Science.gov

Sample records for einsteinium 248

  1. Einsteinium

    NASA Astrophysics Data System (ADS)

    Haire, Richard G.

    The discovery of einsteinium, element 99, came about during the analyses of nuclear products produced in and then recovered from test debris following a thermonuclear explosion (weapon test device, ‘Mike', November 1952) at Eniwetok Atoll in the Pacific Ocean. The uranium present in this device was subjected to a very intense neutron flux (integrated fluence of about 1024neutrons) in an extremely short time frame (few nanoseconds), which allowed a large number of multiple neutron captures with a minimal degree of decay of the products formed. Nuclei were formed with usually high neutron/proton ratios (very ‘heavy' uranium isotopes), which then rapidly beta-decayed into new, transuranium isotopes through element 100. Scientists from several U.S. Government laboratories separated and analyzed extensively the debris samplings in the following weeks. From these investigations came the discovery and identification of einsteinium and fermium. The first element was named in honor of Albert Einstein, and assigned the symbol, E (later changed to the current symbol, Es). Additional details and discussions about the discovery of this element and the scientists involved are given in several references (Thompson et al., 1954; Ghiorso et al., 1955; Fields et al., 1956; Hyde et al., 1964; Seaborg and Loveland, 1990).

  2. Ion-exchange chromatographic separation of einsteinium from irradiated californium targets

    SciTech Connect

    Elesin, A.A.; Nikolaev, V.M.; Shalimov, V.V.; Popov, Yu.S.; Kovantsev, V.N.; Tselishchev, I.V.; Filimonov, V.T.; Mishenev, V.B.; Yadovin, A.A.; Golosovskii, L.S.; Chetverikov, A.P.

    1987-07-01

    Einsteinium was obtained by preparing two experimental californium targets and subjecting them to neutron irradiation in a high-flux reactor. The einsteinium was separated from the bombarded targets on a column packed with KU-2U sulfonated cation-exchange resin (20-50 ..mu..m) and eluted at room temperature with an ammonium ..cap alpha..-hydroxyisobutyrate solution. Three successive separation cycles removed californium to produce einsteinium in 68% yield with a decontamination factor of 5.3 x 10/sup 6/. About 20% of the einsteinium was used up by analysis and 11% remained in intermediate fractions. The method developed yielded pure einsteinium with little fission products present. The contribution of the fission products to the total einsteinium gamma-irradiation dose rate was no greater than 81%, due primarily to the radioisotope terbium-160.

  3. Electron-capture delayed fission properties of neutron-deficient einsteinium nuclei

    SciTech Connect

    Shaughnessy, Dawn A.

    2000-01-01

    Electron-capture delayed fission (ECDF) properties of neutron-deficient einsteinium isotopes were investigated using a combination of chemical separations and on-line radiation detection methods. 242Es was produced via the 233U(14N,5n)242Es reaction at a beam energy of 87 MeV (on target) in the lab system, and was found to decay with a half-life of 11 ± 3 seconds. The ECDF of 242Es showed a highly asymmetric mass distribution with an average pre-neutron emission total kinetic energy (TKE) of 183 ± 18 MeV. The probability of delayed fission (PDF) was measured to be 0.006 ± 0.002. In conjunction with this experiment, the excitation functions of the 233U(14N,xn)247-xEs and 233U(15N,xn)248-xEs reactions were measured for 243Es, 244Es and 245Es at projectile energies between 80 MeV and 100 MeV.

  4. Chemical Properties of Elements 99 and 100 [Einsteinium and Fermium

    DOE R&D Accomplishments Database

    Seaborg, G. T.; Thompson, S. G.; Harvey, B. G.; Choppin, G. R.

    1954-07-23

    A description of some of the chemical properties and of the methods used in the separations of elements 99 [Einsteinium] and 100 [Fermium] are given. The new elements exhibit the properties expected for the tenth and eleventh actinide elements. Attempts to produce an oxidation state greater than III of element 99 have been unsuccessful. In normal aqueous media only the III state of element 100 appears to exist. The relative spacings of the elution peaks of the new elements in some separations with ion exchange resin columns are the same as the relative spacings of the homologous lanthanide elements. The results of experiments involving cation exchange resins with very concentrated hydrochloric acid eluant show that the new elements, like the earlier actinides, are more strongly complexed than the lanthanides. The new elements also exist partially as anions in concentrated hydrochloric acid, as do earlier actinide elements, and they may be partially separated from each other by means of ion exchange resins. With some eluants interesting reversals of elution positions are observed in the region Bk-Cf-99-100, indicating complex ion formation involving unusual factors.

  5. Hyperfine field of einsteinium in iron and nuclear magnetic moment of {sup 254}Es

    SciTech Connect

    Severijns, N.; Kraev, I. S.; Phalet, T.; Tandecki, M.; Traykov, E.; Gorp, S. Van; Wauters, F.; Belyaev, A. A.; Lukhanin, A. A.; Noga, V. I.; Erzinkyan, A. L.; Parfenova, V. P.; Eversheim, P.-D.; Herzog, P.; Tramm, C.; Filimonov, V. T.; Toporov, Yu. G.; Zotov, E.; Golovko, V. V.; Gurevich, G. M.

    2009-06-15

    The angular distributions of {gamma} rays and {alpha} particles from oriented {sup 250}Bk, {sup 253,254}Es, and {sup 255}Fm nuclei were investigated to extract hyperfine interaction information for these actinide impurities in an iron host lattice. The hyperfine field of einsteinium in iron was found to be |B{sub hf}(EsFe{sub lowbar|})=396(32) T. With this value the magnetic moment of {sup 254}Es was then determined as |{mu}|=4.35(41) {mu}{sub N}.

  6. 17 CFR 248.103-248.119 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false 248.103-248.119 Section 248.103-248.119 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §§ 248.103-248.119...

  7. 17 CFR 248.103-248.119 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false 248.103-248.119 Section 248.103-248.119 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §§ 248.103-248.119...

  8. 17 CFR 248.103-248.119 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false 248.103-248.119 Section 248.103-248.119 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §§ 248.103-248.119...

  9. 17 CFR 248.103-248.119 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false 248.103-248.119 Section 248.103-248.119 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §§ 248.103-248.119...

  10. 17 CFR 248.103-248.119 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false 248.103-248.119 Section 248.103-248.119 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §§ 248.103-248.119...

  11. 17 CFR 248.31-248.100 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false 248.31-248.100 Section 248.31-248.100 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding...

  12. 17 CFR 248.19-248.29 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false 248.19-248.29 Section 248.19-248.29 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding...

  13. 7 CFR 248.18 - Audits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Audits. 248.18 Section 248.18 Agriculture Regulations... Agencies § 248.18 Audits. (a) Federal access to information. The Secretary, the Comptroller General of the... the purpose of making surveys, audits, examinations, excerpts, and transcripts. (b) State agency...

  14. 7 CFR 248.7 - Nondiscrimination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nondiscrimination. 248.7 Section 248.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.7...

  15. 7 CFR 248.24 - Other provisions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Other provisions. 248.24 Section 248.24 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.24...

  16. 7 CFR 248.15 - Closeout procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Closeout procedures. 248.15 Section 248.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.15...

  17. 7 CFR 248.13 - FMNP income.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false FMNP income. 248.13 Section 248.13 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.13...

  18. 7 CFR 248.6 - Recipient eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Recipient eligibility. 248.6 Section 248.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.6...

  19. 7 CFR 248.25 - FMNP information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false FMNP information. 248.25 Section 248.25 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.25...

  20. 40 CFR 1065.248 - Gas divider.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Gas divider. 1065.248 Section 1065.248... PROCEDURES Measurement Instruments Flow-Related Measurements § 1065.248 Gas divider. (a) Application. You may use a gas divider to blend calibration gases. (b) Component requirements. Use a gas divider that...

  1. 7 CFR 248.18 - Audits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Audits. 248.18 Section 248.18 Agriculture Regulations... Agencies § 248.18 Audits. (a) Federal access to information. The Secretary, the Comptroller General of the... the purpose of making surveys, audits, examinations, excerpts, and transcripts. (b) State...

  2. 17 CFR 248.102 - Examples.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Examples. 248.102 Section 248.102 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.102 Examples. The examples in...

  3. 17 CFR 248.120 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Definitions. 248.120 Section 248.120 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.120 Definitions. As used...

  4. 17 CFR 248.120 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Definitions. 248.120 Section 248.120 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing § 248.120 Definitions....

  5. 17 CFR 248.120 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Definitions. 248.120 Section 248.120 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.120 Definitions. As used...

  6. 17 CFR 248.102 - Examples.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Examples. 248.102 Section 248.102 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.102 Examples. The examples in...

  7. 17 CFR 248.102 - Examples.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Examples. 248.102 Section 248.102 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing § 248.102 Examples. The...

  8. 17 CFR 248.102 - Examples.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Examples. 248.102 Section 248.102 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.102 Examples. The examples in...

  9. 17 CFR 248.102 - Examples.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Examples. 248.102 Section 248.102 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.102 Examples. The examples in...

  10. 7 CFR 946.248 - Assessment rate.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Assessment rate. 946.248 Section 946.248 Agriculture... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN WASHINGTON Rules and Regulations Modification of Inspection Requirements § 946.248 Assessment rate. On and after...

  11. 7 CFR 946.248 - Assessment rate.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Assessment rate. 946.248 Section 946.248 Agriculture... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN WASHINGTON Rules and Regulations Modification of Inspection Requirements § 946.248 Assessment rate. On and after...

  12. 7 CFR 248.19 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Investigations. 248.19 Section 248.19 Agriculture... Agencies § 248.19 Investigations. (a) Authority. The Department may make an investigation of any allegation of noncompliance with this part and FNS guidelines and instructions. The investigation may...

  13. 7 CFR 248.19 - Investigations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Investigations. 248.19 Section 248.19 Agriculture... Agencies § 248.19 Investigations. (a) Authority. The Department may make an investigation of any allegation of noncompliance with this part and FNS guidelines and instructions. The investigation may...

  14. 7 CFR 248.19 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Investigations. 248.19 Section 248.19 Agriculture... Agencies § 248.19 Investigations. (a) Authority. The Department may make an investigation of any allegation of noncompliance with this part and FNS guidelines and instructions. The investigation may...

  15. 7 CFR 248.19 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Investigations. 248.19 Section 248.19 Agriculture... Agencies § 248.19 Investigations. (a) Authority. The Department may make an investigation of any allegation of noncompliance with this part and FNS guidelines and instructions. The investigation may...

  16. 7 CFR 248.19 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Investigations. 248.19 Section 248.19 Agriculture... Agencies § 248.19 Investigations. (a) Authority. The Department may make an investigation of any allegation of noncompliance with this part and FNS guidelines and instructions. The investigation may...

  17. 7 CFR 248.13 - FMNP income.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false FMNP income. 248.13 Section 248.13 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.13...

  18. 7 CFR 248.15 - Closeout procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Closeout procedures. 248.15 Section 248.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.15...

  19. 7 CFR 248.7 - Nondiscrimination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Nondiscrimination. 248.7 Section 248.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.7...

  20. 7 CFR 248.6 - Recipient eligibility.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Recipient eligibility. 248.6 Section 248.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.6...

  1. 7 CFR 248.6 - Recipient eligibility.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Recipient eligibility. 248.6 Section 248.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.6...

  2. 7 CFR 248.15 - Closeout procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Closeout procedures. 248.15 Section 248.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.15...

  3. 7 CFR 248.7 - Nondiscrimination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Nondiscrimination. 248.7 Section 248.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.7...

  4. 7 CFR 248.9 - Nutrition education.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Nutrition education. 248.9 Section 248.9 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Benefits § 248.9...

  5. 7 CFR 248.13 - FMNP income.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false FMNP income. 248.13 Section 248.13 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.13...

  6. 7 CFR 248.24 - Other provisions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Other provisions. 248.24 Section 248.24 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.24...

  7. 7 CFR 248.13 - FMNP income.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false FMNP income. 248.13 Section 248.13 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.13...

  8. 7 CFR 248.6 - Recipient eligibility.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Recipient eligibility. 248.6 Section 248.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.6...

  9. 7 CFR 248.9 - Nutrition education.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Nutrition education. 248.9 Section 248.9 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Benefits § 248.9...

  10. 7 CFR 248.13 - FMNP income.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false FMNP income. 248.13 Section 248.13 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.13...

  11. 7 CFR 248.7 - Nondiscrimination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Nondiscrimination. 248.7 Section 248.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.7...

  12. 7 CFR 248.15 - Closeout procedures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Closeout procedures. 248.15 Section 248.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.15...

  13. 7 CFR 248.9 - Nutrition education.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Nutrition education. 248.9 Section 248.9 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Benefits § 248.9...

  14. 7 CFR 248.7 - Nondiscrimination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Nondiscrimination. 248.7 Section 248.7 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.7...

  15. 7 CFR 248.6 - Recipient eligibility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Recipient eligibility. 248.6 Section 248.6 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Eligibility § 248.6...

  16. 7 CFR 248.15 - Closeout procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Closeout procedures. 248.15 Section 248.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.15...

  17. 7 CFR 248.9 - Nutrition education.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Nutrition education. 248.9 Section 248.9 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Benefits § 248.9...

  18. 40 CFR 98.248 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... GREENHOUSE GAS REPORTING Petrochemical Production § 98.248 Definitions. Except as specified in this section... onsite. Product does not include process vent emissions, fugitive emissions, or wastewater. ...

  19. 7 CFR 248.25 - FMNP information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false FMNP information. 248.25 Section 248.25 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions §...

  20. 7 CFR 248.25 - FMNP information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false FMNP information. 248.25 Section 248.25 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions §...

  1. 7 CFR 248.25 - FMNP information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false FMNP information. 248.25 Section 248.25 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions §...

  2. 7 CFR 248.25 - FMNP information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false FMNP information. 248.25 Section 248.25 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions §...

  3. 40 CFR 1065.248 - Gas divider.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Gas divider. 1065.248 Section 1065.248 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING... testing. You may use critical-flow gas dividers, capillary-tube gas dividers, or thermal-mass-meter...

  4. 40 CFR 1065.248 - Gas divider.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Gas divider. 1065.248 Section 1065.248 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING... testing. You may use critical-flow gas dividers, capillary-tube gas dividers, or thermal-mass-meter...

  5. 40 CFR 1065.248 - Gas divider.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Gas divider. 1065.248 Section 1065.248 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING... testing. You may use critical-flow gas dividers, capillary-tube gas dividers, or thermal-mass-meter...

  6. 40 CFR 1065.248 - Gas divider.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Gas divider. 1065.248 Section 1065.248 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING... testing. You may use critical-flow gas dividers, capillary-tube gas dividers, or thermal-mass-meter...

  7. 24 CFR 248.301 - Initial application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... manner by which the State housing program provides mortgage assistance or subsidy to private mortgagors... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Initial application. 248.301 Section 248.301 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  8. 24 CFR 248.301 - Initial application.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... manner by which the State housing program provides mortgage assistance or subsidy to private mortgagors... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Initial application. 248.301 Section 248.301 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  9. 24 CFR 248.301 - Initial application.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... manner by which the State housing program provides mortgage assistance or subsidy to private mortgagors... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Initial application. 248.301 Section 248.301 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  10. 24 CFR 248.301 - Initial application.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... manner by which the State housing program provides mortgage assistance or subsidy to private mortgagors... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Initial application. 248.301 Section 248.301 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  11. 7 CFR 248.12 - FMNP costs.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.12... associated with the provision of nutrition education which meets the requirements of § 248.9 of this part. (2...

  12. 7 CFR 248.9 - Nutrition education.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nutrition education. 248.9 Section 248.9 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient Benefits §...

  13. 24 CFR 248.147 - Housing standards.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Housing standards. 248.147 Section 248.147 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND...

  14. 24 CFR 248.147 - Housing standards.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Housing standards. 248.147 Section 248.147 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND...

  15. 24 CFR 248.147 - Housing standards.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Housing standards. 248.147 Section 248.147 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND...

  16. 24 CFR 248.147 - Housing standards.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Housing standards. 248.147 Section 248.147 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND...

  17. 24 CFR 248.147 - Housing standards.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Housing standards. 248.147 Section 248.147 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND...

  18. 7 CFR 248.12 - FMNP costs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.12... associated with the provision of nutrition education which meets the requirements of § 248.9 of this part. (2...

  19. 7 CFR 248.12 - FMNP costs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.12... associated with the provision of nutrition education which meets the requirements of § 248.9 of this part. (2...

  20. 7 CFR 248.12 - FMNP costs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.12... associated with the provision of nutrition education which meets the requirements of § 248.9 of this part. (2...

  1. 7 CFR 248.12 - FMNP costs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.12... associated with the provision of nutrition education which meets the requirements of § 248.9 of this part. (2...

  2. 24 CFR 248.401 - Purposes.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... INCOME HOUSING MORTGAGES Technical Assistance and Capacity Building § 248.401 Purposes. The purposes of... their housing; (b) To promote the ability of community-based nonprofit organizations and...

  3. 40 CFR 98.248 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Petrochemical Production § 98.248 Definitions. Except as specified in this section... onsite. Product does not include process vent emissions, fugitive emissions, or wastewater. ...

  4. CD248 — EDRN Public Portal

    Cancer.gov

    CD248 is a 165-kD cell surface glycoprotein expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. There is also evidence that CD248 is expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing, in vascular endothelial cells of malignant tumors but not in normal blood vessels, and in stromal fibroblasts.

  5. 14 CFR 248.2 - Filing of audit reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Filing of audit reports. 248.2 Section 248...) ECONOMIC REGULATIONS SUBMISSION OF AUDIT REPORTS § 248.2 Filing of audit reports. (a) Whenever any air carrier subject to § 248.1 shall have caused an annual audit of its books, records, and accounts to...

  6. Nuclear Data Sheets for A = 248

    SciTech Connect

    Martin, M.J.

    2014-11-15

    Detailed level schemes, decay schemes, and the experimental data on which they are based are presented for all nuclei with mass number A=248. The experimental reaction and decay data are evaluated; inconsistencies and discrepancies are noted; and adopted values are given for various level properties (including spin and parity, halflife, and configuration), γ properties (including energy, intensity, and multipole character) and α properties (including energy, intensity, and hindrance factor). This evaluation replaces the A=248 evaluation published by A. Akovali in Nuclear Data Sheets 87, 249 (1999)

  7. 24 CFR 248.133 - Second notice of intent.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Second notice of intent. 248.133... Preservation and Resident Homeownership Act of 1990 § 248.133 Second notice of intent. (a) Filing. A second... Commissioner in § 248.131, elect to transfer the project under §§ 248.157 or 248.161. (b) Timeliness. A...

  8. 24 CFR 248.133 - Second notice of intent.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Second notice of intent. 248.133... Preservation and Resident Homeownership Act of 1990 § 248.133 Second notice of intent. (a) Filing. A second... Commissioner in § 248.131, elect to transfer the project under §§ 248.157 or 248.161. (b) Timeliness. A...

  9. 24 CFR 248.133 - Second notice of intent.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Second notice of intent. 248.133... Preservation and Resident Homeownership Act of 1990 § 248.133 Second notice of intent. (a) Filing. A second... Commissioner in § 248.131, elect to transfer the project under §§ 248.157 or 248.161. (b) Timeliness. A...

  10. 24 CFR 248.133 - Second notice of intent.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Second notice of intent. 248.133... Preservation and Resident Homeownership Act of 1990 § 248.133 Second notice of intent. (a) Filing. A second... Commissioner in § 248.131, elect to transfer the project under §§ 248.157 or 248.161. (b) Timeliness. A...

  11. 24 CFR 248.133 - Second notice of intent.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Second notice of intent. 248.133... Preservation and Resident Homeownership Act of 1990 § 248.133 Second notice of intent. (a) Filing. A second... Commissioner in § 248.131, elect to transfer the project under §§ 248.157 or 248.161. (b) Timeliness. A...

  12. 21 CFR 558.248 - Erythromycin thiocyanate.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS Specific New Animal Drugs for Use in Animal Feeds § 558.248 Erythromycin thiocyanate. (a) Approvals. Type A medicated...

  13. 7 CFR 248.3 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.3 Administration. (a... nutrition education in coordination with the WIC Program, coupon and market management, fiscal reporting...

  14. 7 CFR 248.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.2 Definitions. For..., nutrition education, outreach, eligibility determination, and developing, printing, and distributing coupons...

  15. 7 CFR 248.4 - State Plan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility § 248.4... designated administering State agency and the WIC State agency, if different, for services such as nutrition...

  16. 24 CFR 248.420 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OF LOW INCOME HOUSING MORTGAGES Technical Assistance and Capacity Building § 248.420 Definitions. Community-based nonprofit housing developer means a nonprofit community development corporation that: (1... community in which the project is located; (4) Is organized at the neighborhood, city, county, or...

  17. 25 CFR 248.6 - Structures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... § 248.6 Structures. Dwellings, camping facilities, and other structures such as fish drying facilities... treaty fishing and related activities. Sites must be used in a manner that conforms to the health... local laws, to the health, sanitation, and safety recommendations of the U.S. Public Health Service....

  18. 25 CFR 248.6 - Structures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... § 248.6 Structures. Dwellings, camping facilities, and other structures such as fish drying facilities... treaty fishing and related activities. Sites must be used in a manner that conforms to the health... local laws, to the health, sanitation, and safety recommendations of the U.S. Public Health Service....

  19. 25 CFR 248.6 - Structures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... § 248.6 Structures. Dwellings, camping facilities, and other structures such as fish drying facilities... treaty fishing and related activities. Sites must be used in a manner that conforms to the health... local laws, to the health, sanitation, and safety recommendations of the U.S. Public Health Service....

  20. 25 CFR 248.6 - Structures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... § 248.6 Structures. Dwellings, camping facilities, and other structures such as fish drying facilities... treaty fishing and related activities. Sites must be used in a manner that conforms to the health... local laws, to the health, sanitation, and safety recommendations of the U.S. Public Health Service....

  1. 25 CFR 248.6 - Structures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... § 248.6 Structures. Dwellings, camping facilities, and other structures such as fish drying facilities... treaty fishing and related activities. Sites must be used in a manner that conforms to the health... local laws, to the health, sanitation, and safety recommendations of the U.S. Public Health Service....

  2. 24 CFR 248.101 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...; however, the State or local government may not have the right to appoint more than one-third of the... general local or State government in which a project is located pursuant to title II of the Cranston... homeownership program established in § 248.173, any State or unit of general local government that has been so...

  3. 46 CFR 170.248 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ALL INSPECTED VESSELS Watertight Bulkhead Doors § 170.248 Applicability. (a) Except as provided in paragraphs (b) through (d) of this section, this subpart applies to vessels with watertight doors in... subchapter. (b) A watertight door on a MODU must comply with § 174.100 of this subchapter. (c) A watertight...

  4. 31 CFR 248.1 - Introductory.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FOREIGN COUNTRIES OR UNITED STATES TERRITORIES OR POSSESSIONS § 248.1 Introductory. This part governs the issuance of substitutes for checks of the United States drawn on United States dollar or foreign currency accounts, maintained with designated depositaries in foreign countries or territories or possessions of...

  5. 7 CFR 248.24 - Other provisions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.24.... Russell National School Lunch Act and the Child Nutrition Act of 1966 (42 U.S.C. 1786). ...

  6. 7 CFR 248.24 - Other provisions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.24.... Russell National School Lunch Act and the Child Nutrition Act of 1966 (42 U.S.C. 1786). ...

  7. 7 CFR 248.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.2 Definitions. For..., nutrition education, outreach, eligibility determination, and developing, printing, and distributing coupons...

  8. 7 CFR 248.4 - State Plan.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility § 248.4... designated administering State agency and the WIC State agency, if different, for services such as nutrition...

  9. 7 CFR 248.4 - State Plan.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility § 248.4... designated administering State agency and the WIC State agency, if different, for services such as nutrition...

  10. 7 CFR 248.3 - Administration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.3 Administration. (a... nutrition education in coordination with the WIC Program, coupon and market management, fiscal reporting...

  11. 7 CFR 248.24 - Other provisions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.24.... Russell National School Lunch Act and the Child Nutrition Act of 1966 (42 U.S.C. 1786). ...

  12. 7 CFR 248.4 - State Plan.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility § 248.4... designated administering State agency and the WIC State agency, if different, for services such as nutrition...

  13. 7 CFR 248.3 - Administration.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.3 Administration. (a... nutrition education in coordination with the WIC Program, coupon and market management, fiscal reporting...

  14. 7 CFR 248.3 - Administration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.3 Administration. (a... nutrition education in coordination with the WIC Program, coupon and market management, fiscal reporting...

  15. 7 CFR 248.3 - Administration.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.3 Administration. (a... nutrition education in coordination with the WIC Program, coupon and market management, fiscal reporting...

  16. 7 CFR 248.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.2 Definitions. For..., nutrition education, outreach, eligibility determination, and developing, printing, and distributing coupons...

  17. 7 CFR 248.4 - State Plan.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility § 248.4... designated administering State agency and the WIC State agency, if different, for services such as nutrition...

  18. 7 CFR 248.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.2 Definitions. For..., nutrition education, outreach, eligibility determination, and developing, printing, and distributing coupons...

  19. 7 CFR 248.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.2 Definitions. For..., nutrition education, outreach, eligibility determination, and developing, printing, and distributing coupons...

  20. 7 CFR 58.248 - Nonfat dry milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Nonfat dry milk. 58.248 Section 58.248 Agriculture... Products Bearing Usda Official Identification § 58.248 Nonfat dry milk. (a) Nonfat dry milk in commercial....S. Standard Grade. (b) Regular nonfat dry milk in consumer size packages which bears an...

  1. 7 CFR 248.10 - Coupon and market management.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Coupon and market management. 248.10 Section 248.10... AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.10 Coupon and market management. (a) General. This section sets forth State agency...

  2. 7 CFR 248.10 - Coupon and market management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Coupon and market management. 248.10 Section 248.10... AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions § 248.10 Coupon and market management. (a) General. This section sets forth State agency...

  3. 7 CFR 248.26 - OMB control number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false OMB control number. 248.26 Section 248.26 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.26...

  4. 10 CFR 72.248 - Safety analysis report updating.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Safety analysis report updating. 72.248 Section 72.248... Approval of Spent Fuel Storage Casks § 72.248 Safety analysis report updating. (a) Each certificate holder... section, the final safety analysis report (FSAR) to assure that the information included in the...

  5. 10 CFR 72.248 - Safety analysis report updating.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Safety analysis report updating. 72.248 Section 72.248 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF... Approval of Spent Fuel Storage Casks § 72.248 Safety analysis report updating. (a) Each certificate...

  6. 10 CFR 72.248 - Safety analysis report updating.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Safety analysis report updating. 72.248 Section 72.248 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF... Approval of Spent Fuel Storage Casks § 72.248 Safety analysis report updating. (a) Each certificate...

  7. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.127 Renewal...

  8. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.124...

  9. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.124...

  10. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.124...

  11. 17 CFR 248.101 - Purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Purpose and scope. 248.101 Section 248.101 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.101 Purpose and scope....

  12. 17 CFR 248.101 - Purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Purpose and scope. 248.101 Section 248.101 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.101 Purpose and scope....

  13. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.127 Renewal...

  14. 17 CFR 248.126 - Delivery of opt out notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Delivery of opt out notices. 248.126 Section 248.126 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.126...

  15. 10 CFR 72.248 - Safety analysis report updating.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Safety analysis report updating. 72.248 Section 72.248 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF... Approval of Spent Fuel Storage Casks § 72.248 Safety analysis report updating. (a) Each certificate holder...

  16. 10 CFR 72.248 - Safety analysis report updating.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Safety analysis report updating. 72.248 Section 72.248 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF... Approval of Spent Fuel Storage Casks § 72.248 Safety analysis report updating. (a) Each certificate holder...

  17. 25 CFR 248.2 - Persons eligible to use sites.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Persons eligible to use sites. 248.2 Section 248.2... INDIAN IN-LIEU FISHING SITES § 248.2 Persons eligible to use sites. The in-lieu fishing sites are for the... is accordance with treaty rights. The use of the sites is restricted to such Indians; however,...

  18. 25 CFR 248.2 - Persons eligible to use sites.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Persons eligible to use sites. 248.2 Section 248.2... INDIAN IN-LIEU FISHING SITES § 248.2 Persons eligible to use sites. The in-lieu fishing sites are for the... is accordance with treaty rights. The use of the sites is restricted to such Indians; however,...

  19. 7 CFR 248.26 - OMB control number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false OMB control number. 248.26 Section 248.26 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.26...

  20. 7 CFR 248.26 - OMB control number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false OMB control number. 248.26 Section 248.26 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.26...

  1. 7 CFR 248.26 - OMB control number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false OMB control number. 248.26 Section 248.26 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.26...

  2. 7 CFR 248.26 - OMB control number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false OMB control number. 248.26 Section 248.26 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.26...

  3. 7 CFR 58.248 - Nonfat dry milk.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Nonfat dry milk. 58.248 Section 58.248 Agriculture... Products Bearing Usda Official Identification § 58.248 Nonfat dry milk. (a) Nonfat dry milk in commercial....S. Standard Grade. (b) Regular nonfat dry milk in consumer size packages which bears an official...

  4. 7 CFR 58.248 - Nonfat dry milk.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Nonfat dry milk. 58.248 Section 58.248 Agriculture... Products Bearing Usda Official Identification § 58.248 Nonfat dry milk. (a) Nonfat dry milk in commercial....S. Standard Grade. (b) Regular nonfat dry milk in consumer size packages which bears an official...

  5. 7 CFR 58.248 - Nonfat dry milk.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Nonfat dry milk. 58.248 Section 58.248 Agriculture... Products Bearing Usda Official Identification § 58.248 Nonfat dry milk. (a) Nonfat dry milk in commercial....S. Standard Grade. (b) Regular nonfat dry milk in consumer size packages which bears an official...

  6. 7 CFR 58.248 - Nonfat dry milk.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Nonfat dry milk. 58.248 Section 58.248 Agriculture... Products Bearing Usda Official Identification § 58.248 Nonfat dry milk. (a) Nonfat dry milk in commercial....S. Standard Grade. (b) Regular nonfat dry milk in consumer size packages which bears an...

  7. 248nm silicon photoablation: Microstructuring basics

    SciTech Connect

    Poopalan, P.; Najamudin, S. H.; Wahab, Y.; Mazalan, M.

    2015-05-15

    248nm pulses from a KrF excimer laser was used to ablate a Si wafer in order to ascertain the laser pulse and energy effects for use as a microstructuring tool for MEMS fabrication. The laser pulses were varied between two different energy levels of 8mJ and 4mJ while the number of pulses for ablation was varied. The corresponding ablated depths were found to range between 11 µm and 49 µm, depending on the demagnified beam fluence.

  8. NIR flaring of the blazar OJ248

    NASA Astrophysics Data System (ADS)

    Carrasco, L.; Carramiñana, A.; Recillas, E.; Porras, A.; Valdes, J. R.; Escobedo, G.; Torres, I.

    2010-09-01

    We report on our recent observation of the blazar OJ248 also known as 3EGJ0829+2413 and B2 0827+24 with the CANICA NIR camera on the 2.1m telescope at the Observatorio Astrofísico Guillermo Haro, located in Cananea, Mexico. On September 30th, 2010 (JD245554569.9898), we found this source to be in outburst. On this date the source was found to have a flux corresponding to H = 14.59 +/- 0.02, J=15.29 +/- 0.04 and Ks = 13.72 +/- 0.06.

  9. 248nm silicon photoablation: Microstructuring basics

    NASA Astrophysics Data System (ADS)

    Poopalan, P.; Najamudin, S. H.; Wahab, Y.; Mazalan, M.

    2015-05-01

    248nm pulses from a KrF excimer laser was used to ablate a Si wafer in order to ascertain the laser pulse and energy effects for use as a microstructuring tool for MEMS fabrication. The laser pulses were varied between two different energy levels of 8mJ and 4mJ while the number of pulses for ablation was varied. The corresponding ablated depths were found to range between 11 µm and 49 µm, depending on the demagnified beam fluence.

  10. 25 CFR 248.1 - Fishing sites subject to regulation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Fishing sites subject to regulation. 248.1 Section 248.1... INDIAN IN-LIEU FISHING SITES § 248.1 Fishing sites subject to regulation. Use of any of the lands... March 2, 1945 (59 Stat. 22), as amended (hereinafter called “in lieu fishing sites” or “sites”) to...

  11. 25 CFR 248.1 - Fishing sites subject to regulation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Fishing sites subject to regulation. 248.1 Section 248.1... INDIAN IN-LIEU FISHING SITES § 248.1 Fishing sites subject to regulation. Use of any of the lands... March 2, 1945 (59 Stat. 22), as amended (hereinafter called “in lieu fishing sites” or “sites”) to...

  12. 25 CFR 248.1 - Fishing sites subject to regulation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Fishing sites subject to regulation. 248.1 Section 248.1... INDIAN IN-LIEU FISHING SITES § 248.1 Fishing sites subject to regulation. Use of any of the lands... March 2, 1945 (59 Stat. 22), as amended (hereinafter called “in lieu fishing sites” or “sites”) to...

  13. 25 CFR 248.1 - Fishing sites subject to regulation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Fishing sites subject to regulation. 248.1 Section 248.1... INDIAN IN-LIEU FISHING SITES § 248.1 Fishing sites subject to regulation. Use of any of the lands... March 2, 1945 (59 Stat. 22), as amended (hereinafter called “in lieu fishing sites” or “sites”)...

  14. 25 CFR 248.1 - Fishing sites subject to regulation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Fishing sites subject to regulation. 248.1 Section 248.1... INDIAN IN-LIEU FISHING SITES § 248.1 Fishing sites subject to regulation. Use of any of the lands... March 2, 1945 (59 Stat. 22), as amended (hereinafter called “in lieu fishing sites” or “sites”)...

  15. R248Q mutation--Beyond p53-DNA binding.

    PubMed

    Ng, Jeremy W K; Lama, Dilraj; Lukman, Suryani; Lane, David P; Verma, Chandra S; Sim, Adelene Y L

    2015-12-01

    R248 in the DNA binding domain (DBD) of p53 interacts directly with the minor groove of DNA. Earlier nuclear magnetic resonance (NMR) studies indicated that the R248Q mutation resulted in conformation changes in parts of DBD far from the mutation site. However, how information propagates from the mutation site to the rest of the DBD is still not well understood. We performed a series of all-atom molecular dynamics (MD) simulations to dissect sterics and charge effects of R248 on p53-DBD conformation: (i) wild-type p53 DBD; (ii) p53 DBD with an electrically neutral arginine side-chain; (iii) p53 DBD with R248A; (iv) p53 DBD with R248W; and (v) p53 DBD with R248Q. Our results agree well with experimental observations of global conformational changes induced by the R248Q mutation. Our simulations suggest that both charge- and sterics are important in the dynamics of the loop (L3) where the mutation resides. We show that helix 2 (H2) dynamics is altered as a result of a change in the hydrogen bonding partner of D281. In turn, neighboring L1 dynamics is altered: in mutants, L1 predominantly adopts the recessed conformation and is unable to interact with the major groove of DNA. We focused our attention the R248Q mutant that is commonly found in a wide range of cancer and observed changes at the zinc-binding pocket that might account for the dominant negative effects of R248Q. Furthermore, in our simulations, the S6/S7 turn was more frequently solvent exposed in R248Q, suggesting that there is a greater tendency of R248Q to partially unfold and possibly lead to an increased aggregation propensity. Finally, based on the observations made in our simulations, we propose strategies for the rescue of R248Q mutants.

  16. 28 CFR 2.48 - Revocation: Preliminary interview.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Revocation: Preliminary interview. 2.48 Section 2.48 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT... violated his parole as charged, and if so, whether a revocation hearing should be conducted. The...

  17. 28 CFR 2.48 - Revocation: Preliminary interview.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Revocation: Preliminary interview. 2.48 Section 2.48 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT... violated his parole as charged, and if so, whether a revocation hearing should be conducted. The...

  18. 24 CFR 248.223 - Alternative State strategy.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Alternative State strategy. 248.223... Preservation Act of 1987 § 248.223 Alternative State strategy. (a) The Commissioner may approve a State strategy providing for State approval of plans of action that involve termination of low income...

  19. 27 CFR 19.248 - Standard effective tax rate.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Standard effective tax rate. 19.248 Section 19.248 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Distilled Spirits Taxes Effective Tax...

  20. 24 CFR 248.181 - Notice to tenants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Notice to tenants. 248.181 Section 248.181 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN...

  1. 17 CFR 248.17 - Relation to State laws.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Relation to State laws. 248.17... Information Relation to Other Laws; Effective Date § 248.17 Relation to State laws. (a) In general. This... inconsistency. (b) Greater protection under State law. For purposes of this section, a State statute,...

  2. 24 CFR 248.103 - General prepayment limitation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false General prepayment limitation. 248.103 Section 248.103 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND...

  3. 7 CFR 248.21 - Procurement and property management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Procurement and property management. 248.21 Section 248.21 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous...

  4. 7 CFR 248.14 - Distribution of funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Distribution of funds. 248.14 Section 248.14 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  5. 7 CFR 248.11 - Financial management system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Financial management system. 248.11 Section 248.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  6. 7 CFR 248.5 - Selection of new State agencies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Selection of new State agencies. 248.5 Section 248.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility...

  7. 14 CFR 248.5 - Withholding from public disclosure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Withholding from public disclosure. 248.5 Section 248.5 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION... order of the BTS, if such treatment is requested by the air carrier at the time of filing. ...

  8. 24 CFR 248.415 - Delivery of assistance through intermediaries.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Delivery of assistance through intermediaries. 248.415 Section 248.415 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN...

  9. 50 CFR 665.248 - Monk seal protective measures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Monk seal protective measures. 665.248 Section 665.248 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... this section are amended to respond to the problem; (ii) Until other action that will respond to the...

  10. 50 CFR 665.248 - Monk seal protective measures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Monk seal protective measures. 665.248 Section 665.248 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... this section are amended to respond to the problem; (ii) Until other action that will respond to the...

  11. 50 CFR 665.248 - Monk seal protective measures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Monk seal protective measures. 665.248 Section 665.248 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... this section are amended to respond to the problem; (ii) Until other action that will respond to the...

  12. 50 CFR 665.248 - Monk seal protective measures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Monk seal protective measures. 665.248 Section 665.248 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... this section are amended to respond to the problem; (ii) Until other action that will respond to the...

  13. 50 CFR 665.248 - Monk seal protective measures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Monk seal protective measures. 665.248 Section 665.248 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... this section are amended to respond to the problem; (ii) Until other action that will respond to the...

  14. 17 CFR 248.1 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Purpose and scope. 248.1 Section 248.1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding...

  15. 24 CFR 248.234 - Section 8 rental assistance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.234 Section 8 rental assistance. (a) When providing rental... the revised plan of action, notwithstanding § 248.221, that involves the termination of...

  16. 31 CFR 248.6 - Recovery of original check.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false Recovery of original check. 248.6... § 248.6 Recovery of original check. (a) If the claimant recovers an original check after he has... substitute check has been received prior to the recovery of the original check, the original check should...

  17. 31 CFR 248.6 - Recovery of original check.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Recovery of original check. 248.6... § 248.6 Recovery of original check. (a) If the claimant recovers an original check after he has... substitute check has been received prior to the recovery of the original check, the original check should...

  18. 17 CFR 248.126 - Delivery of opt out notices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Delivery of opt out notices. 248.126 Section 248.126 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Internet Web site at which the consumer obtained a product or service electronically and requires the...

  19. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Internet Web site at which the consumer has obtained a product or service. The consumer...

  20. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Renewal of opt out elections. 248.127 Section 248.127 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §...

  1. 17 CFR 248.124 - Reasonable opportunity to opt out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Reasonable opportunity to opt out. 248.124 Section 248.124 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §...

  2. 17 CFR 248.17 - Relation to State laws.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Relation to State laws. 248.17 Section 248.17 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding...

  3. 7 CFR 248.5 - Selection of new State agencies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Selection of new State agencies. 248.5 Section 248.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility...

  4. 7 CFR 248.11 - Financial management system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Financial management system. 248.11 Section 248.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  5. 7 CFR 248.21 - Procurement and property management.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Procurement and property management. 248.21 Section 248.21 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous...

  6. 7 CFR 248.14 - Distribution of funds.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Distribution of funds. 248.14 Section 248.14 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  7. 7 CFR 248.10 - Coupon and market management.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Coupon and market management. 248.10 Section 248.10 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  8. 7 CFR 248.11 - Financial management system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Financial management system. 248.11 Section 248.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  9. 7 CFR 248.11 - Financial management system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Financial management system. 248.11 Section 248.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  10. 7 CFR 248.11 - Financial management system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Financial management system. 248.11 Section 248.11 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  11. 7 CFR 248.10 - Coupon and market management.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Coupon and market management. 248.10 Section 248.10 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  12. 7 CFR 248.21 - Procurement and property management.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Procurement and property management. 248.21 Section 248.21 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous...

  13. 7 CFR 248.14 - Distribution of funds.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Distribution of funds. 248.14 Section 248.14 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  14. 7 CFR 248.21 - Procurement and property management.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Procurement and property management. 248.21 Section 248.21 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous...

  15. 7 CFR 248.10 - Coupon and market management.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Coupon and market management. 248.10 Section 248.10 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  16. 7 CFR 248.14 - Distribution of funds.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Distribution of funds. 248.14 Section 248.14 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  17. 7 CFR 248.14 - Distribution of funds.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Distribution of funds. 248.14 Section 248.14 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Provisions...

  18. 7 CFR 248.5 - Selection of new State agencies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Selection of new State agencies. 248.5 Section 248.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility...

  19. 7 CFR 248.5 - Selection of new State agencies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Selection of new State agencies. 248.5 Section 248.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility...

  20. 7 CFR 248.21 - Procurement and property management.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Procurement and property management. 248.21 Section 248.21 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous...

  1. 7 CFR 248.5 - Selection of new State agencies.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Selection of new State agencies. 248.5 Section 248.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) State Agency Eligibility...

  2. 24 CFR 248.223 - Alternative State strategy.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Alternative State strategy. 248.223... Preservation Act of 1987 § 248.223 Alternative State strategy. (a) The Commissioner may approve a State strategy providing for State approval of plans of action that involve termination of low income...

  3. 24 CFR 248.223 - Alternative State strategy.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Alternative State strategy. 248.223... Preservation Act of 1987 § 248.223 Alternative State strategy. (a) The Commissioner may approve a State strategy providing for State approval of plans of action that involve termination of low income...

  4. 24 CFR 248.223 - Alternative State strategy.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Alternative State strategy. 248.223... Preservation Act of 1987 § 248.223 Alternative State strategy. (a) The Commissioner may approve a State strategy providing for State approval of plans of action that involve termination of low income...

  5. 24 CFR 248.223 - Alternative State strategy.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Alternative State strategy. 248.223... Preservation Act of 1987 § 248.223 Alternative State strategy. (a) The Commissioner may approve a State strategy providing for State approval of plans of action that involve termination of low income...

  6. 25 CFR 248.9 - Camping and use restrictions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-LIEU FISHING SITES § 248.9 Camping and use restrictions. All camping, picnicking, use of alcoholic beverages, setting or use of fires, use of the sites for cleaning of fish, the deposit of any garbage, paper...

  7. 25 CFR 248.9 - Camping and use restrictions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-LIEU FISHING SITES § 248.9 Camping and use restrictions. All camping, picnicking, use of alcoholic beverages, setting or use of fires, use of the sites for cleaning of fish, the deposit of any garbage, paper...

  8. 25 CFR 248.9 - Camping and use restrictions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-LIEU FISHING SITES § 248.9 Camping and use restrictions. All camping, picnicking, use of alcoholic beverages, setting or use of fires, use of the sites for cleaning of fish, the deposit of any garbage, paper...

  9. 25 CFR 248.9 - Camping and use restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-LIEU FISHING SITES § 248.9 Camping and use restrictions. All camping, picnicking, use of alcoholic beverages, setting or use of fires, use of the sites for cleaning of fish, the deposit of any garbage, paper...

  10. 25 CFR 248.9 - Camping and use restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-LIEU FISHING SITES § 248.9 Camping and use restrictions. All camping, picnicking, use of alcoholic beverages, setting or use of fires, use of the sites for cleaning of fish, the deposit of any garbage, paper...

  11. 24 CFR 248.217 - Revisions to plan of action.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.217 Revisions to plan of action. The owner may from time to...

  12. 24 CFR 248.215 - Notification of deficiencies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.215 Notification of deficiencies. Not later than 60 days...

  13. Atomic Mass and Nuclear Binding Energy for Pa-248 (Protactinium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Pa-248 (Protactinium, atomic number Z = 91, mass number A = 248).

  14. 248 mine, Terlingua quicksilver district, Brewster County, Texas

    USGS Publications Warehouse

    Yates, Robert G.; Thompson, George A.

    1944-01-01

    The 248 quicksilver mine is in Section 248, Block G-4, 2 miles east of Terlingua and 86 miles by dirt road from Alpine, Tex., the nearest railway shipping point (see accompanying maps). Cinnabar, the quicksilver mineral, was discovered before 1902. By 1934 there were only about 700 feet of subsurface workings, but in recent years the Esperado Mining Co., which has the property under lease, has greatly extended exploratory workings and has built a Herreshoff furnace rated at 40 tons per day. At the present time there are 1 1/3 miles of underground workings and 800 feet of surface trenches.

  15. Atomic Mass and Nuclear Binding Energy for At-248 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-248 (Astatine, atomic number Z = 85, mass number A = 248).

  16. Atomic Mass and Nuclear Binding Energy for Ac-248 (Actinium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Ac-248 (Actinium, atomic number Z = 89, mass number A = 248).

  17. Atomic Mass and Nuclear Binding Energy for Fm-248 (Fermium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Fm-248 (Fermium, atomic number Z = 100, mass number A = 248).

  18. Atomic Mass and Nuclear Binding Energy for Bk-248 (Berkelium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Bk-248 (Berkelium, atomic number Z = 97, mass number A = 248).

  19. 17 CFR 248.18 - Effective date; transition rule.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... customers on the compliance date. By July 1, 2001, you must have provided an initial notice, as required by § 248.4, to consumers who are your customers on July 1, 2001. (2) Example. You provide an initial notice to consumers who are your customers on July 1, 2001, if, by that date, you have established a...

  20. 47 CFR 90.248 - Wildlife and ocean buoy tracking.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Wildlife and ocean buoy tracking. 90.248... and ocean buoy tracking. (a) The frequency bands 40.66-40.70 MHz and 216-220 MHz may be used for the tracking of, and the telemetry of scientific data from, ocean buoys and animal wildlife. (b) Transmitters...

  1. 47 CFR 90.248 - Wildlife and ocean buoy tracking.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Wildlife and ocean buoy tracking. 90.248... and ocean buoy tracking. (a) The frequency bands 40.66-40.70 MHz and 216-220 MHz may be used for the tracking of, and the telemetry of scientific data from, ocean buoys and animal wildlife. (b) Transmitters...

  2. 47 CFR 90.248 - Wildlife and ocean buoy tracking.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Wildlife and ocean buoy tracking. 90.248... and ocean buoy tracking. (a) The frequency bands 40.66-40.70 MHz and 216-220 MHz may be used for the tracking of, and the telemetry of scientific data from, ocean buoys and animal wildlife. (b) Transmitters...

  3. 47 CFR 90.248 - Wildlife and ocean buoy tracking.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Wildlife and ocean buoy tracking. 90.248... and ocean buoy tracking. (a) The frequency bands 40.66-40.70 MHz and 216-220 MHz may be used for the tracking of, and the telemetry of scientific data from, ocean buoys and animal wildlife. (b) Transmitters...

  4. 47 CFR 90.248 - Wildlife and ocean buoy tracking.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Wildlife and ocean buoy tracking. 90.248... and ocean buoy tracking. (a) The frequency bands 40.66-40.70 MHz and 216-220 MHz may be used for the tracking of, and the telemetry of scientific data from, ocean buoys and animal wildlife. (b) Transmitters...

  5. 7 CFR 248.23 - Records and reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.23..., FMNP coupon issuance and redemption, equipment purchases and inventory, nutrition education, and civil...

  6. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To provide...

  7. 24 CFR 248.410 - Grants for other purposes.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Technical Assistance and Capacity Building § 248.410 Grants for... community-based nonprofit organizations with experience in resident education and organizing for the purpose of conducting community, city or countywide outreach and training programs to identify and...

  8. 47 CFR 1.248 - Prehearing conferences; hearing conferences.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Prehearing conferences; hearing conferences. 1... Hearing Proceedings Prehearing Procedures § 1.248 Prehearing conferences; hearing conferences. (a) The... to appear at a specified time and place for a conference prior to a hearing, or to submit...

  9. 248. Smart view Recreation Area. View of one of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    248. Smart view Recreation Area. View of one of the parkway curves with a snake fence on the left and a stone drain on the right reinforcing the roadway alignment. Looking north-northeast. - Blue Ridge Parkway, Between Shenandoah National Park & Great Smoky Mountains, Asheville, Buncombe County, NC

  10. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Renewal of opt out elections... opt out elections. (a) Renewal notice and opt out requirement—(1) In general. After the opt out period... through 248.126, and a reasonable opportunity and a reasonable and simple method to renew the opt out, and...

  11. 17 CFR 248.127 - Renewal of opt out elections.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Renewal of opt out elections... opt out elections. (a) Renewal notice and opt out requirement—(1) In general. After the opt out period... through 248.126, and a reasonable opportunity and a reasonable and simple method to renew the opt out, and...

  12. 24 CFR 248.203 - General prepayment limitation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.203 General prepayment limitation. (a) An owner of eligible low... to eligible low income housing may be terminated pursuant to section 229 of the National Housing...

  13. 24 CFR 248.211 - Notice of intent to prepay.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.211 Notice of intent to prepay. (a) An owner of eligible low-income housing... of this part regarding the approval of a plan of action involving termination of low...

  14. 48 CFR 52.248-1 - Value Engineering.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Value Engineering. 52.248... Value Engineering. As prescribed in 48.201, insert the following clause: Value Engineering (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit value engineering change proposals...

  15. 48 CFR 52.248-3 - Value Engineering-Construction.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

  16. 48 CFR 52.248-1 - Value Engineering.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Value Engineering. 52.248... Value Engineering. As prescribed in 48.201, insert the following clause: Value Engineering (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit value engineering change proposals...

  17. 48 CFR 52.248-3 - Value Engineering-Construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

  18. 48 CFR 52.248-1 - Value Engineering.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Value Engineering. 52.248... Value Engineering. As prescribed in 48.201, insert the following clause: Value Engineering (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit value engineering change proposals...

  19. 48 CFR 52.248-3 - Value Engineering-Construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

  20. 48 CFR 52.248-3 - Value Engineering-Construction.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Value Engineering....248-3 Value Engineering—Construction. As prescribed in 48.202, insert the following clause: Value Engineering—Construction (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit...

  1. 48 CFR 52.248-1 - Value Engineering.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Value Engineering. 52.248... Value Engineering. As prescribed in 48.201, insert the following clause: Value Engineering (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit value engineering change proposals...

  2. 48 CFR 52.248-1 - Value Engineering.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Value Engineering. 52.248... Value Engineering. As prescribed in 48.201, insert the following clause: Value Engineering (OCT 2010) (a) General. The Contractor is encouraged to develop, prepare, and submit value engineering change proposals...

  3. 24 CFR 248.165 - Assistance for displaced tenants.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of the displaced tenants who are special needs tenants, as that term is defined in § 248.101, as well as a statement as to the nature of their special need. The owner shall provide the Commissioner with... projects located in a low-vacancy area; and (2) Special needs tenants. (h) Low Vacancy Areas....

  4. 24 CFR 248.165 - Assistance for displaced tenants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of the displaced tenants who are special needs tenants, as that term is defined in § 248.101, as well as a statement as to the nature of their special need. The owner shall provide the Commissioner with... projects located in a low-vacancy area; and (2) Special needs tenants. (h) Low Vacancy Areas....

  5. 17 CFR 248.101 - Purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing § 248.101 Purpose and... Fair and Accurate Credit Transactions Act of 2003, Public Law 108-159, 117 Stat. 1952 (2003) (“FACT Act” or “Act”), regulates the use of consumer information received from an affiliate to make...

  6. 17 CFR 248.101 - Purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.101 Purpose and scope. (a... Accurate Credit Transactions Act of 2003, Public Law 108-159, 117 Stat. 1952 (2003) (“FACT Act” or “Act”), regulates the use of consumer information received from an affiliate to make marketing solicitations....

  7. 17 CFR 248.101 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.101 Purpose and scope. (a... Accurate Credit Transactions Act of 2003, Public Law 108-159, 117 Stat. 1952 (2003) (“FACT Act” or “Act”), regulates the use of consumer information received from an affiliate to make marketing solicitations....

  8. High average power, narrow band 248 nm alexandrite laser system

    SciTech Connect

    Kuper, J.W.; Chin, T.C.; Papanestor, P.A.

    1994-12-31

    A compact line-narrowed 248 nm solid state laser source operating at 15 mJ {at} 100 Hz PRF was demonstrated. Constraints due to thermal loading of components were addressed. Tradeoffs between pulse energy and repetition rate were investigated. A method for overcoming thermal dephasing in the THG material was achieved by scanning a slab shaped crystal.

  9. Swift follow-up of the flaring blazar OJ 248

    NASA Astrophysics Data System (ADS)

    D'Ammando, F.; Orienti, M.

    2012-10-01

    Following the gamma-ray flaring activity of the flat spectrum radio quasar OJ 248 (also known as 2FGL J0830.5+2407, Nolan et al. 2012, ApJS, 199, 31) detected by Fermi LAT starting from 2012 September 23 (ATel #4421) a Swift target of opportunity observation was performed on September 28.

  10. 42 CFR 403.248 - Administrative review of CMS determinations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 2 2013-10-01 2013-10-01 false Administrative review of CMS determinations. 403... Certification Program: General Provisions § 403.248 Administrative review of CMS determinations. (a) This section provides for administrative review if CMS determines— (1) Not to certify a policy; or (2) That...

  11. 42 CFR 403.248 - Administrative review of CMS determinations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Administrative review of CMS determinations. 403... Certification Program: General Provisions § 403.248 Administrative review of CMS determinations. (a) This section provides for administrative review if CMS determines— (1) Not to certify a policy; or (2) That...

  12. 42 CFR 403.248 - Administrative review of CMS determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 2 2012-10-01 2012-10-01 false Administrative review of CMS determinations. 403... Certification Program: General Provisions § 403.248 Administrative review of CMS determinations. (a) This section provides for administrative review if CMS determines— (1) Not to certify a policy; or (2) That...

  13. 17 CFR 248.1 - Purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information § 248.1 Purpose and scope. (a) Purpose. This subpart governs the treatment of nonpublic personal... about individuals who obtain financial products or services primarily for personal, family, or...

  14. 17 CFR 248.1 - Purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information § 248.1 Purpose and scope. (a) Purpose. This subpart governs the treatment of nonpublic personal... about individuals who obtain financial products or services primarily for personal, family, or...

  15. 17 CFR 248.1 - Purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information § 248.1 Purpose and scope. (a) Purpose. This subpart governs the treatment of nonpublic personal... about individuals who obtain financial products or services primarily for personal, family, or...

  16. 17 CFR 248.8 - Revised privacy notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.8 Revised privacy notices. (a) General rule. Except... any nonpublic personal information about a consumer to a nonaffiliated third party other than...

  17. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To provide...

  18. 7 CFR 248.23 - Records and reports.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.23..., FMNP coupon issuance and redemption, equipment purchases and inventory, nutrition education, and civil...

  19. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To provide...

  20. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To provide...

  1. 7 CFR 248.23 - Records and reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.23..., FMNP coupon issuance and redemption, equipment purchases and inventory, nutrition education, and civil...

  2. 7 CFR 248.1 - General purpose and scope.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) General § 248.1 General... out the WIC Farmers' Market Nutrition Program. The dual purposes of the FMNP are: (a) To provide...

  3. 7 CFR 248.23 - Records and reports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.23..., FMNP coupon issuance and redemption, equipment purchases and inventory, nutrition education, and civil...

  4. 7 CFR 248.23 - Records and reports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.23..., FMNP coupon issuance and redemption, equipment purchases and inventory, nutrition education, and civil...

  5. Experimental study of 248nm excimer laser etching of alumina

    NASA Astrophysics Data System (ADS)

    Hu, Hongtao; Shao, Jingzhen; Wang, Xi; Fang, Xiaodong

    2016-10-01

    The 248 nm excimer laser etching characteristic of alumina ceramic and sapphire had been studied using different laser fluence and different number of pulses. And the interaction mechanism of 248 nm excimer laser with alumina ceramic and sapphire had been analyzed. The results showed that when the laser fluence was less than 8 J/cm2, the etching depth of alumina ceramic and sapphire were increased with the increase of laser fluence and number of pulses. At the high number pulses and high-energy, the surface of the sapphire had no obvious melting phenomenon, and the alumina ceramic appeared obvious melting phenomenon. The interaction mechanism of excimer laser with alumina ceramics and sapphire was mainly two-photon absorption. But because of the existence of impurities and defects, the coupling between the laser radiation and ceramic and sapphire was strong, and the thermal evaporation mechanism was also obvious.

  6. Search for Cm-248 in the early solar system

    NASA Technical Reports Server (NTRS)

    Lavielle, B.; Marti, K.; Pellas, P.; Perron, C.

    1992-01-01

    Possible evidence for the presence of Cm-248 in the early solar system was reported from fission gas studies (Rao and Gopalan, 1973) and recently from studies of very high nuclear track densities (not less than 5 x 10 exp 8/sq cm) in the merrillite of the H4 chondrite Forest Vale (F.V.) (Pellas et al., 1987). We report here an analysis of the isotopic abundances of xenon in F.V. phosphates and results of track studies in phosphate/pyroxene contacts. The fission xenon isotopic signature clearly identifies Pu-244 as the extinct progenitor. We calculate an upper limit Cm-248/Pu-244 to be less than 0.0015 at the beginning of Xe retention in F.V. phosphates. This corresponds to an upper limit of the ratio Cm-248/U-235 of not greater than 5 x 10 exp -5 further constraining the evidence for any late addition of freshly synthesized actinide elements just prior to solar system formation. The fission track density observed after annealing the phosphates at 290C (1 hr, which essentially erases spallation recoil tracks) is also in agreement with the Pu-244 abundance inferred from fission Xe. The spallation recoil tracks produced during the 76 Ma cosmic-ray exposure account for the very high track density in merrillites.

  7. 25 CFR 248.5 - Damage to Government-owned property.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Damage to Government-owned property. 248.5 Section 248.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE USE OF COLUMBIA RIVER INDIAN IN-LIEU FISHING SITES § 248.5 Damage to Government-owned property. Anyone committing any act of...

  8. 25 CFR 248.5 - Damage to Government-owned property.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Damage to Government-owned property. 248.5 Section 248.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE USE OF COLUMBIA RIVER INDIAN IN-LIEU FISHING SITES § 248.5 Damage to Government-owned property. Anyone committing any act of...

  9. 25 CFR 248.5 - Damage to Government-owned property.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Damage to Government-owned property. 248.5 Section 248.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE USE OF COLUMBIA RIVER INDIAN IN-LIEU FISHING SITES § 248.5 Damage to Government-owned property. Anyone committing any act of...

  10. 25 CFR 248.5 - Damage to Government-owned property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Damage to Government-owned property. 248.5 Section 248.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE USE OF COLUMBIA RIVER INDIAN IN-LIEU FISHING SITES § 248.5 Damage to Government-owned property. Anyone committing any act of...

  11. 25 CFR 248.5 - Damage to Government-owned property.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Damage to Government-owned property. 248.5 Section 248.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FISH AND WILDLIFE USE OF COLUMBIA RIVER INDIAN IN-LIEU FISHING SITES § 248.5 Damage to Government-owned property. Anyone committing any act of...

  12. 17 CFR 248.5 - Annual privacy notice to customers required.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... customers required. 248.5 Section 248.5 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Safeguarding Personal Information Privacy and Opt Out Notices § 248.5 Annual privacy notice to customers required. (a)(1) General rule. You must provide a clear and conspicuous notice to customers that...

  13. 17 CFR 248.201 - Duties regarding the detection, prevention, and mitigation of identity theft.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., prevention, and mitigation of identity theft. 248.201 Section 248.201 Commodity and Securities Exchanges... Theft Red Flags § 248.201 Duties regarding the detection, prevention, and mitigation of identity theft... institution or creditor from identity theft, including financial, operational, compliance, reputation,...

  14. 33 CFR 148.248 - What happens when a document does not contain all necessary information?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What happens when a document does not contain all necessary information? 148.248 Section 148.248 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: GENERAL Processing Applications Formal Hearings § 148.248...

  15. 24 CFR 248.405 - Grants for building resident capacity and funding predevelopment costs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... capacity and funding predevelopment costs. 248.405 Section 248.405 Housing and Urban Development... Technical Assistance and Capacity Building § 248.405 Grants for building resident capacity and funding... available under this subpart shall be used for resident capacity grants in accordance with paragraph (d) of...

  16. 42 CFR 24.8 - Applicability of provisions of Title 5, U.S. Code.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Applicability of provisions of Title 5, U.S. Code. 24.8 Section 24.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.8 Applicability of provisions of Title 5, U.S. Code....

  17. 42 CFR 24.8 - Applicability of provisions of Title 5, U.S. Code.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Applicability of provisions of Title 5, U.S. Code. 24.8 Section 24.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.8 Applicability of provisions of Title 5, U.S. Code....

  18. 42 CFR 24.8 - Applicability of provisions of Title 5, U.S. Code.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Applicability of provisions of Title 5, U.S. Code. 24.8 Section 24.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.8 Applicability of provisions of Title 5, U.S. Code....

  19. 42 CFR 24.8 - Applicability of provisions of Title 5, U.S. Code.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Applicability of provisions of Title 5, U.S. Code. 24.8 Section 24.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.8 Applicability of provisions of Title 5, U.S. Code....

  20. 42 CFR 24.8 - Applicability of provisions of Title 5, U.S. Code.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Applicability of provisions of Title 5, U.S. Code. 24.8 Section 24.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES PERSONNEL SENIOR BIOMEDICAL RESEARCH SERVICE § 24.8 Applicability of provisions of Title 5, U.S. Code....

  1. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Scope and duration of opt out. 248.122 Section 248.122 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.122 Scope...

  2. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Scope and duration of opt out. 248.122 Section 248.122 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.122 Scope...

  3. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Contents of opt out notice; consolidated and equivalent notices. 248.123 Section 248.123 Commodity and Securities Exchanges SECURITIES AND... Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt...

  4. 37 CFR 2.48 - Office does not issue duplicate registrations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Office does not issue duplicate registrations. 2.48 Section 2.48 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES The Written Application § 2.48...

  5. 37 CFR 2.48 - Office does not issue duplicate registrations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Office does not issue duplicate registrations. 2.48 Section 2.48 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES The Written Application § 2.48...

  6. 17 CFR 248.10 - Limits on disclosure of nonpublic personal information to nonaffiliated third parties.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...: Privacy of Consumer Financial Information and Safeguarding Personal Information Limits on Disclosures § 248.10 Limits on disclosure of nonpublic personal information to nonaffiliated third parties. (a)(1... nonpublic personal information to nonaffiliated third parties. 248.10 Section 248.10 Commodity...

  7. 17 CFR 248.10 - Limits on disclosure of nonpublic personal information to nonaffiliated third parties.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...: Privacy of Consumer Financial Information and Safeguarding Personal Information Limits on Disclosures § 248.10 Limits on disclosure of nonpublic personal information to nonaffiliated third parties. (a)(1... nonpublic personal information to nonaffiliated third parties. 248.10 Section 248.10 Commodity...

  8. 17 CFR 248.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.13 Exception to opt... nonpublic personal information under this section to a financial institution with which you perform joint... requirements in §§ 248.7 and 248.10 do not apply when you provide nonpublic personal information to...

  9. 17 CFR 248.4 - Initial privacy notice to consumers required.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... consumers required. 248.4 Section 248.4 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.4 Initial privacy notice to...

  10. [Latency values of 248 H reflexes in 124 normal subjects].

    PubMed

    Goizueta-San Martín, G; Ruiz-Rodríguez, G; Gutiérrez-Gutiérrez, G; Gutiérrez-Rivas, E; Millán-Santos, I

    2010-11-16

    The Hoffmann reflex or H reflex is an electrical counterpart of the myotatic reflex. In normal adults is elicited with stimulating the tibial and the median nerves. It is useful as an adjunct study of neuroexamination and assesses the corresponding arc reflexes in their integrity. 248 H reflexes were studied stimulating the tibial nerve in 124 healthy subjects. The latency values were: minimum 23.6 ms; maximum 29.8 ms; mean value 27.6 ± 1.41 ms. This work explains the technique to obtain the H reflex and discusses the need for normalized values for each neurophysiology lab.

  11. Actinide production from xenon bombardments of curium-248

    SciTech Connect

    Welch, R.B.

    1985-01-01

    Production cross sections for many actinide nuclides formed in the reaction of /sup 129/Xe and /sup 132/Xe with /sup 248/Cm at bombarding energies slightly above the coulomb barrier were determined using radiochemical techniques to isolate these products. These results are compared with cross sections from a /sup 136/Xe + /sup 248/Cm reaction at a similar energy. When compared to the reaction with /sup 136/Xe, the maxima in the production cross section distributions from the more neutron deficient projectiles are shifted to smaller mass numbers, and the total cross section increases for the production of elements with atomic numbers greater than that of the target, and decreases for lighter elements. These results can be explained by use of a potential energy surface (PES) which illustrates the effect of the available energy on the transfer of nucleons and describes the evolution of the di-nuclear complex, an essential feature of deep-inelastic reactions (DIR), during the interaction. The other principal reaction mechanism is the quasi-elastic transfer (QE). Analysis of data from a similar set of reactions, /sup 129/Xe, /sup 132/Xe, and /sup 136/Xe with /sup 197/Au, aids in explaining the features of the Xe + Cm product distributions, which are additionally affected by the depletion of actinide product yields due to deexcitation by fission. The PES is shown to be a useful tool to predict the general features of product distributions from heavy ion reactions.

  12. Breast volume measurement of 248 women using biostereometric analysis.

    PubMed

    Loughry, C W; Sheffer, D B; Price, T E; Lackney, M J; Bartfai, R G; Morek, W M

    1987-10-01

    A study of volumes of the right and left breasts of 248 subjects was undertaken using biostereometric analysis. This measurement technique uses close-range stereophotogrammetry to characterize the shape of the breast and is noncontact, noninvasive, accurate, and rapid with respect to the subject involvement time. Volumes and volumetric differences between breast pairs were compared, using chi-square tests, with handedness, perception of breast size by each subject, age, and menstrual status. No significant relationship was found between the handedness of the subject and the larger breast volume. Several groups of subjects based on age and menstrual status were accurate in their perception of breast size difference. Analysis did not confirm the generally accepted clinical impression of left breast volume dominance. Although a size difference in breast pairs was documented, neither breast predominated.

  13. 7 CFR 248.22 - Nonprocurement debarment/suspension, drug-free workplace, and lobbying restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.22 Nonprocurement debarment...

  14. 7 CFR 248.22 - Nonprocurement debarment/suspension, drug-free workplace, and lobbying restrictions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.22 Nonprocurement debarment...

  15. 7 CFR 248.22 - Nonprocurement debarment/suspension, drug-free workplace, and lobbying restrictions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.22 Nonprocurement debarment...

  16. 7 CFR 248.22 - Nonprocurement debarment/suspension, drug-free workplace, and lobbying restrictions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.22 Nonprocurement debarment...

  17. 7 CFR 248.22 - Nonprocurement debarment/suspension, drug-free workplace, and lobbying restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Miscellaneous Provisions § 248.22 Nonprocurement debarment...

  18. Heavy actinide production from the interactions of sup 40 Ar with sup 248 Cm and a comparison with the sup 44 Ca- sup 248 Cm system

    SciTech Connect

    Leyba, J.D.; Henderson, R.A.; Hall, H.L.; Gannett, C.M.; Chadwick, R.B.; Czerwinski, K.R.; Kadkhodayan, B.A.; Kreek, S.A.; Haynes, G.R.; Gregorich, K.E.; Lee, D.M.; Nurmia, M.J.; Hoffman, D.C. Nuclear Science Division, Lawrence Berkeley Laboratory, University of California, Berkeley, Berkeley, California 94720)

    1990-05-01

    Excitation functions have been measured for isotopes of Bk, Cf, Es, and Fm produced from the interactions of 207- to 286-MeV {sup 40}Ar ions with {sup 248}Cm. The measured isotopic distributions were found to be essentially symmetric with full widths at half maximum between 2.0 and 3.5 mass units. These results are comparable to those obtained in previous studies using {sup 40,44,48}Ca with {sup 248}Cm. The maxima of the isotopic distributions from the {sup 40}Ar-{sup 248}Cm system show shifts, to both heavier and lighter mass numbers, of 0 to 2 mass units relative to the corresponding maxima of the isotopic distributions from the {sup 40,44,48}Ca-{sup 248}Cm systems.

  19. Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis.

    PubMed

    Bartis, Domokos; Crowley, Louise E; D'Souza, Vijay K; Borthwick, Lee; Fisher, Andrew J; Croft, Adam P; Pongrácz, Judit E; Thompson, Richard; Langman, Gerald; Buckley, Christopher D; Thickett, David R

    2016-04-14

    CD248 or Endosialin is a transmembrane molecule expressed in stromal cells binding to extracellular matrix (ECM) components. It has been previously implicated in kidney fibrosis, rheumatoid arthritis as well as in tumour-stromal interactions. This study investigates the role of CD248 in the pathogenesis of fibrotic diseases in Idiopathic Pulmonary Fibrosis (IPF). CD248 quantitative immunohistochemistry (IHC) was performed on lung samples from 22 IPF patients and its expression was assayed in cultured pulmonary fibroblasts and epithelial cells. Effects of CD248 silencing was evaluated on fibroblast proliferation and myofibroblast differentiation. IHC revealed strong CD248 expression in mesenchymal cells of normal lung structures such as pleura and adventitia but not in epithelium. Fibrotic areas showed markedly stronger staining than unaffected lung tissue. The extent of CD248 staining showed a significant negative correlation to lung function parameters FEV1, FVC, TLC, and TLCO (r2 > 0 · 35, p < 0 · 01). CD248 protein levels were significantly greater in IPF-derived lung fibroblasts vs normal lung fibroblasts (p < 0 · 01) and CD248 silencing significantly reduced the proliferation of lung fibroblasts, but did not affected myofibroblast differentiation. We conclude that CD248 overexpression is possibly involved in the pathogenesis of IPF and it has potential as a disease severity marker. Given that CD248 ligands are collagen type I, IV and fibronectin, we hypothesise that CD248 signalling represents a novel matrix-fibroblast interaction that may be a potential therapeutic target in IPF.

  20. Photofragment Translational Spectroscopy of Propargyl Radicals at 248 nm

    SciTech Connect

    Goncher, S.J.; Moore, D.T.; Sveum, N.E.; Neumark, D.M.

    2007-12-21

    The photodissociation of propargyl radical, C{sub 3}H{sub 3}, and its perdeuterated isotopolog was investigated using photofragment translational spectroscopy. Propargyl radicals were produced by 193 nm photolysis of allene entrained in a molecular beam expansion, and then photodissociated at 248 nm. photofragment time-of-flight spectra were measured at a series of laboratory angles using electron impact ionization coupled to a mass spectrometer. Data for ion masses corresponding to C{sub 3}H{sub 2}{sup +}, C{sub 3}H{sup +}, C{sub 3}{sup +}, and the analogous deuterated species show that both H and H{sub 2} loss occur. The translational energy distributions for these processes have average values = 5.7 and 15.9 kcal/mol, respectively, and are consistent with dissociation on the ground state following internal conversion, with no exit barrier for H loss but a tight transition state for H{sub 2} loss. The translational energy distribution for H atom loss is similar to that in previous work on propargyl in which the H atom, rather than the heavy fragment, was detected. The branching ratio for H loss/H{sub 2} loss was determined to be 97.6/2.4 {+-} 1.2, in good agreement with RRKM results.

  1. 42 CFR 412.248 - Number of members needed for a decision or a hearing.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Number of members needed for a decision or a hearing. 412.248 Section 412.248 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM PROSPECTIVE PAYMENT SYSTEMS FOR INPATIENT HOSPITAL SERVICES The Medicare Geographic Classification...

  2. 24 CFR 248.153 - Incentives to extend low income use.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Incentives to extend low income use. 248.153 Section 248.153 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF...

  3. 24 CFR 248.231 - Incentives to extend low income use.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Incentives to extend low income use. 248.231 Section 248.231 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF...

  4. 17 CFR 248.202 - Duties of card issuers regarding changes of address.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Duties of card issuers regarding changes of address. 248.202 Section 248.202 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-ID: Identity Theft Red...

  5. 7 CFR 248.8 - Level of benefits and eligible foods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Level of benefits and eligible foods. 248.8 Section 248.8 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient...

  6. 7 CFR 248.16 - Administrative appeal of State agency decisions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administrative appeal of State agency decisions. 248.16 Section 248.16 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM...

  7. 17 CFR 248.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Delivering privacy and opt out notices. 248.9 Section 248.9 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... customer uses your web site to access financial products and services electronically and agrees to receive...

  8. 24 CFR 248.218 - Tenant notice and opportunity to comment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Tenant notice and opportunity to comment. 248.218 Section 248.218 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT...

  9. 24 CFR 248.218 - Tenant notice and opportunity to comment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Tenant notice and opportunity to comment. 248.218 Section 248.218 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT...

  10. 24 CFR 248.218 - Tenant notice and opportunity to comment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Tenant notice and opportunity to comment. 248.218 Section 248.218 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT...

  11. 24 CFR 248.218 - Tenant notice and opportunity to comment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Tenant notice and opportunity to comment. 248.218 Section 248.218 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT...

  12. 24 CFR 248.218 - Tenant notice and opportunity to comment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Tenant notice and opportunity to comment. 248.218 Section 248.218 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT...

  13. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... electronically mailed or processed at an Internet Web site, if the consumer agrees to the electronic delivery...

  14. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §...

  15. 17 CFR 248.128 - Effective date, compliance date, and prospective application.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Effective date, compliance date, and prospective application. 248.128 Section 248.128 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations...

  16. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Scope and duration of opt out. 248.122 Section 248.122 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing §...

  17. 17 CFR 248.128 - Effective date, compliance date, and prospective application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Effective date, compliance date, and prospective application. 248.128 Section 248.128 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations...

  18. 17 CFR 248.128 - Effective date, compliance date, and prospective application.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Effective date, compliance date, and prospective application. 248.128 Section 248.128 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations...

  19. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate...

  20. 17 CFR 248.128 - Effective date, compliance date, and prospective application.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Effective date, compliance date, and prospective application. 248.128 Section 248.128 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations...

  1. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §...

  2. 17 CFR 248.125 - Reasonable and simple methods of opting out.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Reasonable and simple methods of opting out. 248.125 Section 248.125 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing §...

  3. 17 CFR 248.128 - Effective date, compliance date, and prospective application.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Effective date, compliance date, and prospective application. 248.128 Section 248.128 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM:...

  4. 50 CFR 216.248 - Renewal of Letters of Authorization and Adaptive Management.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Renewal of Letters of Authorization and Adaptive Management. 216.248 Section 216.248 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... are restricted to: (1) New cited information and data indicating that the determinations made in...

  5. 7 CFR 248.16 - Administrative appeal of State agency decisions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Administrative appeal of State agency decisions. 248.16 Section 248.16 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM...

  6. 7 CFR 248.16 - Administrative appeal of State agency decisions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Administrative appeal of State agency decisions. 248.16 Section 248.16 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM...

  7. 7 CFR 248.8 - Level of benefits and eligible foods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Level of benefits and eligible foods. 248.8 Section 248.8 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient...

  8. 7 CFR 248.16 - Administrative appeal of State agency decisions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Administrative appeal of State agency decisions. 248.16 Section 248.16 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM...

  9. 7 CFR 248.16 - Administrative appeal of State agency decisions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Administrative appeal of State agency decisions. 248.16 Section 248.16 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM...

  10. 7 CFR 248.8 - Level of benefits and eligible foods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Level of benefits and eligible foods. 248.8 Section 248.8 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient...

  11. 7 CFR 248.8 - Level of benefits and eligible foods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Level of benefits and eligible foods. 248.8 Section 248.8 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient...

  12. 7 CFR 248.8 - Level of benefits and eligible foods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Level of benefits and eligible foods. 248.8 Section 248.8 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS WIC FARMERS' MARKET NUTRITION PROGRAM (FMNP) Recipient...

  13. 50 CFR 216.248 - Renewal of Letters of Authorization and Adaptive Management.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Renewal of Letters of Authorization and Adaptive Management. 216.248 Section 216.248 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS...

  14. 24 CFR 248.405 - Grants for building resident capacity and funding predevelopment costs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... capacity and funding predevelopment costs. 248.405 Section 248.405 Housing and Urban Development... predevelopment costs. (a) General. Assistance made available under this subpart shall be used for direct... paragraph (e) of this section for predevelopment costs may not exceed $200,000 per project, exclusive of any...

  15. 26 CFR 1.248-1 - Election to amortize organizational expenditures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Election to amortize organizational expenditures... amortize organizational expenditures. (a) For further guidance, see § 1.248-1T(a). (b) Organizational expenditures defined. (1) Section 248(b) defines the term organizational expenditures. Such expenditures,...

  16. Mutant p53 R248Q but not R248W enhances in vitro invasiveness of human lung cancer NCI-H1299 cells.

    PubMed

    Yoshikawa, Kazuhito; Hamada, Jun-ichi; Tada, Mitsuhiro; Kameyama, Takeshi; Nakagawa, Koji; Suzuki, Yukiko; Ikawa, Mayumi; Hassan, Nur Mohammad Monsur; Kitagawa, Yoshimasa; Moriuchi, Tetsuya

    2010-12-01

    More than half of all human cancers are associated with mutations of the TP53 gene. In regard to the functional interaction with the remaining wild-type (WT) p53 allele, p53 mutations are classified into two types, recessive and dominant-negative (DN) mutations. The latter mutant protein has a DN activity over the remaining WT allele. We previously showed that the DN p53 mutant was useful as a predictor of poor outcome or a risk factor for metastatic recurrence in patients with some types of cancers, regardless of the presence or absence of loss of heterozygosity (LOH) of WT p53, suggesting that the DN p53 had 'gain-of-function (GOF)' activity besides the transdominance function. In this study, we investigated GOF activity of two DN p53 mutants which had a point mutation at codon 248 (R248Q and R248W), one of the hot spots, by transfecting them respectively into H1299 cells which originally expressed no p53 protein. Growth activity of the transfectants with the two mutants was not different from that of parent or Mock transfectants. Meanwhile, in vitro invasions of Matrigel and type I collagen gel by R248Q-transfectants were significantly higher than those by R248W-transfectants or the control cells. However, there were no differences in cell motile activities, expressions of extracellular matrix-degradative enzymes such as matrix metalloproteinases, urokinase-type plasminogen activator and heparanase, and their inhibitors, between R248Q- and R248W-transfectants. These findings indicate that the p53 mutants have a different quality in GOF activities even if the mutations occurred at the same codon. And detailed information of the status of p53, including transdominancy and GOF activity, is expected to be useful for diagnosis and therapeutic strategy fitting the individual patients.

  17. A Differential Role for CD248 (Endosialin) in PDGF-Mediated Skeletal Muscle Angiogenesis

    PubMed Central

    Maynard, William D.; May, Philippa; Barone, Francesca; Croft, Adam P.; Egginton, Stuart; Buckley, Christopher D.

    2014-01-01

    CD248 (Endosialin) is a type 1 membrane protein involved in developmental and pathological angiogenesis through its expression on pericytes and regulation of PDGFRβ signalling. Here we explore the function of CD248 in skeletal muscle angiogenesis. Two distinct forms of capillary growth (splitting and sprouting) can be induced separately by increasing microcirculatory shear stress (chronic vasodilator treatment) or by inducing functional overload (extirpation of a synergistic muscle). We show that CD248 is present on pericytes in muscle and that CD248-/- mice have a specific defect in capillary sprouting. In contrast, splitting angiogenesis is independent of CD248 expression. Endothelial cells respond to pro-sprouting angiogenic stimulus by up-regulating gene expression for HIF1α, angiopoietin 2 and its receptor TEK, PDGF-B and its receptor PDGFRβ; this response did not occur following a pro-splitting angiogenic stimulus. In wildtype mice, defective sprouting angiogenesis could be mimicked by blocking PDGFRβ signalling using the tyrosine kinase inhibitor Imatinib mesylate. We conclude that CD248 is required for PDGFRβ-dependant capillary sprouting but not splitting angiogenesis, and identify a new role for CD248 expressed on pericytes in the early stages of physiological angiogenesis during muscle remodelling. PMID:25243742

  18. 17 CFR Appendix A to Subpart A of... - Appendix A to Subpart A of Part 248 Forms

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Appendix A to Subpart A of Part 248 Forms A Appendix A to Subpart A of Part 248 Forms Commodity and Securities Exchanges... Financial Information and Safeguarding Personal Information Pt. 248, Subpt. A, App. A Appendix A to Subpart...

  19. 24 CFR 248.175 - Resident homeownership program-limited equity cooperative.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...)), (m) and (n). (c) The purchase and operation of eligible low income housing by a limited equity... carried out in accordance with the provisions of § 248.173 (a), (b), (c), (d), (except that paragraph (d...

  20. 24 CFR 248.175 - Resident homeownership program-limited equity cooperative.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...)), (m) and (n). (c) The purchase and operation of eligible low income housing by a limited equity... carried out in accordance with the provisions of § 248.173 (a), (b), (c), (d), (except that paragraph (d...

  1. 24 CFR 248.175 - Resident homeownership program-limited equity cooperative.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...)), (m) and (n). (c) The purchase and operation of eligible low income housing by a limited equity... carried out in accordance with the provisions of § 248.173 (a), (b), (c), (d), (except that paragraph (d...

  2. 24 CFR 248.175 - Resident homeownership program-limited equity cooperative.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...)), (m) and (n). (c) The purchase and operation of eligible low income housing by a limited equity... carried out in accordance with the provisions of § 248.173 (a), (b), (c), (d), (except that paragraph (d...

  3. 24 CFR 248.175 - Resident homeownership program-limited equity cooperative.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...)), (m) and (n). (c) The purchase and operation of eligible low income housing by a limited equity... carried out in accordance with the provisions of § 248.173 (a), (b), (c), (d), (except that paragraph (d...

  4. 24 CFR 248.121 - Annual authorized return and aggregate preservation rents.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... rehabilitation and energy improvements. For purposes of comparison to the gross rents used in determining the... for the purposes of comparison with the Federal cost limit under § 248.123. Actual rents received by...

  5. 24 CFR 248.121 - Annual authorized return and aggregate preservation rents.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... rehabilitation and energy improvements. For purposes of comparison to the gross rents used in determining the... for the purposes of comparison with the Federal cost limit under § 248.123. Actual rents received by...

  6. 24 CFR 248.121 - Annual authorized return and aggregate preservation rents.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... rehabilitation and energy improvements. For purposes of comparison to the gross rents used in determining the... for the purposes of comparison with the Federal cost limit under § 248.123. Actual rents received by...

  7. 24 CFR 248.121 - Annual authorized return and aggregate preservation rents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... rehabilitation and energy improvements. For purposes of comparison to the gross rents used in determining the... for the purposes of comparison with the Federal cost limit under § 248.123. Actual rents received by...

  8. 17 CFR 248.5 - Annual privacy notice to customers required.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.5 Annual privacy notice to...

  9. 17 CFR 248.5 - Annual privacy notice to customers required.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.5 Annual privacy notice to...

  10. 17 CFR 248.5 - Annual privacy notice to customers required.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.5 Annual privacy notice...

  11. 17 CFR 248.5 - Annual privacy notice to customers required.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.5 Annual privacy notice to...

  12. 17 CFR 248.16 - Protection of Fair Credit Reporting Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Relation to Other Laws; Effective Date § 248.16 Protection of Fair...

  13. 17 CFR 248.16 - Protection of Fair Credit Reporting Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Relation to Other Laws; Effective Date § 248.16 Protection of Fair...

  14. Possibility of using Curium-248 for the development of the reference neutron sources

    SciTech Connect

    Alexandrov, B.M.; Batenkov, O.I.; Blinov, M.V.

    1993-12-31

    Neutron sources on the base of {sup 252}Cf spontaneous fission are widely used. They have great specific neutron yields and comparative low gamma-ray background. But their half-lifes are rather short. The spectrum of {sup 252}Cf spontaneous fission neutrons was recommended by IAEA as an international standard spectrum. {sup 248}Cm is of special interest for a preparation on its base long-lived reference neutron sources. On the one hand its half-life (3.5 10{sup 5} years) is essentially greater than that of {sup 252}Cf (2.7 years), and on the other hand the intensity of {sup 248}Cm spontaneous fission is high enough (10{sup 4} fiss/mg s) which enables to use it in various scientific and practical purposes. For {sup 248}Cm there is practically information only about the middle energy of the spectrum. In this report the {sup 248}Cm spontaneous fission neutron spectrum measurement results are presented for the determination of the possibility of the use of this isotope as international standard and for purposes of a development of reference long-lived neutron sources on {sup 248}Cm base.

  15. The preparation of 248CmF 3 deposits on self-supported carbon foils

    NASA Astrophysics Data System (ADS)

    Aaron, W. S.; Petek, M.; Zevenbergen, L. A.

    1987-06-01

    Another target preparative technique was recently added to the Isotope Research Materials Laboratory's (IRML) capabilities for custom target fabrication. In support of super-heavy-ion physics experiments, methods and equipment were developed for the preparation of 248CmF 3 deposits on carbon foils. The starting material was obtained as either a chloride or nitrate solution, converted to the flouride, and evaporated on carbon foil substrates. Deposits ranging from 40 to 570 μg/cm 2 were prepared as a 12-mm-diam spot on 45- to 60-μg/cm 2 self-supported carbon foils. The deposits were then overcoated with approximately 10 μg/cm 2 of carbon to minimize contamination problems during target handling. The high cost of 248Cm ($100/μg) and its limited availability were the key constraints in the development of preparative technology beyond the inherent radioactivity of 248Cm.

  16. Atomic Mass and NuclearBinding Energy for Md-248(Mendelevium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Md-248 (Mendelevium, atomic number Z = 101, mass number A = 248).

  17. 24 CFR 248.153 - Incentives to extend low income use.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Incentives to extend low income use... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayments and Plans of Action Under the Low Income Housing Preservation and Resident Homeownership Act of 1990 § 248.153 Incentives to extend low income...

  18. 24 CFR 248.231 - Incentives to extend low income use.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Incentives to extend low income use... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.231 Incentives to extend low income use. The Commissioner may...

  19. 40 CFR 81.248 - Southeastern Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Southeastern Alaska Intrastate Air... Air Quality Control Regions § 81.248 Southeastern Alaska Intrastate Air Quality Control Region. The Southeastern Alaska Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  20. 40 CFR 81.248 - Southeastern Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Southeastern Alaska Intrastate Air... Air Quality Control Regions § 81.248 Southeastern Alaska Intrastate Air Quality Control Region. The Southeastern Alaska Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  1. 40 CFR 81.248 - Southeastern Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Southeastern Alaska Intrastate Air... Air Quality Control Regions § 81.248 Southeastern Alaska Intrastate Air Quality Control Region. The Southeastern Alaska Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  2. 40 CFR 81.248 - Southeastern Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Southeastern Alaska Intrastate Air... Air Quality Control Regions § 81.248 Southeastern Alaska Intrastate Air Quality Control Region. The Southeastern Alaska Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  3. 40 CFR 81.248 - Southeastern Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Southeastern Alaska Intrastate Air... Air Quality Control Regions § 81.248 Southeastern Alaska Intrastate Air Quality Control Region. The Southeastern Alaska Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

  4. 24 CFR 248.405 - Grants for building resident capacity and funding predevelopment costs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Technical Assistance and Capacity Building § 248.405 Grants for building resident capacity and funding... assistance grants to resident organizations and community-based nonprofit housing developers and resident... development, legal and other technical assistance to the board of directors, staff and members of the...

  5. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Contents of opt out notice... Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt out... notice; and (vii) A reasonable and simple method for the consumer to opt out. (2) Joint relationships. (i...

  6. 17 CFR 248.13 - Exception to opt out requirements for service providers and joint marketing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exception to opt out... Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.13 Exception to opt out requirements for service providers and joint marketing. (a) General rule. (1) The opt out...

  7. 17 CFR 248.2 - Model privacy form: rule of construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Model privacy form: rule of... Safeguarding Personal Information § 248.2 Model privacy form: rule of construction. (a) Model privacy form. Use of the model privacy form in Appendix A to Subpart A of this part, consistent with the instructions...

  8. 24 CFR 248.233 - Approval of a plan of action that includes incentives.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HOUSING ACT AND OTHER AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of 1987 § 248.233 Approval of a plan of action...— (1) The housing will be retained as housing affordable for very low income families,...

  9. 48 CFR 52.248-2 - Value Engineering-Architect-Engineer.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Value Engineering... Clauses 52.248-2 Value Engineering—Architect-Engineer. As prescribed in 48.201(f), insert the following clause: Value Engineering—Architect-Engineer (MAR 1990) (a) General. The Contractor shall (1) perform...

  10. 12 CFR 303.248 - Truth in Lending Act-Relief from reimbursement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Truth in Lending Act-Relief from reimbursement... PRACTICE FILING PROCEDURES Other Filings § 303.248 Truth in Lending Act—Relief from reimbursement. (a) Scope. This section applies to requests for relief from reimbursement pursuant to the Truth in...

  11. 24 CFR 248.161 - Mandatory sale of housing in excess of the Federal cost limit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... relevant local market in which the project is located by the number of units in the project, according to... transfer preservation value of the project, as determined under § 248.111, the owner shall be obligated to... to purchase the project for a sale price less than the transfer preservation value of the project...

  12. 24 CFR 248.161 - Mandatory sale of housing in excess of the Federal cost limit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., other than paragraphs (a) and (p) of this section thereof, shall be applicable to any sale conducted... transfer preservation value of the project, as determined under § 248.111, the owner shall be obligated to... to purchase the project for a sale price less than the transfer preservation value of the project...

  13. 17 CFR 248.122 - Scope and duration of opt out.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.122 Scope and... information received from another affiliate as described in the notice to make marketing solicitations to the consumer. (2) Continuing relationship—(i) In general. If the consumer establishes a continuing...

  14. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1) In general....

  15. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1) In general....

  16. 17 CFR 248.121 - Affiliate marketing opt out and exceptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Affiliate marketing opt out... COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing § 248.121 Affiliate marketing opt out and exceptions. (a) Initial notice and opt out requirement—(1)...

  17. 9 CFR 354.248 - Scope and applicability of rules of practice.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Maintenance of Sanitary Conditions and Precautions Against Contamination of Products § 354.248 Scope and... I, subtitle A, title 7 of the Code of Federal Regulations, are the rules of practice applicable to adjudicatory, administrative proceedings under the regulations in this part (9 CFR part 354)....

  18. 17 CFR 248.16 - Protection of Fair Credit Reporting Act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Protection of Fair Credit... Safeguarding Personal Information Relation to Other Laws; Effective Date § 248.16 Protection of Fair Credit... the Fair Credit Reporting Act (15 U.S.C. 1681 et seq.), and no inference shall be drawn on the basis...

  19. 17 CFR 248.16 - Protection of Fair Credit Reporting Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Protection of Fair Credit... Safeguarding Personal Information Relation to Other Laws; Effective Date § 248.16 Protection of Fair Credit... the Fair Credit Reporting Act (15 U.S.C. 1681 et seq.), and no inference shall be drawn on the basis...

  20. 17 CFR 248.16 - Protection of Fair Credit Reporting Act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Protection of Fair Credit... Safeguarding Personal Information Relation to Other Laws; Effective Date § 248.16 Protection of Fair Credit... the Fair Credit Reporting Act (15 U.S.C. 1681 et seq.), and no inference shall be drawn on the basis...

  1. 17 CFR 248.2 - Model privacy form: rule of construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information § 248.2 Model privacy form: rule of construction. (a) Model privacy form. Use... CFTC financial privacy rules by futures commission merchants and introducing brokers. Except...

  2. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt... the right to disclose nonpublic personal information about your consumer to a nonaffiliated...

  3. 17 CFR 248.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.9 Delivering privacy and opt out notices... notice as a necessary step to obtaining a particular financial product or service; or (iv) For...

  4. 17 CFR 248.4 - Initial privacy notice to consumers required.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.4 Initial privacy notice... paragraph (e) of this section; and (2) Consumer. A consumer, before you disclose any nonpublic...

  5. 17 CFR 248.6 - Information to be included in privacy notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.6 Information to be included in privacy... to provide: (1) The categories of nonpublic personal information that you collect; (2) The...

  6. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt... the right to disclose nonpublic personal information about your consumer to a nonaffiliated...

  7. 17 CFR 248.2 - Model privacy form: rule of construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information § 248.2 Model privacy form: rule of construction. (a) Model privacy form. Use... CFTC financial privacy rules by futures commission merchants and introducing brokers. Except...

  8. 17 CFR 248.2 - Model privacy form: rule of construction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information § 248.2 Model privacy form: rule of construction. (a) Model privacy form. Use... CFTC financial privacy rules by futures commission merchants and introducing brokers. Except...

  9. 17 CFR 248.6 - Information to be included in privacy notices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.6 Information to be included in privacy... to provide: (1) The categories of nonpublic personal information that you collect; (2) The...

  10. 17 CFR 248.11 - Limits on redisclosure and reuse of information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Limits on Disclosures § 248.11 Limits on redisclosure and reuse of information. (a)(1) Information you receive under an exception. If you receive nonpublic personal...

  11. 17 CFR 248.4 - Initial privacy notice to consumers required.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.4 Initial privacy notice to consumers... section; and (2) Consumer. A consumer, before you disclose any nonpublic personal information about...

  12. 17 CFR 248.15 - Other exceptions to notice and opt out requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.15 Other exceptions to notice and opt out requirements. (a... providers and joint marketing do not apply when you disclose nonpublic personal information: (1) With...

  13. 17 CFR 248.4 - Initial privacy notice to consumers required.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.4 Initial privacy notice to consumers... section; and (2) Consumer. A consumer, before you disclose any nonpublic personal information about...

  14. 17 CFR 248.6 - Information to be included in privacy notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.6 Information to be included in privacy... personal information that you collect; (2) The categories of nonpublic personal information that...

  15. 17 CFR 248.11 - Limits on redisclosure and reuse of information.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Limits on Disclosures § 248.11 Limits on redisclosure and reuse of information. (a)(1) Information you receive under an exception. If you receive nonpublic personal...

  16. 17 CFR 248.4 - Initial privacy notice to consumers required.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.4 Initial privacy notice to consumers... section; and (2) Consumer. A consumer, before you disclose any nonpublic personal information about...

  17. 17 CFR 248.2 - Model privacy form: rule of construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information § 248.2 Model privacy form: rule of construction. (a) Model privacy form. Use... CFTC financial privacy rules by futures commission merchants and introducing brokers. Except...

  18. 17 CFR 248.6 - Information to be included in privacy notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.6 Information to be included in privacy... to provide: (1) The categories of nonpublic personal information that you collect; (2) The...

  19. 17 CFR 248.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-P: Privacy of Consumer Financial Information and Safeguarding Personal Information Privacy and Opt Out Notices § 248.9 Delivering privacy and opt out notices... notice as a necessary step to obtaining a particular financial product or service; or (iv) For...

  20. 17 CFR 248.6 - Information to be included in privacy notices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... companies; and (iii) Others. (4) Disclosures under exception for service providers and joint marketers. If... you and another financial institution; or (B) A financial institution with which you have a joint... currently disclose, nonpublic personal information. (f) Model privacy form. Pursuant to § 248.2(a)...

  1. PCR-RFLP to Detect Codon 248 Mutation in Exon 7 of "p53" Tumor Suppressor Gene

    ERIC Educational Resources Information Center

    Ouyang, Liming; Ge, Chongtao; Wu, Haizhen; Li, Suxia; Zhang, Huizhan

    2009-01-01

    Individual genome DNA was extracted fast from oral swab and followed up with PCR specific for codon 248 of "p53" tumor suppressor gene. "Msp"I restriction mapping showed the G-C mutation in codon 248, which closely relates to cancer susceptibility. Students learn the concepts, detection techniques, and research significance of point mutations or…

  2. PCR-RFLP to Detect Codon 248 Mutation in Exon 7 of "p53" Tumor Suppressor Gene

    ERIC Educational Resources Information Center

    Ouyang, Liming; Ge, Chongtao; Wu, Haizhen; Li, Suxia; Zhang, Huizhan

    2009-01-01

    Individual genome DNA was extracted fast from oral swab and followed up with PCR specific for codon 248 of "p53" tumor suppressor gene. "Msp"I restriction mapping showed the G-C mutation in codon 248, which closely relates to cancer susceptibility. Students learn the concepts, detection techniques, and research significance of point mutations or…

  3. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  4. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  5. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  6. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  7. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  8. 24 CFR 248.221 - Approval of a plan of action that involves termination of low income affordability restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... involves termination of low income affordability restrictions. 248.221 Section 248.221 Housing and Urban... LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayment and Plans of Action Under the Emergency Low Income Preservation Act of...

  9. Stable formation of ultrahigh power-density 248 nm channels in Xe cluster targets

    SciTech Connect

    Borisov, Alex B.; Racz, Ervin; Khan, Shahab F.; Poopalasingam, Sankar; McCorkindale, John C.; Boguta, John; Longworth, James W.; Rhodes, Charles K.

    2012-07-11

    The optimization of relativistic and ponderomotive self-channeling of ultra-powerful 248 nm laser pulses launched in underdense plasmas with an appropriate longitudinal gradient in the electron density profile located at the initial stage of the self-channeling leads to (1) stable channel formation and (2) highly efficient power compression producing power densities in the 10{sup 19}-10{sup 20} W/cm{sup 3} range. The comparison of theoretical studies with experimental results involving the correlation of (a) Thomson images of the electron density with (b) x-ray images of the channel morphology demonstrates that more than 90% of the incident 248 nm power can be trapped in stable channels and that this stable propagation can be extended to power levels significantly exceeding the critical power of the self-channeling process.

  10. Quantum yield for carbon monoxide production in the 248 nm photodissociation of carbonyl sulfide (OCS)

    NASA Astrophysics Data System (ADS)

    Zhao, Z.; Stickel, R. E.; Wine, P. H.

    1995-03-01

    Tunable diode laser absorption spectroscopy has been coupled with excimer laser flash photolysis to measure the quantum yield for CO production from 248 nm photo-dissociation of carbonyl sulfide (OCS) relative to the well-known quantum yield for CO production from 248 nm photolysis of phosgene (Cl2CO). The temporal resolution of the experiments was sufficient to distinguish CO formed directly by photodissociation from that formed by subsequent S(³PJ) reaction with OCS. Under the experimental conditions employed, CO formation via the fast S(¹D2) + OCS reaction was minimal. Measurements at 297K and total pressures from 4 to 100 Torr N2 + N2O show the CO yield to be greater than 0.95 and most likely unity. This result suggests that the contribution of OCS as a precursor to the lower stratospheric sulfate aerosol layer is somewhat larger than previously thought.

  11. Quantum yield for carbon monoxide production in the 248 nm photodissociation of carbonyl sulfide (OCS)

    NASA Technical Reports Server (NTRS)

    Zhao, Z.; Stickel, R. E.; Wine, P. H.

    1995-01-01

    Tunable diode laser absorption spectroscopy has been coupled with excimer laser flash photolysis to measure the quantum yield for CO production from 248 nm photodissociation of carbonyl sulfide (OCS) relative to the well-known quantum yield for CO production from 248 nm photolysis of phosgene (Cl2CO2). The temporal resolution of the experiments was sufficient to distinguish CO formed directly by photodissociation from that formed by subsequent S((sup 3)P(sub J)) reaction with OCS. Under the experimental conditions employed, CO formation via the fast S((sup 1)D(sub 2)) + OCS reaction was minimal. Measurements at 297K and total pressures from 4 to 100 Torr N2 + N2O show the CO yield to be greater than 0.95 and most likely unity. This result suggests that the contribution of OCS as a precursor to the lower stratospheric sulfate aerosol layer is somewhat larger than previously thought.

  12. Quantitative and ultrastructural studies of excimer laser ablation of the cornea at 193 and 248 nanometers

    SciTech Connect

    Puliafito, C.A.; Wong, K.; Steinert, R.F.

    1987-01-01

    Excimer laser radiation at 193 nm and 248 nm was used to create linear etch perforations of enucleated calf corneas. The etch depth per pulse was determined for various exposures, and specimens were examined by light and transmission electron microscopy. Compared to 248 nm, excimer laser ablation at 193 nm was found to have a lower threshold for onset of ablation, less increase in etch depth per pulse at increasing fluences, and less structural alteration in adjacent cornea. For 193 nm, structural alterations were minimal, confined to an area less than 0.3 micron wide, and did not increase with increasing fluence. These studies suggest that clinical strategies for excimer laser refractive surgery will employ the 193-nm wavelength, with fluence chosen depending on surgical strategy. Ablation exposures above 600 mJ/cm2 at 193 nm may give the most repeatable etch depth.

  13. Study on damage of K9 glass under 248nm ultraviolet pulsed laser irradiation

    NASA Astrophysics Data System (ADS)

    Wang, Xi; Fang, Xiaodong

    2015-04-01

    The damage of K9 glass under 248nm ultraviolet pulsed laser irradiation was studied. The laser pulse energy was kept within the range of 60mJ to 160mJ, and the repetition rate was adjusted within the range of 1Hz to 40Hz. The damage morphologies of single-pulse and multi-pulse laser irradiation were characterized by optical microscope, and the damage mechanism was discussed. The experimental results indicated that the damage of K9 glass irradiated by 248nm ultraviolet laser mainly followed the thermal-mechanical coupling mechanism and the damage threshold of K9 glass was 2.8J/cm2. The intensity of damage area increased gradually with the increase of the laser pulse number. It was shown that accumulation effect of laser induced damage to K9 glass was obvious.

  14. Heavy actinide cross sections in the /sup 238/U + /sup 248/Cm reaction

    SciTech Connect

    Kratz, J V; Bruechle, W; Gaeggeler, H

    1981-01-01

    Cross sections for the production of Cf, Es, Fm, and Md isotopes in the reactions of 7.4 MeV/u /sup 238/U-ions with /sup 248/Cm targets are presented and discussed. Cross sections for the formation of heavy actinides in the reactions of 7.5 MeV/u /sup 136/Xe and /sup 238/U-projectiles with /sup 238/U-targets are presented for comparison. (WHK)

  15. Actinide Production in the Reaction of Heavy Ions withCurium-248

    SciTech Connect

    Moody, K.J.

    1983-07-01

    Chemical experiments were performed to examine the usefulness of heavy ion transfer reactions in producing new, neutron-rich actinide nuclides. A general quasi-elastic to deep-inelastic mechanism is proposed, and the utility of this method as opposed to other methods (e.g. complete fusion) is discussed. The relative merits of various techniques of actinide target synthesis are discussed. A description is given of a target system designed to remove the large amounts of heat generated by the passage of a heavy ion beam through matter, thereby maximizing the beam intensity which can be safely used in an experiment. Also described is a general separation scheme for the actinide elements from protactinium (Z = 91) to mendelevium (Z = 101), and fast specific procedures for plutonium, americium and berkelium. The cross sections for the production of several nuclides from the bombardment of {sup 248}Cm with {sup 18}O, {sup 86}Kr and {sup 136}Xe projectiles at several energies near and below the Coulomb barrier were determined. The results are compared with yields from {sup 48}Ca and {sup 238}U bombardments of {sup 248}Cm. Simple extrapolation of the product yields into unknown regions of charge and mass indicates that the use of heavy ion transfer reactions to produce new, neutron-rich above-target species is limited. The substantial production of neutron-rich below-target species, however, indicates that with very heavy ions like {sup 136}Xe and {sup 238}U the new species {sup 248}Am, {sup 249}Am and {sup 247}Pu should be produced with large cross sections from a {sup 248}Cm target. A preliminary, unsuccessful attempt to isolate {sup 247}Pu is outlined. The failure is probably due to the half life of the decay, which is calculated to be less than 3 minutes. The absolute gamma ray intensities from {sup 251}Bk decay, necessary for calculating the {sup 251}Bk cross section, are also determined.

  16. Preparation of /sup 248/CmF/sub 3/ deposits on self-supported carbon foils

    SciTech Connect

    Aaron, W.S.; Petek, M.; Zevenbergen, L.A.

    1986-01-01

    Another target preparative technique was recently added to the Isotope Research Materials Laboratory's (IRML) capabilities for custom target fabrication. In support of super-heavy-ion physics experiments, methods and equipment were developed for the preparation of /sup 248/CmF/sub 3/ deposits on carbon foils. The starting material was obtained as either a chloride or nitrate solution, converted to the fluoride, and evaporated on carbon foil substrates. Deposits ranging from 40 to 570 ..mu..g/cm/sup 2/ were prepared as a 12-mm-diam spot on 45- to 60-..mu..g/cm/sup 2/ self-supported carbon foils. The deposits were then overcoated with approximately 10 ..mu..g/cm/sup 2/ of carbon to minimize contamination problems during target handling. The high cost of /sup 248/Cm ($100/..mu..g) and its limited availability were the key constraints in the development of preparative technology beyond the inherent radioactivity of /sup 248/Cm. 2 refs., 8 figs.

  17. SULFUR- AND SILICON-BEARING MOLECULES IN PLANETARY NEBULAE: THE CASE OF M2-48

    SciTech Connect

    Edwards, J. L.; Ziurys, L. M.

    2014-10-20

    Molecular-line observations of the bipolar planetary nebula (PN) M2-48 have been conducted using the Sub-Millimeter Telescope and the 12 m antenna of the Arizona Radio Observatory at 1, 2, and 3 mm. M2-48 is estimated to be ∼4800 yr old, midway through the PN evolutionary track. SiO and SO{sub 2} were detected in this source—the first identification of either molecule in a PN. CN, HCN, HNC, CS, SO, HCO{sup +}, N{sub 2}H{sup +}, and several {sup 13}C isotopologues such as {sup 13}CN, H{sup 13}CN, and H{sup 13}CO{sup +} were also observed toward this object. A radiative transfer analysis of multiple SiO transitions indicates a gas kinetic temperature of T {sub K} ∼ 55 K and a density of n(H{sub 2}) ∼ 9 × 10{sup 5} cm{sup –3} in M2-48, in agreement with previous CS and CO modeling. After CO, CN, and SO were found to be the most prevalent molecules in this nebula, with fractional abundances, relative to H{sub 2}, of f ∼ 3.8 × 10{sup –7} and 2.4 × 10{sup –7}, respectively. SO{sub 2} and HCN are also abundant, with f ∼ 1.2 × 10{sup –7}, indicating an [SO]/[SO{sub 2}] ratio of ∼2. Relatively high ion abundances were measured in M2-48 as well, with f ∼ 10{sup –7} for both HCO{sup +} and N{sub 2}H{sup +}. An [HCN]/[HNC] ratio of ∼2 was determined, as typically observed in other PNe, independent of age. The high abundances of SO and SO{sub 2}, along with the presence of SiO with f ∼ 2.9 × 10{sup –8}, suggest O/C > 1 in this source; furthermore, the prevalence of CN and N{sub 2}H{sup +} indicates nitrogen enrichment. The {sup 12}C/{sup 13}C ratio of ∼3 in the nebula was also established. These factors indicate hot-bottom burning occurred in the progenitor star of M2-48, suggesting an initial mass > 4 M {sub ☉}.

  18. 42 CFR 137.248 - What effect will a retrocession have on a retroceding Self-Governance Tribe's rights to contract...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... retroceding Self-Governance Tribe's rights to contract or compact under the Act? 137.248 Section 137.248 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.248 What effect will a...

  19. Spatial structure of oligopeptide PAP(248-261), the N-terminal fragment of the HIV enhancer prostatic acid phosphatase peptide PAP(248-286), in aqueous and SDS micelle solutions

    NASA Astrophysics Data System (ADS)

    Blokhin, Dmitriy S.; Filippov, Andrei V.; Antzutkin, Oleg N.; Karataeva, Farida Kh.; Klochkov, Vladimir V.

    2014-07-01

    Prostatic acid phosphatase (PAP) is an enzyme that facilitates infection of cells by HIV. Its peptide fragment PAP(248-286) forms amyloid fibrils known as SEVI, which enhance attachment of the virus by viral adhesion to the host cell prior to receptor-specific binding via reducing the electrostatic repulsion between the membranes of the virus and the target cell. The secondary structure of PAP(248-286) in aqueous and SDS solutions can be divided into an N-terminal disordered region, an α-helical central part and an α/310-helical C-terminal region (Nanga et al., 2009). In this work, we used NMR spectroscopy to study the spatial structure of the isolated N-terminal fragment of PAP(248-286), PAP(248-261) (GIHKQKEKSRLQGG), in aqueous and SDS micelle solutions. Formation of a PAP(248-261)-SDS complex was confirmed by chemical shift alterations in the 1H NMR spectra of the peptide, as well as by the signs and values of Nuclear Overhauser Effect (NOE). In addition, the PAP(248-261) peptide does not form any specified secondary structure in either aqueous or SDS solutions.

  20. Production of cold target-like fragments in the reaction of /sup 48/Ca+/sup 248/Cm

    SciTech Connect

    Gaeggeler, H.; Bruechle, W.; Bruegger, M.; Schaedel, M.; Suemmerer, K.; Wirth, G.; Kratz, J.V.; Lerch, M.; Blaich, T.; Herrmann, G.

    1986-06-01

    Yields for isotopes of Rn through Pu have been measured in the reaction /sup 48/Ca+/sup 248/Cm at an energy of 248--263 MeV (1.04--1.10 times the Coulomb barrier). Despite the low bombarding energy, high and essentially constant integral yields of about 1 to 2 mb for the elements Rn through U were observed. There is evidence that these nuclides are produced with little excitation energy.

  1. Comparison of acid-generating efficiencies in 248 and 193-nm photoresists

    NASA Astrophysics Data System (ADS)

    Cameron, James F.; Chan, Nicholas; Moore, Kathryn; Pohlers, Gerd

    2001-08-01

    Photoacid generation is a critical step in the application of chemically amplified (CA) resist technology. During the key exposure step, a catalytic amount of a strong Bronsted acid is released within these resists. The photoacid is subsequently used in a post-exposure bake step to catalytically react with the resist polymer. In the case of a positive tone resist, an acid sensitive polymer is deprotected to render the exposed areas soluble in dilute aqueous base thereby allowing for pattern development. As the semicondutor industry beings to focus on developing 193 nm photoresists for production, it si important to identify and understand differences between prototype 193nm CA resists and current state of the art 248nm production worth photoresists. The major difference between 193 and 248 nm photoresists is the exposure wavelength, which isr educed to achieve higher resolution based on the Rayleigh equation. However, this change in wavelength has several ramifications: Firstly, the tried, tested and true phenolic polymers used in DUV resists are too absorbent to be used fo 193nm application and had to be replaced by low absorbing, non-aromatic systems. Second, since even these new platforms are still more absorbing at 193 nm than the phenolic matrices are at 248nm, the PAG loading had to be lowered significantly in order to keep the overall absorbance of the resist down. This paper descibes the results of our systematic studies on understanding the reasons for observed differences in photoacid generating efficincy between 193 and 248nm chemically amplified resist systems. First the wavelength effect is studied by comparing the relative acid generating efficiency of onium type PAGs in a prototype 193nm and a DUV photoresist at both 193 nm and 248 nm exposure. Second, the photoacid generating efficiency for these PAGs at 238 nm is compared in both phenolic and non-phenolic based photoresists to probe resist polymer matrix effects. Third, these experiments were

  2. The amyloidogenic SEVI precursor, PAP248-286, is highly unfolded in solution despite an underlying helical tendency

    PubMed Central

    Brender, Jeffrey R.; Nanga, Ravi Prakash Reddy; Popovych, Nataliya; Soong, Ronald; Macdonald, Peter M.; Ramamoorthy, Ayyalusamy

    2011-01-01

    Amyloid fibers in human semen known as SEVI (Semen-derived Enhancer of Viral Infection) dramatically increase the infectivity of HIV and other enveloped viruses, which appears to be linked to the promotion of bridging interactions and the neutralization of electrostatic repulsion between the host and the viral cell membranes. The SEVI precursor PAP248-286 is mostly disordered when bound to detergent micelles, in contrast to the highly α-helical structures found for most amyloid proteins. To determine the origin of this difference, the structures of PAP248-286 were solved in aqueous solution and with 30% and 50% trifluoroethanol. In solution, pulsed field gradient (PFG)-NMR and 1H-1H NOESY experiments indicate that PAP248-286 is unfolded to an unusual degree for an amyloidogenic peptide but adopts significantly helical structures in TFE solutions. The clear differences between the structures of PAP248-286 in TFE and SDS indicate electrostatic interactions play a large role in the folding of the peptide, consistent with the slight degree of penetration of PAP248-286 into the hydrophobic core of the micelle. This is another noticeable difference between PAP248-286 and other amyloid peptides, which generally show penetration into at least the headgroup region of the bilayer, and may explain some of the unusual properties of SEVI. PMID:21262195

  3. SN Hunt 248: a super-Eddington outburst from a massive cool hypergiant

    NASA Astrophysics Data System (ADS)

    Mauerhan, Jon C.; Van Dyk, Schuyler D.; Graham, Melissa L.; Zheng, WeiKang; Clubb, Kelsey I.; Filippenko, Alexei V.; Valenti, Stefano; Brown, Peter; Smith, Nathan; Howell, D. Andrew; Arcavi, Iair

    2015-02-01

    We present observations of SN Hunt 248, a new supernova (SN) impostor in NGC 5806, which began a multistage outburst in 2014 May. The `2014a' discovery brightening exhibited an absolute magnitude of M ≈ -12 and the spectral characteristics of a cool, dense outflow, including P Cygni lines of Fe II, H I, and Na I, and line blanketing from metals. The source rapidly climbed and peaked at M ≈ -15 mag after two additional weeks. During this bright `2014b' phase the spectrum became dominated by Balmer emission and a stronger blue continuum, similar to the SN impostor SN 1997bs. Archival images from the Hubble Space Telescope between 1997 and 2005 reveal a luminous (4 × 105 L⊙) variable precursor star. Its location on the Hertzsprung-Russell diagram is consistent with a massive (Minit ≈ 30 M⊙) cool hypergiant having an extremely dense wind and an Eddington ratio (Γ) just below unity. At the onset of the 2014a brightening, however, the object was super-Eddington (Γ = 4-12). The subsequent boost in luminosity during the 2014b phase probably resulted from circumstellar interaction. SN Hunt 248 provides the first case of a cool hypergiant undergoing a giant eruption reminiscent of outbursts from luminous blue variable stars (LBVs). This lends support to the hypothesis that some cool hypergiants, such as ρ Cas, could be LBVs masquerading under a pseudo-photosphere created by their extremely dense winds. Moreover, SN Hunt 248 demonstrates that eruptions stemming from such stars can rival in peak luminosity the giant outbursts of much more massive systems like η Car.

  4. Laser-damage processes in cleaved and polished CaF{sub 2} at 248nm

    SciTech Connect

    Reichling, M.; Gogoll, S.; Stenzel, S.

    1996-12-31

    Single-shot irradiation of single crystal CaF{sub 2} with 248nm/14ns laser light results in various degrees of degradation and damage depending on the applied laser fluence. Phenomena range from subtle, non-topographic surface modification only detectable by secondary electrons of scanning electron microscopy (SE-SEM) over cracking along crystallographic directions to the ablation of crystalline material. Significant differences are found for cleaved and polished surfaces. Findings from SEM investigations, in-situ photoacoustic mirage measurements and visual inspection of irradiated samples form a comprehensive picture of the stages of laser-induced damage.

  5. Laser holographic nondestructive testing of the NASA X-248 rocket motor

    NASA Technical Reports Server (NTRS)

    Harris, W. J.

    1973-01-01

    A program to apply holography for nondestructive testing of the X-248 rocket motor was undertaken. The objective was to establish the capability of holography in detecting known unbonding between liner and propellant. Holography was performed employing stressing techniques: (1) acoustical, (2) thermal, (3) radiative, and (4) static loading. Radiative stressing was successful in locating a large area of liner/propellant unbond. The results were correlated with destructive testing. Theoretical analysis provided an understanding of motor case holography in conjunction with radiative stressing.

  6. Ion imaging studies of the photodissociation dynamics of CH2I2 at 248 nm

    NASA Astrophysics Data System (ADS)

    Lehman, Julia H.; Li, Hongwei; Lester, Marsha I.

    2013-12-01

    The photodissociation of CH2I2 at 248 nm is investigated using velocity map ion imaging with photoionization detection of the I∗ (2P1/2) products. The velocity distribution of the I∗ products reveals that only a small fraction of the available energy is released as translational energy, consistent with a simple impulsive model. Most of the excess energy is channeled into internal excitation with = 36.3 kcal mol-1 for CH2I radical fragments produced with I∗ atoms. The anisotropy angular distribution of the I∗ fragments and corresponding positive anisotropy parameter are indicative of prompt dissociation and electronic state mixing.

  7. Damage thresholds of thin film materials and high reflectors at 248 nm

    SciTech Connect

    Rainer, F.; Lowdermilk, W.H.; Milam, D.; Carniglia, C.K.; Hart, T.T.; Lichtenstein, T.L.

    1982-01-01

    Twenty-ns, 248-nm KrF laser pulses were used to measure laser damage thresholds for halfwave-thick layers of 15 oxide and fluoride coating materials, and for high reflectance coatings made with 13 combinations of these materials. The damage thresholds of the reflectors and single-layer films were compared to measurements of several properties of the halfwave-thick films to determine whether measurements of these properties of single-layer films to determine whether measurements of these properties of single-layer films were useful for identifying materials for fabrication of damage resistant coatings.

  8. A novel approach to developer-soluble anti-reflective coatings for 248-nm lithography

    NASA Astrophysics Data System (ADS)

    Mercado, Ramil-Marcelo L.; Lowes, Joyce A.; Washburn, Carlton A.; Guerrero, Douglas J.

    2007-03-01

    A novel approach to developer-soluble bottom anti-reflective coatings (BARCs) for 248-nm lithography was demonstrated. The BARC formulations are photosensitive, dye-filled systems incorporated with a polymer binder. The films are generated by thermally crosslinking the polymer matrix, and are then photochemically decrosslinked in order to render them soluble in developer solutions. The BARCs are compatible with solvents commonly used in the industry. Easy modification of the films with regard to optical properties for potential use with various substrates was also demonstrated. The BARCs exhibit anisotropic development in aqueous tetramethylammonium hydroxide (TMAH) solutions subsequent to simulated photoresist application, exposure, and post-exposure bake.

  9. Fermi LAT detection of increase gamma-ray emission from OJ 248

    NASA Astrophysics Data System (ADS)

    Orienti, M.; D'Ammando, F.

    2012-09-01

    The Large Area Telescope (LAT), on board the Fermi Gamma-ray Space Telescope, has observed gamma-ray flaring activity from a source positionally consistent with the flat spectrum radio quasar OJ 248 (also known as 2FGL J0830.5+2407, Nolan et al. 2012, ApJS, 199, 31) with radio coordinates R.A.: 127.7170254 deg, Dec: 24.1832836 deg (J2000, Johnston et al. 1995, AJ, 110, 880) at redshift z=0.94 (Hewitt & Burbidge 1993, ApJS, 87, 451).

  10. Development of damage resistant sputtered oxide optical coatings for use at 248 NM

    SciTech Connect

    Pawlewicz, W.T.; Martin, P.M.; Hays, D.D.; Mann, I.B.

    1981-10-01

    This report summarizes the results of a six-month effort to develop damage-resistant Kr*F laser mirrors by using and refining reactive sputter deposition techniques for the fabricaton of multilayer oxide optical coatings. Mirror performance goals included a reflectivity of 99% at 248 nm and a laser damage threshold of 5 J/cm/sup 2/ for 20 ns pulses. Oxide multilayer coating combinations selected for development were SiO/sub 2//Al/sub 2/O/sub 3/, SiO/sub 2//HfO/sub 2/ and SiO/sub 2//Y/sub 2/O/sub 3/. Selection was based on review and compilation of the optical properties of oxide materials reported in the recent literature. Twenty-eight coatings of selected designs were fabricated on LLNL substrates for laser damage testing by LLNL. Forty other coatings were fabricated on PNL substrates for optical, microstructural and topographical characterization by PNL aimed at optimization of their performance. Specimens for damage testing consisted of single layers of Al/sub 2/O/sub 3/, HfO/sub 2/ and Y/sub 2/O/sub 3/ in thicknesses of lambda/2, 3lambda/2 and 2lambda at 248 nm plus high reflectors of the design LL (HL)/sup m/ HLL.

  11. Quantum yield for carbon monoxide production in the 248 nm photodissociation of carbonyl sulfide (OCS)

    SciTech Connect

    Zhao, Z.; Stickel, R.E.; Wine, P.H.

    1995-03-01

    Tunable diode laser absorption spectroscopy has been coupled with excimer laser flash photolysis to measure the quantum yield for CO production from 248 nm photodissociation of carbonyl sulfide (OCS) relative to the well known quantum yield for CO production from 248 nm photolysis of phosgene (Cl{sub 2}CO). The temporal resolution of the experiments was sufficient to distinguish CO formed directly by photodissociation from that formed by subsequent S({sup 3}P{sub j}) reaction with OCS. Under the experimental conditions employed, CO formation via the fast S({sup 1}D{sub 2})+OCS reaction was minimal. Measurements at 297K and total pressures from 4 to 100 Torr N{sub 2}+N{sub 2}O show the CO yield to be greater than 0.95 and most likely unity. This result suggests that the contribution of OCS as a precursor to the lower stratospheric sulfate aerosol layer is somewhat larger than previously thought. 25 refs., 1 fig., 2 tabs.

  12. Actinide production in the reaction of heavy ions with curium-248

    SciTech Connect

    Moody, K.J.

    1983-01-01

    Chemical experiments were performed to examine the usefulness of heavy ion transfer reactions in producing new, neutron-rich actinide nuclides. A general quasi-elastic to deep-inelastic mechanism is proposed, and the utility of this method as opposed to other methods (e.g. complete fusion) is discussed. The relative merits of various techniques of actinide target synthesis are discussed. A description is given of a target system designed to remove the large amounts of heat generated by the passage of a heavy ion beam through matter, thereby maximizing the beam intensity which can be safely used in an experiment. Also described is a general separation scheme for the actinide elements from protactinium (Z = 91) to mendelevium (Z = 101), and fast specific procedures for plutonium, americium and berkelium. The cross sections for the production of several nuclides from the bombardment of /sup 248/Cm with /sup 18/Kr and /sup 86/O, /sup 136/Xe projectiles at several energies near and below the Coulomb barrier were determined. The results are compared with yields from /sup 48/Ca and /sup 238/U bombardments of /sup 248/Cm. A preliminary, unsuccessful attempt to isolate /sup 247/Pu is outlined. The absolute ..gamma.. ray intensities from /sup 251/Bk decay, necessary for calculating the /sup 251/Bk cross section, are also determined.

  13. Micromachining of polyurethane (PU) polymer using a KrF excimer laser (248 nm)

    NASA Astrophysics Data System (ADS)

    Singh, Sarabpreet; Sharma, Sunil

    2014-12-01

    Polyurethane (PU) polymer, due to its biocompatibility, weather resistance, and favorable physical properties, finds a number of applications in medical implants, protective coatings, and as a prototype material for structural components in MEMS devices. An excimer laser (wavelength = 248 nm, FWHM = 25 ns) is employed for micromachining of polyurethane (PU) polymer. For air environment, the ablation rate is 0.18 μm/pulse and for underwater environment, the ablation rate is 0.07 μm/pulse (with underwater ablation threshold as 0.10 J/cm2), which concluded low taper angles (∼32°) for in air as compared to high taper angles (∼65°) with underwater micromachining. The experimental results for air and under water micromachining demonstrate ablation process as a combination of photo-thermal and photo-chemical mechanism.

  14. Study of 242-248Cm isotopes in the projected shell model framework

    NASA Astrophysics Data System (ADS)

    Sadiq, Saiqa; Devi, Rani; Khosa, S. K.

    2016-04-01

    The projected shell model framework is employed to study the band spectra in 242-248Cm isotopes. The present calculations reproduce the available experimental data on the yrast bands. Besides this, B(E2) transition probabilities of even-even Cm isotopes have also been calculated. The low spin states of yrast band are seen to arise purely from zero-quasi-particle (o-qp) intrinsic states whereas the high spin states have multi-quasi-particle structure. For the odd-neutron (odd-N) isotopes, the calculated results qualitatively reproduce the available data on ground and lowest excited state bands for 243,245Cm. However, for 247Cm the negative-parity ground state band is in reasonable agreement with the experimental data.

  15. Molecular growth from a Mo176 to a Mo248 cluster

    NASA Astrophysics Data System (ADS)

    Müller, A.; Shah, Syed Q. N.; Bögge, H.; Schmidtmann, M.

    1999-01-01

    In polyoxometalate chemistry a large variety of compounds, clusters and solid-state structures can be formed by the linking together of well-defined metal-oxygen building blocks, . These species exhibit unusual topological and electronic properties, andfind applications ranging from medicine to industrial processes. The recently reported ring-shaped mixed-valence polyoxomolybdates of the type {Mo154} (refs 5, 6) and {Mo176} (refs 7, 8) represent a new class of giant clusters with nanometre-sized cavities and interesting properties for host-guest chemistry. Here we describe the formation of related clusters of the type {Mo248} formed by addition of further units to the inner surface of the {Mo176 } `wheel'. The additional units arrange themselves into two {Mo36} `hub-caps' on the initial wheel-clusters that are not stable in isolation. These findings reveal a new pathway to the development of complex coordination clusters.

  16. Excitation functions for actinides produced in the interactions of sup 31 P with sup 248 Cm

    SciTech Connect

    Leyba, J.D.; Henderson, R.A.; Hall, H.L.; Czerwinski, K.R.; Kadkhodayan, B.A.; Kreek, S.A.; Brady, E.K.; Gregorich, K.E.; Lee, D.M.; Nurmia, M.J.; Hoffman, D.C. Nuclear Science Division, Lawrence Berkeley Laboratory, University of California, Berkeley, California )

    1991-11-01

    Excitation functions have been measured for the production of various isotopes of Bk, Cf, Es, and Fm from the interactions of 174- and 239-MeV {sup 31}P projectiles with {sup 248}Cm. The isotopic distributions were symmetric and displayed full widths at half maximum of 2.5, 2.5, and 2.25 mass units for Bk, Cf, and Fm, respectively. The maxima of the isotopic distributions occur for those reaction channels which involve the exchange of the fewest number of nucleons between the target and projectile for which the calculated excitation energy is a positive quantity. The maxima of the excitation functions occur at those projectile energies which are consistent with the calculated reaction barriers based upon a binary reaction mechanism. The effects of the odd proton in the {sup 31}P projectile on the final isotopic distributions are discussed.

  17. Photodissociation of pernitric acid (HO2NO2) at 248 nm

    NASA Technical Reports Server (NTRS)

    Macleod, Helene; Smith, Gregory P.; Golden, David M.

    1989-01-01

    The photodissociation of pernitric acid (PNA) was studied at 248 nm. The quantum yield for production of OH radicals is 34 + or - 16 percent. The yield of OH from PNA was measured relative to that of H2O2. The translational and rotational energy content of the OH photofragment from PNA was characterized. A fluorescent emission was also observed and characterized. It is attributed to electronically excited NO2 produced in the PNA photodissociation. A maximum yield of 30 percent for NO2 production was determined. The intensity of this emission, and a mass spectrometric peak at m/e = 33, were found to be useful means of characterizing the purity of the PNA sample.

  18. Genetic testing of 248 Chinese aortopathy patients using a panel assay.

    PubMed

    Yang, Hang; Luo, Mingyao; Fu, Yuanyuan; Cao, Yandong; Yin, Kunlun; Li, Wenke; Meng, Chunjie; Ma, Yanyun; Zhang, Jing; Fan, Yuxin; Shu, Chang; Chang, Qian; Zhou, Zhou

    2016-09-09

    Inherited aortopathy, which is characterized by a high risk of fatal aortic aneurysms/dissections, can occur secondarily to several syndromes. To identify genetic mutations and help make a precise diagnosis, we designed a gene panel containing 15 genes responsible for inherited aortopathy and tested 248 probands with aortic disease or Marfan syndrome. The results showed that 92 individuals (37.1%) tested positive for a (likely) pathogenic mutation, most of which were FBN1 mutations. We found that patients with a FBN1 truncating or splicing mutation were more prone to developing severe aortic disease or valvular disease. To date, this is the largest reported cohort of Chinese patients with aortic disease who have undergone genetic testing. Therefore, it can serve as a considerable dataset of next generation sequencing data analysis of Chinese population with inherited aortopathy. Additionally, according to the accumulated data, we optimized the analysis pipeline by adding quality control steps and lowering the false positive rate.

  19. Genetic testing of 248 Chinese aortopathy patients using a panel assay

    PubMed Central

    Yang, Hang; Luo, Mingyao; Fu, Yuanyuan; Cao, Yandong; Yin, Kunlun; Li, Wenke; Meng, Chunjie; Ma, Yanyun; Zhang, Jing; Fan, Yuxin; Shu, Chang; Chang, Qian; Zhou, Zhou

    2016-01-01

    Inherited aortopathy, which is characterized by a high risk of fatal aortic aneurysms/dissections, can occur secondarily to several syndromes. To identify genetic mutations and help make a precise diagnosis, we designed a gene panel containing 15 genes responsible for inherited aortopathy and tested 248 probands with aortic disease or Marfan syndrome. The results showed that 92 individuals (37.1%) tested positive for a (likely) pathogenic mutation, most of which were FBN1 mutations. We found that patients with a FBN1 truncating or splicing mutation were more prone to developing severe aortic disease or valvular disease. To date, this is the largest reported cohort of Chinese patients with aortic disease who have undergone genetic testing. Therefore, it can serve as a considerable dataset of next generation sequencing data analysis of Chinese population with inherited aortopathy. Additionally, according to the accumulated data, we optimized the analysis pipeline by adding quality control steps and lowering the false positive rate. PMID:27611364

  20. Study of the Reaction 48Ca + 248Cm → 296Lv* at RIKEN-GARIS

    NASA Astrophysics Data System (ADS)

    Kaji, Daiya; Morita, Kosuke; Morimoto, Kouji; Haba, Hiromitsu; Asai, Masato; Fujita, Kunihiro; Gan, Zaiguo; Geissel, Hans; Hasebe, Hiroo; Hofmann, Sigurd; Huang, MingHui; Komori, Yukiko; Ma, Long; Maurer, Joachim; Murakami, Masashi; Takeyama, Mirei; Tokanai, Fuyuki; Tanaka, Taiki; Wakabayashi, Yasuo; Yamaguchi, Takayuki; Yamaki, Sayaka; Yoshida, Atsushi

    2017-03-01

    The fusion reaction 48Ca + 248Cm → 296Lv* was investigated using the gas-filled recoil ion separator GARIS at RIKEN. The reaction was studied at excitation energies of 41.3 and 38.2 MeV. A total of seven decay chains were observed. Three of the chains were assigned to the decay of 292Lv and three to the decay of 293Lv. A possible observation of an α-decay branch of 284Cn populating the new spontaneously fissioning nucleus 280Ds is discussed. The assignment of one of the decay chains to the 3n evaporation channel, resulting in a spontaneous fission branch of 285Cn, or to the 2n channel, resulting in the population of the new fissioning nucleus 286Cn, is ambiguous. Measured cross sections are in agreement with previously published values.

  1. Cross section limits for the Cm248(Mg25,4n-5n)Hs268,269 reactions

    NASA Astrophysics Data System (ADS)

    Dvorak, J.; Brüchle, W.; Düllmann, Ch. E.; Dvorakova, Z.; Eberhardt, K.; Eichler, R.; Jäger, E.; Nagame, Y.; Qin, Z.; Schädel, M.; Schausten, B.; Schimpf, E.; Schuber, R.; Semchenkov, A.; Thörle, P.; Türler, A.; Wegrzecki, M.; Yakushev, A.

    2009-03-01

    We report on an attempt to produce and detect Hs268 and Hs269 in the nuclear fusion reaction Mg25+Cm248 using the gas phase chemistry apparatus COMPACT. No decay chains attributable to the decay of hassium isotopes were observed during the course of this experiment. From the nonobservation of Hs269 we derive a cross section limit of 0.4 pb (63% confidence limit) for the reaction Cm248(Mg25,4n)Hs269 at a center-of-target beam energy of 140 MeV. The evaluated cross section limit for the Cm248(Mg25,5n)Hs268 reaction depends on the assumed half-life of unknown Hs268. Current systematics of the half-lives for even-even Hs isotopes suggests a value of 0.5 s, resulting in a cross section limit of 1.3 pb.

  2. A systematic study of actinide production from the interactions of heavy ions with sup 248 Cm

    SciTech Connect

    Leyba, J.D.

    1990-09-07

    Production cross sections for heavy actinides produced from the interactions of {sup 12}C, {sup 31}P, {sup 40}Ar, and {sup 44}Ca ions with {sup 248}Cm were measured at energies ranging from 0.98 to 1.35 X Coulomb barrier. The recoiling reaction products were collected in copper or gold catcher foils located near the {sup 248}Cm target. Separate fractions of Bk, Cf, Es, Fm, and Md were obtained from a radiochemical separation procedure. For the {sup 12}C system, a He/KCl jet was used to transport the recoiling No activities of interest to a rotating wheel system. The isotopic distributions of the actinide products were found to be essentially symmetric about the maximum with full-widths-at-half-maximum of approximately 2.5 mass units. Isotopic distributions of the {sup 12}C, {sup 31}P, {sup 40}Ar, and {sup 44}Ca systems were found to be very similar to the {sup 40,48}Ca systems studied previously. The maxima of the isotopic distributions generally occurred for those reaction channels which involved the exchange of the fewest number of nucleons between the target and projectile for which the calculated excitation energy was a positive quantity. Additionally, the maxima of the excitation functions occurred at those projectile energies which were consistent with the calculated reaction barriers based upon a binary reaction mechanism. The experimental data from the four systems investigated were compared to several models of heavy ion interactions including a damped reaction mechanism, compound nucleus formation and subsequent particle evaporation, and classical partial wave calculations for binary systems.

  3. The research progress of metrological 248nm deep ultraviolent microscope inspection device

    NASA Astrophysics Data System (ADS)

    Wang, Zhi-xin; Li, Qi; Gao, Si-tian; Shi, Yu-shu; Li, Wei; Li, Shi

    2016-01-01

    In lithography process, the precision of wafer pattern to a large extent depends on the geometric dimensioning and tolerance of photomasks when accuracy of lithography aligner is certain. Since the minimum linewidth (Critical Dimension) of the aligner exposing shrinks to a few tens of nanometers in size, one-tenth of tolerance errors in fabrication may lead to microchip function failure, so it is very important to calibrate these errors of photomasks. Among different error measurement instruments, deep ultraviolent (DUV) microscope because of its high resolution, as well as its advantages compared to scanning probe microscope restrained by measuring range and scanning electron microscope restrained by vacuum environment, makes itself the most suitable apparatus. But currently there is very few DUV microscope adopting 248nm optical system, means it can attain 80nm resolution; furthermore, there is almost no DUV microscope possessing traceable calibration capability. For these reason, the National Institute of Metrology, China is developing a metrological 248nm DUV microscope mainly consists of DUV microscopic components, PZT and air supporting stages as well as interferometer calibration framework. In DUV microscopic component, the Köhler high aperture transmit condenser, DUV splitting optical elements and PMT pinhole scanning elements are built. In PZT and air supporting stages, a novel PZT actuating flexural hinge stage nested separate X, Y direction kinematics and a friction wheel driving long range air supporting stage are researched. In interferometer framework, a heterodyne multi-pass interferometer measures XY axis translation and Z axis rotation through Zerodur mirror mounted on stage. It is expected the apparatus has the capability to calibrate one dimensional linewidths and two dimensional pitches ranging from 200nm to 50μm with expanded uncertainty below 20nm.

  4. Multiple-shot ultraviolet laser damage resistance of nonquarterwave reflector designs for 248 NM

    SciTech Connect

    Newnam, B.E.; Foltyn, S.R.; Jolin, L.J.

    1982-01-01

    The damage resistance of multilayer dielectric reflectors designed for 248 nm has been substantially increased by use of nonquarterwave (QW) thicknesses for the top few layers. These designs minimize the peak standing-wave electric field in the high-index layers, which have proven to be weaker than the low-index components. Previous damage tests of infrared- and visible-wavelength reflectors based on these designs have produced variable results. However, at the ultraviolet wavelength of 248 nm, 99% reflectors of Sc/sub 2/O/sub 3/, MgF/sub 2/, and SiO/sub 2/ strongly demonstrated the merit of non-QW designs. Four sets of reflectors of each of four designs (all QW thickness; one modified-pair substitution; two modified-pair substitution; one modified pair plus an extra half-wave layer of Sc/sub 2/O/sub 3/) were tested for damage resistance with a KrF laser operating at 35 pps with a pulsewidth of 8 ns and spot-size diameter of 0.6 mm. Each of 50 sites were irradiated for 1000 shots or until damage occurred. On the average, the reflectors with one-modified-thickness pair had a 50% higher threshold (10 to 10 sites survived) than the all-quarterwave design. Addition of a second modified-layer pair resulted in no further increase in threshold but the saturation fluence (10 of 10 sites damage) was 110% higher. Reflectors with an additional half-wave of Sc/sub 2/O/sub 3/ had lower thresholds of the order of 10% as expected. The thresholds correlated best with peak-field models, whereas the best model correlating the saturation fluences involved the sum of the upper two scandia layer thicknesses.

  5. Development, inheritance and breeding potential of a recessive genic male sterile line D248A in Sesame (Sesamum indicum L.).

    PubMed

    Liu, Hongyan; Yang, Minmin; Wu, Kun; Zhou, Xinan; Zhao, Yingzhong

    2013-01-01

    Genic male sterility (GMS) has great potential for heterosis exploitation in sesame (Sesamum indicum L.). Two spontaneous male-sterile plants were discovered in a Chinese sesame cultivar (Zhuzhi 4) in 2006. By consecutive sib mating with fertile plants from Zhuzhi 4, a new sterile line, D248A, was developed. Anatomy studies showed that D248A has thin, small and greenish anthers on which there are no or little pollen grains. The pollens are irregularly shaped and completely aborted, resulting in no germination and no formation of pollen tubes as revealed by acetocarmine stain or semi-solid suspension culture. Furthermore, D248A has a better performance in growth vigor, bloom duration and yield per plant than the other GMS lines (i.e. 95 ms-2A and 95 ms-5A). To investigate the inheritance mode of fertility, D248A was crossed and backcrossed with six varieties, and a segregating ratio of 3:1 and 1:1 for fertile and sterile plants was observed in F2 and BC1 populations, respectively. These results suggested that D248A is controlled by a recessive GMS gene. The average yield of four D248A-derived F1 hybrids is as high as 1695 kg·ha(-1), which is almost twice of that of 95 ms-5A-derived F1 hybrids. These results indicated that this newly developed recessive GMS line has great potential in sesame hybrid breeding.

  6. NMR Structure in a Membrane Environment Reveals Putative Amyloidogenic Regions of the SEVI Precursor Peptide PAP248–286

    PubMed Central

    Nanga, Ravi P.; Brender, Jeffrey R.; Vivekanandan, Subramanian; Popovych, Nataliya; Ramamoorthy, Ayyalusamy

    2009-01-01

    Semen is the main vector for HIV transmission worldwide. Recently, a peptide fragment (PAP248–286) has been isolated from seminal fluid that dramatically enhances HIV infectivity by up to four to five orders of magnitude. PAP248–286 appears to enhance HIV infection by forming amyloid fibers known as SEVI, which are believed to enhance the attachment of the virus by bridging interactions between virion and host-cell membranes. We have solved the atomic-level resolution structure of the SEVI precursor PAP248–286 using NMR spectroscopy in SDS micelles, which serve as a model membrane system. PAP248–286, which does not disrupt membranes like most amyloid proteins, binds superficially to the surface of the micelle, in contrast to other membrane-disruptive amyloid peptides that generally penetrate into the core of the membrane. The structure of PAP248–286 is unlike most amyloid peptides in that PAP248–286 is mostly disordered when bound to the surface of the micelle, as opposed to the α-helical structures typically found of most amyloid proteins. The highly disordered nature of the SEVI peptide may explain the unique ability of SEVI amyloid fibers to enhance HIV infection as partially disordered amyloid fibers will have a greater capture radius for the virus than compact amyloid fibers. Two regions of nascent structure (an α-helix from V262-H270 and a dynamic α/310 helix from S279-L283) match the prediction of highly amyloidogenic sequences and may serve as nuclei for aggregation and amyloid fibril formation. The structure presented here can be used for the rational design of mutagenesis studies on SEVI amyloid formation and viral infection enhancement. PMID:19995078

  7. EPAs $2.48 million grant will support efforts to improve air quality, protect people, in Idahos West Silver Valley

    EPA Pesticide Factsheets

    (Seattle, WA - October 22, 2015) The Idaho Department of Environmental Quality has received a $2.48 million EPA grant to reduce pollution and protect air quality in northern Idaho's West Silver Valley. The grant is part of EPA's 2015 Targeted Air Shed Gran

  8. 77 FR 12365 - Agency Information Collection; Activity Under OMB Review: Submission of Audit Reports-Part 248

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ...: Submission of Audit Reports--Part 248 AGENCY: Research and Innovative Technology Administration (RITA... requiring U.S. large certificated air carriers to submit two true and complete copies of its annual audit that is made by an independent public accountant. If a carrier does not have an annual audit,...

  9. Construction and Commissioning of A 248 m-long Beamline with X-ray Undulator Light Source

    SciTech Connect

    Suzuki, Yoshio; Uesugi, Kentaro; Takimoto, Naoki; Fukui, Tomoki; Aoyama, Kohki; Takeuchi, Akihisa; Takano, Hidekazu; Yagi, Naoto; Mochizuki, Tetsuro; Goto, Shunji; Takeshita, Kunikazu; Takahashi, Sunao; Ohashi, Haruhiko; Furukawa, Yukito; Ohata, Tohru; Matsushita, Tomohiro; Ishizawa, Yasuhide; Yamazaki, Hiroshi; Yabashi, Makina

    2004-05-12

    A medium-length beamline with undulator source, BL20XU at SPring-8, was constructed, and opened to public use. The distance from source point to the end of the beamline is 248 m. By utilizing the long beam transport path, the beamline has advantages for experiment that requires high spatial coherence in hard X-ray regions.

  10. 17 CFR 248.14 - Exceptions to notice and opt out requirements for processing and servicing transactions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...: Privacy of Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.14... service providers and joint marketing, do not apply if you disclose nonpublic personal information as... connection with: (1) Processing or servicing a financial product or service that a consumer requests...

  11. 17 CFR 248.14 - Exceptions to notice and opt out requirements for processing and servicing transactions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...: Privacy of Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.14... service providers and joint marketing, do not apply if you disclose nonpublic personal information as... connection with: (1) Processing or servicing a financial product or service that a consumer requests...

  12. Fast Facts: Recent Statistics from the Library Research Service, Nos. 248-255. March-December 2007

    ERIC Educational Resources Information Center

    Online Submission, 2007

    2007-01-01

    Issues 248 through 255 of "Fast Facts" from the Library Research Service present data gleaned from libraries in Colorado and across the nation. Topics addressed in these "Fast Facts" from 2007 include the library labor market, the benefits to libraries of using a statewide courier service, and the results of a patron survey at…

  13. FERROPORTIN Q248H, DIETARY IRON AND SERUM FERRITIN IN COMMUNITY AFRICAN AMERICANS WITH LOW TO HIGH ALCOHOL CONSUMPTION

    PubMed Central

    Gordeuk, Victor R.; Diaz, Sharmin F.; Onojobi, Gladys O.; Kasvosve, Ishmael; Debebe, Zufan; Edossa, Amanuel; Pantin, Jeremy M.; Xiong, Shigang; Nekhai, Sergei; Nouraie, Mehdi; Tsukamoto, Hidekazu; Taylor, Robert E.

    2012-01-01

    Background Alcohol consumption is associated with increased iron stores. In sub-Saharan Africa, high dietary ionic iron and the ferroportin Q248H allele have also been implicated in iron accumulation. We examined the associations of ferroportin Q248H, alcohol and dietary iron with serum ferritin, aspartate aminotransaminase (AST) and alanine aminotransaminase (ALT) concentrations in African Americans. Methods Inner-city African Americans (103 men, 40 women) were recruited from the community according to reported ingestion of >4 alcoholic drinks per day or <2 per week. Typical daily heme iron, non-heme iron and alcohol were estimated using University of Hawaii’s multiethnic dietary questionnaire. Based on dietary questionnaire estimates we established categories of < versus ≥56 g alcohol per day, equivalent to 4 alcoholic drinks per day assuming 14 g alcohol per drink. Results Among 143 participants, 77% drank <56 g alcohol/day and 23% ≥56 g/d as estimated by the questionnaire. The prevalence of ferroportin Q248H was 23.3% with alcohol >56 g/d versus 7.5% with lower amounts (P=0.012). Among subjects with no history of HIV disease, serum ferritin concentration had positive relationships with male gender (P=0.041), alcohol consumption (P=0.021) and ALT concentration (P=0.0001) but not with dietary iron intake or ferroportin Q248H. Serum AST and ALT concentrations had significant positive associations with male gender and hepatitis C seropositivity but not with alcohol or dietary iron intake or ferroportin Q248H. Conclusions Our findings suggest a higher prevalence of ferroportin Q248H with greater alcohol consumption, and this higher prevalence raises the possibility that the allele might ameliorate the toxicity of alcohol. Our results suggest that alcohol but not dietary iron contributes to higher body iron stores in African Americans. Studies with larger numbers of participants are needed to further clarify the relationship of ferroportin Q248H with the

  14. Large Scale Outflow from a Radio Loud AGN in Merging Galaxies at Redshift 2.48

    NASA Astrophysics Data System (ADS)

    Shih, Hsin-Yi; Stockton, Alan

    We present observations of a remarkable compact group of galaxies at z = 2.48. Four galaxies, all within 40 kpc of each other, surround a powerful high redshift radio source. This group comprises two compact red passive galaxies and a pair of merging galaxies. One of the red galaxies, with an apparent stellar mass of 3.6×1011 M⊙ and an effective radius of 470 pc, is one of the most extreme examples of a massive quiescent compact galaxy found so far. One of the pair of merging galaxies hosts the AGN producing the large powerful radio structure. The merger is massive and enriched, consistent with the mass-metallicity relation expected at this redshift. Close to the merging nuclei, the emission lines exhibit broad and asymmetric profiles that suggest outflows powered either by a very young expanding radio jet or by AGN radiation. At >~ 50 kpc from the system, we found a fainter extended-emission region that may be a part of a radio jet-driven outflow.

  15. In situ bow change of Al-alloy MEMS micromirrors during 248-nm laser irradiation

    NASA Astrophysics Data System (ADS)

    Mai, Alexander; Bunce, Christopher; Hübner, Rene; Pahner, Daniel; Dauderstädt, Ulrike

    2016-07-01

    Micromirror based spatial light modulators (SLMs) developed by the Fraunhofer Institute for Photonic Microsystems are well established in microlithography applications. Serving, e.g., as reflective, programmable photomasks in deep-UV mask writers, they enable highly flexible pattern generation. During operation, the micromirror bow significantly impacts contrast and the resolvable feature size of generated patterns. In some situations, MEMS micromirrors tend to change their bow during laser irradiation. A test regime including a characterization unit for the in situ analysis of MEMS micromirror topology has been developed to measure the bow change under various irradiation conditions. Experiments in which SLMs were irradiated by a 1-kHz, 248-nm pulse laser revealed that mirror bowing can occur in both directions (concave and convex). The bowing direction is dependent upon the applied irradiation parameters such as pulse-energy density, pulse number, and the deposited energy. Sustained irradiation at energy densities exceeding a certain limit can potentially become a limiting factor for the resolvable feature sizes of the patterns generated and, therefore, for the usable SLM lifespan.

  16. Clinical predictors of surgical outcome in cervical spondylotic myelopathy: an analysis of 248 patients.

    PubMed

    Pumberger, M; Froemel, D; Aichmair, A; Hughes, A P; Sama, A A; Cammisa, F P; Girardi, F P

    2013-07-01

    The purpose of this study was to investigate the clinical predictors of surgical outcome in patients with cervical spondylotic myelopathy (CSM). We reviewed a consecutive series of 248 patients (71 women and 177 men) with CSM who had undergone surgery at our institution between January 2000 and October 2010. Their mean age was 59.0 years (16 to 86). Medical records, office notes, and operative reports were reviewed for data collection. Special attention was focused on pre-operative duration and severity as well as post-operative persistence of myelopathic symptoms. Disease severity was graded according to the Nurick classification. Our multivariate logistic regression model indicated that Nurick grade 2 CSM patients have the highest chance of complete symptom resolution (p < 0.001) and improvement to normal gait (p = 0.004) following surgery. Patients who did not improve after surgery had longer duration of myelopathic symptoms than those who did improve post-operatively (17.85 months (1 to 101) vs 11.21 months (1 to 69); p = 0.002). More advanced Nurick grades were not associated with a longer duration of symptoms (p = 0.906). Our data suggest that patients with Nurick grade 2 CSM are most likely to improve from surgery. The duration of myelopathic symptoms does not have an association with disease severity but is an independent prognostic indicator of surgical outcome.

  17. A COMPACT GROUP OF GALAXIES AT Z = 2.48 HOSTING AN AGN-DRIVEN OUTFLOW

    SciTech Connect

    Shih, Hsin-Yi; Stockton, Alan E-mail: stockton@ifa.hawaii.edu

    2015-12-10

    We present observations of a remarkable compact group of galaxies at z = 2.48. Four galaxies, all within 40 kpc of each other, surround a powerful high-redshift radio source. This group comprises two compact red passive galaxies and a pair of merging galaxies. One of the red galaxies, with an apparent stellar mass of 3.6 × 10{sup 11}M{sub ⊙} and an effective radius of 470 pc, is one of the most extreme examples of a massive quiescent compact galaxy found so far. One of the pair of merging galaxies hosts the active galactic nucleus (AGN) producing the large powerful radio structure. The merger is massive and enriched, consistent with the mass–metallicity relation expected at this redshift. Close to the merging nuclei, the emission lines exhibit broad and asymmetric profiles that suggest outflows powered either by a very young expanding radio jet or by AGN radiation. At ≳50 kpc from the system, we found a fainter extended-emission region that may be a part of a radio-jet-driven outflow.

  18. Photodissociation of the Propargyl (C3D3) Radicals at 248 nm and 193 nm

    SciTech Connect

    Neumark., D.M.; Crider, P.E.; Castiglioni, L.; Kautzman, K.K.

    2009-01-21

    The photodissociation of perdeuterated propargyl (D{sub 2}CCCD) and propynyl (D{sub 3}CCC) radicals was investigated using fast beam photofragment translational spectroscopy. Radicals were produced from their respective anions by photodetachment at 540 nm and 450 nm (below and above the electron affinity of propynyl). The radicals were then photodissociated by 248 nm or 193 nm light. The recoiling photofragments were detected in coincidence with a time- and position-sensitive detector. Three channels were observed: D{sub 2} loss, CD + C{sub 2}D{sub 2}, and CD{sub 3} + C{sub 2}. Obervation of the D loss channel was incompatible with this experiment and was not attempted. Our translational energy distributions for D{sub 2} loss peaked at nonzero translational energy, consistent with ground state dissociation over small (< 1 eV) exit barriers with respect to separated products. Translational energy distributions for the two heavy channels peaked near zero kinetic energy, indicating dissociation on the ground state in the absence of exit barriers.

  19. First calorimetric determination of heat of extraction of 248Cm in a bi-phasic system

    SciTech Connect

    Leigh R. Martin; Peter R. Zalupski

    2011-06-01

    This report presents a summary of the work performed to meet FCR&D level 2 milestone M21SW050201, 'Complete the first calorimetric determination of heat of extraction of 248Cm in a bi-phasic system'. This work was carried out under the auspices of the Thermodynamics and Kinetics FCR&D work package. To complement previous work undertaken under this work package we have extended out heat of extraction studies by di-2-ethyl-hexyl-phosphoric acid to curium. This report also details the heat of extraction of samarium in the same system. This work was performed to not only test the methodology but also to check for consistency with the heats of extraction obtained with those in the prior literature. The heat of extraction for samarium that was obtained in this study was -9.6 kJ mol-1, which is in reasonable agreement with the previously obtained value of -10.9 kJ mol-1. The curium heat of extraction was performed under two sets of conditions and the obtained heats of extraction were in reasonable agreement with each other at -16.0 {+-} 1.1 and -16.8 {+-} 1.5 kJ mol-1.

  20. 37 CFR 1.248 - Service of papers; manner of service; proof of service in cases other than interferences and trials.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... service; proof of service in cases other than interferences and trials. 1.248 Section 1.248 Patents...; manner of service; proof of service in cases other than interferences and trials. (a) Service of papers...) or § 42.6(e) of this title for service of papers in contested cases or trials before the Patent Trial...

  1. 37 CFR 1.248 - Service of papers; manner of service; proof of service in cases other than interferences and trials.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... service; proof of service in cases other than interferences and trials. 1.248 Section 1.248 Patents...; manner of service; proof of service in cases other than interferences and trials. (a) Service of papers...) or § 42.6(e) of this title for service of papers in contested cases or trials before the Patent Trial...

  2. Association of ferroportin Q248H polymorphism with elevated levels of serum ferritin in African-Americans in the Hemochromatosis and Iron Overload Screening (HEIRS) Study

    PubMed Central

    Rivers, Charles A.; Barton, James C.; Gordeuk, Victor R.; Acton, Ronald T.; Speechley, Mark R.; Snively, Beverly M.; Leiendecker-Foster, Catherine; Press, Richard D.; Adams, Paul C.; McLaren, Gordon D.; Dawkins, Fitzroy W.; McLaren, Christine E.; Reboussin, David M.

    2007-01-01

    The ferroportin (FPN1) Q248H polymorphism has been associated with increased serum ferritin (SF) levels in sub-Saharan Africans and in African Americans (AA). AA participants of the HEIRS Study who did not have HFE C282Y or H63D who had elevated initial screening SF (≥300 μg/L in men and ≥200 μg/L in women) (defined as cases) were frequency-matched to AA participants with normal SF (defined as controls) to investigate the association of the Q248H with elevated SF. 10.4% of cases and 6.7% of controls were Q248H heterozygotes (P = 0.257). Q248H homozygosity was observed in 0.5% of the cases and none of the controls. The frequency of Q248H was higher among men with elevated SF than among control men (P = 0.047); corresponding differences were not observed among women. This appeared to be unrelated to self-reports of a previous diagnosis of liver disease. Men with elevated SF were three times more likely than women with elevated SF to have Q248H (P = 0.012). There were no significant differences in Q248H frequencies in men and women control participants. We conclude that the frequency of the FPN1 Q248H polymorphism is greater in AA men with elevated SF than in those with normal SF. PMID:17276706

  3. Ion Imaging Studies of CH_2I_2 Photodissociation at 248 NM

    NASA Astrophysics Data System (ADS)

    Lehman, Julia H.; Li, Hongwei; Lester, Marsha I.

    2013-06-01

    CH_2I_2 plays an important role in atmospheric chemistry as a significant natural source of organohalide compounds. The photodissociation dynamics of CH_2I_2 in the ultraviolet range of 277-305 nm via the two lowest B_1 excited states has been well studied using one-color velocity map ion imaging (VMI) and photofragment translational spectroscopy. In this two-color experimental study, CH_2I_2 is photodissociated by 248 nm via the B_2 or A_1 excited states to give rise to CH_2I and I (^2P_3_/_2) or I^* (^2P_1_/_2). The iodine atoms are then state selectively ionized using a (2+1) resonance-enhanced multiphoton ionization process near 310 nm and detected by VMI. Preliminary results show about 85% of the available energy is being funneled into the internal energy of the CH_2I fragment, consistent with prior infrared emission results of Baughcum and Leone. The anisotropy parameter derived from the image indicates this is a fast dissociation process and reflects the character of the electronic transition. The internal energy distribution of the CH_2I fragment is of particular interest because of its subsequent reaction with O_2 in a near thermo-neutral reaction to produce the smallest Criegee intermediate, CH_2OO. We anticipate that the internal energy contained in CH_2I will likely be carried into CH_2OO. S. L. Baughcum and S. R. Leone, J. Chem. Phys. 72, 6531 (1980).

  4. Photodissociation of dibromoethanes at 248 nm: An ignored channel of Br{sub 2} elimination

    SciTech Connect

    Lee, Hsin-Lung; Lee, Ping-Chen; Tsai, Po-Yu; Lin, King-Chuen; Kuo, H. H.; Chen, P. H.; Chang, A. H. H.

    2009-05-14

    Br{sub 2} molecular elimination is probed in the photodissociation of 1,1- and 1,2-C{sub 2}H{sub 4}Br{sub 2} isomeric forms at 248 nm by using cavity ring-down absorption spectroscopy. Their photodissociation processes differ markedly from each other. The quantum yield of the Br{sub 2} fragment in 1,2-dibromoethane is 0.36{+-}0.18, in contrast to a value of 0.05{+-}0.03 in 1,1-dibromoethane. The vibrational population ratios of Br{sub 2}(v=1)/Br{sub 2}(v=0) are 0.8{+-}0.1 and 0.5{+-}0.2 for 1,2- and 1,1-dibromoethanes, respectively. The Br{sub 2} yield densities are found to increase by a factor of 35% and 190% for 1,2- and 1,1-dibromoethanes within the same temperature increment. In the ab initio potential energy calculations, the transition state (TS) along the adiabatic ground state surface may correlate to the Br{sub 2} products. The TS energy for 1,2-dibromoethane is well below the excitation energy at 483 kJ/mol, whereas that for 1,1-dibromoethane is slightly above. Such a small TS energy barrier impedes the photodissociation of the ground state 1,1-dibromoethane such that the production yield of Br{sub 2} may become relatively low, but rise rapidly with the temperature. The TS structure shows a larger bond distance of Br-Br in 1,2-dibromoethane than that in 1,1-dibromoethane. That explains why the former isomer may result in hotter vibrational population of the Br{sub 2} fragments.

  5. Decontamination and decommissioning of rooms 62-248 and 62-250 at Ernest Orlando Lawrence Berkeley National Laboratory

    SciTech Connect

    Garabedian, G.

    1996-05-01

    This document details the decontamination and decommissioning (D&D) process of Rooms 248 and 250 of Building 62 at the Ernest Orlando Lawrence Berkeley National Laboratory (LBNL). The document describes the D&D efforts for the rooms, their contents, and adjacent areas containing ancillary equipment. The rooms and equipment, before being released, were required to meet the unrestricted release criteria and requirements set forth in DOE orders 5400.5 and 5480.11, LBNL`s internal release-criteria procedure (EH&S Procedure 708), and the LBNL Radiological Control Manual. The radioactive material and items not meeting the release criteria were either sent to the Hazardous Waste Handling Facility (HWHF) for disposal or transferred to other locations approved for radioactive material. The D&D was undertaken by the Radiation Protection Group of LBNL`s Environment, Health and Safety (EH&S) Division at the request of the Materials Sciences Division. Current and past use of radioactive material in both Rooms 248 and 250 necessitated the D&D in order to release both rooms for nonradioactive work. (1) Room 248 was designated a {open_quotes}controlled area.{close_quotes} There was contained radioactive material in some of the equipment. The previous occupants of Room 248 had worked with radioactive materials. (2) Room 250 was designated a {open_quotes}Radioactive Materials Management Area{close_quotes} (RMMA) because the current occupants used potentially dispersible radioisotopes. Both laboratories, during the occupancy of U.C. Berkeley Professor Leo Brewer and Ms. Karen Krushwitz, were kept in excellent condition. There was a detailed inventory of all radioactive materials and chemicals. All work and self surveys were documented. The labs were kept extremely orderly, clean, and in compliance. In October 1993 Ms. Krushwitz received an award in recognition of her efforts in Environmental Protection, Health, and Safety at LBNL.

  6. Site Specific Interaction of the Polyphenol EGCG with the SEVI Amyloid Precursor Peptide PAP(248–286)

    PubMed Central

    Popovych, Nataliya; Brender, Jeffrey R.; Soong, Ronald; Vivekanandan, Subramanian; Hartman, Kevin; Basrur, Venkatesha; Macdonald, Peter M.; Ramamoorthy, Ayyalusamy

    2012-01-01

    Recently, a 39 amino acid peptide fragment from prostatic acid phosphatase has been isolated from seminal fluid that can enhance infectivity of the HIV virus by up to four to five orders of magnitude. PAP(248–286) is effective in enhancing HIV infectivity only when it is aggregated into amyloid fibers termed SEVI. The polyphenol EGCG (epigallocatechin-3-gallate) has been shown to disrupt both SEVI formation and HIV promotion by SEVI, but the mechanism by which it accomplishes this task is unknown. Here we show that EGCG interacts specifically with the side-chains of monomeric PAP(248–286) in two regions (K251-R257 and N269-I277) of primarily charged residues, particularly lysine. The specificity of interaction to these two sites is contrary to previous studies on the interaction of EGCG with other amyloidogenic proteins, which showed the nonspecific interaction of EGCG with exposed backbone sites of unfolded amyloidogenic proteins. This interaction is specific to EGCG as the related gallocatechin (GC) molecule, which shows greatly decreased anti-amyloid activity, exhibits minimal interaction with monomeric PAP(248–286). The EGCG binding was shown to occur in two steps, with the initial formation of a weakly bound complex followed by a pH dependent formation of a tightly bound complex. Experiments in which the lysine residues of PAP(248–286) have been chemically modified suggest the tightly bound complex is created by Schiff-base formation with lysine residues. The results of this study could aid in the development of small molecule inhibitors of SEVI and other amyloid proteins. PMID:22360607

  7. X-RAY EMISSION FROM STELLAR JETS BY COLLISION AGAINST HIGH-DENSITY MOLECULAR CLOUDS: AN APPLICATION TO HH 248

    SciTech Connect

    López-Santiago, J.; Ustamujic, S.; Castro, A. I. Gómez de; Bonito, R.; Orlando, S.; Orellana, M.; Miceli, M.; Albacete-Colombo, J. F.

    2015-06-10

    We investigate the plausibility of detecting X-ray emission from a stellar jet that impacts a dense molecular cloud, a scenario that may be typical for classical T Tauri stars with jets in dense star-forming complexes. We first model the impact of a jet against a dense cloud using two-dimensional axisymmetric hydrodynamic simulations, exploring different configurations of the ambient environment. Then, we compare our results with XMM-Newton observations of the Herbig–Haro object HH 248, where extended X-ray emission aligned with the optical knots is detected at the edge of the nearby IC 434 cloud. Our simulations show that a jet can produce plasma with temperatures up to 10{sup 7} K, consistent with production of X-ray emission, after impacting a dense cloud. We find that jets denser than the ambient medium but less dense than the cloud produce detectable X-ray emission only at impact with the cloud. From an exploration of the model parameter space, we constrain the physical conditions (jet density and velocity and cloud density) that reproduce the intrinsic luminosity and emission measure of the X-ray source possibly associated with HH 248 well. Thus, we suggest that the extended X-ray source close to HH 248 corresponds to a jet impacting a dense cloud.

  8. X-ray Emission from Stellar Jets by Collision against High-density Molecular Clouds: an Application to HH 248

    NASA Astrophysics Data System (ADS)

    López-Santiago, J.; Bonito, R.; Orellana, M.; Miceli, M.; Orlando, S.; Ustamujic, S.; Albacete-Colombo, J. F.; de Castro, E.; Gómez de Castro, A. I.

    2015-06-01

    We investigate the plausibility of detecting X-ray emission from a stellar jet that impacts a dense molecular cloud, a scenario that may be typical for classical T Tauri stars with jets in dense star-forming complexes. We first model the impact of a jet against a dense cloud using two-dimensional axisymmetric hydrodynamic simulations, exploring different configurations of the ambient environment. Then, we compare our results with XMM-Newton observations of the Herbig-Haro object HH 248, where extended X-ray emission aligned with the optical knots is detected at the edge of the nearby IC 434 cloud. Our simulations show that a jet can produce plasma with temperatures up to 107 K, consistent with production of X-ray emission, after impacting a dense cloud. We find that jets denser than the ambient medium but less dense than the cloud produce detectable X-ray emission only at impact with the cloud. From an exploration of the model parameter space, we constrain the physical conditions (jet density and velocity and cloud density) that reproduce the intrinsic luminosity and emission measure of the X-ray source possibly associated with HH 248 well. Thus, we suggest that the extended X-ray source close to HH 248 corresponds to a jet impacting a dense cloud.

  9. Nucleotide sequence analysis of the respiratory syncytial virus subgroup A cold-passaged (cp) temperature sensitive (ts) cpts-248/404 live attenuated virus vaccine candidate.

    PubMed

    Firestone, C Y; Whitehead, S S; Collins, P L; Murphy, B R; Crowe, J E

    1996-11-15

    The complete nucleotide sequence of the RSV cpts-248/404 live attenuated vaccine candidate was determined from cloned cDNA and was compared to that of the RSV A2/HEK7 wild-type, cold-passaged cp-RSV, and cpts-248 virus, which constitute the series of progenitor viruses. RSV cpts-248/404 is more attenuated and more temperature sensitive (ts) (shut-off temperature 36 degrees) than its cpts-248 parent virus (shut-off temperature 38 degrees) and is currently being evaluated in phase I clinical trials in humans. Our ultimate goal is to identify the genetic basis for the host range attenuation phenotype exhibited by cp-RSV (i.e., efficient replication in tissue culture but decreased replication in chimpanzees and humans) and for the ts and attenuation phenotypes of its chemically mutagenized derivatives, cpts-248 and cpts-248/404. Compared with its cpts-248 parent, the cpts-248/404 virus possesses an amino acid change in the polymerase (L) protein and a single nucleotide substitution in the M2 gene start sequence. In total, the cpts-248/404 mutant differs from its wild-type RSV A2/HEK7 progenitor in seven amino acids [four in the polymerase (L) protein, two in the fusion (F) glycoprotein, and one in the (N) nucleoprotein] and one nucleotide difference in the M2 gene start sequence. Heterogeneity at nucleotide position 4 (G or C, negative sense, compared to G in the RSV A2/HEK7 progenitor) in the leader region of vRNA developed during passage of the cpts-248/404 in tissue culture. Biologically cloned derivatives of RSV cpts-248/404 virus that differed at position 4 possessed the same level of temperature sensitivity and exhibited the same level of replication in the upper and lower respiratory tract of mice, suggesting that heterogeneity at this position is not clinically relevant. The determination of the nucleotide sequence of the cpts-248/404 virus will allow evaluation of the stability of the eight mutations that are associated with the attenuation phenotype during

  10. A Compact Group of Galaxies at z = 2.48 Hosting an AGN-driven Outflow

    NASA Astrophysics Data System (ADS)

    Shih, Hsin-Yi; Stockton, Alan

    2015-12-01

    We present observations of a remarkable compact group of galaxies at z = 2.48. Four galaxies, all within 40 kpc of each other, surround a powerful high-redshift radio source. This group comprises two compact red passive galaxies and a pair of merging galaxies. One of the red galaxies, with an apparent stellar mass of 3.6 × 1011M⊙ and an effective radius of 470 pc, is one of the most extreme examples of a massive quiescent compact galaxy found so far. One of the pair of merging galaxies hosts the active galactic nucleus (AGN) producing the large powerful radio structure. The merger is massive and enriched, consistent with the mass-metallicity relation expected at this redshift. Close to the merging nuclei, the emission lines exhibit broad and asymmetric profiles that suggest outflows powered either by a very young expanding radio jet or by AGN radiation. At ≳50 kpc from the system, we found a fainter extended-emission region that may be a part of a radio-jet-driven outflow. Some of the data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. The work is also based, in part, on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan, and on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência, Tecnologia e Inovação (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  11. Acetone photolysis at 248 nm revisited: pressure dependence of the CO and CO2 quantum yields.

    PubMed

    Somnitz, H; Ufer, T; Zellner, R

    2009-10-14

    Pressure dependent CO and CO2 quantum yields in the laser pulse photolysis of acetone at 248 nm and T = 298 K have been measured directly using quantitative infrared diode laser absorption. The experiments cover the pressure range from 50 to 900 mbar. It is found that the quantum yields show a significant dependence on total pressure, with Phi(CO) decreasing from around 0.5 at 20 mbar to approximately 0.3 at 900 mbar. The corresponding CO2 yields as observed when O2 exists in the reaction mixture, exhibit exactly the opposite behaviour. For the sum of both a value of 1.05(-0.05)(+0.02) independent of pressure is obtained, showing that the sum of (Phi(CO) + Phi(CO2)) is a measure for the primary quantum yield in the photolysis of acetone. In addition, CO quantum yields and corresponding pressure dependences were measured in experiments using different bath gases including He, Ar, Kr, SF6, and O2 as third body colliders. The theoretical framework in which we discuss these data is based on our previous findings that the pressure dependence of the CO yield is a consequence of a stepwise fragmentation mechanism during which acetone decomposes initially into methyl and a vibrationally 'hot' acetyl radical, with the latter being able to decompose promptly into methyl plus CO. The pressure dependence of the CO yield then originates from the second step and is modelled quantitatively via statistical dynamical calculations using a combination of RRKM theory with a time-dependent master equation (ME) approach. From a comparison of experiment with theory the amount of excess energy in the vibrationally hot acetyl radicals (E* approximately 65 kJ mol(-1)) as well as the characteristic collision parameters for interaction of acetyl with the different bath gases were derived. Values of 90, 280, 310, 545, 550 and 1800 cm(-1) for the average energy transferred per downward collision for the bath gases He, Ar, Kr, O2, N2, and SF6, respectively, are obtained. The calculations also

  12. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ.

    PubMed

    Wang, Huihui; Bao, Wei; Jiang, Feizhou; Che, Qi; Chen, Zheng; Wang, Fangyuan; Tong, Huan; Dai, Chenyun; He, Xiaoying; Liao, Yun; Liu, Binya; Sun, Jing; Wan, Xiaoping

    2015-05-01

    P53 mutation plays a pivotal role in tumorigenesis of endometrial cancer (EC), here we report that the gain-of-function mutant p53-R248Q targets the proteasome activator REGγ to promote EC progression. Increased p53 expression significantly correlated with high pathological grade and lymph node metastasis in EC specimens. Manipulation of p53-R248Q in EC cells caused coincident changes in REGγ expression, and chromatin immunoprecipitation coupled with PCR further indicated that p53-R248Q bound to the REGγ gene promoter at a p53 responsive element. Silencing of REGγ in EC cells attenuated the cell proliferation, migration and invasion abilities, whereas overexpression of p53-R248Q rescued these activities. Overexpression of REGγ also induced an epithelial-mesenchymal transition phenotype. Moreover, a mouse xenograft tumor model showed that REGγ promoted tumor growth, further demonstrating a p53-R248Q-REGγ oncogenic pathway. Finally, examination of EC and normal endometrium specimens confirmed the oncogenic role of REGγ, in that REGγ was more highly overexpressed in p53-positive specimens than in p53-negative specimens. Our data suggest that REGγ is a promising therapeutic target for EC with the p53-R248Q mutation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  13. Gene-based analysis identified the gene ZNF248 is associated with late-onset asthma in African Americans.

    PubMed

    Wang, Leyao; Salinas, Yasmmyn D; DeWan, Andrew T

    2016-07-01

    Late-onset asthma (LOA) has distinct characteristics and its pathogenesis might rely on unique pathways. Although current studies are focused primarily on childhood asthma, more research is needed to show the mechanisms underlying LOA. To conduct genomewide association analysis and gene-based analysis to identify single-nucleotide polymorphisms and genes associated with LOA. The Women's Health Initiative (WHI) observational cohort and the Multi-Ethnic Study of Atherosclerosis (MESA) were used to identify subjects with LOA. The association between LOA and body mass index and smoking was evaluated. In the discovery stage of the genetic analysis, 1,218 African American subjects from WHI with genotype data (271 cases and 947 controls) were used for single-nucleotide polymorphism and gene-based association analyses. Significant or suggestive results were subsequently investigated in an independent African American population from MESA (38 cases and 806 controls). In WHI, the relative odds for LOA in obese vs normal-weight subjects was 2.55 (95% confidence interval 1.74-3.76). Ever smokers also had greater odds for LOA compared with never smokers (odds ratio 1.59, 95% confidence interval 1.21-2.09). The same trends were observed in MESA. In WHI, 6 single-nucleotide polymorphisms were associated with LOA at a genomewide-suggestive significance level (P < 1.0 × 10(-5)). The gene ZNF248 was associated with LOA and reached genomewide significance (P = 4.0 × 10(-7)). In MESA, the association between ZNF248 and LOA was successfully replicated (P = .015). Smoking and obesity are risk factors for LOA. ZNF248 confers increased susceptibility to LOA in African Americans. Copyright © 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  14. Effect of acid labile ether protecting groups on the oxide etch resistance and lithographic performance of 248-nm resists

    NASA Astrophysics Data System (ADS)

    Varanasi, Pushkara R.; Cornett, Kathleen M.; Lawson, Margaret C.

    2000-06-01

    In our attempts to develop etch resistance 248 nm positive resists, we have designed and synthesized thermally stable and acid sensitive methylbenzyl ether (MBE) protected poly(hydroxystyrene) derivatives. Results presented in this paper clearly illustrate that the MBE protecting group provides superior etch resistance to conventional carbonate, ester and acetal/ketal based protecting groups. It is also shown that the MBE protecting group is thermally stable and undergoes acid catalyzed deprotection leading to preferential rearrangement products due to electrophilic ring substitution. Such a rearrangement is shown to provide a unique mechanism to reduce/eliminate resist shrinkage and improve lithographic performance.

  15. Quantum yields for OH production from 193 and 248 nm photolysis of HNO3 and H2O2

    NASA Astrophysics Data System (ADS)

    Schiffman, A.; Nelson, D. D., Jr.; Nesbitt, D. J.

    1993-05-01

    Flash kinetic spectroscopy in a flow tube is used to measure at room temperature the absolute yields for OH production from 193 and 248 nm photolysis of HNO3 and H2O2. The OH radicals are produced by excimer laser photolysis and probed via direct absorption of high resolution tunable IR laser light. The results indicate quantum yields for both precursors at both wavelengths which are less than the maximum possible values of 1 for H2O2. The present measurements are discussed in light of contrasting results suggested from other work.

  16. Comparative analysis of stable ultrahigh power-density 248 nm channels formed in Kr and Xe cluster targets

    NASA Astrophysics Data System (ADS)

    Borisov, Alex B.; McCorkindale, John C.; Poopalasingam, Sankar; Longworth, James W.; Rhodes, Charles K.

    2013-09-01

    Comparative single-pulse studies of self-trapped plasma channel formation in Xe and Kr cluster targets produced with 1-2 TW femtosecond 248 nm pulses reveal energy efficient channel formation (>90%) and highly robust stability for the channeled propagation in both materials. Images of the channel morphology produced by Thomson scattering from the electron density and direct visualization of the Xe(M) and Kr(L) x-ray emission from radiating ions illustrate the (1) channel formation, (2) the narrow region of confined trapped propagation, (3) the abrupt termination of the channel that occurs at the point the power falls below the critical power Pcr, and, in the case of Xe channels, (4) the presence of saturated absorption of Xe(M) radiation that generates an extended peripheral zone of ionization. The measured rates for energy deposition per unit length are ˜ 1.46 J cm-1 and ˜ 0.82 J cm-1 for Xe and Kr targets, respectively, and the single pulse Xe(M) energy yield is estimated to be > 50 mJ, a value indicating an efficiency >20% for ˜ 1 keV x-ray production from the incident 248 nm pulse.

  17. Laboratory studies of 3.3 micron emission from naphthalene induced by 193 and 248 nanometer excitation

    NASA Technical Reports Server (NTRS)

    Williams, Richard M.; Leone, Stephen R.

    1995-01-01

    Laboratory studies of infrared emission from gas-phase naphthalene in the 3.3 micrometer region following ultraviolet laser excitation are used to interpret the unidentified infrared bands observed in many astronomical objects. A time-resolved Fourier transform infrared emission technique acquires the time and spectrally resolved data. Two excitation wavelengths are employed: 193 nm and 248 nm. The infrared emission features are strongly dependent on the initial excitation energy. Wavelength-resolved spectra recorded 6.8 microseconds after the laser pulse show a 45/cm redshift from the gas-phase absorption spectra for 193 nm excitation and 25/cm for 248 nm excitation. We hypothesize that a series of sequence bands originating from the highly vibrationally excited ensemble of molecules is responsible for the observed shift. As collisional and radiative deactivation removes energy from the highly vibrationally excited molecules, the maximum in the emission profile gradually approaches the customary absorption maximum. This indicates that the amount of redshift is strongly dependent on the amount of internal vibrational energy in the molecule at the time of the vibrational transition.

  18. A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection

    PubMed Central

    Chen, Jinquan; Ren, Ruxia; Tan, Suiyi; Zhang, Wanyue; Zhang, Xuanxuan; Yu, Fei; Xun, Tianrong; Jiang, Shibo; Liu, Shuwen; Li, Lin

    2015-01-01

    Background Semen is a major vehicle for HIV transmission. Prostatic acid phosphatase (PAP) fragments, such as PAP248-286, in human semen can form amyloid fibrils to enhance HIV infection. Other endogenous or exogenous factors present during sexual intercourse have also been reported to promote the formation of seminal amyloid fibrils. Methodology and Principal Findings Here, we demonstrated that a synthetic 15-residue peptide derived from the HIV-1 gp120 coreceptor-binding region, designated enhancing peptide 2 (EP2), can rapidly self-assemble into nanofibers. These EP2-derivated nanofibers promptly accelerated the formation of semen amyloid fibrils by PAP248-286, as shown by Thioflavin T (ThT) and Congo red assays. The amyloid fibrils presented similar morphology, assessed via transmission electron microscopy (TEM), in the presence or absence of EP2. Circular dichroism (CD) spectroscopy revealed that EP2 accelerates PAP248-286 amyloid fibril formation by promoting the structural transition of PAP248-286 from a random coil into a cross-β-sheet. Newly formed semen amyloid fibrils effectively enhanced HIV-1 infection in TZM-bl cells and U87 cells by promoting the binding of HIV-1 virions to target cells. Conclusions and Significance Nanofibers composed of EP2 promote the formation of PAP248-286 amyloid fibrils and enhance HIV-1 infection. PMID:26656730

  19. Helical Conformation of the SEVI Precursor Peptide PAP248-286, a Dramatic Enhancer of HIV Infectivity, Promotes Lipid Aggregation and Fusion

    PubMed Central

    Brender, Jeffrey R.; Hartman, Kevin; Gottler, Lindsey M.; Cavitt, Marchello E.; Youngstrom, Daniel W.; Ramamoorthy, Ayyalusamy

    2009-01-01

    In previous in vivo studies, amyloid fibers formed from a peptide ubiquitous in human seminal fluid (semen-derived enhancer of viral infection (SEVI)) were found to dramatically enhance the infectivity of the HIV virus (3–5 orders of magnitude by some measures). To complement those studies, we performed in vitro assays of PAP248-286, the most active precursor to SEVI, and other polycationic polymers to investigate the physical mechanisms by which the PAP248-286 promotes the interaction with lipid bilayers. At acidic (but not at neutral) pH, freshly dissolved PAP248-286 catalyzes the formation of large lipid flocculates in a variety of membrane compositions, which may be linked to the promotion of convective transport in the vaginal environment rather than transport by a random Brownian motion. Furthermore, PAP248-286 is itself fusiogenic and weakens the integrity of the membrane in such a way that may promote fusion by the HIV gp41 protein. An α-helical conformation of PAP248-286, lying parallel to the membrane surface, is implicated in promoting bridging interactions between membranes by the screening of the electrostatic repulsion that occurs when two membranes are brought into close contact. This suggests that nonspecific binding of monomeric or small oligomeric forms of SEVI in a helical conformation to lipid membranes may be an additional mechanism by which SEVI enhances the infectivity of the HIV virus. PMID:19883590

  20. XMM-Newton and INTEGRAL view of the hard state of EXO 1745-248 during its 2015 outburst

    NASA Astrophysics Data System (ADS)

    Matranga, M.; Papitto, A.; Di Salvo, T.; Bozzo, E.; Torres, D. F.; Iaria, R.; Burderi, L.; Rea, N.; de Martino, D.; Sanchez-Fernandez, C.; Gambino, A. F.; Ferrigno, C.; Stella, L.

    2017-07-01

    Context. Transient low-mass X-ray binaries (LMXBs) often show outbursts that typically last a few weeks and are characterized by a high X-ray luminosity (Lx ≈ 1036-1038 erg s-1), while most of the time they are found in X-ray quiescence (LX ≈ 1031-1033 erg s-1). The source EXO 1745-248 is one of them. Aims: The broad-band coverage and sensitivity of the instrument on board XMM-Newton and INTEGRAL offers the opportunity of characterizing the hard X-ray spectrum during the outburst of EXO 1745-248. Methods: We report on quasi-simultaneous XMM-Newton and INTEGRAL observations of the X-ray transient EXO 1745-248 located in the globular cluster Terzan 5, performed ten days after the beginning of the outburst (on 2015 March 16) of the source between March and June 2015. The source was caught in a hard state, emitting a 0.8-100 keV luminosity of ≃ 1037 erg s-1. Results: The spectral continuum was dominated by thermal Comptonization of seed photons with temperature kTin ≃ 1.3 keV, by a cloud with a moderate optical depth τ ≃ 2, and with an electron temperature of kTe ≃ 40 keV. A weaker soft thermal component at temperature kTth ≃ 0.6-0.7 keV and compatible with a fraction of the neutron star radius was also detected. A rich emission line spectrum was observed by the EPIC-pn on board XMM-Newton; features at energies compatible with K-α transitions of ionized sulfur, argon, calcium, and iron were detected, with a broadness compatible with either thermal Compton broadening or Doppler broadening in the inner parts of an accretion disk truncated at 20 ± 6 gravitational radii from the neutron star. Strikingly, at least one narrow emission line ascribed to neutral or mildly ionized iron is needed to model the prominent emission complex detected between 5.5 and 7.5 keV. The different ionization state and broadness suggest an origin in a region located farther from the neutron star than where the other emission lines are produced. Seven consecutive type I bursts

  1. Fission properties of the 1. 5-s spontaneous fission activity produced in bombardmentof /sup 248/Cm with /sup 18/O

    SciTech Connect

    Hoffman, D.C.; Lee, D.; Ghiorso, A.; Nurmia, M.J.; Aleklett, K.; Leino, M.

    1981-08-01

    We have measured the mass and kinetic-energy distributions of fragments from the spontaneous fission of a 1.5-s activity produced in bombardments of /sup 248/Cm with 95-MeV /sup 18/O ions. Its spontaneous fission decay exhibits a very symmetric, narrow (full width at half maximum = 12 mass units) mass distribution, a very high total kinetic energy of 234 +- 2 MeV, and increasing total kinetic energy with increasingly symmetric mass division. Based on its half-life and the similarity of its fission properties to the unique fission properties so far only observed for /sup 258/Fm and /sup 259/Fm, the most likely assignment of this activity is to the known /sup 259/Fm. However, assignment to some as yet undiscovered neutron-rich heavy element isotope such as /sup 260/Md cannot be unequivocally excluded.

  2. Production of new superheavy Z=108-114 nuclei with U238, Pu244, and Cm248,250 targets

    NASA Astrophysics Data System (ADS)

    Feng, Zhao-Qing; Jin, Gen-Ming; Li, Jun-Qing

    2009-11-01

    Within the framework of the dinuclear system (DNS) model, production cross sections of new superheavy nuclei with charged numbers Z=108-114 are analyzed systematically. Possible combinations based on the actinide nuclides U238, Pu244, and Cm248,250 with the optimal excitation energies and evaporation channels are pointed out to synthesize new isotopes that lie between the nuclides produced in the cold fusion reactions and the Ca48-induced fusion reactions experimentally, which are feasible to be constructed experimentally. It is found that the production cross sections of superheavy nuclei decrease drastically with the charged numbers of compound nuclei. Larger mass asymmetries of the entrance channels enhance the cross sections in 2n-5n channels.

  3. Operational tests of the BNL 24.8 kW, 3.8 K helium refrigerator

    NASA Astrophysics Data System (ADS)

    Brown, D. P.; Farah, Y.; Gibbs, R. J.; Schlafke, A. P.; Sondericker, J. H.; Wu, K. C.; Freeman, M.; Ganni, V.; Kowalski, R.; McWilliams, R.

    1985-06-01

    The BNL 24.8 kW refrigeration system is completely installed and major portions of the acceptance tests have been completed. So far, the equipment tested has performed at or above design levels. The room temperature helium compressor station has been completely tested and accepted. The two-stage oil injected screw compressor system exhibited an isothermal efficiency of 57% while delivering a helium flow in excess of 4400 g/s. Data on the performance of the make-up gas cryogenic purifier is given. The refrigerator turbomachinery, 13 expanders and three cold compressors, has been tested at room temperature for mechanical integrity and control stability. The first cooldown to operating temperature will be attempted in late August, 1985.

  4. Two-quasineutron states in {sup 248}{sub 98}Cf and {sup 250}{sub 98}Cf and the neutron-neutron residual interactions.

    SciTech Connect

    Katori, K.; Ahmad, I.; Friedman, A. M.; Physics; Osaka Univ.

    2008-07-01

    Two-quasineutron states in {sup 248}Cf and {sup 250}Cf were investigated by single-neutron transfer reactions, {sup 249}Cf(d,t){sup 248}Cf and {sup 249}Cf(d,p){sup 250}Cf. The majority of levels observed were assigned to 12 bands in {sup 248}Cf and six bands in {sup 250}Cf, constructed from the single-particle states in neighboring Cf nuclei. The effective two-body interactions between two odd neutrons coupled outside a deformed core were deduced from the differences in the energies of the bandheads formed by the parallel and antiparallel coupling of the intrinsic spins of the two single-particle states.

  5. The content of 250Cf and 248Cm in 252Cf neutron sources and the effect on the neutron emission rate.

    PubMed

    Roberts, N J; Jones, L N

    2007-01-01

    One of the most common radionuclide neutron sources used for the calibration of detectors is (252)Cf. However, these sources also contain (250)Cf, which is present in the material from which the sources are made, and (248)Cm, which is formed as the daughter of (252)Cf via alpha-decay. Both decay by spontaneous fission with longer half-lives than (252)Cf. Consequently, as the source becomes older, the emission rate does not follow the decay curve of (252)Cf. Fits have been made to emission rate measurements of (252)Cf sources at NPL spanning over 30 y to deduce their (250)Cf and (248)Cm content. The emission rate of a source can be significantly underestimated if the presence of (250)Cf and (248)Cm is not taken into account, and this has been investigated for a typical (252)Cf source. The importance of this problem to other calibration laboratories and users of (252)Cf sources is emphasised.

  6. Two-quasineutron states in {sub 98}{sup 248}Cf and {sub 98}{sup 250}Cf and the neutron-neutron residual interactions

    SciTech Connect

    Katori, K.; Ahmad, I.; Friedman, A. M.

    2008-07-15

    Two-quasineutron states in {sup 248}Cf and {sup 250}Cf were investigated by single-neutron transfer reactions, {sup 249}Cf(d,t){sup 248}Cf and {sup 249}Cf(d,p){sup 250}Cf. The majority of levels observed were assigned to 12 bands in {sup 248}Cf and six bands in {sup 250}Cf, constructed from the single-particle states in neighboring Cf nuclei. The effective two-body interactions between two odd neutrons coupled outside a deformed core were deduced from the differences in the energies of the bandheads formed by the parallel and antiparallel coupling of the intrinsic spins of the two single-particle states.

  7. In-beam gamma-ray spectroscopy of {sup 248,250,252}Cf by neutron-transfer reactions using a Cf target

    SciTech Connect

    Takahashi, R.; Ishii, T.; Asai, M.; Nagae, D.; Makii, H.; Tsukada, K.; Toyoshima, A.; Ishii, Y.; Matsuda, M.; Makishima, A.; Shizuma, T.; Kohno, T.; Ogawa, M.

    2010-05-15

    The ground-state bands of {sup 248,250,252}Cf have been established up to the 10{sup +}, 12{sup +}, and 10{sup +} states, respectively, by in-beam gamma-ray spectroscopy using neutron-transfer reactions with a 153-MeV {sup 18}O beam and a highly radioactive Cf target. The deexcitation gamma rays in {sup 248,250,252}Cf were identified by taking coincidences with outgoing particles of {sup 16-19}O measured with Si DELTAE-E detectors, and by selecting their kinetic energies. Moments of inertia of {sup 248,250,252}Cf were discussed in terms of the N=152 deformed shell gap.

  8. TP53 gene polymorphisms at codons 11, 72, and 248 and association with endometriosis in a Brazilian population.

    PubMed

    Camargo-Kosugi, C M; D'Amora, P; Kleine, J P F O; Carvalho, C V; Sato, H; Schor, E; Silva, I D C G

    2014-08-26

    We evaluated the association between TP53 gene polymorphisms and endometriosis in Brazilian women. Genomic DNA was extracted from swabs of buccal cells collected from hospital patients. TP53 gene polymorphisms were investigated at three codons: TP53 11 Glu/Gln or Lys (GAG->CAG or AAG), TP53 72 Arg/Pro (CCG->CCC), and TP53 248 Arg/Thr (CGG->TCG) using the polymerase chain reaction-restriction fragment length polymorphism method. TP53 11 presented the following genotypic distribution: the control group was 98.28% homozygous wild-type (Glu) and 1.72% homozygous variant (Gln/Lys), and the heterozygous genotype was not identified. The genotypic distribution in the endometriosis group was 96% homozygous wild-type (Glu) and 4% heterozygous (Glu-Gln/Lys); the homozygous variant genotype was not identified (P = 0.02). TP53 72 showed the following genotypic distribution: the control group was 29.75% homozygous wild-type (Arg), 47.11% heterozygous (Arg-Pro), and 23.14% homozygous variant (Pro). The genotypic distribution in the endometriosis group was 16.15% homozygous wild-type (Arg), 51.54% heterozygous (Arg-Pro), and 32.31% homozygous variant (Pro) (odds ratio = 2.26; 95% confidence interval = 1.19-4.03; P = 0.02). Only one patient had the homozygous TP53 248 genotype (Arg-Trp/Gln); all other patients were homozygous wild-type in both the control and endometriosis groups (P = 0.51; NS). We found that TP53 72 polymorphism may be associated with susceptibility to endometriosis; the presence of at least 1 polymorphic allele increased the chance of disease development by 2.26-fold. Hence, this genetic variant is a potential candidate marker for endometriosis.

  9. Analysis of polymorphisms in codons 11, 72 and 248 of TP53 in Brazilian women with breast cancer.

    PubMed

    Almeida, B C; Kleine, J P F O; Camargo-Kosugi, C M; Lisboa, M R; França, C N; França, J P; Silva, I D C G

    2016-02-22

    The association between TP53 gene polymorphisms and breast cancer (BC) in Brazilian women is a controversial topic. In this cross-sectional study, we evaluated the association between clinical pathological variables and three polymorphisms (TP53*11, TP53*72, and TP53*248) in BC patients and controls. Genomic DNA was extracted from the blood cells of 393 participants; the cancer-free control subjects were 26-72 years old (41 ± 11.03) and the BC patients were 28-80 years old (51 ± 10.70). We used standard polymerase chain reaction-restriction fragment length polymorphism and confirmed the results by genetic sequencing. In TP53*11, there was 100% homozygous Glu distribution in both groups. TP53*72 showed genotypic distribution: in the control group, there was 16.10% homozygous Pro, and 42.44% heterozygous and 41.46% homozygous Arg; in the BC group, there was 15.43% homozygous Pro, and 42.55% heterozygous and 42.02% homozygous Arg. The relative frequency of each allele was 0.37% for Pro and 0.63% for Arg in the control group, and 0.37% for Pro and 0.63% for Arg in the BC group. The nuclear grade (P = 0.0084) and adapted histological grade (P = 0.0265) were associated with TP53*72. The distribution of the codon 72 genotypes did not deviate from Hardy-Weinberg equilibrium in either group. In TP53*248, there was 100% homozygous Arg distribution in both groups. In codon 72, the Arg allele is the most prevalent in Brazilian women. TP53*72 may be associated with susceptibility to BC, although more studies are required to evaluate the profile of Brazilian women with BC.

  10. Nonlinear absorption and optical strength of BaF{sub 2} and Al{sub 2}O{sub 3} at the wavelength of 248 nm

    SciTech Connect

    Morozov, Nikolai V; Sergeev, P B; Reiterov, V M

    1999-11-30

    An experimental investigation was made of the dependence of the transmission of BaF{sub 2} and Al{sub 2}O{sub 3} samples on the intensity of KrF-laser radiation ({lambda} = 248 nm) pulses of 85 ns duration. The two-photon absorption coefficients were found at {lambda} = 248 nm and their values for these two crystals were 0.5 {+-} 0.2 and 2 {+-} 1 cm Gw{sup -1}. The surface and bulk laser breakdown thresholds were determined for these samples. (nonlinear optical phenomena)

  11. High throughput virtual screening and in silico ADMET analysis for rapid and efficient identification of potential PAP248-286 aggregation inhibitors as anti-HIV agents

    NASA Astrophysics Data System (ADS)

    Malik, Ruchi; Bunkar, Devendra; Choudhary, Bhanwar Singh; Srivastava, Shubham; Mehta, Pakhuri; Sharma, Manish

    2016-10-01

    Human semen is principal vehicle for transmission of HIV-1 and other enveloped viruses. Several endogenous peptides present in semen, including a 39-amino acid fragments of prostatic acid phosphatase (PAP248-286) assemble into amyloid fibrils named as semen-derived enhancer of viral infection (SEVI) that promote virion attachment to target cells which dramatically enhance HIV virus infection by up to 105-fold. Epigallocatechin-3-gallate (EGCG), a polyphenolic compound, is the major catechin found in green tea which disaggregates existing SEVI fibers, and inhibits the formation of SEVI fibers. The aim of this study was to screen a number of relevant polyphenols to develop a rational approach for designing PAP248-286 aggregation inhibitors as potential anti-HIV agents. The molecular docking based virtual screening results showed that polyphenolic compounds 2-6 possessed good docking score and interacted well with the active site residues of PAP248-286. Amino acid residues of binding site namely; Lys255, Ser256, Leu258 and Asn265 are involved in binding of these compounds. In silico ADMET prediction studies on these hits were also found to be promising. Polyphenolic compounds 2-6 identified as hits may act as novel leads for inhibiting aggregation of PAP248-286 into SEVI.

  12. Seminal Plasma Accelerates Semen-derived Enhancer of Viral Infection (SEVI) Fibril Formation by the Prostatic Acid Phosphatase (PAP248–286) Peptide*

    PubMed Central

    Olsen, Joanna S.; DiMaio, John T. M.; Doran, Todd M.; Brown, Caitlin; Nilsson, Bradley L.; Dewhurst, Stephen

    2012-01-01

    Amyloid fibrils contained in semen, known as SEVI, or semen-derived enhancer of viral infection, have been shown to increase the infectivity of HIV dramatically. However, previous work with these fibrils has suggested that extensive time and nonphysiologic levels of agitation are necessary to induce amyloid formation from the precursor peptide (a proteolytic cleavage product of prostatic acid phosphatase, PAP248–286). Here, we show that fibril formation by PAP248–286 is accelerated dramatically in the presence of seminal plasma (SP) and that agitation is not required for fibrillization in this setting. Analysis of the effects of specific SP components on fibril formation by PAP248–286 revealed that this effect is primarily due to the anionic buffer components of SP (notably inorganic phosphate and sodium bicarbonate). Divalent cations present in SP had little effect on the kinetics of fibril formation, but physiologic levels of Zn2+ strongly protected SEVI fibrils from degradation by seminal proteases. Taken together, these data suggest that in the in vivo environment, PAP248–286 is likely to form fibrils efficiently, thus providing an explanation for the presence of SEVI in human semen. PMID:22354963

  13. Seminal plasma accelerates semen-derived enhancer of viral infection (SEVI) fibril formation by the prostatic acid phosphatase (PAP248-286) peptide.

    PubMed

    Olsen, Joanna S; DiMaio, John T M; Doran, Todd M; Brown, Caitlin; Nilsson, Bradley L; Dewhurst, Stephen

    2012-04-06

    Amyloid fibrils contained in semen, known as SEVI, or semen-derived enhancer of viral infection, have been shown to increase the infectivity of HIV dramatically. However, previous work with these fibrils has suggested that extensive time and nonphysiologic levels of agitation are necessary to induce amyloid formation from the precursor peptide (a proteolytic cleavage product of prostatic acid phosphatase, PAP(248-286)). Here, we show that fibril formation by PAP(248-286) is accelerated dramatically in the presence of seminal plasma (SP) and that agitation is not required for fibrillization in this setting. Analysis of the effects of specific SP components on fibril formation by PAP(248-286) revealed that this effect is primarily due to the anionic buffer components of SP (notably inorganic phosphate and sodium bicarbonate). Divalent cations present in SP had little effect on the kinetics of fibril formation, but physiologic levels of Zn(2+) strongly protected SEVI fibrils from degradation by seminal proteases. Taken together, these data suggest that in the in vivo environment, PAP(248-286) is likely to form fibrils efficiently, thus providing an explanation for the presence of SEVI in human semen.

  14. Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.

    PubMed

    Khan, K A; Naylor, A J; Khan, A; Noy, P J; Mambretti, M; Lodhia, P; Athwal, J; Korzystka, A; Buckley, C D; Willcox, B E; Mohammed, F; Bicknell, R

    2017-07-03

    The C-type lectin domain containing group 14 family members CLEC14A and CD93 are proteins expressed by endothelium and are implicated in tumour angiogenesis. CD248 (alternatively known as endosialin or tumour endothelial marker-1) is also a member of this family and is expressed by tumour-associated fibroblasts and pericytes. Multimerin-2 (MMRN2) is a unique endothelial specific extracellular matrix protein that has been implicated in angiogenesis and tumour progression. We show that the group 14 C-type lectins CLEC14A, CD93 and CD248 directly bind to MMRN2 and only thrombomodulin of the family does not. Binding to MMRN2 is dependent on a predicted long-loop region in the C-type lectin domain and is abrogated by mutation within the domain. CLEC14A and CD93 bind to the same non-glycosylated coiled-coil region of MMRN2, but the binding of CD248 occurs on a distinct non-competing region. CLEC14A and CD248 can bind MMRN2 simultaneously and this occurs at the interface between endothelium and pericytes in human pancreatic cancer. A recombinant peptide of MMRN2 spanning the CLEC14A and CD93 binding region blocks CLEC14A extracellular domain binding to the endothelial cell surface as well as increasing adherence of human umbilical vein endothelial cells to the active peptide. This MMRN2 peptide is anti-angiogenic in vitro and reduces tumour growth in mouse models. These findings identify novel protein interactions involving CLEC14A, CD93 and CD248 with MMRN2 as targetable components of vessel formation.Oncogene advance online publication, 3 July 2017; doi:10.1038/onc.2017.214.

  15. Bacterial curli protein promotes the conversion of PAP248-286 into the amyloid SEVI: cross-seeding of dissimilar amyloid sequences

    PubMed Central

    Hartman, Kevin; Brender, Jeffrey R.; Monde, Kazuaki; Ono, Akira; Evans, Margery L.; Popovych, Nataliya; Chapman, Matthew R.

    2013-01-01

    Fragments of prostatic acid phosphatase (PAP248-286) in human semen dramatically increase HIV infection efficiency by increasing virus adhesion to target cells. PAP248-286 only enhances HIV infection in the form of amyloid aggregates termed SEVI (Semen Enhancer of Viral Infection), however monomeric PAP248-286 aggregates very slowly in isolation. It has therefore been suggested that SEVI fiber formation in vivo may be promoted by exogenous factors. We show here that a bacterially-produced extracellular amyloid (curli or Csg) acts as a catalytic agent for SEVI formation from PAP248-286 at low concentrations in vitro, producing fibers that retain the ability to enhance HIV (Human Immunodeficiency Virus) infection. Kinetic analysis of the cross-seeding effect shows an unusual pattern. Cross-seeding PAP248-286 with curli only moderately affects the nucleation rate while significantly enhancing the growth of fibers from existing nuclei. This pattern is in contrast to most previous observations of cross-seeding, which show cross-seeding partially bypasses the nucleation step but has little effect on fiber elongation. Seeding other amyloidogenic proteins (IAPP (islet amyloid polypeptide) and Aβ1−40) with curli showed varied results. Curli cross-seeding decreased the lag-time of IAPP amyloid formation but strongly inhibited IAPP elongation. Curli cross-seeding exerted a complicated concentration dependent effect on Aβ1−40 fibrillogenesis kinetics. Combined, these results suggest that the interaction of amyloidogenic proteins with preformed fibers of a different type can take a variety of forms and is not limited to epitaxial nucleation between proteins of similar sequence. The ability of curli fibers to interact with proteins of dissimilar sequences suggests cross-seeding may be a more general phenomenon than previously supposed. PMID:23638387

  16. Dependence of ultraviolet nanosecond laser polymer ablation on polymer molecular weight: Poly(methyl methacrylate) at 248 nm

    NASA Astrophysics Data System (ADS)

    Bounos, Giannis; Selimis, Alexandros; Georgiou, Savas; Rebollar, Esther; Castillejo, Marta; Bityurin, Nikita

    2006-12-01

    We rely on a methodology demonstrated previously for assessing the temperature evolution and polymer viscosity changes in the 248nm irradiation of poly(methyl methacrylate)s (PMMAs) with molecular weights (Mw) ranging from 2.5to996kDa. Briefly, this methodology [G. Bounos et al., J. Appl. Phys. 98, 084317 (2005)] relies on monitoring the formation of aryl products in the irradiation of polymer doped with iodonaphthalene or iodophenanthrene. The results demonstrate that higher temperatures are attained with increasing Mw. The surface temperatures at the corresponding ablation thresholds are estimated to be ˜850-900K for Mw⩾120kDa vs ˜600K for 2.5kDa PMMA. In addition, for all Mw's, melting is demonstrated (viscosity values of ≈101Pas), but it lasts longer for high Mw PMMAs. We ascribe these differences to the fact that low Mw PMMAs dissociate efficiently to desorbing monomers/oligomers, thereby resulting in more efficient energy removal. Even so, the ablation threshold of the high Mw PMMAs is attained at higher fluences. This can be ascribed to the higher fraction of bonds that is required to be broken, and also plausibly to the higher gaseous product pressures that must be attained, for material ejection to be effected. The results are overall well accounted by the bulk photothermal model.

  17. Set-up of an XAFS beamline for measurements between 2.4-8 keV at DORIS III

    NASA Astrophysics Data System (ADS)

    Welter, Edmund

    2010-06-01

    In this paper results from the commissioning phase and from first user experiments of a new EXAFS beamline at the DORIS III storage ring are presented. The bending magnet EXAFS beamline A1 underwent a complete rebuild and now covers the energy range 2.4-8 keV. A Ni-coated toroidal mirror, placed in a 2:1 focusing position and a plane mirror with one Ni coated stripe and one uncoated (SiO2) stripe are used for effective higher harmonics suppression and focusing. The UHV-compatible fixed-exit Double Crystal Monochromator (DCM) is equipped with two Si(111) crystal pairs. The second crystal of one of the two crystal pairs is tilted by 90° around the surface normal to shift the position of glitches. It allows Bragg angles between 5° and 55.5° and continuous scans in quick-EXAFS mode. Test measurements during the commissioning phase proved the excellent performance of the monochromator and a high quality of the XAFS spectra over the entire working range.

  18. 248-nm DUV MoSiON embedded phase-shifting mask for 0.25 micrometer lithography

    NASA Astrophysics Data System (ADS)

    Dao, Giang T.; Liu, Gang; Hainsey, Robert F.; Farnsworth, Jeff N.; Tokoro, Yasuo; Kawada, Susumu; Yamamoto, Tsuneo; Yoshioka, Nobuyuki; Chiba, Akira; Morimoto, Hiroaki

    1995-07-01

    Over the past five years worldwide efforts have been made to develop new techniques for optical lithography enhancement. These techniques include optical proximity correction, off-axis illumination, pupil filtering and phase-shifting mask (PSM). Among many phase-shifting mask approaches, embedded PSM (EPSM) method has drawn significant interest due to its relatively simple reticle fabrication process and excellent lithographic performance, in particular, for dark field mask layers such as contact and via holes. Perhaps, the most difficult task in materializing the EPSM technology is the creation of a thin film structure that controls both phase and transmission. In addition, this film structure must withstand severe environment of mask making process and yet can be inspected and repaired successfully using currently available tool sets. The newly developed MoSiON material meets these requirements and has demonstrated a feasibility for DUV EPSM pilot production. In this paper, characteristics of the DUV lifetime test results. Details of reticle fabrication process including e-beam writing, dry etching, inspection and repair will be presented along with chemical durability data and process capability. Finally, wafer level lithographic performance for contact holes printed on a step-and-scan and a projection aligner will be shown to demonstrate lithographic performance of 248 nm DUV EPSM for 0.25 micrometer lithography.

  19. Dependence of ultraviolet nanosecond laser polymer ablation on polymer molecular weight: Poly(methyl methacrylate) at 248 nm

    SciTech Connect

    Bounos, Giannis; Selimis, Alexandros; Georgiou, Savas; Rebollar, Esther; Castillejo, Marta; Bityurin, Nikita

    2006-12-01

    We rely on a methodology demonstrated previously for assessing the temperature evolution and polymer viscosity changes in the 248 nm irradiation of poly(methyl methacrylate)s (PMMAs) with molecular weights (M{sub w}) ranging from 2.5 to 996 kDa. Briefly, this methodology [G. Bounos et al., J. Appl. Phys. 98, 084317 (2005)] relies on monitoring the formation of aryl products in the irradiation of polymer doped with iodonaphthalene or iodophenanthrene. The results demonstrate that higher temperatures are attained with increasing M{sub w}. The surface temperatures at the corresponding ablation thresholds are estimated to be {approx}850-900 K for M{sub w}{>=}120 kDa vs {approx}600 K for 2.5 kDa PMMA. In addition, for all M{sub w}'s, melting is demonstrated (viscosity values of {approx_equal}10{sup 1} Pa s), but it lasts longer for high M{sub w} PMMAs. We ascribe these differences to the fact that low M{sub w} PMMAs dissociate efficiently to desorbing monomers/oligomers, thereby resulting in more efficient energy removal. Even so, the ablation threshold of the high M{sub w} PMMAs is attained at higher fluences. This can be ascribed to the higher fraction of bonds that is required to be broken, and also plausibly to the higher gaseous product pressures that must be attained, for material ejection to be effected. The results are overall well accounted by the bulk photothermal model.

  20. Analysis of causative microorganism in 248 primary hip arthroplasties revised for infection: a study using the NJR dataset.

    PubMed

    Holleyman, Richard J; Baker, Paul N; Charlett, Andre; Gould, Kate; Deehan, David J

    2016-01-01

    This study aimed to describe the epidemiology of the causative organism in a series of primary hip arthroplasties revised for a diagnosis of periprosthetic joint infection (PJI) in England and Wales. Patient data from the National Joint Registry (NJR) was linked to microbiology data held by Public Health England (PHE) which identified a series of 248 primary hip arthroplasties revised for PJI between 2003 and 2014. Definitive cultures, isolated at time of revision surgery, were available for all cases. Total hip arthroplasty (n = 239, 96%) and hip resurfacing (n = 5, 2%) were the most commonly performed primary procedures. A two-stage revision was the most common operative management (n = 174, 70%). 202 (81%) cases were infected with a single genus microorganism and the most commonly implicated genus was Staphylococcus species (70% of all single genus infections). Staphylococcus species were also the most commonly identified microorganism in mixed genus infections (74% of patient's cultures). There was a significant difference in microorganism distribution when comparing uncemented vs cement implant fixation, with a higher incidence of Gram-negative infection observed in the uncemented group (p = 0.048, Chi-square). Both prophylactic and therapeutic antibiotic regimes should be focused on targeting Staphylococci.