Photovoltaic tests and applications project

NASA Technical Reports Server (NTRS)

1978-01-01

The activities and accomplishments of the Photovoltaic Tests and Applications Project during the period April 1976 through June 1977 are summarized. Results of efforts to identify potential near-term photovoltaic applications and users are discussed, including the outcome of an extensive survey of Federal government agencies. The status of application experiments is presented. Various general engineering efforts are reported, including the design and construction of a photovoltaic Systems Test Facility. Efforts to develop a high efficiency 10 kVA self-commutated inverter and controller specifically designed for photovoltaic systems are also discussed. The results of a wide variety of activities in the area of photovoltaic measurements and standards are related. Documents generated by the Project during the reporting period are listed in an Appendix.

The Perils of Prototyping.

ERIC Educational Resources Information Center

Lowry, Christina; Little, Robert

1985-01-01

The benefits of prototyping as a basis for system design include better specifications, earlier discovery of omissions and extensions, and the likelihood of salvaging much of the effort expended on the prototype. Risks and methods of prototyping during rapid systems development are also noted. (Author/MLW)

Changes over Time in the Secondary School Experiences of Students with Disabilities. A Report of Findings from the National Longitudinal Transition Study (NLTS) and the National Longitudinal Transition Study-2 (NLTS2)

ERIC Educational Resources Information Center

Wagner, Mary; Newman, Lynn; Cameto, Renee

2004-01-01

Background: Since the early 1980s there have been extensive federal, state, and local efforts to improve schools for all students, including broad policy initiatives intended to change the school experiences of students with disabilities. These efforts have had significant impacts on policy and practice at all levels of the education system,…

Year of the Family.

ERIC Educational Resources Information Center

California Agriculture, 1994

1994-01-01

This special issue focuses on problems and challenges confronting the California family and on research and extension efforts to provide at least partial answers. Research briefs by staff include "Challenges Confront the California Family" (state trends in poverty, divorce, single-parent families, child abuse, delinquency, teen births,…

Aggregate freeze-thaw testing and d-cracking field performance : 30 years later : [summary].

DOT National Transportation Integrated Search

2014-09-01

Premature deterioration of concrete pavement due to D-cracking has been a problem in : Kansas since the 1930s. The Kansas Department of Transportation (KDOT) has made : significant efforts, including five extensive studies into the phenomenon of D-Cr...

Extension of TVCAI Project to Include Demonstration of Intelligent Videodisc System. Hardware, Software, and Courseware Implementation Component. Final Report.

ERIC Educational Resources Information Center

Brandt, Richard C.; Knapp, Barbara H.

This project, stemming from work started under the National Science Foundation grant "Development of a Television Computer Assisted Instruction (TVCAI) System" SER-7806412, called for the transfer to videodisc of some of the videotape materials developed under the grant. Three efforts were included in the proposal: design and development…

Digital processing of the Mariner 10 images of Venus and Mercury

NASA Technical Reports Server (NTRS)

Soha, J. M.; Lynn, D. J.; Mosher, J. A.; Elliot, D. A.

1977-01-01

An extensive effort was devoted to the digital processing of the Mariner 10 images of Venus and Mercury at the Image Processing Laboratory of the Jet Propulsion Laboratory. This effort was designed to optimize the display of the considerable quantity of information contained in the images. Several image restoration, enhancement, and transformation procedures were applied; examples of these techniques are included. A particular task was the construction of large mosaics which characterize the surface of Mercury and the atmospheric structure of Venus.

The Effect of Failing to Recapitalize the B-52H Defensive Avionics System on Future Operations

DTIC Science & Technology

2009-04-01

reactive jamming, compensation for wing flexing to prevent wire chaffing and ensuring the necessary degree of cooling is available to extend LRU life ...repair parts. Parts of this system including the 6-gun CRT, referenced earlier, were replaced with a commercial off-the- shelf item built by Condor...This effort will provide a small extension to the service life of the existing BWOs. There is also an effort underway to replace the BWOs with

7 CFR 3430.36 - Procedures to minimize or eliminate duplication of effort.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE COMPETITIVE AND... may implement appropriate business processes to minimize or eliminate the awarding of CSREES Federal... awards made by other Federal agencies. Business processes may include the review of the Current and...

Coordination and collaboration to document the global cotton germplasm resources

USDA-ARS?s Scientific Manuscript database

Coordinated efforts to collect and maintain cotton genetic resources have increased over the last 100 years to insure the worldwide economic value of cotton fiber and cotton byproducts. The classified genetic resources of cotton are extensive and include five tetraploid species in the primary gene ...

Liquids and homemade explosive detection

NASA Astrophysics Data System (ADS)

Ellenbogen, Michael; Bijjani, Richard

2009-05-01

Excerpt from the US Transportation Security Agency website: "The ban on liquids, aerosols and gels was implemented on August 10 after a terrorist plot was foiled. Since then, experts from around the government, including the FBI and our national labs have analyzed the information we now have and have conducted extensive explosives testing to get a better understanding of this specific threat." In order to lift the ban and ease the burden on the flying public, Reveal began an extensive effort in close collaboration with the US and several other governments to help identify these threats. This effort resulted in the successful development and testing of an automated explosive detection system capable of resolving these threats with a high probability of detection and a low false alarm rate. We will present here some of the methodology and approach we took to address this problem.

Increasing Understanding of Public Problems and Policies, 1995.

ERIC Educational Resources Information Center

Halbrook, Steve A., Ed.; Merry, Carroll E., Ed.

This document contains abstracts and the complete texts of 19 papers that were presented at a conference held to improve the policy education efforts of extension workers responsible for public affairs programs. The following papers are included: "Microwave Society and Crock-Pot Government" (Bill Graves); "Citizen Participation,…

The PIE Institute Project: Final Evaluation Report

ERIC Educational Resources Information Center

St. John, Mark; Carroll, Becky; Helms, Jen; Smith, Anita

2008-01-01

The Playful Invention and Exploration (PIE) Institute project was funded in 2005 by the National Science Foundation (NSF). For the past three years, Inverness Research has served as the external evaluator for the PIE project. The authors' evaluation efforts have included extensive observation and documentation of PIE project activities; ongoing…

48 CFR 1352.271-72 - Additional Item Requirements (AIR)-growth work

Code of Federal Regulations, 2014 CFR

2014-10-01

... Production Schedule. The ordering of any portion of the AIR quantities does not in itself warrant an extension to the original contract completion date; however, for planning purposes, the Government... cover the entire effort and shall be burdened to include: (1) Direct production labor hour functions...

48 CFR 1352.271-72 - Additional Item Requirements (AIR)-growth work

Code of Federal Regulations, 2013 CFR

2013-10-01

... Production Schedule. The ordering of any portion of the AIR quantities does not in itself warrant an extension to the original contract completion date; however, for planning purposes, the Government... cover the entire effort and shall be burdened to include: (1) Direct production labor hour functions...

48 CFR 1352.271-72 - Additional Item Requirements (AIR)-growth work

Code of Federal Regulations, 2012 CFR

2012-10-01

... Production Schedule. The ordering of any portion of the AIR quantities does not in itself warrant an extension to the original contract completion date; however, for planning purposes, the Government... cover the entire effort and shall be burdened to include: (1) Direct production labor hour functions...

The College Fact Book: Academic Year 2000-2001.

ERIC Educational Resources Information Center

El Centro Coll., Dallas, TX.

This comprehensive fact book is part of the institutional effectiveness effort at El Centro College in Texas. It provides extensive information on students, graduation, performance measures, continuing education, faculty, and finances. Report highlights (for fall 2000, unless noted otherwise) include: (1) unduplicated headcount was 4,227; (2)…

Perceptions and Resilience in Underrepresented Students' Pathways to College

ERIC Educational Resources Information Center

Perez-Felkner, Lara

2015-01-01

Background/Context: Schools have attempted to address stratification in black and Latino students' access to higher education through extensive reform initiatives, including those focused on social supports. A crucial focus has been missing from these efforts, essential to improving the effectiveness of support mechanisms and understanding why…

The Canadian effort to prevent and control hypertension: can other countries adopt Canadian strategies?

PubMed

Campbell, Norm R C; Sheldon, Tobe

2010-07-01

To indicate the key elements of current Canadian programs to treat and control hypertension. In the early 1990s Canada had a hypertension treatment and control rate of 13%. A Canadian strategy to prevent and control hypertension was developed and a coalition of national organizations and volunteers formed to develop increasingly extensive programs. The Canadian effort was largely based on annually updated hypertension management recommendations, an integrated and extensive hypertension knowledge translation program and an increasingly comprehensive outcomes assessment program. After the start of the annual process in 1999, there were very large increases in diagnosis and hypertension treatment coupled with dropping rates of cardiovascular disease. More recent initiatives include an extensive education program for the public and people with hypertension, a program to reduce dietary salt and a funded leadership position. The treatment and control rate increased to 66% when last assessed (2007-2009). The study describes important aspects of the Canadian hypertension management programs to aid those wishing to develop similar programs. Many of the programs could be fully or partially implemented by other countries.

Integrated modeling of protein-coding genes in the Manduca sexta genome using RNA-Seq data from the biochemical model insect

PubMed Central

Cao, Xiaolong; Jiang, Haobo

2015-01-01

The genome sequence of Manduca sexta was recently determined using 454 technology. Cufflinks and MAKER2 were used to establish gene models in the genome assembly based on the RNA-Seq data and other species' sequences. Aided by the extensive RNA-Seq data from 50 tissue samples at various life stages, annotators over the world (including the present authors) have manually confirmed and improved a small percentage of the models after spending months of effort. While such collaborative efforts are highly commendable, many of the predicted genes still have problems which may hamper future research on this insect species. As a biochemical model representing lepidopteran pests, M. sexta has been used extensively to study insect physiological processes for over five decades. In this work, we assembled Manduca datasets Cufflinks 3.0, Trinity 4.0, and Oases 4.0 to assist the manual annotation efforts and development of Official Gene Set (OGS) 2.0. To further improve annotation quality, we developed methods to evaluate gene models in the MAKER2, Cufflinks, Oases and Trinity assemblies and selected the best ones to constitute MCOT 1.0 after thorough crosschecking. MCOT 1.0 has 18,089 genes encoding 31,666 proteins: 32.8% match OGS 2.0 models perfectly or near perfectly, 11,747 differ considerably, and 29.5% are absent in OGS 2.0. Future automation of this process is anticipated to greatly reduce human efforts in generating comprehensive, reliable models of structural genes in other genome projects where extensive RNA-Seq data are available. PMID:25612938

Robotics-Centered Outreach Activities: An Integrated Approach

ERIC Educational Resources Information Center

Ruiz-del-Solar, Javier

2010-01-01

Nowadays, universities are making extensive efforts to attract prospective students to the fields of electrical, electronic, and computer engineering. Thus, outreach is becoming increasingly important, and activities with schoolchildren are being extensively carried out as part of this effort. In this context, robotics is a very attractive and…

General Anisotropy Identification of Paperboard with Virtual Fields Method

Treesearch

J.M. Considine; F. Pierron; K.T. Turner; D.W. Vahey

2014-01-01

This work extends previous efforts in plate bending of Virtual Fields Method (VFM) parameter identification to include a general 2-D anisotropicmaterial. Such an extension was needed for instances in which material principal directions are unknown or when specimen orientation is not aligned with material principal directions. A new fixture with a multiaxial force...

Evaluation of wildlife crossing structures and fencing on US Highway 93 Evaro to Polson Phase I : preconstruction data collection and finalization of evaluation plan : final report.

DOT National Transportation Integrated Search

2006-11-01

The US 93 reconstruction project on the Flathead Indian Reservation in northwest Montana represents one of the most extensive wildlife-sensitive highway design efforts to occur in the continental United States. The reconstruction will include install...

41 CFR 60-3.14 - Technical standards for validity studies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... likely to affect validity differences; or that these factors are included in the design of the study and... construct validity is both an extensive and arduous effort involving a series of research studies, which... validity studies. 60-3.14 Section 60-3.14 Public Contracts and Property Management Other Provisions...

41 CFR 60-3.14 - Technical standards for validity studies.

Code of Federal Regulations, 2013 CFR

2013-07-01

... likely to affect validity differences; or that these factors are included in the design of the study and... construct validity is both an extensive and arduous effort involving a series of research studies, which... validity studies. 60-3.14 Section 60-3.14 Public Contracts and Property Management Other Provisions...

41 CFR 60-3.14 - Technical standards for validity studies.

Code of Federal Regulations, 2014 CFR

2014-07-01

... likely to affect validity differences; or that these factors are included in the design of the study and... construct validity is both an extensive and arduous effort involving a series of research studies, which... validity studies. 60-3.14 Section 60-3.14 Public Contracts and Property Management Other Provisions...

41 CFR 60-3.14 - Technical standards for validity studies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... likely to affect validity differences; or that these factors are included in the design of the study and... construct validity is both an extensive and arduous effort involving a series of research studies, which... validity studies. 60-3.14 Section 60-3.14 Public Contracts and Property Management Other Provisions...

41 CFR 60-3.14 - Technical standards for validity studies.

Code of Federal Regulations, 2012 CFR

2012-07-01

... likely to affect validity differences; or that these factors are included in the design of the study and... construct validity is both an extensive and arduous effort involving a series of research studies, which... validity studies. 60-3.14 Section 60-3.14 Public Contracts and Property Management Other Provisions...

Flexible Rover Architecture for Science Instrument Integration and Testing

NASA Technical Reports Server (NTRS)

Bualat, Maria G.; Kobayashi, Linda; Lee, Susan Y.; Park, Eric

2006-01-01

At NASA Ames Research Center, the Intelligent Robotics Group (IRG) fields the K9 and K10 class rovers. Both use a mobile robot hardware architecture designed for extensibility and reconfigurability that allows for rapid changes in instrumentation and provides a high degree of modularity. Over the past ssveral years, we have worked with instrument developers at NASA centers, universities, and national laboratories to integrate or partially integrate their instruments onboard the K9 and K10 rovers. Early efforts required considerable interaction to work through integration issues such as power, data protocol and mechanical mounting. These interactions informed the design of our current avionics architecture, and have simplified more recent integration projects. In this paper, we will describe the IRG extensible avionics and software architecture and the effect it has had on our recent instrument integration efforts, including integration of four Mars Instrument Development Program devices.

Airborne Measurements of Formaldehyde Employing a Tunable Diode Laser Absorption Spectrometer During TRACE-P

NASA Technical Reports Server (NTRS)

Fried, Alan; Drummond, James

2003-01-01

This final report summarizes the progress achieved over the entire 3-year proposal period including two extensions spanning 1 year. These activities include: 1) Preparation for and participation in the NASA 2001 TRACE-P campaign using our airborne tunable diode laser system to acquire measurements of formaldehyde (CH2O); 2) Comprehensive data analysis and data submittal to the NASA archive; 3) Follow up data interpretation working with NASA modelers to place our ambient CH2O measurements into a broader photochemical context; 4) Publication of numerous JGR papers using this data; 5) Extensive follow up laboratory tests on the selectivity and efficiency of our CH20 scrubbing system; and 6) An extensive follow up effort to assess and study the mechanical stability of our entire optical system, particularly the multipass absorption cell, with aircraft changes in cabin pressure.

Dose potential of sludge contaminated and/or TRU contaminated waste in B-25s for tornado and straight wind events

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aponte, C.I.

F and H Tank Farms generate supernate and sludge contaminated Low-Level Waste. The waste is collected, characterized, and packaged for disposal. Before the waste can be disposed of, however, it must be properly characterized. Since the radionuclide distribution in typical supernate is well known, its characterization is relatively straight forward and requires minimal effort. Non-routine waste, including potentially sludge contaminated, requires much more effort to effectively characterize. The radionuclide distribution must be determined. In some cases the waste can be contaminated by various sludge transfers with unique radionuclide distributions. In these cases, the characterization can require an extensive effort. Evenmore » after an extensive characterization effort, the container must still be prepared for shipping. Therefore a significant amount of time may elapse from the time the waste is generated until the time of disposal. During the time it is possible for a tornado or high wind scenario to occur. The purpose of this report is to determine the effect of a tornado on potential sludge contaminated waste, or Transuranic (TRU) waste in B-25s [large storage containers], to evaluate the potential impact on F and H Tank Farms, and to help establish a B-25 control program for tornado events.« less

Overview of free-piston Stirling technology at the NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Slaby, J. G.

1985-01-01

An overview of the National Aeronautics and Space Administration (NASA) Lewis Research Center (Lewis) free-piston Stirling engine activities is presented. These activities include: (1) a generic free-piston Stirling technology project being conducted to develop technologies synergistic to both space power and terrestrial heat pump applications in a cooperative, cost-shared effort with the Department of Energy (DOE/Oak Ridge National Laboratory (ONRL)), and (2) a free-piston Stirling space-power technology demonstration project as part of the SP-100 program being conducted in support of the Department of Defense (DOD), DOE, and NASA/Lewis. The generic technology effort includes extensive parametric testing of a 1 kw free-piston Stirling engine (RE-1000), development and validation of a free-piston Stirling performance computer code, and fabrication and initial testing of an hydraulic output modification for the RE-1000 engine. The space power technology effort, under SP-100, addresses the status of the 25 kWe Space Power Demonstrator Engine (SPDE) including early test results.

Upper Stage Engine Composite Nozzle Extensions

NASA Technical Reports Server (NTRS)

Valentine, Peter G.; Allen, Lee R.; Gradl, Paul R.; Greene, Sandra E.; Sullivan, Brian J.; Weller, Leslie J.; Koenig, John R.; Cuneo, Jacques C.; Thompson, James; Brown, Aaron;

Extending Cognitive Load Theory to Incorporate Working Memory Resource Depletion: Evidence from the Spacing Effect

ERIC Educational Resources Information Center

Chen, Ouhao; Castro-Alonso, Juan C.; Paas, Fred; Sweller, John

2018-01-01

Depletion of limited working memory resources may occur following extensive mental effort resulting in decreased performance compared to conditions requiring less extensive mental effort. This "depletion effect" can be incorporated into cognitive load theory that is concerned with using the properties of human cognitive architecture,…

Energy Efficient Engine (E3) combustion system component technology performance report

NASA Technical Reports Server (NTRS)

Burrus, D. L.; Chahrour, C. A.; Foltz, H. L.; Sabla, P. E.; Seto, S. P.; Taylor, J. R.

1984-01-01

The Energy Efficient Engine (E3) combustor effort was conducted as part of the overall NASA/GE E3 Program. This effort included the selection of an advanced double-annular combustion system design. The primary intent of this effort was to evolve a design that meets the stringent emissions and life goals of the E3, as well as all of the usual performance requirements of combustion systems for modern turbofan engines. Numerous detailed design studies were conducted to define the features of the combustion system design. Development test hardware was fabricated, and an extensive testing effort was undertaken to evaluate the combustion system subcomponents in order to verify and refine the design. Technology derived from this effort was incorporated into the engine combustion hardware design. The advanced engine combustion system was then evaluated in component testing to verify the design intent. What evolved from this effort was an advanced combustion system capable of satisfying all of the combustion system design objectives and requirements of the E3.

An Evaluation of the Effectiveness of Televised Locally Oriented Driver Re-Education.

ERIC Educational Resources Information Center

Hutchinson, John W.; And Others

Television, with its ability to reach large audiences, has been used extensively in driver-education efforts but its effectiveness has never been measured. The purpose of this research was to measure the effectiveness of a televised, locally oriented, candid camera type of driver reeducation program. The measures of effectiveness included a study…

The Computational Infrastructure for Geodynamics as a Community of Practice

NASA Astrophysics Data System (ADS)

Hwang, L.; Kellogg, L. H.

2016-12-01

Computational Infrastructure for Geodynamics (CIG), geodynamics.org, originated in 2005 out of community recognition that the efforts of individual or small groups of researchers to develop scientifically-sound software is impossible to sustain, duplicates effort, and makes it difficult for scientists to adopt state-of-the art computational methods that promote new discovery. As a community of practice, participants in CIG share an interest in computational modeling in geodynamics and work together on open source software to build the capacity to support complex, extensible, scalable, interoperable, reliable, and reusable software in an effort to increase the return on investment in scientific software development and increase the quality of the resulting software. The group interacts regularly to learn from each other and better their practices formally through webinar series, workshops, and tutorials and informally through listservs and hackathons. Over the past decade, we have learned that successful scientific software development requires at a minimum: collaboration between domain-expert researchers, software developers and computational scientists; clearly identified and committed lead developer(s); well-defined scientific and computational goals that are regularly evaluated and updated; well-defined benchmarks and testing throughout development; attention throughout development to usability and extensibility; understanding and evaluation of the complexity of dependent libraries; and managed user expectations through education, training, and support. CIG's code donation standards provide the basis for recently formalized best practices in software development (geodynamics.org/cig/dev/best-practices/). Best practices include use of version control; widely used, open source software libraries; extensive test suites; portable configuration and build systems; extensive documentation internal and external to the code; and structured, human readable input formats.

Integrated modeling of protein-coding genes in the Manduca sexta genome using RNA-Seq data from the biochemical model insect.

PubMed

Cao, Xiaolong; Jiang, Haobo

2015-07-01

The genome sequence of Manduca sexta was recently determined using 454 technology. Cufflinks and MAKER2 were used to establish gene models in the genome assembly based on the RNA-Seq data and other species' sequences. Aided by the extensive RNA-Seq data from 50 tissue samples at various life stages, annotators over the world (including the present authors) have manually confirmed and improved a small percentage of the models after spending months of effort. While such collaborative efforts are highly commendable, many of the predicted genes still have problems which may hamper future research on this insect species. As a biochemical model representing lepidopteran pests, M. sexta has been used extensively to study insect physiological processes for over five decades. In this work, we assembled Manduca datasets Cufflinks 3.0, Trinity 4.0, and Oases 4.0 to assist the manual annotation efforts and development of Official Gene Set (OGS) 2.0. To further improve annotation quality, we developed methods to evaluate gene models in the MAKER2, Cufflinks, Oases and Trinity assemblies and selected the best ones to constitute MCOT 1.0 after thorough crosschecking. MCOT 1.0 has 18,089 genes encoding 31,666 proteins: 32.8% match OGS 2.0 models perfectly or near perfectly, 11,747 differ considerably, and 29.5% are absent in OGS 2.0. Future automation of this process is anticipated to greatly reduce human efforts in generating comprehensive, reliable models of structural genes in other genome projects where extensive RNA-Seq data are available. Copyright © 2015 Elsevier Ltd. All rights reserved.

Agricultural Extension: Farm Extension Services in Australia, Britain and the United States.

ERIC Educational Resources Information Center

Williams, Donald B.

By analyzing the scope and structure of agricultural extension services in Australia, Great Britain, and the United States, this work attempts to set guidelines for measuring progress and guiding extension efforts. Extension training, agricultural policy, and activities of national, international, state, and provincial bodies are examined. The…

The application of SMA spring actuators to a lightweight modular compliant surface bioinspired robot

NASA Astrophysics Data System (ADS)

Stone, David L.; Cranney, John; Liang, Robert; Taya, Minoru

2004-07-01

The DARPA Sponsored Compliant Surface Robotics (CSR) program pursues development of a high mobility, lightweight, modular, morph-able robot for military forces in the field and for other industrial uses. The USTLAB and University of Washington Center for Intelligent Materials and Systems (CIMS) effort builds on USTLAB proof of concept feasibility studies and demonstration of a 4, 6, or 8 wheeled modular vehicle with articulated leg-wheel assemblies. A collaborative effort between USTLAB and UW-CIMS explored the application of Shape Memory Alloy Nickel Titanium Alloy springs to a leg extension actuator capable of actuating with 4.5 Newton force over a 50 mm stroke. At the completion of Phase II, we have completed mechanical and electronics engineering design and achieved conventional actuation which currently enable active articulation, enabling autonomous reconfiguration for a wide variety of terrains, including upside down operations (in case of flip over), have developed a leg extension actuator demonstration model, and we have positioned our team to pursue a small vehicle with leg extension actuators in follow on work. The CSR vehicle's modular spider-like configuration facilitates adaptation to many uses and compliance over rugged terrain. The developmental process, actuator and vehicle characteristics will be discussed.

No Novice Teacher Left Behind: Guiding Novice Teachers to Improve Decision-Making through Structured Questioning

ERIC Educational Resources Information Center

Green, Kitty

2006-01-01

For many novice teachers, the first solo effort in the classroom is a "sink or swim" experience. With good pre-service preparation that includes extensive field experience, the beginning teacher may feel more confident, but even those with the most confidence still find the complexities of decision-making bewildering. For those novices who are…

A workshop on medical ethics at the College of Medicine, Lagos University.

PubMed

Olukoya, A A

1984-12-01

As part of an effort to improve the teaching of medical ethics in the College of Medicine, Lagos University two-day workshops were organised. Participants included people from various walks of life, for example politicians, lawyers, doctors, and patients. The workshops were quite successful, and have led to more extensive teaching of medical ethics in the college.

A National Perspective on the Current Evaluation Activities in Extension

ERIC Educational Resources Information Center

Lamm, Alexa J.; Israel, Glenn D.; Diehl, David

2013-01-01

In order to enhance Extension evaluation efforts it is important to understand current practices. The study reported here researched the evaluation behaviors of county-based Extension professionals. Extension professionals from eight states (n = 1,173) responded to a survey regarding their evaluation data collection, analysis, and reporting…

Workshop on the Development of an Experimental Global Drought Information System (GDIS): Overview of Workshop Goals

NASA Technical Reports Server (NTRS)

Schubert, Siegfried

2012-01-01

Among the key recommendations of a recent WCRP Workshop on Drought Predictability and Prediction in a Changing Climate is the development of an experimental global drought information system (GDIS). The timeliness of such an effort is evidenced by the wide aITay of relevant ongoing national and international (as well as regional and continental scale) efforts to provide drought information, including the US and North American drought monitors, and various integrating activities such as GEO and the Global Drought Portal. The workshop will review current capabilities and needs, and focus on the steps necessary to develop a GDIS that will build upon the extensive worldwide investments that have already been made in developing drought monitoring (including new space-based observations), drought risk management, and climate prediction capahilities.

Health information technology needs help from primary care researchers.

PubMed

Krist, Alex H; Green, Lee A; Phillips, Robert L; Beasley, John W; DeVoe, Jennifer E; Klinkman, Michael S; Hughes, John; Puro, Jon; Fox, Chester H; Burdick, Tim

2015-01-01

While health information technology (HIT) efforts are beginning to yield measurable clinical benefits, more is needed to meet the needs of patients and clinicians. Primary care researchers are uniquely positioned to inform the evidence-based design and use of technology. Research strategies to ensure success include engaging patient and clinician stakeholders, working with existing practice-based research networks, and using established methods from other fields such as human factors engineering and implementation science. Policies are needed to help support primary care researchers in evaluating and implementing HIT into everyday practice, including expanded research funding, strengthened partnerships with vendors, open access to information systems, and support for the Primary Care Extension Program. Through these efforts, the goal of improved outcomes through HIT can be achieved. © Copyright 2015 by the American Board of Family Medicine.

Systematic approach to understanding the pathogenesis of systemic sclerosis.

PubMed

Zuo, Xiaoxia; Zhang, Lihua; Luo, Hui; Li, Yisha; Zhu, Honglin

2017-10-01

Systemic sclerosis (SSc) is a complex heterogeneous autoimmune disease. Progressive organ fibrosis is a major contributor to SSc mortality. Despite extensive efforts, the underlying mechanism of SSc remains unclear. Efforts to understand the pathogenesis of SSc have included genomics, epigenetics, transcriptomic, proteomic and metabolomic studies in the last decade. This review focuses on recent studies in SSc research based on multi-omics. The combination of these technologies can help us understand the pathogenesis of SSc. This review aims to provide important information for disease identification, therapeutic targets and potential biomarkers. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Lessons Learned on the Road to a Smoke-Free Italy

PubMed Central

Croghan, Ivana; Muggli, Monique; Zaga, Vincenzo; Lockhart, Nikki; Ebbert, Jon; Mangiaracina, Giacomo; Hurt, Richard

2014-01-01

In the face of strong and protracted opposition by the Tobacco Industry (TI) and its allies, Italy’s national smoke-free legislation came into force in 2005 prohibiting smoking in all indoor public places and workplaces including offices, bars, and restaurants. Using internal TI documents made public through US litigation, we reveal the industry’s nearly 40-year effort to influence health policy related to secondhand smoke, including attempts to block Italy’s national smoke-free legislation. Strategies included manipulating hospitality groups and establishing front organizations, manipulating journalists and media, and manipulating the science and direct lobbying against smoking restrictions. The TI’s extensive plan to thwart smoke-free efforts in Italy can be used to inform other countries about the industry’s tactics and Italy’s experience in overcoming them by ultimately implementing a comprehensive workplace smoke-free law. PMID:21770229

Breckinridge Project, initial effort. Report XI, Volume V. Critical review of the design basis. [Critical review

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1982-01-01

Report XI, Technical Audit, is a compendium of research material used during the Initial Effort in making engineering comparisons and decisions. Volumes 4 and 5 of Report XI present those studies which provide a Critical Review of the Design Basis. The Critical Review Report, prepared by Intercontinental Econergy Associates, Inc., summarizes findings from an extensive review of the data base for the H-Coal process design. Volume 4 presents this review and assessment, and includes supporting material; specifically, Design Data Tabulation (Appendix A), Process Flow Sheets (Appendix B), and References (Appendix C). Volume 5 is a continuation of the references ofmore » Appendix C. Studies of a proprietary nature are noted and referenced, but are not included in these volumes. They are included in the Limited Access versions of these reports and may be reviewed by properly cleared personnel in the offices of Ashland Synthetic Fuels, Inc.« less

Using XML and Java for Astronomical Instrument Control

NASA Astrophysics Data System (ADS)

Koons, L.; Ames, T.; Evans, R.; Warsaw, C.; Sall, K.

1999-12-01

Traditionally, instrument command and control systems have been highly specialized, consisting mostly of custom code that is difficult to develop, maintain, and extend. Such solutions are initially very costly and are inflexible to subsequent engineering change requests. Instrument description is too tightly coupled with details of implementation. NASA/Goddard Space Flight Center and AppNet, Inc. are developing a very general and highly extensible framework that applies to virtually any kind of instrument that can be controlled by a computer (e.g., telescopes, microscopes and printers). A key aspect of the object-oriented architecture, implemented in Java, involves software that is driven by an instrument description. The Astronomical Instrument Markup Language (AIML) is a domain-specific implementation of the more generalized Instrument Markup Language (IML). The software architecture combines the platform-independent processing capabilities of Java with the vendor-independent data description syntax of Extensible Markup Language (XML), a human-readable and machine-understandable way to describe structured data. IML is used to describe command sets (including parameters, datatypes, and constraints) and their associated formats, telemetry, and communication mechanisms. The software uses this description to present graphical user interfaces to control and monitor the instrument. Recent efforts have extended to command procedures (scripting) and representation of data pipeline inputs, outputs, and connections. Near future efforts are likely to include an XML description of data visualizations, as well as the potential use of XSL (Extensible Stylesheet Language) to permit astronomers to customize the user interface on several levels: per user, instrument, subsystem, or observatory-wide. Our initial prototyping effort was targeted for HAWC (High-resolution Airborne Wideband Camera), a first-light instrument of SOFIA (the Stratospheric Observatory for Infrared Astronomy). A production-level application of this technology is for one of the three candidate detectors of SPIRE (Spectral and Photometric Imaging REceiver), a focal plane instrument proposed for the European Space Agency's Far Infrared Space Telescope. The detectors are being developed by the Infrared Astrophysics Branch of NASA/GSFC.

Final Progress Report for Ionospheric Dusty Plasma In the Laboratory [Smokey Plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robertson, Scott

2010-07-31

“Ionospheric Dusty Plasma in the Laboratory” is a research project with the purpose of finding and reproducing the characteristics of plasma in the polar mesosphere that is unusually cold (down to 140 K) and contains nanometer-sized dust particles. This final progress report summarizes results from four years of effort that include a final year with a no-cost extension.

An Analysis of the Priority Needs of Cooperative Extension at the County Level

ERIC Educational Resources Information Center

Harder, Amy; Lamm, Alexa; Strong, Robert

2009-01-01

Cooperative Extension's role as a relevant provider of nonformal education is dependent upon its ability to improve and adjust in response to internal and external pressures. Periodically conducting needs assessments focused on the Extension organization can aid in Extension's efforts to deliver quality educational programs by pinpointing priority…

Utilizing Evaluation To Develop a Marketing Strategy in the Louisiana Cooperative Extension Service.

ERIC Educational Resources Information Center

Coreil, Paul D.; Verma, Satish

Marketing has become a popular strategic initiative among state extension services to meet the growing demand for program accountability. The Louisiana Cooperative Extension Service (LCES) began a formative evaluation of its marketing efforts as a step toward a comprehensive marketing plan. All extension faculty were surveyed to determine their…

Transitioning Lessons Learned and Assets of the Global Polio Eradication Initiative to Global and Regional Measles and Rubella Elimination.

PubMed

Kretsinger, Katrina; Strebel, Peter; Kezaala, Robert; Goodson, James L

2017-07-01

The Global Polio Eradication Initiative has built an extensive infrastructure with capabilities and resources that should be transitioned to measles and rubella elimination efforts. Measles continues to be a major cause of child mortality globally, and rubella continues to be the leading infectious cause of birth defects. Measles and rubella eradication is feasible and cost saving. The obvious similarities in strategies between polio elimination and measles and rubella elimination include the use of an extensive surveillance and laboratory network, outbreak preparedness and response, extensive communications and social mobilization networks, and the need for periodic supplementary immunization activities. Polio staff and resources are already connected with those of measles and rubella, and transitioning existing capabilities to measles and rubella elimination efforts allows for optimized use of resources and the best opportunity to incorporate important lessons learned from polio eradication, and polio resources are concentrated in the countries with the highest burden of measles and rubella. Measles and rubella elimination strategies rely heavily on achieving and maintaining high vaccination coverage through the routine immunization activity infrastructure, thus creating synergies with immunization systems approaches, in what is termed a "diagonal approach." © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

Carbon-Carbon Nozzle Extension Development in Support of In-Space and Upper-Stage Liquid Rocket Engines

NASA Technical Reports Server (NTRS)

Gradl, Paul R.; Valentine, Peter G.

2017-01-01

Upper stage and in-space liquid rocket engines are optimized for performance through the use of high area ratio nozzles to fully expand combustion gases to low exit pressures, increasing exhaust velocities. Due to the large size of such nozzles, and the related engine performance requirements, carbon-carbon (C-C) composite nozzle extensions are being considered to reduce weight impacts. Currently, the state-of-the-art is represented by the metallic and foreign composite nozzle extensions limited to approximately 2000 degrees F. used on the Atlas V, Delta IV, Falcon 9, and Ariane 5 launch vehicles. NASA and industry partners are working towards advancing the domestic supply chain for C-C composite nozzle extensions. These development efforts are primarily being conducted through the NASA Small Business Innovation Research (SBIR) program in addition to other low level internal research efforts. This has allowed for the initial material development and characterization, subscale hardware fabrication, and completion of hot-fire testing in relevant environments. NASA and industry partners have designed, fabricated and hot-fire tested several subscale domestically produced C-C extensions to advance the material and coatings fabrication technology for use with a variety of liquid rocket and scramjet engines. Testing at NASA's Marshall Space Flight Center (MSFC) evaluated heritage and state-of-the-art C-C materials and coatings, demonstrating the initial capabilities of the high temperature materials and their fabrication methods. This paper discusses the initial material development, design and fabrication of the subscale carbon-carbon nozzle extensions, provides an overview of the test campaign, presents results of the hot fire testing, and discusses potential follow-on development work. The follow on work includes the fabrication of ultra-high temperature materials, larger C-C nozzle extensions, material characterization, sub-element testing and hot-fire testing at larger scale.

Cooperative Extension as a Framework for Health Extension: The Michigan State University Model.

PubMed

Dwyer, Jeffrey W; Contreras, Dawn; Eschbach, Cheryl L; Tiret, Holly; Newkirk, Cathy; Carter, Erin; Cronk, Linda

2017-10-01

The Affordable Care Act charged the Agency for Healthcare Research and Quality to create the Primary Care Extension Program, but did not fund this effort. The idea to work through health extension agents to support health care delivery systems was based on the nationally known Cooperative Extension System (CES). Instead of creating new infrastructure in health care, the CES is an ideal vehicle for increasing health-related research and primary care delivery. The CES, a long-standing component of the land-grant university system, features a sustained infrastructure for providing education to communities. The Michigan State University (MSU) Model of Health Extension offers another means of developing a National Primary Care Extension Program that is replicable in part because of the presence of the CES throughout the United States. A partnership between the MSU College of Human Medicine and MSU Extension formed in 2014, emphasizing the promotion and support of human health research. The MSU Model of Health Extension includes the following strategies: building partnerships, preparing MSU Extension educators for participation in research, increasing primary care patient referrals and enrollment in health programs, and exploring innovative funding. Since the formation of the MSU Model of Health Extension, researchers and extension professionals have made 200+ connections, and grants have afforded savings in salary costs. The MSU College of Human Medicine and MSU Extension partnership can serve as a model to promote health partnerships nationwide between CES services within land-grant universities and academic health centers or community-based medical schools.

15 CFR 291.4 - National industry-specific pollution prevention and environmental compliance resource centers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING EXTENSION PARTNERSHIP; ENVIRONMENTAL PROJECTS... information, NIST manufacturing extension efforts, EPA regulation and guidance, and state requirements. The... addition, consultants providing services to those businesses, the NIST Manufacturing Extension Centers, and...

15 CFR 291.4 - National industry-specific pollution prevention and environmental compliance resource centers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING EXTENSION PARTNERSHIP; ENVIRONMENTAL PROJECTS... information, NIST manufacturing extension efforts, EPA regulation and guidance, and state requirements. The... addition, consultants providing services to those businesses, the NIST Manufacturing Extension Centers, and...

15 CFR 291.4 - National industry-specific pollution prevention and environmental compliance resource centers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... OF COMMERCE NIST EXTRAMURAL PROGRAMS MANUFACTURING EXTENSION PARTNERSHIP; ENVIRONMENTAL PROJECTS... information, NIST manufacturing extension efforts, EPA regulation and guidance, and state requirements. The... addition, consultants providing services to those businesses, the NIST Manufacturing Extension Centers, and...

Role of Occupational Therapy in Combating Human Trafficking.

PubMed

Gorman, Kathleen W; Hatkevich, Beth Ann

Human trafficking is a modern-day form of slavery that includes sex trafficking, labor trafficking, and trafficking of children. It is estimated that 35.8 million people are enslaved around the world. Because of the traumatic experiences that victims of human trafficking encounter, the needs of victims are extensive and require the services of several providers, including health care providers, for victims to transform into survivors and thrivers. Currently, the role of occupational therapy is minimal and unexplored. The profession of occupational therapy has the capacity of having a profound role in both providing client-centered care services to victims and survivors of human trafficking and partaking in preventive advocacy efforts to combat human trafficking. Further advocacy efforts are required to promote the profession of occupational therapy in combating human trafficking. Copyright © 2016 by the American Occupational Therapy Association, Inc.

An Investigation of Aerosol Measurements from the Halogen Occultation Experiment: Validation, Size Distributions, Composition, and Relation to Other Chemical Species

NASA Technical Reports Server (NTRS)

Deshler, Terry; Hervig, Mark E.

1998-01-01

The efforts envisioned within the original proposal (accepted February 1994) and the extension of this proposal (accepted February 1997) included measurement validations, the retrieval of aerosol size distributions and distribution moments, aerosol correction studies, and investigations of polar stratospheric clouds. A majority of the results from this grant have been published. The principal results from this grant are discussed.

Not the Drones You’re Looking for: Civil Drones Invading Stability Operations

DTIC Science & Technology

2016-06-01

APPROVAL The undersigned certify that this thesis meets master’s-level standards of research , argumentation, and expression...Naval War College in 2015. His career as a developmental engineer and acquisition officer has included assignments at the Air Force Research ...culmination of not only an extensive research effort, but of an academic and intellectual journey two years in the making and I would be remiss to end

The Fundamental Physical Processes Producing and Controlling Stellar Coronal/Transition Region/Chromospheric Activity and Structure

NASA Technical Reports Server (NTRS)

Ayres, T. R.; Brown, A.

2000-01-01

Our LTSA (Long Term Space Astrophysics) research has utilized current NASA and ESA spacecraft, supporting ground-based IR, radio, and sub-mm telescopes, and the extensive archives of HST (Hubble Space Telescope), IUE (International Ultraviolet Explorer), ROSAT, EUVE (Extreme Ultraviolet Explorer), and other missions. Our research effort has included observational work (with a nonnegligible groundbased component), specialized processing techniques for imaging and spectral data, and semiempirical modelling, ranging from optically thin emission measure studies to simulations of optically thick resonance lines. In our previous LTSA efforts, we have had a number of major successes, including most recently: organizing and carrying out an extensive cool star UV survey in HST cycle eight; obtaining observing time with new instruments, such as Chandra and XMM (X-ray Multi-Mirror) in their first cycles; collaborating with the Chandra GTO program and participating with the Chandra Emission Line Project on multi-wavelength observations of HR 1099 and Capella. These are the main broad-brush themes of our previous investigation: a) Where do Coronae Occur in the Hertzsprung-Russell Diagram? b) Winds of Coronal and Noncoronal Stars; c) Activity, Age, Rotation Relations; d) Atmospheric Inhomogeneities; e) Heating Mechanisms, Subcoronal Flows, and Flares; f) Development of Analysis and Modelling Tools.

Use of Demonstration Gardens in Extension: Challenges and Benefits

ERIC Educational Resources Information Center

Glen, Charlotte D.; Moore, Gary E.; Jayaratne, K. S. U.; Bradley, Lucy K.

2014-01-01

Extension agents' use of demonstration gardens was studied to determine how gardens are employed in horticultural programming, perceived benefits and challenges of using gardens for Extension programming, and desired competencies. Gardens are primarily used to enhance educational efforts by providing hands-on learning experiences. Greatest…

Energy Efficient Engine combustor test hardware detailed design report

NASA Technical Reports Server (NTRS)

Burrus, D. L.; Chahrour, C. A.; Foltz, H. L.; Sabla, P. E.; Seto, S. P.; Taylor, J. R.

1984-01-01

The Energy Efficient Engine (E3) Combustor Development effort was conducted as part of the overall NASA/GE E3 Program. This effort included the selection of an advanced double-annular combustion system design. The primary intent was to evolve a design which meets the stringent emissions and life goals of the E3 as well as all of the usual performance requirements of combustion systems for modern turbofan engines. Numerous detailed design studies were conducted to define the features of the combustion system design. Development test hardware was fabricated, and an extensive testing effort was undertaken to evaluate the combustion system subcomponents in order to verify and refine the design. Technology derived from this development effort will be incorporated into the engine combustion system hardware design. This advanced engine combustion system will then be evaluated in component testing to verify the design intent. What is evolving from this development effort is an advanced combustion system capable of satisfying all of the combustion system design objectives and requirements of the E3. Fuel nozzle, diffuser, starting, and emissions design studies are discussed.

Overview of NASA Lewis Research Center free-piston Stirling engine activities

NASA Technical Reports Server (NTRS)

Slaby, J. G.

1984-01-01

A generic free-piston Stirling technology project is being conducted to develop technologies generic to both space power and terrestrial heat pump applications in a cooperative, cost-shared effort. The generic technology effort includes extensive parametric testing of a 1 kW free-piston Stirling engine (RE-1000), development of a free-piston Stirling performance computer code, design and fabrication under contract of a hydraulic output modification for RE-1000 engine tests, and a 1000-hour endurance test, under contract, of a 3 kWe free-piston Stirling/alternator engine. A newly initiated space power technology feasibility demonstration effort addresses the capability of scaling a free-piston Stirling/alternator system to about 25 kWe; developing thermodynamic cycle efficiency or equal to 70 percent of Carnot at temperature ratios in the order of 1.5 to 2.0; achieving a power conversion unit specific weight of 6 kg/kWe; operating with noncontacting gas bearings; and dynamically balancing the system. Planned engine and component design and test efforts are described.

Surface energy fluxes in complex terrain

NASA Technical Reports Server (NTRS)

Reiter, E. R.; Sheaffer, J. D.; Bossert, J. E.

1986-01-01

The emphasis of the 1985 NASA project activity was on field measurements of wind data and heat balance data. Initiatives included a 19 station mountaintop monitoring program, testing and refining the surface flux monitoring systems and packing and shipping equipment to the People's Republic of China in preparation for the 1986 Tibet Experiment. Other work included more extensive analyses of the 1984 Gobi Desert and Rocky Mountain observations plus some preliminary analyses of the 1985 mountaintop network data. Details of our field efforts are summarized and results of our data analyses are presented.

Voluntary enhanced cocontraction of hamstring muscles during open kinetic chain leg extension exercise: its potential unloading effect on the anterior cruciate ligament.

PubMed

Biscarini, Andrea; Benvenuti, Paolo; Botti, Fabio M; Brunetti, Antonella; Brunetti, Orazio; Pettorossi, Vito E

2014-09-01

A number of research studies provide evidence that hamstring cocontraction during open kinetic chain knee extension exercises enhances tibiofemoral (TF) stability and reduces the strain on the anterior cruciate ligament. To determine the possible increase in hamstring muscle coactivation caused by a voluntary cocontraction effort during open kinetic chain leg-extension exercises, and to assess whether an intentional hamstring cocontraction can completely suppress the anterior TF shear force during these exercises. Descriptive laboratory study. Knee kinematics as well as electromyographic activity in the semitendinosus (ST), semimembranosus (SM), biceps femoris (BF), and quadriceps femoris muscles were measured in 20 healthy men during isotonic leg extension exercises with resistance (R) ranging from 10% to 80% of the 1-repetition maximum (1RM). The same exercises were also performed while the participants attempted to enhance hamstring coactivation through a voluntary cocontraction effort. The data served as input parameters for a model to calculate the shear and compressive TF forces in leg extension exercises for any set of coactivation patterns of the different hamstring muscles. For R≤ 40% 1RM, the peak coactivation levels obtained with intentional cocontraction (l) were significantly higher (P < 10(-3)) than those obtained without intentional cocontraction (l 0). For each hamstring muscle, maximum level l was reached at R = 30% 1RM, corresponding to 9.2%, 10.5%, and 24.5% maximum voluntary isometric contraction (MVIC) for the BF, ST, and SM, respectively, whereas the ratio l/l 0 reached its maximum at R = 20% 1RM and was approximately 2, 3, and 4 for the BF, SM, and ST, respectively. The voluntary enhanced coactivation level l obtained for R≤ 30% 1RM completely suppressed the anterior TF shear force developed by the quadriceps during the exercise. In leg extension exercises with resistance R≤ 40% 1RM, coactivation of the BF, SM, and ST can be significantly enhanced (up to 2, 3, and 4 times, respectively) by a voluntary hamstring cocontraction effort. The enhanced coactivation levels obtained for R≤ 30% 1RM can completely suppress the anterior TF shear force developed by the quadriceps during the exercise. This laboratory study suggests that leg extension exercise with intentional hamstring cocontraction may have the potential to be a safe and effective quadriceps-strengthening intervention in the early stages of rehabilitation programs for anterior cruciate ligament injury or reconstruction recovery. Further studies, including clinical trials, are needed to investigate the relevance of this therapeutic exercise in clinical practice. © 2014 The Author(s).

Community Leadership Development: Implications for Extension.

ERIC Educational Resources Information Center

Northeast Regional Center for Rural Development, University Park, PA.

Designed for extension personnel who are involved in community leadership (CL) programs, this publication summarizes recent national efforts that could be useful in developing and conducting CL programs, and current leadership theory and literature. Part 1 reports the results of the national survey, initiated in April 1985, of extension staff…

Planning strategies for the avoidance of pitfalls in intervention research.

PubMed

Pruitt, R H; Privette, A B

2001-08-01

With the exception of large clinical trials, few studies in nursing and other social sciences test interventions. The discipline of nursing needs to maintain a full range of research designs for continued knowledge development. Intervention research presents unique opportunities and challenges for the novice as well as the seasoned researcher. Some of these methodological challenges include the complex nature of human subjects and interventions, including many factors that interfere with the study variables. Preliminary studies often reveal challenges that may not always be predicted or reflected in research texts. These challenges may be as important as the study results for success in future research efforts. Difficulties encountered in intervention research and suggested strategies for maintaining the integrity of the study are addressed. These challenges include maintaining an adequate sample size, intervention demands, measuring variables, timing issues, and experiencing unexpected events. Strategies presented include the importance of extensive planning, minimizing subject expectations and rewarding efforts, attention to control group members, incorporating retention strategies, expanding knowledge of variables and the study population, preliminary studies as well as anticipating unexpected events. The need for enhanced communication among nurse researchers, educators and clinicians is addressed. In the current health care arena, nurse researchers must understand organizational dynamics and marketing strategies. Collaborative research efforts can increase the visibility of nursing research as well as funding opportunities.

Cooperative Extension as a Framework for Health Extension: The Michigan State University Model

PubMed Central

Dwyer, Jeffrey W.; Contreras, Dawn; Tiret, Holly; Newkirk, Cathy; Carter, Erin; Cronk, Linda

2017-01-01

Problem The Affordable Care Act charged the Agency for Healthcare Research and Quality to create the Primary Care Extension Program, but did not fund this effort. The idea to work through health extension agents to support health care delivery systems was based on the nationally known Cooperative Extension System (CES). Instead of creating new infrastructure in health care, the CES is an ideal vehicle for increasing health-related research and primary care delivery. Approach The CES, a long-standing component of the land-grant university system, features a sustained infrastructure for providing education to communities. The Michigan State University (MSU) Model of Health Extension offers another means of developing a National Primary Care Extension Program that is replicable in part because of the presence of the CES throughout the United States. A partnership between the MSU College of Human Medicine and MSU Extension formed in 2014, emphasizing the promotion and support of human health research. The MSU Model of Health Extension includes the following strategies: building partnerships, preparing MSU Extension educators for participation in research, increasing primary care patient referrals and enrollment in health programs, and exploring innovative funding. Outcomes Since the formation of the MSU Model of Health Extension, researchers and extension professionals have made 200+ connections, and grants have afforded savings in salary costs. Next Steps The MSU College of Human Medicine and MSU Extension partnership can serve as a model to promote health partnerships nationwide between CES services within land-grant universities and academic health centers or community-based medical schools. PMID:28353501

Sexual Exploitation of Children--A Problem of Unknown Magnitude. Report to the Chairman, Subcommittee on Select Education, House Committee on Education and Labor.

ERIC Educational Resources Information Center

Ahart, Gregory J.

This report contains the results of an extensive literature search by the General Accounting Office (GAO) on the subject of teenage prostitution and child pornography and federal, state and local efforts to deal with the problem. Also included are results of a survey of police departments and mayors' offices of the 22 largest U.S. cities and all…

Advances in Time-Distance Helioseismology

NASA Technical Reports Server (NTRS)

Duvall, Thomas L., Jr.; Beck, John G.; Gizon, Laurent; Kosovichev, Alexander F.; Oegerle, William (Technical Monitor)

2002-01-01

Time-distance helioseismology is a way to measure travel times between surface locations for waves traversing the solar interior. Coupling the travel with an extensive modeling effort has proven to be a powerful tool for measuring flows and other wave speed inhomogeneities in the solar interior. Problems receiving current attention include studying the time variation of the meridional circulation and torsional oscillation and active region emergence and evolution, current results on these topics will be presented.

EMPTAC (Electromagnetic Pulse Test Aircraft) user's guide

NASA Astrophysics Data System (ADS)

Cleaveland, Dale R.; Burkhard, Avery

1988-04-01

This guide was established to give test managers a way to familiarize themselves with the Air Force Weapons Laboratory's electromagnetic pulse (EMP) test aircraft program located at Kirtland Air Force Base (KAFB), New Mexico. Brief descriptions of the available EMP test facilities at KAFB are also included. This guide should give prospective customers (users) adequate information to scope the magnitude of their test effort and to accomplish general planning without extensive involvement in test execution details.

A History of Aerospace Problems, Their Solutions, Their Lessons

NASA Technical Reports Server (NTRS)

Ryan, R. S.

1996-01-01

The positive aspect of problem occurrences is the opportunity for learning and a challenge for innovation. The learning aspect is not restricted to the solution period of the problem occurrence, but can become the beacon for problem prevention on future programs. Problems/failures serve as a point of departure for scaling to new designs. To ensure that problems/failures and their solutions guide the future programs, a concerted effort has been expended to study these problems, their solutions, their derived lessons learned, and projections for future programs. This includes identification of technology thrusts, process changes, codes development, etc. However, they must not become an excuse for adding layers upon layers of standards, criteria, and requirements, but must serve as guidelines that assist instead of stifling engineers. This report is an extension of prior efforts to accomplish this task. Although these efforts only scratch the surface, it is a beginning that others must complete.

Advanced technology for reducing aircraft engine pollution

NASA Technical Reports Server (NTRS)

Jones, R. E.

1973-01-01

The proposed EPA regulations covering emissions of gas turbine engines will require extensive combustor development. The NASA is working to develop technology to meet these goals through a wide variety of combustor research programs conducted in-house, by contract, and by university grant. In-house efforts using the swirl-can modular combustor have demonstrated sizable reduction in NO emission levels. Testing to reduce idle pollutants has included the modification of duplex fuel nozzles to air-assisted nozzles and an exploration of the potential improvements possible with combustors using fuel staging and variable geometry. The Experimental Clean Combustor Program, a large contracted effort, is devoted to the testing and development of combustor concepts designed to achieve a large reduction in the levels of all emissions. This effort is planned to be conducted in three phases with the final phase to be an engine demonstration of the best reduced emission concepts.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunett, A. J.; Fanning, T. H.

The United States has extensive experience with the design, construction, and operation of sodium cooled fast reactors (SFRs) over the last six decades. Despite the closure of various facilities, the U.S. continues to dedicate research and development (R&D) efforts to the design of innovative experimental, prototype, and commercial facilities. Accordingly, in support of the rich operating history and ongoing design efforts, the U.S. has been developing and maintaining a series of tools with capabilities that envelope all facets of SFR design and safety analyses. This paper provides an overview of the current U.S. SFR analysis toolset, including codes such asmore » SAS4A/SASSYS-1, MC2-3, SE2-ANL, PERSENT, NUBOW-3D, and LIFE-METAL, as well as the higher-fidelity tools (e.g. PROTEUS) being integrated into the toolset. Current capabilities of the codes are described and key ongoing development efforts are highlighted for some codes.« less

ATTDES: An Expert System for Satellite Attitude Determination and Control. 2

NASA Technical Reports Server (NTRS)

Mackison, Donald L.; Gifford, Kevin

1996-01-01

The design, analysis, and flight operations of satellite attitude determintion and attitude control systems require extensive mathematical formulations, optimization studies, and computer simulation. This is best done by an analyst with extensive education and experience. The development of programs such as ATTDES permit the use of advanced techniques by those with less experience. Typical tasks include the mission analysis to select stabilization and damping schemes, attitude determination sensors and algorithms, and control system designs to meet program requirements. ATTDES is a system that includes all of these activities, including high fidelity orbit environment models that can be used for preliminary analysis, parameter selection, stabilization schemes, the development of estimators covariance analyses, and optimization, and can support ongoing orbit activities. The modification of existing simulations to model new configurations for these purposes can be an expensive, time consuming activity that becomes a pacing item in the development and operation of such new systems. The use of an integrated tool such as ATTDES significantly reduces the effort and time required for these tasks.

The Human Connectome Project: A data acquisition perspective

PubMed Central

Van Essen, D.C.; Ugurbil, K.; Auerbach, E.; Barch, D.; Behrens, T.E.J.; Bucholz, R.; Chang, A.; Chen, L.; Corbetta, M.; Curtiss, S.W.; Della Penna, S.; Feinberg, D.; Glasser, M.F.; Harel, N.; Heath, A.C.; Larson-Prior, L.; Marcus, D.; Michalareas, G.; Moeller, S.; Oostenveld, R.; Petersen, S.E.; Prior, F.; Schlaggar, B.L.; Smith, S.M.; Snyder, A.Z.; Xu, J.; Yacoub, E.

2012-01-01

The Human Connectome Project (HCP) is an ambitious 5-year effort to characterize brain connectivity and function and their variability in healthy adults. This review summarizes the data acquisition plans being implemented by a consortium of HCP investigators who will study a population of 1200 subjects (twins and their non-twin siblings) using multiple imaging modalities along with extensive behavioral and genetic data. The imaging modalities will include diffusion imaging (dMRI), resting-state fMRI (R-fMRI), task-evoked fMRI (T-fMRI), T1- and T2-weighted MRI for structural and myelin mapping, plus combined magnetoencephalography and electroencephalography (MEG/EEG). Given the importance of obtaining the best possible data quality, we discuss the efforts underway during the first two years of the grant (Phase I) to refine and optimize many aspects of HCP data acquisition, including a new 7T scanner, a customized 3T scanner, and improved MR pulse sequences. PMID:22366334

1890 Institutions' Extension Program and Rural Development.

ERIC Educational Resources Information Center

Brown, Adell, Jr.

The extension role of Tuskegee Institute and the 16 black land grant colleges established by the Morrill Act of 1890 has been to diffuse among the non-university citizens of America useful and practical information on agriculture, home economics, and related areas. Tuskegee's extension efforts began in 1880 and flourished under the leadership of…

Cooperative Extension Answers the Call to Action to Support Breastfeeding

ERIC Educational Resources Information Center

Brill, Michelle F.

2016-01-01

Extension has many opportunities to promote breastfeeding, one of the most highly effective preventive measures a mother can take to protect the health of her infant and herself. This article describes how and why Cooperative Extension can and should partner with federal and state efforts to promote breastfeeding. Members of Rutgers' Family and…

Multilayer Pressure Vessel Materials Testing and Analysis Phase 2

NASA Technical Reports Server (NTRS)

Popelar, Carl F.; Cardinal, Joseph W.

2014-01-01

To provide NASA with a suite of materials strength, fracture toughness and crack growth rate test results for use in remaining life calculations for the vessels described above, Southwest Research Institute® (SwRI®) was contracted in two phases to obtain relevant material property data from a representative vessel. An initial characterization of the strength, fracture and fatigue crack growth properties was performed in Phase 1. Based on the results and recommendations of Phase 1, a more extensive material property characterization effort was developed in this Phase 2 effort. This Phase 2 characterization included additional strength, fracture and fatigue crack growth of the multilayer vessel and head materials. In addition, some more limited characterization of the welds and heat affected zones (HAZs) were performed. This report

A summary of laboratory testing performed to characterize and select an elastomeric O-ring material to be used in the redesigned solid rocket motors of the space transportation system

NASA Technical Reports Server (NTRS)

Turner, J. E.

1993-01-01

An elastomeric O-ring material is used in the joints of the redesigned solid motors (RSRM's) of the National Space Transportation System (NSTS). The selection of the O-ring material used in the RSRM's was a very thorough process that included efforts by NASA's Marshall Space Flight Center and the Langley Research Center, and the Thiokol Corporation. One of the efforts performed at MSFC was an extensive in-house laboratory test regime to screen potential O-ring materials and ultimately to characterize the elastomeric material that was chosen to be used in the RSRM's. The laboratory tests performed at MSFC are summarized.

Changes over Time in the Early Postschool Outcomes of Youth with Disabilities. A Report of Findings from the National Longitudinal Transition Study (NLTS) and the National Longitudinal Transition Study-2 (NLTS2)

ERIC Educational Resources Information Center

Wagner, Mary; Newman, Lynn; Cameto, Renee; Levine, Phyllis

2005-01-01

Background: Since the early 1980s, when A Nation at Risk sounded a clear warning about the condition of American education, there have been extensive federal, state, and local efforts to improve schools for all students, including broad policy initiatives intended to change the school experiences of students with disabilities and improve their…

Wing Shaping and Gust Load Controls of Flexible Aircraft: An LPV Approach

NASA Technical Reports Server (NTRS)

Hammerton, Jared R.; Su, Weihua; Zhu, Guoming; Swei, Sean Shan-Min

2018-01-01

In the proposed paper, the optimum wing shape of a highly flexible aircraft under varying flight conditions will be controlled by a linear parameter-varying approach. The optimum shape determined under multiple objectives, including flight performance, ride quality, and control effort, will be determined as well. This work is an extension of work done previously by the authors, and updates the existing optimization and utilizes the results to generate a robust flight controller.

USGS Colorado Water Science Center bookmark

USGS Publications Warehouse

,

2016-12-05

The U.S. Geological Survey Colorado Water Science Center conducts its water-resources activities primarily in Colorado in cooperation with more than 125 different entities. These activities include extensive data-collection efforts and studies of streamflow, water quality, and groundwater to address many specific issues of concern to Colorado water-management entities and citizens. The collected data are provided in the National Water Information System, and study results are documented in reports and information served on the Internet.

Helping Hands; Giving Volunteer Leaders a Place in the Extension Program.

ERIC Educational Resources Information Center

Strow, Helen A.

The document is a guide for extension workers, to aid them in identifying and training local volunteer leaders, thereby adding a broader dimension to the extension worker's efforts and enabling him to increase by many times the number of families he is able to reach. Leadership is defined, the importance of leaders explained, and methods for…

The Role of Evaluation in Determining the Public Value of Extension

ERIC Educational Resources Information Center

Franz, Nancy; Arnold, Mary; Baughman, Sarah

2014-01-01

Extension has developed a strong evaluation culture across the system for the last 15 years. Yet measures are still limited to the private value of programs, looking at problems in a linear way and at isolated efforts. Across the country, Extension evaluators and administrators need to step up to help answer the "so what?" question about…

76 FR 45621 - Employment and Training Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-29

... DEPARTMENT OF LABOR Employment and Training Administration Comment Request for Extension of... Administration. ACTION: Notice. SUMMARY: The Department of Labor (Department), as part of its continuing effort..., the Employment and Training Administration (ETA) is soliciting comments concerning the extension of...

Disaster averted: Community resilience in the face of a catastrophic flood.

PubMed

O'Neill, H Katherine; McLean, Andrew J; Kalis, Renetta; Shultz, James M

2016-01-01

In the spring of 2009, the Fargo, North Dakota, metropolitan area had 5 days to lay millions of sandbags to avoid devastation from record flooding of the Red River of the North. The community was able to successfully mitigate the flooding and escape potentially catastrophic economic, physical, and mental health consequences. We hypothesized that Fargo flood protection efforts reflected the community resilience factors proposed by Norris, Stevens, Pfefferbaum, et al. (2008): citizen involvement in mitigation efforts, effective organizational linkages, ongoing psychosocial support, and strong civic leadership in the face of rapidly changing circumstances. This community case report utilizes an extensive review of available sources, including news reports, government documents, research articles, and personal communication. Results demonstrate that Fargo's response to the threat of catastrophic flooding was consistent with Norris et al.'s (2008) factors of community resilience. Furthermore, success in 2009 carried over into future flood prevention and response efforts, as well as a structured approach to building psychological resilience. This case study contributes to the literature on community resilience by describing a community's successful efforts to avert a potentially catastrophic disaster.

Disaster averted: Community resilience in the face of a catastrophic flood

PubMed Central

O'Neill, H. Katherine; McLean, Andrew J.; Kalis, Renetta; Shultz, James M.

2016-01-01

ABSTRACT In the spring of 2009, the Fargo, North Dakota, metropolitan area had 5 days to lay millions of sandbags to avoid devastation from record flooding of the Red River of the North. The community was able to successfully mitigate the flooding and escape potentially catastrophic economic, physical, and mental health consequences. We hypothesized that Fargo flood protection efforts reflected the community resilience factors proposed by Norris, Stevens, Pfefferbaum, et al. (2008): citizen involvement in mitigation efforts, effective organizational linkages, ongoing psychosocial support, and strong civic leadership in the face of rapidly changing circumstances. This community case report utilizes an extensive review of available sources, including news reports, government documents, research articles, and personal communication. Results demonstrate that Fargo's response to the threat of catastrophic flooding was consistent with Norris et al.'s (2008) factors of community resilience. Furthermore, success in 2009 carried over into future flood prevention and response efforts, as well as a structured approach to building psychological resilience. This case study contributes to the literature on community resilience by describing a community's successful efforts to avert a potentially catastrophic disaster. PMID:28229016

Reducing costs of managing and accessing navigation and ancillary data by relying on the extensive capabilities of NASA's spice system

NASA Technical Reports Server (NTRS)

Semenov, Boris V.; Acton, Charles H., Jr.; Bachman, Nathaniel J.; Elson, Lee S.; Wright, Edward D.

2005-01-01

The SPICE system of navigation and ancillary data possesses a number of traits that make its use in modern space missions of all types highly cost efficient. The core of the system is a software library providing API interfaces for storing and retrieving such data as trajectories, orientations, time conversions, and instrument geometry parameters. Applications used at any stage of a mission life cycle can call SPICE APIs to access this data and compute geometric quantities required for observation planning, engineering assessment and science data analysis. SPICE is implemented in three different languages, supported on 20+ computer environments, and distributed with complete source code and documentation. It includes capabilities that are extensively tested by everyday use in many active projects and are applicable to all types of space missions - flyby, orbiters, observatories, landers and rovers. While a customer's initial SPICE adaptation for the first mission or experiment requires a modest effort, this initial effort pays off because adaptation for subsequent missions/experiments is just a small fraction of the initial investment, with the majority of tools based on SPICE requiring no or very minor changes.

EXTENSION EDUCATION SYMPOSIUM: reinventing extension as a resource--what does the future hold?

PubMed

Mirando, M A; Bewley, J M; Blue, J; Amaral-Phillips, D M; Corriher, V A; Whittet, K M; Arthur, N; Patterson, D J

2012-10-01

The mission of the Cooperative Extension Service, as a component of the land-grant university system, is to disseminate new knowledge and to foster its application and use. Opportunities and challenges facing animal agriculture in the United States have changed dramatically over the past few decades and require the use of new approaches and emerging technologies that are available to extension professionals. Increased federal competitive grant funding for extension, the creation of eXtension, the development of smartphone and related electronic technologies, and the rapidly increasing popularity of social media created new opportunities for extension educators to disseminate knowledge to a variety of audiences and engage these audiences in electronic discussions. Competitive grant funding opportunities for extension efforts to advance animal agriculture became available from the USDA National Institute of Food and Agriculture (NIFA) and have increased dramatically in recent years. The majority of NIFA funding opportunities require extension efforts to be integrated with research, and NIFA encourages the use of eXtension and other cutting-edge approaches to extend research to traditional clientele and nontraditional audiences. A case study is presented to illustrate how research and extension were integrated to improve the adoption of AI by beef producers. Those in agriculture are increasingly resorting to the use of social media venues such as Facebook, YouTube, LinkedIn, and Twitter to access information required to support their enterprises. Use of these various approaches by extension educators requires appreciation of the technology and an understanding of how the target audiences access information available on social media. Technology to deliver information is changing rapidly, and Cooperative Extension Service professionals will need to continuously evaluate digital technology and social media tools to appropriately integrate them into learning and educational opportunities.

Space Applications of Automation, Robotics and Machine Intelligence Systems (ARAMIS), phase 2. Volume 2: Telepresence project applications

NASA Technical Reports Server (NTRS)

Akin, D. L.; Minsky, M. L.; Thiel, E. D.; Kurtzman, C. R.

1983-01-01

The field of telepresence is defined and overviews of those capabilities that are now available, and those that will be required to support a NASA telepresence effort are provided. Investigation of NASA' plans and goals with regard to telepresence, extensive literature search for materials relating to relevant technologies, a description of these technologies and their state of the art, and projections for advances in these technologies over the next decade are included.

Methods of extending crop signatures from one area to another

NASA Technical Reports Server (NTRS)

Minter, T. C. (Principal Investigator)

1979-01-01

Efforts to develop a technology for signature extension during LACIE phases 1 and 2 are described. A number of haze and Sun angle correction procedures were developed and tested. These included the ROOSTER and OSCAR cluster-matching algorithms and their modifications, the MLEST and UHMLE maximum likelihood estimation procedures, and the ATCOR procedure. All these algorithms were tested on simulated data and consecutive-day LANDSAT imagery. The ATCOR, OSCAR, and MLEST algorithms were also tested for their capability to geographically extend signatures using LANDSAT imagery.

Landsat 7 Solar Array Testing Experiences

NASA Technical Reports Server (NTRS)

Helfrich, Daniel

2000-01-01

This paper covers the extensive Landsat 7 solar array flight qualification testing effort. Details of the mechanical design of the solar array and its retention/release system are presented. A testing chronology is provided beginning with the onset of problems encountered at the subsystem level and carrying through the third and final powered-spacecraft ground deployment test. Design fixes and other changes are explained in the same order as they became necessary to flight-qualify the array. Some interesting lessons learned are included along with key references.

CRC Clinical Trials Management System (CTMS): An Integrated Information Management Solution for Collaborative Clinical Research

PubMed Central

Payne, Philip R.O.; Greaves, Andrew W.; Kipps, Thomas J.

2003-01-01

The Chronic Lymphocytic Leukemia (CLL) Research Consortium (CRC) consists of 9 geographically distributed sites conducting a program of research including both basic science and clinical components. To enable the CRC’s clinical research efforts, a system providing for real-time collaboration was required. CTMS provides such functionality, and demonstrates that the use of novel data modeling, web-application platforms, and management strategies provides for the deployment of an extensible, cost effective solution in such an environment. PMID:14728471

Extension of January 25, 1995 Potential to Emit Transition Policy

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Guidance on Extension of Prevention of Significant Deterioration (PSD) Permits

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

EPA Region IX Policy on PSD Permit Extensions

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

The lift-fan powered-lift aircraft concept: Lessons learned

NASA Technical Reports Server (NTRS)

Deckert, Wallace H.

1993-01-01

This is one of a series of reports on the lessons learned from past research related to lift-fan aircraft concepts. An extensive review is presented of the many lift-fan aircraft design studies conducted by both government and industry over the past 45 years. Mission applications and design integration including discussions on manifolding hot gas generators, hot gas dusting, and energy transfer control are addressed. Past lift-fan evaluations of the Avrocar are discussed. Lessons learned from these past efforts are identified.

Popular Science Writing:Why? Who? How?

NASA Astrophysics Data System (ADS)

von Baeyer, Hans Christian

1998-04-01

Why? Under the threats of anti-science, pseudo-science, and indifference to science, popularization of physics is changing from a genteel art to a necessity for survival. Science writing is one element in a campaign that includes TV, museums, lectures, school visits, etc. Who? Five percent of the total effort of every physics department should be devoted to popularization. The academic reward system should reflect this obligation. How? Hints and suggestions for effective science writing, based on extensive experience, will be presented.

Lessons learned from the SLC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phinney, N.

The SLAC Linear Collider (SLC) is the first example of an entirely new type of lepton collider. Many years of effort were required to develop the understanding and techniques needed to approach design luminosity. This paper discusses some of the key issues and problems encountered in producing a working linear collider. These include the polarized source, techniques for emittance preservation, extensive feedback systems, and refinements in beam optimization in the final focus. The SLC experience has been invaluable for testing concepts and developing designs for a future linear collider.

Revised Draft Policy on Permit Modifications and Extensions

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Range Extension Opportunities While Heating a Battery Electric Vehicle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lustbader, Jason A; Rugh, John P; Titov, Eugene V

The Kia Soul battery electric vehicle (BEV) is available with either a positive temperature coefficient (PTC) heater or an R134a heat pump (HP) with PTC heater combination (1). The HP uses both ambient air and waste heat from the motor, inverter, and on-board-charger (OBC) for its heat source. Hanon Systems, Hyundai America Technical Center, Inc. (HATCI) and the National Renewable Energy Laboratory jointly, with financial support from the U.S. Department of Energy, developed and proved-out technologies that extend the driving range of a Kia Soul BEV while maintaining thermal comfort in cold climates. Improved system configuration concepts that use thermalmore » storage and waste heat more effectively were developed and evaluated. Range extensions of 5%-22% at ambient temperatures ranging from 5 degrees C to -18 degrees C were demonstrated. This paper reviews the three-year effort, including test data of the baseline and modified vehicles, resulting range extension, and recommendations for future actions.« less

78 FR 70584 - Extension of Information Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-26

... establishes arrangements to protect the rights of affected transit employees. Federal law requires such... DEPARTMENT OF LABOR Office of Labor-Management Standards Extension of Information Collection; Comment Request ACTION: Notice. SUMMARY: The Department of Labor, as part of its continuing effort to...

Computational strategies for three-dimensional flow simulations on distributed computer systems

NASA Technical Reports Server (NTRS)

Sankar, Lakshmi N.; Weed, Richard A.

1995-01-01

This research effort is directed towards an examination of issues involved in porting large computational fluid dynamics codes in use within the industry to a distributed computing environment. This effort addresses strategies for implementing the distributed computing in a device independent fashion and load balancing. A flow solver called TEAM presently in use at Lockheed Aeronautical Systems Company was acquired to start this effort. The following tasks were completed: (1) The TEAM code was ported to a number of distributed computing platforms including a cluster of HP workstations located in the School of Aerospace Engineering at Georgia Tech; a cluster of DEC Alpha Workstations in the Graphics visualization lab located at Georgia Tech; a cluster of SGI workstations located at NASA Ames Research Center; and an IBM SP-2 system located at NASA ARC. (2) A number of communication strategies were implemented. Specifically, the manager-worker strategy and the worker-worker strategy were tested. (3) A variety of load balancing strategies were investigated. Specifically, the static load balancing, task queue balancing and the Crutchfield algorithm were coded and evaluated. (4) The classical explicit Runge-Kutta scheme in the TEAM solver was replaced with an LU implicit scheme. And (5) the implicit TEAM-PVM solver was extensively validated through studies of unsteady transonic flow over an F-5 wing, undergoing combined bending and torsional motion. These investigations are documented in extensive detail in the dissertation, 'Computational Strategies for Three-Dimensional Flow Simulations on Distributed Computing Systems', enclosed as an appendix.

Computational strategies for three-dimensional flow simulations on distributed computer systems

NASA Astrophysics Data System (ADS)

Sankar, Lakshmi N.; Weed, Richard A.

1995-08-01

This research effort is directed towards an examination of issues involved in porting large computational fluid dynamics codes in use within the industry to a distributed computing environment. This effort addresses strategies for implementing the distributed computing in a device independent fashion and load balancing. A flow solver called TEAM presently in use at Lockheed Aeronautical Systems Company was acquired to start this effort. The following tasks were completed: (1) The TEAM code was ported to a number of distributed computing platforms including a cluster of HP workstations located in the School of Aerospace Engineering at Georgia Tech; a cluster of DEC Alpha Workstations in the Graphics visualization lab located at Georgia Tech; a cluster of SGI workstations located at NASA Ames Research Center; and an IBM SP-2 system located at NASA ARC. (2) A number of communication strategies were implemented. Specifically, the manager-worker strategy and the worker-worker strategy were tested. (3) A variety of load balancing strategies were investigated. Specifically, the static load balancing, task queue balancing and the Crutchfield algorithm were coded and evaluated. (4) The classical explicit Runge-Kutta scheme in the TEAM solver was replaced with an LU implicit scheme. And (5) the implicit TEAM-PVM solver was extensively validated through studies of unsteady transonic flow over an F-5 wing, undergoing combined bending and torsional motion. These investigations are documented in extensive detail in the dissertation, 'Computational Strategies for Three-Dimensional Flow Simulations on Distributed Computing Systems', enclosed as an appendix.

Inductive knowledge acquisition experience with commercial tools for space shuttle main engine testing

NASA Technical Reports Server (NTRS)

Modesitt, Kenneth L.

1990-01-01

Since 1984, an effort has been underway at Rocketdyne, manufacturer of the Space Shuttle Main Engine (SSME), to automate much of the analysis procedure conducted after engine test firings. Previously published articles at national and international conferences have contained the context of and justification for this effort. Here, progress is reported in building the full system, including the extensions of integrating large databases with the system, known as Scotty. Inductive knowledge acquisition has proven itself to be a key factor in the success of Scotty. The combination of a powerful inductive expert system building tool (ExTran), a relational data base management system (Reliance), and software engineering principles and Computer-Assisted Software Engineering (CASE) tools makes for a practical, useful and state-of-the-art application of an expert system.

A study of the stress wave factor technique for nondestructive evaluation of composite materials

NASA Technical Reports Server (NTRS)

Sarrafzadeh-Khoee, A.; Kiernan, M. T.; Duke, J. C., Jr.; Henneke, E. G., II

1986-01-01

The acousto-ultrasonic method of nondestructive evaluation is an extremely sensitive means of assessing material response. Efforts continue to complete the understanding of this method. In order to achieve the full sensitivity of the technique, extreme care must be taken in its performance. This report provides an update of the efforts to advance the understanding of this method and to increase its application to the nondestructive evaluation of composite materials. Included are descriptions of a novel optical system that is capable of measuring in-plane and out-of-plane displacements, an IBM PC-based data acquisition system, an extensive data analysis software package, the azimuthal variation of acousto-ultrasonic behavior in graphite/epoxy laminates, and preliminary examination of processing variation in graphite-aluminum tubes.

Progress Report on Optimizing X-ray Optical Prescriptions for Wide-Field Applications

NASA Technical Reports Server (NTRS)

Elsner, R. F.; O'Dell, S. L.; Ramsey, B. D.; Weisskopf, M. C.

2011-01-01

We report on the present status of our continuing efforts to develop a method for optimizing wide-field nested x-ray telescope mirror prescriptions. Utilizing extensive Monte-Carlo ray trace simulations, we find an analytic form for the root-mean-square dispersion of rays from a Wolter I optic on the surface of a flat focal plane detector as a function of detector tilt away from the nominal focal plane and detector displacement along the optical axis. The configuration minimizing the ray dispersion from a nested array of Wolter I telescopes is found by solving a linear system of equations for tilt and individual mirror pair displacement. Finally we outline our initial efforts at expanding this method to include higher order polynomial terms in the mirror prescriptions.

The Effort Paradox: Effort Is Both Costly and Valued.

PubMed

Inzlicht, Michael; Shenhav, Amitai; Olivola, Christopher Y

2018-04-01

According to prominent models in cognitive psychology, neuroscience, and economics, effort (be it physical or mental) is costly: when given a choice, humans and non-human animals alike tend to avoid effort. Here, we suggest that the opposite is also true and review extensive evidence that effort can also add value. Not only can the same outcomes be more rewarding if we apply more (not less) effort, sometimes we select options precisely because they require effort. Given the increasing recognition of effort's role in motivation, cognitive control, and value-based decision-making, considering this neglected side of effort will not only improve formal computational models, but also provide clues about how to promote sustained mental effort across time. Copyright © 2018 Elsevier Ltd. All rights reserved.

LOW INCOME FAMILY, TRAINING NEEDS OF HOME DEMONSTRATION EXTENSION AGENTS, HOME ECONOMICS CURRICULUM CONSTRUCTION, EDUCATION 685.

ERIC Educational Resources Information Center

MANN, OPAL H.

A STUDY WAS MADE OF THE NEED FOR EXTENSION WORK WITH LOW INCOME FAMILIES IN EASTERN KENTUCKY (APPALACHIA) AND OF THE PROBLEMS AND TRAINING NEEDS OF HOME DEMONSTRATION EXTENSION AGENTS WHO WORK WITH THESE FAMILIES. THE AGENTS FELT THEY HAD A RESPONSIBILITY TO HELP LOW INCOME FAMILIES IN BUDGETING TIME, EFFORT, AND RESOURCES TO MEET MINIMUM…

Problems Impacting Extension Program Quality at the County Level: Results from an Analysis of County Program Reviews Conducted in Florida

ERIC Educational Resources Information Center

Harder, Amy; Moore, Austen; Mazurkewicz, Melissa; Benge, Matt

2013-01-01

Needs assessments are an important tool for informing organizational development efforts in Extension. The purpose of the study reported here was to identify problems faced by county units within UF/IFAS Extension during county program reviews. The findings were drawn from the reports created after five county units experienced program reviews in…

Medical and Transmission Vector Vocabulary Alignment with Schema.org

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, William P.; Chappell, Alan R.; Corley, Courtney D.

Available biomedical ontologies and knowledge bases currently lack formal and standards-based interconnections between disease, disease vector, and drug treatment vocabularies. The PNNL Medical Linked Dataset (PNNL-MLD) addresses this gap. This paper describes the PNNL-MLD, which provides a unified vocabulary and dataset of drug, disease, side effect, and vector transmission background information. Currently, the PNNL-MLD combines and curates data from the following research projects: DrugBank, DailyMed, Diseasome, DisGeNet, Wikipedia Infobox, Sider, and PharmGKB. The main outcomes of this effort are a dataset aligned to Schema.org, including a parsing framework, and extensible hooks ready for integration with selected medical ontologies. The PNNL-MLDmore » enables researchers more quickly and easily to query distinct datasets. Future extensions to the PNNL-MLD will include Traditional Chinese Medicine, broader interlinks across genetic structures, a larger thesaurus of synonyms and hypernyms, explicit coding of diseases and drugs across research systems, and incorporating vector-borne transmission vocabularies.« less

The Politics of Extension Water Programming: Determining if Affiliation Impacts Participation

ERIC Educational Resources Information Center

Owens, Courtney T.; Lamm, Alexa J.

2017-01-01

Research has found levels of engagement in environmental behaviors and participation in Extension programming around environmental issues are directly associated with political affiliation. Democrat and Independent parties encourage members to vote for stricter environmental regulations, such as water conservation efforts, while Republicans…

User interface for ground-water modeling: Arcview extension

USGS Publications Warehouse

Tsou, Ming‐shu; Whittemore, Donald O.

2001-01-01

Numerical simulation for ground-water modeling often involves handling large input and output data sets. A geographic information system (GIS) provides an integrated platform to manage, analyze, and display disparate data and can greatly facilitate modeling efforts in data compilation, model calibration, and display of model parameters and results. Furthermore, GIS can be used to generate information for decision making through spatial overlay and processing of model results. Arc View is the most widely used Windows-based GIS software that provides a robust user-friendly interface to facilitate data handling and display. An extension is an add-on program to Arc View that provides additional specialized functions. An Arc View interface for the ground-water flow and transport models MODFLOW and MT3D was built as an extension for facilitating modeling. The extension includes preprocessing of spatially distributed (point, line, and polygon) data for model input and postprocessing of model output. An object database is used for linking user dialogs and model input files. The Arc View interface utilizes the capabilities of the 3D Analyst extension. Models can be automatically calibrated through the Arc View interface by external linking to such programs as PEST. The efficient pre- and postprocessing capabilities and calibration link were demonstrated for ground-water modeling in southwest Kansas.

Calcium phosphate cements for bone engineering and their biological properties

PubMed Central

Xu, Hockin HK; Wang, Ping; Wang, Lin; Bao, Chongyun; Chen, Qianming; Weir, Michael D; Chow, Laurence C; Zhao, Liang; Zhou, Xuedong; Reynolds, Mark A

2017-01-01

Calcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their discovery in the 1980s, extensive research has been conducted to improve their properties, and emerging evidence supports their increased application in bone tissue engineering. Much effort has been made to enhance the biological performance of CPCs, including their biocompatibility, osteoconductivity, osteoinductivity, biodegradability, bioactivity, and interactions with cells. This review article focuses on the major recent developments in CPCs, including 3D printing, injectability, stem cell delivery, growth factor and drug delivery, and pre-vascularization of CPC scaffolds via co-culture and tri-culture techniques to enhance angiogenesis and osteogenesis. PMID:29354304

Regional Climate Enterprises in the South Central U.S.: Crossover Relationships to Maximize User Engagement Effectiveness

NASA Astrophysics Data System (ADS)

Langston, M. A.; Shafer, M.; Bartush, B.; Brown, D. P.

2016-12-01

Several Federal agencies have recently established regional enterprises that provide climate science and services. These include DOI's Climate Science Centers (CSCs), USDA's Regional Climate Hubs (Hubs), DOI's Landscape Conservation Cooperatives (LCCs), and NOAA's Regional Integrated Sciences and Assessments Programs (RISAs), all of which have missions that include translating climate information for various constituencies and user groups. Each of these organizations makes a unique contribution to the regional climate services landscape; however, the potential for duplication of effort is also present. To ensure that appropriate levels of programmatic coordination are taking place, these entities have developed roles and relationships that crossover between organizations. These efforts have typically not been formally codified or prescribed; rather, they have developed organically and effectively in a fashion appropriate for the regional context. In this presentation, both advantages and disadvantages of this approach are addressed via examples from the South Central U.S. Advantages include flexibility and the development of extensive, multi-disciplinary networks; disadvantages include the lack of a holistic approach to oversight and planning. Best practices and opportunities to continue strengthening cross-organizational regional efficiencies are also highlighted.

Often Difficult--But Worth It. Collaboration among Professionals.

ERIC Educational Resources Information Center

Walker, Joyce A.

1988-01-01

A joint effort between the Minnesota Extension Service and University of Minnesota School of Medicine produced a community-based research and educational program on stress, depression, and suicide prevention. The Teens in Distress program represents a successful collaborative effort and illustrates the potential problems when Extension…

Perception of Muscular Effort During Dynamic Elbow Extension in Multiple Sclerosis.

PubMed

Heller, Mario; Retzl, Irene; Kiselka, Anita; Greisberger, Andrea

2016-02-01

To investigate the perception of muscular effort in individuals with multiple sclerosis (MS) and healthy controls during dynamic contractions. Case-control study. MS day care center. Individuals with MS (n=28) and controls (n=28) (N=56). Not applicable. Perceived muscular effort during dynamic elbow extensions was rated at 9 different weight intensities (10%-90% of 1-repetition maximum) in a single-blind, randomized order using the OMNI-Resistance Exercise Scale. Muscle activity of the triceps brachii muscle (lateral head) was measured via surface electromyography and normalized to maximal voluntary excitation. According to OMNI-level ratings, significant main effects were found for the diagnostic condition (F=27.33, P<.001, η(2)=.11), indicating 0.7 (95% confidence interval [CI], 0.3-1.1) lower mean OMNI-level ratings for MS, and for the intensity level (F=46.81, P<.001, η(2)=.46), showing increased OMNI-level ratings for increased intensity levels for both groups. Furthermore, significant main effects were found for the diagnostic condition (F=16.52, P<.001, η(2)=.07), indicating 7.1% (95% CI, -8.6 to 22.8) higher maximal voluntary excitation values for MS, and for the intensity level (F=33.09, P<.001, η(2)=.36), showing higher relative muscle activities for increasing intensity levels in both groups. Similar to controls, individuals with MS were able to differentiate between different intensities of weight during dynamic elbow extensions when provided in a single-blind, randomized order. Therefore, perceived muscular effort might be considered to control resistance training intensities in individuals with MS. However, training intensity for individuals with MS should be chosen at approximately 1 OMNI level lower than recommended, at least for dynamic elbow extension exercises. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

75 FR 51487 - Division of Coal Mine Workers' Compensation; Proposed Extension of Information Collection...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-20

... DEPARTMENT OF LABOR Office of Workers' Compensation Programs Division of Coal Mine Workers' Compensation; Proposed Extension of Information Collection; Comment Request ACTION: Notice. SUMMARY: The Department of Labor, as part of its continuing effort to reduce paperwork and respondent burden, conducts a...

Informing Extension Program Development through Audience Segmentation: Targeting High Water Users

ERIC Educational Resources Information Center

Huang, Pei-wen; Lamm, Alexa J.; Dukes, Michael D.

2016-01-01

Human reliance on water has led to water issues globally. Although extension professionals have made efforts successfully to educate the general public about water conservation to enhance water resource sustainability, difficulty has been found in reaching high water users, defined as residents irrigating excessively to their landscape irrigation…

75 FR 32971 - Comment Request for Agency Information Collection Activities: Extension of a Currently Approved...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-10

... DEPARTMENT OF LABOR Comment Request for Agency Information Collection Activities: Extension of a..., Department of Labor. ACTION: 60-day notice of information collection under review: Form ETA- 9033...-0309. SUMMARY: The Department of Labor, as part of its continuing effort to reduce paperwork and...

Emergency Food Programs: Untapped Opportunities for Extension?

ERIC Educational Resources Information Center

Mobley, Amy R.

2012-01-01

This article reports results from a questionnaire that assessed the frequency and type of nutrition questions asked at emergency food programs to determine if Extension professionals need to increase direct outreach efforts. Emergency food program workers (n = 460) were recruited via mail to complete a self-administered survey. More than one-third…

Untied Efforts: The Challenges for Improved Research, Extension and Education Linkages

ERIC Educational Resources Information Center

Eneyew, Adugna

2013-01-01

Ethiopian agriculture is characterized by smallholders farming whose access to modern technology and basic education is very limited. Research, extension, education and farmers are the main pillars of agricultural knowledge systems and their effectiveness largely depends on strong linkage among each other. However, the existing…

76 FR 33766 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Extension...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration on Aging Agency Information Collection Activities; Submission for OMB Review; Comment Request; Extension of Certification of Maintenance of Effort for the Title III and Minor Revisions to the Certification of Long-Term Care Ombudsman Program...

Economic Concepts Guiding Minnesota Extension's New Regional and County Delivery Model

ERIC Educational Resources Information Center

Morse, George W.; Klein, Thomas K.

2006-01-01

In response to a state budget deficit, the University of Minnesota Extension restructured its field staff, establishing a new regional and county delivery system, shifting all supervision of field staff to campus faculty, and encouraging greater field staff specialization, program focus, and entrepreneurial efforts. Nine economic concepts and…

Microwave integrated circuits for space applications

NASA Technical Reports Server (NTRS)

Leonard, Regis F.; Romanofsky, Robert R.

1991-01-01

Monolithic microwave integrated circuits (MMIC), which incorporate all the elements of a microwave circuit on a single semiconductor substrate, offer the potential for drastic reductions in circuit weight and volume and increased reliability, all of which make many new concepts in electronic circuitry for space applications feasible, including phased array antennas. NASA has undertaken an extensive program aimed at development of MMICs for space applications. The first such circuits targeted for development were an extension of work in hybrid (discrete component) technology in support of the Advanced Communication Technology Satellite (ACTS). It focused on power amplifiers, receivers, and switches at ACTS frequencies. More recent work, however, focused on frequencies appropriate for other NASA programs and emphasizes advanced materials in an effort to enhance efficiency, power handling capability, and frequency of operation or noise figure to meet the requirements of space systems.

Designing Fault-Injection Experiments for the Reliability of Embedded Systems

NASA Technical Reports Server (NTRS)

White, Allan L.

2012-01-01

This paper considers the long-standing problem of conducting fault-injections experiments to establish the ultra-reliability of embedded systems. There have been extensive efforts in fault injection, and this paper offers a partial summary of the efforts, but these previous efforts have focused on realism and efficiency. Fault injections have been used to examine diagnostics and to test algorithms, but the literature does not contain any framework that says how to conduct fault-injection experiments to establish ultra-reliability. A solution to this problem integrates field-data, arguments-from-design, and fault-injection into a seamless whole. The solution in this paper is to derive a model reduction theorem for a class of semi-Markov models suitable for describing ultra-reliable embedded systems. The derivation shows that a tight upper bound on the probability of system failure can be obtained using only the means of system-recovery times, thus reducing the experimental effort to estimating a reasonable number of easily-observed parameters. The paper includes an example of a system subject to both permanent and transient faults. There is a discussion of integrating fault-injection with field-data and arguments-from-design.

Hazardous healthcare waste management in the Kingdom of Bahrain.

PubMed

Mohamed, L F; Ebrahim, S A; Al-Thukair, A A

2009-08-01

Hazardous healthcare waste has become an environmental concern for many developing countries including the Kingdom of Bahrain. There have been several significant obstacles facing the Kingdom in dealing with this issue including; limited documentation regarding generation, handling, management, and disposal of waste. This in turn hinders efforts to plan better healthcare waste management. In this paper, hazardous waste management status in the Kingdom has been investigated through an extensive survey carried out on selected public and private healthcare premises. Hazardous waste management practices including: waste generation, segregation, storage, collection, transportation, treatment, and disposal were determined. The results of this study along with key findings are discussed and summarized. In addition; several effective recommendations and improvements of hazardous waste management are suggested.

Hazardous healthcare waste management in the Kingdom of Bahrain

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mohamed, L.F.; Ebrahim, S.A.; Al-Thukair, A.A.

2009-08-15

Hazardous healthcare waste has become an environmental concern for many developing countries including the Kingdom of Bahrain. There have been several significant obstacles facing the Kingdom in dealing with this issue including; limited documentation regarding generation, handling, management, and disposal of waste. This in turn hinders efforts to plan better healthcare waste management. In this paper, hazardous waste management status in the Kingdom has been investigated through an extensive survey carried out on selected public and private healthcare premises. Hazardous waste management practices including: waste generation, segregation, storage, collection, transportation, treatment, and disposal were determined. The results of this studymore » along with key findings are discussed and summarized. In addition; several effective recommendations and improvements of hazardous waste management are suggested.« less

Mobile terrestrial light detection and ranging (T-LiDAR) survey of areas on Dauphin Island, Alabama, in the aftermath of Hurricane Isaac, 2012

USGS Publications Warehouse

Kimbrow, Dustin R.

2014-01-01

Topographic survey data of areas on Dauphin Island on the Alabama coast were collected using a truck-mounted mobile terrestrial light detection and ranging system. This system is composed of a high frequency laser scanner in conjunction with an inertial measurement unit and a position and orientation computer to produce highly accurate topographic datasets. A global positioning system base station was set up on a nearby benchmark and logged vertical and horizontal position information during the survey for post-processing. Survey control points were also collected throughout the study area to determine residual errors. Data were collected 5 days after Hurricane Isaac made landfall in early September 2012 to document sediment deposits prior to clean-up efforts. Three data files in ASCII text format with the extension .xyz are included in this report, and each file is named according to both the acquisition date and the relative geographic location on Dauphin Island (for example, 20120903_Central.xyz). Metadata are also included for each of the files in both Extensible Markup Language with the extension .xml and ASCII text formats. These topographic data can be used to analyze the effects of storm surge on barrier island environments and also serve as a baseline dataset for future change detection analyses.

The NASA Electric Propulsion Program

NASA Technical Reports Server (NTRS)

Callahan, Lisa Wood; Curran, Francis M.

1996-01-01

Nearly all space missions require on-board propulsion systems and these systems typically have a major impact on spacecraft mass and cost. Electric propulsion systems offer major performance advantages over conventional chemical systems for many mission functions and the NASA Office of Space Access and Technology (OSAT) supports an extensive effort to develop the technology for high-performance, on-board electric propulsion system options to enhance and enable near- and far-term US space missions. This program includes research and development efforts on electrothermal, electrostatic, and electromagnetic propulsion system technologies to cover a wide range of potential applications. To maximize expectations of technology transfer, the program emphasizes strong interaction with the user community through a variety of cooperative and contracted approaches. This paper provides an overview of the OSAT electric propulsion program with an emphasis on recent progress and future directions.

Mechanical Analysis of W78/88-1 Life Extension Program Warhead Design Options

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spencer, Nathan

2014-09-01

Life Extension Program (LEP) is a program to repair/replace components of nuclear weapons to ensure the ability to meet military requirements. The W78/88-1 LEP encompasses the modernization of two major nuclear weapon reentry systems into an interoperable warhead. Several design concepts exist to provide different options for robust safety and security themes, maximum non-nuclear commonality, and cost. Simulation is one capability used to evaluate the mechanical performance of the designs in various operational environments, plan for system and component qualification efforts, and provide insight into the survivability of the warhead in environments that are not currently testable. The simulation effortsmore » use several Sandia-developed tools through the Advanced Simulation and Computing program, including Cubit for mesh generation, the DART Model Manager, SIERRA codes running on the HPC TLCC2 platforms, DAKOTA, and ParaView. Several programmatic objectives were met using the simulation capability including: (1) providing early environmental specification estimates that may be used by component designers to understand the severity of the loads their components will need to survive, (2) providing guidance for load levels and configurations for subassembly tests intended to represent operational environments, and (3) recommending design options including modified geometry and material properties. These objectives were accomplished through regular interactions with component, system, and test engineers while using the laboratory's computational infrastructure to effectively perform ensembles of simulations. Because NNSA has decided to defer the LEP program, simulation results are being documented and models are being archived for future reference. However, some advanced and exploratory efforts will continue to mature key technologies, using the results from these and ongoing simulations for design insights, test planning, and model validation.« less

Extensive Training Is Insufficient to Produce The Work-Ethic Effect In Pigeons

PubMed Central

Vasconcelos, Marco; Urcuioli, Peter J

2009-01-01

Zentall and Singer (2007a) hypothesized that our failure to replicate the work-ethic effect in pigeons (Vasconcelos, Urcuioli, & Lionello-DeNolf, 2007) was due to insufficient overtraining following acquisition of the high- and low-effort discriminations. We tested this hypothesis using the original work-ethic procedure (Experiment 1) and one similar to that used with starlings (Experiment 2) by providing at least 60 overtraining sessions. Despite this extensive overtraining, neither experiment revealed a significant preference for stimuli obtained after high effort. Together with other findings, these data support our contention that pigeons do not reliably show a work-ethic effect. PMID:19230517

SCaN Testbed Software Development and Lessons Learned

NASA Technical Reports Server (NTRS)

Kacpura, Thomas J.; Varga, Denise M.

2012-01-01

National Aeronautics and Space Administration (NASA) has developed an on-orbit, adaptable, Software Defined Radio (SDR)Space Telecommunications Radio System (STRS)-based testbed facility to conduct a suite of experiments to advance technologies, reduce risk, and enable future mission capabilities on the International Space Station (ISS). The SCAN Testbed Project will provide NASA, industry, other Government agencies, and academic partners the opportunity to develop and field communications, navigation, and networking technologies in the laboratory and space environment based on reconfigurable, SDR platforms and the STRS Architecture.The SDRs are a new technology for NASA, and the support infrastructure they require is different from legacy, fixed function radios. SDRs offer the ability to reconfigure on-orbit communications by changing software for new waveforms and operating systems to enable new capabilities or fix any anomalies, which was not a previous option. They are not stand alone devices, but required a new approach to effectively control them and flow data. This requires extensive software to be developed to utilize the full potential of these reconfigurable platforms. The paper focuses on development, integration and testing as related to the avionics processor system, and the software required to command, control, monitor, and interact with the SDRs, as well as the other communication payload elements. An extensive effort was required to develop the flight software and meet the NASA requirements for software quality and safety. The flight avionics must be radiation tolerant, and these processors have limited capability in comparison to terrestrial counterparts. A big challenge was that there are three SDRs onboard, and interfacing with multiple SDRs simultaneously complicatesd the effort. The effort also includes ground software, which is a key element for both the command of the payload, and displaying data created by the payload. The verification of the software was an extensive effort. The challenges of specifying a suitable test matrix with reconfigurable systems that offer numerous configurations is highlighted. Since the flight system testing requires methodical, controlled testing that limits risk, a nearly identical ground system to the on-orbit flight system was required to develop the software and write verification procedures before it was installed and tested on the flight system. The development of the SCAN testbed was an accelerated effort to meet launch constraints, and this paper discusses tradeoffs made to balance needed software functionality and still maintain the schedule. Future upgrades are discussed that optimize the avionics and allow experimenters to utilize the SCAN testbed potential.

Request for Extension on PSD Permit for Indianapolis Power and Light Company

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Applicability of PSD Requirements to the Wisconsin Electric Power Company Port Washington Life Extension Project

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Aerodynamic design trends for commercial aircraft

NASA Technical Reports Server (NTRS)

Hilbig, R.; Koerner, H.

1986-01-01

Recent research on advanced-configuration commercial aircraft at DFVLR is surveyed, with a focus on aerodynamic approaches to improved performance. Topics examined include transonic wings with variable camber or shock/boundary-layer control, wings with reduced friction drag or laminarized flow, prop-fan propulsion, and unusual configurations or wing profiles. Drawings, diagrams, and graphs of predicted performance are provided, and the need for extensive development efforts using powerful computer facilities, high-speed and low-speed wind tunnels, and flight tests of models (mounted on specially designed carrier aircraft) is indicated.

Development of a Power Electronics Controller for the Advanced Stirling Radioisotope Generator

NASA Technical Reports Server (NTRS)

Leland, Douglas K.; Priest, Joel F.; Keiter, Douglas E.; Schreiber, Jeffrey G.

2008-01-01

Under a U.S. Department of Energy program for radioisotope power systems, Lockheed Martin is developing an Engineering Unit of the Advanced Stirling Radioisotope Generator (ASRG). This is an advanced version of the previously reported SRG110 generator. The ASRG uses Advanced Stirling Convertors (ASCs) developed by Sunpower Incorporated under a NASA Research Announcement contract. The ASRG makes use of a Stirling controller based on power electronics that eliminates the tuning capacitors. The power electronics controller synchronizes dual-opposed convertors and maintains a fixed frequency operating point. The controller is single-fault tolerant and uses high-frequency pulse width modulation to create the sinusoidal currents that are nearly in phase with the piston velocity, eliminating the need for large series tuning capacitors. Sunpower supports this effort through an extension of their controller development intended for other applications. Glenn Research Center (GRC) supports this effort through system dynamic modeling, analysis and test support. The ASRG design arrived at a new baseline based on a system-level trade study and extensive feedback from mission planners on the necessity of single-fault tolerance. This paper presents the baseline design with an emphasis on the power electronics controller detailed design concept that will meet space mission requirements including single fault tolerance.

Burnout among psychosocial oncologists: an application and extension of the effort–reward imbalance model

PubMed Central

Rasmussen, Victoria; Turnell, Adrienne; Butow, Phyllis; Juraskova, Ilona; Kirsten, Laura; Wiener, Lori; Patenaude, Andrea; Hoekstra-Weebers, Josette; Grassi, Luigi

2016-01-01

Objectives Burnout is a significant problem among healthcare professionals working within the oncology setting. This study aimed to investigate predictors of emotional exhaustion (EE) and depersonalisation (DP) in psychosocial oncologists, through the application of the effort–reward imbalance (ERI) model with an additional focus on the role of meaningful work in the burnout process. Methods Psychosocial oncology clinicians (n = 417) in direct patient contact who were proficient in English were recruited from 10 international psychosocial oncology societies. Participants completed an online questionnaire, which included measures of demographic and work characteristics, EE and DP subscales of the Maslach Burnout Inventory-Human Services Survey, the Short Version ERI Questionnaire and the Work and Meaning Inventory. Results Higher effort and lower reward were both significantly associated with greater EE, although not DP. The interaction of higher effort and lower reward did not predict greater EE or DP. Overcommitment predicted both EE and DP but did not moderate the impact of effort and reward on burnout. Overall, the ERI model accounted for 33% of the variance in EE. Meaningful work significantly predicted both EE and DP but accounted for only 2% more of the variance in EE above and beyond the ERI model. Conclusions The ERI was only partially supported as a useful framework for investigating burnout in psychosocial oncology professionals. Meaningful work may be a viable extension of the ERI model. Burnout among health professionals may be reduced by interventions aimed at increasing self-efficacy and changes to the supportive work environment. PMID:26239424

Minimizing Dispersion in FDTD Methods with CFL Limit Extension

NASA Astrophysics Data System (ADS)

Sun, Chen

The CFL extension in FDTD methods is receiving considerable attention in order to reduce the computational effort and save the simulation time. One of the major issues in the CFL extension methods is the increased dispersion. We formulate a decomposition of FDTD equations to study the behaviour of the dispersion. A compensation scheme to reduce the dispersion in CFL extension is constructed and proposed. We further study the CFL extension in a FDTD subgridding case, where we improve the accuracy by acting only on the FDTD equations of the fine grid. Numerical results confirm the efficiency of the proposed method for minimising dispersion.

Building Extension Partnerships with Government to Further Water Conservation Efforts

ERIC Educational Resources Information Center

McKee, Brandon; Huang, Pei-wen; Lamm, Alexa

2017-01-01

Extension, being a local, state and federally funded program has a natural partnership with government agencies at all three levels, however these partnerships could be built upon and targeted at specific audiences for greater effect if more is known about how government influences public perception. The government has recognized the need for…

What Extension Professionals Say about Teaching Health Insurance: Results from a Nationwide Survey

ERIC Educational Resources Information Center

Brown, Virginia; Koonce, Joan C.; Martin, Ken; Kiss, Elizabeth; Katras, Mary Jo; Wise, Dena

2017-01-01

The Extension Committees on Organization and Policy adopted a new Health and Wellness Framework with six priority areas. A health insurance literacy team was appointed to assess current system efforts and develop research, programs, and professional development opportunities. Survey results show that finance educators were the most likely…

Fundamental Dimensions and Essential Elements of Exemplary Local Extension Units

ERIC Educational Resources Information Center

Terry, Bryan D.; Osborne, Edward

2015-01-01

Collaborative efforts between federal, state, and local government agencies enable local Extension units to deliver a high level of educational opportunities to local citizens. These units represent land-grant institutions by delivering non-formal education that aim to address local, regional, and state concerns. The purpose of this study was to…

Enhancing Extension and Research Activities through the Use of Web GIS

ERIC Educational Resources Information Center

Estwick, Noel M.; Griffin, Richard W.; James, Annette A.; Roberson, Samuel G.

2016-01-01

There have been numerous efforts aimed at improving geographic literacy in order to address societal challenges. Extension educators can use geographic information system (GIS) technology to help their clients cultivate spatial thinking skills and solve problems. Researchers can use it to model relationships and better answer questions. A program…

Dare To Be You: A Diversion Program for First Time Juvenile Offenders.

ERIC Educational Resources Information Center

Vail, Ann; Nest, Judy

This document notes that community-based organizations such as the Cooperative Extension Service have joined the efforts to reduce juvenile delinquency through juvenile diversion programs. It then describes the "Dare to be You" program that was developed by the Colorado Cooperative Extension System. The six objectives of the program delineated in…

Extension Newsletters and Individual Counseling: Equally Effective in Changing Worksite Wellness Participants Dietary Intakes

ERIC Educational Resources Information Center

Chipman, Kristi; Litchfield, Ruth

2012-01-01

The Affordable Care Act provides impetus for Extension efforts in worksite wellness. The study reported here examined the influence of two worksite wellness interventions, newsletters and individual counseling. Surveys examined dietary and physical activity behaviors of participants pre- and post-intervention (N = 157). Descriptive statistics,…

Missouri Extension Provides Tax Assistance to Rural Families

ERIC Educational Resources Information Center

Huston, Sandra J.; Procter, Brenda

2006-01-01

Financial education is one pathway to improving the human condition. Family financial educators in University Extension programs lead in their efforts to provide individuals and families with the skills they need to manage their financial resources effectively. Offering these opportunities at a time when families have money to manage is a key…

Applying Coaching Strategies to Support Youth- and Family-Focused Extension Programming

ERIC Educational Resources Information Center

Olson, Jonathan R.; Hawkey, Kyle R.; Smith, Burgess; Perkins, Daniel F.; Borden, Lynne M.

2016-01-01

In this article, we describe how a peer-coaching model has been applied to support community-based Extension programming through the Children, Youth, and Families at Risk (CYFAR) initiative. We describe the general approaches to coaching that have been used to help with CYFAR program implementation, evaluation, and sustainability efforts; we…

Microdialysis Sampling Techniques Applied to Studies of the Foreign Body Reaction

PubMed Central

Sides, Cynthia R.; Stenken, Julie A.

2014-01-01

Implanted materials including drug delivery devices and chemical sensors undergo what is termed the foreign body reaction (FBR). Depending on the device and its intended application, the FBR can have differing consequences. An extensive scientific research effort has been devoted to elucidating the cellular and molecular mechanisms that drive the FBR. Important, yet relatively unexplored, research includes the localized tissue biochemistry and the chemical signaling events that occur throughout the FBR. This review provides an overview of the mechanisms of the FBR, describes how the FBR affects different implanted devices, and illustrates the role that microdialysis sampling can play in further elucidating the chemical communication processes that drive FBR outcomes. PMID:24269987

Time domain simulations of preliminary breakdown pulses in natural lightning.

PubMed

Carlson, B E; Liang, C; Bitzer, P; Christian, H

2015-06-16

Lightning discharge is a complicated process with relevant physical scales spanning many orders of magnitude. In an effort to understand the electrodynamics of lightning and connect physical properties of the channel to observed behavior, we construct a simulation of charge and current flow on a narrow conducting channel embedded in three-dimensional space with the time domain electric field integral equation, the method of moments, and the thin-wire approximation. The method includes approximate treatment of resistance evolution due to lightning channel heating and the corona sheath of charge surrounding the lightning channel. Focusing our attention on preliminary breakdown in natural lightning by simulating stepwise channel extension with a simplified geometry, our simulation reproduces the broad features observed in data collected with the Huntsville Alabama Marx Meter Array. Some deviations in pulse shape details are evident, suggesting future work focusing on the detailed properties of the stepping mechanism. Preliminary breakdown pulses can be reproduced by simulated channel extension Channel heating and corona sheath formation are crucial to proper pulse shape Extension processes and channel orientation significantly affect observations.

Time domain simulations of preliminary breakdown pulses in natural lightning

PubMed Central

Carlson, B E; Liang, C; Bitzer, P; Christian, H

2015-01-01

Lightning discharge is a complicated process with relevant physical scales spanning many orders of magnitude. In an effort to understand the electrodynamics of lightning and connect physical properties of the channel to observed behavior, we construct a simulation of charge and current flow on a narrow conducting channel embedded in three-dimensional space with the time domain electric field integral equation, the method of moments, and the thin-wire approximation. The method includes approximate treatment of resistance evolution due to lightning channel heating and the corona sheath of charge surrounding the lightning channel. Focusing our attention on preliminary breakdown in natural lightning by simulating stepwise channel extension with a simplified geometry, our simulation reproduces the broad features observed in data collected with the Huntsville Alabama Marx Meter Array. Some deviations in pulse shape details are evident, suggesting future work focusing on the detailed properties of the stepping mechanism. Key Points Preliminary breakdown pulses can be reproduced by simulated channel extension Channel heating and corona sheath formation are crucial to proper pulse shape Extension processes and channel orientation significantly affect observations PMID:26664815

Derrida's Right to Philosophy, Then and Now

ERIC Educational Resources Information Center

Willinsky, John

2009-01-01

In this essay, a tribute to Jacques Derrida's educational efforts at expanding access to current work in philosophy, John Willinsky examines his efforts as both a public right and an element of academic freedom that bear on the open access movement today. Willinsky covers Derrida's extension and outreach work with the Groupe de Recherches pour…

Innovative and Coordinated Solutions for the Hardwood Industry: The Hardwood Utilization Consortium

Treesearch

Philip A. Araman; Cynthia West

1996-01-01

Many varied efforts have been underway to help the hardwood industry make more effective and efficient use of the hardwood resource while meeting market needs. The efforts range from training, extension, utilization and marketing research and development, to educational activities. The activities are disjointed and unorganized and individually struggling to maintain...

Collaborative Professional Learning through Lesson Study: Identifying the Challenges of Inquiry-Based Teaching

ERIC Educational Resources Information Center

Gutierez, Sally Baricaua

2015-01-01

In the Philippines, inquiry-based teaching has been promoted and implemented together with recently instigated curriculum reforms. Serious teacher professional development efforts are being used extensively to properly orient and present the benefits of inquirybased teaching. Despite these efforts, there still exists a big gap in the effective…

Effects of Hot Streak and Phantom Cooling on Heat Transfer in a Cooled Turbine Stage Including Particulate Deposition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bons, Jeffrey; Ameri, Ali

2016-01-08

The objective of this research effort was to develop a validated computational modeling capability for the characterization of the effects of hot streaks and particulate deposition on the heat load of modern gas turbines. This was accomplished with a multi-faceted approach including analytical, experimental, and computational components. A 1-year no cost extension request was approved for this effort, so the total duration was 4 years. The research effort succeeded in its ultimate objective by leveraging extensive experimental deposition studies complemented by computational modeling. Experiments were conducted with hot streaks, vane cooling, and combinations of hot streaks with vane cooling. Thesemore » studies contributed to a significant body of corporate knowledge of deposition, in combination with particle rebound and deposition studies funded by other agencies, to provide suitable conditions for the development of a new model. The model includes the following physical phenomena: elastic deformation, plastic deformation, adhesion, and shear removal. It also incorporates material property sensitivity to temperature and tangential-normal velocity rebound cross-dependencies observed in experiments. The model is well-suited for incorporation in CFD simulations of complex gas turbine flows due to its algebraic (explicit) formulation. This report contains model predictions compared to coefficient of restitution data available in the open literature as well as deposition results from two different high temperature turbine deposition facilities. While the model comparisons with experiments are in many cases promising, several key aspects of particle deposition remain elusive. The simple phenomenological nature of the model allows for parametric dependencies to be evaluated in a straightforward manner. This effort also included the first-ever full turbine stage deposition model published in the open literature. The simulations included hot streaks and simulated vane cooling. The new deposition model was implemented into the CFD model as a wall boundary condition, with various particle sizes investigated in the simulation. Simulations utilizing a steady mixing plane formulation and an unsteady sliding mesh were conducted and the flow solution of each was validated against experimental data. Results from each of these simulations, including impact and capture distributions and efficiencies, were compared and potential reasons for differences discussed in detail. The inclusion of a large range of particle sizes allowed investigation of trends with particle size, such as increased radial migration and reduced sticking efficiency at the larger particle sizes. The unsteady simulation predicted lower sticking efficiencies on the rotor blades than the mixing plane simulation for the majority of particle sizes. This is postulated to be due to the preservation of the hot streak and cool vane wake through the vane-rotor interface (which are smeared out circumferentially in the mixing-plane simulation). The results reported here represent the successful implementation of a novel deposition model into validated vane-rotor flow solutions that include a non-uniform inlet temperature profile and simulated vane cooling.« less

Muscle coordination, activation and kinematics of world-class and elite breaststroke swimmers during submaximal and maximal efforts.

PubMed

Olstad, Bjørn Harald; Vaz, João Rocha; Zinner, Christoph; Cabri, Jan M H; Kjendlie, Per-Ludvik

2017-06-01

The aims of this study were to describe muscular activation patterns and kinematic variables during the complete stroke cycle (SC) and the different phases of breaststroke swimming at submaximal and maximal efforts. Surface electromyography (sEMG) was collected from eight muscles in nine elite swimmers; five females (age 20.3 ± 5.4 years; Fédération Internationale de Natation [FINA] points 815 ± 160) and four males (27.7 ± 7.1 years; FINA points 879 ± 151). Underwater cameras were used for 3D kinematic analysis with automatic motion tracking. The participants swam 25 m of breaststroke at 60%, 80% and 100% effort and each SC was divided into three phases: knee extension, knee extended and knee flexion. With increasing effort, the swimmers decreased their SC distance and increased their velocity and stroke rate. A decrease during the different phases was found for duration during knee extended and knee flexion, distance during knee extended and knee angle at the beginning of knee extension with increasing effort. Velocity increased for all phases. The mean activation pattern remained similar across the different effort levels, but the muscles showed longer activation periods relative to the SC and increased integrated sEMG (except trapezius) with increasing effort. The muscle activation patterns, muscular participation and kinematics assessed in this study with elite breaststroke swimmers contribute to a better understanding of the stroke and what occurs at different effort levels. This could be used as a reference for optimising breaststroke training to improve performance.

FuGEFlow: data model and markup language for flow cytometry.

PubMed

Qian, Yu; Tchuvatkina, Olga; Spidlen, Josef; Wilkinson, Peter; Gasparetto, Maura; Jones, Andrew R; Manion, Frank J; Scheuermann, Richard H; Sekaly, Rafick-Pierre; Brinkman, Ryan R

2009-06-16

Flow cytometry technology is widely used in both health care and research. The rapid expansion of flow cytometry applications has outpaced the development of data storage and analysis tools. Collaborative efforts being taken to eliminate this gap include building common vocabularies and ontologies, designing generic data models, and defining data exchange formats. The Minimum Information about a Flow Cytometry Experiment (MIFlowCyt) standard was recently adopted by the International Society for Advancement of Cytometry. This standard guides researchers on the information that should be included in peer reviewed publications, but it is insufficient for data exchange and integration between computational systems. The Functional Genomics Experiment (FuGE) formalizes common aspects of comprehensive and high throughput experiments across different biological technologies. We have extended FuGE object model to accommodate flow cytometry data and metadata. We used the MagicDraw modelling tool to design a UML model (Flow-OM) according to the FuGE extension guidelines and the AndroMDA toolkit to transform the model to a markup language (Flow-ML). We mapped each MIFlowCyt term to either an existing FuGE class or to a new FuGEFlow class. The development environment was validated by comparing the official FuGE XSD to the schema we generated from the FuGE object model using our configuration. After the Flow-OM model was completed, the final version of the Flow-ML was generated and validated against an example MIFlowCyt compliant experiment description. The extension of FuGE for flow cytometry has resulted in a generic FuGE-compliant data model (FuGEFlow), which accommodates and links together all information required by MIFlowCyt. The FuGEFlow model can be used to build software and databases using FuGE software toolkits to facilitate automated exchange and manipulation of potentially large flow cytometry experimental data sets. Additional project documentation, including reusable design patterns and a guide for setting up a development environment, was contributed back to the FuGE project. We have shown that an extension of FuGE can be used to transform minimum information requirements in natural language to markup language in XML. Extending FuGE required significant effort, but in our experiences the benefits outweighed the costs. The FuGEFlow is expected to play a central role in describing flow cytometry experiments and ultimately facilitating data exchange including public flow cytometry repositories currently under development.

The path to active living: physical activity through community design in Somerville, Massachusetts.

PubMed

Burke, Noreen M; Chomitz, Virginia R; Rioles, Nicole A; Winslow, Stephen P; Brukilacchio, Lisa B; Baker, Jessie C

2009-12-01

Somerville, Massachusetts, an ethnically diverse, urban community northwest of Boston, presents opportunities and challenges for active living. With a dense street grid, well-maintained sidewalks, neighborhood parks, and existing Community Path, Somerville is very walkable. However, two major surface arteries traverse and bisect neighborhoods, creating pedestrian safety and environmental justice issues. Major goals included promoting increased collaboration and communication among existing active-living efforts; managing the Community Path extension project; encouraging Portuguese-speaking adults to incorporate daily physical activity; leveraging existing urban planning work to establish secure, attractive walking/biking corridors; and embedding active-living messages in everyday life. The Somerville Active Living by Design Partnership (ALbD) successfully created a robust task force that was integrated with citywide active-living efforts, secured resources to increase infrastructure and support for active living, including city-level coordinator positions, and changed decision-making practices that led to incorporation of pedestrian and bicycle transportation priorities into city planning and that influenced the extension of the Community Path. Partnerships must employ sustainability planning early on, utilize skilled facilitative leaders to manage leadership transitions, and engage new partners. Identifying, cultivating, and celebrating champions, especially those with political power, are critical. Working closely with research partners leads to rich data sources for planning and evaluation. Changing the built environment is difficult; working toward smaller wins is realistic and achievable. The synergy of ALbD and other community interventions created a foundation for short-term successes and accelerated political-cultural changes already underway with respect to active living.

Building a biomedical cyberinfrastructure for collaborative research.

PubMed

Schad, Peter A; Mobley, Lee Rivers; Hamilton, Carol M

2011-05-01

For the potential power of genome-wide association studies (GWAS) and translational medicine to be realized, the biomedical research community must adopt standard measures, vocabularies, and systems to establish an extensible biomedical cyberinfrastructure. Incorporating standard measures will greatly facilitate combining and comparing studies via meta-analysis. Incorporating consensus-based and well-established measures into various studies should reduce the variability across studies due to attributes of measurement, making findings across studies more comparable. This article describes two well-established consensus-based approaches to identifying standard measures and systems: PhenX (consensus measures for phenotypes and eXposures), and the Open Geospatial Consortium (OGC). NIH support for these efforts has produced the PhenX Toolkit, an assembled catalog of standard measures for use in GWAS and other large-scale genomic research efforts, and the RTI Spatial Impact Factor Database (SIFD), a comprehensive repository of geo-referenced variables and extensive meta-data that conforms to OGC standards. The need for coordinated development of cyberinfrastructure to support measures and systems that enhance collaboration and data interoperability is clear; this paper includes a discussion of standard protocols for ensuring data compatibility and interoperability. Adopting a cyberinfrastructure that includes standard measures and vocabularies, and open-source systems architecture, such as the two well-established systems discussed here, will enhance the potential of future biomedical and translational research. Establishing and maintaining the cyberinfrastructure will require a fundamental change in the way researchers think about study design, collaboration, and data storage and analysis. Copyright © 2011 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Meditope-Fab interaction: threading the hole.

PubMed

Bzymek, Krzysztof P; Ma, Yuelong; Avery, Kendra N; Horne, David A; Williams, John C

2017-12-01

Meditope, a cyclic 12-residue peptide, binds to a unique binding side between the light and heavy chains of the cetuximab Fab. In an effort to improve the affinity of the interaction, it was sought to extend the side chain of Arg8 in the meditope, a residue that is accessible from the other side of the meditope binding site, in order to increase the number of interactions. These modifications included an n-butyl and n-octyl extension as well as hydroxyl, amine and carboxyl substitutions. The atomic structures of the complexes and the binding kinetics for each modified meditope indicated that each extension threaded through the Fab `hole' and that the carboxyethylarginine substitution makes a favorable interaction with the Fab, increasing the half-life of the complex by threefold compared with the unmodified meditope. Taken together, these studies provide a basis for the design of additional modifications to enhance the overall affinity of this unique interaction.

An evaluation of security measures implemented to address physical threats to water infrastructure in the state of Mississippi.

PubMed

Barrett, Jason R; French, P Edward

2013-01-01

The events of September 11, 2001, increased and intensified domestic preparedness efforts in the United States against terrorism and other threats. The heightened focus on protecting this nation's critical infrastructure included legislation requiring implementation of extensive new security measures to better defend water supply systems against physical, chemical/biological, and cyber attacks. In response, municipal officials have implemented numerous safeguards to reduce the vulnerability of these systems to purposeful intrusions including ongoing vulnerability assessments, extensive personnel training, and highly detailed emergency response and communication plans. This study evaluates fiscal year 2010 annual compliance assessments of public water systems with security measures that were implemented by Mississippi's Department of Health as a response to federal requirements to address these potential terrorist threats to water distribution systems. The results show that 20 percent of the water systems in this state had at least one security violation on their 2010 Capacity Development Assessment, and continued perseverance from local governments is needed to enhance the resiliency and robustness of these systems against physical threats.

Nuclear Engine System Simulation (NESS). Volume 1: Program user's guide

NASA Astrophysics Data System (ADS)

Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman J.

1993-03-01

A Nuclear Thermal Propulsion (NTP) engine system design analysis tool is required to support current and future Space Exploration Initiative (SEI) propulsion and vehicle design studies. Currently available NTP engine design models are those developed during the NERVA program in the 1960's and early 1970's and are highly unique to that design or are modifications of current liquid propulsion system design models. To date, NTP engine-based liquid design models lack integrated design of key NTP engine design features in the areas of reactor, shielding, multi-propellant capability, and multi-redundant pump feed fuel systems. Additionally, since the SEI effort is in the initial development stage, a robust, verified NTP analysis design tool could be of great use to the community. This effort developed an NTP engine system design analysis program (tool), known as the Nuclear Engine System Simulation (NESS) program, to support ongoing and future engine system and stage design study efforts. In this effort, Science Applications International Corporation's (SAIC) NTP version of the Expanded Liquid Engine Simulation (ELES) program was modified extensively to include Westinghouse Electric Corporation's near-term solid-core reactor design model. The ELES program has extensive capability to conduct preliminary system design analysis of liquid rocket systems and vehicles. The program is modular in nature and is versatile in terms of modeling state-of-the-art component and system options as discussed. The Westinghouse reactor design model, which was integrated in the NESS program, is based on the near-term solid-core ENABLER NTP reactor design concept. This program is now capable of accurately modeling (characterizing) a complete near-term solid-core NTP engine system in great detail, for a number of design options, in an efficient manner. The following discussion summarizes the overall analysis methodology, key assumptions, and capabilities associated with the NESS presents an example problem, and compares the results to related NTP engine system designs. Initial installation instructions and program disks are in Volume 2 of the NESS Program User's Guide.

Nuclear Engine System Simulation (NESS). Volume 1: Program user's guide

NASA Technical Reports Server (NTRS)

Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman J.

1993-01-01

A Nuclear Thermal Propulsion (NTP) engine system design analysis tool is required to support current and future Space Exploration Initiative (SEI) propulsion and vehicle design studies. Currently available NTP engine design models are those developed during the NERVA program in the 1960's and early 1970's and are highly unique to that design or are modifications of current liquid propulsion system design models. To date, NTP engine-based liquid design models lack integrated design of key NTP engine design features in the areas of reactor, shielding, multi-propellant capability, and multi-redundant pump feed fuel systems. Additionally, since the SEI effort is in the initial development stage, a robust, verified NTP analysis design tool could be of great use to the community. This effort developed an NTP engine system design analysis program (tool), known as the Nuclear Engine System Simulation (NESS) program, to support ongoing and future engine system and stage design study efforts. In this effort, Science Applications International Corporation's (SAIC) NTP version of the Expanded Liquid Engine Simulation (ELES) program was modified extensively to include Westinghouse Electric Corporation's near-term solid-core reactor design model. The ELES program has extensive capability to conduct preliminary system design analysis of liquid rocket systems and vehicles. The program is modular in nature and is versatile in terms of modeling state-of-the-art component and system options as discussed. The Westinghouse reactor design model, which was integrated in the NESS program, is based on the near-term solid-core ENABLER NTP reactor design concept. This program is now capable of accurately modeling (characterizing) a complete near-term solid-core NTP engine system in great detail, for a number of design options, in an efficient manner. The following discussion summarizes the overall analysis methodology, key assumptions, and capabilities associated with the NESS presents an example problem, and compares the results to related NTP engine system designs. Initial installation instructions and program disks are in Volume 2 of the NESS Program User's Guide.

EVALUATING THE UNIT APPROACH--FARM AND HOME DEVELOPMENT. (TITLE SUPPLIED).

ERIC Educational Resources Information Center

MAYER, RALPH E.; RIECK, ROBERT E.

IN AN EFFORT TO RESOLVE THE DEBATE OF STAFF-TO-FAMILY VS STAFF-TO-MASS RELATIONSHIPS IN FARM EXTENSION WORK, THE 1954 FEDERAL EXTENSION APPROPRIATION BILL AUTHORIZED INCEPTION OF A PERSONAL CONTACT, FAMILY UNIT APPROACH CALLED FARM AND HOME DEVELOPMENT (FHD). THE FHD AGENT WORKED WITH THE FARMER AND HIS WIFE IN AN EDUCATIONAL PROGRAM WHICH…

75 FR 17162 - Dipping and Coating Operations (Dip Tanks) Standard; Extension of the Office of Management and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-05

...] Dipping and Coating Operations (Dip Tanks) Standard; Extension of the Office of Management and Budget's... Standard on Dipping and Coating Operations (Dip Tanks) (29 CFR 1910.126(g)(4)). DATES: Comments must be... of efforts in obtaining information (29 U.S.C. 657). The Standard on Dipping and Coating Operations...

75 FR 21662 - Access to Employee Exposure and Medical Records; Extension of the Office of Management and Budget...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-26

...] Access to Employee Exposure and Medical Records; Extension of the Office of Management and Budget's (OMB... Regulation on Access to Employee Exposure and Medical Records (29 CFR 1910.1020). DATES: Comments must be... operating small businesses, and to reduce to the maximum extent feasible unnecessary duplication of efforts...

What secondary teachers think and do about student engagement in mathematics

NASA Astrophysics Data System (ADS)

Skilling, Karen; Bobis, Janette; Martin, Andrew J.; Anderson, Judy; Way, Jennifer

2016-12-01

What teachers' think about student engagement influences the teaching practices they adopt, their responses to students and the efforts they make in the classroom. Interviews were conducted with 31 mathematics teachers from ten high schools to investigate their perceptions and beliefs about student engagement in mathematics. Teachers also reported the practices they used to engage their students during mathematics lessons. Teacher perceptions of student engagement were categorised according to recognised `types' (behavioural, emotional and cognitive) and `levels' (ranging from disengaged to engaged). The teachers' reports emphasised immediate attention being paid to students' behaviours and overt emotions towards mathematics with fewer and less extensive reports made about students' cognitive engagement. Teachers' abilities to implement practices considered supportive of student engagement were linked to a number of elements, including their self-efficacy. Perceptions of being powerless to engage their students resulted in many teachers limiting their efforts to attempt some form of intervention.

Theoretical research program to study chemical reactions in AOTV bow shock tubes

NASA Technical Reports Server (NTRS)

Taylor, Peter

1992-01-01

Effort continued through this period to refine and expand the SIRIUS/ABACUS program package for CASSCF and RASSCF second derivatives. A new approach to computing the Gaussian integral derivatives that require much of the time in gradient and Hessian calculations was devised. Several different studies were undertaken in the area of application calculations. These include a study of proton transfer in the HF trimer, which provides an analog of rearrangement reactions, and the extension of our previous work on Be and Mg clusters to Ca clusters. In addition, a very accurate investigation of the lowest-lying potential curves of the O2 molecule was completed. These curves are essential for evaluating different models of the terrestrial atmosphere nightglow. The most effort this year was devoted to a large scale investigation of stationary points on the C4H4 surface, and the thermochemistry of acetylene/acetylene reaction.

Fretting Fatigue of Single Crystal/Polycrystalline Nickel Subjected to Blade/Disk Contact Loading

NASA Astrophysics Data System (ADS)

Matlik, J. F.; Murthy, H.; Farris, T. N.

2002-01-01

Fretting fatigue describes the formation and growth of cracks at the edge-of-contact of nominally clamped components subjected to cyclic loading. Components that are known to be subject to fretting fatigue include riveted lap joints and blade/disk contacts in launch vehicle turbomachinery. Recent efforts have shown that conventional mechanics tools, both fatigue and fracture based, can be used to model fretting fatigue experiments leading to successful life predictions. In particular, experiments involving contact load configurations similar to those that occur in the blade/disk connection of gas turbine engines have been performed extensively. Predictions of fretting fatigue life have been compared favorably to experimental observations [1]. Recent efforts are aimed at performing experiments at higher temperatures as shown in the photograph below along with a sample fracture surface. The talk will describe the status of these experiments as will as model developments relevant to the single crystal material properties.

Motorcycle pollution control in Taiwan, Republic of China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, H.W.; Hsiao, H.C.; Walsh, M.P.

1998-12-31

The Taiwan EPA has developed a comprehensive approach to motor vehicle pollution control. Building on its early adoption of US `83 standards for light duty vehicles (starting July 1, 1990) it recently moved to US `87 requirements, which include the 0.2 gram per mile particulate standard, as of July 1, 1995. Heavy duty diesel particulate standards almost as stringent as US `90, 6.0 grams per brake horsepower hour NO{sub x} and 0.7 particulate, using the US transient test procedure, went into effect on July 1, 1993. It is intended that US`94 standards, 5.0 NO{sub x} and 0.25 particulate, will bemore » adopted soon. Clearly the most distinctive feature of the Taiwan program, however, is its motorcycle control effort, reflecting the fact that motorcycles dominate the vehicle fleet and are a substantial source of emissions. This paper will summarize Taiwan`s extensive efforts to address this problem.« less

Studies in Software Cost Model Behavior: Do We Really Understand Cost Model Performance?

NASA Technical Reports Server (NTRS)

Lum, Karen; Hihn, Jairus; Menzies, Tim

2006-01-01

While there exists extensive literature on software cost estimation techniques, industry practice continues to rely upon standard regression-based algorithms. These software effort models are typically calibrated or tuned to local conditions using local data. This paper cautions that current approaches to model calibration often produce sub-optimal models because of the large variance problem inherent in cost data and by including far more effort multipliers than the data supports. Building optimal models requires that a wider range of models be considered while correctly calibrating these models requires rejection rules that prune variables and records and use multiple criteria for evaluating model performance. The main contribution of this paper is to document a standard method that integrates formal model identification, estimation, and validation. It also documents what we call the large variance problem that is a leading cause of cost model brittleness or instability.

Comparison of Aircraft Icing Growth Assessment Software

NASA Technical Reports Server (NTRS)

Wright, William; Potapczuk, Mark G.; Levinson, Laurie H.

2011-01-01

A research project is underway to produce computer software that can accurately predict ice growth under any meteorological conditions for any aircraft surface. An extensive comparison of the results in a quantifiable manner against the database of ice shapes that have been generated in the NASA Glenn Icing Research Tunnel (IRT) has been performed, including additional data taken to extend the database in the Super-cooled Large Drop (SLD) regime. The project shows the differences in ice shape between LEWICE 3.2.2, GlennICE, and experimental data. The project addresses the validation of the software against a recent set of ice-shape data in the SLD regime. This validation effort mirrors a similar effort undertaken for previous validations of LEWICE. Those reports quantified the ice accretion prediction capabilities of the LEWICE software. Several ice geometry features were proposed for comparing ice shapes in a quantitative manner. The resulting analysis showed that LEWICE compared well to the available experimental data.

Anders Celsius' Contributions to Meridian Arc Measurements and the Establishment of an Astronomical Observatory in Uppsala

NASA Astrophysics Data System (ADS)

Stempels, H. C.

Astronomy has been on the curriculum of Uppsala University from at least the middle of the 15th century. However, since Uppsala also was the ecclesiastical centre of Sweden, the acceptance of new ideas, such as the Copernican heliocentric system, was slow. At the same time, more peripheral universities in the Swedish empire, including Dorpat/Tartu, enjoyed a larger freedom. It was not until the early 18th century that a `modern' astronomy emerged in Uppsala. This effort was to a large extent led by Anders Celsius (1701--1744), who was able to establish good international contacts with astronomers in continental Europe. Celsius participated in De Maupertuis' expedition to the far north of Sweden, in order to measure the meridian arc and determine the shape of the Earth. This paper explores how Celsius became involved in De Maupertuis' expedition, and how this effort paved the way to the establishment of a fully equipped astronomical observatory, including an extensive collection of books and instruments, most of which survives up to this day.

An Analysis of the Climate Data Initiative's Data Collection

NASA Astrophysics Data System (ADS)

Ramachandran, R.; Bugbee, K.

2015-12-01

The Climate Data Initiative (CDI) is a broad multi-agency effort of the U.S. government that seeks to leverage the extensive existing federal climate-relevant data to stimulate innovation and private-sector entrepreneurship to support national climate-change preparedness. The CDI project is a systematic effort to manually curate and share openly available climate data from various federal agencies. To date, the CDI has curated seven themes, or topics, relevant to climate change resiliency. These themes include Coastal Flooding, Food Resilience, Water, Ecosystem Vulnerability, Human Health, Energy Infrastructure, and Transportation. Each theme was curated by subject matter experts who selected datasets relevant to the topic at hand. An analysis of the entire Climate Data Initiative data collection and the data curated for each theme offers insights into which datasets are considered most relevant in addressing climate resiliency. Other aspects of the data collection will be examined including which datasets were the most visited or popular and which datasets were the most sought after for curation by the theme teams. Results from the analysis of the CDI collection will be presented in this talk.

De-Arabization of the Bedouin: A Study of an Inevitable Failure

ERIC Educational Resources Information Center

Yonah, Yossi; Abu-Saad, Ismael; Kaplan, Avi

2004-01-01

This paper offers an assessment of the efforts to de-Arabize the Bedouin Arab youth of the Negev. We show that despite the extensive efforts to achieve this goal, they have become pronouncedly alienated from the State of Israel, and are increasingly perceiving themselves as an integral part of Israel's Palestinian Arab national minority. The…

Program Standards and Expectations: Providing Clarity, Consistency, and Focus

ERIC Educational Resources Information Center

Diem, Keith G.

2016-01-01

The effort described in this article resulted from requests for clarity and consistency from new and existing Extension/4-H educators as well as from recommendations by university auditors. The primary purpose of the effort was to clarify standards for effective county-based 4-H youth development programs and to help focus the roles of 4-H…

Assessing the Long-Term Impacts of Water Quality Outreach and Education Efforts on Agricultural Landowners

ERIC Educational Resources Information Center

Jackson-Smith, Douglas B.; McEvoy, Jamie P.

2011-01-01

We assess the long-term effectiveness of outreach and education efforts associated with a water quality improvement project in a watershed located in northern Utah, USA. Conducted 15 years after the original project began, our research examines the lasting impacts of different extension activities on landowners' motivations to participate and…

How to Gather Information on Community Needs and Funding Sources. Resources for Rural Development Series: Handbook No. 1.

ERIC Educational Resources Information Center

Cohen, John M.; Marshall, Terry

One of a series designed to aid community leaders, cooperative extension agents, local government officials, and others in their efforts to gain external resources needed to support local efforts in rural development, this handbook addresses three basic problem areas: gathering information on rural development needs of a community; locating…

Introduction - regional monitoring programs

Treesearch

Richard L. Hutto; C. John Ralph

2005-01-01

There is increasing interest in the initiation of regional or statewide monitoring programs that are less extensive than national efforts such as the Breeding Bird Survey. A number of regional programs have been in existence for a decade or more, so the papers in this section represented an effort to bring together the collective experience of the people who had...

77 FR 6080 - Taking and Importing Marine Mammals; U.S. Navy's Atlantic Fleet Active Sonar Training

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-07

... area occurred from August 2, 2010 to August 1, 2011. Visual Surveys The majority of monitoring effort...) Operating Area (OPAREA), with an extension of survey effort off Cape Hatteras. These locations serve as the... of year-round multi- disciplinary monitoring through the use of shipboard and aerial visual surveys...

GigaTON: an extensive publicly searchable database providing a new reference transcriptome in the pacific oyster Crassostrea gigas.

PubMed

Riviere, Guillaume; Klopp, Christophe; Ibouniyamine, Nabihoudine; Huvet, Arnaud; Boudry, Pierre; Favrel, Pascal

2015-12-02

The Pacific oyster, Crassostrea gigas, is one of the most important aquaculture shellfish resources worldwide. Important efforts have been undertaken towards a better knowledge of its genome and transcriptome, which makes now C. gigas becoming a model organism among lophotrochozoans, the under-described sister clade of ecdysozoans within protostomes. These massive sequencing efforts offer the opportunity to assemble gene expression data and make such resource accessible and exploitable for the scientific community. Therefore, we undertook this assembly into an up-to-date publicly available transcriptome database: the GigaTON (Gigas TranscriptOme pipeliNe) database. We assembled 2204 million sequences obtained from 114 publicly available RNA-seq libraries that were realized using all embryo-larval development stages, adult organs, different environmental stressors including heavy metals, temperature, salinity and exposure to air, which were mostly performed as part of the Crassostrea gigas genome project. This data was analyzed in silico and resulted into 56621 newly assembled contigs that were deposited into a publicly available database, the GigaTON database. This database also provides powerful and user-friendly request tools to browse and retrieve information about annotation, expression level, UTRs, splice and polymorphism, and gene ontology associated to all the contigs into each, and between all libraries. The GigaTON database provides a convenient, potent and versatile interface to browse, retrieve, confront and compare massive transcriptomic information in an extensive range of conditions, tissues and developmental stages in Crassostrea gigas. To our knowledge, the GigaTON database constitutes the most extensive transcriptomic database to date in marine invertebrates, thereby a new reference transcriptome in the oyster, a highly valuable resource to physiologists and evolutionary biologists.

A Proposal for Public and Private Partnership in Extension.

PubMed

Krell, Rayda K; Fisher, Marc L; Steffey, Kevin L

2016-01-01

Public funding for Extension in the United States has been decreasing for many years, but farmers' need for robust information on which to make management decisions has not diminished. The current Extension funding challenges provide motivation to explore a different model for developing and delivering extension. The private sector has partnered with the public sector to fund and conduct agricultural research, but partnering on extension delivery has occurred far less frequently. The fundamental academic strength and established Extension network of the public sector combined with the ability of the private sector to encourage and deliver practical, implementable solutions has the potential to provide measurable benefits to farmers. This paper describes the current Extension climate, presents data from a survey about Extension and industry relationships, presents case studies of successful public- and private-sector extension partnerships, and proposes a framework for evaluating the state of effective partnerships. Synergistic public-private extension efforts could ensure that farmers receive the most current and balanced information available to help with their management decisions.

A Proposal for Public and Private Partnership in Extension

PubMed Central

Krell, Rayda K.; Fisher, Marc L.; Steffey, Kevin L.

2016-01-01

Public funding for Extension in the United States has been decreasing for many years, but farmers’ need for robust information on which to make management decisions has not diminished. The current Extension funding challenges provide motivation to explore a different model for developing and delivering extension. The private sector has partnered with the public sector to fund and conduct agricultural research, but partnering on extension delivery has occurred far less frequently. The fundamental academic strength and established Extension network of the public sector combined with the ability of the private sector to encourage and deliver practical, implementable solutions has the potential to provide measurable benefits to farmers. This paper describes the current Extension climate, presents data from a survey about Extension and industry relationships, presents case studies of successful public- and private-sector extension partnerships, and proposes a framework for evaluating the state of effective partnerships. Synergistic public–private extension efforts could ensure that farmers receive the most current and balanced information available to help with their management decisions. PMID:26949567

Childhood Asthma Disparities in Chicago: Developing Approaches to Health Inequities.

PubMed

Martin, Molly A; Kapheim, Melissa Gutierrez; Erwin, Kim; Ignoffo, Stacy; McMahon, Kate; OʼRourke, Amy; Gerald, Lynn B; Barrett, Meredith; Press, Valerie G; Darabi, Houshang; Krishnan, Jerry A

We conducted a needs assessment to develop an evidence-based, locally tailored asthma care implementation plan for high-risk children with asthma in Chicago. Our team of health policy experts, clinicians, researchers, and designers included extensive stakeholder engagement (N = 162) in a mixed-methods community needs assessment. Results showed the lines of communication and collaboration across sectors were weak; caregivers were the only consistent force and could not always manage this burden. A series of recommendations for interventions and how to implement and measure them were generated. Cooperative, multidisciplinary efforts grounded in the community can target wicked problems such as asthma.

Progress towards extreme attitude testing with Magnetic Suspension and Balance Systems

NASA Technical Reports Server (NTRS)

Britcher, Colin P.; Parker, David H.

1988-01-01

Progress is reported in a research effort aimed towards demonstration of the feasibility of suspension and aerodynamic testing of models at high angles of attack in wind tunnel Magnetic Suspension and Balance Systems. Extensive modifications, described in this paper, have been made to the Southampton University suspension system in order to facilitate this work. They include revision of electromagnet configuration, installation of all-new position sensors and expansion of control system programs. An angle of attack range of 0 to 90 deg is expected for axisymmetric models. To date, suspension up to 80 deg angle of attack has been achieved.

Analysis of Bioprocesses. Dynamic Modeling is a Must.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramkrishna, Doraiswami; Song, Hyun-Seob

2016-01-01

The goal of this paper is to report on the performance of a promising dynamic framework based on the cybernetic concepts which have evolved over three decades. We present case studies of successful dynamic simulations of wild-type strains as well as specific KO mutants on bacteria and yeast. An extensive metabolic engineering effort, including genome scale networks, is called for to secure the methodology and realize its full potential. Towards this end, the software AUMIC is under active further development to enable speedy applications. Its wide use will be enabled by a publication that is shortly due.

VizieR Online Data Catalog: New Kepler planetary candidates (Ofir+, 2013)

NASA Astrophysics Data System (ADS)

Ofir, A.; Dreizler, S.

2013-10-01

We present first results of our efforts to re-analyze the Kepler photometric dataset, searching for planetary transits using an alternative processing pipeline to the one used by the Kepler mission The SARS pipeline was tried and tested extensively by processing all available CoRoT mission data. For this first paper of the series we used this pipeline to search for (additional) planetary transits only in a small subset of stars - the Kepler objects of interest (KOIs), which are already known to include at least one promising planet candidate. (2 data files).

Physical treatment of fever

PubMed Central

Purssell, E.

2000-01-01

Fever is a common symptom of childhood illness, and much time and effort is spent in the pursuit of reducing high temperature. Although antipyretic drugs are the main form of treatment, this report considers the part that physical treatments might play in reducing the temperature of febrile children. Such treatments include tepid sponging, removing clothing, and cooling the environment. Of these treatments, tepid sponging has been studied most extensively, as an addition to paracetamol, but seems to offer little advantage over paracetamol alone. It is likely that other methods might be equally ineffective because they all rely on similar methods of heat loss.

 PMID:10685930

A Pilot Study of the Head Extension Swallowing Exercise: New Method for Strengthening Swallowing-Related Muscle Activity.

PubMed

Oh, Jong-Chi

2016-10-01

This pilot study examined the effect of a new head extension swallowing exercise (HESE) on submental muscle activity and tongue strength in healthy volunteers. Fifteen young adults (10 females and 5 males) were instructed to extend their head backwards as much as possible, and while watching the ceiling, swallowed their saliva every 10 s for a duration of 20 min. Twenty-four treatments were performed over 8 weeks. The outcome variables evaluated at baseline, 4 and 8 weeks of training, and 12-week follow-up included mean and peak submental muscle activation amplitudes during normal and effortful swallowing measured via surface electromyography, and anterior and posterior isometric tongue pressures were measured with the Iowa Oral Performance Instrument. Results indicated that the muscle activation amplitudes during effortful swallowing increased significantly at 4 and 8 weeks compared to baseline (p < 0.025). However, the increases in amplitudes during normal swallowing were minor (nonsignificant) after 8 weeks compared to baseline. The isometric pressures of the tongue tip and the posterior part of the oral tongue were significantly higher at 8 weeks compared to baseline (p < 0.025). Thus, the 8-week HESE protocol significantly improved suprahyoid muscle activity during effortful swallowing as well as the isometric tongue pressures. The HESE appears effective in exercising and strengthening the suprahyoid muscles and tongue muscles in healthy participants. Although encouraging, these results need to be replicated in clinical trials for testing the therapeutic effects of the HESE in older adults and patients with dysphagia who present with decreased hyolaryngeal elevation.

Comparing Emerging XML Based Formats from a Multi-discipline Perspective

NASA Astrophysics Data System (ADS)

Sawyer, D. M.; Reich, L. I.; Nikhinson, S.

2002-12-01

This paper analyzes the similarity and differences among several examples of an emerging generation of Scientific Data Formats that are based on XML technologies. Some of the factors evaluated include the goals of these efforts, the data models, and XML technologies used, and the maturity of currently available software. This paper then investigates the practicality of developing a single set of structural data objects and basic scientific concepts, such as units, that could be used across discipline boundaries and extended by disciplines and missions to create Scientific Data Formats for their communities. This analysis is partly based on an effort sponsored by the ESDIS office at GSFC to compare the Earth Science Markup Language (ESML) and the eXtensible Data Format( XDF), two members of this new generation of XML based Data Description Languages that have been developed by NASA funded efforts in recent years. This paper adds FITSML and potentially CDFML to the list of XML based Scientific Data Formats discussed. This paper draws heavily a Formats Evolution Process Committee (http://ssdoo.gsfc.nasa.gov/nost/fep/) draft white paper primarily developed by Lou Reich, Mike Folk and Don Sawyer to assist the Space Science community in understanding Scientific Data Formats. One of primary conclusions of that paper is that a scientific data format object model should be examined along two basic axes. The first is the complexity of the computer/mathematical data types supported and the second is the level of scientific domain specialization incorporated. This paper also discusses several of the issues that affect the decision on whether to implement a discipline or project specific Scientific Data Format as a formal extension of a general purpose Scientific Data Format or to implement the APIs independently.

The Application of Commercial Advertising Methods to University Extension. Bulletin, 1919, No. 51

ERIC Educational Resources Information Center

Orvis, Mary Burchard

1919-01-01

For many years, colleges, universities, and State departments of education have become more and more conscious of the importance of extension education, and of the obligation resting upon them to promote it in every way practicable. This is especially true of the State university, which, in many States, is now making an honest effort to extend the…

Federal Cooperation in Agricultural Extension Work, Vocational Education, and Vocational Rehabilitation. Bulletin, 1933, No. 15

ERIC Educational Resources Information Center

Blauch, Lloyd E.

1933-01-01

During the past quarter of a century there have been rather continuous and persistent efforts for Federal aid to education. Twenty-one years ago the Congress of the United States enacted the Smith-Lever Agricultural Extension Act, and 3 years later it passed the Smith-Hughes Vocational Education Act. Under the Smith-Lever Act and subsequent…

Measuring the Impact of Termite Prevention Curricula in Hawaii Public Schools in an Area-Wide Extension Program

ERIC Educational Resources Information Center

Mason, Makena; Aihara-Sasaki, Maria; Grace, J. Kenneth

2013-01-01

The efficacy of Educate to Eradicate, a K-12 service-learning science curricula developed as part of a statewide, community-based Extension effort for termite prevention, was evaluated. The curricula use termite biology and control as the basis for science education and have been implemented in over 350 Hawaii public school classrooms with more…

MASTODON: A geosciences simulation tool built using the open-source framework MOOSE

NASA Astrophysics Data System (ADS)

Slaughter, A.

2017-12-01

The Department of Energy (DOE) is currently investing millions of dollars annually into various modeling and simulation tools for all aspects of nuclear energy. An important part of this effort includes developing applications based on the open-source Multiphysics Object Oriented Simulation Environment (MOOSE; mooseframework.org) from Idaho National Laboratory (INL).Thanks to the efforts of the DOE and outside collaborators, MOOSE currently contains a large set of physics modules, including phase field, level set, heat conduction, tensor mechanics, Navier-Stokes, fracture (extended finite-element method), and porous media, among others. The tensor mechanics and contact modules, in particular, are well suited for nonlinear geosciences problems. Multi-hazard Analysis for STOchastic time-DOmaiN phenomena (MASTODON; https://seismic-research.inl.gov/SitePages/Mastodon.aspx)--a MOOSE-based application--is capable of analyzing the response of 3D soil-structure systems to external hazards with current development focused on earthquakes. It is capable of simulating seismic events and can perform extensive "source-to-site" simulations including earthquake fault rupture, nonlinear wave propagation, and nonlinear soil-structure interaction analysis. MASTODON also includes a dynamic probabilistic risk assessment capability that enables analysts to not only perform deterministic analyses, but also easily perform probabilistic or stochastic simulations for the purpose of risk assessment. Although MASTODON has been developed for the nuclear industry, it can be used to assess the risk for any structure subjected to earthquakes.The geosciences community can learn from the nuclear industry and harness the enormous effort underway to build simulation tools that are open, modular, and share a common framework. In particular, MOOSE-based multiphysics solvers are inherently parallel, dimension agnostic, adaptive in time and space, fully coupled, and capable of interacting with other applications. The geosciences community could benefit from existing tools by enabling collaboration between researchers and practitioners throughout the world and advance the state-of-the-art in line with other scientific research efforts.

Efficient Approaches for Propagating Hydrologic Forcing Uncertainty: High-Resolution Applications Over the Western United States

NASA Astrophysics Data System (ADS)

Hobbs, J.; Turmon, M.; David, C. H.; Reager, J. T., II; Famiglietti, J. S.

2017-12-01

NASA's Western States Water Mission (WSWM) combines remote sensing of the terrestrial water cycle with hydrological models to provide high-resolution state estimates for multiple variables. The effort includes both land surface and river routing models that are subject to several sources of uncertainty, including errors in the model forcing and model structural uncertainty. Computational and storage constraints prohibit extensive ensemble simulations, so this work outlines efficient but flexible approaches for estimating and reporting uncertainty. Calibrated by remote sensing and in situ data where available, we illustrate the application of these techniques in producing state estimates with associated uncertainties at kilometer-scale resolution for key variables such as soil moisture, groundwater, and streamflow.

Successful Community-Based Conservation: The Story of Millbank and Pterourus (Papilio) homerus

PubMed Central

Garraway, Eric; Parnell, John; Lewis, Delano S.

2017-01-01

The literature on community-based environmental management is very extensive and the discussion of the pros and cons is continuing. Presented here is an example of a successful interaction between university-based entomologists and a local rural community, detailing the change in the attitude of the town of Millbank, Jamaica, from a Giant Swallowtail Butterfly collecting site to a model for community protection of a species and its environment. A review of some of the research work on community-based conservation efforts is included. These linkages take a considerable time to establish and the efforts spent by scientific personnel, governmental representatives and eco-tourists are itemized to emphasize how specific conservation activities have inspired confidence in the local community, thus engendering trust and mutual respect between the two groups. Reviews of the developed legislative support from both international and state entities also must be in place, and these are included in chronological detail as much as possible. Finally, a review of the long-term funding of educational and other local programs providing a level of stability to the conservation effort, until the local community can take over the protection of the species and/or habitat, is provided. Of utmost importance is a comprehensive educational campaign to not only sensitize the community, but the larger society, so that there can be buy-in from all stakeholders. PMID:28708090

Successful Community-Based Conservation: The Story of Millbank and Pterourus (Papilio) homerus.

PubMed

Garraway, Eric; Parnell, John; Lewis, Delano S

2017-07-14

The literature on community-based environmental management is very extensive and the discussion of the pros and cons is continuing. Presented here is an example of a successful interaction between university-based entomologists and a local rural community, detailing the change in the attitude of the town of Millbank, Jamaica, from a Giant Swallowtail Butterfly collecting site to a model for community protection of a species and its environment. A review of some of the research work on community-based conservation efforts is included. These linkages take a considerable time to establish and the efforts spent by scientific personnel, governmental representatives and eco-tourists are itemized to emphasize how specific conservation activities have inspired confidence in the local community, thus engendering trust and mutual respect between the two groups. Reviews of the developed legislative support from both international and state entities also must be in place, and these are included in chronological detail as much as possible. Finally, a review of the long-term funding of educational and other local programs providing a level of stability to the conservation effort, until the local community can take over the protection of the species and/or habitat, is provided. Of utmost importance is a comprehensive educational campaign to not only sensitize the community, but the larger society, so that there can be buy-in from all stakeholders.

Towards a Global Greenhouse Gas Information System (GHGIS)

NASA Astrophysics Data System (ADS)

Duren, Riley; Butler, James; Rotman, Doug; Miller, Charles; Decola, Phil; Sheffner, Edwin; Tucker, Compton; Mitchiner, John; Jonietz, Karl; Dimotakis, Paul

2010-05-01

Over the next few years, an increasing number of entities ranging from international, national, and regional governments, to businesses and private land-owners, are likely to become more involved in efforts to limit atmospheric concentrations of greenhouse gases. In such a world, geospatially resolved information about the location, amount, and rate of greenhouse gas (GHG) emissions will be needed, as well as the stocks and flows of all forms of carbon through terrestrial ecosystems and in the oceans. The ability to implement policies that limit GHG concentrations would be enhanced by a global, open, and transparent greenhouse gas information system (GHGIS). An operational and scientifically robust GHGIS would combine ground-based and space-based observations, carbon-cycle modeling, GHG inventories, meta-analysis, and an extensive data integration and distribution system, to provide information about sources, sinks, and fluxes of greenhouse gases at policy-relevant temporal and spatial scales. The GHGIS effort was initiated in 2008 as a grassroots inter-agency collaboration intended to rigorously identify the needs for such a system, assess the capabilities of current assets, and suggest priorities for future research and development. We will present a status of the GHGIS effort including our latest analysis and ideas for potential near-term pilot projects with potential relevance to European initiatives including the Global Monitoring for Environment and Security (GMES) and the Integrated Carbon Observing System (ICOS).

A Longitudinal Study of the Social Development of Three-and Four-Year-Old Children in a Preschool Program.

ERIC Educational Resources Information Center

Boger, Robert P.; Cunningham, Jo Lynn

An extensive longitudinal research effort conducted through the Early Childhood Research Center at Michigan State University focused on understanding the forces leading to positive social and emotional development during the preschool years. Because of the rather limited base which was available from other studies for launching such an effort,…

Determinants of field edge habitat restoration on farms in California's Sacramento Valley.

PubMed

Garbach, Kelly; Long, Rachael Freeman

2017-03-15

Degradation and loss of biodiversity and ecosystem services pose major challenges in simplified agricultural landscapes. Consequently, best management practices to create or restore habitat areas on field edges and other marginal areas have received a great deal of recent attention and policy support. Despite this, remarkably little is known about how landholders (farmers and landowners) learn about field edge management practices and which factors facilitate, or hinder, adoption of field edge plantings. We surveyed 109 landholders in California's Sacramento Valley to determine drivers of adoption of field edge plantings. The results show the important influence of landholders' communication networks, which included two key roles: agencies that provide technical support and fellow landholders. The networks of landholders that adopted field edge plantings included both fellow landholders and agencies, whereas networks of non-adopters included either landholders or agencies. This pattern documents that social learning through peer-to-peer information exchange can serve as a complementary and reinforcing pathway with technical learning that is stimulated by traditional outreach and extension programs. Landholder experience with benefits and concerns associated with field edge plantings were also significant predictors of adoption. Our results suggest that technical learning, stimulated by outreach and extension, may provide critical and necessary support for broad-scale adoption of field-edge plantings, but that this alone may not be sufficient. Instead, outreach and extension efforts may need to be strategically expanded to incorporate peer-to-peer communication, which can provide critical information on benefits and concerns. Copyright © 2016 Elsevier Ltd. All rights reserved.

Growing gratitude in undergraduate nursing students: Applying findings from social and psychological domains to nursing education.

PubMed

Fournier, Ann; Sheehan, Caryn

2015-12-01

Millennial students are often characterized as technology focused multitaskers, yet young nursing students are expected to focus on and thoughtfully engage with the person at the center of their caring efforts. Developing gratitude practices requires quiet contemplation and focus. Cultivating an attitude of gratitude in millennial nursing students may be one avenue to address concerns surrounding the provision of relationship based person-centered care by young nurses. In other disciplines, gratitude work has been studied extensively and is associated with several positive outcomes. Assignments included in most nursing programs can easily be modified to include a gratitude focus. Examples of gratitude assignments and the student reflection of these assignments are included here as a call for nurse educators to further study this concept. Copyright © 2015 Elsevier Ltd. All rights reserved.

Multidate, multisensor remote sensing reveals high density of carbon-rich mountain peatlands in the páramo of Ecuador.

PubMed

Hribljan, John A; Suarez, Esteban; Bourgeau-Chavez, Laura; Endres, Sarah; Lilleskov, Erik A; Chimbolema, Segundo; Wayson, Craig; Serocki, Eleanor; Chimner, Rodney A

2017-12-01

Tropical peatlands store a significant portion of the global soil carbon (C) pool. However, tropical mountain peatlands contain extensive peat soils that have yet to be mapped or included in global C estimates. This lack of data hinders our ability to inform policy and apply sustainable management practices to these peatlands that are experiencing unprecedented high rates of land use and land cover change. Rapid large-scale mapping activities are urgently needed to quantify tropical wetland extent and rate of degradation. We tested a combination of multidate, multisensor radar and optical imagery (Landsat TM/PALSAR/RADARSAT-1/TPI image stack) for detecting peatlands in a 2715 km 2 area in the high elevation mountains of the Ecuadorian páramo. The map was combined with an extensive soil coring data set to produce the first estimate of regional peatland soil C storage in the páramo. Our map displayed a high coverage of peatlands (614 km 2 ) containing an estimated 128.2 ± 9.1 Tg of peatland belowground soil C within the mapping area. Scaling-up to the country level, páramo peatlands likely represent less than 1% of the total land area of Ecuador but could contain as much as ~23% of the above- and belowground vegetation C stocks in Ecuadorian forests. These mapping approaches provide an essential methodological improvement applicable to mountain peatlands across the globe, facilitating mapping efforts in support of effective policy and sustainable management, including national and global C accounting and C management efforts. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

The challenge of managing extensively drug-resistant tuberculosis at a referral hospital in the state of São Paulo, Brazil: a report of three cases

PubMed Central

Arbex, Marcos Abdo; de Siqueira, Hélio Ribeiro; D'Ambrosio, Lia; Migliori, Giovanni Battista

2015-01-01

ABSTRACT Here, we report the cases of three patients diagnosed with extensively drug-resistant tuberculosis and admitted to a referral hospital in the state of São Paulo, Brazil, showing the clinical and radiological evolution, as well as laboratory test results, over a one-year period. Treatment was based on the World Health Organization guidelines, with the inclusion of a new proposal for the use of a combination of antituberculosis drugs (imipenem and linezolid). In the cases studied, we show the challenge of creating an acceptable, effective treatment regimen including drugs that are more toxic, are more expensive, and are administered for longer periods. We also show that treatment costs are significantly higher for such patients, which could have an impact on health care systems, even after hospital discharge. We highlight the fact that in extreme cases, such as those reported here, hospitalization at a referral center seems to be the most effective strategy for providing appropriate treatment and increasing the chance of cure. In conclusion, health professionals and governments must make every effort to prevent cases of multidrug-resistant and extensively drug-resistant tuberculosis. PMID:26785966

NASA Extends Chandra Science and Operations Support Contract

NASA Astrophysics Data System (ADS)

2010-01-01

NASA has extended a contract with the Smithsonian Astrophysical Observatory in Cambridge, Mass., to provide science and operational support for the Chandra X-ray Observatory, a powerful tool used to better understand the structure and evolution of the universe. The contract extension with the Smithsonian Astrophysical Observatory provides continued science and operations support to Chandra. This approximately 172 million modification brings the total value of the contract to approximately 545 million for the base effort. The base effort period of performance will continue through Sept. 30, 2013, except for the work associated with the administration of scientific research grants, which will extend through Feb. 28, 2016. The contract type is cost reimbursement with no fee. In addition to the base effort, the contract includes two options for three years each to extend the period of performance for an additional six years. Option 1 is priced at approximately 177 million and Option 2 at approximately 191 million, for a total possible contract value of about $913 million. The contract covers mission operations and data analysis, which includes observatory operations, science data processing and astronomer support. The operations tasks include monitoring the health and status of the observatory and developing and uplinking the observation sequences during Chandra's communication coverage periods. The science data processing tasks include the competitive selection, planning and coordination of science observations and processing and delivery of the resulting scientific data. NASA's Marshall Space Flight Center in Huntsville, Ala, manages the Chandra program for the agency's Science Mission Directorate in Washington. The Smithsonian Astrophysical Observatory controls Chandra's science and flight operations. For more information about the Chandra X-ray Observatory visit: http://chandra.nasa.gov

Note: The full function test explosive generator.

PubMed

Reisman, D B; Javedani, J B; Griffith, L V; Ellsworth, G F; Kuklo, R M; Goerz, D A; White, A D; Tallerico, L J; Gidding, D A; Murphy, M J; Chase, J B

2010-03-01

We have conducted three tests of a new pulsed power device called the full function test. These tests represented the culmination of an effort to establish a high energy pulsed power capability based on high explosive pulsed power (HEPP) technology. This involved an extensive computational modeling, engineering, fabrication, and fielding effort. The experiments were highly successful and a new U.S. record for magnetic energy was obtained.

Contrast and the justification of effort.

PubMed

Klein, Emily D; Bhatt, Ramesh S; Zentall, Thomas R

2005-04-01

When humans are asked to evaluate rewards or outcomes that follow unpleasant (e.g., high-effort) events, they often assign higher value to that reward. This phenomenon has been referred to as cognitive dissonance or justification of effort. There is now evidence that a similar phenomenon can be found in nonhuman animals. When demonstrated in animals, however, it has been attributed to contrast between the unpleasant high effort and the conditioned stimulus for food. In the present experiment, we asked whether an analogous effect could be found in humans under conditions similar to those found in animals. Adult humans were trained to discriminate between shapes that followed a high-effort versus a low-effort response. In test, participants were found to prefer shapes that followed the high-effort response in training. These results suggest the possibility that contrast effects of the sort extensively studied in animals may play a role in cognitive dissonance and other related phenomena in humans.

Bridging the Gap: research informing practice and policy for healthy youth behavior.

PubMed

Chaloupka, Frank J; Johnston, Lloyd D

2007-10-01

Bridging the Gap (BTG) is a collaborative research initiative supported by the Robert Wood Johnson Foundation. Ten years ago, BTG was created to assess the impact of policies, programs, and other environmental influences on adolescent alcohol, tobacco, and illicit drug use and related outcomes. This multidisciplinary, multisite initiative examines these factors at multiple levels of social organization, including schools, communities, and states. More recently, the significant increases in obesity among children, adolescents, and adults led BTG to expand its efforts to include research on the role of policies, programs, and other factors on adolescent obesity and the physical inactivity and dietary habits that contribute to this growing problem. Eleven papers resulting from BTG's obesity-related research are contained in this supplement, along with two papers describing the National Cancer Institute-supported efforts to track relevant state policies. Bridging the Gap involves a variety of data-collection efforts built largely around the Monitoring the Future (MTF) surveys of 8th-, 10th-, and 12th-grade students. These include: surveys of administrators in the MTF schools that gather extensive information on the school food environment, physical education in schools, and other relevant information; collection of contextual information from the communities in which the MTF schools are located; tracking of relevant state policies; and gathering of a wide variety of data from archival and commercial databases. These databases are analyzed individually and in various combinations. Bridging the Gap's extensive research has shown the importance of a range of school, community, state, and other influences in affecting adolescent substance use and related outcomes. BTG's early research on adolescent diet, physical activity, and obesity--much of which is contained in this supplement--similarly demonstrates the role of environmental factors in influencing these outcomes and in explaining observed racial/ethnic and socioeconomic-related disparities in them. The growing recognition of the public health and economic consequences of childhood, adolescent, and adult obesity has led to a variety of policies, programs, and other interventions to stimulate healthy eating and physical activity, often despite the lack of evidence on their impact. BTG and others are working to build the evidence base for effective interventions to address this significant problem, but much remains to be learned.

Implementation of therapeutic hypothermia guidelines for post-cardiac arrest syndrome at a glacial pace: seeking guidance from the knowledge translation literature.

PubMed

Brooks, Steven C; Morrison, Laurie J

2008-06-01

The 2005 International Liaison Committee on Resuscitation (ILCOR) Consensus on Science and Treatment Recommendations document represents the most extensive and rigorous systematic review of the resuscitation literature to date and included evidence-based recommendations for post-resuscitation care. A new recommendation for the induction of mild therapeutic hypothermia for comatose cardiac arrest survivors was included in this document. Accordingly, constituent national member associations of ILCOR, including the American Heart Association, incorporated the recommendation for therapeutic hypothermia into their respective guidelines. Despite these endorsements there is a concern that therapeutic hypothermia is not being used in practice. Data from a number of surveys in Europe and the United States suggest that rates of use among physicians may be as low as 30-40%. Despite the cost and effort associated with the production of these guidelines and the potential impact on patient care, current efforts in implementing the guideline have not achieved widespread success. This commentary explores the issue of underutilization of the American Heart Association guidelines for therapeutic hypothermia and looks to the knowledge translation literature to inform a new approach to implementation. We will review the underlying phenomenon of research implementation into practice, specific barriers to guideline implementation and interventions that may improve therapeutic hypothermia uptake.

Solar dynamic power system development for Space Station Freedom

NASA Technical Reports Server (NTRS)

1993-01-01

The development of a solar dynamic electric power generation system as part of the Space Station Freedom Program is documented. The solar dynamic power system includes a solar concentrator, which collects sunlight; a receiver, which accepts and stores the concentrated solar energy and transfers this energy to a gas; a Brayton turbine, alternator, and compressor unit, which generates electric power; and a radiator, which rejects waste heat. Solar dynamic systems have greater efficiency and lower maintenance costs than photovoltaic systems and are being considered for future growth of Space Station Freedom. Solar dynamic development managed by the NASA Lewis Research Center from 1986 to Feb. 1991 is covered. It summarizes technology and hardware development, describes 'lessons learned', and, through an extensive bibliography, serves as a source list of documents that provide details of the design and analytic results achieved. It was prepared by the staff of the Solar Dynamic Power System Branch at the NASA Lewis Research Center in Cleveland, Ohio. The report includes results from the prime contractor as well as from in-house efforts, university grants, and other contracts. Also included are the writers' opinions on the best way to proceed technically and programmatically with solar dynamic efforts in the future, on the basis of their experiences in this program.

Integrating Six Sigma with total quality management: a case example for measuring medication errors.

PubMed

Revere, Lee; Black, Ken

2003-01-01

Six Sigma is a new management philosophy that seeks a nonexistent error rate. It is ripe for healthcare because many healthcare processes require a near-zero tolerance for mistakes. For most organizations, establishing a Six Sigma program requires significant resources and produces considerable stress. However, in healthcare, management can piggyback Six Sigma onto current total quality management (TQM) efforts so that minimal disruption occurs in the organization. Six Sigma is an extension of the Failure Mode and Effects Analysis that is required by JCAHO; it can easily be integrated into existing quality management efforts. Integrating Six Sigma into the existing TQM program facilitates process improvement through detailed data analysis. A drilled-down approach to root-cause analysis greatly enhances the existing TQM approach. Using the Six Sigma metrics, internal project comparisons facilitate resource allocation while external project comparisons allow for benchmarking. Thus, the application of Six Sigma makes TQM efforts more successful. This article presents a framework for including Six Sigma in an organization's TQM plan while providing a concrete example using medication errors. Using the process defined in this article, healthcare executives can integrate Six Sigma into all of their TQM projects.

SensorWeb 3G: Extending On-Orbit Sensor Capabilities to Enable Near Realtime User Configurability

NASA Technical Reports Server (NTRS)

Mandl, Daniel; Cappelaere, Pat; Frye, Stuart; Sohlberg, Rob; Ly, Vuong; Chien, Steve; Tran, Daniel; Davies, Ashley; Sullivan, Don; Ames, Troy;

Cross-border outbreak of extensively drug-resistant tuberculosis linked to a university in Romania.

PubMed

Popovici, O; Monk, Ph; Chemtob, D; Chiotan, D; Freidlin, P J; Groenheit, R; Haanperä, M; Homorodean, D; Mansjö, M; Robinson, E; Rorman, E; Smith, G; Soini, H; Van Der Werf, M J

2018-05-01

Extensively drug-resistant (XDR) tuberculosis (TB) poses a threat to public health due to its complicated, expensive and often unsuccessful treatment. A cluster of three XDR TB cases was detected among foreign medical students of a Romanian university. The contact investigations included tuberculin skin testing or interferon gamma release assay, chest X-ray, sputum smear microscopy, culture, drug susceptibility testing, genotyping and whole-genome sequencing (WGS), and were addressed to students, personnel of the university, family members or other close contacts of the cases. These investigations increased the total number of cases to seven. All confirmed cases shared a very similar WGS profile. Two more cases were epidemiologically linked, but no laboratory confirmation exists. Despite all the efforts done, the source of the outbreak was not identified, but the transmission was controlled. The investigation was conducted by a team including epidemiologists and microbiologists from five countries (Finland, Israel, Romania, Sweden and the UK) and from the European Centre for Disease Prevention and Control. Our report shows how countries can collaborate to control the spread of XDR TB by exchanging information about cases and their contacts to enable identification of additional cases and transmission and to perform the source investigation.

On-line upgrade of program modules using AdaPT

NASA Technical Reports Server (NTRS)

Waldrop, Raymond S.; Volz, Richard A.; Smith, Gary W.; Goldsack, Stephen J.; Holzbach-Valero, A. A.

1993-01-01

One purpose of our research is the investigation of the effectiveness and expressiveness of AdaPT, a set of language extensions to Ada 83, for distributed systems. As a part of that effort, we are now investigating the subject of replacing, e.g. upgrading, software modules while the software system remains in operation. The AdaPT language extensions provide a good basis for this investigation for several reasons: they include the concept of specific, self-contained program modules which can be manipulated; support for program configuration is included in the language; and although the discussion will be in terms of the AdaPT language, the AdaPT to Ada 83 conversion methodology being developed as another part of this project will provide a basis for the application of our findings to Ada 83 and Ada 9X systems. The purpose of this investigation is to explore the basic mechanisms of the replacement process. With this purpose in mind, we will avoid including issues whose presence would obscure these basic mechanisms by introducing additional, unrelated concerns. Thus, while replacement in the presence of real-time deadlines, heterogeneous systems, and unreliable networks is certainly a topic of interest, we will first gain an understanding of the basic processes in the absence of such concerns. The extension of the replacement process to more complex situations can be made later. A previous report established an overview of the module replacement problem, a taxonomy of the various aspects of the replacement process, and a solution to one case in the replacement taxonomy. This report provides solutions to additional cases in the replacement process taxonomy: replacement of partitions with state and replacement of nodes. The solutions presented here establish the basic principles for module replacement. Extension of these solutions to other more complicated cases in the replacement taxonomy is direct, though requiring substantial work beyond the available funding.

Broadband Scattering from Sand and Sand/Mud Sediments with Extensive Environmental Characterization

DTIC Science & Technology

2017-01-30

experiment , extensive envi- ronmental characterization was also performed to support data/model comparisons for both experimental efforts. The site...mechanisms, potentially addressing questions left unresolved from the previous sediment acoustics experiments , SAX99 and SAX04. This work was also to provide...environmental characterization to support the analysis of data collected during the Target and Reverberation Experiment in 2013 (TREX13) as well as

The JPEG XT suite of standards: status and future plans

NASA Astrophysics Data System (ADS)

Richter, Thomas; Bruylants, Tim; Schelkens, Peter; Ebrahimi, Touradj

2015-09-01

The JPEG standard has known an enormous market adoption. Daily, billions of pictures are created, stored and exchanged in this format. The JPEG committee acknowledges this success and spends continued efforts in maintaining and expanding the standard specifications. JPEG XT is a standardization effort targeting the extension of the JPEG features by enabling support for high dynamic range imaging, lossless and near-lossless coding, and alpha channel coding, while also guaranteeing backward and forward compatibility with the JPEG legacy format. This paper gives an overview of the current status of the JPEG XT standards suite. It discusses the JPEG legacy specification, and details how higher dynamic range support is facilitated both for integer and floating-point color representations. The paper shows how JPEG XT's support for lossless and near-lossless coding of low and high dynamic range images is achieved in combination with backward compatibility to JPEG legacy. In addition, the extensible boxed-based JPEG XT file format on which all following and future extensions of JPEG will be based is introduced. This paper also details how the lossy and lossless representations of alpha channels are supported to allow coding transparency information and arbitrarily shaped images. Finally, we conclude by giving prospects on upcoming JPEG standardization initiative JPEG Privacy & Security, and a number of other possible extensions in JPEG XT.

FuGEFlow: data model and markup language for flow cytometry

PubMed Central

Qian, Yu; Tchuvatkina, Olga; Spidlen, Josef; Wilkinson, Peter; Gasparetto, Maura; Jones, Andrew R; Manion, Frank J; Scheuermann, Richard H; Sekaly, Rafick-Pierre; Brinkman, Ryan R

2009-01-01

Background Flow cytometry technology is widely used in both health care and research. The rapid expansion of flow cytometry applications has outpaced the development of data storage and analysis tools. Collaborative efforts being taken to eliminate this gap include building common vocabularies and ontologies, designing generic data models, and defining data exchange formats. The Minimum Information about a Flow Cytometry Experiment (MIFlowCyt) standard was recently adopted by the International Society for Advancement of Cytometry. This standard guides researchers on the information that should be included in peer reviewed publications, but it is insufficient for data exchange and integration between computational systems. The Functional Genomics Experiment (FuGE) formalizes common aspects of comprehensive and high throughput experiments across different biological technologies. We have extended FuGE object model to accommodate flow cytometry data and metadata. Methods We used the MagicDraw modelling tool to design a UML model (Flow-OM) according to the FuGE extension guidelines and the AndroMDA toolkit to transform the model to a markup language (Flow-ML). We mapped each MIFlowCyt term to either an existing FuGE class or to a new FuGEFlow class. The development environment was validated by comparing the official FuGE XSD to the schema we generated from the FuGE object model using our configuration. After the Flow-OM model was completed, the final version of the Flow-ML was generated and validated against an example MIFlowCyt compliant experiment description. Results The extension of FuGE for flow cytometry has resulted in a generic FuGE-compliant data model (FuGEFlow), which accommodates and links together all information required by MIFlowCyt. The FuGEFlow model can be used to build software and databases using FuGE software toolkits to facilitate automated exchange and manipulation of potentially large flow cytometry experimental data sets. Additional project documentation, including reusable design patterns and a guide for setting up a development environment, was contributed back to the FuGE project. Conclusion We have shown that an extension of FuGE can be used to transform minimum information requirements in natural language to markup language in XML. Extending FuGE required significant effort, but in our experiences the benefits outweighed the costs. The FuGEFlow is expected to play a central role in describing flow cytometry experiments and ultimately facilitating data exchange including public flow cytometry repositories currently under development. PMID:19531228

Evaluating Agronomic Performance and Investigating Molecular Structure of Drought and Heat Tolerant Wild Alfalfa (Medicago sativa L.) Collection from the Southeastern Turkey.

PubMed

Basbag, Mehmet; Aydin, Ali; Sakiroglu, Muhammet

2017-02-01

Drought is a major stress factor for agricultural production including alfalfa production. One way to counterbalance the yield losses is the introgression of drought tolerant germplasm into breeding programs. As an effort to exploit such germplasm, 16 individual plants were selected from the Southeastern Turkey from their natural habitat and clonally propagated in field trials with an ultimate goal to use the germplasm as parents for releasing a synthetic cultivar. Forage yield and forage quality traits were evaluated and molecular genetic diversity among genotypes were determined using inter simple sequence repeat markers. Genotypes showed a variation from growth habit to yield and quality traits indicating sufficient phenotypic variation for diverse breeding efforts (for grazing or harvesting) and long term selection schemes. A large amount of genetic variation was observed even with a limited number of marker and genotypes. However, no pattern of spatial genetic structure was observed for the scale of the study when genetic variation is linked to the geographic origin. We conclude that ex situ natural variation provides a wealth of germplasm that could be incorporated into breeding programs aiming to improve drought tolerance. We also suggest an extensive collection of seeds/plant tissue from unique plants with desirable traits rather than putting more efforts to create a spatial germplasm sampling efforts in narrow regions.

Protecting the Local Dark-Sky Areas around the International Observatories in Chile.

NASA Astrophysics Data System (ADS)

Smith, M. G.

2001-12-01

This report covers efforts by IAU Commission 50's new Working Group on Light Pollution to slow or halt the spread of incipient light pollution near the VLT, the Magellan 6.5m telescopes, Gemini South, SOAR, Blanco and many smaller telescopes in Chile. An effort has just begun to protect the ALMA site in Northern Chile from RFI. Such work includes extensive outreach programs to the local population, schools and industry as well as to local, regional and national levels of government in Chile. The group is working internationally with such organizations as the IDA; one member has recently led the production of "The first world atlas of the artificial night-sky brightness". These efforts have resulted in the first national-level environmental legislation covering dark skies as part of a government effort to protect the environment. Chilean manufacturers are now producing competitive, full-cut-off, street lighting designed specifically to comply with the new legislation. The Chilean national tourism agency is supporting "Astronomical Tourism" based on the dark, clear skies of Chile. An international conference on Controlling Light Pollution and RFI will be held in La Serena, Chile on 5-7 March, 2002, backed up by a parallel meeting of Chilean amateur astronomers. Much work remains to be done. Most of this work is supported by funding from the US National Science Foundation through CTIO, and from ESO, OCIW and CONAMA.

Helioviewer.org: Browsing Very Large Image Archives Online Using JPEG 2000

NASA Astrophysics Data System (ADS)

Hughitt, V. K.; Ireland, J.; Mueller, D.; Dimitoglou, G.; Garcia Ortiz, J.; Schmidt, L.; Wamsler, B.; Beck, J.; Alexanderian, A.; Fleck, B.

2009-12-01

As the amount of solar data available to scientists continues to increase at faster and faster rates, it is important that there exist simple tools for navigating this data quickly with a minimal amount of effort. By combining heterogeneous solar physics datatypes such as full-disk images and coronagraphs, along with feature and event information, Helioviewer offers a simple and intuitive way to browse multiple datasets simultaneously. Images are stored in a repository using the JPEG 2000 format and tiled dynamically upon a client's request. By tiling images and serving only the portions of the image requested, it is possible for the client to work with very large images without having to fetch all of the data at once. In addition to a focus on intercommunication with other virtual observatories and browsers (VSO, HEK, etc), Helioviewer will offer a number of externally-available application programming interfaces (APIs) to enable easy third party use, adoption and extension. Recent efforts have resulted in increased performance, dynamic movie generation, and improved support for mobile web browsers. Future functionality will include: support for additional data-sources including RHESSI, SDO, STEREO, and TRACE, a navigable timeline of recorded solar events, social annotation, and basic client-side image processing.

Quantum image processing: A review of advances in its security technologies

NASA Astrophysics Data System (ADS)

Yan, Fei; Iliyasu, Abdullah M.; Le, Phuc Q.

In this review, we present an overview of the advances made in quantum image processing (QIP) comprising of the image representations, the operations realizable on them, and the likely protocols and algorithms for their applications. In particular, we focus on recent progresses on QIP-based security technologies including quantum watermarking, quantum image encryption, and quantum image steganography. This review is aimed at providing readers with a succinct, yet adequate compendium of the progresses made in the QIP sub-area. Hopefully, this effort will stimulate further interest aimed at the pursuit of more advanced algorithms and experimental validations for available technologies and extensions to other domains.

Mechanism Design Principle for Optical-Precision, Deployable Instruments

NASA Technical Reports Server (NTRS)

Lake, Mark S.; Hachkowski, M. Roman

2000-01-01

The present paper is intended to be a guide for the design of 'microdynamically quiet' deployment mechanisms for optical-precision structures, such as deployable telescope mirrors and optical benches. Many of the guidelines included herein come directly from the field of optomechanical engineering, and are neither newly developed guidelines nor are they uniquely applicable to high-precision deployment mechanisms. However, the application of these guidelines to the design of deployment mechanisms is a rather new practice, so efforts are made herein to illustrate the process through the discussion of specific examples. The present paper summarizes a more extensive set of design guidelines for optical-precision mechanisms that are under development.

Step up to the bar: avoiding discrimination in professional licensure.

PubMed

Appelbaum, Paul S

2015-04-01

In their efforts to protect the public from impaired professionals, licensure boards often have created special rules for applicants with mental disorders. The authorities in charge of admission to the Louisiana bar required extensive disclosure of mental health status, even if an applicant's professional functioning was not impaired. After the U.S. Department of Justice found that Louisiana's practices violated applicants' rights under the Americans with Disabilities Act, the state agreed to focus on applicants' functional impairment rather than on mental disorders. This settlement may provide a model for licensure boards in other states and for other professions, including the health professions.

Development of Stiff and Extendible Electromagnetic Sensors for Space Missions

NASA Astrophysics Data System (ADS)

Kasaba, Y.; Kumamoto, A.; Ishisaka, K.; Kojima, H.; Higuchi, K.; Watanabe, A.; Watanabe, K.

2010-05-01

We developed three types of stiff and extendible electromagnetic sensors in rigid monopole antenna, loop antenna, and Yagi-Uda antenna for future space missions. They are based on carbon fiber reinforced plastic (CFRP) technologies, in order to fulfill severe requirements, i.e. enough stiffness, light mass, compact storage, safe extension, and reasonable test efforts. One of them, rigid monopole antennas, coupled with an inflatable actuator system, was successfully used in the JAXA S-520-23 sounding rocket experiment in September 2007. Applications of those antennas are expected in space plasma missions including the SCOPE program, sounding rocket experiments, planetary radar remote sensing, and landing radio measurements.

Modeling strength data for CREW CHIEF

NASA Technical Reports Server (NTRS)

Mcdaniel, Joe W.

1990-01-01

The Air Force has developed CREW CHIEF, a computer-aided design (CAD) tool for simulating and evaluating aircraft maintenance to determine if the required activities are feasible. CREW CHIEF gives the designer the ability to simulate maintenance activities with respect to reach, accessibility, strength, hand tool operation, and materials handling. While developing the CREW CHIEF, extensive research was performed to describe workers strength capabilities for using hand tools and manual handling of objects. More than 100,000 strength measures were collected and modeled for CREW CHIEF. These measures involved both male and female subjects in the 12 maintenance postures included in CREW CHIEF. The data collection and modeling effort are described.

The inclusion of an online journal in PubMed central - a difficult path.

PubMed

Grech, Victor

2016-01-01

The indexing of a journal in a prominent database (such as PubMed) is an important imprimatur. Journals accepted for inclusion in PubMed Central (PMC) are automatically indexed in PubMed but must provide the entire contents of their publications as XML-tagged (Extensible Markup Language) data files compliant with PubMed's document type definition (DTD). This paper describes the various attempts that the journal Images in Paediatric Cardiology made in its efforts to convert the journal contents (including all of the extant backlog) to PMC-compliant XML for archiving and indexing in PubMed after the journal was accepted for inclusion by the database.

Sociocultural Behavior Influence Modelling & Assessment: Current Work and Research Frontiers.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernard, Michael Lewis

A common problem associated with the effort to better assess potential behaviors of various individuals within different countries is the shear difficulty in comprehending the dynamic nature of populations, particularly over time and considering feedback effects. This paper discusses a theory-based analytical capability designed to enable analysts to better assess the influence of events on individuals interacting within a country or region. These events can include changes in policy, man-made or natural disasters, migration, war, or other changes in environmental/economic conditions. In addition, this paper describes potential extensions of this type of research to enable more timely and accurate assessments.

Final Determinations Regarding the Applicability of the Clean Air Act's NSPS and PSD Requirements to the Proposed Life Extension Project at the Port Washington Steam Electric Generating Station Owned by WEPCO

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Fuels and Lubrication Researcher at the Aircraft Engine Research Laboratory

NASA Image and Video Library

1943-08-21

A researcher at the National Advisory Committee for Aeronautics (NACA) Aircraft Engine Research Laboratory studies the fuel ignition process. Improved fuels and lubrication was an area of particular emphasis at the laboratory during World War II. The military sought to use existing types of piston engines in order to get large numbers of aircraft into the air as quickly as possible. To accomplish its goals, however, the military needed to increase the performance of these engines without having to wait for new models or extensive redesigns. The Aircraft Engine Research Laboratory was called on to lead this effort. The use of superchargers successfully enhanced engine performance, but the resulting heat increased engine knock [fuel detonation] and structural wear. These effects could be offset with improved cooling, lubrication, and fuel mixtures. The NACA researchers in the Fuels and Lubrication Division concentrated on new synthetic fuels, higher octane fuels, and fuel-injection systems. The laboratory studied 16 different types of fuel blends during the war, including extensive investigations of triptane and xylidine.

Interpreted Cooper-Harper for broader use

NASA Technical Reports Server (NTRS)

Green, David L.; Andrews, Hal; Gallagher, Donald W.

1993-01-01

The current aircraft assessment process typically makes extensive use of operational personnel during simulations and operational evaluations, with increased emphasis on evaluating the many pilot and/or operator/aircraft control loops. The need for a crew assessment in this broader arena has produced a variety of rating scales. The Cooper-Harper Rating Scale is frequently misused and routinely overlooked in the process, for these applications often extend the scale's use beyond its originally intended application. This paper agrees with the broader application of the Cooper-Harper Rating Scale and presents a concept for the development of a 'use unique' Interpreted Cooper-Harper Scale to help achieve this objective. This interpreted scale concept was conceived during efforts to support an FAA evaluation of a night vision enhancement system. It includes descriptive extensions, which are faithful to the intent of the current Cooper-Harper Scale and should provide the kind of detail that has historically been provided by trained test pilots in their explanatory comments.

Synthetic fuels for ground transportation with special emphasis on hydrogen

NASA Technical Reports Server (NTRS)

Singh, J. J.

1975-01-01

The role of various synthetic fuels, for ground transportation in the United States, was examined for the near term (by 1985) and the longer term applications (1985-2000 and beyond 2000). Feasible options include synthetic oil, methanol, electric propulsion, and hydrogen. It is concluded that (1) the competition during the next 50 years will be for the fuels of all types, rather than among the fuels; (2) extensive domestic oil and gas exploration should be initiated concurrent with the development of several alternate fuels and related ancillaries; and (3) hydrogen, as an automotive fuel, seems to be equivalent to gasoline for optimum fuel to air mixtures. As a pollution free, high energy density fuel, hydrogen deserves consideration as the logical replacement for the hydrocarbons. Several research and development requirements, essential for the implementation of hydrogen economy for ground transportation, were identified. Extensive engineering development and testing activities should be initiated to establish hydrogen as the future automotive fuel, followed by demonstration projects and concerted efforts at public education.

Performance of Partially Fluorinated Polyimide Insulation for Aerospace Applications

NASA Technical Reports Server (NTRS)

Hammoud, Ahmad N.; Stavnes, Mark W.; Ide, James R.; Muegge, ED

1995-01-01

Polyimide has been used extensively as the primary wiring insulation in commercial planes, military aircraft, and space vehicles due to its low weight, high service temperature, and good dielectric strength. New failure modes, however, have been associated with the use of polyimide because of the susceptibility of the insulation to pyrolization and arc tracking. A new wiring construction utilizing partially fluorinated polyimide insulation has been tested and compared with the standard military polyimide wire. Electrical properties which were investigated include AC corona inception and extinction voltages (sea level and 60,000 feet), time/current to smoke, and wire fusing time. The two constructions were also characterized in terms of their mechanical properties including abrasion resistance, dynamic cut through, and notch propagation. These test efforts and the results obtained are presented and discussed.

Performance of partially fluorinated polyimide insulation for aerospace applications

NASA Astrophysics Data System (ADS)

Hammoud, Ahmad N.; Stavnes, Mark W.; Ide, James R.; Muegge, Ed

1995-08-01

Polyimide has been used extensively as the primary wiring insulation in commercial planes, military aircraft, and space vehicles due to its low weight, high service temperature, and good dielectric strength. New failure modes, however, have been associated with the use of polyimide because of the susceptibility of the insulation to pyrolization and arc tracking. A new wiring construction utilizing partially fluorinated polyimide insulation has been tested and compared with the standard military polyimide wire. Electrical properties which were investigated include AC corona inception and extinction voltages (sea level and 60,000 feet), time/current to smoke, and wire fusing time. The two constructions were also characterized in terms of their mechanical properties including abrasion resistance, dynamic cut through, and notch propagation. These test efforts and the results obtained are presented and discussed.

Maintaining ecosystem function and services in logged tropical forests.

PubMed

Edwards, David P; Tobias, Joseph A; Sheil, Douglas; Meijaard, Erik; Laurance, William F

2014-09-01

Vast expanses of tropical forests worldwide are being impacted by selective logging. We evaluate the environmental impacts of such logging and conclude that natural timber-production forests typically retain most of their biodiversity and associated ecosystem functions, as well as their carbon, climatic, and soil-hydrological ecosystem services. Unfortunately, the value of production forests is often overlooked, leaving them vulnerable to further degradation including post-logging clearing, fires, and hunting. Because logged tropical forests are extensive, functionally diverse, and provide many ecosystem services, efforts to expand their role in conservation strategies are urgently needed. Key priorities include improving harvest practices to reduce negative impacts on ecosystem functions and services, and preventing the rapid conversion and loss of logged forests. Copyright © 2014 Elsevier Ltd. All rights reserved.

Taking Innovation To Scale In Primary Care Practices: The Functions Of Health Care Extension.

PubMed

Ono, Sarah S; Crabtree, Benjamin F; Hemler, Jennifer R; Balasubramanian, Bijal A; Edwards, Samuel T; Green, Larry A; Kaufman, Arthur; Solberg, Leif I; Miller, William L; Woodson, Tanisha Tate; Sweeney, Shannon M; Cohen, Deborah J

2018-02-01

Health care extension is an approach to providing external support to primary care practices with the aim of diffusing innovation. EvidenceNOW was launched to rapidly disseminate and implement evidence-based guidelines for cardiovascular preventive care in the primary care setting. Seven regional grantee cooperatives provided the foundational elements of health care extension-technological and quality improvement support, practice capacity building, and linking with community resources-to more than two hundred primary care practices in each region. This article describes how the cooperatives varied in their approaches to extension and provides early empirical evidence that health care extension is a feasible and potentially useful approach for providing quality improvement support to primary care practices. With investment, health care extension may be an effective platform for federal and state quality improvement efforts to create economies of scale and provide practices with more robust and coordinated support services.

Experimental Characterization and Micromechanical Modeling of Woven Carbon/Copper Composites

NASA Technical Reports Server (NTRS)

Bednarcyk, Brett A.; Pauly, Christopher C.; Pindera, Marek-Jerzy

1997-01-01

The results of an extensive experimental characterization and a preliminary analytical modeling effort for the elastoplastic mechanical behavior of 8-harness satin weave carbon/copper (C/Cu) composites are presented. Previous experimental and modeling investigations of woven composites are discussed, as is the evolution of, and motivation for, the continuing research on C/Cu composites. Experimental results of monotonic and cyclic tension, compression, and Iosipescu shear tests, and combined tension-compression tests, are presented. With regard to the test results, emphasis is placed on the effect of strain gauge size and placement, the effect of alloying the copper matrix to improve fiber-matrix bonding, yield surface characterization, and failure mechanisms. The analytical methodology used in this investigation consists of an extension of the three-dimensional generalized method of cells (GMC-3D) micromechanics model, developed by Aboudi (1994), to include inhomogeneity and plasticity effects on the subcell level. The extension of the model allows prediction of the elastoplastic mechanical response of woven composites, as represented by a true repeating unit cell for the woven composite. The model is used to examine the effects of refining the representative geometry of the composite, altering the composite overall fiber volume fraction, changing the size and placement of the strain gauge with respect to the composite's reinforcement weave, and including porosity within the infiltrated fiber yarns on the in-plane elastoplastic tensile, compressive, and shear response of 8-harness satin C/Cu. The model predictions are also compared with the appropriate monotonic experimental results.

Lewis Research Center earth resources program

NASA Technical Reports Server (NTRS)

Mark, H.

1972-01-01

The Lewis Research Center earth resources program efforts are in the areas of: (1) monitoring and rapid evaluation of water quality; (2) determining ice-type and ice coverage distribution to aid operations in a possible extension of the Great Lakes ice navigation and shipping season; (3) monitoring spread of crop viruses; and (4) extent of damage to strip mined areas as well as success of efforts to rehabilitate such areas for agriculture.

Toward a Mechanistic Source Term in Advanced Reactors: Characterization of Radionuclide Transport and Retention in a Sodium Cooled Fast Reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunett, Acacia J.; Bucknor, Matthew; Grabaskas, David

A vital component of the U.S. reactor licensing process is an integrated safety analysis in which a source term representing the release of radionuclides during normal operation and accident sequences is analyzed. Historically, source term analyses have utilized bounding, deterministic assumptions regarding radionuclide release. However, advancements in technical capabilities and the knowledge state have enabled the development of more realistic and best-estimate retention and release models such that a mechanistic source term assessment can be expected to be a required component of future licensing of advanced reactors. Recently, as part of a Regulatory Technology Development Plan effort for sodium cooledmore » fast reactors (SFRs), Argonne National Laboratory has investigated the current state of knowledge of potential source terms in an SFR via an extensive review of previous domestic experiments, accidents, and operation. As part of this work, the significant sources and transport processes of radionuclides in an SFR have been identified and characterized. This effort examines all stages of release and source term evolution, beginning with release from the fuel pin and ending with retention in containment. Radionuclide sources considered in this effort include releases originating both in-vessel (e.g. in-core fuel, primary sodium, cover gas cleanup system, etc.) and ex-vessel (e.g. spent fuel storage, handling, and movement). Releases resulting from a primary sodium fire are also considered as a potential source. For each release group, dominant transport phenomena are identified and qualitatively discussed. The key product of this effort was the development of concise, inclusive diagrams that illustrate the release and retention mechanisms at a high level, where unique schematics have been developed for in-vessel, ex-vessel and sodium fire releases. This review effort has also found that despite the substantial range of phenomena affecting radionuclide release, the current state of knowledge is extensive, and in most areas may be sufficient. Several knowledge gaps were identified, such as uncertainty in release from molten fuel and availability of thermodynamic data for lanthanides and actinides in liquid sodium. However, the overall findings suggest that high retention rates can be expected within the fuel and primary sodium for all radionuclides other than noble gases.« less

Indian programme on middle atmosphere - Some results

NASA Astrophysics Data System (ADS)

Mitra, A. P.

An account of the very extensive program on the middle atmosphere carried out in India since 1982 is presented. Three rocket ranges (Thumba, SHAR and Balasore), a high altitude balloon facility at Hyderabad, a lidar at Thumba, a laser heterodyning system at Delhi, a meteor radar in Thumba, a network of UVB and multiwavelength radiometers, and a host of conventional ground based facilities scattered over the entire subcontinent were used. These facilities covered a range of latitudes from 8 deg N to 34 deg N and largely around the same longitude zone of 75 deg E. The nature of the Indian effort is the emphasis on campaign mode operations, knitting special rocket and balloon efforts with more conventional ground based activities around specific themes. Major campaigns carried out included: (1) Indo-Soviet Ozone Intercomparison campaigns in 1983 and 1987, (2) Aerosol campaign (3), Ionization and conductivity campaigns, (4) Equatorial Wave Campaign, (5) Antarctic Ozone Hole campaign in Dakshin Gangotri. A few of the more important findings are outlined.

HIV-1 vaccine strategies utilizing viral vectors including antigen- displayed inoviral vectors.

PubMed

Hassapis, Kyriakos A; Kostrikis, Leondios G

2013-12-01

Antigen-presenting viral vectors have been extensively used as vehicles for the presentation of antigens to the immune system in numerous vaccine strategies. Particularly in HIV vaccine development efforts, two main viral vectors have been used as antigen carriers: (a) live attenuated vectors and (b) virus-like particles (VLPs); the former, although highly effective in animal studies, cannot be clinically tested in humans due to safety concerns and the latter have failed to induce broadly neutralizing anti-HIV antibodies. For more than two decades, Inoviruses (non-lytic bacterial phages) have also been utilized as antigen carriers in several vaccine studies. Inoviral vectors are important antigen-carriers in vaccine development due to their ability to present an antigen on their outer architecture in many copies and to their natural high immunogenicity. Numerous fundamental studies have been conducted, which have established the unique properties of antigen-displayed inoviral vectors in HIV vaccine efforts. The recent isolation of new, potent anti-HIV broadly neutralizing monoclonal antibodies provides a new momentum in this emerging technology.

Comparative Approaches to Understanding the Relation Between Aging and Physical Function

PubMed Central

Cesari, Matteo; Seals, Douglas R.; Shively, Carol A.; Carter, Christy S.

2016-01-01

Despite dedicated efforts to identify interventions to delay aging, most promising interventions yielding dramatic life-span extension in animal models of aging are often ineffective when translated to clinical trials. This may be due to differences in primary outcomes between species and difficulties in determining the optimal clinical trial paradigms for translation. Measures of physical function, including brief standardized testing batteries, are currently being proposed as biomarkers of aging in humans, are predictive of adverse health events, disability, and mortality, and are commonly used as functional outcomes for clinical trials. Motor outcomes are now being incorporated into preclinical testing, a positive step toward enhancing our ability to translate aging interventions to clinical trials. To further these efforts, we begin a discussion of physical function and disability assessment across species, with special emphasis on mice, rats, monkeys, and man. By understanding how physical function is assessed in humans, we can tailor measurements in animals to better model those outcomes to establish effective, standardized translational functional assessments with aging. PMID:25910845

Data visualization, time-series analysis, and mass-balance modeling of hydrologic and water-quality data for the McTier Creek watershed, South Carolina, 2007-2009

USGS Publications Warehouse

Benedict, Stephen T.; Conrads, Paul; Feaster, Toby D.; Journey, Celeste A.; Golden, Heather E.; Knightes, Christopher D.; Davis, Gary M.; Bradley, Paul M.

2012-01-01

The McTier Creek watershed is located in the headwaters of the Edisto River Basin, which is in the Coastal Plain region of South Carolina. The Edisto ecosystem has some of the highest recorded fish-tissue mercury concentrations in the United States. In an effort to advance the understanding of the fate and transport of mercury in stream ecosystems, the U.S. Geological Survey, as part of its National Water-Quality Assessment Program, initiated a field investigation of mercury in the McTier Creek watershed in 2006. The initial efforts of the investigation included the collection of extensive hydrologic and water-quality field data, along with the development of several hydrologic and water-quality models. This series of measured and modeled data forms the primary source of information for this investigation to assess the fate and transport of mercury within the McTier Creek watershed.

Recent advances in engineering topography mediated antibacterial surfaces

PubMed Central

Hasan, Jafar

2015-01-01

The tendency of bacterial cells to adhere and colonize a material surface leading to biofilm formation is a fundamental challenge underlying many different applications including microbial infections associated with biomedical devices and products. Although, bacterial attachment to surfaces has been extensively studied in the past, the effect of surface topography on bacteria–material interactions has received little attention until more recently. We review the recent progress in surface topography based approaches for engineering antibacterial surfaces. Biomimicry of antibacterial surfaces in nature is a popular strategy. Whereas earlier endeavors in the field aimed at minimizing cell attachment, more recent efforts have focused on developing bactericidal surfaces. However, not all such topography mediated bactericidal surfaces are necessarily cytocompatible thus underscoring the need for continued efforts for research in this area for developing antibacterial and yet cytocompatible surfaces for use in implantable biomedical applications. This mini-review provides a brief overview of the current strategies and challenges in the emerging field of topography mediated antibacterial surfaces. PMID:26372264

Recent advances in engineering topography mediated antibacterial surfaces

NASA Astrophysics Data System (ADS)

Hasan, Jafar; Chatterjee, Kaushik

2015-09-01

The tendency of bacterial cells to adhere and colonize a material surface leading to biofilm formation is a fundamental challenge underlying many different applications including microbial infections associated with biomedical devices and products. Although, bacterial attachment to surfaces has been extensively studied in the past, the effect of surface topography on bacteria-material interactions has received little attention until more recently. We review the recent progress in surface topography based approaches for engineering antibacterial surfaces. Biomimicry of antibacterial surfaces in nature is a popular strategy. Whereas earlier endeavors in the field aimed at minimizing cell attachment, more recent efforts have focused on developing bactericidal surfaces. However, not all such topography mediated bactericidal surfaces are necessarily cytocompatible thus underscoring the need for continued efforts for research in this area for developing antibacterial and yet cytocompatible surfaces for use in implantable biomedical applications. This mini-review provides a brief overview of the current strategies and challenges in the emerging field of topography mediated antibacterial surfaces.

Benefits of extensive recruitment effort persist during follow-ups and are consistent across age group and survey method. The TRAILS study

PubMed Central

2012-01-01

Background Extensive recruitment effort at baseline increases representativeness of study populations by decreasing non-response and associated bias. First, it is not known to what extent increased attrition occurs during subsequent measurement waves among subjects who were hard-to-recruit at baseline and what characteristics the hard-to-recruit dropouts have compared to the hard-to-recruit retainers. Second, it is unknown whether characteristics of hard-to-recruit responders in a prospective population based cohort study are similar across age group and survey method. Methods First, we compared first wave (T1) easy-to-recruit with hard-to-recruit responders of the TRacking Adolescents’ Individual Lives Survey (TRAILS), a prospective population based cohort study of Dutch (pre)adolescents (at first wave: n = 2230, mean age = 11.09 (SD 0.56), 50.8% girls), with regard to response rates at subsequent measurement waves. Second, easy-to-recruit and hard-to-recruit participants at the fourth TRAILS measurement wave (n = 1881, mean age = 19.1 (SD 0.60), 52.3% girls) were compared with fourth wave non-responders and earlier stage drop-outs on family composition, socioeconomic position (SEP), intelligence (IQ), education, sociometric status, substance use, and psychopathology. Results First, over 60% of the hard-to-recruit responders at the first wave were retained in the sample eight years later at the fourth measurement wave. Hard-to-recruit dropouts did not differ from hard-to-recruit retainers. Second, extensive recruitment efforts for the web based survey convinced a population of nineteen year olds with similar characteristics as the hard-to-recruit eleven year olds that were persuaded to participate in a school-based survey. Some characteristics associated with being hard-to-recruit (as compared to being easy-to-recruit) were more pronounced among non-responders, resembling the baseline situation (De Winter et al.2005). Conclusions First, extensive recruitment effort at the first assessment wave of a prospective population based cohort study has long lasting positive effects. Second, characteristics of hard-to-recruit responders are largely consistent across age groups and survey methods. PMID:22747967

Agriculture and Health Sectors Collaborate in Addressing Population Health

PubMed Central

Kaufman, Arthur; Boren, Jon; Koukel, Sonja; Ronquillo, Francisco; Davies, Cindy; Nkouaga, Carolina

2017-01-01

PURPOSE Population health is of growing importance in the changing health care environment. The Cooperative Extension Service, housed in each state’s land grant university, has a major impact on population health through its many community-based efforts, including the Supplemental Nutrition Assistance Program – Education (SNAP-Ed) nutrition programs, 4-H youth engagement, health and wellness education, and community development. Can the agricultural and health sectors, which usually operate in parallel, mostly unknown to each other, collaborate to address population health? We set out to provide an overview of the collaboration between the Cooperative Extension Service and the health sector in various states and describe a case study of 1 model as it developed in New Mexico. METHODS We conducted a literature review and personally contacted states in which the Cooperative Extension Service is collaborating on a “Health Extension” model with academic health centers or their health systems. We surveyed 6 states in which Health Extension models are being piloted as to their different approaches. For a case study of collaboration in New Mexico, we drew on interviews with the leadership of New Mexico State University’s Cooperative Extension Service in the College of Agricultural, Consumer and Environmental Sciences; the University of New Mexico (UNM) Health Science Center’s Office for Community Health; and the personal experiences of frontline Cooperative Extension agents and UNM Health Extension officers who collaborated on community projects. RESULTS A growing number of states are linking the agricultural Cooperative Extension Service with academic health centers and with the health care system. In New Mexico, the UNM academic health center has created “Health Extension Rural Offices” based on principles of the Cooperative Extension model. Today, these 2 systems are working collaboratively to address unmet population health needs in their communities. Nationally, the Cooperative Extension Service has formed a steering committee to guide its movement into the health arena. CONCLUSION Resources of the agricultural and health sectors offer communities complementary expertise and resources to address adverse population health outcomes. The collaboration between Cooperative Extension and the health sector is 1 manifestation of this emerging collaboration model termed Health Extension. Initial skepticism and protection of funding sources and leadership roles can be overcome with shared funding from new sources, shared priority setting and decision making, and the initiation of practical, collaborative projects that build personal relationships and trust. PMID:28893819

Stratigraphic Mapping of Intra-Crater Layered Deposits in Arabia Terra from High-Resolution Imaging and Stereo Topography

NASA Astrophysics Data System (ADS)

Annex, A. M.; Lewis, K. W.; Edwards, C. S.

2017-12-01

The Arabia Terra region of Mars, located in the mid-latitudes, hosts a number of crater basins with exposed sedimentary layers and buttes. Our work builds upon previous studies of these sites that suggest that the layers are formed of weakly lithified aeolian material with quasi-periodic expressions explained by changes in planetary orbital elements during formation (Lewis and Aharonson, 2014; Cadieux and Kah, 2015; Stack et al., 2013). In an effort to better understand differences in lateral continuity of these layers, both between and within basins, an extensive mapping effort was conducted on several sites in Arabia Terra with HiRISE stereo targets. Digital terrain models produced using the Ames Stereo Pipeline were mapped to derive bedding plane positions and orientations for each stratum using linear regression. Bed thicknesses were derived from differences in dip-corrected elevation between successive strata. Our study includes additional independent mapping within craters analyzed in previous studies, and expands mapping of these deposits to several new craters in the region unique to this effort. Our sample size in this study is large, including over 700 individually measured strata from multiple sections within each crater. Although bed thicknesses are generally tightly distributed around 12 meters, any changes within a sequence could represent variations in either the dominant forcing factors controlling deposition and/or changes in sedimentation rate. If craters contain correlative sequences, these types of changes could serve as marker horizons across the region with further mapping.

Quagga and zebra mussels: biology, impacts, and control

USGS Publications Warehouse

Nalepa, Thomas F.; Schloesser, Don W.; Nalepa, Thomas F.; Schloesser, Don W.

2013-01-01

Quagga and Zebra Mussels: Biology, Impacts, and Control, Second Edition provides a broad view of the zebra/quagga mussel issue, offering a historic perspective and up-to-date information on mussel research. Comprising 48 chapters, this second edition includes reviews of mussel morphology, physiology, and behavior. It details mussel distribution and spread in Europe and across North America, and examines policy and regulatory responses, management strategies, and mitigation efforts. In addition, this book provides extensive coverage of the impact of invasive mussel species on freshwater ecosystems, including effects on water clarity, phytoplankton, water quality, food web changes, and consequences to other aquatic fauna. It also reviews and offers new insights on how zebra and quagga mussels respond and adapt to varying environmental conditions. This new edition includes seven video clips that complement chapter text and, through visual documentation, provide a greater understanding of mussel behavior and distribution.

A comprehensive method for preliminary design optimization of axial gas turbine stages. II - Code verification

NASA Technical Reports Server (NTRS)

Jenkins, R. M.

1983-01-01

The present effort represents an extension of previous work wherein a calculation model for performing rapid pitchline optimization of axial gas turbine geometry, including blade profiles, is developed. The model requires no specification of geometric constraints. Output includes aerodynamic performance (adiabatic efficiency), hub-tip flow-path geometry, blade chords, and estimates of blade shape. Presented herein is a verification of the aerodynamic performance portion of the model, whereby detailed turbine test-rig data, including rig geometry, is input to the model to determine whether tested performance can be predicted. An array of seven (7) NASA single-stage axial gas turbine configurations is investigated, ranging in size from 0.6 kg/s to 63.8 kg/s mass flow and in specific work output from 153 J/g to 558 J/g at design (hot) conditions; stage loading factor ranges from 1.15 to 4.66.

An improved model for the Earth's gravity field

NASA Technical Reports Server (NTRS)

Tapley, B. D.; Shum, C. K.; Yuan, D. N.; Ries, J. C.; Schutz, B. E.

1989-01-01

An improved model for the Earth's gravity field, TEG-1, was determined using data sets from fourteen satellites, spanning the inclination ranges from 15 to 115 deg, and global surface gravity anomaly data. The satellite measurements include laser ranging data, Doppler range-rate data, and satellite-to-ocean radar altimeter data measurements, which include the direct height measurement and the differenced measurements at ground track crossings (crossover measurements). Also determined was another gravity field model, TEG-1S, which included all the data sets in TEG-1 with the exception of direct altimeter data. The effort has included an intense scrutiny of the gravity field solution methodology. The estimated parameters included geopotential coefficients complete to degree and order 50 with selected higher order coefficients, ocean and solid Earth tide parameters, Doppler tracking station coordinates and the quasi-stationary sea surface topography. Extensive error analysis and calibration of the formal covariance matrix indicate that the gravity field model is a significant improvement over previous models and can be used for general applications in geodesy.

BioC: a minimalist approach to interoperability for biomedical text processing

PubMed Central

Comeau, Donald C.; Islamaj Doğan, Rezarta; Ciccarese, Paolo; Cohen, Kevin Bretonnel; Krallinger, Martin; Leitner, Florian; Lu, Zhiyong; Peng, Yifan; Rinaldi, Fabio; Torii, Manabu; Valencia, Alfonso; Verspoor, Karin; Wiegers, Thomas C.; Wu, Cathy H.; Wilbur, W. John

2013-01-01

A vast amount of scientific information is encoded in natural language text, and the quantity of such text has become so great that it is no longer economically feasible to have a human as the first step in the search process. Natural language processing and text mining tools have become essential to facilitate the search for and extraction of information from text. This has led to vigorous research efforts to create useful tools and to create humanly labeled text corpora, which can be used to improve such tools. To encourage combining these efforts into larger, more powerful and more capable systems, a common interchange format to represent, store and exchange the data in a simple manner between different language processing systems and text mining tools is highly desirable. Here we propose a simple extensible mark-up language format to share text documents and annotations. The proposed annotation approach allows a large number of different annotations to be represented including sentences, tokens, parts of speech, named entities such as genes or diseases and relationships between named entities. In addition, we provide simple code to hold this data, read it from and write it back to extensible mark-up language files and perform some sample processing. We also describe completed as well as ongoing work to apply the approach in several directions. Code and data are available at http://bioc.sourceforge.net/. Database URL: http://bioc.sourceforge.net/ PMID:24048470

An annotated list of the mayflies, stoneflies, and caddisflies of the Sand Creek basin, Great Sand Dunes National Park and Preserve, Colorado, 2004 and 2005

USGS Publications Warehouse

Zuellig, Robert E.; Kondratieff, Boris C.; Ruiter, David E.; Thorp, Richard A.

2006-01-01

The U.S. Geological Survey, in conjunction with the Great Sand Dunes National Park and Preserve and its cooperators, did an extensive inventory of certain targeted aquatic-insect groups in the Sand Creek Basin, Great Sand Dunes National Park and Preserve, to establish a species list for future monitoring efforts. Study sites were established to monitor these groups following disturbance events. Such potential disturbances may include, but are not limited to, chemical treatment of perennial stream reaches to remove nonnative fishes and the subsequent reintroduction of native fish species, increased public use of backcountry habitat (such as hiking and fishing), and natural disturbances such as fire. This report is an annotated list of the mayflies, stoneflies, and caddisflies found in the Sand Creek Basin, Great Sand Dunes National Park and Preserve, 2004 and 2005. The primary objective of the study was to qualitatively inventory target aquatic-insect groups in perennial streams, and selected unique standing-water habitats, such as springs, and wetlands associated with the Sand Creek Basin. Efforts focused on documenting the presence of aquatic-insect species within the following taxonomic groups: Ephemeroptera (mayflies), Plecoptera (stoneflies), and Trichoptera (caddisflies). These insect orders were chosen because published species accounts, geographic distribution, and identification keys exist for many Colorado species. Given the extent of available information for these groups, there existed a potential for identifying new species and documenting range extensions of known species.

Hints for an extension of the early exercise premium formula for American options

NASA Astrophysics Data System (ADS)

Bermin, Hans-Peter; Kohatsu-Higa, Arturo; Perelló, Josep

2005-09-01

There exists a non-closed formula for the American put option price and non-trivial computations are required to solve it. Strong efforts have been made to propose efficient numerical techniques but few have strong mathematical reasoning to ascertain why they work well. We present an extension of the American put price aiming to catch weaknesses of the numerical methods based on their non-fulfillment of the smooth pasting condition.

Vaccine delivery management.

PubMed

Cheyne, J

1989-01-01

During the typical 12- to 18-month voyage of a vaccine from manufacturer to immunization site, many situations arise in which the cold chain may be interrupted. Extensive efforts have been made in the 1980s to ensure an uninterrupted cold chain through the use of improved equipment and better training of personnel. One important advance is the vaccine cold-chain monitor, which identifies weak spots in the cold chain and prevents the use of heat-damaged vaccine. Further improvements will require efforts by the recipient countries (e.g., better use of the private sector for transport and equipment management), by donor agencies (e.g., greater consideration of the operational and maintenance costs of the equipment selected and resolution of fuel shortages), and by industry (e.g., more appropriate packaging and pricing of vaccine, extension of the expiration period, and increased heat stability.

Development and Demonstration of a Magnesium-Intensive Vehicle Front-End Substructure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Logan, Stephen D.; Forsmark, Joy H.; Osborne, Richard

2016-07-01

This project is the final phase (designated Phase III) of an extensive, nine-year effort with the objectives of developing a knowledge base and enabling technologies for the design, fabrication and performance evaluation of magnesium-intensive automotive front-end substructures intended to partially or completely replace all-steel comparators, providing a weight savings approaching 50% of the baseline. Benefits of extensive vehicle weight reduction in terms of fuel economy increase, extended vehicle range, vehicle performance and commensurate reductions in greenhouse gas emissions are well known. An exemplary vehicle substructure considered by the project is illustrated in Figure 1, along with the exterior vehicle appearance.more » This unibody front-end “substructure” is one physical objective of the ultimate design and engineering aspects established at the outset of the larger collective effort.« less

Cognitive engineering models in space systems

NASA Technical Reports Server (NTRS)

Mitchell, Christine M.

1993-01-01

NASA space systems, including mission operations on the ground and in space, are complex, dynamic, predominantly automated systems in which the human operator is a supervisory controller. Models of cognitive functions in complex systems are needed to describe human performance and form the theoretical basis of operator workstation design, including displays, controls, and decision aids. Currently, there several candidate modeling methodologies. They include the Rasmussen abstraction/aggregation hierarchy and decision ladder, the goal-means network, the problem behavior graph, and the operator function model. The research conducted under the sponsorship of this grant focuses on the extension of the theoretical structure of the operator function model and its application to NASA Johnson mission operations and space station applications. The initial portion of this research consists of two parts. The first is a series of technical exchanges between NASA Johnson and Georgia Tech researchers. The purpose is to identify candidate applications for the current operator function model; prospects include mission operations and the Data Management System Testbed. The second portion will address extensions of the operator function model to tailor it to the specific needs of Johnson applications. At this point, we have accomplished two things. During a series of conversations with JSC researchers, we have defined the technical goal of the research supported by this grant to be the structural definition of the operator function model and its computer implementation, OFMspert. Both the OFM and OFMspert have matured to the point that they require infrastructure to facilitate use by researchers not involved in the evolution of the tools. The second accomplishment this year was the identification of the Payload Deployment and Retrieval System (PDRS) as a candidate system for the case study. In conjunction with government and contractor personnel in the Human-Computer Interaction Lab, the PDRS was identified as the most accessible system for the demonstration. Pursuant to this a PDRS simulation was obtained from the HCIL and an initial knowledge engineering effort was conducted to understand the operator's tasks in the PDRS application. The preliminary results of the knowledge engineering effort and an initial formulation of an operator function model (OFM) are contained in the appendices.

Solar thermal storage applications program

NASA Astrophysics Data System (ADS)

Peila, W. C.

1982-12-01

The efforts of the Storage Applications Program are reviewed. The program concentrated on the investigation of storage media and evaluation of storage methods. Extensive effort was given to experimental and analytical investigations of nitrate salts. Two tasks are the preliminary design of a 1200 MW/sub th/ system and the design, construction, operation, and evaluation of a subsystem research experiment, which utilized the same design. Some preliminary conclusions drawn from the subsystem research experiment are given.

Applying a Service-Oriented Architecture to Operational Flight Program Development

DTIC Science & Technology

2007-09-01

using two Java 2 Enterprise Edition (J2EE) Web servers. The weapon models were accessed using a SUN Microsystems Java Web Services Development Pack...Oriented Architectures 22 CROSSTALK The Journal of Defense Software Engineering September 2007 tion, and Spring/ Hibernate to provide the data access...tion since a major coding effort was avoided. The majority of the effort was tweaking pre-existing Java source code and editing of eXtensible Markup

Hindcasting of Storm Surges, Currents, and Waves at Lower Delaware Bay during Hurricane Isabel

NASA Astrophysics Data System (ADS)

Salehi, M.

2017-12-01

Hurricanes are a major threat to coastal communities and infrastructures including nuclear power plants located in low-lying coastal zones. In response, their sensitive elements should be protected by smart design to withstand against drastic impact of such natural phenomena. Accurate and reliable estimate of hurricane attributes is the first step to that effort. Numerical models have extensively grown over the past few years and are effective tools in modeling large scale natural events such as hurricane. The impact of low probability hurricanes on the lower Delaware Bay is investigated using dynamically coupled meteorological, hydrodynamic, and wave components of Delft3D software. Efforts are made to significantly reduce the computational overburden of performing such analysis for the industry, yet keeping the same level of accuracy at the area of study (AOS). The model is comprised of overall and nested domains. The overall model domain includes portion of Atlantic Ocean, Delaware, and Chesapeake bays. The nested model domain includes Delaware Bay, its floodplain, and portion of the continental shelf. This study is portion of a larger modeling effort to study the impact of low probability hurricanes on sensitive infrastructures located at the coastal zones prone to hurricane activity. The AOS is located on the east bank of Delaware Bay almost 16 miles upstream of its mouth. Model generated wind speed, significant wave height, water surface elevation, and current are calibrated for hurricane Isabel (2003). The model calibration results agreed reasonably well with field observations. Furthermore, sensitivity of surge and wave responses to various hurricane parameters was tested. In line with findings from other researchers, accuracy of wind field played a major role in hindcasting the hurricane attributes.

Challenges to the Lake

EPA Science Inventory

During the past decade we have extensively studied coastal ecosystems in the Great Lakes. Some research efforts have linked coastal receiving systems to conditions in their contributing watersheds; others have focused on developing invasive species detection and monitoring strat...

Description of Data Acquisition Efforts

DOT National Transportation Integrated Search

1999-09-01

As part of the overall strategy of refining and improving the existing transportation and air-quality modeling framework, the current project focuses extensively on acquiring disaggregate and reliable data for analysis. In this report, we discuss the...

Sex Trafficking, Violence Victimization, and Condom Non-Use Among Prostituted Women in Nicaragua

PubMed Central

Decker, Michele R.; Mack, Katelyn P.; Barrows, Jeffery J.; Silverman, Jay G.

2013-01-01

Synopsis Prostituted women report disempowerment-related barriers to condom use, extensive violence victimization and trafficking experiences; findings indicate that disempowerment must be addressed within STI/HIV prevention efforts. PMID:19577234

Analysis of VASCAR

DOT National Transportation Integrated Search

1991-05-01

This study is part of an effort by the National Highway Traffic Safety : Administration (NHTSA) to determine the accuracy of the VASCAR-plus speed measurement device. VASCAR-plus is used extensively for speed law enforcement by state and local police...

Bird communities of natural and modified habitats in Panama

USGS Publications Warehouse

Petit, L.J.; Petit, D.R.; Christian, D.G.; Powell, Hugo D.W.

1999-01-01

Only a small proportion of land can realistically be protected as nature reserves and thus conservation efforts also must focus on the ecological value of agroecosystems and developed areas surrounding nature reserves. In this study, avian communities were surveyed in 11 habitat types in central Panama, across a gradient from extensive forest to intensive agricultural land uses, to examine patterns of species richness and abundance and community composition. Wooded habitats, including extensive and fragmented forests, shade coffee plantations, and residential areas supported the most species and individuals. Nearctic-Neotropical migratory species were most numerous in lowland forest fragments, shade coffee, and residential areas. Introduced Pinus caribbea and sugar cane plantations supported the fewest species compared to all other habitats. Cattle pastures left fallow for less than two years supported more than twice as many total species as actively grazed pastures, such that species richness in fallow pastures was similar to that found in wooded habitats. Community similarities were relatively low among all habitat types (none exceeding the observed 65% similarity between extensive and fragmented lowland forests), but communities in shade coffee and residential areas were 43% and 54% similar to lowland forest fragments, respectively. Fallow pastures and residential areas shared 60% of their species. Bird communities in shade coffee and residential areas were characterized by higher proportions of frugivorous and nectarivorous species than in native forests. These same guilds also were better represented in fallow than in grazed pastures. Raptors and piscivorous species were most prevalent in cattle pastures and rice fields. These results, though based upon only species richness and abundance, demonstrate that many human-altered habitats have potential ecological value for birds, and conservation efforts in tropical areas should focus greater attention on enhancement of agricultural and developed lands as wildlife habitat. To understand the true conservation value of these modified lands will require examination not only of numbers but also of the types of species supported by these habitats, their reproductive output and survival rates.

Thermal Optimization of an On-Orbit Long Duration Cryogenic Propellant Depot

NASA Technical Reports Server (NTRS)

Honour, Ryan; Kwas, Robert; O'Neil, Gary; Kutter, Gary

2012-01-01

A Cryogenic Propellant Depot (CPD) operating in Low Earth Orbit (LEO) could provide many near term benefits to NASA's space exploration efforts. These benefits include elongation/extension of spacecraft missions and requirement reduction of launch vehicle up-mass. Some of the challenges include controlling cryogenic propellant evaporation and managing the high costs and long schedules associated with the new development of spacecraft hardware. This paper describes a conceptual CPD design that is thermally optimized to achieve extremely low propellant boil-off rates. The CPD design is based on existing launch vehicle architecture, and its thermal optimization is achieved using current passive thermal control technology. Results from an integrated thermal model are presented showing that this conceptual CPD design can achieve propellant boil-off rates well under 0.05% per day, even when subjected to the LEO thermal environment.

[Climate changes, floods, and health consequences].

PubMed

Michelozzi, Paola; de' Donato, Francesca

2014-02-01

In the European Region, floods are the most common natural disaster, causing extensive damage and disruption. In Italy, it has been estimated that over 68% of municipalities are at high hydrogeological risk and with the recent intense rainfall events local populations have been facing severe disruptions. The health consequences of floods are wide ranging and are dependent upon the vulnerability of the environment and the local population. Health effects can be a direct or indirect consequence of flooding. The immediate health impacts of floods include drowning, heart attacks, injuries and hypothermia. The indirect effects include, injuries and infections, water-borne infectious disease, mental health problems, respiratory disease and allergies in both the medium and long term after a flood. Future efforts should be addressed to integrate health preparedness and prevention measures into emergency flood plans and hydrological warning systems.

Thermal Optimization and Assessment of a Long Duration Cryogenic Propellant Depot

NASA Technical Reports Server (NTRS)

Honour, Ryan; Kwas, Robert; O'Neil, Gary; Kutter, Bernard

2012-01-01

A Cryogenic Propellant Depot (CPD) operating in Low Earth Orbit (LEO) could provide many near term benefits to NASA space exploration efforts. These benefits include elongation/extension of spacecraft missions and reduction of launch vehicle up-mass requirements. Some of the challenges include controlling cryogenic propellant evaporation and managing the high costs and long schedules associated with new spacecraft hardware development. This paper describes a conceptual CPD design that is thermally optimized to achieve extremely low propellant boil-off rates. The CPD design is based on existing launch vehicle architecture, and its thermal optimization is achieved using current passive thermal control technology. Results from an integrated thermal model are presented showing that this conceptual CPD design can achieve propellant boil-off rates well under 0.05% per day, even when subjected to the LEO thermal environment.

Measurements of Gases and Aerosols during 2010Cal-Mex

NASA Astrophysics Data System (ADS)

Zheng, J.; Zhang, R.; Molina, L.

2012-04-01

The major goal of the collaborative Cal-Mex 2010 research project is to assess the sources and processing of emissions along the California-Mexico border region and their effects on regional air quality and climate in order to provide scientific information to decision makers of both nations when addressing these two inter-related issues. During the Cal-Mex 2010 field study, the TAMU teams have collected extensive data sets from Tijuana/San Diego border, including volatile organic compounds (VOCs), gaseous sulfuric acid (H2SO4) and a suite set of physical and chemical parameters of aerosols. This comprehensive data set requires additional effort to process and analyze the measurements of gases and aerosols during Cal-Mex 2010. In this talk, preliminary data analysis of gases and aerosols will be presented, including VOCs and particle mixing states, morphology, and effective densities.

A coactive interdisciplinary research program with NASA

NASA Technical Reports Server (NTRS)

Rouse, J. W., Jr.

1972-01-01

The applications area of the Texas A&M University remote sensing program consists of a series of coactive projects with NASA/MSC personnel. In each case, the Remote Sensing Center has served to complement and enhance the research capability within the Manned Spacecraft Center. In addition to the applications study area, the Texas A&M University program includes coordinated projects in sensors and data analysis. Under the sensors area, an extensive experimental study of microwave radiometry for soil moisture determination established the effect of soil moisture on the measured brightness temperature for several different soil types. The data analysis area included a project which ERTS-A and Skylab data were simulated using aircraft multispectral scanner measurements at two altitudes. This effort resulted in development of a library of computer programs which provides an operational capability in classification analysis of multispectral data.

Electrochemical reverse engineering: A systems-level tool to probe the redox-based molecular communication of biology.

PubMed

Li, Jinyang; Liu, Yi; Kim, Eunkyoung; March, John C; Bentley, William E; Payne, Gregory F

2017-04-01

The intestine is the site of digestion and forms a critical interface between the host and the outside world. This interface is composed of host epithelium and a complex microbiota which is "connected" through an extensive web of chemical and biological interactions that determine the balance between health and disease for the host. This biology and the associated chemical dialogues occur within a context of a steep oxygen gradient that provides the driving force for a variety of reduction and oxidation (redox) reactions. While some redox couples (e.g., catecholics) can spontaneously exchange electrons, many others are kinetically "insulated" (e.g., biothiols) allowing the biology to set and control their redox states far from equilibrium. It is well known that within cells, such non-equilibrated redox couples are poised to transfer electrons to perform reactions essential to immune defense (e.g., transfer from NADH to O 2 for reactive oxygen species, ROS, generation) and protection from such oxidative stresses (e.g., glutathione-based reduction of ROS). More recently, it has been recognized that some of these redox-active species (e.g., H 2 O 2 ) cross membranes and diffuse into the extracellular environment including lumen to transmit redox information that is received by atomically-specific receptors (e.g., cysteine-based sulfur switches) that regulate biological functions. Thus, redox has emerged as an important modality in the chemical signaling that occurs in the intestine and there have been emerging efforts to develop the experimental tools needed to probe this modality. We suggest that electrochemistry provides a unique tool to experimentally probe redox interactions at a systems level. Importantly, electrochemistry offers the potential to enlist the extensive theories established in signal processing in an effort to "reverse engineer" the molecular communication occurring in this complex biological system. Here, we review our efforts to develop this electrochemical tool for in vitro redox-probing. Copyright © 2017 Elsevier Inc. All rights reserved.

IYA2009 Programs in Canada: The "Big Picture” In June, 2008

NASA Astrophysics Data System (ADS)

Hesser, James E.; Lane, D.; Langill, P. P. L.; Percy, J. R.; Canada Committee, IYA

2008-05-01

The Canadian partnership--Royal Astronomical Society of Canada (RASC), Fédération des astronomes amateurs du Québec (FAAQ) and Canadian Astronomical Society (CASCA)--is implementing elements designed to offer an engaging astronomy experience to every Canadian during 2009. Our goals for all themes envision creating long-lasting impacts, especially in the education and inspiration of youth. Wherever possible we seek to leverage and extend existing programs, and we aim to provide materials in both English and French. To make IYA2009 successful, both the RASC and FAAQ have committed significant funds over and above their extensive in-kind contributions of volunteer time. Through The Galileo Moment theme we aim to get more than one million Canadians to look through a telescope, or participate in cultural and outreach events that bring a strong sense of personal astronomical discovery. An Astronomy Kit of physical and virtual components is under development. A partnership led by Cape Breton University faculty proposes extensive participation by Canada's Aboriginal Communities, including a series of activities designed to bring elders and youth together. Reinvigoration of the RASC's long-standing efforts to create Dark Sky Preserves is another cross-cutting theme. Outreach programs of Canada's major Planetaria and Science Centres, a National Astronomy Lecture Series, as well as partnerships with Arts and Cultural Organizations, offer hopes of reaching both traditional and non-traditional audiences in fun, engaging ways. Individual volunteer efforts are emerging to implement From the Earth to the Universe astronomical image exhibits from material developed by both IAU and Canadian curatorial teams in high-traffic locales. Efforts are underway to secure commemorative stamps and coins, with recent encouraging news about the former. The Canadian Space Agency has agreed to launch in 2010 a CD/DVD with names of the Canadians who register their Galileo Moment experience. Fund raising is underway in earnest. See www.astronomy2009.ca for current information.

IYA2009 Programmes in Canada: The ``Big Picture'' in June 2008

NASA Astrophysics Data System (ADS)

Hesser, J. E.; Lane, D.; Langill, P. P.; Percy, J. R.

2008-11-01

The Canadian partnership---Royal Astronomical Society of Canada (RASC), Fédération des astronomes amateurs du Québec (FAAQ), and Canadian Astronomical Society (CASCA)---is implementing elements designed to offer an engaging astronomy experience to every Canadian during 2009. Our goals for all themes envision creating long-lasting impacts, especially in the education and inspiration of youth. Wherever possible we seek to leverage and extend existing programmes, and we aim to provide materials in both English and French. To make IYA2009 successful, both the RASC and FAAQ have committed significant funds over and above their extensive in-kind contributions of volunteer time. Through the `Galileo Moment' theme we aim to get more than one million Canadians to look through a telescope, or participate in cultural and outreach events that bring a strong sense of personal astronomical discovery. An Astronomy Kit of physical and/or virtual components is under development. A partnership led by Cape Breton University faculty proposes extensive participation by Canada's Aboriginal Communities, including a series of activities designed to bring elders and youth together. Reinvigoration of the RASC's long-standing efforts to create Dark Sky Preserves is another cross-cutting theme. Outreach programmes of Canada's major planetaria and science centres, a national astronomy lecture series, as well as partnerships with arts and cultural organizations, offer hopes of reaching both traditional and non-traditional audiences in fun, engaging ways. Individual volunteer efforts are emerging to implement in high-traffic locales From the Earth to the Universe astronomical image exhibits from material developed by both IAU and Canadian curatorial teams. Our proposal for commemorative stamps has been accepted, and efforts are underway to secure commemorative coins, as well. The Canadian Space Agency has agreed to launch in 2010 a DVD with names of the Canadians who register their Galileo Moment experience. Fund raising is underway in earnest. See http://www.astronomy2009.ca for current information.

Development and validation of an automated operational modal analysis algorithm for vibration-based monitoring and tensile load estimation

NASA Astrophysics Data System (ADS)

Rainieri, Carlo; Fabbrocino, Giovanni

2015-08-01

In the last few decades large research efforts have been devoted to the development of methods for automated detection of damage and degradation phenomena at an early stage. Modal-based damage detection techniques are well-established methods, whose effectiveness for Level 1 (existence) and Level 2 (location) damage detection is demonstrated by several studies. The indirect estimation of tensile loads in cables and tie-rods is another attractive application of vibration measurements. It provides interesting opportunities for cheap and fast quality checks in the construction phase, as well as for safety evaluations and structural maintenance over the structure lifespan. However, the lack of automated modal identification and tracking procedures has been for long a relevant drawback to the extensive application of the above-mentioned techniques in the engineering practice. An increasing number of field applications of modal-based structural health and performance assessment are appearing after the development of several automated output-only modal identification procedures in the last few years. Nevertheless, additional efforts are still needed to enhance the robustness of automated modal identification algorithms, control the computational efforts and improve the reliability of modal parameter estimates (in particular, damping). This paper deals with an original algorithm for automated output-only modal parameter estimation. Particular emphasis is given to the extensive validation of the algorithm based on simulated and real datasets in view of continuous monitoring applications. The results point out that the algorithm is fairly robust and demonstrate its ability to provide accurate and precise estimates of the modal parameters, including damping ratios. As a result, it has been used to develop systems for vibration-based estimation of tensile loads in cables and tie-rods. Promising results have been achieved for non-destructive testing as well as continuous monitoring purposes. They are documented in the last sections of the paper.

The future of bibliographic standards in a networked information environment

NASA Technical Reports Server (NTRS)

1997-01-01

The main mission of the CENDI Cataloging Working Group is to provide guidelines for cataloging practices that support the sharing of database records among the CENDI agencies, and that incorporate principles based on cost effectiveness and efficiency. Recent efforts include the extension of COSATI Guidelines for the Cataloging of Technical Reports to include non-print materials, and the mapping of each agency's export file structure to USMARC. Of primary importance is the impact of electronic documents and the distributed nature of the networked information environment. Topics discussed during the workshop include the following: Trade-offs in Cataloging and Indexing Internet Information; The Impact on Current and Future Standards; A Look at WWW Metadata Initiatives; Standards for Electronic Journals; The Present and Future Search Engines; The Roles for Text Analysis Software; Advanced Search Engine Meets Metathesaurus; Locator Schemes for Internet Resources; Identifying and Cataloging Web Document Types; In Search of a New Bibliographic Record. The videos in this set include viewgraphs of charts and related materials of the workshop.

Taking Innovation To Scale In Primary Care Practices: The Functions Of Health Care Extension

PubMed Central

Ono, Sarah S.; Crabtree, Benjamin F.; Hemler, Jennifer R.; Balasubramanian, Bijal A.; Edwards, Samuel T.; Green, Larry A.; Kaufman, Arthur; Solberg, Leif I.; Miller, William L.; Woodson, Tanisha Tate; Sweeney, Shannon M.; Cohen, Deborah J.

2018-01-01

Health care extension is an approach to providing external support to primary care practices with the aim of diffusing innovation. EvidenceNOW was launched to rapidly disseminate and implement evidence-based guidelines for cardiovascular preventive care in the primary care setting. Seven regional grantee cooperatives provided the foundational elements of health care extension—technological and quality improvement support, practice capacity building, and linking with community resources—to more than two hundred primary care practices in each region. This article describes how the cooperatives varied in their approaches to extension and provides early empirical evidence that health care extension is a feasible and potentially useful approach for providing quality improvement support to primary care practices. With investment, health care extension may be an effective platform for federal and state quality improvement efforts to create economies of scale and provide practices with more robust and coordinated support services. PMID:29401016

Biomass power for rural development. Technical progress report, January 1--March 31, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

Brief progress reports are presented on the following tasks: design packages for retrofits at the Dunkirk Station; fuel supply and site development plans; major equipment guarantees and project risk sharing; power production commitment; power plant site plan, construction and environmental permits; and experimental strategies for system evaluation. The paper then discusses in more detail the following: feedstock development efforts; clone-site testing and genetic studies; and efforts at outreach, extension and technology transfer.

Reduction of Tunnel Dynamics at the National Transonic Facility (Invited)

NASA Technical Reports Server (NTRS)

Kilgore, W. A.; Balakrishna, S.; Butler, D. H.

2001-01-01

This paper describes the results of recent efforts to reduce the tunnel dynamics at the National Transonic Facility. The results presented describe the findings of an extensive data analysis, the proposed solutions to reduce dynamics and the results of implementing these solutions. These results show a 90% reduction in the dynamics around the model support structure and a small impact on reducing model dynamics. Also presented are several continuing efforts to further reduce dynamics.

Domain Wall Evolution in Phase Transforming Oxides

DTIC Science & Technology

2015-01-14

configumtions under driving forces (e.g. changes in temperature and electric fields) in an effort to: 1) understand the underlying linkage between -1...configurations under driving forces (e.g. changes in temperature and electric fields) in an effort to: 1) understand the underlying linkage between...Extensive domain wall motion and deaging resistance in morphotropic 0.55Bi(Ni1/2Ti1/2)O3–0.45PbTiO3 polycrystalline ferroelectrics, Applied Physics Letters

[Sincerity of effort: isokinetic evaluation of knee extension].

PubMed

Colombo, R; Demaiti, G; Sartorio, F; Orlandini, D; Vercelli, S; Ferriero, G

2008-01-01

The aim of this study was to find a reliable method to evaluate the sincerity of the muscular maximal effort performed in a dynamometric isokinetic test of knee flexion-extension. The coefficient of variation of the peak torque (CV) and 3 new indices were analysed: (1) the average coefficient of variation calculated on the complete peak torque curve (CVM); (2) the slope of the regression line in an endurance test (PRR); (3) the correlation coefficient of the peak torques in the same endurance test (CCR). Twenty healthy subjects underwent assessment in two different trials, maximal (MX) and 50% submaximal (SMX), with 20 minutes of rest between trials. Each trial consisted of 4 tests, each of 3 repetitions, at angular speed of 30, 180, 30, and 180 degrees/s, respectively, and 1 test of 15 repetitions at 240 degrees/s. Our findings confirmed the ability of CV to detect a high percentage of sincere efforts: at 30 degrees/s Sensibility (Sns)=100% and Specificity (Spc)=70%; at 180 degrees/s Sns=75%, Spc=95%. The 3 new indices here proposed showed high characteristics of Sns and Spc, generally better than those of CV. CVM showed at 180 degrees/s Sns=90% and Spc=100%, while at 30 degrees/s Sns=90%, Spc=75%. PRR was the best index identifying all the efforts, except one (Sns=100%, Spc=95%). The CCR coefficient showed Sns and Spc values both of 90%.

Major advances in extension education programs in dairy production.

PubMed

Chase, L E; Ely, L O; Hutjens, M F

2006-04-01

The dairy industry has seen structural changes in the last 25 yr that have an impact on extension programming. The number of cows in the United States has decreased by 17%, whereas the number of dairy farms has decreased by 74%. The average milk production per cow has increased from 5,394 to 8,599 kg/lactation. Even though there are fewer farms, dairy farm managers are asking for more specific and targeted information. The extension resources available have also decreased during this period. Because of these changes, shifts have taken place in extension programming and staffing. A key change has been a shift to subject matter-targeted programs and workshops. Extension has also incorporated and expanded use of the Internet. Discussion groups, subject matter courses, and searchable databases are examples of Internet use. There will be continuing shifts in the demographics of the US dairy industry that will influence future extension efforts. It is also probable that fewer extension professionals will be available to provide programming due to changes in funding sources at national, state, and local levels. Future shifts in extension programming will be needed to provide the information needs of the industry with a smaller number of extension workers.

Overview of ten-year operation of the superconducting linear accelerator at the Spallation Neutron Source

NASA Astrophysics Data System (ADS)

Kim, S.-H.; Afanador, R.; Barnhart, D. L.; Crofford, M.; Degraff, B. D.; Doleans, M.; Galambos, J.; Gold, S. W.; Howell, M. P.; Mammosser, J.; McMahan, C. J.; Neustadt, T. S.; Peters, C.; Saunders, J. W.; Strong, W. H.; Vandygriff, D. J.; Vandygriff, D. M.

2017-04-01

The Spallation Neutron Source (SNS) has acquired extensive operational experience of a pulsed proton superconducting linear accelerator (SCL) as a user facility. Numerous lessons have been learned in its first 10 years operation to achieve a stable and reliable operation of the SCL. In this paper, an overview of the SNS SCL design, qualification of superconducting radio frequency (SRF) cavities and ancillary subsystems, an overview of the SNS cryogenic system, the SCL operation including SCL output energy history and downtime statistics, performance stability of the SRF cavities, efforts for SRF cavity performance recovery and improvement at the SNS, and maintenance activities for cryomodules are introduced.

Retail food environments research: Promising future with more work to be done.

PubMed

Fuller, Daniel; Engler-Stringer, Rachel; Muhajarine, Nazeem

2016-06-09

As members of the scientific committee for the Food Environments in Canada conference, we reflect on the current state of food environments research in Canada. We are very encouraged that the field is growing and there have been many collaborative efforts to link researchers in Canada, including the 2015 Food Environments in Canada Symposium and Workshop. We believe there are 5 key challenges the field will need to collectively address: theory and causality; replication and extension; consideration of rural, northern and vulnerable populations; policy analysis; and intervention research. In addressing the challenges, we look forward to working together to conduct more sophisticated, complex and community-driven food environments research in the future.

Overview of ten-year operation of the superconducting linear accelerator at the Spallation Neutron Source

DOE PAGES

Kim, Sang-Ho; Afanador, Ralph; Barnhart, Debra L.; ...

2017-02-04

The Spallation Neutron Source (SNS) has acquired extensive operational experience of a pulsed proton superconducting linear accelerator (SCL) as a user facility. Numerous lessons have been learned in its first 10 years operation to achieve a stable and reliable operation of the SCL. In this paper, an overview of the SNS SCL design, qualification of superconducting radio frequency (SRF) cavities and ancillary subsystems, an overview of the SNS cryogenic system, the SCL operation including SCL output energy history and downtime statistics, performance stability of the SRF cavities, efforts for SRF cavity performance recovery and improvement at the SNS, and maintenancemore » activities for cryomodules are introduced.« less

Fixed gain and adaptive techniques for rotorcraft vibration control

NASA Technical Reports Server (NTRS)

Roy, R. H.; Saberi, H. A.; Walker, R. A.

1985-01-01

The results of an analysis effort performed to demonstrate the feasibility of employing approximate dynamical models and frequency shaped cost functional control law desgin techniques for helicopter vibration suppression are presented. Both fixed gain and adaptive control designs based on linear second order dynamical models were implemented in a detailed Rotor Systems Research Aircraft (RSRA) simulation to validate these active vibration suppression control laws. Approximate models of fuselage flexibility were included in the RSRA simulation in order to more accurately characterize the structural dynamics. The results for both the fixed gain and adaptive approaches are promising and provide a foundation for pursuing further validation in more extensive simulation studies and in wind tunnel and/or flight tests.

Numerical aerodynamic simulation facility. Preliminary study extension

NASA Technical Reports Server (NTRS)

1978-01-01

The production of an optimized design of key elements of the candidate facility was the primary objective of this report. This was accomplished by effort in the following tasks: (1) to further develop, optimize and describe the function description of the custom hardware; (2) to delineate trade off areas between performance, reliability, availability, serviceability, and programmability; (3) to develop metrics and models for validation of the candidate systems performance; (4) to conduct a functional simulation of the system design; (5) to perform a reliability analysis of the system design; and (6) to develop the software specifications to include a user level high level programming language, a correspondence between the programming language and instruction set and outline the operation system requirements.

Overview of ten-year operation of the superconducting linear accelerator at the Spallation Neutron Source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Sang-Ho; Afanador, Ralph; Barnhart, Debra L.

The Spallation Neutron Source (SNS) has acquired extensive operational experience of a pulsed proton superconducting linear accelerator (SCL) as a user facility. Numerous lessons have been learned in its first 10 years operation to achieve a stable and reliable operation of the SCL. In this paper, an overview of the SNS SCL design, qualification of superconducting radio frequency (SRF) cavities and ancillary subsystems, an overview of the SNS cryogenic system, the SCL operation including SCL output energy history and downtime statistics, performance stability of the SRF cavities, efforts for SRF cavity performance recovery and improvement at the SNS, and maintenancemore » activities for cryomodules are introduced.« less

Utilizing grassroots workers in family planning programs in India: prospects and problems.

PubMed

Mani, S B

1991-01-01

In order to rapidly expand the network of delivery systems and speed up the process of acceptance of family planning messages and methods, a shift took place in the Indian family planning program from the bureaucratic "clinical" approach to the people oriented "extension" approach. As a result, there is an increasing emphasis on moving the family planning efforts closer to the grassroots level. A key methodological issue centers on the proper selection, cultural acceptability, and the effectiveness of the grassroots workers who are to be trained and through whom family planning motivational messages and methods are to be introduced. The Indian government, from time to time, has trained and utilized different groups of grassroots workers in its family planning promotional efforts. Anthropological field studies were conducted in two different regions in India to examine the potential and actual roles of two groups of grassroots workers--opinion leaders and traditional birth attendants--in the delivery of family planning services in the rural areas. These studies revealed that while the traditional birth attendants can be trained and utilized to a limited extent in promoting family planning efforts, especially to the eligible female clients, the role of the opinion leaders in such efforts is at best questionable. Based on these field studies, cultural and technical (including bureaucratic) problems in training and utilizing opinion leaders and traditional birth attendants are explored in detail. Modifications in the training program strategies are suggested to improve and expand the family planning delivery system in rural India.

Policy Implications of Air Quality Research

NASA Astrophysics Data System (ADS)

Sheinbaum, C.

2004-12-01

While an integrated assessment approach will be required to achieve and sustain improvements in the air quality of Mexico City Metropolitan Area's (MCMA), policy strategies must be based on a solid understanding of the pollutant emissions and atmospheric processes that lead to unacceptable levels of air pollution. The required level of understanding can only be achieved by comprehensive atmospheric measurements followed by a coordinated atmospheric modeling program. The innovative, two-phase atmospheric measurement program, which was a collaborative effort between Massachusetts Institute of Technology and the Mexican Metropolitan Environmental Commission, with exploratory measurements in February 2002 and extensive measurements from late March through early May of 2003, was an important step towards meeting these requirements. Although the extensive data sets from the two measurement programs are still being analyzed by the investigators, their preliminary analysis efforts have yielded important insights into the nature and extent of air pollution problem in the MCMA, which in turn will have important policy implications.

Assumed--stress hybrid elements with drilling degrees of freedom for nonlinear analysis of composite structures

NASA Technical Reports Server (NTRS)

Knight, Norman F., Jr. (Principal Investigator)

1996-01-01

The goal of this research project is to develop assumed-stress hybrid elements with rotational degrees of freedom for analyzing composite structures. During the first year of the three-year activity, the effort was directed to further assess the AQ4 shell element and its extensions to buckling and free vibration problems. In addition, the development of a compatible 2-node beam element was to be accomplished. The extensions and new developments were implemented in the Computational Structural Mechanics Testbed COMET. An assessment was performed to verify the implementation and to assess the performance of these elements in terms of accuracy. During the second and third years, extensions to geometrically nonlinear problems were developed and tested. This effort involved working with the nonlinear solution strategy as well as the nonlinear formulation for the elements. This research has resulted in the development and implementation of two additional element processors (ES22 for the beam element and ES24 for the shell elements) in COMET. The software was developed using a SUN workstation and has been ported to the NASA Langley Convex named blackbird. Both element processors are now part of the baseline version of COMET.

An iterative and targeted sampling design informed by habitat suitability models for detecting focal plant species over extensive areas.

PubMed

Wang, Ophelia; Zachmann, Luke J; Sesnie, Steven E; Olsson, Aaryn D; Dickson, Brett G

2014-01-01

Prioritizing areas for management of non-native invasive plants is critical, as invasive plants can negatively impact plant community structure. Extensive and multi-jurisdictional inventories are essential to prioritize actions aimed at mitigating the impact of invasions and changes in disturbance regimes. However, previous work devoted little effort to devising sampling methods sufficient to assess the scope of multi-jurisdictional invasion over extensive areas. Here we describe a large-scale sampling design that used species occurrence data, habitat suitability models, and iterative and targeted sampling efforts to sample five species and satisfy two key management objectives: 1) detecting non-native invasive plants across previously unsampled gradients, and 2) characterizing the distribution of non-native invasive plants at landscape to regional scales. Habitat suitability models of five species were based on occurrence records and predictor variables derived from topography, precipitation, and remotely sensed data. We stratified and established field sampling locations according to predicted habitat suitability and phenological, substrate, and logistical constraints. Across previously unvisited areas, we detected at least one of our focal species on 77% of plots. In turn, we used detections from 2011 to improve habitat suitability models and sampling efforts in 2012, as well as additional spatial constraints to increase detections. These modifications resulted in a 96% detection rate at plots. The range of habitat suitability values that identified highly and less suitable habitats and their environmental conditions corresponded to field detections with mixed levels of agreement. Our study demonstrated that an iterative and targeted sampling framework can address sampling bias, reduce time costs, and increase detections. Other studies can extend the sampling framework to develop methods in other ecosystems to provide detection data. The sampling methods implemented here provide a meaningful tool when understanding the potential distribution and habitat of species over multi-jurisdictional and extensive areas is needed for achieving management objectives.

An Iterative and Targeted Sampling Design Informed by Habitat Suitability Models for Detecting Focal Plant Species over Extensive Areas

PubMed Central

Wang, Ophelia; Zachmann, Luke J.; Sesnie, Steven E.; Olsson, Aaryn D.; Dickson, Brett G.

2014-01-01

Prioritizing areas for management of non-native invasive plants is critical, as invasive plants can negatively impact plant community structure. Extensive and multi-jurisdictional inventories are essential to prioritize actions aimed at mitigating the impact of invasions and changes in disturbance regimes. However, previous work devoted little effort to devising sampling methods sufficient to assess the scope of multi-jurisdictional invasion over extensive areas. Here we describe a large-scale sampling design that used species occurrence data, habitat suitability models, and iterative and targeted sampling efforts to sample five species and satisfy two key management objectives: 1) detecting non-native invasive plants across previously unsampled gradients, and 2) characterizing the distribution of non-native invasive plants at landscape to regional scales. Habitat suitability models of five species were based on occurrence records and predictor variables derived from topography, precipitation, and remotely sensed data. We stratified and established field sampling locations according to predicted habitat suitability and phenological, substrate, and logistical constraints. Across previously unvisited areas, we detected at least one of our focal species on 77% of plots. In turn, we used detections from 2011 to improve habitat suitability models and sampling efforts in 2012, as well as additional spatial constraints to increase detections. These modifications resulted in a 96% detection rate at plots. The range of habitat suitability values that identified highly and less suitable habitats and their environmental conditions corresponded to field detections with mixed levels of agreement. Our study demonstrated that an iterative and targeted sampling framework can address sampling bias, reduce time costs, and increase detections. Other studies can extend the sampling framework to develop methods in other ecosystems to provide detection data. The sampling methods implemented here provide a meaningful tool when understanding the potential distribution and habitat of species over multi-jurisdictional and extensive areas is needed for achieving management objectives. PMID:25019621

Improving Science Communication and Engaging the Public in Astronomy and Nature

NASA Astrophysics Data System (ADS)

Arion, Douglas N.

2016-01-01

A partnershipship between Carthage College and the Appalachian Mountain Club has delivered a successful public education and outreach program that merges natural environment topics and astronomy. Over the four years of activity, over 25,000 people have received programming. The effort has trained nature educators, permanent and seasonal AMC staff, and undergraduate physics and astronomy students to integrate diverse topical material and deliver high quality programming to the lay public. Unique to the program is the holistic nature of the material delivered - an 'atypical' astronomy program. Linking observable characteristics of the natural world with astronomical history and phenomena, and emphasizing the unique sequence of events that have led to human life on Earth, the program has changed attitudes and behaviors among the public participants. Successful interventions have included hands-on observing programs (day and night) that link nature content to the observed objects; table-talk presentations on nature/astronomy topics; dark skies preservation workshops; and hands-on activities developed for younger audiences, including schools, camps, and family groups. An extensive evaluation and assessment effort managed by a leading sociologist has demonstrated the effectiveness of the approach, and contributed to continuous improvement in the program content and methods. This work was supported in part by NSF Grant 1432662.

Pathobiology and genetics of neural tube defects.

PubMed

Finnell, Richard H; Gould, Amy; Spiegelstein, Ofer

2003-01-01

Neural tube defects (NTDs), including spina bifida and anencephaly, are common congenital malformations that occur when the neural tube fails to achieve proper closure during early embryogenesis. Based on epidemiological and clinical data obtained over the last few decades, it is apparent that these multifactorial defects have a significant genetic component to their etiology that interacts with specific environmental risk factors. The purpose of this review article is to synthesize the existing literature on the genetic factors contributing to NTD risk. To date, there is evidence that closure of the mammalian neural tube initiates and fuses intermittently at four discrete locations. Disruption of this process at any of these four sites may lead to an NTD, possibly arising through closure site-specific genetic mechanisms. Candidate genes involved in neural tube closure include genes of the folate metabolic pathway, as well as those involved in folate transport. Although extensive efforts have focused on elucidating the genetic risk factors contributing to the etiology of NTDs, the population burden for these malformations remains unknown. One group at high risk for having children with NTDs is epileptic women receiving antiepileptic medications during pregnancy. Efforts to better understand the genetic factors that may contribute to their heightened risk, as well as the pathogenesis of neural tube closure defects, are reviewed herein.

Irma 5.2 multi-sensor signature prediction model

NASA Astrophysics Data System (ADS)

Savage, James; Coker, Charles; Thai, Bea; Aboutalib, Omar; Chow, Anthony; Yamaoka, Neil; Kim, Charles

2007-04-01

The Irma synthetic signature prediction code is being developed by the Munitions Directorate of the Air Force Research Laboratory (AFRL/MN) to facilitate the research and development of multi-sensor systems. There are over 130 users within the Department of Defense, NASA, Department of Transportation, academia, and industry. Irma began as a high-resolution, physics-based Infrared (IR) target and background signature model for tactical weapon applications and has grown to include: a laser (or active) channel (1990), improved scene generator to support correlated frame-to-frame imagery (1992), and passive IR/millimeter wave (MMW) channel for a co-registered active/passive IR/MMW model (1994). Irma version 5.0 was released in 2000 and encompassed several upgrades to both the physical models and software; host support was expanded to Windows, Linux, Solaris, and SGI Irix platforms. In 2005, version 5.1 was released after an extensive verification and validation of an upgraded and reengineered active channel. Since 2005, the reengineering effort has focused on the Irma passive channel. Field measurements for the validation effort include the unpolarized data collection. Irma 5.2 is scheduled for release in the summer of 2007. This paper will report the validation test results of the Irma passive models and discuss the new features in Irma 5.2.

The Induction of Chaos in Electronic Circuits Final Report-October 1, 2001

DOE Office of Scientific and Technical Information (OSTI.GOV)

R.M.Wheat, Jr.

2003-04-01

This project, now known by the name ''Chaos in Electronic Circuits,'' was originally tasked as a two-year project to examine various ''fault'' or ''non-normal'' operational states of common electronic circuits with some focus on determining the feasibility of exploiting these states. Efforts over the two-year duration of this project have been dominated by the study of the chaotic behavior of electronic circuits. These efforts have included setting up laboratory space and hardware for conducting laboratory tests and experiments, acquiring and developing computer simulation and analysis capabilities, conducting literature surveys, developing test circuitry and computer models to exercise and test ourmore » capabilities, and experimenting with and studying the use of RF injection as a means of inducing chaotic behavior in electronics. An extensive array of nonlinear time series analysis tools have been developed and integrated into a package named ''After Acquisition'' (AA), including capabilities such as Delayed Coordinate Embedding Mapping (DCEM), Time Resolved (3-D) Fourier Transform, and several other phase space re-creation methods. Many computer models have been developed for Spice and for the ATP (Alternative Transients Program), modeling the several working circuits that have been developed for use in the laboratory. And finally, methods of induction of chaos in electronic circuits have been explored.« less

Type Safe Extensible Programming

NASA Astrophysics Data System (ADS)

Chae, Wonseok

2009-10-01

Software products evolve over time. Sometimes they evolve by adding new features, and sometimes by either fixing bugs or replacing outdated implementations with new ones. When software engineers fail to anticipate such evolution during development, they will eventually be forced to re-architect or re-build from scratch. Therefore, it has been common practice to prepare for changes so that software products are extensible over their lifetimes. However, making software extensible is challenging because it is difficult to anticipate successive changes and to provide adequate abstraction mechanisms over potential changes. Such extensibility mechanisms, furthermore, should not compromise any existing functionality during extension. Software engineers would benefit from a tool that provides a way to add extensions in a reliable way. It is natural to expect programming languages to serve this role. Extensible programming is one effort to address these issues. In this thesis, we present type safe extensible programming using the MLPolyR language. MLPolyR is an ML-like functional language whose type system provides type-safe extensibility mechanisms at several levels. After presenting the language, we will show how these extensibility mechanisms can be put to good use in the context of product line engineering. Product line engineering is an emerging software engineering paradigm that aims to manage variations, which originate from successive changes in software.

AFWAL FY80 Technical Accomplishments Report.

DTIC Science & Technology

1981-12-01

through cooperative effort of the Materials and Certain compositions in the titanium aluminide Propulsion Laboratories. In addition to an extensive system...Bonded Structures Technology Transitioned .................................................. 43 Superplastically Formed and Diffusion Bonded Titanium ...Technology ................................................................................................. 75 First RSR Radial Wafer Blade Engine Test

DECISION-SUPPORT TOOLS FOR MANAGING WASTEWATER COLLECTION SYSTEMS

EPA Science Inventory

Wastewater collection systems are an extensive part of the nation's infrastructure. As these systems become older, more preventative maintenance and renewal are required. For municipalities to cost-effectively plan, organize, and implement this effort, they require improved inf...

Inquiry, Investigation, and Communication in the Student-Directed Laboratory.

ERIC Educational Resources Information Center

Janners, Martha Y.

1988-01-01

Describes how to organize a student-directed laboratory investigation which is based on amphibian metamorphosis, lasts for nearly a term, and involves extensive group effort. Explains the assignment, student response and opinion, formal paper, and instructor responsibilities. (RT)

Characterization of Stress Corrosion Cracking Using Laser Ultrasonics

DOT National Transportation Integrated Search

2008-08-31

In-service inspection of gas and oil pipelines is a subject of great current interest. Issues of safety and fitness for service have driven extensive efforts to develop effective monitoring and inspection techniques. A number of effective NDT techniq...

Design considerations for bridge deck joint-sealing systems : summary report.

DOT National Transportation Integrated Search

1992-07-01

This is a report summary which summarizes a three year research effort related to the study of bridge deck expansion joint movements. Bridge deck expansion joint systems often develop serious problems requiring extensive and expensive maintenance. Th...

Commercial Vehicle Information Exchange Window (CVIEW) Roadside Enforcement/Compliance Project

DOT National Transportation Integrated Search

2012-09-04

An extensive effort was undertaken by Clough Harbour & Associates on behalf of, and with assistance from, the New : York State Department of Transportation (NYSDOT) in order to research and design a prototype roadside commercial : vehicle electronic ...

Comparison of numerical model simulations and SFO wake vortex windline measurements

DOT National Transportation Integrated Search

2003-06-23

To provide quantitative support for the Simultaneous Offset Instrument Approach (SOIA) procedure, an extensive data collection effort was undertaken at San Francisco International Airport by the Federal Aviation Administration (FAA, U.S. Dept. of Tra...

76 FR 71066 - HUD Draft Environmental Justice Strategy, Extension of Public Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

... may access this number through TTY by calling the toll-free Federal Relay Service at (800) 877-8339... step in a larger Administration-wide effort to ensure strong protection from environmental and health...

The conception, birth, and growth of a missile umbilical system

NASA Technical Reports Server (NTRS)

Nordman, G. W.

1977-01-01

The design development was traced for the sprint 2 and improved sprint 2 missile system (ISMS) umbilical system. The unique system requirements, umbilical designs considered to meet the requirements, and the problems encountered and solutions derived during the design, and development testing of the selected systems are described. The sprint 2 development effort consisted of design, analysis, and testing activities. The ISMS effort involved the performance of an extensive trade study to determine the optimum design to meet the ISMS conditions.

Remote detection of riverine traffic using an ad hoc wireless sensor network

NASA Astrophysics Data System (ADS)

Athan, Stephan P.

2005-05-01

Trafficking of illegal drugs on riverine and inland waterways continues to proliferate in South America. While there has been a successful joint effort to cut off overland and air trafficking routes, there exists a vast river network and Amazon region consisting of over 13,000 water miles that remains difficult to adequately monitor, increasing the likelihood of narcotics moving along this extensive river system. Hence, an effort is underway to provide remote unattended riverine detection in lieu of manned or attended detection measures.

Tamara Shapiro Ledley Receives 2013 Excellence in Geophysical Education Award: Citation

NASA Astrophysics Data System (ADS)

Reiff, Patricia

2014-01-01

It gives me great pleasure to cite Tamara Shapiro Ledley for the AGU Excellence in Geophysical Education Award "for her outstanding sustained leadership in Earth systems and climate change education." Tamara has shown an ongoing commitment to bridging the scientific and educational communities to make geophysical science knowledge and data accessible and usable to teachers and students and by extension to all citizens. She works extensively with both the scientific and educational communities. She began her educational work in 1990 as the leader for weather and climate in my Teacher Research program at Rice University. She continued as the lead for atmospheric sciences in our projects Earth Today and Museums Teaching Planet Earth, which introduced her to the Earth Science Information Partners (ESIP Federation). She has served many roles at ESIP, including creating the Standing Committee for Education and serving as vice president. ESIP recognized her many accomplishments with its President's Award in 2012. At TERC her education and outreach efforts have blossomed. She was the lead author of the "Earth as a System" investigation of the GLOBE Teacher's Guide. She was a member of the original Digital Library for Earth System Education (DLESE) Data Access Working Group in 2001, where the idea for a cookbook-like resource to facilitate the use of Earth science data by teachers and students resulted in her leading the development of the "Earth Exploration Toolbook" (EET), which allows teachers to easily access and use real scientific data in the classroom. Her efforts were recognized with the EET being awarded Science Magazine's Science Prize for Online Research in Education in 2011.

Building a Biomedical Cyberinfrastructure for Collaborative Research

PubMed Central

Schad, Peter A.; Mobley, Lee Rivers; Hamilton, Carol M.

2018-01-01

For the potential power of genome-wide association studies (GWAS) and translational medicine to be realized, the biomedical research community must adopt standard measures, vocabularies, and systems to establish an extensible biomedical cyberinfrastructure. Incorporating standard measures will greatly facilitate combining and comparing studies via meta-analysis, which is a means for deriving larger populations, needed for increased statistical power to detect less apparent and more complex associations (gene-environment interactions and polygenic gene-gene interactions). Incorporating consensus-based and well-established measures into various studies should reduce the variability across studies due to attributes of measurement, making findings across studies more comparable. This article describes two consensus-based approaches to establishing standard measures and systems: PhenX (consensus measures for Phenotypes and eXposures), and the Open Geospatial Consortium (OGC). National Institutes of Health support for these efforts has produced the PhenX Toolkit, an assembled catalog of standard measures for use in GWAS and other large-scale genomic research efforts, and the RTI Spatial Impact Factor Database (SIFD), a comprehensive repository of georeferenced variables and extensive metadata that conforms to OGC standards. The need for coordinated development of cyberinfrastructure to support collaboration and data interoperability is clear, and we discuss standard protocols for ensuring data compatibility and interoperability. Adopting a cyberinfrastructure that includes standard measures, vocabularies, and open-source systems architecture will enhance the potential of future biomedical and translational research. Establishing and maintaining the cyberinfrastructure will require a fundamental change in the way researchers think about study design, collaboration, and data storage and analysis. PMID:21521587

Multidisciplinary Design Technology Development: A Comparative Investigation of Integrated Aerospace Vehicle Design Tools

NASA Technical Reports Server (NTRS)

Renaud, John E.; Batill, Stephen M.; Brockman, Jay B.

1999-01-01

This research effort is a joint program between the Departments of Aerospace and Mechanical Engineering and the Computer Science and Engineering Department at the University of Notre Dame. The purpose of the project was to develop a framework and systematic methodology to facilitate the application of Multidisciplinary Design Optimization (MDO) to a diverse class of system design problems. For all practical aerospace systems, the design of a systems is a complex sequence of events which integrates the activities of a variety of discipline "experts" and their associated "tools". The development, archiving and exchange of information between these individual experts is central to the design task and it is this information which provides the basis for these experts to make coordinated design decisions (i.e., compromises and trade-offs) - resulting in the final product design. Grant efforts focused on developing and evaluating frameworks for effective design coordination within a MDO environment. Central to these research efforts was the concept that the individual discipline "expert", using the most appropriate "tools" available and the most complete description of the system should be empowered to have the greatest impact on the design decisions and final design. This means that the overall process must be highly interactive and efficiently conducted if the resulting design is to be developed in a manner consistent with cost and time requirements. The methods developed as part of this research effort include; extensions to a sensitivity based Concurrent Subspace Optimization (CSSO) NMO algorithm; the development of a neural network response surface based CSSO-MDO algorithm; and the integration of distributed computing and process scheduling into the MDO environment. This report overviews research efforts in each of these focus. A complete bibliography of research produced with support of this grant is attached.

Insights into mammalian biology from the wild house mouse Mus musculus

PubMed Central

Phifer-Rixey, Megan; Nachman, Michael W

2015-01-01

The house mouse, Mus musculus, was established in the early 1900s as one of the first genetic model organisms owing to its short generation time, comparatively large litters, ease of husbandry, and visible phenotypic variants. For these reasons and because they are mammals, house mice are well suited to serve as models for human phenotypes and disease. House mice in the wild consist of at least three distinct subspecies and harbor extensive genetic and phenotypic variation both within and between these subspecies. Wild mice have been used to study a wide range of biological processes, including immunity, cancer, male sterility, adaptive evolution, and non-Mendelian inheritance. Despite the extensive variation that exists among wild mice, classical laboratory strains are derived from a limited set of founders and thus contain only a small subset of this variation. Continued efforts to study wild house mice and to create new inbred strains from wild populations have the potential to strengthen house mice as a model system. DOI: http://dx.doi.org/10.7554/eLife.05959.001 PMID:25875302

Autonomous Wheeled Robot Platform Testbed for Navigation and Mapping Using Low-Cost Sensors

NASA Astrophysics Data System (ADS)

Calero, D.; Fernandez, E.; Parés, M. E.

2017-11-01

This paper presents the concept of an architecture for a wheeled robot system that helps researchers in the field of geomatics to speed up their daily research on kinematic geodesy, indoor navigation and indoor positioning fields. The presented ideas corresponds to an extensible and modular hardware and software system aimed at the development of new low-cost mapping algorithms as well as at the evaluation of the performance of sensors. The concept, already implemented in the CTTC's system ARAS (Autonomous Rover for Automatic Surveying) is generic and extensible. This means that it is possible to incorporate new navigation algorithms or sensors at no maintenance cost. Only the effort related to the development tasks required to either create such algorithms needs to be taken into account. As a consequence, change poses a much small problem for research activities in this specific area. This system includes several standalone sensors that may be combined in different ways to accomplish several goals; that is, this system may be used to perform a variety of tasks, as, for instance evaluates positioning algorithms performance or mapping algorithms performance.

The NWRA Classification Infrastructure: description and extension to the Discriminant Analysis Flare Forecasting System (DAFFS)

NASA Astrophysics Data System (ADS)

Leka, K. D.; Barnes, Graham; Wagner, Eric

2018-04-01

A classification infrastructure built upon Discriminant Analysis (DA) has been developed at NorthWest Research Associates for examining the statistical differences between samples of two known populations. Originating to examine the physical differences between flare-quiet and flare-imminent solar active regions, we describe herein some details of the infrastructure including: parametrization of large datasets, schemes for handling "null" and "bad" data in multi-parameter analysis, application of non-parametric multi-dimensional DA, an extension through Bayes' theorem to probabilistic classification, and methods invoked for evaluating classifier success. The classifier infrastructure is applicable to a wide range of scientific questions in solar physics. We demonstrate its application to the question of distinguishing flare-imminent from flare-quiet solar active regions, updating results from the original publications that were based on different data and much smaller sample sizes. Finally, as a demonstration of "Research to Operations" efforts in the space-weather forecasting context, we present the Discriminant Analysis Flare Forecasting System (DAFFS), a near-real-time operationally-running solar flare forecasting tool that was developed from the research-directed infrastructure.

Policy insights from the nutritional food market transformation model: the case of obesity prevention.

PubMed

Struben, Jeroen; Chan, Derek; Dubé, Laurette

2014-12-01

This paper presents a system dynamics policy model of nutritional food market transformation, tracing over-time interactions between the nutritional quality of supply, consumer food choice, population health, and governmental policy. Applied to the Canadian context and with body mass index as the primary outcome, we examine policy portfolios for obesity prevention, including (1) industry self-regulation efforts, (2) health- and nutrition-sensitive governmental policy, and (3) efforts to foster health- and nutrition-sensitive innovation. This work provides novel theoretical and practical insights on drivers of nutritional market transformations, highlighting the importance of integrative policy portfolios to simultaneously shift food demand and supply for successful and self-sustaining nutrition and health sensitivity. We discuss model extensions for deeper and more comprehensive linkages of nutritional food market transformation with supply, demand, and policy in agrifood and health/health care. These aim toward system design and policy that can proactively, and with greater impact, scale, and resilience, address single as well as double malnutrition in varying country settings. © 2014 New York Academy of Sciences.

The AlpArray Seismic Network: current status and next steps

NASA Astrophysics Data System (ADS)

Hetényi, György; Molinari, Irene; Clinton, John; Kissling, Edi

2016-04-01

The AlpArray initiative (http://www.alparray.ethz.ch) is a large-scale European collaboration to study the entire Alpine orogen at high resolution and in 3D with a large variety of geoscientific methods. The core element of the initiative is an extensive and dense broadband seismological network, the AlpArray Seismic Network (AASN), which complements the permanent seismological stations to ensure homogeneous coverage of the greater Alpine area. The some 260 temporary stations of the AlpArray Seismic Network are operated as a joint effort by a number of institutions from Austria, Bosnia-Herzegovina, Croatia, Czech Republic, France, Germany, Hungary, Italy, Slovakia and Switzerland. The first stations were installed in Spring 2015 and the full AASN is planned to be operational by early Summer 2016. In this poster we present the actual status of the deployment, the effort undertaken by the contributing groups, station performance, typical noise levels, best practices in installation as well as in data management, often encountered challenges, and planned next steps including the deployment of ocean bottom seismometers in the Ligurian Sea.

Stress Analysis and Testing at the Marshall Space Flight Center to Study Cause and Corrective Action of Space Shuttle External Tank Stringer Failures

NASA Technical Reports Server (NTRS)

Wingate, Robert J.

2012-01-01

After the launch scrub of Space Shuttle mission STS-133 on November 5, 2010, large cracks were discovered in two of the External Tank intertank stringers. The NASA Marshall Space Flight Center, as managing center for the External Tank Project, coordinated the ensuing failure investigation and repair activities with several organizations, including the manufacturer, Lockheed Martin. To support the investigation, the Marshall Space Flight Center formed an ad-hoc stress analysis team to complement the efforts of Lockheed Martin. The team undertook six major efforts to analyze or test the structural behavior of the stringers. Extensive finite element modeling was performed to characterize the local stresses in the stringers near the region of failure. Data from a full-scale tanking test and from several subcomponent static load tests were used to confirm the analytical conclusions. The analysis and test activities of the team are summarized. The root cause of the stringer failures and the flight readiness rationale for the repairs that were implemented are discussed.

Life Modeling and Design Analysis for Ceramic Matrix Composite Materials

NASA Technical Reports Server (NTRS)

2005-01-01

The primary research efforts focused on characterizing and modeling static failure, environmental durability, and creep-rupture behavior of two classes of ceramic matrix composites (CMC), silicon carbide fibers in a silicon carbide matrix (SiC/SiC) and carbon fibers in a silicon carbide matrix (C/SiC). An engineering life prediction model (Probabilistic Residual Strength model) has been developed specifically for CMCs. The model uses residual strength as the damage metric for evaluating remaining life and is posed probabilistically in order to account for the stochastic nature of the material s response. In support of the modeling effort, extensive testing of C/SiC in partial pressures of oxygen has been performed. This includes creep testing, tensile testing, half life and residual tensile strength testing. C/SiC is proposed for airframe and propulsion applications in advanced reusable launch vehicles. Figures 1 and 2 illustrate the models predictive capabilities as well as the manner in which experimental tests are being selected in such a manner as to ensure sufficient data is available to aid in model validation.

NASA developments in solid state power amplifiers

NASA Technical Reports Server (NTRS)

Leonard, Regis F.

1990-01-01

Over the last ten years, NASA has undertaken an extensive program aimed at development of solid state power amplifiers for space applications. Historically, the program may be divided into three phases. The first efforts were carried out in support of the advanced communications technology satellite (ACTS) program, which is developing an experimental version of a Ka-band commercial communications system. These first amplifiers attempted to use hybrid technology. The second phase was still targeted at ACTS frequencies, but concentrated on monolithic implementations, while the current, third phase, is a monolithic effort that focusses on frequencies appropriate for other NASA programs and stresses amplifier efficiency. The topics covered include: (1) 20 GHz hybrid amplifiers; (2) 20 GHz monolithic MESFET power amplifiers; (3) Texas Instruments' (TI) 20 GHz variable power amplifier; (4) TI 20 GHz high power amplifier; (5) high efficiency monolithic power amplifiers; (6) GHz high efficiency variable power amplifier; (7) TI 32 GHz monolithic power amplifier performance; (8) design goals for Hughes' 32 GHz variable power amplifier; and (9) performance goals for Hughes' pseudomorphic 60 GHz power amplifier.

Fatigue life prediction modeling for turbine hot section materials

NASA Technical Reports Server (NTRS)

Halford, G. R.; Meyer, T. G.; Nelson, R. S.; Nissley, D. M.; Swanson, G. A.

1989-01-01

A major objective of the fatigue and fracture efforts under the NASA Hot Section Technology (HOST) program was to significantly improve the analytic life prediction tools used by the aeronautical gas turbine engine industry. This was achieved in the areas of high-temperature thermal and mechanical fatigue of bare and coated high-temperature superalloys. The cyclic crack initiation and propagation resistance of nominally isotropic polycrystalline and highly anisotropic single crystal alloys were addressed. Life prediction modeling efforts were devoted to creep-fatigue interaction, oxidation, coatings interactions, multiaxiality of stress-strain states, mean stress effects, cumulative damage, and thermomechanical fatigue. The fatigue crack initiation life models developed to date include the Cyclic Damage Accumulation (CDA) and the Total Strain Version of Strainrange Partitioning (TS-SRP) for nominally isotropic materials, and the Tensile Hysteretic Energy Model for anisotropic superalloys. A fatigue model is being developed based upon the concepts of Path-Independent Integrals (PII) for describing cyclic crack growth under complex nonlinear response at the crack tip due to thermomechanical loading conditions. A micromechanistic oxidation crack extension model was derived. The models are described and discussed.

Synthesis of User Needs for Arctic Sea Ice Predictions

NASA Astrophysics Data System (ADS)

Wiggins, H. V.; Turner-Bogren, E. J.; Sheffield Guy, L.

2017-12-01

Forecasting Arctic sea ice on sub-seasonal to seasonal scales in a changing Arctic is of interest to a diverse range of stakeholders. However, sea ice forecasting is still challenging due to high variability in weather and ocean conditions and limits to prediction capabilities; the science needs for observations and modeling are extensive. At a time of challenged science funding, one way to prioritize sea ice prediction efforts is to examine the information needs of various stakeholder groups. This poster will present a summary and synthesis of existing surveys, reports, and other literature that examines user needs for sea ice predictions. The synthesis will include lessons learned from the Sea Ice Prediction Network (a collaborative, multi-agency-funded project focused on seasonal Arctic sea ice predictions), the Sea Ice for Walrus Outlook (a resource for Alaska Native subsistence hunters and coastal communities, that provides reports on weather and sea ice conditions), and other efforts. The poster will specifically compare the scales and variables of sea ice forecasts currently available, as compared to what information is requested by various user groups.

Fatigue life prediction modeling for turbine hot section materials

NASA Technical Reports Server (NTRS)

Halford, G. R.; Meyer, T. G.; Nelson, R. S.; Nissley, D. M.; Swanson, G. A.

1988-01-01

A major objective of the fatigue and fracture efforts under the Hot Section Technology (HOST) program was to significantly improve the analytic life prediction tools used by the aeronautical gas turbine engine industry. This was achieved in the areas of high-temperature thermal and mechanical fatigue of bare and coated high-temperature superalloys. The cyclic crack initiation and propagation resistance of nominally isotropic polycrystalline and highly anisotropic single crystal alloys were addressed. Life prediction modeling efforts were devoted to creep-fatigue interaction, oxidation, coatings interactions, multiaxiality of stress-strain states, mean stress effects, cumulative damage, and thermomechanical fatigue. The fatigue crack initiation life models developed to date include the Cyclic Damage Accumulation (CDA) and the Total Strain Version of Strainrange Partitioning (TS-SRP) for nominally isotropic materials, and the Tensile Hysteretic Energy Model for anisotropic superalloys. A fatigue model is being developed based upon the concepts of Path-Independent Integrals (PII) for describing cyclic crack growth under complex nonlinear response at the crack tip due to thermomechanical loading conditions. A micromechanistic oxidation crack extension model was derived. The models are described and discussed.

Guidelines for development of the Iowa statewide transportation improvement program (STIP). Revised.

DOT National Transportation Integrated Search

2004-01-01

The Transportation Equity Act for the 21st Century (TEA-21) continues the Intermodal Surface Transportation Efficiency Act of 1991's requirement for an extensive, ongoing cooperative planning effort for programming federal funding. Iowa's STIP is dev...

THE NEUROTOXICANT TRIMETHYLTIN STIMULATES APOPTOSIS VIA OXIDATIVE STRESS, CASPASE ACTIVATION AND P38 PROTEIN KINASE.

EPA Science Inventory

Acute exposure to the tri-substituted organotin trimethyltin (TMT) causes neuronal degeneration in the hippocampus, amygdala, pyriform cortex, and neocortex. Developmental exposure to TMT impairs later learning and memory. Despite extensive efforts elucidating neuropathological...

Mulptiple Sclerosis, Symptoms, Diagnosis, Treatment and Latest NIH Research | NIH MedlinePlus the Magazine

MedlinePlus

... Multiple Sclerosis: Symptoms, Diagnosis, Treatment and Latest NIH Research Past Issues / Spring 2012 Table of Contents Symptoms ... my MS will ever go away? Latest NIH Research Scientists continue their extensive efforts to create new ...

TIMSS 2007 Assessment Frameworks

ERIC Educational Resources Information Center

Mullis, Ina V. S.; Martin, Michael O.; Ruddock, Graham J.; O'Sullivan, Christine Y.; Arora, Alka; Erberber, Ebru

2005-01-01

Developing the Trends in International Mathematics and Science Study (TIMSS) 2007 Assessment Frameworks represents an extensive collaborative effort involving individuals and expert groups from more than 60 countries around the world. The document contains three frameworks for implementing TIMSS 2007--the Mathematics Framework, the Science…

Curating and sharing structures and spectra for the environmental community

EPA Science Inventory

The increasing popularity of high mass accuracy non-target mass spectrometry methods has yielded extensive identification efforts based on spectral and chemical compound databases in the environmental community and beyond. Increasingly, new methods are relying on open data resour...

77 FR 11625 - Child Restraint Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-27

...),'' Stammen; Vehicle Research and Test Center, National Highway Traffic Safety Administration (September 2004... exceeded. However, during extensive post-NPRM booster seat testing, inconsistencies in the test protocol... substantial rulemaking and research efforts to try to address test variability. NHTSA investigated the ATD's...

ASAS Centennial Paper: Future needs of research and extension in forage utilization.

PubMed

Rouquette, F M; Redmon, L A; Aiken, G E; Hill, G M; Sollenberger, L E; Andrae, J

2009-01-01

Forage-animal production agriculture is implementing infrastructure changes and management strategies to adjust to increased energy-related costs of fuel, feed grains, fertilizers, and seeds. The primary objectives of this position paper are to assess future research and extension scientific needs in forage utilization, financial support for the discipline, and changing status and number of scientists. A survey questionnaire returned from 25 land-grant universities in the eastern half of the United States rated the top 4 research needs as 1) pasture systems and efficiency of production; 2) interfacing with energy concerns; 3) forage cultivar evaluations and persistence; and 4) environment impacts. Plant-animal future research needs at 11 USDA-ARS regional locations are targeted at sustainable management and improved livestock performance, ecophysiology and ecology of grasslands, environment impacts, and improved technologies for nutritive value assessments. Extension scientists from 17 southern and northeastern states listed the top 3 needs as forage persistence, soil fertility and nutrient management, and pasture systems and efficiency of production. Grant funds currently provide more than 40% of land-grant university research and extension efforts in forage utilization, and scientists estimate that this support base will increase to 55 to 60% of the funding total by 2013. Reduced allocation of state and federal funding has contributed to a reduction in the number of full-time equivalent (FTE) scientists engaged in forage utilization research and extension activities. The current 25 state FTE conducting research number about 2.8 per state. This includes 10 states with >3, 11 states with <2, and 3 states with <1 FTE. Increased interest in cellulosic energy, climate change, and environmental impact may offer new opportunities for these FTE to participate in integrated cross-discipline research Extension programming, and technology transfer methods will change to accommodate reduced funding but with increasing numbers of novice, recreation-oriented landowners.

Glucose control and use of continuous glucose monitoring in the intensive care unit: a critical review.

PubMed

De Block, Christophe; Manuel-y-Keenoy, Begoña; Rogiers, Peter; Jorens, Philippe; Van Gaal, Luc

2008-08-01

Stress hyperglycemia recently became a major therapeutic target in the Intensive Care Unit (ICU) since it occurs in most critically ill patients and is associated with adverse outcome, including increased mortality. Intensive insulin therapy to achieve normoglycemia may reduce mortality, morbidity and the length of ICU and in-hospital stay. However, obtaining normoglycemia requires extensive efforts from the medical staff, including frequent glucose monitoring and adjustment of insulin dose. Current insulin titration is based upon discrete glucose measurements, which may miss fast changes in glycemia and which does not give a full picture of overall glycemic control. Recent evidence suggests that continuous monitoring of glucose levels may help to signal glycemic excursions and eventually to optimize insulin titration in the ICU. In this review we will summarise monitoring and treatment strategies to achieve normoglycemia in the ICU, with special emphasis on the possible advantages of continuous glucose monitoring.

The role of hinges in primary total knee replacement.

PubMed

Gehrke, T; Kendoff, D; Haasper, C

2014-11-01

The use of hinged implants in primary total knee replacement (TKR) should be restricted to selected indications and mainly for elderly patients. Potential indications for a rotating hinge or pure hinge implant in primary TKR include: collateral ligament insufficiency, severe varus or valgus deformity (>20°) with necessary relevant soft-tissue release, relevant bone loss including insertions of collateral ligaments, gross flexion-extension gap imbalance, ankylosis, or hyperlaxity. Although data reported in the literature are inconsistent, clinical results depend on implant design, proper technical use, and adequate indications. We present our experience with a specific implant type that we have used for over 30 years and which has given our elderly patients good mid-term results. Because revision of implants with long cemented stems can be very challenging, an effort should be made in the future to use shorter stems in modular versions of hinged implants. ©2014 The British Editorial Society of Bone & Joint Surgery.

Arctic National Wildlife Refuge, Alaska, Coastal Plain Resource Assessment: Report and recommendation to the Congress of the United States and final legislative environmental impact statement

USGS Publications Warehouse

,

1987-01-01

The Arctic National Wildlife Refuge, in the northeastern corner of Alaska, was first established as the Arctic National Wildlife Range by Public Land Order 2214 in 1960, for the purpose of preserving unique wildlife, wilderness, and recreational values. The original 8.9-millionacre Range was withdrawn from all forms of appropriation under the public land laws, including mining laws but not including mineral leasing laws. This order culminated extensive efforts begun more than a decade earlier to preserve this unique part of Alaska. The following report analyzes the potential environmental consequences of five management alternatives for the coastal plain, ranging from opening for lease of the entire area for oil and gas development, to wilderness designation. A legislative environmental impact statement has been integrated into the report.

Semantic Support for Complex Ecosystem Research Environments

NASA Astrophysics Data System (ADS)

Klawonn, M.; McGuinness, D. L.; Pinheiro, P.; Santos, H. O.; Chastain, K.

2015-12-01

As ecosystems come under increasing stresses from diverse sources, there is growing interest in research efforts aimed at monitoring, modeling, and improving understanding of ecosystems and protection options. We aimed to provide a semantic infrastructure capable of representing data initially related to one large aquatic ecosystem research effort - the Jefferson project at Lake George. This effort includes significant historical observational data, extensive sensor-based monitoring data, experimental data, as well as model and simulation data covering topics including lake circulation, watershed runoff, lake biome food webs, etc. The initial measurement representation has been centered on monitoring data and related provenance. We developed a human-aware sensor network ontology (HASNetO) that leverages existing ontologies (PROV-O, OBOE, VSTO*) in support of measurement annotations. We explicitly support the human-aware aspects of human sensor deployment and collection activity to help capture key provenance that often is lacking. Our foundational ontology has since been generalized into a family of ontologies and used to create our human-aware data collection infrastructure that now supports the integration of measurement data along with simulation data. Interestingly, we have also utilized the same infrastructure to work with partners who have some more specific needs for specifying the environmental conditions where measurements occur, for example, knowing that an air temperature is not an external air temperature, but of the air temperature when windows are shut and curtains are open. We have also leveraged the same infrastructure to work with partners more interested in modeling smart cities with data feeds more related to people, mobility, environment, and living. We will introduce our human-aware data collection infrastructure, and demonstrate how it uses HASNetO and its supporting SOLR-based search platform to support data integration and semantic browsing. Further we will present learnings from its use in three relatively diverse large ecosystem research efforts and highlight some benefits and challenges related to our semantically-enhanced foundation.

Nuclear physics research at the University of Richmond. Progress report, November 1, 1994--October 31, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vineyard, M.F.; Gilfoyle, G.P.; Major, R.W.

Summarized in this report is the progress achieved during the period from November 1, 1994 to October 31, 1995. The experimental work described in this report is in electromagnetic and heavy-ion nuclear physics. The effort in electromagnetic nuclear physics is in preparation for the research program at the Continuous Electron Beam Accelerator Facility (CEBAF) and is focused on the construction and use of the CEBAF Large Acceptance Spectrometer (CLAS). The heavy-ion experiments were performed at the Argonne National Laboratory ATLAS facility and SUNY, Stony Brook. The physics interests driving these efforts at CEBAF are in the study of the structure,more » interactions, and nuclear-medium modifications of mesons and baryons. This year, an extension of the experiment to measure the magnetic form factor of the neutron was approved by the CEBAF Program Advisory Committee Nine (PAC9) for beam at 6 GeV. The authors also submitted updates to PAC9 on the experiments to measure inclusive {eta} photoproduction in nuclei and electroproduction of the {Lambda}, {Lambda}*(1520), and f{sub 0}(975). In addition to these experiments, the authors collaborated on a proposal to measure rare radiative decays of the {phi} meson which was also approved by PAC9. Their contributions to the construction of the CLAS include the development of the drift-chamber gas system, drift-chamber software, and controls software. Major has been leading the effort in the construction of the gas system. In the last year, the Hall B gas shed was constructed and the installation of the gas system components built at the University of Richmond has begun. Over the last six years, the efforts in low-energy heavy-ion physics have decreased due to the change in focus to electromagnetic nuclear physics at CEBAF. Most of the heavy-ion work is completed and there are now new experiments planned. Included in this report are two papers resulting from collaborations on heavy-ion experiments.« less

Challenges and Rewards on the Road to Translational Systems Biology in Acute Illness: Four Case Reports from Interdisciplinary Teams

PubMed Central

An, Gary; Hunt, C. Anthony; Clermont, Gilles; Neugebauer, Edmund; Vodovotz, Yoram

2007-01-01

Introduction Translational systems biology approaches can be distinguished from mainstream systems biology in that their goal is to drive novel therapies and streamline clinical trials in critical illness. One systems biology approach, dynamic mathematical modeling (DMM), is increasingly used in dealing with the complexity of the inflammatory response and organ dysfunction. The use of DMM often requires a broadening of research methods and a multidisciplinary team approach that includes bioscientists, mathematicians, engineers, and computer scientists. However, the development of these groups must overcome domain-specific barriers to communication and understanding. Methods We present four case studies of successful translational, interdisciplinary systems biology efforts, which differ by organizational level from an individual to an entire research community. Results Case 1 is a single investigator involved in DMM of the acute inflammatory response at Cook County Hospital, in which extensive translational progress was made using agent-based models of inflammation and organ damage. Case 2 is a community-level effort from the University of Witten-Herdecke in Cologne, whose efforts have led to the formation of the Society for Complexity in Acute Illness. Case 3 is an institution-based group, the Biosystems Group at the University of California, San Francisco, whose work has included a focus on a common lexicon for DMM. Case 4 is an institution-based, trans-disciplinary research group (the Center for Inflammation and Regenerative Modeling at the University of Pittsburgh, whose modeling work has led to internal education efforts, grant support, and commercialization. Conclusion A transdisciplinary approach, which involves team interaction in an iterative fashion to address ambiguity and is supported by educational initiatives, is likely to be necessary for DMM in acute illness. Community-wide organizations such as the Society of Complexity in Acute Illness (SCAI) must strive to facilitate the implementation of DMM in sepsis/trauma research into the research community as a whole. PMID:17548029

Pika: A snow science simulation tool built using the open-source framework MOOSE

NASA Astrophysics Data System (ADS)

Slaughter, A.; Johnson, M.

2017-12-01

The Department of Energy (DOE) is currently investing millions of dollars annually into various modeling and simulation tools for all aspects of nuclear energy. An important part of this effort includes developing applications based on the open-source Multiphysics Object Oriented Simulation Environment (MOOSE; mooseframework.org) from Idaho National Laboratory (INL).Thanks to the efforts of the DOE and outside collaborators, MOOSE currently contains a large set of physics modules, including phase-field, level set, heat conduction, tensor mechanics, Navier-Stokes, fracture and crack propagation (via the extended finite-element method), flow in porous media, and others. The heat conduction, tensor mechanics, and phase-field modules, in particular, are well-suited for snow science problems. Pika--an open-source MOOSE-based application--is capable of simulating both 3D, coupled nonlinear continuum heat transfer and large-deformation mechanics applications (such as settlement) and phase-field based micro-structure applications. Additionally, these types of problems may be coupled tightly in a single solve or across length and time scales using a loosely coupled Picard iteration approach. In addition to the wide range of physics capabilities, MOOSE-based applications also inherit an extensible testing framework, graphical user interface, and documentation system; tools that allow MOOSE and other applications to adhere to nuclear software quality standards. The snow science community can learn from the nuclear industry and harness the existing effort to build simulation tools that are open, modular, and share a common framework. In particular, MOOSE-based multiphysics solvers are inherently parallel, dimension agnostic, adaptive in time and space, fully coupled, and capable of interacting with other applications. The snow science community should build on existing tools to enable collaboration between researchers and practitioners throughout the world, and advance the state-of-the-art in line with other scientific research efforts.

MANUAL: BIOVENTING PRINCIPLES AND PRACTICE VOLUME II. BIOVENTING DESIGN

EPA Science Inventory

The results from bioventing research and development efforts and from the pilot-scale bioventing systems have been used to produce this two-volume manual. Although this design manual has been written based on extensive experience with petroleum hydrocarbons (and thus, many exampl...

Regional Sustainability: The San Luis Basin Metrics Project

EPA Science Inventory

There are a number of established, scientifically supported metrics of sustainability. Many of the metrics are data intensive and require extensive effort to collect data and compute. Moreover, individual metrics may not capture all aspects of a system that are relevant to sust...

The Valley without Birds.

ERIC Educational Resources Information Center

Breslin, Patrick

1988-01-01

Describes cooperative campaign by central Chilean farmers to reduce use of dangerous chemicals. Describes cooperative's rural extension program targeting misuse of pesticides. Describes concern of chemical danger to local and foreign consumers. Cooperative's effort described as balancing short-term economic gains with long-term health and…

Masters Program at Claremont and Other University Extension Activities

ERIC Educational Resources Information Center

Carroll, Ann-Marie, Ed.

1971-01-01

Descriptions of a liberal studies program at Claremont College, California; the University of British Columbia local government project; recent Syracuse University publications in continuing education; Kansas State University teleteaching efforts; the interinstitutional University without Walls" consortium; and the University of Washington…

Development of a Multidisciplinary Approach to Access Sustainability

EPA Science Inventory

There are a number of established, scientifically supported metrics of sustainability. Many of the metrics are data intensive and require extensive effort to collect data and compute the metrics. Moreover, individual metrics do not capture all aspects of a system that are relevan...

Social Network Structures among Groundnut Farmers

ERIC Educational Resources Information Center

Thuo, Mary; Bell, Alexandra A.; Bravo-Ureta, Boris E.; Okello, David K.; Okoko, Evelyn Nasambu; Kidula, Nelson L.; Deom, C. Michael; Puppala, Naveen

2013-01-01

Purpose: Groundnut farmers in East Africa have experienced declines in production despite research and extension efforts to increase productivity. This study examined how social network structures related to acquisition of information about new seed varieties and productivity among groundnut farmers in Uganda and Kenya.…

Negotiating Diversity: Fostering Collaborative Interpretations of Case Studies

ERIC Educational Resources Information Center

Guo, Shujie; Cockburn-Wootten, Cheryl; Munshi, Debashish

2014-01-01

The intercultural divides in values, perceptions, and interpretations of concepts have been studied extensively by international business and intercultural communication scholars. Consequentially, much effort in university classrooms is spent on focusing on the differences between groups and on finding ways to "manage" cultural…

Routing Protocols in Wireless Sensor Networks

PubMed Central

Villalba, Luis Javier García; Orozco, Ana Lucila Sandoval; Cabrera, Alicia Triviño; Abbas, Cláudia Jacy Barenco

2009-01-01

The applications of wireless sensor networks comprise a wide variety of scenarios. In most of them, the network is composed of a significant number of nodes deployed in an extensive area in which not all nodes are directly connected. Then, the data exchange is supported by multihop communications. Routing protocols are in charge of discovering and maintaining the routes in the network. However, the appropriateness of a particular routing protocol mainly depends on the capabilities of the nodes and on the application requirements. This paper presents a review of the main routing protocols proposed for wireless sensor networks. Additionally, the paper includes the efforts carried out by Spanish universities on developing optimization techniques in the area of routing protocols for wireless sensor networks. PMID:22291515

BESTIA - the next generation ultra-fast CO 2 laser for advanced accelerator research

DOE PAGES

Pogorelsky, Igor V.; Babzien, Markus; Ben-Zvi, Ilan; ...

2015-12-02

Over the last two decades, BNL’s ATF has pioneered the use of high-peak power CO 2 lasers for research in advanced accelerators and radiation sources. In addition, our recent developments in ion acceleration, Compton scattering, and IFELs have further underscored the benefits from expanding the landscape of strong-field laser interactions deeper into the mid-infrared (MIR) range of wavelengths. This extension validates our ongoing efforts in advancing CO 2 laser technology, which we report here. Our next-generation, multi-terawatt, femtosecond CO 2 laser will open new opportunities for studying ultra-relativistic laser interactions with plasma in the MIR spectral domain, including new regimesmore » in the particle acceleration of ions and electrons.« less

Advanced Power System Analysis Capabilities

NASA Technical Reports Server (NTRS)

1997-01-01

As a continuing effort to assist in the design and characterization of space power systems, the NASA Lewis Research Center's Power and Propulsion Office developed a powerful computerized analysis tool called System Power Analysis for Capability Evaluation (SPACE). This year, SPACE was used extensively in analyzing detailed operational timelines for the International Space Station (ISS) program. SPACE was developed to analyze the performance of space-based photovoltaic power systems such as that being developed for the ISS. It is a highly integrated tool that combines numerous factors in a single analysis, providing a comprehensive assessment of the power system's capability. Factors particularly critical to the ISS include the orientation of the solar arrays toward the Sun and the shadowing of the arrays by other portions of the station.

Diode-pumped UV refractive surgery laser

NASA Astrophysics Data System (ADS)

Lin, Jui T.; Hwang, Ming-Yi; Huang, C. H.

1993-07-01

Ophthalmic applications of medical lasers have been extensively explored recently because of their market potential. Refractive surgical lasers represent one of the major development efforts due to the large population of eye disorders: about 160 million people in the USA and more than 2 billion worldwide. The first refractive laser developed was the ArF excimer laser at 193 nm in 1987 - 88 for a procedure called photorefractive keratectomy (PRK). More recently, solid state refractive lasers have also been explored for preliminary clinical trials. These lasers include Nd:YLF (picosecond at 1054 nm), doubled-Nd:YAG (nanosecond at 532 nm), Ho:YAG (microsecond at 2100 nm) and ultraviolet (UV) lasers generated from the harmonic of Ti:sapphire-laser (205 - 220 nm) and Nd:YAG (at 213 nm).

Advances in Composites Technology

NASA Technical Reports Server (NTRS)

Tenney, D. R.; Dexter, H. B.

1985-01-01

A significant level of research is currently focused on the development of tough resins and high strain fibers in an effort to gain improved damage tolerance. Moderate success has been achieved with the development of new resins such as PEEK and additional improvements look promising with new thermoplastic resins. Development of innovative material forms such as 2-D and 3-D woven fabrics and braided structural subelements is also expected to improve damage tolerance and durability of composite hardware. The new thrust in composites is to develop low cost manufacturing and design concepts to lower the cost of composite hardware. Processes being examined include automated material placement, filament winding, pultrusion, and thermoforming. The factory of the future will likely incorporate extensive automation in all aspects of manufacturing composite components.

Investigation of the nutrition problems of Central America and Panama.

PubMed

Arroyave, Guillermo

2010-03-01

From its earliest years, INCAP gave a high priority to a multidisciplinary effort to learn as much as possible about the dietary habits, nutritional status, and their consequences in the populations of Central America and Panama. Most of the papers in this Special Issue contain some of this information. The first studies were in schoolchildren but were soon extended to preschool children, pregnant and lactating women, and other adults. This paper describes the principal findings of the initial dietary, biochemical, and clinical community-based studies. From 1965-67, very extensive studies were carried out in all six countries including dietary, biochemical, clinical, and anthological studies were carried out in all six countries, the results of which are summarized.

Development of an hp-version finite element method for computational optimal control

NASA Technical Reports Server (NTRS)

Hodges, Dewey H.; Warner, Michael S.

1993-01-01

The purpose of this research effort is to develop a means to use, and to ultimately implement, hp-version finite elements in the numerical solution of optimal control problems. The hybrid MACSYMA/FORTRAN code GENCODE was developed which utilized h-version finite elements to successfully approximate solutions to a wide class of optimal control problems. In that code the means for improvement of the solution was the refinement of the time-discretization mesh. With the extension to hp-version finite elements, the degrees of freedom include both nodal values and extra interior values associated with the unknown states, co-states, and controls, the number of which depends on the order of the shape functions in each element.

Routing protocols in wireless sensor networks.

PubMed

Villalba, Luis Javier García; Orozco, Ana Lucila Sandoval; Cabrera, Alicia Triviño; Abbas, Cláudia Jacy Barenco

2009-01-01

The applications of wireless sensor networks comprise a wide variety of scenarios. In most of them, the network is composed of a significant number of nodes deployed in an extensive area in which not all nodes are directly connected. Then, the data exchange is supported by multihop communications. Routing protocols are in charge of discovering and maintaining the routes in the network. However, the appropriateness of a particular routing protocol mainly depends on the capabilities of the nodes and on the application requirements. This paper presents a review of the main routing protocols proposed for wireless sensor networks. Additionally, the paper includes the efforts carried out by Spanish universities on developing optimization techniques in the area of routing protocols for wireless sensor networks.

Ada (trademark) projects at NASA. Runtime environment issues and recommendations

NASA Technical Reports Server (NTRS)

Roy, Daniel M.; Wilke, Randall W.

1988-01-01

Ada practitioners should use this document to discuss and establish common short term requirements for Ada runtime environments. The major current Ada runtime environment issues are identified through the analysis of some of the Ada efforts at NASA and other research centers. The runtime environment characteristics of major compilers are compared while alternate runtime implementations are reviewed. Modifications and extensions to the Ada Language Reference Manual to address some of these runtime issues are proposed. Three classes of projects focusing on the most critical runtime features of Ada are recommended, including a range of immediately feasible full scale Ada development projects. Also, a list of runtime features and procurement issues is proposed for consideration by the vendors, contractors and the government.

[Nanoscale drug carriers for traditional Chinese medicine research and development].

PubMed

Yi, Cheng-xue; Yu, Jiang-nan; Xu, Xi-ming

2008-08-01

Nanocarriers generally made of natural or artificial polymers ranging in size from about 10-1 000 nm, possess versatile properties suitable for drug delivery, including good biocompatibility and biodegradability, potential capability of targeted delivery and controlled release of incorporated drugs, and have been extensively used in the development of new drug delivery systems (DDS). These types of nano-DDS have considerable potential to traditional Chinese medicine (TCM), and recently have attracted increasing efforts on the TCM research and development. In this review, the recently published literature worldwide is covered to describe the latest advances in the applications as TCM delivery carriers, and to highlight the characteristics and preparation methods of some selected examples of promising nanocarriers such as nanoparticles, lipid nanoparticles, nanoemulsions, nanomicelles and nanoliposomes.

Commercial and PET radioisotope manufacturing with a medical cyclotron

NASA Astrophysics Data System (ADS)

Boothe, T. E.; McLeod, T. F.; Plitnikas, M.; Kinney, D.; Tavano, E.; Feijoo, Y.; Smith, P.; Szelecsényi, F.

1993-06-01

Mount Sinai has extensive experience in producing radionuclides for commercial sales and for incorporation into radiopharmaceuticals, including PET. Currently, an attempt is being made to supply radiochemicals to radiopharmaceutical manufacturers outside the hospital, to prepare radiopharmaceuticals for in-house use, and to prepare PET radiopharmaceuticals, such as 2-[F-18] FDG, for outside sales. This use for both commercial and PET manufacturing is atypical for a hospital-based cyclotron. To accomplish PET radiopharmaceutical sales, the hospital operates a nuclear pharmacy. A review of operational details for the past several years shows a continuing dependence on commercial sales which is reflected in research and developmental aspects and in staffing. Developmental efforts have centered primarily on radionuclide production, target development, and radiochemical processing optimization.

Empowering America's Communities to Prepare for the Effects of Climate Change: Developing Actionable Climate Science Under the President's Climate Action Plan

NASA Astrophysics Data System (ADS)

Duffy, P. B.; Colohan, P.; Driggers, R.; Herring, D.; Laurier, F.; Petes, L.; Ruffo, S.; Tilmes, C.; Venkataraman, B.; Weaver, C. P.

2014-12-01

Effective adaptation to impacts of climate change requires best-available information. To be most useful, this information should be easily found, well-documented, and translated into tools that decision-makers use and trust. To meet these needs, the President's Climate Action Plan includes efforts to develop "actionable climate science". The Climate Data Initiative (CDI) leverages the Federal Government's extensive, open data resources to stimulate innovation and private-sector entrepreneurship in support of actions to prepare for climate change. The Initiative forges commitments and partnerships from the private, NGO, academic, and public sectors to create data-driven tools. Open data from Federal agencies to support this innovation is available on Climate.Data.gov, initially focusing on coastal flooding but soon to expand to topics including food, energy, water, energy, transportation, and health. The Climate Resilience Toolkit (CRT) will facilitate access to data-driven resilience tools, services, and best practices, including those accessible through the CDI. The CRT will also include access to training and tutorials, case studies, engagement forums, and other information sources. The Climate Action Plan also calls for a public-private partnership on extreme weather risk, with the goal of generating improved assessments of risk from different types of extreme weather events, using methods and data that are transparent and accessible. Finally, the U.S. Global Change Research Program and associated agencies work to advance the science necessary to inform decisions and sustain assessments. Collectively, these efforts represent increased emphasis across the Federal Government on the importance of information to support climate resilience.

Clinical implications from daily physiotherapy examination of 131 acute hamstring injuries and their association with running speed and rehabilitation progression.

PubMed

Whiteley, Rod; van Dyk, Nicol; Wangensteen, Arnlaug; Hansen, Clint

2018-03-01

To investigate the association of daily clinical measures and the progression of rehabilitation and perceived running effort. A cohort of 131 athletes with an MRI-confirmed acute hamstring injury underwent a standardised criteria-based rehabilitation protocol. Descriptive and inferential statistics were used to investigate the association between daily clinical subjective and objective measures and both the progression of rehabilitation and perceived running effort. These measures included different strength, palpation, flexibility and functional tests. Inter-rater and intrarater reliability and minimal detectable change were established for the clinical measures of strength and flexibility by examining measures taken on consecutive days for the uninjured leg. The progression of the daily measures was seen to be non-linear and varied according to the measure. Intra-rater reliability for the strength and flexibility measures were excellent (95% CI ≥0.85 for all measures). Strength (in the outer range position) and flexibility (in maximum hip flexion with active knee extension (MHFAKE) in supine) were best associated with rehabilitation progression and perceived running effort. Additionally, length of pain on palpation was usefully associated with rehabilitation progression. At lower perceived running effort there was a large variation in actual running speed. Daily physical measures of palpation pain, outer range strength, MHFAKE and reported pain during daily activity are useful to inform the progression of rehabilitation. NCT01812564 and NCT02104258. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Vision for an Open, Global Greenhouse Gas Information System (GHGIS)

NASA Astrophysics Data System (ADS)

Duren, R. M.; Butler, J. H.; Rotman, D.; Ciais, P.; Greenhouse Gas Information System Team

2010-12-01

Over the next few years, an increasing number of entities ranging from international, national, and regional governments, to businesses and private land-owners, are likely to become more involved in efforts to limit atmospheric concentrations of greenhouse gases. In such a world, geospatially resolved information about the location, amount, and rate of greenhouse gas (GHG) emissions will be needed, as well as the stocks and flows of all forms of carbon through the earth system. The ability to implement policies that limit GHG concentrations would be enhanced by a global, open, and transparent greenhouse gas information system (GHGIS). An operational and scientifically robust GHGIS would combine ground-based and space-based observations, carbon-cycle modeling, GHG inventories, synthesis analysis, and an extensive data integration and distribution system, to provide information about anthropogenic and natural sources, sinks, and fluxes of greenhouse gases at temporal and spatial scales relevant to decision making. The GHGIS effort was initiated in 2008 as a grassroots inter-agency collaboration intended to identify the needs for such a system, assess the capabilities of current assets, and suggest priorities for future research and development. We will present a vision for an open, global GHGIS including latest analysis of system requirements, critical gaps, and relationship to related efforts at various agencies, the Group on Earth Observations, and the Intergovernmental Panel on Climate Change.

Food habits of American black bears as a metric for direct management of humanbear conflict in Yosemite Valley, Yosemite National Park, California

USGS Publications Warehouse

Greenleaf, S.S.; Matthews, S.M.; Wright, R.G.; Beecham, J.J.; Leithead, H.M.

2009-01-01

The management of human-American black bear (Ursus americanus) conflict has been of significant concern for Yosemite National Park (YNP) personnel since the 1920s. Park managers implemented the YNP Human-Bear Management Plan in 1975 in an effort to reduce human-bear conflicts, especially in the extensively developed Yosemite Valley (YV). We used scat analysis to estimate annual and seasonal food habits of black bears in YV during 2001-02. We assessed the success of efforts to reduce the availability of anthropogenic foods, including garbage, by examining changes in the diet compared to a study from 1974-78 (Graber 1981). We also quantified consumption of non-native fruit to address its possible contribution to human-bear conflicts. The annual percent volume of human-provided food and garbage in black bear scats in YV decreased from 21% to 6% between 1978 and 2002, indicating YNP efforts have been effective. We found high use of non-native apples by bears throughout YV. Non-native food sources could be contributing to habituation and food conditioning, given their proximity to developed areas of YV. We recommend that YNP managers continue to (1) adapt and improve their management tools to address changing circumstances, (2) quantify the success of new management tools, and (3) reduce the availability of non-native food sources. ?? 2009 International Association for Bear Research and Management.

Surveillance of Mosquitoes (Diptera: Culicidae) in Southern Iowa, 2016.

PubMed

Kovach, Kristofer B; Smith, Ryan C

2018-05-19

The mosquito fauna of Iowa has been extensively investigated over several decades, providing a wealth of information regarding species distributions, relative abundance, temporal activity patterns, and identifying vectors of medical importance. However, these investigations have had unequal coverage, leaving the mosquito fauna in some parts of the state, including southern Iowa, largely uncharacterized. With the heightened public health threat of Zika virus in the summer of 2016, greater emphasis was placed on surveying for two potential Zika virus vectors: Aedes (Stegomyia) albopictus (Skuse) and Aedes (Stegomyia) aegypti (Linnaeus). Southern Iowa became an area of interest due to the range of Ae. Albopictus, potentially extending into this part of the state. Employing CO2-baited Centers for Disease Control and Prevention light traps and BG-Sentinel traps, our targeted trapping efforts in southern Iowa did not yield either Ae. albopictus or Ae. aegypti. However, the geographical expansion of our trapping efforts did lend valuable insights into the mosquito fauna of southern Iowa. Mosquito species such as Aedes atropalpus (Coquillett), Culex erraticus (Dyar and Knab), and several Psorophora species once presumed rare or uncommon in the state were found to be more prevalent in this ecologically diverse region, augmenting our understanding of mosquito distributions in the state. Moreover, these surveillance efforts established baseline data for continued monitoring of the potential introduction and spread of invasive mosquito species in Iowa as part of an integrated mosquito management program.

"Efforts to Reprioritise the Agenda" in China: British American Tobacco's Efforts to Influence Public Policy on Secondhand Smoke in China.

PubMed

Muggli, Monique E; Lee, Kelley; Gan, Quan; Ebbert, Jon O; Hurt, Richard D

2008-12-23

Each year, 540 million Chinese are exposed to secondhand smoke (SHS), resulting in more than 100,000 deaths. Smoke-free policies have been demonstrated to decrease overall cigarette consumption, encourage smokers to quit, and protect the health of nonsmokers. However, restrictions on smoking in China remain limited and ineffective. Internal tobacco industry documents show that transnational tobacco companies (TTCs) have pursued a multifaceted strategy for undermining the adoption of restrictions on smoking in many countries. To understand company activities in China related to SHS, we analyzed British American Tobacco's (BAT's) internal corporate documents produced in response to litigation against the major cigarette manufacturers to understand company activities in China related to SHS. BAT has carried out an extensive strategy to undermine the health policy agenda on SHS in China by attempting to divert public attention from SHS issues towards liver disease prevention, pushing the so-called "resocialisation of smoking" accommodation principles, and providing "training" for industry, public officials, and the media based on BAT's corporate agenda that SHS is an insignificant contributor to the larger issue of air pollution. The public health community in China should be aware of the tactics previously used by TTCs, including efforts by the tobacco industry to co-opt prominent Chinese benevolent organizations, when seeking to enact stronger restrictions on smoking in public places.

QuakeML - An XML Schema for Seismology

NASA Astrophysics Data System (ADS)

Wyss, A.; Schorlemmer, D.; Maraini, S.; Baer, M.; Wiemer, S.

2004-12-01

We propose an extensible format-definition for seismic data (QuakeML). Sharing data and seismic information efficiently is one of the most important issues for research and observational seismology in the future. The eXtensible Markup Language (XML) is playing an increasingly important role in the exchange of a variety of data. Due to its extensible definition capabilities, its wide acceptance and the existing large number of utilities and libraries for XML, a structured representation of various types of seismological data should in our opinion be developed by defining a 'QuakeML' standard. Here we present the QuakeML definitions for parameter databases and further efforts, e.g. a central QuakeML catalog database and a web portal for exchanging codes and stylesheets.

Agricultural extension and mass media.

PubMed

Perraton, H

1983-12-01

To learn more about the use of the mass media for agricultural extension, the World Bank has considered the efforts of 2 units: INADES-formation in West Africa and the Extension Aids Branch of Malawi. The INADES-formation study focuses on Cameroon but also considers work in Rwanda and the Ivory Coast. Some general conclusions emerge from a comparison of the 2 organizations. Malawi operates an extension service which reaches farmers through extension agents, through farmer training centers, and through mass media. The Extension Aids Branch (EAB) has responsibility for its media work and broadcasts 4 1/2 hours of radio each week. Its 6 regular radio programs include a general program which interviews farmers, a music request program in which the music is interspersed with farming advice, a farming family serial, and a daily broadcast of agricultural news and information. The 17 cinema vans show some agricultural films, made by EAB, some entertainment films, and some government information films from departments other than the ministry of agriculture. EAB also has a well-developed program of research and evaluation of its own work. INADES-formation, the training section of INADES, works towards social and economic development of the population. It teaches peasant farmers and extension agents and does this through running face-to-face seminars, by publishing a magazine, "Agripromo," and through correspondence courses. In 1978-79 INADES-formation enrolled some 4500 farmers and extension agents as students. Both of these organizations work to teach farmers better agriculture techniques, and both were created in response to the fact that agricultural extension agents cannot meet all the farmers in their area. Despite the similarity of objective, there are differences in methods and philosophy. The EAB works in a single country and uses a variety of mass media, with print playing a minor role. INADES-formation is an international and nongovernmental organization and its use of mass media is almost confined to print. Its relationships with government are subtle. The available evidence confirms that the methods used by both institutions are effective. Farmers have learned much from the radio programs and the mobile vans of Malawi and from the correspondence courses of INADES-formation. The Extension Aids Branch makes a significant but most likely small change in the knowledge of a large number of farmers; INADES-formation makes a large change in the knowledge of a small number of farmers. The available evidence suggests that a variety of media, used in various ways, can be effective in supporting agricultural extension or in taking over some of its functions.

75 FR 12239 - Notice of Public Information Collection Being Reviewed by the Federal Communications Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-15

... FEDERAL COMMUNICATIONS COMMISSION Notice of Public Information Collection Being Reviewed by the Federal Communications Commission for Extension Under Delegated Authority, Comments Requested March 5, 2010. SUMMARY: The Federal Communications Commission, as part of its continuing effort to reduce...

A REVIEW OF NICKEL PLATING BATH LIFE EXTENSION, NICKEL RECOVERY & COPPER RECOVERY FROM NICKEL BATHS

EPA Science Inventory

For metal finishing operations to remain competitive and in compliance with environmental requirements, companies must focus their efforts on pollution prevention to reduce waste generation and disposal costs, limit liability and restore maximum profits. By applying the pollutio...

A Bridge to the Future: Observations on Building a Digital Library.

ERIC Educational Resources Information Center

Gaunt, Marianne I.

2002-01-01

The experience of Rutgers University Libraries illustrates the extensive planning, work effort, possibilities, and investment required to develop the digital library. Examines these key areas: organizational structure; staff development needs; facilities and the new digital infrastructure; metadata standards/interoperability; digital collection…

Challenges and opportunities with standardized monitoring for management decison-making

USDA-ARS?s Scientific Manuscript database

The importance of monitoring for adaptive management of rangelands has been well established. However, the actual use of monitoring data in rangeland management decisions has been modest despite extensive efforts to develop and implement monitoring programs from local to national scales. More effect...

20180318 - Curating and sharing structures and spectra for the environmental community (ACS Spring)

EPA Science Inventory

The increasing popularity of high mass accuracy non-target mass spectrometry methods has yielded extensive identification efforts based on spectral and chemical compound databases in the environmental community and beyond. Increasingly, new methods are relying on open data resour...

Regional sustainable environmental management: sustainability metrics research for decision makers

EPA Science Inventory

There are a number of established, scientifically supported metrics of sustainability. Many of the metrics are data intensive and require extensive effort to collect data and compute. Moreover, individual metrics may not capture all aspects of a system that are relevant to sust...

Development of a multidisciplinary approach to assess regional sustainability

EPA Science Inventory

There are a number of established, scientifically supported metrics of sustainability. Many of the metrics are data intensive and require extensive effort to collect data and compute the metrics. Moreover, individual metrics do not capture all aspects of a system that are relev...

EFFECTS OF CONAZOLE FUNGICIDES ON DEVELOPMENT AND PARTURITION IN THE RAT

EPA Science Inventory

Conazoles are fungicides used extensively in agriculture and as pharmaceuticals. As part of an effort to evaluate the changes in gene expression corresponding to reproductive toxicity, we examined the effects of three conazoles on pregnancy and neonates. Wistar Han rats were expo...

7 CFR 3403.4 - Three-phase program.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE SMALL BUSINESS INNOVATION RESEARCH GRANTS PROGRAM Program Description § 3403.4 Three-phase program. The Small Business Innovation Research Grants Program is... technical merit and feasibility of the proposed effort and the quality of performance of the small business...

Accessing Electronic Theses: Progress?

ERIC Educational Resources Information Center

Tennant, Roy

2000-01-01

Describes various ways by which universities provide access to their electronic theses and dissertations (ETDs), discussing UMI (University Microfilms International), XML (eXtensible Markup Language), and other formats. Discusses key leaders--national and international--in the ETD effort. Outlines the two main methods for locating ETDs. Presents a…

76 FR 51364 - Notification of a Public Teleconference of the Science Advisory Board Panel for the Review of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... extensive scientific studies, conferences and workshops. To guide the efforts of the GLRI, EPA and its... Web site at http://www.epa.gov/sab in advance of the meeting. Procedures for Providing Public Input...

78 FR 46594 - Extension of Agency Information Collection Activity Under OMB Review: Aviation Security Customer...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-01

... Information Collection Activity Under OMB Review: Aviation Security Customer Satisfaction Performance... surveying travelers to measure customer satisfaction of aviation security in an effort to more efficiently... Title: Aviation Security Customer Satisfaction Performance Measurement Passenger Survey. Type of Request...

75 FR 29567 - Extension of Agency Information Collection Activity Under OMB Review: Aviation Security Customer...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-26

... Information Collection Activity Under OMB Review: Aviation Security Customer Satisfaction Performance... surveying travelers to measure customer satisfaction of aviation security in an effort to more efficiently.... Information Collection Requirement OMB Control Number 1652-0013; Aviation Security Customer Satisfaction...

Sediment characteristics and microbial communities associated with methane production in a eutrophic reservoir

EPA Science Inventory

Methane (CH4), a potent greenhouse gas, is known to be produced and emitted from freshwater systems. Recently, extensive efforts have been directed toward quantifyingmethane emissions fromthese ecosystems, while additional research has focused on factors that may influence emissi...

Estimating carbon fluxes on small rotationally grazed pastures

USDA-ARS?s Scientific Manuscript database

Satellite-based Normalized Difference Vegetation Index (NDVI) data have been extensively used for estimating gross primary productivity (GPP) and yield of grazing lands throughout the world. Large-scale estimates of GPP are a necessary component of efforts to monitor the soil carbon balance of grazi...

Towards Cooperative Learning in Elementary School Physical Education

ERIC Educational Resources Information Center

Kirchner, Glenn

2005-01-01

The extensive amount of research evidence, at all levels of education and with all subject areas, consistently indicates that cooperative learning results in higher achievement, increased positive interpersonal relationships, and higher self-esteem than competitive or individualistic efforts. In physical education, individualistic learning is an…

Landmarks in the historical development of twenty first century food processing technologies.

PubMed

Misra, N N; Koubaa, Mohamed; Roohinejad, Shahin; Juliano, Pablo; Alpas, Hami; Inácio, Rita S; Saraiva, Jorge A; Barba, Francisco J

2017-07-01

Over a course of centuries, various food processing technologies have been explored and implemented to provide safe, fresher-tasting and nutritive food products. Among these technologies, application of emerging food processes (e.g., cold plasma, pressurized fluids, pulsed electric fields, ohmic heating, radiofrequency electric fields, ultrasonics and megasonics, high hydrostatic pressure, high pressure homogenization, hyperbaric storage, and negative pressure cavitation extraction) have attracted much attention in the past decades. This is because, compared to their conventional counterparts, novel food processes allow a significant reduction in the overall processing times with savings in energy consumption, while ensuring food safety, and ample benefits for the industry. Noteworthily, industry and university teams have made extensive efforts for the development of novel technologies, with sound scientific knowledge of their effects on different food materials. The main objective of this review is to provide a historical account of the extensive efforts and inventions in the field of emerging food processing technologies since their inception to present day. Copyright © 2017 Elsevier Ltd. All rights reserved.

Heat transfer with hockey-stick steam generator. [LMFBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moody, E; Gabler, M J

1977-11-01

The hockey-stick modular design concept is a good answer to future needs for reliable, economic LMFBR steam generators. The concept was successfully demonstrated in the 30 Mwt MSG test unit; scaled up versions are currently in fabrication for CRBRP usage, and further scaling has been accomplished for PLBR applications. Design and performance characteristics are presented for the three generations of hockey-stick steam generators. The key features of the design are presented based on extensive analytical effort backed up by extensive ancillary test data. The bases for and actual performance evaluations are presented with emphasis on the CRBRP design. The designmore » effort on these units has resulted in the development of analytical techniques that are directly applicable to steam generators for any LMFBR application. In conclusion, the hockey-stick steam generator concept has been proven to perform both thermally and hydraulically as predicted. The heat transfer characteristics are well defined, and proven analytical techniques are available as are personnel experienced in their use.« less

Japanese Encephalitis—A Pathological and Clinical Perspective

PubMed Central

Ghosh, Debapriya; Basu, Anirban

2009-01-01

Japanese encephalitis (JE) is the leading form of viral encephalitis in Asia. It is caused by the JE virus (JEV), which belongs to the family Flaviviridae. JEV is endemic to many parts of Asia, where periodic outbreaks take hundreds of lives. Despite the catastrophes it causes, JE has remained a tropical disease uncommon in the West. With rapid globalization and climatic shift, JEV has started to emerge in areas where the threat was previously unknown. Scientific evidence predicts that JEV will soon become a global pathogen and cause of worldwide pandemics. Although some research documents JEV pathogenesis and drug discovery, worldwide awareness of the need for extensive research to deal with JE is still lacking. This review focuses on the exigency of developing a worldwide effort to acknowledge the prime importance of performing an extensive study of this thus far neglected tropical viral disease. This review also outlines the pathogenesis, the scientific efforts channeled into develop a therapy, and the outlook for a possible future breakthrough addressing this killer disease. PMID:19787040

Development Roadmap of an Evolvable and Extensible Multi-Mission Telecom Planning and Analysis Framework

NASA Technical Reports Server (NTRS)

Cheung, Kar-Ming; Tung, Ramona H.; Lee, Charles H.

2003-01-01

In this paper, we describe the development roadmap and discuss the various challenges of an evolvable and extensible multi-mission telecom planning and analysis framework. Our long-term goal is to develop a set of powerful flexible telecommunications analysis tools that can be easily adapted to different missions while maintain the common Deep Space Communication requirements. The ability of re-using the DSN ground models and the common software utilities in our adaptations has contributed significantly to our development efforts measured in terms of consistency, accuracy, and minimal effort redundancy, which can translate into shorter development time and major cost savings for the individual missions. In our roadmap, we will address the design principles, technical achievements and the associated challenges for following telecom analysis tools (i) Telecom Forecaster Predictor - TFP (ii) Unified Telecom Predictor - UTP (iii) Generalized Telecom Predictor - GTP (iv) Generic TFP (v) Web-based TFP (vi) Application Program Interface - API (vii) Mars Relay Network Planning Tool - MRNPT.

Toward a Predictive Understanding of Earth’s Microbiomes to Address 21st Century Challenges

PubMed Central

Blaser, Martin J.; Cardon, Zoe G.; Cho, Mildred K.; Dangl, Jeffrey L.; Green, Jessica L.; Knight, Rob; Maxon, Mary E.; Northen, Trent R.; Pollard, Katherine S.

2016-01-01

ABSTRACT Microorganisms have shaped our planet and its inhabitants for over 3.5 billion years. Humankind has had a profound influence on the biosphere, manifested as global climate and land use changes, and extensive urbanization in response to a growing population. The challenges we face to supply food, energy, and clean water while maintaining and improving the health of our population and ecosystems are significant. Given the extensive influence of microorganisms across our biosphere, we propose that a coordinated, cross-disciplinary effort is required to understand, predict, and harness microbiome function. From the parallelization of gene function testing to precision manipulation of genes, communities, and model ecosystems and development of novel analytical and simulation approaches, we outline strategies to move microbiome research into an era of causality. These efforts will improve prediction of ecosystem response and enable the development of new, responsible, microbiome-based solutions to significant challenges of our time. PMID:27178263

Toward a Predictive Understanding of Earth's Microbiomes to Address 21st Century Challenges.

PubMed

Blaser, Martin J; Cardon, Zoe G; Cho, Mildred K; Dangl, Jeffrey L; Donohue, Timothy J; Green, Jessica L; Knight, Rob; Maxon, Mary E; Northen, Trent R; Pollard, Katherine S; Brodie, Eoin L

2016-05-13

Microorganisms have shaped our planet and its inhabitants for over 3.5 billion years. Humankind has had a profound influence on the biosphere, manifested as global climate and land use changes, and extensive urbanization in response to a growing population. The challenges we face to supply food, energy, and clean water while maintaining and improving the health of our population and ecosystems are significant. Given the extensive influence of microorganisms across our biosphere, we propose that a coordinated, cross-disciplinary effort is required to understand, predict, and harness microbiome function. From the parallelization of gene function testing to precision manipulation of genes, communities, and model ecosystems and development of novel analytical and simulation approaches, we outline strategies to move microbiome research into an era of causality. These efforts will improve prediction of ecosystem response and enable the development of new, responsible, microbiome-based solutions to significant challenges of our time. Copyright © 2016 Blaser et al.

The Wisconsin Early Childhood Obesity Prevention Initiative: An Example of Statewide Collective Impact.

PubMed

Meinen, Amy; Hilgendorf, Amy; Korth, Amy L; Christens, Brian D; Breuer, Catherine; Joyner, Hilary; Polzin, Molle; Adams, Alexandra; Wolfe, Daithi; Braun, Abbe; Hoiting, Jill; Paulson, Jeanette; Cullen, Bridget; Stader, Kelli

2016-11-01

The Wisconsin Early Childhood Obesity Prevention Initiative (Initiative), established in 2007, seeks to address and prevent obesity in the early care and education system through nutrition and physical activity environmental and policy changes. The collaborative includes professionals from 3 state of Wisconsin Departments, the University of Wisconsin-Extension, the University of Wisconsin-Madison, and public health and early care and education organizations. This paper explores the efforts of the Initiative to advance our understanding of collective impact in practice and its value to health promotion efforts. Evaluators conducted a mixed methods case study to evaluate the application of collective impact principles by the Initiative. This included a survey of Initiative partners, review of archival documents, and qualitative interviews with Initiative leaders. Initiative partners noted progress in establishing the conditions for collective impact. Archival documents and interviews describe both formal and informal practices that helped set a common agenda, align and coordinate partner activities, and promote communication among Initiative leaders. Results also detail the important current and potential roles of “backbone” staff from healthTIDE to support the Initiative. Additionally, results suggest particularly challenging aspects of the Initiative’s impact model related to shared measurement and broader stakeholder communication. While the Initiative is still setting in place the conditions for collective impact, it has achieved significant policy, systems, and environment changes since its formation. Inclusion of nutrition and physical activity criteria in the state’s quality rating improvement system for child care centers is one of its outcomes. This case study offers several important insights about the application of collective impact in health promotion efforts, particularly in relation to the transition from previous collaborative activities, the value of establishing a clear common agenda among partners, the roles of backbone staff, and time and partner relationships in collective impact.

Rabies in Greece; historical perspectives in view of the current re-emergence in wild and domestic animals.

PubMed

Tsiodras, Sotirios; Korou, Laskarina-Maria; Tzani, Myrsini; Tasioudi, Konstantia E; Kalachanis, Kostantinos; Mangana-Vougiouka, Olga; Rigakos, George; Dougas, George; Seimenis, Aristarchos M; Kontos, Vassileios

2014-01-01

Greece has been rabies free since 1987 while no human cases have been seen since 1970. The re-emergence of rabies in Northern Greece during 2012-2013 in wild and domestic animals prompted a systematic review of historical evidence of the presence of the disease in the country from ancient years till the present. Historical data is presented along with efforts to prevent disease in animals and humans especially during the high prevalent periods in the country in the mid-20th century. These efforts serve as a guide to current extensive efforts to prevent spread especially in the wild and domestic animal populations. Copyright © 2014 Elsevier Ltd. All rights reserved.

Advanced Wireless Sensor Nodes - MSFC

NASA Technical Reports Server (NTRS)

Varnavas, Kosta; Richeson, Jeff

2017-01-01

NASA field center Marshall Space Flight Center (Huntsville, AL), has invested in advanced wireless sensor technology development. Developments for a wireless microcontroller back-end were primarily focused on the commercial Synapse Wireless family of devices. These devices have many useful features for NASA applications, good characteristics and the ability to be programmed Over-The-Air (OTA). The effort has focused on two widely used sensor types, mechanical strain gauges and thermal sensors. Mechanical strain gauges are used extensively in NASA structural testing and even on vehicle instrumentation systems. Additionally, thermal monitoring with many types of sensors is extensively used. These thermal sensors include thermocouples of all types, resistive temperature devices (RTDs), diodes and other thermal sensor types. The wireless thermal board will accommodate all of these types of sensor inputs to an analog front end. The analog front end on each of the sensors interfaces to the Synapse wireless microcontroller, based on the Atmel Atmega128 device. Once the analog sensor output data is digitized by the onboard analog to digital converter (A/D), the data is available for analysis, computation or transmission. Various hardware features allow custom embedded software to manage battery power to enhance battery life. This technology development fits nicely into using numerous additional sensor front ends, including some of the low-cost printed circuit board capacitive moisture content sensors currently being developed at Auburn University.

IMAPS Device Packaging Conference 2017 - Engineered Micro Systems & Devices Track

NASA Technical Reports Server (NTRS)

Varnavas, Kosta

2017-01-01

NASA field center Marshall Space Flight Center (Huntsville, AL), has invested in advanced wireless sensor technology development. Developments for a wireless microcontroller back-end were primarily focused on the commercial Synapse Wireless family of devices. These devices have many useful features for NASA applications, good characteristics and the ability to be programmed Over-The-Air (OTA). The effort has focused on two widely used sensor types, mechanical strain gauges and thermal sensors. Mechanical strain gauges are used extensively in NASA structural testing and even on vehicle instrumentation systems. Additionally, thermal monitoring with many types of sensors is extensively used. These thermal sensors include thermocouples of all types, resistive temperature devices (RTDs), diodes and other thermal sensor types. The wireless thermal board will accommodate all of these types of sensor inputs to an analog front end. The analog front end on each of the sensors interfaces to the Synapse wireless microcontroller, based on the Atmel Atmega128 device. Once the analog sensor output data is digitized by the onboard analog to digital converter (A/D), the data is available for analysis, computation or transmission. Various hardware features allow custom embedded software to manage battery power to enhance battery life. This technology development fits nicely into using numerous additional sensor front ends, including some of the low-cost printed circuit board capacitive moisture content sensors currently being developed at Auburn University.

Differential effects of power training versus functional task practice on compensation and restoration of arm function after stroke.

PubMed

Corti, Manuela; McGuirk, Theresa E; Wu, Samuel S; Patten, Carolynn

2012-09-01

Improved upper-extremity (UE) movement with stroke rehabilitation may involve restoration of more normal or development of compensatory movement patterns. The authors investigated the differential effects of functional task practice (FTP) and dynamic resistance training (POWER) on clinical function and reaching kinematics in an effort to distinguish between mechanisms of gains. A total of 14 hemiparetic individuals were randomly assigned to 10 weeks of either FTP or POWER and then crossed over to 10 weeks of the alternate treatment. Treatment order A was FTP followed by POWER, whereas treatment order B was POWER followed by FTP. Evaluation before and after each treatment block included a battery of clinical evaluations and kinematics of paretic UE functional reach to grasp. Both FTP and POWER improved movement accuracy, as revealed by a shift toward normal, including fewer submovements and reduced reach-path ratio. However, active range of motion revealed differential treatment effects. Shoulder flexion and elbow extension decreased with FTP and were associated with increased trunk displacement. In contrast, shoulder flexion and elbow extension excursion increased with POWER and were associated with significantly reduced trunk displacement. Treatment order B (POWER followed by FTP) revealed greater overall improvements. FTP increases compensatory movement patterns to improve UE function. POWER leads to more normal movement patterns. POWER prior to FTP may enhance the benefits of repetitive task practice.

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

PubMed Central

Hart, Gerald W.; Slawson, Chad; Ramirez-Correa, Genaro; Lagerlof, Olof

2012-01-01

O-GlcNAcylation is the addition of β-D-N-acetylglucosamine to serine or threonine residues of nuclear and cytoplasmic proteins. O-linked N-acetylglucosamine (O-GlcNAc) was not discovered until the early 1980s and still remains difficult to detect and quantify. Nonetheless, O-GlcNAc is highly abundant and cycles on proteins with a timescale similar to protein phosphorylation. O-GlcNAc occurs in organisms ranging from some bacteria to protozoans and metazoans, including plants and nematodes up the evolutionary tree to man. O-GlcNAcylation is mostly on nuclear proteins, but it occurs in all intracellular compartments, including mitochondria. Recent glycomic analyses have shown that O-GlcNAcylation has surprisingly extensive cross talk with phosphorylation, where it serves as a nutrient/stress sensor to modulate signaling, transcription, and cytoskeletal functions. Abnormal amounts of O-GlcNAcylation underlie the etiology of insulin resistance and glucose toxicity in diabetes, and this type of modification plays a direct role in neurodegenerative disease. Many oncogenic proteins and tumor suppressor proteins are also regulated by O-GlcNAcylation. Current data justify extensive efforts toward a better understanding of this invisible, yet abundant, modification. As tools for the study of O-GlcNAc become more facile and available, exponential growth in this area of research will eventually take place. PMID:21391816

Computer simulation and performance assessment of the packet-data service of the Aeronautical Mobile Satellite Service (AMSS)

NASA Technical Reports Server (NTRS)

Ferzali, Wassim; Zacharakis, Vassilis; Upadhyay, Triveni; Weed, Dennis; Burke, Gregory

1995-01-01

The ICAO Aeronautical Mobile Communications Panel (AMCP) completed the drafting of the Aeronautical Mobile Satellite Service (AMSS) Standards and Recommended Practices (SARP's) and the associated Guidance Material and submitted these documents to ICAO Air Navigation Commission (ANC) for ratification in May 1994. This effort, encompassed an extensive, multi-national SARP's validation. As part of this activity, the US Federal Aviation Administration (FAA) sponsored an effort to validate the SARP's via computer simulation. This paper provides a description of this effort. Specifically, it describes: (1) the approach selected for the creation of a high-fidelity AMSS computer model; (2) the test traffic generation scenarios; and (3) the resultant AMSS performance assessment. More recently, the AMSS computer model was also used to provide AMSS performance statistics in support of the RTCA standardization activities. This paper describes this effort as well.

California's "5 a day--for better health!" campaign: an innovative population-based effort to effect large-scale dietary change.

PubMed

Foerster, S B; Kizer, K W; Disogra, L K; Bal, D G; Krieg, B F; Bunch, K L

1995-01-01

The annual toll of diet-related diseases in the United States is similar to that taken by tobacco, but less progress has been achieved in reaching the Public Health Service's Healthy People 2000 objectives for improving food consumption than for reducing tobacco use. In 1988, the California Department of Health Services embarked upon an innovative multi-year social marketing program to increase fruit and vegetable consumption. The 5 a Day--for Better Health! Campaign had several distinctive features, including its simple, positive, behavior-specific message to eat 5 servings of fruits and vegetables every day as part of a low-fat, high fiber diet; its use of mass media; its partnership between the state health department and the produce and supermarket industries; and its extensive use of point-of-purchase messages. Over its nearly three years of operation in California, the 5 a Day Campaign appears to have raised public awareness that fruits and vegetables help reduce cancer risk, increased fruit and vegetable consumption in major population segments, and created an ongoing partnership between public health and agribusiness that has allowed extension of the campaign to other population segments, namely children and Latino adults. In 1991 the campaign was adopted as a national initiative by the National Cancer Institute and the Produce for Better Health Foundation. By 1994, over 700 industry organizations and 48 states, territories, and the District of Columbia were licensed to participate. Preventive medicine practitioners and others involved in health promotion may build upon the 5 a Day Campaign experience in developing and implementing efforts to reach the nation's dietary goals.

Preliminary Results From NASA's Space Solar Power Exploratory Research and Technology Program

NASA Technical Reports Server (NTRS)

Howell, Joe T.; Mankins, John C.

2000-01-01

Large solar power satellite (SPS) systems that might provide base load power into terrestrial markets were examined extensively in the 1970s by the US Department of Energy (DOE) and the National Aeronautics and Space Administration (NASA). Following a hiatus of about 15 years, the subject of space solar power (SSP) was reexamined by NASA from 1995-1997 in the "fresh look" study, and during 1998 in an SSP "concept definition study". As a result of these efforts, during 1999-2000, NASA has been conducting the SSP Exploratory Research and Technology (SERT) program. The goal of the SERT activity has been to conduct preliminary strategic technology research and development to enable large, multi-megawatt SSP systems and wireless power transmission (WPT) for government missions and commercial markets (in-space and terrestrial). In pursuing that goal, the SERT: (1) refined and modeled systems approaches for the utilization of SSP concepts and technologies, ranging from the near-term (e.g., for space science, exploration and commercial space applications) to the far-term (e.g., SSP for terrestrial markets), including systems concepts, architectures, technology, infrastructure (e.g. transportation), and economics; (2) conducted technology research, development and demonstration activities to produce "proof-of-concept" validation of critical SSP elements for both nearer and farther-term applications; and (3) engendered the beginnings of partnerships (nationally and internationally) that could be expanded, as appropriate, to pursue later SSP technology and applications. Through these efforts, the SERT should allow better informed future decisions regarding further SSP and related technology research and development investments by both NASA and prospective partners, and guide further definition of technology roadmaps - including performance objectives, resources and schedules, as well as "multi-purpose" applications (e.g., commerce, science, and government). This paper presents preliminary results from the SERT effort at a summary level, including the study approach, SPS concepts, applications findings, and concludes with a revised assessment of the prospects for solar power satellites using SSP technologies and systems.

A national evaluation of a dissemination and implementation initiative to enhance primary care practice capacity and improve cardiovascular disease care: the ESCALATES study protocol.

PubMed

Cohen, Deborah J; Balasubramanian, Bijal A; Gordon, Leah; Marino, Miguel; Ono, Sarah; Solberg, Leif I; Crabtree, Benjamin F; Stange, Kurt C; Davis, Melinda; Miller, William L; Damschroder, Laura J; McConnell, K John; Creswell, John

2016-06-29

The Agency for Healthcare Research and Quality (AHRQ) launched the EvidenceNOW Initiative to rapidly disseminate and implement evidence-based cardiovascular disease (CVD) preventive care in smaller primary care practices. AHRQ funded eight grantees (seven regional Cooperatives and one independent national evaluation) to participate in EvidenceNOW. The national evaluation examines quality improvement efforts and outcomes for more than 1500 small primary care practices (restricted to those with fewer than ten physicians per clinic). Examples of external support include practice facilitation, expert consultation, performance feedback, and educational materials and activities. This paper describes the study protocol for the EvidenceNOW national evaluation, which is called Evaluating System Change to Advance Learning and Take Evidence to Scale (ESCALATES). This prospective observational study will examine the portfolio of EvidenceNOW Cooperatives using both qualitative and quantitative data. Qualitative data include: online implementation diaries, observation and interviews at Cooperatives and practices, and systematic assessment of context from the perspective of Cooperative team members. Quantitative data include: practice-level performance on clinical quality measures (aspirin prescribing, blood pressure and cholesterol control, and smoking cessation; ABCS) collected by Cooperatives from electronic health records (EHRs); practice and practice member surveys to assess practice capacity and other organizational and structural characteristics; and systematic tracking of intervention delivery. Quantitative, qualitative, and mixed methods analyses will be conducted to examine how Cooperatives organize to provide external support to practices, to compare effectiveness of the dissemination and implementation approaches they implement, and to examine how regional variations and other organization and contextual factors influence implementation and effectiveness. ESCALATES is a national evaluation of an ambitious large-scale dissemination and implementation effort focused on transforming smaller primary care practices. Insights will help to inform the design of national health care practice extension systems aimed at supporting practice transformation efforts in the USA. NCT02560428 (09/21/15).

Methyl Chloroform Elimination from the Production of Space Shuttle Sold Rocket Motors

NASA Technical Reports Server (NTRS)

Golde, Rick P.; Burt, Rick; Key, Leigh

1997-01-01

Thiokol Space Operations manufactures the Reusable Solid Rocket Motors used to launch America's fleet of Space Shuttles. In 1989, Thiokol used more than 1.4 Mlb of methyl chloroform to produce rocket motors. The ban placed by the Environmental Protection Agency on the sale of methyl chloroform had a significant effect on future Reusable Solid Rocket Motor production. As a result, changes in the materials and processes became necessary. A multiphased plan was established by Thiokol in partnership with NASA's Marshall Space Flight Center to eliminate the use of methyl chloroform in the Reusable Solid Rocket Motor production process. Because of the extensive scope of this effort, the plan was phased to target the elimination of the majority of methyl chloroform use (90 percent) by January 1, 1996, the 3 Environmental Protection Agency deadline. Referred to as Phase I, this effort includes the elimination of two large vapor degreasers, grease diluent processes, and propellant tooling handcleaning using methyl chloroform. Meanwhile, a request was made for an essential use exemption to allow the continued use of the remaining 10 percent of methyl chloroform after the 1996 deadline, while total elimination was pursued for this final, critical phase (Phase II). This paper provides an update to three previous presentations prepared for the 1993, 1994, and 1995 CFC/Halon Alternative Conferences, and will outline the overall Ozone Depleting Compounds Elimination Program from the initial phases through the final testing and implementation phases, including facility and equipment development. Processes and materials to be discussed include low-pressure aqueous wash systems, high-pressure water blast systems- environmental shipping containers, aqueous and semi-aqueous cleaning solutions, and bond integrity and inspection criteria. Progress toward completion of facility implementation and lessons learned during the scope of the program, as well as the current development efforts and basic requirements of future methyl chloroform handcleaning elimination, will also be outlined.

Filling the Knowledge Gap that Exists Between the Public and Its Leaders and Climate Science Experts

NASA Astrophysics Data System (ADS)

Mandia, S. A.; Abraham, J. P.; Dash, J. W.; Ashley, M. C.

2012-12-01

There is a gap between what the general public and its elected leaders know about climate change and what climate scientists understand about this critical issue. One such effort by the authors to fill this gap is the Climate Science Rapid Response Team (CSRRT), formed in November 2010 to provide rapid, high-quality climate science information to international news media and lawmakers. Currently, CSRRT has enlisted 250 top climate scientists, including those with expertise on the economics and policy matters, whom are committed to be on call for climate-related inquiries. CSRRT has responded to more than 300 inquiries including, from among many others, The White House, Congress, and local governmental officials, major television and cable news networks, radio programs, mainstream international newspaper outlets, and a broad range of online news providers. CSRRT scientists have also been provided extensive communication training to help encourage the use of jargon-free language so that clear communication with the broader public can be more successful. In addition to the CSRRT, the authors have undertaken several behind the scenes initiatives to increase public awareness about climate change. This presentation will describe the operation of CSRRT along with some of its highlights, as well as offer a peek into the authors' less public efforts that have had a major impact on various climate-related news stories and policy.

Postharvest technology for developing countries: challenges and opportunities in research, outreach and advocacy.

PubMed

Kitinoja, Lisa; Saran, Sunil; Roy, Susanta K; Kader, Adel A

2011-03-15

This article discusses the needs and challenges of developing good, science-based, simple methods for postharvest handling that can be made available in developing countries. Some of the traditional challenges have been successfully met (i.e. identifying causes and sources of losses for key crops, identifying many potential postharvest technologies of practical use for reducing losses), but many challenges remain. These include the characterization of indigenous crops in terms of their unique postharvest physiology (e.g. respiration rate, susceptibility to water loss, chilling sensitivity, ethylene sensitivity), ascertaining the differences between handling recommendations made for well-known varieties and the needs of local varieties of crops, and determining cost effectiveness of scale-appropriate postharvest technologies in each locale and for each crop. Key issues include building capacity at the local level in postharvest science, university teaching and extension, and continued adaptive research efforts to match emerging postharvest technologies to local needs as these continue to change over time. Development of appropriate postharvest technology relies upon many disciplines that are relevant to the overall success of horticulture, i.e. plant biology, engineering, agricultural economics, food processing, nutrition, food safety, and environmental conservation. The expanding pool of new information derived from postharvest research and outreach efforts in these areas can lead in many directions which are likely to have an impact on relieving poverty in developing countries. Copyright © 2011 Society of Chemical Industry.

Translation of proteomic biomarkers into FDA approved cancer diagnostics: issues and challenges

PubMed Central

2013-01-01

Tremendous efforts have been made over the past few decades to discover novel cancer biomarkers for use in clinical practice. However, a striking discrepancy exists between the effort directed toward biomarker discovery and the number of markers that make it into clinical practice. One of the confounding issues in translating a novel discovery into clinical practice is that quite often the scientists working on biomarker discovery have limited knowledge of the analytical, diagnostic, and regulatory requirements for a clinical assay. This review provides an introduction to such considerations with the aim of generating more extensive discussion for study design, assay performance, and regulatory approval in the process of translating new proteomic biomarkers from discovery into cancer diagnostics. We first describe the analytical requirements for a robust clinical biomarker assay, including concepts of precision, trueness, specificity and analytical interference, and carryover. We next introduce the clinical considerations of diagnostic accuracy, receiver operating characteristic analysis, positive and negative predictive values, and clinical utility. We finish the review by describing components of the FDA approval process for protein-based biomarkers, including classification of biomarker assays as medical devices, analytical and clinical performance requirements, and the approval process workflow. While we recognize that the road from biomarker discovery, validation, and regulatory approval to the translation into the clinical setting could be long and difficult, the reward for patients, clinicians and scientists could be rather significant. PMID:24088261

The "Performance of Rotavirus and Oral Polio Vaccines in Developing Countries" (PROVIDE) study: description of methods of an interventional study designed to explore complex biologic problems.

PubMed

Kirkpatrick, Beth D; Colgate, E Ross; Mychaleckyj, Josyf C; Haque, Rashidul; Dickson, Dorothy M; Carmolli, Marya P; Nayak, Uma; Taniuchi, Mami; Naylor, Caitlin; Qadri, Firdausi; Ma, Jennie Z; Alam, Masud; Walsh, Mary Claire; Diehl, Sean A; Petri, William A

2015-04-01

Oral vaccines appear less effective in children in the developing world. Proposed biologic reasons include concurrent enteric infections, malnutrition, breast milk interference, and environmental enteropathy (EE). Rigorous study design and careful data management are essential to begin to understand this complex problem while assuring research subject safety. Herein, we describe the methodology and lessons learned in the PROVIDE study (Dhaka, Bangladesh). A randomized clinical trial platform evaluated the efficacy of delayed-dose oral rotavirus vaccine as well as the benefit of an injectable polio vaccine replacing one dose of oral polio vaccine. This rigorous infrastructure supported the additional examination of hypotheses of vaccine underperformance. Primary and secondary efficacy and immunogenicity measures for rotavirus and polio vaccines were measured, as well as the impact of EE and additional exploratory variables. Methods for the enrollment and 2-year follow-up of a 700 child birth cohort are described, including core laboratory, safety, regulatory, and data management practices. Intense efforts to standardize clinical, laboratory, and data management procedures in a developing world setting provide clinical trials rigor to all outcomes. Although this study infrastructure requires extensive time and effort, it allows optimized safety and confidence in the validity of data gathered in complex, developing country settings. © The American Society of Tropical Medicine and Hygiene.

A Central American Perspective on Teaching about the United Nations.

ERIC Educational Resources Information Center

Ordonez, Eleonora

1994-01-01

Contends that the United Nations actively works to improve living conditions in Honduras. Discusses United Nations efforts to improve education through teacher education. Asserts that, although the United Nations has extensive operations in Honduras, education about the UN in Honduran schools is superficial. (CFR)

49 CFR 377.203 - Extension of credit to shippers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... payment of the full, nondiscounted rate instead of the discounted rate otherwise applicable. The difference between the discount and the full rate constitutes a carrier's liquidated damages for its collection effort. Under this method the tariff shall identify the discount rates that are subject to the...

TREATMENT OF ARSENIC AND METALS IN GROUND WATER USING A COMPOST/ZVI PRB

EPA Science Inventory

One of Region 4's Regional Applied Research Efforts (RARE) projects resulted in two different studies on cleaning up the Columbia Nitrogen Superfund Site located in Charleston, SC. This site is extensively contaminated with pyrite and elemental sulfur used in phosphate fertilize...

Survey and hydrogeology of Carroll Cave

USDA-ARS?s Scientific Manuscript database

Carroll Cave, located in Camden County, Missouri, is the largest known cave formed in the Gasconade Dolomite of the Salem Plateau. Despite extensive visitation over the last 50 years and multiple survey efforts, a comprehensive map of the cave has never been produced. In 2002, the Carroll Cave Conse...

Students Can Control Their Emotions

ERIC Educational Resources Information Center

Harati, Saba; Parsa, Nasrin Arian

2014-01-01

As emotional intelligence contributes extensively in people's lives, it can also find some significance in language teaching. From this perspective, it is inevitable for teachers to know how to improve students' emotional intelligence. This paper made an effort to provide procedures to develop emotional intelligence. Although success has various…

Getting More Scientists to Revamp Teaching

ERIC Educational Resources Information Center

Vicens, Quentin; Caspersen, Michael E.

2014-01-01

Despite extensive evidence in favor of student-centered teaching practices over traditional lecturing, most science faculty do not embrace these modes of instruction. Professional development efforts are plentiful, but they can lack in impact or scalability, or both. The factors that determine professional development quality within a research…

47 CFR 22.907 - Coordination of channel usage.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MOBILE SERVICES Cellular Radiotelephone Service § 22.907 Coordination of channel usage. Licensees in the... to suggest extensive changes to or redesign other licensees' cellular systems. Licensees must make reasonable efforts to avoid blocking the growth of other cellular systems that are likely to need additional...

ESEA at 50

ERIC Educational Resources Information Center

Jennings, Jack

2015-01-01

The author draws on his extensive experience helping lead Congress's education efforts and later a highly respected education research concern to propose a new approach to federal education policy that expands and transforms the federal role. This new approach would significantly expand federal aid to schools that is not restricted to particular…

Temporal Responses of Coastal Hypoxia to Nutrient Loading and Physical Controls.

EPA Science Inventory

The incidence and intensity of hypoxic waters in coastal aquatic ecosystems has been expanding in recent decades coincident with eutrophication of the coastal zone. Because of the negative effects hypoxia has on many organisms, extensive efforts have been made to reduce the size ...

Pioneers in Alaskan Adult Education.

ERIC Educational Resources Information Center

Niemi, John A.

Serious problems were posed by North American pioneer efforts to force their traditions on Eskimos, Indians, and Aleuts. Fortunately, other pioneers, such as home economists and district agents with the University of Alaska Cooperative Extension Service, responded to villagers' home and community needs. The University of Alaska also pioneered in…

75 FR 38775 - Proposed Information Collection; Comment Request; Generic Clearance for Customer Satisfaction...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-06

...; Generic Clearance for Customer Satisfaction Research AGENCY: U.S. Census Bureau. ACTION: Notice. SUMMARY... Bureau is requesting an extension of the generic clearance to conduct customer satisfaction research... on feedback from its various customer satisfaction research efforts. Each research design is reviewed...

The Effects of Group Diffusion of Cognitive Effort on Attitudes: An Information-Processing View.

ERIC Educational Resources Information Center

Petty, Richard E.; And Others

1980-01-01

Two experiments were conducted to test the hypothesis that persons process a stimulus less extensively when they are part of a group that is responsible for the task than when they are individually responsible. Subjects were college students. (Author/MP)

Expanding the Graduate Education Experience at Scripps Institution of Oceanography, UC San Diego

NASA Astrophysics Data System (ADS)

Peach, C. L.; Kilb, D. L.; Zmarzly, D.; Abeyta, E.

2016-02-01

Emerging career pathways for graduate students in earth, ocean and climate sciences increasingly require skills in teaching and communication. This is true of academic careers, in which demonstrated teaching skills make applicants for faculty positions far more competitive, and traditionally less conventional careers outside of academia that require cross-disciplinary collaboration and/or communication to audiences not directly involved in science research (e.g. policy makers, educators, the public). Yet most graduate education programs provide little to no opportunity or incentive for young investigators to develop and hone these skills, and graduate students are often discouraged from deviating from the traditional "research apprenticeship" model during their graduate education. At Scripps, the Birch Aquarium at Scripps, and UC San Diego Extension, we are developing new ways to integrate teaching, communication, and outreach into our graduate education program, thus broadening the scope of graduate training and better serving the needs and evolving career aspirations of our graduate students. This effort is an integral part of our overall outreach strategy a Scripps in which we seek to combine high quality STEM outreach and teaching with opportunities for Scripps graduate students to put their teaching and communications training into practice. The overall effort is a "win-win" both for our students and for the highly diverse K-16 community in San Diego County. In this talk we will summarize the programmatic efforts currently underway at Scripps, our strategic collaboration with UCSD Extension, which is expanding the capacity and reach of our integrated program, and our plans for sustaining these efforts for the long term.

Anniversary Paper: History and status of CAD and quantitative image analysis: The role of Medical Physics and AAPM

PubMed Central

Giger, Maryellen L.; Chan, Heang-Ping; Boone, John

2008-01-01

The roles of physicists in medical imaging have expanded over the years, from the study of imaging systems (sources and detectors) and dose to the assessment of image quality and perception, the development of image processing techniques, and the development of image analysis methods to assist in detection and diagnosis. The latter is a natural extension of medical physicists’ goals in developing imaging techniques to help physicians acquire diagnostic information and improve clinical decisions. Studies indicate that radiologists do not detect all abnormalities on images that are visible on retrospective review, and they do not always correctly characterize abnormalities that are found. Since the 1950s, the potential use of computers had been considered for analysis of radiographic abnormalities. In the mid-1980s, however, medical physicists and radiologists began major research efforts for computer-aided detection or computer-aided diagnosis (CAD), that is, using the computer output as an aid to radiologists—as opposed to a completely automatic computer interpretation—focusing initially on methods for the detection of lesions on chest radiographs and mammograms. Since then, extensive investigations of computerized image analysis for detection or diagnosis of abnormalities in a variety of 2D and 3D medical images have been conducted. The growth of CAD over the past 20 years has been tremendous—from the early days of time-consuming film digitization and CPU-intensive computations on a limited number of cases to its current status in which developed CAD approaches are evaluated rigorously on large clinically relevant databases. CAD research by medical physicists includes many aspects—collecting relevant normal and pathological cases; developing computer algorithms appropriate for the medical interpretation task including those for segmentation, feature extraction, and classifier design; developing methodology for assessing CAD performance; validating the algorithms using appropriate cases to measure performance and robustness; conducting observer studies with which to evaluate radiologists in the diagnostic task without and with the use of the computer aid; and ultimately assessing performance with a clinical trial. Medical physicists also have an important role in quantitative imaging, by validating the quantitative integrity of scanners and developing imaging techniques, and image analysis tools that extract quantitative data in a more accurate and automated fashion. As imaging systems become more complex and the need for better quantitative information from images grows, the future includes the combined research efforts from physicists working in CAD with those working on quantitative imaging systems to readily yield information on morphology, function, molecular structure, and more—from animal imaging research to clinical patient care. A historical review of CAD and a discussion of challenges for the future are presented here, along with the extension to quantitative image analysis. PMID:19175137

Anniversary Paper: History and status of CAD and quantitative image analysis: The role of Medical Physics and AAPM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giger, Maryellen L.; Chan, Heang-Ping; Boone, John

2008-12-15

The roles of physicists in medical imaging have expanded over the years, from the study of imaging systems (sources and detectors) and dose to the assessment of image quality and perception, the development of image processing techniques, and the development of image analysis methods to assist in detection and diagnosis. The latter is a natural extension of medical physicists' goals in developing imaging techniques to help physicians acquire diagnostic information and improve clinical decisions. Studies indicate that radiologists do not detect all abnormalities on images that are visible on retrospective review, and they do not always correctly characterize abnormalities thatmore » are found. Since the 1950s, the potential use of computers had been considered for analysis of radiographic abnormalities. In the mid-1980s, however, medical physicists and radiologists began major research efforts for computer-aided detection or computer-aided diagnosis (CAD), that is, using the computer output as an aid to radiologists--as opposed to a completely automatic computer interpretation--focusing initially on methods for the detection of lesions on chest radiographs and mammograms. Since then, extensive investigations of computerized image analysis for detection or diagnosis of abnormalities in a variety of 2D and 3D medical images have been conducted. The growth of CAD over the past 20 years has been tremendous--from the early days of time-consuming film digitization and CPU-intensive computations on a limited number of cases to its current status in which developed CAD approaches are evaluated rigorously on large clinically relevant databases. CAD research by medical physicists includes many aspects--collecting relevant normal and pathological cases; developing computer algorithms appropriate for the medical interpretation task including those for segmentation, feature extraction, and classifier design; developing methodology for assessing CAD performance; validating the algorithms using appropriate cases to measure performance and robustness; conducting observer studies with which to evaluate radiologists in the diagnostic task without and with the use of the computer aid; and ultimately assessing performance with a clinical trial. Medical physicists also have an important role in quantitative imaging, by validating the quantitative integrity of scanners and developing imaging techniques, and image analysis tools that extract quantitative data in a more accurate and automated fashion. As imaging systems become more complex and the need for better quantitative information from images grows, the future includes the combined research efforts from physicists working in CAD with those working on quantitative imaging systems to readily yield information on morphology, function, molecular structure, and more--from animal imaging research to clinical patient care. A historical review of CAD and a discussion of challenges for the future are presented here, along with the extension to quantitative image analysis.« less

The Global Aerosol Synthesis and Science Project (GASSP): Measurements and Modeling to Reduce Uncertainty

DOE PAGES

Reddington, C. L.; Carslaw, K. S.; Stier, P.; ...

2017-09-01

The largest uncertainty in the historical radiative forcing of climate is caused by changes in aerosol particles due to anthropogenic activity. Sophisticated aerosol microphysics processes have been included in many climate models in an effort to reduce the uncertainty. However, the models are very challenging to evaluate and constrain because they require extensive in situ measurements of the particle size distribution, number concentration, and chemical composition that are not available from global satellite observations. The Global Aerosol Synthesis and Science Project (GASSP) aims to improve the robustness of global aerosol models by combining new methodologies for quantifying model uncertainty, tomore » create an extensive global dataset of aerosol in situ microphysical and chemical measurements, and to develop new ways to assess the uncertainty associated with comparing sparse point measurements with low-resolution models. GASSP has assembled over 45,000 hours of measurements from ships and aircraft as well as data from over 350 ground stations. The measurements have been harmonized into a standardized format that is easily used by modelers and nonspecialist users. Available measurements are extensive, but they are biased to polluted regions of the Northern Hemisphere, leaving large pristine regions and many continental areas poorly sampled. The aerosol radiative forcing uncertainty can be reduced using a rigorous model–data synthesis approach. Nevertheless, our research highlights significant remaining challenges because of the difficulty of constraining many interwoven model uncertainties simultaneously. Although the physical realism of global aerosol models still needs to be improved, the uncertainty in aerosol radiative forcing will be reduced most effectively by systematically and rigorously constraining the models using extensive syntheses of measurements.« less

The Global Aerosol Synthesis and Science Project (GASSP): Measurements and Modeling to Reduce Uncertainty

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reddington, C. L.; Carslaw, K. S.; Stier, P.

The largest uncertainty in the historical radiative forcing of climate is caused by changes in aerosol particles due to anthropogenic activity. Sophisticated aerosol microphysics processes have been included in many climate models in an effort to reduce the uncertainty. However, the models are very challenging to evaluate and constrain because they require extensive in situ measurements of the particle size distribution, number concentration, and chemical composition that are not available from global satellite observations. The Global Aerosol Synthesis and Science Project (GASSP) aims to improve the robustness of global aerosol models by combining new methodologies for quantifying model uncertainty, tomore » create an extensive global dataset of aerosol in situ microphysical and chemical measurements, and to develop new ways to assess the uncertainty associated with comparing sparse point measurements with low-resolution models. GASSP has assembled over 45,000 hours of measurements from ships and aircraft as well as data from over 350 ground stations. The measurements have been harmonized into a standardized format that is easily used by modelers and nonspecialist users. Available measurements are extensive, but they are biased to polluted regions of the Northern Hemisphere, leaving large pristine regions and many continental areas poorly sampled. The aerosol radiative forcing uncertainty can be reduced using a rigorous model–data synthesis approach. Nevertheless, our research highlights significant remaining challenges because of the difficulty of constraining many interwoven model uncertainties simultaneously. Although the physical realism of global aerosol models still needs to be improved, the uncertainty in aerosol radiative forcing will be reduced most effectively by systematically and rigorously constraining the models using extensive syntheses of measurements.« less

CONTINUOUS MEASUREMENT OF PARTICLES (0.01-20.0 UM) IN AN OCCUPIED HOME, REED AND WALLACE, AAAR.

EPA Science Inventory

To better understand the contribution of outdoor and indoor sources to particle concentrations found in residential indoor air, an extensive monitoring effort has been undertaken in a three-story townhouse located in Reston, VA. Of particular interest was the determination of i...

Overview of the Gems Model of Volunteer Administration (Generate, Educate, Mobilize and Sustain)

ERIC Educational Resources Information Center

Culp, Ken, III

2012-01-01

To organize and coordinate the efforts of many volunteers, a framework for volunteer engagement is needed. The "GEMS" Model of volunteer administration was developed to assist Extension professionals and volunteer coordinators to effectively administer volunteer programs without delivering the program themselves. The GEMS Model is…

Successful Statewide Walking Program Websites

ERIC Educational Resources Information Center

Teran, Bianca Maria; Hongu, Nobuko

2012-01-01

Statewide Extension walking programs are making an effort to increase physical activity levels in America. An investigation of all 20 of these programs revealed that 14 use websites as marketing and educational tools, which could prove useful as the popularity of Internet communities continues to grow. Website usability information and an analysis…

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

40 CFR 72.94 - Units with repowering extension plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... plans. (a) Design and engineering and contract requirements. No later than January 1, 2000, the... and the permitting authority: (1) Satisfactory documentation of a preliminary design and engineering effort. (2) A binding letter agreement for the executed and binding contract (or for each in a series of...

REPORT TO THE PRESIDENT ON DOMESTIC MIGRATORY FARM LABOR.

ERIC Educational Resources Information Center

MITCHELL, JAMES P.

THE OBJECTIVES OF THE PRESIDENT'S COMMITTEE ON MIGRATORY LABOR ARE TO BRING ABOUT IMPROVED CONDITIONS FOR MIGRATORY WORKERS TO MIGRATE BY STABILIZING AGRICULTURAL EMPLOYMENT. EFFORTS HAVE BEEN DIRECTED TOWARD RESOLVING PROBLEMS OF CAMP HOUSING, SAFE TRANSPORTATION, ADEQUATE EDUCATION AND HEALTH SERVICES, EXTENSION OF LABOR LAWS TO AGRICULTURAL…

Durability of building joint sealants

Treesearch

Christopher C. White; Kar Tean Tan; Donald L. Hunston; R. Sam Williams

2009-01-01

Predicting the service life of building joint sealants exposed to service environments in less than real time has been a need of the sealant community for many decades. Despite extensive research efforts to design laboratory accelerated tests to duplicate the failure modes occurring in field exposures, little success has been achieved using conventional durability...

Tonomundo: A Public-Private Partnership in Education in Brazil

ERIC Educational Resources Information Center

Parente, Rafael

2013-01-01

The main obstacle for public-private partnerships in their efforts to improve educational quality in Brazil remains implementation -despite, in many cases, extensive support from government officials, educators, and private industry. The challenge of implementing such programs has received little attention from scholars and policy makers. This…

Child and Parent Voices on a Community-Based Prevention Program (FAST)

ERIC Educational Resources Information Center

Fearnow-Kenney, Melodie; Hill, Patricia; Gore, Nicole

2016-01-01

Families and Schools Together (FAST) is a collaborative program involving schools, families, and community-based partners in efforts to prevent substance use, juvenile delinquency, school failure, child abuse and neglect, mental health problems, and violence. Although evaluated extensively, there remains a dearth of qualitative data on child and…

Metro nature, environmental health, and economic value

Treesearch

Kathleen L. Wolf; Alicia S.T. Robbins

2015-01-01

Background: Nearly 40 years of research provides an extensive body of evidence about human health, well-being, and improved function benefits associated with experiences of nearby nature in cities.Objectives: We demonstrate the numerous opportunities for future research efforts that link metro nature, human health and well-being outcomes,...

Professional Development Needs of Mid-Career Agriculture Teachers

ERIC Educational Resources Information Center

Smalley, Scott W.; Smith, Amy R.

2017-01-01

Nationwide, agricultural education faces a shortage of teachers (National Teach Ag Campaign, 2014; Foster, Lawver, & Smith, 2016). To remedy this, both recruitment and retention efforts are necessary. While extensive research in agricultural education has focused on needs of beginning teachers, less research has focused on needs of agriculture…

Promoting Reflection in Teacher Preparation Programs: A Multilevel Model

ERIC Educational Resources Information Center

Etscheidt, Susan; Curran, Christina M.; Sawyer, Candace M.

2012-01-01

Teacher reflection has been promoted as a necessary tool for educators to sustain responsive instructional practices. A variety of approaches for integrating inquiry into teaching and reflection in practice emerged from extensive and intensive efforts to reform teacher preparation programs. Based on those conceptualizations, a three-level model of…

Social Justice and Rural Education in South Africa

ERIC Educational Resources Information Center

Hlalele, Dipane

2012-01-01

Social justice is undeniably grounded in efforts at circumventing provisions that seek to uphold ostracism and exclusionary practices which have permeated South Africa and many other societies worldwide for extensive periods of time. Vast incongruities and/or inequalities between better resourced urban communities and neglected rural areas impinge…

Functional Assessment of Alaska Peatlands in Cook Inlet Basin, Region 10 Regional Applied Research Effort (RARE)

EPA Science Inventory

Peatlands in south central Alaska are the dominant wetland class in the lowlands of the Cook Inlet Basin. Currently Alaska peatlands are extensive and largely pristine but these areas are facing increasing human development. This study focused on obtaining measures of ecologica...

Reducing Teachers' Work-Family Conflict: From Theory to Practice

ERIC Educational Resources Information Center

Cinamon, Rachel Gali; Rich, Yisrael

2005-01-01

Work-family conflict is a vocational psychology variable whose antecedents and outcomes have been extensively investigated. In contrast, less effort has been invested in creating practical programs to prevent and reduce it. This article provides the rationale and describes the framework for a comprehensive organizational program designed to ease…

Grade Expectations: Redux

ERIC Educational Resources Information Center

Miley, William M.; Gonsalves, Sonia

2004-01-01

We surveyed undergraduate students taking upper level psychology courses about their course and grade expectations as an extension of the work of Gaultney and Cann (2001) with introductory psychology students. More students believed success in a course was measured by good grades rather than by mastery of new material. They wanted effort to play a…

77 FR 43236 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-24

...). The Services take these efforts into account when making decisions on whether to list a species as... of information under the provisions of the Paperwork Reduction Act (44 U.S.C. Chapter 35). Agency.... Type of Request: Regular submission (extension of a current information collection). Number of...

Increasing Understanding of Public Problems and Policies--1990.

ERIC Educational Resources Information Center

Farm Foundation, Chicago, IL.

This collection of papers aims to improve the policy education efforts of extension workers responsible for public affairs programs. The first section, "An Evolving Public Policy Education" examines the history of public education; address current issues such as leadership models, ethics in policy formation and policy education; and…

New Science Standards: A Readiness Assessment for State Boards of Education

ERIC Educational Resources Information Center

Center on Great Teachers and Leaders, 2015

2015-01-01

State implementation of new standards (revising, adapting, and adopting new standards) is a significant undertaking. Such an effort at the state level requires extensive support, planning, and resources. Implementing new state standards also requires the support of multiple education leaders--governors, legislators, state departments of education,…

Facing NAFTA: Literacy and Work in Mexico.

ERIC Educational Resources Information Center

Flores, Gloria Hernandez; Lankshear, Colin

2000-01-01

Outlines the deep and complex challenge faced by Mexico in its quest for closer economic integration with so-called advanced economies. Discusses extensive poverty and illiteracy, and the systematic exclusion of many people from access to the very kinds of learning required by Mexico's economic project. Argues that extraordinary efforts and…

West Virginia Interpretive Guide Training: A Collaborative Effort

ERIC Educational Resources Information Center

Balcarczyk, Kelly; McKenney, Kathryn; Smaldone, Dave; Arborgast, Doug

2013-01-01

West Virginia University's Extension Service partnered with the Recreation, Parks, and Tourism Resources Program to improve guide performance in West Virginia's tourism industry. The result of this partnership is a West Virginia Interpretive Guide Training program aimed at providing low-cost, widely available training to guides throughout the…

Exploitation of American Indian Symbols: A First Amendment Analysis

ERIC Educational Resources Information Center

Hemmer, Joseph J., Jr.

2008-01-01

American Indian symbols are used extensively as logos, mascots, nicknames, and trademarks. These images identify postsecondary as well as secondary academic institutions, professional sports franchises, commercial products, and geographic locations. Over the past few decades, efforts have been directed at eliminating or at least reducing the use…

SURFACE WATER FLOW IN LANDSCAPE MODELS: 1. EVERGLADES CASE STUDY. (R824766)

EPA Science Inventory

Many landscape models require extensive computational effort using a large array of grid cells that represent the landscape. The number of spatial cells may be in the thousands and millions, while the ecological component run in each of the cells to account for landscape dynamics...

Introducing Agronomy Students to the Concepts of Indigenous and Cultural Knowledge.

ERIC Educational Resources Information Center

Schafer, John

1993-01-01

Presents a role for indigenous knowledge in extension education and research programs. Defines indigenous knowledge and then predicts efforts to utilize indigenous knowledge to facilitate the development of agriculture systems that will be agronomically, environmentally, and economically sound and enhance acceptance by practitioners because of the…

Tax Wealth in Fifty States.

ERIC Educational Resources Information Center

Halstead, D. Kent

This study presents a scheme for yearly, comparative, computation of state and local government tax capacity and effort. Figures for all states for fiscal year 1975 are presented in extensive tables. The system used is a simplified version of the Representative Tax System, which identifies tax bases, determines national average tax rates for those…

75 FR 4615 - Agency Information Collection Activities: Notice of Request for Extension of Currently Approved...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-28

... educational programs relating to the history and construction techniques of historic covered bridges... cultural tourism or enhances the history/ economic development of the community; and other benefits upon... preservation efforts; how it enhances cultural tourism or enhances the history/ economic development of the...

MECHANIZATION OF FARM OPERATIONS IN 1965.

ERIC Educational Resources Information Center

SANDERS, GROVER H.

INCREASED MECHANIZATION, MORE EXTENSIVE USE OF CHEMICALS, AND OTHER TECHNOLOGICAL DEVELOPMENTS HAVE REDUCED FARM-LABOR NEEDS AND INCREASED AGRICULTURAL PRODUCTION. COTTON, SUGAR BEETS, POTATOES, AND VEGETABLES FOR PROCESSING ARE SOME OF THE CROPS REQUIRING FEWER MAN-HOURS DUE TO NEW OR IMPROVED TECHNOLOGY. CONTINUOUS EFFORT HAS BEEN MADE TO DESIGN…

E-Assessment and Software Testing

ERIC Educational Resources Information Center

Usener, Claus A.; Majchrzak, Tim A.; Kuchen, Herbert

2012-01-01

Purpose: To overcome the high manual effort of assessments for teaching personnel, e-assessment systems are used to assess students using information systems (IS). The purpose of this paper is to propose an extension of EASy, a system for e-assessment of exercises that require higher-order cognitive skills. The latest module allows assessing…

78 FR 40513 - Division of Federal Employees' Compensation; Proposed Extension of Existing Collection; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

... DEPARTMENT OF LABOR Office of Workers' Compensation Programs Division of Federal Employees... Department of Labor, as part of its continuing effort to reduce paperwork and respondent burden, conducts a... concerning the proposed collection: Notice of Law Enforcement Officer's Injury or Occupational Disease (CA...

Rethinking the Factors of Success: Social Support and Community Coalitions

ERIC Educational Resources Information Center

Haithcox-Dennis, Melissa; DeWeese, Amanda; Goodman, Jessica

2013-01-01

Background: Coalitions are often the strategy of choice when needs are great, resources are few, and individual efforts have proven unsuccessful in addressing serious health issues. Despite the widespread use of coalitions and extensive research, no definitive list of factors predicting coalition success has been identified. One factor, social…

The Construction of Job Families Based on the Component and Overall Dimensions of the PAQ.

ERIC Educational Resources Information Center

Taylor, L. R.

1978-01-01

Seventy-six insurance company jobs were analyzed by 203 raters in an effort to assess the potential usefulness of the Position Analysis Questionnaire (PAQ) as a job analysis device to be employed in a more extensive, company-wide research program. (Editor/RK)

Teacher Mobility and Financial Incentives: A Descriptive Analysis of Denver's ProComp

ERIC Educational Resources Information Center

Fulbeck, Eleanor S.

2014-01-01

Extensive teacher mobility can undermine policy efforts to develop a high-quality workforce. In response, policymakers have increasingly championed financial incentives to retain teachers. In 2006, the Denver Public Schools adopted an alternative teacher compensation reform, the Professional Compensation System for Teachers ("ProComp").…

78 FR 40514 - Division of Federal Employees' Compensation; Proposed Extension of Existing Collection; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

... DEPARTMENT OF LABOR Office of Workers' Compensation Programs Division of Federal Employees... Department of Labor, as part of its continuing effort to reduce paperwork and respondent burden, conducts a... War Hazards Compensation Act (CA-278). A copy of the proposed information collection request can be...

XML Schema Languages: Beyond DTD.

ERIC Educational Resources Information Center

Ioannides, Demetrios

2000-01-01

Discussion of XML (extensible markup language) and the traditional DTD (document type definition) format focuses on efforts of the World Wide Web Consortium's XML schema working group to develop a schema language to replace DTD that will be capable of defining the set of constraints of any possible data resource. (Contains 14 references.) (LRW)

Regulation of Motivation: Contextual and Social Aspects

ERIC Educational Resources Information Center

Wolters, Christopher A.

2011-01-01

Background: Models of self-regulated learning have been used extensively as a way of understanding how students understand, monitor, and manage their own academic functioning. The regulation of motivation is a facet of self-regulated learning that describes students' efforts to control their own motivation or motivational processing. The…

78 FR 69643 - Proposed Information Collection; Comment Request; Generic Clearance for Customer Satisfaction...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-20

... Clearance for Customer Satisfaction Research AGENCY: U.S. Census Bureau, Commerce. ACTION: Notice. SUMMARY... requesting an extension of the generic clearance to conduct customer satisfaction research which may be in... feedback from its various customer satisfaction research efforts. Each research design is reviewed for...

Ripple Effect Mapping: A "Radiant" Way to Capture Program Impacts

ERIC Educational Resources Information Center

Kollock, Debra Hansen; Flage, Lynette; Chazdon, Scott; Paine, Nathan; Higgins, Lorie

2012-01-01

Learn more about a promising follow-up, participatory group process designed to document the results of Extension educational efforts within complex, real-life settings. The method, known as Ripple Effect Mapping, uses elements of Appreciative Inquiry, mind mapping, and qualitative data analysis to engage program participants and other community…

Developments and Changes Resulting from Writing and Thinking Assessment

ERIC Educational Resources Information Center

Flateby, Teresa

2009-01-01

This article chronicles the evolution of a large research extensive institution's General Education writing assessment efforts from an initial summative focus to a formative, improvement focus. The methods of assessment, which changed as the assessment purpose evolved, are described. As more data were collected, the measurement tool was…

OpenSearch Status

NASA Technical Reports Server (NTRS)

Newman, Doug; Silva, Sam; Mitchell, Andrew

2016-01-01

We will present an overview of our OpenSearch efforts over the past 6 months. We will discuss our Best Practices and those of CEOS concentrating on the compatibility issues between the two. We will also discuss the state of earth data OpenSearch implementations and their adherence to the standards, extensions and best practices available.

Vocational Education-Defense Establishment Collaboration: State-of-the-Practice Report.

ERIC Educational Resources Information Center

Chalupsky, Albert B.; Peirano-Dalldorf, Marie R.

This report presents a review of the historical background, progress, and problems associated with the development of collaborative efforts between vocational education and various sectors of the defense establishment. Through extensive document review, supplemented by telephone and on-site discussions with educators and employers, the benefits…

Sky online: linking amateur and professional astronomers on the world wide web

NASA Astrophysics Data System (ADS)

Fienberg, Richard Tresch

SKY Online is the World Wide Web site of Sky Publishing Corporation, publisher of Sky & Telescope magazine. Conceived mainly as an electronic extension of the company's marketing and promotion efforts, SKY Online has also proven to be a useful tool for communication between amateur and professional astronomers.

Effect of subjective knee-joint pain on the laterality of knee extension strength and gait in elderly women.

PubMed

Sugiura, Hiroki; Demura, Shinichi

2012-01-01

This study aimed to examine the effect of subjective knee-joint pain on the laterality of knee extension strength and gait in elderly women. The subjects were 144 elderly women (62-94 years old; mean age 76.2±6.0 years; ±S.D.) who were divided into the following groups: 81 persons without knee-pain (no knee-pain group), 39 persons with the subjective pain in right or left knee (single knee-pain group), and 24 persons with the subjective pain in both knees (double knee-pain group). The subjects took a knee extension strength test and a 12 m maximum effort walk test. Knee extension strength, stance time, swing time, stride length, step length and swing speed were selected as parameters. A significant laterality was found in knee extension strength only in the one knee-pain group. The laterality of gait parameters was not found in all groups. In conclusion, elderly women who can perform daily living activity independently, even though having subjective pain in either knee or laterality in knee extension strength exertion show little laterality of gait during short distance walking. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

A Retrospective Performance Assessment of the Developmental Neurotoxicity Study in Support of OECD Test Guideline 426

PubMed Central

Makris, Susan L.; Raffaele, Kathleen; Allen, Sandra; Bowers, Wayne J.; Hass, Ulla; Alleva, Enrico; Calamandrei, Gemma; Sheets, Larry; Amcoff, Patric; Delrue, Nathalie; Crofton, Kevin M.

2009-01-01

Objective We conducted a review of the history and performance of developmental neurotoxicity (DNT) testing in support of the finalization and implementation of Organisation of Economic Co-operation and Development (OECD) DNT test guideline 426 (TG 426). Information sources and analysis In this review we summarize extensive scientific efforts that form the foundation for this testing paradigm, including basic neurotoxicology research, interlaboratory collaborative studies, expert workshops, and validation studies, and we address the relevance, applicability, and use of the DNT study in risk assessment. Conclusions The OECD DNT guideline represents the best available science for assessing the potential for DNT in human health risk assessment, and data generated with this protocol are relevant and reliable for the assessment of these end points. The test methods used have been subjected to an extensive history of international validation, peer review, and evaluation, which is contained in the public record. The reproducibility, reliability, and sensitivity of these methods have been demonstrated, using a wide variety of test substances, in accordance with OECD guidance on the validation and international acceptance of new or updated test methods for hazard characterization. Multiple independent, expert scientific peer reviews affirm these conclusions. PMID:19165382

Antiangiogenic Therapy for Ischemic Retinopathies

PubMed Central

Al-Latayfeh, Motasem; Silva, Paolo S.; Sun, Jennifer K.; Aiello, Lloyd Paul

2012-01-01

Neovascularization is a common pathological process in various retinal vascular disorders including diabetic retinopathy (DR), age-related macular degeneration (AMD) and retinal vein occlusion (RVO). The development of neovascular vessels may lead to complications such as vitreous hemorrhage, fibrovascular tissue formation, and traction retinal detachments. Ultimately, irreversible vision loss may result. Various proangiogenic factors are involved in these complex processes. Different antiangiogenic drugs have been formulated in an attempt treat these vascular disorders. One factor that plays a major role in the development of retinal neovascularization is vascular endothelial growth factor (VEGF). Anti-VEGF agents are currently FDA approved for the treatment of AMD and RVO. They are also extensively used as an off-label treatment for diabetic macular edema (DME), proliferative DR, and neovascular glaucoma. However, at this time, the long-term safety of chronic VEGF inhibition has not been extensively evaluated. A large and rapidly expanding body of research on angiogenesis is being conducted at multiple centers across the globe to determine the exact contributions and interactions among a variety of angiogenic factors in an effort to determine the therapeutic potential of antiangiogenic agent in the treatment of a variety of retinal diseases. PMID:22675660

Trail degradation as influenced by environmental factors: A state-of-the-knowledge review

USGS Publications Warehouse

Leung, Y.-F.; Marion, J.L.

1996-01-01

Excerpt: Human use and misuse of land has been causing extensive degradation of the very natural resources on which we depend. National parks, wilderness and other protected natural or semi-natural areas (referred to as natural areas hereafter) represent efforts to preserve our natural heritage from further exploitation. Such areas also provide outstanding recreational, research, and educational opportunities. However, resource impacts resulting from overuse and inappropriate management increasingly threaten these protected areas and erode their natural and cultural values. Among the many forms of recreational impact, those associated with trail development and use are often a major concern of natural area managers and visitors. Such impacts impair and degrade the functions that trails serve, including (1) protecting resources by concentrating traffic on a hardened tread, (2) providing recreational opportunities along aesthetically pleasing trail routes, and (3) facilitating recreational use by providing a transportation network. The extensive distribution of trails and their degrading condition in many natural areas can have pervasive environmental effects through alteration of natural drainage patterns, erosion and deposition of soil, introduction of exotic vegetation, and increasing human-wildlife conflicts. Degraded trails also threaten the quality of visitor experiences by making travel difficult or unsafe, or by diminishing visitors ?

How mass spectrometric approaches applied to bacterial identification have revolutionized the study of human gut microbiota.

PubMed

Grégory, Dubourg; Chaudet, Hervé; Lagier, Jean-Christophe; Raoult, Didier

2018-03-01

Describing the human hut gut microbiota is one the most exciting challenges of the 21 st century. Currently, high-throughput sequencing methods are considered as the gold standard for this purpose, however, they suffer from several drawbacks, including their inability to detect minority populations. The advent of mass-spectrometric (MS) approaches to identify cultured bacteria in clinical microbiology enabled the creation of the culturomics approach, which aims to establish a comprehensive repertoire of cultured prokaryotes from human specimens using extensive culture conditions. Areas covered: This review first underlines how mass spectrometric approaches have revolutionized clinical microbiology. It then highlights the contribution of MS-based methods to culturomics studies, paying particular attention to the extension of the human gut microbiota repertoire through the discovery of new bacterial species. Expert commentary: MS-based approaches have enabled cultivation methods to be resuscitated to study the human gut microbiota and thus to fill in the blanks left by high-throughput sequencing methods in terms of culturing minority populations. Continued efforts to recover new taxa using culture methods, combined with their rapid implementation in genomic databases, would allow for an exhaustive analysis of the gut microbiota through the use of a comprehensive approach.

Heritable Endosymbionts of Drosophila

PubMed Central

Mateos, Mariana; Castrezana, Sergio J.; Nankivell, Becky J.; Estes, Anne M.; Markow, Therese A.; Moran, Nancy A.

2006-01-01

Although heritable microorganisms are increasingly recognized as widespread in insects, no systematic screens for such symbionts have been conducted in Drosophila species (the primary insect genetic models for studies of evolution, development, and innate immunity). Previous efforts screened relatively few Drosophila lineages, mainly for Wolbachia. We conducted an extensive survey of potentially heritable endosymbionts from any bacterial lineage via PCR screens of mature ovaries in 181 recently collected fly strains representing 35 species from 11 species groups. Due to our fly sampling methods, however, we are likely to have missed fly strains infected with sex ratio-distorting endosymbionts. Only Wolbachia and Spiroplasma, both widespread in insects, were confirmed as symbionts. These findings indicate that in contrast to some other insect groups, other heritable symbionts are uncommon in Drosophila species, possibly reflecting a robust innate immune response that eliminates many bacteria. A more extensive survey targeted these two symbiont types through diagnostic PCR in 1225 strains representing 225 species from 32 species groups. Of these, 19 species were infected by Wolbachia while only 3 species had Spiroplasma. Several new strains of Wolbachia and Spiroplasma were discovered, including ones divergent from any reported to date. The phylogenetic distribution of Wolbachia and Spiroplasma in Drosophila is discussed. PMID:16783009

Aberration hubs in protein interaction networks highlight actionable targets in cancer.

PubMed

Karimzadeh, Mehran; Jandaghi, Pouria; Papadakis, Andreas I; Trainor, Sebastian; Rung, Johan; Gonzàlez-Porta, Mar; Scelo, Ghislaine; Vasudev, Naveen S; Brazma, Alvis; Huang, Sidong; Banks, Rosamonde E; Lathrop, Mark; Najafabadi, Hamed S; Riazalhosseini, Yasser

2018-05-18

Despite efforts for extensive molecular characterization of cancer patients, such as the international cancer genome consortium (ICGC) and the cancer genome atlas (TCGA), the heterogeneous nature of cancer and our limited knowledge of the contextual function of proteins have complicated the identification of targetable genes. Here, we present Aberration Hub Analysis for Cancer (AbHAC) as a novel integrative approach to pinpoint aberration hubs, i.e. individual proteins that interact extensively with genes that show aberrant mutation or expression. Our analysis of the breast cancer data of the TCGA and the renal cancer data from the ICGC shows that aberration hubs are involved in relevant cancer pathways, including factors promoting cell cycle and DNA replication in basal-like breast tumors, and Src kinase and VEGF signaling in renal carcinoma. Moreover, our analysis uncovers novel functionally relevant and actionable targets, among which we have experimentally validated abnormal splicing of spleen tyrosine kinase as a key factor for cell proliferation in renal cancer. Thus, AbHAC provides an effective strategy to uncover novel disease factors that are only identifiable by examining mutational and expression data in the context of biological networks.

Orbital Transfer Vehicle (OTV) engine study. Phase A: Extension

NASA Technical Reports Server (NTRS)

Sobin, A. J.

1980-01-01

The current Phase A-Extension of the OTV engine study program aims to provide additional expander and staged combustion cycle data that will lead to design definition of the OTV engine. The proposed program effort seeks to optimize the expander cycle engine concept (consistent with identified OTV engine requirements), investigate the feasibility of kitting the staged combustion cycle engine to provide extended thrust operation, and conduct in-depth analysis of development risk, crew safety, and reliability for both cycles. Additional tasks address the costing of a 10/K thrust expander cycle engine and support of OTV systems study contractors.

Aerothermal modeling program. Phase 2, element B: Flow interaction experiment

NASA Technical Reports Server (NTRS)

Nikjooy, M.; Mongia, H. C.; Murthy, S. N. B.; Sullivan, J. P.

1987-01-01

NASA has instituted an extensive effort to improve the design process and data base for the hot section components of gas turbine engines. The purpose of element B is to establish a benchmark quality data set that consists of measurements of the interaction of circular jets with swirling flow. Such flows are typical of those that occur in the primary zone of modern annular combustion liners. Extensive computations of the swirling flows are to be compared with the measurements for the purpose of assessing the accuracy of current physical models used to predict such flows.

Aluminum as anode for energy storage and conversion: a review

NASA Astrophysics Data System (ADS)

Li, Qingfeng; Bjerrum, Niels J.

Aluminum has long attracted attention as a potential battery anode because of its high theoretical voltage and specific energy. The protective oxide layer on the aluminum surface is however detrimental to the battery performance, contributing to failure to achieve the reversible potential and causing the delayed activation of the anode. By developing aluminum alloys as anodes and solution additives to electrolytes, a variety of aluminum batteries have been extensively investigated for various applications. From molten salt and other non-aqueous electrolytes, aluminum can be electrodeposited and therefore be suitable for developing rechargable batteries. Considerable efforts have been made to develop secondary aluminum batteries of high power density. In the present paper, these research activities are reviewed, including aqueous electrolyte primary batteries, aluminum-air batteries and molten salt secondary batteries.

Dental Glass Ionomer Cements as Permanent Filling Materials? —Properties, Limitations Future Trends

PubMed Central

Lohbauer, Ulrich

2009-01-01

Glass ionomer cements (GICs) are clinically attractive dental materials that have certain unique properties that make them useful as restorative and luting materials. This includes adhesion to moist tooth structures and base metals, anticariogenic properties due to release of fluoride, thermal compatibility with tooth enamel, biocompatibility and low toxicity. The use of GICs in a mechanically loaded situation, however, has been hampered by their low mechanical performance. Poor mechanical properties, such as low fracture strength, toughness and wear, limit their extensive use in dentistry as a filling material in stress-bearing applications. In the posterior dental region, glass ionomer cements are mostly used as a temporary filling material. The requirement to strengthen those cements has lead to an ever increasing research effort into reinforcement or strengthening concepts.

Space applications of Automation, Robotics And Machine Intelligence Systems (ARAMIS). Volume 3, phase 2: Executive summary

NASA Technical Reports Server (NTRS)

Akin, D. L.; Minsky, M. L.; Thiel, E. D.; Kurtzman, C. R.

1983-01-01

The field of telepresence is defined, and overviews of those capabilities that are now available, and those that will be required to support a NASA telepresence effort are provided. Investigation of NASA's plans and goals with regard to telepresence, extensive literature search for materials relating to relevant technologies, a description of these technologies and their state of the art, and projections for advances in these technologies are included. Several space projects are examined in detail to determine what capabilities are required of a telepresence system in order to accomplish various tasks, such as servicing and assembly. The key operational and technological areas are identified, conclusions and recommendations are made for further research, and an example developmental program leading to an operational telepresence servicer is presented.

The radiologist's workflow environment: evaluation of disruptors and potential implications.

PubMed

Yu, John-Paul J; Kansagra, Akash P; Mongan, John

2014-06-01

Workflow interruptions in the health care delivery environment are a major contributor to medical errors and have been extensively studied within numerous hospital settings, including the nursing environment and the operating room, along with their effects on physician workflow. Less understood, though, is the role of interruptions in other highly specialized clinical domains and subspecialty services, such as diagnostic radiology. The workflow of the on-call radiologist, in particular, is especially susceptible to disruption by telephone calls and other modes of physician-to-physician communication. Herein, the authors describe their initial efforts to quantify the degree of interruption experienced by on-call radiologists and examine its potential implications in patient safety and overall clinical care. Copyright © 2014 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Surface-functionalized nanoparticles for biosensing and imaging-guided therapeutics

NASA Astrophysics Data System (ADS)

Jiang, Shan; Win, Khin Yin; Liu, Shuhua; Teng, Choon Peng; Zheng, Yuangang; Han, Ming-Yong

2013-03-01

In this article, the very recent progress of various functional inorganic nanomaterials is reviewed including their unique properties, surface functionalization strategies, and applications in biosensing and imaging-guided therapeutics. The proper surface functionalization renders them with stability, biocompatibility and functionality in physiological environments, and further enables their targeted use in bioapplications after bioconjugation via selective and specific recognition. The surface-functionalized nanoprobes using the most actively studied nanoparticles (i.e., gold nanoparticles, quantum dots, upconversion nanoparticles, and magnetic nanoparticles) make them an excellent platform for a wide range of bioapplications. With more efforts in recent years, they have been widely developed as labeling probes to detect various biological species such as proteins, nucleic acids and ions, and extensively employed as imaging probes to guide therapeutics such as drug/gene delivery and photothermal/photodynamic therapy.

Disequilibrium condensation environments in space - A frontier in thermodynamics

NASA Technical Reports Server (NTRS)

De, B. R.

1979-01-01

The thermal-disequilibrium aspect of the problem of dust-particle formation from a gas phase in an open space environment is discussed in an effort to draw attention to the space condensation environment as an interesting arena for application and extension of the ideas and formalisms of nonequilibrium thermodynamics. It is shown that quasi-steady states with a disequilibrium between the gas-phase kinetic temperature and the condensed-phase internal temperature appear to be the norm of condensation environments in space. Consideration of the case of condensation onto a bulk condensed phase indicates that these quasi-steady states may constitute Prigogine dissipative structures. It is suggested that a proper study of the process of condensation in a space environment should include any effects arising from thermal disequilibrium.

Overview: Parity Violation and Fundamental Symmetries

NASA Astrophysics Data System (ADS)

Carlini, Roger

2017-09-01

The fields of nuclear and particle physics have undertaken extensive programs of research to search for evidence of new phenomena via the precision measurement of observables that are well predicted within the standard model of electroweak interaction. It is already known that the standard model is incomplete as it does not include gravity and dark matter/energy and therefore likely the low energy approximation of a more complex theory. This talk will be an overview of the motivation, experimental methods and status of some of these efforts (past and future) related to precision in-direct searches that are complementary to the direct searches underway at the Large Hadron Collider. This abstract is for the invited talk associated with the Mini-symposium titled ``Electro-weak Physics and Fundamental Symmetries'' organized by Julie Roche.

Tank vapor mitigation requirements for Hanford Tank Farms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rakestraw, L.D.

1994-11-15

Westinghouse Hanford Company has contracted Los Alamos Technical Associates to listing of vapors and aerosols that are or may be emitted from the High Level Waste (HLW) tanks at Hanford. Mitigation requirements under Federal and State law, as well as DOE Orders, are included in the listing. The lists will be used to support permitting activities relative to tank farm ventilation system up-grades. This task is designated Task 108 under MJB-SWV-312057 and is an extension of efforts begun under Task 53 of Purchase Order MPB-SVV-03291 5 for Mechanical Engineering Support. The results of that task, which covered only thirty-nine tanks,more » are repeated here to provide a single source document for vapor mitigation requirements for all 177 HLW tanks.« less

Some issues and subtleties in numerical simulation of X-ray FEL's

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fawley, William M.

Part of the overall design effort for x-ray FEL's such as the LCLS and TESLA projects has involved extensive use of particle simulation codes to predict their output performance and underlying sensitivity to various input parameters (e.g. electron beam emittance). This paper discusses some of the numerical issues that must be addressed by simulation codes in this regime. We first give a brief overview of the standard approximations and simulation methods adopted by time-dependent(i.e. polychromatic) codes such as GINGER, GENESIS, and FAST3D, including the effects of temporal discretization and the resultant limited spectral bandpass,and then discuss the accuracies and inaccuraciesmore » of these codes in predicting incoherent spontaneous emission (i.e. the extremely low gain regime).« less

Sampling design for long-term regional trends in marine rocky intertidal communities

USGS Publications Warehouse

Irvine, Gail V.; Shelley, Alice

2013-01-01

Probability-based designs reduce bias and allow inference of results to the pool of sites from which they were chosen. We developed and tested probability-based designs for monitoring marine rocky intertidal assemblages at Glacier Bay National Park and Preserve (GLBA), Alaska. A multilevel design was used that varied in scale and inference. The levels included aerial surveys, extensive sampling of 25 sites, and more intensive sampling of 6 sites. Aerial surveys of a subset of intertidal habitat indicated that the original target habitat of bedrock-dominated sites with slope ≤30° was rare. This unexpected finding illustrated one value of probability-based surveys and led to a shift in the target habitat type to include steeper, more mixed rocky habitat. Subsequently, we evaluated the statistical power of different sampling methods and sampling strategies to detect changes in the abundances of the predominant sessile intertidal taxa: barnacles Balanomorpha, the mussel Mytilus trossulus, and the rockweed Fucus distichus subsp. evanescens. There was greatest power to detect trends in Mytilus and lesser power for barnacles and Fucus. Because of its greater power, the extensive, coarse-grained sampling scheme was adopted in subsequent years over the intensive, fine-grained scheme. The sampling attributes that had the largest effects on power included sampling of “vertical” line transects (vs. horizontal line transects or quadrats) and increasing the number of sites. We also evaluated the power of several management-set parameters. Given equal sampling effort, sampling more sites fewer times had greater power. The information gained through intertidal monitoring is likely to be useful in assessing changes due to climate, including ocean acidification; invasive species; trampling effects; and oil spills.

Assessing risks and preventing disease from environmental chemicals.

PubMed

Dunnette, D A

1989-01-01

In the last 25 years there has been considerable concern expressed about the extent to which chemical agents in the ambient and work environments are contributing to the causation of disease. This concern is a logical extension of our increased knowledge of the real and potential effects of environmental chemicals and the methodological difficulties in applying new knowledge that could help prevent environmentally induced disease. Chemical risk assessment offers an approach to estimating risks and involves consideration of relevant information including identification of chemical hazards, evaluation of the dose-response relationship, estimation of exposure and finally, risk characterization. Particularly significant uncertainties which are inherent in use of this and other risk models include animal-human and low dose-high dose extrapolation and estimation of exposure. Community public health risks from exposure to environmental chemicals appear to be small relative to other public health risks based on information related to cancer trends, dietary intake of synthetic chemicals, assessment data on substances such as DDT and "dioxin," public health effects of hazardous waste sites and contextual considerations. Because of inherent uncertainty in the chemical risk assessment process, however, we need to apply what methods are available in our efforts to prevent disease induced by environmental chemicals. There are a number of societal strategies which can contribute to overall reduction of risk from environmental chemicals. These include acquisition of information on environmental risk including toxicity, intensity and extensity of exposure, biological monitoring, disease surveillance, improvement in epidemiological methods, control of environmental chemical exposures, and dissemination of hazardous chemical information. Responsible environmental risk communication and information transfer appear to be among the most important of the available strategies for preventing disease induced by chemicals in the environment.

Direct Coaptation of the Phrenic Nerve With the Posterior Division of the Lower Trunk to Restore Finger and Elbow Extension Function in Patients With Total Brachial Plexus Injuries.

PubMed

Wang, Shu-feng; Li, Peng-cheng; Xue, Yun-hao; Zou, Ji-yao; Li, Wen-jun; Li, Yucheng

2016-02-01

To overcome the mismatch in nerve sizes in phrenic nerve transfer to the radial nerve for elbow and finger extension reanimation for patients with total brachial plexus injuries (TBPI), a selective neurotization procedure was designed. To investigate the long-term results of phrenic nerve transfer to the posterior division of the lower trunk with direct coaptation in restoring elbow and finger extension after TBPI. Phrenic nerve was transferred to and directly coapted with the posterior division of the lower trunk in 27 patients with TBPI. Seven patients were <18 years old (adolescent group), and the remaining 20 patients ≥18 years (adult group). Postoperative mean follow-up period was 54 ± 9 months (range, 48-85 months). The motor function attained M3 or greater in 81.5% of patients for elbow extension and in 48% of patients for finger extension. The percentage of patients who regained M3 or greater muscle power of finger extension in the adolescent group and the adult group was 71.4%, and 40%, respectively. Meanwhile, 85.7% in the adolescent group and 80% in the adult group achieved M3 or greater muscle power of elbow extension. There were no significant differences between the 2 groups. The elbow extension and finger extension were synchronous contractions and did not become independent of respiratory effort. This procedure simultaneously and effectively restores the function of elbow and finger extension in patients after TBPI. However, the patients could not do elbow and finger extension separately.