficedula hypoleuca) nestlings. Metal concentrations in soil and in feces from the same nestlings were used to assess the exposure to air pollution. Additionally, we examined the vitamin level variation between developmental stages (eggs and nestlings within the same brood). Our results showed that generally higher concentrations of vitamins and carotenoids circulate in blood of great tits than in pied flycatchers. In general, birds inhabiting the polluted zone presented lower concentrations of the studied micronutrients. Calcium supplementation and metal pollution decreased vitamin A concentration in pied flycatcher, but not in great tit, while vitamin A affected growth and survival in great tit and pied flycatcher respectively. Our results suggest that populations under exposure to metal pollution may experience increased vitamin A deficiency, and that the two passerine species, while obtaining similar micronutrients in food, respond differently to environmental disturbance of nutrients. Copyright © 2017 Elsevier Inc. All rights reserved.

Bifidobacterium breve MCC-117 Induces Tolerance in Porcine Intestinal Epithelial Cells: Study of the Mechanisms Involved in the Immunoregulatory Effect

PubMed Central

MURATA, Kozue; TOMOSADA, Yohsuke; VILLENA, Julio; CHIBA, Eriko; SHIMAZU, Tomoyuki; ASO, Hisashi; IWABUCHI, Noriyuki; XIAO, Jin-zhong; SAITO, Tadao; KITAZAWA, Haruki

2014-01-01

Bifidobacterium breve MCC-117 is able to significantly reduce the expression of inflammatory cytokines in porcine intestinal epithelial (PIE) cells and to improve IL-10 levels in CD4+CD25high Foxp3+ lymphocytes in response to heat-stable enterotoxigenic Escherichia coli (ETEC) pathogen-associated molecular patterns (PAMPs), while the immunoregulatory effect of B. adolescentis ATCC15705 was significantly lower than that observed for the MCC-117 strain. Considering the different capacities of the two bifidobacterium strains to activate toll-like receptor (TLR)-2 and their differential immunoregulatory activities in PIE and immune cells, we hypothesized that comparative studies with both strains could provide important information regarding the molecular mechanism(s) involved in the anti-inflammatory activity of bifidobacteria. In this work, we demonstrated that the anti-inflammatory effect of B. breve MCC-117 was achieved by a complex interaction of multiple negative regulators of TLRs as well as inhibition of multiple signaling pathways. We showed that B. breve MCC-117 reduced heat-stable ETEC PAMP-induced NF-κB, p38 MAPK and PI3 K activation and expression of pro-inflammatory cytokines in PIE cells. In addition, we demonstrated that B. breve MCC-117 may activate TLR2 synergistically and cooperatively with one or more other pattern recognition receptors (PRRs), and that interactions may result in a coordinated sum of signals that induce the upregulation of A20, Bcl-3, Tollip and SIGIRR. Upregulation of these negative regulators could have an important physiological impact on maintaining or reestablishing homeostatic TLR signals in PIE cells. Therefore, in the present study, we gained insight into the molecular mechanisms involved in the immunoregulatory effect of B. breve MCC-117. PMID:24936377

Captive breeding and reintroduction of the oriental pied hornbill (Anthracoceros albirostris) in Khao Kheow Open Zoo, Thailand.

PubMed

Chaiyarat, Rattanawat; Kongprom, Urarikha; Manathamkamon, Darika; Wanpradab, Sunan; Sangarang, Satean

2012-01-01

This article discusses two related issues of the captive breeding and reintroduction of the Oriental pied hornbill (Anthracoceros albirostris) in order to increase its population in the natural habitats. Oriental pied hornbills were bred in Khao Kheow Open Zoo. Three pairs were separated and kept in breeding cages. Females occupied artificial nests between February and April 2005-2007. Eggs were laid and incubated between February and March each year from 2005 to 2007. Nestlings hatched in late March and left the nest in late April 2005-2007. Each breeding pair was fed with approximately 400 g of food each day. All three pairs reproduced resulting in mature offspring of seven in 2005, six in 2006, and five in 2007. Four of sixteen 3-year-old birds were randomly selected and equipped with a GPS receiver on their backs. Activities of the birds attached and unattached with GPS were not significantly different. The first two birds (one female, one male with GPS) were reintroduced on August 5, 2006, and another nine birds (four birds with GPS) were reintroduced on December 26, 2006. The average home range of these reintroduced birds was 0.13 km(2) . Their foods consisted of wild plants and animals in the home range. The first reintroduced pair was able to breed naturally by laying and hatching eggs in an artificial nest. Two juveniles left the nest in April 2008. These results indicate that both captive breeding and reintroduction are potentially important ways to increase the population of the Oriental pied hornbill in natural habitats. © 2011 Wiley Periodicals, Inc.

Fluid Physics

NASA Image and Video Library

2001-05-31

Whipped cream and the filling for pumpkin pie are two familiar materials that exhibit the shear-thinning effect seen in a range of industrial applications. It is thick enough to stand on its own atop a piece of pie, yet flows readily when pushed through a tube. This demonstrates the shear-thinning effect that was studied with the Critical Viscosity of Xenon Experiment (CVX-2) on the STS-107 Research 1 mission in 2002. CVX observed the behavior of xenon, a heavy inert gas used in flash lamps and ion rocket engines, at its critical point. The principal investigator was Dr. Robert Berg of the National Institutes of Standards and Technology in Gaithersburg, MD.

KSC-08pd4121

NASA Image and Video Library

2008-12-22

CAPE CANAVERAL, Fla. – Near NASA's Kennedy Space Center in Florida, a pied-billed Grebe swims on a pond in the Merritt island National Wildlife Refuge. The normal black band on its bill is lacking in winter. The most common grebe in eastern North America, the pied-billed Grebe inhabits marshes and ponds, eating small fish, crustaceans, especially crayfish, and aquatic insects. The center shares a boundary with the refuge that includes salt-water estuaries, brackish marshes, hardwood hammocks and pine flatwoods. The diverse landscape provides habitat for more than 310 species of birds, 25 mammals, 117 fishes and 65 amphibians and reptiles. Photo credit: NASA/Jim Grossmann

Free-boundary PIES Calculations

NASA Astrophysics Data System (ADS)

Monticello, D. A.; Reiman, A. H.; Arndt, S. C.; Merkel, P. K.

1998-11-01

A new formulation of the free boundary problem for general three-dimensional configurations has been formulated for the PIES( Reiman, A. H., Greenside, H. S., Compt. Phys. Commun. 43), (1986). code. The new formulation is more flexible and is faster that the original formulation described in Merkel et al(Merkel, P., Johnson, J. L., Monticello, D.A., et al., Proceedings of the Fourteenth International Conference on Plasma Physics and Controlled Nuclear Fusion Research paper IAEA-CN-60 | D-P-II-10) (1994) . These advantages will be described and first results of the application of this new algorithm to W7-X and NCSX (National Compact Stellarator Experiment) configurations will be presented.

Lessons Learned from the Development of an Example Precision Information Environment for International Safeguards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gastelum, Zoe N.; Henry, Michael J.; Burtner, IV, E. R.

The International Atomic Energy Agency (IAEA) is interested in increasing capabilities of IAEA safeguards inspectors to access information that would improve their situational awareness on the job. A mobile information platform could potentially provide access to information, analytics, and technical and logistical support to inspectors in the field, as well as providing regular updates to analysts at IAEA Headquarters in Vienna or at satellite offices. To demonstrate the potential capability of such a system, Pacific Northwest National Laboratory (PNNL) implemented a number of example capabilities within a PNNL-developed precision information environment (PIE), and using a tablet as a mobile informationmore » platform. PNNL’s safeguards proof-of-concept PIE intends to; demonstrate novel applications of mobile information platforms to international safeguards use cases; demonstrate proof-of-principle capability implementation; and provide “vision” for capabilities that could be implemented. This report documents the lessons learned from this two-year development activity for the Precision Information Environment for International Safeguards (PIE-IS), describing the developed capabilities, technical challenges, and considerations for future development, so that developers working to develop a similar system for the IAEA or other safeguards agencies might benefit from our work.« less

PIE on Safety-Tested Loose Particles from Irradiated Compact 4-4-2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunn, John D.; Gerczak, Tyler J.; Morris, Robert Noel

2016-04-01

Post-irradiation examination (PIE) is being performed in support of tristructural isotropic (TRISO) coated particle fuel development and qualification for High Temperature Gas-cooled Reactors (HTGRs). This work is sponsored by the Department of Energy Office of Nuclear Energy (DOE-NE) through the Advanced Reactor Technologies (ART) Office under the Advanced Gas Reactor Fuel Development and Qualification (AGR) Program. The AGR-1 experiment was the first in a series of TRISO fuel irradiation tests initiated in 2006. The AGR-1 TRISO particles and fuel compacts were fabricated at Oak Ridge National Laboratory (ORNL) in 2006 using laboratory-scale equipment and irradiated for 3 years in themore » Advanced Test Reactor (ATR) at Idaho National Laboratory (INL) to demonstrate and evaluate fuel performance under HTGR irradiation conditions. Post-irradiation examination was performed at INL and ORNL to study how the fuel behaved during irradiation, and to test fuel performance during exposure to elevated temperatures at or above temperatures that could occur during a depressurized conduction cooldown event. This report summarizes safety testing and post-safety testing PIE conducted at ORNL on loose particles extracted from irradiated AGR-1 Compact 4-4-2.« less

Inferring the demographic history of European Ficedula flycatcher populations

PubMed Central

2013-01-01

Background Inference of population and species histories and population stratification using genetic data is important for discriminating between different speciation scenarios and for correct interpretation of genome scans for signs of adaptive evolution and trait association. Here we use data from 24 intronic loci re-sequenced in population samples of two closely related species, the pied flycatcher and the collared flycatcher. Results We applied Isolation-Migration models, assignment analyses and estimated the genetic differentiation and diversity between species and between populations within species. The data indicate a divergence time between the species of <1 million years, significantly shorter than previous estimates using mtDNA, point to a scenario with unidirectional gene-flow from the pied flycatcher into the collared flycatcher and imply that barriers to hybridisation are still permeable in a recently established hybrid zone. Furthermore, we detect significant population stratification, predominantly between the Spanish population and other pied flycatcher populations. Conclusions Our results provide further evidence for a divergence process where different genomic regions may be at different stages of speciation. We also conclude that forthcoming analyses of genotype-phenotype relations in these ecological model species should be designed to take population stratification into account. PMID:23282063

Vacuum-ultraviolet photoionization studies of the microhydration of DNA bases (guanine, cytosine, adenine, and thymine).

PubMed

Belau, Leonid; Wilson, Kevin R; Leone, Stephen R; Ahmed, Musahid

2007-08-09

In this work, we report on a photoionization study of the microhydration of the four DNA bases. Gas-phase clusters of water with DNA bases [guanine (G), cytosine (C), adenine (A), and thymine (T)] are generated via thermal vaporization of the bases and expansion of the resultant vapor in a continuous supersonic jet expansion of water seeded in Ar. The resulting clusters are investigated by single-photon ionization with tunable vacuum-ultraviolet synchrotron radiation and mass analyzed using reflectron mass spectrometry. Photoionization efficiency (PIE) curves are recorded for the DNA bases and the following water (W) clusters: G, GWn (n = 1-3); C, CWn (n = 1-3); A, AWn (n = 1,2); and T, TWn (n = 1-3). Appearance energies (AE) are derived from the onset of these PIE curves (all energies in eV): G (8.1 +/- 0.1), GW (8.0 +/- 0.1), GW2 (8.0 +/- 0.1), and GW3 (8.0); C (8.65 +/- 0.05), CW (8.45 +/- 0.05), CW2 (8.4 +/- 0.1), and CW3 (8.3 +/- 0.1); A (8.30 +/- 0.05), AW (8.20 +/- 0.05), and AW2 (8.1 +/- 0.1); T (8.90 +/- 0.05); and TW (8.75 +/- 0.05), TW2 (8.6 +/- 0.1), and TW3 (8.6 +/- 0.1). The AEs of the DNA bases decrease slightly with the addition of water molecules (up to three) but do not converge to values found for photoinduced electron removal from DNA bases in solution.

Enhancing the sensitivity of fluorescence correlation spectroscopy by using time-correlated single photon counting.

PubMed

Lamb, D C; Müller, B K; Bräuchle, C

2005-10-01

Fluorescence correlation spectroscopy (FCS) and fluorescence cross-correlation spectroscopy (FCCS) are methods that extract information about a sample from the influence of thermodynamic equilibrium fluctuations on the fluorescence intensity. This method allows dynamic information to be obtained from steady state equilibrium measurements and its popularity has dramatically increased in the last 10 years due to the development of high sensitivity detectors and its combination with confocal microscopy. Using time-correlated single-photon counting (TCSPC) detection and pulsed excitation, information over the duration of the excited state can be extracted and incorporated in the analysis. In this short review, we discuss new methodologies that have recently emerged which incorporated fluorescence lifetime information or TCSPC data in the FCS and FCCS analysis. Time-gated FCS discriminates between which photons are to be incorporated in the analysis dependent upon their arrival time after excitation. This allows for accurate FCS measurements in the presence of fluorescent background, determination of sample homogeneity, and the ability to distinguish between static and dynamic heterogeneities. A similar method, time-resolved FCS can be used to resolve the individual correlation functions from multiple fluorophores through the different fluorescence lifetimes. Pulsed interleaved excitation (PIE) encodes the excitation source into the TCSPC data. PIE can be used to perform dual-channel FCCS with a single detector and allows elimination of spectral cross-talk with dual-channel detection. For samples that undergo fluorescence resonance energy transfer (FRET), quantitative FCCS measurements can be performed in spite of the FRET and the static FRET efficiency can be determined.

Construction of transformed, cultured silkworm cells and transgenic silkworm using the site-specific integrase system from phage φC31.

PubMed

Yin, Yajuan; Cao, Guangli; Xue, Renyu; Gong, Chengliang

2014-10-01

The Streptomyces bacteriophage, φC31, uses a site-specific integrase enzyme to perform efficient recombination. The recombination system uses specific sequences to integrate exogenous DNA from the phage into a host. The sequences are known as the attP site in the phage and the attB site in the host. The system can be used as a genetic manipulation tool. In this study it has been applied to the transformation of cultured BmN cells and the construction of transgenic Bombyx mori individuals. A plasmid, pSK-attB/Pie1-EGFP/Zeo-PASV40, containing a cassette designed to express a egfp-zeocin fusion gene, was co-transfected into cultured BmN cells with a helper plasmid, pSK-Pie1/NLS-Int/NSL. Expression of the egfp-zeocin fusion gene was driven by an ie-1 promoter, downstream of a φC31 attB site. The helper plasmid encoded the φC31 integrase enzyme, which was flanked by two nuclear localization signals. Expression of the egfp-zeocin fusion gene could be observed in transformed cells. The two plasmids were also transferred into silkworm eggs to obtain transgenic silkworms. Successful integration of the fusion gene was indicated by the detection of green fluorescence, which was emitted by the silkworms. Nucleotide sequence analysis demonstrated that the attB site had been cut, to allow recombination between the attB and endogenous pseudo attP sites in the cultured silkworm cells and silkworm individuals.

Therapeutic plasma exchange: a paired comparison of Fresenius AS104 vs. COBE Spectra.

PubMed

Burgstaler, E A; Pineda, A A

2001-01-01

For therapeutic plasma exchange (TPE), continuous flow separators are known to be efficient as exemplified by Fresenius AS104 and COBE Spectra. The AS104 uses an interface monitoring system in the centrifuge during TPE, whereas Spectra uses computer algorithms to establish the plasma-cell interface. To determine the plasma collection efficiency (PLCE), anticoagulant (AC) volumes used, and platelets (PLT) lost of the AS104 and the Spectra, we performed a prospective paired comparison of 20 TPE (each machine). The study included 17 patients, 1.3 plasma volume exchanges (without AC), equal inlet rates, and AC ratio of 13:1. Processing times did not include reinfuse mode. Platelet loss was determined by sampling the collection bags. Inlet rates were between 60-110 ml/min. Diagnosis included peripheral neuropathies, TTP and cryoglobulinemia. The AS104 had significantly (P<0.0001) lower average whole blood processed (F:6,601 vs. S:8,584 ml), AC volume (F:532 vs. S:719 ml), and processing time (F:80 vs. S:102 minutes) than Spectra. The AS104 had significantly (P<0.0001) higher average plasma flow rates (F:53 vs. S:44 ml/minute), plasma collection efficiency (F:90 vs. S:69%), and platelet loss (F:2.0 vs. S:0.14 x 10(11) plt) than Spectra. Platelet loss correlated with inlet flow rate with the AS104 but not with the Spectra. The AS104 has a significantly higher collection efficiency than Spectra allowing it to remove the same amount of plasma in significantly less time, by processing significantly less blood, using significantly less AC, but removing significantly more platelets than Spectra. Copyright 2001 Wiley-Liss, Inc.

Status of Standardization Projects

DTIC Science & Technology

1992-09-30

0872 ANSIZ83 14 GAS FD SV EQ COUNTER APPLI GL G5 B 912 921 922 A GL YD 99 GS U B 7320 0874 A A XXX CABINET DOUGH PRF 18 PAN CAP GL 84 A 914 931 931 A GL...N D 7320 0897 MIL-D-2467F DOUGH ROLLING MACHINES PIE YD H5 924 934 934 A YD 99 N 7320 0898 0O-D-2813 DOUGH ROLLING MACHINES PIE YD 84 924 934 934 A...934 934 A GL SA 50 SS N 8920 0551 MIL-F-44279GL FRUIT BARS OPER RAT COMP GL F2 924 934 934 A GL SA 50 SS N 8920 0552 MIL-O-44136B OATMEAL COOKIE AND

Status of Standardization Projects

DTIC Science & Technology

1993-06-30

904 914 933 A GL 99 GS U 0 7320 0872 ANSIZ83 14 GAS FD SV EQ COUNTER APPLI GL GS B 912 921 932 A GL YDV 99 CS U B 7320 0874 A A XXX CABINET DOUGH PRF...YT YT T RT S D 7320 0897 MIL-D-2467F DOUGH ROLLING MACHINES PIE YDI H5 924 934 933 G VD1 99 U 7320 0898 00-0-2813 DOUGH ROLLING M4ACHINES PIE YD1 84...NOT 1 DOUGH TROUGHS GL H5 932 941 941 A GL VDI 99 8S N 7320 0906 NIL-D-2471D DOUGH DIVIDING MACHINE GL HS 931 941 941 A GL VOl 99 GS N 7320 0907 MIL-B

Status of Standardization Projects

DTIC Science & Technology

1993-03-31

XXX CABINET DOUGH PRF 18 PAN CAP GL B4 A 914 931 932 A GL YD 99 GS U B 7320 0875 A A XXX VEGETABLE CUT AND SL MACH GL B4 A 914 931 932 A GL YD 99 GS... DOUGH ROLLING MACHINES PIE YD H5 924 934 934 A YD 99 N 7320 0898 OO-D-2813 DOUGH ROLLING MACHINES PIE YD B4 924 934 934 A YO 99 N 7320 0899 A-A-50109...0903 A-A-XXX VEGETABLE PEELING MACHINE ELEC GL B4 A 931 934 934 A GL YD 99 GS N 7320 0904 MIL-D-13053D NOT 1 DOUGH TROUGHS GL H5 932 941 941 A GL YD 99

Enlarging the Societal Pie Through Wise Legislation: A Psychological Perspective.

PubMed

Baron, Jonathan; Bazerman, Max H; Shonk, Katherine

2006-06-01

We offer a psychological perspective to explain the failure of governments to create near-Pareto improvements. Our tools for analyzing these failures reflect the difficulties people have trading small losses for large gains: the fixed-pie approach to negotiations, the omission bias and status quo bias, parochialism and dysfunctional competition, and the neglect of secondary effects. We examine the role of human judgment in the failure to find wise trade-offs by discussing diverse applications of citizen and government decision making, including AIDS treatment, organ-donation systems, endangered-species protection, subsidies, and free trade. Our overall goal is to offer a psychological approach for understanding suboptimality in government decision making. © 2006 Association for Psychological Science.

Efficient and optimized identification of generalized Maxwell viscoelastic relaxation spectra

PubMed Central

Babaei, Behzad; Davarian, Ali; Pryse, Kenneth M.; Elson, Elliot L.; Genin, Guy M.

2017-01-01

Viscoelastic relaxation spectra are essential for predicting and interpreting the mechanical responses of materials and structures. For biological tissues, these spectra must usually be estimated from viscoelastic relaxation tests. Interpreting viscoelastic relaxation tests is challenging because the inverse problem is expensive computationally. We present here an efficient algorithm that enables rapid identification of viscoelastic relaxation spectra. The algorithm was tested against trial data to characterize its robustness and identify its limitations and strengths. The algorithm was then applied to identify the viscoelastic response of reconstituted collagen, revealing an extensive distribution of viscoelastic time constants. PMID:26523785

Monte Carlo treatment of resonance-radiation imprisonment in fluorescent lamps—revisited

NASA Astrophysics Data System (ADS)

Anderson, James B.

2016-12-01

We reported in 1985 a Monte Carlo treatment of the imprisonment of the 253.7 nm resonance radiation from mercury in the mercury-argon discharge of fluorescent lamps. The calculated spectra of the emitted radiation were found in good agreement with measured spectra. The addition of the isotope mercury-196 to natural mercury was found, also in agreement with experiments, to increase lamp efficiency. In this paper we report the extension of the earlier work with increased accuracy, analysis of photon exit-time distributions, recycling of energy released in quenching, analysis of dynamic similarity for different lamp sizes, variation of Mrozowski transfer rates, prediction and analysis of the hyperfine ultra-violet spectra, and optimization of tailored mercury isotope mixtures for increased lamp efficiency. The spectra were found insensitive to the extent of quenching and recycling. The optimized mixtures were found to increase efficiencies by as much as 5% for several lamp configurations. Optimization without increasing the mercury-196 fraction was found to increase efficiencies by nearly 1% for several configurations.

Associations of leisure-time physical activity with balance and lower extremity strength: a validation of the neuromuscular part of the Physical Activity Pie.

PubMed

Lindström, Paula J; Suni, Jaana H; Nygård, Clas-Håkan

2009-07-01

The importance of neuromuscular-type exercise (NME) has been recognized in recent recommendations for public health. However, the knowledge on associations and dose response of different types of leisure-time physical activity (LTPA) with musculoskeletal fitness and health is incomplete. This study evaluated the validity of the NME recommendation for public health introduced by the Physical Activity Pie. Engagement in LTPA and health-related fitness were assessed in 2 consecutive studies with the same adult population age 30 to 69 years (n = 575). Cross-sectional associations between different LTPA types and motor and musculoskeletal fitness were examined by logistic-regression models. Engagement in NME was associated with good static and dynamic balance and lower extremity strength. The highest odds ratios (OR) were found between brisk NME and static balance (most vs least fit OR = 2.39, moderate vs least fit OR = 1.94) and brisk NME and leg strength (more vs least fit OR = 2.10). Some associations were also found between brisk aerobic exercise and good balance. This cross-sectional study suggests that the recommendation for NME in the Physical Activity Pie is valid in terms of balance and leg strength, the 2 major fitness factors related to mobility functioning, especially among aging adults.

Diversity of the TLR4 Immunity Receptor in Czech Native Cattle Breeds Revealed Using the Pacific Biosciences Sequencing Platform.

PubMed

Novák, Karel; Pikousová, Jitka; Czerneková, Vladimíra; Mátlová, Věra

2017-07-03

The allelic variants of immunity genes in historical breeds likely reflect local infection pressure and therefore represent a reservoir for breeding. Screening to determine the diversity of the Toll-like receptor gene TLR4 was conducted in two conserved cattle breeds: Czech Red and Czech Red Pied. High-throughput sequencing of pooled PCR amplicons using the PacBio platform revealed polymorphisms, which were subsequently confirmed via genotyping techniques. Eight SNPs found in coding and adjacent regions were grouped into 18 haplotypes, representing a significant portion of the known diversity in the global breed panel and presumably exceeding diversity in production populations. Notably, the ancient Czech Red breed appeared to possess greater haplotype diversity than the Czech Red Pied breed, a Simmental variant, although the haplotype frequencies might have been distorted by significant crossbreeding and bottlenecks in the history of Czech Red cattle. The differences in haplotype frequencies validated the phenotypic distinctness of the local breeds. Due to the availability of Czech Red Pied production herds, the effect of intensive breeding on TLR diversity can be evaluated in this model. The advantages of the Pacific Biosciences technology for the resequencing of long PCR fragments with subsequent direct phasing were independently validated.

Females discriminate against heterospecific sperm in a natural hybrid zone.

PubMed

Cramer, Emily R A; Ålund, Murielle; McFarlane, S Eryn; Johnsen, Arild; Qvarnström, Anna

2016-08-01

When hybridization is maladaptive, species-specific mate preferences are selectively favored, but low mate availability may constrain species-assortative pairing. Females paired to heterospecifics may then benefit by copulating with multiple males and subsequently favoring sperm of conspecifics. Whether such mechanisms for biasing paternity toward conspecifics act as important reproductive barriers in socially monogamous vertebrate species remains to be determined. We use a combination of long-term breeding records from a natural hybrid zone between collared and pied flycatchers (Ficedula albicollis and F. hypoleuca), and an in vitro experiment comparing conspecific and heterospecific sperm performance in female reproductive tract fluid, to evaluate the potential significance of female cryptic choice. We show that the females most at risk of hybridizing (pied flycatchers) frequently copulate with multiple males and are able to inhibit heterospecific sperm performance. The negative effect on heterospecific sperm performance was strongest in pied flycatcher females that were most likely to have been previously exposed to collared flycatcher sperm. We thus demonstrate that a reproductive barrier acts after copulation but before fertilization in a socially monogamous vertebrate. While the evolutionary history of this barrier is unknown, our results imply that there is opportunity for it to be accentuated via a reinforcement-like process. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

Efficient and optimized identification of generalized Maxwell viscoelastic relaxation spectra.

PubMed

Babaei, Behzad; Davarian, Ali; Pryse, Kenneth M; Elson, Elliot L; Genin, Guy M

2015-03-01

Viscoelastic relaxation spectra are essential for predicting and interpreting the mechanical responses of materials and structures. For biological tissues, these spectra must usually be estimated from viscoelastic relaxation tests. Interpreting viscoelastic relaxation tests is challenging because the inverse problem is expensive computationally. We present here an efficient algorithm that enables rapid identification of viscoelastic relaxation spectra. The algorithm was tested against trial data to characterize its robustness and identify its limitations and strengths. The algorithm was then applied to identify the viscoelastic response of reconstituted collagen, revealing an extensive distribution of viscoelastic time constants. Copyright © 2015 Elsevier Ltd. All rights reserved.

Reference spectra of important adsorbed organic and inorganic phosphate binding forms for soil P speciation using synchrotron-based K-edge XANES spectroscopy.

PubMed

Prietzel, Jörg; Harrington, Gertraud; Häusler, Werner; Heister, Katja; Werner, Florian; Klysubun, Wantana

2016-03-01

Direct speciation of soil phosphorus (P) by linear combination fitting (LCF) of P K-edge XANES spectra requires a standard set of spectra representing all major P species supposed to be present in the investigated soil. Here, available spectra of free- and cation-bound inositol hexakisphosphate (IHP), representing organic P, and of Fe, Al and Ca phosphate minerals are supplemented with spectra of adsorbed P binding forms. First, various soil constituents assumed to be potentially relevant for P sorption were compared with respect to their retention efficiency for orthophosphate and IHP at P levels typical for soils. Then, P K-edge XANES spectra for orthophosphate and IHP retained by the most relevant constituents were acquired. The spectra were compared with each other as well as with spectra of Ca, Al or Fe orthophosphate and IHP precipitates. Orthophosphate and IHP were retained particularly efficiently by ferrihydrite, boehmite, Al-saturated montmorillonite and Al-saturated soil organic matter (SOM), but far less efficiently by hematite, Ca-saturated montmorillonite and Ca-saturated SOM. P retention by dolomite was negligible. Calcite retained a large portion of the applied IHP, but no orthophosphate. The respective P K-edge XANES spectra of orthophosphate and IHP adsorbed to ferrihydrite, boehmite, Al-saturated montmorillonite and Al-saturated SOM differ from each other. They also are different from the spectra of amorphous FePO4, amorphous or crystalline AlPO4, Ca phosphates and free IHP. Inclusion of reference spectra of orthophosphate as well as IHP adsorbed to P-retaining soil minerals in addition to spectra of free or cation-bound IHP, AlPO4, FePO4 and Ca phosphate minerals in linear combination fitting exercises results in improved fit quality and a more realistic soil P speciation. A standard set of P K-edge XANES spectra of the most relevant adsorbed P binding forms in soils is presented.

Vacuum-Ultraviolet photoionization studies of the microhydrationof DNA bases (Guanine, Cytosine, Adenine and Thymine)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Belau, L.; Wilson, K.R.; Leone, S.R.

2007-01-22

In this work, we report on a photoionization study of the microhydration of the four DNA bases. Gas-phase clusters of water with DNA bases [guanine (G), cytosine (C), adenine (A), and thymine (T)] are generated via thermal vaporization of the bases and expansion of the resultant vapor in a continuous supersonic jet expansion of water seeded in Ar. The resulting clusters are investigated by single-photon ionization with tunable vacuum-ultraviolet synchrotron radiation and mass analyzed using reflectron mass spectrometry. Photoionization efficiency (PIE) curves are recorded for the DNA bases and the following water (W) clusters: G, GW{sub n} (n = 1-3);more » C, CW{sub n} (n = 1-3); A, AW{sub n} (n = 1,2); and T, TW{sub n} (n = 1-3). Appearance energies (AE) are derived from the onset of these PIE curves (all energies in eV): G (8.1 {+-} 0.1), GW (8.0 {+-} 0.1), GW{sub 2} (8.0 {+-} 0.1), and GW{sub 3} (8.0); C (8.65 {+-} 0.05), CW (8.45 {+-} 0.05), CW{sub 2} (8.4 {+-} 0.1), and CW{sub 3} (8.3 {+-} 0.1); A (8.30 {+-} 0.05), AW (8.20 {+-} 0.05), and AW{sub 2} (8.1 {+-} 0.1); T (8.90 {+-} 0.05); and TW (8.75 {+-} 0.05), TW{sub 2} (8.6 {+-} 0.1), and TW{sub 3} (8.6 {+-} 0.1). The AEs of the DNA bases decrease slightly with the addition of water molecules (up to three) but do not converge to values found for photoinduced electron removal from DNA bases in solution.« less

Status of Standardization Projects, Quarter Ending 31 December 1992

DTIC Science & Technology

1992-12-31

B 7320 0872 ANSIZ83 14 GAS FD SV EQ COUNTER APPLI GL G5 B 912 921 922 A GL YD 99 GS U B 7320 0874 A A XXX CABINET DOUGH PRF 18 PAN CAP GL B4 A 914...YD 99 GS N CS 7320 0897 MIL-D-2467F DOUGH ROLLING MACHINES PIE YD H5 924 934 934 A YD 99 N 7320 0898 00-D-2813 DOUGH ROLLING MACHINES PIE YD B4 924...0552 MIL-0-44136B OATMEAL COOKIE AND GRA BARS GL F2 924 934 934 A GL SA 53 SS N 8920 0553 MIL-C-44112C CRACKERS FOR MEAL RTE GL F2 931 941 941 A GL SA

Arthroscopic pullout repair of posterior root tear of the medial meniscus: the anterior approach using medial collateral ligament pie-crusting release.

PubMed

Park, Young-Sik; Moon, Hong-Kyo; Koh, Yong-Gon; Kim, Yong-Chan; Sim, Dong-Sik; Jo, Seung-Bae; Kwon, Se-Kwang

2011-08-01

Posterior root tears of the medial meniscus are frequently encountered and should be repaired if possible to prevent osteoarthritis of the medial compartment. Various surgical techniques have been proposed to repair posterior root tears. The anterior arthroscopic approach can cause an iatrogenic chondral injury due to the narrow medial joint space. The posterior approaches might be technically unfamiliar to many surgeons because they require the establishment of a posteromedial or trans-septal portal. This paper describes the medial collateral ligament pie-crusting release technique for arthroscopic double transosseous pullout repair of posterior root tears of the medial meniscus through the anterior approach to provide the good visualization of the footprint and sufficient working space.

PhyloGeoViz: a web-based program that visualizes genetic data on maps.

PubMed

Tsai, Yi-Hsin E

2011-05-01

The first step of many population genetic studies is the simple visualization of allele frequencies on a landscape. This basic data exploration can be challenging without proprietary software, and the manual plotting of data is cumbersome and unfeasible at large sample sizes. I present an open source, web-based program that plots any kind of frequency or count data as pie charts in Google Maps (Google Inc., Mountain View, CA). Pie polygons are then exportable to Google Earth (Google Inc.), a free Geographic Information Systems platform. Import of genetic data into Google Earth allows phylogeographers access to a wealth of spatial information layers integral to forming hypotheses and understanding patterns in the data. © 2010 Blackwell Publishing Ltd.

Comparison of neutron spectra measured with three sizes of organic liquid scintillators using differentiation analysis

NASA Technical Reports Server (NTRS)

Shook, D. F.; Pierce, C. R.

1972-01-01

Proton recoil distributions were obtained by using organic liquid scintillators of different size. The measured distributions are converted to neutron spectra by differentiation analysis for comparison to the unfolded spectra of the largest scintillator. The approximations involved in the differentiation analysis are indicated to have small effects on the precision of neutron spectra measured with the smaller scintillators but introduce significant error for the largest scintillator. In the case of the smallest cylindrical scintillator, nominally 1.2 by 1.3 cm, the efficiency is shown to be insensitive to multiple scattering and to the angular distribution to the incident flux. These characteristics of the smaller scintillator make possible its use to measure scalar flux spectra within media high efficiency is not required.

Cherry-Slush-Candling Apparatus

NASA Technical Reports Server (NTRS)

Stephens, James B.; Weiss, James R.; Hoover, Gordon

1996-01-01

Proposed infrared-scanning apparatus for use in bakeries making cherry pies detect cherry pits remaining in cherry slush after pitting process. Pits detected via their relative opacity to infrared radiation.

Characterization of Active Dry Wine Yeast During Starter Culture (Pied de Cuve) Preparation for Sparkling Wine Production.

PubMed

Benucci, Ilaria; Liburdi, Katia; Cerreti, Martina; Esti, Marco

2016-08-01

The preparation of yeast starter culture (Pied de Cuve) for producing sparkling wine with the traditional method is a key factor for manufacturing a good Prise de mousse. In this paper, the evolution of total yeast population, its viability during Pied de Cuve preparation, and the pressure profile during the 2nd fermentation in 2 different base wines made from Bombino bianco and Chardonnay grapes were investigated using 4 different commercial active dried yeasts. The study proves that despite the initial differences observed throughout the acclimatization phase, all the tested strains showed similar results on either the total population (from 8.2 × 10(7) cells/mL to 1.3 × 10(8) cells/mL) or cellular viability (from 70% to 84%). Independently from the base wine tested, the kinetic of sugar consumption was faster during the gradual acclimatization to the alcoholic medium (phase II) and slower during the preparation of starter culture in active growth phase (phase III). During both of these phases Saccharomyces cerevisiae bayanus Vitilevure DV10(®) (Station œnotechnique de Champagne) proved to have a higher sugar consumption rate than the other strains. During the Prise de mousse, S. cerevisiae bayanus Lalvin EC-1118(®) (Lallemand) reached the maximum pressure increase within time in both base wines. © 2016 Institute of Food Technologists®

Challenging Notions of Academic Entitlement and Its Rise among Liberal Arts College Students

PubMed Central

Lemke, Debra; Marx, Jeff; Dundes, Lauren

2017-01-01

To assess academic entitlement, we employed a repeated cross-sectional design to compare survey data from two systematic random samples collected eight years apart, in 2009 (n = 225) and 2017 (n = 159), at a small, private, mid-Atlantic liberal arts college. According to an entitlement scale (based on Greenberger et al., 2008), students were less likely to be entitled in 2017 (27%) than in 2009 (41%) (p = 0.02). In 2009, a higher proportion of males than females felt entitled (50% versus 34%, p = 0.05), a sex difference that disappeared by 2017. To explore academic entitlement further, we developed the “PIE” scale to measure the extent to which students believe “participation,” “improvement” and “effort” should help determine their course grades. Although the proportion of above average PIE scorers was stable from 2009 (36%) to 2017 (34%), in 2017, more females than males were above average on PIE (26% of males versus 44% of females, p = 0.02). PIE, or the desire for recognition of “academic sweat equity,” could reflect students’ support for a learning model that goes beyond mastery and is more developmental and process oriented. These data challenge common conceptions of what constitutes academic entitlement, the belief that it is rising, and suggest continued discussions of what factors should determine grades. PMID:29211021

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morgan, T.L.; George, W.E.; Hensley, W.K.

As part of the Hydrogeochemical and Stream Sediment Reconnaissance (HSSR) of the National Uranium Resource Evaluation (NURE) sponsored by the US Department of Energy (DOE), the Los Alamos Scientific Laboratory (LASL) conducted a detailed hydrogeochemical survey of well waters in a 4250-km/sup 2/ area near Pie Town in west-central New Mexico. A total of 300 well samples was collected and analyzed for uranium and 23 other elements. The results of these analyses and carbonate and bicarbonate ion concentrations are presented in the Appendixes of this report. Uranium concentrations range from below the detection limit of 0.02 parts per billion (ppB)more » to 293.18 ppB and average 8.71 ppB. Samples containing high levels of uranium were collected from the Largo Creek valley west of Quemado, from a small area about 6 km east of Quemado, from a small area surrounding Pie Town, and from scattered locations in the area surrounding Adams Diggings north of Pie Town. Most of the samples containing high uranium concentrations were collected from wells associated with the volcanic sedimentary facies of the Datil formation. This formation is a likely source of mobile uranium that may be precipitating in the underlying Baca formation, a known uranium host unit. Bicarbonate ion concentration, while proportional to uranium concentration in some cases, is not a strong controlling factor in the uranium concentrations in samples from this area.« less

Introducing a Framework for Physics Innovation and Entrepreneurship (PIE) Education

NASA Astrophysics Data System (ADS)

Roughani, Bahram

A desired outcome for Physics Innovation and Entrepreneurship (PIE) education is preparing physics majors with an innovative and entrepreneurial mindset who are capable of opportunity recognition and adept in leveraging physics knowledge to address specific needs. Physics as a discipline is well-recognized to prepare students who become problem solvers and critical thinkers, gifted in dealing with abstract ideas and ambiguities in the context of complex and real-world problems. These characteristics when enhanced through appropriate combinations of curricular, co-curricular, and extra-curricular programs can prepare physics majors for careers and future challenges that may involve translating physics knowledge into useful products and services either as part of a technical team within an organization or through startups. A viable PIE education model prepares graduates for various career paths in addition to the traditional options such as pursuing graduate studies or becoming a science teacher. Having a well-defined ``third option'' for physics will benefit the robustness of the physics discipline through recruitment and retention of prospective students who in principle are interested in physics as a subject, but in practice they may overlook physics as their preferred major primarily because they are uncertain about a viable career path based on an undergraduate physics education. The ''Pathways to Innovation'' at Loyola is established based on the program developed by VentureWell and Epicenter (NSF Supported).

Do performance and image enhancing drug users in regional Queensland experience difficulty accessing health services?

PubMed

Dunn, Matthew; Henshaw, Richard; McKay, Fiona H

2016-07-01

To understand health service access and needs of people who use performance and image enhancing drugs (PIED) in regional Queensland. Semi-structured interviews were conducted with 21 people (n = 19 men) who reported the use of a range of PIEDs, including anabolic-androgenic steroids, human chorionic gonadotropin, growth hormone, clenbuterol, tamoxifen, insulin and peptides. Participants reported accessing a range of services, including needle and syringe programs and pharmacies, for sterile injecting equipment. While PIEDs users attributed some stigma to needle and syringe programs, they were seen as an important service for injecting equipment. Participants reported receiving either positive care from health-care providers, such as general practitioners (GP), or having negative experiences due to the stigma attached with PIED use. Few participants reported disclosing their PIED use to their GP not only because of the concerns that their GP would no longer see them but also because they felt their GP was not knowledgeable about these substances. Participants in the study reported no difficulty in accessing health services based on living in a regional area, with their concern focused more upon how they were viewed and treated by service staff. [Dunn M, Henshaw R, Mckay F. H. Do performance and image enhancing drug users in regional Queensland experience difficulty accessing health services? Drug Alcohol Rev 2016;35:377-382]. © 2015 Australasian Professional Society on Alcohol and other Drugs.

A new broadly tunable (7.4-10.2 eV) laser based VUV light source and its first application to aerosol mass spectrometry

NASA Astrophysics Data System (ADS)

Hanna, S. J.; Campuzano-Jost, P.; Simpson, E. A.; Robb, D. B.; Burak, I.; Blades, M. W.; Hepburn, J. W.; Bertram, A. K.

2009-01-01

A laser based vacuum ultraviolet (VUV) light source using resonance enhanced four wave difference mixing in xenon gas was developed for near threshold ionization of organics in atmospheric aerosol particles. The source delivers high intensity pulses of VUV light (in the range of 1010 to 1013 photons/pulse depending on wavelength, 5 ns FWHM) with a continuously tunable wavelength from 122 nm (10.2 eV) to 168 nm (7.4 eV)E The setup allows for tight (<1 mm2) and precise focusing ([mu]rad pointing angle adjustability), attributes required for single particle detection. The generated VUV is separated from the pump wavelengths by a custom monochromator which ensures high spectral purity and minimizes absorptive losses. The performance of the source was characterized using organic molecules in the gas phase and optimal working conditions are reported. In the gas phase measurements, photoionization efficiency (PIE) curves were collected for seven different organic species with ionization energies spanning the full wavelength range of the VUV source. The measured appearance energies are very close to the literature values of the ionization energies for all seven species. The effectiveness of the source for single particle studies was demonstrated by analysis of individual caffeine aerosols vaporized by a pulsed CO2 laser in an ion trap mass spectrometer. Mass spectra from single particles down to 300 nm in diameter were collected. Excellent signal to noise characteristics for these small particles give a caffeine detection limit of 8 × 105 molecules which is equivalent to a single 75 nm aerosol, or approximately 1.5% of a 300 nm particleE The appearance energy of caffeine originating from the aerosol was also measured and found to be 7.91 ± 0.05 eV, in good agreement with literature values.

GlycoDeNovo - an Efficient Algorithm for Accurate de novo Glycan Topology Reconstruction from Tandem Mass Spectra

NASA Astrophysics Data System (ADS)

Hong, Pengyu; Sun, Hui; Sha, Long; Pu, Yi; Khatri, Kshitij; Yu, Xiang; Tang, Yang; Lin, Cheng

2017-08-01

A major challenge in glycomics is the characterization of complex glycan structures that are essential for understanding their diverse roles in many biological processes. We present a novel efficient computational approach, named GlycoDeNovo, for accurate elucidation of the glycan topologies from their tandem mass spectra. Given a spectrum, GlycoDeNovo first builds an interpretation-graph specifying how to interpret each peak using preceding interpreted peaks. It then reconstructs the topologies of peaks that contribute to interpreting the precursor ion. We theoretically prove that GlycoDeNovo is highly efficient. A major innovative feature added to GlycoDeNovo is a data-driven IonClassifier which can be used to effectively rank candidate topologies. IonClassifier is automatically learned from experimental spectra of known glycans to distinguish B- and C-type ions from all other ion types. Our results showed that GlycoDeNovo is robust and accurate for topology reconstruction of glycans from their tandem mass spectra. [Figure not available: see fulltext.

Schematic for efficient computation of GC, GC3, and AT3 bias spectra of genome

PubMed Central

Rizvi, Ahsan Z; Venu Gopal, T; Bhattacharya, C

2012-01-01

Selection of synonymous codons for an amino acid is biased in protein translation process. This biased selection causes repetition of synonymous codons in structural parts of genome that stands for high N/3 peaks in DNA spectrum. Period-3 spectral property is utilized here to produce a 3-phase network model based on polyphase filterbank concepts for derivation of codon bias spectra (CBS). Modification of parameters in this model can produce GC, GC3, and AT3 bias spectra. Complete schematic in LabVIEW platform is presented here for efficient and parallel computation of GC, GC3, and AT3 bias spectra of genomes alongwith results of CBS patterns. We have performed the correlation coefficient analysis of GC, GC3, and AT3 bias spectra with codon bias patterns of CBS for biological and statistical significance of this model. PMID:22368390

Schematic for efficient computation of GC, GC3, and AT3 bias spectra of genome.

PubMed

Rizvi, Ahsan Z; Venu Gopal, T; Bhattacharya, C

2012-01-01

Selection of synonymous codons for an amino acid is biased in protein translation process. This biased selection causes repetition of synonymous codons in structural parts of genome that stands for high N/3 peaks in DNA spectrum. Period-3 spectral property is utilized here to produce a 3-phase network model based on polyphase filterbank concepts for derivation of codon bias spectra (CBS). Modification of parameters in this model can produce GC, GC3, and AT3 bias spectra. Complete schematic in LabVIEW platform is presented here for efficient and parallel computation of GC, GC3, and AT3 bias spectra of genomes alongwith results of CBS patterns. We have performed the correlation coefficient analysis of GC, GC3, and AT3 bias spectra with codon bias patterns of CBS for biological and statistical significance of this model.

Signal Partitioning Algorithm for Highly Efficient Gaussian Mixture Modeling in Mass Spectrometry

PubMed Central

Polanski, Andrzej; Marczyk, Michal; Pietrowska, Monika; Widlak, Piotr; Polanska, Joanna

2015-01-01

Mixture - modeling of mass spectra is an approach with many potential applications including peak detection and quantification, smoothing, de-noising, feature extraction and spectral signal compression. However, existing algorithms do not allow for automated analyses of whole spectra. Therefore, despite highlighting potential advantages of mixture modeling of mass spectra of peptide/protein mixtures and some preliminary results presented in several papers, the mixture modeling approach was so far not developed to the stage enabling systematic comparisons with existing software packages for proteomic mass spectra analyses. In this paper we present an efficient algorithm for Gaussian mixture modeling of proteomic mass spectra of different types (e.g., MALDI-ToF profiling, MALDI-IMS). The main idea is automated partitioning of protein mass spectral signal into fragments. The obtained fragments are separately decomposed into Gaussian mixture models. The parameters of the mixture models of fragments are then aggregated to form the mixture model of the whole spectrum. We compare the elaborated algorithm to existing algorithms for peak detection and we demonstrate improvements of peak detection efficiency obtained by using Gaussian mixture modeling. We also show applications of the elaborated algorithm to real proteomic datasets of low and high resolution. PMID:26230717

Health service ignores what is known to work.

PubMed

1993-02-03

'Apple pie' marketing statements like 'Meeting Customers' Needs' and 'Putting Quality Services First' have been ridiculed by Professor Alan Maynard, Director of the Centre for Health Economics at York University.

Association of Parathyroid Gland Biopsy Excision Technique With Ex Vivo Radiation Counts During Radioguided Parathyroid Surgery

PubMed Central

Hinson, Andrew M.; Lawson, Bradley R.; Franco, Aime T.

2017-01-01

Importance Parathyroid biopsy represents a means for normal and hyperfunctional glands to be distinguished intraoperatively. However, no data exist to guide surgeons regarding how much of a parathyroid gland must be biopsied to satisfy the 20% rule. Objective To quantify the relative proportion of a hyperfunctional parathyroid gland that must be evaluated with the gamma probe to satisfy the 20% rule. Design, Setting, and Participants A retrospective review of surgical data for 24 consecutive patients (16 women, 18 men; mean [SD] age, 66.6 [10] years; range, 51-83 years) who underwent surgery for primary hyperparathyroidism between May and October, 2015, in a tertieary academic medical center. Main Outcomes and Measures Extirpated parathyroid glands were sectioned into parallel or pie-shaped biopsies and evaluated ex vivo with a gamma probe to determine what percentage of a hyperfunctional gland must be sampled to meet the Norman 20% rule. The hypothesis was formulated during data collection. Results In total, 253 ex vivo biopsy specimens were obtained from 33 surgically removed parathyroid glands. Parathyroid biopsies satisfied the 20% rule with an accuracy that depended on the relative proportion of the parent gland represented: half or more (96.6%; 95% CI, 91.7%-100.0%), a quarter to one-half (87.0%; 95% CI, 79.3%-94.7%), less than a quarter (63.6%; 95% CI, 54.5%-72.8%). When less than a quarter of the gland was removed, pie-shaped biopsies were more likely to satisfy the 20% rule compared with parallel biopsies of the same weight (78.4% vs 56.2%; absolute difference, 22.2%; 95% CI, 4.7%-39.7%). Conclusions and Relevance Unless half of a parathyroid gland is biopsied during radioguided parathyroidectomy, the 20% rule cannot reliably rule out the presence of a hyperfunctional parathyroid lesion. Pie-shaped biopsies originating from the center of the gland are associated with a lower rate of false-negative results compared with peripheral biopsies of similar size. Pie-shaped biopsies and biopsy of half or more of each nonexcised parathyroid gland for ex vivo counts may increase the risk of remnant devascularization and resultant hypoparathyroidism. PMID:28358958

Association of Parathyroid Gland Biopsy Excision Technique With Ex Vivo Radiation Counts During Radioguided Parathyroid Surgery.

PubMed

Hinson, Andrew M; Lawson, Bradley R; Franco, Aime T; Stack, Brendan C

2017-06-01

Parathyroid biopsy represents a means for normal and hyperfunctional glands to be distinguished intraoperatively. However, no data exist to guide surgeons regarding how much of a parathyroid gland must be biopsied to satisfy the 20% rule. To quantify the relative proportion of a hyperfunctional parathyroid gland that must be evaluated with the gamma probe to satisfy the 20% rule. A retrospective review of surgical data for 24 consecutive patients (16 women, 18 men; mean [SD] age, 66.6 [10] years; range, 51-83 years) who underwent surgery for primary hyperparathyroidism between May and October, 2015, in a tertieary academic medical center. Extirpated parathyroid glands were sectioned into parallel or pie-shaped biopsies and evaluated ex vivo with a gamma probe to determine what percentage of a hyperfunctional gland must be sampled to meet the Norman 20% rule. The hypothesis was formulated during data collection. In total, 253 ex vivo biopsy specimens were obtained from 33 surgically removed parathyroid glands. Parathyroid biopsies satisfied the 20% rule with an accuracy that depended on the relative proportion of the parent gland represented: half or more (96.6%; 95% CI, 91.7%-100.0%), a quarter to one-half (87.0%; 95% CI, 79.3%-94.7%), less than a quarter (63.6%; 95% CI, 54.5%-72.8%). When less than a quarter of the gland was removed, pie-shaped biopsies were more likely to satisfy the 20% rule compared with parallel biopsies of the same weight (78.4% vs 56.2%; absolute difference, 22.2%; 95% CI, 4.7%-39.7%). Unless half of a parathyroid gland is biopsied during radioguided parathyroidectomy, the 20% rule cannot reliably rule out the presence of a hyperfunctional parathyroid lesion. Pie-shaped biopsies originating from the center of the gland are associated with a lower rate of false-negative results compared with peripheral biopsies of similar size. Pie-shaped biopsies and biopsy of half or more of each nonexcised parathyroid gland for ex vivo counts may increase the risk of remnant devascularization and resultant hypoparathyroidism.

Predictive models attribute effects on fish assemblages to toxicity and habitat alteration.

PubMed

de Zwart, Dick; Dyer, Scott D; Posthuma, Leo; Hawkins, Charles P

2006-08-01

Biological assessments should both estimate the condition of a biological resource (magnitude of alteration) and provide environmental managers with a diagnosis of the potential causes of impairment. Although methods of quantifying condition are well developed, identifying and proportionately attributing impairment to probable causes remain problematic. Furthermore, analyses of both condition and cause have often been difficult to communicate. We developed an approach that (1) links fish, habitat, and chemistry data collected from hundreds of sites in Ohio (USA) streams, (2) assesses the biological condition at each site, (3) attributes impairment to multiple probable causes, and (4) provides the results of the analyses in simple-to-interpret pie charts. The data set was managed using a geographic information system. Biological condition was assessed using a RIVPACS (river invertebrate prediction and classification system)-like predictive model. The model provided probabilities of capture for 117 fish species based on the geographic location of sites and local habitat descriptors. Impaired biological condition was defined as the proportion of those native species predicted to occur at a site that were observed. The potential toxic effects of exposure to mixtures of contaminants were estimated using species sensitivity distributions and mixture toxicity principles. Generalized linear regression models described species abundance as a function of habitat characteristics. Statistically linking biological condition, habitat characteristics including mixture risks, and species abundance allowed us to evaluate the losses of species with environmental conditions. Results were mapped as simple effect and probable-cause pie charts (EPC pie diagrams), with pie sizes corresponding to magnitude of local impairment, and slice sizes to the relative probable contributions of different stressors. The types of models we used have been successfully applied in ecology and ecotoxicology, but they have not previously been used in concert to quantify impairment and its likely causes. Although data limitations constrained our ability to examine complex interactions between stressors and species, the direct relationships we detected likely represent conservative estimates of stressor contributions to local impairment. Future refinements of the general approach and specific methods described here should yield even more promising results.

The Pied Pipers of Poetry.

ERIC Educational Resources Information Center

Hildebrand, Verna; Hines, Rebecca P.

1981-01-01

Indicates benefits of introducing poetry to young children. Introduces poetry that is based on subjects and experiences familiar to children such as galoshes, mittens, snowmen, animals, and the sensation of mud between toes. (Author/RH)

Identification, quantification, spatiotemporal distribution and genetic variation of major latex secondary metabolites in the common dandelion (Taraxacum officinale agg.).

PubMed

Huber, Meret; Triebwasser-Freese, Daniella; Reichelt, Michael; Heiling, Sven; Paetz, Christian; Chandran, Jima N; Bartram, Stefan; Schneider, Bernd; Gershenzon, Jonathan; Erb, Matthias

2015-07-01

The secondary metabolites in the roots, leaves and flowers of the common dandelion (Taraxacum officinale agg.) have been studied in detail. However, little is known about the specific constituents of the plant's highly specialized laticifer cells. Using a combination of liquid and gas chromatography, mass spectrometry and nuclear magnetic resonance spectrometry, we identified and quantified the major secondary metabolites in the latex of different organs across different growth stages in three genotypes, and tested the activity of the metabolites against the generalist root herbivore Diabrotica balteata. We found that common dandelion latex is dominated by three classes of secondary metabolites: phenolic inositol esters (PIEs), triterpene acetates (TritAc) and the sesquiterpene lactone taraxinic acid β-D-glucopyranosyl ester (TA-G). Purification and absolute quantification revealed concentrations in the upper mgg(-1) range for all compound classes with up to 6% PIEs, 5% TritAc and 7% TA-G per gram latex fresh weight. Contrary to typical secondary metabolite patterns, concentrations of all three classes increased with plant age. The highest concentrations were measured in the main root. PIE profiles differed both quantitatively and qualitatively between plant genotypes, whereas TritAc and TA-G differed only quantitatively. Metabolite concentrations were positively correlated within and between the different compound classes, indicating tight biosynthetic co-regulation. Latex metabolite extracts strongly repelled D. balteata larvae, suggesting that the latex constituents are biologically active. Copyright © 2015 Elsevier Ltd. All rights reserved.

Evolution of the genetic variability of eight French dairy cattle breeds assessed by pedigree analysis.

PubMed

Danchin-Burge, C; Leroy, G; Brochard, M; Moureaux, S; Verrier, E

2012-06-01

A pedigree analysis was performed on eight French dairy cattle breeds to assess their change in genetic variability since a first analysis completed in 1996. The Holstein, Normande and Montbéliarde breeds are selected internationally with over hundreds of thousands cows registered in the performance recording system. Three breeds are internationally selected but with limited numbers of cows in France (Brown Swiss, French Simmental and French Red Pied). The last two remaining breeds (Abondance and Tarentaise) are raised at regional level. The effective numbers of ancestors of cows born between 2004 and 2007 varied between 15 (Abondance and Tarentaise) and 51 (French Red Pied). The effective population sizes (classical approach) varied between 53 (Abondance) and 197 (French Red Pied). This article also compares the genetic variability of the ex situ (collections of the French National Cryobank) and in situ populations. The results were commented in regard to the recent history of gene flows in the different breeds as well as the existence of more or less stringent bottlenecks. Our results showed that whatever the size of the breeds, their genetic diversity impoverished quite rapidly since 1996 and they all could be considered as quite poor from a genetic diversity point of view. It shows the need for setting up cryobanks as gene reservoirs as well as sustainable breeding programmes that include loss of genetic diversity as an integrated control parameter. © 2011 Blackwell Verlag GmbH.

Effect of format on comprehension of adherence data in chronic disease: A cross-sectional study in HIV.

PubMed

Lyons, Anita; Bilker, Warren B; Hines, Janet; Gross, Robert

2016-01-01

To determine which formats communicate medication adherence effectively to patients. HIV-infected adults on antiretrovirals viewed examples of refill data in 5 formats: (1) percentage of doses, (2) number of days late to refill ("days late"), (3) calendar of days with/without medications, (4) pie chart of days with/without medications, and (5) letter grade. Five scenarios (>95%, 90-95%, <90%, <80% and <70% adherence) were presented in each format. Participants rated scenarios on adherence improvement needed. "Good understanding" was ≥ 4 of 5 scenarios correct. We calculated odds ratios for "good understanding" using logistic regression with percentage as the referent format. 124 participants were median age 48.5 years, 65% Black, 71% male. Understanding of all formats differed by education (all interaction p values<0.02). For ≤ 12 years education, odds ratios (OR) of understanding (95% CI) compared to percentage were: days late 3.3 (2.3-4.7), calendar 3.1 (2.2-4.3) pie chart 2.0 (1.4-2.7), and letter grade 1.8 (1.3-2.5). For >12 years education, ORs were: days late 1.3 (0.9-2.0), calendar 2.4 (1.5-3.8), pie chart 2.9 (1.8-4.6), and letter grade 1.7 (1.1-2.6). Calendar plot was most preferred. Adherence percentage was the least understood format regardless of education. Calendars should be used to convey adherence information. Published by Elsevier Ireland Ltd.

Differences in foot self-care and lifestyle between men and women with diabetes mellitus.

PubMed

Rossaneis, Mariana Angela; Haddad, Maria do Carmo Fernandez Lourenço; Mathias, Thaís Aidar de Freitas; Marcon, Sonia Silva

2016-08-15

to investigate differences with regard to foot self-care and lifestyle between men and women with diabetes mellitus. cross-sectional study conducted in a sample of 1,515 individuals with diabetes mellitus aged 40 years old or older. Poisson regression models were used to identity differences in foot self-care deficit and lifestyle between sexes, adjusting for socioeconomic and clinical characteristics, smoking and alcohol consumption. foot self-care deficit, characterized by not regularly drying between toes; not regularly checking feet; walking barefoot; poor hygiene and inappropriately trimmed nails, was significantly higher among men, though men presented a lower prevalence of feet scaling and use of inappropriate shoes when compared to women. With regard to lifestyle, men presented less healthy habits, such as not adhering to a proper diet and taking laboratory exams to check for lipid profile at the frequency recommended. the nursing team should take into account gender differences concerning foot self-care and lifestyle when implementing educational activities and interventions intended to decrease risk factors for foot ulceration. investigar as diferenças no autocuidado com os pés e no estilo de vida entre mulheres e homens diabéticos. estudo transversal realizado com uma amostra de 1.515 diabéticos com 40 anos ou mais. Foram utilizados modelos de regressão de Poisson para identificar diferenças entre os sexos na prevalência de déficit de autocuidado com os pés e no estilo de vida, ajustando-se por características socioeconômicas, clínicas, tabagismo e alcoolismo. a prevalência de déficit de autocuidado com os pés, caracterizada por baixa frequência de secagem dos espaços interdigitais; da não avaliação periódica dos pés; do hábito de andar descalço; de higiene insatisfatória e corte inadequado de unhas foi significativamente maior entre os homens. Contudo, eles apresentaram menor prevalência na prática de escaldar os pés e no uso de calçados inadequados em comparação às mulheres. Em relação ao estilo de vida, os homens também apresentaram comportamentos menos saudáveis pois tem significativamente menor controle alimentar e não realizam os exames laboratoriais referentes ao perfil lipídico na frequência recomendada. considerar as diferenças de gênero no autocuidado com os pés e no estilo de vida permite à equipe de enfermagem direcionar atividades educacionais e intervenções nos fatores de risco à ulceração dos pés. investigar las diferencias en el autocuidado de los pies y estilo de vida entre mujeres y hombres diabéticos. estudio transversal realizado con una muestra de 1.515 diabéticos con 40 años o más. Fueron utilizados los modelos de regresión de Poisson para identificar diferencias entre los sexos en la prevalencia de déficit de autocuidado de los pies y estilo de vida, ajustándolas por características socioeconómicas, clínicas, tabaquismo y alcoholismo. la prevalencia de déficit de autocuidado de los pies, caracterizada por: baja frecuencia de secado de los espacios interdigitales; falta de evaluación periódica de los pies; hábito de andar descalzo; higiene insatisfactoria; y, corte inadecuado de uñas, fue significativamente mayor entre los hombre. Sin embargo, estos presentaron menor prevalencia en la práctica de escaldar los pies y en el uso de calzados inadecuados en comparación a las mujeres. En relación al estilo de vida, los hombres también presentaron comportamientos menos saludables ya que tienen significativamente menor control alimentario y no realizan los exámenes de laboratorio referentes al perfil lipídico, con la frecuencia recomendada. considerar las diferencias de género en el autocuidado de los pies y en el estilo de vida, le permite al equipo de enfermería realizar actividades educacionales e intervenciones en los factores de riesgo para la ulceración de los pies.

Improving the accuracy and efficiency of time-resolved electronic spectra calculations: cellular dephasing representation with a prefactor.

PubMed

Zambrano, Eduardo; Šulc, Miroslav; Vaníček, Jiří

2013-08-07

Time-resolved electronic spectra can be obtained as the Fourier transform of a special type of time correlation function known as fidelity amplitude, which, in turn, can be evaluated approximately and efficiently with the dephasing representation. Here we improve both the accuracy of this approximation-with an amplitude correction derived from the phase-space propagator-and its efficiency-with an improved cellular scheme employing inverse Weierstrass transform and optimal scaling of the cell size. We demonstrate the advantages of the new methodology by computing dispersed time-resolved stimulated emission spectra in the harmonic potential, pyrazine, and the NCO molecule. In contrast, we show that in strongly chaotic systems such as the quartic oscillator the original dephasing representation is more appropriate than either the cellular or prefactor-corrected methods.

A Toolkit for Eye Recognition of LAMOST Spectroscopy

NASA Astrophysics Data System (ADS)

Yuan, H.; Zhang, H.; Zhang, Y.; Lei, Y.; Dong, Y.; Zhao, Y.

2014-05-01

The Large sky Area Multi-Object fiber Spectroscopic Telescope (LAMOST, also named the Guo Shou Jing Telescope) has finished the pilot survey and now begun the normal survey by the end of 2012 September. There have already been millions of targets observed, including thousands of quasar candidates. Because of the difficulty in the automatic identification of quasar spectra, eye recognition is always necessary and efficient. However massive spectra identification by eye is a huge job. In order to improve the efficiency and effectiveness of spectra , a toolkit for eye recognition of LAMOST spectroscopy is developed. Spectral cross-correlation templates from the Sloan Digital Sky Survey (SDSS) are applied as references, including O star, O/B transition star, B star, A star, F/A transition star, F star, G star, K star, M1 star, M3 star,M5 star,M8 star, L1 star, magnetic white dwarf, carbon star, white dwarf, B white dwarf, low metallicity K sub-dwarf, "Early-type" galaxy, galaxy, "Later-type" galaxy, Luminous Red Galaxy, QSO, QSO with some BAL activity and High-luminosity QSO. By adjusting the redshift and flux ratio of the template spectra in an interactive graphic interface, the spectral type of the target can be discriminated in a easy and feasible way and the redshift is estimated at the same time with a precision of about millesimal. The advantage of the tool in dealing with low quality spectra is indicated. Spectra from the Pilot Survey of LAMSOT are applied as examples and spectra from SDSS are also tested from comparison. Target spectra in both image format and fits format are supported. For convenience several spectra accessing manners are provided. All the spectra from LAMOST pilot survey can be located and acquired via the VOTable files on the internet as suggested by International Virtual Observatory Alliance (IVOA). After the construction of the Simple Spectral Access Protocol (SSAP) service by the Chinese Astronomical Data Center (CAsDC), spectra can be obtained and analyzed in a more efficient way.

Getting Your Share of the Budget Pie.

ERIC Educational Resources Information Center

Alford, Cynthia; Kibbey, Marsha

1992-01-01

Presents guidelines for securing funding from the school administration for library automation projects, including suggestions on researching technology and writing a proposal. A sidebar offers advice on approaching corporations for funding for school library automation. (MES)

In vivo Raman spectroscopy for oral cancers diagnosis

NASA Astrophysics Data System (ADS)

Singh, S. P.; Deshmukh, Atul; Chaturvedi, Pankaj; Krishna, C. Murali

2012-01-01

Oral squamous cell carcinoma is sixth among the major malignancies worldwide. Tobacco habits are known as major causative factor in tumor carcinogenesis in oral cancer. Optical spectroscopy methods, including Raman, are being actively pursued as alternative/adjunct for cancer diagnosis. Earlier studies have demonstrated the feasibility of classifying normal, premalignant and malignant oral ex-vivo tissues. In the present study we have recorded in vivo spectra from contralateral normal and diseased sites of 50 subjects with pathologically confirmed lesions of buccal mucosa using fiber-optic-probe-coupled HE-785 Raman spectrometer. Spectra were recorded on similar points as per teeth positions with an average acquisition time of 8 seconds. A total of 215 and 225 spectra from normal and tumor sites, respectively, were recorded. Finger print region (1200-1800 cm-1) was utilized for classification using LDA. Standard-model was developed using 125 normal and 139 tumor spectra from 27 subjects. Two separate clusters with an efficiency of ~95% were obtained. Cross-validation with leave-one-out yielded ~90% efficiency. Remaining 90 normal and 86 tumor spectra were used as test data and predication efficiency of model was evaluated. Findings of the study indicate that Raman spectroscopic methods in combination with appropriate multivariate tool can be used for objective, noninvasive and rapid diagnosis.

Determination of photoionization cross-sections of different organic molecules using gas chromatography coupled to single-photon ionization (SPI) time-of-flight mass spectrometry (TOF-MS) with an electron-beam-pumped rare gas excimer light source (EBEL): influence of molecular structure and analytical implications.

PubMed

Eschner, Markus S; Zimmermann, Ralf

2011-07-01

This work describes a fast and reliable method for determination of photoionization cross-sections (PICS) by means of gas chromatography (GC) coupled to single-photon ionization mass spectrometry (SPI-MS). Photoionization efficiency (PIE) data for 69 substances was obtained at a photon energy of 9.8 ± 0.4 eV using an innovative electron-beam-pumped rare gas excimer light source (EBEL) filled with argon. The investigated analytes comprise 12 alkylbenzenes as well as 11 other substituted benzenes, 23 n-alkanes, ten polyaromatic hydrocarbons, seven aromatic heterocycles, and six polyaromatic heterocycles. Absolute PICS for each substance at 9.8 eV are calculated from the relative photoionization efficiencies of the compounds with respect to benzene, whose photoionization cross-section data is well known. Furthermore, a direct correlation between the type of benzene substituents and their absolute PICS is presented and discussed in depth. Finally, comparison of previously measured photoionization cross-sections for 20 substances shows good agreement with the data of the present work.

A study on the coagulation of polycyclic aromatic hydrocarbon clusters to determine their collision efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raj, Abhijeet; Sander, Markus; Janardhanan, Vinod

2010-03-15

This paper presents a theoretical study on the physical interaction between polycyclic aromatic hydrocarbons (PAHs) and their clusters of different sizes in laminar premixed flames. Two models are employed for this study: a detailed PAH growth model, referred to as the kinetic Monte Carlo - aromatic site (KMC-ARS) model [Raj et al., Combust. Flame 156 (2009) 896-913]; and a multivariate PAH population balance model, referred to as the PAH - primary particle (PAH-PP) model. Both the models are solved by kinetic Monte Carlo methods. PAH mass spectra are generated using the PAH-PP model, and compared to the experimentally observed spectramore » for a laminar premixed ethylene flame. The position of the maxima of PAH dimers in the spectra and their concentrations are found to depend strongly on the collision efficiency of PAH coagulation. The variation in the collision efficiency with various flame and PAH parameters is studied to determine the factors on which it may depend. A correlation for the collision efficiency is proposed by comparing the computed and the observed spectra for an ethylene flame. With this correlation, a good agreement between the computed and the observed spectra for a number of laminar premixed ethylene flames is found. (author)« less

Energy Efficiency Improvement and Cost Saving Opportunities for the Baking Industry: An ENERGY STAR ® Guide for Plant and Energy Managers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Masanet, Eric; Therkelsen, Peter; Worrell, Ernst

The U.S. baking industry—defined in this Energy Guide as facilities engaged in the manufacture of commercial bakery products such as breads, rolls, frozen cakes, pies, pastries, and cookies and crackers—consumes over $800 million worth of purchased fuels and electricity per year. Energy efficiency improvement is an important way to reduce these costs and to increase predictable earnings, especially in times of high energy price volatility. There are a variety of opportunities available at individual plants to reduce energy consumption in a cost-effective manner. This Energy Guide discusses energy efficiency practices and energy-efficient technologies that can be implemented at the component,more » process, facility, and organizational levels. Many measure descriptions include expected savings in energy and energy-related costs, based on case study data from real-world applications in food processing facilities and related industries worldwide. Typical measure payback periods and references to further information in the technical literature are also provided, when available. A summary of basic, proven measures for improving plant-level water efficiency is also provided. The information in this Energy Guide is intended to help energy and plant managers in the U.S. baking industry reduce energy and water consumption in a cost-effective manner while maintaining the quality of products manufactured. Further research on the economics of all measures—as well as on their applicability to different production practices—is needed to assess their cost effectiveness at individual plants.« less

[Influence of cold spot temperature on 253.7 nm resonance spectra line of electrodeless discharge lamps].

PubMed

Dong, Jin-yang; Zhang, Gui-xin; Wang, Chang-quan

2012-01-01

As a kind of new electric light source, electrodeless discharge lamps are of long life, low mercury and non-stroboscopic light. The lighting effect of electrodeless discharge lamps depends on the radiation efficiency of 253.7 nm resonance spectra line to a large extent. The influence of cold temperature on 253.7 nm resonance spectra line has been studied experimentally by atomic emission spectral analysis. It was found that the radiation efficiency of 253.7 nm resonance spectra line is distributed in a nearly normal fashion with the variation of cold spot temperature, in other words, there is an optimum cold spot temperature for an electrodeless discharge lamp. At last, the results of experiments were analyzed through gas discharge theory, which offers guidance to the improvement of lighting effect for electrodeless discharge lamps.

A Two-Color Fourier Transform Mm-Wave Spectrometer for Gas Analysis Operating from 260-295 GHZ

NASA Astrophysics Data System (ADS)

Steber, Amanda L.; Harris, Brent J.; Lehmann, Kevin K.; Pate, Brooks H.

2013-06-01

We have designed a two-color mm-wave spectrometer for Fourier transform mm-wave spectroscopy that uses consumer level components for the tunable synthesizers, digital control of the pulse modulators, and digitization of the coherent free induction decay (FID). The excitation pulses are generated using an x24 active multiplier chain (AMC) that produces a peak power of 30 mW. The microwave input to the AMC is generated in a frequency up conversion circuit that accepts a microwave input frequency from about 2-4 GHz. This circuit also generates the input to the mm-wave subhamonic mixer that creates the local oscillator from a separate 2-4 GHz microwave input. Excitation pulses at two independently tunable frequencies are generated using a dual-channel source based on a low-cost, wideband synthesizer integrated circuit (Valon Technology Model 5008). The outputs of the synthesizer are pulse modulated using a PIN diode switch that is driven using the arbitrary waveform generator (AWG) output of a USB-controlled high-speed digitizer / arbitrary waveform generator combination unit (Tie Pie HS-5 530 XM). The two pulses are combined using a Wilkinson power divider before input to the up conversion circuit. The FID frequency is down converted in a two-stage mixing process to 65 MHz. The two LO frequencies used in the receiver are provided by a second Valon 5008. The FID is digitized at 200 MSamples/s using the 12-bit Tie Pie digitizer. The digital oscilloscope (and its AWG channel) and the two synthesizers use a 10 MHz reference signal from a Rubidium clock to permit time-domain signal averaging. A key feature of the digital oscilloscope is its deep memory of 32 Mpts (complemented by the 64 Mpt memory in the 240 MS/s AWG). This makes it possible to perform several one- and two-color coherent measurements, including pulse echoes and double-resonance spectroscopy, in a single "readout" experiment to speed the analysis of mm-wave rotational spectra. The spectrometer sensitivity and frequency accuracy are illustrated by high-speed measurements of OCS rotational transitions for low-abundance isotopes. Examples of pulse echo measurements to determine the collisional relaxation rate and two-color double-resonance measurements to confirm the presence of a molecular species will be illustrated using OCS as the room-temperature gas sample.

49 CFR 40.391 - What is the scope of a PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... reason to know of, approved, or acquiesced in such conduct. The individual's acceptance of benefits... necessarily applies to all its operations. Example 5 to § 40.391. Service Agent X, by exercising reasonably...

Dietary Guidelines for Adults Starting on Hemodialysis

MedlinePlus

... fish are rich in heart-healthy “omega-3” fats. Tuna and salmon (rinsed or canned without salt) and shellfish are excellent heart healthy protein choices. Snack/Dessert Milk, 4 ounces Slice of apple pie This meal ...

Group Cohesiveness, Deviation, Stress, and Conformity

DTIC Science & Technology

1993-08-11

Cola number of cups, __ Chocolate, cocoa, wine, beer/alcohol, decaffeinated coffee. Breads containing raisins, prunes, orange peel , banana , or...pudding, mince pie. Banana , avocado, pineapple, canned figs, raisins, plums and prunes. Oranges, orange juice, fru~ cocktail with pineapple. Tomato

Assessment of changes in DWI enforcement/level

DOT National Transportation Integrated Search

1991-01-01

The report summarizes a study of the long term experience of six law enforcement agencies with enforcement programs coupled with public information and education (PI&E) designed to deter driving while intoxicated (DWI). Six communities were identifie...

The consistency of disjunctive assertions.

PubMed

Johnson-Laird, P N; Lotstein, Max; Byrne, Ruth M J

2012-07-01

In two experiments, we established a new phenomenon in reasoning from disjunctions of the grammatical form either A or else B, where A and B are clauses. When individuals have to assess whether pairs of assertions can be true at the same time, they tend to focus on the truth of each clause of an exclusive disjunction (and ignore the concurrent falsity of the other clause). Hence, they succumb to illusions of consistency and of inconsistency with pairs consisting of a disjunction and a conjunction (Experiment 1), and with simpler problems consisting of pairs of disjunctions, such as eIther there is a pie or else there is a cake and Either there isn't a pie or else there is a cake (Experiment 2), that appear to be consistent with one another, but in fact are not. These results corroborate the theory that reasoning depends on envisaging models of possibilities.

DNA polymorphism at the BoLA-DRB3 gene of cattle in relation to resistance and susceptibility to leukemia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sulimova, G.E.; Udina, I.G.; Shaikhaev, G.O.

1995-09-01

Polymorphism of exon 2 of the BoLA-DRB3 gene was investigated by the PCR-RFLP method in a sample of healthy and leukemia-afflicted Black Pied cattle. Allele variety was studied and allele frequencies were determined in a total sample and in the two groups. Alleles mediating resistance (BoLA-DRB3.2{sup *}11, {sup *}23, and {sup *}28) and susceptibility to leukemia (DRB3.2{sup *}22, {sup *}24, {sup *}16, and {sup *}8) were revealed in Black Pied cattle. The dominant type of inheritance of the disease resistance was confirmed. On the basis of original and published data obtained earlier for Holstein-Friesian cattle, a conclusion was made aboutmore » the universal character of the spectrum of BoLA-DRB3 alleles providing resistance and susceptibility to leukemia. 18 refs., 1 fig., 3 tabs.« less

From ideals to deals-The effect of impartiality experience on stakeholder behavior.

PubMed

Halko, Marja-Liisa; Miettinen, Topi

2017-01-01

In this paper, we study a two-party pie-sharing problem in the presence of asymmetries in the stakeholders' private endowments. Both the two stakeholders and third-party arbitrators may influence the outcome. We consider Nash-demand negotiations, where the two stakeholders place demands and share the pie accordingly if demands are compatible, and elicit dictatorial allocations from the stakeholders and the arbitrators. The Nash demands by stakeholders are strategic; the dictatorial allocations by stakeholders and arbitrators are non-strategic. We are interested in the influence of the past arbitrator experience on stakeholder allocations and demands and the past stakeholder experience on third-party arbitration allocations. We find that the ex-arbitrators' stakeholder allocations differ more from the impartial ideal than the stakeholder allocations by those without arbitration experience. In contrast with previous findings, the arbitration outcomes do not depend on the asymmetries in the previous stakeholder roles.

From ideals to deals—The effect of impartiality experience on stakeholder behavior

PubMed Central

2017-01-01

In this paper, we study a two-party pie-sharing problem in the presence of asymmetries in the stakeholders' private endowments. Both the two stakeholders and third-party arbitrators may influence the outcome. We consider Nash-demand negotiations, where the two stakeholders place demands and share the pie accordingly if demands are compatible, and elicit dictatorial allocations from the stakeholders and the arbitrators. The Nash demands by stakeholders are strategic; the dictatorial allocations by stakeholders and arbitrators are non-strategic. We are interested in the influence of the past arbitrator experience on stakeholder allocations and demands and the past stakeholder experience on third-party arbitration allocations. We find that the ex-arbitrators' stakeholder allocations differ more from the impartial ideal than the stakeholder allocations by those without arbitration experience. In contrast with previous findings, the arbitration outcomes do not depend on the asymmetries in the previous stakeholder roles. PMID:28786988

Spatial and temporal controls target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos.

PubMed

Hunter, C P; Kenyon, C

1996-10-18

The early asymmetric cleavages of Caenorhabditis elegans embryos produce blastomeres with distinct developmental potentials. Here, we show that the caudal-like homeodomain protein PAL-1 is required to specify the somatic identity of one posterior blastomere in the 4 cell embryo. We find that pal-1 activity is sequentially restricted to this blastomere. First, at the 4 cell stage, it is translated only in the two posterior blastomeres. Then, its function is restricted to one of these blastomeres. This second targeting step is dependent on the activities of the posteriorly localized SKN-1 and asymmetrically segregated PIE-1 proteins. We propose that the segregation of PIE-1, combined with the temporal decay of SKN-1, targets pal-1 activity to this posterior lineage, thus coupling the regulation of this conserved posterior patterning gene to asymmetric cell cleavages.

Tinker, Thinker, Maker and CEO: Reimagining the Physics Student as Engineer, Inventor, and Entrepreneur

NASA Astrophysics Data System (ADS)

Bailey, Crystal

2015-03-01

We live in an era of immense opportunity for physics graduates: their scientific training helps to make them key members of industry teams developing new technologies, or translating cutting-edge research into viable products. Physics as a discipline stands to make tremendous gains by implementing new educational approaches which provide training for success in what is increasingly the largest employment base for physicists: the private sector. In this talk, I will examine the role of physicist as innovator and how this role intersects with other similar STEM disciplines (such as engineering), and provide some insight into how implementing physics innovation and entrepreneurship (PIE) education will benefit both physics departments and the students they serve, regardless of students' eventual career choices. I will also talk about some exciting new PIE related developments in the physics community, and provide information about how educators can get involved in this growing movement.

Fracto-emission from single fibres of Kevlar

NASA Technical Reports Server (NTRS)

Dickinson, J. T.; Jahan-Latibari, A.; Jensen, L. C.

1985-01-01

Fracto-emission (FE) is the emission of particles (e.g. electrons, ions and photons) during and following fracture. In this paper, we present data on electron emission (EE) and positive ion emission (PIE) from the tensile fracture of Kevlar single fibers. The fibers were initially fractured in pure tension, where a stranded form of fracture was observed, often with multiple peaks spread over several hundred microseconds. The loading condition was then changed by stretching and breaking the fibers over a dull metal edge. With this change in the loading, different forms of fracture were observed, each with distinctive forms of emission curves. When fracture was accompanied by extensive fibril formation, total emission was high and both EE and PIE decay times were long relative to fractures in which little fibril formation occurred. The results of this study suggest that FE has some applicability as a tool for the detection of fracture mechanisms of single fibers.

An Approach for Peptide Identification by De Novo Sequencing of Mixture Spectra.

PubMed

Liu, Yi; Ma, Bin; Zhang, Kaizhong; Lajoie, Gilles

2017-01-01

Mixture spectra occur quite frequently in a typical wet-lab mass spectrometry experiment, which result from the concurrent fragmentation of multiple precursors. The ability to efficiently and confidently identify mixture spectra is essential to alleviate the existent bottleneck of low mass spectra identification rate. However, most of the traditional computational methods are not suitable for interpreting mixture spectra, because they still take the assumption that the acquired spectra come from the fragmentation of a single precursor. In this manuscript, we formulate the mixture spectra de novo sequencing problem mathematically, and propose a dynamic programming algorithm for the problem. Additionally, we use both simulated and real mixture spectra data sets to verify the merits of the proposed algorithm.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ammigan, K.; Hurh, P.

The Radiation Damage In Accelerator Target Environments (RaDIATE) collaboration was founded in 2012 and currently consists of over 50 participants and 11 institutions globally. Due to the increasing power of future proton accelerator sources in target facilities, there is a critical need to further understand the physical and thermo-mechanical radiation response of target facility materials. Thus, the primary objective of the RaDIATE collaboration is to draw on existing expertise in the nuclear materials and accelerator targets fields to generate new and useful materials data for application within the accelerator and fission/fusion communities. Current research activities of the collaboration include postmore » irradiation examination (PIE) of decommissioned components from existing beamlines such as the NuMI beryllium beam window and graphite NT-02 target material. PIE of these components includes advanced microstructural analyses (SEM/TEM, EBSD, EDS) and micro-mechanics technique such as nano-indentation, to help characterize any microstructural radiation damage incurred during operation. New irradiation campaigns of various candidate materials at both low and high energy beam facilities are also being pursued. Beryllium helium implantation studies at the University of Surrey as well as high energy proton irradiation of various materials at Brookhaven National Laboratory’s BLIP facility have been initiated. The program also extends to beam-induced thermal shock experiments using high intensity beam pulses at CERN’s HiRadMat facility, followed by advanced PIE activities to evaluate thermal shock resistance of the materials. Preliminary results from ongoing research activities, as well as the future plans of the RaDIATE collaboration R&D program will be discussed.« less

Breeding ecology and nesting habitat associations of five marsh bird species in western New York

USGS Publications Warehouse

Lor, S.; Malecki, R.A.

2006-01-01

Nesting habitats and nest success of five species of marsh birds were studied during 1997 and 1998 at the Iroquois National Wildlife Refuge (NWR) and the adjacent Oak Orchard and Tonawanda State Wildlife Management Areas (WMA) located in western New York. Nest searches located 18 American Bittern (Botaurus lentiginosus), 117 Least Bittern (Ixobrychus exilis), 189 Pied-billed Grebe (Podilymbus podiceps), 23 Sora (Porzana carolina), and 72 Virginia Rail (Rallus limicola) nests. Average nest densities in 1998, our best nest searching year, ranged from 0.01/ha for Soras (N = 8) to 0.28/ha for Pied-billed Grebes (N = 160). Mayfield nest success estimates for Least Bittern were 80% (N = 16) in 1997 and 46% (N = 37) in 1998. Nest success estimates were 72% (N = 55) for Pied-billed Grebe, 43% (N = 6) for Sora, and 38% (N = 20) for Virginia Rail. Nests of all five species were located in ???70% emergent vegetation with a mean water depth of 24-56 cm and an average vegetation height that ranged from 69-133 cm. Logistic regression models were developed for each species using habitat variables at nest and random site locations. Each model was ranked with Akaike's Information Criterion for small sample size (AICc). In general, our best models indicated that increased emergent vegetation and horizontal cover with shallow water depths improved the odds of encountering marsh bird nests in the wetlands of western New York. We suggest that managing wetlands as a complex, at different stages of succession, would best benefit marsh bird species.

Exopolysaccharides from Lactobacillus delbrueckii OLL1073R-1 modulate innate antiviral immune response in porcine intestinal epithelial cells.

PubMed

Kanmani, Paulraj; Albarracin, Leonardo; Kobayashi, Hisakazu; Iida, Hikaru; Komatsu, Ryoya; Humayun Kober, A K M; Ikeda-Ohtsubo, Wakako; Suda, Yoshihito; Aso, Hisashi; Makino, Seiya; Kano, Hiroshi; Saito, Tadao; Villena, Julio; Kitazawa, Haruki

2018-01-01

Previous studies demonstrated that the extracellular polysaccharides (EPSs) produced by Lactobacillus delbrueckii OLL1073R-1 (LDR-1) improve antiviral immunity, especially in the systemic and respiratory compartments. However, it was not studied before whether those EPSs are able to beneficially modulate intestinal antiviral immunity. In addition, LDR-1-host interaction has been evaluated mainly with immune cells while its interaction with intestinal epithelial cells (IECs) was not addressed before. In this work, we investigated the capacity of EPSs from LDR-1 to modulate the response of porcine IECs (PIE cells) to the stimulation with the Toll-like receptor (TLR)-3 agonist poly(I:C) and the role of TLR2, TLR4, and TLR negative regulators in the immunoregulatory effect. We showed that innate immune response triggered by TLR3 activation in porcine IECs was differentially modulated by EPS from LDR-1. EPSs treatment induced an increment in the expression of interferon (IFN)-α and IFN-β in PIE cells after the stimulation with poly(I:C) as well as the expression of the antiviral factors MxA and RNase L. Those effects were related to the reduced expression of A20 in EPS-treated PIE cells. EPS from LDR-1 was also able to reduce the expression of IL-6 and proinflammatory chemokines. Although further in vivo studies are needed, our results suggest that these EPSs or a yogurt fermented with LDR-1 have potential to improve intestinal innate antiviral response and protect against intestinal viruses. Copyright © 2017 Elsevier Ltd. All rights reserved.

Algorithmic pie-crusting of the medial collateral ligament guided by sensing technology affects the use of constrained inserts during total knee arthroplasty.

PubMed

Amundsen, Spencer; Lee, Yuo-Yu; González Della Valle, Alejandro

2017-06-01

Intra-operative sensing technology is an alternative to standard techniques in total knee arthroplasty (TKA) for determining balance by providing quantitative analysis of loads and point of contact throughout a range of motion. We used intra-operative sensing (VERASENSE-OrthoSensor, Inc.) to examine pie-crusting release of the medial collateral ligament in knees with varus deformity (study group) in comparison to a control group where balance was obtained using a classic release technique and assessed using laminar spreaders, spacer blocks, manual stress, and a ruler. The surgery was performed by a single surgeon utilizing measured resection and posterior-stabilized, cemented implants. Seventy-five study TKAs were matched 1:3 with 225 control TKAs. Outcome variables included the use of a constrained insert, functional- and knee-specific Knee Society score (KSS) at six weeks, four months, and one year post-operatively. Outcomes were analyzed in a multivariate model controlling for age, sex, BMI, and severity of deformity. The use of a constrained insert was significantly lower in the study group (5.3 vs. 13.8%; p = 0.049). The use of increased constraint was not significant between groups with increasing deformity. There was no difference in functional KSS and knee-specific KSS between groups at any follow-up interval. An algorithmic pie-crusting technique guided by intra-operative sensing is associated with decreased use of constrained inserts in TKA patients with a pre-operative varus deformity. This may cause a positive shift in value and cost savings.

SpecOMS: A Full Open Modification Search Method Performing All-to-All Spectra Comparisons within Minutes.

PubMed

David, Matthieu; Fertin, Guillaume; Rogniaux, Hélène; Tessier, Dominique

2017-08-04

The analysis of discovery proteomics experiments relies on algorithms that identify peptides from their tandem mass spectra. The almost exhaustive interpretation of these spectra remains an unresolved issue. At present, an important number of missing interpretations is probably due to peptides displaying post-translational modifications and variants that yield spectra that are particularly difficult to interpret. However, the emergence of a new generation of mass spectrometers that provide high fragment ion accuracy has paved the way for more efficient algorithms. We present a new software, SpecOMS, that can handle the computational complexity of pairwise comparisons of spectra in the context of large volumes. SpecOMS can compare a whole set of experimental spectra generated by a discovery proteomics experiment to a whole set of theoretical spectra deduced from a protein database in a few minutes on a standard workstation. SpecOMS can ingeniously exploit those capabilities to improve the peptide identification process, allowing strong competition between all possible peptides for spectrum interpretation. Remarkably, this software resolves the drawbacks (i.e., efficiency problems and decreased sensitivity) that usually accompany open modification searches. We highlight this promising approach using results obtained from the analysis of a public human data set downloaded from the PRIDE (PRoteomics IDEntification) database.

A data reduction package for multiple object spectroscopy

NASA Technical Reports Server (NTRS)

Hill, J. M.; Eisenhamer, J. D.; Silva, D. R.

1986-01-01

Experience with fiber-optic spectrometers has demonstrated improvements in observing efficiency for clusters of 30 or more objects that must in turn be matched by data reduction capability increases. The Medusa Automatic Reduction System reduces data generated by multiobject spectrometers in the form of two-dimensional images containing 44 to 66 individual spectra, using both software and hardware improvements to efficiently extract the one-dimensional spectra. Attention is given to the ridge-finding algorithm for automatic location of the spectra in the CCD frame. A simultaneous extraction of calibration frames allows an automatic wavelength calibration routine to determine dispersion curves, and both line measurements and cross-correlation techniques are used to determine galaxy redshifts.

49 CFR 40.383 - What procedures apply if you contest the issuance of a PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.383... you. (d) In cases where there are material factual issues in dispute, the Director or his or her...

49 CFR 40.379 - How do you contest the issuance of a PIE?

Code of Federal Regulations, 2010 CFR

2010-10-01

... WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.379 How do you contest the... based on the record provided by the initiating official (i.e., the NOPE and any supporting information...

9 CFR 381.158 - Poultry dinners (frozen) and pies.

Code of Federal Regulations, 2012 CFR

2012-01-01

... including bone and breading may be used in lieu of minimum 18 percent or 2 ounces of cooked deboned poultry meat and the cooked poultry including bone and breading shall not contain more than 30 percent breading. ...

9 CFR 381.158 - Poultry dinners (frozen) and pies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... including bone and breading may be used in lieu of minimum 18 percent or 2 ounces of cooked deboned poultry meat and the cooked poultry including bone and breading shall not contain more than 30 percent breading. ...

9 CFR 381.158 - Poultry dinners (frozen) and pies.

Code of Federal Regulations, 2014 CFR

2014-01-01

... including bone and breading may be used in lieu of minimum 18 percent or 2 ounces of cooked deboned poultry meat and the cooked poultry including bone and breading shall not contain more than 30 percent breading. ...

9 CFR 381.158 - Poultry dinners (frozen) and pies.

Code of Federal Regulations, 2013 CFR

2013-01-01

... including bone and breading may be used in lieu of minimum 18 percent or 2 ounces of cooked deboned poultry meat and the cooked poultry including bone and breading shall not contain more than 30 percent breading. ...

9 CFR 381.158 - Poultry dinners (frozen) and pies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... including bone and breading may be used in lieu of minimum 18 percent or 2 ounces of cooked deboned poultry meat and the cooked poultry including bone and breading shall not contain more than 30 percent breading. ...

Thanksgiving Project

ERIC Educational Resources Information Center

Hilden, Pauline

1976-01-01

A teacher describes a Thanksgiving project in which 40 educable mentally retarded students (6-13 years old) made and served their own dinner of stew, butter, bread, ice cream, and pie, and in the process learned about social studies, cooking, and proper meal behavior. (CL)

The Humble Pie--Half-Baked or Well Done?

ERIC Educational Resources Information Center

Hunt, Neville; Mashhoudy, Houshang

2008-01-01

This article re-examines the much maligned piechart and provides justification for its use. It identifies common pitfalls when drawing piecharts in Microsoft Excel and offers advice on how to avoid them. (Contains 6 figures and 5 tables.)

DASH diet to lower high blood pressure

MedlinePlus

... breakfast. For dessert, choose fresh fruit or low-fat frozen yogurt instead of high-calorie sweets, such as cakes or pies. Choose healthy snacks, such as unsalted rice cakes or popcorn, raw vegetables, or yogurt. Dried fruits, seeds, and nuts ...

49 CFR 40.365 - What is the Department's policy concerning starting a PIE proceeding?

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.365... constitutes a conflict of interest under this part (e.g., a laboratory that derives a financial benefit from...

Centripetal Force on an Overhead Projector.

ERIC Educational Resources Information Center

Rheam, Harry

1995-01-01

Describes two simple demonstrations of an object moving in a straight line tangent to the circle if centripetal force is removed. Demonstrations use a pie plate and petri dish with ball bearings to illustrate the phenomena on an overhead projector. (LZ)

Seismic retrofit of spliced sleeve connections for precast bridge piers.

DOT National Transportation Integrated Search

2017-03-01

Grouted Splice Sleeve (GSS) connectors are being considered for connecting bridge columns, footings, and pier caps in Accelerated Bridge Construction (ABC). A repair technique for precast reinforced concrete bridge column-to-footing and column-to-pie...

Experimental field test of proposed pedestrian safety messages. Volume 3

DOT National Transportation Integrated Search

1983-11-01

Author's abstract: A detailed re-analysis of available pedestrian accident data was utilized to define three sets of pedestrian safety public information and education (PI&E) Messages. These messages were then produced and field tested. The objective...

A Howling Success: How To Put Your "Pied Dedans."

ERIC Educational Resources Information Center

Smillie, Barrie

1996-01-01

Discusses humorous incidences of translating an idiom from one language literally into another. Notes that words with a similar look or sound in English and the target language, or within the target language, cause confusion. (Author/CK)

[Application of pie-crusting the medial collateral ligament release in arthroscopic surgery for posterior horn of 
medial meniscus in knee joint].

PubMed

Zhu, Weihong; Tang, Qi; Liao, Lele; Li, Ding; Yang, Yang; Chen, You

2017-09-28

To explore the effectiveness and safety of pie-crusting the medial collateral ligament release (MCL) in treating posterior horn of medial meniscus (PHMM) tear in tight medial tibiofemoral compartment of knee joint.
 Methods: Thirty-two consecutive patients with PHMM tear in tight medial tibiofemoral compartment of knee joint were admitted to our department from January, 2013 to December, 2014. All patients were performed pie-crusting the MCL release at its tibial insertion with 18-gauge intravenous needle. All patients were evaluated by valgus stress test and bilateral valgus stress radiograph at postoperative 1st day, 4th week and 12th week. Visual Analogue Scales (VAS), Lysholm scores, Tegner scores and International Knee Documentation Committee (IKDC) scores were recorded at the 1st, 3th, 6th month follow-up, then follow-up every 6 months.
 Results: The mean follow-up was 28 (24-36) months. All cases were negative in valgus stress test. MCL rupture, femoral fracture, articular cartilage lesion and neurovascular injury were not found at the last follow-up. The median medial joint space width of affected side and unaffected side for valgus stress radiographs were 6.8 mm and 4.3 mm (P<0.05) at the 1st day, 5.5 mm and 4.2 mm 
(P<0.05) in the 4th week and 4.8 mm and 4.3 mm (P>0.05) at the 12th week, respectively. VAS scores was changed from 4.5±1.5 preoperatively to 1.7±1.0 at the final follow-up (t=16.561, P<0.05). Lysholm scores was changed from 52.3±5.8 preoperatively to 93.2±6.3 at the final follow-up (t=-41.353, P<0.05). Tegner scores was changed from 4.1±1.1 preoperatively to 5.5±0.6 at the final follow-up (t=-18.792, P<0.05). IKDC scores was changed from 54.5±6.2 preoperative to 93.8±4.5 at the final follow-up (t=-38.253, P<0.05).
 Conclusion: Pie-crusting the medial collateral ligament release is a safe, minimal invasive and effective surgical option for posterior horn of medial meniscus tear in tight medial tibiofemoral compartment of knee joint.

An investigation of a mathematical model for atmospheric absorption spectra

NASA Technical Reports Server (NTRS)

Niple, E. R.

1979-01-01

A computer program that calculates absorption spectra for slant paths through the atmosphere is described. The program uses an efficient convolution technique (Romberg integration) to simulate instrument resolution effects. A brief information analysis is performed on a set of calculated spectra to illustrate how such techniques may be used to explore the quality of the information in a spectrum.

Musical sound analysis/synthesis using vector-quantized time-varying spectra

NASA Astrophysics Data System (ADS)

Ehmann, Andreas F.; Beauchamp, James W.

2002-11-01

A fundamental goal of computer music sound synthesis is accurate, yet efficient resynthesis of musical sounds, with the possibility of extending the synthesis into new territories using control of perceptually intuitive parameters. A data clustering technique known as vector quantization (VQ) is used to extract a globally optimum set of representative spectra from phase vocoder analyses of instrument tones. This set of spectra, called a Codebook, is used for sinusoidal additive synthesis or, more efficiently, for wavetable synthesis. Instantaneous spectra are synthesized by first determining the Codebook indices corresponding to the best least-squares matches to the original time-varying spectrum. Spectral index versus time functions are then smoothed, and interpolation is employed to provide smooth transitions between Codebook spectra. Furthermore, spectral frames are pre-flattened and their slope, or tilt, extracted before clustering is applied. This allows spectral tilt, closely related to the perceptual parameter ''brightness,'' to be independently controlled during synthesis. The result is a highly compressed format consisting of the Codebook spectra and time-varying tilt, amplitude, and Codebook index parameters. This technique has been applied to a variety of harmonic musical instrument sounds with the resulting resynthesized tones providing good matches to the originals.

New Mexico Fiber-Optic Link Marks Giant Leap Toward Future of Radio Astronomy

NASA Astrophysics Data System (ADS)

1998-12-01

SOCORRO, NM -- Scientists and engineers at the National Radio Astronomy Observatory (NRAO) have made a giant leap toward the future of radio astronomy by successfully utilizing the Very Large Array (VLA) radio telescope in conjunction with an antenna of the continent-wide Very Long Baseline Array (VLBA) using the longest fiber-optic data link ever demonstrated in radio astronomy. The 65-mile fiber link will allow scientists to use the two National Science Foundation (NSF) facilities together in real time, and is the first step toward expanding the VLA to include eight proposed new radio-telescope antennas throughout New Mexico. LEFT: Miller Goss, NRAO's director of VLA/VLBA Operations, unveils graphic showing success of the Pie Town-VLA fiber link. The project, funded by the NSF and Associated Universities, Inc. (AUI), which operates NRAO for the NSF, links the VLA and the VLBA antenna in Pie Town, NM, using a Western New Mexico Telephone Co. fiber-optic cable. The successful hookup was announced at a ceremony that also marked the 10th anniversary of NRAO's Operations Center in Socorro. "Linking the Pie Town antenna to the VLA quadruples the VLA's ability to make detailed images of astronomical objects," said Paul Vanden Bout, NRAO's Director. "This alone makes the link an advance for science, but its greater importance is that it clearly demonstrates the technology for improving the VLA's capabilities even more in the future." "Clearly, the big skies and wide open spaces in New Mexico create near perfect conditions for the incredible astronomical assets located in our state. This new fiber-optic link paves the way for multiplying the already breathtaking scientific capabilities of the VLA," Senator Pete Domenici (R-NM) said. The VLA is a system of 27 radio-telescope antennas distributed over the high desert west of Socorro, NM, in the shape of a giant "Y." Made famous in movies, commercials and numerous published photos, the VLA has been one of the most productive and versatile astronomical observatories in the world since its dedication in 1980. The VLBA is a continent-wide system of 10 radio telescopes distributed across the continental United States, Hawaii and St. Croix in the Caribbean. In both the VLA and VLBA, the cosmic radio waves received by each antenna are combined with those received from every other antenna in the system to produce images with extremely great resolving power, or ability to see fine detail. The more widely separated the antennas, the greater the resolving power. The greatest separation between antennas of the VLA is 20 miles; in the VLBA, 5,000 miles. If your eyes could see the same level of detail as the VLA, you could, at the distance from New York to Los Angeles, make out an object the size of a small car. With the resolving power of the VLBA, you could read the owner's manual. The VLBA can make images hundreds of times more detailed than those available from the Hubble Space Telescope. However, because of the way in which such multi-antenna radio telescopes, called interferometers, work, there is a gap between the levels of detail obtainable with the VLA and the VLBA. Linking the VLA to the VLBA Pie Town antenna is the first step toward filling in that gap and allowing astronomers to see all scales of structure -- small, medium-sized, and large -- in objects such as stars, galaxies and quasars. Additional antennas, distributed throughout New Mexico, would fully fill that gap. Adding the new antennas to the VLA "would provide the capability to image astronomical objects on all spatial scales, from the very largest to the very smallest. The combination of the VLA and VLBA then would be the only single instrument in astronomy covering such a range of spatial scales, and thus a tool of great and unique value to science," said Vanden Bout. LEFT: NRAO Director Paul Vanden Bout, left, speaks with U.S. Senator Pete Domenici, right, following the ceremony at the Array Operations Center in Socorro Dec. 15. Nobel Laureate Robert Wilson is in the background. The added antennas are part of a comprehensive plan that the NRAO has developed for upgrading the VLA. The existing array of antennas was authorized by Congress in 1972 and built from 1974 to 1980. The upgrade plan also includes replacing the original electronic and digital equipment from the 1970s with modern technology. Such refurbishment will improve the VLA's scientific capabilities from tenfold to a hundredfold in all research areas, and for a modest investment would provide an enhanced facility many times more powerful than the original VLA. "Though the VLA today is hundreds of times more capable than its original design, some of the technologies of the 1970s that still are in use threaten the instrument with premature obsolescence," said Miller Goss, NRAO's director of VLA/VLBA operations. "Replacing those with today's technology will assure the VLA's continued role as one of the world's premier astronomical research facilities. The success of the Pie Town-VLA link shows one way this can happen." "We are enthusiastic and excited about this development, not only because of the scientific value of the Pie Town link itself, but more importantly because it proves the concept of expanding the VLA," said Robert Dickman, of the NSF's Division of Astronomical Sciences. "The AUI Board of Trustees, in providing 30 percent of the support for the optical fiber link from its corporate reserves, recognizes the scientific importance of making this connection between the VLA and the VLBA," said Martha P. Haynes, AUI's Interim President. Referring to the scientific phenomenon of forming images using the arrays to produce "interferometric fringes," Haynes, a radio astronomer herself, remarked that "We view the provision of corporate matching funds for this project as a 'fringe benefit' for NRAO." Work on the Pie Town-VLA link began in late 1997. Project engineer Ron Beresford, who came from the Australia Telescope National Facility to work on the link, said "This is the longest fiber-optic link yet demonstrated in radio astronomy. Radio telescopes in Australia and elsewhere are connected by a few miles of fiber, but the link between Pie Town and the VLA is more than 20 times longer than any other such fiber link." The project involved designing, building and testing specialized electronic equipment to connect both the VLA and the Pie Town antenna to the fiber-optic cable. In addition, both hardware and software at the VLA had to be modified to allow using the Pie Town antenna as an integral part of the VLA. "This was an extremely complex undertaking, and it succeeded because of an outstanding team effort involving scientists, engineers and technicians," Goss said. The VLA and VLBA are facilities of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

Raman Spectroscopy of DNA Packaging in Individual Human Sperm Cells distinguishes Normal from Abnormal Cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huser, T; Orme, C; Hollars, C

Healthy human males produce sperm cells of which about 25-40% have abnormal head shapes. Increases in the percentage of sperm exhibiting aberrant sperm head morphologies have been correlated with male infertility, and biochemical studies of pooled sperm have suggested that sperm with abnormal shape may contain DNA that has not been properly repackaged by protamine during spermatid development. We have used micro-Raman spectroscopy to obtain Raman spectra from individual human sperm cells and examined how differences in the Raman spectra of sperm chromatin correlate with cell shape. We show that Raman spectra of individual sperm cells contain vibrational marker modesmore » that can be used to assess the efficiency of DNA-packaging for each cell. Raman spectra obtained from sperm cells with normal shape provide evidence that DNA in these sperm is very efficiently packaged. We find, however, that the relative protein content per cell and DNA packaging efficiencies are distributed over a relatively wide range for sperm cells with both normal and abnormal shape. These findings indicate that single cell Raman spectroscopy should be a valuable tool in assessing the quality of sperm cells for in-vitro fertilization.« less

A New Strategy for Latin America

DTIC Science & Technology

1992-04-01

resulted in six significant racial groups; Indians, Europeans, Mestizo (Indians & Europeans); Black, Mulattoes (Black & Europeans), and Zambos (Indians...slice of the budget pie , a priority ranking of these countries would establish where the best benefits lie for US national security. As discussed, Latin

Experimental field test of proposed pedestrian safety messages. Volume 2, Child messages

DOT National Transportation Integrated Search

1983-11-01

Author's abstract: A detailed re-analysis of available pedestrian accident data was utilized to define three sets of pedestrian safety public information and education (PI&E) messages. These messages were then produced and field tested. The objective...

Segmentation: Slicing the Urban Pie.

ERIC Educational Resources Information Center

Keim, William A.

1981-01-01

Explains market segmentation and defines undifferentiated, concentrated, and differentiated marketing strategies. Describes in detail the marketing planning process at the Metropolitan Community Colleges. Focuses on the development and implementation of an ongoing recruitment program designed for the market segment composed of business employees.…

Combining enforcement and public information to deter DWI : the experience of three communities

DOT National Transportation Integrated Search

1990-04-01

This report summarizes the results of three field tests of the concept of combining enforcement with public information and education (PI&E) activities to achieve general deterrence of driving while intoxicated (DWI). Test communities were Clearwater...

Enforcement and public information strategies for DWI deterrence : the Indianapolis, Indiana experience

DOT National Transportation Integrated Search

1988-07-01

This report summarizes the results of a field test of attempting to achieve driving while intoxicated (DWI) general deterrence by combining enforcement efforts with public information and education (PI&E) activities designed to heighten public awaren...

49 CFR 40.371 - On what information does an initiating official rely in deciding whether to start a PIE proceeding?

Code of Federal Regulations, 2012 CFR

2012-10-01

... Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public... affect the initiating official's determination about whether it is necessary to send a correction notice...

49 CFR 40.371 - On what information does an initiating official rely in deciding whether to start a PIE proceeding?

Code of Federal Regulations, 2011 CFR

2011-10-01

... Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public... affect the initiating official's determination about whether it is necessary to send a correction notice...

49 CFR 40.371 - On what information does an initiating official rely in deciding whether to start a PIE proceeding?

Code of Federal Regulations, 2014 CFR

2014-10-01

... Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public... affect the initiating official's determination about whether it is necessary to send a correction notice...

49 CFR 40.371 - On what information does an initiating official rely in deciding whether to start a PIE proceeding?

Code of Federal Regulations, 2013 CFR

2013-10-01

... Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public... affect the initiating official's determination about whether it is necessary to send a correction notice...

49 CFR 40.371 - On what information does an initiating official rely in deciding whether to start a PIE proceeding?

Code of Federal Regulations, 2010 CFR

2010-10-01

... Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public... affect the initiating official's determination about whether it is necessary to send a correction notice...

The Automatic Recognition of the Abnormal Sky-subtraction Spectra Based on Hadoop

NASA Astrophysics Data System (ADS)

An, An; Pan, Jingchang

2017-10-01

The skylines, superimposing on the target spectrum as a main noise, If the spectrum still contains a large number of high strength skylight residuals after sky-subtraction processing, it will not be conducive to the follow-up analysis of the target spectrum. At the same time, the LAMOST can observe a quantity of spectroscopic data in every night. We need an efficient platform to proceed the recognition of the larger numbers of abnormal sky-subtraction spectra quickly. Hadoop, as a distributed parallel data computing platform, can deal with large amounts of data effectively. In this paper, we conduct the continuum normalization firstly and then a simple and effective method will be presented to automatic recognize the abnormal sky-subtraction spectra based on Hadoop platform. Obtain through the experiment, the Hadoop platform can implement the recognition with more speed and efficiency, and the simple method can recognize the abnormal sky-subtraction spectra and find the abnormal skyline positions of different residual strength effectively, can be applied to the automatic detection of abnormal sky-subtraction of large number of spectra.

Spectra Optia granulocyte apheresis collections result in higher collection efficiency of viable, functional neutrophils in a randomized, crossover, multicenter trial.

PubMed

Cancelas, Jose A; Padmanabhan, Anand; Le, Tuan; Ambruso, Daniel R; Rugg, Neeta; Worsham, D Nicole; Pinkard, Susan L; Graminske, Sharon; Buck, Jennifer; Goldberg, Julie; Bill, Jerry

2015-04-01

Granulocyte transfusion from healthy donors is used in the treatment of patients with granulocyte function defects, or transient neutropenia and severe bacterial or fungal infections resistant to maximal antimicrobial treatment. This study evaluated the performance and safety of the newly developed granulocyte collection protocol of the Spectra Optia in a prospective, multicenter, open-label, randomized, paired crossover trial compared with the COBE Spectra apheresis system in a population of 32 evaluable healthy subjects. All subjects received granulocyte-colony-stimulating factor and dexamethasone before collection. Granulocyte procedures from Spectra Optia apheresis procedures had an approximately 23% higher polymorphonuclear (PMN) collection efficiency (CE) than the COBE Spectra collections (mean, 53.7% vs. 43.2%; p < 0.01), while the platelet CE (10.9% vs. 10.8%, respectively) and hematocrit (7.4% vs. 7.4%) were comparable between collections on both devices. Spectra Optia collections generated a higher total PMN yield per liter of blood processed than those produced by the COBE Spectra (with means of 8.6 × 10(10) vs. 6.8 × 10(10) , respectively). Granulocyte viability was more than 99% with both devices, and chemotaxic and bacterial killing activities of circulating versus collected granulocytes were similarly preserved. Fewer operator adjustments were required with Spectra Optia and there was no significant difference in the number or intensity of adverse events between instruments. CE of the granulocyte collection procedure with the Spectra Optia was approximately 10 percentage points higher than with the COBE Spectra, required less operator involvement, and is safe for clinical implementation. © 2014 AABB.

Correlation of soil and sediment organic matter polarity to aqueous sorption of nonionic compounds

USGS Publications Warehouse

Kile, D.E.; Wershaw, R. L.; Chiou, C.T.

1999-01-01

Polarities of the soiL/sediment organic matter (SOM) in 19 soil and 9 freshwater sediment sam pies were determined from solid-state 13C-CP/MAS NMR spectra and compared with published partition coefficients (K(oc)) of carbon tetrachloride (CT) from aqueous solution. Nondestructive analysis of whole samples by solid-state NMR permits a direct assessment of the polarity of SOM that is not possible by elemental analysis. The percent of organic carbon associated with polar functional groups was estimated from the combined fraction of carbohydrate and carboxylamide-ester carbons. A plot of the measured partition coefficients (K(oc)) of carbon tetrachloride (CT) vs. percent polar organic carbon (POC) shows distinctly different populations of soils and sediments as well as a roughly inverse trend among the soil/sediment populations. Plots of K(oc) values for CT against other structural group carbon fractions did not yield distinct populations. The results indicate that the polarity of SOM is a significant factor in accounting for differences in K(oc) between the organic matter in soils and sediments. The alternate direct correlation of the sum of aliphatic and aromatic structural carbons with K(oc) illustrates the influence of nonpolar hydrocarbon on solute partition interaction. Additional elemental analysis data of selected samples further substantiate the effect of the organic matter polarity on the partition efficiency of nonpolar solutes. The separation between soil and sediment samples based on percent POC reflects definite differences of the properties of soil and sediment organic matters that are attributable to diagenesis.Polarities of the soil/sediment organic matter (SOM) in 19 soil and 9 freshwater sediment samples were determined from solid-state 13C-CP/MAS NMR spectra and compared with published partition coefficients (Koc) of carbon tetrachloride (CT) from aqueous solution. Nondestructive analysis of whole samples by solid-state NMR permits a direct assessment of the polarity of SOM that is not possible by elemental analysis. The percent of organic carbon associated with polar functional groups was estimated from the combined fraction of carbohydrate and carboxyl-amide-ester carbons. A plot of the measured partition coefficients (Koc) of carbon tetrachloride (CT) vs. percent polar organic carbon (POC) shows distinctly different populations of soils and sediments as well as a roughly inverse trend among the soil/sediment populations. Plots of Koc values for CT against other structural group carbon fractions did not yield distinct populations. The results indicate that the polarity of SOM is a significant factor in accounting for differences in Koc between the organic matter in soils and sediments. The alternate direct correlation of the sum of aliphatic and aromatic structural carbons with Koc illustrates the influence of nonpolar hydrocarbon on solute partition interaction. Additional elemental analysis data of selected samples further substantiate the effect of the organic matter polarity on the partition efficiency of nonpolar solutes. The separation between soil and sediment samples based on percent POC reflects definite differences of the properties of soil and sediment organic matters that are attributable to diagenesis.

Sweetie Pie Thornless Blackberry

USDA-ARS?s Scientific Manuscript database

‘Sweetie Pie’ is a new thornless blackberry (Rubus L. subg. Watson) cultivar developed and released by the USDA-ARS Thad Cochran Southern Horticultural Laboratory. ‘Sweetie Pie’ is a vigorous, semi-erect blackberry that produces moderate yields of sweet high quality fruit having excellent flavor, ...

Enforcement and public information strategies for DWI general deterrence : the Boise City, Idaho experience

DOT National Transportation Integrated Search

1987-08-01

This report summarizes the results of a field test of attempting to achieve driving while intoxicated (DWI) general deterrence by combining enforcement efforts with public information and education (PI&E) activities designed to heighten public awaren...

Using Illustrations in the Literature and Writing Programs.

ERIC Educational Resources Information Center

Silverblank, Fran

1982-01-01

Uses illustrations from three different editions of "The Pied Piper of Hamlin" to demonstrate that readers bring their own intepretations to a piece of literature and that writers choose a variety of words, word combinations, and comparisons to describe what they perceive. (FL)

The Ups and Downs of Information Graphics.

ERIC Educational Resources Information Center

Jungblut, Joseph A.

1988-01-01

Describes the four basic information graphics: fever, bar, pie, and map. Provides five tips for creating visuals for graphs: (1) plot the numbers first; (2) set the numbers horizontally; (3) make it accurate; (4) use artwork that fits; and (5) use appropriate type. (MS)

Experimental field test of proposed pedestrian safety messages. Volume 1, Methods and materials development

DOT National Transportation Integrated Search

1983-11-01

Author's abstract: A detailed re-analysis of available pedestrian accident data was utilized to define three sets of pedestrian safety public information and education (PI&E) messages. These messages were then produced and field tested. The objective...

Potential exposure to human prescription pharmaceutical residues from wastewater

EPA Science Inventory

Pharmaceuticals in the environment (PiE) pose a complicated problem, involving multiple dissimilar compounds, multiple routes of potential exposure, and a range of potentially affected organisms that span the tree of life. Key uncertainties include not knowing which of the thous...

Food Safety: Recommendations for Determining Doneness in Consumer Egg Dish Recipes and Measurement of Endpoint Temperatures When Recipes Are Followed.

PubMed

Godwin, Sandria; Maughan, Curtis; Chambers, Edgar

2016-06-23

Many consumers do not follow recommended food safety practices for cooking egg dishes, such as pies, quiches, and casseroles, potentially leading to foodborne illnesses such as Salmonellosis. The United States Department of Agriculture (USDA) recommends cooking egg mixtures until the center reaches 71 °C (160 °F). The objectives of this study were to determine what endpoint temperature information consumers receive from egg dish recipes, and if recipes would lead to safe temperatures when followed. Egg dish recipes ( n = 226) from 65 websites, 50 cookbooks, and nine magazine titles (multiple issues of each) were analyzed. Time was the most frequently used indicator, given in 92% of the recipes, with 15% using only time. Other indicators included: set (89), browned (76), clean toothpick/knife (60), puffed (27), and jiggled (13). Only two recipes indicated final endpoint temperatures. Three recipes (a pie, a quiche, and an egg casserole) were chosen and prepared in triplicate to see if they would reach recommended temperatures. The pie and quiche were still liquid at 71 °C, and were well over the recommended temperature when cooked according to instructions, but the egg casserole was not consistently above 71 °C, when the recipe instructions indicated it was done and the center was light brown and "jiggled" This research indicates that consumers are not receiving information on endpoint temperatures in egg recipes, but the likelihood of foodborne illness is low since most dishes probably be cooked past the recommended temperature before the consumer considers them done unless there are many inclusions that may absorb liquid and reduce the appearance of liquid in the dish.

Food Safety: Recommendations for Determining Doneness in Consumer Egg Dish Recipes and Measurement of Endpoint Temperatures When Recipes Are Followed

PubMed Central

Godwin, Sandria; Maughan, Curtis; Chambers, Edgar

2016-01-01

Many consumers do not follow recommended food safety practices for cooking egg dishes, such as pies, quiches, and casseroles, potentially leading to foodborne illnesses such as Salmonellosis. The United States Department of Agriculture (USDA) recommends cooking egg mixtures until the center reaches 71 °C (160 °F). The objectives of this study were to determine what endpoint temperature information consumers receive from egg dish recipes, and if recipes would lead to safe temperatures when followed. Egg dish recipes (n = 226) from 65 websites, 50 cookbooks, and nine magazine titles (multiple issues of each) were analyzed. Time was the most frequently used indicator, given in 92% of the recipes, with 15% using only time. Other indicators included: set (89), browned (76), clean toothpick/knife (60), puffed (27), and jiggled (13). Only two recipes indicated final endpoint temperatures. Three recipes (a pie, a quiche, and an egg casserole) were chosen and prepared in triplicate to see if they would reach recommended temperatures. The pie and quiche were still liquid at 71 °C, and were well over the recommended temperature when cooked according to instructions, but the egg casserole was not consistently above 71 °C, when the recipe instructions indicated it was done and the center was light brown and “jiggled” This research indicates that consumers are not receiving information on endpoint temperatures in egg recipes, but the likelihood of foodborne illness is low since most dishes probably be cooked past the recommended temperature before the consumer considers them done unless there are many inclusions that may absorb liquid and reduce the appearance of liquid in the dish. PMID:28231140

Communicating projected survival with treatments for chronic kidney disease: patient comprehension and perspectives on visual aids.

PubMed

Dowen, Frances; Sidhu, Karishma; Broadbent, Elizabeth; Pilmore, Helen

2017-09-21

Mortality in end stage renal disease (ESRD) is higher than many malignancies. There is no data about the optimal way to present information about projected survival to patients with ESRD. In other areas, graphs have been shown to be more easily understood than narrative. We examined patient comprehension and perspectives on graphs in communicating projected survival in chronic kidney disease (CKD). One hundred seventy-seven patients with CKD were shown 4 different graphs presenting post transplantation survival data. Patients were asked to interpret a Kaplan Meier curve, pie chart, histogram and pictograph and answer a multi-choice question to determine understanding. We measured interpretation, usefulness and preference for the graphs. Most patients correctly interpreted the graphs. There was asignificant difference in the percentage of correct answers when comparing different graph types (p = 0.0439). The pictograph was correctly interpreted by 81% of participants, the histogram by 79%, pie chart by 77% and Kaplan Meier by 69%. Correct interpretation of the histogram was associated with educational level (p = 0.008) and inversely associated with age > 65 (p = 0.008). Of those who interpreted all four graphs correctly, there was an association with employment (p = 0.001) and New Zealand European ethnicity (p = 0.002). 87% of patients found the graphs useful. The pie chart was the most preferred graph (p 0.002). The readability of the graphs may have been improved with an alternative colour choice, especially in the setting of visual impairment. Visual aids, can be beneficial adjuncts to discussing survival in CKD.

Lactobacillus delbrueckii TUA4408L and its extracellular polysaccharides attenuate enterotoxigenic Escherichia coli-induced inflammatory response in porcine intestinal epitheliocytes via Toll-like receptor-2 and 4.

PubMed

Wachi, Satoshi; Kanmani, Paulraj; Tomosada, Yohsuke; Kobayashi, Hisakazu; Yuri, Toshihito; Egusa, Shintaro; Shimazu, Tomoyuki; Suda, Yoshihito; Aso, Hisashi; Sugawara, Makoto; Saito, Tadao; Mishima, Takashi; Villena, Julio; Kitazawa, Haruki

2014-10-01

Immunobiotics are known to modulate intestinal immune responses by regulating Toll-like receptor (TLR) signaling pathways, which are responsible for the induction of cytokines and chemokines in response to microbial-associated molecular patterns. However, little is known about the immunomodulatory activity of compounds or molecules from immunobiotics. We evaluated whether Lactobacillus delbrueckii subsp. delbrueckii TUA4408L (Ld) or its extracellular polysaccharide (EPS): acidic EPS (APS) and neutral EPS (NPS), modulated the response of porcine intestinal epitheliocyte (PIE) cells against Enterotoxigenic Escherichia coli (ETEC) 987P. The roles of TLR2, TLR4, and TLR negative regulators in the immunoregulatory effects were also studied. ETEC-induced inflammatory cytokines were downregulated when PIE cells were prestimulated with both Ld or EPSs. Ld, APS, and NPS inhibited ETEC mediated mitogen-activated protein kinase (MAPK) and nuclear factor-κB (NF-κB) activation by upregulating TLR negative regulators. The capability of Ld to suppress inflammatory cytokines was diminished when PIE cells were blocked with anti-TLR2 antibody, while APS failed to suppress inflammatory cytokines when cells were treated with anti-TLR4 antibody. Induction of Ca²⁺ fluxes in TLR knockdown cells confirmed that TLR2 plays a principal role in the immunomodulatory action of Ld, while the activity of APS is mediated by TLR4. In addition, NPS activity depends on both TLR4 and TLR2. Ld and its EPS have the potential to be used for the development of anti-inflammatory functional foods to prevent intestinal diseases in both humans and animals. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Nest site preference depends on the relative density of conspecifics and heterospecifics in wild birds.

PubMed

Samplonius, Jelmer M; Kromhout Van Der Meer, Iris M; Both, Christiaan

2017-01-01

Social learning allows animals to eavesdrop on ecologically relevant knowledge of competitors in their environment. This is especially important when selecting a habitat if individuals have relatively little personal information on habitat quality. It is known that birds can use both conspecific and heterospecific information for social learning, but little is known about the relative importance of each information type. If provided with the choice between them, we expected that animals should copy the behaviour of conspecifics, as these confer the best information for that species. We tested this hypothesis in the field for Pied Flycatchers Ficedula hypoleuca arriving at their breeding grounds to select a nest box for breeding. We assigned arbitrary symbols to nest boxes of breeding pied flycatchers (conspecifics) and blue and great tits, Cyanistes caeruleus and Parus major (heterospecifics), in 2014 and 2016 in two areas with different densities of tits and flycatchers. After ca 50% of flycatchers had returned and a flycatcher symbol was assigned to their nest box, we gave the later arriving flycatchers the choice between empty nest boxes with either a conspecific (flycatcher) or a heterospecific (tit) symbol. As expected, Pied Flycatchers copied the perceived nest box choice of conspecifics, but only in areas that were dominated by flycatchers. Against our initial expectation, flycatchers copied the perceived choice of heterospecifics in the area heavily dominated by tits, even though conspecific minority information was present. Our results confirm that the relative density of conspecifics and heterospecifics modulates the propensity to copy or reject novel behavioural traits. By contrasting conspecific and heterospecific ecology in the same study design we were able to draw more general conclusions about the role of fluctuating densities on social information use.

An Algorithmic, Pie-Crusting Medial Soft Tissue Release Reduces the Need for Constrained Inserts Patients With Severe Varus Deformity Undergoing Total Knee Arthroplasty.

PubMed

Goudarz Mehdikhani, Kaveh; Morales Moreno, Beatriz; Reid, Jeremy J; de Paz Nieves, Ana; Lee, Yuo-Yu; González Della Valle, Alejandro

2016-07-01

We studied the need to use a constrained insert for residual intraoperative instability and the 1-year result of patients undergoing total knee arthroplasty (TKA) for a varus deformity. In a control group, a "classic" subperiosteal release of the medial soft tissue sleeve was performed as popularized by pioneers of TKA. In the study group, an algorithmic approach that selectively releases and pie-crusts posteromedial structures in extension and anteromedial structures in flexion was used. All surgeries were performed by a single surgeon using measured resection technique, and posterior-stabilized, cemented implants. There were 228 TKAs in the control group and 188 in the study group. Outcome variables included the use of a constrained insert, and the Knee Society Score at 6 weeks, 4 months, and 1 year postoperatively. The effect of the release technique on use of constrained inserts and clinical outcomes were analyzed in a multivariate model controlling for age, sex, body mass index, and severity of deformity. The use of constrained inserts was significantly lower in study than in control patients (8% vs 18%; P = .002). There was no difference in the Knee Society Score and range of motion between the groups at last follow-up. No patient developed postoperative medial instability. This algorithmic, pie-crusting release technique resulted in a significant reduction in the use of constrained inserts with no detrimental effects in clinical results, joint function, and stability. As constrained TKA implants are more costly than nonconstrained ones, if the adopted technique proves to be safe in the long term, it may cause a positive shift in value for hospitals and cost savings in the health care system. Copyright © 2016 Elsevier Inc. All rights reserved.

Reynolds number effects in combustion noise

NASA Technical Reports Server (NTRS)

Seshan, P. K.

1981-01-01

Acoustic emission spectra have been obtained for non-premixed turbulent combustion from two small diameter laboratory gas burners, two commercial gas burners and a large gas burner in the firebox of a Babcock-Wilcox Boiler (50,000 lb steam/hr). The changes in burner size and firing rate represent changes in Reynolds number and changes in air/fuel ratio represent departure from stoichiometric proportions. The combustion efficiency was measured independently through gas analysis. The acoustic spectra obtained from the various burners exhibit a persistent shape over the Reynolds number range of 8200-82,000. The spectra were analyzed for identification of a predictable frequency domain that is most responsive to, and readily correlated with, combustion efficiency. A simple parameter (consisting of the ratio of the average acoustic power output in the most responsive frequency bandwidth to the acoustic power level of the loudest frequency) is proposed whose value increases significantly and unmistakably as combustion efficiency approaches 100%. The dependence of the most responsive frequency domain on the various Reynolds numbers associated with turbulent jets is discussed.

Managed care's Achilles heel: ethical immaturity.

PubMed

Thompson, R E

2000-01-01

How can physician executives determine the prevailing values in the managed care arena? What are the consequences when values statements are ignored during decision-making? These questions can be answered using a process called ethical reasoning, which is different and more productive than making moral judgments, such as "is managed care good or bad?" Failing to include ethical reasoning in executive offices and boardrooms is a form of ethical immaturity. It fuels public suspicion that managed care's goal may be maximizing profit at all costs, as opposed to seeking reasonable profit through provision of dependable and accessible health care services. One outcome of ethical reasoning is rediscovering the basic truth that running one's business on competitive rather than altruistic principles is ethical whenever greater efficiencies and economic growth enlarge the size of the pie for everyone. Reasonable self-interest is a perfectly acceptable reason to act ethically. The time has come for physician executives to develop a basic understanding of pragmatic ethics, and to appreciate the value of adding ethical reasoning to the decision-making process.

DETECTORS AND EXPERIMENTAL METHODS: Measurement of the response function and the detection efficiency of an organic liquid scintillator for neutrons between 1 and 30 MeV

NASA Astrophysics Data System (ADS)

Huang, Han-Xiong; Ruan, Xi-Chao; Chen, Guo-Chang; Zhou, Zu-Ying; Li, Xia; Bao, Jie; Nie, Yang-Bo; Zhong, Qi-Ping

2009-08-01

The light output function of a varphi50.8 mm × 50.8 mm BC501A scintillation detector was measured in the neutron energy region of 1 to 30 MeV by fitting the pulse height (PH) spectra for neutrons with the simulations from the NRESP code at the edge range. Using the new light output function, the neutron detection efficiency was determined with two Monte-Carlo codes, NEFF and SCINFUL. The calculated efficiency was corrected by comparing the simulated PH spectra with the measured ones. The determined efficiency was verified at the near threshold region and normalized with a Proton-Recoil-Telescope (PRT) at the 8-14 MeV energy region.

The Economics of Information: A Classroom Experiment.

ERIC Educational Resources Information Center

Netusil, Noelwah R.; Haupert, Michael

1995-01-01

Describes an economics class experiment where students ranked the quality of baked pies according to limited information. The limited sets of information included brand name and packaging only, price only, advertising only, word-of-mouth, and taste test. Discusses signals of quality and consumer decisions. (MJP)

The Effects of Predictability on Stress and Immune Function

DTIC Science & Technology

1993-06-24

number of cups ______________ _ Chocolate, cocoa, wine, beer/alcohol, decaffeinated coffee. Breads containing raisins, prunes, orange peel , banana or...pudding,. mince pie ••••• ) Banana , avocado, pineapple, canned figs, raisins, plums and prune •• Orange., orange juice, fruit cocktail with pineapple

21 CFR 172.120 - Calcium disodium EDTA.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., nonstandardized 75 Preservative. Dried lima beans (cooked canned) 310 Promote color retention. Egg product that is... cooked canned, other than dried lima beans, pink beans, and red beans) 365 Promote color retention... pie filling 100 Promote color retention. Pink beans (cooked canned) 165 Promote color retention...

21 CFR 172.120 - Calcium disodium EDTA.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., nonstandardized 75 Preservative. Dried lima beans (cooked canned) 310 Promote color retention. Egg product that is... cooked canned, other than dried lima beans, pink beans, and red beans) 365 Promote color retention... pie filling 100 Promote color retention. Pink beans (cooked canned) 165 Promote color retention...

40. Detail of typical subdeck of granite pier showing humanscale ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

40. Detail of typical subdeck of granite pier showing human-scale arched openings in pies. Note remnants of fender system. View north - New York, New Haven & Hartford Railroad, Fort Point Channel Rolling Lift Bridge, Spanning Fort Point Channel, Boston, Suffolk County, MA

Recurrent Education: "Apple Pie" ...or..."Atomic Bomb"?

ERIC Educational Resources Information Center

Day, William L.

The author conceptualizes recurrent education as organized, structured, institutionally sponsored learning activities with intentional outcomes, which are distributed over the life span of the individual in a recurring way. Some problems to which recurrent education proposes solutions include: alienation at the inter-generational level,…

Game theoretic approaches to operating room management.

PubMed

Marco, Alan P

2002-05-01

All interactions between people can be considered games with rules and outcomes. However, modern business practices demand that the players in the game go beyond traditional game theory and look at new ways to improve the outcome of the game. Choosing the right strategy is important to a player's success. A new business strategy, "co-opetition," can be used to increase the value of the game ("create a bigger pie") through cooperative behavior, whereas competition is used to divided the "pie." By looking at how the players adopt simultaneous roles such as complementor and competitor the stakeholders in the operating room (managers, surgeons, anesthesiologists, and nursing staff) can apply the principles of co-opetition to improve the overall success of their facility. Such stakeholders can utilize knowledge of how populations act in games to enhance cooperative play. Adopting such a perspective may lead to increases in the satisfaction and morale of those involved with the operating rooms. Increased morale should increase productivity and staff retention and reduce recruiting needs.

[Visual input affects the expression of the early genes c-Fos and ZENK in auditory telencephalic centers of pied flycatcher nestlings during the acoustically-guided freezing].

PubMed

Korneeva, E V; Tiunova, A A; Aleksandrov, L I; Golubeva, T B; Anokhin, K V

2014-01-01

The present study analyzed expression of transcriptional factors c-Fos and ZENK in 9-day-old pied flycatcher nestlings' (Ficedula hypoleuca) telencephalic auditory centers (field L, caudomedial nidopallium and caudomedial mesopallium) involved in the acoustically-guided defense behavior. Species-typical alarm call was presented to the young in three groups: 1--intact group (sighted control), 2--nestlings visually deprived just before the experiment for a short time (unsighted control) 3--nestlings visually deprived right after hatching (experimental deprivation). Induction of c-Fos as well as ZENK in nestlings from the experimental deprivation group was decreased in both hemispheres as compared with intact group. In the group of unsighted control, only the decrease of c-Fos induction was observed exclusively in the right hemisphere. These findings suggest that limitation of visual input changes the population of neurons involved into the acoustically-guided behavior, the effect being dependant from the duration of deprivation.

Post-irradiation examinations of Li 4SiO 4 pebbles irradiated in the EXOTIC-7 experiment

NASA Astrophysics Data System (ADS)

Piazza, G.; Scaffidi-Argentina, F.; Werle, H.

2000-12-01

Extraction of tritium in ceramics-7 (EXOTIC-7) was the first in-pile test with 6Li-enriched (50%) lithium orthosilicate (Li 4SiO 4) pebbles and with DEMO representative Li-burnup. Post-irradiation examinations (PIEs) of the Li 4SiO 4 have been performed at the Forschungszentrum Karlsruhe (FZK) to investigate the tritium release kinetics, the effects of Li-burnup, of the contact with beryllium during irradiation and the changes in the mechanical stability of the pebbles due to irradiation. Based on these data one can conclude that neither the contact with beryllium nor a burnup up to 13% have a detrimental effect on the tritium release of Li 4SiO 4 pebbles, but at 18% Li-burnup the residence time is increased by about a factor of 3. The mechanical strength of both irradiated and unirradiated pebbles has been examined by means of crush tests. According to the PIE no significant changes in the mechanical stability of the pebbles have been observed.

SPICE: exploration and analysis of post-cytometric complex multivariate datasets.

PubMed

Roederer, Mario; Nozzi, Joshua L; Nason, Martha C

2011-02-01

Polychromatic flow cytometry results in complex, multivariate datasets. To date, tools for the aggregate analysis of these datasets across multiple specimens grouped by different categorical variables, such as demographic information, have not been optimized. Often, the exploration of such datasets is accomplished by visualization of patterns with pie charts or bar charts, without easy access to statistical comparisons of measurements that comprise multiple components. Here we report on algorithms and a graphical interface we developed for these purposes. In particular, we discuss thresholding necessary for accurate representation of data in pie charts, the implications for display and comparison of normalized versus unnormalized data, and the effects of averaging when samples with significant background noise are present. Finally, we define a statistic for the nonparametric comparison of complex distributions to test for difference between groups of samples based on multi-component measurements. While originally developed to support the analysis of T cell functional profiles, these techniques are amenable to a broad range of datatypes. Published 2011 Wiley-Liss, Inc.

Pie-like electrode design for high-energy density lithium–sulfur batteries

PubMed Central

Li, Zhen; Zhang, Jin Tao; Chen, Yu Ming; Li, Ju; Lou, Xiong Wen (David)

2015-01-01

Owing to the overwhelming advantage in energy density, lithium–sulfur (Li–S) battery is a promising next-generation electrochemical energy storage system. Despite many efforts in pursuing long cycle life, relatively little emphasis has been placed on increasing the areal energy density. Herein, we have designed and developed a ‘pie' structured electrode, which provides an excellent balance between gravimetric and areal energy densities. Combining lotus root-like multichannel carbon nanofibers ‘filling' and amino-functionalized graphene ‘crust', the free-standing paper electrode (S mass loading: 3.6 mg cm−2) delivers high specific capacity of 1,314 mAh g−1 (4.7 mAh cm−2) at 0.1 C (0.6 mA cm−2) accompanied with good cycling stability. Moreover, the areal capacity can be further boosted to more than 8 mAh cm−2 by stacking three layers of paper electrodes with S mass loading of 10.8 mg cm−2. PMID:26608228

Finite-beta equilibria for Wendelstein 7-X configurations using the Princeton Iterative Equilibrium Solver code

NASA Astrophysics Data System (ADS)

Arndt, S.; Merkel, P.; Monticello, D. A.; Reiman, A. H.

1999-04-01

Fixed- and free-boundary equilibria for Wendelstein 7-X (W7-X) [W. Lotz et al., Plasma Physics and Controlled Nuclear Fusion Research 1990 (Proc. 13th Int. Conf. Washington, DC, 1990), (International Atomic Energy Agency, Vienna, 1991), Vol. 2, p. 603] configurations are calculated using the Princeton Iterative Equilibrium Solver (PIES) [A. H. Reiman et al., Comput. Phys. Commun., 43, 157 (1986)] to deal with magnetic islands and stochastic regions. Usually, these W7-X configurations require a large number of iterations for PIES convergence. Here, two methods have been successfully tested in an attempt to decrease the number of iterations needed for convergence. First, periodic sequences of different blending parameters are used. Second, the initial guess is vastly improved by using results of the Variational Moments Equilibrium Code (VMEC) [S. P. Hirshmann et al., Phys. Fluids 26, 3553 (1983)]. Use of these two methods have allowed verification of the Hamada condition and tendency of "self-healing" of islands has been observed.

Detection of spectroscopic binaries: lessons from the Gaia-ESO survey

NASA Astrophysics Data System (ADS)

van der Swaelmen, Mathieu; Merle, Thibault; van Eck, Sophie; Jorissen, Alain; Zwitter, Tomaž

2018-04-01

The Gaia-ESO survey (GES; Gilmore et al. (2012), Randich et al. (2013)) is a spectroscopic survey complementing the Gaia mission to bring accurate radial velocities and chemical abundances for 105 stars. Merle et al. (submitted to A&A see also this volume) developped a tool (DOE) to detect multiple peaks in the cross-correlation functions (CCFs) of GES spectra. Using the GIRAFFE HR10 and HR21 settings, we were able to compare the efficiency of our SB detection tool depending on the wavelength range and resolution. We show that a careful design of CCF masks can improve the detection rate in the HR21 settings. HR21 spectra are similar to the ones produced by the RVS spectrograph of the Gaia mission, though the lower resolution of RVS spectra may result in a lower detection efficiency than the case of HR21. Analysis of RVS spectra in the context of spectroscopic binaries can take advantage of the lessons learnt from the GES to maximize the detection rate.

Relation of exact Gaussian basis methods to the dephasing representation: Theory and application to time-resolved electronic spectra

NASA Astrophysics Data System (ADS)

Sulc, Miroslav; Hernandez, Henar; Martinez, Todd J.; Vanicek, Jiri

2014-03-01

We recently showed that the Dephasing Representation (DR) provides an efficient tool for computing ultrafast electronic spectra and that cellularization yields further acceleration [M. Šulc and J. Vaníček, Mol. Phys. 110, 945 (2012)]. Here we focus on increasing its accuracy by first implementing an exact Gaussian basis method (GBM) combining the accuracy of quantum dynamics and efficiency of classical dynamics. The DR is then derived together with ten other methods for computing time-resolved spectra with intermediate accuracy and efficiency. These include the Gaussian DR (GDR), an exact generalization of the DR, in which trajectories are replaced by communicating frozen Gaussians evolving classically with an average Hamiltonian. The methods are tested numerically on time correlation functions and time-resolved stimulated emission spectra in the harmonic potential, pyrazine S0 /S1 model, and quartic oscillator. Both the GBM and the GDR are shown to increase the accuracy of the DR. Surprisingly, in chaotic systems the GDR can outperform the presumably more accurate GBM, in which the two bases evolve separately. This research was supported by the Swiss NSF Grant No. 200021_124936/1 and NCCR Molecular Ultrafast Science & Technology (MUST), and by the EPFL.

An efficient algorithm for automatic phase correction of NMR spectra based on entropy minimization

NASA Astrophysics Data System (ADS)

Chen, Li; Weng, Zhiqiang; Goh, LaiYoong; Garland, Marc

2002-09-01

A new algorithm for automatic phase correction of NMR spectra based on entropy minimization is proposed. The optimal zero-order and first-order phase corrections for a NMR spectrum are determined by minimizing entropy. The objective function is constructed using a Shannon-type information entropy measure. Entropy is defined as the normalized derivative of the NMR spectral data. The algorithm has been successfully applied to experimental 1H NMR spectra. The results of automatic phase correction are found to be comparable to, or perhaps better than, manual phase correction. The advantages of this automatic phase correction algorithm include its simple mathematical basis and the straightforward, reproducible, and efficient optimization procedure. The algorithm is implemented in the Matlab program ACME—Automated phase Correction based on Minimization of Entropy.

Non-Markovian Quantum State Diffusion for temperature-dependent linear spectra of light harvesting aggregates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ritschel, Gerhard; Möbius, Sebastian; Eisfeld, Alexander, E-mail: eisfeld@mpipks-dresden.mpg.de

2015-01-21

Non-Markovian Quantum State Diffusion (NMQSD) has turned out to be an efficient method to calculate excitonic properties of aggregates composed of organic chromophores, taking into account the coupling of electronic transitions to vibrational modes of the chromophores. NMQSD is an open quantum system approach that incorporates environmental degrees of freedom (the vibrations in our case) in a stochastic way. We show in this paper that for linear optical spectra (absorption, circular dichroism), no stochastics is needed, even for finite temperatures. Thus, the spectra can be obtained by propagating a single trajectory. To this end, we map a finite temperature environmentmore » to the zero temperature case using the so-called thermofield method. The resulting equations can then be solved efficiently by standard integrators.« less

ASERA: A spectrum eye recognition assistant for quasar spectra

NASA Astrophysics Data System (ADS)

Yuan, Hailong; Zhang, Haotong; Zhang, Yanxia; Lei, Yajuan; Dong, Yiqiao; Zhao, Yongheng

2013-11-01

Spectral type recognition is an important and fundamental step of large sky survey projects in the data reduction for further scientific research, like parameter measurement and statistic work. It tends out to be a huge job to manually inspect the low quality spectra produced from the massive spectroscopic survey, where the automatic pipeline may not provide confident type classification results. In order to improve the efficiency and effectiveness of spectral classification, we develop a semi-automated toolkit named ASERA, ASpectrum Eye Recognition Assistant. The main purpose of ASERA is to help the user in quasar spectral recognition and redshift measurement. Furthermore it can also be used to recognize various types of spectra of stars, galaxies and AGNs (Active Galactic Nucleus). It is an interactive software allowing the user to visualize observed spectra, superimpose template spectra from the Sloan Digital Sky Survey (SDSS), and interactively access related spectral line information. It is an efficient and user-friendly toolkit for the accurate classification of spectra observed by LAMOST (the Large Sky Area Multi-object Fiber Spectroscopic Telescope). The toolkit is available in two modes: a Java standalone application and a Java applet. ASERA has a few functions, such as wavelength and flux scale setting, zoom in and out, redshift estimation, spectral line identification, which helps user to improve the spectral classification accuracy especially for low quality spectra and reduce the labor of eyeball check. The function and performance of this tool is displayed through the recognition of several quasar spectra and a late type stellar spectrum from the LAMOST Pilot survey. Its future expansion capabilities are discussed.

Computer simulation of magnetic resonance spectra employing homotopy.

PubMed

Gates, K E; Griffin, M; Hanson, G R; Burrage, K

1998-11-01

Multidimensional homotopy provides an efficient method for accurately tracing energy levels and hence transitions in the presence of energy level anticrossings and looping transitions. Herein we describe the application and implementation of homotopy to the analysis of continuous wave electron paramagnetic resonance spectra. The method can also be applied to electron nuclear double resonance, electron spin echo envelope modulation, solid-state nuclear magnetic resonance, and nuclear quadrupole resonance spectra. Copyright 1998 Academic Press.

Making Sense of Fractions and Percentages

ERIC Educational Resources Information Center

Whitin, David J.; Whitin, Phyllis

2012-01-01

Because fractions and percentages can be difficult for children to grasp, connecting them whenever possible is beneficial. Linking them can foster representational fluency as children simultaneously see the part-whole relationship expressed numerically (as a fraction and as a percentage) and visually (as a pie chart). NCTM advocates these…

Life of Pizza Pie: The Implications of Sub-Group Comparisons in Education

ERIC Educational Resources Information Center

Thomas, Tara N.

2013-01-01

Current educational statistics have pitted subgroups against one another without consideration of the actual population sizes of each group. This paper is intended to provided a clearer understanding of the current usage of sub-group comparisons in American education. (Contains 4 figures.)

Improving Relationships: Serving up a Slice of "Enemy Pie"

ERIC Educational Resources Information Center

Hall, P. Cougar; McIntyre, Emily

2011-01-01

The "14 Characteristics of Effective Health Education Curricula" identified by the Centers for Disease Control and Prevention, Division of Adolescent and School Health promote teaching ideas designed to personalize information and engage students through activities which are both student centered and interactive. Effective health education efforts…

Rules and Responsibilities.

ERIC Educational Resources Information Center

Henderson, Meredith

1988-01-01

Presents two lessons for grades 1-4 which help students understand responsibility by considering situations from children's literature; in this case, THE PIED PIPER OF HAMELIN by Browning and FANTASTIC MR. FOX by Dahl. Provides discussion questions, suggestions for role playing, and a mock trial activity which involves students with visiting…

TEMPORAL VARIABILITY IN BASAL ISOPRENE EMISSION FACTOR

EPA Science Inventory

Seasonal variability in basal isoprene emission factor (micrograms C /g hr or nmol/ m2 sec, leaf temperature at 30 degrees C and photosynthetically active radiation (PAR) at 1000 micromol/ m2 sec) was studied during the 1998 growing season at Duke Forest in the North Carolina Pie...

Project International Emphasis Interim Report, July 1991.

ERIC Educational Resources Information Center

Blois, Beverly, Ed.; Williams, Barbara

Project International Emphasis (PIE), a curriculum development effort involving all 24 colleges in the Virginia Community College System (VCCS), focuses on the infusion of globally oriented components across the academic curriculum and in related career development programs. Activities undertaken during the project's first year included an annual…

The Area of a Circle

ERIC Educational Resources Information Center

Greenslade, Thomas B., Jr.

2011-01-01

The geometrical shapes in Fig. 1 recently came into the Greenslade Collection. The semi-triangular pieces of wood looked like slices from a pie, each 22.5 degrees in angular width. They were tied together with a thin leather band tacked around their curved surfaces. What is this apparatus?

A sensitive continuum analysis method for gamma ray spectra

NASA Technical Reports Server (NTRS)

Thakur, Alakh N.; Arnold, James R.

1993-01-01

In this work we examine ways to improve the sensitivity of the analysis procedure for gamma ray spectra with respect to small differences in the continuum (Compton) spectra. The method developed is applied to analyze gamma ray spectra obtained from planetary mapping by the Mars Observer spacecraft launched in September 1992. Calculated Mars simulation spectra and actual thick target bombardment spectra have been taken as test cases. The principle of the method rests on the extraction of continuum information from Fourier transforms of the spectra. We study how a better estimate of the spectrum from larger regions of the Mars surface will improve the analysis for smaller regions with poorer statistics. Estimation of signal within the continuum is done in the frequency domain which enables efficient and sensitive discrimination of subtle differences between two spectra. The process is compared to other methods for the extraction of information from the continuum. Finally we explore briefly the possible uses of this technique in other applications of continuum spectra.

Bayesian reconstruction of projection reconstruction NMR (PR-NMR).

PubMed

Yoon, Ji Won

2014-11-01

Projection reconstruction nuclear magnetic resonance (PR-NMR) is a technique for generating multidimensional NMR spectra. A small number of projections from lower-dimensional NMR spectra are used to reconstruct the multidimensional NMR spectra. In our previous work, it was shown that multidimensional NMR spectra are efficiently reconstructed using peak-by-peak based reversible jump Markov chain Monte Carlo (RJMCMC) algorithm. We propose an extended and generalized RJMCMC algorithm replacing a simple linear model with a linear mixed model to reconstruct close NMR spectra into true spectra. This statistical method generates samples in a Bayesian scheme. Our proposed algorithm is tested on a set of six projections derived from the three-dimensional 700 MHz HNCO spectrum of a protein HasA. Copyright © 2014 Elsevier Ltd. All rights reserved.

Spectra of black hole accretion models of ultraluminous X-ray sources

NASA Astrophysics Data System (ADS)

Narayan, Ramesh; Sa̧dowski, Aleksander; Soria, Roberto

2017-08-01

We present general relativistic radiation magnetohydrodynamics simulations of super-Eddington accretion on a 10 M⊙ black hole. We consider a range of mass accretion rates, black hole spins and magnetic field configurations. We compute the spectra and images of the models as a function of viewing angle and compare them with the observed properties of ultraluminous X-ray sources (ULXs). The models easily produce apparent luminosities in excess of 1040 erg s-1 for pole-on observers. However, the angle-integrated radiative luminosities rarely exceed 2.5 × 1039 erg s-1 even for mass accretion rates of tens of Eddington. The systems are thus radiatively inefficient, though they are energetically efficient when the energy output in winds and jets is also counted. The simulated models reproduce the main empirical types of spectra - disc-like, supersoft, soft, hard - observed in ultraluminous X-ray sources (ULXs). The magnetic field configuration, whether 'standard and normal evolution' (SANE) or 'magnetically arrested disc' (MAD), has a strong effect on the results. In SANE models, the X-ray spectral hardness is almost independent of accretion rate, but decreases steeply with increasing inclination. MAD models with non-spinning black holes produce significantly softer spectra at higher values of \\dot{M}, even at low inclinations. MAD models with rapidly spinning black holes are unique. They are radiatively efficient (efficiency factor ˜10-20 per cent), superefficient when the mechanical energy output is also included (70 per cent) and produce hard blazar-like spectra. In all models, the emission shows strong geometrical beaming, which disagrees with the more isotropic illumination favoured by observations of ULX bubbles.

Impact of pentacene film thickness on the photoresponse spectra: Determination of the photocarrier generation mechanism

NASA Astrophysics Data System (ADS)

Gorgolis, S.; Giannopoulou, A.; Anastassopoulos, D.; Kounavis, P.

2012-07-01

Photocurrent response, optical absorption, and x-ray diffraction (XRD) measurements in pentacene films grown on glass substrates are performed in order to obtain an insight into the mobile photocarriers generation mechanism. For film thickness of the order of 50 nm and lower, the photocurrent response spectra are found to follow the optical absorption spectra demonstrating the so-called symbatic response. Upon increasing the film thickness, the photoresponse demonstrates a transition to the so-called antibatic response, which is characterized by a maximum and minimum photocurrent for photon energies of minimum and maximum optical absorption, respectively. The experimental results are not in accordance with the model of important surface recombination rate. By taking into account the XRD patterns, the experimental photoresponse spectra can be reproduced by model simulations assuming efficient exciton dissociation at a narrow layer of the order of 20 nm near the pentacene-substrate interface. The simulated spectra are found sensitive to the film thickness, the absolute optical absorption coefficient, and the diffusion exciton length. By comparing the experimental with the simulated spectra, it is deduced that the excitons, which are created by optical excitation in the spectral region of 1.7-2.2 eV, diffuse with a diffusion length of the order of 10-80 nm to the pentacene-substrate interface where efficiently dissociate into mobile charge carriers.

Effect of green light spectra on the reduction of retinal damage and stress in goldfish, Carassius auratus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, Jin Ah; Kim, Na Na; Choi, Young Jae

We investigated the effect of light spectra on retinal damage and stress in goldfish using green (530 nm) and red (620 nm) light emitting diodes (LEDs) at three intensities each (0.5, 1.0, and 1.5 W/m{sup 2}). We measured the change in the levels of plasma cortisol and H{sub 2}O{sub 2} and expression and levels of caspase-3. The apoptotic response of green and red LED spectra was assessed using the terminal transferase dUTP nick end labeling (TUNEL) assay. Stress indicator (cortisol and H{sub 2}O{sub 2}) and apoptosis-related genes (caspase-3) decreased in green light, but increased in red light with higher light intensities over time.more » The TUNEL assay revealed that more apoptotic cells were detected in outer nuclear layers after exposure to red LED over time with the increase in light intensity, than the other spectra. These results indicate that green light efficiently reduces retinal damage and stress, whereas red light induces it. Therefore, red light-induced retina damage may induce apoptosis in goldfish retina. -- Highlights: •Green light efficiently reduces retinal damage and stress. •Green spectra reduce caspase production and apoptosis. •Red light-induced retina damage may induce apoptosis in goldfish retina. •The retina of goldfish recognizes green spectra as a stable environment.« less

Government - Prime Contractor - Subcontractor Relationships: An Analysis.

DTIC Science & Technology

1979-12-01

contract, prime contractor frustration and animosity due to over zealous 122 JAM ,- Government managers, and subcontractor problems of "over- reach" and...Journal, Vol. 12, No. 2,Second Quarter, 1978. 41. Singer, N.P., "The Unheard of Standard Set of Sub- contract Terms and Conditions - As Easy as Pumpkin Pie

Pharmaceuticals and the Environment (PiE): Evolution and impact of the published literature revealed by bibliometric analysis

EPA Science Inventory

The evolution and impact of the published literature surrounding the transdisciplinary, multifaceted topic of pharmaceuticals as contaminants in the environment is examined for the first time in an historical context. The preponderance of literature cited in this examination repr...

Voluntary Green Power Procurement | Energy Analysis | NREL

Science.gov Websites

state renewable portfolio standards (RPSs). Pie chart depicting the voluntary market share of non -hydropower renewable generation. And, chart depicting the voluntary market share of non-hydropower renewable generation over time, from 2006 to 2015. Voluntary market share of U.S. non-hydropower renewable generation

Changing Public Perceptions of Higher Ed

ERIC Educational Resources Information Center

Harney, John O.

2018-01-01

The benefits of going to college and the importance of higher education institutions were once held to be a creed as American as apple pie. But recurring state budget challenges have constrained investment. Consistently rising tuitions--fueled by increasing college costs--have alarmed many. Politics and free-speech controversies have raised…

Measures of School Integration: Comparing Coleman's Index to Measures of Species Diversity.

ERIC Educational Resources Information Center

Mercil, Steven Bray; Williams, John Delane

This study used species diversity indices developed in ecology as a measure of socioethnic diversity, and compared them to Coleman's Index of Segregation. The twelve indices were Simpson's Concentration Index ("ell"), Simpson's Index of Diversity, Hurlbert's Probability of Interspecific Encounter (PIE), Simpson's Probability of…

"Pork Pies and Vindaloos": Learning for Cosmopolitan Citizenship

ERIC Educational Resources Information Center

Sharpe, Darren Miguel

2018-01-01

This paper examines Audrey Osler and Hugh Starkey's 2003 article on cosmopolitan citizenship 14 years after its publication. Since its publication, young people's disconnection from political life has increasingly become a cause for concern for most, if not all, Western democracies. Specifically, this article examines the implications for young…

75 FR 38112 - Organization, Functions, and Delegations of Authority; Part G; Indian Health Service; Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Indian Health Service Organization, Functions, and... Ethics Staff (PIES) (GAL1) (1) Directs the fact-finding and resolution of allegations of impropriety such as mismanagement of resources, fraud, waste, and abuse, violations of the Standards of Ethical...

Resolving resource conflict: A bigger pie

Treesearch

Jim Winder

1999-01-01

One of today's critical questions for ranchers is how to gain economic benefits from natural resources without damaging biodiversity. Ranchers today face declining beef prices, escalating resource prices, and taking on costs once covered outside the industry. Ranchers join environmentalists and agency personnel in the struggle to meet evolving needs of the...

Sweet Conclusion

ERIC Educational Resources Information Center

Shirley, Britt M.; Wooldridge, Barbara Ross; Camp, Kerri M.

2012-01-01

Jen Harrington is the owner and pastry chef of Sweet Conclusion, a bakery in Tampa, Florida. Most of Harrington's business comes from baking wedding cakes, but she has been attempting to attract customers to her retail bakery, where she sells cupcakes, pies, ice cream, and coffee. Nearly four years she opened Sweet Conclusion, the retail part of…

Creative Photography - Wildlife

NASA Image and Video Library

2016-03-25

A pied-billed grebe paddles in one of the many waterways at Merritt Island National Wildlife Refuge in Florida. NASA’s Kennedy Space Center shares boundaries with the refuge, which is home to more than 330 native and migratory bird species, along with 25 mammal, 117 fish, and 65 amphibian and reptile species.

Engineered and Other Wood Products - An Opportunity to "Grow the Pie"

Treesearch

Albert Schuler; Craig Adair

2003-01-01

The market for engineered wood products (EWP) is being driven by a number of factors including: technology; reduced availability of old-growth timber; construction activity, and globalization. Specifically, technological developments have allowed the industry to "engineer" or "design" improved performance properties and to utilize former "weed...

KSC-2011-1019

NASA Image and Video Library

2011-01-05

CAPE CANAVERAL, Fla. -- A Pied-billed grebe wades through brackish water just north of the Shuttle Landing Facility at NASA's Kennedy Space Center in Florida. Kennedy coexists with the Merritt Island National Wildlife Refuge, habitat to more than 310 species of birds, 25 mammals, 117 fish and 65 amphibians and reptiles. Photo credit: NASA/Frankie Martin

An Inquiry into Differences in Patient Outcomes by Observing Dietitian and Nurse Practitioner Management of Hyperlipidemia

DTIC Science & Technology

1987-07-01

excluded fats Breads and Cereals: Breads Commercial biscuits, muffins, #-Whole wheat cornbread, cakes, cake mixes, -Rye cookies , fried pies, cupcakes...Oatmeal *Chips -Pumpernickle Egg Bread -French rolls Cheese Bread #-English muffins (whole wheat) Commercial mixes containing -Sour dough bread dried

Crazy Patchwork Clay Bowl

ERIC Educational Resources Information Center

Hobbs, Janice

2007-01-01

Crazy patchwork quilts, which inspired this bowl, are as American as apple pie. In 1876, the Philadelphia Centennial Exposition opened and the American society fell instantly in love with Japanese ceramics and asymmetrical art. Victorian ladies incorporated the idea of asymmetrical design into their quilts, which became known as crazy quilts. The…

48 CFR 809.106-1 - Conditions for pre-award surveys.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for contracts covering the products and services of the following: (1) Bakeries. (2) Dairies. (3) Ice cream plants. (4) Laundry and dry cleaning activities. (b) Before any inspection, the contracting... open market purchase of fresh bakery products (such as pies, cakes, and cookies), VA will inspect and...

48 CFR 809.106-1 - Conditions for pre-award surveys.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for contracts covering the products and services of the following: (1) Bakeries. (2) Dairies. (3) Ice cream plants. (4) Laundry and dry cleaning activities. (b) Before any inspection, the contracting... open market purchase of fresh bakery products (such as pies, cakes, and cookies), VA will inspect and...

48 CFR 809.106-1 - Conditions for pre-award surveys.

Code of Federal Regulations, 2013 CFR

2013-10-01

... for contracts covering the products and services of the following: (1) Bakeries. (2) Dairies. (3) Ice cream plants. (4) Laundry and dry cleaning activities. (b) Before any inspection, the contracting... open market purchase of fresh bakery products (such as pies, cakes, and cookies), VA will inspect and...

48 CFR 809.106-1 - Conditions for pre-award surveys.

Code of Federal Regulations, 2014 CFR

2014-10-01

... for contracts covering the products and services of the following: (1) Bakeries. (2) Dairies. (3) Ice cream plants. (4) Laundry and dry cleaning activities. (b) Before any inspection, the contracting... open market purchase of fresh bakery products (such as pies, cakes, and cookies), VA will inspect and...

Trash Pie: Is Your School Serving?

ERIC Educational Resources Information Center

Hoover, Krista M.; Curran, Mary Carla

2010-01-01

In observation of Earth Day, third-grade students were invited to examine what they contribute to the landfill and learn new ways they could help protect the environment. In this lesson, students collected, evaluated, and displayed data comparing the trash generated by home-lunch versus school-lunch students. Students interpreted their findings…

Visual Literacy, Creativity and the Teaching of Argument

ERIC Educational Resources Information Center

Shivers, James; Levenson, Cyra; Tan, Mei

2017-01-01

A vibrant theory of change capable of fueling critical practice may be an indispensable feature of teaching argument in secondary education. According to the PIE model (Perception, Interpretation, Expression), layers of experience build a cognitive scaffold to support the development of critical skills. In addition, incorporating works of art and…

PSA discriminator influence on (222)Rn efficiency detection in waters by liquid scintillation counting.

PubMed

Stojković, Ivana; Todorović, Nataša; Nikolov, Jovana; Tenjović, Branislava

2016-06-01

A procedure for the (222)Rn determination in aqueous samples using liquid scintillation counting (LSC) was evaluated and optimized. Measurements were performed by ultra-low background spectrometer Quantulus 1220™ equipped with PSA (Pulse Shape Analysis) circuit which discriminates alpha/beta spectra. Since calibration procedure is carried out with (226)Ra standard, which has both alpha and beta progenies, it is clear that PSA discriminator has vital importance in order to provide precise spectra separation. Improvement of calibration procedure was done through investigation of PSA discriminator level and, consequentially, the activity of (226)Ra calibration standard influence on (222)Rn efficiency detection. Quench effects on generated spectra i.e. determination of radon efficiency detection were also investigated with quench calibration curve obtained. Radon determination in waters based on modified procedure according to the activity of (226)Ra standard used, dependent on PSA setup, was evaluated with prepared (226)Ra solution samples and drinking water samples with assessment of measurement uncertainty variation included. Copyright © 2016 Elsevier Ltd. All rights reserved.

Energy production advantage of independent subcell connection for multijunction photovoltaics

DOE PAGES

Warmann, Emily C.; Atwater, Harry A.

2016-07-07

Increasing the number of subcells in a multijunction or "spectrum splitting" photovoltaic improves efficiency under the standard AM1.5D design spectrum, but it can lower efficiency under spectra that differ from the standard if the subcells are connected electrically in series. Using atmospheric data and the SMARTS multiple scattering and absorption model, we simulated sunny day spectra over 1 year for five locations in the United States and determined the annual energy production of spectrum splitting ensembles with 2-20 subcells connected electrically in series or independently. While electrically independent subcells have a small efficiency advantage over series-connected ensembles under the AM1.5Dmore » design spectrum, they have a pronounced energy production advantage under realistic spectra over 1 year. Simulated energy production increased with subcell number for the electrically independent ensembles, but it peaked at 8-10 subcells for those connected in series. As a result, electrically independent ensembles with 20 subcells produce up to 27% more energy annually than the series-connected 20-subcell ensemble. This energy production advantage persists when clouds are accounted for.« less

Energy production advantage of independent subcell connection for multijunction photovoltaics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warmann, Emily C.; Atwater, Harry A.

Increasing the number of subcells in a multijunction or "spectrum splitting" photovoltaic improves efficiency under the standard AM1.5D design spectrum, but it can lower efficiency under spectra that differ from the standard if the subcells are connected electrically in series. Using atmospheric data and the SMARTS multiple scattering and absorption model, we simulated sunny day spectra over 1 year for five locations in the United States and determined the annual energy production of spectrum splitting ensembles with 2-20 subcells connected electrically in series or independently. While electrically independent subcells have a small efficiency advantage over series-connected ensembles under the AM1.5Dmore » design spectrum, they have a pronounced energy production advantage under realistic spectra over 1 year. Simulated energy production increased with subcell number for the electrically independent ensembles, but it peaked at 8-10 subcells for those connected in series. As a result, electrically independent ensembles with 20 subcells produce up to 27% more energy annually than the series-connected 20-subcell ensemble. This energy production advantage persists when clouds are accounted for.« less

AMCP Partnership Forum: Enabling the Exchange of Clinical and Economic Information Pre-FDA Approval.

PubMed

2017-01-01

Current federal laws and FDA regulations have significantly restricted the sharing of clinical and health economic information on biopharmaceuticals that have yet to receive FDA approval. Over the past several years, organizations that make health care coverage decisions, including those that set copayments, premiums, and formulary placement, have expressed a need for receiving this information before approval, as long as appropriate safeguards exist to prevent this information from reaching unintended entities. Population health decision makers have indicated that waiting until FDA approval is often too late for the critical planning, budgeting, and forecasting associated with health benefit design, especially given the recent influx of high-cost medications and scrutiny for better evaluation and preparation. Recognizing that securities laws restrict the disclosure of nonpublic information and may need to be amended, permissible early dissemination would allow population health decision makers to incorporate clinical and economic information for pipeline drugs or expanded indications into financial forecasting for the following year's plan. Access to this information is needed 12-18 months before FDA approval when organizations are deciding on terms of coverage and budgetary assumptions for state health insurance rate filings, Medicare and Medicaid bids, contracts with health care purchasers, and other financial arrangements. The need for exchange of clinical economic information before FDA approval was first introduced at a previous Academy of Managed Care (AMCP) forum in March 2016, which addressed section 114 of the Food and Drug Administration Modernization Act and the communication of such information after FDA approval. To address preapproval information specifically, AMCP convened a Partnership Forum on September 13-14, 2016. This forum included a diverse group of stakeholders representing managed care, the biopharmaceutical industry, providers, patients, health economists, academia, and others. The multistakeholder group represented the key professionals and entities affected by the federal laws and FDA regulations that restrict the sharing of preapproval information and the collective credibility necessary for proposing this new communication process. Forum participants primarily focused on 6 items of discussion: (1) creating and defining new terms for how biopharmaceutical manufacturers may provide clinical and economic information 12-18 months before FDA approval; (2) defining the clinical and scientific standards that this information should meet; (3) determining which entities should have access to this information and the value to each; (4) the format and process by which this information should be disseminated; (5) developing definitions for existing terms referenced in current laws, regulations, or guidance documents that would need to be modernized to align with the identified new term; and (6) providing safeguards to prevent this information from reaching unintended entities. Forum participants selected "preapproval information exchange" (PIE) as the correct term to describe this proposed new communication process and to be inclusive of data from pivotal phase III clinical trials, pharmaco-economic data, and patient-reported outcomes, as well as other relevant items, including anticipated indications, place in therapy, and routes of administration. Stakeholders agreed that PIE should be truthful, non-misleading, and include a broad range of information to meet the needs of population health decision makers and health care technology evolution. Recipients of PIE would be limited to population health decision makers who need this information for coverage decisions. The format and process for PIE disseminated should allow for a bidirectional exchange between manufacturers and population health decision makers but should not be proscribed in legislation. Furthermore, new legislative language may be beneficial, since PIE is a novel category of information. New legislation could provide a safe harbor and clarity that PIE does not violate preapproval promotion and the Federal Food, Drug, and Cosmetic Act and its regulations. The AMCP Partnership Forum on Enabling the Exchange of Clinical and Economic Data Pre-FDA Approval and the development of this proceedings document were supported by AbbVie, Boehringer Ingelheim Pharmaceuticals, Bristol-Myers Squibb, Celgene, Intarcia Therapeutics, Eli Lilly and Company, GlaxoSmithKline, Merck, National Pharmaceutical Council, Novo Nordisk, Pfizer, Pharmaceutical Research and Manufacturers of America, Precision for Value, Sanofi, Takeda Pharmaceuticals, U.S.A., and Xcenda. All sponsors participated in the forum and in revising and approving the manuscript.

Efficient GW calculations using eigenvalue-eigenvector decomposition of the dielectric matrix

NASA Astrophysics Data System (ADS)

Nguyen, Huy-Viet; Pham, T. Anh; Rocca, Dario; Galli, Giulia

2011-03-01

During the past 25 years, the GW method has been successfully used to compute electronic quasi-particle excitation spectra of a variety of materials. It is however a computationally intensive technique, as it involves summations over occupied and empty electronic states, to evaluate both the Green function (G) and the dielectric matrix (DM) entering the expression of the screened Coulomb interaction (W). Recent developments have shown that eigenpotentials of DMs can be efficiently calculated without any explicit evaluation of empty states. In this work, we will present a computationally efficient approach to the calculations of GW spectra by combining a representation of DMs in terms of its eigenpotentials and a recently developed iterative algorithm. As a demonstration of the efficiency of the method, we will present calculations of the vertical ionization potentials of several systems. Work was funnded by SciDAC-e DE-FC02-06ER25777.

Method to generate high efficient devices which emit high quality light for illumination

DOEpatents

Krummacher, Benjamin C.; Mathai, Mathew; Choong, Vi-En; Choulis, Stelios A.

2009-06-30

An electroluminescent apparatus includes an OLED device emitting light in the blue and green spectrums, and at least one down conversion layer. The down conversion layer absorbs at least part of the green spectrum light and emits light in at least one of the orange spectra and red spectra.

Effects of ultrashort laser pulses on angular distributions of photoionization spectra.

PubMed

Ooi, C H Raymond; Ho, W L; Bandrauk, A D

2017-07-27

We study the photoelectron spectra by intense laser pulses with arbitrary time dependence and phase within the Keldysh framework. An efficient semianalytical approach using analytical transition matrix elements for hydrogenic atoms in any initial state enables efficient and accurate computation of the photoionization probability at any observation point without saddle point approximation, providing comprehensive three dimensional photoelectron angular distribution for linear and elliptical polarizations, that reveal the intricate features and provide insights on the photoionization characteristics such as angular dispersions, shift and splitting of photoelectron peaks from the tunneling or above threshold ionization(ATI) regime to non-adiabatic(intermediate) and multiphoton ionization(MPI) regimes. This facilitates the study of the effects of various laser pulse parameters on the photoelectron spectra and their angular distributions. The photoelectron peaks occur at multiples of 2ħω for linear polarization while  odd-ordered peaks are suppressed in the direction perpendicular to the electric field. Short pulses create splitting and angular dispersion where the peaks are strongly correlated to the angles. For MPI and elliptical polarization with shorter pulses the peaks split into doublets and the first peak vanishes. The carrier envelope phase(CEP) significantly affects the ATI spectra while the Stark effect shifts the spectra of intermediate regime to higher energies due to interference.

Reevaluation of secondary neutron spectra from thick targets upon heavy-ion bombardment

NASA Astrophysics Data System (ADS)

Satoh, D.; Kurosawa, T.; Sato, T.; Endo, A.; Takada, M.; Iwase, H.; Nakamura, T.; Niita, K.

2007-12-01

Previously published data of secondary neutron spectra from thick targets of C, Al, Cu and Pb bombarded with heavy ions from He to Xe are revised by using a new set of neutron-detection efficiency values for a liquid organic scintillator calculated with SCINFUL-QMD. Additional data have been measured for bombardment of C target by 400-MeV/nucleon C ions and 800-MeV/nucleon Si ions. The set of spectra are compared with the calculation results using a Monte-Carlo heavy-ion transport code, PHITS. It was found that PHITS is able to reproduce the secondary neutron spectra in a wide neutron-energy regime.

Cis- and trans-perfluorodecalin: Infrared spectra, radiative efficiency and global warming potential

NASA Astrophysics Data System (ADS)

Le Bris, Karine; DeZeeuw, Jasmine; Godin, Paul J.; Strong, Kimberly

2017-12-01

Perfluorodecalin (PFD) is a molecule used in various medical applications for its capacity to dissolve gases. This potent greenhouse gas was detected for the first time in the atmosphere in 2005. We present infrared absorption cross-section spectra of a pure vapour of cis- and trans-perfluorodecalin at a resolution of 0.1 cm-1. Measurements were performed in the 560-3000 cm-1 spectral range using Fourier transform spectroscopy. The spectra have been compared with previous experimental data and theoretical calculations by density functional theory. The new experimental absorption cross-sections have been used to calculate a lifetime-corrected radiative efficiency at 300 K of 0.62 W m-2 ppb-1 and 0.57 W.m-2.ppb-1 for the cis and trans isomers respectively. This leads to a 100-year time horizon global warming potential of 8030 for cis-PFD and 7440 for trans-PFD.

Act Now to Transform School Systems. 2011 PIE Network Summit Policy Briefs

ERIC Educational Resources Information Center

Miles, Karen Hawley; Baroody, Karen

2011-01-01

The U.S.'s educational system is at a crossroads. Preparing every student for college and careers in the information age requires that school districts invest more and differently in teaching effectiveness, time, individual attention, and information systems. But even before a decline in revenue, district leaders face automatic increases in…

Making Curriculum Pop: Developing Literacies in All Content Areas

ERIC Educational Resources Information Center

Goble, Pam; Goble, Ryan R.

2016-01-01

From comics to cathedrals, pie charts to power ballads, fashion to Facebook . . . students need help navigating today's mediarich world. And educators need help teaching today's new media literacy. To be "literate" now means being able to read, write, listen, speak, view, and represent across all media--including both print and nonprint…

The Future (If Any) of IT

ERIC Educational Resources Information Center

Stuart, Lynn, M.

2004-01-01

IT organizations are still here. Why? This question is not about survival of IT as a whole but rather about survival of central IT organizations and their share of the institutional IT pie. IT as a whole will certainly survive, perhaps at even greater institutional overall cost. Decentralization only stimulates appetites for more. And woe to the…

Apple Stack Cake for Dessert: Appalachian Regional Foods

ERIC Educational Resources Information Center

Shortridge, Barbara G.

2005-01-01

How is the culture of Appalachia conveyed through its foods? Local experts in Appalachian counties were asked to create a hypothetical menu for a meal that was representative of their home region. Fried chicken and ham were the preferred main dishes and dessert selections focused on apple pie and peach or blackberry cobbler. Virtually everyone…

The Alpha and Omega Syndrome: Is Intra-District Funding the next Ripeness Factor?

ERIC Educational Resources Information Center

Owings, William A.; Kaplan, Leslie S.

2010-01-01

Fiscal disparities within school districts may be the next area "ripe" for litigation. Equity and adequacy litigation have largely focused on between-district fiscal disparities. Research suggests that within-district disparities may be as unfair to high poverty schools. When the school funding pie is not growing, remedying…

Group Contagion: The Mailbox Melee

ERIC Educational Resources Information Center

Morse, William C.

2010-01-01

In a group situation, something goes wrong but no individual feels personal responsibility. This is called the "pie" phenomenon because everybody has a piece of the action, but all believe they are innocent. Each contributes to contagion and chaos but all say, "We didn't do nothing." In this article, the author, a pioneer in work with troubled…

Translations on North Korea, Number 551, KULLOJA, Number 6, 1977

DTIC Science & Technology

1977-09-16

with the ever higher glory of a victor who has occu- pied the towering heights of the Six-Year Plan they are brilliantly fulfilling this year’s tasks...with panache staking the honor of Chuche Korea, Hero Korea. An important question arising in further strengthening national defense might in

Reportable STDs in Young People 15-24 Years of Age, by State

MedlinePlus

... STD 101 in a Box Home Script for Sex in the City Video STD Clinical Slides STD Clinical Slides STD Picture ... include: line graphs by year; pie charts for sex; bar charts by state and country; bar charts for age, race/ethnicity, and transmission ... Quicktime file RealPlayer file Text file ...

Sharing Smaller Pies.

ERIC Educational Resources Information Center

Bender, Tom

This paper details the unfavorable predicament of the United States as a consequence of using much of its own non-renewable material and energy resources. As a consequence, the United States will soon be subject to the political and economic conditions imposed upon it by other nations. The United States must begin to implement adjustments to the…

Dealing with Institutional Racism on Campus: Initiating Difficult Dialogues and Social Justice Advocacy Interventions

ERIC Educational Resources Information Center

D'Andrea, Michael; Daniels, Judy

2007-01-01

The authors describe social justice advocacy interventions to initiate difficult discussions at the university where they are employed. They emphasize the need to foster difficult dialogues about the problem of institutional racism among students, faculty members, and administrators where they work. The Privileged Identity Exploration (PIE) model…

Lessons to be learned: a case study approach. Unseasonal severe poisoning of two adults by deadly nightside (Atropa belladonna).

PubMed

Southgate, H J; Egerton, M; Dauncey, E A

2000-06-01

Unseasonal, mid-winter, severe poisoning by deadly nightshade is reported in two adults who simultaneously ate from a pie made of frozen deadly nightshade berries, mistaken at the time of picking for bilberries. Atropine levels are reported in the urine. Physostigmine treatment was ineffective.

Massive and Open

ERIC Educational Resources Information Center

Fasimpaur, Karen

2013-01-01

MOOCs--massive open online courses--are all the rage these days, with hundreds of thousands of participants signing up and investors plunking down millions to get a piece of the pie. Why is there so much excitement about this new disruptive form of online learning, and how does this model apply to professional learning for teachers? Traditional…

Getting a Piece of the Pie: R&D at the Apple Library.

ERIC Educational Resources Information Center

Ertel, Monica

1990-01-01

The Apple Library (the library at Apple Computer, Inc.) currently reports to the research and development arm of the company, a relationship that has been mutually advantageous. The library has been involved in research through a library users group, a grant program, and a laboratory within the library. (MES)

Metacoder: An R package for visualization and manipulation of community taxonomic diversity data

USDA-ARS?s Scientific Manuscript database

Community composition data, the type generated by an increasing number of metabarcoding studies, is often graphed as stacked bar charts or pie graphs. These graph types do not convey the hierarchical structure of taxonomic classifications and are limited by the use of color for categories. As an alt...

Baseline Acidity of Ancient Precipitation from the South Pole,

DTIC Science & Technology

1984-06-01

is to use samples of polar snow and ice that Most studies of acid precipitation have used were deposited before the industrial revolution relatively...saturated and C0 2-free South the onset of the industrial revolution . Older sam- Pole ice core samples spanning the last 2000 years pies were selected at 20-m

Motherhood, Apple Pie, and Differentiated Instruction

ERIC Educational Resources Information Center

VanSciver, James H.

2005-01-01

A good Little League baseball coach will analyze a pitcher's performance and develop an individual prescription based on that analysis. Just as all pitchers do not receive the same remedies from high-quality coaches, the author believes, neither should all students. No Child Left Behind (NCLB) stands as the imposing batter to many teachers and…

Innovation, Motherhood, and Apple Pie. Brown Center Letters on Education

ERIC Educational Resources Information Center

Whitehurst, Grover

2009-01-01

The American Recovery and Reinvestment Act of 2009 authorized the Secretary of Education to establish a $650 million Innovation Fund to expand the work of schools that have made gains in closing achievement gaps. With growing discussion and considerable money heading in the direction of innovation, Grover "Russ" Whitehurst provides recommendations…

We, the Asian and Pacific Islander Americans.

ERIC Educational Resources Information Center

Johnson, Dwight L.; And Others

Demographic data are presented about the people who have immigrated to the United States from Asia and the Pacific Islands. Twelve figures (pie charts, bar graphs, and maps), and eight tables provide detailed, statistical information on such things as (1) distribution of Asians and Pacific Islanders in the United States, (2) states with the…

Field Portable Methods for Rapid Water Quality Analysis

DTIC Science & Technology

1996-10-01

a pie-shaped segment of the rolled cylinder, also stored in a sterile flask. Several membrane layers were pulled away, and a scraping was removed for...For example, the H. pylori urease A gene can be used, and thefla A gene can be used for the campylobacter species. 12 2. Implement microwave technology

Reimagining the Color Wheel

ERIC Educational Resources Information Center

Snyder, Jennifer

2011-01-01

Color wheels are a traditional project for many teachers. The author has used them in art appreciation classes for many years, but one problem she found when her pre-service art education students created colored wheels was that they were boring: simple circles, with pie-shaped pieces, which students either painted or colored in. This article…

Professional Notes: Reaching All Students via Technology

ERIC Educational Resources Information Center

Nelson, Deborah

2013-01-01

Music teachers are often the Pied Pipers of their schools, attracting the interest of students by the nature of the subject they teach. Their students who excel are often the best and brightest, since music reading and music production demand higher-level thinking skills, motor ability, and in the case of ensemble performance, social skills. As…

Huzzah Means Hooray: Activities from the Days of Damsels, Jesters, and Blackbirds in a Pie. First Edition.

ERIC Educational Resources Information Center

Carlson, Laurie

Written for juveniles, this book presents information and activities aimed at increasing student understanding of the life experiences of Europeans during the Middle Ages. Student activities are organized by the following categories: (1) "Medieval--What's That?" presents background information; (2) "Lets Dress Up!" examines…

Energy Blocks--A Physical Model for Teaching Energy Concepts

ERIC Educational Resources Information Center

Hertting, Scott

2016-01-01

Most physics educators would agree that energy is a very useful, albeit abstract topic. It is therefore important to use various methods to help the student internalize the concept of energy itself and its related ideas. These methods include using representations such as energy bar graphs, energy pie charts, or energy tracking diagrams.…

Comfort Foods and Mood

DTIC Science & Technology

2008-07-01

others much larger - have developed into mini-American towns.On some bases, troops fresh off of a patrol can stroll in for a sandwich at a makeshift... Subway , grab a pie at Pizza Hut or get a Whopper from Burger King. QuickTime™ and a decompressor are needed to see this picture. Even in the chow

Integration of wireless sensor networks into automatic irrigation scheduling of a center pivot

USDA-ARS?s Scientific Manuscript database

A six-span center pivot system was used as a platform for testing two wireless sensor networks (WSN) of infrared thermometers. The cropped field was a semi-circle, divided into six pie shaped sections of which three were irrigated manually and three were irrigated automatically based on the time tem...

The impact of a child passenger restraint law and a public information and education program on child passenger safety in Tennessee

DOT National Transportation Integrated Search

1980-10-01

This report provides an analysis of the impact of child passenger protection legislation and a public information and education (PI&E) program on child passenger safety in Tennessee. This study is unique in that Tennessee was the first state to pass ...

The Development of the Graphics-Decoding Proficiency Instrument

ERIC Educational Resources Information Center

Lowrie, Tom; Diezmann, Carmel M.; Kay, Russell

2011-01-01

The graphics-decoding proficiency (G-DP) instrument was developed as a screening test for the purpose of measuring students' (aged 8-11 years) capacity to solve graphics-based mathematics tasks. These tasks include number lines, column graphs, maps and pie charts. The instrument was developed within a theoretical framework which highlights the…

Intermediate cultural practices

Treesearch

W. Robert Dinneen

1977-01-01

What are these interesting sounding things? Are they theory, are they pie in the sky, fantasies of desk foresters - or are they the real McCoy - something the landowner needs if he is going to make his woodlands pay a return on his investment. To list briefly, shall we say they are pre-commercial treatments, marginal commercial treatments, commercial thinnings,...

Prophesy or Pie in the Sky? Canadian Forces Transformation vs the Future Operating Environment

DTIC Science & Technology

2006-03-15

Canadian Army Colonel Peter Zielinski Project Adviser This SRP is submitted in partial fulfillment of the requirements of the Master of Strategic...Ibid. 32 Lieutenant-Colonel Dave Galea, “A Light Force Capability for the Army,” in Canadian Army Journal, 8, (Kingston, ON, Her Majesty the Queen in

Teaching Statistics: Creating an Intersection for Intra and Interdisciplinarity

ERIC Educational Resources Information Center

Savard, Annie; Manuel, Dominic

2016-01-01

Statistics is taught in mathematics courses in all school levels. We suggest that using rich tasks in statistics can develop statistical reasoning and create both intra and interdisciplinary links in students. In this paper, we present three case studies where middle school mathematics teachers used different tasks in lessons on pie charts. We…

The why of practice: utilizing PIE to analyze social work practice in Australian hospitals.

PubMed

Nilsson, David; Joubert, Lynette; Holland, Lucy; Posenelli, Sonia

2013-01-01

This research used a collaborative approach to gain a comprehensive, quantitative understanding of the breadth and depth of the social work role in health care. Data was collected from individual interviews with all employed hospital social workers (N = 120) across five Melbourne, Australia health networks about their most recently completed case. This data was coded using a revised version of the Karls and Wandrei (1994) Person-in-Environment (PIE) tool to retrospectively analyze the reasons for social work involvement over the course of the case. The findings demonstrate that the hospital social work role is multidimensional across a number of domains but centers predominantly on assisting clients and their significant others with issues of altered social roles and functioning; particularly in relation to role responsibility, dependency, and managing associated role-change losses. The findings of this study will assist hospital social workers, managers, and academics to better describe and effectively undertake this complex work. These findings will also assist in the development of professional training and education to up-skill social workers who operate within this complex setting.

Neutron Focusing Mirrors for Neutron Radiography of Irradiated Nuclear Fuel at Idaho National Laboratory

NASA Astrophysics Data System (ADS)

Rai, Durgesh K.; Wu, Huarui; Abir, Muhammad; Giglio, Jeffrey; Khaykovich, Boris

Post irradiation examination (PIE) of samples irradiated in nuclear reactors is a challenging but necessary task for the development on novel nuclear power reactors. Idaho National Laboratory (INL) has neutron radiography capabilities, which are especially useful for the PIE of irradiated nuclear fuel. These capabilities are limited due to the extremely high gamma-ray radiation from the irradiated fuel, which precludes the use of standard digital detectors, in turn limiting the ability to do tomography and driving the cost of the measurements. In addition, the small 250 kW Neutron Radiography Reactor (NRAD) provides a relatively weak neutron flux, which leads to low signal-to-noise ratio. In this work, we develop neutron focusing optics suitable for the installation at NRAD. The optics would separate the sample and the detector, potentially allowing for the use of digital radiography detectors, and would provide significant intensity enhancement as well. The optics consist of several coaxial nested Wolter mirrors and is suited for polychromatic thermal neutron radiation. Laboratory Directed Research and Development program of Idaho National Laboratory.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yim, J. S.; Tahk, Y. W.; Oh, J. Y.

In order to cope with global shortage of Mo-99 supplies and with growing demand of neutron transmutation doping, KJRR construction plan has been launched since April 2012 to provide self-sufficiency of domestic RI demand, and to extend Si doping capacity for power device market growth. Through comprehensive surveillance of the fuels in-reactor behavior, KAERI has selected the fuel meat of U-7%Mo dispersion in an aluminum matrix with 5wt%Si for the KJRR fuel. As part of the efforts for fuel licensing and qualification of the KJRR fuel, an LTA irradiation test at the ATR started from November 2015 was successfully completedmore » by reaching at 219 EFPD in the end of February 2017. Together with the results of HAMP-1 already completed irradiation and PIE, the successful irradiation of the LTA also demonstrates the fuel integrity under more rigorous conditions than the KJRR operation conditions. This paper updates the current status of the KJRR U7Mo (8 g-U/cm3) LTA irradiation and PIE plan up to date as of February 2017.« less

Application of X-Ray Computer Tomography for Observing the Central Void Formations and the Fuel Pin Deformations of Irradiated FBR Fuel Assemblies

NASA Astrophysics Data System (ADS)

Katsuyama, Kozo; Nagamine, Tsuyoshi; Furuya, Hirotaka

2010-10-01

In order to observe the structural change in the interior of irradiated fuel assemblies, a non-destructive post-irradiation examination (PIE) technique using X-ray computer tomography (X-ray CT) was developed. This X-ray CT technique was applied to observe the central void formations and fuel pin deformations of fuel assemblies which had been irradiated at high linear heat rating. The central void sizes in all fuel pins were measured on five cross sections of the core fuel column as a parameter for evaluating fuel thermal performance. In addition, the fuel pin deformations were analyzed from X-ray CT images obtained along the axial direction of a fuel assembly at the same separation interval. A dependence of void size on the linear heat rating was seen in the fuel assembly irradiated at high linear heat rating. In addition, significant undulations of the fuel pin were observed along the axial direction, coinciding with the wrapping wire pitch in the core fuel column. Application of the developed technique should provide enhanced resolution of measurements and simplify fuel PIEs.

Deforestation in Bolivia

NASA Technical Reports Server (NTRS)

2002-01-01

This image from Landsat7, acquired on August 1, 2000, shows the new agricultural settlements east of Santa Cruz de la Sierra, Bolivia in an area of tropical dry forest. Since the mid-1980s, this region has been rapidly deforested as a result of the resettlement of people from the Altiplano (the Andean high plains) and a large agricultural development effort, called the Tierras Baja project. The pie or radial patterned fields (left) are part of the San Javier resettlement scheme. At the center of each unit is a small community including a church, bar/cafe, school, and soccer field-the essentials of life in rural Bolivia. The rectilinear, light-colored areas (right) are fields of soybeans cultivated for export that are mostly funded by foreign loans. The dark strips running through these fields are wind breaks. These are advantageous because the soils in this area are fine and prone to wind erosion. Large version of pie-shaped fields (420 kb) Large version of linear fields (360 kb) Landsat image courtesy USGS EROS Data Center and Landsat7 science team. Photographs courtesy Compton Tucker, NASA GSFC.

Putting Safety in the Software

NASA Technical Reports Server (NTRS)

Wetherholt, Martha S.; Berens, Kalynnda M.; Hardy, Sandra (Technical Monitor)

2001-01-01

Software is a vital component of nearly every piece of modern technology. It is not a 'sub-system', able to be separated out from the system as a whole, but a 'co-system' that controls, manipulates, or interacts with the hardware and with the end user. Software has its fingers into all the pieces of the pie. If that 'pie', the system, can lead to injury, death, loss of major equipment, or impact your business bottom line, then software safety becomes vitally important. Learning to think about software from a safety perspective is the focus of this paper. We want you to think of software as part of the safety critical system, a major part. This requires 'system thinking' - being able to grasp the whole picture. Software's contribution to modern technology is both good and potentially bad. Software allows more complex and useful devices to be built. It can also contribute to plane crashes and power outages. We want you to see software in a whole new light, see it as a contributor to system hazards, and also as a possible fix or mitigation to some of those hazards.

Thioflavin T as an efficient fluorescence sensor for selective recognition of RNA G-quadruplexes

NASA Astrophysics Data System (ADS)

Xu, Shujuan; Li, Qian; Xiang, Junfeng; Yang, Qianfan; Sun, Hongxia; Guan, Aijiao; Wang, Lixia; Liu, Yan; Yu, Lijia; Shi, Yunhua; Chen, Hongbo; Tang, Yalin

2016-04-01

RNA G-quadruplexes (G4s) play important roles in translational regulation, mRNA processing events and gene expression. Therefore, a fluorescent probe that is capable of efficiently recognizing RNA G-quadruplex structures among other RNA forms is highly desirable. In this study, a water-soluble fluorogenic dye (i.e., Thioflavin T (ThT)) was employed to recognize RNA G-quadruplex structures using UV-Vis absorption spectra, fluorescence spectra and emission lifetime experiments. By stacking on the G-tetrad, the ThT probe exhibited highly specific recognition of RNA G-quadruplex structures with striking fluorescence enhancement compared with other RNA forms. The specific binding demonstrates that ThT is an efficient fluorescence sensor that can distinguish G4 and non-G4 RNA structures.

Numerical Study of the Generation of Linear Energy Transfer Spectra for Space Radiation Applications

NASA Technical Reports Server (NTRS)

Badavi, Francis F.; Wilson, John W.; Hunter, Abigail

2005-01-01

In analyzing charged particle spectra in space due to galactic cosmic rays (GCR) and solar particle events (SPE), the conversion of particle energy spectra into linear energy transfer (LET) distributions is a convenient guide in assessing biologically significant components of these spectra. The mapping of LET to energy is triple valued and can be defined only on open energy subintervals where the derivative of LET with respect to energy is not zero. Presented here is a well-defined numerical procedure which allows for the generation of LET spectra on the open energy subintervals that are integrable in spite of their singular nature. The efficiency and accuracy of the numerical procedures is demonstrated by providing examples of computed differential and integral LET spectra and their equilibrium components for historically large SPEs and 1977 solar minimum GCR environments. Due to the biological significance of tissue, all simulations are done with tissue as the target material.

Natal habitat imprinting counteracts the diversifying effects of phenotype-dependent dispersal in a spatially structured population.

PubMed

Camacho, Carlos; Canal, David; Potti, Jaime

2016-08-08

Habitat selection may have profound evolutionary consequences, but they strongly depend on the underlying preference mechanism, including genetically-determined, natal habitat and phenotype-dependent preferences. It is known that different mechanisms may operate at the same time, yet their relative contribution to population differentiation remains largely unexplored empirically mainly because of the difficulty of finding suitable study systems. Here, we investigate the role of early experience and genetic background in determining the outcome of settlement by pied flycatchers (Ficedula hypoleuca) breeding in two habitat patches between which dispersal and subsequent reproductive performance is influenced by phenotype (body size). For this, we conducted a cross-fostering experiment in a two-patch system: an oakwood and a conifer plantation separated by only 1 km. Experimental birds mostly returned to breed in the forest patch where they were raised, whether it was that of their genetic or their foster parents, indicating that decisions on where to settle are determined by individuals' experience in their natal site, rather than by their genetic background. Nevertheless, nearly a third (27.6 %) moved away from the rearing habitat and, as previously observed in unmanipulated individuals, dispersal between habitats was phenotype-dependent. Pied flycatchers breeding in the oak and the pine forests are differentiated by body size, and analyses of genetic variation at microsatellite loci now provide evidence of subtle genetic differentiation between the two populations. This suggests that phenotype-dependent dispersal may contribute to population structure despite the short distance and widespread exchange of birds between the study plots. Taken together, the current and previous findings that pied flycatchers do not always settle in the habitat to which they are best suited suggest that their strong tendency to return to the natal patch regardless of their body size might lead to maladaptive settlement decisions and thus constrain the potential of phenotype-dependent dispersal to promote microgeographic adaptation.

Demographic Divergence History of Pied Flycatcher and Collared Flycatcher Inferred from Whole-Genome Re-sequencing Data

PubMed Central

Nadachowska-Brzyska, Krystyna; Burri, Reto; Olason, Pall I.; Kawakami, Takeshi; Smeds, Linnéa; Ellegren, Hans

2013-01-01

Profound knowledge of demographic history is a prerequisite for the understanding and inference of processes involved in the evolution of population differentiation and speciation. Together with new coalescent-based methods, the recent availability of genome-wide data enables investigation of differentiation and divergence processes at unprecedented depth. We combined two powerful approaches, full Approximate Bayesian Computation analysis (ABC) and pairwise sequentially Markovian coalescent modeling (PSMC), to reconstruct the demographic history of the split between two avian speciation model species, the pied flycatcher and collared flycatcher. Using whole-genome re-sequencing data from 20 individuals, we investigated 15 demographic models including different levels and patterns of gene flow, and changes in effective population size over time. ABC provided high support for recent (mode 0.3 my, range <0.7 my) species divergence, declines in effective population size of both species since their initial divergence, and unidirectional recent gene flow from pied flycatcher into collared flycatcher. The estimated divergence time and population size changes, supported by PSMC results, suggest that the ancestral species persisted through one of the glacial periods of middle Pleistocene and then split into two large populations that first increased in size before going through severe bottlenecks and expanding into their current ranges. Secondary contact appears to have been established after the last glacial maximum. The severity of the bottlenecks at the last glacial maximum is indicated by the discrepancy between current effective population sizes (20,000–80,000) and census sizes (5–50 million birds) of the two species. The recent divergence time challenges the supposition that avian speciation is a relatively slow process with extended times for intrinsic postzygotic reproductive barriers to evolve. Our study emphasizes the importance of using genome-wide data to unravel tangled demographic histories. Moreover, it constitutes one of the first examples of the inference of divergence history from genome-wide data in non-model species. PMID:24244198

Demographic divergence history of pied flycatcher and collared flycatcher inferred from whole-genome re-sequencing data.

PubMed

Nadachowska-Brzyska, Krystyna; Burri, Reto; Olason, Pall I; Kawakami, Takeshi; Smeds, Linnéa; Ellegren, Hans

2013-11-01

Profound knowledge of demographic history is a prerequisite for the understanding and inference of processes involved in the evolution of population differentiation and speciation. Together with new coalescent-based methods, the recent availability of genome-wide data enables investigation of differentiation and divergence processes at unprecedented depth. We combined two powerful approaches, full Approximate Bayesian Computation analysis (ABC) and pairwise sequentially Markovian coalescent modeling (PSMC), to reconstruct the demographic history of the split between two avian speciation model species, the pied flycatcher and collared flycatcher. Using whole-genome re-sequencing data from 20 individuals, we investigated 15 demographic models including different levels and patterns of gene flow, and changes in effective population size over time. ABC provided high support for recent (mode 0.3 my, range <0.7 my) species divergence, declines in effective population size of both species since their initial divergence, and unidirectional recent gene flow from pied flycatcher into collared flycatcher. The estimated divergence time and population size changes, supported by PSMC results, suggest that the ancestral species persisted through one of the glacial periods of middle Pleistocene and then split into two large populations that first increased in size before going through severe bottlenecks and expanding into their current ranges. Secondary contact appears to have been established after the last glacial maximum. The severity of the bottlenecks at the last glacial maximum is indicated by the discrepancy between current effective population sizes (20,000-80,000) and census sizes (5-50 million birds) of the two species. The recent divergence time challenges the supposition that avian speciation is a relatively slow process with extended times for intrinsic postzygotic reproductive barriers to evolve. Our study emphasizes the importance of using genome-wide data to unravel tangled demographic histories. Moreover, it constitutes one of the first examples of the inference of divergence history from genome-wide data in non-model species.

Upgrade to MODFLOW-GUI; addition of MODPATH, ZONEBDGT, and additional MODFLOW packages to the U.S. Geological Survey MODFLOW-96 Graphical-User Interface

USGS Publications Warehouse

Winston, R.B.

1999-01-01

This report describes enhancements to a Graphical-User Interface (GUI) for MODFLOW-96, the U.S. Geological Survey (USGS) modular, three-dimensional, finitedifference ground-water flow model, and MOC3D, the USGS three-dimensional, method-ofcharacteristics solute-transport model. The GUI is a plug-in extension (PIE) for the commercial program Argus ONEe. The GUI has been modified to support MODPATH (a particle tracking post-processing package for MODFLOW), ZONEBDGT (a computer program for calculating subregional water budgets), and the Stream, Horizontal-Flow Barrier, and Flow and Head Boundary packages in MODFLOW. Context-sensitive help has been added to make the GUI easier to use and to understand. In large part, the help consists of quotations from the relevant sections of this report and its predecessors. The revised interface includes automatic creation of geospatial information layers required for the added programs and packages, and menus and dialog boxes for input of parameters for simulation control. The GUI creates formatted ASCII files that can be read by MODFLOW-96, MOC3D, MODPATH, and ZONEBDGT. All four programs can be executed within the Argus ONEe application (Argus Interware, Inc., 1997). Spatial results of MODFLOW-96, MOC3D, and MODPATH can be visualized within Argus ONEe. Results from ZONEBDGT can be visualized in an independent program that can also be used to view budget data from MODFLOW, MOC3D, and SUTRA. Another independent program extracts hydrographs of head or drawdown at individual cells from formatted MODFLOW head and drawdown files. A web-based tutorial on the use of MODFLOW with Argus ONE has also been updated. The internal structure of the GUI has been modified to make it possible for advanced users to easily customize the GUI. Two additional, independent PIE?s were developed to allow users to edit the positions of nodes and to facilitate exporting the grid geometry to external programs.

A watershed-based adaptive knowledge system for developing ecosystem stakeholder partnerships

NASA Astrophysics Data System (ADS)

Lin, Hebin; Thornton, Jeffrey A.; Shadrin, Nickolai

2015-11-01

This study proposes a Watershed-based Adaptive Knowledge System (WAKES) to consistently coordinate multiple stakeholders in developing sustainable partnerships for ecosystem management. WAKES is extended from the institutional mechanism of Payments for Improving Ecosystem Services at the Watershed-scale (PIES-W). PIES-W is designed relating to the governance of ecosystem services fl ows focused on a lake as a resource stock connecting its infl owing and outfl owing rivers within its watershed. It explicitly realizes the values of conservation services provided by private land managers and incorporates their activities into the public organizing framework for ecosystem management. It implicitly extends the "upstream-to-downstream" organizing perspective to a broader vision of viewing the ecosystems as comprised of both "watershed landscapes" and "marine landscapes". Extended from PIES-W, WAKES specifies two corresponding feedback: Framework I and II. Framework I is a relationship matrix comprised of three input-output structures of primary governance factors intersecting three subsystems of a watershed with regard to ecosystem services and human stakeholders. Framework II is the Stakeholder-and-Information structure channeling five types of information among four stakeholder groups in order to enable the feedbacks mechanism of Framework I. WAKES identifies the rationales behind three fundamental information transformations, illustrated with the Transboundary Diagnostic Analysis and the Strategic Action Program of the Bermejo River Binational Basin. These include (1) translating scientific knowledge into public information within the Function-and-Service structure corresponding to the ecological subsystem, (2) incorporating public perceptions into political will within the Service- and- Value structure corresponding to the economic subsystem, and (3) integrating scientific knowledge, public perceptions and political will into management options within the Value-and-Stakeholder structure corresponding to the social subsystem. This study seeks to share a vision of social adaptation for a global sustainable future through developing a network to adopt contributions from and forming partnerships among all ecosystem stakeholders.

Efficient implementation of core-excitation Bethe-Salpeter equation calculations

NASA Astrophysics Data System (ADS)

Gilmore, K.; Vinson, John; Shirley, E. L.; Prendergast, D.; Pemmaraju, C. D.; Kas, J. J.; Vila, F. D.; Rehr, J. J.

2015-12-01

We present an efficient implementation of the Bethe-Salpeter equation (BSE) method for obtaining core-level spectra including X-ray absorption (XAS), X-ray emission (XES), and both resonant and non-resonant inelastic X-ray scattering spectra (N/RIXS). Calculations are based on density functional theory (DFT) electronic structures generated either by ABINIT or QuantumESPRESSO, both plane-wave basis, pseudopotential codes. This electronic structure is improved through the inclusion of a GW self energy. The projector augmented wave technique is used to evaluate transition matrix elements between core-level and band states. Final two-particle scattering states are obtained with the NIST core-level BSE solver (NBSE). We have previously reported this implementation, which we refer to as OCEAN (Obtaining Core Excitations from Ab initio electronic structure and NBSE) (Vinson et al., 2011). Here, we present additional efficiencies that enable us to evaluate spectra for systems ten times larger than previously possible; containing up to a few thousand electrons. These improvements include the implementation of optimal basis functions that reduce the cost of the initial DFT calculations, more complete parallelization of the screening calculation and of the action of the BSE Hamiltonian, and various memory reductions. Scaling is demonstrated on supercells of SrTiO3 and example spectra for the organic light emitting molecule Tris-(8-hydroxyquinoline)aluminum (Alq3) are presented. The ability to perform large-scale spectral calculations is particularly advantageous for investigating dilute or non-periodic systems such as doped materials, amorphous systems, or complex nano-structures.

Growth, spectroscopy and continuous-wave laser performance of Nd3+:LiLu0.65Y0.35F4 crystal

NASA Astrophysics Data System (ADS)

Demesh, M. P.; Kurilchik, S. V.; Gusakova, N. V.; Yasukevich, A. S.; Kisel, V. E.; Nizamutdinov, A. S.; Marisov, M. M.; Aglyamov, R. D.; Korableva, S. L.; Naumov, A. K.; Semashko, V. V.; Kuleshov, N. V.

2018-04-01

A mixed fluoride crystal of LiLu0.65Y0.35F4 doped with Nd3+ ions was grown by the Bridgman-Stockbarger method. Polarized absorption and luminescence spectra as well as luminescence lifetime were measured at room temperature. Emission probabilities, branching ratios and radiative lifetime were studied within the Judd-Ofelt theory and the emission cross section spectra were calculated. Efficient continuous wave laser operation was demonstrated with the crystal. A maximum output power of 7.7 W and slope efficiency of 60% were achieved at 1047 nm for the TEM00 mode.

Realizing Rec. 2020 color gamut with quantum dot displays.

PubMed

Zhu, Ruidong; Luo, Zhenyue; Chen, Haiwei; Dong, Yajie; Wu, Shin-Tson

2015-09-07

We analyze how to realize Rec. 2020 wide color gamut with quantum dots. For photoluminescence, our simulation indicates that we are able to achieve over 97% of the Rec. 2020 standard with quantum dots by optimizing the emission spectra and redesigning the color filters. For electroluminescence, by optimizing the emission spectra of quantum dots is adequate to render over 97% of the Rec. 2020 standard. We also analyze the efficiency and angular performance of these devices, and then compare results with LCDs using green and red phosphors-based LED backlight. Our results indicate that quantum dot display is an outstanding candidate for achieving wide color gamut and high optical efficiency.

Dissociative photoionization of isoprene: experiments and calculations.

PubMed

Liu, Xianyun; Zhang, Weijun; Wang, Zhenya; Huang, Mingqiang; Yang, Xibin; Tao, Ling; Sun, Yue; Xu, Yuntao; Shan, Xiaobin; Liu, Fuyi; Sheng, Liusi

2009-03-01

Vacuum ultraviolet (VUV) dissociative photoionization of isoprene in the energy region 8.5-18 eV was investigated with photoionization mass spectroscopy (PIMS) using synchrotron radiation (SR). The ionization energy (IE) of isoprene as well as the appearance energies (AEs) of its fragment ions C(5)H(7) (+), C(5)H(5) (+), C(4)H(5) (+), C(3)H(6) (+), C(3)H(5) (+), C(3)H(4) (+), C(3)H(3) (+) and C(2)H(3) (+) were determined with photoionization efficiency (PIE) curves. The dissociation energies of some possible dissociation channels to produce those fragment ions were also determined experimentally. The total energies of C(5)H(8) and its main fragments were calculated using the Gaussian 03 program and the Gaussian-2 method. The IE of C(5)H(8), the AEs for its fragment ions, and the dissociation energies to produce them were predicted using the high-accuracy energy model. According to our results, the experimental dissociation energies were in reasonable agreement with the calculated values of the proposed photodissociation channels of C(5)H(8). Copyright (c) 2009 John Wiley & Sons, Ltd.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenberg, Michael; Jonlin, Duane; Nadel, Steven

Today’s building energy codes focus on prescriptive requirements for features of buildings that are directly controlled by the design and construction teams and verifiable by municipal inspectors. Although these code requirements have had a significant impact, they fail to influence a large slice of the building energy use pie – including not only miscellaneous plug loads, cooking equipment and commercial/industrial processes, but the maintenance and optimization of the code-mandated systems as well. Currently, code compliance is verified only through the end of construction, and there are no limits or consequences for the actual energy use in an occupied building. Inmore » the future, our suite of energy regulations will likely expand to include building efficiency, energy use or carbon emission budgets over their full life cycle. Intelligent building systems, extensive renewable energy, and a transition from fossil fuel to electric heating systems will likely be required to meet ultra-low-energy targets. This paper lays out the authors’ perspectives on how buildings may evolve over the course of the 21st century and the roles that codes and regulations will play in shaping those buildings of the future.« less

Simplified expressions that incorporate finite pulse effects into coherent two-dimensional optical spectra.

PubMed

Do, Thanh Nhut; Gelin, Maxim F; Tan, Howe-Siang

2017-10-14

We derive general expressions that incorporate finite pulse envelope effects into a coherent two-dimensional optical spectroscopy (2DOS) technique. These expressions are simpler and less computationally intensive than the conventional triple integral calculations needed to simulate 2DOS spectra. The simplified expressions involving multiplications of arbitrary pulse spectra with 2D spectral response function are shown to be exactly equal to the conventional triple integral calculations of 2DOS spectra if the 2D spectral response functions do not vary with population time. With minor modifications, they are also accurate for 2D spectral response functions with quantum beats and exponential decay during population time. These conditions cover a broad range of experimental 2DOS spectra. For certain analytically defined pulse spectra, we also derived expressions of 2D spectra for arbitrary population time dependent 2DOS spectral response functions. Having simpler and more efficient methods to calculate experimentally relevant 2DOS spectra with finite pulse effect considered will be important in the simulation and understanding of the complex systems routinely being studied by using 2DOS.

Hyper-spectral imaging in scanning-confocal-fluorescence microscopy using a novel broadband diffractive optic

NASA Astrophysics Data System (ADS)

Wang, Peng; Ebeling, Carl G.; Gerton, Jordan; Menon, Rajesh

In this paper, we demonstrate hyper-spectral imaging of fluorescent microspheres in a scanning-confocal-fluorescence microscope by spatially dispersing the spectra using a novel broadband diffractive optic, and applying a nonlinear optimization technique to extract the full-incident spectra. This broadband diffractive optic has a designed optical efficiency of over 90% across the entire visible spectrum. We used this technique to create two-color images of two fluorophores and also extracted their emission spectra with good fidelity. This method can be extended to image both spatially and spectrally overlapping fluorescent samples. Full control in the number of emission spectra and the feasibility of enhanced imaging speed are demonstrated as well.

ASERA: A Spectrum Eye Recognition Assistant

NASA Astrophysics Data System (ADS)

Yuan, Hailong; Zhang, Haotong; Zhang, Yanxia; Lei, Yajuan; Dong, Yiqiao; Zhao, Yongheng

2018-04-01

ASERA, ASpectrum Eye Recognition Assistant, aids in quasar spectral recognition and redshift measurement and can also be used to recognize various types of spectra of stars, galaxies and AGNs (Active Galactic Nucleus). This interactive software allows users to visualize observed spectra, superimpose template spectra from the Sloan Digital Sky Survey (SDSS), and interactively access related spectral line information. ASERA is an efficient and user-friendly semi-automated toolkit for the accurate classification of spectra observed by LAMOST (the Large Sky Area Multi-object Fiber Spectroscopic Telescope) and is available as a standalone Java application and as a Java applet. The software offers several functions, including wavelength and flux scale settings, zoom in and out, redshift estimation, and spectral line identification.

Pulsar gamma-rays: Spectra luminosities and efficiencies

NASA Technical Reports Server (NTRS)

Harding, A. K.

1980-01-01

The general characteristics of pulsar gamma ray spectra are presented for a model where the gamma rays are produced by curvature radiation from energetic particles above the polar cap and attenuated by pair production. The shape of the spectrum is found to depend on pulsar period, magnetic field strength, and primary particle energy. By a comparison of numerically calculated spectra with the observed spectra of the Crab and Vela pulsars, it is determined that primary particles must be accelerated to energies of about 3 x 10 to the 7th power mc sq. A genaral formula for pulsar gamma ray luminosity is determined and is found to depend on period and field strength.

Fair Shares, Matey, or Walk the Plank

ERIC Educational Resources Information Center

Wilson, P. Holt; Myers, Marrielle; Edgington, Cyndi; Confrey, Jere

2012-01-01

Whether sharing a collection of toys among friends or a pie for dessert, children as young as kindergarten age are keen on making sure that everyone gets their "fair share." In the classroom, fair-sharing activities call for creating equal-size groups from a collection of objects or creating equal-size parts of a whole and are generally used by…

49 CFR 40.399 - How does the Department notify service agents of its decision?

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.399.... The notice includes the following elements: (a) If the decision is not to issue a PIE, a statement of the reasons for the decision, including findings of fact with respect to any material factual issues...

Local police enforcement, public information and education strategies to foster more and proper use of child safety seats by toddlers : evaluation of a demonstration project

DOT National Transportation Integrated Search

1994-03-01

This project evaluated the effects of enforcing safety belt (SB)/child safety seat (CSS) laws and providing public information and education (PI&E) about the laws and use and proper use of CSSs--without external funding. Project goals focused on incr...

RF verification tasks underway at the Harris Corporation for multiple aperture reflector system

NASA Technical Reports Server (NTRS)

Gutwein, T. A.

1982-01-01

Mesh effects on gain and patterns and adjacent aperture coupling effects for "pie" and circular apertures are discussed. Wire effects for Harris model with Langley scale model results included for assessing D/lamda effects, and wire effects with adjacent aperture coupling were determined. Reflector surface distortion effects (pillows and manufacturing roughness) were studied.

Ready, Fire, Aim: The College Campus Gun Fight

ERIC Educational Resources Information Center

Birnbaum, Robert

2013-01-01

The question of whether guns should be permitted on college and university campuses in the United States reflects the tension between two competing perspectives. America has both a robust gun culture and an equally robust (if less well known) gun-control culture. The gun culture is as American as apple pie: There may be as many as 300 million…

Evidence for a "Wild" L2 Grammar: When PPs Rear Their Empty Heads.

ERIC Educational Resources Information Center

Klein, Elaine C.

1995-01-01

Reviews several studies which suggest that some second-language (L2) learners stumble into rogue or "wild" grammars on the road to the L2. L2 learners who have subcategorization knowledge of verbs for their prepositions often omit those same prepositions in relative clauses and questions requiring pied-piping or preposition stranding.…

Apple Pie and Ebonics: Language Diversity and Preparation for a Multicultural World

ERIC Educational Resources Information Center

Martin, Jennifer L.; Martin, Tabitha; Capel, Mandy

2014-01-01

All three of us, the authors, are white and do not speak Ebonics, (or African American Language, AAL). How the misperceptions of AAL impact our students inspired our interest in the subject. The title of this piece refers to the ubiquity of AAL, historically, culturally, as an influential cultural wellspring. Although AAL continues to influence…

A Patient with Phonologic Alexia Can Learn to Read "Much" from "Mud Pies"

ERIC Educational Resources Information Center

Lott, Susan Nitzberg; Sample, Diane M.; Oliver, Robyn T.; Lacey, Elizabeth H.; Friedman, Rhonda B.

2008-01-01

People with phonologic alexia often have difficulty reading functors and verbs, in addition to pseudowords. Friedman et al. [Friedman, R. B., Sample, D. M, & Lott, S. N. (2002). The role of level of representation in the use of paired associate learning for rehabilitation of alexia. "Neuropsychologia, 40", 223-234] reported a successful treatment…

A Causal Analysis of Interrelationships among Exercise, Physical Fitness, and Well-Being in U.S. Navy Personnel

DTIC Science & Technology

1991-08-01

p<.O01 **** p<.0001 Discussion The increasing interest in physical exercise programs over recent ! ears reflects, in part, the conviction that physical...products (e.g., cakes, pies, cookies, candy) eat "leafy" vegetables (e.g., broccoli, cauliflower , cabbage, greens) eat "starchy" vegetables (e.g

Teaching Rhythmic Movement to Children: "Chock-Let Pie"

ERIC Educational Resources Information Center

Hastie, Peter A.; Martin, Ellen H.; Gibson, Gary S.

2005-01-01

It is doubtful that any teacher would question the value of rhythmic movement in a physical education program. The benefits of being able to move rhythmically and to keep a beat are numerous. First, children with rhythm have an increased kinesthetic awareness of their body in motion and stillness. As most physical activities have an inherent…

Getting Gifted Kids Outdoors: Tips for a Summer of Play

ERIC Educational Resources Information Center

Fish, Leigh Ann; Bailie, Patti Ensel

2018-01-01

For many, childhood memories are of outdoor play: "baking" mud pies, building forts, climbing trees, playing tag at the park, and constructing sand castles at the beach. Children today spend only half as much time playing outside as their parents did 30 years ago. Childhood is moving indoors, yet research shows that a lack of outdoor…

49 CFR 40.373 - Before starting a PIE proceeding, does the initiating official give the service agent an...

Code of Federal Regulations, 2010 CFR

2010-10-01

... initiating official give the service agent an opportunity to correct problems? 40.373 Section 40.373... official give the service agent an opportunity to correct problems? (a) If you are a service agent, the... initiating official may conduct appropriate fact finding to verify that you have made and maintained...

Muskox Milk, Ptarmigan Pie and Other Northern Delicacies (Kids Can Cook): Recipes and Related Activities.

ERIC Educational Resources Information Center

Northwest Territories Dept. of Education, Yellowknife.

This profusely illustrated book of recipes encourages the use of foods in children's learning activities, especially foods that are harvested in the Northwest Territories of Canada and that play a role in health maintenance. The activities described also provide an opportunity for children to experience new foods. Introductory material includes…

49 CFR 40.387 - What matters does the Director decide concerning a proposed PIE?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false What matters does the Director decide concerning a... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Public Interest Exclusions § 40.387 What matters does... complete information needed for a decision, the Director may remand the matter to the initiating official...

Diversity and Social Justice--Beyond Motherhood and Apple Pie

ERIC Educational Resources Information Center

Arshad, Rowena

2017-01-01

The majority of teachers are aware that inequalities impact on the lives of individual pupils. For others, there is also deeper awareness of how inequalities impact at community and societal levels. For those who work in areas of multiple deprivation, many are reminded on a daily basis of the "everydayness" of coping or survival for…

Fractions: How to Fair Share

ERIC Educational Resources Information Center

Wilson, P. Holt; Edgington, Cynthia P.; Nguyen, Kenny H.; Pescosolido, Ryan S.; Confrey, Jere

2011-01-01

Children learn from a very early age what it means to get their "fair share." Whether it is candy or birthday cake, many children successfully create equal-size groups or parts of a collection or whole but later struggle to create fair shares of multiple wholes, such as fairly sharing four pies among a family of seven. Recent research suggests…

Graduate Education in 1984 or 1984 or Bye, Bye American Pie?

ERIC Educational Resources Information Center

Porter, D. Thomas; Civikly, Jean M.

This essay suggests a new method of educating graduate students in communication. Students follow a prescribed program of courses and experience leading to the particular career they have chosen. Mastery of each stage must be demonstrated before a student goes to the next. Among the methods used are participation in task forces dealing with a…

ANALYSIS/PLOT: a graphics package for use with the SORT/ANALYSIS data bases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sady, C.A.

1983-08-01

This report describes a graphics package that is used with the SORT/ANALYSIS data bases. The data listed by the SORT/ANALYSIS program can be presented in pie, bar, line, or Gantt chart form. Instructions for the use of the plotting program and descriptions of the subroutines are given in the report.

Digital Revolution or Digital Divide: Will Rural Teachers Get a Piece of the Professional Development Pie?

ERIC Educational Resources Information Center

Broadley, Tania

2010-01-01

In order to sustain the rural education community, access to high quality professional development opportunities must become a priority. Teachers in rural areas face many challenges in order to access professional learning equitable to their city counterparts. In the current climate, the Federal government of Australia is committed to initiatives…

Food Service Worker. Instructional Modules for Food Management, Production and Services. Modules 35-52. Competency Based Curriculum.

ERIC Educational Resources Information Center

Tennessee Univ., Knoxville. Dept. of Vocational-Technical Education.

These 18 teacher modules are part of a curriculum dealing with food management, production, and services that was developed for use in secondary and postsecondary vocational programs in Tennessee. Covered in the individual modules are quickbreads, pies, icings and toppings, specialty cakes, specialty desserts, yeast products, cream puff and puff…

El Universo a Sus Pies: Actividades y Recursos para Astronomia (Universe at Your Fingertips: An Astronomy Activity and Resource Notebook).

ERIC Educational Resources Information Center

Fraknoi, Andrew, Ed.; Schatz, Dennis, Ed.

The goal of this resource notebook is to provide activities selected by astronomers and classroom teachers, comprehensive resource lists and bibliographies, background material on astronomical topics, and teaching ideas from experienced astronomy educators. Activities are grouped into several major areas of study in astronomy including lunar…

Uncertainty and Complexity in Mathematical Modeling

ERIC Educational Resources Information Center

Cannon, Susan O.; Sanders, Mark

2017-01-01

Modeling is an effective tool to help students access mathematical concepts. Finding a math teacher who has not drawn a fraction bar or pie chart on the board would be difficult, as would finding students who have not been asked to draw models and represent numbers in different ways. In this article, the authors will discuss: (1) the properties of…

Rock and Roll! Using Classic Rock as a Guide to Fantasy-Theme Analysis

ERIC Educational Resources Information Center

Waite, Lisa

2008-01-01

This article presents an activity which makes use of Don McLean's song "American Pie," to engage students in fantasy-theme analysis. This discussion ultimately demonstrates how reality is constructed to satisfy the views shared by groups and individuals. Fantasy-theme analysis argues that audiences frequently shape their own connotation of an…

Living and Learning in EcCoWell Cities: Discussion Paper

ERIC Educational Resources Information Center

Kearns, Peter

2012-01-01

These notes and questions have been prepared to promote discussion of the ideas set out in the Clarifying paper, "Living and learning in EcCoWell cities" to be found on the PASCAL International Exchanges (PIE) website. This Discussion Paper sets ten questions for discussion. We are hoping to encourage discussions of these issues around the world.

Analysis of PANDA Passive Containment Cooling Steady-State Tests with the Spectra Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stempniewicz, Marek M

2000-07-15

Results of post test simulation of the PANDA passive containment cooling (PCC) steady-state tests (S-series tests), performed at the PANDA facility at the Paul Scherrer Institute, Switzerland, are presented. The simulation has been performed using the computer code SPECTRA, a thermal-hydraulic code, designed specifically for analyzing containment behavior of nuclear power plants.Results of the present calculations are compared to the measurement data as well as the results obtained earlier with the codes MELCOR, TRAC-BF1, and TRACG. The calculated PCC efficiencies are somewhat lower than the measured values. Similar underestimation of PCC efficiencies had been obtained in the past, with themore » other computer codes. To explain this difference, it is postulated that condensate coming into the tubes forms a stream of liquid in one or two tubes, leaving most of the tubes unaffected. The condensate entering the water box is assumed to fall down in the form of droplets. With these assumptions, the results calculated with SPECTRA are close to the experimental data.It is concluded that the SPECTRA code is a suitable tool for analyzing containments of advanced reactors, equipped with passive containment cooling systems.« less

High-resolution investigation of longitudinal modes of a GaN-based blue laser diode

NASA Astrophysics Data System (ADS)

Al-Basheer, Watheq; Aljalal, Abdulaziz; Gasmi, Khaled; Adigun, Taofeek O.

2017-05-01

Typical emission spectra of GaN-based blue laser diodes are known to have irregular shapes. Hence, well-resolved study of their spectra may help in understanding the origin of their spectral shapes irregularity. In this paper, the spectra of a commercial GaN-based blue laser diode are studied as a function of injection current and temperature using a spectrometer with highresolution of 0.003-nm over the spectral region 440 - 450 nm. The obtained laser spectra are used to track the longitudinal modes evolution as a function of operating currents and temperatures as well as to precisely map single mode operation. In addition, yielded laser spectra will be utilized to evaluate few parameters related to the laser diode, such as mode spacing, optical gain, slope efficiency and threshold current at certain temperature.

Proposal and evaluation of subordinate standard solar irradiance spectra for applications in solar energy systems

DOE PAGES

Jessen, Wilko; Wilbert, Stefan; Gueymard, Christian A.; ...

2018-04-10

Reference solar irradiance spectra are needed to specify key parameters of solar technologies such as photovoltaic cell efficiency, in a comparable way. The IEC 60904-3 and ASTM G173 standards present such spectra for Direct Normal Irradiance (DNI) and Global Tilted Irradiance (GTI) on a 37 degrees tilted sun-facing surface for one set of clear-sky conditions with an air mass of 1.5 and low aerosol content. The IEC/G173 standard spectra are the widely accepted references for these purposes. Hence, the authors support the future replacement of the outdated ISO 9845 spectra with the IEC spectra within the ongoing update of thismore » ISO standard. The use of a single reference spectrum per component of irradiance is important for clarity when comparing and rating solar devices such as PV cells. However, at some locations the average spectra can differ strongly from those defined in the IEC/G173 standards due to widely different atmospheric conditions and collector tilt angles. Therefore, additional subordinate standard spectra for other atmospheric conditions and tilt angles are of interest for a rough comparison of product performance under representative field conditions, in addition to using the main standard spectrum for product certification under standard test conditions. This simplifies the product selection for solar power systems when a fully-detailed performance analysis is not feasible (e.g. small installations). Also, the effort for a detailed yield analyses can be reduced by decreasing the number of initial product options. After appropriate testing, this contribution suggests a number of additional spectra related to eight sets of atmospheric conditions and tilt angles that are currently considered within ASTM and ISO working groups. The additional spectra, called subordinate standard spectra, are motivated by significant spectral mismatches compared to the IEC/G173 spectra (up to 6.5%, for PV at 37 degrees tilt and 10-15% for CPV). These mismatches correspond to potential accuracy improvements for a quick estimation of the average efficiency by applying the appropriate subordinate standard spectrum instead of the IEC/G173 spectra. The applicability of these spectra for PV performance analyses is confirmed at five test sites, for which subordinate spectra could be intuitively selected based on the average atmospheric aerosol optical depth (AOD) and precipitable water vapor at those locations. The development of subordinate standard spectra for DNI and concentrating solar power (CSP) and concentrating PV (CPV) is also considered. However, it is found that many more sets of atmospheric conditions would be required to allow the intuitive selection of DNI spectra for the five test sites, due in particular to the stronger effect of AOD on DNI compared to GTI. The matrix of subordinate GTI spectra described in this paper are recommended to appear as an option in the annex of future standards, in addition to the obligatory use of the main spectrum from the ASTM G173 and IEC 60904 standards.« less

Proposal and evaluation of subordinate standard solar irradiance spectra for applications in solar energy systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jessen, Wilko; Wilbert, Stefan; Gueymard, Christian A.

Reference solar irradiance spectra are needed to specify key parameters of solar technologies such as photovoltaic cell efficiency, in a comparable way. The IEC 60904-3 and ASTM G173 standards present such spectra for Direct Normal Irradiance (DNI) and Global Tilted Irradiance (GTI) on a 37 degrees tilted sun-facing surface for one set of clear-sky conditions with an air mass of 1.5 and low aerosol content. The IEC/G173 standard spectra are the widely accepted references for these purposes. Hence, the authors support the future replacement of the outdated ISO 9845 spectra with the IEC spectra within the ongoing update of thismore » ISO standard. The use of a single reference spectrum per component of irradiance is important for clarity when comparing and rating solar devices such as PV cells. However, at some locations the average spectra can differ strongly from those defined in the IEC/G173 standards due to widely different atmospheric conditions and collector tilt angles. Therefore, additional subordinate standard spectra for other atmospheric conditions and tilt angles are of interest for a rough comparison of product performance under representative field conditions, in addition to using the main standard spectrum for product certification under standard test conditions. This simplifies the product selection for solar power systems when a fully-detailed performance analysis is not feasible (e.g. small installations). Also, the effort for a detailed yield analyses can be reduced by decreasing the number of initial product options. After appropriate testing, this contribution suggests a number of additional spectra related to eight sets of atmospheric conditions and tilt angles that are currently considered within ASTM and ISO working groups. The additional spectra, called subordinate standard spectra, are motivated by significant spectral mismatches compared to the IEC/G173 spectra (up to 6.5%, for PV at 37 degrees tilt and 10-15% for CPV). These mismatches correspond to potential accuracy improvements for a quick estimation of the average efficiency by applying the appropriate subordinate standard spectrum instead of the IEC/G173 spectra. The applicability of these spectra for PV performance analyses is confirmed at five test sites, for which subordinate spectra could be intuitively selected based on the average atmospheric aerosol optical depth (AOD) and precipitable water vapor at those locations. The development of subordinate standard spectra for DNI and concentrating solar power (CSP) and concentrating PV (CPV) is also considered. However, it is found that many more sets of atmospheric conditions would be required to allow the intuitive selection of DNI spectra for the five test sites, due in particular to the stronger effect of AOD on DNI compared to GTI. The matrix of subordinate GTI spectra described in this paper are recommended to appear as an option in the annex of future standards, in addition to the obligatory use of the main spectrum from the ASTM G173 and IEC 60904 standards.« less

Blackbody absorption efficiencies for six lamp pumped Nd laser materials

NASA Technical Reports Server (NTRS)

Cross, Patricia L.; Barnes, Norman P.; Skolaut, Milton W., Jr.; Storm, Mark E.

1990-01-01

Utilizing high resolution spectra, the absorption efficiencies for six Nd laser materials were calculated as functions of the effective blackbody temperature of the lamp and laser crystal size. The six materials were Nd:YAG, Nd:YLF, Nd:Q-98 Glass, Nd:YVO4, Nd:BEL, and Nd:Cr:GSGG. Under the guidelines of this study, Nd:Cr:GSGG's absorption efficiency is twice the absorption efficiency of any of the other laser materials.

Efficient "on-the-fly" calculation of Raman spectra from ab-initio molecular dynamics: Application to hydrophobic/hydrophilic solutes in bulk water.

PubMed

Partovi-Azar, Pouya; Kühne, Thomas D

2015-11-05

We present a novel computational method to accurately calculate Raman spectra from first principles. Together with an extension of the second-generation Car-Parrinello method of Kühne et al. (Phys. Rev. Lett. 2007, 98, 066401) to propagate maximally localized Wannier functions together with the nuclei, a speed-up of one order of magnitude can be observed. This scheme thus allows to routinely calculate finite-temperature Raman spectra "on-the-fly" by means of ab-initio molecular dynamics simulations. To demonstrate the predictive power of this approach we investigate the effect of hydrophobic and hydrophilic solutes in water solution on the infrared and Raman spectra. © 2015 Wiley Periodicals, Inc.

Spectroscopic study of surface enhanced Raman scattering of caffeine on borohydride-reduced silver colloids

NASA Astrophysics Data System (ADS)

Chen, Xiaomin; Gu, Huaimin; Shen, Gaoshan; Dong, Xiao; Kang, Jian

2010-06-01

The surface enhanced Raman scattering (SERS) of caffeine on borohydride-reduced silver colloids system under different aqueous solution environment has been studied in this paper. The relative intensity of SERS of caffeine significantly varies with different concentrations of sodium chloride and silver particles. However, at too high or too low concentration of sodium chloride and silver particle, the enhancement of SERS spectra is not evident. The SERS spectra of caffeine suggest that the contribution of the charge transfer mechanism to SERS may be dominant. The chloride ions can significantly enhance the efficiency of SERS, while the enhancement is selective, as the efficiency in charge transfer enhancement is higher than in electromagnetic enhancement. Therefore, it can be concluded that the active site of chloride ion locates on the bond between the caffeine and the silver surface. In addition, the SERS spectra of caffeine on borohydride-reduced and citrate-reduced silver colloids are different, which may be due to different states caffeine adsorbed on silver surface under different silver colloids.

Development of potent in vivo mutagenesis plasmids with broad mutational spectra

PubMed Central

Badran, Ahmed H.; Liu, David R.

2015-01-01

Methods to enhance random mutagenesis in cells offer advantages over in vitro mutagenesis, but current in vivo methods suffer from a lack of control, genomic instability, low efficiency and narrow mutational spectra. Using a mechanism-driven approach, we created a potent, inducible, broad-spectrum and vector-based mutagenesis system in E. coli that enhances mutation 322,000-fold over basal levels, surpassing the mutational efficiency and spectra of widely used in vivo and in vitro methods. We demonstrate that this system can be used to evolve antibiotic resistance in wild-type E. coli in <24 h, outperforming chemical mutagens, ultraviolet light and the mutator strain XL1-Red under similar conditions. This system also enables the continuous evolution of T7 RNA polymerase variants capable of initiating transcription using the T3 promoter in <10 h. Our findings enable broad-spectrum mutagenesis of chromosomes, episomes and viruses in vivo, and are applicable to both bacterial and bacteriophage-mediated laboratory evolution platforms. PMID:26443021

Development of potent in vivo mutagenesis plasmids with broad mutational spectra.

PubMed

Badran, Ahmed H; Liu, David R

2015-10-07

Methods to enhance random mutagenesis in cells offer advantages over in vitro mutagenesis, but current in vivo methods suffer from a lack of control, genomic instability, low efficiency and narrow mutational spectra. Using a mechanism-driven approach, we created a potent, inducible, broad-spectrum and vector-based mutagenesis system in E. coli that enhances mutation 322,000-fold over basal levels, surpassing the mutational efficiency and spectra of widely used in vivo and in vitro methods. We demonstrate that this system can be used to evolve antibiotic resistance in wild-type E. coli in <24 h, outperforming chemical mutagens, ultraviolet light and the mutator strain XL1-Red under similar conditions. This system also enables the continuous evolution of T7 RNA polymerase variants capable of initiating transcription using the T3 promoter in <10 h. Our findings enable broad-spectrum mutagenesis of chromosomes, episomes and viruses in vivo, and are applicable to both bacterial and bacteriophage-mediated laboratory evolution platforms.

Temporal contrast enhancement of a femtosecond fiber CPA system by filtering of SPM broadened spectra

NASA Astrophysics Data System (ADS)

Buldt, J.; Müller, M.; Klas, R.; Eidam, T.; Limpert, J.; Tünnermann, A.

2018-02-01

We present a novel approach for temporal contrast enhancement of energetic laser pulses by filtered SPM broadened spectra. A measured temporal contrast enhancement by at least 7 orders of magnitude in a simple setup has been achieved. This technique is applicable to a wide range of laser parameters and poses a highly efficient alternative to existing contrast-enhancement methods.

Monitoring Prepregs As They Cure

NASA Technical Reports Server (NTRS)

Young, P. R.; Gleason, J. R.; Chang, A. C.

1986-01-01

Quality IR spectra obtained in dynamic heating environment. New technique obtains quality infrared spectra on graphite-fiber-reinforced, polymeric-matrix-resin prepregs as they cure. Technique resulted from modification of diffuse reflectance/Fourier transform infrared (DR/FTIR) technique previously used to analyze environmentally exposed cured graphite composites. Technique contribute to better understanding of prepreg chemistry/temperature relationships and development of more efficient processing cycles for advanced materials.

Hubert: Software for efficient analysis of in-situ nuclear forward scattering experiments

NASA Astrophysics Data System (ADS)

Vrba, Vlastimil; Procházka, Vít; Smrčka, David; Miglierini, Marcel

2016-10-01

Combination of short data acquisition time and local investigation of a solid state through hyperfine parameters makes nuclear forward scattering (NFS) a unique experimental technique for investigation of fast processes. However, the total number of acquired NFS time spectra may be very high. Therefore an efficient way of the data evaluation is needed. In this paper we report the development of Hubert software package as a response to the rapidly developing field of in-situ NFS experiments. Hubert offers several useful features for data files processing and could significantly shorten the evaluation time by using a simple connection between the neighboring time spectra through their input and output parameter values.

Kerr-gated picosecond Raman spectroscopy and Raman photon migration of equine bone tissue with 400-nm excitation

NASA Astrophysics Data System (ADS)

Morris, Michael D.; Goodship, Allen E.; Draper, Edward R. C.; Matousek, Pavel; Towrie, Michael; Parker, Anthony W.

2004-07-01

We show that Raman spectroscopy with visible lasers, even in the deep blue is possible with time-gated Raman spectroscopy. A 4 picosec time gate allows efficient fluorescence rejection, up to 1000X, and provides almost background-free Raman spectra with low incident laser power. The technology enables spectroscopy with better than 10X higher scattering efficiency than is possible with the NIR (785 nm and 830 nm) lasers that are conventionally used. Raman photon migration is shown to allow depth penetration. We show for the first time that Kerr-gated Raman spectra of bone tissue with blue laser excitation enables both fluorescence rejection and depth penetration.

Theoretical tuning of the firefly bioluminescence spectra by the modification of oxyluciferin

NASA Astrophysics Data System (ADS)

Cheng, Yuan-Yuan; Zhu, Jia; Liu, Ya-Jun

2014-01-01

Extending the firefly bioluminescence is of practical significance for the improved visualization of living cells and the development of a multicolor reporter. Tuning the color of bioluminescence in fireflies mainly involves the modification of luciferase and luciferin. In this Letter, we theoretically studied the emission spectra of 9 firefly oxyluciferin analogs in the gas phase and in solutions. Three density functionals, including B3LYP, CAM-B3LYP and M06-2X, were employed to theoretically predict the efficiently luminescent analogs. The reliable functionals for calculating the targeted systems were suggested. The luminescence efficiency, solvent effects, and substituent effects are discussed based on the calculated results.

Variable selection based on clustering analysis for improvement of polyphenols prediction in green tea using synchronous fluorescence spectra

NASA Astrophysics Data System (ADS)

Shan, Jiajia; Wang, Xue; Zhou, Hao; Han, Shuqing; Riza, Dimas Firmanda Al; Kondo, Naoshi

2018-04-01

Synchronous fluorescence spectra, combined with multivariate analysis were used to predict flavonoids content in green tea rapidly and nondestructively. This paper presented a new and efficient spectral intervals selection method called clustering based partial least square (CL-PLS), which selected informative wavelengths by combining clustering concept and partial least square (PLS) methods to improve models’ performance by synchronous fluorescence spectra. The fluorescence spectra of tea samples were obtained and k-means and kohonen-self organizing map clustering algorithms were carried out to cluster full spectra into several clusters, and sub-PLS regression model was developed on each cluster. Finally, CL-PLS models consisting of gradually selected clusters were built. Correlation coefficient (R) was used to evaluate the effect on prediction performance of PLS models. In addition, variable influence on projection partial least square (VIP-PLS), selectivity ratio partial least square (SR-PLS), interval partial least square (iPLS) models and full spectra PLS model were investigated and the results were compared. The results showed that CL-PLS presented the best result for flavonoids prediction using synchronous fluorescence spectra.

Variable selection based on clustering analysis for improvement of polyphenols prediction in green tea using synchronous fluorescence spectra.

PubMed

Shan, Jiajia; Wang, Xue; Zhou, Hao; Han, Shuqing; Riza, Dimas Firmanda Al; Kondo, Naoshi

2018-03-13

Synchronous fluorescence spectra, combined with multivariate analysis were used to predict flavonoids content in green tea rapidly and nondestructively. This paper presented a new and efficient spectral intervals selection method called clustering based partial least square (CL-PLS), which selected informative wavelengths by combining clustering concept and partial least square (PLS) methods to improve models' performance by synchronous fluorescence spectra. The fluorescence spectra of tea samples were obtained and k-means and kohonen-self organizing map clustering algorithms were carried out to cluster full spectra into several clusters, and sub-PLS regression model was developed on each cluster. Finally, CL-PLS models consisting of gradually selected clusters were built. Correlation coefficient (R) was used to evaluate the effect on prediction performance of PLS models. In addition, variable influence on projection partial least square (VIP-PLS), selectivity ratio partial least square (SR-PLS), interval partial least square (iPLS) models and full spectra PLS model were investigated and the results were compared. The results showed that CL-PLS presented the best result for flavonoids prediction using synchronous fluorescence spectra.

Algorithms for classification of astronomical object spectra

NASA Astrophysics Data System (ADS)

Wasiewicz, P.; Szuppe, J.; Hryniewicz, K.

2015-09-01

Obtaining interesting celestial objects from tens of thousands or even millions of recorded optical-ultraviolet spectra depends not only on the data quality but also on the accuracy of spectra decomposition. Additionally rapidly growing data volumes demands higher computing power and/or more efficient algorithms implementations. In this paper we speed up the process of substracting iron transitions and fitting Gaussian functions to emission peaks utilising C++ and OpenCL methods together with the NOSQL database. In this paper we implemented typical astronomical methods of detecting peaks in comparison to our previous hybrid methods implemented with CUDA.

Saturn systems holddown acoustic efficiency and normalized acoustic power spectrum.

NASA Technical Reports Server (NTRS)

Gilbert, D. W.

1972-01-01

Saturn systems field acoustic data are used to derive mid- and far-field prediction parameters for rocket engine noise. The data were obtained during Saturn vehicle launches at the Kennedy Space Center. The data base is a sorted set of acoustic data measured during the period 1961 through 1971 for Saturn system launches SA-1 through AS-509. The model assumes hemispherical radiation from a simple source located at the intersection of the longitudinal axis of each booster and the engine exit plane. The model parameters are evaluated only during vehicle holddown. The acoustic normalized power spectrum and efficiency for each system are isolated as a composite from the data using linear numerical methods. The specific definitions of each allows separation. The resulting power spectra are nondimensionalized as a function of rocket engine parameters. The nondimensional Saturn system acoustic spectrum and efficiencies are compared as a function of Strouhal number with power spectra from other systems.

Apoferritin fibers: a new template for 1D fluorescent hybrid nanostructures

NASA Astrophysics Data System (ADS)

Jurado, Rocío; Castello, Fabio; Bondia, Patricia; Casado, Santiago; Flors, Cristina; Cuesta, Rafael; Domínguez-Vera, José M.; Orte, Angel; Gálvez, Natividad

2016-05-01

Recently, research in the field of protein amyloid fibers has gained great attention due to the use of these materials as nanoscale templates for the construction of functional hybrid materials. The formation of apoferritin amyloid-like protein fibers is demonstrated herein for the first time. The morphology, size and stiffness of these one-dimensional structures are comparable to the fibers formed by β-lactoglobulin, a protein frequently used as a model in the study of amyloid-like fibrillar proteins. Nanometer-sized globular apoferritin is capable of self-assembling to form 1D micrometer-sized structures after being subjected to a heating process. Depending on the experimental conditions, fibers with different morphologies and sizes are obtained. The wire-like protein structure is rich in functional groups and allows chemical functionalization with diverse quantum dots (QD), as well as with different Alexa Fluor (AF) dyes, leading to hybrid fluorescent fibers with variable emission wavelengths, from green to near infrared, depending on the QD and AFs coupled. For fibers containing the pair AF488 and AF647, efficient fluorescence energy transfer from the covalently coupled donor (AF488) to acceptor tags (AF647) takes place. Apoferritin fibers are proposed here as a new promising template for obtaining hybrid functional materials.Recently, research in the field of protein amyloid fibers has gained great attention due to the use of these materials as nanoscale templates for the construction of functional hybrid materials. The formation of apoferritin amyloid-like protein fibers is demonstrated herein for the first time. The morphology, size and stiffness of these one-dimensional structures are comparable to the fibers formed by β-lactoglobulin, a protein frequently used as a model in the study of amyloid-like fibrillar proteins. Nanometer-sized globular apoferritin is capable of self-assembling to form 1D micrometer-sized structures after being subjected to a heating process. Depending on the experimental conditions, fibers with different morphologies and sizes are obtained. The wire-like protein structure is rich in functional groups and allows chemical functionalization with diverse quantum dots (QD), as well as with different Alexa Fluor (AF) dyes, leading to hybrid fluorescent fibers with variable emission wavelengths, from green to near infrared, depending on the QD and AFs coupled. For fibers containing the pair AF488 and AF647, efficient fluorescence energy transfer from the covalently coupled donor (AF488) to acceptor tags (AF647) takes place. Apoferritin fibers are proposed here as a new promising template for obtaining hybrid functional materials. Electronic supplementary information (ESI) available: TEM images of ferritin protein fiber formation, and apoferritin after 18 days of heat treatment; FLIM-PIE technique details; fluorescence emission spectra of apoferritin and β-lactoglobulin fibers functionalized with different QDs. See DOI: 10.1039/c6nr01044j

Unequal Pieces of a Shrinking Pie: The Struggle between African Americans and Latinos over Education, Employment, and Empowerment in Compton, California

ERIC Educational Resources Information Center

Straus, Emily E.

2009-01-01

This article discusses the role of education within communities and underscores the changing nature of minority groups in the United States. It specifically examines the struggle between African Americans and Latinos over education, employment, and empowerment in Compton, California. The story of Compton and its school district exposes…

Muskox Milk, Ptarmigan Pie and Other Northern Delicacies (Kids Can Cook): Guide to Parents and Teachers.

ERIC Educational Resources Information Center

Northwest Territories Dept. of Education, Yellowknife.

This guide for parents and teachers encourages the use of foods in children's learning activities, especially foods that are harvested in the Northwest Territories of Canada and that play a role in health maintenance. The activities also provide an opportunity for children to experience new foods. Sections in the guide discuss: (1) nutrition,…

The Agony and the Ecstasy: Current Status of Hispanic Individuals' Achievement in Higher Education and Earnings - With a Glimpse to the Future

ERIC Educational Resources Information Center

De Los Santos, Gilberto; Asgary, Nader; Nazemzadeh, Asghar; DeShields, Jr., Oscar W.

2005-01-01

Some projections about Hispanic individuals point to a rosy picture regarding gains in higher educational enrollment. Other studies lament that these gains are, at best, minimal. Although the so-called higher education pie is undoubtedly expanding, this article concludes that Hispanic adults are losing, rather than gaining, educational attainment…

An Evaluation of the Program To Improve Elementary Science (PIES).

ERIC Educational Resources Information Center

Zielinski, Edward J.; Smith, Bruce G.

The purposes of this study were to determine (1) whether or not the participants of the program demonstrated significant gains in knowledge and attitudes as a result of the courses; (2) whether the gains persisted over time; and (3) if there was an associated increase in the participants' proclivity to do science which was also stable over time.…

Issues around Creating a Reusable Learning Object to Support Statistics Teaching

ERIC Educational Resources Information Center

Gilchrist, Mollie

2007-01-01

Although our health professional students have some experience of simple charts, such as pie and bar, and some intuition of histograms, they do not appear to have much knowledge or understanding about box and whisker plots and their relation to the data they are describing or compared to histograms. The boxplot is a versatile charting tool, useful…

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (78th, Washington, DC, August 9-12, 1995). Visual Communication Division.

ERIC Educational Resources Information Center

Association for Education in Journalism and Mass Communication.

The visual communication section of the Proceedings contains the following 8 papers: "Constructing Meaning from Visual Images in Local Television Crime News" (Claudette Guzan Artwick); "Comparative Performance of the Pie and the Bar" (Prabu David); "Job Satisfaction among Photojournalists past 40: A National Survey Looks…

African-American Communities in Economic Crisis: Adult Educators Investing in the Human Capital Development of the Urban Poor

ERIC Educational Resources Information Center

Stephens, Mattyna L.

2010-01-01

Through discourse analysis the research will unearth the tension between the Theories of Human Capital (HCT) and the Work First Policy (WFP), Policies Informing Education (PIE), and Human Capital Development (HCD) as they relate to the labor market. The application of discourse analysis demonstrates how the tenants of HCT are missing components…

A Fair Slice of the Pie? Problematising the Dispersal of Government Funds to Australian Universities

ERIC Educational Resources Information Center

Heffernan, Troy A.

2017-01-01

A common theme in higher education research is the factors that affect university funding. Studies frequently examine how universities cope with funding cuts and the changes that have stemmed from operating in a neoliberal age, a period that now sees institutions commonly functioning on a cost/benefit basis. This paper offers an original…

Smaller Slices of the Pie. The Growing Economic Vulnerability of Poor and Moderate Income Americans.

ERIC Educational Resources Information Center

Porter, Kathryn; And Others

Data which demonstrate increasing poverty in the United States are collected in this report. Following a brief introduction, six sections present information to support these major findings: (1) Today there is a growing trend toward income disparity between rich and poor. Americans of moderate incomes as well as those classified as poor have lost…

Introduction to Statistics. Learning Packages in the Policy Sciences Series, PS-26. Revised Edition.

ERIC Educational Resources Information Center

Policy Studies Associates, Croton-on-Hudson, NY.

The primary objective of this booklet is to introduce students to basic statistical skills that are useful in the analysis of public policy data. A few, selected statistical methods are presented, and theory is not emphasized. Chapter 1 provides instruction for using tables, bar graphs, bar graphs with grouped data, trend lines, pie diagrams,…

The 1960s &'70s: Creative Activities for Teaching American History. Teacher's Guide. Revised.

ERIC Educational Resources Information Center

Stevens, Lawrence

The activities in this manual explore some of the issues of the 1960s and 1970s that reflected changes in U.S. patterns of thought: minorities sought their share of the American pie; young people challenged established authority; massive protests erupted against the Vietnam War; political corruption was found in high office and a marked change…

Getting a Grip on Librarian Evaluation

ERIC Educational Resources Information Center

Jaeger, Paige

2013-01-01

When the Common Core State Standards (CCSS) were adopted in many states, it was only one piece of the pie called Race to the Top (RttT). As states competed and clamored to win the Race to the Top dollars, they knew it came with strings attached. The biggest piece of string is called APPR, or Annual Professional Performance Review--and it is more…

Extraneous Information and Graph Comprehension: Implications for Effective Design Choices

ERIC Educational Resources Information Center

Stewart, Brandie M.; Cipolla, Jessica M.; Best, Lisa A.

2009-01-01

Purpose: The purpose of this paper is to examine if university students could accurately extract information from graphs presented in 2D or 3D formats with different colour hue variations or solid black and white. Design/methodology/approach: Participants are presented with 2D and 3D bar and pie charts in a PowerPoint presentation and are asked to…

Blue Tigers, Black Tapirs, & the Pied Raven of the Faroe Islands: Teaching Genetic Drift Using Real-Life Animal Examples

ERIC Educational Resources Information Center

Robischon, Marcel

2015-01-01

Genetic drift is a concept of population genetics that is central to understanding evolutionary processes and aspects of conservation biology. It is frequently taught using rather abstract representations. I introduce three real-life zoological examples, based on historical and recent color morphs of tigers, tapirs, and ravens, that can complement…

The influence of aesthetic surgery on the profile of emotion.

PubMed

Rubesa, Gordana; Tic-Bacić, Tamara; Svesko-Visentin, Helena; Bacić, Giordano

2011-09-01

In the clinical practise it has been observed that the person changes physically, too, after aesthetic surgery. The aim of this work was to examine, by objective psychological measurements, what changes occur, and what personality features change. Forty six subjects that had an aesthetic surgery were examined; they were tested before, and eighteen month after the surgery by the Profile Index of Emotion (PIE). Before the re-testing the subjects were analyzed by "The Life Events Scale" to exclude the possibility of the influence of new life events on the results of the re-test. The control group of 29 volunteers was tested by the same psychological instruments. The control group never verbalized the wish for an aesthetic surgery; they were never in psychiatric treatment, and the corresponded to the experimental group in the age, sex and education level. Analysis of the data obtained from PIE test before and after the operation shows a statistical significant increase of the adaptability segments and an improvement of capacity for taking and giving. Emotional conflict does not disappear, but a new balance is established, satisfaction is higher, and the identity is more integrated.

How to reduce the effect of framing on messages about health.

PubMed

Garcia-Retamero, Rocio; Galesic, Mirta

2010-12-01

Patients must be informed about risks before any treatment can be implemented. Yet serious problems in communicating these risks occur because of framing effects. To investigate the effects of different information frames when communicating health risks to people with high and low numeracy and determine whether these effects can be countered or eliminated by using different types of visual displays (i.e., icon arrays, horizontal bars, vertical bars, or pies). Experiment on probabilistic, nationally representative US (n = 492) and German (n = 495) samples, conducted in summer 2008. Participants' risk perceptions of the medical risk expressed in positive (i.e., chances of surviving after surgery) and negative (i.e., chances of dying after surgery) terms. Although low-numeracy people are more susceptible to framing than those with high numeracy, use of visual aids is an effective method to eliminate its effects. However, not all visual aids were equally effective: pie charts and vertical and horizontal bars almost completely removed the effect of framing. Icon arrays, however, led to a smaller decrease in the framing effect. Difficulties with understanding numerical information often do not reside in the mind, but in the representation of the problem.

Foveolar Müller Cells of the Pied Flycatcher: Morphology and Distribution of Intermediate Filaments Regarding Cell Transparency.

PubMed

Zueva, Lidia; Golubeva, Tatiana; Korneeva, Elena; Makarov, Vladimir; Khmelinskii, Igor; Inyushin, Mikhail

2016-04-01

Specialized intermediate filaments (IFs) have critical importance for the clearness and uncommon transparency of vertebrate lens fiber cells, although the physical mechanisms involved are poorly understood. Recently, an unusual low-scattering light transport was also described in retinal Müller cells. Exploring the function of IFs in Müller cells, we have studied the morphology and distribution pattern of IFs and other cytoskeletal filaments inside the Müller cell main processes in the foveolar part of the avian (pied flycatcher) retina. We found that some IFs surrounded by globular nanoparticles (that we suggest are crystallines) are present in almost every part of the Müller cells that span the retina, including the microvilli. Unlike IFs implicated in the mechanical architecture of the cell, these IFs are not connected to any specific cellular membranes. Instead, they are organized into bundles, passing inside the cell from the endfeet to the photoreceptor, following the geometry of the processes, and repeatedly circumventing numerous obstacles. We believe that the presently reported data effectively confirm that the model of nanooptical channels built of the IFs may provide a viable explanation of Müller cell transparency.

Data on the distribution of cancer incidence and death across age and sex groups visualized using multilevel spie charts.

PubMed

Feitelson, Dror G

2016-04-01

Cancer incidence and death statistics are typically recorded for multiple age and sex brackets, leading to large data tables which are difficult to digest. Effective visualizations of this data would allow practitioners, policy makers, and the general public to comprehend the data more readily and act on it appropriately. We introduce multilevel spie charts to create a combined visualization of cancer incidence and death statistics. Spie charts combine multiple pie charts, where the base pie chart (representing the general population) is used to set the angles of slices, and the superimposed ones use variable radii to portray the cancer data. Spie charts of cancer incidence and death statistics from Israel for 2009-2011 are used as an illustration. These charts clearly show various patterns of how cancer incidence and death distribute across age and sex groups, illustrating (1) absolute numbers and (2) rates per 100,000 population for different age and sex brackets. In addition, drawing separate charts for different cancer types illustrates relative mortality, both (3) across cancer types and (4) mortality relative to incidence. Naturally, this graphical depiction can be used for other diseases as well. Copyright © 2016 Elsevier Inc. All rights reserved.

Finite-beta equilibria for Wendelstein 7-X configurations using the Princeton Iterative Equilibrium Solver code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arndt, S.; Merkel, P.; Monticello, D.A.

Fixed- and free-boundary equilibria for Wendelstein 7-X (W7-X) [W. Lotz {ital et al.}, {ital Plasma Physics and Controlled Nuclear Fusion Research 1990} (Proc. 13th Int. Conf. Washington, DC, 1990), (International Atomic Energy Agency, Vienna, 1991), Vol. 2, p. 603] configurations are calculated using the Princeton Iterative Equilibrium Solver (PIES) [A. H. Reiman {ital et al.}, Comput. Phys. Commun., {bold 43}, 157 (1986)] to deal with magnetic islands and stochastic regions. Usually, these W7-X configurations require a large number of iterations for PIES convergence. Here, two methods have been successfully tested in an attempt to decrease the number of iterations neededmore » for convergence. First, periodic sequences of different blending parameters are used. Second, the initial guess is vastly improved by using results of the Variational Moments Equilibrium Code (VMEC) [S. P. Hirshmann {ital et al.}, Phys. Fluids {bold 26}, 3553 (1983)]. Use of these two methods have allowed verification of the Hamada condition and tendency of {open_quotes}self-healing{close_quotes} of islands has been observed. {copyright} {ital 1999 American Institute of Physics.}« less

Trade-offs between sexual advertisement and immune function in the pied flycatcher (Ficedula hypoleuca).

PubMed

Kilpimaa, Janne; Alatalo, Rauno V; Siitari, Heli

2004-02-07

Good genes models of sexual selection assume that sexual advertisement is costly and thus the level of advertisement honestly reveals heritable viability. Recently it has been suggested that an important cost of sexual advertisement might be impairment of the functioning of the immune system. In this field experiment we investigated the possible trade-offs between immune function and sexual advertisement by manipulating both mating effort and activity of immune defence in male pied flycatchers. Mating effort was increased in a non-arbitrary manner by removing females from mated males during nest building. Widowed males sustained higher haematocrit levels than control males and showed higher expression of forehead patch height, suggesting that manipulation succeeded in increasing mating effort. Males that were experimentally forced to increase mating effort had reduced humoral immune responsiveness compared with control males. In addition, experimental activation of immune defence by vaccination with novel antigens reduced the expression of male ornament dimensions. To conclude, our results indicate that causality behind the trade-off between immune function and sexual advertisement may work in both directions: sexual activity suppresses immune function but immune challenge also reduces sexual advertisement.

Trade-offs between sexual advertisement and immune function in the pied flycatcher (Ficedula hypoleuca).

PubMed Central

Kilpimaa, Janne; Alatalo, Rauno V.; Siitari, Heli

2004-01-01

Good genes models of sexual selection assume that sexual advertisement is costly and thus the level of advertisement honestly reveals heritable viability. Recently it has been suggested that an important cost of sexual advertisement might be impairment of the functioning of the immune system. In this field experiment we investigated the possible trade-offs between immune function and sexual advertisement by manipulating both mating effort and activity of immune defence in male pied flycatchers. Mating effort was increased in a non-arbitrary manner by removing females from mated males during nest building. Widowed males sustained higher haematocrit levels than control males and showed higher expression of forehead patch height, suggesting that manipulation succeeded in increasing mating effort. Males that were experimentally forced to increase mating effort had reduced humoral immune responsiveness compared with control males. In addition, experimental activation of immune defence by vaccination with novel antigens reduced the expression of male ornament dimensions. To conclude, our results indicate that causality behind the trade-off between immune function and sexual advertisement may work in both directions: sexual activity suppresses immune function but immune challenge also reduces sexual advertisement. PMID:15058434

Technology Implementation Plan: Irradiation Testing and Qualification for Nuclear Thermal Propulsion Fuel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harrison, Thomas J.; Howard, Richard H.; Rader, Jordan D.

This document is a notional technology implementation plan (TIP) for the development, testing, and qualification of a prototypic fuel element to support design and construction of a nuclear thermal propulsion (NTP) engine, specifically its pre-flight ground test. This TIP outlines a generic methodology for the progression from non-nuclear out-of-pile (OOP) testing through nuclear in-pile (IP) testing, at operational temperatures, flows, and specific powers, of an NTP fuel element in an existing test reactor. Subsequent post-irradiation examination (PIE) will occur in existing radiological facilities. Further, the methodology is intended to be nonspecific with respect to fuel types and irradiation or examinationmore » facilities. The goals of OOP and IP testing are to provide confidence in the operational performance of fuel system concepts and provide data to program leadership for system optimization and fuel down-selection. The test methodology, parameters, collected data, and analytical results from OOP, IP, and PIE will be documented for reference by the NTP operator and the appropriate regulatory and oversight authorities. Final full-scale integrated testing would be performed separately by the reactor operator as part of the preflight ground test.« less

Infrared Multiphoton Dissociation of Peptide Cations in a Dual Pressure Linear Ion Trap Mass Spectrometer

PubMed Central

Gardner, Myles W.; Smith, Suncerae I.; Ledvina, Aaron R.; Madsen, James A.; Coon, Joshua J.; Schwartz, Jae C.; Stafford, George C.; Brodbelt, Jennifer S.

2009-01-01

A dual pressure linear ion trap mass spectrometer was modified to permit infrared multiphoton dissociation (IRMPD) in each of the two cells - the first a high pressure cell operated at nominally 5 × 10-3 Torr and the second a low pressure cell operated at nominally 3 × 10-4 Torr. When IRMPD was performed in the high pressure cell, most peptide ions did not undergo significant photodissociation; however, in the low pressure cell peptide cations were efficiently dissociated with less than 25 ms of IR irradiation regardless of charge state. IRMPD of peptide cations allowed the detection of low m/z product ions including the y1 fragments and immonium ions which are not typically observed by ion trap collision induced dissociation (CID). Photodissociation efficiencies of ~100% and MS/MS (tandem mass spectrometry) efficiencies of greater than 60% were observed for both multiply and singly protonated peptides. In general, higher sequence coverage of peptides was obtained using IRMPD over CID. Further, greater than 90% of the product ion current in the IRMPD mass spectra of doubly charged peptide ions was composed of singly charged product ions compared to the CID mass spectra in which the abundances of the multiply and singly charged product ions were equally divided. Highly charged primary product ions also underwent efficient photodissociation to yield singly charged secondary product ions, thus simplifying the IRMPD product ion mass spectra. PMID:19739654

RAMAN spectroscopy imaging improves the diagnosis of papillary thyroid carcinoma

NASA Astrophysics Data System (ADS)

Rau, Julietta V.; Graziani, Valerio; Fosca, Marco; Taffon, Chiara; Rocchia, Massimiliano; Crucitti, Pierfilippo; Pozzilli, Paolo; Onetti Muda, Andrea; Caricato, Marco; Crescenzi, Anna

2016-10-01

Recent investigations strongly suggest that Raman spectroscopy (RS) can be used as a clinical tool in cancer diagnosis to improve diagnostic accuracy. In this study, we evaluated the efficiency of Raman imaging microscopy to discriminate between healthy and neoplastic thyroid tissue, by analyzing main variants of Papillary Thyroid Carcinoma (PTC), the most common type of thyroid cancer. We performed Raman imaging of large tissue areas (from 100 × 100 μm2 up to 1 × 1 mm2), collecting 38 maps containing about 9000 Raman spectra. Multivariate statistical methods, including Linear Discriminant Analysis (LDA), were applied to translate Raman spectra differences between healthy and PTC tissues into diagnostically useful information for a reliable tissue classification. Our study is the first demonstration of specific biochemical features of the PTC profile, characterized by significant presence of carotenoids with respect to the healthy tissue. Moreover, this is the first evidence of Raman spectra differentiation between classical and follicular variant of PTC, discriminated by LDA with high efficiency. The combined histological and Raman microscopy analyses allow clear-cut integration of morphological and biochemical observations, with dramatic improvement of efficiency and reliability in the differential diagnosis of neoplastic thyroid nodules, paving the way to integrative findings for tumorigenesis and novel therapeutic strategies.

Low threshold lasing of bubble-containing glass microspheres by non-whispering gallery mode excitation over a wide wavelength range

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumagai, Tsutaru, E-mail: kumagai.t.af@m.titech.ac.jp; Kishi, Tetsuo; Yano, Tetsuji

2015-03-21

Bubble-containing Nd{sup 3+}-doped tellurite glass microspheres were fabricated by localized laser heating technique to investigate their optical properties for use as microresonators. Fluorescence and excitation spectra measurements were performed by pumping with a tunable CW-Ti:Sapphire laser. The excitation spectra manifested several sharp peaks due to the conventional whispering gallery mode (WGM) when the pumping laser was irradiated to the edge part of the microsphere. However, when the excitation light was irradiated on the bubble position inside the microsphere, “non-WGM excitation” was induced, giving rise to numerous peaks at a broad wavelength range in the excitation spectra. Thus, efficient excitation wasmore » achieved over a wide wavelength range. Lasing threshold excited at the bubble position was much lower than that for the excitation at the edges of the microsphere. The lowest value of the laser threshold was 34 μW for a 4 μm sphere containing a 0.5 μm bubble. Efficiency of the excitation at the bubble position with broadband light was calculated to be 5 times higher than that for the edge of the microsphere. The bubble-containing microsphere enables efficient utilization of broadband light excitation from light-emitting diodes and solar light.« less